LOCUS       DAEPUT010000001       148962 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.001, whole genome shotgun sequence.
ACCESSION   DAEPUT010000001 DAEPUT010000000
VERSION     DAEPUT010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 148962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 148962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..148962
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.001"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(165..359)
                     /locus_tag="KRL22_000001"
     CDS             complement(165..359)
                     /locus_tag="KRL22_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270531.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
     gene            complement(668..2197)
                     /gene="lysS"
                     /locus_tag="KRL22_000002"
     CDS             complement(668..2197)
                     /gene="lysS"
                     /locus_tag="KRL22_000002"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBH1270532.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2212..2691)
                     /gene="greA"
                     /locus_tag="KRL22_000003"
     CDS             complement(2212..2691)
                     /gene="greA"
                     /locus_tag="KRL22_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBH1270533.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2800..3768)
                     /gene="dusB"
                     /locus_tag="KRL22_000004"
     CDS             complement(2800..3768)
                     /gene="dusB"
                     /locus_tag="KRL22_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBH1270534.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3905..4675)
                     /locus_tag="KRL22_000005"
     CDS             complement(3905..4675)
                     /locus_tag="KRL22_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HBH1270535.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4694..5284)
                     /locus_tag="KRL22_000006"
     CDS             complement(4694..5284)
                     /locus_tag="KRL22_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1270536.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5468..6436)
                     /locus_tag="KRL22_000007"
     CDS             complement(5468..6436)
                     /locus_tag="KRL22_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HBH1270537.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLVVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6429..7406)
                     /locus_tag="KRL22_000008"
     CDS             complement(6429..7406)
                     /locus_tag="KRL22_000008"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBH1270538.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7721..9691)
                     /gene="ftsH"
                     /locus_tag="KRL22_000009"
     CDS             complement(7721..9691)
                     /gene="ftsH"
                     /locus_tag="KRL22_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH1270539.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9725..11113)
                     /gene="tilS"
                     /locus_tag="KRL22_000010"
     CDS             complement(9725..11113)
                     /gene="tilS"
                     /locus_tag="KRL22_000010"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBH1270540.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11296..11724)
                     /locus_tag="KRL22_000011"
     CDS             complement(11296..11724)
                     /locus_tag="KRL22_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBH1270541.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11741..12547)
                     /locus_tag="KRL22_000012"
     CDS             complement(11741..12547)
                     /locus_tag="KRL22_000012"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBH1270542.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12749..13234)
                     /locus_tag="KRL22_000013"
     CDS             complement(12749..13234)
                     /locus_tag="KRL22_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBH1270543.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13285..13944)
                     /gene="spoIIR"
                     /locus_tag="KRL22_000014"
     CDS             complement(13285..13944)
                     /gene="spoIIR"
                     /locus_tag="KRL22_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBH1270544.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14089..14769)
                     /locus_tag="KRL22_000015"
     CDS             complement(14089..14769)
                     /locus_tag="KRL22_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1270545.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14753..15643)
                     /locus_tag="KRL22_000016"
     CDS             complement(14753..15643)
                     /locus_tag="KRL22_000016"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBH1270546.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15761..17311)
                     /locus_tag="KRL22_000017"
     CDS             complement(15761..17311)
                     /locus_tag="KRL22_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HBH1270547.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17405..17671)
                     /locus_tag="KRL22_000018"
     CDS             complement(17405..17671)
                     /locus_tag="KRL22_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBH1270548.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17819..18679)
                     /gene="yabG"
                     /locus_tag="KRL22_000019"
     CDS             complement(17819..18679)
                     /gene="yabG"
                     /locus_tag="KRL22_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HBH1270549.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18763..19701)
                     /locus_tag="KRL22_000020"
     CDS             complement(18763..19701)
                     /locus_tag="KRL22_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HBH1270550.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19811..19972)
                     /locus_tag="KRL22_000021"
     CDS             complement(19811..19972)
                     /locus_tag="KRL22_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270551.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19982..20479)
                     /locus_tag="KRL22_000022"
     CDS             complement(19982..20479)
                     /locus_tag="KRL22_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH1270552.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20594..21304)
                     /locus_tag="KRL22_000023"
     CDS             complement(20594..21304)
                     /locus_tag="KRL22_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HBH1270553.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21480..22010)
                     /locus_tag="KRL22_000024"
     CDS             complement(21480..22010)
                     /locus_tag="KRL22_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270554.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKPIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEIVKNVDCN
                     IVQYSDKDERRVKAKANKMVMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(22027..22257)
                     /locus_tag="KRL22_000025"
     CDS             complement(22027..22257)
                     /locus_tag="KRL22_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270555.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMSVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22272..23666)
                     /locus_tag="KRL22_000026"
     CDS             complement(22272..23666)
                     /locus_tag="KRL22_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH1270556.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23792..25045)
                     /locus_tag="KRL22_000027"
     CDS             complement(23792..25045)
                     /locus_tag="KRL22_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1270557.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTATYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25096..26250)
                     /locus_tag="KRL22_000028"
     CDS             complement(25096..26250)
                     /locus_tag="KRL22_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1270558.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(26809..27378)
                     /locus_tag="KRL22_000029"
     CDS             complement(26809..27378)
                     /locus_tag="KRL22_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1270559.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27581..27808
                     /locus_tag="KRL22_000030"
     CDS             27581..27808
                     /locus_tag="KRL22_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH1270560.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(28027..28770)
                     /locus_tag="KRL22_000031"
     CDS             complement(28027..28770)
                     /locus_tag="KRL22_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH1270561.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            28938..29810
                     /locus_tag="KRL22_000032"
     CDS             28938..29810
                     /locus_tag="KRL22_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1270562.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            29810..30475
                     /locus_tag="KRL22_000033"
     CDS             29810..30475
                     /locus_tag="KRL22_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH1270563.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30496..31353
                     /locus_tag="KRL22_000034"
     CDS             30496..31353
                     /locus_tag="KRL22_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1270564.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31509..34055)
                     /locus_tag="KRL22_000035"
     CDS             complement(31509..34055)
                     /locus_tag="KRL22_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1270565.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMINGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYTSSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIVKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34055..34741)
                     /locus_tag="KRL22_000036"
     CDS             complement(34055..34741)
                     /locus_tag="KRL22_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1270566.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(34824..35813)
                     /locus_tag="KRL22_000037"
     CDS             complement(34824..35813)
                     /locus_tag="KRL22_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1270567.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(35800..36486)
                     /locus_tag="KRL22_000038"
     CDS             complement(35800..36486)
                     /locus_tag="KRL22_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1270568.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(36986..40192)
                     /gene="carB"
                     /locus_tag="KRL22_000039"
     CDS             complement(36986..40192)
                     /gene="carB"
                     /locus_tag="KRL22_000039"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBH1270569.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(40385..41434)
                     /gene="carA"
                     /locus_tag="KRL22_000040"
     CDS             complement(40385..41434)
                     /gene="carA"
                     /locus_tag="KRL22_000040"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH1270570.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(41692..44898)
                     /gene="carB"
                     /locus_tag="KRL22_000041"
     CDS             complement(41692..44898)
                     /gene="carB"
                     /locus_tag="KRL22_000041"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBH1270571.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGIGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(44951..45994)
                     /gene="carA"
                     /locus_tag="KRL22_000042"
     CDS             complement(44951..45994)
                     /gene="carA"
                     /locus_tag="KRL22_000042"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH1270572.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(46020..46736)
                     /gene="pyrF"
                     /locus_tag="KRL22_000043"
     CDS             complement(46020..46736)
                     /gene="pyrF"
                     /locus_tag="KRL22_000043"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBH1270573.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            complement(47112..47747)
                     /locus_tag="KRL22_000044"
     CDS             complement(47112..47747)
                     /locus_tag="KRL22_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HBH1270574.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAGGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(47771..48685)
                     /locus_tag="KRL22_000045"
     CDS             complement(47771..48685)
                     /locus_tag="KRL22_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270575.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            49286..50515
                     /locus_tag="KRL22_000046"
     CDS             49286..50515
                     /locus_tag="KRL22_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH1270576.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(50720..53101)
                     /locus_tag="KRL22_000047"
     CDS             complement(50720..53101)
                     /locus_tag="KRL22_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HBH1270577.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPIVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(53073..53798)
                     /locus_tag="KRL22_000048"
     CDS             complement(53073..53798)
                     /locus_tag="KRL22_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HBH1270578.1"
                     /translation="MGNNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(53788..54243)
                     /locus_tag="KRL22_000049"
     CDS             complement(53788..54243)
                     /locus_tag="KRL22_000049"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBH1270579.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(54525..55706)
                     /locus_tag="KRL22_000050"
     CDS             complement(54525..55706)
                     /locus_tag="KRL22_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1270580.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSIISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLVTNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(55696..56388)
                     /locus_tag="KRL22_000051"
     CDS             complement(55696..56388)
                     /locus_tag="KRL22_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1270581.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(56522..57238)
                     /locus_tag="KRL22_000052"
     CDS             complement(56522..57238)
                     /locus_tag="KRL22_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1270582.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            57363..58097
                     /locus_tag="KRL22_000053"
     CDS             57363..58097
                     /locus_tag="KRL22_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBH1270583.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIATLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            complement(58382..59233)
                     /locus_tag="KRL22_000054"
     CDS             complement(58382..59233)
                     /locus_tag="KRL22_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1270584.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDSIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKSFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(59259..60197)
                     /locus_tag="KRL22_000055"
     CDS             complement(59259..60197)
                     /locus_tag="KRL22_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH1270585.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(60300..60950)
                     /locus_tag="KRL22_000056"
     CDS             complement(60300..60950)
                     /locus_tag="KRL22_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1270586.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            complement(61099..61287)
                     /locus_tag="KRL22_000057"
     CDS             complement(61099..61287)
                     /locus_tag="KRL22_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH1270587.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(61394..62578)
                     /locus_tag="KRL22_000058"
     CDS             complement(61394..62578)
                     /locus_tag="KRL22_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1270588.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESVVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(62720..63637)
                     /locus_tag="KRL22_000059"
     CDS             complement(62720..63637)
                     /locus_tag="KRL22_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HBH1270589.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            complement(63659..64387)
                     /locus_tag="KRL22_000060"
     CDS             complement(63659..64387)
                     /locus_tag="KRL22_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1270590.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            complement(64583..64783)
                     /locus_tag="KRL22_000061"
     CDS             complement(64583..64783)
                     /locus_tag="KRL22_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270591.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            complement(64908..65288)
                     /locus_tag="KRL22_000062"
     CDS             complement(64908..65288)
                     /locus_tag="KRL22_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1270592.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            complement(65561..66919)
                     /locus_tag="KRL22_000063"
     CDS             complement(65561..66919)
                     /locus_tag="KRL22_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1270593.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            67367..67819
                     /locus_tag="KRL22_000064"
     CDS             67367..67819
                     /locus_tag="KRL22_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HBH1270594.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            complement(67976..68593)
                     /locus_tag="KRL22_000065"
     CDS             complement(67976..68593)
                     /locus_tag="KRL22_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBH1270595.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(69016..69828)
                     /locus_tag="KRL22_000066"
     CDS             complement(69016..69828)
                     /locus_tag="KRL22_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1270596.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLDEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            complement(69904..71322)
                     /locus_tag="KRL22_000067"
     CDS             complement(69904..71322)
                     /locus_tag="KRL22_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBH1270597.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
     gene            complement(71806..72723)
                     /locus_tag="KRL22_000068"
     CDS             complement(71806..72723)
                     /locus_tag="KRL22_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HBH1270598.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWATCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
     gene            72985..73362
                     /locus_tag="KRL22_000069"
     CDS             72985..73362
                     /locus_tag="KRL22_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1270599.1"
                     /translation="MLTPYLIFNGDCEKAFNFYAEAFGGGKTIFARLDSNPNNPVMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            complement(73518..73967)
                     /locus_tag="KRL22_000070"
     CDS             complement(73518..73967)
                     /locus_tag="KRL22_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1270600.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(74143..74547)
                     /locus_tag="KRL22_000071"
     CDS             complement(74143..74547)
                     /locus_tag="KRL22_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HBH1270601.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEVIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLVCGETTVNDGHCHKFLFTTQIEAPLV"
     gene            complement(74660..75526)
                     /locus_tag="KRL22_000072"
     CDS             complement(74660..75526)
                     /locus_tag="KRL22_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH1270602.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            complement(76096..76440)
                     /locus_tag="KRL22_000073"
     CDS             complement(76096..76440)
                     /locus_tag="KRL22_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBH1270603.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            complement(76629..77246)
                     /locus_tag="KRL22_000074"
     CDS             complement(76629..77246)
                     /locus_tag="KRL22_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1270604.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            complement(77251..79413)
                     /locus_tag="KRL22_000075"
     CDS             complement(77251..79413)
                     /locus_tag="KRL22_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBH1270605.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISNIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            complement(79755..82262)
                     /locus_tag="KRL22_000076"
     CDS             complement(79755..82262)
                     /locus_tag="KRL22_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1270606.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            complement(82740..83372)
                     /locus_tag="KRL22_000077"
     CDS             complement(82740..83372)
                     /locus_tag="KRL22_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HBH1270607.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNAKKIREIIKNIRKI"
     gene            complement(83478..84383)
                     /gene="dapA"
                     /locus_tag="KRL22_000078"
     CDS             complement(83478..84383)
                     /gene="dapA"
                     /locus_tag="KRL22_000078"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH1270608.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            complement(84388..84987)
                     /locus_tag="KRL22_000079"
     CDS             complement(84388..84987)
                     /locus_tag="KRL22_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1270609.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            complement(85045..86316)
                     /locus_tag="KRL22_000080"
     CDS             complement(85045..86316)
                     /locus_tag="KRL22_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HBH1270610.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            complement(86343..86630)
                     /locus_tag="KRL22_000081"
     CDS             complement(86343..86630)
                     /locus_tag="KRL22_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1270611.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            complement(86645..88732)
                     /locus_tag="KRL22_000082"
     CDS             complement(86645..88732)
                     /locus_tag="KRL22_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1270612.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMDDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNGHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            complement(88683..88838)
                     /locus_tag="KRL22_000083"
     CDS             complement(88683..88838)
                     /locus_tag="KRL22_000083"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270613.1"
                     /translation="MKLKTIKFSNKISIVEVMKESNDNMKTNLNEKVGVNGSGQRNCI
                     NSPDFIK"
     gene            complement(89147..89668)
                     /locus_tag="KRL22_000084"
     CDS             complement(89147..89668)
                     /locus_tag="KRL22_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH1270614.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            complement(89730..90536)
                     /locus_tag="KRL22_000085"
     CDS             complement(89730..90536)
                     /locus_tag="KRL22_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1270615.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            complement(90640..91434)
                     /locus_tag="KRL22_000086"
     CDS             complement(90640..91434)
                     /locus_tag="KRL22_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1270616.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            complement(91966..92820)
                     /locus_tag="KRL22_000087"
     CDS             complement(91966..92820)
                     /locus_tag="KRL22_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HBH1270617.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            complement(92852..93364)
                     /locus_tag="KRL22_000088"
     CDS             complement(92852..93364)
                     /locus_tag="KRL22_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBH1270618.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     IFSKDRKKGN"
     gene            complement(93357..93581)
                     /locus_tag="KRL22_000089"
     CDS             complement(93357..93581)
                     /locus_tag="KRL22_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270619.1"
                     /translation="MNEKSSFKQIEVILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIVIKLLEIRQAREATNYNIGNG"
     gene            complement(93641..94594)
                     /locus_tag="KRL22_000090"
     CDS             complement(93641..94594)
                     /locus_tag="KRL22_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH1270620.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIETLTKEKQAGVSLG"
     gene            complement(94622..96010)
                     /locus_tag="KRL22_000091"
     CDS             complement(94622..96010)
                     /locus_tag="KRL22_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270621.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFTPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            96283..97164
                     /locus_tag="KRL22_000092"
     CDS             96283..97164
                     /locus_tag="KRL22_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1270622.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            complement(97352..98344)
                     /locus_tag="KRL22_000093"
     CDS             complement(97352..98344)
                     /locus_tag="KRL22_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBH1270623.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIGIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(98349..99089)
                     /locus_tag="KRL22_000094"
     CDS             complement(98349..99089)
                     /locus_tag="KRL22_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBH1270624.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLIGVLSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNYSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            complement(99154..100263)
                     /locus_tag="KRL22_000095"
     CDS             complement(99154..100263)
                     /locus_tag="KRL22_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBH1270625.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            complement(100281..101414)
                     /locus_tag="KRL22_000096"
     CDS             complement(100281..101414)
                     /locus_tag="KRL22_000096"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBH1270626.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQAKQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYEVKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            complement(101416..102510)
                     /locus_tag="KRL22_000097"
     CDS             complement(101416..102510)
                     /locus_tag="KRL22_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH1270627.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNEYQVVFNVVAEEKTSEVEKTIMVNEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNKNLFKRGDVVIGNNDFGKYKGELQLILQDCTDERK
                     NKVGRIKEDEIILLDFIEPWSKFKIILEGE"
     gene            complement(102647..103948)
                     /locus_tag="KRL22_000098"
     CDS             complement(102647..103948)
                     /locus_tag="KRL22_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1270628.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            complement(104172..104873)
                     /locus_tag="KRL22_000099"
     CDS             complement(104172..104873)
                     /locus_tag="KRL22_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1270629.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKETIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            complement(105086..105403)
                     /locus_tag="KRL22_000100"
     CDS             complement(105086..105403)
                     /locus_tag="KRL22_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1270630.1"
                     /translation="MDEKIIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            complement(105451..105762)
                     /locus_tag="KRL22_000101"
     CDS             complement(105451..105762)
                     /locus_tag="KRL22_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1270631.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            complement(105911..106390)
                     /gene="rlmH"
                     /locus_tag="KRL22_000102"
     CDS             complement(105911..106390)
                     /gene="rlmH"
                     /locus_tag="KRL22_000102"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBH1270632.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKYKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            complement(106458..108560)
                     /locus_tag="KRL22_000103"
     CDS             complement(106458..108560)
                     /locus_tag="KRL22_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HBH1270633.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSILFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILSITSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            complement(108573..109370)
                     /locus_tag="KRL22_000104"
     CDS             complement(108573..109370)
                     /locus_tag="KRL22_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1270634.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDISNVYEMK"
     gene            complement(109472..110935)
                     /locus_tag="KRL22_000105"
     CDS             complement(109472..110935)
                     /locus_tag="KRL22_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HBH1270635.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNLDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFNVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            111060..112118
                     /locus_tag="KRL22_000106"
     CDS             111060..112118
                     /locus_tag="KRL22_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBH1270636.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            112127..113119
                     /locus_tag="KRL22_000107"
     CDS             112127..113119
                     /locus_tag="KRL22_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1270637.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(113502..113576)
                     /locus_tag="KRL22_000108"
     tRNA            complement(113502..113576)
                     /locus_tag="KRL22_000108"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113542..113544),aa:Thr,seq:tgt)
     gene            complement(113610..113685)
                     /locus_tag="KRL22_000109"
     tRNA            complement(113610..113685)
                     /locus_tag="KRL22_000109"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113650..113652),aa:Val,seq:tac)
     gene            complement(113690..113764)
                     /locus_tag="KRL22_000110"
     tRNA            complement(113690..113764)
                     /locus_tag="KRL22_000110"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113729..113731),aa:Glu,seq:ttc)
     gene            complement(113771..113846)
                     /locus_tag="KRL22_000111"
     tRNA            complement(113771..113846)
                     /locus_tag="KRL22_000111"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113811..113813),aa:Lys,seq:ttt)
     gene            complement(114172..115461)
                     /locus_tag="KRL22_000112"
     CDS             complement(114172..115461)
                     /locus_tag="KRL22_000112"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBH1270638.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            complement(115543..115851)
                     /locus_tag="KRL22_000113"
     CDS             complement(115543..115851)
                     /locus_tag="KRL22_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270639.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            complement(116056..117384)
                     /gene="dnaB"
                     /locus_tag="KRL22_000114"
     CDS             complement(116056..117384)
                     /gene="dnaB"
                     /locus_tag="KRL22_000114"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBH1270640.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            complement(117403..117852)
                     /locus_tag="KRL22_000115"
     CDS             complement(117403..117852)
                     /locus_tag="KRL22_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBH1270641.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            complement(117853..119847)
                     /locus_tag="KRL22_000116"
     CDS             complement(117853..119847)
                     /locus_tag="KRL22_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBH1270642.1"
                     /translation="MSNKQAFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            complement(119858..120814)
                     /locus_tag="KRL22_000117"
     CDS             complement(119858..120814)
                     /locus_tag="KRL22_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HBH1270643.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            complement(120822..121142)
                     /locus_tag="KRL22_000118"
     CDS             complement(120822..121142)
                     /locus_tag="KRL22_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH1270644.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            complement(121285..121512)
                     /locus_tag="KRL22_000119"
     CDS             complement(121285..121512)
                     /locus_tag="KRL22_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBH1270645.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            complement(121531..121965)
                     /gene="ssb"
                     /locus_tag="KRL22_000120"
     CDS             complement(121531..121965)
                     /gene="ssb"
                     /locus_tag="KRL22_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH1270646.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            complement(122002..122280)
                     /locus_tag="KRL22_000121"
     CDS             complement(122002..122280)
                     /locus_tag="KRL22_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBH1270647.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            complement(122494..123690)
                     /locus_tag="KRL22_000122"
     CDS             complement(122494..123690)
                     /locus_tag="KRL22_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1270648.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            complement(123793..123978)
                     /locus_tag="KRL22_000123"
     CDS             complement(123793..123978)
                     /locus_tag="KRL22_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBH1270649.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            complement(123993..124256)
                     /locus_tag="KRL22_000124"
     CDS             complement(123993..124256)
                     /locus_tag="KRL22_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBH1270650.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            complement(124329..124931)
                     /gene="yedF"
                     /locus_tag="KRL22_000125"
     CDS             complement(124329..124931)
                     /gene="yedF"
                     /locus_tag="KRL22_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBH1270651.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELNNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            complement(125036..126328)
                     /locus_tag="KRL22_000126"
     CDS             complement(125036..126328)
                     /locus_tag="KRL22_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1270652.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSESKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            126588..127163
                     /locus_tag="KRL22_000127"
     CDS             126588..127163
                     /locus_tag="KRL22_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HBH1270653.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            complement(127296..128438)
                     /locus_tag="KRL22_000128"
     CDS             complement(127296..128438)
                     /locus_tag="KRL22_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH1270654.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVINPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(128471..129334)
                     /locus_tag="KRL22_000129"
     CDS             complement(128471..129334)
                     /locus_tag="KRL22_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBH1270655.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            complement(129336..130109)
                     /locus_tag="KRL22_000130"
     CDS             complement(129336..130109)
                     /locus_tag="KRL22_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBH1270656.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            complement(130244..131029)
                     /gene="noc"
                     /locus_tag="KRL22_000131"
     CDS             complement(130244..131029)
                     /gene="noc"
                     /locus_tag="KRL22_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HBH1270657.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            complement(131192..131911)
                     /gene="rsmG"
                     /locus_tag="KRL22_000132"
     CDS             complement(131192..131911)
                     /gene="rsmG"
                     /locus_tag="KRL22_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBH1270658.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            complement(131904..133796)
                     /gene="mnmG"
                     /locus_tag="KRL22_000133"
     CDS             complement(131904..133796)
                     /gene="mnmG"
                     /locus_tag="KRL22_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBH1270659.1"
                     /translation="MKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSIA
                     LMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQADK
                     FKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVYL
                     NSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMSL
                     QEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPRY
                     CPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLENC
                     KIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINAV
                     RKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLTQ
                     KGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGISL
                     YEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLEN
                     KKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRRT
                     RGGKGE"
     gene            complement(133894..135273)
                     /gene="mnmE"
                     /locus_tag="KRL22_000134"
     CDS             complement(133894..135273)
                     /gene="mnmE"
                     /locus_tag="KRL22_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBH1270660.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            complement(135385..136014)
                     /locus_tag="KRL22_000135"
     CDS             complement(135385..136014)
                     /locus_tag="KRL22_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HBH1270661.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            complement(135983..136690)
                     /locus_tag="KRL22_000136"
     CDS             complement(135983..136690)
                     /locus_tag="KRL22_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBH1270662.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            complement(136722..136973)
                     /gene="yidD"
                     /locus_tag="KRL22_000137"
     CDS             complement(136722..136973)
                     /gene="yidD"
                     /locus_tag="KRL22_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBH1270663.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            complement(137005..137349)
                     /gene="rnpA"
                     /locus_tag="KRL22_000138"
     CDS             complement(137005..137349)
                     /gene="rnpA"
                     /locus_tag="KRL22_000138"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBH1270664.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            complement(137427..137564)
                     /gene="rpmH"
                     /locus_tag="KRL22_000139"
     CDS             complement(137427..137564)
                     /gene="rpmH"
                     /locus_tag="KRL22_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBH1270665.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            138220..139542
                     /gene="dnaA"
                     /locus_tag="KRL22_000140"
     CDS             138220..139542
                     /gene="dnaA"
                     /locus_tag="KRL22_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBH1270666.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            139784..140890
                     /locus_tag="KRL22_000141"
     CDS             139784..140890
                     /locus_tag="KRL22_000141"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBH1270667.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            141027..141233
                     /gene="yaaA"
                     /locus_tag="KRL22_000142"
     CDS             141027..141233
                     /gene="yaaA"
                     /locus_tag="KRL22_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBH1270668.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            141251..142366
                     /gene="recF"
                     /locus_tag="KRL22_000143"
     CDS             141251..142366
                     /gene="recF"
                     /locus_tag="KRL22_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBH1270669.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            142367..144268
                     /gene="gyrB"
                     /locus_tag="KRL22_000144"
     CDS             142367..144268
                     /gene="gyrB"
                     /locus_tag="KRL22_000144"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBH1270670.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMIAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            144288..146714
                     /gene="gyrA"
                     /locus_tag="KRL22_000145"
     CDS             144288..146714
                     /gene="gyrA"
                     /locus_tag="KRL22_000145"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBH1270671.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            146783..147079
                     /locus_tag="KRL22_000146"
     CDS             146783..147079
                     /locus_tag="KRL22_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1270672.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            147079..147339
                     /locus_tag="KRL22_000147"
     CDS             147079..147339
                     /locus_tag="KRL22_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBH1270673.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            147351..147668
                     /locus_tag="KRL22_000148"
     CDS             147351..147668
                     /locus_tag="KRL22_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HBH1270674.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYILNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            147693..148079
                     /locus_tag="KRL22_000149"
     CDS             147693..148079
                     /locus_tag="KRL22_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1270675.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            148079..148852
                     /locus_tag="KRL22_000150"
     CDS             148079..148852
                     /locus_tag="KRL22_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HBH1270676.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
BASE COUNT        48370 a        26021 c        16854 g        57717 t
ORIGIN      
        1 ttaaggacaa gtaatactat atcatcttaa aaatgtttcg tcaatacttt ttttgttttt
       61 tattttaaaa aaggttataa cttttggttt ttttaataaa tataattaaa actaatagat
      121 ataacccttg atattacaaa caatacatgc atatataatt ttacctattt tgcaatttta
      181 ttttcataag aatatgaatt agctctcact ctatctgccc aaacatttat actcttaact
      241 ttattaacat tagttgtacc ctcaaaaata tccattgcat ccttacaaaa atatatcata
      301 acatcaagaa ccaaaaatcc aacacaaaat aaacataaaa aattaattac ttgaaacatc
      361 agacattccc ccaataattt tttatatata gtattctcat aaattattct ttttaccttc
      421 tcataaatta ttctaaatat tttcataata aattactttt aatcatattt tctaaatata
      481 aagtctcaat caacaaaaac taatatcaat ttctaacgtt tgttggtaat ttataaatta
      541 aatatctaaa agaatctttg aagcatataa aaagcattcc acactgacat tttaaataaa
      601 atttagctat ttattgataa tttaatagct aaactttatt taaaacttag tagaatgcta
      661 atatttctta gttttcttct tctttatttg gattgttatc aataggtttc atagtcggga
      721 ataataatac atctcttata gatggagagt tagttaataa cataattact ctatctatac
      781 ctattcctag tcctcctgta ggaggtagac ctacctctaa tgcttttaag aaatcttcat
      841 ccatttcaaa agcttcatca tcacctaatt ctctttttct caattggtct ataaatcttc
      901 ctttttggtc aatagggtca ttaagttcag aaaatgcatt agctaactcc cacttattag
      961 caaatgcctc aaatctatca gttcttcttg ggtcttcaac atttctctta gataatggag
     1021 atacttcaac tggatggtga gttataaatg ttggttggat taatttatct tctccaaatt
     1081 cttcaaagaa agcatttatt acttctcctc ttctcattcc aggttttatc tctatacctt
     1141 tttctctagc aacttctagt gcctcttcat ctgtatttat agtagaaaaa tctacaccag
     1201 aatattcttt aacacaatct tccatactca ttcttttcca aggtggtgta aagtttattt
     1261 ctgttccttg atagttaact atcatacttc ctgtagcaac ttcagccata tgtgcaataa
     1321 cattttctgt tatttccatc atatcagtat agtctgcata tgcttgatat aattctattg
     1381 cagtatattc aggattatgt tttaaatcca taccttcatt tctaaacatt cttcccattt
     1441 cataaacttt atcaaatcca ccaacaataa gtctttttaa atacaattca ttcgctattc
     1501 ttaaatacat tggtatatgt aaagtattat gattagttat aaatggtcta gcatttgccc
     1561 cacctgctat agtatttaat attggagtct caacttctaa aaatcctcta tcatctaagt
     1621 atgctcttaa tgcttttaat gcttttgttc taattaaaaa agcatttttt acttctggat
     1681 ttactattaa gtcaacatat ctttgtctat atcttagttc ttggtctttt aatccatgat
     1741 atttttctgg taaaacttgt aaagatttac atagtaatac tacagattta gcctttacag
     1801 atatttcacc ttttttagtt ttaaagattt ctccttcaat tccaactata tctccaatat
     1861 catatgttga aaatacacta tattcttcct ctcctatagc atctagtctt acataagatt
     1921 ggattcttcc ctcttggtct tgaatatcta taaagccagc tttcccttgt attctcttgc
     1981 tcattatacg tcctgctatt tttgtagttt taccctcaag agaatcaaag ttatctttta
     2041 tatccataga ataatgagtt ctatcatatc tactttcttt aaaaggatct ctacctgact
     2101 cttgtaattt ttttagttta tctcttctta cttgaagtac ttcactaagg tcttcttgaa
     2161 tttgcgcttc ttcattgctt tgttgattat ttttcatttt tttcctccaa attatcttct
     2221 tatttctaat atttcaaact tagcaactcc atcaggaact tgcacttcca caacttcttt
     2281 cgcagctcta cctaaaagtg ctttccctac aggagattcg tttgatattt taccatcata
     2341 tgggtctgct tctgtcgaac caactatagt atattcaacc tcttcatcaa attctaaatc
     2401 cttaacttta actattgatc ctattgtaac aacattaagg tctattttgc tttcatctat
     2461 gataacagct tttctaacca tattttctaa ttttaaaatt ctttcttcaa cttgtgcttg
     2521 ttccttttta gcttcatcat actcagcatt ttcagataaa tcaccaaaag atatagcaac
     2581 ttttattctc tctgcaactt cttttctctt tacaaccttt aagttttcta attcttcttc
     2641 taatttatca tatccctctt gtgtcaataa aaactcttta ttttcttcca ttataaatac
     2701 aactccttca caaatttctt aggaattttc ctaattatat tttaaaaatt ttataatctt
     2761 tttttaattt atgcgctata ttataagtca ctattatttt tatgtcaagg agtcttccat
     2821 atagtactcc aatttcgaca caacttcttg atagtcttct attttgttaa tttcatccct
     2881 taattttgca gagtttctaa gtccttttaa ataccaagcg atgtgttttc tcatttccct
     2941 tacagctaca tactctccat gttcttctac tgcaagtttt aaatgcttaa tggcagtact
     3001 tattttttcg ttaagagttg gctctggcaa aatctcgcct gtattcatat aatggtttat
     3061 tcttttaaat atccaagggt taccttgagc acccctacct atcattatag catcacaacc
     3121 agttttgtct aacatattta ttgaatcttc tattgtaaat acatcaccat ttcctataac
     3181 aggtatactc aaatttttct taatctctgc aattatatcc cagtctgctt tgcctgtata
     3241 aaactgttct ctagttcttc catgtattgc taaagcactt attccacaat cctctgctat
     3301 ctttgctatt tcaacagcat ttacactatt atcatcccag ccttttcgaa tctttaaagt
     3361 cactggcttt tttgagttct tcactactgc cctcaatacc tcttctgcaa gcttaggatt
     3421 tttcataagt gctgaaccat ctccattttt aactactttt ggagctggac accccatatt
     3481 tatatcgaga atctcatttg aataatcatt cattatctct gctgctcttc ccataaactc
     3541 gggttctgaa ccgaatatct gaactgctac aggatgttct tcctcttcta tcttaagcat
     3601 ttttttagta ttttcatcat catagcaaag tgccttacca tttatcattt ctgtatataa
     3661 aagcccacat ccctgttctt tacaaattaa tctaaatgga aggtctgtta cacctgccat
     3721 aggtgataga aaaactttat ttttcaattc taaatttcct attttcattg tttttctcct
     3781 atttttgcct ttattttgtg atttaacttt aaattcttat ttcctcatta taatatacca
     3841 catatagcta gaaatctatc ataaaaaggg aattggatat ataacccaat tccctgtata
     3901 ttaattattc ttggtttttt tcatatatta ttctcaatcc ttctagtgtt aaaaaaccat
     3961 ctacataatc tatacttttc gtctctgaag caatcagttt agctaatcca cctgtagcta
     4021 taaccttaac atcatcacaa ttcaattctt tcttcatcat acttattatt ttgtcaacta
     4081 aaccaacata tccataaatt attccagatt gcatggctga tacagtactc ttacaaatag
     4141 tcatacctgg cttagctaat tctactctag gtaatttaga cgcactttga aataacgcct
     4201 cactagatat ttttattcct ggtgctattg ttccacccaa atattcacct ttttcagaga
     4261 tagcacaaaa tgtagttgct gttccaaaat caacaagtat acttggtgct ccatactttt
     4321 ctatccctgc tacagcatta actattctat ctgccccaac ttgttttgga ttatcatatt
     4381 ttatatttag acctgttttt atgcctggac ctactattaa tggttgtttt ttacagtact
     4441 ttatacaaaa gttttcaaga gaatgcataa cattcggaac tacagatgat attataacat
     4501 catcaatatc acttatattc acattatcat aatcaaatag gttacttatc aggattccat
     4561 attcatcaga cgttttttcc ctatctgttt taattctcca gtaattaact aatttgtcac
     4621 ctttatatat acctaaaacc atattagtat ttccaacatc aaatactaga agcatatgtc
     4681 attaaccttc tttctatttt ttgcttttct taagtacagt ggcaacagca gctactacta
     4741 aagcccctac tattgcttct ggcaccccat ttgctgcggc aagagccatt attacttttc
     4801 ctgctgaacc acttttaccc attgcatgaa gatacttgtc agcatataag acatatatca
     4861 ttcctaaaac tccagctgta tttaacagag aacctattgc ccctgtaatt aaacctgata
     4921 tgtatacctt atttgtagcc ttaattatta actgatatac ataataagct aatacaccta
     4981 tcataactct tggtaatatt gaaactaatg gatttataaa aacaaaagat gttactgttg
     5041 ggtttgttat agcatttaag agacttgata tcccaaatat aaatcctatt gctgccccaa
     5101 ctattggtcc ttccataata gctccaataa taactggtat gtgcattata gttgcttttg
     5161 taggtccaac tggaataaat cccaatggag tcatagatag cataatagaa atagctgata
     5221 gtactcctat tatagtcatc tttcttacat ttacttttct tactgatgca cttgtgttca
     5281 tcataaaaaa tacacctccg ttccagctca ttaagatgcc ggactactta attttttaat
     5341 ttttttcgtt tttttcttat aactatgagt caagctacca ttgtaggatg cccgctctaa
     5401 caagaataat tttatcaaga tgagttgcca ttgtcaacaa tttgacaaga aaaatatgct
     5461 aatttcatca tatttctcgt ttttttacta tatctttata tgccattata ttttctacac
     5521 tatccgcttt ttttactgca tttattatac ttttttccac aacctctaca gccaatgaac
     5581 ctactaatgt tatatctgct tctatttctc ctgttgatat tgtgaatatt gtatctccat
     5641 catgaggtgt atggatagga aaaatagact tagcatatcc atcatgtccc atttgagata
     5701 tctttttaca tccagctttg gttaacttag catttgttgc aattatccca attgtagtat
     5761 tatctacact aaatccacct ttactttcac cttgtttcat taatttatat gtatcaattg
     5821 tttctgtctt tttatcattt aaagcaccag ctataacctt accattttca taaacatctc
     5881 caagagcatt tacagcaatt aatgcagata caactagacc attatctaat tttatagaat
     5941 agctacctat tccgcctttc atagcatatt cctgacctct tatctttcca acagtggctc
     6001 cacaacctgc tccataattt ccttgattta aaatatcagt atttgcaact tcacaagctc
     6061 tataacccat ctttaaatct ggtctacatt taaagctccc tactcctaaa tcaaataaaa
     6121 ctgctcctac aactataggc actttaccta cacctacatc aaagccaatt cctttttctt
     6181 ctaagtatct acttacacca caagtggatt caagaccata tgcagaacct ccagccaaaa
     6241 ctactgcatg aactttttga accatattta cagggtctaa taaatcggtt tctctagtcc
     6301 ctggagcaga gccccttaca tcaacaccgc aagtagctcc ttcttcacat attactactg
     6361 tgcacccagt aagaccattt ctatcctcaa cctgcccaac ctttaagcct tctatatcca
     6421 aaatattatt atacatatcc tttttctcct cttatagaaa cttcacctga aataatttct
     6481 tttatacttc catcacttct ttgaactaat aaatttccct cttcatttat gtctaaacat
     6541 ttcactagtt ctctattatc tccttttaat acatatatat ttttatctat aattgcagaa
     6601 taatctctac atatttttaa ggttttttct ttggaattat ttacagtata atctaaatat
     6661 aatttttcaa attcagtcaa tacattccta acaatatcta ctctggataa catatatcct
     6721 tctttataca atgatgtggc tttgtcagct atttcttgtt caaaatccat tattttaaca
     6781 tttattccaa ttccaagaac aacataattt gttctttcaa tttcagcaga taactctgtt
     6841 aatataccac atattttttt tccatttaaa ataacatcat ttggccattt tattaatgta
     6901 tttgctccta gattgtttaa agctttcgtt acacttgctc ctgctattaa agttataaat
     6961 ggggctttga atggttccat atctggtttt aatataatac tcatccagat tccttcatga
     7021 ggttttgaat cccatcttct tcccaatcgt cctttcccca tatcttgatg ttcacttaaa
     7081 atcacagtcc catctacact atttatagct atccttttag catgttcatt tgttgaatct
     7141 atagtgtcaa gatgttcaat attttttcca ataaactctg tatctaattt atagtaaata
     7201 ttctgtgggc ttaataaatc agttggattt tccgctaatc gatacccttt tttatttaca
     7261 gattctatat tatatccctc ttcttttaag gctttcatat gtttccatat agctgcacgt
     7321 gacaccccta attgttttga taattcttct cctgaaataa attcagattt attatttaat
     7381 ataatctcta ttattttatc tctcatattt cacctctaat atgacataat ttcatgactt
     7441 attttcttct aataaataat tatacattat taatatactt ttaatactat taattttaaa
     7501 tttccttttt aattattata atggttgttt tatattttat attgatgatt tatataattt
     7561 tacattttat ttaaataatt ttaaaataat aaaaaaactg aaagtatcaa ttaaattaat
     7621 acatgcaaat ataatttgct tattaattta atattatact ttcagtttta gtatttaatc
     7681 cacatcagat aataatccta aaatgaccaa ggtcttaaaa ctatttatct ttatcagatt
     7741 tatcttctaa atttttattt atatcaataa cattgtttct ttcttcttca tctttttcta
     7801 attttatagt taattgttct tcaacttctt tagaagaatt ttcctctgta actgcatttt
     7861 caatttcatt cagaggtaac tctttattaa atgcttttac aaattgttct gcatctaaag
     7921 tttcatatat aagtaaagct tgtgctacat actctaatct atccatattt tcttgtaata
     7981 tacttcttgt cttatcatat gcaccatcaa ctatacgctt tgtttcttgg tctatctcaa
     8041 aagcaacttc ttcagaataa tttctcttac ttgaaaaact attacctagg aatacttcat
     8101 catcactgtc aaatgacatt ggaccaagtt tagaactcat tccatacttt gttaccatac
     8161 ttcttgcagt agctgtaact ctttctaagt catttgaagc acctgtagat acatccttaa
     8221 gtactagctc ttctgctact ctaccaccaa gtaaaactac aatattttct ttcatttcat
     8281 tttttgtagc atagaactta tcttcaacag gaagttgcat tgtaaaccct ccagctcttc
     8341 ctcttggaac tattgtaact tgatgaacag gacttacttc ttcaagtaca tgggcacaaa
     8401 ctgcatgccc tccttcatgg tacgctgtaa gtcttctttc tttctcactt attactttcg
     8461 attttttagc cacacctgct ataacctttg ttatagcttc ttctatagtt tccatcttaa
     8521 ttttcttttc tctttttcta gctgttaata ttgcagcctc attcattaag ttctctatat
     8581 cagcaggagt aaatcctggt gttcttctag ccaagacatc catttttaca tcatcactta
     8641 atggtttatt tcttgagtga actttaaata tagcctctct accttttaca tctggtgtac
     8701 caacaacaac ttgtctgtca aatcttcctg gtctaagtaa agctgggtca agtatatctg
     8761 gtctatttgt agctgccatg attattatac cttgatttac cccaaatcca tccatttcaa
     8821 ctagaagttg attaagagtt tgctctcttt catcatgacc tccaccaaga cctgcacctc
     8881 tttttctacc aactgcatca atttcatcta tgaatatgat agctggagca cttttcttag
     8941 cctgttcaaa taaatctctt actcttgaag caccaacccc aacaaacatc tcaacgaaat
     9001 cagaaccact tatactgaaa aagggaactc ctgcttctcc tgcaactgct cttgatagat
     9061 atgttttacc agttccagga ggtcctacca taagcattcc ttttggtatt cttgcaccca
     9121 attcaatata tttcttagga ttctttaaga aatctactac ctcctgcaaa tcttcttttt
     9181 cctcatctag tccagctaca tctttaaatg taactctagt tttttcatca tctttatgaa
     9241 ccttagcttt tgatttgcca aaactcataa cctttccgcc tccaccttga gactgattca
     9301 taaacacgaa ccaaataatc accatgaaga atattaacag taatgtaggc aacatttcga
     9361 caaaccaagg tgtagatggc ttagcttcac caccaaaagt tagtttccca gccttagctt
     9421 ggtctaacac ctcatctgca agtttatttc ccatcacttc tgttggaaca tatgacttaa
     9481 actttgtatt tgtatctttt atagtacctt ctacagaagt ttgatttaca aagtataatc
     9541 ttgatatatt ctcatctgtt aattctctgt atacttcaga gaattttaaa tcttttattt
     9601 tttctgtagg cttacctgag aattgaacta tacctactat aattataaaa acaagtagat
     9661 aaaaacctgc cccttttagc aacttattca atatagaagc cctcctttca tacattgctt
     9721 tgccctataa tttgttaaaa ttaattttta atacttcttt tgtgttttca tcaattttat
     9781 aattttcact gattttataa tctccaacac atattattcc ttcactatct gtgattatag
     9841 gaattttaca tctttcttct cttgggattt ttaaatctat gaataaatct ttcacttttt
     9901 tacttcccat agcaagcttt atcttatcac cttgccttct gcttcttatt actatacccc
     9961 cttttacctt attaaaatca aaccctttag atgaattgtc taatttcata ctcttatacc
    10021 tatctatgct cattacttgg gtctcaataa tttgttttaa ttcttttatt ttaataaacc
    10081 cattactagg tacattgtaa taaaattcaa tttcctcatt aacaatttcc tcattcgtta
    10141 atattatact gtcttttttt ctataaacaa atatatttct tggaagagtt aacattttat
    10201 ttacttttga attatcttct aaagacatta tatcctctat atgtctttgg tcaacaaaat
    10261 tagtatctcc tagtatatgt tttatggaat ttctaagaac tctaactttg atagcatcat
    10321 gtaagcaaac aaaatcgtct aaatttatct ctacaaagcc tttttctttt atatttgaaa
    10381 cttctctaaa tttagcttct gcctctttct caatataatc gttatcactt tttaaactat
    10441 tgctcatcct cactatagat tctattacat ttgaattaaa attatccttc atatatggta
    10501 aaaggtctaa ccttatctta tttctagtgt atatattttc taaatttgtt ttatctatcc
    10561 tcggatttaa attataagct tcacaatact cctctatctc atttctttcc acgtctaata
    10621 tgggtctaat tatgcaatta tctctaatat aatcaattcc ctttaagcct tttaaacctg
    10681 ttcctctcat gatacgcatc ataaccgttt cggcttggtc attgagatta tgacctattg
    10741 ctattttatt ggctttaatc ttatccttaa tttcataaaa catttcatat cttagcttcc
    10801 ttgctccttc ttctaatgat aatccctcat tttcacaata ttttggtaca ttaatagact
    10861 ttacaaagaa tataattccc atatcctcac aaagtttaga tacatataat gcatcttttt
    10921 gagcttctat ccctcttatt tgatggttta aatgtgctgc atatatttct atattaaaat
    10981 ctttttttaa tctatttagt acatgcaata aacaaactga atcaggtcct ccagaaagac
    11041 ctaaaactat tttatcgcct ttttgtatta aattatgttt atttatagta cttagtacct
    11101 tatcaaatat catatttatc cctcttacac ttagttttat tcacttttaa gtatactttc
    11161 tataaaaaaa cgctaaaccc ttgtatcaat tttaagaaat taaagtttaa tataaatata
    11221 ataataccaa ataaattaaa taaaaggtaa ttttttcact acctttataa aatttctgga
    11281 aaatagccat agttattatt tagtacctat gtatatatct attttattcc tacctaaaaa
    11341 taaatcttgt acctttatat tatagtctat tttcaatttt atgtgttccc cttcttgtat
    11401 atttatatct aattctcttg tatcaatatc aattaataaa gtaccttgtg gggtcacata
    11461 ctttgtagta ctactttctc cacatttaaa cagcattgtt gagttaatag caccaaactt
    11521 tttgatacta acttgatttt taagtatctt tatagtatta gttatttcta tatcttcttc
    11581 tttttccttg taaataacat atattccatc atttttataa aaaattttac caaaggcagt
    11641 catctctatg gtgtccatat ttcctttttc atcatattgt ctagtattta tacttatttt
    11701 tacactcaac gatttttcct ccatagattc ttcatataaa ctagtatttt tgtatttcta
    11761 ctttttgaat cttatcaatt tttttcttta agaactctct tgctatatct gaaaattttt
    11821 caggtatatc tgatacataa tattgataag ttccatgaat ttctgtattg tttataatat
    11881 tttgcacctc taaaatcttt tttaaatcct ttgcagtctc tttagctgga ttaacaagtt
    11941 ttatatgctc tccaacttct tcacctattg ttctctttaa aataggataa tgagtacatc
    12001 ctaacactaa agaatctata tttttttctt tcaattcttg taaatatatc tttgctgtca
    12061 gtttagccac ttctgtattt gcccatcctt cttcaacaat aggcacaaat aaaggacatg
    12121 ctttattaac aatttctata ctctcatcta ttttagatat ttccaagttg tatgcttttg
    12181 aacttatagt tccttcagtt cctattattc ctacaatttt gttttttgta gaacttacag
    12241 ctgttctagc tcctgcttct ataactccaa ttatcggtat atcatatttt tcttgagctt
    12301 cttttaagct tcttgcagta gcagtgttac atgctataac tatagctttt acaccttttg
    12361 tttttaaaaa gtttatagct tgaaaagtat atttaattat agtttctttg gatcttgaac
    12421 catatggtat tctggcagta tctccaaagt atattatatc ctcatttggt aatatcttca
    12481 ttatctcttt tagaactgtt aatccaccta atcccgaatc aaaaactcct attggtttat
    12541 tgttcatctt tatacaacac ctactttaca tttttgtgtt taacaacaac ttatttatcg
    12601 ctaaaattta tatttatatt cataattaat atattattac ctaaatgatt attatagttt
    12661 attttacaca aaaaataaag gagctatctt aaattagaaa ataatttcta caaaaagaca
    12721 actcctttca ctacttaaaa atttaaattt attttgcaaa cacatgattt cctattctca
    12781 tataaggatt caatctattt atccatttgc aagtggctat ttctggattc caaaaatata
    12841 ctgctttatt agttgggtca gttccataaa gagcttcctg agctgcttta cgtgctgagt
    12901 ctgttggtgc catctttatt gaaccatcaa gcacaactga gaaagcattt ttttgatata
    12961 tgacttcttc tattgtgtct ggaaatctag ggtccaatac tctatttatt actacagctg
    13021 ctacagcaac ctgtccctca tagctttctc ctctagcttc tcctgcaacc aacttagata
    13081 ataacatcaa gtcattatca gataaattta ttacttcttt ctttgctata tttttttctt
    13141 gtttgtttac tttcttaata ttttctgttg gttcatatgc aaatacttct ttaataggca
    13201 taaatataaa agtcaaagct aatagtgtag ccatcagttt actccacctg tccatgatta
    13261 aaaccactcc ttacattctt atttttaaaa ttttttctct aaatccttga ctacttcaag
    13321 tactttaaac ttaattttta ctctacttgt tttttttggt gtatcttgtt ttattaactt
    13381 atattcttta tcagttaaaa cttccttcaa cttatcatct gtagatttat ctatcactcc
    13441 attagattca tcaacaaaac atagtggagg gaacataaca caccaccagt tttttccttc
    13501 acctttccca ataataatct ttaatgcttt atattcacca gctggaagaa ctatattaga
    13561 atattgttta gtagggaaat tgctatattg tatacctacc tttacactgt aattatatcc
    13621 atttttaaga ataatatttt tacttatttc ttccagacta ctatattcct tttttataat
    13681 agcttcactt tcttttatac tttttgaatt ttgaagcttt ggctgtaaat attttattac
    13741 ttcatctcta acttttagtt taagttcttg gtcttcatct gtattgctgt ttgctataac
    13801 atgaaatctt attaatttat ctttataatc ttttgatata ttgtctactt tttttacctc
    13861 accatttatt actattgtca ttattgatat gactgatata agacttaata ttaatagtcc
    13921 caatctaatc ttaatttttc tcattgaaaa ttccccctca agataaattt atatcatcaa
    13981 ttatgtccaa ttaaatttaa tttattcata atatttttta atactaataa aaaaagctat
    14041 cttaaaatga ttacaatcat tttaaaatag ctttttaaac cttatatttt ataagtcttt
    14101 actaatcata gccttatcta tcataaactg ctctgctttt tctatatgct ctgtagcata
    14161 cttcttggat agctcactat cacctttaat tatagcatca agtaaatatt tatgctcttc
    14221 aacaatatta tgtgatgtat cataagcaga catataggta actctaaatc tatatacttg
    14281 ttcccacaat gagtttatta attggattaa ttttttatta ttagttgctt taaatataca
    14341 ttcatgaaat tctacatcaa gttttaataa cgcatctaca tcggattcca aagtgctttt
    14401 tttaaattct tctgatatat ctttaagctt tttaatatct tcatcactaa ttctttcagc
    14461 ggcaagatat gctgctaagc cttctaggct tgctcttact tctaatacat ccataatatc
    14521 ctttaatgac atatttgcca catacgcacc ttttctaggc aacataacga ctaaaccttc
    14581 taattcaagc tttcttattg cctctctcac tggagtccta cttactccta attgttctgc
    14641 tagttgcact tccattagcc tttgaccagg ctttaatttt ccttctaaga ttgcttctct
    14701 taaattctca aagactacat ctcttaatgg cttgtaatta tccaagttca gtttagttaa
    14761 attctccaca aatttcaacc cctttttgac tgctattaac aacatacacc tgtttatatt
    14821 tttttaataa ttcttttttt ccaattagag catcttcttt atttttaaat agtccaaaaa
    14881 ctgtaggacc acttccactc atcatagaac ctaaagcatt atttttcatc attacttgtt
    14941 ttatatcact tatttctttg tgtttaccta tagtaacatt ttcaagaata tttaccatgc
    15001 tttctgatac agcttttata tcttcagatt ttaaacactc tatcaaatat ttattatttg
    15061 gtcttttttt aatattattc aaatctaatc cttgataaac ttctttagta gaaacgaata
    15121 agtctggttt gcatatcaat atatttgtat cacatggtaa acctttgata tttgttagct
    15181 tttctccaat accttgagct aaggcaggtc ttcctgatat acaaaaagga acatctgcgc
    15241 ccaaattaag tcctatttct tttaattcat cttcagataa tctaagttcc cataggtgat
    15301 ttaaacctac taatactgcg gctgcattag aacttcctcc agccatccct gctgctacag
    15361 gaatattttt ttctatgaat atttctacac ctttttttat ataaaattta tttttaagta
    15421 ttttggcagc tttataaaca atattatctt catctaaagg aatatctaaa ctagtgcttt
    15481 ttacctttat ttcatcttcg tctaattctt ttatctttac tatatcgtat aaatctatcg
    15541 tttgcattat catttcaaca aaatgataac cgtcttgcct ttttcccaag acatcaatgg
    15601 ataaatttat ttttgctcta ctctttagtc ttataaaatc cattctatcc tccttgttta
    15661 aagaataatg catcactaac aataatatta tactacaaaa aataaaataa tagggtatta
    15721 taatacccta ttatacttaa ttactttaaa ttttttaata ttaatctact aatacgactt
    15781 ttttttctaa aataagacac ttaccaggct taattggttc atcaagtttt atatcattaa
    15841 gttctgcaat ttcattttct gttgtattgt atttttttgc tatattccag aaagtatctc
    15901 cttctttgca tatatatacg attatgctag gagctttaga taaatcatat acaccttggt
    15961 cttctccctt gataataaaa ttttctgctt tcttatctaa tgcttcagta aatctcttaa
    16021 ttttgataat caagtctatc tggtccctat tcaaatcaac ttcgacttta tcaatacatg
    16081 ctgtattaaa cacagatgct gtatcagtta gattatccat ttctatatca tgttcaaatg
    16141 gaatttcctc actaatttta taaactaatt ttaaaccttc aactgggaca aataaaattt
    16201 caacttttat gattccttgt ataatgcttt tatttccttc aatataacta ttttctatag
    16261 acatggttgg acaaacgctt acaatatctt ttatttgtat atcatcatta tcatttctta
    16321 tgccttctct aaccataaat gtttcttcac tacgtcttaa agtcttattt aattgaatag
    16381 gtttgtggtc aaattttatt atcttttgag gcgaatatgc atcttgtaat acttctcttg
    16441 taacttcatc tgtaactttt accttacaac aagccataca atctatttct aaaagacctg
    16501 tgttgctttc actattttgc ttgaaaatat gattaaaatc tgacatagac aacaatactt
    16561 cttcagtcat accatcacta actccaggga cttctacaaa ttgagtaaac tcaataccta
    16621 ctctatccaa ctctacaagt tcaccctcat atgtacaagc taacggattt atttctaata
    16681 ctccaccaat aataacttta ttgtcagtca ctctactttc ttttacttta acacatggat
    16741 ttaaacttat tatagattga atttcctctg tgtttattgt tatagtatct cttatagaac
    16801 tttctgcttt ttctattcca actatatctt gaaaacaaat ttcctttctg tgcttttgta
    16861 tgccttccac ttgcgccaca tcttttacaa tgtctaacct ttgcttttca aacaaacttc
    16921 cccttatatt cataagagct cctactttaa tctttctctc attcattata gtacaatcca
    16981 tatgctctac ttctgaaaat aacatgtatt ccatatcttg aataacattg tctttttcta
    17041 ttacttcgtt tatatctact tttccgtcta cattagaaat agtattttta tcatctgcaa
    17101 tatagattac attataatta aaactacctc tgcaaagtat cttcccatct gccatttcaa
    17161 tttttttaag tgatatgtat ccttctgttt ttacaatttc atatacatct aattttttgt
    17221 ctggcacaac tgcctccgct tcaatgaatg tttgaaattt tccaaagtct attctattgt
    17281 caactttaat tacatcttta attaattcca tagtctacct ccttaagtat tataaaaata
    17341 tcacactata tttatattta aggagcaaaa aaaaaattac acctattttt aaataggtat
    17401 aattttaact tatttgtaat ttatcttgat ctctaaaaac ttgcaacttt acattagatg
    17461 ttaataaatc tgagtaacta taagatactc taggatatcc attactttca tcatctaact
    17521 ttataacaaa cacgcttgga taaacttttt ctagtatacc ctcttttgta ataatctgct
    17581 ttcttccttt attagctttc aacaatattt tctttcctat atgtctctct aagcttactc
    17641 ttatcttatc tagagtttga acagtagcca caatatcacc ttctttaacg tttatatgtt
    17701 tacataatat cacatataaa catttttgtc aaatgtttaa actaattatt ttatatattt
    17761 tttgcaaaaa tgtcaatact atttttgaag atatacagta taattatgtt aatttttgct
    17821 aatgtaatat tgtttttggc attgcccatc taaattttcc tcttgtttca gaaccaccaa
    17881 ttcccttaac acctgtaata gtctgctcta taacctcatc aataggaact actacatcaa
    17941 ttcttgaaca agcaattttc tccactataa aaacagggtc taatgcatgt atcattattc
    18001 ttccaggtga acttgcatag tttgctcctg cacttattat tttttcataa tttgattggc
    18061 atgctcctgc gaatatgaca agattatcca aatttggttg ccatttacgt gcttctttta
    18121 ctgttttaac aaaatttgaa gagtttctat agttactcat atcttctata tctcctcttt
    18181 ttattgtcat tgcatcatga cctgttatta ctagtatatc cggattatat ttttctagta
    18241 gtgctcttac ttctttatac tgattttgct ctgaaacagc tacacctact gcaggtattc
    18301 caagttgagc atatacatcc aagcaaattt ttaaatattc tttatctcca tctatctgta
    18361 gtacttttcc aggcattcca tatgtgttag gatttaattg aagttttgga actgctctag
    18421 tcattctttt ttgtctttct ttagcttttc ttactgactt atataataaa ttttctacat
    18481 ttttatctat taatatatct tttatatcag gtgcttttac taattctagg tcatcaatat
    18541 aagcatctgc tattactcta aatgcaattc cctttagtat agctattttc tcattatttt
    18601 catctacacc aaaagagact attttaaata ctatatcttt gttatgtgac tttctagcta
    18661 caatgtctcc taccttcata gttaaacctc caataaattt ttatcttagt ttatactatg
    18721 ttcgatataa aactttgttt cctaatgtca aaaaaacatt tcttataata cttcttttat
    18781 cactcttaaa gcatttttat agtatatctt ttctatatca tcttcactaa acccttcttt
    18841 ttttagaggt tcatacagtt tacccatctg agatatatct tcaatctcaa cttttgaatc
    18901 tattccatca aaatctgacc ctagagatac aacatctatt cctccaacat ttacaatatg
    18961 ttttatgtgt ctaaccatat cttcaagttt actttcactt ttatcactta aaaataagtg
    19021 gaagaagttt atacctgtaa ctccaccttt atttgctaat actttaatca tatcatcagt
    19081 taaatttcta gaatgattca tcattgctct tgaattagaa tgtgtagcaa ttattggttt
    19141 agaagaaatc tttgcaattt cataaaatcc accatctgaa atatgagaaa catcaaccaa
    19201 cattcccaat tcattcatct tatgtaccac ttctcttcca aaatcagtaa gccctttttc
    19261 tctatattct actttattat gaggaaagct caattcattc acatgattcc aacttattgt
    19321 catcattcta acccctaagt cgtaaaattt ctttaaattt tctaatttac cttcaagtac
    19381 tgcaccttcc tcaatagata aaagagctgt aagtttacct tctgattggt ttttcataat
    19441 ttcttcatag ttagtagcta aagctatttc atcactattt tttttcattt cctcatgaaa
    19501 tttatttgcc atactcatgc aataatcaaa aggatgtttt acttcttcag tatcaacaaa
    19561 aagagcaaat gtttgagcta atgaatcccc ctttttcaat ctgtctatat caacagaata
    19621 tttattagac ttaagttcac ttgtttctac attttccatt aattttgcta tagtatcaca
    19681 atgtaaatca ataaatttca tatttatacc ccctgtatat tttatattta tatctaaaaa
    19741 tagaaatagt tgtccttata gacaactatt gacaactatt ttttaatatt ctttttaata
    19801 ttacttaatc ttattcttct tttaagttag gtattacttt tttaacttct tcaatttgat
    19861 gccatgtttt atctatatta ttttcactaa tatatttttt taaatcagtt aaagatgtaa
    19921 aatctttaac tgataaattg tcatcatcat ctgcaaatct taaaataaac atgagactcc
    19981 cttactttcc acaacatttc ttatattttt ttccgcttcc acatgggcat gaatcatttc
    20041 ttcctatttt tgcttcttta actattgttt tagacttctt ataagccttt attatttctt
    20101 ttctttggtc tgctggtagt atatcttccc aaccttgtaa attatatagc caatgagcct
    20161 caacagttac catattgtta tataattttt cccaatctat ttttatagaa acttctttat
    20221 cagcttctac ttcttctaaa actatatctt cttttaagct ttcacttatt ccatctatga
    20281 atcccatgaa aaattcatta gtagttccaa atttttcagc caattcactt actttacctt
    20341 caacaacatc cattttatta tttaatattt cattgtatat tccagcttca actttcaaat
    20401 attcttccca gaattttact tctgcttctt gactttcatg attatcactt aaatttctcc
    20461 attcagtata taaactcata ctttttcctc ctaagtatac ctatattttt atagttttta
    20521 tagtataaaa tcttttagtt agattggaag tttcttcttt ttgattatac catattctat
    20581 ttaaagttaa ctcttatatt atatcataat taaacaattc ttttaatact tttatagcat
    20641 actcttggtt tataaaataa gggcttgtcg caattgttat tactttggct tttttaatta
    20701 agttttttat cttgtaaaat ttgagttcaa atggtatata gtccatatca cttgaaaata
    20761 tatccaaatc tatatcaaga acaaactctg attctacttc taaatcaaat ccatatagac
    20821 tatctattat tattaattct gaaaatatgt tatattttaa agcaggtttt ataaaacttc
    20881 ctacatttaa aacttcattt gtatatctaa atacatcttt tagattattt acatctacat
    20941 catagttctc aggttctcta gtatccttat gttggtctac atgcactaac ttgcatcctt
    21001 ttgtaaactc accctttaac aaagattttg cccaaaaata aaatgcatgg ttatgattgt
    21061 caaacacata tatcttttta tttcccagga catattcgac catattctcc aatccttttg
    21121 cttttatttc cttattttca tctacttcat taaatactac ctcattgcct aaccttacat
    21181 catttaatgt accatttatt agttttggaa cgtatatgct cttattttct cttttatcat
    21241 atgaaaatac attatttcct actggttttt ctatataaaa tccactatat tcataatttt
    21301 ccataaaact ttatttcctc cattgttata taaatatata agttataatt ttaaaaatta
    21361 aaatgcactt attgtaaatc atatcatcta ttatagaaaa catcttatat aactaaatat
    21421 aatatcttct ctcaatatgt attatacaat aagtgcaaaa tatatttata taaaatatac
    21481 tacattccta taacaaaacc atcagcttca attggaaggt aactaactct tctattcaac
    21541 tccacctttc caaaaaatac tacccaatat ggtctaaaaa tactttcaat tttaactatt
    21601 tcaatctctg ggattcctcc cataaaccta tgagttaatc tcataaccat tttatttgcc
    21661 tttgctttta ctcttcgttc gtccttatca ctatactgca caatattaca atccacattt
    21721 tttacaattt catatgtagg aaaatcttgt actatactac cagaacctgt agaaccattc
    21781 actaaaattt ttaattcatt tatatcatta gaatatctcc tattcttgaa aatgggtttc
    21841 gttttgtgaa ttttaagtgt gataatttta aactctatat aatgaagtct aacttcatga
    21901 gcatatttgt tctttaatat tagcttacta aataaagaat tttttccact tttagctatc
    21961 tctatagctt cttcttttgt aattcttata ggtaacgctc ttatatccat aaaatcattc
    22021 tctttcttat ttttttcttg tcatttttaa aactctatat atataatcaa aaaatattac
    22081 aattacaact gacataactc catatggaat tatttttcca actataatat catttctagt
    22141 caatatacca taaaatataa atcctgttat taaaaagtac aataatacta gaaaaccgtc
    22201 tattccaagc cattttattt ctaaatcttt ttttacctta gacactaatt tagacatagc
    22261 agtttctcct tttatagatt attttgtgta tttaaatttt cacctattct attaccaatc
    22321 atccatgcaa taaatgaaaa aggtatagct atcacaagag gctctaactc aaagctctga
    22381 actggaaata ttttaaaata accaaaagtc actccaccaa caatcattcc taaaatacca
    22441 cccatagatg ttcttcttcc atttccaaga agcccaccta ctataggtac aaatgccgaa
    22501 cccatccaaa tacttcctac aaatatacat gcatcatata cattttcaaa tctaaatgct
    22561 acgctaagcc ccataactgc tgctaaacat acacctattc tagtaaactt tactaattgt
    22621 ttctgagata actctttttt tgtaattctt ccatatatat catttgctaa tgtagcccca
    22681 gctgctagat aatagctatc caatgttgat attatagaac ctaaaattcc tattataaat
    22741 attactctta ttccttgtgg taatgtatct aaaactaaag ttatatatcc agcagctgga
    22801 gccatttctg gataagtagc tcttactata agtcctgtca tagttaacac catgtcaaaa
    22861 catatccata gtgaaaaaca agttaataag gctcttcttc caaccttagg agaatctgct
    22921 gctgaaaatc tttgataaaa agttgggtct gaataagctc caaaagaata tacaattaac
    22981 atcaatgctt tcatagctga catacctttt gtagggtgca taagctgtgg tgcatctttg
    23041 agtgcttctg taagaccttg aaaccctcct atttgttcaa attgacctgg cataaccata
    23101 gttaaaccaa ataccataca aaaaaacaat accatatctg taatggcaac tcccataagc
    23161 ccaccaagta ctgtaagtac aacgactact cctaccatta ttaatcctat taattcttta
    23221 tctattttcc atgctacgtt acctatagtt cccatagcag ttatttctcc aagttgtgca
    23281 caatatataa acatcaaaat tgccccaatt atagcaacat gcttgccata aaaactttcc
    23341 agtaaatcag gaactgttat attggttctt atatgaatcc ttggaccaac ccacaatgct
    23401 aaaggcattc tcccaatatg tgcagctatt gaccaaactg cccatgcaga tattccatat
    23461 atagctgcat actctacact acctactgta ccaactcctc cataccatga tgcaaccaaa
    23521 gttcctacta ttaaggacca tggtaaactt cgatttccta ggtaataact ttccatatct
    23581 tttacatttc tagaaaaata ataacctatt cctaataata taaatgcaaa tataactata
    23641 atcccatttt cccaaaatgt taacatatct aatctccaca ttcttatatt ttaattttta
    23701 actttaatat ctaaatatga acaactctac ccatttccat aaaaataggt agagttatat
    23761 aataattata agtatttaag taatcttgtt attaagcaat tttattgttt aaacctttat
    23821 tttctctttt atttatttta tttaaagcat aagtagcaaa tatccctata actgcacata
    23881 ctacagataa aataaatata tatgtatatc ctgtttgtcc atatttatct aaccaattac
    23941 ctgcaatagt gtaataaaac gcatctggag aaaatcctat aaatgaagca aatccaacta
    24001 ctgctcctgt agtttctaaa gatatattag actctgaaac agatgcaaag tatatacctc
    24061 taaatccaaa taaaattaca cttagtatta tcatgtttat tacagctatc catataaatc
    24121 ctgtactctt aggaataacc aagtaagtag ctgtacttac tgtcattaat ataaatccta
    24181 caaacattac tcttatagat gaaccaactt tatctgttat aacaccagca actggagatg
    24241 ctcccatttt tataacataa gttcttatta ttgataaagc agaaactaga gtcattggca
    24301 ttacataaac ttctgataag tatggactta aataagttaa acttgagaat actaaataag
    24361 ttgaaaatat tataagacca attaaccaag cctttggcat tgtaactact tttaacaatg
    24421 acttaatact taatccttca tctgatgctc cactatcttt tttctcttct actaagaaaa
    24481 atagaagtat accacatatt atagatgctg cagaatataa ccatactaca tatttgaatc
    24541 ctactgttat ttcagcaaat ttaccaaaga aataaagacc tataaaagaa attaatgtac
    24601 ctgatacgcc tgataaccct tcataaaaac caaatattct tccttgctct gactcacttc
    24661 cttgcattct aacaacctta acagaggctg agaagaaggt taatattgtc gtaaatcccc
    24721 ataatacaaa tattaaaagt atcatactat atgatgggaa tgtagagaaa taaaatccaa
    24781 gtattcctga agcaattaaa gaaaaagtta ttaattttct aactgagaat ctatctgcaa
    24841 accatcctcc tataaaataa gataccattc ctactaatcc atataaactc aataagttcc
    24901 ctatttgtgt atgacttaat gctaaagctt gttgcattgg gtcataaaat gatgatttca
    24961 tatatggtaa actatacata gctgttgttc caaatgccaa tatgaatatt atcaaaaatc
    25021 ttttaacatt atttttgctt tccattgatt ctctctcctt aaaattttat tgtttataat
    25081 ctcattcata taattttatt ttaatttttc tattgcttgt ttaaaatcat ttattatatc
    25141 atttgaagat tctaatccta cagctattct tattagattt tccccattca tttgaactaa
    25201 tgtatgctct tcccctaagc ttgttgctat tgttgcaagc tctaaagaat tcattaatct
    25261 tctactagct tggtctcttg tcaatccatt gataccatcc ttaagtttaa atgaaactac
    25321 acctccacct aaaccattca tttgagtttt acaaagctca tattgaggat gagattttaa
    25381 tgctggatac tttaccaatt ccacattctc ttcttcctct aaaaattctg ctactgctaa
    25441 tccattttca caatgctttt tcatcctcat atctaacgtt ttcatacccc ttaaaatcat
    25501 ccatgcactc attggtggta aagatgctcc tgtaaaacaa cataaacttg gccatctaac
    25561 taaatctatt aattcttttg aacctgctac tgctccccct aaagtatccc catgtccatt
    25621 tataaactta gtaagactat gtattactaa atctgcacct aaatctattg gtctttgtac
    25681 aattggtgtc ccaaaagtac tatcaactat agctaagctt ttattttcat gagcaatttc
    25741 tgctattgtt tttatatcta ctaagtctaa tgatggattt aaaggacttt ctatataaac
    25801 tattttagta tttggtctca ttgcttcttt tacattttgt ggatttactg catctacaaa
    25861 tgtaacttca actccaaatt tagataacaa ctcagacatg aataatttag tgtgtgaaaa
    25921 tattccatct gaactaacta tatggtcacc actttttacc aatgctaata tagtagaggt
    25981 tattgccccc atccctgatg tactagatat ggcactttct gcattttcaa gcatagccaa
    26041 cttagcttct aactctgtaa gagtaggatt acactctctt gtatacacat atccccatgt
    26101 catacacaac tcttcaaaat gctctactgt ctttgcagca aatgttgctg tttgacatat
    26161 tggtgtagcc aatgcacctg ttgttgggtc tgcactatgt ccccaatgta ttatttttgt
    26221 ctctaaatct tgattaatat tgttactcat tttgatttcc tcccattttg acttatttat
    26281 acaacgtttt ccctgccaaa tttcatcaat ttagcttagt cttaatacat tttttcaagt
    26341 atactttttt atttgttata atttctaaaa atatgacact tattttgttt tttacagttc
    26401 taattataaa ctctatagta actatagagt caatatgttt ttgatatttt ttttacaatg
    26461 tttaaaatag tcagtacaaa aataggtata tcttagaata actaaagtca tcctaagata
    26521 tacctatttt tatatcacaa tataaataat tacatataag cattagtttt tttatcataa
    26581 atagattttt caagatttat catcttttca taaatatatt atagttaaat attttaatat
    26641 tacctaacat ctacaataaa atatactctt aaaataaaat tatataatta aaaatactct
    26701 ataaaagcta aaaagttttt ctattcgcta catctaaaaa taattagata gaggtataaa
    26761 tgtatttagt ttatttatac ctctagtctt ttataaatta tatctctact aaattgattt
    26821 tttagcacga ataagtgtgc tcttggagat accagtcatc ttcacaacct ctctatatgg
    26881 cttagaattt aataacccca atgcatattg tatctgttga ttgctgtatt tctttggcct
    26941 accatcttta aagtcctttt tctttttagc aaattctttt cctaattgag tacgttctat
    27001 tatcatattt ctctcaagtt ctgcaactgc aagtaatgta gtcaaaaaga atttacccat
    27061 tgaagtattt tctaaaaggc ctatatttaa aatatgaaca cttacttctt tagcaaataa
    27121 accttctatt agttgtattc cttctgatgt acttctagct agtctatcca gcttagttgc
    27181 aacaagtaag tctccctttt ttagagatga tataattttt tcaaatttag gcctgtttgt
    27241 agtagtgcct gtataagttt cctttattat tttagcatca ttatatttat tcaaaatttc
    27301 ttgctgttgc tgatacaaac tgttgttgtc tgtttgattt tttgtactta cacggcaata
    27361 tccatatata ataatcatca cttcctaaca taaagatttt gtacagaagt tacccagaag
    27421 cttgttttta cttatcttta tccattttac taaaacgatt tttgggtgtc aatactgtta
    27481 acttttgaca ccataataat tcctttataa tttgtttgac tatgtcaaaa attaccaata
    27541 taatgaaatt aatgagttta tacaaattgg aggaaataat atgaatagtc tgttaaaaga
    27601 agcaatagat gaattaaaaa acatccattg cggggaagtt tttttattaa aagaattgtt
    27661 caaaggctat gaatggaaca ggttggagat gaatatcaga ttgaaattag gaaaactttt
    27721 tttgtatgaa gtggtaacta atcccaattt aaatgtagag gtcatcaata aaaactctgc
    27781 ttatcagcaa atgtataaaa aaaaatagtg acttaaatgt atataatagt ataatcttct
    27841 tattgattca aaagttaaaa cttttaatac aaaacaatca ttctatttta acatttatca
    27901 atatgtctaa atttatataa ttaacacata cgaatagtat tgtttaaatc acattattta
    27961 agatagataa atcttaaccc tactccagca taaatactaa aatagggctt agaattatct
    28021 atatttttat cccataaaat gcttagctct tcctcttgat tgaacatata tatctgggga
    28081 aatacaatag aagcgtaaat ttataaaatt tccaaagtca gaaaacttca gttcaaactt
    28141 aggtatacca aaactttcag gtgctatttc gtcaacacca aaatagatga taattccatt
    28201 atctgtaaga taaaatgctt ggtcttcagg tataactaac tcaacattag aataatacat
    28261 ttctctattt tcatttattt gagatttaat gtaatcagta attatgttaa tataatcaac
    28321 tccatctcta aaaatgtcat taagtaaaag ttcttttcca gttgtcaaat ctatattgta
    28381 attattcaat gtattgtatt taggcccata gttattagca aaccccataa ggtttaatat
    28441 catactcagt acataatttt tattaaaagt aactgcgtaa ctggtagata cccaatagct
    28501 ttgttttgga agtgaatttt gagaagctgc gttattatat tctcgttctt cttcctgtaa
    28561 gccattttta aaattattta cagtcattct tacagcattg tttatgttat ttaaaataac
    28621 tgggtttaca tacgtggatt gatttctaat attgtatata acaggatact ttacatcata
    28681 tgaaaaatac ttacttcttt caaaatcttc attaaattgt acatataata tattatatgt
    28741 acaggtattt gtagattgat aattttccat taaaatcctc ccccttttat aaaaaaatca
    28801 gatacaatat aatatgctta aaacagtaat aatgttaatg gtaaatgtaa agaatagaaa
    28861 gtatctaaaa cagcaaaaaa tgactaattt tgtggtataa tacataggat tgagagttat
    28921 tttataggag gaaaaatatg ttattattag cagataaatg gaaagattat gaacttatag
    28981 atatgggaaa tggagaaaaa ttagaacgtt ggggaagtta tgtacttaga agaccagacc
    29041 cacaggttgt atggccaatg gaatctgaat gggctttatg gaaaaaccct catggacatt
    29101 atcacagaag caataaaggt ggaggtcaat gggaacacaa aaaaagatat ccagaacaat
    29161 ggactataaa ttataaaaac ttaaagtttc acattaaacc aactggcttt aaacatactg
    29221 gattattccc agagcaagca gctaactggg attggatgat agagaaaata aagaaagcta
    29281 acagacctat aaaagtgttg aatctttttg catatacagg tggagctact gtagcatgtg
    29341 catctgctgg tgcagaagta tgtcatgttg atgctgcaaa aggtatggtt aattgggcaa
    29401 aagaaaatat agaattatca ggtcttaaaa atcaaacagt aagatttata gtggatgatg
    29461 ttgtaaagtt tgttgaaaga gaaataagaa gaggtaaaaa atatgatgca ataataatgg
    29521 accctccttc ttatggaaga ggtcctaaag gagaagtatg gcaaatagaa gaaaagttat
    29581 acagttttgt agatttatgt atgggagttt tatcagataa ccctttattt ttcttaatta
    29641 attcttatac aacaggattt tctccaatag ttcttgaaaa tgtattgtct acaacaatag
    29701 gtaaaaagac aaatacagga gatatatacg gtggggaatt aggaatacca gcttccagag
    29761 atggtaagat acttccttgt ggtatatttg gaagatggga gaaaaaataa tgataaaagt
    29821 catatatgaa gataaccatt tattagttgt agaaaaacca gttaacatat tgtctcaagg
    29881 agataatact aatgataaag atatggtaaa tcttttaaaa gactatatta aaaaaaagta
    29941 taacaaacct ggaaatgtat atattggttt aatacataga ttggatagac cagtaggtgg
    30001 agttatggtg tttgcaaaaa catcaaaagc agcatctaga ttgtctgagc aggtaagaag
    30061 taagactttc aaaaaaactt atctagctgt tgttcatggc aagataaaat ctaactcaga
    30121 tatactaaaa gattttttat ataaaaataa aaaaactaat atggtaactg tagtgaaaaa
    30181 aagccataaa gatgccaaag aagctgaact taactataat gtattagatt ttaaagaaaa
    30241 tctaagttta gttcaagtta atttaaagac tggtcgttct catcaaataa gagttcaatt
    30301 tgcaagcaga aaacatccat tatacggaga ccaaagatat ggcaaagaaa taaataaaat
    30361 tggacaacaa atatctcttt ggtccaataa gatagaaatt tgccatccta ctacaaaaga
    30421 aaaaatggaa tttacatgtc atccacctga caaatatcca tggaatatat tttaaatctc
    30481 aaatgaggtg attatatgag taaaaaattt tcaataggag aaatgtctaa acttcataaa
    30541 ataagcatac agacactaag gtactatgac caaatagatt tatttaaacc tgttcatgtt
    30601 gaccaagaaa gcaattacag atattactca attgaccaat tttcacaatt agatattata
    30661 aaatatttaa aatatttagg tatgccttta aaagaaatta agtcaaagct tgatgaaaat
    30721 aatgaagaaa ttctaaaatt actaacaaat aaaattaata tagtggatga aaaaattaaa
    30781 gaattagagc ttataaaaaa ggtactaagc acaaagaaag aaactatgga aaaaggtatg
    30841 aaagtagatg aagttggtaa aatagtgaga aaacatattc cacgaagaag tatcttatct
    30901 atagagtatg aagaaggatt aagtagtgaa gaaactatgg aactttccag aagacaaata
    30961 gcaaatatat tagaagataa tatatctgtg ttctatggtg gagtaagtgg acttgtatct
    31021 atagataaat ttttaaaaga agataaagtt atttatgaca atagttttgt tactgttgaa
    31081 agagacttat ttgatataaa atcacaaaaa catataacag aaatttcatc tggtgatttt
    31141 atttgtatga catataaagg gccttacaaa gaaaattata ccgcttttaa gaaactggtt
    31201 gattatgttg aatataaaag aatacctatt gaaaattata tatatgaaat acctataata
    31261 gaccctctgt ctacaaacaa cgaagaggaa cttctaacag aaattcaaat acaagttaaa
    31321 aagagagaaa ttgacttaag atgtctagtg tagtaatcta gtttacttac acatcttaat
    31381 atagttgtct attatcaaca tatgattttt ctagatagtg attcctaaca gtgagatttt
    31441 caaaaaatag gaggaaatat ggctaatgct aattccctcc tatttttaat taatccatat
    31501 cattttaatt aagccatgtc atcacgaagt gcatcaataa tattttcttt ttttatctta
    31561 ttaatagtat acaacattgt aataaatact ataaataaaa cactaaatat actaattcca
    31621 atactaaacc atggaatcac aaaatcaata tcatctgtaa ccattacttt atgaattagc
    31681 catgaagaaa ttactgctat aggaagtcca aagaacaatg ctctcatgcc ataaaaggca
    31741 cactcaaaat tcatcatctt ttggaaatca tgctcagaca ttcctacaga gcgaagcatg
    31801 gcaagttctc tacgacgtaa cttaatatta gttgaaattg tattaaacac attggcaatc
    31861 gaaatcagag aaatcataat tatgaaagta taagcaaaca cattggcaat aaaaatgtaa
    31921 ttacggttct catccatcat tccatacata ttgtacagat tgtactcatt cgtaactccc
    31981 tcactctcaa taatttgctc catttctgca actgactgag taggattttt cgattgaaag
    32041 cttaaacttt caattcctgt agaaacacca ggaatctcaa acttatcttt ggctgaataa
    32101 ggagccaata ctctgaagct tgctttcttc acatctgaac ttctgattcc tggaggagaa
    32161 tcaggtggca ctactttgac aaatgaaata ttcacatttt gtctctcagg tatctccaac
    32221 ttaccattag tttcaggagt gaggctaaca ttcatagaag aactgttgaa aatatcaata
    32281 atattattat cctttgttac catagaaaca gcaatcagtt ttgcattttg tccagtatat
    32341 tcttctgctg gtaatccaag acttttaata atattcagat aagttctatc atcaagaaat
    32401 tgcatatcta ctggtaattc aagcatttca ctcatagaat gtgaaccctc atagttcaaa
    32461 taatcgtctg taagctcact tactttggca acacatgaat aggtcataag tttctgatac
    32521 aaaccttcgt aaacaccatt tgcagttttt agcttatcgt aaagcttcaa catttcgttg
    32581 tctttcatac cttgtgtaga aaaaataata tcctggtcag taacctctga cctctgattt
    32641 gacatctgtt ttaggtctgc tactaaagca cttgtagata taaataaaac tatgcttaaa
    32701 acaagcgaca atacaatact tcgataacgt ttcttgtttc ttttaaagtt tttcatagca
    32761 agaactccct caagaccata aactcgctgt gttagttttg atgtcttcac agatttagat
    32821 tcaattttta cctcatttgt ctgacgaata cactccatca ctggtgtgtt ggcagccttt
    32881 cttgctggta tgtaagcaga aattaagatt gtaaccatac ttaccactgc tgcaacgatg
    32941 attgcaggga tagacaatgt taatgtcaac ggaacgttta catagagaat atttgcaaag
    33001 tttttaacta tgacagaaat cacaagtcca atactgacta taccgattgc aacaccaatt
    33061 ggtataccaa tcgcaccaat gcaaattcct tcaaatagca ccgaatttcg taactgtttt
    33121 gctgtagctc caacagatga aagtattcca aattgatgtg ttcgctcgtt caatgacatg
    33181 ttaaatgaat tatatattag aaaaattgag cctagcatga ttatggcaag cacaatgcca
    33241 ccaaccgagt acaaaaacat attgaacaaa ttgttatcag aaacacctat gaagcgtaac
    33301 acattgtcat tgaaaatgga agcatggtct ttagtgctac ttgtgtaaga gcgaatctga
    33361 tgtggatttt tcaatgtgac aaaaaggcta agactgtcag tcttgacttg tttatcttct
    33421 ttggttatca aggtatatcc tggtgcagaa gattcttcaa atacgggctt tctacagata
    33481 cccacaactg tataagtttt cttatcctgt ggcacaaaaa cttcactccc agcagtgtat
    33541 gggtcactct gaccaagctt ttcattttca ctcattcgtt tccctacatc caaagaaata
    33601 gtatcaccta ctgcaaattt gacaccacca tctgtcgcaa ctttacttga aacaagaatc
    33661 tctctactat tttcaggtaa tcttccagaa attaaagtta taggcaaagt atcaaaagct
    33721 tctttgctaa atccagcaat aaaaagatat ggtttatctg gatttctgtt accttcaagt
    33781 gttgcatagc caatattttc aaatgttgca gtatttgcaa cttcatcatt gactctttgt
    33841 tcctgtacaa aagaagaatc cacatccaaa aactggacat gccaatcacc atattttata
    33901 atagctccat ttatcatata gttcatcaaa gaaactccaa aggtagtaac tgctgtaatc
    33961 atagcagctg acagaacaac tcctataatt gttacaagag ttcgagttcg attctttttc
    34021 aatccttgca gagcaacttt gttaaaaatg ttcattaacg attcaccttc ctctcatcac
    34081 gcactacttt tccatctgaa atacagataa ttctatctgc ctgtaaagca atgttttcat
    34141 catgtgtgac aataatgaga gtttggtgat atttactatg gctctctttc agtaactgga
    34201 taatctcttg tccattttta ctgtctaagc tacctgtagg ctcatcagca agcataactg
    34261 ctggtgcatt catcaatgca cgaccaatgg caacacgttg ctgttggcca ccagaaagtt
    34321 gatttggtaa atgtgttttt cgttctttta aaccaagtaa ttctaacaag tcatttaacc
    34381 gttcttgatt gaccttacgc ttatccataa gtataggcaa tgtgatattt tctactacat
    34441 ttaatgtggg tatcagattg tgaaactgat aaatcaatcc aacttgtcgc ctacgaaaaa
    34501 tagcaagttt ttcattgctt tggccatata catcttgccc ctccagatat atctttccac
    34561 ttgttggtac gtctactcct gcaatggaat gtagtagtgt agatttacca gaaccagaag
    34621 aaccaatgat tgcagtaaac tctccttttt caatagtaag tgagacatgg tcaagtgcag
    34681 taaccttatt ttcattctta ccataaacct tacataaatc ttcaatcttt aaaaacgcca
    34741 ttatataagt ctcctttcat attttataaa tatatcatag gactttcaac ttacatttaa
    34801 gtgacattta aatgagagat tcgtcacttt ggaaaacgaa taacaaatat tgcaccacct
    34861 tgtgggtgat tttgtgcagt aattgttcct ccttgtctca taataatcgt cttacaaagt
    34921 gccaatccta ttccataacc ggctgtgctt gaatttttcc cacgataaaa tctgttaaat
    34981 agacatggta aatcttcttt tttaaagcct gctccgttgt catgaatagt aagttgagta
    35041 aacaaaaagt tgtcctcaca aatgatatca atttttccat tatcacccac actctccatg
    35101 cagtttttaa atatattttg aattgcttct gaaagccaat ttaaatcacc caaaatcctt
    35161 actccttttg gtatatcaat atgtaaagtg atattgtgca gttccatggg aatcaaaagt
    35221 tgatgaagtg cagaactaat caaattattc acatcaattt gttctttttg aaagactaca
    35281 atacctgcat ctaaacgtga taattttaaa agggaagtaa tcagccagtc cattcgtata
    35341 agtaattcct ctgtttctcg tatcaactct tttctctcat cttcatcaga agtattctct
    35401 aacagtgaca aaataagagt tactgatgta agaggagtgc gaagctggtg ggctatgtca
    35461 gctagtgagt cagcaaggtg ttctttttct tttttcaatg cgtaattttg ctctctaata
    35521 cgtaacgtca ttttagttat ttcactttgc agaatagaaa gttcaccctc atctgattca
    35581 gcaatataca gatggttagc attatgaagc acaagattaa tttgttctga aatctgtgca
    35641 atacttttgt atcgattttt agtaaacaca aaaaatgcta ttccaaaggt agtggcagaa
    35701 acaatagaaa gtattccagt cataatactg attgcaaatc ccagggctac agtgagaata
    35761 gtaattaata agaataaaat agcaaatttt cgaaactctc tatttcgaaa cataacttcc
    35821 ccccaatcta taccctgtcc cacgaacagt caaaattatt tgtggacttg aggggtcatc
    35881 ttctatcttc tctcgcaagc gtttgatgta cacagtcaat gtgttgtcat taacaaactc
    35941 acctgcagca tcccacaatt catcaagtaa tcttaccctc gtaataatac ttttaggatt
    36001 gctaataaac accaataaca aacggtattc taaagctgaa agaaaaacct cattgccatt
    36061 ctttttcaca acaccggttg ctgtatctac ataaagccca caaatttcaa aagttgaccc
    36121 aaaacgtcca ctttttcgta gtgctgttct aattcgcgca atcagttcac gtggacgaaa
    36181 aggtttagta atataatcat ctgcacccat attcagtcca gtaacaacac ttgattcatc
    36241 accagaagct gtcaaaaaga taacgggaat gtcttgcttt tctttgattt ctgtacaaat
    36301 cgtaaaccca tttccatcag gtaaagaaat atcaataagt gccaaatcaa atttattctt
    36361 agcaatctct acaagtgctt cacttcttgt ggatacatgg gttactataa atccttctga
    36421 attaagcaaa agaataagat ttttggcaat tgctttatca tcctcaacta aaaatatccg
    36481 tttcatttac tttcatcctc ctttatttta ttagttttat atattccagc agagcaatag
    36541 tacactacta ttttacttat cattacacaa ttttcagtag tttcttttgt tcttatataa
    36601 tccatgcata atacctccat tgatttatta tatttcttat aacataaata cacaagataa
    36661 gacaaaaaac ataatgtaag tgcaagtttt ttaactcact aacttataaa catacactcc
    36721 tactaacact actttcttga tgacacatct tacaagctta tattcataca tcaatgaaaa
    36781 attaaattta tccatttatt aaaataaaag gcaatagctt ctatagctaa tgccctttat
    36841 cttaaaatga tttaaatact atacaatttt tataaatggc tataaataaa ctcgtataga
    36901 atataaaatt tatctacagt cttttgttat acaaaattta taacctctta tagaacaaat
    36961 ttaccacttt gcaaacttat cacttttact cagctatatt ataaactttt aatttatctt
    37021 tgtttaaatg tttcttctta acttctacta aagcttttag cgtatccaga gatgtcatta
    37081 tttcagtaga aaattcaata gctgttcttc tcattttaaa gccatctctt gtagagtcat
    37141 ttcctttagt tggtgtattt attactatat caacttgttt atttcttata gcatctaata
    37201 tgtttggtct aggctcttca attctattta ctatatcagc ctctattcca ttttctctta
    37261 aactcttcgc tgttccttct gtggcaacaa aagtatatcc taattctttc atatcttttg
    37321 ctatctctat aaactcatct ttatcatgat tgtttacagt agcaagtact actcctcttt
    37381 catcagacat atgtctacct gctgccaaga atcctttata taaggcttct tctaaatttt
    37441 ctcctacacc tagaacttct cctgtagact tcatttcagg tcctagactt acttcaactt
    37501 tagataattt agacattgag aatactggta cttttactga tactaatttt ggctctttgt
    37561 aaactcctgt accatatcct aaatccttta atttagctcc taacatacac ttagtagcca
    37621 agtcaactat tggtactcca cttactttac ttatatatgg aactgttcta ctagctctag
    37681 ggttaacctc aattatatat aattcatttt gaaattctat aaattgtata ttaaccatac
    37741 caagcacatt aaggtctaaa gctatttttt tagtgtattc tactatcttt tcttttattt
    37801 catcagatat attttgactt ggatacattg ttgtactatc tccagagtga actccagctc
    37861 tttctaaatg ctccattata ccaggtatca atatatcttc tttatcacat atagcatcta
    37921 cttctatttc tctaccagtt agatatttat ctataagtac tggattttta tggtctctat
    37981 caaatgcatc atccaaatac tgaattagtt tttcttcgtt ataagttatt tccatacctt
    38041 gaccaccaag tacataagat ggtctaacta atactggata acctaactcc ttagcaattt
    38101 caacaccttc attagttgtc catacacctt ttccttttgg tctatttata tctagtctct
    38161 ctagtaaatc atcaaatttt tctctatctt ctgctgcatc tatatctcta aagtctgttc
    38221 ccagtatagg tatatttttt tcatgtaaaa acttagccaa ttttatagct gtttgtccac
    38281 caaactgtag tattacacct tctggttttt ctttttctat tatatttaaa acttcttctt
    38341 ctgttaatgg ttcaaaatac aacttatcag atgtatcaaa atccgtactt acagtttcag
    38401 ggttattgtt tacaattata gtttctattc ccatttttct taaagatttt acacagtgaa
    38461 ctgaacaata gtcaaattct attccttgac ctattcttat tggaccagaa cccaatacta
    38521 caacttttct cttatcacta actactacct catcatattg ttcataagtt gaatagtaat
    38581 aaggtgatag agcttcaaat tctcctccac atgtatcaac cattttataa actggttgta
    38641 tattatataa acttctcaat tcatataatt tttctgggct tatcttcatt aagtcagata
    38701 tacctttatc agaaaatccc tttttcttta attcatgtaa atattcttta tctaagtctt
    38761 ctatttttag aacttttaac ttttcttctt gttctactat ccatttaaat ttatttataa
    38821 accacttatc aacaccagtt atttctgata tcatttctac tttatagcct cttcttatca
    38881 tttcagctaa gtcaaatagt ctctcatcat caggtactac tactctagcc tttaattctt
    38941 ctaatgttct accttctgat ggagcatgaa ccaatgaata ttttcctgtt tcaagtgatc
    39001 ttataccttt aagaatagca gcctcaaagt tacttcctat actcatgatt tcaccagttg
    39061 ccatcatctt agttcctaat tttctattgg catgtctaaa tttatcaaat ggccactttg
    39121 gtatttttac taccacataa tctaatgttg gctcaaaaca agcataagtt tttttagtta
    39181 ctgcattttc tatctcatcc aaagtataac ctaaagctat cttagctgct acttttgcta
    39241 ttgggtatcc tgtagctttt gatgctaggg ctgatgacct actaactctt gggtttattt
    39301 ctattatcgc atattctaaa ctatgtgggt ttaaagctat ttgaacgtta catccacctt
    39361 gaacctctat tgcatttatt atgtctattg atgcctttct aagtagttga tactcttcat
    39421 cacttagagt ttgacttgga gcaacaacta tactgtctcc cgtatgaact ccaactgggt
    39481 ctacattttc catattacat acagttatac agtttccatt tccatctctc attacttcat
    39541 attctatttc tttccaacct tttatactct tttcaagaag aacttgtcca acaggactta
    39601 gctgtagtcc atgtgaaagt atttctctta attcttcctc agtatcagct atacctccac
    39661 cagttccacc tagcgtatat gctggtctta caactactgg atatcctatc ttattggcaa
    39721 actcaagacc tgcttctaaa tttgtaacta tatcactaac tattactggt tgatttattt
    39781 ctttcattac ttctctaaat aaatctctat cttcgccctt ttttatagat tctatagatg
    39841 ttcctataac ttttacatta tatttatcta atataccagc atcatgtaat tctacagcta
    39901 agtttaatcc tgtctgacca cccatacctg caagtaaact gtctggtctt tctttttcta
    39961 ttattttttc tataaattct attgttaatg gttctatata tattttatct gcaatttctt
    40021 tatcagtcat tatagtagct gggttactat ttactaatac aacttcaatt ccctcttctt
    40081 ttaatgcttg gcaggcctgt gttcctgaat agtcaaactc tgcagcttga cctattatta
    40141 ttggccctga ccctaatact aaagttttct ttatactatc taatttaggc ataactcttt
    40201 ctccttatct aaacaatttt cacagttctt atcttcatca tctatacaat caactttaat
    40261 tactttattt tatcttaagt tcaaatttac tcatcaatac atctatttaa tacatctatg
    40321 ttaattaaac caaacttttt gatttaagtt attcttgttt tttagttagc tattctaatg
    40381 ttatttattt tactaattct aaaaatttat caaaaatata gtcattatct tttggtcctg
    40441 ggcaagcttc aggatggtat tgaacactgt atacatctag cttctcatgt cgcattcctt
    40501 caacagtatt atcatttaaa tttatatgtg tcactttcat ttgttcagga acttctgaaa
    40561 cataataacc atgattttga gaagttataa atacttttcc ttcttccaaa tctttaactg
    40621 gatgatttcc acctctatgc ccaaatttaa gtttagcagt ttttcctcca agagctaaag
    40681 ctaaaagttg atgtcctaag catattccaa ctataggttt tttaccaata agagctttta
    40741 tattttctat aacatcttct aagtcttctg ggtctccagg tccatttgac aagaatatta
    40801 agtcagggtt tatactcaat acatcttctg gagatgttgt agctggaaat attgttatat
    40861 cacatccacg agctataaat gatcttaata tatttctttt tactccaaaa tccataacag
    40921 ccacttttgg accatttcct tttatatgct ctacttcttt tcttgtaaca gttctaactg
    40981 cttctgtatt tgaaaactta tccaatttat gtttaacatc ttctaattta ctgtcttcta
    41041 atgtaattat acctttcatt gttccattat ttctaagtat cttagtcaaa gctcttgtat
    41101 ctattccttc aagtccgata actttatttt gctttaaata ttggtctata tcaatttcac
    41161 atctaaaatt acttggagaa tcacttttct cccttactat gaatcccttt acttgaactt
    41221 tttcagactc tgctgatgat aaatttatac cataatttcc cacaagagga taagtcatag
    41281 taactatttg accatagtaa gaagggtctg ttaaaacttc accatatcct atcatcgaag
    41341 tattaaatac tacttctcct acactttctt ctaaatatcc aaatgccttt cctataaaaa
    41401 ctgttccatc ttctaatatt aaccttgctt tcatactaca gtacctccta taattctctt
    41461 tagacaaact aaagaacatt aactaaatat aagcttttaa atatctatat ctatttttca
    41521 cttttacatt ctagttttat acttatttac atttattttt tatctttttc tattatacta
    41581 caaatttctt aaaaaaaaga agttatctca aaagtaaaaa ctcctagaaa aaataacctc
    41641 ttttttttta tttaataatt aaattcttaa actatacaat caacttaatt tctattcagc
    41701 tatattgtaa acttttaact catctttatt taaatgtttc ttcttaactt ctactaaagc
    41761 ttttagtgta tccagagatg tcattatttc agtagaaaat tcaatagctg ttcttcttat
    41821 cttaaaccca tctcttgtag agtcatttcc tttagttggt gtatttatta ctatatcaac
    41881 ttgtttattt cttatagcat ctaatatgtt tggtctagat tcttctactc tatttactat
    41941 atcagcctct attccatttt ctcttaaact cttcgctgtt ccttctgtag caacaaaagt
    42001 atatcctaat tctttcatat cttttgctat ctctataaac tcatctttat catgattatt
    42061 tacagtagca agtactactc ctctttcatc agacatatgt ctacctgctg ccaagaaccc
    42121 tttatataag gcttcttcta aattttctcc tacacctaga acttctcctg tagacttcat
    42181 ttcaggtcct agacttactt caactttaga taatttagac attgagaata ctggtacttt
    42241 tactgatact aattttggct ctttgtaaac tcctatacca tatcctaaat cctttaattt
    42301 agcccctaac atacacttag tagccaagtc aactattggt actccactta ctttacttat
    42361 atacggaact gttctactag ctctagggtt aacctcaatt atatataatt cattttgaaa
    42421 ttctataaac tgtatattaa ccataccaag cacattaagg tctaaagcta tttttttagt
    42481 gtattctact atcttttctt ttatttcatc agatatattt tgacttggat acattgttgt
    42541 actatctcca gagtgaactc cagctctttc taaatgttcc attataccag gtatcaatat
    42601 atcttcctta tcacatatag catctacttc tatttctcta ccagttagat atttatctat
    42661 aagtactgga tttttatggt ctctatcaaa tgcatcatcc aaatactgaa ttagtttttc
    42721 ttcgttataa gttatttcca taccttgacc accaagtaca taagatggtc taactaatac
    42781 tggataacct aactcattag caacttcaat accttcgtta agtgaccata caccctttcc
    42841 ttttggtcta tttatatcta gtctctctag taaatcatca aatttttctc tatcttctgc
    42901 tgcatctata tcatcaaaat cagttcccaa tataggtata tttttttcat gtaaaaattt
    42961 agccaatttt atagctgttt gtccaccaaa ctgtagtatt acaccttctg gcttttcttt
    43021 ttctattata cttaaaactt cttcttctgt taatggttca aaatacagct tatctgatgt
    43081 atcaaagtct gtacttacag tttcagggtt attgtttatg attatagttt ctatgtccat
    43141 ttttcttaaa gattttacac agtgaactga acaatagtca aattctatac cttgacctat
    43201 tcttattgga ccagaaccta atactatcac ctttttctta tcactaacaa ctacctcatc
    43261 atattgctca taagttgaat aatagtaagg agatatagca tctatctcac ctgcacaagt
    43321 atcaaccatt ttatatgctg gtttgatatt gtatagactt ctcaattcat ataatttttc
    43381 tggacttatc ttcattaagt cagatatacc tttatcagag aatccctttt tctttaattc
    43441 aagaagatag tctttagtta aatcttcaat tttcataact tttaattttt cttcttgctc
    43501 tactatccat ttaaatttat ttataaacca tttatctata cctgtaattt gttctatcat
    43561 ttctacttta tagcctcttc ttatcatttc agctaaatca aatagtctct catcatcagg
    43621 tactacaact cttttcttta attcctcaat gcttctctcc tcagatggtg tgtgaactaa
    43681 tgaatatttt cctgtttcaa gtgatcttat ccctttaaga atagcagcct caaaattact
    43741 tcctatactc ataatttcac cagttgccat catcttagtt cctaattttc tatttgcttt
    43801 tttaaattta tcaaaaggcc attttggtat ttttgccacc acataatcta tagttggttc
    43861 aaaacaagca taagtttttt tagttactgc attttctatc tcatctaaag tataacctaa
    43921 agctattttt gatgaaactt tagctattgg atatcctgta gcttttgatg ctaaagctga
    43981 tgatctacta actcttggat ttatctctat aactgcatat tcaaaactat gtggattaag
    44041 tgcaaattga acgttacaac caccttgaac ttctactgca tttaatatat ctaaagatgc
    44101 ttttttaagc attgcacatt ctttgttact taaagtttga gttggagcaa caactatact
    44161 gtctcctgta tgaactccga ctgggtctat attttccatg ttacatacaa ctatacaatt
    44221 tccctttgaa tctcttatta cctcatattc tatttctttc caacctttta tactcttttc
    44281 aattaatact tgtccaacag gacttaattg tagaccatgt gaaagtattt ctcttaattc
    44341 ttcctcatta tcagctatac ccccaccagt tccacctagt gtgtatgctg gtcttacaac
    44401 tactggataa ccaattgtaa gtgcataatc aagacctgct tgtaaatctg taactatatc
    44461 actaactatt acaggctgat ttatttcttt cattacttct ctaaatatat ctctatcttc
    44521 accttttttg atagattcta ctgaagtacc tattatcttt actccatatt tatctagtat
    44581 gcctttttca taaagttcaa ctgctagatt tagccctgtt tgtccaccca tacctgcaag
    44641 taaactgtct ggtctttctt tttctattat tttttctata aattctattg ttaatggttc
    44701 tatatatatt ttatctgcca cttctttatc agtcattata gtggctggat tactatttat
    44761 taatacaact tcaattcctt cctctttcaa agactggcaa gcttgtgttc ctgaatagtc
    44821 aaactctgca gcttgaccta ttattattgg tcctgaccct aatactaaag ttttctttat
    44881 actatctaat ttaggcataa atttttctcc ttatctaaat ggtttttact atctgtaaat
    44941 aatactaaat ctatattaat gctaagaatt tattaaatat acaatctaaa tcttcttttg
    45001 ttgtgtattc tggaatgtac tgaacactat atattggtaa ttccttatgt ctcattcctt
    45061 ctatagtatt gtcatttaaa tttatgtgag ttacttctgt attttctggc atttctgaaa
    45121 cattatatcc atgattttga gaagttataa atacctttcc agtttctaaa catttaactg
    45181 ggtgattacc tcctctatgt ccaaatacaa gctttgaagt ctttcctcct aatgccaatg
    45241 ctaaaatttg atgtcctaaa cctattcctg tcaatggctt tttgcctatt aattttttta
    45301 tattttcaac tatatcattt atatcctctg gatttcctgg gccattagat aataagatta
    45361 agtcaggatt tatatttaaa atttcttcta ctgtagtcat tgctggtact atagttatat
    45421 cacagttaca agccttaaga gactctagta cactattttt aacaccaaag tctataacta
    45481 caactttagc tccagtacct tttatatttt caatttcttt tcttgtaaca ttttttactg
    45541 aatctttgtt acaatgctct tctaatttag actgaacatc ttgtaatgat acattttcta
    45601 aagttataat tcctctctta gttccattgt ttctaataat tttagttaat gctcttgtat
    45661 ctattccttc aagtcctatt accttatttt gctttagata tgtgtctata tccatttcac
    45721 atctaaaatt atttgggtta tcactttttt ctcttacaat aagtcctttt acttgcacct
    45781 tatttgattc aacatcttct aaatttattc catagtttcc tataagtgga taagtcatag
    45841 taactatttg tccataataa gttgcatctg tcaatagttc tccataccca gccattgaag
    45901 tattaaatac aacttctcca atagcttcct ttagatatcc aaatgctttt ccttcaaata
    45961 ctgttccatc ttctaaaatt aatttcccct tcatataagc tacctcccaa atattttatc
    46021 taagcatttt ctatttctct tacaatatta atagctgatt ctcttggatt ttctgctttt
    46081 gttataggtc ttccaacaac taaataatga gcaccttttt ttattgcatc tgatggagtt
    46141 acaactcttt tttggtctcc aacctctgct gatttaggtc ttattcctgg gcaaactgtt
    46201 ataaaatcag ttccacatgc ttctactatt ttatctactt cttgcgctga acaaacaacc
    46261 ccatctattc ctgattcttt tgccagttta gctctcttta tagctaactc ttctgttgtc
    46321 atattacatc ctatgtcctg taaatcttgg ttgcttaatg aagttaaaac tgttactcca
    46381 actactaatg gcttttctat atttaatctt tctgcttctt ccctagcaat tagtgcacat
    46441 tgtctcattc cttccatatc tgatacatgt attgtcatta accaaacatt atctctcact
    46501 gcagctttca ctgcactttt catagtattt ggtatatcat ggaatttaag gtctaaaaat
    46561 atttttttac ctttttcttt aagataatct attgttttac cttttgtggc aacgtattgc
    46621 tctagcccta ccttaaatat gtctacacta tcttctaatc tgtctattag ttctttagct
    46681 ttatcaaatt cgtcagtatc aattgcaact atcaattttt ctttaccatt tatcattttt
    46741 acatctcctt tttaataaag cctaaataat cataaaaaaa tcctcacacc aaaagaggca
    46801 taaggatttt atctatacat aactctattc attagctatg agatatcttt cccagtctct
    46861 ctggactagt ttaaaagact ttattatatt taaattttta ttttatactc atcaaaaacc
    46921 tctagaagat ttactagagg ttatatacta acattatcta taacccttta gtctctctgg
    46981 actactttaa ggaatttagc tgtaatattt ttctttattt atataacttt atgtatctat
    47041 aggataattt aaagttttat cttttttata attaaaccac taattgcttt ttatgtcaat
    47101 aagtctttga attattcttc atctttatca aacaattttt tctcaaaata tgattctgca
    47161 ttatatattg cagcaactgg attatgccca gttactctat ctttgacaac taaagttgtt
    47221 ataggagctt ccatatattt catggctaaa gtatcgtgac caacacataa tccaagaatt
    47281 acattaaggt caaccttagc ttcatttaaa aataaagctt gtcctattgg attgcacatt
    47341 acctcatctg aacactttga tattgtttga gatgcttcta gtccaattgt actcttaggc
    47401 attgccccat ttttacatat aacagaaaat acttcaaacc catgatgttc aaatattttt
    47461 tgcactgttt gcatttctct ttttagtcca atacaaaatg ctatgccaat ctttttataa
    47521 ccacactttt tagcaaactc tataatctct tttagtctag tatattgaca atacccccct
    47581 gcttcaacta atccagcatt ataagctatt tttctattct cttcttcttc ataaagttgc
    47641 tttgcttttt gttgtagttc aatttctcta gttggacata tcttcattaa tttatccata
    47701 tttccattag aacagcctct aagattacat tttccacact tatacatatc caatatcccc
    47761 ttccaaaatt ttattcatct tgcgattctt ctttttctag agttacattt tcttcttggg
    47821 tttcttcttc tggtttcaca tgctcgacta cagttataaa atatgatttt cctattttat
    47881 tccttatagg aagtttttca tatgaaacat ctattttatt ttttatacaa gctatatcaa
    47941 aatgtcttaa ggctacacct aagctaacct tattcatatc ttcacagtgt ttcttaggtc
    48001 tcttttcaaa taaatgaaga cctcgttcat ccttatggaa ataccacggt tgagaatttt
    48061 ttacagatgg agctcttctt gtcaattcta agatatcttt ccactttcta ttcctattta
    48121 tcttatttat catatctttt actggctttc tatcaggtct agcatatctc gtcctaaaca
    48181 actcttcatt ttttgctgga tatccaaatg ctattattat ataaggattt tctattttgt
    48241 tttcatcatc ttcttctgtt tttattccag ctagataatc taaatcatct tcctcatctt
    48301 cttcaaaatt cttattccca atatctacaa attccaagat atcttctctc tttaagtttc
    48361 cttccaacca gcaagtagct attcccaatg ttgtaaggcg caaaactaca ccttctgtag
    48421 caaatcctat attctgtaaa tagtcctcac ctttgtctga tgtaactact atataatgag
    48481 gtgcctttac tttacattcc ttacccatca aaaaatgtat tatatgacct ctatcaacaa
    48541 catgtgcttt aatatttaaa tcttcattta agtattctaa atttttacaa cttcttttta
    48601 tttcttccat caatggcttt tttatcttct tactggaaaa atttcttaca gattttctat
    48661 aaaaaatggc ttcataaagc tccatttatg ccctcctaac tgaaatcttc tgacgtataa
    48721 actctataaa tttatataaa tactttatat tttttatagt tttatttcct ttttcctcct
    48781 gccctatttt gaaattcata agaatatcta ctctagttta atatagcatt caaaaggctt
    48841 aaattctacc ttatcaatgt ctatacatta gcataatttt tttatttgat tttctatgct
    48901 aatttaaata acaacactag ctattacctt tttaattaag ctttgccaga aaaatttttt
    48961 ttcatttata aatatctatc tcattattat attataagtt tttttcggta ttcttgtata
    49021 gcttttcact aaaaaagtat ttttatttct actttaatat tattatcaac aaaaaacata
    49081 ctgcttaaat aagtttgtta tcctcataat ttgttttaat taaaatattt tttttatttc
    49141 tcaatctata aagtataaat attttgaata tgacccaaaa tctaagtaaa gttataatat
    49201 tttataagtt gttcaatatt aaaaacataa gtaatgttat aatactttat aagttattca
    49261 atattaaaaa tataggagga taaatatgaa tttaaataga aatttagaaa aatacgctga
    49321 attagcaata aaagttggag ttaacataca gccaggtcaa attctactta taaagtcacc
    49381 aatagaatgt gctgattttg caagaaatgc acttaaagaa gcatataaat gtggtgctaa
    49441 aaatgtttat atagagtggt ctgatgaaga aagtactctt attaaatact tatatgctcc
    49501 agatgaagca tttcatgagt tccccaaatg gacagcagaa caatatgtag atatagcaaa
    49561 agaaggtggg gcatttttat cagtctatgc ccaaaatcca gatttattaa aagatgttga
    49621 ccctgaaaga gttgcaaatt ttcagaaggc atctggaaaa gctttaaaag aatggcgttc
    49681 ttacactcta actgataaat gtaaatggag tatagtctct gtgccaacaa aagattgggc
    49741 aaaaaaagtg tttccaaatt tatcagaaga taaagcaata gaaaaactgt gggatgctat
    49801 atttaaatgt tcaagagtag atggtcagga ccctataaaa gcatgggaag aacataatga
    49861 aaatcttaaa tctaaaatgg actttctaaa taaaaataac tttaaaactt taaaatataa
    49921 atcctcaaaa actgatttga ctctagactt gccaaagggt catgtttggc taagtggagc
    49981 atccaaagac cctaatggaa taagttttaa tccgaatatt ccaactgaag agatttttgg
    50041 aatgccacat aagtttaaag taaatggaac tgtttatagt acaaaacctc ttgtttatgg
    50101 tggaaacata attgacaatt tcttcttaac atttaaagat ggtaaaataa tagatttctc
    50161 tgctgaaaag ggactagata cactagaaaa acttattgaa acggatgaag gctctcatta
    50221 tttaggagaa gtcgctcttg ttccatacaa ctcaccaata tccaatacgg atataatttt
    50281 ttataatact ctatatgatg aaaatgcttc ttgccacttt gcaattggtt ctgcttataa
    50341 gacttgtctg gaaggtggaa ataatttaaa agatgaagaa ttggatgaac atggtgtaaa
    50401 tgacagttta acacatgtag attttatgat tggttctgct gatatggata ttattggtga
    50461 gacttatgat ggaaagcaaa tacagatttt taaaaatggt aattgggctt tttaacatat
    50521 gattttaact aaaaagggct gatggaagtt ataccagact tcccagccct ttttaatgtt
    50581 gatgataaat attttttata ttaattaatc tcattattat agattaattc ctattgtttt
    50641 aaacataagt atctaaaact tatatttata ttatatataa aatatcctat ttagtaaaac
    50701 ctttatttta atttatatgc taaaaattta actttgctat ttcaacagca gactttgcat
    50761 cctttgaata ataatcagca cccatttctt cagcgtattc ttctgtcaaa actgcacctc
    50821 ctacaaatac ctttgcattt atctcattat ctctcagtgc ctgaattgta tctttcatac
    50881 tttgaacagt cgtagtcata agtgcactta atcctactaa ttttatattt ctctttttag
    50941 caacttccac tacttcttca atagggacat ctttacctaa atctataact tcatatccat
    51001 aattttctag cattattttt actatatttt tcccaatatc atggatatca ccttttactg
    51061 tagcaactat tatttttcct ttggatacat tattgctact tttacttaat aaagtttcct
    51121 ttattgtatt taatgaaact tttaccgttt ctgctgattg aatcaattgt ggtaaaaata
    51181 tatctccact atcatatctt tttcctactt tatcaagagc aggaattaaa atctcatcta
    51241 atatataatt ttcatccttc tcttttaaaa gattcagtgt tacatttttt gcttcatctt
    51301 ttaatcctct ttcaactaaa atatccaagg gcaaatcttt atcaatcttt gtagatgaat
    51361 ccgatttttt tgaattattt atattgctat attgatttat atagtttata catcctttat
    51421 ctgtgttatt taatatttta aaagaattga tagcttccat catactatat tcatttggat
    51481 ttataattgc taaatcaagc cctgccccta aagctaatgt tagaaaagaa gcattaagtg
    51541 ctttcctatt tggaagacca aatgaaatat ttgaaacacc taatatagtt tttactccta
    51601 gtgtctttac cattgttata gcttttatag tttctattgc ttcttcttgt tgtgctgaaa
    51661 cagttaatga taaacagtct ataaatatat cttttggttt tatcccataa gaaactgctc
    51721 tattaactat cctttttgct atttcaaatc tttcttcagc ctttttaggt atcccctttt
    51781 catcaagtgt aagtccaacc acacatgaac catacttttt aactattggt aatatacttt
    51841 ctaaagactc ctctttgcca tttacagagt ttactattgt tctaccatta taatatctaa
    51901 gtccttgctc taaggcctct acattggaag aatcaacttg taaaggtgta tctactactg
    51961 cttgaatctc tcttattaat tttggcatta gttttttttc atcaatctct ggaagaccaa
    52021 catttactcc aagtatttgt gctccagcat ttacttgttc taaacctaaa tttatagcat
    52081 aatcaacatt ttcatttttt aatgcttctt gtagagattt tctacctgtg ggattcaatc
    52141 tttctccaac aactataggc gattgtactt ccacaaattt tgatggtgaa cagactacac
    52201 atttatcaat tttctcgata catccctttg taacagaatt tatattctca gatatttctt
    52261 ttataaaact tggattcgta ccacaacatc cacctattat agtagcacca acttcaacga
    52321 actttttaac cccttcaaaa aattcttttg catcaacatc atatatagcc tctccatcaa
    52381 ctatatttgg aagacctgca tttgcttgaa ccataacagg gactgtagct cttgatgcta
    52441 ttttttcaac tattggtaaa agttgtttag gtcctaatga acaattaact cctattgcat
    52501 ctacacctag accttctata gtagccacca tacattctgg catacatcca gtaaaacttc
    52561 ttccaccttc atcaaatgtc atagtacaga aaataggtaa atcagagttt tcttttgctg
    52621 ctaatacagc tactttagct tcatataaat ccatcatagt ctctattact attacatcaa
    52681 ctccagattt aacgccttgt agtacttgtc ttttaaatat ttcatatgct ttatcaaaac
    52741 ttaaagtacc cataggctct agcatttctc ctataggacc aatatctaaa gctacatatc
    52801 ttggtttagt attatctaca ttttctatag cttttctagc caccaaaaca gcattgtcaa
    52861 tcacttcttc taccgtatac ttactatcta attttagttc attacatcca aaagtatttg
    52921 taagaattac attcgaacct gcctctaagt atgctgtatg tatttctata agtttatctg
    52981 gattttgaag accaaatact tctggatttt cacctaactt taaccctttt tgttgaagca
    53041 ttgttcccat tgcaccatca aatattaata tattattttt cagatattgt cttatttcca
    53101 caagagttcg ctccttttct atatgtacag tttctatagt ttttacaatt ttcacacgac
    53161 ttttctttct tagatttatt tattcttgta ttagaaatac ctataatagc cactactgac
    53221 tttctcggta tcataattcc attagaagta attgttagac ctatttgttt ttgagcattc
    53281 aaaacgttta atatatctat atttttttct attggtaaat ctccatatcc tgggctatat
    53341 cgcatagtta taaatttatc ttgctttaaa aaaacctttt ctaaattatt ttgaacaatg
    53401 tcacacactt cttctattgc tgttgttcca catgaatcaa ttattagtcc ttttgttaaa
    53461 tttgaataag agtgtcgtct tatttctttt tctatatcta tccctatagt agctgccata
    53521 attacacact cattacattc ttttaaaagt tcatatacat ctttactctc taatgttaaa
    53581 tttgttccct ctaattctac aacattatct ttatttattt taataggata aatcctagat
    53641 aaatatctag gatttatttt atttttagtt atagctacac attcatcaat agtatattta
    53701 aggtctttat ctatctcttg acctctgtat tgtaaatatc ttaaaacttc actttgattt
    53761 atgcttatat cttctcttcc aattaaatta ttccccatat atatttaaag aaaatccttt
    53821 atctaaaaca tcttttgcat attcctttgc cccaaataaa gataagtctc tgtagtttcc
    53881 acattctata gctgtagctg ctggcatttt atctgattca agaacttttt ttaatgcttc
    53941 ttctaaacca atcttaactg ttttggcatc tacatctccc catagtatta aataaaatcc
    54001 tgttctacat cccattggag ataagtctat tacaccatct aatgtatctc ttaaataagt
    54061 agctaaaaga tgctctaaac cgtgcatagc agcagttcca aaactttcta catttggctg
    54121 taaaaatctc aagtcaaatt tagttacttt atctcccttt actccatcaa gtacactaca
    54181 ctttcttaca aaaggagctt ttacttttgt atggtctagc ttaaaacttt ctactttttc
    54241 cattatttaa tcctccatta tactttaaaa tttgttacat taattctaaa aaaaactctt
    54301 cctatctatt attgataaga agagtatatt atttcaagtc atctcatcgt tgttagcagg
    54361 accacctgat aaaaggttgg tataggatca ctgagctaac tctctcccct aactcttgat
    54421 aagtatctta ttaaactgac ttaaattata tattactttt ttatttttgt aaacacttta
    54481 ttgttataat atttatatca cataatcgta cttttatttt ataactaagc tgattgtatt
    54541 attggcagtt gtacttcaaa cacagtttga tatttatcgc ttgaaacagt aatttctcca
    54601 tcatgtaaat ttacaatatt ttttgtaatc gcaagaccca atccagaacc tccaacattt
    54661 ctatttctcg atttttcaac tctataaaat ctatcaaata tatttggtaa atctaacact
    54721 ggaattggtt ccccataatt tatcactttt acaaccgcca tatcttcctt tttctctgtg
    54781 actatatcta cataatgccc atcttttcca tatttcacag cattagttat aagattttca
    54841 aatgctctta ccaatttatt tggatcagct tttacaatta atttttcttc attaaaatta
    54901 attctactaa ccataaattc ttgtttaaaa taaatttcaa attgagatac tacttgactt
    54961 aataactcta ctaaatttat ttctattttg tttaatttta ttgtattatt ttgcatttta
    55021 gtcaattcaa acaaatcatt tataagaaca tttaaatttt tcgatttttc atatgcaata
    55081 tcaacataat acatcatctg aacttcatct ttatacttac cttcttctat cactcctaaa
    55141 taacccatta tggatgtcaa aggtgttctt aagtcatgtg acacatttgt tactaaatct
    55201 gtttttgtct gctgagcttg tctctcttca atagttatat ttctaagttg atggactata
    55261 ttattgattt tatgtgctag ttcatcaata tcatcctttt ctttatcctt taatatatct
    55321 aaatcatact caatatctat acttttttct aagttacctt catccattaa atttacagca
    55381 cttttaatga tttctaattt ttgatttttt ctattagtct ttcttataaa atctacaatt
    55441 tgcttatttc tcttgtacga tataatggaa taaattgcta atgatgtgat tgtaaataaa
    55501 aatggataaa ataaatcata ccctataaga cttctgaaat ctcttgcttg atatacaagt
    55561 tgattaacta cagacatatc actattgaca tataatgatt ttattatata catacttgtt
    55621 aaaataagca ttgaagttaa agcacagctt attataagat ctaatatggg tcgaaacata
    55681 tgatttaata aacttttatt tttcaatttt atatcctact ccccatacag tatgaattat
    55741 tttttctcca tctgtatatt tttcaatttt atcccttatt ctgctcatat gaaccattac
    55801 agtattatta gattggtaat atttctcttt ccataccttt tcaaatattt cttctgtact
    55861 atatactctg cctttattat ttgctagtaa atataatata tcaaattctc ttgatgtcaa
    55921 aattatttca tttccagcca ctgttacact atgtttttcc ttatctataa ttactactcc
    55981 aacctttatg acatctttat cttcattatt agcaccacta aaataatatg ctcttctaat
    56041 cagcgacttc actctcacag taagttcaag tgggttaaat ggttttgtca aatagtcatc
    56101 tgcaccagtc attatccctt gtattttatc catgtcttct gattttgcac ttaacataag
    56161 tattggtata ttcaaacttt ctctaacttt tctacaaact tctatcccat ccattttagg
    56221 catcattata tccaatatca ttaaatgaat attttccttt tttaaaatat ctagagcctc
    56281 ttttccatct tcagctttaa ttacattata tccactattt aaaagatata tctctataag
    56341 gtctcttatt tccttttcat catccacaac aagaactgta ttattcattt ttacacatcc
    56401 taacttaatc tttgtatata gctttattca tataaaatta tactatattt tagttagtgt
    56461 aatctataaa tttattaatt tctaaatttc caatataata caaattattt acacatttat
    56521 attatttatt ttgtaaatat tcttctaaag ttaatccttt tgaataaatt tcctcagcag
    56581 catccttacc aacatatcta atatgccatg gttcatatgc tgtacctgtt atatcttctt
    56641 taccttcagg atatcttatt ataaatccaa acttgtgagc attttctgcc aaccatttag
    56701 cttcttttgt acttccaaca aaccatcttt ctggatttgt taaatcaata caaagtccag
    56761 tttggtgctc actgtaacca ggctttgcta catatgcatc tgccttttct cgcccctgag
    56821 attttaccct tcttgtataa gtatccagtt gagtatcata agatctgtat gctgaagacc
    56881 ctaaaaactg tattccttct gaattagctt gcttaactaa atcttcaact gcctttgcag
    56941 gttctcctgc catttgtttt tcttcctctg ttgcttcttc aacaaaaggt atgtttacct
    57001 tagtaatatt ttcaggagta tagtttttgc taattccatt tgtcttgttt accaataata
    57061 tatttgatat actatttgag tgatttttat tttgagaatt tgcctcaaca tcttgttctg
    57121 aatcatgttg agcagctact attggatctt tatctttctt aagtaatcta tctttagata
    57181 taaatacact tataaatact actaaaataa tggctcctat taatttaaat tttttcataa
    57241 ttaaatcttc tcctttttgt tatgtttgct ataatgttaa ttttagagta taagacttaa
    57301 gtattttata agtaaatctt aaataaatct taaatttaat atttttaaag gatggtgata
    57361 aaatgtctat acaaaaactt ctaagtaaag ctcgtaaggc tatacaagat tttgatatga
    57421 tacaagaaaa tgataaaatt gcggttggac tttctggtgg aaaagatagt ttaactctac
    57481 ttcatatact taaaagttat caaagatttt ctccacaaaa ctttgaattg atagccataa
    57541 cattaaatac tggaggtgtt gataattctc cactagataa attgtgtaaa gaaataaatg
    57601 ttccttttta tgaatttcaa actgacataa aagaaattgt atttgatata agacaagaaa
    57661 agaatccttg tgcattgtgt gctaatttaa gaagaggtgc tttgaacgat aatgctaaaa
    57721 aacttggatg taataaagta gctcttggtc atcataaaga tgatgcaatt gagacatttt
    57781 taatgtctat gttttatgag ggtagagtaa attgtttttc cccaaagaca tacctagaca
    57841 gacaggattt aacagttata agacctatgg tttacataga agagtatatg actaagaaaa
    57901 tttcaaaaga ttctaactat cctattatca caaatccctg ccctgcaaat ggtcatacta
    57961 ggagagagta cataaaaaat cttattgcta ctttaaataa agagatgcct gattttaaaa
    58021 gaaatgtatt tggtgcttta aataattctg agaaattgtt tatatgggat aaagagaaga
    58081 taaaaaattt taaataataa ttaaaatttt taaataaaaa agcaagattg tattaattgt
    58141 aaataatctt tatataatct acacaatctt acttttttat ttattatatg ttattatctt
    58201 taatctatat tttaatagtt cttaatagta tttattttgt ctaatacatt aattataact
    58261 taaatatttt atatattaat ttaatctatt aattcattca atctactggt ttaatccatt
    58321 tttacagtat atacatctac atattataaa aagcaaaatt atattttcta aatattttat
    58381 gttagattat aatattaaat tctattatct ctggtatatt aaaaaatcta aatggtaact
    58441 ttgtacttcc aagacccgaa ctcacatata aatgatttcc atttatatca taaaaccctt
    58501 tagtatattt ccttccatat ggaggagtaa ctaatgctcc cttaataggt aatcttattt
    58561 gaccaccatg actatgccca gatagaacta aattcattgt atctttacta agcatatcta
    58621 ctaaatctgg ttcatgtgct aacaataaat taaaactttt attatctatt tgactctcca
    58681 gatattttat attaggattt ccatttaata tttcatcaac acctaatata ttaatatatt
    58741 tatcatcttt taattttatt tttttatttt catttactaa aagattgaag ttggaatttt
    58801 tcataatctg cctataatac ctaggaagtt tatacatata atcatgattg ccaaatactg
    58861 aaaattttcc caacctagca ttcatacttg ataaaatagt tgtaatttca tctacacttg
    58921 gatttttatt ggagtaatca attaaatcac cagtaaatac tattatatct ggattcaaag
    58981 tgttaatctt attagctact tttttgagat tcttagttga ataaaaacta cctatttgag
    59041 tatctgaaat ttgaactact tttacacttt cagatttact ctcaattgaa tcatttttta
    59101 tcaatgctcc attttcactt atattatatt ttttcacaat taatagactc ggctctatcg
    59161 caactgagta tataaaaatc aaaataaata ttaagataaa aaattttaaa aaatacttaa
    59221 tttttgagtt caaaatatct acctacttat ttattttttt aaactatttg cattacagac
    59281 tcaactttgt tcatttttct gtcatgcatt tttggcttat ttgctgaaaa ccatttatat
    59341 gttgctgtaa gaccttcttt tagtaacacg tttggtatat aaagcccatg ttcaataagc
    59401 ttatttatat caagattaaa gtctatattt ctaaatggga aatacgttct ttctctaaac
    59461 tctacttttt ccatatctac atattttatt ataggttctt tgccaataat ttctccacat
    59521 gtatatataa ggtcatccca agaaattaac tgtggatttg tcacattata ggcctctctt
    59581 acatgaggat ttttcattat gctttccaat acctttacca aatccccaat atatataaat
    59641 tgattactaa cttgttttcc ttttggtact ggtatctttt catttttttc tattttttca
    59701 aagaaataat actctctata taaattatta ttttcaccat atatgtaagt tggtctaata
    59761 attatatatg gtatagggct atttataata aaatcttcag cctctttttt atttaaccca
    59821 tattttcccc agttttcatt ttcacctttc tcattttctt cttttatatt tcttccacta
    59881 tctttatata ctgctcctgc tgacaatact atatactttt ttaagttatc catgcttata
    59941 aaatcaatca gattacttac atcttctttt gtatatgctg tcatatcata tatgtaatca
    60001 tattttcttc ctgtgataat gttttccata tcttttcgaa cttttctatc acaaattaga
    60061 tgttctttaa aaccattata atctatttcc tttttaccat ttgtaagtat atcaatttga
    60121 tacccacatt taatcaagcg cttagcaagt gcagaaccta tgaagtcgct tccacccata
    60181 attaaaatag atttcatttt aagtgcatcc tcctcttttt taaatgactt ccttaactat
    60241 aatatcatat ttttaaatat gcgacaccat tttgtaatat ttttgtctat aaaagatatt
    60301 tataacaaaa tatcttttat agactctaca ttttcgacaa tataagtagg ttcactttca
    60361 ctaatctctt caaaagaacc atacccatac aatactccaa tagaatctat acctattttt
    60421 ttagctccaa ttatgtcata ctttctatct ccaaccataa taactttatc tttatctttt
    60481 acattacata ggtctagtac atattgtata acttcatttt tattcactct tgtaccatca
    60541 agattgctac ctgctatata tttaaaatat ctatctatat caaaatatct aagtatagtt
    60601 tctgcaaaaa ctgttggctt agaagttgct actaataata ttttaccatt tttatagagc
    60661 atttctaata tctctttcat attctcataa attttatttt caaatatccc tttatcagca
    60721 aaatattctc tatacttttc aacagcttct ttagcttttt tatcttcaaa tttataatac
    60781 tccttgaaag tatcatgtaa tggtggtcct ataaattggt ctaagttttc caaatcttct
    60841 tttatgccaa aactatttaa agaatactga atagactttg ttattccttc tttagggtct
    60901 gtaagtgttc catctaaatc gaataatact atttcataat tttttttcat atttcagtcc
    60961 tccatatttg taaaaagtaa tatcttatat attaagttta tctattttaa aaagctatag
    61021 taatagaaat ttctaatact atagcttaag taccaattaa atcttatata tttattttaa
    61081 aaataaattt aaacagctct atttaactgt tatagctgaa actggacatc cttcttcggc
    61141 ttctttacat aaatcttgta aatctgctgg tatttctcct tcaattgcta ctgaatgccc
    61201 ttcatcgctc atactaaaaa cgtctggaca tgttcctata catgctccac aagctacaca
    61261 tacatcctta tcaacaaatg ctttcatact aaaatacctc ccctaaaatt attatttttt
    61321 aattgttgtt tccttagata tttatccaat atataccaat ttaaacatat atttattatt
    61381 ttatcactat tgtttagttt attatagtat tttcgtatcc atgtctataa acttcactgc
    61441 ttttcatcca tgattttaca gtatattgca atcttaattt tttatttaaa acaagttcat
    61501 tattattgta gtcttttata atatcattac actcctccat tgtgaatatt gtaaaatcac
    61561 cttctccacc aatctttatt ctgcctttat ttccatgtaa atcgaaaatc tttgttgggt
    61621 attcagttac tttttctata cacttttcta gggatatccc aagttccata attttattta
    61681 taacatttaa aagagaatag tttacgtctt tcatgttttt tatatgcata tcagtactta
    61741 ttaggtcagg ctctaaacct tgctttattg cttttttaaa aactttaaaa tcaaattggt
    61801 ccactccatg acatacatcg aacaatactc ctctattctt tgcatttatt actgattttc
    61861 ttaatgtgcc agattcttta aggattccat ttgtactatt tccatatact ggtgtaacca
    61921 catctccttt tcccaaaata ttcattactt catctatata tgatggatac tctcctatat
    61981 ataccactaa gggtaaattt aattttttag caacttgctt tgatttctta attatatcta
    62041 taccactttc attagattga aatttactcg cttttacttt tatacccttt atcttttcta
    62101 tatttttttc tacaactgac tcaaccttgt caaaatttat aacatctaaa gaagttgatt
    62161 cattcaatat atttagtccc tcatttgtaa catttaaaaa agaatatact tctgttttac
    62221 actcatccat atactttttt ttaaaatcat agtagtttga aggaccagct gtacctgcat
    62281 caaatataac tgtagaacct ttttcaattc caattgaatc agaatccata cctgtaggta
    62341 attttctctt ataacaatgg gtgtgaacat ctataaatcc tggggaaata tacatattat
    62401 cggcatttat tatctcgaac tctttatttg taagtaattt ttcttttctt attttctctt
    62461 taaggttcaa tccaatagca tatattttcc catgtaaaac caagatatct cttttttcaa
    62521 atttgatacc atctgttgga gatattattg tcccatttct tataagtaaa tttttcattt
    62581 attccacatc ctaattacaa tataatttct ctaatagctt ttcttacata aagaaaataa
    62641 gcctaaaaat aaaaatattt tagacttatt cactatatta tactatatta attatattaa
    62701 attaaataaa atctttaatt tactttaaga agcaattaag tatttgttgc tcggcttctt
    62761 cttcagtaag acctaatgtc atcatcttta gtatttggtc tcctgcaatc tttccaatag
    62821 ctgcttcatg tactaaaaga gcatctggat gatttgcagc aatttcaggt atagcactaa
    62881 tttgagaatt tcccataatt attgaatcac attgaacatg tgcagaacaa agggaatccc
    62941 caataacaca aggattaaac ttttgcttag aattatcttg cccaactgta cgagaaacta
    63001 cttgagcaga agagttttca ccctctaaga taaccttcat attagattct gcaacttgat
    63061 taccatgagt taataatttc tcaaatacaa ctattttagc tcctttacct aggtttgcat
    63121 ccatttctct tttagttgaa tctacaccct taatttgaat tgtttccatt tcacaatatg
    63181 aatcctcatc catattgaca atagtaactg gatttaaaat tctctttcct tctccatcac
    63241 cttcaccata atgtttttct acatatttta ggcgagctcc tttacgtaag aaaaatctat
    63301 gtataccatt atgttcacta tcatcacaac cacagttatg tataccacac ccagcaatta
    63361 taacaacatc tgcattttct ccaatttcaa aatcattata taccatatcc tgtacaccag
    63421 cctctgttac tattactggt atatgtacat tttctccttt tgtatttggc tttactataa
    63481 tatctattcc aggtttatca gttttaggaa ttatagttac attttcagtt gaatgtctct
    63541 ctactccttg cccattttta cgtatattgt atgctcctaa tggagttcca cgaagttcag
    63601 caactttttc taaaagattt aaatctattt tgttcattta atttgccttc ctttctaatt
    63661 aattcatgtc tttcattaat tcacaacttg aattaacttg acacatgatt tcaggtaata
    63721 tagcctcttt tgttccatgg ctttttactg aaccatcttg tagaacaatt atttcatcag
    63781 ctaactctaa tattctttct tggtgagaaa ttatgattat agtctgatta gactcttcat
    63841 gtattttctt aaaactttca ttgagttttc caaagctcca aaggtctatc cctgcttcag
    63901 gttcatcaaa tatagaaacc tttaaatctc tagcaaaaag agttgctatc tcaattcttt
    63961 tcatttcccc tccagaaaga gagttatcaa cttcacgatt taaatagtct tttgaacaca
    64021 atccaacatc tgtaaggtat tggcaacata catcagtaga caatggtttt ccatgagcaa
    64081 gtgtaagtaa attttcaact gtcatacctt ttattcttgg tggttgttga aatgcgtatc
    64141 ctattccttt ttttgctctt tctgtaatac taagatttgt tatatcttct ccatctaaaa
    64201 ttatctgacc actcgtagct ttttcaattc ccataataag cttagcaatt gtagattttc
    64261 ctccaccatt tggacctgtg ataacaataa gttttcccct ctcaaatgaa aggctaacat
    64321 catttattat tcctagttcc tcattgttag actcaacatt aaaggaaaga ttttttattt
    64381 caagcataat acccctcttt tctataaaat attacattaa tatccattct tttattatat
    64441 cagtaatttt tatatatcag caactctaag gagataaaat gtatattaaa taataaaaca
    64501 aagttattga aaagtaaaaa agatgagttt tatgtaaact catctcagaa atttagtata
    64561 tcaacttata tgtatttaaa atttaacctt ctatatactc taatattatt ttttgattat
    64621 cttttaacat aatttcttct tttttagatt ctattccatt cttttttatc tttacctcag
    64681 ctacaaaggc atcattacct tcaaccattt ctaatagttc atacgctttt ttacgaccta
    64741 ttttagttgc tatatctttt agtactgcca ttttcttaaa cattttatca cctctactca
    64801 aaatttacac ttaattttta attatataat tctaatccta gactagttta taataattat
    64861 tgtctctaat tatatcagat attgagtaaa tttaatactt tgtaaaatta tttatcctct
    64921 ctgaccaaat aatcatttcc atcttggtct ttaaaagaaa acatccttcc atatggcatc
    64981 tccattaatt ccccaacctc aacctcgtta tttgccattt gttcataagt tccattaata
    65041 tctcttgtac ttaaaattat tgatggatga gatacattta tctctttgtt ttgcttcatc
    65101 attagatttt tatcatacaa cacaaatgtt gtaaattcat ttttacttgg tgctacttcc
    65161 acccatttca tatttggacc catttccttt tcataagtta ctacaaagtt caatttttct
    65221 gtccaaaata actttgcatc ctcttgatta tttacataga gagttatttt tcctatttta
    65281 tttatcataa caatacccac ctttattatt aaataaatac ctaatatttt ttatatttaa
    65341 taatataccc atatatatta ttttctatag atatatattt ctaatattta tcgccaaatt
    65401 atgtaattct gctcaatata taatttataa tatccatact attatagcct ttatttatgt
    65461 aatttaatca ccttatatat catacttata attatgataa taactacata aaaaatcact
    65521 tctaaataga gttatccatc taaaagtgat ttcatatatt ctatgcaact ttgtgtttta
    65581 gccactttgt tcctcttaat cttaaacaat ataaagtccc tctaacaagc caatcagtat
    65641 acatacctat ccaaattcct aacactccaa attctaatac aacccccaat acgtaacctg
    65701 taaaaattct aaaaatccac atacctatta ctgcagtcat cattgtatat ctagtatcac
    65761 cggctccctt tagccctgct gataatacaa aggatatagg ccatattacc atagctaaac
    65821 aatcacttcg aattaattgt gttgagatgt caattacact agcattttga gtatacatac
    65881 ttgaaatcca gggtgcaatt ggtataaata tagctcctac tataaataaa caaattgttg
    65941 caaatttagt taaatataat aaagtactct tagctccttt aatatctcca cgtcctatat
    66001 actgtcccac caaggttgta gcagacaaag ctaaagcatt cccaattaca tttattatgg
    66061 atgcaattga cattcctatt gcattggatg caattgctga tgttcccata gtaactataa
    66121 atacttgaac aatcaattta cctgcattaa aaagtagttg ttcaactcca gctggtattc
    66181 ctatattaaa tatagacttt tgagtttcaa catcaatctt aaatggaaat attttaccca
    66241 tagatataaa ttcgtttcct ttaaataaag ctcttataat tactatacat ccaattattc
    66301 tagctatagc aatagatata gctgcacctg ttatgccata ggatggtgtt tgcaaattta
    66361 ttcctagagg atttaaatca ataccatata taagtatata tcctaatgtt acatttacta
    66421 tattcataaa catagtcaca tacataggtt tctttacatc tccacaccct cttaaaatac
    66481 catttgctat ttgttgtgtc gcaataaatg gatacgtaaa taatgtaaac tctatgtata
    66541 attttgcatt tgattttacc aattcttctg cggaaccata aaataaatta attacaccag
    66601 ttctaaaaac ccacatcaat attgttattg taaaggataa tattactcca gacactagag
    66661 cctgcttaat agtttcattc accttttcac tatctttttt tcctatttgt tgagctacaa
    66721 caacagtagc tccaacagat agtgcagcaa atacagatat aaatatatta tttattgaat
    66781 caaccattcc aactgcagat acagcttctt ccccaatatg acctgccatc attgtattaa
    66841 atactcctaa aagcatgaca aacgtctgct ctatcattat aggaattgct aactttataa
    66901 catttttcct tataaacatc cctattcctc ttttccctct ttatataaat ttaattttta
    66961 attagtttat cgaactgtaa attgacaatg caaagtttag aattgtattg ttcgcattat
    67021 aatatactgc tttcaaataa tataaatctt gtttaatatc atttgaacac agtatatctt
    67081 tataattatc ttatgtttat tattttttat ggataccaca tttaaaatat ttattaattt
    67141 aatataaata ttttccgtta ttattaaaag tagctatatt tcgttaatat tgtatcacta
    67201 tcgtgtagca ataacaataa gtacatttta tatatttttt ataatattat ttaatcatcc
    67261 aaacttttac cactttttca atatataaaa tattacactt tagatgtaac aaaatcgcat
    67321 ccatttaaat attgtatttt atagactaat tttaggatgt gatactttgg ttaatttaaa
    67381 tgcaaataat ctaaatgtaa atatggttta tcctatttct tccacagcac ccatacgttt
    67441 cagaagatat actgtttcat atttagaaaa catggaaaat atttatttaa ctatagcaac
    67501 atactttgat acacttggtt taggcacaat gaatatcgac aaagtttatg gtcaatgggc
    67561 ttggtttact gataatatat atgatttaaa tctatttgtt tttgtaggaa attatcctta
    67621 tcaaattgct aaaaacagat atgatacatt tgtagatatt ttgccagtag ctattacttc
    67681 tattgtcaat ggagatagag tatttttaat ttcaaatcct tgtttgttaa attcaaaaat
    67741 tacagttaga tttatatcta gtcatcctac tcttaataga acagttgatt atggcaatat
    67801 tagagatttt attttttaaa actgcaacat gatgtgctat taaaaaatac cctaaattta
    67861 atgatattat taaataacta gaatattttt aattggcaca tcatgcctag ctattataaa
    67921 ttcataatat tattttactt aagataagta ctgtatttta tctacttgta tatttttatt
    67981 tacctagttt ctcagttcta tatcctattt ctttattagc tagcttataa ccttcttgta
    68041 tcatttcttc tctcgttaat gcactcccta ataaattgtc aatactcagt tgctttctat
    68101 cactaaaata cttatccaat aatgattcct ctatatcttc ctgatatgcc aaatttcctt
    68161 catgcattat atattttaca tcaaaacctt ctttatttaa tacttttccc accaagatac
    68221 ttctatgaca tcttataggt tcttgcatag ctcctaataa aactatccta taacccattt
    68281 gacaaccctt ttttaatctt tctattccgt ttaaaaaaat atcttctttt gctactttct
    68341 caaaatctgc ataaccttct tgcgtatata catctttatt agttctttta gctccaaatt
    68401 cttttcccat gtatatatat aaaaatccgg aatttctaag agattcgtta aatgcctctt
    68461 tattgtattg aatattatat ttagaatatg gagtttctct aatgtcaact acacaattta
    68521 tgtcatattt ttttatcata ttaataagct tatcatatgg ataatttgaa tgtcctattg
    68581 cgaatatttc catataaaca ccctcctatt ctttgaaatt agtatctata tatgtagata
    68641 cccgatttac ttaaaattaa ataaagtatt actttaaata cccaatatct ttttttcttg
    68701 atattgtata tttttttact ttatatcctt aaaaaaatat acaactttat atataaaaca
    68761 tcaatattta tatatatttt gtatattaaa tacaattatt tataaagtct ttaataaaaa
    68821 tttataaata gagcatcttt agaaaactat tataataaaa aaataagagg ctgtctaaaa
    68881 atatagataa gccttttttc ataatcgtaa ttataaaaat atacttgatt tcatatgaaa
    68941 aagagtgtct cataaactaa aatgtttact ttgagacacc acctttttta ttcttattta
    69001 tactttgtag acatattata acatgcgttt cactggtatc tgaacttctg tcaaccagtc
    69061 ttcttcactc tctttattcc atataccatc tatataagat tctctaggat ttccaaccac
    69121 tttatattta ttgtcctcta tccatttaaa tgcatctgcg taagtttttc ctaatgttga
    69181 atatggacca ttgtgtaata tacaaactgc attttcaact gcatctaatt ctttaaattt
    69241 taatatatcc gtatcttcct ttaaatcatt tatagcttga cacatttcaa catccatatc
    69301 agtctctcta tattcaccat catgatatat attaaaacaa taatcaggaa ctgcacatgt
    69361 acaccctgtt ttcatcattt cttcagccat tacatttgga aatagattaa aaagttcatc
    69421 ataccccttt aacacttttc tcatagaagc aactttaact tttggtaaag acttaataat
    69481 tacatcattc atattgactt ctcctttcaa attcataagg taattacgta gtttaattat
    69541 tttatattct tcacttttaa ttacatccaa catttctttt tctttattca ttaaaatatt
    69601 ttcaacttct tcaggatttt ctacagcttt ttttatctca tctaatgata aacccatttg
    69661 ttttaaagtt attatctgat gtaatttagg taattgctct gttgtataat acctatattt
    69721 tgtaaattca tctacatatt ctggttttaa caaccctata tcttcataat accttaatgt
    69781 ctttgtagtt attttattta ttttagaaaa cattcctata gaaaacatct catcacctgc
    69841 gcattagact tgattaattt aagtttaaac tttcccctta ggttaaagtc aatacaaaat
    69901 aaattataat tgtattaatt cttcaattct atctccactc aataccaaaa tatcccctgt
    69961 ttttataatg gttgaacctt taggtattaa aacctgttcc tttcttttta tcataactat
    70021 taatatatcg tctggtatat tagaatctat tatactttta ttagcccatt tattaccctc
    70081 atcaacattt acttcgataa gtttagagct aatttctcca tcataatcat taaatgtttt
    70141 taatacaggt gtattatcat caactaaatc caactttctg gctacagttg gtatcaatga
    70201 accttgtatt cctactgaaa gcaacgctat aaaaaatatt atatggaata tgtcattctc
    70261 tatggctact ccttgagtaa cagcataaat tgcaaaaact actgaagccg cacctctaag
    70321 acctacccac gatatgaata atttttcttt atttgagaat ttaaattttg ctagaactat
    70381 aaatgttgct aatggtcttg caataactat catgaatata gatatggcca ttgctatacc
    70441 aaatacattt ggtaacttag aagggaaaga taacaatcct aacataaaga ataacattat
    70501 ttgcataatc catgaaattc catcaaagaa atgaaccaaa ctttttttaa gaggtatcct
    70561 actatttcct ataataatac ctgaaatgta aacacttaaa tatccatttc ctccaagata
    70621 ctcgctaaat gcataagaaa gtattgcaat agctgttata aatatagtat aaaatccttc
    70681 tatctcgaag tttgaatgtc ttaaaatata aacagataat tttgctagta taaatcctat
    70741 agctaaccca aaagctattt gttttattac cattggtgca ataagttcta ccccagaatt
    70801 attcatcaat gtcaaaagaa ttagtgtcaa catatacgct attgggtcat tacttccact
    70861 ttcaacttct aataatgatg caagtgaacc ctttaagttt agtttttgag aacgcaacac
    70921 agcaaacaca gatgcagcat ctgttgaagc tgcaattgcc ccaattaata aaccttcaag
    70981 taaactagtt cctattacca tgtggcaaaa catacctgta accccagccg taattattac
    71041 acccagtgaa gacattaata tagaaggtat agcaacaggt ttagccatat tccagtttgt
    71101 tccaaaccct ccaaaaaaca ttataaatat tagtccaata gaacataatt gttttgttag
    71161 ttcatagtta tcaaaataga ttcctaccat cccatcagac ccaaataaca tccctagtaa
    71221 gataaaaatc aataatattg gtactccaaa tttatacaat accttgctag aagttataca
    71281 aatcaatagt actaacccac ttataatcat taattctgtc atagcatcaa ctccatttca
    71341 tataaatttt gtagattaat ttacatctac aattttatta cttattcaaa tataacatga
    71401 cataaatttt ataagttatg gtacataaag ttcaacaaaa atttcacaat gcattaaaat
    71461 gtgagtgtta tacttaaatt tatatatttg ttttaattat attcatttaa tatttataat
    71521 ttgaattttt ttttattaac atttcatttt tcagttgatt gtttaatata tttcattttt
    71581 tatagtaatt ttatatataa ctacgaaata taaagtaatt agataagtaa caagaaacta
    71641 acatgtaatg ttagctactc tagatatgaa atcttaaaac ttttaaatat tgaaatattt
    71701 ctttatatat attattgtat atttcttata aattattgtc aatttatttt ttcttaaaaa
    71761 taaaataatt gcataattta tttcaaatta tgcaatttat aaaatttatt cccaaaactc
    71821 ttttactgct tcgattatct cactataagg caataaagtc gcttcgatta ttgatttatt
    71881 tgtcttttct aaataatact taatcatata atatccacaa gcatatcctg cacaataagg
    71941 caaccctact ggaaaatatc cttgcatttt agctatatca tcaccataaa gataagatgt
    72001 tatattttga aatccagttt cttttaaagc actttttatt attggcttta tataagtatt
    72061 taatgtttcg atatctgttc tactgaccca aggtcctaac atttcctctc caaacatcca
    72121 tgttgcaaaa ttttctgcaa gaccttcatt tatcatcatt tcttctaatg ttatattatt
    72181 attccactct ataaactgaa atctaatatt gtgattacat tcatgtgcta ttaatactgg
    72241 taatctattg atagtatatt cattaggaac caatgataga aatatatatc caggaatccc
    72301 accatcaccc cagtatccat cacttaatat tgtataagga ctatttggat tcgccaataa
    72361 tattgaatat ttatagtcct taatgtttaa atcataccct tcttttataa aagcatttat
    72421 agagttttct atggtttctt tacaagtggc ccaaatttta tcagcagata acacatttat
    72481 attctttttt tgcttttcat caatatcctt aggcgataaa acccctaaca tttcacttgc
    72541 tataattaca tcatatccac ctttctgtct agcaactatt ggaacattca tacacttcca
    72601 cttaaattca aaaggcttca tcaattcata tctgtatata tcttcttttt tgtttattgg
    72661 tgcatccatt atcttcttgt atattttatc tgagcgaatt tctataatat tcatatttac
    72721 catctccttt aagacaaagt atatacaatt acgtagcgtc aatgtcaata tacatttttt
    72781 ataatgtcac cttaatcttt ttattatatt ttatcctgta aaccttccgt acatataaca
    72841 tttttttaaa ttaataaatt tgtataatat aataataaaa aattatatac ttcaaggttt
    72901 ccctatgata caatttacta aatcataatt tagattatca ggtgcaacta taaattattc
    72961 tatatcaagg aggatatatt ggtcatgcta actccatatt taatatttaa tggtgattgt
    73021 gaaaaagcat ttaattttta tgctgaggct ttcggaggag gaaaaactat atttgcgcga
    73081 ttagacagca atccaaacaa tcctgttatg cacgcaagtg ttactttcac aaaatacgaa
    73141 ggttgtataa tgggtgcgga tacagacaag cctgttgtaa tttctggcat ggcgatttgt
    73201 gttgttctac catctcgaga agcgatagaa gaaatatctg taaaacttgc cgaaggtggt
    73261 acacttgtac aagaattttt accacaccca ccaccacatc aaaatgatgg tgctgctgaa
    73321 gtacttgata ggtacgggta tacttggtat ttaagtacat agttaaaata aaaaaactac
    73381 gtctaataat cataatatag aacagataaa tttcaattta atagtgtagt aaaaaagccg
    73441 tgtcctaaga ctgtcacggc ttttatttgt ataaaaattt aagtaaacat ttttgctaat
    73501 acgtgagaag tataacttta aattaatttc atatgtagta ttggaaatgg gttaccttgt
    73561 ccatctattt cagacctatc aaacacttta aatcctaagt gaatataaaa tcctacagct
    73621 tttttattct gctcatttac atcaacatat tttacattgt atttatctat agcatatttt
    73681 attaattttt taccaatacc atttcctcta tatttatctt ctataaagag catctcaatt
    73741 ttatctttat ctattcctat aaagcccttt attatatcat tatcttttat acaaactata
    73801 ttttctactt ctttaagtcc aatttcaact aatggtatca aagattcaat atctttttct
    73861 gttaaaaaat catgagttgc tcttactgac gattcccaga cttgcaacat ttcgtcatat
    73921 tctgttgaat ttatttgttt catttcaaga attattccag atttcataaa aatttccttt
    73981 ctatatcact tttaattgta taacacttct ttatacaaaa cttagaaagg actacgaagg
    74041 ttaaatatca tagtcctcat taagtttaaa tattatctat tatatatttt taacatttat
    74101 atactataat ctagcaaatt tactacaata attcatatta gtttatacta aaggagcttc
    74161 tatttgagta gtaaaaagga atttatgaca gtgaccatca ttaacagtag tttctccgca
    74221 tactaagtga atgtgtttat cagttccagg tattctaatt gctggtcctg ttgtaacaca
    74281 tatcttatga aaatggtcaa ggaaatctac attatcattt attttatgaa catgatttgt
    74341 acctccattt attggtataa cttcaccagt aacccctgct gcacggtggt tatgtctatc
    74401 ctcacattct tctgctaact taacactttc tgaatattca tgaacatgtg tcatttcctc
    74461 ataatcatta tagcacttgt tgcacttatt gtatttataa tcatcataca cataatctct
    74521 ttcacattta taattttgat aactcatttt tatatctctc cctatattat attaagaaat
    74581 tcttgtaaag aatctctaat gtataatatg aattaaagtc aaaaaagttc atattttgta
    74641 aaattatgta ttaatttaat tatttttccc agtatttagg gcgtattagt gaagctggta
    74701 acttcgtact agaatctcct tttgcagtat ttacttgtaa ttgtgttaaa aatatactat
    74761 tttcaagatt agcacctcta atatcacaat ctcttaagtc tgctcctatt aaatttgccc
    74821 cactcaaatc tgtatttctt aaatttgctg ctattagaaa tctacctctt aaatctgctc
    74881 ctattagatt tatttttcta aggtctgctc ctattaaatc tatattttta cttaattttt
    74941 tcatgttttt aagagtagaa gtcttgataa atgatttaac ctttcccatc acagactcac
    75001 tcgcttgtga taataataaa ttaacctttg ttctatgtga tatgatatcc aaattaatta
    75061 tctgttctgg gcccatatta gttatctttt cagtttcttc aattattaaa tcaatttttg
    75121 atttgattgt atctgatata tttaatacag atgcttcttt aagataccat aacatttcat
    75181 gtaattgtct cataattaaa aacacttcag acatttgatt tgttagttct ggtgattgca
    75241 tccagtctat ccccttatat gttacttgtg ctactttttg acctgaacca aaacaatcat
    75301 atgcagtaca ccctttaaaa cctcgcttca taagactatt atgtacagaa catttaaaat
    75361 ctggttgtaa attaatacaa ggttttcctg attccttatc gataggaaat ccatctgaag
    75421 cagaaaaata aagagctaca cagcaaagtc caaagcactt cttacagtca atctttagct
    75481 cctcaaataa cttattatca tatatatttt tatgtatatc tatcatattt tttctcctct
    75541 taaactttat ttttaatatt atattatcta taactaaatg ataatcaagt cccttattta
    75601 acagttctta ttcttaatta taatttaagg tattatttat tccaatagca tacataagtt
    75661 tctttatact tgtaacaata cctttatact aagacttatt ttaaatgtag cactgtaata
    75721 ataaattgtt tatatactca taatgtattt gataaattgt aaatctttat agaagttgaa
    75781 atttttaatg attttagaat aaagatataa taataaatac aatttataaa atcagaaata
    75841 tataaattaa ctatacaaac ctaaataaca tagtatttaa atttacaatt tcagtataaa
    75901 tagtacaaag tatattaatt taaataagat tggcttattt gtagaggaga gaatattttg
    75961 gtgttcaata aaatttatat ttaataaaac cataagaaaa tataaagata aataaacaaa
    76021 cttttattac ttaatagatt cttatggttt tatactgtac tgaaaaacaa taaacactac
    76081 agcttattta taatattacg cttttttaac aacagaagac tttagcttca tagctccaaa
    76141 accatctatc ttacattcta tatcatgtcc atctgatgag tcatggatta aacggatatt
    76201 tttcactttt gttccaatct ttatagatga tgaacttcct tttactttaa ggtctctaat
    76261 tactgtaaca gaatctccat catttaatac atttccattt acatctttga taatatttga
    76321 atcttcttct gctcccaatc ctaatgccca ctcatgagag cattctggac aaactaaaag
    76381 agttccatct tcataagtat attctgaatt acatttcggg caatttggta aattttccat
    76441 ctttatatgt cctccatttg ttatttttag atttcttatt atataaaatt tcttttgagc
    76501 ctttatgata tcatattata cttatattta caaactacta atttacttaa tgtttaaatt
    76561 ctattcgtat tattattaaa cttgatttag ctgtaatctc tttcttatat ttattatagt
    76621 ttatattatt acaattttat aaccctatct gcctgctccg ataactctaa atcatgagtt
    76681 acaaatacga tagttttacc attcttattt aggcttttaa gtatatcaaa tactatgtct
    76741 ctattttttt tatctaaatt acctgtaggt tcatctgcaa atattacttc acattctttt
    76801 aatattactc ttgctaatgc taccctttgt tgttctcctc cactcaattc gtatatcttt
    76861 tttttattgt attttctaag acctacagac tcaagtgcgt aatttatttt ttcattatgg
    76921 ttgatatttt tttgatactt taaagcaatt ttcaagttat tttcaacatt ttcattctca
    76981 attaaagcat aattttgaaa tagatagcca taaaaatccc tttgtaaaat tcttatctgt
    77041 ttactatttg gattttttat attatttatt ataatatcac cagaattagg tttttctaat
    77101 aatcccatta tattaagtaa agttgtctta cctgaaccac tatttcctgt tatcgctaca
    77161 aactcgccct tagaaatttc taggttaaat ttgtctatta tagatttatc tttaaatttt
    77221 ttagatatat ttattaatga aatcatcttt ttaatgttct ccttttataa ttttattaaa
    77281 tgaactattt gagataatct tgtctaatac aatagataca attacttcta taactaatat
    77341 cagaagtcca aataagataa tattattact taaatctact cttgttgata taatgcctat
    77401 tggaataatg tttgttaata ttaatgagac tattaacaac atacttctag ctgtagttga
    77461 ataaccaaat atttttttaa tatataactt atatttattt ctttcatagt agctagctac
    77521 tatattgtag gtaatcatta agtttgatat tgctattatt attatagtaa aaatttcact
    77581 attcaaatat ttttctagtt tatttatttc taaaccatac tcattataaa cagcatgtaa
    77641 actttggata tgcgcttcta caccttgagc ttcaataatg ttacttatat ctgcaagggc
    77701 atctaatttc ttagaattaa aatatacaca tctagatata taagaaagat aaaaagaatc
    77761 atcaatatta tctatgtcaa ctattgctat tgggtcatca atgagattcc tattgtcatc
    77821 cataacaagg gagttataag taaaatagct ttgattatta tctacatata ttatattaac
    77881 atttaaatct gacttctttg ttttatttaa ctctctattt aactctttat tgtacatatt
    77941 ttctacttct attttttcaa aataaaataa ttctctaaac tcttttttaa tctcattttc
    78001 atgtacttgt aactttttag gaactaataa atttatagtc ttatcgtcat aatcgattag
    78061 attaaatatt tctttgccat ttgagtaaat agggttaact ttaagatagt ttttatttat
    78121 ttttatattt ttaccatatt gacttacttc tgggttttta ccctttgaat ttatttcata
    78181 catgtaactt ccatcttcaa gtttttcaaa attagttgaa tctattaaga aagcatcttt
    78241 ttcttctacc aaatttttat agaaaccttt aatcttggca tttttaatta cttcttcctt
    78301 tcctaaagat tgttcgcctg tatctttaag agtaagatta taaacatttt ttgctttatc
    78361 ccactcagat agatttccta actgagtttg tagcatatta taatttaaaa tacagttatt
    78421 tatggataat ataagaaatg atacaaatac aattttcaat gtgaaatgca ttatatttac
    78481 aaaaccataa gatttttttc catttagaga tagcacatat ttagaacttc tactattaaa
    78541 accaactatt aatatagata tcaaaatatt tatcaaaata catataatcg aaaacatagc
    78601 aaagtataag catgctctaa cacctatatt taattttaaa atatagatta tatatattaa
    78661 taatgctgtg acagatgata aaatcataat tctaagtata ttttttataa ctctagcaat
    78721 tatatctagc ttagagtatc catttaatct taaaatagaa gcctctctac tcacactaat
    78781 tgaataatgt attattgtag ccaagaaaca aaggataatt agtattaaat ctctaattat
    78841 tgaaggattt aagtataaat ttgagttaac atatctatca tgtaatcttg ctacaaaaat
    78901 acttctgtct acatttagtt ctcttaatat tttatttatt gtatcttcat tttgagttga
    78961 aatatataag attcctgatt ctccaacttc acttatttta ccaaaatccc taattaaaat
    79021 tgatatgtct ttactcatag ttgagaattt acctacttga ttactattat tagtgtttat
    79081 attactaata aattcatttg aattagtatt aggaaatttt cctgatttta actttatatt
    79141 gttattcaaa cttgtatcag tcgtatatat agataatttt tcattattat taaaaacata
    79201 ctttgatata gccacattat tttcatctgc aatatcttta atccacttac tataattttt
    79261 atttaacttt ttataatctt taaacattac agatatactt gttgtatcgt tatataaaat
    79321 attattaatt tcattatctt taactatatt tagacctaat aaagatacta ttaatagttc
    79381 aattgtaaat aatacatata ttatcttttt caattatagc tccctcctaa ttgtttttat
    79441 tctaaaagca aaatacattt tactttagtt aaagtataat gctttgtgcc ttttctaaac
    79501 aactactata ttgtcacatt ctaaatggca agtgtctatt tcgtcacaaa gataaaaata
    79561 gccttaaagc agttaatttt ttataatcaa ctgttttaag gctatttttt atttttagca
    79621 aacaatattt taatagtggt ataaaattag tataattcat taatatagat tctagtcttt
    79681 tcagtaagca actaaaataa tatcttattt aaaacgaaat ttaatttaag tccaatataa
    79741 actttacttt accattaaat cgtgctagta cataggtatg cttctttttt attccatata
    79801 atggatatct tatgaatatc tatagaatca agataataag gttgtccaat ttggaattta
    79861 gaatatgtat ttttaaattt tttatttaca tataataaaa aattattttc tttattaatc
    79921 acacaaatac actggtcaat attatctaaa atattctggt attgttgaat ctgttgatta
    79981 agtttattat tttttttacg ttgtaaaaac attgatataa tttgagaaat caatgataat
    80041 gtacttattt cctcttgtga ccatagacgt agtcctgtgc attcatcaaa tccaacaaat
    80101 ccactgaaaa ctctatcttc tttatatgca cattgaagtg tagagtggat accttgacta
    80161 gaaaacaatt cttctagttt aggacttaat gtatggatat ctcgacaata aaaaactaat
    80221 tcatcctcaa aaagcttttc ataatcctca tagtcttgat aattgctgtt ttgcaaataa
    80281 gccatttgag aagagattcc ttcattacac cattcataag tattagaagt atatctacca
    80341 tcttctgtat tttcaaaaat ataaacacga cttacatcaa actgtttccc aacaacctca
    80401 agtatcatat taatcgcctg gtctatatca tcagtctgat aaagcatacg gaatatataa
    80461 cgtgtaagat tatcaggata ttcagcgtat tgtttttctg aatcaataac tgtaccaaga
    80521 gaagaacaat caaattcttc taattcttta aaataatctt ggttgtagat tacataatta
    80581 ttttttccca tattttttgc ttgatacagg gctttatcag ctcttgcata tatttccttg
    80641 aatgtagtac catcctttgg atatatagct attcctatgc tacaagttac ttttagaaaa
    80701 cttttttctt tctgaaatag atgacggaac atatacaata gttcttctgc tttcttttct
    80761 gcatctttaa ctgaggaaat attcttcata aaaattgtaa actcatctcc acctattctt
    80821 ccaacaacat cactgtcacg cattattttt ttcatacctg atgccatctc agtaagtact
    80881 atatctccaa tcatatgccc ttctgtatca ttaatctgtt taaaattatc tgtatcaatc
    80941 ataaacagtg cacccataac atttaaattt ttttcaaaat atttcttaat ctgcctttca
    81001 gtctcagcac gattataaat tcctgttaat gcatctttct ctgatatatg ctgtaatttc
    81061 tcaatctgtt ttctttcctt tgttatgtca atacctatac tataaaaaga tggtattcca
    81121 tcccaactgt cttccccact gatataacac aatgtaacag tccatatacg ttcttccctt
    81181 gaacgtgtat atatttttgc ttcaaataca acattatccc cagactcctt caaatcttgt
    81241 gccagtttct tactacgttt ataatcttca gaaaataaat atccacattg attattaagt
    81301 tcctctgcaa actgttcctt tgtatattca atcatattca aaaatatatc attacaccaa
    81361 agtatagtaa gataatctct tgcatctaat ctaaccattc ctgctggaat agttttcaaa
    81421 attgattctc tttcctgatc tttttttgct aatttatatt cagcactata catatcataa
    81481 gataattcaa tacgaactct tcgcccttgc caattcaaca tacggtcttt aattataaat
    81541 gttcgtttca gttttttatt ataaaattcc cattcatata tgtcatcttt ttttaaatac
    81601 gaatttgtac aaaacggaca tggcgaagtt ctaccttgaa ttacctcata acattttctt
    81661 ccaataagtt catttgctga tgcctgtaaa gtattgcatg agtgcttatt taagtatagt
    81721 aattcatatg tatccatatc gctaatataa acattcccag catactctga catcatccat
    81781 ttaaaattct ctgtactctc tttttccata tcagatagtt cttcttgctt tatttttaac
    81841 tcattaattt ttgaatacaa tatatagacc attgatttct cattatcttg tgattcaatt
    81901 aatataccag tcattattac ccaaacaggg tctccattat ttgctgaaat gcaaatttga
    81961 tattctatac tcttttcgcc atgatgataa gcctctaaaa aatgattttt catagattca
    82021 aaatgataaa gattctgttc ataataatct tttaaactag aaaatttaac taaaaattct
    82081 tcttctgtat atcctaataa ttgatagaat gatgtatttc cccatattat tgtaaatgaa
    82141 tcatctaaaa aatgtttact gaccccaata ctcatagatt ttagaatatc ctctgatata
    82201 acttcattct ttgttgcttg ttctttttta cacattcgat gtaacctaat gtcttctttc
    82261 attgttttaa ttatcctcct atctttagac tcacttttaa ttcactctgc tttttaatat
    82321 aatgataaaa gtgaatcttc aacgtgtata aattgatttc atttacaatt attttttgtt
    82381 tgaaattgaa ttttcacaca cacttgctaa gattctccct ctaaaacttt taatttagta
    82441 atttttttga tgccctattc accatttaat atcttaatta tcgattcttg ttcacttaaa
    82501 tctgtattta acttttcccc taaaaacaca ttattttctc atatttacta aaaatcgcct
    82561 tcttttaatg aaattatatc ataacttaag ttttaaatca tttttttcca gatagaaaaa
    82621 ttaagataaa attactgaaa ttatatgtaa tataatagaa atgtaaactg ttttaaattt
    82681 gaataatatt aaaaaggctg tatcatagta attataagat actatgatac agccctatgt
    82741 taaatttttc ttatattttt aatgatttca cgaatctttt tagcattttt agcaatatct
    82801 tcaacagaac ctttagttaa taaaccacca aatccacata catcaactcc attttctaac
    82861 catatatgta ggttttcaat attaatccct ccacttgcta aaactggcat atcaggtatt
    82921 ggtgtcttaa atacctttac tagtttaggt ccatagaaat ctgatattgg gaaagctttt
    82981 ataaaagttg ctcctaaact tagtgcgtct actgcctcag tcaatgatgt acatcctgga
    83041 gcataaggaa tctgatatct attgcaaatc ttcgctacac cttcattgta atttggtgca
    83101 ataataaatt gagctccatg taatatagca tgacgagctg tttcactatc caaaactgtt
    83161 cctgctccca cacaaagtgt ttcaccatac tttttattaa gcccttgaat tatttctcca
    83221 gcattattta gggtataact catttctata actgttatac caccttttat acatccttca
    83281 gcaatttcac atgcacggtt aagattttct tctcttacaa ttgcaagagc cccacattct
    83341 gacattcttt tggttatatt catctttttc atattatcac ctctatactc atcaaaccac
    83401 tttacttatt cattaatttt agtcatgttt tataatatat atattaatta tataccagtg
    83461 taatttccct atttatatta tctattctca ctacttttat taagtattgt cctataattt
    83521 tcaactactc gtttaatttc ttcaagtact tccccagttg gttcagttac aggaagtcgt
    83581 gcagttccaa cattaattcc attcaagaca atagttttct tcataacaga tggaattgtt
    83641 ccaagtttca gtatacgtcg aagttcttct atactacttt gagctttttg agcttcttcc
    83701 aaatcccctt tcataaagtt ttcatagata gagataccaa tctctgtgag gaagtttgtt
    83761 gttgctgcaa cagctccttg actaccagct tttagactat ccagaataag tgaatctgag
    83821 cctgaaaaca cactaaaatt ctcattcttc gttgcttcaa tataagcttt catgttgtca
    83881 agtttaccac tactatcctt aattccaaca atattcttta tctttgataa ttcacgtact
    83941 gactctggtt caatattaat tccagtctta cctggcatat tatacattat aataggtaaa
    84001 ttaactgaat tagcaatagt tttgtaatgt aagattaatt cctgttgtgt tggtgtaaca
    84061 aagtatggtg taataataga taatgcactt gctccaatcg cttccattct cttagataaa
    84121 tctacaactt cacgagttga attaccccct gttccaacaa aaacaggtac acgattattt
    84181 gtatgattaa taacaatctt tgcaaattca actttttcat catctgttaa tacatgacat
    84241 tcaccattag tgcccaaaat aaataatcca taaattccct tttcaatcaa ataatcaatt
    84301 aattgacatg ttgcttgtga attaatattt tgattttcat caaatggtgt tatcattgca
    84361 catataatcc ctttatattt cataaaatta tattccctct ctaatagact ttccaagact
    84421 tcctgctgga tgccacttca aatactgctg tgtattaaga cctttagcat attgtaatac
    84481 aacacttaat gattgtaata ttattgtttc agctaaaatt gaagcacgag gagctttatt
    84541 aagacaatct ccttcctgtt taacacctgc aaacaggaat atatcagaaa tattttttaa
    84601 aaatgaactc tcattaccac ttacaccaat tatctttgct ccatttactt ttagagtctt
    84661 aagagttgct tttaactctt gagtttcacc actatttgat attgcaataa caacatctcc
    84721 ttcaactact tgaccacttg acccatgtac tgcttctgta ccatgcaata tatatgctga
    84781 cgttccagta gatgaaagca atgatgaaat atatcccgat acatgtcctg gtttgccaat
    84841 accagtcaca tgtacacgtc cgtgattttt ttcagcttca agaattaatt cgcatgcttt
    84901 atttatagat gtctcatcta ttgaggcaat aaattctgac aattcattag atatattatc
    84961 taaaaattca gataatgtat tttccataag atgtatcctc cttgaaatca tagtaactat
    85021 gactatactt ttatataatt tagtctaaat aggttttata aattgtaaaa tattatgtaa
    85081 tatcgaacca actacgttgt aatcaatatt agggaaagtt gctccttcta taccaagagt
    85141 cccataaact ggatatagta taactggcaa aaatgcaagt aataacccca caacaaatga
    85201 cccagcaata gcccctctcc atcctcctga agtattgcca aatattgcag ctgtacctcc
    85261 tgagaaaaaa catatgtgag cagctggaat aattactaca ggaaatatac taggaaatga
    85321 tgccataata gcaattgcta atagaccagc agcatatgct gatataaacc caataataac
    85381 tgcatttggt gcatatggaa atacggttgg aacatctagc gcaggacgtg aacctggaat
    85441 atacttttct gaaatgatta caaatgctgc agttatttca gctaagaaca tacgaacacc
    85501 tgacatcaat attgacatac ctgccacaaa tgtaaatgcc tctataagcg gaaaaaccaa
    85561 ccaatgtgtt gaaccagcaa tttcttgagt aaatgcttga ccagctttta atgttgcaat
    85621 ataaaataag attaacataa ctatggatag acccattaag aagtctctga atattgataa
    85681 ccacttagga aattctatag tctctgttgt atcatcttta tgttttgaaa ataaacgccc
    85741 aatataacct gataaaccat aaccaatcat gttaaagtga ccaatagctt gttcgtcgcc
    85801 acctgttaat tcacgcataa atggttgaca gaattgaggt agtgcagcag acataaaccc
    85861 taagatagtt ccacctatta aaatagtgat tgtattatcg aatccatgtg ctttcataat
    85921 taaaactaat acacaagaaa agaacaaact atgacctgtt gtaaagaaaa tattcttaaa
    85981 ctttgtaata cgtgcaaata ctaaatttaa tatgaatcca agaattaatg tacatgaaac
    86041 tgcaaaacca tatgtacctt gtgcaagtgc tgtagctgct tctggtgaag ctataacacc
    86101 agtaattcca aagccatgtt ggaacagttt attgaaattt tgaagtgctc ctgtcatagc
    86161 agaggcacca ataccaaata tcaaaaaacc gataagtgtt tttgaagagc ctgtaaatac
    86221 ttcaacagct gatttctttt gaagaatcaa tcctatacat gcaactacgc caagcaaaac
    86281 agcaggtgta ctcagcaaac taataataaa ctccataaat attcctcctt atcatcttaa
    86341 atttatccct cttttgaagc aaggaatttt tctagtgctg tctttatttc attacggtca
    86401 acaatattgt gaatcccaat tatatcaaac ttcaaatttt tattttttaa ttcttcagca
    86461 acatcaatta atgtttctac agcatctcca ttgaatccat ttagtgaatc caatgaacca
    86521 tgctctactt caattggaaa gttattttcc ttaataattt gttgagtctt tatttttaac
    86581 attaaacttg agccaactcc tgctctacat gcgattaaaa ttttatacat aattaaatcc
    86641 tcctttataa ttcgtgtgtt tttataaaat caataatttc tttagcttct ttagcactat
    86701 ctaaaacctt aaaaaactca tcttcttcca atagttcaac tagctcagac atagcacgta
    86761 aatggccatt attgtctatt gcacttagac aaaatacata ttttacaggg tcgttttcgt
    86821 tattcccaaa ctcaatagga ctatctaaag tagcaatgcc tattgcaatc tcttttgacc
    86881 cagcttctgg tctagcatgt ggaagtgcaa catgttttgt aattactatg tatggtccag
    86941 atgcttttgc tgagttaatc atagcatcta catacccttc agttactttg ttattttcaa
    87001 ctaatacaga agctgactgt ctaatagctt cctcccaatt cttagctttt acctttattt
    87061 tcactagtgt ttcattagta atctcactta gcataggccc ctctccttcc ttagatgtaa
    87121 aattctctat ctgtgtaaaa taagctaata gctcacttga aagaatactt tcagaggtta
    87181 catttgcata tttttttatt atatccataa cctcatctat tttaggttgt cttaaaaaaa
    87241 tatcacctaa ttgaatatac acttcacgtg taatcttata tttttctttt gtggtcataa
    87301 cagggcttac tttaattact ggtacatctg tttttaaacc ctctgcgtta taattagtag
    87361 taaatacaat atctacaggt tcacttatat tttctaatcc aactgattcc gacattggta
    87421 taaagtgtaa gtcaggaaat aagtttgtaa gttctgcatg taaaatagct gaactaccaa
    87481 cgccatttga acaaactatt aatgctattc tttttctaaa accatcaaat tcttttttat
    87541 ttgaaaaaag tgttgcaaag tgcattgtaa gatatgctaa ctcttcttcc tgaatttctt
    87601 ctccaaataa tccgcaaaac tctttcattg cattacttac aattctataa actaatttat
    87661 attcttcttt tactttttca caaatcggat tataaatagg taatttaaat aaaagtctat
    87721 agtaggcagg tctaaaatga gaatataatt gtttaaatat tttttcttgg cttatatagt
    87781 aaactccgct taaatatcca aactttgtca tcattttatt tacaattttt gaaattacat
    87841 ccttatcttc tgtatcttct tcataatttc ctactgatat acctaaaatc caagcactaa
    87901 tatacattat attgtgaggc tttattttat cttcactccc atatacttct aataattcct
    87961 tagcaaattt atactccttc attgaactca taactgaaat attaggaata tctacatttt
    88021 cctgagtaac tattctagtt gaatacatcc ttgcctttag aaagataaat atatatataa
    88081 attctattaa tctatcttca acaaaagtaa tttcatattt ttttattagc tttaatataa
    88141 tttttttagc ctcttcaaaa ctatctaaat tatattcttt aataaaaata tcaaatactc
    88201 ttgaactttt ctcattagac aaagtttcta taatgttttt aataagcact ctcctaattt
    88261 ccatctcatt gccaactatg taatatccat ttatacgatt gttcttaact ttaatgttct
    88321 tcttttcaag ctctggtatc aaatccttga aatcaagatt tacagtagac ctacttactt
    88381 ttatagaatt tataaaatga ttaattgaaa tatcatccat gttaataaaa agcattaaat
    88441 acatatataa aagtctttct gtcttactaa aataataagt attcttagaa tagttttttt
    88501 ctaaaatttc tttaattgct ttttttgttt cttttctaac gataatatct ttatcagctc
    88561 ttaaacatat aagtggtaca ttttttactt taagcatgtc attgatttta tttattctat
    88621 aagtaatttg tctctttgat gaattagact cctcttgtaa tccattagtt gtaatcaatg
    88681 tgctatttaa taaaatctgg agaattgata caatttcttt gtccactacc attaacccct
    88741 actttctcat taagattagt cttcatatta tcattggatt ctttcatcac ctccacaata
    88801 cttattttat ttgagaattt tatcgttttc aatttcattt aagtataact tttgttttag
    88861 attgatacaa aaattaaact tctctaaaat agatactata atataactgt agattttata
    88921 aataaaaaaa gtttctttag acaaagaaac tcaagaaaaa ttgatttaaa taataaaaat
    88981 catattgatt ataaataaat tactacaatt aaaaagcaca ttaatttaaa ataaaattga
    89041 tgtgccttat ctataatata atatatttaa tctaattttt aacttggaat ttaacatcct
    89101 tttttatgaa atcaacttat gtacatatac aattcatact ctatttttat ttcatttttc
    89161 taagtgtttc ctctaatgaa atacacttcg catatctttc attccatata aattcattgt
    89221 agtatttata tgattgttct gctgacataa aaaaattgtc aacagttgta tttgaataag
    89281 ctggaactat tatattaaat ccatgttcaa atccacattt tatagtggca tcaatacaat
    89341 aatctgtttg gagaccagca ataataatat ctttttcacc attatttgtt aggtattcta
    89401 atagaccagt ttctttaaaa gcactattta cttttttatc aaatattttt tctccattac
    89461 atggtttaaa tttttcgtat atttcaaagc catttttacc tttagtcaat tcattttcaa
    89521 ctccatcatc atgacgtaca tatattactt ctatattatt ttttctagct gtatcaatta
    89581 aattttctac atttactaca aattcattaa atttatataa cctctcgttt gttattaact
    89641 tttgtgcatc aacaatcagt aaaaccatgt ttattcctcc ttggatgttc ttctaataat
    89701 ttctttatat cttaccataa agatatatat tactctctaa tatttttata taatacattt
    89761 cctggattta taactattaa tgcaattgca aatattaaat ataacattgc atagtaattt
    89821 ataagctcta ttaaatctcc attaattatc cctattaaaa aattaaatag ttgatgtatt
    89881 acaataggta ttatcaaagt tttatttaga ttataaaaag ttgtcattat aatactgatt
    89941 gatataattg caatcataaa aaatataata tattttatta aatcaagccc tttgaatcct
    90001 gttgtaaacc atattggtaa atgccacatc ccccaccaaa aacctactat tatggatgct
    90061 tttaaaggag aatgtctttt ctgaagatga ttttgaacaa atcctctcca acctaattcc
    90121 tcacctaatg atcctgcaaa taaatttttt aaaaataaat atataaatgc tccccatgat
    90181 gaaactgtaa agttaggcat tattccatga tttttagatg ctaatataaa tataactact
    90241 acagctatta ggacttgtat actaattatt atagatactg ttgaaaattt aagtttattt
    90301 ctaaatctat cttttacgtg tactaaaaat ttcttacctg gataaatttt tttaaataat
    90361 atcataaatg caaaagtgga tgaccacgct gatatacaca acgcaatgtc agatatcact
    90421 gttggaagtt ttaacattat agtcactact accaataaaa aaagtggtaa aaaaattata
    90481 tttgttagaa taataaaact ggctataggc ctttttaatg atttctctgt tctcataagt
    90541 aatcctcatt tcaaattaat atttaattgc tatataagtt ataactgctt atatcatgag
    90601 tttaaaccta tgagtaagtc ccaggtcaat gcttttatat tattttatag gtgcataaat
    90661 ctctaaaaat atacgctcaa tcccttcttc ataagtagta agcaatatat taacatagac
    90721 tattccaagt aattcacatt cattttctat tgctatttct cttaatctgt cttccacttt
    90781 attatcaata ttttctcctc cagttgacca tctgccatct tcaataatag tataaataca
    90841 attgggatga gatagaactt caccttctat gattttgttg tagtcatcta cttcccttac
    90901 aattataaat ttttcttcta ttataccttc ttcattaaaa tttattactc ttcttaaatc
    90961 agttaatgta actgcttttt ttaagttgtt tgtattctct tttagggctt catattcctc
    91021 atagttagta acatgtttta ttttaccttt tacttccaaa ggcttcattt cttttattgt
    91081 gtattttcca aaatatgttt tgattttgtc acaatcttct ttgactaact gaaccttttt
    91141 taagagaagc tttttatatt ctatctcttt tagtatgatt tgttccttct cttctagtaa
    91201 gagttctaaa ttgtttatac tcttactttt tcttatttct tgaatctttt taatttctat
    91261 atcaatttct ctataaaagt ttattgttgc aatatcatag atatcaacct gattatatat
    91321 tctatatcca ttttcatcat ttttcttagg atttactaat cctttgtcct cataaaattt
    91381 tagtgtatct ctagatattc ctaaaaattt agatacttgt ccaatcgtat acattatatt
    91441 ctcctattat tagataaatt ctttatgctc attaaacgta tttctattaa caattacaaa
    91501 atcacctaaa ctttgaagta tcaaagtcag catagtattt acaacctttg gaattactct
    91561 ttttatttca taatccaagt gtaaacttgt taatatgata cgttataaat actatattgt
    91621 ctacatattt ctaacaatga ttctttcact ttaagatgtt cttaaacata tttaactttt
    91681 atttttaaaa atttcctata cataaagata ttcctttcat gataacagtt ttattatttc
    91741 aactatctgc taccataaaa ggaatatctt aatctttaaa cacattctaa atgctctttt
    91801 aacaaatatt atcaaattat tctaattcta ttgtttcata tttattagtc ttagttttat
    91861 ataaatttaa atataaaact atatattcac ctacttttaa ggataataag tcttcttcta
    91921 ccagtaagag taaatgcctc ctctacttat cacaaactat aatttttatc tcattggtat
    91981 atatccacga tactgtgagt atgcatccat agttgctata tcacctaaga atactgatgc
    92041 gatattgaat tgtggtttta aatatgggaa ctcctcttct tgtgcccatt ctggtttttt
    92101 aataaacgat tttgtctctt caaccacagc tttataccat tcttcttccc cttcaaacca
    92161 tagttctgac acacggtcaa aagcagttgc tccataatta atcattattt tactactgac
    92221 aaaacgatta acatagcaac agtttgtaaa gtatggcact acctcatcat agaaccattt
    92281 ttctccttct tctttagaga taccatctgg atacttaatc ataaattgcc aacgatagtt
    92341 tggtccatct tgtacagtac gtccttttcc tctaaagtct tcttcccagt ttattggaac
    92401 aaaggcaaat ataaatggtg gacatccatt atctccacct actgcacgtc ctgcatctcc
    92461 actttctgca ttttcatgaa cccttttatt ttctacatct ggtatacacc cttgccaacg
    92521 tagaacatcc ataggcatat attctgtcat aattctattt gccatctcag gcatatgttc
    92581 atctacaagc caataatgtt ctgttagttg catcttacgt gcaccaaaac gctcaccttc
    92641 atttggtgta ggatatgctt gataaaaggc atatttagta caatatggtc caaaagtgct
    92701 aatactatct ggaatatggt gacgatataa ccagtccatt agcttaggtc tatattcttc
    92761 cttggcaagt cctacatata ttaaacttct cattatttta aattcaaaac ccatagccat
    92821 tctcctataa tcaaagtata ttcacatgct ttcaatttcc ctttttccta tctttactaa
    92881 aaatatatat tgtaaacaaa tctacacctg cacccacgta ccatactcct actgccatag
    92941 ctacagcaat ttgaatacaa atatcttgta aattaataat attttcacct gtcataatag
    93001 ttagacctat agcccaacca caaagccatg atggtaggaa aattattttt tcaaataagg
    93061 atgcaattac aactgcaaaa aaacctaata tactaagtgt taaaaataat tctagatttt
    93121 gattgaaatt catatatccc ataattaaaa tggctaacac tgcccataaa tctccacacc
    93181 aaaaaccaaa cattattttt aatccatctt tttgtttatt accattagtt acatataatc
    93241 ctgcacagat tagtgctaca gctccagttt ttattcctat ataaggtgct aatactgccc
    93301 ataaaggagg tagtaaagca atccccatag acagtgttaa tatttctttt ttctttctat
    93361 ccatttccta tattgtaatt agtagcttcc ctagcttgcc ttatctccaa tagcttaatt
    93421 actatttgat ttacaatcat agatactgca aaataactta aatatagtgg tataaatata
    93481 acaataaatg ctggagttaa tctaaccttg taatatgtaa gtaccaaaaa aataactgct
    93541 aaaataactt caatttgttt aaaacttgac ttttcattca tacaataagc ctcctataac
    93601 atctaacatc ccttaaaaaa gagtcttagt attttaatta ttatcctaat gaaactccag
    93661 cttgtttttc tttagttaat gtctctataa aattataaga tgtttttctt tctttaaatt
    93721 cttgtgtttt acgaacttct gcataatgac cttccatttt cttaatatca tcaccatgta
    93781 taaacttacc tggtaaagta tcatgagcat gacctaattg ctcttctgga aaactaaata
    93841 tagtttttcc acttatagta tctaactctc caactatacc acatagagca caaattgcct
    93901 ttttagtacc tggctcaagg tagaataatc tattgtggca atgtggacat acaccttctt
    93961 ctccttgata tgaagctttt tcaaaatctt ttgctgcttc aactatattt aaaccaattt
    94021 gatgaacttg aacaagcctt gtatcatcca ttactaattc ctttgcccat gggaaccaag
    94081 cattatctat aactttccac attggtatga gagctagcat agcatgttca cattgaactc
    94141 ttgtacccca gtcagaacct cctattccca taaatgatat tactttatca ttaagcattc
    94201 ttgaatctgg aatttttcct cctatagctt ctgcaacttt tgttcctata atgttatttc
    94261 ctctatctgc tctgggtcca aaacggtcca ttatagtatg gaataatcct gatgcccctt
    94321 cttcaaaaat agggtctgaa actactatac catctgcatc tttcattttg tcaagcaacc
    94381 attcaaaatc atcttttaat acacacatac tacctttccc agataataaa gttttaacac
    94441 acgcacaaca tccagtacaa tgtttaatgt taatagatga catttgaata aattctactt
    94501 cagcccctgc ttctttggca cctttaagtg caactttaca cattgtgtca ttatttccat
    94561 tttttgttcc aaaagaaata cctaatattt tcattttcaa ctctccctct ttagtattta
    94621 tttaatcttc tttcattttt aatatataga atccatcatc taaagcatct atgatgatgt
    94681 agcctctatc atcaacgata agatcttctg ttactgccaa gcgtggtcct gggaatcctg
    94741 ggaaataaga ttcttctggt gttttatttg gatttggtgg tataaaatat gctagctctt
    94801 tgatataata tgggtctgat acatcataaa cccttagccc tgcatggaaa taacagcaat
    94861 atactctatc tcctctttgc tctaaccatg gcttattatc cattggttca tgaagattat
    94921 gtggaccaaa tggccctggt tttcctaatc ccgcaacatt aaagttagga taagggaaat
    94981 cttttggaac ttcaggatat ggaaattgag caattaatgt tggttttgtt gggtcactaa
    95041 catcaaccat atgtatatta ttcatagctt gaacatctgt aatgttatct ggtttaaaga
    95101 actggaatct ttctccctca ttttgaacaa cgactaaatc tcttcctggc aatggtaatg
    95161 ctgtatgagt tcttgcacct gcaagtctac tagaaaatgc aggcgtaaat ggcaattcac
    95221 ctaagcatct tggtcttgtt aaatcttcaa catctaatac aactaaacca gctcctccat
    95281 aaccacaata tgcttttccg tctcttacaa atggaggtcc atgaagccat cctttatcca
    95341 taaattctgg gcaatgaggt gctcctgcat caaaagttct atttggatat ccatctgcat
    95401 attggtctgg tctccaccat ttacctattt ccactggatt agtaggattt attatatcta
    95461 tgaccctata aatcagacct tcaaagccaa cacaatcact tgataaatgt acatatcttc
    95521 caccattgta catgaatcta tgaacaccca ttacatgctt taagccacaa tcccaatatc
    95581 ctaaaaactt aggatttaaa gggtcttctt ttaaactgta tattctaatt cctgcttcac
    95641 acttaatatt tgctaattta gcttggtcaa caagtgctcc tggtccactt ccacaactca
    95701 ttgctactat cattaaatca tctgctattt gaattttggg agttgttgtt gtaggatact
    95761 ctttagggtc taacatttga aaatgtttta taaattgtgg attataaggg tctgtaatat
    95821 cgctaatcat tactccattt tttttatttc ctccaaaaca gcatccatat aaatagtatt
    95881 tttcatctct tttgtacaga gccatttgaa acattccaca agttccatct aagttattaa
    95941 aagaacaaac ttcaagattt ttaatatatc cgttatttcc gttgcctttt gcataaaatt
    96001 tatcttccat tttttctccc ttcttattta aagtattatc aattgatata ctttcatttt
    96061 atgagacaaa cttacttaaa tccaatatcg ttttcattgg aatatataag ttattcttat
    96121 taataaattt ataaaatcta atgtaaagat atacttaaaa catatatttt tatacaaata
    96181 ttttctaata ttctttaaaa gtaaattttc ttatactata ataagcttta attatagata
    96241 aataaggttt acaaacaatc aagtttaaat aggggtgatt atttgaatac taaacaatta
    96301 gaatatttta tatctgtagc agaaaatcta agttttacca aaacagcaga aaaattttat
    96361 atttctcaaa ctgctgttac acagcaaata aaagctttag aagaacaaat aaatgtaact
    96421 ctatttacaa gaagtaaacg tcatgttgaa ctaacaccag ctggaaaagt ttttttatct
    96481 gaggcacgta ctataataaa aaatatcaat gatgctattg caaaaacaca acaatttgca
    96541 catggttttt ttggaacttt gagcattgga accttaatag gatatgaaaa aaacaaactt
    96601 caacaatatt taaaagaatt ttctaacaca taccctaata tatctatgga tatttgtact
    96661 aatgagataa ccgaactttt aaacttagta aaaaataatt ctatggacct cgcttttgtt
    96721 attaatccag aaaatcaacc attaaaagat tttgaatata aaactgtaga aagatattct
    96781 ttggtagctc ttttacctcc tggtcatcca ctttacaatg aggattctat cgatttaatt
    96841 gaattacaac atgataaatt tatttttgta aaagaaacag gggatgagta tggacaaaag
    96901 tcaatgatac agaatagata tcgtgaagca gggtttgtac ctaatgtggt acaacgttca
    96961 aataatctta atactattga atcattggta tcttctaaca tgggaatatc cattttacct
    97021 tcattttgtg ttacagatac aatgatagaa cgtgatattg caatagtacc tataaaagaa
    97081 gtagaaaata gaattgaagt tgtagttgta tggaataaaa aaaatacaaa tccagcatta
    97141 gaaaagttca tttctataat ataaaattaa tcaatattaa cgataaaaat agcattaacc
    97201 attttttcta tagttaatgc tattttctac tattttatta tttaactttt aatttaatat
    97261 ttataatcgt taaaaataac tctgtttaac aaatataagc aagtcaaaaa tgtgtctaaa
    97321 aaagataaaa attttattat atacaaatgt attatctcaa tatatctatt ttttcattgt
    97381 tcatcagtct aagtacatga cctgtgctta ctaaagaatt atccccataa gttgtatgag
    97441 ctaacaccga actagcaacc ccaaactcaa ctatatcttc actcttcata ttttccaaat
    97501 atgaatatat aattcctgcc acatatccat ccccagcacc aactctgtca tatatttcta
    97561 acttatactc cctactttca aaataaccat catcatttga tatatatccc tttataaatc
    97621 tattattcat atcatcaaat cttctcatag ttccagctac aatacctata tcatactctt
    97681 ttttaatcaa ttctgaacta gattttatat ttagactatc tatattaagt atcttattta
    97741 tatctctata actagcaaac agcccatgac aatatggtag tattttctta taatcattta
    97801 ctaaatcatc ataagtcctt tctggattta atgattgtct aaaattaaaa tcaaagaata
    97861 cttttatccc cttttcataa gattttctag ctagttctaa agcaatctct ttaactgaat
    97921 ctgtaagttg catagcaata ccacaaatat ggactatatc catttcttct aaacatttat
    97981 caatatcata atcttgtaat ttactctcac aaaatgaact atttaaccta ttcaaataag
    98041 tcacttcaga aggtctttct ccatacccat tttcaagaaa atacactcct atatgattcc
    98101 ctccatatgt gataaagtca tcttttactc caagctttct tatatttgca ctggatgctt
    98161 tacctacatt attattaggc aactttgtca acatataggt attgtatcca aagtttttaa
    98221 gtccagataa tatatttaat cccgtgcctg taattatata atttagttca ttggtttgtg
    98281 ttaagaactt gtagtcaggt actgaaagtc tcatcattat ttcaccaaaa gctaatatat
    98341 tcataaatct atcccaataa ttctttcatt attttataaa gtactcctat atcttccact
    98401 ttcgtttcac ctgtttcttt atcaattatt gatgtataaa catgaggtat aactttttct
    98461 acaccagcat caagtgcaat ttgaactatc tctttgaagt tatctaagtc tatacctcct
    98521 gttggttcta aataaaaatt atgctttgca caagcttttg caacttctat atattcatcc
    98581 tttgttttaa gccctcccat tggaaaaaac ttaattgagc ttcctcccat atctttcatc
    98641 atagctattg ctgtttctat aggaactata ccatcttttt cttttgaact taatggacct
    98701 gtggatattt ttacaaatcc tggtttacca gttggagaaa ctaatccatt tattatacta
    98761 taattttgcc caagcaatgc tctagacgta gccacacctg taaacacttg atttatatgt
    98821 tgtggctgaa gttctttaga aatctgagat accatatttg actgatttgg gtctccagct
    98881 ccaagcccca cagatattgc attatctatt tcctttgagt attttttcat atcttcaata
    98941 gctgcttcta cagtactgta attctttgat agtactccta tcaatacatg cccgtcacaa
    99001 gcatcatata cttctttagc attttttatg cttcctgcaa gaacatttaa acaaactcta
    99061 tttttataat attgtggtat acaattcata tttatcccct ccattggtaa aatttaattt
    99121 attaaatcat tataatgtca cttactctac actctaactt tctactatat tttttatcct
    99181 attataaata gtatctaaat cacttccagt tacacttctt atatcaatct caatcttgcc
    99241 ttcattagcc ttatagtctc tagtgtatat agctatctct ccacttctaa gttcatttat
    99301 aatttgttgt gttgacttat ttattatatc ttcattaaag tcaatttctc cacgaagtat
    99361 ttctctacct gctgaatccc tagttatact agcactcact ccctttatag tatttatctt
    99421 gtctataaat ggatttagct tgtcctccat ttcttttaaa gttactttat cattacttat
    99481 atatctctca attgcacatg ttagacctac aatattttct tttcctattt tcatagctct
    99541 tcctataccc tttgattgaa gctttacatt atctatgtat tttttcttac ctattactaa
    99601 ccctgagcta ggaccctcta tagccttagc accactgtat atcactaggt ctgctcccaa
    99661 ttcataatat acatttaaat cttcttctgc tgctgcatct actatcaaag gtaaattata
    99721 ttctttagca acttgtactg catctaatac acttagcata ctcttttgaa cacaatgatg
    99781 agatttaata tacataattg ctgctgtatt ttcatttatc tctcttatta tatgttcctt
    99841 gttacacata ttagcataac cggcctcaac aacttctcct cctccaagtc ttatcattac
    99901 ttctactgga actccataat caacattatg tccctttgga attattattt cccttttaac
    99961 ttgtttctta ggattattta cattgtaaac tagactcata tcatcttttg ctatcattgc
   100021 tcccacactc tgtgcaatcc cagcagatgc actagaaact attagtgcac tttcacaccc
   100081 taataaattt gctatatatt cacctgtttt atttataagt tcttctatta taaagaaatt
   100141 tttacaccct tcacctattg cttcaataac ttccttatct actgttgata ctcctagtat
   100201 agtcattttg cctgaagcat ttataacacg tcttacagag tatttttcaa atatactact
   100261 catacaatag tttctccctt ctactcattc tctcctatag acttacctat atttaaatat
   100321 tctccattga ctactactgc tcttggcttt atagacgtac ttgtgattac tgacttattc
   100381 aaagaatctt gaagttcttt ttcttcatta accacatcaa atatagttaa atcagcatca
   100441 tatccttctt ttattaaacc tttatttttt aaacttattg catctgctgc atttttagta
   100501 actttatcta ttatatcttc aagtgaatag cccatatata taaacttttc cattgttgta
   100561 gatagattat acactggacc atttattcta tttttaatat atatatctgt acttatagtg
   100621 tctggaaaaa ttcctgcatc cttagatttc attgcaatat ccatactaaa actttcggtt
   100681 ccatgaccta catcaaggat tatacctctt tctctagctt ctatgatttc ttttttaacc
   100741 tcattgcctc taagtattcc atttggcttt ccattatata tatgggttaa tatatctcct
   100801 ttttccatat agtcaaatat atcctctatc gttggaggag aactcccaaa gtgaaccatc
   100861 ataggtagat taagttcatt ttttattctt ttagctactt ttaaaggttc aacatcattt
   100921 gaaattacaa cacttttact cattctagct ttgattccaa caacaaaatc tttgtatttt
   100981 ttaactgctc ttttaacttc atattcatca atattcatca tacttgaaag ttcatcttga
   101041 gatgttattc cctgcttagc aatatttatt aaagcatata catttgtttt atatttttta
   101101 gtatcttcat aaaatttacc tatatctaaa gctcctgttg ttcctgcatc tactacagta
   101161 gtaactccac tttttattcc aacctcatct ggataatcct tataaaggtc tagtctttcg
   101221 tagcaatgcg tatgtatatc tatccaacca gcactaataa atttctctcc atctaagttt
   101281 ataatttgtt ttgcctgata cttagaatca tctatctgat tttttacttc tattatttta
   101341 tcgtctaata tagctatatc aattatactt ttatctactg tttttccaca ttttattaat
   101401 atgtctatct tcactttact ctccctctaa aataatctta aatttactcc aaggttcaat
   101461 aaagtctaaa agtattattt cgtcttcctt tattctaccc accttatttt ttctttcatc
   101521 tgtacaatct tgaagtatca actgtaattc ccctttatac tttccaaagt cattattacc
   101581 aatcactaca tctcctcttt taaagaggtt cttattatca tgtttaggga aattttcttt
   101641 agcatatttt tttcttactt ctgtagatct tgctacctga ttagttatat ctcctcttct
   101701 aaagtgttgc tcatttacca ttattgtctt ttctacttca gaagtttttt cttcagctac
   101761 tacattaaat acaacttggt attcatttac ttcagacatt ctttttaatt catcttcact
   101821 tgcatatgca ttccctacaa ttacatcatc aatcaatcct gttgcgaata agtgcttagt
   101881 tgctgtagca atatctaagt ttctatgcat ttcaagcgta cacagcccat catttatatt
   101941 ccaaggccct attgttgcgt attttgaatt aacaaaagca gcagttctta ttccatactt
   102001 tttaaatcta tttgaacatc ttacaaaaaa atcatatggc aagcctgtac ccctttgagg
   102061 ataaaaattg tgacaaccat atatattatt tacatttggc ttgtaagtaa ttatattatc
   102121 caagtatgct acatcattac tcatatttag ttccactttt aaatcatatg gattgaaaga
   102181 aatcatagct tctttacttc catcatatcc atagtcaagc cttattccac tagcatttaa
   102241 ctcactaaaa aatgttaaat catcataaga tatttgtaat atatcaaata tgtttggagc
   102301 tatatcaagg attacttcaa atcctaattc tcttgcatag gttataattt ctttaaaatg
   102361 ttttttaact tcttccttag gtcttgtaat tgaaagcatg cacataaata ttcttttaaa
   102421 tccgtatttt gaagccattt ttatatatgc cttatcatct tccatgttac tatgctctgg
   102481 atatactgat attcctaatc ttctttccat ctttctcctc ctcaaattac attatttaaa
   102541 atatataaaa ttaaaggcaa aggtcattcc tcctaccttc acccttaata acttataagc
   102601 tttttctata ttttatatag tacaaaacct ctatatctat gtatttttat aaattttcac
   102661 tcatttcttc ttgttctctt tgtaattgtt gtttttcaaa aactttgaag aatggataat
   102721 aaacagcaaa tgatatcaca aagttgatta atactaagat acctgctagt atactccagt
   102781 tagtactcat tactgctgct attggtgctg gcattgcaaa tggtaatctt gctaccatca
   102841 taggtataac ccctgtaata gtaagaacat atgatagaat tgtcattatt ataggtccaa
   102901 ttataaatgg tatccctagt attggattca taactattgg tgctccaaat attataggtt
   102961 catttatgtt gaataaccct ggtaaaaatc ctaatctacc taaacttttt agatattgtg
   103021 acttagaaaa cataaacatt acaactaatg caagagtagc ccctgctccc cctatccata
   103081 cataccactg taaaaattgt tctgtaaata tgtttggcat tgcatgagct gatactcctt
   103141 ctgtgaatgc agttatattt tctgctatag acatgtccca tataggtctt attactggcc
   103201 ccattatagc tggaccatgt attccaagta cccagaataa agttattagg aatactgtca
   103261 gtaacccacc acctaaacta tttcctgata agaatccttt taaaggtgat aacatagcgc
   103321 ttagtgcaac acttatatca aatcctaaaa tatgtcttat tacccagaat aacattaaaa
   103381 ttactgctgt cggtaataat gcagtaaatg aatttgaaac ctctactgga actcctgctg
   103441 gcatcttaat tgtaatattc ttttccttca taaaacgata tatttcaact gtaattaacg
   103501 atgttacgat agctccaaat aatgatggcg aattaagttt tgccatatcc atccatctac
   103561 cagcttctat aactccacct actggttcaa ctacttgagt tggaactatt gtagaaacta
   103621 aaaatgccat aactgcaagc ataccaacac ctgttgtatc taaatcgtag cttttagcaa
   103681 gtgatgatgc tatcccaaaa gtagcatata gagataaaaa tcctacagta tatctaaatg
   103741 gtatatctaa tattgcttta aatggagcta taaaatccat ataagcatca ataggtatgt
   103801 ttaataatat tgtgaaaaat gaccccacta ttgttagtgg taatgttgct attatacctg
   103861 ctcttacagc tctcatatgt ctctgattac ttatcttcgc tgctacaggc ataatcttgc
   103921 gctctaaaaa acttgcgaat ttttccatag ttatccccct gtattattga tattatcctt
   103981 tatttataat gcaataacga tttcataaca taaactaatt tttatgtaat tgataatatc
   104041 acttgtttat taaaaatatt ataacattat aatgtttggt tgtaaacatt ataatgttat
   104101 aatatttttt atttttacaa ctaaacaaaa atcctgagca tattatcatt tcaataaact
   104161 caggattctt attatatttc gtatttaatt acatagtttt gtacttctgt attatatctt
   104221 gcaaatgata gctcaactat attatcattc tcatcatagg tctttctttt tcttcctaat
   104281 aatatgtctt tagctagatt taaagccttt gatacctcta gttctgattc ttctataaaa
   104341 aattcatctt caaatctagt tatatttata tttctcctat ataagtacat atataaagaa
   104401 ctttcattat taaaactttc aacagttaga ttttcatcaa aaggaatata atgagtaaaa
   104461 aatatatatg gcttactatc taaataatac attctagtaa tcttgctaca tttttctcca
   104521 aatatactaa atacttgtga atttgtatca tttattattt tttcaattga aatagtctct
   104581 ttagataact tatgaccttt agataaaagt atacttgaaa aagactctgc ttttgatagc
   104641 ttattaaaaa ggctattact tattactttt gtcccttttc cacttttttt ctctacatac
   104701 ccttctgatt ctaatatctc aatagctttt ctaatagtaa ttttactgac tccaaactct
   104761 tgctctaact ccctttctgt tggaatattt tcatcaattt tatattcgtt atttaatatt
   104821 ttttgcttta atatatctac aacttgtata tataatggtt gatttcttaa catgattcac
   104881 ctcttaaatt atatgttata atattataac atataatctt atattattaa taataaatat
   104941 ttattaactt taaactaaat ataaaaagag tcctcaaaat aatcctaatg tattactcac
   105001 taaatattga atcaataatc taacaattag tgtgctacac ataatgtatc ttttaagaac
   105061 tctcttaatt tattatcttt aatttttatt tatcttgtaa tttcaaatgt aaatcaacga
   105121 tttcttcagc taactgttga aaattcatac cattcattag gtggtcctgt gcatgtataa
   105181 gtatgacact tatttcagtc ctgtttccac tagcttcgtt ttgtattaat tctgtttgat
   105241 atctatgtgc tttatttata acttccctag actcttttaa taattctttt gctttttcta
   105301 tatttccatt cttagcctct tttattgctt caaaagctaa tcctttacct tcacctgcat
   105361 aacctattat attaaaagat atttctataa tcttttcatc catcctttga ttctcccaat
   105421 ttatatatta aaaatacatt ataatttata ttacttagtg ttgttaagtt ctatcgctct
   105481 atttaaaaca gcttctccat taactgttcc atagtgcatc atatttataa cttctactgg
   105541 tatattatat ggcttagcaa tttcttgagc cttaggtaat acatatctaa cttgtggtcc
   105601 tagtaataat acatcacatt tttctatttc attttgtata gttgattctg gtattgccca
   105661 aatttgcgac tctataccat tttctttagc tgcactttcc attttagtaa ctaataaact
   105721 tgtagacatc cctgctgaac aggccaacat tatttttatc atatattttc ctccaaattt
   105781 ttattaacaa ctatataaac attataatgt tataatattt tatttaattc taccttaaat
   105841 gcaatatact ttcaatactt ttttgttatt ttaatattat taagttgcaa actaaaaaaa
   105901 accgtatcat ttatttatga tacggttctc cattatttat cctataagcc ctataaatct
   105961 gttctaacaa tatcaatctc atcatctgat gaggaaaagt catcttagaa aaggataacc
   106021 tataatcagc ccttcctaaa acctcatcag aaagccctaa agaacctcct attataaaac
   106081 agagactact attacctcta actgctaaat cactcatagt cttagcaagc tcttcagagg
   106141 ataaaccctt accatcaata gccaaggcta taacataact attatgcttt atcttcccta
   106201 aaattttctt tccttctttg tattttataa tttccatttc cttaacactc aaattctctg
   106261 gagctttttc atcatccaac tctataattt ctaacttaca atacttagaa agccttttct
   106321 taaactcatc aatacctaat tttaaatatt tttctttaat tttacctact actactatac
   106381 ttatattcat atatttctcc taaacttaat tttattacaa atctatgcat tactagaatt
   106441 tacaagctct tataaaatta tatctctctt tcttgatttg catattctac aaactcttca
   106501 aaaggtattg ctttgctata ataatatcct tgatatattt cacatcctaa accatataac
   106561 ttatcccttt ggtctatatt ttcaacatac tcaacaacta tatcaaaatc taaatttttt
   106621 gaaagattta caatagtcat tataatttca ctacttcttt tatttgtaag tatctcttta
   106681 actaatgaac catccaattt aactatatca aagttattat tttgaagata tataagagag
   106741 ctatgcccca tcccaaaatc atccataatt aactttattc ccaagttatg tatcgcattg
   106801 atacgttcaa taattatttg tgaacctgat aatgcaattt gctctgttat ttctatacct
   106861 aacatattag gatttatatc attactacta atgatatttt ttatttgctc tggtaactta
   106921 gggtcatcaa gttggtctgg agatatattt acagagaact taacaggatt tctcaatagc
   106981 ttttcactct tctttaaatc aatacatgct ttattaataa tatactctcc aagctcatct
   107041 aagaaccctt cttctttagc caaaattata actagtggtg gataaatgaa ccctcctatt
   107101 gaatgtttcc atctaagtaa tccctctgct cccacaacat ttccattata attgacttgt
   107161 ggttgataaa aaagctctat ttctcctctt ttcatagcaa acttcaagtc tgatgccaac
   107221 atttttgaaa ttgaacctat tttaccatta tggtttagaa gattaggctg ttcacctgtt
   107281 aattcatacc tttttaataa gtttgttaaa ttttctatat tatttttaaa catatatgta
   107341 tatctatttt gcgacatttt tataaacgga atataaatca taacaccaac acataaatta
   107401 aatacttgca acaaactacc tcttattgaa cctgtagaca tatatccact taaaaatata
   107461 ggtgaggtcc attctacagc tgaaactgta catggtacaa tacctgtaga catagccaca
   107521 taacttgtaa tgcttaagat tataggagta attacaaaag gtacaaacat aatatagtta
   107581 aaaacaattg gtataccgaa aactagcatc tcattgatat taaaaagagc tggtattgaa
   107641 gcaattttag ctaactttct tacatttata cgtttttcac taagaaaaat tgcaattact
   107701 aaacatagta aagagccaca tcctcccaat aaaaccattg tatcaaaaaa ggtcttagta
   107761 aaaatttctg ttggtaattg attattatta actaaattta tgttaattgc catactattt
   107821 tcaaataaat tttttgcgac ggtatctaat acattactac catgaattcc aaaaaaccac
   107881 ataaagtgca ttaaaaaaat aaacaacaga gcactcataa ggtttgttcc cattttatta
   107941 aaaacatttg aaaataaatt ataaaatata tcttgaaagt ttgaactgcc aattagactt
   108001 atcattatca ctctaaaaat agaaaacaaa aatactacta ttatgaaagg aactatagcc
   108061 gaaactacca tattaaagtc tgcatcagcc ccttctgtat gaaattttac acttgtaaca
   108121 aaagattctg taagttttac aaacaatata gaagatgtca tagaaacaat tatagatgta
   108181 aataaccact ttgtcttaaa tatttctata taagaattaa gctcattacc atgcgaaaat
   108241 actaaaaaag agcacattgc aactatagga acaagtactg tatacttgct cccatatatt
   108301 tttccataac tatagcttat tgttaataat attattaatg aaataattcc taaagtagaa
   108361 tcatttataa agttaagaat atttgtaacc tctccattaa acaagcctga taaatattct
   108421 tgataagcct ttattggaag attcaaaatt acaagagccg ttgaaccagt cataatagca
   108481 ggtatcgcta aaatcatgcc ctgctttata gagtataaaa ttttattatc ctcaacattt
   108541 tcaaaatttc tctttagcaa agttattcac ctctacttca tctcataaac attagaaata
   108601 tcatttcgtg atagtacatc tagttttaca tcttgtccaa ctactatatc atttgatgcc
   108661 aatactcctt ttgaagtctc atacgctaac tcaggaaaat tattttcttt actcaaatgt
   108721 gctaataata tagattctgt accttcatta ataagttcaa cgcagaaatt agctgcatct
   108781 tcattggata aatgaccagt acttgacatt actcttttct ttaaagcata tgtatatgaa
   108841 cccatcataa gcatattagg gtcataattt gattccaata ctactaattt agatttatat
   108901 agatgttttt ttatattttg agttatacat cctatatcag tagctataga cattttttca
   108961 tcactctctg tataaaaatt atatccaact gggtcagacg catcatgttc tattgaaaaa
   109021 ggtcttacta tgatatcacc taatgagtag gttttatcat tttcaaatac tttcatattt
   109081 ttatctttga tgtcacctaa tttgtccttc atagaacacc atgtttttat attagcaaat
   109141 actggtatat caaactttct tgataatata cctgctcctt ttatatggtc aacatgctca
   109201 tgtgttataa atattccttt taatttatct gcatctacac caatgtcttt aagacctgta
   109261 gttattctct tgccacttaa tcctgcatct actagtatat tagtattttt ataccctata
   109321 tagtggcaat taccactact accactccct actgaacaat actttagcat tccttcacct
   109381 ctttttctgc cttataaatt atattatacc aaaaaaacag agtattaaat aaaatttaat
   109441 actctgcaca aaatttactt acattcactg tttacttaca ttcacttata atcttattta
   109501 tatctacacc tttactattc catagttcca caaaagctct tccattagca tttttatgtt
   109561 tatacttatt atagtactca tttaaagtct caaagaatac tttatctcca acttcttttc
   109621 ttatttcatt aaatgctatt gcgccttttg tataaacatt caagctgtat tcagtagaat
   109681 ttttatactc atttgctggc ttaaatatat tttcgctcaa ataacttttt gtctgtatct
   109741 ccatagtttt tataagcttg tttgccatat ctttaccata cttttgttca aaataaacta
   109801 ttgtagaata ttcagtaagt gcttcatcta accagggttc acttatttca tcatttccaa
   109861 cagcagaata ccaccattga tgtgctgtct catgggcaat aacatattct agtaaaaatt
   109921 catttttttc attatataaa ctttggtcta tcataacaag catagggtat tccatccccc
   109981 ctataaaaaa gtcacttgct acaacagaaa attctttgta aggatacttt ccaaataatt
   110041 cactaaatat atttattgaa tcttttgcca cttcagttgc ttttttagaa agctttttat
   110101 ttaaattata tgtattgata gctactccct ttgaatctac tttgtttaca ttaaatttgc
   110161 tacttagtat aaatgcaaaa tctctaacgt tttccgcttc tatttcatat agcattttct
   110221 tattatcatg tttatcatca ataagttttc ctgtatgagc aattttatat ttatttggaa
   110281 tcaatagttt cacatgaaaa tcgctagtct cactataaaa tgggtcgcca atagtttcat
   110341 aactctttaa attccatccc ctttcatcat ttacacaagc tataggaaac caattagtaa
   110401 catttatagt attttctcca tatccaaatc ttccaattga atttggtatt tttacgttat
   110461 attttatatc taatgacatt ctttcatttg gttttaactc tttccctaat tctatttcta
   110521 atatgtcatt tttgtctcct ttaattttat actccatttt actattatta tttaatatat
   110581 tctttatatc tatatatcct tcgttaaatc cattaggata agcccttgtc atttcacttt
   110641 tttcaaaagg agcaaaatct ttcttggaaa aagcattcgg atatatatgg aaatatattt
   110701 tatctaagtt tgattttgta ttatttatgt agtcaacatt ctgattgcac attaacctct
   110761 tagtctcatc atcaaatata acatccatat tatactgatt tatttttgaa ttagtttttt
   110821 ctttgtatgt ctctaaactg tcatcctttt ctataaagca acctattatt aataccataa
   110881 atagaatcgc tactgataat gttcttctta ctttttggtt gaattttata accaaaatat
   110941 ctcctccttt tcaaaatgaa tacttttaga aaatatttac atgctaatct tgtgaccttt
   111001 tatttgttta cagacaaata taatataaaa aatgatataa tttaatctga ggtgataaaa
   111061 tgttttttaa agaaagcaat gaaatagatt taggtgaaat cactattccc aatatcttta
   111121 tagatatatt tatgccaatg gcggacgggt tatacgtaaa agtttatctt ttaggatata
   111181 gacaagcatg tgatattact tctaatccta agttcgacaa taattcaata gccaaaaacc
   111241 taaatatacc attgtctgat gtgttatctg cttggaaatt ctgggaagaa aagaagatta
   111301 taaaaataca tgacaatgga gaatatgata attttaatta ttcaatagaa tttttagatt
   111361 taaaaaattt ctatattgag aatatattaa gcaataattc atctataaaa tctaatacag
   111421 ataaggttgt atctacttct gaaaatccaa gtattagaaa aatgtttaat tctataaata
   111481 aaatagttgg gcgatatctc gacccaagcg aaaagatgag tattatggat ataatgaata
   111541 aatacaatat gagccccgat atgatacttt gcgcatatga atacgtcaaa gataaaactg
   111601 gtacatcaaa gccagttaaa tacattgaag gcattattag aaattggtat gattcaaatt
   111661 tatatacgcc aaaagatgtt gaagaaagct ttttggtaag aagtgaacga tatattttat
   111721 ataaaacgat tttcaatgaa ttgggatttt caagacaacc atcaaaatca gaaaaagaac
   111781 ttatggacac ttggtttgat aaatttaata tggatataga tttgataata aatgcatgtt
   111841 ctaagtctaa gaatatttca aacccaagta tatcttatat aaatggtata attaaaaatt
   111901 ggaatgaaaa aaatataaaa aatttaaatg atttaaagca aaaagaggaa gaacgtatag
   111961 ttaaggagaa tattaataag aagcagatta atactactca aaacaacaat acttacaaaa
   112021 aaactaagtt tcataatttc aacgaaacat tcactcagta tacctctgat gagctcgatg
   112081 agattattaa aaaaagtcaa aaagaaaagt ttaagtaggt gattaaatga atgaggataa
   112141 aataagaaaa atacttgcta aatatgctaa gagaagagat gataatgaac tcttattaga
   112201 acatagaaaa aatgaggtat ataatagaat ccctgagata aaatctatag atgatgaaat
   112261 ttctaaaata ggtctcagtt tagctaagat agtactttta aatcctaagt ctaaagatga
   112321 aattgtaaag aagactaaag agaatataga atctttaaaa gtaaagaaag aaagactttt
   112381 agctgaaagt aacatacctc ttgattactt ggaaataaag tttcaatgta tttcttgtaa
   112441 agataaagga tttttaccta atggagaaaa atgttcttgc ctcaaacaag aaattgtaaa
   112501 tgaagcttat aaaatgtcta atttagatag gattttaagt caggaaaatt tttcgaattt
   112561 taacttgaat atattttctc ctaagaaagg ctctgatggt gaaatatctc ctagagaaaa
   112621 tatgctaaat aatttaagta tctgcgaaaa ttttgttcat gattttaaga aggataatag
   112681 tgaaaatcta ctgttttatg gttctactgg actaggaaaa acctatatgt gcaattgtat
   112741 tgcaaaggaa ttgttagata aaggcaatgt tgtaatctat caaacttctt ttagaatttt
   112801 agatattctt gaagattata aatttagaag agacacaaat aatcaaataa gtgaagataa
   112861 ttataaaaac ttgtttgatt gtgatttatt aataatagat gaccttggaa ctgaacttaa
   112921 taattctttt actagtggag aaatcttcaa tattgtaaat acaagacttg ttgctggtaa
   112981 aaaaatcatt atttcaacca acttaacacc atctcaaata ggaaatactt acactcaaag
   113041 aactctctct agaatattag ataagtttag gattttagaa tttactggag atgatttgag
   113101 atgggaaaga tttaaataaa atagccctta aaaaacattt ttttattttt aaatagagag
   113161 gtaagagcaa acttgcttct ctgtttaaaa cttatatcac ataaattaaa acatactttt
   113221 tatttttcta tttacatatc taatgtatct taatctaaca aatcatttac attcttagta
   113281 gtctatattt attgatacta taaattaaat ttgctatatt acataatact atgctagaat
   113341 gattctaaat tttatattta aaactatcac attgcaagta attcaaaatt ttgttgtatg
   113401 tttaatttca tttttaatac aataaaaatg aaattaaaaa aagatactta aaagtatcct
   113461 gtaacataga aaattatatt aatttgaatt tatgtacttt gtggagctgg tgataggaat
   113521 cgaacctaca acctgctgat tacaagtcag ctgctctacc gttgagccac accagcatat
   113581 aatctagtat ttatctctaa ttcaaaattt ggtgggacta acagggctcg aacctgtgac
   113641 cccctgcttg taaggcaggt gctctcccag ctgagctata gtcccatact ggtgactcgt
   113701 aggggaattg aacccctgtt accgccgtga aagggcggtg tcttaacctc ttgaccaacg
   113761 agccatattt tggtgatcta tccgcgactc gaacgcggga caccctgatt aaaagtcagg
   113821 tgctctaccg actgagctaa tagaccacat tttttcgact tttttcgtcg tttctttcac
   113881 tcacaagtta tattatagcg tctatataat ttttagtcaa tagttttttt tacttttttt
   113941 agaatataat taaaatcatc tttagccatt tattttcaac aaaattcttt ttaaaaaacc
   114001 tatatgtatc tacataaatt caactttaat ttcagttaga atatgtataa gtagctttaa
   114061 cttaataaaa aatcaatgta agtcaaatat aaaagagcat ctctaataac tataaacatt
   114121 atcttgagat actcttcttc aactatttta aattatttaa ttgataaaat attaagcaaa
   114181 tatatttctt cttattatag tttgagctct atttggacca acagaaacca tatctacact
   114241 tactccaact agttcttcta tttttgctac atatttcttt gcattttctg gaaggtcatc
   114301 aaagttatct atttgagtta tatcttcatt ccatccatct aattcttcat atacaggttc
   114361 acattttgct aaatcatcta atgaagctgg gaaatccgtt attatcttat cgcccatttt
   114421 ataagacgta caaactttta tcttatcaaa tccagttaat acatcaagta acataaatga
   114481 aatactagtc aatccattaa ctctagctgc atacttaact ataactgcat caaaccaccc
   114541 acatcttctt ggtctaccag tagttacccc aaattcatgt ccttgttctc ttatcttatc
   114601 tccagtttca tttatttgct ctgtaacaaa cggtccttct ccaactcttg tagtatatgc
   114661 ttttactata ccaacaacgt cttttatcat atttggtcct atacctgcac caattgcaaa
   114721 tccaccagat gttggatgag aagatgtaac aaatggataa gttcctaaat ctaaatctaa
   114781 taaagtccct tgtgctcctt caaacaatac ttttttacct gctcttactg catcatatac
   114841 aataacagac gtatctgcca catactttct tatttgttct gcatatccta gatattcgtt
   114901 atatatagtt tcaaaatcaa ataattcttc ttttccatat atatttttaa ctatttcatt
   114961 tttagcatct atttgagctt ttaattttat agcaaattta tctttatcca ttaagtcaca
   115021 tattctaata ccagatctct ctgttttatc catataacaa ggtccaatac ctttttttgt
   115081 tgtacctatc tttaaatcgc ctctggcttc ttctgacaat gcatctagtt ctttatgata
   115141 tgggaatatg acatgtgctc tatcacttat ttttatattt tctgtactta tattatccgt
   115201 tttaaacatt tccaattctt ctaaaaatcc tttagggtca aacactattc catttccgat
   115261 tatattcact gtatttggat ttaaaactcc agatggaatt agatgtaatg cgtatttttt
   115321 accttctaca actaatgtat gtcctgcatt atttccacct tgccctctta ctactacatc
   115381 tgcttgagta gcaagataat ctataacttt acctttacct tcatctcccc attgagaacc
   115441 aacaattgca actgttttca tgtaattcac ctctatattt tatatactct cgaacacttt
   115501 acttacttat tctatcaaac attcgtattt ttttcaactt ttttagtatt ctccaatatt
   115561 taacatatat tcttctattt ttgaaaactc ttctttctct attatttctt tttcatattt
   115621 tataactttt tccataaatt tatccacatc taaaagtttt tctaatttac atatgttaat
   115681 tatgtttcca aagtttgtat tagtcatgtt tatatgatac tgattatcca cattattagc
   115741 ataaacaaca atagattctc ttaaattatt gtcaattact ctaaataagt ttatttcatc
   115801 aagtacttta attatattgg gatatatata ttttaagctt attttttcca tattattcct
   115861 cctaataatt aatatttata cacagataaa gcaagccaaa agcttgcttt atctacttat
   115921 tcacacttat caacaggctc tctgtggata gtgtggatag ttttttagct aaatttcaat
   115981 gtttggacat atttagtgac atgtatccac atttttcctg tagaaagaaa ggacgttctg
   116041 tggatattcg ttagattata ggtctctcaa cttatcccca aatctttgaa cttcaccaag
   116101 ccaaacaagt tccacagaac cagtttcacc gtgtctattt tttgctatta ttacttctcc
   116161 tatattttta ctctcagaat cagcatgata atattcgtcc ctgtataaga acataactat
   116221 atctgcatcc tgttctattg ctccagactc tcttaaatca gataacatag gtctatggtc
   116281 tgctctttgt tctggtgcac gtgataactg agatagtgct actacaggac agtttaattc
   116341 ttttgctaat atttttagtg accttgatat cttagatatc tcttgttgtc tgctttcatt
   116401 attaccttca ccttccataa gttgaagata atcaataagc actaaatcta gtcctttttc
   116461 tatttttaac tttctacact ttgaccttag ttctgatatt tttataccag gagtatcatc
   116521 tatgtgtatt ttggcatctg ataatactgc catagcatct ataattctag gccaatcatt
   116581 atcattaagt gttccagtct ttattttttt taattctaca ctagattgtg aagataacat
   116641 acgttgtact aattgttcct tagacatctc taaactaaat acagctacag aggcatcacc
   116701 ttttaaggct gcattttgaa ccaagtttaa agaaaaggca gttttaccca ttgctggtct
   116761 agctgcaatt aatattaaat cagtcctttg aagaccattt atttttttgt ttaaatcttt
   116821 aaaaccagta gttataccag tgacatcact cttgttagtg tataattttt ctatcatatc
   116881 ataggcatcc atcaaaacta agtttataga tttaaaatca tcactagttt tctcctgtga
   116941 tatatcaaat atactctttt cagcttgttc taaaacatct tcaatcttag ttgctccact
   117001 atatcctaga tttattattt cattagaagc ttttataagc tttctaagta cagacttttc
   117061 ttttactata tcagcatagt attttacatt tgaagtcgtc ggtactatag tagaaagact
   117121 tgtaatataa ctgattcctc caatatcatt aagatgccct tgttttctta gttcttctgt
   117181 taatgttatc aagtctatag gctcaccttt attacttaaa gttatcatac attcatatat
   117241 tattttgtga gcctctttat agaaatcatc aggctttata gtttctgtaa ccgttattat
   117301 agcatcttta tctagaagta tagaacccaa tattgattgt tctgattcta cactatgagg
   117361 aggaattctc gtcatatctt ccatcttaat cacctctagt tattactgtt tttcttttac
   117421 atccactctt attttagtag ttactttttg atgtattttt atttctacaa aagttgaacc
   117481 taaagatctt attggttcat ctaataatat ttttctttta tctacatcta tgtctttttg
   117541 tttctttaat tgctcagcaa tttctttaga agttattgaa ccaaataatc ttccaccttc
   117601 tcctgctttt gaatatattt ctatattaat ttcttccatt tgcttaccta ataaaactgc
   117661 ttcttcatac tctttttgtg cttttatttc tttagattta ttcttttcat ttaattcttt
   117721 tattgctaca ctatctgctt gcacagccat ctttttagga aataagaaat ttcttgcata
   117781 tccatcactt acttctttca tttctccctt tttaccagtt ccctttacgt cttttaataa
   117841 tataactttc atctattctt cctcctccaa atactcctct attattttat ttaccatctt
   117901 ataagcttct tttagagaaa cattttttaa ctgtgctcca gctatatcta tgtgtccccc
   117961 gcctcctaat ttttccataa gtacatgtac atttatttgt cctaaagacc tcgcacttat
   118021 aaatatagta tcatcttttt cacctaatac aaaggaagct tctacttctt tgatatttaa
   118081 taactcatca gcagtttgag ctattataac atttatacta tctatctcag tacttgaata
   118141 tgctaaacat attctattat taattatttt agtactttga attatttcag cttttattat
   118201 gaaatctttt acatcagaat tgaagaattt ctttacctct atagtatctg ctccaacttt
   118261 tctaaggtaa gaagcagctt caaaagttct aacacctgtt ttgaatgcaa agtttttagt
   118321 atctagactt atacctgcta aaagcccttc agctgtaagt ttatttattg ttacatcttc
   118381 atccatatac tgaactaact ctgtaaccat ttcacacgtt gaggatacat atatctcatg
   118441 gaataaaagc actgcatcat ttataaactc tacacctctt ctatgatggt ctataactac
   118501 taccttctct gatagcttta acagttcttc acattcagta taatttggtc tatgagtatc
   118561 aactactaca actaatgtat ttttagtgca gttgtcaata gcttcctctt ttccaataaa
   118621 caacttttta tagtaattat tttcatttat tttatttata aatatttcta tagattcatt
   118681 tacagattgt aaaactatgt ttgcagtttt gttacaggat ttacatatat cataaacacc
   118741 aactgctgct cccatagcat ccatatcagg atatttatgt cccattatat aaacctggtc
   118801 actttgttgt ataacctctc ttaaagcatg acctattaat ctggatttta ctttggtttt
   118861 cttttctaca gctttagatt ttcctccata aaacacaaat ttatcttttg tttttacaac
   118921 agcctggtca ccacctctac caagtgctaa atcgagagca cccgtagcaa gttttaggtt
   118981 ctcatttaat gtatctccat ctataccaat tcctatactt atagtaacag gaagattatt
   119041 tccataatca atatgtctta ttgtatctaa aatagaaaac ttctcagctt ccaatttttt
   119101 taactctttt ttatgcatta ccaagaagaa tttgtctttt gaagttcttc tcaatgcacc
   119161 atttgaattt aattctaaag cagaaagtat tttctctact tcaacattaa ttaaagctct
   119221 cttatcttct gctgcacttt ttaatacttc atcatatcca tctacttgta ttagcatcat
   119281 tgcatttttt tcatcatcat aattttgttt tacttttaaa tattcagtct tgtctatcca
   119341 gtataatatc atcaaatatt taggattttt ttcttgatca ttttttataa cattataaat
   119401 tattgtatat tctttttctt tatagtttat ttctgtgtac atctctttat tttcatttaa
   119461 tacttttctt aaattaagat ttttaactat atcctctata tttttatcaa gtaaatcttt
   119521 ttgaccaatc atatcataaa actttccatt ataccaggat atatttccat caaattctaa
   119581 aatacataat ggtattggaa gatttattat ggctttttta gttgtttcat ctatatctaa
   119641 agataaattt tgaatatact ctgtccattc atgacgtcta atattagtag ttctccaatt
   119701 gtgaaaaacc atatatacaa aaatacagaa aaataaacac cctacataca agttgtaata
   119761 aagcaaaatt atactagaaa taccaataac aattatatat aaatttattt ctggcatatt
   119821 taatttaaag gcttgtttat tactcatttc tatcctccta agtggattta tagcttctta
   119881 cctttctaaa gtcaattata ctatctacca taccaacaaa agatattccc ataaatccaa
   119941 ataaacataa aattatccct gaaaaaaaca taattttatt tggtccctgt cttatccatt
   120001 tctttaagaa ataaatgcaa actgctatac cttgaattac aaacattaaa ttaaaaacta
   120061 gctgtaaatt agtcattatt aattctgtat ataattttga accaataatt tgaataaata
   120121 agactaataa ataaagtaag aaagttgtga gtatagcatt tcccggtaaa taaaaatcag
   120181 caaacttagg aaatcttata ttcatctttg taatcctttt tataaaaaat acactcaaat
   120241 aatatgtgac aaacgctgat aacaaccctt gtaaaaataa catcattggt agcatatttg
   120301 taaaataact tacaatctca tctggcttca ttttatcaaa cactttaagt tcagttgcag
   120361 aaaaactatt tttttgaata tttacaattt ctgatatcat cttagaaact tcatctaata
   120421 gattcacatt taaaaatgtc tttaatacaa aaaaatatac aagcattgaa agtacaaata
   120481 ttatggttcc accatatatc ggttcgaatt tattactgtc ctcttgttca aagcttctct
   120541 ttagcatctt tcctattact atacctggta aagaatacat tatacatata tttaatgcat
   120601 aagaaatgtc tgcaaataga atcagtacac aaaatgtaac caaaatagat ataagagaat
   120661 actttctatc agtaatagca cctataatta catatggaac agctgctaac atactaaata
   120721 ttcctagcat tggaatatag gctattacta aagcgattat tatagctaaa actattatag
   120781 acattgcctt agatagtcta attttattat tcaatttaat atcactccct attatccata
   120841 tgttttttta aattagataa atctccatac catctttcaa cgctatggtc ctcatctata
   120901 ccaattttta ttttttcctt gactttataa tccacatctc taaaactaat tcctaatctc
   120961 tttgctaaga gatatgttat cattattata tttgctaaag tatcttgaat tgcttcatct
   121021 aatggtttta cccctttaaa caataaatta aacaaatcac ttacactcat taatatttct
   121081 gttttcatcc attctattat ctttatgttt ctcgttatct cagaaccttt atctattttc
   121141 acgtttacaa ccctccttaa tatataatat tatatcataa ataataatat atttaagtat
   121201 ataaacaaaa aaacgagctt tatagctcgc ctcatttaga tatataaata catataataa
   121261 aaaatgagca caaggctcat ttttttagtc taatgtatat ggtaaaagtg ctatatttct
   121321 cgctcttttt atagcaactg ttaattctct ttgatgctta gcacaagttc cagatattct
   121381 tcttggtaat atctttcctc tttcagttat atacttttgt aatctttgag tacttttgta
   121441 atctatttta gcgtttttgt cagcacaaaa ttgacaaact ctttttttct tacgtctttt
   121501 tttattcatc atgacttttt tccctccttt ttaaaatggt atatcgtcat catctatagc
   121561 ttggaaacct tgtgggtcta aaccttgagg ttcaaagctt ggctcaaaag ctggagcact
   121621 ctctctatat gaattttccg atttattctt actatccaaa gcttgtactg atctagtact
   121681 tacttttgta aaagttctct tttcacctga ttgtgtctga taattgtcta ctcttataga
   121741 tccttgaagt gctactaatc tacctttagt tatgtagtta gcacaaaatt cagcagattt
   121801 acccattact tcaacaggta taaaatcagt ttctttagat ccatcttttt ttacatagtc
   121861 tctatcaatg gctattgtaa aggatgccac tggtgttcct gtacctggga tgtatcttaa
   121921 ttcagggtct ctagtcaacc ttcccactaa tacaacttga ttcataaaaa caccacctat
   121981 tttttataat aaaaccagtt attaagcaac aactatcatg tgtcttatta cgttttcatt
   122041 tatctttaag tttctgtcta tctctttagg aacgtctact gctgatttga agttaactaa
   122101 tacatagaaa ccttctgtaa acttagctat tggataagct aattttttag ttccccaagt
   122161 atcaacttta actatttctc cgtcagttgc aacaacttcc ttaactttgt ttagtatagc
   122221 ctctcttact tcttcatcag agtttggctt taccacataa actaattcat aatttctcac
   122281 tataattcac ctccctttgg acttaacggc tctacactct tagagcagag aaatgagact
   122341 aaaatctcat acctacacat tttatcattt attcttattt ctgtcaattt aaattttgga
   122401 caaagtttag tataaggtga attatatact tttcaaacaa acaagggatg gcaacaacca
   122461 tcccttgtat tatatataag ttattatttt taattaagct tctacaccca tagcttcttt
   122521 taatacagct gctatatttt ttataccttc tattattttt tcttctggca tatttgaata
   122581 gttaagtctg aaagtatttt ctctaccacc attagggaag aatcctcctc cagcaacata
   122641 agcaacattc ttatctaaac attttggcat taattcttta gcatttaaat tacttggaag
   122701 ctctacccat gtaaataatc caccttctgg atgagtaaat actaatcctt ctgggaactc
   122761 ttcttccata gtcttaagca ttacatctct acgtttaaca taaactgctt ttattttgtc
   122821 aacatgtgca tctaggtcat acatatccat aaatttgctt acttccattt gagatatagt
   122881 tgatgcttgt aagtctgcac cttgttttgc aaagttaaac ttagataaaa tttctggaga
   122941 agcacaagtc catcctaatc tgtatcctgg gcagaatatt ttagagaaag ttcctaagaa
   123001 tattactaat ccttttgtat ccattgattt taaagatggt aaagtctctc cttcaaatct
   123061 taaatctcca tatggattat cttctattac tggtatttca aatttattta ctatttccat
   123121 gaatttttta cgtctttcaa gtggccaagt tcttcctgtt ggattttgga agtcaggtat
   123181 tacgtaaatc atttttattc tatcagttgt ttctagtatc ttttctaatt cttccattat
   123241 cattccatca gaatctgttg gaacatctat gaatttaggt tgataagatt taaatgcgtt
   123301 tatagctcct atgtaagatg gactttcaca taaaattaca tcaccctcat caatgaatac
   123361 ttttcctgca aaatctagac cttgttgaga accacttgta actaatatat catctttgtt
   123421 tacattagtt ttgtttttat cattcattct agctgctatt ttttctctta atggttcata
   123481 tccttctgtt gtagtatatt gcatagctga tcttccattt tcttcaagca ctgcaactga
   123541 tacttttttc atttcctcaa ctggaaataa ctctggagcc ggcattccac cagcaaaaga
   123601 tattatttgt ggttgttgag taagttttaa aagctcacgt atttctgatc cttgtaatcc
   123661 ttgcattctt tttgcatatt taactgccat aattaaagca cccccatgaa aatgttttct
   123721 tcaattctta ttataccaaa attttggata ttaatatacg gtatttgaca ttttttaagt
   123781 gttaaatttt tatcactttt ttattagctt ttttactctc ttttctaagg tctctctatc
   123841 aagcattatt agccttgaac atttagtaca ttttatcttt atatccattc ccgttcttat
   123901 gatttcaaac tctttacacc cacatgcatg ttgctttttt aattcaacaa tatcacctat
   123961 ttttaaatcc attggcataa ataattagcc tcctaatcta acttctctac ttcttttgaa
   124021 ccattttcta atttacttat acaataaatt ccttttatat ctacattatt ttcaaccaaa
   124081 atagttttta tcttttccat atcttcaaaa gaaaatttaa ttgatattcc acaacttgct
   124141 gttatttctc ttggtgttgg aagagccatt acttttagac tattttcacc aaataacttt
   124201 tctgatctta tcgcatgatg tgtcgaatta aatgacacta tatacatttg attcattact
   124261 taatcctttc tgactatcta tttgagttaa tctttattgt tagttttata ttattaaaca
   124321 tacatacatt atatagaaat ggtatttgat gcattcttta atgtctcaac tatagtatac
   124381 atatttgtaa ctgtacctac ttgtaatttg tcttttaaat tataataatc taaacaagta
   124441 ccacaagata aaacttctac acccatattc tcaagtattt ttagattttc tatggtttct
   124501 tcattttcag cacttaattt tactcctcca ttaactaaaa gtacatactt aggataaggt
   124561 ttagattctg ttaatgtata tataaatcct tttattaaca cttttcctaa ttcgtcattt
   124621 ccaagtccca tcttatctga agatataaat atacatgtat tgtttaattc actttcttta
   124681 ttatctacaa cattttgttt atctagtata tttttacctt ttctaatttc tatagatata
   124741 aaattctctt tttcgtcaac aatatttgct tcacaactta aagatttagc aagttttaat
   124801 atattctcct tagctgtttc attatcaact attgtaacta caacaccttc ttctaggtta
   124861 tccaattctc tttttgtatt tataactggt ttaggacaag caagccctct cgcatctatt
   124921 tttatactca ttgtctgatt catctcctta aaaatattca tacaatttat attttatcat
   124981 agatattatc ttgcttgtta tagattgttt ctataccctt ataggtttat ttaccctaca
   125041 ttatttctaa gtttttgtac ataaatacac ctttttgata atattctaac tctttttctt
   125101 ttgatatatt tgaatataat tgacctaagt ctatatataa attggccaat attctattgt
   125161 tgcctaaatc tgatactatt tttatgcatt taatcagata ttcaattgca agagttactt
   125221 cattctgatt tttatacata ttagcataga atctcaatgc tttatattca ttgaatttat
   125281 ttttattttt tattgatgaa gctaaggcta tcttacaata ttttctagct aaatcataat
   125341 cttctttatc tatatatgct tctattatct taaataatcc tgacatcatg tattcatctt
   125401 catcattttt ctttatgtca tatacctttt gtgaatattc aagtactcta tctgtttcac
   125461 ctatttttct gtaaacatca caaattgtta aatacacatt tgctaatcca gttttattat
   125521 cctcactctc aagtattttt agtgcttttt taaagtaatc tcttgattct tcatattttc
   125581 caatctcaag catattattt gcttttaaca ccaaaatatc gacatcttct tttctatcat
   125641 ttctattatc tatttcattt atcttttcta tgtacttcaa tgacatattt ggattatcta
   125701 gttttatgta acaatatgcc atcttactat atagttcctt gtgtatgtta acatcctcaa
   125761 atttactctc tgacaaaatt tcctctgcaa aattaaagtg gcttatagca cctttataaa
   125821 agtcttcctg catatatatt ttccctatgt ttaaataaca cttaagtata ttttcactat
   125881 cactattttt tataaagaag tacaatgcct tttcaaagtt ttctatagca tcattataat
   125941 tagatttttt caaattaata ttagccatta aaaaattaca tctgccatag ttctccatta
   126001 aatcgtatct cttacatata tctaaaactt cttttatttg gtcctcagcc ttgtttaatt
   126061 cattttcttt tatataaatt tcgctctgta gtattaaatt atcagttatc ttttttgatt
   126121 gcatttcctt ggtctctaat aagtattcta cacttacatc tagcttatcg cctagatatt
   126181 ccaacagttc ataactagta tgagatttat ccctctctat atggcttatt tgtgctgctg
   126241 ttatcctatc tccagctaat tcttttaatg tcatgttttt ttcttttctt aattttttaa
   126301 tcttttctcc taagctcaaa atttccatac tattcccacc ttttgaagac atttttttat
   126361 aatataatta taacttatat ttattttaaa aacactactt ttattttaca atattttcac
   126421 tgtacattaa atgatttccc ataaaaatga ctaaaattta gtttattttg agttttatta
   126481 atttaaataa atcatttttt aaatttgtta ctattttgta ttcatatatt tgctcataac
   126541 gactataatt atatataaga atagttttta agagaggaga aatttttatg aaaaataaga
   126601 aaataatgtt agtgttaagt atattatcta tatctatatt cgcagttggt tgtactaatg
   126661 ctcaaaatgg aagtgattca tctaaaaaag aaactaagag caatacaaat gttgagcaac
   126721 caaaagaaga aaacaatact gaaaaagagg ttcctaataa caaagctaaa cctactccaa
   126781 aagaagaaac taaaactcaa tcagctacta tttactcttt tgatgtagat aagacagatt
   126841 taattgaaaa taaagttgat ttaaataaaa ttgatgagaa cactttattt gaagaacttc
   126901 aaaaacttaa agttgttcca gaatctgcaa aattaaattc atttactaca aaagacattg
   126961 atggtgtaaa aactggtata ttagatgtta gctctgactt tacaaagtca aacttaggta
   127021 gtgatgcaga aactttaatg cttgattcag ttgctcgtac ttacataaaa aatatgaatg
   127081 ttgaacaaat aaaaattact gttgatggtt ctaattacga aagtggtcat atagttcttg
   127141 aagaaggaga ttacttaaag taacttctta aaacaattat caaatagatt agaggttctt
   127201 agggacccct tttctttttt atacaaaaaa ggagatgatt caaattttta ttttgaaata
   127261 tccccttttt tatttctata ttattaaatc tcatgctatt tattttttga aatttttttc
   127321 aaagcttcca ctgctttatc tatctcatct tttgtgttga aatatcctat actgaacctt
   127381 actgcacctt gttttaaagt acctaaagtg gtatgtgcta gtggtgaaca atgtattcct
   127441 gatctagtcg ctatattata atcactatct aataagaaag taacctctcc agaatccata
   127501 tctcctatat ttagagctat tactgatgct ctttttttac tgtcctttgg tccatatatc
   127561 tttatatctg gtacttcctc taatttgtct atcatatatt gacataattc ttcttcatgt
   127621 tgtcttatat tgttgattcc tctttcaaat ataaatagta taccttggtt aagacctgct
   127681 atacctggag tattatgagt tcctgattca tatttatctg ggaataactc tggttgaact
   127741 atttcttctg atttactacc tgttccacct tcttttaata tatttaagtt caacccttct
   127801 cttacatata atatacctgt tccttgaggt ccaaataagc atttatgacc tggcattgcc
   127861 aacatatcta tattacattc atttacgtct atatcataaa cacctgctgt ttgtgatgca
   127921 tctactaaaa atagtatatt atgtttttta gctatttctc caactttttt tatatctatt
   127981 aaagttccac atacattaga cgcatgtgtt gttacaatca atttagtatt attctttatt
   128041 gatttttcta aatcttcata atctaaaaat ccctcataat cgcattttac tacagtattt
   128101 tcaatacccc ttttttccaa tgcttttata ggtcttatta ctgaattatg ctccatagac
   128161 gttgttatta catggtctcc ttcttgtaat acacctttta tcgctaaatt taaagaatct
   128221 gttgcattag atgtaaatac tatattcata ggattaatta cattgaacaa cttagctata
   128281 ttctctcttg tatcatatat ctccctagca gctctcatag caagtttatg gcctgctcta
   128341 cctggatttg cacaataatt tttcatacaa tctaaaacag cattatacac tctttctggt
   128401 tttggatatg tagttgcagc attatctaaa taaatcataa caatcttcct ctctgtttta
   128461 tatttttgtt ctattcaaga agcattgata caatactatt taaatcatca tcattatagt
   128521 attctatctc tattttacct tttttctttc ctttagaaat attcaccttt gttccaaata
   128581 tatttctaag tttatcttca acatctaaaa taaatacatc cttaggttta gattttttag
   128641 gttcttcttg tttattttca gatatttttt tagctatatt ttcgacttct cttacagaaa
   128701 gttcttcttc ttctattttt ttcgctattt gaagttgcaa atctttatct gcaattctca
   128761 ataaagcctt accatggcct gctgtaattc taccactgtc tatcatttct ataacatctt
   128821 gtccaagatt taaaagtctt agtgtattag ttatatgagg tctactcttc ccaacagctt
   128881 ctgatatttc ttcctgagtt acattgtaat gctctattaa actcttatat gctagagcct
   128941 cttctattga atttaaatct tccctctgta agttttcaat taaggctatc tccattatat
   129001 ctttcatatc tatatcttta attatagcag gtatttgatt tttatttgca agttttgatg
   129061 ctctaaatct tctttctcca gctattatca tatatttatt attttcatcc attttaacca
   129121 ctattggttg taaaacacca taatttttta tagaatccga caatactttt atcttttctt
   129181 catcaaattg ctttctaggt tgaacttcgt ttggatatat tttgtctata tctatgttga
   129241 ctatttcttt ttctgaagtt tctcctttaa tttctggtat caatgcacta agacctctac
   129301 ctaatctatt acttctttta gacttattct ccatactacc attcctcctc ttctaaatct
   129361 ataaattctt ctgctagctc caaataagct acagaccctc tacatctttt atcataataa
   129421 attacaggtt ttccatgact tggagcttct gcaagtctta catttcttgg aattaaagtt
   129481 gtatatacac tacctttaaa gtatttctta acttcttcaa ctacttgtat tgataaatta
   129541 gctcttccat caaacatact taaaacaaca ccttgaattt ctatatcagc atttaatctt
   129601 gattttacta attttatagt ctccattaat tgactaacac cttctaaagc ataatattca
   129661 cattgtattg gaattaaaac actatctaca gcagttaaac aatttattgt aagcatcccc
   129721 agtgagggtg gacaatctaa aaatatataa tcatattcat ctattaccgc ttttatggaa
   129781 ttttttaaaa tatactctct attagtttta gatgtaagct ctatttctgc acctgatagt
   129841 tcagtagctg atggaactac atctacattc tcaaattcag tacttattat tgcttcttta
   129901 atatgtaacc catctaacat aatttcatag attgtatttt ctacttcgtt tttattaata
   129961 ccatatccac tagttgtatt tccttgtggg tctaaatcta atactaatat tttctttccc
   130021 aaagttccta agctagcact taaatttaca tttgttgtag ttttcccgac tccacccttt
   130081 tgattgaata cagctataac tttgcccatg atgttccccc ctttaagaat taaattaatt
   130141 ttaaatgttg aataggtgtt ttttaagtat aaataatgtc tataaatcaa tttatattac
   130201 aaggcttata ttacaaaaaa agattactgg taagcagtaa tctctatttt ttagggattt
   130261 ttacaacaac ttccatataa tctcccttat ctatttcatt atacttagca tcaattcctg
   130321 tatttgatat agcatcaaag gcctgcttta tagtatttat gtaaattctt atactcatag
   130381 caccctttat attctgtttt ttatcaggct cttcttgaac tttagtttct tctaatacat
   130441 cttgtatcaa tttttctgtt tttttaacag tcaattcatt ttttatgact ttgtctaaca
   130501 cactttgcat taaatcttca cttggtagtt taagaaatgc tctagcatgt ctttctgtta
   130561 aattattctc tattagcttc atttttatat cgtttggaag ctttaatatt ctaagcttat
   130621 ttgctacagt agattgattt ttgcccaatt tttctgctaa ttgctgttga gtaaaagcat
   130681 gttcttttat taagttttca taaccaattg cttcttcaat gaaatttaag tcttctcgtt
   130741 gcaaattttc taataacgct agaacagcag aagattcatc gttcatatta tttataattg
   130801 ctggtatggt tttaagctct gctaatttag ctgctcttaa tcttctttct cctgcaatta
   130861 gttcatattt gccatctttt gctctaactg ttataggttg aattatacca tataccttta
   130921 tagaattgct caattcctcc aatgaaactt gtgaaaatat ttttcttggt tgatatggat
   130981 ttggaactac atcttctata ggtatctcca taactctttt atcttccata acatacctct
   131041 cttattttag atataaatta tttttgttct ctatatgtac atacaaattt atttctgcat
   131101 ctactttaat aattccttta tttttgtttt tttacagtaa gcttaattat ttcctgagaa
   131161 ataattaagc ttaccaataa taaatttttc attacttaat aggatttttg gctggtttac
   131221 cagcttttct agggtactta actggtgttt ccatcacttt tttaaaaact aatatattat
   131281 gatttaaatc tacctctggt aactctacat ctattttttc aatatactcc aatcctaaaa
   131341 catcaatagc cttttgtgat tcttctagct ctaaattagc attcggacct tttaagcaaa
   131401 taaaataccc tccaactttt acaaatggta cacaaaattc cataagaatc ggtaatccag
   131461 caacagctct tgccgtagca acatcatatt tttccctata gtcttcattt ttaccaaaat
   131521 cttcagctct tccatgtata aatgtaatat tatctaactc tagtactcta ctaacttcct
   131581 ctaaaaagtt tattctttta tttaacgaat ctaacaaagt aagttctaag ctatctaaac
   131641 atattttcaa tggtattcca ggaaaaccag cacctgtacc aacatctatt atagacatcc
   131701 cattttttat atatccattt tttacagctg aaatagagtc taaaaaatgt tttatataca
   131761 cttctttttc atcttctatt ccagtaagat tcatcttttt attccattca actaatatct
   131821 ctctatagat tttaaatttt tctaacatac tgtcattcgt atctatatta aaaccttcaa
   131881 tcccgttttt cagaagttct atattattca cctttgccac ctctagttct tctgatttgt
   131941 tctaggtata taagtaaaac tgatatatca gctggagaaa caccagatat acgagatgct
   132001 tgccctattg aaataggttt tatatcatct aatttctgtc tagcttctaa tctaagacct
   132061 tctatagatg aataatttat tttctcatcc agctttttat tctcaagttt tttaaattgg
   132121 tctatttgtt tcaattgttt ctctatataa ccttcatatt tagttattat tacacactgt
   132181 tctttaactt ctcttgaaac atcttctcca gcgcctttcc ctaattcttc aagcaattcg
   132241 taagtaacct ctggtctctt taaaaattca tatagagata ttccaacctt tattggtgtt
   132301 gctccttttt cttctaacaa actatttact tcttttggtg taactctttc attttttagt
   132361 ctttcaaatt ctttctctac agcagccttt ttatttagga acctttcata tctatctttt
   132421 ttaactaatc ctatatcata acctttttga gttaatctca tatctgcatt atcttgtctt
   132481 aaatatagtc gatattctgc tcttgatgtc atcattctgt aaggctcgtt agttccttta
   132541 gtaacaaggt catctaataa gacacctata taagcttctg aacggtctaa tacaaatggc
   132601 tcttttcctt ctatctttct aactgcattt ataccagcca taagcccttg agctgctgct
   132661 tcctcgtatc cagaagttcc attaaattgc cctgcactaa ataagttctc aacacccttt
   132721 atttccaaac ttatttttag ttgagttggg tcaacacaat catattcaat agcatatgca
   132781 ggtctcatta tcttacaatt ttcaagtccc tttatagttt tgtacatatc taattgaact
   132841 tcaaaaggta aactagttga aattccttgt atatacattt ctttagtatt taacccttct
   132901 ggttctataa ataattgatg tgatgtttta tcactaaatc gtactacttt atcttctata
   132961 gaaggacagt atcttggacc agtactttct attactccac tatacatagc agaccttttt
   133021 aaattatcca gtataacttt ttgagtttct tctgtagttc ttgttaaata acaaggttct
   133081 tgtttttttt ctatattttc attcataaat gagaatggag ttactttttc atcaccctct
   133141 tgtaaagaca ttacagagaa gtctatacta tctctatgaa ctcttgctgg agttcccgtc
   133201 ttaaatcttc tcattctaag accaagctca actaagctat ctgtaagata ttttgcatac
   133261 cccaatgcat taggaccttc ataaaatgca acttcaccca tatatatctt tgagttcaga
   133321 taaactccag tggccaatat tacagcttta gatttaaatg aacatcctag tttagttcca
   133381 actcctatta caacatttcc ttcatgaagt atttctacaa cttcatccat agctatatca
   133441 agatttggtt catcttctaa tgtctttttc atttcttcat gatatttaaa tttatctgct
   133501 tgtgctctta aagagtgtac cgctggacct ttggcagtat ttaacattct actttgtata
   133561 tatgtcttgt ctatatttaa tcccatctga ccgcctaagg catctatttc tttaactaat
   133621 tgacctttac cagtccctcc aattgatgga ttacaaggca ttaatgctat ggaatccaaa
   133681 gacattgtta ttatcaaagt tttatatccc attcttgcag tagccaaagc agcttcacat
   133741 ccagcatgtc ctgctccgac tactataaca tcatattttc ctgcttcaaa ctttatcatt
   133801 tataattcct ttcttttcaa aattaatgtt tcatgagaaa cacttcaaat tttttaaaaa
   133861 tctctataat aaaaacaagt ttacttttgt acattactta ccaatacaga aattatggaa
   133921 tatattatct agtaaatcct ctgttactgt atcaccatta atatatccaa gatagtccca
   133981 tatatttttt aaatcgactt ctacaaagtc aaatggcata ctttgttcca aagcaattaa
   134041 agcatctgtt gcagatttat atgctttact aagtgcatct ttatgtcttg aatttgttac
   134101 tactaaacta gaattatttt tgatactacc tttatatacc atagactcta ttttatcttg
   134161 caattcttct attccttctt gttgtaaagc tgatattttt attatactat tattttctac
   134221 atatttaagt attttttctt cttcaatctc ttgtttcaaa tcattcttat ttaacagcac
   134281 tattgtttgt ttatccttaa gtttttctaa tatctctata tcttcttctg acaactttct
   134341 agatgcatct aaaaccatta ctatcaaatc tgcactagta aatgattctt tagacttttc
   134401 aacacctatt ttttcaacaa tatcatcagt atctcttata cctgctgtgt caacaatttt
   134461 taaaggtata ccttttatgt ttacaaactc ttctataaca tctctagtag ttcctggtat
   134521 atcagtaact attgctctat tctctcctaa aatagaatta agtagtgaag atttacctac
   134581 atttggtttc ccaacaatta ccgtctttaa gccttctcta agtatttttc cactttcagc
   134641 tgtatcatat aattttttaa tgtctttttt aagttcatca gttttttctt taagagtttg
   134701 atatgttata tgctcaatat cttcctcagg ataatctata gcaacttcta catgagctaa
   134761 tatctcagtg actttatctc tcaattctct tatcttcttt gataaagaac cctctaattg
   134821 attttgagca acttcatgag ctatatcagt tttggctttt ataacatcaa ttacagcctc
   134881 tgcttgagat aaatctattc ttccatttaa gaatgctctt ttagtaaact caccagcctc
   134941 tgctaatcta acatcttttg atagtattaa ttctaatatc ttctttaccg aaataaatcc
   135001 accatggcaa ttaatttcta taacatcttc tcctgtatag gaatttggtc ctttcatata
   135061 tgccaataaa acttcatcaa ttatattttc attatccact atatttccat atattaatgt
   135121 tctcttattg tattcttcaa tactctttcc agacatagat ttaaagattt cttctgcaac
   135181 cttcaaagct ttttctccac ttattctaag tatacctata ccaccttctc caggtgctgt
   135241 agctattgct gcaattgtat catctataaa caaatttatc acctcttaat tcataatttt
   135301 ttacatatag atttacattt aaccaatcat taatgattta ataatattaa aaaataaaac
   135361 cccctaatgt ttaggaggtt gactttatct tttacactca attactaatc ttctatatgg
   135421 atcggttcct tcactatatg taattacata tttgtcattt tgaagagctg aatgtattat
   135481 tcttctctca tatggattca tataatctaa ttttttagtt tttcttgttt tcgctacttc
   135541 tctagcaact ttattagcat atcttattaa agattcttct cgttttgatc tataattttc
   135601 tatatctaca agtactcttg tatgagaatc tttatttatt ttattaagag ctaatccagt
   135661 caaaaattga atagaatcta aagtttcccc tcttctacca attaaacttg cagcttcttt
   135721 gccttcaata tcaaccatga ttaaattatc tttttgagat acattgactt tggcatcaac
   135781 atttgcattt ttcaacatta cctctataaa atttttagct acatctactt ccctctcgat
   135841 aacaaaaatt tcataagtac catctttagc acctataaaa cctaaaaacc ctttacttgg
   135901 attttcaagt atttctactt ctatatcctc tgcttttaaa ttcaactctg ctatagcttt
   135961 acttatagct tcctctttac tcttactttt tattaatttt aggctttttc tcattaactt
   136021 tttcctcctt agagttagca gccagtttag cttttaaagg attcattatt aagtaatatt
   136081 gagctattga gaataagtta cttactgtcc agtacaatgt aagtcctgct gggaatataa
   136141 atccccaata gaaagacata cctgccatta catatgtcat tactttcata gagccttgta
   136201 actgatcttt tggtgtcatt actttttgca tgacatatgc acttgctcct gaaaatactg
   136261 ctaatacata atctggtgat gttaagcttt ttatccataa aaacccattg tcagctgcta
   136321 aaaatgcagc tttgtttgca aaaacgccat gagcaactgg ttctctcaaa acgctaaata
   136381 atcctattaa tataggaaac tgtattaata aaggtaaaca accagatagt ggattaattt
   136441 tagcttctcc atataactta acaatttctt cattttgttt ttctggctta tttttatatt
   136501 tttcttgtat ctcttttata cgaggttgta tatcttgcat tgcctttgtt gacttagtct
   136561 gcttaattgt taatggtaat aaaataatct ttacaagtat cgtaaaaagt attatagaaa
   136621 taccataatg attaacaaat tcaaatatta ccttaagaat caatcctaag aaatttccta
   136681 ttatattcaa tttttttata cctcctaata gttactctct tttattttag agggtcgtaa
   136741 cctcctggat gaaaaggatg acattttaaa agtcttctta tcgttaaata catacctttt
   136801 acaaatccat atttcttaaa cgcctctatt gaatattgtg agcaagttgg ataaaatcta
   136861 caggtaggtc cctttaaggg agatatatac ttttgataaa atctcactaa ataaatacat
   136921 aaattcgata aatacttact tatttccttt aatatataaa ttattttatt caaagtcatt
   136981 aacctccata tttatagcat acaattaaat agaaatatcc gttcttttaa ctaaattttt
   137041 tatagacttg tctatgtctt taaaagtagc atccttacta gatacccttg ctataaatac
   137101 tatatcatat ccaggcttaa ttttttcatc aatatttaat ctgtaggctt cttttattaa
   137161 tcttcttact ctattcctag taatagcttt tcctactttt tttgaaacag aaatacctac
   137221 tctactataa tctgatttat ttttaagtat atatattact aaatatttgt ttgcaaaaga
   137281 tttgccgtgt ttatatactt ttctaaaatc agagtctttt ttcaaccctt tagtcctatt
   137341 aaagtccata gttaacctcc ataaacacag ctatgaattg taattattta cacaaaaagg
   137401 ccacctttgc agcggccctt ttgtaattaa tgagttaatc tatttcttcc tttagctctt
   137461 cttctcttta acacgtttct tccgttagac gtcttcattc tttttctgaa accatgttct
   137521 ttacttcttt gtctcttttt tggttgataa gttcttttac tcattatttt gcaccgcctt
   137581 tcagatttta ttttccgttt ataaaaataa taactttacc ctcaaagtaa acataacaca
   137641 tataattata aatactttta ctactgttgt caacgagttt ttgggacgct tatatcacaa
   137701 aatctaccat atatatatta tgtatttttt ttattgaaaa tactagtaaa aatctattta
   137761 attttattct aaattatttt tttcaattat atacacaaat aaagtaattt taacatgttt
   137821 atatttttat caacaattag ttaatattgt ggataaatta gttacaaatc attgaagttt
   137881 gacatatatt ttgatattat aaatatactt gttgataatg tgcataaatg ttatcaactt
   137941 attagaaatt attcacagct tgtggatact tttgtgtata acttttaaga ttactgacaa
   138001 tactctagtt ataatcacca tttattgtat gtttatgtta tttataactt tatctacata
   138061 ttgtttatat cttttcatat ttttttaata atttatacta ttattaattt atcaacacca
   138121 ttatccataa atttagttat tctgtaaaat ttatatatat ttttgctttt ctgttaataa
   138181 ctttgtggaa aatattaatt attctgttcg gaggtttata ttatggatat agtttcttta
   138241 tgggacaaaa ccctacaatt aataaaaggt gacttaactt cagtaagttt taataccttt
   138301 tttaaaaaca tcgtaccatt aaaaatacat cttaatgatt taatcttact ggctcctagt
   138361 gattttaata aagatatctt agagaataga tatttacatt taattgaaga tgctattagt
   138421 caactgtcat taaaaaaata taatattaaa tttgtattga gcgaaaaaga ggttgctgat
   138481 ttaaattctg atagcacaga tttaaattat agagttcttt accccaatct aaatccaaaa
   138541 tacacatttg atacattcgt tattggtaat agcaatagat ttgcacatgc tgcatgcgtt
   138601 gcagttgcag aatctccagc taaagcttat aacccacttt ttttgtatgg aggagttgga
   138661 ttaggtaaga ctcacctaat gcatgctata ggtcatcata ttgttagtca aaaaaaagac
   138721 tcaaaagtag tttacgtttc ttcagaaaaa tttactaatg aacttataaa ctctataaaa
   138781 gacgataaaa acgaagaatt taggaataaa tatagaaacg tagatgtatt actaatcgac
   138841 gatattcaat ttatagcagg aaaagaaaga actcaagaag agtttttcca tacattcaat
   138901 actcttcatg aagcaaacaa acaaataatt atatctagtg atagaccgcc aaaagacata
   138961 cctacactag aagataggct aagatcgaga tttgaaatgg gacttataac tgatattcaa
   139021 gcacctgact ttgagacaag aattgctata cttagaaaaa aggctcaact agaacgtata
   139081 gatgtgccaa atgaggttat gtcatatata gcaaaaaata ttaagtcaaa cataagggaa
   139141 ctagaaggtg cattaactag agtggttgct tattcttctc ttagcaatag ggtaatatct
   139201 tttgatcttg ctacagaagc tttaaaagat attataacaa cttctaaaaa tgaagaaata
   139261 aatgttctca gaataaaaga aaaagtatct tctgtattca atttaaagat ggaagatttt
   139321 aattctaaaa aaagaacacg ttcaatagct tatccaagac agatagctat gtatttaacg
   139381 cgcgagctta ctgatttatc ccttcctaaa ataggtgaag agtttggggg tagagaccat
   139441 acaacagtaa ttcatgctca tgacaaagta tctaaggata tagaagaaag tgaagaaatt
   139501 aagactaaaa tagacaaaat tatatcagat ttgaagggat aatttataca caattgtatg
   139561 tttatatctc ttgaataacc tgttaatact ttttttgaac aaaaattatt aacaaattat
   139621 caagtctaaa ataacaaaga tattaacatc ttatacacat gttaatatct ttgtatttat
   139681 aatgttatac atacttatta acattatcaa caacacctac tactattact actatgattt
   139741 taacttattt ttatatataa aaagccagag gaggttatcc acattgaaaa taatttgtaa
   139801 tcaaaaaatc ctagcaaata gaattggaat tgctcaaaaa gctattaatg gaaaaacaac
   139861 aatagaatta ttaaaaggta tacttatatc tacagaagaa ggtcaattaa aacttactgg
   139921 atatgatgct gaaataggaa tagaaactta tgtacaagca gaaatcatag aaaaaggtga
   139981 tgttgttgta gatgcaaggc tatttggaga tataattaga aaattaccag attcctttgt
   140041 tgagatagaa actgattcag aaaataatat ttacataaat tgtgtaaatt caagatttaa
   140101 aattaaaggt tatgcagcaa aagaatttcc taaattacca gaattaaatg aagaagattt
   140161 atatagcata cctcaagaaa tcctaaaaaa tatgattaaa caaactgtat ttgctatctc
   140221 acaggaccaa acaaaacctg ttttaatggg agaactttta gaaattgtag atagaaactt
   140281 aaatttagta gcaattgatg gatatagatt agctgtaaaa agttgttcag ttgatagttt
   140341 aactgaaaat ataaaagtca taattcctgg aaagacactt atagatgtaa atagtttgct
   140401 ttctggagag gataatgtta aagttggatt taacgaaaaa aatgctattt ttataattaa
   140461 tgatacgaaa attattacaa gattgcttga aggagatttt attgattata aaaaattatt
   140521 gccaagagaa cataacagca gagttaaatt aaatactaag gaacttttaa atagtataga
   140581 gagagcgtct ttattgtctc aatcagaaaa aaataatctt ataaagttat ctataagaga
   140641 taaagtaatg gcaattactt ctaatacaga aaaaggaaat gtgtatgaag aagttgaaat
   140701 agatttagat ggagattacc tagatatagc tttcaattct agatatttta tcgaaggttt
   140761 gaaaaatata gataatgagg aaatatttat agaatttact acaaatgtaa atccttgtat
   140821 aattaaacca acagatgatg ttaattatat ttacttactg cttccagtaa gaatatcatc
   140881 aaatatatag cagacatgaa ggagttgtct tttgtagaaa atttttctaa tcttagacaa
   140941 ctccttttat aagcatattt atggtataat atacttttag tgtatcaata ggaatttgtt
   141001 taaaatagtg acaaggagga actattatga ctgaaataac tatagaatca gaatatataa
   141061 agttggatca atttcttaaa ttagcagaga ttgcatcaac aggaggtcat gcaaaatttt
   141121 taattcaaga aggtttagtg acagtaaatg atgaaataga attaagaaga ggaaaaaaga
   141181 taaaatcagg agatatagtt gaaatagaag gaactaaaat aaaagtattg taaaaaaagg
   141241 agaacttttt gtgaaactta aaagtttgca acttgttaat tttagaaatt ataaaaagtt
   141301 gcatctggaa tttaatggga aagtaaatct acttgttggt aaaaatggtc aaggaaagac
   141361 aaatatagta gaatctattt atatgctttc ttttggaaaa tcatttagga ctaacaaaga
   141421 taaagaaatg gttagattta atagtgaaaa cttatatatt ggaggaagtt tttcaaaata
   141481 taataaatat agtctaatag agctaattat tggaaaagat aaaaaaggga taagaataaa
   141541 taaagttcct ttacaaaaga tacaagaact acttggcaac ttaaatgttg ttatattttc
   141601 tcctgaggat ttaaggttgg ttaaagaggg tcctaaagaa agaagggcat ttatagacaa
   141661 agagattagt cagattatac ctaaatatta taaatatctt accaattata ataaaacact
   141721 ttctcaaagg agtagggtgc ttaaaaatat acatgttgat gaagctttat tagatgtata
   141781 tgatgatacg ttagcaaagt atggaagtta tatttatatt ttgcgtagag actttataaa
   141841 aaagatagct aatatatctg aaaatatgca tatgaatttg actaatggag ttgaaagatt
   141901 atcaattcga tataaaaatc aaataaatat aactgatgaa gatactatag atacagtata
   141961 taataaattt ttagccaagt tgtcatcgaa tagacctaat gatatagaat ctaagactac
   142021 cagatatggt atacacaaag atgacttaaa tatattcata aatgatttag atgcaagact
   142081 ttttggttca caaggtcaac aaagaactgc ttcaatatca ttaaagttat cagagataga
   142141 attaataaaa aatgaagttg aagaatatcc agtattaatt ttagatgatg tttttagtga
   142201 gttagatgaa gcaagacaaa aacttttagt aaataattta agcaatgttc aaatgtttat
   142261 aacaagtgct gaagtttcac ataaaaaaat atttgatgaa aaaaatgtta caatatttaa
   142321 tattgaaaat ggcgatgtta ttagcataga gaatggagga aattaaatga aacaagaata
   142381 cggtgcaagt cagatacaag tattagaggg attagaagcc gttagaaaaa gaccaggtat
   142441 gtatattggt agtacaagcc ctagaggttt acatcactta gtttatgaag ttgtagataa
   142501 tagtatagat gaggctttac aaggatattg ttcagacata tatgtatcta ttaatgaaga
   142561 tggcagtgtt ttagtaaaag ataacggaag aggtatacct gttgaaatac atcctaaaac
   142621 tggtaaatca actttagaaa cagtattaac taatcttcat gcaggaggaa agtttggagg
   142681 cggaggatat aaagtatctg gaggtcttca tggagttggt gtttctgtag ttaatgcatt
   142741 gtcaaaatgg atgatagcag aggtttattt aaacggaaag atatataagc agacatatga
   142801 gaaaggattg ccaacatcta agcttgaagt agttggagaa tctcaagata aaggaacaat
   142861 gattcaattt atgccagatg agacaatatt tgatgaaata gagtttaaat atgaaacatt
   142921 ggagtatagg cttagagaac tttctttctt gaataaagga ataaaaatag tatttgaaga
   142981 taaaagagaa ggacaagaaa aaagaaaaga atttcactat acaggtggtt tggtagaata
   143041 tattaagtat ttaaataaat ctagaactgg tatacatgat gacatagttt atatagataa
   143101 aaaggttgat gattgttttg ttgaactagc tatgcaatat acagatggtt atacagagaa
   143161 catatattct tttgcaaaca atataaatac acatgaaggt ggttctcatt taagtggatt
   143221 taaagcagct cttactaaaa ctgtaaatga ttatgctaag agaaataaat ttttaaagga
   143281 aaatgatgtt aacctacttg gtgaagacat aagagaaggt cttacagcag tagtatcagt
   143341 taaattacca gaacctcaat ttgaaggtca aactaaaaca aagctaggta atagctttat
   143401 gagaggtata gttgatagtg taacagttga tgaactgggg tctttcctag aagaaaaccc
   143461 atcaacagca agaatcatag ttgataaagc tttaagagca caaagagcta gagaagctgc
   143521 aaaaaaagca agagaattaa caaggagaaa aagtgtatta gaaagtacat ctttacctgg
   143581 aaaacttgca gattgtgcag aaaaagatcc atctaaaagt gaaatattct tagtcgaagg
   143641 ggattcagcg ggaggttcag ctaaacaagg tagagataga aatagtcaag ctatacttcc
   143701 attaagaggg aaaatactta atgttgagaa atcaagacta gataggatac tatcttcaga
   143761 tgaaataaaa aatatgataa cagcttatgg ttgtggtatt ggagaagatt ttgatataga
   143821 taaggctagg tatcataaaa ttataattat gaccgatgct gatgtagacg gagcccatat
   143881 aagaacttta ttattaacat tcttctttag atatatgaga cctcttatag atgaggggta
   143941 tgtttatgca gcacagccac ctttatataa agtgacaaag caaaagaagg aacattatgt
   144001 ttactcagat aaagagttaa atatcttact agatgaaatt ggaagaaatg gtgttgaact
   144061 tcaaaggtac aaaggtcttg gagagatgaa tgcagagcaa ttatgggaaa caactatgaa
   144121 tcctgagaca agaactttat tacaagttac tgtagaagat gctgcaattg cagatgaagt
   144181 attttcaatg cttatgggtg ataaggttgc tccaagaaaa gaatttatag aagaaaatgc
   144241 aagatttgtt agaaacttag atatatagag agaggggatt agtatacatg gaagaaaata
   144301 acaaaatact ccctattgaa atagcggaag aaatgaaaaa atcgtatatt gattattcaa
   144361 tgagtgttat agctggacgt gctcttcctg atgttagaga tggtttaaag ccagttcata
   144421 gaagaatatt atattcaatg agtgagttaa atttaactcc agataaacca tacaggaagt
   144481 cagctcgtat tgttggggac gttttaggta agtaccatcc tcatggagat actgctgttt
   144541 attatgctat ggtaagaatg gcacaagatt tttcaactag agcactttta gtagatggtc
   144601 atggtaactt tggttctgtt gatggggatt caccagctgc tatgcgttat acagaagcta
   144661 aaatgagtaa attatcatta gaactactga gagatattga aaaggaaact gtagacttta
   144721 aaccaaactt tgatgagtcg ttaaaagagc cttcagtatt gccagctaga tatcctaatt
   144781 tattagtaaa tggctcaaat ggtatagctg ttggtatggc aacttcaata cctccacata
   144841 atttagcaga agtaattgat gcaactgtat atttgataga taatccagag tgtagtgtag
   144901 atgatttaat aaaatttgtt caaggaccag atttccctac agctgcaatt ataatgggaa
   144961 aagaaagtat agcagaagca tacagaactg gaagaggaaa agttaaagtt aggtctagag
   145021 cttttataga agagctacca aaaggaaaac agcaaataat agttacagaa ataccttatc
   145081 aagtaaataa ggctaaactg gttgaaagaa tagcagagtt agttaaagaa aagagaatag
   145141 aaggtatatc agacctaaga gacgaaagta atagaaatgg tatgagaatt gttatagaat
   145201 taaagaggga tgctaatgct aatatagtat taaataattt gtataaacat tctcaaatgg
   145261 aagatacttt tagtataata atgcttgcac ttgtagatgg tcagccaaga gttttaaatc
   145321 ttaaacaaat attatatcat tatattaaac atcaagaaga tgttgttaca agaagaacta
   145381 aatttgaact aaataaagct gaagcaagag cacatatttt agaaggatta aagattgctt
   145441 tagataatat agatgctgtt ataagcttga taagagcttc aaagactggg caagaagcta
   145501 agctaggttt aatagaaaaa ttcaaattaa ctgaaatcca agcacaagct atattagata
   145561 tgagacttca aagacttaca ggtttagaaa gagataagat agaagctgaa tatgaagatt
   145621 taatcaagaa gataaataga ttaaaagaga ttttagctga tgaaagatta cttttaaatg
   145681 taataaagga tgaaattaca ataataaaag aaaattactc tgatgagaga agaacagaaa
   145741 taagacatgc tgaaggcgaa atagatatga gagatcttat aagtgatgaa gaaatagcaa
   145801 taactcttac tcactttgga tatataaaaa ggcttccatc tgatacttat aagagtcaaa
   145861 aaaggggtgg aagaggtatt tcagcactta caactagaga agaagatttt gtaaggcact
   145921 tggtaactac aactactcat agtagactat tattctttac aaataaaggt agagtattta
   145981 aattaaatgc atatgaaata ccagaaggta agagacaggc taaaggtact gctatagtga
   146041 atttacttca attgtcagca gatgagaaaa ttgctactct aatacctatt gatggtaatg
   146101 atgaaaatga atatttatta cttgcaacga aaaaaggtat tgttaaaaag actaagagag
   146161 aagagttcaa aaatataaat aaatctggtc ttattgcaat aggtttaaga gatgatgatg
   146221 agcttattgg agtagaactt acagatggaa aacaagaagt acttttagta actaaagaag
   146281 gtatgtctat aagatttgat gaaaatgata taagatatat gggtagaaca gcaatgggtg
   146341 taaaaggtat aactttaagt aaagaagatt ttgttgtgtc tatgaacctt tgcagtaaag
   146401 gtacagatgt gttagttgta agtaagaatg gttttggaaa gagaacaaat atagaagagt
   146461 atagaagtca aataagagct ggtaaaggaa ttaaaactta taatatatct gaaaaaactg
   146521 gtacaattgt aggtgcagat atggtcaacg aagatgatga gataatgatt ataaattctg
   146581 atggagttct tattagaata agagtcaatg aaatatcact gtttggaaga gttacaagtg
   146641 gtgttaaatt aatgaagacg aatgatgaag tcaatgtagt ttcgattgcc aaaataaata
   146701 ttgaagaaga ataggataaa tatcctattc tttttgtata atgtagttag ataaaaattt
   146761 aaaattgaaa ggagtaattg ttatgtgcaa taaaagaagt tgtaaaaaag gtggattttt
   146821 attattagga gctattttag ggtttatatt tggtatgttt tttgcaccta aaaaaggttc
   146881 tgaactaaga aaagaaacaa aagagaagtt taatgatgtc aaagaaaatc caaaagaagt
   146941 tctacatgaa acatttaatg atgttaaaga gagaataata aatttagtgg atgatgataa
   147001 taatgaagaa gatataaaga tttcagaaga agatatagta ataagtaaaa gctttgatga
   147061 tgagggagat gttaactaat gaatgcatgg gggtggcaaa ttggagcagt gttagtagga
   147121 agctctgctc ttatagtagc aatttattta gctaaaactc taaacagcat aaataaggtt
   147181 gttgaaaagg catataagat tgtagattat aatgaaagac atatacaaga tattgttgaa
   147241 aatgcatcat caatatcaaa gggaatagat gatatagttt atgtaattaa taaaatattg
   147301 agtataggaa atatatttaa aattattaaa aggaaatagg aggtttttac atgtctatga
   147361 atattgattc aaatttagat tcacaaaata aattttggaa tgtttgtctt gatggagaac
   147421 ttgatgtttc tacagcagat aaactaaagg aacatttaca tgctttaata gaaaaaaata
   147481 tgttagatgt aaagattaat cttaaagatt tagattatat agactcaaca ggcttaggag
   147541 ctatgatagg tgtattaaaa aaattaaaaa taaatgaaaa agagatatac atattaaatc
   147601 ctaagagtaa cgtaagaaag atttttacta taacaggtct agataaaata tttaaagtgg
   147661 agggataaac tttggcttgt gagactataa agatggaaat tactacaaat ccagattatg
   147721 ttagtataat aagattaaca gcatctggaa ttgccaataa gatgggtttt ccaatagatg
   147781 atatagaaga tataaaggta gcagtatctg aagcatgcac aaatgcaata aaacacagta
   147841 aagatgatgt gtttaatata gtatttaata ttttagataa tgcaattaat atagaaattc
   147901 aagataatgg aaaaggatat gatgttagct caataagtac accagattta gagaatccaa
   147961 aagagagtgg tcttggattg tttataatta aaactttaat ggatgatgta gatattgaat
   148021 cagaacataa tcaagggaca aaaataaaaa tgactaaata tttaggagtt gatatttaat
   148081 gaaaaatgta gctaatgcta cacattacct aaatatggat acaaaagagc tatttaattt
   148141 atataataaa aataaaaatg tagacattag aaatattctt attgaaagac atctgtattt
   148201 agcaagattg ttagctaaga agtatataaa caaaggtgtt gattttgaag atatatatca
   148261 agttgcttca ttggcattaa tttatgctat tgatagatat gatgttgaga aaggatttga
   148321 gttctccagc tttgcaacac caactatagt aggagaaata aaaaagtatt ttagagataa
   148381 agtatggaca cttagagtcc caagaagaat acaggaatta agcaaaaaga taagtgatgc
   148441 gaagattaaa ttagaacaag aaaataagaa gcatccaaag gtaaaagata tagctgatta
   148501 tataggcgtt agtgaagaag atgttttaga ggctatggag gcttcttatg gatatcaacc
   148561 aatgtctttg gattcatcaa gtaatgatga ttcagaggat aaagatataa ctcttattga
   148621 taagattgga aaagaagaag gtaactttgg aagtatagag tatgaagatt ttattaataa
   148681 gtttattgaa actttaaatg aattagaagt taaaattttt aaagatagat ttttctttga
   148741 taaaactcaa tctagtatag ctaaagaact agggatatca cagatgactg tttctagact
   148801 agagaaaaag gtagtagaga agttgaaaaa agaatatgaa aaaaatttat aaaaaaatat
   148861 aaaaaaagta ttgacctact gttttaaaga tggtatagta ttacttgtcc ttgaaaaaag
   148921 gaacaagaaa taaacacgaa cattgaaaat taaacagtag gt
//
LOCUS       DAEPUT010000002       131226 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.002, whole genome shotgun sequence.
ACCESSION   DAEPUT010000002 DAEPUT010000000
VERSION     DAEPUT010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 131226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 131226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..131226
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.002"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..634
                     /locus_tag="KRL22_000151"
     CDS             <1..634
                     /locus_tag="KRL22_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBH1270677.1"
                     /translation="TLGMSIFIAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLI
                     GTDFCLMVLLYITSIGSIKSRIKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQF
                     FTTLLSIKTKLSTAMNITTLLVIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYN
                     NPNDPSLMVNKRFGIGWTINFGNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            754..1230
                     /locus_tag="KRL22_000152"
     CDS             754..1230
                     /locus_tag="KRL22_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH1270678.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            1616..2083
                     /locus_tag="KRL22_000153"
     CDS             1616..2083
                     /locus_tag="KRL22_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH1270679.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(2143..2715)
                     /locus_tag="KRL22_000154"
     CDS             complement(2143..2715)
                     /locus_tag="KRL22_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH1270680.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGTPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(2778..3875)
                     /locus_tag="KRL22_000155"
     CDS             complement(2778..3875)
                     /locus_tag="KRL22_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBH1270681.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            complement(3889..4578)
                     /locus_tag="KRL22_000156"
     CDS             complement(3889..4578)
                     /locus_tag="KRL22_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH1270682.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            complement(4743..5909)
                     /gene="rpoD"
                     /locus_tag="KRL22_000157"
     CDS             complement(4743..5909)
                     /gene="rpoD"
                     /locus_tag="KRL22_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBH1270683.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            complement(5927..7717)
                     /locus_tag="KRL22_000158"
     CDS             complement(5927..7717)
                     /locus_tag="KRL22_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBH1270684.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            complement(7972..8757)
                     /gene="aroF"
                     /locus_tag="KRL22_000159"
     CDS             complement(7972..8757)
                     /gene="aroF"
                     /locus_tag="KRL22_000159"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH1270685.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            complement(8738..9244)
                     /gene="folK"
                     /locus_tag="KRL22_000160"
     CDS             complement(8738..9244)
                     /gene="folK"
                     /locus_tag="KRL22_000160"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBH1270686.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            complement(9237..9602)
                     /gene="folB"
                     /locus_tag="KRL22_000161"
     CDS             complement(9237..9602)
                     /gene="folB"
                     /locus_tag="KRL22_000161"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HBH1270687.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRARDE"
     gene            complement(9613..10404)
                     /gene="folP"
                     /locus_tag="KRL22_000162"
     CDS             complement(9613..10404)
                     /gene="folP"
                     /locus_tag="KRL22_000162"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH1270688.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            complement(10468..11040)
                     /gene="folE"
                     /locus_tag="KRL22_000163"
     CDS             complement(10468..11040)
                     /gene="folE"
                     /locus_tag="KRL22_000163"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBH1270689.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            complement(11066..11767)
                     /locus_tag="KRL22_000164"
     CDS             complement(11066..11767)
                     /locus_tag="KRL22_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270690.1"
                     /translation="MIGCIYEVYNEEITKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRDIYLEGPSKMSLEEKSFIKQDIGTKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            complement(11801..12544)
                     /locus_tag="KRL22_000165"
     CDS             complement(11801..12544)
                     /locus_tag="KRL22_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HBH1270691.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            complement(12534..13883)
                     /gene="pabB"
                     /locus_tag="KRL22_000166"
     CDS             complement(12534..13883)
                     /gene="pabB"
                     /locus_tag="KRL22_000166"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HBH1270692.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            complement(13885..14469)
                     /locus_tag="KRL22_000167"
     CDS             complement(13885..14469)
                     /locus_tag="KRL22_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HBH1270693.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            complement(14492..15211)
                     /locus_tag="KRL22_000168"
     CDS             complement(14492..15211)
                     /locus_tag="KRL22_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1270694.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            complement(15239..16303)
                     /locus_tag="KRL22_000169"
     CDS             complement(15239..16303)
                     /locus_tag="KRL22_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH1270695.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            complement(16447..17256)
                     /locus_tag="KRL22_000170"
     CDS             complement(16447..17256)
                     /locus_tag="KRL22_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270696.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            complement(17498..18364)
                     /locus_tag="KRL22_000171"
     CDS             complement(17498..18364)
                     /locus_tag="KRL22_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1270697.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            complement(18884..19573)
                     /locus_tag="KRL22_000172"
     CDS             complement(18884..19573)
                     /locus_tag="KRL22_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBH1270698.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            complement(19566..19937)
                     /locus_tag="KRL22_000173"
     CDS             complement(19566..19937)
                     /locus_tag="KRL22_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBH1270699.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            complement(20119..21465)
                     /locus_tag="KRL22_000174"
     CDS             complement(20119..21465)
                     /locus_tag="KRL22_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1270700.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            complement(21647..22240)
                     /locus_tag="KRL22_000175"
     CDS             complement(21647..22240)
                     /locus_tag="KRL22_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HBH1270701.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            complement(22305..23774)
                     /locus_tag="KRL22_000176"
     CDS             complement(22305..23774)
                     /locus_tag="KRL22_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH1270702.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVVINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            complement(23885..25276)
                     /locus_tag="KRL22_000177"
     CDS             complement(23885..25276)
                     /locus_tag="KRL22_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBH1270703.1"
                     /translation="MYFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLVQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            complement(25442..25690)
                     /locus_tag="KRL22_000178"
     CDS             complement(25442..25690)
                     /locus_tag="KRL22_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270704.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSTNKKQKSHSRDIKRKIS"
     gene            25956..28085
                     /locus_tag="KRL22_000179"
     CDS             25956..28085
                     /locus_tag="KRL22_000179"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBH1270705.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYDKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            complement(28327..28926)
                     /locus_tag="KRL22_000180"
     CDS             complement(28327..28926)
                     /locus_tag="KRL22_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HBH1270706.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(28944..32063)
                     /locus_tag="KRL22_000181"
     CDS             complement(28944..32063)
                     /locus_tag="KRL22_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBH1270707.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPVEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     NFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKGGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            32284..33108
                     /gene="pdaA"
                     /locus_tag="KRL22_000182"
     CDS             32284..33108
                     /gene="pdaA"
                     /locus_tag="KRL22_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH1270708.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            complement(33205..33990)
                     /locus_tag="KRL22_000183"
     CDS             complement(33205..33990)
                     /locus_tag="KRL22_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1270709.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            34455..34820
                     /locus_tag="KRL22_000184"
     CDS             34455..34820
                     /locus_tag="KRL22_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1270710.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            34898..35452
                     /locus_tag="KRL22_000185"
     CDS             34898..35452
                     /locus_tag="KRL22_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH1270711.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            35672..36346
                     /locus_tag="KRL22_000186"
     CDS             35672..36346
                     /locus_tag="KRL22_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH1270712.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     regulatory      36701..36797
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            36851..37027
                     /locus_tag="KRL22_000187"
     CDS             36851..37027
                     /locus_tag="KRL22_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270713.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            complement(37214..37453)
                     /locus_tag="KRL22_000188"
     CDS             complement(37214..37453)
                     /locus_tag="KRL22_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270714.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNIDRNWCKDKK"
     gene            complement(37598..38407)
                     /locus_tag="KRL22_000189"
     CDS             complement(37598..38407)
                     /locus_tag="KRL22_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1270715.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            39191..41425
                     /locus_tag="KRL22_000190"
     CDS             39191..41425
                     /locus_tag="KRL22_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1270716.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQYIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNIGATIIESARELKIKLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLAMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            41456..42301
                     /locus_tag="KRL22_000191"
     CDS             41456..42301
                     /locus_tag="KRL22_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1270717.1"
                     /translation="MFKEIFLKTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFMDSHNIQLDWEKNYPYDKISNWIFEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            42541..44274
                     /locus_tag="KRL22_000192"
     CDS             42541..44274
                     /locus_tag="KRL22_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1270718.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDNTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   44666..44894
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=44731..44759
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(45173..45325)
                     /locus_tag="KRL22_000193"
     CDS             complement(45173..45325)
                     /locus_tag="KRL22_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270719.1"
                     /translation="MDNFLQGVLASLVASLIVYLNSKLFKKVKSHSGRSDFSFELKIK
                     FKKNKH"
     gene            46449..47804
                     /locus_tag="KRL22_000194"
     CDS             46449..47804
                     /locus_tag="KRL22_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1270720.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(47922..48590)
                     /locus_tag="KRL22_000195"
     CDS             complement(47922..48590)
                     /locus_tag="KRL22_000195"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HBH1270721.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(48657..49085)
                     /locus_tag="KRL22_000196"
     CDS             complement(48657..49085)
                     /locus_tag="KRL22_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH1270722.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            49192..49785
                     /locus_tag="KRL22_000197"
     CDS             49192..49785
                     /locus_tag="KRL22_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBH1270723.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            49905..50840
                     /locus_tag="KRL22_000198"
     CDS             49905..50840
                     /locus_tag="KRL22_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBH1270724.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(51111..52055)
                     /locus_tag="KRL22_000199"
     CDS             complement(51111..52055)
                     /locus_tag="KRL22_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH1270725.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIMYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKICYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            52373..53803
                     /locus_tag="KRL22_000200"
     CDS             52373..53803
                     /locus_tag="KRL22_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1270726.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            54003..54587
                     /locus_tag="KRL22_000201"
     CDS             54003..54587
                     /locus_tag="KRL22_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HBH1270727.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(54691..55470)
                     /locus_tag="KRL22_000202"
     CDS             complement(54691..55470)
                     /locus_tag="KRL22_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1270728.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(55528..56784)
                     /locus_tag="KRL22_000203"
     CDS             complement(55528..56784)
                     /locus_tag="KRL22_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBH1270729.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            57042..57941
                     /locus_tag="KRL22_000204"
     CDS             57042..57941
                     /locus_tag="KRL22_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBH1270730.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            57965..59413
                     /gene="ddlR"
                     /locus_tag="KRL22_000205"
     CDS             57965..59413
                     /gene="ddlR"
                     /locus_tag="KRL22_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HBH1270731.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            59472..60278
                     /locus_tag="KRL22_000206"
     CDS             59472..60278
                     /locus_tag="KRL22_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1270732.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            60304..62223
                     /locus_tag="KRL22_000207"
     CDS             60304..62223
                     /locus_tag="KRL22_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1270733.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKKESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(62465..62812)
                     /locus_tag="KRL22_000208"
     CDS             complement(62465..62812)
                     /locus_tag="KRL22_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HBH1270734.1"
                     /translation="MSKSNDVLDIVFKITVGLEYEVAENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(62799..64727)
                     /locus_tag="KRL22_000209"
     CDS             complement(62799..64727)
                     /locus_tag="KRL22_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HBH1270735.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            complement(65138..67327)
                     /locus_tag="KRL22_000210"
     CDS             complement(65138..67327)
                     /locus_tag="KRL22_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HBH1270736.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEIPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
     gene            67658..68389
                     /locus_tag="KRL22_000211"
     CDS             67658..68389
                     /locus_tag="KRL22_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH1270737.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMNIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLTNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            68469..69104
                     /locus_tag="KRL22_000212"
     CDS             68469..69104
                     /locus_tag="KRL22_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH1270738.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNKVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(69354..69947)
                     /locus_tag="KRL22_000213"
     CDS             complement(69354..69947)
                     /locus_tag="KRL22_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HBH1270739.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(70018..70881)
                     /locus_tag="KRL22_000214"
     CDS             complement(70018..70881)
                     /locus_tag="KRL22_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBH1270740.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            71044..72213
                     /locus_tag="KRL22_000215"
     CDS             71044..72213
                     /locus_tag="KRL22_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1270741.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVILHVKNVLSF"
     gene            72314..72790
                     /locus_tag="KRL22_000216"
     CDS             72314..72790
                     /locus_tag="KRL22_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH1270742.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSIPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            73356..74150
                     /locus_tag="KRL22_000217"
     CDS             73356..74150
                     /locus_tag="KRL22_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HBH1270743.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            74174..74617
                     /locus_tag="KRL22_000218"
     CDS             74174..74617
                     /locus_tag="KRL22_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HBH1270744.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(74706..75992)
                     /locus_tag="KRL22_000219"
     CDS             complement(74706..75992)
                     /locus_tag="KRL22_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH1270745.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(76210..77100)
                     /locus_tag="KRL22_000220"
     CDS             complement(76210..77100)
                     /locus_tag="KRL22_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH1270746.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            77392..77736
                     /locus_tag="KRL22_000221"
     CDS             77392..77736
                     /locus_tag="KRL22_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH1270747.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPSRACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(77895..79991)
                     /locus_tag="KRL22_000222"
     CDS             complement(77895..79991)
                     /locus_tag="KRL22_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HBH1270748.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPFEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(80004..81164)
                     /locus_tag="KRL22_000223"
     CDS             complement(80004..81164)
                     /locus_tag="KRL22_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH1270749.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(81183..82250)
                     /locus_tag="KRL22_000224"
     CDS             complement(81183..82250)
                     /locus_tag="KRL22_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HBH1270750.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIRKAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            82602..83168
                     /locus_tag="KRL22_000225"
     CDS             82602..83168
                     /locus_tag="KRL22_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1270751.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(83387..84373)
                     /locus_tag="KRL22_000226"
     CDS             complement(83387..84373)
                     /locus_tag="KRL22_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HBH1270752.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(84403..85098)
                     /gene="pxpB"
                     /locus_tag="KRL22_000227"
     CDS             complement(84403..85098)
                     /gene="pxpB"
                     /locus_tag="KRL22_000227"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBH1270753.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEVEKNNLSI"
     gene            complement(85118..86338)
                     /locus_tag="KRL22_000228"
     CDS             complement(85118..86338)
                     /locus_tag="KRL22_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HBH1270754.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(86367..87158)
                     /locus_tag="KRL22_000229"
     CDS             complement(86367..87158)
                     /locus_tag="KRL22_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HBH1270755.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            87746..88375
                     /locus_tag="KRL22_000230"
     CDS             87746..88375
                     /locus_tag="KRL22_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1270756.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(88489..90003)
                     /gene="glpK"
                     /locus_tag="KRL22_000231"
     CDS             complement(88489..90003)
                     /gene="glpK"
                     /locus_tag="KRL22_000231"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH1270757.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            90247..90789
                     /locus_tag="KRL22_000232"
     CDS             90247..90789
                     /locus_tag="KRL22_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1270758.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            90803..93295
                     /locus_tag="KRL22_000233"
     CDS             90803..93295
                     /locus_tag="KRL22_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1270759.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            93716..94114
                     /locus_tag="KRL22_000234"
     CDS             93716..94114
                     /locus_tag="KRL22_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1270760.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(94331..94540)
                     /locus_tag="KRL22_000235"
     CDS             complement(94331..94540)
                     /locus_tag="KRL22_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270761.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(94572..94781)
                     /locus_tag="KRL22_000236"
     CDS             complement(94572..94781)
                     /locus_tag="KRL22_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1270762.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            95080..95499
                     /locus_tag="KRL22_000237"
     CDS             95080..95499
                     /locus_tag="KRL22_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1270763.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            95727..96182
                     /locus_tag="KRL22_000238"
     CDS             95727..96182
                     /locus_tag="KRL22_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270764.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHIKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(96390..96650)
                     /locus_tag="KRL22_000239"
     CDS             complement(96390..96650)
                     /locus_tag="KRL22_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270765.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(96913..97266)
                     /locus_tag="KRL22_000240"
     CDS             complement(96913..97266)
                     /locus_tag="KRL22_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270766.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANAEIYEMLLNQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(97283..102604)
                     /locus_tag="KRL22_000241"
     CDS             complement(97283..102604)
                     /locus_tag="KRL22_000241"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270767.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGHGNTMLIDNKGTLKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDVFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNALISQYT
                     EISLSNVTDAYSSYNATFIVVDEKKVYATGINTNYLLGFSTSDGSNVNLGLLSDWYYI
                     NISGSSYSRVSCTNNITKINNIIIYEYVTVFCTNIGSFLTGYHGTSWTKPTDSSYRVQ
                     YQGISYAGYLDSYIYNYYPTRCTQSSSSTTFAYLYNGESSSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKFINVNRFTDNSKHAFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNIFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYLCNDVSIIVKNDNTCYVCGLVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNMIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTFT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIITTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(102621..103604)
                     /locus_tag="KRL22_000242"
     CDS             complement(102621..103604)
                     /locus_tag="KRL22_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH1270768.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(103605..104303)
                     /locus_tag="KRL22_000243"
     CDS             complement(103605..104303)
                     /locus_tag="KRL22_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBH1270769.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMISREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(104300..105352)
                     /locus_tag="KRL22_000244"
     CDS             complement(104300..105352)
                     /locus_tag="KRL22_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH1270770.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKMHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(105345..105773)
                     /locus_tag="KRL22_000245"
     CDS             complement(105345..105773)
                     /locus_tag="KRL22_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH1270771.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDILSANVKVSTIYGEVEINV"
     gene            complement(105773..106099)
                     /locus_tag="KRL22_000246"
     CDS             complement(105773..106099)
                     /locus_tag="KRL22_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBH1270772.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(106115..107644)
                     /locus_tag="KRL22_000247"
                     /pseudo
     CDS             complement(106115..107644)
                     /locus_tag="KRL22_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
     gene            complement(107926..108348)
                     /locus_tag="KRL22_000248"
     CDS             complement(107926..108348)
                     /locus_tag="KRL22_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270773.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(108348..110801)
                     /locus_tag="KRL22_000249"
     CDS             complement(108348..110801)
                     /locus_tag="KRL22_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270774.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(110801..110968)
                     /locus_tag="KRL22_000250"
     CDS             complement(110801..110968)
                     /locus_tag="KRL22_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270775.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(110995..111441)
                     /locus_tag="KRL22_000251"
     CDS             complement(110995..111441)
                     /locus_tag="KRL22_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH1270776.1"
                     /translation="MSENGLLKNINIVDLLLNADTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(111567..111995)
                     /locus_tag="KRL22_000252"
     CDS             complement(111567..111995)
                     /locus_tag="KRL22_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH1270777.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(112009..113073)
                     /locus_tag="KRL22_000253"
     CDS             complement(112009..113073)
                     /locus_tag="KRL22_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBH1270778.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESKVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(113078..113521)
                     /locus_tag="KRL22_000254"
     CDS             complement(113078..113521)
                     /locus_tag="KRL22_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270779.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEVSDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTLTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(113770..114210)
                     /locus_tag="KRL22_000255"
     CDS             complement(113770..114210)
                     /locus_tag="KRL22_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270780.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(114315..114512)
                     /locus_tag="KRL22_000256"
     CDS             complement(114315..114512)
                     /locus_tag="KRL22_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1270781.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQS"
     gene            114681..115001
                     /locus_tag="KRL22_000257"
     CDS             114681..115001
                     /locus_tag="KRL22_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1270782.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVVAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            115083..115589
                     /locus_tag="KRL22_000258"
     CDS             115083..115589
                     /locus_tag="KRL22_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270783.1"
                     /translation="MNNLDKLFELASQEGIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            116290..117045
                     /locus_tag="KRL22_000259"
     CDS             116290..117045
                     /locus_tag="KRL22_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1270784.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(117188..117616)
                     /locus_tag="KRL22_000260"
     CDS             complement(117188..117616)
                     /locus_tag="KRL22_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH1270785.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(118037..118237)
                     /locus_tag="KRL22_000261"
     CDS             complement(118037..118237)
                     /locus_tag="KRL22_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1270786.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(118420..119589)
                     /locus_tag="KRL22_000262"
     CDS             complement(118420..119589)
                     /locus_tag="KRL22_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HBH1270787.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            119825..120646
                     /locus_tag="KRL22_000263"
     CDS             119825..120646
                     /locus_tag="KRL22_000263"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HBH1270788.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(120722..122110)
                     /locus_tag="KRL22_000264"
     CDS             complement(120722..122110)
                     /locus_tag="KRL22_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HBH1270789.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLFLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGNLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVCNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(122245..123003)
                     /locus_tag="KRL22_000265"
     CDS             complement(122245..123003)
                     /locus_tag="KRL22_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH1270790.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSSVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIACNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     SYQSTGLICGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(123005..123721)
                     /locus_tag="KRL22_000266"
     CDS             complement(123005..123721)
                     /locus_tag="KRL22_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH1270791.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLICSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(123723..124430)
                     /locus_tag="KRL22_000267"
     CDS             complement(123723..124430)
                     /locus_tag="KRL22_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH1270792.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEELFMKVVAENRKRGE"
     gene            complement(124546..125082)
                     /locus_tag="KRL22_000268"
     CDS             complement(124546..125082)
                     /locus_tag="KRL22_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1270793.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(125184..126254)
                     /locus_tag="KRL22_000269"
     CDS             complement(125184..126254)
                     /locus_tag="KRL22_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBH1270794.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSISSHLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNNNLHLSTKSILGVKNVNIESESL
                     YISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHDEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(126247..127305)
                     /locus_tag="KRL22_000270"
     CDS             complement(126247..127305)
                     /locus_tag="KRL22_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBH1270795.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(127292..127624)
                     /locus_tag="KRL22_000271"
     CDS             complement(127292..127624)
                     /locus_tag="KRL22_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH1270796.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            127823..128944
                     /locus_tag="KRL22_000272"
     CDS             127823..128944
                     /locus_tag="KRL22_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HBH1270797.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(129072..130970)
                     /locus_tag="KRL22_000273"
     CDS             complement(129072..130970)
                     /locus_tag="KRL22_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HBH1270798.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
BASE COUNT        44518 a        21188 c        14913 g        50607 t
ORIGIN      
        1 tactttggga atgagtattt ttatagcatt taattataat caattgccag actcaattgc
       61 cactcattgg aacataaatg ggtctcctga tgtttttata gataaatcat ttcttaatgt
      121 atttaaatta atcggtactg acttttgttt aatggtttta ttatatataa cttccattgg
      181 atccataaag tcaaggatta agatagatac aaatagaatt gaagaaagta gagttgaaaa
      241 cattaaatat ttaaataaaa ttggttattt gtttttaata ttgatgatta taatgacaac
      301 acagtttttt actactcttt tatcaataaa aacaaaacta tcaactgcta tgaatattac
      361 aacgctttta gttataattt atttaatagc aacatatatt aattccccaa atttaaaatt
      421 caactcatct tattctccag aagaagatga gaagtattgg atagcaggca tcatgtataa
      481 taatccaaat gacccatcat taatggttaa taaaaggttt ggtattggat ggactataaa
      541 ttttggcaat cctcttggaa aaatactata tattgctata gctttacttt taattttttc
      601 attgtttagc ctaataaaat ctctcttact ttaaaatacc ataaaaggta tcttacttgt
      661 attattgggt attatatttt gtaggataag aaatatttca tattatcgtt taagtatagt
      721 atttatatat tactaagaat ggagattttc ataatgttgt caaaagctga aatcaaatat
      781 tttaatgaat gtgcttctga gatactttct tctgaaaaag ttcaacttat gagaacattt
      841 cctcatcatg gcaatgtttc atgtcttgaa catagtttgt cagtagcata ttatagttat
      901 ctattatgta aaaaattgca cttaagtgtt gatattcaaa gtgttattag aggagcttta
      961 ctacacgact tttttcttta tgattggcat tacaaaggtg atagaaaagg attacatgga
     1021 tttactcacc ctagagaagc attaaaaaat gcaactttat tttttcaaat aaatgaaaaa
     1081 gaaacggaca taattttaaa acacatgtgg ccacttactg ttaagccacc tagatacaaa
     1141 gaagcattta ttgtatgttt gttggataaa ttttgctgtt tagttgagac tttaaagata
     1201 cattctttat tatctcctta ccatgtatag gacaattccc acaacacttt tataacttaa
     1261 ttttgaagag gtattaagta ttatattcaa cttgatacct ctttactatt tattatttta
     1321 tataataata ttttctttat aatatagtta taaataacaa cttctaccct cgataacttc
     1381 cccttcttat agacatgctt actatcttaa ataacaagaa accagctatt aaatttatta
     1441 gtattgttta tactactcta acaataatat cataaataaa cctccaaata gcttctcttt
     1501 cactaccttt tatcttaaac tatatttttt tcttaaaatt tgtaaaaaac atagcataat
     1561 ctttataaat gttctaaaat ttaatttaag catcaaaatt agaaaggatg atattatgtt
     1621 taaagaaatg agattgaaaa aaagagaaat gacaaaagaa gatactgttg aagtattaaa
     1681 aaatggtgaa tttggtactt tttccactat atctgaaaat ggttatcctt atggagttgc
     1741 tgtaaattat gtatacttta atgattctat ttactttcat tgtgcaagaa atgggcataa
     1801 gttagataat atatcgaaaa acaacaaagt ttctttttta gtagttgcta atgaaagtgt
     1861 tattccagat aaatttagta ctacttattc tagtgctata gtttttggaa aagcttgcac
     1921 tgtagaaaat gaagaaaaga aaaatgctct tgtagaaata ataaaaaaat attctaaagg
     1981 attctttgaa gaaggcatga agtacataga gaaggatatg aacttaacaa ctgttgttaa
     2041 aatagaaatt gaccatattt ctggtaaagc ttcacgttta taattaagta aaaataccta
     2101 aaagtatata cagtcgcttt taggtatttt tatatgatat tcttatatgt taagtctttt
     2161 taggtaatct cttataccta tcttggcatc atcatttggt cttatatcag aattatctcc
     2221 tgctatatga agtattccat acgctggata acctcctctt actgaacatg gaactgacaa
     2281 aagagtcatt cccatatgtt gggcaaatat attcatagct tgcaaagcta attctcctcc
     2341 tccatgttgt gaacctgctg tagcaaaaca accaaatatt ttaccactca aaggagtacc
     2401 tacccaaata tcagaaaaac tatccataaa catcttcatt ggtccagata catttccata
     2461 atatgttggt gaacccataa atatagcatc ataatctaat atttcttttc cagatttaat
     2521 tacatttata ctttcaaatt cgtctttgta ttctttggaa tttatcaaat aatattgagg
     2581 aagtgttttt gcaacttcgt cacttactct aaatatatct acctcgatat tcatttcttc
     2641 aagcgcttct ttatattctc tagctaataa atatgtactc ccacaaacac tatgaaaaat
     2701 tactgctact ttcatcatta tccccctaat taaactcaaa tttatttttt atatagtatt
     2761 tttattatca aacactgcta aatagtacta aatggattca aatatacatt actttttatt
     2821 acttcaattt cactaaattc atctaaaaat ctcttcataa catttttgaa tatatcttct
     2881 gtatcaaaat gaccacaatc cactatacac attccaatat caagtgcatc ttgtgcctca
     2941 tgatacttta catcacccgt aattagtact tctgcacctt gtctcttagc tttttttaca
     3001 aattctgaac cagctcctgt tacaacggct actttcgtta tgtctgtact aaggtttcca
     3061 actactctta tgtgtttcat atttaatttc tcttttattt tccttgaaag actttctaat
     3121 gtcatacttt tatcaagttt acttattcta cctagtccaa atatctcacc tttattttct
     3181 aacttgtaca aatcatatgc aacttcttca taaggatgtg catctaacat agaacttatt
     3241 accccaccta aaagcttctg tggtactaca gtttcaattt taacttcatt tacagtttct
     3301 atatcattta cacttccaag aaacggatta gagccttcta atggcttaaa ttgtccttca
     3361 ccttctattg aaaacgtaca atcactataa ttccctatat gacctgctcc tgaattactt
     3421 aaaacctttc taagttcatc tgaatagtta tgtggaacgt atactgctaa tttatacaaa
     3481 ttttcgcttt tagttatatc taaaaccttt gaattaccaa attccataat ttccataaaa
     3541 tagtcattta gaccatcaaa tgctatatca aaattcgtat gcatagaata aagtgatata
     3601 tcatttttaa taagtttttg gataagtctg ccttttaaat ctccactatt aattttatta
     3661 attttcccaa atataaaagg atgatgtgtc acaattaaat ctatattttt ggatatagct
     3721 tcatcaataa catcttcatt agcttctaaa gataccaata ccttttttac atccatatca
     3781 aaatctccaa ctataagacc tacattatcc caatcctctg ctaagtttag aggatacttt
     3841 ttttcaattt ttctagttag actctttaat agcatatata cctcctattt attttattaa
     3901 attttcaagt ttttttattg caacttcgct ttcctttctc ttcttatcta tagcttcccc
     3961 atttttccct tctaatttat taactataga actatatgtc tttatctttt tttctataaa
     4021 atcattaaaa agagaatctt tgttttctaa aagctttatt ccaacctcat aatatatctc
     4081 atcttctatt atagtatttt tacctgtata tttggcaaca attatctcat atattctaaa
     4141 atcttctctc actaaaactt cttctaaaat ttcatatccg ttgtttaaaa ggtaatatct
     4201 aagttcttct tgtgcttgca ttggctgtaa tattaatttt tctacattat gtgctacttc
     4261 ttttttagcc tcgagaagct cacttatcaa gattccaccc ataccagcaa ttatcacttc
     4321 ttctacttcc cctatttcaa gtatctctat accagaaccc aatcgtaaat caactttatc
     4381 taaaagattg ttctgtatga cttctttatg tgcattgtca agaggtcctt tattaacatc
     4441 cgctagcact gcaaatggta cttttccctc ttttaacaaa tatactggta tgtatccgtg
     4501 gtccgtccct atatcagcta tttttttacc atctgacact aatgatgcta ttttcaataa
     4561 tctatctgtt aatttcaaat ataattctcc tttcaattcc ctttatttat aggatttaat
     4621 ccaagttata gatattagac tgaaataact acaaaaataa aattaaatct ttactacaaa
     4681 atagccatga gatatcactt atctcatggc atttatcaca aaaacatcaa tgatgtatct
     4741 ttttagtcta aataatctct aagttttttt gatctacttg gatgtcttag ttttcttagt
     4801 gcttttgctt ctatctgtct tattctctct ctagttacat caaactcttt tccaacttcc
     4861 tcaagagttc tggctctacc atcctcaaga ccaaatctaa gctttaatac tttttgttct
     4921 ctatcattta atgaaccaag tacatcttct atttgttctt ttaataaaga atatgctgct
     4981 gcctctgctg gggctggagc atcatcatct ggaataaagt cacctaaatg gctatcttct
     5041 tcttctccta ttggtgtttc taaagacaca gggtcttgag ctattttcat tatttctctt
     5101 actttatctt ctgtcatttc catttctttt gcaatttctt ctggttttgg atctcttcca
     5161 agttcttgaa gtagttgtct tgatactctt attagcttat ttatagtctc taccatatga
     5221 actggtattc ttatagttct agcttggtct gcaatagcac gtgttatagc ttgtcttatc
     5281 caccatgttg cataagtact aaacttatat ccttttgtat agtcaaattt ttcgactgct
     5341 tttataagac ctaaatttcc ctcttgtatt aaatccaaga aaagcatacc tcttcctaca
     5401 tatctttttg ctatacttac aactagtctt aagtttgctt caactaacct ttgttttgct
     5461 atctcatcac cttcgtgcat ccttctagca aattctactt cttcatgtgg tttaagtaga
     5521 ggaatttttc ctatttcttt taagtacatt cttacagggt catctatact tatccctttt
     5581 ggtaaagata aatccacagt ttctatttct attgcagaag agtcatcatg tgaaattgcc
     5641 tctgcatctt catctaagtg gcctatactt aaatcgtcat cagcaaccga aaaatctata
     5701 tcagctttat agttttttgt ttctgttatt tctattccca aatttcctaa agtctcataa
     5761 agattttcta cttgatcctt atcaagttca gtctccgaaa aagcttccat tatctctgca
     5821 agtgtcagag aaccttgctt ttttcctttt tctattaatg tcttagcagt aacctttttt
     5881 aactcttttt tattcgattt attttccaca ctcaaacctc ctttctctac aagctcttta
     5941 aaattttatt tatctcaact atttttaaag caatttccat aactctacca tctacctctt
     6001 tcatatcatt attattttct aattcttgtt gttctctcaa caagctatta atttgctctt
     6061 ctaatgagtt ttttctgata tttgttatta ttccttctat ttcttttgtg ttctctaagt
     6121 ttatactatt caaagaaatt gaatttaatt cttttaagta ttcttcggat atgtttaaac
     6181 ttttcaattt gtcaatagtt attttgtcca attcttgatt tttaatcatg taatttaaaa
     6241 tttctttact ttctttcaat aaaaaatcac tttcttctac tttaagtaac gctatttctc
     6301 taattttttt gtcttctaac attattttta ttagagtttc ttcaactaat tgttttccgt
     6361 cttgtctgac ttcgactttt tcaattactt tttcttctat tttcttttga tttttgttat
     6421 tatatggctt attgtaattt ttaccataaa cttctctctt tatagactcg acattaatat
     6481 ctatttgatt gcttaaatac tttgtataaa aatcaatttc aacaggactt gtcaattgtt
     6541 ttataatttt agaagcttct tttgcgaact tcactcgttc ttcatctttt tgaatgttaa
     6601 attctttttt aagatgatct attttatatt ttatgtagtg agtagaaaca tccatagctt
     6661 ttttataatc actaagtccg tattttctta caaattcatc tgggtcttta gcatctttta
     6721 agtctaacac ttttacattg atacctaatt tagtaagtat atctatagct cttaaagtcg
     6781 cttttattcc tgcttcatca gaatcataag atataatagc agtgtccgca tatctcttta
     6841 ttaaaatgcc ttgttgttca gtcaaggctg ttccaagggt tgctactaca ttttttatac
     6901 catactgata aagcgaaatt aaatccatat atccttcaac taagactata gtcttacttt
     6961 ctaaattttt tctagcaaaa tttaatccgt ataagttctg ttttttatta aaaattaatg
     7021 tgtctggaga atttaagtat tttggcaaag aatcgtctaa tactcttccc ccaaatccta
     7081 ttatatttcc tctataatcg aatataggaa acataactct atttctaaat ttatcatagc
     7141 aattagttcc atctctattt tttgcaatta gaccgcactc caataagtct tgttttttat
     7201 atcctttact gattagagta ttcataagtg aattccatga atccaaagaa aatcctaaac
     7261 caaatttctt aataatttta tcatctagtc ctcttattct taaatattca tacccaagat
     7321 ttttgcttcc caataagttt gaaagataaa atctagctgc ttccgtatga atatcttgaa
     7381 atttcttaga tttttctatt ttaatcctag tttcttcatt catgttagtg ttaatttcta
     7441 taccgcattt atttgctaaa atttttacag catccataaa atccaaattt tccattttca
     7501 tgacaaaatt tattacgtct ccaccttcac cacaaccaaa acacttataa atctgttttg
     7561 atgtatttat ataaaaagaa ggtgtctttt cgccatgaaa tggacataat cctttgtaat
     7621 tagctccaga ttgttttata ttcatatatt cagatattat acttgctata tcgcatctag
     7681 cttttatttc ttcaataatg tcttttatat cattcatatt atcaccttct ggtgtaattt
     7741 tttgtgttaa catttctatt ctacactata ttctaaattt gtcaatcact caatatacac
     7801 aattcgactt tttttattga tatccttctt attaatcaaa aaatttttat tttttatatt
     7861 aattctatca atattaaatc tttatttata ttaaataatc taactatcaa attataactt
     7921 ataaatttac cttagcaacg attacgaata aaaaagaggc tcttgcctct tttaataatt
     7981 attaattgat ttcattaaat cttcaaattc attaaagcaa agagattgag caccatctga
     8041 caaagcattt tctgggtcag gatgtacttc taccattatt ccatctgctc cacatgcaaa
     8101 agatgccagt gacataggtt ttaccaaata tctaactcca gtggcatggc ttgggtctac
     8161 cacaacagga agacctgttt ccttttgaat aatgggtacc gcagctaaat ctaatgtatt
     8221 tctagtataa tcattatacg ttcttatacc tctctcacac attataatat tactatttcc
     8281 ttctattgct atatattcag aagcacctat ccattcagta attgtggatg ctattcctct
     8341 ttttaacata acaggtttat tttgttttcc cacttcactt aaaagagtaa agttttgcat
     8401 atttcttgac ccaatttgaa ttatatcact tatactatac agttcgtcca tatctcttac
     8461 atccataagt tctgtaataa cagccatacc aacttcatct ttaaccgctt ttaatatttc
     8521 aagaccttct ttttttaatc cttgaaatga atttggagat gttcttggct tgtatgctcc
     8581 acctcttaaa atatttgctc cctgactttt tacaaattta gcagtctcca aaagttgctc
     8641 ataactctct attgcacatg gtccagctat tataagttta tcttttttta cagttatctt
     8701 tttgttattt gtatttatct ctatctttga attattatta aataggtttt ctttcataac
     8761 ctacaagctc ctttacttct tctctttctt cagcagatag gaggtttaaa tgttctttta
     8821 ttgttttttc atttattata agttcttcat ttaaatccat aagtggtatc aaaacgaaag
     8881 ctctatcttg aatccttgga tgaggtattg ttagtctttc atcagtggaa actacatcat
     8941 taaaaaatag tacgtctaca tctatagttc ttggtcccca atgaactatt ctctctctat
     9001 gtagttctct ctctatttct tgacaatatt ctaacaactc ataaggttca aactctgttt
     9061 ctatttctac acacatattt agaaaatctg cttgttctgt atatccccat ggttttgttt
     9121 cgtataagct tgattctttt actttatata tagaatcact atttttcaaa agttcacatg
     9181 ctcttgataa attatcaaat ctatcaccca tgttagtacc tattcccaaa taagccttat
     9241 tcatctcttg ctctccttat ctcaacacca aaatagtcat aaataccatt tacaggagcc
     9301 tcaggctttc taactctgac cataactcca tttataagta taaatttatt caagacttct
     9361 tcagcaatat tttccgctaa agcctccaaa agattaaatt gtttattttc agtaatatct
     9421 ttaacaacat tgtaaacctc ggcatagctt acagatttat ttatatcgtc actaagacct
     9481 gcttctcttg aatcaatata aagttccatg tcgacaaaga atttctgacc tagaaaattt
     9541 tcttctttaa gaacaccatg atatccatag aatcctagat tactaagtaa tattttatcc
     9601 attatattat acctactttc tatatattgc atcagtcatt ctagctgcca ttaaattttc
     9661 ataaacatca tgtactctaa ctatatctac gccatctctt ataccaagaa cagtagtagc
     9721 tattgtacct tctaatcttt ttttaggctc aactggaagt acttttccta ttactgattt
     9781 tctggatgtc ccaagcaaaa taggataccc taaatctttt aattcattta atcttctcaa
     9841 tacttcaata ttttgttcaa aatccttgcc aaatcctaca cctgggtcaa gtactatttt
     9901 ttcttttttt acaccacaac tcatggccat ttctatactt accttaaaaa agtcttttat
     9961 tgactccatt atatctttgt catagtttgt cccatcttga ttatgcatta tacacacttc
    10021 tgcatcatat tttcctatta cagaagccat atttttatct tttctaagac cccaaacatc
    10081 atttaccata gtgacaccta attttaatgc ttcttctgca acatctgcct tataagtgtc
    10141 tattgatatt ggtatatcca attcctgttt aagttttttt attacaggga ttactcttct
    10201 tagctcttcg tctgagtcta catagctatg acctgggcgt gtagactctc ctcctaggtc
    10261 tattatatct gcaccttggt caaccatatc ttttgcatgt tgtattgcta tgtccaagtt
    10321 attaaaatct cctccatcag aaaaactatc tggagttaca tttaatattc ccattatata
    10381 agttctttta ccataatcaa acacaattaa tgacactccc ttaaattaaa ttttatctca
    10441 ataaatgatt atatctataa taaattgcta cttcatagta atcaaactca tagcctcggc
    10501 tctagatgca atgtcctttt caaatattcc tctcactgct gatgtaacag tttttgaacc
    10561 tggttttttt acgcctctca ttgtcatgca catatgttca gcttctacta ctactaagac
    10621 accataaggt tgtaattctt ccattattat atctgcagca tttttagtga ttctttcttg
    10681 taattgtggt ctttttgcca atgtatctat tactctagca agtttagaaa gccctgtaag
    10741 tcttcctcct tttggtaaat aagcaatatg agcttttcca aagaaaggaa ctagatgatg
    10801 ctcacaacat gaataaaatg gaatatcttt taccaatact aactcttcat gtttttcatc
    10861 tgcaaaaaga acttttaaat ggtctcttgg ttcttcacta agaccagaga atatctcttc
    10921 atacatccta gcaactctat ttggagtttc gattagacct tctctatctg ggtcttcccc
    10981 aattgcctct agtatttctc ttactgcatg ttgtatcttt tctttatcaa ctttattcat
    11041 ttaaactccc cccattgatt tgtgactaga agattagttt tataacctct tttgtctcaa
    11101 tttctttaaa aatataatta taaacatcta aaagtctttg atagtcataa ttttcactta
    11161 cttttgacac tagttcaaaa agctcattat tttctttttt taaaactttt agcaattttt
    11221 tgtcttttgg tacccattta tcatttatat taaagtaccc aattattata tcttttaaat
    11281 ataaattcgt caaaaaatga tattcaaaaa catcaaattt ttctttattt tttaaattcg
    11341 atatttttgt tccaatatct tgctttataa aagacttttc ctctaatgac attttactag
    11401 gtccttctaa gtaaatatct ctacttatat cttttataat atgtgatata ttctccctat
    11461 caaacagtac tttagcatct ttcatttctt tcacaaagaa atattcccta tttgataata
    11521 atttttttac accatctttt gaaaagtaat ttacatcaaa ttctattccc ttttttttaa
    11581 acagtattct ctcttgtttt tccccttctt ttacaaaaac gaacacatca atatcgttta
    11641 tctctacatc ataaagagta aaatctacgt ctttactaga acccactaaa tatacagcca
    11701 aagtgttttg gttttctatt attttagtta tctcttcatt gtatacttca taaatacaac
    11761 ctatcatctt ttgtctccaa caaattgtta atattttaat ttattctaat aacttcacta
    11821 ttttatcaaa aacaacattt tctttattaa attttatttt gtcaatttct gtaaccttta
    11881 tagcgcccat aagactattt gtgacaaaaa caaaatcaaa actactaatt tctgatatat
    11941 taatttcatt ttctatcaac tctatatgta attcgtcaca aatctctata atcctttttt
    12001 ttattattcc atttaatatc ggtaatctat cactaggagt gtacactctt tctcctttta
    12061 taaagaaaat attgctcata gaacattcta atattacacc ttctgaattt aaaaatatac
    12121 catcattata accagtctta tttgcgatat ttttggtata tatgttttca aaataattag
    12181 tagtcttatg tctatgaatt aaactattcc ccctaactat tggagatata gctaatttaa
    12241 accccttctc atacgtctct tgattatatg gaatatccct aatagatata ttataacctt
    12301 catcaaaaac agtaattcta agtgctttat taatgacatt ttcttttttt atatatgtaa
    12361 caatttcatt tatcaagaaa tcttttttat agtttatatc taaatccaaa caatttattg
    12421 agcttagcat tctttctata tggatatcta aatctactgc tattccattt ttaactctaa
    12481 tagtttcaaa caaaccaatt ccaaatttac ttaaactact atcaaaacct acattattct
    12541 tcataatatc ccctcaaagc cttcattatg gatttagctt tatcaagtgt ttcttgatat
    12601 tcttcatctg ggtcagaatc ccaagtcatt cctcctccaa cttgaaagta gacttttttg
    12661 tcatttttga ttattgttct aattgctata ttaaaatcca tatcaccatt aaaacctata
    12721 taacctattg aaccagtata tacatttctt tgcgttggct ctaattcgtc tataatttcc
    12781 attgctctaa tcttaggtgc tcctgttata gacccccctg gaaaagttgc ttttattaca
    12841 tcagtagcat ctttatcatc ttttaactca cctacaactg tggaaactaa gtgatttaca
    12901 tttgcatatg gttcaattac aaatagctct ggaactttaa cacttccagt tttagatatt
    12961 ctcccaatat catttctttc taaatctact atcataagta gttcagctct atctttttca
    13021 ctatttctaa gttcttgttg aagtcttaaa tcttcttctt tatctttccc tcttggacga
    13081 gtacctttta ttggtctagt ttctattctc ttattaacac atcttataaa tctttctgga
    13141 gaatttgata atatatgtgc atcttcaaag tttaagaatg ccccaaatgg tgctgggcta
    13201 aatcttctta agtccctata caattcaaag cttgtaagtt ctgtttctcc actgaacctt
    13261 tgtgttaaat tggcttgata tatatctcct tgtcttatgt actctctaac actttgaact
    13321 gcatttttaa attcttcctt tgtaaaatta gacttaagtc ttataggtgt tacttctttt
    13381 tcttcataac atatgctatc tatacctttt ttctcttctt ttaatattct ttgttctata
    13441 tcatctatta tcttttcttc taattcgata tctatgtttg gagtagctat ataagttttt
    13501 tgcacaagat ggtctataac tattacatga ttataaaatc caaaatacat atcaggcatc
    13561 tcaatatcat ctacagcagt tctaggtaaa ttttctatgt aattacctaa atcataagat
    13621 aaatatccca cagcacctcc tacaaatgga agattagtat catttacaac cctatactta
    13681 tgtagttctt cttttaaaac ttctaaagga ttttcatcag tatctttata ctttaatacc
    13741 ttaaatggtt ggctacttat aaaagaatat cttcccaatt tttctttatc catagcactg
    13801 tctaatataa aactgtcatg ttcatttcta aaaatagtaa atatctcaaa agaatttaat
    13861 ttagtattta tctctcttat catattacat atgtaccctt tctctagctt ctgttataaa
    13921 atttttaagc atttcatgac catactctga caaaatagct tctggatgaa actgtactcc
    13981 ttctattaaa tatttcttat gcctaatccc cattatttcc cctttatcag taattgctgt
    14041 aatttctaat tcttttggaa ctgtattgga gtcaactatt agtgaatgat acctagtgac
    14101 atttaaagga tttttaagtc ccctaaaaac tcctttatta gtatggttga tactatatac
    14161 ttttccatgc acaggctgtt gtgcttttat aatatctcct ccaaaaacat gtccaatagt
    14221 ttggtgacct aaacaaattc ctagtatagg ttttttcccc ttaaaatgct caacaatatc
    14281 tatgcaaata ccagcttctt ttggagaaca cggtcctgga gataacacaa ttacctctgg
    14341 atttagttct tcaatgtcac ttattttgat ttcattattt ctttttacta caactgtttc
    14401 tcctaattct tctatatatt ggactaggtt gtatacaaaa gaatcataat tgtctatcat
    14461 aagaatcata ctgtaaatct ccccctaaaa attattttat caactcagaa actgttacaa
    14521 atttaaaacc tttttcaatc atttttggaa taaacatatc taaagcttca actgtatcat
    14581 tagttgcata atcatgcaaa agtattatat ctccattttg tactttatta attattttat
    14641 ctgcaatgct attagctcct ggatttttcc aatctttcac atctacacct gtccataaaa
    14701 caactttata gtcatgcttt tttgcaattt ctattaattc tttttctcta taacttccaa
    14761 atggtggtct aaataatgtc ggtttttttc cagttacttc tttcaaaatg tcttcacact
    14821 taacaatctc ctcttctatc tgactagaac ttaaattact tatatcagga tgattgaaag
    14881 tatgatttcc tatctcgtga ccttctttac ttgctcttac taatggttct ttataccatt
    14941 ttgcatgttt tccagctata aaaaaagtag cttttacatt gtatttcttt aatacatcta
    15001 aaacttgact agtttcttta ggatgaggac catcatcaaa ggtaattgct attagctttt
    15061 tttcccttga accatgttta atcaaaacat ttccattagt atccatcatc aaagcagaaa
    15121 ctttactaaa attagatatt aacactattc cacaaaacaa gactactgct attaagcact
    15181 tatatactgt cttttttttc catgatgtca ttttttaact tcctttcaaa tattttagtt
    15241 atttataaaa attttgagtg taatatgttt tatagcttcc tccaaatatt actccaactc
    15301 caatattatt atagttcccc aaaatatttt ttctatgtcc ttcagagttc atccaagctt
    15361 catgcgcata tattgcatta atctgtcctg ctgctatgtt ttctccagct gaagtatata
    15421 ctataccttc tcttttcatt ctgtcaaatg gagtttcatt cttcttattt acatggtcaa
    15481 aaaaattatt atctctcata tcttcactat gttttcttga actcaaagtt gcctgttcac
    15541 tgtatctcaa tgagtttaac cctctttgat ttctaacact atttacaagg tctataactt
    15601 caagttcaaa acatttttta agttcttcgc tatcatctgg atataaattt ttaaactcat
    15661 cttcagtgct tttatcaatt attaagtatg aacaaactct attttcttca tgaatatcgt
    15721 agaaaattgt aatatactta ccttccttac ttattatatc atattgattt tctgagttta
    15781 ttatatatct ggtatttcct tttctcttat attttaatgg tgtaatctta gttcttactg
    15841 tttgtctatc ttgatttagt tttatatctt gattttcaca tgaattaata gaattactat
    15901 aaagtgctac tacttcatca ttttcaagtc caaccattgc aaattctttt ccatattgat
    15961 tatatacata ccaatcaaaa ccatattcac taatatcaat tctaccaggt ttgccgatac
    16021 ttgataaaac atagcttaaa ttatctccta agcttatttt ttcaaaattc tttatatctg
    16081 actctcctaa gttctcccct tcagtattat ttgattgtaa attttgactt ttttcttttt
    16141 tatctttctt agaattatca tttatattta ttttgtctaa aaattcattc catatttcac
    16201 tttgaaaaaa cttttctttt aaatcatatc cttcttttaa taattcagga ctataaaata
    16261 aaacaataag tactactaac actaaagcaa ttaatctctt caatatatct ctccttctta
    16321 aaatcaatca aaatttttta atattgcatt tattaagtta atattgatag tgtatactaa
    16381 tcaatatcat tcatacctat ttacagtaag tattagaaaa aagctttatc tactaattag
    16441 ataaagctac agtctcaagg aaaatatttc atctaatgtt ctatcaaata tagatggctt
    16501 atcaaatttc caagtccctt cataaaccaa ttcattattt agataaaaag ttccttgccc
    16561 atgtttttta ccatgcataa attcacctat atacttttta cctttttccc atatataagt
    16621 tcccttacca tgaatcaaat tattcttcca ttctccttca taaagtactt cccctttact
    16681 attatagcaa ataccgtacc cttccatctt tccaccttta aattcacctg catatataca
    16741 tccatcactc cacttataaa taccttttcc atcttttttt ccgtttttcc aagttccaat
    16801 atattcatct ttactactat ataacatatt tccaataccg ctcatcatat cttcctcaaa
    16861 ataacctata tattcatttc catttgaaaa tataaagttt ccttttccat tttttttatc
    16921 ttctttaaat tctcctatgt actccataac tgttccttca tctacaaaaa aagtatatga
    16981 gcctttcccc tccatctttc cctctaagaa tttccctaca tatacatccc catttgaaaa
    17041 tttatagatt ttattttttg gtttttttgt atcgacatca tctatatcgc gtattgtttt
    17101 tccttccaat tctaatactt cattttccgg agcaaaatcg ccccttttta aaacacgttt
    17161 cttcatgttc tttatacttc taatctcttt gtttacttca tttatatatt tcaaataatt
    17221 atcatacaaa ttaacatatt ctttagataa attcataatg ccattcctcc aacgttattc
    17281 ctagatattt tactaaatct attaaattta ttatatccta atagtggtca tgttttctac
    17341 atattaagta attttttcaa ttttaatttt aaaatgatat cttttaaagt gatacacaaa
    17401 tcattaataa aacctttatt ttcgtatact aaatttaaat aagctgagag atataatata
    17461 caaatttaca ttataaactc ccagcttgta aaattttcta taaatctttt gctttaaacc
    17521 ctcttccttt tacttctgta acatcattta cagatataaa ggccttttta tcatacttca
    17581 aagctatatc ttttatcttt ggtatctcat ttgatgaaac tattgtatat ataatcttct
    17641 ttttttgatg agtgtatgca ccttctgcat ctaaaaaagt tacacctcta actaaactct
    17701 tcattatatc ttctgctatt aaatcgactt catttgacat taccataaca gatttttggt
    17761 aattcattgc atctttaata aaactcattg aatacgcatt tagaaataga cctataagag
    17821 tgtataatgc taaatccaac ccaaataaaa aacttcctgt aagtactatc aagccattta
    17881 ttgctaaagc agtgtctttc atttctatat tcttcttaat ttttagtatt gcagctatta
    17941 tatctgtacc accttgagaa gacctagttc taaatacaac tccgactcct aaaccagata
    18001 atataccacc atatacactt tgaagcaata tatcatgtat aggtataata ttacttattt
    18061 cctgagttgc tcctaataat aatgaaaata caatcatatt taccaaactt gaaatacaaa
    18121 actctttttc aaggtatatg aaccctaaga taaatattgg aatattgatt aaaaatgtta
    18181 ataaacctac atttatattt gtcaaatagt ttatagatgt tgctatacct gtagcacctc
    18241 cactaagtag atgtgctggt cttaagaacc catttattcc tatagatgtc atcaacatcc
    18301 caaatagcat tgttgaatat cttaaaactg gatgtttttg tagggtattc ttaacttcac
    18361 tcatttcttt ctcccttcaa tctttctaaa tctttagaat tttaaaagct tactcttaca
    18421 tatattattc ctgatgtaat agataatatt tcaaataaat tttttttata atttcttgaa
    18481 ctgtcatcta ttacatcatc tattatatta tctttttcat atatgtctag tgcaatcttt
    18541 tatattctaa tctttaaaaa cgttcaaatc atctcattta tgccttaaat gaaacttttt
    18601 ctagcataat atgatactgc ttattattta acttgcaata tagtaaattt atagtatttt
    18661 tttctaaata tctattttcg cagtaattta ttttatttta gcaaattcaa gtttagtaat
    18721 tgtctcttta taattaattc ctaaatgaaa tttttctttt tataatttca gtacatgatt
    18781 tttttatttc attatttgca tttttttcgt tcagttttta ttttaaattt tttttatttt
    18841 attttgtttt aagtattcaa ggtactcgtc ttaattttat tttttatata aaattcatta
    18901 taattggaat tagtattact gtaattgtac cagagactcc aatagaaaca ccactcatag
    18961 ctccttctat ttctccaagt tcaaaagcct ttgtagttcc taaagcatgt gcagatgttc
    19021 caagagcaat tcctttagca actggatgat ttatattccc cagtttgaat actgtagaag
    19081 caaccatacc accaaaaata cctgtaaaaa ttatggctac aactgttatt gattctatac
    19141 catttaaaga atttgctaaa gatattccca ttggtgttgt tatagatttt ggaattagtg
    19201 aatttattat acttacatct gaattagcta ttttgccaat tatcaataca gatacaaaag
    19261 aaatcactat accacaacct attcctacaa taatctcaaa catatgcttt ttaaataatt
    19321 caaattgttt ataaagtgga actgcaagta ctactgtgac aggacctaaa aagaaattta
    19381 gactatcagc tcctatcttg taattctcat aagggatttt agatatgctt aaaaacaata
    19441 ttattcctac gattgcaatt aataaagggt tacatatagg attacttgtt tttcgttgaa
    19501 tgtatcttcc taaattgaaa aaaactattg ttactattat accaaatact ggtgtctgta
    19561 atacattata catttttttg tccttcttcc ttctttttta tcattttctc cacaataatt
    19621 ccagtagtat acattactat tagtgtactt aaacatatga ctaataaaag cactaataca
    19681 ttttccctta ttaggtctaa tgactttata agtgatacac ctgctggaat aaaaaatata
    19741 gccatattat cgaggaaaaa tccacttaca ttttctatac tactcaagtc taaaacttta
    19801 aattgtagta gtagaaataa taatagcata ccaactatac tcccaggaat aagtataatt
    19861 ccttgtataa aggaacttat atactctcct attacccaga tagataaaat tattactaat
    19921 tgattgaaaa ctttcatttt ccacctccaa aaattaaaga gattgcttca aatcatatat
    19981 ttgtagtttt atcaacaagc aaatatcttt ctttaaaata gaaagttata atttgacaca
    20041 atctcttttt aaatttattt ttattttaat ttaataaaat acatacttgg ttgtttcaaa
    20101 aaacttaact atataaacct atttttcact taaaatttct tttatttttg aattgttata
    20161 catactgtct ggaacttcac ttctcaaact ataaaaagtc tgttgtgcat tttttaaatc
    20221 gccattatca taataaagca tacccaactc gtaatatgaa tcatcataat actggtcatt
    20281 tttagtataa gtatttatat attttttgta atattttata gcttcatcct tatttcctaa
    20341 taatttattt gttattgcta attgatatat tgactcagaa atatattttt tagttttacc
    20401 agaagaaact acacttttaa aattatctat ggctttttca tattctttgt ttttctttaa
    20461 atttagagct tgataatata aatcttcctc atcagctaca gttatctctc tttctggttc
    20521 tttattttta acctcattta attccttatt cgttttttct aattttttac tcgtttctcc
    20581 taacttttta tcagtttcac ttaacttttc ctctttacta cttatttggt tattcaagtt
    20641 ttctattctc tttttgcttt gaatcaaata tatccccata cctattaaaa cacagccaac
    20701 tataatatat ggcaaaatac ttttctttct ttttactttt tttatttctt cctttttact
    20761 tgtatcttct ttttcttctt catttttttc aaatacagga ttatctttat ctagctcttt
    20821 aagtttgtct aaatatcctt ctctcttttt tacattacct agtttatcat ataacaaaga
    20881 taaaattaca tatggctcta ttagttcagg ttcttcttca attatgttct ctaaaatatg
    20941 tattgactca taatttaatt cttcatttat aaatcttata gaatgattgt atcttcctaa
    21001 aaaagtttta aaatcttcag atgaaattag atttacatat tttctagata tatgattatt
    21061 ttcataacat aaagcagtat aaaaactctc aaatgattta gcaaaatcac attttaataa
    21121 ttttaaaaga cctctaagat ttagtatatc aatgtcttta ggatttatct ccagagcttt
    21181 attaaccata ttaatggcac tagttatata atttttatat gctaaatcca atgcattgtt
    21241 atatctttta tatgattcta attttaactc cttagacgtt gtgtctgact ttgaatttaa
    21301 agctccttgc aagtttaata gagtttcttc tttataattt gtagtcacat aactctgttt
    21361 taatgctttt aatgtttcat caccgtcttc ttcttctata ttaaaaaaag tcaaatcact
    21421 tttattatct tctatcaaag atatatctaa aatttttcta ggcatgcttt ctatgtcttg
    21481 ttttatatct ttaactaaaa taatactcac ctccactcta aaatatatat ttaagataac
    21541 atatttaata tgtcaagtca aaactataca tatttttcca ccattctcat aataaaaaag
    21601 gtaatcctct tcttttcata aaaaggttac ctctttttca atactattaa cttttaatgt
    21661 tgaatttttt tacttttcta tagagtgtag ctatacctat atttaatgcc tcagctactt
    21721 ttttcatacc ttctgtatta cttccatatt tctttatggc attttctata gcttccctct
    21781 caaggtcatc tatagtctta acttcttgtt tataaagttc atctagttta aaagatatta
    21841 aatcagacat actccttaca aaagcagtta actccttatc ttttgaaagt atcttttctt
    21901 tttgttcttc attaaacgca gctataccca agattccaag tatatgctct cccattttaa
    21961 cgggagtgca tatatcagct aactctttac aattttctct atttgcacat ttattacagt
    22021 tctcttctat ttctttattt ataacatagg attttccatc ttttaaaaca agagagtaca
    22081 ctgacttctc tgatattgtc tctcctattt tacctctgaa tattcctgta cctgctatcc
    22141 tagttaaatc ttttgtaact aaagtaacat ctacatccaa gacattagaa atattctcgc
    22201 aaatactttg aacgtaattc gttatattat ttaaattcaa agtaatccct cctatttaga
    22261 tttatatttt ttattactct acataaatcc tattcttgag aactttaagc ttgcggttgt
    22321 ggttgtgtct cattaggctt attatcagtt ggtggtgttt ctggtttttg ttgattattt
    22381 ggattttgat tgtttgtatt ttgattattc ttattttcgt ctgtatttgg tttttcctct
    22441 ggttttggtt ccatagtccc aactaatata ataccttcct tcttaggata atatgaatta
    22501 gctatttttt cagttttaat ttttttacca tttgcatcat taaatgttct atatgttgat
    22561 acagaatatg catttcttcc acttttgtct actttttctt tacctttagg cattgtaggg
    22621 tcattaactc ttttcattgt agtttgtgaa acgccatcta attttgttga tattgttata
    22681 ttttgtttat cttctgcact tccatatata ttgcaaacaa tttgatttcc tgaaacgtaa
    22741 ttttttatgt aaactggatg ctttagatta tttttaaata agaaatctat tccactatct
    22801 gcaacagttg catctcttcc ttttggaaca taacttgatg gtatagtatg attttttaca
    22861 ttaacaattt ctaaacctgc gtataacaca gaattgtata acgtagatga aacttgacaa
    22921 actcctccac cataatcttc ttccatctca ccttccatta ttacaggtgc acttttatat
    22981 ccattttcct tacttctttt ccctgtatgt ttattaaatg agaaagtttc tcctggcata
    23041 agtaatacat tacttatatt atctgttgct aattttatgt ttatacttct atttatttga
    23101 gaagttttaa atgttgttga atacgtacct aaatttgtat ctatattagc aagttgctct
    23161 ttttttactt ttgctggagt agcttttact actaactcat ttttatagtt acctttttta
    23221 gtttgattat caaaattctc catactctta gaaatatcca ttttaagacc atcagaatct
    23281 ggtataacct tgactttttc accacttata tcaagtgtag catcttttac atctacatct
    23341 atttctttag ctatcttttc catttctgct tttaatttat ttttatcata atttatcaca
    23401 actactaagt tgcttttttt gccaaaattt gctgaaatag tttttgatag attgccaaag
    23461 aaagcactct ttctatttaa attatatgcg ttttctactg ttttatccag gtcagtagat
    23521 aaatttaaat ctttgctctt tactttccaa cttttatcat tgtaattaaa atcaacattc
    23581 tctaatttgt attttttagc taattcctgt tttgcttgtg atttagttaa ttttccaata
    23641 tttactccat taacatatgt gttttttgct attttctccc ctttaaattg catgcacatt
    23701 atgcctataa aaattattac tactaatgct acagctccaa tagctataac tagctttttg
    23761 ttcacattac tcatcccata cttctcctta caataaaatt atttatatat ccctattatt
    23821 atattactac ataatgcgcc ttaaaacccc aaaaactttt taattatata ttaatttaat
    23881 attattaata ttcatttagt ccattttctg atatggcata tattttttca ttgtaaatat
    23941 taatagcata aacttctttg cctctaaata agcctttatt tactacagca taataataaa
    24001 tatttttata ttttccaaac aattcttcta aactcttttt actttttaca tatctatctg
    24061 ctttctctat atctaatatc tcaatctttt tatacttatt ttctttttca tcgagagtat
    24121 tagttaacac aaacttagct ttatcttttg taataccaaa ttgataactt ccatcttcta
    24181 atattctaaa gtatccatca ccataatcta ctttgtaatc ttttttacca tctttatatg
    24241 aatataaatc tttagttttt gcacttacca aaacttcatt tattaattta tcatactcat
    24301 atacttcagc ataatagtat ttattatttt ttatcatttg tggaagtgaa tttatagata
    24361 gatttgcctt gtctttgcca ctttttttag ctattacatt tataatgtca tcagatgtta
    24421 aagtatacaa tgataaattc tttttatatt ttttttctaa actctgtacc ttttcatcat
    24481 ctgaataatc gtcttttaaa tactcaatat attgtaatgc tctttcataa tctccagaag
    24541 tatttgcctc ttcagctcta cttatatagt aatcatacat ttcttcaata cattgttctt
    24601 tcccattttg agccatactg taatactttt catcttcttt taatacttta ttatactttt
    24661 caatagcttc ataatactta tatgcttttt ggtcttttac tgctgagtca taaacatctc
    24721 tagactcttt gattgtttct atattctgtt tgtatacatc taggttacta cccataccat
    24781 ttaatattga aacagtactt atgtagttaa tggcaatatc ataagtagta ttttcttctt
    24841 tatacatttc tctaactcta tcagcttgaa ctaataagtc atccacatct atacttattt
    24901 tgtttaattc tttcacggta tttattaatc caataaaact ttcttgactt atgtctccat
    24961 ctaaatattt atcaccacta tttaatagca atttatttat ttttttagaa acagacttat
    25021 taaacctttc catttttgaa tcagaaaact ttttttctat acttgtgtag taatcaacag
    25081 ctatagaata ctgtcttttc tctataatct ttaacaactc attagcttca tttcctacac
    25141 taaactcgtt actacttaag aaaaatacta ttatcaaagc aattacacct aatgttgata
    25201 atgaaatcgc aactatagat ttcctttttt catcaataaa atctacagcc ttctcaaata
    25261 aatctctaaa atacattata gttccctctc catttaataa tctttatatt ttatggtaaa
    25321 ctaaatttct tattggttat tatatcataa ttcttgaaaa aaaataaaaa cacaagttaa
    25381 atcgtgtttt tattttacct atcaatcatt attttataca taaatatttc ctttacataa
    25441 attatgatat ctttcttttt atatccctag aatgactctt ttgtttttta ttagtactga
    25501 cagttttcgt tcttgtcttg tgtatagctt tgctatcaaa tatttttcta gcattgcata
    25561 aaacaattcc aattgttaaa caaactgtaa gcacacttcc catcaaaaag taataatcca
    25621 atcctatatg tactcccata actgaattta ttaacactaa tgcaaaagtc attgcaaaac
    25681 atatcatcat ggagataact aaaattctta gaattttttt caatccactc acctcgtata
    25741 atcactaaaa ttgacactac cccttatcca ttactatacc aaattagtaa aaaaatagca
    25801 attactattg tcatttatat taggaaaata ttaaatcttt ttaataaata tctttttttg
    25861 acataaggat tacttaactt ttaataaaat agtaacacta atatgtatta attaatagaa
    25921 taaaataaat gataatttat tgaggggtga tttacatgcc aaatttgcca agtttagggt
    25981 caaaggctcc tgattttaaa gccaatacaa caaatggtcc tattagactc tctgactata
    26041 agggtaattg gattgtttta ttttcacatc ctggtgattt tacaccagtt tgtactacag
    26101 aatttttatg ttttgctaaa tattatgacg aatttaaaaa aagaaataca gaactaattg
    26161 gtctaagtgt tgatagtaac agttcacatt tagcttggat gtataatatt tctttactta
    26221 caggtgtaga aattccattt cctattatag aagatagaga tatgagaatt gccaagttat
    26281 acggcatgat atcaaaacca atgagtgata catcaactgt tcgctctgta tttattatag
    26341 ataataatca aattctaaga acgattcttt attatccact aactacagga agaaatattc
    26401 cagaaatact tagaatagta gatgcacttc agactagtga tagagataat atagttactc
    26461 ctgcaaactg gtttcctgga atgccagtga ttttacctta tcctaaaaac tataaggaat
    26521 taaaaaatag agttaacagt tgtaataaga aatattcatg tatggactgg tacttatgtt
    26581 ttgtaccaga taattataat gatgaagaag tgagcaagaa aattgataat acttgtagct
    26641 ggaaaaaaga acatactaaa aacattgaaa atgaatgtaa ctgtgaacat gaacatcatg
    26701 actacctgaa caaagctctt gattgtaaac aagaacacaa gactgatatt aaagatgatt
    26761 gcaaccatga gaaaaaacat actaaaaata ctaacaaagt tcacaactcc aaacaagata
    26821 agtttaaaga taagtcttgt gatgaaatga attttaacta tgataaagat gaatcttgcg
    26881 acaaaataaa ttctagctat gataaagaag atagtagtta tgaagatttc tataaacata
    26941 attataaaaa ctacgattat actagcgaaa aaaatactaa aaaaatagct atgaaaactt
    27001 taaaagattc aaaaaaatta gttagaccac aaataacaga cccatacaat ccaatagttg
    27061 aaaatgcaaa ctgtccagat ataaatccaa ttgtagcaga atatgttctt ggaaatccaa
    27121 ctaatgtaga tgctcaacta ttagatgcag ttatatttgc ttttgctgag atagaccagt
    27181 ctggaaattt gtttattcct tatcctagat ttttaaatca attacttgct cttaaaggtg
    27241 aaaaacctag cttaaaagta attgtagcta ttggaggttg gggagctgaa ggattctctg
    27301 atgcagcatt aacacctaca tctagatata attttgcaag acaggtcaat cagatgataa
    27361 atgaatatgc tttagatgga atagatatag actgggaata tcctggaagt agtgcatctg
    27421 gaataacatc aagacctcaa gatagagaaa actttacact cttactaact gccataagag
    27481 atgttatagg agatgataaa tggcttagtg tagctggaac aggagataga ggatatataa
    27541 attcaagtgc tgaaatagat aaaatagctc ctataataga ttattttaat cttatgagtt
    27601 atgattttac agcaggtgaa acaggcccaa atggtagaaa acatcaagca aatctttttg
    27661 attcagactt atctttgcca ggatatagtg ttgatgcaat ggtaagaaat cttgagaatg
    27721 ctggaatgcc ttctgaaaaa atccttcttg gtataccatt ttatggaaga ttaggtgcta
    27781 ctataacaag aacttatgat gagcttagaa gggattatat aaataaaaat ggatatgaat
    27841 atagatttga taatactgct caagttccat atttagttaa ggatggagat tttgcaatgt
    27901 catatgatga tgctttatca atattcttaa aaactcaata tgttcttaga aattgtctag
    27961 gtggtgtatt ctcatggaca tcaacttatg accaagcaaa tatactggct agaaccatgt
    28021 ctattggtat aaatgaccct gaagtattaa aagaagaact tgaaggtatt tatgggcaat
    28081 tctaatagaa tgtaggaaaa ttttatagtt atataaaaag cagattttat tatattaaat
    28141 aagttgtatc taattaatac tattattaat tgtttataaa ttagatactt attttttcat
    28201 aatacaatct gcttttttaa tcaaaattta tttaattata agttgtttaa ttacaagttg
    28261 tttaattata aagtaggaat ttagatatac tcttatacca tgtaattatg tataaatatt
    28321 tttttattat acaccaatag cttttttagc taatttatca gcttcctcat tatacttatt
    28381 tccagaatga gctttaacct ttgtaaattt tacattaagc ttattcttaa tactgtcata
    28441 gaaattttta tatgctatag ttccttcttt atttgttttc caaactccag tacaccactt
    28501 ttcaatccct tcatagtcaa agtataaaat caagttttga acattattgt caatacagta
    28561 ctgcattgca attttagaag cctctatctc tccagctaca tttctcatac ttactaaagt
    28621 tttctctttt cctttttcac tataagtttt tataacttca ttatttttta aaatcacaac
    28681 acccgaacca tacattttta ctgaatgttc ataacttcca tctacatatg cttctataaa
    28741 ctccttatct tcttgaaaac tcaatttttc tgacccatca atatattctt tagcttcttg
    28801 aaaagtagaa aaactcttat attcagctcc tgagaatcca tttacttgtt ttttgcactc
    28861 atcccatgta ttatatacac ctatattttt accttttttc acagcataaa acttttgttt
    28921 tgccaaatat atcactccca ctcttaattt ttatcttctt ctctcataaa tatatctaaa
    28981 tttataagat agtttctatc aaaatatttt actttcatat ctttttttat aatatcaata
    29041 tggtacactt ctccttttac agctctttgt cttatatttt catttatatc tttttttata
    29101 atatccttat caacatcatt gttatccatt ttagcatcaa cattcaacgc ttttatagta
    29161 tcaaatataa cagattttag tattaaactt ctagatttat ttaaatgtcg ccttatataa
    29221 gtataaaact cattgctatt aacctttgaa attttacaat cgtgtaaatc tttctctaat
    29281 ctctttaaaa cacttatatt agttcctaca tcaaaaatca caaaacatcc atagtcatat
    29341 ttgcttctta aaattctccc catagcttgc tttaccttta tggtcatttg aggataattt
    29401 atagtatagt agtctatacc atacttcttc attatagtaa aatacaaagg gtcttttgga
    29461 tttagattcg gaagcttgtc taaagttaca caaaccaaac catcccctgg aatgtctacg
    29521 ccttcaaaac atccttttga gccaagtact acacattttc tatttaaatc attaaggtgt
    29581 ctaatgccct ttttatcagc ataaatttct aagttaaaac tatgtaagta ttttttcaat
    29641 atttcataag ttttttcttg tctatcttta ctattaaaaa gagctaatgt atgaccttct
    29701 gtaatctttg atatattaga tataatttta ctcatctcat ttggaaattc agaatttctg
    29761 tactcacaaa tatcagaaaa tccaactaca gagactctat ttttataatc aaaaattggt
    29821 tctataatct tttccacatt cttaactctg tctattccta atgtattttt aaaataagac
    29881 atactttcag ataaactcaa agttgctgat aaaaatattc ctttttctaa ttgagataaa
    29941 atattttctt caaataaatc tgctattttt aatggcacta ctcgaaattc aaagtcatta
    30001 taattcttat caatttcaac tatccttgca taatcatcct tttcatcata ctctaaaaag
    30061 atttcaaata taatctttat atcctctaaa tctcttgtct ttgcctttcc aaatttatat
    30121 atatctgctt ctttatctat actatcatca tcaatattcc tataaattat tattattatt
    30181 gaaactaaat tttttattat tttctcacaa ctcaacttta tcttttcact ataggctcta
    30241 taacttattt cagtatctat accacccttt tttagttttc ccacaatttc atctatttgc
    30301 aaattcagtt cccatcttaa attataatta cttacattat tatattcatt acaattacca
    30361 aaatttaata ttgaatctat ctcttcaata atgagattta tgcttctagc aattttttgt
    30421 ttatcttctc ttccaatttt taatacatta taaaatttat caaaagcctt tatttttctc
    30481 atatttctac tatatttttt atatataaag ctactatttt gaataaactc gtaaggataa
    30541 atttcttgta ataaatacct taaagacttt gaatttataa tgcttgaaaa gaaatcatat
    30601 cctttttcag tcaaattatg tgcttcatct actattatat tttctaaagg tttttcatcc
    30661 ttatacggcc atttagctaa tagtgaatga tttactactg ttatatgttc ttcttttaat
    30721 tcttctattc tgtttttata taaacaatct tttttgcatt ttttaggtct gcacatattt
    30781 gggtcacaac ttacatttct taagtgagta cttatttcct tgaagttgtc aaacactaaa
    30841 taatttattt cttctatatc tccatacttg ccaccttcaa ctaatctctt caaaaatatt
    30901 aaagataaaa tttctccttt agtagggttt tgagactcat aatcatctat atatgcttcc
    30961 agtctatcta tacaaatata gttatttttt ccctttatat atccgtaact tacttttcca
    31021 tttagaccca aagaatctaa cacatttgga atatctttat ttattaattg tatctgcaat
    31081 tcctttgtgt cagtagaaat taataatctt tttttattaa ttctagcctc taatattgca
    31141 ggcaataaat atcctacact tttacctata ccagttggtg cctctataca tgcaattttt
    31201 tcttcatctt cgctatttct aaacaactct cttattgttt tagtaagctc atattgacca
    31261 ggtctatatt catatgtaaa tccttcttta ttctcccaaa tagttttgta ttttaataat
    31321 tcttcataat ttttttcttc ttcatttaaa atttttaagg tttctctttc cttcttcttt
    31381 tcttcttttg agtcaaatat attatattct ttttttatat ttatattatt tgataaatca
    31441 taatttgcct cttctaaaaa tttgctccat tcccatgttg gaagattaaa ttttttaaga
    31501 tatgaattta ttttaaaact caatggctcc aaagtagttt tttcatagtt attaaatttt
    31561 actaaaaggc aatttacaat atttattata tcaatagcat ctgataaagc tctattttcc
    31621 actttagaat tacaatttgt taaagtattt tttaagtatt ctaagctata atctttatga
    31681 tatggttcta aaataactgc taattcaatt aaatcaataa atttgttttt taactttggc
    31741 atatgatact caaaaaactt ttttttcaga cttaaatcat gacatataat gaaactatct
    31801 tctacaaaat ttacaagtct atcttccacc agttctattt cattagctat ttctaaatca
    31861 tttttatcta aatttttaca tactgagaat acttctacag gtacctcaaa tttgtttttt
    31921 attaatgatt cataggtata tattttccag tctttaacct tgacagctcc aacttctaaa
    31981 atttctgaat ttaaacaatc taatccacta acttctatat ctaaaaaaac aacatcattc
    32041 aatacactta ttatattatc catttttata tcccttcaag ttaaaccagc ctaacttatt
    32101 tacaatcatt tctctttata ttttatcatt tatatacact ttatttaaga taattaatat
    32161 caactttata tcttacagta aacttctttc atttattatt tgtatatgtg aatattttta
    32221 actataaata ttcaaactat attataagaa atatatttta aattttaaat aagaggtgaa
    32281 attgtgaaaa aagatagcct aaaaaaatac attatgatag gagcatttgc tctaatactt
    32341 tttggaattg ctagtataaa ttttaaatca ttagataaaa caaaaactca aatttctagt
    32401 ccaacactcg acacacatga atatgattgg tattttaacc ctagggagga tggtaaacag
    32461 ccatcaccta taaaagaagc tgattttttt aaaaaatacg gagcttatta tgtaggaaat
    32521 cccaatgaaa aagttatata tctatcattt gatgctggat atgaaagtgg aaacactcca
    32581 aaattattag atacgcttaa aaaacacaat gctaaagctc aatttttcgt agttgaaagt
    32641 tatataaaaa gcaatccaga gttaataaag cgtatggaaa aagaaggaca tttagtttgt
    32701 aatcattcaa aaagccatcc atcaatggca ggtattacag attttgaaaa attcaaagaa
    32761 gaaattacaa gtgtagaaaa agcatacaaa gatgttactg gaaaagaaat gcctaagtat
    32821 tttagacctc caatgggtaa atttagcgaa caatctttaa aatatacaca agatttagga
    32881 tataaatcaa tattttggag ttttgcttat gtagattggt atgaaaagaa acaacctact
    32941 catgaatttg ccaaaaacaa aatttattca agaactcatc ctggtgcaat agttttactg
    33001 catccaaatt catcaacaaa tactgagata ttagatgagg ttcttacaca ttgggaaaaa
    33061 gaaggttata aacttaaaac acttgattat ttaaataata aaaaatagta tcataaattt
    33121 aaaaaaactc tatcatgaat tatagtaaaa atatagttat ttataaatac tttaattctc
    33181 gatagagttt tttatttttt atagctattt aaaaagaatt gtccattcat ttatctcttt
    33241 gtatcctata ttatgatata ttttacctgc tacatcatta ttataaaaaa gacatggaac
    33301 ttttccttct aacaacaatt ctttactcaa attgtaaacc atataacttg caagtccttt
    33361 tcccctatat cttttatctg tacttacaga gaccaccatt gccaaaaaac tagtttccat
    33421 accagttgac acagtgctaa tcatagtatc atcatttcta ataaaatatg ctcttacatt
    33481 tccctctttt aaatgaactt ttctttcttc tatgtaattt ttacttactt tatagtctga
    33541 cctatttaaa agttttccta tttcatcaat atctttttcc tgagcatttt ctattttata
    33601 ctccttcatg ttggaaaaat ctatttcttt tatttctttt aatacacaaa atttattatc
    33661 tagtttttca taaaaatctt tgtatttact tattagtcta tctattacac atttttttcc
    33721 acttatgctt tctacatcta aatcttttat atgattcttc atttctccta tattaaaatt
    33781 atttttaaaa ctataaatta taagtgttga cttatttttt aatattatag aggttatatt
    33841 tccatcttct acctgagacc atatatcttg atattgagag ctaaatccat aattctcaac
    33901 gtatccaatt atgaataaat ttaaactttc ttcatgtgat acatattgcc aaaattcttt
    33961 ttctaaagta ttatctattt ttacaatcaa gcagatatcc tccttctatg ttaataatga
    34021 tataccttat aatttatagt atcatttaaa atcattatat tctaccaaat attctaaatt
    34081 tttaaatatc tatgcaatat gttcgtattt atttttatat tctgttactg cttcactcca
    34141 agcttcttct actgaaatac ctctcttatt tgcaattttt tgtgctaatt ctattatttt
    34201 catagctttt cttgatatat tcatatatat tcctcctcta aattatcata agttatttta
    34261 aagttaaatt tctatagtca tgttatatat ttatttactt atatcttact aattatttat
    34321 gtactaaata tgaactacaa tagaagaaat ttagaactta ataaaacata aaatttatat
    34381 acagttcata tatatttgtc atatcacaag acaagtgata taatttatta tcattttact
    34441 gggggtgata tgctatgaaa ataagagctg aatatacatg tcctcttgaa attgtacatg
    34501 acataatcaa aggaaaatgg aaaactatcc ttatatttga attaagacaa tctaataaaa
    34561 cattttctga attgcaacat aatatttatg gaataaatca aaaaatgttg attcaacaat
    34621 taaaagagtt acgtgatttt gggattattg ataaaataag ttctgctgga tatccattac
    34681 atgttgaata ttttcttact aatcgtggta aaaaaatgtt aaaagcagtg gaaataatgc
    34741 aagaaatagg aatcgaatat atgcttgaac atggtcaaca agaaattcta gataataaag
    34801 gaatttgcta caataagtaa tcctatacat accaaaaagt aagtaattta cattttttac
    34861 aatagtatta taataaaaat aaataggagg tataatcatg tctatagctt taatattgat
    34921 tgatattcaa aatgattatt ttaaaaatgg aaaatgtgaa ttatttcaat cagaagaaac
    34981 tgctgaaaat gctaaaaaaa tactactgtt ttttagaaaa aacaatttac cagttattca
    35041 tatacagcat atatcaacag ataaaacagc ttcttttttt cttcctaata ctcatggttc
    35101 agaaataaat aaaattgttt ttccactaga taatgaagaa attataatta aacacacacc
    35161 agatagtttc tttgaaacag atttgcaaag tatccttgag aaaaaaaata ttactaatct
    35221 agtaatctgt ggaatgatga gccatatgtg tattgataca agtgtaagaa cagcaaagaa
    35281 acttcgatac gacataactc taataagcga tgcatgtaca acgaagaatt tatcttggaa
    35341 taatatagaa attaatgcaa atactgtaca tcaagtattc atggcatcac tacagaacag
    35401 ttttgcagat gtaaaaaaca cagataaatt tttatctaac tatcacaaat aaaaacatac
    35461 actatgttaa aagagcaagt ttgatttatt taagcttgct ctttaatcat ttaaaattag
    35521 atgctttcta tcatttttat atacataata tacgtttata cattttatat tcatatataa
    35581 ctattatata aattttaaac tttactatat tcacataaaa aatgtagtat tatagtatat
    35641 ataatattat atagaagggg gtgctagata aatgaaccat catatattga ttcaatttga
    35701 atatatagca agaatcatta ctgctggttt ctgtggggct ttaattggat atgagagaaa
    35761 gaatagacta aaagaagctg gaatacgcac tcattttata gtggcattag cttcagcact
    35821 tataatcatt gtttccaagt atggatttaa tgatatagtg ggtactccag gtattggtct
    35881 agacccagcc cgcgttgcag cacaagttgt cagtggtata ggttttttag gtgctggatt
    35941 aatatttatt agaaatcaat cagtaagtgg tcttactaca gctgctggta tatgggcaac
    36001 agccggtaca ggtcttgcca ttggctctgg attatactta gttggtattg tttcaagtat
    36061 cattattgtt attgtacaga taacacttca tagagatagg aaatggatga aactccctac
    36121 agcagagcaa gtttctctta aaatttctaa cagcactgat tccatagaat atattgaagg
    36181 taaatttaaa aaatctaata ttgaaattat aaacatgaat attaaacgcc ttgatgggga
    36241 ttggttagaa gtagttatat atactaagtt acctaaagga tataaaaaaa caaatttatt
    36301 aaaattattt agcgataatc ctcttataga aactttagaa atataatata aaaattgaag
    36361 cttaaaaata ataatatatt taatcaaggt caatatataa ataattacgg gatgagtcta
    36421 tataaaattc atcccttgtt ttttgccatt catatatatt ttttcaagat atttttgttc
    36481 atctattatc tagccaagta gctcttgtga actaaacttt ttaatacaaa aacttcaata
    36541 caaaactaaa tataactttt attaaacatt ctacatatat agtttgtttc ttgagtgaaa
    36601 aatagatttc atattgttaa gatactgtta aatatttcaa ttttctgaca agtatgttga
    36661 acaataactt atcctagtgt attattttag ttgtagaata aaactaaatc ggcaaaacta
    36721 gagaaattta gtgacgcaaa gctataggga ctaacgctta taaaataaac tatgagttat
    36781 gtcagccagt tgccaaaaag atattgttct ttttgtttta tgaaagtttt ttagggggat
    36841 agtaatatat atgtttagag atgaaatgga taaatgtaca cacatgttaa ctgcttatat
    36901 tagtagttta tatgattatt gtgattttat agatacacag ctagatgatt ttatactaga
    36961 gtacggagaa aatgtagtag aatcttgttt acatcaagtg atggtattgg taagtaagta
    37021 taattaaata gaaattgttt tctagagaac cctttttagt tttatctaca tttaaaaatg
    37081 ttattatatt aaaaaactaa tctcccctat atgcaaagtt tcttccatat aacaatttct
    37141 tcccatttat actttttcac ttatatcttt aataaaattc aacttcaaat attaatatac
    37201 ttcaaaaatt attctatttc ttatctttac accaattcct atcaatatta tcctttatat
    37261 aggttctaac tatttcgcca caatctaaac ataaatctga atatatagta gattgtactg
    37321 gaaaagtttt atttataact ttatctaatt ttccatctcc tctatatttt aatccaatag
    37381 tttcagcata tatgccacca gttgttaaaa ttcccttttc aatatttaca cttccacaat
    37441 tagaacattt cacatttata accccctaaa caattatttt ttcatgctat cttataattt
    37501 aaaatataat ttgctaccga ttttataaca cagtggcaaa tcggtggcaa atcaacattt
    37561 tttcattcta tttaccatct aatccattga aatatggcta tttagttata ggaacttgaa
    37621 tttctgttac aaactcctct acaattccag tctcatgtat atctatcttg tagatttcta
    37681 taggatcagc aattatctta taattgtttt cttctataaa tttaaacacc ttctccatat
    37741 acatcttatt attagaatta ctcccagtat aatttaaagt tacataatat ccttcatcaa
    37801 aaactatatt atatactttc tcattacttt ccagaaaaca aaatacagat ttaaactcat
    37861 taaatatacc tttattaatt gcttcagtag aaaaggcaga accaatattg ttgtttccaa
    37921 gtatattaaa tctatcttca tattctttct gaagtttttg aattaaaaaa tcgaagtctt
    37981 catccctctt tatatcagca tttaattcta aagcttttct tttttctata tatacaacct
    38041 ctatctcatc tatttttgta ttttgaatta cactttcaat tgaactcaat ctttttataa
    38101 tattttcctt atggcttata aattcagcta tttttttatc aattaaatcg agttcttcat
    38161 ttaaaatatt tttcgtagac tctatacttc tgtcatctag gtattctttt attttcttca
    38221 ttggaaagtt caagcttcta aattctttta ttaaatttaa tttccatata tctgatatat
    38281 tatacattct atatccattt atatctctaa ctggtcttag aatgcctatt tcttcataat
    38341 acattaatga atctctacct attccatata ttttagatat ctctcctatt ttatagtaat
    38401 ctttcattta tataataaac tcctccgaaa tcttattttt attttaaatc aacattatta
    38461 ctctataata ctatagtatt agaatatact aaaaaaatct ttaaaacaag gataggaaaa
    38521 taaacatcct aataattaat tattaaaata tttttatatt gtaatattag gtatagtatt
    38581 tataacttca acttttttat aaatatattt tagttttata tagttttatg tttacagcta
    38641 ttatatccat ctctatgtaa tatttttcat attaaaactg atttctatag attaatagtt
    38701 tataaattta gtaaatgaat atttattata gtctttaaca aaaaatacaa gaataaactt
    38761 aattttaata actaaaatta attatgcaaa attattaata tggtattaaa ttatgtataa
    38821 aaagttaatt atgaataaaa taattatgcc tttgaaaaat cattaaactt aaaattaatt
    38881 ataaaaaaac tctaccttac taactataca gctcacaatc tatctattta tgaaaaaata
    38941 tgatataatt gcattcaaaa aggaaatctt tcaatatact agaatttaag cattaactaa
    39001 ttttatctaa tattattact aaactaaaaa atatttgtat ttgtagcatt ggagcaaata
    39061 acttaatgta tattcatttt aaatacttat ttaaaattta gcatttaaat tatttacaaa
    39121 ttaacattta aatacttcta gcataaatac agttgtcatc aaaatttaaa gtatcttatg
    39181 gaggaatacc atgcaaaatc ataattatat aaaaatgtta aataaaaagg tagaagtatt
    39241 atctaaggaa ttagatagta gaaattttaa attaaaaacc ttaaatgaaa tagatttttt
    39301 ttctaaaata ccaaacagag aatttatgta ccaatatatt gatgactgta tttcgaaaaa
    39361 tatacatata ggaatcatgt tattaaatat cgataacttt aaattattta atgatatata
    39421 tggatatcta gtcggagaaa atttattaat tactctaact caaaacctat tgcactttat
    39481 tccagaatca aagggaatag tcgcttattt aaaaggagaa ggttttttaa ttgtacttcc
    39541 aaatgtatca aataaagagt taaataatat tggtgcaact attatagaga gcgcccgaga
    39601 attaaaaata aaacttccta atgaaaaaga aatatactcc aatgttacat ttagtatcgg
    39661 cagcactatc tggaatggtg aaccaaacat gactactttg atgcttttca accaagtata
    39721 tagtgcttta aaaaaggcta aaagtgaagg taaaaataga tacattctat ttgattttaa
    39781 agataatagt ttttacaata aattagaaaa tgataaggag ttcttatcag aaatatcaca
    39841 tgttctacaa actaaacaaa ttgaagtatt ttaccaacca ctttataata taaaaaataa
    39901 tactatagtt ggatgtgagg cacttgcaag atggagacac cctattaaag gacttcttac
    39961 tccagataaa tttattcctt tatttgaaca gtttggtctg ataacggaat tagatttgca
    40021 tttatttgaa gagaactgta aaaatataag aagatggatt gataacaatg atgtttttgt
    40081 tccaatttgt tgtaactttt ctcgtcttca tttttttaac cctaattttc caagtatgct
    40141 aaaaggtatt actgaaaagt acagcgtctc tacatcaaat tttagcattg aaataacaga
    40201 aaatatatta atagaaaata caaatacaat tattcaacaa ctagctgaac ttcgttctta
    40261 tggtttttct gtatcaatgg acgattttgg ttctggatat tcatcttttg gtatgttgca
    40321 aaatctacct tttgatataa tcaaaattga taggatattt ttatctcata atttaaatga
    40381 ttttaaaaat acaaccattt tgtactctat aataaacatt gcaagagctc ttgggatgct
    40441 tacagtatgt gaaggtgttg aaacagaaca acatgtagaa tttattaaaa gtataaattg
    40501 tgatatcgcc caaggttatt attatgcaaa acccatggag tgcaaagaat ttgaaaaatt
    40561 actatctaaa gagaataatt cagagaaaat gtttataaaa tattctgata taggaaaatc
    40621 tttaatagag aagatatttg atggattttt tattatgcaa gatatgaaaa aactaagagc
    40681 taatgtcact gaagacattc aatggtttga tttttacaac aaaactgaaa ttacatcttt
    40741 tcctaaagta atagagcatt ttgaaaaaca tattaaaggt aaaaaatttt ctattcttta
    40801 caaaagtata accccacata atactgaatc agattcatta ttaattagtg gagaagccgt
    40861 tttatcagat gaagcttctg aacatcaaaa atatagcaat ttctacttta gtgcaaattg
    40921 tataatttca gaaaataaat tactcttagc aaaattacat ttggatttaa ttaaaactgc
    40981 tggctatata aatgaatttg aatcatattc aatacctaaa atgacaaata cacatcttga
    41041 tgaaagtaat attttatcac aattttattc aatgttgcct gtaggtataa ttcgctacga
    41101 tttatttggt gatatgatta ttacttatat gaatgaagaa atgtttgata ttataggtta
    41161 tacaaaagaa cagttttttg gtgagatggg cggaaattta agagcaattg ttcatccaga
    41221 tgatttagac tttgtttata aaaaaagttt ggctatgatt gacacaaata aaattgaacc
    41281 atttttatat agattcataa aacgagatgg tcaaattgtc acagttatgt atacacaatg
    41341 taacctttct gcaattgatg gaaggtcgat tgcccagggt atgtatgtag atgtaaataa
    41401 aataaaaaat ttaacaaaaa tctagtacaa agtattttat tttggagaaa ttaatatgtt
    41461 taaagaaatt tttttaaaaa cttttccagg atttctaatt ataagagatt ctaactacag
    41521 aattatattt ataaatgata atttaaaaaa tttaattaaa agttatatgc aagataatcc
    41581 acttggaatg actaatatag aaatagctaa gaaactccct gataatattg ctaaattttt
    41641 tatggattct cacaatattc aattagattg ggaaaaaaat tatccttatg ataaaatttc
    41701 aaattggatt tttgagttta aaaaagatac tacaagctat tggaatgttt tagaatacaa
    41761 agtagatgtt gatgaaaaaa cctacataat tactatggcc aatgatataa caaaactcta
    41821 tgaagaaaat aagagaaatc ttcactactc aattactgac ccattaactg gagcatataa
    41881 tagaaaatat ttaaatgata gatttgacat atttatagga gattatattg tactaattga
    41941 cttagataat ttcaaaatga taaatgacta tgaaggtcat aatgtaggag acaagatttt
    42001 atgtgatttt gtttcacttt taaataaaga attaataaat tctacttcta ttataagatt
    42061 aggaggagat gaatttattg ttatattctc tagtgatgtt gacaaaaatt atgtttattc
    42121 acaactagaa gccttaagag aaaatttttt aaaagtattc tctaagtata agtatctttc
    42181 atttagttat ggtgttgata cagtaaaaag aaatttaaaa ctgacaatag ttgaattgga
    42241 taaaaaaatg tataaaaaca aggagaaaaa caagaaaaaa tttgataaaa atgattatta
    42301 atattgttat tttaaaataa attaaaatta tctttctttt tttaaacttg tacattagtt
    42361 tataaatatg tatctataca agatattgac attaagtact gaagcatata ttgtttcagt
    42421 tcttttttgt taaaattaac ttatttaaca aagatatcat agtttaacaa agcttttaat
    42481 ttaaatatat tgatgtataa tataattaaa atataatagc aaaaagaaag gaggaatatc
    42541 atgagcatac tcctaaaaaa agcacccaaa ttagcaaaac atattataac aagtttttat
    42601 ataaatcggg atattgatga agtattaaaa tacctttgtg aaaatgttac atggatcgga
    42661 ccaggagaac aggaatttct cacttctttt aatgaaataa aaaattattt ttatgcaggt
    42721 caagatgaaa ttccttcttg tgatataaat aacgatatat ttgaaactgt aagtgaagat
    42781 gagaatagat gtatggtatt aggaagatat actgttcgaa ctaaagaaaa tgctcaaatg
    42841 attttagagg taaatcaacg ttgtacattt gagataattg aggatagagg aaaattatta
    42901 gtaaagcaca tgcacatatc aaacccttat ggtgaaatgc aacttgatga atactttccc
    42961 actaaaattg gaactcaaag ttatgattat ttgcaaagat tactaaagga aaaaacagaa
    43021 gttattgaaa tgattacaaa taatatcaat ggtggcttaa aaggtagcaa tgatgataat
    43081 acatactcat ttttctatgt caatgaagga ttgcccaaaa tattaggata cacatatgat
    43141 gagttcatgg aaatgagtgg tggttcagca gtgggtgctg tatatccacc agacttacct
    43201 aaagcactag aagattgtga acgatgtttt gcaaaaggac ctacatattc atctgaatat
    43261 agaatccgaa aaaaagatgg aacattaatg tgggtattag attctggaat gaaatcgtta
    43321 aatagtgatg gcatagtaaa aattaatagt attattactg acataaccca actaaaaaac
    43381 atagaatctg aactaaaatt agaaagagag cgatatcgta ttgctttgca aaatattaca
    43441 gatatcatgt ttgagtatga tattgaaaac gataccctta taaaatatca acgtgtagaa
    43501 attgacaaaa aaattgaatt agaaaatttt gaaacaaaaa attactccaa actattagaa
    43561 tctggtaaaa ttattcacct tgatgatatt ggaaaactac tagaagtact tcatggaaat
    43621 cttcgtgaaa caattgagat aagacaagta aattcattaa ctaaaaatga atggagatgg
    43681 attcgtgttc aatgttcagt tatatatgat agtgaccata accctatcaa aacaataggc
    43741 gttttaaaag acataactga agataaatct aaattagaaa gcttaattaa tcaggctcaa
    43801 cgtgacccac taacacaatt atataatcaa agagtatcac aaaatcttat tgaagagtat
    43861 ctatgtagct ctgattccaa aaataatgat gctctattag ttattgatat tgatgatttt
    43921 aaaactgtaa atgatacttt tgggcattta gagggaaatg aagttttagt tgctgtatca
    43981 aaaatactat tacataacac acatgataaa gacatagttg ctcgaattgg tggagatgaa
    44041 tttacaatat ttataaaatc attaacaaag gatttaataa taaaaattac taatgatatt
    44101 ttaaatgatg caagtaaaat aaaagtaaag gacaatcata aaataacatt aagtattggt
    44161 attgccttca ctgatgattc aactaaatta tataaagatt tattttctaa agctgataaa
    44221 gctctttatc tatcaaaagc agatggcaaa aattgttata gtacatacga ataataaagc
    44281 tatttatacg accaagaatg aacctttaaa tttaatttca tagtctaaca atcaaagagt
    44341 tgaagctaat cttatagcta gtcaactagt tcctagaaaa aatttagaca atatatttat
    44401 tgatactgct catttttcta aagagcaaat ttatataaaa aattaaactt ttatatacat
    44461 acagatacta atgataaaca gttatcatta gtatcttcta tcttaaaaca aaatgataat
    44521 ttatctatat aaaaaagtgc tttgttgaca gagttcactt ttttatatag gtacagaatt
    44581 taagtataaa tacatgtttt attctataca ttttagttaa tgtaaaattt cttgattgta
    44641 ctctctaact tttcaacatt atactattta tataccactt ggttaatata aaactattat
    44701 tatagtgtcg tgtggagggc ggtgtgactt atttacatac cacttagtta atataaaacg
    44761 aaggtgttga atttactgtt gaaaaaactt ttgatgaatt tacataccac ttagttaata
    44821 taaaacctag caacagcaag agttgcaaca acattcgcaa gttcatttac ataccactta
    44881 gttaatataa aaccccaaaa taaactgggt attttcaata cttacacatg tgcaactctc
    44941 ttaaatttga agtgaaccat gagtagtgca aatgataaag cttatcacat gccctcaaca
    45001 ccttatattt caagcgttaa gccctacttt gtaacaaata tcgctcactg caaaactatt
    45061 tacattttta ttatatcata aatatattat ttttgaatat ctgtaccaat ttgtggtata
    45121 ataaaaacaa gaagaactac aatctattta gacgtagagt gaagttcaaa tactaatgtt
    45181 tattcttttt gaacttgatt tttagttcaa aactaaagtc actcctgcca gagtggcttt
    45241 ttactttttt aaataattta ctatttaagt aaactattaa actggcaact aaacttgcta
    45301 gtacaccttg taaaaaatta tccatacata ctcacctccc ttctatacat tgggagaata
    45361 atcttttgta tgaactccac tctataaatt gtagattaca tcttcttgct aaaaatgtta
    45421 tagcatataa ttcttacata ttttacctat atattacttt tctaaagatt cgtctatata
    45481 tttctgtata catctactct atcctcgatt tgttacaacc ccaatcaaaa aagtagttca
    45541 acttctaagt tttatacaaa gcaggaaact caattattat tagaaaaatc aaaaaatact
    45601 cctataggta taccaatttt tttgatgcta actcttggat tacgttttgg tgaagctgta
    45661 tcacttatat ggtcagatgt agaccttgat aaaaaatctc acatgtaaat caaacattag
    45721 tttatgtata caataaaata atcttcaaag gccctaaaat ccctagattc aaaagaagat
    45781 tatttgttcc tgatgaactt ataattttgc ttaaagggga aaaattaaaa caaaataagt
    45841 taaaattaca gggtatattg aaaaatgaat ttgatttgat atgcttaaat aaaagattca
    45901 acccgtgagt tcaatcaact tttgttgttc attttaaaaa actattaaga gataataatc
    45961 ctagagatat aaaagtacat gaattaatac atgcaaatgc aactttgata ttactttcag
    46021 gtactaacat aaaagctatt tataaaatat tagtacatgc agatataaaa atagctatga
    46081 atagatattc gatattctca cttattagat taaatggata aagaaacatc tgaaaatata
    46141 agcaaaatac tattcaaata atgttcagtt ttatgtcaat taaatgtcac tcaaagtgct
    46201 ttttttcatt tgtcagttaa atgtcactta aagtaccttt ttcctatttg tcagttaaat
    46261 gtcagtaata tataaataag atatatttat aagaccctta aaatcactat tatttaataa
    46321 aatttataat tatatactat ttgctgttga cattggtatt ataccatagt ttatcattta
    46381 tattagaaat aaaattatta attaatagtt tcgtaatttt ataatagatt tacagggagt
    46441 gataataaat ggatacaaaa atatctataa acgaaaacat gagtctaggt aaaagatttt
    46501 ttaaatacct agcaccatct gtagttgcaa tgtgggtttt ctcactatat acaatggttg
    46561 atggaatatt tgtaagtaaa ggagttggag aattagcttt agctgctgtc aatatatcaa
    46621 tgccttttat taattttata tttgcagttt ctctattatt ttcaactggt gcatctacca
    46681 taattgcaat ctatctgggg aaaaaagata ttaaatctgc taacgaagtc ttttcattta
    46741 acttagtatc aataattata ttatcaataa ttatattagc tataactttt tttaatttag
    46801 atagattagc actattttta ggagctacag aatctacaat tggtatggtt aaagattatt
    46861 taggaataat aatatttttt aacggattct ttatagtgtc ttattcttta gaagttataa
    46921 taaaaactga tggctttcca atattagcta ctgttggtgt aataatatct gctcttacaa
    46981 acatcatact tgattacttg tttgtaattg aatttggatg gggtgtaaaa ggtgctggta
    47041 ttgcaactgg tttgtctcaa gtcttttcta ctattttctt cttgatacat tttttaagaa
    47101 aaaactctac tttgaatttt tcaaaattta gaattgattt taagacactt agaaaaattg
    47161 tatttatagg ttttcctgat tcaactactg aattaagttg tggtatagtt gttttacttt
    47221 ttaacttaag tcttactaaa tatattggag aaaatgctct tatttattat agtgtcataa
    47281 attatataaa tacattagta cttatgacta tgatgggtat aactcaaggt atgcaaccac
    47341 ttactagctt ttattatggt gcaggaaata tagataatgt aaaaaaatta ttaaaaatgg
    47401 ggataaaagc cacaataata gcatcagttg ctgtatttgc aatttgtatg gctttttcag
    47461 gaccaatagt ctctttattt atacatccag aagaaacaat gctattcaat gaaggagttc
    47521 gtgtatttaa aatattctct atatctttct tattggtagg aattaatgta ataatttctg
    47581 gattctttgt atcagtagaa aaaccatcaa tttctactgt tatatctctt ggtagagggc
    47641 ttgtaatagt tgttttaagt ctaatttcaa tgatactaat atttggtgga caaggaatat
    47701 ggatgactac tattgtttct gagtttatat gtcttatttt atcattagtt tttctaaaaa
    47761 agaatttttc tacattagac tctaatctaa ataaggttgc ttagatgata agagtgacaa
    47821 tatatgaaaa tatctaaata aaaaatacct attatacaat cttgcaaata ttagaccttt
    47881 gcaaaaatta ggattatata ataggtattt tatttatgta attattttat ttctaaatat
    47941 ccatagccat cttttattaa agttcctttt acttcatatt ctacaggttt tttaaatatt
    48001 ggaccatcta cgacaaatgt atgatactct ccatgttctc cacatgggtc tgcaccagca
    48061 ttttttatct tctccacaag ttctctagtt aatttttttc ctaaaaattc ctctcctaag
    48121 tgctttaagt ttacttttgt tacaacacta caaaatccac tgtctataaa ttcatatact
    48181 aaatcctctc tactctcttg ccataatggt aaatctactt tcataccaac tgcttcacat
    48241 ctatcagtat cccattttct atgactttct atatctatat ctccatatgc acatatcgtt
    48301 gctcccatgt ttttagcttt tattaaagcc ctctcaaagc tctcttcata tccttctaca
    48361 ccacactcag caactaataa aggtaatcct atattgctac ttacttgctt aagcatatta
    48421 tattctaaat tatgtgtcca tgactttcca tgttcttcac ttatagttgt caagagtgcc
    48481 acaggcttat atcctttttt caacattcga tttaatgcta atatactatc cttaccacca
    48541 ctaaatgaca ttacaaattt ttcatcagcc aattttaaca cctctttcat ctaactttgt
    48601 tttattaaca taattatacc aaatttttga gttgcatagc aaattatatt aaattgttaa
    48661 ttcactataa agaatgtccc taatattaaa agtataaccc ctatgtattt gtataaatgc
    48721 attgtttctt gtcccaaaat tacgctatca ataaaaaatc caactaaaac ttgggataca
    48781 agagttaata taagtgtatt tgatactcct aaatttggaa ttgcctttac tgtaaaatat
    48841 attattagac ctccaaatac tcctcctaat aacaacttat aattaaaacc atttatagat
    48901 actagacact ttaagtcacc tgtaactatt atacttgcca aaaaaaatat tgctcctaca
    48961 gttaagctta taaaggtggc cactaatgct gttgtacttt ttcctagctc tccatttata
    49021 aaagcttcaa gagctgtaga accacctgct aataatgcaa atattattgc ccataatttt
    49081 gtcatggaca aacctccttc tatataattc tattaataga agtttatgat acaacctatt
    49141 aattaattac taagtatagt ttaattttta tacactaggc tttatttgga tatgaatttc
    49201 tgttataatt gttctatcga ttttggaggt gattttatgt acacaaattt taatatcgat
    49261 tttaataact ttaataaaaa agaaaatgct attaaattta tgttaatggg agtattactc
    49321 attatattag gattattatg ccttacattt aagacattag gtataaaatt aatttcttgg
    49381 acttttggta ttgcactttt attctttgca tatttaaatt taaaaaatat taatgaacta
    49441 aaaagatatg ctactaaaga agaaattaaa ccctctatta atatccaatg ggttctaata
    49501 attgcatgta tattactttt tgtatttcct caaaaaatac aaagcatatt ttcattattt
    49561 ttaggatttt atttaatctt taatcaacta gtagcacttg taaatagtaa gaataatcct
    49621 tattctaaat ttacaacttg gaatatagtt aagattctat ttggtatatg ccttatatta
    49681 tctccacttt ttttatctag atttatagta tcgataatgt cttttttcat aatattattt
    49741 ggactagttc tatttttctc tggaaataca gcgagaaaat attaattatt ttctcgctgt
    49801 atttttatat tacttaaaat agaatttgtt taagttatct atttgtggta atatgttttt
    49861 tgtacaagct cagcgtacaa ttttattaga aataggtgat ttttttggat aaatttaaat
    49921 atgcttttga taataaaaga tatcatactt ggaattacta tcttagaaat acttttggag
    49981 aaaaagtttt taaggtatct ataaatgcag gatttacttg cccaaacatt gatggaagtc
    50041 ttggttatgg cggatgtact tattgtagca aagaaggctc aggtgatttt gctggaaacc
    50101 ctaaagataa tcttatcagt caattttata atataaaaga aatgatgtta aaaaaatggc
    50161 ctcatgcaaa gtatattgga tactttcaag cctatacaaa tacgtatgct cctcttgaag
    50221 ttttaaaaga aaaatatgag actatattag aacttgaaga tgtcataggt ctttcaatat
    50281 ccacaagacc tgactgtttg ccagatgatg ttgtagaata cttgtctgaa ctaaataaaa
    50341 gaaccaattt atgggttgaa cttgggcttc aaacaattca tgattctaca tctaaaatta
    50401 taaatagagg tcatgattat aaaacatttg ttgaaggtgt tgaaaaatta aagtctaaaa
    50461 atataaaggt tgtcgtacac attataaatg gtcttcctgg tgaagattat aatatgatga
    50521 tggaaacagc aaaggcagtt ggtaaaatgg gtgtagacgg tataaaaatc catctattgc
    50581 atgttataaa agatactcct atggaaaaga tgttacaaaa tggtatgtta actcttatgg
    50641 aacaagatga atatatcaat cttgtctgtg accaattaga aatacttcct gaaactatga
    50701 taatccatag actcactggt gatggtaaga gggatgaact agtaggtcct atatggagcc
    50761 taaaaaaatg ggaaatttta aatcaaattg atgatacttt aaaggctaga aattcttatc
    50821 agggctgtaa gtttgtttaa tacaaaataa taactataga aatggttata taaatatagt
    50881 cctttctata gttatttagt atttacaaaa caaaatatta atttgtatat ttatacaata
    50941 tataataaaa aatagatagt ctaaactgta tctacttata ttttatttgt actgtccact
    51001 ttattctata aaatttataa atagttattt tttaatacca aatataattt ggtataattt
    51061 ttgttggact ctaaaatgta taccaataaa tcctttttaa gtatataatt ctaaatactt
    51121 tcagtttttt caatctgctt taacttgttg gacttataaa atattcttat ttcatcataa
    51181 gaaagattaa gtgctactac tgcagatatt aacatcaaca tcactccaaa taacttccct
    51241 aaggaaaaac tttctcctaa tatagtgcaa ccaattatta ctgaaccaac taattctact
    51301 gatgccacaa cacctgcaac tgacaactct acacctttag atatacctgc tgcataaaaa
    51361 atatatgcaa gtgcagctgg aacaatgcct aacattagca tacaagataa aacatctaaa
    51421 tccttagcat aatttaagat ttcccaaggt cttgaagaag gaatcataaa tatagctcca
    51481 aataagaaac tgtatactaa tattgttgaa cttgaaaatt cctttaaagc atttttacta
    51541 atagttggca taagtgcata tgctattgct gataataccc caagtaaaag tccaaaagcg
    51601 tttaaacctt gaaaatccaa acgtccacca gtcactgcca taattgcacc aataaaacaa
    51661 agaataagtg aaaataattt gcttctagta atattttctt tataacatat ttttgaaaat
    51721 attgctaaaa acagtggtga tgtatatagt aaaactgctg caattgatac acccgcaatg
    51781 tcaattgctt taaaataaca taaattaaac attgcctgac atataatacc tattattact
    51841 gaatacataa ttcctttttt gcttatcttt aagatttgtg gtgtccttat agatgaatat
    51901 acgcctaaaa ctataaatcc aaaaaacaat cttgtaaatg ctacttgttc tgatgtcagt
    51961 ccatttccca ttaaaaactt tccaaataat ccaagtgtag cccataataa ccctgctatt
    52021 gctataaata catacccttt acttttttct cccattttaa attcccttct atttttattt
    52081 agtcaattta cactcttctt tttaagcaaa aactatgcca tcttaaatca atatatatcg
    52141 actctaaaac cctagtcttt ccaataatac taataaattt tcaatttttt tatatttatt
    52201 tttcgcttac tttaagttga tttagactta ttttaattgt aaaatgagtt atatataact
    52261 tatttaaagt taaaatagac tgaaacttat atataaatat caaattttaa gtatattaat
    52321 caattaaacc tattttaata tatcattaaa aatttaggag gaaaatataa aaatgaattt
    52381 agatttggaa ttttatcaaa aaatattaga agcttcccat gatgaaatat gtgtttctga
    52441 tgataaagga ataataatat attgtaataa agcatttgaa gaaaattatg gtctaaaaaa
    52501 agaagatatt ttaggaaaaa atgtttcttt tttagaagac tctggatatt caacaaaaag
    52561 ccccatacca attgtattaa aaacaaagac taaattttca ctggaacaag atactcaaac
    52621 agggaaaaag cttattataa ctgctacccc tatatttgat gaaaatggaa acttagaatt
    52681 tactgttgaa aattgtagag atataactga acttaataat ataaaaaata aacttgaaga
    52741 cacaaaaaaa caagtaaaaa aatataaatc tgaagtagaa acactataca gaactgcact
    52801 tagaattgag gatactgtaa ttatggacgg aatagttatg agaccaatca taaacacagt
    52861 aaatcatgtt tctaaaacgg atgtaagtgt acttttattg ggtgaatctg gaacaggaaa
    52921 aagctcactt gctagatata tacaccacaa cagcaataga tctaatggcc catttataac
    52981 aataaattgt gcaactatat ctccacaact tcttgaatct gaactttttg gatatacttc
    53041 aggtgctttt acaggtgcaa gtactaaagg taaagttggg ctcgtagaat tagctaatgg
    53101 aggaactctt tttttagatg aaataggaga tataccacaa aatctacagg caaaattttt
    53161 gcaattaata caggatagaa cttttactcc agttgggagc ttaaaaaata aaaaggtcga
    53221 tataagaatt atatctgcta caaatgttga tttagtttca aaagtaaaag aaaaaaagtt
    53281 tagagaagat ttatactata gattaaatgt tatagaaata aaattgcctc ctcttagaga
    53341 aagaagggat aatctagtgg aaattataaa atattatttt aataggtact caagtgactt
    53401 caacctaaat aaaactattt ctaaagaagc tatggatgct attgcaaatt atagattccc
    53461 aggcaatata agagaattac aaaatataat tcaaaaaatc ttgcttactt gtacagataa
    53521 tcatataaca atagatgact taccaaacat tcttacaaaa aatatacata ttaccaataa
    53581 tggaaataaa acacatatat cacaaattaa taaggttatt atatctgact caaaatctac
    53641 taattataaa aataaaaatt ttgacacttt aattaaagag tatgaaaaaa atataatttt
    53701 ggatgcttat gaaaaatttg gtagttctta taaagtagcc aaacaccttg aaatctcaca
    53761 gtctaaagcc aataggttaa ttagaaagta tactaatact taattttaaa tttgataaat
    53821 aaaaacttaa cactatttac atattgtaaa tttggccatt tactgttatt atgaatatgg
    53881 ttgaaattat ttaaataaat actgttgact tagtttcata tatttaccat taaactttta
    53941 tcataaatat catatcataa taatatattt aataagtcta ataaactata cgaggtgtaa
    54001 atatgttaat gaatacccat tttattatgg caaaatcaat acttgataat atagatgaaa
    54061 ataaaacatt ctttataagc gaaaaaaatt ttatatatgg caatataaag cctgatgctt
    54121 tttctaaata taaattaaaa aaacattatt tagatgagtc atttaatatg attgtttcta
    54181 aaataaacta tctatgcagt cttaatatag atagtctttc taaatacttt tcagtaagta
    54241 gacttagtca ggaactagga gtcatatgtc attttttatg tgattttttc tgtgtagctc
    54301 acagtgaacg ttgggagttt aagcatagct taaataaaca tgttacttat gaaagagaac
    54361 ttggagcatt tgcaaaagat gttgatttat ctaaaattaa atgtggtact ataaatagta
    54421 gttttgagaa gttttttact aaactttata gtgattacaa aaagaaaact gattatatga
    54481 atgatttaaa attttcagct tatacttgta atagtgtcat aaattatata cttgactcta
    54541 ttttatctaa tacaataaaa tcatatcata tagcaaattg cggttaactt aagaattttt
    54601 aaacttatat aaacttataa ttgaatataa ttaaaatgac tgctctatag aatataattt
    54661 tatacttctc taggacagtc attttttata ctaactattt atctccatta taacatctat
    54721 ggcacttttt acactatcta ctacataatt tgcactttgc tttacatctt cccttgcctt
    54781 agacattgca aaactatatt taaatccttc taacatgcaa atatcatttg gagaatcccc
    54841 aatagtagca acttcatctg gacttacatt taacgttttt attacatgct ctatacttcc
    54901 tctttttgac acacttttag gaactatatt taaagtatat gttccagaaa aatatatttc
    54961 taagacttca ctaaactcac tttttagata aagttctatt ctggataact cttccaaatt
    55021 ttcagaacat acgcctatat ttcctataag attatcaaaa ctacttcttt tttcaaaatc
    55081 tgggtcaact ataaagtcac tagaataatg tctaaaagca gtggtatcac tacccacaat
    55141 tacatcaccc ttatatttaa aataaagttg tgcatcactt gactcaaatc tatcaatgac
    55201 tttttttact aaattatcat ctatcgttct tttaaaaatt acattataat ctttatcata
    55261 tataaatgaa ccattttcac atacataata tccattcata tctaaactat ctttgataat
    55321 attatgtgct tgtttaaaaa ttctacctgt agcaacatta aactgtactc cctttttttc
    55381 tatttcttca attgctacta tatcttcttt tgttatggtt ccattttcat atagagttcc
    55441 atctaaatca caaaatatat gttttatcat aaattaaaag cctccaaaaa caattttata
    55501 ttttactaat actttaatca aaataactta aagcttttct aattgtattc tcaattcatt
    55561 aagcaaatct ctagtagctc ttaatcttat ctttcttcta tccccattaa atatattttt
    55621 ctttactatt gtttttccat ttatatatat tgcagtataa accagtccca caggcttctc
    55681 tttggttcct ccaccaggtc cagctactcc agttgtagat atacctatat tagctttaag
    55741 tcctttagca acgccctcag ccatttctat agctgtttgc tcacttactg ctccaaactc
    55801 ttccaaagtt tctcttttta ctcctaatct tttcatttta gaatcattag aatatgttac
    55861 acaaccttca agaaatacag aggatatacc tggatagttt ataagagatg aagaaaccaa
    55921 acctccagta caagattcag ccactgctat tgttagattt ttttctacaa gtagcttaga
    55981 aacagcatct tctaaagcag tctccccttc agatatggaa atatctcctt cagtatatac
    56041 atatttacca actctacttt ttattttttc ttctactggt tttattaatt taaaagcttc
    56101 tctttcattt tcagcctttg cagttattct tattgtaact tctaattctt ttgcatataa
    56161 agcaactgtt ggattagtct gctcattaat tatatcgaga atttctaatt ctagatttga
    56221 ctcacctatt ccatataatc ttaaagtctt agatactagc atttcatttg tgaattgttg
    56281 taagtaaggt ttgacactct cattaaacat agctttcatt tctcttggag gtccaggcaa
    56341 tactattata aatttaccat ctttttttaa aattgcccct ggagctgtac cattattatt
    56401 ttttagtact atagcatctt ttggaaagta cacttgtttc atattatttt cggccatttt
    56461 tttccctgtt ttaacaaaga aagattccaa aacctctagt gaaggtttat gtagttctaa
    56521 tttctgacca aagtattctg cagcagtttc ttttgtcata tcatcaccag ttggcccaag
    56581 accacctgta gtaattacaa aatcacttct ctttaagctt tcatcaaaac attctaaaag
    56641 tctttgtttg ttatctccaa cagtactctg atggtatact tctattccca atgatgcaag
    56701 ttctttagct aaaaattgag aatttgtatt tactatatct cccaataata tttctgttcc
    56761 tacacttatt atttcagctt tcaaaattta tcactccttg atttatagcc attaagacta
    56821 gtcttaagtt cataacaata attttagcaa aaataataac ataaataaag ttaaaaaatc
    56881 atttaaacat atctttaaac tagattatta ttctaaaacc acacataata taaacttcgt
    56941 atatagtggt actttcatcc tcaactgtta attcatataa ttaagtatgt aaataaaaag
    57001 tttactttaa aataataaaa attaaaatag gagtgtataa tatgaaaata gcagttataa
    57061 tgggtggaat atcatcagag agagaagttt ctttaaattc aggaaaagag atatataata
    57121 accttgataa aaataaatat gaagttgtaa aagtaataat agatgataaa aaagatatat
    57181 ttacaaagat accagaagat atagattttg caatacttgc tttacatgga aaatttggtg
    57241 aagatggatg tatacaatca atacttgaga ctatggatat accatactct ggatgtggac
    57301 ctctttgcag tgggatgtgt atggataaaa atataactaa aaaaatgctt agagattcaa
    57361 acctacctac tgctccatgg gttttagtaa aatcagttga tgaaatagac tatgatgaaa
    57421 tagataatat aggttatcca gtatttataa aaccaaactc aggaggttca agtgtagcca
    57481 cattctttat tcattctaag gatgaagttg aagaagcagt tagaaaaggt ctggaagttg
    57541 atgaatttgt aatgattgaa aaatatatac caggtggaga atatacttca ttcatattaa
    57601 atggagaagt gttccctaca atatctataa aatctgattc aggattcttt gattatgaag
    57661 ctaaatactc agttgaaaaa ggtgcaaagg aagaagttgt ttatttagat gaagaacttc
    57721 aaaaaagagt aaacgaaatt tctgagactt gttggaaaat ttttaattgc aaagcatatg
    57781 taagagttga tatgattata agtgaaggta ttccatatgt tcttgaacta aatactcttc
    57841 ctggaatgac tcaaactagt ttaattccta gaagtgctgc tgctagaggt attaagtaca
    57901 gtgaactatt agataaactt atagaatact ctttaaatta gatgaaataa tttgaggtgg
    57961 taatttgata ttttcaaatc taaaattaaa tgataatgaa ccaatttata tacaacttaa
    58021 aaattatata agtgatatga tatcaaaagg actaattcca gacaatagta agctcccttc
    58081 tacaagggag cttagtcagc ttttacaagt tagccgaaat tctgtagttt taacttatga
    58141 agaattaaaa tcagaaggat taatctactc tatttcagga aaaggtacat ttgttaaatc
    58201 aaagaataag tcttcaaata ctacatggtc attaaactgg gattgtttag agaatacata
    58261 ctctaaaaaa gccaatgaat tggacattat aaaaagtgaa attccttgga gctctgacct
    58321 gatttccttt aaaagtattt ctccagatgg agatttattc gacatggaag aattaaaaaa
    58381 atccttttta aatagaattt cactagaagg acataaatta ctcaactatg gatatgcaca
    58441 aggttataag ccacttattg actatttact agaatatatg acaaacaagg gtgctgatat
    58501 aagtaataaa gatatactaa taacaaatgg attcacagaa ggctttgata ttattatgtc
    58561 atcttttacc caagaaaaag actacataat atgtgaaaat cctactcata atactgctat
    58621 aaaaattatg aaatctcata acctcaatat cttaggtgta gatataaatg aagatggttt
    58681 ggacttcaat atgctagaag acaatttagt taagtataaa aataaaataa agtttgcata
    58741 cattacaccc tcttatcaca atcctacagg aattgtaatg actcctgaaa ataggtacaa
    58801 attctataat cttatgaaaa aatacaatat agcaattata gaagatggat ttaatgaaga
    58861 attactctac aatagttctc atatatttcc tatctgttcc ctagataata tgaataatgg
    58921 ggtcgtatat attggtagtt tttcaaagat tttatttcct ggaatgagaa ttggatggat
    58981 atttgcagat aaaaaagtaa tcaataaact agaaagtgta aaaaggtgca gaaacataca
    59041 tgtatccttt ttagaccaag gaattttatt tgattattta agtaatggag gttttgaaaa
    59101 atacattaaa aaaatacgta aattctatgg agacaaattt aactttgcat ataagtgtat
    59161 aaaaaaatat ataaaaacag aatatatctt gggtgatggt ggtttgcata tatttataaa
    59221 actaaaaaat atagatacta gagttttatt agaaaaatgt tatgaaaaaa atgttatatt
    59281 tatgcctgga gatttatttt ttacagataa ctctggtttt gatactttaa gactcggatt
    59341 ttctaggttg tcttttgaag acattgaaat tggaataaaa ataattggag aaactataaa
    59401 tgaaatgttc taggttaact aaatattgtt agcctagttt atttttatga ggtataatat
    59461 atatagttta tatgaatcta atactggggg ataatatgag taaaaagtca aaacgaagaa
    59521 aaattaataa attaaaatta acgattgtaa taactgtatt atttcttgct ttattatcta
    59581 tatatgagat actgttctct aatcccaaca aaaaaggtaa tataaagagt caagaaacta
    59641 tgcaaaataa aaataataca acagatgatt ctaaaaataa tcaaagctct accaaaaagc
    59701 aggaagataa taatatcaag cctacttttt catattcttc aataccagat aatataaaaa
    59761 ataaaatgat tggtaaatct atgcctactg atgaacctat aagctttgat agtctatctt
    59821 atttaaaact tacatattat ggatttgatg aaaaaactca tcaaggagaa atgatagtaa
    59881 acagtgaact agctccagaa gtagtggata tttttaagga attatacgaa aaaaaatatc
    59941 caattgaaaa aattaagtta atagatgact atgatgctgt agatgaaaaa tctatgtctg
    60001 ataataatac ctcatcattt tgttatagaa ctatagctgg tacaaatgta gtttcaaatc
    60061 atggtaaagg acgtgctata gatataaacc cattacagaa tcctcaagtt tctggaaatg
    60121 atgttacacc taaagtaagt acagtttatg ctgataggtc tagcacaaaa tttggaatga
    60181 taaaaaaagg tgatgattgt tataatgctt ttgtaagcag aggttggagt tggggtggct
    60241 attggaaaaa cccagattat caacattttg aaaaataata gattagaaat aaaggtgaat
    60301 tatatgaatt taatgacatt ggaaaatata agtaaaagct attctgaaaa aaaattacta
    60361 gaaaatatat ctcttggaat aaatgaaggg gaaaaaatag gacttattgg tgtaaatggt
    60421 actggtaaat ctaccttact caaaattatt gcaggagttg aagaaagtga gactggtaat
    60481 ataacaaaaa ctaatggtat taggatagaa tatctacctc aaaatccaac ttacaatgaa
    60541 aattcaactg tacttgaaca agtatttaat ggaacttctg aagaattaaa gctacttggt
    60601 gaatatcaag aaatcctaga aaaacttaat tcaaacttta cagaggaatt aaataaaaaa
    60661 ttattatcag tacacgaaaa aatagatgcc ttaaatcttt gggatttaga aagtgaagct
    60721 aagtcagtac ttacaaagct tggtataaat gactttaatc aaaaaatagc agaactttct
    60781 ggtgggcaaa gaaagagagt ctctctggca tcagccctta ttacaccttg tgagtttttg
    60841 atactagatg agcctacaaa ccatctagac aatgatacta tagattggct tgaggaatat
    60901 cttaattcca gaaaaggctc attgcttatg ataactcatg atagatactt tttagaccgt
    60961 gttacaaata gaattattga actggacaaa ggtagattat tcagttatga tgggaattat
    61021 tcaatatttt tggaaaagaa aatggaaaga ctttcgctag aagcaagtat tgaagataaa
    61081 agacaaaatt taataagaac agagcttgcg tgggtaagac gaggagctca ggctcgtagc
    61141 actaaacaaa aagctcgttt acaaagattt gatgaactta taaatagaga ttcttttaaa
    61201 cctgatgaaa atctcgatat atctgttgca tcaagtagac ttggaaataa aataatagaa
    61261 atacacaata tatctaaatc atttgaagaa aatactgtta tagataattt agaatacact
    61321 ttaactcgta cagatagaat tggtataata ggcaaaaatg gtatgggtaa atctaccctt
    61381 ataaatatac ttaatggaga aatagagcct gacagtggat atatttcaat tggagaaacg
    61441 gttaaaatag gttgtttttc tcaagacgac tctcatatga atattgatat gagggctata
    61501 gactatgtaa aagaagctag tgactatata gaaacttcag atggtactag gattacagct
    61561 tctcaaatgt gtgaaagatt cctttttaat ggtactatgc aatatacttt gataggtaaa
    61621 ttatctggtg gtgaaagaag aagactacat cttcttaaaa tccttatgac agctcctaat
    61681 gtgcttcttt tagatgaacc tacaaatgat ttagatattg aaacgcttaa aatattagaa
    61741 gaatacctag acgaatttaa aggtgtagta gttacagtat cacatgatag atatttctta
    61801 gatagaattt gtaataaaat atttgcatat gaaggtaatg gaaaaattca tatctataca
    61861 ggtaattaca gtgattatct tatttataga gagattcaag gaattgaatt tgaagaatct
    61921 aaaaaggaat cagttaaaaa agatgactct actaccctaa aaaaagaaaa acctaaaaat
    61981 gataaaaagc ttaagttctc atataatgaa caaagagagt ttgaaaatat tgactctgat
    62041 atagaaaaac tcgaatctaa aattgcaaca cttgatgaaa gtactgcaaa attttcaact
    62101 gattttacta aacttcaaga aattttagat gagaaatcta aactagaaaa agaacttgaa
    62161 tacaaatatg aaagatggga atatttaaat aatctagctg atgaaatagc taataataag
    62221 tgatattaaa ataatcttaa gtttaataag ttttacttta aatctgtact ttataaacat
    62281 tttaaaggaa gtgtctcaaa atgaactttt tagttttatg agacactctt ttttatgaga
    62341 aatcaaatat gttttcatca tttcaacaat acaaaagagg cttatctcta ttttgagaca
    62401 gcctctttca taattacctt ctaatttata tgctctaata tatctataat aattcttatt
    62461 atatctatat atccagtctt tcaatatagt gacaattaac ttcaatatga tttaaaaata
    62521 ctaacaacct ttcataaagt ggatgagatt cttctccata tttagcttct aggttcttgc
    62581 ctatttctct aacagtcctt tgaccatcaa tttgtaaaaa aacaaaactg gaatattcat
    62641 ctagttctat ttttttgtat ttaggtattc tagcttttaa ctttctaaaa aacttttgaa
    62701 ttttatggtc ctgtttttca agtatagtaa caacactatt ttcagctact tcatattcaa
    62761 gtccaacagt aattttaaat acaatatcta aaacatcatt actcttgctc attatttttt
    62821 actttagata aaacaatagg taatgctgta agcacaacta aaactaccaa taaagcaatt
    62881 gccattgaat ttgttgcagc aaatccactt ggtacctttg gagttacaac tccagttact
    62941 tgtaatatta tacctattaa accaatgata gaaccaccag caacaagacc agaagataaa
    63001 cttataccat tagaaacttt aacttctttt tctttttcag ttttagatac taattcaaca
    63061 aataaacgaa ttaatgctcc aactaatatt atagaagttg ttgcaattgg taaatagaat
    63121 cctatagcta tagtcattat tggtaaattt aatgcatata gaacgattgc cataaatact
    63181 ccaacaataa tcataaccca aggtaaacta cctgacataa taccagaagt taatgttgac
    63241 attaagtttg cttgtggtaa tgcaaattgt acattatcac cagttgctct aagttggtca
    63301 gaaagtaata aaattactcc tacaacaact ataacaccaa ctatacttgc aattgtaaag
    63361 taacgttgca tttcgttttt gctaccacca ataatataag ttactttttg agattgagta
    63421 taacctccag ctatagcaat agcaacaact ataaatgaac caaataaaag taatgattta
    63481 ttagcttcta aatcagtcca tcccattata acaaacacta atgttacaat aactagagaa
    63541 gctatagtca taccagaaac tggaagattt gatgttccga ttgttcctgt taaacgacca
    63601 gctactatga caaataataa agataataaa agagatatga tagctccaat aattgccata
    63661 acaatgttac cagaaattaa gaatgctgct aaaaatccaa taactactcc acctaataaa
    63721 agtatcattt gtatagatga accttcttct ccttctccag cacttgattt agctttaagt
    63781 gtttctttta tagaagcgat tatagttggt ataagtttta ttgcaccaat aatacctcca
    63841 caaagcatca taccagcacc tatatatttt acataactac tagatattgc tccaacatcc
    63901 atttggttaa gaggcattgc aggattattc cataccatag ctccatcttt agccatatct
    63961 gtaaagtatc ctattaaagg tgctatacca aagtttgata aaatacttcc tgcaaacatt
    64021 gttaaagaaa cttcaagccc tactataaat ccaattccta aaagtagagg atttacttca
    64081 atatcaaatt tccatttgta gaatttgctt cctacaagac tcattacatt gtttgctaca
    64141 tttaagaatg aaccagttaa tacagtaata aatccactta ttacaaatcc aattcccatg
    64201 tacttaattg aatctccacc agcctctgaa gcaacaagtg tttcagatat agccattgat
    64261 tctgggtaca taagtttacc atgttcttca actattagat agttgtgaac tatagcagca
    64321 attcctatac caaataaaac tccaccaact ccaacagcta agccttcaaa gaatgtaatt
    64381 tggcttccaa ttaatataac tgctggtaat acgaaaataa atccacttgc aacagattct
    64441 ccaccacttg acataccttg gattaagttt ttaccaagaa taccctttga acgagcaaat
    64501 gctccaacaa aagcagaacc tattatagct cctggaatac ctgcggcaac tgtaagaccg
    64561 gctttcattc cagagtaagt tgtagatgcg gcaaaaatgg cagctaaaat aataccgata
    64621 atcagtacag ctacatttcc accggttctg gacttatctg tgatatatgg aacgtaatct
    64681 tttccactaa cctcaccata agcaccctta ggcaattttt tgttcataaa attttcaccc
    64741 cttttcaatt tgtatatatt ataacatata tacatataaa acttaacttt ttattatttt
    64801 acaaatagcg agtcaaaact actaaaattt aaccctatat tattaatttc tacttttaga
    64861 tatttttatg ctaattttct ttttattttt caattctact aaaaactatt aagatataaa
    64921 ataaaaaatt tttttaatgt aaaattaatt ttgtaaaaaa aatgctttaa aacacggaaa
    64981 agtataaaaa atacaataat cattcttata aataaatttt caccatagta aatatataca
    65041 gaaaattctt gtttttatgc aaattgattc ttttataaaa ataagtgtca taaagaaatg
    65101 tctgaaatca ctttatgaca cctatcataa taaaaaatta ttctggtaat gctcttttat
    65161 ttacttttcc gattggtgta actggtatct tatctatcct cattattatt gttggaatca
    65221 tatatggagg tagatgctca tttaaatatt ctctaatagt tctttcattt atcttaccac
    65281 tatcttcctc atcaattaca taatatgcac atatatacat atctccatca tcatttgttc
    65341 tcgatataca aacaacactt ttaatttctg taatattatt tattatattt tcaatctcat
    65401 atagctctat cctaaactca tcaattttta cttgattgtc catccttcca atataatcta
    65461 aatttccatc atctaaccat cttactaaat caccagttct atacattaac ttattatgtt
    65521 cacaagtttt gtaaggattc tctacaaata cttgctctgt tagacctttt ttatttaaat
    65581 atcctcttga tatttgaatg cctgatagac atagctctcc tggtgctcca attggacata
    65641 gtttgttctt tttatctaat acatatgcat aagtattaaa tataggtttt cctattggta
    65701 tttttccata ttctctgtcc acatgaaaag aagtcgatac aacagtaaat tcggttggtc
    65761 catactcatt atatagttca taattacgct ttctatatcc ttttaatctt tctcctccag
    65821 tctgtacaac tctaagcgaa ttattattgc aattttgtat aaataacctt gcaaatgctg
    65881 ttggcaatgc tagtatagtt atgtcatttt cctcacagta ttcatttact gtatattcat
    65941 caaatttagc ttcttcaggc ataatatcta ttgatgcacc tacaagcaaa taagggaata
    66001 gttgtttcat tacagcatca aaactgaaac ttaagtatat accacatata tcattttctg
    66061 tagcgcttat agattttacg ctataataac acatatttac taaactctta tgttctatag
    66121 ctatggtctt tggcctacca gttgaccctg aagtagatat cgtatatgca caatttgatg
    66181 atgttatttt ttcagttaat tcatatccaa gcttaaacat ttcttcatca tttatatcga
    66241 gtactatggt attctcattt acaaccttac ttttgagttc atctgtagtt atcactactt
    66301 ttgcattact atcttcaaga aggtaattca atctttcttc tggattactt gtgtctattg
    66361 gaaaaaatgc tccccctgat ttcataatcc ctattgctgt aataattatg ttaatatctc
    66421 ttggtaacat tacagctact atgtcttcac tttccactcc tatatgattt aaataacctg
    66481 caagtttatc agttacttca tccaattctt tatatgttaa ctttctattt tcatccctag
    66541 cagctatatt actaggtgtt accttaactt gctccctaaa taaatcaaca taacttttat
    66601 catagggtat ttcatattga ttattattaa agtcttccaa taatactttt tcttcttcct
    66661 tacatacaaa ttctaaatct tctattaaaa tatcattatc ttctattatt tgctctatta
    66721 tataatcaaa ttgatttaaa attcttctaa tagtttctct tttatatata gatggtttat
    66781 actttatttt tattttaagt gccctcttag tatatactat tacagataaa tcatatcctt
    66841 ttttttctat gtcataatca tatgataaat caaaactttt agctataaat attgtgttta
    66901 taagcttagt atttagatga tttttattct ctatatctga taacaaatag tatccatact
    66961 ctaaagacct gctccactgc ctttttagct tccttacaac atctataaat ttttcacttt
    67021 gtctaactct tactcttatt ggaattatat tcattgtttt accaaaaact acatcatctt
    67081 catatatata cttttgaagt ataaggccat atatagtttc tatgatagag tctatgctaa
    67141 tattgttcac tttagaatat tgaattaacc tttcatgttt ctcaatattc atcttaaaaa
    67201 cctcatctac tacttcatca gaacaatctt tataaaaaaa atcatttgga atttttgcta
    67261 tattcgtata atcatctaac aaatccatcc aataattcat agctcgttct aaattaactt
    67321 catacatatc aaaattcccc cttactacta agtctataga aaaaattctt ttggaatttt
    67381 attttcacaa tatataaata tattaataat acatatgcaa gctctaaaaa catgagcttg
    67441 cataaaatta cacttattat gactactaaa ttcgtaatat ttacaatgtt taaaatatat
    67501 tataacacat atatgatttt atttttctac atttatataa tatataaatt acaaatagtt
    67561 atttaactaa tatataacaa taccttttgg aatatgatat attatattaa ttaaattttt
    67621 ataagataag ttatacttat aggagggaac catataaatg aatatttatg ctcatagggg
    67681 gtttagtgga aagtatccag aaaatactat tctagctttt aaaaaatgtt tggatatgaa
    67741 tatatatgga atagaacttg atgtccacag aactaaggat ggaaaaattg tagttattca
    67801 tgatgaaaag gttgatagaa cttttaatgg acatggtttt gtaaaagact ttactttaag
    67861 aaaattaaaa actctaaact catcttttga aggatatcaa agcaataaag aatgtaaaat
    67921 tccaacttta gaagaagtat taattctaat ttcacctaca gaccttattt taaatataga
    67981 actaaaaact gacaaaataa actatcccaa tatagaaaaa gacgttttag agcttatttt
    68041 aaagtataat atgaaaaata gagttcttat atctagtttc aacagcaata gcttaacaaa
    68101 ctttcataaa ttagacccta gtgtaaaaac aggattattg tgttatttac ctataaacaa
    68161 tgtagtcaat tttgctaaat ttctgggtaa tagttacctt catccacctc tagttttagt
    68221 aaatgaatct ctaattgaac tttgtcacaa aaatctactt ggtgtcaatg tatatactgt
    68281 aaatgaagag gatgatatac tacactgcct aaaactcaat gtagatggta tttttactaa
    68341 ctatccagat attgcttcaa atcttttaca ctcaaaacaa tacagctaat tatacaatag
    68401 tttgcactcc ttgactttta tataattaat atgtacaatt ttattaaatt tatcttggag
    68461 gtataactat ggataactta ttaaatgaac ttgaagcttt aaaaagtaat ttagataatc
    68521 taccaataga aaaaatagaa aattatgatt tgagtaaaac tgctttattt ataattgatg
    68581 ttaataatgg ctttgcaaga caaggtgcat tatactctcc tagagtagag tctttaataa
    68641 agccaattga aatgtttaca aaaaaaatat caaacaaatt aaataaagta atagcattta
    68701 ctgattctca tactcctaaa tcaatagaac ttttgagtta tcctgttcac tgtttggaaa
    68761 atgatgtaga aagtgaattg gttgatgaac ttaagtcgat agaaaaccta caaattcttc
    68821 ctaaaaattc tactaatgga ttttttgcat tagaaaattt ggattttgat aatatagata
    68881 atataattat agttggcgat tgcacagata tatgtatata tcaatttgca ataactctaa
    68941 aatcatattt taatcaacat aatattgaaa aaaatatagt tgtacctatg aatttagtag
    69001 atacttatga tattcctaac gttcaccctg ctgagatttt aaacttagta tttttcaaca
    69061 gtatgattca aaatggagtt aatgtattaa aagagattcg ttaagcctct aatactttac
    69121 atccatataa tacaattatc agatatttat ttttaataaa atttctaata gaaaaacaca
    69181 gttttagtga gaagattaca atttaaaaca ctatctatta tgactaatct tcacaatata
    69241 aaaaatcgca gtttagatat tccttataca aatttataag gaataataaa ttgcgatttt
    69301 tatttttaag tagtacaatt aattgatact acttcagtat ttaaattcat tttttaataa
    69361 tcatacttat tcgtagtttc gcacattact acctttattt ttttattaaa catattctta
    69421 tattctaata aaaactcatt tagttctgaa tccataagat ttatttttct atcactacaa
    69481 agcattatct tttcttggtc gattattaca ttaatatcat ttaagtcatt ttttataaat
    69541 gttgttatac aactctttgg ttggattttt tctccatatt tctcataaaa tcctgcactc
    69601 ttcttaaatg actctaaatc ttctgtagat actttgctgg aagtattatt actcataaaa
    69661 cctgctgtag aagggtcgat tccaaagttt ctaagttgtt tttctacttc ttcagtgtcc
    69721 ataccatatc tctccataaa ttgcttttgt attttcataa atttttcttg agatatgttg
    69781 ttatctctca tataatcgaa tatttttctt gaaaactcag ccatagacat ctttccatcc
    69841 ataacagaaa aatataagtt atatatgtat tgctcaaatt tatctacatc agaatcttta
    69901 actttgttct ttagttcgtt aaagtctatt attctatcat cagacatttt tcatcctcct
    69961 agctaaattt ttacttgtat aagattatac catatttcta ttatatttat atacacacta
    70021 tttttttaat ttaacgattt tttctgtagc atctaattcg cacattctgc ccaaaggaat
    70081 agttatcatt gggatacaat gtcctgactg aagattatat atagaaggtt tattgacctt
    70141 atttgcaaat tctattagta attccatcaa atcattttct tcaatacaat ccttaaaatc
    70201 tccaaaaatt ataccattac attcctcaag ttttcctgaa gaatatagtt gtgttaacat
    70261 tctatccagt ttatattgag gttctccaat ttcctcaata aacaaaattt tatcttttgc
    70321 atctatttca tattttgttc ccattgtggc aattattaag gataaatttc ctcccattat
    70381 tattccctct gctttacctt cacatacagt ataaatcttt tcttcttttg gattttctaa
    70441 atataattca tctttaaatt ctaaagcatt taccaatgat ttataggtaa atttatccca
    70501 tttacctaca tttgctgcca ttattccatg atatggtaaa agaccacaat ttttatagaa
    70561 agctaaattt aaacctgtta tatcagaaaa acctataaat ggttttggat tttgctttat
    70621 tatatcataa tttattttat ccaatattct tgttgttcca taacctcctc ttaagcacat
    70681 aattatatct acatctttat ctaaaaacat atcttctata tcccttgctc taatatcatc
    70741 attaccagct aaataacctt tataatttaa actacaactt tcagaaaact taacttcgta
    70801 accataactt tctaaattaa actttatttc ctccaaactt gtatttctta atggcccaga
    70861 tggcgcaatt attcctaaca tttaaacacc tcttcttata aaatgatata ttcttctcca
    70921 tactaaatat ctctaatata attataagat attttatttg tacttgatac ataataatga
    70981 tttacataaa ataatataat taatgaagaa aaataaattt ttaatatagt taggatgtgt
    71041 tttatgctta atataaaaac tctttgtcat gagataaatg attgggttat aaatataaga
    71101 agagatttac ataagactcc agaacttgga ttagaagaat ttcaaactaa gaaaaaaatt
    71161 attaaatact taaatgaaat aggtataaat tatattgaat ataagaatca tacagggata
    71221 actgcataca ttaacgtgag tccaaacttt gaaacagttg ctataagagc tgatatagat
    71281 gccttaccta taacagaaga acttaattat tcttataaat ctattaatat tggcaaaatg
    71341 catgcatgtg gtcatgatgc acacactgct attttactgg gtacttgtaa tatactattt
    71401 aaattaaagg attacttaaa tgtaaatgta aaattctttt ttcaacctgc cgaggaaact
    71461 attggtgggg ctcaacttat gatagaagat ggatgtcttg aaaacccaaa tgtaaaatat
    71521 atatttggac ttcatgtaaa tcccaatatc aacaaaaatc taattgaatt aaaatacaac
    71581 actctaaatg cttccaccga tacacttcaa ttaactgtac atggttcaaa atgtcatgga
    71641 gcttatccac atcaaggtat tgatgctatt gttatatctg ctcatattat tacagctcta
    71701 cagacaatcg ttagtcgaaa cacaaatcca actgattctg tggttatttc tctaggaaag
    71761 attgaaggtg gaatcaaaga aaatatagtt tgtgacaaag tggttataag gggtacttta
    71821 agaaccttga ctcctgaaac tagagagttt tcaaaaaaac gaattagaga aatttgcgat
    71881 tttacttgta aaacatttgg aggaagtatt tctgttgaaa ttgaggaagg ttatccagct
    71941 cttatcaatt caaaccatct agtagattac gtcaaacaaa atgctgtaga attgtttgga
    72001 gaagaaaata ttatccttaa agactcgccc actcttgggg ctgaagactt ttcgtatttt
    72061 ctaagacact gtgaaggagc tttttaccac cttggttgtg caaatcgtga aaaaaacatt
    72121 acttcccctt tgcatacctc tacttttgat attgacgaag attgccttat tactggtgtc
    72181 atactccatg taaaaaatgt attatcattc taactattaa tatttttatt tattatttta
    72241 tattgaccct cacatgatgt catgttatac cctaaaatta caaatgataa attaaatagt
    72301 tggaggtaat attatgaaag aaatattaat aaatcctata ggtaaaatat gtattcaagg
    72361 cgaagaggtc tttattaaat tagacaaaaa gtatgtacct gcattaaatg aactcgacga
    72421 tttcagtcat ttaaatgtat tttggtgggc tgatgggttt gataatcctg aactaagaag
    72481 tattttagaa accccaaaac cttataaaag tggaccagat gttataggaa tatttgcaac
    72541 aaggtcacct ataagaccca atccaatagc attgactgct gtacaaatta tcaatatcga
    72601 ccatgaaaat ggtataataa aaataccata tattgatgct aatgataata gtcctgttat
    72661 agacttaaag ccatatactc caagcgttga tagggttgaa aatccgtcca ttcctaaatg
    72721 gtgtagtcac tggcctaaga gtgtagaaaa atcaggagaa tttaattggg aagatgaaat
    72781 tgaattttaa attacttttt tcttgatttc attaacttgt tttccacatt tattttattt
    72841 acacttacca agattttatg tcacatatac atataatatt aggctgtatt atataataca
    72901 acctaatatt atataataaa tttctatttt tcccttaaat cattcacatt ctttctaagc
    72961 tacataagat ttttctatta tttctttttg agtttaattt agcattatgt tgaggaaaaa
    73021 acatttcatg cattttaata aattaaattt ttcttttatt ctgcgatttt ataataatca
    73081 atttaactta aaaataatac ctaactattt taactatgtt aaactagtaa atgtaaccac
    73141 ttatatgtta caattttata taaacatcaa atataaaaaa ctatataaat aaatgacaca
    73201 tagtgttata tttttttata ccaatttagt tatttttcag ttacagattt aataatagtt
    73261 aatagtaaga cataatattt ttatgccctt tattgattat gtattttctg ttatctgtta
    73321 ttatcatcaa taataaacat aagggggtat atattatgaa attgtattta agtgctgata
    73381 tagaaggtac ttgtggtatt gtaaattggg atgaaacaaa acttgaatgt gaattttcgc
    73441 aacactatag aacacaaatg agtaaagaga taacagcagc atgtgatgga gctactcaat
    73501 ctggtgtaca tgaaatactt gttaaagatg cacatgacag tggtagaaat attaatccaa
    73561 atattttacc tgaaaacgtc aaaatactta gaggatggac caaagaccca ctagttatga
    73621 tggcaggaat tgatgaaagc tttgatgcat gtatattcac cggctatcac tctggagcta
    73681 cttgtaatgg taatccactt tctcatacta tggatattga ttatgactat tttaaaataa
    73741 atgatgaaat agcatctgaa tttactataa atgcttatat tgctgcatat tataatgttc
    73801 ctgtagcatt tttaagtgga gatgaaatgc tttgtgagag tgcaaaaaaa ctaaatccaa
    73861 atatagtcac tgttcctgtg tcaaaaggaa ttggaaatgg ttcaatttca atccatccaa
    73921 accttgcact aaaaaaaatt gaaaaaggtg tcaaaaaagc tttatctgga gatttatcta
    73981 ggcacttaat aaaattgcca gataaattta agatagaaat aaaatttaga gaacattata
    74041 aagcttttaa ggcctctttt tatccaaata tgaaaaaaat agattctcaa acagtactat
    74101 ttgaaacaga ggactattat gaatttttaa gaatgttatt atttatataa atttcatatc
    74161 ataaattaag gagttgatta agataagtaa taaaagaagg attcctttag gcgaatttat
    74221 ttctgtattt ttattttttg ctgttttttt tggtataact ttttgtattt tcacggttat
    74281 aggaattggc ttcttatcat tcttaggatt tgaatataaa tctcttggag ctgtattaat
    74341 tttcttttta atatattttt gtataaccac tccaattgat tttctatgca ctactatttt
    74401 agatatattc agatatgtaa acaaattacc atactcaata tataaacttt gcgaatttat
    74461 aattgatttt atactaactt ttctagctat gaacataatt gataccttta tggattcagt
    74521 aacgattcct ttaagtacag aaatcttatt cgctttactt tcttatcttt tatcagaatg
    74581 tatggatttt tttgataggg ataagaaaaa accttaataa aaaagataga ttccttaata
    74641 gaacacatat tttcgtattt ctattattta atctatcttt attttattta ataaattttt
    74701 attaattaaa atatagtttc ttctatctcc ttagtcattt gcttagcact atcaaaaaat
    74761 tcttctatat acactacttc atcactgacc ctagaatatt ctgctgcaaa tgccattaca
    74821 tgactttgta tagcttcttt tgctgctact ctaccctttt ctagttcttt atttgaaact
    74881 aatttaataa attcagctat aagatttcta tcatattcct ctaccatatt ctgttgattt
    74941 gatggattca taactatttc ttcgtttttt ccaaattctt taattcttat ctcattttta
    75001 tttaaatccc caccaacttc accatggcta aacattaact ttatagttct tccattttct
    75061 ttagtaaatg cacataaatt aaaagtagcc gtcactccat tttcaaactg tagtatattt
    75121 accatattgt ctacaacatt attatcacat ctgtaaacac atcttccata tggacttgtc
    75181 ttaagtatat ttaatagatt ctcttcagtt ggatttatgt gaacagctct atttatactt
    75241 ctatcttttt ctaaataaat tctctttgct gaatatggac attttttttc aactaaacac
    75301 tgaagacaat tttgtgccat ctctccacta gcattttggt tattaagatg ctttaagctt
    75361 ccaaatgcag atattttttt gcatctactt cctactaaat ataacaaaat atccatgtca
    75421 tgacaactct ttgctaaaat taaagggctg gtttcattgc tatttctcca attccctcta
    75481 gtaaagctat gtgcaaaatg ccaatatcct atattttcat tatattgtat actaactagc
    75541 tctcctaatt ttttgctttc tacaatttct tttaatttat tataaaatgg agaatatctc
    75601 agtacatggc aaatcataaa aatcttatct ttatacttat cacacaagtc atctatatgt
    75661 accagaccat ctaaactatt agacattggc ttttctaata gtacatgata acctttttca
    75721 agagctagtt ttgctacatc ataatgtcta tcatcatttg tagctattat tactgcatct
    75781 gccatcttgt catgtttaaa aaagtcttct aaagtttcaa atacattttt actatctagg
    75841 ttatattttt gtgtaaatag ttctcgtctt ccttttttag gttctgctac agcaactatt
    75901 tcacatacat cagaattttc ataaatatat ggagcatatg catacgttcc tctattacct
    75961 gctccaatca cagcaacttt cactttttcc atactttaat ttatcccctt tatattattt
    76021 atactactct attatagtct atttttacag acatttggat atttttaata aaagaaacag
    76081 cagttataat ttttcaattt taactgctgt tataagttaa tataccaaac atttttaatt
    76141 aaattttctt taattttaat acaaagactt aaatattcaa tacaaattat aaaaacactt
    76201 ttatctagtt tacttcttct tttctttgtc taatttatct aacttcttat tgtataaaaa
    76261 catataaaat gctgccgaaa atactattaa atatccaaca acacttaaca tatctggata
    76321 gacattgaat aagaatatac ttaaaattgc tgaaaagatt atattactat agtcaaatat
    76381 agagatttcc ttagcaggtg catatttata tgctagagtt attccaaatt gacctagact
    76441 tgcaaatact ccacctagta atagatatat aagttgcata agggtcattg gttcatatac
    76501 tgcaaaagca attggcccta cagtaactaa tgaaaaaact gaaaagaaaa atacaattgt
    76561 atagtaatct tctctatctc caagaactct taaacaagta tatgccattg ctgcaaatac
    76621 agctcctgca attcccccaa gatatggaat tacttctaca ctaaatgttg gttttattat
    76681 gaataaagct cctataaatg caattataat agctcctatc tgctttacat ttattttttc
    76741 ttttagagca attgcacaaa atattactac aaggaaggga ctcattttat ttagcatatt
    76801 agcatctgaa agcatcaact tgtcaattgc atagtagtta aatataactc ctagagttcc
    76861 aaatattgac ctatataaaa gtacttttaa attttctttt ttaccagtta gacttccttt
    76921 atgttttatg ataagccaaa aagctattat agctgatacc agatttctaa agaacacttt
    76981 ttgaaaactt ggtaaatctc cagctagctt tacgaatgca gacatcattg caaagccaag
    77041 cgctgatgct attataaaca ttataccttt tattcgattt gatttgattg tgctactcat
    77101 acgtacctct tttctatata aatgtataaa gccatattaa ttaaaaactt agcttataca
    77161 ttaaataata attatctaaa tattccaatt tatactataa ttaaaagtgt aaactatgtc
    77221 aagtaactaa taaatctttt caattaataa caataataat tatagctaaa aagttatatg
    77281 tttttatgga ttattatcag aatatataat ataattttat atagtataga ctttttttaa
    77341 tttattattt agatttttaa tagatttttt aactatggag gtatttaaaa tatggaaata
    77401 aagagatatg aaggaactgg aagaatgagt agagctgtag ttcataacaa tacagtttat
    77461 ttatgtggac aaactcatgc tgaaggagga gtaattgaac aaacaactga agttttagct
    77521 aaaatagaag atttattaaa caaatatggt tcagataagc aacatttgct atctgttact
    77581 atttatttaa gagatatgaa agactttgaa gctatgaact ctgtttggga tgcttgggtt
    77641 gaaaaaggat ttgaaccttc tagagcttgt gttgaagcta gacttgctag agagcatttg
    77701 ttagttgaaa tgagcgttgt tgcagctaca aaataatcaa tttagcttat aggaggctat
    77761 ctcaaaacag agagataagc ctctttttca ttgttgaaat tatgaaaata tatttgattt
    77821 cgtataaaag aaagtgtctc acgaactaaa aaattcattt tgagacacct cctcactatt
    77881 taatctatat aaatttactt attctctatt ggcaatatca atttagatgg atatttacct
    77941 ccatggtaaa tcgtattctt tgcttctata tattcaatac tattatatcc ctctgtcgtg
    78001 ttgctatttt ggaaaataaa gtttttagca ctagacgtta tatctagtct aattttatga
    78061 ccaactttaa acgtgtttga tatttttgaa gttataatcg taaacttata aatctctcct
    78121 tcttccataa actctgactt ataaaaacta tttctaaatc tagcactaag tataccatca
    78181 gctaatttaa ttgaatttcc atctaaatcc acgtccataa tttttataac ccagtcagta
    78241 tctttggcag aacttgatgc aaaaaactct aactttatat cacctgttac agtaaattct
    78301 tcactaaaag catctgatgt ataacacaac atatcacttc ttttttctaa atctttgtag
    78361 ttatttggaa ctccaacttc attctctgac atatcaatta gttgtactga tgggtctttt
    78421 ggattatata tataactatc atacttttct tctaaatcat tatcaaatac taatctacca
    78481 tttcctaaag atgtgttagc atttccatca cttattagat acatactttt atctatctta
    78541 tttattattg gccaattttc ttctgtcttc cacttattag aacctacaga gtaatactct
    78601 actggagcag tcgtatctat gttattttct atacctttta agtatttatc aaaccataat
    78661 agataattat aatccaaatc atatcttaat gaactatttc ctaaagaaat accatttata
    78721 tctcttaaag tatttgaatt atgcatccat ggacctagaa tagcctttct ctttcctttt
    78781 tcatagtcct ttataacatc taaggcctct gtagttccca tactattatc atcataccac
    78841 ccagatacaa ccaatgcagg tacatttatt ttatcttttt gtaaatgcca atccatcaaa
    78901 tcccaatact catctttttc tactctcttt aaccattctt ccagaaattc aattctatat
    78961 ccaagagctt caaaaggtat attttctatt ggtcgtatgt ttaaaacatc atcccaatca
    79021 tctcttacca ttttgcttct atcaacttta tttcttgata ccataaatgc ccatgcaagc
    79081 ataccagata caaaagctcc tccttttctt ggtatatcaa taaaagggct tcctgatgtt
    79141 actatactaa ctaaagcttt aagatgctta ttgcctgaag atgcagctgc ccattggaca
    79201 taaccaagat atgatgctcc aagcattcca actattccac ttgaccattc ctgtgatact
    79261 atccaattta tggtactatc tccatcttcc ctctcatgaa tcataggttc ccacttacct
    79321 tctgattcat ttcttcccct aacatcttgt attacaacag catatcctct ttgtacatat
    79381 ttataatata tttctttatc attttctttt ccatatggag ttctcataag aattgtcggt
    79441 gcttttttgg tagaatctac aaaatcaggg agatatacat ctgtagaaag ttttatacca
    79501 tctttcatat caatcatata atttccacca aatcttatag aatatatctc ttcattttta
    79561 tgagtttttt cccattcttt taatacagta tactcttcat atccatccat aattaatata
    79621 gtacaagttt ctctggataa acagataaaa cctactattt tattatctac aataattata
    79681 tctagtggga actttttgtt tctttgaacc catatatatt cattaagttt agaatgcgtt
    79741 tctcctaagt tatttataac tgtgtcttta tctgtgttta ctaagctttt agtatataca
    79801 tcaaagttat taaataaaga ctttaaatct atttttgtaa gatttaaata gtatgtattt
    79861 tcttctttgc ttattggttt taaactttct attttatttg taaaaggatt caacttttca
    79921 attaataaat ctccatcaaa gattacattt ccactgtata gtccagatat gtataattta
    79981 aattttatca attaaactcc cccctataat cctagagaca tctttattgc atatgccact
    80041 gatatacctg cataatttcc taatactcca ccaattactc ccattacgac tgctacactt
    80101 acaagcgaat tccactttgc agaagcagct actaaagctg aagtaggacc atcagcaatt
    80161 gctcctacta tagaaagtat tacatattga tactttatct ttaaaagtct agttatgcct
    80221 aaatggaaaa caaatgaagc aaaaattatg ctaaaacagt aaagtgttat agtaaaagtt
    80281 gaacctaaaa actcttttat atctactgaa aaacctattg tacataaaaa gaataatgca
    80341 acaaataatc ctaaatctaa atttcccttt agtttcttta ctggctttaa ttgagcaatt
    80401 ataattgaaa ttgttgtaac taaaagtatt cttgctgcac tactaaaact tgaattgaaa
    80461 tatccagcaa gtattgttga aacttctgta acaacaaaac ctatagccaa catccaagct
    80521 atatctttaa tactccattc ttttgactcc ataaattctt cattttgaca atcttctaat
    80581 tctgattctt ctacatgata tggccaaagt tttttaaact tctttgaatt ttttaatatt
    80641 gctggtagag caaacataaa tatcaatgtt ggtactccaa ttacatagtc tgctgcattt
    80701 gctgctgcaa gagtttgtct acttacatta agacctgttc caatagctgt aagattagca
    80761 cttccaccag tgtatgtacc tacaaacatt ccagcaacct tccaaccttc tgatattttt
    80821 tctgcaaata ctaatccaaa taaaaatgcc atgatactta cagttaatac agctacaaaa
    80881 attgcaatta aaggttctct tgataatttt gtcatttctt ttaagtcaac actcatcaac
    80941 attatagtca tagaaactgg aatagcatat gttgaaatag ttccatataa ctcagtactt
    81001 actggaacta cttttaagtt tgaaagtatt attcccatta tgattattgt aagtgctggt
    81061 cctaagcttt taatggcttt gtatctttgt aagtaaaaac ccaatgcaat cattgatgtc
    81121 attacagcaa gtatactacc tggatttgaa aaaagtgtat tcatatttaa cctccaaatt
    81181 tatcataagt ttacttctat tcctaaacct ggtttattga caagattcat aatatctcca
    81241 tccattacaa atcctccaga tataccttct aattcttcac aaaacataaa actatcaagg
    81301 tcagcttctg ttatgttctt tttagatgct attaaatttg ctgctgctgt tataccaatt
    81361 ctcgtttcca gcatacatcc taacatacaa tttactccac ttgcctcagc tatgttgttg
    81421 atttttatag caggatatat tccacttgat ttcatcagct taatattaaa tgtatcaact
    81481 gcattctttt ttatagcctt aattgcatct attggtgaat gtaatgattc atctatcata
    81541 atttttgtat tacttttatt tcttatgtaa gcagtaccat ctaaatccca atgtggaagt
    81601 gcttgttcaa ttgcatcaac attaaattct tctaactttt tgatagtatt tatactgcta
    81661 tttacgttcc atccttgatt tgcatcaatt ctaattctta tactctctcc aacagctttt
    81721 ctaattaact ttacagcttc aatatcgtct tcaggattta tacctgcttt aagcttcaat
    81781 atcctaaaac cttcttttac tctttctaaa gcttctactg ccattttttc tggcttatct
    81841 atacttatag taatatccgt ttggacttta ctatcaaatc ctccaagaac tttataaaga
    81901 ggtgcattca taatttttcc tttaatatca tataaagcta tgtcaatagc tgcttttgca
    81961 gaagtattac ctataataat tccatccatg atggtatgta tggtttcaat atctagtggg
    82021 tctttgccta ttaactcttt tttaaacata agcaatactg aaagaacatt atccaaaact
    82081 tcacctgtaa ctgctgcaag aggtgctgct tcgccaaatc cacaataccc ttcatcagtt
    82141 tcaattttta aaattatact ttctccatac tcaattactc caaatgaaac tactacaggt
    82201 ttttttaatt taattctaag cttttcaaat ttgatatctg ttatcttcat attaccctcc
    82261 ttattttttg aagttataat tcaattttta aaattttata ctttaaatta tattattact
    82321 tcaatatata tgtcaagata atttactgaa aatttactct tttccaaaat ataatgtgat
    82381 aatcttaatt caattaatac tcttctatta aattttttta ttattatttt ctttgtatta
    82441 atttaacaat aattcatttt catagacttt tatttggatt taattaaatt ttaattgtca
    82501 aaatctacta tgtattctta ttgccactac ttctatgttg tgctataatt actttgtttt
    82561 aagcgaatat tttatattaa ttttattatt tggaggttct tatgctaggt gaaaagatga
    82621 gaaatataag aaaaagcaag aaaaaaacat taagtgatgt ttccaaattg acagatttat
    82681 ctataagtta tatctctcaa atagaaagag atgctattga accatccttg tcttcattga
    82741 gaaaaatcgc tgaagtttta gacactcctt tatatatgtt tatggatgac aataatactg
    82801 atgatttagt cattagaaaa gaagatagag ttatgatgaa atttccaaag agtgaaatgt
    82861 tttacgagat agtatctcca atgcctacaa ctgagtttac accttcaatt ttatttgtag
    82921 agtttgaact taaaccagaa agtgaggatg ccaaagatta tatatatcat gcatcagaag
    82981 aaattatggt ggtaacgagt ggtgtggttg atatttgtat gggtgaaaag gtagttagat
    83041 taaatccagg tgactcaaca tttataaaag ctaatgtacc acataaaatc attaatccaa
    83101 gtaaagatac aatagctcgt ggatatggag ttatatcacc tccaatttgg ccaataaaat
    83161 ctaaataaac tcaatataac acacctactt tttgtagata atacaataaa tttaaatatc
    83221 ggttttattt taaaattgaa gtatttattt aaatttaaaa tatttactca aactaaaaaa
    83281 atagctattt gactaatcta aaccatctta attatggtaa atagtaaata gctatttgta
    83341 agttatatta taaattataa taaaaattgt atttgttaaa attaaattaa actgctatat
    83401 catttaatac ttttgccttt acaactctta tatttttcat actcttgtag atatcttgaa
    83461 tcttatcttc ttgctctctc aatagtctat gtgcttcata tatatctaca agttcaaatt
    83521 ttactacatc atttggcttt gcttgtgcta acttatacaa atctacactt ataacgttcc
    83581 ctatcttagt atagccacca ctagtctgtc tatctgataa cattataatc ggttttccat
    83641 gaccaggtac ttgtatagct ccataagaaa taccatcaga tataatatct gctccattaa
    83701 ggtgctttat actctctcca tctagtctac aacccattct atctatttca ttcgtaactt
    83761 tgtatttatt tgataaaaat ttctctactt caccgttaga aaaagcatca aattgaggac
    83821 cttttacaat tcttagtacg atttctgaac tataagttgg aatatatttt gaacttaatt
    83881 ttttatttat tgtaaaatct ttttcctgaa taaaagtatt tatataatct ccttttttaa
    83941 gtgctctacc ttcaaatcca ccaattttag ctcttgtata agttgactta cttcccattg
    84001 caagtggaac atctattcca ccagctattg acacataggc tctagcacct gatttcacac
    84061 ctctaaatga taatacatca cctggattta tttgatatga cctccagttt tgaatttctt
    84121 ttccatttat tttagcccct aaatctcccc cagttactgc tatttgcgta tattcatcaa
    84181 aggtaattgt aggacctaac attaaaactt ctaaagaagc ctcatcttca gaatttccta
    84241 ctaatatatt tcctactcta tgtgcatact catccattgc tccacatcca gatacaccat
    84301 attgaccata gccaactcta cctctgtctt gtattaatgt ttggaaacct cctaattcaa
    84361 ctttgaatcc catatatacc actccctgta ctataacgat atttaaatac ttaagttatt
    84421 tttttcgact tctataaatt catctaatgt tattggaaca aattttataa agtctccagc
    84481 tctaagcaaa atctgttctt ctctattttc atcatataat tttaaaggtg tcctaccaat
    84541 tatttgccat ccaccaggac tatcaatagg atatacacca gtctgggaac ctgctattcc
    84601 aacactccca ccataaattt tagtccttgg cacttctaat ctaggtgtag ctattctttc
    84661 atccatacca cctagatatg gaaatccagg agtaaaccct agcatatata tcaagtactc
    84721 tctacttgtg tgtattttta taacttcatc tacagtgaga ttattgtagc ttgcaacgtt
    84781 tttaatatct ataccaaaaa cctcatcata acatactgga atctcatgta ttttaggttt
    84841 tggtaatact atactttcca aattatcttc tatttttttt aaattctcaa tcaaactatc
    84901 aaaatctatt tctaatggat tataacttat cataagtgac ctatatgttg gtaccatttc
    84961 tgttacaata cctttaagat tcgatatttc tattgctctc ataaatgaaa ttactttttt
    85021 gtttatatct tctgatatct catttccaaa ttcagcaacc actgccttat cccctgatat
    85081 caagtatcta gtttccataa atgtcacctc ttctaaatta agcaaataaa gcacctaggc
    85141 tgctaagaga agttattcct gtatatgcag atattaaaac tactattaat ccaaatatta
    85201 aaagccatgt aggatgcttg taatctccaa caatatcttt tcttttagat gctataagca
    85261 taattcctaa tgtgattgga agtatcaatc catttaaagc tcctgctaaa attaataaag
    85321 tagctggttt tcctataaat gccattataa gtgttgatat tgctataaat gctattataa
    85381 aatatttttc atatttatct ataaaaggat ttagtgtctt taagaaagaa actgatgtat
    85441 aagcagctcc tataactgat gtaattgcag cagaccataa tacaagtcca aagaatttat
    85501 atcctattgc tcctgcacta aatttaaaag ctgaagcagc tggattttct gggtcaagtt
    85561 gaagaccttt tgaaaccact gccagtattg ctaaaaataa aagaactctc atcattgtgg
    85621 caactaatat acccaaaaga gaagatttag ttatttcttt tatattttct tctcctgtta
    85681 ttccaccgtc tattaatcta tgtcctccag caaaagttat ataacctcca acacttcctc
    85741 caagtagagt tattattggg aatatcagtc cttttggatt ttctggtttt accattcttg
    85801 atactgcctc tccaacagga ggatgatttg atattgctac atatccaact ataattatca
    85861 ttcctaatgc taaaaattta gttatcttat cgactagaga atttgaattt tttgacataa
    85921 atacaaatat ggctattaat ccacttaata cagttcctaa tgtcatattc atattaaaca
    85981 ttacattcat accaagtgca gctccaccaa catttcctat attaaaagct aatcctccaa
    86041 gagctactaa aaaagctact aaataaccta atcccggtat tattttattt gctatatcct
    86101 gacctctaag tcctgataca ccaattactc tccatacatt tacttgagcc cctataaaaa
    86161 ggattgttgt aattaaaatt acaaatgaaa aattcggtcc aaaatcttgg gtaaattgtg
    86221 cagtctgagt taaaaaccct ggtccaattg ctgatgttgc cattataaat gcagccccta
    86281 taagtgctcc gacatctttt ttatttttag ttttatctgt aatatttttt gtactcatat
    86341 tttatctccc cctcatgtta tcagtcttat actatgttct ctgacgaaca aacttctatg
    86401 ttttctaatg gacaaacttc tatactttct aattcaaaac gctttcttat ttctttgaca
    86461 aactctattg cttttggatt gtccccatgt acacatatag aatctgcttt gatatgtata
    86521 acttcacctg ttaaagtttc tacagttcct tcttttacca tcctaacaac cctatctatt
    86581 gcatgttttg tatcatgtat aactgctcct tctacatttc ttggaaccaa aaaaccatta
    86641 ttatcataag ctctatctgc aaatacttca tttgcaaacc taagtccaat ttctttagca
    86701 gaatttatca tttcactatt atatagcccc aacagtataa tatctttatc gacttcatat
    86761 atagcttcac aaatccccat agctaactct ttatctttag ctgccatatt gtataatgct
    86821 ccatgtggtt ttacatgttg tatattacat ccatttgaac ttgcaaatgc cattaaagca
    86881 cccaattgat attttgtata atctttagct tcctgctttg ttattttcat ctcacgtctt
    86941 ccaaatccta ttaaatctag gaaacctgga tgtgcgccta ttttcactcc atttttttta
    87001 gctagctgta ctgttttttc catatgacta gggtcacctg catgaaaccc acaagctata
    87061 ttagctgatg aaatatattt taaaacttct tcatctaaac caatcttata cgttccaaaa
    87121 ctttctccta aatcactatt taaatctact ttatacaatt tatgacccct ccttgctaac
    87181 attttgatag aataagtagt tttaattttt aaattttgtt tattttatat attgcatgaa
    87241 atattttatc acttgtattc aattttactt ttgcaactat tctattgcat ttaattaata
    87301 taattttacc atttaaggaa tatttttgca attattttaa ttgaacattc atttgtattt
    87361 ctttttcaaa aaatcttttt accatttttt agttaataat taattatttt cacttaaaat
    87421 aagggcttta accttcattt ttaaagtatt tttcattttt aatcacttta tatgcaagac
    87481 agaatcattt ttcttcattc atttgtttct ttcatctata taattatcat tctttgtaag
    87541 taaaatatct ttatattttt ataattaatt ctttatatag ttttaagtat aataaaatca
    87601 tgtatactaa atgcatgtta aaatattatt ttaaaacatg cacaatattt gtacatattg
    87661 tagacatata aacctataaa ttatacaata gtattgttaa gattatatat ttttttaaca
    87721 taaattttgt attgggggaa aaacaatgga taaaaactat acgatgccaa tataccaaaa
    87781 aatagcgttg gatattgcaa ataaaatata cacgggtgaa atacaagagg attcagtact
    87841 atttggacgc tctgttttgg ctggtaaata caatgtatct ccagaaacga taagaagagc
    87901 tgtcaaaatt ttagaggaca ttggcgttgt taaaagcata aagggtaaag gtgttattgt
    87961 actatctcca gacaaagctt cttcttttat aaaaaaatat agagatatta caaatatatc
    88021 atcatataaa tcaacacttt ataatttaat agatactaaa tctaatttag aaaatgaaat
    88081 attagatact ataaataaaa ttttagacta ttctaacaga cttgaaataa tcaatccttt
    88141 agtgcccgtt cagttcacca taaattctaa ttgcaaatat attggtcaaa cagctgcaca
    88201 aactaaattt tggcaaaata caggtgctac aatagttgca attaaaagag gtgaagaact
    88261 tataatatct cctggaccat atattgaatt tttagaagga gacattctct tagtagttgg
    88321 tgaccaacac atttacaatt ctataccaat gtttttatat gaaaacgaaa aataaattat
    88381 ataatttagt atgattatat aaaaatgcaa aattaacaac aaaaaaagag cttcatattt
    88441 tacataaagc tctttttaaa ttcaaataaa tttaactttg attaattttt aaatatccaa
    88501 ttcatcttct ttttcccagc ttaaagctct cgatacagct tttttccatc ctttatataa
    88561 tttacatctc ttctcttcac tcatatttgg attaaactct ttttctactg accactttga
    88621 agtaatttca tttcttccaa tataaaatcc aacagacaac cctgctaaat aagcagctcc
    88681 taaagctgta gtttctacta ttttgggtct atctatatct acatttaata tatctgattg
    88741 aaattgcatt aaaaaattat tattacttgc tccaccatca acttttaatg attttagttt
    88801 taattttgaa tcgttttgca ttgcttctaa aacatccttt gtctgataag caattgattc
    88861 caatgtggct cttactatat gttctttttt tgctcctctt gtaagtccta aaattgaacc
    88921 cctagcatac atatcccaat atggagctcc aagacctgta aatgctggca ctacatatac
    88981 accattagta tcctctaccc tatttgcata catttcacta tcttttgcag attcaattat
    89041 ctttaattca tctctaagcc attgaacaga tgctcctcca ataaatatac ttccttctaa
    89101 tgcatatgtt acttttccat caactcccca agcaattgtt gtaagtaacc catgcttaga
    89161 tttaactatg ttactgcctg tattcataag caagaaacaa cccgttccat aagtattttt
    89221 tgcagtacct tcttcaacac aattttgacc aaataatgct gcttgttggt ctccagcaca
    89281 tcctgcaata ggtattttag ctcctgataa catgcgctca tctgtatgac cataaacata
    89341 gctagaaggt tttactaatg gcaacatgct tattggtatg tccaattctc gtaatatatc
    89401 ctcatcccat tctaaatcat ttatattgta catcattgtt ctagatgcat ttgagtaatc
    89461 tgttacatgt acttttccac gagttaaatt ccatattaac catgtatcta tagttccaaa
    89521 taataactct ccttgttctg ctttttccct agctccttct acattatcta atatccattt
    89581 tacttttgtt gctgaaaagt atgcatctat taaaagacct gttttttctt ttattgattc
    89641 ttccaatcct ttatttttaa gttcatcaca tatttctgac gttctcctac actgccatac
    89701 tattgcgtta taaataggtt taccagtata cctactccaa acaaccgtag tctctctttg
    89761 attagttatc cctattgaag caatttcttc tggtcttata cctgctgttt ctataacttc
    89821 tctcattacc ccactttgtg acccccatat ttccataggg tcatgctcta cccatccagc
    89881 ttttggataa atttgattga actctttttg tgcaattttc actatttcgc cttttttatt
    89941 aaatagtata gctcttgaac tggttgttcc ttggtctaat gccattacat acttcttttc
    90001 catcaccata ttctccttat catataatat ttaatttatt aaaaagaaaa atttaatatc
    90061 acatatttca ataaataatc atacttaaat acaaatttaa tataatagat atttagtaag
    90121 aagacactta ttttctatca tatctatata ataatattat acattatagc ttacatattg
    90181 attaataaat tttaaaggag tataataaac agtgttcata ataattttaa taaaagaggt
    90241 ggtaatatgc caaagatttt agaaaatgta aaagaagata tattaaaagt gtctcgggat
    90301 atgattttag aagaagatta ctcgaatatt agcataagga aaatagctca aaggtgtggt
    90361 ataagtgcag ggacagtgta taattacttt aattcaaaac aagaaataat agaatatatc
    90421 acaaaatctg aatgggattt attgataagg cgaattgaat actccaataa aaacactgaa
    90481 gattacataa aaaaactaaa cattattttt actgaaataa gaaattttat aaacaaagtt
    90541 cataatatcc aatacaatga ctttttaaac acttttgaaa cagagagatt ttttgaaatg
    90601 aaaaaacaca aagacgactt tcatgaacag ctttcaaata aagtatatga agctttagaa
    90661 aaagaaagtt tttttaataa tgacaaatta gtatgcaata tcataataaa aatgtttttt
    90721 tcatattcaa catatcttca tatagaattt gaagatttaa aaccctatat tgaaaaatta
    90781 atacattaag gtggtgttta ccttgaatca taatactagt attaagaaca aggacagtaa
    90841 tccaaaaata tttttagtac ttacacttta tctattaggt atatttatgg gagctattga
    90901 tactggaata gtatcaccag caagaacgat tatacaaaat agccttggag taaatgaaaa
    90961 aacgggaatt tggatgatta ccatatacac attaacatac gcttctgtaa ttcctatctc
    91021 tggaaaatta gcagataaaa taggaagaaa atatgtgtat ctagttagta tatttctatt
    91081 tggtagtggt tcattaatat gtggattatc atcactattt tccaatttct atattttatt
    91141 aattggtcgt gttattcaag caattggtgg tggtggaatc atgccaattg ctacagcaga
    91201 atttggaact accttcccag aaaacaaaag aggcatggct ttaggtttag ttggggcaac
    91261 atatggtatt gccaatattt taggttcaag cattggtagc acaattctaa gtatctttgg
    91321 aactcaaaat tggaagtggc tattttttgt aaatcttcca atttgtttaa tcatacttat
    91381 tggtggagtt ttctgtatta aaaacaataa gtctgaatct aaagaaaaaa tagataagct
    91441 tggtacattg atgttgatat gtataatcgt atcactatta tatggtctta tgaatataga
    91501 cttttttaat tttaaaaatt ctatacaaga tatatcagtt tatccatact tattgacatt
    91561 tattgtactt atacctattt tcatatttat tgaaaataga gctaaagacc ctattttaag
    91621 ctttgaatat tttttaaatc cgagaatatt aatagtactt attttatctt taattgttgg
    91681 tattggaatg atgggtatgg tattcgttcc acagtatgct gaaaatgcat taaagataaa
    91741 tgctggttct ggtggatatt ttgtagctat attgggatta tttgcaggta ttgctgctcc
    91801 tttaagcgga agacttattg acaagtttgg ggcaaaaaaa atactattac taggattttc
    91861 tgtatctatg ataggctctc tttacctagt tttaattgct ctaaaaacca atactgtatt
    91921 tagtgtatgt gtaagtttaa tatttatggg attaggaatg ggatttacta tgggaactcc
    91981 tctaaactat atgatgttat caaatacaag attagaagaa tctaattcag cacttgcaac
    92041 attatccttg atacgctcaa ttggtacttc aatttctcca gctataatga ttggatttat
    92101 agcacatgca ggattatctg tgcaagataa tattatggac ttagttggaa agccctcaac
    92161 tcctaaaata gttcaacttg aagaacttga aaacatgata gatgacttaa aatcagaccc
    92221 tgaaatggca aaaaatttaa aaaatgtctc tatcccaaat atgaatgata cttcaaatat
    92281 aaatatggac atgacaggtg gtaaacttcc aaaatcctta cttaataaag ttcagtcagc
    92341 agatacaacc aacattacca atataacaaa agaaatatca acaacaatgt ttgatgaaaa
    92401 agttccatct ataattacta aaatacagaa aaatgtacaa aaaggaatag atggaacaca
    92461 aagtggaata aacggtattg aagatggtga aaataaacta aatagtggta ttaaaggagt
    92521 tcaaactggt attgacaata tggtaaaagc tagagctggt attaatcaag gaatagatgg
    92581 tgtaaaaaaa ggtattgctg gtgttgataa aggtataaaa ggtatggaac aaggtcttga
    92641 aaaacaagat gaggccatca aggaacttac aactgcttat aataaaatac ctactacaga
    92701 aaaaactcct actgataacg aaaataactc aaatgaacaa aaccagagta ataccagtaa
    92761 ttctgaatca gatgacacta agaatgattc tacagaaaat aagaataaca attccagcga
    92821 gaataaacca aatgtaaatg aacaaaaaga aagtttaaat gctcaaatac agcaactaaa
    92881 aaagacaaga gatgacttaa atacaaagtt acaaaaaaat aaaactcaaa agaacgaatt
    92941 aagtaaaaaa ctaagatcaa tggaatctca aaagaaagag ctacaaagca agttaaataa
    93001 ttctataagc caaaagaaag acatggaaaa aagccttgat acaatgcaac agcaaaaaaa
    93061 atcactccaa gcagttttag caaagacaca agaggtaaaa actgaaatac caaaggcttt
    93121 tgataaatca aaattggatt atataaattc catagaaaat aatagaacaa aaatagaaaa
    93181 cacactacaa tctactctaa actcaggatt taaacagatg tatataacag tattctgtgt
    93241 aaatctacta gcatttataa tattattgtt ctataaagaa aataaaacta gataaaagag
    93301 tgttatagta ttatattgta aatttatctt attcttaaat attttattct aaagaataaa
    93361 ttcataaaat ttttgtaatt gattaatata aattacaata taatactatt tttctcttaa
    93421 tctttttctc ttttacagac aatcaaaaag caatcttagt ttatcgaaat aaatttatac
    93481 aatctattca tacacccctt tacattttta taacaattaa acctattgtt atatatacaa
    93541 atcaaaataa accatatatt ttcaactata atatgttaaa atcatattat gagcatatta
    93601 atttaagcaa aatgtcattt agactttaat ttagtagttt tatattataa atttatatat
    93661 ttttaatttt aaatgtcatt tagacattac taataaaaag aaaggagtgt attttgtgga
    93721 tactttagga aaaagaattg cttatttgag aaactccaaa aaacttactc agcgcaaact
    93781 tatggatatt ttaaaatttg aaaacttagg caagtatgaa acaggagata gaaaacctaa
    93841 ttgtgatata ctaatgtcaa tagctgatta ttttaatgtt acgactgact ggcttctcta
    93901 tggtaaagag aaggtaaatg tcaatagtag tgtaaaagaa gataaagaag attacttaca
    93961 tgttactaat gatgaaatga cgatattaaa tctatacaga caactaaacg aacgtgataa
    94021 aataaaaata gaaggaatac ttgaacttaa gatatctgaa tataaagact taaaaaagca
    94081 ttcctctaat aataatgaag ataaaatggt ttaaacatac ataatttgat acgattttac
    94141 atcatctatt aaccttcttt ttttgtagta tattactaaa atatggatat tgaattattt
    94201 aaaaacaagt atagtctaat ttcaagcaca tttataatat ttagattatc ttatccatat
    94261 tttagtttaa gtactttgaa aaatataata catctctatg tataacttat attcctaaga
    94321 aatgcattac tcatgttttt aattcttcca acatctttct atacacaatt gtacatcctt
    94381 cataattccc ctctttaaga aggattgaac atgtactaga atatttagtt aaagtattta
    94441 atctttccat atttaagctt tttatattgc tgagtgctgt aataaaatca tcaattgctc
    94501 tacaacactc tataacccca tctgaatcca atttacacac aagaatattc acctacttta
    94561 tatactattt attaatcatc ttctgaatat tctatattaa gtaattgata aattgatgat
    94621 ttatattttt tacctgttct tcttccattt aaaatagctg acaaatagtt ttcattaaca
    94681 cctattttct tcgctaattc cctttgagtc atatttaatt caataagtct ttgcttgact
    94741 tgcactccca aaaaaggtat ccattttttt cgagcatcca tttatcaact tcctttctaa
    94801 gtgatttata tttactttta tattatttta gcttacgcac cccctctatt tagtatatat
    94861 ttttaatatg tacacatatt aagtatataa atttatttaa tactaaataa gattttttga
    94921 ttactttgtg ctaaaattag gatgtaaatt cgtatcatta agttaattat aaagtcattt
    94981 tgaccttaag tcaatggttt ttatgtcatt ttgaccttta atttgaaact atttacatct
    95041 taaaaagtct ttttgacatt aattgaatgg agagtgttta tggatacttt aggagaaaga
    95101 attgtttatt tgagaaaagc aaaaaacctt aaacaatatg aactagaaga aatgttgggc
    95161 tgtgacaact taagtaaatt tgagagaaac attagaaaac caaattatga aatattaaaa
    95221 tctatagctg agatatttaa tgtttcagta gactggctat taaatggaga taatctatca
    95281 cataaatcag atttaatttg cgattcctcc tcaaactatc cacttaatag cataaactct
    95341 aatgaaataa aacttttaaa caactttaga aagttaaatg attatgataa agccaaaata
    95401 gaaggtatga ttgaattaaa acttcatgaa tatgaaaaag agaaggattt aggaaaaatt
    95461 gagtataaca aaaataaaga tgagaaaata gataaataat ttttatgttg cttttgatac
    95521 gattttacat catttctttg ttctaatatt tttatttcat ttattttctt ttttataatt
    95581 ttatgataaa ataattagta tattttgctt tacttgaatg taattattta tacaaaagtc
    95641 aaacataata taaatgtagt aaatttttag tttcaagtaa tatctcgtta ttataactaa
    95701 atatttatta aaattaggag gataaaatgg gcttaagaga caaattcgcg caatcatttg
    95761 ctagatcaaa aactatgagt ggccctgaga aaaaggctaa tgaaataatg ggtaaattgc
    95821 ttcttaagaa agctatatta cctatcgttt taatgttcgt gataataatc gctggagcta
    95881 tgcttaaaat caattcttgg gttacacttg gcataaattt agttattgct gttggtgctt
    95941 tcttctacat aagaaattct agtaaaaagt atcagaactt taaaccttat gttggcaatt
    96001 tgattagttt agagaaaaaa ggtaaaaaag agtacgttgc tattataaaa caaggtaagt
    96061 taccagttaa gttacaaata gcttatggtg gtgaagacct tgaacatatt aagaaaaatc
    96121 aaatggttca aataagttat aatccagatg ctaaaatagc tattttggtt aatagacaat
    96181 aatttaataa aaaaaaggag ttgtcttaaa attgattttt tctaatcaaa tttaaactca
    96241 actccttttt taatttttat atattatttt tattactttt tttaattaat atttttaaat
    96301 attaaatcct tctcaataaa atagtgaact atctacaata ctactttatc ttttcctaac
    96361 aatatataat ctggtgctac tctttcatgt tatacaccgt tttgtaacat accttttata
    96421 tcagtaacat cttccttaat ttcctctaca tctgttttca ttattcccat ttgaacaagt
    96481 atatttttgt ttatttcttg ttgttgtgta gataattcta taaaattttc tacagttttt
    96541 ttatacatgt ctctatcttc ttttttctcc tgcatagtat ttttaaataa tagagcacat
    96601 agtataccta ttgcccctag actactcaat tcggttatta atttatccat tatagcctcc
    96661 tattgtctaa attttttata cttatagctt taatttttgt tgtattctta catcatgcaa
    96721 tattatattt tcaggattat caatttaatc ttctgtactt taaattgtag gtgtaattta
    96781 tagattgaat aaataataaa tatatataca atttctaata taacaaaaaa taagtacaag
    96841 gcttacttat taaagttaag accttgtact ttacataaaa aaaataacta gtatatagtt
    96901 attctaaatt tactattcaa ctggtatttc taattcttta catctaattc taacttgctc
    96961 tctaattact gctggtactt cttctattgt ttttttgcct cttaaaatta aagctacata
    97021 tacttctacc attccactct cacctccaga ttttcttaca ctaaaagtgc ttatattact
    97081 tgcttcattg acagaacttt gatttaacaa catctcatat atttctgcat ttgctataaa
    97141 attatttgtt atatcatcat cttgctttac ttgacctata cttatgtctg agatatcttt
    97201 atactgcatt tctacttttc taccttgttt gatttgttct attttatttt tatcgaattt
    97261 aaacaatttt cacacctcca ttttaagctt gtggctcgtt gttttcagca tcatatctaa
    97321 aaatcataga tggacgtttt atagctgtcc atttatctcc tttttctact atgattttag
    97381 gctgagcact ttttatgttg gcttcttcta attcatagat ttcttggtaa cttgagtctg
    97441 attttttgat ttcaactagt ttcatgtctt tgaataagtc agatttattt atttttactt
    97501 gaactttagt tttatttatt aattgatata taggattgtt ttccatcatg tcatccttta
    97561 atccctcatt taatgttact attaaatcag tgttattttc agtaatgttt atgattgaat
    97621 atactttatt gtttatcatt aaaatagaat ccttttttac tttaagccct gtttctgatt
    97681 taaatataaa catacttgaa tataaatcgc ctgtaggact actggcttta atcagtatct
    97741 tattttctcc taatactatt ttattttgtg gtatctcaaa tataatgcta tttatttcca
    97801 aattagtctt agtagatatt aattcatcat ttataaacat ttcaagtttt tctataacat
    97861 tattaggatc ttgtactaca actctcactt gagatattga tttttcaact atttctatag
    97921 atgctttact tgtatctact tttgttatca tgtatattgt atcatctgaa agctctatat
    97981 ctaaaatatc atttagatgt tcaggaattg gtattttagt aaattcatat aaatcagtaa
    98041 ttgatataga tattttatac atagatttat ttttaccagt tatccataga ctattatcat
    98101 ttttaattac tagtatgtgg tcatcattat gtgacttaat ttctttaaca ttagttaata
    98161 ctttagtaaa agttgttatt attttatctt tttcactttc tcctagtcca aacaatccat
    98221 ttgtattata cccttgagcg tacaactctc cctcattagt taaaacaagt gtcattgagt
    98281 tatatatact tatatcttta acagaaggta atccagtaac cttttgtaac tctcttacat
    98341 cattattgtg accaactccc aattggtact cagtattctt tccatatgac catagagtat
    98401 tatctgtctt aataatatag gagtagttat ctccacaagc aacttttttg acatctgata
    98461 tatttacttc agtaaaagtt aataattcta tatcttcaag agtttgatta atttctttat
    98521 atgaattact tcctattcca tataacttgc catccttagc aacagccaat gaatgtgttt
    98581 ttgatatatc aatatcagat acctcaaatg gcaatattat tgaagtatac ttaaaattat
    98641 ctttaaatat gtttttataa tttatatact tattatttgt ttttatatac ttatcattaa
    98701 acattactag cttttcattt ttcttattaa aaactatttt atctgatgtg ttatctgttt
    98761 taaaatatga atgtagggaa ccttcaagag cttcattttt atcattatca tatctatggt
    98821 gaatacctaa atgattatat ctattatctc ctgttgaaga ataaaatttt ccatatatat
    98881 ctttaataaa tatagtattg taactagaaa atacagtatc aacatctttc tttatagata
    98941 ctttataata tggaactgac atatccctat aagattcatc agatatacca taagtatctc
    99001 tacctgatga tatcaaattg ttattattat ctatataaag tgtattatta gctgttacaa
    99061 aaacatcttt aacatcttcc acactatttg tattattatt atttgctata cttccatatc
    99121 cactaagacc tccaacaaat agtttattgt catttgttaa aatggctgaa gtatatccat
    99181 taactactat tttttttgca tttataatat tattaattac tcgtatcccc tttatatcat
    99241 tagtctctgt tgaaaagaat accctctctt ttttccctgt agtataaatc atattgtcat
    99301 ttgttataaa aaatgtagct tcacttcctg ctgtcacaac agattttaca ttctcaatat
    99361 ttatttttgt aaatgtactt atacttcctt cagtaaaccc aaaatagcca tttacaagtc
    99421 cacatacata gcatgtatta tcatttttaa caatgattga tacatcatta catagatata
    99481 catctctaac accatttata ggtatacgtg taaatatatt cctacttgta gtatcaccca
    99541 atcctaactg tccttttcca ttattacctg ctccatataa aagaccatca ttagttaata
    99601 atagagatgt gtttccatat acagctacat attttacatt ttcaacattt attttagtaa
    99661 atatatttct atttacatta tctcctattc ctaactgacc agaattattt aaaccaacag
    99721 cataacaggt attatcattt tttatcgcaa atgcatgttt actattgtca gtaaatctat
    99781 ttacatttat aaattttata ttatcaatat ttattttagt aaataccttt ctatttatct
    99841 catctcccac tcctaattga cctacatcat ttaaaccaac actgtaaagc atattattat
    99901 tagttaataa atatgtagac tttgaatggc tatatatttc ttgtatatta gaagatattt
    99961 cactactgct attcttttta ttgtaattta tcttattatt taaatttaaa ctactattaa
   100021 ctgatatacc atgcgtaccc ttagagttat atccacatat aaataagctc ttatcagtta
   100081 atattgcaaa tctagtttta tctctactta aatcataagg aggtataaat atatttttta
   100141 tatttttcat taccttttta taattagtgg cattatatcc atcttgtgta tctgaaacat
   100201 ctagttcttt tgcactttca gatatattcc caaaaccata tagcgtgtta gaagataaat
   100261 acaatagagc tttatataaa aatatggctt tatcagaggt aataggacct gaatttatat
   100321 tagatgctgc aatattatta gatgattgat tgttaagata attccttcca tattgatgta
   100381 tataagatga acctccagaa ataagtaaat tatctggatt gacatttttt aaattacttg
   100441 acgattcccc attatataaa taagcaaaag ttgtagaaga tgatgattgt gtacatcttg
   100501 taggataata attatatata taagaatcaa gatatcctgc atatgaaatt ccctgatatt
   100561 gaactctata gcttgaatca gttggttttg tccatgaagt accatggtat ccagttagaa
   100621 aagatccaat gtttgtacaa aatacagtta catactcata tatgataata ttattaattt
   100681 tagtaatatt attcgtgcat gaaactctac tataacttga ccctgatata tttatataat
   100741 accaatcact taataaacct agatttacat tagatccatc agaagtacta aaacctaaca
   100801 ggtaatttgt atttatacca gttgcatata cctttttttc atcaactaca ataaatgttg
   100861 cattatatga actataagca tcagttacat tactaaggct aatctcagta tattgactta
   100921 ttaatgcatt actaagtcca ttaacataac ttgaactctt tccagaagtg tatatttgct
   100981 tattattagt tacaattaat gaaaaccagt ttgataaatc agtatttata acaacttttt
   101041 ttacattatc tatagatatt ttcttaaata catctgaatt agaaggaaga acacctgcta
   101101 ttgagttact atttggtcca gaataataac aagtatcatc atttttaatg tagaatattc
   101161 ctccagaaat attttttgat gctactatag actttacatt agagatactt aattttgtca
   101221 actcatttaa ttgacttggt aagtcagaac ccattccttt gtatctatta tttcctagac
   101281 catatacatc tccattccct aaaataacca gagtacaata aggactaaaa acgacatctc
   101341 ttacagaatg tatatctagt ggaagttcaa tatcctttat ttccatttct tcttttaata
   101401 aagttaattt atcctcagat ttaattaaat ttatataatt actataacta tatttttcac
   101461 tatccatttt cttaaattct acaatgtgca tatcatcaaa aaacgaacct aattgtccat
   101521 aagtattatc tcctgtacaa tatgaatcat tatttgaatc aattagtatg ctatgtgata
   101581 aaccaatgaa aatattctta gctacaatat tttttaaatc tataaatgaa ttatctatat
   101641 tctcagagta atttgctata cctaactgat atatatcatt atttccagca acctttaaag
   101701 tacctttgtt atctataagc atagtgttac catgaccaca tgcaatagtt tttatattta
   101761 cttcttctat cttagtaaat agtgatgatt gaagtgcatt tccaaaacat ttttcctttc
   101821 cacaaccata tatatcatta ttatacgtca ttaacacagt gtgttcagaa ccacaagcta
   101881 tagtcttaac atcattaata gaaactaaac taaataaatc tctattattc ttatctccta
   101941 aacctagttg accttgatta ttaaaaccag tagaatagca tttattgtca ttctttatta
   102001 taaaagctga tttattatat gaaaatacag cctttacatt gtcaacatct acttttgtaa
   102061 atgtatttac atttgcagat gctccattag ttcctagacc taattgacca tacaaattat
   102121 ttccagcaac atataaagtt ccatcattgt ataaaagata tgttgattga agtccacatg
   102181 caatatcctt tacgcctttt atttctggaa ccttctcaaa tgtagaaact gttttcccta
   102241 ctttttctaa tcccaatccc atttgaccat ctgtatttat acctgcgaca agtaattctc
   102301 catctgaagt aagtataact gcatgagatt ctccacatgc aactttttta atattggtag
   102361 atatatttgg tattttcgta aataattttc ttgttgtatt gtcttctccc aatccaagtt
   102421 gaaagttact attatctcca catccataca agatattatt attttttaga ccaaatgtat
   102481 agttacaaca tccagtaaaa aaattaataa agtcataatt atcataccct tcatcaaatt
   102541 catcaactac catattttta tcgccaaaga aattacctct ttgaagtagt ttagttcttt
   102601 tcattataaa aacctcctaa ttatcttatt tcatacgaat atttatttaa agttatatct
   102661 gtctgaccaa ttgaatatgc cctattagat tttgtttcaa caaagttatt atccatttca
   102721 tgtatatatc taactctatt tgcattaaat ggtagcacca cattcttaaa tgtaacacta
   102781 ccaagttctc cagttataca ctttctattt aaatctaact taaggccttc tatagctatt
   102841 atgtttttag cattagttaa ggtatcatac caatatccag cttcatctac atctatttct
   102901 gactctaatt ctaagtatat taagatatct aatacttttt cagataattt attgtaacta
   102961 ttttttaata cagatagttc agtttgtatt tgacctccta ttacatcatc aatagatata
   103021 tttttaattt tttctactac ctcatttata gctcctgata agtttttagc ttctgtagat
   103081 aagagttctt cgccaatttt tacttttatt tcttttatat ttttatcaaa cttatcatct
   103141 aaatcttgaa tatccttttg agttacaaaa accaacgtcg ggtctacttc taatgtaaca
   103201 tttgaagtat tggacaattg taaaatcatt tttacaacca aatctttaat actgccatct
   103261 tcagcacgtg gcttatacgt ctctggatac ttacctatag ctattatatt attctcatta
   103321 tccagaacag cagcttctct tatcataaat ccaccaactg ttcctggtaa aatagtctct
   103381 ataactatcc aattaggatt tttttcatca attcttagag aatttatatt tccttcccaa
   103441 actacattct ttaaagcagt ttgttcctct gttggctcat aatattctcc attactatct
   103501 ccaacttgaa acttggttaa tccaacaagc tctcctagtg cagttgcatt tgctattttt
   103561 tctctaccaa ttttggttaa tattatataa aatttttctt ccaattatac cacctccgat
   103621 ttaggataaa ctactacatt ttctacacct gtatcatttg caatagctat attaatctta
   103681 caattatttt caatgcattt aatgcttaaa ggataaacct ttatttcttc tctacttatc
   103741 attccagctc cacagtttac aacagcacta cattttataa ttggttcaaa gtatggatga
   103801 acttttacct cttcactaca taccatacct ccaccacaat agaccatact tttatctagt
   103861 attattggtt ctaaatagtg taataagtga gcaggtttta ctctttcaat catatcgcta
   103921 caatctaaaa gagttttata gtcacagtta tttgctataa aactcaatac gaatgtaaat
   103981 tcatcactat aaacttttat atctgtttct gattttgtat atgcctcaca tatacttttt
   104041 ataacttcaa tagtactagt acctctgctt ctcattttag cttttatatt gctacgtctt
   104101 gtgtcaaaat caagttcttt tttttcaatg cagagtatgt cttcccacat atctaatccc
   104161 catgttgcag tgtcaacaaa taattggtta aaggtatcat caatatcttc tttaagaata
   104221 tttaattctg tatcgtatgc accttgtatc tcctctacaa tgtaatttct atcaaatgat
   104281 ggtagtttat caattagctt cattgatttt ccacctcact aaaattaaca gttgttacac
   104341 taggtatttt atcttcatta atagttatat tatctgtact tccatttata agtaggttac
   104401 ttaaatcgtg tacaccagta gtatttataa gtattcccat tacttttgta tagattatct
   104461 ctcctctaat atctctaaag tatgtattta tactttctag gaaagattct tttacattgt
   104521 ctaatgtata tccatcttct agtttcatta ctgcacttat acttatttct attggtaatg
   104581 gtgtcacaac tgttatagtt ggtccaatag gcttctcttc atctatatgt tgctgacacc
   104641 tttcaattgt ttctgtatca acagcttgat tatttttccc aaatatcaag accttaactg
   104701 ttcccggacc atcccatctt ggataaacct taacattata gactccatct acttccaaag
   104761 cccattcttc atagtgagct ttatttccac ttgtagcttg atttctttgg attttataaa
   104821 atctttcttt tagttcttca tctgtctcta tatctgtacc accttcaaaa cttcttgtgt
   104881 tagtaatctt tgttactcca gatatattat caactagttt aaattcacaa tttgtaggta
   104941 aattatattt cttaccaact tccagagctt gaactgggct attgtcacct tcttcactac
   105001 caatagttac atcttttatt actacaaata gtaaatctct atatgatatt attgtgccat
   105061 tatttattac agtacctttc tctccaataa attcaacttc tccatttgac tctgtaccta
   105121 actttctata tacaccaaat tcattgactc ttttatcaag aaactggtta tatgtgtctt
   105181 gtataaaagc cattttatgc atctttgaaa gttctagata tatcttcgaa agttctagat
   105241 tatttccaga taccatgttg tttagaaaag aaccttctcc tttataaata tcaagattaa
   105301 tattttcaag agttctattt tttattactt catatgtctg gtcactatac atttatttcc
   105361 acctccccat agatagtgga tacttttaca tttgcactca atatgtctct gttaaagtta
   105421 gcacttttta cgtttacttc taatatatat ggatttatta gaagggcctc ttttatgaat
   105481 ctactagctt cactttctgt aagacctttt gtatattttt gtcctattag ttctgaaagc
   105541 tctgtcccat attctaaaga gtatatctca tgttcatatc tatttgtctt tatacacttg
   105601 tatatccaaa cttttaaggc ttcttttttt tcaattattt taaagtcacc tttttctaaa
   105661 ataggttcat ctttttcaaa atcccatgcc acttcacgaa agattggcaa ttcttctgtt
   105721 ttaggtaaga tataatcctc tgggacacct ataaaaggaa atattgtact cattataagc
   105781 tcaccaactt acttacaaca gcaaattttt cgcctattct aaacattatt accatatccc
   105841 cagattcaaa gttatctata aaaggatttt ttacttcatg ctggtgttct tgatttgttt
   105901 ctgtgtcaaa tgtttctagc tgtctatcaa tcatccaact atctatcaaa atatcttctt
   105961 tttctaatat gatgttattt gtctctattt ttaaatctgg taatttactt ttaatttttc
   106021 caataaaaaa agaaggttga ttatgatact ttccttcttc tcttattatt cctataaatt
   106081 catttattgg attagccatt atatcaccat ccttttataa tactctccta gctgtgttaa
   106141 aatctcttct actacttaac ttacttattt taactacatc acctttttgt ggagcatgta
   106201 aaaattatcc attacctata tataatccaa catggctgac tggattatga aaaaatacta
   106261 aatctcctgc ttgaagattt ttttgttcta ctttcttgcc ttttttagat tgttgatttg
   106321 acgttcttgg caaactaaca ttaacttttt taaaacaata gaccattaaa ccagaacagt
   106381 caaaactact tggtccattt ccaccccatt tataaggttt acctagatgt ttttttgctt
   106441 ctgatattac tattttagct ttatcagata cattaccaga ataaccacca ataataattt
   106501 ttccttttct tcttccaaat ttactagctt cttcaacatt tccaaataaa atatctatat
   106561 ggtatgttcc attcttttct atagttattg caggtcctac gtcatttact ttatagactc
   106621 catcacgacc agaaactcct gtaattacct gtatttcatc tccatagttt aataaaggat
   106681 gtttatttaa aaactctttt gtataataag tttgctcata tttaccaacc ataggagcag
   106741 cgcaagtttt tttagatggg tcaagttttt tctttctaca atctgtatct ccaccttctt
   106801 cttttctagg acagtaagct gtaaattctg ctgtaaactc ttttcctcct gcataatctt
   106861 ctccccctaa attactttct tccttaggtt catcctgtcc tgctgacttt tcatccataa
   106921 gattttgaaa attaagttca agctcaattt gatattctcc attttgccaa gtatgtttgt
   106981 ctgtatctat ataaaatagt cctacaagct ttgtataaga atctttaact tttactcctc
   107041 taccagttat acaacttaca tctccataac ctttaagaga acagcttttt tctatcccat
   107101 taaactcgct atcaatatct acatcttgat tttcttgttg ctgaattact ttttgcatta
   107161 ttacatttac ttccttaaaa atttcattat ctattttttc gctaatcttg cttccatact
   107221 ggtctaccac tattacttta ttttttacat tttccatgct ctccgaaaag gtggtattta
   107281 taatattaaa tccctcttca aacataacac ttaatgtaac agttcctttt tcaataacat
   107341 taaacttatc taaattggcc tctatcatat actttttctt tgtcttttta cttgcttctg
   107401 tatatgcact cattattgtg tcataaccat ttactcctat aaacatcttt gtatacttga
   107461 cattggtctt tgctattgtt ccaactgaaa gcctattttc agcaaatact tgctttgcta
   107521 tgtcttcaac taacttatct ttaaaattgt atgacacttc actttgtgta agtaaaaatc
   107581 ccatatcttt agatacaaaa ctaatttcat tactgcttga atctttagac ctattaatta
   107641 tcattcctct aaagagttct ttctcatcta catagaaaca gactgtacta gctattggta
   107701 tatcgatttg ttggaaattt acatcaaatg atgattgtat tattgaaaac tctagtgtcc
   107761 ttgatggaga tttataatca cctgaccatg ataccttgtc tactatgtca gttatgtcat
   107821 atatacttcc gttttttatg tgtacccaaa tcttaataat aaaaaatcac ctgccttttc
   107881 atttaattct atcagcagtt atttataact tattatctat aatagttatt gttttggagt
   107941 tacttttggt atctttattc ttttatactc ttttaaatct aatgtaaaat atacatctcg
   108001 agtcccatct ctttcttcat aactaaaccc ttcaattatg acttccatat ttatatttgt
   108061 ttccgtaatt gtaaatctta atataaaacc ttccttcatc catttttcta tcttatttac
   108121 acaatcatat ggtgatggaa aacctgtata gtcacagaaa gtatagtctt tatttggaaa
   108181 aaaacttgat attgaaatgc ttttaagagc tacaccacca aaagttgcta tttcacctat
   108241 tttgagtata ctagaagagt ttacagcagc ttttccatta atactaaagg aagatggaaa
   108301 tactggaaat ctaaatctat cttcagcttg tctaagccac atttccatta taagacaccc
   108361 cctaactgtg ccaattggat acttgcaact aattttgatg ttatcttttc tatatcagct
   108421 tcttctctaa tcactattgt atcagctaac ttagctatgt ttatatttcc accatttttt
   108481 ctgcttctat attgatttgc ttcttgttta gttaaaacca tttcaccttc atggagtctg
   108541 gtttgatagt cattataagg aacatagttc aatccaaatg cattattacc tttcttacct
   108601 gaataagctt taccagaatc accagccttt gttccagcat atggattatc tttgtaattt
   108661 tttttactct tttccactag atttaaaact gttcctgtga tgcttccatt ttttatctta
   108721 ttaatcatag tttgccacca cttgcatata tctttaacta ttttacatac tttatctaat
   108781 atgttaaaaa aagctcccaa tattggctct ataattttcc atccagtttc caacagaggt
   108841 cctaaggtct cccatacagt tttccaaata acacccagtg tctctataaa attgtttatt
   108901 tgaggtgcat attcacctaa aaaagtaaaa attcttgtga taataggact aacagcttca
   108961 actacaggtc cgattagttg gaatgctgta gttactattg taccaaatat acttattaat
   109021 ccttgtgcaa ttggtgattt attgtttata ctatctagta aattatttac taagtttact
   109081 actggaagta atgaatctat taatgctgta aaatcgatat tttgtaatag tgtacttcct
   109141 gcgttaacaa ttgcttttgg tgcattccct atcattgttg ctgcatgatt ttcaaaacgt
   109201 tcttgcttat tttcaaccat cattttacgc ttttcagcct cattagaaat tcgatattga
   109261 gtagaatcag aaaactcttt tccatttttt acacttctag attgcatctg gtcatatttg
   109321 ttgccaataa ttatcttacc attcattaca ttgcctattt taccagccat tttttcagat
   109381 aagccagcta aattgcctaa tccactttct ataaaagttt ttattttctt tagtccttga
   109441 cctaaaatat catcaaaagg tttaacaata ctcttcaagc cattgttaat gcttgtttga
   109501 gctcctgata ttatacctgg tattgtatta ctcatttctt tagctaaccc catctgcttt
   109561 acacttatgc cttccaatgc ttcatcaaaa gttttataat tttctcctac cagagtatta
   109621 agagattcca tgtttccttt tgctgcactt aagaaagctg ctgatacatc ttgttcacta
   109681 cttgtattca tatttaaagc tctaacatct accatagctt gagttatatc tttttctttt
   109741 ttgccaccag taatattact aatcatttta gctttagttc ccattgcaac aacatcttca
   109801 gggtcaaaag gcgtatcatt tgccattctt actaaactgc cataataatc atcaacatct
   109861 atttgattaa cttttccagt atttcttttc attacacttt ctagaacaac tttctgattt
   109921 tgttcctgac caagtaaatc aacacccttt ttcacagcga cacctatagt agcaccattt
   109981 gtcaaatcag atatcttccc ttttatcgaa ccaagtattc cacttgccat atcctttaca
   110041 gctattgcac cactccatac cttacctgca aataatctca atttgggaaa tactttactt
   110101 ataatgccac ttgccatatc ttttatagct attacaccac tccaaaaagt atttttaaac
   110161 aacattaact taggcaaaat tctacccata gcactactca ccatatcttt aagattaata
   110221 cttccttgat aaggacgttt ctctacttgt tttaattttc ccaagatact acttatcact
   110281 ctcttagtca tatcttttgc ttttattacg atattccaaa tcttgccacc aatctttttt
   110341 aaatttccaa gtaatttatt tttagttttt tctacttcat cacttttagc tttaaatatt
   110401 aatataatca taatatttga attaaactca tttttctttt gaatcaactt attaaaataa
   110461 tcaataatca tagctatagt tattgctagt ctcataatac ttccatttaa acttccaata
   110521 actcctgaaa cagcatttat gctagaactt aattttgtca tagttgaact tacactacta
   110581 gcagtagttt gaacttttct taacgaggaa tttaaactgt ttactctatt acttgcactt
   110641 ccaatagaat tttttatgct actagccatt acattagtgg aaagtgaaac agccacagtt
   110701 gctctcctaa aattatcagt tactgatata atttgattca tttttggtgt gtaattatct
   110761 gtaaggtaca tatttatacc ttcttctctc acatttccca ttacatacca cctcctgtca
   110821 aaggacacac tccatatcca tgtttcattt tttcaacttc ttcctcaatt tctaaggcga
   110881 aaaaagcttc aataagcttt aattcgcctt tatccattgc ataaaaaagg gacggtctta
   110941 tacctttttt cttccaataa tagtacatta ttgtagtcct ggtatccgtc cctattagtt
   111001 ttttacctct tctatcactg catttttacc ataacccata acatcttgaa gtattctata
   111061 taagttggta atttcacctg gtaataacaa ttttcttgct aattcttttg gtgttggagc
   111121 cttaaattta tccattagct ccttattttt aaataaaagc tttccatcca aatcacaaac
   111181 accttctata attgtaagca tctgcatctc cggtaagtct atatccgttt tcatattttc
   111241 atcaatttta agacaagtat tttgtatctc ttcatcttta cttattgtta aagctctaca
   111301 cattacttta aattcctgcc caaatatagt tgataatctc ttaagttcaa ctatagtact
   111361 tggtctttct aagttttctg tatctgcatt taaaagtaaa tctactatgt ttatattttt
   111421 taataatcca ttttcactca ttattatttg ctcctttatc aatcaaattc aatcaactaa
   111481 cttttttact tattaactat ctgaatttat taagtatata tttactaaat atcagtataa
   111541 aaccaaatat aaaactaaat ataaaactaa attatatcaa gaaaatcata ctcagtaaat
   111601 gtgaaaggtg cttctatctc tccttttacg ccaacctccc aatcagctaa agttaaatca
   111661 tcaaatgcta tattctttac tgctattctt tctgctccat aagaatctgg gtcatttaat
   111721 ttagatatag caacaaatct aggttcagaa cctctcttta tcttttctcc aattaacttg
   111781 tgcattcttg aactaacatg gtatagagtt attgagcctt ttcctttata tcccatatac
   111841 tttgtatcag tacccatttg acctgctatt ataatatctt cttttgtaaa ttccatcttt
   111901 gcttgaaact tctttacttc tgctactttg tttccatcaa gccaaagttc tccccaagta
   111961 ccactcatta catttctagc ttccatattt gccatattaa taatcctcct atatttctat
   112021 tgataaatct atatcttcca tagcatcaag tacttttatt tttgctttta aaaatacttt
   112081 agaacctgtg ttagcttctt ttatttcttg taatgtcata taagataaat ctactccttt
   112141 tgattttaaa tacgattttt gtgcttcaaa atctatttca acagtagaat cagattctat
   112201 aagtgctgat ttttctaatt cttctaaata actttttata gctactatca ataaacattt
   112261 gttgtcataa ctgttagtaa cctttcctat atagtcatct attatcacct ttcttatgtc
   112321 actatgtata atatctaaag tgtcaactat ttttattttc tggaacattt ctcctttttc
   112381 tgctgttaat tcagttaaag aatttactcc tctagcaatt cttatagctc ctgcttcttt
   112441 aataagtata agctctcctt tattaacctt tgattctgca tcaactttcg tcatcttagg
   112501 tatatcgact acatcactaa gtttagtata agttactgat tgacttaaag gtgtacctgc
   112561 tataagtcca gccaccctac ttgtaaactc atcaacactg tatttctttt ctccaactaa
   112621 cacatcttct gtagtaaaat taattatccc ttcatgattt cctacaactt ttcctaatac
   112681 agctttaacc ttaaccttat ctatatctct aagtttaatt atccaatttt ttatagcagt
   112741 cttatcagct tctactgctt ttggcataca tagataatta aattccttag tctctaaaaa
   112801 atctaatgca gtttgaatat ctgcttctcc ttctattaca taaactaata atttatttgg
   112861 agtgttaaca tttcccatca aggctaaatt tatatattct ttattttcag cagataaatc
   112921 aactggtata tcctcttttt catgtatttc attaagacct agtgccttag catctttaag
   112981 caccattgca attattcctc tagctgaacg ttctttaaca gttgtagcta gctccttaaa
   113041 tgatatgttg atacttggta atcctatagc catactatca ctctcctaaa tttaaattga
   113101 tttcttccat attttcatat actacatctt cttcatatac actatccaga tagtttagtg
   113161 taagtgtaaa gttcaataca taaattgact cttctttttt aatactttgt tctagctttg
   113221 ttatatttaa ttttctgtct gttaccttta tatttctgtt aaatagctta tttaattcat
   113281 ctgaaacttc atacattcta atactctttg actgtggttt tggtaagtat tttatagaga
   113341 taacaatatc tttgttattc gtatttaaca ttacaggtgt acaaataact gatagtatac
   113401 ttacaaaaaa acaagaccct tcagagcctt gcacactttc atcatcaata aaaatacttt
   113461 cagtaaagtt ttttttgaga atctcaataa ttgtttctaa tatttccttg tatttaagca
   113521 aataatcacc acgctatcac taaatattct tgcttaatct gataatctta ctataaatga
   113581 tataagtcat ttttaaatat atatctcatt tattcctgtc aagtatcttc tatattttta
   113641 ggtaatatta ttcttttcaa tctatcacct ccttcaatat ggatttcttt cacaataaca
   113701 ttatctcaca tattttattg cctattgttg caatggtgta tataaagtgt tgtaaaattg
   113761 tcctattttt tataatatct cactcaattt aaatatcatc tttttcttta aattgtagca
   113821 agatgttcta tctaagtgta gtttcataga aatatatgtc atattgtttt ttgtcttact
   113881 attataaaaa agattaaaaa attccatttc tatatcattt agacacgtta gagcattttc
   113941 tatcttctct ttttctattt ctatatcttc tttttccatt tttaattttc ttaatctttc
   114001 ctctcttttt aacacctcat tttccacaga agagcttatg ttatatgtgt tactagtctt
   114061 ttctgtatat accattgctc cacatccaga gtattcattc tcacatcttt ttatgtccaa
   114121 gttaatattc tttatcttta tatccaaata cttataatta tgtaatcttt tatctgtttc
   114181 tttaaataat atatcttttt tgttttccat agtacttctc cttttttata tacttattat
   114241 tagcttcaaa tttacaataa tctctttagt gcacagtttt ttactaatct cacaactttc
   114301 aagaacatat tgttctatga ctgtataaaa aaaacttctt ctatattttg ttctaaaata
   114361 ctagaaatct tcttagccat aagaagtcca ggatttttta tgcctctttc tatttgagat
   114421 atataatcat ttgtaattcc agcctttctg gcaagttgaa tttgtgtcat acctttgcat
   114481 tttctataat atttcaagtt atttttaaac attgttttat acctccatta ctattaagaa
   114541 tattttgttc ttcctcactt agattatata gaattatttg ttctttatca atatatttta
   114601 gaaaaaaata ttcttttata ttttattagt tttatttttt agaacaattt gttataatct
   114661 atacataagg tggtgttata atgtttgcca aaagattaag agaacttaga aaggaatttg
   114721 gattgactca aagagaactt ggagaaaaag taggcgtttc ccaaagagtc ttagggtact
   114781 atgaaacaga aaacagattt cctgatgaac acattttaaa taaattggct gatgtattta
   114841 atgtatcagt tgattacctt cttggaagaa ccttagttaa ggaaaatatt gatacagtag
   114901 ttgcacatag aaaaaatcca catgaagagt tacctgaaga agcacaagaa caacttaatg
   114961 attatataga atttttacta aataaatata aaaaaaaata aaccatatga tgagcagtct
   115021 atttttctgc tcttttaata taatttaaag gcaaacatac attctatttt agggggattt
   115081 ttatgaataa tttggataag ctttttgaat tagcttctca agaagggata ataattcatt
   115141 ataccactta tattgcaggt gatttagaag gactatatat aaacaaacat ggtattaaaa
   115201 ttatatcatt actcagtaat ttaaaacaaa actcaaaaaa attaacatcc atcttagctg
   115261 aagaacttgg acatcatttc actagccttg gatactatgt atcctcttat aacgattatt
   115321 atacaaaaat tattatagat aagtgcgaaa ataaagcctt aaaatgggct tgtgagttct
   115381 taattactga agaagatata ataaacataa ttaactctgg catcacctgc gtttatgaaa
   115441 tggcagacat acttaatgtg gatattactt tctttcaaaa aagattagaa tttttatcat
   115501 taaaaaaaca gtctttacaa cttggaaata ataaatattt aatattaact aatttgccgt
   115561 atttctacat atttgatcca atttcataat aaaaatagta gtaattttaa ctggcttaac
   115621 agtaaaatct atatatttat tttaacaaat tttggtttct ataaattcaa tattaatata
   115681 taataatgat atcatattat ttaaaattct aaaaacaaat atatgctttt gttaagaaag
   115741 gttgtttgat gaatgtataa agaaaagttg tttgataatt attttaagtt cttagcacta
   115801 ttattttggc caattatgtg gtataagtgg atagtaattt caaatggtac tcttgaaaat
   115861 atgttattta ccatatatgc aatcgtcgca attgttttca tcattttata ttcggtgttt
   115921 atgataaaat ataaagacat tacacaaata gatttctttt acaggataag tactctactt
   115981 gcttttatat ttacactttt tagcttttta atatacccaa agagtttatt tttcttgtat
   116041 ttaaagatta tttttactgg aatatacctt tattattcaa tagtaaaaac tcttaaattt
   116101 aaagatgacg aaggtgtagt gggtattatg agctcacttt tattaattgt aataactttg
   116161 ttctactaaa tttaattcta tttgacttaa tatggcttta aatattagac atctacatta
   116221 ttttctgata ttatttaaga tggtagtctt atattaataa tgaaatacac tatgaaggag
   116281 ttaactatta tggaaaaaaa agttttagca acagttggag aaaaagagat aactaatatt
   116341 gatattgaaa atgcattaaa atcattagac ccttatcaag ctatgcaatt taaaactgaa
   116401 gaaggaaaaa aacacttatt aaatgattta gtgaatcaag aattattctt cttagatgct
   116461 aaagaagaaa aattagatga agaagaaata tttaaattag aaatgaaaaa gatagaagaa
   116521 aatgtattaa agcaatttgc tataaataaa gttttatcta gtgttaatgt aacagaagat
   116581 gaaaaagtaa aattctttga agctaataag agctctttct ctaaaccaga aagtgcaact
   116641 gctaaacata tattagtaga tagtgatgaa aaagctaaag aaatacttgc tcaaataaaa
   116701 tcagaagaaa tatcttttga agatgcagct cttaaacatt cttcttgccc atctaaagat
   116761 atgggtggtg atttaggaac attcggtaga ggacaaatgg ttcctgaatt tgaagaagct
   116821 gtgttctcta tggctaaagg tgaagtaagt gaaccagtta aaactcaatt tggataccat
   116881 ataataaaat tagaagacct tcaagaaagt acagagtcta catttgatga agttaaggct
   116941 gaagttgaaa aaagtttatt atatcaaaaa caaaatgaag tttatggaaa taagataaat
   117001 gctcttaatg ctaagtacgg aaaccttgta aaatacaacg attaatcata aggtcatata
   117061 taaaaaagct gtcttttcac aatatttatt agaaaagaca gctttttata ttaaagttta
   117121 aatattcagt ttcatattat cattctttta ttgtaaagaa ctcagcttaa aagtttaaat
   117181 aagattttta attatcatta gctaaatttt tatatccacg tattatctca taacagtaac
   117241 ctattacatc tcttcttttt attatcccaa taaatgtgtc ttggtcatct ataacaggaa
   117301 tgaaattttg atttaaagat tttataacta aatcttcaat atctgcgttg atggaaacag
   117361 gagaattatc catttttcta tttatatctg tcactggaac atcttccaat ccctttaagt
   117421 ccagatttaa atcatttttt aatgtccata aaaaatcacc ttctgttata gttccaacat
   117481 atttaccatc cttacttatt attggaattg cagagtattt gtgatattcc attttttcta
   117541 gggcttgcct tatagtgtag tcttcatata tatatgctac ttcacttttt ggtgttagaa
   117601 agaataatat gttcattaca ctacccaccg ttactgaaaa cttataaata ttactcaata
   117661 tttataatgt tacttttttg cagtaacttt ctcctttctt attttctaag tattcttaat
   117721 actatacgct gtaacaagcg tttttccttt gctcatttta atcttattat gctttattaa
   117781 tatttttata tggtctatca gtatcactta ttctcttttt agaaaattta ctaaaaatta
   117841 attgacttaa acttagccat aataatttta ctctacacta ttaattttaa catatttatc
   117901 tcattattaa tgattttatt ttaataattt taatttattt tgctattaat tttatttaca
   117961 aaaactgaaa aaaccgctaa atgattagcg gcttatctct catattacta gaacactaat
   118021 atatatgaat ttttaattat aatctaacta cgttagcagc ttgaggacct ttagctccat
   118081 ctactacttc gaactcaacg ctttgtcctt cttctaatgt tttgtatcca tctccagtta
   118141 tagctgagaa atgtacgaaa acatctcctt caccttctac agatatgaat ccaaatcctt
   118201 tttcgttgtt aaaccattta actacaccag ttttcattaa taaatcctcc taaaaaaaca
   118261 caaatattta gctactcttt tctgtaacct tattactact ctatcatata tagctatgtt
   118321 tgtcaattat tattattttt atacattaat aatcaatttt tttactttat aattttaaat
   118381 gattattatc ttttacactt tatttttctt tataattttt taataattta tttttattat
   118441 atggaatctt atggacttat cactccagcc taaatcccat ggcaccaaca ttctatcagt
   118501 attatggcaa gttaccaaag gataccctct tgagtctaat cctgtcactg tcgaaacatg
   118561 tgttattctg cctttcttct cataaccaac aaaatcccct ggacgtaaat tataagcttc
   118621 tttgtatact tcttcatagg aacctttagc aattaatgaa cctcttccac tatacagtgc
   118681 ataattttta aaagcttgtg catttaccca tgcttttgta cctgctctct cgctataatt
   118741 ccaaattgag ttctttttga accttccact ttcaaacatt atctgtgatg caaagtttgc
   118801 acaatctcca ccttctggat tataatccct atagtttgga ttaaatttca taccatgttc
   118861 ttcatcagct gcggctccac agtatttatg tgcataatct atagcctttt tttgttcatc
   118921 tgtaagctgt aactctacac catcttgttg accaatatag tttcttatat catcagattt
   118981 tatattttct aaatttaaag agtctgcaaa agggtctgta taccactctt tagttatgac
   119041 atattgatta tctataattt ttacatttag ataatgatat gtacctattc taaaggcatt
   119101 ttctttgtcc ttttgatttt catatgaata cttatattca gtcgatactg aacagattat
   119161 accatagagg tctttttctt tttcttttat ttttttaatc ttaacccttg tctttatgtc
   119221 tttaaatttt acaccttgct tactagacca gttttctaaa tacttcatct tttttacttc
   119281 attttcataa gcccacagac caaatttttt atccgtctca taaagacctt ttaaaatgtt
   119341 ttcatttttc tctaatattg ccttatttct gtagtcaaat aagttttcaa gcaatagttt
   119401 atattggtct tttacatcat caccttcaac atttgcagat tccatgactt tttcttccat
   119461 atttttcata cttaaatcat tgattaaaaa tacacctgct gtagtagcta aagacaaaaa
   119521 tacaaatgcc attatacctt tgatgtactt attcttattt ttcagtattt tcaaagctac
   119581 acctcccaaa tagtacacct tacaaatcaa attacaaaga atattctgtc acatatagta
   119641 attttcatat ttaataattc tctattttat tatgtccaat attaaaaatt aattgtatca
   119701 atacactgtt ttttttacaa ttttttattt tataatctac ttttttcttt tttttatagt
   119761 aatatatatg tatataaata ttttggtatc attataatta atacatacta atggagggtt
   119821 ttttatgcaa aaaaaagtcg cagcaattaa tgacttatct ggaataggaa aatgctcatt
   119881 atcggttgct atacctatac tttcagcatt aaaggttcaa tgttgtccat ttccaacggc
   119941 catactttca agtcaaactg gttatcctga atttactttc ttagacttta ctgatgaaat
   120001 ggtaaaatat tcaaatgttt ggaaaaattt aaaagtcaat tttgatagta tatatagtgg
   120061 ttttttgggt tcaaagcatc aaattgagat agtggctaat tttataaacg attatcccaa
   120121 tgcttttatc gtagttgacc ctgtgatggg tgataatgga gttatgtatc caatattcac
   120181 agaagaaatg agacaggaaa ttaaagaatt agttaaacat tcagatttaa ctactcctaa
   120241 cttaacagag gcttgtttct tgactggaaa tgattatact aaaagcgatt ataatagaga
   120301 tgagcttata tatattgcaa aatctgtatc tgatttggga cctagcaaag tcgtgattac
   120361 tggtatatta gaagatgata atatattaaa tttggcttac gatagagata atgaccatgt
   120421 attctttaca tcagtcaaat ataataattg ttcttacagt ggaactggag atatattcac
   120481 atctatactt tgtggtatgt tagtaaataa acatgatttg ggagtagcgg ttaatactgc
   120541 aacagatttt atatataaaa ctataaatta cacatctcaa tttgatactg atagaaatga
   120601 tggagttatg tttgaaaact ttttatcaga tttaactaat atataaagtc aaaaaaacta
   120661 tccattttat aaatacctat aaatcataaa atttaggtat ttacaaaatg gatattattt
   120721 actaaactat tggtatttca attgttacca tagcaccacc agttttcaca gaattttcaa
   120781 tatataaaat cccattatgt ttttgtacaa tattatttac aatatagagt cccattccat
   120841 aatgagattt agaatttcta ctcaaatctc ctgtataaaa ctgttctgta gcttttgaca
   120901 aatctgcttt agaaaaacca cttccacaat ctgtaactac aaattttaag tatttattac
   120961 atactgatac acttatgtat agtttactct ggcttggtga ataatctata gcatttgaaa
   121021 ttatattcat aatagctctg aataacagtt ctctatctat agttatattt ttaggcaaat
   121081 tatcttgttt ataaaactcc acatctaagt ttttagtact agctaatgct tctatttgca
   121141 ctaagacatc ttttataaac tcactcatac tgattgcttc tttatttaat atatagccat
   121201 tctctgtttt tgatatatct attaaagtat taatatattt ttctatttga gtgacaccct
   121261 ttgagatata ttccatgtat tctaataact caggattttc atttatttca attaataagt
   121321 cagtatttcc atgtataatt gttagtggtg tttttatatc atgtgccagt gcagatatct
   121381 gttcctttct attttcttct agcatccatt gtttttctaa agaatctttt aacgccaact
   121441 tcattttatc catagaaaaa aggacattat taatttcata aattttacta gattctacaa
   121501 caaaatctaa atcctgttgt tctatttttt ctgtagtatt ttttaaaagc tccatttcaa
   121561 tattaaattt cttgccaaat acttttgata atataacaat ttcaataaaa aatattatac
   121621 taaaaataat catacccaat gtctctggtt ttggtaaata tgctcttaaa attggagaac
   121681 tatactctga tactattttg tattttatta taaaaacttc atctttctta aaaaacttta
   121741 tataactttc tgaatatgca tgcctttctt caatatctct cattaaattc catacttctt
   121801 ttgattcttt tttattaaag gtacctgaaa ttaaattccc atctaaagta taaaccccat
   121861 actcatatat acttggaatt atatcttcag ttactttttc acttgaaata atctgttctt
   121921 tatatttatt aaattgtttt tctgcataat tagctggtaa aattacacct gatgataata
   121981 atacagaaaa tgataacatt aaaaagagta caattgaaat tgtcataata aagaataaag
   122041 ataaatattt tataaaaata gttcttaact tttcaacttt tttgttgtta gattttttac
   122101 ctccaagcat ttgtaccctg tcctccaata gtttaattaa ttcataatta atacccaacc
   122161 agttttttat ttgattattt tatatctttt tattgctaag ttatatttta acataataat
   122221 ataaataaac agtcaatttt tactctattc ttctgatttt ttaccttccc atttagaaaa
   122281 ccaaatacat aaaattacaa atgctaaaat tgttacaaaa ccacaaatta aacctgttga
   122341 ttgatatgat tttattgatt caacctttat atattcaacc gttttagaac ttgaaaaaga
   122401 cgaccaaata gttataaatc taacacccca tgcacaagga aaatactgcc aaataccaga
   122461 acccaatcca gttaataata atgctgaaag taacatttca actataccta ctccaattga
   122521 tgttcctttt ccgaacctta aacttaagaa taaatgtaat atgtattcaa ataaattaca
   122581 cgcaattaaa attagaattg aaatcatata aaagcttgat gtaaagtaag ccttagatat
   122641 accaaattta aaacctaata cagacactaa tgttgctaca aaaccaagac atactaagat
   122701 tatatattta cttataagag taagatattt tggattagat gttgttaaca tatgtttata
   122761 attccctgca taatattctt gttcaacaaa cattgaacac acaacacttg acaataaagg
   122821 aaaagctatt gctataactt gtaaatatgc tactatcttt agtatattat cagctcctga
   122881 aaccttataa taccataaaa acaatcccat ccccattaaa gcaatgcaaa tgtgcattag
   122941 tattataaaa tttctcttta attttattaa atcagaacaa aatattctta ttaactgtct
   123001 catattactt cacctctcta ttattgaacc aaacccttgt agctaaagca aataatacaa
   123061 ataaaacaat agatattaat actcctggca aaataacagc attatttaaa aattcacttc
   123121 cctctggtac aggaagacca tttggcagaa tatgcaatac aacagccatt aatcttgaag
   123181 gaatcgaata tggaaacata taccacattt ctgtagttga gaaaacagca actccaacaa
   123241 tagtaaagaa catatttatt agaactgtaa caaaaatacc aaattttgaa gctaaaaaca
   123301 tacaaagagg aatctgccac ataaatagta aaataattaa tatagttgca atgatatttt
   123361 gacctattga aatagtttct ttatagatta tcccaacaaa aactacacct attgcagaaa
   123421 taattgatgc tataaaacag caaataatac agtaaatcat ttttccagtc caaacatctt
   123481 tcatttcaat tggcaatggt aaaataccac gatatttact tttttcatct tttaatacta
   123541 ttaaagaaca tattaatgtt aatgctcctg gaagaaatgt cgtataccac cagttaaaag
   123601 cagcattttg ccctccacct agtccacaca aaagtataca aaacactgga actatccata
   123661 tcaacttcat tccaaaagtt cctttcatct tttgaaattc cactctaata aatctttcca
   123721 tattactccc ctctctttct attttcagct acaactttca taaaaagttc ttctaagttt
   123781 tgttcttttg atacttctcc ttgataaccc attactccat tagaaattat tcctatttca
   123841 tctacaactt gttcaacttc agacaagata tggcttgata aaataactgt aattccttgt
   123901 tttggaaaag aacgaatcaa ttctctaagt tcttcaatac caatagggtc aagaccattt
   123961 gtaggctcat ctaagattaa aagttttggg tgatttaata atgcaatagc aataccaagg
   124021 cgttgcttca tgcctagaga gaattgacct gaacgctttt taaaggtatc tcttaaatct
   124081 acagtctcta aaacttcttc aatgcgagag tcaggaagac caagtaaagt agtatgaact
   124141 tttaaatttt ctcgtgctgt taaattctca tatatagcag gagactcaat aagagaacca
   124201 atatttgata aatcctttct agtccatcta tgtccctcaa acattatttt tcctgaagtt
   124261 ggatttaaaa tcccagttat catttttaat aaagtagatt tcccagctcc atttggtcct
   124321 aataatccat atatagaatt agatttaatt gctagtgaaa tgttatcaac tgccatctgc
   124381 tccttaaatt ttttagaaac tccttttacc tgcaaaatat aattactcat aattttcatc
   124441 ctttcttttg tcaaacttat ttacaagaat cattctaaat cataaatata aggattttat
   124501 aagaattaaa aaacaaaaaa agatgtgtta aaaacacatc tttttttatc ttaattctat
   124561 taattttcca ttgtagtata tctctacttc ttcaatccaa atgctattat cttcttcttg
   124621 gatgacattt ttaataatat tatttatagt atatattata ttttgttcat tcaaataatc
   124681 atctttccaa gaaactctac tttttttatc tggttctatc aagtttattt taacaagatt
   124741 atctttttcc ttaacttcta cttccatgtc taaaccatta aaatactcat ttgataatgt
   124801 atctaagatt aatcgcagtt tatccttaag tgaactttct tcatcaatct gtaagtactt
   124861 tactattttc tcatcctttg aaattatctc tataggtatt ttagtagttt ttttagaatt
   124921 aatcatttta ctagttgttt cttcttttgc atcttcatcc ttctttacaa ctgctgattc
   124981 tttagaatca actagctcaa ctgcactgat gctataatcc atacatgccg tactcaataa
   125041 agtagtagca attattaaaa aacttactgc tattttattc ataagtatcc ctctcctaat
   125101 tctctttcga tacttattat accatagtat agattatatt tttatacttt taaatcaatt
   125161 tataaattat tatagtaaat tatttacaat tctaagctat ttgaatttat ttttatagta
   125221 tattctttct ctaaattcga cagattttta ttcaaaagcc cttttatttc cctcgtattt
   125281 ctatacttgt tgctatgttc ttcatcatgt tcatagtcat atgaatcatt gtcatattct
   125341 tcatcattat taaattcttc aattgcttct tttgacttta tatcacaatt aaatttatac
   125401 ttatttactg gtatatcaag tcttacctta gaatttggaa cttctatgtc caggaactta
   125461 gcaattggca tatcagagta caagtaaaat tcactttcat aatttgaatt tctacctatt
   125521 ttctctttta tatttacatt ttcaggtata tactcttcta tattattgat aaatacatct
   125581 tcattctctg aagatatata caatgactct gattctatgt ttacattttt aacgcctaaa
   125641 attgattttg ttgacaagtg aagattgtta ttagatatta agtttaggtt ttctaatcta
   125701 tttactttgt tctctgttat agctctacta aaacctccat aagaagtttt atatgttata
   125761 gtatttgaag ctacattatc gtatacaaat aagtgtgagc ttatacttga tgcatttatg
   125821 tctacattat ttggtacata tattataatt tctctataat catgtgaaaa catactattt
   125881 atagatgtat ttaataattg gtcgaaattt ttaatctttt taattttatt ttcatatttt
   125941 ctttcacctt ttacaactaa agtcttatct tttaaagtta cattgtattt gtaaaactca
   126001 ttatttcctc ttgttgttac acgcacatct tcacttgaac ttttctttat tgtaacgttt
   126061 atattgtcaa cagctatatc taacttgtca atatttactt tttcttgata aagtttattt
   126121 tcttttttaa attcagcttc cttttctaaa ccaaagttta ttaggcttgg cataactaaa
   126181 atccctgacc atgttgtccc tattatacct attaccaata aaaccgcagc aaatatagca
   126241 agttttttat tcatgtttat cttctccttt cttattttct atatcttcaa ggtccttata
   126301 tatcgcctca aaatttatac tatcatcatt atattcatca gtttctttta tgctttcttc
   126361 ttctctattg tagtaatcat tattatatga atcttcatta atgtctttat tcaaatcttc
   126421 atcatttaaa gtagcttttt ttcttttttc catcttttca tttgctttta tataaatatt
   126481 ttttctcttt atccaatgta tataattatt tagtaattgt ttacctagtt ttatggcaaa
   126541 taataaaatt tgccatgcaa gtatctcaag ccctacaaat gctatggttg cgaaaataca
   126601 aaacatcata acatctggaa ccattgctat aaatttaatc acaaatggaa ttaatataac
   126661 aaaagcaatt aatgagcata ctaatgcaat agtagcagat acaatagcac atacaaacgc
   126721 aaatgctgga acaattagaa ataaagataa cactactaat aaccccttta taacttgtct
   126781 ggataatcct cctacacctt cttctatact tggtgtaagt ttatcattta tattttcttt
   126841 tgatttattg tacttttcct tagcttcatc tttcaagata gaataatcct tttttacatt
   126901 tgatttaaat ctactaaatt taccatttaa tatgtctgta ttcattattt ttccatctat
   126961 attttctttt gatttactat acttttcttt tgcttcatct tttaagatag agtaaccttt
   127021 tttcatatct gatttaaatt tactaaactt atcattcaaa acatctgtat ttattatttt
   127081 ttcctcttca atattttttt ctttagtttg taagataagt tcttttgcta tagattttgg
   127141 tgagccaagt gatgctatta tctccatatc actctttccc tctataagac catctacaaa
   127201 atactcttca taatctctca atatatcatt aacttcgctc tcagaaaaat ctttttttag
   127261 ataatccttt aaaatttcaa gaaactcagt tttattcaag ttcattacct ccctcatctt
   127321 cacttattaa aatctcaaca gcctttacaa attctctcca ctcttccatc agattggata
   127381 aattctcttt tcctagtgaa gttattctat agtattttct agcaggacct tcattagatt
   127441 ctagtatata tgtttcgaaa tacaaatctt ttgtaagtct tcttagaata ggatatattg
   127501 ttccttcatt tacatctatt actttagaga tgttatgtac tatctcatat ccatacatat
   127561 ctttcttaga tatgagagca agtacacaaa tttctaaaac accctttcta aattgtgtgt
   127621 tcatatactc catcctttct ttaaatacac agtattgtgt tttacaaggt actatgttaa
   127681 aacttcttat atcctcataa taacacagta ctatgttctg cacaatagtt atttttaaat
   127741 attcttgttg attaaatcct tctataaatg tataatactc taatcagata tattttatga
   127801 aagtggtgat aaattggcta aaatgaaaga tgataaaaca atattaatcc taactgctca
   127861 atttggtgct ggacatataa gtgctgcaaa agcagtcaaa gaatgtatta ttgaaaaata
   127921 tagtaactat aatgttgtta tacaaaactt tataaatgca agtattccca tgatgaataa
   127981 gcctatggta aaactttatg aaaacaatac aaaatatact cctggattat ataattacta
   128041 ttattacttt aagaaatcgt ttgattcaag acatgattta tctcataaat tatatacacc
   128101 taaactttct gagtatattg ctgatataaa tccagatttg attatctcta catttccact
   128161 agctgctgct tgtgtaaata actttaagat aaaaaatcct gatataaata tacctacact
   128221 tacagttata acagatgttg tagatagtat ggaatgggtt tttgaaaata cagatttgta
   128281 ttttgttcct tctcctgaaa taaaaaatag attttttcag aaaggaataa atcctgactc
   128341 cataaaggtt actggagttc ctgttgataa gagatttcaa attgaaagta aagaactatg
   128401 ttgtgataaa tatagactat tacttctagg tggaggaaga ggtctatttg atatagatga
   128461 ggattttatg cattggatag atgaatttat tgaagaacat agtaattcta tagaaattac
   128521 aatagttact ggtaaaaaca aaaaattata tgacaatcta actcataaaa aacctctaaa
   128581 aaatattaaa gtacttggat ttgtaaacga catgtataat ctaataagag aatgtgacct
   128641 aatgctaact aagcctggag gagcaactat atttgaagct attcaatcac aaactccagt
   128701 actcgtaaaa atgccaaaag ttggacaaga aattgaaaac gctaaattta taatagataa
   128761 gggtcttggc atgatttata gtgatgacct agaccttaaa aacatatttt ataaattagt
   128821 atcaaatgaa tttgattcta taataaactt tatgaaaaaa aatttaaaag aatttaaaac
   128881 agtcattcat ccagagaaaa ttgctgatta tatatcagaa ttaatagata atcattacag
   128941 ttaaattgta ctattaaaaa atttcaaaca taaaattaaa ggcaatcaag tatgatttta
   129001 cacttgagaa tttactcata gtgtttaata atacttgatt gcctttatca tatcaaaatc
   129061 aaattgttat attagtatat atttttcttg tactgcatat acagttgttg tatttcttcc
   129121 atacttctct ttaattctat ttgtaaatct gaagcagtct ggtaatcctt attttctata
   129181 gcttctctca ctctagtgaa tagtgattct ctagttaaag tatccttcat aatattgaac
   129241 tttaaatccg atattgagtt ccaaactacc tcatcaagcg catccatatt ttcttttgtg
   129301 tgtatcttga caatacttct tattttttga atcccagcct ctattattct agtttttaat
   129361 ttcttttgcc acttatctat agctccaatc ttaaatgatt ctattatact atcagtaaat
   129421 acatcacctt gttttaaaga ttttaatttt gaagcatata tttctaagtt tttcatattt
   129481 tcataaactg tagctggtgg tattccaaat cttgcatttc tttcttccaa actataatgt
   129541 tcaaatacat cattttcatc tctatatgct ctatcttttt ctaaatagaa actttcttca
   129601 cctacatttt tagataactc tttttcaagt tcttttgtac taagaccact cttagctgct
   129661 gcttttatac catccaacat tgtttgataa catcctgcta ttactaaata cgtgttagat
   129721 agagggcttg gtgaccttaa ttcaaatctt acagtctttg gatttttcat atctcttatt
   129781 aatccaacaa gcactgacct atttcttgat ggaatctcat aactatgccc taaagatgta
   129841 actatacata caggagcttc aaatccagga actaatctat taaatccatc attagaagct
   129901 gttacaattg ggtttaatac ttcataattg taaagaagtc ccataagagc cccatatcct
   129961 agttcactta gataatcttc ttttaaatct tttggagcaa atagattttt tatacttcca
   130021 tcctttaact tcgcacttac tcctacatgt gtatgtccac cacttcctgc tactccatga
   130081 attggttttg ctttaaatgt aacttctagt ccatgtgatg taaatacatc ctctataaca
   130141 tctcttacta ataattcatt gtctgctgct tgtaatggtg tagaaaactt ccaagaaacc
   130201 tctaattgct ccatagcatg gtttgttctt ccatctatac taatagaact ttgtattcct
   130261 ccgacctctt tgtgagccat ttcagggttt acacctagct tttgaagtat aattaaactt
   130321 ttctctaaac aagttcttat aataccatga gttcttttcc agtattgctc ttttaggctt
   130381 tgtgatacat ataatttctc taagtcagct ttatcctcag gagtattaac ccagaactca
   130441 agttctgtag ctgctgttaa cattatttcc tctatatcat ctactgaatc tattcctatg
   130501 ttatttatta catgtggata ttctctaaat atttcataca ttgacttttt aaagtactta
   130561 tctgcttttt gaagtactcc tctagaacat acttttttat tatcatgtat taaaaatgca
   130621 ggtatcttta atgttccaac aggtagacct acttcttcgt ctatatattc catattgtaa
   130681 tctacatacc aatgacaact tttatctggc attaaatcta ctttcgcatt atttaatgta
   130741 gctatattat aaagctcaac acttgaacca tcagtctgta tagctgattc caaaaattta
   130801 tctatatcct ccaaaaataa ttctacagga atcttttcat ctgttgcatt tcctcctaaa
   130861 tcaaccccca ttaaggaaac aaatcttata tttttattgc tttttaggat ttctcttaat
   130921 tcttcattag tgtgtttatc tttctctatt acgtataata gactatccat ttttccactc
   130981 tcccataatt tttatgtata ttttattttg ttaaatacaa gataaatttc attttcctta
   131041 catttatgaa tttttcttgc aaattattcg tgttttattc gtgtttttat ttatattatt
   131101 atatatcaag tataaaaagt tcgcaatatt ttttattgga aaaaatatta tacatacaat
   131161 agtttaacat ttttacaaat atggggtata ctaaaataaa agtattttta tttgaaaatt
   131221 taattt
//
LOCUS       DAEPUT010000003        95903 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.003, whole genome shotgun sequence.
ACCESSION   DAEPUT010000003 DAEPUT010000000
VERSION     DAEPUT010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 95903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 95903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..95903
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.003"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            228..1379
                     /locus_tag="KRL22_000274"
     CDS             228..1379
                     /locus_tag="KRL22_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBH1270799.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVDNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1425..2600
                     /gene="thiI"
                     /locus_tag="KRL22_000275"
     CDS             1425..2600
                     /gene="thiI"
                     /locus_tag="KRL22_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBH1270800.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2776..3579
                     /locus_tag="KRL22_000276"
     CDS             2776..3579
                     /locus_tag="KRL22_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1270801.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKDKNEVIKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDVHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3822..4463
                     /locus_tag="KRL22_000277"
     CDS             3822..4463
                     /locus_tag="KRL22_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBH1270802.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
     gene            5874..7544
                     /locus_tag="KRL22_000278"
     CDS             5874..7544
                     /locus_tag="KRL22_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HBH1270803.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYEEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRINYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQTQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(7666..8400)
                     /gene="pflA"
                     /locus_tag="KRL22_000279"
     CDS             complement(7666..8400)
                     /gene="pflA"
                     /locus_tag="KRL22_000279"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBH1270804.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(8560..10791)
                     /gene="pflB"
                     /locus_tag="KRL22_000280"
     CDS             complement(8560..10791)
                     /gene="pflB"
                     /locus_tag="KRL22_000280"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBH1270805.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            11084..12145
                     /locus_tag="KRL22_000281"
     CDS             11084..12145
                     /locus_tag="KRL22_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBH1270806.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            12236..13849
                     /locus_tag="KRL22_000282"
     CDS             12236..13849
                     /locus_tag="KRL22_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1270807.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            14124..16109
                     /locus_tag="KRL22_000283"
     CDS             14124..16109
                     /locus_tag="KRL22_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH1270808.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKAKSFDEFYKIITKRR"
     gene            16114..16548
                     /locus_tag="KRL22_000284"
     CDS             16114..16548
                     /locus_tag="KRL22_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HBH1270809.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            16577..17137
                     /gene="srlA"
                     /locus_tag="KRL22_000285"
     CDS             16577..17137
                     /gene="srlA"
                     /locus_tag="KRL22_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBH1270810.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            17201..17569
                     /locus_tag="KRL22_000286"
     CDS             17201..17569
                     /locus_tag="KRL22_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HBH1270811.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            17594..18160
                     /locus_tag="KRL22_000287"
     CDS             17594..18160
                     /locus_tag="KRL22_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBH1270812.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            18201..18566
                     /locus_tag="KRL22_000288"
     CDS             18201..18566
                     /locus_tag="KRL22_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBH1270813.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            18667..19440
                     /gene="srlD"
                     /locus_tag="KRL22_000289"
     CDS             18667..19440
                     /gene="srlD"
                     /locus_tag="KRL22_000289"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HBH1270814.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            19789..21933
                     /locus_tag="KRL22_000290"
     CDS             19789..21933
                     /locus_tag="KRL22_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1270815.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMTSNKVNYVSDELD
                     ITSNKTDYISNELYNLSNKSIKGNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKV
                     CFDMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFF
                     MELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKF
                     ETPSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMD
                     KKSIAQAYINRRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKK
                     HGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            22021..22356
                     /gene="spoIIAA"
                     /locus_tag="KRL22_000291"
     CDS             22021..22356
                     /gene="spoIIAA"
                     /locus_tag="KRL22_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HBH1270816.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            22370..22798
                     /locus_tag="KRL22_000292"
     CDS             22370..22798
                     /locus_tag="KRL22_000292"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HBH1270817.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            22821..23585
                     /gene="sigF"
                     /locus_tag="KRL22_000293"
     CDS             22821..23585
                     /gene="sigF"
                     /locus_tag="KRL22_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HBH1270818.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            23865..24302
                     /gene="spoVAC"
                     /locus_tag="KRL22_000294"
     CDS             23865..24302
                     /gene="spoVAC"
                     /locus_tag="KRL22_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HBH1270819.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            24469..25482
                     /gene="spoVAD"
                     /locus_tag="KRL22_000295"
     CDS             24469..25482
                     /gene="spoVAD"
                     /locus_tag="KRL22_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HBH1270820.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            25496..25858
                     /gene="spoVAE"
                     /locus_tag="KRL22_000296"
     CDS             25496..25858
                     /gene="spoVAE"
                     /locus_tag="KRL22_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HBH1270821.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            26041..27057
                     /locus_tag="KRL22_000297"
     CDS             26041..27057
                     /locus_tag="KRL22_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1270822.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            27432..28274
                     /locus_tag="KRL22_000298"
     CDS             27432..28274
                     /locus_tag="KRL22_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH1270823.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            28289..28753
                     /locus_tag="KRL22_000299"
     CDS             28289..28753
                     /locus_tag="KRL22_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270824.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            28740..29912
                     /locus_tag="KRL22_000300"
     CDS             28740..29912
                     /locus_tag="KRL22_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1270825.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGKVALIKAIKVLAMCGVDILYSK"
     gene            29956..30891
                     /locus_tag="KRL22_000301"
     CDS             29956..30891
                     /locus_tag="KRL22_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HBH1270826.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(31166..33859)
                     /locus_tag="KRL22_000302"
     CDS             complement(31166..33859)
                     /locus_tag="KRL22_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH1270827.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDGGGNNGGGSTTPPDGGGTPAT"
     gene            34073..34771
                     /gene="yunB"
                     /locus_tag="KRL22_000303"
     CDS             34073..34771
                     /gene="yunB"
                     /locus_tag="KRL22_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HBH1270828.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(34983..35990)
                     /locus_tag="KRL22_000304"
     CDS             complement(34983..35990)
                     /locus_tag="KRL22_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBH1270829.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            36218..37102
                     /locus_tag="KRL22_000305"
     CDS             36218..37102
                     /locus_tag="KRL22_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1270830.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            37304..38854
                     /locus_tag="KRL22_000306"
     CDS             37304..38854
                     /locus_tag="KRL22_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1270831.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            38883..39530
                     /locus_tag="KRL22_000307"
     CDS             38883..39530
                     /locus_tag="KRL22_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBH1270832.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(39672..39932)
                     /locus_tag="KRL22_000308"
     CDS             complement(39672..39932)
                     /locus_tag="KRL22_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HBH1270833.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFRYTDKGIKNCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            40149..41432
                     /gene="hflX"
                     /locus_tag="KRL22_000309"
     CDS             40149..41432
                     /gene="hflX"
                     /locus_tag="KRL22_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH1270834.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYANLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDADLDEEDFNIYREYILEK"
     gene            41440..42117
                     /locus_tag="KRL22_000310"
     CDS             41440..42117
                     /locus_tag="KRL22_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HBH1270835.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            42203..42646
                     /locus_tag="KRL22_000311"
     CDS             42203..42646
                     /locus_tag="KRL22_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1270836.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            42951..43595
                     /locus_tag="KRL22_000312"
     CDS             42951..43595
                     /locus_tag="KRL22_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBH1270837.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(43681..44058)
                     /locus_tag="KRL22_000313"
     CDS             complement(43681..44058)
                     /locus_tag="KRL22_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH1270838.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(44058..44444)
                     /locus_tag="KRL22_000314"
     CDS             complement(44058..44444)
                     /locus_tag="KRL22_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH1270839.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            44623..45378
                     /gene="nadE"
                     /locus_tag="KRL22_000315"
     CDS             44623..45378
                     /gene="nadE"
                     /locus_tag="KRL22_000315"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HBH1270840.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            45461..46180
                     /locus_tag="KRL22_000316"
     CDS             45461..46180
                     /locus_tag="KRL22_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1270841.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(46347..47351)
                     /locus_tag="KRL22_000317"
     CDS             complement(46347..47351)
                     /locus_tag="KRL22_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH1270842.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            47617..48513
                     /locus_tag="KRL22_000318"
     CDS             47617..48513
                     /locus_tag="KRL22_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HBH1270843.1"
                     /translation="MNKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATIFGCPFEGLPKIEDAIRFAK
                     RLWENDIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHINIKSDSCNC"
     gene            48651..49913
                     /locus_tag="KRL22_000319"
     CDS             48651..49913
                     /locus_tag="KRL22_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270844.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            49989..51182
                     /locus_tag="KRL22_000320"
     CDS             49989..51182
                     /locus_tag="KRL22_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH1270845.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            51811..52605
                     /locus_tag="KRL22_000321"
     CDS             51811..52605
                     /locus_tag="KRL22_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH1270846.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            52700..54040
                     /locus_tag="KRL22_000322"
     CDS             52700..54040
                     /locus_tag="KRL22_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1270847.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            54177..55409
                     /locus_tag="KRL22_000323"
     CDS             54177..55409
                     /locus_tag="KRL22_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH1270848.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            55449..56591
                     /locus_tag="KRL22_000324"
     CDS             55449..56591
                     /locus_tag="KRL22_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH1270849.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            56602..57396
                     /locus_tag="KRL22_000325"
     CDS             56602..57396
                     /locus_tag="KRL22_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1270850.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVKDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            57407..58429
                     /locus_tag="KRL22_000326"
     CDS             57407..58429
                     /locus_tag="KRL22_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH1270851.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEIVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            58528..59904
                     /locus_tag="KRL22_000327"
     CDS             58528..59904
                     /locus_tag="KRL22_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH1270852.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(60236..60580)
                     /locus_tag="KRL22_000328"
     CDS             complement(60236..60580)
                     /locus_tag="KRL22_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270853.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            61068..62078
                     /locus_tag="KRL22_000329"
     CDS             61068..62078
                     /locus_tag="KRL22_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH1270854.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            62214..62702
                     /locus_tag="KRL22_000330"
     CDS             62214..62702
                     /locus_tag="KRL22_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1270855.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            62878..64806
                     /locus_tag="KRL22_000331"
     CDS             62878..64806
                     /locus_tag="KRL22_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1270856.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFENLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            64983..65393
                     /locus_tag="KRL22_000332"
     CDS             64983..65393
                     /locus_tag="KRL22_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBH1270857.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            65415..65717
                     /locus_tag="KRL22_000333"
     CDS             65415..65717
                     /locus_tag="KRL22_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HBH1270858.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(65934..66626)
                     /locus_tag="KRL22_000334"
     CDS             complement(65934..66626)
                     /locus_tag="KRL22_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH1270859.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(66652..67839)
                     /locus_tag="KRL22_000335"
     CDS             complement(66652..67839)
                     /locus_tag="KRL22_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1270860.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            68175..70052
                     /locus_tag="KRL22_000336"
     CDS             68175..70052
                     /locus_tag="KRL22_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1270861.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNIGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            70409..71815
                     /locus_tag="KRL22_000337"
     CDS             70409..71815
                     /locus_tag="KRL22_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH1270862.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLEFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            71843..72691
                     /locus_tag="KRL22_000338"
     CDS             71843..72691
                     /locus_tag="KRL22_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1270863.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            73352..74044
                     /locus_tag="KRL22_000339"
     CDS             73352..74044
                     /locus_tag="KRL22_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1270864.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            74041..74976
                     /locus_tag="KRL22_000340"
     CDS             74041..74976
                     /locus_tag="KRL22_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1270865.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            75124..75249
                     /locus_tag="KRL22_000341"
                     /pseudo
     CDS             75124..75249
                     /locus_tag="KRL22_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016281052.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(75271..77019)
                     /locus_tag="KRL22_000342"
     CDS             complement(75271..77019)
                     /locus_tag="KRL22_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009319968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1270866.1"
                     /translation="MPRVRKVKKSNSKNHMVWRIAVYIRLSKDDGNDESLSVTNQKKI
                     IREYLENFFEEEYILVDIYIDDGISGTTDDARTEFIRMIDDVKAGLVNCIICKTLART
                     FRNYADQGYYLEELFPLYNTRFICLGSPSFDTYKNPESITDGMDVPITGLMNDRYSAR
                     TSNDVRRTFNMKRRNGEFIGAFAPYGYKKDPTNKNCLIIDEVPAQVVRDIYRWYVEDG
                     MSKIGIVRHLNELGVPTPMDYKHSQGLNLKTPNQAKNDGMWGISTIARILSNRMYIGD
                     MVQGKQRVISYKVHKAIATPESEWFIVENTHEPIIDKVTFEMAQSLSQRDTRTAPTKR
                     NVYLFSGFLRCADCDKSMTKKTNKKNMANGETKEYTYYVCSTYALKNKDKCSRHSISL
                     EDLTEAVLNAIQVQISLVSNMAEVITEINKQEAVCNQSLRLTKQLQTKEHELEKITNV
                     IDNLYMDWKCGEITRAEYVRMKSKFEAKADSMKNAIVNLKAEIELSSKGVGNNDPYLQ
                     MFLKHKNITELNRGILAELIDTIYIHENNEITIKFNFADQHKRLLEFISNNQNTSKKE
                     GRVYTLPSLSKSTLAV"
     gene            complement(77085..77324)
                     /locus_tag="KRL22_000343"
     CDS             complement(77085..77324)
                     /locus_tag="KRL22_000343"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270867.1"
                     /translation="MNDLGNKQTTVCSDYLEAVKSINTDKALSNTERLSACIEELNNP
                     YCFLCGKTLVKVVFNEDAPTLDFCLINYFKSLKSY"
     gene            complement(77649..77882)
                     /locus_tag="KRL22_000344"
     CDS             complement(77649..77882)
                     /locus_tag="KRL22_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1270868.1"
                     /translation="MPKELTPTFTVISKACDGDETAISKILEFYDPYINQCCMRPFYD
                     DNNNLRLAVDLEMKGFIKEAIIRKILNFDIKRF"
     gene            complement(77867..78307)
                     /locus_tag="KRL22_000345"
     CDS             complement(77867..78307)
                     /locus_tag="KRL22_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270869.1"
                     /translation="MKPSELQEKTCHQFDCAIKTVIRHRAIDFYRAIRRSEKKEMPFA
                     EIMDDLLNSIGTEDTYSTDYVAVFEVCGEKVSIEDEQLARALKAIEERKRNIVLQYFF
                     IGDTDTYIGKMLDCSRANVTKCRIQALDKLKQLIEEEKEKCQKS"
     gene            complement(78582..79217)
                     /locus_tag="KRL22_000346"
     CDS             complement(78582..79217)
                     /locus_tag="KRL22_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1270870.1"
                     /translation="MLEVKNVSYAYKTKKDKTILNNVSATFEEGIFYTIVGPSGAGKT
                     TLLSLLAGLDTAVKGTVLCNGEDITKKGLNYHRKHNISLVFQNYNLIDYLTTVENVKL
                     GGSGNAEKLLEEVGIGKEYWQRNVLQLSGGQQQRVAIARALASDAHVLLADEPTGNLD
                     ETTADEIIALLKKTAHELGKCVVVVTHSKHLAEEADEILEIKNGAISFLSE"
     gene            complement(79231..80673)
                     /locus_tag="KRL22_000347"
     CDS             complement(79231..80673)
                     /locus_tag="KRL22_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005342380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1270871.1"
                     /translation="MNFFGLARRSVFRKPVKSILLLLIVFAISTLLLAGVASKNASIE
                     VQDKTRQAIGAGFLLERNAEYRTERLREYSEKIGNKEGSFGGYHQKKVVVNGVENWQG
                     WSTNEFETLDIKDIEKLAKTKGIADYNLTTAITAVNPVNFKRIEDKDVDQNADVGGVS
                     LIGNKDMKLDRNVLSGNLHIKEGRMITPEDKDMCVISEELAKQNNLKIGDKISFNDYH
                     DTVNSKVSEAEIVGIYQVDQKMSPLMQGDTYRSENVIFTDLRFPEKAEGETSPLYERA
                     YFKVEDVEAYDEVKENLQKVDINWEQYDLIDNNGNSETMSSNFNDLAKVSEMMILVIS
                     VASFVILVLVFLFWLKNRVQEVGIFLSLGVPKFRIIGQIWSEAIMIAVLSLMLSFAVA
                     PAVSKVTANYLVSQQVQQMQEEEKNNEGKVSTEYVAPKQDVQSISVEVTPEMYLLDGA
                     SVLVLITASVLVSGIVILKRNPKDILSEMS"
     gene            complement(80677..81900)
                     /locus_tag="KRL22_000348"
     CDS             complement(80677..81900)
                     /locus_tag="KRL22_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1270872.1"
                     /translation="MKFYQLGFRYLQRKKGKTILLLIVLILVNSMILGTSMILRTTNE
                     SKQAMQEKTNSKIVAEITSKDSKITENEVNKIETLEDVSSINRIGRQEVFPNNFAPVT
                     LNTSTNEENLKIALLSYDDLEKDSPFSEMQYRLASGDYIKHEKKGAVINTNLANQNGL
                     KVGDTIELSTENGTKVSVQIIGIFMSAGNAEKDQPSETTAVNRIENQIFIDNSTYKEL
                     FKEAEFEKICIYSKRPEKLDVLETSLQKIFGNDVALSTSDTLYQQMSAPLEQISKVAN
                     LMLVLTLVTGTVVVSLLLCMWMRTRQKEVAIFMSLGKTKIEIFLQTLLEAGSVFTLSV
                     LGATAIGKLFSGVLQNIITSSESVTENLKVVLQIQDIGMLFLLGGAVILVALCCSILP
                     ILRANPKDILAKMEG"
     gene            complement(81912..82406)
                     /locus_tag="KRL22_000349"
     CDS             complement(81912..82406)
                     /locus_tag="KRL22_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitinase"
                     /protein_id="HBH1270873.1"
                     /translation="MKKTNISKFIAVGLCICALTGCGASPDEKPDTSNPIVNSNTNEE
                     NANGSSENKGNDILDSANLIGSVLEFTDNGCSVSQAKEIEGGAGIKSEAAGLENKDNA
                     VSVTYNPDCEFVVATLNKQSGVTNVTTGSISDVKKQSEVYLYGEFADTNHFNATKVVV
                     ARWE"
     gene            82601..83287
                     /locus_tag="KRL22_000350"
     CDS             82601..83287
                     /locus_tag="KRL22_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005342376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1270874.1"
                     /translation="MKILLLEDDLELCKNIKISLEKENYMVDCCNDGETAMLYALNTD
                     YAYDLAIVDRMLPIIDGLTIIKSMRRKGISIPILIITAMSTLDNRVEGLDGGADDYLV
                     KPFHIKELLARVRALTRRPANIQLSPKLQYGDLTFDKDSRTLSTPVNSILLTSKETEL
                     TFVFMQNPETLFSREQLILKIWGSSSEVETGNVDSYISFLRKRLKELKSSCKITTVYG
                     AGYKLEKETC"
     gene            83281..84573
                     /locus_tag="KRL22_000351"
     CDS             83281..84573
                     /locus_tag="KRL22_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1270875.1"
                     /translation="MLNNLYRKLHILFASSVMLIITLVISFVVANTVHTEKINESTLF
                     QRLTTLLIYQVESASSDMDKALKTYEESYHIFSLITDTRGNTIYQSDFPFPTSADNLL
                     HDVEMQISTQPLSQTESNTTSQGGFLEIRGTHHDTYFVIPATIRTANDTVYHATFLYQ
                     TASLTDILQKTLPIYLLIWFLACIVVIVLTRYLLKKSFAPTERILQSQKDFVATASHE
                     LKSPLAVMISNTDMLLDNVSLNEQAKQAVQTVDFECMRLSRLVKDMLLLASSDAKTWT
                     LHKSTINVDTLLITLYETYEPVCMKQNLKLKLHLSEESYPAMLTDKDRLFQILCVFMD
                     NAIQHSKNNSLIEIEVIATEKNIAFSVVDHGQGISDEDKQYIFDRFYSGDKSHTNKSN
                     FGLGLSIAKELTQMLNGAITINDTAGGGATFTVKFPLK"
     gene            complement(84619..84843)
                     /locus_tag="KRL22_000352"
     CDS             complement(84619..84843)
                     /locus_tag="KRL22_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270876.1"
                     /translation="MIGLKKRDIKKALKAGAKAGGVSLADVRADIEATIDEAMNSTAP
                     EVQANFKKYFGNKRPTPEEYIYKITKKTKI"
     gene            complement(84889..85584)
                     /locus_tag="KRL22_000353"
     CDS             complement(84889..85584)
                     /locus_tag="KRL22_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1270877.1"
                     /translation="MCTRFVYNGIDKIVGFNFDIDLSVWDHTVITEENRFYIGIKMPD
                     GMYHSFHGINKNGNVGTLLYVHGNENARYIESEDCITISELTEKFIKAEISFDKALDI
                     VKKKKIIYAPDATMQAMLSDKKGRVLIIEPGIGYRYEQENFSLITNYSILKPDITKPY
                     IVSGDTRYEVAKELLAGYDKDFSVNDAFKVLKSVSQKDLWATRVSFVYSTEKNKVYYV
                     LNNDFSNVFEFQF"
     gene            85762..86319
                     /locus_tag="KRL22_000354"
     CDS             85762..86319
                     /locus_tag="KRL22_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005946872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1270878.1"
                     /translation="MKTTKEAVIKATSDLADEKGLNNVSLKAVAQKLNIRTPSLYNHI
                     ESLDNLLLEVAHNGMRDMNERMMKIAVGKIGKEAIKLVSIEYLNYMIEHPGVYETIQW
                     AVWHGTEETATIFNNYLSLLTTLIQSCSLNKDKTLEILNMLTGIIHGYTTLQLGNAFS
                     ASDKVRFELAEAIDTLLVGIFQKYK"
     gene            complement(86366..87277)
                     /locus_tag="KRL22_000355"
     CDS             complement(86366..87277)
                     /locus_tag="KRL22_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1270879.1"
                     /translation="MFKKNKKQTETIKEPKEKKVRTVKVGTHKKTVIALWVVLIASVS
                     FGVYKNFTAIDQHTTHEKEIIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIEARTQA
                     INGYLTKELQDLNVDTIRMDIPTSSTVTDVIVWSIEQSGTDTFSATYEVDQQIKEGEQ
                     ARNVKATYTVKVHVDADGDMVIVQNPTLAPAIEKSDYEPKTPEADASVDADTVNDATA
                     FLETFFKLYPTATEKELAYYVSGNVIEPIGRDYLYSELVNPIFTKDGDNVKVKVDVKF
                     LDNQTKATQVSQYELALHKDSNWKIVG"
     gene            complement(87293..88300)
                     /locus_tag="KRL22_000356"
     CDS             complement(87293..88300)
                     /locus_tag="KRL22_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH1270880.1"
                     /translation="MKLKHIALIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYAREYGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGIDDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYAELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYADLSSSYWQQHLIGAGRVK
                     Q"
     gene            complement(88297..90492)
                     /locus_tag="KRL22_000357"
     CDS             complement(88297..90492)
                     /locus_tag="KRL22_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1270881.1"
                     /translation="MKERIKGAFTKKKIFHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTENGFGSTGFYVGSLLLIIL
                     IIGIYVAYTGLIKRETSKAVQAVINFLVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEKIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLFIFNIGITIFVFLLT
                     GIMMLSQILFIIFAMFLPISFLLSMIPSQENLAKQAIVKVFNTIMTRAGITLIVTVAF
                     SISSMFYNISKEYPFFMVAFLQIVCFAGIFIKLGDLMNMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMERRLAGAVTAGGVAGAVAGNTISNRKPTRNTATKDSRGNTTSSMGQR
                     AGSKVGAVLDTRNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKRGMVQE
                     QQSRQTGRLEKQEQHKKNIADKRMELQKAQEARQVQRKADGSATTGATRPHERPATAS
                     IIPKPSAEKTQEVKRPATATTSKASEPVKTNVIKERPLSSGASDRKATQSAQPVHRQN
                     VEKVVSQETRQNYTKDRRTKVHQTQSVQKNQQTTEKTRNLVMKKGQKKK"
     gene            complement(90492..92942)
                     /locus_tag="KRL22_000358"
     CDS             complement(90492..92942)
                     /locus_tag="KRL22_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1270882.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIVQSREGKIHALQIATESSIRSQQEQSKKLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFTEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLMEHLYGRDGIAYEDYEYQLPKKKLQKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIMENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPAGKRYINDYVQYVKSDFLAGLGFGATQQLGETTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSDSRGLLHVIDELRREDTLISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSSGDVAKESLKNNIGLK
                     FAFRSTDLGEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(92920..93318)
                     /locus_tag="KRL22_000359"
     CDS             complement(92920..93318)
                     /locus_tag="KRL22_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1270883.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDIPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQTLNETITAVRSVNYVPDKIY"
     gene            complement(93428..93931)
                     /locus_tag="KRL22_000360"
     CDS             complement(93428..93931)
                     /locus_tag="KRL22_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1270884.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIAIGEYVSIEELNEMYEMIEELPDYIVECLDEFISYYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIETSR
                     GMCEIPY"
     gene            complement(93949..94452)
                     /locus_tag="KRL22_000361"
     CDS             complement(93949..94452)
                     /locus_tag="KRL22_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1270885.1"
                     /translation="MQETRVLVETRGTTGEETKSYWFDLPIDVAEFEEKLGVGAESGD
                     YRIIEKVLPFADEVHEHTSVYQLNELDFMYRQLSSDMQEEYVSLLTVYENLEALYICR
                     NVITVYPDCKSMIDVAKQKLMNDPTFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(94371..94667)
                     /locus_tag="KRL22_000362"
     CDS             complement(94371..94667)
                     /locus_tag="KRL22_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1270886.1"
                     /translation="MNDIFKDMQANVGCEYISDLPSYKRKVWHEMKRLNPADYEERQL
                     EDFSKYVFGMSYQTLKDVMKQQKGREEQCRKQGCWWKREEQLAKKRNHTGLTCR"
     gene            complement(94759..95067)
                     /locus_tag="KRL22_000363"
     CDS             complement(94759..95067)
                     /locus_tag="KRL22_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009262127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270887.1"
                     /translation="MKKLYCMNCGAQIKGGIPNKCSCGAEFDLADRKNIKKIITSIIF
                     FVILMSPLLILIHFGRQYLQASIILYALLLILGVFWYRIVQTILVRLGLVTMTNIEIK
                     "
     gene            complement(95308..95637)
                     /locus_tag="KRL22_000364"
     CDS             complement(95308..95637)
                     /locus_tag="KRL22_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBH1270888.1"
                     /translation="MKLVGSRKLTWGICGIGILLALVGVLFLPQIIPVHFANGIADDF
                     GNKIEIFLFPILLLIITILTGKEKIKYFLTHSKTFLTDIQYNLMIDGVLGIVLIAEIY
                     VIYASFV"
     gene            complement(95724..95885)
                     /locus_tag="KRL22_000365"
     CDS             complement(95724..95885)
                     /locus_tag="KRL22_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270889.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALIAVGLVFNAGGVKDVLL
                     ELFNKIIGA"
BASE COUNT        34377 a        13173 c        17148 g        31205 t
ORIGIN      
        1 ttattttatc atatattgta ttttataata tatttttgta gggtatagta taagtatatt
       61 atattttact ataaaaattt gtaataaagt gaaaaaacta gcttttcatg aaataatatt
      121 ttataattta agattgtctt tttaataaag attaacaaaa aaaatactat aattagtggt
      181 ataatagtta gagttgaaga ttttaaataa aggtaggtgt aattaagttg gaaatatact
      241 tagacaatag cgcaactaca aaaccttatc aagaagttat agataaaatg gtttatgcac
      301 ttaatacgga atatggaaat ccttcttctg tccatagaaa aggtgtagaa gttgaaaaag
      361 ctataaaaga agtaagacaa gatatagcta aatctctagg agcgaaagaa aaggagattt
      421 attttacatc aggtggtaca gagtgtaata atactataat aagaggtatt actagtttaa
      481 ataaaaaaag aaaaaatcac ataatatcta ctaacataga acatccttct gttttaaata
      541 cattaaaaga tttagaagaa gatggttttg aagtaactta tttagaggtc ggaaaagatg
      601 ggaaaataaa tatagaggat ttaaaaaatg cgataaagtc aactacatgc ttagtaagca
      661 tgatgcatgt taacaatgaa ataggaacta tacagccaat aggtgaagtt ggaaagtatt
      721 tgaagggttt aaaagaaaaa atttatttcc atgttgatgc tattcaatca tatggaaaaa
      781 ttaactttag accatctaaa tacaatatag attttatgag tgtaagtgca cataaatttc
      841 atggtccaaa gggaattgga tttatgtata taaaagaaaa taatcgcctt aagcctatgt
      901 taacaggtgg tggtcaggaa attggaatta ggtcgggaac agaaaatgta cctggaatat
      961 atggtcttgg agaagctgtt agaatactaa acaaagattt agatgctgtt atttcgaaag
     1021 tagataactt aaaaaatata ttaaaaaatg aaataattga taatatagaa gatataaaaa
     1081 tcaattctcc agaagatgga gtatgtcata tattaaatgt atcatttaga gggacaaaag
     1141 gagaagtttt acttcattac ttagagcaaa aaggtattta tgtatcaact ggctctgcat
     1201 gttcttctaa aaagaaaggt agttacgtat taaatgctat aggtcttaca aatgaagaaa
     1261 taaatggaac aataagattt agtttatctg atatgaatac agaagaagaa atgttagaag
     1321 ctgtgaaagt tttgaaagaa tcaatttgtg acttaaggtc aataatgaaa agaaaataaa
     1381 gaatactgta taaatagtga taataaatta gtttaagagg tgaaatggtg tataatatat
     1441 taatagtaaa gtatggagaa attggagtaa aaggaaagaa tagatatata tttgagaata
     1501 ggcttataag aaatataaga aatatgttaa aaccaattgg aagatttaat gtatataaag
     1561 agtatggaag aatatatgtt gatttagaag actatgatta tgaagaagta attgaagaag
     1621 ttagaaaagt atttgggata gtgggtgtgt gccctggagt aagagctaaa aaagattatg
     1681 atacattaaa agaaatagct ttaaaaatgt tagaagaaaa aatagaggct ggatataaaa
     1741 cttttaaggt agagtcaaga agaggagata agtctttcgg gttgacttct caagaaatga
     1801 gtatggatat aggtggatac ttattatcaa aggtaggaga taggattaat gttgatgtaa
     1861 gaaatccaga agttaaaata aagtgcgaat acagagaatt tcatactatg gtctatagtg
     1921 atactatacc tggatatggt ggattgccac ttggaacgaa tggtagagct atgtctcttt
     1981 tatcaggagg tatagatagt ccagtagcta catggatggt tgcaaaaaga ggtatggaag
     2041 tagaggcagt tcactttcat agttatccat ttacaagtga aaggtcacag gaaaaagtta
     2101 aggatttagc taaaatactg gcaaaatact gtggtagagt aaggcttcat aaagttaata
     2161 tcttagaaat acaaaaagca attggcgaga attgtaatga agaagaagct actattcttt
     2221 caagaagatt tatgatgagg atagcgcaga ggctttctga aaaaagacat tgtgatgctt
     2281 taattacagg tgaaagtatt gggcaggttg catctcaaac tatacaaggg cttacttgta
     2341 ctaatgccgt tgtagactta ccagtgttta gaccacttat agcaatggat aaatcagata
     2401 tagttgatat agccaaaaaa atagggactt ttgaaacatc tatagtgcct gaagaagatt
     2461 gttgtagtgt attttctcct agaaagcccg tcactaaacc tagattagag aaaatagaaa
     2521 aatctgaaac agcacttgac attgaaaaat tagtacagga tgctattgac aaaatagagg
     2581 tagaggatat tgagttttag catacgagtt atttaattac taaattgaat attgagtata
     2641 ttagtagttc tgtaagtata ttagtagttc tgtaagtata ttagtagttc tgttgaaagg
     2701 atttatgtag acaatttatt aatatgtagt atttaaaaat aagtactata attttattta
     2761 atgggaatga ttattatgaa taaaaagggt tttacattaa ttgaattgtt ggtagttata
     2821 tctataatag gaattttagt tatagtagct gttccagcgt tatttagaaa tatagaaaaa
     2881 agtaaagcag ttacatgtct ttctaataga gaaaatataa agactcaaat tgttattgca
     2941 atggctgagg aatcaagtaa agacaagaat gaagtcataa aagaggtatt agaaaacaaa
     3001 gatggtaagt actttgaaac agaaccaaag tgtaagtcag gtggaatata ttcagcaacg
     3061 tttgatgatg gttatgatgg aataactgga atagaaagca ttgcaaaagt gtatgttact
     3121 tgtacaaaac atccagacgg tgttgaaatg gctagggatg tgcatcaaag tatgaaagat
     3181 ttgattgcat catttgcaca agacccttct ataataccag gagcctcaaa gggtaatgat
     3241 gattttagaa aatatttatt agacaataaa tataaaaatg ggtggcctac aattccagat
     3301 gaatttaagg caaaatatgg attaagtaag gatacactat atatacaacc atatgcatat
     3361 aatcctacta aatctgatgc tactgtagtt gtatttgcaa ataataagac tgggggtaat
     3421 tggtatactt ccctagttta cgattatgat gaaggtagat ggtataaagg taaaaatggt
     3481 atttctgttg caggtaggtc atgggatgtt gacacagata gtgttaagtc tgtaaaaaca
     3541 gagattcatt ctaaagaggg atggggtcct ttaaattaat atatcatgtt ttattaatct
     3601 ggtattgatt aaactataga aaagagcagt ttctatagat gacgaatacc agattttcat
     3661 ttatatatat aattgagata tattaaaagt gtttatattt ttaagccttc acatacaagc
     3721 taaaaataat tataataata ttgtaaagaa atttaattat aagattaatt ttctgaagat
     3781 ttagtatttg tactaagaaa tacataaaaa ggggaataga tatgaataat aattttcaag
     3841 acaaccaaac aataaattta atacaaagtc gtagaagtat acgaaaattt acgacagaac
     3901 aaattagtga tgagcaagta aacacattat tacactgtgc atttgcagca ccttcaggat
     3961 gtaataaaca gccttggcac ataactgttg tgcaagacca gaaactttta aaagagatta
     4021 gtgatgatac tttatctagg attcatgagg tgagtaatgt tgagataaat aaaaacttta
     4081 agttatttta tggtgctcca accgttttat ttatttctta tgatgaaagt agttcatggg
     4141 ctccatatga tataggaata cttacaggga atataacaac agctgcacaa gcactagggc
     4201 ttggaagttg tataatagga atggttagag gtttatttac acctgttgaa caaggggata
     4261 ttgaaggtct tgtgagtgta ttggataaag aagatgtaaa agaatcagag tcaataaaga
     4321 tgaagtttga tacaaataaa aaatacagag aactacttga tataccagaa gggtattctg
     4381 taccatttgg tattgctgta ggtattccag atggaaattt accaaatgct agagaggtag
     4441 tttacaaagt ttccagagtt taggataaag tattgcaaga accaatcagt tacttgaaga
     4501 attaaatcag taatatacaa ataaattgat ggaagaggaa gctatttaaa aagtagttta
     4561 gatttttcgt tgtaaaataa ttaaataaag aataaggtga taagtatttt atttattatc
     4621 ttattctttt ttatttttgt tttgtagaat gataaaaata aggattaagt gtaataaaat
     4681 agaaaacaag tatgttaatt ttaagtatat gctttaaaat ttatccaagt taaaaattta
     4741 agatatcttt tcagtataat ggaaaaaatg tcaaaatatt gaaataggga aaaaatagtg
     4801 atataataag aaaaaataga gaaaaaagta acccttagtt gtaaaaaagt tactatttat
     4861 tgaaaattta gatatttttc taaaaattat ctatgttaat agttaaattt atgaacattt
     4921 tttgttttta tgttaggata tttcttagaa atgaaatact tcttaatttg atttgatatg
     4981 tatattttta tagctatttt attataaaaa aaaagaaccc tttacaacaa atggaaacta
     5041 tggatgtaat aattaaaata aaaaatatta ttttatattt ataaacattg acattctaat
     5101 tttgtagtgt aatcgtattt tttattaatt cttacaaaat caatgaaaat aagtatatcc
     5161 attttaaagt acataaattt aaaaatccag aaaaatatac ttaaattatg taagtaaaag
     5221 aggggttgaa tcagttgaaa atgtaatatt agcaaatagt acatcaatcc tatataccct
     5281 gtaagcaact ctattttcat gtactaaaaa tgtacctatt ttattaactg aaaagaataa
     5341 attaaatgta agtacataag aagatagaaa aaattaaaaa caaaaaatat ttatataaat
     5401 aaatataaaa aatgatataa tccctattaa aaaatttata gatgatgaag aaatatcaaa
     5461 atcttatatt ataggaagag acacttcttt gccaaaatct atagaaaagc aataccaaat
     5521 ccaaagagaa taggcggaga aaaaaataaa ataaattcaa gagtaataga aaagttttat
     5581 agaataaaga actgagaact ctttatataa tgaaaaatag aattttaaga gaaaatgatt
     5641 taataaatga tttaacatgg tgttttagca ggtaaaaata aatcaccagt aatgattata
     5701 gaaaaattac tttatgaatc tcaaaaaact tagttaagag taagagattt gataagataa
     5761 ctaaagttgg ggaaatgtgt ttgatgagat aaaaaattag taaaatagta taatctaaat
     5821 aaggatattt tgttgattaa actacactaa tagtaatatt gtagggggaa aagatgagag
     5881 aagaatcgaa ctctttaagt ttagaccata tagaaatttt ctttgaactt ttatctcaaa
     5941 gtacagaaga ttatatattt ttttgggata taaataggaa taaatttaaa atttcttcag
     6001 caatttttga tgaatttaac ttaagtaaag agatagaatc tgatttggtc aattgttgga
     6061 gtaaaattgt ttatccggat gatgttcaaa tatggaaaga tgatatacaa gaattactac
     6121 atggaaaaaa aggtgagcac aatttagaat ataggttgat taataaatat gaagaaatag
     6181 tatggatttc ttgtagaggt aaagtttatg tgtcggatga cccaaaaact atatttctag
     6241 ttgggagaat aaagaatatt ggtgaaaaaa ataaatttga ttctatcaca ggaacgtgga
     6301 atagagaaca atttgaacat agaataaatt atcttataaa agagaaaatt tataaaaatg
     6361 gtgctatgtt tatcatggat attgataatt ttaaaaatat aaatgagaaa tatggacatt
     6421 cttatggtga caaagtattg cgtgcaattg ctactgaagt attagaatat cttccaaaag
     6481 atgtaagatt gtataggtta gatggagatg aatttgcatt tttttaccct atgtgtacta
     6541 aagaaactat agagaaaata tatgaaaaga tacagatgta tacaaatact cagcatgaaa
     6601 ttgaatcaaa taagtactat tgcacagtga ctgcaggagt tgctatgtat ccagaagatg
     6661 gagataatta tttagattta tttaaacatg ctgatattgc attggatata gcaaaaatta
     6721 gtggtaaaaa tagaattaag tttttttcac aagagctcta tgaaaataaa ctaaaggtaa
     6781 tttcaatgca acaaaaacta agagagtgcg ttgaaaataa ttttaatgat tttgagttgt
     6841 tttttcaaac ccaggtaaat gctgttacaa aagaggtaat aggggcagaa gtacttttaa
     6901 gatggcattc aagtacttat ggagaagtat ctcctgttga atttatacca atactagaac
     6961 agagtaattt aattatacca gttgggaagt ggattataaa agaagctgta aaacagtgta
     7021 aagaatggca taaaataaat ccagacttta aaatatctgt aaatgtatcg tatattcagt
     7081 taaaggaaga tttttttaga gattttatag tagaatgttt agtagagtat caattaagac
     7141 ctgaattttt aattttggaa ttaacagaga attgttggat accagatata aatttactaa
     7201 atgataaatt tattagttta aagggtatag gagtatatat tgcgatagat gactttggta
     7261 caggatattc atctttaaat taccttaaag aactgtctgt taatataata aaaattgaaa
     7321 gaagttttgt taagaatatt acatataata gttatgaata tacttttctt gaatatatta
     7381 ttaaattagc tcatattata aatttaaaag tttgtgttga gggaatagag tcttatgaag
     7441 agtatgatat agtaaaaagc ttaggtgtag atattattca gggtttttta tttggaagac
     7501 ctgtaagtgc ctctgaattt tataaatttc aactatcaaa gtgatgtata taaaatgaga
     7561 tatatagtat ataaaaatag ggcaaagtgg aagttttgaa gtttattaaa aatttacact
     7621 ttaccctatt ttgttatgtc ttctataaag gattaatata ctacactaac tattatatac
     7681 tttcactcca aatttagaga ttatttcact agctttttgg acatcttcct tagtggcatc
     7741 aggaacatct tttagttcat aatcgatacc taaactttcc catttgtgta ttcccataga
     7801 atggtatggt agcaattcaa atctttctac atttttcaat gtagctacaa attgacctag
     7861 tttttctaaa ttatctatat catcagtaat gccaggaact aaaacatgtc ttatccatac
     7921 aggaatattt cttgattcta agtgtctagc aagttttaat gccttatcca taccaacacc
     7981 agtcaaatca atagattttt cctcaaccat atgttttaaa tcaagtaaaa ccaaatcagt
     8041 attatctaaa actgggtcta tagtttctat atctacaaat ccagatgtat ccaagcaagt
     8101 gtgtatatca ttttcttttg cttttttaaa taattcactt aaaaattctg gttgaagagt
     8161 ggattcacca ccagaggcag ttatacctcc accagaaaac ttcataaaag aagtatactt
     8221 aagagcatcc gttattattt catcaactgt gtattctttt cctgatttaa tatcccatgt
     8281 atccctgtta tgacagtatt tgcatctaag aggacacccc tgaaaaaata atatatatct
     8341 tattcctggt ccatctacag taccaaacgt ttctatagaa tgtatctttc ccttaatcat
     8401 agagttcacc tcacaatata ttttaataac cttatcaata gttataatat ttctctaaaa
     8461 aaggccatct tataccagaa ataattcaaa tataagatag ccttttattt ttatttttta
     8521 cacagtagta atcttagtta aagtataaaa atttaaagac taagccattt taccgtggaa
     8581 tgttctgttt ataacatcta attgttgctc tttagttaat tttatgaagt taactgcata
     8641 tccagatact cttatagtta attgtggata ttcttctgga tgttccatag catcttctaa
     8701 agtagctcta tcaaatacat ttacatttaa gtgatgagca ttttgagcga agtatccatc
     8761 catcattgca gaaagattgt ttattctttc agtcatatct tttcctaaag cagcaggtac
     8821 tatagagaaa gtattagata taccatcttg agcatgttca tatggtaatt tagcaactga
     8881 agataatgaa gctaaagcac cattagtatc tctaccatgc attgggttag caccaggagc
     8941 aaatggagca ccagctcttc taccatctgg tgtattacca gttttcttac cataaacaac
     9001 atttgaagtt attgtaagta tagattgagt tggataagaa tttctataag ttttattctt
     9061 tcttatttta ttcataaagc tttcaactaa ctctacagct atactatcaa ctctgtcatc
     9121 attatttccg tattttggat aatctccttc tatttcaaaa tcaacagcta ttccttgttc
     9181 atttctaata gttttaacct tagcatgttt tatagcagat aatgagtctg cacaaactga
     9241 taacccagcc ataccacaag ccatagttct aaatatatct ctatcatgta atgccatttc
     9301 taatgcttca taagaatatt tatcatgcat ataatgtatt acatttaaag tatttacata
     9361 taatgttgct aaccaatcag tgaatggttc aaatttactc ataacttcat cataatctaa
     9421 gtactcagaa gttataggtt caaatcttgg tccaacttga acaccagatt tctcatctac
     9481 accaccattt atagcgtata ataaagtttt agctaagtta actctagctc caaagaactg
     9541 catttgttta ccaattctca ttgcagatac acaacaagct ataccatagt catctcccca
     9601 gtatgctctc attaaatcat cattttcata ctgtactgaa cttgtatcta tagatacttt
     9661 agaacagaaa tctttgaatc cttgaggtaa tttagttgac catagaactg ttaagtttgg
     9721 ttctggagaa ggccctaatg tatatagagt atttaacatt ctaaatgagt ttttagtaac
     9781 taatgttcta ccatctattc ccatacctcc tatacactca gttacccaag ttgggtctcc
     9841 agagaatagg ttattgtaat caggagttct taggaactta accattctta atttcataac
     9901 aaaatggtcc atatactctt gtaattcttc ttctgttacg attccagctt ttaaatctct
     9961 ttcaaagtat atatctaaga aagtagatgt tctacctaaa gacattgcag caccattttg
    10021 gtctttaaca gcacctaaat aaccaaagta taaccattgt acagcttctt ttgagttagt
    10081 tgctggtttt gatatatcaa atccataaga ttcagccatt tttttaagtt catttaaagc
    10141 tgatatttgc tcagttattt cttctcttaa tctgataact tcctcatcca tgcaagaaac
    10201 ttctaatgat ttcttttgct catttttatc ttctattaaa gcatcaacac catatagagc
    10261 aactcttctg tagtcaccaa ttattctacc tctaccataa gcatctggaa gacctgttat
    10321 tataccagat tttctagcag ctctcatttc tggagtataa acgtcaaaaa ctccttggtt
    10381 gtgtgttttt ctgtatttag taaatatatc ttttatttct gggtctaatt catatccaaa
    10441 agcttcgcat gaattttcaa ccatctttat accaccatat ggcatgacag ctctttttaa
    10501 aggggcatcc gtttgtaacc caactattgt ttctaattct ttatctaaat atcctggagc
    10561 atatgcagct attccagaaa cagtttttgt atcaacatct aaagtaccac cattttctct
    10621 ttctttttta aataggacca ttgcttcgtc ccataatttt ttagtatttt cagtggcacc
    10681 agctaagaaa gagtcatttc cctcatatgg agaatagttt aattgtataa actctctaac
    10741 atttatttct ttagtccatc ttcctgtttt aaatccttgc catgcattca ttaagtattt
    10801 cctccttaga tttaaatgat aaataatact attaaaatta atttttatat acttaattta
    10861 ttttatatat ttttttaaaa atatattttc taatataata atagcatatt attcgtatcc
    10921 tgtatacata aaaaataaaa aattgtcgct ttaaagtata aaacagatta tatgttaata
    10981 atgtggtgaa attataccca tatataaata aaataaaaca aataaatagc taattaagga
    11041 gaaaatattt tttatttttt gtttaggata aataaatttt attatggaaa aaagaaaaag
    11101 catacatctt cacaaactga atatttattt aataggggga ggtgatagat tgtttatcac
    11161 agtggtatta tttttagtag gtttcctatt aattactaaa ggcgcagata tctttataaa
    11221 ttgtactgta gagataggta aaaaaacgaa tatatcagaa attatacttg gagctactat
    11281 agttagtttt gcaacaacat tacctgaatt tacagtgtct ctacttgctt ctattgatgg
    11341 tcatactact atgagtttag gaaatgcagt tggttctata atatgtaata cagggttagc
    11401 attagggttg gttgttttta taagtccatt taatgtagat aaaaaaatgt ttttttctaa
    11461 gtctttacta ttaatagtat ccgttatagt tttaatttta ttgagtttag atggagttat
    11521 aacaagaggt gattcattat tacttataat aatattaatc ttttatatgg ttaataatta
    11581 tagaagtgtc gttggaaaat ctgatactaa aaatagaaat attaaaaata acactattaa
    11641 agacatatct actaaaaaag ggaaaaatta tagaggtttt tccgtattag aaattgtaaa
    11701 aatactatta ctttttgcta caggattgat aatgatgata ataggttcac aaatccttat
    11761 agagagtgga gtaataatag ctagtttttt aaatatacct caaggtatag taagtttaac
    11821 tataatagca cttggaactt ctctgccaga gatagtttcg tcgattactg ctataagaaa
    11881 aaatcatcat gaaatatcag taggaaatat tttgggtgca aacatattga atatagtatc
    11941 agtaatagct gtatcagcaa taccaaataa cataccaata ctatctcaaa atagacaatt
    12001 ggatatacca ttcatgatat tattattatt aatagtaata ataccaacac ttaaatctaa
    12061 taaacttagt agaatacaag gtatattgat gttattcaca tattttctgt acatatcaat
    12121 tttgtatttc atgtatatta tttaactata ctgtttaaaa tattaattgc agaatatcct
    12181 aaaaaagtat ataatggata ggttaagatt aattgataac ggagaggaat aatatatgaa
    12241 tataacaaag tttgaagatt taccaataag tgagggaata aaaaaagcta tagctgaaat
    12301 ggggtttgaa gaaccatctc ctatacaagc acagtctata cctgcgattt tgtcaggtaa
    12361 agacgttata ggacaagctc aaactggtac gggaaaaaca gctgctttta gtatccctat
    12421 actagaaaca atagacccaa ataatagaag tttacaagct gtagtgcttt gtccaacaag
    12481 agaactggca atacaagtat caacagaaat aagaaagtta gctaagtatt cgcacggaat
    12541 aaagacatta cctatatatg gtggtcagcc aatagataga caaataaaat ctctaaagag
    12601 tggtgtgcaa gttgtaatag gtacaccagg acgtacaata gaccatatca atcgtaaaac
    12661 attaaagatg gataatgtaa aaatgattat attagatgaa gcagatgaaa tgctagatat
    12721 gggatttaga gaagatatag aaatgatttt aagtaagatt ccagaagaaa gacaaacaac
    12781 tttcttttca gctactatgc caagaggaat tttggaatta actaagagat atcaaaaaga
    12841 cccagagcat ataaaagttg ttagaaaaga acttacagtt tcaaatacaa agcaatacta
    12901 tatagaaact aggtcatcaa ataaattaga agtattatgt agattagtag atgtatatga
    12961 ccctaaacta tctgttgttt tctgtaatac taagagaaaa gcagacgaat tggtaggaga
    13021 tttacaagca agaggatatt ttgcagatgc attacatggt gacttaaaac agactcaaag
    13081 agatatagta atggataagt ttagaaatgg tacaatagat atacttgttg ctactgatgt
    13141 tgcagctaga ggtatagatg ttgatgatgt tgaatgtgta ttcaactatg acttaccaca
    13201 agatgaagag tattacgttc atagaattgg tagaactggt cgtgctggta gagaaggtat
    13261 gtcatttact tttgtatttg gaaaagaaat gagaaagatg aaagatatag aaagatatac
    13321 taaatctaaa ctgataaagc ataatatacc aacaataact gatgttgaag agaaaaaagt
    13381 aggtactttc tttgcacaag ttaaacaaac tatagaagaa ggtcacttaa ctaaacaatt
    13441 acaatggtta gaaggttttt gtaatgatga agattatgca atggttgata tagctgctgc
    13501 acttgtaaaa ctatctctag gtgaagaaat gaaagaagaa ataatagaag aaaaacctag
    13561 aagagagcgt ggagatagaa aaggtggtac tggagctaaa gatggtatga ttagattatt
    13621 tatcaatatt ggtagaaatc aaagagtaca agcaaaagat atagttggtg ccatagctgg
    13681 agaagttgga ataccaggta aagtagtagg tactatagat atatatgata agtatacttt
    13741 tgttgaaata cctaaaaaag atgcaaaaac agtaattgaa aagatgaaag atattaagat
    13801 aaaaggtaat aagattaata tagaaaaagc aaataagaag aaaaaataac gtatagtata
    13861 caaaactata attagaaaat atataaaata atatattgga tatttaaaaa gcctgatgtg
    13921 ttttcaaaac agatagtaga taatctgtaa gagttaacag cataaggctt ttcttgtttt
    13981 atatgatgtt ataattttcc agattgttgt gaaaaatgta tattagttcc tttttttcaa
    14041 atctgatttg aaaaagagaa tattaattat ctatatagtt tagattataa taaaaaatgt
    14101 aagataacaa aggggagaaa aagatgtcaa tgacttatat ggaccctagg gtttttttga
    14161 ttttagaaat ggtgttagaa gaagacacaa atactctaga acaattttca aatgttttgg
    14221 gtgttagtac taggactatc agaaactata taaaccagat taatcgagaa ttaaaaggtg
    14281 gtattgctaa aatagttaaa aatgaaaaag gtacatatag tataagaatt gaggatgaaa
    14341 gtaaattaat tgagattgta aattttaata gaggaaagct atcaaatttt ataaatttaa
    14401 attcacctga tgaaagaata aattatgttc ttgatatttt aactatgacc aacaatccaa
    14461 ttaccataga tgatttggct gaagagatat gtataggaag aacaacatta ataaaggatt
    14521 taaaaaaagc agacagaatt ttagctgaat atgatttaga attaaaaagg aagccaaata
    14581 taggtatgat tttagttggt gaagaaatgg atataagatt attaatcctt gatagattgt
    14641 atgaaaatta tattgatgtc ttggaaaacg ttaatcagat aaatttagtt aaagattatg
    14701 atattgaatg tcttagagat gaattaaaaa agttatttaa aaaagaagaa ctctacataa
    14761 cagaacaggt cttgagagat gttgaaagat atataatcat gtctgtctta agaaatctaa
    14821 atgggtacaa atttgaaaag atagataaga gatttgaagt gataagatgt tcagatgaat
    14881 atactttagg attaaagctc aaagctttat tggaaaagat atttaatata gttttaaatg
    14941 aaaaagaaac catatttttg acaatgccat taataggtag aaaagctcct agtacaaaat
    15001 tagcacttag cagtataaag ataaatgata gcgtaaagga agttgtagat gaagtaacta
    15061 gttttttatt agagacctca gggattgatt ttaaagaaga taaaaagctt atagaaaatt
    15121 tggaatatca cttgtatttt gcacttaata gaatgagatt caacataagg gtaaaaaatc
    15181 ctcttttaca agaaataaag gaaagatata catttccata tagtgttgca aagatagctg
    15241 caatgataat tgaggaaaag tttgacttga aaatatgtga ccacgaaata ggatatatag
    15301 cattacattt tggaagttat tttgaaaaaa attcaagaaa agttctaaat gtaaataggg
    15361 tagctgttgt ttgtggaaca ggtcttggga ctgcacaact tattagaata aagataggaa
    15421 aaatacttgg agaaagtgta gaagtaaata ctttttctga tatagaagct aaagctaatt
    15481 tagatttatt aaagtattat gatttagtat ttacaacagt agatttcaaa acagacttag
    15541 atgttccaat ttttagagta aatgcgttat ttaatgaaga aagtataaag aaagagatag
    15601 aaaatgcaat acttttgaaa aatagtataa atcttaagtc tataaaaaag attgaaaaaa
    15661 atatcccttt tataggtaaa ttaattgaag aggataagtt ctttatattg aataagagta
    15721 cgtttatgga aaatttagaa gatatgttag aaaaattagt tcataaagga attattgata
    15781 tagagttcaa aaaaaaggta ttaaaaagag aaaagaaatc ttcaacagca ttagataatt
    15841 atatagcatt gcctcactca gttaatacta atggggaaaa tctttatctg gcatttggaa
    15901 tattagaaaa accagtgatt tgggatacaa aggaaattag aataataata ttgatgataa
    15961 ttccagataa gaatgtagat agtacagacc tgataataaa aagttatgaa gaagtacttg
    16021 aagtagggag agataaaaag atggtagaag aacttgctaa ggcaaaatca tttgatgaat
    16081 tttataaaat aattaccaag aggaggtaat aatatggacc cagtaatttt tattatagca
    16141 tcacttatta cagtgtattt attaaatatt tttcttggat acttacagct taaagatttt
    16201 aataaaaatt atattgaact aaaaagaaaa ggaagagtgg caattggcag aaaaaaagga
    16261 agaatttcat cgggtacaat tgtgttgata cttataaatg atgatggtgt gattgtagag
    16321 actagaaaaa tgcaaggtgt tacagtattg gcaagagtaa agtcatttga aggtttggta
    16381 ggaaagagct tagagtatat agaaaaatca gatttaactg tttacaataa actacttaaa
    16441 aaagcaatac tagatgcagt caaacagtac ataacatttg agaaaaataa atgtgaagat
    16501 acaaataatc tgagtactga tgaagagtgt aggatggaag tagtttaaaa aaatatattt
    16561 ataaggagga gttaatatga cgcaattttt tcaagtatta gcaagtggtg cagatagttt
    16621 tatgaattta tttagggcag gtgggcaaca atttgtaggt tttgtaacag atatagtacc
    16681 acttttagta gcattattag ttacaatgaa tgcaattatc aactttattg gtacagatag
    16741 agtcgagaga cttgcaaaaa aatgttctgc aaatatattt actagatatt tgatattacc
    16801 agtccttggt acatttgtat ttgcaaaccc aatgacacta tcattaggaa gattcttgcc
    16861 agaaaagttt aaacctagtt actttgcagc agcaagcttt tcatgccata caatgaatgg
    16921 attattccca catatcaatc caggtgaact atttatatat ctaggaattg caaatggtat
    16981 aacaactttg ggattctcaa cagcagattt agcagttaga tatttgttag tgggtatagt
    17041 tgcaaacttt attaaaggtg tagttactga ctatacaaca aaatttgtag agaaacaaca
    17101 aggaatagca ttaaattcag atataaagat tggataatta ctttaaggta taaataaatt
    17161 tttcaaataa aaagatagtg tatagaggag gataaattat atggcattta acaaagttaa
    17221 aatagtaaaa ggttctggag gatggggtgg accattgata atagaaccaa cagaaaagaa
    17281 gaataaggta gtatatgtga ctgggggagc aaagccagaa actgcagtaa aaatagctga
    17341 acttacaggg tgtgagttaa tagatggatt ttcacagggt gttaaagatg atgaaatcgc
    17401 atgtgtaata ataaattgtg gtggaacatt gagatgtggt atatatcctc aaaagaaaat
    17461 accgactata aatataatga aaacaggaaa aagtggacca ttagcaatgt ttataaaaga
    17521 agatatatat gtttcagggg taaaaccaac aaatgtagag cagttataat tgaggtagta
    17581 ggagggaaga aatatggctt atgatactaa aaagaagata agtgagcaga gtcaaggaat
    17641 tgttgcaaaa ataggtatag cactaggaaa tgtgacaagt actctttttc aagctggtag
    17701 ggatactata gatacattaa tacatactat actgcctttt atggctttcg ttgcagtcct
    17761 aataggtata ataaatcaat caggtatagg aaattgggta gccaatttac ttactccatt
    17821 aatcggaaat gttggaggtt tagttgtctt atcaataata tgttcatttc cgttgttgtc
    17881 tccgtttctt ggaccaggag ctgttatagc tcagatagtg ggagtattgg ttggtacaga
    17941 aataggaaaa ggaaatattc caccaagttt agcattacca gcattgtttg caataaactc
    18001 acaagcagct tgtgacttta taccagtagg tcttggtctt gcagaagctg aacctgatac
    18061 agttcaagta ggagttccgt cagttttata ttctagattt ttaacaggtg caccaactgt
    18121 tctattagca tggttagcaa gctttgggtt atataaatag aagaatactt tataaataat
    18181 tagagagagg ttcagttgat atggaattaa tatacagtac tcaaataaat aaaataggag
    18241 ataatgcaaa tgaattttta caacataata tgtttgtaac tttcaaagat aatgctcctc
    18301 aagagttaga aaattactgt tatatacatt ctgaaaataa tttagtaaaa gaaatactta
    18361 cggatgatgt gctatcaata aataatgttg attacaaaat tacttctgtt ggtgagttag
    18421 taaaccaaaa tctttcagaa ttaggtcata taacatttaa gtttacaggt gaaaaagatg
    18481 gagcaattgg aggaacctta tatcttgaag aaaaagaaat agcacctatt ggcgtaggta
    18541 ctatactaaa aataattaga aaataaaatt taaaacgaat ctaatcatat tataagtaaa
    18601 ttatagataa aagtcaattt aactaatcaa gttaactttt aatgtgataa aaaaggggaa
    18661 atgaaaatga gaaaagtggc tttagtcgtt ggaggaggaa gaagtttagg tgaatattta
    18721 tctaaacatt tagctaaagt aggttatgat gttgctattg cagatttaaa tgaagacaac
    18781 gcaaaaaaag tagctgaaga aataaaaact gaatttggtt gtaaatctgt aggatatagt
    18841 tgtaatgcca tagatgaaag acaggttata agtactgtca aagctattga aaatgatttt
    18901 gatagaatag atttattagt gtacaatgca ggagtggctg taagtaaaaa aataactgat
    18961 tttggataca aagattttaa atttattgta gacgtaaatt taaatgggta ctttctattt
    19021 gcaagagaag tatctaaagt catgatagca aaaggtattg agggtagaat aatacagata
    19081 aattcaaaat caggtagagt gggaagcaag cataattcag gatattcagc aggtaaattt
    19141 gctggagtag gacttactca aagtttagcg ctagatttgg cagaacataa gataactgta
    19201 aatgcactga tgctcggtaa tttacttgat tctgatatgt ttgaaagttt aattcctcaa
    19261 tatgcagtaa aattgggaat acctgaatca gaagtcaagc aagtttatat agataaagta
    19321 cctttaaaaa gagggtgtag atttatagat gttgcaaata tgcttacatt ttatgcttca
    19381 aaggaagctg aatactgcac tggtcaatct ataaatatta ctggtggaca agttatgtaa
    19441 ggtttttatg gagtgtctca agatgaactc tttagttcat gaggcacttt tttgtataaa
    19501 attaaatata ttttcagcat ttaaacaatg aaaaagaggt ttatctttat tttgagatag
    19561 cctcattttt gtaattaaaa aacatagtgt ttaagtaaac atataagatt gttagttttt
    19621 taaaagagaa ttttttaata atattatatt tatgaagtat ttttaaactt attttgataa
    19681 aatatagcta tgttttatat actgtagttt tgaacataga aagtttaata aattatagta
    19741 tatatgttaa tttttaataa ggtaagaaag tagaaagaag gatattttat ggatataata
    19801 aaaaaattaa gtcatgggtg tacattagat tgtcatgact gttgtaaatt caatgtttat
    19861 actaaaggaa ataatgtagt aaaaattgaa ggagataaaa atcatcctta tacaaaaggt
    19921 tttatatgca aaaaagggat ggcccattta gatagattaa atcataaaga tagaataaag
    19981 actcctatgc ttaaagttga tggagtatgg aaagagattt cttttgataa agctatagaa
    20041 ataatggcag aaaagcttac atactataaa gaaaagtata catcaaagtc tgtcatgcat
    20101 tatgaccaat atggaagtgg gtctgtgcta aaatacatag gagatatatt ttttaatttt
    20161 tatggaggtg ttagcagaca taaggggggt ccctgttgga gtgcagggat gcatgctcaa
    20221 aaatatgatt ttggagtagc taagagtcat gctatagaag atatgttaaa tagtaaaagt
    20281 atatttgttt ggggaaaaaa tccagcatat actacaattc atactatgca aataattaaa
    20341 aaagctaaag aaaaagggat aaagatagta gtgattgacc ccatatatac aaaaacagct
    20401 caaatagcag ataagtatgt acaagtaaat cctggaacag atggagcttt agctatagct
    20461 atggcaaaaa ttatagtaga agataaatta tatgatgaag aatatataaa ctcgtatgtt
    20521 attggttttg aagaatataa aaaatattta tcttcattgg aattaagttt tttaattgat
    20581 gaatgtggtg ttaaagagaa tgatataaga gagttagtgg atttatatac taacaaatat
    20641 tcaagtataa atgttggata tgggcttcaa aaatataaaa atggtggaaa cacaataaga
    20701 gcaatagatg ctttaggtgc tataactggt caaataggat ttagtggtgg aggggtaaac
    20761 tatgctaata aagtttatcc gagtgttata aattctgacc cttacaatag ccaatcatat
    20821 ggtgaagata gggagtttta tgtaagtaat atcagtaaat ttatagaaga atctttaaaa
    20881 aatacatcaa ataaagtaaa ttatgcatca gatgaacttg atatgacatc aaataaagta
    20941 aattatgtat cagatgaact tgatataaca tcaaataaaa cagattatat atcaaatgaa
    21001 ttgtataatt tatctaataa gtcaatcaaa ggtaatattc ctataaagat ggctgtaata
    21061 actaaaagta atatgctgaa tcaactgcca gatttagtag aattggagag ggtgttttca
    21121 aaaattgaat ttaaagtatg ttttgatatg tttataactg atacagctac tttatgtgac
    21181 atgtttatac cgtgtacaaa tacactagag agtgaagata taatttatag ttcaatgacc
    21241 aatccatata taacctataa tgaaagagct gtaaagccag cacataaatt gatggatgaa
    21301 tattacttct ttatggagct agctaaaaag atgggattaa atgattatcc ttttgtagaa
    21361 aagagaactt atttagaaaa agtgattgaa ccacttaagc gttttgacaa aaatctggat
    21421 atagaaaaac ttaaaaacaa ttactttact atacataacc ctgttgcttg ggaagataag
    21481 aagtttgaga ctccatctgg aaaatacgag ctttattcag aaagtataaa aaacttggga
    21541 ataagtccaa cacctgtata tataagcaat aaatataaag aaatagaaga taaaaatatt
    21601 tcttttagat tattaactaa tcatcatgca gatactttat ttagtcagca ttttatggac
    21661 aaaaaatcta tagctcaagc atatataaat cggagaatgg ctaaaaaagt aggtattgag
    21721 gacaaagata ttgtgatatt gaggtcaaaa aaagcaaaaa taaatgtaca aataaatata
    21781 gatgatggag taggtaatta tatagtaaaa atgtatgttg gttggtggaa gaaacatgga
    21841 aatcctaata gtttaacaga cactggtata tcagattttg ggggtcaagt aacatataat
    21901 gaaagtatgg tagaaataat acgacaaaac tagttaaatt tcattgaagg aataaaaata
    21961 taattataga attgattaaa agttactatt tttacaaaac tattgaagga gggatttttg
    22021 atggtaaatt attccttaga acataagaat ctatacatag aatttatgtg ctcagaacta
    22081 gaccaccatg tagccaatga aataagggaa gaaatagata acttattaag tgtaaatcaa
    22141 gtaaaaaatg ttgtatttaa ttttgaaaat attaatttta tggattcttc aggtataggc
    22201 gtcatcatag gtagatataa aaagatttct aatgaagggg gacgagtttc agtaattaat
    22261 ataagttcac gagttaagaa gatttttgat ttatctgggt taaataaaat tattggcatt
    22321 tatgatacgt atgaagaagc tctaagttct ttgtagggag gagtatgtga tgaataatat
    22381 tatggaagtt aaattttcgg caatatctga aaatgaaagt ttagcaagag ttatagtagc
    22441 atcctttgca gctaagttag acccaacagt agatgagtta gtagatataa aaactgctgt
    22501 ctctgaggct gttacgaatg ctataataca tggatatgaa gaagacagtt ctaagtttgt
    22561 tttcttaaga tgtgagatag aaggaaatac tataaagatt atagttgaag atgaagggta
    22621 tggaatagaa aatgtggaga aggcaatgga accactttat acatcaaaac cagaacttga
    22681 tagatcaggc atgggattca cagtaatgaa aagctttatg gacgatgtag aggtaagttc
    22741 tgtaaaagat aatgggacta gaattgaaat gactaaaaaa ataaatgtgc ctaaataaag
    22801 tccaaaagtg aggttttatt atggaagtaa ctgttgccag agaagaaaaa aaacctcttc
    22861 ttagtcatga agagactcta gaacttattg aaaaagttca aaatggagat gaagaggcaa
    22921 aagaaatatt aatatcaagc aatttaggtc tagttaggag cgttgtatct agatttttaa
    22981 atataggata tgatagagaa gatttatttc agttaggttc tataggctta ataaaatcaa
    23041 tatataaatt tgacccaaaa tttaatgtaa aattctctac ttatgcagta ccaatgattt
    23101 taggtgaaat aaagagatac ttaagagatg atggtatgat aaaagtatca aggtcgttaa
    23161 agcaaatagc tgtaaaggca aagatggaaa gtgaagcttt aactaaaaaa ttaggtagag
    23221 agccgagtat agaagaatta gctaaagcaa tagatgtaga aaaagaagat ttagtaatgg
    23281 ctatggaagc taatttcaat gttgagtatt tgcaaggagt tattcatgaa gaggaaggtt
    23341 ctccaatatg ccttattgat aaaataagca tgaaaggaga aagtgaagaa gaaaaagtag
    23401 tggataatat attgttaaaa gacatacttg gaagactgga taagagagag cgtcaaataa
    23461 tagttctcag atactttgaa gacatgactc aaagtgaaat aggagagatg ctcaatatat
    23521 cacaagttca agtatctagg atagagaaga aagtattgtc taagttaaaa gaatatatat
    23581 cgtgataata cttatgatat gtagaataac aaaatataat aaatatatta ctaaaataaa
    23641 atgtaataac tttttatttt aagtttttaa attattaaaa gatattaaaa taataaaaag
    23701 cattaaaaaa gtaaaaatat aaaaacaagg tgtctttatg gaaaaataga ttttttcttt
    23761 attaggcatc ttttttattt tttgaccaaa ctttagatag tcaaaataaa taataggttt
    23821 atttttttaa aattaacaaa taatacttta gagaggtgtt tagtatggat aaaaattata
    23881 aaaaatatgt agaccaaata agcccaaaac ctacatattt aaaaaactat acacttgcat
    23941 ttattgtagg tggaattatt tgtatgatag ggcaagcaat aaatgatttg tatatgaaag
    24001 ttggaggtct tgataaacta ggtgctagtt ctgcaacatc aataacatta atatttatag
    24061 gggcattttt aactggatta ggagtctacg acctaatagg aaaaagagct ggagctggtt
    24121 ctataattcc aataacaggt tttgctaact caatagtatc tccagcaatg gagtataaaa
    24181 gagaaggcta tgtattaggt gtaggtgcaa acttatttaa aattgcagga ccagttttag
    24241 tttatgggat aggttcttct attttatgtg gaattattta ttatattttt aagatgtttt
    24301 agatgatttt tatttaattt aaattttatt aattatgaag aaggtataaa atctgaaaat
    24361 agctactaaa gtaactaatt gaaaaataat tgtgcagatt taattaatat ttttaattaa
    24421 tattaaaaat ttgaatagta aaatgcaaaa ttaaaaaggt gtgaaaatat gaaaaataaa
    24481 agaattggaa aaagaacagt caagttagaa aataaaccaa ccataatatc aactggaact
    24541 atagtaggtc ctaaggaagg tgaaggacca ctaaaggact attttgatat gattatgact
    24601 gacgatttat atggtgaaaa gacttgggaa ttagctgaaa gtaaaatggt agagactgca
    24661 tctcaacaag ctatccaaaa ggcaggtaaa aaattgtcag atgtaaatta tatgctaggt
    24721 ggcgatttaa taaatcaaat agtgccagca tcatttgcag caagagaact ggctattcca
    24781 tttttaggta tatatggagc ttgttctaca atggcagaag gtctttgtat aggttctatg
    24841 cttatagatg gtggttttgc tgatttagta ctgtcaggta catcaagtca ctattgtaca
    24901 gcagaaagac aatttagatt cccacttgaa cttggaaatc aaaaaccaat gacagcccag
    24961 tggacagtta caggagcagg aagtgtatta ttagctccta atggagacgg tccaaaagta
    25021 aagtatgtta ctgttggtaa agtaatagat gagggtattg atgatggtaa taatatggga
    25081 ccagctatgg ctccagcagc aatagatact atctattctt actttgaaga tactaatgat
    25141 gatccaaata gctttgatat aattgctact ggagatttag gtactcttgg aaaacagata
    25201 gcagaagact ttttaaaaga aaagggtgta gatatatcaa aagtttacac tgactgtggt
    25261 atagagatgt ttaaccttaa agaacaagat gtccattgtg gtggaagtgg atgtggatgt
    25321 tcagctacag tatttgcagg atatatatat gataagttga gaaaaaaaga atttaacaaa
    25381 gtaatgcttg tatcaacagg agcactactt tcaccaacaa gtacactaca aaagcagaca
    25441 ataccatgtg ttgcacatgc agtagtaata gtaaatgagt aggaagtgat ataatatgtt
    25501 aatggactat gtaagagtat ttattgtagg tggaattata tgtttaatag cccaagtaat
    25561 gatggattat ttcaaaatgc aaactccata tgttatggta acgtatgtaa caactggtgt
    25621 agttttaact tttctaggac tttatgagcc attagttaag tttgcagcag caggtgcaac
    25681 agttcctata ataggatttg gatattcact tgctacagga gtaataaaat caattcaaag
    25741 tgatggtttt ttaggtattt ttttaggagg tacaactgct acagctggtg gaatagcagc
    25801 agctatattc tttggatata ttatgtcagt agtatttact ccaaaagcaa aaccataaat
    25861 ctttattaaa agaataataa gtttttgaaa taataaattt ttataaagca ggtggatatc
    25921 ttttagattc cacctatttt ttatataaag aagcgtttac ataattgaag ttgacaatta
    25981 tttacaacat agtgtagtat tatattatca aaataaaatg aagtgaagta ggggataaag
    26041 atggtaacta ttaaagatat tgcaaggaat ctaggtatca gttattcaac tgtttctagg
    26101 tgcttaaaca ataatcctaa tgtatctgaa aaaacaaaaa agaaagtggt agaagaggca
    26161 aatagactag ggttccattt taatgtaaat gcaagaaatt tagcaaaaaa agaaactaac
    26221 aggatagggg taatcttttc aaataatttt aatcatcaag atactagaaa gttttttagt
    26281 gatataatgg atagttctat aaattctatt gagactaata aatacgattt tataatacag
    26341 cctaataata acattagtgg tgatagtaat gtatataaaa tggtaaatgg acaaatggtt
    26401 gacggattag taattgtgtc tcaatcaata aaaaaagaag agtatgattt tttaaaagac
    26461 aataattttc cacatgtatt tatatatttt aaaccatctt ttataggaga agtagacaat
    26521 ttcttttggg acgataacgt gtatggaggt tatatagcta ccaagcattt aattgaccat
    26581 ggtcataaag atataataac agtaacttca gatgataaga gttcaaaaat gcatgaagat
    26641 agaaccaagg gatatttgaa tgctatggaa gaggcaaatt taaagacaga agtcattaaa
    26701 tctaaaatgg attttgaatc tcaagttgaa tttttagaaa aatacattga taaaataaaa
    26761 aaagcttcag ctatatttgt acaacaagat gtaccagcga tttctataat acaagagtta
    26821 aaaactactt atggtataaa tgtaccagaa gatatttcca taatagggta taataatatt
    26881 gaattaatat catattttag gtcgcattta tcaacaatag atgacccaag agagcaagtt
    26941 ataaaaaatg gagtagatag tttagtaaat ataataaata aaaagagtac agaacacatt
    27001 ccaagaaaat tatatccaag gttaataata cgaaatagcg ttaaaagaat aaagtagtaa
    27061 gcttttaagt atcaaaagtt tattaaaaat attatagatt atgtgaagtt ttttaacaaa
    27121 taatataaat aaaaattaaa aggagtaggt gtatataagt acattgtact cctttattta
    27181 ttgagatagt ttttataata tgaatgaata attttattca attatttgaa aatccgttat
    27241 tttaacaata taaattaata aattatttgt attttatatc atgaatctat aatatttttt
    27301 tgattcataa ctaaaagtat ataaaaatga tgaataaata tatattatac attatcaatg
    27361 ataggttata taataaaatc actaacaatt gtattataag aaaattataa aaattacaag
    27421 gaggtataga aatgaaagaa aaagcaggga ttagaaatgc cataatagca gcctttataa
    27481 tcacaatatt ggcagaatta attggaccta tttcatttaa agttatggga attaatgtaa
    27541 ctttacttag tatactatgg gctatattca taggaatggc tgtttctcct catttattag
    27601 ggagagttat accagcctta aaaaagttta taggggataa tgaaataaat gtatctccat
    27661 atttattatc tttgacacta tatccattag ggataatgtt tggaattaat gcaggaccta
    27721 aagttggtat attacttcaa gcaggaccag cacttttatt acaagaattt ggtcatatgg
    27781 gtacaatgtt gatagcatta cctgttggag tagcattagg tcttggaaga agtgcattag
    27841 gtggtacttt ttcattatgt cgtgacacag cactaggaat tattggagat aagtatggat
    27901 taaactcacc agaaggtata ggaacactag gaacttacat aagtggtagt atatttggaa
    27961 cattattatt ttcattttta gcaccagtgg gtgtactttt aggatttcat ccatatgctt
    28021 tagcaatggc atcaggaatg ggtagtggtt caatgatggg agctgcaaca gcatcattaa
    28081 tgaatacggt tccacaaatg tcagagcaga ttttagcata ttcagctact agtggattga
    28141 ttacagctgt tactggaata tatatagaat tattcttatc tttaccagta gccaactact
    28201 attatagcaa agtagctcca gttattgaaa gatttagagg aagaaaaaca agaagaacaa
    28261 gtaataaatt gtaaaggagg atatatatat ggaaaaaact tttaagacta ttatggagca
    28321 gataaaaata gtattgttta tatatattat tatttgcttt ggacaaatga tagcacttaa
    28381 gactcaggct caagatttgt tgattggaag tgtatctgga tttttgttgg tgataattgc
    28441 tattataata aagaattttg ttaaaaaacc taatttacca ggttttgcat gggctacatt
    28501 agttgcattc gttttatcgc ttccaatatc tccagtgggg gatatcatag caacaaatgt
    28561 agggaaaata aattttatgt ctacagtaac accattatta gcttttgcag gaatctctgt
    28621 aggtaaccaa ttagatatat taaagacttt gagttggaag ttagtagtta tatcatttat
    28681 agttatgaca tctacttact ttggttctgc ttttatatct caaacagttt taagattaaa
    28741 tggaatgctt taaggaggta gtaaatatga atgaattaaa agcaaaaatt aaagaggaaa
    28801 taaagttatt atctgaagag aaaaagacat catttgaaaa agtttctgac tatttatttt
    28861 caaatccaga attagcattt gaggagtata agtcacaaaa agcattatgt gatttgttag
    28921 aagaaaatga atttaatgta actaaaggtg taggaggatt agaaacatct tttgaagctg
    28981 tgtattcaaa tggaactaat gggaaaacag ttgctttttt agctgaatat gatgcacttc
    29041 caggaatggg acatgcatgt gggcacaata tcatagggac aagttctgtt ggtgcaggta
    29101 tcatattaaa agaaatcatg aaaaaacata atatagaagg gactgtaaag gtttttggaa
    29161 cacctgcaga agaaagagta ggtggaaaaa taactatgat taaagaaggt gtatttaata
    29221 atgtagatgc tgcattaatt ttacatccaa gtgatgcttc aatgcctgat gatatatcat
    29281 ttgctcaagt taatttaaaa tttgatttta ctggtaaggc atcacatgct gctgcttttc
    29341 cttgggaagg gaaaagtgcc ttaagtggag taatagcact atttaacagt gtaaatagca
    29401 tgagattaca tcttaaagat tatgcaagag tacatggaat tataactgat ggaggtagca
    29461 tacataatat aattcccgaa aaatctacag ctatatttaa tgtaagagct ttaagcatag
    29521 aatatttaaa tgagatttgt gaaatgctta aaaattgtgc taaaggagct gcaatttcta
    29581 ctggaactaa tgtagaaata gttcaattag atgaaatata caaagagatt aagaatgatt
    29641 ctgaattagt gaatatagtt agacaaaatt ttgaagtttt gggtgaagac tatgttgaaa
    29701 gagatttaag tcaaggtata ggttcaactg atacaggaaa tttaactcat gagatacctg
    29761 caatacaagc atatataaaa ttaaaagaaa atactgcaac tcatacagat gaatttgctg
    29821 ttgcagctgg tggtgaagaa ggcaaagtag cacttataaa agcaattaag gtgctagcaa
    29881 tgtgtggagt agatattttg tatagtaaat aatatataat tttaaaatat attaagaaag
    29941 gaaatcagat tagacatgat attaaaacaa gtaatagagg tttatgacat tttagataaa
    30001 gcaaatgcta atggggaaga agtaaaaact tacttacaag gttatggtga agtagatgta
    30061 actgtaaaag aattgtcttc aagtaaaggc tcaacagatt tagtaaagct tacaattcct
    30121 gggaaaaatg gaaaattaaa aggtggagat gctcctactc ttggcatttt aggtagacta
    30181 ggagggattg gagcaagacc agaagttata ggttttgttt cagatggtga tggagcattg
    30241 gtagcaattg cagtggctgc taaacttttg gatatgcaac gaaaagggga tatattagat
    30301 ggtgatgttg taatttcaac ccatatttgc ccagatgctc caactaaaga acactatcct
    30361 actcctttta tggattctcc aattgatatg atgactatga atgaaaatga agttgatagt
    30421 agttgtgatg caatactttc tatagatact actaaaggaa atagagtaat caatactaga
    30481 ggatttgcaa tatcgccaac tgttaaagaa ggctacatat taaaaactag tgataacctt
    30541 ttagatatta tgcagactgt aacagggaaa tctccatttg tattcccttt gtctattcaa
    30601 gatataacac catatggaaa taatctgtat cacttaaata gtattttaca accagcagta
    30661 gctacagatg caccaatagt aggagtagca attacaacag agatgcctgt tgctggatgt
    30721 gctacaggtg caactaattt tagtgattta gattcagctg ggagatttgc aattgaagtt
    30781 gccaagctat ttggtagaaa taagtgtgat ttctatgata aagaagagtg ggaaatgctt
    30841 attaagagat atggcaaatt aaatagattt caaacatttg gtatacagta attagaaaaa
    30901 tattaagttt atataatttg tgatataact atttaagaat atataaacaa ttaggaataa
    30961 aagtaagaat aaagcactta gttaaaaact ttaaaaataa aatatttatt tgtttatata
    31021 aaaaaggagg attctggtta ttgggattct cttttttatg aatacaaata atatattgta
    31081 attataaaaa aaggagcgtt tcaaagtgat ttttttaatc accttgagac aactccttat
    31141 atttttattt aaattctatt ttttattaag ttgctggagt tccaccacca tcaggaggag
    31201 tagtagagcc accaccatta tttccaccac catcaggagg agtagtagag ccaccaccat
    31261 tgtttccgcc attatcagga ggagtagtag agccaccacc attatttccg ccattatcag
    31321 gaggagtagt agagccacca ccattgtttc cgccattatc aggaggtgta gaaccgccac
    31381 cattatcacc tgtgttatta ttgttattat tattttcttc tggttggtta ttgtctggtt
    31441 tttttgtatc ttcagatgat ggttgagaac ttactttagt aggagcagta ccttcaataa
    31501 atgctgcttt agagccagaa gattgctttc ctccatcctc taaattaatt tttgtaaaat
    31561 atacattttt aggaacttca aattcagtaa ccgttaaatt agcatgtatt ttttccataa
    31621 ttttttccca tagttttgca gtactagtac ttccatgtgg tacttctcta cgttttatag
    31681 tgttaccaga atcatctttt ctaccagcat catctccaat ataagttgca ccaacataat
    31741 aaggagtgta accgacaaac caagcatcat atgcactatt tgtagtacct gttttacctg
    31801 ctacaggcat tccctttgga agtgtagcaa caccaccagt accttcagta attacgcttt
    31861 ctaacatatc tgtaacaaca taagctactt cagggtctac aactttatgt tcttcaggag
    31921 catttttaac taataattga ccatcaaagg tagttatagt agtaaaaata gaaggttcta
    31981 cataaatacc gtgatttgcc aatgtaccat aagcagcagc catttgaagt ggagtaatac
    32041 cattcgccat accacctagt gtcaatgatg ggaattttct atcacttgct tcagatgaac
    32101 ctgagtgatt attctttaaa gttgttatac caaagttctt taagtaatcc atcattatat
    32161 ctacacattc atcataagag tctccaagca tttcagcagt tttgacagct atcgtgtttg
    32221 aagatttagc aagtgcttta cgtaaactca tagaaccatg accagcagta gtagttcttg
    32281 gattccattt attattttct tcaaacttat atcctcctcg agaatcactt agagcagttg
    32341 cttgtgttat ttttagagta tcaatagctg gcgtatatat tgctaaaggt tttatagaag
    32401 aacctggctg atgagggtta gtagcacgat ttaaagtttt tctaccactt atatttcttc
    32461 ctccagctag tgctcttatt tcaccatttt tataatctaa gattaccatt gcagcttgcg
    32521 gttggctaac tccatcagga ccgaccatat gtcctgggaa attgctattt ctatcaaatt
    32581 cttcttctaa agcatcttgc attttagggt ctatagttgt gtttacaatt agaccaccat
    32641 tgtagaataa gttttgagct tcatcatttg tatgtccttg ttccattaaa gcatttataa
    32701 cttcactttc gataaggtct tctacagatg aagaaacttt atctgatgat tgaggcaatt
    32761 ttatttctat tttagctttg attgcttcat catattcact ttgttttata tatttcaatt
    32821 ctaacatttt ctttaaaaca atttcttgtc tttttttagc ttcaggatta cttacagcct
    32881 ttctaacaac taatgtacct gcttttaatt gtctataagt atcattagat ataagctccc
    32941 aagattttat tttttcaatc atatcaaagt ccacttgagt agggtcatct aaatcatcat
    33001 cagttgtgtt aacaaaaaat aataatttat tctctaaatc ctccttagtt tcatttccct
    33061 ctaacttaga agttttatag gctgaaaatc ttgatggatt tttagttgaa ccagcaagaa
    33121 gtgctgactc tgctagagta aggtcagctg cagacttatc aaaataacca cgtgcaccag
    33181 cctcagcacc tgctagacct ctaccaacga agaagttatt taaataagtt tctagtattt
    33241 tatctttact tactgtttta ctcatctcat gtgcatagta aatatccttt attttacgag
    33301 gtatagtttg ctgttcagtt gttaacagca ttttggatac ctgcatagga atagtactac
    33361 caccttgctt agtacctgta agggtcttta atactgacct aaataaacct ttaatatcga
    33421 cacccttatg ctcataaaaa cgctcatctt ctattgcaat tacagcatgt tgaagataag
    33481 gggaaatctt atctaatgga acgggtgtct ttttatttac acttggagct gtagataatg
    33541 tttttccatt agcgtattta atagtagttg tttggttcgt ctgtttatct aaaacagctt
    33601 ctgtaactgg agttacatct cttagtgacg caaatactag accagcagta cctgctgtac
    33661 caacaactag taaaactaaa aatactatcc caaatactct tagtttttta aatttatcgc
    33721 tttttttaga ttttttcttg ttttttgttg aacgagtctt gttagctgaa gttctattaa
    33781 ttggtttatt tgtattacca gatgagctaa ctttttttct cctgatttta tttccatttt
    33841 tatcattatc gttattcata agattttaac ctccttactt aatgcaatat tataacacaa
    33901 ataggagtag ttttgtaatt aatagaaaaa atgaatttgc tataatattc tgtacattgt
    33961 atatgtataa acgtaatata ttaaaaagtc tatattttta ttttatttat ttttgacaaa
    34021 tattataaaa attatgccaa agctacatat aaataaatag gaggggataa ttttgaatag
    34081 aatagtagat agaaaaacaa aaaatgaatt tagaaaaatc atagctattt ttttagtaat
    34141 tcttttcttg tctgtattta taggcagttt tatatatata gataaaactt taagaccgac
    34201 aataacagtt ttagcagaga ctaaagctct tgaactagca aataggtcga taaataaagc
    34261 tgttgctgag atggtagaag gaaaaataaa ttatgaagat ttaatggata tacaacttga
    34321 taataatggt aaaataacta tgatacaagc aaacactata atgatgaatg aaattgcatc
    34381 tgcaatagct ttagaaatac aagatgaatt aaaaaaggat aagacagcaa gttcttacat
    34441 acctatagga acagcattag gaagtcctat attagctaaa tacggtccta aacttgaagt
    34501 atctattgaa cctataggaa cagtatcagt aaactttaaa acggaatttg agtcttcagg
    34561 tataaatcaa actagacata gaatatattt agaagctcaa acacaagtta aagtagtaat
    34621 accacttata acttcaacaa aacaaattaa agctcaaata cctatttgtg aaactataat
    34681 agtaggtgat gttccagaaa gttatgtaaa tattccagaa aaaaatctag gaaatgtttt
    34741 acctaacact ggaaagaata ccaacaagta atgtaaagtt gtatattttt aaataaattc
    34801 aaaataatag tttataaata aaatttttgg aaataatatt aatataattt taataaaaat
    34861 ttatatttta tactatgtaa aatatctaat atatttggtc tgtaggttaa ataaaagtac
    34921 ctttagacca aatatattat taataactta ataacatctt aaaacttatt tatttatatt
    34981 atttacaaca tccatttaat aaatacacca taacctacag ctgggtcgtt ttcaattgca
    35041 tgtgacactg ctccgattat tttattatct tgaactattg gagtaccact cataccttgt
    35101 acaataccac cagtttgagc taaaagcttt ttatctgtaa ttttaatttt aaaactttta
    35161 ctttctggat gtttttggtt ttctatatct ataatttcaa tattatattt tttacactta
    35221 ttaaagttat cttgtaaaat tatttgagct tttcctaatt taacttcatc taaagatgct
    35281 actttatatt tttttaactt ggaaatatca aagttattaa tttgacctct tattccaaaa
    35341 tcagtatttt ctgtaaagct accaataata ttttctcgtt ttgcatttat acatccaaca
    35401 ctacctttat aagatttttc tatattaagg tgcttagttg tagaaattga acctgtttta
    35461 ataggtattt ttcttgcatt accaacactt attggatgac ctacagctcc aaactctgat
    35521 gtatctggat tgatatacgt taaagtagca aatccagaaa gtaaattgtt aaaactaatt
    35581 ttttctaata tgtgtttggt agttttcatt gttataagtt gtccacctct atttaataaa
    35641 atagatactt gtttttcttc tggtaaagca tttaaggtat tggcaaagtc actatatcca
    35701 tcaacttcag cattatttac ctttactata gcatcaccca atctaaatgg agatgcttct
    35761 ccaggatttc taactatgat attttttaat tctgcgtcaa tttgaagtac gtttccaatt
    35821 ggtattaaat attcaggttc atttttttgt aaattttgtg cataaattaa attatttgag
    35881 aaaaaatata ataaaaataa aaatgttaaa acaattgtaa attttgactt agctaagttg
    35941 gtttttttac ttaaagtatt atttttaaaa tgaaaatttt taagttgcat aaaacacctc
    36001 tttcttatta aattatttta ataatagaat tgaagttttc ttgctgcttc tatattatgt
    36061 tgtgcaagaa tcatgttttg atgcttggaa aactagctca ataacacctt agttttcata
    36121 aaaataaata aaataaatag tgtatatgat aaaataaata catattcata taaataaaaa
    36181 taaacaataa ctgtctagca taagaaagga gcaaaaaatg aaaaaatata gattgttagt
    36241 tacttgtata attgccatgg gaatcataat tataggaaca tcaaatccag ttagcaattt
    36301 ttacaagact acaaatttga ttagttcagg aaatatcaca aatgaaaaag cagataaaga
    36361 tgaaaattca aacaaaaata ataaagataa aaatgaagac aaatctaatt ctaaaagtaa
    36421 taaagataag tcatcagagg acaaatcgtc agataataaa aatgaaattc aaaaaaataa
    36481 aaaactttta atttgtatag acccagggca tcaaggaaaa ggagatagca atttagaacc
    36541 agtagctcca ggttcttcct ctaaaaaagc gagagtatct tcaggaacag agggtattgc
    36601 tacaaaaaag ccagaatatg ttttaaactt agaagcatct cttgttttaa agagtatatt
    36661 agaatctaaa ggttataatg taataatgac tagagagaca catgatgtaa atataagtaa
    36721 ttcagaaaga gcaatacttg ctaatgacaa aaaagcagat atggttgtaa gaatacatgc
    36781 agatagttta aataattctt caaaaactgg agcatctata ttgattcctg aaaaagatgg
    36841 aaaatataca gctcctatat atgaagaaag taataaatgt gctgaattta tcaaacagaa
    36901 tatggaacaa tcaggtatac aaatcaatgg aatcgttcaa agaggtgatt tgactggatt
    36961 caactggtca aaagtaccag ctgtattagt agaaatggga tttatgagta actataatga
    37021 agaccaaatg atgtcaaatc cagactacca aagaaaaatg atgcagtgta tagctgatgg
    37081 attggatgcg tattttaaat aagatatgaa tagagaaaaa gttaggttgg tattatttgc
    37141 ctaattttta tctctatttt ttattgtaca taacacaaag aagaagttta ttttaggtta
    37201 aattgtcgta aatataacta aaaatattgg gaatacttga tttaagttta aaaagaatat
    37261 attatagtat agaatgtgta aaattttttt gagaggtgtt gaaatgctag tagtagaaaa
    37321 tgtgagtcat ggatttggtg cgagaacaat attagaaaat gtatccttta gacttagaaa
    37381 aggtgaacat attgcactag ttggtgctaa tggagaagga aaatcgagtt ttttaaatat
    37441 aataacaaag aagcttatgc cagatgctgg aaatataaaa tggtcttcaa gagctacagt
    37501 aggttactta gaccaacata cggtattaag caagggaaaa actataagag aagtgcttag
    37561 agaggctttt aagcatatgt ttgacttaga gcaagaaatg attgctatgt atgacaaaat
    37621 gggagaagct agtgatgatg aaatgagtaa gcttcttgaa gaaacagcag agatacaaac
    37681 tatacttgaa aatagtggtt tttatatgat agatgcaaag atacaagaag ttgcaaatgg
    37741 tcttggtctt ggagaaattg gtcttgataa agatgtaact gacttaagtg gagggcaaag
    37801 aacaaaagta cttcttacta aacttctact tgaaaatcca actattctta tattggatga
    37861 gcctacaaac tatttagacg aagagcatat aacatggctt actaagtacc ttcaagagta
    37921 tgagaatagt tttgtcttag tttctcatga tattgaattt ataaataata catgtaatgt
    37981 aatatatcat atggaaaatg gagagttaaa tagatataaa ggaaattatg atgaatttgt
    38041 aagacttaat gatataaaga aacgtcaaga agaacaagct tatgataaac aagttgaaga
    38101 aagaaaaaga ctagaggatt ttgtagctag aaataaagct agagtagcaa ctagaggaat
    38161 ggctaacagt aggcaaaagc aacttgataa gatggaaata ttagaaagac caaaagaaaa
    38221 aataaaacct acttttgctt ttaaagatgc tagagcagct agtaaaataa tttttgaaac
    38281 agaaaattta gttttagggt atgatgaagc attgacaaaa ccacttaatt tccatttaga
    38341 aagaggaaaa aagattgcct taaaaggaat gaatggtatt ggaaaatcta ccctattaaa
    38401 aactttactt ggaataataa aaccatttga aggaaatgtt aaattaggtg actatttgga
    38461 agttggatat tttgaacaag agagttcaag agaaaatagt aatacaccta tggatgaagt
    38521 ttggagtgaa tttccagggc ttacaaactt tgaagttaga caggctcttg caaaatgtgg
    38581 acttacaaat gaacatataa cgagtcaaat gagagtatta agtggtggag aagctgctaa
    38641 ggttagactt tgcaaagtaa tgttaaaaaa tataaatttc ttagtattag atgagcctac
    38701 aaatcattta gatgttgagg caaaagatga attgaagaag gctatcaaag agtttaaggg
    38761 aacagttctt ttagtatgtc atgagccaga attttattca gaaattgttg atgatgtatg
    38821 gaatatagaa gattttacaa ctaaaatcgt gtagtgattt aacttattgc tggggggatt
    38881 tcatgaaaaa gtttctaaat gtactttttt caatttgtat tagtattgtt ataatagtag
    38941 gtgttattaa ttttactgtt ggatttaaac aactttatta ttttgacatt gattacttaa
    39001 atatatcaga gttatctggt ttatctaaag atgatataaa attgaactac gattatctaa
    39061 ttgattataa cttaaataag aatgtgtctg agttcaaatt accaacatta aaatcttctc
    39121 cacaagggaa gatacatttt gaagaagtca ggaatatatt tcaaaatata aataaattag
    39181 ctaaattatt attggtagtt tctttagtag gaattatatt gagtgtaaaa aataaaaata
    39241 taaaaatctt aaaaactaca tcaataacac ttataattat gccattatta ttaacagttc
    39301 caattttatt aaattttgaa aagtcattta ttatttttca taaattatta tttagaaatg
    39361 attattggat atttaatccc gatttagacc cagttataaa tatattgcca gaggaatttt
    39421 tttttcactc tggaatgatg attttaatat taattttgtt agtaagtata gtactgtttg
    39481 taatgtataa attatgtaaa tctttatcaa taaaaatatt tcaatgttaa atagagggat
    39541 atttttattt ccaaaataag ataataaaaa aggattagat taaaagttat acaataaaaa
    39601 tagctgtgca ataatattta gactatgaaa gtagttaaaa aatatttatg cacagctatt
    39661 tataatagaa tttacttttt actagtgatt ttaactaaat cttgaaattt actcataatg
    39721 taattgtaat tatctttttt atgaggtaat atacaactac tgcaattttt gataccttta
    39781 tctgtatacc taaagtttcc accacagttt tctcctaaag catacaaagg acaatagcaa
    39841 aatagacagt taaactcttc tggtttatta gttttatgac aagggaaaaa ttcgcaatct
    39901 ttgtgattaa aaaacttata attttcgccc atattttcct cctaattaaa taaaatttaa
    39961 attttttata ctatataaga ttttggtgat aatataatta tactaaataa ttttatgaat
    40021 agtcgataat atagtattat taatcatagt attaatggta taattagtca acagaaaaat
    40081 aatgtaaaaa taatgtaagt gtattttgta attagaatat gttttataac aaaaaatgag
    40141 gtgattaagt gaaagaaatt caagaaaaag cacttcttgt aggtctgaat ttgactacaa
    40201 tagtgaaaaa aaatgatgat atagacacta atgaatctat ggaagaatta aaagaactaa
    40261 caaaagctgc tggggcagaa gttgtaggta gcttaattca aaataaacac tctgtagatg
    40321 cagcttatta tataggaaaa ggtaaagtag aagaaataag agcctatagt gactctttag
    40381 atgctacttt agtaattttt aatgatgaat tatctggtgc tcaaatcaga aatatagaga
    40441 atgttgttgg aagaaaagta atagatagaa ctactttaat tttagatata tttgctcaaa
    40501 gggcacttag caaagaaggt aaattacaag ttgaattagc acaattaaaa tatagattgc
    40561 cacgacttta tggaatgggt ggtgagatga gtagaacagg tgcagggatt ggtactagag
    40621 gtcctggaga acaaaaacta gaaatagata agagacatat acttaataaa gcagcagata
    40681 taagacgtga acttaaagaa gtaaaaaaga atagagagac acagagagtt aagcgtttaa
    40741 agtcaaatat accgattgta gcacttgttg ggtatacaaa tgcaggaaaa tctaccctgt
    40801 tgaacgaatt aataaagaca cacaaggatt atgaacaaga aaaagaagtt tttgtaaaag
    40861 atatgctttt tgcaacttta gatgtaactt tgagaaaggc tcttttgccg aataaaaaag
    40921 aatttttagt agtagatact gttggatttg taagtaaact tccccatgat ttagtagaag
    40981 cgtttaaggc aacattggaa gaagtacagt atgcaaattt aatcttacat gtaattgatg
    41041 caacaaatac tagttatgaa ttgcaaaaaa gtacgactga aggtgtatta aaagaacttg
    41101 gtgtaaatga taaaaaacat atacttgtat ataataaagt ggacaagcta gaattggata
    41161 tataccctaa aagtcaagaa gatattgtgt atatttctgc aaaacaaggc ataaatatgg
    41221 ataagttatt aaatatgata gaaattgctt taatggaaaa tacttattca gtaagtttga
    41281 tgttacctta tgagagaggt gatatattta gtagaataaa agataaatat aatgtggaga
    41341 attttgagta tggggaaagt ggtataacgc tagatgcaga tttagatgaa gaagatttta
    41401 atatctatag agagtacata ctagaaaaat aggttgaata tggatataaa ctgggaaaat
    41461 atagataatc ttgaagatta ttttataacc tatcttcttt ataaagaatc taaaacagta
    41521 tctcaaatta gtaaaattag aaatatttca agtactgaag caagtgagca acttatacaa
    41581 gcaaagttaa aaataaagga aatgcaaaaa gatgattttg aggcatctaa ggatattttg
    41641 gataaatttc tagaactaga taaaattaag agacttgatt ttatggatag cttagatgac
    41701 gaaaaaatgg tatactttaa gagaaaggtt ttcaaaagaa tccttgtaga aaaaaatgct
    41761 gaagatttaa ttgttttaat ttgggcgaca ggtgagctaa aagatgatag gtttttgaaa
    41821 ttgcttcatc agctcacaaa ccacagacac tcagatatta gaagaataac ttattcagca
    41881 atcagaaaga ttgaatcacc aagtagtaga gaagtactgc aaaaaggtct ctacgacaaa
    41941 aatgcacaga ctaggcagta ctgtgcaaaa gctctttcaa aattgggaga tgaaaacagt
    42001 ttaaagattt tacagcagtt gaaagacaag aataagaatt ttgaaaaaga atatgtgctt
    42061 agagcttatg acgaagccat taagtcattg gaaaatgcaa aaaatttgaa aaagtaattt
    42121 tttattaaag caatttgttt acttaatgat gtatttctaa agtttaacaa ggtaataaat
    42181 aaattaatgg gaggggtttc aaatgatagt aagacgttgt gcaggtggag tagtgtttta
    42241 tgctaataaa gtacttattg taaaaaatga taggggtgaa tggacacttc caaaaggaaa
    42301 gatactagga gggggacttc catatgagag tgctgttcaa agagttaaag tagaaactgg
    42361 catagatgct aaaatgatag atgtggctgg cgatactatg tatgaatttt tctcaagaag
    42421 tagacaacaa gaagtttgta atgcaataat gtggtatgtt atggaagctt gtaacactga
    42481 ttgtgtactt gctcctgaat ttcaagaagg tggattttat aaagtaaagg atgctttaga
    42541 aatgttatca catcataaag agcaagcttt agtagaagta tcttataaaa agtttaagga
    42601 attaaagaaa ttagtttcag agggcgatga tgttccagca aattaattgt gaatttagag
    42661 gattctgagg aagggatagc cccttccttt tttaattgaa gcagttttaa gcgtaaatta
    42721 tatagtctct ttaaactatg atttatcaat ttagagattt agtagtttat atttaaaatc
    42781 agtaagatat atttaaaata aaaattaaaa agtatacaat tttattatat aattgtctta
    42841 tgatgttgat taaagaatta ttaaaagtcc atttattttt aaatagaata attttataaa
    42901 tatatatttg atgtgtatat tagaaaatga ttaaaatagg aggaaataca atgagcaatt
    42961 acaggacatt acatgaattt ggaacggatg aaataacgat tgaaaagtct gtttttattg
    43021 gatatgctaa gcctataaag agtgaagaag aagcattaga gtttataaat gaaataaaga
    43081 aaaagcataa agatgcaact cacaatgtgt gggcttatac tgtaggtaaa aatatgaata
    43141 tacaaagata tagtgatgat ggagaaccac aaggaacagc tgggatacct acattagagg
    43201 ttataaaaaa agaagatttg agagatgtag cggttgttgt tactaggtat tttggaggaa
    43261 caaaattagg tgcaggtggt ctagttagag cttatacaaa aggtgctaaa ctgggacttg
    43321 aagcaggtaa gataatttat aaggtaatgt atcaagaagt taaggttaag atagattata
    43381 ctcaacttgg aaaagtgcaa aatgagttaa tgaatttggg gtattttata aaagatactg
    43441 tatatgagga taatgttgaa atagtagtat attcaagatt agaagatgta gagaaattat
    43501 cagaaaaaat gattgatata acaagtggaa caggaaaaat agttttagga gaggaatttt
    43561 atttgtctga acaaaatgga gaaattttaa tataatctaa aaggttatta gaatagttaa
    43621 tacctcaaat agccaattag tatttttaag tgaaaagcca ttaaattgat ttaatctaaa
    43681 tcaatttaat ggctttttat cggattttgc acagaatcct ttttttactt caaataaacc
    43741 gactaaaagt aaaaatatcc caaatatttt ttttaatata tctgaagaca gataattagc
    43801 taatagtgaa ccaaatacag ctcctaaaac cccaaacaca gctataggta taaccaattt
    43861 aaaaattaca tttttatttt ttatatgtat agcaagtgct ataagtgtca tagggataga
    43921 tgaaagtaaa tttacgcttt gtgctatttt agtgtctatg ccagcaagta aaacgagtgc
    43981 aggtataagg attgttcctc cacccattcc cattcctcca ataattcctg caaaaaatcc
    44041 aattagagca aataacatta aaacaccatc cttaatgctg caattatcat aattattcca
    44101 aaagaaattc taagaaactt tccagtaacc ttatttagta atttagctcc tataatacca
    44161 ccaagaatac ttccaactgc aactttaatt gttaagttaa catcataagt acctttagat
    44221 acatataaaa cagaacttgc tgtcgttaag aatattatta tagaaagagc agttgcatga
    44281 gatttatgtt cttctacctt aacgatgtca tttaatattg gaactaaaag agtacctcct
    44341 ccagaaccaa aaactccatt tataaatcct gtaaaaactc caattatcgt attttttaag
    44401 ttaaaatcaa agtatttttt ctttaaatca tcagtttttt tcataaaaat caccttctga
    44461 aatagtttta ccaaaatagg caaattatat ttatataaaa taagattaaa tataatcttt
    44521 catgtttgtt taattttgca taaaaaaaaa catattaaaa caacatatta atatatggta
    44581 taatatatta aaacaaagta gcaaatttga gaggagataa caatgtcaaa tataaaaata
    44641 caaatagaca aaactgtaga atggcttata aataaggtta atgaggcaaa tgcaaaagga
    44701 ttaattgttg gtgtatctgg aggaattgat tcggcagtag ttgctaattt aattaaaaag
    44761 gcatttccag aaaactctat gggagttata atgagcataa aaagtaatcc tcaagataga
    44821 gaagatgcac ttaaggttat agagggatgt gatatagaat accttgattt agaccttata
    44881 gaaccacaaa gtgctatatt agacatggta gtaggaaatt taaaagataa acatttatat
    44941 agagaagaat atttaaagat gacagatgca aacttaagag caagagtaag aatgagtaca
    45001 atttatacaa ttgctaacaa tctaggatat ctggttgttg gtacagacaa tgctgcagaa
    45061 atacacacag gatattttac taaatttggt gatggtggag ttgatatttt acctattgca
    45121 aatttaacta aaggagaggt gtatgaatgg gcaaaagagc ttggtgttca tgaagattta
    45181 ataaacaaag ctccttcagc aggcctttgg gaaggccaaa cagatgaaga tgaaatggga
    45241 actacttaca atatgataga tgctgtgtta gaaggtagat tggatgaagt tcctaaaaga
    45301 gaccaagaga taattgaaag acttcataga ttaagtgaac acaagagaaa aacgcctgca
    45361 caacctccta agttctaatt tactatttat aagatttgtg ataaaattta caagtgatga
    45421 aaattagaat aattaattgt acgtattaag gagtggaaat atgggacgta taggtaatat
    45481 aattaataga aaaggtaaac aagatgctca aagagcaaag atatttacta aacatgctag
    45541 agcaatagca gttgcagcta aagaaggtgg agcagaccca gagtacaatg cagcgttaaa
    45601 aacagctata gaaaaagcta aggcagataa tatgccaaat gataatatag atagagctat
    45661 cgctaaaggt gctggagcag gtgctggaga agactatgaa actatagttt atgaaggata
    45721 tggacctggt ggagttgctg ttatagtaga aactttaact gacaacaaaa acagaactgc
    45781 tggtaacgta agatactatt ttgacaaaaa cggaggaaac ttaggaacta gtggatgtgt
    45841 gtcttttatg tttgataaaa aaggacaaat attagttggt ttaggagatg gagtttcaga
    45901 agaagaattg atggatgttg cattagaagc aggagctgaa gatttcataa cagaagaaga
    45961 tggttatgaa ataataacta caccagaaga tttttctagt gttcgtgatg agttaaaagc
    46021 taaaggatat gagtttatat ctgctgatgt gaagatgata cctcaaacta caactgtatt
    46081 gactgaagaa tctcatttaa aaatgatgaa taaattagtt gatatgcttg aagaagatga
    46141 tgatgttcaa gatatatatc ataactggga agtagaataa atagtataag catattgaaa
    46201 tttataagta tttaatcaat tttaacatgt gataaatttt atagaataag aaacactaaa
    46261 atagacatac gcacctctaa cctatatttg cataataata tgtaagcata ggtaaggggt
    46321 gtttttatat ttataggtta agaaatttaa agtaaatttt gagctggact cgattgtcta
    46381 taaataattg atgggtatat aacttgttgc tgaataccat ttatacgccc agttactgta
    46441 tcaataatca tcctaagact acgttctgct gtctcttcca tttttaaatc tataactgtc
    46501 aaaggaggaa tacttcttgc cattagtcgt gaaggtccat tacttgctgc aaatatttga
    46561 atatcctctc caattacaat tcccgattca tgaaatgcat tcatcatacc aagagctacc
    46621 acatcatgat tacaaaaaat tacttttttt agtgaatttt ttgcaagcat tttttgagca
    46681 atatcatatc cactatctat tttattagaa caataatata tagaatctga tagatgtatt
    46741 ccatgttctt tacatgtttt taaaaaagat ttacccctta aagtcataca tgtaaaggaa
    46801 gttgggttga atacaacagc aatatcattt ttaccatttt gaatagcatg taaagctgct
    46861 atacgaccag tttcctcatt atcaatagat acacttgaaa aaccaggtat ttcacgattt
    46921 acaacaacta caggaatttt aggtttattt tttactagat attctatatc atcagcattg
    46981 atacctgtta aaacaattcc atcataataa ttatttgcaa aaaagtattc atcatcacat
    47041 agatgaccaa ctttgtaagg tcgtatgatg atatttatgt ttaaatgttc taaagaaatt
    47101 atgtggttta ttgcttgaag tatattggtt gatgccaact caaatccctc atcctgccaa
    47161 taaaaagcta ttttaatatt attatgttta ataggagtag agcgtttata tccaagctta
    47221 tcagctgaat ttaatataag ctcttgtgta tgtagcggaa tcctgcgttc atttccttta
    47281 ccacttaaga cgtacgagac agttgctgaa gaaagaccac agtcttttgc aatatctttg
    47341 attgttgcca tgataaaatc ctccttaaat agttgcttaa atttgcttat accaataatc
    47401 ttaacatata ttcaactaaa gaacaatatt ctacaaggtg catattttac aggattagaa
    47461 taaataaatt taaaaaaact tcttacttat gttgacataa tttagtttat aggattataa
    47521 tatgcttaaa taagcttatt attaacttaa attaagcaaa gttaagcagg aacatgcaat
    47581 gctagcttgc aatgtgactg taaaggggga aaaggtatga ataaggtaaa tatatttgaa
    47641 gttggtccta gagatggatt tcaaaacctg aaagagtttt tagaaactga taaaaagctt
    47701 aagattattg atggtcttat tgcttcaggg attaaacaac ttgaaattag ttcatttgta
    47761 agcccaaaag caatacctca gatgaaagat gcaaaagaag tagcaactta ttgtgtagaa
    47821 aaatatcctg atgtgaaact ttatgcatta gttccaaatt tatacggtgc taaagttgca
    47881 tgggagtgtg gtataagaga tatatcctat gttatatctt tgagtgaaac tcataataaa
    47941 aaaaatataa atcgtaccca tgaagagtct attgatgagc ttaaaaaaat aatgaatact
    48001 tatccagaca tgaatatatg tattggaatg gctactatat ttggatgtcc ttttgaaggt
    48061 ttaccaaaaa ttgaagatgc cataagattt gctaaacgcc tttgggaaaa cgatatcagg
    48121 gagataaatc tagcagatac aatagggatt gctgacccta agcaagtaag agaaactatt
    48181 agtgcattag ttgaagcttt accagagtgc agatggcaag tacatattca tgatactaga
    48241 aatatgggaa tggttaatac tcttgtggct attgaatctg gaattactac tgttcagtct
    48301 acacttggag gattaggagg atgcccattt gctcctggag catctggcaa tactgcaact
    48361 gaagatttag tatatatgct tgaacgtatg gggtatgata caggagttga ttttgttaaa
    48421 cttcttgaat tatcaaagta tcagaagagt tttgtaaatg gagtatatag tggtcatcat
    48481 ataaatataa agtctgatag ttgtaattgt tagttctatt gattaatcga ttaaaaaaat
    48541 atgttgatta aaaaaatatg ctgattggta aaatagattt attgataaaa aatataaatt
    48601 ataaaataca ttatctaata aaacaaataa aaaaattgag ggggattagt atggatatta
    48661 tagctttact tttattttta ggagttatta ttattgcatt tgtacgtaag aataatgcag
    48721 gtattttggc tctagctatt ggtgtcatag ctgttagaat ttttggaatg gatgataaag
    48781 aactttatgg agctataagc aactcaatgt ttactacact tgttggtata acactactct
    48841 ttgcaatagt gaactcaaca ggagcattaa agcttgttgc agaaaaaatt gtagctgctt
    48901 ctggtaaacg tgtttggctt atacctatag cagtttttat agcaggattt gttgttgctg
    48961 gtgttggacc tggggcaatt ccagcacttg caattatccc agcaatggct gttcctgtag
    49021 ccataacagt tggttataat cctgtaatgc ttgcacttat aggtgaatgt ggattaatgg
    49081 caggtcgtat gactcctatt actccagaag gtcaaattat aacaaccgtt gcagaagggg
    49141 ttggaattga aaatgttatg cctactatct tagcctgtca aactctttct acaattgtat
    49201 tttcaatagt attgtttata attttcaaag gatataaact taaaaaacct ataaatgtta
    49261 tagatagtaa gcaaatagaa aaattcaata taaagcagat aatttctcta ataagcatag
    49321 tagttatgat tgcttttatc ataatttttg atatgaatgt tgggcttgca gcttttgcag
    49381 tttcagctgt acttattttt ttcaatattg ctgatgaagg agaatgtatc aaatcaattc
    49441 catggagcac gatagtaatg gttcttggag taggtgcaat gatgacaatc gtagatgcag
    49501 caggaggtat tgacttgatg agtaatgcat tatcatcact gatgaatagt aaaacagcta
    49561 ctccaattat gagtatttca gcaggtctta tgtctatggt tagttctgct ttagcagtag
    49621 tttatccaac tatgatgcct atgtgtgttg atatagctaa ggccgttgga ggagtagacc
    49681 cactagcact tattgctgca gttggtgttg gaggttctct tgctggtgta agcccacttt
    49741 ctactggtgg ggcattgatt ttagcagcta tgggttcaag taagaaagac tttaataagg
    49801 aagaacaaaa taaggttttt gtacagcttt tcattatgag tgcagttggc ttattggtta
    49861 ttgcagtagt atcaatatta tcatttaatg caataacaca tttaatgaac taattagaat
    49921 aactgaaaat aaatcattaa atttaacttt taatattaat caatataata taatttggag
    49981 gggaagttat gaaaaaagga gcattaagca atataaaggt acttgacctt acaagagttc
    50041 ttgcaggtcc atattgtaca atgatgttgg cggattttgg agctgatgtt ataaaaatag
    50101 agatgccaag aaaaggtgat gatacaagag gttttggacc ttttgtaaat ggagagagtt
    50161 tatactatgc aaatataaat agaaataaaa aaggtatcac tctaaacctt aaatcagaag
    50221 aaggaaaaaa tatattttta gaaatggtaa aacatgctga tgttgtagta gaaaattaca
    50281 gaccaggtgt aatggaaaag ttaggtctgg gttatgatga gttggctaaa gttaacaatc
    50341 aaataattta tggagctgta tcaggatttg gatgttatgg accatattca gaacgtccag
    50401 gttatgatat tattgcacag gcaatgggtg gtcttatgag tataacaggg caagaaggag
    50461 gagaaccaac gagagttggt aatgctatgg gtgatgtact aggtggaatg aatttaacta
    50521 ttggtatact cacagcactc aacgctagaa aaataatagg aaaaggacaa agagtagatg
    50581 tttccctcgt tgattctgtt gtatcgtctc tcgaaactgg tatacagaga tactttgatt
    50641 caggacaacc tgaacttatg ggtaatagat atgcttcagc ctatccttat gactctttta
    50701 aggcaagtga tggaagtttt gtaataggct gtggtaatga caaacttttt gaaaagttat
    50761 gtaaaaaagt tctttttaga gaagaccttt taatagatga gagatttaaa acaaatctta
    50821 atcgttgtga acattacaag gctcttaaac cagaaataga aaaatggtct gttaagcata
    50881 caataaaaga agcagttgac ttaatatcag aggctggagt tcctgctgct cctatctata
    50941 atcttgattg tgttacaaca gatgaacata tagcaaaagc aagagaaatg attgtagata
    51001 ttagtcatcc tattatagga aatatgaaag tcaatggaaa tccagttaag ttgatgacaa
    51061 caaaagctaa aattgatatg ccagcaccat ctctagggga aagtaacgag gagatttata
    51121 atggttggct tggttttgat agtgataaaa taaaagattt aaaagaaaat ggagttattt
    51181 gattaaaaaa tagctaaaca cacttgtgac tttagtcatg ggaggttcag ttagaataat
    51241 atcaaaaaat attaaatcaa tactgtaaat caaatataga attgtcagaa gcatttaaga
    51301 tgggaaaagc tacttagaca ttgagtcttt gtggcttttc ctattttcat taagaatttt
    51361 atattatcag aatagatatg tactaaacta aagtattaac aatttaaatt aatagaaaat
    51421 aaactaccta attatgttga ataaagacta ctttagtgaa aataaactta tagagatgct
    51481 atttaaatta ttttaatgga aatatcaaaa atgagactgc attctcaaaa atgagactgc
    51541 gttttttaag tattttctcg aaaatgagac aaaaatattg ttttatgggt tttattgaag
    51601 aaaaattctt ctgtgaatta caatttaatc aattttaaag ttgaaaatta ttaaaaattt
    51661 agtgaaattt atgtatattt cgtttatttt attaaaaata acaatttttt actaaaaata
    51721 aagaacttca atggtgattg gcatagtact tgctatttta tattaacaag aaatgtagaa
    51781 aaaataacaa tgtataatgg ggggaatatg atggaatctg taatggaaaa tttgaacaat
    51841 cttaaggtgg aggttaagga caaagtctgt gttattacta taaatagacc taaagcttta
    51901 aatgctctta atagtgacac tcttagggaa ctatcacaag ttattgatgt agtatcagaa
    51961 aatgaggcaa tattaggagt tattattact ggagaaggta aagtttttgt agccggtgct
    52021 gatatacgcc agatgcaaaa ctataaaagt gaggaaggca gaaaatatgc aggttatgct
    52081 cagggaattt ttgataaaat tgaagctctt gaaaaaacag taatagcagc agttaatgga
    52141 tatgcattag gtggtggatg tgaacttgct atgagttgtg atattagaat tgcatcagaa
    52201 aaggctatat ttggacaacc tgaagttaat ttaggagtta ttccatgttt tggtggaact
    52261 caaagattat caagacttgt tggaactgga atagctaaag agttaatttt tacagggaga
    52321 caagtaaatg cagaagaagc taaatctatt gggcttatta ataaagtggt tccaagtgat
    52381 ttacttttag aagagtctat gaagatgatg aaccaaatag ttgaaaaagc gccaatagca
    52441 ataagatatg caaaagttgt tattaacaaa gggatagata tggatttaaa gaatgctctt
    52501 gaactagaga aagatattgc aggtttaact tttgctacaa gagataagca agaaggaatg
    52561 aatgcattta tagaaaagag aaagccagtt tttgaaaata agtagctatt ataactaaaa
    52621 ttggaacaat gtagaatata ttcaaaatct aaatttcgtg aaaaaataca tatagtttaa
    52681 ttttaaaagg agttaattta tgaatacggg agtaattata agtttagtag ggattatcat
    52741 agctctatct cttctagttg taatggttat gaagggaata aatattttta ttatagcaat
    52801 tgtatgttca tcattagttg ctataacagg aagcctaaat gtgtatgatg cacttaaagt
    52861 ggattatatg acagggtttg ttggatttct tcaggcaaat ttctttattt tcctaacagg
    52921 tacattaatg ggaaaaataa tggagattac tggtggagca aaatctattg ctaagatgat
    52981 tgtaagatgg attgggaagg ataaagcact actttctatt ccaatagctt gtggaatatt
    53041 agcctatggt ggagtaagtg ttttcgttgt aagttttgca gtgtttccga tagctttaga
    53101 aatttttaaa gaagctgatt tgccacgaag atttatacca gcagctttga cttttggatg
    53161 ctcaactttt gctatggttg caccaggggc accacaaatt cagaatattg ttccagcatc
    53221 aacattaggg acagatatta tggctggagc agtaaatggt tttatatcat gtgcagtaat
    53281 gtttatagtt ggaagtacaa ttttgtacaa aatggtttca aaagaaaaag ccaatggtgg
    53341 tcattttata gcacatgaat cagatatatt tgatgaagca gaagcaacta attctaagag
    53401 agaaaatggt cccaatggtg taattgcctt aattccattg atagtgtcaa ttttaataat
    53461 taatgtaaaa gttaatggaa aagcgatagt accaattgag gtgggagtat ttattggagc
    53521 tttattagta tatttattgt taaataaata tcaagataat actaaaatag ttggacatgt
    53581 tggtgatgca tgtaaaacta cagtagtagc aatatgtaat acttgtgctg tagttgcatt
    53641 tggttcagta gtaaaatcag cagttggttt tgacttcata gttaatgcca tgactaatat
    53701 tcctggtcct cctattgcag gagctgcggt tggaactaca gttattgcag gtatttgtgg
    53761 gtcagcttca ggtggactag gaattgcagc tccacttctt ggaccagtat ttttagccaa
    53821 gggtgtttcc gctgcagcat taactaggac tatggcaatt tcatcagcag cattagattc
    53881 acttccacac aatggatata ttgttactgt aacaaatggt ctttgtaaag aaacacataa
    53941 ggatgcttat atgccaatat tctgggtaac tgttttaact ccgtttattg gaaccatagt
    54001 agcagtccta ctgtttacaa tgttcccagg attgccatag gagaaaagat aaaaggtata
    54061 aattatattt tgatattata aaatcaattt tcaaaatata tacaataaat ttcatgtttt
    54121 aatactgtaa atatgtattt aaaataacaa attgaccata taaggaggaa ttgaaagtgt
    54181 taaataaacc attagaggga gttaaggtta ttgacctaac gtattttgta gcaggtccag
    54241 ggacttctaa aatattagct gactggggtg ctgacgttat taaggtagag ccaagctttg
    54301 gagacccagg aagaaagaca ggggcaacaa tgacaatgcc aatagatgat tataataatc
    54361 ctttttacag cacatataat tcaaataaaa gaggtttgtc tataaatctt aagagtgaaa
    54421 ctggaattga aattatggat aagcttttaa gcgaagcaaa cgtatttgtt tcaagttata
    54481 gaacaggagc attaaaaagg ctaggtcttg attatgaatc attaagtaaa aagcatccac
    54541 accttatctg gggtcagata aatggttttg gcgattttgg acctgctaag gataatgcag
    54601 gatttgatac agttgccttt tgggcaagaa gtggggctat gcttgatata gcagaaaaag
    54661 atacaagtcc aataaatcca cctatagcct ttggagatgc aacaacttct tgtagtttat
    54721 ctggaggaat atgtgcagct ttgtaccagc aagctaagac tggcaaagga caaaaagtaa
    54781 tggcatcttt atttgggcaa gcaatatgga atgcatcatc tttattagca tctacacagt
    54841 ttagtgatga gtatccaaaa actagaaaaa atgctatttc accagtaata aattcttatc
    54901 gttgtaagga tggaaagtgg atattcttaa gtattttaga gcatgaaaga tattttgagg
    54961 cactttgtag attatttgga agagaagact taataaaaga agagaaattt gcatcttcag
    55021 tagaaagtaa gaaaaatgct acagaactta ttaatatttt ggatggtgaa tttgcaaagt
    55081 ttactcaaaa tgagatggtt gaaaaactta ctgctgctga tatagctcat gaaaaaattc
    55141 aacatgttaa tgatgtagtg actgatgaac aggctattgc taataactat atatatgaac
    55201 atacaagtaa aaatggaaat aagacaatgc ttgcatccac tccagttaaa tttggaaata
    55261 ttgaagttaa catgacttgt gatgctccac ttataggaga acattcagat gagatattga
    55321 gagaacttgg atacagtgat tctgatatag aggctctaat tgaatctgga attgtaacaa
    55381 tgaataaaga agcatgtgaa atatgttaat aaacatgtga agtatgttaa taaataggag
    55441 ggaattttat ggattttaga ttaacagaag cacaattaat gcttcaaaga gtagcaaaag
    55501 aatttgcaga gaatgaaata gcaccaatag ctgctgaaac agacaaaaca ggtatttttc
    55561 caagggagct ttttagcaaa atggctaaaa taggatttaa tggaattgga acacctgtag
    55621 agtatagtgg ttctggtggg gcagatatag aaaaggtaat tgttgttact gagattgcca
    55681 aaaaatgtgc agcatctgca gcaatattat caatacacac aatatatgct caagctattt
    55741 tgaaatttgg tactgaggaa caaaagaaaa aataccttcc aatgatggct gaaggtgggt
    55801 gtgtaggtgc ttttgcctta accgaaccta atgctggttc agatgctgca agagctgcaa
    55861 caactgcaat tattgatgaa gaaactgatg aatatgtttt aaacggaact aagtgtttta
    55921 tttctggtgg aggtcaagca gaatcattaa taatatttgc actgacagac ccatcaaagg
    55981 gaataaaggg aatgtctgct atcattgtcg acaaaggtac tccaggtttt tcaataggaa
    56041 aaattgaaga aaaaatgggt attcatggtt cagaaactgc agagttaata tttgataact
    56101 gtagagttcc aaagtctaac ttattaggaa aagaaggaaa aggatttaat atagctatga
    56161 cttgtttaga tggagcaaga attggagttg gagctcaagc tgtaggaatt gctgaagggg
    56221 ctttagaaga aagtatcaaa tattctaaag aaagagtcca gtttggcaag ccaatttcag
    56281 ctttgcaagg tattcaatgg tatatagcag atatggcgac aatggtggaa tcagcaaaat
    56341 tattagtata ttatgctgca gatttgaaag ctagaggaga aaaacacact aaagaagctg
    56401 ctatggcaaa atacaatgcg tcacgtactg caagagaggt tacaaattta gcccttcaaa
    56461 tccatggtgg atatggatat atgaaggatt atccattaga gagaatgtac agagatgcca
    56521 aaataacaga aatttacgaa ggtacttcag aaatacacaa agttgttatt tcaagagcag
    56581 tactaggata ggaggaaaag aatgaatata gttgtttgct taaagcaagt tccagatact
    56641 aatgaagtta aaataaataa agagacaggt actctaataa gagatggtgt accaagtata
    56701 atcaatccag atgatagaaa tgctttagaa gaagctctaa aaatgaaaga tgaactagga
    56761 gcagtgatta aggttataag catgggacct cctcaagcta aaagtgcttt aaaagaagct
    56821 ttggcaatgg gagctgatga agcttattta atctcagata gagcttttgg tggttcagat
    56881 acttgggcta catctacaat tattgctgct gctatagaga aggttggaaa gtatgatgta
    56941 atattctgcg gaagacaagc tatagatgga gatacagctc aggttggacc agaggttgca
    57001 gaatttttag ggataccaca agttacttat gcgaaagaag taaaggttaa agatgacaaa
    57061 ttactagtaa ctcgttatac agagacaggg gattatttaa tagaagcaaa gatgccagtt
    57121 ttattaactg ctataaaaga gttaaacaat ccaagatatc caagtgtcaa aggaatctta
    57181 gaagcttata ataatggaga tgcaaagatt actgtattaa cacttgcaga tttagatgtt
    57241 gatacaactc aaattggatt aaagggttca cctacaaacg tttataagtc ttttgtacca
    57301 gttaaagaca agcataatga aataatagaa ggtataaata aaaaagaaaa agctgagaaa
    57361 ctaatagaaa tactattcga tttgaaacta gtataggagt gttaagatga tgagagcaaa
    57421 agttaatcaa ggtataaatt taaatgatta taatggtgtt tgggtaatag gagagcaaag
    57481 ggaaggtaaa attaatcctg ttacgataga acttattggt gaaggaagaa agcttgctga
    57541 ccaattagga aaagagcttg cagttgtgat agctggatat gaagtagaga aagaagtgaa
    57601 ggaattactt cactatagtg ttgataaagt atattacatc aatgaccctc ttcttaaaga
    57661 tttcactact gatggatatg caatttcaat tgcaaattta atcgaaagaa aaaagccaga
    57721 ggttgtattg gttggtgcta cttctatagg aagagatata gcgcctagaa ttgcaggtaa
    57781 ggttggaaca ggtctaactg ctgactgtac aaaacttgaa atagattcaa cagataataa
    57841 gttattacaa acaagaccag catttggtgg aaatttaatg gccactattg tttgtccaaa
    57901 aaatagacca cagatgtcaa cagttcgtcc aggagttatg gcaaaagctg taagaaacga
    57961 atcagagact ggaattttag aaattgttac tccagaactt actgaaaaaa tgattagaac
    58021 tagattagta gagatacttc cacaagaaaa gaaatctgta aatctaactg atgctagaat
    58081 aatagtatca gggggaagag gattaaaaag agcagaagga tttgagctta taaaagaatt
    58141 ggctgataaa ttgggggcag agattggtgc ttcaagagca gcagtagatt cagggtggat
    58201 agaacattct catcaagtgg gacaaacagg aactactgtt agaccagaac tatacattgc
    58261 atgtggaata tctggagcaa tacaacattt agcaggtatg agtgattcta aatatatagt
    58321 tgctataaat aaagatgcaa aagcccctat ttttagtata tgtgactatg gaatagtagg
    58381 agatttatat gaaattatac ctgaaatgat agaatcatta aataggtaac ttttagaaaa
    58441 cattgaatat gtagaatgat aagtcttata atattgtatt gtaagactta ttatttttgc
    58501 tgaaggttat agtggggaga tgaaacaatg aaagagcagt ggtataagga tatatttgca
    58561 agagtattat ctatgactga tgatggtttt attgttgtaa atacaagtgg agtaataata
    58621 gatattaatg ataaatattg tgacttttta ggaaaagaaa gaaaagatat aataggacaa
    58681 aatatacaaa gtattatacc aaatacaaaa atgctagatg ttatgaaaaa taagtattgt
    58741 gaagaaggag ctatacatca ttattcaggt ggaaatacaa aagaaaaaag tgtaatagta
    58801 agtaggtctt atgtggaaaa tgacaatgga gaagtagttg caggagtagc tcaagttaaa
    58861 tttagattgc aatcatttga tgtagctaaa aagttaatgt cagaatatat ggagctccaa
    58921 tattataaag agcagtttaa ggataactgt ggttttgaca agctcatagg tgaaaataga
    58981 gacttcatag aacttaagaa aacaggtgtg aaagcttcta aaacaaactt tccagtactt
    59041 ttaacgggtg aaacaggtac aggaaaagaa gtctttgcta gagcaattca caataatagc
    59101 agtaggtcag ataaacctat ggttagtata aactgcgctg caataccaga agaattatta
    59161 gagtcagagc tatttggcta tgacgaagga gcttttacag gagcaaaaaa gggtggtaaa
    59221 aaaggtaagt ttttagttgc gaataatggt acaatctttt tagacgagat aggtgacatg
    59281 cctttgacca tgcaagcaaa acttttaaga gttcttcagg aaagtgagat agaaccagtg
    59341 ggaggtctta aaactataaa gatagatgta agagtaatct ctgccacaag aaagaattta
    59401 agtaaaatgg ttgaagaggg attatttaga gaagacctat actatagatt aaatgtaata
    59461 aacattcata tgatggaatt gaaggacagg caagatgata ttttattgct agcaaattat
    59521 atattaaaca aattaaatgt tgaatacaag gaattgaagg ttttaagtga taaggttaaa
    59581 aattgtttta ttaactatac ttggccggga aatataagag aactacaaaa tgtaataaaa
    59641 agtgcctatg ctgtaagtga tgatatggtc attatgatgt gtgaccttcc atctaagatg
    59701 gataatatca gcagagtagc tcaatgtaat gtggatagca attgttcaat tcatgaaatg
    59761 gttgagaatt atgaaaagag cttaattatt gatgtgttaa ggaagtataa ttggaaatgt
    59821 tctaaggcag cagaggttat gggaatacac aagagtcttt tatataagaa aataaaaaag
    59881 tatgaaattg aattaaataa ttaagataaa ttgaattaag gcaatgctaa aaaagcgcct
    59941 ttattcaaag cgaactgtat aaactgtttt atgcagttaa aacgtgtaaa agtagatgtg
    60001 aagtactaat gtcaatcatt agtacttttt tattatattt ataattacta tctatatttc
    60061 agtatctttt gatatctaag attattatgt ttaatttagg atataacaaa accctcttag
    60121 ttatggacag ttttttatat tttaactgtc tactaagagg ggatagttta gtttaaattt
    60181 agagtaaatt ttatctagca tttataaaaa atattttgaa tagctttttt gttatttagt
    60241 cataattttc tacttcttta tcaagttctt tgccacaaga atcacactta tatatagcat
    60301 tgtatccgta atcatattca tcaactattt tcttttgtct aaatacacca ccacactcac
    60361 ataggaaacc aatttttata agtgtaacga taaattgtga ttttataaat tttatatcat
    60421 tacatttatc gttagtgtaa aatgtataaa tataagagtt atcgcactca tctcttaatt
    60481 caaatctttc aatatatgtg ttatttttta attcctcaaa ttcttcttta gttaaatatg
    60541 atttttgttg caattcatgt aaacgcttaa tttggtccat tatttatatc ctcccaataa
    60601 ttttagtatt ttaagcttag ataaggaatc taagttttat taaatttatc ccaaggaatt
    60661 atttaaatca tatttagttt tattaattac aacatatata aattacacga aaataaaact
    60721 aattgtaaaa ataatatcct gtgaaaacct aaactactaa ccccttacta acccgaaaac
    60781 taaaaaaaga aaatatatcc aaatataagt gatatataaa taaagatgtt tcatataaat
    60841 ttaactttaa atattctgac aataatatat ataaatatat tatagttaaa atataccaca
    60901 tattttgggt attgtatact ggaattagag taattaattt attttttaac atacaaatga
    60961 ttttatgaaa aaaaacaaga ctcaaaaatt tttatattct ttgatagaat aaaattgaga
    61021 gtaaatttat tgaattttat aaaatttata aggggtgagt ctaagatatg catgaagata
    61081 aaaatgatat atttgaatca atagatactg aggattttga taataaaaca gaagaagaat
    61141 gtttagagct agtaagaaaa aatggattga atttaatata cataaaaaat caaacagaag
    61201 agatatgtct agaggctgtt agacaaaatt gtaatgcaat aaaatgtgtt cagaatcaga
    61261 cagaaaaaat atgtatagaa gcagttaaac aagattggag aatgttagaa tttgtggaag
    61321 agccaacaga agaaatttgc atgttggcta ttaaccaaga tggaacagca ttaaaatata
    61381 tagaaaatca gacagaggag ttatgcttaa gagccgttga aaaaaatggt gcggctttgg
    61441 agtatgtaaa agaacaaaca gaagaaatat gtatagaagc agttagaaac agcgaatttg
    61501 gattggcaag agtgaaaaat caaacagaaa aaatatgtat ggaagcagtt aagcattgta
    61561 gctataatct aaaatgggta gaaaatcaaa cagaagaaat atgtatggaa gcagtgagac
    61621 aaaatgggct tgatttgaaa tttgtaaaaa atcaaacaga aacaatctgt ttaagagcag
    61681 tgagacaaaa tggaatggca ttagaatttg taaaggaaca gactgttggt atatgcttaa
    61741 aggcagtaag acaatatgga atggcattaa aatttgtaaa agaacaaaca gaagaaattt
    61801 gtacagaagc tataaaacaa gataaaagag cacttagttt tgtaaaagga gataaggaaa
    61861 aatacaaggc tctatatgat aataatgaac catttgcaaa gagatatgtt agaaatgtaa
    61921 tagaaaaaga aaacagagca ttgattaaaa aaggagaaga aaatgcaaaa atcaaaattg
    61981 caggaaaact ttatgataga ggcatgtctt ttgaagatat atcagatata gttgagattg
    62041 aaataagcaa gttaaaagtg agtttaggtg ttttttaaag taataaatgt aggtgttttt
    62101 tatgggaaat agttaataaa aaaataatcg actagctctt tgtaggacag caaaattagt
    62161 gatataattt gatgtataat aaattatttt tattagataa gggggaatta aagttgaaga
    62221 ttacagtatt ataccaaaca agaagtggaa acacagaaag ggtcgctaag ctgatagaag
    62281 agggcgctaa aaaggtggat ggagtagatg taaagcttat gagacttgat aatattgatt
    62341 tagattattt aaatgaaagt aaagcagtaa tatttggaac acctacttat ttagcaaata
    62401 caacttggga agtaaaaaaa tggtttgatg aagattcaaa aaaagttaat ttagctggaa
    62461 aattaggagc tgtttttgct acatgtgatt atatatgtgg aggtccagat gttgcgatac
    62521 ttactatagt aggacatttg atggttaaag gtatgcttgt gtattctgga ggtggttctt
    62581 taggaaagcc atttatacat ttaggacatg tacattcaat tgaaggtcca gagttacaag
    62641 atgagaaggc tataatattt ggtgaaagaa ttgctactaa ggcaaaagaa ctatttgctt
    62701 aatttctata tgcataataa tgattagagt aaatttaggg ttttaaggga gatttgaagt
    62761 aaaagttata aaataaaaaa ttttccataa aattactcaa gatgaattat aatataatta
    62821 taaataaatt atattattaa aatatttaaa atcaaacgtc aatagcgagg gaagtttatg
    62881 gtatggcata tagaatatga gattttttct gcaattatag ttattttttt aatggtatac
    62941 ttttttagaa gtaaatttat acctacttta caaaacaaaa tatattgtgc acttttaata
    63001 ttctcatttt tatttataat ttcaaatatt ttaggttcat tttgtctaaa taatatagac
    63061 aaaattccaa tttttattac ttttttattg aatcagatat acttattgtt attgccaata
    63121 ccagcagcac ttgtatcatt ttatgttatg gctattattt atcaagatat aaggtatatg
    63181 aaaaaaagat tattattttt atctatacca cttataattt gtataatctt atctattaca
    63241 aatcctttta cgcatattct atttggattg tcaaaagaaa caggttatat acgaggttgt
    63301 ggatatgttg caacttttgc atcttttttc ttttatgcaa tatattcagc atttttatct
    63361 tttaaatata gaaaagcaat gcatgaatca aaaatatggg ctattagagg ttttcttata
    63421 gtttcaattg tggcaattat cttacaggca atttttttac agtatcttct tacaggaact
    63481 gcatgtgcat gtagtttact tttgacatat ctttctatgc agaatcgagg tcttattatt
    63541 gatgacctta ctggtgtact caatagacaa tcttttattc aagagctaga tttgaatatc
    63601 aatactgaac aatcaggatt tattattaca attgcgcttg atgattttaa gtttatgaat
    63661 gaaacttttg gaacaaaaaa tggagatatt gcactaaaag aagttggaaa atatttgatt
    63721 cagatacatg atgtaaacca tgtatataga atagggggag atatattttc tattgttgtc
    63781 aatagtcaat taggtataga accagatgat attatcagaa agatagaaga aagatttaaa
    63841 aagccttggc tagtagaaga gataagtttt aatttagcaa ctagtattgc tgttgtttat
    63901 tacccagaaa atgcagaaac gacagaagat gtaattgttg ctatagattt ctctatacat
    63961 gaagcaaaac gttctgagtc aaggcgagtt gtttatgcag atgcgtctat aagtgaaaag
    64021 ataaagaaga aacatgttat taaaaattgt ttaaaagaag cattaaaaaa tgatgggttt
    64081 gaagtgtact accaacctat attttctaat agcaggggca ggtttacttc agcagaggca
    64141 ttacttaggc tagaacacaa agagttaggt tttatacctc ctgatgaatt tattccaatt
    64201 gcagaacaaa caggattgat taactcaatt ggattagtag tctttgagaa ggtatgtaga
    64261 tttatagcta gtgatgagtt tgaaaattta aaattggata atatagctgt gaatctttct
    64321 gtagtacaat gtatgcaaaa aaacttagct gatgatttac tttatcttat gaataaatat
    64381 aatgtatcac caactaaatt taaacttgaa attactgaga ctgtggctat gggctctttt
    64441 aatataataa aagaaacaat ggaaagatta attgatttag gtgttaagtt tgcacttgat
    64501 gattttggaa ttgcttattc tggagttact aatatgcttt ctttaccatt ttcagtaatt
    64561 aagttagata agagtttgat ttggtctatg aatgaagata gtaggcataa acttacagtt
    64621 gagacgatta tagcacttat aaataaattg aatatgaagg ctgtagcaga aggtgttgaa
    64681 accattaagt gtgctgaaga tttaatagct atggagtgtg aatatttgca agggtattat
    64741 ttttctaaac cagttccaga agatgttttt aaaaatttgt tgaaagaaaa tacttttaca
    64801 agttaacacc ctttattttt ttaattacaa ctttgttcat tgacactgcc agcgatatat
    64861 tataaaatta acacaataat aaatattaaa tttattatac atattattaa tattaattaa
    64921 tggagtaaag atttattata tattttattt aattatccta aagtgagaaa ggaagatgtg
    64981 acatgaataa aaagaaaata ttagtgccaa ttgatgggac agaaagaagt atgcattctt
    65041 tggaatttat aaaaggaata tttaaaaaag atgaagttga agtagaaata atgaatgtaa
    65101 aagaactagt atttattgat ggcatatccc tggctgaaga gataaaaaat tctgaaaatt
    65161 taggaagaag aatcttggat aaagcagcag agataatggg agagtatgat gttaaagtac
    65221 attttacttt tggatatcca ggagatgaga taattagaaa agcaaaagaa gataatgtag
    65281 attttatagt tatgacaaaa tctactaaaa aaggtcttac aagaatgata ggttcagtaa
    65341 cagcaagtgt agttaaacaa gcaaaatgta tagtgatgat tgtaccggag tagaattaga
    65401 aaggtatttg aaatatgaat aaaaagatag tagcagtttg tgaaagtgaa agaagtttaa
    65461 actctcttaa gacagctgca aatgatttag gatttgattt agtttatgaa attcaagaaa
    65521 atgataatat aaaaaatgaa ctttctattt atgatataga agatgcatcc atagtgttat
    65581 ttgttacaag tgattctata gaaagcatag agaagattga tagatttata gatagagaat
    65641 tttatgaagt tgatccaaag tatataatag aggatgcaaa atctatagta agtgaaattt
    65701 taatagactt aaattaatcg tgggtgtcgc actaagaata gagcgacgcc tttttatata
    65761 ttttacacaa gaaataaaga ggttgtatca aaatatagat aagactcttt ttcattgttg
    65821 aaatgatgaa aatatatttg atttcataca aaaaagagta cctcataact aaaaagttca
    65881 ctttgagaca ctccattttt atatgttagt tgcatttaag gtaaaatata agtttaatca
    65941 tgttgaaata actgaattac atcttctaaa tgattgtaca ttgatgtata acctaagtaa
    66001 gagtctttac tatcaaatgc aatcattatc ttgttatggt ggctaatcat atccttgaga
    66061 gaatttctat atttaaaacc gaagtattgg ttagaagaaa ctgttttagg tattaactca
    66121 taatatttta taaaaattgg attatgagaa gctaaaatta tctctttgtg aaattgcaag
    66181 tcagcatcat aacattcttc tatcaaacca tgagaaacct tatccaattc ctctattgac
    66241 tttaggtaag tatattttat tttttgaagt tctttagatg tagcatttaa aattgctagt
    66301 ttagtagctt cactttcgat aagttgtctt gctcttaaag attctacata aaattcttgt
    66361 atgttatgat ttttatagat ttcaccatca tcaaataggt caactttttt aaatccttca
    66421 actataggac ttgaataagg cacagctcta agtattcctt ccttacagag tatatttatg
    66481 gcatttctta caggtattct acttatgtta aataggtcag caatctttct ctcacttggt
    66541 aatttactat taattttaaa agttccattt agaatgttta atttaatata atcaataatt
    66601 ttttcagtgg catttaagct tttcataaaa actcctaaac atataatttt tttatgattg
    66661 tattatatca tagttaagag ttaaatctac ttttttataa tatgtataag acaggataga
    66721 ggccaaaata gctataatag ccaagataaa gtatccatat tgtattgaag tatattccga
    66781 tattttacca actatcattg gaaatacaga cattcctata gcataaattg cttgaaaaaa
    66841 acccattgca gtagatttct gatgttttgg tacatttttc atagactcgc tagtaaggta
    66901 agaaaggagt atacctgtag atatacctgg tagtacttgt agtacaaata ttatattaat
    66961 attttttatt gttggaacta aaaagcaata ggctgaaact aaaataaaaa ctaaaggaat
    67021 ccaaaatttt ggtccatact tagtacaaaa tttagtagaa gcaaagccag aagaagcaac
    67081 agcacacacc atgtaaaata tagaagatag acctatgagg gtagaactag aacctaagtt
    67141 tttaagaatt tgagtagtaa atgacattgt tgtagacatt tgaataccct gttgaattaa
    67201 tgccataaag gaaaaaaata caagtctttt atccttgcag atagataaat attttttaat
    67261 tgatattttt tcaggtattt tttttgaatt atgatttttt atatttaagg ctagaatcgt
    67321 tccaataact gaagacaata cactcatgat acataaggct gtcattccta atttttcata
    67381 aaataaagta ctcataacaa atccaatcaa cattcctaga ttgtttacca atattatcgt
    67441 acttgtagct ttttgttgat gttctgtaga aaaaaagttg gtatagtgaa ccatgtaaga
    67501 aatccaagtt gatgatgata ttccagataa aatgttagct ataagaaaac cattgcctcc
    67561 aggagaaaag actcttataa gagatgctaa accagcaaag aaaattccag acagtataaa
    67621 tattttatgt ttatttatag aatcagcaaa tactccaaca ggaagcctta ataaacattg
    67681 tgatattcca tatgcaccta ttattatacc aatcatattt gtagatacat tacatgcact
    67741 taaatatgga ttttggaaag gtatatatac atattgtgaa aaccagaaaa atgtaacaat
    67801 agaaagtaaa agtaattttt gattagatat ttttttcata ttatcctcca tatggtattt
    67861 ttataatgca aataatatac catttagatt ttttaatcaa gtactttctc tattaaaaaa
    67921 aatttaaata tataattatt atttacaaaa aaattatact ttatagttga attaagaaaa
    67981 cgcttatgat actataaagt taacaaattt gaatatataa cagtagacgt gttactggta
    68041 atgcaggcaa gatcgaatca atttttatag attatctata gagtactatg ggtataatct
    68101 atttatttgg ttcgattttt ttgtttaatt ggccataaaa caaaaagcct atagttgaaa
    68161 atggaggatt ttttatggat tataaaaata tagctcaaga aattctacta aatgtaggag
    68221 gaaaagagaa tgtaaatgaa gtgactcatt gtatgacaag acttagattt aaagtcaaaa
    68281 gcgcttctaa agtgaataag gataaattat ctaaaactga aggagtaata actgttgttg
    68341 agagtatggg tcaaatacaa gttgtaattg gaaataaagt aaaaaaagta tatgatgagg
    68401 ttataaaaat tgtacctcaa tcaaataaca taggtaaaaa gaatgaaagt caagaaaagc
    68461 aaggtataat taattctata ttatcagcag tagctggtat atttacacct acaatacctg
    68521 ctatagcagg ggttggtatg attaaaggta ttttatcagt tcttgctatg tattatatga
    68581 ataaaaatgg agtagatata aaagaaacgc aaagctatat tatcttaaat gccatggctg
    68641 attctatatt ctattttatg cctattatac taggatatac tgcggctaaa gtatttaatg
    68701 caaataaaat aatatctatg gtattaggag ctacactttg ttatccaact tttactgctt
    68761 tgatggcagg tgaagaatct gttagatttt taggattggc agtaacaaaa gctacgtata
    68821 catcatctgt tattccaata attattgcta tatgggctct ttcatacgtt gaaaaagtat
    68881 tagaaaagta tatacctgag gtaattaaaa taataatggt tccaacttta tcattggttg
    68941 taatgttacc tgcaacatta tttttatttg gaccaatcgg aatttatata ggaaatgtca
    69001 taaacttttc ttataagtat atttatgaat taagcccagc attgtgtgga gcatttgtag
    69061 gtgggttatg gtgtgtgttg gttatatttg gtgctcatag agcattatta ccaataggta
    69121 taagtgatgt tgctcaaaca ggaagacaga atttattggc atttgcagga gctgcaaact
    69181 tttcacaagc aggggctgct ctaggagtat tctttaaaac taaaaatcaa ggactaaaaa
    69241 caatttctat gtctgcaact ataacagctt tatttggtat aactgaacct gcaatatacg
    69301 gtgccaatct tagattaaaa aaacctatgg tatgtgccgt aatatgtggt gcatttggag
    69361 gtgcgataat gggaatgggt ggagcttatg gtaatgcatt tgcaaaccaa ggtgttttaa
    69421 ctatacctgt atatgctgaa gcaggtgcat taggtttctt aagttatcta ggtggttgtg
    69481 ctatagcatt ttttggttca gctatttcaa cttatctagt tggatttgaa gatttggaag
    69541 agtcttctaa taaggaaaat tcatctataa aagtagaaac gaaggatggt gttattgata
    69601 taacttcacc tgtagagggc gaatgtatag aattgtcaga agtaaaggat gatgtatttg
    69661 cttcaaaagc tatgggagaa ggtatagctg tgttacctac aaaaggagta ataacagccc
    69721 ctactgattg tgaagtagct tctttatttc caacattaca tgcaatagga ttaaaattag
    69781 ataatggagc agaaatgtta atacatgttg gaatcaatac agtagagtta aatggtaaat
    69841 actttacaaa acatgttaat caaggagatt tagtgaaaaa aggtgataaa cttatatcgt
    69901 ttgatataga taaaataaaa aaggctggtt atgatgtaac tacgccagtt atagtaaaca
    69961 atacatttga ttttggacaa gtagtttctt gtaaatctag ttatgtttca accaatgata
    70021 atataatttc attagtatta gctggtaatt aagttaattt gactagagat aagtaaattg
    70081 atttaaaagg aaataagtaa atcaacaatt aaatacatct aaaagtaagt ttattgcaat
    70141 gaattgttaa agaaaataat taatatggag taaagctatt gcaatgaagt aacaaagaaa
    70201 ataattaata tagagtaagt ttattgtaat gaattgttaa agaaaataat taatatagag
    70261 taagtttatt gtaatgaatt gttaaagaaa ataattaata tagggtaaat ctatctcaat
    70321 gaaataacaa agaaaagagt taatatagag tgaacttatt gcaatgaatc aacaaagaaa
    70381 ataatcaata taaaaaggag aaatatttat gaatacagga tttccaaaag actttttatg
    70441 gggagcatca tcttctgcat ttcaagtgga aggagcttgg gataaagaca ataaaggaaa
    70501 aaccgtagcc gactataatt cttttaaaaa gtctcattta caggcagata ctaaagtcgc
    70561 atcagacttt taccataatt atgaagaaga tattgaatta atgaaagaat tagggatgaa
    70621 aacatatcgt ttttcaattt catgggcaag aataatacca gatggtgaag gagagataaa
    70681 ccagaaaggt ttagaatttt ataataagat aatagacaaa ctaatagagt gtgatattga
    70741 gccattcgta actttatacc attttgacct tccatttaaa ttagtagaga aatataatgg
    70801 ttgggaaagt agagaaactg tctatgcttt tgaaagattt gctaaaatat gctttaagca
    70861 ttttggagat agggtaaagt attggcaacc tcataatgaa cagaatttaa ttgttagagt
    70921 ggaggagaga attaatatat atgatgaaac agattcatgg aagatagata aaatgcgtgc
    70981 tcagatggat tataatcttt gcttagcaca tgcattagca gtcaatgcat gtcatgagat
    71041 gataaaagaa agtaaaattg gagcagcagt atcatcatct gtaacatatc ctcttacttc
    71101 taagccagaa gatgtatatg cagctagaat gaatgataat tttaaagtgt actatatgct
    71161 tgatatgcat cattatggag aatatccagg gtattatatg aagtatcttg aaaaaagaaa
    71221 tatagttcct cacatggaag atggggataa agagatactt aaaaaagcta aaatggattt
    71281 tatagctgta aattattata ggacaaattg tgcagaagct ttacctgaag attcacaaca
    71341 tccatttgga ttaagagaag gaactgttga ttttagtatg tatggactat ttaaaatgtc
    71401 aatgaatcct aacttagagg cttctgagta tggagcagca atagacccat caggtcttag
    71461 agttgcctta aatgaatatt ggcaaagata tcacttacct gttataataa cagaaaatgg
    71521 tctaggagct aaagatatat tagaagatgg aaaaattcat gatgactatc gtatagacta
    71581 tttaagaagt catataaatg catgtaaact agctattgaa gatggtgtag agatgattgg
    71641 atattgtcca tggtcattta cagacctttt aagttcttct caaggtttta ataagcgtta
    71701 tggacttgtt tatataaata gaactgacca tgaagtttta gatttaaaaa gaatcaagaa
    71761 agatagtttt tactggtata aagaagttat agagaacaat ggaatagtaa aataaacata
    71821 aatatatatt gagggtttta gtatgtacat tacaaaggta ttaaataatt cgttgctact
    71881 tgcaaaggat gataatgatg aagaaataat attgatgggg aaaggcattg gccataatta
    71941 taaggccggg tctgagttaa ataaaaaaga tatagaaaag atttttgttc ttcatgatga
    72001 aaatataaaa aagagtatta tacaattggc aacagaaata gatgcagaat attttggtat
    72061 agctcaaatg ataattgcat atggaataga aaaatataac ttaaaactta tgaaccatat
    72121 atatttggcc ttaactgacc acattgcctt tgcagtgaga cgttttaaag aaggtataat
    72181 gattgaaaat cactatttgt tcgaaatcaa ggaatttaat ccaaaagagt atgatatagg
    72241 aaaatatgct attactgttt ttaaggaggt tcttggttta gacctaccag aagaagagat
    72301 tggtaatata gcaggccatt ttataaatgc acaacaagat aatccttata gtgatagaaa
    72361 taagagaagt gctaaaattg taaatgctat tttgcaaata gttcattatc acttttctat
    72421 tgtatataat aaagagtcat tttattatag gagatttgta atgcatctaa aggccttttc
    72481 acaaagattt ctggctaatg aaccatcaag agaaaaaata gattttatat atgagcaagt
    72541 tcaaaaaaat tgtaaggaag agtatgaatg tgtgaaaaag gtaggagctt atatgtataa
    72601 ggaatactcc agagaattac caagacaaga ggagttatat ttgatgattc atattcataa
    72661 gattttagga gaattatgcg aaaatagtta gaatatctta atatgctagt aatattataa
    72721 aaaattaaaa attaactgca ctttaaatat gaataattgc attacttaag ggggttgtct
    72781 taaaattgat ttttttaatt aaatttgaag ctcaactcct tttttaaacc tttatatcat
    72841 tacaacttta atgtttatac gactgtactt tagatgtata tctacttttt acatttctca
    72901 acatgcaaac ctaccatttt ttgcagtatg ttaattgaaa taaaccattg agttaaccct
    72961 aaatttattc tggacttata ggaatagttc caaagatact ttaaaatatt ttctggaata
    73021 attgcttatt tcacatatgt tttattgtga tgttttgatt taataaattc ttcaactctg
    73081 tatatagtaa atgtattatc atgtttgttt tattcaagca cacttataat acgcttgatt
    73141 ttttcacaat gatgaaatat actaatgggt gttataggta taagaatcgc attacacttg
    73201 aagaagtaag tgataaatga gatataaatc ctcatatgat aaactactat ttcattgagg
    73261 aacatattct aagtgatgtc aagatactac aatatgacta aattcctagt gataaaaaag
    73321 tctacgaatg agtgtagaaa ggggaactaa gatgaataaa gttttaatta tagatgatga
    73381 taaagatctt tgtattttgt taaaaaagag tatttcaatt gaacagattg aagcaaacta
    73441 ttgccattct gggagagatg gactggttga actttcaaaa caagattatc agttagtagt
    73501 tctagatgtg atgatgccag gtatggatgg ttttgaaact atggaacaaa tacgaaaata
    73561 tagcagtatt cccatcttaa tgctgacatc aaaaagcgat aattacagca aagtgcatgg
    73621 attgcgagct ggtgcagatg actatctaac caaaccattt gaaattacag aatttactgc
    73681 tcgtgtactg tctttaatcc gacgttacac ccgttttaat ccaaaaaatg aggagccaca
    73741 gcaactttct ttcaaaggtt tgttgattga ccttgaccag catacagtta ctaccaatgg
    73801 cgaacctatg ttgcttccac ccaaggaatt tggtgtactt ctttactgtg caaggcatca
    73861 gggtaagatt ttgacaaaac aacagattta tgaagccgtg tggggtgagc catatgtata
    73921 tgatgacagc aatatcatgg ctattatcag tcgcctaaga aaaaaaattg aactagaccc
    73981 atcatctccc atctatttgc aaacaataaa aggaattggg tatcaattca acacggaggt
    74041 atgaaaatgg atgaacaaac gataattctt ttcttactct tgctgtcgat tggtctactt
    74101 tttctttcca tatttgcttt ttccaagctt gggcatattt acaagcgcct aaaagatata
    74161 gaggagatac tggctgatgt acaaattgga gacgaaaatc gtaaaatact aattaagcca
    74221 tgtgatgtta tggctccatt ggtttatcag cttaatgaga ttgtctacga ttatgaaaat
    74281 aagttacttt ctctgaaaaa gtcggataaa gctagcaaac aacttatgac aagtttatct
    74341 catgatgttc gtacaccatt aacaactctg attggttatc tggatgctgt acacagtggt
    74401 atagttatcg aacaagagcg ggaggaatac cttgaaatcg ctaggcgtag agcctacgac
    74461 ctcaaggatt acattgatgt tctttttgac tggtttcggt tgaactctga tgaatttacg
    74521 ctgtcaatag aatctgtgga aattgcagag ttgtcacgca atattttgaa agactggatt
    74581 cctatattcc atgaaaagaa actgaatttt gaaattgata ttccagaaaa tcgactaatg
    74641 gtaaacctcg acccagatgg atattcccgt gtggtcaata atctggttca aaatgttctt
    74701 gctcacagta aggctcggca aatcaagatt accatgagtg aggattccag aatggtatta
    74761 ctccgtgttg aggatgatgg tgttgggatt gccagagaaa atttaccaca tatttttgag
    74821 cgactgtata agtgtgataa aggacgttca gaaaaaggaa gtggtcttgg tctatctatt
    74881 gtcagtcaaa tggtggagcg aatgggtggt caggtttccg tagaaagtga gattggaaag
    74941 tataccgtat ttacagtgag cttaccatta atataaaatt gtttttcccc catgtgacat
    75001 gtatacacat ggggattttt tgtaagttat aaagttgcaa ggttaataca aggttgttgc
    75061 aaggttaatg taagattgag gtggtatgat aactttaata aacaaaggag gcttttatta
    75121 tttatgaata atttaattat tgaaacaaaa aatctcacta agcaatatgg tgctcaaaag
    75181 agcgtttcta atttgaatat tcacgttcag aaaggtcgca tttacggatt gctaggaaga
    75241 aacggtgcat agatatatag acaaaaattg ctaaacagct aatgtagatt tagatagtga
    75301 ggggagtgta taaacacgtc cctctttttt agatgtgttc tgattgtttg agataaactc
    75361 taacaatctt ttatgctggt ctgcaaaatt aaacttaatt gtaatttcgt tgttttcgtg
    75421 gatatagatt gtatcaatca attcagctaa tattccacgg tttaactcgg ttatgttctt
    75481 atgtttcaag aacatttgta ggtaagggtc attattgcct acgccttttg aggaaagctc
    75541 aatctcggct ttaagattga caatcgcatt tttcatgctg tctgcctttg cttcaaattt
    75601 ggatttcatt cttacatatt cagctctggt aatctcgcca cacttccagt ccatatacaa
    75661 attgtctatg acattagtaa tcttttcaag ctcatgttct ttggtttgta attgctttgt
    75721 caatcgcaag gactgattgc atacagcttc ttgcttattg atttctgtga ttacctctgc
    75781 catgttacta acaagagaaa tttgtacttg aattgcattg agtacggctt ctgtcaaatc
    75841 ttctaatgaa atgctgtgac ggctacactt atctttattt tttaaagcat aagtagaaca
    75901 cacataataa gtatattctt tggtttctcc atttgccatg ttctttttgt tggttttctt
    75961 tgtcatgctc ttatcacaat ctgcacaacg taggaaacca gaaaacagat agacatttct
    76021 ttttgtagga gcagtacggg tatcacgttg agataaagac tgtgccattt caaaggttac
    76081 tttgtcaata ataggttcgt gagtattctc tacgataaac cattcactct ctggcgttgc
    76141 tatcgcttta tgaaccttat agctgattac tcgctgtttc ccttgtacca tatccccgat
    76201 atacattcga ttacttaaaa ttcttgctat cgttgaaatg ccccacatac cgtcattctt
    76261 tgcttgatta ggtgttttga ggttcaagcc ttgactgtgc ttgtagtcca taggtgtagg
    76321 tacgcctaat tcgttcaagt gtcttacaat accgatttta ctcataccgt cctctacata
    76381 ccagcggtaa atatcccgta ccacttgtgc agggacttca tcaatgataa ggcaattttt
    76441 atttgttggg tctttcttat atccataagg agcgaaagcc ccgataaact cgccattacg
    76501 acgtttcata ttaaaggtac gtcgaacatc attagaagtt cttgctgaat aacggtcatt
    76561 catcaatccc gtaatcggaa cgtccatacc atctgtaatc gactctggat ttttgtaagt
    76621 gtcaaatgac ggacttccca gacagataaa tcttgtgtta taaagtggaa aaagttcttc
    76681 caaataataa ccttgatctg cataatttct gaatgttcgt gctaatgtct tgcaaataat
    76741 acaattcaca agaccagctt tcacatcatc aatcatgcgg ataaactcag ttcttgcgtc
    76801 atcagttgta ccgctgatac cgtcgtcgat ataaatatcc acaaggatat attcttcttc
    76861 aaagaaattt tccaagtatt cacggataat ctttttctgg ttcgtaacac ttaaactttc
    76921 gtcgttgccg tcgtcctttg ataatcggat atatacggca attctccata ccatgtgatt
    76981 tttgctattt gattttttaa cttttctaac tctcggcata ttgatttctc ctattagaaa
    77041 agtcatttat cactttttta ttataccata tttcgcccat tttttcagta actttttagg
    77101 ctcttgaagt aatttatcaa gcaaaaatca agcgttggag cgtcctcgtt aaacacgact
    77161 tttacaagtg ttttaccaca taagaagcag tagggattgt ttaattcctc tatgcaggca
    77221 gataaacgtt ctgtgttgga aagagccttg tcggtattga ttgacttgac cgcttctaaa
    77281 taatcggaac atactgttgt ctgcttattt cctaaatcat tcaatagata tacccccttt
    77341 gctttgctgt ttagcagttt ctacttatat acaagcaggc agacggcttt ggaaagctcc
    77401 gttagtatct caactattcc cattcttgtg ggcagaaccg caccatgcgg acgtatcatt
    77461 attctgtgag gataggtcgt ggcaaagcga cttttccaac ggtcgctctc ggatcactgc
    77521 gtgggtcgct cgctttcttt tggaaaggtc atggcgtaca gtccccgtgg cttgctatct
    77581 cacaaacgta tctgtctgct ttattcagtt gtcaaagacc agacgggcat aatcaatccc
    77641 gatatgaatt agaagcgttt aatatcaaag tttaagattt tacgaataat cgcttctttg
    77701 ataaaacctt tcatttccaa atctaccgca agacgtaagt tgttgttatc gtcgtaaaac
    77761 ggacgcatac agcactgatt gatatatggg tcataaaatt ccaagatttt tgaaattgct
    77821 gtttcgtcgc cgtcgcaggc tttggaaata accgtgaaag tcggtgtcag ctcttttggc
    77881 atttttcttt ttcctcctca atcagttgct ttaacttgtc tagtgcttgt attctgcact
    77941 tcgttacatt cgctctggaa cagtcaagca ttttcccaat gtaagtgtcc gtgtccccaa
    78001 tgaaaaaata ctgtaaaacg atattacgct ttcgttcttc aatagctttc aatgcacgag
    78061 ccagttgttc atcttcgatt gatacttttt ctccacagac ttcaaatact gcaacataat
    78121 ccgtagaata tgtatcttct gtacctatgg aatttaagag gtcgtccata atttcggcga
    78181 atggcatttc ttttttctct gaacgacgta tcgctcgata gaagtcaatc gctctatgac
    78241 gtataactgt tttaatagca caatcgaatt gatgacaggt tttttcttgt agttctgacg
    78301 gtttcatttt cctcacctcc tttcgctagt cgaaaagagg tgtctgcccc ttttcatata
    78361 taccgcgttg aaagtggggt acagcgtaac caaaatcaaa aaaaacttaa aaaatttttt
    78421 tctggcatga aaaaagcccg cacaaaacat atagtctgta cgagcctttg aaactgtatt
    78481 gtatttagtt cttataacaa tgccgttagg gtcaaattga ttgtgtcgag gtatatctaa
    78541 aatattccat aatgacagct cctttacggc actattcttg tttattcaga cagaaaagaa
    78601 attgcaccgt ttttaatttc taagatttcg tcggcttctt ctgccaaatg cttactgtgt
    78661 gtaaccacaa caacacattt tcctaattca tgtgcagtct ttttcagcaa agcaatgatt
    78721 tcatcagcgg tagtttcatc aagatttccc gtcggttcat ctgccaaaag tacatgagcg
    78781 tcgctggcta aagctcttgc aatcgctaca cgctgttgtt gtccaccaga tagttgcaat
    78841 acatttctct gccagtattc ttttccaatg ccgacttctt ccaataattt ttcagcattt
    78901 ccactaccac ctaatttgac attttcaacc gttgtcaaat aatcaatcag attataattt
    78961 tgaaatacca atgagatatt atgctttctg tggtaattca gccctttttt tgtaatgtcc
    79021 tcgccattgc aaaggacagt cccttttacc gctgtgtcta agcctgctaa caacgataag
    79081 agtgttgttt ttcctgcacc actcggaccg acaatggtat agaagatacc ctcctcgaaa
    79141 gtagcagata cattattcaa aatggtttta tctttttttg ttttgtaagc atagcttaca
    79201 ttctttactt ctaacatttt cgtcgtcctc ctaactcatt tccgataaaa tatctttcgg
    79261 gtttctcttt agtattacaa ttccagatac cagaacagaa gccgttatca atacaagaac
    79321 acttgctccg tccagtagat acatttctgg tgtaacctct acgctgatac tctgcacgtc
    79381 ctgctttggt gcaacgtatt ctgtggatac ttttccctca ttattctttt cttcctcctg
    79441 catttgctga acctgctgtg ataccagata atttgcagtt actttggaaa cggcaggagc
    79501 gacagcaaag gataacataa gggaaagaac agcaatcata atcgcttcgc tccaaatttg
    79561 tccgataatt ctaaatttcg gaactccgag agataagaaa ataccgactt cctgcacccg
    79621 atttttcagc cagaaaagga atactaaaac aaggataaca aaacttgcaa cagagattac
    79681 caatatcatc atttcgctta cttttgctaa atcattgaag tttgaggaca tggtttcgga
    79741 atttccgtta ttgtcaatca aatcatattg ctcccagttg atgtctactt tttgcagatt
    79801 ttcttttact tcgtcgtaag cttccacatc ttctactttg aaataggctc tttcatataa
    79861 aggacttgtt tcaccctctg ccttttctgg aaatctcaaa tctgtaaata ttacattttc
    79921 cgaacggtaa gtatcgccct gcataagtgg ggacatcttt tgatccactt gataaattcc
    79981 aacaatctca gcttctgata cctttgaatt tacagtatcg tggtaatcat taaaagaaat
    80041 cttatcgccg attttcagat tattttgctt tgcaagttcc tctgaaatga cacacatatc
    80101 tttatcctct ggggttatca ttcgtccctc tttgatatgc aggtttccag ataaaacatt
    80161 tctgtctagt ttcatatctt tgtttccaat taaacttaca ccgccaacat ctgcattctg
    80221 gtctacatct ttatcttcaa tccttttgaa atttacaggg tttacggctg tgattgctgt
    80281 tgtaagattg taatcagcaa ttccttttgt ttttgccagt ttctcaatat cctttatatc
    80341 tagggtttca aattcatttg ttgaccaccc ctgccaattt tctacaccat taacgactac
    80401 tttcttttga tgataccctc caaaactacc ttccttatta ccaatctttt ctgagtattc
    80461 acgaagtcgt tctgttcggt actctgcatt tctttctaaa agaaagcctg cacctatggc
    80521 ttgtctggtt ttgtcctgca cctcaatact ggcatttttg ctcgccacac ctgcaagaag
    80581 cagggtactg attgcaaaaa caatcaacaa taagagaata ctttttacgg gctttctgaa
    80641 cacagaacgc cttgccaatc caaaaaaatt catgtactat ccctccattt tcgctaatat
    80701 atcttttggg tttgctcgta atatcggaag aatggagcaa cacaatgcta ccaaaataac
    80761 tgcaccgcct aaaagaaaca acattccaat atcttgtatc tgcaacacca ctttcagatt
    80821 ttctgttacg ctttctgaac tggtaatgat gttttgcaaa acgcccgaga acaatttacc
    80881 aatggctgtt gctcctaaaa ccgaaagcgt aaatacactc cctgcttcta ataaagtttg
    80941 caggaaaatt tcaatttttg tcttaccgag gctcataaag attgccacct ctttttgcct
    81001 tgtccgcatc cacatacata acagcaggga aacaacgact gtaccagtta ctaatgtaag
    81061 tactagcata agatttgcca ccttactgat ttgctctaat ggggcagaca tctgttgata
    81121 aagggtatca gacgtgctaa gtgctacatc atttccgaat attttttgca ggctggtttc
    81181 cagcacatct aatttttctg gtctttttga gtaaatgcag attttttcaa attcagcttc
    81241 tttgaacaat tctttataag tactgttgtc aataaagatt tgattttcta ttcgattgac
    81301 tgcggtagtt tctgacggct ggtctttttc cgcatttcct gcggacatga aaattccaat
    81361 aatctgaaca gatacttttg ttccgttttc tgtacttagt tcaatcgtat ctccaacctt
    81421 tagcccattc tgatttgcaa ggttcgtatt gataacagca cctttttttt catgtttgat
    81481 ataatcgcca gaagctaagc ggtactgcat ttctgaaaag ggactgtcct tttccaaatc
    81541 atcataggaa agcagtgcta ttttcaaatt ttcctcattc gtagaagtat tgagcgtaac
    81601 gggagcaaaa ttattcggaa atacctcttg tctaccaatg cggttgatag acgaaacatc
    81661 ttctagcgtt tcaatcttgt ttacttcatt ctctgttatc ttgctgtcct tacttgtaat
    81721 ttcagccaca atcttagagt ttgtcttttc ctgcatggct tgtttggact catttgtagt
    81781 ccttaaaatc atgcttgtac ctaaaatcat actgtttaca agtatcaaaa caatcaacag
    81841 aagaatggtt tttccttttt ttcgctgtaa atagcgaaaa ccaagttgat aaaacttcat
    81901 acttcacacc tctattccca acgagctacg acaacctttg ttgcattgaa atgatttgtg
    81961 tctgcaaact ctccatagag atatacttca gattgctttt tcacatcgga tatagaaccc
    82021 gttgttacat ttgtaacacc agactgttta tttagtgtcg caacaacaaa ttcacaatct
    82081 gggttatagg ttacagaaac agcattgtct ttattttcca atcccgctgc ttccgatttt
    82141 attccagctc ccccctcaat ttcttttgct tgacttacgg aacaaccatt gtctgtaaat
    82201 tccaaaacac ttcctatcaa attagcagaa tctaatatgt cgtttccttt attttctgaa
    82261 gaaccatttg cattttcttc attcgtatta gaattgacaa taggattaga cgtatctggt
    82321 ttctcatctg gacttgcacc acaccccgtc aatgcacaga tacataatcc aactgctatg
    82381 aatttactga tgtttgtttt tttcattttt gtattccacc tttcttgttc gatatgcccc
    82441 tattgtaaaa gcaaaccatt ctaaaaatcc tgtaaaaaag taagaaaatc atcatcattt
    82501 tttagaggat ttttacagac ttttctgtta tactgtctat aattcaaact tcttggactg
    82561 cttatgtcca agatgatata tagaaaagga ttgatacatt atgaaaatac ttcttctgga
    82621 agatgattta gaattatgta aaaatataaa aatttcgctg gaaaaagaaa actatatggt
    82681 tgattgttgc aatgacgggg aaactgctat gctgtatgcc ttaaatacag actatgctta
    82741 tgaccttgcc attgtagacc gtatgttacc gattattgac ggattaacaa tcataaaatc
    82801 tatgcgtaga aaaggaatat ctattccaat cctcatcatt actgccatga gtacccttga
    82861 taatcgggtt gagggtttag acggcggtgc tgatgattat ttagtaaaac catttcatat
    82921 caaagaattg cttgcaaggg ttcgggcatt gacaaggcga cctgccaata tccagttatc
    82981 gcctaaatta caatatggag atttaacttt cgataaagac agccgaacct tatctacacc
    83041 cgtcaattct attttattaa cttcaaagga aaccgaattg acttttgtat ttatgcagaa
    83101 cccagaaacg ctattttctc gtgaacagct aatccttaaa atctggggca gttcttccga
    83161 ggtagaaact ggcaatgtag acagctacat ttcttttctg cgaaaacgcc tgaaagagtt
    83221 aaaaagttcc tgtaaaataa caacggtcta cggtgcaggg tacaaactgg agaaagaaac
    83281 atgttaaata atttataccg aaaacttcat attctgtttg caagttctgt tatgctgatt
    83341 attacccttg tgatttcctt tgtcgttgcg aacacagttc atacagagaa aatcaacgaa
    83401 agcaccttgt ttcaaagatt gacaaccttg ctgatttatc aagtggaaag tgcttcttcg
    83461 gatatggaca aagcactcaa aacctacgaa gaaagttatc atattttttc tttaattact
    83521 gatacaaggg ggaataccat ttatcagagt gatttcccat ttccaacttc tgcggataat
    83581 ctgttgcatg atgtagaaat gcagatttct acacaaccat tatcacaaac agaaagcaac
    83641 acaacttcac aaggcggttt tttggaaata agaggaacac atcacgatac ttattttgtt
    83701 attcctgcta caattaggac agcaaatgat accgtgtatc atgcaacctt tctttatcag
    83761 acagccagtt tgacggatat tttacaaaag acattgccta tatatcttct tatctggttt
    83821 ttggcttgta tcgttgttat cgtgctaacc cgttatctgc tgaaaaagtc gtttgctcca
    83881 acggaacgaa tactgcaaag ccaaaaagat tttgttgcaa cagcgtccca tgaattaaaa
    83941 tctccacttg ctgttatgat ttctaacacg gatatgcttc ttgataatgt ttccttaaac
    84001 gagcaggcaa agcaagccgt acagaccgta gattttgaat gtatgcggtt atcccgttta
    84061 gtcaaagata tgttgctttt ggcttcttcc gacgctaaaa catggacatt gcataaaagc
    84121 acaatcaatg tagatacctt gctcattacg ttatatgaaa cctacgaacc cgtctgcatg
    84181 aagcagaatt taaaactaaa actgcattta tccgaggaaa gttatcctgc catgcttacc
    84241 gacaaagacc gattatttca aatcttgtgt gtctttatgg ataatgccat tcaacattcc
    84301 aagaataatt ctttgataga gatagaagta atcgccaccg aaaaaaatat tgctttttct
    84361 gtggtagacc acgggcaagg catttctgat gaagataagc agtatatctt tgaccgattt
    84421 tatagtggcg acaagtccca tacgaacaaa tcgaattttg gactgggact aagtattgcc
    84481 aaagaattaa cccaaatgct gaacggtgct atcactatca atgatactgc tggtggaggt
    84541 gctactttta ctgttaaatt tcctctgaaa tagattaagg cttgcagatc atacactatg
    84601 tatggagcaa gccttttttc aaatctttgt ctttttggta atcttgtaaa tatattcttc
    84661 tggggtaggg cgtttattac caaaatattt tttgaaattc gcctgcactt ctggggcggt
    84721 gctattcata gcttcatcaa tcgtcgcttc aatatctgcc cgaacatcag ccaatgatac
    84781 accgccagct tttgcaccag ctttcaacgc tttttttata tctcgctttt ttagtcctat
    84841 cataataacc tttcttatca taattgcaaa tttataaatt cattagtatt aaaactgaaa
    84901 ttcaaataca ttactaaaat cattgttcaa gacataataa actttatttt tttctgtaga
    84961 atatacaaat gaaaccctag ttgcccacaa gtctttttga gaaacagatt ttaatacttt
    85021 aaatgcgtca tttactgaaa aatctttatc atatcctgcc aataactctt tagccacttc
    85081 gtatcttgta tccccagaaa caatgtacgg ctttgttata tctggtttta gaatagaata
    85141 atttgtaata agtgaaaaat tttcttgttc atatctatac ccaattccgg gttcaataat
    85201 taaaactcgt ccttttttat cagaaagcat agcttgcata gtagcatctg gtgcataaat
    85261 aatttttttc tttttaacaa tgtccaaggc tttatcaaaa gaaatctctg ccttaatgaa
    85321 tttttctgtt aattcagata ttgtaataca atcctcgctt tctatatacc ttgcattttc
    85381 attaccatga acataaagaa gtgttcctac attaccattt ttatttatcc catgaaatga
    85441 atgatacata ccgtcaggca ttttaatacc aatataaaat ctattttctt cggtaattac
    85501 agtatgatcc catacagaaa ggtcaatatc aaaattaaaa ccaacaattt tatctatacc
    85561 attgtaaaca aatcttgtac acatataatc actcctcaaa atactacttc aaatagttat
    85621 ttaactaatt caattagtat tttaaaatgt ttttgtagga aagtcaataa ataatcataa
    85681 ttttctaatt gtgttattga ctacactaat tcaattagct agaattgtgt ttgtatgata
    85741 ttttgaatga ggtgcataac tatgaaaacc actaaagaag cagtaataaa agcaacatca
    85801 gacttagcag atgaaaaagg attaaataac gtttcgttaa aagctgttgc tcaaaaatta
    85861 aacattcgta caccatcttt atataatcac atagaaagtt tagataatct tcttttagaa
    85921 gttgctcata atggtatgcg tgacatgaat gaaagaatga tgaaaattgc cgttggaaaa
    85981 atagggaaag aagcaattaa gttagtttct atcgaatacc taaactatat gattgaacac
    86041 cccggagttt atgaaacaat tcaatgggct gtgtggcacg gaacagagga aacagcaacc
    86101 atttttaaca actatctttc attattaact actcttatcc aatcgtgcag tcttaacaaa
    86161 gacaaaacac ttgaaatatt aaatatgctt actggaataa ttcacggtta tacaactttg
    86221 caattaggaa acgctttttc tgcctcagat aaagttagat ttgaattagc tgaagcgata
    86281 gatactttat tagtcgggat tttccagaag tataaataat atatttaggc ttgcaaatca
    86341 atacagaact gcaagccttt ttcttttatc caacaatctt ccagttgcta tccttatgta
    86401 gtgcaagttc atactgcgat acttgtgttg cctttgtctg attatcaagg aattttacat
    86461 caaccttaac tttcacattg tccccgtcct ttgtaaagat agggtttacc agttcagaat
    86521 aaaggtagtc cctgccgata ggttcaatca cattccccga tacatagtag gcaagctctt
    86581 tttctgtggc tgttggatag agcttaaaga atgtttccaa aaatgcggta gcgtcattga
    86641 cagtatcagc gtctacgctt gcgtctgctt ctggtgtctt aggctcatag tctgattttt
    86701 cgattgctgg tgcaagggta gggttctgaa cgattaccat atctccgtca gcgtccacat
    86761 ggactttcac ggtataggtt gccttgacat ttcttgcctg ttctccctct tttatctgct
    86821 gatctacttc gtaggtagca gaaaaagtgt ccgttcccga ctgttcaata ctccatacaa
    86881 tcacatctgt aactgtggaa ctggttggta tatccattct gattgtatca acattcaagt
    86941 cctgcaattc ctttgtcaga taaccgttga ttgcctgcgt ccttgcttca atcgcttctt
    87001 tgctgttgct ccatgtgtaa taggacttcg caaagttctt cacgaaattt tctatcccgt
    87061 tggtgtcctg caagcgaagc tcaatgattt ctttttcatg ggtcgtgtgc tggtcgatag
    87121 cggtaaaatt cttatacact ccaaagctca cgcttgcgat aagcaccacc cacaacgcaa
    87181 tcacggtttt cttatgtgtg cctaccttga cagtacgcac ctttttttct tttggttctt
    87241 tgatagtttc tgtctgtttc ttattcttct taaacatatt ttcaagtcct ttctattgtt
    87301 ttactcgtcc tgcaccgatt aagtgctgtt gccagtaact actacttagg tctgcatatc
    87361 ctatcgggtc gcctgcatgg tacatctggt tatttcctac ataaataccg acgtgagtta
    87421 catacgaacc agcgttataa gtggaatgga aaaataccaa gtccccagcc tttgcctgcg
    87481 aaagcggaag atgttgggtt gcgtcatatt gtgcttgtgc tgttctcggt aaggagatac
    87541 cagcttttcc ataacaccat tgcacaagtc cactacaatc aaaggaagtg ttcgggttac
    87601 tgccaccata tacatacttc cagccttgat atttcaacgc ttcattcatt accttttgtg
    87661 ccagttctcc agatacctgc ggaacagtta aatactgatt gactaattcc gcatagaaca
    87721 tatttccata gccataccgc cagcccccgt tcttcgcaac agctatcggg ttggtgtagg
    87781 ttactttctt tccacccgac ttctcacggg cgaagctctc tgcaagatta aaagtgtgtt
    87841 tctttccttt tcctgccaca tatcccacat agccaccgcc ataattataa gactgtatcg
    87901 ctacattcaa atcgtcgata ccttgatttt tgcaggaaga aagcagggac gcaaaatact
    87961 tacacccctg cttgattgag ctttccgtat ctaaggaatt aggcggtaaa ccaagacttt
    88021 ccgaactctg cataacatct tctgccgtac cgccactttc tacttgaatg atagccaata
    88081 gcacattgac atactcggag ataccgtatt ctctggcgta tttttctacc ataggctgat
    88141 gtttcaagac ttctgcggat aagttcatac ctgtaatgcc agaagaaaaa ttgctattct
    88201 cgtcgtcgct gtccgcacta atcaacaccc caaagaaaag taccagcgaa aagaggatag
    88261 gaaacagact gccgataaga gcgatatgtt tcagtttcat tttttcttct gtcctttctt
    88321 catcacaagg ttacgggttt tctctgtggt ctgctggttc ttctggacgc tctgtgtctg
    88381 atgaaccttt gtcctgcggt ctttggtgta attctggcgt gtttcctgcg ataccacttt
    88441 ttctacattc tgcctatgta ctggctgtgc agactgggtc gctttcctat cagaagcacc
    88501 agaagataac ggacgctctt tgataacatt tgtcttgact ggctcacttg cttttgaagt
    88561 ggtcgctgtg gcagggcgtt tgacttcctg cgttttttca gcactcggct ttggaatgat
    88621 tgaagctgtg gctggtcgct catggggacg ggtagctccc gttgtcgctg atccgtcagc
    88681 ctttcgctgt acctgccttg cttcttgtgc cttttgaagc tccatacgct tgtcagcgat
    88741 atttttctta tgctgttcct gcttttccaa tcgtcccgtc tgtctggatt gctgttcctg
    88801 caccatgcca cgcttgaagt cggacacgct ggactttgcc ttttcctttg cggaatacac
    88861 cgcataagcg gtctgtgtcg gcatatcctt gatattctct ttgacagcat ttgccttgtc
    88921 tttcacttta tttctcgtat ctaagacagc acccaccttt gagcctgcac gctgtcccat
    88981 gctggaagtg gtattgcccc gactgtcttt tgtagctgtg ttccttgtcg gttttctgtt
    89041 tgaaatcgtg ttacctgcca ccgcaccagc aacaccgcca gccgtaaccg caccagcaag
    89101 ccgtctttcc atacgcctag ccctatgtcg cataaacaga tacggtctgc ggaatatgcg
    89161 acgtcccatg ctttgactat cgccagcgtt caaagagaac atattcatta agtcgcctaa
    89221 cttgataaag atacctgcaa aacacactat ctgtaagaac gccaccataa aaaacgggta
    89281 ctctttggag atgttataaa acatactgga aatactgaac gccaccgtta caatgagcgt
    89341 aattcctgcc cgtgtcatta tggtattaaa taccttcacg attgcctgct ttgccagatt
    89401 ttcttgactg ggtatcatgg aaagaagaaa actgataggt aaaaacatag cgaagataat
    89461 aaaaagtatc tggcttaaca tcattatccc tgtcagtaag aatacaaaga ttgtgatacc
    89521 tatattaaaa atgaatagga agaacaccat gcctaaacgg ttcacgacct gcggtatcgt
    89581 cagattgttg ttgtcattgt cctcgatttc tgttttcacg acttcttctc tggttttccc
    89641 gtcctcgtcc tctgggcttg ccgatacgag agcttcgaca cggtctgttc cgattttctc
    89701 tgcgttgctg ttaccgaatt gtaagagtag ccacggctgt tccacttgaa tagaaaatag
    89761 gctgtcccgt atcaagtcca cgctgtcctt gccctcgctg tcagagttag ggagcatgat
    89821 ttttgttccc aagtcaagtg aagcggtact aatatcactt gaaaattcat ttatcttctt
    89881 gatgtagtcg ggagcatagg cgataaacga agcggacagt acgaacacca caagaaaatt
    89941 gataaccgct tgaaccgctt tgctggtttc tctttttatc agtcccgtat aggcaacata
    90001 aataccaatg attaaaatta tcagtaatag agaacccaca taaaatcccg tactcccgaa
    90061 gccattctcg gtaacacctg caagggtctg tatgcttttt ccaatactgt ctgccatatc
    90121 gttaataaaa tcaagtttat aggcttcctg caccacatag cccgttgcat tgcttaaata
    90181 aaggcttatc gtccagacaa agttggtaat acagtaaagc ccgtactgca ccgattttcc
    90241 gataccgtcc agccagttcc acggaagcca cgaccagcta ttatccacat aaaaatcaag
    90301 ctggtagttg gaaaggggat attttgaata tagattttct gcgtttatgg tatcgtccac
    90361 aagccccgtc gcatgagcca ccgtccccag aagtgaaagc aggataaggg agagtgccac
    90421 cacgaacaga gccattttga gaaagtgaaa aatcttcttt tttgtgaacg caccttttat
    90481 cctttctttc atcactccac ctcatttctc tgtacgggcg gtctggtatc aaaggcgtgt
    90541 agcagttctt caaaaactgg gtgtatctgc actacaccga cacgcccgta taagtcctgc
    90601 aataagcatt gtccgttctc caaatcacgc aagcgtttct ggttgttttc gtcgtccttg
    90661 tcgataccga aaaattctaa ggtctgcttt atctcgccca agtcggtact acgaaaggca
    90721 aacttcaagc cgatattgtt tttcagactt tcctttgcca cgtccccaga agattgtgta
    90781 acgaaataaa cgcctgcctg catagctcgt ccagcacgaa ccagcttgtt tgataaggtt
    90841 tcgccttgtg ccacatttaa gaacgcccac gcttcgtcaa ggtctacaat cttaaaaata
    90901 cttctatccg aatggataaa atcaagggca aaggtactaa tcacaatcag catagacacc
    90961 gacaataatt caatggtcgt gtattcctca aaagtggtat ctttatctgg caatactaag
    91021 tccgctactt gaatgatatt gagctggtta tccaaactga tagcattttc tactgtaccg
    91081 tccgaaaaca gcaggtgtgc aaagtcgtag tccgtgaagc tgtcgatatg gtctgcgata
    91141 tttcttgata tgagcgtatc ttcacggcgt agctcgtcta tcacatggag caagccccga
    91201 ctgtcgctct gggtaacgga acgcaccgct tttcgtaaca cggggaattt ttcgccgtcc
    91261 ctagaggaaa tacccgtaag gaatgttaag atatcgattg ccagactttc agcgtctttt
    91321 acattcttca taatcacgaa tgggtcaaga agacctgcat tgtctttatc gctggttaag
    91381 tttacgatat tgatttcatg ggctatctct gggagcgttt ctttccagtt gccacgctct
    91441 gattttgggt ctaagataac cgcttgtccc ccaaagagaa cagagtagta cacaagaaga
    91501 ttgttgcaga acgacttccc accgccaagc gaaccaacaa aagcagaagc aagagcattt
    91561 gtaactgtgc cttttacgcc ctgcgaagct aaagacggtt gcaggtacac atttcttccc
    91621 gtatcaacgg aatagcccat atagataccc gtagtttctc ctaactgctg ggtcgctcca
    91681 aagccaagcc cagctaaaaa atctgatttt acatactgca catagtcatt gatatatcgc
    91741 ttgccggcag gaagaaattc agaatgaagc cccagcatat ccccagcagg acgcaccagc
    91801 tttacattga ggtcgtcgta aaagtctttg acttcatcac aacggcgttt cagctcgtca
    91861 agatcgggtg cagacacccg tatcacgtag cttaacttat acatactttc tttgctctgg
    91921 tctaagtctg tttccagctc gtccacgctg tctaatgcgt ccaccacatt tgagctggtt
    91981 tcacttcctg cttgataagc gtgattgtca aggtctttca attccttttt cttgttgcgg
    92041 acggttgtta atgcttttcg attttccatg atttctacat tcatagaagt atcaacgggg
    92101 aatgtgaatt gctgttgctg gaaatagaag atttcacttg acggaaaatc aagctcgccg
    92161 acaatcgcat tgacggtaaa ataggacaca tagctttcct tgtcctcatg ttccaatcgt
    92221 aaataccgct ggctttcctc aatcacacac cttgtcgggc ggataaggtc gtagtatttt
    92281 atcagcgttt ctttctgcaa tttcttcttt ggtagctggt actcataatc ttcataggca
    92341 ataccgtccc tgccgtaaag atgttccatg agatacccaa aatcattgat ttccaagcga
    92401 cgcaccttaa agcgacggga gattttattt tccagtaact tttccatttt catgtaacgg
    92461 ttgatttcat cattcggcat ggaaacaaaa tcattcatca gcgtatggtt cacttcatgg
    92521 agaaattccg tgaacgtcag ccacgccgat tttttgatgt tcttcagatt gagctgttct
    92581 tccgtaacca tgagcttaaa gccaagaaaa aagcggtagt ccacttgatt gtccccaatc
    92641 atagatacta acgcttcggt ctgttcgtct atcttctgat aggcaacttc ctttaatttt
    92701 ccagttacca gcttctttga ctgttcctgc tgacttcgga ttgagctttc tgtggcaatc
    92761 tgcaacgcat gaattttacc ctcacgggac tgtacgatta gctgtcggaa actgtcatgc
    92821 acgataaatt tctgctctgc ggatagaaaa gaatagttat acggtatcag ctcatagtaa
    92881 gcgaacacct cattgtcctt gttccagaca aggttattgt caatatattt tatcgggaac
    92941 atagttcaca ctccttactg ccgtgattgt ttcattcaag gtctgcttat gcagttttac
    93001 ggcttttcct gcataagtga ttttaggtcg cagagcatag gttatctgtg atttcaaaaa
    93061 gctgtacggc ttctttccgt caaaggtttt ctgcgacata aaccaagtga gagcaacggg
    93121 aataccgaag tatttgagaa atgctccctc aatcatggaa agtgggggaa tatccccaaa
    93181 cagaatgatg ataaattccg taatcacaaa ccatgtaatc tgtgtaaaag taacgggaaa
    93241 gggtaagtta aagtcattga ttgcatacaa gactttttcc acgttccaga tacccgtata
    93301 agatttaatc tttttcaagt tctttcagct cctttcaaaa tagaaaagga cagccatgtt
    93361 tcagactgtc ccttaaaaga gaaatacgct gtcagtagca acaatgcttg tcgctgatct
    93421 tccagcgtta atatggtatc tcgcacatac ctcggcttgt ttcaataaag caaccgccca
    93481 tatccaaatc tcgcccgtag gcttcatagt caatgtaatt ctgtaagctg ggtggaatat
    93541 ctcctagtgc ctgcaattcg tctatgtagt agtaggcaac gtctgtcatg gtttcacagt
    93601 cgggataata ataaatatcg tccttgtgtt ccacgacttc ttccagcgtc ccatagtagc
    93661 tgataaattc gtccagacat tctacgatat agtcgggaag ttcctctatc atttcataca
    93721 tctcgttgag ttcttcaatg gaaacatact cgccaatcgc aatggggaag ttgtcggtat
    93781 catggatagc gtattcctca tactgttcat tcaagccgat tttttctttc acatcttcct
    93841 cgtcaatggg gaacgtgaac caagcaccga ctaaatagcc ctcattgtat ttgccaagat
    93901 tagcaatgta aaccgccata tcatcaatca taagcaccac ctcatttcct actctggcag
    93961 ttcaaagata ccgtgttctg ttactaaaaa tttcccgtgt tcctgcaagt gagaagcgta
    94021 ggcttcaaag tcaaaatagt attcttgaca gtcctcggat aaatgcttaa atgtcgggtc
    94081 gttcatcagc ttttgctttg caacatctat catgcttttg cagtcgggat aaaccgtaat
    94141 cacgttcctg caaatataaa gtgcttctaa attttcatat acggtaagaa gtgatacata
    94201 ttcttcctgc atatcacttg aaagctggcg gtacataaaa tctaattcgt tgagctgata
    94261 cacgcttgta tgttcgtgga cttcatcagc aaagggcagt accttttcga taatgcggta
    94321 atccccactt tctgcaccga cacctaactt ttcttcaaac tcggcaacat ctatcggcag
    94381 gtcaaaccag tatgatttcg tttcttcgcc agttgttcct ctcgtttcca ccagcaccct
    94441 tgtttcctgc attgttcctc acgtcctttc tgttgtttca tcacatcttt taaggtctgg
    94501 tacgacatac caaacacata ctttgaaaaa tcttctaact gtctttcttc atagtcagca
    94561 gggttcagcc gtttcatttc atgccacacc ttacgcttgt aagagggcag gtcggaaatg
    94621 tattcacagc cgacgtttgc ctgcatatcc ttaaaaatat cgttcatttc atcactccaa
    94681 tctgaaattt aggtatgaaa aaagcaggag accttttcag atttcctgct cagtagagtt
    94741 gtgaagatgt tattgttgtt atttaatttc aatgttcgtc atagttacta acccaagacg
    94801 aactaaaata gtttgtacga tacgatacca aaaaacacct agaattagga gtaaagcata
    94861 taaaataatt gacgcttgta aatattgtct gccaaagtga ataagaataa gcagtggaga
    94921 cattaatatt acaaagaata taatgcttgt aattattttt tttatgtttt ttctatctgc
    94981 taaatcaaat tcagctccac aagaacattt gttaggtatt cctcctttta tttgagcacc
    95041 acagttcatg caatatagtt tcttcattct aatcacctct acaacctcta attcgtcgtt
    95101 ttcttcatat ccacattata acattcgcat atcaacacta caataaaatt ttatgctccg
    95161 ataatcttat tgaacagctc taacagtaca ttatttcatc actccaatct gaaattttgg
    95221 taagaaaaaa gcagtcaatc ctaagactaa ctgctttgtg tgtagggata tgaaattgta
    95281 aaactggaat tttttctttg aaagctctta aacaaatgaa gcataaataa cataaatttc
    95341 tgcaatcaaa acaattccaa gaactccatc tatcatcaaa ttatactgta tatctgtcaa
    95401 aaaagttttt gaatgtgtta agaaatactt tattttttct tttccagtta aaatcgtaat
    95461 tataagtaat aaaataggaa acaaaaaaat ctctatctta tttccaaaat catctgctat
    95521 tccatttgca aaatgcacag gaataatttg aggtaagaaa agaacgccta ctaacgctaa
    95581 taaaatacca ataccgcaaa ttccccatgt taattttctg cttcctacaa gtttcataaa
    95641 aatgccttct ttctgctaaa ttataatgtt ttgcttttca tatccacatt atagcactca
    95701 catatcatca ccacaataaa attttatgct ccgataatct tattgaacag ctctaacagt
    95761 acatctttca caccgccagc attgaacacc aaaccgacag caattaaggc aactaccaag
    95821 aagccgataa gtttggaaaa ctcacgcttg aaccctaagt aaataccgat aaccacaatc
    95881 gccataagca ctaagctctg tgc
//
LOCUS       DAEPUT010000004        91799 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.004, whole genome shotgun sequence.
ACCESSION   DAEPUT010000004 DAEPUT010000000
VERSION     DAEPUT010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 91799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91799
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.004"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            119..310
                     /locus_tag="KRL22_000366"
     CDS             119..310
                     /locus_tag="KRL22_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBH1270890.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            465..1874
                     /locus_tag="KRL22_000367"
     CDS             465..1874
                     /locus_tag="KRL22_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1270891.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTVDDFSSLETALNNIVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            2005..2694
                     /locus_tag="KRL22_000368"
     CDS             2005..2694
                     /locus_tag="KRL22_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBH1270892.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKSMER"
     gene            2697..3632
                     /locus_tag="KRL22_000369"
     CDS             2697..3632
                     /locus_tag="KRL22_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBH1270893.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3629..4522
                     /locus_tag="KRL22_000370"
     CDS             3629..4522
                     /locus_tag="KRL22_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBH1270894.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4600..5346
                     /locus_tag="KRL22_000371"
     CDS             4600..5346
                     /locus_tag="KRL22_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBH1270895.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5347..6180
                     /gene="rsmI"
                     /locus_tag="KRL22_000372"
     CDS             5347..6180
                     /gene="rsmI"
                     /locus_tag="KRL22_000372"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBH1270896.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRTLKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6203..6907
                     /locus_tag="KRL22_000373"
     CDS             6203..6907
                     /locus_tag="KRL22_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBH1270897.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGINLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7095..7523)
                     /locus_tag="KRL22_000374"
     CDS             complement(7095..7523)
                     /locus_tag="KRL22_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH1270898.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7560..8990)
                     /locus_tag="KRL22_000375"
     CDS             complement(7560..8990)
                     /locus_tag="KRL22_000375"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBH1270899.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9122..9706
                     /locus_tag="KRL22_000376"
     CDS             9122..9706
                     /locus_tag="KRL22_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HBH1270900.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9722..10243
                     /locus_tag="KRL22_000377"
     CDS             9722..10243
                     /locus_tag="KRL22_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HBH1270901.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10309..10555
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10639..12576
                     /gene="metG"
                     /locus_tag="KRL22_000378"
     CDS             10639..12576
                     /gene="metG"
                     /locus_tag="KRL22_000378"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBH1270902.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTNFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12606..13376
                     /locus_tag="KRL22_000379"
     CDS             12606..13376
                     /locus_tag="KRL22_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBH1270903.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13713..14144
                     /gene="phnG"
                     /locus_tag="KRL22_000380"
     CDS             13713..14144
                     /gene="phnG"
                     /locus_tag="KRL22_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBH1270904.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14159..14734
                     /gene="phnH"
                     /locus_tag="KRL22_000381"
     CDS             14159..14734
                     /gene="phnH"
                     /locus_tag="KRL22_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBH1270905.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSTINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14737..15822
                     /locus_tag="KRL22_000382"
     CDS             14737..15822
                     /locus_tag="KRL22_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HBH1270906.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRDFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15842..16711
                     /locus_tag="KRL22_000383"
     CDS             15842..16711
                     /locus_tag="KRL22_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBH1270907.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGNDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTSEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16704..17570
                     /locus_tag="KRL22_000384"
     CDS             16704..17570
                     /locus_tag="KRL22_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1270908.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17611..18324
                     /locus_tag="KRL22_000385"
     CDS             17611..18324
                     /locus_tag="KRL22_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1270909.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMAKGTISESGVA"
     gene            18325..19494
                     /locus_tag="KRL22_000386"
     CDS             18325..19494
                     /locus_tag="KRL22_000386"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBH1270910.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19498..20334
                     /locus_tag="KRL22_000387"
     CDS             19498..20334
                     /locus_tag="KRL22_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH1270911.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20335..21330
                     /locus_tag="KRL22_000388"
     CDS             20335..21330
                     /locus_tag="KRL22_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1270912.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21348..23036
                     /locus_tag="KRL22_000389"
     CDS             21348..23036
                     /locus_tag="KRL22_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH1270913.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMKHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23048..24115
                     /locus_tag="KRL22_000390"
     CDS             23048..24115
                     /locus_tag="KRL22_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1270914.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLELYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24601..24717
                     /locus_tag="KRL22_000391"
     CDS             24601..24717
                     /locus_tag="KRL22_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein"
                     /protein_id="HBH1270915.1"
                     /translation="MDDDINMIAIRPEDIRVEFNRDFKEIIDLKLRPYRYKN"
     gene            24881..25948
                     /locus_tag="KRL22_000392"
     CDS             24881..25948
                     /locus_tag="KRL22_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1270916.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PSSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26140..26670
                     /gene="rnmV"
                     /locus_tag="KRL22_000393"
     CDS             26140..26670
                     /gene="rnmV"
                     /locus_tag="KRL22_000393"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBH1270917.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            26841..27710
                     /gene="rsmA"
                     /locus_tag="KRL22_000394"
     CDS             26841..27710
                     /gene="rsmA"
                     /locus_tag="KRL22_000394"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBH1270918.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            27776..29050
                     /locus_tag="KRL22_000395"
     CDS             27776..29050
                     /locus_tag="KRL22_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270919.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDSDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEENEESDRDEVSEE
                     EYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSGDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANG
                     VSQGESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTM
                     PYLGYLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGS
                     TGFLRYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29201..30316
                     /locus_tag="KRL22_000396"
     CDS             29201..30316
                     /locus_tag="KRL22_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1270920.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIIAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30502..31398
                     /locus_tag="KRL22_000397"
     CDS             30502..31398
                     /locus_tag="KRL22_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH1270921.1"
                     /translation="METRYEEANKITIQSILWNIVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31468..32265
                     /locus_tag="KRL22_000398"
     CDS             31468..32265
                     /locus_tag="KRL22_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270922.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(32320..33672)
                     /locus_tag="KRL22_000399"
     CDS             complement(32320..33672)
                     /locus_tag="KRL22_000399"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBH1270923.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            33891..34769
                     /gene="purR"
                     /locus_tag="KRL22_000400"
     CDS             33891..34769
                     /gene="purR"
                     /locus_tag="KRL22_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBH1270924.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            34925..35203
                     /gene="spoVG"
                     /locus_tag="KRL22_000401"
     CDS             34925..35203
                     /gene="spoVG"
                     /locus_tag="KRL22_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HBH1270925.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35416..36795
                     /gene="glmU"
                     /locus_tag="KRL22_000402"
     CDS             35416..36795
                     /gene="glmU"
                     /locus_tag="KRL22_000402"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBH1270926.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            36890..37840
                     /locus_tag="KRL22_000403"
     CDS             36890..37840
                     /locus_tag="KRL22_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HBH1270927.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      38678..38763
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            38925..39437
                     /locus_tag="KRL22_000404"
     CDS             38925..39437
                     /locus_tag="KRL22_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBH1270928.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSIKSAALSYYSDTNKMPATTSNPVDLENLKTYMESLPDKADIGGEYQLLLVG
                     NKLVLQINDATLTGAQSTKLLSDLGNDKIYKTIGSDDKLTDLLTTNEKLDNKVLYLVL
                     IDNAEMDSTK"
     gene            39589..41265
                     /locus_tag="KRL22_000405"
     CDS             39589..41265
                     /locus_tag="KRL22_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH1270929.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            41277..42485
                     /locus_tag="KRL22_000406"
     CDS             41277..42485
                     /locus_tag="KRL22_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH1270930.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            42500..44212
                     /locus_tag="KRL22_000407"
     CDS             42500..44212
                     /locus_tag="KRL22_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HBH1270931.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            44205..45113
                     /gene="pilO"
                     /locus_tag="KRL22_000408"
     CDS             44205..45113
                     /gene="pilO"
                     /locus_tag="KRL22_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HBH1270932.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            45140..45706
                     /locus_tag="KRL22_000409"
     CDS             45140..45706
                     /locus_tag="KRL22_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1270933.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            45743..46270
                     /locus_tag="KRL22_000410"
     CDS             45743..46270
                     /locus_tag="KRL22_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1270934.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            46291..47829
                     /locus_tag="KRL22_000411"
     CDS             46291..47829
                     /locus_tag="KRL22_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270935.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSINKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILEEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLENLLEILPDQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIINFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            47929..49011
                     /locus_tag="KRL22_000412"
     CDS             47929..49011
                     /locus_tag="KRL22_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBH1270936.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            48992..49774
                     /locus_tag="KRL22_000413"
     CDS             48992..49774
                     /locus_tag="KRL22_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH1270937.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGLYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILSGKQLLELYFSMVI"
     gene            49876..50526
                     /locus_tag="KRL22_000414"
     CDS             49876..50526
                     /locus_tag="KRL22_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH1270938.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLAFFNI
                     AQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            50540..51100
                     /locus_tag="KRL22_000415"
     CDS             50540..51100
                     /locus_tag="KRL22_000415"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBH1270939.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            51117..54503
                     /gene="mfd"
                     /locus_tag="KRL22_000416"
     CDS             51117..54503
                     /gene="mfd"
                     /locus_tag="KRL22_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBH1270940.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGAENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            54534..55529
                     /locus_tag="KRL22_000417"
     CDS             54534..55529
                     /locus_tag="KRL22_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1270941.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            55653..56192
                     /gene="spoVT"
                     /locus_tag="KRL22_000418"
     CDS             55653..56192
                     /gene="spoVT"
                     /locus_tag="KRL22_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HBH1270942.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            56312..57925
                     /locus_tag="KRL22_000419"
     CDS             56312..57925
                     /locus_tag="KRL22_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH1270943.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            58032..59480
                     /gene="mazG"
                     /locus_tag="KRL22_000420"
     CDS             58032..59480
                     /gene="mazG"
                     /locus_tag="KRL22_000420"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBH1270944.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            59569..59847
                     /locus_tag="KRL22_000421"
     CDS             59569..59847
                     /locus_tag="KRL22_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBH1270945.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            59919..60161
                     /locus_tag="KRL22_000422"
     CDS             59919..60161
                     /locus_tag="KRL22_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBH1270946.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            60223..60477
                     /locus_tag="KRL22_000423"
     CDS             60223..60477
                     /locus_tag="KRL22_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HBH1270947.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            60478..61011
                     /locus_tag="KRL22_000424"
     CDS             60478..61011
                     /locus_tag="KRL22_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270948.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            61017..61301
                     /locus_tag="KRL22_000425"
     CDS             61017..61301
                     /locus_tag="KRL22_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBH1270949.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            61414..62334
                     /locus_tag="KRL22_000426"
     CDS             61414..62334
                     /locus_tag="KRL22_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HBH1270950.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIIFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYGEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            62424..64796
                     /gene="spoIIE"
                     /locus_tag="KRL22_000427"
     CDS             62424..64796
                     /gene="spoIIE"
                     /locus_tag="KRL22_000427"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HBH1270951.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            65147..67039
                     /gene="pepF"
                     /locus_tag="KRL22_000428"
     CDS             65147..67039
                     /gene="pepF"
                     /locus_tag="KRL22_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH1270952.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            67153..68118
                     /gene="galU"
                     /locus_tag="KRL22_000429"
     CDS             67153..68118
                     /gene="galU"
                     /locus_tag="KRL22_000429"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH1270953.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            68618..70222
                     /gene="rho"
                     /locus_tag="KRL22_000430"
     CDS             68618..70222
                     /gene="rho"
                     /locus_tag="KRL22_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBH1270954.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            70375..70575
                     /gene="rpmE"
                     /locus_tag="KRL22_000431"
     CDS             70375..70575
                     /gene="rpmE"
                     /locus_tag="KRL22_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBH1270955.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            70720..71613
                     /locus_tag="KRL22_000432"
     CDS             70720..71613
                     /locus_tag="KRL22_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HBH1270956.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            71631..72479
                     /gene="prmC"
                     /locus_tag="KRL22_000433"
     CDS             71631..72479
                     /gene="prmC"
                     /locus_tag="KRL22_000433"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBH1270957.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            72523..73587
                     /gene="prfA"
                     /locus_tag="KRL22_000434"
     CDS             72523..73587
                     /gene="prfA"
                     /locus_tag="KRL22_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBH1270958.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            73716..74396
                     /locus_tag="KRL22_000435"
     CDS             73716..74396
                     /locus_tag="KRL22_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBH1270959.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            74425..75465
                     /locus_tag="KRL22_000436"
     CDS             74425..75465
                     /locus_tag="KRL22_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBH1270960.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVASKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            75482..75931
                     /locus_tag="KRL22_000437"
     CDS             75482..75931
                     /locus_tag="KRL22_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HBH1270961.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            75948..76400
                     /gene="rpiB"
                     /locus_tag="KRL22_000438"
     CDS             75948..76400
                     /gene="rpiB"
                     /locus_tag="KRL22_000438"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH1270962.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            76436..77065
                     /gene="upp"
                     /locus_tag="KRL22_000439"
     CDS             76436..77065
                     /gene="upp"
                     /locus_tag="KRL22_000439"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBH1270963.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            77366..78181
                     /locus_tag="KRL22_000440"
     CDS             77366..78181
                     /locus_tag="KRL22_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBH1270964.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            78407..78844
                     /locus_tag="KRL22_000441"
     CDS             78407..78844
                     /locus_tag="KRL22_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBH1270965.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            79029..79256
                     /locus_tag="KRL22_000442"
     CDS             79029..79256
                     /locus_tag="KRL22_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HBH1270966.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            79261..79647
                     /locus_tag="KRL22_000443"
     CDS             79261..79647
                     /locus_tag="KRL22_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HBH1270967.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            79650..80354
                     /gene="atpB"
                     /locus_tag="KRL22_000444"
     CDS             79650..80354
                     /gene="atpB"
                     /locus_tag="KRL22_000444"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBH1270968.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            80423..80683
                     /gene="atpE"
                     /locus_tag="KRL22_000445"
     CDS             80423..80683
                     /gene="atpE"
                     /locus_tag="KRL22_000445"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBH1270969.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            80806..81303
                     /gene="atpF"
                     /locus_tag="KRL22_000446"
     CDS             80806..81303
                     /gene="atpF"
                     /locus_tag="KRL22_000446"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBH1270970.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            81300..81845
                     /locus_tag="KRL22_000447"
     CDS             81300..81845
                     /locus_tag="KRL22_000447"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBH1270971.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            81862..83364
                     /locus_tag="KRL22_000448"
     CDS             81862..83364
                     /locus_tag="KRL22_000448"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBH1270972.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            83392..84270
                     /gene="atpG"
                     /locus_tag="KRL22_000449"
     CDS             83392..84270
                     /gene="atpG"
                     /locus_tag="KRL22_000449"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HBH1270973.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            84283..85677
                     /gene="atpD"
                     /locus_tag="KRL22_000450"
     CDS             84283..85677
                     /gene="atpD"
                     /locus_tag="KRL22_000450"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBH1270974.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            85680..85940
                     /gene="atpC"
                     /locus_tag="KRL22_000451"
     CDS             85680..85940
                     /gene="atpC"
                     /locus_tag="KRL22_000451"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HBH1270975.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            86402..86782
                     /locus_tag="KRL22_000452"
     CDS             86402..86782
                     /locus_tag="KRL22_000452"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBH1270976.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            86797..87258
                     /locus_tag="KRL22_000453"
     CDS             86797..87258
                     /locus_tag="KRL22_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH1270977.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            87279..87869
                     /locus_tag="KRL22_000454"
     CDS             87279..87869
                     /locus_tag="KRL22_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1270978.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            87884..89041
                     /gene="alr"
                     /locus_tag="KRL22_000455"
     CDS             87884..89041
                     /gene="alr"
                     /locus_tag="KRL22_000455"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH1270979.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            89074..89361
                     /locus_tag="KRL22_000456"
     CDS             89074..89361
                     /locus_tag="KRL22_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBH1270980.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            89330..89713
                     /locus_tag="KRL22_000457"
     CDS             89330..89713
                     /locus_tag="KRL22_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBH1270981.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            89884..90711
                     /locus_tag="KRL22_000458"
     CDS             89884..90711
                     /locus_tag="KRL22_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH1270982.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEEMNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGVDNE"
     gene            90704..91645
                     /locus_tag="KRL22_000459"
     CDS             90704..91645
                     /locus_tag="KRL22_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH1270983.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKTF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIVKTVKEAIIAKRM"
BASE COUNT        36987 a         9896 c        16902 g        28014 t
ORIGIN      
        1 atttttttta ttttttgtca aaaaaaacaa aaaatacgta tttctttttt catttcggga
       61 aaactaaaca caggaattat ggactttata aaaatttaat tcttgaggag tgatataagt
      121 gaaaaaagtt gctttaattt tagctataat aggtgcgctt aactggggtg caattggtat
      181 tctaggtaca gacttaatag gtagtatctt tggtggaaca tatgaaatgg taagtagaat
      241 aatatacttc attgtaggtt tagctggatt atacttaata ccaagtttaa tgtctgatga
      301 tagagaataa tttatgcttt tatgttaaat acctcattct aaatgtttag aatgaggtat
      361 ttaattttat aaaaatatta atttgtttct tttttaatgg taaaatagat aagaattgaa
      421 gttttaaaaa gaagtattat gtaaaaaagg agtactatta atatatgttt attattaatg
      481 aattaaataa gattgtaaat gaagaagtaa tatcttttca tatgcctggt cataaaaagg
      541 gacaggttta taaaaagtta ggatataaag atatactaaa aaatttgtat aaaatggata
      601 caactgagat attaggaaca gataatttac actttccaga aggaattata aaaaattcac
      661 aaaaaaaagc atcaagagta tttaaaagtg attatacttg ctatttagta aatggtagta
      721 gctgtggaat acaatctgca ataatgtcag tatgtagtcc taaaagtaaa ataataacaa
      781 atagagactg tcatcagtct gttataaatg gatgtatttt aggagatata gatatagagt
      841 atgtgccttg tgagataagt gaagagacaa atgtcttaaa agggatatct ataagtaatg
      901 tgattgatat aatagataaa aacttggatg caaaagcagt actgcttact tatcctacat
      961 attatggaat gacatatgat ttagaataca tatgtaatta tgcacatagc aaaaagatgg
     1021 tagtgatagt agatgaagca catggtgcgc atttagggct tagcgagagg cttcctaaaa
     1081 cagctcttga gcaaggcgca gatatagttg tacagagtac acataaaact cttccagcat
     1141 ttacacaatc gtcaatgata catatacagg gagaccgagt tgatatagat aaaatattga
     1201 acatgttaag aattacagaa tcttcaagcc cttcatattt attattatct tctctggaat
     1261 tagcagtaga tatatatgaa aataaaggaa aagaattaat ggaagagctt ttaaataata
     1321 ttataacttt caaaaataaa gttgattcaa atattaatat atacgacaca aatgataaaa
     1381 caaaaatatt tatatcatct aaaaacatgg gtttaacagg ttatgaacta gaaaatattt
     1441 tgagaaataa atataacata caagtggagt tatctaatta ttatggagtt cttttaatat
     1501 gtacaatagg aaatactgtt gatgatttct ctagtttaga aacagcatta aacaatattg
     1561 taaaggaaga ctttaaattt gaaaagttag aaaataaaaa ataccctgtt gttattccaa
     1621 agaaaatatt aacacctaga gaagcatttt ataaaactaa aaaaagtgtt aaaatatatg
     1681 acagcatagg taaagtttgt ggtgaatgta tagttccata cccacctgga ataagtgtaa
     1741 tatctcctgg tgaagtaata agtaaagaaa taatagacta tctaatgttt tgtcattcta
     1801 aaggcatgat tgtgagtgga ttgaaagatg tagatttaaa ttttatacaa gtaatagatt
     1861 tagaagacat ttaaaaatta tgatataaaa gtagatagaa gtagatagtt taaaattgtg
     1921 aagagaaata aatagactgc ttatatagag atatctaata aaagtactaa aaaagtaaaa
     1981 agtgtttgta tggaggatat gaaaatgaaa ggtaagttaa taattataga gagtggttca
     2041 gatgcaagtg gaaaggctac tcagacagaa atattatatg aaagattaaa aaaagaaggc
     2101 tatatgatta aaaaggtaga atatccaaat tatgaatctc catcatctgc cttggtgaaa
     2161 atgtacctaa aaggagactt tggtaaaaat gcatcagatg tagacccata tatagcatca
     2221 acttttttta cagctgatag gtatgcatca tttaaaaccg attgggagga gttttacaat
     2281 gaaggtggaa taattatcgc agatagatat acaacctcta atatggtaca tcaggcctct
     2341 aaaatggata tttgtgatag agaagagtat ttaaattggt tagctgatta tgaatttaat
     2401 ttatttaaga taccacaacc tgattgtgtt atatttttag atgtgcctat tgaatttagt
     2461 aaaaagctta tggagaatag aaaaaataaa attacagggg aagaaaaaaa ggatattcat
     2521 gaaagtgaca tagagtattt agagaaatct tacaacaatg ctttatatat agcagataaa
     2581 tatgattgga aaaaaataaa ttgtgtttta gataacaaat taagaagtat tgaaagtata
     2641 cataatgaaa tttataaaat agttcttgat tcaataaaat ctatggagag ataaatatgt
     2701 attttgaaaa tattataggg caagattttg caaagaaata tttaacaaat tctataaaga
     2761 aaaataaact taataatgcg tatatgtttg aaggaatgga tggaatagga aaaaagaaat
     2821 ttgcagatga attatcaaaa ctattacttg attatgaaaa tctcgaaaat agtccagact
     2881 atgtactcat aaaaccagat ggaaatagta taaaaatagc tcaaatcaga aatttacaat
     2941 cagatatagt aataagacct cataaagact ataaaatata tataatcaat aatgctgaaa
     3001 aaatgactgt ggaagctcaa aatgcacttt taaagacgct agaggaacct ccaaactatg
     3061 ctataataat cttagtcaca aacaacaagg aatctttatt agaaactata aaatctagat
     3121 gtgatataat aaagttctca cctataccaa ttgaagactt aaaacgttat ttgataaata
     3181 caggtataga agaagaaaga gctcaattat tggctatttt ttcgagagga agtattgaga
     3241 atgctctaaa tctatctcag tcttctgagt tttcaatgat gagagaagat atacaacagt
     3301 atattcagat aatgttagat aaaaacatag tggagatttt aaatatacca aataatatgg
     3361 aaaaatatag aggtaagatt atagctttat tagatatgat gataaactat tttcgagata
     3421 tcatcctatt aaaagaaaat gtaaacaaga acatgttaat aaatgtagat aagctagttt
     3481 tcattcaaaa tatgagtgga aaaattagtt attctcaatt gtccaagatt attgatataa
     3541 tagaagatgc aaagagtaaa ataaaaagca attgcaattt caatataagc atacaagtta
     3601 tgtctttaaa tatatacgag gtgattaaat gataaagata gtaggtataa ggtttaaaag
     3661 tgctgggaaa atatattatt ttgaccctgt tgattttaat atagagcaag atatggatgt
     3721 agttgtagaa actgcaagag gcttggagta tgggaaagta gtcgttggtc caaaagatat
     3781 ggatgaaagc gaattagttt ctcctttgaa gccaattata agaatagcta cagaagaaga
     3841 taaaaaagta tatctagaaa ataaggaaaa ggcaaaagaa acttttgagt tgtgccaaca
     3901 aaaaataaaa gaacatgagt taacaatgtt tttaatagat tgtgagtata cgtttgatag
     3961 gaataagttg attttttact ttacagcaga aggaagaata gattttagag aattggtaaa
     4021 agacttagct gctatattta aaactagaat agaacttaga caaataggtg tcagagatga
     4081 agctaaatct ataggaggtc tagggccttg tggtagaaaa ctttgttgtt catcttggtt
     4141 aggtgatttt caaccagttt caataaaaat ggcaaaagac caaagtctat ctctaaatcc
     4201 aacaaaaata tctggaatat gtgggagatt attctgttgc ttaaaatatg agcatgatgt
     4261 atatagtgaa gcaatagaaa aaatgcctgt tgtaggtgca ttggtgcaat cagatgatgg
     4321 aaaaggaaaa gttgtagaag tgaatccttt attagaacaa attaaagtgg aatttcaaga
     4381 caagacagta aagatataca caagagaaga tataaaaata cttagagagc ctaaaaaatg
     4441 tgatggctgt ggtggtaaat gtaaggataa tgatggatta gatgaagcca cactaagaga
     4501 gctaaagaaa ttagaagatt aaatttaagg tagggctttt cctacctttt ttaaagcaat
     4561 taatgcttaa agttattaat atttgaggag aatttatata tgcaattaaa agattcagaa
     4621 agaatagatg atttacaatt aaaaggcctt aaaattatac aagatactaa tggtttttgt
     4681 tttggtatag atgcagtttt attagccaat tttactaaaa taaaaaaaga tgccaaagta
     4741 gtagatttgg gtactggaac tggcattata cctattttga tagctggaaa aagtgaagct
     4801 aaaaaaatta ttggagtgga aatacaagaa gatgtatatg aaatggcaac tcgttctata
     4861 aaattaaatg gattagaaga aagagttgag attataaatg aagatataaa atacatagac
     4921 aaagtcttag acataaatgg ttaccatgta gtcacatcaa atcctccata tatgcatatt
     4981 gatggaataa aaaatccaaa tgataaaaaa gcaatatcaa gacatgaagt aaggtgtaat
     5041 ttggaagatg taattagagc tgcatccaga ttggttatgc ctagaggaaa attcttcatg
     5101 atacatagac caacaagatt ggttgatata ataactttag ggagaaaata taaattagaa
     5161 ccaaaggtta ttcaatttgt gcatccaaga cctcaaaaag caccgaactt agttttggtt
     5221 caatttgtaa aagatggaag accagagctt aaaatattgg acccattgta tgtttatgga
     5281 gaagatggga attatacaaa agaattaaaa gcaatatata ataataaaga tataggagag
     5341 ttgtaaatga gcgggaaatt gtacatatgt ccaacaccaa taggaaacct agaagatata
     5401 acatatagaa ctttaagaac attaaaagaa gtagacttga ttgcagcaga agatacaaga
     5461 catagtataa aacttttaaa tcattttgaa atctcaaaac cactaactag ttatcatgaa
     5521 cataataagg attcaaaggg agattatttg ataaataaac taattgatgg tgaaaatata
     5581 gctctgataa gtgatgcagg tatgcctggt atatctgacc caggagaaga gataataaaa
     5641 caagctatac aaaataacat agagatagaa gtattgccag gtgcaacagc ctttgtaacg
     5701 gctttagttg gctctggtat ggacacacat agatttgttt ttgagggctt tttagataga
     5761 gataaaaaag ttaggaaagc acaattggaa gaattaaagg aagaaagtag aactataatt
     5821 ttctatgaat caccacatag attgaaggat acactaaaag atatgcttaa aattcttggt
     5881 aataggaata tttctataaa tagagaactt acaaaaaaat atcaagaaat aataagagaa
     5941 aatatagaaa ctaccataaa aatatttgag gaaaaagaag taagaggaga atttgtatta
     6001 atagtagagg gttttcatgg tgagaagtca aagaaagaaa attatgatgg gcttacagat
     6061 agggaatatg ttttaaaact aattgaaagt ggtatgaaca aaaaagatgc aataaaaata
     6121 gtttgtaaag atagaaagtt aaagaaagat gtggtttata aacaagtttt agatttataa
     6181 aacctgaatc tgaggtgatt ttatggaaat agggaaaatt ataatagaga gtttaaagag
     6241 ggaagataca cataaaatat ttatagaatt agataataag catgaattag aaaaaataat
     6301 tcctaaaata agctgtatga agtctgtagg tgaatgtaaa tatcatgtag taaattgttt
     6361 tgaacattct ataaacgcat taaaagaatt agaaatagta ttaaatgata aggatttttt
     6421 tccaatacat ctaagaaaac atgtgtcaaa ctatttaaac acatatattg aagaaggaat
     6481 aaataagtta catgtattaa agctgggaac atttttacat gatataggta agcctgacag
     6541 tatgacctta gatgaaaccg gaagagttca tttcacaaat catgaaaaaa taggtgctca
     6601 aataattgac aatatgggaa taaatttaga gttatcaaca gagacatata gacttataag
     6661 taaatatgta agatatcata tgatactttt gtctctatat aagaaaaatg atttgagtag
     6721 gaaagaatta attaatgtat ttaacttagt agatgaggac actataggtg taataatgct
     6781 tgggtatgca gatatagtgt ctacagtaaa attattgggt aagagtggag aagtcagtgt
     6841 gttaaagaca tatatggaat atattttaac aaattacttg tataagagta attatacaca
     6901 tgtataaatt tagttaatat aattgagttt tagatgatta attaaagttt gaaatatacg
     6961 gatttcaaaa acataaaaga agttgtcttt gttgtaaaat tatgaaagac aacttttttt
     7021 atatcaaaaa ttgaaatttt attaaggata cttaatggtc tattaattaa taaactatta
     7081 gtatttaatt tatattacaa tattgatttt gcttgtattg gcgttgatag tataacagag
     7141 gtcttagtag aaccaatttt ctttatagta tcaatcacat tttctagctc gtacatatct
     7201 tttacaatta cttttaaaag taagcaatca tcacctgtta tatggtgaca ttctacaatc
     7261 ctagggtcct ttgcagctga ctcaataaat tctgtatatc cattgcttgg aagagaaata
     7321 tgaataaatg cctttataac tctgcctaat gaatctgggt tgacaatagc tttatatcct
     7381 tctataacac cagactcttc taatcttttg actctttctg aaactgcagg agaagttaaa
     7441 ccaactattt ttcctaagtc cttcatagaa attctcccat catcctgtaa aatttctatg
     7501 attctgtaat ctgtaacatc cataaataaa cagtccccct taaataaaaa taattaatgc
     7561 tataaaactt tcttagaatc tatcatttgt gtttttaaat accaaagatt tctagataaa
     7621 tcaaccttat aaatgtgtgg ttttgaaagt cttttgtatt gttcccagat agtacttaat
     7681 tcatattgta catgattttt tatttcaaga acagcttttt tattatattt gcatctgcct
     7741 tttatataca atggtttaag aagctcttta actttgtaat ttgtaaatac cttcgttttc
     7801 catgtataag taggatggaa gatttctaaa ggtttagact catctataac ttcatcatgt
     7861 aacataatca aatctgcctc tgccttattg tcttcgttat atattcttat aactttcttg
     7921 taaccaggat tatttatttt ttctggattc tcagaaatct ttatcttagg ttcaagaact
     7981 cctttttcac aagatgcagc taatttataa actcctccaa gagaaggtga atcgaaagat
     8041 gtaatgagct ttgtacctac tccccatgaa tttatagtag ctccttctgc tttaagtgat
     8101 gttatggtat attcgtctag gtcattagat gcagtgatgc tgatatctga aaagccagcg
     8161 ttatctaatt gttttttagc ttctttagat aaataagcta aatctccaga gtcaagtctt
     8221 atacccatag gtttgtatcc tttttcagaa atatttttga atacttttat tgcattagga
     8281 actccactgt ttaatacatc ataagtatct acaagtagta ggcatttatc tggataaaca
     8341 tcagcatatg cttggaatgc ttcaagttca ttatcaaatt tttgtaccca actgtgagct
     8401 tgtgtaccaa ttataggtat atcaaacatt ttccctgcta gtacgtttgc agttccagca
     8461 caaccaccaa ctacagcagc cctagcccca tatatccctg catctggacc ttgtgcacga
     8521 cgtaatccaa attcaaatac agggtctcct tgagctgcaa agcaaactct agaggcttta
     8581 gtagcaataa gagactgaaa attaactatt gttaacaatg ctgtttcaat aagttgagct
     8641 tgatataaag gtgccttaac agtaattaat ggctcattag ggaacatgat agttccttcc
     8701 tcaacagcat atatatctcc tgtgaattta aattctttta aaaattttaa gaacttgtca
     8761 gaaaataaat ttaagttttt taagtactct aaatcttcat ctgaaaaatg aagattatct
     8821 atgtattcaa caacctgatc aataccacaa actatagtat accctccatc acaagcgttt
     8881 tttctaaaaa acatatcaaa tacaacaatg tcttcatgaa tattcttttc aaaatagcca
     8941 tttaacatag taagctgata taaatcagta agaagtgtta gatttctcat tatttctctc
     9001 cttaattatt attaaatatt aaaaattgta aaaactccca cacttatact aaaacataat
     9061 atagtacaac tttcaagtat aaagtattac ctaactatca taaaattatt taaagaggag
     9121 gatgattata ataggaaaaa tatggtttta tatggtatcg ataggaataa taggaagctt
     9181 gatttctaaa aatatgggtg aattaaataa agttatatta agtgaaacat caaaaggtat
     9241 agagtttgca ataagtctag ctggtatcat ggcactctgg atggggataa tgaatatcgc
     9301 aaaagaatca ggtttaattg aaaagatagg tcaaaaacta aatcctataa tgagaagatt
     9361 atttccttct attccaaaag gtcataaagc aatgtcttat atagttatga atattgcttt
     9421 aaatatgttg ggtgctggaa atggtgcaac agcatttggt ttaaaagcaa tgagtgagct
     9481 tcaaactttg aataacaaga aagatacagc cactaatgat atgattatgt ttatggtaat
     9541 caatatatca tctatacaaa taattccatt tactataatc aaactaagga tggatatggg
     9601 ggctcaaaat ccaagtgaaa taatttttac gactttattt gcaaccataa tatctacagc
     9661 agtagcaata ataacatgta aattttttca aagaagatat agataaaggg gatgtagata
     9721 catggagata ttttcaaact tacttatacc aataataatt ctgtacatag tagtttatgg
     9781 taaatataaa aaaatagatg tgtatgatag ttttgtaaaa ggagcaattg atgggttaaa
     9841 agcagcatgg gatatcctac catatataat aggtatattt ttggcaatag gaatattcaa
     9901 aactggtaaa ggtcttgata tgttagaatg gctatttaca ccaatagcaa atatgatgag
     9961 tataccaaaa gaattaatag gtctaataag tgtaaaacct ttatctggaa gtggtgcttt
    10021 agggatgtac agtgaacttg caaatagagt tggaatagga agtttagtag aaaaaatggg
    10081 tgctacgatt gtaggttctt ctgagactat tttttacaca atggcaatat actatggaag
    10141 tctgaagata aaaaatacta gacatacatt atcatgtgct atgattagcc atgttgcagg
    10201 tgtcatagca gctgttttta tttgctatgt aatatttgta taatttgttg acaatatggg
    10261 aaaaatttta taatatagtg attatataga aacaaatagt aatacaaatt acaagctatg
    10321 aaaagaagag taaataaagg ttttttctat cagagagcta ggttaggtga aagctagtgt
    10381 caaaagcttt attgaagatg gtcttggagc tttttatctg agcaagtgtg ctagggtaaa
    10441 acggttggac acgttatagt ctactaaggt atctataaaa tgtttctaca tttcatgtga
    10501 aacataacta ttatagatga attagggtgg taccgtgaat aatctcgccc ctatgttaac
    10561 tcataggagg cgatttttta ttatttaaat gaaagaatca tatgattacg aacgataaaa
    10621 aattaggagg taaataacat gagcaaaccg agtttttatg taacaacacc aatatactat
    10681 ccaagtggag gattacacat aggacatact tattcaacag tagctgcaga tacaatagct
    10741 agattcaagc gtttctgtgg atatgatgta aagttcttaa caggaacaga tgagcatggt
    10801 gaaaaaattc aaaagaaagc catagaacaa ggaatgtcag agatagagta tcttgatgga
    10861 atgataaaag atataaaggc cttatggaat actatggata tatcttatga tgattttata
    10921 agaactacag aaaaaagaca tacagacata atacaaaaga tatttactaa actatatgag
    10981 caaggtgata tatataaagg tgaatatgaa ggtagatact gtactccttg tgagagtttc
    11041 tggacagaat ctcaattact agaaggaaat aaatgccctg actgtggaag agaaacatat
    11101 ttagtaaaag aagaatctta tttctttaga ttatctaaat atgaagacag attaaaagag
    11161 ttatttaaag atgatagttt ctgttttcct gctgctagaa aaaatgaaat ggtggcaaac
    11221 tttttagaca aaggattaga agatttaagc gtaactagaa cgacttttga ctggggtata
    11281 aaagttcctt ttgatgaaaa acatgtaatt tatgtgtggg tagatgcttt atgtaactat
    11341 ataacagcat taggttatat gactgataat gatgaagaat ttaaaaaata ttggcctgcc
    11401 aatgttcaaa tagtaggtaa agaaatagtg agattccata caataatatg gccagcgctt
    11461 ttaatggctt taggtctaga agttccaaaa caagtatttg gacatggatg gatactattt
    11521 gctgatgata aaatgagtaa atcaaaaggt aatgtggttt atccagaacc tataatagaa
    11581 agatatggaa tagacacact taagtacttc ttattaagag agtttgcatt tgggcaagat
    11641 ggaagttata ctcatagaaa ttttgtaacg agaataaatt atgatttagc aaatgattta
    11701 ggaaacttaa taagtagaac tgtagctatg gttgaaaaat acaataatgg tataatacca
    11761 acagcaaaag tttcaactaa ttttgatgct gacttaaaag aacaagctgt ttcaactaga
    11821 gaaaactttg aagctgaaat ggataaaatg caattccatg aagcattaga gagtgtatgg
    11881 aaattagtta gaagaactaa caaatatata gatgaaacta tgccttgggc actagctaaa
    11941 gatgaaacta agaaagatga attagacaca gttttatata atttatgtga atctataaga
    12001 ataatcgcaa cactaataaa tcctataatg aatgagactg ctaataaaat atatgaacat
    12061 ataggaataa aaggtcaaga tgatataact acatgggaaa gtacaaaaac atttggtctt
    12121 attggagaaa atgtaaaagt atttaaaggt gaacctttat tcccaagatt agatgtagaa
    12181 aaagagatag aagaattaac taaaatgttc tctgggaaac ctccagtaga agaaaaacct
    12241 ttagagcata aagaagaaat tactattgat gatttagaca aaatagagct tagagtaggg
    12301 aaaataataa gctgtgaaaa acatccaaaa gcaaataaat tattagtatc acaagttaag
    12361 attggaccag aaacaagaca aatagtatca ggaatagctg aatactataa gccagaggat
    12421 ttagtaggaa aagaggttac agtggtatgt aacttaaaac cagttaaatt aagaggtgta
    12481 gaatctcaag gtatgatatt agcagcaggt gatgatggag acccatatgt tttaccattt
    12541 acacaagggg ctaaagatgg atgcgaggtt cgttagtagg taattaaata gtaaggagat
    12601 taaagatgtt atttgactca catgcacatt taaatgatga aagttttgat gaagatagag
    12661 atgaacttat tggttcatta aaagataaag gtgtagattt ggttgtaaat ccaggagcag
    12721 atatagagac gtcgataaca gcaattgaac ttgcgaaaaa atacgacttt atatattcag
    12781 cagttggggt acatccacat gatgtatcaa aactagatga tacagcaata gaaactctaa
    12841 gaaaacttgc aactgagaat gaaaaagttg tagctattgg agagattgga ttagattatt
    12901 attatgatta ttctccaaga gaagaacaaa aagagtggtt taagaagcaa attgaattag
    12961 ctaatgagct aaaacttcca ataataatac atgatagaga tgcacatgga gatacttttg
    13021 agataataaa gaatactaaa aatcctgaaa taggatgtgt acttcattgt tatagtggaa
    13081 atgtagagtt agctagagaa tatgttaaga tgggttgtta tatatcaatt ccaggcacgg
    13141 ttacttttaa gaataataaa aaaactagag aagtagtaag agaaatacct ctagaaagat
    13201 tattcataga gactgattca ccatatatgt caccagagcc acatagagga aagagaaaca
    13261 atccttccca agtatctttt gttgctgata agatagccca ggaaaaaggg atatcttatg
    13321 aagaagtatg tagagttaca aaagaaaatg caaagaaatt ttttaatata aaatagacaa
    13381 attaaatctt ataatgatat atataataag tcattataag tataggatga gagtgcctca
    13441 aaatgagttt tttagtttat gaggcactct ttttgtatga aatcaaatat attttcatca
    13501 tttcaacaat gaaaaagaag tttatcatat tttgagatag tttgttttta tttatttaat
    13561 tcatatttta aaatatattt tcttaacatt gttaaaaaag aatttacaag atattcatta
    13621 gaattaactc aactctaata ttcacttaac ttaagttgtt tattatatta ttaaagagaa
    13681 gtaaacgaaa ggtagattaa ggaggttgaa ttttgtatac agttgatagt actaagatat
    13741 tgataaatat gaacttagag aaactagaaa agatatactc aatgataaaa gatacatcaa
    13801 gtatttctat aattaaagaa cctaacttgg ctacagtaat ggtaagagct aatgaaagtg
    13861 taaaaaacac aacatttaat ttaggagaga tattagttac tgaatgtagt gtaaaggtag
    13921 atgaaagctt gggttacgga atagtttcag aaaacaataa taagaaagcc atttacttag
    13981 cagttataga tgcagtttta catagcaata acagtaaatt tgatgagtta aagaattaca
    14041 taaataaaag tgtatatgaa gagaacttaa ggtatgaaca agagattatt gatgaattta
    14101 gcttgattaa taaaacgaaa gttcaattca atgctatgga ttaaatagga ggagaatcat
    14161 ggtaaattat acacaagaaa tatatagaaa gatgctagat agtgcttcat ttcctgggaa
    14221 attaaataat atagataata taaatataga aaataataca aaactattga atggagcaat
    14281 tggtatagca atcactttat tagaccaaga agttaccttc tatatagaaa attatactca
    14341 aaaagatata aaaaatataa gagcacttac aatgtcaaat caaatagatt atagaaaatc
    14401 agattatata tttttagata ttaattcaga agtggatata ttacagatta aaataggttc
    14461 ttttgaatat cctgatgaaa gtgcaactat agtacatcaa gtaaatgatt tatcaacgta
    14521 ctctcaaact aagtatataa agcttgattt gagtggtcct ggtataaaat ctaaaaatag
    14581 tatatatata aatggaatta gagaagaatt tatagaaaga ttatctacca taaataaaga
    14641 ttatccaata ggaatagatt tgattttagt agataaaaaa ggagaaattg catttatacc
    14701 aaggtcatca aaattaagtt gggaggtatt gtagaaatgg cttatgtagc agttaaaggt
    14761 ggagaagaag ccatattaca ggctaaaaat atacttgagt tttatagggt aaaaggagat
    14821 agcttgccta tagatgtaaa gcagattgag gaacaaatgt cttatgctgt agacaaagta
    14881 atgtctgaag gaagtttata caacaaggaa ctatcagcat tggctataaa acaagctcaa
    14941 ggtgatatat tagaagcctc tttctatgta agagctttaa ggtcaacaat gcctagaatt
    15001 acatattcag aacccataaa tacagaagaa atgagaataa aaagaagaat atcagctact
    15061 tttaaagata taccaggagg tcagtatctt ggggcaacta gagattatga aaatagaata
    15121 ttgaatgtag aattattaga agaagatgaa aaaaagaata gagattttag agatagtttt
    15181 ataaatgaat tagaaacagt agatgaaatc cctgaattta caaaaatatc taatatattt
    15241 agaaaagaaa atttattaca agaagaagtt tgtgaaaaca aattggaaga agttattgat
    15301 gatattacaa gaaatagttt aagatttcca gtttctaggt cagcaaagtt acaggcatta
    15361 actagaggtg aaagtggagt agtgtcaggt tttgcttatg ctattgtaag aggttttggt
    15421 gatgaacatc catatataag tgaacttaga actggtaatg tatttataaa agtaaaacat
    15481 cccatctatg aagatgaaga aataataata ggggatatgc tggttactga atgtgaaata
    15541 gtttcaaaag catcacaaaa taagactgaa aattctaaaa ctaattcgga agataaaaat
    15601 aagatgtctt taggatatgg tctttgtatg gggaataatg agaataaggc tatatctatg
    15661 gccatactag acaaatcttt ggagccaaat agtgaaaaac tagcacaaga tgaagaattt
    15721 gtattgcttc atatagatgg aatagattca ttaggattta tatctcactt taagcttcct
    15781 cactatgtag attttaaagc ggatgtagaa agaataaaat agtttgtgga ggtaagttta
    15841 ggtgatatat aactatggtt ttttagacga aaacacaaaa aaagaaataa gaagaaagat
    15901 attaaaagca atatcaatac ctggttatca agttcccttt ggttcaagag agttgcctat
    15961 agctaaggga tggggtactg gaggtttaca attaacacta tcattaattg gtaaaaatga
    16021 tgtagtaaaa gtaattgacc aaggaaatga tgattctaca aatgcttgta atataaggag
    16081 ctttattgca agtgtaagta atgtagaaac cacaaaagat acattagaag ctacattgat
    16141 tcaaacgaga catagaatac cagaagaaaa acttaaatct aatcaaatac taatatttca
    16201 agtaccaata ccagaaaccc ttagaatagt agaacctagt gaagtagaaa caagaagaat
    16261 gcattcagaa gaagattata gtaggatgtg ggtatatctt tatgaagata tagttagatt
    16321 taatgatata tctatagcag ttgaatatcc atgtaaagta aatgatagat atttaatgaa
    16381 tccatcacct atacctagat ttgatataaa aaaattaaat atgtcagaca atttattctt
    16441 gtttggtgca ggtagagaaa aaagaattta tgctattcct ccatatacaa aggtagaacc
    16501 tttagagttt gaggattata agtttgaaga ggaaaagttt gaaggaaaat actgtagttt
    16561 atgtaacagt acaaatacat ttttagatga agtatatgac agtgacacta gtgaaaagta
    16621 ctatagttgc tcagatacaa gttattgtga aaaagttaga ttaaaaaata acagtataga
    16681 tgtgacaata ggaggtactt ggaatgagta aaataaatga ctctaaaaga ttagaaaata
    16741 tagacaagca agtattaata ggaagaaata tcaatcttat ttatggagat gggtgtgaaa
    16801 agtgttttga aagcacagga tatgaaagca ataatatatg taagtattgt ggttctatag
    16861 ttgcatgtaa taatgtaaat ttagaacttt atgaaggaga agtccttgga attgtaggtg
    16921 aatctggttc aggaaaaagc actttattaa aaatactgtt tttccaagaa catgcaaata
    16981 gtggagaagt atatatatcc cattacaata aagacacaaa tatactagag ctttcagacc
    17041 aaaaaaagag atacataaag aatcatttta tgggtattgt gtatcaaaat ccccaccttg
    17101 gtttaaattt agactttagt agtggtggta atatagcaga aaaattattg atggcaaatt
    17161 tatataatgt tgaaaaaata agagatagag gcaaagaact tttaataaaa actaatatac
    17221 ctgtagaaag aatagaccat aaaccaaaat actttagtgg gggaatgcaa caacgagttc
    17281 aaatagcaaa agctctttca aataaccctc caatattgct attagatgag gttacaacag
    17341 gtttagatgt ttctgtgcaa gcggaagtat tggatttaat aagagaaatc caaagagaac
    17401 ttaagatttc tatgatagtt gtatcccatg actttgatgt tataaagatg cttgctgata
    17461 ggacaattgt aatgaaaaat ggaagtgtaa ttgagtctgg tcttacagac caaataatgg
    17521 aggacccaca acacccatat actcagcaac ttataaattc attgctataa atatcgtttg
    17581 taaataagca aaatgggggt ttttaataaa atgaaagaaa ctatacttga agtaaataat
    17641 tttagtaaag actttgagtt acatgcattg aacaagacta taacggcatg tagtaatata
    17701 agttttgaag tttcaaaagg tgagttttta ggaataatag gtaaatctgg agcaggtaag
    17761 tctaccatat taaaaagtat ctataaaaca tatataccaa caactggaga aataattttt
    17821 aattcagaaa tatatggtaa tgtagacctg gctaaaattg gagaccgaga aatgataaat
    17881 cttagaaaga aagaaatagg atatgtatca cagtttttaa agacacttcc acgaataact
    17941 gcaattgaac tggtagtaca ttctttaatt gagagtgggt ttgaaaaaga ttgttcgtat
    18001 gatatggcca aagatatact taaccaattt gaaataaagg aaaatttatg ggatgcgtat
    18061 ccaaataatt tttctggtgg agaaaaatta agattaaatt tagctcaagc tatggtcaaa
    18121 aagcctagac ttttgttact tgatgaacca actgcatcac ttgataatca atctaaaata
    18181 tatgtaaaag aaaaaatgtt ggagcttaaa agtcaaggaa ctacaatgat aggaattttt
    18241 catgatatag agtttatgga aactgttata gataagacct ttactatggc aaaagggact
    18301 ataagtgaaa gtggggtagc ctagatgata aaactaattc ataatgcaaa tattgtatta
    18361 gaagatatga ttttagaaaa tggtcattta atcatagagg gagatacaat aaaaaaagta
    18421 tcaaatgata agattgatta cgcatttgac tttaatgaga tagatgaaat aatagatgca
    18481 aaaaacttat atgtaatacc tggtattata gatattcaca gtgatgccat tgaaaaggaa
    18541 atagagccaa gaccaagtac attattacca tttaatatgg cattttatga actagataaa
    18601 aaactacctg caaatggaat aactacagtt tatcattcta tatctttagg ggatggagta
    18661 ggagttagaa gtattgataa ctctttaaag atgattaaaa atattgattc atataaaaat
    18721 atagatagta agagcataaa tcataaagtt catttaagat atgaagtgtt gtattatgaa
    18781 ggtttagaaa aggttttaga actattagat gaaaataaaa tagactactt atcaataatg
    18841 gaccattctc caggacaagg tcagtataca aatccaacat tttataaaga gtatgctact
    18901 aaagtgtggg gagttacaga aaattatgta gatacatggt tagatgattt agtaaatctg
    18961 catgataatt tagattggaa taaaatagct aatattatag gtatagccaa aactaaaaat
    19021 ataaatgttg catcacatga tgatgataca ttagaaaaaa tggatttcat aaaaaatata
    19081 ggcataaatg tatctgaatt tcctataact cttgaagttg caaaacattc aaagaaattg
    19141 ggtgttctaa cttgtttagg tgcaccgaat attgtaagag gtaaatctca taataacaat
    19201 ttaaaagcaa tggatgctat attggaagat tgttgtgaca ttgtgtgttc ggattatctt
    19261 ccatcagcta tgataaagtc tatgtgtata gttgcagaaa gaataaataa tttaaataaa
    19321 gcagtcagtt tatttacctc aaatcctgct aaagcagttg gtatatatga tgaaagaggt
    19381 agtataaaag aaaataaaaa agcagattta gttttagtag atattgatag tgaatatcca
    19441 aaggttgtaa atactattgt aaatggaaaa acagtttata aaagggaggt ataaagattg
    19501 ctaacagagt tacattgtca tacaagtata tcagataata attttactac tgaagaaata
    19561 ataaaaaaag cagcagaaaa gaatataaat atcttagcaa taacaaatca tgacacatta
    19621 tctggattgg atgaagctct tgtgcttgga gagcattatg gaataacaat aataccaggt
    19681 atagaaattt cagcctatga ttataaaaat agaaaaagag ttcatattct tggatataac
    19741 atagatttaa acagtcaaga aataaaaaat ttgtgcaatc caatggtatg tgacagacat
    19801 aaagcatctg ttaagatggt aaataaaatt atagatttag gatacaaaat atctttggaa
    19861 gatgtaaaga aatattcatc aaagactgga atatttaaac aacatataat gaaagctctt
    19921 atagataaag gatatacaga taatatatat tcaagtctat ataaagaatt gtttcataga
    19981 ggaaacggca aggtatatgt atctttaaaa tatgtggatt acagagatgc aataaaagct
    20041 ataaaaaatt ctggtggaat ttgtgtgtta gctcacccgg gtcaaatgga taattttagc
    20101 gctattgaag agatggtaaa agtaggatta gatggaatag aagtatatca tccatctcac
    20161 aacaaagaac tagaaaaaga gtcgctttct tatgctaaga agtataatct agtggtcaca
    20221 ggaggctcag attaccacgg attttattct caacataatt atgaacttgg aagcaagagc
    20281 ttaaataaag aagatttatt taagtttagg ttagctttag gaggggtatt ataaatgtct
    20341 tttttacaag taaaaaatgt aggtaaaagt tatggacaag ttaaggtgtt aaaagacata
    20401 tctattgata ttgaaaaagg agagtttatt tgtttactag gtccaagtgg ttgtggaaaa
    20461 agtacactgc ttagaataat tgcagggctt gaggataaac atggtggaaa aataataata
    20521 aatgataagg atatgactaa ttcaccacct gaaagtagaa attttggtat agtttttcaa
    20581 tcatatgcat tatttccaaa tatgaatgtt tacaaaaaca tagcctttgg actagaaaat
    20641 aaaaacataa gtaaatctaa tattgataaa aaagttaaag aagttctaga agttgtagaa
    20701 ttaagtggat atgagaaaaa atatccatca caattatcag gtggacaaca acaaagggtt
    20761 gcattagctc gtgcgattgc tttagagcca gactttttac ttcttgatga acctttatct
    20821 gcattagatg caaaagtaag acttaaactt agggagcaga ttagaagttt acatagaaaa
    20881 ctaggcatta caactataat ggtaacgcat gaccaagaag aagctctttg tttagctgat
    20941 aagatggttg ttatgaatag aggagaaata atacaagttg gaacaccaaa ggaggtatat
    21001 aaaaatccag aaacaccttt tgtagctgat tttataggaa caataaattt tatagatgat
    21061 ggtattaata agatagctat tagaccagaa gatataaaag tagagtctaa tagagattct
    21121 aaagataagg atataaaagt gggagaaatt ttagatatcg aatttagagg atttaactat
    21181 agaattacag ttgagtatcg ttctaagcaa atgaaattag atgtagtttc caaagttgca
    21241 gaacaaatga aactatgtat aggttctaaa ataaacttta agatacctaa agaaggaatt
    21301 gtacaatata aatcagaggg atgtgcttaa tagctagggg tgaataaatg ataacatcaa
    21361 aaaataaaag aagaataagt gatagcacaa tacaaaaata tttcttgatt ttttcggtaa
    21421 ttgtactaat agtatttata ttatttccat tagtatcatt attaaaaaat gcatttatgg
    21481 atacaagtgg aaattttata ggaatttcaa actttagtaa atatgttgaa aatccaagtc
    21541 ttatagcatc atttaaaaat tcaatttttg tatctacagt ctcatcttta atatcactat
    21601 gtttagcatt tatatattca tacgcaataa caagaacaaa cataaagttt aaagattttt
    21661 ttaaaactat gggaatgttt ccactttttg caccaactat gttatatggt atttcactta
    21721 tatacctttt tggaaataag ggaatcttta caaccatggg tctggaagta ccactatatg
    21781 gtccattagg aataattatt tctcagattc tatttacatt tccacaagct tttttaatat
    21841 tatctgtagc actttcgatg gctgattaca gactttatga agcagcagat agcttgggtg
    21901 ctagtgaatt taagaaattt tgcaaaataa caattcctgg tataaagtac tcattactta
    21961 gttcattctt tgtatccttt atacttgcat ttacagattt tggagcagct aaggtagtcg
    22021 gaggaaacta caatgtactg gctactgaca tatataaaca agtagttgga caatttaaca
    22081 taccaatggg agctactgtt tctatggtaa tgttaattcc tgtactaata gcatttacat
    22141 tagataagat ggcaagtaag aaacaaggta tgaccataac tgcaaagtct atgccatata
    22201 agattaagga aaataagttt agagatagag tatttttaat agtatgtagt tttataacat
    22261 tgctaatttt tattttaata ttcgtttcag ttataggttc agttataaag ttatggccat
    22321 ataatttaag ctttacaatg aaacactata catttaaagg tattttggga agtggaataa
    22381 aaacatactt aagcagtttg aaaatatcaa ctttaacagc aatatttgga actatatttg
    22441 tattttttag tgcttatatg atagaaaagg tggataagtt tcctaaatta agacaaacag
    22501 cttacctttt atcaatgata ccaatggcct tacctggctt agttttaggt atatcatata
    22561 taactttttt taactcagca agtaatccat taaatttttt atatggaagt acagcaatat
    22621 tagttatagt aaatgtagtt catttttatt cagtttgttt tataacctca aattcatctt
    22681 taaaaatgtt ggataaagag tatgaattag ttgcaaaatc cataaatatt ccattttata
    22741 aagtattttt taatataaca gttccaatgt ctataacatc aatacttgaa atagtagtat
    22801 attattttgt aaattcaatg gttactgttt cagcattaat atttttatat acacctcaaa
    22861 ctcagactgc atcaatatca atactaaagt tagatgagat aggatatata ggaccatcag
    22921 ctgctatggc agtattagtg cttttaacaa atataatagt aagacttttg tacgaatttg
    22981 taacaaagaa attaaaaaat aacacacaaa aatggcagca aaaagatgtt gcatagggga
    23041 ggtaaaaatg aaatttaaga agctagtttc tttaggagta ttatcaacac ttttattaag
    23101 tgtaataaca ggatgtagta ctgattcatc aggttcagat tcaaagtctg atagtaagac
    23161 aaaaggggat ttaacagttt acacagcaat tgaagaagat agtatagagc catatttagc
    23221 tacatttaaa gagaaatatc cagatattaa attaaatatt gttagggcat caacaggaga
    23281 tataacagca agattattag cagaaaagga taatcctcaa gcagatgttg tatggggagt
    23341 tgcagccaca agcttattgg ttgcagatga ccaggggatg ttagaactat atgctccaaa
    23401 aggttctgaa gaaatagagt ctgcatttaa agatgataaa gaagttcctt cttgggttgg
    23461 gatagatgct tggatgacag gtataacagt aaacactaaa gaattaagtg ataagaacat
    23521 cccagttcct agttcttacg aagatttaat aaagccagaa tataaaggtc ttatatctat
    23581 gcctaatcca tcttcttctg gtacagggta cttaacagta tcagccctta tacaaattat
    23641 gggtgaagaa aaagcatggc agtatatgga taagttacat gagaatattg gtgtatacac
    23701 tcaatctggt tcagctccag ctacatcagc agcttcagga gaatatccta ttggtatatc
    23761 ttttggatat agaggtataa agttaaaaga ggaaggctat ccagtagaag tagtatttcc
    23821 aaaagaaggt tctggatggg atatagaagc aaatgctctt gtgaaaaaag ataatataaa
    23881 agaagcatca aaagtatttt tagattgggc tataagtaaa gatgcaatga acgaatactc
    23941 taaaaactat gcagttacta ctatttctac aggaaatcca ataccagaag gattccctaa
    24001 aaagccatta gagcaaatga tagataatga tttaaaatca gcagcaaaaa atagagaaga
    24061 tatactaaat aaatggatat caaaatatga tggtaagaca gaaaaagaga gttaagtaaa
    24121 actatacaaa tggagtaaaa agaaaaattt ttttaagtag attttattat aataatataa
    24181 gttgagaata atataggtca agaaaagtga atattctata aaaatgtata gagtaagtat
    24241 accattcagt ttgaatggta tattttttat ttttagagat taatttagaa atagatatac
    24301 tacagtttaa aatagtatat tttaatttca ttattaaagt atagatgtta tatataaagt
    24361 aaataagata ttaaataatt ataaactaaa gtaaataaaa tattgagcga ttattaaaaa
    24421 gatatatata tatataattt aatttgagca gtttgttata tattataaaa aagagaaaaa
    24481 taaaaggtaa attgtttctg gataacttaa aattggaagt aagaatattt aactagagaa
    24541 gaattattta agctcaggtt agctctagga gtagctgatt ttataggagc aatagatttt
    24601 atggatgatg atataaacat gatagcaatt agaccagaag atataagggt agaatttaat
    24661 agagatttca aagaaattat agacctcaaa ctcagaccgt atcgatataa aaactaaagc
    24721 tagatgatat agtgttgtat ataggaccat cagctgttat ggcagtatta gtgcttttaa
    24781 caaatataat agtaaaactt ttgtatgaat tgataataaa aaaattaaaa accaagacat
    24841 aaaaatggca acaaaaagaa attgaataag ggaggtaaaa atgaaattta agaagttagt
    24901 ctctttggga atattatcaa cacttttatt gagtgtaata actggatgta gtaatgtttc
    24961 atcaggttca aacttaaagt ctaataataa gacaaaagga gagttaacag tttatacagc
    25021 aattgaggaa gatagtatag atacatactt agctacattt aaagagaaat atccagatat
    25081 taaattgaat gtacttagat tatcagtagg aggtataaca gcaagattat tagcagaaaa
    25141 agataatcct aaagcagatg tgttatgggg tgttgcagct acaagtttga taattttaga
    25201 tgacaaagaa atgctagagc catacgctcc gaaaggcttt gataaggtaa atcctgcatt
    25261 taaagatgat aagaaagttc cttcttgggt tggaatagat gcttggatga ctggtataac
    25321 agtaaatact aaagaattaa aagctaaaaa tatatcagct cctagttctt atgaagattt
    25381 aataaagcca gaatataaag atcttatatc tatgcctagt ccagcttctt caggaacagg
    25441 atatttaaca gtatcagaac tcatacaaat tatgggtgaa gaaaaagcat ggcagtatat
    25501 ggataaattg cataaaaata ttggtgtata cactcagtct ggttcagcgc cagctatatt
    25561 agcagcttca ggagaatatc ccattggtat atcttttgga aatagaggta taaagttaaa
    25621 aggtgaaggt tatccagtag aagtagtatt tccaaaagaa ggttctggat gggagataga
    25681 atcaaatgca cttgtgaaaa aagataatat aaaagaagca tcaaaagtat ttttagattg
    25741 ggctataagt aaagatgcaa tgaatgagta ttctaagaat tttgcagtta ctacaattga
    25801 cacgggaaat ccggtaccag aaggatttcc aaagaatcca ttagaacaga tgatagataa
    25861 tgatttaaaa tcagcagcaa gaaatagaga ggctatacta aataaatgga tagaaaaata
    25921 tgatggaaag acagaaaaag agagctaagc cttacaataa aatttagtac aaaaagcgcc
    25981 tagaatataa gttttatatc taggctcttt tgatatattt atttaaaatg catatttcta
    26041 tataaaaata aatagtttag taccttgatt aaattaaata aaaaccttaa aataaagaga
    26101 tgtaaagaaa aactaaaaac gaataaaagg tgaatttata tgataaaaga aataatagta
    26161 gtagagggta gagatgacgt tacagcagtt aagagagcaa tagatgcaga acttataact
    26221 acaggtggat ttggatttcc aaaaggtgta atggagcgta taaaagctgc taatgaaaga
    26281 cgtggtgtta taatatttac agacccagat tttgcaggtg aaaaaataag aaaaaaaata
    26341 gcatcagaag ttccaggatg taaacatgca tttctaccaa gagaggaagc taaaaaggat
    26401 ggagatatag gtattgagaa tgctactcct caaagtataa tagcagctct gaataaagtt
    26461 agaactgaaa atacagaaaa aagagatgaa tttaagcaag ttgacttaat tagaaatggt
    26521 cttataggta atgaagaagc atcacttaga agagatgcac ttggaaaaat acttggaatt
    26581 ggatatggaa atgcaaaaca atttttaaat agattgaata attatggagt tgaaagagaa
    26641 gaatttatag atgcattaaa acaaatctaa acgtaatgtt taatgtatga aaaatatgta
    26701 tataaaataa attgtggaat tacggttaat ttaagataaa ttatttataa tatacacctt
    26761 attttaaatc aatgtaaata catataaata agtataatta ataaaattaa atatcaaaat
    26821 aagttaaaaa ggagtaaata atggatagac tatcttcaca taatgcaaca aaggaagtag
    26881 tacaaaaata taattttaaa ttttcaaagt ctttaggtca aaatttcttg atagatagta
    26941 atataattga taaaatctta tctggagcta gaatcacaag aggagataat atcatagaag
    27001 taggacctgg tataggaact cttactcgtg agatgggtaa aatagcagaa aaggtagtag
    27061 ctatagaaat cgatagaaat ctaattccta tattgaaaga taccttgtca gatttagata
    27121 atacagaggt tgtaaatcaa gatatactaa aagtagacat acaggaatta gtaaaagata
    27181 aattaaatgg tgggccagtt aaacttgtag caaatcttcc atattatata actactccaa
    27241 tagttatgaa atttttagag gaagacatac ctgtaacaga catagtagtc atggttcaaa
    27301 aagaagttgc agatagaatg aatgctattc cgggtactaa agattatggg gcattatcta
    27361 tagctgttca atactattgt gatacagaga ttgtggcaaa agctccaaga catatgttta
    27421 taccacaacc aaatgtagat tccacagtta taggtttaca tgtaagagat aaaagaaaat
    27481 atgatgttca taatgaagac atatttttta aaacagtaaa agcatccttt ggacaaagaa
    27541 gaaaaactct tcttaattcg ttgggaggtc ttggttttct taataaagat gaaataagag
    27601 aagtattaaa agaagctaat atagacgaaa aaagaagggg tgaaactctt agtatagaag
    27661 agttttctgt tctttcaaat ataataaata caaaagtatc ttctaaatag aaggtacttt
    27721 tttttatttt gttaacatat attgtttaga gaaactgtgt taagggggga ttgcagtggg
    27781 ttctaaaaga aagtttaaaa gagactatat aatactagaa gctaaagaca taaactttag
    27841 atacaaagaa cgagtactgc caaaagcttt tgcaaaagtt gaagtaaatg atgaaaaagc
    27901 aattattgca ttatatgtag aaaatctaaa atatgttaaa gatgggtata aagcagtagc
    27961 aataaaagat gaccatggat taatagactt aggaaatata attttaaatg aacaaggaag
    28021 aggtgaattt gttttagatt tagaagattc tgatgatgag ataaaaggta ttgcattatt
    28081 gtatgaaaga aatatacctt taattggatt taagggaaat aagcttgaaa attatgagga
    28141 tatattattc caagaggtag aggaagaaga atatgaagaa tatgaagagt tggaagaaga
    28201 agacgaagag atagaggaga atgaggaaag tgatagagac gaagttagtg aagaagaata
    28261 tattatagaa gaatatgatg aagatgagta tgaagactat tgggaagatg atgaagatat
    28321 tgaagaagga gagttaaaag caagaacgga agtagaagat tctggtgatg aggaaataga
    28381 agagttcaat aattataagg aaatagaaaa ttataatagg gttaaagtac aggaagaata
    28441 tatagacata gaatatgatg aggaagaaga ggaagaagag gaagaagaag aagtttttga
    28501 agtaaataga gaagaagata ggtttgtttc ctcaaaacct actaaatcaa agaaagttca
    28561 aaaagatcag aataatattg aaaaaataaa aagagctaat ggagtaagtc aaggagagag
    28621 tggaaataaa caaaccagta cattacttat gccaagacaa ataaaaaaag gtttgaaatt
    28681 atttaaagaa gtaaaacctt ttgtaacaga ttatatagat aagacaagat ggtggaaaat
    28741 agagataaat cctacaacat tgtgtggata tacaatgcct tatttaggat atttaaacgt
    28801 gttgaattac accatgtata gtgatgcagt tttacattca tataaataca gacactattt
    28861 atttggtgtt cagtatgatg aatataataa gagaaaacat tatatttatg ctatcccagg
    28921 aaatagaaat gaacagccag acaatggaag cacaggattt ttaagatatc aagcttgtga
    28981 taatagaaca aatagtttag gatattggct atgttttata gattctagac aaagaaatat
    29041 agttaggtaa aaacaataaa aatgaaaaaa tttagactca attcttattt tactgaaaaa
    29101 attaatgaaa tgtagtacaa aactttaaaa actattgata atatttaaat attacactac
    29161 aatatatctt gaaataccta ttatattatg gaggaaaatt atgataaacg agcaaagaat
    29221 tttaaatgag tttcttgaat tagtacagat agatagttta tctttaaaag aggggaatgt
    29281 tgctaaagta ttagttaaaa aattagaaga aataggttgt tcagtagtaa tagacaatgc
    29341 tggtgaaaaa gcaaatggag aaactggtaa tataatagct acattaaaag gaaataaaga
    29401 aggaaagaaa atattattta gttcacatat ggatacagta actccaggta taggggtaaa
    29461 acctatagtg gatgaagcaa atggaataat aaaaagtgat ggtactacaa tattaggttc
    29521 tgatgataaa gcaggtatag cagctatatt agaaggctta agatatataa atgaaaataa
    29581 tatagaacat actgatatac aagttgtatt ctctatatgt gaggaatgtg gattagttgg
    29641 agctaaaaat ttagactatg gaaaaataga ttctgaatat gcatttatat tagatagtgg
    29701 tggttctcca ggtgaaataa tagtaaaagc tcctgcacaa gatgtaataa atgttaagat
    29761 attaggaaag actgctcatg caggtcttga acctgaagct ggaataagtg ctataatggt
    29821 agctgccaga gcaatagaaa atatgaattt acttagaata gacgaagaaa caactgctaa
    29881 cataggaatt ataaacggtg gaacagctac aaatatagta acaggagaag ttaatataat
    29941 tgcagaagcc agaagtctaa aagaaaataa attagatgtt caaactaaac acatggtaga
    30001 gacttttgaa aaagctgcaa aagattttgg agctcaaatt gagatagatg tcaatagagc
    30061 atatacacca atagatgtta gtgaggattc tgaaataata aaacttgcaa agaaggcttt
    30121 ttcaaactta ggtatagaag gtcatactga atctacagga ggaggtagtg atacaaatat
    30181 attaagtaag aatggtatcg aagctataac tttaggaatt ggtatgaaaa atgctcatac
    30241 actaagtgaa catatagcta taaaagacct atatgattct gctaaaatgg tagtggagat
    30301 aataaaggaa gcataaattt aaataatagt gtataatata tatatcgcct agcttaagct
    30361 aggtgatttt tcattttata gaagattgat aatctctatt gaaagcaaag agtatacatt
    30421 tgcatataag agagtgttta atttatgttc aaatgtaggt tcttaataat atttagattg
    30481 tttcataagg gaggaataaa tatggaaaca aggtatgaag aagcaaataa aataacaata
    30541 caatcaatac tttggaatat agtattaaca ataattaagg ttatagctgg tgttattggt
    30601 aattctagcg ctatgattgc ggatggatta cattcagcat cagatattat aagttctata
    30661 ggagtactaa taggcaatta tgtatcttct agacctggag atagagagca taattatggt
    30721 catgagaaag cagagacatt agtatcattt gtgttatcaa tattgcttat tttcgtttct
    30781 ataacaatag gtatagaggc aattaaatct ttatttaact tagatgcatt aagtgttcca
    30841 tcaatattac cattagtagt atcagttatt tcaatcctga taaaagagta tcaatataga
    30901 ataacaataa aagttgctaa aaagataaat tcaccagccc taaaagctga tgcttggcat
    30961 cataggtcag atgctttatc ttcagtagct gcttttatag gtataggtgg ttctatttta
    31021 gggtttaaac cattagaccc aattgcgtca gttgtagtgg ctatatttgt agctaaagta
    31081 ggaattagta tacttataag ttctgttaat gaattgatgg atgtttcagt tgatgaagaa
    31141 gagataaaag aattaaaatt tattgtagca gatacagaag gtgttaaaaa tcttggtgat
    31201 ataaagacta gaaaacatgg agctatggca tatgtagatt tgactatatg tgtggatgaa
    31261 aatttgacag ttaagcaagg tcatgatatt gctaccaagc ttgaaaaaca tataataaaa
    31321 catatggaat ttgtaaaagg aataacagtt cacgttgaac catgcactaa ttgccaagga
    31381 aataagtgta ataattaatt aaaacttaaa aaaaagtgta aaaagttata taattgtttt
    31441 atgattataa actctagggg tggttaaatg agcaagaaaa gaaaactaaa gaaaaaagct
    31501 gcaatattaa taggagtagt tgttttcttt ataatatact ttatatcctt tagaatagga
    31561 ataaatatgg aaaaggataa aagtgaagtg ccaaagaagg tagaaaaaga agaagaagat
    31621 aataggtctt taaggactca aataaaagag aagaagaagg tttatatatc agataaaaat
    31681 atagaaaaca taaaaattga agaagatatg tgggatgaaa taaagttatt tttctcagat
    31741 tttaagaaag taagaaatac tacttcttct tacgaagcag tttatgaagg ttattctgat
    31801 gatggagtta aattttctac tgaccttaac ttttttagag tatatactgt aaataaagaa
    31861 gaatattata aagtaccagt tagttctaag gatgctttta agaaactttt agatgagagt
    31921 atatatactt cgtttgacct tttaagtcat tataaagatt ggaaagaggt tactataact
    31981 catggaaaag aaattaaaaa agttcataga tggaaatttg atgatttagc acataagatg
    32041 atttcaaaga gggttgtagg aaaagttcaa cctgagaaaa gtaaggaaag aagtgactat
    32101 aattttacta taaatataaa aggtgataat tttgatgtaa aagttgatac aatgggaaaa
    32161 gattatgtaa aagttacttc taagaaaaat gtatcttact atgaggttca tacaagttta
    32221 tttgattacc ttaaaaatga gatatttgaa attggaaaga aataagactt taagaaggct
    32281 atcaaattag atatttgata gcctaaatta ttttatatat tatttttcaa ccaacaagtc
    32341 tgcaacctta taaattggac cagcaccagc agttattact aaatcattat ccttaacatt
    32401 ttcacgtaag tattttacta tatcttcaaa ttcttttata tagatggcat ctacattgtt
    32461 ttgatataat ttctcaacca agtccttaga atgtatatct cctgggtctt tttccctagc
    32521 agcatatata tctgttatga taactttatc agcagcatag aatgcctctg aaaattcacc
    32581 taaaagagat tttgttctag tataagtatg tggctggaag atacaccata aagttgattt
    32641 ttttaatttt ttggcagcag ctaaagttgc ttttaactca gttggatgat gtgcataatc
    32701 atctactact aaagcattct tataataccc tttagtttca aatcttcttc cgacaccttt
    32761 ataaattttt atattttttc ttatagtctc taagtcaata ccagaaacaa gagctgccat
    32821 tatggcagaa gaagcattgt atatgttatg aagaccatat acagaaagtt caaattctcc
    32881 taaatctctt ccttcatatt ctattctaaa tattccatga ccactattgt caaagtgaat
    32941 atcttttatt acagcatcat tgtcagaatc tctgccgtat tttataatag tagctttaac
    33001 atcatacaat atgtcatcaa tattttcatc atcgccattt attatgaaat agccttctgg
    33061 gggtaataat tttccaaatt tgttaaaaga agccttgatt tcatctattc cagagaaata
    33121 atcaagatgg tcttcttcaa catttaaaac tatagatatc tttgggttaa aattaaggaa
    33181 actatctaca tattcacatg cttcagttat aaagtggttg gaattaccta tcttaacatt
    33241 accacctatc atacttaagt taccaccaac tagtatagtt gggtctaagt ctgcatattc
    33301 aaagattgta gataacatag atgttgtaga agtttttcca tgtgttccag aaactgctat
    33361 agaattttta tattccctca tgatttggcc taaaaaagtt gctctgttca ttaccaattt
    33421 atttttttct ttagcagcca caagttcttc attgtctgga tgaactgctg ctgtataaac
    33481 aaccatattt acatcatctg atatattatc ttttttctga ccaatataaa tagttgcccc
    33541 ttggtcccta agtttgtcta ataggtatga ttcgtttgaa tccgaacctg aaacttgata
    33601 acctttattg atacatattt cagctaatgc actcatgctg ataccgccaa ttcctataaa
    33661 gtgtatattc ataataaaac cacctttctt tttaattaag tcctacaata tgaactattt
    33721 ctgtggtata ataatataat gttcaatatt ttataattaa tatgcatata atattatatg
    33781 tattttattt ttgaatataa taaaacataa gtaatattat accacaataa gaattgttat
    33841 gcattagtta gtttaacgtt atataaaggt acttgtagga ggaaataata atgaaattta
    33901 aaagaacaga gagaattgga gcaatagtta aaatactgtc tgataatcca aataaaatat
    33961 atactttaag ttattttaca aatcaattta atgcagcaaa atcaacaata agtgaagatt
    34021 tattagttgt aaaaaatgta tttgagaagc tacatttagg taaagttata actatttcag
    34081 gagcagcagg aggagtaaaa tatataccta aaacttctat agcagaaaat gcagagttct
    34141 taatggaatt atgcgagaga atatgtgaca agtctagaat actatctggt ggttttttat
    34201 acttgattga cctaatttac gaccctacaa tagctgctaa gataggaaag atattcgcat
    34261 caaatattga gtatgtagat gcagattatg ttgtgacaat ggaaacaaaa ggtataccta
    34321 tggcacttat gactgcaaaa gctatgaatt tacctctagt tataataaga aaagatataa
    34381 aggtatcaga aggtcctaca cttagcatga catatgtgag tggaaacagt tctaaagttg
    34441 aaagtatgag tttgccaaga aaagctctta aaccagatag taaagttata attatagatg
    34501 atttcatgag gggtggaggt actataaaag gaatggtaga ccttatgaat gaatttggtg
    34561 cagaggttat aggtactgga gtattcatat ctacaacgaa tccttcagaa aaaatggtaa
    34621 aagattatat ttcattgatt caattggatg ttaatggaga taaaatagta gtagaaccaa
    34681 acttaaagac ttttaaagat gaatatagaa atgaagattt agacgaagaa gaagattcag
    34741 aatttgaatt tgagatagat gaagattaat aaaaaaaata tttagaaaaa tatgtaaaaa
    34801 taaaaagagg atatccctag ttgttcatag aattatttaa aaaacagttt atattaattt
    34861 attccagcga taataatttt aatataaatt aatttctgtc aaaatcaaag ggggatattt
    34921 tggtatgaag ataactgacg taagagtaag aaaattaaca gaagaaggta agatgaaatg
    34981 tatagtttca ataactttcg ataatttgtt tgtagtgcat gatataaaag ttatagaagg
    35041 ccataatggg ctatttatag caatgcctag cagaaaagta ggcgaaggaa atttcagaga
    35101 tatagctcat ccaataaatg cagaaatgag acaagtttta gaagatgcag ttttacaagc
    35161 gtatcatgaa gcattagttc aatgggaagt agctgctgaa taataataaa tatataaaat
    35221 ggagagagcc cgaacattta ggctcttttt aaatgtagaa tttctattaa aatatgtact
    35281 ttttagtaaa aaagtgctat attattagtg ataatgtata tgttgtatac aaattgttag
    35341 ataaatgtat tataatgtat attgattaag agaataatac gaataaaatt aaattagatt
    35401 gaatggagtg tatcaatgaa ctttaaagct ataatccttg ctgctggcaa aggaacaaga
    35461 atgaagtcta aatacccaaa agttatacat aaagtatgtg gaaaagaaat ggttaaccat
    35521 attatagatg tttcaaaaaa atcaggggta aaagatactg tcgtgatttt aggacatgaa
    35581 gctgatgtag ttaaagaaaa gcttgcagaa gaaattataa tagccatgca aacagaacaa
    35641 cttgggacag gacatgctgt aaagatggct aaagaatata ttaatgatga agatacaata
    35701 gttgtacttt gtggagatac tccacttata aaagaagaga cactaaagag actatttgaa
    35761 tatcatatag aaaataaata tcatgctaca gttcttacaa caagagttgg aaatccaaca
    35821 ggttatggta gaataataag agataagaag ggtgaccttc ttaaaatagt ggaacaaaaa
    35881 gatgcaaatt cagaagaaaa gatgataagt gagataaact ctggaattta ttgttttaat
    35941 ggaaagagtc ttagagaagc actagatttg ctaaataata acaattcaca aggtgaatat
    36001 tatttgactg atactgctaa aataatgaga gataaaggat taaaagttgg tgcatttgca
    36061 ggttcaacta ttgaagaact tatgggcgtt aactcaagag tagaattatc aaaggcagaa
    36121 gaaattatga gacgaagaat aaatgaatct catatggtaa atggagtaac tataatagac
    36181 actaactcta cctatataga atctgatgtt atgataggta atgatactat aatatatcca
    36241 ggtgttatgt tacaaggaaa aacaaggata ggttcagatt gtataattgg aatgaattca
    36301 tctataacaa attcagaaat aggtgatggt acagaaataa aaaattcaac tataattgat
    36361 agtaaggttg gagaaaattc tactgttggg ccatatgcat acttaagacc aaagagtgac
    36421 ttaggaaata atgtaaaaat aggcgatttt gtagaagtaa aaaatgctat tatagaagat
    36481 ggctcaaaag catctcacct ttcttatata ggagatgcac atgtcggtaa aaatgtaaat
    36541 attggatgtg gagtagtatt tgtaaactat gatggtaaaa ataaatttaa atcaatagta
    36601 aaagacaatg cgtttatagg ttcaaattct aatttagttg caccagtagt tgtagaagaa
    36661 aaaggatata tagcaacagg ttcaacaata acacatgatg tcccagatgg tgctttggca
    36721 atagcaagag aaagacaagt tatcaaagaa ggatgggtag aaaaaaagaa tcaaaaagac
    36781 gaccaaagta agtaattatg tagtttatta ttttggctaa aaaatttagc tcgaaattat
    36841 tataaattat attcattagt attttaaaat tttcaggagg gttacataaa tgaatactag
    36901 cggaagcgag attaaaatta ttgcaggtaa ttcatcgaaa gagttagcac aaaaaatagc
    36961 tgactatata ggtgtatcag tactagattg tgaagtaggt acatttagtg atggtgaaat
    37021 atgtgtaaac atgaatgaga cagtaagagg ttgtgatgtg tttgtagtgc aatctactaa
    37081 cagcccagta aatgataact taatggagtt attaatctta attgatgcgt taaagagagc
    37141 atcagcaggt agaataacag cagttattcc ttactatgga tatgcaagac aagacagaaa
    37201 ggctaaggca agagatccaa tcactgctaa attagttgca aatttaataa ctgctgctgg
    37261 agcagataga gtattaacaa tggatttaca tgcagctcaa atacaaggat attttgatat
    37321 accattagac cacttactag gtggaacaat attagcaaat tattttaatg aaaagaaaat
    37381 agaagattta gtagtagtat ctcctgactt aggaagtgtt actagatcaa gaaaatttgc
    37441 taatacttta aatggagaag ttccaatagc tataatagat aaaagaagac cgaaagctaa
    37501 tgtatgtgaa gttatgaact taataggtga tgttaaaggt aaaaatgtta tactattaga
    37561 cgatatgata gatacagcag gaacaatagt taatgctgca aatgcactta aagagtttgg
    37621 agcaaaagat gtttatgctt gttgtactca tggtgtgtta tcaggtccag ctattgaaag
    37681 aattgctaat tcagaaataa gtgagttaat agttcttgat actatacaac ttcctgaaga
    37741 gaaaagaata gataagataa agataaaaac agtagctcct ttatttggag atgctataag
    37801 aatgatattc tctaatgaat cagtaagtaa attattctaa tttattgtat ttatgagagt
    37861 tgtttaaaag gatataaacc ttttgagcaa ctcttttttg attttatact tatggaatgt
    37921 tatttttttc ttgttagaaa ggtatatatt attgtaaaaa gagattatag tttaaaatta
    37981 tgtatattta agtaaaataa acctaataaa gggtatatta ttcaaaatat tatgaatata
    38041 aaaaatatta caaaaaagta ttgaaaaaat tcagattatg tagtattatg taaatataaa
    38101 taaagaaaga ggtgtttcca atgggaaggt tagaagatga acccctaata attaaatgat
    38161 tcagtcacaa tctaaagtga atataaaaat ctattgaaag tttatttata agaattgaaa
    38221 atagtatcta ttctatcttt agtgtttgtg agagggttct ggattatata agattactgt
    38281 aaagagtaat tttgcacaat aagcatatct gtaaatgaag agtttcgttt atataatgat
    38341 tgtggctgaa tcataactat aatagataga atgtttataa tagatgattt tataaaatac
    38401 tatattgtaa tagcttttag ctttcaaata aatattagta aaggatggaa atgacaatga
    38461 taaaactaaa tgataattta taaatatctc cttacgatat ataataattg tagggagatg
    38521 tttctttttt tgtatagcat aatttttcta gaaattctgt ttcaatatgt aaaaagttgg
    38581 tatatataaa tagtataaac agtgttgcta aaatatggta gatattatat aatataagtg
    38641 gatatgtata tacattatga gttatataat ttgaatttaa taaaatagaa acgttgattt
    38701 atgttctgta atgtgggcac cttggagcat attgagttag tggtgcaacc ggctatgaaa
    38761 ttgtatttat ttataaatac tattattttc atagcttttt ttatttaaaa aatggttata
    38821 tgttagaaat aaatttggtt agtacgttta aataatttta cttagatttt taaccagata
    38881 tattataagt aagtattaat taaaaaattt aagggggaat gaaaatgaag ttaaaaaaga
    38941 ataaaaaagg tttcacttta gtggaattat tggtagtaat tgcaattata ggtatattag
    39001 cagtagtggc agttccagct ttatttagta atataaataa ggctaaggta gcaagtgttg
    39061 agtctgatta tagttcaatt aagagtgcag cattatctta ttattcagat actaataaga
    39121 tgccagctac aacatcaaat cctgtagatt tagaaaattt aaaaacttat atggaaagtc
    39181 ttcctgataa agcagatata ggtggagagt atcaattact tttggttggg aataagttag
    39241 ttttacaaat aaatgatgct acattaacag gagcgcaatc aacgaagtta ttgagtgatt
    39301 taggtaatga taagatatac aaaactatag gtagcgatga taagcttaca gatttattaa
    39361 ctaccaatga aaaattagat aataaggttc tatatttagt tcttatagat aatgctgaga
    39421 tggattcaac aaaataatta aaactatatt tttataaaga atattgtaaa tttaatgaaa
    39481 aatataatat aaaagacagg aagaaaatct tcctgttttt ttatactatt ttctttaatg
    39541 ttcaattatg aatgatgata taattgagat agtaaaggag tgaaacctgt ggctaaaaaa
    39601 gttagaatag gagacaaact ggtcgaaaaa ggatatataa cagaagaaca gcttaaatgg
    39661 gcactatcag aacaaaaaaa cagtggaaaa agactaggag aatttctagt acaagaaggg
    39721 cttatagata gtaacttact aataagtgta ttaaaagaac tcttggatat agaaagtata
    39781 tttttagaag ggacagaaat agacacttta gctacaaaga tggttccaga aaatatatgc
    39841 aaaagatata ctgtatttcc attcaaaata gatggaaata aaatatgtct agccatgtca
    39901 gacccacaag acagagaagc agttcaagat gtaaggcgta tgtcaggtaa agatgtagag
    39961 atatttatat caagtacaga agatataaac aaagcaatag gtcatgctta tgcacattca
    40021 gaaataaata aggcaatgac tgagtacaac aaaaatagaa ctggtggagt aagagaaaca
    40081 gtaatacttg aagaagatgt aaatgctgct ccaatagtac gattagtaaa taacatacta
    40141 gaaaatgctg ttagaatgga agcaagtgat atacatatag aacaaagtga aaattacatg
    40201 cgtgttaggt ttaggataga tggaatgtta agagaatata tgaggatgaa ctcagcacca
    40261 tataaggcag taatcagccg tatcaagata atgtcagata taaatatatc tgaaaagaga
    40321 ataccacagg atggtagaat ctatttaaaa gtagataata aacccataga ttttagggtt
    40381 tctacaatgc caactaacag ggatgaaaag atagctatga gggttcttga taagagtaat
    40441 tttatggtta gtaaagaagt actaggaata gacgaacatg gctctaagat atatgatgaa
    40501 ttgataaaca ctccttatgg tcttatattg gttgttggcc ctactggaag tggtaaaacc
    40561 actacattgt attcaatgtt aaatcaacta aatacagaaa atagaaatct attaacaata
    40621 gaagacccta tagagtatga attacctggt gtaaatcaat ctcaaataaa tgaaaaggca
    40681 gggcttactt tcgccagcgg acttagagct tttatgcgtc aagacccaga tataataatg
    40741 gttggagaga taagagatac tgagacagca gaaatagcaa ttagagcttc tcttacagga
    40801 catttagttt taagtacatt acatgcaaat acagcagttg gagcaatttc acgtctttta
    40861 gatatggatg tagaaagttt tttaataact tcatctgttt taggtgtaat atctcaaaga
    40921 cttacacgaa aaatatgtga gcattgtaag gtttcatatg aagcagatat tggagaaaaa
    40981 aaggctcttg gtattgatgt aaatgaatca gtaactattt atagaggaaa aggttgtgaa
    41041 aggtgtaata atactggata taaaggacgt ctaggtatat ttgaaatgct tgaaattact
    41101 ccagaaataa aagagttaat agattcatct gcaaatcaaa gagaaatttt aaagatggct
    41161 agaaaacaag gtatggttag cttaaaagag gatatagtta aaaaggtttt aaatggaaag
    41221 acaacagtag aagaaatgat tagaataatt ttgatgactg attaaaggat gatattatga
    41281 aaagttttaa atacacagta ataaaagagg acggaaaaaa gcaaactgat gtgattgaag
    41341 ccaacgattt taatgaagct agaaatcttc ttagaaagag aaatcttaga gttattgaaa
    41401 tcaaagaaag caaaaataaa aatataagat tatctagtag aaagagaaaa aaagacttag
    41461 gagctgacca gataagccac ttttgtagac agtttgctat tatagtatct tctggtataa
    41521 atagtatttc tggattagaa acattagcta gaaggtcaac taacattaca ttaagagaag
    41581 aaattaatcg tatagtggca gaaataaaag taggttctac tattgcagat tcaatgcttt
    41641 catcaaaatc aaagtttcca aagttacttg gtgctatggt agctacaggt gaagctacag
    41701 gtaaattaga tgaagtatta aaaagtatgg cttcatttta tgcaagtgaa cacagggtta
    41761 aacaaaagct tagaaatgct gcaacatatc cattaatagt tttgatttct tcatttataa
    41821 tgatttttat atttacaaca tttatggtgc ctaagatgat taattcaatt acaacagtag
    41881 gagcaactct tccacttata acaagaattg ttatggggtt tggtatgttt atgaagaagt
    41941 tttggataat agtactttta gttattatat tatttatcta tcagtttaaa aaatatctaa
    42001 aaacgtcagt tggaagggct cataaagata gagttataaa caagatacct gttttaggaa
    42061 aaggaataaa ttgtatggta gctacacgat tttcaagagc attgtatcta tttgtatcaa
    42121 caggataccc attagttcaa gggcttgatt atattataga tagtgtaaat aacaccatgg
    42181 cagagaagat tttagcatca gctaaagatg gaataacaag aggagaaggc ttagcagaaa
    42241 atttagagag atatacgtat tttgactctg tgttggtaca gatgatagct ataggggagc
    42301 agacagggga attagagaat ataagtagac agatggcaga attttatgag tatgaatccg
    42361 aaatttattt aaataggatg gcctcaatga tagagcctgt tttaataatt gcagttggta
    42421 ttatagttgc gatactggtt gtatcaatat ttatgccaat gcttagtata tatgatgcca
    42481 tgtaggaggg aaaggacaaa tgaacaaggt ttatgtatca tattatggcg attctatttc
    42541 catagttgag ggcagatata aacacgataa ggataagttt tatgtaaaaa attttaatgt
    42601 gttttcaata gaggatattg cacaagattt ttctaaggaa aagtatgctc tattgagata
    42661 cgcattagaa aatgttaagt taaaatcaag acatgtagtt ttttgtttaa atacaagaga
    42721 tgtaatttta aaaccccaaa aacttcctaa tatggacaaa aaggatttag atggatttat
    42781 gaagctagag atggacgaaa tgatggcttt ggagtcagat gaatatgtat tttcgtatga
    42841 agtatctagt gaaacacctg ataattcaga tggcgatgaa tcaagcttaa atcttatcat
    42901 tggagctata caaaaggaag aggtaaatgc aattgtagag ataatgcatg aatttgattt
    42961 agtattagat agaatagata cattatcaac agcttactta agaatgctta aaaatttaga
    43021 ctacaatgat ataatggtaa ccaatataag tgacaatagc acaattataa atatatataa
    43081 gaaagatact ttatttatta gtgataatat acctataaag ataactgcta aagatatgga
    43141 catgcaatta ttaaatgtag tagaagaatc aaaaggtctt atgaattact attcgtcaag
    43201 aaactttggc aaggttacgg atactatatt aatattagga aaaagatatt ccaataaatt
    43261 aatttatgaa acttttagct ctgcattttc aagctatgtt tctcaaggcc ttactgagat
    43321 aatggatata tctgatatga taactggaga tatagatgaa gatgatataa attcaattgt
    43381 agagctttta ggaagtatga tagaacctaa agggaaaaga gattttgaaa atataaactt
    43441 tttaccaatg gatatactta gaaaacagat aaaagctaaa caaatgaaaa acatactgaa
    43501 aattgctcca atagttattt tgattcttgc tataccttat ttatgtttaa ttttttcaaa
    43561 taatttagca aataaggaac ttgaaaatgt taatggtgaa ataagaaata ttgaatctgc
    43621 atattatcag attggaaata tagaaaaaat gatacagagt aaaagcgaag aaataaaggt
    43681 atatgatatg ttaattggga aaaaggtaaa gtgggaaaat ttattggatg atatagataa
    43741 aaatactcca agtaaagttg aactaacaag tttatcaaca acttatcaaa atcttggaac
    43801 taataataaa gctgataatt caaaaagtaa taagactaca acagataaat caagtaacaa
    43861 tgaaacaaaa tcaagtacga aaagtgatag taatggagat aaaacagata atgatttaaa
    43921 tgaagataag actacaaatg tgtcagaagc attaactgga aatagtgaga ctaatagtaa
    43981 taacacagat aaagatgata aaactccatt gtatgataag ataccaaatg ttataaatat
    44041 agaaggaaat gctaaagatt cctcttatgt aggtcaattt ttatataaat taaagggatt
    44101 atactatttc aaggatgtta aattacatag cataaaaagt aatgcagaag attctaacta
    44161 tacatttagt atgacattat acctgaaaga aggtgtatta actaatgaat aaagatatat
    44221 ttaaaaaaga tataaaagat atatttaaaa tggaagttag tctaaaaggg attcttataa
    44281 aggttataat tttattagct attttatcat atggttattt tggactttac cctcaatatc
    44341 agaaatatat tgctacaaaa aattctgtaa aacaggctac tgaaaaatta aatatatata
    44401 aagagaaaac tgcacttatg ccaaaatatg aaaaacaact tgaagaagtt gaaagtgaat
    44461 taaaagaaaa aagcaaaaat cttttatatg atatgcaaga tggtcttttt ttaataggtt
    44521 tagataaaaa aatgaaggct tataatattg acttaaccag ttatgacgtt ggaaatgtta
    44581 aagaatacga acatttttat ggtatatcaa caacaataag tgttagaggt gattatagaa
    44641 atgtcaaaaa attaatggct tatttagaag aacaaaaaaa tgttactcaa atactagatt
    44701 atacaatgac ttcatatata gaaccagaaa aagaagagga agaaacaaca aacaataagg
    44761 atttaattaa aaatgtgaac ataaataaag atacaaaaat atactgggtg gaaggcgaaa
    44821 ataagtggca tttatataag gattgtccat tgataaaaga gggagagatt ctaaaaaatg
    44881 acaaactttt agataggtct actaattatc tatgtaatac ttgtgtactt agagctgcaa
    44941 cagaaaaaga agcaaaaaaa gaagtcgtag ctccaaaggc agaaggtgta gtagatgcta
    45001 catttaaatt tataatgtac actaaagaga atactacaat gatacttgat acagataatc
    45061 catcttcatg gagaccagga aaatataatc catttaagtc tagtgcgaaa taaagctaag
    45121 taagctttaa agataggtga tgagtttgta caaaaataat gaaaaaggtc ttactttatt
    45181 agaagtaata atagctgttt ttatactgac aatagtttta agtatttctt ataaagtgtt
    45241 caatggtata acatcagcag taaaaaagca acagattatt acagatgctc aagtaaatat
    45301 taatctaatt aataagtatc taaatagaga tttggaaaac tgtaaagaac taactaaaac
    45361 tggttcaggt aataattatg aatacaatat agagatgcca gataatgttg taaaatatga
    45421 agtttctata gaaactaaaa aaaatacaga ggtatattct gtaacgagaa tccaaaacaa
    45481 tacaattgat acagaaaatg aagttagaga agagataatc tataatcaac cactagttca
    45541 aaacaataaa gaaatgaagg aaacaccatt taaaatagaa aagcaaactg gtaaatctat
    45601 ttatactgta agtatatact ataatgaatc agtgcaagaa agtcataaaa atagcaattt
    45661 aaataacaaa acttatacat ttgatgttat gtcaagaata ggataataag aatttattaa
    45721 aaaataagta ggttgataaa atatgagtaa aaagaatagt gaaagaggat tttccttaat
    45781 tgaagtgtta gtagctatgg ctattatggg aattgtacta tttgcatttt ttaatattat
    45841 caatactaat aacaaagcaa acactaaaaa tgacacagat ataacttcct taaactatgt
    45901 ccaaagtgaa atagaaaatc taagagaaaa gataaaaagt ggagaatttg attttgatag
    45961 tttagataaa ctagaagatg gaactgtcgt atatgaaaaa ttaatagata aatcaaaaaa
    46021 agttgtatat gataaagttc ttagtgaagg tgatgtgagc ttatatgata ctccatatga
    46081 aaagattaca acaataaaag atgaagatgg taatttaatc gacaaaggaa atattacaaa
    46141 taagataaag actattgtag aagataaaag tggtcagata tataaaatag ctgtaactgg
    46201 gaaaagcatg aatgactatt caagtaaaaa agaggttaaa attgtaactg aaatatttaa
    46261 agataaataa ttttacttgg gggtgagatt ttgaggaagt ggaataaatt taaaagtgaa
    46321 agaggggcag ctttagtttt agttttggtt gtagtagcat tgctttctat tgttggattg
    46381 atattttcaa atcagatagc taatagaata aaatctacaa agactactaa tgaaggtata
    46441 caagcaaagt atttagcaga gacatgtgtg gaaaatagta ttaataaagc atatgaaaaa
    46501 ttgtatgatg agcttgagaa aatggataat gaatttaaaa gtgaaaatca agaaaaatcc
    46561 atatctaggt caaaattaag aaatatatca gatgaagatt ttaataatca agatgaggaa
    46621 aatattgaag cagaaagact tggatatatg aataatataa atttctattt aaataaagct
    46681 tcttcagact tggaaaaagc tagtatggaa ttgaaaaagc tatatgattt agatatgttg
    46741 gactatagag acattgaata tgtagatgca aatattattt cacatagaga ttctatctta
    46801 gaaatttgca agaattatac ttctggagat attagtaaaa taaatgaata tattctggaa
    46861 gaagatatag actcaactac attgattgag gcaaagttag tgaataatga tattctttta
    46921 aaaatgtttt tagaagaaaa taaaattgaa aatgaacatt taaattcagc cttttcacat
    46981 acttataagg cattagataa catttctttg gcgatgcaaa atatgattga gtatagacat
    47041 acgtttcata tagatgagcc aaaagtagaa gtatctaatg ggattccaga ttctcaacaa
    47101 tattatgaac taatacaaaa tcctataata aatagtatgg agtatatctg gaatagtaaa
    47161 tgggatacat tagaaaacct attggaaatt ttaccagatc aaactcaagg atttaattct
    47221 ttaagagttc atttgagaaa taatgtaaga aaatttgaga agttaagcga taatatatct
    47281 agtggtaaaa aaaatacagc aaaaaatttc ttaaagtata aagagttatt gtatgaaata
    47341 tcagaccaat gtaatcaact aaaaagtatg tcttatgaga aaatacctgt taaatatgat
    47401 aacatggctt tgataacaac ttttgactat atacaaaatg agcttttagc agagataaaa
    47461 tgcagattaa aagaattaaa accacaagaa attgataaaa cagaaggtat tactataaaa
    47521 ataccttttt ataaggctga ctacgacatg acaaaagaag gatggcctaa attaaaagaa
    47581 aatggttcag gggcggagtt aagcttaatg gtaactggtg ataaagatgg aataaaagaa
    47641 gtagaagtta cagatggtaa aaaaaatatt attggtttag gtgttgaaga aaattcaaat
    47701 tcaaagtata aggttgacgc cattataaac tttaatctaa atatagatac aaatgtagtt
    47761 ggaaattatg atataaaaga taaaattttg attaatcatg atataagttc atacaaaaaa
    47821 gtaaactaaa tataagaagc aacttagtat aaataaataa taaaataatt ttattattta
    47881 ctactaaaaa aataagtaaa ctaatagaag atatggagag taaatattat gtatatttat
    47941 gatttattag agcaaggtat aagactaaac gcatcagata tacacataac cgttggaaca
    48001 aatcctgtag ctagagtaaa aggtggattt gtaaaactaa gtgaacaaat attgacatca
    48061 gaagtaacaa tgcaaatggc aaaagacata gcgggggaat ctatgtttaa agtaatagaa
    48121 gaacatggag aagctgattt ttcagcttct ctaaaaacag gagaaagatt tagggtaaat
    48181 gcatataggc aaaaaggaaa ttacgcaata gcaataagga ctataacagc agaaattcca
    48241 acatttgaaa aattaggcct tccagagagt ataaaatctt ttactgaaaa gcataaagga
    48301 ttagttttag ttacaggtcc aacaggaagt ggtaaaagta caacacttgc aagtatgata
    48361 aatataataa atgaaaaaca acaaaaacat ataattacac ttgaagaccc gatagaatat
    48421 gtacatcatc ataaacaaag tttagtaaat caaagagaag taggaactga tacagaaagt
    48481 tttcattcag cccttagagc tattttgcgt caggacccag atgtaatact aataggagag
    48541 atgagagacc ctgaaactgt ttcaatagca ttaacagcag cagaaacagg tcatttagta
    48601 ttttcaacac tacatacagt gggggcagct aagacaattg atagaatagt agacatgttt
    48661 caaccatccc aacagcaaca aataaaaaca cagttatcta cagtttgtga aggtgtggta
    48721 tcacagcagt tacttcctac agcagatggg aaaggtagaa tagcagcaat tgaattgatg
    48781 tttgctactc cagcaataaa aaacctgata agggaaggca aaacatatca aattccaaac
    48841 atgatacaaa ctggagttaa agtaggtatg aaaactatgg accaagattt aatggaactt
    48901 tataaaaatg gaaagattac aaaagatatg gcacttagta ggtgtactga ccaagagttt
    48961 atgacaagaa tgataggtgg agtaaactac aatggatatt ataatcgtta atctatatgt
    49021 atttatagtg ggtatagtgt ttggaagttt ctttaacgtc tgtattttta ggattccaga
    49081 aggtatatct atttctagac caccttctca ttgtatgagt tgtaatacta gactaaagcc
    49141 aatagactta ataccagtgc taagctattt aatgagtggc agaaagtgta gatattgtta
    49201 tgagaaaatt tctagtagat atgctatagt ggaattaatt acaggacttt tatttttaac
    49261 agtatttatg ttatatggaa tatctacatc aactatttat tatttggttc ttgtgtcttt
    49321 actgattata attacattta tagatattga ccactttata ataccagata aaatattggt
    49381 ttttggagct atattttcta tgatttttaa ccttttattt aaagaaattc cagttaagga
    49441 ttcaattcta ggtgttttta tttgtggagg aagtgtctgg attatagttc ttttgattga
    49501 atttgtaata aaaaaagagt gtatgggtgg aggagatatc aaactatttg caatgctagg
    49561 actttacatg ggtgttaaaa atggtctttt gacagcctta ctaagcgttt atgtaggagc
    49621 agtctatgga atctgtgtaa taattataag tagaataaaa ggaaaggaat ataattctgt
    49681 tataccatat ggacctttta tatctattgg agcattaata acaatcttat ctggaaagca
    49741 attacttgaa ctttattttt ctatggttat atagatgata gtcaagttaa ataaagtttt
    49801 aatttaaaaa aatgaattaa agtatttaat aaggacaata ttattattaa ccctattact
    49861 aaagtgctac aaactatgga gtatataata ataatttcct tattttttgc acatttgata
    49921 aataaatctc tatgtgtttt ttgtgataga gaaaagaaaa atttatataa tacgtttttt
    49981 atttacataa taactgtagt tttatctgta ttaatatatc taaaatttgg gattagtgta
    50041 gaatgtgtac aatatatggt tttaattcca tttttaataa ttatatccat tgtagattac
    50101 tacacaatat atgtatatga tataacaata gttagtggta taatagttca aggtataatt
    50161 tttttggcct ttttcaatat agctcaattt gattatataa atcatatatt tggactattg
    50221 ataggcttta ttatacctta tattattgct aaactaacaa aaggattagg ctatggagat
    50281 gtaggtctct atagcttatg ttgctttgca ttgggaaata attatgggtt ttatgtgata
    50341 gttttatcat ttattttagc gtttttgttt tttattattt tatacataac taaaatattt
    50401 aaagatgtag atataagaaa gcaaattcct tttacacctt ttatttcctt gtcaacaatt
    50461 ttaataatat ttacagagta taatatattt aatttttatt ataatttgtt atacaaattt
    50521 atataacagg aggtaagaaa tgtacgtagt agtagggtta ggtaatccag gaaagaagta
    50581 tgagaagact agacataacg ttggatttga tgttatagat attcttgcta aagaatacaa
    50641 tattagtgtt actaaaataa agcataaagc tttgattggt gaagggagag taggtactga
    50701 aaaagtatta ttagttaaac cacaaactta tatgaattta agtggagaaa cattaataga
    50761 tatatataaa tattataagg ttgatttaag taatatagta gtagtatatg atgatataga
    50821 tttagaagtt ggaaagatac gtataagaaa aaaaggaagt ggaggaactc ataatggaat
    50881 gaaatctata actaagtgcc taggttcaaa tgactttcca agagtgagag taggtgtatc
    50941 taaaccagaa gctggtcaag acttagcaga ctttgtactt tctagattta gaaaagaaga
    51001 atctgataac ataaatgaag cattagaaaa agcggcagat gctattgact caataataag
    51061 agaaaatata gatatgtcta tgaacaaata taatggatag tgagagggag atttaaatga
    51121 atgatgtttt tttatatcct ttgcaaaatt caaaagagta taaagatata ataaactgta
    51181 taaaaaatac aaaaggctca ttattggtta atggactttt accagtacaa aaacctcata
    51241 tatcgtattc tatatttaat gatttatcac gacaaatgat ttttataacg agtagtgatt
    51301 tagaagcaaa gaaagtatac gaagatttaa gtttttatat ggaagataaa gttgaatatt
    51361 taggttttca agatatttat ttttatcact tggatgcaaa ggacagaaac gaagaagcaa
    51421 agaaattaaa agtattgtta aaactagcaa ataaagaaaa aatcatttta gtaacttcta
    51481 ttgaggcagt tttaagaaaa tacataccaa aacaagtttt gctcgatagt gtatctcatt
    51541 ataaggtggg agatagctta gacttagaaa agttaactga gaaattagtt tcattgggat
    51601 atgaaagagt ttcaaaaata gaggggtttg gtcaatttag tataagaggt ggaattattg
    51661 atgtattttc acttgaatat acaaatccaa ttcgtatgga attatttgat gatgagatag
    51721 attccatacg aacttttgat gtatattcac aaaaatcaat tgataaattg caacaattct
    51781 ctataactcc atctagagaa tttatttatc ccgaaaaaac tacagatgca ttagttaaat
    51841 taaaaaaaga aacaactaaa aatactgatg aaggtacatt tcaaaatata gattatatat
    51901 caagtaagac ttattttgaa ggtgcagaga actatataga ttatatttat ccagaagaaa
    51961 acaaaagtat atttacttat ttagcagatg atgcaatagt atttatcaat gatataacga
    52021 gacttaaaga aagatgcgaa aattatataa atgagtttag agaaaattat aaattaaatc
    52081 ttgaaagagg tctggctatt aaaaaccaag gtaaattgtt atatcactat acagatttag
    52141 agtacttagt aaaagacaag tctgtggtat taaactcgct attgccaaag tctataaata
    52201 acttttctat aaaatctata ataaattttg aaagtagaga agttcctaca tttaatggaa
    52261 aggtagattt gcttgtagaa gaattaaatc ggctgaaata taatggatac aaaataattt
    52321 tagcaacaaa taccttagaa agagcaaata aattaggaaa agatttattg gacaaaggct
    52381 tagaaacgac catttctaaa gatagagata ttgaaattaa atcttcacaa gttataattg
    52441 tacctgcaca cataaacagt ggttttcagt ataaatctat aaagtttgtt gttataacag
    52501 ataacgaaat gataggtgtt tataaaagag cgtctaagac tagcaataaa aaagttaaaa
    52561 agggaaagaa aatagaatcc tttttagatt taagtgttgg agactatgta gtccatgaaa
    52621 atagtggtgt aggtagatac acaggaattg aacaaattac agtcaatgct attaaaaaag
    52681 attatatgaa aatagtatat caaggtggag ataatctata tgtgccaata gaccagatgg
    52741 acaaagtaca aaaatatatt ggtgcagaag tagaaaaagt taagttaaat aagcttggaa
    52801 caaatgagtg gacgaaagca aaagcaaaag ttaaaaaaga aattgaagat atgacaaaag
    52861 acttgattga gctttatgca aaacgtgaaa aaatacaagg gtataagttt tcaaaagata
    52921 caccttggca ggcagagttt gaatcgttgt ttccatatca agaaacagaa gaccaattaa
    52981 aggctataga agaaactaaa aaagatatgg aatcaagtaa ggtaatggat aggctagtat
    53041 gtggagatgt tggttatgga aaaacagagg tagctattag aagtattttt aaagcttgta
    53101 tggaccaaaa acaagttgct gtattggttc caacaacaat attggcccaa caacattata
    53161 atacattcaa agagaggttt gaaaattatc ctttgagagt agaagtttta agtaggttta
    53221 aaacaccaaa acaacaaaaa cagattattg aagatgctaa aaaaggatta gtagatattt
    53281 taattggaac acatagaata atatccaaag atataaattt accaaactta ggtcttgtag
    53341 tcattgatga agaacaaaga tttggagtaa aacataaaga agctttaaag aaaattaaat
    53401 ctacagtaga tgtacttaca ctttcagcaa ctcctatacc aagaacatta catatgtctt
    53461 taagtggaat aagagacatg agtgttatag aagaacctcc acaagaaaga catcctgtaa
    53521 taacatatgt tacagagagt aaggaaagcg taattcaaga tgagatagag agagaattaa
    53581 gtagaggtgg acaggtattt tttgtataca atagagttga acacattgaa gaaatggcaa
    53641 gtatgattca aaaactcgta ccagatgcta gagtggctgt tgcacatgga agaatgactt
    53701 ctaaatcatt agaaaatata atcctaggat ttttaaataa agattatgat gtactagtct
    53761 gtactacaat aattgaaact ggtatggaca tatcaaatgc aaatacaatg attatatatg
    53821 atgcagataa aatgggattg gctcaacttt accaattgag aggtagggtt ggaagaagtt
    53881 caagacaagg atatgcatat cttttgtatg aaaaagataa aactttaagt gagatagcgg
    53941 agaagagatt aaaagctatc agagaattta cagagtttgg ttctggtttt aaaatagcaa
    54001 tgagagacct tgaaataaga ggagcaggaa atattttagg ttctcaacaa catggtcata
    54061 tggcagttat aggttatgat ttgtacgtta aaatgcttaa tgatgcaatt aaaaaagtca
    54121 aaggtgaacc tattgtggag gaaattgatg ttgaaataga tttaagtgta aatgcataca
    54181 ttccagataa ttatatcaaa gatgagttga ttaaaattga aatgtataag aaaatagctt
    54241 ctattgaaaa caaagaagac atgttggata tacaagaaga acttgaggat agattctctg
    54301 atatacctaa accagtccag acacttctta caatagctta tataaaatcg ttatgtaaga
    54361 tattaaaaat agaaaagata agacaattaa aagatgaaat attattagtt ccaataacaa
    54421 agtatagaac taaacagaaa ataggttata atatagttac agaattagaa gaattattag
    54481 aaaagatgtg caaggtaaaa taacttgtaa atttaagaag ggatgtttta aatttgaaaa
    54541 aagtaataac attggtaata gctatgattt tggtagtatc tgtgactgct tgcagttcta
    54601 gtaaaggaga aactgtggca acagttgaag gtacaaagat atcatcagat gaatttaaaa
    54661 aaactatagc tctttataaa gattctatgg aacaaactta tggaaaagat atatgggata
    54721 aggaagttga aaagggtgta aaatacaagg acaagtttaa agatttaatt cttgaccaac
    54781 ttataactac agaagtaata tattctcaag ctaaaaaaga taacttactt cctaaaaaag
    54841 aggatgttga aaaaagtttt aaagaattaa aagacgctat gggtaaagat gaaaaatata
    54901 aagaacaact taagaaatta ggtatagatg atgagttttt aagagaccaa caagagaaag
    54961 atttagcaat gcaaaactat caaagtaact ttgctaaaaa gactaaaata tcagatgaag
    55021 aaatgaaaaa atactatgat acacataaag atgaatttaa aaaagatgag gtagaagctt
    55081 ctcatatttt attgaaaaca gtagatgata ataacaagcc actttcagat aaggaaaaag
    55141 ctgaagctaa gaaaaaggct gaagaggctc ttaaagaagt taaatcaggt gaggattttg
    55201 caaaagtagc aaaaaaatat tcacaagata cttcagcaag tgatggtggt aaattaggat
    55261 tcttttcaag gggtcaaatg gttgctgaat ttgaagatgc tgctttttct atgaaaaagg
    55321 gtgaagtatc tgatttagtt gaaactcaat atggatacca cataattaaa gtgacagaca
    55381 gaataaatga gcaaacatca tttgaagatg ctaaagaaac tataaaagac caactgttga
    55441 aaaataaata tcaagaacaa atagaaaaat taactaaaga agctaaggta gaaaaagatg
    55501 aaaaagtaat aaataaaatc acaatctaag acttaaaaaa agagtaatat gcttaaaaaa
    55561 gctatatctg gataagatat agcttttttt gtatattttt cttaacaatg gtaaaaataa
    55621 acttaaagta atttatggag ggattaaaaa atatgaaagc aacaggtata gttagaagaa
    55681 tagatgatct tggaagggta gttatcccaa aagagataag aaagacatta agaattagag
    55741 aaggagaccc tttagagata ttcacagcaa aagatggaga agtcatactt aaaaaatact
    55801 ctccaatagg tgaattaaat gaattttcgc aagaatatgc tgaaacatta gctgaagtac
    55861 taggatatgg agtgttgata acagacttag attctataat agctgtatct aagcttccta
    55921 aaaaagatta caaagaaaaa agtataagtg atgagttaga agcaataata agtgaaagaa
    55981 cagtaaaata ttcaaaagat aaaaacattt taccattatt caaggaagac caaaaagaat
    56041 atactagtca agttatcatg cctataatta gtgcatctgg tgactgtata ggttcaattg
    56101 tagttgtttc aaaggataaa gatacaattg cagaaagtga agaaaaatct ttaaaaattg
    56161 ctgctaactt tttaggaaaa caagttcaat aattttatca taaagacctt ttacatgaag
    56221 gtcttttgaa gtttttgtgt aaaatattga atatagcatt aaaaatatgg tatattaaag
    56281 tttgttatat aaacagtatg gaggttatgt tatgaacaat aacaaaaata aagactcctt
    56341 tctaaaagga gcccttatac ttgggctagc aggtgtaatc gtaaaaataa tgggtggatt
    56401 ttttaggatt ccccttggaa acatgattgg ttcagaagga atgggatact atcaggctgc
    56461 ttatcctgtg tatactctat ttttaacatt agctactgct ggatttccaa cagctgtggc
    56521 aaaattggtt tcggaaaaag ttgcaattgg aaattttaaa ggtgcaaata agatatttaa
    56581 ggtatcacat acagttttat tcattaccgg tataatatca ttttgtatat tattttttgg
    56641 agccgactac atagtaacaa acgtaatgaa aaatccaggt gcgttatact ctatgaaagc
    56701 cattgctcca gcattactat ttgttcctgc aatgtctgca tatagaggat attttcaagg
    56761 gagacaagat atgactaaga ttgctgtgtc tcaagttgca gagcaatttt ttagagttgt
    56821 attaggtctt actttggcct acttgcttat gaagagtcta ggtcagactt ttggtgcagc
    56881 aggtgctata tcaggggcta caataggttc aatagcatct atgctttatt tggtgtttgc
    56941 ttatatgcta gggagaaaag agcgtagagc agagatagat gcaagccaaa gatttaaaga
    57001 tgaaagagtg tcttatattt ttaaaaagct tttaactgtt gccattccta taacaatagg
    57061 agcatcagta atgccacttg taaatatgat agataatgtt attgtaataa gaagacttat
    57121 ggaagcagga tttacataca aagtggcaaa ttcaatgttt ggtcaattaa caggtatggc
    57181 aatggccaca ataaatttac cagcagtcat aacaactgca atgagtatga gcttagttcc
    57241 agcaatttct aaagcatatg cattaggaaa taagtcaaaa gctagaaaag atactaagag
    57301 tgcagttaag gtaactttac ttatagtatt gccttgtgcg tttggtatgg cttctttagc
    57361 aataccaata atgggtcttt tatttccaca tgaaccatct tctgtaggaa ctattttgtt
    57421 tactcttact ccatgtgtat tatttttagg attaatacag acattgactg gtataattca
    57481 gggaatggga aaaccaatag tacctgtaat tgctttatgt gttggtatgc tatgtaaaat
    57541 tgtaataagt tatactttaa caggtatacc agatattaat gtactgggtt cagcatttgg
    57601 tacagttaca gcatactttg tggcagccat gattaactta ctatatgtta aaaaacacat
    57661 gaatgtaaac ttttctaaaa aagaatttat aataaagcca tttataacag ttatgacaat
    57721 gtttataatg gttaagttga gttatggtgc tttagttgga ttcttaggaa acagcatatc
    57781 tacaataatt gcaatatgtg ttggtggaat tgtatatgta gtagtaatac ttggaatagg
    57841 tggaattaaa aaagaagaga ttctaactat gccaaaaggt gataaattat ataaattgtt
    57901 aaaaaaagtt aaacttataa gataatatag gaatatatat gcaaataaag gaaatactat
    57961 acaaatagta aatctcctta tttgtataat aatataaaaa taaagtgaaa tttgctaata
    58021 ggagtgatgt tatgggtaag ataagtattg taggtcttgg accaggagac tattctctta
    58081 taagccaagg tgtgttagaa tctttaataa atagccctaa agtttttttt agaacagaga
    58141 aacatccaat aattgataaa cttaaagaaa ctatacaata cacttcttta gactactttt
    58201 atgaaaaaga ggaaaatttt gataatgttt atttgaaaat atctgaattt atcatagaag
    58261 aatcagcaaa gggtgaccta gtgtatgctg ttcctggtca tccaagagtt gcagagaaga
    58321 ctgtaagtat aatagagaga ttagccaatg aaaagcacat agcagtagaa atattgcctt
    58381 ctatgagctt tgtagacgct atgtttaact atttggctat agacccatct gagggattta
    58441 aactggtaga tgcttttgaa atagaaaatt catatataga cttggataca agcatgataa
    58501 taactcaggt atatgataaa tttatagcat ctaatgtaaa gttaaaactt atggaacatt
    58561 atgactataa tcaagaagta tgtatagtaa atggagcagg tgtcaaagat ttagaaagta
    58621 aaaagtttat aaagctttgt gaattagaca gaaatgaaaa cttttttgac tatttaacta
    58681 gcttatatat acccaaaagt tctaaaaaga tgtataatac agtacatgac ttagaaataa
    58741 tagttaatac acttagaagt ccatctggat gtgaatggga taaaaaacaa acacatcaat
    58801 cattaaaaaa ttctgttatt gaggaagcat atgaactttg taatgcaatt gataataatg
    58861 atatagatga aatggtagaa gagttaggtg atgttctttt acaggttata ttccattgtc
    58921 agataggaaa tgaggagggc tactttgatt taaaagaagt agtaaatggc atatgtaaaa
    58981 aattaattca tagacatcct catatattta gtggtgcaaa attagatatg tctaagtttg
    59041 agaaaacttg ggaagaatta aagaaagaag agaaaggcga aagtactata acagatggcc
    59101 ttagaaggat accaaaacat ttaccagctc ttatgaaggc tagtaaagtt caacataaag
    59161 cagcacttgt cggctttgat tgggacaatg tagaagatgt atttaaaaaa attgaagaag
    59221 aatatcagga attacttgac gaacacaggg tcgggaatat aaaatacata aaggaagagc
    59281 taggcgattt attattttcg atagtaaatc tagctagatt tttagacata gactcaggag
    59341 aagccttgaa ctgtactaca gaaaaattca taaatagatt tgactttata gaaaaaagtg
    59401 caatgaactt gaataaaaaa ttagaagaca tgacacttga agagatggat gagttttgga
    59461 atcaggctaa aaaacaataa aattgtggaa ggaaatttgt caaaaatcta gaacttttat
    59521 cacaaagata gaagtctata ttataaacat ttttaggagg taaatatcgt gaataaagct
    59581 gaattagtat caaagatggc agaaaaaagt ggattaacaa agaaggaagc agaagctgcg
    59641 ttaaacgcat ttatgagttc tgttcaagat gcactagtaa ataatgaaaa agttcaatta
    59701 gttggatttg gaacatttga gacaagagaa agagctgcta gacaaggaag aaatccaaga
    59761 gatccagagc aagttataga tataccagct tctaaagcac cagttttcaa agctggaaaa
    59821 ggattaaagg atataataaa tggataatta gaaatcttgt gaaaaagtgt ggataaattt
    59881 gccacacttt ttctatagaa ccaaggaagg tgataattat gagattagat aaatttttaa
    59941 aagtatctag gattataaaa agaagaactg ttgctaaaga tgcatgtgat aaagggattg
    60001 tcactataaa tggaaaagtt gctaaatctt cttcagaggt gaatattgga gatacattag
    60061 aaatacaatt tggagagaag aagatgaagt ttaagataaa tgaagtaaaa gagcatgtat
    60121 taaaaaatga tgcaaaagaa atgtacgaaa ttttagaata aaattaatag tcctctagta
    60181 tattaatagt agtattattg aaatatttac tggggggata ttatggaaca gaacataact
    60241 ttgaaagata gatcaaagct ggttatttcg ggagtcgagc acatatactc ttttaatgac
    60301 aaaagagtag agctcaaaac ttctgtaggc gagatggtaa ttgaaggcga aaacctagat
    60361 atgagcaagc taagtataga cgaaaatata attagcatag atggaactat aaattctatg
    60421 gtatatgcaa agcctaaaaa gccacaagag agtttcttga aaaaggtatt tagatagatg
    60481 atacctttta ctcaagatgt aagcattttt tatgctacta tttatggtgg aatactcata
    60541 ggggtgttgt ttgattttta tagagggcta agagggaatt ttaaattcat caattatttt
    60601 gctataatct ttgatgtatt gttttggttt ctagctacgg ttataatatt cgtaacaata
    60661 aaccttacag aattttttga tttaagatat tatcattttg tggctttgtt tattggtttt
    60721 attttatact ataacaccat aagtaaaatt gttttatcaa ttatcaataa aataattcgt
    60781 tttgtgagaa attcttttaa aaaagttaca cactacatag tcagtttttt aaataatttg
    60841 tattacgtta taatctattc actacaccta ctatttgata ttatatttta tataccaaac
    60901 atatttatag caacaagaaa aagtataaaa agaaaatcaa ataaaaaatt aaagaacaag
    60961 aaaaaatcaa aacctaagaa gaaaaaaaat aaaactaaaa aaagggtgta ggaaaaatga
    61021 acttaagaaa aaaattttca ggacagatta ttgttatcag tttattttta ggaatatcaa
    61081 tttttagtat gatgacagga tttgtatttg agtatacaaa agctaaggaa tataaaaaag
    61141 aaatagcaag tctaaataaa caattaaaaa agactgaaat acaaataaac agcttaaaga
    61201 aagatgaaaa atcatatgaa ggagacttag aggatatagc aagaaaaaga ttgaatatgg
    61261 taaaaccaaa tgaaacagtt tatgtagaca taaatcgttg attaaaactt gctaataagt
    61321 ttacagatgt attgatttta aaatttaaga tttaataaaa aagtcattca gttaaggatg
    61381 gctttttgtt tttattgagg agggaatttc ataatgaaag taggagctat agatattggg
    61441 acaaactcaa tgagattatt gatagcagat tatagagatg ggaattttat aaacagaaaa
    61501 aaatttgtta atacaactag aattggttat ggtgtggata gtaaaggata tataaaagaa
    61561 gatgctatca aaagaaatat aaaagcatta aaagaatttt ctgataagtg taatgatgaa
    61621 aagtgtgaaa aaatttattg tatggggaca tctgctctta gagacagtaa aaatggagat
    61681 tactttgtta aattagctaa agaagaaact ggaatagatg ttgatatagt tacgggaata
    61741 gaagaatcaa atttgggctt taagggtgtt ttagaaggaa tacaaggtga tgatactatt
    61801 attgttatag atattggagg aggttcaaca gaatttattg taggtgattc agaaggaatt
    61861 atatttaata aaagtgagaa tgtaggtgct cttaggatga cagagaggtt tttgaagcac
    61921 gatattattg aagatgaaga gtttgaagct atgagttcat ttatatatgg tgagattgat
    61981 aaaacgttaa atcatataaa agacagagga ttaaaaactc ttataggtat aggaggtacg
    62041 attacatcat tatcagcaat gaatcaagaa ttagagattt actctatgga aaaaatacat
    62101 aatagtaaaa tacacaaaaa agaaatagaa gaaattctac aaaaattaat aaagatgaca
    62161 ttaagtgata aaaagaactt aaaagggcta caagaaaaac gtgcggatat tataactgct
    62221 ggtgtaaaaa tattgaatat aataatggaa aaattagaaa tagaagaaat aaccgtaagt
    62281 gaatacgata atttggaagg cttaatatgt caaaagtcaa aaaaaatgta ttaatatttt
    62341 ttgattttta aaaccgatta tgacaaaaaa aattactcct ctttgttaca attcttaata
    62401 taaacaaaag aggaggtttt tttatgcaaa gaagtgtagc agttgtgaag aataagactg
    62461 taaaaccaaa tgtcataaaa ttaataagcg gatatattga ttttactacg gcggcattcg
    62521 ctgtgatggg atttttactt agtaggtcta ttatagtaga ctctgtagct cctttaggaa
    62581 ttgccttttt tatatgtgca tcaaagattg ataagtacaa gatacctgta ttcatatcaa
    62641 cattattagg aatattgtta tcatctaatg attttggaaa tgtagcaaaa tatgctgtgt
    62701 gccttacaat atttatggct atgaataaaa aattaaaatt atcagattca attgctaagg
    62761 ttgcatttat aggtgcaata atactacttc caatctccat gggacaagct ttcttttcaa
    62821 ataggtatgt atatggtctt cttatagcag gagtagaagc aataataatg tttatatcta
    62881 tatatgtgtt ttcttatggg ataggtttaa tggccaatgt caacaatagg atgtctgtac
    62941 ggacagaaga agccatatca ataagtttac tgctaacctt tagcataatg ggaataggag
    63001 atatatctct gtttggaata tcaataagga ccattttatc gaccgtattg atattgctga
    63061 cctcaatagt aggtggagct accatgggag catctagtgg tgtaattatt ggtgtagcat
    63121 ccattttaaa taatatgaca tcagctgttt atatggggat atattctttt tcaggattaa
    63181 taagtggagc atttaataaa ataaataaat atttctgtat actaggatat attctaagtt
    63241 ggacaataat atacctatat acttctggta ttacttctaa tatgatgcaa ttaagagata
    63301 tactattagg ttgtttgata gtactagtat tgccagagcg attatttaat aagattgaaa
    63361 aattaataaa aagtaatgtg gcttcaaatg aaatcgtata cgattatatt atgagaagca
    63421 aaaacctaac taatagcaga ttgaacagta tttataaaac ttatgatgac cttgcagata
    63481 catttgataa gataagagaa aaagacaaag tgctagacca aagagacata gctaatgtaa
    63541 tagatatgat tcataatgat gaatgtaaaa gttgtagtat gagaagaatg tgctgggagt
    63601 caagatttaa tcatacatac actatgatat ataacattct tgaaaaaatt gaggagaaag
    63661 gggagttaag tctaaacgat atacctaaaa attttagaaa ggaatgtatg aaaccagagt
    63721 caatagtgaa aatatcaaat cactattaca aaatgtttgt attagattat gattggagtg
    63781 tgaagttttc agaaagtaga aagttaatag caaatcagat aagaagtatt tcaaaatcca
    63841 ttaaatcctt atctcaagat ttagaaggcg acataatgct agatatagaa aaggaaaaaa
    63901 atatatatga acagttagaa agatatgata taacagttga taaagtaagt tacttaacaa
    63961 aaagtaacag tgagtttgaa atatcaatag aaaagaaaac ttgccatgat ggatgtatgt
    64021 gtgaagataa aattgtaaat ataatttcag acctagtagg ggaaaatatg tctgttagaa
    64081 aaataggatg tcactgttta ggaggtaaat gcaaggcaac attcgttaaa tctcaaaaat
    64141 ataaggctgt tacagaagtt tcagcaatgt caagggatgg gcatatcctt tgtggagaca
    64201 attacacata catggagata aatgatggta aatacatgat ggctataagt gatggtatgg
    64261 gaaagggtaa aaaagcatat gaagaatctt ctgccactat tgatatactg gaaaaaatga
    64321 tagatgcaaa aattaaagat gagatagtca ttgatactat aaacaatatg ttgttgttaa
    64381 aatcttcaga agagatgttt tcaactctgg atttgggaat tttagattta aaacgaggtt
    64441 gtttagaaac tataaagatg ggagcgtgtt ctacttatat aaaaagagag gatggagaag
    64501 ttgacttaat atcatcatca tcattacctg tgggtatatt atcagatgta aaaattgata
    64561 gaaaaaatgt aaaagttaag gaaggagact atgttataat ggtttctgat ggaattgtag
    64621 atgcaggaag aaataacaat ttaggagaca attggttaat atacttctta aagaatatag
    64681 agactacaaa tccaaaggaa atttcaaatt taatattgga tagagcatta gagttacaag
    64741 cgttacaaat cgaagatgac atgactgttt tagttacgaa aatatgtaca aaataaggtt
    64801 tacaagatta tgtgtataag atgtggataa cttgtgtata atatgttaat agacttttga
    64861 aaaaagtata gttattaaca aaaataacat ataaatcaac aaaatttgtt gataagtatg
    64921 gcagaaatgt taataaaatg taaaaaaaga aaaaacaaaa gctattatca aaagagattc
    64981 atgttgaaat aactaaattt ctaagtaaag aaaacctgtg aatatgttga ttattatgtg
    65041 gataactatt aattcgatat ttatttatat agtatgaata attgaataat atatctaaaa
    65101 aaagccatcc tattattaag taaacttatt gaaaggatgg ctttttatga atagaaaatt
    65161 gtgcaaagca ataatacctt tatttatttc tattttttgc atgttaataa taagtataaa
    65221 agctgaccaa ggatatcaaa agaataatga cagagcaatt actgtcatga ataataatga
    65281 tactgaagat gatgctgaaa aaaaacaaga aatagactat gaaaaaacat gttggaattt
    65341 gcaatctttg tttaaaagtg atgaccaatg gaaaaaagaa cttaagagtt ttgataaaga
    65401 tactaaagag ttgaaaaatt acataggtaa agtaacaaaa tcgccaacac atttgtcttt
    65461 tgccttaaac attaaagaaa aacttgatat aagactaaat aaactttctg cctatgtaaa
    65521 attaaaacaa gatactaata aaaattcgta taagtactta gatatgaatg atagtatgag
    65581 taaatcctat gggaattata tggggatttg ttcagattta gagttagaaa tactaaaatt
    65641 atcaaacaaa gattacaaga aaattatttc aaataaaaat ataaatagga aatatggtgc
    65701 atatttaaga gatataagaa ggaataaagt acattatttg gatgataaat cagaagatat
    65761 tctaagcaaa gtatcttcaa taagtagtct tccaagccaa gtgtatgaat tatttagaaa
    65821 tatggataga aaaactaatt tgacaccagc tcaatatgcg agtgaattag agtcatcaga
    65881 tagagaaaat agaaaaaaag cttatcaaga tgaacttata acttacaatg ataatataaa
    65941 tacaattgca ggtttaatta ctggtcaagt taaaaagaat attttttatt ctcaggaaag
    66001 aggttatgag tcttctttag aaatgtacct ggaatctgat aatgtagatg aaaaagtata
    66061 caataatttg ataaggactg taaatagtaa tatggacagt ctacacaaat atatagattt
    66121 aagaaaaaaa gtattaaaat tagataaggt tcattcatat gatatgtttg tgcctatggt
    66181 taaggctgtt gataataata ttaattatga aaaggcacaa agtatagtat attcagcgtt
    66241 gtcaccttta ggaaaagaat acaatgatgt agtatataaa gctttcaatg aaaaatggat
    66301 agatgtttat tcacatgaaa ataaagtaag tggtggatac tgcttatctg tttatgaaaa
    66361 tcatccatat atacttttaa attataataa ttcattaggt tcagtttcga ctttatcaca
    66421 tgagcttgga catgctgtat atgaatactt aagttctaag aatcagaatt attttaattc
    66481 aaatccgtct atatttactc acgaagttgc atctacaacg aatgaagcat tactttacga
    66541 gatgcttata aaagaagcta aaggcaatga tgaaaaagct tattatataa cacagtattt
    66601 agacttgata aaagatactc tttatacaca aactatgtat gctgaatttg aaaaaactat
    66661 acacgagtta gtagaaaaag gaaaaagtgt aaacgcatta gtattaaatg atgtttgggg
    66721 acaacttctt aaaaaatatt atggacaaag ctatgaatta gaccaattat ctaaggtcgg
    66781 atgggctaga atcccacatt tttataatag tttctatgtc tataaatatg ctacaggttg
    66841 tagtgcagga gtaagttttg cccaagacat cctaaagaat ggttcagata actatatgag
    66901 ctttcttaaa aagggaagtt cagattatcc aataaacttg ttaaaatcaa gtggcataaa
    66961 tttaactaat acaaaaccca tagaaaatac aatcaaaaaa tttgatagtt tagtagcaga
    67021 acttgaaaag ctattataaa cattattgta atccacatgg taaatatatc gaattaatga
    67081 taaaatatac taaaagttta aagtcctatc aagataggac tttttattta ttaattagtg
    67141 ggagatgatt ctatgcaagt taaagttaaa aaggctgtaa taccagcagc aggtttagga
    67201 actagatttt tgccagctac aaaggcacaa ccaaaagaga tgttaccaat agttgataag
    67261 ccaactctac aatacataat agaagaagct gtggcctcag gaatagagga aatactaata
    67321 ataacaggta gaaataaaaa atctattgaa gaccactttg ataaatctgt agaattggaa
    67381 cttgatttag agaaaaaagg taagaaagaa ttgttggagg tagtacaaaa catatctaac
    67441 atgattaaca tacattatat aagacaaaaa gagccaaaag ggttgggaga tgcaatttat
    67501 tgtgcgaggc attttatagg tgatgagccg tttgcagtaa tgttagggga tgatattgta
    67561 gataatgatg taccttgtct aaaacaacta acagatgcat atgaggaata tagaactaca
    67621 atattgggtg ttcaaaaggt aaatcaagaa gatactaata aatatgggat aatagaagca
    67681 aaaaatatag aaggtagagt ttacaaggta aaagacatgg tagaaaagcc agagtcagga
    67741 aaagctcctt caaatattgc tattttaggt agatatataa taactcctga aatctttgat
    67801 attcttaagg atttaccacc aggtaaaggt ggagaggtac aacttacaga tgctttaaaa
    67861 atattatcta agaaagaagc tatgtatgca tacaattttg aaggcaagag atatgatgtt
    67921 ggggacaagc taggattttt agaagctact gttgactttg ctctaaagaa agaagacctt
    67981 aaggaagatt ttataaaata tttgaaacat gtatgtagtg aatttgataa aaataacaat
    68041 gtgttataca ataatacaga tgaaaaaata gatttaattg aagtcaatga agctagagaa
    68101 cttgaaattc aaaaataatt aatgaaaggt gatgtatggt ggcaaaatca agtcagaaaa
    68161 gaattaatag aataatagct gttgggattg tgggaatcct cgtaataacg agtataacag
    68221 ctgttttgag tatgattgca actatgtaat aagataaatg acagcagttg atatacataa
    68281 atataaaaac catatataac ttgatgtagt aaaaaactta caatatttta gttatatatg
    68341 gtttttagaa tttataaatg taaaaaaaaa tttttataat agttgcatat tttaaaggaa
    68401 aatattatta taagatataa atatagtgat aaatttataa aaacgtgcta agattggact
    68461 tgaaatacag taatatagta ggtaataatg ttttaaattt tatttattga ccataatata
    68521 taaataatga tattattaga cttaactgtt taaataaaac ttttcttttt catgccttca
    68581 atttccaaaa taagtatgta tataaatgaa tatatagatg aggaggattt ttttgatttt
    68641 agatgataaa gtattagaag gattaggtag taagacctta gttgagctac gagagatagc
    68701 taaagaatta aaaataaaat caattactac atataagaaa aatgagttaa ttgagattat
    68761 aaattccaaa agtaaaaatg aggaaaaagt aaacgaagag actaaagaaa aaaatgaaga
    68821 tattaaagaa gacataaaga atagaaaaga aaatatagag cgtgaaagta tagaaaaaga
    68881 agttgaatat aagagcccta ccaaatcata caacaagaaa gaaatagata cccaaaatat
    68941 ttcccaaaac caagaacata gaaatcaaag aaatgactat aataagacaa cgagtgtaaa
    69001 tgatagcaat aagtcatcaa atatatctaa tagaatggtc agaaataata ataaaaacta
    69061 ttatatgcct aaacaagttg atgaatctaa gatagtagat gaatttaaca catcaaaaga
    69121 ggatgaagta gtaggtgtac ttgaaattct gccagatgga tttggttttt taagaggttc
    69181 aaattatttg tctactgaag gagatgttta cgtttcacca tctcaaataa gaagatttaa
    69241 tatgaaaaca ggagacaaga ttaagggaat aactagacat ccaaaaagtg gagagaaatt
    69301 tagagcactt ttatatgttc aaaaaataaa tgatgaaaac cctgacacag ctatacaaag
    69361 aaatgcgttt gagacattaa caccaatatt tccagaagaa cgacttacac tggaaactaa
    69421 tagaaatgaa atagctacaa gaattataga tttaatttca cctataggaa aaggacaaag
    69481 aggattgata gtagcacctc caaaagctgg gaaaacagtt cttttaaaaa gcgttgcaaa
    69541 tagcatagct aaaaatcatc caaatgttga acttatagta ctccttatag atgaaagacc
    69601 agaggaagtt actgatatga aagaatctat tgaaggagac gttatatatt ccacttttga
    69661 ccaagtatca agtcatcatg tcaaggttgc agagatggtg ttaaatagag ctcaaagatt
    69721 agttgaacat ggtaaagatg tagtaatttt actagatagt ataactagat tggcaagggc
    69781 atataacctt acaatatctc ctacaggtag aactttatct ggaggtattg accctggtgc
    69841 acttcatgga cctaaaaagt tctttggtgc agcaaggaat attagacagg gtggttcttt
    69901 gacaatatta ggaacagcat tggttgaaac tggttctagg atggatgatg taatatttga
    69961 ggaatttaaa ggtacaggaa atatggagct acatttagat agaaaattag cagaaaaaag
    70021 aatattccct gcaatagata tttacaagtc tggtacaaga agagatgatt tattgcttga
    70081 tgatgaagaa aagactgctc tttggagatt aagaagagaa atgagtaata attcagtaat
    70141 ggaaattaca gataaagtca ttgaacttat aaagagaact aaggacaata aagagtttgt
    70201 aaaatcaata aagaatttgt aaaatcaata atacaaatgc aaatatggat tatataaact
    70261 aatagaaaaa tcacttgaat ggcataataa gttgtgctat aataatgtag ttgataatgt
    70321 aaaaagaaag ttaatataat taattttttt aaataaagag aagaggtgac tataatgcaa
    70381 aaggaaatac aaccaaaata caatccagtt gaagtgcgtt gtgcttgtgg gaacacattt
    70441 gttgctggtt caactaagga cgaaataaaa gttgaaatat gttcagagtg ccatccattc
    70501 tatacaggaa aacaaaagaa catagaaaaa ggtggaagaa tcgacaaatt caagaaaaga
    70561 ttcaaaatgg actaattttt ataaaagtgg agttggagga agccaactcc tattttatta
    70621 caaaaaaaca ttcatattct actttaaatt gtctttttgt attataataa taaatatgta
    70681 aaattgagta ttctaaatac aataaaatga ggtgagtgga tggcaaaaca agctgtaggt
    70741 gggcaagctg ttattgaagg tgtaatgatg cagtcaaaag acaaaagagc ggtagctgtt
    70801 agaaaaagtg acggagaaat agcactaaaa gaagatagaa taaaaagttg ggtaagagat
    70861 aagaatatag ataagatacc ttttgttaga ggttcttttg ttatgataga tacaatgatt
    70921 caaggcataa aaagcttaaa cttttcttca gagtttttta tggaagaagc tgaagaggat
    70981 aaatttgatt tatttataaa gaaaattttt aaagataagg caaatgatat aattataata
    71041 ttttcattgg tcatagcaat gttactttct gctggattat tcatttttat acctacattg
    71101 gtaggaggag ctttttctaa agtaatgcct aatgatttta tgcttaattt aatagaagga
    71161 atcataagga tagctatatt atttgcatat atagtattga tttcacgaag taaggatata
    71221 gaaagagtct ttcaatatca tggagcagaa cataaatcta tatattgcta tgaaaatgat
    71281 ttagaactta cagtagagaa tgctagaaaa tttaaaagat tacatcctag atgtggtaca
    71341 aatttcctat ttatagttat ggctgtatca ataatattgt ttgcattttt tggttggcca
    71401 aatccaattc ttagaatatt tatgagaatt atatgtgtgc ctatagtagc aggtttatct
    71461 tatgaggtaa ttagagttct tgggaaatat gataatggat ttactaaaat tattgcatat
    71521 ccaggaatga tgttgcaata ttttacaaca aaagagcctg atgatgagca attagaggtt
    71581 gctttggaag cattgaaagc agtagtagat tagagaaaag gatatttgtt atgacgataa
    71641 aagatataat tattaaatat tcagataaac taaaagatat aagtgatact ccaagattag
    71701 atacagagtt attgttacaa aaaacattgg gtgttgatag attatatatt cacttaaatc
    71761 tgaataaaga gctaactgaa gaacaaaaaa caaaatttat gggttttgca gaagaaagat
    71821 taaatggaag accaatagca tatatagttg aaaataggga gtttatggga ttagattttt
    71881 ttgttaagga aggcgtattg attccaagac cagatacaga aactttagta gaagaaataa
    71941 ttgaaatatg tagagaaaaa aaagatgtaa gtatattaga tataggaact ggttctggag
    72001 ctattacaat aagtttagca aagtacattg aaaattctaa aatcatgtct tttgatatat
    72061 cagagacagc attagaaata gctaaaaaaa atgctattat aaatgaagtt ggtgaaaaaa
    72121 taaagtatat taattctgat ttatttacag caataagtga tagtaacata aaattcgata
    72181 tcatagtttc aaatccacca tatattaaaa aacaagatat agaaactctg cacaaacaag
    72241 ttaaagatta tgaaccatat aatgctcttg aaggtggaga agatggatta gacttttata
    72301 gaagaataac agaacaaggt aagaaatatt taaataagtg tggaatatta gcatatgaag
    72361 ttggtcataa tcaagctgaa gatgtaataa atattatgaa aagtaatgga tataaaaaaa
    72421 tatacacaaa gaaggatatt caaggcattg atagagttgt tataggttac aatatatgat
    72481 ataatcaaca attgatatgt tacatttaat cgaggtgaaa gtatgttaaa aaaattagag
    72541 gtattggaag atacatataa agacttaagt gaaaaaatag gtgatccgga tgtaataaat
    72601 gatcaaaaag tttggcagaa atatataaaa gaacatgctg acttggaacc tattgttatg
    72661 aaatacagag agtataaaag cgttttagat agtataaaag aatcaaaaga aattttacaa
    72721 gaagagtcag atgaagaatt aagagaatta gctaaaatgg agttagctga gatggaagaa
    72781 aaagtagcac ctctggagga agaaataaaa atactattat tgcctaaaga ccctaatgat
    72841 gataagaacg ttatagttga aattagaggt ggagctggag gagatgaagc agctctattt
    72901 gctggtgatt tatttagaat gtactcaagg tatgctgaaa gaagaagatg gaaaatagaa
    72961 ttattgagtg caagtgatac tggagttggt ggatataaag aagtatcttt tatgataaaa
    73021 ggtaaaggtg cttattcaag attaaagtat gaatctggag ttcatagagt tcaaagaata
    73081 ccatcaactg aatctggtgg aagaatacac acatcaactt ctactgttgc agtattacca
    73141 gaagttgaag atgtagaggt tgaaataaat ccaaatgatt taagaataga tgttttccgt
    73201 tcttcgggta atggaggaca aagtgtcaat actactgact ctgctgttag ggtaacacat
    73261 atacctacag gtgaagtagt atcttgtcaa gatggaaaat cacaattaaa aaataaagag
    73321 caagctttaa aaatattaaa agctagactt tacgataaag cattggcaga acaacacaaa
    73381 gatatagcag cagaaagaaa aagccaagtc ggaacaggag acaggtcaga aagaataaga
    73441 acatataatt tccctcaagg tagaataagt gaccatagaa taaatttaac tttatataag
    73501 ttagatgcat tcttagatgg agatatagat gaaatgatag atgctttaat tactgttgac
    73561 caaacagaaa aaatgactgc aatataagta atgttttaaa gaagctgttt cttcctagaa
    73621 attattttct attttgaaac agctattttg cattttaggt catgttatca tattctattg
    73681 tatataattg ttatatacaa gtataggagg gttatatgat actaaaagta acaataattg
    73741 ggcttttggc aggtgttata gggacaggat taggaggagt aatatcagcc atttttaaaa
    73801 gagaggtcga taaatatcta agttttttta tgggattatc tggtggaata atgttggctg
    73861 tagtggtgtt tgatttaatg aaagaatcca tggacaaaat ggggataatc aatacagtta
    73921 tatttacgtt tgttggagct ctcataacta tgtacataaa aacaaaatta gatgtgtctg
    73981 gaaatatggc atctggatat cttatattca taagtatatt actacataat ttaccagaag
    74041 gactagccat tggttcttct tttatgtcaa ctgaaagttt aggtattaca cttgctatag
    74101 ttataggtct acataatata ccagaagggt tagctatggc attaggctta gtttgcaata
    74161 aaatgaaact aagtaaagtt attttgttta ctgtaatagc tggattacct atgggtctag
    74221 gaagtttttt aggtgtttat tttggaggag tatttacttc tcttatagga gtatttcttg
    74281 ctacagcagg aggtactatg atgtatgttg tattggaaga aatttttcca cattcaaaaa
    74341 gtgtgtattg tataattggt ttcttgttag gtacaatgat tgtaaattat atataaaatt
    74401 aaaatgaaag caggcataca aaagatgaaa actattataa gtaatattga tataaataat
    74461 attgattatg aggaaataaa aatacaagca aaacttctta gagaaggtaa aacagttatt
    74521 tttccaactg agacagtata tgggttgggt gcaaatgcat tagatgaaaa tgcagtaaag
    74581 aagatttatg aagctaaagg aagacctagt gacaatccat tgatagtcca tatatatgaa
    74641 aaagaagaag tatatgactt agccaaagat ataagtgata aagctaaact tgttatagaa
    74701 aagctttggc caggacctat aacaattata ttaaataaaa aagatataat tccatacaaa
    74761 actagtggag ggcttgatac agttgcaata aggatgcctt ctaatgttat tgccagggca
    74821 ataataaaag aagctggtat acctattgca gctccttctg caaatatctc aggtcgccca
    74881 tctccaacaa aagcaaaaca tgtatatgaa gagatgaatg gaagagtgga tggaatagtt
    74941 ttaggaggag acagtaattt tggattggag tcaactgtat tggatttaac agaagagact
    75001 cctatgatac tgagaccagg aagtataact aaagaagttt tagaggaact tcttggagaa
    75061 gtaaagcttg acccatcatt aagtaaaaaa gaagataatc aaaaagctaa agctcctgga
    75121 atgaaatata aacattattc tccaaatgca gatgtatata taatatctgg aaaaagagaa
    75181 aatgtagcat caaagattaa tgatatgata aaatctaata gagacaaagg tctaaagaca
    75241 ggtgtaatgt gtattagtag aaaccgagag ttttatgatg gagaagtaat cgatttagga
    75301 aactctcttg aagaagttgc aagtaatctg tttgatgctc ttatagaaat ggacaaaaag
    75361 ggtgttgatg tcatatattc agaagagttc cccaagactg gagttggaca agcaattatg
    75421 aatagactac tgaagtcagc aggatacaaa gtgataaagg cttaagaggg agttgtaaaa
    75481 tatgaatata cttattgtgt gtacaggtaa tacttgtaga agtcctatgg ctgaggctat
    75541 actaaggaaa gcaattaaag aatctggaag aagtattgaa gaatattcta tatcatcagc
    75601 aggtatatct acagcaaatg gaatgggtgc ttctgaaaat tctatagaag tactaaaaga
    75661 aatcggtata gacttatcaa atcatagaag taaagtaatt actaaaaaat taattgatga
    75721 atcagatata atactaacaa tgactaaatc tcataaagaa attttagtac aagcagttcc
    75781 aaaatgcaaa gaaaaagtgt atacttttaa agggtttgca aataaaaatg aggaagatat
    75841 atctgaccca tttggtggaa atttggatat ttatagaagc actatgagag aaataatgta
    75901 ttctgtcaac gaaatagtaa aaaaaatatg aaacggagga taaacaaatg aagataggat
    75961 taggctgtga ccatggagga tataatttaa aaaaagaaat aataagctat ttagaaagta
    76021 aaggtataga gtgtgtagat tatggaacta ataatgctac agattctgtt gattatcctg
    76081 tttatggaga aatagttgca aattcagtta taaataaaga agtagattat ggaatattat
    76141 gttgtggtac agggatagga atatctttag ctgctaataa ggttcctggg ataagatgtg
    76201 cagttgtatc agatgtattt tctgcaaaaa tgtcaaaagc acataatgat gcaaatatgt
    76261 tatcattagg cgaaagagtt ttaggaaaag gtctagcact tgagatagtt gaagcatgga
    76321 ttaatacgga ttttgaaggt gatagacatg ctagaagagt aaacatgatt aaatcaatag
    76381 aagaaaaaca taataaataa taaaaattac agttttatca ggaggaatta tcaaaatgag
    76441 caaagtggta gagacaaacc atccattaat acaacataaa ttaactttaa tgagagataa
    76501 aaatactggt tctaaagact ttagagagct tttaactgaa attgcaatgt taatggggta
    76561 tgaaataaca aaagatatac cattaaaaga tgtagaaata gaaactccta ttcaaaaaac
    76621 atcatctaaa gtagttgcag gtaaaaaatt agcaataatt ccaattttaa gagcaggtct
    76681 tggaatggta gatggattag tgagcttaat gccagcagca aaagttggac atgtaggact
    76741 atatagagac ccagaaacat taaaaccagt tgaatattat tgcaagcttc ctcaagacat
    76801 aggagaaaga gatataatag tagttgaccc tatgcttgca acagggggtt ctgctgtagc
    76861 agctatagat ttacttaagt ctaaaggagc taaaagtata aaattagcta atttagtagc
    76921 tgcaccagaa ggtatagcag aagtgcaaaa atatcatgat gatgttgata tatatgttgc
    76981 atcagttgac gaaagattaa atgaacatgg atatataatt cctggtcttg gtgatgctgg
    77041 agatagattg tttggaacta aataaaaata aataactata aatatttatt agggactttc
    77101 ttatatagtg tatataattt tatgtaagaa ggttcttttt tatatatttt ttctcaaaat
    77161 aggaattatt gaattgataa atttctcgaa ttgagaataa aaagttttta ccaattaaaa
    77221 aagattgctt attttacaag attttataga atagtagtct attttaatgt ggcatgttag
    77281 ttgcttacga ttaagattat aggtattaag tgtattagtt aaattgagaa ttgaatatta
    77341 ataatattat tgggagtggt aatacatgaa gaattgtata gtagtaagag gggctggaga
    77401 tttagcaaca gcagttattc ataaattaca caacagtggt tttaaagtag ttgcgttaga
    77461 aatagaagag ccattagcta taagaaggca aatttctttt tgtgaggctg tttatgaaaa
    77521 aaaagtaact gttgaaggtg tagaatgtat attttgcaat actgaaaaag aaatagaaga
    77581 agttttatct caacataaag tagccttgat tatagaccca aaaggagaaa aattatctaa
    77641 attaaatcca atcgttttgg ttgatggaat actcgctaag aaaaacttag gtacaactaa
    77701 agatatggca ccacttacaa tagctttagg tcctggattt tgtgcaggag aagatgtaga
    77761 tgttgttata gagacaatga gaggtcataa tctaggaaga ataataacta atggtagagc
    77821 agaaaaaaat acaggagtac caggagcaat aaaaggtttt tctaaagaga gagttatgca
    77881 ttcacagtat gatggcataa tggaaaatgt atgtaagata ggtgatatag ttgaaaaggg
    77941 agacctactt tgctatatta ataattatga aaaaaaacat gaagttagag caacaatatc
    78001 tggagtcctt agaggtttat taaaggatgg agcaaaggta aacaaaaatt taaaaatact
    78061 agacatagac cctagaaaag aagaagttaa gaatgctttt acaatatcag ataaagctag
    78121 atgtatagct ggaggggttt tagaagccat actaaacaat gggatttatc cccaaaatta
    78181 atttatatta gataaagcta ttaatatttt attaagatga tataataaat ttaatagatt
    78241 aaagagagca tatgacgggt atttaaaatt taaatggtaa aaatgctctt tttttattgg
    78301 acattcaatt aacatgtgta tataatataa aaataagtat ttatttaggt tgaaatctaa
    78361 taaatatata ataccagtac ataagcaaag aggagaaaag taaattatga gaccatcatg
    78421 ggatgaatac ttcatggaaa ttgcagaagt agtgaaaaag cgttcaactt gtattagaag
    78481 acaagtagga gctgtaattg taagagacaa acaaatatta acaactggat ataatggttc
    78541 tccgagaaat cttgaacact gtgaaaatat tggatgtaag aggcaggaat taaatattcc
    78601 ctcaggagaa aggcatgaat tatgtagagc attacatgct gaacaaaatg cgataataca
    78661 agctgctcat aatggtatta gtgtagatgg ggcaactttg tatgttacta caagaccttg
    78721 tgttttgtgt gcaaaaatgt gcataaatgc aggtatattg aaaattgttt atgaaggtga
    78781 ttatccagat gatatgtcta cagaattatt aaaagaagca ggaatagaac tcataaaatt
    78841 ttagtggata aaatttataa gacaataaat gtcaaattat gacactgaaa tacaatggta
    78901 tcaaatgatt aaaagaaagt atttgaaaaa tcatcagatt agtagtaaga tatattttat
    78961 aattaaataa atttatgaga tagattaatt acatgttatt tattttataa taatgaggga
    79021 tactatttat gagtaaaaga aatacacata cagaaattgc aaagttgttt agtttaataa
    79081 gtcaaatagg attgatgatt gtaatatcaa tattaggatg tactttctta ggaaaatttt
    79141 tagatagtaa attgaatact actccagttc tgacaataat atttttattg ttgggtgttg
    79201 gaggtgcttt tagtggtgtt tataaaactc taatagtata tacacgaagg aagtgatata
    79261 ttggatataa aattacttaa ccaggtaagg tcagtaacaa aaggtatagt aatatttgat
    79321 gtagttttaa ttgtgctaat gttgataaca tcaacattaa gtaaaccagt attattagga
    79381 cttatatttg gctctataat agctatgtta aattttagat tattggcgat atcactggaa
    79441 aaatcagtga catttcctgc tgggaaggca caagcttatg catcagcaca atatgctgtt
    79501 agattattta taatggcagt tgttctaatt gcatcagcta cagtaccaca tttaaatata
    79561 atcggaacag cattgggatt attgagcaca aagtttgtca tattatcaaa aaactttata
    79621 aataaattaa agaggaagga ggcataagta tgaatcaagc gcattattat ctcataggaa
    79681 actttaagat tagtgaaaca atactagtaa gttggggaat aatggccttt ttagcgatag
    79741 catcttattt tttgactaga aacttaaaaa aagttccaac tagtaaagtt caaatattct
    79801 tagaatttgc agtaggtggt cttgctaaaa tggttacaga tgttatgggt aaaaatacag
    79861 taaaaagaat gccatatatg ataccataca taggaagctt gtttttattt ttcgcatgtt
    79921 caaatttaag cccattactt ggattaaggt caccaacaac cgacttagac acaactgctg
    79981 catgggcaat gattacattt tttatgattt attttgcagg agttaaattt aaggggttat
    80041 catactttaa agaattggct caaccacttg ccataatgtt accaatcaat attataggtg
    80101 agttagctag accaatatca ttaagtttcc gtccatttgg gaatatttta ggtggaacaa
    80161 taataatggg tctgttttat caacttttag gttttatatc tagtttaata ccaggattat
    80221 caataccaat tggagaaata ttaataccag tcccattaca cttgtacttt gacttatttg
    80281 caggattgtt acaagcatat atatttataa tgttaacaat ggtatttata tcaagtgcag
    80341 gagagttaga ttaagaaatc aacttatatt aagataaaaa taaaataatt taaaaaatta
    80401 aagttttaag gaggaaataa ttatggaaac agcaatagta gcggcagcat cagcaatagg
    80461 agcagggata gcagttgcaa caggtatagg tgcaggtata ggtcaaggta tagcagcagc
    80521 taaagctgca gaagcagtag gaaaccagcc agaagctaaa ggtgatataa catcaacttt
    80581 attactagga gttgctatag cagagtcttc agcaatatat ggtttggtta tatcaataat
    80641 acttctattc gtaaatccat tctttaaata cttaggaatg tagatttagt ccttaaatat
    80701 tttgagatag gtttataggt aaatcatctc aaacttataa tcatgagatg aactttatca
    80761 tctcgtgatt ataagtagtt atgatttatg gaaaggagga taattatgga aaaagcacta
    80821 gtaggtataa cgtgggaatt tgtgttccaa attgttaata cttttataat atttttactt
    80881 ctgagaaagc ttttattcaa gccagtatta aatataattg aatcaagaga aaatgatatt
    80941 aaaagtgatt tggcagaagg cgaaaaagca aaaaatgaag gtttagctct gaaaaaagaa
    81001 tatgagtcaa aaatcaattt tgccaaagat gaaggtcaag aaatcataaa acaagcaact
    81061 ataagagcag agcagaaatc agatgatata gtaaatactg caaagaaaga tgctcttgat
    81121 ataaaagaaa aagcaaacaa agatatagaa caagaaagac aaaaggttat aaatgaaatc
    81181 aaaaatgata tatctaacat agcactactt gcagcatcta aagttattga aaaagattta
    81241 gataaatcta aacatgaaga attgatagaa aactttataa aagaggtagg ggaagctaaa
    81301 tgataaatgt aatagcaaat agatatgccg aagccctatt tcaattagga gaagaagaaa
    81361 attcaactga tgtcttattc aaagaactag aaaaagtagt agatatgatg actaaagtta
    81421 gtaaagattt ctacaaagtt ttaaaatcac cattagtttc aaaatcagaa aagaaaaact
    81481 tggtagaaat tatttttagt aaagaagtaa gttctaacat aaaaaacttt ttaaaagttt
    81541 tagtagataa agatagaata tcatatttag aagatatcga attagcttat aaagaattat
    81601 taaataagaa aaacaatgta attgatggag tagcaataag tgctattcca atgagtgaaa
    81661 cagatattaa agaacttgaa gtcaaacttt caaataaata caacaaaaat gttactatag
    81721 aaaatgttgt tgacaagact atactagggg gagttctagt tagaattgga aatgaacaaa
    81781 tagatggcac tgtgaaaact cgtcttgata agatgaaaga aaagctatct gaagtaatat
    81841 cttaagaatg gcggtgaacc catgaactta aaacctgaag aaataagttc tataattaaa
    81901 cagcaaataa aaaattatga gaataaagtt gagttgacag atacaggtag tgttttaaca
    81961 gttggggatg gtatagcgag tgtatatgga ttagaaaaag ctatgtctgg tgagttgcta
    82021 gagttcccag gtgaaatata tggtatggca cttaacttgg aagaagaagt agttggagct
    82081 gttatccttg gagatgacag tgaaataaaa gaaggcgata tagttaagag aactggaaga
    82141 atagttgaag ttccagttgg agaagcttta ataggtagag ttgtaaactc actaggtcag
    82201 ccaatagatg gaaaaggacc tatagcgtac acaaaaacta gaccagttga atctgaggca
    82261 cctggtataa tagatagaag gtctgtttat gaaccattac aaacaggaat caaatcaata
    82321 gattcaatga taccaattgg tagaggtcaa agagagttaa taataggtga cagacaaact
    82381 ggtaaaacat ctatagttat tgacactata ctaaatcaaa aaggaaaaga tgttatctgt
    82441 atatatgtag caattggaca aaaacgttct actatagctc aattagttag ctctttagaa
    82501 aaaggtggag ctttggatta tacaatagta gtttcagcaa cagcatctga atcagcacca
    82561 cttcaatata tagcaccata tgctggagca gctatgggtg aagaatttat gtacaatggg
    82621 aaacatgtac ttatagtgta tgatgattta agtaaacaag ctgttgcata tagagaaatg
    82681 tcattgttac ttagaagacc accaggacgt gaggcatatc ctggagatgt attctattta
    82741 cattcaagat tacttgaaag agcagctaag ttatctgatg aattgggtgg aggttcaatg
    82801 actgccttgc ctataataga aactcaagct ggtgacgttt ctgcatatat accaacaaat
    82861 gttatatcta taacagatgg tcaaatatac ttacaaccag agttattcta ttcaggtgta
    82921 agaccagcag ttgaccctgg tatatcagta tcaagggttg gtggttctgc gcaaattaaa
    82981 gcaatgaaaa aagttgcagg aacattaaaa cttgcatatt cacaatatag agaacttgca
    83041 gcattctcac aatttggttc tgacttagat gaagatacta aaaagagact tgctcaaggt
    83101 gaaagaatcg ttgagatatt aaaacaaggt gagcatcaac caataaaagt tgaaaatcaa
    83161 gttatgataa tatatgctgt tataaataat catttagagg atattccgat agataatata
    83221 gctagatttg aatcagaatt gtatgcattt gtagataata attatccgga aatatcaaga
    83281 aaaatattag gtggagaaga cttcactcat gatttaacag atgcaataaa tgaatttaaa
    83341 gaaaagtttg ttgttgaagt ataatccttt ttaaaaaagg aggtaaatta attggcagga
    83401 gctggaatca aagcaatcaa aacacgtatg ggaactgttg aaagtacaaa gcaaataact
    83461 aaagcaatgg aattagttgc atcttctaag cttagaaaag caaaagaaaa ggctgaagat
    83521 tcaagagaat attttaatac tttatacaat acagtaaaag atattgccca aacaacacgt
    83581 ggaattagaa atgaattttt aaaagaaaga gaagtaaaaa ataaatgcta tgtagtagta
    83641 gctggagaca gaggacttgc aggtggatac aattctaatg tattaaagga atctgtctct
    83701 catatgaaag gtaaaaagga aacagtgatt actgttggaa agaaagcaca tgaatttttt
    83761 tctaaaagaa actacaatat agcaaaagat ataaatagtg ttgaagcttg tggatatgaa
    83821 gatgcgacag aaatttcaca aactattatt gacctgtata aaaaaggtga agtagatgaa
    83881 gtttatattg cttatacaaa atttaaatct gctttatcac aagaagttga aattttgaaa
    83941 ttgcttccat tagtctttga aaaagataca gacgaacaag gaatggcagt aaaagaagaa
    84001 aaacaaaata gatcaaaagt acaatatata ccatcagcag aagcagtttt aagttatatt
    84061 gtacctcagt ttatatcagg tacagtatat ggtggaattt tggaatcttt tgcatcagag
    84121 caaggtgcta gaagaactgc aatggaatca gccacagaca atgcgaatga aatgctatct
    84181 aatttagagt taagttataa cagagcaaga cagtcagctg taactcaaga aataacagag
    84241 atagttggtg gagttgaagc tctaaaatag ggaggttagg aaatggcaaa tgtaggtaaa
    84301 gtagtacaga ttgtaggagc tgtactagat gttaagtttg atagtgaaca aagcctacct
    84361 aacttattaa atgcgttagt aataaagtta ggagataaag aaatagttgc agaagttgct
    84421 caacatatag gtgatgatac tgtaagatgt atagctatga gtgcaacaga cggacttgta
    84481 agaggtatgg aagttgtaga tacaggaggg ccaataagtg ttcctgttgg agatgaaact
    84541 ttaggtagaa tattcaatgt tcttggaaaa ccagttgatg ggaaaccagc tccaaaatct
    84601 gcacctaaat tacctataca tagaccagca ccggcgtatg atgaactaga aactacagca
    84661 gagatactag aaactggtat taaggtagtt gacttactag ctccatatct aaaaggtgga
    84721 aaaataggtc tatttggagg agcaggagta ggaaagacag ttctaataca agagcttata
    84781 aacaatattg ctaagcaaca tggtggtatt tctgtatttt caggagtagg agaaagaaca
    84841 agagaaggta acgaccttta tggcgaaatg agtgagtctg gagttataaa taaaacagct
    84901 ctagtatttg gtcaaatgaa tgaaccacct ggagcgagaa tgagagttgc tttaactgga
    84961 cttacaatgg cagaacattt tagagatgag caaggacaag acgttttact tttcgttgat
    85021 aatatattcc gtttcacaca agctggttca gaagtttcag cacttctagg acgtatgcca
    85081 tcagctgttg gttatcagcc aacattagct actgaaatgg gtgcacttca agagagaata
    85141 acatcaacta agaaaggttc aataacatct gttcaagcag tatatgtacc agcagatgac
    85201 ttaactgacc cagcaccagc tacaacattc tctcacttag atgcaaaaac agttttatca
    85261 agacaaatat catcactggg tatatatcca gcagttgacc ctcttgaatc tacatcaagg
    85321 attcttgacc ctagtatagt aggaaaagaa cattatgaag tagccagagg tgtacaatca
    85381 atacttcaaa gatataaaga acttcaagat ataattgcta tacttggtat ggatgaatta
    85441 tctgatgaag ataagttaat agttgcacgt gctagaaaga tacaaagatt cttatctcaa
    85501 tcattcacag ttgctgagca atttacagga aatccaggtc aatatgttcc tgttaaagag
    85561 actgtaagag gatttaaaga aattcttgaa gggaaacatg atgacttacc agagtcagca
    85621 ttcttatttg taggaacaat agaagacgct gttagaaaag cgaagggaag tatgtagtca
    85681 tggccagtga attttcattg aaagttgtaa ctccaagtaa tactttttat gatggagatg
    85741 ttgaaatgat agtagttaga actacaaaag gagacaaagg ggtgttgaaa ggtcatatac
    85801 catttgtttc aggtatacct gtaggaactt taaagataaa aaaagaggga agttttaaag
    85861 aggcgaaaat agcagaagga ttcattaatg taactcaaga taaaactgtc atattgacag
    85921 aatctgctga gtggatttaa taaattaatt tagagtataa aaagtcattt tgaccaaaaa
    85981 aacttttggg taaaatggct tttttgcgtt ttggtgttaa taaaataacg ataaaattgt
    86041 aagtttttag tgataataaa ttcacaaaat gtttaaattt actgccaaat tatgttgtaa
    86101 ttaataagat aaagaagatt tagatagctt ttatgtaagt gaaaaagtct tcatataaga
    86161 aatacatata aaatttttat aaaatttaaa aaatttgctt agttgtgtag tataataaat
    86221 aatataatag atttgtatat aatattcatt acaaataatt ttaaaagtta cagttttatt
    86281 ataatgatta ttaaattaag ataagtaaca taaactaaat aataatgtgt attatcgata
    86341 gtaaatttat aaattcatta ttaattattg aaagaagtat tataaatttt ctggaggaac
    86401 aatgaatata tttgatattg gcgtagatat aattgaaatt gatagaataa gaaaggctgt
    86461 agacaaaaat aataggtttt tggagaagat atttacagat agagaaatag agtattttaa
    86521 ttctaagaat tttaaagcag aaagtatagc aggtaatttc gcagccaagg aagctataag
    86581 taaatctata ggtacaggaa ttagagtgtt taattttaaa gatatagaag ttctcagaaa
    86641 tgaaatggga aaaccaatag taaaaactta taataatcta gcaaaaatgt gcatagatta
    86701 taatgtttta gaaataaaag tttcaatatc acattcaaaa gattatgcta tagcaaatgc
    86761 gataaccata attaaggact aaggagtgat tacattatga tggataaaac agcaaaagaa
    86821 ataatgacaa cagatgtaat agtagcaaaa caagatgata gtatagcaga tgtagctaat
    86881 atgctaattg cagaaaaaat aggaggtctg ccagttgtag attcagagaa tagagttgtt
    86941 ggaataattt ctgaaacaga tattcttaaa aaagaaaaat atatagaagc acctctctat
    87001 ataaatctat tacaaggatt gattttctta gatgacttaa aaaaagttga aaaagatata
    87061 aaacaagtag ctgcttataa ggttggagaa cttatgtcta aagatataat aaaggttcat
    87121 gaagatgata agtttgatga tgtagctaat gtaatgatta aaaaatcaat aaacagagtt
    87181 cctgtagtag atgatgacaa caaacttaaa ggtataattt gtagatatga tataataaaa
    87241 gctttataca atgaataaac tgaagtagga ggtgtgatgt gagaaaaaag tggaccatag
    87301 tatgtattat gttcttggca ctggttataa ttgtaatagg atgccaaaaa cgacagtcca
    87361 caaaagaaga agtatacaaa gattttcaaa agcagatttc tgatatgaat tattacagtt
    87421 gtaaagctga agtagaagta gttggaaata aaagcccaca caattatgtt ttaattcata
    87481 cttataaaaa aaccgataac tataaattag aagtaatttc cccaaaacat ttaaaaggga
    87541 aaagtataga atatcaaggt gataaaatat tagttaaaaa tccaaagatt agtgatgtag
    87601 tggagttacc taatacagga aaaaataatc aatatctttt tgtaggagac tttataaaaa
    87661 attatcttca aaatgaggag atgaaagtaa agttatccaa aggacatttg gttttagaga
    87721 cttttattcc tggggataat aaatatttta acaagcaagt attatatgta aatgctgaca
    87781 caaaaaatcc tgaaaaaatg gaagtgttag ataaagaggg agtgccaaga tttacagtaa
    87841 aatacaaaga ttttgaatac agaaactaag ggggactaaa gacatgcaaa aaataacagt
    87901 gcctacatgg gcagagataa atctagataa cttaagattt aacttaaata atattaaaaa
    87961 tttattagaa gaagatatta agatttgtgg agtaataaaa gctgatgcat atggacatgg
    88021 tgcagtagaa gttgcaaaat tgctagaaaa agaaaaagta gattacttag cagtagcaag
    88081 aactgctgaa ggaattgaac ttagacaaaa tggcataaca cttcctattt tgaacttggg
    88141 atatactcca gacgaagctt ttgaagattc tataaaaaat aaaataacta tgacagttta
    88201 ttctttagaa acagcacaaa agataaatga aattgcaaaa tctttaggag aaaaagcctg
    88261 tgttcatgtt aaaatagact cagggatgac tagaataggt ttccaaccta atgaggagtc
    88321 agtacaggaa ataatagaat taaataaatt agaatatata gatttagaag gtatgtttac
    88381 tcattttgct acagctgatg aagtaagtaa agagtacact tataaacaag ctaataatta
    88441 taaatttatg tctgataaat tagatgaggc tggtgtaaaa atagctataa aacatgtatc
    88501 aaacagtgca gctattatgg attgccctga tttaagatta aatatggtaa gagcaggaat
    88561 aatattatat ggtcattatc catctgatga tgtatttaaa gatagattag aattaagacc
    88621 agccatgaaa ttaaaatcaa aaatcggaca tataaaacaa gttgaaccag gtgtaggaat
    88681 aagttatgga ctaaaataca caactacagg taaagaaaca atagctacag ttccaatagg
    88741 atacgcagat ggatttacta gaatccaaaa aaatccaaag gttcttatta agggagaagt
    88801 gtttgatgta gttggtagaa tatgtatgga tcaaataatg gttagaattg acaaagatat
    88861 agacataaaa gttggagatg aggttatact atttggagaa ggcgaagtta cagctgagcg
    88921 tatagctaaa gacttaggaa ctataaacta tgaagtgtta tgtatgatat caagaagagt
    88981 tgaccgtgtt tatatggaaa ataatgagct tgtacaaata aacagttatt tgctaaaata
    89041 aaaccatgat attataatct gggaggcgat tttgtgtacg ataagagtaa agaaaaaata
    89101 gaagttactt tacctgactc tctgatttct gaagttgata gtatagttca gatggagaac
    89161 agtaacagag aagattttgc aaaagctgct tttcagttct atataactca gaaaaagaaa
    89221 attcatatta aagaatctat gaaaacgggt tatagagaaa tgggtcaaat taatctgtca
    89281 ctagctgaat taggtatgac agttgaagaa gtatcttctg atgataaaaa tgaagggaag
    89341 attgcccaag gtgagtacta attgtgaaat aaagcgtggt gatttatatt acgctgattt
    89401 aagtccagtt gttggttcag agcagggagg cgttagacct gttctgataa tacaaaatga
    89461 tgtaggtaat aaatatagtc ctacagttat agtatcagct ataacatctc agattaataa
    89521 agccaaatta cctactcatg tagagataag ttccaatgaa tatgggctta ataaagactc
    89581 agtaattctt ttagagcaaa ttagaactat cgataaaaag agactgaggg aaaaaattgg
    89641 ttgtctagat gaaaatatga tgataaaagt agatgatgga cttcaaataa gtttaggatt
    89701 gtttactttt taaagaggga tttgtctttt attagacaat cccttttttc ttttaaatat
    89761 ctcttaaggt ttaattttaa tgtactatgt taataaaatt aaaaataacg caaaaaaata
    89821 gcataaaagt gatataataa tatggaattg atataaaatt acgaactcaa gggaggtaat
    89881 tgcatgagag accataaagg attaaatgag attgcgcgta tcataagaag agatatagtt
    89941 tcaatgatac atagagccaa atctggacat ccaggagggt cattatcagt agttgaaata
    90001 cttactgcgt tatactttga tgaaatgaat gtggattctt caaatcctaa aatggaggat
    90061 agagatagat ttgtattatc aaaaggacat gctgcaccag cattatatgc tacattggct
    90121 gaaaaaggct attttgataa ggaagaaatg aatggattaa ggaagatagg aaggatgtta
    90181 caaggtcatc cagacatgaa aggcacgcca ggtgtggaaa tatctactgg ttctttaggt
    90241 caaggttttt cagttgcatg tggtatggct atggcatcaa agttggataa tgctccgtgg
    90301 aatgtgtata ctttgcttgg tgatggtgag gttcaagaag gaattgtttg ggaagctgct
    90361 atgagtgctg cacattataa acttgataat ttaattgctt ttttagataa taatggactt
    90421 caaatagatg gagatataga aagcgtaatg agtttaggtt caatagttga taaatttaaa
    90481 gcttttggtt ggaatgtaat tgagatagat ggacatgatt ttgaccaaat atttgcggct
    90541 cttgatatag ctaaatcaac agttaaaaaa cctacaatga tagttgcaaa aactataaaa
    90601 ggcaaaggaa tatcttttat ggaaaatcaa gcaggatggc atgggacagc tccaagtgat
    90661 gaggagctag aaaaagcctt gcttgaatta ggaggtgttg acaatgagta aaatggcgac
    90721 gagagaagca tatggtaagg cattagtaaa attaggtcaa ataaatgaca atgttgtagt
    90781 attagatgca gatttatcaa agtctacaaa aacacatgat ttttacaaga catttccaga
    90841 tagatttttt aatatgggta tagctgaaca aaatttaata ggcgctgctt gtggattatc
    90901 aactgctggt aaaatacctt ttgcaagtac tttcgctatg tttgctacgg gaagggcctt
    90961 tgagattata agaaattcag tttgttatcc aaagctaaat gtaaaaatat gtgctactca
    91021 tgcaggtctt actgttggag aggatggagc atctcatgaa agtgtagaag atattgctat
    91081 aatgagagct ataccaaata tgacagttct tgttccagct gatggagttg aaacagaaaa
    91141 aattattttt gaaatagcta agtataatgg acctgtttat gttagattag ggagaagttc
    91201 agtaccagtt ttatttgatg aagattataa atttgaaata ggaaaaggta cagtcttaag
    91261 agaaggaaag gatgtatcaa ttatagcttg tggaattatg gtaaatgaag ctctattagc
    91321 acaagaaaag ttgcaagaag aaggtataag tgctagagtt ataaacatgt cctcgataaa
    91381 acctatagac aaagatttaa tattagaatc agcaaaagaa acgaatgcta ttgtaactgt
    91441 agaagaacat agcataattg gtggattagg ttctgctgta agtgaggtag tgggagagtc
    91501 ttgtccaacc attgtaaaga aagttggaat taaagataca tttggagaat ctggtacccc
    91561 aaatgaattg ttaaaaaaat atgaattaac ttgtgatgac atagtaaaga ctgttaaaga
    91621 agctattatt gcaaaaagaa tgtaagagat ataaattatt catgtttgtt aataatataa
    91681 tatatttaaa agagaggtat aaagtgttat attaatttat atctctcttt tttttatatg
    91741 atatcaatat atcaaaaata taataaaata ttcaaatttt tacaaaaata gagaaaata
//
LOCUS       DAEPUT010000005        90218 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.005, whole genome shotgun sequence.
ACCESSION   DAEPUT010000005 DAEPUT010000000
VERSION     DAEPUT010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 90218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90218
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.005"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            118..2529
                     /locus_tag="KRL22_000460"
     CDS             118..2529
                     /locus_tag="KRL22_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HBH1270984.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMDLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            2826..4403
                     /locus_tag="KRL22_000461"
     CDS             2826..4403
                     /locus_tag="KRL22_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HBH1270985.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSPNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGAAVLNKDIENKLKSNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNEDQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
     gene            4537..5850
                     /locus_tag="KRL22_000462"
     CDS             4537..5850
                     /locus_tag="KRL22_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HBH1270986.1"
                     /translation="MGIGIECNKKINKSIDKTRIKKNNLNSNSNSNSNSNSNSNSNSN
                     SNSNSNSNSNSNKISNNAVDSKLMNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQL
                     RHAVWHGVTLADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILFG
                     FFLNYLGNPDLDTVRILGVLQRMGLVYFVTSLVYLLLKKLNVGSTATIITFLCISTFI
                     IVGYYILAKPYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTM
                     GCVLLKENLGEYKKFFKILVMSIILLICAFIFNQYFPFNKRLWSSSFVLLMAGSYGIL
                     LSIFYFICDIKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLV
                     EWTTYELITPWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            6104..8128
                     /locus_tag="KRL22_000463"
     CDS             6104..8128
                     /locus_tag="KRL22_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1270987.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            8348..9034
                     /locus_tag="KRL22_000464"
     CDS             8348..9034
                     /locus_tag="KRL22_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBH1270988.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            9129..10184
                     /locus_tag="KRL22_000465"
     CDS             9129..10184
                     /locus_tag="KRL22_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HBH1270989.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            10299..11855
                     /gene="murJ"
                     /locus_tag="KRL22_000466"
     CDS             10299..11855
                     /gene="murJ"
                     /locus_tag="KRL22_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH1270990.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            11901..13607
                     /locus_tag="KRL22_000467"
     CDS             11901..13607
                     /locus_tag="KRL22_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH1270991.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFKEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            13629..14702
                     /locus_tag="KRL22_000468"
     CDS             13629..14702
                     /locus_tag="KRL22_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HBH1270992.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            14714..15436
                     /locus_tag="KRL22_000469"
     CDS             14714..15436
                     /locus_tag="KRL22_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1270993.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            15452..16609
                     /locus_tag="KRL22_000470"
     CDS             15452..16609
                     /locus_tag="KRL22_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HBH1270994.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            16612..17451
                     /locus_tag="KRL22_000471"
     CDS             16612..17451
                     /locus_tag="KRL22_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1270995.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            17466..18641
                     /locus_tag="KRL22_000472"
     CDS             17466..18641
                     /locus_tag="KRL22_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBH1270996.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            18670..19419
                     /locus_tag="KRL22_000473"
     CDS             18670..19419
                     /locus_tag="KRL22_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1270997.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            19441..20349
                     /locus_tag="KRL22_000474"
     CDS             19441..20349
                     /locus_tag="KRL22_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1270998.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            20397..21149
                     /locus_tag="KRL22_000475"
     CDS             20397..21149
                     /locus_tag="KRL22_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1270999.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            21127..22470
                     /locus_tag="KRL22_000476"
     CDS             21127..22470
                     /locus_tag="KRL22_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HBH1271000.1"
                     /translation="MPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLAEVGNENVV
                     CVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDVDVILIAVG
                     TPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYINRNLKNDVK
                     VELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPIIVTNRNSAE
                     MIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLKAGIGYGGS
                     CFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQDMKVAVLGL
                     TFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYADSVDDAIE
                     DAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEDLGIEYYSIGR"
     gene            22476..23567
                     /locus_tag="KRL22_000477"
     CDS             22476..23567
                     /locus_tag="KRL22_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1271001.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKKAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            23651..25564
                     /locus_tag="KRL22_000478"
     CDS             23651..25564
                     /locus_tag="KRL22_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH1271002.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFMATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKDIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIADLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            25763..26470
                     /locus_tag="KRL22_000479"
     CDS             25763..26470
                     /locus_tag="KRL22_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH1271003.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYAKRLITATRVLQ"
     gene            26772..28883
                     /locus_tag="KRL22_000480"
     CDS             26772..28883
                     /locus_tag="KRL22_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HBH1271004.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDNWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(29081..30046)
                     /locus_tag="KRL22_000481"
     CDS             complement(29081..30046)
                     /locus_tag="KRL22_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH1271005.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(30331..31287)
                     /locus_tag="KRL22_000482"
     CDS             complement(30331..31287)
                     /locus_tag="KRL22_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH1271006.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            31655..32443
                     /locus_tag="KRL22_000483"
     CDS             31655..32443
                     /locus_tag="KRL22_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1271007.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(32566..33036)
                     /locus_tag="KRL22_000484"
     CDS             complement(32566..33036)
                     /locus_tag="KRL22_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HBH1271008.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            33175..33819
                     /gene="uppS"
                     /locus_tag="KRL22_000485"
     CDS             33175..33819
                     /gene="uppS"
                     /locus_tag="KRL22_000485"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HBH1271009.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            33862..34767
                     /locus_tag="KRL22_000486"
     CDS             33862..34767
                     /locus_tag="KRL22_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1271010.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHPNRKKRKLNKKKLAMLICFTVLFLFIAFKATQGVVALVKSMDKSNKTSQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQAVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            35082..36629
                     /locus_tag="KRL22_000487"
     CDS             35082..36629
                     /locus_tag="KRL22_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1271011.1"
                     /translation="MNKNSMTKIYSLNKIIFIIIGILGIVLLTRHIGVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKVIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMKISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            36632..37030
                     /locus_tag="KRL22_000488"
     CDS             36632..37030
                     /locus_tag="KRL22_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH1271012.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            37070..38803
                     /locus_tag="KRL22_000489"
     CDS             37070..38803
                     /locus_tag="KRL22_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBH1271013.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKTNLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            39035..40246
                     /locus_tag="KRL22_000490"
     CDS             39035..40246
                     /locus_tag="KRL22_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH1271014.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIVQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            40439..40699
                     /locus_tag="KRL22_000491"
     CDS             40439..40699
                     /locus_tag="KRL22_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBH1271015.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            41052..42764
                     /gene="ptsP"
                     /locus_tag="KRL22_000492"
     CDS             41052..42764
                     /gene="ptsP"
                     /locus_tag="KRL22_000492"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBH1271016.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            43087..44637
                     /locus_tag="KRL22_000493"
     CDS             43087..44637
                     /locus_tag="KRL22_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1271017.1"
                     /translation="MRYKKRNIDKSSELSFQSLAKYFITFYIVIILIILSMFCINTIW
                     VMKKDNQDLLSTTSNRIEDRVGETIKLLNSLSKDNYIIDNSVNGIDKSKELSMYSDEF
                     GYMMICFVDKNIIVWDEEGGNISLAGRDYMQKLFATKKYQVTDSFAAGADGKTLNYTI
                     ASPIIKNGNVDGCVFAAIYFDEIKDILKQGKGQQQQNFILFGSENQIMNLTSDETAYG
                     EKYMKLSQKTKYLGTNAKKVEKDMFNNKSGDYWAFENGKLYFMSYKPIKNTNWSLFCK
                     VNFLDIFALNLIPMGAILSVITLVFIILICMEKSFMKKRMEVIDMLLGSVQELEKRIY
                     QTERPSEVDFKEIIQLTSKGLTDGLTGVVTRTVFFDQIYNRVEMEENDKLSVISFVDL
                     DDLKCINDLYGHEIGDMVLKNVGYVLREYEIKYNGLIGRYGGNEFVMLLSGFTSREEV
                     EDLLDEIAIRLHTEVLTDDGIIQTHCSVGAVVCSVKDNKDIDNLLKQADEALYYVKRN
                     GKGNYHLV"
     gene            44663..47364
                     /locus_tag="KRL22_000494"
                     /pseudo
     CDS             44663..47364
                     /locus_tag="KRL22_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728915.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(47870..48535)
                     /locus_tag="KRL22_000495"
     CDS             complement(47870..48535)
                     /locus_tag="KRL22_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271018.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            48879..50309
                     /locus_tag="KRL22_000496"
     CDS             48879..50309
                     /locus_tag="KRL22_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH1271019.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSCVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            50676..51254
                     /locus_tag="KRL22_000497"
     CDS             50676..51254
                     /locus_tag="KRL22_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBH1271020.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            51284..51430
                     /locus_tag="KRL22_000498"
     CDS             51284..51430
                     /locus_tag="KRL22_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBH1271021.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            51735..53114
                     /gene="scfB"
                     /locus_tag="KRL22_000499"
     CDS             51735..53114
                     /gene="scfB"
                     /locus_tag="KRL22_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HBH1271022.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            53143..53640
                     /locus_tag="KRL22_000500"
     CDS             53143..53640
                     /locus_tag="KRL22_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBH1271023.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            53938..55602
                     /locus_tag="KRL22_000501"
     CDS             53938..55602
                     /locus_tag="KRL22_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBH1271024.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            55615..58065
                     /gene="recJ"
                     /locus_tag="KRL22_000502"
     CDS             55615..58065
                     /gene="recJ"
                     /locus_tag="KRL22_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBH1271025.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            58078..58590
                     /locus_tag="KRL22_000503"
     CDS             58078..58590
                     /locus_tag="KRL22_000503"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBH1271026.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            58664..60871
                     /locus_tag="KRL22_000504"
     CDS             58664..60871
                     /locus_tag="KRL22_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBH1271027.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            60896..61345
                     /locus_tag="KRL22_000505"
     CDS             60896..61345
                     /locus_tag="KRL22_000505"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBH1271028.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            61360..61974
                     /locus_tag="KRL22_000506"
     CDS             61360..61974
                     /locus_tag="KRL22_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1271029.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            62065..63621
                     /locus_tag="KRL22_000507"
     CDS             62065..63621
                     /locus_tag="KRL22_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HBH1271030.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFVVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKETKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            63611..64873
                     /locus_tag="KRL22_000508"
     CDS             63611..64873
                     /locus_tag="KRL22_000508"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBH1271031.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            64947..66734
                     /gene="aspS"
                     /locus_tag="KRL22_000509"
     CDS             64947..66734
                     /gene="aspS"
                     /locus_tag="KRL22_000509"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBH1271032.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            67193..68425
                     /locus_tag="KRL22_000510"
     CDS             67193..68425
                     /locus_tag="KRL22_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH1271033.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            68439..69245
                     /locus_tag="KRL22_000511"
     CDS             68439..69245
                     /locus_tag="KRL22_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HBH1271034.1"
                     /translation="MGRKVKIGIIQQHSVLGNVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(69357..70226)
                     /locus_tag="KRL22_000512"
     CDS             complement(69357..70226)
                     /locus_tag="KRL22_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1271035.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            70598..72025
                     /locus_tag="KRL22_000513"
     CDS             70598..72025
                     /locus_tag="KRL22_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HBH1271036.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNDLNSQTEKELK
                     RLGVKKVYIIGLSSSISNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(72102..72371)
                     /locus_tag="KRL22_000514"
     CDS             complement(72102..72371)
                     /locus_tag="KRL22_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271037.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(72374..73816)
                     /gene="nhaC"
                     /locus_tag="KRL22_000515"
     CDS             complement(72374..73816)
                     /gene="nhaC"
                     /locus_tag="KRL22_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH1271038.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(73841..75007)
                     /locus_tag="KRL22_000516"
     CDS             complement(73841..75007)
                     /locus_tag="KRL22_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1271039.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGDYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(75232..77352)
                     /locus_tag="KRL22_000517"
     CDS             complement(75232..77352)
                     /locus_tag="KRL22_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1271040.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIAAKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            77580..77981
                     /locus_tag="KRL22_000518"
     CDS             77580..77981
                     /locus_tag="KRL22_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271041.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            78024..78317
                     /locus_tag="KRL22_000519"
     CDS             78024..78317
                     /locus_tag="KRL22_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBH1271042.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            78332..78772
                     /locus_tag="KRL22_000520"
     CDS             78332..78772
                     /locus_tag="KRL22_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HBH1271043.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(78864..79337)
                     /locus_tag="KRL22_000521"
     CDS             complement(78864..79337)
                     /locus_tag="KRL22_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1271044.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYKKSK"
     gene            complement(79337..80125)
                     /locus_tag="KRL22_000522"
     CDS             complement(79337..80125)
                     /locus_tag="KRL22_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1271045.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            80453..81697
                     /locus_tag="KRL22_000523"
     CDS             80453..81697
                     /locus_tag="KRL22_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH1271046.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            82020..83117
                     /locus_tag="KRL22_000524"
     CDS             82020..83117
                     /locus_tag="KRL22_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH1271047.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            83108..83806
                     /locus_tag="KRL22_000525"
     CDS             83108..83806
                     /locus_tag="KRL22_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1271048.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKKVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            83809..84873
                     /locus_tag="KRL22_000526"
     CDS             83809..84873
                     /locus_tag="KRL22_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH1271049.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            85056..85760
                     /locus_tag="KRL22_000527"
     CDS             85056..85760
                     /locus_tag="KRL22_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271050.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            85753..87075
                     /locus_tag="KRL22_000528"
     CDS             85753..87075
                     /locus_tag="KRL22_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1271051.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            87262..88635
                     /locus_tag="KRL22_000529"
     CDS             87262..88635
                     /locus_tag="KRL22_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HBH1271052.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(89007..89945)
                     /gene="pdaA"
                     /locus_tag="KRL22_000530"
     CDS             complement(89007..89945)
                     /gene="pdaA"
                     /locus_tag="KRL22_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH1271053.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        35412 a         9833 c        15620 g        29353 t
ORIGIN      
        1 aaactataat attctataat taatatgtac tcataatcca tattttatca aaataaaata
       61 tgaccttaat ttagaaatct gatataataa aaattaaata catataaggg ggtaaacatg
      121 agaaagtaca aatcaaaaaa attgtcaaag ctactagcat tgttgacagt ttgcttttta
      181 atagtgtcaa caatacctgt ctcagcagaa aaccataaaa ctctagatgg agtagaaact
      241 gcagagtatt ctgaaagcta tcttcaatac ctagaagatg tcaaaaatgg agacacagca
      301 aaatataatg gagtaatacc ttttccacat gaaatggaag gtacaacact tcgaaataag
      361 ggtagaagta gtcttccatc agcatataaa tcaagtgtag catacaaccc aatggatctt
      421 ggtcttacta caccagcaaa aaatcaagga agtcttaata catgctggtc tttttcaggt
      481 atgtcaacgt tagaagcata tcttaaatta aaaggatatg gaacgtatga cttatcagaa
      541 gaacatttaa gatggtgggc aactggtgga aaatatggat ggaacttaga tgatatgtca
      601 gggagttcaa atgtaacagc tataggatat ctgacagcat gggcaggtcc taagttagaa
      661 aaggacatac catataatct taaatctgag gcacaaggtg caactaaacc ttcaaatatg
      721 gatactgcac ctactcaatt taatgtaaca gatgttgttc gtcttaataa ggataaggaa
      781 actgtaaaga atgctataat gcaatatggt tcagtgacat caggttatgc acattattca
      841 acatatttta ataaagatga aacagcatat aactgtacaa ataagagagc tccattaaat
      901 cacgctgtag cgatagtagg atgggatgat aattattcaa aagataattt tgcatctgat
      961 gtaaaaccag aatcaaatgg agcatggtta gtaaaaagca gttggggaga gtttaattct
     1021 atgaaaggat tcttctggat ttcttatgaa gataaaactc tactaacaga tacagataac
     1081 tatgcaatga aatcagtatc aaaaccagat agtgataaaa aaatgtacca acttgaatat
     1141 gctggtctta gcaagataat gtcaaataaa gtaacagcag caaatgtatt tgattttagc
     1201 agagattctg aaaaacttga ctctgttatg tttgaaacag attctgtagg agcaaaatat
     1261 gaagtatatt atgcaccagt agtaaatgga gttcctcaaa acaattcaat gacaaaactt
     1321 gcaagtggaa cagtatcata ttctggatac ataaatgtac ctactaattc ttacagctta
     1381 ccaaaaggta aaggagcaat agtagtagtt atagacaaca cagcaaatcc taatagagaa
     1441 aaatcaactt tagcatatga aactgatata gatggatact atctatatga ggctaaagca
     1501 aacttaggtg aaagctacat acttcaaaat aataaatttg aagatataaa tacatatagt
     1561 gaattttctc cttgtaactt tgttataaaa gctataacaa aaacatcttc tggacaagct
     1621 acttcaggag aatctttaac tggagcagat agatatgaaa cagcagttaa agttagtcaa
     1681 aaaggatgga cttcttcaca aaatgcagta ttagtaaatg gagacgcaat agtggatgct
     1741 ttaacagcta caccatttac agcagcaatc gactctccaa ttcttttgac aggaaaagat
     1801 aacttagatt caaaaactaa ggcagagtta caaagattag gaactaaaaa agtttatcta
     1861 ataggtggag aaaattcttt aagcaagaat gtacaaactc aacttagtaa tatgggtata
     1921 tcagtagaaa gaatttcagg tagtgatagg tacaagacca gtatatctct agctcaaaag
     1981 ttaaatagta taaaatctgt ttcacaagtt gcagtggcaa atggtgtaaa tggacttgca
     2041 gatgcaataa gtgttggtgc agcagctgct gataacaata tgccaataat acttactaat
     2101 gaaaagagtg agttgcaagg tgctgatgag tttttaaatt catctaaaat aactaagtct
     2161 tatataattg gtggaacagc tactttatca tcaaatttag aaagtaagct ttcaaatcca
     2221 acaagacttg caggaagtaa tagaaatgaa actaatgcta agataataga taaattctat
     2281 cctagctcag atttgaaata tgcttttgtt gttaaagatg gttcaaagag tcaaggagac
     2341 ttgatagatg gactagcagt aggagcatta ggtgctaaaa ctgattcacc agtagtttta
     2401 gttggaaata agttagatga aagtcaaaaa aatgtactta agtctaagaa aatagaaact
     2461 cctattagag ttggtggaaa tggaaatgaa aatgctttta atgaactaaa tactctttta
     2521 ggaaaatagt gaatggaaag atagtaagga tatacatttt attattaaaa aatgttcaat
     2581 agaagtttat aaatataaaa taacaaaaag gggtgtctca aaatgaactt tttagttcat
     2641 gaggcactct tttttgttgt tttatatttt tatcatttaa ataatgaaaa ataggcttgt
     2701 ctatattttt acatagtttt cttattattg atgaaaaatg taataatttt aaactgtaaa
     2761 atagtgtaaa gttattttat aatataaata tagtaagatt ttaaacaaaa taagggggaa
     2821 taataatgaa agcaccaaaa actattttaa caatactgac aatagcgctt actttaagta
     2881 gcatttctat aataccatca tatgcactta cagaggaaaa attaataggt aatggtagat
     2941 atgaaactgc tgtaaagata agtcaaaagg catacagttc tagtcctaat gtagtgctag
     3001 ttaatgacaa ttcattagct gatgcacttt cagctacacc atttgcaaag gctaaaggag
     3061 caccaatact tttgacagaa agtgataagc tagatgatag gactgaaaaa gagataaaac
     3121 gtctaggagc taaagatatt tatttgatag gaggtgctgc tgtacttaat aaagatatag
     3181 agaacaagtt aaaaagtaat ggacttaatg tagaaagaat taatggtaag gatagatatg
     3241 aaacttcact gattttggct aataagctta aggatataaa agatattaag gaagttgctg
     3301 tagtaaatgg tgaaaaagga ttgagtgatg ctgttagtgt tggagcacca gcagctcaaa
     3361 ataagatgcc tataattttg tctagtccta aagatggcgt agaagcattt gataaattta
     3421 taagagatga gaaagttata aaagcatatg taattggagg tacaaattct gtttcaagag
     3481 ctgtagaaaa gagccttcct aatgcagaaa gagtgagtgg gaaagataga aatgagacta
     3541 atgctaaagt tatagaaaag ttttacactg atacaaattt aagtaattta tatgtaacta
     3601 aggatggtag taaaaatgag gatcaactaa tagactcgtt agctgttgga gtattggctg
     3661 caaaaaatga gtctcctgtt gttttggttg gtaataaatt aaacacaaaa caaagagata
     3721 tacttagtac taaaaaatta aatactataa cacaggtagg tggaaatgga aatgaagaag
     3781 cttttgatga aattaaaagt ctacaagaaa aaactgtgtt tgaagcaaaa actgttgagg
     3841 aattaactga tatgataaat atagcaagtc ctaatgatat tataaacttt aaaccaaaag
     3901 agaatactgt aaatgaagct tttagaatgg taacaaataa accaataact gtgaatataa
     3961 agggtgattg ttcaaagact cttacagtag atatgcctaa tggtgaagtg aataactatg
     4021 ctactttggt aaatgttata gttagaaata ttggagaagg tggatttaat aatcatgata
     4081 caatcactat attgtcagtt cgtgacaaaa atggtagagt tatagaaaat actagaaatt
     4141 cagatataga tacgttgatg atattagctt ctgctaatga tacaaaattg attaatgatg
     4201 gatatatagg aaaacttata gataattcat ctaatagtga tataactaat aatggtacta
     4261 tagataaaaa agttaatcag gttgaagatt tagaggctaa agtagattca attgaaaaag
     4321 ctatagattc tataagtcaa aaagtcaata aaatacaaga tatactagat aagcttggat
     4381 ttctaaagaa atttcttagc taagaatatg tatatttaag tgaagtgtgt gttgtaattg
     4441 ttctaaagtt atgtagttaa acaggtttat atacaaatag atttatagat aaatatgtag
     4501 tttagtatat atttgaataa gctttgggga ggtaacatgg ggattggaat tgaatgtaac
     4561 aaaaaaataa ataaaagtat tgacaaaact agaataaaga aaaataatct aaatagcaat
     4621 agcaatagca atagcaatag caatagcaat agcaatagca atagcaatag caatagcaat
     4681 agcaatagca atagcaatag caataaaatt tcaaataatg ctgtagattc taaacttatg
     4741 aatagtagga ttaaatcaat agatataata agagggctat caatagccct catgatagtc
     4801 tgtaataatc ctgggacttg gatgagaatg tatcctcaat taagacatgc tgtatggcat
     4861 ggtgtaacac ttgcagattt tgcatttcct ttttttgtta tatctttagg tgttacaatt
     4921 ccaatatcaa taaatagtaa actaaaaaat aataaatcca cactgagtat aatacttagt
     4981 atattcaaga gaagtatctt attgatattg tttggatttt tcttaaatta cctaggaaat
     5041 cctgatttag atactgtaag aatacttgga gtacttcaac gtatgggatt agtctatttt
     5101 gtgactagtt tagtatattt actactaaaa aaattaaatg ttggaagtac tgctacaata
     5161 attacttttc tatgtatatc tacatttata atagttgggt actacatctt agcaaaacct
     5221 tatggatttg agctagaagg ttctcttgca cagttagtgg atttacattt cttcaaggga
     5281 catttgtaca agccggaatt tgaaccagat ggttttttaa ctagtatagt agcaatttct
     5341 tcaggtatgt tgggatgcac tatgggatgt gtacttttaa aagaaaacct aggagaatat
     5401 aaaaaattct ttaaaatact ggttatgagc ataatcctgc taatatgtgc ttttatcttt
     5461 aatcagtatt ttccatttaa taaaagatta tggtctagct catttgtact tttaatggct
     5521 ggcagttatg gtatattact gtcaatattt tattttatat gcgacatcaa aaataaaagt
     5581 aaaatattta ccccaataat agcacttgga agtagcccta tttttacata tatgtgcctt
     5641 gaaatattga gtcatgtttt ttggaatgtt ccaaaactta cgaacaaagt cgattatcca
     5701 actaccttgg tagagtggac tacatatgaa cttataacac cttgggcagg tacaacttgg
     5761 gattctctta tattttcttt attgtatgtc ctattctggg ttatagtaat gtctataatg
     5821 tacaagaaaa aaatatttat taaaatttag tgcaatattt ttagatgata aagtctttga
     5881 tttgttcaaa tatacagaaa ctatcaaata taatcaaaat ttctcctcga taaaatttaa
     5941 aaaccatgcc ataaaagatt acaaaaagtt tgcaatttgt aattttttgt gctataatga
     6001 aaaaagattt acataatatt gaatttatgt aatataaaac aagcttaaga tgtattaaaa
     6061 aagatttaaa gatttaaaga accaaaaaat taggggggat atgatgaaaa aaacaacaaa
     6121 attattggca acaggaatgt tgtctgtagc aatggtggca ccaaatgtag ctttagcggc
     6181 tgaaaatact actgcaaata cagaatctaa ttcagatatt aatataaatt tacaaagaaa
     6241 aagtgtagtg ttaggaagta aatctaatgc aagtgtaaaa tttaaagaaa aattaaatgc
     6301 tgattcaata acattaaatt ttatgtgtta tgatatgcca cttgaagcta ctttaaatta
     6361 caatgaaaag acagattcat atgaaggtgt aataaactat aacaaagacc cagaatactt
     6421 aaatgtatgg gaacttcaaa gcataaaaat aaatggtaaa gatgaacaga aagttttaaa
     6481 caaagaagac ttagagtcta tgggattaaa tcttaaggat tatgatgtta cacaagagtt
     6541 tataataagt gatgcaaatt caacaaaagc agtaaatgaa tatatgagaa aaacttctgc
     6601 accagtaaaa aaacttgctg gagctactag atttgaaact gctgttgaga taagtaaaca
     6661 aggttggaaa gatgggtcta gtaaggttgt aatagttaat ggagaattag cagcagatgg
     6721 aattacagct actccacttg catctacata tgacgcacca atattacttg caaataaaga
     6781 tgatatacca gaaagtacaa aagcagagtt aaaacgtcta aatccaagtg atgtaataat
     6841 tataggtgat gatggttcag tttcacaaaa ggcagtgtct caaattaaat ctgctgtaaa
     6901 tgtaaatgtg actcgtattg gtggagttga tagacatgaa acatctttac ttatagcaaa
     6961 agaaatagat aagtatcatg atgttaataa aatatacata gcaaatggat atgctggtga
     7021 atatgatgct cttaatattt catcaaaagc tggtgaagac caacaaccta taatattagc
     7081 taataaagat tctgtaccac aaggtacata taattggtta tcttcacaag gtttagaaga
     7141 agcttattac ataggtggta gtcaaagttt atcatcaaaa attatagacc aaatatctaa
     7201 aatagcaaaa aatggtactt caaaaaatag agtttctgga gcagatagac atgaaacaaa
     7261 tgcaaatgta attaagactt tctatccaga taaagagttg agtgcaatgt tagttgcaaa
     7321 atctgacata atagttgatt caataacagc aggaccttta gcagctaaat taaaagctcc
     7381 aatacttata actccaaaaa cttatgtttc tgcataccat agtacaaact tatcagaaaa
     7441 aacagcagaa acagtatatc aaattggtga tggaatgaaa gatagtgtta taaattctat
     7501 agcatctagt ttatcaaaac acaatgcacc aacagaacca gataattcag gttcagcagc
     7561 aggaaaaact gtagtgatag acccaggtca tgggggttct gattcagggg caacaagtgg
     7621 attaaatggt ggagcacaag aaaagaaata tactcttaat acagcattag caactactga
     7681 atatttacgt tcaaaaggta taaatgttgt tatgactaga gatacagata aaacaatggc
     7741 tttaggagaa agaacagcat tatcaaatac tataaagcca gatttattta caagtataca
     7801 ttacaatgcg tctaatggag ctggtaatgg tgtggaaatt tattacaaag taaaagataa
     7861 aaatggtgga acaactaaga ctgcagcatc aaatatctta aaaagaatac tagaaaaatt
     7921 taacatgaaa aatagaggaa tcaagacaag aacacttgat aatggaaaag attacctata
     7981 tgtgttaaga aataataatt atccagcaat acttgttgaa tgtgcattta ttgacaataa
     8041 gagcgatatg gataagttaa atactgcaga aaaagtaaaa acaatgggaa ctcaaattgg
     8101 aataggaata gaagatacag taaaataaaa tagaaaatat taaagcaaaa catatcatct
     8161 cctgttataa tgtaaaatat aacaagagat gatatatttt tgtaaagaat caaattgttt
     8221 acaatgatgt ttcttgtatt gataatctgc tcattattga gtataatata gaaataagtc
     8281 aaaaataaga tagaaataag ttgaaattaa gaattaaaaa aatttttatt ccaatatgga
     8341 ggtaactatg tctggatata ctaatgatga gtgtgaaata cctaaaatta aaagctatcc
     8401 aggggcagat aaagaaattg caagtgagat tgactatagc atagtaaaag gaacagtttt
     8461 attcgacttg taccaaagaa ttatggattt agttttatct ataataggac ttgtgatagg
     8521 tttaccttta atagcaatat ttggaattct tattaaaata gaggacaaag gaccaataac
     8581 ttataagcaa gaaagactag gaaaatgcgg gagaagattc tatatatata aattgagatc
     8641 tatgagaaca gacgcagaaa aatttggcgc acaatgggct gaaaaagatg atcctagaat
     8701 aactaaggtt ggaaagttta ttaggaaaac tagaattgat gagattccac agctgtttaa
     8761 tatattaaag ggggacatgg gcttaatagg tcctagacca gagagaccga actttactgt
     8821 tcaatttaat gaggaaatac ctggatttat caacaggctc gctataaaac ctgggcttac
     8881 aggttgggca caagtaaatg gtggatacga aatcactcct gaagaaaaac ttaaagaaga
     8941 tatttactat ataaaaaata ggagtatatt acttgacttt aagatactct ttaaaactgt
     9001 taaagtagta ttgacaggag acggagctag ataattttaa aatattagat tactaatcaa
     9061 tgaaaaagct ctttaaaaag agctttttta ttgtcaaaaa atacaaaaaa gaaaaggaat
     9121 gagaacttat gattaaaaaa atttctacta tattatcgtt agttttgtta atctctattt
     9181 ctagtacgat aggagtattt gcagatgcaa atcccaaaag agagttgata gaagggagta
     9241 taccagagat ttcgacagaa ttaaataaaa gagcatttaa ggattctaaa gaagtaattc
     9301 ttgtaaatga agagtcaatt gtagatagta taagtgcaac acctttagca tatgcaaaaa
     9361 atgctccaat agttgtaact aagagtaaaa atcttggtag agtaacaaga aattatctaa
     9421 aagaactagg tccagagaag gttacgatag taggtggttt aaaggcagta tctaaagatg
     9481 ctgaacgtaa tatagaaaaa atgggaatga aagtagaaag aataagaggg aaagacagat
     9541 atgatacatc tttaaagata gctagagaaa tgtatagaac agtaggattt gatgaagcat
     9601 ttttacttag ctcaacaaca ggattagaga acgccatatc tgtatattct tatgccgcta
     9661 aaagtggaat gccaataata tgggctaaag atgaagggtt tgaggaacaa attgatttct
     9721 taaaaggcaa gaatcttaaa aaaatatatg cattaggtga ttcaaaagag tttattgcag
     9781 agattgattc taacttaaaa aatatagaag gaataaagca aataaataag tcaagtacaa
     9841 atgttgattt aataaagaag ttttatgatg aaaaagatat aaagaaaatc tatactgcta
     9901 gattagactt tggtagtaga tctgatgtaa acgaatatat ttctttggga gtagtatcag
     9961 caaaagaaaa tatgccaata ctgatttgta gtgataactt aagtcgtgca caagataaat
    10021 tcttgaaaga tagcaatata aatgatgtag ttgaagttgg gtatacagta ggtgattata
    10081 gtctatttaa gagcatattt aatctaacat tcttatcttg tatagtatta atactattat
    10141 tactattgat tacatttagg gcacttagat atgagtcgaa atagtttttg atttataagg
    10201 aagcttttca taggttaaat ttacttaatt agaataatgt ttataagcag ttttaaaagt
    10261 tctactttta gagtttaaat tagataagga gaaagaagat gtcaaaaaca gctaaagcag
    10321 cattgtggat tatggcagcc actatgtttt caaaagtatt aggtttcctt agagaacttg
    10381 tacttgcaaa tttctatggg acaggtatgt atgcagacgt atttgtatta acattaaata
    10441 tacctggttt aatcatagca gtcataggct ctgcagttgc tacaacttat atacctatgt
    10501 actttgagac aaagaaaaga ctcggagatg aaggtgcctt aaaatttact aataatgttt
    10561 taaatatatg ctatataatg gctatagtaa tagctattat tgggctttta tttacagagc
    10621 aatttgttac agtatttgca gcaggattta gaaacgaccc tgctaagttc caagcagcaa
    10681 tattatttac taaaataatg atttcaggag ttttattcct gagtggaagt aagatattta
    10741 gttcgttttt acaggtgaat gacagttttg taattcctgg gcttatagga atcccatata
    10801 atattataat aatagcagca atagcactaa gtgcaggtaa aaatgtatgg atactgccag
    10861 caggagcatt attggctatg gcgagtcagc tattgtttca actgccattt gcgtttaaga
    10921 agtcctacaa gtataagcca tatataaatt taaaggatga gtctataaaa gagttagtca
    10981 acctagtatt gcctatgttg gtaggagtag ctgttggaca gttaaatata tttgttgacc
    11041 gattattggc aaccactttg ggtgatggaa agttgtctgc tcttaactat gcaaataggc
    11101 taaatgagtt tgttatggca ttatttgtta catctataat aacagttata tatcctaaac
    11161 tagcaaaaat gtctggtaaa gataataaag aaggatttat aagcactatt gtaaaatctt
    11221 caaattgtat tatattggtg gtgcttccta tatctatagg agctattata ttagcagagc
    11281 ctcttgttag aatattattc caaaggggta aatttgatgc gttatcaaca gaccttacat
    11341 ctatagcgct tagattatat tcactaggtt tattggcttg tggagtaaga gatgtcttat
    11401 atagggcatt ttactctctt tcagatacaa aaacgccaat gataaatgga agtatagctt
    11461 taataataaa tatagttctt aatttaatat tgataagacc attgggtcat gcaggtattg
    11521 ctatatcaac tagtacatca aacataatta cagttatatt attatttata tctcttaaaa
    11581 agaaaaatgg atattttgga ggggataaaa ttataaagac tggtctaaaa agtttggtag
    11641 catctggtgt gatggcagta gctactttat tgatatataa taatctatat gcatttatgg
    11701 gttcaggaac aattaaagaa attatatcag ttggagctgg agtattaggt ggagcttctg
    11761 tatatactgt attgatagtt ttatttaagg tagaagagat ggatttagct tttgaatttt
    11821 taagaaaagg aaaacaaaaa ctacttagaa gatagataat taccttgaaa ttttaaatta
    11881 gagtcagaaa ggatgaaaat atggattata agaataatta tgagatgtgg ttaaattctc
    11941 cttattttga tgaacaaacg aaaaatgagc tattaagtat aaaagatgat gaaaaagaaa
    12001 tacaagatag attttataaa aatttagagt ttggaacagg tggtttaaga ggtataatag
    12061 gagcgggaac taatagaatc aatatttata ctgttagacg tgcgacactg ggcgttttaa
    12121 attatatcat gaaaactcaa ggagaagaag gtaagcaaaa gggaatagtt atagcacatg
    12181 atagtagata catgtctagg gagttttgta tagaagtagc aaagacttta agtgcttatg
    12241 gtgtaaaggc ttatattttt gaagaattaa agcctacacc agaactttct tttgctgtta
    12301 gatatttaaa gtgtgctatg ggaatagtaa taacagcaag tcataatcct aaagaataca
    12361 atggatataa agtatatgac tcagatggtg gtcaaatctg tatagatatg gcaaatgata
    12421 taatagcaga agttaataag attgatgatt acagtactat taaaagtata gattttaaag
    12481 aagctttatc taaaaattta ataactatat tagataatga agtagatgat gagtttataa
    12541 aagctgttaa gaagcaagtt ttaagacaaa atataataga tgaatacggg aaaaaattaa
    12601 aaataatata tacacctatt catggtacag gaaataagcc agtaagaaaa gtcttaaatg
    12661 aatgtggctt tgaaaatgta atggtagtta aggagcaaga attgccagat tctaattttt
    12721 caacagtaaa gtatcctaat cctgaagaaa agtcagtgtt taatatagct attgaaatgg
    12781 caaagaacaa tggcactgat ttgataatag gaacagaccc tgattgtgat agagtaggta
    12841 tcgttgtaaa agattcaagt ggtgaatatg tagtcttaaa tggaaatcaa gtcggttcac
    12901 ttttagttag atatatatta gagagtttag ttgaagaaaa taaacttcct aaaaacaatc
    12961 ctacaataat aaaaactata gttacatcag aactaggtgc aaaaatagca aaggcttata
    13021 atgtagattg tttaaatact ttaacaggat ttaaatttat aggagaaaaa ataaaagcgt
    13081 ttgaagaaag caatgataga agttttataa tgggatatga ggaaagctat ggttacttaa
    13141 ttggaactca tgctagagat aaagatggtg ttgtatcttc acttatgata tgtgaaatgg
    13201 cagcatacta ttcttcaaaa ggtatgaact tgtatgaagc tttgatagat acatataata
    13261 aatttggata ctacaaagag gacttaaagt cagtaacttt aaaaggcata gatggaataa
    13321 aaaaaataaa agagatgatg ctttacttta gaagtgttaa aatagataat gtggctgatg
    13381 taaaagtaga taaaatttta gactataaag atggtgttga tgatttacct aagtcagatg
    13441 tacttaaatt tttacttgaa gatggctctt ggatagctat aagaccttca ggtacagaac
    13501 ctaaaattaa attttacttt ggagcaaatt cagacaatca agaagatgta gaatttaagt
    13561 tgaacaattt aatatcttat atattaaatg tagtggattc tatataaaaa gctaagggga
    13621 gataaacaat gaaagtatac aatgtcataa tggccggagg aggaggaact cgtttctggc
    13681 cacttagtag acaagaagta cctaaacagc ttataaattt aagtggagaa gatgctttaa
    13741 taaacgaaac tataaacaga atagattctc tagcaaaaaa agatgattta tttatagtaa
    13801 ccaatgagaa gcaattggaa gctttaaagg atatagtaaa agataaatgt ttggatagta
    13861 atatattgcc agagccatgt gccagaaata cagcagcagc tataggcttt gcagcattta
    13921 acataatgaa aaaatatggt gatggtgtta tgtgtgtata tccagctgac cattatataa
    13981 aagatgaaaa agaatttaaa tctattttgg aaaaagctat ctatatagca gaaaataatg
    14041 ataaattagt aactattggg ataactccta catttccatc aacaggatat ggatacataa
    14101 attttaatag agaaaatact atagaagatg ttgcatatga ggtagtggag tttgtagaaa
    14161 aaccaaacta tgaaattgct aaagaatatg taaactctaa aaagtatgta tggaatagtg
    14221 gaatgttcgt atggaaggta tctaaaatac tagaagattt taagagatac ttgccaaaag
    14281 tatatgaaaa attagaagat ataagtaaat acttaggaac aaaagaagaa atggaaaaaa
    14341 taaaagaaat atacccaact atacaatcaa tctctataga ttatggtatt atggaaagaa
    14401 gtaatgatgt tatagtagtt cctggtgatt ttggatggaa tgatgttggt tcttgggatt
    14461 ctctaggtgc aatatatcca actgatgatg aaggtaatat caaaagaggt gaaaatatta
    14521 ctatagatac taaaaattca attatatatt cagatgacaa attaatatcg acaataggta
    14581 ttagtgattt gatagtagta tctacaaatg atgcagttat ggtttgtaga aaagataaag
    14641 ctcaagatgt caaaaaaata gtagagcagt taaaagaaga agatagacaa gaatatatgt
    14701 aggaggtgtt catttgattc ctaaaaaaat acattatgta tggtttggtg gtccaaaagg
    14761 aaatatagaa aatatatgta taaattcttg gaaagaaaag cttccagaat atgagatagt
    14821 agagtggaat gaaaaaaact ttgatataga gaaagaaata aaaggaaata agtttttgga
    14881 agaatgttat aaaagaaaac tttgggcatt catatctgat tatacaagaa taaaagtact
    14941 ctatgaacaa ggtggagttt atatggatac agatatgcaa atattaaagg atataactcc
    15001 tcttttagaa aataataggc taatctgtgg gtatgaagat gatagagagt atataaatgg
    15061 tgctataata ggtgtagaaa aaggacatcc ttttttaaaa gacttattgg agtactatga
    15121 aaaagaagta cttacttctt cattgtttac aataccaaag ataatgactc atcttatgga
    15181 aaagaattat aagaagattg acccaaataa ttatgaagaa ggaatacgtg tttacgacaa
    15241 agaatatttt tatccttttg gatttaaaga agactttaca ccagaatgta taacagaaaa
    15301 cacttttggg atacattggt ggggaaaaag ttgggctaaa aagagaaatt atttcttaga
    15361 aagcaaacac ttaacaggtg taaataagat atggaagtgt tgtaaaatat ttgcaagtaa
    15421 tactttacga agctaaaagg gagaaagtaa aatgaagact ttaaatgatg atagaaatat
    15481 tatgattaga aaatatcttt atatatttgt tttgtttatc atattactta gaaagtatat
    15541 gatatcattt attgacccaa atatggatat agggatgatt aaatcagcgt tattttattc
    15601 ttcaatagga atactaatgc tacttttttt atttgataag agaaaaagta taacagaaat
    15661 ggtactagtt ggagtttgtg tcttacttta tttattaaat agggaaggag ctatattatt
    15721 aatcgtttta ttagctgtat cagctaagca aatagatgat aaatttatag ttaaaaatta
    15781 tttaataata tcagcatgtt ttttaatggt agctatatta ttatttaatc tatttccttc
    15841 attaatattt aatcaggaag tccactatag atatatagaa aaaatagata tgcttgttac
    15901 aagaatggat tttggacttg gtaatccaaa tagtgtattt tatcatatgg ttactatata
    15961 tgcagcatat atattcttaa gatataaaga ttataataaa tgggatagaa taattttatt
    16021 tggttctgca ttttttgttt atcaaaccac atatagtaga actggatttt tcactatatt
    16081 agcaggatta atatttgtag aaataataag atggatagat ataaaaaaaa taaaaggact
    16141 accaatgctc ctaaagacat taccaataat acttacttta tttagtgtaa ttattggtac
    16201 agtatttgat aaaagcactt tattaaatag attattagca agtagaccta agttctggca
    16261 tgtatacttg gctgaaaagg ggaactttct aaaacctttt ggaaattcat atagtcctgc
    16321 tataaaagca actaatccat tagatagttc ttatgtatat ataattagtg tactaggagt
    16381 agttgcttgt atattattta tgtatttgat gtataaagga atagaaagct ttatagaaaa
    16441 agataaaaaa gcatatttag tagctttatt tatattttta ctatactctt ttgcagaaaa
    16501 tttattatta gaagcttcat ttagttttgc agtagtatta ctaataaaag aagtgatatt
    16561 aaatgataaa agggaaatag atttgtggaa gatgaaaagt aggaggtagt aatgttaata
    16621 tcattaataa tgccaacatt aaatagatat gatgatatat acttacttat ggacagctta
    16681 gaaaatcaaa cttacaaaaa ctttgaactt atagtagtag accaaaatga taatagcaaa
    16741 gttaaagaaa tagttgataa atacattgat aagttagata taaagtatat aaaaagctct
    16801 aaaaaaggat tgagttataa cagaaatgta ggcatagaca atgctgtagg gcaaattata
    16861 ggtttccctg atgatgattg tgtctacgaa aatgatacat tagaaaaagt tataaatttc
    16921 tttaataaaa ataaagatta taaaatatac agttgcaaaa ctatggattc aaataaagtt
    16981 gatgcattta agaaaatgta tgatggaact tgtgatatca caagttccaa cgttttggat
    17041 actataacat ccataacttt ttttattgat tttgaaggta aagattatac aagatttgat
    17101 gagaaattgg gtgttggtgg agagtttggt gctggtgaag agatagatta tgttttaaac
    17161 ttattgagtt taggttttaa aggaaaatac tttggaaatg atataattta ccatcctgca
    17221 aaaaaacatt ctaaatctaa agaaaagtat caaaaagatt ataactatgg aagaggcttt
    17281 ggagcgcttt gcaaaaagga aatagtctat agaaaaaatt ataagtttgc aaaagttatg
    17341 gtatcaaaac ttgtaagaaa tataggaggt cttatattga gttccaatag agattatcat
    17401 agtgccacta taaaaggaag aattaatgga tttagacagt acaagttata atgaggatgg
    17461 tgtttatgga caaggttaaa tttttaataa atatgctttt ggcttttttt atatatccat
    17521 ttaataagca taagtttaat ggtagagata tctggcttat aggtggacat tcaggggata
    17581 tatacaatga taattcaaag tttttttatg agtatatgct aaaagaacat aatgatgtag
    17641 aaacttattg ggtagtaaat aaagacagta aagtatttga taaaattcca ggcaaaaaat
    17701 taataagagg aagtgtagaa aactatctgt attattacaa ttcaaaagct atagtatttt
    17761 cacatgcacc atcagcagat atagcaccat acaattttgc tgtacctgtt cttaattatt
    17821 ttcataaaaa aacgataaaa gtgtttttaa atcatgggac tataagtttt aaaaaaagaa
    17881 aacctatgaa caaaaagttc aaaaatatta tagataacct atataaaagc tataatatag
    17941 ttacagcaag ttctgaattt gaaagaaatg ttatggtaaa tgattgggga atgttagatg
    18001 actcagttta tataattgga aatgcaagat atgacaattt accaacaaat gaagttgcac
    18061 aaactcgaga tatattatat actcctacat ggagagattg gataaaattt agttcaggaa
    18121 aatttacgga tacagattat tttaaaaata taatgaattt tttaaatgat gacaaattaa
    18181 ataaaatatt agatgagaaa gatataaatg taaaaattta tatgcatcat cttatgcatg
    18241 agtttataga tgatataaaa gaaaatataa caggaaaacg aattgtgttt ttagataaag
    18301 gggtaactct agcaaatgaa atcagaaaat cagctgcaaa tataactgat tattcaagtg
    18361 tagccataga ctttttgtat atgaatagac ctatcttgtt ttaccaattc gatttggatg
    18421 aatatatgga aaaagttgat tcatatatag atttaaaaag tgaaatgttt gggtctttgg
    18481 cttataataa tgatgaagcc gtgaataaac ttattgatat tattgaaaat aattttgagg
    18541 ttatggataa ccaaaaaaat gaaagaaata agtttttcag atataatgat aataagaact
    18601 gcaagaggat atatgattgt gtattaagta aaattaaata aatattttat aaatgatgag
    18661 gaaggtaata tgaagaagaa tttagtatct ataattactc ccatgtataa ttctgaaaaa
    18721 tttattgaag caaccataaa atcagtatta aaccaaactt atcaagaatg ggaaatgtta
    18781 attattgatg attgctcaac agataatagt cctaatatag tcaaatctta tatgcaacag
    18841 gatagtagaa taaaatgtat aaagactgag actaataagg gtgtctctaa tgctagaaat
    18901 ttagcactaa gtaaggcaac aggacaattt atagcttttt tagatagtga tgaccaatgg
    18961 aatagtagta agttagaaaa acaagtaaat tttatgttag aaaatgacta tgtaatttca
    19021 tttacttcat atgaactgat ggatgaaaat gataaaaaat taaacaaagt aataaaagtt
    19081 ccacctaatg tagattatag aagattatta aaaggaaata tcttgggatg tcttactgtt
    19141 gtgattgata agtctaaatt ggattttgaa ataagaatga gtggtgtaag acatgaagat
    19201 tatgttttat ggttatcgat attgaaaaaa gggcatattg ctcatggaat aaatgaagtt
    19261 ctagcattat atagaaaatc tagcaattcc ctaagtggta ataaaataaa agctgctatg
    19321 tggacttgga atatatatag aaatatagaa aaaatacctt tatacaaagc tatatactac
    19381 tttattaatt atggaataaa cggaatcaaa aaaagttaga cagagaggaa gatttaatta
    19441 atgtataaat ataaatttac tgtatttact ccgacgtata acagagctca tttacttgaa
    19501 aatttgtaca atgatttaaa agctcaaact tatgatttca atgattttga atggttgatt
    19561 gttgatgatg gaagtagcga cagtactaaa gagttagttg aaaaatttat atcagaaaat
    19621 aaattaaata taagatatat atacaaagaa aatggaggaa aacatactgc aataaatcta
    19681 ggtgtaaaaa atgcagatgg agagctattt ttcattgtag atagtgatga tggtttaatt
    19741 aaagattctc ttgaaattgc taatgatgag tgggattctt tagagaataa agaaggattt
    19801 agtggagttg ttggactttg tgtatatcca agtggagatt tgatagggac agaaatgcct
    19861 gaagataaga aaatatgtca ctttgcagac ctatatttta agtatggcgt taagggagat
    19921 aaaagcatag tatttgtaac tgatgagctt ataaaatttc cttttccaga aagaaaagaa
    19981 gtgagatttt taccagaaag tgtagtatgg aatgaaatgt ctaaatacta taaagttata
    20041 tgtgtaaata aacctatgat aataagagat tatttggatg atggtttgac taagaatata
    20101 ttaagtaaaa atgcattaag aggtagagca ttagaatttt tatatttaat aaatcaaaat
    20161 acatatccat taagtagata tccatatatg tggataaaaa attacataaa tttagccaga
    20221 tactcattgt tgtctgatag tcattatttt ggtgaattaa gaaaagtatc tgataaattg
    20281 ttgtatttag cattattccc attaggatat tacaaatata ttggacaaag aaaattagta
    20341 tctaagtaaa cttgttggta tagtactgct agttgctata taaggagagt aaaaatatga
    20401 atgagccttt agtatcgata attactcctg tttataattc agaagagttt ttatcagaga
    20461 cgataaagtc aatccaaaat caaacttata aaaattggca gcttttatta gtggatgatt
    20521 gttctaagga caattcaagt gaaattataa aaagttttcg aaaagaagat gctagaataa
    20581 aatatataaa gcttgaaaaa aattctggag ctgcagtatc tagaaatgtt ggtattaaga
    20641 atgcggaagg tcgatttatt gcatttgtag atagtgatga tttatgggat agtagaaaat
    20701 tagagattca gatagaatat atgttaaaag aaaatgtagg tttttctttt acatcttata
    20761 gatatatgag acaagatggg tcaaaaacga ataaggttgc aagagctcct aagaaaattg
    20821 actatgaagg attacttaga aatactataa taggatgttc tacagtggtc attgataagg
    20881 agattgtagg agagttcagc atgcctttgg taagaagagg acaagatact gcaacctggt
    20941 tacagttact taaaaaggaa aaatatgcat atgggattca agaagattta gtgaattaca
    21001 gattagttgg aaattctata tcaagtaaca agataaaagc attaaaacga acttggaata
    21061 cttatagaaa tgttgaaaat ttaagtttac caaaaagtct atatgtattt tgtttctatg
    21121 tttttaatgc cattaaaaaa agagtataag ttttatatac ttggaggtaa aaaaatgaaa
    21181 atagctatag ctgggacggg atatgtaggt ttggttacag gtgtttgtct agcagaggta
    21241 ggcaatgaaa atgtagtctg tgttgatgta gatgaacaaa aagttaaatc aatgaaactt
    21301 ggaatagcac ctatatatga agaaggccta gaagaactta tggttaaaaa ttacaacaga
    21361 ggaagaatag attacactac agactataaa aaagcttatg aagatgtaga tgtaatatta
    21421 atagctgtag gtacacctga gagaagtgat ggctcagcca acctagatta tataaaggca
    21481 gttgcaaagc aaatagctga aactgtgaca aaagatactc tagtagtaat aaaatctaca
    21541 gttccaattg gtacaaatga agagatagaa gattatataa atagaaacct aaaaaatgat
    21601 gtaaaagtag agcttgcatc taatccagag tttttatcac aaggaacagc agtaaaagat
    21661 actctacatg cttcaagaat cgttataggt gtagaaagtg aatgggctag agaaatatta
    21721 gaggaaatct ataagccttt taatcaacct ataatagtta caaatagaaa tagtgctgag
    21781 atgataaaat acgcatcaaa taacttctta gctcttaaaa tatcatttat gaatgatatt
    21841 gcaaatcttt gtgaaatagc aggagctaac atagaagatg tagctttagg aatgagttat
    21901 gatgatagaa taggaagtaa gtttttaaag gcgggaatag gatatggtgg ttcttgcttt
    21961 ccaaaagaca caaaagctct tcactggtta tctgaacata atggttatga attaaaaaca
    22021 gtaaaagctg caatagaagt taatgaaagt caaaaactta aattagttag aaaggcatct
    22081 aagttagtag agagctttca agatatgaag gttgctgttt taggtttgac ttttaaacca
    22141 gatactgatg atataagaga agcaccatct ataccaaata taaaatattt gctcgaaaga
    22201 ggggcaagag ttactgtata cgacccaatt ggtgtaaata atactaagaa aatatttggt
    22261 gactctatac tttatgctga ttctgtagat gatgcgatag aagatgcaga gatatgtttt
    22321 ataatgacag aatggaaaga tgtattaaat tatgatatac ataagtataa ggaaaagatg
    22381 aaaaatcctt tagtccttga tggaagaaat tgttataaaa ttaaagatat ggaagattta
    22441 ggaattgagt attattcgat aggaaggtaa atattatgaa gactgtttgt tatttagctg
    22501 atgggtcaaa tcctcatact ttaaaatggt gtagtttttt taaaaataaa ggatatgaca
    22561 ttcatgtaat ctctttgaat ggaggtcaca tggaaggaat aaaaatttat aattttggtt
    22621 ctaatgtaga agaactaaaa aatgaaaata tttctaaaaa aacgggatac ttaggttcaa
    22681 taaagcagat aaagaagcta gtaaatgaaa taaagccaga tatattgcat gcacagtatg
    22741 caagtagtta tggatttata ggaagtctac ttgggtatca tccatatatt atttctgttt
    22801 ggggtactga tatttatgat ttccctaata atggttttat acaaaaacaa attataaaac
    22861 ataactttag aaaagcagac tatatctttt caaatagtag agatatggct aaagaggcta
    22921 ataaatatac agctaaacat gtagatgtaa ccttttttgg agtagatatg gataggttta
    22981 agcctatgga agtagaaaaa gaagacgctt ttgtaatagg aattataaag agtttagaaa
    23041 aaaaatatgg aatagaatat ttaatacaag catttaagat gcttaaagat gaatataaag
    23101 ataagaaaat aattcttaaa ataggtggct ctggaagtca gatggacaac ctaataaatt
    23161 tagctaaaga attgggtata gaaaatgatg ttcagttttt aggaagaata tctccagaaa
    23221 atgtaagcaa gacttttaat tcttttgatg taactgtatt tccttcttta agagagggat
    23281 ttggagtggc agctatagaa tcagaagcat gtgaagtacc tgttatagtt acaaatgtag
    23341 gaggacatcc agaatctgta tgggaaaatg aaactggctt aattgtagaa ccaaaacaac
    23401 cagaagaaat aaaaaaggct ataataaaac taatggaaaa tgatgaactt agacttaata
    23461 tgggtaagaa agggcgtcaa tttgttagag aaaattatga ggttaattta aactttaatg
    23521 atatagaaaa aatttatgat tctatatttg ataaatataa aaaataaaat gaaaaaatac
    23581 agcaaaagat agatgttgtt ggctatgctt aggtgcgtag cttttgctgt ttaaaggagg
    23641 gcttctagtt atgcgagaaa gtatagattt agagaaagaa agctttttta ataggctttt
    23701 taaaaaatat aaatttagac atttaacact attaattcta gatatttgta gcgtactagt
    23761 agcgtttcga atgtctttaa gcttgacagg taatttaaat gcatttacca ctaatgatat
    23821 aataatttca gtgtgtatat atatagtact tcatatagta tcatttagat tgtttaagtg
    23881 ctacaacaca ttatggagat atgcaggaga agaagaaatt atatctattt ttatggcaac
    23941 tttagcttat ttaattccga tttatataat aaataaatta ttagggtttg attatcctat
    24001 aatgttttat gtattaaata caatatttat tataatgttt acaagtggcg caagaatagc
    24061 ctatagagct ataagaatag tcatgaacaa gacatattct agaggaaagg tttcaaatat
    24121 ccttataatt ggtgcaggag atgcaggaga aatggttata caggaactaa aaagaaatcc
    24181 agaacttaaa aaagtagcag tggctataat tgatgatgat aaaaataaaa ttggaagaat
    24241 aatccataat gtgaaaattg taggaacaac ttcagatata aaagatgtgg tagaaaagta
    24301 caatgtagat gagataatct tttcaatagc aaacatagag aaacgtagaa aaaaagatat
    24361 tattgatata tgtaaaaaca ctaactgtaa aataaagaca ataccaggaa tttacgaaat
    24421 tatagatgga aaagttgata taaaacagat tagagaagta gagatagaag acttgttggg
    24481 tagagagcct ataaaaacaa atttaagaga gataagtaat tacattgagg gaaaagtaat
    24541 cctaataact ggaggaggag gctcaattgg ttcagagctt tgtagacaga ttgcaggatt
    24601 taatcctaaa gagcttatta tagttgataa ttatgaaaat aatgcttact caatacaaca
    24661 agaattactt agaaaatata aaaataaatt agatttgaag acagtaatag catcaataag
    24721 agaagaaaaa agaatggatg aaatatttaa taaatataaa ccagaagtgg tatttcatgc
    24781 agcagcacat aaacatgttc ctcttatgga atcgagccct ggcgaagcta taaagaataa
    24841 tatatttgga actttaaaca tagctgactt gtcttcaaaa tatagagcta agaaatttgt
    24901 ccttatatct acagataagg ctgtaaaccc tactaacata atgggagcta ctaaaagagc
    24961 tgctgaaatg attatacaga ctatgaatgc tgaaagccag actgaatttg ttgctgttag
    25021 atttggaaat gtgcttggta gtaatggtag tgtaattcca ctttttaaga agcaaattga
    25081 agatggcgga ccagtgacag ttactcatcc agatattatt agatatttta tgacaatacc
    25141 agaagcagta ggcttagtta tacaagctgg ggctatggct aaaggtggag aaatatttgt
    25201 gcttgatatg ggagaacctg taagaatatt ggatttagca aaaaacttaa ttaaattcag
    25261 tggatttgag ccagatgttg atataaaaat tgaattttct ggtcttagac caggagaaaa
    25321 gttgtatgaa gaactactta tgtcagaaga aggtctattg gatacagagc ataaaaagat
    25381 ttttattggt agaccaatag atgttgatag agaaaaaata acaaaatact taaaactttt
    25441 aagagaaatt actaacaatg aagaggttga aaaaatagat ggtattatga gggaattagt
    25501 accaacttat attaaaccag aagatgctaa tatcaaagaa attgcaacaa ctagagaaaa
    25561 gtagaatata tttctaattt gtaaccaggg ggagcaaaaa gaaacaaata tatactaaaa
    25621 agaaacaaaa gattacaaaa agattacaaa aagattacaa aaaaggttgc aatttatttt
    25681 gatgtaagat agaatgttaa ttaggaattg gaaacgaagg aacaaaatgt taaattttcg
    25741 aaaggattag gtatttgaga ttatgatgaa tattaaaaat aaaaaacata tattgaaaaa
    25801 atttatagct atggtgttaa tagcaggagt tgtcacagta gaagcaggag caataacggc
    25861 tagtgcagca gagccaacta attcacctat gagtgcaaca gtagaccagt gtgatttttt
    25921 aaatgtaaga agtggagcta gtgcaaatga tgcagtagta ggaaagataa acacaggaga
    25981 caaagttgaa gttttagaat tacattcaaa tggatggatt aaaataaaaa gtgttgacaa
    26041 tgttacagga tgggtaaatg gagattattt aactattcaa ggtggaaatg tagatgcaaa
    26101 ggtacaaaat gttttaaact tagcatttaa gcaacaaggt aagccatata aatggggagc
    26161 aactggacca aattcttttg attgttctgg gttcacttct tatgtctata aaaatggagc
    26221 aggagttaat ttaccaagag tatcaagatc acaagcaaca gtaggaaaga aagtatcaag
    26281 agcagaatta aaaccaggag atttagtttt ctttggttca ggtggttcaa taaatcacgt
    26341 tggattgtat gtaggagatt ctaaattcat acattcacca caaacaggag atgtagtaaa
    26401 agttactagc atggctccag gaactaatta tgcaaaaaga cttataactg ctacacgtgt
    26461 tttacaataa taatagatat tgatttacat aggattgaat attaacatta aatatataat
    26521 tacatttaat gttttacata gagatttaag agtttagtaa tattaaaata gtgatgaacg
    26581 ttataaaaac agcaaagaag ataaatttct ttgctgtttt ttttataata aattatttca
    26641 tattataatc aaatatcaaa tataaatttt aactatatta ttcaatattt gacagataat
    26701 atgaatttta gatatactta ataagaagta tattgtagaa aaaataaatt taaaaaatta
    26761 agggggatga aatgaaaaaa ataagtatat tagtattatc attgataatg acacttacta
    26821 tgtgtagtgt aagttcattt gctgattcat caaatgataa ggaaatgaga gctgcttgga
    26881 tatctacagt ttataattta gactggccta agactaagaa taatgaagcc aagcaaaaaa
    26941 aggaatacac agatttattg gacaaattaa aaagtgtagg aataaataca gcagtggttc
    27001 aagtaagacc aaaatcagat gctttatata aatcaaatat aaacccatgg tctgaatatc
    27061 ttaccggtac acaaggtaaa gaccctggat atgacccatt accattttta atagaagaag
    27121 cacataaaag aggaatggaa tttcatgcat ggtttaatcc atatagaata actatggcag
    27181 atgagagcat agataaattg ccagcaaacc atccagcaaa gaaaaatcca agctgggtag
    27241 ttaaacatgg aaataagtat tactacgacc caggtttacc agaagttaga aagtacatag
    27301 tggatagtat agcagaagta gttcaaaatt acgatataga tggagttcat tttgatgatt
    27361 acttctatcc aggagtaagt ttcaatgata ctgcaacata ccaaaaatat ggaaaaggac
    27421 aaaataagga taattggaga agagaaaatg taaatactct acttagagat gtaaaagcgt
    27481 ctataaagag tataaagcct aatgttgtat ttggtgtaag cccagcaggt atatggagaa
    27541 ataagagtag tgacccaaca ggttcagata catcaggtaa tgaaagttat gtaggtacat
    27601 atgcagatac aagagcatgg ataaaacaag gattgattga ctatgtagtt ccacaacttt
    27661 actggccaat tggtcttaaa gcagcagatt attctaaatt agtggcatgg tgggctaatg
    27721 aagtaaaagg aacaaatgta gacttataca taggacaagg tatatataag caaggtcaat
    27781 cgagttatgg tggacaaaat atagcaaaag aaatagtaca acaagtaaca ttaaatagaa
    27841 agtatagtga aataaaaggt agtatgtatt tctcagctaa agatatagca aatagtactt
    27901 ctatacaaaa ggatttaaag agtttatatt ctagtagtga agaaccagtt actccaccat
    27961 ctaatgttaa agtggagaaa ttaagaggcg acgaaagata tgacacagca gtagcaataa
    28021 gtaaaaaagg ttgggctaca aattcagata cagtagtatt agtaaatggg tactctatag
    28081 ttgatggtat aacatcaaca ccacttgcta catcaaatga tgctcctata ctattggtaa
    28141 ataaggataa tatacctaca tccactaaga atgagttaaa aagacttaat ccaagtaaag
    28201 ttattttaat tggaggaaat aactctattg gagataaagt tgagagtgag ataaaggata
    28261 cattgtcaaa tgtatcaata aatagagttg gtggttcaga tagatatagt acatctttaa
    28321 tgatagcaaa agaattagta aaaactaatc cagtagaaaa actatatata acaagtggta
    28381 caggtgaagc agattctctt tctatagctt caaaagcagg agaagaaaag caaccaatag
    28441 tattagtatc aaaagataat gtaagtgatg aagtttacaa ttggatatca gatttaaaag
    28501 taaaagatgc ttattttata ggtggtaatc taagtatatc tgattcagta ataaataagc
    28561 tggataaggt cattacaaat gatgtatcta aaaatagaat agctggagaa aatagagaag
    28621 aaacaaatgg aaaagtaata caaaaattct atccaaatgc tgaatattca tcaatgtttg
    28681 taagtaaaag taatcaattg gtagatgcat taacatcagg tcctttagcg gctaaattaa
    28741 aatcaccagt agttatgctt ggaaatagtg taacatctgc tcagaaaact gctttagagc
    28801 ctaagaaaac tactctagta tacgaagctg gagatggtat aaatcaaaac acattaaaca
    28861 ctttcttaaa cttagttaag taataaaaaa gttaatttaa aatacagagt attttacaaa
    28921 tgtagattaa aatgaaaatt atcatgataa attagaaaat aaaaaagaac tatatgcatt
    28981 ttgtaatcaa gtgcacacag caacttgaaa ataattatgc gatatagttc ttttttagta
    29041 attaatctta tactttttaa taaactttat gttgaatttt ttattgttta aactctatgt
    29101 cattaaatat aaaatcgtgt aatatgtcta aagtatctgg gtcaaatcta agaacccatc
    29161 cagcttttcc atatatacca cctgtactgt gaatttcatc atcaatagga aattcaaatt
    29221 gcttaatatt taagtcgccc atttttaaaa cttgagctcc taaagaaagt attgcattag
    29281 gcttcatgtt agtcttaaca tatggaagaa ctgcatctaa taaacctgga tatttagtaa
    29341 caggtaaagt ttccgttttc ttgattatag cttgtataat ctgtctctgt ctgccatctc
    29401 tagcaaaggc tgtatcgttg tgtctgatac gtgcaaaaga tagtgcctga tatccattta
    29461 gagtctgctt tccagagttt ctaatgtatt gtatgctacc tttatcatca cttttattcc
    29521 atttataagt ttcaggaata aatttattta gttctcgtat ttctcctttt tcaacagtaa
    29581 cctcaacgcc accaatagca tcaattatat acataaatga ttcgaaatta acacaagcat
    29641 aattttgaat atcaatatta aaattctctt caattgtttg tattaataaa tcagcttgtc
    29701 cataagcata agcatgagta agtttttgtt taccatgacc agggatgtct acatagctat
    29761 cacgagctaa tgatgtaagt ttgatatcat tgtgtttgtt atcaatagta agtatcatca
    29821 tagcatctga ccttgaagaa tcttcatttg gtctagcatc tgttcccata agtagtatgt
    29881 taattatccc atcttcattt ttatggtcat tgttatccaa taaatcacta cttatgctcg
    29941 agtcatgaat agcagataat ttataataaa aatatccata gacacttata gggaatatta
    30001 ctaccaagaa agccagtagt ataacaaatt tctttaattt tgacaaaagt accccttctt
    30061 tcttcttttt cctgtatatt ttttaatagc atacacttaa ttatattaaa gtattgagat
    30121 atattcaata cttgtttcag ttacaaaaaa aagacaatga tataatttat aagaaaattt
    30181 atcgacctat atatatagtt aaaagtatat ataatatatt ttttaaaagt aatttatatt
    30241 ttaaaataaa aacacacccc ataaatacaa agtaatttgc atttaagagg tatgtattta
    30301 tcatcaaatt attggtttgt tttggaattt ctaatcttca accataatat ctttaaatat
    30361 gaaatcatgc attgcatcta gttcatattc ctcaaaaggt attacatagc ctgcattacc
    30421 tatttttcta ccattttcag tagaaagagg aaactccata gatttcaaat ttaaatttcc
    30481 tatacttaaa agttcttttc ctaaagatat tatttcatta ggattcatat tagtttttac
    30541 atacggaagt attgtgttaa ctagattagg atatttagtg actggtaaat ccttaacacc
    30601 atttattaaa ctctgtataa cacttctttg tcttctatct ctttcatctg tgctatcatt
    30661 ttttcttata cgagaaaatg caagtgtctg atatccattt aatttttgct caccagaatt
    30721 tcttatatat ttaagagaac ctttattgtc atttttattc catttataag tttcaggaat
    30781 aaatttattt aattctctta tttcactctt atcaacagta acagtaactc cacctaaagc
    30841 atcaactata tccataaaag agaaaaagtc aactacggcg tagttttgta tatcaagttg
    30901 gaagttttct tctatagttt ctattaataa gttagcttgt ccatatacgt aggcatgtgt
    30961 taatttttgt tctccacgtc ctggtatatt aacataagta tctctattta atgaagttag
    31021 cttaagactt ttatttttat tatcaatagt aagtatcatc atggcatcag aacgagaaac
    31081 ttcttctcct ggtcttgcat ctgtacctaa caataatatg tttgtgatat tttcttcgtt
    31141 tttatagtca ttactactaa gcgcctctgt atttatacta tcatcttgta tagtttttaa
    31201 tttagtaaaa acatatccat atatactaac aggaaatgct ataactaaaa gggctagaaa
    31261 tataacgaac tttttgagtc ctgacaataa tatcccctac tttctaaatt ttttaattac
    31321 acatagttaa ttatattaaa aatttgttac ataagcaata aaaaacacaa taaattagca
    31381 taagtttgtc ataatataat tatttttata gtattttata gaagaaagtg tgtagttatt
    31441 attgatttta ttggaatata attgtatgaa gacttaaatt tttataaact aatgtgtata
    31501 ttgaaaaaaa tattttcctg aatgtagtta tagcatctta tgaaaggtgc aaattgtaat
    31561 ttaaaatttt tagtgtataa taagaattga aaattcaaac cgataaaaat taataaaaaa
    31621 taattataaa ttaataattt gggggaggaa atgtatgata aaattaatag caacagattt
    31681 agatggaact ttgttagatg aaaagagcga aataaatcca gagttttata aagtatttaa
    31741 aaaattaaga gagagaggga taatgttttc tgctgctagt ggcaggcagt atcaaaatct
    31801 tataaaaaaa tttgaagata taaaagatga tatgatgttt atatcagaaa atggaacact
    31861 agtagtatat aaaggaaaag aaatattatc aaatccttta aataaagaat tagtaaatga
    31921 aatcatagag acaacaagaa gtataaaagg gaaaaaaatt gtaatgagtg ggaaaaaata
    31981 cgcttatata gaaagcaaag atgaagcgtt tatacaagag gtcagtactt attatgcaaa
    32041 gtttaaaatt gtagaagatt tgacgaaagt agagggagac atattgaaga tagctgtatt
    32101 tgacttcaaa ggtgcagaac ataataataa tatctacttt gaaaagtttt ctgatagagc
    32161 tcaagtatgt atttctggag tggagtggct tgatttaact gcaaaaggtg caaataaagg
    32221 gagtgccata aaaaaagtac aaaaaatgtt agatataaaa tatgaagaaa ctatggtatt
    32281 tggtgaccag ttaaatgatg tggaaatgat gaaaagtgcc tatcatagtt atgccatgga
    32341 aaatgcaaat gaacatttga aacaaattgc tagatttaga gcaaaaagaa atactgaaaa
    32401 tggcgttgta gataagataa aagaggttat aaaaattgga tagtcatatg tatagatgaa
    32461 aaagattatt ttgaagaaat caaaaaaata tcaatgtaat tttgataaat aagtttattt
    32521 atgcgaaaat tacattgata tttaataaac atcaataata gatatttatt tttttatgat
    32581 attcagtatt ttgttttcta tttgagttgc attttcagca gaaattaaat aaacatatct
    32641 acctgccttc tcaattatag tattatttgc tatttcagaa ttgatttttt ctccatgtcc
    32701 ttctccaaaa ggtgcttgta tcatatcttt tttataattt tctagagttt tatagatttt
    32761 atctacctcg tcagttttta taacgataat atcttctaga gataattttt cagaagaatt
    32821 aattacaaaa ccttgaatta tgtcttcctc tacatcatta aaatagttaa aatcctttgc
    32881 atcaaagatt tttgattcct ttataagtaa atcagaagat tttaatgctt tttttatttt
    32941 tgatgtagaa acgtttttgt aatcaccact tgaagaacaa ctaaccattc ctaatgataa
    33001 gattatcgaa aaaaacaata ttaaaatttt tttcatgata aacctccaag ttttttaaac
    33061 tctgtcttaa attagtttac tacataatta tataaaaata aatgtattta atgttacagt
    33121 tttgattaat aatgtaatat tttgataata atacctattg agaggtgatt agaaatgaga
    33181 ataccaaaac atgtaggaat tataccggat ggaaatagaa ggtgggcaag tcaaaatggt
    33241 atgacaaaag ataaaggata tgaaagtgga atagaccctg gactagagtc ttatagatta
    33301 tgtagagatt taggctgtga agaggtgact ttttatggat ttacaactga taatacaaga
    33361 cgtccatcag tgcagacaaa agcttttaca aaagcatgta ttgatgctgc aaatatatta
    33421 atagatgaag gtgctgcttt attagttgta ggaaatacaa aatcgccaat gtttccagaa
    33481 gaattattac catatactaa tagaattaaa gccaaagaag gtcaaataaa agcaaatctt
    33541 ctggtaaatt atggttggta ttgggactta aataatatat caggagtaga aaatgtaaat
    33601 aaaaataata tacaggatta catacagtca tttgatgtat ccagactaga cttgataatc
    33661 agatggggtg gaagaaggag attaagtggt ttccttcctg tacaatcaat ttatgcagat
    33721 ttttatgtta tagataatta ttggccagat tttaagagtg acgatataaa ggatgcattt
    33781 agttggtatg atacacaaga tgtcacttta ggtggataat taaaaatatt ctgatttaag
    33841 gttgtagagt gttttaaatt attgaaaaaa aaacttcttg atggtaaaat aacactaata
    33901 atatgtaaaa gtgtaaaaat ttataccaag aagggtgaag aaatgtcaaa aggcaataat
    33961 aacaataatt caagaaacaa atctaaaaag accagtcatc cgaatagaaa aaagcgaaaa
    34021 ttaaataaga aaaagttagc aatgttgatt tgctttacag ttttattttt atttattgca
    34081 tttaaggcta ctcaaggtgt agtagctttg gtaaaaagta tggataaaag taataaaact
    34141 agtcaacaac aaaatgttaa ttcagaacaa tttgaccttg gtaatgaaga ggaaaataaa
    34201 aagaaaaaat atactgtatt tatagaccca ggtcatggag gcaatgataa aggaactgaa
    34261 agcaagacca gtaatagata tgaaaaagac ctaaatctac aaattgcaaa aaaattagca
    34321 aataaattat ctaaacaaaa ggatattcaa gtagtagtat ccagaactga tgatacatat
    34381 atatcattaa aggatagagc tatcttagca aataatagtt ctgctgatgt gcttgtttct
    34441 attcatttaa atgcagagaa aaatggtaat acggcaacag gtatagaaac ttggtatagg
    34501 aataaagcta cagatggttc aaaagaactt gcacaggcag tacaaagtac tatagtatcc
    34561 tatgttaaag ttagagatag gggaatagtt gaaaataact ttgaagtact tagagaatca
    34621 aatatgcctg ctatattgat agagtgtggt tttttaacaa caccttcaga ggaacaaaaa
    34681 ataataaatg aaaaatatca agaccaactt gcggaaggaa ttgttcaagg tgtactttca
    34741 tacctagatt ctaaagggaa taagtaagtt aactttactt caatgtgagg ataaatttaa
    34801 aagtttaact gtgtaaattg tattaacttt atttcgtaat gttgaaaaca ttgtttgaat
    34861 ttagaaacta tgaaattaga aattatttta tctatatcta atttcatagt tttttttgca
    34921 aaaaatttat agttataaaa tttaaaaaaa taaatttagt ataatgtaat gtagttattt
    34981 atatgtgatt ttaacttgca ttgatttgct atcaattgtg ctttataatt aatatatata
    35041 aagtttaact gtaagataat ttaaaaaata ggggaattta tatgaataaa aatagtatga
    35101 caaaaattta cagtttaaat aaaataattt ttattataat tggaatttta ggaatagttt
    35161 tacttacaag acatattggg gtagatatta aagttttaat tttaatttta ttaaccttat
    35221 ttagtataaa tgtatttatt tcatatctta aaattaagtt gtatgaggat aaaattaatt
    35281 taggattgat aaataattca gataagttta taaatattac taaagatgag aacttcctaa
    35341 aacatgttca aaattatatt atcagtaatg aaaaagaaaa ctgtgtaatg gcttgttttg
    35401 atttatgtag actcaaactt ataaatgata tatatggtta tgagttaggg gatgaagtgt
    35461 taaataatat tttaagtaac ttaaaaaatt attttggaaa agaagctatt tatggaaagt
    35521 taaaaagtga tgtttttgta ttaataataa agcttgaaaa tagggaacag aagattcctt
    35581 atttagtaaa tcttattaag aataaaattg tgatactaag tcagattgac agttttaaaa
    35641 tggatataaa tattgaagct tctattggaa tttataaatt taataataat gaaattgata
    35701 taaaaaaagt tatagataat gctgatatgg caaggcttaa atcaaaagga ctaaagcaca
    35761 tagagtatgt agaatttgat aatgctatgg aagaagaaat acaatcaatt atgaaaatag
    35821 agcgagattt attcttggct attaaaaata aagagtttgt aattcactat caacctaaag
    35881 ttgattcaag tacaggtaac attataggct cagaggcatt aataagatgg ttgcacccat
    35941 cattaggcat ggttggacca aataagttta tacctatagc tgaaaaaaat ggtctgataa
    36001 acaatattgg tagatggcta attcaagaag tttttattac cattaacaag tggatttcag
    36061 aaggtataaa tgtcttacca gtctcaataa atctttctag agtagaacta tataaaaatg
    36121 atttagttga tttttttaaa ttgatgttta atacatataa tattccaaaa gaacttatag
    36181 aattagaaat tacagaaacg acagcactaa gagatgtaaa atttataagt gaaaggcttt
    36241 atgagattaa atctttagga atgaagatat cattagatga ttttggagta ggtaattcaa
    36301 attttatcaa ccttaagggg ataccactag atattataaa aattgatagg tcacttatat
    36361 tggatatagt tacaaataca aaaacaaagt ttatggtgaa agcaattgtt aacctttcac
    36421 atgatttaaa cgtaactgtt atatgtgaag gggtagagga tatgcatcag gtcaaagtct
    36481 taagtgaact gggatgtaat ttcatacaag gttatgtatt ttttaaacct ttggatgaga
    36541 tgaattataa aaaacttctt actgacggaa gttatataaa tctgaaagat actcttttag
    36601 ataaatgcat gacagttgag gaggagtaag gatgatttca gaagatgtag attattcaat
    36661 aagaatcata agagctatat ttaataatgg agaagataaa ccaatagatg ctaaaatgat
    36721 attaaaaagt gaagatatac caatactaac actatacaga ctgcttagaa agctttgtgc
    36781 aaacaatatt cttactttta acaaagaaga tggcaagaca tacatgttaa atgtgtcatt
    36841 ggatacaata agtctaagaa ctattgtaga agtaattgat ggaaaaatat atataaataa
    36901 atgtacgaga tatgtatcta attgcagtaa ttgcttaaaa ggttgtaaag taaatcgtga
    36961 attgctagaa atagaaaaag aaatttataa acttttatcg agaaaatcta taagacaaat
    37021 actagaataa aaaattttca gctatgataa taattggagg ttttcggtta tggatgatat
    37081 atctcaagat aattttctac tgtctaaaga gtatgagaat agcttagatg tagatactaa
    37141 aaaagcaagt ggaatatatt atactcctaa aataattgta gattatattg taaaaaaaac
    37201 tttaaaaaat cacgatataa ttaaaaatcc atatccacga atacttgata tttcctgtgg
    37261 gtgtggaaat tttcttttag aagtatatga tattttatat gacttatttg aggaaaatat
    37321 atatgaattg aaaaagaagt atgatgaaaa ttattggact gttgataaca tacaccgtca
    37381 tatattaaac tattgtatat atggtgctga tattgatgaa aaagctataa gtatattaaa
    37441 agatagctta acaaataaaa aggtagtaaa tgatttagat gaatctgata taaagactaa
    37501 tctattttgt tgtgatagtc ttaaaaagaa atggcgatat aagtttgatt acatagtggg
    37561 taatccaccc tatattggtc ataaaaaact tgaaaagaaa tataaaaaat ttctcctaga
    37621 aaaatatagt gaagtttata aggataaagc tgacttatat ttttgttttt ataaaaagat
    37681 tatagatatt ttaaagcaag gagggattgg cagtgttata actccaagat attttttaga
    37741 aagtctatca ggtaaagatt taagagaata tattaaatca aatgtcaatg ttcaagaaat
    37801 agtggatttt ttaggtgcaa atatatttaa aaatataggg gtatctagtt gtattctaac
    37861 ttttgataag aaaaaaacaa aagagacata tatagatgta tttaaaatca aaaatgagga
    37921 tatatgtata aataaatttg aaacattgga agaacttcta aagagtagca aatttgaaca
    37981 ttttaatata aatcagagat tgctatctga cgaatggata cttgtaaata aagatgatga
    38041 aactttttat aataagatac aagaaaaatg taaatatagc ttggaagata tagcaataag
    38101 ttttcaagga ataattacag ggtgtgataa agcgtttatt ttaagtaaag atgatgtaaa
    38161 gttgaacctt gtagatgata aatttttaaa atgttggata aaaagtaaga atataaataa
    38221 atatatagta gataaaagtg aatataggct aatatactca aatgatatag ataatgagaa
    38281 tacaaataaa aggatactag atgaaattat agggctatat aaaacaaaat tagaaaacag
    38341 aagagaatgt aaaagtggaa taaggaaatg gtatgaactt caatggggta gagaaaagct
    38401 tttctttgaa agaaaaaaga taatgtatcc ttataaatca aatgaaaata gatttgctat
    38461 agattatgat aacaattttt caagtgcaga tgtatattct ttttttataa aagaagagta
    38521 tttagataaa ttttcatatg aatatctagt tggaatttta aattccagtg tttatgataa
    38581 atactttaaa ataactgcta aaaaaatgag taaaaatata tatgattact atcctaataa
    38641 ggttatgaag ataaggattt ttagggataa taattatgaa gagatagaga atttatcaaa
    38701 gcaaataata tcaattttat taaataagtc tatagataaa ggaaaagtag aaaaattgca
    38761 gataaaaatg gataacttga taatggattc tttaggtata taagcagttg taagtattaa
    38821 aaaattataa tcttttaatt gtttatttaa atttagaaat aaaaagttag ccatataaaa
    38881 aatattaaaa atatatactt ttcaatattt ttttgataaa ataagaatga atttgtgcaa
    38941 ttttattttt ctccaataac taaaaatagt tttttgaatt aatatttgct taagaataaa
    39001 aatcagaaac gtttttgata tagtaggtga taatatgaaa ggattagttt tagaaggtgg
    39061 aggaacaaaa ggagcctacc aaataggtgc atataaagct ttgagagagc ttggtataga
    39121 gtttcaagga gtaactggca catcaattgg tgctttaaat ggagcatata tagttcaaaa
    39181 tgatattgaa gtaatggaag atatttggtt aaattatgac tatactcatt ttatgaatat
    39241 tgatagagaa acctatgaga ggtttaaaaa tgtagatttc actactaaaa atctcaatgc
    39301 agtgtttgag cttataaata aagctagaaa aaatgaaggt atagatataa gcccattaag
    39361 acaactaatg gagacaacat taaatgaaga cataataagg aaatcaaaaa aagactttgg
    39421 acttgttacg gtctggtggg ataaaaaaat taatccatat ccattgtata tcgaagatat
    39481 acctaaagga agattgattg attatttaat tgctagttcc agtttgccta tttttcaaac
    39541 gaacatgatg gatgataagt tgtatcttga tggaatgttt tgtgataaca tgccaatagg
    39601 actcttggaa gacaaaggtt atgaagatgt tgttgtaatt aggttgattg atgattttat
    39661 tgggaaaatg aatctaaatc gacatcaaaa tataaatata aaaactataa taccatcaga
    39721 atatctagga ggttctctta ataaagatag agataatgta gaaaaaaaca tccgactagg
    39781 ttacttagat actatgaaag catatgaaag atgcactgga attaagtatt attttgatgt
    39841 agagtataaa tataatgaag aatattgttt tgataaattt agaagtatga gcaatgaaac
    39901 aatacaatat atctgtaatt tattgaatat aaaaagagat gcttcactta gaactgttat
    39961 ggaaagtgta ataccaaagc ttggtgaggt gcttggattg ccaaaggatt tttcatataa
    40021 agatttgttt tactgtatat atgaaaagaa acttgaagaa aataatataa acaggataaa
    40081 attatatgat tttaacaagg ttatagatgt tgtaaataca aatattgatt ctaatagaaa
    40141 tttagcttct aattttgaag ttagacctaa aattagtatt aaaaagaaca aaaacacaaa
    40201 attattgaca aattgtatta taaaagacat aaaaaatcaa agttaaataa aaaacaaaaa
    40261 aaaatttgta attatactcg aaaaaagtgt atattagtag tataatattt ttgtagcact
    40321 agtgggaaca aaaaatgacc ataggacaaa aaagtaccac ttagtaccat taaagtaaaa
    40381 aacaggaaaa caattttaaa aaatataaaa tgtaaagttt ataggaggat ttaaaaaaat
    40441 ggaaaaagta gttagtatca aaaatgcaag tggattacat gctagaccag caggaatgtt
    40501 tgttaagaag gcagctgaat ttaaatcaac agtagaggtt gtagcaaaag acaaaactgt
    40561 aaatgcaaaa tcaataatgg gaataatgag tttaggttta gctcaaggag aagaattaaa
    40621 gttagttgta aatggagaag atgaagaagt agctttagct gcaatggttg aattagttga
    40681 aagtggattt ggagaataga tataataatt tttaaaaatt tgatatttag aatctaatat
    40741 tacttaaagt aaagtaacag agaagtatta aacatataca gaccaacatt tgtagatatt
    40801 taatttcttt gttactttca tgtttattta atcagaagat taagactatt gttaattggg
    40861 tataaaaata taaatatttt agaaaatgaa ataagatatt tttaatcata aattcagagt
    40921 aaaaatacag taacaaatag tttataaaat tttataaaaa attataagta aataaaacta
    40981 taaaaatgta aattatttat ataaatttat aaagtttatg tgctagatga tattttttag
    41041 gaggtagggt tatggcttac aaaggaatag gtgcttctcc tggtgttgct ttagggaaag
    41101 cgttagtagt tgaacatagt gaattagtaa ttgaaaaaaa atctatagat aatgttgaag
    41161 ctgaaattgc taaattagaa gatgcagttg cagtttctaa agaagaatta gtaaaagtta
    41221 aggaaaaggc ttctgaagaa ttaggagcag aggaagcaga aatatttgaa gcacatttat
    41281 tagttttaga agacccagag ttaattggtt ctgcaataga taaaattaaa actgaaagtg
    41341 taaatgcaga gtatgcttta aatgaaataa aagagatgtt tgttagcatg tttgagtcta
    41401 tggacaatga gtacatgaaa gaaagagcgg cagatataaa agatgttaca aatagaatac
    41461 ttagacatat attaggaatt aaagttgttg atttatctgc tttaagcgaa gaagttgtat
    41521 taatagcaca tgatttaact ccatcagaca cagcaactat gaataaaaaa atggttttag
    41581 gatttttaac tgatataggt ggaagaactt ctcatactgc tatcatgtct agaactttag
    41641 aaatagctgc aatcgttgga ttaaatgata taacttcaaa agttaaggat ggagattttg
    41701 tggttttcaa tggagacaca ggtgaagtaa tcgtgaatcc tgatgaagag actataaata
    41761 aatatactga attaaaagct aagtatgaag atgagagaaa agcattacag ctattaaaag
    41821 gaaaaccatc tgtaacttta gatggaaaac atgtggaatt agctggtaac ataggaacac
    41881 ctaacgatat agaaggtcta ataaagaatg atgctgaagg tgttggtctt tatagaacag
    41941 aatttttata catggataga gattctttcc caacagaaga aatacaatat gaagcataca
    42001 aagctgtatt agaaggaatg gatggaaagc ctatagttat aagaacattg gatataggtg
    42061 gagataaaga attaagttat ttaagtatgg aacctgaaat gaatccattc ttaggttaca
    42121 gagcaataag actttgccta gatagaaaag atatatttaa gactcaattg agagctttat
    42181 atagagctag tgttcatgga agattaagaa tcatgttccc aatgatttca tctttagaag
    42241 agttgttaca agctaaagaa gttgtaaaag aagttttagc agaacttgat tctgaaggtg
    42301 tggcttatgc taaagatgta gaaattggta tgatgataga agttccatct gctgctgtga
    42361 tatctgatgt attggctaaa cacgtagatt tcttctctat aggaactaat gatttaattc
    42421 aatacacttg tgcagttgat agaatgaatc aaaagataag ttatctttac aatcaattta
    42481 atccagctgt tttaagactt ataaagactg ttatagacaa tgcacataaa gaaggcaaat
    42541 gggcaggtat gtgtggagaa tctgctggag accaaaaaat gataccaata cttttaggta
    42601 tgggattaga cgagttctct atgtctccaa tatcaatact tcctgctaga aagttaataa
    42661 cttcagttaa agagtcagat atgaaaaaat tagctgatga tgtacttaat atgggtactg
    42721 ctgaagaaat aaaaagctat atagaaaaga cttttaatat ataattaatg ttatatagtt
    42781 actaaaattc atttttctaa ataacaaaat tatattttac gaataaaaaa actatagtat
    42841 atcatatata ctatagtttt tttgttatat aaattacgta tcaaaatttg taaaatgaat
    42901 agatataatt actaaatatg tgatagtatt ggctataata ggatataaaa aataatattg
    42961 taataaaaag tttatattta gtaatgaaaa tttaacgttt tacttgaaat tatgtgtttt
    43021 gtaatgtatt attaaggttc taataggaac attttcatca atttttctat agtgggggta
    43081 ggaattatga ggtacaaaaa aagaaatata gataagtcaa gtgaactttc atttcaatct
    43141 ctagcaaaat attttataac tttctatata gtaattatat taattattct ttctatgttt
    43201 tgtataaata caatatgggt tatgaaaaaa gataatcaag atttattatc tacaacatca
    43261 aatcgtattg aagatagggt aggagaaaca attaagctat tgaactcttt gagtaaagat
    43321 aattacataa tagataatag tgtgaatggc atagataaaa gtaaagaact ttcaatgtat
    43381 agtgatgaat ttgggtatat gatgatatgt tttgttgata agaatataat tgtatgggat
    43441 gaagaaggtg gtaatattag tctagctggt cgtgattata tgcagaaact ttttgcaaca
    43501 aaaaaatatc aagttacaga tagttttgca gcaggggctg atggaaaaac tttaaactac
    43561 actattgcat cacctataat aaagaatgga aatgtagatg gttgtgtatt tgcagcaatt
    43621 tactttgatg agataaagga tatactcaaa caaggaaaag gtcaacagca acagaatttc
    43681 atattatttg gaagtgaaaa tcaaataatg aatttaacaa gtgatgaaac tgcatatgga
    43741 gagaagtata tgaagttatc gcagaaaaca aaatatcttg gaaccaatgc aaaaaaagta
    43801 gaaaaggata tgtttaataa taaatcaggt gattattggg cttttgaaaa tggaaaatta
    43861 tactttatgt cctataaacc aattaagaac acaaattgga gtttattttg taaagttaat
    43921 ttcttagata tttttgcatt aaatttaatt cctatgggag ctattctatc tgttataact
    43981 ttagtattta ttattttgat ttgtatggag aaaagcttca tgaaaaaacg aatggaagtt
    44041 attgatatgc ttttaggttc tgttcaagaa ttagaaaaac gtatatatca aacagaaaga
    44101 cctagtgaag tagactttaa agaaattatt cagctcacaa gtaaaggtct gactgatgga
    44161 ttaactggtg ttgtaacacg tactgtattt tttgaccaaa tttataatcg tgttgaaatg
    44221 gaggaaaatg ataaattatc tgtaatttca tttgttgatt tagatgattt gaaatgtatt
    44281 aacgacttat atggacatga aattggggat atggttttga aaaatgttgg atatgtactt
    44341 cgtgaatatg agataaaata taatggttta attgggcgct atggtggaaa tgaatttgtt
    44401 atgttgttat ctggttttac atcgagagaa gaggtggagg atttattgga tgagattgct
    44461 attcgcttac atactgaagt actaacagat gatggtatca ttcaaactca ttgtagtgtt
    44521 ggagctgtag tatgtagtgt aaaagacaat aaagatatag ataatttatt aaaacaggct
    44581 gatgaagctt tatactatgt taaacgtaat ggaaaaggta attatcattt agtttaatgt
    44641 atgtggaagg agtttatatc atatgaaaaa tgtatctaaa aaattttttg tatgtactat
    44701 tattgtatta ataacatttt tatgttttag taaatttgct atttatgttt ttgacaaaca
    44761 agaaaagaaa gaaacaaaag tagtagaaaa catgttaaat gtctacaaga ataacattat
    44821 tttaaatctg actgaaaaat ttaattatag caaagacttg acatcagttt tagtttcaaa
    44881 caattattct atagataaat taaaacctat tgcagatgaa attcttaaaa acaattcttg
    44941 catatatatt tcagttgtag aaaaatataa tgtagctgca tttttttcta attctgtcaa
    45001 aaaagatatt atcaatactc caatacagga actgaattat tcttattcat tagcaaattc
    45061 tatcaaagga ttagtcgtag aaggtccttc taaagaccag ttttcaaatg gagatgtgtt
    45121 tttaattact aatcctattt ataaaaatgg agagtactgg ggagaaatta cagtagcttt
    45181 agatgccaaa aaagttgtag attcttttaa cttaaataaa ttaaaagaat ctggatttga
    45241 gtatgaactt tggcgtgtac acctagataa tggttcaaaa tctacaatag aaatttctac
    45301 taaagatttt aattttccaa atcacatgaa attaagttta aacttccgac tgtttggact
    45361 cttagcattg tgtacaaaaa tggatggaat aataagaata tagattttat tgtatttgtt
    45421 atattattaa ttatttccat attaataggt gtgatgacat ttatttacat tgaaaagaag
    45481 tcgattagta aggaattaaa tcaacagagt cttaaaaatt tagaaactgg tattttgaat
    45541 agagaaggtt ttttaattaa gttacaagag catctgaata gaaaaaataa tgaaatagtg
    45601 ttgctgtata tatgtattac taattatagt aaatttgctc cagttatgag ctttgaaaaa
    45661 agacaagatt atcttacaca tatagtaaaa aatctagata attacataaa aagttctcat
    45721 tttattgctc gtataagtga ggaaggtttt gttctagctt tagaagaaaa ttgtgataaa
    45781 aatgaattgc ttaacattga aaaagggatt tccttagagc ttttacgaaa aattaaagta
    45841 gaaaataaac aagtattttt aacgattggt tatggttcat ctaggtgtgt tgatgataga
    45901 aaagatgcag aatctctgtt actttcagct attgaagatt atgagagaag atttccagca
    45961 atgtctccta ttcatgattt tactaaaaag tgtgaagata tgcttgatga aaagaaacag
    46021 attgtatttg gtgaatatcc agatttagaa ataaacaagt tgtctaaagt aatatacaaa
    46081 tattataaaa aagtacagcg tattatgtat aaagattata atattgatat tggaaataga
    46141 cgagggtata tgcgtgatgt cgaagtatta attgattata attctgagag aatgttatac
    46201 ttatttttaa tagacatatg caagtttgga aaatttaatg aactgttttc tattgaaata
    46261 ggagatgtta ttttaaaaga agttagtaac aaattaaaaa caattttttc taattatcta
    46321 tatcgtatta atggagatgt atttttaggc atttcaatag ataaagaatc ttacttagat
    46381 actttacata aggttaatga agtatttaat agttctttaa gtgtagaaga tgtacttttt
    46441 gatgtaaaat gtaatattgg tatttgtcaa tatccatatc atggtgaaaa tccatatgac
    46501 cttctggaaa aggtacaaat tgcattggag tatgcaaaaa aggatgtcaa aagtaatgtt
    46561 aaagtttatg ataaggaatt gacagaagag atttaccatg aaaataatat tattaaggat
    46621 ttaaaaaaag gtctggaaga acaaacacta gaagtttggt atcagccaat ttttaatgtt
    46681 agtaaaaact gttatataaa agctgaggca ctaattagat tgagaaataa agagggcggt
    46741 tattattctg cctatgaagt tattacttat gcagaaaagc atggacttat taaggatgta
    46801 ggtctatatg tactaaaaaa ggcttgtgat gtaactacaa aaataaaaga taaaaatata
    46861 gattttgaac aaatgcaatt aaatttatct gttcagcaga ttgtacataa gcagtgtgca
    46921 aatgacatat tatcatgtat tgagaattgt ggtttagata aaaagtatat ttgtgttgaa
    46981 gttacagaaa cagtacttat ggaaactttt gaaattgtaa atgttactct tgataaacta
    47041 aaaaaagaag gcattagcat agctttagat gagtttggtt ctggatttag tagtataaat
    47101 tatctggcaa atttacctat tgaaaattta aaaatagata aggaattagt agaacaaatt
    47161 acctattcta aaaaacaatt tgaattatta aaaactatag ttcaaattgc taagattaat
    47221 ggcatggata ttgtagcaga aggtgttgaa acaaaagaaa ctctggattt agttgtaact
    47281 tcaggtgtga atttgattca aggtcattat ttttcagaac ctttaagtga agataaattt
    47341 attgaactta tgattgaaga ataaaggtta ataaaataaa gatttaaggt attgaaaaat
    47401 aattaaaagt atttaataat agaattaggg aagaataagt ttataattaa aaataattga
    47461 ttagtagtta ataaaataaa tgtgatatcc aaataaatcc taaatctaat ttgagtttta
    47521 atatagatag tctaaagttt gattattaaa gatttaattg taagttgtta cagttgatga
    47581 tattgattag agattaaagt ttagagtaga aagttacctt aaatttaaaa atgcaagata
    47641 acccaatcta aaaattataa tcactcaata ggtttaagga tttatttgtt tattataaat
    47701 aggagggtgt ctcaaaatga actttttagt ttatgaggca ctctctttta tatagaatta
    47761 aatatatttt attatttcaa caatgaaaaa gaagcttatc tctattttga gacagcctct
    47821 ttgtatacta ttattaattt aatcaataac ataatttaaa attatattat tagttaagat
    47881 ttcctgcttt attagtaaat aattctttaa tagcattgtt tctggaaact aaatcgttat
    47941 cagagttgtt tgtttttttc ataatcactg aataacgttt tttatttata aaaaatatta
    48001 aaatcttatc atcatcaaaa ttgtattctt tatatctgtc aatagactca taacctagat
    48061 ttagaatgtt tttgtctttt atactatcta catctaaaat atatgatggg tcagccttta
    48121 gtaatatatt aattaaacat ttttcttcac cagcacagaa taactccatc ttacttgata
    48181 tagatttaga ttgctctgaa gttatttttg caggaataag gttgtcatta tcatctctta
    48241 gaagataacc atgtgtgtct tgttgatata ctaaattaac ctttttctta ggaacactaa
    48301 tcattttatc taaatgtaca taatgatgat tttcaacaaa accttcattt aatatttcaa
    48361 caaagttatt aattttacct aggcaaaaag attctataga ttctttacag aatttatttg
    48421 taaatggtat tatgtttacg ttttcctcgt ctgtattcca tgctatagca taatccaacg
    48481 aatatacttc ttcctctata tctgcaaaat tatattgtac tatgtttcct ttcaaaatta
    48541 ctcgacctcc atcttataat atatttaata tactttataa aacttatatt atatttaaat
    48601 aatatcataa attgaataaa tatgatatag taaataagaa aaaatttgaa aaaaatcact
    48661 ataaatgagt aataaatata aatagtatat actaatggga tggaaaatgt ccactattaa
    48721 ctttattacc ccacatatat aagataaaat tattaatata aaatataatc tatcgacaat
    48781 gaatagactt ttaaataaac ttaatataaa attaattaaa taagtgctta aaaacgattt
    48841 actttaatga tagaatcata ttaaaggagg ataattttat ggatataaag aataaaatta
    48901 aatctatatt tttaccagaa aaaaatgact atttagatga tgaagaattt gagtatgata
    48961 tagaaaataa tgaagaagat ttaaaggaag ataacaaagt acatttaaat gatttaagca
    49021 gagtaaaata tgattacaga gagttaaaag acatagaaaa ccaaacagaa gagatgtgtc
    49081 tgctagcagt aaagcaggat ggtactataa ttgagtttgt aaaggacaag acttataaag
    49141 tatgtatgga agcagtaaaa cagacatata aatctcttaa gtatataaca aatcaaaatg
    49201 aggatatttg tatagaagca gtaaaacaga actacagagc tttgtactac ataaataata
    49261 agacagaaaa tgtactaatt gaggctataa aaaatgcatc aacttatgat gtcatggaag
    49321 tatttaaatt tgtggaagag caaacagaag atgtatgtct agcatttata gaaagggcat
    49381 ctaaaaatga tgttgcagag atattaaaag gaataaaaga gcaaactcca gccatatgtt
    49441 tagaagctgt aaaaaaagat ggaaaatctt tagcttatgt aaaggaacaa agtaatagta
    49501 tatgtttaga agctgtaaaa gaaaactaca gtgcactatc ttgtgtaaaa gagcaaactg
    49561 aagaaatatg tatagaagca gtaaaacaga atgactttgc attgtattat gtaaatgaac
    49621 agacagaaaa aatatgtatg gaagcagtaa aaagaagtta tatggctcta cagtatgtaa
    49681 ataagcaaac agaagagatt tgtttggaag cagtaagaat tgatggaaga gcattacagt
    49741 acgtaaaaga gcaaacagaa gaaatttgct tggagtcagt tagacaaaat ggaaaagtac
    49801 tgcaatatgt aaaaaaacag actgaaaata tatgtataga agcagtaaga ggttcatttg
    49861 aagaacttga aataaaagaa atattaagtt gtgtaaagat accaacagaa agaatatttg
    49921 tagaagcagt aaagcaaaat ggaaaaattc ttaaatatgt agaaaatcag acagaattaa
    49981 tatgtttaga ggcagtaaga gaaaactata atgctttagc ttatgtaaag gaacaaacag
    50041 aaaagatttg tttagaagca gttaatcaaa gttatgaagc gcttaaatat gtgaaagaac
    50101 aaacagaaga agtttgtcta aaagcagtaa aacaagatta tagaatgttg aaatatgtaa
    50161 ataatcaaac agaaaaaata tgtttagaag cagtaaagca aaattataga gctttagaat
    50221 ttgttgataa tcaaacagaa aaagtttgtc ttgaagcagt aaaacagaat agaaaagcac
    50281 tacagtatgt aaaacaaaaa caaagttaaa aggctaaaat atatagaaaa catatgcaaa
    50341 taaataaaat ttgatatttt gtaataaata aaatgggtat ctcaaaagga actttttagt
    50401 ttgtgaggta ctctttttat atgaaatgaa atatattttt agccttttaa caatggggaa
    50461 aaggtttatt tctattttga catagctttt tatgcatata aaggttgata aaattgtttt
    50521 attataattg ttttgttata taaataataa gaagaaaatt atataggtct ttttttgacc
    50581 agttttacat ttttaacaac tagttttgta aagtatattg aattttctca aaaaagaatg
    50641 tactctatat atgtaaaatt tttttggagg taaaaatgtt taaaagatat gctgaaaaaa
    50701 tgacatctgt tttaatttgt aataatatga tagataataa tgaatctaaa gtctattctt
    50761 atggatttga aatattaata gctttcatag ttaatataac caccatgctg tttataggtt
    50821 ttttatttgg taaatttaca tatgtattat tttttttaat gtgttattgt ccaataagac
    50881 aattttcagg agggtatcat gcagacaatt attttagatg cttattaacc tttattttta
    50941 taattttatc tacaatctta attatagaaa atataaatat agacttattt aaaaatatta
    51001 ttatgattat tgcaagtgtt agttgggttg gaatttgtgt tctgtgccca atagaacata
    51061 ggagtaaccc tataagtgat agggaaaaat tggtttataa gaaaactgct atatttatat
    51121 ctacagtagt gttattgata acaattttaa gtctttcttt gagtatattt gtagattatt
    51181 tcacatatag cgcatttgcc atgttttgga tttttgtgat gttagtatta ggtaagttaa
    51241 aagctaaagt ataagtaaaa tatgtatgag ggagagttaa gttatgaaaa agtttattgt
    51301 aagatttatg aagtttgcta gctcattggc acttagcact gctattttgt cagctaatag
    51361 tacctgtcct tggattattc atcagcctaa agtacccaaa gaaatcagca atctaaagaa
    51421 gacaaattaa atacaagcac ttatttatac aaaattatca ggaaaaaaga aattattata
    51481 ttttaataag attaaaacaa tataaaatca gatacaaaat ttattttatt tattttatag
    51541 gagcctaata cctatttggt aatatattag tgcgccaatt tagggggata tagtgtattt
    51601 aatgaaatga cttacggaga gtaagtcatt tttgtattgt atgtatttta tgtaaactta
    51661 tgatataatg aagggtaaag tttaattaaa ataataaaaa actttagtat agatagtaat
    51721 ttaggaggta gggtatgagt atgatacata aattttctat gaatggatat aatatcgttt
    51781 tagatgtgaa tggtggagct gttcatgtgt tagatgatgt tgcatacgat ttgttagatt
    51841 tttataaaga aaaaagtaaa gaagaaatat tagagatatt aaaatcaaaa tatcaagaag
    51901 aaaaaataaa tgaagcatat gaagaaatat taaatttgga aaaagagggt cttttatata
    51961 cagaagatac atatcaatat catccaagct ttgtacatag agagcctgta gtaaaagctt
    52021 tatgtttaaa tgtagctcat gattgtaact taaaatgtaa atactgtttt gcagctcaag
    52081 gtgattttgg aggagaaaaa gaacttatga gttttgaagt tggtaaggca gcaattgact
    52141 atttgattgc taattcagga agtagaaaga acctagagat agatttcttt ggtggagagc
    52201 ctttgatgaa ctttgaagtt gtaaaacaac tggttgacta tggaagaagt gtagaaaaag
    52261 attataataa aaatataaga tttacaataa ctacaaatgg tgtactgcta aatgatgaga
    52321 ttatagatta tataaatgaa aatatgcata atgtagtttt aagtttagat ggaagaaaag
    52381 aagttaatga taatatgaga ccaactttaa atgataaagg aagttatgat attacattac
    52441 cacgatttaa gaaacttgtg gaaaaaagag caaaagataa gtattattat ataagaggta
    52501 cttttacaag agataattta gatttttcaa aagatgttat gcattttgca gatttaggat
    52561 ttaaattaac ctctgtagag ccagtcgttg gagatgagag taatccatat gcacttagag
    52621 aagaagattt acctaagata tttgaagagt acgaaaaatt tgctgtagag tatgcagata
    52681 gacaattaca aggagatgga tttaaatttt tccattttat gatagaccta aatcaaggtc
    52741 catgtgtaat aaagagaata actggatgtg gagctggaaa tgagtatctt tctgtaactc
    52801 caaatggaga tatctatcca tgtcatcaat ttgttggaaa tgaagaattt aaaatggcaa
    52861 atatatttga tgaagaaata gtacttccag aaaatttaaa aaatatgttt agagaagctc
    52921 atgtatatac taaagaagag tgtaaacaat gttggaataa gttttactgt tcaggtggat
    52981 gtcatgcaaa tgcgataaac tttaataatg acatatcaaa accatatgaa ttaggctgtg
    53041 aaatgcaaag aaaacgtaca gagtgctcta taatgataca agctaagtta atgttagaag
    53101 gagcaaccaa ctaaatttat attttaaagg agttgtttat atatgattag agattattta
    53161 gaagataaac ctttaattga cgaaagtgta tttgtggcaa aatcagcaga tgtaattgga
    53221 aatgttaaaa taggcaaaga ttcaagtata tggtacaatg cagtagttag gggtgatgaa
    53281 ggaccaataa ctattggaga aaacactaat atacaagatt gttctatagt gcatggagat
    53341 acagaaacta taattggtaa caatgtaaca gttgggcata ggtctatagt tcatggttgt
    53401 aaaattagtg ataatgtgtt aattggtatg ggttcaataa tattggataa tgctgaaata
    53461 ggagaatata ctctgatagg agcaggtaca ctaattacat ctaataagaa gtttccacca
    53521 ggtgttttga taatgggttc tcctggtaag gttgttagag agcttacaga agaagataaa
    53581 aaatatattg atgaatctta tgaatggtat ttagaggcag cacaaaatca aaaatattag
    53641 tttaaagagt ggttgtttca aaacatattt aaatctgttt tgaggcaacc actaatttat
    53701 tttattagat tttgttgata ttttagtttt caaaaagtat ttgattaaac cagatataaa
    53761 atgtcaaaaa taaaaattaa ctgagttaaa taattttaat aaaattggta gtatatgtga
    53821 taaaattaaa tattaaagag gatataggat attagaatat caattggtga aataatgtca
    53881 tatacgataa attaaggtgt aagtttttgg gtatacctat cttaggagtg aaaagatttg
    53941 agaataagtt atagaaattt aaagcgatat agagaaattg gatatgtttt aataaagtat
    54001 ggttttagtt ttattgtaga aagactaaat atagaaggaa ttgcctataa aataccacta
    54061 tttgacccac cagaagaaat aaaaaatatg acaactggtg agagaatgaa aagagtttta
    54121 gaagaactag gacctacata tataaaaata ggacagatat tgagtacaag aaaagacttg
    54181 ttagaccagg atataattga tgaaatatca aaactcagag atgatgtaga gaaatttgat
    54241 tcaaatatag ctattgatat atttaaagaa gaagtgggtt taagtataga agaaatattc
    54301 ttagaattta aagaagaacc aatagcagca gcttcaattg gtcaagttta tgaaggtgta
    54361 cttaaaacgg gagaagaagt aatcgtaaaa attcaaagac caaatataga gaaaataata
    54421 aaatctgatt tagagattct tagaactatt gcaaatactt taaaagattt aaaaaaggat
    54481 tttaatttag atttagtaca gatgattgaa gaatttcaaa ctcaattaat gagggaactt
    54541 gattatacat ttgaagctat aaatgcaact aaattctcta ggatatttaa aaatagtgat
    54601 gaagtatata tacctaaagt atactcagaa tataatacta agaaaatttt agtaatggag
    54661 aaagttaatg gtacaaagtt aagtgatgta gaaaaaataa ggagactagg ttataacaca
    54721 aaaactattg ttgaaatagg cgttaggtca ttttttacac aggtattatc tcatggattt
    54781 tttcatgcag acccacatcc aggtaatata ttcgtagttg ctaaaaataa gatagcatat
    54841 atagattttg gaatgattgg aattattgat aataaaactt taaaccaatt aaatgaaatt
    54901 gcattagcag gtgtagaaaa gaatgttgac aagataatat atctattgat agaaatggat
    54961 gcattaaatg gagaggctga tattaaggga cttagacagg atttacttta tctaatacat
    55021 tattactatg atatttctat agaaaaaata aatgtaacag atatattaaa tgaactattt
    55081 aggtttttta gacagtataa aatagtcatg cctgcacaat ttgtaactct tgcaaagaca
    55141 gttataacat tagaaggaac aagtagaact ttaaacacag atttttcttt tggttctatg
    55201 ggaaaagagt ttatgaaaca tcattataag agtaaattta accctaaaaa tgttgtttta
    55261 agttcaagac aaaatgtaga agaaatatta ctggacataa aaactattcc aaagcaatta
    55321 aaagcaattt taaaaaatat agaaagaaat aatataaaaa tgcaaattga agatgttaaa
    55381 atgacgaggt tagaaaattg tataatagag ctaacatctc aaatatcttt gagtttagtg
    55441 ttggcatcta ttatagtagg ttcttctctt ataattgcat ctccaaatat agaaaataat
    55501 atatggataa aatttactgc aatagcgggt ttctttatat cctttataat aggcctttgc
    55561 ttagttataa gaagtattag gtcaaaatac aaaaaagatt agggggaatt aaatttgaaa
    55621 aaatggatat tgaagtataa aggtaagata gaggaaagtg aatttagcaa aaaacttaat
    55681 atttccccgg aaatctgcca aattttaaaa aatagaggga tatgtactga aaaagattca
    55741 gaaatattta tgaatccatc tttagattat ttaagagacc cttttttaat gaaagatatg
    55801 caaaaagctg ttgatagaat aaagttagca gttgagaaga acgaaaaaat ttggatttac
    55861 ggagattatg atgttgatgg tgtatcatct acatctatct tgtgcttata ttttaagagt
    55921 ataggttaca atgttgatta ctatattcct aatagattag aagaagggta tggtataaat
    55981 gaagatgcta ttaagcttat aagctctagg ggatgtgact tgattataag tgttgactgt
    56041 ggaattacat cagtgtctga ggtcaataca gcgaatgatt tgggcataga tgttataatt
    56101 acagaccatc atgaatgtca aagtgaaatt ccatcagcct ttgcagtaat aaatccaaaa
    56161 caagaagatt gtaattatcc atttgattca ctatgtggat gtggtgtagc atttaaaatg
    56221 attcaagcct tgactccaaa agaagaattt aaaactagta tgtataatta tttggaaata
    56281 gtaacactag caactatttg tgatattgtt ccacttatag atgaaaatag aataattgta
    56341 aaaaatggtt taaaatcaat gaaagaaggc aaaaatattg gattaaggga gcttataaaa
    56401 gtttgtggtg tagaaagtga taagataggt tcttctcata taggttttgc aataggtcct
    56461 aggataaatg cttcaggtcg attgggatat tcttacttag gagtagagct atttactact
    56521 caatcacaag aagaggcagt agaaatagct agtatattgg aagaaaaaaa taatgaaaga
    56581 cagatgatag aagctaagat gtatcatgaa gctgaagaaa tgctaaagtc taatagcaga
    56641 tacaatgatg acaaagtgtt ggttttagct aaagagggtt ggcaacatgg aataatagga
    56701 attgtagcat caaagttaac tgaaaaatac tacaaaccaa caattcttct aggtatagaa
    56761 aatggggagg ctactggttc agcgaggtca ataaaaggat ttaatatatt tgaagctctc
    56821 ataaagtgca aagacttgat gactaagttt ggtggtcatg aacaagcagc agggttatcc
    56881 ttggattcag acaatgtaga aattttagca aatgaaataa ataaatttgc agattataat
    56941 ttaactgaag atgatatgat agagaatgta aatgttgagt ttgaattaca agaaaatgta
    57001 ataaatttaa atcttgtaga agaattacat aagttagaac cctttggatt aaataatcct
    57061 aatcctagat ttatagttag aaattatatt ttaaaagatt tgaaagttat aggtaagaat
    57121 caacaacatc tgaaattaag tatagaaaaa gagaaaagct atgaatgtat aggatttaat
    57181 atgagtcatt taaaatcaat gtataaagta ggagacaaag tagatgtact attccaatta
    57241 gatgaaaata actatatggg aaataggaaa gtacaatttt tacttaaaga tatacgattg
    57301 gctcgaccta aaagtgcaag taatgacaaa ctttcattga aattaatgtc aaaaataata
    57361 ccaaaagata ctcaaagcct gtataatata tctgtgtctg attttgaatt atttgatgga
    57421 aatacagata taaatatatt tgattatttt gaaaaagata cactaataat atctaattct
    57481 ataaatggat tttatagagc aatgtcagat atatcactta tagatttgga ttttaacata
    57541 aattacaata ttattgaaga tgttagcaaa aatactgata aattagagct tatattttct
    57601 cctaatattg ataaaataga cttaaaaaga tataataata ttattcttta tgattattta
    57661 tacaataaag gcgaatattc gtatatatat gagaataaaa gagaagaaag tgaaattata
    57721 aaatattata ataaaacaga cctattatat ttaaagaatg tagttagtaa tatagttcca
    57781 tcaagagatg aatttataac aatttataaa caagcactca taaaaaaaga aattgatttg
    57841 gatatggtaa atataaggga aacttttaat gtaattccat taaagttttt tacgatatta
    57901 aatgtattta gagaattaaa tttacttgac tttaatttaa attatgaaaa aaattctgta
    57961 ctcataagaa tattgccaaa accacagaaa aaattagact taaatgagag tttaatactc
    58021 aataatctaa aaaatttaga aaaacaatac aatagcagtt attaggaggc gtttcccatg
    58081 gatttaaaaa actttataag gaatattgat gatttcccaa agccaggcat agattttaaa
    58141 gatgtgacaa ctctatttaa agatggagat gcatttaaat atgcagtgga ttctatagtt
    58201 gaagaattga aagataaaga tgtagattta gtaataggac cagaagcaag aggatttttg
    58261 atgggtacac ctgtagcata tgctttagga gtaggatttg ttccaattag aaaacctgga
    58321 aagttaccag gtgaagttga gagttatgag tatggattag agtatggtac agatacttta
    58381 gagatacata aggatgcaat taaaaagggt caaaaagtag caatagtaga tgatttattg
    58441 gctactggtg gaactatgga agccgctgcc aagcttgtag aaaaattagg tggagaagta
    58501 gtttctatgc aatttttgat tgagctaaaa ttcttaaatg ggagagaaaa gttgtctaac
    58561 tatgatgtta attctcttat aaaatactag tacttttata atagttggta taacaccaac
    58621 tattttcata tatattaaaa ttttatacaa aataggtggt tatatgcatg ataaagaatt
    58681 acaagaaata attgaaaaaa taaaagttta tgcacctaat gcaaattttg aaatggttga
    58741 aaaagcctat aatcttgcaa aaaaagcgca tgaaggacaa tatagaaaat ctggggaacc
    58801 atactttatt catccattag cagttgcaaa tattttaata gagatggaat tagatattga
    58861 aactataaca gcaggtttac ttcatgatgt tgtagaagat acagaatata cctatgaaga
    58921 cataaaaaaa gaatttggca aagaagtagc ggatttggtt gatggagtaa ctaaacttgg
    58981 tcaaataaaa tatcgttcga aagaagaaac tcaatctgaa aatttaagaa aaatgttttt
    59041 ggcaatggcg aaggatataa gggttatact tataaaactt gctgatagat tgcacaacat
    59101 gagaacatta aaatacatgc ctccagaaaa agcaaagtat aaagcaaaag agacacttga
    59161 aatttatggt ggtatagctc atagattagg aatttccaag ataaagtggg aactagaaga
    59221 cagagcatta agatttatgg acccagaagg gtattatgat ttagttagta gagtatcaat
    59281 gaagagaagt caaagagagg attatattca aggaattgtt gaacttctta aagataagtt
    59341 taaagattta agtataccat gtgatgtata tggtagacca aagcattttt acagtatata
    59401 tagaaagatg caaaaaaaac ataagacttt tgaagagatt tttgatttaa cagcagtaag
    59461 gatattggtt gataatgtaa aggattgcta tgcagtactt ggtatagttc atacattatg
    59521 gagacctatt ccaggaagat ttaaagatta tatagcaatg ccaaaaccca atatgtatca
    59581 atcattacac accactgttg taggtcctga tggagaacct ttagagatac aaataagaac
    59641 tcatgagatg cataatatag ctgaaaatgg tatagcagcc cattggaaat ataaagaagg
    59701 tatctctagc aaagagtcaa aggttgaaga aaaacttcaa tggttgagac agatgatgga
    59761 gtgggaaaaa gatttaaaag acccacaaga gtttatggat gcacttaaag aagatgtatt
    59821 taatagtcaa gtttatgtat ttacgccaaa aggagacgta attgaattac cagcagaatc
    59881 aacacctata gattttgcct atagggttca tacaaatgta ggtaataaat gtgtaggagc
    59941 taaaattgat ggaagaatag ttcctattga ttataagctt caaaatggta atattgtcga
    60001 ggtacttaca tcatctaatt ctaatggacc aagtagggat tggcttaata tagtgaagac
    60061 cccaaatgca aaaagtagaa ttagacaatt tttcaagaag gaaagaagag aagaaaatgt
    60121 tgaccgtgga aatacaatat tagaaagaga atttaagaag catgatatac cacaaaaaga
    60181 ccctcttgtt gaaaaatata tggcattagt tgctaagaaa tttaatcagc caagtgttga
    60241 ggacttaatt gccactgtag gttatggtgg tataatgtca tctcaagtgg tatctaaggt
    60301 aaaagaccta tatttaaaag aggttaaaaa agctaaaaag gaacaacaga tacaagaaga
    60361 agatttaaat aaacacaata taagtgaaac agaatacagt aaaaagagaa agaaaaacgc
    60421 atcacaagga attatagtaa aagggcttga caatatctta gtaagatttg ctaagtgttg
    60481 taatcctctt ccaggagatg aaattgtagg atatattact aagggtaggg gagtagccat
    60541 acacagagct gattgcccaa atgcaaacaa taatggtgat ttcttccaaa atagattggt
    60601 ggaggtttca tggagttcag caggaaaagg taagtttgaa gcggaaattc aaataaaagc
    60661 tattgacaga agaggaattg ttaatgaaat aactcatatt gttgcaatgg ataaacttag
    60721 tttaaacgga ataaatgcaa gaaaaggtaa ggatagtatt gtaagtataa acttacttgt
    60781 agaggttaat gacacagagg aattaaaaat tctaatgaaa aaattaaaag caattcctgg
    60841 tgtagaaagt atttatagaa tgacaaatta gagttaaaat aatagggagg aaactatgag
    60901 agcagtagtg caaagagtat cttcatctaa agttacagta gatgaaaaca ctataggtca
    60961 aataaataag gggttactag tattgttagg agtgactcat gatgataaat caagtgatgt
    61021 agattatatg attgataaaa tattgaatct gagaattttt gaagatgaaa atgacaagat
    61081 gaatttatct ctaatggata taggtggaga gcttttagta gtatctcaat ttactttata
    61141 tggagattgc agaaaaggaa gaagacctgg atttagtaat gcagctagac cagaacttgc
    61201 aaataacctt tatgaagaat ttgtaaaaaa agcaaaagat aaaggtgtga cagttggtac
    61261 aggtcaattt gcagctcata tgatggtaga gttaactaat gatggtccag taacaatact
    61321 attagactca agtaaatctt tttaaggggg aaaactttaa tgattataaa aaaatttgta
    61381 gatagttatt ttggagtaaa tacttatgta ttaggtgatg aaaagactaa aaaatgtgca
    61441 gttatagacc caggtggaag tttagtagag acattaagtt ttgtaaaaga aaatgaatta
    61501 aatattgaat atattatcct tactcatggg catggagacc atataggata tgttaaggat
    61561 attaaagaaa aaactggtgc taaagtagtt gcacatgttg atgaaaaaga attattaaat
    61621 gacaaaaata aaaatctaag ttatacaatg agatgtggag cacaagagtt tgatgcagat
    61681 atctatgtaa atgataaaga caagcttgaa cttggtgaat taaaaatgac tttcttgcat
    61741 actccaggac atactcaagg atgtatgtgt ataagagttg aagatgaaat gttcacagga
    61801 gatactttgt ttgctggaag tattggtaga actgatttat atagtgggga ctttaaccaa
    61861 atggaaaaat cacttaagaa attatgcaaa tatgaagatg ctgttagagt atatcctgga
    61921 catggaccaa ccagtactct aggggttgaa aagaagacaa atccttacat gtaattttat
    61981 attagtattt aaaaaagtat aaagtattta ataactatat tagtgagggg gttcttctac
    62041 tgttaaatag aaggagttaa gttgatgttg tatgtttttt taaaaggaca tgattataag
    62101 tatgaagtag cagaacttat aaaattgttt accagtgaat ttaagtttaa agactctaat
    62161 gctaacaata atatagagtc aaagcattta ataaatagat tgatttatga gaatggtgta
    62221 ttattctcaa gtactgaata ctatgaaaat ggaaacttaa agtacgagtc aatacagaat
    62281 atagaaaata tgaatcttga atttttagat ggatttgata gcagcaaaac gattgaagaa
    62341 tttcttaata gcctagatag tgaaagtaag aggaacttta aaaagctgtg taaagaaaat
    62401 atcaaaaaaa gcatgtttgt agtgcttaaa caagtattta attcttatgt accatgggga
    62461 attttgactg gtattagacc agtcaaaatt gtccacaatt taatggataa aaagttagat
    62521 gataatagca taagaaccat tctaaaagat aattatttta taatagatga gaaaatagat
    62581 ttagctcttg aaatagctaa aagagagcga ttatttatgt atcctataga taaaaataaa
    62641 atttctcttt atgtaagtat tccattttgt ccaactagat gtgtatattg ttcatttcct
    62701 tcaaattcat taaaacaatt tggacattta aaaagagaat atgtttataa attgattgaa
    62761 gaaattaagg ggtttgccaa agttattaag gagactaaga aagaagttga aactctatat
    62821 attggtggtg gaactccaac tacacttgat gaggaagaat tggatttgct tataaattca
    62881 ttgttcaatg aattagattt aagtaaaatt aaagaattta ctgtagaagc aggtagacct
    62941 gacactatta cagaacaaaa actaagagtg ttaaaaaaac acaatgttag tagaattagt
    63001 ataaatcctc aaactatgaa tgatgatacc ttggtaaaga ttggaagaga gcatagagta
    63061 tctgatttag tagattgctt taatatggct cgtagaatgg gatttgataa tataaatatg
    63121 gatataattt taggtcttat agatgaagat ttaaatatgg taaagaatac attggaggag
    63181 ataaaaaaac tttctcccga aagccttaca gttcatacat tagccataaa gagagcatcc
    63241 aacttaaata taaatatgga taggtataaa gaacatctaa cacaatatga agaaatggta
    63301 aaaatgatag acttatcaat gaaatatgca aaagatatgg gattaaatcc atattatatg
    63361 tacagacaaa aacatatgtt gggaaattta gaaaatatag gttatgctaa agaaggatat
    63421 gagtgcattt ataatataca gattatggaa gaaaaacaaa gtaactatgc attaggtgca
    63481 ggtgctatat cgaaatttgt ttatgtagat gaagatagaa ttgaaagagt agaaaatgta
    63541 aaaaatgttg aacaatacat tgaaagagta gatgaaatga taaaaaggaa gaaagaagag
    63601 gtatataaaa atgttgacta aagctcctag aggaactaaa gacataactc caaaagaggc
    63661 ttacaaatgg cgttatgtag aaaataaatt tagagaaata tgtgctttat atggatatga
    63721 agaaatggta acacctatat ttgaacatac agaacttttc aagagaagtg ttggagatac
    63781 tacagatata gttcaaaaag aaatgtattc ttttaaagat aaaggtgata gagaaattac
    63841 cctaaagcca gaaggtacag caggtgtagt aagagcattt atagaaaata aattatatgc
    63901 agatactcaa ccaacaaaat tattttatgt gacaccttgt tttagatatg aaagaccaca
    63961 agctggtaga caaagacaat ttcaccaatt tggaatagaa gcacttggaa gtgatactcc
    64021 ttcaatggat gctgaaataa tcgcactagc tgttcaattt tttaatgaag ttggattaaa
    64081 tgatttggta gtgagtataa attcagttgg ctgtccagtt tgtagaaaag agtacaatgc
    64141 tttattaaaa gagtatcttg actcaaaagc tgatatattg tgtgatactt gcaatgagag
    64201 aagagaaaaa aatccaatga gggttataga ctgtaaaaat cctacatgta aagaaaatat
    64261 caaagatata ccatttattg cagaccattt gtgtgatgat tgtaaatctc actttgataa
    64321 acttcaagaa tacttaaagg aaatgaatat aaactttgta attgataaaa caatagttag
    64381 aggcttagat tactatagaa aaactgcttt tgaaattata tctaatgata taggagctca
    64441 aagtactgta tgtggtggag gaagatatga tggtcttgtt gaacaattag gaggaccaaa
    64501 aggtataagt ggaattgggt ttggactagg aattgaaaga cttttactta cacttgaagg
    64561 taatggaatt gaaatagaaa accctcaatc tacggatata tttatagtaa ctataggtga
    64621 agaagcaaat acaagaagct ttaaattgtt aaaagacttg agacaaaatc atataagtgc
    64681 agataaagac catatagaga gaagtgttaa agcacaattt aaatattcag ataaaataaa
    64741 ttcaaaattt acaatagtaa ttggagatga tgaacttaaa aatgacactg cgacattaaa
    64801 aaatatgaaa acatcagagc aaactactgt aaaattaagt acattagttg aagaattaaa
    64861 gcaaaagctg taaaataaga aagtatgatg ttttgtgtat tagataaata tatagcatta
    64921 aaattaaata aaatggaggt agtatcttgg aaactttaaa gggtttaaag agaactcact
    64981 actgtggaga gttgagagaa aaaaacataa atgaagaagt cgtacttatg ggatgggtac
    65041 agaaaaaaag aaatttaggt ggtcttgtat ttgttgattt aagagataca agtggattat
    65101 gtcaaatagt ttttgataca gatgtagata aagaagcttt tgaaaaagct gaaaaattag
    65161 gggctgaatt tgtaatagct gtaaaaggaa aagtatgcga aagacaatct aaaaacccca
    65221 atatgccaac tggtgatata gaaatatttg caactgaact tagactttta aacaagtcag
    65281 aaactccgcc tatttatata aaagatgatg atgatgtttc tgaagcacta agattaaaat
    65341 atagatactt agatttaaga aaaccatcta tgcaaagaaa tttaaaatta agacataaag
    65401 taatgaatat tacaagaaat tacttatcaa acaatagatt ttgcgaaata gaaacaccat
    65461 ttttaatagc tccaacacca gaaggagcaa gagattatct agtaccaagt agagttaatc
    65521 caggaaaatt ttacgcatta ccacaatcac cacaattata taaacaatta ttgatggtaa
    65581 gtggtatgga tagatatttc caaatagtta aatgctttag agatgaagac ttaagagcag
    65641 atagacaacc agagtttaca caaatagact gcgaaatgtc ttttgttgag caagaagatg
    65701 ttatgagtat gattgaaggt ttgcttgaag cgatatttaa agaagtttta gatgtagaat
    65761 tggcacttcc acttcctaag atgacttatg cagaagctat gtctaaatat ggttcagata
    65821 aaccagatac tagatttgga tatgagttaa cagatatatc tgatgttgtt tgtaactgtg
    65881 gatttaaagt gtttgctgat gctacacaac caggaaaaag tgttagaggt ataaacgtaa
    65941 aaggcaaagc tgacgacttt actagaaaac aaatatcatc actagaagaa catgctaaga
    66001 catatagagc aaaaggtctt gcttggatga aagtaggaca agaaggagta acttctccaa
    66061 tagcaaaatt cttcaatgaa gaagaaatga acgctatact tacaagaatg aatgctgaag
    66121 taggagattt acttttattt gtagctgata aaaactcaat agtatttgat gctttaggac
    66181 aagttagact tgaagtagca aataggctta atctattgga taaaaatgta tataacttac
    66241 tatgggtaac tgagttccca gtttttgaag aagatgaaga aacaggcaca ttctcagcaa
    66301 tgcatcaccc atttacatca cctatggatg aagatttaga caagttagaa gaaggtgata
    66361 agtcatcttt aagagcgaaa gcttatgata ttgtattgaa tggttatgaa ataggtggag
    66421 gaagtgttag aatatcaaat tctgatgttc aatcaagaat gtttaaagca cttggtttta
    66481 cagaggaaag agctaatgaa aagtttggtt atttattaga agcatttaaa tatggtactc
    66541 ctcctcatgc tggtctagct tttggtcttg atagacttgt tatgttactt gcaggaactg
    66601 ataatataag agaagttatt gcattcccta aaaatcaaaa tgctgtttgc cctatgacaa
    66661 atgctcctac attggcagaa gatgagcaat tagaagaatt aagtataaaa gttgatataa
    66721 aagataatga ataatatgta gttgcaagaa actaaaatgt aaaaagtctg gatataaagt
    66781 atatttatat tcagactttt tttattagaa ttattttata ttttttctct atatattttc
    66841 ataaattata cttgtattct caaccaatat aattaaaata ctatgtttaa aaattttaca
    66901 taaacttggt tgttttagaa actatttttt taatgagtac acgattttaa ttaaagaata
    66961 tataacaaat ttgaaataag tctaatatat gacttaatag attaaattaa aataataaat
    67021 ttggacgatt tatctattta taacttaaat tatatcaaat tgataacaaa ctagatatta
    67081 tacttttttg tagaatagaa ttacaattat ataaagaaaa attctattaa tagtgaaaaa
    67141 aaagtagaaa aaagtagaaa ttattctttt ataaagaaag ggagggataa tattgcaaga
    67201 gagagaagaa ttagttttaa atccagttcc aaaagaggaa agagttggat ggttagctcc
    67261 attgtttaat atgcttggtt ctaacatagc tatatctgaa ctaatggttg ggggaacttt
    67321 aattttagga atgactcttt ctaatatgat tattacatca attataggga acttaatatt
    67381 agttgcaatt attatgatac aaggttatat aggttacaaa gaagggttaa atacgtatgt
    67441 attagctaag ggggcatttg gagagatagg aggaaagtat cttatatctc tattacttgg
    67501 tataactagt tttggatggt ttggtgtaca agcaggggtt gcaggactat cagtacaaaa
    67561 gatattccca agtgtaaacc taacattagt tacagttata cttggattat ttatggttgt
    67621 ttttgcactg tatggtttta aagctatggc taaatttaat tacttagtta taccaccact
    67681 tatgatatta atggtgtggg gagtttttaa agctttttct acttatggag ttgaagctat
    67741 ttataattat actcctcaaa caactatgag tatggttgaa ggtcttaata ttgtagtagg
    67801 tcttgttata gttggtgcaa ttatatcacc tgaccagtta agatatacga gacgagtaaa
    67861 agatatttgg attatcagtt ttttaggtct agggattatt tcattattcc aacaagttgc
    67921 agctggtgta atgtctatgg gagcacctac ttgggatata acagaagtat tggctaattt
    67981 aggttttgga tgggtagcgt ttgttatttt aatacttgca tcttggtcta caaacgtatc
    68041 aaatgcttat tctggtggat tagcattaaa aactattttt ccaaatgtaa aaagaaatgt
    68101 tttgacttta gttgcaggtc taataggtac aataatagca gctactggta taatatttaa
    68161 atttcagtca tttttatctt tcttgggaat cgcagttcct gcaatagctg gaattatgtg
    68221 gtgtgagtat tattttatac aaggaagaac ttataagcat agagaaggaa taaattggat
    68281 tgcagtaata agctggttaa taggttttgc agcgtcgtat tatagttcaa aaataaattt
    68341 cttaatacct ccgataaatg gaattgtagt gagtatggtt atttattata tattaatgaa
    68401 atgttttgga atcaaagata aataaagggg gcaattacat gggtcgtaag gtgaaaatag
    68461 gtataattca acaacacagt gtacttggaa atgttaaaaa aaatatagaa aaggcagtag
    68521 agatgataga tgacttagga aaacaagggg cagatataat ttgtttacca gaactatttg
    68581 ctacaggata taatttagag tctttaggtg gagttaaaac attagaatta ataagagaac
    68641 ataataagta catagaggaa tcaatgtcag aagctgctaa aagaaataat gtatacctga
    68701 tatctccata tggaacctta gaaaaagggt ctacacatgt ttataattca gcagttatat
    68761 ttgatagaaa aggtaagatt atgggagaat actgtaaaaa tcatctgtgg tcattagaag
    68821 cagtatactt taaaggaggg gaaaaagtag aggtatatga tgctgatttt ggtagatttg
    68881 gtgtaatgat atgttatgat gcaggttttc cagaagtatc cagagaattg acattaaaag
    68941 gttctgaaat aatatttata ccatctgcat ggagaataca agatgaagat atgtgggatt
    69001 taaatgtatc tcaaagagct ttagagaaca ctgtatatac agtaggtgta aatttagtaa
    69061 gtaatgactc taatttaata ctatttggaa agagtaaaat atgcaatcct agaggtactg
    69121 taataactca attagataca tacagggaaa aatatgtatt atcagagatt gatttagatg
    69181 aaataaaaaa gtatagggaa gatatcccct atttgaaaga cagaaaaagt agctataaca
    69241 tataattcta tactataata caagttcaat ataaaatgat aaaaagagga tgtatcaata
    69301 ttaagattaa atttattata ctttgatata tcctctttaa tattatcaac tttgatttaa
    69361 atatttttaa aatagttgat aagaaagttt ttgaacaaca acacagcttt agattcatag
    69421 ttttcgctaa accatgaaag atttaaatat cttttaaatt caatatcttt gatatgtaac
    69481 aacttaatct cagggtcttg agataatccc catgattttc cacatataaa tccaactcct
    69541 tgaagtgatt ttataagagc ataaattgta tatggtgaat cagactcaaa tgctattttg
    69601 ggtttgaaat tagctgattc gcacaggata tcaattacct ctctataatt ctcacccttc
    69661 gttataacta taaagttttc atctgaaact tcgcttagat atacttcatc ctttaatgat
    69721 aaaggatggt ttattgaaac tcctaatagt atttcttcgc atgttaaagt tatgctattt
    69781 tctgagttta gctttgtaaa tgaagaagat atgtacaaat caaaatcact ttttttataa
    69841 gatgatggca aagtatgtga cacattaaaa gtaatattgg gatatagttt tctgaaatta
    69901 ctcaaaagtg atggtaacac attagccgct gcaggagata atatctttac ttctcctgaa
    69961 ttttctaaag aagtgtcttg taactccttt tttgaacttt ctactaaatc taaaatgcta
    70021 tctactcttt ttaaaaacaa tcttccatac tcatttaaaa caatatatct tccttttctg
    70081 tcaaataact gaactccaag ttctttttct aaggaagata tagttttgct taaagctggc
    70141 tgtgctatat ttaacttgtg tgatgctttt gttatgtgct ccattctagc aacagtttga
    70201 aaatacttaa gatgcaataa atccatagta taaaatacac ctcttttaat atgacttgag
    70261 ttatatcaat tttataatca actccacatt atacattata atataaagtt tatataataa
    70321 actacaatat attaaaaagt tatttaaatt gttatttata ttttgtacat aatctaatta
    70381 aaaaaagtaa ctttaaatga ttaactaagg aaatgttgtt acaaacttta gttatataaa
    70441 aaattcattt gatgagcaaa gtattaatgt caagtaagaa taaaagctta ttagataaga
    70501 aaaataatat tttataataa tgatgttact taaattatta tgttatacta ttttaaatag
    70561 gaaacattta gatactataa ttttaggggg agtcaagatg aaattaacta aatcaatatc
    70621 atcaatgctg tgcttatctc tagttttaag cttatcacca gtagcatatg caaatgaaat
    70681 aagtagaaca acagttgaga atactttagt aggtcaggat aggtatcaaa ctgctgttga
    70741 agtaagtaaa aaaggatgga gtagtgcaaa tgaggctgta gttgtaaata gtgaatctat
    70801 tgtagatgca ttagctgtaa caccatttgc taaattaaaa aatgctccta tattattgac
    70861 agaaaaaaat gatctaaatt cacaaactga gaaagaatta aaaagattag gagttaaaaa
    70921 agtttatata attggtctat ctagttctat atcaaatgat gtgcaaaaac agttagaatc
    70981 taataattta actactgata gagttggtgg tagtgataga taccaaacag ctttgagtat
    71041 agctaaaaaa atagaaggat taaaagatat atcagaaata gctgtagtaa atgggtacac
    71101 aggtcttgca gatgcagtta gtatagcttc tgtagctgct actaatggaa tggttatact
    71161 tccagtatct gatgcatctg gtatatctag ctttaaagat tttatagaat ctaagaatat
    71221 aaataaatca tacataatcg gctctactaa tgctgtatca gataaaataa aacaaagttt
    71281 acctaattca gaaagaatag gtggagcaga tagaaatgaa actaatggta aagtaataga
    71341 aaagttttat acatctaata aattaaacaa tgtatttgtg gctaaggatg gaatgaaaaa
    71401 tcaaaatcaa cttatagacg ctctagcagt aggagtacta gcatcaaaag aaaattctcc
    71461 tgtactaatc gtaggagaac aattaagtgc aacacaaaag agtgtatttt cgaataaaaa
    71521 tgctacctct ataactcaag ttggtagtgg aggaaatgaa aatgcattta aagaattaaa
    71581 agatttacag gcaaatagta acaataagag agtaatgtat gtaactaata cagataaggt
    71641 aaatataaga aatgatgcta caatagaagc ttctgttata ggatatctaa ataatggtga
    71701 tgaagtagaa gttttagatg tgttaaaaac tggatgggta aaaataaaat acaatgaagg
    71761 tattggatat gttagtgggt cttatttgac aaataataag cctgataata gtaatgaaaa
    71821 tataaaaata aagtatgtaa aagaaaaaga tggtctaaat gttaggaaag gaccaagtac
    71881 agaagatgaa aaaataggtc acctttcata tggaagcaaa gtagaaacaa tagaaatgtt
    71941 tgctactgga tgggtaaaaa taaagtataa tggtggatat ggctatgtaa gtaatgatta
    72001 cttatctgat acaccagtta tttaattata agtaacaata aaaaaactgc tttaatttgt
    72061 aaagcagttt ttttataaaa atttaagtct aataactatt tctattttga taccttaatc
    72121 ctgggattta ttattatgga tattatcaac atacaaacac tccaaatcca gtgtctaatt
    72181 ccaaacttag atattaataa attcagtcct gctatggtaa ataagcagta tttaattaca
    72241 attaaaagtg tatttataga aagccccttc atagaaagta tcctaaatcc aataatagac
    72301 attctaagtc ctataaatgc caataatata cctgcaatat cctgaattaa gtaatagtat
    72361 tcaaatttca tattcaatca actcttctct gagcagtatc aaatatttct aactcttcaa
    72421 tttcatcatc tgtgtatgta agcatagtaa aaccagttac accataaata aatgaaatta
    72481 taggtgtaat ccaacttaag aaacaatatg gaataaattc tagtgggctt acaccaagag
    72541 tctgagcaca gaaaacagca tttgaattcc atggtattaa tggaccacca agtgtagctg
    72601 tatcttctat aattctagat agattttgtg gttttaattt aaattctttg tatattggag
    72661 acattagagt tccgacaaat acagaagtga acatcattga tgaactaaat gcatttgcaa
    72721 agtagcttac tataaaagta gacccaacca atttagttct tgattttcct attttagtta
    72781 taagaggttg aagcagtact tctaagaatc cagttttttg gagaatacca gcaataacga
    72841 aaactacaaa tactagtaaa acggtttcag ccatactcat tattccacca cgatttaata
    72901 gtttgtcggc atagacaaat ccagtatcta tagtaaatcc tgatagcatg taatttaaaa
    72961 catcacctat tttttctcct tcttgaaata ctgctataat aagtcccatg atagctgaac
    73021 ttagtataga tataatgggt ggcttttgta gcaataaaag taataataaa aatattattg
    73081 gaatcattgc tactaaacca atatgaaagt ttgaatttaa tacatccttg atttgattta
    73141 tttgaacata gtctatagta ttatttgagt acttaaatcc aattactgta tacagaacta
    73201 tacatattac gtatgcaggt cctgtggtat aaaacatatg cttcatatgt gtaattacat
    73261 ctgtcttaca aactgctgca gctaagtttg tagaatctga tagaggtgac atcttatctc
    73321 caaagaaagc accagaaatg actgcaccag ctgttaaacc aagaggaata cccatactag
    73381 taccaatact catcattgct ataccagaag ttccaagagt cccccaagat gtaccagtag
    73441 caacagaagt taatgaacat acgattaatg ttgtaagcag aaaatattta ggggttatta
    73501 ttgttagtcc actatatact actgttggta ttgtaccagc agctatccaa gctgctatta
    73561 gtacaccaac agaaagtata attaagtttg attgaaaggc atctttacca acttcaaatc
    73621 caaaagcttc tatttcatca ttagtataac caagtttcat ggctgcagga actactataa
    73681 gccatgaaag taaaaacatt gtagttatag aagcattaaa tacaactata ccaactgatg
    73741 ttagagctat tattgcaagc attactaaca aggaatatct aaatgaaggt atttttcttt
    73801 ctgtattcat tttcatagtg caaattctcc ttaaatattt ttagttaatt gcatttttta
    73861 ttcttataag agcttcttca agcatacttc ttggacaagc taagtttatt ctttgatacc
    73921 cacttcctcc aatgccaaag ctgtttcctt gatttagagc aactttacct ttttgtacaa
    73981 gtatactttc tagttcctca tcacttaatc caagtgcact aaagtctacc cataataaat
    74041 aagtaccttc tggttttcta actttaagtt ttggcatatt ttcatttata tattttatag
    74101 caaaatctat attagattct aaatattcta aaaatgattc tagccaagat tcaccattat
    74161 tatatgaagc ttcagttgca actaagctaa agcaattatt tctctttata tcaattctgg
    74221 taaaggcatc atctaacaat ttatagtctt tttcatcagg tagtattaca tatgatgatt
    74281 gaagaccagc tatattaaaa gttttagttg gagccataca agtaattgta tttttttcaa
    74341 attctttaga aatagatgcc ataggaatat gcttatgttt ttttaatata atgtcactat
    74401 gtatttcatc agatatgatt tttacattat gcttaagaca aatatctcct agttttttta
    74461 attcatcttt tgtccatact ctaccaactg gattatgagg attacaaagt atgaataatt
    74521 ttacatcttt aatcttgttt tcaatgtctt cataatccat tatgtagtct ccattttcta
    74581 gtttttgtaa tgggcttata attagttctc tattgttatt ttttacaaca ctattaaaag
    74641 ggctgtaaac tggttcttgt atcattattt tatcatttgc ttttgtgagt tcatttatta
    74701 aaagacttat agctgggata acacctggac tataaattaa ccactcactt tttattttcc
    74761 agttatgtct cctatctagc cagtttacta tagattcatt gtaagaatct ggtcttgttg
    74821 tgtagccata aatctcttgt tctagtctat tttttaagga atcaattata caaggtgcag
    74881 ccttaaaatc catgtcagcc acccacatag gaagtaaatc attagttcca tacttttttt
    74941 ccatttctga ccatttagat gaaaaattat tgcttctatc aacaatctca ttaaaattat
    75001 aattcattgt aaatacctcc agtaatttta attttatgtt aataatatta agcaaacaac
    75061 gtgccaatat tgataataaa aaatatttat tcacaagtta atatttaata ttaagtaatt
    75121 tcagagcata gataagataa aaatattaat tatacttaaa actttgtgga aaaggttatt
    75181 tctaataaat ttttaaatat atgaaaatgt aattaaatag gttaaatagg tttaactgtt
    75241 taacttgtta gacctattta tattttttag aaattctact ccttttgatg ttataattga
    75301 acctccacga ccaacaagta tgtctacaag cccaaagtct tgtagttcta aaagcatatt
    75361 tctaatctgt tgttctgtca aaaatctatt ttcctctaaa gctattttac ataagctttt
    75421 tctacctatt ctttctttta aatcataagc cttttttaaa ttatccaata taaatatgta
    75481 ttcatctagt gaccttttaa aattatagtc gtatttcatg atgtttttgt ctttgccaat
    75541 gttgaattga tactttttta tattatcact tactttatta caaacggttc tactataatt
    75601 tgaatctatg gtatctaata tatattcagg taaatcacat atttctataa tatctttttc
    75661 caagtaacag aagtattctc ctaagtttct taattctctt acatttcctt cccatctata
    75721 cattttaaag atttctttta cttcctcact tagaataaaa ttacatggaa tatcatattt
    75781 taatgaacca aaaatttcaa atatatcagc aggtctttcc ctaagtggat gtattttaag
    75841 gggaagaaca ttcaacctaa aatataaatc tcttctaaac atatttttag atacaagttc
    75901 ttttaaattt ctattagtag ctgcaattat tcttacatca atgtcaatga cattattaga
    75961 accaatacgt cgtacttgtt tttcttgtat gactctaagt aatttagatt gagaatttaa
    76021 atccatttct ccaatttcgt ctaaaaatat agttccattg ttggctaatt caaataaacc
    76081 aattttccca ccttttttag caccagtaaa agccccttca tcatagccaa ataattcact
    76141 ttgcagtaga ttttcttgaa aagtactaca atttactgcg acaaaaggac catcttttct
    76201 cctagaagca ctatgaatgg attgagcaaa taattcttta ccagtaccac tttcaccaat
    76261 tataagtata gatgaatttg attgagccat tttattagca attttttttg tattaatagt
    76321 ttgtatacta gaacctaata tatcatcaaa tgtgtattta ctgatattac cagagtttac
    76381 tagttgtgct cttaatttag cttgcttttt ttctaattga gaaaactttg tcatctttag
    76441 tataaatcca tcaaatacat ttaattgtat atgtttaatc tctaaattta tatcaatatg
    76501 atttatttta atcaatttct caaaaaatgg agttttattg gtcaatatgc tttgaaaatt
    76561 gatgtctttt atgcaatcac caacaaatga gtcaatcatt tcatttgcat ttatagacaa
    76621 aatttttcta gccatatgat tatagaattg aattattcca tcgttatttg tgcatataat
    76681 tccatcatca attatagata gtaacaaatc aaattgtctt tcaaacttat ttgcatctaa
    76741 caataactca cctgtactat aacttgtagg aattattttt tctacgtatt tttttattag
    76801 gtcatctttt attagatgtt ttaatttggt ttttgcagca atttcaacaa tacaacttaa
    76861 atctattatt ctgtatttta aatctataac ttcacaattt ttaaacttag gcaagatttt
    76921 ttcgccagga gttaggatta cagcatctgt gggagtaaac tcaatctctg gatagcaggg
    76981 caggatattt atattgtcta ttcctaatct atgtattaaa gaaattgttt ctattgccat
    77041 atctttactt aagttatata cataaataat tttatctttt tctaatttgg atatcatatc
    77101 aatactgttc ttttcaaatg tcaacttggg aacaatgatt tgagcatcat agtgagataa
    77161 ttttactatt tcatcatatt ttaaataagc agataggagt ataagttttt ctttaaaaaa
    77221 ctttaaattt ccctcttcaa atgagtataa atttatcttt agattatcac ctaagaattg
    77281 ccttatttga ttttcataaa tttctccagc gtcttttttt aaacttacaa tagctaattc
    77341 catttgtttc attttaacct ctcatacaaa tttgacttat tttagattac ataataatta
    77401 aattaaataa tattatttaa ttattattat aaatttatta tagactacac attgaagtaa
    77461 aagaagtagc taaaattatt ccttttattt ttgttttttg tatctatttg gtataatagt
    77521 attagagcgt ataataattt aggcaaaatt ttttaaggaa gactagagga gaatataaaa
    77581 tgaaaaaatg tctttactgt aatagggata taaagtcacc aaataataaa ttagctataa
    77641 aatatgatga caatatgaat atatatccat gtcgtgcaga atgtaaggaa aaaattgaag
    77701 aatatatagc aaaaaaacct acatataagt ttataaatat attagaggtt cttttaggtg
    77761 tgggcggaat attctgcttt ttgagtaaat ggactattgc agcccaagtt gtacttggaa
    77821 ttgatgcatt ggttatattt ttattcccat tggcaggatt taagatgaat ggaaagttaa
    77881 gtatggaaca aactaagaat caaagtaggt ctattgcaat atcaattttg gcatttatag
    77941 taataataac tgtattatat tttaaacaag ttggtaagta gagcataatt gtataagaca
    78001 tcattagagt atgaggtgag tttatggaag aaagaaaatt agcaccaaac aatgagaggg
    78061 aagctctcat aaaaagatta aaaagaatag aaggtcaagt taagggtata caaaagatgg
    78121 tggaacaaga acgttattgt gttgatatat tggttcaaat atctgctata aggtctgcta
    78181 taaatagagt aggcacaatt atcttagaga atcatataaa aggatgtgta gcagaaagca
    78241 ttaaacatga tgatgctgat aaaactgaag agatgataaa agagcttatg gatactataa
    78301 ataaattcac aaaataagga ggcggttagt tatgaatcaa caaggattta ttatggaaat
    78361 tgttgatgat agaactgcaa agttaaaaat gcaaagacat tcagcttgtg ctgcttgtgg
    78421 aaaatgtgct actacaaatt cagcagagtc aaaagaaata ttagtagaag tagacaacac
    78481 aattggtgca aaagttggtg accatgtaga agtgagtatg gataatatga atgtattaaa
    78541 agcagctgta atggcttata taatacctct tatagcactt cttgtaggaa caatagggac
    78601 ttattatata ttgggggcaa ttggaatgac aactggagtt gaagccataa gtggattagt
    78661 tggaatttgt cttacaataa tctgttattt atacttaaag aagaatgaca aaaaatttag
    78721 agacagtaga gaatttatac cagtaataac aagaatatta attgaccttt aagataatta
    78781 taattaaaaa atagcaatgt gctttttaaa taaatactca atacgtattt gtagagttta
    78841 agtacattgc tatttttata tttttatttt gattttttgt aaggaataaa gttttttctg
    78901 attttcaaaa gattcaatgt tcttacaaaa gaagttacaa ctaatacacc aagtgctatt
    78961 gcagcactta gaaatagcgc atctgtacct tttgacatag ccaaagaata atttttctga
    79021 atcaaagaca acattgtatt atatagccca attcctggta ttagaggaag aatacctgga
    79081 attacgaaca caatagctgg ttgctttagt tttcttgcta aagtctcact gcacgctgag
    79141 accaaagcag cagcgataaa acctgcaaaa actgcatttg tagtaaaatt aaataaataa
    79201 acatatacaa tccaaccaat tccgccagtt actccagctg gaagaagtag atatagtgga
    79261 gcattaaaga aaacagcaaa tccagcagtc gcaacacctg aaaataaaaa atgcaaaatc
    79321 atagacatat cagtcattag aaaggacctc ctattctata ccatgtatca aggacaaaac
    79381 caactccaga agcaattgca ataataatca tagcagcatc aaaagcacga gaaattcctg
    79441 atattaaatt ccctgatatt aaatctctaa tagcttttat aaaagcaact cctgggagta
    79501 gtggcattat agcgccgact ataagcattt tagggtcatc taaaatgcct atttcaacta
    79561 gtagaactcc tgaaagtgca attaaaaaag aagatactaa acaggaaaat gcagatattg
    79621 cacttatctt catcgtttta tcataagtaa ttgcagcaaa gattgctatt ataaacgtaa
    79681 gtataaaatt taatacataa ttccctccaa gcaaacaagc aaaacaagca gatgcaattc
    79741 ctgtacaaga gtaaaataac cataaaggat aaggttttac atcttggatt tcataaagac
    79801 gtgcaatggc attatcaata tcatactctt tgtcactaac aaattctcga gaaaaactgt
    79861 ttaataaaga aatcttattt aagtttatac ctcttgattg aatcgttttc ataaacgaaa
    79921 agccatcaaa tttctcatct gaaataatta ttactgtagg agttgtaaaa atatttacat
    79981 gataaaaccc tcttgacctg catattctaa ggacactgtc ttcaacccta gatgtttcag
    80041 ctccattttt tatcatcagt tcccctacaa atagagctag ttttagaata tttttcttat
    80101 attcaagttc ctcattttga ttcataaata cacctccaaa ttaaaaaacg taatattgaa
    80161 attatatcaa atttttaagt aatattcctt aatatctata taaatatatt atcttttttt
    80221 tgtttcaaaa tagtcacatt taaattatat ccaattaaaa gaattagaca atattattta
    80281 ttatatttta acttaaaaat aaagaaagta actatgttaa atatggaaaa atggcaaaac
    80341 acttgactat taattggtaa aggactataa taataaatta tcatattgat aaaaacgaaa
    80401 attatgaaat gtctgtaaaa ataaaattta aataataact aggaggagta atatgtttga
    80461 gaacttgaaa aaagcggacc ctgagattta tgaaagtatg aaaagagagt taaaaagaca
    80521 acaaagaaat attgaattaa tagcatctga aaacatagta tcagttccag taatggaaac
    80581 tatgggaagt catcttacaa ataagtatgc agaaggttac tcaggcaaaa gatattatgg
    80641 tggatgtgaa tacatagatg aagttgaaac tcttgcaata gatagaatca aaaaaatatt
    80701 tggagcagaa catgctaatg ttcaacctca ctctggagca aatgcaaata ttggtgtata
    80761 ttttgctatg ttaaaaccag gtgatgttgt tatgggaatg aatttatctc aaggtggaca
    80821 tttaactcat ggtgctccag ttaatatttc tggtcaatat tataaatttt atgaatatgg
    80881 tatagataaa gacagtggac ttatagattt tgatgaagtt agaaagatag cacatgaagt
    80941 aaaacctaaa atgatagttg caggagcaag tgcatatcct agagaaatag attttaaaaa
    81001 gtttagagag atagctgatg aggttggagc attgcttatg gtagatatgg ctcatatagc
    81061 aggtcttgtg gctgctggtc ttcaccaaaa tccatgtgaa gtggctgatt ttgttacaac
    81121 aacaactcac aaaactttaa gaggacctcg tgggggtgtt attctttgta aagaaaaata
    81181 tgctaaagac atagacaaag caatattccc tggtattcaa ggtggacctc ttgaacatat
    81241 aattgcttct aaggcagttt gctttaaaga agctttaagt gatgagttta aagaatatca
    81301 ggtacaagtt gctaaaaatg caaaagcctt agctgaagaa cttattaaaa gagattttaa
    81361 attgatttct ggaggtacag ataatcattt aatactatta gatttgacta ataaaaatat
    81421 aactggtaaa gcagcagaaa agagattgga tgatgcttat ataacagcta ataaaaatac
    81481 aattccattt gacccaaatg gtgctcttgt tacaagtgga ataagacttg gtactccagc
    81541 tgtaactact agaggtatga aagaagaaga tatggcaata atcgctgagg ctatagacct
    81601 atgtttaact tatgatgaag aatctaaggc tagaacattg gttgttggtt taactgaaaa
    81661 atatccttta tatgaagaat ataatattat ggattaatta taaagaacaa ctaaataaaa
    81721 tacatttaaa taattacaat gattgtgtat gtatttgaat atatttagat ataaaaaagg
    81781 tgtctcaaaa tgaacttttt agtttatgag gcactttttt gtatggaatc gaacatattt
    81841 gtattattta aataataaaa aatatggtta tctctatttt tagatggtct ctttgtattt
    81901 tttaattaaa actttaagat ttcttaagaa ttatactagg tttttctaaa gatttaaagt
    81961 ctatacttat aagtatagta atcatatgaa aagaaaagct ttaacgagga gggaatctta
    82021 tgaaggtatt aattcttaca ggaaaatttg gtatgggtca ttactcagca tcaaattctt
    82081 taagtgaaga tataaaagca aaatttgata attcagaaat aataattaaa gatatatttg
    82141 agtacattat gcctaactat tcagataaaa tgtacaagac tttttctatt cttgtaaatc
    82201 ggggaagtag tctttataat ttgttttata aatgtgctga aaatggaaag aaagatataa
    82261 aatttacttt ttcagattat tttttaaata aattagatac attacttcat gaagtacaac
    82321 caacagtagt tatttcaact tttccatttt gttctcaatt agtatcaaga tataaggaaa
    82381 aatataactc aaatcttcct ttaataacat gcataactga tataagtagt cactcagaat
    82441 ggattagtaa aaatacagac tgttatttag tagctagtaa atctactaag gaagaacttg
    82501 tttttaaagg aatagatgaa tctaagatta aagttaatgg tattccagta aaaaaagaat
    82561 ttaaaagaat agaacatgta aatcattcaa ctaaaaaaaa tattcttata atgggtggag
    82621 gattaggatt actgcctaaa tcagaacaat tttacaaaga attaaatagt ttagaaggag
    82681 taaaaactac tgtaataact ggtaataata aaaaaatgta ctataaacta tatggtagat
    82741 atgaaaatat agaggtagta ggttacacca atgaagtata taaatatatg aaagattctg
    82801 accttattat ttctaaacca ggtggaataa cactatttga aacaatttat tcagaacttc
    82861 caatattggc atttaatcca tttttacaac aagagataga taatgctagt tttatattaa
    82921 ataatgaaat tgggagaata cttggtaaaa ataaaaaata ctatgtagat gagataaaag
    82981 atttaattta tgatgatgct actcttaaag aaatgagcag taacatgaaa gaattaaaaa
    83041 aacaatttga taataatacc ttagagaata ttttattttc acttgatgaa caaggagcgt
    83101 gtagagaatg tatgtagtag gtttaattat cgttgttgca ttgatttttt tagtccattc
    83161 aattatacct acatactata ataaactatt aaataaaaag gtattaaaaa atatggctgg
    83221 agaaaatgaa attgcactta catttgatga tggtccagat aagagatata cagaaaaatt
    83281 actagatgtg ttaaaagaaa atgatataca agctatgttt tttgtagtag caaagaatgc
    83341 tgaaaaagag cctgaaatta taaaaagaat gttgagagaa aatcatatag ttggtttaca
    83401 ttcattggaa cacagaaatg catggcttta tagttatagt tatgttaaaa aagattttat
    83461 tgaaagtaca aatataatga aaaatttagg tgtagatgta aactactatc gtccaccatg
    83521 gggtcatact aatatatttt caaattcatt tgttaaaaaa tataatctaa aaatgacttt
    83581 gtgggatgta atggcagaag attgggagaa agatagtaca gtagacatta ttataaacaa
    83641 gttaatgagt agaacaaaag aaaattctat aatttgttta catgatgcag gtgaaaattc
    83701 aggtggtgca gtaggtgcac ctgagcgtac tattgaagct ttaaagatag ctattccaaa
    83761 acttaaagcc agtggtttaa agttcgtaac accagaaagg atgtagttat gataagtaaa
    83821 actgaaaaga aaaataaatg cctaggtagt gtagcttttt tagttttact aatgggcata
    83881 acaggatatt ttgtttttag agggcagtca gttgaatcat tgataaaatc attaaaaggt
    83941 gcaagcccta tgtttatact aattggattt gcaatgatgt ttatatatgt tgcctgtgaa
    84001 ggtataaata tatacttagg tatgaaagct ttaaaccaaa agactactct tttaaaatgt
    84061 atgggatatg cttttattgg attttatttt agttctatta caccttcagc atcaggtggt
    84121 caaccagcac aagtttatta tatgaaaaaa gacgatataa atatatcata ttcttcactt
    84181 atactattag tcattgttgt tattcaccaa gtagttatac tggcatatag tggaataatg
    84241 ttcattatgg aacgtgagtt tatattaaat aatgtaagtg gtatgaacat tttactaata
    84301 tatggtgtaa taacaaatgt tgctcttgtc attggagtaa ttgcaattat attttcaaaa
    84361 aaacttgtaa acaattttat aatatcaata acaaatttat taggtaagtt aagaataata
    84421 aaagatgttg aaagttcaag aaaagttata atatctcaaa ttgaagagta tgttaaaggt
    84481 gctcaatata taaagcagaa tccaaaactt gtagtccaaa ttttagtcat aactattgta
    84541 caaataacag ctatgttttt agttcctttc tttgtataca aagcttttca tctatcaaca
    84601 tatactgtat ttgagatatt agcgatacaa tccttgctta atattgctgt ttcttcatta
    84661 ccattgccag gggctgttgg agcttctgaa aatagtttta tgacattatt taagatattt
    84721 ttccctggtc acttattagt tccggcaatg ttacttagta ggggaataag tttttatgca
    84781 tttgtagcta taagtggatt gatatgtata gtagtacatg taaaatcttc tgaaaaagta
    84841 aaagcagtga aaaaagttgc ttatgtaaga taatattata tagattattt ttattaatat
    84901 gtcaatttgt gtgtatattt taattaagct ttaaacatgt ttacaggagt agaaactatt
    84961 aaaacgtgtg acattgctaa gcttttgcta ataaagtata atattttata tagtttgaaa
    85021 tatttaagaa atatagcaaa aaaaggagct tggtgatgaa taaagagatt ccaaaaaaaa
    85081 ttttagtagc tgatgataat cctgagatta gggaaatcgt agaaatactt ttaactggtg
    85141 aaggttatga agttattatg gcaacgaatg gagaagaagc tgtaaactta gtagatagta
    85201 cgattgattt gattattttg gatgttgtaa tgcctgtaaa aacaggattt gttgcatgta
    85261 atgaaattag agaaaaaacg acagcaccaa tattattttt aactgcaaaa actcaagact
    85321 ctgataaagt tattggattt tcagcaggag gagatgacta tttatcaaag cctttttcat
    85381 attctgaact aatttcaagg gttaagtcgc tacttagacg ttattatata taccagggaa
    85441 aggaaaagga aagagagcca aatatattaa aaacaaaaga gttatgtgtc aatttagata
    85501 ctcaagatgt tacactaaat ggagaacctg tgtttttgac aactatagaa tatagtatat
    85561 taattcttat gttgaaaaat agaaaaaaag ttttttcgtc tgaaaattta tatgaaacta
    85621 tttgggatga gcagtatttt tatacagcaa ataatacaat aatggttcat attagaaatt
    85681 taagaaaaaa gttagaaaaa gaccaaaaaa atccacaata tataaaaacc gcatggggaa
    85741 aggggtatta tattgattaa caaaattaag ccatctaagt tgggagttat actattgata
    85801 tatgtagtaa tctcagctgc agtggctttc attttaaata taccatttta ctctgctgtt
    85861 gaatctatag taaaagatgt atcagaaggg aaagtatatt ttaaaagaga agtaaatcaa
    85921 cttatggata attttcaaac ttatgtgaat aacaatggta taagagcaga tgatggagat
    85981 gatatagcaa aatggaatag tgataattgg tttgtttcta tgaagatata taaaggaaat
    86041 aaggtttttt atgatacatt atactatcct aatgaagtac ctgataagag tgaggaaaat
    86101 gagttttata gcagtcccat ggctagaaac tatgagatac aattttctga tattaaagct
    86161 aatatagttg tagtagcttt atttagattt agatttcaaa attttataga agcaatttct
    86221 attacattta tggcacttac atttattata acatttttac tgttgtttag tagaaagata
    86281 aagtacctaa ggaaaataga aatgggtata aagatagtag agagtggcag tttaaagtat
    86341 agaatcccag taaaaggtaa tgatgaatta tcatcacttg catctagtat taatgagatg
    86401 agtcatacat tggagaatca acttataaaa gaaagggaga tgaagaataa aaataaagat
    86461 atagtaactt cgatatcaca tgatgttaga actccattaa cgtcagtaat ttgttattta
    86521 gatttgatta aagaccataa atacaatagt cctgagcaat tggaacaata cataaaaaat
    86581 gtaaggtcta aagcatatca aataaaagat ttaacagatg acctttttac gcattttgtt
    86641 aattctggag aggaagtttc aaaagggtat gaaaaaataa atgctaatga atttattttt
    86701 caattacttt tagatagttc atatacattg gaggagaaag gatttcatat aacaatagaa
    86761 aatgaacttt ataaccaata tcatatttat gtagatgtta cacaatttag aaggatattt
    86821 gataatttat gttctaatat aataaaatat gctaggaaag ataagcctat agtattttta
    86881 attaaagtag aggattctaa attactaatt atacaaaaaa atagagtaag taatttttct
    86941 aagaatgtag aaagttttgg aattggtata aagaattgtg agaaaatagt tgcatatcat
    87001 aatggaagca taaatgtaaa ttcagatgat aaagaatttg ctattgaaat atctattcca
    87061 gcaaaagaat cataaaaatt taaattatat attgtgtagt tgctattata tattgtgtaa
    87121 ttgcttatgt aaaattctat gaagcaggaa gcatgtgact ttagttatgg gatgttcaat
    87181 attgtgtacc tctaggcaag taacaagttt acttacaaga ccatataata ttattatctt
    87241 aaaaaaaggg gacataataa tatggttttg acaggagcac attatattta cattctattt
    87301 atggtaatta tattaattac tatgattatg aaaaaggata caatagtacc atgtatatta
    87361 ggtgtttttt ttatgggatt gttctttgaa aaaaacattt ttggtgctat aacagcagtg
    87421 tttaactctt ttattatatc tttaaatgag ttgggtccaa ttatcttgat tatagctatt
    87481 atggttgcat tatctaaagc cctagaagcc aataatgcta tacaatatat ggtgagacca
    87541 ttttcgagag ttataaaaaa ttctaataca gcattttttg taactggatt tgttatgtta
    87601 gttctttctt ggtttttctg gccaactcca gctgttgcct tagttggagc tgtattttta
    87661 cctgttgcta tgagagctgg gctaccagca attggtgttg cagtagcatt aaatttattt
    87721 ggtcatggtc ttgccttgtc tacagacttt gttattcaag gagctccaag tataacagct
    87781 ggtgcagcag gtgttgcagt atcatatgtt ataaatgatg gtatgatttt gttttgggtg
    87841 atgggaatcg taaccatatc tatggcattt tatacattaa aaagagatat taacaaagga
    87901 atgtttagag aagaactaaa aggttttgaa agtgaagaag tagaagagtt caatggaaaa
    87961 tctaaaatag caactatttt agtagctctg ggatttcttg ctgatataat tgctatgtat
    88021 gtatttgacc taaaaggagg agatgcatca gctcttttgg gtggaacagc agtattttta
    88081 ataataatta taaatgttat aaattttggc aaagatagtc ttgaaaatgt atgtgagaat
    88141 ataattgatg gttttgtgtt tgggataaaa atatttggag caattatacc aatagcagca
    88201 tttttctata tgggtgaagt tgcaccattg acaggtgtat ttggaaaagt attagcacca
    88261 ggttcacaag gtttattatc agatataggc atagctcttt ctcaaacaat accacttaat
    88321 aaatttgccg tatcaggtat agaaactgta gtgggagcaa taactgggct tgatggttct
    88381 ggattttctg ggatttcatt agttggttca cttgcctctg tatttggaac tgctataaat
    88441 gcaagtgttg gtgcattagc tgcattagga caaatcagtg gtatatgggt aggtggaggc
    88501 tgtctagttc cttggggtct tatttcagca gcggcaattt gtggggttag tccaatagaa
    88561 ttggcaaagc gaaactttgt cccagttata accggattgg ttgtaacaac catagtagca
    88621 atgtttatta tttaataaat cgaataaatc tttaattgta taaattaaaa atagatgtgt
    88681 agctataatt tattataatt gttttactaa ttctaagcca tacatctatt tttattgata
    88741 tttttattag tattctttaa taaagtaata tttttcatta tattatacat aacatctaaa
    88801 tataacatct aaaatactgt tatctatatt taatatcttg ccaaattttt tgatgtttta
    88861 ttgccctgtc ccaccaacat atataagcta tcacaagttt ttacctatac tatcaccaaa
    88921 caaaaattct aattttaatt tattatttta taacctatat tatattaact atattagttt
    88981 gtagacttta gatgtaatta taaatattaa tactccaaga gttcaaattc atatcctagt
    89041 tttcttgcat ttgatataaa atcatttaaa atttctgtac tagttttgga aactgcatgt
    89101 agtaacaaga tagaaccatc atgtagatta tccattattt tttgcgttgc ttcttcatgt
    89161 gatggttgtt tatcagtatc ccagtctctg tatgcaaaac tccaaaatac agtcttgtat
    89221 cctaaatttt tagtcattgc caagcttttt tctgagtatt ttcccatagg aggtctaaaa
    89281 aatttaacca tatctttccc agttacatct ttatataact tttcaacatc atataattcg
    89341 tcattaaagt tttttagatt gcttgttttt gttggcatag atggatgggt tttactatga
    89401 tttccaacta tatgtccctc agaaaccatt ctttttacta aatctttatt ttcttttata
    89461 tatggagctg taacaaaaaa aactgcttta acctggtttt gttttagagt gtcgagtatt
    89521 tttgtagtgt atccattttc ataaccttca tcaaatgtaa gatatagtgt tttttgacca
    89581 tcttttgtag gtccattgta tagggcatca tagtcagaaa atttaaattc aatgtccgta
    89641 tttacttctg gtgttttatg cttattgttt ggtatataaa accaatcaag agtagtgtta
    89701 tctaaagaag atacatctaa tttattatta tcattattag tagtggcttt tgatggttta
    89761 tctgttccgt ctgaaactat tacattggaa gtatctttac cactatctat tttttcctta
    89821 tcttcttgta actgtgtttc cttattttga ttttcgtttt gattgttttg tgaatttgaa
    89881 catccaacaa taaaaaaaat agaaatagaa agtagtgtta aataatgcaa tacttttcta
    89941 aacattttga agctcctttc taaattaata ataattgcat ataataataa ttatatgatt
    90001 aattacaatt gcatatagta ttattataat tggaaattac tattaataat agttatatct
    90061 ttaaaaataa agtcacaata gtatgacaaa gggtgaataa tcaataaatt taaaaaaaaa
    90121 tgaaaaaaat agttgaccat attatgagaa gatgttatta taataaatgt gctcaacaag
    90181 aagtaacaaa ataacaagca caaagaagtt aattgaat
//
LOCUS       DAEPUT010000006        74449 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.006, whole genome shotgun sequence.
ACCESSION   DAEPUT010000006 DAEPUT010000000
VERSION     DAEPUT010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 74449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74449
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.006"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            131..2032
                     /gene="cooS"
                     /locus_tag="KRL22_000531"
     CDS             131..2032
                     /gene="cooS"
                     /locus_tag="KRL22_000531"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH1271054.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            2025..2498
                     /locus_tag="KRL22_000532"
     CDS             2025..2498
                     /locus_tag="KRL22_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1271055.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSRHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            2473..3699
                     /locus_tag="KRL22_000533"
     CDS             2473..3699
                     /locus_tag="KRL22_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1271056.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(3838..5025)
                     /locus_tag="KRL22_000534"
     CDS             complement(3838..5025)
                     /locus_tag="KRL22_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1271057.1"
                     /translation="MNITKNFLKDYLERFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNTRIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            5298..6122
                     /locus_tag="KRL22_000535"
     CDS             5298..6122
                     /locus_tag="KRL22_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1271058.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVYKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            6251..7516
                     /gene="gluD"
                     /locus_tag="KRL22_000536"
     CDS             6251..7516
                     /gene="gluD"
                     /locus_tag="KRL22_000536"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HBH1271059.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            7729..7842
                     /locus_tag="KRL22_000537"
     CDS             7729..7842
                     /locus_tag="KRL22_000537"
                     /inference="COORDINATES: protein motif:HMM:NF017390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271060.1"
                     /translation="MHFKSKDFHLKYLVLFLKIVYWFNPFIYNGKIYGFGL"
     gene            7826..8317
                     /locus_tag="KRL22_000538"
     CDS             7826..8317
                     /locus_tag="KRL22_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBH1271061.1"
                     /translation="MDLDCEFYCDERVLKNCTVQQKQEYALTIVNSMKRGTNFSNKFV
                     AGLNKQSDIRKRVINMFSEKYKNGILMALIISLFSSITFFKFDSTSIIEENDFLERSR
                     YTFEGRQEDVFVTIDFIYADAPIKLRKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMD
                     LKK"
     gene            8647..9780
                     /locus_tag="KRL22_000539"
     CDS             8647..9780
                     /locus_tag="KRL22_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBH1271062.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDGEIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGMEEKDVTNSAIVTMIEF
                     TYAEAPKSMRERYKINCEFLGLIPKDSDKIGVGVEYYDSLLND"
     gene            10696..11718
                     /locus_tag="KRL22_000540"
     CDS             10696..11718
                     /locus_tag="KRL22_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH1271063.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            12014..12934
                     /gene="pyrB"
                     /locus_tag="KRL22_000541"
     CDS             12014..12934
                     /gene="pyrB"
                     /locus_tag="KRL22_000541"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBH1271064.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILDLAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            12973..13665
                     /locus_tag="KRL22_000542"
     CDS             12973..13665
                     /locus_tag="KRL22_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBH1271065.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            13658..14560
                     /locus_tag="KRL22_000543"
     CDS             13658..14560
                     /locus_tag="KRL22_000543"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH1271066.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETSSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            14645..15229
                     /locus_tag="KRL22_000544"
     CDS             14645..15229
                     /locus_tag="KRL22_000544"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBH1271067.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            15444..16370
                     /locus_tag="KRL22_000545"
     CDS             15444..16370
                     /locus_tag="KRL22_000545"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBH1271068.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(16422..17312)
                     /locus_tag="KRL22_000546"
     CDS             complement(16422..17312)
                     /locus_tag="KRL22_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1271069.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            17500..18531
                     /locus_tag="KRL22_000547"
     CDS             17500..18531
                     /locus_tag="KRL22_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBH1271070.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPQEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            18825..19700
                     /locus_tag="KRL22_000548"
     CDS             18825..19700
                     /locus_tag="KRL22_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxoguanine DNA glycosylase"
                     /protein_id="HBH1271071.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYAEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            19718..21208
                     /gene="cls"
                     /locus_tag="KRL22_000549"
     CDS             19718..21208
                     /gene="cls"
                     /locus_tag="KRL22_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH1271072.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSYCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            21401..21685
                     /locus_tag="KRL22_000550"
     CDS             21401..21685
                     /locus_tag="KRL22_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBH1271073.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            21718..23346
                     /gene="groL"
                     /locus_tag="KRL22_000551"
     CDS             21718..23346
                     /gene="groL"
                     /locus_tag="KRL22_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBH1271074.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            23608..24348
                     /gene="larB"
                     /locus_tag="KRL22_000552"
     CDS             23608..24348
                     /gene="larB"
                     /locus_tag="KRL22_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HBH1271075.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            24432..25166
                     /gene="larC"
                     /locus_tag="KRL22_000553"
     CDS             24432..25166
                     /gene="larC"
                     /locus_tag="KRL22_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HBH1271076.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            25196..25615
                     /locus_tag="KRL22_000554"
     CDS             25196..25615
                     /locus_tag="KRL22_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HBH1271077.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      25675..25776
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            25997..27532
                     /gene="guaA"
                     /locus_tag="KRL22_000555"
     CDS             25997..27532
                     /gene="guaA"
                     /locus_tag="KRL22_000555"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBH1271078.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            28071..29501
                     /locus_tag="KRL22_000556"
     CDS             28071..29501
                     /locus_tag="KRL22_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1271079.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDID
                     NNTERYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKSDGMVQIVVMNNNKPVSYIYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(29649..29999)
                     /locus_tag="KRL22_000557"
                     /pseudo
     CDS             complement(29649..29999)
                     /locus_tag="KRL22_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            29994..30515
                     /locus_tag="KRL22_000558"
     CDS             29994..30515
                     /locus_tag="KRL22_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH1271080.1"
                     /translation="MFSIGGGYAIIPLIQEKVVNQTGWISEKMFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIISGILGIFFYL"
     gene            complement(30644..30880)
                     /locus_tag="KRL22_000559"
     CDS             complement(30644..30880)
                     /locus_tag="KRL22_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271081.1"
                     /translation="MLECFIAEDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSEKFCQEAYDWFIENQ"
     gene            complement(31190..34618)
                     /gene="uvrA"
                     /locus_tag="KRL22_000560"
     CDS             complement(31190..34618)
                     /gene="uvrA"
                     /locus_tag="KRL22_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1271082.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLKKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCQQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKTGSQNKTIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            34937..37171
                     /locus_tag="KRL22_000561"
     CDS             34937..37171
                     /locus_tag="KRL22_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1271083.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEP
                     WAQKMLEDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            37427..39457
                     /locus_tag="KRL22_000562"
     CDS             37427..39457
                     /locus_tag="KRL22_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1271084.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVYINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IAIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            39454..39906
                     /locus_tag="KRL22_000563"
     CDS             39454..39906
                     /locus_tag="KRL22_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1271085.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            39908..40963
                     /locus_tag="KRL22_000564"
     CDS             39908..40963
                     /locus_tag="KRL22_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBH1271086.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            41030..41338
                     /locus_tag="KRL22_000565"
     CDS             41030..41338
                     /locus_tag="KRL22_000565"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBH1271087.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            41442..42707
                     /locus_tag="KRL22_000566"
     CDS             41442..42707
                     /locus_tag="KRL22_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HBH1271088.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            42795..43562
                     /locus_tag="KRL22_000567"
     CDS             42795..43562
                     /locus_tag="KRL22_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1271089.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDKVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSKKMLIIELYKIINNNYIKLYV"
     gene            complement(43690..43983)
                     /locus_tag="KRL22_000568"
     CDS             complement(43690..43983)
                     /locus_tag="KRL22_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HBH1271090.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(43989..44204)
                     /locus_tag="KRL22_000569"
     CDS             complement(43989..44204)
                     /locus_tag="KRL22_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271091.1"
                     /translation="MRILSETEKISLAAIIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            44652..45050
                     /gene="tnpA"
                     /locus_tag="KRL22_000570"
     CDS             44652..45050
                     /gene="tnpA"
                     /locus_tag="KRL22_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBH1271092.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
     gene            45047..46210
                     /locus_tag="KRL22_000571"
     CDS             45047..46210
                     /locus_tag="KRL22_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1271093.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNEGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            complement(46594..47106)
                     /locus_tag="KRL22_000572"
     CDS             complement(46594..47106)
                     /locus_tag="KRL22_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1271094.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKELSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQILLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            47556..48032
                     /gene="purE"
                     /locus_tag="KRL22_000573"
     CDS             47556..48032
                     /gene="purE"
                     /locus_tag="KRL22_000573"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBH1271095.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            48038..48736
                     /locus_tag="KRL22_000574"
     CDS             48038..48736
                     /locus_tag="KRL22_000574"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH1271096.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            48748..50115
                     /gene="purF"
                     /locus_tag="KRL22_000575"
     CDS             48748..50115
                     /gene="purF"
                     /locus_tag="KRL22_000575"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBH1271097.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            50109..51185
                     /locus_tag="KRL22_000576"
     CDS             50109..51185
                     /locus_tag="KRL22_000576"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBH1271098.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVSGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNADYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            51179..51772
                     /locus_tag="KRL22_000577"
     CDS             51179..51772
                     /locus_tag="KRL22_000577"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBH1271099.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGI
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            51765..53297
                     /gene="purH"
                     /locus_tag="KRL22_000578"
     CDS             51765..53297
                     /gene="purH"
                     /locus_tag="KRL22_000578"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBH1271100.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKNHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            53308..54558
                     /gene="purD"
                     /locus_tag="KRL22_000579"
     CDS             53308..54558
                     /gene="purD"
                     /locus_tag="KRL22_000579"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBH1271101.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            54583..58389
                     /locus_tag="KRL22_000580"
     CDS             54583..58389
                     /locus_tag="KRL22_000580"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBH1271102.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLKTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKEQKIFES
                     GVKYFR"
     gene            58835..59503
                     /locus_tag="KRL22_000581"
     CDS             58835..59503
                     /locus_tag="KRL22_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HBH1271103.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCGYNNSSGFDMIMMTLLK
                     ALSQNNQQTSNGYNLSSNSEKLFNELDSVANNTVGKFIEVDTKDKSVKLRIENAVEQA
                     SKKYNVDANLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTNPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMRSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            59512..59940
                     /locus_tag="KRL22_000582"
     CDS             59512..59940
                     /locus_tag="KRL22_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HBH1271104.1"
                     /translation="MGINIDKLNISPSRSIEVKKTKENNKFSDSLNFVKQSSSLEDIK
                     RNLDGVKKAGERLVLTQNYGDISRYKNAVKEYLKSVVDNMYSLDKSSSFWEHQYYKNV
                     KIIDNKLEDMTSKLLSEEKENIDIVSTVDMIQGLLIDMYR"
     gene            59964..60278
                     /locus_tag="KRL22_000583"
     CDS             59964..60278
                     /locus_tag="KRL22_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH1271105.1"
                     /translation="MNSKKEDIYELNFGQLIEEKTGIIDENQNVFNAKVNVAVSIGNI
                     TETIKNILDLKEGSIIKLNKNVDEKLDIYANDRLFAYGESIITNETLSVRLSKIEDSD
                     VN"
     gene            60429..60704
                     /gene="flgM"
                     /locus_tag="KRL22_000584"
     CDS             60429..60704
                     /gene="flgM"
                     /locus_tag="KRL22_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HBH1271106.1"
                     /translation="MNIKSVSSNIVVNNYLKNKSDVKKVQQVQKVDKTDKIELSKFAK
                     EMSSVSNMSDEAARNKKIEEIKSALENGTYKIKPEEIAKKMIEEMRG"
     gene            60709..61125
                     /locus_tag="KRL22_000585"
     CDS             60709..61125
                     /locus_tag="KRL22_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HBH1271107.1"
                     /translation="MITDLKVIIYEEKKIISNMMELLKEQFDYIIEKDLENLNRLNPK
                     LEDISRELASIEIKRRQLLGDDVSISEVVENSNDEYLKEIYIDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPVDKQTTTYNSYGNIRK"
     gene            61143..62453
                     /gene="flgK"
                     /locus_tag="KRL22_000586"
     CDS             61143..62453
                     /gene="flgK"
                     /locus_tag="KRL22_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBH1271108.1"
                     /translation="MAGLFSILNTANSGMNAHQKSIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIGRGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGNTVSKYDYY
                     NTIETIPNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKGDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDLENSDVKNMLSDGKLELNELKNADGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNSSAGITVRDFFITSNVAGEDIIKVNPAIKSNSNELKLTTEEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESVGLDSQKVNQDEVNQRKIINNVDNSR
                     MSVSGVSLDEEMTELMKVQRSYQASAKVMSTAVQLLDVVINGII"
     gene            62472..63404
                     /gene="flgL"
                     /locus_tag="KRL22_000587"
     CDS             62472..63404
                     /gene="flgL"
                     /locus_tag="KRL22_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBH1271109.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQINTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYIENCKDTADWLETTDTSLDQLGNLLADIKKGLVSSGNGSY
                     SDDEIKTISNSTNEKMKEIANALNATHEGKYIFSGSNTGTPPVECVENADGSVSLKFN
                     TSLNLNKLNDSLSVDVAQGISVDYNVKLSSLGFDPTKTDPFEKLNNISKKLANPSDAN
                     IKELTTTCLGDMENLIDNTVNVRSIYGTKANTVDAMKEKNDEGLIQLKDVLSQNDEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            63420..63812
                     /locus_tag="KRL22_000588"
     CDS             63420..63812
                     /locus_tag="KRL22_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HBH1271110.1"
                     /translation="MMKITLKKGILGFENLKEYELLDIENEDILKEFNSTEEDCIGFI
                     VVSPFEIIKEYEIVLNQETIEKLEVKSPNDIMLLNIITVGQTLEESTVNMKAPIVINV
                     RNNCGMQIILQDEEYSIWHPLLRGDGGC"
     gene            63806..64018
                     /gene="csrA"
                     /locus_tag="KRL22_000589"
     CDS             63806..64018
                     /gene="csrA"
                     /locus_tag="KRL22_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBH1271111.1"
                     /translation="MLVISRKKDEAVLIGDNIEVKVVGVDGNNIKLAISAPNNISILR
                     KEIYEKVKNENIKATNKNIKILKSLK"
     gene            64040..64435
                     /gene="fliS"
                     /locus_tag="KRL22_000590"
     CDS             64040..64435
                     /gene="fliS"
                     /locus_tag="KRL22_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH1271112.1"
                     /translation="MYGENPYNSYKQNAIFMASKEQLLLMLVDGAVKYTKIARGAIID
                     KNTRKAHRELIRVQDIFTELMVTLDQNAGQWAKDMYRVYDFVRYELSRANIRKDVQII
                     DNVLPVIEEIKDTWHEADRKSREERSRYK"
     gene            64435..64785
                     /gene="fliS"
                     /locus_tag="KRL22_000591"
     CDS             64435..64785
                     /gene="fliS"
                     /locus_tag="KRL22_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH1271113.1"
                     /translation="MELDLNELNGLSKEELLLMLVDGTVKYTNISKVALLNKDYLKAH
                     NELVRVQNIFTELMVTLDQSVGQWAKDMYKVYEFIKHELVKADINKDIKIIDDILPIV
                     EQIRDTWHEVYNKL"
     gene            64813..66336
                     /gene="fliD"
                     /locus_tag="KRL22_000592"
     CDS             64813..66336
                     /gene="fliD"
                     /locus_tag="KRL22_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBH1271114.1"
                     /translation="MSSISPVRVTGLSGNFDMEGIIEASMIRDKEKVNKAKQDQQIVK
                     WKQEIYRDIIKESKNLYDKYLNGDSPNSITNKKAYSATRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKVTIKLNSSDPIVQQFPPNASGASSLNIGGVNIPISEQDTTSTI
                     VSKINSLCADNDIRASYSEMTGELIISRKQTGSSSDIDLKVIGNDSLAGQIASDNGIT
                     FTTDASGTKSAVVYGKNLEADVTDDQGRVTHISKEQNSFKIDNIDYNVNSKGSAKLVS
                     VTDTEEATKNMKAFVDDYNALMDKVYGLVTTKKSKDYPPLTDEQKDDMTTEEIEKWEK
                     KAKEGILRNDDELRAFVEDIQSMFFGDADTIIALRKLGISEHENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKKIVFEYSGSSASKLTKKAGMENSSSA
                     SQNVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNKYSSQMNYFSQAQGN"
     gene            66339..66674
                     /locus_tag="KRL22_000593"
     CDS             66339..66674
                     /locus_tag="KRL22_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HBH1271115.1"
                     /translation="MDKLEEKINLYKDISLKIINFIEKMEYKNISFQLDERQNIINSI
                     SEVDKSEFIQLYDSMELFEIDANIRDALQEQLSEVKKELHEYKLTKQVNTMYYSSNRE
                     KVNIFNKKV"
     gene            66775..67647
                     /gene="fliC"
                     /locus_tag="KRL22_000594"
     CDS             66775..67647
                     /gene="fliC"
                     /locus_tag="KRL22_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin FliC"
                     /protein_id="HBH1271116.1"
                     /translation="MRVNTNVSALIANNQMGRNVNGQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGSLEETGNILQRMRTLSLQSANEIN
                     NTEEREKIADELTQLKDEIERISSSTEFNGKKLLDGTSSTIRLQVGASYGTNVSGTSN
                     NNNEIKIQLVNTASIMASAGITTASIGSMKAGGTTGTDAAKTMVSSLDAALKSLNSSR
                     AKLGAQQNRLESTQNNLNNTLENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            67741..69882
                     /locus_tag="KRL22_000595"
     CDS             67741..69882
                     /locus_tag="KRL22_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1271117.1"
                     /translation="MLLSIVMMVKNEENILEKTLKSLSVLRNSIESELIIVDTGSTDN
                     TIRIAKQYTEKVYFHNWNDDFSSMRNISISYAKGEWLLILDADEVLIDYSNIIKFFES
                     GLNKKFNSASVRLKNLYSFDKKLYGYCSVLRFFKNLDFKYCGKVHEQPMYKNPIFNNI
                     ADFEHYGYLFEDEEIRINKVKRNEKLLFEELKEDEKSPYTNYQIGKNLIILGKYQEAL
                     DYLEKSYKLYSKLEIVPGYLITNLAKVYLYLGKAKKCEKLCLKYINKDRNNIDIYYHI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEMSTQANSLLSDTDAVGFRDEAIITLIKIYY
                     KLEKYDLVISEYDNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYREIPNSKVERDSF
                     YKSMEDFINNIKDDEKELIYKSLCDIEGNYGLLNKIRINKHVSLDTCRKILNEEKDIV
                     YASVIKIAFEEKVDLLDIFYNMEYVWIEKYLRYILALERSFNVSIYKYIISCPNTSEI
                     EKIRVYKVISKILLESANLSDKKYKELFYIYIMYSYKYIKYIYSNLSDCELIKFVCND
                     IDKFTLEFKHVLDGKRKINNPNEKLEYLHNMRILLNEYPFYNRIIKIFISELEESITE
                     SEEFRLLKDNFIIRIENMIENGKINDAKLLIEDYSKTFADDVKILNIKAILFMCEDKF
                     EEADFALKKALSLDLENEDTIYNIEYLKNLK"
     gene            70584..71201
                     /locus_tag="KRL22_000596"
     CDS             70584..71201
                     /locus_tag="KRL22_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HBH1271118.1"
                     /translation="MKGNEMENYKFVFDLDSTLTKQEILPEISKCINKYELMQNLTNE
                     TMLGNLSFEESFKKRVDLLKCIPISKVKSIVAKINLNEKIVKFIKENPDRCTVVTNNL
                     DIWICDLMKELSLENKYYSSIAHSNGDFIDKIKVIIKKEDIIKKMKGPIVAVGDGSND
                     IKMIENADIGIGFGGVRPIAPGILKVCDYAFYEEERLCQLLKQLL"
     gene            71174..71818
                     /locus_tag="KRL22_000597"
     CDS             71174..71818
                     /locus_tag="KRL22_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HBH1271119.1"
                     /translation="MPTTKTIVVNCAGRGSRLGLNSNKSLIDIDGKPLIIRQLECLDD
                     YDDIRIVVGFQAEKLIEVVCSYRKDIMFVFNHDYLNTKTAASLSLGKKYSRDTVISLD
                     GDILFFKEDFDNFVNTDGEIIGVCQPYTKDPVYVKTDFINDGEFATEFSRTNGDYEWT
                     GLFKIYSKNLSSGTNHVYKMISPNLPLKIAHVELREIDTPEEYNEALKWYRNKK"
     gene            71831..72571
                     /locus_tag="KRL22_000598"
     CDS             71831..72571
                     /locus_tag="KRL22_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1271120.1"
                     /translation="MGNATRIYEKHVDIKKDTVQDFWNKRAKKHIPENPYISVKCNDQ
                     NPDYAKNLDKYEKEIIIPKLNITRNSNILDIGCGVGRLADDIVPICNYYLGTDFAEDL
                     ISIAKKRFSDNDCDFQACDFINTLYDTKVKSKMPFDTILLAGVTMYINDDELKIALKN
                     LLGILDKKATIYISIPIGINKRLTLKEFYSKELNSEYNVIYRTIEEYEEILKPLLDEG
                     FEIVESKSFLTDINQYSDTERHYFILKR"
     gene            72609..74084
                     /locus_tag="KRL22_000599"
     CDS             72609..74084
                     /locus_tag="KRL22_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol--glycerophosphate
                     glycerophosphotransferase"
                     /protein_id="HBH1271121.1"
                     /translation="MNYNKKNEVLNLIQILIEGIDYIKNNNLSESIVNSSLEAINYMK
                     KYINNSGRSNKNLLNLIDETYVKILRLSMYKNIRLIEDCELIISNLNYLSNIIENSLN
                     KKTKIVFMPYNAKMWNSLESIWKSAVLDEQCDCYVVPIPYYKLIDTPNGITQIYTYEG
                     NDFPEDVPVIHYDDFDLSKEKPDIIYVHNQYDDCNNATMVDSNYFSYNLKQYTNMLVY
                     VAYGILGTYPVSFYLNFYELIASRNFDKVIVQSPAFEIIAECSGINKNQILTMGSPKF
                     DSLIYNLKQKNINKNYESKLKGKIIFLWTTNLMKIPNGKDGVIDEIENVFDIIENSQE
                     YGLIYRPHPLELEYVKSKVPECFNRYKTLLDSISIKNNIILDDSVSYYESFNLSHALI
                     TDRSSVLIEYIQTKKPILIYDIDMERGYYDSRIFDIFSNYVVGEEDMDLIKFMNLVKN
                     NNDYKLNQRLNSLNSVLSNTDGSCGEKIHTNVLEYVLNNHI"
BASE COUNT        29493 a         7918 c        13146 g        23892 t
ORIGIN      
        1 tttatatttt gtttagggta tggtaaatcg tggtattaaa taagtagatt ttaatagtta
       61 aattatagtc aattataata aagctattta atctactttt ttaatataaa aatataaggg
      121 ggaatttgta atggcttgta acacttgtaa aatgtgcgaa agtgcagaca agaaattaga
      181 aagttttgta gcttcaaagg atgttgaaac agcatttcat agaacagaag atcagaaagt
      241 taagtgtggt tttggacttc agggggtttg ttgtagactc tgttcaaatg gaccatgtag
      301 agtaactcct aaatcaccaa gaggtatatg tggagcagat gcagacacta tagtagcaag
      361 aaacttttta agagcagtag catcaggagc agcttgttat ttacatgtgg tagaaaatac
      421 agctaagaat ttaaaaaatg ttggaataac taaaggtgtt gttaaaggag aaaaaacatt
      481 aaatcaatta gcagagatgt ttggaataga aagtgatgaa aagtatgata aatgtataaa
      541 ggttgcagac aaagttatca acgatttgta taaatcaaga gatgataaaa tggaattagt
      601 agaaaaaata gcttatgcac ctagagtgaa aaagtggaaa gagttaggta taatgcctgg
      661 tggtgcaaag tcagaagttt ttgatgcaat agtaaaatca tcaacaaatt taaatagtga
      721 cccagtagac atgctagtta attgtttgaa cttaggtata tcaacaggat tatatggtct
      781 tacactaact aatcttttaa atgatgttat gttgggagaa ccagttataa gaatggctcc
      841 tgtaggattt aatgtaatag acccagacta cataaatata atgataacag gccatcaaca
      901 ttcaacattt gcaaatttcc aagatagatt aaaagatgaa gatgttataa aattagctca
      961 atctgttggt gcaaaaggct ttaagctagt aggatgtaca tgtgttggtc aagatttaca
     1021 attaagagga gaacattatc aagaagtatt tgctggacat gcaggtaaca attttacaag
     1081 tgaggctgtt ttatcaactg gagcaataga tatagttctt tcagaattta actgtactat
     1141 accagggctt gaaccaatag cagataaata taaagtaaaa atggtttgtt tagatgatgt
     1201 tgctaaaaaa gcgaatgcag aatacatagg tttagacaga agtaaattag atgaacttag
     1261 taacacttta atagaaaaag cattggagtc ttataaggag agaagaggaa gtattgaaat
     1321 agatatacca aaagaccatg gatttgaaca atctttaact ggtgtaagtg aaaagaacct
     1381 gaaagcgttt ttaggagatt catggaaacc tcttattaat ttaattgcag aaggaaaaat
     1441 taaaggtgtt gcagctgttg taggatgttc aaatatgaca gcaggaggac atgatgtaaa
     1501 tactgttgaa cttactaaag aattgattaa aaaagatata atagtactat ctgcaggatg
     1561 ttctactgga ggattagaaa atgttggtct tatgtcacct ggagcagaag aattagcagg
     1621 agaaaactta aaagaagtat gtaagacttt aggaatacca ccagtattaa actttggacc
     1681 atgtctagct ataggaagac tagaaatagt agcaacagaa ttagcagctg aacttggaat
     1741 tgacctacca caattaccat tagtgctttc agctccacaa tggttggaag aacaagcatt
     1801 agctgatgga gcgtttggtc ttgcccttgg cttacctctt catttagctt tacctccatt
     1861 tataacagga ggaaaattgg tgacagaagt attaacagaa aaattaaaag acttaacagg
     1921 aggacatgtt atagtgaatc cagaccctaa atcttcagct aatcaattag aagaaataat
     1981 aatagataga agaaaaaatt tagggttaaa ggatgtggaa tgcaatgcat agaattttta
     2041 taaataaaga tttatgtaca ggatgtaaga gctgtgtact agcatgtatg ctaaaacaca
     2101 ataaagatta tgacatgtac actcttgatt tagaaaatat agataatgat agtagagggc
     2161 atatagaatt agatagtaga cataataatc cagttccaat tctttgtaga cactgtgatg
     2221 aacctgaatg tgtattagca tgtatgagtg gtgcaatgca taaagatagt gaaagtggaa
     2281 tcgtttcata tgatgaagag aaatgtggtt catgttatat gtgtgtaatg tcttgtccat
     2341 atggattatt aaagccagat gatagaagca agcagaacat acttaaatgt gatttatgta
     2401 aagatgagga gtatcctaga tgtgtagcta attgcccaag tggagcaatt gaattacaga
     2461 aggaggaaaa tgatgaatta tgtagtgtta ggggctagtg cagctggtat aaatgcagta
     2521 aaaacattaa gagaattaga taaagattca aatatagtag taatttctaa agatgaaaac
     2581 gtatattcaa gatgtatgtt gcatcacgtt atatctgaac acagaacttt aaaacaaata
     2641 aattttgttg atgaagattt tatggagcaa aataatgtaa aatggattgc aggtaagact
     2701 gttaaaggta tagacataaa taaaaaggta gttcagacag aagacattac tgtaaattat
     2761 gataaacttt taatagctac aggtgcatct tctgctattc ctcctataaa aaatttaaga
     2821 gatggaaatt ttgtatattc tgtgagaaac atagatgata tttataaaat aaaagaaaaa
     2881 gcacaaaatt ctaaaaatgt agttataata ggtgctggtt tagttggtat agatgcatta
     2941 gtgggattat ttaaatatga gcagttaaat atttctgtag cttttatgga aaagtacatt
     3001 ttagatagac aattggatga atatacagca tcagtgtatg aaaataagtt caaagaaaaa
     3061 ggtgtaaaat tttacccaag tgcatcaata caagaaattg tattggataa cagtaaaaat
     3121 gttacaggtg ttgcattttc aaatggtgaa gttttagatg cagacatggt aattgtagct
     3181 acaggggtta aaccaaatgc tgacttttta gatggaacag gaatagaata tgatagaggt
     3241 ataataatag atgatatgtg ccaaacaaca caaaaagaca tatatgcagc aggagatgtt
     3301 gtaggtaaaa atgctatttg gcctctggca gtaaagcaag gaattgtagc tgcctataat
     3361 atggttggaa aagataagaa gatagaagat gaatttgctt ttaaaaatag tatgaatttc
     3421 atggatatac caactatttc tataggaatg aatacacctg tagatgatag ctataaagta
     3481 ttaaccagac atggaattaa tgattataaa aagtttgttt ttaaagataa tgtaatctat
     3541 ggagcagtta tacaaggaga tatttcatat gtaggtgtat taacttattt aataaaaaat
     3601 aaagttgaaa tatatgattt agaaaatagg atatttgata tatgttatgc agactttttt
     3661 aatataaaag aaaatggaga attttgttat agtgtatagt atatacgtgg agtaaggttt
     3721 ataaatacag taaatcaata aatagagtta ttctaaaata agaaaaatga caaatcttat
     3781 ttagaaatag ctctattttt tgtaattaaa tttaaattat attcaatttg taaaatatta
     3841 ttttgaacaa ttatacatat actctctagt tagaggtaaa tcatttttta tacctttagt
     3901 gaaaagtatt tgatgtatat ctataatacc agtgttgaaa gcagcagcac aagaacaaag
     3961 gtataaatcc cacattctta taaacttatc atcaaacatt tctttaatct ttggaagatt
     4021 ctcagagaaa tttttttgcc agtatagtaa ggtttttaca taatgtaatc ttagactttc
     4081 tacgtctata gtatgatatt tgtaatcact acaaatatgt atcatttctc ttaggctagg
     4141 aataactcct cctgggaaaa tatatttttt tatccaaggg tctccataag attcctgcaa
     4201 tccacttata tagtgaagta aaaacaatcc accatctttt aaaacagcat ttacgttttt
     4261 aatgaaaagt tcatagtttt ctctaccaac atgttcaagc atcccaacgc ttacaactct
     4321 atcaaacata aggtctgatt tttttaattc tctatagtcc ataagtctta cctcaagata
     4381 gtcttgaagg ttctcttctt taattcttgt gttaaattcc ttaaattgct cttcgctaag
     4441 tgtaattcca acgccgtgaa ttttatattt ttttgcagct tctattagta aaaatcccca
     4501 accacaacca atatcgagaa ggctcatacc ttcctctaaa tttagtttag ttaatatgtg
     4561 gtgaacttta ttgacttgag catcataaag agtatcatta tcatttctaa agtatgcaca
     4621 agaataacta agtgtcttat ctaaccataa gctataaaaa tcgttgccaa tgtcatagtg
     4681 ggcatgtatt tctttctttt gatgtctcat tgaatttgat gagtgcaata gatgttttac
     4741 agctgaatta tcaatattga atttgtctat ttgttttaaa agtagattta aagttaagaa
     4801 taaatctccc tcaacttcaa tgtctctatt tatgtaggct tctccaagtg ctaaagatgt
     4861 actttttaat agttcagact tgctaatatc attatttact ataactttga actgagggga
     4921 gccctctcca attagaaatt cttcctcatc tttaagccta actagaaatg gtgtttcacc
     4981 aaatctctct aaatagtctt ttaaaaaatt ttttgtaata ttcatattac cagctccttc
     5041 taatgtaaat ccagtaagtt tccctgctta aaatatatta tagtcctttt tttaaaaaag
     5101 taaaattttt tcaataaatt ttttatttaa aggaaattta ttttttataa agaaatttca
     5161 tgttgtagta tattttttgc ttataaattt tggtactgga tataatatta aactgttaat
     5221 gatataataa atttaatcta taaagtaaat aaaattttgt aataaatagt taaagctatt
     5281 ttataaggag atatatgatg gaagtatatg ctttggttgg gtcaagtggc acagggaaga
     5341 gctttaaggc tttagagttc gcatatgaaa atgatataga atatataatc gatgatggga
     5401 ttttaatata caaaaacaag gttttagctg ggatatcagc aaaacaagca aatactacta
     5461 tagaagcagt taaaagggct attttttata atctggagca tagacaagaa gttagagaag
     5521 caattaaaaa agaaaatata agaaaaattc ttattattgg gacatcaaaa aaaatggtta
     5581 atcaaattgt agagagattg tcaattggaa gggtctataa gtttataaat atacaagata
     5641 taagtactaa atatgagata gaaatagcaa aacaagctag aaaagaagga aatcatgtaa
     5701 ttcctgttcc agcagttgag ataaaaagta tggcaagtgg tcttagtata aattctttga
     5761 agagactttt tagaaaagga aataatagga atatggtagt tttagaaaaa acaattataa
     5821 gaccaacttt tagttatata ggaaagtttt atattagtgc tgatgtaatt aaacagatta
     5881 ttgaatatga agtatacaac tttggaagca ttgatagaat aaataaaatc aatatagaga
     5941 attgcaataa ttttatgaat atttttgtaa gtataaatat caatgattta gaaactataa
     6001 aaaaaattga agacatacaa cagacaataa aaaagtctat tgagaaaatg actttagtta
     6061 atgtacaaaa aatagatatt aacattcata aaattaaaaa aataaacttc ctccaatgtt
     6121 aaaaaataaa ctgagaaaat gatatactaa tttgcaataa agtgtgctat aattaaactg
     6181 taaatttagg aaatggtttt ttctaaatgg agtatacata attataacgt atttataagg
     6241 gggctttcaa atgtcaggaa aagatgtaaa tgtcttcgag atggcgcaat ctcaagtaaa
     6301 aaatgcatgt gataaattag gtatggaacc agcagtttat gaattattaa aagaacctat
     6361 gagagttata gaggtttcaa ttccagtaaa aatggatgat ggttctataa aaacttttaa
     6421 aggatttaga tcacaacata atgatgcagt agggccaaca aaaggtggaa taagattcca
     6481 tcaaaatgtt tcaagagacg aagtaaaagc tttatctata tggatgactt tcaagtgttc
     6541 tgtaacaggt ataccatatg gtggaggtaa aggtggaata atagtagatc catcaacttt
     6601 atctcaaggt gaattagaaa gattaagtag aggatacata gatggaatat ataaattaat
     6661 aggtgagaaa gttgacgttc ctgcaccaga cgtaaatact aatggtcaaa taatgtcttg
     6721 gatggttgat gagtacaata aattaactgg acaaagttct ataggtgtta taactggtaa
     6781 gccagttgaa tttggtggtt ctttaggaag aacagctgct actggatttg gtgttgctgt
     6841 tactgcaaga gaagctgctg ctaaattagg aatagatatg aaaaaagcta aaatagctgt
     6901 tcaaggtata ggaaacgttg gttcttatac agttcttaac tgtgaaaaac ttggtggtac
     6961 tgttgtagct atggctgaat ggtgtaaatc agaaggttct tatgctatat acaatgaaaa
     7021 tggtttagat ggtcaagcta tgttagatta tatgaaagaa catggtaact tattaaactt
     7081 cccaggagct aagagaatat ctttagaaga gttctgggct tcagatgttg atatagtaat
     7141 accagctgca ttagaaaact ctataactaa agaagttgct gaatctataa aagctaaatt
     7201 agtttgtgag gctgctaatg gaccaactac tccagaggct gatgaagtat ttgctgaaag
     7261 aggaatagtt cttactccag atatattaac taatgctggt ggagttacag tttcttactt
     7321 cgagtgggta caaaacttat atggatacta ctggtcagaa gaagaagtag agcaaaaaga
     7381 agaaatagct atggttaaag catttgaatc tatttggaaa atcaaagaag agtacaatgt
     7441 tacaatgaga gaagctgctt acatgcattc aattaagaaa gttgctgaag ctatgaaatt
     7501 aagaggatgg tactaagatt tactcttaat aaataatagg atataattat ttaagatata
     7561 aaggggctgt acatagtaca gcccttaaat tatgtggctt acaatgaagt aagctatttt
     7621 tgttttaact tataaagaac ttgataaatt atgtaattta gaatgtattt tttaccacca
     7681 catgattaca aattagagga gttagattga atttttagac atgaacttat gcattttaaa
     7741 agcaaagact ttcatttaaa gtatctagta ttatttttaa aaatagtata ttggtttaat
     7801 ccatttatat ataatggaaa aatatatgga tttggattgt gaattttatt gtgatgagag
     7861 agttttaaaa aattgtactg tacaacaaaa gcaagaatat gctctaacta ttgtaaattc
     7921 aatgaaaaga ggtacaaatt tttcaaataa atttgtagct ggattaaata aacaatctga
     7981 tattagaaaa agagtaataa acatgttcag tgaaaaatat aaaaatggta tcttaatggc
     8041 tttgattata agcttgtttt cttctattac attttttaaa ttcgattcaa ctagtattat
     8101 tgaagagaat gatttcttag agaggtcaag atatacgttt gaaggaaggc aagaagacgt
     8161 gtttgtaaca atagatttta tatatgcaga tgcacctata aaacttagaa aagagcatga
     8221 agaaaactgt agagtcaatg gaatagtacc aaaagattca gattcaatag aaattattcc
     8281 tagattttat aaagattgta tggatttaaa aaaataagtt agacttaata ttgatgttga
     8341 tattatgaat tttttatatt taagcaattg aaaattttat tatagattca attttatacg
     8401 tgtttaagta tgaaatttat agatagttga aataattaaa tatgattgat gcataggaat
     8461 cattactaag ctataattaa ttatagggga gtttaaataa attatgagtt acacaattat
     8521 aaaatgataa aaatagttat ctgttacaaa aaatgtatct ttttaattaa taaagataat
     8581 atgaaaactt aaaaggcaaa taaacttaaa cataaaatac tcttaaataa gataggagaa
     8641 aaatgtatgt ctaactttat tctaaatggg atttttagaa cagttatagt aagtagtcta
     8701 agcattctta tgatattgat tttcaagaaa aatgtattta aaagatttag caaaaaattt
     8761 aattattata tatggatgat agttgttatt aaattatttt taccatttac atattatact
     8821 tttacaataa atatcttgag aagtaaaaaa cacattaata ttaataacat aaatttagag
     8881 ggatttaata atgtttcaac tataagtaat aatattatat tgtacacttg gattataact
     8941 gtagtagttt atttaattta cactatattt aaatatataa aacttaaaaa tttaataaat
     9001 gacttatctt atgatgttga tgatggagag attgtaaatc tttataaaaa tatattagaa
     9061 gaatttaata taacaaaaga tataaaactc aaatactctt atgaagttga aacaccagca
     9121 ttttttaatt catgtgtgct tttgccacca catgagtata aattgaaaga gttagactgg
     9181 atttttagac atgagcttat gcattttaag agtagggacc tttatttaaa gtatgtaatc
     9241 ctgtttttaa aaacagtata ttggtttaat ccatttatat atataatgga taaacatata
     9301 gatttagatt gtgaacttta ttgtgatgaa agagttttaa aaaatcgaaa ttcagaggaa
     9361 aaaaaggatt atgctttaac aattctaaat gcaatgagaa aaggttcaaa tacttcaaat
     9421 aaatttatag ctggacttca taagcaatct gatattaaaa agagagttat gaacatgttt
     9481 aatgaaaagt acaagaatgg tatattaatg gcattaactt tatgtttatt atcttctatt
     9541 acttttttga aggttaattc aactagtatt gttaatctta atgtattgcc aaaaggaatg
     9601 gaagaaaaag atgttactaa tagtgcaatt gttacaatga tagaatttac atatgcagaa
     9661 gctcctaaaa gtatgagaga aagatataaa ataaattgtg aattcttagg tttaatacct
     9721 aaagactctg ataaaatagg tgttggtgta gaatattatg acagtctatt gaatgattaa
     9781 ataaatatta ttttaacaga tattaattat aaagttttga atagtaattt gttgagaaat
     9841 aaatatatcc ttataaaaat agatacttat ataccaagaa taaaaaatag ttaagatagt
     9901 acacaaggat atacttataa agaacttaaa taagtgaaat aaattattaa ttataaggtt
     9961 tataatttta aaaaattaga taaattcagg tgtaaaatac tataaaacac aattcggaaa
    10021 agtgtatgtt gaatttcatt taaaatggaa tttcaaagtt gctatagtaa gtagtttaag
    10081 cattcttctt atattaatct ttgagaataa tgtatttaaa aaagttagta aaaaatttaa
    10141 ctattgtata ttaatgatag ttgctattga tatattatct aaaaaaatta agtatgaaaa
    10201 gattactgct aggacaatct tttcatactt aatttttaat atttatatta tccaaaattt
    10261 tcatcttttt aacttagaat ttgagaatca ctattaggaa ataggctttg atttatgtag
    10321 ggttaaaaat ttcacagaat atctaacttt atactaaatc catcaaaaaa tatacgccat
    10381 ataaaagcgc ataaaaaaac acataaaaca atatttatgc gcactttaac ctcgaatggt
    10441 acaaaattct ttacttttac agacccatat tatataatta agtaaataat gtatatttag
    10501 gtgacatatt ggataagcta atttatttat tttattaata taataatact ataaaagtta
    10561 tataaagtgg tttacaaaaa agttacagat agagctttta ttaatgtatt gtgtattagt
    10621 attttatcct taggtacact tcacctacaa aatagaatca taagataatt atgggaaaat
    10681 tttaggaggt ttatcgtgaa gaaaaagata ttaataccag tatttgcatc agttatggca
    10741 ttatcagtaa gttcaattgt aaatgcagat gaagtaaatg attcatctca aaataaggat
    10801 gataaaacaa atactgaatt aaatttaggt gaatataaag aagtaaaata taaagttgca
    10861 aaaataaaag atggagtagc tataaagata agagaagaag gtcaagttca aaacatagct
    10921 tattctggag atgaatttac ggttttagga actcaaggag aatgggttaa ggttaaagtt
    10981 gaagatggcg aaggttggtt agctactaga tatgtagata tatctgaagg tgtaggatat
    11041 actaacgctg ataaagtaaa cttaagaaaa gataagagtg aaagttcaga agtaattgaa
    11101 gagctggaaa aaggaagttc tttattggtt ttggaagata atggagattg gttaaaagtt
    11161 aaagatgggg aaacagaagg atatgtaaaa tcatcttata tatctgataa agctcctgta
    11221 atagaagagc cacaagtaaa cccaagtatt gaccaaaatg tagattctac aaataataat
    11281 caacaaaaca atgcaaatac taatcaacaa aataataatt caaatgtgcc aacagctaac
    11341 tctaatgcag ttcaagctgt acttaacttg gcatattcta agcaaggttg tccatatgtt
    11401 tggggagcag aaggaccaaa cacttttgac tgttctggat ttacacaata tgtgtataga
    11461 aatgcagtag gaaagaatat accaagaaca tctaaagcac aatctaaata tggacaaact
    11521 gtaagtaaag caaatttaca accaggagac ttagtattct tcacaactaa tggttctggt
    11581 tctgttagtc atgttggaat atatgtaggt gggggtaata tgatacattc accatcaaca
    11641 ggaaaaacag ttagtgtaac tagtataaat tcatcatact atacagcaag atttgttaca
    11701 gcaaaaagaa tattataatc ggtttgtaat atgacaaatt gataaataca taaatatata
    11761 taaacgctct atattatatt taatttaatc atggaaacaa aaaatgatta tattttaaat
    11821 gtactataga gcgtttttgt atcactttaa atctaatcaa gattcaagtt aatatgactg
    11881 ttaaatagga gccttttcat atgatgatta tttgcgcaat cccttgacag gatagggcaa
    11941 aggtggtaag ctactaacag tacaaaaata cttttaattt tagttcagag aggctaaaaa
    12001 aggaggacga aagatgttaa aatcaagaaa tttaatccaa ccagaagact tttcaataga
    12061 agaaatagat gaaatattag acttagctca aaaaataatt gacaatccgt caaaatattc
    12121 tcgtatatgt gaaggaaaac tattagctac attattttat gaaccatcaa caagaacaag
    12181 attaagcttt gaatctgcta tgaacagatt aggaggacgt gtagtaggct tttcagagcc
    12241 aaattcatcc tctgcatcaa aaggtgaaac tctaggagat acaatgagga tagtatctgg
    12301 ttatgttgat ataatagcta tgagacatcc tcaatcaggt gcagcttcag aagcagctag
    12361 atatacggaa gtgccattta taaatgcagg agacggcaag aaccagcatc caactcaaac
    12421 acttacagac ttacttacta taaaatcatt aaaaggaact ttagaaagcc atacaatagg
    12481 attatgtggt gatttaaaat atggaagaac tgtgcattct ttggttaagg ctatggcaag
    12541 atataaaaat acaaagtttg tatttatagc gcctgaagag ttaaaaatgc cagattatat
    12601 aaaagaagct ataaagggac atgcatatta tgaaactaat aatttggatg atgttatagg
    12661 aagcttggat gttttatata tgactagagt tcaacaagaa agatttgaag ataaatcaga
    12721 gtatgaaaga cttaaaaact attatatttt aaataaagct aaattagaaa aggcatctaa
    12781 agatatgtta gtaatgcatc cattaccaag agtaaatgaa atagacatag atgtagatag
    12841 tgatgataga gctgtatatt ttaaacaagc taaatatgga atgtatgtta gaatggcttt
    12901 aataataaaa cttttaggta taaatgaaga ctaatagtta tcatataata gtaaaacaaa
    12961 ggagattttg ggatgtataa aattctggaa aatatatata taggcgaaga tatgtataga
    13021 atgaaagtaa aaggtaattt tgaaggtaaa atgggacaat tctatatgtt aagagcatgg
    13081 gatacttatc cagtactttc aagacctata agtatacatg atatagatga agaagggata
    13141 acttttcttt ataaagtagt aggagaagga actcaaattt tgagtaacct aaaggtaaat
    13201 gataatataa aattagaagg cccttatggt aatggatatg ctaaggttga tggaaaggta
    13261 gctctagtag gaggaggaat cggtgtagct ccactatatt tggttgctaa aaatataaaa
    13321 aattgtgatg catatcttgg gtttagagaa gatgttatat tagaagatga atataaacaa
    13381 gtatgtaata aagtctatac aacagtagga aatacttttg taacagatat aattgatgtt
    13441 gagaaatatg attatatatt aacatgtggt ccaactccaa tgatggaaaa attagttaag
    13501 atggtagaag gtactaaaac gagaattatg gtatctcttg aaaaccatat ggcttgtgga
    13561 gtaggtgcct gtttagtatg tacgtgtaaa actaatggag gaaataaaaa gacttgtaaa
    13621 gatggtccag tgttctgggg agaggacgtg atttttaatg ggtaatttaa gtgtgaaatt
    13681 tggaagtgta gaatttaaaa atccagtaat aatggcgtct ggaacttttg gatttggaaa
    13741 agaatataat gagatttatg atatacaaaa acttggtggt ataagtagca agggtcttac
    13801 tttaaataaa aaacctggta acaatggtat gagagttcat gagacatcat ccggtatgat
    13861 gaatagtgtt gggcttgaaa accctggagt tcaaggattt atagactatg aattaccttt
    13921 ttttagtaaa ctagacttag tcagaatagc taatgttgga ggtgggacat tagaagacta
    13981 cttattaggg gttcaaatgt taaatgacaa gcctatagac attattgaat taaatatatc
    14041 ttgcccaaat gtcaaagctg gtggaatggc ttttggtata aaaaatgaag tggcaagaga
    14101 agttgttcgt gaggtaagaa acataacgaa actgccttta gtaataaaat tatcacccaa
    14161 tgcagaagat attgtaggaa tggcaaaagt ttgtgaagaa gaaggtgctg atggagtttc
    14221 attagttaat acttttaaag caatggcaat tgatataaaa aatagaagac cagtatttga
    14281 aaatgtatat gctgggttat ctggaccagc tataaaacct atagctttga gaatggtaca
    14341 tgaagtgtgt aaaaatgtaa atatacctgt aatggggatg ggcggaataa ctaaagccac
    14401 agatgctata gagtttataa tggcaggagc tacttgtatc caagttggaa ctgcaaattt
    14461 tatgaatcct agaataggta ttgaaataat agatggaatt aatgaattta tggatagaga
    14521 aggaataaaa agtttagacg aaataagagg aattatataa ggtagaataa atagtatttt
    14581 aaagataaaa aatatagatt aaataaacaa taattttata acattaacat ggaggaaaaa
    14641 taatatgagt aaagtagatg tagtggatat attaaagaaa agtgatgcat tgttggaggg
    14701 acatttttta ttatcttcag gaaaacacag taatagatac gtacaatgtg caaaagtatt
    14761 aagatttcca gaatatgctg ctgaggtatt aagtacagtt gttgaacaaa taaaagactt
    14821 agatatagac ttagtagtag gaccagctat gggtggagta atagtttctt atgagttagg
    14881 aagacaatta ggaaaagaag ctgtatttac tgagagaaaa gacaatacaa tggagttaag
    14941 aagaggattt gaagttaaaa aaggagcaaa gataataatt gctgaagacg ttgtaactac
    15001 tggtaaatca actatggaga caaaaagagt attagaagcc ttaggtggag aagttgtagg
    15061 tgttgcatgt atagcagata gaactaatca tgatataggt atgcctatat atagtgctat
    15121 aaaacttgat attcaagttt atgaatctga tgagtgtcct ttatgtaagg aaggaaaatt
    15181 accagttgtt aagcctggaa gtagggagtt caaggaatta gggatgtaat aaaaacttaa
    15241 ttatttatag tgttacttaa aaaatgtaaa ttttttagag taaaaatttg taatataaca
    15301 tataacttaa aaataaaaag cagttagcct tataaatgaa ggttagctgt tttttttgtt
    15361 aaaaatatat ttacaaaata agagatagta gcagtacaat ataagtataa ggtaaaagta
    15421 ttatatatta gggaggggta agtatgaaaa atcaattaaa tgaaaatcat aaaaaggttg
    15481 tattttttgg agtaggtgct gtaggagcta cttttgcaga acaatttttt aactctaaat
    15541 atgattttaa aattctttgt gataatgaaa gaaagaaaag atatttagaa gaaggattta
    15601 taataaatgg aaaaaggtat gattttgatt atgtaactaa agatgagtat aaacaagagg
    15661 ctgattttat aattataggt ctaaaatata ataatttaaa agaaaatata aaagaattag
    15721 atggattagt tggaaaaaat acagttataa tgtctctgct aaatggagtt gatagcgaag
    15781 agataatagg agaaagattt ggaattgaaa aaatggtata ttcatatgtt accaatatag
    15841 atgcaaagaa aatcaataat aatattatac acactactaa tgggataatt gtatttggta
    15901 acaaagataa tagtgaagat agaaaaacta atataataac cgaagtcttt gatgatgtaa
    15961 atatagaata tactttatca aaagatattc aacgagatat gtggtggaag tacatggtta
    16021 atattggtgt aaatcaaact tcagctatac ttggtgcacc ttatggagtt tttcagagtt
    16081 ctgagcattt aagagaatta gcaaaatctg caatgaggga agttgttgct atagcacaag
    16141 caaaagacat atctcttaca gaagatgatg tggaacattc attacataga atactagaac
    16201 attcaaaaga aggaagaaca tcaatgcttc aagatgtgga agctcataga cttacagaag
    16261 tagatatgtt ttctaagaat atctgcaaac ttggaaaaaa atataacata cctactccta
    16321 taaatcagac tttcttttat atgataaaag taattgaaag tagattttaa agggtctttg
    16381 taagaaatat tgataattat tgattttaaa ttttattaat gttatatact atttaagtta
    16441 ctaaatattt ttaactcttc aatgaaaata gttgctgctt ttgataaagt tatatctttt
    16501 ggaaatatat atgagaaatg tctgttgtag ctgcttccaa gctctatgac agacagctca
    16561 ttgtttagaa caggtaagct tgtcactaga ttagagacta ttgtaattcc taaattattt
    16621 ctaacagatt ctttgacagc ataattactt ccaaaaacca tcatactttt tggaataatt
    16681 tctttaacac ttaaaaacat atctaaataa tctctggttc cagaaccatc ctccctgact
    16741 atccattttt ggttttgaag tttatcaaaa ctaaaatctt ttaataaatg actcttgtat
    16801 ggaagtgcta aaaccatctt atcttcaaaa aaatattctt gaataaatga aggggaagag
    16861 caagtgcctt caataagacc aatgtctaaa atataatcct taacatgaga agatacgatt
    16921 gatgtatttt ttataaaaac ttctacatct atgtcaggat actttttaga aaataatgct
    16981 agaaaatttg gtaaaatata ctctccaata gttaaacttg caccaatctt taagtgacca
    17041 gttatagcat ctgaaacttg gcttacatca tgataagtaa tatttaaaag atttaatatt
    17101 tctttagctc ttttgtacaa gatttgtcca ctttctgtta taaaaatggt tttttgttta
    17161 atggacctgt ttataagaac aactttaaaa taattttcta gattttttat gtgtttactt
    17221 acacttggtt gtgatagatt taaatattcc ccagctttag taaagttttt gtattcaaca
    17281 acagctacaa atgtttttaa ttcttcaaac aattttttgt ctcctttacc taatgaaatt
    17341 ttacattttt tatatacttt ctacagataa ttatactata tataataacc attaaaaaca
    17401 ttaatcatta cgatattata tatttatttt acttatggtt attacaatta tatactattg
    17461 ctatgaagaa aactatatta attataaggt aggtatatta tgttaaagaa aaaaagcagt
    17521 ttgacattaa aaactataag ggaaatatta ccagggctgt ttgtatcagt attagtaggt
    17581 tatattagta tatttatttc tattttaatt cctaaggtag gggcagcatc aatttctata
    17641 tttttaggta tgtttgtagg aaacctattt ttaaatcaaa aggtatttca aaaaggttat
    17701 aaattttcag agacagattt gttatcatat tcaatagtac tattaggagc aacactcagt
    17761 gtatctacct taatagactt aaaagtttca ggaattttat ttataatatt gcaaatgaca
    17821 ataacaataa tagctgcact ttatataggt aaaaaactag gatttgaaga aaactttaga
    17881 tttctaatgg caagtggaaa tgcagtatgt ggttcttctg caataggagc aacagttcca
    17941 gtggttaatg cgacagataa agaaaaggga attgcagtaa ctattgtaaa tgttactggt
    18001 atatttctta tgtttttact tccaataata tctcaatttt tatatagcca tgaacttgta
    18061 aaaacttcag caatgatagg tggaactttg caatcaattg gtcaggttgt agcaagtgga
    18121 gcaattgttg gagaaaatgt aaaagattta gctactattt ttaagatagt aagagtaata
    18181 tttctagttg ttgttgtatt agtatttgga catatgaaaa atcaatctaa tagggaaatt
    18241 cttgaagaag aaaaggatga gataaaaaag aaaaaagtga ctataccatg gtatgtaatt
    18301 ggattcttta taacttgtgc acttttttca atgaacatta taccacaaga agtatctgtg
    18361 ttgtgcaaag aaataagtaa caaactagaa ataatagctt tagcagcaat tggattaaag
    18421 gttaatgtaa aagatttagt gaaacaaggg aaagaagttt ctttatatgg tttatttgta
    18481 ggtacagtac aagttgtatc agctgtagtt ttaataaaaa tatttatata gcataaaaat
    18541 agtatttgta atattaattt gattaactaa aataatatga tactaataat ttataatata
    18601 aataaaaaat gaatttcgat aagtttaagt gggtataaac ttatagaaat tcatttttta
    18661 tttaaggtaa aaatttaaag taaaatatta ttttacataa taataacctt ataaattttg
    18721 aaattactta tctttgtgtt aaaataagta aaatgcacat attagagcta agtttttaag
    18781 taaataaaca aaatgaaaat ataaatatta aggagatttg gtatatgaat gtttatgaaa
    18841 aaggtaatgg agttatacta gaaggagtaa cagattttga cccagtacat atatttgagt
    18901 gtggtcaatg ttttagatgg cacaaacaag aagatggctc atacactgga gttgcaaagg
    18961 ggagaatatt aaatgtcaaa aaagagaatg ataaaatata tttaaataat actaatttaa
    19021 aggagtttaa cagcatttgg tataattact ttgatttagg aactgattat gcagaaataa
    19081 agaataagct aaaaaatatg gatgaatatt taaataaggc tactgaattt ggatggggaa
    19141 taagaatatt aagacaagat ggatgggaaa tgcttatatc atttataatt tcctctaata
    19201 ataggattcc tatgatacaa agagcgatag aaaatttatc aagaaagttt ggtaagtata
    19261 taggtgaata tgaaggcaat gaatactatg cattcccaac accagaagaa ctaaataagg
    19321 cctcacaaga ggaaataaga gcatgtcaaa caggttttag agataagtac ataaaaagta
    19381 ctacacaggc agttatagag aataatgatg aggtatctga atatacaaat ttaagtacag
    19441 aggattgtag aaaagagctt ttaaaattta atggagtagg accaaaagta tgtgattgta
    19501 ttgcattatt tggtatgcaa aaatatgatt cttttccagt tgatgtttgg gttaagagag
    19561 ttatgcaaga attttatata gatgaagaca tgagtttacc taaaatgaga acttatggaa
    19621 tcgataaatt taaagaaatg tctggatttg ctcaacagta cttattttac tatgcaagag
    19681 aactcggtat aggaaaataa attaaggggg agaaattatg ggagtaatag gaacaatatt
    19741 tctgttctat ttaattatat catatctagc tggagccata atttctgtga ttatattact
    19801 tgaaaataga gaccctgcaa aaacaatgtc ttggctattg atgtttatta tatttccagg
    19861 tgtaggttta atgatatatg ctatttcagg tagaaatatt aggaaaagaa aattatttaa
    19921 gactcaaaaa ctagctaata atataaaaga aaagaaacta tttgatacat tagaaaagat
    19981 aacagaaata gttgaattag aaaaagaatc tataaaacaa aataagcttt taagagatga
    20041 agaggatggt agttatagaa aaagggtaat aaatatgttg ttaaagactg gtatgtttcc
    20101 ctttactaaa aataataaag tggatgtatt tgtagatgga aatgaaaagt ttaaaagact
    20161 tatagaagat ataagagaag ctaaagacca tattcattta gagtacttta tcatcaaaga
    20221 tagtgaaata ggtagggtgt taaaagaaga acttataaaa aaggctaaag aaggcattaa
    20281 gataagaatt ttatatgatg atgtaggatg ctggagattt tggtttaata gaaaattttt
    20341 ccgagaaatg agggaagtag gtatagaaat tgcagcattt ttacctacaa aatttcctat
    20401 aataggaggg aaattaaact atagaaatca cagaaaaatt gttgttattg atggaataat
    20461 tggatataca ggtggaataa atataggaga tgaatattta ggcaaaaatg ataagtttgg
    20521 atattggaga gatactcata ttaggattaa gggtatttct gtatacatgc ttcaaatgac
    20581 atttctgatt gattggtatt atacgacaaa agaagtatta gtgactaaaa attatttccc
    20641 aagtgtaggg aatgttggtg aaagtatgat acaagttgtt gcgagtggtc cagacagtga
    20701 ctgggaagat attcattatg cttatttttc tgcaatatgt caggctagaa aaaatgttta
    20761 tatagaaact ccatatttta ttccagatga aagtctacta aaagctataa agagtgctgc
    20821 tcttagtgga gttgatgtga gaataatatt tcctaaaatt gcagaccaca agatagtaaa
    20881 tatagcatct tattcatatt ttgaagaaat attaagagca ggtggtaaag tttatttata
    20941 taataaagga tttatacatt ctaaagtcgt aataatagat gataaaattg cttctgcagg
    21001 tacagctaat atggatttaa gaagttttat gcttaacttt gaggtaaatg catttatcta
    21061 tgatgaagaa gttattaggg taatgacaga tgatttcttt gaggatttaa gttactgtga
    21121 agaacttaat ttggaggtat ttaagaatag aaatatcata caaaaaatca aagaatctgt
    21181 agcaagatta ttttcaccaa tattataaaa aattattaaa aaaggtattg aaaattatgt
    21241 gtgattggta tattataata attgttagca ctctattaga tagagtgata ataaataaaa
    21301 agtatatata taaatctaca tatataagta gtattaattt aaaaataact aaaaacatag
    21361 gcgaactagt ctatacttaa tattttagga ggcgtgaata atgaaaataa gaccattagc
    21421 tgacagagta gtaattaaaa aagtagaagc agaagaaaaa actgcaagtg gaatagtttt
    21481 accaggagca gctaaagagc aacctcaaat agctgaagtt gtagaagttg gaccaggtgg
    21541 aatagttgaa gggaaagaaa taaaaatgga attgacagtg ggagataagg ttatattcca
    21601 aaaatattct ggaacagaag ttaagataga aggacaagaa tacacaatac taagacagag
    21661 tgatgtatta gctgttattg aataaatata gaataaattt attaggaggg gtttaaaatg
    21721 gctaaagaaa ttaaattttc agaggaaaca agaagagctt tagaagctgg tgtaaataaa
    21781 ttagcagata cagtaaaagt aacattagga cctaaaggaa gaaatgttat attagataaa
    21841 aaatttggtt ctccacttat aactaatgat ggagtaacta tagcaaaaga gatagaacta
    21901 gaagatagat ttgaaaatat gggtgctcaa ttagttaaag aagtagcaac taaaactaat
    21961 gatgtagctg gagatggtac tacaactgct acagttttag cacaagctat aataagagaa
    22021 ggtttaaaga atgtaacagc aggggctaac ccaatacttt taagaaaagg aatacaaaaa
    22081 gcagtaacag tagcagtaga agaattaaaa aatcaatcaa gaatagtaga aacacaagag
    22141 gctatatctc aagttgcttc tatatctgct ggtgatgaag aagttggaaa attaatagca
    22201 gaagctatgg aaatagtagg taaagatgga gttataactg ttgaagagtc tcaaactatg
    22261 aatactgaat tagatgctgt tgaaggtatg cagtttgata gaggatttgt ttctgcatat
    22321 atggttacag atgtagataa aatggaagca gttttaaatg acccatatat attaattact
    22381 gataaaaaaa tatctaacat acaagaatta ttaccagttc ttgaacaaat agttcaacaa
    22441 ggtaaaaagt tattgataat agctgaagat gtagaaggtg aagcattatc tacattagta
    22501 gtaaataaat taagaggaac atttgatgta gtagcagtta aagctccagg ctttggagat
    22561 agaagaaaag aaatgcttca agatatagca atacttacag gtgctcaagt aatatcagaa
    22621 gaattaggtt atgatttaaa agaagctgat ttatctatgc taggtagagc ttcatctgtt
    22681 aaggtaacta aagaaagtac tacaatagta gatggttctg gagataaaaa agctatagaa
    22741 gatagagtaa ctcaaattaa acatcaagta gagcaaacta cttcagattt tgatagagag
    22801 aaattaatgg aaagattagc taaacttgct ggaggagtag ctgttgtaaa agttggagct
    22861 gctacagaag tagagttaaa agaaagaaag ttaagaatag aagatgctct taatgcaact
    22921 agagcagctg tagaagaagg aatagtagct ggtggaggaa ctgcttttgt tagtgttata
    22981 ccagcaatag gaacactaat tgagagttta gaaggagaag ttaaactagg tgctcaaata
    23041 gttaaaaaag cgttagaaga gccattaaga caaatagcta taaatgctgg tcttgaaggt
    23101 gctgtaattg tgcaaaatgt tgttaattct gaagcagaaa ctggatttga cgcattgaat
    23161 gaaaaatatg taaatatgat agaagctggt atagttgacc caactaaagt tagtagaagt
    23221 gctttacaaa atgctgcatc aatagcaagc actttcttaa ctactgaagc tgctgttgct
    23281 gaccttcctg aaaaagaaga tgcaggaatg ccaggaatgg gtggcggaat gcctggtatg
    23341 atgtaattta aaaaatttaa aatataaatt ttaatataaa gaactatttc gacttagatt
    23401 ttaaactcta agttgaaata gttcttttgt atatatctaa tttttgtata tctataaatt
    23461 caatacacat atttagataa tcagtatcta gtttgtaata atattttaga gtagtattgt
    23521 tattttttag gttatgattt tagatatata ttaattaagg tataattgtt gatagagaat
    23581 aaatcaaatt taaaaggatg cgataatatg gacttaagaa aattgcttga agaagttaaa
    23641 aatgaaaata ttgatataga ttttgcgtta gaaaagttaa aagatttacc ttatgaagac
    23701 cttggatatg caaatataga tcatcataga gaactaagaa atgggtatcc ggaagttatt
    23761 tattgtgaag gtaagagtga tgagcatatt ttagggatta ttgataaaat gaatcaaaaa
    23821 agttctaaca tattgggaac aaggtgcaga aaagaaactt ttctgaaaat taaagaaatc
    23881 tataatcatg ctgagtacga agaggcgtct aaaattctta agattcaaaa tcatgatata
    23941 gagaatatag gaaaaggtaa aattgtgatt gctacagggg gaacttctga tataccagta
    24001 gcagacgaag cttatcatac agctaagttt ttaggtaatg atgttgatag aatatatgat
    24061 gttggagtgg caggtataca taggctttta aataaaagac ataaaataga tagtgctaga
    24121 gtaatagtag ccgttgcagg tatggaaggt gctcttgcaa gtgtaattgg tggactggtt
    24181 gatgttccag taatagctgt tccaacttct gttggatatg gagcaaattt tggaggatta
    24241 gcagcattac tagctatgtt aaatagctgt gcatctggaa tatctgttgt aaatattgat
    24301 aatggatttg gagcaggata tttagcatca atgataaata aactgtaaat acattgatat
    24361 aaattaaaca aaactatata ataaaattta atttctatta tatttttact attaaaattg
    24421 aggagacata tatgagtgaa aaaatacttt attttgatat aataagcggt atatcagggg
    24481 atatgaccct tgcaagttta ttaaatttag gtgtgcctaa ggaaattttt ttggaggaaa
    24541 ttcataaact aagaatgagc gatgaattta atataaacat cagctcgaaa actgaaaatg
    24601 gaatagtagg tacaaaagta gaagtaatta caaaagaaaa acatacacat agaaatttag
    24661 tggatatatt tgaggttata gataaaagca ctctaaacga aaatgtaaaa tctaaagcaa
    24721 aaaaaatatt tatggtaatt ggagaagcag aagcaaaagt tcatggaact acaatagaca
    24781 agatacattt tcatgaggta ggggctatag attcaattgt agatatagta ggagcttcta
    24841 tattagttga cttactttgt gtagataaag tttgtgctag tacagtgtct gttggttcag
    24901 gatttgtaaa atgtgaacat ggaattatac ctatacctgc acctgcaact atagaaattt
    24961 taaaaggtgt gccaattaaa ttaaataatg taaatggaga atgtacaact ccaacaggag
    25021 ctgcaatcat aaaagttttg tgtgatgagt ttgtagatga gcttgaattt tctccaaagc
    25081 aaattggata tggtataggt cataagaagt ttgaagtacc aaatatactc agaactgtat
    25141 taggtgaaaa aaaaaagaag aattaattta tgaaattagt gcaaacattg atgatatgtc
    25201 ttcagaaatc tattcttatt tgtatgaaaa aatattagat gagaaagcat tagatattta
    25261 tacagagagc atttatatga agaagaatag accagcaaca aaagtatcaa ttttatgtaa
    25321 tgaatcagat ttagaaaaat ttattaaaat attactttta gaaactagta cttttggagt
    25381 gagatataat gcatataata gagaaattct agagagaaaa tttgtaaaat tagatacaaa
    25441 atatggagtg gttacagtaa aactagggta ttataaagga aaactagtca aggctactcc
    25501 agaatataat gaatgtaaaa ctatagcaaa aaatgaagat attcctataa aaaaagtgtt
    25561 tgctgatata aattttagaa taaaagaaga atttagtgaa aacttattga cataagtaat
    25621 aaattttgat aaattaatat tcagccttat taaataaaag taaacagaaa aaaatatata
    25681 aaatataaac tcactcgtat atgctcagaa atatggtctg agagtctcta ccaagatacc
    25741 gtaaatatct tgactatgag tgaaattatt ataccaaaag acctagttaa gtaaatgtgt
    25801 aggctgagtt aaactcccta tgtgttggct ataagataaa ggtattttgg aagcctgtat
    25861 agtaatttca cttttgctag aaattatgga agttactata caggtttttt gtgtaaaaag
    25921 atttaatata atttagactg tattgtgtta aaataaatat ataaaaacta tattatacaa
    25981 ggagagatgt gaatttatga aacatgaatt agtacttgta atagattttg gaggacaata
    26041 taatcagttg atagctagaa gagttagaga aaacaacgta tattgtgaaa tacttccatg
    26101 tactgcaagc atagaaagaa taaaagaaaa aaatcctaaa gggataatat ttacaggcgg
    26161 tccaaatagt gcgtatttag aagattctcc aacaatatca aaagaaatat ttgaattagg
    26221 agtaccaata cttggaatat gctatggtat tcaaataatg tctcatgtat tgggtggagt
    26281 tgtaagaaaa ggtaataaac aagaaaaaga atatggaaaa acagctataa cttatggaaa
    26341 atcatcatta tttgaaggaa taactacaaa tagtgtatgg atgagtcata cagatttaat
    26401 agaaaaagtt ccagaaggat ttactatagt tgcaaatact aatgattgtc cagtagcagc
    26461 tatggaaaat gtagaacgaa acctatatgg agttcaattc catccagagg tagaacactg
    26521 tttggaaggg gacaagatac ttacaaactt cttatataat atttgtaaag taaaaggtga
    26581 ctggactaca gattcattca tagaagataa aataaaagaa ttaaaagaaa aaataggcga
    26641 taaaaaagct ttatgtgctt taagtggagg agttgattct tctgttgctg cagttcttat
    26701 tcataaagca attggggaca acttaacttg tatatttgtt gaccatggtt tacttagaaa
    26761 aaatgaagga aatgatgtag aaagaatatt tagagagaaa tttgatataa atttaataag
    26821 agttaatgca gaagatagat tcttatctaa attaaaagga gtttctgaac cagaagctaa
    26881 gagaaaaata ataggtgaag aatttataag agtatttgaa gaagaatcaa ataaattagg
    26941 aaaaatggat ttcttagtac aaggaacaat ctatccagat gttatagaaa gtggacatgg
    27001 aaatgctgct actataaagt ctcatcataa tgttggtgga atcccagaag atgtagactt
    27061 ccaagaaatt gtagaaccat taagagagtt atttaaggat gaagttagaa aaataggatt
    27121 agagcttggt atagaagaag gattaatatt tagacatcct ttcccaggac caggtctagg
    27181 aataagagtt ataggtgatg taactaaaga aaaatgtgat atattaagag aagctgatgc
    27241 tgtttatatg gacgagctta gaaaagcagg tttatacaga gaaatatggc aagcttttgc
    27301 aacattacca gatgttaaga ctgttggagt tatgggtgat gaaagaacat atgcttattt
    27361 agttggttta agagcagtta cttcttctga tggaatgact tctgactggt ataagatgcc
    27421 ttatgatgta ctagaaagaa tttctaatag aataataaat gaagttgatg gagtaaatag
    27481 agtagtttat gatataactt ctaagcctcc tggaactatt gaatgggaat aaaatataga
    27541 atgccaaaaa tccacataaa tacaggattt gaggtctatc ttacttctat gttatactgg
    27601 tttgatacta tcaatatttg ccagtatctt atggattaat aagcaaaaaa catcctgctg
    27661 aatgataaat tcagcggggt gtttttattt tgttttagaa ctcctttgct ctgaaactcg
    27721 aagtatttaa cactgatgat tttgttatct tttagttcct tttgtgtcat gctctgaaag
    27781 acaaattgat acaataaaaa agtaatttct taatcattga tggagatatg tatttatgtt
    27841 actcttgatg gtaatttgag taatattgtt catagctttt tatattcact taattagaaa
    27901 atcatttggt ataatcataa ataaacttga tgatataata gaaaagattt ataattatta
    27961 gaagtatata aaagtatttt atgtctatga aatgtatgtc tataaaacat atagatgact
    28021 tttgtatatt aatgtatgaa tattgatatt atagaagaat tgagttgtca atgatactaa
    28081 atcaaatatt tatagaagct ggagggatta tgagaaataa aataattata ggaattactt
    28141 tttcacttgt attactaatg tctggatgtg cttcaaaaca aaccgcagaa ataaacgtat
    28201 tagcaactac tgatttacat ggagttatac cttatgagtt aacttcttat gtaaaagaag
    28261 aaagaaaaaa agataaaaat ctaactttag tagatgcagg agattttttt gatagtggag
    28321 aagtgtttgg ttctagcatg gatagttatt ttagtgctag gtataaggat attgataata
    28381 acactgagcg ttacattgag acacctattt caaaagatat gaaagaggta ggttatgatg
    28441 ttgcagttct tgggaatcat gaatttatat ccaacaataa attttatcta gataatatga
    28501 tatctgattt tgagaaacaa aaaataaata ttttatcggc aaatacgtat aaaaaaaatg
    28561 gagatagtta tacaaaacca tacataataa aaaatattaa tacacctgaa ggaaacgtaa
    28621 aactaggaat tttagggctt actataaaag aagttggtga gaggaaacag tggaaagatg
    28681 gaaaacttgt tgactctaag tctttagaac taaaagacca agagggttac aatggtgaat
    28741 tgtatatgaa tgatttagta gaagatgcta aaaagtgggt tggtataatg gaaaaagaga
    28801 agcctgacat tatagttgct gtggcacata caggtgagaa acctaagaaa cctaaaaacc
    28861 caggaaatag aatacaagac ttagctcaac aagttgatgg aattgatgct atagttgcag
    28921 gtcataatca tgttcaaatt gagcaacatg attataaaaa taaatcagga gaaaatgtta
    28981 tagttactga gccaggaaag catggggaat gtatttctaa gattaatttt aaattagaaa
    29041 aaaacaatga taaatggaat atagttgaca aatctagtaa attaattaaa tttgaaaaaa
    29101 atcaagaaag tgataaattt ggagaattta tttcttcaat taataaagta agtaaagata
    29161 agaaagaaat aagattatca gaagtaaaga ctcctgaatg ggataaaata tatgttttta
    29221 aatctggaac atctgcagat gatatatata aaacaatagg atataaatgg agaaatatat
    29281 catctccaaa gagtgatggc atggtgcaga ttgttgtaat gaataataat aagcctgtta
    29341 gctatatata tggtgaagct gaagttatgc caattaatat aaaatgtgat gaatcagagt
    29401 ataaagataa tgttgtaact atttatccta ataaaaatga taaatttaaa attgaaaaag
    29461 gtaaacaaga atatagtatt aatttaaaac atatacaata gaaactttta tcttatttaa
    29521 gtttagattg tacttaaaat aaagtgtgta ttattttaaa aattgatgat aattaaaatc
    29581 acaacattaa ggaatagtac acacttttta tgctaaaaaa tagaatgtta aaaaattaaa
    29641 cctttaaatt aaagtacatt gcttatatta tccaatatta tcttcaaagg ttgtgtaata
    29701 tttttatcct tatgtaatat tgctaacatt ttattttcca tatctatccc atctaattca
    29761 atcaatcgca attttttatg taagagtgaa tctaataata aattttctgg caaaatggtt
    29821 atacctaaca ctgcttgtgc agctttaata agtgcaaaag aattaacact ttcccaaaca
    29881 ggataagctt tttggtttga aagagataat acactgtcca aagtatcgcg aatggcactt
    29941 ccttgctcac gtaacaataa cggaaacgtg cataactgtc gtagagataa ggcttgttta
    30001 gtattggtgg tggttatgca atcatacctt taatccaaga gaaagtagta aatcaaactg
    30061 gatggataag tgagaaaatg tttacagata ttataactat ttcacaaatg acaccagggc
    30121 cactggctgt taatacttct acttttgttg gacttcaaat tggagggttt tggggagcag
    30181 ttgcagccac tttaggttgt gtattatgtg gtgtagtaat atctctattt ttatataatt
    30241 tttttcaaaa gcatcagaac tctacttata tatttgaaat attaaatggt ctaaaatcag
    30301 cttcattagg tttaattatc tcagctgcgg ctacaattat aatccttgca ttgtttggga
    30361 cgaataaagt gtacttcaat tctatatttg agatgctaaa ctggactgca ctaataatct
    30421 tttttgttac actactgata gtacgtaagt ggaaaattaa tcctattgtg attataataa
    30481 taagtggtat actgggaata tttttttatt tataagtttt tgctaagtaa aggatatcta
    30541 tttttttata tcttaaatcc aaatagccaa taaaataagg ctatttggat ttttaataaa
    30601 ttctgaaaag ataatcagaa acctatataa catttaaatt atatcactgg ttttctataa
    30661 accaatcata agcttcttgg caaaatttct cactatctat atagtaacta ttatgaacat
    30721 tattaatttc aacaagtttc tttttacatt ttagtgaatt ataatagcta tcaaaatatt
    30781 gggttttaaa atatctatca tgaagtgttt taaagacaag agtaggtatg ttgactccat
    30841 cttttatctt actatcttct gcaataaagc attctaacat tgtattaatt atctttgtac
    30901 tatttttcca aatatgagga tttttctttt caaatatttt ataaaattca ttatcataga
    30961 cttcattata acctttatat ttaggtggtt ttactgttat gtgaaaatta ggaagaaact
    31021 taaagaaaaa atataataat ttttatgttc tgttttatat attattcata ttttatcaca
    31081 gataatatac taaagttaat ttttttattg tacaactatt ataataattc ttctataata
    31141 taagacattc tataatttta tatttaagtt catgtgtatt taattgtttt tatataaaat
    31201 gtccagtaat actatttgga tttattttta tttcatcagg agttccagaa gcaacaattt
    31261 cccctccatt tattccactg tctggaccta tatcgataat ccaatcagaa gcacgtataa
    31321 cctctgtatt gtgttcaata attaaaagtg aatgctgttc atttacaagt tttctaaaag
    31381 taattaacaa attttctata tctttaaaat gaagtccagt agtaggctca tccaatatgt
    31441 acagcattcg ttttttagtt tttgtcccta attcttttgc taattttatc ctttgagatt
    31501 ctcctccact taatcctaat gtattttgtc caagctttag atatccaagt cccacttcat
    31561 ctaataagga gagttttcta tatatatcag agcaatcgct aaaaaatgtt tttgcttctg
    31621 ctacttccat gtcaagtata tctgcaattg tctttccctt gtattgtata gacagtattt
    31681 ctttttgata tctcttacct tgacattcac tacaagttac ccattggtct gccatatatt
    31741 gcagaataat ttttgtttta cctaatcctt gacagtttgg gcattgcccc tttttgctat
    31801 taaagctaaa atagctttca tccaataatt tttgttttgc ttgtggagtt tcagcaaata
    31861 gagaacgaat ttcatcaaaa atattgatat atgtagcagg tgtagaacgg ctagattttc
    31921 caataggtgt ttggtccatt aagataaaat catcaatagc atcaaatcca gtaaattcag
    31981 tataattttt atctgggata gatttttgtt tcaatttttc ttctagagca ggaagtaaac
    32041 tgtgaaatac aagagagctc ttaccagaac cactaacacc tgtaatagag cacatacagt
    32101 ttaagggaat ttctacatca atatttttta agttatttgc atggcatcct tttaagctta
    32161 accatttact tggtatagtt ttattttgtg aacctgtttt attgtatgta cttaaatatt
    32221 tacctgttat agagtttgga ttttttataa tttcttgggt tgtaccttct gcaataatga
    32281 accccccttt tgtaccagca cttgggccta catcaataat ataatcagca gacagtattg
    32341 tatctttatc gtgttccaca actataacag tattaccctt atctcttagt tcttctatca
    32401 ttttgatgat taaattatgg tctcttgggt gtaaaccaat agatggttca tctaaaatgt
    32461 aggttaagcc tactaattca cttcctagct gacttgataa tcgtactctc tgcagttctc
    32521 ctccagataa agttggagct gttctatctg ttgatatata gctaagacct acctttaata
    32581 gataactaac tcgaattttt aattctgtta agatatcatt taccaaagag agctcatttt
    32641 tttgaagttg atttggtaat tcacacaacc aattccataa ctgttctatc gtcatttttg
    32701 ttagttcagg gaagcgataa cctttgattg tagtgaatct agcctcaatg cacagcaatt
    32761 cgccaccaca tgtattgcaa ggaattttgt tcatatattg atgcaaggta ttattttcag
    32821 aactagattc tctaaaaagt ctttgaatgt ggttgattgc tcctgaagca ggtcttctaa
    32881 tctttgattc tcgtcccttt gattcaaagc taaattcata tatcttatcg tctgtaccat
    32941 ataagattgc atctataaaa tctcttggta attcattcca aggtatatct aggtctatat
    33001 ttttatcttt tgctattgca tataattcac ctaccatcca attaccattt ggctttttcc
    33061 ccctcaattt tccaaaatag taagtggctc catctaatat tgaaatagtt gggtctttta
    33121 caatcaattg aggattaact tgataggtaa aacctaatcc attacaatcg tgacaagctc
    33181 cagtatggga gttagcattg aaggttgaag tatttatctt agaaaaaata gtttgacaat
    33241 gcggacaata attttttgta ttattctttt tttctaatgg aattttacaa tatggacagt
    33301 aactttttcc gattgataca aataacattc ttaaataatc ccaaatgctt gtaagagtac
    33361 caacagtaga gcgaggattt tggcttcctt ttttctgttc gatagctata gtaggggtta
    33421 atccctgaag taaatcaaat tccggttttt gaagctgttc tgaaagtttt gctccattac
    33481 ttagattttc aaaataacgt ctttttcctt cttcataaat cgtatcgaaa gctaaagaag
    33541 attttccact accacttaca cctgtaataa cagttatttg attttttgga attgtaacct
    33601 caacatcctt taaattgttt tgccttcctc cttttaaata gatagagctt ttattatgac
    33661 aaagtgaatt tttaattgat ttatttattg attttgtaaa tttgaatttc ttttctagtt
    33721 caagaggatt gcctaattct tttatttccg aaatacctaa tatttttaac tgagaaaaga
    33781 ttgatttcaa ataatcttca ggcaattttt ctattaacaa attaaggtct tctattttta
    33841 tatttccgct tgataatatc tctgccattt catctaataa atttttttct gctcttgtta
    33901 attgattgta ttttttggaa cttaattctg tccataaatc ccatggaagc aattctaaac
    33961 caatcatatt attaaagtca tgtagaagat taccctttac agaatgccaa cctttccaat
    34021 ttttattata tccaaagtca tctggatgag catgtccttg ctgacatctt atccaggctt
    34081 ctgaaccagt taaaaaacca tctgtttttc cgacatcatg agtgtcaaaa ttaatttgaa
    34141 aataattttt ttgtatgtca tctatttgtg catctattct tatccatctc ttttttagag
    34201 tatcatagta ttctacaagc cagtggtctt cataagtaag ctcactttca aaataattag
    34261 caaaacctgc tctcattcta gcctcaaaac ctcgatatct taggagcgat acaagaagta
    34321 aagaataatc tctgcacatt ccaacaagcc tttgttttgg gtttcttgga atagttagtg
    34381 ggttagaatt tatttcaaat attcttttta acatttgagg aattgtacga agcaattcct
    34441 catcagattg ttgtttatta aaggatatac catataattt tccttggtct ccatgaatta
    34501 ctaggctttg aaccactttt aataactcaa ttggagtctt tggtaaatct tgatatttat
    34561 tttcaaattt tttaggattt gtgatgatac tttgattttt atagttattt attttcattt
    34621 atatttcacc tctctaaatg gatgatatac cctgacatgg tgtcatatgc aaggacaatt
    34681 tagatttttt ggccaaaatt taaaaataaa taaaaaatga tacagtgata aattgtaata
    34741 caaatatagt ttcaaattgc atataatata attatttaat aaaaccatta tctattgaat
    34801 gttaatgaaa tgttaagatg gcattcttga atattaagaa atagaatact ataatatagt
    34861 gtgaaggatt tttagtaaaa aaatttgtaa gtgttaatat acattaaaaa ataggtttat
    34921 aatttggagg aaaaaaatga aattatcaag gtataagaaa aatagtttag ttctgtctat
    34981 aattttatgt tcacttatta tttcaatcct tgtaattact gtttttaata ccgtaaaact
    35041 acacaatata tctaataaac aatctaaaaa ctatttaaat gatgtatcta cacagattgt
    35101 aatgaatgtt gattctaaaa tcaaatttat tttatccgac ttaagaataa tggcagattt
    35161 tattaagcaa tatgaaggtg atagtcgata tgagtattta tctaaaagaa agactagtta
    35221 taagtattat gatgttggaa taatagattt agaaggtaaa gctgagtttt taagtggaaa
    35281 aaagtttgac ttaaagaata ctgtttccta taaaaaagga attgaaggta aagaatactc
    35341 agaagtaata gagtcaatgg gttttgttct ttatagtgta cctatattta atgataatca
    35401 tgaagtatct agtattttaa taggtgtatc caataaagaa agtatgaatg agattcttaa
    35461 tatagataac tttaatggaa aaggaactat tgaaattatt aatagtaagg gaaaacctct
    35521 tttcatagga aaaaatactg aattaataaa ggaccttagc cataaatata agagttctgg
    35581 agatgaacct tgggcacaaa agatgcttga ggattttaaa aatgataaat cagggaatat
    35641 tacaataacc tcatcaaaag gtgtacaatg cttattaact tatcatccaa ttacaagagg
    35701 tttaaatgat tggcattttc ttctcatagt acctgaagat gctgtacttg gtgaacttaa
    35761 taaattaaac tcttttacaa taacaatgac atttataatt acatgtatta ttggaattat
    35821 aacattaatt ttatatatta taagaagaaa atatgtaaat caaatagaaa atattgcata
    35881 tttagatagt ataacaaatg gtataaattc aactaagttt agtatgctag tcaaaccttt
    35941 aatttcagaa tcacctgata gtacttatat gatgatagca atgaatataa aagattttaa
    36001 gctaataaat gattgtttcg gtagtgaaaa gggaaatatg acactaaaac atctttacaa
    36061 tattttgtat aaaaacattg atgaaaatga agagtttgtg tgccgtcatg atgcagacct
    36121 tttctatttg cttattaaga atagaccagt gttagaagcc ctggagttat tatataaaat
    36181 agaagctgac acaaattatt ttaataaaaa tagggaaaat ccatactttt taagactatc
    36241 agtaggtatt tacacaattg aaaatcataa tgaagattta attacaatac aagaccatgc
    36301 aaatacagca agaaaaagct ttaataaaac tcatcaaagt gatttttctt tttatagtga
    36361 tatagaaaga aaacgattaa tatctgaaaa ggaaatttca aatttaatgg aaaaagccct
    36421 tgaaaataaa gaatttttta tgtgcttaca acctaaaatt gatataaaaa gtggaaaaat
    36481 tagtggagca gagtctcttg tgcgttggaa aaattcagaa aagggcataa tttatccaag
    36541 tgattttatt cctcttttcg aaaaaagtgg atttatatgt aagttagatt tatatatact
    36601 agaagaaaca tgcaaattga tttctaagtg gataaaagaa ggtaaagaag tgttgagaat
    36661 ttctgttaat gtatcacgtc aacatctgaa tgataaattg tttttagaaa aatataagca
    36721 tatatgcaat aaatacaatg taccaacatg tctgatagat ttagaactta ctgaatctat
    36781 tttcttagaa aatccagaag ctatagatat aatagaggat attcattcta atggatttaa
    36841 atgttctata gacgattttg gatttgggta ctcatcatta gggatattaa aggattttaa
    36901 agttgatata attaagttag accgttcatt ctttgttagc aaaaataata tagaccgtgg
    36961 taaggtagtt attaagtcta ttattgaact tagcaaaagg ctaggtatga aagtaactgc
    37021 tgaaggaatt gaagaattag aacaagttga gttcctaaaa aatgtgggat gtgattatat
    37081 tcaaggttat gttttttcaa aaccattatt aatttctgac tttgaaaatt ttgcatatga
    37141 aaataataaa attaaaaata tccattatta aatgtacaag ataaaaaatt taggcaagtt
    37201 atataattaa aaatataact tgcctttttt atttatatat ttaataaaaa tatatttgca
    37261 gattttgtaa aaataatttt caaatgttgt aagttgtggc taaagcttta ttgtattatt
    37321 ctgaatatag aaagatagtt actgtcttag ataaaaactg aaacatacat aataatataa
    37381 aatttgctat attaataact ctaattattt tggaaggagg gaaaatatga taagtgggag
    37441 aatgttactc atcatgaatt ttctaaaagg aaaaaataag acaagttaca aggatattag
    37501 caaacaactt agtatagaag aaagaaaagt tagatatgat ataaataatt taaatattgt
    37561 tttgcgttca ttaaacaagt cagtaataca aaagatgaac aaaggtgtgt taattattcc
    37621 tgatgacttc caagtagtat atataaataa taacgaatat gtattttcct taactgagcg
    37681 agtatctatt atgaaaatta tatcaatgtt taaaatagat aatctaaact tagaaaaatt
    37741 aagtaaagaa tttcaggttt ctagaagttc aattaaaaat gaccttaatg ttttgtcaag
    37801 tgaattagaa agaaaccaaa taactattac ttatgataaa tcttttaaaa taagtggaga
    37861 agaagacatt atatataagc aaagattgaa catattaaaa tcgtattctt atctttttgg
    37921 taaggaaaaa tctgatttaa gtgtatttga gaagtattta gtgaatgtaa ttgaaaaaat
    37981 attcaaaggg atttatttga ttgatatata taattggtct atgaatttat tattgcaaat
    38041 gggatggact ttaaatgatg aatcttttac atggtatgtg tcgaacattt tcctttttac
    38101 atggtatata cattcagatg aaaaacatcc tttagaatct gcttcattaa gtgagccgtg
    38161 ttttgaaaat aagtttgacc aagaatttga aacaattatt caaaaaaagt tgactaagga
    38221 acaaattttt ctgttaaaga gttttgtatt ttttacaaat aaatatgcaa gtttaaacga
    38281 ggatatggat ttgattagta cagaaattat agttcaagac ctaatttaca atatgtcaga
    38341 aatattagag attagcttta aagaagatat gattctttat aaaggattac tcaatcatat
    38401 tgctccattg atagagagaa tcaagcagaa tatacagatt tatgaggaat tacttcatgt
    38461 aataccagat aaatatcaat atgtacttga agctactaag gtttctattc aaaaaaacag
    38521 agttttaagt caaataaaga atgaaaatga aacaatactt ttggcaatac attttttagg
    38581 aagtatacat agaaatgaga ggaataacta caaaaatata ttgttagttt gtggatttgg
    38641 atatggtgta attgctatgt taaaggatag tttagtaaat gattaccaga taaatatagt
    38701 agagagtatt ccatcatata agttacaaga ttataaagaa tgggaaagta ttgacttcat
    38761 tataacaaca tcaaagatag caatagactt gcctaaaaca attattgaga taaatccatt
    38821 tttacaagaa gaggattatt tgaagtttga agaaaaaggg ataaaaagaa agaacgtctt
    38881 aactaattat atgtcaataa aaaaaaggtt ggacttttta gaagaagatg cccaaaaaag
    38941 agtattaagt attatatgtc aagaacttgg atacagtgat gagagaatat tatttagaca
    39001 acttaattta agtgatttaa tagggattga taccataagg ataattgatg gagatatgaa
    39061 atgggaagat gctgtaaaat ttagttcaaa catacttgct aattgtgatt ttgtatcagc
    39121 acaatatgct gagaatatta tagatatttt aaaaaatgtg ggtttttatg ctgtaaaaga
    39181 taacgaattt gctttactac atggcaatga tagttcatta gtcaaagtaa gttcgataag
    39241 tttattaata tgtaaagaag cagttagttt tggagataaa aaggttaaaa tcatattttg
    39301 cctagcaagc agagataaaa aagagcaaat tcctgcaata attaatctaa ctaaaatggt
    39361 ttataagact aattttattg ctatgttaga aagtgcaaag acaaaagaag aagcagaagt
    39421 tttaattcat aaatatgaga aggaggtcac tgtatgaata aattagttaa tgtaaaatgt
    39481 tcatttaaaa tacatgttaa ttcaaaagaa gaagccatta tatcgttagt tgatgtagtg
    39541 tcaaaagaag gatatttaat agataaaaat caatttttaa aagatgtttt aaagagagaa
    39601 gaaacattgt cgacttatat tggacatggt ataggtcttc ctcatagtca aagtgtaggt
    39661 gttaaaaact cttgtattac aataggaaag cttgatactc ctattgaatg gacagaagaa
    39721 ggagaaaaag tggatttaat atttttgata tcagtaacaa aagacaatga aaataatctt
    39781 catttaaaga ttttatcaaa attagcacgt ttattgatgc atgaaagttt tagaaatcaa
    39841 attagatgtt cagatgaaca aactgtttat aatcttataa aagaaaaaat agaggaggaa
    39901 gattaaaatg agaattttaa agtttttgca aaaacatctt atgacagcaa catcttatat
    39961 gattccattt gtggttgcag gaggaatatt atttgcttta tcagtaactt taagtggaca
    40021 agctgctgtt cctgaaacag gctggttggc taaactgaat caaattggag ctgctggctt
    40081 ggctttattc attcctatat taggtggata tatagcattt agtatggcag ataaaccagg
    40141 attagctcca ggtatgatag gtgcatattt agcaaaagaa gtaaatgcag gttttatagg
    40201 tggtatcata gcaggattta tagcaggatt tgttgtttta caattaaaga aaattaaatt
    40261 agctcctaca atgagaactt taggttctat atttatttat cctttagttg gtacattgat
    40321 tacaggtggt ataattgtat ttttaattgg agaacctata gcttctttta tgacatggat
    40381 gacaaactgg ttaaatggaa tgtctggtgt ttctaaaatt cctttaggtg gaatcttagg
    40441 aggaatgata gcctcagata tgggtggccc tataaataag gttgctgcta cttttgccca
    40501 aactcaagtt gacacacttc catatttaat gggtggagtt ggcgttgcaa tttgtatacc
    40561 tccaattggt ttaggattag ctacattatt gtttccaaaa aaatttagca aggaagaaag
    40621 agattcaggt aaagcttcac tattaatggg atgtgttgga attacagaag gagctattcc
    40681 atttgcaaca tcagatccag ttagagtaat accttgtatt atggctgggt cgattgtagg
    40741 aaatattatg gcttttttat taggatgttt aaatcatgca ccctggggag gtctgatagt
    40801 gttacctgta gttgacaata ggttggggta tattgcatca gtattaactg gagcagtagt
    40861 tgttgcggta ttaatgaaat tagtaaaaaa agacgtgaaa gaagatgaag aaattgaaga
    40921 agatttagat gaatcaattg aattaatatt tgaagaatta taaatataaa tggaaggaat
    40981 ttgtataaaa aagtaaatat aaaactataa atttaaagga gataagaata tgaaaattgt
    41041 agcagtaaca tcttgtccta gtggagtagc acatacttac atgtcggctg aatcacttga
    41101 attatcagcc aaaaaatttg gtatagaaat aaaggttgag actcaaggaa gctctggaat
    41161 agataatgaa ttgtcactta aagatattga tgaagcaact tgtgtaatat tgactaatga
    41221 tgttgagatt agaaatatgg aacgttttaa aggaaagaag gtagtaagaa tgagtgtatc
    41281 tgagataatt aagaaatctg atgcattaat taagaaaata aaagatactt ttcaataaaa
    41341 attgatttat tttacatata actcaaagat gtttttaaag aaatttttat taaaagcatc
    41401 tttgaaaata tcttaaaaat agaataaaag gagatatagt catgaaaaag ttaccaataa
    41461 agactgtcgt gcaaagatta ctaaacttac aagaagaggg gaaaagtgca actcttttag
    41521 gaattggtcc tatgtcacca aacttgttac aagcaagttt tgaactagca aaagatgatg
    41581 attttccttt aatgtttatc gcaagtagaa atcaagtaga tgcagatgaa ctaggtggcg
    41641 gttatgtaaa tggttggaat caggaaactt ttacaaaaga tattaagaag gttgccgaca
    41701 aagttggatt tgatggttta tattatttat gtagagacca tggtgggcca tggcaaagag
    41761 ataaagagag aaatgaccat ttgcctgttg atgaagcaat ggagttagga aaaaaatctt
    41821 atttagcgga cattgaagca ggttttgacc tattgatgat tgaccctaca aaagacccat
    41881 ttgaaattgg aaaagtaatt ccactagatg tagtactaga aagaactgta gaattaattg
    41941 agtattgtga aaacgagaga aaaagactta atctaccaga cataggttat gaggttggta
    42001 cagaggaaac caatggaggt ctgacttcaa ctgagacgta tgaaacattt ataactagac
    42061 taaaggttga acttgataat agaggtttgc caatgccaac atttatagtt ggtcaaactg
    42121 gtactttaac tagaaagaca gaacaagtag gaacttttaa ttttagaaat gcttatgatt
    42181 tagctcaaat ggctaagaaa tatggagttg gtttaaaaga gcataatggc gattacttag
    42241 atgatgtaac tttattagaa catataccat ctcaaattat tgctacaaat gtagctcctc
    42301 aatatggtac tgaagaaact agggcatatt taaaattagc agaagttgag tgtaaattag
    42361 aaaaagaggg cttagttgag aaaacttcta atatcagaca tgttcttctt gttaatgcaa
    42421 ttgaatgtgg acgttggaga aaatgggtag taggagaaca aaaaaatcta actactgaag
    42481 agatatttaa ggatgaagtt ttatctaatg aaatactaga tattgcagga cattatacat
    42541 ttaataatga tgatgttaaa aaagaaatag aagtgcttta tgataattta agtaagaata
    42601 atattgatgg tcaaagattt gttgtagacc atattaaacg tcctttgcgt gattatgcag
    42661 aatgctataa cttaaaaggt gttactacga ggattttaaa taaataatag gacttatagt
    42721 ggtgagtatt attatactag gtatttatag ttataattat acttaccact attaaattta
    42781 ggaggactaa tattttgatt aatttaattt ttgatgtaga tgatacttta tataatcaat
    42841 taacgccttt ttacactgca tataataaag tgttttcttc aataaaggat atttctattg
    42901 aagatttata tatgagtagt agaaagtata gtgataaggt atttcatatg actgaaaatg
    42961 gagaaatgcc aatcaaagaa atgcatattt ataggataat gaaagctttt gaggagttgg
    43021 gaaattctat tacagaaaaa gatgcacaaa gttttcaaga tgagtatata tatcaacaat
    43081 cacaaattac actaatacca gaagttgaga ggattttaaa tttttctaaa gaaagaaata
    43141 ttaatctagg aattataact aatggcccat caaaccatca aagaatgaag ttaaagcagt
    43201 taaatattga aaactgggtt gataaaagta atatttttat ttctagtgag gttggatttt
    43261 ctaagccaga tactaatatt tttagagtag ctgagaatgt tatgaattta gatagagaaa
    43321 atacatatta tgtgggtgat tcttatagaa atgatgtatt aggtgctaaa aaagctggtt
    43381 ggaagagtat atggttgaac catagaggac atgaggtaga agaattgttt tataaacctg
    43441 attttgtaat tttggaacat aaggatttga tatctttatt tataaaaata tgtagtaaaa
    43501 aaatgttaat aatagaattg tataaaataa ttaataataa ctatataaaa ttatatgttt
    43561 agattgtgag caatctattt tatgttaaaa atagattatt tagaagaagg ggaaatctta
    43621 aaaaaatttg aatatcccct ttttattatt taattaaaat gaaatagtta gaaatatatt
    43681 ttatttagtt tagtcaataa cattttggga ttctttataa ctacatgtta actgttgaat
    43741 aggtttatca tatggtttaa cccatccttt attaatactt aattctgtaa gtgctgtgtg
    43801 accttctacc atttgagtta atgaagctga atatatagct cttaattcag gtgtactact
    43861 tgtcaatgca gaattaagat acatattggc agatgcttta gcagatgaaa gcatacttaa
    43921 cattattact ttatcgtcta tataagtatt gttcttaatt agattttcta tcatatttct
    43981 catgttatct atacctcctc agaaattagt atttcatttt caactataaa ttgttgtata
    44041 gctttaattc ttccttctgt tgctaatata ctagattctg attgtctttt taggtcttca
    44101 tctgatatta acatatttat tgctctttgc ataagtaatc cgtcagactc catttttata
    44161 attgctgcta aagatatttt ttcagtttct gaaagtattc tcatttaatc atctcctata
    44221 ttgtaattta tgctttaata gtatgtcttt cttttcaagg aaataaccat tacacttttt
    44281 tacagtattt tatattctct ttatatcaaa atttagtcga cctaatatat taatataatt
    44341 ttgtaggata tttatcatta aatatctata aaataaatta tttgaatatt cataaagcaa
    44401 aatttatttg tatgtacttc ttcaagagtc aatatgagtt ttttcaaaaa attaattttt
    44461 atgataatca ttaagggcta tatttttctt aaagttgtga ttatcattat taatttacaa
    44521 taaaattgcc gaaaagccct ctcctttagg tgtagggatg aaaggtaagg tcttaatata
    44581 aaaaaagtta gaataatgct tgtaatctaa taccgctact gataccctat atttaggagg
    44641 tgttagtttt tatgtataaa tctaacaaaa atatagttta tgattgcaaa tatcatattg
    44701 tattttgccc taagtatcgt aaacctgttt tagttggcga agttgaaaag atgttaaaag
    44761 aaatactacc atataaagca gatgaacttg gagcagaaat aatagaaatg gaaactgata
    44821 aagaacatgt gcacttatta atatcttgtg accctcaata tggaattcat aaagtagtaa
    44881 aaggtttaaa aggctttagt tcgagagtat taagagagaa ctttccacat ttaaagtcta
    44941 gtatgcctag catgtggact aatagctatt ttgtaggtac tgttggttct gtgagtttag
    45001 aagtagttaa acaatatata gaaaatcaac aagttaggac aaagaaatga taaaaactca
    45061 tagagtgaaa ttaaacctaa ctagaacaca atttgaatta gtaagggaaa agcaaatgga
    45121 aagtgctaac tgttggaact acatagttaa cttatctaaa gaatactatt ttgaacataa
    45181 acaatggatt aaaaagaatg atatacaaaa gttaatcaaa ggtaagtaca atcttcatag
    45241 tcaaactatt caagctatat cagataaatt tgatgcaaat agaaagacta tatcagaatt
    45301 aagaaaaaaa ggtaatacta aagcaaaata tccatacaag actaagaaat tttatataat
    45361 accttttaaa gctagtgcta ttaatagaaa tgctaaaggc aacttaaaat tatcaatgtc
    45421 aaaaggcagg tatttagaat tagattttaa tgttgagaat ataaaaactg ctgaaatagt
    45481 atggcgaaac ggatattatt tatactacac ttttgacaat gaattaaatg gagttgtagc
    45541 caaaggcact aataccgtag gtgtagactt aggggaaata cattcgatag ctagtgtaac
    45601 aaatgaaggt gtagggctta ttctatctaa tagagaaggc agaagtatta aacaatttag
    45661 aaataagatg tatgcttata tatctaaaag attaagtaaa tgtaaaaaag gtagtagaca
    45721 atcaaagaag ttatggagat taaaaaataa gataagaagt aaaacagata atcagttaat
    45781 gaatttatat catcaaacaa ctagaaagtt tatagacttt tgtgtagagc agaaggtatg
    45841 tgaaatagtt cttggggata taaaaggggt tgaaaaagat actaagaaaa agaaaagatt
    45901 aaacagagtt aatagacaga aaatatctca aatggagtat ggtcgaataa aggactatat
    45961 aaaatataaa gcaaaagagc aaggtattga agttaagtta gttaaagaaa actacacttc
    46021 tcaaacttgc ccaaagtgtt ctaaaaaaca caaaccaact ggtagaactt atagttgtac
    46081 ttgtggttat gaaactcata gagatatagt tggtgcttgg aatattttaa ataaaaagca
    46141 taaatatggt ttagtagatt ttagaataaa tcataagcaa ccaataaatt taaaagtatc
    46201 taccgtttga gccatgtgtg ggcgaataac tttaaggtag tagtggcgaa gacaccgtcc
    46261 gaagtagctt ggctttgtaa ccacctctgt tgtactgttt aagtataaat aagtgtgtta
    46321 gccaccaaga atccccttgc tttagctatg gggagtgtgt caataaaata ctttaatgaa
    46381 aaatagctaa ctttaattgt aggatattct taatatattt gaaataaata aaaatattga
    46441 aggatataat attcaattgg tatataaata ataaatgata gttaaatttt accttagagg
    46501 ctaattaggt gtttagtcaa agttaatgcc tttagaatac aaatgtattc taaaggcatt
    46561 tttactatgt attttcattt atattactaa acattatcta tttttatata catttctatg
    46621 tattttattt tcatcaaatc ggtctataaa ctcatttttt tcttcactat atccaataga
    46681 tataagtgca taaggaacta attttaatgg taagtctaaa gtttgtctaa ctttatttac
    46741 cactttattt ttaggaaata ctcctgccca acaagcagct agaccttgat tagtaacttc
    46801 taataataaa atttgtgtgc aagcacctaa atcttgtatc catttaccag gttttaagaa
    46861 tttatctcta tttccaagca ctactataca taatggtgca aattctatat gctttgctct
    46921 atgctgtgac tttgagagct ctttcagcag ttccttatca tctactataa taaattccca
    46981 aggttgagca ttttttgatg aaggtgcttg catagctgat tttagtattt cagttatttt
    47041 atcttcttct atatttttat ctatatatgt tcttattgaa cgtctatttt ttataacttc
    47101 taacatacag attctccttt aaataaaatt atttctattt atataatatc attactttaa
    47161 attttagcta ttacttatat aaagaataaa ctttgtgttg gttttatcta agtaaaagta
    47221 acattcagaa ctaaaaaaca agactataaa tccaaagtat taattaaaaa agaagtaata
    47281 aaaaataata tacaagattt aaaaaagagt attgggctta aaatttaatt agaaaaccaa
    47341 ttttgagata atctgttttt tattttaaca aaaaaacata aataaagttc gatacatagc
    47401 gaatgaaaaa attacaagaa atattttttt taaaaaattt caaaaaagag ttgataatat
    47461 atgtatatta atataaaatt taaggtgtat aattcgtata ataatacgaa tgatttgtag
    47521 tgtaaaataa cttataaacg gagaggggaa gtctaatgaa agtagcagta gttatgggtt
    47581 caaaatcaga ttatccaaaa ttagaagaag ggataaaact gcttgaaaaa tatggaatag
    47641 aagttgtagc aagagcatta tcagctcata gaacaccaga acaactttca atattcctaa
    47701 aagaaataga agatgatact gatgtaataa tagcagcagc aggaaaagca gcacacttac
    47761 caggtgtaat agcttcacaa acattaattc ctgtaatagg attacctatt aaatcatcaa
    47821 ctatggatgg actagactca cttttatcaa tagttcaaat gccaaaagga atcccagttg
    47881 caacagttac aatagactta ggtttaaacg cagctttatt ggcattacaa ataatgactt
    47941 taaaataccc aaaattaaaa gaggatttga aatcatatag agaagagatg gcacaaaagg
    48001 tgttagaaga cgacaagaat ttaagggggt agcagaaatg ttattatatg aaggaaaagc
    48061 aaaacaagta tattctacag ataatgaaaa tgaatatgtt gtttattata aagatgatgc
    48121 aacagcattt aatggagaaa aaaaagcaga aatatcttca aaaggtatac taaataataa
    48181 gatatcaaca ataatctttg aaatgttaaa agaaaataat ataaatactc actttataaa
    48241 aagtttatca gatagagaaa tgttagttaa aaaagtagag attttaccat tagaagtaat
    48301 agtaagaaat attgctgctg gttctatctg taaaagagtt ggtcttgaag aaggtgtagt
    48361 tttcgatgag ccaatttttg aaataagcta caaaaatgat gcttatggtg acccaatgct
    48421 aaatgatgat tatgcagtgg caatgaagtt agcaactaga gaagagttaa aattcttaag
    48481 agaagaaact ttaaaaataa acgagttact aaaagcattt ttcttaaaat taaacctaaa
    48541 gttagttgac tttaaaatag aatttggtaa ggattctgaa ggaaatataa tattggcaga
    48601 tgaagtatca ccagacactt gtagactttg ggatgtaaat acaaatgaaa agttagataa
    48661 ggacagattt agaaaagacc ttggagacct tgtagaaggt tatacggaag tactttcaag
    48721 aatgaataat aaataggagg caaatgtatg tgtggagttt tagggattta ctctaataaa
    48781 gatgtaacta aagaactata ttattcttta tattctatgc aacacagggg gcaagaaagc
    48841 tgtggtttag ctcttttaga tgatggagaa attaagtaca aaaaagatat gggattagtt
    48901 ggagatgttt ttaaggaaaa tgaattatct aagttaaaag gaaatatagg gattggacat
    48961 gttagatatt caacagctgg aggaagtcat gtttctaact gtcaaccttt agttggaagt
    49021 tgtagaaaaa gacaattagc catagctcat aatggaaatc tagttaatgc aaattattta
    49081 aaagatatgc tagaagaaga tggatatatg ttccaaacta attcagatac agaagtgatt
    49141 ttatatatac ttgctagata ttacaaaggg gatatagtag aaagtttaaa agtgacaatg
    49201 gattatataa aaggtgcata tgctcttgta ataatgagtc aagaagaatt ggttgcagtt
    49261 agagacccac atggattcag acctcttgta cttggtaaaa agggtgatga atatatattt
    49321 gcatcagaaa attgtgcaat agatatactt ggcggagaag ttataagaga tgtagagcca
    49381 ggagagataa tagtagtcaa agatggagaa ctaaaatcat atttttattc agaaaattat
    49441 aaaccagtta agaaaagttg tatatttgaa cacatatact ttgcaagaaa tgatgcaact
    49501 atagacaatg taaatgcata tgaatttaga attaaatgtg gtgagagatt agctcagaat
    49561 gaaactgtaa aggcagatat ggtagttcca gttccagatt caggttggcc aggagctatt
    49621 ggttatgcaa atgctagtgg attaaaaata agtgaaggct tagttaaaaa tagatatgta
    49681 ggaagaacat ttataaaacc tacacaagaa gaaagagaaa tagcagtaaa aataaaatta
    49741 aatcctcttt caacaataat aaaaggaaaa tctataattt tagtagacga ctcaattgta
    49801 agaggaacta catctaaaca attagtaaaa tctttaagag aagcaggagc aaaagaaatt
    49861 catcttagaa taacttctcc tccagtagct tactcttgtt actatggaat agatactcca
    49921 aatcgctcta aattaattgc atcaagtaac aacgtagaag aaatgagaga atatattgga
    49981 tgtgatagtt taaaattcct agatatagaa ggaatgttag atgcaacaga acataagtct
    50041 actttctgta aagcttgttt tgatggagaa tacccagtta agaaaattga taaggaggaa
    50101 ctactttcat gttaacatat aaagaatcag gtgtagatat agatgaagga aatagagcag
    50161 tagaccttat aaaaggtaaa ataaaaggaa cttatgatgg aaatgtagtt ggagatttag
    50221 gtaatttcag tggattatac agtttaaaag attttgtagg tatgaaagaa ccagttttgc
    50281 ttgcatctac agatggtgtt gggactaagt taaaaatagc tcagatgatg gacaagcatg
    50341 atactgttgg aatagattta gttgcaatgt gcgtgaatga tttaatttgt caaggagcaa
    50401 aaccattatt cttccttgac tatatagctc ttgggaaatt agtgcctgag catatcgaaa
    50461 aaatagttag tggaattgca gatggttgta aaatgtctgg ttgtgcacta attggtggag
    50521 aaactgctga aatgcctgga atgtatggag aagatgacta tgatttagca ggattttctg
    50581 taggaatagc agacaaagaa aagattgttt ctggaaacaa tgttaaatca ggagatgtat
    50641 tggttggtat atcttcaagt ggagtacaca gcaatggatt ttcttttata agaaagatat
    50701 ttttagaaac ttacaattat aaaatggaac aatatgttga agaactagga atgacagttg
    50761 gagaagcact tttaacacca actaaaatat atgttaaatt agctttagat gtattagcta
    50821 aacatgacat aaaagctata gctcacataa ctggtggagg gcttatagaa aatataacaa
    50881 gagttatacc taaagggtta ggactagata tcaataaaaa atcttgggag aagcctccta
    50941 tatttaaaat gatagaaggt tttaatgctg ttgatgagag agaacttcat aagagtttta
    51001 acatgggtat tgggctagtt ttaatagtag ataaagaaaa tgctgatgat gttgtaaact
    51061 ttataaataa tagagaaaat gacaatgctg attatgtaga taaaaaatat agtgaattat
    51121 tagaagataa agcttatata attggtgaag tagtagatag tcatgaaggt gtagaattat
    51181 gctaaatata ggagttttaa tatctggtgg aggaacaaat ttacaagcag ttatagatgg
    51241 tactgaatct ggagaaataa aaggtcaggt taaagtagtt atctcaagta agcaaggtgc
    51301 ttatgggata gagagagcta aaaatcataa cataaaagca atttgtgaaa ctgatgaaga
    51361 caagataata gaaattctta aggaaaataa aatagattta gtagttttgg ctggttattt
    51421 aaaaataatc agcccaaagc tggttaatga gtttagaaac aaaatgataa acatacatcc
    51481 atcattaatt ccttcatttt gtggagctgg attctatgga gaaaaagttc atcaaggtgt
    51541 tatagattac ggagctaaag taactggtgc tacagttcat tttgttgatg aaggtgctga
    51601 tactggacca atcataatgc aagatgtagt taaggtaaat caagatgatg atgcaaagac
    51661 acttgcaaaa agagtgttag aagttgaaca taggatttta aaagaaagta taagtctttt
    51721 ttgtgaaaat aaattaaaac ttcaaggtag gagagtgttt ataaatgagt aagagagctt
    51781 taataagtgt aactgacaag actggtgtag tggaatttgc taaagagtta aataaattag
    51841 attatgaaat tatatctaca ggaaatacat ttaaaacatt aaaagaaaat ggtgttaatg
    51901 taatgcaagt tgaagatgtt acaaattttc cagaaatatt agatggaaga gtaaaaacat
    51961 taaatccata tatacatggt ggtatacttt ataaaagaga taaagaatct catgtagaaa
    52021 ctgtaaatga acacaaaata cattcaatag atttagtagc tgtaaatcta tatgattttg
    52081 aaggaacttt aaaagctgga aaaaatcatg atgaaataat tgaaaatata gatattggtg
    52141 gaccatctat gatacgttct gctgccaaaa actataagga tgtaatagta gtagtagata
    52201 taaaagatta tgattctata atagaaaaat taaaaacaga tacaatgaca ttagaagaca
    52261 gaaaaaaatt atcatataaa gctttctcaa ctacaggaag atatgatgcg ttaatatcta
    52321 gttattttgc tggagaagtt ggagatacgt atcctgacat attaaattta actttccaaa
    52381 aagaacaaac tttaagatat ggagaaaatc cacatcaaaa tggtttctta tattcacagt
    52441 caaatgcaaa aaatccaatc ttaaattatg agcaattagg cggcaaagaa ctttctttta
    52501 acaacttaaa tgatttacat ggatgtttag aagtaatgag agaatttaaa gatagtgaag
    52561 aagtagtttc agtagctata aaacatgcta attcatgtgg ggtaggttta ggaaaagatg
    52621 cttttgaagc atatacaaaa tgttatgaag cggataaggt ttcaatattt ggaggaatag
    52681 taggaataac ttctactata gataaagcta cagcagagaa attaaatgaa atattcttag
    52741 aaatagtagt agcatatgat tttgaaccag aagctttaga gatacttaaa caaaagaaaa
    52801 atctaagaat attaaaatta gctaaaatag aaaatagttt acaaccatat gaaatgaaat
    52861 atttagatgg aaaattattg atacaagata gaaacaatat attagcagaa aaaagtgaaa
    52921 atgtaacaaa ggaaaaacca acagatgcac aacttaagga catggaattt ggtatgagag
    52981 tagtaaaaaa tatgaaatca aatgcaattg caatagtaaa aaatggacaa actctagctt
    53041 taggttgtgg acaaacatca agaatttggg cattaaaaaa tgctcttgaa aataacaaag
    53101 ataaagattt tacaggagct gttttagcgt cagacgcatt tttcccattt gatgattgtg
    53161 taacattagc tcatgaatat ggaatatcag cagtagttca accaggtggc tctataaaag
    53221 ataaagattc aatagaagct tgtgacaagt atgatatggt tatggtattt acaggaataa
    53281 gacacttcaa acactaagga ggatattatg aagatattgg ttgtaggcgg tggcggaaga
    53341 gagcatgcta tatgctggaa actaagcaaa gaaaaaaatg tagaaaaaat ttattgtgca
    53401 ccaggtaatg caggaattgc aaacgtagca gaatgtgtaa atataggtga tactaatata
    53461 gaagaacttt taaaatttgc caaagaaaat gaaataggtc tgacaatagt aggaccagaa
    53521 gtaccactag ttatgggaat agtagatgag tttgaaaaag aaggattaag agtatttgga
    53581 cctaataaaa aatgtgctca acttgaagga agtaaagctt tttcaaaaga atttatgata
    53641 aaacataaca tacctactgc aaaatataaa gaatatacaa acttagaaga agctatatca
    53701 gaaatagata gttttggata tccagtagta ataaaagcgg acggattagc tgctggaaaa
    53761 ggtgttgtaa tacctgaaaa tagagaagat gctatagcaa ctttaaaaga aatgatgtca
    53821 gataagaagt ttggagctgc tggagataaa atagtaattg aagagttttt aaaaggaata
    53881 gaaacttcaa ttctagcatt tgtagacaat gatacaatag ttcctatggc aagtgcaaaa
    53941 gaccataaaa aagtaaacaa ctatgagcaa ggtccaaaca ctgggggaat gggaactttt
    54001 tcacctagtg aaatatatac agaagaatta gcaaataaag taaaagagac agtattagaa
    54061 aaaactttag aaggcttcaa aaaagatgga cttaatttta aaggtatttt atttgttggt
    54121 cttatgataa ctgaagatgg agaaaaagta cttgaatata atgtaagatt tggagaccct
    54181 gagacacaat ctgttttatt tagattagaa acagatttac atgagataat ggaagctata
    54241 ctagataata agttaaaaga tatagaaata aactatagtg atgatgaagc tgtatgtgtt
    54301 atgcttacat caggagggta tccagacagt tatgaaaaag ggaaaattat aactggtctt
    54361 gaaaacttgg atgatgatat agtagtattc catagtggca ctaagatgtt tgatggtaat
    54421 ttggttacca atggaggaag agtaattggt ataactgcaa agtcaactac agttaaggat
    54481 gcagcagaaa aagtttatga aaacataaag aagataaact ttgaaggaat gcactataga
    54541 acagacatag gaagataatt tttctaaaat ggaggataag gtatgttgaa tactgaaaat
    54601 aaagactcaa tggttagaag agtattagtt gaaaaaagag aaggttttga ccttgaggct
    54661 aaagctttaa aaaaagactt agtagaaagt ttacacatag ataatataga aaatttaaga
    54721 atattaaata gatatgatgt agaaggaata tcagaagaag tttatgaaaa tgcagcaaag
    54781 acaatattct ctgaaccaaa tttagatgta gtatattatg aagaaatacc aaaattaaat
    54841 gatgaaagag tatttgcaat agaatttctt cctggtcaat acgaccaaag aggtgattgg
    54901 gcagctcaat gtgtacaaat tgtaaatcaa gggataagac ctgctattaa tacagcaaaa
    54961 gtttatatat tatcaggcaa aataactgat gaagagtttt ctaaaataaa agattactgt
    55021 ataaatccag tagatagtag agaagcatct ttagagaaac cagaaacgtt aaaaatggaa
    55081 actgaaatac caacaacagt tgaagtatta gatggattta tagatttaga tgaaaatgga
    55141 ttaaaaacat ttgtaagtga aaaaggatta gcaatgactt taggagactt acaacacgtt
    55201 caaaaatact ttaaagatac agaaaagaga aatccaacta taacagaaat aaaagtatta
    55261 gatacttatt ggtctgatca ttgtagacat actactttta tgactgaaat agaaaatgta
    55321 aagatagaag atggtaagtt taatgatata gtaaaagaag cgtatcaaat gtatcttaac
    55381 tcaagagaca atgtatatgt gaacagacat aaagatatat gtttaatgga tatagccact
    55441 gttgcagtaa aagaattaaa gaaaaatggg aaattaaatg acctagatga aagtgaagaa
    55501 ataaatgcat gtagtataaa cgtagatgtt gaagttgatg gtaagatgga aaaatatcta
    55561 gtaatgttta aaaatgaaac tcacaaccat ccaactgaaa tagaaccatt tggtggagca
    55621 gctacttgtt taggtggagc tataagagac ccattatcag gaagaagtta tgtttatcaa
    55681 gcaatgcgtg ttacaggaag tgctgaccca agaacgactt tagaagatac tttacctgga
    55741 aaacttatgc aaagaaaaat aactacagaa gctgctcatg gatatagttc atatggtaac
    55801 caaataggtc ttacaactgg gcaagttgca gaagtatatg atgaaaactt tgttgcaaag
    55861 agaatggaaa taggtgcagt tatagcagca gcaccaaaag agaatgtagt aagagaaaga
    55921 cctgaagcag gagatgtaat cgttcttctt ggaggaaaaa caggaagaga tggctgtgga
    55981 ggagcaactg gttcatctaa agaacatagt gaagagtcaa tcttaacttg tagtgcagaa
    56041 gttcaaaaag gagatgctcc taacgaaaga aaaatacaaa gattctttag aaataaagaa
    56101 gttgctcaaa tgataaaaag atgtaatgat tttggagcag gtggagtttg tgttgctata
    56161 ggagagattg ctgatagctt agatataaac ttagacttag ttcctaaaaa atatgatgga
    56221 cttgatggaa ctgagcttgc aatttcagag tcacaagagc gtatggcagt agccataaaa
    56281 aaagaaaata aagataaatt tatacaatta gcagtagaag aaaacttaga agctacgcat
    56341 gtagctacag taacagatac aggatattta agaatgttct ggaatggaaa agcaattgta
    56401 gatataaata gagagttttt agatacaaac ggagtaaaac aaactactga tgttcatgtt
    56461 actaaagtag atgaagaaaa tacattcttt agctctaatg aaatagtaaa agatgttaag
    56521 tgtgcaagta tgaaagacaa gtttacaaaa gtactatctg accttaatgt ttgttctcaa
    56581 aaaggattag tagagatgtt tgataataca attggtggta atacagtact tatgccattt
    56641 ggaggaaagt atcaagcgac tccaacacaa ggtatggttg ctaagatacc agtacttgga
    56701 ggagaaacta atacttctac aataatgact tatggataca atccaaaggt aggaaaatgg
    56761 agcccattcc atggtgcctt gtatgcagta gtagaatctg tgtgtaaatt ggttgctatt
    56821 ggaggaaatt atagtacaac aagacttaca ttccaagagt attttgaaaa acttggtaac
    56881 aatccagaaa aatggggtaa accattctca gcacttttag gcgcatttta tgcacaaagt
    56941 aaatttgaga tacctgctat aggtggaaaa gacagtatgt ctggtacatt taaagatatt
    57001 gaagttccac caacattagt ttcatttgct gttgacacag tagatgcgaa gaaagtagta
    57061 tctccagaat ttaaaaaagc agactcaaaa gtagtaatgt tatgtgtaaa caaggcagaa
    57121 aatgatgttg tagattttga ggaattaaag agaaacttag ataaagtaag agaacttata
    57181 catggaaata aagttttatc aacatatgca ttaggatttg caggtgtagg tgaagcaata
    57241 agtaaaatgg cttttggtaa taaaatagga tttaagttta gtgaagaggc tgaaaaagca
    57301 tttacagatg ataaattatt tgaggctagt tatggaaata tagtacttga attagcaaat
    57361 gatgatttaa gtatgttaga aggatacaat tatgttgtgc ttggaagtac agttaaagaa
    57421 gctagtatat ttatcaaagg tgaagaactt gcattagatg aattatataa agcacattgt
    57481 agtactttag agcctatttt cccaactaaa acagaagaag taaaatcaaa gatagaaact
    57541 ataagttata tatcacaagg agaagctaaa aaatcatcat taagtatagc tactccaaga
    57601 gtatttatac cagcattccc tggaacaaac tgtgaatatg actctgcaag agcatttgaa
    57661 agagcaggag ctaatgcaag tataagagta tttaagaatt taacttataa agacatagaa
    57721 gattctatag atacaatagt aaacgaaata aaatcttctc aaataataat gttaccaggt
    57781 ggatttagtg ctggtgatga gccagatggt tctggtaaat ttatagctac tgtatttaga
    57841 aatcctagag tgcaagaagc tataaatgaa tttttaactc aaaaagatgg actaatgtta
    57901 ggtatctgta atggattcca agtattaatt aaattagggt tagttccata tggagaaata
    57961 agagttccaa gtgaaagtgc tccaacactt acttacaata atattggtcg ccatcaagct
    58021 aagattgcta gaactagaat ttcatctaat aaatctcctt ggttagctca aactaatgtt
    58081 ggagatattc ataatatagc aatttctcat ggagaaggta agtttgttgc cagtgaagat
    58141 gttatgagag aattaattgc taatggacaa gtagcaactc aatatgttga ctttaataat
    58201 gaagctactt atgatattga gtttaatcca aatggttcat tctatgctgt tgaaggtata
    58261 actagtgctg atggtagagt gtttggtaaa atgggacatt ctgaaagaat tggtgaggaa
    58321 gtatataaga atatcatagg ggaaaaagaa cagaagatat ttgaatctgg agttaagtat
    58381 tttagataaa actttgatgt ttaattgata gctagaatat atattttaga tatttagatt
    58441 tgaagagatg taataatgtg atgataatca tttaatatta catctctttt ttatttatat
    58501 aagaaataat agttcagctt aaattaaaat atactgtgtt ataattaatt aaagttgatt
    58561 atttattaat agtaatcata ataaaggaaa gtattaataa aagggtatgg tagtcaatta
    58621 aaaaaataat tagtaaataa ttttagtata aatatttttt ttatttatcc gataatcata
    58681 atgtagtgaa actaaatcta aagttttaat gaatataaaa gaaattaatt taacaaagta
    58741 gtctataaca agaagatttt ataggaactc aagtatcttg aattatataa ggataacttt
    58801 aaagtttata aaatttagaa aggggagttt tattttgaac gaaataagtt cactaataaa
    58861 tatactggca ttgacccaat tatctggtag taataccaca aatcaatgca actgtggata
    58921 taataattca tctggatttg atatgattat gatgacattg ttgaaagcat tatcacaaaa
    58981 taatcaacaa acctctaatg gatataattt atcatctaat tctgaaaaac tgtttaatga
    59041 acttgatagt gtagcaaata atacagttgg taagtttatt gaagttgata caaaagataa
    59101 aagtgtaaag ttgagaattg aaaatgctgt agagcaagca tcaaagaaat ataatgtaga
    59161 tgcaaatctt ataaaggcaa taattaaggt tgaatcagat tttaacccaa atactgtatc
    59221 ttctgctggt gccaagggtc ttatgcaact tatgccagaa aattgcagag atttgggagt
    59281 aacaaaccct tttaacatag aacaaaatat agatgctggt actagacata ttaaggaata
    59341 tatagatatg tttggaggta gcatagaaat gggattgatg gcatataatg gtggacctgg
    59401 tagaatgaga agtagaggcg tagaatcaat ttctgacttg tataaaatgc caaaggagac
    59461 acaaaattat atacctaaag ttatgaaata ttatagaggg taggatttac tatgggtata
    59521 aatatagaca agctaaatat aagtccaagt agaagtatag aagttaaaaa gacaaaggaa
    59581 aataataagt tttctgacag cttaaacttt gtaaaacaat cttcttcact agaagatata
    59641 aaaaggaatt tagatggtgt aaaaaaggct ggggagaggc ttgtacttac acaaaactat
    59701 ggtgacatta gtagatataa aaatgcagta aaagaatacc taaaatctgt tgtagataat
    59761 atgtattcac ttgataaaag tagtagtttc tgggagcatc aatattataa aaatgtaaag
    59821 attattgata ataaacttga ggatatgact agtaaactac ttagtgaaga aaaagaaaat
    59881 atagatattg tttctactgt tgatatgata caaggcttat tgatagatat gtatagataa
    59941 gattacataa ggagaatagt tttatgaata gcaaaaaaga agatatatat gaattgaatt
    60001 ttggtcaatt aatagaagaa aagactggga ttatagatga aaatcaaaat gtttttaatg
    60061 ctaaagtaaa tgtggctgtt tctataggaa acataacaga aacaataaaa aatatattag
    60121 atttaaaaga aggttctata ataaaactaa ataagaatgt agatgaaaaa ttagacatat
    60181 atgcaaatga cagattgttt gcttatggag aaagtattat tacaaatgaa acattatctg
    60241 taagattatc taaaatagaa gattcagacg taaattaata ctttaaaaaa tatcccctta
    60301 gattattcta tattggttta atcaaggggt atttttataa aaaatttaaa atctatttga
    60361 atcgtataaa tatttttctt ctttgagcga taattaaaat ataaggatgt aattttggag
    60421 gtgaggttat gaatattaaa agtgtaagtt caaatattgt agtaaataat tatctaaaga
    60481 acaaatcgga tgtaaaaaag gtacaacaag ttcaaaaagt tgataaaaca gacaaaatag
    60541 aactatctaa atttgcaaag gaaatgtcaa gtgtatcaaa tatgagcgat gaagcggcta
    60601 gaaataaaaa aatagaagaa ataaaaagtg cattagaaaa tggaacttac aaaattaaac
    60661 cagaagaaat tgctaaaaaa atgatagagg agatgcgagg ataaagtaat gattacagac
    60721 ttaaaagtca taatatatga agaaaaaaag ataattagta atatgatgga attactaaaa
    60781 gaacaatttg attatataat tgaaaaagac ttagaaaatt taaataggtt gaatcctaaa
    60841 ctagaagata ttagtagaga acttgcatct atagaaataa aaagaagaca acttttaggg
    60901 gatgatgttt caataagtga ggttgttgaa aacagtaatg atgaatattt aaaagaaata
    60961 tatatagact taaagcatat tcttgcttta gctaaaaatc aacaagaatc aaatgattct
    61021 ctaataaaga aagaacttat tttcacgaaa aaaatgatta atttcataaa accagttgat
    61081 aaacaaacta caacttataa ttcttatgga aacattagaa aatagatatt gggaggagaa
    61141 atatggcagg attattttcc attttaaata cagctaattc aggaatgaat gcgcaccaaa
    61201 aatcaataca gacaatttct cataatataa gtaacctaga tacagatggt tattctaggc
    61261 aaaggaccga atttgctaca aatagtccaa tgtatatgcc tagtttgagc aattcaattg
    61321 gaagaggaca attaggtact ggagtccatg taacagatgt aacaagagct agaaatagtt
    61381 tttatgatta ccaatttagg gcagaagctc ataagtatgg gaatacagtt tcaaaatatg
    61441 attattataa tactatagaa actataccaa atgaaccatc agactatgga atatctgcag
    61501 gtatagatga tttttttaaa ggatgggagt cattatcaaa ggatataaat agtgatagta
    61561 aaaaaagtct agtggtagaa aatgcatcta atttagcgac tttaataagc gaaagttata
    61621 agaagcttga caagttaaaa ggagatatag attctaatat agatactgaa ataaaacaaa
    61681 taaatgacat gttaaaaagt cttgaagact taaataaatc tattgatatt atctctggtt
    61741 ctggctctac accaaatgat ttgcttgatg aaagagatag aatattggat aacttgagtt
    61801 ttaagttaga ccttgaaaat agtgatgtta aaaatatgct ttcagatggt aaattggaac
    61861 ttaatgagtt gaaaaatgca gatggaactt ggaaaacagg tatatcagga actttacaag
    61921 gcttgtttga aatgcacggt aaaattgata catataaaag cgacttaaaa gatgtatctg
    61981 atggattagc aaaacagata aatgatgttt ataattcatc tgctggaata actgtaagag
    62041 atttttttat aacctcaaat gtagctggtg aagatattat aaaagtaaat ccagcaataa
    62101 aaagtaattc aaatgaattg aagcttacta ctgaagaagc ttcaaagatt gctaagttaa
    62161 aggatgaaaa aatagatatt ggggtagctg gtggaaaagt aagcacaata agtgaccact
    62221 acaaggcttt tgcagaatcg gtaggtttag attctcaaaa agttaatcaa gatgaagtga
    62281 atcaacgtaa aattataaat aatgttgata attcacgaat gagtgtttca ggtgtatctt
    62341 tagatgaaga aatgacagaa ctcatgaaag tacaacgttc ctatcaagct agtgcaaaag
    62401 ttatgtcaac agcagtacaa ctattggatg ttgtaataaa tgggataatt taataaaagg
    62461 aggaatttat aatgagagtt agtacaggta tgatgtccag tagttatcta aattcattgc
    62521 aagataattt gcaaagatta gacaaggtca atagacaaat caacacaacg aaagaaataa
    62581 ataaactatc agataatcca tataaggcga taaagatatt gaattcaaaa agtgaaataa
    62641 aaactatgga aacttatatt gaaaattgta aagatacagc agattggtta gaaacaactg
    62701 atacttcatt agaccaactt ggtaatttat tagcagatat aaagaagggt ttggtatcaa
    62761 gtgggaatgg ttcatattca gatgacgaaa taaaaactat tagtaattca accaatgaaa
    62821 aaatgaaaga aatagcaaat gctttaaatg caacacatga aggtaagtac atattttcag
    62881 gttcaaatac aggcacacca cctgttgagt gtgtagagaa tgctgatggc tcagtaagtt
    62941 taaagtttaa tactagctta aatcttaata aattaaatga ttctttaagt gtagatgtag
    63001 ctcaaggaat cagtgtagat tataatgtta agttgagtag tcttgggttt gatccaacaa
    63061 aaactgatcc atttgaaaag ttaaataata tatcgaagaa actggcaaat ccaagtgatg
    63121 caaatataaa agagttgaca acaacttgtt taggtgacat ggagaatcta atagataata
    63181 cagtaaatgt taggtctata tatggtacaa aggcaaacac agtagatgcc atgaaagaaa
    63241 aaaatgatga aggtttgata cagttaaagg atgttttatc gcaaaatgat gaaatagatt
    63301 atggggaaaa gcttgttcaa ttaaaggctg cagaattaac ttatcaagct tcactacaaa
    63361 caggaggaaa gttatttaat gtatctatat tagattatat atagtaaaat aacgcagata
    63421 tgatgaagat tacattaaaa aaaggaatac taggatttga aaacttaaaa gagtatgagc
    63481 ttttagatat agaaaatgaa gatattttaa aagaatttaa ttctactgaa gaagattgta
    63541 taggatttat tgttgtatca ccatttgaaa ttattaagga atatgaaata gtcctaaatc
    63601 aagaaacaat agaaaaactt gaagtaaaat ctccaaatga tattatgttg cttaatataa
    63661 tcactgttgg tcaaacactt gaagaatcaa ctgtgaacat gaaagctcct atagtaataa
    63721 atgtaagaaa taattgcgga atgcaaataa ttttacagga tgaggaatat tcaatatggc
    63781 atccattatt gagaggtgat ggtggatgct agtaatttcg agaaaaaaag atgaagcagt
    63841 acttatagga gataacatag aagtaaaagt tgtaggagtg gatggaaata acataaaatt
    63901 agctatatct gctcctaata atataagtat cttaagaaaa gaaatatatg aaaaagtaaa
    63961 aaatgaaaat ataaaagcca caaataaaaa tataaaaatc ttaaaatcat taaaataaaa
    64021 cacttggagg aagtaatata tgtacggaga aaatccttat aattcttata agcaaaatgc
    64081 tatttttatg gcgtcaaaag aacaattatt gcttatgctt gttgatggtg cagtaaaata
    64141 tacaaaaata gctagaggag ctattataga taaaaataca cgaaaagcac atagagagct
    64201 tataagagtt caagatatat ttacagaact aatggttaca ttagaccaaa atgcaggtca
    64261 atgggcgaaa gatatgtata gagtttatga ttttgtaaga tatgaacttt caagggcaaa
    64321 tatcagaaaa gatgtacaaa taatagataa tgtattacct gtaatagaag aaattaaaga
    64381 tacatggcat gaggctgata gaaaaagtag agaagaaaga agtaggtata aatgatggag
    64441 ttagatttaa atgaactaaa tgggttatca aaagaagaat tactattaat gcttgtagat
    64501 ggtacagtca agtatactaa tatatctaaa gttgcacttt taaataaaga ctatttaaaa
    64561 gcacacaatg aacttgttag agttcaaaat atatttacag aattaatggt cacattagac
    64621 caaagtgtag gacaatgggc aaaggatatg tataaagttt atgaattcat aaaacatgaa
    64681 ttagtaaagg ctgatataaa taaagatatt aaaataattg atgatatatt gccaatagta
    64741 gaacaaataa gagatacatg gcatgaagtg tataataaac tataactata atcatgatgg
    64801 ggggataaac atatgtcaag tataagtcca gtaagagtta caggcctttc aggaaatttt
    64861 gatatggaag gtataataga agctagtatg ataagagata aggaaaaagt taataaagcg
    64921 aaacaagatc aacaaatagt taaatggaaa caagaaatat acagggatat tataaaagag
    64981 tcaaagaatc tttatgacaa gtatttaaat ggagactctc ctaatagtat aacaaataaa
    65041 aaagcatatt ctgctacaag aataactagt tctgatgaaa gtattatagt agcaaaaggc
    65101 tcagctggtg cagaaaaaat aaattatcaa tttgcagttt ctcaaatggc tgaaccagca
    65161 aaagtaacta ttaagttaaa ttcaagtgac cctattgttc aacagtttcc tccaaatgct
    65221 agtggagcaa gttctttaaa tataggtggt gtaaatatac caatatctga acaagatact
    65281 acaagtacta ttgtaagtaa gataaactcc ctttgtgcag ataatgatat aagagcttct
    65341 tatagtgaga tgacaggtga attgattatc tcaagaaaac agactggttc atcatcagat
    65401 attgatttaa aagtaattgg aaatgatagt ttagctggac aaattgccag tgataatggt
    65461 attacattta caactgatgc tagtggaact aaatctgcag tagtatatgg aaaaaattta
    65521 gaagctgatg taactgatga ccaaggaaga gtaacacaca taagtaaaga acagaattca
    65581 tttaaaatag ataacattga ttataatgta aattcaaaag gaagtgctaa actggtttct
    65641 gttactgaca ctgaagaagc tactaaaaat atgaaagcat ttgtagatga ttataatgca
    65701 ttgatggata aggtttatgg attagttact actaaaaaat caaaagatta tccacctctt
    65761 acagatgaac aaaaagatga tatgacaact gaagaaatag aaaagtggga aaagaaggca
    65821 aaggaaggaa tacttagaaa tgatgatgaa ttaagagctt ttgttgaaga tattcagtct
    65881 atgttttttg gagatgcaga tactattatt gctttaagaa aactgggtat tagtgagcat
    65941 gagaattata acaaaaaagg acaaatatca tttaatgcag atactttttc gaaggctctt
    66001 atagatgata gtgacaaggt atataaaact ttagctggat attcttcaaa ttatgatgat
    66061 aagggaatgt ttgaaaaatt aaaaaaaatt gtatttgaat attctggaag ttcagcttct
    66121 aaacttacta aaaaagcagg tatggaaaat tcttcgtctg ctagtcaaaa tgtatattca
    66181 aaacaaattg cagagcaaga aagaaatata agtaggttag ttgaaaaaat gaatgataaa
    66241 gagaaaagac tttatgctaa atattcagct ttagagtctt tgttgaataa atattcttca
    66301 caaatgaact atttctcaca agcacaaggt aattaattat ggacaagtta gaagaaaaaa
    66361 taaatttata taaagatata tctttaaaaa ttataaattt tattgaaaaa atggagtata
    66421 aaaatataag ttttcaatta gatgagagac aaaacattat aaatagtata agtgaagttg
    66481 ataaaagtga atttatacaa ctttatgata gtatggagct atttgaaatt gatgctaata
    66541 taagagatgc tttgcaagaa caattatcag aagtaaaaaa agaattacat gagtacaagc
    66601 ttactaaaca ggtaaacaca atgtattata gttcaaatag agaaaaagta aatattttta
    66661 ataaaaaagt ataaagttat agattaactt gtccgataat ataaacggat agttaataca
    66721 aaagttaaaa gtagaaatga caaggatgtc aactatacta aggagggtaa aataatgaga
    66781 gttaatacaa atgtaagtgc tttgatagca aacaatcaaa tgggaagaaa cgtaaatgga
    66841 caaagtaagt ctatggagaa gttatcttct ggggttagaa tcaagagagc tgctgatgat
    66901 gctgctggac ttgcaatatc tgagaaaatg agagctcaaa taaaaggttt agaccaagca
    66961 ggaagaaacg ttcaagatgg tatatctgtt gtacaaacag cagaaggttc gttagaagaa
    67021 actggaaata tactacaaag aatgagaact ttatcattac aatctgcaaa tgaaattaat
    67081 aatactgaag aaagagaaaa gatagctgat gagttaacac aattaaaaga tgagattgaa
    67141 agaatatcaa gttcaacaga gtttaacggt aagaagctac ttgatggaac ttcttcaaca
    67201 ataagattac aagttggagc aagttatgga actaatgttt caggtacaag taataataac
    67261 aatgagataa aaattcaatt agtaaatact gcaagtataa tggcttcagc tggtataaca
    67321 actgcttcaa taggaagtat gaaggcaggt ggaactacag gaacagatgc agctaaaact
    67381 atggtatcta gcttagatgc agctcttaag agcttaaact catcaagagc aaaattagga
    67441 gcacaacaaa acagactaga atcaactcaa aacaatttaa ataatacttt agagaatgtt
    67501 acagcagcag aatcaagaat aagagataca gatgttgctt cagaaatggt taacttatct
    67561 aaaatgaata tattagttca agcatcacaa tcaatgcttg ctcaagctaa tcaacaacca
    67621 caaggagttt tacaattatt aggatagaat aaatttagta tattgaataa aaaagaaagg
    67681 ataaggcttt gctttattct tttctttttt tagaaatata gttttgaaag gaaaatatat
    67741 atgttactta gtatagttat gatggtcaaa aacgaagaaa atatacttga aaaaacttta
    67801 aaatcgttat cagtattgag aaattcaata gagagtgaac ttataatagt tgatacaggt
    67861 tctacagata atactataag aatagcaaaa caatatacag aaaaggtata ttttcataat
    67921 tggaatgatg atttttctag tatgagaaat atatctatat cctacgctaa gggcgaatgg
    67981 ttacttatat tagatgcaga tgaagtatta attgattatt caaatattat aaagtttttt
    68041 gaaagtggtc ttaataaaaa atttaactct gcctcagtac gattaaaaaa tctttattca
    68101 tttgataaaa aattatatgg atattgttca gtgttgagat ttttcaaaaa ccttgatttt
    68161 aaatactgtg ggaaagttca tgaacaacca atgtataaaa atcctatatt taataatatt
    68221 gctgattttg aacattatgg atacttgttt gaagatgaag agataagaat aaataaagta
    68281 aaaagaaatg aaaaactgtt gtttgaggaa ttaaaagaag acgagaaatc tccatataca
    68341 aattatcaaa tagggaaaaa tcttattata ttaggaaaat atcaagaagc tttagattat
    68401 ctagaaaagt cttataaatt atactcaaaa ttagaaatag tacctggata cttgataaca
    68461 aaccttgcaa aagtatattt atacttagga aaggctaaga agtgtgaaaa attatgctta
    68521 aaatatatta ataaggacag aaataatatt gatatatatt atcatattgc acaagcacaa
    68581 gttgatttag ggaagtatga aaatagtata gattcatata aaagatatat ttatttgcta
    68641 gataattatg aaatgagtac acaagcaaat agtttgcttt cagatactga tgctgtagga
    68701 tttagagacg aagctataat tacattgata aaaatttatt ataagcttga gaaatatgat
    68761 ttagtaattt cagagtatga taatattgaa gatgtggaaa aaaagaaaaa tgtgtacttt
    68821 agcttattta tgtctttata taaattaaat agatttgaag acataaaaaa ctattataga
    68881 gagattccaa attcgaaggt tgagagagat agtttttata aaagtatgga agactttata
    68941 aataatataa aagatgatga gaaagagctc atatataaaa gcctttgtga tattgaaggt
    69001 aattatggtc ttttgaataa aataagaata aacaaacatg tatcattaga tacatgtaga
    69061 aaaatactaa atgaagaaaa agacatagtt tatgcaagtg ttataaaaat agcttttgag
    69121 gaaaaagttg acttattaga cattttttac aatatggaat atgtttggat agagaaatac
    69181 ttaaggtata ttttagcttt agaaagaagt tttaatgtat caatatataa atatataatt
    69241 agttgtccta atacatcaga aatagaaaag ataagagtgt acaaagttat atctaaaatt
    69301 cttttagaaa gtgctaattt aagtgataaa aaatacaaag aactttttta tatttatata
    69361 atgtactctt ataaatacat aaaatacata tatagcaatt tgagtgattg tgaattaata
    69421 aagtttgttt gtaatgacat agataaattc actttagaat ttaagcatgt acttgatggt
    69481 aaaaggaaga taaataatcc taatgaaaaa ttagaatatc tacataatat gagaatatta
    69541 ttaaatgaat acccttttta caatagaata ataaaaatct tcataagtga attagaagaa
    69601 agtataacag aaagtgaaga atttagatta ttaaaagata actttattat tcgtatagaa
    69661 aatatgattg agaatggaaa aataaatgat gcaaagttat tgattgaaga ctactcaaaa
    69721 acatttgcag atgatgtaaa gattttaaat ataaaggcaa ttttgtttat gtgtgaagat
    69781 aaatttgaag aagctgattt tgcattaaaa aaggcattat cactagactt agaaaatgag
    69841 gatactatat ataatataga gtacttaaaa aatttaaaat aaatttaaaa ctagattatt
    69901 tggaaaataa taatatcaat aacagttaat gaaaaatata atagaagatt gaatatatac
    69961 atataaaaat actgatgtaa aatttactgg tacagcaata tatatcgata ttggcatcaa
    70021 ataaaataga atatactcaa tgattttagt atatagaaga tttaattcaa gggaaactaa
    70081 ttttatcata tttacttata ataataaaat agataagcat gttcaaaaaa taaacaacaa
    70141 aaaacaatat aaatgaaaat tatacatatt ttctcttaat tttttttaaa attagacgat
    70201 aatatgtata taattaaatc gggcaatatc ctaaaaacga aggttttgca cattaagaca
    70261 attttttagt gatttcaatg attttagtgt ttttaaataa ttgaattaat tcgacataaa
    70321 acagcagtat ttgtaataat tgaattttta ttaagtcatt ttaatactta aaaaccattt
    70381 atagagtatt tttgttagtt aagaacgcaa gatttcttta ttttgataag atttagtttt
    70441 tagctttttg attgagctat atacaatttt ataataaaaa ataaaattat attataaaat
    70501 tataaactct gtaaaattat tgaaatttct aactcaatat tgtttgatgt acttatcact
    70561 caaaaatagg attttatgct tcaatgaaag ggaatgaaat ggaaaattat aaatttgttt
    70621 ttgatttaga ttcaacatta actaaacaag aaatacttcc tgagatttct aagtgtataa
    70681 ataaatatga acttatgcaa aatcttacaa atgaaactat gctaggaaat ttatcttttg
    70741 aggaaagttt taagaaaaga gtcgatttat taaaatgtat tcctatttct aaagttaaaa
    70801 gtatagttgc taagattaat cttaatgaaa aaattgtaaa gtttataaaa gaaaatccag
    70861 atagatgtac tgttgtgaca aataatttag atatttggat ttgtgattta atgaaagagc
    70921 tttctttaga aaataaatac tattcatcta tagctcattc aaatggtgat ttcattgata
    70981 aaattaaagt tataataaaa aaagaagata ttataaaaaa aatgaaaggt cctatagttg
    71041 cagttggtga tggcagtaat gatataaaaa tgatagagaa tgctgatatt ggaattggat
    71101 ttggaggggt aagacctata gctcctggaa tattaaaagt atgtgattat gcattttatg
    71161 aggaggaacg tttatgccaa ctactaaaac aattgttgta aactgtgcag gtagaggaag
    71221 tagactagga ttaaattcaa ataagtcgtt aatagatata gatggaaagc cattaataat
    71281 aagacaatta gagtgtcttg atgattatga tgacatacgt attgtagtag gctttcaagc
    71341 agaaaaatta attgaagttg tatgttctta tcgtaaagat ataatgtttg tatttaatca
    71401 tgattactta aacactaaga ctgctgcaag cttatcttta ggcaaaaaat attctagaga
    71461 tactgttata tcactagatg gtgatatact ttttttcaaa gaagatttcg ataattttgt
    71521 taacacagat ggagaaatta ttggtgtatg tcaaccgtat actaaagacc ctgtctatgt
    71581 taaaacagac tttattaatg atggagagtt tgctacagaa ttttcaagga caaatggaga
    71641 ttatgagtgg acaggtttgt ttaaaatata ttctaaaaat ttaagctctg gtacaaatca
    71701 tgtatataaa atgatttcac ccaacttacc acttaaaata gctcatgttg aattgaggga
    71761 aattgataca ccggaagaat ataatgaagc tttaaaatgg tataggaaca aaaaataaag
    71821 gagattttat atgggtaatg caacgagaat ttatgaaaaa catgtagata taaaaaaaga
    71881 tactgttcaa gatttttgga ataaacgagc taaaaagcat attccagaga atccctatat
    71941 ttcagtgaaa tgtaatgacc aaaatcctga ttatgctaaa aatttagata aatatgaaaa
    72001 agaaataata attcctaaac taaatataac tagaaattca aatatattgg atataggttg
    72061 tggggtaggt aggttagctg atgatatagt tcctatatgt aactattatc ttgggacaga
    72121 ttttgctgaa gacttaatat ctattgctaa aaaaagattt tctgataatg actgtgattt
    72181 tcaagcatgt gattttatca atactctata tgatacaaaa gttaaatcca aaatgccatt
    72241 tgatacaatt ctattggcag gtgtaacaat gtatataaat gatgatgaat taaaaatagc
    72301 attgaaaaat ttattaggaa tattagataa aaaggcaaca atatatatat ctatacctat
    72361 tggaataaat aagagattaa ctttgaaaga attttactcg aaagaattaa attcagaata
    72421 taatgttata tatagaacta tagaagaata tgaagaaatt ttaaaaccat tactagatga
    72481 aggatttgaa attgttgaaa gcaaaagctt cttaacagat ataaatcaat actctgatac
    72541 agaaaggcat tattttatac taaagcgata gttttaatat aaataaaatc aaaattaagg
    72601 tgaatctgat gaactataat aaaaaaaatg aagttttaaa tcttatacaa atacttatag
    72661 agggtattga ttacataaaa aataataatt taagtgaatc aatagttaat tcatctcttg
    72721 aagctattaa ttatatgaaa aaatatataa ataattctgg aagaagcaat aaaaacttgt
    72781 tgaatttaat tgatgaaact tatgtaaaaa ttttaagact ttccatgtat aaaaatataa
    72841 gacttattga agattgtgaa cttatcataa gtaatttaaa ctatttatca aatataatag
    72901 aaaatagtct aaataaaaaa actaaaattg tatttatgcc ttataatgct aaaatgtgga
    72961 atagtttaga aagtatctgg aaatctgcgg ttttggatga gcagtgcgac tgttatgtag
    73021 ttcctatacc ttattacaag ttaattgata cgcctaatgg tataactcag atatatacat
    73081 atgaaggtaa tgattttcct gaagatgttc cagtaataca ttatgatgat tttgatttat
    73141 ctaaggagaa acctgatata atatatgttc ataatcaata tgatgattgt aacaatgcta
    73201 caatggtaga tagtaattat ttttcttata acttgaaaca atatactaat atgcttgtat
    73261 atgttgctta tggaatactt ggaacttatc ctgttagttt ttacttaaat ttttatgaat
    73321 tgatagcatc tagaaatttt gataaggtta ttgtgcaatc tcctgcattt gaaattatag
    73381 cagaatgtag tggtataaat aaaaatcaaa tactaacaat gggatctcca aaatttgatt
    73441 ctttaattta taatttaaaa cagaagaata taaataaaaa ttatgaatct aaattaaagg
    73501 gtaaaataat tttcttatgg acaactaatc taatgaaaat acctaatggc aaagatggtg
    73561 tcattgatga gattgaaaat gtatttgata ttattgaaaa tagtcaagag tatggtctta
    73621 tatatagacc acatccatta gaacttgagt atgtaaaatc taaagttcca gaatgtttta
    73681 atagatacaa aactttgcta gattcaatat ctataaaaaa taatattatt ttagatgact
    73741 ctgtatctta ctatgaatca ttcaacttat cccatgcttt aataacagat aggtcttctg
    73801 tattaataga atatattcaa acgaagaaac ctatattaat ttatgatata gatatggaac
    73861 gtggatatta tgattcaaga atattcgata tattttcaaa ttatgtagta ggagaagaag
    73921 atatggattt aataaaattt atgaacttag taaaaaataa taatgattat aagctaaatc
    73981 aaagattaaa ttctttaaat agtgtactat caaatacaga tggaagttgt ggtgaaaaaa
    74041 tacatactaa tgtattagaa tacgttttaa ataaccatat ttagttaaaa ttaattaata
    74101 attagataaa tttaggcttg gaaaggagtt aaaacattat caattttaat aaatataaga
    74161 taataaaggg caaattaatt aaagtttgac cttttttaaa tttattttgt tactctatac
    74221 aacattttag actgtattct tatataacca gtctaaaata aaatttatca aaagtagaga
    74281 aaattacaaa ttttttatcc ctaaaagtga aaataaaagg gaaaacttta aacagatata
    74341 aaatcctaag catataattg gaaaataatg ttaaaataaa tgcttttaat gaaattattg
    74401 taaaagacaa atttagaata aatttatttt atattgtaaa tttttgtaa
//
LOCUS       DAEPUT010000007        66475 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.007, whole genome shotgun sequence.
ACCESSION   DAEPUT010000007 DAEPUT010000000
VERSION     DAEPUT010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 66475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66475
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.007"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            193..1269
                     /locus_tag="KRL22_000600"
     CDS             193..1269
                     /locus_tag="KRL22_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1271122.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1372..2214)
                     /locus_tag="KRL22_000601"
     CDS             complement(1372..2214)
                     /locus_tag="KRL22_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH1271123.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEVGSVMGTYTSKGAIL
                     ITAI"
     gene            2398..2970
                     /locus_tag="KRL22_000602"
     CDS             2398..2970
                     /locus_tag="KRL22_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1271124.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3133..3405)
                     /locus_tag="KRL22_000603"
     CDS             complement(3133..3405)
                     /locus_tag="KRL22_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271125.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(3532..4404)
                     /locus_tag="KRL22_000604"
     CDS             complement(3532..4404)
                     /locus_tag="KRL22_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1271126.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4700..7807)
                     /locus_tag="KRL22_000605"
     CDS             complement(4700..7807)
                     /locus_tag="KRL22_000605"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBH1271127.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(7900..8132)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8307..8834)
                     /locus_tag="KRL22_000606"
     CDS             complement(8307..8834)
                     /locus_tag="KRL22_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBH1271128.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8869..9654)
                     /locus_tag="KRL22_000607"
     CDS             complement(8869..9654)
                     /locus_tag="KRL22_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBH1271129.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9664..9921)
                     /locus_tag="KRL22_000608"
     CDS             complement(9664..9921)
                     /locus_tag="KRL22_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBH1271130.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9940..10398)
                     /locus_tag="KRL22_000609"
     CDS             complement(9940..10398)
                     /locus_tag="KRL22_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBH1271131.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10438..11142)
                     /locus_tag="KRL22_000610"
     CDS             complement(10438..11142)
                     /locus_tag="KRL22_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBH1271132.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11152..11787)
                     /locus_tag="KRL22_000611"
     CDS             complement(11152..11787)
                     /locus_tag="KRL22_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271133.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12168..13208
                     /locus_tag="KRL22_000612"
     CDS             12168..13208
                     /locus_tag="KRL22_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1271134.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(13671..15026)
                     /locus_tag="KRL22_000613"
     CDS             complement(13671..15026)
                     /locus_tag="KRL22_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HBH1271135.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(15052..15321)
                     /locus_tag="KRL22_000614"
     CDS             complement(15052..15321)
                     /locus_tag="KRL22_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH1271136.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(15611..17566)
                     /locus_tag="KRL22_000615"
     CDS             complement(15611..17566)
                     /locus_tag="KRL22_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271137.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYNIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGEDFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKSVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCIL
                     TPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(17749..19224)
                     /gene="spoIVA"
                     /locus_tag="KRL22_000616"
     CDS             complement(17749..19224)
                     /gene="spoIVA"
                     /locus_tag="KRL22_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HBH1271138.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(19396..20691)
                     /locus_tag="KRL22_000617"
     CDS             complement(19396..20691)
                     /locus_tag="KRL22_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1271139.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSVINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPIASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMVYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENATKVS"
     gene            complement(20802..21953)
                     /locus_tag="KRL22_000618"
                     /pseudo
     CDS             complement(20802..21953)
                     /locus_tag="KRL22_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986090.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(22005..23144)
                     /locus_tag="KRL22_000619"
     CDS             complement(22005..23144)
                     /locus_tag="KRL22_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1271140.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDTKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            23463..24113
                     /locus_tag="KRL22_000620"
     CDS             23463..24113
                     /locus_tag="KRL22_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1271141.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRNVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(24270..25289)
                     /locus_tag="KRL22_000621"
     CDS             complement(24270..25289)
                     /locus_tag="KRL22_000621"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH1271142.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(25320..25934)
                     /gene="plsY"
                     /locus_tag="KRL22_000622"
     CDS             complement(25320..25934)
                     /gene="plsY"
                     /locus_tag="KRL22_000622"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBH1271143.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(25969..27288)
                     /gene="der"
                     /locus_tag="KRL22_000623"
     CDS             complement(25969..27288)
                     /gene="der"
                     /locus_tag="KRL22_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBH1271144.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTYFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(27322..28650)
                     /locus_tag="KRL22_000624"
     CDS             complement(27322..28650)
                     /locus_tag="KRL22_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HBH1271145.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(28888..29088)
                     /locus_tag="KRL22_000625"
     CDS             complement(28888..29088)
                     /locus_tag="KRL22_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271146.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(29090..30022)
                     /locus_tag="KRL22_000626"
     CDS             complement(29090..30022)
                     /locus_tag="KRL22_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH1271147.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(30067..30999)
                     /locus_tag="KRL22_000627"
     CDS             complement(30067..30999)
                     /locus_tag="KRL22_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH1271148.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(31054..32343)
                     /locus_tag="KRL22_000628"
     CDS             complement(31054..32343)
                     /locus_tag="KRL22_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1271149.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDMVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(32372..33064)
                     /locus_tag="KRL22_000629"
     CDS             complement(32372..33064)
                     /locus_tag="KRL22_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271150.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(33079..33840)
                     /gene="pgeF"
                     /locus_tag="KRL22_000630"
     CDS             complement(33079..33840)
                     /gene="pgeF"
                     /locus_tag="KRL22_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HBH1271151.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(33837..34298)
                     /gene="nrdR"
                     /locus_tag="KRL22_000631"
     CDS             complement(33837..34298)
                     /gene="nrdR"
                     /locus_tag="KRL22_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBH1271152.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(34320..34583)
                     /locus_tag="KRL22_000632"
     CDS             complement(34320..34583)
                     /locus_tag="KRL22_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH1271153.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(34687..35460)
                     /gene="sigG"
                     /locus_tag="KRL22_000633"
     CDS             complement(34687..35460)
                     /gene="sigG"
                     /locus_tag="KRL22_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HBH1271154.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(35552..36274)
                     /gene="sigE"
                     /locus_tag="KRL22_000634"
     CDS             complement(35552..36274)
                     /gene="sigE"
                     /locus_tag="KRL22_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HBH1271155.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(36299..37171)
                     /locus_tag="KRL22_000635"
     CDS             complement(36299..37171)
                     /locus_tag="KRL22_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HBH1271156.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(37461..38735)
                     /locus_tag="KRL22_000636"
     CDS             complement(37461..38735)
                     /locus_tag="KRL22_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH1271157.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(39019..40176)
                     /gene="ftsZ"
                     /locus_tag="KRL22_000637"
     CDS             complement(39019..40176)
                     /gene="ftsZ"
                     /locus_tag="KRL22_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBH1271158.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(40366..40719)
                     /locus_tag="KRL22_000638"
     CDS             complement(40366..40719)
                     /locus_tag="KRL22_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HBH1271159.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(40818..41492)
                     /locus_tag="KRL22_000639"
     CDS             complement(40818..41492)
                     /locus_tag="KRL22_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH1271160.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VDLFAK"
     gene            complement(41497..42195)
                     /locus_tag="KRL22_000640"
     CDS             complement(41497..42195)
                     /locus_tag="KRL22_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH1271161.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(42218..42958)
                     /locus_tag="KRL22_000641"
     CDS             complement(42218..42958)
                     /locus_tag="KRL22_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HBH1271162.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(43228..44454)
                     /gene="murG"
                     /locus_tag="KRL22_000642"
     CDS             complement(43228..44454)
                     /gene="murG"
                     /locus_tag="KRL22_000642"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH1271163.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSASKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(44472..45602)
                     /gene="spoVE"
                     /locus_tag="KRL22_000643"
     CDS             complement(44472..45602)
                     /gene="spoVE"
                     /locus_tag="KRL22_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HBH1271164.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(45654..47009)
                     /locus_tag="KRL22_000644"
     CDS             complement(45654..47009)
                     /locus_tag="KRL22_000644"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBH1271165.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(47028..47996)
                     /locus_tag="KRL22_000645"
     CDS             complement(47028..47996)
                     /locus_tag="KRL22_000645"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBH1271166.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(48037..49410)
                     /locus_tag="KRL22_000646"
     CDS             complement(48037..49410)
                     /locus_tag="KRL22_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBH1271167.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(49577..51556)
                     /locus_tag="KRL22_000647"
     CDS             complement(49577..51556)
                     /locus_tag="KRL22_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HBH1271168.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIEAFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(51568..51915)
                     /locus_tag="KRL22_000648"
     CDS             complement(51568..51915)
                     /locus_tag="KRL22_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271169.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(52396..53331)
                     /gene="rsmH"
                     /locus_tag="KRL22_000649"
     CDS             complement(52396..53331)
                     /gene="rsmH"
                     /locus_tag="KRL22_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBH1271170.1"
                     /translation="MEFHHVSILLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(53361..54107)
                     /locus_tag="KRL22_000650"
     CDS             complement(53361..54107)
                     /locus_tag="KRL22_000650"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBH1271171.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(54501..55787)
                     /locus_tag="KRL22_000651"
     CDS             complement(54501..55787)
                     /locus_tag="KRL22_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH1271172.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPEGVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDIIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(55802..57067)
                     /locus_tag="KRL22_000652"
     CDS             complement(55802..57067)
                     /locus_tag="KRL22_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH1271173.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            57383..58480
                     /gene="ychF"
                     /locus_tag="KRL22_000653"
     CDS             57383..58480
                     /gene="ychF"
                     /locus_tag="KRL22_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBH1271174.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
     gene            complement(58959..61238)
                     /locus_tag="KRL22_000654"
     CDS             complement(58959..61238)
                     /locus_tag="KRL22_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1271175.1"
                     /translation="MLSDAKNNRYGLFIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(61509..62963)
                     /locus_tag="KRL22_000655"
     CDS             complement(61509..62963)
                     /locus_tag="KRL22_000655"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBH1271176.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVLDGHKYIKDAIEKGASAFLVEEDVAIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            63127..63996
                     /locus_tag="KRL22_000656"
     CDS             63127..63996
                     /locus_tag="KRL22_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1271177.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDATSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(64209..66281)
                     /locus_tag="KRL22_000657"
     CDS             complement(64209..66281)
                     /locus_tag="KRL22_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1271178.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PVLANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPTIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENTLVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVTTAKEENRVSIL
                     RDDIEKIG"
BASE COUNT        21067 a        11918 c         7120 g        26370 t
ORIGIN      
        1 atttattact tttataaaat tttcacaata aaaagtcatt ttacttccgt atttaatgca
       61 aaagtagaga ttaaacttaa tataaaaaat atataacaaa tttttttata tttctagaag
      121 aaaagtatac tcttttttgt ttaataatgc taaaattgat ttgtattgaa ttttgattag
      181 gaggaaatta ttatgaaagc tcaaagatta aatgctgtac ttgaacaaat gaaaaaagat
      241 gatatttctc aaatgttagt aagtgaccct acttctatat tttatcttac aggagtacta
      301 atccatccag gcgaaagact attagcatta tacttaaatt taaatggtaa taataaatta
      361 tttataaatg aattattccc agtttcagaa gatttaggtg ttgaaatggt ttggtttaat
      421 gatactcaaa atccagtaga aataataact gaacatatag acaaaaatgc tactatgggt
      481 gttgataaaa actggccagc tagattctta ttaaacttaa tagaattagg tggaggaagt
      541 aagtttgtaa attcatctta tataatagat actttaagaa tgtgtaaaga tgaagaagaa
      601 aaagagttaa tgagaatagc ttcaaaatta aatgacaagg ctatggaaca acttaaagct
      661 actgtttctg gtgaacttac agaaaaacaa cttgttggta aattatctaa aatatatgaa
      721 gacctaggta ctgatggatt ttcatttgac cctattatag gttttggacc taatggagct
      781 aatccacatg gtgaacctgg aaatgcactt gtgaaaccag gagatgcaat aatattagat
      841 ataggttgta taaaagataa ctattgtgct gatatgacaa gaactgtatt ctataaagaa
      901 atacctgaaa aaggtagaga aatattcgaa atagttcttg aagctaataa gagagctgaa
      961 gctattgtaa aaccaggtgt tagattctgt gatatagatg ctgctgctcg tgactacata
     1021 actgaaaagg gatatggaca gtacttcact catagaactg gtcactctat aggacttgaa
     1081 gttcatgata aaggagatgt atcttctata aatacagata ctgtacaacc aggaatgata
     1141 ttctctatag agccaggtat atatttacca ggtgagttcg gagttagaat agaagattta
     1201 gtacttgtta ctgaagatgg ttgtgagata ttaaacaaac atgacaaaga aatatgtgta
     1261 gttggttaat tctaaaatca atttgataaa attaaaaagc catataaaaa tgttttaaac
     1321 atttttatat ggctttaatt tctcaatcta tgatttattt caatccatta tttatattgc
     1381 agttattaag attgcaccct ttgaagtata tgtacccatc actgaaccaa cttcacagat
     1441 tacaacatct ttgtatttta catccttttc cataacttcc cttacctttt gagccttttc
     1501 tgggcaatta gcatgtccta taaataaaac cttttcttct ttatctttaa tttttgactc
     1561 tactaaagta atcagctttt tcaaactgtt tccttcgcct cttgccttat ctataggagt
     1621 tacaacgcca tctgcaactt gtattatcgc cttaaaattc aaggtattta taatttttcc
     1681 tgctattgga tttattctac cacctttaat agcattttct aaagtttcaa gtgttccaaa
     1741 aaatggagga ttatctttat atttatttat tattgaaaca atctcttcaa tttcttttcc
     1801 ttcttttatt aatattgctg cttttaacac taattgtcct attccaattg acccactaag
     1861 tgaatctata acctcaactt tcttgttatt tccttccttt tcaaacatat cttttgctaa
     1921 aagtgcacta ttataagtcc cagataatcc tgaacttata ttaatcacta atacactttc
     1981 ttcctgacaa tggtatgctt ctaaaaattt atcaggagaa ggacatgatg tttttggtag
     2041 tactttactc tcactcattt ttctatagaa agtttcatta tctatttcct ttccagatat
     2101 ataactttct tctccaaaag atacatttaa accaacaact tctatgttgt atttttctat
     2161 tatatcatca ggtaagtcac atgcactgtc cactatcaat tttattttat ccatattaac
     2221 ctcactataa gatattattt tatttattca gtcggtcgta cgaccgattt aattattatt
     2281 ttatatattg aatgaaaaaa agtcaataga tatagattct cgctttattg acaataaata
     2341 tccataagct tataatgtta ttaatttgtt ataaatatac atggaaaggt aggttttatg
     2401 aaaacaaata atatgaaaca ggctatttta tcatctgcaa ccaatttaat agccaaaaat
     2461 ggagttcaaa atactagcct tgctgatatt gcaaaagatg taaatataag taaaggtact
     2521 ttgtattatc actacgcatc taaagatgat attatatatg atattgcgga tactcattta
     2581 gaagttataa ctagtgctat actaaactgt gtaaaaaatg ttaaatcaaa aaattctcaa
     2641 atagaaatgg ttaacttaat cttagagaaa atatctacta tagaaagtcg tggtagggta
     2701 catatgtatc ttatttgtga ggcaattact tcaaataatg atttaaagga aagaataaga
     2761 ttaaaatata ttgaatggag aactactctt aaatctgaaa ttgttgaatc actagaaaaa
     2821 tataatagta gcgaaaatga acaggatgct gaatcatttt cttttttact catgtcaata
     2881 gttgatggtt tagttgtcca aagtttatta aaaacagaaa aaatacctta tgaaaatata
     2941 gcttcttttt tagttaatca ttggatttaa acttaatact tagataatta ataaaagtga
     3001 actatttaag ttatctactt taacagttca ctttcttatt tattctcaat aatttttact
     3061 taaaacattc aatttttatt taaaccttca tggaatcaca aaataaaaat ctcttataaa
     3121 tttaaaatgt ttttatttat gttcatgtgt atgcccatct gaatgttcat gaccatgtgt
     3181 atgtgtatgc tcatggctat gctcatgagt acctgaaaaa ccatcatcat gattatggtc
     3241 gtgacctaca ccatttacat gctcatgttc atgcccatga ctgtgagaat gttgatgtga
     3301 atgttcatgg ttatctcctc cacagcatcc ttctcctcca gtcccacaac acccacttgt
     3361 atgtggatta tgatgatttc ttactacaaa tctctctctt aacataattc ttatacctcc
     3421 tagtatatta ttgagtactt catgtacccc attaactaca gtatacatct aactaggtat
     3481 aatctcaata catatggcat tttttaacat atataattaa catatataat cttaaagaaa
     3541 tttatcctta aaacctccac cttttacttc ttcaacgtta ttgacagaaa taaaagcttc
     3601 actatccata tcataaatta aatctttaaa tttacctatt tcatttgcag atattataca
     3661 ataaatcatc tttttcttat tttgtgtata tgcaccttct gcctccaaaa aagtgactcc
     3721 tctacccatt ttattcatta tcactttgga tatttcatca tatttatttg atattaaaag
     3781 tatagatttt tttctatcaa agcaatcttt tcctatatcc atagtaaaag aaattatata
     3841 cattgtaatt aaagtgtaca tcaccaattt agctccaaat aaaaaagctc ctgcacatac
     3901 tacaaaaaaa ttaataaata aaaatgtatt tttcataggt atatcatact ttcttttcat
     3961 tatggctgct attatatcaa gtcctccagc agtagctctt gctttaaaag ttaaccccat
     4021 acctatacca gttaatgcac caccataaat acactgtagc atagtatcat ctattgggaa
     4081 atatttagca atatcttgtg ttagccccag tgctagagaa aatagtaaca tattgacaaa
     4141 acttattagc aaaaatttat tatcaaaata ctttctagct ataataaata ttggtatgtt
     4201 catcaagaaa cttgatattc cctgatttat accaaataat ttgtataata taacacaaat
     4261 tccagctact cctccactta ataacttggc tggtgctaga tataaattta ttcctaaggt
     4321 tgatagaatc atacccaata taataagaca atattgtaaa aatatattat tatcaatact
     4381 tagcttttta ctttcaccat acatcaaaac gcaccccttt gcataataaa taaaccaccc
     4441 tgcataacac acgataaatt tacaaataaa tttatcagaa gtagtttcct aaaaatatta
     4501 ttcatcctca cttaaacgtt tattcattaa tattctatca catgacataa ataatttata
     4561 tgatttatat agatttattt attgtaaatt ttggaatatt aaaacatttt attgaataga
     4621 taattatatt acataaaaaa tccctataga aatctataaa ctaatttcta tagggatttt
     4681 ggttaactaa ctattctttt tattttttta taacttttat acctgtcata tggtcattta
     4741 agttttgttc ctctaaagat ttatcatcta ctctgtttat ttctaaagct aaagtttcag
     4801 acttgatata ttcattaaaa tggtcaacag ccttagcaat ttcatcatca ccacagtatt
     4861 ctattactat attatctaat acttcaaagt tattagattt tcttaattgc tgtactttag
     4921 atataaattc tctagcataa ccttcattaa tcaattcttc agttagctta gtatctagta
     4981 taacaaaaag attgttttca acagatacat taaatccttc cttagcagtt atacctatta
     5041 atactaaatc cttattaaat tcaaaagctt caccatctaa atcaactgtt aaagtctcac
     5101 ctttttcaag tttattagca gtttcatgag catttaattt acttaatgct ccaacgaata
     5161 aattcatctt agaacctaat aatggccctg cttccttaaa gtttggtttt aaactaaagt
     5221 tcatatactc atctaaatcc ttagcaaata ttacctcttt aacattaagc tcttctttta
     5281 ttaaatcaac tacatcactt attgtatctt caaacttacc atctactaac actttttgta
     5341 atggttgacg aacttttatt ctttctactt ctcttgaagc tctacctaaa gtaactaagt
     5401 ttttagctaa atccattttt tcttctaatt tagtatctac taactcttca ttacatttag
     5461 gatattcagc taaatgaaca gatacttctc ctgttaagtt tctatacatt tcttctgaca
     5521 tatatggtgc aaatggagct atagctctac aaagaccatg taacaattca taagttgtat
     5581 tgtacactgc ttttttatct tctgttaatt cagttgccca gaatcttctt cttgaacgtc
     5641 ttatatacca gttagataaa tcatcattta taaaatcttg tatcattctt aaagttttat
     5701 ttaactcaaa tatagctaaa ttttcttcta catctttcat taaattattg aacttagata
     5761 atatccatct atcaagttct ggtctatctt tatattctac aaaaaattca gttggattta
     5821 tatcatctgt gtttgcatat aaagtaaaga agttatatac attcttcata gtacctataa
     5881 atttactttg gatttctttt aatccatcca tatcaaattt agttggagtc catggtggag
     5941 aaacatatag taaataccat cttaatgcat ctgctccata ttggtcaaat aattccattg
     6001 gatttactgt atttcctctt gatttactca ttttcttacc atctttatca agtacaaggt
     6061 ctggaactaa aacactctta tatggtgctt ttcctaatac aaatgttgat actgcaagta
     6121 atgagtagaa ccaacctcta gtctggtcta taccttctga tatatagtca gctggaaaca
     6181 attggtcaaa gttttcctta ttttcaaatg gatagtggtg ttgagcaaat ggcatagccc
     6241 cactatcaaa ccaacagtct ataacctctg ttactcttgt cattggtttt ccacattttt
     6301 cacattttaa gtgtatatca tctacatatg gtctatgaag ttcaactgtt tctggattta
     6361 catcttctat agctttttca gctaattcag ctcttgaacc aactgaatct gtatgaccac
     6421 attcacatct ccatatagga agtggagttc cccaatatct agttcttgat attgcccagt
     6481 catttagatt ttctaaccag tttccaaatc tcttctctcc tacaaaactt gggaaccatt
     6541 ttacaccatt attattttct attaatttat ctttaagttt agtcatctct atataccagc
     6601 ttggttttgc atagtatact aatggagttt gacatctcca gcagtgtgga taattatgaa
     6661 ctactttttc tttgctatat aatttatttt cagaagctag ccattttatt atttcaacat
     6721 ctagcccatc ttccattaca aatctacctt cccaaggagt agatgtaaat ttaccagttt
     6781 catctactgg ttgaataact ggtaaatcat atcttttacc tgtgttgtag tcatcttcac
     6841 caaatgctgg tgctgtatga actataccag ttccatcttc agtagttaca taatctccta
     6901 ctgtaataaa aaatgctttt ttgtcaactt ctacaaaagg cattaattgt tcatattcta
     6961 aaccttctag gtctttacct ttcatttctt ctaaaacttc ataatcttca cctagtactt
     7021 tatcagctaa aggtttagat acataatata cctcatcacc ttttttaact tttaaatagt
     7081 ctacatcagc atttactgtt aatgaaacat ttgatggtaa agtccatgga gttgttgtcc
     7141 atgctaagaa gtattcatca gcatcttttt tcttaaattt agctataact gtattagttt
     7201 ttacttcttt atatccttgt gcaacctcat gactagcaag accagttcca catcttgggc
     7261 aataaggaag tattttatgc ccttcatata tatatccttc tttgttgaat ttgtttagta
     7321 tccaccatac agactctata tagttattat ctaaagttat atatggatta tctaaatcaa
     7381 cttcataagc cattctctca gtcattattc tccattgttt ttcaaatgag aaaactgact
     7441 ctctacattt ttggttaaat tcagctattc catattcttc tatttgttgc ttactagtaa
     7501 gtcctaactc tttctctact tgtatttcaa ctggtaatcc atgtgtatcc caaccagctt
     7561 ttctctttac ttgataacca gacattgttt tatatctaca aactgaatct ttaagcgttc
     7621 tagataaaac atggtgtact ccaggatttc cattagctgt tggaggtcct tcatagaata
     7681 cgaaacttgg gtcatctttc cctttttcta aagttttttc aagtatattt atgtctttcc
     7741 aataatcaaa aacttgtgct tctgcttgtt ttacagaact gtctaccaat ggcttaaatt
     7801 tcgccatgta aatcaccctt tcctactaaa tattataatt ccaaaatttt ttattctttc
     7861 acataaattt aaatactaaa aaactcgccc cctttaaacc aaagggacga gttataaatc
     7921 gcgttaccac cctaattcta tatgtaaact aaatactagc tacatataac actctaatag
     7981 tataacggta ctaaccggca cagcttagta gaatttaatc gttcagcctg cagctcaaga
     8041 gtgattttta tctttataaa ttcattggtt ctcagcatac ccaattctct gtaaaattat
     8101 ctaaagataa atgtctctat caacgctttt aaaaatttat ctgtgtttat atgaaattct
     8161 ataacaaata atttgaatag tcaatatatt tttgaaaaat ataataattt ctatttttct
     8221 tacattttta tcctattttt aatctttgtt atagttttct caaactcaca caattattct
     8281 acataaaaaa taaacaaatt acaagcttat tctaaagttg tagcagcttc atcattacta
     8341 taattataca ctgttgttcc ttcaaatgca tttacacatt tttcatctac atcataaaaa
     8401 atctcatcaa cacttcttat ttcatcttct aacagtgatt taaatttatt tctaaatatc
     8461 ttaaattctt taactaaagc atcatactct tttcttatct ctataacacg gttattagct
     8521 tgttctataa tttgtctagc ttttaaatca gcttcttcaa caattatctt agccttttta
     8581 ttagccgcgc tacaagtgtc ttctgctgca ctttgagcag ttattaaagt agcttttagt
     8641 gtttcttcaa tattttcata cttgtttact tggtcttgat ataaccctaa tttttcttta
     8701 agagctgtat tttccctaca tagagattca taatcttcct tgatgatatc taaaaattca
     8761 tcaacctctt catctctata ccctcttaaa ccttttttaa actctttatt ttctatctca
     8821 attggagtta gcattacatt tcctcccagc tataatttaa attagtcctt atacaattaa
     8881 tcttgcttga acttttattt ttcctttttt agtaatatct cctatttgtg ttaccttagc
     8941 tcttcctttg cctctaatag aaatcaaatc atcgtttttt actattttag aagttgaagt
     9001 tatcttttca taattgacat ggactttttc tccatttatg tattttgcac tatcttgtct
     9061 agatatattg taaataccac ttatcacaca atctaaccta tctgaagata ctgtaaatga
     9121 tacttcttta tattttgaag aactattaac aatattttct ctggaaattt cctttacaat
     9181 tacattattt cttgaaacct tttctaagtt tacaattata aaatcgcaaa tatcactact
     9241 tacaactact tgacaaaagc tatcatgtat aattatatct ccaatttttt ctctttttat
     9301 acctagaccc agtattgacc ctaagtaatc tttatgagat atatttttaa atttgaaatt
     9361 cccttctatt tgtaaaaatc taagagtatc ttctatatct tcatattcca tgtaaaatgg
     9421 ataaataaat acagtgcttc tttcagcttg ttcataacct ccatccacac tgtattttat
     9481 ttcatttgta gaatttaata ttgctacagc atttttcact tcatatggat taagaaactc
     9541 cgtagactta acatcatagt tttttataca actattagcc ttgtctatca ctttaaacat
     9601 tttatttttc aagtctatat cctttatgtg atttgttagt tttaatttat ccatcctatc
     9661 accttagaat ataaccaata ctaattgtct taggaacatc aataatacta ttgcaattaa
     9721 aggagaaaaa tctataggtc catttgtata tttatacatt atagacctta ttggcccttc
     9781 tattggctct gtaagatttt ccaaaatatc aaaaatttta ctttgtcttc catttggaaa
     9841 ccaagtcatc aagcttttta taactatcat ccatgctatt atatctaaaa gataataaag
     9901 tgcaattctt attgttccca tatattaacc gcctttttac tatttatttt gccaagggaa
     9961 gaatgcttta ctttctaatt cttttttcat atttgcatct atatccacat tattaggagc
    10021 tagtataaat attgatttag aaaccttttg tatacttcca tctaagacat aaactgcccc
    10081 attcataaag ttaaatatag atttgcgaac ttcagaatta gtcaatcctt ccaaattcac
    10141 tataactgcc cttctttgtt ttagatggtc tgctatagtt gcagcttcat cataaacctt
    10201 aggttcaact attacaactt tcatttggct agttgtatgt aaatttacaa ttttatttgc
    10261 ttttgcagta ctaaagccac tgttcatttc ttcttcttga actatatcgt ccatgccact
    10321 ttcatattca tcttcaatgt aatcttcttc ttcatcaact atccaattct taaatttaga
    10381 tattattcca tttgacatta ttaacttcct ccttaaaatt tattcaaatt tgagtaatta
    10441 ttttttattg tagtttcttt ctccaaagat tgatgttcca actctaacaa tggtagcccc
    10501 ttcctctata gcaatttcat aatcgtgact cattcccatt gacaaaacat ccatccctac
    10561 attagggatg tttagttctt ttatttgttt tgataaatct ttaagacctt taaatacacc
    10621 tcttatctca tcttcatctt ctataaaagg tgccattgtc attagaccct ttatttttat
    10681 atttttatat ttttctgaca cttctttgac aaagtctaca acttcttctc tatcaagtcc
    10741 atgcttagac tcttctttag atatattcac ttgtactaag caatctattt ctctgtttat
    10801 ttgttctgca cgtttttgaa tttcttcgca taatgcaatt ctatctaaag agtgtatcat
    10861 acaaacttta tcgattatgt acttaacttt attggtttgc aaagttccta tcaggtgcca
    10921 gtttaattta tcacctataa tatcatactt tctagctaat tcttggggtt tattttcacc
    10981 aacagaagtg attccttccc tcattgcctc attaactaag tctacatcaa cagtctttgt
    11041 gactgccaaa agggtaatct ctttgctgtc tctatctact ttttttgcag ctttatcaat
    11101 tttgtttctt atctcagaca aattatcttt aatagaaccc attattatca cctactttat
    11161 ccttatattt gtgtttatac tgttaggtct taaaattatt ttgtcatata gattaacact
    11221 tgtaactcca tttatgtcat ttttataata atccacaaat acagaagatt cattctcata
    11281 agttattcct tctaatatga caaattttac actttgtgat tgttcatcaa ttacatatac
    11341 accacgttta ttgtcttttg tttttataga agttttaggt atttttaaac attccatctg
    11401 attatatatt atatcaaatt cttcgacact tgtatcctga tttgcaacaa tttggttact
    11461 tatttttaat tttaccatta ttttattatt attttcatat attttgtaaa cttttgcatc
    11521 taatttttgc tcatgatatt caattattac attttgattt ttttcaaagt tattagaatc
    11581 ttctttactg atgtatgtag atagataatt actctggtca ttggcatctt tttctatagt
    11641 tccttttaca tgaatctttg catcaacttt ttcatttttt aacaccaacg tatctacatt
    11701 tttgctaatt atcattacta atatattaaa tactaaatat ataagaatac caagtatcac
    11761 taatctggta tattttacct ttttcaaaga ctctccccct ataaaattac tttcattata
    11821 agtacttctt ctaaaaaatg tttattcctt ttttataagc taatatttta cgttctaata
    11881 attatttttt ccatattaaa tttatttttt atcaatcttc ctatacaaga ctgcattatt
    11941 tatatataat tgtattataa agtataagtt taatttacat tttatacgtt aagcttactt
    12001 tatatgtttt tatagttatt tttattttta gatgcaatat aaaaccaatt aagatttaaa
    12061 ataacttttg ttatgttgac atttatttag gtaatcattt atgaatcagg ataacgttat
    12121 cataacaaaa gtttatgtcc taaaaaaaat acaaggagga ttttcttatg tcagaaattt
    12181 tattaggaac aggtttactt ttattggttc tatgttgttt cacaattttt agttacaagg
    12241 ccccatatgg tatgaaggct atgggagctc tagcaaacgc tgcatgtgct actttcttag
    12301 tagaggcatt caacctttct ttacttggtg atgttttagg tatggaattt tttagaagtg
    12361 ttggagctgc taatggtagt cttggtggag ttgctgctgc tatacttgtg cctttagcct
    12421 taggtgtatc tccagtttat gcagttttaa taggattatc ttgtttagat ttttctatat
    12481 tatctggatt cgttgctgga tactttgttt ctttcttaat taagtttata gagaaaaaag
    12541 tgccacctgg agtggattta gtggttgtaa ttcttctatg tgcaccacta tctcgtctta
    12601 tagcatcaaa tgtagaccca ttagttaata gtacactact acaaattgga caagttttga
    12661 tagaagctac caacattagc cctataataa tgggaattat actaggaggt ctaataacag
    12721 tagttggaac gtctccactt agttcaatgg ctcttacatc tataattggt cttactggtc
    12781 ttcctatggc aataggagca ttaggtgctt ttggttcagc ttttatgaac tcaacactat
    12841 ttgcaaaatt gaaattaggt tctaaaaaag atattatatc tgttgctatt gaaccattaa
    12901 cccaatcaga cataatttca gctaatccaa tacctatata ttctactaat ttctttggag
    12961 gagccttttc tggtatcatt gtagccttga tgggtcttgt aaacatgaca ccaggtacag
    13021 ctacacctgt ggctggtttt gctataatgt ttgcttataa tccagttcaa caagttctta
    13081 taacagctgg tttatgtgct ttattcaatg taattgcagg atttttaggt tcaaaaatat
    13141 tcagtacctt taaagttctt actgctggtg aaatacgtgg tactgatgta gaagaagaaa
    13201 ttgcttaaaa aacaataaga tttataaatt tatatctcaa gtagtagagt tttatattgt
    13261 aggcaatttt attaattgca aacgttttat tttttattta tgtttatgat tattatgtgt
    13321 gttgaatatt tagataaatt tttatttatt atttttattt agatttttgt ttagtttttt
    13381 atttggttga tatattagga ataaaaatta gtatagttta ttactagtta gatagcataa
    13441 ctttttagat acataaaaaa ttttatatta attagatatt attaaaataa aagcgataca
    13501 tgaattttta aatgtccatg tatcgcttta tttttgccat aatcttaaca actaattttt
    13561 aaagtttatt atcttaacaa agttcattat cttatataat atttaaatgc atagacttct
    13621 ttaatttaac catctaaata tttaattaaa tattattata tgtaatataa ctaattttta
    13681 aatgaatgta taggagctgg aatccttcct cctctttgag taaataattc agatgaattt
    13741 gtatttatag gcattactgg tgctcgtcct aaaagtcctc caaattctac catatcacct
    13801 acatcacatc ctggggctgg tataattcta acggctgtag tcttattatt aatcatacct
    13861 attgctgcct catcagctat catggctcca agcgtacctg ctgtagtatt tcctggcaca
    13921 gctatcatat caagacctac agaacaaata gcagtcattg cttcaagctt atctatactt
    13981 aaagcacctt taataacagc atcaatcata cctgcatctt cagatactgg tataaacgct
    14041 ccactaagtc ctccaacatg tgaacatgcc attactccac cttttttaac agcatcattt
    14101 aaaagtgcta atgctgctgt agtcccatga gtaccaacaa cttcaagacc catttcctct
    14161 aatatatttg ctactgaatc accaatagca ggtgtaggag ctagtgataa gtctattatc
    14221 ccaaatggaa catccaatct actagaagct tcctttgcca caagttgtcc aactcttgta
    14281 attttaaatg cagtcttttt aactgtttct gaaacaacat caaaaggctc tccctttact
    14341 ttctctaaag ctctcttaac aacaccaggg ccacttacac caacatttat aattctatca
    14401 gcctcaccaa caccatggaa agctcctgcc ataaatggat tatcttctac tgcattacaa
    14461 aatactacta attttgcaca accaaaacct tttgcatctt ttgttaattc tgcagtttct
    14521 tttatgattt ctcccatttc tttcactgca tccatattta taccacatct tgtagaacct
    14581 acatttactg aagcacatac tttattagta cttgctagag cttttggaat tgacttaatt
    14641 agtatcttat caccttttgt atatcccttt tgaactaatg ctgagaatcc accaataaaa
    14701 tctataccta aatcctctgc agccttatcc aatgtctgtg caaactttac atagtcattt
    14761 tcatctgttg cacctgcaat aatggaaatt ggagttactg ataccctttt atttacaatt
    14821 gggataccaa attcacgctc tatatctttt ccaaccttca ccaaatcttt agcagaactc
    14881 ataatcttat tgtatatttt ttctctagct ttatctccat cagggtctat acaatctaat
    14941 aaagaaatcc ccatagttat agttcttata tccaactgtt cttcatctat catctttatt
    15001 gtttcaagta tatttcctac attcactatt atcacctccc cttactgtct actacagatt
    15061 atgcattgaa ttaaatattt cttctcgctg aatttttaca tccactgata atttcttacc
    15121 tctttcaacc aagtcctcaa ccgttttctc aaaagaattt aatgatttct ccaaatcaac
    15181 tatcataatc atagtaaaat aatcctgtaa tattttttgt gatatatcta ctatgttgat
    15241 attttgcttg tataattcat cactaattcc tgccactata cctggtttat cctttccaat
    15301 tactgttaaa attgctttca taataatatc ctcccttatt tttttataaa tcttatattt
    15361 ttacaaattg aactatgtgt taacatatat ttcatttatt tgttagtaaa ccacttttta
    15421 tgtatatatt taatatattt taatacctat acattcattt gtcaattttt tttcaatatt
    15481 ctattatttt tatactattt agaaaattca tatattatat atgttttctc aacaataaat
    15541 acagttttca taataatgaa aggtattact tagcaatctc atgattttct aaataatacc
    15601 tttctaaaaa ttattttttt aattttatga atttaattat actttttcta gtatcaggat
    15661 ttacaattaa tatagaacca atcataattg gtgttagtat acaaaataaa aaaataatat
    15721 ctttttttag attatattct ttagattcta atttataatt attatttatt attccatcat
    15781 aatcacttat atttgactta tttttatttg tatcttgatt tttgttagaa atactttccc
    15841 tataaggaaa agaatgttca ttggtaccaa atactgattt tgagcttaaa tcataattat
    15901 catcattttc tgtaattgaa tttttattgt aaaatccttt ttctttatca gaattatttt
    15961 ctttattacc gtctttaggt atatcatgag gatttttatt ttcattgcta tcagtacttg
    16021 attctacatc atctttagga gtatttggtt gtttctcatc agaattatca ttttcattat
    16081 tattattttc attattattg ttttgattgt tattactatc attattttca tttccattat
    16141 tcccatcttg attgttatca tcctcatctc tatccgggtc gtctctacct cctcctccac
    16201 ggtcaccatc aatatcatca ttttcccgtt catcatctgg tgtctcttgg ttgtctccgc
    16261 ctcccattat aaatcctggt ttaaaaacta tatttgaata cccttctttt aatcctccta
    16321 ccacttttac tctaaaacaa cgcaacttaa aatcttcaaa aaaaagtatc gcttgatctc
    16381 taatatcctc ctgttcttca gatatccaat tgattccatc gcttgaatat tcaacaaaaa
    16441 ccttacttgc actatacggc atatcataaa ataaaacagc tacatatcca ttttttgtat
    16501 tttgaaattc cagttccaaa ttgtctattg gttttttctc tataacagat acattcaaaa
    16561 taggaactac atcatcattt attataattt tttctttatt taacatttct gttttaaact
    16621 ttcctgttat attaaaatct tctccctttt ccaacttttc ataataatca gtaaaatccc
    16681 attctacatc tatatcaagt cgattaccac tagatgtttc taataccata tatttgggaa
    16741 attttatatt ttctatttta tcatctttac ttacttttat ttcatcacta aatacaccaa
    16801 ttcccctatg acaacatttc acaatattat agccagaatc ttcagctata gagggtataa
    16861 gctcattata atcatcaatt atataaactt tcttactttc tgatataatt gattgtgcca
    16921 acttattatt atctcttagt aacccacttt cattgttgct actatatgct tttattgaag
    16981 tttcttctat ctcaacatca cctttagaat aaacacctat agcatgttct ccattcactt
    17041 caatatcctt atttagtatt ctaatatcat tttcagtata aattcctatt gcatcttttc
    17101 catttgcctt tattttttca acagattcgt aggatgattt aatatgtaag tctcctcctt
    17161 cttcaacgta taaggctgtc ccatcagtag caattatgtt gtttatacca atacttatac
    17221 ttccaccatt ttctatatgt attactcctt cttttcctcc ttcacctatt atattcaatt
    17281 cattatcatc aataataaat ctcccatgat tttttatcaa tattttatat ttgttggtat
    17341 ctattgtaaa attactgtca taaggaatat aaaatctaaa ctcttcatct attaccatat
    17401 cacaagaaag agtataaact atttcttctt tattattttt attttcttga acccaccttt
    17461 caaaatcttc aagacaattt tcctcttgtc caaaaacttt atgtggaaaa cttataaaac
    17521 acaaaactat tatactcata aaaataaata tctcatactt tttcatctta cactcctaga
    17581 aatttttagc tttgaaacaa tcctgtcgaa acatatactt cacccactat aatttttcca
    17641 caattatcaa ttattgtcaa tttatataag tatctttatt aattgttata aataaaaagc
    17701 tacttactaa agcaaacaga cgtttcactt taataagtag ctatattttt ataacaaaat
    17761 agttataata ttagaacttc cttcatttac aattttttgt aaagtctttt gcattttaac
    17821 tcttatctct tctggcatag tatataattt actttgtaat tgctctttta ctaagtcatg
    17881 tagtgattta ccaaacatat ttgattccca taaatctgct ggttgctctt caaatacttc
    17941 cataagatat tttatcatct cttcaccttg attttgattt ccaactattg gagaaacctc
    18001 tgtagatata tctgctttta taatatgaag tgatggtgca ttggctttta acttgatacc
    18061 atattgtttt ccttgtttca ttatttctgg ttcttccaga ctaagttctt ctaaggaagg
    18121 agctactact ccatatcctt ttatcttggc atctattaaa gcactttcta ttttatcata
    18181 ctcattttta actttagata gtctagttat cagactaagc agttgataat ctccttcaat
    18241 tttaaatcca cttttttctt caaggacatt atagaataaa tcttgctttg tctgtaaatc
    18301 aatatttata acaccttctc ctagctctac attatcaaca cctgtatctt ccaaaaactc
    18361 taactcagaa aatccttgta taataccttc tatatccctt attttaccta tatctataat
    18421 actttgtttt aatgttgtta ttatgctact ttttatccaa tgatttcttt caagaccttc
    18481 aacccatttt ggtaagttga ttcttatttc tgtaagtgga aaatcatata atacagcttc
    18541 cataacctcc tctatatctt cttcttccat ttcaaccaca ttcattggaa gaactggaac
    18601 ttcatacttt tcttccaatt cacttctaag catactcgtt tcctcacttt ttggacttaa
    18661 cgtatttaaa accactgcaa atggtttttt aagatttttc aattcttgta taactctctc
    18721 ttctggttct acatagcttt ttctatcaat tccagtaact gaaccatctg tcaagacaac
    18781 tatccctatt gtagaatggt cttttataac ttttttagtt cctatctctg ctgccttttc
    18841 aaatgtcata gcttcttgtg accaaggagt ggatactaat ctttgttttc caccttcctc
    18901 atgccctaaa gctccttcaa ctatgtatcc aacacaatct accattctta cttttaaaga
    18961 tactgtgtct tttattttta tttctacacc atctgctggt acaaattttg gttctactgt
    19021 cattatcgtt ttacctgaac cactttgggg tatctcatct cttgttctat cctttttaaa
    19081 ttcattgtct atattaggta taaccaactt ttccataaat tttcttataa aagttgattt
    19141 tcctgttctt acaggtccaa ctactccaat atatatatcc ccctgagtcc ttttggatat
    19201 atcttcgtat atgttattat tcatattatt cctcctatac atctaatctt attaaattat
    19261 atttagagtt aagggttaat attcttaaaa tagaaaaata aagaccagca atattaattt
    19321 aatttacata tagaaatttg taaatttcaa tgtaaattaa attaatattg ctggtccaaa
    19381 tagtagtgta ttatattaac tgactttagt agcattttca tttgaattat tattcatctc
    19441 aataagttct ttacgtcttt cttttgtcat gttcatccat ataaatgtaa acaccaatcc
    19501 aattatggct actatagtaa gaactatgaa gtagtaccta tatccagtta cacccggaaa
    19561 tgcatccaat atcttccctg ctgctaaagg acaaagtact tctggaagat atcctaacgt
    19621 agcaactatt cctatagcag ttcctgatat tgataatgaa taattacctt cttcaagtaa
    19681 cgaatagtgt aaaccttgaa ttgcatacat agatacatat attgcaacac atccaatcaa
    19741 tagtatataa accatagatg attttgttgg tgtaaatatt acacctaaaa gacctgcaat
    19801 cataagtata aatccataag atataatctt tgatgaacca actttatctc caagtaatcc
    19861 agaagcagct gatgctattg gtctacaata ctgagctaat attgagattg cagatgcaaa
    19921 caccacagta gctccaaatg cttcagttga ataaggcgta aaataataaa atgacatatt
    19981 agctgaatat gaacaaaaca ttattattgt tattatccat gtatgaggca tttttattac
    20041 tgcaaaaaag gcttctttat caaattttgc tgatacctct ttttcattat cctttaattt
    20101 gaaaaatact aatactccaa ctattacatt tattactgag tataatacta taatagctgt
    20161 aagaccagat ttatcactta cttttgatga aatataccca aatagtatca atactagaga
    20221 tagatgaatt gcattggtaa ttccacgacc actttccata aatccaaaag cttttccttg
    20281 ttcattttca gatgctaaca ttctaacagc ttttacaaga gctggccaaa aagtaagtat
    20341 tgttgttatt ccccataagg catggattaa aaacacaaca atatatggag gataaagtgt
    20401 taatacaaga ccagatattc ctgtaataat taaagaacct gaaagcaatt ttctggctga
    20461 aatacggtct gctaaaaaac caccaaaaag gtatgatacc attgcaagta gaccataaat
    20521 gcttcctaag cttcccattt gtgtatttgt aagattaaat gcttgtgcaa aagtatcata
    20581 ataataattc tttaaatacg gtaaagcata tataaatgct cctgctacaa agagtattat
    20641 caagactttg aaatttttcc aaatgcttgg tttatttact tcaactgaca tacttcctcc
    20701 ttatgtaaat acctgtaaat tttcatgata attaattatt gcttattgta ttgtttattc
    20761 aatatttcgg aatatttatt aatatattag gttaatctat ctctaatata agatgtaaaa
    20821 agcaagacat atggaaataa tgctgttaat gctgtcatag taacaagaac attgtatata
    20881 ttatctactg atggtaataa gtttgttcct acaagaagta gactcactat tatagcctga
    20941 actattactg catttgatgg tatattgtat ttatttgtaa cagtcaattg cttaggaaat
    21001 acaccttctc ttacatttcc aaaaagcatc tttactggac ctgctatata aagtattaat
    21061 gctcctagta ctgataaagt tattccaaat gctactattc ttataaacca acttcctata
    21121 cctaaatctt gtgcaacttt agctaatgca tctagtatcc ctgtagatgc tgcaatttta
    21181 tctggaggaa gtatcattgt tattgctact gaacctaaga tatagattcc tcctattaaa
    21241 acagccacag ttaatatagc tttaggaaag tttttcttag cattatccat ttcggttatg
    21301 aaattagcag tcgtttcagc tcctgataat gcaaatatta tagcagatat agaaactaat
    21361 gaattggcat ctatttttgg tattatattt tggattgtat atatcgatgc tgatggagct
    21421 tttttgagaa taactacaga cataaatgcc atcactataa gtaatatagc aggaattgta
    21481 gaacctaatg ctcctgtatt cgtaaaaaat tttccaaatg ccatcccacg agtacttact
    21541 aaggacaaca gccaaaatat tatgagtgaa agtgctaaaa taaacatctt attgtttgat
    21601 aaatctggat ttccaagcat atatgcaata tttatcgcta aaaaagtcaa gaaagaagaa
    21661 taccaaaata tctttgatgt ccaatttagc catgacacca taaatcccca cttctctcca
    21721 taagcttgtt taacccattc tccaagtcca ccattttttg gatatgttgc agccaactct
    21781 gcacatataa gtgatgcagg aacaaagaat ataaaagcaa acaataacca aactggtata
    21841 gaaccaagac ccaatccaaa actagaggca gtagatttag ctatccatct aatcccaaat
    21901 agtgctgata tattcataaa tactaaatcc caaaatccaa ttttcttttt cactgtaatt
    21961 cctccaattt caaatttatt cagactcata cacaatgtat tgacttaaat atcaagtata
    22021 agttcttcaa cacttcttgg ataattagtt ataattgtag caccattctt acctactatt
    22081 gctgtatctg agtgtctaaa tcctccaact ccaggtatat atatccctgg ctccatagaa
    22141 aataccattc cttcttctaa tattaattca ttgtcaaatc ttaaatatgg ctcttcatgt
    22201 tctgataaac ctaaaccatg accaattcta tgatttgaat ataactctag accatacttt
    22261 gcaacaacag ctcttgctgc ttcatccacc attcttgctg gtataccagc ttttattgta
    22321 tctaatccag cttgttgagc ctctactgca atcttaaaca cttctttttg tctttctgtt
    22381 ggtttgccta taataaaagt tctttcattt tctgctctat agttttcata ccaaacctgt
    22441 ctactatgta ttactatatc tcctctttga agtattctag tattggaatc taaatgaggt
    22501 tgtgctgttc tatcaatccc tgaacaagtc cagtttgcaa atcctatata tgtatcagga
    22561 taattttcag aaacatattt tagtaaagca ttatcccctg caacgtcaaa ctccaattca
    22621 ctcatcccaa ctctaacatt ttctaaagac ccttttattc ctatatcaga taggtaacct
    22681 gctatcttca aaaattctat ttcttttgta tcttttacat atctcatttc aaatatttta
    22741 cttccaacat ctttgatagc aaatgactta tcagttatat actctgaaaa gcttgcagat
    22801 actatatctt tttctattcc aacagttgtt cctttagggt atttatttaa aattatatct
    22861 aagtaatgtt tatgtgatat tccatgttct ttcatttctg gtatttcata atacacatat
    22921 acattatcaa cttttgcaac ttctttagca tgtaattctt ctaatccagg tactattaat
    22981 tctattttat cttgagttac tactgttaca attggtctag aataagttat tgctttaaat
    23041 ccactaatat aaaattgatt gtctggttca aatattaaag caatttcaat gcttttttca
    23101 ttcatgtact ttctcaatct ttctagtctc atattatttg acataatgca cctctttctt
    23161 aatattcaga taatttattc aatacaacaa ggatgaatat attattttaa aattcttaat
    23221 atttttagta cttgtcgtat ttgtatgtaa attaatttta tttgtgatta ttttatcata
    23281 atcatgatta ttttgtcaat catgatttta ttttaaaaaa ttttttatat tctagtgatt
    23341 ttaaattatc taaaatataa cgagtataca ttgtattttg taatattatt cttgatttat
    23401 ggtaagttta atgataaaat cacgattata taaactatat tgattatttg taggtgaata
    23461 aaatgacaaa taaagaatta caaaagaaaa ggatattgat gtatttcata gaagctgctc
    23521 aaaatattat ggaaaacgaa ggtatagaaa atattacact tcgtaatgtt gcagatatgg
    23581 ctggctataa tagttcaact ctatataaat actttaaaaa tttagaccat ttaatatcat
    23641 ttgcatctat aaaatatttt aaagattata acttgaatat ttcaagatgt atagaaaatg
    23701 tcaatgatga atataagaaa tatataatta tgtggaaatt attttgtaag cattcttttg
    23761 ataatgctca agctttttac caggtatttt ttaacttgtc tagtgatgaa cttagctata
    23821 taacaaaaca atattatgat atgtttccag aagatttagg tattcatgat agtgacatat
    23881 ctttaatgat tacaggagaa agtataaagg aaagaaataa gatactatta aacaatcttg
    23941 tagatactgg atatatacca gctaaagatt tagacataat caatgatata attatttctt
    24001 tttatcaaaa tctattattc ttaaaaaaga acacaggaaa aaattctgat gatgatgaat
    24061 taactatgaa aatgatttct tctattgaat acataataaa acatgctaaa taaaattaaa
    24121 atatggctgt ctcaaaatag agataagcct tttttattgt tgaaataata aaaatatatt
    24181 taatttcata taaaaaagag tgcctcgtaa actaaaaagt tcattttgag acacccctaa
    24241 aataaattta ttatttatta tacaatagtt tatatatcat cacctaaaac tacttcttcc
    24301 atttcatgct ttttacttct catcattagt tctattccaa cttctttagg atttgaacct
    24361 ttctttatta cagaatatat agcattagtt ataggcatat ctatatctaa tttttcagca
    24421 acatcatgtg ctacttcagt agcagttatg ccttctacaa ccatctttac ttcttttaaa
    24481 gtatcttcta aactcatccc tttacctatg agtataccag ctcttctatt tctactatgc
    24541 atacttgtac aagtaactat taaatctcca atacctgaaa gacctgcaaa ggtagacata
    24601 ttagctccca tagcaattcc aagtctgctc atttcactaa tacctcttgt cataagggca
    24661 gcttttgcat tatcaccata ccctaatccg tcacatatcc cagctccaaa tgctataata
    24721 ttttttaatg ctcctccaag ttctactcca actatgtctg gattcgtata aactctaagt
    24781 ttagggctca taaataaatc ttgtatcatc tgtgctattt ttaaatcttt agaagcaact
    24841 actacggtag taggaatatc ccttgctact tcttcagcat gagatggccc agatagtatt
    24901 acatatggat tttgtggtaa ttcttcttca cagacttgag ataatctaag cccagtccct
    24961 ttttcaagac ctttagctac attaacaata acttgtcctt cttttataaa tggttttatt
    25021 ttttggcaag tacttcttac agcctgtgat ggaactgcta aaactattac cttacaatct
    25081 tttatagttt tttctatatc agtacttata gttatattat ttggaaataa tactcctggt
    25141 aaatagtctg tattttcttt agttctgttt atttttttag cttgttcctc ttttcgagtc
    25201 cacatgctca catcattacc tttttttgca agccctaaag ctaatgcact tccccagctt
    25261 ccagtaccta atacacatac tttctccatg tttaacacca cctgagtata atatatttac
    25321 tattctttct tttgaccaat ttttctctct gtcccattta ataatcgctt tatatttgct
    25381 ctgtgattat atattactga tgcagttaag aacagagcta ctattaaacc agctttattt
    25441 tttaccataa tcataaatat tggtgaacat cctattccta caacagaacc caatgaaaca
    25501 tactttgtta tagctaccac caatataaat actgctagac acattagtgt tattactgga
    25561 tttacagcta gcattgcccc tagtgaagtt gcaacacctt tgcctcctct aaatcctaaa
    25621 accgctggcc aattatgacc tgctacaaca catataactg ccagatatcc agctaaaaga
    25681 gtatctattc caaccaatct tgctgcaaat tctgatatta aaacagccat tacaccttta
    25741 agaacatcac ctaaaaatgt cattgctcct gctctttttc caagtgtcct aagtacattt
    25801 gtcgaacctg cattaccaga accttgagtc cttatatcaa ccccagcaat tcgctttgca
    25861 actatgtatg aggtagatat atttcctaaa agatatgcaa ctacagcaat aattatataa
    25921 ctaaatatct ccactgaatt tccccccttt agttatattt taagatattt attttttatt
    25981 tttttgtcta tactcaaact ttatggaagt tccttcaaat ccaaaatttt ctcttatctt
    26041 attctcaagg tatctttgat atgagaagta agttaaatcc ttatcattta taaacaatgt
    26101 aattttagga ggtctaatgt cagtttgagt cccatagtaa atttttaatc ttctaccttt
    26161 gtcagatggt ggttgattta acattacagc ttctccaatt acttcattca gtgctgaagt
    26221 tgatattctc ttagaatgtt catttgacac atattcaact gtatctagta tcttgttcat
    26281 tctttgatta gtttttgcag aaacaaatac gattggagca tacatcataa atggaaattt
    26341 ttcttttata tcttttgtgt aattactcat agtcttatta tctttctcta ttaaatccca
    26401 tttattgatt acaaatatgc atccttttcc ttcatcatgt gctatacctg caacctttgt
    26461 atcttgttct gttacacctt ctaaggcatc tattactatc aatactacat ctgctctatc
    26521 tacagcactc atagctctta ttacactgta tttttctatt gtctcatata ttttactttt
    26581 tcttctaagc cctgctgtat ctattagaag aaatttctgt ccattttttt caaaataagt
    26641 atcaattgcg tctctagtag ttcctgcaat tggacttaca attactcttt cttctccaag
    26701 tatcttattg agtatagaac tttttcctgc atttggttta cctgttatag ctactcttat
    26761 tatatcttct tcatactctg tatctaatcc tgctggaaaa ttttcaacta tctcatctaa
    26821 taaatctcca aatcccatac tattggctcc tgaaactgca aaaggcgttc caaatcccaa
    26881 ctcataaaaa tcgtatatat tatcaaattg actttgacta tcaatcttat taaccactaa
    26941 gattactggt ttttttgtct ttctaagcaa ttgtgcaatt tctttatcag cagctgttat
    27001 tccagcttta ccatcaacta taaaaagtat tacatgtgac atgtccattg caagcatggc
    27061 ttgatttctc atttgagata atattatatc ttcgctatca ggttcaattc ctcctgtatc
    27121 cactaatgta aaatatttat ctaaccattc tacttcagca aatattctat ctcttgtaac
    27181 tccaggtgta ttttcaacta ttgatatcct ttttcctgca aatttattaa atattgtaga
    27241 cttaccaacg tttggtctcc caactacagc tacaactggc ctacttatac tcattttatt
    27301 tctccttcca tcttttgttt tctattttaa aattttatcc acaaaatctt ttccttcatt
    27361 caaacaaggg ataattttta ttctcataag ttcttctaat tgatttaatt caatattatc
    27421 taagaaaatt tcttcatctg cttttagcat acttcttgtt atataaagag cttctcctaa
    27481 ttctttatct tcaagttgtt cttttaaatc cttagctgtt aaaagacctg atacagttat
    27541 tgtctctcca aaaaacttgt ttttgatttc atatacattt acttgaagat ttttaaactt
    27601 gtccatcata gcatctgcca tactctgtat aaattcatat gcagaatgac cagtagctat
    27661 tgatactttc ttctctcttt ttagaatctt ctcaggcaat atatttagat actcttcaat
    27721 ctctgttttt aacttacgta tcatacctac accatcttca aactgtaaaa aaccttcata
    27781 ttcttcatat ccaggcaatt cactattaga tagtatataa aattcatctg ataaaaatgc
    27841 aaatcgagta cctaattttt caagatattt ctgttgtatt tgatgtattt gctctatagt
    27901 tttacttgcg ctcttatcat taaatatatt taattctact agattttctc tatgctttgt
    27961 aatcccaact ggaactatcg caacactgtt tacatacgga taaagttgag ctagttcttt
    28021 tattgttcta tccaattcct ttccatcatt tatacctgga cataaaacaa tttgacagtt
    28081 catttctata tgagcatctg ccaatctctt cattatacca tataattttc ctgcaaattt
    28141 attgcttatc attttttgtc ttaactctgg attagttgta tgcacagata tatttatagg
    28201 acttattcta tattttataa tattatttat atcttcttca ctcatatttg taagtgtgac
    28261 aaaatttcct tgtaaaaaag ataatctcga atcatcatct ttaaaataaa gagtttctct
    28321 cataccttct ggcaattggt ctataaaaca aaacatacac ttatttctac agcttttagc
    28381 ttggtcaatt atcggatttg taaattcaac acccaaatct tcatcatagt ctttttctat
    28441 ctcgtatatg tagacttcgc catctttttt ttgtatttct acatctaaat attcatcact
    28501 tagtaagaat ctatactcta ttatatcatg tattggctgt tcattcacag atataagtaa
    28561 atctcctacc tctataccca tttcttctgc aatactatct ttataaacct tacttataat
    28621 attatttact ttttttacat ttacttccaa tattttcacc actcttttgt attcatcaat
    28681 gcttattata atgtatttta atatgcaatt tatttattta ttatatttta tgatagcatt
    28741 tttaagcatt tcatgtcata ataacacatt ttaattctaa tagtcaatat aagtaaatag
    28801 ctataaaata gattagaaca aataatattc aaatttaagt ttcttaaaaa tttaaatatt
    28861 atttgttctt aaaaaaattt tataaattta atgttttact atgattaacg tcccatttgt
    28921 catatcatga accattccac ctacacactt tgacatcaac aatgccttat tttgtaagtc
    28981 tttctcatca tttgcataaa atattggaca acctccacca tttttcatat tcttatcaag
    29041 tgtaactata gctagggtat attcatttaa acctatatcc attcccatct tatgcacttc
    29101 ctttctttcc tattttataa ttttttagtg ataagttttt tcctttagag cttgaaagta
    29161 ttgggcatga ctttacagct tccattactt tttccacatt cttatctact ggtaaataag
    29221 caatcattat actttcatcc tctttatttc ttctaggtaa tggtacgaat gaaggttctc
    29281 cataatctcc atataaacct aaccttgaat atatattgta tactattgct tgtctttgac
    29341 cggagtcaaa taatattcct gcattagcat aatccttatt tttaggaatt atttgtattc
    29401 ctacacctct attaatatat acttctctat cactttttag acctatattt gttattccct
    29461 ttaaatctcc taccttcaat atagactcat ctacaaaact aatctcagca ggcattacat
    29521 cagctatgtc tccaatactt tttctagtaa gaagtttttt taatataaag gctaacacta
    29581 atccacaaat tgaacttatt accaaactca ttccttcact tattttcgtt tctgcaagta
    29641 ttacataata caatcctatt gttaaaaaag atgtaactat acacatataa tttcttactt
    29701 cataggttct agctatctct tctatgaatg cagctcctct ctttacaagt tgaacttcct
    29761 ctaagttttg caatgtattt cttctatttg ctctcacttg tctaaattgc tctgctgcta
    29821 gggataaaaa agttatagat gtataagaac gatttataag agctggaacc aataatgctc
    29881 ctaatgaaga agcgacgaat gctaatataa gttgagatag taaaacattt ggttgcgttg
    29941 gatactgttt ttggtctaaa ttcaacatta taattctaga tgttatacca ataataacag
    30001 caacaaaaaa tactctatcc attaaatcac tcctaaaata tttaatttga aattttacat
    30061 gtaaatctac aaagtctttc tagaaaaatc actctgcttt ccttttgatg tttctatgat
    30121 aggtgtactt ttcactacat ctatcatgac atctatatct ttgagtattg gcatatatgg
    30181 tataaccaca gtactttttt ctaaattggt cttagatata gcaacaatat caacctcatc
    30241 tacatctcta tctatcccca tatgaataaa tagattatgt attatagctt gtctttgccc
    30301 tatatcattt actattccaa atgcacctaa atctcttggt ataacttcta tagccagaca
    30361 ttcatttcta tacttttctc ttgtactttc tagacctatg ttagttatta ttacaccatt
    30421 taccattaaa ataggtcctt caaaacttat ttttgcagga actatatctg ctatatctgc
    30481 tatactgttc cttcttaaaa atcttctaaa aatcaaacca acaatagctc ctgacacaat
    30541 agctaagatt gtgcaataaa aaaagctaag gccatacttt cttgcaaaaa cgatataaac
    30601 tatcgaagat accagtgcag aaaaaagact tatataactt ctagattcat acgtagatgc
    30661 tatttcttca acgtaagcgt ctccttttgg tactaattct tcattatcga tattctttag
    30721 tgttattctt tcttgttctg caagaccttg aaactgttgt attgctactg caaaaaatgt
    30781 caaggctgca aactccttat ctataagtgc aggtaatgct atagcaccta acgaagctga
    30841 aagcccagat ataattatct gttctaaata atcttgtggt cttgatgggt attgtttgtc
    30901 tgtaactctt aaaactaatc ctctacataa tattcctaca actaatgcaa ctataaaaga
    30961 gtgtctaaat aaatttgcat tcaataaact ttcttccatt ttctcagctc cttctcttat
    31021 atagtttgtg caaaaaacaa aaaaaattcc cttctattta aggaaatttt tttgtaatat
    31081 tgtaactata aattcgctac caatgccaag ttcacttttt acttttatac atccatttag
    31141 tgatttgact atatgctttg ttatagccaa tcctaaaccc gttcctccta catccctact
    31201 tcttgcttta tctaccctat aaaatcgttc aaatatgcgt tctacatctt cttttggtat
    31261 ccctacacca ttgtctataa ctttaattac gattttttct tcatctttta acactacaac
    31321 ttgtacaatc ccattatctt gggtatactt tatagcatta tcaactaggt ttaagaacac
    31381 ttgctttata tagtctttat tggatagtat acttattgat ttatcatcac atttatataa
    31441 aacttctata tttttttcac tagctgaatg ttgagttatt tcatatacct ctttaaatac
    31501 atcatatact acaacatttt ccataagaag agtatcttta ttttctacaa atgataacag
    31561 caatatatca tcaatcaacc tttttaatct atctgattcg ctttctatta tttctaagaa
    31621 tctatttcta gtattcacat ctatattttc atttgacttt agtgtttcaa caaacccact
    31681 tatagatgta agtggtgttt taagttcatg acttacattt gcaacaaaat cacttctcat
    31741 attttcaagt ttaacttttt tagtaatatc ttctatattt actatcgaac ctattattac
    31801 gttgttagta ttctgaagat aaactgggtc tacttttatc ttatatacca tatcatcttt
    31861 agtagtaata ttagcagttt cattatcttt agaaccaata aattgaagta tttgttttaa
    31921 tatttcttct tcttttatta caacattaat attatgacct tcaactaatt gatttggttc
    31981 actctttatc atttcttttg cttcatcatt tatcagaagt atatttccat ttacatctat
    32041 agctaaaatt ccatgagata tactctttaa tatagacctt agctgtaaat gtttatactg
    32101 tacttcttct aaggttttat ccatattctt tatcatatga ttaaaatttc tagctaattc
    32161 gccaagttct cctttggctg atatgttaag cctagcatga tattcattat tacttacttt
    32221 ttttgagacg tatataaact cttttaaata tttccttaat gttattgtgt atcttacagc
    32281 taatataaca atggctatgg acaacataac aataaaaaaa tatatactat ttaaatcttc
    32341 cacaagataa cactcctaaa atataacctt tttaatctat tttgtatcct acacctctta
    32401 tagtctctat atatttttcc gatttatctt catcttctat tttttttctt aaatatctta
    32461 tatgaacatc tactgttcta gtttctccat agtattcata cccccatatt ttatccaaaa
    32521 gataatttct tgaaagtact tttcctttat tttgaattaa taattttaac aattcaaatt
    32581 ccttaagagt taactctatc ttttcagagc ctttggtaac ttcatgtttt gataaatcta
    32641 gttttaaatt acctgtagta agtatattgt tttcttcacc taagctagtc aaattatatc
    32701 tccttaaaac agaactaatc ctagctaaca actcttttat actaaatggc ttagttatat
    32761 agtcatcagc acctatttca agcccttcaa ccttgtcatt ttccatattt ttagcagtaa
    32821 gcattataac aggaatattt tttaagtcct tatcacttct tatttttctc aaaacttcta
    32881 ttccacttat atttggtaac atccaatcta aaagtattaa atctggttta atttccttag
    32941 cctttataaa tccgtcaaat ccatcatatg aataactaac ttcgtaattt gacacctcca
    33001 aattgaattt taatagctca actatatgca tttcatcgtc tataacaagc actttagtat
    33061 tcattaaaaa gctcctctct attttatctg tagtaccgtt cctattcgtt ctgatgcctt
    33121 attatgtttt ctataagagt ggaatttatc tgctctacaa ctagtgcata aatttaaatt
    33181 tattatattt tcttttttaa ctccactaca tctaagcata tactcattaa ttttccataa
    33241 atctaaatag taacttccct cttttattat atagaacttt tcatcattat ttgtaagaat
    33301 tgtgttaaat ttttctacta aatcttcaga cacttcataa caacatggtc caattgatgg
    33361 cccaattata catactaaat cttcaggaac tgttttatag cattcagaca ttaattttat
    33421 tgttttatga cctatattac taaaagtccc tctccaacct gcatgagcca gtcctatggc
    33481 tttattttta gcatctataa ttgatatagg tacacagtct gctgtaaaca gtaaaagtgg
    33541 tactttttcc aagtttgtta taagtgcatc tccatctctt cttttcccta tagtatcttt
    33601 attgactata ttaactatat ctgaatgtat ttgagaatta ctagttagat tttcaaatgt
    33661 caaatcacat tctttacata cttttaacat atcttctcta ttttttgcat ctatattctt
    33721 acatgttata actagattta cagaatttaa tttttcatca agttcttcac aattaccact
    33781 taaattaaca tactctttaa tatcttgtac attttttata tttatataat ctttcatcat
    33841 ttgtctcctt tttctatcag tatactttta agttcattta caaaagtatt tatatcttta
    33901 aattgtctat acacagaagc aaatcttaca taggcaacct catctaactc tttcaattta
    33961 tccattacca tctcaccgat ttttttggtt tcaatttctt ctataaaaca tttatttatt
    34021 tcattttcaa tatgtacaac aatactttca atctcgtcaa tagaaacagg tcttttttca
    34081 catgctttta gcaatccata ttttatcttt tctctatcaa aatattctct actattatcc
    34141 tttttaatga ccattaaagg agttgtttct attttctcat acgtagtaaa cctcttttta
    34201 catgattcac actcacgtct tcttctgata gattttaaat ctgtatgtct agaatctatt
    34261 acctttgatt ctttataatt acaataagga cattgcatct atattcctcc tttgtttaac
    34321 tatatctcaa actcatctaa gcttaattct gaacctatat ttactattat tgtatcacaa
    34381 cctattttaa gtatatcatt ccaaaatata acttcttcat cccctcctct tgaaaaaaaa
    34441 cttctacttc catctccaaa aatggtaaat gagactacct taccttcgtg aatatccatg
    34501 tctatgtcta ttataaaccc catccttttt ccatttttta catttataat ttctttttcc
    34561 attatatcag aaactctaat catattgtac tcaccctttc tttaaaaata aatatgtatc
    34621 gaagtaaaaa aaaatgacct atataggtca tttaaattaa aataatgttt acagtccatg
    34681 gattacttat acatattttc tcatattctt taaagcattt ttttcaattc ttgatacttg
    34741 tgcttgagat ataccgattt catcagcaac ttctatctga gttcttcctt tgtaaaacct
    34801 taaatctaat accaactttt ctctactatt taatttctta atagcttctt taagtgatat
    34861 ttcttgcaac caattttcat cagtatcttt tttatcttga acctgatcca taacgaatat
    34921 tgcatctcca ttgtcttgat atactgggtc aaacagagat attgggtctt gtatggcatc
    34981 aagtgccatt acaactgatt ctacttctaa ttctaattcc tttgctattt ctgatactgt
    35041 aggttcttta gaatttgttc taattaatct ttctctaact tgtagtgcct tatatgctat
    35101 atcttttaat gacctactta ctctaattgg gttattgtct cttagatacc ttctaatttc
    35161 tcctataatc ataggaacag cataagttga aaaccttaca ttttggctta aatcaaagtt
    35221 atctatagct tttataagac caatacaacc tatttgaaat aaatcgtcta tattttctcc
    35281 tctgttgtta aactttttta ttacactcaa gactaatctt aaattccctc ttacaaactg
    35341 ttgtctggct tcttcatcac cattttttat ttgtaataaa agttccttca tttgcttatt
    35401 tttaagaact ggaagttctg atgtattaac accacatatt tcaaccttat taacttgcat
    35461 atattttcag tcctctctca aaagtattca tctattgaaa ttatttacat ttccaatttt
    35521 tttatacttt ttaagaagaa ttaatttagc attatacaaa ttttttcatt tctttttgca
    35581 accttgagat tattttcttt tcaagtctag atatgtagga ctgtgatatt ccaagcattc
    35641 cagcaacttc tttttgtgtt ttttcaatac ctttatcaat aagaccaaat cttaattcca
    35701 taatttgctt ttctctgtca cttaatctgt caagtgccat aaccaacaaa tctctatcta
    35761 tttcttcttc aattattttg tatatttcat cattttctgt acccaataca tcagataata
    35821 aaagttcgtt tccatctaaa tctatattta aaggttcatc aaatgatact tctgttttct
    35881 ttttattatt ttttcttaag tacattaata tttcattttc tatacatctc gaagcataag
    35941 ttgccaattt tatattttta ttcagtttaa aagtattaac tgcttttatc aaacctatag
    36001 ttcctattga aatcaaatct tctacatcta tacctgtatt ttcaaatttt ctcgatatgt
    36061 agactactaa tctaagattt ctttctatta aaattgactt tacactttca tctgtttcta
    36121 gcttttgtaa aagctccatt tcttcttctg gtttcaatgg aggaggaagt atatttgccc
    36181 ctcccatata gtatattccc tttggcttta ttatttttaa tttaatacct aacatagtaa
    36241 taaagcttat tattctttct ttcaatcgta acattccttg tcccccttaa attttcacct
    36301 aaaatccagg caatatattt ggattcatta ttgctccata ttctctatca ttaaaatttg
    36361 aaataccaag tattatattt cctatctttt gctcatctac ttctatatag tcagctttta
    36421 agcctattat tatgcttgtc ttattacttc cagcatgttt ataaggtatt attctaactc
    36481 tacctgaagt tttatcatct aaactcccta taatttcttg tgctttcttc atatctatat
    36541 cttcataatt aatatttaat agtttttctg gaataaatcc ttctaacaca ctagacttaa
    36601 ctattattac atcactttga cttattgggt cttttaacaa attaccacta tctactaaag
    36661 ctttacagca aaaacttttt tctagtaagt ttatatttat agtctttgta agctccttaa
    36721 tgtacttaag cattttcaaa tctttataaa tgtattttaa taattcacaa ctcacataag
    36781 tacatgcaat taagaaagat atttttaagt gacttattcc tgtaaaataa attataaaat
    36841 aagtgcttcc agaaataaaa atgtttacta gataaaaaac taacgctaca tgaacataat
    36901 cttttttgct cttacttcta aatgaaatta aagttattat actcatgatt attattttaa
    36961 atggtacagt aaatagtata ttcattgatg gatacaaata agcaacagaa taggcacctc
    37021 ctaaactagc ccccaataac ttattttttt taggattata tcttttagta agaatagaag
    37081 tacaacttat aataatataa tttattacta ggttttctat aacatagtac tcaatataca
    37141 ccatgtatcc ccccttaaaa cctttaaaca tattataaga tagtatgtac aaaattttat
    37201 gtcacttttg atggtcgaat ccaaaacaaa ttctatttaa aaagaacaat gatatatgtc
    37261 ttatacttta tgtcgtcaaa agatattttt ttaatgccaa acaaatagac ttttttgtag
    37321 aatccaatat atctaggtag aagttattcg ctctactttt ggtatattta caaaaaaaga
    37381 ctacataatt taataatata tcaagtaaat cttttactta tataaaatca aattatatag
    37441 tctgtaaatt caaatataaa ttattgtgct agtaatccat ttgcatattt tgcagattca
    37501 tttagtgctt gttctggagt tatgtctcca gctatcatca tttgaagttg tttccataaa
    37561 tattcatata tctctactcc atgaggtcca actgtcaatg gtctatacat atgtttatct
    37621 cttgtcacca tttcttcaaa tcttgggtct ccttggtatt tttcaccttt agcaactgga
    37681 gctctaggta tttctttgtg gaaagcttcc attgattctt tgcttagcat atactcaaga
    37741 agtttaaatc caagttcttt atttttacat gctgacatta atgttaaatc atctactgaa
    37801 gcaaaacttc caactgtctt atcttctaat gatgttacat atccccagtt taaatccggg
    37861 aatgatttat caaatgtact tgtagcagca gaggatagca ttatagtaaa tgcagctttt
    37921 cctggtccaa atacactttc aatcatttca ttactatctt ttgataaagc atcttctgga
    37981 atatactttt tcatatcatt tataaagttt gcagctttca agccttctgc attattaaat
    38041 ttaactgatt ttaaatcatc attatatata tctccaccag cttgccataa atacggatac
    38101 cagttccagt ttaagcttcc aaatacttta gaaccccaac cttgtgcaag accccactgg
    38161 tcgatttttc catctccatc agtatctttt gttgcttttt cacagattct tttaaaatca
    38221 tcccatgttt ttggaggttt ttctcctaat ttttctagta tatctttatt gtagtacaat
    38281 acgcctggat tagcagcttc tataggtaaa ccataaatac cacccatcat ttttgcatca
    38341 tctaagtata gataattatc tgaagttcct gatttttcta aataaggtgt taaatcttct
    38401 accgcaccca tttctataaa ttgaggaaac atctctgcat acatgtatcc tatatctgga
    38461 ccttcacctg cacttattgc tgttgcatat ttttctgcgt agttatccca tggtactatc
    38521 tgaaattcaa tttcacagtt attttctttt tcaaattttt caaatatcgg cttccatgca
    38581 tctgcatcat ggtctgttaa tggtgcagac catacaacta atttttcttt accctctttg
    38641 cctttagaat cttctttttt tgaacatcct gcaagaattg atactgatag aatccctacc
    38701 ataactaaag aaagaacctt ttttagttta atcatgctta atcccctttc agactttaat
    38761 ttgtcttttt cctcaaatgt ttacatttaa ttcagattta atattaacaa ataagattac
    38821 tcttgtctaa tcataaaaaa ctatactaac tcctataact atattttttt tctataccta
    38881 ttagatttaa ttcatactaa aaacttactt tttaaatttt atcaatattt aaaaattttt
    38941 ttaagtctag ccacaaacta actatctaaa ttgagcaaaa taaaaagaag tctattgact
    39001 tctttataag cttacatatt atcttcttct tcttaggaat gtaggtatct ccatgctctc
    39061 atcatcatct tcttcaatta tacttgcctt tttaggaggc tctatttttt cctcagcaat
    39121 tacttcttct tcaatttctt ttacagcttg ttttactgtt gtatttaatg aagaacgtat
    39181 gcttgattta ggtttagtat ctaaatctaa ggcaccattt tgtaatcctt caaatcctgt
    39241 cgcgattact gtaatcatta tttcatcacc taaatcttct tttatagaag ctccaaatat
    39301 aacatttgct tctgggtcac aggattccat aactaaagtt gatgcctcat taacttcaaa
    39361 taatcctaag ttaggaccac ctgtaacatt aagaagtact cctttagctc cttgtattga
    39421 tgtttctaga agtggagatt gaatagcttg tcttgcagca tcaattgctc tagtttcacc
    39481 actagcacta cctataccca tatgagcaag tcccttgtct ttcattatag tagtaacatc
    39541 tgcaaagtcc aagtttatta acccttcaac tgctataagg tctgaaattg attgtatacc
    39601 ttgttttaat acatcatctg caactgcaaa agcatctaac attgatgtat ttttttgtac
    39661 tatctgtaaa agtctatcat ttggtatcgt tataagagta tctacttttg atttaagttc
    39721 tgctattcca ccttcagcgt tcttcattct tatcttacct tcaaatgcaa aaggtttggt
    39781 aactacacct actgtaagta tccccatttc ttttgccaag cctgcaacca ctggagcagc
    39841 tcctgtacca gtaccaccgc ccattccggc tgttacaaag accatatcag ctccttgaag
    39901 taactttact atttcatctt tactctcctc agcagctctt ttccctactt ctggatttgc
    39961 tcctgctcca agtcctctag ttaatttttc tcctatttga actttatatt cagcttttga
    40021 tgtatataaa gcttgtttat ctgtatttac tgatataaat tcaacgcctt ttagttgagc
    40081 ttctaccatt ctattgacag cattgtttcc accgccacct acacctatta ctttaatttg
    40141 tgcacattct tctaattcta cgtcaaagtt tagcatcata aacccccttc tctcatgatt
    40201 caaagttatc gtatgtatta attatatcat tttcttcttt tattttgtta acctttaagt
    40261 aacatattcc acaaaaacgt aaattttcct ttttaaattt cttacttata ttgtcaaata
    40321 ttactcttta agtataaaat aatttacgta tatattaaat gctctttaat ttttacgttt
    40381 tttgttcata atattactaa taatatatcg tctaattata gataagttat taaacaatct
    40441 cataccaaaa actaatacag caacatagta aagagaaact cctaactttt ctcctatata
    40501 agtcaataat atagccaata tagcattccc tatgaaacca gtaataaaaa ttacattatc
    40561 atagttatct tcaaaattgg attttatcgc tccaaaaata gaatccatta ttgcaagaat
    40621 agctactgac atatatatgg aataatccat agaatatgta aatggaatat agtaacctac
    40681 tactacacca aatgctaatc ctcctaaaac ccataacata aatcttcacc tctttatttt
    40741 actttgaaac acaactacat tacaatcctt tttattaatt ttttttactt tttctttatt
    40801 tttttgtatt tttcgtttta ttttgcaaat aaatccactt tatttccatt attttcctga
    40861 acttttatat taattccata tatatcctta agagatttag catatgattc tggagagttt
    40921 atagctgcac tcaataaatc tatatctcct atagctttta ttataaatgg ttgtccatat
    40981 gtagtatcat ttactgtaat agtagctcct gaacatttta tcttacttgt tgctagtact
    41041 ctttctccat ttatagaaat tgctcttgct ccagcctttt ttaaatcatt taaaaccctc
    41101 aaaatatcta tatcatgtat aatcaaatcg tttggattct gtccgtcttt taactctctc
    41161 tcactatccc tcatagtaat agttatgcct ggccctgtaa cagttgaata accacttaat
    41221 tctttaactt cttcaagctc tttttgcata agtgtttgga tagattcatt tccattcttt
    41281 tttgcttctt tatattcatt caaagttttt ttgttgtttt taagagtttc ttttaaattt
    41341 tttatttctt tttttgtatt ttctacctca ctttcaatac tttcagtttg acctaatgtt
    41401 atgtatactc tatttgggtc tagtgatttt atataagttg atatgaaaac gcctaatatg
    41461 aatgctccta atataactat tttctttttc atactattat ttcccctctg ctttgtttat
    41521 atcactatga ccatttattt ctatattgtc ttctttggtc acttttactt tggcattata
    41581 atatgtttct atttcccaga caataccata ctttatatta agtgccgaag ccaatgtatc
    41641 agaatcacca attgctttta ttataattgg ttcttttatg acagtgtcat tcatataaag
    41701 cttgtcttct tttaaataca tatatgtatt agaaactatt ctctggtcgt ttatagatat
    41761 ggcacttgct tgtgctgaat ttaatttatt tatcattgac aataataaat cataattata
    41821 tagtatacta tcatttttat cagagtttcc taagtctttt gtagaattta tctcaatttt
    41881 tatgcctgtt ccttcaacat ctgtatatcc agctaatgtt tcatattttt ctatttctga
    41941 cttaagtatg tcttgttctc cttcattgtt tttgcctcta taagtctcta tatctttctt
    42001 cacactatta acttctgatt gtagattctc tttttctttt tttaaagatt taagttcttc
    42061 tgtaagttgc tctcctcttt taaaagttgt catccctcta ttttctatat taataatttt
    42121 aagttgtaaa ctaacaagaa cacccaatac aatacttcct atgattatac ttttatttat
    42181 aaatcttttt ttcaatatat cacttcctta caattgtcta tccttctgga ctatacactg
    42241 ccaactttcc atagttaaga tttatagtcc ctccattagt atttttattt tgcaggtcaa
    42301 tcagaatttt acttacccta gatatattat aatctaagtt atcatcatta gaaagtaaga
    42361 tttttatatt acttcttgta agcatttcta tattgctttc tttttttaag tttacataat
    42421 ttatttttct ataaattcct tcttctttta aataatttaa agttttaaat acattctcct
    42481 tagttttata atttttaaat tttatagatt tattatcatc aatgctataa tctacatcta
    42541 ctatcaagtc ttttttactt tcattagaac ctcttagttc ttccaataaa tttccttttt
    42601 tatctatata acaataatta tcttcatctt ttaatactgc aaatatttct ttttctttta
    42661 aacttataat tatcttattg ggaagttttc tttttatttc cacattttct atatatggat
    42721 tttttataag tttatttttc atatctttaa aattgtatgc aaaaatattt tcatttagat
    42781 ttacatttag ttctttcatt atatttgatt tggtcaccct cttatttcca attacatcta
    42841 ttttctttac atcaaataaa tcacttttta caattataca tatacaaaaa gataacataa
    42901 gtataaaaac taaaactatc atgacattat tcgtatttaa ctttcttctt tttttcaaat
    42961 ataatcaacc cctttggtta ataaatacac ctttagagct tgtttttcct acaaaaaaat
    43021 tataatattt aaagtcaaat ttttgcattt tattacataa catccaaata aggtattaaa
    43081 ttttataaat aaatcaatat ttcatcaaaa taaacatagc atactacata ctatttatat
    43141 atttaaatct gtatacatac aaataaaccc ctaatttata ataatttaga aaatctaata
    43201 tattataaat taggggtaaa tatttactta tcttttcttt attcctatta ccttagcttg
    43261 accttctata cttggagtcg tttctttttt tatttctttt acttccttaa taactttttc
    43321 tttttttgtt tttttagaag ctgatttttg tgttgaattg tatactttca ttatctcatc
    43381 atatataagg tctatggctt caggcttacc tatagtttta cttgcatttg ccatatcaac
    43441 caaaagttct ctatctccta aaagtttaaa tactgctgta tttaggctct ctggagttag
    43501 atttttttct aaaatagcaa ttcctgcccc ttgtttttct atactcttgg cattatactc
    43561 ttgatgattt tcagcagtat aagctttagg tattattata gatggctttc caagagccgt
    43621 tatctcagct aatgaaattg ctcctgcgct acctataacc aaatcacttg ctgcaagtgc
    43681 atttgccata tcttctaagt aaggcacaac tttttggtat ggtttaagat ttatatcgct
    43741 aatacttccc ataaattcat cataatagct tttgcctgta gcaaatataa aagctatatc
    43801 ttcatttacc atattcttta ttacaagtct cattgcatca tttatttttc ttgaacctcc
    43861 actaccacca tagcaaagta ccattctttt ttcgtcactt attgatagat tctttcttgc
    43921 aatatttttt cttgataata aaatttcttt tctaactgga tttcctgtaa aaactaattt
    43981 atcttctgct gcctctggaa atcttttatg cgaatcttca aaacttgtaa gtacctttgt
    44041 aactgtttta gataaaatct tattagttac accaggaaaa gaattttgct catgtattat
    44101 ggctggtatt ttccccatag atgcattaaa taaaacaggt ccactaacat atccaccagt
    44161 tcctataact atatctggtt taaatttctt aacaatcttt cttgattgct ccaaaccttt
    44221 aaaaagctta aaaactcttt ttacattatc gaaatctatt tttcgcttaa aaccttgaac
    44281 tgttacagtc tttaattcaa atccatactt aggaactatt tctgactcta ttcccttttc
    44341 cgtcccaaca aaaattatct cagcgtctgg atgctcatct cttattttgt ttgcaatagc
    44401 tatagctgga tacacgtgcc ctccagttcc accgcctgat aataaaactt tcatcaaatc
    44461 atcatctcct gttaattaat tttgacatgc tttgagatgt ttaacactat tcctacagct
    44521 cccataaaga tggtgagtga agttcctcca taacttataa atggtagtgc tacacctgta
    44581 gctggcattg atgatgtcgc aactgctata tttaaagctg cttgtattcc aatttgtgca
    44641 cctataccta taacaaccat acaagcaaat acattagaag tcttcaaagc tattcttaca
    44701 catctataga ctaaaactac aaatagcata ataactatta tacaaccaat caatcctaac
    44761 tcttctccta ttatagcaaa tataaagtca ttttgtggct ctggtatata aaaatacttt
    44821 tgtttactct ttcccaagcc tagaccaaac aatccacctg aacctagtgc atatagacct
    44881 tgtattacct gatacccctt accaagaggg tcttgaaaag ggtctaaaaa tgatgtaaca
    44941 cgactaagtc tatagggttc agcaattact aatgcagcaa ataaagcagc cccactccct
    45001 atcatagcaa atacaatttt catatccatt ccagcaacaa atatcattac aaaagtaact
    45061 agaattacag tacctgctgt tgacaaattt ggctgaagta ttatcaacgc aaaaaatatc
    45121 cctggaacta cgagaagtgg tacaacacct tttgtcaaag attttatttt atcataattt
    45181 ttttcaatta attttgcagt taatattatt gtagcaaact ttgcgatttc tgcaggttga
    45241 aatgttaaag ctcctattcc caaccatctt tttgctccgt ttgcttctat ccctaaaggg
    45301 gtcaaaacta acaataataa tactactgct atagctccaa ttgctgtagc atttttcttc
    45361 caaaaactat aatctattct tgatgtaata atcataacta taaatccaag tacagcatat
    45421 attacattct tttttagaaa atagtacgca tcattgtgtt taaatgaaga ttgtataaaa
    45481 cttgcactaa acaccataac tattcctaca aatactaaaa gcatagtagt gtaaaacact
    45541 actccatcaa attcagtctt catccttatg tcaatttgtt ttttcaaatt ttctttaggc
    45601 atccaactaa tctacctcca ttcttccatt taagtaagtt tagaggtaag agattatttt
    45661 aaattgttta cattatcttt gaagtctttt cctcttactt caaaactttc atacatatcc
    45721 caacttgcac aagctggtga aagaagcact atatctccac tttttgaaat ttcataagaa
    45781 gtcttaactg cttcttccat atcttttact atatgtatgt cattaaatcc tttattttta
    45841 gcacaatttt ctatatttga tgcagtttct cctaataaga ccaatgattt aacatatgac
    45901 tttgcagttt caagaagttc atcaaaatta cttcccttat ccatcccccc tgctataagt
    45961 attataggtc tatcataaga ctgtatagct tttatagtgg aatctggatt agttcccttt
    46021 gaatcattta catatattac attgtctaaa tttcttacaa actcttgtct gtgttccact
    46081 cctttaaatg tcataagtac gtcctttata acttctaaat caattttgca gacatatgct
    46141 attgctatag ctgccataca attttctaag ttatgacctc caggtaaact tacatcatct
    46201 ttatttagaa atttgatttt atcatctata tctattatta tgtcattatt ttctaaatat
    46261 actcctccat ttactttttt agttcttgaa aagtaaatta ctttggcatt gcatttatca
    46321 gctaaagatt ttactatctc atcatcatag tttaatacac agaaatcctc aacagtttgg
    46381 ttcataaata tatttgcctt tgcttctatg tatttttcca tagtatggtg tctatttaaa
    46441 tggtcctctg taatatttaa tattgcgctt actttaggtc taaattcatc tatactctca
    46501 agctgaaaac tgcttagttc agttactaac acagactctt cacttgaagt ttctatagta
    46561 tctattacag gatttcctat attaccaact acatatgtat ctcgttttgc tcttgaaaaa
    46621 atttctccta ccaaactagt tgtagttgtc tttccatttg tacctgtaat ccctataaaa
    46681 attggattat tcgatagttt aaaagctaat tctacctcac caattatata cttgcctgaa
    46741 ttttttaatt tcaatatgaa tggtaggtct agtggtacac ctggagacac tacaaccata
    46801 tctatatcat ctacatcttc tgggtgatgt cctaatatgt attttatgtc atttatagat
    46861 ttcaattcat caagtatatt tctcaattta ttttcatctt ttatgtcatt tacgattata
    46921 cttgcaccca atttatctaa atgtttaatt gtagatatac cagtttttgc aagtcctact
    46981 aataaaactt tttttccttt taagtccatt tttcattccc cctagcccta aaatactgct
    47041 attatactta tccaagctaa aacaactgtt ataatccaaa aaataaatac aactcttgtt
    47101 tctggccaac cacactgttc aaagtggtgg tgtattggag ccatcttaaa gaatctcttt
    47161 cttgttgcct taaaatatcc aacttgaatc aaaactgata gagcctccgc aaaataaatt
    47221 cctccaatta taggtattat aagcactgag ttagttagaa ctgaaaatgc tacaactgca
    47281 cctcctaatg ccattgaacc tgtgtcgccc ataaacactc tagccggata tgaattaaat
    47341 cctaagaaac ctaaacatgc tccaacagtt gctgctgcta aaactgcgac ttctgtattt
    47401 ccagcaatag aacttgcaaa tagcataaag aatacagaaa ctattaatgt tactcctgat
    47461 gctaatccat ctaatccatc agtcaagttt acagcattta ctattgctac gattataaac
    47521 atcattattg gtatatataa tattccaaca tttatcacaa aatctgtaaa tggtatcata
    47581 agttgtgaag cacttgatga tgatgtatac tgataaaaag caacataaaa agataatgca
    47641 acttgaagga ttattttttg atatgctttt agtccaagtg atctttttag ctttattttt
    47701 ataaaatcat ctaaaaagcc aataaaacca aaacctgcaa tacatataag acctactgcc
    47761 atatcatgac taacttttac tcttgtaagt ccagttatta gaattgcaac aatcattata
    47821 attccaccca tagtaggtgt tccgttttta gctagatgtg tttggggtcc atcatctcta
    47881 actgtctgac caaatttaaa ttttctaagc attggtataa atattggtcc tattataatt
    47941 actattaaaa acgcaatcaa tgcggtgtac gtaagctctg ttattcctaa catcataaaa
    48001 ctcctctccc ttgtcaatta actcattagt ttaagcttat ttatttagat attcgactat
    48061 tttttctaat ctcatgcctc ttgagccttt tactaaaata gtgtctcctg tttttactaa
    48121 ttcatttaac ttgttaaaca catcttctct attctcaaag tgatatatat tggctgaatt
    48181 gaatcctaat tgttttgctt cttctccaat aaacactgaa ttttcaccta tagttattat
    48241 aatatcagta ttattcatag atgattttcc aactaatcta tgaccatact ctgaaatttc
    48301 acccatttct agtatatctc caagtatcgc tacccttcta cctttatatc ttccaagtat
    48361 ctttaaagca gcatccatag aatctggact agcattatat gaatcattaa ttattgttaa
    48421 tttttcattt tttattatgt ctagtctcat ttttgtccct ttaaaatttt ttaaaccttt
    48481 ttttatataa tctaaagaaa tatttagaca caaaccaact aatatagcag acattgcatt
    48541 atatatatta tgttctccta ttgttggtat aaatatttcc tcttttttcc catttattac
    48601 acatataaat gttaaactat cctcttccat agtataactt tcacaataaa catcattgtt
    48661 tttattaaag ccaaatgttt ttaacttata tacatgttct ttttctttta atgtagataa
    48721 aaacttatca tctccattta caattaaagt atttgtttca tcaaagtttg aagtaatctc
    48781 catctttgct ttcaaaatac cctcttgtga acctagtttt tctacatgtg ataatcctat
    48841 attcgatatg actgcaattt taggatttac tatatccact aaatatttta tttcattgaa
    48901 tccagacata cccatctcta ttacagcaca ctcatgttct ttatttagat taaataaagt
    48961 caatggaact ccaaaatgat tatttaagtt tttttcattt tttagtatat ttaactttgc
    49021 agatatggca gagtaaatca tatctctagt agtagttttt cccacactac ctgtaacacc
    49081 tataaatgga atatcaaatt tttctttata gtattttgaa atatctccta gagccaaaga
    49141 tgtatctttt acctctatta aatttatatc cgaactttct aattttattc cattactttc
    49201 attttttata aaagttttac atccactatc atatgcagac ttcataaatg tatgcccatc
    49261 taaattttct ccaactatgg ctacaaatgc attttgggca tttgcctccc tgctatctat
    49321 aactatatca cttacacagt cattataatc tccatatatt aacttcccat tagttgcaag
    49381 tactaactct tttattgtta agcactccat tattaaactc ctcctttaaa accttagcta
    49441 tattctctta gcaacaaaag gcaatgtata ccgttatata tacattgcct acgataactc
    49501 ttaactttat aattatatac tatatttctg tttttttgaa gatgtttatg ggtatatgtt
    49561 aattatctgt tactttttag ttttcaaaat atagggttat acttgagtct tcattaactt
    49621 ttactccagg ttttgggaat atatccttta cctttgtatc ttctggaagt tctatatctg
    49681 catctaagtc tggttttaac ttcgcatcct ccaatgcctt tacagcatct cctattttta
    49741 gatttcttac atctggcact ttaacttgct tcttttcata ctcagctttc tcttcttctt
    49801 tatatactgg tttaactccc aaatatttta aagagtcatt cattatttct ttcactattg
    49861 gtcctgctgt agtactacca aatgcactta ctcctgttgg ttcgtcaaca atagcaagaa
    49921 ctactatttg cgggtcatca caaggtgcta ttccaacaaa tgaacatata tattttcctg
    49981 gagcatactt accatctata actttttgag ctgtacctgt tttaccacca agtctataac
    50041 ctggtatata tgctatcttt cctccacctt cagttacaac tgattctgca atttctaaca
    50101 tttttttaga tgtttcttta gatataacac ttcttacttt ttttggtttt actgtttcag
    50161 ttatatttcc tttattgtca gtataagatt ttaccactct tggttgcatt aaatctccac
    50221 cattagctat tgatgatata gctgttataa gttgtattgg agttactgat atagattgac
    50281 caaatgatat tgtagccaat tcaactggtc ctacattttt ttcgttatac agtattccct
    50341 tagcttctcc tggtaaatct atacctgtct tatccataag accaaatgct tctatataat
    50401 catacatttt tccaacacct aatctgcttc ctaactcaac aaatactggg ttgcaagagt
    50461 tttgtactgc ttgtttaaat tcttgtgttc catgaggtct gtaatgtctc caacatttaa
    50521 tctttcttcc tccaacagtt acactacctg tacatgtgaa tttttctcca tctttaatta
    50581 ctccttcttc aagagcacta gaagatgtaa taagcttaaa tgtagaacct ggttcatatg
    50641 tatcacttac tgctggattt ctccacattt gataatagcc ttttatttta tctttatcat
    50701 tatatttttc aagttcttct tgataatatg gatatattgg cgttcttgag tcattagggt
    50761 cataatctgg ttttgatgct aaagcaagta tatcacctgt tttagggttc atagctattg
    50821 cagtaacctt ttttgcatta tttaactcat aagctttctg tactgctttt tcagtatagt
    50881 gttgaattac ttcatctata gacaacacaa gaccattacc ttgtacaggc tcataatatt
    50941 tttccattcc ttgtggtatt tctcttcctg aagcatcagt acttactata agttttccag
    51001 gctttccttt taacttttta tcatattgca tttccacacc agatatacct gttgcatctg
    51061 aagaagtatg tcctaacaca tatggtgcaa aattcccata tgggtaatat ctttgattat
    51121 cttctgctac ccatattcca cttaatttag catctcttat ttgacttgcc ttatcatcat
    51181 ctatccatct ttttactttt acaagagcca tatttttttt gcttattaaa gcgtaaatat
    51241 ctttataatc ttcatccaaa atctcagcta ccttttcggc tgcttctttt ttatcttcta
    51301 cttccacagg tttacaccaa acagtatact tagttacact tactgctaac tctttcatat
    51361 ttctatcata tatagttcct cttttgggtt ctattggtat atctcttgtt tgttgttcta
    51421 gtgcttttgt actcaaccaa tttcccttca taagttgtag atacccagtc ctaataacaa
    51481 ggcaaaaaaa caatgcacat gctagaataa gaacgagtac cagccttttc ttacttatcc
    51541 tctttacttt tctcaaatct attcccccta gttatccaca tctatatact ttatttgtcc
    51601 atcttttgga tagtccatat tgagcaattc cttagccttt agctcaattt cttttatcga
    51661 tgttttttca gtttcttttg cctttagttc ctctaatact atctcttttt ttcttaaatc
    51721 tttttgtaaa taatagatat catacttcat ttccgagatt tttgaataac cacatagatt
    51781 caatattatt actgaaaaag ttgcaatcag taaaatgcat ttagctccta tttttttctt
    51841 atttctcttt ttataattat tctttttttt atttttatat tcatttagat tatgtatttt
    51901 ataatttttt ttcaaattct caccccgata gtatatagtt taaattttcc tctatactat
    51961 atttgttatt aatcatattt cttcctctaa aatttcatcg ctaaattaat acactattac
    52021 acaatctaat tgtatttttt tctatacaca acaaaaacct ataaattcac ttatactttt
    52081 atatgaatct ataggttaga tattaatttc tatttatttt tatcacttct agtattttta
    52141 gataatttct tccataaata taatatgtaa ctaactatct actctctgat tcctaagttc
    52201 tccattatat tacttaatac catctatatc tatattttta tatctaaatt ttcattatat
    52261 atctcaataa caaagaacat ttcttatagt gttaattgtt ttttaattgc tttaccagtg
    52321 caacaaaata tataatactt tttaattaat tataataatc ttatatataa gattattctt
    52381 tagccttata actacttata ttttttctgc tactcttagc ttagcacttc ttgaacgtgg
    52441 atttacttct atttcttcct cactaggtaa tataggtttt ctagttatta ttttcacctc
    52501 agattcttta tcacattggc atataggtaa atgttgtgga catatacaat ctgatgctaa
    52561 atgcttaaat gcatttttca ctattctatc ttctaatgaa tggaatgtta ttatacatat
    52621 tcttccacct tcattcatta tagaagaagc atcatttatc atctttgtaa ttactccaag
    52681 ttcattattt acttctattc gtattgcctg aaaagttctt ttagctgggt gaggtccatc
    52741 tattctagct ttcttaggga tagctttttt aattacatct actaattctc ctgtagtttc
    52801 tattggtttg tttgctcttt cttcaactat aaatttagct atacgcttag cccagttatc
    52861 ttctccataa tcttttatta tcttagttaa ttcatcttct gtataagtat ttacaacatc
    52921 atatgcagaa aactcacacc taacatccat tctcatatca agtggtgcat cttgcatata
    52981 agaaaatcct ctatcagctt catcaagttg atgagatgaa actcctaaat cagctaatac
    53041 accatcaatt ttgtaaactc ctattttttc taattcctct tttatatttt caaaattact
    53101 gtgaacaaac ttcactctac tttcatattc actcaatctc tcttttgctg tgcttatagc
    53161 atttttatct tggtcaaacc ctataaataa tcccttatct gacagttttt ttactatttc
    53221 tttagaatgt cctgctcctc ccatagtaca gtcaacatac acgccatctg gctttatatt
    53281 taaattctct atacactcat ttaaaagaat tgatacatga tgaaattcca tagttacctc
    53341 ccttaaattc actttttaaa ctattcttca ctaatattat ttttattttt ctttgataaa
    53401 taaacatgtg caattatgcc accaataact ccaattagac ttataacttg cgccattcta
    53461 agtggtccta acattaaact atctgttctt aatccctcta taaaaaatct tcctattgaa
    53521 tataaagtta tataagtaac tataacttga ccttcatatt ttttattttt tctaaatagt
    53581 aataaaacta taaatattcc aaaatcccat atagactcat ataaaaaagt tggatgtacc
    53641 tttactccat caaccattat tccccaaggt aaattggtag cacctccatg tgcttctcca
    53701 ttaataaaat ttccccatct tccaatagct tgtgctaaag gcattccaag tataactgta
    53761 tcagccattt ttaagaagtt aatattttta atcttagtgt atatataacc agctaatatt
    53821 ccaccaatta accctccatg tatagcaagt ccaccacctc taaaattaaa aatttgagac
    53881 atattttgag catagtaact ccaattaaat acaacataat agattcttgc acagattagt
    53941 ccaactggaa ttgctattat agctatattt aatacatcat cttctttaat tcccactctt
    54001 tttgcttctt ttattgctat taaagttcct aaaatcattc cacatgccat aagtattcca
    54061 taccacatga tgtctatgcc aaacagtgta aatgctactc tatccataac gtcacctctt
    54121 tgtattaatt gaaaatattt ccaaagcaat atgctataat tacaattaat tgtaattata
    54181 ctaaattatg ataacacatt aatgttaatt ctacaaaaaa tattaaaatt tattctacaa
    54241 ctccctacac tatattatat ctaattacta taaaattttt taaactgaat ctctcatgac
    54301 taaagttaca agtgtacata gatatttttt aatcaaaaag attgatgcat atatacatca
    54361 acctcttcta attcttatct atagctctta aatttttacc tcaatttata taaatatatt
    54421 ttataaattt gttttaccaa aataaacatt taaaaacata aactaatact taattagtta
    54481 ttcttattat gattaagttt ctatttaggc tctacaatag aaataacaca atactcttct
    54541 ttaaaatgct cttttaatct ttcttcaact tcctcaaaag taatatcttt aataatatct
    54601 aaataatcca atagatttat atccttaaaa acataagata taaaactatt acctataaag
    54661 tttatagaat caaagcactt aataaatgac cctatttttt tctttttagt tctctcaaac
    54721 tcttcttttg ataatccttc tttttttgat ttttctatat aatcaagaat tatttctttt
    54781 acttttttag gctctttaga atctccagct attatgctaa aagcataatc cacttgagac
    54841 gaaaatccag ctccaaaatt ttcatttatt aaaccttgca tatacaaatc ttcataaagc
    54901 ttacttcctt ttttaaataa catccctaca agtatatcag ttacaatctc tttacgtaaa
    54961 agttctttcc cttttaaacc aacattacta tctttaaaac ctatgttgaa cataggcata
    55021 gatataggga atttttctat aacctctttt tcttttacac cttctggttc ttctggataa
    55081 aatctttcta tactcttaga gagtttgtct actttgtaat tgtttgactt tttagttaca
    55141 tctataactt tttctacatc taagtcacca acaacaaata aagccatatt tcctggatta
    55201 tagaaagtat tataacattt atatagctct tccttagtta tcttatatat actatcaaca
    55261 gtacctgcta tatcaattct agcaggataa tttacataca ttgccttcaa gcaattaaag
    55321 tatacattcc aatcagggtc atcattgtac atttttatct cttgtgctat tatacctttt
    55381 tccttttcaa cattttcatc tgtaaaataa ggtgtttgaa catagtcaat tagatgttct
    55441 aaactctcat aaaaattttc agtagcagaa aataagtagg ctgtcattgt aaaattagta
    55501 aatgcatttg catttactcc taattttgaa aatttatcaa atgcatctcc tccatcaggt
    55561 tgctcaaaca tcttatgctc tagaaaatgt gcaatacctt cattcactct aattttctta
    55621 tcttctccaa ttggtacaaa ttctaagtca tttgaaccat aattagtagc caaaatagca
    55681 tactttttca taaaacccct tttaggcata aaatatacat ctaatccatt ttgcaatttc
    55741 tcataataaa cttcttcttt caatatatca ttaactattt tttccataga catctcctcc
    55801 attaatttct caagaagtat acagtatcaa gctctatatt ttttatagct tcaactatat
    55861 ctttttttgt aaccttttct atactagata ttatatcttg tacttcagaa tttgtctttg
    55921 ccatagattg agagaaaaca aaatcagaca taccacctat attatcagtt atagatttca
    55981 tagaattaac taaagcaagt ttactgtttt ctaattcttc atcagatata tcacctgctt
    56041 ttacactttc tacttgtttt tttatcaatt ctacagcttt atcataatct ttagtttcta
    56101 taccagatga tataaacatg atacttttat acttctctat tgaagagaat atatagtaac
    56161 ataaactttc tttttctctt acattaacaa ataatttaga gtgtggacca ccacctaaga
    56221 cattgctccc aactactaaa gcataatatt tatctatgtc tgcataatcc acatttgctc
    56281 tataacccat aactaactta ccttgagtta tttccatttg ttcatctata acttttacct
    56341 catccacatt ttttataaaa tctgctcttg gtatatttat aatttcttct ctttcaaatt
    56401 ttagattttt acttattata tctacaactt tatcttcatc aaaattacct tctacaacta
    56461 tatctatagg tgatgtttta agtatgtttt tataatgttc atataactct cttgaagtta
    56521 tactatctat ttcatcttca taaccaaatt cacttacact atatctctct cctttacaca
    56581 tagcctcaat acatttatct tgcgcatatt cctttttatc atttattatt gattgtatct
    56641 tttctcttaa attctctttt tcaatattta aatattcttc tttaaaccca ccatctacaa
    56701 caagcgtatt atttattact tcattaaaaa attctactac ttcttcaaat atactctcat
    56761 ctaaatactt ttcacttatg ttaattactt taaaactcaa tacttgacgt tctccacgtt
    56821 ttacagcatc agctcccata gatgaaccat ataaatcatc taatttattg gatattgctc
    56881 tagcactagg atatttagcg cttccacttg ctattattga tggtattaga gcattttttg
    56941 tagtttcttt ttcatccaat agtctctgaa catataaact tataagattc gatttaaact
    57001 tttctgtttt tatcaaagta agattaatat tattacctaa atttattatt tttttagtat
    57061 taaccatatg tacctcctat ttttatttaa acatcaattt taaaattgaa atttatttat
    57121 tttttaatta catatactca catataaaaa ccttctattt aattatatcc tttttattat
    57181 tttctaaaag caatattttt atttaaatta aatacaaata ttatttaaat caatatgctt
    57241 taaagtctag tttacaagct tgatatatat gatgtataat caatatgtat gtctataatt
    57301 aaaacaattt tgcaatccta tagattgatt gtttaaagtt atataaagaa tataaaaaag
    57361 aataagagag aggacgatta atatgaaatt aggtatagtt ggtttaccaa atgtaggtaa
    57421 aagcacacta tttaacgcaa taactcaagc aggtgcagaa tctgcaaatt accctttttg
    57481 tacaatagac ccaaatgtgg gagttgtatc tgttccagat gaaagattaa acaaactaca
    57541 agaattatat aattctgaaa aaatagttcc tactgctata gaattttgtg atatagcagg
    57601 tttagttaga ggagcttcta aaggagaagg tttaggaaat aaattcttat cacatataag
    57661 agaagttgat gcaatagttc atgttgttag atgttttgag gatgaaaatg ttgtacatgt
    57721 agatggttct gtagacccac ttcgtgatat agaaactata aacttagaat taattttctc
    57781 agatatagag attcttgaaa gaagaattaa taaaactcaa aaagctgcta aggctgataa
    57841 aactttaggt tctgaacttg atttattaaa atcaataatg tctactttag aagaaagtaa
    57901 gtgtgtaaga actatggaat ttacagaaga tgaacaaaca ttcgtaaatt cattggattt
    57961 acttacatct aagcctgtaa tatatgcttc aaatgtatca gaagatgatt tagctgataa
    58021 tggagaaaat aataaatatg ttcaacaagt taaagcattt gcagaaacag aagatgccga
    58081 agttgttgta gtatgtgcac aaatagaagc agaaatttct gaacttgatt ctgctgaaga
    58141 aaagaaagag tttttagaaa cattaggtct tgaacaatca gggcttgata agcttataaa
    58201 atcttcttat gctttacttg gtttaatttc attcttaact gctggtccaa aagaagttag
    58261 agcatggact ataaaagttg gaagtaaagc tcctcaggca ggaggaaaaa tacattctga
    58321 tatagaaaga ggatttatca gagcagaaac aatagccttt aatgatttgg ttgagcatgg
    58381 tactatggct gctgctaaag aaaaaggatt ggttaaatta gaaggtaaag aatacatagt
    58441 taaagatgga gatgtaatat tatttagatt taatgtttaa aatgattaat cgtatacact
    58501 ttgactatta tatataataa ctaaaaaact aagattataa taatacaata ttatcttata
    58561 ataattatat agaatttaaa aataaaagaa gagtatttca aatgatttgt ataaattatt
    58621 atgaaaaact ctttttttgg tataataaaa ttacttacat atataacatt taaatttata
    58681 aattatcttt ttatttttta aaatatgtat aacacaccta tagaaattac tattattact
    58741 atctaaagta ttttgctata atcccatata ctcttacctc aaaaacattc aaatgtaaaa
    58801 aatactacat attaataaac tttgcccaat aattcctaaa ataatatcct aacaatgatt
    58861 tatgttttta taatagtata tttttacata aaaaagtgaa cattgattaa caaagttcac
    58921 ttttttataa atttttatgt tataattcac aattttattt aatttgtttc ttttctattt
    58981 aaactatatc tatctaatat taatttttca tattcttcta ttggcattgg tctagcaaat
    59041 aaaaatcctt gagccatatc acaacctata aaccttaaaa actctgcttg ctctacagtt
    59101 tcaacacctt ctgaaacaac ttttatatca agttgctttg ccatttgaac aatacttgaa
    59161 actacaattt gactcttttt tgcatttccc actgttataa agaattgcct atctaatttc
    59221 aatacatcaa ttggcatatc tttaagcata tttaaagaag aataaccaga accaaaatca
    59281 tccatagaaa ttttaaatcc aacagatttc aaagtttgca ttattttaaa taatattttt
    59341 gtattgtcaa atattgcact ttctgtcaat tcaatctcaa ttaaatttgg ttcaatttca
    59401 tattcttttg ttattctttc aagctcagaa ataaagcctg gattctcaag atgtactctt
    59461 gataagttta ttgatatagg aaatgtgggg aaattttcat tttcccaacg tttaaaattt
    59521 ttacaaactt gggtaaatac aaacatatcc aattctgtta taaagccatt tttctcaaaa
    59581 ataggaataa atacacctgg acttattaga ccttttttag gatgttgcca acgtacaagt
    59641 gcttcagcac ctacaatttt agtagttgat aaatcaacct taggctgtaa ataaacttta
    59701 aattgttcat tttttaaagc atcatgcatt tcttgttcaa tatcacgttc ttctatgaga
    59761 gtttctttta aattttcagc ataaatctca taaactttta aatattttct ttttactgta
    59821 gtttttgcaa tcatagcttt gtcaagacag gtagaaatat ttgtttctcc ctcttcaaca
    59881 aaatatacac ctatggatgg aattaaattg agttctactc ccaaacttgt ttttatcatt
    59941 gacaattttt tacgtataag ttcacatatt tctataattg actctctatt atttttcttt
    60001 tcaaatatta tagcaaaatt gtcatttgaa attcttgaaa atacagattg ctctttaaat
    60061 atattcttaa ttatctctgc tatttccttt aatactctat ctccttcttc atacccaaac
    60121 ctatcattta ctagcttaaa cttatctata tcaaaataaa ttaaaactag attctttttc
    60181 tcatgagagg ataaaaattt tcccccttca agattaaatt tatttgaatt gccaatacct
    60241 gtaacgttat ctttaaaagc aaattcttcc aatttttcct tactcttttt atgtataaat
    60301 agtatataaa ttgttaatgc cgtaaagatt ataatcaaga ctacacatgc tgataatgta
    60361 agttttataa tagcatatga tttctcagat atagcagttt taggaacttc agaaaaaaga
    60421 taccaatcat tgattcctat tggggcataa cttaaataat atccttttcc aaacatacta
    60481 taacttaatg aacctgattt aaagtttttt atatttgact tcatattatt gatactagat
    60541 tttgatattg aatcacttct accaatgtaa gaaaataaat tttctttagt agagttggcg
    60601 tttttactgc ttggatttaa aacaatatca ccattacttc tagttatata agaatatcct
    60661 tttccattaa atgtaggtac agaaagtatt ttttcataca acttcgtact atgtgtggca
    60721 aatataactc ctttaacctc attatcttta taaattggta cagaatatac attaatatta
    60781 ctattggtat ttttatcatc ttctattaca tcttttaatt tgcctgttat aaccacttct
    60841 ccttgcattg attttaagaa ataatctctt ttagagaagt cttctatata accatctgta
    60901 gtgtatgctg taccatttgg taaaataact cccattcttt taaatgaact attaatagct
    60961 tgtcttttta gtatagaaag gatattatct acttcaaaag actcttctcc ttcaataaat
    61021 attgaaattg actctagtaa ctttatatct ccattaattt gtttttttaa cacattgacg
    61081 ctttgatttg ctatttctga aagatattga ttcgtttctt cacctaatgt cttattcaac
    61141 cttgaaccat aaatcaaaca ggaaattgta attactaaga tacttatgac agcaattatg
    61201 aacaaaccat acctattatt ttttgcatca cttaacatta tgcttcctgc ctttctcgaa
    61261 tctatgtatg tataatcatt atcttatgac aattattgta aacattttat aataatactt
    61321 atttttccat atttactgta attatacaaa attataaact ttattacaac aataaattaa
    61381 ttaatataga tattagtgtt tatattatta cattatctat tttacaatta tttacatata
    61441 aaaaaatgta atatcaaagt gaagcttgat attacatttt tgttcttgta ttttgtttaa
    61501 tttttatgct acatcttact taaacactca tttgcaactt ctttatcatc aaaatgatgc
    61561 ttaactttac ctataatttg ataagtttca tgccccttac ctgttataat tacaacatca
    61621 tccttttttg ccatacttat agcttctgct atagcttgtt ctctatcaac aacaacatgg
    61681 taattttctt ttttcttgtc aattccttca agtatatctt ttattattgc ctctggttct
    61741 tcagttcttg gattatcaga agttataata cataaatcag aatatttttg tccaattgct
    61801 cccatcaaag gtctcttttc agtatctcta tctccaccac acccaaacac agaaattatt
    61861 tttccttctg caaattgttg agttgtcttt agtacatttt caagtgcgtc aggagtatga
    61921 gcatagtcta caattacgct tataccttta tcatttggaa ctgtttcaaa ccttcctgat
    61981 actccattag aaagtctaag gccttcttta tatattggtt taggtatgcc aagtacatag
    62041 caagcagcta taactgctaa agtattatat actgtaaaca tccctggaac tggtataaat
    62101 attacttctt catatgaagg tgttattaat ctataagata ctccatccga atctgatttt
    62161 atatctctag ccataaaatc agccttagta tcaacaccat aagtgtaaca aggtacattt
    62221 atacctttta tattttcata tatctttttt ccaccttcat catctatgtt tattatattt
    62281 gccatagtag tcttaaaaaa taatttttct tttgcttttc tataatcctc taaatcttta
    62341 tgaaaatcta aatggtctgg tgttaaattt gtaaatatgc ctagtttaaa gtctgtttca
    62401 tcaactctat ttaatgccaa tgaatgtgat gaaacttcca ttgcacagta gtcacatcca
    62461 ttatccaaca tattattaaa atgatattgt aaatctatac tttctggagt tgttgaattg
    62521 gaaacaatgt ctttttctcc atcaaaaatt tttatagttc ctataagtcc aactttattc
    62581 ttatttaaag ttaatatctc atttagtata gtagttatac tagtttttcc attagtacct
    62641 gtaactccta taacgttaaa tttttgagat ggatgattgt aaaaattatc agctactttt
    62701 gccatatctt ttcttgtatc ttttaccttt ataaatgtac atccttttat tgctacatct
    62761 tcttcaacaa gaaatgcact tgctcccttt tctatggcat cttttatata cttatgacca
    62821 tctaacacaa atccttttat acatataaat aatgtacctt ttgtaacctt tcttgaatca
    62881 tattgtacat tattaatatc tatatttaat tcacccttga cattgattat atccaacccc
    62941 tgtataatat catttaattt cataaatgct ttcctccctt taaactcttt ctgctaaaat
    63001 tacactacat ataatattat attaagaatt ttttactatg tgaatggtta aaaatgcttg
    63061 aaacattgca aaaaatgctc tataattttc tataatataa ctgaggaaag gtcttctata
    63121 aaaactatgg ataataaaat cgggtactta aacgataact ttaaaatatt taatattaga
    63181 gataaaaaag atatacaatt tgaataccat aatcatgatt ttaataagat aattatattt
    63241 ataaatggaa atgtaactta ttttgttgat ggtattccct ataaactaaa gccttgggat
    63301 atactcttta tcagcaataa tgaaatacat aaaccagtta tagattcaaa tgtcttttat
    63361 gagagaattg caatatggat tagcccagaa tttatgaaaa aaaatagtga tgctactagt
    63421 gacttagaaa aatgttttaa aatagctaca gagaataaat gcaatagatt gcgtttaaat
    63481 atacatgata ttgaatctat taagagtttt attgagcaaa taaatatttc cgaatccaat
    63541 actgaatttg gaaatgaaat attgagaaat gcattattta tacaacttat gatattctta
    63601 aacagaattt tcctaaaaaa tgaaaatatg gaatcaacag aagacgtttt ttatgatgaa
    63661 actattaaga aagtattaaa ctatataaat tcaaatatag atgataagct ttcaatagat
    63721 agcatatcgt ctgaattttt tataagtaag tattatctta tgagaaaatt taaatctcat
    63781 actggaacgt ctatacacaa ttatatagtt caaaaaagat taattttggc aaagtcacta
    63841 ataaccaatg gtcaccttat gagtgaagtt tgtaataaat gtggattcaa cgattattct
    63901 agttttgtaa gggcatttaa aaaaaactac ggtgtatctc ctaaaaatta tataaacaat
    63961 aaaaatcctt tagatattac tcttttagat gaatagataa tttatgtaaa ttttatttta
    64021 ataaaacttg aagtattagt gtatttatct tactaatacc tcaagttttt taatgtttta
    64081 aaatatatca aaatataatg atatatattt ctattactta aaatatatat taaataaatt
    64141 gcatgttaac tgaacctatt tatatattta ttaaatctca cataactttt agttacacta
    64201 tcatatagct atcctatttt ttcaatatca tctcttaata tacttactct attctcctct
    64261 tttgctgtgg ttactccttt tttaatgctt aatttctgat tttgttctaa attcgtaaat
    64321 actacaggac ttattgttga tagaccattt ttttcaatat attctaagtc cattttaact
    64381 aatttttctc ccgcttttac ttcatctcct acattcacaa atacttcaaa tccatttcct
    64441 tctaagttta cagtttctat ccctaaatgt ataagtattt ctactccact tttttgggat
    64501 tttattatta ttgcatgctt agttggaaat ataactccaa tagttccatc aactggtgaa
    64561 taaatcaatc catcactaga tttaattgca aatccatccc ccatcagttt acttgaaaat
    64621 acagaatctg gcacttcttc tatatctaat atctctccat ttgttaatga atcaatcttt
    64681 tctactaaag tattttccat atttgcaact tccatatttt ttttcacttt atttttatca
    64741 acatttttag taacagtact ttcaaccttt gtttttccct ctattatatc ttttatatca
    64801 gactttattg aatctgattt tggtccaaat atagcttgaa cattgttgcc aataaccata
    64861 acacctgctg ctccaagtga tttcaatttt tctttatcta ctttatttat atcatttaca
    64921 accaatctaa gtcttgttat acacgcatct agactcttta agttgtcttt atttcctaaa
    64981 gcaatcaaaa tctctgatgc taattcattc ttagacattt caatgacttc agcgttagtt
    65041 tctgactcat cttctcttcc tggtgtcttt aaattaaatt ttcttatcat aaatctaaat
    65101 acactatagt ataatactgc aaaaccaata cctaccaaga tagccaagta ccatggagtt
    65161 ctattaggaa gaacaccaaa taataagaaa tctattaatc ctcctgaaaa tgtgaatcca
    65221 attttaactc ctaataattg cataattgcg tatgataaac ctgaaaataa acaatgtatt
    65281 gcaaataata ctggtgcaac aaataaaaac gcaaactcta ttggctcggt tattcctgtt
    65341 aaaaaagagg ttaatgctgc tgatgccatt atacctgcta caaatttttt cttttctggc
    65401 tttgcttcat gcaccatagc aagagctgct gctggaagac caaacatcat aaatggaaat
    65461 gcacctgtca taaaagtacc tgctgtgaaa tttactccat ctttaagttg agcaaagaat
    65521 atcttttggt cacccattac aagctcacca gctttattta catattctcc aaattgatac
    65581 caaaatggat tatggaaaac atgatgcaaa ccaaatggta ttaatagtct ttccaaagaa
    65641 ccttccataa atgctgctag tgtttgattt gcttctataa cattttttga gaaactaagt
    65701 aatccctctt gtattgtagg ccaaataaaa gacaatataa ttcctattgc tatagcaact
    65761 aatgaagtaa cgattggtac aaatctttta cctgcaaaaa aacctagata ctgaggtaat
    65821 tcaattttat aaaacttttt ataaagataa gcagccacta tccctataat aataccacca
    65881 aatacccctg tttgaattgt tggtattcca acaatatttg catacataga attgtctacc
    65941 atatcttctg taacacccgc cataacaccc atagatgtat tgagaattaa aaaacctact
    66001 atggctgcca atgctgcaac accttctcct tcagttaaac caacagctac cccaactgca
    66061 aatataagtg gtaagttatt aaatataatt tgacctgaac tttccattat acttattata
    66121 agttgaaatg taggattcgc caaaactgga aaatgagcca acaatgcgtc tcctgctaaa
    66181 gcattactca cgccaagtaa tatacctgct gcaggaagta atgcaactgg tagcattaga
    66241 gattttccta ctttttgtaa aacaccaaat acttttttca tttacttttc tctccttatt
    66301 attttatatt tttttaaata aaaaagactt aagtttataa aaagttacat tagtatactt
    66361 aattctaaaa ttaaacttat gttaatataa ataaacctat attaacctaa tttcagaatt
    66421 aaaaataaac tattataatt tttttataaa cataagtctt gcctgcatta tcagt
//
LOCUS       DAEPUT010000008        64294 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.008, whole genome shotgun sequence.
ACCESSION   DAEPUT010000008 DAEPUT010000000
VERSION     DAEPUT010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 64294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64294
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.008"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            213..872
                     /gene="cprR"
                     /locus_tag="KRL22_000658"
     CDS             213..872
                     /gene="cprR"
                     /locus_tag="KRL22_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HBH1271179.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTIREHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            1083..2141
                     /locus_tag="KRL22_000659"
     CDS             1083..2141
                     /locus_tag="KRL22_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH1271180.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            2392..4536
                     /locus_tag="KRL22_000660"
     CDS             2392..4536
                     /locus_tag="KRL22_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2806..2808,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HBH1271181.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            4585..5418
                     /gene="fdhD"
                     /locus_tag="KRL22_000661"
     CDS             4585..5418
                     /gene="fdhD"
                     /locus_tag="KRL22_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBH1271182.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVRKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            5429..5602
                     /locus_tag="KRL22_000662"
     CDS             5429..5602
                     /locus_tag="KRL22_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271183.1"
                     /translation="MCTKKEKQRYSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            5660..6211
                     /locus_tag="KRL22_000663"
     CDS             5660..6211
                     /locus_tag="KRL22_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1271184.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            6236..7612
                     /locus_tag="KRL22_000664"
     CDS             6236..7612
                     /locus_tag="KRL22_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH1271185.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            7612..8127
                     /locus_tag="KRL22_000665"
     CDS             7612..8127
                     /locus_tag="KRL22_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1271186.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(8205..9488)
                     /locus_tag="KRL22_000666"
     CDS             complement(8205..9488)
                     /locus_tag="KRL22_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HBH1271187.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            9676..10098
                     /locus_tag="KRL22_000667"
     CDS             9676..10098
                     /locus_tag="KRL22_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HBH1271188.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISSECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            10200..11138
                     /locus_tag="KRL22_000668"
     CDS             10200..11138
                     /locus_tag="KRL22_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBH1271189.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            11323..13347
                     /gene="ligA"
                     /locus_tag="KRL22_000669"
     CDS             11323..13347
                     /gene="ligA"
                     /locus_tag="KRL22_000669"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBH1271190.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKEMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            13507..14856
                     /gene="rph"
                     /locus_tag="KRL22_000670"
     CDS             13507..14856
                     /gene="rph"
                     /locus_tag="KRL22_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBH1271191.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNVHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            14856..15326
                     /locus_tag="KRL22_000671"
     CDS             14856..15326
                     /locus_tag="KRL22_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1271192.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            15520..16806
                     /locus_tag="KRL22_000672"
     CDS             15520..16806
                     /locus_tag="KRL22_000672"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBH1271193.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEVIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLLGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            16956..17540
                     /gene="clpP"
                     /locus_tag="KRL22_000673"
     CDS             16956..17540
                     /gene="clpP"
                     /locus_tag="KRL22_000673"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH1271194.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            17559..18809
                     /gene="clpX"
                     /locus_tag="KRL22_000674"
     CDS             17559..18809
                     /gene="clpX"
                     /locus_tag="KRL22_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBH1271195.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(18880..19407)
                     /locus_tag="KRL22_000675"
     CDS             complement(18880..19407)
                     /locus_tag="KRL22_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH1271196.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(19395..19907)
                     /locus_tag="KRL22_000676"
     CDS             complement(19395..19907)
                     /locus_tag="KRL22_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH1271197.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            20087..22450
                     /gene="lon"
                     /locus_tag="KRL22_000677"
     CDS             20087..22450
                     /gene="lon"
                     /locus_tag="KRL22_000677"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBH1271198.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLSNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            22440..23051
                     /locus_tag="KRL22_000678"
     CDS             22440..23051
                     /locus_tag="KRL22_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBH1271199.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(23317..24687)
                     /locus_tag="KRL22_000679"
     CDS             complement(23317..24687)
                     /locus_tag="KRL22_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1271200.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWISASVCFVGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(24862..24977)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25265..26344
                     /locus_tag="KRL22_000680"
     CDS             25265..26344
                     /locus_tag="KRL22_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1271201.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            26735..27415
                     /locus_tag="KRL22_000681"
     CDS             26735..27415
                     /locus_tag="KRL22_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH1271202.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            27408..28787
                     /locus_tag="KRL22_000682"
     CDS             27408..28787
                     /locus_tag="KRL22_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH1271203.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            28958..30043
                     /locus_tag="KRL22_000683"
     CDS             28958..30043
                     /locus_tag="KRL22_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH1271204.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAELFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVAITRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            30097..30456
                     /locus_tag="KRL22_000684"
     CDS             30097..30456
                     /locus_tag="KRL22_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBH1271205.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            30509..31381
                     /locus_tag="KRL22_000685"
     CDS             30509..31381
                     /locus_tag="KRL22_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HBH1271206.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            31382..31825
                     /locus_tag="KRL22_000686"
     CDS             31382..31825
                     /locus_tag="KRL22_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271207.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSKNTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            31840..32424
                     /locus_tag="KRL22_000687"
     CDS             31840..32424
                     /locus_tag="KRL22_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271208.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVELNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            32677..33714
                     /locus_tag="KRL22_000688"
     CDS             32677..33714
                     /locus_tag="KRL22_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH1271209.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            33795..34160
                     /locus_tag="KRL22_000689"
     CDS             33795..34160
                     /locus_tag="KRL22_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271210.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            34165..34482
                     /locus_tag="KRL22_000690"
     CDS             34165..34482
                     /locus_tag="KRL22_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271211.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            34530..36134
                     /locus_tag="KRL22_000691"
     CDS             34530..36134
                     /locus_tag="KRL22_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271212.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            36258..37886
                     /locus_tag="KRL22_000692"
     CDS             36258..37886
                     /locus_tag="KRL22_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH1271213.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            38151..39500
                     /locus_tag="KRL22_000693"
     CDS             38151..39500
                     /locus_tag="KRL22_000693"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBH1271214.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSAEKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            39656..40735
                     /locus_tag="KRL22_000694"
     CDS             39656..40735
                     /locus_tag="KRL22_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH1271215.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            41080..41988
                     /locus_tag="KRL22_000695"
     CDS             41080..41988
                     /locus_tag="KRL22_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH1271216.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            41993..44362
                     /locus_tag="KRL22_000696"
     CDS             41993..44362
                     /locus_tag="KRL22_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBH1271217.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            44687..45490
                     /gene="proC"
                     /locus_tag="KRL22_000697"
     CDS             44687..45490
                     /gene="proC"
                     /locus_tag="KRL22_000697"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH1271218.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            46088..48844
                     /locus_tag="KRL22_000698"
     CDS             46088..48844
                     /locus_tag="KRL22_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1271219.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            48976..49455
                     /locus_tag="KRL22_000699"
     CDS             48976..49455
                     /locus_tag="KRL22_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1271220.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            49471..49893
                     /locus_tag="KRL22_000700"
     CDS             49471..49893
                     /locus_tag="KRL22_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBH1271221.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            49933..50724
                     /locus_tag="KRL22_000701"
     CDS             49933..50724
                     /locus_tag="KRL22_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1271222.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTMMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            50717..51517
                     /locus_tag="KRL22_000702"
     CDS             50717..51517
                     /locus_tag="KRL22_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1271223.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            51565..52620
                     /locus_tag="KRL22_000703"
                     /pseudo
     CDS             51565..52620
                     /locus_tag="KRL22_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
     gene            complement(52780..54726)
                     /gene="feoB"
                     /locus_tag="KRL22_000704"
     CDS             complement(52780..54726)
                     /gene="feoB"
                     /locus_tag="KRL22_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH1271224.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILLRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(54744..54962)
                     /locus_tag="KRL22_000705"
     CDS             complement(54744..54962)
                     /locus_tag="KRL22_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1271225.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            55168..55677
                     /locus_tag="KRL22_000706"
     CDS             55168..55677
                     /locus_tag="KRL22_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBH1271226.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            55755..55916
                     /locus_tag="KRL22_000707"
     CDS             55755..55916
                     /locus_tag="KRL22_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HBH1271227.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            56067..56732
                     /locus_tag="KRL22_000708"
     CDS             56067..56732
                     /locus_tag="KRL22_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH1271228.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            56798..58582
                     /gene="pepF"
                     /locus_tag="KRL22_000709"
     CDS             56798..58582
                     /gene="pepF"
                     /locus_tag="KRL22_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH1271229.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            58834..59676
                     /locus_tag="KRL22_000710"
     CDS             58834..59676
                     /locus_tag="KRL22_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1271230.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     regulatory      59909..59992
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            60572..61249
                     /locus_tag="KRL22_000711"
     CDS             60572..61249
                     /locus_tag="KRL22_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271231.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            61321..63336
                     /locus_tag="KRL22_000712"
     CDS             61321..63336
                     /locus_tag="KRL22_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH1271232.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGQLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            63386..64066
                     /locus_tag="KRL22_000713"
     CDS             63386..64066
                     /locus_tag="KRL22_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271233.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAVGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
BASE COUNT        26046 a         6856 c        11444 g        19948 t
ORIGIN      
        1 ttaaataaat ttttatattt aagtaaatac gtgtaaaatg aatataaagt ttttgaaata
       61 taaagttttt gtatctaaaa tattttattt gtaaaatagt aattaattat tgtaagctat
      121 aatatgagag tattatggtt aatgtgaatt ttaaagatat tattaaatat ataaattaga
      181 atgctattag atggataaat ggaggagtta ttatgtctaa gatattagta gtagatgatg
      241 agttagatat gttaaagttg attgaaaatg tgttgaaaag agatggacat gaagtaaagg
      301 taattagtga tgtagaaaag gctatgaaca tggattttaa ttattttaat ctaataatat
      361 tagatgttat gatgcctaag atggatggtt ttgaagtatg taaaactata agaaataagg
      421 ttgattgtcc aatactgttt ttgacagcaa aaaatatgga aagtgatatt atgtacggtc
      481 ttggtatagg tgcagatgac tatataacca aaccttttgg tgtaggagaa ttaagggcta
      541 ggataactgc tcatttaagg agagaaagta gagaaaaaaa gaatttatta actatctcaa
      601 atgttcaatt taacttttta ggcaaagaag tttcaattga tggtaaaaaa attaatttta
      661 ctaaaagtga atatctaata tgtgaatttc tagcaaaaaa taagggacaa gtattttcaa
      721 aagaaagaat atatgagtcg gtatatggtt ttgatggaga aagtgatata agtactatca
      781 gagagcatat aaaaaatata cgaagcaaat taaaacaata tgatatttat acaatagaaa
      841 ctgtatgggg gatagggtat aaatgggtgt aataagtata agtgttgttt agtgaaaata
      901 ttatatatat ctacaaaatg tttgtaaaat attaatctat atattaaaat ttaatttata
      961 gattaatatt ttttgtaaat gacaaaattg taaggtattt tgttataaaa tattaagatt
     1021 catagtgtat actaataata tagtatttag tataaatctt gagcaaagga tggttatttc
     1081 taatggatag actaaagaat attagaaaga gtttactaca gtatacattt ttatttttgt
     1141 taataggtat aacaatttac ctagtgttta aaacattgga tattaaaatg ctatcaaatg
     1201 ttatggttat ggtagataag aagtttttat tcataggtgc tttggcaata atgtgtcata
     1261 taatgcttga aggagtagta atgaagataa ttatagaaag cactcacaaa gttaatatta
     1321 gatttattgg ttttaagcta gccattatgg gattttatta taatttaata actccttttg
     1381 cttcaggaag ccaaccagta cagatatatg tacttaaaaa atgtaaaatg ccacttagta
     1441 aggcaagtgc agttgttacc aataagtcta ttatcttcca aatagtagtt actttttatt
     1501 gtacaatact tgttttaatg aattttgcta tgttagaaaa acaaatgaaa atgattatgc
     1561 ctctagtgtt tctagggata gccattaatt catttgtctt aattatgata atattagtta
     1621 ttttaaatcc taaaaaaata aaatatttta tgagaattac tataaagcat ttatcaaaaa
     1681 ttaagttttt aaaattttta gataataaga ttgaatccat agaaagtttt atagatgatt
     1741 atagtaaagc aataaatttt tttgcaaaga ataaaaaggt attaatttca actataatag
     1801 taacttttat tcaattaagt gcttacttta gtgtttcatt ttggatatat aaagcattta
     1861 atttacaagg ttatagctat atttatatac tgacattaca agcattttta tatatggcaa
     1921 tatctccaat accaacacct gggaatgtag gagctaatga attagccttt ttcactatat
     1981 tcaaatcagt attccctcaa cctttgatgg gatatgcagt atttttatat ggtggattta
     2041 tgtactattt gattctgatt ggaagtggaa tatttactgt aattactcac tatagaatga
     2101 aaaatagaat tggcagaaat attgttttaa gtgaaaacta aataagttta aagaatatat
     2161 attgagtata ttaaaaaata tgtcataaga actagaatat tttaattaaa tggttgaaat
     2221 ataaagatta ttatgacata ttttttttga aatttaagag gaattgtgag aaaattgttg
     2281 aatttaatag atagtattgc aaaatattta tgattttgca tattataaaa acactcatta
     2341 tctttaagat aaattttact tatcagggga taaatctaag gggggaattg tatggagaaa
     2401 aaaattttaa cagtttgtcc atactgtgga gctggatgcc aattatatct agtagtaaaa
     2461 gataataaga tattaagagc tgaaccggct aatggtagaa caaatcaaga aagtttgtgt
     2521 ttaaaaggtc gttatggatg ggattttcta aatgacccta aaattctaac acctaggcta
     2581 aaaaagccaa tgataagaaa acaaggtgta ctagaagagg ttgaatggga tgaggctata
     2641 aactatacag cttcaagact aaatgaaatt aaagaaaaat atggacctga ttctattatg
     2701 ggaacaggtt ctgcaagagg acctggtaat gaagcaaact atataatgca aaaatttatg
     2761 agagctacaa taggaactaa taatgttgac cattgtgctc gtgtctgaca tgcaccatct
     2821 gtagccggtc tggcttactc attaggtagt ggtgcaatgt ctaattctat accagagata
     2881 gaaaatgcag atgttttatt tatatttgga tataatggag cagattcaca tccaatagtg
     2941 gcaaatagaa tagtaaaagc taaaaaaaat ggtgctaaat taattgttac tgaccctaga
     3001 gtaactgaat ctgcaagaat tgctgatata catctaccta taaaaggtgg aacaaacatg
     3061 gttttagtaa atgcttttgg aaatgtatta atagaagaag gtctttacaa taaagaattt
     3121 gttcaaaatc atacacaagg atttgatgag tataaagaaa ttgttaaacc atatacagct
     3181 aaatatgctg aaaagattac aggaatccca gaagagctta taagaaaagc tatgagagaa
     3241 tatgcaaaag gtaaaaaagc tatgatactt tatggaatgg gtgtctgtca atttggtcaa
     3301 gctgttgatg tagttaaggg acttgcatca attgctctac ttacaggtaa ttttggtaga
     3361 gaaagcgttg gaataggacc tgtacgtgga caaaataatg ttcaaggagc ttgtgatatg
     3421 ggagctcttc ctaatgtata tcctggctat caaaatgtaa ctgatgataa gataagagaa
     3481 aagtttgaaa aagcttgggg ggtaaaatta tctcctaata atggttatag tttaactcaa
     3541 gttccaaatt tagtactaaa agagaaaaag cttaaagctt attatatatt tggagaagac
     3601 ccagtgcaaa gtgacccaga tgcatcagaa gttagagaag cattagatga attggaattt
     3661 gtcattgttc aagatatatt tatgaataag acagcacttc acgctgatgt tatacttcca
     3721 gctacttctt ggggagaaca tgagggagta tatacatgtg cagatagagg attccaattg
     3781 atgagaaaag ctatagagcc acaaggagat gtaaaaccag actggcaaat tataagcgaa
     3841 atttctacag caatgggata tcctatgaat tataaaaata ctaaggaaat atgggacgaa
     3901 cttagacaat tatgtccaag tttcttaggt gctacttatg aaaaaataga aactcaagga
     3961 tgcgttcaat ggccttgtaa gagtgaaagt atggaagata aaggaactat gtatctgtat
     4021 gaaggtcaaa agttttctac tcctaatggt aaaggtaatt tgttcgctgc tgaatggaga
     4081 ccccctatgg aagttgaaga tgatgaatac ccatttagtt tatgtactgt aagagaagtt
     4141 ggacactatt cagtaagaac aatgactggt aattgtagaa cacttagttc attagaagat
     4201 gaaccaggac gtgttcaaat aaattctaat gatgctgaaa aattaggaat tgaagatgat
     4261 gaattagtta gaattagttc aagaagagga agtgtaataa caagagcaac agttactgat
     4321 agagttaagg aaggtgcaac atatatgact tatcagtggt gggttggagc ttgcaatgaa
     4381 cttacaatag caaatttaga ccctatatct aaaacaccag agtataaata ttgtgctgtt
     4441 aaacttgaaa aacttgaaga ccaagaatta gcagaaaaat gtgtaagaga agagtatcaa
     4501 agtttgaaag acaaaatgac agctacaaat atctaatgat ttattagatt taagatttat
     4561 aaaaggcaga aaggctaata ttttatgaac aatatatact caaaaactaa attacaagaa
     4621 aatagtaagg ataaagtttt tgaaaatagt tatagtctag tggactacaa atatttaaat
     4681 tcttttaatg tagaagtaag aaaaataaat gaacatgaag tatcaataga taatgaagaa
     4741 ataattgcag aatatccact tagttttatt ttaaatgata aatatgtaaa tacattttta
     4801 tgtaccccat ataatttaga ggaacttata gtaggattct tgaaaacaaa aggatacata
     4861 gaaaacaaaa aaagcttatt aaaatttgag ataaatgaga gtgaacgttt tgcaaaagta
     4921 actattcaag agaaacaaaa aaatcaagat gagcaaatta tatttttaaa ttcactagac
     4981 tatataacat gtgctcctgt aaagagcaat ataaaaataa attatgatac gatttacagt
     5041 ataatggata aaaatttaaa ttcatcagaa ttatttaaaa atactggtgg ggtacatagc
     5101 gtatctgtat ttaattttga taaaaaaata gtcacttgtg aagatgtagc aaggcataat
     5161 gcaatggata aggctattgg attttgtgtt ttaaatgaca taacattaaa agataaaatt
     5221 gtggctgtaa gtggaagaat atcattggaa atgatattaa aagcagctat gactcaaatt
     5281 cctattgtag tatcaaaatc agcaccgact aatttatcaa tagagctttc taaaaaatta
     5341 aatataacgc ttattggatt tgtaagagga agacggatga atatttatgc aaatccacag
     5401 agagttatta aaaagtgaga atgaatatat gtgtactaaa aaagaaaagc aaagatattc
     5461 aaagtgtgaa atctgtggag tattaattga tgatactgat aaggtgtata ataacacata
     5521 caatttgtgc aaaaaatgta aacgaaatat aagtactgag aaaatagtga aatatataaa
     5581 tatatatgat gaaagtaagt agacatatga tgaaaataac tagagggttg gaaatataca
     5641 aattgaaagg tgggataata tgaaaaataa aataggctct tttgtaatag cagacccaaa
     5701 caaatgtaca ggttgtagag cttgtgaagt agcttgtttt acaatgcata atcagcataa
     5761 taatgtgggt tatacagttg gaacagttga tatacctgtt atacctagac tttacttagt
     5821 aaaaggtgac aatttctgta tgccaataca gtgtagacat tgtgaagatg ctccttgttt
     5881 aaactcatgt ccacaaaaag ctatagttaa agaaaacaat attatgtctg taaatgaaga
     5941 aaagtgtata ggatgtaaaa cttgtctgct agcatgccct tttggagcta tagacttact
     6001 tccacaatat gaagatggta aagaagtaga acaagtaatt ttagatgaaa ataagaagat
     6061 agcttataaa tgtgacttat gtaaagacaa tgaaaaaata gcttgtataa gtgcatgtcc
     6121 tcaggaagca ttaaaacttg ttactccaat agatgacaaa aaagctaaga atagacaagc
     6181 tgcacttagt ttattgttaa caaataaata aaggatacag gggtaggtga cgtttatgat
     6241 aataaatata gataaggatt tatgtactgg atgtagagaa tgttcaaagg tctgtccagt
     6301 aaatgctatt gaaggtgaag agggaaagcc acaagagata aatttagata gatgtgttat
     6361 gtgcggtcaa tgtgttcaaa cttgtaaatc ttatgcctca gttatagatg aaggatttga
     6421 gtttttacaa gagaaaaaac aagaaagaga gataccagag tctataaatg aacctatatt
     6481 tgcagcatac aatgtatgtg atatagataa ggtgaagaaa gctttaagtg acccaaatgt
     6541 attcactatg gtccaatgtg caccagcagt tagagttgct ttaggagaag atttcggata
     6601 ttatttagga tacttaggtg ctgggaaaat ggcagcagca cttagagctt taaattttga
     6661 tagagtctac gatactaatt ttgcagcaga tttaactata atggaagaag gtagtgaatt
     6721 aattaaaaga gtgacagaag gtggaactct tccaatgttt acatcttgtt gtccagcttg
     6781 ggtaaaattc atggaaaaaa attatcctaa attaactaat catttatctt cttgtaaatc
     6841 acctcagcag atgggtggtg caatatttaa aacttatggt gcagagataa ataatgtaga
     6901 tgcatcaaag atatttagtg tttctataat gccatgtaca tgtaaaaaat atgaatgtga
     6961 tagagaagaa atggattcta gtggatatag agatgtagat gtagtattaa ctactagaga
     7021 actagcttat ttaataaaag acatgggaat tgattttaaa aatttaagag aagaaaaatt
     7081 tgatagtcct ttaggtagtt atagtggagc tggaactatc tttggtgtta ctggtggggt
     7141 tatggaagct gctataagaa caggatatga gcttataact ggagaaagta ttcctgatgt
     7201 agaagtaaaa caagtaagag gagaaaatgg ttttagaaag tcaactatta aaataggaga
     7261 cttagactta agagttggag tagtaagtgg attaaaaaat gtaataccag tgcttgaaga
     7321 cttggaaaaa ggaaaattag atgtagattt tattgaagtt atgacttgtc ctgttgggtg
     7381 tgtaagtggt ggaggtcaac caaaaatttt actagaagaa tataaggaat tggcttatga
     7441 aaatagaaca aaagcaacat acgtgcatga tgaacattta gcaattagaa aatctcatga
     7501 gaatcctgat attaaaaaac tgtatgatga atatctggta gaaccattag gagaaaaatc
     7561 tcatcatcta ttacacacta catattgtat aggaaaggaa gtggctaagt gatgaactat
     7621 tttgttatag cagaccctga taaatgcata ggatgtagaa cttgtatgat aggatgtgta
     7681 gttgcacatt cagatgaaga tattttttac caaaatccag atgaaataaa ttttaatcca
     7741 aaactttctg tcataaagac aaaagaagta agtgctccaa tacagtgtag acattgtgaa
     7801 gatgctcctt gtgcaaaggc atgtccaaat ggtggtatag ttagggttgg taacacaata
     7861 aaaataaatg aagaaaattg tataggatgt aagacttgta tgttagcatg tcctataggt
     7921 gcaatagaca tagttacatt aaaagatgta gatgaaggaa agctttgctt tagagaaaga
     7981 atgacagcaa ataagtgtga tttttgtata gaatcgccag aagggcctgc atgtgtaaat
     8041 gtttgtccaa ctaaggcatt tactatagtt aaggatgagg atatagatag taaagttaaa
     8101 aataagagaa aattagctat attgtaatat aaaaaagatg gagttttatt tatgattaaa
     8161 agctccatct tttttattat aatatttata tatctaaaaa tcaattattg cattagttta
     8221 tctaatcttt ctttattcaa ttttttcatt cctatagaag ttataataag taaagtatag
     8281 gcaattataa ctgataaaat tataatagac caagaaaatc tgtatccaaa attatcaact
     8341 aacaatccaa ataatgttga acctaatgca aatcccactg caaaaattaa ttgtacgatt
     8401 ccatatatgc taccaaactc cttttgacca aagaaagagc cagttaaata agcaggacca
     8461 atcatataag caaatacaga aagacctttc aaaatggcaa atacaaatgc aaaagtagaa
     8521 gatttatcta ccaatagtaa tgataaagtt gctataagaa ccaatacaaa agatataata
     8581 agtggctttg tttgaccgaa tttatcaaac aataatcctc caaataaatt accaatgaga
     8641 gcaaataagg caaatgtgga gcctactgtt cctattagaa taggatttag ataatttcta
     8701 agataagttg gatattgtac ggataatgat gaaacatata taccaacaaa tataaatcca
     8761 atagtcataa tccaaaaata tttaattttt ttagcttctt ttaatgtata accccatact
     8821 gaaggagaaa ttgtatcaga tgctttctct tttttacctt tagattttac cttttcatta
     8881 atatctttag gcatcctgag tatgaataat attacaggta taccaactat taatgctata
     8941 attccaaata ttagataaga acgactgtat ccttgagttg ctaataagcg aactgcaagt
     9001 ggttgtagaa atatactacc aatagaacca ccagcaaaag caaagcccaa agcttttcct
     9061 ttgctttctt catcaaacca agcacttatt aaaacaggta ttcctatagc agatataatt
     9121 gtagcgccaa tttgaacaat acatgataca gtgtaaaatt gccatagttc agtacatata
     9181 gaaaaagtag caaaagcaat actagaaatt atacaaccta ataaatatag tatcttaata
     9241 ttgactttag aaaataatac acctataaaa ggtgatgcaa ttgctgaggc aatagtacca
     9301 atagtgaata ttagagaaaa agaagctaaa ctaaagcctt ctccttctac aacataactt
     9361 ataaattgag gctgtatact tgctacaata ctaaatggaa cagcttgtat caacatacaa
     9421 ccaagtacta taacccaagc atttgaaaag tttttaatgc taaatttatt gtttagtaat
     9481 gtattcatgg tatctctcct ttaggttatg atttgtagat attaatctaa ttattctaat
     9541 tttatatatt agttttggat agcctaacta tttaaatata atttgggtat taatataaaa
     9601 attaactata aaaattgatt attttaaatg tatggggtaa attaaagtat ataaataaat
     9661 gaaaggatgg ataaaatgtc atttgaaaaa ataaataata ataacctaga taaaatacac
     9721 aacaggaagt gtattatgct tgtaaacttt aataaaaaag aattatcatt aattaaaaat
     9781 gtaagtaact ttgctggaat aagagaccat atcatcttaa gtgataaaaa tggagagaat
     9841 ataataagag acattttaga tggaaatata tcaagtgaat gtgaaaatgg gattaagagt
     9901 aagtctgtaa tatttaataa cactccaagc acacaagtaa atgcattttt agaagggcta
     9961 aaaaaagtga gaataaatag accttttaca gctatggtaa cagagacatc tattgattgg
    10021 acattgaata atttaataga aaatttagtt caagaacgta atgctatgtc tttaggaaaa
    10081 acaattgaac ataagtaaat ttaagatatc ttatagtaat tttaactaat gtacattgag
    10141 tatcatatta tattttagaa tataaaattt taaatgtggg tagatggagg agatttgaga
    10201 tgaaagtttt atttacaata aattatggaa aagaaaaatt tgataaaata agagaattag
    10261 gctatgatgt catacattac tctgaagata gtattgaaaa taatgaggat gtaaatacag
    10321 cagatgtact agttacatac aatccatttg agagattaga tatttctaag atgaaaaatt
    10381 tacaatatat acagacaact agtgtaggta tagaccaact tccaaaagaa gaggtattga
    10441 agagaaatat taagatagct aataatagag gtggatatag tgtacctatt ggtgaaagta
    10501 ttgtattgta tattttagaa atatataaaa atagtgcaaa attttttaaa caacaacaaa
    10561 ataaagaatg gaagatggat ttttctgtat cagaattgta tggacaaaga gttggatttt
    10621 taggaacagg tactatatct tcagaagcag caaaaagatt aaaagctttt ggtgtagaaa
    10681 tatggggtgt caatactgat ggaagtagta aaaaatactt tgataagtgt tttgctactg
    10741 aggatatgaa tattgtattt gaagaatgtg atatagtagt tgtagcaatg ccttctacaa
    10801 aaagtacaga tggaatagta aacaaagata tgtttaaact tatgaaagat ggttctgtat
    10861 ttataaatgt aggtagagga aatacagtta atcagaaaga tttagaagaa tgtgtagaga
    10921 aatttagagg ggtagcatta gacgtatttg aaagtgaacc tttaaacaag gacaataagt
    10981 tgtgggagtg cgaaaatgtc atagtaactc ctcataattc ttgggtgtca gataaaaaca
    11041 aagagagaac atttaatatg gtttataata atttgaaaca ctatataatg gagaataaac
    11101 ctgtagataa tgttgtagac atatcaagag gctattaaaa ataaaaaatt ttgataaaaa
    11161 taaaaactct tattagtcgt attaaagata ctaataagag tttttttgta ataaatttaa
    11221 agccaaaaaa gtgatatact aaaaaatata taaataggag ataattaatt atagggaaat
    11281 ttcaaaataa tttaatttta aaaatatgaa gaggtgcaaa aagtgagcgt aaaagatgaa
    11341 attaataaac ttatagagac aataaactac cataatgaaa ggtattataa tcaagatagc
    11401 ccagaaatat cagattatga atacgataag ttaatgaagg agttaatttc tttagaagaa
    11461 gaacatccag aactaaagag aattgattct ccaacaaata gggtaggcgg taagccatta
    11521 gataagttca atcaaattgt acataaaact cctatgttga gtttatcaaa tgctttttca
    11581 gagcaagatt tgagagattt tgataagaga gttcaagaat atgtgggaga aaatgttgaa
    11641 tatgttgttg aatttaaaat agatggtctt tctgtaggtc taacttataa caatggagag
    11701 tttgaaaaag gagcaactag aggagatgga gttgtaggag aagatatttc tcaaaactta
    11761 atgacagtaa aaagcatacc tcttaagata aatgataaaa aagaactaat agttagagga
    11821 gaagtatata tatcaaaaga taattttaga aaagtaaatg aacaacaaga agaacaagaa
    11881 cagccattat ttgctaatcc aaggaatctt gcagctggtt cattgagaca attagaccca
    11941 aaactaacag caaagagacc attagatata tttgtattta atatggaaaa tatagaagaa
    12001 tacgatttag aaagtcacag tgaatcacta gagtacttag aaaaactagg attttcagta
    12061 agtcagagtt ataaagtttg taaaagtata gatgaagtta ttgagcatat tgaatactgg
    12121 acagataaca ggggtaattt agactacgaa atagatggta tggtaataaa agtaaacaat
    12181 ataaaacaaa gagacgaaat gggatataca gccaaaagtc ctagatgggc aattgcatat
    12241 aaattcccag cagaaaagaa gaaaactaaa atagtagata taatagtaga agttgggaga
    12301 actggtacaa taacaccttc agcaattctt gaaccagtca gacttgcagg taccactgta
    12361 agtagagcta cacttcacaa tgaagattat ataagagaaa aagatataaa aataaatgat
    12421 acagtattag ttcaaaaagc aggggacata atacctcaag ttttagaagt tataaaagaa
    12481 gaacgtactg gagatgaaat agattttaaa atgccagaaa agtgtccagt ttgttcagag
    12541 ccaacaataa gattagaagg agaggctgct gtaaaatgta tcaatatgtc ttgcccagcc
    12601 caaataagaa ggggaattat acactttgtg tcaagggatg caatgaatat agatggattg
    12661 ggagaatcta taattacact gctattaaat gaaaaaatta ttcaagatgt atctgattta
    12721 tattatataa aaaaggaaga tgtagtcgac ctagagagaa tgggcgaaaa atctgctgac
    12781 aatttaataa attcaattga aaaatcaaaa gaaaatgatt tatggagact tataaatgga
    12841 ttaggtatta aatttatagg agttaaagca gctaagatac ttgcatataa ctttaaggat
    12901 ttagatgaag taatttctgc aactagtgag caactagaag aattagagga atttggaagt
    12961 ataatggcaa acagcgttgt cgagtttttt aaggaagaca aaaatatgaa cgttataaac
    13021 aagttaaaaa atgtaggagt aaatacaaaa tcattggata atacaggtga aaaagtagaa
    13081 aaaatatttg aagggatgaa aatcgtattg actggtacac ttcctacatt aaaaagaaat
    13141 gatgcaaaag aaatgataga aaaaagaggt ggaaaagcta catctagtgt tagtaaatcg
    13201 acaacatttg ttttggcagg tgaagaagct ggttctaaac ttactaaagc aaatgattta
    13261 ggaattaaag ttatagatga agagagattt ttagaattat taaagttatc atcgaaagat
    13321 gaagtaaaag ctgtattaga gagttaaaaa gtcgcttaat ttagtagaaa actactataa
    13381 ttaatgatag aatagttcag taagctaata agattacgaa aaatgacaat aattaatatt
    13441 tgacaaaatt aaaaattata aaaataaatt tataaaaaat aaaaaatatg agaaaggata
    13501 taaaaaatga ccagaagtta tgatagaagt aatgaacaga taagacctgt aaagataact
    13561 agagattata caaagtatgc agaaggttct gttcttatag aaatgggaga gacaaaggtt
    13621 atatgcactg catcagtgga agaaaaagtt cctccttttt taagaaatag tggtactgga
    13681 tggataaatg ctgaatattc tatgctacca agagcaacac aacaaagaaa gataagagat
    13741 gcatctaggg gaaaaattga tggaagaaca caagaaatac agaggttaat aggaagagca
    13801 ataaggtctg ttgtagactt gaataaatta ggagaaagaa ctatttgggt agattgtgat
    13861 gtgattcagg cagatggtgg aactagaact gcatctataa caggggcatt tgtagcagtt
    13921 gcagaagcaa tatataaatt atataaagca aagacaataa aagagatgcc aataacaaat
    13981 tttgtgtctg caattagtgt tggtattgta aatggaatac acatgctaga tttatgttat
    14041 gaagaagatt ctaaagcaca ggtagatatg aatataataa tgactgataa gtgtgagttt
    14101 gtagaagtac aggggacagg agaagagaaa cctttttcga gagcagattt aaatttattg
    14161 ttagagttag gtgaaaaagg gaataaagaa ttaataaggc ttcaaagaga agctttaggt
    14221 gaaatatcag atgagatatt gggtatggat tatggtaatg aagtagtgat tgctactaat
    14281 aatgttcata agctagaaga aataggtgaa atcttaaaag attttgaata taaagtgtac
    14341 tctttaaaag atgttgattt agcaggtata gagatagtag aagatggaaa aacatttgag
    14401 cataatgcgt tgataaaagc tagaacaata gcaaaaaaga ctaaacttat agcaatatca
    14461 gatgattctg gcttagaagt agatgcttta ggcaaaaaac ctggtgttta ttcagctaga
    14521 tatgcaggag aacatgcaac agatgaagaa aatagaaaaa aactgttaaa agctatgcaa
    14581 aatgtaccaa tgagcaaaag aaatgcaaga ttcgtctctg caatagcagt agtttttcct
    14641 gatggaaaag aatttgtagt aagaggaatt tgtgaaggaa tgataggatt tgaagaaaaa
    14701 ggtaaaaatg gttttggata tgatagctta tttatagtaa aaggatatga taagactttt
    14761 ggtgaaatac ctagtgttat aaaaaattca atcagtcata gagcaaacgc actaaaactt
    14821 atgaaacaag agtttataaa aagggtagtg aagtaatgaa aataggcata gtaagcgaca
    14881 cacatatgat gattaaaaat atggaaaaaa caataccata tttgaaagaa tgtgacctaa
    14941 taattcatgc aggagataac tttactgatt caagatatat tcatagcatg actaatgtag
    15001 gtattattgc agttaaaggt aattgtgact ttgatgctgt tgaggaagaa gttgtctttg
    15061 aagtggcaaa taaaaccata ttcttatgcc atggagataa gtatggtgta aaatatggaa
    15121 ctaatatgtt agaaaaaaag gcaactgaag ttgatgctga tatagttata tttggccata
    15181 cccatacccc atttagagaa attaaagatg gtgtacttta cataaatcct ggaagcactt
    15241 cacttccaag aggagtatcg tataaaagtt ttgtcattat ggatatagaa gaagatgaca
    15301 taaaaattga agaaatacgc atataaaggt gtatttatct aaaaaaatgg caaaaaacgc
    15361 tcaaaaaatt aaattttatc aaataagtac aacgatatta atggaacact tgtaaataaa
    15421 aaaacttatg tgatataatt aagtggttga attataaata gaatgaatta taataccgtt
    15481 atcgggtatt acataaatat cactaggagg attagaagga tgaaagcaga actaattaaa
    15541 aaagagggta ataaagttac tttaaaaata acagtagata acaataaatt tgaagcagca
    15601 gtaaataagg cttataataa aagcagaaat aaatacaata tacctggatt tagaaaaggt
    15661 aaagctccaa gaattgttat agagactcaa tacggaaaag gtatattcta caatgatgct
    15721 atagaaatat tattcccaga agtttatcca gaagttatca aggaattaga catagaccca
    15781 atagacaatc cagatttaga tatagaagaa ataagtaaag acaatgggtt ggttatggtt
    15841 cttaatgtag aagttaaacc agagtttgaa ttaggaaact acaagggtat agaaatagct
    15901 aaggttgaga atactgtaag tgacgaaaat gttgatgcta aactacaaga aatggttgaa
    15961 aaaaatgcca gattagtaag tgtagaagac aaagctttag aagatggaga tacagctata
    16021 atagacttcg aaggttttga aaatggtgta gcttttgatg gtggtaaagg tgaaaattat
    16081 aacttagtta taggttcaaa cacatttata ccaggatttg aagaacaatt attaggtaaa
    16141 aaagctggtg aagaagtaga agttaatgtt actttcccag aagaatatca ctcacaagat
    16201 ttagctggaa aaccagttgt atttaatgta aaaataaatg atgtaaaagt aaaagaatta
    16261 tctgcacttg atgatgaatt tgctaaagat actagtgaat ttgattcttt agatgaatta
    16321 aaagcagatg taagagctaa gttagaagaa gaagctaaaa atagagcaga tgcagaaact
    16381 agaaattcag tagtagaaaa agttgctgaa aatacagaaa tagaaatacc agaagttatg
    16441 atacaacatc aaatagataa tatgttaaat gaacttaact accaattaca atatcaagga
    16501 tttggattac aacaattact agagatgact ggtagaacta tggaagaatt aagagaagag
    16561 agaaaagaag atgctaaaaa attagttaag tcttctttag tattagaagc aataactaaa
    16621 gctgaaggaa ttgaagcaac agaagaagaa tttaaggctg agttagaaaa aatggcttct
    16681 gcttacaata tggaagtaga aaaaatagaa gcttctttaa gagatgctga caaagaagat
    16741 ataaaaggtc aaataaaaat aagaaaaaca atagatttat tagttgataa tgcaacaata
    16801 gcttaataaa ataaacgcta actaatatag ttgacgttat gaaatgttta gtatataatg
    16861 atgtgcaaat ataatttagt taaatgcgta taataattta cagtagctta aaaaaagcta
    16921 ctgtaaatta tatagaataa agggggtatg aaaccatggc attagtacct gtagttgttg
    16981 aacaaacagg aagaggagaa agatcttatg atattttttc tagactatta aaagacagaa
    17041 taatcttctt aggagatcaa gttaacgatg ccacagcagg gcttatagta gcacagctat
    17101 tatttttaga agctgaagac ccagacaaag atatacattt atatataaat tctccaggag
    17161 gaagtataac ttctggaatg gctatatatg atactatgca atacatcaaa ccagatgtaa
    17221 gtactatatg tataggtatg gctgcttcta tgggagcatt cttgttggca gcaggagcaa
    17281 aaggaaaaag actagcacta ccaaatagtg aaataatgat acatcaacca ttaggtggag
    17341 ctcaaggtca agcaacagat atagaaattc atgcaaagag aattttaaaa ataaaagaaa
    17401 ctttaaatga gatattatct gaaagaactg gtcagccatt agaaaaaatt aaaatggata
    17461 ctgaacgtga taacttcatg agtgcactag aagccaaaga atatggttta atagatgaag
    17521 tatttacaaa gagaccgtag atagagagag gtgttaatat gtctaaatat gaagaaaaac
    17581 gacaattaaa gtgttcattc tgcggtaaaa atcaagatca agtaagaaga ttaattgcag
    17641 gtccaaatgt atatatttgt gacgagtgtg ttgaactttg tgacgaaatt attcaagaag
    17701 agatagaaga tactatagat gaggatacta catctttacc aaaaccaaag gaaatgatgg
    17761 agattctaaa tgattatgta ataggtcaag aaaaagctaa aaaagcttta tcagttgcgg
    17821 tttataatca ttataagaga atatacagta aaaaatctag tagtaaggat atagaaattc
    17881 aaaagagtaa tatactttta ttaggaccta caggttctgg aaagacatta cttgctcaaa
    17941 ctctagcaag aactctaaat gtaccttttg caatggcaga tgctacatca ttgactgaag
    18001 ctggatatgt tggagaagac gttgaaaata tacttttaaa acttattcaa gctgctgatt
    18061 ttgatataga aaaagctgaa agaggtataa tatatataga tgagatagat aagattgcaa
    18121 gaaaatctga aaacccatct ataactagag atgttagtgg tgaaggtgtt caacaagcac
    18181 ttctaaaaat attagaaggt actgttgcaa atgttccacc acaaggagga agaaaacatc
    18241 ctcatcaaga atttttaaag atagatacta ctaatgtatt atttatatta ggtggagctt
    18301 ttgatggatt agagaagata attcaaaaac gtggtggaga taaaacacta ggttttggag
    18361 ctaaaataga aagtaaaaaa gaattagatt tagggaagct atatgaaaaa gtacttccag
    18421 aggatttgtt aaaatatggt ataataccag agtttatagg aagaatacca gttttagcta
    18481 ctttagagtt gttggatgaa gatgcattaa tgcagatatt acaggaacct aaaaatgctc
    18541 tagtaaaaca gtataaaaag ttattggagt tagatgatgt tgagctagaa tttgaagaag
    18601 gtgctcttcg tgcaatcgct aaaaaggcca tagaaagaaa tacaggagct agaggactta
    18661 gaagtatagt tgaaagcgta atgatggaaa ctatgtttga agtaccatct agagataata
    18721 taaagaaggt tatagtaaca gagaaatctg tgaacgaaga ctcagtaaat cctatcatag
    18781 tacttaagga tcaagaggaa agtgcataag atgatgaaaa ggagctttaa aagctccttt
    18841 ttttatgtta atatgctaaa tataaaatag gtatcattat tataaaaatg tgagtaatat
    18901 acctagaata ccaaagacga atacaattgc aatggaacca atttttcctt tatataaaag
    18961 ataaaatgat gctataaatg caattatccc atataagtcc caattaactt ctttggcaga
    19021 tgaaaaagct gctgataata tgaatcctag agtaattggt ctaagaactg tcaataagtt
    19081 ttctaccttt ttattatttt taaatttaga aaataacttt gatataatag ttagacctat
    19141 taatgcaaaa attgtaacac caatagttgc agctagagaa ccaaagaagc cagcagtctt
    19201 aaatcctaca aatgtagcac tatttattgc tacaggacct ggtgtagatt gtgatatagc
    19261 aagtaaatcc aaaaactctt gattagttat aaagtgatat ttagatataa attcttgctg
    19321 gataaatggt agcatggcat aaccgccacc aaaactaaat gcccctattt taaggaatat
    19381 taagaagagt agtattattt ctgacataga ctatatacac ctcctccaat tattaaataa
    19441 atagggctta tattgaatac accaacagat aaaactgcta taattaataa tagtatgtta
    19501 gttttagact ttggtagttt cttgaacatg ctcgtaaaag aatacaatat aagagctatt
    19561 acaacaggcg caactccttt aaaaaatcca tctaaaattt tagatgatga atttttaaag
    19621 tatagatacg ataagactaa gactatacaa aatgatggta aagcagagcc taaggtacat
    19681 ataagaactc ctggtatacc ataaagttta tatcctaata atacagatat attaactgcc
    19741 agtactccag gataactttg agctatggat aaataatcaa taaattcttc ctgctctaaa
    19801 agtttttgtt tgtttacaag ttcatcttgt ataagaggaa ccatagcgta tccaccacca
    19861 aatgtaaacg caccaatttt taaaaaggtt aaaaacaatt tcaacataat agaaacctcc
    19921 aaaagataaa taacatctaa gtatactaat attaatatta tatcataata aaaagataat
    19981 atagtatgat agtattctaa gaatttatca ttaatgttga aaattaactt gttcaaatat
    20041 ataatattaa aagcaaagca attagactag aaaaggagta atgttgatgg aacaaaatta
    20101 tactaaaata gatcatgaat taccattaat tcctctaaga ggattagcta tatttccata
    20161 tatgatatta aattttgata taggtagaga gatatctctt aaagctttag accaagctat
    20221 gatggatgaa gaacttatat ttttaacttc tcagaaagaa gcagaggtag atgagccagg
    20281 agaagaggat ttttatcatg tgggaacaat ctgtaaagtt aagcaaatga taaaattacc
    20341 aggagataca gttcgtgttt tggttgaagg tgtatcaagg gggagagtaa agaaaataga
    20401 acaagaagat gggtatttca gagcagtaat agaagaaata gtatttgata gtgataattt
    20461 ggatagtgaa acagaagttg aaattgaagc atttgtaaga aatgtatttg atgcctttga
    20521 agagtatata aatattggaa atagggtatc accagaaata ttaatatctt tagctgatat
    20581 agaagatgta gatagattta tagatacgat agctgcaaac atatatctaa aatcaagcca
    20641 aaaacaagaa atattagaag aatttgatat tagaaaaaga cttgaactta tttattctat
    20701 attattagag gaaatagata tattaaaaat agaaaagaaa ataactttaa gagtaaaaaa
    20761 acagatgaat aaggttcaaa aagaatatta tcttagagaa caattaaaag ctatacagaa
    20821 agaattaggt gaagaagaag atataaactc tgaagcagat gagtatagag aaaagcttaa
    20881 aaaaataaaa gcacctaaga caactaaaga gaaaatagaa aaagagatag ataaattttc
    20941 aaaaatatct tctatgtctc cagatgtatc tgtaagtaga aactatttag atactatatt
    21001 ctcattgcca tggaataaag agacaaaaga taaattagat ataactaagg caaaagatat
    21061 attagatgaa gaccattatg gattagaaaa agttaaggag agaatactag agtatctagc
    21121 tataagaact cttgctaagt cacttaaagg gcctataata tgtctagttg gtcctccagg
    21181 aacaggaaag acatctatag taaaatcaat cgccagagca ttaaatagaa aatttgtaag
    21241 aatatctttg ggtggagtta gagatgaagc agaaataaga ggtcatagaa gaacttatgt
    21301 aggttcaatt ccaggaagaa taattaatgg ggtaaaagaa gcccaaacaa aaaatcctgt
    21361 attcttattt gatgagatag ataagatggc agcagattat aaaggtgacc cagcttcagc
    21421 aatgctagaa gtattagacc cagagcaaaa taaggatttt gtggaccatt acttagaaat
    21481 accttttgat ttatcaaaaa tactatttgt tacaacagca aatagtctaa gtaatatacc
    21541 aagaccatta ttagatagaa tggaagtaat agaagtatct ggatatatag aagaagaaaa
    21601 attaaatata gcaaaaaaat acctacttcc aaaacaaatt aaagaacatg ctttaaaaga
    21661 aaactttata aaaatagatg atgaaacttt aagaagtata atcaaccatt atacaagaga
    21721 agctggtgta agaacactag aaagaactat tggtaagatt tgtagaaagg ttgccaaaaa
    21781 atacgttgaa gacccaactc ttgaagaggt tgttataaat aagtctgacc tagagacata
    21841 tcttggaaaa gacatgttta agtatcaact tgcagaagtt aaccctcaaa taggattagt
    21901 aaatggtctt gcgtggacag aagttggtgg agttacactt gaagtagaag taaacgtact
    21961 taaaggtaaa ggcgaaattg tattaactgg aaaattagga gatgttatga aggaatctgc
    22021 gaagacaggt atctcttata taaggtcaat agtggacaag tttgatatag accctgaatt
    22081 ttataagacg aatgatattc atatacacat tccagaaggt gctgttccaa aagatggacc
    22141 atcagctggt ataactatgg ctcttgcagt aatctcagca cttactaaaa gacctgtgcc
    22201 tggaaatata gcaatgacag gagagataac tttaagaggt agagtcttag cagtaggagg
    22261 agttaaagaa aagttattag cagctcatag agctggtata acaaaagtat taattcctaa
    22321 agaatgtgaa gctgatttag atgaaatacc agaaaatgta aaagaaaaaa tggagtttgt
    22381 gcttgtagaa catatggatg aagtattaga acaagcttta ttaaagagtg gtgaaaataa
    22441 tgaaaattag aagttcagag ataactatga gtgctgtgaa taaatcacag tatccagcag
    22501 aaggaatccc agagatagca ttggctggta ggtcaaatgt tggaaaatca tcaataataa
    22561 atacattgct taacagaaga aactttgcta gaaccagtca aacaccagga aaaactagaa
    22621 ctataaattt ttatctaata aataatgaat tttattttgt agaccttcca ggctatggat
    22681 atgcaaagat agctaagtct gaaaaagaaa agtggggagg tataatggaa cgatatctag
    22741 aaagtagaca agagttatgt tctatattcc tacttgtaga tattagacat gagcctacag
    22801 cagatgataa gcttatgtat gaatggataa agcactttgg atataactgt gtagttattg
    22861 caactaaggc agataaaata tctagaggac aatatcaaaa acacataagt ataataagaa
    22921 aaaaattgca aatggaaagt agtgaaaaag taattcctgt ttcttcacta aaaaagactg
    22981 gtgttgaaga attatgggaa gagattgtaa atcaatacaa tcaacatgga tatgaaataa
    23041 cagtagatta aatttaaaat gttaaatatt gacataagat ttatttgaat aataaatgta
    23101 ataatagtta gttttaatta tattaatatt aaagtaaaat ataggatgcc ttaaaatagt
    23161 tttaatgaac ttttttttgg catccttatt gtttataaac aataaatatc agtaattttg
    23221 ctaaatacta ataaatttta gtaaggtatg ggaaaattag tataaaatag ttaaactaaa
    23281 aaattattga tttatgtagt cagtaataaa tagcatttaa gaaatagatt tatctgtttt
    23341 cctcataaag aaaacagtta gtataagccc tacaaaacat actgatgctg aaatccaata
    23401 agactgattg ctagctataa cataggctga tgtgtgactt ttaaactttt gattgtatgt
    23461 aagactttgt gcaaaaaaac tactaaaaaa tgctgttcca agagcaaatg ataaattacg
    23521 aatagttgca agaaaactgc ctccgtaccc ctgtttttga ggaggaacat ctgctaaaat
    23581 actactattg tttggtgaac taaatgctcc tagcccaagt ccaaaaataa ctaaacatac
    23641 aattaaaaga tacaatggag aatctgcttt taaaagtgcc attccaacta gtgagatggt
    23701 cataaatgaa aaagatgctg ttagaatgtt ttttgcaccg tgtttatcag aaagtgaacc
    23761 tgcaataggt gctataagta ccataataag tggatgtaca gtcattacat aaccagccat
    23821 cataggagat aaatttttta attgttctaa ataaaatgga agtagaaaag atactgccat
    23881 ttgaggaaaa taacaagcta ctccaatgat attgcctaca gtaaagtttc tatttttaaa
    23941 tagaggtagg tcaataaagc tttgttcaaa ttttacttct cttaatgcca acaataagaa
    24001 gattataagt gctgttatac ctaaatacaa tcttgtatta cctttctcat tcattgcaag
    24061 taatataagc gtagtgcaag atgcgaaaag tagaagacct ggaatatcaa agctcttgtt
    24121 ttgttcatcc aaaacaggtt taggcagaaa tttaatgcca agaaagactg ctataatacc
    24181 aataggtata ttgataataa aaatagaagg ccatccaaaa tgttctaaaa ttatacctcc
    24241 aattacagga ccactcatat ttcctatacc aactacagct ccagtgattc ctatagcttt
    24301 tcctttttca tttgctggaa atgcattgga aactatacca agcccagtag ccattaaaat
    24361 acttgctcca actgcctgaa agattcttga agaaattaat gttgataaat tgtttgacat
    24421 actacacaga aaagaaccta ttgtaaatat aaaaaatcct aatgtgtata gacgatttga
    24481 acctacttta tcgccaagtt ttccgaaaaa taacatagta gctgttacaa caagcatata
    24541 agctgttaca acccactgaa tttgtgacat gttaatttta aagtcagcag caattgtagg
    24601 atttgcgata tttagtatac ttccatcaag agtagacata aatacaccaa tacagatgat
    24661 aatcaatact atccattttt gtttcatgat aacactccaa tcttaataga ttttataagt
    24721 acgatataat tgtaaaataa acaacaaaaa aagcacctgt atattaggta ccttgaatgt
    24781 gtctaatttc atgaataaat acggtagttg aaggatttgt atagattact catgtaaaat
    24841 tacataaagg tactcatata ctattttctt ctaccatcca gattttactg tcggctttgg
    24901 aatatgacca aattatgcca taaggctcgc gggcttttac cgccgatagg gaatttcacc
    24961 cgtttatgaa gaaaaacaga tgtattttgt aatattattt taacataaaa ttataatgga
    25021 aacaattgga tttaagtaat atccagctgt attacaatac aaatatttca atatggacac
    25081 ttaaattgta tttatagata gaataaggca cagtatgaga atctataata attagataaa
    25141 attaacctgt tattagtatt agatggcaag ttttaaattt gtcaaaatca gaaagctgta
    25201 ataaaattct tataatatga atatcttaat taagagatat tgtaaattat gaggaggcgc
    25261 taatatggaa ggaaaggtaa agaaggcatt cccgggtgga aatacatcac aaggctcata
    25321 ttcttttttt gactatataa ttcctgaaaa tgtaaaaaga gttttttgtt taaagggtgg
    25381 acctggagta ggaaaatcct cacttatgaa aaaaatttat aaagagtttt tgcatagagg
    25441 atatgatatt gatttatatc attgtccttc tgacccaagt tcgttggatg gtttagttat
    25501 aaagaaatta ggcgtggtac ttatggatgc aactgcccca catactatgg acccaaagct
    25561 acctggagcc ttggatgaga taattaattt aggtgattac tggaatacag aagaattaga
    25621 aaagaataaa caagaaatat cagtttatga taaagatatt agtaattcat ttaaaagagc
    25681 atttaagttt ttaaaatcag cagaaccaat ctttagagac atagaagaaa aatattctga
    25741 ttgtatggat tatggaaaag taaatttggt cacagaagaa tttataaaaa ggttatttga
    25801 tggagttaaa agcacaggaa atctaaaaag agaaaagcat ttatttggtt cagctataac
    25861 tcctgtaggg tgtttagatt atacagaaaa cattttaaaa gatgtaaaga aagtctatta
    25921 tttagatgga gaaataggaa ctgggaaaac tacattatta aacaaagtat ataagaaagc
    25981 tattgaaaaa ggtttaaatg tagaagttta tcattatcca cttattccag agaaaattga
    26041 aactgtacta ttaactgatt tagatatagg cataactata agtacgactt ttaaagaaga
    26101 agatacaatt gatttaaatc agtttttaaa tagagaaaaa ctacttaaat atgaagaaga
    26161 tattaaattt gatgaaaaag ttttagatga tttaatttgt tgggcagtac taaatcttaa
    26221 gagagccaag tctaaacatg atattataga aagttactat agtcctaata tgagatttga
    26281 tgaagtaggc aaattaagag ataagttaat taaaagaatt ttaaaatatg aggaaaactt
    26341 ataaacgtat atgtttaaaa ttaatgttaa taataatata atttttagta aattggtgta
    26401 gctttgaggc tatgccattt tacttttttt tgctaaaaaa tgatattaat aatctccaaa
    26461 gtcattattt gtttttcata attattattt cctttcctaa tttatgtttt ttataatatc
    26521 acaacaatgt ttattgaaag tttatataat tttaagaaca tctaaaaatg catacttgat
    26581 attggtaaat tagtgatagg agttcaatgt atgatattat atactaaaga tgaattttaa
    26641 tatataactt tgatataata agcatatgta aatgtttaat atttaattaa agaaaattat
    26701 catataaaaa taaatttgta aggagcaata cagtatgaaa aaacaatatg tgtttataat
    26761 actagcaagt actattttag gtatacttgt tggaaccata tttagagatt atagcaatga
    26821 agaaacagtt tatacaagca aagacaagtc aataagaaaa gaaataaaaa tgacaagaaa
    26881 atctataaaa gaattaacca aagagaaaga caagttagat aaagaaatta attcaatgaa
    26941 acaaaatcaa aaaaattctg aagaaatatc agaaatagaa acacttagag atagtctatc
    27001 atattcagat gtaaagggta gtgggataat attaagtata gatgctatag atgaaaaaac
    27061 agggaatata gctaatagta tagactataa taagattctt gtaaaagtta taaatgaatt
    27121 aaaagtaaac ggaggaaaat acatagaaat aaatggtcaa agaattaatc aatattcaga
    27181 agttgtactt gcaggaagcc atataaatat aaatggagtt cctgtagcac aaccatatga
    27241 aataaagtgc attggagata aggagaaact atctaattat gtagataaag gtagtaaata
    27301 tttagatagc atacaaacca attatccaat gaaaataagc ataaaaactg aagaaaatat
    27361 ctctatgaaa aaaatgaata tacctaataa attaaagtat ataaagggtg attaagatta
    27421 tattagagga aagcagtttg ccaatgttaa taccagaaaa acttgcaaaa aaatataatg
    27481 tatttccagt tgagtttcaa gatgataatt tagttgtaga aatagaagat gaggatattt
    27541 atgctctaca ggacttgaga ttagctacag gtaaagaaat tatattgaag aaggagaaaa
    27601 aagaacttat aagtgaaaag attgaaaaat attataatag ctttgaactt gatgaggatt
    27661 atgcaaaaaa attatttgaa aatcttttag aaaaagctat aaaagaaaac gcaagtgata
    27721 tacatataga accatttaaa gaacatttaa tagtgagaat gagggtagat ggagaactaa
    27781 aggaagtatc aaagttttta gttgatgtct atccatcatt gtctacggtt ataaaattaa
    27841 aggcatcaat ggatataaca gaaaaaaggc ttcctcagga tggtagggtg gatataaagt
    27901 taggtggaaa tttaattgac attagagttt catcaatacc aactgtctat ggtgaaaaaa
    27961 tagttttgag gatacttaat agagatactt ttttaaaaga caaattagaa cttggttttt
    28021 cagaggaagc tataaaatct ataaatcgta taataaataa aagagcagga atattattag
    28081 tgacaggtcc tacaggtagt ggaaagacga caacagtata ttccttatta aatgatttaa
    28141 aaggaataaa taaaaatatt atgactatag aaaatcctgt agagtataag atggatggca
    28201 taagtcagat tcaagtaaat tcaaaagtag ggttgagctt tgatgtaggt cttagagcga
    28261 tattaagaca agacccagat ataataatgg tcggagaaat aagagatgca gaaacagcta
    28321 agatagcagt aagagcagct ataacaggtc atttagttat aagtacttta catactaatg
    28381 atgcagtatc ttccatagct agattactag aaatgcaaat accaccatat cttttaaatg
    28441 cctctcttat aggtgttata tctcaaaagt tggttagaaa agtctgcaat cattgtagcc
    28501 atgagattat gataaaagat aattttagtg gagatgtaaa tactaaggta gctgtagggt
    28561 gtgaaaaatg taatgataaa ggatactttg gaagaacagc aatttatgaa atcttagaaa
    28621 ttaatgatga tataaagaca tgtataagaa atatggagga ttctagtact attaaagatg
    28681 tggcacaaaa taatggaatg ataacatttg aagatagttg taaaagacta ataaatgaaa
    28741 aaataacgac attagaagag tgtttagtag taaatgaaat gatttaactg aattgtatag
    28801 ttaaacttcg tttggtcagt tgtctttatt taatctattt taattaagat gtttgagtat
    28861 aaattatatt taagtgaaat aaaattaaat gcattaaatt agaaaatatt aagtttattt
    28921 aattgtaatt aatataattt ggaaggtatt atagtacatg agattatcta aaaatatatt
    28981 ttataattta gaaaagtttt atttagtatt aaatagaatc agtgataaag aaattagagt
    29041 aatttgcaaa gagataggca tattgctgga atctggatgt gaaattacaa aaatatttga
    29101 aatcattgag agtcagtcaa gtaaaaaagt aaagaatttg cttagtatag tatcaaatca
    29161 tattcaaaaa ggtaactcaa tagcagaatt atttcaaata acaggtatat tttctaaatt
    29221 ctttataagt atgataaaag caggagaaac tagtggaaac ttagatataa taatgagtga
    29281 tttatctaat tattatgata aagaatacaa attaaaaatg aaaataataa ctatttcaat
    29341 atatccaata atacttataa tattatctat cttatcaatg ttgtttatat tcgtatttgt
    29401 aatacctaat tttcaggtgg tttttaccaa caatggaatt gaaccacctt taataactag
    29461 agttttaatg ggaatatcta cagtggttac aaataactta gcttatataa tatttagttt
    29521 tatattgttt tcaataggaa gcatttattt ctttataaca aatgataata taaaaaaatt
    29581 gattaattcg ttaaaattca aaataccttt tataaaaaaa attaatcagt tagtagctat
    29641 aacaagattt tcaagggcat tgtccgtttt aattagcagt ggaatacaaa ttgtggaagc
    29701 tatagacatg tcagctagtg ttatagacaa cgaatttatt tatgaaaggt taaagatttc
    29761 caataattat ataaaaaaag gaaatagcat aggtaaatct ttgaatttag caaatgtttt
    29821 tccaaaatta tttatttcaa tggcaaatac aggagaagaa agtgggaaac tagataaaag
    29881 tctaaatgta ataaataaat tttatgaaaa tgaattaaat aacaaaatag agcaaataat
    29941 gaaatttata gaacctatgc taattgtatt tatgggatta attattggta cttttatttt
    30001 agcaatggtt gttcctatgt ttgatgcaat tactaatttt tagagagaaa aataaatttt
    30061 attagatgaa acttttgaaa aggagagaat atttaattga taaatttgat aaataaaaaa
    30121 cgaaaaggat ttacacttgt tgaaatgatt gtagtagtaa ctattttagg cgttatatct
    30181 agtatagcat tagttaagta tagtaaggtt caagaaagtg ccaaattaaa tgcagactat
    30241 acgaatgctg ctaatatagt aaccgcagct agcatggcaa ttaatgatga tgaaaagaca
    30301 atagactctc taagtgtaga gacattgaag gaaaagggat acctaaatac tgttccagtt
    30361 cctcagagta catcaggtaa attcgaactt gtcataaatg atagcggaac agatataagc
    30421 gtaaatataa attctaagca attttatcca aaataatatt ttatattgat tgctgtaagt
    30481 tttaaaatta tttttattta agaaggagat ggctataatt aaaaaaattc taaacttaga
    30541 aataaatgat gattatataa ggcttgtatt tttaagaaaa agtcataaaa aagtttttat
    30601 agataaatca attataaaag agattaactt tgatataaaa aatgatagta attcgattga
    30661 gaagattaaa tatatagaag atgtagttag atttgtaaaa gaggagattg gtaaatcaaa
    30721 aatattatat aaaaatttat actttaacat tcaaattcag gatatagtca ttagaaatgt
    30781 tgaagttcta aatactaaga aaaaaagaga catattaagc atgattgaat ttgaaataac
    30841 acaatacatt ccaataaaca taaataacta ttcaataaaa tataaagtta taaattctaa
    30901 aaatgataaa ttgaatatac aagtaattct tttcccaaag agtattattc aattaattaa
    30961 gaacatttca gaaaatctaa atatgaatcc aaagactata aatataaatt ttgatatatt
    31021 acaaaagctt ataaacttaa atttaataga gaatttttca gaagaagggg tatttataga
    31081 atgtaaaaaa agtcagttaa ttataaatat aacaaaagat aaaaaaataa gagaaacata
    31141 cttgctatca aaagagggaa agtcatatga gttcataaaa agattattaa gggattttaa
    31201 gtatgtttat tactatggta tagaaaattg ttttattgaa gaatacttta aatatacaga
    31261 taaatctatt gaagtaaatc cattaagatt aaaagataaa gtaaaagtag aaaataattt
    31321 tgatgcagat ttagaagaca ataggataaa ttatataaat agtataggaa tgattattta
    31381 agtgaaagtg gataaaacaa taaattttct taatggattt aaaaaaacta aaccatgtaa
    31441 taaaatctat aaaataataa tagtcttaat tttaacgtgt attttattta aatcatttat
    31501 gtatgtgaaa tctataaatg aacttgaaga ttatataagt caaaataagc tagtggataa
    31561 atcaaagaac actttaccaa caacagataa aactagagag aaattttcta aaataaaact
    31621 taatgaaata aaaaaaatat atgaaacaat tggaataaat agtattacta aaatatcaat
    31681 agataaaaat aagctagaga tggaaggtgt gtgtagtgat ttagatgttt taaacaattt
    31741 aaggaaaata aagtacataa aatattatta catagacagt attgtaagag atggagaata
    31801 ttatagattt agaataaaaa gttagatggg tgattatttt tgagattaaa taatagagaa
    31861 aaaaatctac ttaaaatatt gttaatatta gttattatat tggcaagtga tatagcagta
    31921 agttatttgg aagaaaacct aactagtttg aagaatgaaa agcaaaatat aataaataaa
    31981 ataaataatc aagataatta tcaaataaag gataataagc atatagatga taaatatata
    32041 gaaagtgttg aattaaataa aaatgaagaa ttgaaaaata attttaataa ctcattttta
    32101 gataaaaaaa caaataaaga tatagtgtta ttagtagaaa atgaactgag agatattgtg
    32161 aatgtagaat atattaatca agaaagtagt ttagataatc acaataaaaa acaagttaat
    32221 ttagaaataa aagttaatgg agaacttgca aatgtgttga aacttgaagg tgtaatgaag
    32281 aagttaagac taaataataa acttgaaaag atagaaatta acaaattaaa agtcaataat
    32341 tttgatgttc aaaatattcc aaatgaatat aaacaagaaa aagacaatat tgttgaatgt
    32401 aaaatgacag ttagagtcat ataacaaaaa agaatagata aagtaaaaaa ctattatcaa
    32461 ttaataaaat tttatagagg aattagtttt acgataattc atttctacaa gagggattgt
    32521 tgatgatttt atcgaaatcc taattaaagt taatatattg taccaaaata taagtgaatt
    32581 taatagaata tttacttata ctatagattg attaataaaa aaatggtata ataacaaatt
    32641 gtactttaat ttaataataa gggagtggaa gtcatattgt tagggagaaa tgagctatgc
    32701 ccttgtggaa gtggcaaaaa atacaagaaa tgttgtttaa ataaagatat tgtttcagaa
    32761 agagcatgca gaaaaactga actttcacaa aaacaatata cagatttata ttcaaagtta
    32821 tatgattatt caagacagga taagtttaaa gaagaatgtg aaaaagctaa agaaatgttt
    32881 tatataatgc aaaatgatag tgtaaatgaa aaatttgaaa gattttttaa tacttattta
    32941 atacaagacc acataatgga aaataaaaag gttatgacag ttggttttct tgaagaaaat
    33001 ggtgcaaacc taagtcaatc agaagtatca atattaaaaa gtatgtttga atcatacgta
    33061 agtatttatg aggtaaaaga agtttctgct ggaaaaatag tattaaagga ctgtttaagt
    33121 ggaaatgaac tttgtacaga agatgtaaaa cttctgagaa gttttaaaat cggaagttgt
    33181 atgatagcta gaatagttga tattgaagga actaacatat tgatagatat aactataagt
    33241 atatcaaatg aggttaaaga tataatttta aaggatatta tgaatctatt caatcaatat
    33301 caagatgtat acaaagatat gaagtcgttc ttaatttatc atacacatat actatacaag
    33361 tatatacaac agcttttaga cccaagtata gctgaatatt taaagagaga aagagataaa
    33421 aacgatacaa aagttaattc agaaaatgaa ttagctgaag aagaatgtaa agttttagat
    33481 actcttaaag aaaatgtaga aaaagaaaat atagatgcat gtatagagtt ttggaatgaa
    33541 tataagaaaa atcatgaaaa tataaaagga gctgaaaatg gttgggcagc tgctgttgaa
    33601 tactatgtta aaaaagaagc aggacaacct ataactcaag ttcaaatatc aaagaaatac
    33661 gatataagct ctagtacact aggaaagaga tacaaggatt taaaaatatc ttaattaatt
    33721 ataaaaagct ttaagtcata gataaagaat ctatagtata atatatgtat aatgtttaga
    33781 aagaggtatt aataatgagt cttagtttag gaaatgcaat tgctgtatca acgaacttta
    33841 taaaatctaa cccagctgta cctgtgtaca acggagaaga aatatatgca gttatttatc
    33901 atatagaaat aggatataat aatggtgtat cacctgatac caaacaatat ataataatag
    33961 actataaaga gtttgattta tctatggata aaaaaaatga actaataaat attgctaaag
    34021 agtactgtaa atctaaaggt attgtagaaa acgaaaacct tgaaataaac cttttagaca
    34081 atgaagaagc agagaacttc ttagaaaagg tgtttaataa tatgaaggtt ataagaggtc
    34141 ttataactaa aaaaggataa ataaatggac tatataggaa tagaaaatat aacaccttat
    34201 gaaaatacat atgaatttag tgtatatgaa tatgatgatg aaatcacctt aggtagtgaa
    34261 aagttatatg tatgtgaatt aagggttgta ttgattaaag ttaattctct gtatgttgaa
    34321 agattgcata aatcagttga agcaatggtc ttagtaaaaa acttgaaaaa agatttagat
    34381 aaaacacttg ttgtaaacaa aataaagaat tttgtgctag atgagatttg ggtagaaaat
    34441 ctagtaaaag agaatataga agttatattt gtagaaagct aggaataacc ctagcttttt
    34501 tatattacaa tctaagagag gaaaacaata tgttaagagt atctaatgta aaacttggaa
    34561 ttgataaaga tatatcttta ttaaaagatg ttatacttaa gaagctaaaa ataaaagaaa
    34621 aaaacttagt caaatatagt atatataaag aatctataga tgctagaaaa aaaggaaaaa
    34681 tggaatttgt ttattctgta gatgtagaag ttaaagatga aaataaaata cttaactcaa
    34741 aaataaaaga tgtaacaaaa ataaaggaaa tcagatacgt aaatgtacct gtgggtgata
    34801 aaaaattaaa gaataatcct ttggtaattg gtagtggacc agctggcttg tttgcaggtc
    34861 tgcttttagc tcaaatgggt tatgaaccaa tcatacttga aagaggtctt gatgtagaca
    34921 gtagaaccaa agatataagt gatttttgga caactagaaa attaaaaaat aattcaaacg
    34981 ttcaatttgg agaaggtgga gcaggaactt tttcggatgg taaacttaca actagaataa
    35041 aagatatacg atgtagaaaa gtattagaag agttagttca gtttggagca ccagatgaaa
    35101 tattatactc acataagcca catgttggaa cagatatatt aaaaaatgta gttaaaaata
    35161 taagaaatga aataataagt ttaggtggtc aagttagatt taattcaaaa gtaacagata
    35221 tagttgtatc aaatgattct atacaatctg taataataaa tgatactgaa aaaatagata
    35281 cagatacaat tatattagct gttggacata gtgcaagaga tacttatgaa atgttgtatt
    35341 caagaggtat aaaaatagtt caaaaacctt ttgcaatagg agctagagtt gaacatccac
    35401 aagatttaat aaataaagca cagtacaagg atttttataa tcatcctagg ttaggagctg
    35461 cagattatag acttatagag catgtttcaa atggaagaac agcatatact ttttgtatgt
    35521 gtccaggagg tagtgtcata gcatctgcat caaatgattt tgaaatagtt acaaatggta
    35581 tgagtgaaca tgcaagagat aaaataaatg caaatagtgc atttttagta aatgtaacgc
    35641 cagaagattt taagagtgat aatccactag caggtgttca tttccagcag aagtatgaaa
    35701 aattagcttt tgaattaggt ggaaaaaatt ataatgcacc agttcagctt gttggagatt
    35761 ttataaacaa taagacttct ttgaatttag gaagtgttga gccatcatat agaccaggat
    35821 atacacttac aaatttaagt gaatgtttgc ctagcttcgt aacagagact atgagagaag
    35881 cgtttatatc tcttgataaa aaattgaatg ggtttgcaat gtatgatgct gttttgacgg
    35941 gagtagaaac taggtcatca tcaccaataa gaatagtaag agatgaaaat actttagaat
    36001 cagtgagtat taagaatcta tatccatgtg gtgaaggtgc tggatatgca ggtggtatag
    36061 ttacagcagc agttgatggt ataaaatgtg cagaaaaaat aatacaaaaa tacaccaata
    36121 atacaaaaat ttaacataaa cttaatgatt ttttaatatt taacatgaat ttaacattat
    36181 cactcctata atttgataaa atacaatagg ttataaaatt tttagataca gtaatctctt
    36241 tacaaggagg aaataatttg aacattataa taagtctaat gggtggatta ggtctgttct
    36301 tatatggtat gaaccttatg ggagaaggtc ttcaaaaatc tgctgggaca aagctaaaaa
    36361 agataataaa actacttact agtaacctat ttatgggagt tttggtaggt acaggagtta
    36421 cagcagtaat acaaagttca agtgctacta ctgtaatggt tgttggtttc gtaaatgcag
    36481 gaataatgac tttaaaacag gcaataggag ttataatggg tgctaatata gggactactg
    36541 ttacagccca attggtatct ttcgacttaa ctggtatggc cccagtagca ttaggtgtag
    36601 gtattatact ttatttattt ggaaataagc ctagaataaa aaatatagcc gaaatactta
    36661 taggttttgg tatattattt acaggtatgg attttatgaa gatggcagtg gagccactaa
    36721 gagactatca aggatttact gacttacttg ttacatttgg tagatatcca ctacttggat
    36781 tattattggg atttgggatt acagcaataa tacaaagttc aagtgcatct atgggtatgt
    36841 tggttgcact ggcagcagaa ggtctagtgc cattatcagc agcactgcca attctttatg
    36901 gccaaaatat tggtacatgt gtaacttcac tgttatcaag tattggtgct aacaaaaatg
    36961 cacgaagagc agctatgatg catctaatct tcaatgtttt aggaacagtg atattcttaa
    37021 tattcttgaa taaaccagta gtaagcatgg ttacaagttg ggacccaagc aatgttgcaa
    37081 gacaaatagc caatacacat acattgttta atataatatc tgtattgata cttttaccat
    37141 ttacaaatct tattataaaa ctagctataa agcttgttcc tgatagagca ggtgatatag
    37201 atgaagatga aactaaaact attaaatata tagatgatag aatgatagaa actccttcta
    37261 tagctcttgc aaatacgata aaagaagcac ttcgtatggg tgagaaggcg aaggaaagcc
    37321 taaatgcatc tatggaagct ttagtagaac attcaactga aaaaatagat aagacatata
    37381 ggcgagagag attaatcaat gatttacaga aagctatttt aaattattta cttaaacttt
    37441 caaaagcacc tttagatgat gattcaagag aagttgtgga tactttgttt aatacagtca
    37501 atgatataga aagaattggt gaccacgcta aaaatatagc tgaattatcg caagttgcaa
    37561 tagattcaaa tatttctttc tcagaagaag gacaatctga acttgatgtt atgtataata
    37621 gagttgtttc agcatatact tatgcattag aatcaatgag aactgataat gttgatttag
    37681 cttgtaaggt tataaaaatt gaagaacaag ttgatataat ggagaaatct tgtagagcta
    37741 atcacatgta tagattgaac aataatctat gtagtataga aaatggagtt atttatttag
    37801 acgtaataag taatttagag agaatatctg accatgctgt caatatagca caacaagtta
    37861 tagcaaagag attaggaaat gattaaaaat aattaattta aaataatata aaatttaaaa
    37921 tagaggataa ataaaagaga aactttaaat gatacgttta gagtttcttt ttttgtaaat
    37981 ttatttgact aaaattttta aatttataca tagttatagc atttagaaga atcgatttcc
    38041 tgataataaa tgatgagata tgtatgattt tgtggcaaac ttttaaaaaa aacacctata
    38101 ttttgtgtta taatctcttt aaaacgaata tgttgaaaag agggatttaa atgggaaaaa
    38161 taaattttga ttatagtaaa gctacagagt ttttttgtca aaacgaaata gatgtcatgc
    38221 aaccatatgt agatgttgcg cacgacatgt tacataataa aactggttta ggaaatactt
    38281 ttttaggatg gatagacctt cctaaaaatt atgataaaga agagtttgac agaataaaaa
    38341 aatctgctga gaagataaaa tcagactcag atgttctttt ggtaataggt ataggaggct
    38401 cttatttagg ttcgagagct gctatagata tggtaagtca ttcttttagg aatggactta
    38461 aaaaagagca aagaaaggct ccagaagtat attttgtagg gcataatata agctcaacat
    38521 atattatgga tttattagat ataattgaag gaaaggatat ttctgtaaat gtaatatcta
    38581 aatcaggaac tactacagaa ccagctctgg cttttagaat atttaaagat tacttagaga
    38641 aaaagtatgg taaggaagaa gcaagaaaga gaatttatgc aacaacagat gcaagtaaag
    38701 gtgcacttag acagttagct acagaagaag gatatgagac ttttgtaata ccagatgatg
    38761 taggtggtcg tttttctgta ttgacagcag ttgggttact tcctattgct gctgctggac
    38821 ttgatattga tgctatgatg aaaggcgcaa atgatgctag agaagcattt caaaatcctg
    38881 acttaaaaag taatgatagt tatagatatg ctgttgctag aacaatttta catagaaaag
    38941 gaaaagatgt agagttatta gtgaactatg aacctcaact acattatgta agtgagtggt
    39001 ggaaacagct ttatggagaa agtgaaggaa aagaaaataa aggtttattc cctgcttctg
    39061 tagatttctc aacagattta cattctatgg gtcaatacat acaagatgga aaaaggcttt
    39121 tatttgagac agtacttaat gttgaaaact gtaagagaaa tataactata agttcagagg
    39181 aagtagactt agatggttta aattatttag caggtaagac tgtagatttt gtaaatcata
    39241 aagcttttga aggaactcta ttggctcata cagatggaaa agtacctaat ttagtaataa
    39301 atatacctca actagatgag tataattttg gatatttagt ttatttcttt gagaaggctt
    39361 gtggaataag tggatattta ttgggagtta atccatttga ccaaccagga gtagaagctt
    39421 acaagaaaaa tatgtttgct ttactaggca aaccaggtta tgaaaaagaa aaggaagagc
    39481 tagaaaaaag acttaaataa ttttaaatag ttaaggttta attaagatta aaataatata
    39541 atgaaatcat caaaaaggag tttactcaaa atagatgatt tcattttttt tatgaaaaat
    39601 tgggaaaaat atattttgat aatttatatt atattaagat agggagtggt atgagatgtc
    39661 aagaagaaag aaagggataa gtttagtaat attagttgct ataataagtt caatacttag
    39721 tagttttcta acaataattt tagttaagga caatttagta agcaaatcta caggaagttc
    39781 tacgccgata gttgtaaatg atgatggtaa gagtcaaaat atttatcaag cagttgcaga
    39841 aaaagctacg ccatctgttg taggtattac aacaactagt gttgatacta gtaatatgtt
    39901 tgcaatacca actgaaacac aaggtgtagg aactggaatc atagttgatt caaatggata
    39961 tatacttact aattctcatg ttatatcaga tggtcaagct acgagtgtaa atgtattatt
    40021 caatgatggt tcaacaactt caggtaaagt agtatggttt gaccaacaac ttgatttagc
    40081 tatagttaag gttgataaaa ctggactaac accagcagaa tttgctgata gtgacaaagt
    40141 aaaagttgga gatatatcaa tagcaatagg taatcctctt ggattagatt ttcaaaaaac
    40201 agttactcaa gggataataa gtggattaga tagaactata caaacagaaa aaactaatat
    40261 gactggttta ttacaaactg atgcaagtat aaatgcagga aatagtggag gaccattgtt
    40321 aaatcaaaaa ggtcaagtaa ttggtataaa cacagcaaaa gcttctcaag cagaaggatt
    40381 aggatttgca ataccaatca atacagctaa gagtatagtt gaagaagtaa tcaaaaatgg
    40441 aaaatatgaa aaagtaactt taggcataaa aggtacagat gtatcaaatt atgaagcagc
    40501 aacaggtaca aaattaagta ctgataaagg tgtttatgtt gcagaagtaa tatctggttc
    40561 atcagcagaa aaagctggag taaaggtagg ggatattata actaaagtag gagatacaga
    40621 tataacaggt atgaatgatt taaataaaaa gttgtatact ttctcaaaag gtgctagtac
    40681 aaaaataaca gtaaatagag gcggaaaagc agtaacaata aatgtgaatt tctaaatatg
    40741 accagaaaga tagagactac atggtaaagt gtagtctcta tttttattta atttttatag
    40801 tatatacatc taaattaatt aaaatgatgt attgtttata gcttattgct atattttctt
    40861 ataaaaataa atttaataaa tatttaaatt taatttacaa aaacaatata aatatcataa
    40921 taaaataaaa ttttttaata ttactaaaaa tatatagaca aaataataac aaatatagta
    40981 ttatgtaatt gtagaaatgc ttttcatagg tatattctat gaagatgaat tgcataaaaa
    41041 tgaaaaaatg gaatggatat tatttagggg tgaaaaatca tgaatccatt agttataaac
    41101 ttacaaaaat gtagcataca tgatggacca gggataagaa gtacagtatt ttttaaaggg
    41161 tgtccacttg aatgtgtttg gtgtcataat ccagagagtc aaacatatac aaaacaagtt
    41221 ttgtataatg aagaaagatg ttcaaaatgt gaagcatgta taaatatatg ccctcataag
    41281 gcaatttaca aaggtgaaac aaaaatatgc ttagaccaag ataagtgtga gttttgtgaa
    41341 acttgcttag actattgtgt aaacaatgca agagagattg ttggtcaaga gtattctgta
    41401 agagatttgg ttaaagagat agagaaggat agaattttct atgaagaatc aggtggtgga
    41461 gtaactctat caggtggaga agtaatggct caagatatgg acttcatttg tggagtaata
    41521 aacatgtgca aatcaaaggg aatccatgta gcaattgata catgtggcta tgcaaagtca
    41581 gaaaattatg aaagagttgc taaatgtgca gatttgtttt tatatgatat taagcttatt
    41641 gatgaagata agcacataaa atttacagga aaatcaaatg acttaatact gaaaaatgtt
    41701 aagattttaa gtgaattagg ggctaacata aatataagaa taccattaat tgtaggagta
    41761 aatgtagatg atgaaaattt agaggttaaa aaaatgatag agtttttaaa gcctttgaat
    41821 atacaagcag taagtcttct tccatatcat aatattggta aacacaagta tgataaaatt
    41881 tataaaaagt atgaaggaga agaactacaa agaccatcag aagaaaaatt agaggaaata
    41941 aaaagactgt ttgaagcaag taatttcaat actaagattg gagggtaata aaatggcaag
    42001 aggaactttt gagagaacta aaaaattaag agaagaaagt attaatgcag aaccacacat
    42061 atctattgaa agagcagtac ttatgacaga agcttataaa aaatatgagg gaagtgtaga
    42121 gattcctgta cttcgtgctt tatcatttaa gcattatatt gagaatagaa ctcttagcat
    42181 aaatgatgga gaattaatag taggtgaaaa aggtgattct cctaatggag caccaacata
    42241 tccagaaatt tgttgtcata caatggaaga tttagaagta atgcacaata gagatataat
    42301 aaattttagc gtatcagaag aagctagaaa aatacataaa gaagaaataa ttcctttttg
    42361 gaaaaagaga caaacaagag ataagataat aaatgcaatg acacctgagt ggttagcagc
    42421 atatgaagca ggtatgttta cagagtttat ggaacaaaga gccccaggac atacagtttg
    42481 tggagataca atatataaaa aaggattttt agatttaaag aaagacatag aagcaagatt
    42541 aaaagagcta gattttctta atgatttaga tgcatataat aaaaaagcag atttagaagc
    42601 tatggcaata gcttgtgatg caatggttat attaggtaaa agatatgctg agaaagcaag
    42661 acaaatggca gaagaagaaa cagatgaagc taagaaaaaa gatttattac taattgctga
    42721 aacttgtgat gttgtaccag ctcacaaacc agaaacttat catcaagcta tacaaatgta
    42781 ttggtttgtt catatagggg ttactactga acttaatata tgggatgctt ttactccagg
    42841 aagacttgac caacatctaa atcctttcta tgaaagagat gtagaaaatg gaatactaga
    42901 tagagataga gcacaagaat tacttgaatg tttatgggtt aaatttaaca atcagccagc
    42961 accaccaaaa gttggtataa cattaaaaga aagtagcaca tatacagatt ttgcaaatat
    43021 aaacactggt ggaataaatc cagatggtca agatggtgtt aatgaagtta gttatataat
    43081 acttgatgtt atggatgaaa tgaaattgat acaacctagt tcaaatgttc aaataagtaa
    43141 aaagactcct caaaaattct taaagagagc ttgtgaaata tcaagaaaag gatggggtca
    43201 accagcattt tataatactg aagcaatagt tcaagagctt atggaagctg gaaaaactat
    43261 agaagatgca agacttggtg gaaccagtgg ttgtgttgaa actggatgtt ttggtaaaga
    43321 agcatatgtt ctaactggat atatgaacat tccaaaaata cttgaattaa cattaaataa
    43381 tggatatgac ccaattagta aaaaacaaat aggtattgaa actggagacc ctagaaattt
    43441 ccaatcttat gaggaactat ttgaagcatt taaaaagcaa ttacattata tgattgacat
    43501 aaaaatagaa ggaaatgctg tgatagaaaa tatatgtgca aaacacatgc cttgtccact
    43561 tatgtctaca atagttgatg attgtataga aaaaggcaag gattaccaaa gaggtggagc
    43621 aagatacaac actagatata tacaaggtgt tggtatagga actataacag atagtttaac
    43681 agcaataaaa tataatgtat ttgataagaa aaaattcgat atggatacat tgcttaaagc
    43741 acttgatgct aattttgaag gatatgaagc tatacttaat ttagtttcaa ataagactcc
    43801 taaatatgga aatgatgatg attatgctga tgaaataatg caagagatat tcaatgcata
    43861 ttacaatgag gtaactggta gaccaactgt ttgtggtgga gaatacagag tagatatgtt
    43921 accaacaact tgtcatatat actttggaga aattatggga gcaagtccaa atggtagact
    43981 ttgtgcaaaa ccagtttcag agggaatttc acctgaaaaa ggtggagata ctaatggacc
    44041 tacagcagtt ataaaatctt gtgctaagat ggaccacata aaaactggtg gaacattatt
    44101 aaatcaaaga tttgcaccat cagtagttca aggagaaaaa gggttagata atatggctaa
    44161 tctagtaaga gcatacttta atatggatgg tcatcatata caatttaatg tatttgataa
    44221 aaatgtactg ttagaggctc aaaagaatcc tcaggattat aaagacttaa tagttagagt
    44281 tgcaggatat agtgaccatt tcaataattt aagtagaaca ctacaagatg agataatagg
    44341 aagaactgag caaacattct aggtttgctt gtaaataaaa cttcttacta tataaaatcg
    44401 taactgatat aataaagtat aaatggtttg attccatttt taaaatttta gattaattat
    44461 gagctaactt tctaaatagg aagttagctc gttaagttta atgaaaaaat cgttaaattt
    44521 atatttagta aatcatacac atattagtaa gtaatacata caaaagaata atttattata
    44581 gttataataa ggttatattt tataaaaata agataatttt aagcagttaa aataaagtca
    44641 atttagctac tttaaaataa aactaataga aaaaaggaga tttgatatga aaactttagg
    44701 atttattggt tcagggaata tgggaagtgc aatgataggt ggcatagtac agtcaggatt
    44761 agtaaaggca gaagatataa ctgtatcaga tttaagccaa gttgccttag ataaagtaaa
    44821 agaagaattt ggagtaaata ctacaactga ttcaaaggta gctgttacaa attctgatgt
    44881 ggtaatagta gcacttaaac ctaatatatg cgaaaaggct ttaactccac ttaaagaatt
    44941 aatagatgca aataaaataa tagtatctat agcagcaggt aaaactatag aaagtctgga
    45001 aagttttata ggttcagata aaaaaatagt aagagtaatg cctaatactc cagcccttgt
    45061 tggcgaagga atgtcagctc tttgtaaaaa tagtaatgta acagatgaag agttaaatat
    45121 gattaaggct ctgtttgaat cttttggtga ggcagaaata gtatcagaat atttaatgga
    45181 tacagttaca ggtattagtg gttcttctcc tgcatatgta tttatgttta tagaagctat
    45241 ggcagatgca gcagtattag ctggaatgcc aagacaacaa gcttataaat ttgcatctca
    45301 agcagtaatg gggtcagcta agatggttct tgaaactgga aaacatccag gtgaattaaa
    45361 agatatggtt tgttctccag cgggaactac tatagaagct gttaaggtat tagaagaaga
    45421 aggatttaga gcagcagtta taaaatctat tgttgcttgt atagataagt ctaaagatat
    45481 gagtaaataa cagatgtaat taagtttact atatggtttc ttgaattgtt tttttagtgc
    45541 ttatttatat ctataaataa atgtatttgg tataagtaaa ataagagtaa tttactataa
    45601 aaaggaattt aatgattgag tgagaattta ttacttaaat attaataatt aaatagatat
    45661 atttttaact atatttgaga tatatcattg tgaaaaaata aaatttataa gtattattgt
    45721 gaggttataa gtagatttat ttaaaaataa atttatttat agccttttta aatttgaaat
    45781 aatattcata aggtaataaa agttacaaat attttcttcg ctaataagtt ttaaaatacc
    45841 tataatgttt tactttttat tataataaat acaataaata tattcttata taaattctat
    45901 gttagatata tggaaagata agaaccttga gattatgtta aaaaatctag attttatact
    45961 tataaaaagt ttgattttac aaccttacaa aagagaatca agataggaat ataattatct
    46021 ttttcataaa tatataaatg atatactaat attatagtat tattgatatt tgtattggag
    46081 gttgaacatg agggatgaaa ttttaagttt tgtaaatgaa tgtgtattat ttaacaactt
    46141 tgatgaactt aaaaaagaaa gtggcataat aacagaagat atagtaaaaa agtttaattt
    46201 aagtagaact caatcaagta gattattaaa tgatttagta aaatctgata atcttataaa
    46261 gataaacagt agacctgtta tttttttacc taaaaataaa ataaatgatg tagtaggacc
    46321 tacaaaaaaa agtatttatg aaaatttaga tgaacttaaa aatgagtgta aattattaaa
    46381 gcaagagact gtgtttaata gtatcatagg atatgataat agcttaaaag aagtaatcga
    46441 acaaataaaa accgctgtac tttatccaaa tggcggactt acaataatgc tgacaggtga
    46501 aagtggagta ggaaaaactt ttttagccaa gataatatac aaatatagtg taagcagtaa
    46561 tgtattagaa aaaaattctc catacaatgt gttaaactgt gcgcagtatt ataataattt
    46621 ggagttattg tctagtctat tatttgggca tgtaaaagga gcatatactg gagcaaatga
    46681 atctagagca ggtctaatag aacaatcaga tggtggtgtt ttatttttag atgaagtaca
    46741 tagattaaat agtgaaggtc aggaaaagtt atttacattt atggatacag gtacgttttc
    46801 taggattgga gagaatggag taattagaaa agctagggta agattaatat ttgctacaac
    46861 agaaagtcta tctgaatttt tacaaacctt tttaagaaga atacccataa atatttatgt
    46921 tcccaatata gaagaaagag ggactattga aaaaagaaag attgtagaac attttattta
    46981 tgaagaaagt aaggtacttg gtttgcctat agagataact caaattacat taaatgcgat
    47041 tttaaagata aaattcaagg ggaatatagg tgaatgtaaa aatgtaataa aatatgcatg
    47101 tggacgagct tatgcaaaaa atcaaagaag aaatggaaat atttttgtta ctcttcaaga
    47161 ccttcctaga aatctttata tagaaaatgt agatatattt caattccaaa gtggtaaaag
    47221 caaaagcatt atcttttctc ctaaacaatt tagtattgaa atgtcaaatg gaagaaataa
    47281 aagaaatata atctatcaaa gtttcataaa atgtttagat tactttgata gactagaaaa
    47341 aaatgaaata acaaaggaaa aatttagtaa aaagagttct aatctaatga ttagactaat
    47401 ggacaattta gtcttttcaa ataatgatga aaataataac gtacttatgg agcttataat
    47461 atcgataatg caggatatat ttagaaattt agaagttaat aacaatataa aatatgatgg
    47521 gaataatgta ttggcatttt cgtcttatct ttatttgaag gacgaatctt atcaattgtc
    47581 tgatgagtat aaagctttag aaaataaatt actaatatat ttaaaaaaag agagttacaa
    47641 agaatactct ataataagta aaatatcaac attaataacg aatagattgg atatgtatct
    47701 taataatgta gatacaatca taatgattat atttattaaa tcaacaatta taagaatgaa
    47761 atttaatcaa gttaatgcga ctattatagc acatggatat gctactgcca gtagtatggc
    47821 gaatgtatgt aatcggatgt tgggtaaaaa tatatttaca gctattgata tgcctataga
    47881 tgctactatt gctgatgtat caaaacaaat gtctagatac ctagagggag ataggataaa
    47941 gaatggttta attgtattat ttgatatggg ctctcttaat cttatatatg aagatttaaa
    48001 gaataagata aatagcccaa tgttatttat agaccaaata tccactattt ctgcactaga
    48061 agtaggaaat ttattaatgc aaggtaaaaa cattgaagag attgcagaaa ttatggatga
    48121 agaaactaaa cctaatatac aattgtatta tcctcaaaaa aataaagaat atgctataat
    48181 atcatcttgt tttacaggga taggtactgc tataaaaatc caacatctac tttccgaaag
    48241 tttaattgga atagttgatg tcaaaataat accttatgat tatgatagtc ttgtttctat
    48301 gggagataaa gaaccagttt ttgaaatgta tgatgtgatg gctatagtag gaactgccaa
    48361 tccaaatgtg aatggggtag attttatatt attagaggat ataatatcag gaaaaggaga
    48421 agatgatgtt tttagaatat ttagcagagt agtagaaaat gaaaaaataa agaacataaa
    48481 tgattctatt gtaaagaatt tttcattaat tagagtaata gatagtctaa ctattttaga
    48541 ttcaaaaaag ataatagaga gaatagaaga aggaattaat gctatagaaa atattcaaaa
    48601 gaaaaaactt tcaaatgata aaaagatttc tttatatgtt cacttaagtt gtatgattga
    48661 aagattagtt agacaaactg aaattgaaga gtatactgat atggatttgt taatcaaaaa
    48721 ccatcatagt gaagtaaaac taataaaaaa tgcatttagt gtgctagaaa agagttatag
    48781 tgtgcaaata ccaatttcag agataggata tatttataat attatctatg gtctaccaca
    48841 gtaaaataca agattacaaa ataagtgaat gaaatttaaa aaagtatgcc agtatttggc
    48901 atactttttg cttttataga taaatgagag tataaacaat aaaaatttta atgtattatg
    48961 gaggatttgg ggaaaatggt atctttgatg agaattgatg acagattgat acatggtcag
    49021 gttgcatatg gatgggcaac atcactaggt ataaatgtaa tactagttgc aaatgatgaa
    49081 gcaaaaaatg accaaatgaa agctatgtca ctgaacttag cgaaacctag caatgtaact
    49141 ttatatataa ggggggtaga ggaatctgga gaaatagtag aaaaatttgc ttcttcaaag
    49201 aaaagcaatg tattagtgtt agtaaaaaat accaaagatg ctttagttgt agctaaaaat
    49261 tcaggaggag tattaaaaga aataaatgta ggaggattaa gatatgagga agggaagaag
    49321 aaacttacag atttagttgc tgttgatgat gatgatataa ataactttaa acaaataggt
    49381 gatttaggga ttgatataga atttagaatg ttacctagag acaaaaagaa acaactatca
    49441 gatttaataa aataatttag gagaaagaga atgaaaaagt ttctaattgc aacacatgga
    49501 gaattgtcca gagagcttgt tgacacaagt aaattaataa ttggttcatt aactaatatt
    49561 gagtattttt gtatgacaac ggataaatca gcagacgatg ctgagaaaga aattagaagt
    49621 atattatcaa ataataaaga tagtgaagaa tttgttgtct taacagatgt ttttggtgga
    49681 agtgtggcaa acatatgtac aaacttactt ttacaagggt tcaaatttga attattgaca
    49741 ggagtaaatt taccaatgct tttatctata cttttattag ttgaggagga tacaaaacta
    49801 atagttaaat caggattaga ggaagcaaaa aatggaattg tttatgtaaa tgagttatta
    49861 gaaaatcaaa ataaaatcaa aaatgtaatg taatttaatg taaattaaac taagttaaaa
    49921 tggaggttca atatgttagt acaagctact atgttagcta ttatagcagg agttggtata
    49981 ctagatgggc gtatatttgg tcaatctatg cttgataggc caatagttac aggtatgtta
    50041 gtaggattag ttttaggaga cataaaatca ggaattatga ttggtgcaca gcttgaatta
    50101 atttggatgg gaattgcagg aataggtgca gctactcctc cagatgtagt aacaggaggt
    50161 gtattaggta cagcttttgc tatattatca ggtaatggtg cagaagttgc tttagcagta
    50221 gcagtaccag tagcagtctt agcacaatct cttggagtat tagttagaat aataaattcg
    50281 tacttttctc aaaaggcagt tttctatgct aaacaggctg attttaagaa agttaccatg
    50341 atgatgtggt tgccagtaat attattcttt ttaagtacat cagttccaac ctttttagca
    50401 attatgattg gtgctgataa agttacagca ttgataaatg caatacctaa agttatatta
    50461 gacggactgg gtgttgcagg aacattgttg ccagcagtag gttttgcatt gcttatggat
    50521 atgttacttt caaaaaagat gtctgtattt ttctttatag ggtttttgtt agcatcttat
    50581 ggtggattag atataactgc tatagcttta tttggagtat gtgtagcatt tgtactaaac
    50641 ttttatatca ataacaaaga aaataatcaa aatcctcaat tagcaatcaa tactttaacg
    50701 gaaggagaga ttgactttga ataaattaac aaaaaaagaa ttaagaagta tgttttggcg
    50761 ttcatttgct cttcaaggtg catttaatta cgaaagaatg caaaacttag gttactgtta
    50821 ttcaatgtta cctgcaataa agaagctata caataagaaa gaaaatcaag caaaagcaat
    50881 agaaaggcac ttggagattt ttaatacaac gacagtagta gttcctgcta tattaggtat
    50941 aacagcagct atggaagaag agaatgctaa taatccagaa tttgatgaaa gttcaattag
    51001 tgctgttaaa acagctctta tgggacctct tgcaggaatt ggtgattcat tattctgggg
    51061 aacatttagg attatagcag caggagtagg agtatcactt gcaaaagaag gtaatatctt
    51121 tggaccacta ttattcttac tattatacaa tataccagca tttgccctta gaatatttgg
    51181 acttaagtat ggttatcaag taggggtaaa ttctcttgaa agaatacaaa gagagggact
    51241 tatggagaaa ataatgtcta tggctacaac tgttggttta ttcgttgtag gaggaatggt
    51301 tgcaactatg ttgagtataa ctactcctct gaaattcaac ttaaatggtg cagaagtaat
    51361 tttacaagat atactagata aaataatacc taatatgtta cctttaacct ttgcatttgt
    51421 aatatactac atgttaaaga gaaaggtaag tgtaacaaaa ttaactatag gcactatagt
    51481 aacaggaatc gctttacatg ctataggttt gttatagaaa ttaattataa tttattgaat
    51541 atatagataa ggaaggtgta taaaatgaca atacaagatt atatgttaga aacaccagtt
    51601 agaatgagag aaattatatc taatgcagat agcttattta atgaagttaa gagaacaaat
    51661 ctaaaaaaga ttataataac aggttcaggt actagctatc actcaggagt gcaagtgcaa
    51721 ccatatttac aaaatttatt agatatagat gttgtgaaaa tgtatccatt tatgataact
    51781 gaagatacat tcaagtttga taatgaaaat accctagtag taggtgtatc tcaaggtggg
    51841 agtagttatt ctacatacaa cgctatgaag ttagctgaag ataagggctg taaaatagca
    51901 tctatggcag gttgtaagaa tgctttaata gatgagattt ctgattatat attaacagta
    51961 aattgtggtg aagaaaaatc tggagctaaa acaaaaggat attattgtac aaagttaaac
    52021 ttaatgttat taggtcttca aatagctaga gaaaaaggta taatatctag tgaaaagtac
    52081 aatgaggaaa taaataagat attagatgca attaatagat ttgaagcagt gtataagctc
    52141 tctaaacaat ggattgaaag aaacaaagaa aagttagtta attctaaaga aataagaata
    52201 ataggtcact ctgatatata tggagataca ttagaagcag cattaaaatt attggaaaca
    52261 atgagaatac ctgtaactgg gtatgagttt gaagagttta tacatggtat atataatgct
    52321 ataaatagtg attctactat atttatacta gatacatgaa aagaacctag agtaactaag
    52381 atgattgatg tactttctgg ttggacggaa aatgtatttg ctataggtag agatgttaca
    52441 gaaaatgata aaaatttaaa gattgatatc acagataatc cttactatca aacatttaat
    52501 tttatagtac ctatacaact aatatgtggg gaaataccta cattaagagg tgtagaccca
    52561 agtgttccaa aagatactag gttccacatg aagttaggta gcaagaaact gaataagtaa
    52621 caaaaaaaga ggttgtctca aaatagagat aagcctcttt tttactgttg aaatgatgaa
    52681 aatatatttg attttctata aaaaagagtg ccccatgaac taaaaagtta attttgagac
    52741 acccactttt atcttatttt aaactaaaat atttatatat tagtgtgcat tatttttttt
    52801 attgctgtct tccttacttg agcaagaatt agcacttgga catccagaac aaatagaaca
    52861 tccactacag acatttccgt tttttgtaga cttgaattta ttaaacagaa taaagagtgc
    52921 aaggactata attattccac ctatcaaagc ttccattatt gaattaccca taaatagtac
    52981 tccacctata cttttaacta taaaagccat tatccatgct agtataaatt gatatgcaaa
    53041 tgatgtaaac atcattttat tgccatattc ttttttcata gttgcaagtg cagctataca
    53101 tggagtatat aaagcagtaa atatcaagaa tgtatatgca gtaactccat taaatattgt
    53161 tggtaagaca acagttagat taccatatag tatatttaaa gagtttacta cgatttcttt
    53221 tgctccaaga ccacttaaaa tagcaactga agttctccaa tcatcaaaac caagaggttt
    53281 gaatatagga gatataatat gacctagagt agccaagaag cttacattta tatcttctgt
    53341 atatccaaaa acattgaatg aagaaagtcc ccaaattacg actgacattg caaacatgac
    53401 agtaacaact cttatcaaga aaccttttga tttattccaa gtatttttaa taagtgcatc
    53461 tatagtaggg attctatatt ctggtaattc taatataaat ggttcagcct ctgttttaaa
    53521 ggctgtttta tttaagaata atgcaactac aattgccata actataccca ccaaatacag
    53581 tgatgtagtt actaaagcag cattatgtgg aaagaatata gctacaaata gtgcatatat
    53641 aggtagcttt gctccacaag tcataagtgg tgcaataaga gctgtaactc ttctatcttt
    53701 ttcgctttcc aatgttctag ttgccattat agctggagaa gaacatccca tacccataac
    53761 tataggtata aaagctttac cagatagacc aacctttctc ataactttat ccattaaaaa
    53821 tgctgttctt gacatgtatc cactatcttc aaacaacgat ataccaaaga ataatgtaaa
    53881 tattaaaggg aagaatggta aagtaccacc aacacctcca attattccat caactataag
    53941 tgatttaaac catgggctag agttagataa catatcacta acaggtgcag aaatataagc
    54001 ctctataaga ctagcaaatc cctcttgtag tggtcctccg acccagtcaa aggtaaattt
    54061 aaataagagg aacaatacac caataaatat tggatatgct aatataggat tcaagactat
    54121 attgtctatc ttatcactaa tagatttctt ttgtgtatat gtagtttttg tacatctcaa
    54181 taaaatggat tctaattttt tatatgtttc tgtttcactt ccaaagtttt tctgatatat
    54241 aaaagctttt tgcgtagctc ccttaatctc ttcttctatc ctatcaacac catttttctt
    54301 ttttgctata attggaacaa caattactcc aagttcttca cttaattttt tggcatctat
    54361 attaactcct ttagattctg caatgtctaa catattaagc aatataacta taggcttgtt
    54421 aaattgcata agttgagttg ttaagtaaag gtttcttgat aaattagaag catcaactac
    54481 atttactatt acatcaacat cttcattttc taaatatgat ttagaaacct tttcttcatt
    54541 tgagaaagta tccattgcat atataccagg taaatcgaca acctttatct cttttccaag
    54601 aaatccttct tttttttcta tagtaacacc aggccagtta cctacatatt gatttgaacc
    54661 tgtaagtaga ttaaaaacag tagttttacc gacatttggg tttcctaata atgctacatt
    54721 aatcacgggt agctcctcct ctattattgt aaagaaatat ttttagcatc agattttcta
    54781 atcgcaaggt caaagcctct aaatctaatt ataattgggt ctccaagtgg ggcaaccttt
    54841 ttaacttcta tttcagtact atttatacat ccaagtgcaa gcaatctttt agataattta
    54901 atatctccat ctatactatt aataaatcct ttttctccta tttttaaatc gtaaacagtc
    54961 attattaaca cctcctaatg aaattcatta tcattaaaat tgtaacaagt atgatacaaa
    55021 aagtcaagat ttatagaggt aattgcacat tgaaataact aatatttatt ctaaatggat
    55081 taaaaatatt ttagtctaaa ttaggtgttt ttatatattt tgtattataa tgtaagatga
    55141 tagataaaat ttggaggagt taacttaatg aaaactagaa aaatgacatt tttaggtctt
    55201 atgatagggt atagtttagc tttatatgta ttagagacat atataccaaa tcctcttata
    55261 gttatatttc caggggcaaa attgggtttg agcaatatta taactttaat ttcattaatg
    55321 ttgttaggtg tcaaagatac tgttataatt gttactatca gggtaatttt gtcatcaata
    55381 tttgcaggcc ctttatcata tctactattt agtataggag gagcttatct gagtctttta
    55441 tttatgtatt tagcgagtaa aataaaagat ttatcactaa tagggataag cattataggt
    55501 gcaatagggc ataatatagg tcaattaata gttgcaagtt taatcataga aaatatactt
    55561 gctatagggt acttaccatt tatgttaatg gcatcattag taactggtat gtttgtaggc
    55621 ttagtatcca ggtatacaat acctaaatta aagcattttt atagtaagtt ttattgacat
    55681 aatattgaca aaatataata ttgtttgata aaatgtatat aaaaatatac aaatttgtaa
    55741 tagtggtgat tattatggcg aacaatgaat tagaagcgtt aaaaaatgag attgaagcag
    55801 ttagggaaga gataaataca tacatagaat atccagaaat atttcaagaa gagttagtag
    55861 aatcaagtaa gaaaatagat atattaataa ataaatacat gtacctaagc aaatagccca
    55921 cagttgtggg tttttttgta tcaaaaatta acagatggct atattttaca tatattaata
    55981 ataatattaa gatataaaat agtatttctg atgtgtaaat tatctgtagg acataagttg
    56041 taattaagtc aggagggttt tatattatga ttgatatagg aagtaaggag atagcaataa
    56101 ggttactatt agcactaata ataggaggaa taataggctt agagagagaa aaaataagac
    56161 agtttgcagg atttaggaca catatactaa ttgcaatagg ttcttgtatt gtttcaataa
    56221 cttcgattca attattcttt gattataatt tgtatacaaa tgctgacccc gcaagaatgc
    56281 ctgctcaagt attatctgga attggttttt taggtgcagg agcaatttta aaaaataaag
    56341 gtggagtaaa agggcttact acagctgctg ggatgtgggc aactgcatgt attggtatag
    56401 cagttggata tggttattat gaattggcaa ttctaggtgg attatttgta atgatagcat
    56461 tatttgtgct taggataatc aatacgtttt tatttagcca agaaaagaat gtattgatat
    56521 taaaattaag caatttggac tcgatacctt ttttatatga taaatttgaa aaaaatcaac
    56581 ttatcgtaag aaatatggaa atagaatgtc gtaatgaaga atactggaag gttaattttt
    56641 ttgtatctta tgctaagaga atacacttac acgacgttat gaaagaaata aatatgatag
    56701 aaggagtaat aaatgtagat tatttggact aaaatatata caatatattt tgtaaagtga
    56761 ataaaatata aaacaaatta aaatagaggt gtatgatatg ggaactgata gaagtacaat
    56821 agaagaaaag tacaaatgga agatagataa gatgtactcc agtaaagagg aaattgaaaa
    56881 agacataagt aaagtaaaaa atcttatcca agaagtaaaa gaatataaag ggaagctttc
    56941 tgagagtaag gagaacttat ataaagtatt aaatatctct gaaaatgcat ctaggattgt
    57001 tcaaaattta tatgtatata ctcatatgaa acaacatgaa gatactagaa ttaatgataa
    57061 tcaaggaaga gccactaaga cagaaatgtt atctactgat ttaggtgtgg ctacttctta
    57121 tatagttcca gaaatactgg cgatagaaga gaataagtta agtgaatact taaaagatga
    57181 gaagctatcc ttttatacaa aatatataaa ggatatattg agagataaac cacatacttt
    57241 gagtgaacga gaggaagaaa tacttgcagc tacatcagaa ttatcgacaa ttccagaaaa
    57301 tgtatacgat atgttagcat atgcagatat ggaatttcct gagatagaag atgaggaggg
    57361 gaataaggtt aagctttctc attcaaacta ctctttattt ataaaaagta agaatagtag
    57421 agttagaaaa gacgcttttg aaggtgaatt ttcaacatat gagaaatata aaaatacatt
    57481 tgcctcaacg ctttatggtg gaataaaatc agagatattt tacgcaaaaa ctagaaagta
    57541 taattcagca atagaagcat ctttattttc agatgatgta agtttagatg tttacaataa
    57601 tcttatatca gctatagata aaagtattcc taatctaaat aaatatgttg agcttaaaaa
    57661 gaaattttta ggattgaatg aaatacacat gtatgatttg tatgttcctt tgacagataa
    57721 atttgacatg gatataccat atgataaagc acaggatatc atattagagg cacttaaacc
    57781 tttaggagaa gaatacttga aggtcataaa aagtgctttt gatgaagggt ggattgatgt
    57841 atatgataat gaaggtaaaa aaggaggagc ttattcttgg ggaagttatg attcacatcc
    57901 ttatatatta atgagctata aaaatgacct taattctcta ttcactttaa ttcatgaatt
    57961 agggcactct gttcacagtc attattcaag aacaagtcaa ccatttttat attcggacta
    58021 taagatattc gttgcagaag ttgcatctac attaaatgaa ttacttctta taaattattt
    58081 attagaaaat tctaagtcta aggatgaaac tatatactta ttaaattatt atttagaaca
    58141 atttagaact acagttcata gacaaactat gtttgctgaa tttgaaaaaa ttgtacatca
    58201 aagggtagag agtggagaac cacttactgc tgatgaattt actaatatat actacaaatt
    58261 aaatgaaaag tattatggaa aatctgcaat agtagataaa caaataggaa tagaatgggc
    58321 gagaatacct catttttatt caaacttcta tgtatataag tatgccacag ggttttctgc
    58381 tgcaagtgct ttaagtcaac agatactttc agaaggaagt actgcagtag atagatatat
    58441 aaacttctta aaaagtggag ggtcagaata cccactagaa caattaaaat ctgctggtgt
    58501 agatatgacg aaaaaagaat ctatagagga agccttaaat gtatttgctg aattagttaa
    58561 taaactagaa aaagaattat aggatgtgat aggttgatag cttcaatgaa gacttctgat
    58621 aatatgagtt gtattatgtt tatatctgcc taaagtaact ttaaaaagtt aatctaatta
    58681 agaataaatc atataaaatt aagtttttac atgtatttaa caatatttac atttacttaa
    58741 ccctgctcta atattcattt aacaaagaat ctgtattatt aaaatataga aaaatgacaa
    58801 caaaaaatta aaatataagc gggggtaagt aaaatgttta aaaagaaaat aggcgttctt
    58861 ttagctagta caatgttagt tggagcttta gcagtaggat gtagttctaa ctcaggaggt
    58921 tcaggtgatt caggagattc aagcaaagtt tctgtttcag gttcaacttc aataggtcct
    58981 cttatggaaa ctatcggaga aaagtttcaa gaaaaaaatc aaggtgttag tgtagaagta
    59041 caacagattg gttcttctgg aggtataaaa aatgctatag aaggaacatc tgaaatagga
    59101 atgagttcaa gagatttaaa agatgaagaa aaaagtgctg gattaaagga aactaaaata
    59161 gcaatagatg gtatagcatt gataactaat actgcaaact cagtaaaaaa tctgacaatg
    59221 gaccaagtta aaggtatata tacaggaaag attactaact ggaaagaagt aggaggaaat
    59281 gatgcaccaa tagtaatagt atcaagagaa gaaggttcag gaactagaga tggattccaa
    59341 gaaattgtag ggtttgattc agaagaacta actaaagatg cacaaataag tgatggttca
    59401 ggaaatataa aaactacagt tgaaggaaat gaaaatgcta taggatatat atcatttgga
    59461 tatgttgatg agaaagtaaa tagtttaaaa ataaatgatg ttgaagcaac tgatgcaaat
    59521 gtaatagcta ataaatatcc aatatcaaga ccatttatat tagttaataa agaagatggt
    59581 ttgtcagaaa aaggtaaagc tttaatagat tatatattaa gtgatgaagg acaagcactt
    59641 gtttcagaaa aaggatttat taaagttaat caataacaag agttataata taaagtaaac
    59701 atataatacc ctgtgagata agctcataaa aatgatgctt taacttgcag ggtattgtct
    59761 attattgaat gtagaaatat aaatatcttt agataaaata ggtattttag tatcttatct
    59821 ctaagaatat ggaaatattg acaaaataat attacaatgt tagaataaaa aagaaattta
    59881 tgaaaatata taaaagattt ttaataaaaa tattttagaa actgagaagt atatcttatt
    59941 attgggcatc tggagatata tggagttagt ggtgcaaccg gctatgaata taatttttat
    60001 attgcatagt ctttttttgt tttaaaatta acaaaaatgt tgcaaaattt gaaaataaga
    60061 gtattagtcg ttaagatttt tattgatagg taaaattttg gcttttaaag tagccatttg
    60121 ttggaaaagg gaaatttttt taaaagaata atagtattat aataagaaaa taaagttttt
    60181 ataaacattg agatgcagaa tataaacctt ttgtaacaat atatttacca aaataataca
    60241 atttatttta tattataacc atataaatca tataaatcaa tactcaaact agccaataga
    60301 caagtttcta gaaaaataat aaatttatac gtgaaaatga ctttaagctc cattctccaa
    60361 caatcggaga ctttaattag tatttaataa tgaatcttaa tgtttaatac aatattcaag
    60421 aattattcaa aaatacttaa gtattatagt ctagtttgta aagatattat aaaataataa
    60481 taccagttat atatgaaaat aaaacattat aatttgtaat aattataaaa cttggaatta
    60541 taattaaaat acctttgaat ggagtggtgt aatgtataat ttactggttg tagatgatga
    60601 tgttgatatt ttaaacataa atcaaattta tttttctaat ataggtttta atgtatatac
    60661 atcagagact gctaaagatg ctatggatat agtagagagt atagttttag actgtataat
    60721 tttggatatt tcattgccag atatagatgg atataaaatg tgcaatgata taaaagaaaa
    60781 ggttaacata cctataatat ttttatctaa ttatgagcat gaagaagaaa aagttcgggg
    60841 atttttagct gggggggatg attatataac aaaaccttat agtttaaaag aacttgaact
    60901 tagaatatat gctcgtatga ggcagtacaa aaatattaca tcagttccta atgtgttaaa
    60961 gttttcagcg ttagtaataa atgtaaattc aagaaaagta acttttgatg gagaaagtat
    61021 agatttaact actatggaat ttgaaatatt attgtttcta gctgaaaaca aagaacaagt
    61081 attttcaaag atagagatat ataaccaagt ttggaaaatg cctgatattg gagatcaaca
    61141 tacagtgcag gttcatattg cacagatgag aaaaaaaatt aattctttaa gcagggagca
    61201 tcaatacatt caaaccgtat ggggaaaagg atataagttt gtaccataag tgagatactg
    61261 taattaataa atagttcttg ttttatttaa tacgactatg aaagagatgt ggttgatgca
    61321 atgaaaaagt ataatatact aaaaggaact ctcattgtat tgatagtctc tctgttggca
    61381 ataacaggat taaatcttct gtataaatat gataataaat atacatataa gtctattaga
    61441 gcaagtaatg gaattttaac tatagataat gatactttca ctaaagggca acttgtcttt
    61501 ttgatagatg actgggagtt ttataatcat aaaatattta aaccgaatga ttttacagag
    61561 caagatataa aaccagaata tgtttttata ggtcagtatc cagatttttc tatgagaaaa
    61621 gggaatcagt caccatatgg gaatgctact taccgtatga gaataaaaaa tgaaggcaag
    61681 gataagctac taagtttaga gcttcctgag attttttccg caagtgaagt atggataaat
    61741 ggagaaatgg tttctaaatt aggagatgta ggaacagaaa aatatagacc caaaattaaa
    61801 aattcagtag taagttttat tgcaaagaaa aatacagaaa ttataatcaa tgtatcgaat
    61861 ttttcacatt attatagtgg tttgtattat ccgcctgcat taggagaaac aaaggacata
    61921 agtaatatga tgttttatcg attacttttt tatagtataa tttgcttcac aacttttgca
    61981 atagctatat tttcattgtc tgtatggttt ctttcaaaca aaagtaaaat ttacttatat
    62041 tttggatgta tgtgtgtttt ctttgccatc catgtatcct atccctttgt acatttgtta
    62101 ggactgcctt tggtaagctt tacatatgcg gttgaagatt tgtcatattt tatggtagtt
    62161 ttatgtatta tttgtataaa tggaagtata tccaaaatag aagaaaataa agtgtataga
    62221 tttttaattt taccattagg aattacaatg agtatcatat ctatagtgat accaattatt
    62281 cttcttccat atgatatgta ctttgtcaac atatatggga agttaataga catatataaa
    62341 tatattgtat ttatatatat attaatgtct tcgctggttt caatatataa aaagacatgc
    62401 tctgagcata taagttctta tattttagtt tcagtaaaca ctgtttttgg aattagcata
    62461 ttatttgatg cagttacgag taatagattt gagcctatat ttacagggtg gcaaacagaa
    62521 tattgtggat ttgtaattgt tattttattt tctgttatga tgataaacag gaatagaata
    62581 ataataaaag agaatgaaaa acttacaagg aatcttgaac atgaagttga agtgagaact
    62641 aatgaactta caacattgtt aaatgaacgt aaaagattct tggcagatgt agcacatgat
    62701 ttaaaggcac ctgtttcggc tatacaagca tttatagatt tgataaaggt tggtaatatt
    62761 catgtagatg aagagacaag aacctatctt tatgctataa atcaaaagtc aaatgaagta
    62821 caaaatagag tacgtagttt gcaagaattt acatcacaag ataaaagcat tggtattagt
    62881 gaaaaaatat gtctgaataa ttttattaaa gagatatatg aaaataattt gccagataca
    62941 caagcatgtg gtgtaaactt tgaaacttac gtattggaga aaaaaatata tgcaaagata
    63001 aataaagaga tgcttacaag agcatttgag aatttaattt ataatgcttt gacctttact
    63061 ccatttgatg gaaagataat tttatcaatg gataaagaag atggatttgc aattattaaa
    63121 atttctgata atggaaaagg tatacctcca gaaaatatac caaaggtatt tgacagattc
    63181 tttacagaaa gagacaataa tgagccaaaa gggcaagggt tagggctata tattgtcaaa
    63241 tccattataa gagagcatgg tggagaaata tttgtagatt cagaactagg aaaaggaact
    63301 gtttttacaa taaaattaag tctatgtttt ttataataat agcttattta atataaaaga
    63361 ataatgatat ttgggagtga ttataatgca aactaagata ttgataatag atggagacaa
    63421 ggataattgc cagaagctaa aaggatttct ggaggaaaaa ggaataagta tagatttagc
    63481 atataattgt gaagaagctg ttggaaaaat atttagcaat aaatatgatt taatattttt
    63541 agaaataatt ctaagtgatg gtgatggatg gactctttgt aaaaaaatta gaaatgtaac
    63601 tacttgtcca attgtttata tgacttatat aaatgaagac caaagcattt taaatgcttt
    63661 aaattctggt ggagacgatt acttaataaa gcctctaaat ttagaaatat tatacgcaaa
    63721 agtaaaagct attttaagaa gaatgaactc atatgtaaat aataatgaaa ataatacaaa
    63781 attagaggaa tataatagaa ctagtggagt aataaagtta gaagataaaa taataaaatt
    63841 gactccaaca gaaaataagt tgttaaactt ttttatagag aatcctgaaa agactttgac
    63901 tactaaagag atatatgaac atgtatggat gaatgaatac ttagaggata actatagtgt
    63961 ggtagttgca gtgaatggat taagaaagaa aatagagaaa gattataaaa atcctcagaa
    64021 aattataaca ataagaggag caggatatta ttttaataag gaataataaa tatattaata
    64081 tcattaataa ttgttataaa tgtgaaatac taacgatatc taaactaaat tattataaaa
    64141 tagctgactg taatttaatt gataaatcct attcttctag actttgccag ttaaattaca
    64201 gtcagtttta ttatataaaa aaatgcgtaa tggaactatt attttataga ttatatttga
    64261 aaagatggat aaattgtata tctaaatcta tata
//
LOCUS       DAEPUT010000009        63979 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.009, whole genome shotgun sequence.
ACCESSION   DAEPUT010000009 DAEPUT010000000
VERSION     DAEPUT010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 63979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.009"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(269..1423)
                     /locus_tag="KRL22_000714"
     CDS             complement(269..1423)
                     /locus_tag="KRL22_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1271234.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(1426..1893)
                     /locus_tag="KRL22_000715"
     CDS             complement(1426..1893)
                     /locus_tag="KRL22_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1271235.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDIQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(1907..2395)
                     /locus_tag="KRL22_000716"
     CDS             complement(1907..2395)
                     /locus_tag="KRL22_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271236.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(2409..3740)
                     /locus_tag="KRL22_000717"
     CDS             complement(2409..3740)
                     /locus_tag="KRL22_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH1271237.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(3754..5319)
                     /locus_tag="KRL22_000718"
     CDS             complement(3754..5319)
                     /locus_tag="KRL22_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1271238.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(5488..6273)
                     /locus_tag="KRL22_000719"
     CDS             complement(5488..6273)
                     /locus_tag="KRL22_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1271239.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRIIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(6440..7639)
                     /locus_tag="KRL22_000720"
     CDS             complement(6440..7639)
                     /locus_tag="KRL22_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HBH1271240.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDSYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(8162..9499)
                     /gene="xylA"
                     /locus_tag="KRL22_000721"
     CDS             complement(8162..9499)
                     /gene="xylA"
                     /locus_tag="KRL22_000721"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBH1271241.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLESILNRYIYEVDTISNK"
     gene            complement(9595..11145)
                     /gene="xylB"
                     /locus_tag="KRL22_000722"
     CDS             complement(9595..11145)
                     /gene="xylB"
                     /locus_tag="KRL22_000722"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBH1271242.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            11353..12513
                     /locus_tag="KRL22_000723"
     CDS             11353..12513
                     /locus_tag="KRL22_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH1271243.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYKDNQNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(12669..13073)
                     /locus_tag="KRL22_000724"
     CDS             complement(12669..13073)
                     /locus_tag="KRL22_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1271244.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(13094..13576)
                     /locus_tag="KRL22_000725"
     CDS             complement(13094..13576)
                     /locus_tag="KRL22_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1271245.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(13596..14405)
                     /locus_tag="KRL22_000726"
     CDS             complement(13596..14405)
                     /locus_tag="KRL22_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1271246.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(14398..15177)
                     /locus_tag="KRL22_000727"
     CDS             complement(14398..15177)
                     /locus_tag="KRL22_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1271247.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(15177..17255)
                     /locus_tag="KRL22_000728"
     CDS             complement(15177..17255)
                     /locus_tag="KRL22_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBH1271248.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(18055..18576)
                     /locus_tag="KRL22_000729"
     CDS             complement(18055..18576)
                     /locus_tag="KRL22_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH1271249.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNNYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLN
                     IPIVGFDELREDK"
     gene            18742..19308
                     /locus_tag="KRL22_000730"
     CDS             18742..19308
                     /locus_tag="KRL22_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1271250.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSYS"
     gene            complement(19830..20699)
                     /gene="gatY"
                     /locus_tag="KRL22_000731"
     CDS             complement(19830..20699)
                     /gene="gatY"
                     /locus_tag="KRL22_000731"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH1271251.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIRDVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(20719..22635)
                     /locus_tag="KRL22_000732"
     CDS             complement(20719..22635)
                     /locus_tag="KRL22_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBH1271252.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIKNTNATKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSGVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(22638..23558)
                     /locus_tag="KRL22_000733"
     CDS             complement(22638..23558)
                     /locus_tag="KRL22_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBH1271253.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGANVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(23660..24412)
                     /locus_tag="KRL22_000734"
     CDS             complement(23660..24412)
                     /locus_tag="KRL22_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1271254.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(24804..26249)
                     /locus_tag="KRL22_000735"
     CDS             complement(24804..26249)
                     /locus_tag="KRL22_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH1271255.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDKNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEEARYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYENVIRTNGEELREK"
     gene            complement(26271..26624)
                     /locus_tag="KRL22_000736"
     CDS             complement(26271..26624)
                     /locus_tag="KRL22_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1271256.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(26653..27900)
                     /locus_tag="KRL22_000737"
                     /pseudo
     CDS             complement(26653..27900)
                     /locus_tag="KRL22_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(27908..28225)
                     /locus_tag="KRL22_000738"
     CDS             complement(27908..28225)
                     /locus_tag="KRL22_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1271257.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            28467..30380
                     /locus_tag="KRL22_000739"
     CDS             28467..30380
                     /locus_tag="KRL22_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1271258.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNFQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IDSVEVVNYIDNNVDINIAKDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYNQM
                     DTKSLSNYIDEHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLENVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIN
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIKFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(30503..31657)
                     /locus_tag="KRL22_000740"
     CDS             complement(30503..31657)
                     /locus_tag="KRL22_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBH1271259.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDVTYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDKNNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(31937..34552)
                     /gene="mngB"
                     /locus_tag="KRL22_000741"
     CDS             complement(31937..34552)
                     /gene="mngB"
                     /locus_tag="KRL22_000741"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH1271260.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHHEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVNAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEIGHMLEKAYEVCDMVDNDFYTIQINENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKIAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(34681..36621)
                     /gene="mngA"
                     /locus_tag="KRL22_000742"
     CDS             complement(34681..36621)
                     /gene="mngA"
                     /locus_tag="KRL22_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HBH1271261.1"
                     /translation="MEFKKITNENLVFLKQKIKTKKDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEASFAAMTLETPIENWESVDPNNKVELI
                     FLIAVPENKGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIVLAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSTSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIHKKIRY"
     gene            complement(36751..37476)
                     /locus_tag="KRL22_000743"
     CDS             complement(36751..37476)
                     /locus_tag="KRL22_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1271262.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(37739..38509)
                     /locus_tag="KRL22_000744"
     CDS             complement(37739..38509)
                     /locus_tag="KRL22_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HBH1271263.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLIQ
                     ERVYEHAMLCDKEVKIWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(38511..39938)
                     /locus_tag="KRL22_000745"
     CDS             complement(38511..39938)
                     /locus_tag="KRL22_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1271264.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            40329..41051
                     /locus_tag="KRL22_000746"
     CDS             40329..41051
                     /locus_tag="KRL22_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1271265.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            41248..42915
                     /locus_tag="KRL22_000747"
     CDS             41248..42915
                     /locus_tag="KRL22_000747"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBH1271266.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMNDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(43011..44330)
                     /locus_tag="KRL22_000748"
     CDS             complement(43011..44330)
                     /locus_tag="KRL22_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1271267.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYADKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVDVK"
     gene            complement(44371..45117)
                     /locus_tag="KRL22_000749"
     CDS             complement(44371..45117)
                     /locus_tag="KRL22_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH1271268.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(45361..47370)
                     /locus_tag="KRL22_000750"
     CDS             complement(45361..47370)
                     /locus_tag="KRL22_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1271269.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLGDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLRHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSING
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(47808..49241)
                     /locus_tag="KRL22_000751"
     CDS             complement(47808..49241)
                     /locus_tag="KRL22_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH1271270.1"
                     /translation="MSFKKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(49257..50681)
                     /gene="ascB"
                     /locus_tag="KRL22_000752"
     CDS             complement(49257..50681)
                     /gene="ascB"
                     /locus_tag="KRL22_000752"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH1271271.1"
                     /translation="MALRKDFLWGGATAANQCEGGYKEDGRGLANVDVTPQGKDRFPV
                     LAGKMKMFECDDEHYYPAHEAIDMYHNYKEDIKLFAEMGFKCYRMSIAWTRIFPTGVE
                     DVPNEEGLKFYEDLFDECLKYGIEPVVTICHFDVPMYLVKKYGAWRNRKLVDLYVKYC
                     EVIFTRFKGKVKYWLTFNEINMILHLPFIGAGLYIEEGENEEQIKYQAAHHQLVASAL
                     VTKLAHNINQEFKIGCMLAAGNTYPNTCNPLDVWKSIEKDRENYFFIDVQSRGEYPTY
                     ALKELERKGINIVMEEDDKKILKENTVDFISFSYYSSRLTSADPKVNILTEGNVFASL
                     KNPYLDASEWGWQIDPLGLRITMNSLYDRYQKPLFIVENGLGAVDNPDENGNINDDYR
                     IDYLRAHIKAMIDAVELDGVDLWGYTPWGCIDLVSASTGEMKKRYGFIYVDKDNDGNG
                     TLKRSKKKSFAWYKKVIESNGEEL"
     gene            complement(50768..52684)
                     /locus_tag="KRL22_000753"
     CDS             complement(50768..52684)
                     /locus_tag="KRL22_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1271272.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGGVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQILITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQELITVLA"
     gene            complement(52758..53618)
                     /locus_tag="KRL22_000754"
     CDS             complement(52758..53618)
                     /locus_tag="KRL22_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1271273.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(53969..55156)
                     /locus_tag="KRL22_000755"
     CDS             complement(53969..55156)
                     /locus_tag="KRL22_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1271274.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(55170..56561)
                     /locus_tag="KRL22_000756"
     CDS             complement(55170..56561)
                     /locus_tag="KRL22_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBH1271275.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIAPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLKL
                     GWYITEIAMIFTAIGIISGIASGLKQDDIVNSFISGAGDLMTAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(57156..58856)
                     /locus_tag="KRL22_000757"
     CDS             complement(57156..58856)
                     /locus_tag="KRL22_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1271276.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(58828..60231)
                     /locus_tag="KRL22_000758"
     CDS             complement(58828..60231)
                     /locus_tag="KRL22_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1271277.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELDEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGMYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(60496..60987)
                     /locus_tag="KRL22_000759"
     CDS             complement(60496..60987)
                     /locus_tag="KRL22_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1271278.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEADLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(61013..61825)
                     /locus_tag="KRL22_000760"
     CDS             complement(61013..61825)
                     /locus_tag="KRL22_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1271279.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLSKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(61838..62797)
                     /locus_tag="KRL22_000761"
                     /pseudo
     CDS             complement(61838..62797)
                     /locus_tag="KRL22_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            complement(62915..>63979)
                     /locus_tag="KRL22_000762"
     CDS             complement(62915..>63979)
                     /locus_tag="KRL22_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1271280.1"
                     /translation="QELINKTFGCCRFVYNKYLAKRIEVYKNDKETFTYKQCSSDLTN
                     LKKELNWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKFKSKKINRFSYKTNFTNGN
                     IMYCGQYIKLPKLGMVKIRDKQVPQGRILNATISKEPSGRYYVSLCCTDVDIEAFENT
                     NNHIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLK
                     VARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIKNRKLSRSISDVSWSEF
                     IRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRD
                     INASINILKEGLRLITIQNK"
BASE COUNT        20723 a        11595 c         7001 g        24660 t
ORIGIN      
        1 ggttttatat aaataaatcc ttaagtaaat attacatttt aactgttagc attacacttt
       61 tgtaacatat ggaagactat tataattata atggaaatat cttaaaataa aagcatgatt
      121 tacttctttg tataaacaaa gaaaagaagc tcctaagaag cctctaatct atacaattat
      181 tcttctctat aaaaaaccaa aatacacatt gattgtggca aatacagata ctataaacaa
      241 gtgatattac tactatatat taaaacaatt attcctgaag ataattcaat aagactatca
      301 agcaataagc taagcatcca aaaagactta ataccattaa tgtataatta tacccaatat
      361 taatgctcaa aaaaccagca acagttggaa taatcagaga tgaacctccc ataaatatac
      421 ttaaagctat taattggcta ctacttctaa gttttttagg agaaacttca aatattaatc
      481 tttttgaagt aattaaaatt aaaggagtag aaaacacttg aaaaacacac agtataataa
      541 tgatatttga atcatttgtt aaagcaaata atagaaactg aactgttatc ataatagcac
      601 ttaattttaa taagtttaaa ctgctatatt tttttaataa ataagaacca gccagatatg
      661 ttggtatctc taacaatgac tgtaaagacc actttaaaga tatctgagaa tttgtagcat
      721 ttaaagctat cattttatct attacagtac agttatttgc taccaccatt gagtataata
      781 agaataaaat acatactagt aagatatatt ttttatcttt taataattca ataatatctt
      841 tattagttac atttattttc ttattaatct tttcaatatc aggtaataat agtatattta
      901 taataagtaa tactacaatt aaaccaatcg ctacagataa tccaaaatat gagaatctaa
      961 gaatcaagta agatgctacc atacttccaa tagcccatcc aatcgaccca aaagtcttaa
     1021 taaatgacaa ataattatta atattatctc cacaacctat tatccatgta tcatataaac
     1081 tacagcaagt atttaataat cctcctgata aagcaacaag taataagtat attataaaag
     1141 ttgcagattc agtagaaaac ataataactg atgcaattcc ataaactgat aaactaatta
     1201 aaacaatttt tttcattgtt tgatacttat cagctaatac tccaaataat aattgaaata
     1261 atatattggt tattgcataa ctcgataata taattcctct ttcaaacgct gagtaaccca
     1321 attttgataa gaaaggtgtg aattttgttg aagcaaaggc aaaaataata tatgagaaaa
     1381 aatagaatat gataaattta aatttaatcg ctttattaat cataatcaat caaaattgat
     1441 aactttaata ccactatttc cttcctgatt taagtttgaa agatgatatt ttaccgtatt
     1501 aggattctct acaataacta aaggaatata taaagtattt tcaagtaact tattatcaat
     1561 ttctactaac ttttccccca tattaacttc ttgaccttgt ttaacttcta atttaaagtt
     1621 ttcttttttt gttgttgcac tatccaatcc aatatgaata agaatttgaa tatcattttg
     1681 caatttaatt cctatagcat ggttagtttg agcaataaaa cttattactc ctttagtcgg
     1741 tgatttaaga atattgtcct ttgctatcat agcaaatcca tctcccatta ccttagttga
     1801 aaatacttta tcaggaattt ctccaagatt aattattttt ccatcaatgt aggaattaat
     1861 tgtaattgct tctttttttc ttttaaagaa cattatagac actcctctac ataattaact
     1921 ttattctaat tatcattaca aataacgata ttaagcatac tgcaattgag gaaaaaagag
     1981 ccttatagct ctttccccat tgtagttctt taatactgct tatgatttgt ttaattccaa
     2041 caaatttata aatataggta aacatgataa caatagttat tgtgtaaatt tggaatatct
     2101 gccctaataa gactaaatag aaagcaatca tgttttcttt tatctcttta ttctttttta
     2161 tattgtaaat aacatatgca ctgtatactg cactaaagtt agagattaaa tttaaacttg
     2221 cattaacatc attgtttaaa agttgtgaaa atgaaatatt tgtaaataat gatgtcaatt
     2281 ctaaatacac tatatataaa acaggtaata ttagaaaaca aaccataacc actgaaagaa
     2341 atatattttc atcttttaat actgctgtga tattttttat tttatttgtt atcatgtttt
     2401 tgttctcctt atttaaaagt tggccagaaa tccttattag ccacaatcat ttcatctaag
     2461 atttcttttg ctacttttgc acttggaaca gttttactca tagtaaacga ctgccataat
     2521 ttttgataac ttttttctat ccatgcttct acagctaatt tttcagaagc aacttgttgt
     2581 tccattaaac ctttttggaa agttggaatt ttacctatag acataggttc aaccatatct
     2641 tttccaacaa ggcaaggaat ttcaaccatt gcatcatctg caaaattttc aatagctcca
     2701 ttattaggaa caatcagtaa aaatctttcc tgagtattaa atgctaatgc acaagctaat
     2761 tcaacaataa attgagaatg ttcacttgca tcaaaccatg tatctcttgc tgtgccattt
     2821 tttataattc tttcacattc ttcgaatgta tccttttctc ttctatccat aatttcattt
     2881 gctcttgtat aatttggatt agcatgttca acagtttcat cagccattaa ataatatttt
     2941 aaataagtat taggtaatgt agtcggttct atttccaata aatcctttgc tgctctcata
     3001 gtttctaacc aactagattc tttgtgttga ccttgaggtg taaattcctc atatcctttt
     3061 ttagcacaat attcttgtaa tttaggcatt aaatcatttc cttctttgtc cttaatactt
     3121 gtccaccacc cgaaatgatt caatccataa tatctaacat caaagtcttt acgagaattt
     3181 aaacctaaaa ctctagcaaa tatttcctct aaacatactg gcatatcaca aatattaata
     3241 attcttgaat ttggtcttaa tacacgacat gcttctgcaa ctatagctgc tggatttgaa
     3301 taattaagca tccaagcatt tggagaatat ttttccatat aatcaatcat ttcgattatt
     3361 ggacctattg ttcttaatcc ataggcaatt ccacctgccc cacaagtttc ttgaccaaca
     3421 accccatatt ttagtggaat tttttcatct tgttcacgta aagcatataa accaacacga
     3481 atttgtgcca ttacaaaatc aatatcagta aatgcttctt ctggatttgt tgtataacta
     3541 aatttaattt ctggattttt ctctctaaca attattgcac atgcttcagc aacttttctt
     3601 tgtctctcat cattattatc atataattta attgattcaa taggaaattt agcaacactt
     3661 tcaattaaca ttgttacaat tccagcagta taagtactac ccccaccagc aattagtatc
     3721 ctctgtcttt ttctttccat ctttccttct cctttataat aaattttcaa attcttctct
     3781 tacacttggt actgaaagcc caataataat ctgaatagct tttccattat gcactaaacc
     3841 atgtgcacct actgccttaa aatcttcttc tttagaaata attgagtcat ctttcaaggt
     3901 taatctcaac ctcgtagcac agtttgtaac atctacaaca ttttctgctc caccaactaa
     3961 ttttatgtat tcagaagctt gttgagaggc tttactcaat ttatttcctt tttcatcttt
     4021 agtttctaag tattcatttt tagtatatag ttttgtttct tcactatctt cctctctacc
     4081 aggagttttc atatcaaact tcttaattaa gaaagtaaat acaaagaacc agataaatga
     4141 aaatataatc cctacaacaa cttgaacaac atataccttc cagtgataca ttccaagagg
     4201 aagccaattt aatacaaccc agttaataat tcctccacca aaatcaccaa caactcctag
     4261 ggcaaacgaa atcgtttgca agcatgcatc taaaaatgca tgtactagga ataaaagtgg
     4321 tgctacaaat aaaaatgtaa attctaacgg ctcagtaatt ccagttaata ctgcagtaag
     4381 agtagcagga atcattaaac ctaatacttt tttctttttt tctggctttg cagttacata
     4441 gaaagcacca aatacaccta atgaaccaaa caccttcgat aatccggata atgaaaatcc
     4501 gattggatac atttccttta gagtcttagc tgaagtttga aagtcctgaa tatgagtagc
     4561 ccaatatact gatgtaccac ctggaacaac aacactatca taacaaattg gtgcatatac
     4621 aaaatgatgt aatccagttg gtattaaaat cttttgtaag aatgcataac accaaactcc
     4681 tatatttcca ctatttataa aaaacgtttg caaatgtcta ataacatttt gaatatgagg
     4741 ccaaataaaa caagttaata atgcaactgg tatcataaca aagaaacaaa ttgcaactac
     4801 aagtgatgag cctctaaata atccaataaa atctggcagt tctttatcat aaaatctatt
     4861 atgaatataa atgacaatac ctgatattaa caaagcacca accataccag tatctaatgt
     4921 tttaatacca gcaatgctta caagtccact tccagcactt atttcagctg cgaaatcaac
     4981 tccaaagctt tttccccaaa aacttaacat agaacctaca aaataattaa aagtcaaata
     5041 cgttgctaaa gcctccatac aagctcttgc ttgttgcttt tttgcaagtg ctattggtaa
     5101 agaaatagca aataataatg gtaattgatt aaataccatc caagctccac tagatattac
     5161 accccaaaat tggtaccaaa tattttctgg tgtagcaagt gaacccataa ttgactgatt
     5221 ttgaaataca attgagaatc caaccattat cccagcaaaa gcaaataata gtgttggtgt
     5281 aaacattgcc cctccaaaac gttgtatttt cttcatcata taaattactc ccctcctcat
     5341 atttttagtt tatctttggc cttagatatc tattatttta acaggttaat aaatatatac
     5401 aatctttagg gtacattcgg agcttattca cattcaaata agtttttgca catttttatg
     5461 ttcaaattct cataaaaaaa agaatgacta caatttgcaa tcaatccctt ctgtaatcat
     5521 tctatgcctt ttataaatac tatatttaat aaataataac tcaatcaata taaaatataa
     5581 cattgtcaat ttataactag ggtgcatttg taaaaatgag atattagtcg ctgaaatata
     5641 aattgattca tcacttaaat cagtcaatgt attattttta aactctgtaa ttgaaattat
     5701 tttagttcct attaatttta atcttctagc aatattaagt gtattctcat tctcaccact
     5761 tagggatata ataatcataa catcattttt actgacaata ttgtaaaaag aatcatcaaa
     5821 tgttcttccc tcaaaatcat atattatttc ttgacatgat aagaacattc tctttatctg
     5881 ttttgcaacc acattttgaa tatcacctga accataagcg tatattattc ttgattcata
     5941 aagaagttta cacaatgcat cataatcttt atttttttga tcttcaacat acttaattat
     6001 tgaattacat gcaatatcaa atgactgatt ttctatgaca tgaacctttt ctgattccca
     6061 gcttaataat actttaaact cactgaaacc ttttaaatct aattttttaa caaatcttgt
     6121 aatagttgca cgagacacat tacatttcat agcaagttca tttattgaca tcttactaca
     6181 atgtttttta tttgcagtta tatatttcca tattaataaa tctgtatcat tcaatttatt
     6241 ataatttaaa aaaatcattt cttctaatct cataaactat tacccccttt aattaaaaat
     6301 cgtcataaat attataccaa tattcaacat taaattacag cgtattctta tatttactat
     6361 ttagcccata aaattgacta taaaaaatac tgctataatt gatgtttaaa aaaatgtagt
     6421 tttaatttta ttcttttatc taataattaa tattttcaag ttctagtgct tttcttatac
     6481 aattatcatc tttaaaatca gcagtccttt tacaatcttt tactttaaat tctggaatag
     6541 ttttaaattc ctcatcacat attccattct tatttaaata catacaactt gccattctaa
     6601 ctattagacc actatttttt aaattaaaca atacagggtc tatacaccct ccatctccgc
     6661 cagtagtttc accaactaaa gtcgcaaatt tattttcttt acaaaacatt gcaaatgact
     6721 ctgatgatga atatattttt ctatcaacaa gtaagtatat attaccctta aattttgaat
     6781 catctgtaga ttttatagta taggaagtat cttcaaaatc attaaaatct tttataattt
     6841 ctttaggtgc attttccttt acacttgctg gtaaattttc tacaggattt aattttatat
     6901 ttcttgcatt tgtatatttt tttactattt cattattatt tctataaatt ctataaccat
     6961 ttattttgac atcatttttt atgagtttag atacgattcc ttgccaataa ctatcacttc
     7021 cacctaaatt acctcttata tcaataatta aagctttatg tttttctaaa gtgttaatat
     7081 aatctccaat tatttttaaa tcattattta tagagccatt ctttgatgac attgatggta
     7141 aatacatata tccaatctga cccttaataa catcctttaa aattaattct ttttttacaa
     7201 aaatatcatc tggcattttt attttaagat tcatagagtc atatctatcc acaacttttt
     7261 tatcattaag aaaatcatac caatcattat tagagtatga tttcttaaaa agttcatatc
     7321 ttttcttatt atctattact tctgtgtgtt tattatttaa atcagataat atagatgaca
     7381 gttcttctat aaattcttca tcattttcag tgttttttat tcgttttgta tattcatcct
     7441 tatttgctaa ccaatcaata ttattaagcc tcttatttac acctagatat ggatatcctg
     7501 tctttacaac attatacaca taattaaagt catccacctt ttcctcttca gacaactgat
     7561 tcttttgaga ataagtagaa ttacctaata atattataaa tgctaaaata attactaaaa
     7621 ataatacttt ctttttcatg taattctcat ccactttcag attttatatt ttaatacatt
     7681 gtatcattat tttattatca cctaaacagt taaaagaaat tcttgaagat atattccact
     7741 attattctat ttaaaaattt ttatttgtat tttcaaaatt atttcatgaa agttataaaa
     7801 taacaattat attcaaatat ctattttact gctatatcct gaaagtaaat tcttatcagt
     7861 gatatactaa aaaagatatg ctaaaaaatt tatccattat aatgacttaa atttagatac
     7921 tttactgatt tttatttatt agttgagaaa gatattgata attaaaaata ttgataacta
     7981 tagaaatgat tattttttat agaaatttta aggatataaa ctaattatac ttaagtctat
     8041 atccttaatt tatcatgatt atgagaattt ttacaaatac ttatctttgt ccgttttaga
     8101 ataaaaacaa gaacatatcc tacttatttt attcaaacat ccaagtttaa ttactacaca
     8161 attacttatt agaaattgta tctacttcat atatatatct gttaagtata gattctagca
     8221 tttcttgtct tccagactta ttctttataa ctggcatttg cagtgcataa gattctaact
     8281 ctttaaatcc aaccttacct tctactatat ccttacctat accttcacta aaacttgcat
     8341 atctttcttt agtaaagttt tcaaatacct catcttctaa taatttatga gctattaata
     8401 atccctttgc aaatgtatcc attcctgcaa tataagctag gaataagtct tctacctcaa
     8461 aagatgctct tcttacttta gagtcaaagt taaaccctcc tggtgctatt ccaccttgct
     8521 ttaacacttc atacatagca agtgttgcat catatatatt tgttggaaat tggtctgtat
     8581 cccaacctaa taataggtct ccttgatttg catctatact acctaaaaca ttgtttattc
     8641 ttgctatatt taattcatgt tggaaagtat gtcctgcaag tgttgcatgg tttgcttcta
     8701 tattcatttt gaagtattta tccagattat actttcttaa aaatcctaaa acagtagcag
     8761 tatcaaaatc gtattgatgt ttagtaggct cttttggctt aggctctatt aagaattgtc
     8821 cagtgaatcc tatttcctta gcataatcta cagccatttg taagaatctt gcaaagttat
     8881 ccatttcaag ttctgtatta gtgttaagta aagtttcata accttctctt ccaccccaga
     8941 atacaaaatt ttctcctcct aagtacttag ttatttccat agctttttta acctgagctg
     9001 ctgcatatgc atatacatct gcattacatg ttgtagatgc accatgaaca aatcttggat
     9061 ttccaaacat attggcagtt ccccacaata actttatacc tgtcttttcc atattaactt
     9121 ttatatactc aactatttca tctaatatct tatttgtctc ttctaaatct cttccttctg
     9181 gtgctatatc tctgtcatga aaacagaaat actcaattcc catcttagac ataaattcaa
     9241 atcctgcatc aactttaatc tttgctatct caattgggtc tgttatatta ttccaaggtc
     9301 tctctactgt ccctactcca aatgggtcat taccctctcc acataaagta tgccaatagc
     9361 tcattgcaaa tcttaagtgt tctttcatag tcttattacc taccacttgt tcaggattgt
     9421 agtatctaaa tgctaattca ttgtcagatt ttactccttc aaattttatc tgtcctattc
     9481 ctttaaatat ttcactcatt tcatgtcctc ctaatatttt acacatataa tatatgtagt
     9541 atgttttctt aatttaaaac tattttctat ctttattttt ctttttaagc taatttaatt
     9601 atttattttt gcattaacta cttcatctaa taacttaaag tcatctttca aagatttgta
     9661 tattctttta tacaatctat gatatatatt gtatgtatct acattttcac ttattggttc
     9721 taatttagtt gaagttttta ttatagcatc acatgctttt tgtatatttt catatattcc
     9781 agctcctact aatgcaagaa ttgcaactcc aagtgctggt ccttcacttg aatttatagt
     9841 atatacatct tgattaaaca tatctgcttg catctgtctc catactttac tttttccacc
     9901 tccacctgag gctcttactt cattaacgtc tatattaaga ttctctatta tatccataca
     9961 gtctttaaga ctatatgaaa caccttccat tattgacctt gcaatttctt ttttagaatg
    10021 gattggagat aatccaaaga acacacctct tgcataaggg tcaagatgag gagttctttc
    10081 tcccatcata tatggtaagt aaagcaatcc attacatcct gttggtactt gacttacttg
    10141 attatttata atctcatata catcttcacc taaagaattt gaaacttcca cttcactttg
    10201 acagaaatta tctttaaacc attttaatga caatccagct ccttgagtaa ctcccataac
    10261 atgccatgta tttggtattg catgacagaa agtatgaact ctaccttctt tatcaatttt
    10321 tggctctttt gtataagcaa atactacacc tgatgtacct atagtagatg aaactactcc
    10381 atctttaact attccatttc ctatagctcc tgctgcttgg tctccagctc ctcctaccac
    10441 tattgttcct tctttaagcc ctgtcaaact tgctacatct ctagtcacat aacctgtaat
    10501 ctcttgtgat tcataaactt tacctaaaag atttttatct atatttaact tttctagtac
    10561 ttcatcgctc caatctcttt ttcttatatc gagcaactgc ataccacttg catctgatac
    10621 ctctgtagca tattcacctg tcaatttgta tcttatataa tcttttggaa gaagtatttt
    10681 attagtattt ttatatatat ctggttcatt gtttctaacc cataatatct ttgatgctgt
    10741 aaatcctgta agtgctggat tagcagttat ttcaatcagt ctttcttcac ctactaaatc
    10801 agttatctcc tcacactctt ttactgttcg ttggtcacac catattatag agtttctcaa
    10861 tgttttacct tcattgtcca gcataactag accatgcatc tgccctgata atccaattcc
    10921 ttttatacat tcactgctta tatttgaact ttgaactact tctcttatag attcgactac
    10981 agctttccac caatcatttg catcctgctc tgcccaacct gatttctctt gtataagagg
    11041 atattcatat gtacaacttt ttatagtatt tcctagttta tcaaataaaa ctgttttagt
    11101 acctgatgta ccaatatcca cacctaatac atactccaac ttcatccctc cttgaatgcc
    11161 acttcataac tatcgttttc ctatcctaat ttttttatat tttaggtata ttttacttgc
    11221 tttatttttg ttagtatatt aaactaactt atgaactaat aataaaatat ttaattatct
    11281 ttgtcaatgc aaaataacct tttatttttg tgtaaaaagt attacaatat tattttaagg
    11341 aggaatatca aattggttac tgataaatac actattcgag aaatgaatga aagattggta
    11401 cttgaacaaa ttataaaaaa tggtcctatt tctagggcaa gtatagcttc tactatagga
    11461 ttgaataaag caactatatc cgctattacc aaaaaactta ttgatgaatc tctagttcat
    11521 gaaatcggaa ttggaaatag tactcatagt ggcggaagaa aacccatatt attagtattt
    11581 aataaatgtg cagggatttc tttaagtatg gacattggat acgactatat attttcttct
    11641 ctatcttact tagatggaac tattataaat tctaagaaat taacagatat acaagtaagt
    11701 aaagacaatg ttatacaatt gatagatgaa attataaata gttataacat atccaaaata
    11761 gacactcctt ataaggtaat tggtcttact ttggctatac atgggattac ttgtgaaaat
    11821 aaagtattgt ttactccata ttacaatctt aatgagattg acttatatag catccttagc
    11881 aaaaagtatg actttcctat tcatatagaa aatgaagcaa acttaacagc tttagctgag
    11941 aatacttttt caactgtaca taactcacta cttagtctca gtattcacag tggatttggt
    12001 tcaggcatta taataaataa taaattatat agtggcagaa atggtatgag tggagaaatt
    12061 ggtcacacta tcatcatgcc taatggtaaa ctatgtcctt gtggaaatcg tggctgttta
    12121 gaacagtatt gttcagaaaa aaaggtattt gaacagcttt cttctttaga aaatattcct
    12181 aaaatagatt ctgatatagt aaagcaacta tattataaag ataaccagaa tgccaaaaaa
    12241 gttattcatg agttttgtag ttacttaaca atagctataa ataatgctat tacaacttat
    12301 gctcctgaaa taatatattt aaatagccaa ataattagtg atatccctga gatattacag
    12361 attacaaaag atatgttagt tagctctttt aacaaaggaa taaatataga aatttcatca
    12421 ttagggtctg aggcatctct atatggtggc tctgccgtaa atatcaagag ctttttgaat
    12481 atacaaaatt taactttaat taatgaaata taagggttat gactatatac agccataacc
    12541 ctttaaatta tacattctaa aattagattt attatatagt ttatgcaaga ttagctatat
    12601 tttttaaaaa ttgtatatca attaagtatt aacataagta tttcgtttta aatattaata
    12661 taatcttcct actcatcatc agataataaa cttgcatttt gttcaaccat agaaatatta
    12721 tctttaccta ttttctctaa ttttgctgcc aattcctttg tatctaaaaa agctgattca
    12781 ataaccatac ctaaatttag ccctgaaata attttaattc gactgtcatt attggctact
    12841 aataaagcag cattgcatgg agttccacct agtaaatctg ccattataat tatttctgaa
    12901 ctttccttgt acacttctaa agcttttttt aatttttcta ttgttccttc tattccatca
    12961 tcttgtttca tatttacagt aggataatct atagaatccc ctattatcat ttttgcagaa
    13021 tttaagactt cttcagccat attgccatga ctcatcaaaa taatactatt cactttaata
    13081 cacctcttta aatctataag atgtctacaa gataagtttt cttatcatca ggcgtcatta
    13141 tagttgtaat ttcaattcct tcatctaaaa gtcttttaaa tgcttctttc tcttcttcag
    13201 taacactgat attaggtctt agaactgttg tatcttttct acttgacata tttcctacat
    13261 ttatattatg tattttaaat cctgcctcta caaatggaat aaggtccaca ggagacttaa
    13321 caattaataa tacattttgt ccttcatact ttcctgcagt aatatttttt atagcagtct
    13381 cttctgtaat tatagatgac gctatacctg caggtgtagc cattcttaaa acttgttttt
    13441 gaacagaatt gttagctact gcatcattta ctaccattaa tcttgtaaca cccaatttat
    13501 tactccacat agttgcaact tgaccatgga ttaaacggtc atctatacga atatttttaa
    13561 tacctttcat ttccatatct aatatcatcc tttccttatt ttaaaatacc taatgcatat
    13621 aaaattattg aaacaaccat tactcctaaa attaagtata taggttttat attcttttta
    13681 agagcccaat aaacaatcac aactaaaatt gcaggaacta acccaggcat aatttggtct
    13741 aatatttctt gacctttcat tgtaaaatca ccttgttgaa agttcaaagc aacattagct
    13801 tttacaactg aaggtattaa tgcacctaca accattaaac ctaaaataga tgtactctca
    13861 gttaaaatct ttaaactttt ttcaattgaa gatattagct tagtacctga tgtataacca
    13921 gcattaaata gtggtatact taataatttc aatgctacac tcactacaat ccacagtaag
    13981 attccaaatg gacttccatc tatcgccata ttagctgcta tagctccaaa aattgtccac
    14041 ggaataacga caaataaact atctcctaaa cctgctactg gtcccatcaa gcctgtttta
    14101 attgaagcaa cagcctcttc agtctcttca cttgataact cctccattgc tacattaata
    14161 cccaaaatat aaggggcaac ccaaggatta gtgttaaaaa attgtaaatg atttaataca
    14221 gcactttgta acttttctgg attatctttg tatactactt ttaaaaaagg tagtactgca
    14281 taacagtatg ccaaggcctg catcttctca taatttgaag aaacagaact agtaaaaaac
    14341 cagcgccata agacactttt tttcaccttt tcatttgatt tatttaatga taccttatca
    14401 ctcatcttcg tccatacctc ctactacagt atattgttgt tcttgatttt ccaaattctt
    14461 tttgtaaatt ataagtgcaa ttgctccacc aattaaagct acacctaata atggtacttt
    14521 catatatact gctaaaacaa aaccaattac taagtaacta aaatactcct tagcaggaag
    14581 atatctaagt aataatccta tccctactgc tggaagtagt cctccagcta ctgttaaacc
    14641 acctgttaac cattcaggtg tatatttcaa aatggtatta attaaagaag gtccaaatat
    14701 tacagataga gcaactggaa tacctgttgt agctgctgtt aatagtactc ctaacatttg
    14761 catataggtt atatttttat aatttccttt tttagctcca tcttctgctt tatgaactag
    14821 ccatatacca atagtatttc taagaacatc taattgtacc atcaataaag caactggaat
    14881 acctatagag attcctacag atgcttcttg cttagtcgta atagttataa atgtggctac
    14941 tatacttgct gtttgataat caggtattga tgctccacca aagttactaa tacctaatga
    15001 taatagctgt aatgtacctc caatatataa ccctgtattt atatctccta agataagacc
    15061 agtaataaaa cctgctgtta ctggttgata tgttccaaac attgttgaat ttttttcata
    15121 gtttataaaa aatccatata gtacgattaa taataattgc cataattgtg gctccattat
    15181 gatttcacct ctcccaaaat attttttagt tctttaaaat tataactgga atcttgcttt
    15241 aggaaaatag gaatttcttc cagtgggcat tcaacttcat aagttttccc accttcataa
    15301 ctaactccac taaatatatt ttcccatgta tgtccttttg gtaaatatac ttttctactt
    15361 ctatctttat aattcattat tggagctact aaaatttcat ctccaagcat atatgtatta
    15421 tccacctccc aagttttatc atcttcagga aattcataaa ataaagttct cataactggt
    15481 gttccatctt catgcgcttc tttcatcagt ttttttaaat aagtttttaa gctctctcta
    15541 atttttatga attttgtaag aattacttca acttcttcac cataagacca tatttcatta
    15601 ggagctccag ttaccattga gcctccacct ttatttgata atggtttact atgaggcaat
    15661 ctatctccat gcattctcaa aattggtgaa aaagtagcat attggaacca tcttaccata
    15721 agttctctaa attctgggtc tttaggattt cctccatgga aacctccaat atcagtagtc
    15781 caccatggta tacctgccag tcccatattt aaccctgtat ttacttgatt attaaaagct
    15841 tcaaaactag aatcaatgtc accagaccat actaaagctc catacttttg agctcctgcc
    15901 caagctcctc ttacaagagt tacaacagac tctatgtcat tatgtaaacc atcataaatc
    15961 atttttaaat aatcaatagg ataaatatta ccacaactta aaacatttcc ttttttatat
    16021 ctatagttat caaaatcata cacagaatag ccaggttcag ctacatctaa ccaataatag
    16081 tcaatcccaa gttgtttata atttttatct attctatccc aaacatattc tcttgcattt
    16141 tcatttgtca tatctacaaa gactgtattt ccttgaattt gcattgtcat tctaacacca
    16201 cgattaacat tgactaaata gccattttct aaataatcat tgtagttttc tgcatcactt
    16261 tgaactgtag gccatacaga tactattggt tctactgaat actcttcttt caatttttta
    16321 actaattctt taggattttt ccaataatct aagtcaaatt tatattcacc ttgcttaggc
    16381 caatgaaaat agtcaattgc aattgatgaa agcttaattc ctcttttaga atattccttc
    16441 acaacatcta aaacttcttc tgaagttcta tatcttagtt tactttgcca tagtcctaaa
    16501 aggttttcag gcatcatagg aacagttcca gtaacttgag agtaattttt atttaactct
    16561 tttgggcttt ctccacaagt aatccaataa tctataaaat ttgtagaaaa catcttccat
    16621 tctgtcatat ttttagcaaa agatactttt ccaattcccg gattattcca taaaagtcca
    16681 taacctagac tagaaatata aaaaggaact gatatttgag aatttctttg ggctaactcc
    16741 aaaacagtat tctttaaatc taaaaattta tgttgatatt gtcccattcc aaaaatcttt
    16801 tcagaaggct cagattcaaa tctagtagtt acttcaaatt ctccactata gcttggtcga
    16861 tattctcttg attttaactt tagagtagag ttaaagtctt tggtaatctc aattgtccct
    16921 acatcttctc caccatcatc atgttttaca gctcttaatc gaatatattc tttcaataat
    16981 atttcatttt tatcattata aaaagtaatt ctatctctat ggtctaagac agcttttatc
    17041 tttccatttt taatgattgc acttccatct tcatttttat taattgtaat atcatcttta
    17101 tttaacttag gtttttcgtt aagagcatag ttttcatcaa caaaattttg gtctacaaac
    17161 gacctaatac gtaaagagtt ttttccccat gcttctattc gcaatagttc attgtcaaat
    17221 cttttttcaa tatagtcttc agatattttt atcacggcta cctcctaaat caatggtata
    17281 atattctatc tttgtgtagc ttaagttaaa taatgtcgtt tagtatcgtt atttataaat
    17341 taggttttat atataattca tttgtacatt aaactaactt accaataata tactttattt
    17401 gactttgttt gtcaatcgct ttccggattt tagtaaaatt ttctaatatg ttgcttgaaa
    17461 gtcgttctta atatctttta tttatacttt taatatctgt gatgatacct atatacatct
    17521 agttttttta aaacacatac aggaataacg tttgcctatt atgtagataa tatcggactt
    17581 gaaaatatgt atagtgacct tataaataca gataataata tattagatat tgttcaaaac
    17641 aatggatttt ataattataa ataatttatg aaattattta ataaaatata taattgtata
    17701 ccaagtcaaa aacgacaaca aataaataaa actaaaaaag atgttgtctc aaaatataga
    17761 taaatttatt tttcattgct aaaatgatta aaatatattt gatttaatat acttgattta
    17821 atataaaaaa aagagtgtct cataaactaa aaagttcact tttagacact cctttatata
    17881 tattatctac ttcttaattc atttattacc tctctacatt ttctttcaac tagtggatac
    17941 atctttataa gtactaatta ctccacttaa aaatgattca ggtactgtcc atcagtcata
    18001 tttttctgcc aaatataatg gtgtttcata atgagacaat aaatatttat atctctactt
    18061 atcttctcta agctcgtcaa atccaactat aggtatattt aaattatatt ctttaagtag
    18121 cttttctagc tcttctataa aaataccttt cccatccacc atttgtatat catttatttt
    18181 atccatcaat tcattgcaac cacttaactc accaaaccaa cgtttagaac tacatgtctt
    18241 attataacca caacttggac tgccatctat tgcaatgata ctttttatat cataattatt
    18301 ttttaaatat tcatcaaact gccttacatg aggtattaac atttgcctac attgttctct
    18361 aaaaaacaaa ttgtcaaact gttcttttac atgtccccac ctatttattc catacataat
    18421 catttctggg catggtagtt gaattattcc atacccttta tttattaaat ctatcgctat
    18481 attttgtgct cccttaaatt ctgacaatcc ctctacttta gaattacaat ttaatataca
    18541 atgacatact actacaatct ctctatttct cttcataata atctccttag ttattcttaa
    18601 ttttaatgat actacatatt ttgataatta tattatttat ttgttctata tttccaatat
    18661 tctatataga aatatacaat tagtaatctt ttataatcta tactatgata aatgtatata
    18721 tttttttagg aggtattata attggatact aaaaaagtca cattttcttc aatgtgcata
    18781 gttattaata ttgtcttagg tatggttata tctatgataa atataccatt attattttta
    18841 gatacagttg gtactgtact tggggctgtc gtattaggtc ctttttgggg tgctcttatt
    18901 ggtgggtgta caaacttagt tttaggtgtt atatcaggtc ctacaaatat accttttgcc
    18961 cttgtaaata ttgttcttgg tcttattgtt ggatatattt ctaagaaaaa aggttttggt
    19021 tataaagaag ctattattac aggagtaatt ttatctattg tttgtccttt aattggcact
    19081 cctatttcag ttttattgtt tggtggttta agtggaagtg gcgctgattt attggttggt
    19141 tttttagttc agtctggtca gaagatattt actgctgcgt tctttccaag gattcttagt
    19201 aatatagtag acaaaccttt gtcttgtatt atggtggtat attttataag taaaatgcct
    19261 aaaggtttta taaaacaata tagtaaaaat acttctagtt attcttagta aatttgtaca
    19321 tactatatga ttttttaaat gttataacaa gtttatacaa atatatttgt ataatatctt
    19381 tgctacttta tttttcatta attttagtat tagtgattta attatttatt atctgtatta
    19441 atttaattaa atacaacctc ttaatataaa tttagattct aaaattatat caagaggtta
    19501 tatttttatt ttataatata tttaaagttt tataacaatt tatagaatat atgtttttat
    19561 tttagctaaa atacctctct aaaaatcatt ttttacaagt atttcttata tcaacaaata
    19621 tattctcatt ttctataaac aactcataca tatcttcaaa ctctagtata ccatatccat
    19681 gagagtcatt atctcttaat tttttaagtg tttttaataa tatcttcttt attctatatt
    19741 tctaatttga cctcttaaat atacaaacta aagtaagata tctactatag acatcttact
    19801 ttagcttcat ttatgaatag gttttattat taacacttca ctatctctat tgcttttcct
    19861 acacatccac aaacttccat cctactctta acaaaatctt taactgactc taaacctttt
    19921 ttaccatatt ttttagggtc aattacctct gggtcagaat taagcacatc cttaacccca
    19981 ttgctataag caatccttaa ttcagttgca taattaacct tgcaaatccc tctttttata
    20041 gactccttaa taacctcatc tggtattcca gacccaccat gtaatactaa tggaactgat
    20101 acaacatctc taatttcaga taatctatct aaatcaagct ttggctctcc cttatataat
    20161 ccatgtgccg tacctattgc tactgccaaa gatgataccc ctgttctctc tacaaactct
    20221 tttgcttcta atgggtctgt atatgctccc ccatcaccac catctaaatc gtcttcctta
    20281 cctccaactt tacctaattc agcttcaaca ggtatatctg aaggcataca tgcatctaca
    20341 acagatttag atattgaaat attatcttca taactttcat gagaaccatc aatcataata
    20401 gaagtatatc caactctaag tgcctgcata gctagtccaa agcttgaacc atggtctaag
    20461 tgcattgcca ctggaacact tgccttctct gatgctacct ttacattcgc taaataataa
    20521 tctagtcctg catactttat tgttgaaggt gttgtttgca atattactgg tgatttaagt
    20581 tcttcagcag cctctattac tgccataacc atctccatat tttcaacatt aaatgcacct
    20641 actgcataat gcccttcttg tgcatctaat aatatttgtt tagttgtcac taatgccata
    20701 atttctcctc ctatatgttt atactgattt aatttcttcg ttatttaatt ttgatactat
    20761 ttctctactt gttttgctat ttaataactc atttaaaaat tcttcattca ttaattttga
    20821 agatagttga gataatgttt ttaagtgtaa attatcacca ttatctgtag ctgctatcat
    20881 aaatataata tgtgccaagc ttccatcttc tgattcaaag tcaaaccctt cttttgatac
    20941 acctactgct acacgtggta cctttactgc atctgttttt gcatgtggta tcgctatccc
    21001 cataccaaaa cctgtagatg atatttcttc tcttttaagg atttcttctt taaacttctt
    21061 tttatctaaa agaacaccag atttatcaag tattccaatc atttcatcaa ttacatctgt
    21121 tttatttttt cccttaacat ctaaaattac tgtttcttcg ctatataaag aaatattatt
    21181 agatacattt tccgattctg cactttcatt tttatgttca tcttttgttg catttgtatt
    21241 ttttatagta tttttctcat ttactacttt aggtgtaacc atcatataaa gtacagcacc
    21301 tactaatgaa cctacaaata tacaccctac ccataaaagt ggcttattga ctaatcctag
    21361 aaccaaaaac cctccatgtg gagctggtac ttctattttc attatataag ttaaaattga
    21421 tgatattgat gatgcaatca taagtactgg caacactttt aatggatttt ttgctgcaaa
    21481 aggtattgcc ccctctgtta tatgagtact acctagtata taattgatta atcctgctgc
    21541 tctatcttct tctgtaaatc tatttttaaa taaagtagat gctattgcta ttaccaatgg
    21601 tggtgttata caagctgcag atacacctgc cataaataaa taatttccct gtcctagaag
    21661 catagttcca gttacatatg ctgctttatt tactggacct cccatatcaa atgctgacat
    21721 acatcctatt actattccca aaattatagg gcttgaattt tgtaaccccg atagaaagtt
    21781 catcatagca ttgttaagtg ctgaacatgg cccaccaagt aacaacattg ctacacccac
    21841 aagacctacg ctgacaatag gaattataaa aatcgattta agaccttcta attgtcgtgg
    21901 taattttctt aacaaatgta caaatagttt aactaagtaa cctgctaaaa atcctgatat
    21961 gattccacct aaaaaccccg aacctgtatc aaatgatatc attcctccaa caagtcctgc
    22021 caacatacca gctcttcccg atatagattg agctataaat gctgccaata caggaaccat
    22081 caagttcata gaatatccac caacagattt taatgtagct gctatttgat tatattgttc
    22141 tgaatttggg tcaaatgaat aaatccccca taaaaatgat atagcagtaa gtactccacc
    22201 tgctactact aaaggtaaca tgtgagatac accattcatt aagtctttat acaacttttg
    22261 accaaacgat aaatttcctt cttctgcaat tttactgctt gataagtttc cttttctaat
    22321 agctactttt ccatcaatac atctttgtat aagttcatta gctttatgta taccttcttt
    22381 gacaggtact tctattactg gctttccatt gaatctgtcc atatcaacat ttttatcaca
    22441 agcaactatt attgcatctg ccatttcgat atcttttgct gttaacttat tttctacacc
    22501 tatagctcca ttcgtttcaa cttttatgtc acaccctaat tccctggctg aattttttaa
    22561 tgcttcttct gccataaaag tatgagctat tccagttgga caacctgtta cccctagaat
    22621 cattttcttt cccattttta taccaccttt ctgactctta tattttttat ataatcttcc
    22681 acattctcca aattacctat accattactt tcagccacat ttgctcctgt tgctgctgac
    22741 ctttttaatg cttcttcaat atgttctgga ttttccaacc atatacttaa aaaagcagct
    22801 aatgcagaat caccagcaca tgcagagctg actactgtaa ctggttgagc actagcataa
    22861 taaattgatt ttccattata aaaataagaa cctttttctc ctaaagttag caatatattt
    22921 tgagcacctt ttaaatgcag taatttaagt acatccttaa tatcttcttc atctcttaca
    22981 ataattccaa atatatcttt gatttcttca tcatttggtt ttatcaaata tggattatac
    23041 tgtagtaact cctttaattt tggtgaactt atatcgagta ttgtctttat acttttattt
    23101 ttacaaattt taaatatatc ctcatagtaa ttatcatcaa taccaggagg tagacttcca
    23161 cttattgata agtaacttat atctgctaat gactgtatct tatctagcat atctagtttt
    23221 tgtttttcat ttacatatga cccagagttt acaaatttaa attcatcact tccatcattt
    23281 aaaaatatat ttatacgagt tgtatcttct acccaagtag gcaatacgtc aaatcctctc
    23341 ttttcgcttt cttcaactat atattttcct gaaaatcctc caaaaaatcc taatatctta
    23401 gattctatac cataatgacc tagtacaaaa gttacattta atccctttcc attaggagaa
    23461 tatacagcat ttgatgtacg atttactaat tttctcttta tcccattagt agatatattc
    23521 atatctattg caggattcgt agttaatgta tatatcattg tcttccccct tgctcgtgct
    23581 gtgtatgttt tcattataat aaaaaagtct atgaaaatct tttcacaaat agaaaatcga
    23641 ttttcataga cttttcaatt taattttcag aattattata tctgaccata taatctataa
    23701 ttatcctaga tataatatac aagggcaatc tggaagatac ttcatattca gaaattgata
    23761 tatgttcatg tttgtatcct acaatatata aatccgaata ctttataagt tttgcacttt
    23821 cactacaaca gcaagttata accttagctc caactaaatt ggcattctgt gctgattcta
    23881 caagctctat ggtatttcca ttcaatgaaa atataattat aagttcgtct ttttttattg
    23941 atttagattt tattttcatt atgttggggt catttataaa aacaacatta aaatcaagta
    24001 attgcaattt aagactaaac tcttttgcta catattcagt aagccctctt gccaaaatat
    24061 atatcttact agatttattt atagttttta ttatattgat tagtgtagtt aaagatattt
    24121 gttctataac tctctgtgct tctataaagg atttatttat tatatccccc atattttgta
    24181 tatcatcatt ttcatctttt actgttaatc tatacctaag ttcattgaat ccatttaaac
    24241 cacattttct aattgctctt gaaacggttg ctggagatga atatgtttca tgagcaatct
    24301 ctactataga taattctggt aatattgatt cattttcatt tataaattta attatttcaa
    24361 gttccgtctt cgttagattt tcagaattac ttttgtttag ctcaattatc atatgttatc
    24421 tccccttata taagttttat ttgtctaaat ttatcgagta atataatata ttacctctta
    24481 actacttatt tttatataca attaagattt agtcaatgtc tatatatgta aatttataat
    24541 ataataattt tttgcttaaa gtttattatg ttatcttata gcattttaaa ataaaaaaga
    24601 attgtacctc taccaaaatt tggatgaagt acaatagata ttcctcatac tgatatgttt
    24661 atgattaaaa gtataaatat aaatttcgct atgaatcata taattaataa atcattttat
    24721 ttacaattat aacccccctt ataaaactat attaataata tatacagtat ttataagggg
    24781 ggttgtttat atttaaaaac tatttacttt tctcttaatt cttctccatt agttcttatt
    24841 acattttcat accaataaaa actatctttt ttataacgtt ctttacttcc atttccattg
    24901 ttatctatat ccacatatat aaatccatat cttttttcca tttcttgaga tgaacaactt
    24961 actatatcta ttggtgacca catacaataa gctaatattt cggttccatc agctatagct
    25021 tcacctattt gttctatatg ttttcctaaa taatctattc tgtaactatc atgaactttt
    25081 ccatcttcaa atttatcatg cattccaaat ccattttcag ctatcattat tggcttttgg
    25141 tatctatcat aatattgaga taaagtattg tataatcctt ttgggtcaat tgcccacccc
    25201 caaggatttg cttttaaata tggattcttt atattgtcag ttggattcat ggtgttttta
    25261 cttgctgata ctgttgtaga ataatagtat gataaagcta gaaaatccat agtattttct
    25321 tttaagattt tatcatcacc ttcctccata actatattta tgttattttc tttgaaaaat
    25381 ctcttaatat agactggata ctctccccta aaacttacat cagtgaaaaa atattgtagc
    25441 ctatttcttt ttaaagcaaa tactacattt tcagggtcac aatcttctgg ataagatgta
    25501 caatctgcca tcatcatccc tatcatcata tctgaattta tttcttttcc aagcttctta
    25561 gtcaaagctg tagctatgaa ttgatgatga atagcttgat atctagcctc ttctacatta
    25621 tctacttggt ctacacaaaa tgcaactgaa ttaaatgatt cataatgtat taaatttatt
    25681 tgatttataa ctatccaata tttaacttta tttttatatc tatttagtat taattctgca
    25741 tatctaacaa agaaatctac cacttttcta ttagaccatc ctttatattt taatactaaa
    25801 ttcaaaggag tctcatagtg aagtagtgtt acaataggtt ccataccatt atctattact
    25861 tcatttataa gattatcata aaactttaat ccctcttcat taggctctaa atcatctcca
    25921 tttggaaata ttctagccca atttattgaa aatctaaaac actttaaccc tagctctttc
    25981 aaaagcttta aatcttcttt gtatgtatga taaaagtcta ttccactacg cttaggatag
    26041 tacccatttt tatctttcat agcaaacttt attctttcta tagtcatatc agactcataa
    26101 ggtttagata tatctctatc tttatcatac atatgtacat cagctaaaca ccaacctttg
    26161 ccaccttcat tccatgcacc ttctaattga ttagctgcta cagctcctcc ccataaaaaa
    26221 cctttaggaa acttacccaa tttaatcact ccttatttta tttatttaaa tcatttacta
    26281 ttatttacct tatattctat agactttact atacctacta aagacatagt tatatttaac
    26341 tcgctgaata tggtcataag agtatcttga gcatgtgcaa ataacagcga atgtgctctt
    26401 ttctctccac cagcttcccc ttgtataatc ttggtttgag ctctatgtgc ttctgtcata
    26461 aacccttttg ctttagctag ttttaaatcg gcatttctat aatcaaactt ttccaaatca
    26521 ttaagagcat gtttaatttc tgttctagcc tcacctgcac gaagtattat ttgcattgct
    26581 acttctacta attcttcatc tattatatgt tcttcaattg tcatatttat aatttccttt
    26641 caatttctaa atttaaacct cttggctctc taattttatc tcttctttct cataagcttt
    26701 aaaaaatgga taccatatca taaatagcaa tactatattt attgctaaaa caataagccc
    26761 tctaacatct tgatttacca taaaagtaga tataccaaaa ggaacatact ataaattaaa
    26821 caccttactt ggaattgtca caaatcccat actcattgat aagtaagtag ttattgatat
    26881 tactactgtt cctatccaca taggtaacat taaaaatggg ttccatgcca ctggagctcc
    26941 aaatattact ggttcattta tattcattat agaagggaca atacatgctc ttcctattgc
    27001 ttttattctt ccaactctgg ataaacacat cattataact aatggtaatg tagcacccaa
    27061 ccctcctaaa gttatccaac ctgtttgaat aacttcgtaa acatatatat tagttgctac
    27121 tcctcctgat gctactgctg ctgcattagc tgcaattgca ccaagttgaa ttgaataagt
    27181 tataggagat agtacccacc cacttattcc taaagaatat ataaatacta ctaagaagtt
    27241 taagagtaca aatccaggta atgtctgtgc tatatctgat actggtttaa atactctaac
    27301 tattatttca aacatgtcaa agttgagtcc ataaattaat ccccagccta caaacattat
    27361 cactgttata ggtaacatat tatcaaacca cttgcttaca aaatctggaa gtgctgaatc
    27421 ttctccgaaa aatgaaaaag aaccaaataa agacattatt aatccagaga ataatcctgc
    27481 aactagcgat acaagcattc cttctcctcc aaacctgttg aagttaaata tagctccttc
    27541 attcgtaatc tctggacgaa tcatcattaa cattaatcca gcgcctgcaa gaccagctac
    27601 tacactcata ctttcaaatt tcttattctt cattatttcc ataggcaata aaaatgctat
    27661 aaataatcct aaaagtccaa atgtatattg atttattgga cttaaatcag gtaaaaagct
    27721 tatgtaattc ttcaagacag aaactatagt tactaatgag cctacaaata ccattggcaa
    27781 aactttcatt atagttgatt gaactgattg tacccatata ttcttagtca tattatttac
    27841 aacaggagta aatttttcac ttaaaaaatc tataaattta ttcataaaca ctctccccat
    27901 aaatatttta tttgtttgat attagttcta gtgcttcttc caaagccttt gcaccatcta
    27961 gtcttccata tgcagtttta gatatacatg ctactggaac gttatattca ttagcctttt
    28021 gttgaatttc ttccttcata taatctaaat gtggtcctag taataaacaa tctatttctg
    28081 ataaatactt atctatctct gactcacttc tcgcttttat atctgcttct ataccttttt
    28141 tctttgcact ctttctcata ctagttgcca taaaacctgt acttgctcct gaaccacacg
    28201 ccaaaagcac tcttatattt ttcataataa tacctccaat atttttatcc attaatttat
    28261 ttcttaatga actttttatt ttattatgtt tatattgtac ttaccaaata agttcatttc
    28321 acataaatat atttcctaat aataggaaat cagttactct taattaaaca tattaatata
    28381 gtataatgta tcttataata cgtacattca attatataat tatcatatca tccagatttt
    28441 attttaaaac tatgcgaggg aatctaatga aaacatctaa aaaagaacta tttttaaatt
    28501 tcataaaaac acaacatgat tggatagatt catctacatt ggctaattat cttaatgtct
    28561 caacgcgttc aattagaaaa tatgtaaacg aaattaattc caatggtgaa tttatattat
    28621 cctctaaaaa aggatataaa gtaaatctca ataataattt tcaaaccaag gttgatagtt
    28681 cagaaaatat atcacctgat aacaggttaa atttaatttt aaaagaactt atagttaata
    28741 gtaatggaat taatatattt gatttaagtg aagaattgtt tgttagccca gctactattg
    28801 aaggggatat agtcaaagct aataaattta taggaagtta taatttaaag ataaagcaat
    28861 cgaaattttt attgaaacta attggaaatg aatctgcaaa gcgcaagtta atgagctcta
    28921 taatatttaa agaaacggga agtgattttt taagcttatt tgatgtacaa aaaatatatc
    28981 aagagtataa tttgactaaa ctaaaagaaa atataatata tatattaaaa aaatacaatt
    29041 tatttataaa tgagtatgct ataaacaaca tacttcttca tttaatgata actatagaca
    29101 gaataaaaaa gaataattac atagactctg ttgaagtagt aaactacata gacaataacg
    29161 tagatataaa tattgcaaaa gacatatcaa attttttaga atctgaatac aatataactt
    29221 taactagtgc ggaattatac tatttagtat ttcagttaac aaacaaaact acagtcttaa
    29281 actacaatca aatggatact aaatcattgt caaattatat agatgaacac tttgttaaat
    29341 taactaaaaa aataattaaa aatgtatatg acttatatct tatagattta tctgatgagg
    29401 aatttgttgt aaaatttact cttcatgtaa aaaatttaat cagtagagcc aaaaataatc
    29461 aagttttaag aaatcaaata cctcaaaagt taaaagattc ctaccctttg atatatgata
    29521 tatctgttta tatttgcaat cagattcaaa ctttagaaaa tgtagatata gacgaagatg
    29581 aaatatctta tatatctctt catgtaggtt cattctttga tagacaaaaa ttattagaag
    29641 ataaagttct atgtgcatta attactccaa attactatga tttacaattc aaaatagtaa
    29701 gagaccttga gaagagattt aatgaatcca tagaaattat tcagattttt tcagatactc
    29761 ataatcttga ttttgacaat aaggtagaca tggttattac tactttacca attaacgata
    29821 gatgccctat accttttgtt tatgtaaatc cttacctaaa tagaaaggat tatgataata
    29881 ttcaaagtaa atttattcag attaaagata gaaaaaatat acttactgta caaaatcatt
    29941 tagaaatgta ctttagtgaa tctttgttta tgaaaaatat atatttagat agtgctaaag
    30001 attatataaa atttatggga aatattctgt acgaaaataa atatgtcaaa cccaattata
    30061 tagatgatgt tcttataaga gaaaaaatgt cttcaactgc atttaataac aatgtagcaa
    30121 ttcctcatag catgaaaatg gatgctttaa aaactggagt atgtttaatt gttaacgata
    30181 aaccagttaa atggggtgag gaaaaagttc aaattatagc tatgatacct ataaatgaaa
    30241 aagaaaaaga aaagttcaat tacatatttg aaagctttat tgaaatatta tctgagtgga
    30301 ataatgttaa agaacttact aaggcagata actatagtag ttttatgaat agaatagctt
    30361 atcttattca aaatatctaa atccgttaat ttatttccaa tatatgtttc ttaagttatt
    30421 aacataaaat agataagctg tcacactaaa aagtctaaat taatatgtga cagcttttta
    30481 cctaatatac cttgttttaa tactacatat tttttgactg ttgtatacta gttataagat
    30541 tgaatatttg tgttgttgta gctgtcatat tctcactagc agttgcttta tccattgctt
    30601 cttctattgt catagctcta tttactatag aaaaataagc atctataccc tcttcattac
    30661 atttaactgc atcttctgtt gtggctccag ccaaacctat tacttttacc ccatattttt
    30721 ttgccagttt tgcaactcct attggagcct tgcccatagc agtttgattg tccaatctac
    30781 cttcaccagt tatgacaaaa tctgcatctt ttaactcttc ctctaattta atttcttcta
    30841 atattatttt tattccagat tctaattttg aatttaaaaa tgctaaaaaa gcaaaaccta
    30901 atcctcctgc tgctcctgct ccttctacat tagctacatc tttacttaag taatttttaa
    30961 ctactttgga aaaatttcta agcccattat ctaactcctc aattatttct gatgttgcac
    31021 ctttttgaga cccgtatatg tatgcagctc catttttccc aaacagcgga ttatttacat
    31081 cacaggctat tttaaactta cattcatcta attcctttaa tctattttct atttttatat
    31141 gtcttatttc atttaaaact tttccaccta atcctactaa cttgttattt ttatcataaa
    31201 actcaaaccc taaggcttga agcataccta tcccagcatc attagtagca cttccaccta
    31261 tcccaactat aaaatttcta tagcctttat ttattgcttc ctttattatt tccccaacac
    31321 cataagttgt agtgtataaa ggatttctaa gttcagtcgg aaccaatgtt aatcctgatg
    31381 cttgagctat ttctattatt gctgtacttg tattttttaa taatccatat gttacatcca
    31441 cttttttagc tattggtcca gtaacttcta tagtctcttt tttaccattc atcccttgaa
    31501 ctaaagcatc tactgtccct tcaccaccat cagcaagtgg caatatcttt acttgcgcat
    31561 cttctttaac cttcaatatc ccctttttta ttgcatttcc tgcctctatt gaagataagc
    31621 ttcctttcaa agaatctata gaaattaata ttttcatatt tatctactcc tttttattac
    31681 tccttatttt aaacatataa ttttataagc ttaatttatc ttttatttta tactctacat
    31741 ctctctttgt atacaactta taccattaat attcttttat cttataaaaa gggagtgtct
    31801 caaaataaat ttcttagttc atgagacact ctttttgtat aaaatcaaat atatgtttat
    31861 tatttcaaca atgataagga ggattatctc tattttaaga taattccttt ttagcactat
    31921 ctaatcattt ttagcactat ttaaccaata tagttttaac ttggttcatt aagcactcta
    31981 catttacaga gttattatct attgatatag attctaattc tttttcattt aggttaatcc
    32041 atttagctat tttaatattt ttgttaaata ctatgttagc tgattttgtt tcttctttag
    32101 aattataaaa tctaactact aatgcctctt gtttttcagc cttttttaca acacttaaca
    32161 caaggtcctt attagtttcc ttaagtaaac tatatgaata atctacttct atttctgatt
    32221 gattcaattt catagcatta tatggcattt tattataagt ttgtattttt gttaaatact
    32281 ctttagccat atttgcaaca tttgcttcta gtgtagattt ttcatgagta actattgcta
    32341 agtctatttt tatatctcct atcatttgag aatctggagt aggcaacttt attcctgatg
    32401 gacgacctgg gcgtcttgcc atttcttctt tacctaggaa tcctacactt ctaaataatg
    32461 ttatagctat tgtgtcaaat ttttccccta ctatttcaaa ctctcttgta ctgtttgtaa
    32521 gaacagctac tccatgctct ttgtcagaca atccaacgaa tgttagcatt ggatatatag
    32581 aatctggtct ttcactccat tcttcttgtt gccaaacttc catagcatca tcatacacac
    32641 ttctctttat atgtccaaac tgattatcag acacagaaaa ctttgaagct atatttgttg
    32701 gtatataagt tctaacccta caatctcttg cttggttatt tatgttgaat actacatcta
    32761 ttatagcttt atcatttgga acatttataa ctatatcaaa gtcaataaat gaatctgccc
    32821 tattattttt tctagcttgt atatcttttg gtacttttaa tctataattt atctttatct
    32881 cattattaaa tctatttttc tttatagtgg aatttgctac tatattatcg ttaaatatta
    32941 atttctcatt tggaagtggt gaaaaatcat actcatctcc ttcatctcct ccattttcca
    33001 tcaataatac attttcaaaa gttttattta attttttatc aaatatcttt aatgtcccgt
    33061 tttcattaat ttgaatagta taaaagtcat tatctaccat gtcacatact tcataagctt
    33121 tttctaacat atgtccaatt tcttttatca tatacgcctt ataccccatt gcaggtattt
    33181 tatctttaaa gtttattgta tataccataa atgaatcata gtttccataa tgaacaattt
    33241 gacggtctat taatcctgca tctattactt ctttatgtac cacttcaaaa tccaacttat
    33301 tattatcttt atcaaatatt tcaaatgctt tcattttagt tataacttgg gcgttcacta
    33361 tttcattcct atcgtaaggc attaagttaa atgctactaa cttatctaaa gccatttcac
    33421 aactcattgc atcaactatt cttcttttgt aaaatgttat taattggtct actttttcct
    33481 cagctaagaa aaatctattc attatttcat ggtgaacttt atctgaacaa caacatccaa
    33541 tgctgtcatg agcatgattt ttcattattt ctttccaaat taactctatt aatccatgat
    33601 gatattcaaa tcctagagaa tatgcaatag aagctagtgg ctccaatatg ttggttatct
    33661 ttgattctat tctagcattt gctgatttta tatccattct tgttgagaat atacttctat
    33721 gaaccctcat atatttccca tctaaaaatt ccccttttat tgtatctata tcctcatttt
    33781 tttctagctc tttaaatatg ttttcatatc tacttaagaa aaattttctc tctggataac
    33841 attcttttaa tttatatata acttcaaata tattcttttg aattggcatc tggtcatgtc
    33901 catttggaag tattatatgg tcagtagttg cacccttatc aagaaccggt aaatatttat
    33961 ccattcttgt tcttagctca tcttcattca ttggtagata ttttcctatt gcataaccta
    34021 atggaagtat ttgaaccaaa acagaagacc catcatcact cttccaatta aactctgttt
    34081 tattagttcc ttttctttca gaacatcctc tccaaaacat tgagtatttt atatcaaacc
    34141 catttagtat ttgtggcatt tgagcacttt gaccaaatga atctggtaaa tatcctattt
    34201 tcatatattc tccaaattca tcacaatctt ttattccata tagtaaattt ctaagtatgg
    34261 attctccacc aactaccatt tcatcagttt gagtatacca aggacctatt attaaccttc
    34321 cttcttgaac taattttttt attctctcct tacattcagg cttaactgct aaataatctt
    34381 ctaatatagc agtttgacca tccatcacat aatatggata gttatgatta ttttctaaca
    34441 tatccattat ttcttccata ttatttacaa gtaatattct agattcctca gttgagaagt
    34501 accattctct atcccaatgc atatgaggaa ctatgtgtac attttttttc attgtttatc
    34561 ctccaaaact tatctgataa tattttctgt ctaattaaaa atccaataaa aatactactg
    34621 agtttacaaa attttttaat atttatttta tcactataat taaacctttg atttaaatat
    34681 ctaataacgt atctttttat gtatctttct ttgatttttt tgtttcctag ttattattaa
    34741 taatattgct gatattatag ctccaagtac tgccgcaaag aaccatattg atgctataat
    34801 aaatcctgac gtacttccct ctaaaagcgc caatgagaat atccccgctc caggcacttg
    34861 aagacctata ttgaagaatg ctactataga cccagttatg gctgaaccag ctaccaatga
    34921 tggtataaca cggattgggt cctctatcat aaatggtatt gcaccttcag ttattccagc
    34981 caatcctaat atccaagttt gctttcctat ttccttttct gattctgaaa ataaatctct
    35041 gcctaaaaca gtagctattg taactccaaa agctgaaacc atcttaactg atgcaaatat
    35101 tgcataaggt ataaaatttc cacttgctat tgctcctatt gcaaatgtat aggctgcttt
    35161 atttattggt ccacctaagt caaatgaaac catagctcct attattgcac ctagtagtat
    35221 tgcatttact ccagtcatcc catttaacca atttataaga ccattgttaa gtgctgctac
    35281 aggctttcct actacaaata acatcaataa acctactacc aaagaaccaa ctactggata
    35341 tacccaaaaa cttacgaatc cagctaatgt gcctttggct ggtatattct tctttaaaaa
    35401 ttttactata taaccagcaa gtaaacctcc taacatacct ccaagaaatc cactacctat
    35461 taaatcagct gctagacctg ctgcaaatcc tggtccaaga cctggttttt cagctagtga
    35521 gtaagacata tatgctgata atactggaac catcaatgta cctaacatac ctccagaaag
    35581 ctttcttaat tgccataacc aagaaccttc ttggttgtat agttcttgta gaccaaatgc
    35641 ttgagatgct aatactgcaa atgcaagtat catacctcct gccacaataa gtggtattat
    35701 atgagatact cctgtaagta ttgctgattt tacatctttt ttccatgatg atttttcaca
    35761 atatgatata tcagatgatt tttctatata atcaccttta ccttgttttt gtgctacttc
    35821 taaagcttcg tatattattt cttttgctct ttttagtgga gctgctactg acgtttttat
    35881 gtttggcaaa tgttcaaatc tttctgtatt tttaggtgct acatctgttg catatattat
    35941 tgcatctgcc ctttttatta tatctggtgt atgagggtcc accataccat tagctccttg
    36001 cttttctaca tacacatcca caccgatttc tttaccagct ttaattaatg cttctgctga
    36061 catatatgta tgtgctatac ctgcagggca tgctgttatt gctaatacaa ttttttttga
    36121 ttcattttga atcctaatct cttcttttat ttgttctttc ttttctttta tatctaagtt
    36181 attaaataac tctttcttag tttttgaatt taacaacata ttcatataat cttcatttga
    36241 cagtctagta actaactcag aaagtatttg tatgtgtgta tttccacctt tattttctgg
    36301 tactgctatt aaaaatatta gctctacttt attatttggg tctacgcttt cccaattttc
    36361 tattggtgtc tctaaggtca tagctgcaaa tgaagcttct ttaactgact tagattttcc
    36421 atgaggaatt gcaagccctc tttcaaaacc tgttggagat aaagtttctc tgtacattac
    36481 agcttctaaa tattcctcat aagatgttaa cttgccttca tcatatagct ttcttgctaa
    36541 gaactttatt gcgtctttct ttgtttttat tttttgtttt aaaaaaacaa ggttttcatt
    36601 tgtgattttc ttaaattcca aaattacgcc ctccttaaat aatttaatgc tatgaatata
    36661 gcataaaata aattatgaaa atgttttttt gaaattatac acacaatttc ttcttaaaaa
    36721 ataaagattt gtgtatttat acacaaatct ctatcttaac cagtattgct ctattattgc
    36781 tctcataatc atcataattg gaaccttatc tgatatattg tacccattta cttgtttaat
    36841 tgttgaatag caatataaac ttatatctgc aatttgttgc aattgatttt cacatatatg
    36901 tgttagagct actaccttac aacccttatt aactgctgtc tttgctgctt ctataacttc
    36961 tttcgtttct ccacttaaac taagtgcaaa aaacatatct tgttcaccta attttcctat
    37021 atcatgaagt acttcatgtc tttgactata gtaagttata ttatcatgcc cacctctaat
    37081 ttcttttact aatatctcac ataaaggaat gttttgacct attccataaa ctataatact
    37141 cctagatttt tgaattatat ctgctacttt atttattttt tcataatcta ttagctctaa
    37201 tgtctttttt atatctgatt caaaaccatt ttttggctct ttatcctcat tttttaactc
    37261 ttcttttaaa ttatttttta gttgagagaa accatcatac tccatttttt tacatagcct
    37321 aactatggta tttgggacag taaaaaattt atctgctaaa gattgtattg ataattttac
    37381 tatttcttct ttgttttttc tcatatattc aattatcatg tcttctgtat ctgtaaattt
    37441 atactcatat ttttttgctc tttcataaaa ttccatagtt tctcctccat ctattttatt
    37501 attcataagt aaaattcaaa aatattagct aaaattttcg ttaatataat tataatttaa
    37561 tatttttaat ttattaatgc atactactct ttttattata cataaaaaat gtgtacttcc
    37621 tatattgata gagattattc aagtttttat tttgatacat ctctatcaat atttttttag
    37681 aaaatacaca tttttttcaa atacttattt ttaattaaaa ctttaggtaa tctattcttt
    37741 atatataatt attagacttg aaaatatctt taaaatcaac caattcaata ttatttcttt
    37801 ttaaccatat tttaacttcc ttatcacata gcattgcatg ttcatatact ctttcttgaa
    37861 taagagaaga tgattttata agactataat ctataaatcc tggatgagta accatcaatg
    37921 ttatatcttt atctaaattt atatattttt cttcaaataa tttaacaaaa gatttattta
    37981 acttgtaaaa atcattctga ggatatttac ttggcatgct aatacatgaa tctaaataat
    38041 agggacaact tggtataccg tattcttttg cagcatcaca cattgctgat attgatacat
    38101 cttcttctat accatgtata tcaatatact caggcaattt actcatatac aacttgtaag
    38161 tttcaatttg agcacaaact tcttcatata cttcttcata attaaaaacc tctttacctg
    38221 tcagtagttg cgttcttctt attttgctag aaacaaattt tccaccttca tctaacaaat
    38281 tctttatctt aatatgttct ttgcaacaag gttctcctat tactaaatta acatgtaaac
    38341 caaaacatac atcatcattt tttaccattt ctatagcttg tcttgaaaaa ggcatattca
    38401 ccatgattcc agcacttgta acaataccgt tcttataaga agatattatc cctagtgtaa
    38461 caccttctga atatcctata tcatctgccc taactactag tttcttcatt ttatgcgtct
    38521 gcctgctttc tcaactcatc aagttgcatt tccatctcat cctttacttt aacaacatcc
    38581 gttcctatga tgatttgaac tgatgtatta ctcaatttaa ttaccccttt ggctcctgtt
    38641 tttttaatat tatcatcatt caaaatagta gcatccttca cttctaaacg taatctcgtc
    38701 atacaattat taagagtcac tatattttca taaccaccac aatttttaat tatctgttta
    38761 gccatatatg aaaaattacc atgagaaagt tttaaattct tttctttttc actaacttta
    38821 tcacctatct ctatctcaac ttcacgtcct ggtgtttgca cattatcttt tattattata
    38881 tatttaaatg ttacataata taatacaaag aacacaactc ctacaggtat aactaaccac
    38941 gctttatctc cataactaaa acttaagaca tagtcaatta tacttgctcc attaaatgaa
    39001 cccaagcgag cacccagtaa atatagtaca actccaccta gaccagaata aaaagaatga
    39061 attatatata actttggaga tgcaaataaa aacgaaaatt ctattggttc agttactgtt
    39121 gccataaaag aagtcaatgc tccagcggtc attgcacctt ttacttcttg cttcttttta
    39181 tcttgtgctg ttttatatat agcataagaa atagcaggta ttgaaaacat cataattatg
    39241 taaaatcctg tccagaagaa tcctgcattt gggtctcctg ccataaatct aggaatttct
    39301 cctcttataa cttctcctgt tgatgttgta tattcaccca tttcaaataa tatgtaagca
    39361 tttaaaactt gatgtaaccc agttggtatt agtgcacggt tacagaataa aaacaagaat
    39421 attcctattg caccagctcc tcccaaccaa aaaccaaatt gattcattgc agcttgtgga
    39481 tatatccata ataaactaaa tatatatgat aaaattaaag caaccactgg tgatagtgta
    39541 attacacatt tttctcctgc aaagaagctt aaaaatgctg gaactttaac tttatatgtt
    39601 ttattgtaag tccatgctat acaagctcca acaattatcc caccaaatac acctgcattt
    39661 aatgtatcat tcaataactc taaatttgac ttaaatatca tatatgcaac tacggctgca
    39721 accattacac ttgtcttgtc tttagacttt gagtaggcac tagctgctcc taataaaaat
    39781 aagtagtcca catttgaaaa tactatatta gatatattag atatagctgg cacattgagc
    39841 atatttggac caaataataa tcctaatata cctgctgctg gcattacagc tattggcacc
    39901 agcatagtct ttcctaaaag tgacagttgt tgcatcattt tgtttaagaa cctcttcata
    39961 tacaatcccc tttctatttc ggtttaattt tttgtgaaaa cgatttattc acattttata
    40021 ttttaaatat tatatttgtt taaacaaatt gtcaatattt tttattcatt ttatttttat
    40081 catttagttt aacatataaa tccttttaag tgtattgcta tatctagcct atttttttaa
    40141 ttcatttttt ttattttaaa aatatgttta accatatatt tgaaacaacc cacaaaataa
    40201 ttctattttg tcctttttat ggttgatatg attctatttt cactatacat gtctaaacac
    40261 atttgatata atttgttcat atcagttcaa taatattact aaagaccttt aaggagggat
    40321 aggggtatat ggctaaaaat aaattttcag agatatatga agtattgaaa gaggaaatac
    40381 ttgatggtaa atatacaagt aatatgatgc tgcctactga acttcaactt attgaaaggt
    40441 tttcatgtag cagaaacact gtacgtagag caatttctca attaaacaca gaaggatatg
    40501 ttcaaagtat aaaaggcaag ggtgttgtag tgttagaaaa tagttgttct aatgattttt
    40561 ttctaaatat gcacaatttc aaaggtgtag aatcgattgt agaagataaa aaggttaata
    40621 ctgctactag tgttctccac ttcagcaaaa tcttaattga taataagtta tctaaaaaga
    40681 caggttttaa agttggtagt gaagtatatt accttcacag actaagatat attgataaca
    40741 tacctaaaat tctcgacatt aactattttc tatgtagtat agttaaagac cttgatgttt
    40801 ctatagcaca aggctctatt tataaatata tagaagagtg tctaggtaca aaaattgttt
    40861 catccagaaa gatatttaaa attgaaaaag ctacagagct tgagttaaaa acgctacctc
    40921 taaatgatta taattgtgtt ggtgttatta aaaatagtgt atatactgat gatggaaagc
    40981 tttttgaata tactgaatca aagcatacac ctgaaacatt tgtattcatg gatgttactc
    41041 aaagatatta aaaaaattat gtttaattaa acataatttt tttacgttta gacactttat
    41101 cccatactaa cctcactatt ctatatacaa ttatatgttt atacaaataa ttatttattg
    41161 tatattttag ctttaatatt agtttaacgc ttgacaattt gtttaaacat attataatta
    41221 acttataaat tacaggaggt atcaattatg aaaaattggt ggaaaaaagc aactgtctat
    41281 caaatatatc caaaaagttt caaagatagc aacaatgatg gtataggtga tataaatggt
    41341 attatagaaa aattagatta tctgtattct ttaggtgttg atttattatg gttgactcct
    41401 atgtacgttt ctcctcaaag agataatgga tatgatatag aagattatta taatatagac
    41461 ccaaaatatg ggacaatgaa tgactttgaa aaactcttaa aagaagctca taaaagagac
    41521 ataaaaataa tgatggatat ggtcctaaac catacatcta ctgaacataa atggtttaaa
    41581 gaatctaaaa aaagcaaaga caatccatat cgtgattatt atttctggaa agatgctaaa
    41641 cctgatggtt ctgttcctaa taactggata tccagattta gtggaactgc ttggaaatat
    41701 gatgaaacca ctaaccaata ttatttacat ttatttgaag aaactcaagc tgatttaaat
    41761 tgggaaaatg aaaaggttcg tgaagaatgt tacaaaatac tagaattttg ggctgataaa
    41821 ggtattgatg gttttcgttt agatgtagtc aacctactct ccaaaacacc tggattacct
    41881 gatgacccta taacaggacc aaaaggagat ggaagaactc actacgctga tggtcctcgt
    41941 atacacgaat atttacataa tatgaatcaa aaagttttca aacctaaaaa tatagttact
    42001 gtaggtgaaa tgtcatctac tacacctgaa gagtgtatca actatactag agaaaatcga
    42061 gaagaactat ctatggtttt tagcttccat catatgaaaa cagattataa aggaggcgca
    42121 aaatggacta atgaaatgtt ctctctggat aaattaaaaa aagcacaatc tgactttcaa
    42181 tataaaatgt atgaaggaaa gggatggaat gctctatttt actctaatca cgaccaacct
    42241 agagctttat ctcgatttgg agatgataga ttttttcgtc aagaaagtgc taagatgtta
    42301 gccataacat tatttggtct acagggtact acatacatat atcaaggtga agaaataggt
    42361 atgacaaatg cctactttac taaaatagat gaatatgatg atgctgaaag taagaatgca
    42421 tactatcata tgattaaatc tggtattgat gaaaaggagg cattgcttat acttcaacaa
    42481 aaatccagag ataatgcccg tactcctatg caatgggata atactattta taaggggttt
    42541 tctaatcata aaccgtggtt aaaggttaat aatgacaata ttagtgtaga aaatgagctt
    42601 aatgattctc gttcagtatt ttatacttat caaagattaa tcaaatatcg taaacaatat
    42661 gatattttta cagaaggtac ttatagattg ttagatgaaa atcataaaaa tctatttgtt
    42721 tatgaaagag agtataaaaa ccaaaatctt cttgttataa gtaattttac tcatgataat
    42781 gtagtatata aattacctga aacttatttg aataaattaa actacacaat acttgaaacc
    42841 aattacacta gagatataat tgaaaataaa atggaaataa aaccttacga aagtataatg
    42901 atatattata aataaagtta tttatgtaaa aatcggtata acaccctggt gttataccaa
    42961 ttttactaaa ttcaaagtaa tatttataga atatctatag attagaataa ttatttgacg
    43021 tctacatcat tatatttctt tgaatatact ttagtcatat agaaatatat aggaactaca
    43081 attatcatcc cacctaatcc ccaaactatc ttcataggtt catcaatacc tgcttttatc
    43141 agtaataata tacttataat aactgcaaat attggtataa ttgctcctcc aggtattcta
    43201 aaatttacat ctttatcagc atacttcttt ctcaatatta gtacagctaa acatgtagga
    43261 atatattgaa taaatctaga tacaacactt atttgagata atgttgtgaa tgaacccgac
    43321 catgctatta gtaaagttcc tatgacagat actataattg ctatataagg agctccattt
    43381 ttattagttt ttcttataga cttaggcatt aatccttgtt caaccaaagc agcagcagac
    43441 cttggtgtaa atatggatga tgcaatattt atacctccaa cagatactat agttcctatt
    43501 gtaattatat acccacctat aggacctaac atcttaatgg cagcatctgc aacaggagta
    43561 gctgaccctg ccaagccatt acccaacact cctatactta ttcccagtat aagcatatat
    43621 attactgata ctacaaacat taccattacc aatgctttag gtacattttt cttagggttc
    43681 tccatatctt ttgctgcaac agctaaagat tcaaatcctg taaaagcata aaataaagtt
    43741 atagatactg ctacaaaagc tgatgacgca ctttgacctt tttgtattat tacaaatggg
    43801 gtaaaattag aaccctttat aaagaataat cctacagcta taaataaaac tattggtaat
    43861 aattttccta tagtcatgat attatttaag tgcttagatt gtttcattcc cataaaattt
    43921 ataatcccaa gtcctacaac taatatacca attattatat ttttagtaag tggttctgct
    43981 gcttgtggcc atacagatga tagtgttaca gcaaagaaat ttgccatagt agcccaagca
    44041 atcatactaa ctatccactt cataaatcca acttcaaatc caacaaaatc tccaaatgcc
    44101 tcttttgcat aaagataggg ccctccatca gtatcaaacc aactacctgc ttcagcaaaa
    44161 cataaagcaa tagaaacagc taaaagcata caaaaaacta atactaatat acttgctgga
    44221 cctatatctg tataagcatc accaggtaac ccgaatatac ctgaccctat tattgcattg
    44281 attcctaata gtacaatact ccaaaaacct aacttaatgc ctttttccat tgttattccc
    44341 cccaaagcca acttaatata tttatatttt ttatttagat gcttctttaa ctattgccat
    44401 aaatattttt ttcatattat cataatctct agtcatcatt tctggatgcc attgtatccc
    44461 tattacaaac tcacttcctt ccttttctat agcttcaatt aaaccgtctt tagatgtagc
    44521 tgaaacaata tatcccggtg ctactttgtt gacaactaag tgatgaaaac tattaactaa
    44581 aacttctttt tctcctaata tttcatataa ttttgtcccc tcctttatct gtactgtatg
    44641 tgtaggtaca ttagatagat gttgctgatt gtgtttaata taagcacctt caattaaaga
    44701 taaatcttga tacaaactac ctccttcagt tacatttata atttgttctc ctctacatat
    44761 ccctaaaact ggttttttca tatctaaagc atgttttaat aatttcatat caaaactatc
    44821 tctctttggt gatattgccc ccaacttatt atgaggttct tctttccata tgagtggatt
    44881 tacatcttgt cccccagata gtataagcgc atctatatta gatacctgct cctttataat
    44941 ctcatcatca tatacaatcg gtacaatata tggtatagct ttacacataa ctactgattg
    45001 tatataatca ttatttacat aagccctttc atagccagga aacattcctc cttcatcaat
    45061 tagtaaatta cctgatattc ctattattgg atatttcttt ttagccaatt tcttcacccc
    45121 ttaacttatt tgtgaacaat aaaaaatgct acttctctta aagagcaagt agcataccaa
    45181 gattttattt atttgaacat tataatttat tttagaaata ctttttttga atacgagtaa
    45241 tataaataac tttatttact tatattttat tttaatcctg tttagtttga cttttttaaa
    45301 ttgttttaag tacaactaat aggtaaaata ggcatttaga ttttcctttt tatcaaccta
    45361 ttaaatactg tttaatatat tttttcccct tctatttaat tcacttccct ttctaccaga
    45421 ttcacatatt atcaaatcca gctcttttaa catattaagt attcccctta cctcaccttc
    45481 tgttatattg tagcctaatc catttattga attaacaata ccatttctac ctatattttt
    45541 attaagatta ttggcatttt ttaaacactc cattactaac tttactttct ctatagatgt
    45601 tctatccttt aatatgctta tttctttact aaaatcttca gttatattta ataagttatg
    45661 aggtaaatca tttattaaaa taacatcctc agaactcata atgttaatat acatagcagt
    45721 attttttaat tctcttatat tacctggcca ttcatatgca ttaataatgt cttgaacatc
    45781 ttgactaatt gctctcttcc ttttcataaa atgccttaac ataacttcta tatcttcttt
    45841 tcgctctctt aaaggtggta tatttatggg caatacattt atcctatagt ataaatctgc
    45901 tctaaatcta tctcctttta tcatttctaa taaattttta tttgtagccg caattactct
    45961 aacatctata tctattacat tttctcctcc aaccctcatt acttgattct cttgtaatac
    46021 tctaagtaat ttgctttgta agtatatagg catgtctcct atttcatcca aaaatatagt
    46081 tccattgtta gcctgttcaa ataatccttt tttacctcct tttaaagctc ctgtaaaagc
    46141 accttcttca tatccaaaaa gttcactttc aagtaaattt tctggcatag ctgcacagtt
    46201 tattgctata aatggctgac tatgtcttgg tgatgcatta tgaatagact gagccatgag
    46261 ttcttttccc gttccacttt ctcccgttat aagaattgta taatcagatt cagctatttt
    46321 catacctaat ttcttagttc tttccatctt cgttgaaact gtttttatat catcaaaagt
    46381 atatctagca acttgtccct tttctctaag cttctttgat aggttttgct ccaattttct
    46441 tatgtaagtt atttcttgaa tacaaaaata atatccagta acccttccaa aactctctat
    46501 attatactta tttacgttta agtacttatt attaaatttt ataacttcat catgtgcctt
    46561 actcaaacta aaaatctttt taatattctc attctctaat tcatctatat ttttccctat
    46621 aatattactt tgaatatcta gtatatcccc taaactatta ttgcaaataa ttatgtttcc
    46681 cttatctgat accattgcca tacctaagtt tgataaattt attatagaat ttagttcatc
    46741 tgcttttata gtaagttctt tgtatttagt atttattcct gaatataaac taattatttc
    46801 atctgtatac ttaattagcc tctcagtaat ttctttatca tccagtttga gttttgctat
    46861 tatttgaata aacgttgaac tatcaatata cctatggcct aaatcaataa cttcttctat
    46921 atattttgga actaaacttg actctcctgg cgttatagct atcttaatat ttctatattc
    46981 ttcattggga ttgtatggta taaaattcag atgatttatt cctatattgt ataaattaga
    47041 tattgtttcc aatacagtat gcttattatc gtttactact aatacatcta ttccttctgg
    47101 caatgaaaat aacttatata tatccttttg ctttatgctc ctatttatag ttattatctt
    47161 tgagacatct tctacatatt tttttatttt taatactcta tcatctatca ttaccaatat
    47221 tatgtcatct tttattaatt ccttctctgt tattttattt aaataataat tttttatcat
    47281 tactttatct ttaaatatca tttctagatt tttatttaag aaacattcta atttagacaa
    47341 cccatcagtt actactgcta ttgttttcat ttgattactc cttttaaaat atactctact
    47401 cttttataat atacatctga ttttcacttt aatagcacaa aaaattgtac atttagtata
    47461 ctaacatatt cctttattag ttttatgtcc ctaaatatca tagttgcaat atctatcata
    47521 tttcttaaac ttctataaag caaaaattgt gccaaattaa taattttctt aattttattc
    47581 taaagttcct caatagtatt tacagactta gcacttatag cttataagtc tttatattat
    47641 taatctattt ttataggtta attgtacaaa tcatatatca cttttaccca ttaaatgcat
    47701 tataaaaaag atggaataac gattcgtcac tccacctttt ttgtaataaa aaattgtata
    47761 tataaacact atttactact cttctaagta caaacagtat ctacatacta taacctttca
    47821 ccattagatt ctattacttg tttataccag tcaaaactct ttttcttaat cctagacaag
    47881 tctccacttc catcatcata cttatccacg tatataaacc catatctctt ggccatctca
    47941 ccagtagatg cacttactaa atctatacat ccccatggag tatatccaaa taaatcaaca
    48001 ccatcttcta cagcttcctt catttgctct atatgtgctt ttaaatactc tatacgatag
    48061 tcatcattta tcactccatt agattctttt ttatcataag ctcctaaacc attttcaact
    48121 accatcatag gtattctata tctatcataa atttcattta gtgcatatct aagcccttca
    48181 gggtctattt gccatcccca ttcactagac ttaagatatg gatttttcac tccacctaat
    48241 atgttgccac ttgtattatc ttctttagaa tcactactta cacatgtaga catataataa
    48301 ctaaatgtat aaaaatctac acaaccttct tttaaaattt ctaaatctcc tttttccatt
    48361 tttatttcaa tattattttc tccaaaatat ctattcatat aagttggata ttcgccacgc
    48421 acttgtacat ctccacagaa ataattcatt actctactat ctctttgagt tttaactgca
    48481 tcatctggat tacaagtata aggatacatt gttgcaaata tttgcataca tccaacttga
    48541 taatttgaat ctatttcatg agctaactta acagccttag cacttgctac aaattgatga
    48601 tgtaaccctt gaaaacgaag ttgaggtata tctacttggt ttataaaatc tgtagtccct
    48661 tcatttaata ttccttgtga taagtagcct cccataggca ttgtagctga atttatttca
    48721 ttaaatgtca gccaatattt tacttttcct ttatatcttt taaatattgt ttcacagtaa
    48781 ttcatataca agtctattac atctcttgaa acccatccat tgtatttctc tgttattgca
    48841 aatggtattt catagtgaga tattgttatt aatggttcta tattatattt taaacattca
    48901 tctatcacat tttcataaaa tttaagtcct gcttcatttg gttctttctc cattccagtt
    48961 ggaaatattc tagtccatgc tattgaaaat ctaaatacct taaatcccat ttctgcaaat
    49021 aaagctatat cttctttgta tctgtgataa aaatctattg cttcatgact tggataaaat
    49081 gttccttttt ctataactct cgttattctt ttacttactt tttgagaacc tccagtacac
    49141 atatctgaac aagaaggacc tttcccatct aaattccatg ctccttcaca ttgatttgct
    49201 gctgttgctc caccccataa aaaatctttt ttaaatgaca tacctatatc ctcctattat
    49261 aattcttcac catttgattc tattactttt ttataccagg caaaactctt ctttttactg
    49321 cgttttaaag ttccatttcc atcattatct ttatccacat atataaatcc atagcgcttc
    49381 ttcatttctc cagtacttgc acttactaag tcaatacatc cccatggtgt gtacccccat
    49441 aaatcaacac catctaactc aacagcatct atcatggctt ttatatgagc acgtaaataa
    49501 tcaattctat aatcatcatt tatatttcca ttttcatctg gattatctac tgctcctagt
    49561 ccattttcaa ctataaataa tggtttttga taacggtcat ataaagagtt catagttatt
    49621 ctaagcccta atgggtctat ttgccatccc cactcacttg catctagata tggattttta
    49681 agacttgcaa aaacatttcc ttctgttaaa atatttactt ttgggtctgc acttgtaagt
    49741 cttgatgagt aatatgagaa cgaaataaaa tctactgtgt tctctttaag tatcttttta
    49801 tcatcttctt ccatcactat atttattcct tttctctcca attcttttaa tgcatatgtt
    49861 ggatattctc cacgagattg tacatctata aaaaagtaat tttccctatc tttttctata
    49921 gatttccata catctagtgg gttacaagta ttaggataag tatttcctgc tgctaacata
    49981 caccctattt taaattcttg atttatgtta tgtgctagtt tagtaactaa cgcactcgca
    50041 actaattgat gatgtgcagc ttggtatttt atttgttctt cattttctcc ctcttcaata
    50101 tagagacctg cacctataaa tggtaaatga agtatcatgt ttatttcatt aaatgttagc
    50161 caatacttta ccttaccttt aaaccttgta aaaataactt cacagtattt tacatataag
    50221 tctactagct tacgatttct ccatgctcca tattttttta ccaaatacat gggaacatca
    50281 aaatgacaga ttgttactac tggttctatt ccatacttta aacactcatc aaataaatct
    50341 tcatagaatt ttagtccctc ttcgtttgga acatcctcaa ctcctgttgg aaatatccta
    50401 gtccatgcta ttgacatacg atagcattta aatcccatct cagcaaataa ttttatatct
    50461 tctttataat tgtgatacat atctattgct tcatgagctg ggtaatagtg ttcatcatca
    50521 cattcaaaca ttttcatttt cccagccaaa actggaaatc tatcttttcc ttgtggtgta
    50581 acgtcaacat tagctagacc tctaccatct tctttatatc caccttcaca ttgatttgct
    50641 gctgttgctc caccccataa aaaatctttt ctaagtgcca taattctacc tccaataatt
    50701 tatttatagt aactttattt taaaataaaa atacatatat ataattctta attaatagaa
    50761 ctctctttta cgctaaaaca gttatcaatt cctgactatt atttacatgc ttttgtgtat
    50821 tttctacaat atccacataa tcagaataat tagtaacaac tactggtgtt tctaagcaat
    50881 atccttcttt tgaaatactt tctatgtcaa aagttattaa tatctgacct tttttaatct
    50941 tatccccttg attaacaaaa gatttgaaat atttaccttc caactgaata gtatttaacc
    51001 ctatatgtat caatagttca caaccattat cagatataat tcctattgca tgttttgttg
    51061 gaaataaagt cattacagtc ccatcaaatg gtgccactac ttttccttct ttaggtgtta
    51121 ttgctacacc ttttcccaat atacctgttg aaaacgctgc atcttgtatc tgctccaaag
    51181 cctttacttc accttttatt gggctatata ctacttctct tttgtttttt tctataacgc
    51241 cttgcccatt atcatcttta gaaatttcta ctatagcatc atctttccaa aaaaataatg
    51301 ttaaaacaaa tcctactaca atagctacta ttattgctat tatagttgca taaacacctt
    51361 tcatatctcc agttgttgga tttatataat taggtatacc aaatattcca agtccaccca
    51421 ttacataact ttttacattc attatcccca ttacagctcc tgccacacca ccacctacac
    51481 agctatatat gaatggtgtt tttcttggta aagttattcc atatattgca ggctctgtta
    51541 caccacatat ccctgaaata actgcaggta tacacagctc ttttatcttc ttatctttta
    51601 atttaaagta cattgctgct actactgctg tttgtgcaaa agatggcaca aatgctccca
    51661 ctaatattgt gtcaaacccc atagtcataa ggtttgacat agctattggt actaatcccc
    51721 aatgtagacc aaatattaca agcacttgcc acaataaacc agttaatgca ccacataaaa
    51781 ttggtgaaaa gttaaataaa gctaaaaatc catttccaac tatattagaa gcataggtag
    51841 ctataggccc tataaccata aatcccaatg gtaaagaaac taataaaact gccattggta
    51901 caaagaaatt ctttactaca tctggtatta ttttagcaaa cactttctcc aacttagctg
    51961 ctaataatac tattaaaatt actggtacta ctgttgaagt gtagttcatt gctattactg
    52021 gtaatcctaa gaaagttata tatactggtg attcaaatat tgttccagta aatagattgt
    52081 ataaaggttg acctgtagat gctagagtat ctaattgaat acctgaatag cataaaactg
    52141 cacctataag cattccaata aatggtttta atttaaattt cttagcagct gtatatccaa
    52201 gaattattgg catatactgg aacattgcat ctccaattgc atttaacata atatatgcac
    52261 catcagtttc tccatacaaa cccaatgctg taaatactgc attaaatcct tttatcatac
    52321 cagcagcaca cagaactcct aatattggtt gaaaaactcc tgatattatg tctataaact
    52381 tattaagtaa tccttttggc gcatctgagt ctgaattatc tattgtatct cctcctaatc
    52441 cagccaaatc gcacacaact tcataaacat ctggaacatg attaccaata actacttggt
    52501 attgacctgc acttttcatt acagtaacta taccatccat tttttttagc acatcatcat
    52561 ttgctattga ctcatctttt aatttaaaac gtagcctcgt tatacagtga gataaactgc
    52621 taatattatc ctttcctcct acattcgcaa tgatttcttt tgatagttgt tcatactttc
    52681 tcattttttc tcctccattt tctttttgaa atatgaaggt ttggccaact taatgtcacc
    52741 acccaatata tataaaccta attattagga tttatatctg acttaatact tttacttacc
    52801 actctttcaa cgtgaatagt taagtataat ttttcctcat ctgttaaatc gtagttgtat
    52861 tttttatgta taaattcatc caacttttct atgaatttat aagcattttt atatttaact
    52921 tttattacat ttaataaatc atcttcatta ttttcatgta aattattact aacaattcgt
    52981 tctgcaaaat actttaagtg agtaataaat ctatgataat aaactgaatc ttcatcaaat
    53041 actattctgt aatggtattt aaccatattt gaaatttctt gtattatttg tgtaatctca
    53101 tatatagttt ttatactttg atccatttgt gcattaacta tatgcagtgc tataaatcca
    53161 gcttcatctt ctgatagtct aatttcaaat tttttttcta tataatccaa tgcctctaac
    53221 cctattttaa attcactctt ataaaatctt tttatatccc aaagtaatac attttttaca
    53281 cttactcctt cacgagctct ttctattgca gtatacatat ggtctgttaa agaaatataa
    53341 atactatcat ttaatctttt ccctagtttt tctttagcat ataaaattat ttcatctgat
    53401 aattccatat atcttatagg aatatctgct attagttctt taaatttatc agatatattt
    53461 gggtctgaaa gtttgaatat cttatcaatt ttatcctttg atatatgctc tcctgtacgt
    53521 tttttataag ctaaacctct ccccataact actatttcct tatgattttc atcagttgta
    53581 ataattacat tattattgag tattttttca ataatcattg tgatgccccc tttattagca
    53641 ttaagttaaa ataaatcttt tttaattatt tagaatattt aaaatgtaat ttattacata
    53701 aaaaaaaacc tatttattac acattaaata gactcccatg agtcctgagt aataaatagg
    53761 tttagcttgt atttaaacaa tcactatccg tttgtatttt attttaatta ttatttatta
    53821 tatgttagca aatttatttt ttagtgtcaa ctttttctca atattttaat tttaaataaa
    53881 ttatataaat tgaatcttca aagtactatt tttatcaata aacaaaataa aaaaggtatt
    53941 actttcttta agtaataccc atttattttt aatttaagtg gtttttctta atctcatcaa
    54001 gtagtccatc ttctaaataa atttctaatg cacatcctac cattgccttt actgctttgt
    54061 gaagtttatc ataagcttcc tcagaatttg cataatttag aaattctttt tcatgaacat
    54121 ataccattgg acttatatct aaggctattt ctgtatacat agtagggcaa acttgactta
    54181 cattacctat atctgtagaa cctactggac catctttacc ttctaatata tctgttatac
    54241 ctgcctcaat caaattattc tttgttatct tttgaagtac tttgttattt attatgttgt
    54301 caaaagaatt ttcaaagtat ctataagaaa gcttagctcc tgtcattaac tctgcacctt
    54361 ttgcacagtt tataactttt ttagttactt catctaaata acttctttca gcagctctta
    54421 cgaaaaactt acaggctgct ttttctggaa ctatatttgg agcctctcct ccatttgaaa
    54481 ctataccatg tattctaaca tctgatttta catgttgtct tagtgcattt atcccagcaa
    54541 aagtaagttg tactgcatct agtgcattga ctcccatatg agggtgacta gctgcatgtg
    54601 ctgatacccc ttcaaaacta aactctaatg aatctatcgc caaagcctta cagtttatat
    54661 tattaaaagc ttctatatgc atttgataac ttacatcaac atcatcaaaa gctcctgcct
    54721 taactaaatc acattttcct cctgttgttt cttcagctgg tgttcctatt agtacaattt
    54781 ttcctttaaa attttctttt aacttactta atactataca agctcctagt gtagatgctg
    54841 caatccagtt atgtccacaa gcatgagctg gttctttatt ttctccatat ccaggaagtg
    54901 catcatactc agctaaaaat gctatggtag gtccatcatt atctcctaat tcagctctaa
    54961 aagcagtctc catattacaa tatggataaa ctgtatcaaa tccatattcc ttcatttttt
    55021 ctactaagta ttttgatgat atgtattctt cttcccctaa ttcaggattg ttaaatataa
    55081 aattacaaac ttcttcaatt tcttttccaa gttcattctc tatctcataa gctctcttct
    55141 ttatactctc tatcataatt tacctcctac tagaatccta gatataatcc tattgtcaaa
    55201 aatgccatta caagaattgt taatactacc attaaaggaa ttacgaatct aacccacttt
    55261 gaccaaggaa tattggctac tgctagtgct cccattaaaa cacctgatgt aggtgttatc
    55321 aagttagtca cacctatacc aaattgataa gctgtaacta tcatttgtct tgatacatct
    55381 actaagtcgc caagtggtgc aagtacaggt attgtaagtg atgcaagccc tgatgctgat
    55441 ggtattaaaa atgctattaa tccttctatt aagaaagtta aatttataaa tatagttttt
    55501 ggtaatccat ttaataaatt tgctgcagaa tttaaaattg tatctattat aaatccattt
    55561 tctgctatta ttacgattcc acgtgcaaat gctatacaca atcctgctgt cattaaatct
    55621 cctgctccac ttataaatga attaactata tcatcttgtt taagacctga tgctatacct
    55681 gatattatac ctatagctgt aaatatcatt gcaatttcag ttatatacca tcccaacttt
    55741 aaaactccat atatcataat cgccatacct attgtgaaaa ttgctattac catggcttct
    55801 ctttttgtaa attcctttat atttgtatca ctattaacca ttgattcttg atttagtgat
    55861 atatcgtgta ctaaagattt tttagggtct tttttaactt tattggcata catcataaca
    55921 aatcctatag atatagccat atatattata aacataacta ctctaaactc tattccagag
    55981 cctggtgcta tttgtgataa tgcttgtgct attcctacag agaaaggatt cgtagtagct
    56041 gctccaaatc cagctgttgc tcctataaat actgtggcca ctgctgtcaa tgaatcatat
    56101 cccatactgg tcataagtgg aataaatatc atataaaaag gtagtgtctc ttcactcatt
    56161 ccaaacgtcg tcccacctag tccaaataga atcattgaaa tcggtattat taaaaattga
    56221 aacttcttca ttttatttac agtatgagct ataacagctt ctatagctcc tgttttatta
    56281 actatcccaa aagctcctcc aactattaaa acaaatccaa ctacttcagc tgcatctata
    56341 aacccgttta taggtgctgt aaatacatca gtaattcctt gtggatttga tggtgctttt
    56401 tcataagttc cagctacaac aactgacctt ccgtctatat ctactctttc aaaatttcca
    56461 cttggcacta tccaagtaag aattgccatt aacactatta gcaaaaatat tattgtaagt
    56521 gtctgtggca tagtaaactt tttctttttt aaactgctca tttttaatct ccccactttt
    56581 taaattaaat attttattat tgcatccctt tatcctattt tgtatagatg taaaaaagct
    56641 caacatggat acatgttgag ctaaatgtgc taaatacaac atacctgcat cttcccttta
    56701 tcttgtttaa gatagctctc catcaaaatt cgggataatt ttgatgacag tactgtacct
    56761 attaaataca gtcccagcac tagcttcgga cactagcact tcggcactta ctccttttat
    56821 attgcctcat tggtttccaa cctcttcaat attaatctta gtaaatgcaa cctctacctc
    56881 aatctgtttg ttagatgagg taattcttat taatttttat taattcaaag taattgtagc
    56941 ataatatgtc gagattgtaa atattttcag tataataatt cttactttat gatttcattc
    57001 catttttcac aaataatttt ttctccatat aatttaaata ctgtagtata ttttaaatac
    57061 acacaaactt tccacaaatt ttaaattatt ataatacctt tataataaaa aataaaagct
    57121 atgtaaactt atcaatttac acagctttat atacattaat ctactccaag tacagcttta
    57181 agctttgatg ctattgtaat aactcgtgga ccaaatataa cttgaactga gtttttcttt
    57241 ttaacaactc cacttgcacc caattcattt acccagaagc catcttcata gaatccatca
    57301 attgaattta gctctaccct aagtctagtt gcacagtttg taacattttt tatattatta
    57361 cttcctccta aaccttctat tatagaatgt acaagctttg tatctttatc atctacttcc
    57421 tcttctactg cattgttgta tgctgtttta ccagcatcta cagattgtct ttctctatat
    57481 tctttcttac tataaagctt aacttcttct gaacttcttc ctggtgtttt tatatcaaac
    57541 ttcttgattg cccatgtaaa tattatataa gtaactataa aaaatattgg tatcaaaaat
    57601 aataatggta acgcatccac tttttgtggt tgtaataaat taggaaacat atttctaaat
    57661 gattctccca ttatagaaac attaaacatt tctgtaaata catacgtcaa tcctgccagt
    57721 ggtacatatg ctacaaaata taataatggt gcaacaaata ggaatgtata ctctattggt
    57781 tccgttaccc ctaccaacat ggctgttact attgctggta tcaatatact tattgctttt
    57841 ttcttattag cattatcagc caacttatac atagctaaag ctgctgctgg taatattgca
    57901 aaatgtatta ataaacgacc tgttgtgaag ttacgagtta tataagatag tgtatctggg
    57961 tctcccattt gagctaatct tatattatta acaccctcgt aaattgctcc acctacttcc
    58021 attgttccac ctactcttgt atattctata gggaatgcaa ttaagtgatg tataccaaat
    58081 ggtaataatg ctttatccat tgctccaaaa gtaaatgttc ctaataatcc actagaacct
    58141 atccaattac caagtttaga taatgccaac cctactggtg gccatataaa gtacattgct
    58201 gtacccaata ctattgatgc tataaacatc ataatcattg aaaatcttgg acctgagaaa
    58261 aaagataatg cactaggaag ttctatgtca acaaatttgt tatgtactgc actagctaca
    58321 aatccagcta ttatagctcc aaatatacta caatcatatg aaaagattcc taagaaagaa
    58381 ccatataaag aacttcgact atatgcttct gcctctccta atccagatgc cataaacgct
    58441 tctgctgtaa ctgtatctga atttatacca tttgctgcta acaatgtact tataactgtg
    58501 tgcattccta taaataaaac aattcctcct aatgcacccc atcctttttc ctttttagat
    58561 aatccaaagg ctatacctgt aacaaagaat attggtaagt atctcattac cataaatcct
    58621 aaatcgttta ttactttaaa gaatacattt ataaatgacc cttcttttat tagtccgcta
    58681 agccctaatg cagaaacgtt ttccatattt gcaaaagctg accctaatcc tataaatact
    58741 cctgctacaa caagtaatat aacaggtatc atcattgctc cagaaagtac ttgtaattta
    58801 tccttcatag tattatttcc tccattttta ttgaaatgcc aggctatata atgcatatat
    58861 atatacttct attgctttgt ataatgtatc tatacttata ttttcatttg cctgatgtga
    58921 atttggatta tccccctcta ttgtgggtcc aaatgcaact ccatttttta acactcttgc
    58981 ataagatgca gctccttttg taaaaagttc ggcttctttt ccaaaacctt gtttatatgc
    59041 atttgataat ttatttatta attcactatc tggttttaca tacagtaatt ttaaatcctt
    59101 atatatatca actattaaat tttctttttt tccaatttca ttaattctat tagttataaa
    59161 ctcccaactt atacccttag gatatctaaa gtctattttc atattcaatt catttttctc
    59221 taagaagata ctcattatac atattgtaga aactcccata tctacatctt ctttatacat
    59281 ccctaatttt tttccatgat tatcatctgt aaagtatgaa tttaaaatat cccttattat
    59341 aacgccttta tcatttagtt ttttaatttt ctctaaatct tttgctaaac taaatgcaca
    59401 gttatatgac ctgtgtggat ttctcgataa agccctttct cctgtatatc ttactaatac
    59461 tttaccttca tctaattctt ctatctctgt ataataagct aatgattcta ctaaatcttt
    59521 cttatcatta gttttaaaaa cagcctcaat tttgtcacat acaaatccat cttctttgtt
    59581 tgactttata tcaactaaat tgtgatttct aaatttatct ttatctattt tctttcttag
    59641 attgaagtat aaaatacctt tttctccatt tactattggg aagtttccat ctggagaaaa
    59701 tgcaaatttt ggctgttcat tgacactaaa gtaatgctcc atacattccc aagtcgtctc
    59761 ttcagctcca cccactatca atctaatctt tctcttcggc ttttcattaa gttctcttaa
    59821 gaaaagtaat gcatataaaa tccctatcaa aggtcctttg ttgtcattaa ctcctctacc
    59881 ataaagatag ttatcttttt gacatacttt aaaaggttta ctcttccaaa gttctttatt
    59941 atatattggc accacatcta tatgattaag cacccctact acttcttctc cttctccata
    60001 ttctatatga attgcatatc catcaaagtc ttttacaaca aaatctttgt cttttgctat
    60061 ttgaataagc ttatcgaagg catttcttat ttctatccca aatggttgat ttatatctgt
    60121 tgtactttca tctctaattg aaggtatttc aactagactt ctaatatcat ttatgatatt
    60181 ttcttgattg gattttaaat aatcaataat tagttctttg tttactatca tcttaattat
    60241 ttatcacccc tttatattaa ttttacaaag catttcagtt catatctaca ttataaattt
    60301 tgaatattat tttttcaata tttcaaatac ttctctaagt taccataatg atacggtaaa
    60361 caatcaacag attatgacaa aatcatacta tacctattac taatatttta acttatctat
    60421 tacgtctttt ttaatgtaag tttattccaa aaaatacata aaaaaagatg tagccttagc
    60481 tacatcttct tatatctatt caacttccat tattatgcta ttaatatcta catttccagg
    60541 ttctatccta tcttttactg ttctcttaac agaatcagca tcatccatta taactacagg
    60601 agttattata tttaaatcat ttgacgttat aaaatctaaa tctgcttcca ttattaaatc
    60661 tttagctttt accttatctc ctgcctttac cttaacatca aacggctttc cttctagtga
    60721 cattgtctct aaacctacat gtattaatat atttgtatta tcattactct taatcattat
    60781 tgcatgcttt gtatcaaata cattgactat ttcaccatca acaggagaat ataacttacc
    60841 ttcacttggt attattgcta ctccatctcc catcatcttt tgggcaaaaa ctgcatctgg
    60901 aacatcttct aagttcacta aatttccctt aaaagggcta tatattttct caatcttatt
    60961 ttcttttttc ttaaatatat taaacataac acactctcca cattataaaa ttttatgata
    61021 atatttttct taaagctttt gctacaccat catttacatt agtatcagtt acaaaatctg
    61081 ccatagattt tacttcatct gtagcatttc ccatagcaat accaagacct gcaaatttaa
    61141 tcatggatat atcattttca ttatcaccta tacaaataac ttctttgcta tctataccta
    61201 atatatcaca aaatttttta actgcaatac cttttgaagt acctttactc ataacttcaa
    61261 agtttatctt tccagaactt actacttcta aatcttcttg ttttttaaat tcttcctttg
    61321 cttctctcaa agaatctacg ttttctgaga aaagtataca ttttaaaatt tcattatcag
    61381 ctttttctaa taaagtttca caacttgcat tttctattat ttcaattctg tcttcttctt
    61441 tatttttact atttattaat ctatatggat gttcttcacc tatttcattg ttggatataa
    61501 ctattttaca gcctttaaaa tgtttgctta aattatactt ttcacctatt gtatagattt
    61561 tctttagagc ttctttgctc aaaaccttct tatactcata tcccagtaat ttaaaatatg
    61621 tcccattagt tgatataata tatatatcat cccctaaaac acttgtaaaa tatttcatag
    61681 cattataagg tcttcccgta actaaggcta ccttgatacc cttttccatg gcttctttta
    61741 gtgctttaat attttcttct gatacttcaa atcctttacc catcaaagta ccatccatat
    61801 cagtacaaat taatttatat cgcatttgta tcacatccta gtaagatttt tctaatattt
    61861 caacaaggtc ttctttcttt ccaaaaggta aaaatcctaa aactggacag cttgttattt
    61921 gttctaattg ttcctttgtt acattaaact cagacatttt tgtcttaagc cccactctct
    61981 ttaaaaaact ttctatttca tttcctaaag ttttagctgc ttcatcatct tccacttttt
    62041 ctaattcttg gtttagtatt ctcgctactt tggcaaattt ctctatatta tccttataga
    62101 acttttctgc aaattttggg aacactatag ccaaagcctc accatgagga atatgtgtaa
    62161 ctcctcctat tatttcactt agcggatgtg gtgctgctgc tccagcattt gccagtgaac
    62221 ttcctcctaa tgtatctgct actgctaact ttgttctgta ttctatatta tttttatctt
    62281 ccattacttt aggtagatac ttaatgacta attccataga tttttcagac attatctctg
    62341 taaagtcatt agcatttgga tttatataac tttcaaatgc atgagtaaaa gcatcaaatg
    62401 ctgttgatgc agtaattctc tctggcagag ttaacataag ctctgggtca actatacatt
    62461 cttttgagaa acaattttga tgaaatattg tatttttctc gcttcctctc gatattactg
    62521 ctgcttgtgt aacttggctt cctgttccag aagtagttga tacagctatt aatggtaatt
    62581 ctttttcact taccttatcg tatattttaa atggatttgt atatgtacta aacatataat
    62641 cccaatctat cttttctaaa ccaaaagtca atgctaatac ttttgcagta tctatacttg
    62701 aacctcctcc aacagctaaa acaacatcta cagattcttt tttagctaat tcaaaccctt
    62761 cgtttattaa ttctacagtt gggtttggct ctactctctg aacctcccat gactaaagtc
    62821 acagggttcc tgcttcacag aattttgcat actaaaatat gtcttactaa ttctccacag
    62881 gccatccccg tagttcctac ggttcttaca taagttattt attttgaatt gttattagtc
    62941 ttaatccttc ttttaatata tttatacttg catttatatc tctatcgtga gtttcattac
    63001 aactaggaca aatccattct cttatattta agtccttcac ttcctcgttt ttatacccac
    63061 atttattgca tatttgtgaa cttgcaaaga atttacctac ctttacaatt tgtctaccat
    63121 gccaattagc cttgtattct aattgacgaa taaattctga ccatgataca tctgaaattg
    63181 agcgagatag tttacgattt ttaatcatat tctttacttg taaatcttct atgcaaataa
    63241 tatcattctc ttttattaat ttagtagata atttttgcag aaaatcattt ctttgattag
    63301 ctatatgttc ttgaagtctt gcaactttta atcttgcttt atttctattt aaactaccga
    63361 ttgtttttct cgataattct ctttgtaatt tagcaagttt gtttaatgac ttcttaagat
    63421 acttaggatt ttctataaat tctccacaac ttgagataca aaattcttta attcccaaat
    63481 ctaaacctat atgattatta gtattttcaa atgcttcaat atctacatca gtacagcata
    63541 atgatacata atatctacca cttggttctt tagatatagt agcattaagt attctacctt
    63601 gaggtacttg tttatccctt atcttaacca taccaagttt aggtagtttt atatattgac
    63661 cacaatacat aatgtttcca tttgtaaagt tagttttata tgaaaatcta ttaattttct
    63721 ttgatttaaa tttaggaaat cctgcttttt ctttaaagaa ttttttatat gcattatcta
    63781 aatcttttaa ggcgttttgt agtgaaaatt tgtcaggttc tttaagccaa tttaattctt
    63841 tttttaaatt ggttaaatca gaactacact gtttataagt aaaagtttct ttatcgtttt
    63901 tataaacttc tattctttta gcaagatact tattatatac aaatctacaa catccaaaag
    63961 ttttgttaat taactcttg
//
LOCUS       DAEPUT010000010        61088 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.010, whole genome shotgun sequence.
ACCESSION   DAEPUT010000010 DAEPUT010000000
VERSION     DAEPUT010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61088
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.010"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(162..761)
                     /locus_tag="KRL22_000763"
     CDS             complement(162..761)
                     /locus_tag="KRL22_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271281.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(962..1174)
                     /locus_tag="KRL22_000764"
     CDS             complement(962..1174)
                     /locus_tag="KRL22_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBH1271282.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(1247..2962)
                     /locus_tag="KRL22_000765"
     CDS             complement(1247..2962)
                     /locus_tag="KRL22_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1271283.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(2962..3516)
                     /locus_tag="KRL22_000766"
     CDS             complement(2962..3516)
                     /locus_tag="KRL22_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBH1271284.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(3509..4111)
                     /locus_tag="KRL22_000767"
     CDS             complement(3509..4111)
                     /locus_tag="KRL22_000767"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBH1271285.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNWGTITELESKAHKFIEYMKENWRE"
     gene            complement(4120..6768)
                     /gene="polA"
                     /locus_tag="KRL22_000768"
     CDS             complement(4120..6768)
                     /gene="polA"
                     /locus_tag="KRL22_000768"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBH1271286.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            6920..7007
                     /locus_tag="KRL22_000769"
     tRNA            6920..7007
                     /locus_tag="KRL22_000769"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6954..6956,aa:Leu,seq:caa)
     gene            complement(7194..7637)
                     /locus_tag="KRL22_000770"
     CDS             complement(7194..7637)
                     /locus_tag="KRL22_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271287.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
     gene            complement(7640..7837)
                     /locus_tag="KRL22_000771"
     CDS             complement(7640..7837)
                     /locus_tag="KRL22_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1271288.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(8029..8895)
                     /locus_tag="KRL22_000772"
     CDS             complement(8029..8895)
                     /locus_tag="KRL22_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1271289.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(9121..9990)
                     /locus_tag="KRL22_000773"
     CDS             complement(9121..9990)
                     /locus_tag="KRL22_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1271290.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(10496..10717)
                     /locus_tag="KRL22_000774"
     CDS             complement(10496..10717)
                     /locus_tag="KRL22_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271291.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(11218..12198)
                     /locus_tag="KRL22_000775"
     CDS             complement(11218..12198)
                     /locus_tag="KRL22_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271292.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(12362..13234)
                     /locus_tag="KRL22_000776"
     CDS             complement(12362..13234)
                     /locus_tag="KRL22_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1271293.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(13398..13949)
                     /locus_tag="KRL22_000777"
     CDS             complement(13398..13949)
                     /locus_tag="KRL22_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1271294.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNESTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(13969..14871)
                     /locus_tag="KRL22_000778"
     CDS             complement(13969..14871)
                     /locus_tag="KRL22_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH1271295.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRTQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(14886..17258)
                     /locus_tag="KRL22_000779"
     CDS             complement(14886..17258)
                     /locus_tag="KRL22_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HBH1271296.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(17479..18168)
                     /locus_tag="KRL22_000780"
     CDS             complement(17479..18168)
                     /locus_tag="KRL22_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1271297.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITNSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYVK
                     FIYNLFKSLTDTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(18409..19788)
                     /locus_tag="KRL22_000781"
     CDS             complement(18409..19788)
                     /locus_tag="KRL22_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1271298.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPYLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEVCLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENINKYIRIKGTITRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(19782..20495)
                     /gene="rgbR"
                     /locus_tag="KRL22_000782"
     CDS             complement(19782..20495)
                     /gene="rgbR"
                     /locus_tag="KRL22_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HBH1271299.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(20746..21306)
                     /locus_tag="KRL22_000783"
     CDS             complement(20746..21306)
                     /locus_tag="KRL22_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HBH1271300.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKTNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(21401..22204)
                     /gene="zupT"
                     /locus_tag="KRL22_000784"
     CDS             complement(21401..22204)
                     /gene="zupT"
                     /locus_tag="KRL22_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBH1271301.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(22355..23518)
                     /locus_tag="KRL22_000785"
     CDS             complement(22355..23518)
                     /locus_tag="KRL22_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1271302.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAILEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(23578..24765)
                     /locus_tag="KRL22_000786"
     CDS             complement(23578..24765)
                     /locus_tag="KRL22_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271303.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(25128..26828)
                     /locus_tag="KRL22_000787"
     CDS             complement(25128..26828)
                     /locus_tag="KRL22_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271304.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(27083..27358)
                     /locus_tag="KRL22_000788"
     CDS             complement(27083..27358)
                     /locus_tag="KRL22_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1271305.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(27477..28049)
                     /gene="mobB"
                     /locus_tag="KRL22_000789"
     CDS             complement(27477..28049)
                     /gene="mobB"
                     /locus_tag="KRL22_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBH1271306.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(28033..29214)
                     /locus_tag="KRL22_000790"
     CDS             complement(28033..29214)
                     /locus_tag="KRL22_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBH1271307.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILDLEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(29425..30159)
                     /locus_tag="KRL22_000791"
     CDS             complement(29425..30159)
                     /locus_tag="KRL22_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271308.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            30521..31426
                     /locus_tag="KRL22_000792"
     CDS             30521..31426
                     /locus_tag="KRL22_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1271309.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(31586..32428)
                     /locus_tag="KRL22_000793"
                     /pseudo
     CDS             complement(31586..32428)
                     /locus_tag="KRL22_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
     gene            complement(32412..33170)
                     /locus_tag="KRL22_000794"
     CDS             complement(32412..33170)
                     /locus_tag="KRL22_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1271310.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(33187..33657)
                     /locus_tag="KRL22_000795"
     CDS             complement(33187..33657)
                     /locus_tag="KRL22_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1271311.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(33657..34400)
                     /locus_tag="KRL22_000796"
     CDS             complement(33657..34400)
                     /locus_tag="KRL22_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HBH1271312.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            complement(34404..34817)
                     /locus_tag="KRL22_000797"
     CDS             complement(34404..34817)
                     /locus_tag="KRL22_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1271313.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(34843..35595)
                     /locus_tag="KRL22_000798"
     CDS             complement(34843..35595)
                     /locus_tag="KRL22_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1271314.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            complement(35835..37229)
                     /locus_tag="KRL22_000799"
     CDS             complement(35835..37229)
                     /locus_tag="KRL22_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH1271315.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            complement(37249..37458)
                     /locus_tag="KRL22_000800"
     CDS             complement(37249..37458)
                     /locus_tag="KRL22_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HBH1271316.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            complement(37487..38932)
                     /locus_tag="KRL22_000801"
     CDS             complement(37487..38932)
                     /locus_tag="KRL22_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1271317.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            39042..39836
                     /locus_tag="KRL22_000802"
     CDS             39042..39836
                     /locus_tag="KRL22_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH1271318.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKNKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLRGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            39887..41209
                     /locus_tag="KRL22_000803"
     CDS             39887..41209
                     /locus_tag="KRL22_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH1271319.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(41309..42526)
                     /gene="cdeC"
                     /locus_tag="KRL22_000804"
     CDS             complement(41309..42526)
                     /gene="cdeC"
                     /locus_tag="KRL22_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HBH1271320.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNSECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(42709..42889)
                     /gene="ssrS"
                     /locus_tag="KRL22_000805"
     ncRNA           complement(42709..42889)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KRL22_000805"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(43004..43909)
                     /locus_tag="KRL22_000806"
     CDS             complement(43004..43909)
                     /locus_tag="KRL22_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271321.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            44121..44519
                     /locus_tag="KRL22_000807"
     CDS             44121..44519
                     /locus_tag="KRL22_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271322.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            complement(44642..45658)
                     /gene="ccpA"
                     /locus_tag="KRL22_000808"
     CDS             complement(44642..45658)
                     /gene="ccpA"
                     /locus_tag="KRL22_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HBH1271323.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(45911..46111)
                     /locus_tag="KRL22_000809"
     CDS             complement(45911..46111)
                     /locus_tag="KRL22_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271324.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            complement(46145..46324)
                     /locus_tag="KRL22_000810"
     CDS             complement(46145..46324)
                     /locus_tag="KRL22_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271325.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            complement(46506..46712)
                     /locus_tag="KRL22_000811"
     CDS             complement(46506..46712)
                     /locus_tag="KRL22_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271326.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(46760..47185)
                     /locus_tag="KRL22_000812"
     CDS             complement(46760..47185)
                     /locus_tag="KRL22_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271327.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            47357..47584
                     /gene="acpP"
                     /locus_tag="KRL22_000813"
     CDS             47357..47584
                     /gene="acpP"
                     /locus_tag="KRL22_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH1271328.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(47728..48732)
                     /locus_tag="KRL22_000814"
     CDS             complement(47728..48732)
                     /locus_tag="KRL22_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBH1271329.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVMFYEEK
                     "
     gene            complement(48746..49648)
                     /locus_tag="KRL22_000815"
     CDS             complement(48746..49648)
                     /locus_tag="KRL22_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH1271330.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSIA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            complement(49843..51018)
                     /locus_tag="KRL22_000816"
     CDS             complement(49843..51018)
                     /locus_tag="KRL22_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH1271331.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNVDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            complement(51105..51950)
                     /locus_tag="KRL22_000817"
     CDS             complement(51105..51950)
                     /locus_tag="KRL22_000817"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HBH1271332.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(52048..52845)
                     /locus_tag="KRL22_000818"
     CDS             complement(52048..52845)
                     /locus_tag="KRL22_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH1271333.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(52864..53874)
                     /locus_tag="KRL22_000819"
     CDS             complement(52864..53874)
                     /locus_tag="KRL22_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH1271334.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(53893..54675)
                     /locus_tag="KRL22_000820"
     CDS             complement(53893..54675)
                     /locus_tag="KRL22_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1271335.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(54734..55870)
                     /locus_tag="KRL22_000821"
     CDS             complement(54734..55870)
                     /locus_tag="KRL22_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBH1271336.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(56579..57046)
                     /locus_tag="KRL22_000822"
     CDS             complement(56579..57046)
                     /locus_tag="KRL22_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HBH1271337.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKKGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            complement(57125..57667)
                     /locus_tag="KRL22_000823"
     CDS             complement(57125..57667)
                     /locus_tag="KRL22_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271338.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(57719..58405)
                     /locus_tag="KRL22_000824"
     CDS             complement(57719..58405)
                     /locus_tag="KRL22_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH1271339.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            complement(58405..59265)
                     /locus_tag="KRL22_000825"
     CDS             complement(58405..59265)
                     /locus_tag="KRL22_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271340.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            59400..60200
                     /locus_tag="KRL22_000826"
     CDS             59400..60200
                     /locus_tag="KRL22_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HBH1271341.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTDLI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            60225..60794
                     /gene="yfcE"
                     /locus_tag="KRL22_000827"
     CDS             60225..60794
                     /gene="yfcE"
                     /locus_tag="KRL22_000827"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBH1271342.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDVLVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
BASE COUNT        19685 a        10822 c         6302 g        24279 t
ORIGIN      
        1 tattaagtta aaaatttgaa tgatgatgac caattaccaa atcatggtaa attatttaaa
       61 agaatatgtc aaaaaaagaa taagctcttt caaatgcata aaaaatttat acccaagtta
      121 tacttaatca tgcaaattgg cagaacttat tctttaaaac tctaactttt aagtttttct
      181 ttgataatat aatttattac tttttttcta atatcttcag cattataatc atcttctact
      241 tctatatcca aaagttttgc tattgacctc atatcttctc tagtctttga cctatagctt
      301 gatattaatt catcttttat tttctctggt tctaaaagat attcttcatc tcctcttttg
      361 aaaacaacgt atttttgagc atatgaactt ctattgtagt atatatatct tgatattttt
      421 cttaaaattt gattatatga aagtcgcttg ttaatatcaa gttttaagta ctctgaaaaa
      481 gcaaatagct ctttttttga tttaaataat gcttctttct ttatagtcct tgatattgaa
      541 gttacacttt cttgatatgc acactttttt aacattttta aatatactct attaagacca
      601 atactttgat tgaatttttt tatattatta ttaataatct tatccaagtt accttcaaag
      661 tatttttttg ctcctttttg tgatacataa ctctcaagtt ctttgtgggc catatcaagt
      721 atcatttttt ttaaatcctc tttatatcct ctagattcca tgatactccc tcccttagct
      781 atttatagta tattcaaaaa gctcaagaaa tgtgagtcat tacaaaattt ttttactttt
      841 tatgtatata ttaatttaaa aggggagata atagtaatgt aaaatcaaac atactcaatc
      901 tcccccattt ttagacctct attactcccc caatagaggt ctttttttag tttatcaatt
      961 tctattcaat tccctttagt tcaaatccta attctgctat cacttctttt aatttttcaa
     1021 tagatacatc atctttcata tctacagatg cacacttatt ttctaaatct acatctaaaa
     1081 cttcaatacc atctatatct tctgttaatg cagttttaag atggtttaca caatgaccac
     1141 aactcatacc ttctactaat agtttcttct tcatttaatt acctccttat accctataag
     1201 ggtattctat catatagttt atacttttta aatagaaatt aatcatttaa tttgattcat
     1261 tcgattttat atctaaatta gatattccct catatacatc aaaatcattt ggagtaattt
     1321 taccttttaa tctactatta cttacaatat agttgtttct cacagctaaa cttataaatg
     1381 ttgcattatc ttttatatat gtctgtacat ctttgtatgc tttttttgtt tcaatttcag
     1441 acgtagaact tgtaagtgca gacatatatc catttaactt atcatcagta tatccactac
     1501 tcgctataat actacttgca tctggtataa ttgatagttt ccatccaact aatgctaaat
     1561 cataattttt agaattaaga gcattttcca tatccttatc tgacagctga tttactgtac
     1621 tatttattcc tatagctttt aagttttcat ttattatgtt tgcagttttt attctctcac
     1681 tattatctct gtttactatt atctttaagt tcatttcaga aagacttttc tttacttcct
     1741 ctttttctct attttttttc tcttcagctt cttttttgat tctatcttct tctgcttttt
     1801 tagcttttgc ttcttcttct ggcgtaagct tctttgagtt ctttttagct gattttttct
     1861 gattttttac tttattgtca ttttgattta ctgagtttac atttgcatat tctaccttag
     1921 caagacactc tatcgcctta tctttattaa actctaaatc cttcatttca ctattatagt
     1981 attttgattt tgaattaagt ggaaaattaa ctggagtagc atcatccata taaccttcac
     2041 taataattct atctttatct atagagtgtg caattgcttt tctaaaatta acatctttga
     2101 aaaaaggatt attataatta aataatacac actcataatc tcttccttga tattttgtta
     2161 tattaaactc tttttcttga aacttactta aatcatttaa tgtaacattg gttatatcac
     2221 tatcaagagc cataaccata gatgtccttg catcttcatt aggcaccata cctactttta
     2281 tgttcttcat ggtttttgga acttcttcat agtaatcttt gtttacagat aaaaccattc
     2341 cttctctttc tgtatatgat tctattttat atttcccatt tcctatcata ttattattct
     2401 tgtcatttac atcttttgaa tctaaatgat tttgagatac aattggaaaa attaaactat
     2461 caattgaaaa agcatatcta gctttaaatt ttattgtaaa atctttatct gatttaatat
     2521 tcacagaagc tatattttta gtaaattcat tatatggact atctgcactt ttttgaatta
     2581 aaccaatagt atagtttaca tcatttgaag taacattttt tccatcatgc cactttgcat
     2641 cttttagctt tatatctata ctcattccat cctgagctat attatactcc ttaactaatt
     2701 gaggaattac attgtagttc tcatctatag taaataaact atcataaact aaattcatta
     2761 tataaccaac agacttatca gtattagtta taggatttat agtttttgga gttaccattg
     2821 ttaagtttat atacttagca tctatcgaac tttgactttg taaacttgaa tcactactac
     2881 tttgttttgt tttagtatta ctacaaccag ctaccataag agttatagct aaaacgactg
     2941 ttaagacttt tattctcttc attagttttt tcctttcttg ccatatatct tattataatg
     3001 ttcgtaatta ttttttactt tttctacata ttttgaagtt tgcttaaaag gtatatcatg
     3061 tagattttcg ccatctttac tatattcatt attttctaac cattttttca cattacctga
     3121 accaccatta tatgcagcta tcactaaatc taatttacca aattctttgt ataacttact
     3181 taaataccaa cagccaagtc ttatattagt ctctgggtcg aaaatatcca cattttttaa
     3241 atttagttcc tctgctcccc aatctctagt tatgtctaat atttgcatta atccttttgc
     3301 ttcctttttt gaaacagcag aactattaaa cttactttcg gctttaataa cactgtaaac
     3361 tatattttca tctaaattaa attctttcga atacttttct acatactctg aatatttttt
     3421 aggatataaa aatttatgta ttactttgct ttccattaat agtgccccaa ataagattat
     3481 aaaaatagat agaatcaata ctttcttact attcacgcca attctccttc atgtactcaa
     3541 taaatttatg tgctttactt tctaattcag ttattgttcc ccaattatct attatataat
     3601 caccatattt ggatttttct tcctgactca tctgtgaatt tatcctacta agtgcttcct
     3661 gctcactgca attatctctc ttttgtattc tactaatttg tacttcttgt ttacaagtaa
     3721 ctactaatag cttgtcaacc atatctaaaa aaccactttc taccaatatt gccgcatcta
     3781 acactactat attttcgcct ttttttctca atttttctat ttcacttatt attttttctc
     3841 ttattcgtgg atgagtcaag ttatttaatt ccttaagttt ttcttcatca ctaaaaacta
     3901 ttttcccaag agcttttcta tttagagttc catcatcatt ttttatactt tgcccaaaat
     3961 ggacaaatac tttttccaat aacaacttat cctcaaatat cttcctggat ataatatcag
     4021 catccactat aggaatgtta agatttctaa atatatttga taggctgctt tttccacagc
     4081 ctattcctcc tgtaagtcct aatatcaaca taaaatcacc tactttgtct cataccaaga
     4141 actacctaca tttaaatcta catctaagtg aacatccata tttacagcat tttccatttc
     4201 ttcttttact attttcttaa ctatatctat ttcatcatca attgcttcaa ctatcaactc
     4261 gtcgtgaact tgtagtataa gttttgattt caaattgttc tcttccaatt ttttatgaac
     4321 atttatcata gcaattttta ttatatctgc tgcacttcct tgtattggtg cattcattgc
     4381 aaatctcttt cctctatttc tttccataaa attgcttgac tttatttctg gtatatatct
     4441 tcttctgttt aaaattgtta cagcatatcc atcctcacta gccttttcta ctgttgtgtc
     4501 cataaactct tttattttat ggtatttagc aaaataactt tcgatatatt ctttcgcctt
     4561 tggaacaggt atatttaaat catcagctag accaaagtca cttttaccat atataatacc
     4621 aaagtttaca gctttagctg cacctctcaa ttcactagta acatcttcca taggaacatt
     4681 aaaaacttgt gaagctgttt tggtatgaat atcttcatga tgtttaaatg cttctatcat
     4741 attttcatcc tgactcatat gtgcaagaac tcttagctct acttgtgagt aatcggcatc
     4801 aaccaactta cagttatcat ctgcaataaa cacttttctt atttttctac ccatttccat
     4861 ttttataggt atattttgaa gatttggttc tgtagatgaa attcttcctg tagtcgttat
     4921 agtttgatta aatgatgaat gtattctatt actttctgga tttattatat ttaaaagtcc
     4981 ttcaacgtaa gtagaattta actttactat ttgtctatac tcagttatct tatctattat
     5041 tggatgctta tctcttaatt tttctaaaac atctgcatta gttgaatatc cagttttagt
     5101 ttttttaatt attggaagct ctaatttttc aaataatata acacccaatt gttttggtga
     5161 atttatattg aatggctctc ctgataattc ataaatttcc ttttctaatg tagctattat
     5221 ttctttaaat tcaacactca attcatccaa tatacttttg tctactttta taccttcata
     5281 ctccatatga cctaagactt ctactaaagg catctctaca tgataaaaaa gaccatccat
     5341 actcatatcc attagacttc tttccatcat aggaactgtt tctttaactg tgcatattat
     5401 ttgacccata tactctgcta aatcctcaaa ttctaaatcc tcatagtttt tagatttaac
     5461 accctttcct aataattctt cttttgattt aacctttttt gataaatact tcatagctat
     5521 tgcactacaa tcatatgagg tagatgaagt tgaatctatt aagtactcag ctattgttat
     5581 atcaaaatac atattttcta agtttatatt atatggtttt aaagatatat aatcatcttt
     5641 taaattatat ccatactttt taatttcatt atttgaaaat atactatcta actttgacac
     5701 ttcatttgaa tctacataat atattttttc tccatctaca cttataaaaa tatatattat
     5761 atttttttca agtatattac cttgtcctct aacagttttt aaaataactt gtcctttttt
     5821 gtttacttca tctataaatt tttctatatc ttttaatttt aatatttcta ttttttcttc
     5881 tacgtgttct gtgtcatctg aatcgaccaa atcaactaat cttgataaga gacttgtaaa
     5941 tccaaagtat ctaaatttat ctaaaagttc atctttatca taatcgccaa aaatcatact
     6001 atctaaatcc acttctattg gcacatctct tataattgtt gcaagtcttt tactttgaat
     6061 agctatttct ttgttttcct ctattttctt ttttacacta cctttaagct tatctgtatt
     6121 ctctattaga ttctctatac tagaaaactc ttttataagc tttatacctg ttttttcacc
     6181 tattccaggt actccaggta tattatcaga cttgtctccc ataagaccct ttaaatcgat
     6241 aaattgtgtt ggagtcatct cgtatttttc aattacagaa ttaaagttgt attcttcaac
     6301 ttctccaact cctttttttg ttataagagt agttgtattg tctgaagcaa gttgaatagc
     6361 atctttgtct ccagttacta tgtatacctt atatccattt tcttctgctt ttttagaaac
     6421 agtacctata atatcatctg cctcatagcc atctatttcc aatctattta ttctaaattt
     6481 atctaaaagg tcttttaatg gctgtaattg ttctgccagt tcatctggca ttccctttct
     6541 tccagcctta tactctttat attctaaatg tctaaatgta ggtgcttttc tgtcaaatgc
     6601 tacacttata tgtgttggtt tatatatatc tatcatttta aatagcattg ttgtaaatcc
     6661 atatattgca ttggtcttta gcccttcttt attattcatt tctggaagag cataaaaagc
     6721 tctatttatt attgaatttc catctattat aattaatttt ttttccaaat tatatcactc
     6781 ctaaaaatta tctatttttg taacatatat attatatacc aatatactgt tatttaatat
     6841 tcccataata ataatagtat attaaaatta aatatgttgc aaacaatata tttttttgct
     6901 ataataatat acatgacatg cccgagtggt ggaattggta gacgcagtgg actcaaaatc
     6961 caccggacta atactccgtg ccggttcgag tccggcctcg ggcaccatta aaaactccta
     7021 aagctattta ttcaatagat taggagtttt tttatttttg atttaaattt taagttattt
     7081 tttgaaatta ctgtgtcttt ttaaaattta tataattata taaatttatc ttctagcatt
     7141 aatttaaaaa ctaatttatt tttatataat tttctatttt atatcataac ttattacaac
     7201 tttttatcta atttattgta tacaacaaca ctacaaataa attgaaataa aataagcaat
     7261 ccaagaacaa ctaaaaccca cttgcttatt accattacag aaaatacact caatatagaa
     7321 acaataaata taagaattac aagaacatag gacatgattt gattagtgat acgtccagct
     7381 ttatcacgta acataattct tctttcatca ttcatctcta tcctttgatt ttttatcttt
     7441 tcttcataat ctactgctct ttcaggttta ctccaataca tatattgaag aatcatacat
     7501 acacctggac ctaaagcagc tccagataat ccccaaataa aagcctcaaa tgaaaactca
     7561 gtaaatgtag ccaataaaac aagtaaaatt ccacaaataa aatatataat tccaacatat
     7621 aacatattct ttttcatttt tactcctcct cataaataaa tatttcttca atactcatat
     7681 caaagtatct agctatctta aaggctaaga tgatagaagg attataccta ccattttcta
     7741 atgaacctat agtttgtctt gatacttgca aaatagaagc aagttcttct tgttttatgc
     7801 ctctttcttt tcttatttct tctaatctat ttttcacatc tatccccctt taatatctca
     7861 actacggaaa gtctactttc cataattata caactatatt ccatttatgt aaagcttact
     7921 ttccatattt acaaaaaaat aacagactat tttcagcctg taattttaga atttcatgtt
     7981 gtttattaat tttaatgtta tttattaatt ccatattatt tattaatttt aacttggttt
     8041 ctgaattgga atccaaactt ctgtagtata atcaggagca ttgatatcgc cattgggata
     8101 aagttcaata tctggtaaat tagcatacac atacccagaa cttggtaacc actcagtaat
     8161 aattcttttt tgcaattcct gtattgccag agcatttggc attggagaaa cacattcaaa
     8221 tactgcccat gtgcctgatg gtattaagta ttcatgagta tcttctaata caggcttatc
     8281 tgttggagca gcaatataat aatctaaacc cttactattt gtacacacac taactccaag
     8341 caatccacaa ggttcattat ttattaactc tgaaagttta tcaattgttc cattttttat
     8401 gcatttagcc cacaacttag gaactttctc aaagcactct tctacaatca tgttcatact
     8461 ttcttttata ccaacaatac gaaacccttt cttttctaca atacgatatt gcatttctat
     8521 atttcctttt acataaatgc ttaatgtcat cttaggatat gcttttaaaa caacaccctt
     8581 tgctctagct gcagatggag aaatgttatg tatattttga aaagctctat taaaagatgt
     8641 tggtgaatcg taaccatact tctcagatag ttctaaaatt ttgatgttac tgttctgaag
     8701 ttcaaatgca gccttagtca tacgtcttcg tctaatatat tcagataatg gtacttctgc
     8761 aatatatgaa aacattcttt gaaaatgaaa ggttgaacaa catgcaattt ttgctgcttc
     8821 tgcataatcc actccacttt cgagattttc ttcaatataa gtaatagctt gatttaattt
     8881 atttatccat tccatttgat attacctcca agcaaattat acagtttaat aaaataatat
     8941 acctctctat tcatgcacaa aattgtaagc atttaaattc ataagtattt ttcaatcaat
     9001 acaataaata taaaaattgt attatacaat aaaaaagttc aataacatta tattataaaa
     9061 tgttattgaa ctttttataa aaattaattt aagtgtagtt aaattaagta ttacactatc
     9121 ttatatatta caatatccta ctatcttata gtcttctggc actttataat ctttgtctgg
     9181 agtacctaaa ttccatttta aatcaaacat agttgcactt attattgttg caaaataaag
     9241 cataactata ccaatgtcta ttttttcttc atataaatta gtatgaccat cttttctaac
     9301 agctaaaact acagtgcctc catcaactat aaatctccat ggttgtctat ttaatgtaga
     9361 tggagctaat cttgcatagt gaaatgcatc aagaagtgct ctttcttcta agatttctat
     9421 acttgcaaca tttccccatt cgttcatata aacaacatct tctacaccta gtctagtaga
     9481 ccccttatct gttacaactt gcatatcaga ttttgaataa ttttgcccag tttttgtagc
     9541 atttaatact ttagcattac ttacattttc tccatatcca atagctataa ttcctgttac
     9601 ctctttatct gaattaattc caagtttttc ttttaccttt tttccatctt caaaagtaac
     9661 ccaacaagaa ccaattccaa gttctgttac tttaaagatt atactttctc ctatgtaccc
     9721 tgaattttca atgtaattat cttttatgtc agataatatt ataatataac ttggagaatc
     9781 tatcatattt cctttgtacc ctgctacttt atctaaatta ttaaaaactt cacttctatt
     9841 cataattctt acatcaacat ctatttctgg aactagtttc ttacaagatt ctgagtattt
     9901 cttaatttca ctaagatatt cttctttaat atctgtgttc ttatattctc taacagactt
     9961 tctatttaat atgattgttt tataatccat aattttatcc tccccaaact agtattgtct
    10021 taattatata cccattaata tattatttta ctcatttatt taataaataa agattacaat
    10081 tttgtaatta ttatttatta ataatattcc acttttacat taataatgac cagttgtgca
    10141 aaatccattg ccaaccacca aataaaaaca tattataaag gtaatataaa ataacaaaca
    10201 aatcttaaca aaaaattaaa ctttttttac acgaaagaag gcttcccgtt gccttcttta
    10261 tttttataaa aaaataagct gtttctaaaa tgatttcaca tttttgaaac agccaagtta
    10321 ttctataatg acaactataa tttgaggatg tgagggagag ttgtcattat aaatttaggg
    10381 taattatatt atgttttaag ctagttcttt ctatatttat ataatacatt ttatatatga
    10441 attttatatg agattggtat aaatgatata tgaaattaca tatgtttata ttatattaaa
    10501 ttttattatt acattttcca caacaatact catatgtctc cacattattt ggaatattta
    10561 caaatacaaa ttctttacag ttctcacaat actttaatat agatatagtt ccacaagtgt
    10621 aacattcaaa tattacacaa tcctcatttt cctctactat ttcaaacttt ttactatgtt
    10681 caccacactc tgggcacttg tgattattta cattcataaa tactcctcct tattagtata
    10741 gttacatgtc aaaaacttaa ttaatgtatt ctatattact tattatatat tctataataa
    10801 atcatattct aatataataa aacaaattaa ataaaaaaaa accataaatt ttaaatttat
    10861 ggattaattc ttgtaatgat aactctattt gaggatgtga gggagggtta tcattacaat
    10921 agggtattat attatggttt ttaagctagt ctttctacac ctcatatgat acatatgcta
    10981 tatgaatttt atatgatttt tacataaata ttttatgaaa tttaaatttt ttagtcattt
    11041 tgaaatttgt aaaaagttct ctaaaaatcc acagcatcat aaacagccaa aatttaagta
    11101 aaacatcata aaaaaatttg tccaataatt ttaacaagta atctcacctc attataatta
    11161 ttgacacaaa cttaaataaa caatctataa atcttctata aatcttaaac tttcccccta
    11221 ttgatacaca atttctagtt tgtcaatttt attttgcatt tctaagaaaa tttcttcaac
    11281 agaattgtta aatatattgc ctaaatagat tcttttatct ttttgaaatg aataagattt
    11341 tacactacca tcagaagaaa tatataaatg actccactct gctccatatt ttgaaaacct
    11401 ctcctttgta tctttaaacc tcatatcttc tatttttatt gctttttctc tgtctcctct
    11461 tactacagtg tgaccccttt ttattaaact ggttattttt atatcttctt ttaatttaat
    11521 acgtgtatca tcattttttg aatatacttt ccatatcact ttatgacgat aattatctaa
    11581 ttcctttatt aagcttctat caatagtaaa actatcttta gttaccacaa ttaaatcaaa
    11641 atggtctaac atatattgaa atatttctct catactttta ttttttaaaa tatcctcacc
    11701 aataacctct ataaatctac agcctttctc atacatgcag ttcaataaac ttgtgatttc
    11761 agaaaaataa tcatttgtat tattatctcc atctatttct atagtaaagt acaaaggagt
    11821 aatgtatgat ttatttcctg ttatctcaaa tacacttgat agtgtctgta tatcatcttc
    11881 aaacgttaag tatacattct cataaaacat aaaaaattcc ataacttttt ctttcatatt
    11941 atggatattt ctatatctat tggataatat atttattata tcgtcagtag tatttttccc
    12001 atcacattca gccagtataa caatttgctt ccaacttaag ctatccacat ttccgatact
    12061 ttttttatat ccatcttctt catcataaat agggccaatt ataatgtttt cttttggcca
    12121 cagatgaacc ctagttccat cttttaattt cggatattta ttttttacag actcataaaa
    12181 tctacttgta tcacccatga ttctttacta ccccccatag tttaaatatt ctatgctaaa
    12241 aatagcactt tatttttatt aattcaacaa ttattcaaaa ttggtcatta tatatgttta
    12301 aatggattta acatcaacct tatttatatg ttattgatgt ttatatatgt tatataaaat
    12361 cttatttctc atacttcaat gtaatcttaa ctatctctgg tttacaatta agcctaatta
    12421 aaacttttga gcctcctaag cctttattta aaatcatagt gctattatct ttttcatatt
    12481 ttccccagtc atacttagga aagaactctc tatttggaga taatacacct ccaacaaaag
    12541 gtattcttat tatacctcca tgaacatgtc ctgctaaaac caaatctgct ccccattttg
    12601 catatttttc aaagaaaaat ggtgtatgtg ctaaaagaat gttatattca ttttcattaa
    12661 ctttacctag attgtcttct acaaaattgt cacttagttc taattttttg ttattagcaa
    12721 ataaatatgg atagcattcc aatggtataa ttaaaccata taaattaaga tggctattac
    12781 ctctatatat tcttacagat tcattttcca tatttattat tttctttgaa tatagttcct
    12841 taaaataatc cttatataga tgtttatact tttttattaa agatttttgt tcatgatttc
    12901 caattatatg atatacttca tatttttcaa ccaaattatc tattaaatct aatgcaactt
    12961 gaaaattttt attttctcca tctactaaat ctcctgttat aaatataaca tctgggttta
    13021 atgattcaat tttatctatc aataccttat tatttttatc aaacacctta ttatgtaaat
    13081 cactcacttg aactatttta aagttatcaa attcctttgg aatttttttg ttgaaaatag
    13141 tatattctgt cgtttctata tgctgagttt catacttata cagaatatac aataatatta
    13201 atactaatac tgtcattgaa acctttataa tcatattctc ttcctcttta ttctattttg
    13261 ttaatattat tataatgctt ttatgttttt tttaaaacaa taacatcatc acatacatat
    13321 aaatcttttc gacattataa aaataagtta tccttttcta aaattttcat ttattttaga
    13381 aaaggataac tataaaatta tctataaacc tctatattgt gaaatatagt ttttccttta
    13441 tttaaatttt tatatatatg ctctaaagtt ccatcaaacc taatagaatg tccagactct
    13501 aaaatataag ttttcccatc cacattaagg tcaagtttac cttctattac gagcacatat
    13561 tcttctaaaa catgactatg tgtagatgaa acatgagtac agttttcctc aagctcaatt
    13621 ataaaaagtt caaaccttct ttgagggcta aaagggtata ttggatataa cttcatgttc
    13681 cctttttgct caacaatagg ctctacttct tctttcttta taacctcata ggtatttgta
    13741 ctttcattta atagtgtagt aaaatttatt ttaaatccag atgaaatttt ccataaagta
    13801 gatactgtcg gacttgattc acctctctca atctgtccaa gcattgcttt actgacacct
    13861 gtcatctttg aagctttgtc taaacttatg cccatttctt gtctcaataa ccttaaattt
    13921 tctcccacat taggaaattt attatccatg ttaaaatcct cctgatagct atttgtattc
    13981 tatgattttt actcctgtaa gttctactat ctcttttaat tttaacatat gattgttaca
    14041 aatttcatca aattcatata tataatcttc aagccctaat gccttatatt tatcgattcc
    14101 aaatttatga tatggaagta actccatctt gcctcctgga acattttgtt taacaaataa
    14161 tgcagtattt cttatatttt cttcactatc atttactcca taaataattg gcactcttat
    14221 aaccatagat ttattcaact ttgaaagcct acatatatta tctaatataa ttttattact
    14281 tactcctgta tattctttat gaatattatc atccatagat tttatatcta caaatatgtg
    14341 gtctattttc tcaaatacat catttacctt attccaatca aaatatccac aagtttcaat
    14401 tgcaatattt atgcctttat cataaaaaat atcaactaat tctcttaaaa aatcaatctg
    14461 aagtgtaggt tcacctccag aaaaagttat ccctccatta gattcaaaga aaaatataaa
    14521 atctttttca acttcctcta ctatttcttc aacactcatt tcttcggtca ttatacaaat
    14581 ggcatcttta agacatacct tgatacactc tccacataaa tcacatttat tatttatttg
    14641 cgttctatca aatagtgaac ttatattttg aggacaaaca tctatacatc tattacaaga
    14701 tacacattta tctttcataa cacctaattt tactatgtta ctccaggaat ctggattaga
    14761 acaccactta cattttaatt tacatccttc taaaaatata gtagtcctta ttccatctcc
    14821 atcatttact gaaaaatgtt gtacttttac aactctacct tttttactca taatctacct
    14881 cataattaaa aattgctatg tgaatttcta gctattatag catcttgcat ttctcttgat
    14941 aaattaacaa attgagtact atatccagca accctcacta ataaatcttt atattcttct
    15001 ggattttctt gagcttttaa tagagtatca tttgatatcg tattaaattg tacatggaat
    15061 cctcctaaag caaaatatga tttaatcata gatgttagat ttctaagtcc tctttcagtt
    15121 tccaccaaat cttgattcag tcttaaattt agaagtgttc caccagtatg aacatcatga
    15181 tttatttttg atgcagattt cattgctgct agtggacttg ttgtatcagt accaacaaat
    15241 ggagaaactc cctctgtcaa aggttttgtc gcttttcttc cacaaggagt tgcacctact
    15301 atttttccag ttggtacata gtttgatata cccataaatg cactattaaa tttagagcca
    15361 aaaatatcct tgtattttct agtttcagta taataaaaat cagaaacttc aattgctaat
    15421 gaatctacat aatcattatc atttccatac ttaggaacat ccaacgcaag ttttcttaat
    15481 tcttcataac cttcccaatc attatttagt gcttttgtta attcttctaa cgtagtcacc
    15541 ttatcctcaa atactaattt ttttatagct gccaatgaat ttgaaactac acctaaccct
    15601 ataccagtta atacaggacc tatattatat tttgctcctc ctttacttaa atcaactccc
    15661 ttatccaaac atccatctac acaagtagat aaaaatggtc ttggtaccat ttctttatga
    15721 atttgttgag caacagtagt tcctataaca gaacttttta caagatatgc taattgcttt
    15781 aaaaactcat ccttaagttc ttcaaaagaa gtaaattctg tgatattttt tgtatctaac
    15841 cccatttttt ctccagttaa tctactctta ccttcattca tagcatattc taaagctgct
    15901 gcaaaattga tatttacggc tgaagtccac tgtcctgttt ttctaaaatg aggaactaca
    15961 caaccacagt tactccaatc tctagcatct tctgcatcat atccatcttg taataacatt
    16021 tgtgcccctg cactatcgct gtgtatagca gggaaaccag ttccttgttt taccaattta
    16081 gcaactgcca ttacgaaatt gtctggtgct ccttgactca ctctaacact taatcctggt
    16141 tggtgagttt ttacactttc tgtagccttt aaacacatat atgagatatc attcgttcca
    16201 tcagtaccat ttctcttttt accaccaaca gtaagatttt ggaattgatt atatcctgca
    16261 aagtaatttg ctgtatttgc tgatatagtc catacccatt ctgataactt aatccaaagt
    16321 gcttctatca attcttgagc ttctgattca gttattttac cttctctagc atcattttca
    16381 taatatggat acatatattg atcaaatcta cctaaattta atgccaatgg attttctgat
    16441 agaataccac ctaattgaac aaaccataca aattgtattg cttcataaaa attagttgga
    16501 gggtttgctg gtacattcat acatatctct gaaattttta taagttctaa ctttctcttt
    16561 tcatctgttt cttgcttact catctctttt gcaagatttg aatatctttg tgccaatgtc
    16621 ataataccct gtgcaactat agaaacagat ttgtaaaaat ctatcttttc aatattttct
    16681 gaaactgata tatctaattc tttaattttt ttatctgcat cttccttaat ccctttatat
    16741 ccttttacaa acaatatatc ttgataatct ggtgttactt caccaactgc ctgtctccac
    16801 ttagaatcat tatctattat tcctgtatct actaatatct tagctgtatc ttctgggatt
    16861 cttgctaaga aaacttcttc caaagatttt cccttccaat atggaaatat ttcttttctt
    16921 ataaattcta tttgttcttt tgatattaca tatgggtctt gagttctttt atcaaaagta
    16981 tccatttctt tgtctaccca ttgccaagaa aactctggtg tcaatatccc tgttcttcta
    17041 aattttcctg ctgtacctac tattaattca ttttcaaaga tttttatagg aagttcttta
    17101 catgtctcca aaaaagcttt agctcttctt atacagatag cttctccctc agttttttta
    17161 tgtgattctg taaaaattct agccctttca caacatatca taggtttaga attaatatat
    17221 tcttgtctaa atgcttctat tctattagtt tgactcattt aaaatccccc tttggataat
    17281 atatactaca tttttgtatg ttataacata ctttaattat attatactgt cctttagcat
    17341 aaaatggaag caaaataact tatttttttt catctacctt gaacacctat atattaatac
    17401 tttttttgtt aaatttataa aatctaaaaa aattttctat gatatatttt ctatattgtt
    17461 atagttatgt ctaatatact aatgatttga aatatcaaat ttgtatacta gacttagttt
    17521 taaaacctta gttgattgtt taactttgtt aacttcaaca tgtatatcct tcatataagg
    17581 aagctctaca acacctactc ccttattaaa gtcttcttca accatagaaa aaatttcttt
    17641 ctcagttaag ttcgtatcag tcaatgattt aaataaattg tatataaatt taacatattt
    17701 atcactctca gataacttat catcttctgg atactcttta gcacagagaa tatctattgt
    17761 tacttttcct tctttatcgt cttcagacat agaatagaat aaacttcgaa tatttttttc
    17821 aggtggtttt tcagcaccat ttatagatac tacaaagcta ccatctgatt ttgagttagt
    17881 aatactataa ccactgtcta ttatagcttt cgaaaatctt tgagataaat ctttttttac
    17941 ttcttctcta cctttcgcat cattaatctt ttgtgagtaa ttattaaata gctcaataga
    18001 ttcatctttt ttatcttcaa cttgttcttt caatgaatct ttactaattt gttctgagct
    18061 acttaagttc ttatcagata caggagacat acaccctacc atcaatgcta agctaagatt
    18121 taaagccaca attattgcca ctctatttat attccttttt actttcatac acaatcctcc
    18181 catcacacta accgctctaa agtattattc attgcactag aatatattta tattttcttt
    18241 atattaaaga tttattattc aatacatatc accttcctat ccaattctta taacttacta
    18301 ttagtaaaat tataagctcc ttaatacaga aataaggatg ttatcttttg ttattaaaag
    18361 ataacatcct tatttttttg tatcaataca tatgtcccaa ctggtaactt aatcgcccca
    18421 actgtcagta tcttggtcca atggtatata tatatttagt ataaatttat cgatactatt
    18481 ttcaaataat aattctccat tatatttttg taaagaagat ttaatactct gaatacctat
    18541 tccatgtacg aacttatcca ttttgtttgt taacaatata tttttattaa aagtaagctg
    18601 atttagttta ctattttcac atttaagtac aaaaaatgac cttgttatag ttcctttaat
    18661 tctaatatat ttattaatat tttcatccac tattttatca catgcttcta ttgcattatc
    18721 caaaatatta gaaaatatgc ttgacacatc tataggtttt acaaaattta cttttgaaaa
    18781 atttatagag caagtaaatt taattccttt ttttaaacat acttcactct tttcgttgat
    18841 tataatgtct aatatcatat ttcctgtatt atagatatat ttaaatgttt ttatttcatc
    18901 ttttaaattg ttaacatatt cattaatttc tttgctattg tttctaaggt tgtctataca
    18961 ataaatgtga ttatttatat cgtgatatag tttcttaact cgcatatgag attcttgaat
    19021 acttaaataa tgcgcatatt gcatatctaa cttatttttt attaattcag cttgagattt
    19081 taatctattc tcttttatta tttctttaaa caatagtata agaaatatac tactagctcc
    19141 taccaatttt ggattaacaa aattatcaaa atagtatcct tctgaatgta atgacccaaa
    19201 ccgttctaat ttttttaata cataatttac aagcatattc attgtattaa ctaataaggc
    19261 aaataataaa tatacataat ttctcttatc ttggctaatt aattttatag actttctaaa
    19321 aaagctaaat ataagatata taagaataat tattaaatta ctatatatct gaatttttat
    19381 agattctaag taaggtacta ataaagattc tttagatgaa ataacattac ctgtaattgc
    19441 aaaaaatagt attctatata taacagcatc caaacattta taatatacac taaatagata
    19501 aaagaaaatg gaatacttaa tataacccat cttataaaaa taattatagt atcctcccca
    19561 agcaataaat gctaatatat aaaataaata gtttatatta ctaaagtaat ttcctccatt
    19621 aaataatcta cttatctgaa ttataatata aataagaaac aagacaatat agaatactat
    19681 tttttcattt tttttactat cctttttata aattaaaatt ccgttcatta tagaaaactg
    19741 tataaatata gataaaacta ctaatagctc agtcataaag tttagcatat tgtatcacca
    19801 agaaatttta agaatttctc cttaacttct ttatatctat atctactaat aggtacctct
    19861 tctccacttt ccagtattgc agtattaggc tttatatttt caacatatct taaatttact
    19921 ataaaacttt tatggcatct tataaattta tatggattta attctttttc tattttgcct
    19981 aaactatatt ttatatcaaa attcttgttt attgtgtgta ttagcatatc ttttttttga
    20041 acttctatat attttatttc atttaaataa atcttatatg tattagactt attttttatt
    20101 gtaatatgac tttccttatt tatttcaata tctttgatac aagttagcac atgttttttt
    20161 agttcttcca actctattgg ctttagtaaa tacctataag ctcttacctc ataaccttct
    20221 tgcacataat ctattaatga agttacaaat attatttcca tttcattgtc tacttctcta
    20281 atctttcttg cagtatccat tccatttagt ttttccattt ttatatcaag aagtaatata
    20341 tctatatctt ttaaattact ttccagtaac tcttctccag atatatactt ttgtatctca
    20401 tattctatac ttatatcttt taatatattc tcaaggtaat cttctattaa aagttgtgtt
    20461 tctttttcat cttcacaaac tgctatctta atcataaaat gcctccttac ataatttcta
    20521 gttaatacaa ttaaaatatt tataatatat ttaaagataa ttttgtatat ctgatacttt
    20581 aggataacat tttcaaatta tttttatcaa tactcaatcc catataacta ttctttgata
    20641 tttcaattta aagacagaga ttactataat taaaaacagt actttattaa caaaagaaga
    20701 tgtcttaaaa tattaaaaaa ataattttag gacaccttct tttatttatt taaacttttt
    20761 aagccttaaa taatacatta atctcctata taattgtact gcatataaaa tcaacaatat
    20821 aatctgtagt acaatagcag ttacagatgc tccataacca ctatataaat ttcttatttc
    20881 aatattcaat aaatatataa atattactac taacataaag aatataaaca tattcataaa
    20941 taaaattgac tttactttat ttgttttatc agaatcacta tataatttag gaggtatgtc
    21001 tttgtattct ttcgaccata tataccatgc agatgtaccc ataaaactac caatactcct
    21061 aaatacaaga ttccagccat ttgatttatg ttcatcaaaa taattattct ctacatcata
    21121 gtagtaatca acagtgtatt ttatttttct tggacttccc ttatgaaaat aaaatattcc
    21181 tccaaattta tttatcttat ataaattata tcctttagct tcaatatctt ctaaccattt
    21241 ctctatctta tcaggtgaac tataccagtc aaatttgaat tttattttct tttccatagc
    21301 actcattctc caaaatgata tttttaaata gcttaaaaat ctatttaaat aattatatca
    21361 ttttgatact aattttaggt tacaatcata tatttaaaag ctatttaaat agtaataaac
    21421 taatagccat aacacccatt cctgcaatca atccataaat agataaatga tgttccccgt
    21481 actctctagc tgatggcaat aattcatcta gtgatatgaa taccataatt cctcctacaa
    21541 ttgcaaatac aattccaaga gttatatcat ttaaaaaatt tctaagaagt acatatccaa
    21601 taatcgctcc taaaggctca gacataccag ataaaaagga ataataaaaa gctttctttt
    21661 tatctcctgt ggcataataa actggtacag atacagatat accttctggt atattgtgta
    21721 ttgcaattgc aattgctatc ggaatagcta ttgtaacatc atcaagagct gatataaatg
    21781 tagctaatcc ttcaggaaaa ttgtgaattg ctatagccat tgctgtaaat atacctgttc
    21841 ttaaaagaga cttatttttt ttgatattct tttcttctat attctccatt ttctttattt
    21901 catgtggatt ttcttcttgt ggaattagct tatcaataac agcaatgata gccataccta
    21961 taaaaaaagc tattacagtt gaccaacttc ctaatttctc tcccatagat tttgtcaaag
    22021 catcttgtgc tttaggaaaa atttctatca tagaaacata aatcataaca ccagcagaaa
    22081 atcctaagct tatagaaaga aacttagtat ttgttttttt agcaaaaaat gctatacaac
    22141 ttcctatacc agtagataaa ccagccaata atgttatcaa aaatgcaaat attacattat
    22201 tcaaataaat caccttcttt ttaattgata ttgattatca ttttctttat gctatcatat
    22261 atattttata tagtcaatat ttataaaaaa tatacacaat aaaaaagcag agatataaac
    22321 ttagtctctg ctttttcttt atagtatatt aaaattattt atttaagaaa tccactgcat
    22381 attgcacata taaagcagtt ccaatttcta gagcatcttc atctatatta aagcatccat
    22441 gatgatgagg ataacaagca ccttttgact catttctagc tcctacaaat gctagtgcac
    22501 caggtgctat attcataaac tcagctaaat cttctgctcc tgttactttt tcaaatagtg
    22561 ttatacagtc ttctccaaat agcttaattg ctgcatctgt agctatcttt gaacattctt
    22621 tgtcatttat aactgctggt gttaagtacc catactctaa ttcagcatct gctctatatg
    22681 cttctgctgt agattttgct atacgttcta aaattccagg aatttgcttt ctaagctctg
    22741 gattaaatag ccttattgta ccttctaaga tagcttcact cgcaattaca ttaaatctag
    22801 ttccagaatt taaaactcca acactcacaa ctaatggttc cagaggactt acttctctac
    22861 taaccataga ttgtagattc ataactattg ctgaacttgc aagcactgca tcaacacctt
    22921 gatgaggaag tgaaccatga ccacctctac cttttacagt aattttaaag aaatcagcag
    22981 aagccattct tggtccttct tctaccgata tggtcccaga ttctacatca gtccaaagat
    23041 gtattccaaa cacactatct acaccttcca tagcaccatc ttgaatcata gctcttgcac
    23101 ctttaccaac ttcttctcct ggctgaaaaa ataattttac agttccattg atactatcct
    23161 taatatcatt taacactttt gctgccccta gaagcattga tgtgtgacca tcatgaccac
    23221 aagcatgcat aagtccttca tttttagatt tgtattctac atcagtgcat tcaacaactt
    23281 gtagagcatc catatcaccc ctaagtgcta cagtctttcc tggattagct ccttttatag
    23341 ttgcaattac acctgtacct ccagctgata catatggtat ccctatttta tcaagttctt
    23401 ctttaactct ctttgatgtt ctaacttctt ccatactttt ctcaggattt tcatgaaatt
    23461 cccttctaag cttaattaca tagtctttat aactctttgt tatttcttta atatccattc
    23521 catacctcca agtagtacac attcttctta tttaaaatac tttttatcac tcaaatacta
    23581 tattagattt acaaagatac ccgctattac tacagaagct attgtaactg tagtaaatcc
    23641 tccaacaagc atctttggaa gcatcttatc cattaaaaat tctttttctt ctggtgtttc
    23701 agccaaagcc tttactgcct cttcagttaa tatatagttt ggtggaaaac cataaagtga
    23761 tgtaagcgaa actgaaaaag ccatttcttt actttcacct aaaagcttac ctactataat
    23821 agagaatatt cccataccta ttacaccaaa tattatgatt cctacaagag gaactgccat
    23881 ttcaacaagc attgctggtg tagcttttgc taaccctgca aatataaaag ccatcaatga
    23941 tgtcattaac catccaaatg aaccagattt attaagtggt tttctatcaa ctattccaag
    24001 ttctgatgct attacaccaa atattaaaca tataacatat cttgatacaa cttcatttgt
    24061 aagatttgta aattgtactg ctaaccatgc tacaaatcct aatctaagta ttatcatata
    24121 tgtcgtatca tatttttctg gtaagtctgg aattatctta aatctgcttt tttgttcagg
    24181 taaatcctta actttttctt catctgtatt tacagttact tttccacttc taaagtctga
    24241 taaaagtctt tttccttctt ttttaagcat taatgctgta ataggataac ccgcaaatcc
    24301 ttgtgcaaca tacatcaaaa ttgcaagtac tgataaactt gcaagacctt ttgctgtagc
    24361 agcatctgcc atcattatag atgcaactag ccctccagta agaggaggtg tagctattac
    24421 tgctgtatcc catccaaata ctactgtccc taatgccaaa gcacctacac atattcctac
    24481 tattcctgcc aaggctatta ctattgtttt ccattgacct gctaattcct taatactcat
    24541 catagttccc atatgagtta ttaacaaaag catacctaat tgagctaatg gtgttcctaa
    24601 agcggctaag tccacaatat tttctgggaa aaaagtccaa aatcctacta taaatataat
    24661 tgctgataca aaaaccgacg gaacaaaagc tttagttttt gctgaaacta tatctcctat
    24721 cgtcagtgat actaaaacta gacaaaaagc tgttattgcc tccatacaaa atcccccctc
    24781 ataataaata tatttttata aaatgtatgt atagttatcc attattttac tacttttgaa
    24841 aaacatttca agtcaaaatt cgattttttt cataaaattc gataaattcc ataaattaaa
    24901 gttagttttc taaattattc tttttgtaaa aacgttatcc cgaccattgg ctatttaact
    24961 ctattcttac aaagagaatt aaatgtaatt tgcaaaaaat aaaacatagg atacatttta
    25021 ttcataaaac atcttataaa tataaaatga attgtcttta tgaatcttaa tatatcctat
    25081 gtttgtaagt ttaatgtgta tgttagctat ggtgtaaaat ttgtatacta gttattgtgt
    25141 aacctactat atactccatt tttgtttact agctcttcat gagtacctct ttcttcaatt
    25201 cctttatctg tcaatactat gatttcatca gcatttttta tagtagtcaa tctatgtgca
    25261 acaactaaat ttgttctatc tttacttaat tcctctaaag actcttgaat ttctctttct
    25321 gttacattgt ctaaagcaga tgtagcctca tccaatatta ttattggagg attctttaaa
    25381 aagattcttg aaattgaaat tctttgtttt tgcccacctg ataattttac gcctctttct
    25441 cctatataag tatcatatcc atctggcaaa gtctctacaa agtcatgtat tctagctttt
    25501 ttagcagcag ctatcatttc ttcatctgta gcattagggt tcccacaaag aatattatct
    25561 cttatagttc ctgtaaataa aaatacatct tgttgaacta tacctatatt ttttctcaat
    25621 gattttaaac taacatcttt tatactcttt ccatcaattt ttatatcacc cttatcaaat
    25681 tcataaaatc ttggcaatag attacataat gtagtctttc ctcctccaga aggtccaact
    25741 aatgctatag tcttaccagc ttttatagat aaacttaaat tatccaaaac ttgagtctta
    25801 tcttcatatg tgaaagatat attttctatc tcaatgtcac cttttacatt ttcaagttca
    25861 ataggatttt tagcttcttt ttgatggtct tgttccatta tctctatgaa tcttttaaaa
    25921 cctgtcatac cattttgata ttgctctgta aagtttatta attttttcat aggttgtata
    25981 aacattttta catatagtat ataagcagca aaatcaccca aagtaatctt tcctatataa
    26041 gtaaaataac caccagctat tacaactacc cactctaaga tatccatgta taaattcata
    26101 ccagagtaat attctgccat taccttataa gaatcttgtc ttgctcttct aaataattta
    26161 ttgcttctta caaacttatt taactcttct ttctcagtac aaaaagactt agttaccttc
    26221 atacctgcta tactattttc taaagtagca tttacatcac ctatagtaac tctactcttc
    26281 ataaaagcaa tattcatctt atctttttta gctattgcaa accaaattat aaacggtaat
    26341 atagcaaata ttataagcgt aagaggaata tttatatcta taagtataaa gaatgaacca
    26401 accaacatta ctatagaaat gaataaatct tcaggcccat gatgtgcaag ttctgttata
    26461 tccattaaat catttactat tctagacata gttactccag atttgttatt atcaaaatac
    26521 gtatttggaa gtctttgtaa gtgtgtaaat acctcatttc tcatatcagc ttgcatatct
    26581 acaccaataa catgtcccca atactgcata aaatagttaa gccctgcttt tgctataaat
    26641 ataagtataa gtgctactgc aaaaactact aacattctta agtttttatt tggaacaacg
    26701 tcatccatta tatttctagt tatcatagga taaactaaat cacataagga aaatagaaaa
    26761 gctgctataa ggtctagtgt aaaaattttc ttatatggct tataatattt gacaaattgt
    26821 tttatcataa gtattaaatc cctcctttat tagtacttct attagtactt ctaaaaaata
    26881 cccataaatt agtataacat aacaataact ttaaatcttt tataaactta caaagtaata
    26941 acaatctttt tcataaaatt gaagatttat atcatatagt tgtatacttg aaacaacata
    27001 aaaagagcta tatctctata tttaaaattt tataaagata caactctata tttaatacta
    27061 aatttttttt ataaatacaa aactacttca atgcatttaa tatcttttta tctaatgctg
    27121 ttgtatttat acctgttata tatcctgttg cctttattgt aggtatatca taagttgttg
    27181 gtagtatagt agtagatacg attaaatcag caccttcttg ttttgttgaa cattcagcaa
    27241 ttttacattg ctcaacttct gcttgtatat tattttcttt aaccaatctt tctactctgt
    27301 cacaaactat tgttgatgtt gcgattcctg ctccacaggc tactaatatt tttttcatat
    27361 attgtcctcc tacaatttct ttaatatttt ataactcaaa ataaaattga taaatttctt
    27421 atatctttat ttatataaat aattatatca ttttatataa gaagaacatc ttaaaattat
    27481 tcttttaata tgttttttat ttcaacatta cttatactta aaatttcatt ttttatacaa
    27541 gactctatgt actttgatat atttttataa tcatttaaat taaactgttc aatattcaat
    27601 ttatattcta tatcactgac aatacctatc aaatcagact tattagataa aatatcctca
    27661 tacttacctt ttctagttac ttccaatctt ttaaatctat aatttttata tccttctatg
    27721 ataatcaagt ccatatcttc atataattga atcattttat ataatggatt cttctctttt
    27781 agttcttcaa tatatgctac tcgtttatct gatattatac agacttttct cgccccagat
    27841 tttctatgtt tataagtatc ttttccttcc tcatccatat caaaatcatg acaggtatgt
    27901 ttaataactc caacacgata ccctttttta tttaattctt ttattatgcc ttcaatcaac
    27961 gtagttttac ctactcctga atatgagaca actgacaata tattatacat aaaattgtgt
    28021 cctttcataa aactatctaa taacaacatc cactaattga ttttctttta ttgtctcatt
    28081 ctttttaatc ttaatcatac aattacttct tagagttgca gatagtctag cttttgcatc
    28141 tttcttatca tttagctcta catacaattt accttcactt gtatatagtt ttccacttac
    28201 aaatctatct ttatttgaaa gtttattaaa ttctccttta aatatagctt ttatatgatg
    28261 tgttcccttc ttatatgtta aatactcaat aacaggaact atcacattat caaataccac
    28321 tattgctgca tgtggattac cagaaagacc aaataatagc ttttctccca atgtacctac
    28381 ataacaagct ccaccaggtt taatgtttat cttccaaaat aattctgttg cccctatttt
    28441 tttgaataca tctggaatta aatctttatc tccaacagaa acaccacctg tggtaattaa
    28501 aaaatctaca ctctgtaaca tattctttac ctttttttct aaatccaata tatcatcaga
    28561 acaattgcat attgtatctg cttgtattcc aagttttaat aatcttgaat ataaggtata
    28621 tctattacta tcgtatattt taccattctc taaagtctca tttatatctt gtagttctgt
    28681 acctgtattc aaaattccaa cttttaaatc atcataaaca gttactttgg atattccaag
    28741 acttgctaat actccaatac catcatatcc tatattctga tttttattaa taatcaattg
    28801 cccctttttt atatcctcac ccttaaatat gtaattatcg tattccttta attttatatt
    28861 taaagttatc atatcaccta taactgttac atcttctttt tttattacac aatttgcacc
    28921 ctgtggtatc tttccaccag tcattatctt cactgcttca tttttattta ataccctatt
    28981 aaatacatct cctgcataca aagtccctat aacctttaaa tttctatttt cagaatttgc
    29041 attatatgca taaccatcat agggtgacct atcaaatgga ggactatcaa ttgttgaata
    29101 tatatcttct gcaactacct tatttactgc atctataaga tttactatct tgaccctgtt
    29161 tattggtaaa acattttttt caataatttt tatggcatct tctaattcta tcattttaaa
    29221 tactccccaa tatatttttt atttaagata tttctatgta atatattata gattataaaa
    29281 gttggaaata cttttatctt atatttaatt ataactaata gttatctata agtgcagttc
    29341 aaattttata aatctaataa aaaaactgtt cccagctaga aatttccttc tatcttgaaa
    29401 cagcatcata tgctttagaa tattttattc taataaagtt ccttttatta tttttacaat
    29461 tttatcactt tcaatagttt ttatagattt tattttgtta tccacaatac ttattgtaag
    29521 tacctctttt tttaatattt tgttatcttc tttcaatcta taactcttaa ctactttact
    29581 gccttcatga ttatatgctg ttaaatcata attcgcatct cctacaattt catttattct
    29641 ggaatcttca acaccaacat actctcccag gtcaatatgt ctaaaatttt ctagtgatac
    29701 agccgatttt tcatggtcac ttttttcaat cactatacta gattcagcat caatgactga
    29761 tataccttgt gatgagaaag aattggtttc aacattgaca actttatttt cgttaatatc
    29821 aacatataaa gcacttccat ctagttcatc atttccagta tattttggat aaactaatgt
    29881 catataactt gatgtattta tatcttgcat tgtatttgat tcttttaaaa ctttaggttt
    29941 tatataataa aatgtattat aaggtatacc catattcttt ataatgtact tataatcttt
    30001 attcataatt tcattaacat cattttgaac ttttgtcata gttttttgct gtgttgcttt
    30061 acttgctact tgatttttct ctttagtatt ttctttatga catccaacaa gtataatacc
    30121 taaaatagtt acacaaacta atgacctttt taacttcata aatcaatcct cctttcttaa
    30181 attttatagt atttatctat atctcaattt acagttatct cttttttcaa taattatatt
    30241 tattatatta taaaataatt atataatatt tatttgaatt taataagatt aagaagctaa
    30301 ttgtaatttt tctgtaataa aaaacacttt aaagttgaat tttgaaaatt caatttacga
    30361 tatttttatt gtaagtacct tacaacatta taccaaatta ttcctaaaca atcaaaaact
    30421 ccatgaatat ttaaaggttt tctattttaa aaatcacctt tgactattaa tttatcaaat
    30481 atgttataat agttttagat aatttaagga ggattaaata atggatttta aacaacttga
    30541 agtatttgtt gctgttgcaa aacatcagag tttttcaaag gctgcaagag aacttttttt
    30601 aactcaacct actgtaagcg cacacataca gaatttagag agagagctag aaactgttct
    30661 tataaataga agcaacaaag ttattacact cacaaaatct ggtgaaattc tttacgaaca
    30721 tgctatatat atattgaata attgcaaacg tgcaatttat gatataaaag aatattcagg
    30781 aaaaatagaa ggtattatag atatagcatg tagttccata cctgaaactt atattttacc
    30841 tgattttatg aagagttttt ctatgagtta tccagatgta aaattttcca taagccatta
    30901 tgattctcaa tatgctatat cagaaatttt aaatgaacga ataagctttg gattagttgg
    30961 ttctaaaatc aataatcctc aaatagagta cctagactta ttagatgatg aacttgttct
    31021 tatcactcct tcagatttta aaattgataa taaaaataat tgtatcgata taggagaatt
    31081 ggcttatcta aattttatta tgagaaaaga agggtcaggt acaagaaact taatactaaa
    31141 cacacttagt aaaaataact ttccagtaag taaattaaat gtaatcgctc atgtagaatc
    31201 aaatgaggct attaaggaaa tggttagatt aggtcttgga gtgtccttta tatcgtacat
    31261 ttcagctatc gattatctca atgcaggtaa aataaaatgt tataaaataa aggatgttga
    31321 ttttactaga aagtttttct tcatttactc taaaaagaaa actttttccc cattagaaga
    31381 taaatttcta aacagattat gtgagtattt cgaaattata atataataac tttaataaag
    31441 tagtgcttaa ttttgagttt ataactaatt aataagctaa ttataactat cacataaatg
    31501 cttataaatt attatgaacc atctttcttt tttatttaat ttagtcaaaa aatccctcgt
    31561 tcaaatgaac ttgggatttt tttatttata ctactccaat agcagccaat actatacaaa
    31621 taatcataac tgaaattaat atcgtagttg tctttacctt ttttcctaat aaccaataca
    31681 taataccgaa tatcatagct ggaagcatac atggcattat ttggtctaag taagtttgaa
    31741 taggctctgc ccattctcca ctacctacat taacactaag ttttaacatt acattagatg
    31801 cagtcatacc tccaattacc ataagcccta acattgaagc tgcttccata acttttgaaa
    31861 ctatacttga accactcaca tctttaaaga attgagttcc atacttaaat cctttatcta
    31921 gacatatata gcgtataata aaatgaggaa catttattat taaaaggaat aaaatcggtc
    31981 ccattatgtt accctgagaa gctaaagcta taccaacccc agctgctata agctttaatg
    32041 ttccccagaa aaattaatct cctatcccag aaactggacc cattaaactt gatttaacag
    32101 catttatact attagcatca aattctttat tctttgcatt ttcttcttcc atagctccag
    32161 atatacctac caaaagagta cttatatgag gagtaactga cataaattct aaatgtcttt
    32221 ttaaagcctt agatttcttt tctttatcat ctttatataa tctacggatt attggtgcca
    32281 tcatgtatgc atatgctata ttttgcatac gttcgtagtt ccaagatgaa tctaatgtca
    32341 atgaccttct aaaacatttc caaaagtctt tcctcgttat tttactatct ggtgaaattg
    32401 tctctaactt cttagaactc gttgtcatct actattacct ccttctctcc tacaaagtta
    32461 acatatatta aagctattgc taatccaaac aatgcaactc ctgttactgt tatgtttagg
    32521 taagcaacca atataaatcc taataataaa aatgctactg ttttcttatt aagcatcatt
    32581 ctagctaaca tggcaaaacc tattgctgga atcacgcctg ctgcaacatc cattccatga
    32641 gttacatatg atggtataaa tgaaagtatt ttttctatta ctggaacacc taatgaaaat
    32701 cctataccta ctattattgc taatattaat ttatttccta taccaaataa taattgcaca
    32761 cgttctacgc cttcaatatt cccctcttct gcataacggt cagcaatatg agctccccat
    32821 gtaagtacta ctgtcattaa gaagttatct ataagcaata ctagagttgc tataggaact
    32881 gcaagtacaa ctgctgctga tacatcttga cccgttaata ttacaaacgc tgtggcaata
    32941 atagaaccag acacaaaatc aggaggatta cttgccccaa caggaaatgc acccataaat
    33001 actaattcta atgttgaacc tattactata cctgtatgaa gattacctag tgctaaacca
    33061 acaagtggtg caacaactat aggtctatta tgcattgtag aacctacaaa actatgcata
    33121 tatgcaaaga atgcaattag agttatcaaa ataacttgtg taaattccat tttcatcccc
    33181 ctaaaattat attaatttca ttacatttgt agcatcatca tcaggaacta attgtacaaa
    33241 tacatttacg ccttctgaat ctaactcttt aatcatcttt atatcatctt ttgatacatg
    33301 cactgcttta gatatatttt cacgattatc atctgatttt gttccaccaa ggtttataga
    33361 tttaatagct tttacctctt tagcaagtct ataaacatct tctacagatt cacaaagtat
    33421 caataagttg tatttatcag taacacctga gttaagtgct tttatagaat ctgctatgct
    33481 tttcattact aacttaacat tagatggttt agccatttta agtcctgcca ttctcaattc
    33541 atcttttaat aagtcatcac ttgctatcaa tatacagtct gtacttaaaa actttgtcca
    33601 tgtaaatgct acttgtccat gtataagtct gtggtctact cttactaatt taatcattat
    33661 aattcctccc taattttttt gatttcatcc atgaatgttt ttacgtgttc tacactaaca
    33721 tccccaaaat ctttgtaatt atctttaaag taacttccta ttattgccat atctcctaat
    33781 ttaagctgtt tttttgcatt ttccaatgta actccagcag ctataaccaa tgggaagtct
    33841 cctaaatttt tacgaaacag ttctattttt tccattgatg tttcttgacc tgtagcattt
    33901 tctgtaactg ctatagcatc acatcttgtc attcctattt ttaaatcttc ttcaacatca
    33961 ttttctgata atactggctg atatttaaaa cgtacgcctc caattaaata cgctgggcat
    34021 tttgaacgtt gtaatttaaa aaactcttct aaagtagctt catctctagg tttaacatga
    34081 cctactacag aatcaacctg tatataacta gcattatatt ttgttgccag ttcaaatccc
    34141 atagtatcaa catttaaaca gtttactcca tatggtattg ataaattagc ttttgataca
    34201 tattcaagta ttctttctaa atcataataa ttaccatagt aattttctaa cattattcca
    34261 tctacaccat tttcttcaaa gattgtaatc tcttttttag ctctttcaaa gatatcttct
    34321 ggagtatctc cttttaagtg tatcattgct ataattggtt ttttactttt aaatactgat
    34381 aatattccct tttttttcat aaactaaaat acctcttctt cttctttaat ttgtaatgtc
    34441 acgctttgta ttcctcttct agattcttcc actaattggt ctatatcttc aactgttaat
    34501 tcatcagaaa accttgtaag aagttctaat accatattca aattcattcc agaaaataac
    34561 ctaacattat gtagattagt taatcttaac attgctgtac atacacttgc tccatataag
    34621 tcagataaaa ttatatattc acattcttta tcttctgata ttgttttttc taattctaaa
    34681 gcaaaatctg aagcactttg tccagggtac aaaccatacg aactgacaca atctgctaaa
    34741 tctcctacta tcatttttac tgcatttaaa agcccttttg aaaagtctcc atgagatgct
    34801 aatattatct ttttcatact catcctccta ctaaattata gattatattt ctgctgatac
    34861 tgcatatttg tacttatcac ttcttataaa ttgctcattg taatataaga catcattatt
    34921 ttctgtgtac accgattgtc ttactttcaa tagtggcata ttacttgcac atttaagatg
    34981 gtcagaatat tctttgtttg aatgttttac ttcaaatata ttttctactc gtttaggtaa
    35041 tgtgcttata ttattagata taacctccat taaagattta tcttctaatt cttcttttaa
    35101 taaaaacatg taatctattc taaaatagtc aacttcaaaa ataacaggta cttcatctat
    35161 taatctaagt cttttaatac atattacctt ctcttctagt tcaatactta aagcttcagc
    35221 tacttgctta tctgcttttt ttattaaaac agagattatt ttggtacttg gttttgcatt
    35281 aatacgatga caagaattag taaaactatt tcctgcacat gttgcttcta ttctctctgg
    35341 tattgttaca taagtccctt taccacgttt tttacataat atatcttctt ttacaagttc
    35401 attaagtgca tttctcacag ttatacgact tatattaaat tctttacata agtctccttc
    35461 agatggaagt ttatctcctg gtttatatat gccagatgct atttgttttt ttatgttgtc
    35521 atatagttgt tgatataaag gaacaaagga atttacttct aaatccattt cttttttttg
    35581 tctcttttca tccattttgc tcacctccct atgtaacatt tttataacat tatataacaa
    35641 gttctttatt acatattata acaagatgaa atcgttgtca attttttttt aaataatttt
    35701 taatttgaca gtattttctt ttattttctc tagtgtgaca aattgctatt tttacataaa
    35761 aataagactg ttgtacaaca gattaaattg tttatacaac agcctttatt cacttattac
    35821 atttatattt ttacttataa atttatatta aaaaatgcct tatatccctt atacatttca
    35881 tatatgtcta ctttagagac aatctcatgt ggtgcatgca tatttaaaac tccaacacca
    35941 cagtctataa cctctgcacc ttgatttgcc aatatatggg ctatagttcc gcctcctcct
    36001 tggtctactt ttccaagttc agcagtttgc catactacat ttcctttatt aaaaattctc
    36061 tttacttctg acataaattc agcattagca tcattacatc cactctttcc tcttgaacct
    36121 gtatacttag ttaaaactac tccatttccc atatatgccg aatttctctt ttcatatgct
    36181 tctccaaaat ttgggtcata tccagcagaa acatcagctg ataatacctt actatttgct
    36241 aaagctcttc ttactttaat atcacaataa tctccttcta aagcaatcag ttcagccaca
    36301 gtattttcaa aaaactttga gtgcatacct gtattccctt tagaaccaat ttcttcttta
    36361 tctacacata atgcaactga agtaaattct ggttgttcag tttctagtat agcttttaca
    36421 gcagcatatg aacataccct atcatcatgc ccatatccca acaccataga cctatcaagc
    36481 cctaaatctc tagccttacc agctggaact acttcaattt cagcacttaa taaatcttct
    36541 tcaactatat tgtatttctc atttaaaatc tttaatatat ttgctgttat aggttctttt
    36601 tcttcatctt ctaaaggcat attcccaatt aatatattta aagcttctcc actaattcct
    36661 tctgatagtt tcttttgcat ttggtctcca gccaaatgaa tcaataaatc agttacacaa
    36721 aatactgggt cactatcttc ttccccaata gatatgtcca cttttgttcc atcatttaat
    36781 ataactatac catgtaaagc aagtggaata gccgtccatt ggtatttttt tattccacca
    36841 taataatgag tcttaaaaaa acctagatta ctctcttgat acagtggatt tggttttaaa
    36901 tctaatcttg gcgaatctat atggcttcct ataatcttca tacctttttc tatataattt
    36961 ttacctatta caaaaagtgc tactgccttc tctttattta taacataaat tttatcacca
    37021 caacttatgc ttcctttttc catagcttca tctattgaaa tatagttatt ttctttagcc
    37081 aattttataa tttcttttac tgaaagtctt tcagtctttg acttacttaa aaactccata
    37141 taattgctag aatattgcat aatttgttca atagtatttt cttttctttc aaaatcccaa
    37201 gcattcttaa attcgtactt taagttcata ttttcctcct actaagttct aatttttatt
    37261 gtttttcatg tattgctcat attcttctgg tgaaactact ttgacactat ctagtcttga
    37321 tctaaagtgg gctctaaagt tttctaaata ttctttcctt aaaatttctc tttctttgat
    37381 ttcatcagca gaaaggattc cctctttatt tttctttgct aattcattaa tcctatctaa
    37441 tttcttcttg tcaaacattt tttcctccta aaaaacctct atttatttaa taaaataatt
    37501 tattgctttt tatatctaac ttgtttttat attcacaaaa aaactcatct atattatcac
    37561 ttattataga tattcccttt tctagttctt ccatgcttgg acgagctata tttatcctaa
    37621 agaatctatc atccactaga ttgtcaaaaa aataggtccc tggaagcatt gacactcctt
    37681 tgtttaacat aaaatttgta aatgcttgag atgtatatcc tcttggtaat tctaaaaaaa
    37741 agtttattcc tccacaagat tttctaactt ttaatttacc actcaatttg tcattaatca
    37801 agttttttgc caatttatac ttatcagtat atatcttctc tatatgactc aaataattct
    37861 tccaatcaaa attattcata tagtaataca ttgatttttg aattaaacct ggtgttgata
    37921 tatctgatga atatttagcc cataaaactt tttttaacaa ctcatttggc atttctacaa
    37981 ttcctatcct aagacctggc ataagtattt ttgaaaagct ttttatatat actactctat
    38041 ttttatcatc ataacttcta attgttctat tgtcctttga ttcaaaaaca aaatcactta
    38101 taaaatcatc ttctattata taaaaatcat gttcttctgc caattctatc aatttctttt
    38161 ttttatatgt tgagtaagat attccagttg gattttgaaa attaggcata atgtatataa
    38221 gtcttggttt tattttttcc aactttaatt ttaaaatacc tatatcaatt ccatcatcta
    38281 acataggtat agatattatt tttgcacctc tacttttaaa cacttcaatt gctccattgt
    38341 aagaaggttc ttccataaaa acaacatctg aataacttat aagtccttta caaactatat
    38401 ctataccttg ttgagcacct gatattattt gaatattttc cttagtagtt tttatatttc
    38461 catcacttag atactctacc attttttctc ttaattcttc agagccaaga ccttcatcat
    38521 attcaaatat tgaactacca tctttagata atgccatatt tacagcattt ttaaatgaat
    38581 cgataggaaa catatcatta gatggattcc cattgtcaaa atgaattaaa tcttctcttt
    38641 gcacaataat cttatttttc ctattatcta taccgctttt ataagaattt aaacttgata
    38701 caaaagtacc actccctata attttatata catatccttc attttctaaa agctcgtata
    38761 ccttaactat agtagtgtta tttacttgta aaaaatttga tagttttctt attggaggca
    38821 atttttcatg ttctactaac tctttattta ttatcaattc ttttatatga ttaaatatct
    38881 gtatatattt agttgatttt ttctcattta aatctattct gtatttttcc aaatttatca
    38941 ccgctcattg tatttatatt ttattgatgc ttttatgtat atttgatatt atttagtatg
    39001 tatatataat accaaaattt ttataaaaag gggaaatatt tatgttttac gactatcaca
    39061 tgcactcaag tttctctaca gacggaaaat ctacaatgga agaaatggta aaaaaatcta
    39121 ttgaactcgg tttggaggaa atttgtttca cagaccatgt tgactatgat gtatatgctg
    39181 atgattcttt ttcaattgtc tacgaagatt attttaagag tttagagact cttcaaagca
    39241 aatataaaga taaaatatca ataaaaaaag gaattgaatt tggagttcaa actcaattaa
    39301 tggatacata caaaaaggaa gcacatcaat atccattgga ctttataata tgttctatcc
    39361 atgctataga tacaatggac ttataccttg gtaattattt taaaaataaa actcaacatg
    39421 aagtttatga aaattactat ctttatttat ataatattgt taagaattat aaagattact
    39481 ctgtcttagg tcatttagat ttgattaaaa ggtatgcacc ttatgacact attttagatg
    39541 atagactatt ttctgatata attgaagaaa ctcttaaaca agctatttat gatggcaaag
    39601 gtatcgagat aaatacctct tgttatagat ataatcttcc agacctaacc ccatctaagt
    39661 atatacttca aatgtacaaa gacttgagag gggaaatcat aaccacaggt tcagattcac
    39721 atcatataag tcaagttgca tgtgagtttg actacatata ttcattacta aaaaatatgg
    39781 gatttaaata tgtatctaaa tttaataaat tgaaaccaga atttataaaa ttataaattt
    39841 ttacacctcc ttgtgaatat atttaaaaga taaggaggtg atttttttga aagtacctta
    39901 tttagtacta tcaacagtta ttttatttat atccaatttt attgtaagaa tatttggttt
    39961 tttatataaa atattcttat caagagcact aggtgaaaca ggtttaggta tctatcatat
    40021 gatttttaac tttttgatga tttgcttagc tgttacaaca acaggtatac ctactgcact
    40081 tagttgtcta gttgcaaaga gaaaagcttt aaacgataga cacaatacta atgctttatt
    40141 tatatcaact ttatatatat catttttcgt agcactaatt atatctatag ttgcatcttt
    40201 caatagttct tttttatcac ttaaattttt aaaagatgct aaattaaatc tatttatact
    40261 agctgtttgt cctgctatag ttataataac tctttcaaac gtactaagag gatattacta
    40321 tggcataaag aatgtaaaaa tccctgctat tggacaaatc attgaacaaa ttggtaaaat
    40381 attatttgtt tttttacttg ttatgtacat aaataataaa tctatgaatt gttatatagc
    40441 tctattaggt atatcgattg gtgagttgag taatattata tttatgctta tttgcttatg
    40501 gcgagattca tcatttgaca ataggtatat tataagcata aaagattttt ataattcttc
    40561 tatggaaaca ttaaaaatgt ctattcccat aacttgtaat agaatgtcaa acatactttt
    40621 gcaatctata agttctatga tgataccatc aagattagca ttatcaggaa tgacttatca
    40681 acaatcttta agtatgtatg gtattgtcag tgggatggta atgcctttta tatttttacc
    40741 ttttactgtt ggttcagcgc ttattgtaaa tttaatacca actatttcac aagaaatggc
    40801 tctaagaaag cgtaagagtg taattaaaaa aatcaaatac tccatacttc ttactttatt
    40861 tgtaggcata ctatcatcaa tattttttta tttctttgga aaagatttat gtatattagt
    40921 atttaaaaat acacttgcag gagaatatct aaaagctatg tttttagttc cactatttat
    40981 gtccctaaat caaactctat ctggcatttt acattcaata agaaaagaat tagcttcaag
    41041 tataaatact attactggca tgttaattca actaatagct ttatatgtat ttcttccaat
    41101 tccaggactt aatatttatg catacatata cacaatgacg atagtatcaa tctttacttg
    41161 tctattacat actatagtgc tttttaaatc actaaaatct atacgctagt tataaaaacg
    41221 tgaaggctac caatgtaaat tatacacttt ggtagccttc cttagatgat ttttatttat
    41281 aatttaaact gtctatatat ctacctatct atctgtggca acttggcttt ccacttccat
    41341 gattaggtcc acattgcgaa aaatcacata ctttagagaa agtatcaaca agtcttggtt
    41401 ggattggatt tggtgatgct aaaactacta tttgttcact tattaatgtg ctaactgttt
    41461 cttgtaagca aagtactaaa tctatatcat ttggtataat taattcatag aaaggttcac
    41521 aacattcgtt gcattctaat tttaatatag attttcctat acaatctaca gttaagttag
    41581 tttgatattc ttgtcttaaa gtaacagctc ttccgtcagc tggcaagcat attggtgctg
    41641 aaagtgtgtt aaaagtaaat tctacataat caactcttct cttacatcca cctcctgctc
    41701 taactgctgg gaaagctaat gcaacgaact ctgtacatcc acatctacct cttagctcta
    41761 gtactaaatt acgaactgct acagttaatc ctctttgttt ataagctact gatttgcctt
    41821 ttccttgtct acagcactca gagtttcttt ctccacaaac tgcaaattca aaagttgttt
    41881 cacagtttct tcctactata tctcctaatg ggtctaaatc gaaatcttct aaagttgtca
    41941 ttcctgtgtc tataacgatt ccatcattac ttaagcatat tttttctata gttacacttg
    42001 cttgacctgc acttggaact gaaccaaata cttctactac ttctgtttca aaagttaatg
    42061 gctctccatt tggtcctgtt gcatctgtaa atgtttggaa ttgcatagta tcaaatattc
    42121 tattagcctc tattgcaaat ggcactgcat ttgatacaga gaagtttctt ggagatatag
    42181 gattacagca ttctggtcca catttgtttt caaaacattc atctgaatcc atttcacatg
    42241 gttcacaatc acatttacaa ttgtcatggc atccacaatt gtcatcacat ggattaggtt
    42301 tgcatggatt gcatgggtta ggtttacatg gattacatgg gttgcatgga ttgcaatcat
    42361 catggcactc acacttatta tcagtattac atccattatg atggtgtgat tttttaaaac
    42421 ctctcatgtc ttctgaattt atttcatctg tatacacttc ttcttcattc attgtagaca
    42481 ttggctgatt catcattctt cttttatttt ttttataatc ttgcattttt cattgccctc
    42541 cctgtaagcg attcttatta agtctttggc tttttgaagc ctaattaata ctatgctttt
    42601 ataatcttaa ttgttacttg ctttttgaat ttatcaataa ttaggcgtat ttagtagaaa
    42661 aatgcatatt aataaaaaaa gtactactat ttgaaatagt agcacttttt ttgtcccgaa
    42721 acaccggtgg ctaagtaaat tcacacccta ggcactccca ggtgggtgac ttgccagtaa
    42781 cctttaacgt ccaaactaac taggcatgtt ataatttacc agacacggtc tcccgtattt
    42841 catttgtagg ttgaatttaa aaaagcctta tcgtatgttt caggatttca tattattatt
    42901 atataataaa ttttgaattt tttaaagtgg ttttatatag taattgagat aatcttattc
    42961 tatcattact ttttcttcct tttttcttta tgtatttagt taattatcgt tttttcttag
    43021 ctctagtttt agtatttttt tcattataat tgtattcgga ttcttgctca ttaatgttgt
    43081 atagttcctc atcgtatact atatcttcat cattttctat attttcatag cctgtgttct
    43141 tatcttctac taattcatct tcattatcct ccatttcacc ttcatctgtt aactcatcat
    43201 catccaattc tttgtcttca caatctaatt cttcgtcttc ataatttaac tcatcattat
    43261 tgtcttcatc atcattatta ctatcatcac ctcttaaaag acttcctaac aatttgagat
    43321 tattcatact accaagattg tttatatttg ccaaagagct caaactaaat ccaccttcac
    43381 caaagtcatc tggtaaaaat aattctgcaa ataaatctat cttctttttc attcctatag
    43441 ctttttcaac tgaatttttt cttttttctg ggaatacatc tataatttcc tttatcatca
    43501 tattcttttt atcatcacta tccatttttc tgaaaaaatc cgtttcatct tctgtatcta
    43561 ccatatctat attatttaat ttttttattc ctctaactaa atctaaaaca ctttctattt
    43621 ttattagtat ttttctttca tctcttgaca tgtatttttt agttcttgtt attatttcca
    43681 ttcccatttc taaatcttct tcacttaaat ccatgagcct taaacctctt tttatatcat
    43741 ttgcatcaaa ccttaaattg ccatgtgtag actgtgaaag tttatcattt gcattttttt
    43801 tgttttttct aactctatta tttccttttg atttattttt atcatcaaat atagagatat
    43861 taccattact caatgcaatc actccaatca aaaatagtaa gttattcaag acaattcccc
    43921 cttatattat ataattgccc tatattaaag tatgtttttc atattttaat gttccatttt
    43981 taaagctcag tgcatatata ttatctataa gaatttttat ttatattata tatcactcac
    44041 aattcaccac ttcaatatta tttctatata taaatagtat gaatataatt caatatatat
    44101 ttatagaaag gggttttttt atgaaaaaat tagatacaga gtcattagaa aaaatggcta
    44161 aacaaaaaaa tattgacaag gataaaatag aaaagatggc tgatagttac aaaggaaaat
    44221 cagaaaatga acttatggag gaacttataa aaataggtaa gaatctagat ggcagagatg
    44281 aagtagtatc aaaattcaaa gcatttttag atgaaaatca acgcaaaaaa ctggataata
    44341 taatggaaaa aatctcagat gcagaaaacc aaagagatac taaaccagct aaaactaaga
    44401 aggctaaacc tactaaaggt aagtcaaatt cacctgcacc aaaaaataca ccaggtagtc
    44461 aacaaaaaaa atctaaaagt ttatttaaga aaactaaaaa gtctaatcct catgaataga
    44521 taaaaataaa ctatttaagc aattagataa ttatttttag ttaatctatt attaaatttg
    44581 atattattga cataaaaaat caggtagtgc ctaaggcact acctgattga ttttaatagt
    44641 tttatttttt tctttctgta acactttctc tatcaacaat tctataaggt aactctattt
    44701 tcttattttc aattaattcc ttatttatta attttataac cattcttatt gctactgctc
    44761 ccatatcgta tagaggttga tatactgtag taagtttagg tctatacatt ctagctatct
    44821 taacatcatt aaatcctgca actgatatgt cttctggaac cttatatcca gcatcacata
    44881 tagcatttat agcacctatg gcagcctcat cacctgttac aaaagccgca tgaggtatta
    44941 ttccatcatc taatagttct ttcatactat tgtatccact ctcataatca gttccaccat
    45001 acttaatcaa actcttgtct aattctatat tgttatttga aagtgctttc tcataaccag
    45061 caagtctttc catttctaaa acagtatcat ctttactagt cattataaaa gctatctttt
    45121 catgaccttt ctttataaga tgctctgtca tatcaaaagt agcttcttcg ttgctagtac
    45181 ttactgtata tatatcataa tttctagcag ttttacttat atatgtcgct ggtattccac
    45241 aattttgtat atagttgata tgttcttgtt caactatcca tgaaatcata actatacctt
    45301 ccacttgttt tgctctcaat agatttatac tcttaagttc ttgttcctta tcagagtatg
    45361 tattcgctaa aagaatatca tagtcataca ttttagcaac ctcttctatc ccatttaaca
    45421 cctcattaac aaaagaatct gaaacttctg gaactattac ccctattaat tgactcttct
    45481 ttgttactaa gcttctagca agtggatttg gtatatatcc agtctctttt ataacctcta
    45541 aaactttttg tttgacttca tcagttacag gttttgaatc atttataact ctagatacag
    45601 tagatattga cactcctgct tgtttagcaa catcttttat cgttatattg cctttcatct
    45661 tcatcctcct tattttacta aatttatcta aaactgaacc aaatttttga aggttcctat
    45721 tttaactaca tttatataag tttttatttt accataaaag caagtacatt taaatacatt
    45781 atattttata ttatacccta tattcaacaa atttaataat attcattctt aatttaaatc
    45841 atattaaaaa ataaaataaa aaaatgctgg tataaaatac cagcattttt ttattctaat
    45901 gatttaagta ttagcagccg caacctactt caccatcaaa gaatccacca catgaacaag
    45961 ttattagcaa taatattaag aaaggtatcc atgacattat gtcaatgtct ctccagcaat
    46021 cttcaaaagc taagaatagg aagaatagta ctattatcca ccatcctcct ccaccaaagc
    46081 atccttcttc tccaaaaaat ctatctaaca taacaaagcc ctcctttttt taataactgt
    46141 gttcttattc taagcatcca ccacagcagc aaagtattaa taaaactatt aggaatggta
    46201 tccatgccat tatgtcaaat tctgcccagc tatctccaaa agctaagaat aggaagaata
    46261 gtactattat ccaccatcct cctccaccaa aacatccttc ttctccaaag aatctatcta
    46321 acattatacg ttacctcctg ttgatatttt gttgagcttt tcgctcctaa catatactat
    46381 gcatttggtt tccattttgc taatgtattt ttactatttt tttaaatttt ttaatttgaa
    46441 ctaaaaaagg taaaaccata acttgtataa gttactggtt ttacctattt aataatcaat
    46501 attttttagc aacaacaacc atcatcgaag ttaaataata acaatactat taatataacc
    46561 catatccata tattgtcatc gcataataag tcttctaaaa tgtctgtgca taatagtaag
    46621 aatactataa ctattattat caacatttta ttcccaaaaa atccttcgca tcctccaaag
    46681 aaacgttcca tattgtcttc taattttgtc ataactaatc ctccttgaat cattaagaga
    46741 ctaagttttg tctctttaat taaatatatg tagtaataga cagataagtt acttctaaaa
    46801 agtttttatt gattagttta tttatttctt tttcaccaag tttattgtat ctatcaactt
    46861 catccagata atcttttttc tcctctgata tagtatagat taaactttct attgatttta
    46921 ttttgtactc cttatatctt tctatcaaga aggatgtttt tgaattttct attcctttct
    46981 ttacatgcat taaccttgat atgtaatctt ctttttcatt agatacataa ctctcctttt
    47041 cagctacatc ttcaaggatt aaattggtct ccattacata atcctctata cgttgcatat
    47101 ctaaagttat tgaattataa taaaaattta ctgctataag taaaaacatt cctactgaag
    47161 ttagtaatag tcctacatat ttcatagcat ttcctcctaa gttatatttg ttatcaataa
    47221 agtttattca tcaaataata ctttattact acatttataa aattttatta ttttttatag
    47281 attccatatt gaaaaattct tgatattata ttaaactaac attaaaatta attaaaactg
    47341 ctttaggagg cttaaaatgt ttgagaaaat aaaagaaata atagcagaac aattaggggt
    47401 agacaattta gatgagataa ctatggaagc atctttaatg gacgacttag aagctgattc
    47461 attagatgct gttgaaatta taatggccct tgaagatgaa tttggaatag aaataccaga
    47521 cgaggaagct gaaaacttta aatgtattgg tgatatatgt aaatatatcg aagaaaacaa
    47581 atagtatcgt tttgtctaca aatataaata gtctgtgtaa acttctacat aataaattat
    47641 attagagttc gcacagacta gattacattt atttacaata tataaaatac acgctcttat
    47701 atttaattta tatactaagt atataaatta cttttcttca taaaacataa cattctttat
    47761 tattatatct atagttccat cttgattttg ttttacagta tacttcattg ggtcttcaaa
    47821 atcagttaga ttccctttta tgtcaaaacc attatccgtt tttatacttc tttttttaag
    47881 ctttttctca acccattttt tatctatact aaaactttcg tcaagacctt tttcttccat
    47941 atgctcttta aagctatcct ttaactcatc atctttaatt gaattatcaa caaagtcatt
    48001 tatatcaact tcatgttttt ccttcagtgt ataatttaat atacttctta catcttcagc
    48061 ttgctttata tcattactaa gagcattggt tatccaattt tcagctgtat ttttaaatac
    48121 cttggtcttg tacttatcat catctatttt tttagcattt aaaaattctg ttacaaactt
    48181 agattctgac ccttcttttt cagcatcctt atctaaaagc cttagatgaa actcatcatt
    48241 tataccactt agactaatca aagctccttg cttttgtctt aaagtctctg ggataccaat
    48301 ttcatttgaa accatttgaa tattaaattt atcatccaca aattcaattg aatgagtgta
    48361 caacttttta taatctaatt tcagtattgc tacactcttt tcatctttaa tagtgtataa
    48421 acaaattgcc aaatcacaag attctagtgc agcattaatt ttcataacgt caaacaagta
    48481 agatgcaatt tctttagaat ttttcaaaaa agtactttca tcatatatta tttgttcaca
    48541 acagttttta attaaattgt cattataatc tttaaaaaca ccttttctta aatcctcatc
    48601 ttttgcaatt ctttttatag ctttctggaa aaaaccatcc acttcttgat taactttgcc
    48661 ttcaaagtca tttaatattg gaacatcact atttttgtcc aaaacatgta ttataaattt
    48721 atgtattatc atatatatca ccccattatc ttaatttcga tattaactct ttcatatcct
    48781 ctggtatatc tgctttaaat ttcaattttt cttttgttct tggttgttca aactctagct
    48841 tatatgcatg aagtgcttgc ctatttatta gctcttcatc tacataacca tacaactcat
    48901 cacctattat tccatgacct atatgagcca tatgtactct tatttgatgt gttctaccag
    48961 tttctaagct tacttctaat acagttgcat tttctagtct ttctattact ttatagtgag
    49021 taacagatga ctgtcctctt tcatctatta tcctctttat tgaatcttct gtaggtctat
    49081 aaattggctc atctatagtt ccctcatttt cttttataat tccatcaact actgttatat
    49141 actttttttc aactttattt tcactcattg ctatagacaa agtatgatgt gcataagcat
    49201 tttttgctac tataactaac cctgaagtat tcatatctaa cctatttaca aatcttattt
    49261 ttacgttttc tttttgatta tctatatagt aactaatacc atttgctatt gttttatcat
    49321 agtggctttt tgttgggtga actaccataa acggaggttt attcaccata attatatcaa
    49381 aatcatcata aattatctgt aaatttaaat cttgaggttc aaaatttgct ttttcctcgt
    49441 ctatttttac ttctattaaa tcaccactat acacctttaa actcggtttt ttatatactc
    49501 catttactaa aacactcttt tccctcttca tttttgataa tgacctaact gagaaattta
    49561 gcttgtccaa taaaacttct tttaaagtca tttcttcttc atttgtatac gatataagat
    49621 tatatctttg attctctttt ttaaacaaac ttttacctac tttcttttat atcttcctac
    49681 tttttatatc ttcaaaatca tgatattata tattttacac tatttttgtt taatagataa
    49741 taattatttt taactataaa aacctgtaag aataacaaat agttattctt acaggttaaa
    49801 ttcataatta aatatttaat ttgtaaatat tataatctaa aactatctct taactattaa
    49861 agtagttccc attcctccac ctatacaaag tgtagcaaga ccagttttag catctcttct
    49921 cttcatttca tataaaagtg tagtaagtat tcttgctcct gagcatccta ttggatgtcc
    49981 tatagctatt gctccaccat taacattaac tttgttcata tctacattta agtctcttat
    50041 tacagctaca gattgggcag caaatgcctc attagcttca actaaatcta tatcttcaat
    50101 agtcatatta gcagcttcta aagctttttt agttgctgga actggtccat atcccattat
    50161 tttagggtca acaccagctg ttccataaga aactatagtt gcaagaggct ctattcctag
    50221 ttcttcagct ttttctttag ccattactac tagcatagca gcaccatcat ttattcctga
    50281 tgcattacca gcagtaactg ttccatcttt tttaaatgca ggtcttaact tagcaagttt
    50341 ctccattgta gtgccaggct taatatattc atctttatct actacagtgt caccttttct
    50401 tccttttata acaacaggaa ctatttcttc atcaaatttt ccttcagctt gagctttttc
    50461 agctttattt tgacttgcaa gagctaattc atcttgttct tctctagtta tattccattg
    50521 ctctgctatg ttttcagcag taatacccat gtgatagtta ttaaatatgt ctgataatcc
    50581 atcttttatc attgaatcaa caaaagcagc atcacccatt cttgcaccat atctcgcact
    50641 tggtactaaa taaggagaca tactcatgtt ttcagctcca ccaactaaca ttatatcagc
    50701 atcacctaat gctataagtt gagatgccat tgaaacagat cttaatccag aaccacaaac
    50761 tatatttata gtcatagctg gtttttctac tggtattcct gctcctaatg ctatttgtct
    50821 tgctatattt tgtccaagac ctgctgtaag tactccccct aaaagagatt catctatcat
    50881 atctggagtt atgttagctc tttttatagc ttctttagct gctgttaccc ctaactctac
    50941 cgctgaaact gatttaaatg ctcctccaaa acttcctact gctgttctag ctgcactggc
    51001 aattactact tctctcatat tcattacccc cattaaatta gatttttcat atatccgaaa
    51061 ttgtttttta aacaatttta tttaaacttt taattcccaa attcttattt attataatca
    51121 tagaatccta tcttagtttt tcttcctaat tgattagctc taaccatttt agctaaaagt
    51181 ggatgaggtc tatatttagt atctccaaac tcagtatata aaacgttcat tatagctaaa
    51241 acaacatcta atccaattaa atcacctaat gctagtggtc ccattggatg gtttgctcct
    51301 aatttcatag cttcatctat ttcttcttta cttgcaacac catctgcata tataccaaca
    51361 gcttcattta tcataggtat aagtattcta tttactacaa atccaggaga ttcagataca
    51421 tctactggta ctttattgat actcttagat aattcaaata ctgtatcaaa agtaactttt
    51481 gatgttaact gaccacttat aacttcaact aatttcatca taggaactgg attaaagaaa
    51541 tgcattccta taactttatc tggtctctta gtagaagaag ctatttctgt tatagataat
    51601 gatgaagtat ttgttgccaa gatagtatct tctttacata attcatctag taacttgaaa
    51661 acatctttct ttatattcat gtcttctaca gatgcttcta ttattaaatc catatctttt
    51721 aaatcttcat agttagtagt tgaactaaca tgacttaata tttctgcttt tgtagcttca
    51781 tccatttttc ccttagtaac taacttagtt aaatttttat ctaataaagc taaacattta
    51841 tctatagcac cttgagttct actctttaaa catacatcat gtccacaact tgcaaaagtt
    51901 tgtacaatac cacttcccat agttccacta cctattacag ctaatttcat agttataacc
    51961 tcctgttatt ttagtattta tattctgtta actagattaa aatactattt aatctagtta
    52021 acagcaaata tatttttaat tagattttta cccttttata aagttagctt ctctcttttc
    52081 aacgaaagct gacattcctt ctttttggtc tttagttgaa aaacaaagac caaataaatt
    52141 agattctata tctattccag tatttatatc agtttgagca ccaagttgta ttgcttcttt
    52201 agagtatcta actgcaagct gagcattttt agctattatc ttagctaatt tctcaacttc
    52261 ttctattaaa atgtctggct caacgactct atttactagc cctatttttt cagcttcatc
    52321 agcttttata acttgacctg taaagattaa ttcttttgct tttgccattc caaccaatct
    52381 tgtaagcctt tgagttcctc catatcctgg agttattcca agagttactt ctggctgacc
    52441 aaatttagct ttagcagatg caattcttat atcacatgcc attgcaagtt cacatcctcc
    52501 acctaaagca aatccgttta cagcagctat cactactttt ttactatttt ctatttctcc
    52561 aaaagctttt gctcctaaga tactaaaatc tttagcagct acagcatcta aatctttcat
    52621 gtatgcaata tctgctccag ctacaaatgc ctttccttcc cctgtcaata ttacaacatc
    52681 aatagtttca tcattattaa tatctacaaa tacttcataa agttcttcta aagtctttga
    52741 atttattgca ttaagggctt taggtctatt cattttcact gtacatatat ttccatctac
    52801 ttcaacagct acattctcat aaactttaac atcacttgta ctcataatac cctccccaag
    52861 aaattagtta gctaaaactt cacctttttc ttttgcaaca cttaactgac tgataagttc
    52921 tggaagcact ttatgaacat ctccaactat accaacatca gcatatttaa atattggagc
    52981 ttctggattt ttatttatag caactataaa ctcagcatct tccataccag ctatatgttg
    53041 tattgctcca gatataccac atgctatata aaggtctggt cttacagttt taccagtttg
    53101 accaacttgt cttgctttat ctaaccaacc tgcatctata gtggcacgag aaccagaaac
    53161 ttctccacct ataatttcag ctaattcata aagtatgtct aagttttctt ttccacccat
    53221 tccacgtcca gcagaaacta atatcttagc atcttctatt ttaacttgtt ttttagcttc
    53281 ttttattact tgtacaactt gaactaattt atcagcatca ttaaattcta ccttgaaacg
    53341 gttaattaca gcttctttag tttcatcagg ttcatttttc ttcataaccc ctggtctaac
    53401 tgtagacatt tgaggtctga aatctttaca aactattgtt gccattatat ttccaccaaa
    53461 tgcaggtctt gtcattaata ataattttgt atcttcagct actgcaagac ctgtacagtc
    53521 agcagtaaga cctgtatgta ttctagcaga aactctagga gctaaatctc tacctattga
    53581 agttgcacca aataatacaa ctatagggtc agctgctttt attgcttcat aagctgcttt
    53641 tgtatatggt tcagttgtat acactgctaa agcttcatca tctactacta ttacctcatc
    53701 tgcaccatag tgtgctaatg tatctattaa accttctacc ttactaccta aaagtaatgc
    53761 agaaactttt gtatcataat cttttgctat ttctgtagcc tttcctagta attctaaaga
    53821 aacagtttga attacatttt ctctttgttc tattactact aaaacgttac ccattcttta
    53881 tcccccctta aattatatga tatacttctc ttttaattta tctatgataa ttccagctga
    53941 tgttttcgca tcttcattgt atattgtacc agctggttta actgattttg taaatgattt
    54001 aaatacacta gttggagaac ctttaagacc taaattagaa gggtcaactt ctatatcttt
    54061 tacagtccat gtttctacta catcattttc gaaagcatca tatattcttc caactttcat
    54121 gtatcttggt gtgttcatat ctttaagagt tgttataagg catggcattt taacttttaa
    54181 gtcatggcaa caatcttcaa attgtctttt tactaataca tattcacctt cagtttttat
    54241 ttcttcagca tatgttattg atggaagatt taaatgttca gctatttgag gtccaacttg
    54301 tgcagtatct ccatctatcg cctgtcttcc agctattata atatcaaaat ctatattttt
    54361 taatgctcct gctaatgctg atgaagttgc ccaagtatca gcacctgcaa atgctctatc
    54421 tgttaataat atacctctat ctgcacccat tgctaaagct tcttttaaag ccatatctgc
    54481 ttgaggaggt cccattgtta taacagttac atgagcaccc atttcttctt ttaattttat
    54541 agcttcttct aaacctgctt tatcatcagg gtttattata cttggtactc catctctaat
    54601 taaagtacct gtattaggat ctagtttaac ttctgttgta tctggaactt gttttataca
    54661 aacgactata ttcataaatc cttcctccat atctatttta atatcgacct attgtgtata
    54721 ttttaatatt tatctatttt aataattttc ctgaaataac cattctttga acttcactag
    54781 ttccttcata tatttcagtt atcttagcat ctctcatcat tctttctact ggatagtcac
    54841 gagtgtatcc atatcctcca tgaagttgta cagcttttgt agtaacttcc atagctgttt
    54901 cagctgcaaa taattttgcc attgctgctt ctactccata aggttttcct aagtctttat
    54961 ttatagctgc ttgatataca aggtgtctag ccgcttgtac cttaacttcc atatcagcta
    55021 attggaattg tgtattttgg aattttgata atggtctacc aaattgtact ctttctttta
    55081 catatttaac agtttcatca agagcacctt gtgctaaacc taaagcttgt gcagctatac
    55141 caattctacc accatcaaga gtagacattg ctatcttaaa tccttgacct tcttttccaa
    55201 gtaaattttc tttaggtatt ctgcaatcct caaatattaa ttcactcgta gctgaacctc
    55261 ttatacccat tttcttttct ttaactccaa agctaaaccc aggagttcct ttttcaacta
    55321 taaatgctga tattcctttg ttccccttag atttatcagt cattgccatt actacatata
    55381 tgtcaccagc tattgcgttt gttataaata tttttgagcc attaagtatg tattcatccc
    55441 cgtctaaaac agcagttgtt tgttggccag acgcatctgt accagcatta ggctcagtaa
    55501 gaccaaatgc tcctaatttt tctccacttg ctagtggtct taagaatttt tgtttttgtt
    55561 cttcattacc atattgatat ataggccatg agccaagaga tgtatgagct gataatataa
    55621 ctcctgtagt accacaaact ctagacaatt cttcaactgc cattatatat cctacagtgt
    55681 ctccaccttc tccaccatat tcttttggat atggtatacc catcattcct gcttttgcca
    55741 ttttttccac tgtttcataa ggaaatcttt cttcttcatc aagttctgtt gctaaaggtt
    55801 taacttcatt ttcagcgaag cttacatata gctctttaag catctgatat tttttagaat
    55861 ttaaatccat aatagcctcc tcagtatttt ataaatattt tattttcatt tattaattaa
    55921 aatctcggca acatctataa taaggtattt gaatatacgt cgagaaattt ataaccttaa
    55981 tcaaactacg ctctatattt atatgtgatt atactaacca attatgacat taatttaatc
    56041 ataaattgtt aatttaaaat caactatact taaaaaaaat ctcgcttttt ggaattttgt
    56101 gaaatttcaa gttagaataa gatttctttc acactggtta cagataaaat aatttgttta
    56161 cgatatttat attagggtat attaaacatt aaatattgtc tgtacatctg ttttttagcc
    56221 atgtacagaa gatttttatc gtataaaaat tattttaata gagctaaata atcgtatttt
    56281 tatctgacta ttttttattt ttaaatatct tacatctata atagtatcac tcaaaggata
    56341 atttttcaat aatttctaat tattttttta acaatattta ttacattttt tccacttttt
    56401 tgtcattttt ttattgtttc gaaaaaaaat cagaattttt taactttatt ttggattatt
    56461 agtttaaatt agattttcct cttagattta taaatattta cacaaaaaaa ctacctctgt
    56521 atagattgta tacagaggta gttttttact aattcctact atagtttact atattttttt
    56581 accaattctt acaaacatct acccattttt cacacttaga aaacttctcc atttcttcac
    56641 atgtaagttc tattgcagag ttactactgc cacatgcagg aaatactgta tcaaatcttt
    56701 tcattgaatc atctaaatag acttttatag aattttttaa accaaatgga cagactccac
    56761 caatagcatg tccagtaaac tccaagactt cttctggtgt caacatttta gccttacaat
    56821 taaattcagc cttatacttc ttattatcaa tcttagcatc accagctgtc acaattaaaa
    56881 ttgcatcatc tcctttttta aatgagagtg tcttagctat tcttgctgga ataaccccag
    56941 ctgcttcagc tgcaagttcc acagtagcac tagattgttc aaattctaat atactgtctt
    57001 ccttgccaaa ttgtttaaaa tactctctta cattacttat tgacattaaa tatccctcct
    57061 agtctgaact tttataaatt tcatattatt cttaattata tctataattg atttattttt
    57121 caaattattc catgatatta gcattccatg tatcattatt ttttccaact actagataaa
    57181 gtccttttgc cattggaata ttgacaatat attctccttt atactctaca ctcataccag
    57241 attcattaaa gtacctataa tcaaaattta gtccttttgg aattacaaaa tcaacataac
    57301 cttgattatt tggttttatt ccatatttca gagttctttc agttatagaa tttttttcat
    57361 taaataaatc tacatttaca tatgcagaac acttattcat tcccttttta ttttccacac
    57421 aattttcaaa cttcatttta gcactgttta atttataact atatttacta ttattgctta
    57481 ttttaaatct tacaatagta ccaacatctc tacttctcct gctatcaaaa tcaaaaacaa
    57541 tttcctctaa atgatttatt tcataatctt tgacacttac catatctcta tatactaatt
    57601 tatttatagc tatgaatagt gtaaaaatcc ccaaaataaa aaatgaaact tttataaact
    57661 tcttcatttt tagtctcctt atattttgtg ctattgtgct ataatattaa tcaaaatttt
    57721 aataattaaa cttattcttt tttgaaatct taatagaaaa atacattgat attataaaaa
    57781 ttattattgt taaaaatgtc atactatata aatttatata cttagtatta gctatatcag
    57841 ttacataatt tgaaagatat actcctccaa ctttactata attaaaatgc tttacttgat
    57901 atacaatcat actaatcatc ttcaaaagac ttccatatac aaagtaaatt aaaatactta
    57961 ctataaaacc acaaactttc atttttccat atccaaactt aaaaattaaa ggcagtaaaa
    58021 tcgtcaaaat tgctaaaaat atatttacag aaaaaaatac atcatttaaa accatatttc
    58081 taaagaacac tagtgatgtc aatttactta gtaaggacac aattattgtt acagaaatta
    58141 ttaatcctac acctaataaa tattttgagt aaactatatc ttctatacta actggcatac
    58201 tccttataaa aatccttgaa tcattttcat aatcacactc aaatgtattt ataaatatca
    58261 aataactaac aacaatactt actgtataat atgaaattga attaaggaaa aaataaaaca
    58321 caaaaaatag caatatgtac tttaaattac ggataccatc tgaactaatc cctattatta
    58381 aatcttttct tattaaattg aacatcatct cacctcattt acataataat acattagttc
    58441 ttctatagta ggatttttga ccttatgctt atcaatttct atcaataggc tttttacttt
    58501 caagctatct ccaactttaa caagtgcctc attataatat ttatactctt tcacaccaac
    58561 tatgctttct ttaattgctt ctaactctgc tttatttgcc ctaattatct tatattcttg
    58621 ttctattaat tctttcttaa cagtaaaaat ctgatttcct ctatttataa aaacaagata
    58681 atcagcaatt ttaattaaat tatcagtatt atgagtagaa attattacac tactacttcc
    58741 atttttcaca aaatcttgta agtactgcat tatttcagtt cttacaattg ggtctatacc
    58801 agcagttggt tcatccaaaa tcaataactt agcattatga ctaagtgcgc ttgataacat
    58861 aagcttctca gattgacctt tagataaatt ttcaatatgc atattttctt ctatatcaaa
    58921 cttattaagg tattcatcaa acctttctct atcaaaattc ttataaaata aagaaactat
    58981 ttttctaaat tccttaacct ttaaatgcgg ataaaattgt aaagaatcat atacaaaacc
    59041 aatattgttt ttaaagctta ttggagaatt ttcaatagtt tcattacaaa gttcaatttc
    59101 accttcatct gcatcaataa tccccattat aatttttatt aaagtcgttt ttcccgaacc
    59161 atttggtcct ataatcccaa caatatcccc ttcctttaac tctaagttta tattatttaa
    59221 cttgaatttt cctaattttt ttgtgatatt ccttatgcta aacacatctt cacctcttat
    59281 gcattttttt atacccacct atacatattt taacacattc actacaaagg tcatttataa
    59341 atttataaat taagaattat aaaactatgt tataatacaa agtatgaaga ggtgaatata
    59401 tgaaaagaat tataactata aatacaaacc aattaaataa gtcccttgag actaaagaac
    59461 tcttaactag aaaacttatc aatgctggct ttgaagtgta ttcagatatt tatccagata
    59521 cagatcttat tatatcaatt ggtggtgatg gctctttttt aagaacagtt agagatttcg
    59581 attttcctga aattcccata atgggaataa atacaggtca tctggggttt tttcctgata
    59641 ttttaccaga taagattgat agctttattg aagcttatac aaaaaaagat tatattattc
    59701 aagaaatgtc acttcttaat gcggaagtat atacaactac tagtggttct aatatgcttg
    59761 ctgtaaatga ggttgttata agaggagaca agtctaggac tatacaccta aatttaagcc
    59821 ttgataataa acatatacaa aattttagtg gagatggtat gattatttct acttccacag
    59881 gttcaacagc ctataactat tctgctggag gtagtattgt tgatataaat cttgaactta
    59941 tgcagattac acctttacat ccgataaata ccaatgcata taggtgcttt acatcaagta
    60001 taatatgttc aaatgaatct gttataaaga ttgcaccaga atatagattt gaagattctg
    60061 tattgattgt cgttgatgga gttgagcaca gatttagaca aattgaaaat ataaaagtta
    60121 gtatatctga tgcaaaaata aaattactta gaatgtcaaa ctatgagttt tggcatagag
    60181 tatctgaaaa atttttatag actgtactta ggaggatttt taatatgaaa ataggaataa
    60241 tgagtgatac tcatggtagc ttactttact ttgaaaaagc gttaaatgta ttatctgatt
    60301 gtgatgtttt attacatggt ggagatgtct tatatcatgg acctagaaat gatattccag
    60361 aaggatataa tcctaaaaaa tttattgaga cattaaataa attagaaaac attgtgattg
    60421 taaaagggaa ctgtgatgca gatgttgacc agatggttat agaacatcct attcagagtc
    60481 cttatgtcat gagccaattt ggtgaaatta gaattatatt gaatcacggt tatatagaat
    60541 cagaagaaga aattattgac aaagcaaaga aaatgggtgg tgacgtatta gttttaggac
    60601 atactcatgt aaaaaaacta tacatggatg ataatttaat agtaataaat ccaggaagta
    60661 cttctatccc aaaagatgga agccattctg tcgcaattat agatatcata aaaactgatg
    60721 atgaagatga gcttgaactt gatataaact taattgacat caatactgga aatataataa
    60781 atatcaatga ttagtaaatt tttaataaaa ataaaataag ctttaattta ttaaactcat
    60841 aataaaaaca agtaaaccat tttatttcta tctcaattag aagtttaagt acaatacctt
    60901 aaacttctaa ttaaatagaa tctggtttac ttgttttatt atatgctata ttgaaatata
    60961 acttagttta cttgtttcta ttatatatta tattggagta taacttagtt tacttatttc
    61021 attatatatt atactgaaat ataacttagt ttacttattt cattatatat tatactgaaa
    61081 tataactt
//
LOCUS       DAEPUT010000011        59771 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.011, whole genome shotgun sequence.
ACCESSION   DAEPUT010000011 DAEPUT010000000
VERSION     DAEPUT010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 59771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59771
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.011"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            19..180
                     /locus_tag="KRL22_000828"
     CDS             19..180
                     /locus_tag="KRL22_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271343.1"
                     /translation="MAIVVIGIYLGLKREFSKLIGFLVVALIAVGLVFNASGVKDVLL
                     ELFNKIIGA"
     gene            240..1013
                     /locus_tag="KRL22_000829"
     CDS             240..1013
                     /locus_tag="KRL22_000829"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271344.1"
                     /translation="MKGIKVIMISDEMRVDILHAVFINQNFIKDEENCNYEKYLLELV
                     NKSIYFREKSNFAEYVPPKSENHGECDCNSPNYQMDFKLLEITTRLHASKELTGQIQK
                     FCDGVIGKCPPRRPNTQMTVTRLFASLRDYDCESLHSCLTEKYEYGTIEFDIQTYVKL
                     LTFKKNLFFFFPYKFSFNTCYNFKYALDSIRIALEKDFRESNLFREKYYAEYDTFLAY
                     IYEDNLIISKFEQDGKLQMIDCIYLFKSQTYSKLYEYTW"
     gene            1112..1408
                     /locus_tag="KRL22_000830"
     CDS             1112..1408
                     /locus_tag="KRL22_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1271345.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWHEMKRLNPADYEEKQL
                     EDFSKYVFGMSYQTLKDVMKQQKGREEQCRKQGYWWKREEQMAKKQHHTGLTYR"
     gene            1327..1830
                     /locus_tag="KRL22_000831"
     CDS             1327..1830
                     /locus_tag="KRL22_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1271346.1"
                     /translation="MQETRVLVETGRTNGEETTSYWFDLPIDVAEFEEKLGVGAESQD
                     YRIIEKVLPYADEVHEHTSVYQLNELDFMYRQLSADMQEEYVELLTVFENLEALYICR
                     NVITVYHDCKSMIDVARQKLMNDPTFKHLSEDCQAYYFDFEAYASHLLENKRYLVTEN
                     SIFELPE"
     gene            1848..2351
                     /locus_tag="KRL22_000832"
     CDS             1848..2351
                     /locus_tag="KRL22_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1271347.1"
                     /translation="MIDDMAVYIANLGRYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIDIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYFYPDCETMTDVAYYYIDELNALGDIPANLQNYIDYEAYGRDLDMGGRFIETSR
                     GICEIPY"
     gene            2469..2867
                     /locus_tag="KRL22_000833"
     CDS             2469..2867
                     /locus_tag="KRL22_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1271348.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            2845..5295
                     /locus_tag="KRL22_000834"
     CDS             2845..5295
                     /locus_tag="KRL22_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1271349.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLREVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIHDFGYLMEHLYGRDGIAYEDYEYQLPKKKLKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNVIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSENRGLLHVIEELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            5295..7499
                     /locus_tag="KRL22_000835"
     CDS             5295..7499
                     /locus_tag="KRL22_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1271350.1"
                     /translation="MKERIQSAFTKRKILHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFFVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTENGFSSTGFYVGFLLLIIL
                     VVGMYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVQQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRAERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQHKKSIAVKRMELQKAQEARQAQRKADGSATTGATRPHER
                     PATASTVSKTGAEKMQEVKRPATTPTTKASEPVKTSGVKERPLSSSTPDGKATQSTYR
                     QNVEKVTVSKETRQNYTKDRRTKVQQTQTVQKNQQTTEKIRNLVTKKGQKKK"
     gene            7496..8503
                     /locus_tag="KRL22_000836"
     CDS             7496..8503
                     /locus_tag="KRL22_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH1271351.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPSS
                     LDTESSIKQGCKYFASLLSSCKNQGIDDLNVAIQSYNYGGGYVGYVAGNGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVFGGSSPTTSFDCSGLTQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYTDLSSSYWQQHLIGAGRVK
                     Q"
     gene            8520..9422
                     /locus_tag="KRL22_000837"
     CDS             8520..9422
                     /locus_tag="KRL22_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1271352.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDQHTTHEKEVIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIDARTQAISG
                     YLTKELQDLNMDTIRTDIPTSSAITDVIVWSIEQSGTDTFSATYEVDQQIKEGEQTTA
                     VKATYTVKVHVDAGGNMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTINDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLESIGRDYLYSELVNPIFTVDGDNVKVKVAVKFIDN
                     QTKATQVSQFELVLHKDSNWKIIG"
     gene            complement(9621..9956)
                     /locus_tag="KRL22_000838"
     CDS             complement(9621..9956)
                     /locus_tag="KRL22_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271353.1"
                     /translation="MTHMSADKLLLGFHLDHVSNLNELLRKVAHNNICIMSDRMTKVA
                     VWKTSVKTIQLVCIEYLNYIIDHSVIYEKIQCANWNGTEETNSIFNNSPSPLITLIYS
                     CDLQQNKTT"
     gene            9906..10115
                     /locus_tag="KRL22_000839"
     CDS             9906..10115
                     /locus_tag="KRL22_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271354.1"
                     /translation="MVKVKTKKKFVSTHMCQGEMPIYVRESYEKMLAVSIRAPNLEGM
                     VENFDKDLSHPNETDLIELKNAISK"
     gene            10208..12871
                     /gene="mgtA"
                     /locus_tag="KRL22_000840"
     CDS             10208..12871
                     /gene="mgtA"
                     /locus_tag="KRL22_000840"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBH1271355.1"
                     /translation="MSKATLFDSRIKKYAYCRTSEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFVASNFARNATTAIII
                     FSMIVISGGIRLIQELRAKSAAAQLDRLVHESVTVRRDGKLIEIPGEELVVGDIVLFS
                     AGDRVPADIRLTKITDLFISQAAITGESAIIEKSCRKLSYGEQDTLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKNSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITDGKWMESFAFALSVAVGLMPEMLPMVITACLAKGSLAMSKKQTIIKDINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDIFGNENAEVLDLAYLNSCYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNHVEYRGKLLPMGQDARQSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGIYTERILTG
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEEGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEILSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLQLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIAFTSLTFVGGASLFGLTKLPLW
                     YFVFLLLVVSLYMLLSSVAKYFYKKKYQELI"
     gene            12887..13390
                     /locus_tag="KRL22_000841"
     CDS             12887..13390
                     /locus_tag="KRL22_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1271356.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDCAKDLLSGIQEMIR
                     GEVSSLLLGASEESDWPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWGEDYILDNSNIMAFIRKLRKKIEPAPDCPTYILTIWGIG
                     YKFNDQI"
     gene            13528..14205
                     /locus_tag="KRL22_000842"
     CDS             13528..14205
                     /locus_tag="KRL22_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH1271357.1"
                     /translation="MFYTDFILRIALSLTLGFLIGLERQLTGHPAGIRINVLICMGTS
                     FFTLFPMLYGSDQVFRVGSSIISGVGFLCSGVIFKDRGTVRGMNTAATLWCTAAIGIL
                     ASTGMYAMAITAATILIGSNLILRPFARKFHPITSSDESEKQYRISVTCQEKAEQDIR
                     LLLINSNSCKTLFLNNLESGDVVGDKVEIVAEYCSVGKSKNNILEGIVGQVLVIPEVI
                     SAGWEVL"
     gene            14452..14763
                     /locus_tag="KRL22_000843"
     CDS             14452..14763
                     /locus_tag="KRL22_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBH1271358.1"
                     /translation="MDFTCIFFGILFTLAGFWLAFGKGYRHLSLWKNMPQEEKDKINI
                     VPLCRNVGEMIALNGIIFLMKGFLPGFSNHWFVFAIIAWLIVAGFDVWYIEKSVRYRN
                     Q"
     gene            14929..17694
                     /gene="mgtA"
                     /locus_tag="KRL22_000844"
     CDS             14929..17694
                     /gene="mgtA"
                     /locus_tag="KRL22_000844"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBH1271359.1"
                     /translation="MNKKENRMAIRQTVEKAVIRDEQNHRIQFAATNPIKDVLKKLHT
                     TLRGLDVDEVSVSRAKYGTNKVTHEKKKSLAKRLVGAFINPFTAILFCLALVSTITDM
                     IFPYFSLFGSVPEDFDSLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNYEKKELPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTNIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLAAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEAADSRLIDLSENYVKVDEIPFDFTRRR
                     LTTVVQDNKGKTQMVTKGAVEEMLSICAFAECNGGVQPLTDDVRYRILETVDNLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECDMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVAESTDVFAKLTPDQKVRV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIFLNLIYDLSC
                     TAIPWDNVDEEFITKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFVQSRAS
                     APVTLLTMTGIIVLTIIPFTVFGTMLGFVALPAAYFAYLIPCILLYMTLATSLKKAYV
                     RHFGELL"
     gene            17707..17874
                     /locus_tag="KRL22_000845"
     CDS             17707..17874
                     /locus_tag="KRL22_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271360.1"
                     /translation="MNWKELWMTLFGTTEWLGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKKDTKESYK"
     gene            18924..19223
                     /locus_tag="KRL22_000846"
     CDS             18924..19223
                     /locus_tag="KRL22_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1271361.1"
                     /translation="MKHLHIQQLSTIGSSLKKHLNSTEYNAPICGFLQHITGIICLAQ
                     DQYVCIALVLFYCIKLFQKIFAVGYQIPPFTVSVSAKRGRSLFALATFAGKGVRL"
     gene            19220..19636
                     /locus_tag="KRL22_000847"
     CDS             19220..19636
                     /locus_tag="KRL22_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1271362.1"
                     /translation="MKPSSFEGAIRLQFDCLARKVVGRTVKNYDRELGRRARRETPFC
                     DLSEMELNQIGVMDEYCVEFTSFDVFGSEVHIYDERLCEAIKELTESRRNILLMSYFL
                     EMTDAEIAEVMEMERFSVCRNRLHTLKLIKDMYEEE"
     gene            19641..19880
                     /locus_tag="KRL22_000848"
     CDS             19641..19880
                     /locus_tag="KRL22_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1271363.1"
                     /translation="MMKSTKKCLSFSTISSAADGNEVAIEKILNHYDAYISKASLRPF
                     YDEHGNMYIVVDMELKGRIRAALMKAILGFEVKVK"
     gene            20198..20341
                     /locus_tag="KRL22_000849"
     CDS             20198..20341
                     /locus_tag="KRL22_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1271364.1"
                     /translation="MNNLIRYSMQIAMLKQLLARKLISEKEYTLVKQRLMKDYKVLSD
                     ITA"
     gene            20404..22164
                     /locus_tag="KRL22_000850"
     CDS             20404..22164
                     /locus_tag="KRL22_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1271365.1"
                     /translation="MQEVEVIKARNVLSKQARGKAIERLRVAAYCRVSTDSEDQLNSY
                     KSQVQYYTDMIKKNKEWVLADIYADEAITGTQVTKREDFQRMINDCMNGEIDMVITKS
                     ISRFARNTLDTLKYVRMLKERNIAVYFEDEKINTLTMDGELLLVVLSSVAQQEVENIS
                     ANVKKGLKMKMKRGELVGFQGCLGYDYHPEDKTITVNQEEAEIVRYIFNRYVEGAGGS
                     VIGQELENLGYKTKYGSSTWAPSTVIGIIKNEKYKGDILLGKTFTVDPISKRRLENMG
                     EEDKFYMKDHHEPIISEEIFEKAQEILNRRNKNRTTVGSGKREKYSRKYAFSCMLECG
                     FCGSTLSRRNWHSSSEYSKVIWQCVTATKKGKKFCPDSKGIPETAIEEAFIESYRLLC
                     DNNKDVLEEFLHRLDETLSNSTVSKQLSKIEKEISAVEGKKNKLVDMRLEDSIDKDTY
                     ETKYTALMEKLEQLASDRQKLQETAVNEKDIKRRLKEFKTTLEQNEVLDVFDRHVFES
                     IVEKVIVGGYDEDGNKDPAQLTFVYKTGMKNSVDGSRFKPQRKNARGRHRTDELCSHE
                     SNEVNSLCSDNSADTCGNCS"
     gene            complement(22658..23155)
                     /locus_tag="KRL22_000851"
     CDS             complement(22658..23155)
                     /locus_tag="KRL22_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271366.1"
                     /translation="MKKRKIVIITLLLIGVLLLGGILYNLFLVKTANISMLKESWNFD
                     IPIPNKEIEVFDTQDSINGDGQSYFIQEFSEKNFKKVFNLKGGIVVSKDNINEIEKYI
                     DKFKRDSVNINKSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYS
                     LIWNQ"
     gene            complement(23482..23652)
                     /locus_tag="KRL22_000852"
     CDS             complement(23482..23652)
                     /locus_tag="KRL22_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271367.1"
                     /translation="MFRDKMDRCTLTAYIGSSYDYCDFIDTQLDDFILEYGENVVESC
                     LHQVMVLVSKYN"
     regulatory      complement(23706..23802)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            24598..24999
                     /locus_tag="KRL22_000853"
                     /pseudo
     CDS             24598..24999
                     /locus_tag="KRL22_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
     gene            24996..26063
                     /gene="rsgA"
                     /locus_tag="KRL22_000854"
     CDS             24996..26063
                     /gene="rsgA"
                     /locus_tag="KRL22_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH1271368.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQVSKYIKPGCTVALLGSSGVGKSSLINC
                     LLGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKIE
                     YLAKKEKKFKNISKINKKIRR"
     gene            26601..27299
                     /locus_tag="KRL22_000855"
     CDS             26601..27299
                     /locus_tag="KRL22_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271369.1"
                     /translation="MKISSQYRSQYSFRHESNINNTRINESIVKKNETAGKDTYLSNI
                     MKQKQELNDRIRDLKDRQEIYTKKINEAIKNLYKSEIRETTNNFSNIEIGIKNRIIED
                     KNKSTMLDENSTYLNTNDEKESLIAKEFNEKVEEEILNDEKLEELEQKKDYKEDSNKK
                     ETVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKDAEEYKQNSKTNIF
                     DKTDEQKRRINTLV"
     gene            27477..28367
                     /locus_tag="KRL22_000856"
     CDS             27477..28367
                     /locus_tag="KRL22_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271370.1"
                     /translation="MKKNILTTVITMIIIFMMSMTVMAEQYQADETSSLKKQSENESN
                     QTSVGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALAGGSYQRIGFGKLDPIEVIADGDWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADAKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKYA
                     TREMTTYYDVKALSILGFNQ"
     gene            complement(28764..29720)
                     /locus_tag="KRL22_000857"
     CDS             complement(28764..29720)
                     /locus_tag="KRL22_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1271371.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISILDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRITDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSKILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            30422..31417
                     /locus_tag="KRL22_000858"
     CDS             30422..31417
                     /locus_tag="KRL22_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1271372.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLLNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSHKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKTSVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            31395..32258
                     /locus_tag="KRL22_000859"
     CDS             31395..32258
                     /locus_tag="KRL22_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH1271373.1"
                     /translation="MSIMSNYNEASSNSSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPL
                     VLLPETIVTVMKIFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            32255..33049
                     /locus_tag="KRL22_000860"
     CDS             32255..33049
                     /locus_tag="KRL22_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH1271374.1"
                     /translation="MIKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            33334..34713
                     /locus_tag="KRL22_000861"
     CDS             33334..34713
                     /locus_tag="KRL22_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1271375.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILIFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTVFCIC
                     KYKNRYKYM"
     gene            35163..35876
                     /locus_tag="KRL22_000862"
     CDS             35163..35876
                     /locus_tag="KRL22_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271376.1"
                     /translation="MDTYFNKKILLVDDEKDIVDLIEEVLTNDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIVFRVKAQLRRQQYQSIVPSDSEVIKVGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMDQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(36153..37691)
                     /locus_tag="KRL22_000863"
     CDS             complement(36153..37691)
                     /locus_tag="KRL22_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1271377.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGAGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINKDTTISLYLHTAFEKLYKIEKEMN
                     LLYQKSAISGNEQYLIKASDYQEQLIANNFYSIDNEINKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSDYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            38574..39029
                     /locus_tag="KRL22_000864"
     CDS             38574..39029
                     /locus_tag="KRL22_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH1271378.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            39078..39662
                     /locus_tag="KRL22_000865"
     CDS             39078..39662
                     /locus_tag="KRL22_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBH1271379.1"
                     /translation="MKILVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(39667..39990)
                     /locus_tag="KRL22_000866"
     CDS             complement(39667..39990)
                     /locus_tag="KRL22_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1271380.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            40142..40660
                     /locus_tag="KRL22_000867"
     CDS             40142..40660
                     /locus_tag="KRL22_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1271381.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYEAGTPESPDRHNKTR
                     LPLNEIVSYETL"
     gene            41154..41897
                     /locus_tag="KRL22_000868"
     CDS             41154..41897
                     /locus_tag="KRL22_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018211375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271382.1"
                     /translation="MNKIIEVINLQKSYDTFKAVKRINFYVEEGNLFALLGANGAGKS
                     TTIDILCTLLDYDSGEVIIDGHKLSVEDNKIKEKIGVVFQESILDPLLTVRENLTFRA
                     KFYIKNKGKVEQIVHESALSVGAMEFIDRPYGKLSGGEKRRVDIARALLNTPKILFLD
                     EPTTGLDPEARKCVWDTILKLQKQYGFSIVLTTHYMEEASKADYIVMLDYGTITAKGS
                     PHELKHKYRANNLDDVFLNIVRNRGEKNV"
     gene            41890..42747
                     /locus_tag="KRL22_000869"
     CDS             41890..42747
                     /locus_tag="KRL22_000869"
                     /inference="COORDINATES: protein motif:HMM:NF013245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1271383.1"
                     /translation="MFNLAQRNIMIFLRNKRGVFSSFLGAIIVIGIYVIFLGENLKEG
                     YPNIKDIDILMNSWAMAGIISVVSVTTTMGSFGITVLDKELKRTKDFYCSPIKTRELV
                     GGYILSSYLIGIIMSIFTFVLAEIYIVLSGGQILSMFSIIKVIGVILLTVLSSSAMLF
                     FIINLLNSIDTFATASTIIGTLIGFLTGIYIPIGSLPQAVQTIIKVFPISHGTVLLRQ
                     IITDSPSKVVFVDSTNALTAFNEHMGVTFGSIGSLSETSIHIMFLVISSIIFYFVTII
                     MVSKKKTKN"
     gene            42883..43242
                     /locus_tag="KRL22_000870"
     CDS             42883..43242
                     /locus_tag="KRL22_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013658047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBH1271384.1"
                     /translation="MIKLIFNIKMQRESLIAYKNEQLYRINPLDIYYFESIDNHTYLY
                     CKNDVYEFKKKLYQIEEIFSNGDFLRISKSVILNLTKIDSIVPAFNGRFEAILDNGEK
                     TIISRQYVPMLKKKLRI"
     gene            43258..43701
                     /locus_tag="KRL22_000871"
     CDS             43258..43701
                     /locus_tag="KRL22_000871"
                     /inference="COORDINATES: protein motif:HMM:NF022896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 family protein"
                     /protein_id="HBH1271385.1"
                     /translation="MNLINTLKNVVRYFCMITTGVLISVFTSCLVFSPEETFNISIFQ
                     QILLVALVTSLSTLIFYSKRELGRKEMIIRQVIHIIFIFVFVLWFSFKSKWVDGGHIF
                     QALFIALSIFIIYICITLATCKRDKKESILLNKGLKEYRKNKINK"
     gene            43859..44317
                     /locus_tag="KRL22_000872"
     CDS             43859..44317
                     /locus_tag="KRL22_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1271386.1"
                     /translation="MEIIDYIEENLTENLNLDKIADIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQKFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            44314..44898
                     /gene="clpP"
                     /locus_tag="KRL22_000873"
     CDS             44314..44898
                     /gene="clpP"
                     /locus_tag="KRL22_000873"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH1271387.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            45210..46286
                     /locus_tag="KRL22_000874"
     CDS             45210..46286
                     /locus_tag="KRL22_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1271388.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDFTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            46353..48356
                     /gene="bclA3"
                     /locus_tag="KRL22_000875"
     CDS             46353..48356
                     /gene="bclA3"
                     /locus_tag="KRL22_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HBH1271389.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGFGVTGPTGPTGATGI
                     GITGATGLIGPTGATGATGATGPTGVTGATGAAGLIGPTGATGATGADGATGATGATG
                     ATGLTGADGLVGPTGATGADGLVGPTGPTGATGVGITGATGATGPTGATGATGADGVA
                     GPTGATGATGNTGADGATGPTGATGPTGADGLVGTTGATGATGLAGATGATGPIGATG
                     PTGADGATGATGATGPTGADGLVGPTGATGATGATGATGPTGPTGASAIIPFASGIPL
                     SLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNAAGTLTNFAFSMPRDGTITSIS
                     AYFSTTAALSLVGSTITITATLYQSTAPNNSFTAVPGATVTLAPPLTGVLSVGSISSG
                     IVTGLNIAATAQTRFLLVFTATASGLSLVNTVAGYASAGIAIN"
     gene            48525..49286
                     /locus_tag="KRL22_000876"
     CDS             48525..49286
                     /locus_tag="KRL22_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBH1271390.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKIGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            49595..49873
                     /locus_tag="KRL22_000877"
     CDS             49595..49873
                     /locus_tag="KRL22_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271391.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            50166..50741
                     /locus_tag="KRL22_000878"
     CDS             50166..50741
                     /locus_tag="KRL22_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HBH1271392.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            51180..51890
                     /locus_tag="KRL22_000879"
     CDS             51180..51890
                     /locus_tag="KRL22_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271393.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            51884..53200
                     /locus_tag="KRL22_000880"
     CDS             51884..53200
                     /locus_tag="KRL22_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1271394.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIKNND
                     ICSIFANSLDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            53212..53352
                     /locus_tag="KRL22_000881"
     CDS             53212..53352
                     /locus_tag="KRL22_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBH1271395.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            53411..53992
                     /locus_tag="KRL22_000882"
     CDS             53411..53992
                     /locus_tag="KRL22_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBH1271396.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNILVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNSDQ"
     gene            54249..54623
                     /locus_tag="KRL22_000883"
     CDS             54249..54623
                     /locus_tag="KRL22_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271397.1"
                     /translation="MNLKKKIKKLGVTFAIGTIIVSSLGTSVFADEVSTYALISKAFS
                     GKNNIISSSVYTSGSRTFKTTDSQGGFSCRLTERFSGSSPDRIVKRHEANASSKVSLS
                     GGTYYIRYEGSTNNAKTYATLN"
     gene            54706..56415
                     /locus_tag="KRL22_000884"
     CDS             54706..56415
                     /locus_tag="KRL22_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271398.1"
                     /translation="MSSIKVISDFITKIIRKNILFAITIIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTKMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKVNSENIKFNKKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSCMAYKINLSSKNNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            56430..57302
                     /locus_tag="KRL22_000885"
     CDS             56430..57302
                     /locus_tag="KRL22_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1271399.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLIDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            57303..58091
                     /locus_tag="KRL22_000886"
     CDS             57303..58091
                     /locus_tag="KRL22_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271400.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(58187..58990)
                     /locus_tag="KRL22_000887"
     CDS             complement(58187..58990)
                     /locus_tag="KRL22_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013841681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HBH1271401.1"
                     /translation="MEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDSVLYLLELGVN
                     PDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGYASDIRMQKTF
                     QHFLDTQYTDGGWRCNKFNFGRGPETEYSNPLPTLNILNAFRFSNYLNKESKLDKAVD
                     FLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNCAKKDNRFLEAL
                     KILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLEK"
     gene            complement(59075..59704)
                     /locus_tag="KRL22_000888"
     CDS             complement(59075..59704)
                     /locus_tag="KRL22_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HBH1271402.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMI
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
BASE COUNT        20980 a         8204 c        11084 g        19503 t
ORIGIN      
        1 gcacagagct tagtgcttat ggcgattgtg gttatcggta tctacttagg gctcaagcgt
       61 gagttttcaa aacttattgg cttcttggta gttgccctta ttgctgtcgg cttagtattc
      121 aacgctagcg gtgtgaaaga tgtactgtta gagctgttca ataagattat tggagcataa
      181 cgaattttat tgttgctgta atatgagaat gttataatgt gggtacgata aattattttt
      241 tgaaaggaat aaaagtgatt atgatttcag atgaaatgag agtggatatt ttacatgcag
      301 tattcataaa ccaaaatttt attaaagatg aagaaaattg taattatgaa aaatacttgt
      361 tggaattagt taataaatca atatatttta gagaaaaatc aaattttgca gaatatgtac
      421 cacctaaatc tgaaaatcat ggagaatgtg attgtaactc acctaattat caaatggact
      481 ttaaattact tgaaatcaca acaagacttc atgcttcaaa agaacttact ggtcaaatac
      541 agaaattctg tgatggtgta attggtaagt gtccaccgag aagaccaaat acacaaatga
      601 ctgtaactag gttatttgct tcgttgcggg attatgattg tgaaagttta cattcttgtc
      661 ttacagagaa atatgagtat ggaacgattg aatttgatat acaaacctat gtgaaattgc
      721 ttactttcaa gaaaaactta tttttctttt ttccatacaa gtttagtttt aatacttgtt
      781 ataactttaa atatgcttta gacagtataa gaattgcttt agaaaaagat tttagagagt
      841 caaatctttt tagagaaaaa tactatgcag agtatgatac tttcttagca tatatctatg
      901 aagataatct gataataagt aaatttgaac aagacggcaa gttacaaatg attgattgta
      961 tatatttatt taaaagtcaa acatacagta aactttacga gtacacatgg taaatcagtt
     1021 acacttaaac aaattcatac ttacacacaa agcagttagt cttaggattg actgcttttt
     1081 tcttacctaa atttcagatt ggagtgatga aatgaacgat atttttaaag atatgcaggc
     1141 aaaagtcggc tgtgaataca tttccgacct gccctcttac aagcgtaagg tgtggcatga
     1201 aatgaaacgg ctgaaccctg ccgactatga agaaaaacag ttggaagatt tttctaaata
     1261 tgtgtttggt atgtcatacc agaccttaaa agatgtgatg aaacaacaga aaggacgtga
     1321 ggaacaatgc aggaaacaag ggtactggtg gaaacgggaa gaacaaatgg cgaagaaaca
     1381 acatcatact ggtttgactt accgatagat gttgcagagt ttgaagaaaa gttaggtgtc
     1441 ggtgcagaaa gtcaagatta ccgcattatc gaaaaggtgt tgccttatgc tgatgaagtc
     1501 cacgaacaca ccagcgtgta ccagcttaac gaattagatt ttatgtaccg ccagctatca
     1561 gccgatatgc aggaagaata tgtagaactt cttaccgtgt ttgagaactt agaagcactt
     1621 tatatttgca ggaacgtgat taccgtttat cacgactgta aaagcatgat agatgttgca
     1681 aggcaaaagc tgatgaacga cccgacattc aaacatttat ccgaggactg tcaagcatac
     1741 tatttcgatt ttgaagccta cgcttctcac ttacttgaaa acaaacgcta tcttgtaacg
     1801 gaaaacagta tctttgaact gccagaatag gaaatgaggt ggtgcttatg attgatgata
     1861 tggcggttta tattgctaat cttggcagat acaatgaggg atatttagtc ggtgcgtggt
     1921 tcactttccc tattgacgag gaagatgtaa aagaaaaaat cggcttgaat gaacagtacg
     1981 aagaatacgc tgtccatgat accgacaact ttcctatcga cataggggaa tatgtttcca
     2041 ttgaagaact caatgaaatg tatgaaatga tagaggaact tcccgactat atcgtagagt
     2101 gtctggacga atttatcagc cactatggga cgctggaaga agtcgtggaa cataaggacg
     2161 atatttattt ttatcccgat tgtgaaacca tgacagatgt tgcctactac tacatagacg
     2221 aattgaacgc acttggggac attccagcta acttacagaa ctatattgac tatgaagcct
     2281 acgggcgaga tttggatatg ggtggtcgat tcattgaaac aagccgaggt atctgtgaga
     2341 taccatatta acgctggaag atcagcaaca agcattgttg ctactgacag cgtatttctc
     2401 tttaagggac agtctgaaaa tggctgtcct tttctctttg aagaacttac gaaaggggct
     2461 gaaagaactt gaaaaagatt aaaagctaca cgggtatctg gaacgtggaa aaagtcttat
     2521 atgcaatcaa tgactttaac ttaccctttc ccgttacctt tacacagatt acatggtttg
     2581 tgattacgga atttatcatc attctgtttg gggatatgcc cccactttcc atgattgagg
     2641 gagcatttct caaatacttc ggtattcccg ttgctctcac ttggtttatg tcgcagaaaa
     2701 cctttgacgg aaagaagccg tacagctttt tgaaatcaca gataacctat gccttgcgac
     2761 ctaaaatcac ttatgcagga aaagccgtaa aactgcataa gcagatattg aatgaaacaa
     2821 tcacggcagt aaggagtgtg aactatgttc ccgataaaat atattgacaa taaccttgtc
     2881 tggaacaagg acaatgaggt gttcgcctac tatgagctga taccgtacaa ctattctttt
     2941 ctatccgcag agcagaaatt tatcgtgcat gacagttttc gacagctaat cgcacagtcc
     3001 cgtgagggaa aaattcatgc gttgcagatt gccacagaaa gctccattag aagtatgcag
     3061 gagcagtcaa agaaactggt aacgggcaaa cttcgtgagg tggcagtcca aaaaatagac
     3121 gaacagaccg aagcgttagt atcaatgatt ggggacaatc aagtggacta ccgctttttt
     3181 cttggcttta agctcatggt tacggaagaa cagctcaatc tgaagaacat caaaaaatcg
     3241 gcatggctga cgttcaagga atttcttcat gaagtgaacc acacgctgat gaatgatttt
     3301 gtttccatgc cgaatgatga aatcaaccgt tacatgaaaa tggaaaagtt actggaaaat
     3361 aaaatctccc gtcgctttaa ggtgcgtcgc ttggaaatcc atgattttgg gtatctcatg
     3421 gaacatcttt acggcaggga cggtatcgcc tatgaagatt atgagtacca gctaccaaag
     3481 aagaaattga agaaagaaac gctgataaaa tactacgacc ttatccgtcc gacaaggtgt
     3541 gtgattgagg aaagccagcg gtatttacga ttggaacatg aggacaagga aagctatgtg
     3601 tcctatttta ccgtcaatgt aattgtcggg gagttggatt ttccgtcctc tgaaatcttc
     3661 tatttccagc aacagcaatt cacattcccc gttgatactt ctatgaatgt agaaatcgtg
     3721 gagaaccgta aggcattaac gacagtccgc aacaagaaaa aggaattgaa agatttggat
     3781 aatcacgcct atcaagcagg aagtgaaacc agctcaaatg tggtggacgc tttagacagc
     3841 gtggacgagc tggaaaccga tttagaccag agcaaagaaa gtatgtataa gttaagctac
     3901 gtcatacggg tgtctgcacc cgatcttgac gagctgaaac gccgttgtga tgaagtcaag
     3961 gacttttacg acgacctcaa tgtaaaactg gtgcgtcctg ctggcgatat gttgggactt
     4021 cattctgaat ttttacctgc cagcaagcga tatatcaatg actatgtgca gtatgtaaag
     4081 tcagacttct tggctgggct tggttttggt gcgacccagc agttagggga aaacacgggt
     4141 atctatatgg gctattccgt tgatacggga agaaatgtgt acctgcaacc gtctttagct
     4201 tcgcagggag taaaaggcac agttactaat gcccttgctt ctgcttttgt gggaagtctt
     4261 ggcggtggaa agtcattctg caacaatcta cttgtatatt atgcggtgct gtttggcggt
     4321 caagcacttc tgttagaccc taaaagtgag cgtggcaact ggaaagaaac gctcccagag
     4381 atagcccatg aaatcaatat cgtaaacctt accagcgaca aggacaatgc aggacttctt
     4441 gacccatttg tgattatgaa gaatgtgaaa gacgctgaaa gtctggcaat cgacatctta
     4501 acattcctta cgggtatttc ctctagggac ggcgaaaaat tccccgtgtt acgaaaagcg
     4561 gtgcgttctg ttacccagag tgaaaataga ggactgttac acgttattga ggaattgaga
     4621 aaagaagata ccgctatctc acgcaatatc gcagaccata tcgacagctt cacggactac
     4681 gactttgcac acctgctgtt ttcagacggg acggtagaaa atgctataag ccttgataac
     4741 cagctcaata tcattcaagt agcagacctt gtactgccag ataaagatac cacttttgag
     4801 gaatacacga ccattgaatt attgtcggtg tctatgctga ttgtgattag tacctttgcc
     4861 cttgatttta tccattcgga cagaagcatt tttaagattg tagatttgga cgaagcgtgg
     4921 gcgttcttaa atgtggcaca aggcgaaacc ctatcaaata agctggttcg tgctggacga
     4981 gctatgcagg caggcgttta tttcgttacc cagtctgcct atgacgtgtc aaaggaaagt
     5041 ctgaaaaaca atatcggttt gaagtttgca tttcgttcta ctgacatcaa cgagataaag
     5101 cagaccttag aatttttcgg tatcgacaag gacgacgaaa acaaccagaa acgcttgcgt
     5161 gatttggaga acggacaatg tttattgcag gacttatacg ggcgtgtcgg tgtggtgcag
     5221 atacacccag tctttgaaga attactacac gcctttgata ctagaccgcc cgtacagaga
     5281 aatgaggtgg agtgatgaaa gaaaggatac agagtgcgtt cacaaaaagg aagatacttc
     5341 actttctcaa aatggctctg ttcgtggtgg cactttccct tatcctgctt tcacttctgg
     5401 ggacggtggc tcatgcgacg gggcttgtgg acgataccat aaacgcagaa aatctatatt
     5461 caaaatatcc gctttccaac taccagcttg attttttcgt cgataatagc tggtcgtggc
     5521 ttccgtggaa ctggctggac ggtatcggaa aatcggtaca gtacgggctt tactgcatta
     5581 ccaactttgt ctggacgata agcctttatt taagcaatgc aacgggctat gtggtgcagg
     5641 aagcctataa acttgatttt attaacgata tggcagacag tatcggaaaa agcatacaga
     5701 cccttgcagg cgttactgag aacggctttt cttctacggg cttctatgtt ggtttcctgc
     5761 ttcttattat cttagtggtg ggaatgtatg ttgcctatac gggactgata aaacgggaaa
     5821 ccagcaaggc acttcacgct gttatcaact ttgtggtggt gttcgtgctg tccgcttcgt
     5881 ttattgccta cgctcccgac tacatcaaga agataaatga attttcatca gacatcagta
     5941 ccgcttcgct tgatttggga acaaaaatca tgctccccaa ctctgacagc gagggcaagg
     6001 acagcgtaga cttgatacgg gacagcctat tttctattca agtacaacag ccgtggctac
     6061 tcttacagtt tggaaacagc aacgcagagg aaatcgggac agaccgtgtc gaagctctcg
     6121 tatcggcaag tccagaggac gaggacggaa agaccagaga agaagtcgtg aaaacagaaa
     6181 tcgaggacaa cgacaacaac aatctgacga taccgcaggt ggtaaaccgt ttaggtatgg
     6241 tgttcttcct cttgttcttt aatcttggta ttacgatatt tgtattcttg cttacgggta
     6301 tgatgttgtt cagccagata ctttttatta tcttcgctat gtttttacct atcagctttc
     6361 tactttccat gataccgagc tatgaaagca tggcaaagca ggcaatcgtg agggtattta
     6421 ataccataat gacacgggca ggaataacgc tcattgtaac ggttgcgttt agcatttcca
     6481 gtatgtttta taacatatcc acggactatc cgtttttcat ggtggcgttc ttgcagatag
     6541 tatgtttcgc tggtatctat atgaagctgg gcgacttaat gagtatgttt tctctcaacg
     6601 ctggcgacag tcaaagcatg ggacgcagga tattccgcag accgtatctg ttcatgcgac
     6661 atcgggctag gcgtatggaa caccgtattg caagggctgt aagtgctggc ggtatttcgg
     6721 gcggtgtggc tggtgcggta gctggaagtg ccgttgctgg caagagagcc gaaagaaaaa
     6781 atacggcttc taaagaaaat cggggcaata ccacttccag tatgggacag cgtgcaggct
     6841 caaaggtggg tgctgtctta gatacgaaaa ataaagtgaa agacaaggca aacgctgtca
     6901 aagagaatat caaggatatg cccacacaga ccgcttatgc ggtgtattcc gcaaaggaaa
     6961 aggcaaagtc cagcgtgtct gatttcaagc gtggtatggt gcaggaacag cagtccagac
     7021 agacgggacg cttggaaaag caggaacagc ataagaaaag tatcgctgtc aagcgtatgg
     7081 agcttcaaaa ggcacaagaa gcaaggcagg cacagcgaaa ggctgacgga tcagcgacaa
     7141 cgggagctac ccgtccccat gagcgaccag ccacagcttc aaccgtttca aagacgggtg
     7201 cggaaaaaat gcaggaagtc aaacgccctg ccacaactcc gactacgaaa gcaagcgaac
     7261 cagttaagac aagcggtgtc aaagaacgtc cgctatcttc tagtactcct gacgggaaag
     7321 cgacccaatc gacatatagg cagaatgtag aaaaagttac cgtgtcaaag gaaacacgcc
     7381 agaattacac caaagaccgt aggacaaagg ttcagcagac ccagactgtc cagaagaacc
     7441 agcagaccac agagaaaatc cgtaatcttg taacgaaaaa aggacagaag aaaaaatgaa
     7501 actgaaacat atcgctatca ttggcagtct gtttcctatt ctcttttctc tggtgctttt
     7561 ctttggggtg ctgattagtg cggacagcga cgacgaaaac agcaactttt cttctggcat
     7621 tacgggtatg aacttatccg cagaagtttt gaaacatcag cctatggtag aaaaatacgc
     7681 cagagaaaac ggtatctccg agtacgtcaa tgtactactg gctatcattc aagtagaaag
     7741 tggcggtacg gcagaagatg ttatgcagag ttcagaaagt cttggtttac cgcctagttc
     7801 cttagatacg gaaagctcaa tcaagcaggg gtgtaagtat tttgcgtccc tgctttcttc
     7861 ctgcaaaaat caaggtatcg acgatttgaa tgtagcgata cagtcctata actatggcgg
     7921 tggctatgtg ggctatgtgg caggaaacgg aaagaaacac acttttaatc ttgcagagag
     7981 cttcgcccgt gagaaatcgg gtggaaagaa agtaacctac accaacccga tagccgttgc
     8041 gaagaacgga ggctggcggt atggctatgg aaatatgttc tatgtggaat tagtcaatca
     8101 gtatttaact gttccgcagg tatcgggaga gctggcacaa aaggtaatga atgaagcgtt
     8161 gaaatatcaa gggtggaaat atgtgtttgg tggttcttct ccaaccactt cctttgactg
     8221 ttcgggactg acgcaatggt gctatggaaa agctggtatc tccttaccga gaacggcaca
     8281 agcccagtat gacgctaccc aacatcttcc actctcgcag gcaaaggctg gcgatttggt
     8341 atttttccat tccacctata acgctggttc gtatgtaacc cacgtcggta tctatgtggg
     8401 aaataatcag atgtaccatg caggcgaccc gataggatat acagacctaa gtagtagtta
     8461 ctggcaacag cacttaatcg gtgcaggacg agtaaaacaa tagaaaggac ttgaaaaata
     8521 tgtttaagaa gaataagaaa cagacagaaa atgtcaaaga aaaaaaggta cgtactgtca
     8581 aggtaggcac acataagaaa accgtgattg cattgtgggt ggtgcttatt gcaagcgtga
     8641 gctttggagt atataagaat tttaccgcta ttgaccagca cacgacccat gaaaaagaag
     8701 tgattgagct tcgcttgcag gacaccaacg ggatagaaaa tttcgtgaag aattttgcaa
     8761 agtcctatta cacatggagt aacagcaaag aagcgattga cgcaaggacg caggcaatca
     8821 gcggttatct gacaaaggaa ttgcaggact tgaatatgga taccattaga acggatatac
     8881 cgaccagctc tgccattaca gatgtgattg tatggagcat tgaacagtct ggaacggaca
     8941 ctttttccgc tacctacgaa gtagatcagc agataaaaga gggggaacag acaacagcgg
     9001 ttaaggcaac ctataccgta aaagttcatg tggacgctgg cgggaatatg gtaattattc
     9061 agaaccctac ccttgcacca gcaatcgaga aatcagacta tgaaccaaag acaccagaag
     9121 cagacgcaag tgtagacgcg gataccataa atgacgctac tgcatttctg gaaactttct
     9181 ttaagctata cccaacagcc acagaaaagg agcttgctta ctatgtgtct ggaaatgtgc
     9241 ttgagtctat cggcagggac tacctctatt ctgaattggt aaaccctatc tttacggttg
     9301 atggggacaa tgtgaaagtc aaggttgccg tgaaattcat tgataatcag acaaaggcaa
     9361 cacaggtatc gcagtttgaa ttagtgctac ataaggatag caattggaag attataggat
     9421 aattattgaa agcgtgcatt tctttaggaa tttgcacgct tttgttaaga gcattattct
     9481 ttatatttat gaaagagatc ttaaacaaag tattaatggc ttcgcaaaat ttttttctta
     9541 atatatttgg attagaaaaa gcgcatctta attgtagact tactatacat atgaattatg
     9601 ccagtcaacg tatttaaaat ttatgttgtt ttattttgtt gtaaatcgca agaatagata
     9661 agagtaatca atggtgaagg ggaattatta aaaatactat tggtttcttc tgtcccgttc
     9721 caatttgcgc attgtatttt ttcataaatt acagagtggt caattatgta gttcagatat
     9781 tcaatacaaa ctaattgtat tgtttttaca ctcgttttcc atactgccac ttttgtcatt
     9841 ctatcactca taatacaaat attattatga gcaacttttc taagtagttc atttaaattt
     9901 gatacatggt caaggtgaaa accaagaaga agtttgtcag cactcatatg tgtcaagggg
     9961 aaatgcctat ttatgtgcga gagagctatg agaaaatgct tgccgtatcc atccgtgctc
    10021 caaatttaga aggaatggtt gaaaactttg ataaggattt atctcaccct aacgagacgg
    10081 atttgatcga gctgaaaaat gccatatcaa agtaaattgc aagaaaaaag caagaatata
    10141 aatatagcat tttcagaaca ctgtgttaaa atgttattac ttatacttat aaaggagggg
    10201 atgtttcgtg tcaaaagcaa cactatttga tagtcgtatc aaaaaatacg catactgtag
    10261 aacatcagaa atttatcgag acattggctc atctccggat ggtttatcca ttgagcaaat
    10321 cggttcaatg cgggagaaat acggagcgaa cagcttcaat gggcggaaaa atgatacgac
    10381 gatgcaacgg ttgagacggg catttattaa cccgtttcat gtgattcttt ttgttctggg
    10441 cattgtttct cttgttacgg atgttttcgt agcatccaat tttgcgagaa atgctactac
    10501 cgccattatc atcttttcca tgatcgtaat tagtggcgga attcgtctga ttcaggagct
    10561 gcgagctaag agcgctgctg ctcagcttga tcgcctagtt catgaaagcg tcacagtgag
    10621 gcgtgatgga aagttaatag agattcctgg cgaagaatta gtggtagggg atattgtact
    10681 attctctgca ggtgatcgtg ttccggcgga tatcagattg acgaagatta cggatctctt
    10741 tatctctcag gctgcgatta ctggcgagag cgccatcatt gaaaagagct gccgaaaact
    10801 cagttacgga gagcaggata cactgactca gcttgaaaac ctcgctttta tggcaaccac
    10861 agtcatcagt ggaaaagggg aaggcattgt actggcagta ggcaaagata ccctgtatgg
    10921 aggatttacc aaaccggatt ctgatgataa aaattccttt aaaaaaggag ccgattccat
    10981 cgcctgggtg atgatacgtt ttatggcgat attagttccc attgtattta tattactggg
    11041 gattactgat ggaaaatgga tggaatcctt tgctttcgct ctgtcagttg ctgtaggtct
    11101 gatgccggaa atgcttccta tggttattac agcctgcctt gccaaaggaa gtcttgctat
    11161 gagcaaaaag cagaccatta tcaaggatat taatgccatg cagagctttg gtagcatgga
    11221 tgtgctttgt atggataaaa caggaacact taccaatgaa agcatcctgc tggaatatta
    11281 tatggatatt tttggaaatg aaaatgcaga ggttcttgat cttgcttatc tgaatagctg
    11341 ctatcattct ggtgtctgca ataccattga taatgccatt cttgcctgca ataccatgcc
    11401 agggcgggaa gcccattacg caaatcttct gacaaaattc caaaaagctg atgaaattcc
    11461 ctttgactat gctcgtaagt ttgtcagtac acttgtacag gatagcaatg ggaatagtca
    11521 gcttattatg aaaggtgata ttgaacatat attctcacgc tgcaaccatg tagaatatcg
    11581 tggaaaactt ctccccatgg ggcaggatgc gagacagagt gtatcttctg tagtaggtga
    11641 aatgttacag gacggaatga aggtcattgc ggtggcacga aaaaatgtgg gagcgcaaaa
    11701 gaaaataact cctgatgacg aatggggcat gactctagtt ggctatctat ccttctttga
    11761 tgcaccaaag cagacagcaa aggagtctgt aactgcactc aaaagattaa aagtgatccc
    11821 taagattctg acaggggacc aggcagcgat tgctgtgtct gtttgccgcc gtgtgggtat
    11881 ttatacagag cgtatcttaa ctggtactca actggatgaa atgacagact gtgaacttaa
    11941 aaaggctgtg gaacatactc atgtttttgc agagcttact ccgggacata aggtgcgtct
    12001 tgtctctgct atgcaggata atggtcattc cgtgggattt cttggtgatg gagtcaacga
    12061 cattccggca ctgaatgaag caaatgttgg aatctctgta gatacggcag tggacgcagc
    12121 gaaagatgct gccgatgtgg ttttgctgca aaaggacttg aatgttttgg aggaaggtgt
    12181 aatggagggg cgaaaaactt ttaccaatat gctgaaatat attaaaatca ccgctagctc
    12241 taactttgga aatatttttt ccatcatttg tgccagtgcc tttttaccgt tcctgcctat
    12301 gacttcaatt cagattctgc ttttgaatct gctgtatgat acgttgtgta ttgtgcttcc
    12361 ttgggacaat gtagatgagg aagagatact gtccccaaga gattggtccg gcaaaacact
    12421 gagacagttt atgctgtctt tcggaccgat cagttctctg tttgatattg tcaccttcct
    12481 atttttgtat tatttcctat gtccgatgct atgtggaggg gcaacttatc tgcagcttac
    12541 agatccttca ctgcaacttc agtatgtagc actgtttcag acgggatggt ttttggaatc
    12601 tatgtggaca caggttttga ttttacattt tctgcgaact tccaagattc cttttttcca
    12661 gagcagggca tctgcaccgg tcatttctat aactctagtg gggattattg cttttacttc
    12721 ccttacattt gtcggcggtg cgtcgttgtt tggactgacg aaattacctc tttggtattt
    12781 cgtattttta ctgctggtgg tatctctcta tatgctgctg agttcagtag ccaaatattt
    12841 ttataagaaa aaatatcaag agttgattta agaggaggca ttcatgatga aaaagaatat
    12901 tagttatatt ccgatggatt cggctcttga aatctggcta ttagaaaaac tactaagaga
    12961 tccaccggac agtgattgtg cgaaggattt actttctggt attcaggaga tgattcgtgg
    13021 agaggtatct tcgttattgt taggagcatc agaagaaagc gattggccag tgggtactct
    13081 gtcagataga atcctggcag gggatctgga aatttatcca agaggcagaa aagtactgat
    13141 aaaaggttct gaagtcaacc tgactccaaa ggaatttgat attttgtact ttcttgtcca
    13201 gaacaaaggt gaagttttta caaaggaaca gatttatcgt gccgtatggg gggaagatta
    13261 tattctggat aacagcaaca ttatggcttt tatccggaag ttgcgaaaaa agattgaacc
    13321 tgctccggat tgtcccacat acattttgac catctggggt attggataca aatttaatga
    13381 tcagatatga caaagacgga ctaagaccat tttcggtttc agtccgtcta ttttcttagc
    13441 aaatcgcaag aaaatcgcaa gactttagcc ataggattgt atttgaattt tttatatact
    13501 gttagtagtt aaagggaggt gtttcatatg ttttacacag attttatttt gagaattgcc
    13561 ctctccttaa cacttggatt tcttattgga ttagaacggc aattgactgg tcatcctgca
    13621 ggtattcgta tcaatgtgtt aatctgcatg ggtacaagtt tctttacctt gtttcctatg
    13681 ctctacggtt cggatcaggt attccgtgtc ggaagcagta ttatatccgg tgttggtttt
    13741 ttatgcagtg gtgttatttt caaggacaga gggacagtac gtggaatgaa taccgctgcc
    13801 accttatggt gtactgcagc cattggaatt cttgcaagta cgggaatgta tgcaatggcg
    13861 atcaccgccg ctactatttt aattggttcc aacctgattc tacgtccctt tgcaagaaag
    13921 tttcacccaa ttacttccag tgatgaatct gaaaagcagt atcgtatttc ggttacatgt
    13981 caggaaaagg cagagcagga tatacgctta ttgctgatta acagcaattc ctgtaagacg
    14041 ctctttttga acaatctgga aagcggtgat gtggttggtg acaaggttga gattgtcgca
    14101 gaatactgtt ctgtcggaaa atccaaaaac aatattttag aaggaatcgt tgggcaggta
    14161 ttggtaattc cggaagtgat tagtgctggt tgggaggtgt tgtgagtgag gagagaaatc
    14221 gaagatttga aacgagcaat tctttttgct ttctaccctg tatttacaat cttatgtagc
    14281 tatttgggtt ggaatttctt tgaacaaaga atggcaatct ttaagatatg gtatcaggtg
    14341 agtattgtga tctggtttat tcttgctgtt actattattg tgctcttcat taaacttctg
    14401 aagctgacga aactaagaaa caggtttaag cactgaaagg aggaacaaac gatggatttt
    14461 acatgtatct tttttggaat tttatttact cttgcaggct tttggctggc ctttggaaaa
    14521 ggatatcgtc atctttccct gtggaaaaat atgccgcagg aggagaaaga taaaattaat
    14581 attgtcccgc tttgtcgtaa tgttggagaa atgattgcgt taaatgggat tatattctta
    14641 atgaaaggat ttttgccggg attttcaaac cactggtttg tatttgcaat aatcgcatgg
    14701 ctgattgttg ccggctttga tgtctggtat atcgaaaaaa gtgtccgcta tcgtaaccaa
    14761 taatccacat tgaggtttca catagatatt tttttaagat tgtgaggtga aagacatgga
    14821 ctctgatgtc agtccacgaa ggcagagaat attatatgag aagttggaga ttccgtgtcg
    14881 cccatataat attccttgcc cctatgaaaa ttcaaggagg taagaccaat gaacaaaaaa
    14941 gaaaatcgta tggctattcg tcagactgta gaaaaagcag tcatccgtga cgaacagaac
    15001 caccgcattc aatttgcggc aaccaatcct attaaagacg ttttaaaaaa acttcatacc
    15061 acacttcgtg gcttagacgt agatgaagta tccgtaagtc gtgctaaata tggtaccaat
    15121 aaagtcactc atgaaaaaaa gaaatctctg gcaaaacgac tggttggcgc atttatcaat
    15181 ccatttaccg ccattttatt ttgtctggct ttagtatcca caattacaga tatgattttt
    15241 ccgtattttt ctctgtttgg cagtgtgcca gaggactttg attccctgac tgttgtaatc
    15301 attttaacaa tggtattcat ttccggtacg cttcgttttg tacaggaatc cagaagcgga
    15361 aatgcagcag agaaattgtt agccatgatt acgaccactt gtacagttac tcgtagaaac
    15421 tatgaaaaaa aagaacttcc tatggatgat ttggtggtgg gagatattgt gcatctttct
    15481 gctggagata tgattccggc ggatgttcgt attttggatg cgaaggattt gtttgtcagt
    15541 caggcaagtc ttactggtga gagtgaacct attgaaaaaa cacccaatgt aagtgctcag
    15601 aaagaaagcg tgactgatta cacaaacatt gcttttatgg ggagtaatgt aatttctggt
    15661 agcgcaacag ctgttgttgt ttgtgttggc gatcatactc tgtttggctc tatggcgtcc
    15721 gcagttgctg gagaagcggt tgaaacaagc tttaccaagg gtgtcaatgc cgtttcttgg
    15781 gtattgattc gttttatgct cattatggtt ccgctggtgt tctttgtcaa tggtatcacc
    15841 aagggcgatt ggttggcggc cttcttattc ggcgtttcta ttgctgttgg tttgacacca
    15901 gaaatgttgc cgatgattgt aacaacctgt cttgcgaaag gcgctgtttc catgagcaag
    15961 aagcagacaa tcgttaaaaa cctcaattcc attcagaact tcggtgctat tgatattctc
    16021 tgtactgaca agactggcac gctgacccag gataaggttg tgctggaata ccatctgaat
    16081 gtaaatggcg aggacgatac gcgagtactg cgtcacgctt acctcaatag ttacttccag
    16141 actggctata aaaacctgat ggatttggca attatccata agacggagga agaggaagcc
    16201 gcagattcgc gtctcattga cctgtctgaa aactatgtga aagtagatga gattcctttt
    16261 gacttcacac gtcgtcgtct gactacagtg gtacaggata ataagggtaa gacccagatg
    16321 gtaacaaaag gtgctgtgga agaaatgctc tctatttgtg cgtttgcaga gtgtaatgga
    16381 ggagtgcagc ctctgactga tgacgttcgt tacagaattc tggagacagt ggacaatctt
    16441 aacgataagg gattccgcgt actagctatt gcacagaaga gtaatccttc cccaatcggc
    16501 gcatttggtg ttaaagatga gtgtgatatg gtactgattg gatatctggc attccttgat
    16561 cctccaaaag aatctactgc ggatgctatt aaagctctga aagaccatgg tgttataacc
    16621 aaaattttga caggtgacaa cgacaaagtg actcgaacta tctgcaagca ggtgggatta
    16681 gaggttcgca atatgcttct cggttctgat ttggaacaaa tgggcgatgc agagcttgca
    16741 agagtggcag agtctacaga tgtatttgca aagctaaccc ctgatcagaa agtccgtgtg
    16801 gtttctgttc tccgtgaaaa tggtcatacg gtcggtttca tgggtgacgg tattaatgat
    16861 gctgcagcta tgaaagccgc cgatattggt atttcggtgg ataccgccgt ggacgtggca
    16921 aaagaatctg ctgacattat tctattggaa aaagatctga tggttttgga acagggtatt
    16981 attgagggac gaaagacata tgccaacatg atcaagtaca ttaaaatgac tgcttcatcc
    17041 aacttcggca atatgttctc agtgcttgct gcatctgctt tgttaccttt cttaccaatg
    17101 atgagtgttc atcttatatt tctaaactta atttatgatt tatcctgtac tgcaattcct
    17161 tgggataatg tggatgagga gtttattacc aaacctcgta aatgggacgc ttccagtgtt
    17221 ggaagtttta tgatctggat tggaccaacc agttctatct ttgattttac aacctatatt
    17281 tttatgtact ttgtattttg tccattgttc gtatcgaatg gtgtattatt taatgatttg
    17341 cctgctcatt tcagcggtgc agaactggca atgcttcagg cacagtatat cgggatgttc
    17401 caagcagggt ggtttgtgga atctatgtgg agccagacat tagtcattca catgattcgt
    17461 actccaaagc tgccttttgt tcagagtcgt gcatcagctc cggtgacttt gctaacaatg
    17521 actggaatta tagttctgac cattattccg tttactgtgt ttggaactat gcttggattt
    17581 gttgcattgc ctgcagcata ctttgcttat ctgattccat gtattctgct gtatatgact
    17641 ttggcaacaa gtttaaaaaa agcctatgtc cgtcatttcg gagaactgct ttaaggaggt
    17701 ggaatgatga actggaaaga actttggatg accctttttg gaactaccga atggcttggt
    17761 cttaatatcg gcttttgggt ggctatggca gttgtgttgc tgattgttat tgtaatgaat
    17821 gtagtgtttt ggtctatgaa accaaaaaaa gacacaaaag agtcttataa ataagatatc
    17881 agtatgaatg aatcaaggga gatgcacagt ttttattgtg gaatctccct atcatatcaa
    17941 ggcgcattca attgtggcaa tttagtagta aagtatgtgt ttttttatca ttgaattacc
    18001 tataaatgct gtatataagt ggataattgt aatttcgata taaaaattat ggtacttaaa
    18061 agaaatttcg ttttttattg tttgtttacg cgtctataac gaaatcgtga aataatattc
    18121 aaaggtagat tttattatgg aatgtatgtc tgtagaagaa gcttcgataa aatgaggaga
    18181 tctctgaaag aaggatataa aaattatgta atggaaacag aatcccaaat ctattgtaac
    18241 aacaatgaca ggtaatgaat ggttacgtag attgataatt cttattcaaa ttattatcta
    18301 tctaatattg agtggtgttt tgtaattaca tttttataca aaaagaatat gttgaacgca
    18361 caatgataaa tattttgtat tccccaacta atagaataaa gtttttgctt ggaaagtatg
    18421 ttatataggc attatggttt gtaatgatca cgttgacaga ttataccgct atatatgaag
    18481 tcaaagaact taaatcattt acaagtgaga taatctatct aagtctaaaa aactggattt
    18541 ctcaatctat tatcaatgag tccattactt attatttgtg ttttgcaaag aaatgttttc
    18601 tactctagtt tactttttag ttactaaata tcgggaattg gttttgttgg actatattga
    18661 tctgaaagta tacaaaatat tatttcgtgg tctgctgtaa cccctataag tttattagat
    18721 gcacaaggat tgctacctta tatttcaatt ctactttgtt attttgcaag actgattata
    18781 aatacatacg gctttagagg ggttagttta gttctttttg aacttttgaa taagacgacg
    18841 gttgtatagc cgccgtttaa tttttgccta acgttggaca aattactgga tggtcttgtt
    18901 ttatcggctc taggggtagc cgtatgaaac acttacatat tcaacaactt tcgaccatcg
    18961 gtagttcatt aaaaaaacat ttaaattcta cggaatataa tgctcctata tgtggttttt
    19021 tacagcatat aacaggaata atttgtttag cacaagatca atacgtctgt attgcccttg
    19081 tgctttttta ctgcataaaa ctttttcaaa aaatttttgc ggttgggtat caaatcccac
    19141 ctttcacggt gagtgttagt gcgaaaagag gtagaagtct tttcgcttta gcaactttcg
    19201 ctggaaaggg ggtgagatta tgaaaccatc ttctttcgag ggcgctatca gacttcaatt
    19261 tgattgtctg gctcgcaagg ttgtaggacg aactgtaaag aactatgacc gagagcttgg
    19321 cagacgtgca agacgtgaaa cgccgttctg tgatttatct gaaatggagt taaaccagat
    19381 cggtgtcatg gacgagtatt gcgttgagtt tacgtcattt gatgtatttg gttcagaagt
    19441 ccatatctat gatgaacgct tatgtgaagc tatcaaagaa ttaacagaaa gccgacgtaa
    19501 cattctgctt atgtcctact tccttgaaat gaccgacgct gaaattgcag aggttatgga
    19561 aatggaacga ttttccgtat gcagaaatag gctgcacaca ttaaagctca tcaaggatat
    19621 gtatgaggag gaataaacac atgatgaagt ctacaaaaaa gtgtctgtca ttttcgacca
    19681 tcagctctgc ggctgatggt aacgaggtgg caatcgaaaa gattttgaac cattatgacg
    19741 cttacatatc aaaggccagc ctgcgcccgt tctatgatga acacgggaat atgtatatcg
    19801 tggttgatat ggaactgaaa ggcaggatac gggcggcatt gatgaaagca attttggggt
    19861 ttgaagtcaa agtgaagtaa atataacgag agtgtctacc acctcatttc aactctttcc
    19921 tgttctttga caagtgaata cagtaatcag atacgtttga tatacgacga gccagcggac
    19981 tggaacgcca cgaccattga aagggggata gcagagagcg ataatgccag tgaaccgcaa
    20041 gtgatctttg gaaaggttgc tgccatgact cgtatatctg gataatgata cacccgtatg
    20101 acacggttca cccatcagaa tgggaatggt gaaagtccag tggagctgcc aaagccgtct
    20161 gattacttcc ataaataaaa aagcaaggag ggttttaatg aataacttga ttaggtatag
    20221 tatgcaaatt gctatgttaa aacaactgct tgcccgtaaa ctgatttctg aaaaggaata
    20281 cactcttgta aaacaaagac tgatgaaaga ttataaagtg ctttctgaca taactgcttg
    20341 aattgtgttt ctttaagtga tataataaca ctataaaagg aacacaaaat aaggaggaat
    20401 attatgcagg aagttgaagt aataaaagca agaaatgttt tgtcaaaaca agcccgtgga
    20461 aaagccattg agcgtttgcg tgtagctgca tattgccgtg taagtacaga tagcgaagat
    20521 cagttaaaca gttataaatc acaagttcag tattatactg atatgataaa gaaaaacaag
    20581 gaatgggtgt tagctgacat ttatgctgat gaagccatta cgggtacaca agtaacaaaa
    20641 cgagaagatt ttcagcgtat gataaatgac tgtatgaatg gtgaaattga catggtaatt
    20701 acaaaatcca tttcaagatt tgccagaaat actttagaca cattgaaata tgttcgtatg
    20761 ttgaaagaga gaaatattgc cgtctatttt gaagatgaaa aaatcaatac acttacaatg
    20821 gatggagaat tattgcttgt tgtccttagt tctgttgcac agcaggaagt cgagaacatt
    20881 tcagccaatg taaaaaaagg gttgaaaatg aaaatgaagc gtggcgagct ggtaggtttt
    20941 caaggttgtc ttggatatga ttatcaccca gaggacaaga cgattactgt aaatcaagaa
    21001 gaagcggaga tcgtcagata tattttcaac cgctatgttg agggtgctgg tggttctgtt
    21061 attggacagg agcttgaaaa tctaggttat aaaacgaagt atgggagttc cacatgggca
    21121 ccatctacgg ttatcggaat tattaagaat gaaaaataca agggtgatat actcttaggt
    21181 aaaactttta ctgttgatcc gatttccaaa cgtcgccttg aaaacatggg tgaagaagat
    21241 aaattttata tgaaagatca ccatgagccg attatcagtg aagaaatttt tgaaaaggca
    21301 caggaaattc ttaatcggag aaataagaac cgtacaacgg taggcagcgg caagcgtgag
    21361 aagtatagca ggaaatacgc atttagctgt atgctggaat gcggcttctg cggcagtacg
    21421 ctatcaagac ggaattggca cagtagttca gaatacagca aggtaatctg gcagtgtgta
    21481 acagctacaa agaaaggcaa gaagttttgt ccagatagta aaggaatacc agaaacagcc
    21541 attgaagaag cgttcattga aagttaccgt ttattgtgcg ataataacaa agatgtatta
    21601 gaggaatttc ttcataggtt ggacgaaaca ttaagcaaca gtaccgtgag taaacagctt
    21661 tctaaaattg agaaagagat cagtgccgtg gagggcaaga aaaacaaact ggtggatatg
    21721 cgtcttgaag atagtataga caaggacacc tacgaaacca aatatactgc actcatggaa
    21781 aaactggaac agcttgccag tgatcgtcag aagctacagg aaacagcagt gaatgaaaaa
    21841 gacatcaaaa ggcgtctgaa agagtttaag accacacttg aacagaacga ggttttagac
    21901 gtgttcgacc gccatgtatt tgaaagtatt gttgaaaaag taattgttgg tggctatgat
    21961 gaagatggga ataaagaccc tgcacagctc acatttgttt ataaaacagg tatgaagaat
    22021 agtgttgatg gcagccgatt taagccgcaa agaaaaaatg caagaggaag acatagaact
    22081 gatgaattgt gttcacatga gagtaacgag gttaattcat tgtgttccga taatagtgcc
    22141 gacacatgtg gaaactgtag ctaagataat caaacaatag taatgtttat atagattata
    22201 tactaataat atattgtatt tgccaccgat ttgccactgt aaagtaattt tggtggcaaa
    22261 tttagtctac aatgttatca aaaatctcta aagttttatt tttaattcta tagaacttat
    22321 tataattgta attttaaaag aaatcgtcaa tctacagttg ccagatttta tacaactcat
    22381 ttttttcata gaataattta cataatctat agttgaatat tatttaatat ttttatatta
    22441 taattcacta gtaaatatag gcattacaga tgttgataaa catgtgaaag cacatatcca
    22501 cttataatta tttttttaaa aaccataaaa tcacctcttc atttgttgta tgttcttata
    22561 acaaatgaag aggtgatttc cagacaattt aaaaggtttt tgtatattga ctaaaatttg
    22621 tttttattat ttataattct taataataca tatgtaccta ctgattccat attaaactgt
    22681 ataatttttg ttcatctttt tttataatta aaactacata gttttcataa tttctcttat
    22741 atatatactt atcatctttt ttaacttcta acttatattt tttaaaatct tcttcaattt
    22801 tatttttatt acttttatta atgttaacag aatctctttt aaatttatca atatattttt
    22861 ctatttcatt aatattatct ttgcttacaa ctataccacc ttttaaatta aaaacttttt
    22921 tgaaattttt ttcagaaaat tcttgaataa aataactttg tccatctcca ttaatactat
    22981 cttgagtatc aaatacttca atttctttgt taggtattgg tatatcaaaa ttccaagatt
    23041 cctttagcat tgaaatatta gctgttttta ctaaaaaaag attatatagg atacctccta
    23101 ataacaaaac acctattaat agtaatgtga ttattacaat ttttcttttt ttcatttttc
    23161 gttcacaacc ttttgaaaaa acatgattta attcatcatt tgaaggtatg tcgtcaagaa
    23221 taattttgtt aatctaatcc ttcaaactta aaaatcattt atgtttacag aatttcattt
    23281 taagagatgt ttattttcac atagataaga gaatttaagt tctcatattt attctttgat
    23341 acaaatttac atctttatta tatttatttt aaataaaaaa taaaattatg aatactagaa
    23401 atctatctta attagctttc taacataaga ctatttaaag tagataaaac taaaaagggt
    23461 tctctagaaa accaaatcta tttaattata cttacttact aataccatca cttgatgcaa
    23521 acaagattct accacatttt ctccgtactc tagtataaaa tcatctagtt gtgtatctat
    23581 aaaatcacaa taatcatatg aactaccaat ataagcagtc agtgtacatc tatccatttt
    23641 atctctaaac atatatatta ttatccccct aaaaaacttt cataaaaaca aaaagaatat
    23701 ctctttttgg caactggctg acataactca tagtttattt tataagcgtt agtccctata
    23761 gctttgcgtc actaaatttc tctagttttg ccgatttagt tttattctac aattacaata
    23821 atacaataga attggttatt attcaatata cttatttgaa aattaaatga atttataaat
    23881 atgaacgtta ttttatatca aaaaaatagg ctatgtatgt agaatgtatg gaaaaacttg
    23941 attgtaggtt ttgtattaaa agacctttgc tattaattta agttagataa attgagcgat
    24001 aagcataaaa tgagaaaaca aataatagca gttaattttt attattaata ctaggtaaat
    24061 attaaatttt aaaataccac tagattttat agaataagaa aatgagacaa acataaatat
    24121 atgaatatat taaattatac ttgaacatac ttatatttta tggtaaaatt tcaataataa
    24181 ttattagtaa aggagtgttt tgcctgatgt cagagttata tataatggta accaacaaat
    24241 aaatagttgg agacgcatat gggttctgtt taatcagaat ttttaagtgt atttttgata
    24301 catttgattg ttgtgtctta ctctgccttt atagataact aacattagac aacaaataat
    24361 aatattacat attactttgt taaattgtgg tgtagtgggc tttaatctgc tacactttta
    24421 ttaattttac acagtattat tttgaatata attatgttga aatagaagat attaaatttt
    24481 ctagtccaca ggagttttct gtttttgtgt aggtaaatat gtataccaca taaaaaggca
    24541 gatataaata cctgtggact ttttttgtag aaaatacaag atacggagga aataaaaatg
    24601 aattataaaa atagaaaacg agcttattat caggaaaatt cctgtatgga taactttatt
    24661 tgcaaaaatt gtggttaact tgtagttcct gaaggagctg gtacacaaca tagaaatcat
    24721 tgtccacatt gtttacatag tcttcatgta gatatcattc ctggtgaccg tgctgcagat
    24781 tgtgatgcta atatggaacc tattggagtg tgggtgagaa aaaatggtga gtgggcaatt
    24841 attcatcgtt gtacacgctg tggacatctt agttctaatc gtattgcagc tgatgataat
    24901 tcagtgaaat taatgtcaat tgcattaaaa ccactgtcac agcccccttt cccactagaa
    24961 agaatcattg aaaagttgga aaaggaggaa acagaatgaa tggtatgaaa caaatcaatt
    25021 tacaagacta tggactaaat aggaatttta ttactcaaag tatggaatat catgatttat
    25081 accttgctcg aattatctcg caggaaaaga atttttatca agctgtatgt gtaaatggtg
    25141 tactgtttgc agaagtttca ggaaaactac gttttgaggc tactatacaa tctgattttc
    25201 ccacagttgg tgatttcgtt atgttggatc gttgcaataa taaaaatggt aatgctatta
    25261 ttcatcatgt gcttcataga aaaagcttgt ttgtgcgtaa ggctgctgga aaggtaaatg
    25321 aggaacaggt ggttgcagct aatattgaca ttgttttttt gtgcatgtca ctgaataagg
    25381 attttaacat tcatagattg gagaggtatc tgtctttaac atgggaaagt ggagctatcc
    25441 cagtagtagt acttactaaa tcagacttat gtgacaatgt gcatcgtaaa ttacaagtag
    25501 ttaattctat agccttgggt gtagatgtag ttgttacctc atctatagag ccagatggtt
    25561 ataaacaggt ttctaagtat attaaaccag gctgtactgt tgccttactt ggttcttcag
    25621 gagttggaaa atcttcatta attaattgtc tgctgggtgg agaattttta aatacaaagg
    25681 aaattcgcat agatgatgat aaaggaagac atgccacgac tagacgagag ctatttttaa
    25741 tttcaggtgg tggtattgtt attgacacac caggtatgag agagttggga atgtgggatg
    25801 tttcagaagg tttagataaa agttttgcag atatagaagc ttatttcgga aaatgtcatt
    25861 ttcgtaattg tactcacacc tcagaaccag gatgtgctat ttgggaagct attgctcatc
    25921 aagaactttc gcctaaaaga tgggaatcct atcgtaggct taaaactgaa gcagtatttg
    25981 cagacaataa aatcgaatac ttagcaaaaa aagaaaagaa atttaaaaat atctcaaaaa
    26041 taaataagaa gattagaaga taagtgtagt ttttttgttc attatatgag tctacatact
    26101 attaatatat taaatttgcc atcaatttgt tactttaatg tgattttgat ggcaaatttg
    26161 gtttgtggta ttatttaaag caatttatta atttttttaa taaagtttga ttttttatat
    26221 gatgatatat acatgtgata atgtatacat atttgttacg atgggctctt ttataaagag
    26281 gtcttatgta agataagaaa aggcatattt atactaatac ataatagagt atatgcttat
    26341 gtatgataga ggtgtttctt aaaagcaaaa ctgtaatatt actaatttat aaagtaaaaa
    26401 tacatgaatt ataaaatata aataagatat ttataaaaat tattgtttta atttataata
    26461 aaaatttttt gttgaaaata atgctcgaat ctataaaact attaactaat atttgtaaat
    26521 gtatactttt gatgatagaa tataattaag ttaagcttgt tttttataaa acataaattt
    26581 attttagaga ggtgaaataa atgaaaatat ctagtcaata tagaagtcaa tattcattta
    26641 gacatgaaag taatataaat aatacaagaa taaatgaaag tatagttaag aaaaatgaaa
    26701 ctgcaggaaa agacacttat ttatctaata ttatgaaaca aaagcaagaa cttaatgata
    26761 gaattagaga tttaaaagat agacaagaga tttatactaa aaaaataaat gaagcaatta
    26821 agaacttata taaatcagaa ataagagaaa caactaataa cttttctaat atagaaatag
    26881 gtattaaaaa tagaattata gaagataaaa ataaaagtac aatgttagat gaaaattcaa
    26941 cttatctaaa tacaaatgat gaaaaagaat ctttaatcgc taaagaattt aatgaaaaag
    27001 ttgaagaaga aatattaaat gatgaaaaat tagaagagtt agaacaaaaa aaggattata
    27061 aagaggattc taataaaaaa gagacagtat ctgaggactt atccttagta ggtaaaactc
    27121 gtgaagagct tgaaaatatg cttaaaaatt ttataaattt aacacaagaa gaaataatga
    27181 aacttgagtc gagaatagaa aagttagata aagatgctga agaatacaaa caaaattcaa
    27241 agactaatat atttgataaa acagatgaac aaaaaagacg tataaataca ttagtttaaa
    27301 tagtctgttt taagaaaata aatttatgat taatgaaaat gtaaagatac aatttcaata
    27361 catttctgct aaatcaacaa tttgtgaatc tgacttaatt ttaattatac taatagccat
    27421 atatttataa gttgataatt ttatgtttta aaaagcatta aataaggggg agtaatatga
    27481 agaagaatat attaactact gtgattacca tgattattat atttatgatg agtatgacag
    27541 taatggcaga gcaatatcaa gcagatgaaa catctagctt gaaaaaacag agtgaaaatg
    27601 aaagtaatca aactagtgta ggtacaatgg atggcagagt gcaaacaaat gcaataagta
    27661 aaggtgctaa ttatgacccg aagtatcctc ttaaaggaat gttaacacaa cttggtctta
    27721 atacaacagg taaagagggg tgggatttac tctatggagg aaatccaaat ggagttgagc
    27781 ttcgagcaga tggtaaatat tattatataa ataagggtat ggaagggcta ggattttatg
    27841 cggcagcatt agcgggtggc tcatatcaga gaataggctt tggaaaactt gaccctatag
    27901 aagtaatagc cgatggagat tggatttctt acaaacaagc tcaagataca cttacagtaa
    27961 tcaggaattt tttaaatagt tttgactgga gaaatgcatc tgagatggaa agagctaata
    28021 gagctgcaaa attggtaacc gaagcaaaat atgcagacgc caaatattgt aacatagtct
    28081 atggtaatct ggttgataaa cgtggtgtat gtggaagttt tgcaagtagc tttcatttat
    28141 taacaaggtt aatgggaatg gattcactat ctatattaaa tccatcatta aatcatgctt
    28201 ggaactatat acaaattgat gggaaatggt ataggtttga tgggtctgaa atatcagctt
    28261 ttggtggatc attagacttt gattaccgta aattaaagta tgcaacgaga gagatgacta
    28321 cttactatga tgttaaggca ttgtctatat taggatttaa tcaataaaaa tagggaaggc
    28381 ttcttatgga gccttttttt attgatttga aatttaataa ggaattttat attaaaattt
    28441 aatcaataaa agcaaaaaag gctctttata aagcctcttt aagtgttttt ttcaagtaaa
    28501 attttttata tcaacatcag ttttaatcaa aaaatataac attttggact tacttttaaa
    28561 aataaaatta ttaaaatata atattaatca tgttaataat gtttttagtt tattatataa
    28621 tagtggttat gttgactatt gtagttttat taaaaatagt tggtttatat aaatatatgc
    28681 aaagatagct tgtggtttac tttatttatt agtatatagt aaaagatact ctgataaatt
    28741 tgcttatttt aatatctttt gcactaaaac caactaaagt ttcctttatt atttcgtttt
    28801 gaataataca aagcataatc cgattgtttg tataaagact ggaaagtatc agagttattt
    28861 tctaatttag atatacctat agaacaagaa ttactctcta ggcataattc taaaactttc
    28921 tttgctttat tttcaacatt ctcttttgat tgattactat attcaaaaac agcaaattca
    28981 tctccaccaa gtcttccaat aatagcatca tttacgaaga ctttagtcaa aatctttgaa
    29041 aaatgtatta gtatttcatc tcctcgaaca tgaccaaaga tatcatttac ctgtttaaaa
    29101 ttatctaaat caaagatgta aaagtatcca tgtgaaacag ttttaagcat ttcttttatg
    29161 tgtacttcaa aaaaatgtct attgtatagt ccagtcataa ggtctttttc tgattttagt
    29221 ttaaattcat ttgccattgc tagtgcttct tgtgcttttt cagttattgt tttagggtaa
    29281 tactcatctt tcatttggtc aaagtttgga atagaatggt gaacatggat aagtttaatc
    29341 atatcatctg taattctgta taccatagta aatcgagtat ccatttctac atagatatct
    29401 ttttctaggt aatctttttc tattacccaa agagtaccat atactataaa agcttcgtct
    29461 gtaactttgg tacatgaata ccactcatct ataatctcaa agtctatttg ctctgattct
    29521 gtttggtctt tttcaagacc tataataaat tcttctaatg tttcgtaaaa ttcatgtttt
    29581 cctgttccaa ttaatgcaag gttgtcatct aatatggaaa taataaattt aaggttttct
    29641 tcttctggat ttaaaatata aatatgccaa attttttttg ataaatccct taattgtttt
    29701 tgtattgtat tattttccat agattacccc cttaagattt acagtttata ttttaatgta
    29761 ttataagttg aactcttatt acaatattat tataatatag aactaaagaa attacatcct
    29821 gtataggtaa aagtatatct tttacaataa aaatattaca gtaaaataac ccgttttaat
    29881 atacgtatta tatttttaat ttataaatga atattataaa tgaaatttaa attcaaccct
    29941 gaagaaataa gctaaatgta ttagtatata aatccatact tgaacataaa taacctttat
    30001 gatatgatat caataataat attatgagag gagtgccttg atgtcggagt tatataatgg
    30061 taaccaacaa ttaaatagtt ggagacacat atattctgta taatcagaaa ttttaagtgt
    30121 atttttaata catttaattt ttgtgtctta ttctgccttt atagataact gacatatgac
    30181 aacaaatagt atttaaaata tatattactt tgttaaatta tggtgtagta ggctttaatc
    30241 tgctacactt ttattaattt tgtatagtat tattttgata actattttga aatagagagc
    30301 attaattttt ctagtccaca ggagttttct gtttttgtgc tgttaaatat aagcacagaa
    30361 aaaggcagat atatacctgt ggactttttt ttataaatta tgaaatatgg aggtagttaa
    30421 aatgagcata attgaactta atgaactgac taaatcttat agaagatttg agaaaaaggc
    30481 aggatttatg gggagtgtaa agtctctact taataggaaa tatacagaaa aaacagctat
    30541 atcgtcattt gatttaaaga tagaagaagg agaatttgtt ggattaatag gtcaaaatgg
    30601 agctggcaaa actactctta ttaagatgtt aactggtatt attgcaccgt cttctggaga
    30661 aatatctgtt atgggttatt accctaacaa attagaaaat aattttaaaa aacaatatgc
    30721 tgttgttatg ggccaaaaaa gtcaactatt ctttgaattg acaccagcag atacgtttct
    30781 tttatttaaa gaattatatg atatatctaa tgaagaatat aaaaaaaact tggattactt
    30841 tatcgaatta tttgaggtat ctgactattt aaatgttcaa gttaggacgc tttctttagg
    30901 agaaagaatg aaaatggaac taatagtagc ccttctacat aatccaaaaa tattattttt
    30961 ggatgaacca actataggct tagatgccat agcccaaaaa caaattaggt atttcctaaa
    31021 agaagtaaat gaaacaaaag gaactactat tatacttact tctcattaca tggaagatat
    31081 taagagtctc tgtagtagaa gtattgttgt agaaaatagc cataaaatat atgatggttc
    31141 tacagagaaa ctatttaatc attttcaaaa atataaaaaa ataacagtta gtttttccaa
    31201 tgaaactaac attgtatttc caaaagattg taaagttgtt gaacaaacaa atcataagac
    31261 atcagtaatt gtgccaaaag aaagaggcaa tgaaacgatt aaatggattt ttgataaata
    31321 tgatgttaaa gatgtaatga ttgaagaaga agatataggt agtattgtgg agagaatata
    31381 taagaaagga agtgatgagt attatgagca actataatga agcaagttca aattcttcaa
    31441 tgttttataa atttaaacag agtattagaa ggtattatga agtagccaaa attaacttta
    31501 aagtgcaact tatctggaga tttgatgtgg tggttaatat ggtgtttacg attgtaaaaa
    31561 ttttatttgc ttatatttta tggaaagcaa tttttggtga aaataaaata gtctctggtt
    31621 ttacatttaa ctctatgttg tcttactata taataagctc atttttagca ggtattgata
    31681 tgtcaaagag taccagtgaa gagatatgta atcgtgtaaa attgggcaca ttttcaaagt
    31741 acatgattat tccaattaat gttcaaaatt attttattgc taaaaatttt ggaatgacgt
    31801 gtttttattt tgtatttaat atgatttctg catttgtatg gatttttata tttaaaatag
    31861 attttgcctt tacatcaaat ccagttcaaa tattaatttc aattttgatg atttttctag
    31921 ggtttatttt tatgatgaaa ctccacttct ttattggaat tttgtcattt aaatttcttg
    31981 agattagttt ttttagaatg ataattgaaa atattgttga atttattaca ggaacaatga
    32041 taccacttgt actcttacca gaaactatag taacagttat gaagatattt ccattttatt
    32101 atacaacata tttgccatct atgttactaa taggtagaaa cagcaatgag gcaatacaag
    32161 gattaattat tctagcatta tgggttttat ttttttctgt agtaaataaa gttatgtata
    32221 aaagaatgag aacattattt gatggggtgg gtatatgatt aaaaaaaatt tgaaaataat
    32281 atttatgtta ttaaaaatga aattatcaaa gatgatggta tttagatttg atttttttgg
    32341 agcatttttt gtagatagtt cattatttat attacaactt ctaatgttta atagtatata
    32401 ttctcatgta gactcaatag ggggatggca acaaggagag atgttaatat ttataggaac
    32461 tttctcatta ataaatgcga taaatatgac gattttcttt tttggtattt atgatattcc
    32521 acgaaaaatc caggaaggag aattagacta ctatattaca aaaccattag acccactatt
    32581 taggttaaca tttgaaaata ttaatattgg ttcatcacca ttaattctag caagtatact
    32641 tattgtttta tatggaatat ctgagttaaa ctcagagata actttagtta tgataataat
    32701 atatattttc atggtgttat tgatgacatt acttttttat gatgtatgta tcatacttag
    32761 aacagtttca ttttttgtta tatcatcttc tgcgataatg agattagaag ataatttatt
    32821 gccaatgaac atgaaaattc ctggtgtaat atatgaaggt gtttttaaag tattattcta
    32881 tctaatctta ccatatggaa ttatgtcgac aattccgact caaattttgg ctgggacaat
    32941 aacaattaat ggattaatat actcaatttt aattgtattt ttgtttacat tgtttatgtg
    33001 gagattttgg aagttaggta tgagacatta taaaagtgca agtagttaat aaattggtaa
    33061 aaatagaaaa tgtataatta tatataaata cgtttcatat aacactaaac tatgtaaaca
    33121 agtatttgca ctaaaggcac tgaaagctat aaaattatta aagtaaggat ttaaaagtta
    33181 ctttagtaga aatataattg tgtaaaaaag caagattaat taaaactata tccgaataat
    33241 tagatataat ttttatgcag aaaggaggtc tgtaaatgtc taattgtttg gaatatattt
    33301 taaaaataat taatgtacag aaaaataaac aaaatgagtg atgtatatta ttcagaaaat
    33361 catgaacaag ataatcttta tgagcaagat aatttactgg cacaaagatt taatttattt
    33421 actctattga agtttgcatt tcctactatt tttatgatga tttttatggg gttgtataca
    33481 atcgtcgata ctatatttgt atcaagattt attaatacaa atgctctatc agcaattaat
    33541 attgtatgtc caattattaa tcttatagtt ggaattggaa ctatgcttgc cactggagga
    33601 agtgctattg tagcacgtaa gatgggaaat ggtgatattg agggagcaaa taaagctttc
    33661 tctttaatcg tattatcagg agttgtaatt ggggtaataa ttactggtat aggtattgta
    33721 tttatggatt atatcattat atggttagga gcaagtgaag ttttaattaa atattgtcgt
    33781 tcatatcttt ttattatctt gatttttgct tctgcgaata tactacaagt attatttcaa
    33841 tgtttatttg taacagctgg aaagcctcaa tttggattat ggctagtgtt aggtgctggg
    33901 tgtgctaata taattcttga ctatgtgttc attgttctgt tacaaatggg tattagtgga
    33961 gcagcacttg caactggagt aggataccta attcctacca tttcaggtat ggttttcttt
    34021 tcaaaaaata aagggttact taaattttgt atacccagac tagataaaag aatattattt
    34081 gaagcttgtt ttaatggttc atctgaaatg gtgggtcaac tatcaacagc agttactact
    34141 tttttattta atgctatgat gatgaaatta attggtgaag atggagttgc agctattaca
    34201 ataattattt attctcaatt tcttttaact tcgctttata taggtttctc aatgggtgtt
    34261 gcaccaataa taagttataa ctatggaagt gaaaataata cgcagttaaa tcatgttttt
    34321 aagatttgta tattatttat ttcagtagca tctttattgg tatttatctt ttctatatca
    34381 tgttcaccaa tcattgtaga gattttttct caaagaggaa gccgagttta tgaaattgca
    34441 aggtctggat tttacatatt ttcttttagt tttatttttt gtgggtataa tatttttact
    34501 tcgtctatgt ttacagcatt atcaaatgga aaggtgtctg caatattatc ttttctacgt
    34561 acatttggat ttataactat aggtttattg atattgccaa atatattaaa tataaatggg
    34621 atatggttag cagtaccaag tgctgagatt ttaactttat ttttaaccgt tttttgtata
    34681 tgtaagtata agaatagata taaatatatg tagatattaa ataaatagtt taggtagata
    34741 ttttatgttt taataagtaa ttcaattagt ggtagataga tactattgaa aattaaagtt
    34801 ataattgata taaagaatta ataaaaataa catataaaag tttaaaaggg gagttgaact
    34861 taaagtttga ttagaaaaag tcaattttaa gacaactcct tttattttac tattgtatta
    34921 atttgtatct gtaagtgtat tagtctaata ttataaactt tggatgaaat taattttcta
    34981 taggttttaa tgtatcatac actttatttt aaagaaactt atcttaattt tcatagtgat
    35041 tgaatttgtc tgttagagat gttactatta gtaatgtaaa agcaagagta gtgaatataa
    35101 aaaaacaaga tagtgatact gcaagattag aatataataa atttttatgg agagatttca
    35161 atatggatac atattttaat aaaaaaatat tacttgttga tgatgaaaaa gatatagtag
    35221 atttaattga agaagtactt acaaatgatg gttttaaaaa cattattaaa gcttataatg
    35281 gtttagatgc tatttcgctg tgtaagatag catgtccaga cgttgtcatt cttgatataa
    35341 tgttaccaga tatagatggt atagaagtgt gtaaaaaaat tcgagagttt tcatactgtt
    35401 ctattctttt tctctcatca aaaaatgatg atattgacaa aatactaggt cttagtagtg
    35461 ggggagatga ctatataaca aagccattca gtccaagaga aattgttttt cgagttaaag
    35521 cgcaattacg tagacaacag tatcaaagta ttgtaccatc agatagtgaa gttattaagg
    35581 taggagatat tactattgat atagaaggaa accgtgtata taaagataga aatgagattg
    35641 agttaactgg aagggagtat catcttttaa gctacatgga tcaaaatgta aataaaatta
    35701 taggaaaaga aagactctat gaacaagtat ggggagtata tagtagtatt tgtgacaata
    35761 caattatggt gcatatacga catataagag aaaaaattga agataacccc tcaaatccta
    35821 aaatacttat aacggttaaa ggactaggat ataaacttgt gaatagaatc gattagaata
    35881 gattttaata tcaattaaga tgtctcaaat tgaatttttt agttaatgag gcattctttt
    35941 atgtgtgaaa tcaaatgtat tttcgttatc tcaataatga agaagaggtc tatctctatt
    36001 ttgagatagc ctcattaagt ttatatcctg gcaatgtact ttatgttcta ataaatattt
    36061 attttttagt ttatttgcag tgaaacatta actagaacat taaaatttgc attgaaatac
    36121 caattaaata atattgtata ttgtgtataa acttatacta attgtttttc tatattaaat
    36181 actttatcaa tccaaccttt ataaaatttt tcttcatggg aaactaggat tatacttcct
    36241 ctaaactgtt tcaaagcatt ttgtaaagca tcctttgtct ctgcatcaaa gtgattggtt
    36301 ggttcatcca gaataagaaa attacaagga gataacatca tacaacataa tttaacctta
    36361 gattgttcac caccacttaa agtagataca cttcttgaaa catgctcttc cttcacacca
    36421 catctggcta gatgacgtct aatctctttt gtatttaatt ttggatattt atctgctact
    36481 atttgaagtg gggttttatc aggattttcc cattttaaat cttgctcata ataaccaatt
    36541 ttaacttgtt ctgaaaactg gaaatctcca gatatacgag gaatatcttt gactaatgtc
    36601 tttaataagg tagatttacc gattccatta aaaccagtta taactatttt ttgacctcca
    36661 tcaacagaaa aatttaattt tggaagtaaa gaatagtagt atccaacttc aagatttgtt
    36721 atagtaagag cattttgagc cgatatctca atttctgaaa attgaatatt tggttttcct
    36781 gtaaaactag gaggagctat tctttctatt ttatccaatt gtttttgtct tcctcttgca
    36841 atttttgaat ttactccagc tttattttta cgtataaatg tctcttcttt ttctattttc
    36901 ttttgttgtg cttgatacct tctaatataa tcttctctta aatgtgattt ttgtttaagg
    36961 aactctgaat attttccatg atatttctta atcatgccaa attctatatc aagaatacct
    37021 gtagaaattt tttctaaaaa gtcaaaatcg tgggaaacta caataaatgc cccattaaat
    37081 gtatttaaat aatctgagag ccattcaaca tgttctttat ctaaaaagtt tgttggttcg
    37141 tctaataata gaacatcatg gttagaaagt agtaattttg ctaaaattac ctttgccctt
    37201 tgcccaccac taagctctcc aacaacacga ttcattccta ttgaatctaa tccaagacca
    37261 tttgctattt tatttatttc attatctata gaatagaaat tatttgctat tagttgttcc
    37321 tgataatctg atgctttgat tagatattgc tcatttccag atatagcact tttttgatag
    37381 agtaaattca tttccttttc tattttataa agtttttcaa atgcagtgtg taaatagagt
    37441 gatattgttg tatctttatt gatttctgca tattggtcta aatgtcctat attgatatta
    37501 ggttgccact tgatttctcc tgaatctgga acaacttctc ccaataaaat tttaattaat
    37561 gtacttttgc ctgcaccatt ttgaccaact acacctatat gttcaccttt gaataaatca
    37621 aagttagctt tctcatacag tgatttatcc ataaaacatt gtgataaatt agttactttt
    37681 aataaactca taattcaaac tccttttctt ttattaaaaa atttatggaa ataaaaaaag
    37741 cagaggaatg gcattgtaaa atgccgacct ctgcttttgg aaaaacaaaa ggtcatagac
    37801 aagcattgtt gtctatgacc agaaaatcta tattatctat cggcaaatag gtaattttaa
    37861 ataagcatag ccaaaaaact atactaaacc tatatttgcc gatgaagata gaaagcttta
    37921 agctttcaga ttaacctcta cacaacgctt catcgtatac atttgtgtag agttaagttt
    37981 tctaacaagt ttaactaatt ctatataaat cataattatt cacatcctaa tcttagtatt
    38041 aattctagtt tatctatatt taaattgtac ttttgtactt tgtggattat cttatttatt
    38101 taaaatatgt tttattaatt atagcttaag ttatgttatc ataatactta gttatagtca
    38161 ataagaaagt tatatttact atatattata ttaatttagc aaatctatca ttacaaagtt
    38221 atttgaagat tcgctaccaa taaagtttta tagtctgtaa gaaaactaag attatgagtt
    38281 ttataatttt gatataggga tactattttc ataaatatta taatatgtag aagtatatgt
    38341 ctagtattgt tgaattttca atgatatatt aaggttctaa tatattatac aaaataaaaa
    38401 cattaattca acttaagtaa ttttaagtat catatgtgtt ttgattaaat agacctaaaa
    38461 ttttaagggt aaataacata ttcacattaa attttattga aatgattaaa attatttact
    38521 taatgtaaat tattagctaa aattgtacta aataattaag gaggtgagta gctttggatg
    38581 agatagattt aaaaataatt aattctctaa aaaagaatag tagggcttca acctctgaaa
    38641 taagtagaca aattaattta tcagtaccag cagtctcaga gcgtataagg aaaattgagc
    38701 agtcaaattt aattcaaaag tacactattc aaattaatcg agaaaaaaca aaatataagc
    38761 ttttggcttt tatatttatc aatactgatt tatctaaaag tatgaaagaa tttaagaaaa
    38821 ctatattgga atatgatact gtattagaat gtcatcatat ttcaggagag tatgattact
    38881 taataaaagt attagcagaa gatacaagta atcttgaaga gtttatatca gtgactttaa
    38941 aggaaattgg tgggattcag aaagctaata caaccattgt tttatctaca attaaagaag
    39001 aatttaatac aataaaagat attttttaaa taattgacta gtaaagtgtt aattatattt
    39061 taggaggaaa atagaatatg aaaattttag tttttttagc aaaaggtttt gaaactatgg
    39121 aatttagtgt atttgtagat gttatgggat gggctcgtaa cgattatggg catgatattg
    39181 atgtagtgac ttgtggattt aaaaaacaag ttatgagcac atttaatata caagtattag
    39241 ttgataagac gatagaagaa gtatgtgttg atgactatga tgctctagct attcctggag
    39301 gatttgaaga atttggattt tatgatgaag catatgattc atctttttta aatctaataa
    39361 gggagtttaa ttcaaaagaa aaaataatcg cttctatttg tgtggcagca ttgccagttg
    39421 gaaaaagtgg tgttttaaaa aatcgtaaag ctactacata tcatttgaaa aatggtaaaa
    39481 gacaaagaca gttaagtgag tttgatgtaa atgtagttaa tgaaccaatt gttgtagata
    39541 aaaatattat aacctcatat tgtccagaaa cagctccaca tgtagctttt aagcttttag
    39601 aaatgttgac atctaaagaa caaatggatg aagttaaatt agcaatggga tttaaactgt
    39661 aatggtttat agattttcta agtaatcaga accccagtca cacatggaat ctaaaattgg
    39721 aataatactc tttccaaaat cagatagcga gtattctact ttcggaggaa caacaggata
    39781 aaccactctt ataattaaac catctgattc taattcacgt aattgttgcg ttaacatctt
    39841 aggcgttgct ttaggaatta atttttttaa ttcattgaac ctcaatatag tgtctttaag
    39901 atgccaaagt ataagtgtct tatatttacc accaatcaat gcaagtgttg cttctattgg
    39961 gcaactgtaa ttatctaaac attttttcat ttttgggctc ctttatttat tttaaagtat
    40021 ctttttaggt actatattac aaaaaagtgc attattgtaa tatagtacca tagtgataaa
    40081 attatagcat aggttaaata aatcatcaac ttagcctaat aaaacaatag gaggtaaata
    40141 aatgaatttc gttgaacttg caaaaaaaag atattcttgc cgtaattatc aagatagaaa
    40201 ggttgaaaaa gaaaaacttg agaaggtttt agatgttgca agaatagctc caactggtgg
    40261 taatcgtcaa cctcaaagat tgattgttat tcaggaaaaa gaaggtataa ataaactttc
    40321 taaggctgcc aatatatatg atgcgccatt agcaattctt gtatgtggag ataaagacaa
    40381 agtttggaca agaccttttg atgggaaaca acttacagat attgacacaa gtatagttac
    40441 agaccatatg atgttacaag caactgaact tggattggca agtgtttggg tgtgctattt
    40501 taatccagat ataattagag aagagtttag tttgccagat aatctagaac caataaatat
    40561 attattgatg ggatatgagg ctggaacacc agaaagtcca gatagacata ataaaactcg
    40621 tctgccttta aatgaaattg tttcttatga aactctttag atataaaagc aagttatcta
    40681 tatgaggtat ataatgagtt ttttcaaaat aaagtcttag aaaaagttaa tacttatata
    40741 aaattaattt tagtgaagta tatatctaat tgaataatga tgtatacttc actattttaa
    40801 ttgctctaaa tatccaacaa tattttgaat atctaataaa cttaaacttt cattctatta
    40861 gctaaaatac ataacttaaa ttaattttta agtctggaga atcacttaaa atataacttt
    40921 tttactttac ttggtgtttt tgacaaaatc tagattctct tttattttat gatataatct
    40981 taacaagtta aaagtggtaa agtttttaca acaatttatt tttaagtatg tattttactt
    41041 tagttttttt acaactcaca tatccattta cacaacatgt ttccaattgt attgtgtaga
    41101 caaattactt attgtattct taaatcatca attaaggaag gtagatgaaa tggatgaata
    41161 agataataga agtaattaat ttacaaaaaa gctatgatac ttttaaagct gtgaaaagga
    41221 ttaattttta tgtagaggaa ggtaatttat ttgcattact gggagctaac ggtgctggaa
    41281 aatctacaac aattgatatt ctttgtacat tgttggatta tgatagtgga gaagtgatta
    41341 tagatgggca taagttaagt gttgaggata ataaaattaa agaaaaaatt ggagtagtat
    41401 ttcaagaaag tatattagac ccacttttaa cagtaagaga gaatcttaca tttcgtgcga
    41461 agttttatat taagaataaa ggtaaagtag aacaaattgt acatgaatct gctttatctg
    41521 taggggctat ggaatttata gacagaccat atggtaaatt gtctggaggt gaaaagcgta
    41581 gggttgatat agcaagagct cttttaaaca ctcctaaaat actgttttta gatgagccta
    41641 caacaggact tgacccagaa gctagaaaat gtgtatggga tactatttta aaattacaaa
    41701 agcaatatgg tttttctata gttcttacta cccattatat ggaggaggct tcaaaagctg
    41761 attacattgt aatgcttgac tatggcacta taacagcaaa aggttcacct catgaactaa
    41821 agcataaata cagagcaaat aatttagatg atgtattttt gaatatagtt agaaatagag
    41881 gtgaaaaaaa tgtttaatct agcacaaaga aatataatga tttttttaag aaataaaaga
    41941 ggagtatttt catcttttct aggtgcaata attgtaattg gcatatatgt tattttttta
    42001 ggtgaaaatt taaaggaagg atatccaaat attaaagaca tagatatatt aatgaacagt
    42061 tgggcaatgg caggaattat ttctgttgtt tctgtaacca caacaatggg ctcatttggg
    42121 attacagtat tggataagga attaaaaaga actaaagatt tttattgttc accaattaag
    42181 acaagagaac tggtaggagg atatatttta agttcatatt taattggtat aattatgagt
    42241 atatttacat ttgtgcttgc agagatatat attgtattaa gtgggggaca aattttatca
    42301 atgttttcta ttataaaagt tattggtgta atattattaa cagttttatc atctagtgca
    42361 atgttatttt ttattataaa tttgttgaat agtatagata cttttgcaac tgcttctacg
    42421 attataggta ctcttattgg attcttgaca ggaatttata taccaattgg aagcttgcct
    42481 caagcagtac aaaccattat aaaggtattt ccaatttcac atggtactgt attacttaga
    42541 caaattatta cagattctcc atcaaaagta gtctttgtag attcaacaaa tgcattaact
    42601 gcctttaatg aacatatggg agtaacattt ggtagtattg gtagtttgtc agaaacttca
    42661 attcatatta tgtttttagt tatttcatca ataatatttt actttgttac tataattatg
    42721 gtatcgaaaa agaaaactaa aaattaatag tgcaaaaata taatagagtc tttttataga
    42781 aatcaaaaga agggatgtgt tagagtgaaa ataataattg aaactccacc agatggagca
    42841 gaggatgaaa ttatcataag atgcagaaat cttgatgatg aaatgattaa gttgattttt
    42901 aacattaaga tgcaaagaga gtctttgata gcatataaaa atgaacaact ctatcgtatc
    42961 aatcctttag atatttatta ctttgaatct atagataatc atacttatct ttattgtaaa
    43021 aatgatgttt atgaatttaa gaagaagctt taccagattg aagaaatttt ttcaaatggt
    43081 gattttctta gaatatcaaa gtcggtaata ttaaatctta caaagataga ttcgattgta
    43141 ccagcattta atggtagatt tgaagcaata ttagataatg gtgaaaagac aattatttca
    43201 cgccaatatg taccaatgtt gaagaaaaaa ctaaggatat agaggagttg attaaatatg
    43261 aatttaataa atacactaaa aaatgtagtt cgttattttt gtatgataac tacaggagtt
    43321 ttaatatctg tttttacttc ttgcctagta tttagccctg aggagacgtt taatataagt
    43381 attttccaac agatattatt agttgcattg gttacatctc tatccacatt aattttttat
    43441 tcaaaacgag aacttggtag aaaagagatg ataattcgtc aggtaattca tataattttt
    43501 atatttgttt ttgttctgtg gttttcattt aaaagtaaat gggttgatgg tggtcatatt
    43561 tttcaagcat tatttatagc actatctata tttattatct atatttgtat aacacttgct
    43621 acttgtaaaa gagataaaaa agaatctatt ttattaaata aaggtctaaa agaatatagg
    43681 aaaaataaaa tcaataaata ataattaaag caattcaaga aattgtaaat ttattattaa
    43741 ttaagtttta tatcagtcaa taatttaaga tagcaattta tattaagaag aaaattcttg
    43801 cataggttat aatacttaaa aggagaggat agagttgaaa acaaatacag atgttattat
    43861 ggagataatt gattatatag aagaaaatct tacagaaaat ctaaatttag ataaaatagc
    43921 tgatattgct aattattcaa aataccattt acacagaatg tttacaaatg ttgtaggatg
    43981 tactatccat caatacatac agaggaggag acttactgaa gcagctagac aacttatatt
    44041 tacagacaaa tatattatag acatagctat tacagtagga tattctacac atcaatcttt
    44101 tacactagca tttagaaatt tatataaaga atctccacaa gtatatagaa ataaagatga
    44161 attttatcct attcaacaga aatttgtttt aaatctaaat catcaaattc aaagcgaaaa
    44221 atgtatttcc tatgcaaata tgaattataa acaaagaaga gatgaaatca attcttatct
    44281 taactttaat attaattgtg aggtgaaagt agcatgagtt tagtgccaca tgtaattgaa
    44341 caaacaggtc aaggggaaag gtcttatgat atatattcaa aattattaaa agatagaatt
    44401 atatttatag gagaagaaat taatgatgct attgcaagtt tagtagtagc tcaattactg
    44461 tttttagaat cagaagaccc agattcagat ataattatat atataaatag ccctggtggc
    44521 tctgctacat caggatttgc tatatatgat actatgaatt atgtcagatg tgatgtatcg
    44581 actatttgta ttggtatggc tgcaagcatg agtgcttttt tacttgcagg aggaacacat
    44641 ggaaaaagat gtgctttacc taattcagag attatgattc atcagccaat gggaggagct
    44701 aaaggtcaag caacagatgt aaaaatagct gtagataata tattgaaaat aaaagaacga
    44761 ttagataaaa ttctttctga aaatacaggt aaatcaatag aagatattag gagagataca
    44821 gatagagata attttatgac tgcactagag gctaaagagt acgggctgat tgattatata
    44881 atgaatagga atgaataaag tatcaaagta tcatattaaa atgtctgttt tacaaatata
    44941 tatataatat taaataagag tgtctcaaaa tgaacttttt agtttatggg acactctttt
    45001 ttgtatgaaa ttaaatatgg ttttatcatt tcaacaatta ttaccaaatt tcaagtttaa
    45061 taaattctac tataaaaaat acataaaaga taaggttctt tagtaacttt ctgtcgtcaa
    45121 aagtttttat aaatttaata acaaaacaag agaaaatacc atatattact tatgtctgca
    45181 atatatagaa gacaaaggag ttgtacatta tgattacaat aagtttgtgc atgattgtta
    45241 agaatgagga agaagttata ggcagatgct tagaatgtgt aaaggatata gtagacgaaa
    45301 ttataattgt agataccggt tctacagatt tcacaaaaga aatagtctca aaatatacag
    45361 acatggtgta cgatttcgaa tggatagatg atttctctgc tgcaagaaat ttttcatttt
    45421 ctaaagcttc taaagactat actatgtggc ttgatgcaga tgacataatt ttagaagctg
    45481 atagagaaaa attattaaag attaaagaaa gcttggatac ttccattgat attgttatgg
    45541 caaaatacaa tgtatccttt gatgaaaatg gtaacccaac tctctcgtat tatagagaac
    45601 gattgtttaa aagaagttct aatcataaat gggttgaccc tattcatgaa gtagtacctc
    45661 tttttggaga ggtattttat tctgacattg caatatctca taaaaagctt catagacagg
    45721 accctctaag aaatcttaga atttttgaaa aaatgatttc agaaggaaaa acattggagc
    45781 caagacacca attctattat tctagagagt tgtactataa tgctaggtat aaagaagcaa
    45841 tagaaggttt tactaagttt ttagactcat caagaggatg gattgaggat tgtatcagtg
    45901 cttgcagaga tttagccaca tgttattact taattaatga tgaaaaaagt gccttatatt
    45961 cattgtttag aagtttcgaa tttgatgagc caagagcaga aatttgttgt gacataggaa
    46021 agcatatgtt tgatagacaa aaatataaag aagccatttt ttggtataag gtagcattaa
    46081 caagagataa gaatgatact aatggaggtt ttaagtcaaa tgattgttat ggatatatac
    46141 catctataca attaagtgtc tgttatgaca ggttaggaga atcagataaa gctatttatt
    46201 atcatgaaaa aacaaaagaa atcaaaccta acgatagtgc tgttttgcac aatgaaaatt
    46261 attttagtaa atttaaaaat agttgatagg tcacaatcat actaaatttg acatattata
    46321 tatagagctt aaaagctcaa atatatcagg aggtgctttt aataatgagt agaaataaat
    46381 attttggacc atttgatgat aatgattaca acaatggcta tgataaatat gatgattgta
    46441 acaatggtcg tgatgattat aatagctgtg attgccatca ttgctgtcca ccatcatgtg
    46501 taggtccaac aggcccaatg ggtccaagag gtagaaccgg cccaacaggt ccaacgggtc
    46561 caacaggtcc aggagtaggg gcaacaggcc caacaggacc aaccggtccg actggtccaa
    46621 caggaaatac agggaataca ggagcaacag gattaagagg tccaacagga gcaacagggg
    46681 caacaggccc aacaggagcg acaggagcta tagggtttgg agtaacaggt ccaacaggcc
    46741 caacaggagc gacaggagca acaggagcag atggagtaac aggtccaaca ggtccaacgg
    46801 gagcaacagg agcagatgga ataacaggtc caacaggagc aacaggggca acaggatttg
    46861 gagtaacagg tccaacaggt ccaacaggag caacaggagt aggagtaaca ggagcaacag
    46921 gattaatagg tccaacagga gcgacaggaa cacctggagc aacaggtcca acaggggcaa
    46981 taggagcaac aggaatagga ataacaggtc caacaggagc aacaggagca acaggggcag
    47041 atggagcaac aggagtaaca ggcccaacag gcccaacagg ggcaacagga gcagatggag
    47101 taacaggtcc aacaggagca acaggagcaa caggatttgg agtgacaggc ccaacaggtc
    47161 caaccggagc aacaggaata ggaataacag gagcaacagg gttaataggt ccaaccggag
    47221 caacgggagc aaccggagca acaggcccaa caggagtaac aggagcaaca ggagcagcag
    47281 gattaatagg accaaccggg gcaactggag caacaggagc agatggagca accggagcga
    47341 caggggcaac aggagcgaca ggtctaacag gagcagatgg attagtaggt ccaacaggag
    47401 caacaggagc agatggatta gtaggcccaa caggaccaac cggggcaaca ggagtaggaa
    47461 taacaggagc aacaggagcg acaggtccaa caggagcgac gggagcaaca ggagcagatg
    47521 gagtagcagg tccaacagga gcaacagggg caacaggaaa tacaggagca gatggagcaa
    47581 caggtccaac aggggcaaca ggtccaacag gagcagacgg attagtaggt acaacaggag
    47641 caacaggagc aacaggatta gcaggagcaa caggagcaac aggcccaata ggagcaacag
    47701 gtccaacagg agcagatgga gcaacagggg caacaggagc aacaggtcca acaggggcag
    47761 atgggttagt aggtccaacc ggagcaacag gagcaacagg agcgaccgga gcaacaggtc
    47821 caacaggccc aacaggtgct agtgcaataa taccttttgc atcaggtata ccactatcac
    47881 ttacaactat agctggagga ttagtaggta caccaggttt tgttggcttt ggtagttcgg
    47941 ctccaggatt aagtatagtt ggtggagtaa tagaccttac aaacgcagca ggaaccttga
    48001 ctaactttgc attttcaatg ccaagagatg gaacaataac atctatttca gcatatttca
    48061 gtacaacagc agcactttca cttgttggtt caacaattac aattacagca acactttacc
    48121 aatctactgc accaaacaac tcatttacag ctgtaccagg agcgacagtt acactagctc
    48181 caccacttac aggtgtatta tcagttggtt caatttctag tggaattgta acaggattaa
    48241 atatagcagc aacagcgcaa actcgattct tactagtatt tactgcaaca gcttcaggtc
    48301 tttcattagt taatactgta gcaggatatg caagtgcagg aattgcaata aattagatta
    48361 gataagaaaa ggcttctaat atcgtattga tattaggagc ttttttaaga atgattgatg
    48421 aacatagttt taatattaat tagtgcgcat attataaaat actattatat aatataaaat
    48481 aataacatta aattggaaat atagaattat ctaggggtga tactatgaaa aataagattg
    48541 aaatatcaat gaacaacttt gtaaaaaatt atcataaatc aaataatata actacaaagt
    48601 ggcaagaact tttgtttgct tatgcatctg ctgaagatga tatgtttcag aagctaaaaa
    48661 gtgttgtagg aacatctcat gctatgccaa aagattttct ggaaaatgga aaaactataa
    48721 ttacatattt tatacctttt gatgaaagtg taaataatag taatattgga gggtttgaat
    48781 gttctgaaat atgggcaaga gcgtacatag aaactaatat gttgatttca aatttaaatg
    48841 atttcttatg tgaagaacta gagaagatag gggctaattc atatgctatt cctgggtcgt
    48901 ataattttga cagtgaaaaa ttggtaagtg actggtcaca aagacatgta gcattcatag
    48961 caggtcttgg aacttttggt ttaaataata tgcttattac agaaaaaggg tgttgtggaa
    49021 gaataggaag cataatcaca agtttagaat tagagccaac taaaagacca gaaaatgaat
    49081 actgcttgta taaacataat aatagttgca aaaaatgtgt caacaaatgc gtgaaagaag
    49141 ctttaaaaga agatggattt aataggaata agtgttatga aatgtgtatg ataaatgaaa
    49201 aaaaatacac ttatataggt ggatgtgata tttgtggaaa gtgtatagtt ggagttcctt
    49261 gttcagtaat aaatccatca agataatgga cttaagttga ctaataattt taaagatagt
    49321 ttataatgaa aaaattttag ttatcaaaat aaatataata taaaaactaa ataaatgtgt
    49381 ttaaaaaatg gataaataat ttgtgttgat tgacaaccag ttatactgtt gatagactta
    49441 tatgtatcgc tgtgatatat aaggagggtt gagattttat gtttgattta atctttattt
    49501 ttgcatagca agggctattg caactatgaa atttaatata taaatagccc tttgctattc
    49561 ctaatgaaaa attactattt aataggagag caaaatgagc tataaaaaag caatacatat
    49621 attaccagaa gaattacttg aattaataca ggaatatgta gatggtgaat gtatctatat
    49681 tcctagaaaa tctaataata aaaaagaatg gggaagtaat acacctactc gtgaagagtt
    49741 gtcaattaga aatatgcaga tttacgaaga ctatcaagtt ggatatgatt tgcaatattt
    49801 atcggaaaag tattatttat ctttgaaaag tatccaaaga attgtattac aagaaaaaag
    49861 aaaagatatc taaggatgag ccagtatagt tttataatta tactggctca ttttcttttg
    49921 ataaaagtgt ttgaggtata gtttctttta agtggatgat ataatttaag taatttcaat
    49981 aacttataca gtagctaaca aagctggttg taaagtatct aataagaagt agtagctttt
    50041 tatatgtttg aaattaaaat ttattaaaat taggaggtct tgttttgaaa aaaatacttg
    50101 attatattcc accttttcat aactttctat taatttagta atcttataga aaggaaattg
    50161 catttatgaa aaaaattact tgggaggtgg aatatatctc ccagttacct gtaattaggt
    50221 attgtaaaaa atgtggaaaa aagactgaat atatttgttc aggtttattt agggttaatg
    50281 ctcaacataa atatttggat atatggttaa tatacaagtg ttcaaattgt gattcaacat
    50341 ggaactcaac tatatattct cgtgttaatc caaaaagctt aaatccagaa atactagaac
    50401 aattccatac aaacgattat aatcttgtta agcaatatgc tatgaatatg gaacttttac
    50461 atagaaatgg agcagaagtt ggtattccag agtataaaat agtaggacaa gaaattaata
    50521 ttaatgacct tacacaagtt catattatta gtaaatatcc atgtcagtta aaggtatcaa
    50581 cattattacg tgagaaacta ggtttatcta ggaaggtatt tgacgaaatg ttggattgtg
    50641 ggattattag aagtaactca ggagttgatt taaagaaagg taaattaaat tatgaaatta
    50701 tgttagatat aggcaaggag aagcaaaagt cttcaaattg attagaataa ctaacttaat
    50761 atattttcag gaacatcatt taaaaaaata gtgactttaa aaaatttaaa gccactattt
    50821 tttaatatgt tttatatgag tatttaaaat aaagtgtgta ttcttcaaat ttatagcgat
    50881 aattaaaaca ttactataaa aaggaaggtg catacttttt atttaacaaa aactagatat
    50941 taaaaacttt tcgaggaata ttttattaaa atccctaaat atatttaata tatattaaaa
    51001 aattgtatta taatgaaaat caaaatagat tgcaaatcca aaaagtaata cttaatgtcc
    51061 aaaaagctaa aattaaaatc taaatagcta tttactacag aagtatgtta aaatatgtaa
    51121 aatgaataga aatttatata tttttattaa aaatatataa gaaaggatgt ttaagaattg
    51181 tgattaatat aggaatatgt gatgatgaac tacattatcg aataaaaata aaagatatat
    51241 taagtgaaat attaagttca tatcctataa attataacat atatgaattt tcagcaggag
    51301 aagagttact aaataactat cctaaagatt tagacatatt aattatggac atacaaatga
    51361 aaacaataaa tggtatggat actgctagga agataagaga gtttgatcat aagttagaaa
    51421 taatatttgt tacttcattt gtagagttta tgcaagaagg ttatgaggta aaagcataca
    51481 gatatatact aaagccaata aataaagaaa aaatttctaa aagtgtatta ccttgtataa
    51541 atgagatgat gaaaaagaga aataattact taactataaa tgtaaaaaat tatgtagacc
    51601 gaattaaaat agattctatt acttatatag aaacagatag accgaatata ttgatttata
    51661 cacatgatga tatgtatatt actaaaatga gtatatctaa aatagaaaag atattaaatg
    51721 aatatggatt ttttagatgt cataatagct atatagttaa cttaaaatta gtagaatcaa
    51781 tgagtggaag tactgttata gtagatggaa aaagtattcc aataagtaaa tatagggtta
    51841 aaggcttgaa gcttgcgata actaatatat taggggacat agtatgctaa caaatttaag
    51901 tgtaggattt tggaatatta ttaatttagt ttcaggtact atagattgga ttatattttt
    51961 tttagtaatc cacttagttg gaaagaggaa aatatctaat ataagatata tatttacaac
    52021 aataattata attatattta tggcatacat aaatgtagtt aaagtgtttc caaatattaa
    52081 gattcttcta tgtatggtaa taggaatatc attttatata acatcatatg aagataaaat
    52141 ctataaaagt ataatagtta gtttattgtt ttggctagga ttaatggttg ctgaaggttc
    52201 tgcagtaggt ctagtagtat ttataaataa attaaataat attaacataa cacaacatga
    52261 aaacttattt agaatacaag ctattattat gtcaaaggta tttttattta taggttttat
    52321 attgtttaag tattttaaat tatctttaga ttttaaacct aaagatatga tactaatagg
    52381 aatacctata ttatctaata tagttagctt attacttata tttgaatata atttaagagt
    52441 caatacaatt actacagaaa acttatttat atttatattt gcaattttat tgattttatc
    52501 atcaagtata atacttttaa tagtaatagg gaaaattgta caagacgata aattaaatct
    52561 agagtatgaa cttataaatg aaagaataaa aacaaactac aggaattatg aaaatataaa
    52621 cgaagttcat gatagattaa aatatgttta tcatgacttg aaaaaccata tgatttgtat
    52681 aaaaaattat gacactaaag aagaaattat atcatatata aataacttag agtttcagat
    52741 aagtgaattt gaacatttta aaaatactgg aaataaaaca ttagatttaa ttttagcaga
    52801 aaaaataagt atttgtaaaa agtatgatat tcaaattgaa gataacataa atatatctaa
    52861 attaaacttt attaaaaata atgatatatg ttcaatattt gcaaattcac tagataatgc
    52921 aattgaagca tgtatggata taaataatga gatagaaaaa agaatagaag ttaaagctac
    52981 atatataaat aaatttgcaa taataaaatt tataaatact aaggtaaatg atattaaact
    53041 tattgataaa cgtattcaaa ctagtaagga tgatgataag atacatggaa taggacttgc
    53101 tagtattaaa tatatagtaa ataaatatgg tggtgaaaca atagttaatt actcagataa
    53161 tgagtttata ttaaaaataa tgataccaat aaaaagttag gagagtacaa aatgaaaaaa
    53221 atagcgttaa acttacttaa aaacatctca gcattaagtt ttgggatagc tgtattatca
    53281 gcaaacagtg caagttcttg ggtagcacat caggcaaaag agccacaagc tttacaaaaa
    53341 ctaaaaaaat aacattaata aaaggacctc ttcttattaa aggagaggtt ttacatgttg
    53401 aggaggaaat atgtttaaaa gattatcata taaatttgcc aatatattag ttaataatga
    53461 gattgtagaa agtgaagatt ttgaaatata tagatatgga tttgaaactt tgatttattt
    53521 catagttaat attttggtag cattatttat aggaattatt tttgatagat ttatacatac
    53581 agttatattt ttaagttgtt attgcacttt aagacagttc acaggaggtt atcatgctag
    53641 gaattataaa gagtgtacat taacatttgc agttatttat ttgataacta ttttttcagc
    53701 taataatata gatataaata aatataagta tttattagta ttattaatga ttattagtat
    53761 actaacaatt tacaagttag ctcctttaga acatagaaac aaacctctta gtgaaagtga
    53821 gaaaaagcat tatagaaaga ctgtgcaaaa aatactattc gtaataatat gtttaattat
    53881 tttatgtaaa atacttaata tttttcagca atatgtgatt tatgcaataa tttctatata
    53941 ttggattgct atattaatat atattggaat gaaggttaat agtgatcagt aagattataa
    54001 aacattttct aaattaatta acttcactaa ttaatattaa ctttaaaaaa ataatgtcaa
    54061 ggtaagtatt tgaacttatt aaatatagtt gaatctattg tgggttgtat caaaggacaa
    54121 atagattcac ttaataacca gtttgtaaca gagtattgaa ttgtaaaagt taatacgata
    54181 gtatgaaaat gtaatttgaa attacatttt tataaaaatt atattaacta aggggatgga
    54241 tacatacaat gaatttgaag aaaaaaatta aaaagttagg agttacattt gcaataggaa
    54301 ctataattgt atcaagttta gggacatctg tatttgcaga tgaggttagc acatatgctt
    54361 taatatctaa agctttttca ggtaaaaaca atattatatc tagttcagta tacacttctg
    54421 gaagtagaac ctttaaaacg acagattctc aagggggatt ttcttgtagg ctaacagaaa
    54481 gattctcagg ctctagccca gatagaattg taaaaagaca tgaagcaaat gcttcttcaa
    54541 aagttagttt atcaggagga acatactata taaggtatga aggttcaacg aataatgcta
    54601 aaacatatgc aactttaaat tagtattaaa agcatcctat aattattttt ataggatgtt
    54661 tttgtaattg ttataatcaa aagactggct aggaggggca taaatatgag tagtattaag
    54721 gttatatcag actttataac caaaataatt agaaaaaata ttttatttgc aataacaatt
    54781 attattataa attaccatct catacaacga tggacacata tatccaatag aggaatttca
    54841 tttaatgatt acttatcctt gagtgtatat acttgtatga caattagtat tttaaccatg
    54901 ttaaatgtaa ttttttatat gagaaaaagt tatgatactg taaaaatatt atgtagaaat
    54961 aattttgatt attttttagg tatttctgtt gctgtaacta gaaacaactt tatattttgt
    55021 tgcataccaa ttatatatgc tatagcatac tcaagtttaa taagaacatt gtcaattgta
    55081 acgattaaat caactatatt tatattgata tttgaatggt ttttaccact tactatttta
    55141 tctatagtga tatcatttat ttcagttatt ataaataatt taatactaaa gattacctta
    55201 tcatcagtat ttttatattt aacatcaact aagatgttgg atagagttat tgatattaaa
    55261 gaaccatttt ttaaagcatt atttaaatca cttaacatat ttgaagatca atcatatgct
    55321 tactattctg attttgtagg gaaagttaat aattcagcat atgttataga taaaattata
    55381 cctacactat ttgcaattac tttaataata gtagcatatc tgatattaaa tgatattaga
    55441 aagaaacaga ttaaatcatt aatagttata gtagtgtaca gtattttatt tattggatta
    55501 aattatatat caatagatat gtcaacatat agagatgagg agcgtagtta tggagagtat
    55561 ttaaagaaat ctaatattag tgatattaaa ataaaatcgc atgatatgaa gattgacttt
    55621 aaaagcaagt caaatataaa agatagaatt gttttattaa acacatcaaa tgaagagtta
    55681 acaaatatta atatgatttt agatgaaata tttgatataa aatatataaa agtaaattcg
    55741 gaaaatataa aatttaacaa aaaaaaggat ttaattgaag ttaatttaaa ggaaagttta
    55801 gagcctaatg acgaggtgac attagatata gagtatgaag gctatattaa tgtgttgaca
    55861 tcttggaatc aaaataaata tatagctact aaagatgata ttatgcttcc accaggttct
    55921 ttagcgtggt acccaaaagt aaatcaatca agttgtatgg cttataaaat aaatttaagt
    55981 tctaaaaata atgtctattc aaatttacct ttactgaata agactagtaa ttttttaaaa
    56041 aaagattata tatttgaagg aaagtcaaat gatattgcaa tatatgcagg tgagtttaaa
    56101 gaagaggtaa aagatgatat aaaaataatc tatccatcag atagtaatgt aaatatggat
    56161 atagaggaaa aaattaaatt tttaattgaa acaagaaatg aaatattagg tgatagcaaa
    56221 gcatctgtag atgctaaaaa atatgtagat gaagtagata atgttatgga atcaataaaa
    56281 agaaaaaaaa ttaatatgat attagttgct gacttaccta gtaatgaatt tttatatgaa
    56341 gactcaaagg gagagaaaat tagcataact atttatcatt ggctttcagg aaatatcctt
    56401 ataatagata aataataaag gaggttaata tgataaacaa gttagaaata agaaatctaa
    56461 attttaatta caaaaataaa aaagctttgg ataatataaa tttaacccta atagatggag
    56521 tagttgcatt attaggtcct aatggtgctg gaaaatcaac attaatgagg ttattagtga
    56581 ctctttatga aacttcaatt ggagagatag aattaaacaa tataaagtat agcaaaaaca
    56641 atgagaaaat caaggcaaat gtaggatatg tacctcaaga ttttgatatg tataataata
    56701 taaatgggca agaatactta gaatttgtag ctaaaatgag aggtgtatct aagaatgatt
    56761 taaagaaaca tatacaaaaa gtagtatcaa aagttaatct ggacaagttt ataaataaaa
    56821 aaataggtac atactcaggt ggtgtaaaga gacgactagg tatagcacag gctttaatag
    56881 gtgattctaa gttaatagtt atggacgaac ctacagttgg tcttgatcca gagcaaagga
    56941 atgaatttag aagattgtta ccagaaataa gtaaaaattc tatagtatta atttcaactc
    57001 acatagtaga agacatacaa tttaactgtg acaaattaat tatattaaat caaggcaaaa
    57061 tattatatga tggtacaatt aataagttta ttgatatggt tgaggtgtat tcggtagtag
    57121 tttctaatga tgaatttgaa tatttagaac gtaatattga tattattgat tataggagag
    57181 ttaaagatgg tgtgcaagta aagtatatag gtaaaaatac agagaaactt aaagatagct
    57241 taaggataga tacaacttta caagatgctt atataaactt tttacataag gagttaaaat
    57301 aaatgtgtat attggagtta ataaaatttg agcttaaaaa aatagagctt aaacatgtgt
    57361 taatatttgt aattatttct atattatgca tatttattac aggcatatta gattataatg
    57421 agttaatatt ttataatgat gtacctataa tggatacata ttctatagca ggatggttag
    57481 gaattataaa gatatcagat gtttttatac caataatgtc agcaatcaca ataatttatg
    57541 tgttttcaaa agattattcg ggtaatataa atgagatact tactttatat aataaaaaaa
    57601 aatataatca atttatagta tttagatggt gtgttatatt agctatatat actgtattat
    57661 tattaatttc aattacaata gtatatacat ttacgtcagt gaaaggtttt aacatagaca
    57721 aaatagattt tgtttatagt gtaaagccaa tagatgtgtt tttaaagacg tttcctacat
    57781 tattatggta tacaacattt ccactaatga tattaacatt aacaaaaaat agatttacaa
    57841 caatagcaat attaattaca tatacatttg ctgatatatt ttttatttta catatgtacc
    57901 catttgttag tatgattaat gtaaatggat tttatattca aaagatgttt tatatgccta
    57961 acaatataga tgttagattt aatgaattaa agaattattt ctttataaat agaggttctc
    58021 tagtagttat ttctataata atagtttttt atatagcaag aaaatcaacg gttttaaaaa
    58081 agagtaaata gtttaatata ttttttatat tattatattt atatagaata gtgactttaa
    58141 aaaatttaaa gccactattt tttaatatgt tttatctata taactattat ttttctaggt
    58201 tttttaatat ttcgtaatag tgtgttgtgg ctatttcact tgactcgcct tttttacaaa
    58261 aagataattt ggatagtttt ggaactacac gttcaacgac aattttatta cctatcattt
    58321 tagattcaag tatcttcaat gcttctaaaa atctattatc cttttttgca caattataaa
    58381 atgataaaac gtagacataa aggaataggt tataattacg gaaaggatat tcaacttgca
    58441 taaataatgt gccaattcca tagtgacaag ggccgattgg ttttttaata gtccaatggt
    58501 caagtagaaa atctacagct ttgtcaagtt ttgattcttt atttagataa ttactaaaac
    58561 ggaatgcatt taatatatta agagttggta gtggatttga gtattcagtt tctggacctc
    58621 gaccaaaatt aaatttattg caacgccacc caccatcagt atactgtgta tctaaaaaat
    58681 gttgaaacgt tttttgcatt ctaatgtcag atgcatatcc catatgacag agtacgttag
    58741 cagcatttgc agtatgacaa gggtaaatac ctccatttgg atatagtttg aaacgtccat
    58801 cttctcgcca tgtgctaaat atcaagtcag cacattcttt aagtaaagta tcatcagggt
    58861 tcacacctaa ctctaataga taaagtacac tatcaagagt agagaaagga gaacctttta
    58921 ttaaacgctt atcaggtgta gtccaatagt ctgcaccatt atcatacctg tgtgataata
    58981 ttatttcaat atctgataaa gattgatttt ttactccatt tcatattata ttctattaaa
    59041 tctatcaaaa accttattat aatattattt atatttataa ttgatttatt ttatttaaaa
    59101 ttgcatttat agctgtatca ggaacaactg ctaaatcttc tgcattgaag taataaacta
    59161 tattagaatc aaataatata tttgaatttg gaggaaattc atcatctcca aaccaaagta
    59221 taaatatcat agatgtatta cccatatatg taaacctata agctaaatct cccatgttta
    59281 ctttttcagc tccaattttc tccataacta acttatattt gtctatttga gatgtaaaaa
    59341 cttctgaaag cctatataga gtcctgttta aaaaatttgg ataataaaca ttgcctcctg
    59401 gtatttcttt aaaagttaca tatttattag ttctaggaat acctttagca ttgattaaat
    59461 atctaactat caagatttta agctcaaagt tattgcaaag gctaccatta ctattccaaa
    59521 cttctccact tggatagtct ataatatatt gtctatcaaa aaaattgagt gtgaatctat
    59581 ttaaatcatt attgaaaggt atattactta aattactaat tgtatgaggg tctaattctt
    59641 tgagtttttt tcgaacatag tcaaatggaa cattataatt attttttgtt atcttttcat
    59701 ccataatttt ttcctccaat ttaaacaatt aaaagtatat ttataaaaag ttttcttatt
    59761 attaatttta t
//
LOCUS       DAEPUT010000012        59560 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.012, whole genome shotgun sequence.
ACCESSION   DAEPUT010000012 DAEPUT010000000
VERSION     DAEPUT010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 59560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59560
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.012"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            251..496
                     /locus_tag="KRL22_000889"
     CDS             251..496
                     /locus_tag="KRL22_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH1271403.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            531..1256
                     /locus_tag="KRL22_000890"
     CDS             531..1256
                     /locus_tag="KRL22_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH1271404.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            1278..2591
                     /locus_tag="KRL22_000891"
     CDS             1278..2591
                     /locus_tag="KRL22_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1271405.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYGENLKKIV"
     gene            2797..3336
                     /locus_tag="KRL22_000892"
     CDS             2797..3336
                     /locus_tag="KRL22_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1271406.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            3425..5410
                     /locus_tag="KRL22_000893"
     CDS             3425..5410
                     /locus_tag="KRL22_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HBH1271407.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            5634..6602
                     /gene="spoIIIAA"
                     /locus_tag="KRL22_000894"
     CDS             5634..6602
                     /gene="spoIIIAA"
                     /locus_tag="KRL22_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HBH1271408.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            6592..7113
                     /locus_tag="KRL22_000895"
     CDS             6592..7113
                     /locus_tag="KRL22_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HBH1271409.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            7130..7327
                     /gene="spoIIIAC"
                     /locus_tag="KRL22_000896"
     CDS             7130..7327
                     /gene="spoIIIAC"
                     /locus_tag="KRL22_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HBH1271410.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            7343..7729
                     /gene="spoIIIAD"
                     /locus_tag="KRL22_000897"
     CDS             7343..7729
                     /gene="spoIIIAD"
                     /locus_tag="KRL22_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HBH1271411.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            7814..9019
                     /gene="spoIIIAE"
                     /locus_tag="KRL22_000898"
     CDS             7814..9019
                     /gene="spoIIIAE"
                     /locus_tag="KRL22_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HBH1271412.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            9079..9696
                     /locus_tag="KRL22_000899"
     CDS             9079..9696
                     /locus_tag="KRL22_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HBH1271413.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            9708..10262
                     /locus_tag="KRL22_000900"
     CDS             9708..10262
                     /locus_tag="KRL22_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HBH1271414.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            10289..10978
                     /locus_tag="KRL22_000901"
     CDS             10289..10978
                     /locus_tag="KRL22_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HBH1271415.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDESDSSKTEDSSNIDKQDGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            11088..11450
                     /locus_tag="KRL22_000902"
     CDS             11088..11450
                     /locus_tag="KRL22_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH1271416.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            11535..12041
                     /gene="nusB"
                     /locus_tag="KRL22_000903"
     CDS             11535..12041
                     /gene="nusB"
                     /locus_tag="KRL22_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBH1271417.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            12025..13095
                     /locus_tag="KRL22_000904"
     CDS             12025..13095
                     /locus_tag="KRL22_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HBH1271418.1"
                     /translation="MKLGNNIIIGIDTSYYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            13092..14297
                     /locus_tag="KRL22_000905"
     CDS             13092..14297
                     /locus_tag="KRL22_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBH1271419.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            14299..14514
                     /gene="xseB"
                     /locus_tag="KRL22_000906"
     CDS             14299..14514
                     /gene="xseB"
                     /locus_tag="KRL22_000906"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBH1271420.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            14517..15404
                     /locus_tag="KRL22_000907"
     CDS             14517..15404
                     /locus_tag="KRL22_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBH1271421.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            15434..15871
                     /locus_tag="KRL22_000908"
     CDS             15434..15871
                     /locus_tag="KRL22_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HBH1271422.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            15905..17770
                     /locus_tag="KRL22_000909"
     CDS             15905..17770
                     /locus_tag="KRL22_000909"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBH1271423.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            17903..18715
                     /locus_tag="KRL22_000910"
     CDS             17903..18715
                     /locus_tag="KRL22_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBH1271424.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNRA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            18735..20414
                     /gene="recN"
                     /locus_tag="KRL22_000911"
     CDS             18735..20414
                     /gene="recN"
                     /locus_tag="KRL22_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBH1271425.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKKVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            20628..21494
                     /locus_tag="KRL22_000912"
     CDS             20628..21494
                     /locus_tag="KRL22_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271426.1"
                     /translation="MNKKDTMHLIFTIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QEIMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECVIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDGIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(21587..22078)
                     /locus_tag="KRL22_000913"
     CDS             complement(21587..22078)
                     /locus_tag="KRL22_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1271427.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(22139..22579)
                     /locus_tag="KRL22_000914"
     CDS             complement(22139..22579)
                     /locus_tag="KRL22_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1271428.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            22740..23798
                     /locus_tag="KRL22_000915"
     CDS             22740..23798
                     /locus_tag="KRL22_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBH1271429.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            23940..24764
                     /gene="spo0A"
                     /locus_tag="KRL22_000916"
     CDS             23940..24764
                     /gene="spo0A"
                     /locus_tag="KRL22_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HBH1271430.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            25177..26298
                     /locus_tag="KRL22_000917"
     CDS             25177..26298
                     /locus_tag="KRL22_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271431.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            26316..27191
                     /locus_tag="KRL22_000918"
     CDS             26316..27191
                     /locus_tag="KRL22_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HBH1271432.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            27215..27907
                     /locus_tag="KRL22_000919"
     CDS             27215..27907
                     /locus_tag="KRL22_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1271433.1"
                     /translation="MDSYIGIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            27915..28739
                     /locus_tag="KRL22_000920"
     CDS             27915..28739
                     /locus_tag="KRL22_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH1271434.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            28744..29811
                     /locus_tag="KRL22_000921"
     CDS             28744..29811
                     /locus_tag="KRL22_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HBH1271435.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            29813..30349
                     /locus_tag="KRL22_000922"
     CDS             29813..30349
                     /locus_tag="KRL22_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1271436.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            30417..31022
                     /locus_tag="KRL22_000923"
     CDS             30417..31022
                     /locus_tag="KRL22_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HBH1271437.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            31034..31948
                     /locus_tag="KRL22_000924"
     CDS             31034..31948
                     /locus_tag="KRL22_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1271438.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            31990..33162
                     /locus_tag="KRL22_000925"
     CDS             31990..33162
                     /locus_tag="KRL22_000925"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBH1271439.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKDIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            33209..34021
                     /locus_tag="KRL22_000926"
     CDS             33209..34021
                     /locus_tag="KRL22_000926"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBH1271440.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            34225..35550
                     /locus_tag="KRL22_000927"
     CDS             34225..35550
                     /locus_tag="KRL22_000927"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBH1271441.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            35763..36842
                     /gene="mltG"
                     /locus_tag="KRL22_000928"
     CDS             35763..36842
                     /gene="mltG"
                     /locus_tag="KRL22_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBH1271442.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFLYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            37014..37688
                     /locus_tag="KRL22_000929"
     CDS             37014..37688
                     /locus_tag="KRL22_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBH1271443.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            37675..38922
                     /locus_tag="KRL22_000930"
     CDS             37675..38922
                     /locus_tag="KRL22_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH1271444.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIIVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            38994..40658
                     /locus_tag="KRL22_000931"
     CDS             38994..40658
                     /locus_tag="KRL22_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBH1271445.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(40755..41396)
                     /gene="sigK"
                     /locus_tag="KRL22_000932"
     CDS             complement(40755..41396)
                     /gene="sigK"
                     /locus_tag="KRL22_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigK"
                     /protein_id="HBH1271446.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTP
                     REREIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            41963..42325
                     /locus_tag="KRL22_000933"
     CDS             41963..42325
                     /locus_tag="KRL22_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271447.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            42309..43025
                     /locus_tag="KRL22_000934"
     CDS             42309..43025
                     /locus_tag="KRL22_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271448.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVGGFTEEDEEYEEELKQNIIE
                     NIKKNFDEKNLVQVYKYRGV"
     gene            43045..43464
                     /locus_tag="KRL22_000935"
     CDS             43045..43464
                     /locus_tag="KRL22_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271449.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            43454..43978
                     /locus_tag="KRL22_000936"
     CDS             43454..43978
                     /locus_tag="KRL22_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271450.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            44290..44847
                     /gene="efp"
                     /locus_tag="KRL22_000937"
     CDS             44290..44847
                     /gene="efp"
                     /locus_tag="KRL22_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBH1271451.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            44939..45394
                     /locus_tag="KRL22_000938"
     CDS             44939..45394
                     /locus_tag="KRL22_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1271452.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            45557..46267
                     /locus_tag="KRL22_000939"
     CDS             45557..46267
                     /locus_tag="KRL22_000939"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBH1271453.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            46321..47391
                     /locus_tag="KRL22_000940"
     CDS             46321..47391
                     /locus_tag="KRL22_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1271454.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            47419..50973
                     /gene="smc"
                     /locus_tag="KRL22_000941"
     CDS             47419..50973
                     /gene="smc"
                     /locus_tag="KRL22_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBH1271455.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEIKDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLESSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            51000..52280
                     /gene="ftsY"
                     /locus_tag="KRL22_000942"
     CDS             51000..52280
                     /gene="ftsY"
                     /locus_tag="KRL22_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBH1271456.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDVEEKNEESVNNEGTEEIENFEKIEVEMNSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            52383..52751
                     /locus_tag="KRL22_000943"
     CDS             52383..52751
                     /locus_tag="KRL22_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBH1271457.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            52748..54100
                     /gene="ffh"
                     /locus_tag="KRL22_000944"
     CDS             52748..54100
                     /gene="ffh"
                     /locus_tag="KRL22_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBH1271458.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            54138..54410
                     /gene="rpsP"
                     /locus_tag="KRL22_000945"
     CDS             54138..54410
                     /gene="rpsP"
                     /locus_tag="KRL22_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBH1271459.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            54475..54702
                     /locus_tag="KRL22_000946"
     CDS             54475..54702
                     /locus_tag="KRL22_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBH1271460.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIILKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            54810..55325
                     /gene="rimM"
                     /locus_tag="KRL22_000947"
     CDS             54810..55325
                     /gene="rimM"
                     /locus_tag="KRL22_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HBH1271461.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            55334..56029
                     /gene="trmD"
                     /locus_tag="KRL22_000948"
     CDS             55334..56029
                     /gene="trmD"
                     /locus_tag="KRL22_000948"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBH1271462.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKYIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYILTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            56214..56564
                     /gene="rplS"
                     /locus_tag="KRL22_000949"
     CDS             56214..56564
                     /gene="rplS"
                     /locus_tag="KRL22_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBH1271463.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            56885..57781
                     /gene="ylqF"
                     /locus_tag="KRL22_000950"
     CDS             56885..57781
                     /gene="ylqF"
                     /locus_tag="KRL22_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBH1271464.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            58170..59462
                     /gene="brnQ"
                     /locus_tag="KRL22_000951"
     CDS             58170..59462
                     /gene="brnQ"
                     /locus_tag="KRL22_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH1271465.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT        24490 a         5869 c        10947 g        18254 t
ORIGIN      
        1 aatattgtaa tttataatta aatattaata ggtttttaaa ataggattag ataggtaata
       61 ggttaagtta gaataaccca ttacctattt ttatttgtaa gaaaagtgta catagaatta
      121 gaagtaaaaa atacaactaa taaaactatt gaaaatacta gataaataat aaataaaaat
      181 aattatagat tttggcatac atattgctaa ttatagagat aagacgacaa aataattggg
      241 aggtttaatg atgaaataca aaacaacagg gacttgtgct acagaaattg aatttgaagt
      301 aaaagaaaat aaagttacaa atgtaaactt tataggtgga tgtgatggaa atttaaaagg
      361 gctaaaagta ttagttgaag gcatgaatat agaagatgta atacaaaagt taaaaggaat
      421 agagtgtaaa acaaagccaa catcttgccc agaccaactg tctctagcat tggaaaatta
      481 tatgaatata aagtaataca taaaacaatc gattagttag gagtttaatt atgaaaccaa
      541 taatagggat tttaggaaat ttaataataa tggaaaatgg tatgtttcca ggtcttgaaa
      601 ggtcatatgt aaataatgat tatataaatg cagtgctaaa aggtggcggt agtccagtaa
      661 taattcctgt aaatacagat aaagaagtta taaaaaaaca gattgaaatg gttgatggag
      721 tcttaatatc tgggggatgg gatatcaatc ctcaactgta tggagaagaa acaagagaag
      781 aaacgacatt tatatatcca gaagtggatg aatttgattt aattgcaata agtatagcat
      841 tagaacttaa aaagcctata ttaggtgtat gtaggggact acaaatttta aatgtaagtt
      901 taggaggaac tttatatcaa gataataatc ttatagaagg aagttatata aaacatacac
      961 aatcttctaa aagacatgta gctactcata aagttgatgt taaagaagga agtattttag
     1021 agggaatttt aggaaaacaa ttacttacaa atagttatca tcatcaaagt gtcaatcagc
     1081 ttggaaaagg attaaaagcc atagcatact caaaagatgg tataatagaa gctattgaga
     1141 aagaggatga aaattttgta gtaggagtac agtggcatcc agaaatgatg gtagattact
     1201 gtgataaaat ggaaaaacta tttaaatatt ttataaatat ttgttcaaat ttataatata
     1261 ccttgggggg attgaacatg aacgaaaaga ataaaatggg attaataagt attatacttt
     1321 taggtattaa tgcagtagta ggagctggag tttttctatt accaggagat gcaatgaaat
     1381 catttggtgt agcaagtata tttgtatata tatttgatat gttgttagtt ttatctatgg
     1441 cattctgttt tgctgaggtt gcaggtaaat tcaataaaaa tggtgctgcc tatgtatata
     1501 caaaagaagc ttttggagat ttttgtggtt ttgaagtagg tcttatgaaa tgggtaatag
     1561 gatgtatttc ttggggagct ttaatagtag gttttcctac atcattatca gcagtatggg
     1621 ctccagcagg tgaaccacat atacaaaaaa ttataattgt agccatgata gttgggctta
     1681 caattataaa cttattaggt gtatctctat caaaaattgt acaaaatgtt ataactgtag
     1741 gtaaactaat tccattaata ctatttatag gaataggtat attttttata aaaggagtta
     1801 attttacttc ttcaacaatg gtacctccag gagctggagc aacagagttt ggagcagcag
     1861 cacttttaat gttttattca tttacaggat ttgaatctat agcagttgca gcagaagata
     1921 tggagaatcc acaaaaaaat ataccaatag caattataag tgtaatagta attgcatcaa
     1981 taatatatat attaaatcaa gttgtatgtg ttggtatact aggagattcg ttatctagta
     2041 catctacacc agtggcagat gctgcaagaa tatgctttgg aaatatggga gctggattgg
     2101 ttacctttgg aaccttggtt tctgttggtg gaatttgtat gtgtggtgct tttgtaaatc
     2161 caagaagttg tgtagcttta gctgatgata aaatgttacc gagaatattt gcaagaaaag
     2221 ataaaaaagg tacaccatat gtagcgataa tagctactat gctaatcact ataccaatag
     2281 ctctatctgg aagttttgct gaattagcag caataagtgc agttgctaga ttcatacaat
     2341 acataccaac atctttatcc gtattagtgt ttagaaagaa aagaccagaa ttagtaggta
     2401 cttttaaaac tccttttgga gcagtgattc ctctaattgc tgtatgtgtt ggaacatggt
     2461 tattattcca agcatctatg catcaattaa ttatgggatt aggagctttg gcaattggag
     2521 taccattata ctttataatg aagtcttata atagaaaagt ctatggtgaa aatttaaaga
     2581 aaatagttta attatgttat aacagtttat tgagttaaaa ttagacattg gcagaaaatt
     2641 aaatacaaat aagtatctat aaggctatat taaaatatta ttaatttttt attttaatat
     2701 agccttaaat tgttatcaat aagtgaaaaa tattgtaaca atagaagaac aatagtttta
     2761 tgtttataga caaaaaactt attaggaggt aaatttatgc caacaataac attaaaaaat
     2821 ggtgtagacg tacttattag agaaggagta agggaagatg ctcaaagcat tatagatttt
     2881 tataatgaag tgggtggaga aactcatttt ctgtcatttg gaaaggatga atataaaata
     2941 tctttggagg aacaagaaaa tgctatagaa tcagcaaaag catctgataa ttctgttaaa
     3001 ctgattgcat ttatagatgg tgaaatagtt ggaattgcaa cgattgattc taatcaaaaa
     3061 gcaaaaggaa agcatgttgg agtattagga attgttgtaa aagaaaaata ttggggaatt
     3121 ggattgggta aaaggcttat gttagacctt atagaatggt gtaaatcaaa tggaataacc
     3181 aagaagataa ctcttgtcac taatgaagaa aattataatg ctataggatt atacaaaaaa
     3241 gttggatttg aagtagaaag catactaaag aaagaatgtt attataatgg tgtttatact
     3301 gatttaatag gaatgtcact tttattggga atataattag tgtacacttt atctcgaaaa
     3361 aagtatatta agtatggtat aattaaaaaa gaatataact taatataatt ttggaggacg
     3421 aattatgaaa aatctgtgta aaatatcaga tgattattta aacagcaagc ttaagtattt
     3481 aaagttatta tcaaaacaat atccaagtat atcaaaagca agtacagaaa taataaattt
     3541 agaggctata ttaaatcttc caaagggaac agagcatttt ataacagatg tacatggtga
     3601 atatgaacca tttgtacatg tattaaaaaa tggttctggt gtaataaaga gaaaaataga
     3661 agaattgttt tcaaatacaa taagagacag cgaaaaaaaa atgttagcaa ctcttgtata
     3721 ttatcctgaa caaaagttag acctaataat taagcaagag gaaaatatag atgattttta
     3781 tagaataaat atttatagac ttatagaact ttgtaaatat gcttctagca aatatactag
     3841 gtctaaagtt agaaaactgt taccagaaaa ttttaaatac ataatagaag aacttttgca
     3901 tgagcatgtt aaaagtgaac ataaagaaga gtattataaa agtatagttg aaacaatagt
     3961 tgacatagga atagctaagg agtttataat tgctatttct acagttatac aaaaattggt
     4021 tgtagataga cttcatgtaa taggagatat ttatgataga ggtccaagac cagatataat
     4081 tgtcgataag cttattgaac atcattgtgt agatattcaa tggggaaatc atgatatatt
     4141 gtggatgggt gcagcctcag gtgaaaaaac ttgtatagca aatgcactga ggatatcagc
     4201 tagatatgcg aatttagaca ttgtagaaga catatatgga ataaatctgt tgcctttggc
     4261 cacttttgct atagaaatgt ataaagatga cccttgtaaa gaatttattc caaaggttaa
     4321 tgaccaaagt gtaacaacaa cagaaaagtc tttaatggca aaaatgcaca aagcaataag
     4381 tataattcaa tttaagcttg aaggtgaggt tatcagacga agacctgaat ttgaaatgga
     4441 acatagactc ttgcttaata tgataaacta tgatgaaggt acgattaatt taaaaggtaa
     4501 aacatataaa ttaaaagata cttatttacc tacaatagac aaaaaagacc catataaatt
     4561 aactatggaa gaaagaaatg ttattgataa attagtatct tcatttagag gtagtgaaaa
     4621 attacaaaaa catgtttcat ttttgttttc taaaggaagt atatatttaa aggctaactc
     4681 aaatttactg attcatggat gtgtaccgtt aaatgaagat ggaagcttta tgtctatgaa
     4741 tataatggga aaagagtata aaggtaaggc tcttatggat aagatggagt ctctagcaag
     4801 agaaggattt ttctttaaag ataaggcaga agaaaaactg tatggcatgg atattatgtg
     4861 gtatttatgg actgggaaat gttcatcatt atttggtaaa gatgatatga ctacatttga
     4921 aagatacttt atagctgaaa aagagactca taaagaaaat aagaacccat attttaaact
     4981 tagagaaaat gagatggctt gtaaaagatt atttgaagaa tttgatttag aacttgatga
     5041 atctcatata ataaatggtc atgttcctgt ggagagtaaa aatggagaga gcccaataaa
     5101 agctaatggt aaaattcttg ttatagatgg tggtttttct agggcttacc aaaaaactac
     5161 tggtatagct ggatacactt tgatatacaa ttctagaact ttgcaattag tatcgcatga
     5221 accatttaat tctgctgaag aagccattgc aaatgaaagt gatatcttat cgacaactgt
     5281 tgtagtagag cataaggcaa agagaaaaat ggtgagagat actgatgaag gagtaaagat
     5341 acaagaggaa atagaagatt taaaactact tttaatggct tataagaaag ggctaataaa
     5401 agaaatgtag atgttataga ggcacttcat gattgaagtg tctttttgtt aatacttatt
     5461 aaatatatta taaagattaa taatagtagt ttatattata cttactaagt gaatccaaga
     5521 taaatgggtt cacttttttt atttataaac attattaaaa aaatatagat gttttggtta
     5581 tattccttgt cctttataaa tagaattata taaacaaagg aggaggacaa gagatgaata
     5641 aactttctga tgaaataata aactctcttt ctacaactat aagagaaaag gtagaaaaag
     5701 tctcaaacaa taatctgaac atagaagaaa ttaggttacg ctcacaaaaa ccattgatac
     5761 taaatgcaaa ctctaaagat tatttttaca atcaaaaaac tatgacactt gatttaaatc
     5821 aacaaaactc atatgtagta acaagagaag atgtagagca aacttttcaa ataatatgta
     5881 aatattcaat acattcattt atggatgaca taaaaaaagg attcataact ttgagaggag
     5941 gtcatagagt agggttagtt ggaaaagcaa tagtagaaga tggacaagtc aaaaatataa
     6001 agcatatatc atctttaaat ataagggtat caagggaaat tattggatgc tcggataaga
     6061 ttttaagtca tatcataaag ggaaaaaatc agattaataa tactttgata atatcaccac
     6121 ctcaatgtgg aaaaacaact ttaataagag atatagtaag aaatttaagt aatggtaatg
     6181 aagattatgg atttaaaggt ttaaaagtgg ctttagtaga tgagcgtaat gagatagcag
     6241 gagcttatct aggtgttcca caaatggatg tgggaataag gactgatata atagaaactt
     6301 gcccaaaaga cttgggtatt acaatgcttt taaggtctat gtcaccaaat gttattgtga
     6361 cagatgaaat tggaagtgaa aaagaaataa aggcattata cacagcatta aatggaggta
     6421 taggattaat aactactgtg catggagatt caatagagga tatacaaaat agaaaagaat
     6481 taaatagact tctggataaa gagttattta aaaaggttat aattctttct gcaaaaagag
     6541 gagcaggaac aattgaaaaa atttatgatt tagaagaaaa gagatggtat tttgcaaatt
     6601 aaaataatta ttatagcttt cttgatagga agtagttatt tgataggtga acaaatatac
     6661 aaaacttata ctcgtagaca taaacaatta aacgatttaa taagagtttt agaaattttg
     6721 aggatggatt tatcttttgg actttataca ttagaagaaa tctttaatag gataggtgga
     6781 aataaagagt tttgtttttg gaaatttttc tatcaaatat cagaaggact tcacaatgaa
     6841 caaagtaaaa ctttggaaat aataatatca gaaaatattg atgtcttaag taaagaaact
     6901 tatctaggca ataaagaaat tgaggaactg aaaaatctaa tacttacttt agggaaaagc
     6961 gatatagagt cacaacaaag aatgatagat ttatctatag aaaatttgaa aaaacaaacc
     7021 tatgagacaa aggaagatat aaacaaaaaa ggcgtattgt ataaaaaatt agtgacattc
     7081 ataggtatag gtatatgtat tatattgatt taatatgggg aggtttatta tggaaatatc
     7141 attgatatta aaggttgcag gtgtcggtat tctaatatca gtattgaata tgatattgga
     7201 aaaaacagat agaaaagatt gggcaggtct tactacatta gcaggtgtaa taatcgtatt
     7261 gggtatggta ataacagaaa taagtgactt gtttaatact gtaagaacaa tgtttcaact
     7321 ttactaaaga ggagggagta atttggaaat aatgcaatta ataggaattg caatcatttc
     7381 aactacactc tgtttagtaa ttaaaaaaga tagaccagag atagcaaatt tcatagctat
     7441 aataactgga gtaataatac tattgtcagt tatgtttaag ctaaatttta tagtagatag
     7501 tatacaagat ttggctaaca aggctaacat cccgactatg tatatatcat taataataaa
     7561 attaattggg atagcatact taatggaatt tgcgatacaa ctttgtaaag attgtgggga
     7621 aggaaacatt gcttcaaaac tagaatttgg aggtaaaata atagttatgt caatgtcttt
     7681 ccctatactt ttgtccattg tagaaatggt ggtgaatata attccataga tgtgtatctt
     7741 ggaatgaata taagtatatt agagagcttt cgttgtattg aggtttatag agtgaagaga
     7801 ggcatggttg cttatgaaaa aaagattttt accaatgatt ataggttttt tatttacttt
     7861 cttttttgta aatatctttg ctattatgat atttgctaat gaagtaccaa gtagtgaaga
     7921 taaagaatat ggtgaaacaa aaaatagcat agataagtat atagatggtc aattagacaa
     7981 gctagatata aatgagattc aagactatat aaataaagaa atagttatta atgatgttaa
     8041 tttaaaatca tttgtaaaag atttaattag tggagaaaaa aatatcttag atttattcaa
     8101 taaagatgga ttgaagatat tgatgtttga tgaatttaaa gcaagtttaa aggtagtagc
     8161 agtaattttg gtactggctc tgctatcatc tattttaaag agtctggaaa actctttttc
     8221 atcaggtgca gtaagtcaaa tagcaacata tataatattt atcacaatgg tatcacttac
     8281 acttattggt tttaaagatg tattacagat ttgctatgat gcaatagacc atactgtagg
     8341 tcttatgcaa gttataatgc caatattaat aacattttta cttttaattg gattcccaat
     8401 aacgtcgact actttgaatc ctatcttcat aggaggagta acatttataa atgtattttt
     8461 taaaaatttt ctatttgtat ctattactgt tgcatttgga attttaataa taaacaattt
     8521 atcaaaaaat ataaggctaa agagattttt ctcctttgta aaacaaataa attatgtttc
     8581 tattggagct atgtttactg tttacttagg tcttgtatcc atacaaggac tgtatgtaac
     8641 cagttttgat aaattcagtg taaagactgc taaatttgct ataggtaatt ttattcctgt
     8701 tgtaggtgga tttgtatctg actctgtgga tattttatta tcttcatctc agcttataaa
     8761 aaatatattt ggaggaatag ggcttatctt acttgttgga atttgcttac ttccagtaat
     8821 aaaaatttta tcagtaatag tagtgtacaa attagcagca ataattgtag agcctgttgg
     8881 agaggatgga atatctaatt ttttaaatga agtggcaaat ttaatgataa taatgctagc
     8941 atcagtaatt gctataacag taatgttctt tgtaactgta gctatcttga cctcgataag
     9001 tgtcgtaagt caagggtaat ttatatatca gtgaaaaata attacattta atctaatgtt
     9061 tttagagagg aggatgctat gttagagggc ataaaggcat ggatagttag tgttttgata
     9121 ggagcattta tagtaaatat agtagatatg attttaccaa gttctaagat aaaaccttat
     9181 gtcaacctag ttttaaactt tatgtttgta tttattgtaa taactccagt agtaggattt
     9241 ttttcaaaag atatgagttt agaagataga atattaaaat ctatgggaaa ctacaacaag
     9301 cagtatgtag atagtacaaa tgctttggca aaagagactg gaaataatag tctatccaag
     9361 ggatatgagg atgggttaaa agaagtactt aaattaaaac ttgatgaata tggttatgat
     9421 ttagaagata tagagcttaa tggggcaaat ataaataata taaaaataaa agaaaagaat
     9481 aatagtgcaa aaagtaataa cagttccaat gaagaaaata aaaataatag tactaaaaga
     9541 gaggaagaaa acataaactc taatgacaaa gaaaattcta aacaagtctt caaaaaaggt
     9601 acagagtatg ggttgaacct aaatgaagaa aaattaaaaa acgacttaat aaaggtgctg
     9661 gatgtttcta tagaagatat acaaattgat aaataggagt tgggagaatg ttgaaaaact
     9721 taaatgacaa agataagaga aaggtatatt cactaataac tatagcagga atatgtgtgg
     9781 tttcattagt attattatct tgttttccta gtagcaaaag cgataaacaa gttggaaaaa
     9841 cagagactaa taaaaatgct gaaaagcaag tcactaaaga acaagaaaaa gatgatttag
     9901 agtcaaaatt aacagcaata ctatctaaaa ttgatggtgc aggagacgtt gatgtaatgg
     9961 ttacatttga atcaagtgaa gaaatacaac ctgcttttaa ttcaaataat acaacagaaa
    10021 caacagagga aaaagatgca caaggtggag aaagaacagt tacgacttct agtgaaaata
    10081 aaacaatgat aacttcaaat tcaagtgacc ctgtagttat aaaaactaca gagccaaaga
    10141 taaagggagt gatagtggta gcaagtggag caagtgaccc aagtgttaaa gagacacttt
    10201 atagtgcagt acaaacatca ttacaagtag ctggtcatca agtagaaata tattctaaat
    10261 aaatacatat aaccgggggg ataaatgaat gaagtttaat tataagggaa gaggatttgt
    10321 aataataact ttaactgcaa tgttagtggt agtaggaaca gtgaattatc aactaagtaa
    10381 gaaatcttta ttagaaacat caaaagagtt taaggcatat gaagaagcac agttgcaaaa
    10441 aaatactgat gagagtgata gtagtaagac agaggattct agtaatatag ataaacaaga
    10501 tggtaaggaa agtgctgata ttgatatagt tgatagcaaa gctagtaaag taaaagaaaa
    10561 ggcaactgag acaagtaagg aaataaaagc tcaattatca tcagagaaaa atatgaaaaa
    10621 ggcatcttat attttagata tgaaaatgaa tagagaaaaa caaagaaatg agttagttca
    10681 agatttaaat gaaatgataa ataatccatc tacaacagaa gaatctagaa aagaagcttc
    10741 taatatgaaa ttaaatatag ttaaaattca agaaaaagaa cttcaaatag aaaacctttt
    10801 gagtacaaaa gggtatgaag aagcgttagt ttatataagc gataacaaag ttaatgtagt
    10861 tgtaaatgaa gctaaattag aaaagaaaga tgcagcaaaa atatttgatt tagttgcaga
    10921 acaagccaat gtgaagtatg aaaatattaa acttacaaat aataatagta ataagtaaag
    10981 tataaacctc agaattaact gaggttattt tcttgcaaag tagacttgta tttggtatta
    11041 ttatacttat aaaaatagtt ccttaaaatc aggaggtaag ttttaatatg gaagataata
    11101 aatttggaca agtaaaaata tctaatgatg taatagctac aatagctggt ttagcagcat
    11161 tagaagttga aggcatagaa actacagcaa cattaacaga taagttgtta aaaaataatg
    11221 gagtaaaaat acaaatcgaa gaagaggatg ttaatttaga tgtaatggtt acgataaagt
    11281 atggaatgtc aataccagat acagctttta aagttcaaga aaatgtaaaa aatactgttg
    11341 agacaatgac aggactgaag gtttctcaag taaatataca cattcaagga atcagcttta
    11401 agaaggataa agttgataaa gaagaagcaa aagcaactaa gaaaaattaa tattagccct
    11461 ctgaaaagtc agagggtttt ttgctggtaa ttgattttat atggataatt aaacttaaag
    11521 gagaattttg attgatgaaa aaagataggg cacaaaagag tacaacaaga gaatatataa
    11581 tgaaacttat ataccaaata aatattaata aagaagattt tgaaacttta gaagataaag
    11641 tagataattt tttaaaagat aattcagaac atattataaa tagatataaa gaacttgcac
    11701 ttcaatactc aaaaaataca aatttaaagt tagaagatac tgaaattgaa gatgttatag
    11761 acaaaaaata tataaataca gtatgcaaag cattgaaaga aaatcatgac aaaatagatg
    11821 agttaataaa taagcatgct aaaaactgga cagtagatag aatgccaaag gtagatgttt
    11881 ctatacttag attgtctgtg tgtgaaatac tttatttaga cactcctaat aaagtatcaa
    11941 taaatgaagc agtagaactt gcaaaaatat attgtgatga taagtctcct aaatttataa
    12001 atggtatatt gggaagtgtt gttgatgaaa ttgggaaata atataataat tggaattgat
    12061 actagctact atactacttc tatagcagct atctctttag ataagaaagt tatattcaat
    12121 gaaaaaataa tgttagaagt aagggataat tcaaaaggtt taaggcaaag tgaagctgta
    12181 tttcaacata tcaataattt agggattctt agtgatagga taaaatcttt taaagataag
    12241 tttaatgtag aaggagtttg ctcatcaaaa aaaccgagac ctgttgaaaa ctcatatatg
    12301 cctgtattca atgtaggtca taattttgga aaattattgt ctagtatata tggttgtagg
    12361 ttttatgaga ctactcatca agagaatcat attgaagcaa gtttattaaa tagtaaatta
    12421 aaaaataata ataaatttat ttctgttcat atgtctggtg gtactacaga gatactttta
    12481 acaagcaaac aagatagtca tcacaatgta tgtgatacta atttaggtaa aattgccaaa
    12541 ataagtatta aaaaagatga taaaagtaag ttatacaata attttggata taatatagat
    12601 ataattggag gaagtaaaga tattagcttt ggtcaactta tagatagagt aggaattaag
    12661 cttggatata aatttccttc aggaaagtat ttggatgaaa atgctttaaa ttgtaatctt
    12721 aaaatagaaa gtggtctgaa aacttctgta agagatgggt atatgaattt atcaggatta
    12781 gaaaatcagg taaataagat tataaatgat aatggagata atactaatca aaaagaatat
    12841 atatctaaat tagtattaga ttcagtagtt agaaatatgt ttaaatctct agtgtattta
    12901 tgtgaaactt ataatgtaaa tgaagtagta tttgctggtg gagtttctgc aagtaagtat
    12961 attcttagag aattaagcat gaagttaaga aaaaagcata tagaagctta ttttacagaa
    13021 ccacaatatt caactgataa tgctgtcggg tgtgctataa taggattgaa taacttttta
    13081 ggagaaagag tatgaaacta agagctttag atataagtga agcaaactca tatattaaaa
    13141 gaattttaat aaacgaccca atactttcta atcttaaagt taaaggagaa atttctaatt
    13201 ttaaggttca tagtagtggg aatgtatatt tatcacttaa agatgaaaca tcaaagttaa
    13261 actgtgtaat ttttaaaagt aattttaatc gcaatttaaa attagataat ggtgtaaaaa
    13321 ttatagctaa tggatatata tcagtctatg aaagagatgg tgcgtatcaa ttatacatta
    13381 atgaaattga aatagaggga ataggaaatt tacacataga gtttaataga ttaaaggaaa
    13441 aacttaataa agaaggatta tttgacccta aatacaagat acctatacct aaaatgccaa
    13501 actcaattgg agttataaca tctccaacag gtgctgttat aagagatata ataaatgtaa
    13561 taaaaagaag atatccgaaa gttaatataa agctttatcc agtaacggtt caaggagata
    13621 aatcagctga agaaatctgt gaagcaatta gatttttcaa tcatatgaag aatgttgata
    13681 cacttatagt tggtagaggt gggggttcaa tagaagaact ttggtctttt aatgatgaaa
    13741 tggtagcaag agaggttttt aattctcaaa ttccgataat atcagcagtt gggcatgaaa
    13801 cggattttac tatttgtgac tttgtgtctg atatgagagc cccaacgcca tcagcagcag
    13861 ctgagattgc tactccatca ttggatgata taaactataa acttggaaac ataaaaagta
    13921 ggatgagtaa gtctcttaca aatcaaatag agctagacca atataggtta gaaacagtat
    13981 ttaataagat aaataactat ttagattcgt acacaataaa agataaagtt atacaattag
    14041 acaaaatata tgataaaata atttttggaa tagaaaataa tttaaaatta gaagatgaaa
    14101 aattagtaaa aattggagca ttactccata atttaagtcc attagctact atggatagag
    14161 gttatagtat aactcaaaaa aatggaaaag taataaatag tataaaagga ttaaaaataa
    14221 aggatagtat agatatagta ttaaaagatg gaaatttaga atgtatgata gataaaattg
    14281 aaaataaaga gggatagtat gaatttaacc tacgaagaag cttataaaag attagaaagt
    14341 attttaagtg aattagaatc taaaaatgct agcttggatg aatctttaag cctatatgaa
    14401 gaaggtataa gcctttataa acattgtaat aagcttttag atgatgctaa attgaaaata
    14461 agtaaattta atcaattggg aatagaagaa gactttaaaa tagaggagga ataaaattgg
    14521 aatttaaaca atgtctaaaa gaaaaagcaa gttttgtaga aaaagtactt aaagaatata
    14581 tgcctaaaga agaagggtat caaaaaactg ttattgaagc tatgaactat agcttaagtg
    14641 ctggaggcaa aagattaaga ccaatactta cattggaggc ttgtaaaata gttggaggta
    14701 atgaagatga agctattcct tttgctattg caattgaaat gatacataca tattcactaa
    14761 tacatgatga tttgccagct cttgacaatg atgatttaag aagaggaaga ccaacaaatc
    14821 ataaagtata tggagaagct atggggattt tagcaggaga tgctttgtta aactatgctt
    14881 ttgaagtaat gcttgcaggc tcaatcaata aagaaaatcc agaaaagtat ctaaaagcta
    14941 taaatgaaat tgccaaaggt gctggtatat atggaatgat aggtggtcaa gtagtagatg
    15001 tagaaagcga aaataaacaa attgaaaaag aaaaattaga ttatatacat atgaataaaa
    15061 ctgctgcaat gatggtaggc tgtatgagag caggagctac tataggtgga gcaaattctg
    15121 aacaaatgga agaaataact aaatatgcaa aaaatatcgg attatcattc cagatagtag
    15181 atgatatact agacatagta ggagatgaag ctaagttagg taaaaaggtt ggaagtgata
    15241 tagaaaatca taagtcaaca tacccatctc ttttaggttt agataaatct aaagaaattg
    15301 cacataattt gattgatgaa gcaaagaaaa gtatagaaaa attatctgat gatgtagatt
    15361 ttttaaaggg attggctgaa tatataatag atagagaata ctaaaatata cagctaaaat
    15421 cgaggaggga aaaatggatt ttttttcgga gatttttaac aatggggctt tgggaataag
    15481 tctgattgct tgtttcttag cacaatttat aaaaatattt actggtaagg aaaaaagaat
    15541 tgagttatca agaatactta tttcaggagg tatgcctagt tcccatagtt cttttgttac
    15601 aagtttagct acagtggtag gtattgaaaa agggtttaat tctactgatt ttgctataat
    15661 taccgtgctt gccttaatta taatgtatga tgcagcaggt gttagacggg ctgttggtaa
    15721 acaagctact atattaaatc aaatggtggc agatatacag catggaaagc atatagagca
    15781 gaagaaatta aaagaattaa taggtcatac accactagaa gtttggtttg gagctttact
    15841 tggaatagta acagctttaa tattgatgta aattgaaaat ttacagaata aaggtgagga
    15901 taatatgtat aaatatttag ataaagtaaa ttctccaaag gatataaaaa atatgagtat
    15961 agaagaaatg gatttacttg caaaggatat aagaaagttc ttagtaaaat ctgtttcaaa
    16021 gacaggagga cacttagctt ctaatctagg agtggttgag ttaacattag cacttcataa
    16081 agtatttgat agccctaaag ataagattgt atgggatgta gggcatcaat cttatgttca
    16141 taaaatagtt actggaagaa aagattgttt tgtatctttg agacagttta atggactaag
    16201 tggttttcca aaggagaatg aaagtcctca tgatattttt gatacaggac atagcagtac
    16261 atctatttct atagctacag gtattgcctg tgctagggat ataaaaaaag aaaactatag
    16321 tgttatatct gtgataggag atggttctat aacaggaggt atggcacttg aagctttaaa
    16381 tcaattagga tatatagata ccaatatgat agtaatcctt aatgataatg agatgtccat
    16441 agataaaaat gttggaggaa tgtctaaata tctgtcaagt attataagaa actcaacagt
    16501 tgagaaaatg acagatgaag ttgataaaat tttaaatgtt acacaaacag gtgaaatttt
    16561 atctaagact gcacatagat ttaaagataa actaatgtat agcttttctc ctcaggactg
    16621 ttcatttttt gattcattag gtataagata ttatggacct atagatggcc ataatactaa
    16681 agaactaata gatatattga gaaaagctaa acacaaaaaa gggcctgttc ttttacatgt
    16741 aattacgaaa aaaggaaaag ggtacagatt tgcagaagaa caacctgata aatatcatgg
    16801 agtatcaaag tttgatataa agacaggtgt tacatctgca aaagttaagt ctatgtcaat
    16861 tagtgttgga gaaaaacttg ttgatatggc taatagtaat gaaaatatag tagcaataac
    16921 agctgcaatg ccatctggta cagggttaaa cctatttgaa agtgcatatc caaaaagata
    16981 ttatgatgtt ggtatagctg aacaacatgc aacaggattt gcagcaggtc ttgcaaaaaa
    17041 tggtatgaaa ccttactttg ctgtgtactc atcatttttg caaagggcat atgaccaagt
    17101 tattcatgat gtatgcataa caaaaaagcc agttactttt cttatagata gagctggatt
    17161 agttggaaat gatggagaaa ctcatcatgg tatgtttgat ttaagttact taaattctat
    17221 tccaaatatt gtagtaatgg ctccaaaaga cacaagagag atggagctta tgatggattt
    17281 gtcattaaaa ttagattgtc cactagcaat tagataccca agaggaagta gttattacct
    17341 agataaggga gagtatggag agattgtact gggtaaatat gaggtattag atgacggtca
    17401 agatacagtc atactttgta ttggaagtat ggtaaaacat gctttagagg ctaaagaaat
    17461 attatcaaga gaaggaataa atccgacaat agttaatgct agattcttaa agccaattga
    17521 tgaaggtatg ttaaaagcat tattaaaaaa tcataaaaat gtagttacta tagaggataa
    17581 tattgtaact ggaggatttg gaagtagaat aaataagttt attatagata atgaatataa
    17641 cgtaaatata cttaatatag caataccaga agaatttgta aaacatggca atatagatga
    17701 attatatgat tttgtaggat tatcgccaaa aagtattgct gataaaataa ggaaattagt
    17761 tattgagtaa aaatctaatg tagatattgt aaattaaaat ttatataaaa tatagaattt
    17821 atcaattaga ataaatatca agtgtgttac ttcaagctac tttagttatc attaaagtag
    17881 cttttaacag aaaggtaatt gtatgaaaaa aagaatagat ttattattag tagaacaagg
    17941 gtactttgaa agtagagaaa gagccaaaaa agcaataatg gctggattgg tttttgttga
    18001 taatcaaagg tgtgataagg ctggtacaga agtaaaagaa gattgtagta tagaagtaaa
    18061 aggaaatcca ataccatatg tcagtagagg tggtttaaaa cttgaaaaag caatgaaaaa
    18121 ctttgatttg actattgatg gaaaggtatg tatggatata ggggcatcca caggtggttt
    18181 tacagattgt atgctcaaaa atagagcaat aaaagtattt tctatagatg ttggttatgg
    18241 tcaacttgca tggaaattga gacaagatga tagggttgtg tgtatggaaa gaaccaatat
    18301 aagaaatgtg acaatagaag atacaaagca gtttgctgat tttgcgtcaa ttgatgtgtc
    18361 ttttatatcg ttaaagttag tacttccaaa ggcaaaggag ttagtacgtc atgatgggga
    18421 agttgtcgct ttaattaaac ctcaatttga agcaggaaga gaaaaagtag gtaaaaaagg
    18481 agtagttaga gaaaaatcta cacatataga agttataaaa atgatttctg atttctcagt
    18541 cgaaaatgga tttgagattt tagggttaga tttttctcct attaaaggtc ctgaaggtaa
    18601 tatagaatat ctaattcatt tgagaaatgg aaatgaagga tatgaatttg atggtgagac
    18661 atacaataac aaaatagtag aagttgttga agcttctcat aatttagaca aataggttaa
    18721 aagggggctt agatttgatc ctcgaattat atatgaaaaa ttgtgcctta gttgaagaac
    18781 taaggttgaa tattgataaa aacttaaata tacttacagg tgaaactggt tcaggaaaat
    18841 ctataataat agatgcactt ggactttgtt taggtgataa atatgatagg tcttttttaa
    18901 gaaaaggaac agataaggga cttgttgagg ctgtattttt ttcagacaat agatatctta
    18961 aaaaaatatt agaagaaaat gatataagta tggaagatga taatttattg gtaataacta
    19021 ggctgatata ctcagatggt aagagtactg ctagagtaaa tggaaggact gttaaagtgt
    19081 ctcttcttaa agaaattgca tctacactta tagatataca tggtcaacat caaaatcaag
    19141 ctttgtttaa taaagatact catttaaaat ttctagacct ttttggagaa aatgaattgg
    19201 aagagtttaa aattgcttat aaaaaggtgt accataagta tagtgaagta aaaaaagctt
    19261 taaattgctt gacagaaaat aaagatgaga tgcaaattca acgagaaata gatttattaa
    19321 gatttcaaat aaatgaaatt gaagctgcaa atctaaataa gaatgaatat gaagatttat
    19381 taaaacaaag agaagtttat agaaatagtg aaaagatata taataatcta aattcgagtt
    19441 atagcaagtt acataatggt gagtataatg ttattgacct aataggtctt gcatctaagg
    19501 aacttaatga catatctaaa tatgacagtg ttttaagtga atatagtgat actgtagaaa
    19561 gaatcatgta tgagttacaa gacatatctg gtgagataag aaattacaaa gataatatag
    19621 actttgaacc ttatgagcta gagcagattg agcttagaat cgacgagatt aataacttaa
    19681 gaagaaaata tggagacagt atagatgata tatttgagta ttatggaaaa attaaagata
    19741 gattagatga aatattaaac agagatgaaa gagttgaaca gttaagaagc aaactgatga
    19801 atatagaaga agatttaaaa ataaaagcca gtaaattgac taaagcaaga atagaagtag
    19861 caactacttt agaaaaaata cttcttgatg aattaaaaag cttaaatatg aaaaatgtaa
    19921 tgttcaaggt taattttgaa aaaggtccat ttactttaga tggagtagat gatattgaat
    19981 ttatgatatc ttttaactta ggagaagata ttaagcctat atataaagtt gcatcaggtg
    20041 gtgagatgtc cagatttatg ttagcgttta aaaccatatt ggctgatata gatgatattg
    20101 atacattagt gtttgacgag atagatactg gaataagtgg gatagcagca cagatagttg
    20161 gtgagaaatt gagtgatata gcaaagaaaa aacagataat atgtataact catttacctc
    20221 aaattgctgc aaatgcagac actcattatt gtatagagaa agatacttca aataatagga
    20281 cgtttaccaa tgttagtaag ttaaatgaat ctcaacgaaa aaatgaaatt gccagactta
    20341 tagcaggtaa caatataaca gaaaaaacta ttgaacatgc aagtgaaatt attgagttgg
    20401 ctaaaaaatg ttagtgaaaa acaagcattt taataggtgt aaagaatttt tatagaaatg
    20461 ctttacacct attttttata atgaaattat tttaaaatat ctagtgccta tattgaagaa
    20521 aagtagattt aaaaatagaa gaaaatttgt ataaatttgt aactttgaaa tttctaaatg
    20581 cttaagtata atattattta ttaaggtagt agtgaggggg acataaaatg aataaaaaag
    20641 atactatgca cttaattttt acaattgtaa tttttatttt attatggtat attgtggtag
    20701 cagtaagtga gattaataaa aatattgaaa gttgtagtaa caaattagat tatttgtcac
    20761 aagagattat gagtactaaa tcggatatta gtaatactat aaatgaagaa atgtcaaaaa
    20821 gttatataac aaagagtatt gacttaaaag taaaaaaaat cgagaaaaaa gagtgtgtta
    20881 ttgatgtaga tgttcaatta agtaaacttg gaaaaaatgg aaaagtattt tttatgtata
    20941 aagaagatag tgataaatgg aatgaaactg agatgacaaa acatggagaa ttatcatatg
    21001 catgtgaaat aaagataaat acaggaagtg aatatgacta taaagtagtt acaagtggag
    21061 ctatatctga aagttctgat gtgcaaaaat tgactaaatc tgattatatg cctgaacaac
    21121 ccatatttaa ttctgggata agagataata gagaatactt tattgaaata gtagaaaata
    21181 gtaatctttt caatcatgag agtgaaaagt caaaaaataa agtttatgat aatattagat
    21241 tagaaaaagt agatattatt gtaaatgaag gaaaaaaaga cactatatac aaagccaaat
    21301 tagctgaagg cttagatgat ggcaaaacta ataattcaaa tagaaatcaa gtgaattatg
    21361 aagtaagttt tcctaaaagg gatattgatg gcataattta tattaaagct aaacttacat
    21421 acaataatgg agtagaatat acaaaggata taactgaaga tataactatg ggattacaag
    21481 atttagaaaa ataaatacat atttaaataa atattcaaat agatttgttc aataaaatag
    21541 agtataaata aaactgtagt agttttactt atactctatt aaaaaattat aattttaatt
    21601 ccatatatct agccccttca attggattat aagtataagg ttctatatca taaaaaccaa
    21661 acttttcgta taatccttgt gcacttttca tgcttggaag agtatctaat ctcatgtgtg
    21721 tatatccaaa ttttttagct tcttcaatga tttcttccaa tagtattttt cctattttta
    21781 atcctctaaa ttgatttctt acatataatc tttttaattc acatatttta ccttcaagtt
    21841 tttttaaagc aacacaacct gccaaatttt catcaacaaa tgccaatatc aatgagcctg
    21901 aaggtttttt atattttcct ggaagtgttt ttaattcatt attaaagtct tgaaaacata
    21961 agtctatatt tagagaattt gaatattcag taaatagaag ttttacgttt tcaaggtttt
    22021 ctaaatcttt ttcttcaaca aattgtaaag ttatattttg agccatttta tccgccatta
    22081 tatacacatg tttatataat gacttcacct ccttgatata tgtatatttt tcttaatatc
    22141 aattagattt taataccatt actttttcac caccatagtc aagctctcca ttaaactcaa
    22201 atccaaaatc tttataaagc ttaatagcca ttttattgtc ttcgaatata ctaagatata
    22261 gttcatcaca gttatattca tttttaagat gatttacaag aaaatctaat gatgcttttc
    22321 catatccttt accttgatat tttgaatcaa tcataaatct atcaagccaa actctatcat
    22381 cttctaaacg accatacata gcaaatccta ttaaagaatt ttcatcatat attccaacag
    22441 gtacccaagc tgttataaat ttagattcag caatagaaag tgcattgctt tctatataat
    22501 ctaactgact tttatctaca gacaaactaa ctaaatcatg ccaattattt atgtctgcaa
    22561 ttcttacatt taatttcaag atattaccgc ccttcaaact ttttgttaca atctaatact
    22621 atcatattat gtattaaaaa tcacttatta agattttaaa taaacttttt aaatgaataa
    22681 attctcagga aaaaggaatt ataaatacat aataatacag cataggagta gatggatata
    22741 tgaacaaaat aaataaaaat ttcaaaaata tttggataat attaggagct gtatcgattt
    22801 ttaccatggt tataattttt aataaaaatt gtaatgttaa taaagagact caaatagaag
    22861 cttttacaat taagaatcat gataaaaaat ttgtatatcc tatgggaaat ataattggag
    22921 taaaagcaaa tacagatggt gtattggtct taggatatga ggaagaggat gtagactata
    22981 ttggaggcat acaaatcggt gataatatag taaaaataga taataaaagg ataaaaaata
    23041 gtcaagatgt atcagagatt ttgaataaga ttaaaaaaag taaagttgaa gtgacttttg
    23101 agagaaaaaa taagtataaa acagaagtaa tagagactaa aaaagaaaat ggcaagtata
    23161 aacttggatt atgggtaaga gataaaatat ctggaattgg aactatgact ttttacgacc
    23221 ctagtatgga aaagttcaaa gcaatcggtc atgccataaa agattcggat actaatgaac
    23281 tattaaagat aaagcaagga tatatatata agccagaaca attaaaaata gtaaaagcta
    23341 gtaatgaaaa agtaggtaaa ataaaaggag attttaatga cagcaattta atgggtaatt
    23401 tctcaaataa ttcagagcta ggtataagtg gtaatattac agaaaaccat aataaagagt
    23461 ttaatgtagc aaataaagaa aagcaattaa tagaagttgg aaggccgcaa gatgtaaaaa
    23521 taggagatgc agtaattctt tttgaggata aaaacaaaaa tataacaagc tatgatataa
    23581 aaatagaaag tatagtatat gataaaggaa attatagaga tatggtaata aaagtagtag
    23641 atgacaagtt attggaatac acaggaggta tcgtacaggg gatgagtgga gctccaataa
    23701 tacaaaataa taaaattatt ggtgcaataa ctcatgtttt tagagataat ccgaaaaaag
    23761 gatatggtat ttttatagat gaaatgataa aattgtaggt gaggcattaa aaaattttat
    23821 tattttatca attatctagg aggaatataa ttttggagtg tcgaatatgc tttagagtag
    23881 ataattagga agcaattgtg taaaaagttt agttttctgt aataagaaga tgttttttaa
    23941 tggggggatt tttagtggaa aaaatcaaaa tagttttagc agatgacaat aaggattttt
    24001 gtcaggtatt aaaagagtat ttgtctaatg aagatgatat cgatatatta ggcatagcta
    24061 aggatggaat tgaagcatta gacttagtaa aaaagacaca accggactta ttaatactag
    24121 atgtaataat gccacatcta gatggattag gtgtaattga aaaattgaat actatggata
    24181 tacctaaaat gccaaaaata atagtactat cagcagtagg tcaagataag ataactcaaa
    24241 gcgcaataaa tctaggagca gattactaca tagtaaagcc atttgatttt gttgtgttta
    24301 taaacagaat tagagagcta gtttctaata gagttacaca agttgagcca aaacctaggc
    24361 cagttcaaga gactcaaatg actagaagtg attttgttaa gaatgtagga aatatagaga
    24421 cagaaatcac aaatataata catgaaatag gagtaccagc tcatataaaa ggatatttat
    24481 atttaagaga agcaataaaa atggttattg ataatgttga gcttttaggt gcagtaacaa
    24541 aagagttata tccaagtata gctaaaaaat tcaatacaac accaagtaga gttgaaagag
    24601 caataagaca tgcaatagag gttgcatgga gtagaggaaa agttgacaca ataaatcaat
    24661 tatttggata tacagtacac aatactaaag gaaaaccaac taattcagaa tttatagcaa
    24721 tgattgctga taaattaaga ctagaacata gtatggttaa ataaacaaga cataaaaagt
    24781 aaggcttttt aattaaggca ttggctataa atgcgtatta caagcagcga aacggtataa
    24841 ccactagggt tataccgttt cgctatttta ataaatataa aaattttctt tattatttgc
    24901 ttactatatc aatataataa ttttattata ctatggatat agtatgtgtc tttacaagtt
    24961 gtaaactgac agtggtttat tttttaatat aaatattgac tttgatgcag gtaaactttg
    25021 tatttttaag cgtattatgg aatatgttaa ataaaaaaat gatgaaatat agtattgtaa
    25081 atgccaaaga tgcaaaacaa acttaaaaca tttattttat tgttaagtaa tgctataata
    25141 taatgtgatt ttaataatga tagtggaggt ttaaatatga gagtcgaggc ccctataaaa
    25201 gtagatcgaa aaaccaaaaa acttgctaaa agagttgaaa gtggggaaat agcagttata
    25261 aatcatatag acatagatga agttgctgca aactctttag tagaagctaa aataaaactt
    25321 gtcataaatg cggctccttc tataagtggt aggtatccca ataaaggtcc agggatatta
    25381 actgaaaata atatactaat aattgataat gttggagaag agttatttga agaattaaaa
    25441 gaaggagaaa ctatagaagt tgtagatgga aagatatata gaaaaggaaa atttttaggt
    25501 gcaggagaag ttttagacaa gtatgaggtt tcacaccaaa taaaggctgc ctatgagaat
    25561 ttagctgtag aattggatag atttatagat aatactatag attatgctaa aaaagaaaaa
    25621 ggatttatac ttggagaagt agaaattcca aaagtgaaaa ctaattatgc taataaacat
    25681 gtattgatag ttgtaagagg tcaggactac aaagaagatt taagtactat gctttcttat
    25741 atagaagagg taaagccagt attggttggt gttgatggag gagcagacgc tttaattgag
    25801 tttggatata ctccagatgt gattgtaggt gatatggata gtgtaagtga tgaagcttta
    25861 aaaaaggcta gtgaaatagt agtacatgct tatacagatg gaagagcacc aggtcttaag
    25921 agggttgagg aattaggctt agatgcagtt gtatttcctg caccaggaac tagtgaagat
    25981 atagctatgc ttatagccta tgagtataag gctgagttaa tagtagcagt tggtacacat
    26041 tcaaatatga ttgattttct tgaaaaagga agaaaaggta tggcaagtac ttttttagtt
    26101 agactaaaaa taggttcaaa gcttatagat gctaaaggtg ttaatttgtt atacagaagt
    26161 aaattaaaaa taaagtacat atgggcatta atagcaacag cattatttcc tgtgttggta
    26221 gttgcatcat tgtcaccagg agttcaacag ttcatacaac taatgcaatt aaagtttaga
    26281 gtattattac agatgtaaat tttaggagga taaatatgca tattaatatg aaatattata
    26341 tagtcactat aggggctata tttatagctt tgggtatagg catgttagta ggatttaatt
    26401 taaataataa tcaacaatta agtgaacaac aagcaaacat aataaatgat ttggatgata
    26461 agtttaatat cttaaaagaa aaaaatgata aacttgacag tgacttagca agtgtaaata
    26521 gagattatga agaggcagtt aattttataa ataaaaatgt agataagatt ttagctggtt
    26581 cgctgaatgg taaaagtata ggaataatat ctgctaatga aaatgacgat tatacaaaaa
    26641 atatagaaga cataataaat aaatctaatg gaagcattgc atttaatata atattaaaag
    26701 aaaacataac aaatccagaa aagttaaagg aaatgtcaac taaactaggt acagatgtaa
    26761 aaaatgcaaa tgatgcagtt aattatataa ttgacactct taaaaaggaa gatgcaagtg
    26821 acattttaac atatcttcaa gaactagatg taataaagtt taattttatt ggagatacat
    26881 atctaaaata tgattccgtt gtaatagctg gtggaaatga tgcaaaagac agtacaaaac
    26941 agtttgaaaa aatagaaaaa tttgtagttt caaaacttaa atcagagaat aaatatttag
    27001 tagaagttca aaatacagga gttaaaactt cttatgtaga actatattct aaaaacaaag
    27061 ttgcaactat agacaatatt gatgaaggta taggaagtat atctctagct attcttctac
    27121 aacaaggtaa tatagttggt aattttggta gattggatac tgcaacttca ttgttgccat
    27181 ctattaaata gaaataattt taaggagaga aaaaatggat tcttatatag gtataataat
    27241 accagcttat aatgaagaaa gtagaataaa atatacatta gaaagcatat tggacattaa
    27301 gcaaataaat gaaataatag ttgtggatga tggttcaatt gacaatactg ctaaggttgt
    27361 atctgagcta gaaaatgaaa agattaaatt ttttaagtta gataaaaata gaggtaaagg
    27421 atatgcttta aattatggta tcaaattagc aatgaaaaat gcagatatta taggttttct
    27481 ggatggagat ttaggaagct ctgctaaaga agttgaaaaa ttaatagtac ctatattaaa
    27541 tggtgaggcg gatgttacaa tagccaagtt tcctcctgca aagagaaaag gaggtttggg
    27601 atttgtaaaa ggtttagcta aaaattctgt gtttgagatg actggtgttg agttagatgc
    27661 aactttgtca ggtcaaagaa tatttaaaag agaagtttta gaaaagtttg atgaaatacc
    27721 ttttggatat ggagtagaag ttggaatgac cattgatata ttaaagtatg gatttaaaat
    27781 taaagaagta ttagtaaata tgactcataa tgaaacagga agaaatttaa aaggttttat
    27841 tcatagaggg aaacagtatt atcacataaa aaaggtttta ggacaaaaaa agaaagaatg
    27901 gaggtaatat cttagtgaaa gattatatac tttataccat tttattatta actggattat
    27961 ttggaaccta tgctgtaatt ccactattta aaaatttatt gataaatgga aatgtactta
    28021 gaccaaacta taaaaaagat atgataccag taagtatggg aattgtattt ttgcctatga
    28081 ttgtaatcaa tggaataata cttgctttct ttactacaga atttaaggat ttagcgtata
    28141 tatttatgtt tatgtttggt atgatatcca tgttttttgc agggatacta gatgatgtca
    28201 ttggaaatag agatgtaagt ggtttaaagg ggcattttaa aagtttattt aaaggaagtc
    28261 ttacaacagg aggttttaaa gctttatttg gtggatttgt agggcttata gtttctgttg
    28321 ctatatcaaa agacataatt gatataatag taaatacact aataatagct ctatcaacta
    28381 atttaatgaa tcttttggat ttaagaccag gaagggcaat aaaagcatat ttattcataa
    28441 tggtaattat atttttaaca ttgacaggat ttgttcaagt tcttccatta cttatagtac
    28501 caaatgtact tgcatacttt aattatgatt taaaagcaag ggctatgatg ggagatactg
    28561 gttcaaacgt ccttggaata tctattggaa tgctcatttc ttttgggtat ccatttaaca
    28621 ttagattagg atggttaata tttgtagtta ttatgcatat attcactgag aaatactcat
    28681 taactaagat aatagaaaaa aataaactat taaattttat agataaattg ggaaggtagt
    28741 attatgataa gcaaaagagt ggggattgtt gaatcaatag taagtcaaac tgaaacacta
    28801 gatgatataa gagtaaatat aaatggagaa atacaaaggg catataatta tcccaaaata
    28861 tctggaacta taaatatagg tgacgaagtg gttttaaata caacagcagt agaactgagc
    28921 ttaggtacag gtggatacca ttttgtaata actaatttaa ataatataga atctacttta
    28981 actgaaggtg gacatataat gaaacttaga tatacgcctc ttcaaataaa agtggattct
    29041 gttgaggaac aagaaagtat ttatcatgat aaatttgcga attttaaagg attagaaggt
    29101 ctttctgttg tagtagggac tcttcatagt atgttaactc catttgcagc ttcatttaaa
    29161 agaaataatc caaataaaaa attagtgtat ataatgactg atggagcatc tcttccaatt
    29221 tatttaagta aaaatgtgga tactttaaaa gaaaaaaaat taatagatag tacaataact
    29281 ataggaaatg cgtttggtgg agattatgaa tgtataaata tatatactgc attaattaca
    29341 gcaaaagaaa tactaaaagc ggatgcagta tttgtcagta tgggacctgg aattgctggg
    29401 acaggaacaa aatatggatt tacagggatt gaacaaggct ctattcttga tgctgtaaaa
    29461 aaacttgaag gaagagcaat tgcaattcca agaattagtt ttgctgacaa acgagaaaga
    29521 catcaaggta tttcacatca tagtatgact gtatttaaag aaattgtaaa tgtaaatgta
    29581 gacataccaa taactatata tgatgatgaa aaattgaact ttataaaaga gcaaatcaat
    29641 ttaaatggtt tagacaaaaa gcataatata atttatatag ataataataa aacgaaagag
    29701 gatttagact attttaatct aaaagtaaag agtatgggaa gaaattatga acaagatgag
    29761 gcatttttca aagctgcaag cacagcagca tattacttaa tggaggttta agatggtatt
    29821 agaagaaaaa actattagta gtgatagggt ttatacaggt aaagtaatta ctttaaaggt
    29881 tgatactgtt gaaattccag ggcaaggata tcaaaaaagg gagttagtag aagttggtgg
    29941 agcagtagga atagttgcaa tcacagatga taataaagtt gtgttagtta agcaatttag
    30001 aaaacctata gaaaagccaa tctttgaaat tccagctggt aaactagaaa aaaatgaaag
    30061 tccaaaagaa tgtgctgaaa gagaattaaa agaagaaaca gggtatagtg caaaaaatat
    30121 taagctaata cataaatttt tcacttcagc aggtttttct aatgagataa tgtttgtata
    30181 tttagcaaca ggtcttactc caggagagaa taatttagat gcagatgagt ttttagatgt
    30241 ctatgaaatt gagcttgaag aagcatataa catggtatta aaaaatgacg ttgaagatgc
    30301 aaaaacatct attggattat tattagtaaa agatatgttt aaaaattaat atttataaaa
    30361 tgaataaccc tttgtcctaa agcatattat tttataaagg acaaggggga attaaattga
    30421 gaagaacata tagaaaaaat gattttagag aattaaatag acaaataatt attataggat
    30481 tgttgtttat gatgtctatt gttgttgggt cttacataaa taaaatattg ccaggttcta
    30541 gtaacaatat attaaacaat ataaatcctg ctgtagagta ttataatcta aatataagca
    30601 taaaagatac agtgatacaa aatttaaaat cagatgcaat ctttatgggc tcaatagctc
    30661 tattaagtct atttgtagta acaattccag cagtgttggt agcttttgta ttaaaaggga
    30721 tgtcaattgg ttatacaata aatagttgta tattggcatt aaaatttaaa agtataaaaa
    30781 tgattttaat aatattattt aaaaatttga ttattattcc atgtgcaatc atattagcat
    30841 taattagttt aagttatttt aaagaaatgg tttatgaatt taaaaagaaa aatagaaaaa
    30901 atatgcaatt tttaattaag aggtatatac taaatattat aattataata gcactatcat
    30961 tggggttgca attaatatta aatactgcaa gtattggtat tattaagttc ctagctaaat
    31021 aaaggagttt ataatggata ttatagaggg atatatagat tacataaaag ataaaaaaaa
    31081 attatcagag aatacagtgg catcatactt tatggatata aaaaaatata tggaatatat
    31141 aaatcaaaaa agcattaaac tagtagatat agtagaaaat gatattataa gttacttaat
    31201 aaagttggaa aaagataatg tatcaatagc tacaatagcg aggatgatat cctctataaa
    31261 atcttttcat gattatttat ttttaaatca tatatgtaca aataatcctg caaaggatat
    31321 aaaaaaacct aaaataaaaa aagaaaatat aaatatactt acagaagaag aaattgaaag
    31381 actattaaat tttccaaagt taacaacacc taaattgatt agggacaagg ctatttttga
    31441 agtattatat ggtactggta taaaagtatc tgaattagta gagatgaata tagaggatat
    31501 tgacctagat attgattata tatattgtaa ttcatgttgt aaaaatcaaa gagtgatacc
    31561 actttgtgat attacaaaac tttacttaga aaagtatcta aaagaagcaa gacctaaaat
    31621 ggctgtagaa ggtgaaaaat cattattcgt aagttcatta ggtcaaaggt ttacacgaca
    31681 aggtctttgg aaagtcataa aaaaatattc taatctagcc aatatagata aaaatataaa
    31741 tcctacaatg cttagacatt catttgctat tcatttgtta aatgaaggtg ctaacattgc
    31801 tgttgtaagt aaaattttag gaaatgttaa tttatctagt ttgcaagtat atttaaatca
    31861 tatagataaa aacgtgagaa gagaaataaa ggagaaacat cctagaaatg atgttgatgt
    31921 agaattacaa aaagcagaag ctaaatagac tatatagcaa attttataat ttagaaggag
    31981 catatttata tgagcagagt aatttggatt gtaattgata gtgttgggat aggagcatta
    32041 cctgatgctg aaaaatttgg tgatagtaag gatgtaagta cccttggaaa tatatttaag
    32101 gaatatccag atattcagat tcctaatatg agaaatttag gtataggaaa catagatggt
    32161 atagattttt ttgaaagtat aaaagaacca ataggttgtt ttggaaagtg taaggaaatg
    32221 tctcagggaa aagatactac tacaggtcat tgggaaatga ctggtataat agttgacaaa
    32281 ccatttaaga catttgaaca tggattctct aaggatataa tagaagagtt tgagaaaaaa
    32341 actggaagaa aagtagtagg aaataaacca gcttcaggaa ctgtaataat agatgagtat
    32401 ggagagcatc aaataaaaac tggagatgta atagtatata catcagctga tagtgtattt
    32461 cagattgctg ctaatgaaga agtaattccc ctagaagaac tctataatat gtgcaaaatc
    32521 gctagggaaa taatgatggg ggataatgca gtagctagag taattgctag accattcata
    32581 ggtaagaaaa aaggtgagtt tgtgaggact tcaaatagaa gagattattc actagaccca
    32641 tttgaaccaa cagttcttga taatataaaa gaatcaggac ttgatgtttt agcagttgga
    32701 aaaatagaag atatttttaa tggaaaagga attacagatg ctatccacac taaaagcaat
    32761 atggatggag tggatgaaac tttaaattat atgaaacaag ataataaagg tctaatatat
    32821 tcaaatctcg ttgattttga ttctaaatat ggtcatagga gagacccaga agggtataag
    32881 aaagctcttg aagagtttga tagtagactt cctgaaataa tggctaatat gagagaagat
    32941 gatattttaa taatcaatgc agaccatgga aatgacccaa catataaagg tacagaccat
    33001 acaagagaat atatacctgt tatgatttat ggcaataaga ttaaaaaagg ttttaattta
    33061 ggagtaaaag atacttttgc tgatattgga gcaactgttg cagatatact aaatgtaaag
    33121 ttgcctaaac atgggtcaag ctttaaagaa gatttatttt aaactataaa atgataaaaa
    33181 cttagcttaa taggatggag agattggaat gtttgaaaag atagcacaaa gtagtaaatt
    33241 tataaattct aaaagtaata taaaacctaa gattggtttg atattaggtt ctggactagg
    33301 tgatttagca aatgatatag aagaccctgt cacaattaaa tatagtgaaa ttccaaactt
    33361 ccctgtatca acagtagcag gacatgctgg acaacttgta attggaaaac ttgaaggaaa
    33421 agaagttatt gctatgcaag gtagatttca ttactatgaa ggatattctc agaaagaagc
    33481 tacttttcca gtaagggtta tgaaagaatt aggagtcgag attcttatag taactaacgc
    33541 tgctggaggc gtaaataaag aatttaaagc aggagatttg atgcttataa gagaccatat
    33601 aaactttagt ggaagtaatc cattagtagg aaaaaatgat gacagatttg gtgctagatt
    33661 tccagatatg tcagatgcat attcttctaa atatgtagat gtagttaaaa actgcgctaa
    33721 agaatgtaat atagatgtca aagaaggcgt ttatatgttt tttagtggtc caaactatga
    33781 aacaccagca gaagtgagaa tggcacaaat tttgggagct gatgctgtag gtatgtctac
    33841 tgttccagaa gtcatagtag cttctcactc taatatagga gttattggta tatcttgtat
    33901 aacaaatatg gctgctggca tcttaaatca accactaagt catgaggaag taatagaaac
    33961 tactcaaaaa gttaaatcag aatttatgaa tttagttaaa acaacggtta aaaatttata
    34021 agttaaagct tattatagat tttttgagga agtttataat aaaatagtta atgtttaatt
    34081 tgaaaagaat taataaaaag ctgtcttgat atagaaagtt atttctaata aaggacagtt
    34141 tttttataat actacaacat ttgaaagtgt tttaaagttt aatatttatt taaattatta
    34201 taggttagaa tggagatttc aattatgaga atgtatgata ttataaaaaa aaagagagat
    34261 aacctagagc ttagtaaaaa agagataaac tactttatag aaaactattc aaagggagat
    34321 atacctgact atcaagcttc tgcactatta atgtcgattt atttaaataa gatgaataaa
    34381 caggaaactg tacatcttac agaagcaatg atgaactctg gagacatgat aaacctatct
    34441 gagatagatg gaataaaggt agataagcat agtactggtg gtgttggaga taagactacc
    34501 atagctctta tacctttggt tgcttcatgt ggagcaccag ttgcaaagat gtcaggtaga
    34561 ggtcttggtc atactggtgg tactattgat aaattggagt ctataccagg tttttcgaca
    34621 gaaatggaga taagtaaatt tattgattct gtaaataagt ctaaaatagc agtttgtggt
    34681 caaagtgcaa aggtagcaat tgcagataag aaaatatatg ctcttagaga tgttacagca
    34741 actgttgata atatatcatt gatatcatca agtgtaatgt ctaaaaagtt agcttcagga
    34801 gctgatgcaa ttgtgctaga tgtaaaaact ggtgatggag catttatgaa gacattagaa
    34861 gagtcttttg agttagctaa atctatggtt gatataggta ctggtatgaa tagagataca
    34921 atagggattg taacagatat ggatgaacct ttaggttttg cagtgggaaa ctctttagaa
    34981 gttatagagg caattgagac attaaaagga aatggaccta aagaccttgt tgagctatgc
    35041 gaagtattag gagcatatat gttggtttta tcaaaggtag cacatgattt tgaagatggt
    35101 gttgaaaaaa taagagaatc aataaaatct ggtactgcta tacaaaaact caaagagttt
    35161 atagagaatc aaggtggtaa taaagatgta gtagatgatt attctttatt caaaaaatca
    35221 aagtataaat atccagttaa atcaactaaa tcaggttata taagcaaaat taaagctgaa
    35281 gatgttggtg tatcggctat gattcttgga gcaggtagag aaactaaaga tgatatttta
    35341 gatttatcag cagggataat tttagaaaag aaagtaggag attatgtaaa tgaaggtgaa
    35401 gttttagctt acatgtatta taatgatgaa caaaagcttt cattggcaaa gggaagattt
    35461 attgattcct actctattgt agattcaaaa atagaaaaaa ataaattaat atatggtatt
    35521 gtaactaaag aagagattaa aaagttttag aaaattttag aaaagtgatt ataaaaggcc
    35581 taacatgtca aaaataatgt taggtttttt attttttgat aaactataaa ttataccaaa
    35641 aatatatatt ttaaaacatt ttttacaata taaataagtt tattctacaa gatgattgaa
    35701 aattaaagta tctagtttta taatagaaaa tggataaata tacataagga gtagattata
    35761 ttatgaactt taaagaaaat agattgaaaa tagcagtatt aataattgtt attttgatta
    35821 tcttagcagg tatatttgtg tttatacaaa taggtcccta tgataaaaat aacaaaaaag
    35881 atgtaattat cgacgttcca agtggagcat ctgttggaaa aatatctgac atattatatg
    35941 aaaataaatt aataaagaat gaactattat ttaaactttt ggtaaaggtt agcaataaag
    36001 ctccgtctat aaaatcagga acatacttac ttaatcaatc gtattcaaac aatgatataa
    36061 taagtctttt agtttcaggt aaaatatatc aggatggtat aaaagtgact attccagagg
    36121 gagctacatc taaagaaatt atagcaatgt tagtaagtaa aaatttagga gataaagcta
    36181 cttttgaaaa tttaataaaa aaacctcaag aattttatga taaatttcta tatttgaagg
    36241 aagatggaat aacctcttta gaagggttct tgtatccaga aacttattat tttaattcaa
    36301 agaaacaatc agaagaagat attttaagcg aaatgttaaa agtatttgac agtaaataca
    36361 cggacaagtt taaaaagaaa caaaaagaat taaatatgac tcttcaagaa gtaatggaaa
    36421 tggcatcaat aattgagaaa gaagctgttc ttgacaaaga cagacctata atagcaagtg
    36481 tgttttataa tagacttaag gtaggtatgc ctcttcaatc agatgctaca atacaatata
    36541 tatttgaaga gagaaagaaa attgtaacat atgatgattt aaaaattgat tcaccatata
    36601 atagttataa aaataaggga ttacctccta caccaatatc aaatcctggt ataaaatcta
    36661 ttgaagcagc attatatcca gagaaaacag actatttata ttttgtagct aagattgacg
    36721 gtggaaataa ttatagtaca aactatcaag accatttaaa atacgttaaa gaatataaag
    36781 aagcaaggga taaacaatca aaagatacaa aagcaacaaa taaagaaaat acaaaaaaat
    36841 aaatcatgat tataaaaagt ctaacagggt aagaataatg ttgggctttt ttattgaaaa
    36901 ttgttattct tagatttata ataaagaaag tgtaaatata tataacaata tgaatttaaa
    36961 aaataataaa ttaatataaa acttgaatat ttattatttt agggagtgtt tttatgagta
    37021 atatagttaa tgatttggtt gaagattata taagagtgac attaaaagaa aaagaaggat
    37081 ttttaaaaga tttagaaatt tatgcagagg aaaatagtgt tcctataata cataaagaag
    37141 tttcagattt attaaaagtc ttgttaaagg ttcaaaaacc aaagagaatt ttagaagtag
    37201 gatgtgcaat tggttattct tctatttttt ttgcaactat tataggaaaa gatgcagata
    37261 taataactgt tgagagaaat gaaaaaatga tagaaaaagc aaaagaaaac ataaaattag
    37321 ctggatttga caataacata actatactag aaggagatgc agaagaaaaa cttagtcaag
    37381 tccaaggtga atttgacctt atatttatag atgcagccaa aggtcaatat aagctatttt
    37441 ttgatttagt tatagataaa ttaaaagatg ggggactttt agtatctgat aatattttgt
    37501 ataaaggtat ggttgctcat gatgattttg ttgtaagaag aaaaaagact atagttaaaa
    37561 gaatgagaaa ttatttagat tatatatgta attgtgacta tttaagcaca tcattggtac
    37621 caataggtga tggtgtagca ctaagttata aagaaagtaa aagaggtgat gtagatggaa
    37681 ttaaataaag tagaactttt agctccagca ggtgatttgg agagattgaa aatagctata
    37741 acatatggag cagatgccgt ttatataggt ggagaaattt ttggaatgag gtctgcagcg
    37801 aagaatttta gtaaggaaga tatggcagag ggagtagctt ttgcacatga aagaggcaag
    37861 aaagtattcg taacagtaaa tataatacct cataatgaag attttctaca attagaagac
    37921 tatttgttgg aactagaaga gataggaata gatgcagtta taatagctga cccaggagtg
    37981 cttagtgtca ttaaaaaagt aattccgaat atggaaatac atttaagtac acaagcaaat
    38041 acaaccaatt atctaagtgc aaacttctgg tacgagcatg gaataaaaag agttgtagtg
    38101 gcaagagaat tatcttttga tgaaatatct gagataagag caaaaacacc tttagatatg
    38161 gatatagaag cgtttatgca tggtgctatg tgtatttctt attctggcag atgtttaata
    38221 agcaactata tgactggaag agatgcaaac aaaggttctt gtgctcaatc ttgtagatgg
    38281 caatatcatt tggtggaaga aaaaagacct ggtgagtatt ttccaatata cgaagatgaa
    38341 aggggtacat tcttctttaa ctcaaaagat ttatgtatga tagagtatat accagagtta
    38401 atcaaatctg gtataacaag tttaaaaata gaaggtagaa tgaagactgc atactatgta
    38461 gctactgttg taagagcata cagaatggca atagatgaat tttacagaga cccagaaaac
    38521 tggaagttca atccaatgtg gatggaagaa ctaaaaaaag gtagtcatag acattttaca
    38581 tcaggttttt acttgaataa accaacaaca gaagaccaaa attatcaatc agcatcatat
    38641 gttagaaact atgattttat aggtatagtt agagaaacag aagatgaaga tggtcttatt
    38701 attgttgagc aaagaaataa aatgtgtgtt ggtgatgaaa tagaagttat gggaccatat
    38761 aaagaaacta tgtttactaa aattgaagaa atgtacaatg aagaaggaga agctatagaa
    38821 tcagctcctc atcctagaca aatagtgaag ttaaagctat cagtaaaagt tggtaaagat
    38881 tatatgctta gaaaagttat agaagaaaag gttgaagaat aataaaaaat tgataaaaat
    38941 agtattagcc ccttagaaat tgtcaataat gaaattatct aaggggtgat ttcatgtcaa
    39001 aaaagaagac tccatttttg aaaaaagtgg gaaagagaag ctggtgtata tttactataa
    39061 ttttaataat ttatagtgtt ttaatttata ggctagttga tatacaagta ttaaaaggtg
    39121 ataaatacaa acaaagtgtt gaatcacaaa gcgttgagaa agttgagtta aatagtggaa
    39181 gaggaataat ctatgataga aacaacaaga agcttacaga tacaagtaaa tctcaggtat
    39241 taattgttga aaaagaaaaa ttaaataata actataaaat tttggagctt attaagaaag
    39301 ctactaagat gaatgattta gatatatata aagctgtaca agagcaattg acacgcccta
    39361 taatacagat tcagactaaa aatatcgata agagtatgaa aaaagaactt gagaaaaatg
    39421 gaataatggt agaagaaaaa actatgaggt acgcaaaaga tggtttatta tcacatacaa
    39481 taggatatat aaaagaagat gataaatcag gtcaatcagg aattgaaaag agtatggata
    39541 gtgtacttag aaattcaaat gaaaagtata taagtgcttt taaagctgga gatgcaggaa
    39601 atgaaaaatc tctaaacata ctaaagggaa gtgtaaaaac tgttgataat aaggataaag
    39661 atagacatct aaaaactact attgattata acattcaaaa aaaattagaa caaatactaa
    39721 ataaagaaga aaatcctaca gcagcaataa tctcggaagc atctacaggt gaaattcttg
    39781 caatgtgctc tagacctaat tttgaccaaa atgacatatc aaaaagttta aaaggaaaaa
    39841 atggggaatt tgaaaataga gttataaaag cgacatatcc accagggtct gtatttaaga
    39901 tggtagtttt attttctgca cttgaaaatg gtgttataga tgagaactat acttacaact
    39961 gtacaggtaa gactaaagtt gggaatacta atgaaatact gcgatgtaat aaaagagatg
    40021 gtcatggttt ccaaaactta agacaagctt tttctaattc atgcaatcct gcatttttag
    40081 atatagctat gaaacttgga aaagaaaaga tactcaaatc tgctgaaaaa ttacatttat
    40141 ttgaaaaggt tgatattggt cttgatgaag aaaaaattag agaagctcca aaaaacatat
    40201 caataagaaa tttagctata ggtcaagaaa atatagaatt tacaccactt caaataaatc
    40261 aaatgactca aataatagct aataatggaa cattcaaacc actatactta tataaaagtc
    40321 ttgtggacaa taatatgaat acaataaaaa cttataagtc ttcaaaaaaa gaagaactta
    40381 tttctcctta tgtgtgtaca caagttaaag aatatatgaa gtctgtatct aggattggta
    40441 cagctaaaga cctaaaagat attgaaggtg gttgtggagt taaaactggt acagctcaaa
    40501 gtagtttaaa taaaaaagct atagaccacg gatggataac aggattttat cctgaagaaa
    40561 gacctaagta tgtaataact gtgttagtag aaggaactca aaaaggaaat aaatctgcaa
    40621 cacctatatt taaggaaata tgtgaaagta taaaataaat tatgtactat aaaatttaag
    40681 gatatatcgt aactttgatt ttagatagaa aactttgtct aatgatgtac gatatatcct
    40741 tttaaaatat agtattaact ttcttgaaca agctcttttt ctagtttttt aagagctttt
    40801 ttttcgattc tagatacata tgaccttgat atatcgagtt tttgtgcaat ttctctttgt
    40861 gtcttatagc cataaggagt taacccatat cttaactgga caatttctct ttctctagga
    40921 gtaagaattt tgtttagttg ttcgtaaagt tttccaactt gaacttttag ttcaacttca
    40981 tcaagaacat agttagcctc tgtaccaagt atatctaaaa gacttatttc attaccttct
    41041 ttatctgttc cgatagggtc ttgtagagat acttgagttt tatttttttt gttagatcta
    41101 atattcatta aaatctcatt ttcaatacat ctagaagcat atgttgctaa tcgagttcct
    41161 ttatctatgt tataagtttc tatagcttta attaatccta ttgtacctat ggatattaaa
    41221 tcatcctgat cttccgttga attattatat ttctttgcta tataagctac taatctcatg
    41281 tttctttcaa ttaatgtatc ttttgcactt ttatcgtttt ctattttaaa tttagttaaa
    41341 tactcaatct cttcttcagg ggttaagggt ttttcaaaag atttaagagc tgccaatagg
    41401 tcaccccctt ttcaacggtc actttaaatt atatgaagga gacttatcca agttgactgt
    41461 tatctaataa aataatatgc atatttttag aatttaaaac atatatttgc aaacttttga
    41521 atggaatatg acataaagag tgggaattta aatttaagtt tttgttgtat atatatgaaa
    41581 caaggcgaag aaattattga tttataaagt ataaattgga attgaggtgt caataaatat
    41641 aaaaggaaat agtatttata tatgttttgg tgttgaagta aaagattaat gcaaagtatt
    41701 agagtctata aaaatatgaa tataggaggt gtaattttac aatatttaaa aaagtaaatg
    41761 taattaattg tttgtataaa attgattaca agcaaaagta tcagtcatag ttaatactgt
    41821 taaggatgaa ggtggtgtgt taatttatat atgtatggga agaaattttg attacaatga
    41881 aaaaacttac aaaagatatt tacgaaaaaa cttatagtta aatgtttata tataaaatat
    41941 tatttagggg ttgtttttat tattgaaaat aagaaagagt ggttttatat caatcgaatg
    42001 tataataagt attgctatat tatatgtggc tgtttattta gtttctacat cattgtataa
    42061 ttgttatagt tttatcagta gaaatatatc tgacagagaa atgttaagta cagcaaaaaa
    42121 atatatagaa gatgagaagt atagaataca aaatagtaag tatgagttaa ttgaagataa
    42181 gatagaaaaa aattacataa atggatatga aattaacagt agaatagagc aaattttaga
    42241 ttattatcaa tgctatgaaa taaatataga gataaaaaat gaatttaaaa aactgaggtt
    42301 taatagctat gttactagaa aataaaggct ctatattaat aataacattg ataatatttt
    42361 ctattataag tactgtgtgc attatgtgta taggtttaat ttatacacat aataatatgt
    42421 ttgagttagg atacaaggac attcaactaa aagaaatttc tttaagtgga atagaaatat
    42481 cagtaagtaa tgtactttct tgtgttgagg aagctattga tgtatctaat aatgaagacg
    42541 aatttagaga atatttctta ggaaataata tgattgaatg tataaaaaaa ataaaagata
    42601 catcttatag tagtttagaa gaactttctt taaaagtaga aaataatact atttatgaca
    42661 gaggagattt ttttgaattt gatatagaaa gtaatgttag agaaaaagaa tttttaaaag
    42721 caataaaagt aagagtgaaa atcaaaaatc catggatagg aattgacatt gaagattata
    42781 tggataaatc taataacaat aaaattgatg acaaaacatt caataattat aaagcatctg
    42841 aaaataatga aattctaaat caatttaaaa atgaaagtga aaatataagg aatcaagagg
    42901 ttggtggatt tacagaagaa gatgaagaat atgaagaaga acttaaacaa aacataattg
    42961 aaaatataaa gaagaatttt gatgaaaaaa acctagtaca ggtatataag tataggggtg
    43021 tataactttg aaaaaagaag gaatgtgact gtaatagaat taatagtatc tatcagtata
    43081 atactcttga tagttacatt atcttttcca aaagataatc ttgaaaatca taaaataaat
    43141 ttatttgcac gtcaactttg ttcagatata aggtatgtta ggcgaattaa tatgtttagc
    43201 aactacaata catatatata ttatataaat caaggtaaac acgaaggtta tgtattgaga
    43261 aaagatggta aaaacattaa atcaataatg ctacctaaaa atgcaaaaat agctaggagt
    43321 attgaaataa taaagtttaa atctgatggg tcgcctcaaa aggcgtctac aatagagata
    43381 tataataata gattaagaaa aactataaca ataacacctg taagtggaag agtacttctg
    43441 aaagagggaa aatatgaaac ataaatatgg ttacttgctt ttggaaagtg tcgtatcatt
    43501 gtcttcaatg gtgataatta tactagtttt atattctata tttttgtcta caataaactt
    43561 aaagttaaaa gtagaagata agatagaact acaacaacaa agtcttgaaa tcataaaatc
    43621 tatggaagga attattagca attctatggg aataatgaat gtatctaatt atgaagaaac
    43681 atttaaaaag acaacatcta taaaatgtag atatttagat gaaaataata atgaagaagg
    43741 cataagtaat aaagaaatta tattgaatga aagacgaaat aagttatttg taaattcttt
    43801 aaatggcgaa agtagtcaag caggtggtta tgaaattgga gattatgtag atgagatgta
    43861 tgtatcaatt actaataatg gtcaatatgt taatattaaa ttgaaattat caaaacgtag
    43921 tcaaaaatat gagactgatt tcaaaataaa agtatggaat tttagtgaaa gtatataaaa
    43981 atacataaat ttaagagaaa gaagtgacat caataagtca tataaaatat aattattgag
    44041 aactatataa ctaaataata tcaatatgta aagtgtatag attaagaata tagaggataa
    44101 taataaaaat atagaataag taatttgcca aatacttgtt tatattgtat aacttatgat
    44161 attatgatat tagtaaaaat ttgtaatcct gacttgacag aattcaagta agagatataa
    44221 ttttaaaggc atagtaatgt aaaatttact aaaaaataag aaatttattt taatatggag
    44281 gaacaaaaaa tggtatcagc aggtgatttt agaaaaggtg ttacatttga aaaagatgga
    44341 caaccatgtt tagtagttga ttttcaacac gttaagccag gtaaaggagc tgctttcgtt
    44401 agaactaaat acaaaaactt aaaaacagga gctataagag aagaaagttt caatccaagt
    44461 gaaaaattcc ctaaagctgt tatagataca agacaaatgc aatatctata caatgatggt
    44521 gagttatatt attttatgga tcaagaaaat tttgaacaaa taccattaaa ctatgagcaa
    44581 gttgaagatg caattaagtt cttaaaagaa aatgaagttg ctacaataag attttaccaa
    44641 ggacaaccat tccaagtgga agcgccaaac tttgcagagc tagaagttac agatacagag
    44701 ccaggtataa aaggtgatac agcaagtaat gtaactaaag cagctacagt tgaaactgga
    44761 gcagttgttc aagttccatt atttataaat actggagata aagtaaagat agatactaga
    44821 acaggtgaat atttatcaag agtataaaaa tttatgtata taaaagctta tatgtcttaa
    44881 taatataaga tatatgagct tttagtttat atataaaaaa gaaagcgagg ggtgttacat
    44941 gaaacattta tatgaagaag ttgcatactt aaaaggccta gcagaaggac tagaaataag
    45001 tgctgaaagt aaagaaggga aaatgataca taaaatagtt gatgcattag aagtatttgc
    45061 agatgctatt gtaacattgg atgaagaaca agaagaactt caagattttg ttgaatctat
    45121 agatgaagat ttagcagatt tagaagaaga tattgctgac atggaagaag atctttatga
    45181 agaagatgac gatgaggatg atgaggactt cagctatata gaaatggaat gcccaaattg
    45241 tggagagtta gtagaaatag acgaagattt gttatatgat gatgaagtag atgttgtttg
    45301 tcctgattgt aaggctgtga tattatcatc agaagatgat tgtgatgatg attgtacatg
    45361 tggtggttgt tcaagttgtg atgatagaga gtaaaaattc ataagaatta aaactgccta
    45421 tgatgcctat gagatatttt gcttcatagg tagttttatt tttatgagga agggtattat
    45481 gtattttggt tttgcaatac ttggacaaaa atagtacact agaatttata gaataggatt
    45541 ttggagggat gtaaatatga aaataagtaa aaaattacta gataatatac aaagatttga
    45601 aaatgttata aattataaat ttaaaaataa agaatatata ctagaagctc ttactcatag
    45661 ttcatattct aatgaaaata aaaaatataa ttttaacgaa agattggaat ttttagggga
    45721 ttcggtttta ggcatagtga taagtgatta tttatttaat gaagaagcta atctgcccga
    45781 aggggaacta actaaactta gagcaaatat agtttgtgaa gattcattaa gtgaagtagc
    45841 taatgatata aatttaggta ttcacatgtt attaggtaga ggagaagaag caacaggagg
    45901 aagacatagg acttcaatat tagcagacgc atttgaagct gtaatagctg ctatatatct
    45961 tgatggaggt tttgaaagtg caagacagtt tatacttcat catatggaaa atataattta
    46021 tgattcaaga aaaggaaata tatttagaga ctacaaaacg catcttcaag aggtgttaca
    46081 agggaatgga gaaaataata tctggtacag gcttatagaa gaaaaaggac cagaccataa
    46141 taaaagattt gtaatggaag ttggaattaa tgacgatgta cttggtatag gagaaggcaa
    46201 gagtaaaaaa gaagctgaac agttagctgc taaaatagct ttaaagaaaa aattatggga
    46261 aaaataaata taatatgtaa aaatataaaa agaaatattt atattagaag gatgttgtag
    46321 atgaaaaaga gaattatacc tatatttgtt cctcacaaag gatgtcctca tgattgcata
    46381 ttttgtaatc aaaaaaaaat aacaggtgtg agtactgatg ttactagtga agatgcaaga
    46441 aatataattg aggaatgttt agagactata gataaagatg cagatgtaga aatagcattt
    46501 tttggtggta gctttactgc tatagatatt gatatacaaa aaagtttatt atcagttgct
    46561 aaagaatatg tagaaaaagg tcttgtaaaa gatattagaa tgtctacaag accagattgt
    46621 attgatgaag atatattaag tatgttaaaa gaatataaga caagtataat tgaactagga
    46681 gtacaatcct tagatgaaaa agtattatta gatagtataa gaggtcatca atctgaaatt
    46741 gtatacaaga gttcaaagat gataaaaaat agtggaatca aactcggatt acagatgatg
    46801 attggtcttc cagctgacac agaagaaaag tgtatattta cagcaaaaaa atttgtagag
    46861 ctaaaaccag attgtgttag agtctatcca actttggtag taaaagatac aggtcttgaa
    46921 aagttaatgg aacaaaataa atataatcca tttactcttg aagagagtgt aaatatagta
    46981 aaaaaagttc ttgtactgtt ttatgttaat aatatcaatg taataagagt tgggcttcaa
    47041 gctactgatg atatacaaat tggaaaagct gttttagcag gaccatatca tcctgcattt
    47101 agagagttgg tagaagcaga tatgataaaa gattatttag aatttgttat tttgcaaaat
    47161 aaaaatataa agcaaatgtt ggtcaaatct aataaaaaga atatttctaa aatcatagga
    47221 aataaaaaaa caaatgttaa atatatggaa gaaaaatttg gtgtgctttt aaaaacacaa
    47281 gaatcagatt tagatataaa tcaattagaa attgtgttag atgggaaaag tttaattagt
    47341 gctaatatga gagacattca tagaaaattg tatgacattt atgaccttta gttttaataa
    47401 tgaagggaga gaaaagattt gtatttaaaa agactagagt taaagggatt taaatccttt
    47461 ccagtaaaaa cagatattat ttttaaagaa ggaataacag ccatagtagg accaaatggg
    47521 agtggaaaaa gtaatatatc tgatgctgta agatgggtat taggagaaca gagtattaag
    47581 agtcttagag gtgataaact cgaagatgta atatttgcag gtacagatac aaaaaaacct
    47641 atgaattatt gtgaagtggc tcttactatt gataattctg aaaatcaatt ggaattagat
    47701 tttacagaag taactataag aagaagggct tatagaaatg gtgaaagtga attttttcta
    47761 aataataaaa gttgtagatt aaaagatata aaagaagtct ttttagatac tggtattgga
    47821 aaagatggtt attcaatcat agaacaagga aaagtagatg aaatattaag taataatcct
    47881 ttaagcagaa gaaaagtttt tgatgaagct tgtggcatat caaaatatag atataaaaaa
    47941 caggaagcag aaaggaattt aagtaataca aaggaaaatt tagaaagaat agatgatgta
    48001 tatatagaaa ttgaaaatca attaaagcct ctttttaatc aacagacaaa ggcaaaaaag
    48061 tacttggaaa taagtgaaaa attaaagaca cttgaagtaa atagctttat aagagaaatt
    48121 gaaggaatag aaaaagaatt aagtgaggtt aatgaacatc gtaaggttat tgaaaaggag
    48181 ctcaatgaaa aagaagaaca aaaaaatgtt gtagagaaaa agcaagaaga tattaataaa
    48241 gaggtagagg tattacaaga tgtaattgaa aaatctgtag attatataaa ttcaattaaa
    48301 ggagttatat caaaaaaaga atcccaaata aatttaatta aggaaagaat aagaaatttt
    48361 acgaatgaaa ttagtagaaa aaatttagaa ataaaggata taaaagagaa gctaaatgaa
    48421 aataagcaat acataaaaga attagaaagc aataaattat caggtagtga agaactatct
    48481 accttgcagg aaaatataaa agtattggaa tcaagtaaag ataaacaaaa aattaagtta
    48541 gaatccctaa ataatgagat agaattattg aaagaaagta taattgatat attaaataag
    48601 aaacaagagt ttagtaataa gctgtccact ttaaacgcaa ataaagaaaa tatgaatatc
    48661 agagatgaaa atataaattc agagataaca gagttaaaca aaaatattga aataaaatca
    48721 tctgaattag atactataaa taaagaattt aatatgcaaa atgaaaattt aaagaatgta
    48781 aataatagac ataaagaatt atcaattaat ttgcaggatt caattagtga acacaataaa
    48841 ctagaagatg aaatacagaa aagtaaatat aatttaaatg gatataattc aaagttaaat
    48901 gtctatatag atatggaaaa tcattatgaa ggatttaata gaggagtaaa agaagtacta
    48961 aaaaataaaa atttaaaagg agttcatgga gcattaggac agattataaa tgtacctgaa
    49021 aagtatgaga aatctataga agcagctctt ggtgcttata tgcaaaatat aataactgat
    49081 aatgagttta gtgctaagtc tgcaataaac tatctaaaac agaataattt aggtagagta
    49141 acatttcttc cattaaatat aattaaatca aataaaataa gtctaggaaa tttaaaagca
    49201 aatactaagt tcataggaat agcaagtgat ttaattacat ttgatgaaaa gtatagaaat
    49261 ataattgaaa atatacttgg aagaacaata cttataaata atatagatga gggcataaaa
    49321 tttgcaaaag aaactggtca taggtttaaa atagtaactt tagatggtga aatcttaaat
    49381 ccaggaggtt ctttgactgg gggaagtcta aaaactaatg ggaatatact atcgagaaaa
    49441 agatacatta atgaatatac agaaaagata agtaatatca agaatgaaat ttcacatcta
    49501 gaattaaaaa gagaatcttt agacaaagat gtgaaaaata taaaaaatga aattgattca
    49561 catgaaagta aaataaaaga tttagaaaaa agtataataa taaaaagtac aagtataaag
    49621 aatgttgagt ctgaaattga atcgttaaaa ggtagtatta ctaaattaga aaatgagaag
    49681 aatgatttaa attctaacct aaattataca cttgaaaaaa gtgatgatgt tagaaaagat
    49741 atggaagagt tagatgattt atacaataaa aataaagaaa aaattgatgc attgaatgag
    49801 gaaataaaaa gatacaatga tttatatgat aaagaaaaat ctgaatttga tgaattgaac
    49861 ttaagtttag tgaagaaaac agaagtttac aatagtatag ttagagatat aaaaagaata
    49921 tctggtgaaa attgtgagtt agaagaaaaa aataaacaat tagaagagtc attaaattat
    49981 gaagaacatg aaataattaa attacaagat tctatactca ctgaagaaaa agaaaaagaa
    50041 aatttaacaa aacaactagg ggatagtaat agaaatcttg aaactagaaa aatagcaaaa
    50101 gatgatttaa aaaatagttt tgatgaaatt aataaagaat taaaaactat agatagacag
    50161 catatagaac ttaaagaaag tttatttaaa gttggtggaa gattagaaag attaaaaact
    50221 agtcaagaca catatataaa taagttgttt gagcaatatg atatgacctt agtacaagca
    50281 ttggaaatta aagatgaaga tttggatata gatagaaaat tcttagaaag tctaaagaga
    50341 gaaataagaa gtcttggaaa tataaatata gactctataa aggaatatga ggaaataaaa
    50401 gaaagatacg atttttatag cgaacaaaag caagatttag aagagtctat ggaagagata
    50461 gaaaaactta tacatacttt agaagaaaat atgaaatctg aatttgaaat taagtttgaa
    50521 gaaataagta aaaattttaa atatgtatat aagagattat ttggtggagg ttgtggagaa
    50581 ttaactattt tagataaaga aaatttatta gaaagtgata tactaataac agctcaaccc
    50641 ccaggtaaaa aaatgaaaaa tttaaaccta ttatctggtg gagagaaagc tttaacggca
    50701 ataagtatat tatttgctat attgattaca aagccaacac cattttgtat attagatgag
    50761 attgaagcgc cacttgatga cgcaaatata tttagatttg gagaattttt gaaggattta
    50821 tctaaagaga ctcaatttat atcagtaact cataggagag gaacaatgga agctgctgat
    50881 tatatctacg gagttacaat gcaagaaaaa gccatttcaa aagttattag tttaaaatta
    50941 aaagaagctc aggaaataac agatattata taacttagat tgacatagga ggaataacag
    51001 tgttaaaaaa attatttggt tttggaaaag acaaggaaaa ggaaatagaa aaaaaagatg
    51061 ctgaagaaga aatagaagtt gaagacagtg ttgataattt agaaaacttg gaagaaacta
    51121 ttttttcagg acttgaagaa gaagtgatag ataaagtgga agatgttgaa gaaaaaaatg
    51181 aggaaagtgt caataatgaa ggcactgaag aaatcgaaaa ctttgaaaaa atagaagttg
    51241 agatgaatag taatggaaaa gaagtagaaa atatttcaaa taatgattct caagaagaga
    51301 taatcgaaga attagaaaat tatgatgaaa ttgagtctaa agagatagaa gataaagaag
    51361 ataagaaagt taacttgttt gaaagactaa aacaaggatt gacaaaagca aagcaaggaa
    51421 taactgatag aatagatgaa gttttaaaat catatacaaa gatagatgaa gaattacttg
    51481 aagatttaga ggaaatttta ataacagcag atgttggtgt aaatacaact atggatataa
    51541 ttgaaagact aagagataaa ataaagcaaa aaggtattac tgaaccaata aaggtaagag
    51601 aagaacttaa atctatagtt gaagatattc ttacaaatga aaactctaca ctagatatag
    51661 aaccagcacc atgtataata ttaatggtgg gtgtaaatgg ggtcggtaag actactacaa
    51721 taggtaaact agcaaataga tacaaaaaag atggtaaaaa agttttatta gcagcagcag
    51781 atacatttag agcagcagcg acagagcaat tagaaatttg ggcaaataga accaatgtag
    51841 acataataaa acatcaagag ggagcagacc ctggagctgt agtatttgat gctataaaag
    51901 ctgcaaaagc tagaaaaaca gatgtattaa tatgtgatac agcaggaaga ttacacaata
    51961 aggctaatct tatgaatgaa cttggaaaag tatttaaaat agtagataga gaatttccag
    52021 aagcaaaacg tgaagtactt cttgtggtgg atgctacaac aggtcaaaat gcagttgttc
    52081 aagcaaagac atttaaagaa gttgcagata taacaggtat agtacttaca aaacttgatg
    52141 gaactgcaaa aggtggagta gtccttgcgg taaaatcaga agtagatgta cctgtaaaac
    52201 ttattggagt tggagaaagt gtagaagacc tacaagattt caatgcaaaa tcattttcag
    52261 atgcattatt tggtaactaa tgttctttta aaaataatgg ttgacaagag tgttgttatg
    52321 atataaaata caatagtgta aagtaaataa cctttacagt atactgctag gaagtgtaag
    52381 atatgaatat agaaaaaatg gtcgaaattg gattgttatt tgaacagtat aaagaattat
    52441 taactgacaa gcagaaagaa atagttgctc tatactatga agaagattat tctttaggtg
    52501 aaattagtga aaatctgaat gtatcaagac aaggtgttta tgatacctta aagcgttcag
    52561 aaaaaatact aagagattat gaagaaaagt tacacttagt atcaaagatt caagagcagg
    52621 aaaaaaatat taagattata aaagataaaa ttattgacat taaagaagat ttattgcaca
    52681 atagagattg tgctaattta atccctaagc tagaaaatat agaagatgta tgtagggaga
    52741 tgataaaatg atatttgaag gattgtctga taaactacaa ggggcattta gtaagttaaa
    52801 atctaaagga aaacttacag aagtagatgt aaaaaatgct atgagagaag ttaaacttgc
    52861 tcttcttgag gcagatgtta actttaaagt agttaaagat ttcataaaaa aagttcaaga
    52921 gagatgtgtt gggcaagaag ttatgcaaag cttaactcca gctcagcatg taatcaaaat
    52981 tgtaaatgaa gagcttacaa gtttaatggg agatgtacaa agtaaagtaa tgatttcctc
    53041 aaagcctcct acaattttaa tgatggttgg attgcaaggt gcaggtaaga ctactacagc
    53101 aggaaaactt ggaggatatt ttaaaaagca aggtaaaaaa cctctattag tagcttgtga
    53161 tatttataga ccagcagcta taaagcaact tcaagttgtt ggagaaaaat tggatatacc
    53221 tgtattcaat atgggagata aagaaaatcc agtaaatatt gcgaaagcag gtttaagcca
    53281 tgcgattaaa aatgctaatg atttagttat tatagataca gctggtagac ttcatataga
    53341 tgaagtactt atggatgagt taaagtctat taaatcagaa gttaagccac atgagatact
    53401 tttggttgta gattctatga caggtcaaga tgctgtaaat gttgcagaaa gcttcaatga
    53461 ggcacttggt gttgatggag tagtattaac taaattggat ggagatacta gaggtggtgc
    53521 tgcactttca ataagagcag ttacacaaaa gcctataaaa tttatgggga tgggagaaaa
    53581 gctagatgat atagaacctt tccacccaga tagaatggca tcaagaatat taggtatggg
    53641 agatgtctta agtttaatag aaaaagcaca agaaaatata gacttagaga aagctaaaga
    53701 attagagcaa aaaattaaaa aacaagagct tgattttgaa gatttcttac aacaaatgga
    53761 acaaatacaa aatatgggac ctcttgacaa gatacttggt atgatacctg gtatgggaaa
    53821 tgtaaaagac caacttggag atgtagattt gaatggcaaa gaaatgaaga gaacaaaagc
    53881 cataattcag tcaatgacta catatgagag aagaaaccca ggagtattaa atgcttcaag
    53941 aaagaaaaga atagctaaag gcagtggaac tagtgtacaa gatgtaaata gacttataaa
    54001 acaacttaat gaaatgaaaa aaatgatgaa gatgtttgct ggttcacaaa agagtatgaa
    54061 gaaaaggggc ggcttaggcg gtttaccttt ttttaaataa aatataaaaa agtaaaaatt
    54121 attcggaggt gactgtaatg gcagttaaaa taagattaaa aagaatggga gctaacaaaa
    54181 aacctttcta cagaatagta gtagctgatt caagagctcc aagagatgga aaatttatag
    54241 aagaaatagg atactataat ccaatttctg aacctaaaca agtaagaata aatgatgaaa
    54301 aagctataaa atggttagct actggtgctc agccaacaga agtagttaaa aaattacttg
    54361 taaaaaacgg agtaatagaa aaattcgaag cttctaaaca agcaaaataa ttttttcttg
    54421 gcaattagtt taagtaaggg ctcattgcta aggttacttt aggagatgaa atatatgaaa
    54481 gagctagttg tagatatagc taaggctcta gttgataatc ctgactcagt tgttgttgag
    54541 gaatttgaag ataatgatgg tatcatctta aagcttacag ttgctcaaga ggatatgggt
    54601 aaggttattg ggaagcaggg aagaatagct aaagctataa gaactgtcgt aagatctgtt
    54661 gcaaatagag aaaatataaa agtttctctt gagatagtat aaaataggag gattaggtat
    54721 aatgcctagt cctttttata taaatgcgta gtttaagatt ttatgatgat atgaccacat
    54781 aagattaaat tttttaagaa ggtgataaca tgaaagaaaa attaactcat tttaaggtag
    54841 gtcaaatagt aaatacacaa ggtttaaaag gtgaagtaag agtttatccg cttactgatg
    54901 atatagagag gtttgatgaa ttaaaagatt tctatctggg aaaagattta aataataaat
    54961 tggctgttga aaaagtaaga tacaaaggtt ctatggttat aatgaagata aaaggcatag
    55021 acagcataga gaaagcagaa aaactaaaaa ataaatttat gtatgtatct agagaagata
    55081 gcagagagct tgaagaaggc gaatttttta tagcagatat gattggaatg gaagttttaa
    55141 ctgtagatgg aaaatatgta gggatactag aagatgttct tcaatactca gcaaatgatg
    55201 tctatgtagt aaaaggtgag gaagataaag aatttatgat accagctata aaaaaatttg
    55261 tacctacaat agatattgat gaaagaaaaa tgattataga ccctattaag ggaatgatag
    55321 attaggtggt aatatgagat ttcatataat gacacttttt ccagaaatat ttaattcgta
    55381 catggatgaa agtataatga agagagcagt tgaaaaaggt ataattgagg ttcatatata
    55441 taatataaga gatttttcta ataataaaca taaaaaagta gatgattatc catttggagg
    55501 aggagcgggg atggtaatga ctcctcaacc tatatatgac acatataagt atataataac
    55561 aactcataat ataaataacc caagtgtaat ttatcttact ccaaaaggta aggtatacaa
    55621 tcaatctatg gcaaagcaga tgtctttaaa agaagatata atactactat gtggtcatta
    55681 tgaaggaata gatgagagaa tcattgattt aatagttact gatgaaattt caattggaga
    55741 ttatatatta actgggggag agctcccagc acttataatg atagattcta tatcgagatt
    55801 aataccaggt gtattaaacc aagaagaatc atttgaagaa gaatcattta aagacaactt
    55861 attggaatat cctcattaca ctagacctag agattttgaa ggattaaaag taccagaagt
    55921 gcttttatca gggaatcata agaagataga tgagtggaga agagaagaat ctataaggat
    55981 aaccaaagaa agacgatttg atttatataa aaagtctaat gaaaaataaa aatataatga
    56041 aaaattaata tatatgtata caataaagta cctataaatg gaattaaaaa cataaaagtg
    56101 cttgtaataa ctattgaagt atagtataat ataaaatgtt gaaaatacgg gcgttcctct
    56161 gtttacactg gtcgggtagt taagaacgtc tatgatatct aggaggaaga aagatgaatg
    56221 aaatgctaag agcaattgag caagaacaat taaaaaatga agttcctaat tttggacctg
    56281 gggacacagt taaagtacac gttagaatta tagaaggaaa aagagaaaga atacaagtat
    56341 tcgaaggtgt agtattaaag agacaaggtg gaggagcaag agaaactttc acagttagaa
    56401 aaatgtcttt caatgttggt gtagaaagaa ctttcccagt tcactctcca aaaatagaaa
    56461 aaatagaagt tactagaaaa ggtaaagtaa gaagagctaa actaaactac ttaagaggta
    56521 gagtaggtaa agctgctaag ataaaagaag ctagaaataa ataattaaaa actttactta
    56581 taaatggggg gctgatttat cagtcctctt tctattttaa tgaaaattac agcaaataat
    56641 tatactagaa ataaatagaa atatttgttg aaaatataca ttatttatct atgaatttat
    56701 agcttttaaa atgaaaaata aaattggtaa atattgcatt atattttgta acgatattaa
    56761 aaataagaga acagtattat gtaaagtatg acgttaaaaa gatgacaata ttatagtttg
    56821 ttaagataga ttttttaagt ggaattagga tataataata taatattaat aaggagtgat
    56881 acatgtgtca aatgaatacg aagagtatct tatgaatgac aatctacata taaactggta
    56941 tccaggtcat atgaaaaaaa ctaaggagtt agtaaaaaat aacttaaaat tgattgatgt
    57001 agtaattgaa cttttggatg ctagaatccc gtttagtagt aaaaatccag acatagacag
    57061 gcttgtagga gataagccaa gagttgtcgt acttaataag agtgatatgg cagataggga
    57121 taaattgaat caatggattg aatactataa gaaaattaat atcaaagcta taccagtaga
    57181 tacaataaaa ggcgttggta taaataagat aatcgaagaa tgtaaaaatg taactagaga
    57241 aaaaatgagt tctttaaaag acaaagggag aaaagaaaga gctatacgaa taatgatagt
    57301 tggagttcca aacgttggta aatcgtctct tataaacaaa ttaacaggta gaaaaagcac
    57361 tcaaactgga gataagccag gagtaacgaa agggaaacaa tgggttagat taaagggaaa
    57421 tcttgaactt ttagatacac ctggaatact ttggcctaag tttgaagacc aagaagttgc
    57481 attaaattta gcatttagta gagctataaa ggatgagatt ttagatactg aaactttggc
    57541 tttaagactt atagaaaaac ttatgaaaat agaacctgag aagttgaaag ccagatataa
    57601 gttagattgt ctaggagaaa ctccaattga aactatggat atgattggcc ataaaagagg
    57661 gtttataaca ggtaaaaaag aactagatta tacacgcata gccacaactg tattaaatga
    57721 atttagagat ggaaaaatag gaaatataac attggaagtt ccagaaaacg ttaaaagata
    57781 gattttaaaa caaaatcaaa aatttaatgt taaaaattta aaaaagcctt ttagcaaagg
    57841 cttttttatt tttttgaaat atagacaaat atctccatat aaaagtataa attaggttag
    57901 aaaaccttta aaaatattaa tttaagacaa atatacctaa tattttgaaa attaaaatga
    57961 gtgtgattat ttaaaatttt agcatattga cttgcttgtt tcgtataata tataataagc
    58021 acaaataaat acaatatatt aaaaatttaa tttatttaat tttattaatt taataataag
    58081 ttcttattgt ttaattcaac ttacttatgc aagcgtaaac aatcgagaca ttttattaat
    58141 ttaataaggt taaaaagggg gattttataa tgggtaagac caaggatgtt atagtatttg
    58201 gatttgcgtt atttgcaatg ttctttggag caggtaactt aatatttcca ccttacttgg
    58261 gaataattac aggtccagaa tggttaattg ccttcttagg atttacgttt gctgatgctg
    58321 gattggcact tctagcagta atggctacag ctaaattcga tggaaacgta gttgaaatgt
    58381 ttaaaagatg tggtatgaag ttagggattc ttataggttg tgcagatatt ttatgtatag
    58441 gaccattctt agctatacca agaacaggtg caacaactta tgaaatgggt ataatgcctt
    58501 tatttggaac ttcaattcca gtgttattat tctgtatact tttttttgcg atttcatatg
    58561 tactaacaat aagaccttct aaggtcgtag atatagttgg acagttttta actccagctc
    58621 ttctaatagc tttagcattt ataattataa aaggtattat atcacctctt ggagatatag
    58681 tagataaacc tatgatacct aatgtatttg cagaaggtat aggtcaagga tatcagacaa
    58741 tggatgcttt tgcagcaata gcacttgcat cagtgctaat agtatcttta aatgataaag
    58801 gatattctac tattagtgac aagttgaaaa tgattggtaa ggcgggtgtt cttgcttgtg
    58861 gaggattagc tctagtttat ggaggattat gtttccttgg ggcaactgta tcaacaatgt
    58921 atggaacaga tgcagtacaa tcacaagtaa tagtaaatat aactgaagga ttgcttggaa
    58981 atgttgggaa agcgatttta gcagtagtag tatcattagc atgtttaact acatctatag
    59041 gtcttacatc tgccacaggt caatatttct ctagacttac aaaaggtaaa ttgagttatg
    59101 aaaaaatagt attagctgta tctgtattca gtgcagtagt agcatctttt ggtgttggaa
    59161 ctataataaa gatagcatct cctatactaa gtatagttta tccaccatca attgttttaa
    59221 taattttagc tttcttcaat gaaaaaatta agaatgataa tgtatacaaa ggagcagtat
    59281 atatgtcatt gcttgtaagt atactaacag ttatatctag ttatggagta gctgttccag
    59341 tagtaaattc tttacctctt aattcattag gatttaactg ggtggtgcca gttataatag
    59401 ctggaataat tggtaatttt ataccatcaa agagtcaatc taatacactt ggaacaaact
    59461 aagttttgtt taattaaaat ataatcgatt gtaaataaat gagttaacta aaagtaaaag
    59521 gagttatttg tacaaataac tccttttatt tttagattct
//
LOCUS       DAEPUT010000013        57470 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.013, whole genome shotgun sequence.
ACCESSION   DAEPUT010000013 DAEPUT010000000
VERSION     DAEPUT010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57470
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.013"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(352..1191)
                     /locus_tag="KRL22_000952"
     CDS             complement(352..1191)
                     /locus_tag="KRL22_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1271466.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMCILIVVGAITGIL
                     GLF"
     gene            complement(1215..1973)
                     /locus_tag="KRL22_000953"
     CDS             complement(1215..1973)
                     /locus_tag="KRL22_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1271467.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(2020..2493)
                     /locus_tag="KRL22_000954"
     CDS             complement(2020..2493)
                     /locus_tag="KRL22_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1271468.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2522..2938)
                     /locus_tag="KRL22_000955"
     CDS             complement(2522..2938)
                     /locus_tag="KRL22_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1271469.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(2985..4037)
                     /locus_tag="KRL22_000956"
     CDS             complement(2985..4037)
                     /locus_tag="KRL22_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1271470.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4433..5113
                     /locus_tag="KRL22_000957"
     CDS             4433..5113
                     /locus_tag="KRL22_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH1271471.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5246..5566)
                     /gene="sugE"
                     /locus_tag="KRL22_000958"
     CDS             complement(5246..5566)
                     /gene="sugE"
                     /locus_tag="KRL22_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBH1271472.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            5948..6775
                     /locus_tag="KRL22_000959"
     CDS             5948..6775
                     /locus_tag="KRL22_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH1271473.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGSKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            7597..8271
                     /locus_tag="KRL22_000960"
     CDS             7597..8271
                     /locus_tag="KRL22_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271474.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            8259..9419
                     /locus_tag="KRL22_000961"
     CDS             8259..9419
                     /locus_tag="KRL22_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1271475.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKNQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            9690..10163
                     /locus_tag="KRL22_000962"
     CDS             9690..10163
                     /locus_tag="KRL22_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBH1271476.1"
                     /translation="MLSFTFCSLPFWICYFWCGISDILDGLIARKLRQQSGIGAKLDS
                     IADFIFSVTILVTVGKNIALPMYLWWCIIAIALLWLISYSIGFFKYRTFSSLHTLMNK
                     ITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIMIKSKELNRDIKSIFM"
     gene            10449..11117
                     /locus_tag="KRL22_000963"
     CDS             10449..11117
                     /locus_tag="KRL22_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271477.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKGYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            11120..13588
                     /locus_tag="KRL22_000964"
     CDS             11120..13588
                     /locus_tag="KRL22_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1271478.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYTLSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSLISALPSAIYASHVSPKIAMAGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIAKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITNSILEDFK
                     NGSICFIKNPIAISTPGVKTRYTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNRSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLTC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(13828..15252)
                     /locus_tag="KRL22_000965"
     CDS             complement(13828..15252)
                     /locus_tag="KRL22_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1271479.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNITLLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(15271..15963)
                     /locus_tag="KRL22_000966"
     CDS             complement(15271..15963)
                     /locus_tag="KRL22_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271480.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(16018..16794)
                     /locus_tag="KRL22_000967"
     CDS             complement(16018..16794)
                     /locus_tag="KRL22_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH1271481.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLFMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSY"
     gene            complement(16791..17561)
                     /locus_tag="KRL22_000968"
     CDS             complement(16791..17561)
                     /locus_tag="KRL22_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH1271482.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQSLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(17558..18262)
                     /locus_tag="KRL22_000969"
     CDS             complement(17558..18262)
                     /locus_tag="KRL22_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH1271483.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(18517..19029)
                     /locus_tag="KRL22_000970"
     CDS             complement(18517..19029)
                     /locus_tag="KRL22_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271484.1"
                     /translation="MKKISQEKISTHIQEIPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSGCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            19355..19612
                     /locus_tag="KRL22_000971"
     CDS             19355..19612
                     /locus_tag="KRL22_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271485.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            19755..20381
                     /locus_tag="KRL22_000972"
     CDS             19755..20381
                     /locus_tag="KRL22_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HBH1271486.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(20628..21407)
                     /locus_tag="KRL22_000973"
     CDS             complement(20628..21407)
                     /locus_tag="KRL22_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH1271487.1"
                     /translation="MNSKIYYFSGTGNSLVVSKILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSFVLRLVGKNMQIATTKFFVENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(21475..21936)
                     /locus_tag="KRL22_000974"
     CDS             complement(21475..21936)
                     /locus_tag="KRL22_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1271488.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(21912..22589)
                     /locus_tag="KRL22_000975"
     CDS             complement(21912..22589)
                     /locus_tag="KRL22_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1271489.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            22822..23208
                     /locus_tag="KRL22_000976"
     CDS             22822..23208
                     /locus_tag="KRL22_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1271490.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVARESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            23211..25010
                     /locus_tag="KRL22_000977"
     CDS             23211..25010
                     /locus_tag="KRL22_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HBH1271491.1"
                     /translation="MYAPFFIRFLLSTLTLSILIAVILLAKKVFKKHISVKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(25365..27239)
                     /locus_tag="KRL22_000978"
     CDS             complement(25365..27239)
                     /locus_tag="KRL22_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1271492.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(27244..28908)
                     /locus_tag="KRL22_000979"
     CDS             complement(27244..28908)
                     /locus_tag="KRL22_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBH1271493.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKNLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESEDVIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDVNLLNKTVRLKPFHAVLLKAR"
     gene            complement(28922..29743)
                     /locus_tag="KRL22_000980"
     CDS             complement(28922..29743)
                     /locus_tag="KRL22_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1271494.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVAQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(29842..30606)
                     /locus_tag="KRL22_000981"
     CDS             complement(29842..30606)
                     /locus_tag="KRL22_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1271495.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEIKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(30603..31352)
                     /locus_tag="KRL22_000982"
     CDS             complement(30603..31352)
                     /locus_tag="KRL22_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1271496.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRICRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(31856..32461)
                     /locus_tag="KRL22_000983"
     CDS             complement(31856..32461)
                     /locus_tag="KRL22_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1271497.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGENIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            32640..33278
                     /locus_tag="KRL22_000984"
     CDS             32640..33278
                     /locus_tag="KRL22_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1271498.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            33410..34072
                     /locus_tag="KRL22_000985"
     CDS             33410..34072
                     /locus_tag="KRL22_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271499.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTPGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            34072..35253
                     /locus_tag="KRL22_000986"
     CDS             34072..35253
                     /locus_tag="KRL22_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1271500.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESILLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTIHAENCHNGGARFIIKFY
                     T"
     gene            complement(35434..38094)
                     /locus_tag="KRL22_000987"
     CDS             complement(35434..38094)
                     /locus_tag="KRL22_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1271501.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVISAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYINSGNYHADAPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(38091..38774)
                     /locus_tag="KRL22_000988"
     CDS             complement(38091..38774)
                     /locus_tag="KRL22_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271502.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(39118..40071)
                     /gene="blaCDD"
                     /locus_tag="KRL22_000989"
     CDS             complement(39118..40071)
                     /gene="blaCDD"
                     /locus_tag="KRL22_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH1271503.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEDAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMI
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(40612..42726)
                     /locus_tag="KRL22_000990"
     CDS             complement(40612..42726)
                     /locus_tag="KRL22_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HBH1271504.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMAEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTGELTQLIDM"
     gene            complement(42810..43646)
                     /locus_tag="KRL22_000991"
     CDS             complement(42810..43646)
                     /locus_tag="KRL22_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1271505.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     LS"
     gene            complement(44241..44603)
                     /locus_tag="KRL22_000992"
     CDS             complement(44241..44603)
                     /locus_tag="KRL22_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1271506.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(44902..45366)
                     /locus_tag="KRL22_000993"
     CDS             complement(44902..45366)
                     /locus_tag="KRL22_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH1271507.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVDFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(45795..47216)
                     /gene="nhaC"
                     /locus_tag="KRL22_000994"
     CDS             complement(45795..47216)
                     /gene="nhaC"
                     /locus_tag="KRL22_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH1271508.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(47246..48310)
                     /locus_tag="KRL22_000995"
     CDS             complement(47246..48310)
                     /locus_tag="KRL22_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HBH1271509.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(48295..49704)
                     /locus_tag="KRL22_000996"
     CDS             complement(48295..49704)
                     /locus_tag="KRL22_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBH1271510.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(49704..51908)
                     /locus_tag="KRL22_000997"
     CDS             complement(49704..51908)
                     /locus_tag="KRL22_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH1271511.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(51902..52276)
                     /locus_tag="KRL22_000998"
     CDS             complement(51902..52276)
                     /locus_tag="KRL22_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HBH1271512.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(52354..53784)
                     /locus_tag="KRL22_000999"
     CDS             complement(52354..53784)
                     /locus_tag="KRL22_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HBH1271513.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKAIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(53777..54085)
                     /locus_tag="KRL22_001000"
     CDS             complement(53777..54085)
                     /locus_tag="KRL22_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HBH1271514.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIKS
                     DASIGDLVEVKTITGRLVKGNLLKVNPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(54229..55296)
                     /locus_tag="KRL22_001001"
     CDS             complement(54229..55296)
                     /locus_tag="KRL22_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HBH1271515.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(55552..56925)
                     /locus_tag="KRL22_001002"
     CDS             complement(55552..56925)
                     /locus_tag="KRL22_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1271516.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIEKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
BASE COUNT        19546 a         9739 c         6775 g        21410 t
ORIGIN      
        1 taatacatta gttatatatt ataatatctc gacaatgtct taacaatatc tcgattatat
       61 attttaatat gtaactaata tgttataata ttttaattaa attaaataaa tttatatttt
      121 tttgaaatta cttaatattt tatataaaaa tgaaaaagca cctcattctg attaaaaatc
      181 tttctgagat actttttaaa atattaaata ctacatatag cttacataag tttaaaattt
      241 aatctattat aaaattaccc taattgccaa actttttaat ataaattttc caacatccta
      301 caaatataat caatagatat agaatcctaa cttacaccaa tatatattta tttaaaatag
      361 tcctaaaata cctgtaatag ctcccactac tatcagtata cacattattt ttattggaga
      421 aagacctttt tttaaagcaa agagtactaa taaagtaagt accaaaggaa ttaacccagg
      481 aaatatctta tcaagtaaat ccgtttgaag actaaattta aaatcaccac tagtataact
      541 tattggtgta gataaattaa taaacctacc tacaagtccc cccatgacta aggtacctag
      601 tatagaagcc ccttctataa ccttatttac tattccacct tgaagtatac tttcaacagc
      661 ttttttccca tacttatatc catttgtcca cattccaaaa gaaattgaag tcattattat
      721 atattgagct attacaaata atataggtcc tgcaattgat gctcctccct cagttaaacc
      781 aatacaaaca gccaacacta taggagttat aactccttga gttaaagtat cgccaattcc
      841 cgctagtgga cccatcaagc ctgttttgat agcattcata ccatctccac ttatttcatc
      901 tgctccatta gctttttctt cttccatagc tattgttatt ccatgtataa cacatccaca
      961 tataggttct gtgttaaaaa atgctagatg agtctccact tcttgtttta actcttcctt
     1021 atctggatat aattttttaa gtactggcaa cattgaatgt gaaaaagctg ttgattgcaa
     1081 tctttcataa ttgtaattag attgtgcaaa gaaaaaccat cttaaccatg attttattac
     1141 atctttcttg cttaacgttt tcttagatac ttcatttttt atatctgaca taatattttc
     1201 cccctcacat gtatttaaga tgtagcacta tcttttccgt acttaattga agtaattgta
     1261 agagcaagta ttactccaat aacagatatt actattatat ctactttaaa ataaacagcc
     1321 attagtattc ctaatatgaa aaagggcata gtaaacttgt ttccaatcaa ttttaaattc
     1381 atagcaatcc caagtgctgg caacatagcc ccaattacat taaatacatg taacacatta
     1441 tcattcatta cttccaacat accatctatc gcatttggac caaaataaac aactaataat
     1501 gctggtataa aactcattgc aaataacagt atctgtggtg gtactatatt tataaatgct
     1561 actctatcaa cattcccttt ttgaacctct ctatcagccc aatgtgcaaa aaaagaattt
     1621 actgtcatct ttccaatcca aagtacagtt gcaacagttc ccaatggtac agctattgcc
     1681 attgcagtac ttacatctag cttagatgct atagctaaag cagtacctac atatcctgca
     1741 aaagctgggt cccccatctg agctccccct gctgatataa aacctagata tatcatattt
     1801 atacctgctc ctataattgc tccttgaaca gggtctccta atataattcc cgttacaaat
     1861 ccagccaata gaggtctatt ccatgtaaaa aatccaacat aagtcaacca cggactccaa
     1921 gaaagataat aaaaaattgc tattaatact gcttgaatta gtgaaatgtg catattcttc
     1981 ctccctattt tcttttaaag atttacaaga tagtcttctt tataataatg ttcctacatc
     2041 aattttcttt gcatctggta ctatttgtat aaagcattta acatcttttg atattagctc
     2101 tctaaatatt tctttttctt catctgacac agatatattt ttataaaaac tttttctacc
     2161 aagccctgct cccatacctc caacattcaa ttcctttaaa tctaccccgc tatttactaa
     2221 acctaagaca gttttagggt atttgaccaa tactattaaa ttttcatctc cattatgtga
     2281 ttttaagact tcagcacctg attctacatc atgtacttca accttaacag ttgatggagc
     2341 tgccatttgt aaaacttgaa ctataaatgg gtcctttact actaaatcat ccacgattac
     2401 tatccttttt gctgatgtaa tcttacacca agcagtaata acttgcccat gtattaatct
     2461 atcatcaatt cttgttaatg ctatattact cataattatt cctccagatt tttaatttat
     2521 tttacaactt taaaacagtt ttaacatctt tgattcctga tatcccaact tcctcacata
     2581 aattcttcaa gtcttttaac ttcatagtat ctctgtttaa aaataactct aaaagcatag
     2641 gtaaatttac acctgtcaaa cattctaact cacatacctt agcaaattta tttattataa
     2701 tagcagatgt attaaatgga gttccgccat aaaaatcaag caatactaaa accccttcat
     2761 ccttatattt ctcaattcca tcttctaact ttctactaaa ctcatctatg ctgtcaccat
     2821 ggtttaatcc taaagtttct acattttcct gtttgcctac tattaattca gcactttcta
     2881 acattgcttt agccatattt ccatgtgtgg ctataattat tcctgccata tgaatcatac
     2941 ctttcttaac cttttttata tggattatta tttagtactc taatctaatt atctatatta
     3001 atcattatct taccaaagaa aatatccctt ttgtatactt tttcaaaata agctggtact
     3061 tcttctaaat ttattctatg tgttactaat ttttcaacat tcatgtcacc cttttgcata
     3121 tgatacaatc cagcactcca ttcttttcct gggaatggaa aggagtttcc aaaccaagtt
     3181 ccctttacag ttaattcact tcttactatc ttttcaaatt gctctctagt caaagctaca
     3241 tccccatatg gtacacctgc atacaatact gtacctccct ttttagctag caacagtact
     3301 tgaccacatg tcagtggagt accagccgat tcaataacaa tatctgcacc atctccatca
     3361 gttaaccttt ttatttcttc tacaatattc ttttcttttg catttataca aatatctgcc
     3421 cctaactctt ttgccaagtc taacttctca tcaaatacat ccacagctat tatttttgta
     3481 gaaccaaata tttttgccca ttgtattgaa aataatccta ttggacctgt accaagtact
     3541 acaacagtat ctccaacttt agcttctgac ctaaaaagac catgtcctgc tatacatact
     3601 ggttctagcg cagcggcagt ctcataactt atctcatctg gtatttttat taaatttctc
     3661 tctttcacct ttgtatactc tgcaaaacaa cctccaagtt ctttatttcc tattattgct
     3721 acattattac atcttgaata caagcctttt ttacattcat cacattcaaa acatggcata
     3781 gctggacaaa cagcaactct atctcctatt ttaaaactcc ttacttcttt accaacctgt
     3841 gccacttctc cagaaaattc atgccctaaa atttctccaa ccatatgtgg acctgtcttt
     3901 gaatattttg atatatcaga accacatatt ccagctactt ttactttaat tattacatca
     3961 tctttttcta atatttttgg tacatccaca tcctccactc ttgtgtctct tataccatag
     4021 aatctaactg acttcactat taaccacccc tactttttat ttgagaatat atccctattg
     4081 tttatatgtt aaatatctaa agcaactttc atgccaatat atgtaagcat tgtattcatg
     4141 cattttataa aattatcatt aaatgtgtgt caaagtgtgt caaaagtttc ttatattaaa
     4201 acttatgtgt gtcaatataa acgacactaa cattttatat tagttctctt attataagtt
     4261 ttataaaatg tacttttttt gttattttta taaaattgtt cggaaatttc ccttctattt
     4321 gtgatataat attaaatata aggtatcaat ataaattttc atgcgaatat cagaactttt
     4381 ttgacactaa tgccttattc aatataataa tttaactttt tggaggttgt ttatgaaaaa
     4441 agtgtatcaa ggaaagacta aagatgtttt tgaattagat aatggaaatt acttacttaa
     4501 atttaaagac gatgtaactg gtaaagatgg agtatttgac ccaggcgaaa atagtgtagg
     4561 tctaagtata gatggaattg gtagagctaa tttagagaca tctgttaagt tctttgaaat
     4621 tctaaacaat gctggaatta aaactcatta tgtaagtgct aatttagaag aagcaactat
     4681 ggaagttcta ccagcaaaag tttttggtaa tggattagaa gttatttgtc gttatagagc
     4741 tgttggtagt ttcttacgtc gttatggttc atgtgttgaa gaaggtgcta aactagattg
     4801 ttacgtagaa gcaactttaa aagatgatga ccgttgtgac cctcttataa catctgaagg
     4861 tttagaagct ttaaacatta tgactcaagc tcaatttgat tcaatgaaaa gcatgactca
     4921 aaaaatttct aacatagttc gcgatactat agctgaaaaa ggtcttgagc tttatgatat
     4981 taaatttgaa tttggattct acaatgatga agtaatctta atagatgaaa tagcatctgg
     5041 aaatatgcgt gtttataaag atggtgtaat agttgaccct atggatttaa ctgctctttt
     5101 attagataaa tagtatatac atataattta caaatataat aaacttataa ataagataag
     5161 ctatgaagta aagacttttt aaatgttgat tatttttaaa cattttctcg cctttaattt
     5221 catagcttat ttaaattaat atactctaat tagtagataa tagctttaac cctacaattc
     5281 ccaccacaat aaaacctata catgcaattc ttgatatact aataggctca tttaaaatag
     5341 ccatgcctac aatagctgta ccgacggtac caattccagt ccatattgca tatgaagttc
     5401 caagtggaag atgttttagt gctaatgaca aaaaataaaa acttacaatc attccaacaa
     5461 cagtaagtat acttggagtt aatttagaaa atccatgtga attttttagt tgaaaagccc
     5521 aaaacacttc aaacaaacct gcaacaaaca aaaataacca tttcataaat tcatccctct
     5581 tttcaaatat gtctcttatt tttccaataa aataacctga gaaatattat aaaatatctc
     5641 ccaggttttt gtccttccgt gttcacaaca aaaactatgt tgtgggtttt atctcggacc
     5701 agaccaatca ttaataattg cggaacccta taaaactcta ttaattattc tattttatct
     5761 ataataatac tatcaacata tataaaaaaa gtcaatatat gggttccata tataataaaa
     5821 ataactttta tatacctttt aatattctta ttcacttctc tccataccca tttgggtcaa
     5881 tctaagaata tctaattttt atttaatatg ttataataac ataaaaatat tgaaaggagt
     5941 aatttctatg aatttctata aaattgcagt atgtcagatg attactacag aaaataaaat
     6001 tgaaaatatc aatcatgctg tagatatggt aacagaagct gccatcaatg gatctaaaat
     6061 tgtagttttg ccagaaatgt ttaactgtcc atatgaaaat aaatattttc ctaaatttgc
     6121 tgaagaatat ccaggtgaaa caacaacaat attgagtaaa ttagctgaga aacatggaat
     6181 ttatctagtt tctggtagta ttcctgagtt agaagatgga aaaatctata atacttgcta
     6241 tgtatttgat aaaaatggag ctctaattgg aaaacatcgt aaaatgcact tatttgacat
     6301 tgaagttaca ggaaaagtta gttttaaaga atcagatact cttacagctg gaaatgatgt
     6361 cactgtaata gataccgaat atggaaaagt tggtatagct atttgctatg atattcgttt
     6421 ccctgagtta tcacgtttaa tggctcttaa aggtgctgaa atcgttatct tacctgctgc
     6481 atttaatatg actactggtc ccgcccattg ggagttatct ataagaatgc gtgctttaga
     6541 taatcagata ttctatgttg gtgctgcacc tgctagaaat atgaatgctt cttatatagc
     6601 ttttggaaat tcaagaattt cagacccttg gggaagaata attgctcaag ctgatgaaaa
     6661 agaatgtatt atttatgctg acattgatag agatttaatt cctgacataa gacaacagtt
     6721 accacttctt aagcacagaa gaactgattt atatgaactt aatactttga aataaaacag
     6781 aacataaccc cataaatcgt aaattaagtg ttaaaaaaat ttatggggtt ctcattaatt
     6841 tgatttaaaa ttaatttcat aaaaataatg ctaaaattaa tttaattaaa taatactaat
     6901 aattactaat gattatgcta attatcagca tttactaatt taatcactat tagttatttc
     6961 ttttattaaa tatctttact tttttactta ttatgtcttc tagctttaca tttggattat
     7021 ggtatttctt tctattttta gtcacatctt tctattgaat tacttgctta aaacaccaat
     7081 gcacacatgc cagataatgt tcacaattat gtagaaatct tgctctacct tcttcaatgt
     7141 tgatattatc tctcctagtt gatattatct ttcctaaaat ttcttttaat taaaaaacaa
     7201 cattagttga tatatcaagt atattttaat caactgaaaa aaacaataat aattgatata
     7261 tcaactaatt aatgtagatt aattcatttt tataatttat atacttttta attaatctac
     7321 cttatttaat taaaatcctt cctttctatt tatccatttt caacttaaat tataagattt
     7381 catcagctat atttttgcat accaataagt attaaatatc aaatatatat tctattaaaa
     7441 tttctaataa tttcatcctt gatttattta atatataaaa atatactaac tttaatgatt
     7501 aagttttgaa atataactaa aaatttgata atttattgag atttttatac taaaatatac
     7561 atactataca aacttaattt agaagggagc attcttatga acaataaaat actcgtcgta
     7621 gatgatgagg aaggtataat aacactctta aaagattact ttgaaatgaa tggttatgag
     7681 gtttacactg ctcaaagtgg aaaagacgca ttaaaaaaaa tatccaaaaa tccagatatc
     7741 attctacttg atataaacat gcctgaaata gatggaattg aagtttgtaa tagaattaga
     7801 gattatgtat catgccctat tctatttctt acagctagaa ttgaaaacac tgacaagata
     7861 aatggttttc gtgctggtgc tgatgattat attgtaaaac cttttgattt agacgaactt
     7921 ggagctagag tatctgccca tttaagacgt gaacaaagga agtcaaatca aactaaaatt
     7981 aaattttata atgatttaac aatagattac gaaaaaaggt taatttgtat atataataat
     8041 cagatttcac tttcaaaaaa ggaatttgat atagtagagc ttctctctat gaatcctgga
     8101 caagtatttg ataaagaaaa aatatatgat agagtctggg gatacaatag caatggaaat
     8161 agtgatgtta taatggaaca cattagaaaa atacgaatca aactatcaaa acatactctt
     8221 gaaaattata tagaaacagt ctggggagtt ggttataaat ggataaaata aataatatgt
     8281 cattaaaaaa agctttcttt gttcttactt tatcttcact aattatagca tcagtactta
     8341 ctactttcgc atacatttta cttaataatc tatataattc tatacaagat aagtatttaa
     8401 aaacacctat aaatacaggt attataacca tagttcaaaa caatgtgaac caatttagtg
     8461 attatgataa aacattactt aatataatca acatactcca gcttgtactt ccacttatat
     8521 tttttatagg acttttatta ttagctgata taatttttta caaggtaaaa ttaaaaacac
     8581 ccatagaaat actcaataaa ggtgcaatgg aaatatccaa caacaattta gacttttgct
     8641 tagaatataa taataatgat gaattaggta atctatgtaa tgcttttgaa aaaatgaggt
     8701 ctgaactaaa taaaaacaac ataaagatgt ggactatgat taatgataga aaacaactta
     8761 atgctgcttt ttctcatgat ttaagaaatc ccctaacagt tctaaaaggt tactcaaact
     8821 atttaacaaa atacatacca acaggtaagc ttagtgatga gaagatttta tcaaccacac
     8881 aacttatgtc tgagcatatt aacagaattg aatactatgt agaaaatatg agtaatgctc
     8941 aacgattaga agatttagtt gtttcaaaat ctatgtcgaa tataaacaag tttatagaaa
     9001 acttagatga aaatatatct atcattgcta aacaagaagg aaaatctttt acacttaaaa
     9061 atcaaataaa taatataaat ctattttttg atgaaaatat cattcttaga gtcgtcgaaa
     9121 atataatatc gaatgctttt agatatgcta gaaataatgt atccatactt atatatcttg
     9181 aacaagaact ccttaccttt gtaattgaag atgatggtat aggatttagt aaggaatctc
     9241 taaaattagc tttaagacct ttctatagag ataagacttt aaatgacagc aatgcacact
     9301 ttggtatggg tctttatatc tcaaaaatat tatgtgaaaa acatggtggc tctatttcta
     9361 ttgaaaataa ttctactaac agtgctaaaa ttactgctaa attctcaaca agaaattaaa
     9421 atgattttgt aagctttcac tgctattata taaaatttgt tagtttagaa tttataaaat
     9481 gtatttcaat ttataaccaa tatatatact attttgtaga aattgtaaga gttgcttcaa
     9541 ttataatatt ttggcaaaag gcatttgaaa caataataga aatatatatt taaatatgta
     9601 gaatagtatg aaattagaat tttggaggtg attatattaa aagttttgct aataatatta
     9661 cattctctcg tattgtgttt gcattgctaa tgcttagttt tacattctgt tcactgcctt
     9721 tctggatatg ttatttttgg tgtggaatta gtgatatact tgatggtctt attgcccgaa
     9781 agttgagaca acaaagtgga ataggtgcaa agttagatag tattgctgat ttcatttttt
     9841 cggttacaat tttggttact gtcggaaaaa atattgctct tcccatgtat ctatggtggt
     9901 gtattattgc aatagcattg ttatggttga ttagttacag tattggtttt tttaagtatc
     9961 gcacattttc atcgcttcat actttgatga ataaaatcac tggaatttct atctttgcgt
    10021 ttccattact ctatatttgc tttggtcttg atgttgcagg aattatgata tgtatcgtgg
    10081 cttttctttc ttcttttgaa gaaatagcaa ttatgataaa atcaaaagaa ttaaatcgtg
    10141 atataaaaag tatatttatg tgaaaactta gaatttgtga caaaaataat ttatataata
    10201 atgaggaagt aaaacataaa aaattatcca caagtttatg tgtaaaatag ttttaaagca
    10261 atagagttgt attgtaaagc ctttagtgca taaattacat tttaaattaa aaatgatact
    10321 gaaactgctt atcagcactg cgaattatcc gcaaatagtg aagacttttt agatttaagc
    10381 taaaagttgg gaaaaaattg agttttaaaa cttacactct tcttatatag aaaaggagag
    10441 tgttttttat gattataaaa gcaaaacaat tatcaaaaat atatggttct aataacaata
    10501 aagttatcgc acttaataat gtaaatttag aaataaactc aggtgaattt gtttctgtaa
    10561 ttggaccttc tggaagtgga aaaagcacac ttttacatat tttaagtgga ttagataatc
    10621 ctacctctgg acaagtgtta cttgatgata aagatatata taaacacact gaaaaagaac
    10681 tatctgcact tagaagaaaa tcctttggat tcgtctttca acaatttaat cttttacctg
    10741 ttcttacagc atctgaaaat atttcaatgc ctgtacttct agataaaaaa caacctgata
    10801 aaggctattt aaatgaaatt tcatcattac ttggaattgc agatagactc aatcatcttc
    10861 cccatgaact ttcaggcggt cagcaacaaa gagttgcaat tgctagagca cttattgcaa
    10921 aaccagatat aatatttgct gatgagccta caggaaactt ggacagtaaa agtggcagtg
    10981 aagttatgaa tcttcttata aaaacttcaa aacagtttgg aaagacttta gtggtaatta
    11041 ctcatgatga tagaattgca aaacttgctg atagaaaaat ttcaattatt gatggtgttc
    11101 ttatggaggt gaaatagaaa tgaagaatta cctttcactt tcaataaaag aattaaaaag
    11161 ccagaaactt atgactacat tcatcattat agcaatagta ctatcaacta ttatgacaac
    11221 tgtggttgga cagtcaattg gtatcctaca aaatttaaga attgaacaag cccgttcttt
    11281 taatggtgat agacatgtat cctttcacca actcactaaa aatcaagttg atgacataaa
    11341 gaaagatgat agagtttatc aagctggtac ttcaataact attggcagta gtaaaataaa
    11401 ggattctggt atctctgtac ttgtaaaaga gtatgataaa acaggacttt ctaactaccc
    11461 aaaattaatg aaattaaaat ctggacattt gcctaaagat aaaaacgaaa tagccttaga
    11521 tgaaaacaca ctaaagctta tgggtataaa accaagacta ggagtgacta tacctatgaa
    11581 tttagatatt tcacttttaa atgataccat accaccatat aattacacag ctaactttaa
    11641 attgagtggc attttagagg atgattatac aggatatgta agtggtatag taaatggtat
    11701 tgtaggtaaa ggtacatcag aaaatctatt acctaagaga tatactttat cctctttgga
    11761 ttttaaaata aaacagcaag aaaagtttca agaaatagta aatcaattag ctaaaaaaat
    11821 aaatctttct cacaattcaa ttcaatataa ttggatttac ttaaatgctc ttaagataca
    11881 gtttgaaaaa gatgaaaata gttctaatag tgatggtata tctatgatta tattggtatc
    11941 tttatttgtt gccttattgg ttttactggc ttctggactt gtaatctata atattttaaa
    12001 aatctctgtt acaaagaaaa ttaaagagta tggatgttta agagcaatag gagctgaacc
    12061 aaaccagata tataagatag ttattttaca aatcttaatt ttatgtactg ttgccatacc
    12121 tattggagct gtaattggaa ttatatcttc gaaaggcata actggaatgg tcactaatat
    12181 cttaaatcca gatatacttc tagcaaatga taataaagaa attactgagc ttatacataa
    12241 aaatacaaca gcatatatgt tcccattagt attaagcact aatgtatctt tgattttttc
    12301 acttatttca gcattaccat cagcaatata tgcttcacat gtctctccca aaattgctat
    12361 ggctggtagt actaccaaaa tcaaaagaaa aattaaaaga gaaaaaacaa taaaaaactt
    12421 tgaaagacat ctagcatggc taaacttaaa aagaaataaa ggaagaacta taataactat
    12481 actatcatta tttatgagta taacagtatt cgttgcactg agtgagttct ctaatgtatt
    12541 agatgtatct aggtcagtaa gtaatttaaa agaaggagat ttttccttaa caaatgaaat
    12601 atctggtttt gataaatcaa cactagataa aatagctaaa atgaaaaacg tcaatcgcac
    12661 ttcctttata aagtactctg aatacaaaca gggtgaaata gatacagata taaattttga
    12721 aaatagtggt gagatgttaa aaatcattgg aattgatgag caaactttaa aagacttaat
    12781 gccttctatt acaaattcta tactagaaga ctttaaaaat ggttctatct gttttataaa
    12841 aaatccgatt gctatttcta caccaggtgt aaaaactaga tatacaaatt taaaacctaa
    12901 agatagtatc acaatcaaca aaaaacaact agatatatat agtacagtag ataaaatgtt
    12961 ctttttacaa ggcaatggct ggataaatgg tgttgatgtt attgtatatg attctgttta
    13021 taacactttg acaaataaaa acaagttcaa ccagataaat atttatgcta aagataaatc
    13081 aaaattagaa caaataagat tgtctattga acagatttgt gaaaataatc ctggctctca
    13141 ttggatatca tatattgaat cagataaaca acttaaagag agttttaaac aaatagaatt
    13201 tctagcatgg gcagttatat tatttgtggg attgattggt actttaaaca tcattaacac
    13261 aactcataca aatataaata ctaggactaa tgagattgga gttaaaagag ctattggtat
    13321 gagtaatagg agcttatata aaatgttttt atgggaaggt gtttattatg gaatttttgc
    13381 tgctatattt ggttcaattg ctgggtatgc cagtgctatt attataaaca tggcaactat
    13441 agaaaagctt gatttcacta atataccaat tacttcaatt ttacaagcta ctattatttc
    13501 tgtacttaca tgtattatag ctactcttat tccgttaaga aaagttaaaa agatgaatat
    13561 aattgactgt atagatatca atttataact attttacaga taataatata aattaaatta
    13621 tcaatgactg tctctatttt ctttcaaatc taactaataa atctttttaa ctataatata
    13681 agctttaaaa aaggcctgtc tcaaaataga gataagcctt ttttcattgt cgaaataatg
    13741 aaaatatatt taacttcaca aaaaaagagt gcctcacgaa ttaaaaattt cgctttgaga
    13801 cactctcctt taatttaaaa tatatagtta aatgctatgc caaaatttca cacatgctcc
    13861 acctgatttt gaattttcta ttttaacaga acctccaagc tgttccacta attgtttgac
    13921 aatgtaaagc ccaagaccag aatgtccacc ttttgtctgc ctagcttcat ctcctcgata
    13981 aaatttatca agagcctttt ttaaatcttt agagctaaac cctctaccag aatcacaaat
    14041 ctcataagaa atacaatttt tttcatcctt tacagtaata ctaatattac cacctgatgg
    14101 agtgtattgc agactgttgg atatgatatt atcaaaaatt cgtgtcaacc tatccacgtc
    14161 gatttgaatt ggggattgta tattcccctg cattttcaat ataagttcaa cttccttttg
    14221 atgagcctgt aattcatagt cttgcacctt ttgcctcaaa aattcaggta aatttatagg
    14281 aacaagattt aattgtatat ttgacttttc taagtcagac gtatattgca tcttttggac
    14341 aagagcagca cttttttctg tattttctct tatcactgta agatacctat gaagtttttc
    14401 attgtcatct gtattattac caataagtgc atctgtatat cccaaaataa tagaaagagg
    14461 agattttaaa tcatgtgcta gagcttccac catttcaaca cgttcctgct ccatcttcca
    14521 ctgtgcagat aaagagcctt ttaattcgtc tttcatttca gaaaatgcac tacaaagttt
    14581 accgagttca ttatctgaat aatagtcgat ttcaaaatca aggtcctttt cttttatctt
    14641 cttggacgca tcaatcaata gatgtaatgg ttgattgata ttctttacaa agcgcttaga
    14701 aagccatcta gtaaaaccca cgatatatag aaatggagaa aacagagcca ttataataac
    14761 tgcaaataca aatctccctc taatatttgc aaaggtgatt ttcacttggt agaatagaat
    14821 aacagctccc tcaatctttc cattatcccc tttgattgga acagtatgga tataaccacc
    14881 tttacgaaca gttttattga taaaattatt aaataattct tcttttgttt taaatagttt
    14941 tttggggtta gtaccatata aaatattgcc attattatcc acaacttgat atagcatatc
    15001 atccccacga atcgttcttt ttaaaccttc ttcattcgat tgtgataaca aagttatgtt
    15061 tttttcattg atatattttt caattctagg aacttgtcgc tcataatagt ttggtggata
    15121 gatatcctta tttaaggaat gaatatacaa atagagagca aatacataag taatcactgt
    15181 ggcaactata ctggctatta taataaaaat aaaagtatgt ctaaattggg taataaggga
    15241 ttgatttttc atttaataac ctctctctct ttacatttta ttccacttat acccaatacc
    15301 ccaaactgtg gaaatatatt ctttttctgg tgtcacagca gaaaacttag ctcgtatttt
    15361 ttttactcgc tcaacaacag ttgaggaatc accttcagaa tcacaccccc atactttttc
    15421 atagatttgt tctcttgaga aaacttgtcc tgcatggagt gctagtaatt caacaatatc
    15481 atactctatt tttgttaaat caatattctt accatcaatt ttaattgcac gttccttcat
    15541 atataagcat aacttcccaa aatacaaagt agatctcttg ttctcttcat tgatatactg
    15601 tgaacgcttt tccctacgca gattagcttc aatccttgcc ataagttcac gcagtccaaa
    15661 tggctttgtt acataatcat cccctccaaa ggtcaaccct ttgattttgt cggtttctga
    15721 ttgctttgca cttaaaaata taattgggca taaaacatca tctctaattg cctgacatac
    15781 ctcaaatcca ttcattttag gcatcataat atccagtata ataaggtcag gctcctgttt
    15841 tgataactct atacctgcct gaccatcata agctatcaac acttcatgtc cttttgcctt
    15901 caattcatcc tcaagtagca ttactaagtc catttcatca tcaataatca atattttact
    15961 caatataaca ccacctttct cttatgggaa ggtcagtatt aaaacaatat tcgtctacta
    16021 ataacttttc cttccctccc acattttaaa ccaaataacg cctcctatca agaatataat
    16081 caaacctatt gctactacta taagctctat actagctgtt tgcatcactt tagagtaaaa
    16141 tgcctcagtt gaaatagttc cagcttcttt aataaaataa attcctggaa gcatacctag
    16201 ttttactggc catgtccatg gaacaaatgc ccatactttt tcaccaacgc tagttaatcc
    16261 aagtattgct gccatcaaaa ttccaccgat actaatacca atagatgcac ccatacccca
    16321 tgcaaaactc acccaaagat gaatagctaa tagtggaagt gtcccaatca ccacaagtcc
    16381 tgctgctgac aggaataacc atattgttgc tccagatggc actgcaatac tcattcctat
    16441 gcaaagtatc aacgtagcaa taaatgtgca tatagttagg caaaacagaa gaaaaagaaa
    16501 ttttcccaga tataatctaa cacgagaaat acctacacat aaaaaaccat taaaatttcc
    16561 agcaagctct tcctcctgca ctataaatcc tgctaaaata cctactccaa taggaatgat
    16621 gaatacagtc catactgtaa aaaatccttc aaaagcaaat tcttgtgtac ttccagattt
    16681 agttgtgaga taaaaaacca cacataatga aaaaataata ggcataaaaa gagtaagcca
    16741 ctggacagct gtcctctttg ctcgaagcca ttctgatgat aatagcttta tcatttgtca
    16801 tccctcctat tgaaccaagc tgcagtaagt gctgttaata ctataaacac aaccaaagaa
    16861 acaacaatcc caataggaat cactgaagta ttcaaaagtg ggtctccagc ttctaatata
    16921 gtaccgttag gatgtatgtt gatgattggg cataccattc taactgccca actccaaggt
    16981 actgcaatcc aaaatggttt tgtcgcagca aggacaccaa atatcatacc taaagctcca
    17041 actcccatac ttaggaacat acctttccat gtagctagcc atagctgaag tggaagtata
    17101 gcaagagaaa caacccagca tacaatactt gcccctataa tctgtccaaa aggaactgga
    17161 ccagctttca atattaaacc agttataatt gttacgacta ttaaaactag cgttgaaata
    17221 aaactgtaga ctgccatagc tataacttta ttaatccaaa gtgtcatagg agacacattg
    17281 tgtgtacgta aagcacgata atttccagct tttttttcct ggaaagctac caaagtagca
    17341 aacaatgcaa atccaatagg cagaaataaa aatgaccacc agttaaaaat taatgctaaa
    17401 agactttgcc acgcccaaga agttgtttga gataatggat tttgcatgag tgttgattgc
    17461 attataaatg catatgctgc aaaagacact gggaaaaaaa caataagttt acccataaat
    17521 gttcttttat actttaaaag ttctgattgt aaagcattca tctgttttgt cctcctttaa
    17581 gaataacatc tgtaaaaaat tcttctagat tttcattagg gtcaggcatt ccttgaaata
    17641 atagtcgtcc tccatttata attcctatat tatctacaac ttgagcaacc tctgatagaa
    17701 tatggctaga aagaattaca gttatacctt tttttggaaa agaagcaatc aattcacgca
    17761 attcttgaat gccaaagggg tcaagaccat tggttggttc atctagtatt aacaactctg
    17821 ggtcactcaa aagtgcaata gctattccta acctttgttt catacccata gaaaattgtg
    17881 aagctctctt tttacctgta tttttcaaat ttactatttc caacacttca taaattttat
    17941 ctttaggtat tcccaatatt tttgtatgta ctaacaaatt ttcctctgct gtaaggtttc
    18001 catacaatgc aggggattct attaaagaac ctatttttgc aagagattct cgtttccaag
    18061 gctttctatc aaaaataata cgaccatttg ttggacgaag aagaccaaca agcattttaa
    18121 gtgttgtgga ctttcctgct ccatttggtc ctaaaagtcc atatatacta tttcgttcaa
    18181 tttgtagaga aacattgtta actgccattt gttctccata tctttttgat aagttttttg
    18241 tttcaagaat taaatctttc atattaattt ctcccttctt gtaatacctt aaatctgtta
    18301 ctaagagaat actaacatga aaaaataaca attctataac acctactaat tttaataaaa
    18361 tttaaaataa aaaatagagt taccaatttt attttggcaa ctctatttaa gtttatgttt
    18421 tacagttata ttatatttaa acttagtttc attatcacac taacttcaaa tttactctat
    18481 aatctttaaa tcaaacacta atttattaat caaacactaa tctattaatt tatatttctt
    18541 tagacatcta atatagtttg ctactaaata ataattattt atatcatatt tatctaatcc
    18601 tttaaaagaa gttatttcat cattaagctc atcactacct tctacaaaaa cacaacctgt
    18661 ttcaaattcc atacctacaa taatcttaca gccactataa atttcctctt gagtatcgta
    18721 caattttttt gcatttcctt catttggaat tgtaaataca ataggtttta attctttatc
    18781 actggaaatc ttttgtgaaa aaggcttgtt taacttaata ttattgataa ctacatgttt
    18841 aaattcctct gaagtttctt ctactattac atattttcgc tttaaaaact ctattatttc
    18901 taaaacagac ttagaattta cttttaaaat acttttatat ttttcatata aagatttcca
    18961 ctgttcaatt ttttcctgtg gtatttcttg gatatgtgta cttatttttt cttgagatat
    19021 ttttttcaat taaactctcc tttcaatact taaatattct tatgaatctc acatgactaa
    19081 agttacaagg tttctactta atagaatttt gcatacttaa atatgtctta ttaattctct
    19141 acaggatatc tccgtagttc ctacgattct tacataagtt acttatttta aattgttatt
    19201 agttagatta taaaaattat ttattttatc actaatataa tactcttaaa aactttacaa
    19261 atcaatttaa atttgctacc ttttatttat aacaacttat agtacatttc tcctatgctt
    19321 ttcaatatat tacttttaaa aggaggtttt cattatgatt ttaaatagag ctgagctttt
    19381 ccgaggatat tctttaaata gatttaacga gatatgcaat atattatcag taaataaaat
    19441 taaatataag tataaagtga aaaataatgc ttactctaaa aaaccttttt ttaatgaaat
    19501 aacacttggc aatttaggcc aaaaggaaga tttctcttat gagtacttaa tttatgttca
    19561 taaagacgat tatgaacagg cagagtctct aataaattct aagttgcgat agattatcta
    19621 taaaacatga cattctgttg tcatgtttta tatgttatta tactttcaaa tatgctacta
    19681 tattttcaaa attgtgtgct ttaaaactag ctttttttag taatttaaag cttaaaacta
    19741 aggagactcg ttatatgaaa ataaatataa aatcaaagtt aagtgaattt attaaacaga
    19801 acaatctttt tgatgacagc agaataatat cctatcttcc taatataaca atagaaacag
    19861 acaaaataaa aactataatg attaatgagg ttgtcccaac taataccaat gacgattttt
    19921 atagtgtaga taaagatgct gattatttaa aaactactat tcctttattt gacagtgcag
    19981 gaataaaagt atctaacata aatgatatcc tagatatggg tatctatata actaatgcag
    20041 taaaacttcc taaatcagaa tatacaataa ctcgtgatac aattaaatta catatgccta
    20101 ttttagaaga agaaattaaa ttatttaaaa acctagaggt agtaatgtta atgggagatg
    20161 ttgcaaaaaa atcttttaat atgattacta aaaagcatat aaaaaagaat gtcatccctt
    20221 ccatttcaac atataaactt cgtaataatg aactttatta tgataattta agagtatttc
    20281 catcatatat tatgactggt ggaaacatac tgattgaaaa atcaaaattt gaaatggcat
    20341 cagaagatat aaaaaaaatg ttcgagatta taaacggttg atattacaaa ataataaaaa
    20401 ctaatataaa ataaaaagtg cctcaaaaac ttctatttat gaggcacttt tattttatat
    20461 tagtgtaact atatactatt aacataattt attatttata ttgttctttt taatctctat
    20521 tccatttagt ctaggtaaca ttactcttta caagattact ttatatttct tttatatctc
    20581 taacgttttt atttaataaa acaattatta atacaagtca attatatcta tttatctaaa
    20641 aatatatctt ttacagtaat atctggatgg tgatacttct tcctattcgt taaaaaagat
    20701 ttttttacat taatagcctc ttttggacac cagtgaaaac aagctaggca tctttcacac
    20761 tcattacccc actttggctt tttatcaact atacttatat tctctacagg acaaaccctt
    20821 ttacatgtcc cacatccatt acatttattt tctacaaaaa atttagtagt tgcaatttgc
    20881 atattcttac ctactaaacg aagtacaaaa ctatctatat gtgactttaa attgtttttt
    20941 ccttctatat ttccaatctc caagttattg atacattttg caatctcagc taccctatta
    21001 gtctgatttt tcaatctttc ttcttcaaca tctggaggtg ttatcaaagc atttccaggc
    21061 atattgatta aaaaaccagc agataatttt ttcccccttt ttttaagtaa cttatctata
    21121 gtaaataaac tatgtccagc taccccatta caagtggcaa tggcatatat atgagtatta
    21181 atattaaaat ttaatttctc tacaaaagac tttactatat caggaacatc agcaaaataa
    21241 acaggaaaaa caattaccaa tatatcttca tttatgtcta tattattttc ttttctatgt
    21301 atagctaaag gtataacttc tttacttcca tttaacgttt cttttaaaat ctttgaaact
    21361 actagcgaat ttcctgttcc agaaaaataa taaatcttac tattcattct tatccctctt
    21421 tctatatttc tacatcatca atagttaaaa agtctcttaa aataggattt atatttactt
    21481 tccaattcta tccaaaatat cagtaaacaa aggcaattct tcatcagaga tagatttaaa
    21541 tgtctctgtt gcatatatac ttgcaatttc atttaatggt tcttctaatt ctctacctaa
    21601 atctgttagg aatatttgaa acttacgtct atctttaaca tctactttac ggacaattaa
    21661 tcccttattt ttcataacat ctaagattct tgtcgtatta gatttatcct tacatgattt
    21721 ttcacataaa tctatctgag aaatgccatc ttgctcccat agaaacctta ataacgcata
    21781 atggtcagtt gttatatcat atccattttg tttaaacatc ttttttaaat catcttttac
    21841 ttttaacgaa gtacttacta acttagttgt agcttcatat agtttctcaa aatctttcat
    21901 tttacctcca tttaaataat cccttgctcc tcccatctat caattattcc cttatattgc
    21961 tcaatatctt taaaagccat tggctttaaa acagcattta tagcaataaa attatagatt
    22021 tgagaaagca caggtggatt tttcttttcc tctatgcaat aaataaattt tttagatacc
    22081 ttttgtatct ttgattctac tttttcagtt ataggatttt gattaaatcc agtttttata
    22141 gataaactac cacaaacata acctcccgaa tctaagacca tggattttat aaaagaaatt
    22201 gcttttgaac cacgtgcatt ttcatatgta gtaactgcta tacatggctt acgatacaat
    22261 aatctttcaa gcatcatatg tgctctatct gtaaacacct tgaaaagtcc agttacacta
    22321 cttccataag ttgggctacc aaatataaca ccatcactct tagtaattat atcatgaata
    22381 tactctactt tatcattttg attgatacac ttgcccattt tgtaacaatt taaacaacca
    22441 atacaatatg atggatttac ctcacttaaa tcaaaataat taatttttac atctggtatt
    22501 aatctttcta tatctttata caagtaagtt aaaacttttg atgtagctcc attttttcta
    22561 gggcttccat ttataactgt aattatcatt tctatatctc ctttttagtt gttatatcaa
    22621 caataagtat atcaactata tttttagctg tcaatataaa ccatttattt aaagccatac
    22681 ttacacagct taaataaaag ttttatttaa ctacatgtgc ttatttaatc aactataaat
    22741 gaattatttt taataattga caaactaaat taatgataat atactttatg tattacaaat
    22801 gtaagtagaa ggaggtatag tatgaaaaag ttaccacata tttcagaagc agaatatcaa
    22861 gttatgaaaa ttatttggaa atatgctcct atcagcacta ctgaagtaat tgaaaagttg
    22921 gtagaaacaa gtacatggag tcctaaaaca attcaaacaa tgttattgag attagttaaa
    22981 aaaggagctt taacatatga aaaaaatagc agagtattcg tttatactcc acttgttaaa
    23041 gaagaagaat acgtagctag agaaagtagt tcttttttaa atcgttttta taatggtact
    23101 cttaattcta tggtactaaa ctttttagaa aatgataaac tatctgaaga tgatattgag
    23161 gaactgagag aaatcttaaa taaaaggacg actaaggggg ataaataaat atgtatgccc
    23221 cattctttat acgattttta ctcagtacat taaccttatc aatattaatt gctgtaattt
    23281 tacttgccaa aaaagtattt aaaaaacata tttctgtaaa gtaccaatac aatattggat
    23341 ttatattgct tataatgtta ataattccat ttgtccctct taaatatatt aatcttggaa
    23401 atgtatttaa ctatttatat acttttaatc aacttggaag cagtactaat aggacttcta
    23461 tgataaaaaa tagtccaaat tctataatta ataactcaaa tgcattaaac gatttttcag
    23521 tatccctaaa ccaagttaat tttgatagtt taaatatttt attactaata tcatggataa
    23581 ttggaatttt aatcatgata gctattacta ttcattgcaa cattaaaata aaaaatatga
    23641 aaaaatcaat acaaatttta agagatgagg agatagtatt tatatttgaa aagtgtaaaa
    23701 aagatattgg tataaataag gattttatac tatgcaaatc acctattata aatacaccta
    23761 ttacatttgg atactttaaa ccacacatta tattaccaga taagtctata tctaaattat
    23821 ctttaaaaga tataaaatat atcttacttc atgaattaca acactttaaa aataaagata
    23881 tactgataaa ttatataatg tgcttccttc aaatattata ttggtttaat cctcttgtat
    23941 ggtatgcatt taaagaaatg cgtatagacc gtgaaattgc atgtgatatt tcagttttaa
    24001 aaaagcttga taaagatagt catatagaat atggacaaac tctaataaac tttgtggata
    24061 atatttcaag accatcaaat cttacactta catcagatat tggtgggtca aaaaaacaaa
    24121 taaaaaagcg actattgaag ataatggatt ttcataatga atcaaatacg ttaaaattca
    24181 aaagcatttt aatttttaca ttgatagctt taattgtatt tggaaatatt cccaaactat
    24241 ctattatggc agatatcaac gaaaaatata gacctacaaa tgaacaaact gtgtacgagg
    24301 acttaagtca gtattttaaa ggttttgatg gaagttttgt tatgtatgat ttaaaatcca
    24361 agcaatatca tatttacaat aaagaaaaaa gtaaaacaag aatttctcca aattctactt
    24421 ataagattta tagtgcctta ttgggattgg aaaatgggat aataacaaga aataattcac
    24481 atatcccttg ggatggaaag catcattcta atagttcttg gaatgaagac caagacttat
    24541 tttctgctat ggaaaactcc gtaaactggt actttcagac tctagataaa aaaacaggtc
    24601 taaaaaacat acaaacttat cttaggcaaa ttggatatgg taattatgat gtttcaggtg
    24661 gtatctcaaa cttttggcta gaatcttcat taaaaatatc acctattgaa caggtagaat
    24721 tacttgaaag tttttataca aataagttta aatttgaaga taaaaatata gaaacagtaa
    24781 aagattcatt gttaatatca aaaaaggatg gggtatcact ttttggtaaa acaggcactg
    24841 ccaatataaa tggaaaagat gtaaatggtt ggtttatagg ttatgtggaa aaaaatgaaa
    24901 atacttattt ctttgctaca aatattcaaa gcaaagatta ttctaatggt agttcagcat
    24961 ctaagataac attatccata ttaaatgaca aaaaaatcta taatccttaa tatatttact
    25021 gtacattcta aaaaattcac ataattttca tattaattat caattaaatt catatacaag
    25081 gcttattata taaacataga agatagtaaa actagcttaa aaacataata taatacccta
    25141 tacaaatagt ggcaactctc cctcacatcc tcaattgttg ccactattta attttttgta
    25201 tgaagttaaa tatattttca tcatttcaac aatttgggtg caatacaatc tctattttga
    25261 aacaacttct ttaattgttt tagagtttat gaattatttc tcatacttta aaaagattga
    25321 attaatcttg ataatcttct tttgtagtca ttacatatca cctactactc aacacatatt
    25381 ctttgaccta tttttacatc cttgtttata tccaaaatat ttaccttctt accatctgga
    25441 aacaatacca ttgtcaaagt agactttcct aattcgtgta ttctctttaa atcaacatta
    25501 acaagaacat ccccctgttt aaccatatct ccttgtttaa cagcaacatc aaagccatct
    25561 ccatttaatg caactgtatc aattccaaca tgaattaata cttctccatt agttccttta
    25621 atcccaaatg catgtccact tgaaaacact gtttctaatt tacctgaaat aggagaaaca
    25681 atttttccat ctataatatc aatagcaaaa ccatcaccta acattttttt agaaaatgtt
    25741 tcatctggta cattttctaa tgcaacaatt ttccctttag ctggagacac aaagttttca
    25801 ttattttcat taaacactaa ttcttcgtct tcatcttcat ttatagcttc tttaggcact
    25861 ccaaataaac atgttacaat aaagcagaat gcaaccacaa atattgatac taataagtat
    25921 gtgattaaat tatatccatc atagatatac attaaataag aaggtaaaac tgctaatcca
    25981 tatgaattag attgaatatg taaaattgat aatattgctg ctcctaaacc tgaagatgca
    26041 cacataataa tcaaaggctt taaattatat cgaagctgaa tcccaaataa aacaggctca
    26101 cttataccaa aaagttgaga taacattgct ccaaccgcag tttgtttaac ttgattattt
    26161 ttagattttt tcataaatgc tagacatgtt ccaatattcg caaatccata cattgcacaa
    26221 agagtaataa gggcattaaa tcctgtattt gctaatagtg atgtttcaat cattacataa
    26281 gtatgatgta agccagtaat aacagctaat ggatatgtaa atccaataat aaatcctcca
    26341 attcctaaag gcaaatcaat caataagctg atgatatcaa ccatttttaa ttctattgta
    26401 tgcattatag ggcctacacc taacaaaata actaacattg ttattagcat aacaaaaaat
    26461 ggtgtgaaaa taaggtctaa tacattaggc atatgtttac ggaaccattt ttcaagatta
    26521 gctccaataa atgctgtaac aatagctgtt aaaacacttc cttgacaacc tacaatagga
    26581 ataaatccaa atgccataat tgcttcaatt tcatttgatg ggtcagcaac agaatatgca
    26641 ttaggaagta ttggggaaac taacataagt ccaataacaa gtccaataac aggtgttcct
    26701 ccaaatactt taaatgctga ccatacaata attgctggta aaaaagcaaa tgctgtttct
    26761 gtaagaactg aaacaagtgt ctgaatatac aatggaatat ttgcagaaga cattccaaat
    26821 aatccaagta cattatcatt aaacaaacaa ccctttaatc ccaagaataa tcctgttgct
    26881 gcaataactg gaataatagg aacaaatata tctgctagag ttctcataac tttcttaaat
    26941 ccagtttcat tatttttaac taattcatct tgttcttttt ttgataaagt ttttaatccc
    27001 attttttcaa cttctgcata aactttatta actattcctg ttcctaaaat aatttgatac
    27061 tgtccagaag taaagaaaac ccctttaacc tcatcaactt tttcaacttt cttatcatta
    27121 ataatttctc tatctttaac catcactctt aatcttgtgg cacaatgtgt aatagaaata
    27181 atattatctt caccaataat tttaataagc tcatttgcta ttttattata tttattcatt
    27241 tttctacctc gctttcaata atactgcatg aaatggtttc aaacgcactg ttttatttaa
    27301 tagatttaca tcatctaaat tttggaatac aatatcatat ttttcttcta ctcttatttc
    27361 tacaggttta tcagaaaaat tataataaca atcaataact accaaatcta attgccttct
    27421 atacgcaata acatcttcac tttctatatc aataggttct attgaaccat aaatcaaaca
    27481 atcagaatac tcactatctt gtctcaactt tatcatcttt ttataaaatt ctaaaatact
    27541 ctctgaattg ttaatctgac tctgtgcatt aatatcttta taattttcaa taacctttaa
    27601 ccatggtgtt gtatctgaaa aacctgcatt ttctttatct gcccatggaa atggcgttct
    27661 tgcattatct cggcttctta aattcacaaa ttctaacgct tcttcttctg agtaaccttc
    27721 atctattgaa cgatagtatt ggtcaatgct agataaatca ttaaaatcat ttatggtatc
    27781 tcttttaaaa tttgtcattc ctaattcctg cccctgataa ataaatgggg ttcctcttaa
    27841 aaagaaatac attgctccca acatttttac tgcatcatca ttcctttcgt attgcaaaag
    27901 atactttgtt gtagctcttg gttggtcatg attttcaata aaattagctg cccatccatg
    27961 ttcctgaaca tacatttgac tatctaaaat gcattttctt aaatctggaa ttgtccatga
    28021 aattctttta aaccactcac taccagaagc aacatctaag tcagcatgtt taaagtcaaa
    28081 gaccattgaa aagaaaccat cttctccaat aaaatcacct aactggtcat agctaatacc
    28141 tgctgcttca gcaacagtca tacaatcata ttttttaaac gtattttctt ttaattcata
    28201 aagcattttt tctattccag gctgatttct aactgttttt gtacatttaa caagaccatc
    28261 aacaccatca ctttctaaac tttgaaaact taaattcttt ttgatgaatg taatagcatc
    28321 aactctaaat cctgccactc ccatttgaga ccaggtatta atcatttggt aaagttcact
    28381 tcttaatatt ggattttccc aattaaggtc aggttgtttt ttaccaaaag aatgaaaata
    28441 atattcgtct ctattctcta ccttttccca aacacttcca ccaaaaacag acctccagtt
    28501 atttggtaaa tcgtttcctt ttttaaaaat ataataatca tgataaggac tttctggatt
    28561 ttttaatgct tcttgaaacc aaggatgttc atcacttgta tgattaagaa ctaaatctaa
    28621 tataattttg attcctctat ctttactttc tttaattaac tcttttaaat cttccatact
    28681 tccaaattca cttgcaatat ccaaataatc actaatatca tacccattat cgtccatagg
    28741 tgatttaaaa attggacata accacaatga tgtaatacct aaatttttta aataatctaa
    28801 acgagaaata attccctgta aatctccaat tccatcatta ttactatctt gaaagcttct
    28861 tggataaatt tgataaacga tttctttttg ccaccatttc ttttccataa attactcctt
    28921 tttatatgat atttcttctt tttaattctt tataaattcc attatcgaat atgtcctcac
    28981 atatagatgt cgctatatct ttaagttgtt gatgactatt tttcattgca attgtaacgt
    29041 ctgatgcttg aaacatgaca atgtcatttt gaccatcacc aaaacatatg gtttcttttt
    29101 gagctactcc taatctttct tgtaatctct taattgcttt gcccttatga aaatcttttt
    29161 gaataatttc ataatactga ctagaaatat ctctctgtgc taattccatt ttatcttgta
    29221 gtatatcttt cacttcgtca aatacctttt catttgacca taaacaaatt ttatgtatat
    29281 cttgtgactt atactcttca atgttatttt catatgttat tttttcttgg atatgttgtt
    29341 tatttataca agaattagtt cctttcaact gattcattgt ttcaaatatt tctttggctt
    29401 tttgattcat gaaaactttt tcctgactct caatcgaaaa agcaacttct ctctttttta
    29461 ataaacaaac aacttccttt atcaatcttt gattaaaaga ttgattataa agtaattcac
    29521 catgatattg aatgtaatta cctcctcctg caatatatcc atcaactcct aatgataaaa
    29581 catcatcttg tattgtaccc atacttcttc cagtacaaat aacaacactg caatgattct
    29641 tttgacataa acgtatagca tgctttgcag attctgggat tccatatacc tcatctctaa
    29701 gcgtaccatc tatatcaagt attaataatt tgtacaattt catcttcctt tcttactatc
    29761 aaaatcataa tagcattcaa aaaaaaagat atcaatattt tgatatcttt taaaaaatat
    29821 gttcattttt agcacaaatt ttcattttcg gggaatatgt tcactttcta aatacatctt
    29881 gtatttaata taaagcagtt caattaaaat aaaataaggt gttgttacat cgtagtccag
    29941 ttgtttatct acagaaatag atatagattg aatatacagg ttttcatcac ataatcttgc
    30001 taaaggatta cttatcattt ttgtaataga aaccatataa attcctttca ttctcatttc
    30061 tttagcaaaa tcaataattg tagatgcatc tccattcaat gaaataaaga aaatcatatc
    30121 atctgttttt ataaaatgat taagtgcctg aatcatatca taaccataaa catcatatat
    30181 aattttccct gttggtaaga aaatcctttt tatctcttta gcaactcttt cctgagaata
    30241 accttctcca aagacgatta tacgatttgc ctttttcatt ctttcaaaca taatcgaaca
    30301 atccttcttc tctatatcat ctatcacctt attataacaa tccattaatt gatgtttact
    30361 ttgattttta tattctactt ctgtttcatt taagcgtata ataactctta attcactata
    30421 tccaggtaat tgtagttttt gagcaaaacg agaaagtgca cttgtagata tatggtattt
    30481 gtctgcaaat tcatctatag aaagtttaat acaatcttct ttatgattaa gaatacactc
    30541 acagatatac ttatcatttg ctgtaaatga attataatat ttattgaaaa gtccttcaat
    30601 tttcattctt ttctccttct atactctatg taattcatat gaagcaaatc taatagagca
    30661 taaaatgctc ctacgacttc ataagatata gcttgtaatg tatcaagttt ttgcgtttca
    30721 acatacagat tatactcaca aagtgttgca attgtattat tatcaagcct agttaaagaa
    30781 atcgtatgta tatgattgtt gataaatttt gcaatttcaa ttcctgcttt tgtttctcca
    30841 gacaaagaaa tgataataaa taaatcactt ttttgaaatg attctctcat aaattcaatt
    30901 tcacctatat caaataagtc aataacacat ttacctactg aaagaaatat tctctttatt
    30961 tcttgagcta aacttttctg ttcattacct gtcccataaa tataaattgt ttctgcatca
    31021 tatattattt tacaaatatc ttgaaatgat attttttgta attcattcat taatagtcga
    31081 taattctcgc aaacatcatg aaaattatta tcattattaa caaattctag ttgattattt
    31141 ttaagtaaat actttaaatc agagaatgaa tctaatccaa tttttctaca aatccttaat
    31201 aaagtagctc tagaaacatt acattcattt gcaatttttt cacacgaaaa attacggtat
    31261 tctctttgac aaatcaatat ttgtttaata ataattttat cattttcatt taaattatca
    31321 taattttggt taactaacga ttctaatctc attttttcca ctccctaaat attattttaa
    31381 tatacattag ttgctttttc tagggaagag ttttaaataa taaggataaa ataatcattt
    31441 gattttattt ttattaaaat aaaaataacc tgctaaaagc aggcaccaaa aagtacttat
    31501 cctttcgaac atgtacttta gatattgctt tcttcagaag cttcatctct tcatactcta
    31561 aaatatagtt ttttctaact caaaagtgtt ttccatggta gaaattactt taattcatct
    31621 gccatttact ttttatctta tttaataatt actattactt gaatatttac ttctttaagt
    31681 aaatttcata gttaacaaag ctaaaactat tattatagat gttaaaatac aaaattgtaa
    31741 gtattgttat aaatatgctt acagctacaa atatacatga tatattaaaa agaagctgta
    31801 aattattatc atacatacaa gcaactacgc ctctattaat ccatgttaat ttttattatt
    31861 taatacaagg agttccatga gacatacata tccattcata ttttaaatta tccaattctc
    31921 ttatagattt catcatcttt ttataatccc aattccatgg attaggataa ggaactatat
    31981 ttccattctt atttttgact aaatcacctg caaataatac atcttcaaaa atcatgcaga
    32041 catgccctgg agtatgacca ggagtatgga taatttttat attcccaatc tgcatattct
    32101 ctccataagg ttcaacatcc ttaatgagcc ttctggaaat tgcctttcca ataaacttct
    32161 taaacccagg tctatccttc tctcctataa taaaaggtat atcctctaca tgagcccata
    32221 cttttgctcc tgttttttct ttcaataatt taatattaga tatatggtca acatcatgat
    32281 gagttaataa aatatgctta atatctgtaa gtttaatgcc aagtgttttt aattctttaa
    32341 ttatattttc ccccataaaa ggaagacctg tgtctataag aataatttct ttatcaaaca
    32401 caataaaaca atttgagcca cgagtactat ctaacattaa tacattttct tttatcttca
    32461 taaataaatt ccccttattt ggtattttac ctatataatt aattaataaa gttataaata
    32521 gttataatac ttgatattaa ttttattttt tattaaagta tactataggt atacaaatat
    32581 tatatttaca taaatatacc atcagtatac ttttttatca atagaaagga ataatttata
    32641 tgtcagaatt atcaaaaaga gataaagaaa aaatacaaag agaaaatgag attattgata
    32701 aggcagaaaa attattttgt cttaatggat ttgataatac aactatgaat gaattagcaa
    32761 aagaagttga atatactaaa cgcaccatat acaagtactt ttcatgtaaa gaagatttat
    32821 tctttgctgt tgtcttaaga ggatataaaa gactttggga taatgttaaa atagaaagtg
    32881 caaaaggcaa aacagggttt gaaaaaataa aactttcata ctttgctttt cataaatttt
    32941 actctgtaga accttctcta ttatgcctta tgggaatgat tggtattgta aactctgaaa
    33001 aatcggatac tgatatgctg tttaaagaaa agtttttttc ttttaacaaa tttatgtttg
    33061 atgaaataca aggaatgttt gaaattggaa aaaatgatag aagtattagg catgatattg
    33121 aaatacctac tcttatgtat tcatcaatat ttacacttac aggatttttt aatttactat
    33181 ctgtaacagg aaaatcatac ctgaacaact ttaatataga tgaggaaaaa tttattgaaa
    33241 caactcttgc tcttttaata gattcaatta aagcataaac ctaagtttat aaattaaagt
    33301 ttatatactt aaatgataat tttttctatc tctaatataa aaaatattaa acataaaact
    33361 aataacttag ttaatggaat aactaaatta ctgaaaggat taaaagtaaa tggctaaaat
    33421 acttctttta gaagatgatg atacaattac atttggaata aaaacttccc ttgaaaagaa
    33481 aaatcacact gtatgttgtt ataatacgat tgctgaagct aaaaaaaatt ttgataaaac
    33541 tattgattta attctgcttg atttaaatct acctgatggt attggatacg agttttgcca
    33601 atatgttaaa agtatagaag atactccagt gatatttttg acagtccgtg atgatgaaaa
    33661 agacattata cgtggattag atatgggtgc agatgactat gtggttaaac cgtttttgct
    33721 ctcagtactt caatccagaa ttaatgcagt tcttagaaga actcattcaa atactaacaa
    33781 tactattaca tgtgaaaata taagcttgaa taaggttgaa gtcaaagcat atttagataa
    33841 tgttgaagta cctttgacac caggagaata taaacttctt ctaagtctta tggaaaataa
    33901 aaatagagct atgactcgta caaagttact agaaatgctc tgggatgtag atggtaattt
    33961 cgtaaatgat aacactctta ctgttacaat aaaacgtctt agagaaaaat taaaaaatcc
    34021 accttgtata aaaacattaa gaggcatagg atatagaatg gaggacaact agtgaaaact
    34081 ccaagaaata tcaacagtac agttgttttt ataatattct gcttaattgt aactttttta
    34141 ttgagtgtaa ttctaacaac tataacttct tttaatgaat acaatgtact gtctaaggct
    34201 cttggtgcat catatgagta caatcctaag tctacagaaa gtatactaaa atcactgaaa
    34261 aattctagtg ataaggattt taaaacagga aatgaaattt tatcaaaaca tggatattct
    34321 aaaagtacat tttggagtaa aaactttttt tattttctag tgatatcgtt tggtataatt
    34381 tcaacaatgg ctacagttgt atatataatc aaacatagaa caaataagca aaaactgagt
    34441 agaataaaca atcttactca atacttagaa gaagtgaatt taggaaaaga gtctatactt
    34501 ttacgatgtg aagatgaatt ttctcacctt gaagatgaga tatataaaac agttggggaa
    34561 cttcgttgtt caaaagaatt tgctttaaaa gaaagacaaa ctctttcaga taaccttgca
    34621 gatattgctc atcaacttaa gactccaatt acttctatgt cacttatggc acaattactt
    34681 tcagaaaatt gtccagatga agaaatagat tatattaaca gacttacaaa tcaaatctca
    34741 agacttgaga gactagtttc atctttactt acattatcaa aattggatgc aagtacttta
    34801 atatttgaaa gcaaacttat agatgtacat tctcttctta cttatgcaat tgagcctata
    34861 gaaggttctt taagagaaaa acatcagaca tttactatcg aggcttctcc ttcggtagaa
    34921 tttgaaatcg atattaattg gactttagaa gctcttttaa atattcttaa aaattgtagt
    34981 gagcatatag aagatggtgg atatatagtt gcttattata gtcaaaatcc tctatatgtt
    35041 gagattatca tagaagataa tggtaagggg tttgctcagg aagaacttcc atatattttt
    35101 aatagatttt atcgtggtaa aaatgctagt aaggacagta ttggtatagg gcttgctcta
    35161 tcaaagtcta ttatagaacg tcaaaatggt actatacatg cagaaaattg ccataatggt
    35221 ggtgcaagat tcataattaa attttacaca taaaatgctg gattataggt aaaataccta
    35281 taatccagct atatctatat tctatgttat ctattgtttt agtaatatac ttctatttac
    35341 atttaaggtt ttattaaaca aacaacttaa ctatccctat acttgtaagt agtcttaaat
    35401 cgaaaccttt aaataagttc aaatagattt tgtttatatt gtttcatttt ttatagattc
    35461 tactatattt tcattcttca actgcttgta tcctgtcata tatgatgcta ttacaataaa
    35521 aagtatcaat atagtaaaac ctattattgt agatataggt gcaaatggta aatactctat
    35581 aaaatatatt tcatttatac gtagaaaagc atacactatt cctatttgca caggaatact
    35641 aagtagtaat ggtgtaattc ctaagaataa accttccaaa ataagcatct tttttatgcc
    35701 ttctggagat aatccaacag aacgcaacat agcaaactct tgtcgtctac ttctaatatt
    35761 tcctgacact gtagcaagta catttgataa tccaatcata gccaataaac ctgtaataaa
    35821 gcctactatt aaattcatgg tctttattcc actagccttt tgtttttcac tttctaaaac
    35881 atcctcaata ctataatctc ctgaaccata gtctttatta taaatggact ctaatttttc
    35941 tcttactcta ggaatgtcct cacgattatt tactttaaat actcctatca gcctatttga
    36001 acgtaaccta cttacttcat cataattttt agatatttcc tgcaccatag acattggaac
    36061 tatttgcatt aatgtatact ttgaactagt atctactatt ttaggaagtg tgcttgtaat
    36121 agctcccact ttcatgttgt aagtataatc ccctttatct tcgtcatata ctttttcatt
    36181 taatttaatg ttatctccta ttgaaagatt taaataatct atatatactt tatttctacg
    36241 tgtactacga ttaatatctt cctccttatt atatacaatt gaggttggat tttttgtatc
    36301 ataaaataac tttgggtcta cagaaatttg cctacaatat tctgtaaaac tcttatcatc
    36361 aagcccaatt atatttgaaa ttatacgaaa cttgccatca cgttctatag gagagtactt
    36421 tttagatgaa gctatatttt taaatcctcc atttttcgca agttcttttg aagcatcttt
    36481 ttcagtcaac caagtggaag cagacatttt ttgataatat agtgaacttt ttacaccttc
    36541 tgtattatct aatttttcaa tgaaagcaga ctctacaggt tcactatttt ccaaataaac
    36601 tgctatatct ctttggtcct tataattatc acttccataa acagcttttg ctccttcttg
    36661 atttgcaatt atatgcaaaa aacatgtaag taataaaaaa gataatgtta aagatattgt
    36721 tgcagtacga taagattttt tacgagcacg tagtgcgttt gatgcaagtt ctccttctat
    36781 tccaaatatc tttcctaatg aatatttatg cgactttttg attttaacac tatctccttg
    36841 tcgtattgcc tctataggag atatttttga tacttttcgt gctggtataa gtgcagaaat
    36901 ccagactgtt actattgtaa gtaaaactgc tggcagaaaa gcaggaatac cataagtaaa
    36961 taccacttct ggagcatcag catgataatt acctgaatta atatagacta taagcctatt
    37021 acacaataac catcctaaaa ataaacctat tggtaatggt ataattgtca gtaaaaatcc
    37081 ttcaaacact acagaccttt taatttgttt tggtgatgca ccaacactag ataatatccc
    37141 taactgagta agtctagcat ttgcagacag tgaaaacgcg ttgtaaatca ccattacaaa
    37201 cacggctact gtaaaaattg ctattgtaag atacataata ggagttgaaa attttgatat
    37261 actactcata gatgctttct gttctggtga aaagactaac atctttaaaa gataattact
    37321 attgtattta agattgtatt ttccatattc attagtcttc catcccaatg atttagcaag
    37381 ttttggaagt tccttatacg tgtctcttat atttttaaat cgcaagtaca cagttatact
    37441 atcattaggt tttatacttg ttttatcaag atatccaaga gctgtatatg cagatattac
    37501 tgatgaagta gaaacatcta cctttcctac tattgtcaat gtagcctctg aaattttttt
    37561 aaaactttcc cctttcgatt ttggggctat gggttcaaga ggctttccat ttaggattct
    37621 atctcctatt gggagagtaa ttttatcacc aatttttaca cttggattat tctcaaaata
    37681 ttgttttgat aatgcaattt cattagcatt atttggtcga cgaccctcta ttatagtatc
    37741 cttttctggc atagaattcc aatactctga tgtagcattt ctataaatta tataatctct
    37801 tttctcatca ttaattttgc ctacatacca ttgtcctttt accattacat catcaactga
    37861 agaaaaattt tcaattaatg gtaagtcact tccataagta tagtcaaaca attcaccatg
    37921 ccagttacct tctttctcaa ttgaaagttt tataaaatct gtccacatgg tatacaacag
    37981 tccacacaaa gaagacatca tggttgtagt aagtaatata gctaacatta tagctatact
    38041 actacgttta ttgcgtcgta caaagtctaa ggtgtattct tgaagaatat tcatttcttc
    38101 accacctttt cagagacaat cactccatct tccatagtta caatacgatt tgcctctagt
    38161 gctattttct catcatgagt aataagaagt attgtctgat taaatcgttt atttgataag
    38221 tttaacaagt ctacaatttc ttctgaattt tttctatcaa gattaccagt tggctcatct
    38281 gctaataaaa tagctggtct atagattaaa cttctagcta tagataccct ttgttgttgt
    38341 ccacctgaaa gttgacttgg aagatggttt aatctatcag ataatcccaa tatagataca
    38401 atctcagaga atctatcttc atccaccttt cttttatcaa gtaacatggg taataatata
    38461 ttttttctaa catcaagagt aggtataaga ttataaaatt gataaataag acctactttt
    38521 ctacgtctaa aaactgcaag agcttcttcc tttaaacttg atatttctgt atcttcaaca
    38581 taaatctttc cagatgtagg tctatctact cccccaagca gatgtaacaa tgtagatttg
    38641 ccagaaccag atgctcctac aatggataca aaatcacctt tttgaactga taaatttaca
    38701 ttattaaggg ctgtcactct ggtttgattt gaaccatata tttttgtgag attttcacat
    38761 tttaatattt ccatatacaa tcatctcctt tatggttaaa ttttagcaac ctaaaatgac
    38821 attatagtga catgaataca aatataaatt actattaaaa atattgttta gtttttgcac
    38881 attatttaaa attataatat aaaacaaaaa ctatgcaata tattttattt atacttttaa
    38941 tatattacat agtctttaaa aggtattaac tttaaatcta taggtattca atttaataat
    39001 caatagcaag tattttatgt actaaaggag ttttgctcta tatagattca atttagtaaa
    39061 attatttaat aaatattaca gactataggt aaataatatt tacaaataaa attaagttta
    39121 ttcccttaca ctataatatt tcttaattat attaattgca atttccttta cctttggccc
    39181 tgtaatttct ttattggaat catctgattt aatagcaaaa taataggtgt caccttcacg
    39241 ctctatcata ccaacaaacc atgcatccac acgtttattt ttttcatcaa atcctgttcc
    39301 agtttttcca tatacattta tgtttttatc atttacatct attttcataa tatctcttaa
    39361 aatattaata tgctcttttt taaagtttgt atctccctca aatatttttg ccattgtttg
    39421 cacttgttct tttggagata tttgtaatga agattctaac caaaatccat ttaaatgtcc
    39481 ctttccattt tttaaatctc cttcccattc gctaatatca caattcccat actttaaatc
    39541 atctaaaata ttttggacag atttagcatc aactttatct atcaattttt tgtagtacca
    39601 aacacaagac tccttaaatg catcttctaa actaagattt ttattccaat ttttatttgg
    39661 atactctgta ccatcatatc ccataactga ttcttttgag tttattaccc ctttttctaa
    39721 accaattaaa gttgaaacta ttttaaaagt agaacatggt gaccttcttg tttcaattaa
    39781 ttctttgtta tatatattat attctttatt tttagtatta taaaaaatag ctcctccact
    39841 aataccttca aaacaatcac tatagtcaac catattaatt ttttcttttt tgtttttatt
    39901 attgttttca attttggatt tatttaattc agacttattt aattcagatt ttatataatt
    39961 cttatcagtt ttttgattta tatcgttatg ttttttccct acataataca ttaccataac
    40021 tacaccaacc aataagatag ctatccaaat aaaattcttt tttcttttca taatttatat
    40081 catctcccat atttaaattt ataacctact attaaaatag tatacattat ttgtaatata
    40141 ctccaatcta ggttctactt ataagaaaca agactaaatg aatagctgta tctcttatat
    40201 tttcttcacc tagtacaatt atgttgatta aacctattgc gaagataatt aggtaactat
    40261 taataacatc ctgtcctcct tttaatttgt gatataataa ttgattccac atttaaaact
    40321 tactattgta atatttaaat attacaatag taagttttaa atgtcaagtt actttgggaa
    40381 agttatttta attgtataat tgttattaca tttataaaat atggcatgtt taaaattatt
    40441 ttgctattgg taggattaag ataagcagta ttataaaagc tataaattat aaaatttaat
    40501 atataattta tagcttttac ttttacaaat attgttttta ttgatttatt aatgaatttt
    40561 attgacaggt tatatttata taagtaaaca cttacataat aagtatataa tctacatatc
    40621 tataagttga gtcaattcac cagtatatgt caacttaagt ttatgcatag ctcgtgtaca
    40681 agcaatatat aacaaactgc ggtcataatc actataatat gttttattat ttactgaagg
    40741 tacaataact tcatcaaact ctaaaccttt tgacatttta atagaagtta tggatactcc
    40801 ttttgtaaag ctagaacttt cagaagatat taagtgaaca ctatattctt ctcttaacgc
    40861 atcatataca gctttagcgt cattatctgt ctttaatata ataccaagag tcgcattatc
    40921 actcttttta aattcttcaa tttctatttt tatcttattt atttcatctt gctcgttatt
    40981 acattttaat aaagctggtt cttcaccatg tcgttcaata ggttctaatg aagatatgtc
    41041 ttgaatcttt ttggcgaaat taataatctc aaaagtagaa cggtaactct tattcaacat
    41101 aactagttcc ccatcattat atagctgttt catatcatct agtgtatgag tgtgattagg
    41161 attaaccaat tgtccaaaat ctccaagaat agtcttttta cacttaaaaa gtaagtttat
    41221 tacagcatat tgaataggtg tatagtcctg catttcatca ataacaatat gccttataat
    41281 cttatcttct tgtatacctt catatgcagc atgaatatat ataaatgggt atacatctga
    41341 ccattcaagt gttttctttt ctgccatcac aaacatgttt gatatattca tttgtttaaa
    41401 gaaatcctta tatagtgtaa gagtattttt tattgtcaac attccattca aacttttaag
    41461 tatacttttt acctttggta aatcttcttc cataatatta tctgattcaa atttataatg
    41521 aatgtcttca gctaccttct ctaatctctt cttaactgga tatctgttat atgcctcaaa
    41581 tctactctgt atccagtcac ttttagctgt aaaacttcca aaagtgtagt cttttggaat
    41641 aaaaatctta tttggcattt gttttatata atcatcaata agttttacaa aatcaagtgt
    41701 agatttaaaa cgcactcttt cagaccattt agcatcattt atttctaatg ggtctttctc
    41761 actttcaaaa ttaataactc tatctaattg tacctctgct atattttcaa aacttaattc
    41821 acataatggc tcttctccaa gctcaggaag gacattggaa atatagtctc caaagacttt
    41881 attaggtgat aggataatta cattatttgc tgatatttta tctttaaatc gataaagaag
    41941 aaaagcaatt ctgtgtaatg ctatagatgt tttcccagaa ccagctaccc cttgaataat
    42001 cagtgtatca gctttatcat ttctaataat ttgattttgt tccttttgta ttgttgaaat
    42061 gattgacttc attttttcat ctgaagtgtg actaagttct ttttgaagaa tatcatcttg
    42121 tatattaatg gaactttcta gtgcatattc taattttcca tttttaattt taaattgtcg
    42181 ttttcttgtt atttctccat ccacccatcc tattggagca tcatatccag cttttccgat
    42241 ttcataatca taaaacatac tggcaattgg agaacgccag tcaagtatta taagctcatc
    42301 ttcataatca aatgcaaatc taccaatata atacttagat tcatcatcca tatctttcag
    42361 cctaaaatct attctagcaa agtatggaga atctttgatt ttattaatct tatctcgaac
    42421 ttttaccata aaagccccat agttatctat ttgttttagt ccttgttcat tttgaaacat
    42481 ttcatgtggg tctatttcac cacgattttt taccatatac attttagcgt ccatataatc
    42541 cttatcaagc ttgtcaacaa gattttcagc tttcttaaaa gcattgtcta gcttgttatt
    42601 tatctctatt agatgtgcaa tctcatctgg aaaaaaagtt aataactctg catcatattc
    42661 acacatatta tgtttagaat tagatgcaat aatatcgcaa tttactactt gtttattttc
    42721 agacatttaa atcctccttt gttaattaag tacttacact gaatcattat acttaattgt
    42781 gttttggagt ttttaatcat tcttgctatt taacttaaag gaagaataaa tttttgagta
    42841 ggatatccaa attccacaag caactctgct tctgcaaacc ccaacttctt tatcatatct
    42901 ctatgtcctg tatcagcttt gtcaccctct cgaaaggtag taattgaaat atctgtatct
    42961 atcaagaaat cttcaataac tttcttcaaa aacacttgtg caatgtctga attacgatac
    43021 tgtggatgta ttccaaaaaa atcaatactt ctagtttctc tattaaacac catatttgca
    43081 atagcgacat tattaagttt taatattaaa gctctttctt ctaaaatata ctgttctaat
    43141 tgatatatat attcttcctc ttgcaaattt ggaaatccat ctatgactaa tctcactaaa
    43201 ttcatccata atggtatgtc agacatactt gcaagtttaa tttctttttc caactctagt
    43261 acattctttg aaaataggtt atcttttttc aaaacaaatc ttagctgcaa aggataaaat
    43321 tcttgttctt tcctatattt atttggagat tttttataca tagctttaaa tatagaagtg
    43381 aatgcctgtt gactttcata tccagctatc aatgcaattt caataattgg tttctttgaa
    43441 aataccaata attttgctgc ttctgtcaac tttctccgct ttatgtaatc atgcattgtt
    43501 agaccaacag aagttgtgaa agttctatgc aggtgatatt ttgagtaatg aacagcatta
    43561 gcaactatat ctaaatccag cttttctgat aaatgctcct ctatatagtc aatagcagtt
    43621 atgacattaa ttactttgta agacattgca gcttccctcc ttttatccat gcaacattat
    43681 atcaattatt acttagttat atttaatgaa tcttgctatt ttataaacaa atttgttgtt
    43741 taagttttca attcataaat ttaatatatt actttttact ttctgattaa aaactctaat
    43801 cctttaattt tcaataactt ttcatttagt aaatctaaaa agttatttat tattttcttc
    43861 ttattagatt ccttttatat tccttaatta aatgataaat atttatatta tacgactaaa
    43921 aacagctttt tacaattatt taatatgatt acaaacttac cctatcttaa agtttaatgg
    43981 ggtcctgtta tgaatctttt tattttaatt taagctcttc atcagtttat tttatatatt
    44041 gatgtatttg attccataca aaaaagagtg cttcatgaac taaaaagttc atttttaaac
    44101 actctctttt atgtaaataa atttctattc tattttgaaa tattataatt tgacttataa
    44161 tctattaata ccaaaaataa taaattgtac atctaagaat agattctaat tagttgctca
    44221 gtagtaaaat ctatttttaa ctaatcctgc tttgtatgtt gaacatattc tataattgta
    44281 ccatctggat gtctcaatgt catattatat cctgtaggaa cttttttctt atctcttact
    44341 acaactgctc cattatccaa tagataactt ctccattcat caacagaatc aaccataaaa
    44401 gtagattttg tttctataaa tggtttaaga gcatcatcag aaccagataa tagtaaaaca
    44461 tttcctattt gcgctaattc caacccaact tctttatagg aaaaacgcaa agaacatttt
    44521 tcttttaaaa gattctcata aaaaggtatg gctttttcta tatcttgaat ataaaaacgt
    44581 gttaatatat catatatttt catattttcc ccctatatat ctatataata ttacctctaa
    44641 attataccac tctacaaatt atataacaat aaattaagca tagccttttg agcatcttaa
    44701 gtagacctta acaatatatt ggggttacat tataatacat aaattaaatc taaattacac
    44761 taagttagtt ataaattgat tatctacagt tacattagaa tacataaatt aaatcacctt
    44821 gatattattt aggataaaat ttatgtagta gcagtaaatg ttcttctaat tatcaactaa
    44881 caaacgataa tctttaactt tctatataat gggtaacatc attttcgtaa gatattcact
    44941 agctggacga ttgatatcat ttaaatactg gtaatatata tcgccatgaa gtttatatcc
    45001 attgctattt gcccatgaaa ataagtcttc taaagtaggg tcttgtaatt cataaggtcc
    45061 taaatcaatt gcagttatta ttttctgtgc aggaacaatc ctttgtagaa tctcattttt
    45121 cccatctata taagtggcta caggaaaccc tacttcaaca tccaattttg ctaaatccat
    45181 gttatgaaaa catacaatcg gtgctcctga agataaaatt cctctctcct ccagatattt
    45241 agaaattttt tcaaaacttt gttttgaaaa ttctgaaaaa tctaccataa agtcaattgt
    45301 ttttcgtatt gccaaaaaac agtactcaga ttgttcagct attgttatat tggatattct
    45361 agtcatttta ttcctccatt actttatttt catttctaat ctttttatac caaattatac
    45421 gaaaatttac tgtgtaacta attatttcat atgaatataa aacataacct ccttccattt
    45481 cttatatcga aagtatagca aaaataatct catcattctt gtcacacagt gctcttataa
    45541 tcagaacata cttaaaagac ttgcctaatt tttaggcaag tctaaaagaa atctttttct
    45601 ataaaaaatt tatacaaaca attaaaagat caaaatatag actaatataa aactataaat
    45661 ttactaatct gaacctccca tggctaaagt cacaagatta ctgatttata gaatttcgca
    45721 cactaaaata tgtcttacta attccccaca ggctaccccc ctagttccta cgttcttaca
    45781 taagttatct attatcaaac atcaaaattt aaacaagttt caggttcatc ttctattctt
    45841 gctattttaa acttacatgc aattaatact aaagatacta ttggatttat aatatttaat
    45901 aaagcgtatg gaccatatgt tagtgcagat acacctaatg ttgctgttat atacgccccg
    45961 catgtattcc atggtactaa tggagaggtt aaagttccac tatcttctaa agctctcgac
    46021 aacatcttag gatgtatacc tctcttttta tattccttat tatacattct tcctggtata
    46081 actatagata gatattgttc acctgctatt atattggtaa ttgtacaagt taccatagta
    46141 cataatactg ttccaaatac accctttgct aatcttagta aagaagacgc tactacttca
    46201 agcatacctg ttttttctaa aatacctcca agagataaag cgcatattgt taaggataca
    46261 gtggacatca tattcataat cccaccttta gataataaag catctacctc ttgtatttgt
    46321 gttgacgaaa catatccatt ttgtgctgca tctaatatcg tattcataga ttctccttga
    46381 aaaactactg caaacaatac tcccaataca gcacctacta taagccctgg tatagcagga
    46441 actttaaata caactaatcc aattactatt gctggagcta ataataatac tggtgataaa
    46501 gtattaaatg tagaatctaa tgtagaccta attaattcta tttgttttat atctagtgct
    46561 tgacctgaat acttcattcc aattacacca taaattacta aacaaattaa taatgatggt
    46621 atagtcgaat atagcatata ttttatatgt gtaaacaaat ctgttcctgc cattgctgga
    46681 gctaagttag tcgtttcaga taaaggtgat agtttatctc caaagtaagc tccagatatt
    46741 atagaaccta cgattaatcc aattggcata cctaaacttt gaccaattcc taaaagagct
    46801 actcctactg tacccattgt gctccaagat gaacctgtcg caagagatac tattgcacag
    46861 actaatgttg atgctactaa aaaaatattt ggtgataaaa tttttagtcc ccagtaaatc
    46921 atacatggaa ctactccact tactatccaa gttcctataa gtacgcctat tataattatg
    46981 attaagattg cttgcattgc catctttata ctattaaaca tacttaattc taactctttc
    47041 catttaaatc caagtctata tacagccaca agtcctgcta ctgctgctgc tcctattagt
    47101 ggtacatgag gtgatgaacc atacactaat actcctagac ttaaaaataa tatcaaacaa
    47161 gtaattggta tcattgcatc aaacagactt gcttttctac attctcgctc tttcataaaa
    47221 tagtttcctc ctaattattt aaacactaca ctataatttt ttttgaaaca tatttgctcg
    47281 tactagatga catgataccc ccataagtta ataaaaattc taaattgtca cctaatttat
    47341 aatcatattt tgtgttactt acatctagta tcatgtggtc tgaacttgcc cctaatattt
    47401 ttatatcagt gtctattgga attaaagagt caatatttat atcttgttta cctatagcta
    47461 tgattgccct ttttaagatt cccttatctt cataaacagg tttatttcta aaggcatcaa
    47521 ctcctatttc tccaatagga actgatggtt tttctttaca ttcaactact tggcatatta
    47581 atttaaatgc atcttgatat gttccattta tattttcacc gtatgccgtt tctctaccaa
    47641 gtagaatgga ctcgcctatt ctcaaattag taataccttc tggcatatta ttatttatca
    47701 acagatgaat agaacttgaa ttacctccag atactatttc tagatttatt ccaaattttt
    47761 cttccattct ttttgctata cttaccagtc tgcctatatt ttccctagat ggtataatag
    47821 ctccataaca ggttaagttt gtagctatac caattatttc aatatttttt aatcttacta
    47881 tctctcttac attattaaaa aagtcttctt cataaaagta tccttctcgt aaatcgccta
    47941 agtcaaacat aagaactatc ttatgaataa tatttttact ttcacataat tcatttaatt
    48001 tctttattgt tcctaattct gagttaaaac taatatcgca ataattgata acttcttcta
    48061 attcacttaa cattgggatt ctaatcaata tcttaggtag atttatatct tgtaaatttt
    48121 ttaagttttg tattcttgaa tctgctatat ggtctattcc ttcactacat atttcttcta
    48181 ctatttcttt ttgtgcacaa aatgatttag taacaaaaga tatcttaata tttctttcat
    48241 gacacatctg cgaaattaat tttgcattat gctttaactt ttctatatct atttctaacc
    48301 taggatacat aatctttcct cctcaaaatt caaacttttt aacaggagct taagagatgc
    48361 ttcttcatat tttttagata aaacacccat agatgccata atatagtcat tatctattaa
    48421 tatctttgtt ttttcctttg gaaatagtaa ttcattattt ttattgtatt tgagcatatt
    48481 atctaatatt tcaattctac tagggagcct agtaagtgct ccccctgtac caactatata
    48541 tcttacttct gttaaatctt tcccttctgc aattttgact tttccagttg ttccatagat
    48601 atttcttatt tttcctgaat gtcttagcat agctttaaca acagcttctt ttgtcaacct
    48661 ctcaacaaat aatatttctt cttttgattt tggtattgga ggataattct ctattactgc
    48721 atcaatatct atagatagtt cactttgtaa gttttcttta cctataactt ctactatatt
    48781 cttcatattt acatatacac ctaaatcccc ctcaacactt ctctttgcag taggttcagg
    48841 attaaccaaa attttattaa tatagtcact tccatctgta acagaatgta catcagtagt
    48901 tgctccacct acatccagag ttaataaatc tccaatattt ttatataaaa gtttagaagc
    48961 ttccattaca gctcctgggg ttggagtaat attttcatta accatttctt taatgtattt
    49021 cattcctggt gctgtagtta tgtgttcttc aaatacactt tgaatgattc ttcttgtagg
    49081 ttctatattc aataaatcta ttttagggta tacattttca gttatataaa gcttataatt
    49141 agtatcttca aatattaacc ttatttcctc ttgattttca acattaccag catatataac
    49201 tggtatgcct agattcatag aagctatcat ttctgcatta taaatagctg tatctctttc
    49261 tccataatcg actccaccag ctattaaaat tatgtttggg tttatttctt ttattttatt
    49321 taaatcagtt cttttaattc tacctgatgt tatttgacga ataacagctc cagcccctaa
    49381 agctgcttct ttagctgctt ttactgtcat atcatagact aatccatgaa cagtcatttt
    49441 taatccacca gctgcactag aagttgcaaa catatcatta tactctatat catctacaga
    49501 taatttatta gctaaatctt taatagcacc tgataagcca tttcttacat cgccaccttc
    49561 aaacactgtt gttggagctt gaccttgacc caaaaatata ggattgttag tattaatatc
    49621 gtggaaagca tttaccactg tagtagtact tccaatttca gctaccaaca catctatttt
    49681 taaagaaact ttgctatttt ccattattta ttactcattt ctcttctttt ttcaactaag
    49741 aaagtggcta catgtatgcc tttgctgttt cttccaaatc cagcatctat gccttgttca
    49801 acagctattt caggtgttac ttgtgttcct ccacacgcaa tcattacttt atctcttatt
    49861 cctttttcta cacaataatc gtgtaatttt ttcatgtttt tatagtgaat atcatcatga
    49921 cttattattg tagatgcaag tattgcatct gcattcagtt caatcgctgc atctaccaat
    49981 ttttctacag gtacagaagt ccctagatag tggcattcta tgccatattt ttcaatacct
    50041 ccatgtttta tatctattat ttctcttaaa ccaactgaat gttcatcttc tccaaccgta
    50101 gctgaaacta ttttcatagg tttttcttct atatctgctc ttatttcttc atcagttagt
    50161 accttaggtt cttctggtat tactaaattg tttaaatcta tatcaaacgg aactcttcct
    50221 ttcacttcta ttctagtccc ttcagattca tgcataactt ctctacttat gacctcaatt
    50281 tcttgtaagt tcattttttt gacaaattcc aaagctgcaa actctgctgt tcttttatca
    50341 gtaggaagca tcattgttat cattacaatt ccatctgcac accattccat ttcaggctta
    50401 attttagttc catttctgta ctcatatgat tcttttagtc tattttctac attatcaaaa
    50461 tcgtcaagct catcaatata tattattttg tctggatttt caaatgtaca tccatctatt
    50521 aacattgatg gattatctat agcattttca tcatattgag ctacattatt gtatccaaag
    50581 tgagcagtta caggtgctaa ataatcttct tctctttcat aaacagtacc ttcaccaact
    50641 ccacctttta tttttctaga tattccatca ccatttcttt ctggataatt tccagaatca
    50701 acaaaaaatc cttgttccac agattcaaaa tatccaccaa cttcagatat ttcttccata
    50761 tataatacag ctctttcttt aagttctctt gctttgtctc ttaattcacc gacatcttta
    50821 agttctatca tatccataag cccatccata ccaactaaag cttgctttgc tgtatcacat
    50881 gcttctatat tgtatatatg ccaaggtaca tttctacctt catcaggtgt tatagttgat
    50941 tgtatgtcag ctctagttaa tactgatgtt aataggttta atacatgagt aactgttgct
    51001 tctctagttg atgattccat atatttagta ttcatttgag ctctcatctt ataatcacta
    51061 aataactctc taagtgcaac agcgtaaggt aagtctattt ttaaacatgg tgctggaggt
    51121 gctgttggtg gaactgttga taagcatata ttacttttat ctatacctat tttttctgag
    51181 aatatagagt ttaaagcgtg ttgaaccata agttcaggca ttaccttcca tgcttctcta
    51241 gcagtagcat tagcattatg tgctccatca atttgagcta tattggcaaa agccattatt
    51301 ttctttgcct cacaagcatc tacaaaagac cttaccatgt ttatattcct atacagaaca
    51361 ttatattgtg ggtcttgatg tgctccattg actccttcct cagcaaacat tactgctact
    51421 tcaggaccag caacaccact tacatatgaa tggtaattaa taggtctacc aacttcttct
    51481 tctataaaat caagagcctt cctttgagct cttacttgtt ttcttgttat tggaactcca
    51541 cctatacctt gtggagttcc ttctataagc ccatcaaaat gtgattgtcc agcagttctg
    51601 ataaccatta gatggtcagc tccatgatga gctgccattc tcattcttct tatatcatcc
    51661 tcaaatctac cagaagctat ttcagtagta ataactggac ttggttgagg gtctatatta
    51721 ttgaaatact tagatgatgg tagccctaca ctcttcttta aaggttttgt acagtcttta
    51781 tatttaaaag gtcccatttc aagattttcc aagtgttctc tccaaaccca acctcttcgt
    51841 tttggtttat atttatccaa atcttttaat atatagtcta tatccaattt tttattttcc
    51901 tttaacatga ttctacccct tctctaaata aacatgtaac ttcatcccaa tattcaccct
    51961 taactaataa caaacctgct tctctaaccg ttatattttt agatttagcc aatttataaa
    52021 ctacatgccc tgctccttta cctataagac ctctttccat aaccccttct aaaataggtt
    52081 ttacttcaag agaagaaaat cccattctca acaagacaga cctttctatt gatggtgttg
    52141 tattcttttt accaagttct atcattggtt ctactatctg ggtagctaaa ctccaaaacc
    52201 tttcttttaa ctcatcatca ctcagttctt gaagatgttt tcttctaact tcaaaatcat
    52261 cctctctttt tttcatgaac attcctccat tcgtattgat ttaatcgaat tttctgaatt
    52321 tttattttat attaaattaa aaaacaataa ttactataaa ttatttaata catcaacaac
    52381 aaaatctctt gaacttttta cttcttccat taaaaattct atatctcgat tacttagctt
    52441 atcaatatta tcaatgtgat tattagatat acaatttttt ataaatgact ttcttatttt
    52501 attcatatca atatcaacac atttcaataa ttctggtctt tctggtaata ttaagtttac
    52561 tcctgcaatt tcttctcttg gatttccaaa ttttatatct attccatttt ctcttgcaaa
    52621 tgtaagttgt ggacatatat gtttacctgc acccgtatat tctgtttctt gtaccactat
    52681 agctttatcc tcatctagct cttgagctaa agagaatgct gctgctaaag atgtatttcc
    52741 tgctggacct ctttctatac cttctagctg tgccaataat tcagttgtat aaaaaacttc
    52801 tccttgtttt actaatacat atctatccat atatctaagt ggtctagctg cagacctagg
    52861 tacatctgac ctatcaggcc atgtacagta tggtatccca aaacctgtat gtcctgttgt
    52921 aaatgatttt ttattaaatt gattatcact agccatgtgt aatcctttta aatctacact
    52981 tgctcctact actttagtat taatagaacc agcttttatc aatcctcttg cagttccagt
    53041 aagattacca ccacctgcat ttgtacaaac aactatatca gggtcttttt tatacttttc
    53101 tctaaattgg atagctaact cataacctaa agtttctaca cctgcaattc caaatggtga
    53161 atataatgat gcgttaaaat agcctgtttc ttctaataaa actaagaacg tataaaataa
    53221 ctctggtcca acagttaact gaacaacttc tgctccatat gcctcacatt ttcgcgcttt
    53281 ttctatgatt tcaggttgac ctacaccatt agaatcataa cattcttgaa ctattataca
    53341 ttttaatccc tgcattgccg cttgtgatgc tacagctgca ccataattac cactggtagc
    53401 tgctattaca cctttatatc ccatttgttt tgcatgatat actgcagtag ctgctcttct
    53461 tgctttaaaa ctaccagatg cattcattgc ttcatctttt acaaatattc tagctccttt
    53521 accttcttta gcacattttc tagctaattt agtcaaattt ttaagctcta ttagaggagt
    53581 atttccaaca gcatactgtg attgaattgc ttcaatatct tgtaatgtat atcctgtttc
    53641 actcatcatt ttctcataat caaaccctat tccctcttgt tcaaaagaag aataatccaa
    53701 tccgattgca tttttcatta tttcgttatt tcttcccata acagcttgat aactcatatc
    53761 tttcattgat gttgaattat tcattatata cacctccaaa taatatttct ttagcttgga
    53821 ttcctatttg gagtaactct ggtatacatt taccataatc atgagtataa tatggattta
    53881 ctttaagtaa attacctttt acaagtctac ctgtaattgt tttaacttct actaagtcgc
    53941 ctatagaagc atcacttttt ataaaacctt taacccacat ttctaaggat actttcttag
    54001 tatcctctgg aacttgtgga gctctttctt ctggagtcaa tactatattg tgtataataa
    54061 cccaatcatt aattttagca tccatttttt catcccctta ttaattgact attgccttac
    54121 taattaattt actgttattt taaattaaac attattttac caattagcta actgttatct
    54181 tactaattag ctagttgcta tcttactaat tagttagctg ttatcttact aattagcctt
    54241 tgattcttct tccaattcaa cttctatctg atttcttata tctcccatta ttgctctagg
    54301 tactggtata tccaacatag ttttaagacc tggtctagca tttattatta atggaataga
    54361 gtttactatc attgcataag tacctactcc tccaggtatt tcaggattta tttgtaaatc
    54421 aatgtttggt atacctttta ttgatacata gtctcctgtt ttaatacctt ctgcttctgg
    54481 tattatctgt tgtggatgct ccatttcaat taaaacttct ccatttacat atccatatcc
    54541 acattgtcta caaccagcaa catttccagc caatgcctct ccgtacttag attttctatc
    54601 tactgtagtc attattggct cttttgtttg ttctatctta tctaatttcc aacctaatcc
    54661 atcagctatc atatttattg attctacaaa acctacatga cctgctatag tcttatcttc
    54721 tacacctttt ataaattctt cccttgttac tccaacacct tgttccacca taacagactt
    54781 tccaaatgga gataaatcat ttactctctt agcttttata ctagtaactt cttcacaagt
    54841 acctgaaagt gccaatacta gtaaatctaa tacaaatcct ggatttattc ctgttccaag
    54901 tatacttact ccattttcct ttgcaacttc atccattttt ttagctaaat ctgcatcatc
    54961 agcctgtgga tatgccattt gttctgctgt tgatataaca tttatttttc tatttaataa
    55021 gaaaattatt ttatcaaaag cctttttagt aaatgaatca gttgctaaca aaacaacatc
    55081 tacacttttt tctctaaaaa cttcttcata atttttattg ataataactt ctggtctttc
    55141 tcctctttca attcctaaaa catcatacat acttttccct gaagtacttc tactacaaac
    55201 agatactatt tctatacctt ctttctttag aatcatatta gccataccta ttcccatagc
    55261 tccaaatccc catattccta ctcttacttt tctcatatat acaccctcct aaaaatttat
    55321 atattctcaa taattagtta aagcataaat cgtgccaact ttaaaattaa agtaaatatt
    55381 tattggaacg ttgaaactat aattatttta ttatgtattt tcataaataa aaaataatat
    55441 ttcttatgag aaataaaaaa aagagcaaaa tattttgctc ttttataata attttgctcc
    55501 tctattttgc ttttttattt tactttgatt ttgttttttt atcttgctta tttataatat
    55561 tttgatatta tattttttta ttttatactg taaattttgc ctattcatac ctaaaattga
    55621 tgcagcttta gttatattgt aagatgcctt ttctaatgat tcatatatat acttttcttc
    55681 tatctcactg ataatcttac taagtgtttt gtcctccaaa tcgtttaaag aataattgtt
    55741 actctcttta ttctctttaa gattgtaata gtcgtttaga ttaatcatac ttgtttctat
    55801 ttgtacctca tcttccatca tactcatagt acaataaatt atgttttcta gctctcttat
    55861 gttaccttgc caatcgtaat tttttaaaat tttaatagct tcatctgaaa ttcctaccac
    55921 ttttttattt aactttttat tatactttga aataaatttt ttgcacaata gaggtatgtc
    55981 ctcttttcta tctctaagag gaggaatttt tatatgaatt atgttaagcc tataatataa
    56041 atcttttcgc attttatgct cgtttaaaat tacctttgga ctttcatttg tcgttgcaat
    56101 aattcttaca tctataggta tatccttagt tcctccaacc cttcttacat aaccttcttg
    56161 taaaaccctt aatagtttag cctgtaacat aataggcatg gaatttatct catccaataa
    56221 caatgtccct ttgttagctt gttcaaataa gcctggccta tctattgctc ctgtaaatcc
    56281 tcccttgcta gttccaaaaa gaataccttc gaatagtgat tccggcaaag ctgcacaatt
    56341 ttgtgctata aatggatagt ttctcctatt acttccatag tgaatggact ggctaaataa
    56401 ctctttaccc gttccagttt caccgtatat aaatactgaa gcatcagact tgcaagcttt
    56461 cttagatttt tctattgctt ctttaatcaa attactttcc cctaaaatat catcaaattc
    56521 ataacccttt ttttgtctac tactaacttt attgactaaa ttttttttat aatttctatt
    56581 tagtaaattt tctatcgttg tcatattctt tgatatttca agtgccccta caaactcgcc
    56641 tttaatatca attggtattg tagtattaat tgctgttatc tcttttccat ttttatccag
    56701 atatttttga atattgtctt tgataacttc ccttttttcc aaaacttcta atagtgtact
    56761 cctgtttatt ttcattttgt tgactatatc aaaaaatgaa ttggttaaaa tatcgtgtct
    56821 gttcattttt tccatttttt gtacagaatt attgtagatt atagttttcc cgtctttatt
    56881 aacaaaatgt accccttcat caatattttc caatatttca ttcattattt taaaaaatat
    56941 ctcttggttc aactatatca ccccagtacc taaatatata aaaacccaaa aaattaataa
    57001 aatgttgcta ttgtatttat cttatcatat atttatgata ttttttatgt acattatatt
    57061 aatatatttt taagtatatt taaaatttta tttatatatc tttcattatg gttatataca
    57121 atatttgaat tgtcattaaa tatgccaata gttttatata ttattgattt tattaaaaaa
    57181 agagatatac aaactaataa gttgtaatct ctcaaatata aaaaaacaat aaattagctc
    57241 attggatttt ttagtccata atataattat agattattca ccaaacaatc tatagaaatt
    57301 gtggtattaa tgtttaaata accaactttt tctaaaataa cctttatagg aatatatgag
    57361 ttcataagta aaggtagcga aataagaaac cagtttggta tgtaaaatct agatttttaa
    57421 ttaaattatt aagattatat attatagtat caaaaataga aaattaaaat
//
LOCUS       DAEPUT010000014        57225 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.014, whole genome shotgun sequence.
ACCESSION   DAEPUT010000014 DAEPUT010000000
VERSION     DAEPUT010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57225
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.014"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(112..1992)
                     /locus_tag="KRL22_001003"
     CDS             complement(112..1992)
                     /locus_tag="KRL22_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HBH1271517.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTSDKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGADRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASIKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVVVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASQAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIVNRDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            complement(2202..8150)
                     /locus_tag="KRL22_001004"
     CDS             complement(2202..8150)
                     /locus_tag="KRL22_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HBH1271518.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENVSYYNIVFNNLPVGKYNVEVSGAGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNNKDENINQTDNNSNNKDENNDKQQENSDK
                     QEANSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSRSALETYADV
                     QNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEMNIPKI
                     NKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTIEVRDI
                     EAYGLYRVSIQSLNGDWSSDYKDATPENLDGVPENVDSNYKPIQFSPDSILEFQVVPD
                     TKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIRGTSSK
                     IEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKENGGFGI
                     PTNHIVDVTYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRGPIITF
                     DKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNNNKYVM
                     VRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVELKEDVT
                     QEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQEINKL
                     GKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYTQYYGE
                     SGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVAGATKI
                     PHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSYGYSEK
                     TGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMDLVYSE
                     RGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHVGVEYG
                     SVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLALLAQT
                     FDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGSMLKNN
                     SDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFKAWGVE
                     ITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDGIQSGS
                     LVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKGNSKAK
                     FTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITNTVSDG
                     DVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEENPYII
                     VDMKETLPIVGLKYTKPEAEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSNDKKNWE
                     DVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIEVAELD
                     IIGPPGDNIEIGTMNNADETRTNGIGKLAEDYVYQSDDSNTSEDETGKIPAGSIVITG
                     EYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKENFDSLS
                     DKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKARKATRN
                     SIDISNKKVITVSNKVKGNIVRDK"
     regulatory      complement(8274..8359)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(8531..9934)
                     /locus_tag="KRL22_001005"
     CDS             complement(8531..9934)
                     /locus_tag="KRL22_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HBH1271519.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     gene            complement(10396..12291)
                     /locus_tag="KRL22_001006"
     CDS             complement(10396..12291)
                     /locus_tag="KRL22_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HBH1271520.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            complement(12916..13059)
                     /gene="scfA"
                     /locus_tag="KRL22_001007"
     CDS             complement(12916..13059)
                     /gene="scfA"
                     /locus_tag="KRL22_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HBH1271521.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(13125..13487)
                     /locus_tag="KRL22_001008"
     CDS             complement(13125..13487)
                     /locus_tag="KRL22_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HBH1271522.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(13545..13838)
                     /gene="yajC"
                     /locus_tag="KRL22_001009"
     CDS             complement(13545..13838)
                     /gene="yajC"
                     /locus_tag="KRL22_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBH1271523.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(13972..15093)
                     /gene="tgt"
                     /locus_tag="KRL22_001010"
     CDS             complement(13972..15093)
                     /gene="tgt"
                     /locus_tag="KRL22_001010"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBH1271524.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(15172..15657)
                     /locus_tag="KRL22_001011"
     CDS             complement(15172..15657)
                     /locus_tag="KRL22_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271525.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            complement(15669..16694)
                     /gene="queA"
                     /locus_tag="KRL22_001012"
     CDS             complement(15669..16694)
                     /gene="queA"
                     /locus_tag="KRL22_001012"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBH1271526.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(17012..18031)
                     /gene="ruvB"
                     /locus_tag="KRL22_001013"
     CDS             complement(17012..18031)
                     /gene="ruvB"
                     /locus_tag="KRL22_001013"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBH1271527.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(18138..18740)
                     /gene="ruvA"
                     /locus_tag="KRL22_001014"
     CDS             complement(18138..18740)
                     /gene="ruvA"
                     /locus_tag="KRL22_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBH1271528.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(18733..19242)
                     /gene="ruvC"
                     /locus_tag="KRL22_001015"
     CDS             complement(18733..19242)
                     /gene="ruvC"
                     /locus_tag="KRL22_001015"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBH1271529.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTHAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(19554..20183)
                     /locus_tag="KRL22_001016"
     CDS             complement(19554..20183)
                     /locus_tag="KRL22_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271530.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            20386..20709
                     /locus_tag="KRL22_001017"
     CDS             20386..20709
                     /locus_tag="KRL22_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH1271531.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            20977..21831
                     /locus_tag="KRL22_001018"
     CDS             20977..21831
                     /locus_tag="KRL22_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271532.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(22017..23453)
                     /locus_tag="KRL22_001019"
     CDS             complement(22017..23453)
                     /locus_tag="KRL22_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBH1271533.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNELLADELKYLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTKGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKVLGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(23525..24907)
                     /locus_tag="KRL22_001020"
     CDS             complement(23525..24907)
                     /locus_tag="KRL22_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1271534.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(25043..25948)
                     /gene="garR"
                     /locus_tag="KRL22_001021"
     CDS             complement(25043..25948)
                     /gene="garR"
                     /locus_tag="KRL22_001021"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBH1271535.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            26344..27015
                     /locus_tag="KRL22_001022"
     CDS             26344..27015
                     /locus_tag="KRL22_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1271536.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            27118..27666
                     /locus_tag="KRL22_001023"
     CDS             27118..27666
                     /locus_tag="KRL22_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271537.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            27928..28236
                     /locus_tag="KRL22_001024"
     CDS             27928..28236
                     /locus_tag="KRL22_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271538.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(28398..30188)
                     /locus_tag="KRL22_001025"
     CDS             complement(28398..30188)
                     /locus_tag="KRL22_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271539.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(30188..31915)
                     /locus_tag="KRL22_001026"
     CDS             complement(30188..31915)
                     /locus_tag="KRL22_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271540.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(32160..32426)
                     /locus_tag="KRL22_001027"
     CDS             complement(32160..32426)
                     /locus_tag="KRL22_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HBH1271541.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            32723..33835
                     /locus_tag="KRL22_001028"
     CDS             32723..33835
                     /locus_tag="KRL22_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH1271542.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            complement(34200..34709)
                     /locus_tag="KRL22_001029"
     CDS             complement(34200..34709)
                     /locus_tag="KRL22_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBH1271543.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(34711..35358)
                     /locus_tag="KRL22_001030"
     CDS             complement(34711..35358)
                     /locus_tag="KRL22_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271544.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(35372..36544)
                     /locus_tag="KRL22_001031"
     CDS             complement(35372..36544)
                     /locus_tag="KRL22_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1271545.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNIESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            36812..38188
                     /locus_tag="KRL22_001032"
     CDS             36812..38188
                     /locus_tag="KRL22_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271546.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNELTLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            complement(38439..38798)
                     /locus_tag="KRL22_001033"
                     /pseudo
     CDS             complement(38439..38798)
                     /locus_tag="KRL22_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(39125..39655)
                     /locus_tag="KRL22_001034"
     CDS             complement(39125..39655)
                     /locus_tag="KRL22_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1271547.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            complement(39743..40837)
                     /locus_tag="KRL22_001035"
     CDS             complement(39743..40837)
                     /locus_tag="KRL22_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HBH1271548.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMKMGITSHDEIKKIMNDGVKDYITNMTKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFTSEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            complement(40839..41285)
                     /locus_tag="KRL22_001036"
     CDS             complement(40839..41285)
                     /locus_tag="KRL22_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1271549.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            41591..42781
                     /locus_tag="KRL22_001037"
     CDS             41591..42781
                     /locus_tag="KRL22_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1271550.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            42951..43913
                     /locus_tag="KRL22_001038"
     CDS             42951..43913
                     /locus_tag="KRL22_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH1271551.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(44035..44697)
                     /gene="zmp1"
                     /locus_tag="KRL22_001039"
     CDS             complement(44035..44697)
                     /gene="zmp1"
                     /locus_tag="KRL22_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HBH1271552.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     regulatory      complement(44797..44882)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(45068..47986)
                     /locus_tag="KRL22_001040"
     CDS             complement(45068..47986)
                     /locus_tag="KRL22_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH1271553.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEVPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSKIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSVLEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDANFTNVKVGETIRNVAQINGSSPPGVETTKQGYTFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSVKKPGTYYLVEIMAPSGY
                     EKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPAPPNTDEPIVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPVPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      complement(48104..48189)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(48316..49494)
                     /locus_tag="KRL22_001041"
     CDS             complement(48316..49494)
                     /locus_tag="KRL22_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH1271554.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     gene            49869..50054
                     /locus_tag="KRL22_001042"
     CDS             49869..50054
                     /locus_tag="KRL22_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH1271555.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKEAYKILQKLDIDFECVDTYEAIT
                     MEDCVQINKKLNMKMVI"
     gene            complement(50119..52893)
                     /locus_tag="KRL22_001043"
     CDS             complement(50119..52893)
                     /locus_tag="KRL22_001043"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH1271556.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEENLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(53065..54321)
                     /locus_tag="KRL22_001044"
     CDS             complement(53065..54321)
                     /locus_tag="KRL22_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH1271557.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            complement(54393..55895)
                     /locus_tag="KRL22_001045"
     CDS             complement(54393..55895)
                     /locus_tag="KRL22_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH1271558.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFTFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            complement(55986..57176)
                     /locus_tag="KRL22_001046"
     CDS             complement(55986..57176)
                     /locus_tag="KRL22_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1271559.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIAHGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
BASE COUNT        18149 a         9952 c         6641 g        22483 t
ORIGIN      
        1 attttaacct caatattatt agattgttaa gataatgaaa ataaaataag aatgcattta
       61 aatatataac tttatatcta aatacattct tattttctat ttacttaata tttatttttc
      121 aattaaactc ttaatcttgt ctattacaga tgaggctatt cctccaccta cttcaaacaa
      181 ctttgatgaa tttttacctt ttaatgacga ttcttgtgat ttatctaacg tatttgtagc
      241 aagtataact ggtgaattgt ttttagctgc taatggtcca actgctaaag catctataag
      301 tttatcttga tttgcaacta caactccatc tagcttagat tgagagtaga atttatctat
      361 tactttggca ttcgtctctt gtctagtttg acctgccacc ctattgtttg atatatctct
      421 gtttactatt tttccaactt gttcaatagc cttgttagat attttttcta ctccaccaat
      481 aaaatatata tttgacacct tatttgattt aataaattgt tcagcttcat tatctacacc
      541 atctttttgt gtaagtacta ttggagtttt ttctttacca gcctgtgatg ctattgataa
      601 tgaatcagct tctccatttc ctgctcctat atacaacttg cttacattat tcgtcttatc
      661 tatttctttt gctatattaa tagaagtttg atatcttgta tctccaccta ttctttgtac
      721 tgatattttt gaatttacag ctttgatagc ttcaacaact gaatttggca ttgagttgtt
      781 tccacctata acaactactt ttgatggatt tagccttttc aattcttcta cagttttttg
      841 aggaagcttt tcatttgatg ataaaagaat cggtgagttt tttatactag caagtggtgt
      901 agctgtaagc ccatccacca tacttttatc ttctccattt actattacaa ctgtatctga
      961 ttttgtccaa ccactttgag atattttgat agctgtttca aatctatcag caccttttaa
     1021 ttttttgact gtgacattag atgtagaatc acttgaattt cctcctccag agcttccacc
     1081 actagatgag ccgcctgaat tacttcctcc gccattattt ccaccattgc cattatctgg
     1141 tggtaattca tctggttttg ataattcatt ttcaactatg tattctaaac tttttggaag
     1201 tgtaacttca acatatttgt ttattgtagc ttttcttccc ttagttgttt tttgtgctaa
     1261 tccaagtttt aatattacat ttgaaccact ttcttgtgtt tctttactaa caatagaata
     1321 gtttatccta atattgttta ataaatattc aagtgcttca cttttctcta ccttatactt
     1381 ttcagggtca tttttactag aaccagttcc accaattggt tttacttcac tctcattaat
     1441 aagggtaaat attaatcctt catcagagct tatattttca taatccactg ttttgttgtt
     1501 atatgttaca atttttaaag ctggtttatc acttgttcct tttcctaaaa ctttatagtc
     1561 agcatttgag ttactgccag atttttttac agatattctt cctatattca atctatttcc
     1621 gtctagtaaa tcttcatttg atgtaacgta tatatctaat gtagttgtat tacttgattt
     1681 gttgtattct gctctacagg tagcatttgc atttccactt tttatctgag attttatatt
     1741 atcagaccaa gtaatctttt ctttctgctc attatctact acttcaacct caccttgtac
     1801 ttttatactg gcttgaaatg aatatactat gttttctact gagtccacag atatatctat
     1861 agtatttact ttctcatacg tttttgttcc ttgtaaaact ggagctgcat atgcacatgt
     1921 agcactacca gttacagcta ctgccatagt tgatactgct atagttctta taaaagattt
     1981 tcttttactc attaacaccc gtccttatct atcattaact aagtggataa atttacttat
     2041 ccacctagct tttatattta atttataaat taccctaaat ttatggttac atttatatac
     2101 tttactttta atatctacta ttttaaaact attctagtac ctaatcttat tagatataca
     2161 atgttagtgt tagtattttt gcgtttttag agttccacct actatttatc tctaacaata
     2221 ttacccttta ctttattgct tacagttata accttcttat tactgatatc aatagaattt
     2281 cttgtagctt ttctagcttt actattacta tcagtaagac ttattgtctt taactcatca
     2341 taattcttag ctcctacagg tacatacatt gtatcactta caaatctttg acctactgga
     2401 gtatctcctt gaaggtcatt gtatctatat agttcagcct taaccttatc acttaaagaa
     2461 tcaaagtttt cttttggcat atagtaaacc catgtacctt tactgatttc acctagttca
     2521 cctttttctg gaacttctgc aaataaaagt gcttctccag atatagtctt attgttttta
     2581 tctataagta gtggtaaatt aaatgctgga tttccactgt attcacctgt aataactatt
     2641 gaacctgctg gaatcttacc tgtttcatct tcacttgtgt tagagtcatc actttgatat
     2701 acataatctt ctgctaattt tccaattcca ttagtacgag tttcgtctgc attattcatt
     2761 gtgccaattt ctatattatc acctggaggt cctattatat ctaattctgc aacttctata
     2821 ttagacttat tatttgagat tagttttaca tatctagctt ggtatgtcca aagtttacca
     2881 tctttattaa atgtaactct agcttcatta tcttggtctt ttcctccacc aactaaatcc
     2941 tgtccatatt caaaagttcc ttgacttaca tcttcccagt tctttttatc attacttact
     3001 tgtatcttgt aattagttaa aggattgtat gttgtgctag tattctttct aaagttaaat
     3061 aatcctttta atgagaactt cctagcttct gcctctggtt ttgtatattt tagtcctact
     3121 ataggtaatg tttctttcat gtctactatt atatatggat tttcttctac atttatatca
     3181 gggtcttttt gagggtcttt gttccactct gctttactta ttatctttcc tttatatgta
     3241 gtacttgcat cattatcttt tatattatca atttcaggat tttgtaatgg tccatgtgag
     3301 tcattttcag ttctaacatc accgtcagaa acagtatttg ttatgaatga ccatgctgat
     3361 ttatttattt tcccttcatc tgataatttt acagtgccaa cttcaaattc ttctgttgga
     3421 tttaggtgat aatcatatgc aactacctta tatgtaaatg ctctgttatt aagaggagat
     3481 atattatcag taaatttagc cttactattt ccttttgcat ccacaaatcc aactgttctg
     3541 tattttacct gtgttccatt ttcaccatct aaataatttc catcacttct tattatttcg
     3601 tatcctagta tcttatcttt atccttatct acatctaggt ctatagatat tttattagat
     3661 ttaactagag aaccactttg tattccatca gaaaaactag cacttacttt agtatctttt
     3721 gccatactag ctatattttc atttaaaatc tttcttctag cttcgtcatt tacatattgt
     3781 atctttcttg attctttttc gtagttctta ctatccatta tactgtttaa ttctggtgta
     3841 atttctactc cccatgcctt aaagtaatct cttaaatctt tttcaacaac acttgatgcc
     3901 attgctacta gcatttggtc ttttggtaaa ctattaattg ggtcactact tgaaagtgct
     3961 ctgtattttc ttgaaatctt tgcataaaat gtatcattac ttaaatcagc atctgagtta
     4021 ttctttaaca ttgaacccgt aaaatcatca tcataagcta gatgtaattg ccataacatt
     4081 ccaagccttt caaatacatt gcttggtata cctaagctat ttgaagttac atgctcatat
     4141 atcttatcca ttgttgaacc ttcaagtctt gaatgtgtct tatcatcaaa ggtctgagca
     4201 agtaaagcaa gtacattgtt actagtttcg ctatatgtca tctttccaat atctgtaaca
     4261 tgtcctatct catgacctat tccccatcca aataagtttc ctcctgtagc ttttccacta
     4321 tcatctattt ggaaaggtac tccattcata agccctggaa ctgaaccata ttctactcct
     4381 acatgtaatc cagaagcata cataaatgct ccaataaaca ttctttggta ttttatgttc
     4441 atacgagatt ttggagccat atcattttta gttaagttaa attcattatc atctacagtt
     4501 ccattaccat ctaaatcttg tgttttaaat actcctcttt ctgagtaaac taaatccatt
     4561 atttgttccc atgcaagcat actattatat aatctatcta cttgtgtatt taaatcagca
     4621 tttccttttg atatcccttg atatacagct gttgcaggaa catttaatgt tactttatca
     4681 ctttcaatat ctgtagtgtt taacacacca gttttttctg aatatccata tgaattacca
     4741 acatttgttc ctggataata tggttctcct tttacagcat ctttatattt agctaattct
     4801 tctatatatg cttttatctt tttcttagat tcagaaactc ccgcaggact cttatcattt
     4861 attgttccat ttagattaag atgtggtatc ttagtagctc ctgctacacg tacttttata
     4921 tctcctccac ttggagtatc ttcagcatat cttatgtata aacttcctcc acattctata
     4981 tctaaactat gaagtttgct taattgaatt acattttttc cagtgttaag atttatttct
     5041 ccactcttat atgcaccaga ttctccatag tactgtgtat atatcaactt aggagttttt
     5101 ccacttttac ttccaacata tactgtgatt tcatctcctg ctctagcagc tactcctaat
     5161 gcctgccagt cattttgcat acctaaatta ttggaattta cagtatactg tccgttttta
     5221 tctttatatt ttcctaattt atttatttct tgatttacag tcgttacatc agtaagtgtg
     5281 gctctatcat tatataagtc ttgagctaat tttaattctc tctcaataac tgtcttatat
     5341 ggatgatatt ctccactagc tttatctgga gtatttaatc tatcttttaa ttcagttatt
     5401 ttttcttgag ttacatcttc ttttaattca acttgtaggt catccataaa tagatttctt
     5461 acatcatctt ctatactgtc atactcataa aacttaagtt ctgatatatt agacttatat
     5521 gaataggatg aacaaacact tacttgtatc ttggtagcag ttattggttc ttttaatcta
     5581 accattacat acttattatt atttacaggg tctgtctttg tttcaaaagg aacatccccc
     5641 agattgtgta attgaccatt ttcatcccaa tatcgtacct caaagtcatt tattgtctta
     5701 tcagaaacat caaaacgagg tgtagccata aaagtatcca tagtataaga tttatcaaaa
     5761 gttattattg gtcctctatt cgttccctca gctgcattat atgttgggaa tgtccaatgt
     5821 gttgtaaagt ccccatctac tacattgaat ttatcaaatg gatttttatc actatattca
     5881 cttttgtcat atcctgctgg ataagtaaca tctacaatgt gatttgttgg tattccaaat
     5941 ccaccattct ctttaggagt attaattaat ctatagttag gtgttgttgg tgcatccatg
     6001 ctttcagttg tacctatata tgttttagac attccactag ttcccaagtg gttagtagct
     6061 gtcattctaa cttcatatgt tgtattatcc ttaagacctt ctatctttga acttgtccca
     6121 cgaataagct tatcattgta ttttatccaa gacccattag aacctttttc tttatagtac
     6181 aagtcaaaat ctttagcttg tttatgattt ttccagctta catcaagaga tttaaattta
     6241 cctttaacat ttataccttc tggtggttct ggttttgtgt ctggaacaac ttgaaattct
     6301 aatatactat ctgggctaaa ttgtataggt ttatagtttg aatctacatt ttctggtact
     6361 ccgtctaagt tttctggtgt tgcatcttta taatcactag accaatctcc atttaaagat
     6421 tgtatgctaa ctctatatag tccatatgct tctatatctc taacttctat tgtattttta
     6481 ctagtttgta attttttagt agataatact tttcccttac tatcaatttt gtctagtata
     6541 agttcgtatg ctgatacatt tacttcatta ttccaataaa aagatacttt ttcatttcca
     6601 acagcagtgc tagtcgatat tttatttatt ttaggtatat tcatctctgg ttttggtatt
     6661 tctttatata cattgtttaa aaattcaact tttgatattt ctgcaagatt tctatcgttt
     6721 gctgttgtag ctgttatttt tatagttatc ttttttactg ctacttgttt accaagattt
     6781 attactatat cactattttg aacatctgca tatgtttcta atgctgacct actatatgta
     6841 gatgttgtag agttatcatc tttactgata ttaccctctt cttttggagt atcttcatct
     6901 gaattaggtt tatccattga tgaattttct ttatcattat ttttatcttg attggtatta
     6961 gagtttgctt cttgtttatc gctattttcc tgttgtttat cattattttc atctttatta
     7021 tttgagttat tatcagtctg gtttatattt tcatctttat tatttacttc ttcttgttcg
     7081 ttatttactt cctcttgttg ctcctcatct tttaagtttt tcatatattc tttgttttca
     7141 taaggaatct gttgaacatt accatctttg tcagtaacct caactattcc ttttgctgga
     7201 gcagtacctt ctggagcttt tatattgatg acttccatat taagtgcttc tgataaagct
     7261 atatccatta ctgctggttt ttcctcagat atttcatcat tttttgaaga tattgtaact
     7321 ccattatttt ctccactaaa taaattttct acattaccat taatatctac atcactattt
     7381 ccttttaatt caaccttact tgtatctact ataggattgg tagatactat actttctagg
     7441 ctttttgcat cttcactttg tcctaaattt ttctgtacat aatctaagtc aacaatatct
     7501 acctttccat ctctatttaa atcaaattct cttttatttg aatctatatt ctctaaaacc
     7561 ttattataat cactcttatc tactttaccg tctccattta catcacccat taagaataat
     7621 tcataattta aaggtttatt tttattatct acacttgctc tattgcttaa taagactctt
     7681 tgtgaataac ttgatatatc aatgtcttta atttctttgt tcttaaatcc agctccagag
     7741 acttctacat tgtattttcc aacaggtaaa ttattaaata caatattata atatgataca
     7801 ttctcatctt tattttttat ttcacttcta cttgcagata atttttttat agtatattct
     7861 atattatctg tcccaacatt tactgttcct gaatcttttt ctccaagctt tattattcca
     7921 ctattgttac tatcatcttt taatcgtaac tgcatattag tcatactttc tgactcgcta
     7981 ttttttattg gcagtgaaaa atttaaatct acttcaagac tcccccttaa cttttctgta
     8041 actgattttt caactgccct tagcttcccc tctaatatag gttctgcaaa aacgtttagt
     8101 ggtgcactac acatagatac tgctagtaca caagatattg cctttttcat gaaataacaa
     8161 tcctccctta ataaatatct aatttttcat gaatttaaat actataagtt tcagacaata
     8221 aaaaaagaca ctcaaagaga atcttaatta taaaataaaa agactttact ctttttagca
     8281 actggctgat atggctttaa aagctttaat ccctatagtt ttgcgtcatt agatttccct
     8341 aattttgcca tttaattttc actactttct tacccatttt atactatatt taaacttttt
     8401 aatacaattt ttttacatta aattataaaa aaataacatt tatattaatt tattaatata
     8461 aatgttattt tccattataa tttaattatt tatatagctt ccttacaagc ataattttgt
     8521 gtatattttc ttattcttta tatcttccat aaaattcatg tgtagcatat agattcttat
     8581 ctcctgttat agctatacca aatcccatta tttcataccc tttatgcaac atattagtgc
     8641 cttcttctgg atttgtcttc cactcattaa aaataaagtt tcctatatca tctgcatctc
     8701 tatttgtata tacaggttta tctggaattt tatatttaat tatattttca ccttgaactg
     8761 ctatatatcc aggtttaatc tcactccaat ctaagtattt caaaaaagta gaatatgaat
     8821 tttttccatt tatcgtatga gataaagtct tcttatttgc cattaaatta gaccaatcat
     8881 ttgctagacc ctctaatctg cttgctacag ataacgctct tactccattc tcttttctat
     8941 actgctttgt aagagcatat actttaccct ttattctctc tttaaatgct ctatcatttg
     9001 gattgtaata taacccttgt tgatttggtg aagcttgatt tatacattgc ttgataacgt
     9061 tctgatttat gcctcctagt acagtcaatt tgtctgcacc acttaaaata ctcttgttac
     9121 tgccattttc aactaaaact acaggagcat tttttgctat tgtagaggca gccaaagcgt
     9181 ctgttaattg taagccttta cttagataaa attctttact atttttataa aactcttgta
     9241 taactatctt attagtttca aatctatctg tgccacccaa tctaatagaa tttgtgctct
     9301 taactaattc gtcgctgatt atttcactag aaccaagcgc ataactcttt aagcctgtcg
     9361 tgtcaaatcc cacactattt ccatctgtaa gtattatagg tactccatct ctagcagcta
     9421 ctggtgatgc acttatcgca tctgcttctc ctgtaaatcc attggctata attactttat
     9481 ctattggctt aatttctttg attttttcag ctatttttat acttgtatca aatctatttt
     9541 caccaaagat tctttgtaca accttctttt tggatagtaa ctgattctca acatttttac
     9601 ttattgttga ttctgatcct attatataca cagtctttgc tttgtttaat ctttccatag
     9661 ttgtgtttgg aatctggttt tgttttgtca tcaaaatagg cgcatttaag gctccagcta
     9721 aaccacttgc acttagacca tctgctaagc tattatctga gttgattagt attgctgtat
     9781 tgtagttttg cttatctgct atttttgctg ctgtctcgta tctgtcattc ccttttattt
     9841 gctcaactga tgtcaacgca tttaccatag gagtatttac cattactaaa aatagtgtaa
     9901 gtcctatagc taatatcttt ttactattct tcatattatt ttctaccccc aatgtacttt
     9961 tcatattttt tattagtact catacttatt tttaatcaaa agttacaatt ttgttaccat
    10021 attttatata tgataccata gttatccata caactcaaac aatataccta aagtttttat
    10081 tctctataaa ttcaaaacat tataatttat tttatttaat taagttataa gttcaaaata
    10141 atttatgtta ataagatgtt taatcattat aagaagtatc tttttataat aatttttgca
    10201 atatgaattt ctcaacatta taatcaaaaa ataaaataag gtatctcaat ctaattctaa
    10261 atgagacacc ttatttttat tattttatct tgttatttgt atattttata atatctacac
    10321 tatgtcttac atattaacgc attgtataat catatattat ctaaataaac ttttaatatt
    10381 aattcctata tcttattagt tcttagtaaa taagtttatt ttttctgcta ttttttcaat
    10441 agcgttttta gctattcctt cacctatttg tactaactta gtagcattct taagtcttaa
    10501 ctcaactact tcttcttgtg atttagaaag ttcttctgta gttaatacta ttggagcctt
    10561 tgaactagct gcaagtggtg ctgctgtaag tgcatcaact aattgtccat ttccacctac
    10621 ataaccatct tttgctacat atgctttagt tgcacctgca tagtatttat tgattacttt
    10681 agcattagta tcttttctat tttctccagc taatctttca actttattat ttaaatctat
    10741 atcaactaat ttgtcttcaa cttcttttga tacagaattt tctccaccca ctatttctaa
    10801 ttcttttcct tttaataatt tttcagcatt tgcatctaat tcgttacctg taactattat
    10861 tggagcacca aattgagcag ctctagctga tatactcata gcatcagctt ctccatttcc
    10921 acctactaca aaagcagtct taaatgtatc ttttaattgt tttgctattt ctaaagaagt
    10981 ttcaaatcta tcttctccag aaactctctc aactttactt acacctaatt tagaaagttt
    11041 ttcttcagtt tcttttgata ctttagattc tccacctact atatatattt tcttagaaga
    11101 tagattactt ccaagtactc ttaatatttc agcttctatt tctgatggta gtgaatcttt
    11161 tttagataat aatattggtg catttttttg agaggcaagt ggtgctgatg ctaatccatc
    11221 aactatagca tcttctccaa ctaaaattat agcttctgct tctccatctt tgaatctctc
    11281 tttactaact tctactgctg ttgtaaatct tgaatcacca gataaaactt ctacttttaa
    11341 ttcttttcca tcttttacat cagttaatac tttgtgtaag tctctaacta acttatggtt
    11401 tttacttgaa acacttattg tttctggctt ttcatttgcc ttgcttaaaa ctatatcaaa
    11461 gcttgatttt tctggtttat ctttatcatc actatcttct tgttcttgag taaggattgc
    11521 ttcattttca aatgttaaag catatccatt tttaacttta ttaactattt ctcttcctaa
    11581 tgtagttaat ctaattccat caaataattc ttctgctgat atgtcttgta aatctgcgtt
    11641 tttaactgtt atcgtatgta attcttttga atctatgtca ctataactct tttcataacc
    11701 ttcaaaagta ccttcttctg atgttatcac ttttgagaaa tctaaatgtt ggtctcctac
    11761 atttaatgta ataacatttg ctgaatcttt tgctcttttt acttcaactg tatttgtaga
    11821 ttttatagtt gctgttaact tgttatcaga atcttctgct aaagttgcat tgtaagcatt
    11881 aactgcatct actatttctt gagcagtttt gtagttttca attttatagt caactacttt
    11941 tccacctaac acttgatgtc ctttatcttg aatagtaact tttaaacttt gcccttctgt
    12001 taaagagttt atcttatttt gtaattgagt tgcattagtt aagtttacat tgtctacttt
    12061 tatatcgtaa actctatcat ttacatttgc tcctgctttt gtatcttcaa acttaacttc
    12121 taatgctttt ctaacctctt cgattagttt agcagaatct ttcgcactta ctgtgtaatt
    12181 tttatcaaca ttttctgtca cagtattgtc tgcgaatatt ggtgctgctg cactcataac
    12241 tgtagcacct gccattacta ttgccatact tctctttttg ttgcttaaca tatttatgtc
    12301 ctccgaatat tattttttat tttttatatt cgtatttccc acacataaat aatattatat
    12361 ataatattat ttttcaatat attttatgtg tttacataat ttactaacac aaacactaat
    12421 aatatcttct tgaacccctt ccccctgctt agctctctat aattatgctc aaagatagaa
    12481 atccctattt tatagtgatt ttctactaaa caatcatata ctaacaaaag tattcaaact
    12541 ccatttttat atactactat gcactaattt ttgctttact cttattactt aaatatatat
    12601 cactaaatta atatctatct ccaaatatta aaatatataa catattataa aaatcatcat
    12661 aaattagagt ttaaaattaa aaattattct aatacatgta attgataaaa aataaaatat
    12721 aagagtagct actttaaaat gaatgctctt atatgattag atatttttgc ataattaaac
    12781 gataagaaat caaatttaat tttacataaa tagaatatat ttttatataa taattgaaaa
    12841 taaaagagga tacctcataa tgataaaaga atcactttga gataccctct tacaaacaac
    12901 taaatcaata attttctatc tttcacactc ttgatttgca actgtacaag aagttttaca
    12961 agctgattga caagaagttt gacactctcc acatccacct tttgcagcac tttgctttaa
    13021 agtagcttga gataaagttt ttacatgttt attttccatt ttcaacgcct ccatttctaa
    13081 ttgtttccta ttgattatat cataaaacta ctttaatata aactctattt aaagttgaca
    13141 cccaatacgc ctccaatgcc tcctgctgct gatattaaca ataacttata aatcatccct
    13201 acttcaaata caaacttttc ttgtgctaaa aacacagtca aaaaaataca tactatgtac
    13261 aaaagtccta ctaaaagccc atacataagt cctttttctt tcatgtgttt tgaagtgtaa
    13321 aaccctccta tagctgcaga aatagtagtt ataaatgatg agaccatagt tatattatct
    13381 ccaccaatat ctgtaaatgt caaaaataag ttatacacta ataaaacagc caaagttatt
    13441 atatatgcat atcctagacc tttaaaaata taattagatt ttcccataaa aaaacctcct
    13501 ctcaaattaa tatatattcg agaaaaggct tttaaattac taatttagtc ttcttctatt
    13561 tcttcttttt tagatttaac agttcctata gcccattttt caaatggaac tttagttcta
    13621 tttggtccta attctaatat tacaacatca tcttcaactt tagctacatt agctactatt
    13681 ccacctattg taatgacctt gtctcctaca cttaggctac ttctcatttc ttttaattgt
    13741 ttgtcttttt tcttttgagg tctaatcatt aggaaataaa agattgcgat tactactacc
    13801 catagaccta tactcataat tatttgttgc tgtggcatta atttttcact cctttgtaaa
    13861 ttatactctt ttgtaaatca taataaatgt ttatataaca atttactttc tctatctttg
    13921 agtactattg aatattatat attaaaatga ttataattaa tagtgcaaaa cctatatttc
    13981 atatccatat tttgcaaaaa attcatttct aaaatcaagt aatctatctt ccattatcgc
    14041 ttgtcttatt tgtttcatta aatttaataa aaagtgaaga ttatgagtag ttattaatct
    14101 tgcacccagt atttcatttg cttttataag gtgtcttata taagctcttg aatagttttt
    14161 acaagcataa caatcacatt cagggtcaag tggagtaaag tcttcagcat aagttgcatt
    14221 tctaactact actttacctt ggctagtcat tgcagttcca tttctagcga tacgagtagg
    14281 tagaacacaa tcaaacatgt ctactcctct tataacacct tctactaagt catctggact
    14341 accaactccc attaggtatc ttggtttatc ctttggcata agtggagttg tatgctctaa
    14401 cacgtcatac ataagtggtt ttggttctcc aacactaagt ccaccaatag catatcctgg
    14461 taaatcaata ttagttattt cttttgctga ttgttccctt aagtctttat acatcccacc
    14521 ttgtattata ccaaataaag cttgcttgtc ggtattatta tgggcatctt tacatctttt
    14581 taaccatctt gtagttcttt ctaaagaatt ttttacatat tctctatctg atgggtatgg
    14641 tgcacactca tcaaatgcca tcattatgtc tgaacccaat gcattttgta tttccatagc
    14701 tttttctgga gttagaaaat gttttgaacc atctaagtgt gacctaaatt ctacaccttc
    14761 ttcttttatc tttcttaaag gccctagact aaatacctgg aaccctccac tatctgtaag
    14821 tattggttta tcccaattca taaacttatg aagaccacca gctcttttta taagttcatg
    14881 acctggtctc atatataaat ggtatgtgtt actaagtatt atttgtgaac caatctcttt
    14941 taattcttct ggtgtcatag attttacagt tgcttgagtt ccaactggca tgaatattgg
    15001 tgtttcaata atcccatgtg gagtgtgtaa tcttcctaac cttgcaccac tctgcttaca
    15061 agtctttatc aattcgtatc ttactgcgta cataaagttc tccttaatca tatttatttc
    15121 tcattatttc ttaagatata tttgtaataa gctattcata taatttattg tctaaataga
    15181 tttatcttcg tcttctttgt tctgttgttc cttaattgct tcttcatcat gaatactcat
    15241 tatattaaga gcactcttgt cttttgttac taaaaacttt tttatagcaa atagtcctgc
    15301 tatagctata actcctatta aaacatctat cataccttca tttttaggca gtagcaacat
    15361 ttttctagca attgcgtaaa gtaatgcctc aataaatgct cctggtatat gaagagatag
    15421 cattactaca agttcaacac ctattactaa aagtaatatt tgtgctaaaa aatcattaag
    15481 ctgactgtat tgtactggat tttgaaaatc aactatatat gctccccaca taagtcttag
    15541 aacatctata gttcctaaaa atactgctat tagaactact actgctaaaa cacgttcaaa
    15601 tataaaagca atctttaata tagggttatt ctttttttgt ttttgtaaac tatgcatcca
    15661 ttacctccct actttataat catagcatct ccaaaactga agaatctata tctttctttt
    15721 actgcctcat tatatgcatt taaaacatta tcctttccac aaatagcact tactaacatt
    15781 attagtgtag actctggtaa gtgaaaatta gtaataagtt tatctaaaac tttaaattta
    15841 taacctggat atataaatat ttctgtccat ccactagttt ctttcatctt tccatcctca
    15901 ttacaagctg attctatagt tctacaacta gtagtaccaa cacatattac attttttcca
    15961 ttttcctttg ctctatttat tttgtcagct gcttcttggc taaccatata atattctgaa
    16021 tgcatcttgt gatttaaaac atcctctact tttactggtc taaaagttcc taagccaaca
    16081 tgtagagtta caaaggctat atctacacct ttttctttta ttttatttaa caattcttct
    16141 gtaaaatgta atcctgctgt aggtgctgct gctgaaccat tatgctttga ataaacagtc
    16201 tggtatcttt ctttttcatc tagtctagca gtgatatatg gaggtagtgg catatttcca
    16261 agttcatcca atatttcttc aaaaattcca tcataatgga attttataat tcttgaacct
    16321 tcatctgata aatctacaac ttctccaatt agctttccat ttccaaaaga aaatttagtc
    16381 cctacttttg ctctttttcc tggttttact aaagcctgcc aagtatcttc ctctgttctt
    16441 tttaataata aaaactctat tttacctcca gtttcaagct tctctcctat taatctagct
    16501 ggtataactc tagtattatt taatactaag caatctcctg gatttaaata ttctattata
    16561 tctctaaata ctttatgttc aatattacct gtctctttat ctaataccat caatcttgaa
    16621 ctagctctat cttctatagg aacttgagct ataagttcct gtggtaagtc aaatttaaaa
    16681 tcacttgttt tcaatgttaa acttcctctc ttaaaatttc tccagctaca ataatatcaa
    16741 aaaaacaact tattttccac aatattacca taatctatca agaaattgct atttttaaca
    16801 gacaccatat ccacaatata tagatatttt tccacgatat acatgtctta tccacaatat
    16861 atagatacaa tacacacaat ttttatcgtg tttatccaca gtatctacag atataattac
    16921 cattttgtgg atatgtttga atttttagcc attttagaaa tattttaatt taatgactct
    16981 tttattttat aaatactcgt ataatctatt tttatttttc attaggatat ggaattttta
    17041 agtgttcata tgctaatggc atggctactc ttcctctagg acctctattt ataaatccta
    17101 attgaagcaa atatggctca tatacatctt ctattgtatt tctatcttct ccgatagaag
    17161 ctgccaatgt atctaaaccc actggtcctc ctctaaattt ttctattata gtcataagaa
    17221 gcttctcatc tacaaaatcg agacccaaac tatcgactcc taaaagttcc agagcatctt
    17281 ttgccacctt atcagttatt tttccatcag ctctgacttg tgcaaaatct ctaactcttt
    17341 ttagtaatct atttgctatc cttggagtcc ctcttgaacg ttttgcaagt tctaatgctc
    17401 cattagactg tatctctgca tctaagatgc ttgaagacct aagtactatt tttgaaagtt
    17461 catcaactgt ataataatcc aatttacaaa taacaccaaa tctatctcta agtggatttg
    17521 taagcatacc agctcttgta gtagctccaa taagtgtaaa tttaggaagg tcaagtctta
    17581 tgcttctagc agatggccct ttccctatta ttatatctag gcaaaaatcc tccattgctg
    17641 gatataaaac ttcttcaaca cttctattga ttctatgaat ctcatctata aataaaacat
    17701 cattttcatt taaattcgta agtatggctg ccaaatctcc agctctttct attgcaggtc
    17761 ctgacgtaat tcttaaattt acccccatct cattggctat tatacttgct agtgtagttt
    17821 ttccaagacc tggtggtcca tataaaagca catggtctaa ctgctcattt ctcgatttag
    17881 ctgcttctat aaatatacta agttgttctt tggatttttc ttgacccaaa taatcttcta
    17941 aagtttttgg tcttaaactg ttttctatat ctatatcttc catcttcatt gtagaagtta
    18001 ttatcctatt ttcatcttca aaaccttgca tttatacccc tcctctcata cttttgaaaa
    18061 tctactttat atattttcaa atttacataa actccttaaa tattgtttta aaatccaaat
    18121 attataaaat ccaaatacta tttcaaggat ttactcatta tatatgtaag tgctttcttt
    18181 ataatagctt ctgtattcat accatctttt ttacattttt gaactgcctc ttttgattcc
    18241 gacaaagtat agcctaaagc tacaagtgca tctacagact catcttgtga tatcaaggta
    18301 ggtttttgtg ataataacgt tggttcaaac tctatgttat ttttgtctac cttatcctta
    18361 agctctaaga cgattctttc tgctgtcttt ttaccaacac caggagcttt ggataatttt
    18421 ccaatgtctt cacttaaaat atatgctcct aactgtgctg gtgatgcaaa tgatagtatt
    18481 gaaagcgcca ctttaggtcc tattttagat acagatgtta gtaattcaaa catcttaagt
    18541 tcttccctac ttacaaaacc acaaagactc atatcatctt ctcttacaat taatttagta
    18601 tatatttttg tagcttctcc cacttgtaaa ttcattattg tattggatga tacatttatt
    18661 ttatatccta tcccattatt ttcaacaact atactgtcta tataaatttc ttctactgta
    18721 ccttttatat aactatacat acttaccacc tatattcttt agagtttttt caagtttgtt
    18781 tgaatgagca tggcaaatag ccacagctaa agcatctgca acatcatctg gttttggaac
    18841 tttttttaga cttaaaaatg aagttaccat ctgttgaact tgtgccttat ctgctctccc
    18901 atatccaact acaccttgtt ttacttgaag tggagtgtat tcatatacag gcttcccatt
    18961 atgagcacat gcaagcatag taacacctct agcttgtgca actgttatag ctgtttttac
    19021 attcttgtta aagaataatt cttccattcc aacttcatct atattgtaat tctttactat
    19081 tgtatcaatt cctttataca caagttccaa tcttctcgat atattcatat gggcatgtgt
    19141 tgtaactgct ccataatcga ttactttaaa cttgctattt ttgtattcaa ttataccata
    19201 tccaactatg gctatacctg ggtcaatccc caatattatc attttttaaa attcccccta
    19261 aaaataaaag aaataccaaa atgtatttct cataaaaact tatgttctaa atcattatat
    19321 cataaataat attaacaaat cataaaatgc tctatgtaaa atataaaatc aaataaaaaa
    19381 gttatatcaa agcaagattt tacctcaata taacttttat atttattaca aataaattat
    19441 tgtattttta taggaattaa atgtgactac aattttaata ctaatctatt taatattaaa
    19501 ttatttatta ttaacttact tagtatttaa cttgaaataa tattaattta ctattaactt
    19561 gcaaagtctt ctaatcttga ataggcctct tcttcagtat ccataactac accttttttg
    19621 atttcatctt gaactgtttt aggaagtgaa tctactctta tttttgtttt ttctactaat
    19681 gttttacttc cgctatcatc atatttatat agtgctatat ttccattatc attttcaata
    19741 gtatatttac cttttatagt aacatccatt gcttgtacat ctttattatc actatattta
    19801 gattctacca atatgatttc atttttatcc atactcttta tttttttagt tggatattct
    19861 tttttaaaat atgatactat ttctgacttc gtcttatcta ataatgactc tggaactatt
    19921 cctgccattg taagtgttct cttatagtta gtttcatttt cgccttcact ttgaagccaa
    19981 acttcacaat ttttatttaa tccaaaagct tcttttgact tttcattcat attcgcacta
    20041 gtacttacaa cttcaccagt ttgaactcca ttgtgtttta atcttgtccc tatataaact
    20101 ccgctactta atacaaatac tccaaccagt attaaggcag atattttcca aggaaataat
    20161 tcttttttct tcttttcaaa cattgattac gcctcctttt tctattattt tctccaagct
    20221 gtaagttttt atacaattta ggtaaatttt agaagaaaat atatttatat ttcaaattac
    20281 tctaagaata gatattttct aaaaggtagt tttctcttaa tggttatatt cttgtaatta
    20341 tatggacata atttataata aataatcgtt taggaggtaa taactttgga aagaataaac
    20401 tgtaatgtaa ttaactgttc acataacaac agccatatat gttatgcaga taaaattttt
    20461 ataaatggtg aaaaagctca caatgacaga catacttgtt gtagttcatt tttagatgaa
    20521 tctatttata gtaatttatc tagcaacgtt aataatagaa attgtgagga attagtttgt
    20581 actgtaaaaa attgtaaata caacaaagat ggtagcttat gtacacttga taatatattg
    20641 gttgctcctg aaactgatag agtaaacctt tatattgaaa catgttgctc tagtttcgaa
    20701 tgtaaatagt catagtataa atataagggt gtcaaatgta attaaactaa catagtgtag
    20761 agtatctaca actattagtt tgattatact tgacaccctt atttatttta aataaaattt
    20821 cattattata accatgttta taatgttcta actgtaatta aatttgataa atttctataa
    20881 attggtataa tcaatatgta aattgaattt agtaaattaa tcataaaaat aaaatatcga
    20941 gtatatagtg ttatactaac tagaaatgag gtgcttatga gtacatttta tattcaattt
    21001 ctttattttg taatttatag ctttatagga tggtgttgtg aaactacata ttgttcagtt
    21061 ttacaaaaac aatttgtaaa tagaggtttt ttaaatggtc cattttgccc tatatatgga
    21121 tttggagcat tagcaatagt tgctaccttg actccttttg tacacaatat tcctttgtta
    21181 tttttgttta gtataattat aactagcata atggagtatt gtacgagctt tattttagaa
    21241 aaaatattta atatgacttg gtgggattat tctaaacata aatttaatat tcatggaaga
    21301 gtttgtctgg aaaactcact tatgtttggt gtattgtcat tgattgtaat gcttatagta
    21361 catcctattg tggttgattt tattaactct atctctaaaa atgtactatt tatatttgct
    21421 atatctatag aaatttattt tgttttagat ttagttatca cagtccatac aattttacaa
    21481 ttaaatggta agttaaaaca aatcaatctt ataattaagg aattaaaaga taagaaagaa
    21541 tactacaaac ttattacaca agaaactata gaaaacaaac ttgaatcttt agttgaaaat
    21601 agactggata ctttggaaga taggtttgaa atacttaaag aaaaagaaaa ttatcgctat
    21661 gctaaaaatc gtattgatga gctaaaaaat aaacttaata ctttgctgtc taaccacaaa
    21721 ttacttcata gacgtataat caaagcattc cccaacataa gctctaataa gcatacagat
    21781 attttaaata aaatcaaaga aaatattaaa tcaattaaaa aagataaata ataaaataaa
    21841 cacataagtt aaataataaa aatactaata cataagatta aggtttagaa tattttttgt
    21901 aaaatactct aaaccctaat taatatacta ttatttttaa tcttaattta taattttagt
    21961 ttattttact tttaacacag taaatttaag cgtttaaact tcaatacact aatatactac
    22021 cccatcaata tctcaactga ttctctaagt gtgctaatct ctcccacatt tccagggaaa
    22081 attatatatg gcatattagg aaatttgctt tctttgcctg tcatccatac tggtatacca
    22141 ggttttatct gtcccattac tgtagctttt tttactctta gtgctttagt accaacatca
    22201 ctagaagtaa ttccaccctt agctataata aaatttggtc ttacattaag cataccaatt
    22261 atactggtaa ctgcatctga tatttctaca gaaatcataa gctgtttatc tttatcattc
    22321 gtatccaagt caaaacgctc tcgtctagta taaacagcaa cagttttacc actgcttatt
    22381 ttttcctcta caacttttat aactcttttt acctcatttt ttagaccatt ttcttgaaga
    22441 actaaatgtt gattaaattc tataaattct atcggatatt tacaattttt aagttcttct
    22501 aactgttggg tagtcttatt cacatgtgaa ccaacaagta taattcctcc attagtatta
    22561 ccttttgata ctaactcatc cttagtaagt agttccttgt cactcactcc gccaagtact
    22621 tttgttatgg cagcagcgct tctaaacata aattccttac cactatttac tgctcgtata
    22681 aacgcaattg taaatacctt tacatctaca taatcggttg catttacaat aattttatta
    22741 aatccttcag cttttttaag tttttctgtt atagcttcaa tatttagctc tctaagttct
    22801 tttgacgaaa tatatatcat atcactagat ttgtactttc cttttgtctt ttcttcacac
    22861 cactcaccta tatcagatga tttatatcca aaagatttat cttttgcaaa ttcagtcatt
    22921 cctgctggta caagtatttc tccttcttta acataatgta cattatctat agtaaaccta
    22981 ccaccttctt taaaaaatgg cattattatt tcaccctgaa ataacttccc cgataatctc
    23041 tctacttcgc tttttaataa attagtttca agaggataat gtcctctcat agtagaatca
    23101 ctacgactta tgattataaa atccttatta actttctttg atacatccac aatattcttt
    23161 gaaatttctt tatgtgcttt tgtagtttga gcaacagtaa atccccttga attagtaagt
    23221 ataaaaaaca tactattttt ctcattaaaa ccttgttcca tactatcctt atcccaatca
    23281 gtataaacag aaatatcatg aactgtttgt acacctgttg ggtcatcatc taatacaaca
    23341 atttttctat ctaaatactt aagctcatct gcaagaagtt catttaatct atcctcatct
    23401 acttgtttaa aagtattaag tatatctata ctaattggtt ttacttctct catttaaaac
    23461 acccctttat gtaatttgta tagtctaaat gtaattttat ataatataaa caatagtttg
    23521 ttatttatag acctggaagt ggtataattc catttataac actaagcaat aaaaccatta
    23581 taaatgctac aactccagca atggttcctc caattgtcca agagtttaaa gtatctttaa
    23641 ctgataatcc actaaatctt gaaagtaccc agaatccaga atcatttgga agggagaaac
    23701 caactcctcc agcacatata gcaagcccta ctaaaactgg tgacattcca gttgccaaaa
    23761 ttgtaggtcc taaaattgat gatgttgtta ctaaggctac agtagcagaa ccttgagaaa
    23821 ttctaagcaa ggcacttaat aagaatccaa gcactacaac tgatatacta agaccagaca
    23881 tagtatcaac taagaagtta cctataccac ttgcatttat aacactgcca aacgcaccac
    23941 ctgaccctgt tatcaataat attagccctg ctgaatcagc agcttcaata actacatctc
    24001 ccataggttt atttatgtat ttctttaaaa atcctattgc caccaatatt ccaagaagta
    24061 ttgctatgtt tttatctcct ataaatgcaa gtactccact cattgtagaa cctttttcta
    24121 agaacatact aaatacattt gatataagta taagaagtat tgggaacaat aaagaaaaca
    24181 tagaaattcc aaaacctggt actttagaag aatcatcatc ttcaattttt atgctatctt
    24241 ttccctgctc taaatttttt tctctatcat tctcatcaat agcataagct ggatattttt
    24301 caaaacgttt tccataaatc catccaccta taagagctgc tggaaaagca acaattatag
    24361 aataaagtat aaaactacct acatttgcat ttacatttgc tgcaactgcc aaaggtcctg
    24421 gtgtaggtat tacaagtgca tgacctacta tagtcccaac tcctaaggca catacaaaaa
    24481 ccattagaga tttcttagtt actctcgaaa catacttaat tataggcatc attataacaa
    24541 aagctgcatc cataaaaact ggaattgaaa ttaaaaaacc tgctgtagtt actgctaaag
    24601 cactgttttt ttctccagtc ttagctaaca acccctttgc aatagattct gttgctcttg
    24661 attctgaaag aatatttcca aatattattc caagtccaat tacaatacct atactaccta
    24721 atgtatttcc aaatccagtc gatattgtgg ttgatatttc atttataggc attctaacca
    24781 taaagcctgt aattatagat gttatcagta atgccaaaaa cggatttact ttaaatttaa
    24841 taatcgatac aagtaaaatt cctatagata taacaaatgc tatcaaaagt ccatatcctg
    24901 taatcataat ctttacccct ttatcattct actttattat ttatcaattt tatttttctt
    24961 ttactatgat aacttaacct cgctgtattt atataatcta atcctaataa tatgtattta
    25021 attatattga tatatttaaa tattaattat tgtgtttttt tatttcaaca cctgccaact
    25081 tttcaaaata ctgtgctatt ccactatggt catcttccaa atgtccatgt acttttaatg
    25141 tctgcataat ttctaataat tgacttgtca taggtagcgg tacatctaaa ttgtgtgctg
    25201 tttgcattac attcttaata tctttcaaat taatagatat ttttccacct ggtttaaaat
    25261 cacgattcat aatcattggt atcttcgcat ccaatattgt actaccagct aggcctcctc
    25321 ttattgcctt atatactttt tctgggtctg cacctgcttt tgctgcaagt acaaatgcct
    25381 cagaaactgc tgctatcgtc aaattaacaa ttacttggtt tgtaagtttt gtaacacttc
    25441 cactaccatt atctccaatt aaaatagatg agcttcccat tatattaaaa aatggctcta
    25501 ctttcttata aatttcttcc ttaccaccag ccataaaagc aagtgtacca tcaatagctt
    25561 ttggctcccc tccacttact ggtgagtcta taaattctaa tcccatatct tttaatttat
    25621 ttgcacacaa tatggattct gtaggagtaa ctgaactcat atcgactact atacttcctt
    25681 cttttaaagt ttttgccaat ccatccatcc caaacaatat atcctgcaca atagttccat
    25741 ttggaaggat tgtaaataca atatcacatt cttgacccat ttctaaaaca cttgcgtatt
    25801 ttgctccaca tgatataagt tcatccacag cagatttatt aatgtcatac accaaaagat
    25861 tacatccatc ttttaataaa ttttttgcca ttggctttcc cattattcct aatccaataa
    25921 atcccaattt cattttataa ccctccatat cttcacattt ttgaaaacgt tttttatgtt
    25981 ttagagtata ctacatacca gtataccggt caatataaaa tataaaagta tttattttaa
    26041 caataaatag taatttttaa agtcatttat tatatttagt catcctatat aagttttaat
    26101 acatactatt gttttcaaat ataatatact acttttacag ttttgtattt taactaattt
    26161 caattagttt taattaatct gcctttaatg ttaatcatgc ttcacacttc aataattttt
    26221 tatatttttt aatcttatct gcaatttaaa ttgcaaaaga ttgaccttat tttcactatg
    26281 ttgtatgctt aaaattatat aagtttttgt atttttatat tgtttagggg ggtattatta
    26341 agtatggcta catttaaaag attacaagaa caagcatatg actacttaaa agaattgata
    26401 ctatctggag aaatgataga aaatgaaata tattctgaaa caaaacttgc tagtgaaata
    26461 ggtatctcta gaacacctat aagagatgct cttcaaagac ttagtcaaga tggatttata
    26521 gatataatcc caagcaaagg atttagaatc catcaaatta cagcaaatga aattgtagag
    26581 atattccaaa tacgctctgc aatagaaggg ttttgtactt ttttaattac aagtcaatac
    26641 aaagaagcta gagcagtaga aactataagt aaattaaaac atcttttaga taaacaaaaa
    26701 gatattttat taggtgataa aaatttaaac tcatttgcag aatacgatac attatttcac
    26761 acaactatag tttcatatgc tcaaaatact gaatttgaca aaatgtttaa caattacatg
    26821 tacagaataa aaaaattagc tctcgattca ttgtcacatg aaggaaggct tgaaacaaca
    26881 ttaaaagagc acacagatat ttttaataat attgcaaatg gatgtattga agatatttac
    26941 agaactactc tcattcatat ggaaactcct aaatacatta atttagaaga tttttgtaac
    27001 aataagttat tttagcatta taccttcatt tattaaaaat atatctatct caaattaatt
    27061 tcctaattta taaaaaatat tctataatta tattgtaact aatacttatt ctaaggagtg
    27121 atttttttga acgaagatgt tgtaactaat gaaactatcg acaaagatta tgctattgaa
    27181 gaagttcgta tggcatgcaa acattttggt gatttatatt tttatttttc caaagtgtta
    27241 tttgaagagt ttggtgaaga taaaactagc gaaatattaa gaaaagtttt atttgaaagg
    27301 tctgaagaaa gagctattgc tatgagagag agagctcatg aaaatggaga tgaattaatt
    27361 gcagacaata ttattagcac aactgatgtt ccatttctag gatgggttcc tgaatttgaa
    27421 gagttacatt gcccctatgg agcttcttgg cttttaagat ttgaggaaaa tccttggttt
    27481 aaaaaattcg cttctcttta ctgtgatgtt acagatacta ctgtagctga agtatttaca
    27541 ggggatacgt cccataaaat aacaaaaaac attctatggg gagataaaag ttgtgaaaga
    27601 atatatttcc atgatgacaa ggtatctgaa ggtaaatata cttatggaaa taaaaactgt
    27661 aaataaataa tttaaatttt ctatattcat atactatatt ttgtactttt tcatataaat
    27721 attataacta gtcttttatt ttacttttgt ttaacctaaa gataatttac ttttaatcta
    27781 tatgaattat catataaata atcagaaagt tatctttata aattatagtt ttagatttat
    27841 aatttataaa atatttatgt tctttgtaaa attttttaga agcttctaat gttatgctat
    27901 aaaactatct tgagaagggc tgattgaatg tttaataaaa tatatgaaaa gaaagaattt
    27961 atagtttttc aagttaaaaa aggttatgta gtttataata ctagaaagag ttttgaagaa
    28021 ggtcatacac atttaaagca ttttgaagca gcaaagacag ctattgattt agcaataaat
    28081 aaaaagattc ctagaagcaa agatggatat tatctgacta gtttaattcg cataagtgat
    28141 gatggttatt acattgataa gttaagcgaa ttgttatatg ttagagaaca aaaaggtaaa
    28201 aaagaaaagt actgtaattc tggttatcag atgtaacaag actagttgtg aattataagt
    28261 accaatcata aataccttta gtcttaaaat caaagagtat cagtaaatct ataaaaaaac
    28321 aacttactga tactcttttt aattatatga ttaatatttg aatttgatac aaaattttat
    28381 acaaaagttt atgttatcta ttctgattct ttgtctgcaa attggctatt ataaagcttc
    28441 tcataaaatc cacccttttc cattaattca tcatgattcc cctgctctat aatacttcca
    28501 ttgttcataa ctaaaatcaa gtcagcattg cgaattgtag aaagtctatg tgctataaca
    28561 aaactagttc taccattcat aagatttctc attgcttttt gaagcataag ttccagccta
    28621 gtatcaacag aactcgtagc ttcatcaagt atcaatattg aagggtctga tataaaagct
    28681 ctagctatgg ttaaaagctg tttttcccct agagatatat tagatgcttc ttcatttaaa
    28741 aacatattgt atccatctgg aagagtggtt ataaagtgat gaacatttgc tacttttgct
    28801 gcttgtataa tttcttcttt agtagcccca aatctaccat attctatatt ttcaaaaatg
    28861 gttccattaa ataaccatgt atcttgaagc accataccaa acattgaacg caaatcttta
    28921 cgtttcatat ctcttatatc tactccatca attttaatag cacctttctt tacatcataa
    28981 aacctcatca ataagtttat taatgttgtt ttacctgctc cagtaggtcc aacaatagct
    29041 accatctgac cactttttac ttctgcattt aaatcttcta ttaaagttga attttctcca
    29101 tatccaaaat taacatgctc aaatgtaaca tttcctttta cattttctat cttaactgga
    29161 ttttcaacat caggtatttc ctcttcttcg tctaaaattt caaatacacg ttctatagct
    29221 gcaaaagaag attgtattac tgtagataac tgagtcattt gtgaaagtgg ctgatttatc
    29281 tgccatatat aacgcacaaa tgcttgtaaa tttcctactg ttattcctcc acttactgca
    29341 tatatagaac cgacaactgc cacagctgca attccaaagt aagttactaa tgaaaccata
    29401 ggattcatca tacttgatat aaattgtgcc ttaaatccat tttcacaaag ttcttgattt
    29461 acttttttaa attcttttat agaatcttct tctttaccat atagttttat ttcattaaat
    29521 ccagtataca tttcttgtac ttttccattt aattttccaa gagcattttg ttgcaatgaa
    29581 aatctacttt gagatttttt tactacaaat ttagatacaa aataactaat tggaattata
    29641 aaaagagcta taagagccat atatatatta attgtaaaca tcattgaaag tgccaaaatt
    29701 atgactaaga ttgagtttac aatttgcata aaactctgtt gcaatgcatt tgatattgta
    29761 tctacatcat ttgatatacg acttaataca tctccaaaac tattactatc aaaataacta
    29821 ataggcaatc ttcttatttt attttcgact tcatttctta aatctctcat tgtgttttga
    29881 atagcattcg taagtagaaa acttgaagta tacgtaaaaa ttgcattggc aaaatatata
    29941 catgctaaaa tcaccaatat ttttgttaca taatcaaaat ttacggaagc ccctggtact
    30001 ccttttgcga tactaattac atctttagtc aattgtgtta ttatcaatcc ttcagtttta
    30061 ggtgcaagtg cattcatagt agctgctgaa attatacata taatagctat aataaaggaa
    30121 aatttatatt tctttacaaa tggaagaagt ctaccaattg ttttcttaaa acctttagac
    30181 tttttcatta ttctaattcc tcctttttta actgagatgt tgcaatttca tagtatattt
    30241 cacagttttt taataattct ttatgagttc ccattcctac aacttgtcct tcattgagta
    30301 ctataatctt atcagcatca ataatagaac taattctctg ggcaacaatc aatacaattg
    30361 catcttttgt ttccttcttc aatttagcac gaagtattgc atcagtttta aagtcaagtg
    30421 cagaaaaact atcatcaaaa atgtatattt caggtcttct tataatagcc cttgcaatag
    30481 aaagtctttg tttttgacct cctgatacat ttgctccacc ttcactaatc aattcatcaa
    30541 actttctagg tttttttgat ataaactcat atgcttgtgc aacttttgcg gaatattcta
    30601 attctgactc tcctgcctta tgtttcccaa atctaatatt atttgctatg ctaccagtaa
    30661 aaagcagtga tttttgaggt atgaatccta tcttttttct taaagctttt aaatcatatt
    30721 ctcttatatc tactccattt atcttaatac taccttctgt tacatcataa aatctaggta
    30781 tcaagttaat tagagtactt ttcccactac cagtacttcc tataaaagca actgtttcac
    30841 ctgtttttgc agtaaatgaa atatccttaa gtacagaagc ttctccatct ggataggtaa
    30901 aagttacatt atcaaattct atgataccct tattttcagt atccttaatt ccattttcag
    30961 gattttttat caatggttct tcatttaaaa gttcttttat tctatttgca gatacctctg
    31021 ctcttggata cataataaat accattgaaa aaagcataat tgaaaacatg gcatggaaaa
    31081 gatattccaa aaatgcaacc aactgtccaa cttgaagctc tccaatattt atcttctcac
    31141 ttgaaatcca aaatacagcc aaaacagcta tatttaatag taaaaagaat gctggttgag
    31201 taattgacat aagcttaaat agtttcttag aaacattagc ataatatgta tttgtttttt
    31261 caaatcgctc tgtttcataa tcatcatttc caaaagctct aattactctt attccagtta
    31321 aattttctct cgatataagg tttaatttat ctagtccttt ttgttgtttt gaagatattg
    31381 cctgagatac ttttgctatt attgctactc caataattat aaaaggtact gatatagcca
    31441 atactataga aagttccaca cttgttctaa ttgtcattat tatacttata atgaacataa
    31501 ctggagttaa taaggcagtc cttagtagta tattaacaaa ttgttgaatt tgaaatgcat
    31561 cattcgttgt tcttgtaatc attgaagaaa ttccaaattt attgtattca gtatgtgaaa
    31621 attcttgtga tttctcaaat atgtcatttc ttatatctct ggttacactt gttgatacct
    31681 tagcagaaca ataacccaac aatatactac ctacaacccc tataatagaa ataataacaa
    31741 tcactattcc catttgtttt atgtaagcta tattctgatt tgcaatacca ttgtcaatta
    31801 ttttagctat tatagttgga atccccaact cgactaatgc aaaactaaat atagccagta
    31861 tgtttaatac tattaataac ttataattct ttaaataact taaaattaat ttcatatttt
    31921 tctcctttct taatttttga gatagtgtaa tcatgtaata atactaaatt tataaatgct
    31981 taattttata aaaaaaggag aaaagagtta acgcactctc ttctccagca tattcttttt
    32041 aatacaccct ccgacaagtc gcttatatgt taacatattt gacaagtaat gtcaattcat
    32101 atagccaaaa gtcttttaaa tgcttcattt cataacattg taacaaattg gcatgtaatt
    32161 tatttttgtt ttttactgta ttccaatttt acaagttctc caatattact agctttctta
    32221 aaattcaaat tagtcttatc tataccagac ttaaatagtg aaatccctct ccccaatatt
    32281 attggcaata tatatatata ataatcatca attaagttat ctttcataaa taattttact
    32341 atatcgcctc caccaactat ccaaatatct tttttatcct tctcttttcc aatttgctca
    32401 attaattttt taggttctaa attaatttat aatgtgatta ttctatgtaa acatcacttt
    32461 ttactcattc aataataccc tattaataaa tcctcaaact aatttaaata aactttgcat
    32521 aaaattaaaa atatattata taaataattt aaaactacac taacttattg aaaattctaa
    32581 ttattacaaa taaatattgc tctctgttag cgctagttct ataatataat tataagctat
    32641 taatattata aagccgatat tactaatata ataattataa tacttatagt taatttactt
    32701 ttgttgaaag gtggtaaata acatgaaaat ttcagaagtc gctactccaa attttttgct
    32761 agatttagac cagttagaaa agaatataga taaaattcaa caaatttgta caaataataa
    32821 taaacaactt tggcctatgc ttaagacaca taaaagtact tacatagcga gacttcaaaa
    32881 aaatgcaggt gctagtggtt ttctagttgg aacacttgat gaaggtgaag ctctgataaa
    32941 agcaggtttt gaagatatta tgttggctta tccttacatg ggagaagtaa atataaatag
    33001 aatcgtaact atggcatcaa aaataaattt aatctgtgct acagataata tagaatgtgc
    33061 taaggcttat agtgaagctt tttctaaatc aaaaatagag tgcaagctac ttattattgt
    33121 agattgtggc ttacaccgtt ttggggttga accagagaaa gtggttgaac ttgctactga
    33181 aatttctaag ctagaaaaca taaagattgt tggtataagt tcgcatccag gtcaagtgta
    33241 tggttgtagt tctccagaag gtgttccaga tgtttgtgtt caagaagatt cttctatgga
    33301 gaaagcatac aaagctctaa ctgataatgg atttaatata gaaattgtcg cttctggtag
    33361 tactccaaca gttgaatctg aagctgcttc taaaactata actgctgtaa gacctggaaa
    33421 ctatgtatac tatgatgcta tacagatagg tttaggttgt gctactgaag atatgtgtgc
    33481 tcttactgtt gtgtgcactg taatctcaaa aaatagcagt ggatactatt taattgattg
    33541 tggaagtaag tgccttggac ttgataaagg tgcacatgga aatagtagta ttgttggtta
    33601 tggtagggta tgtggacatc cagaacttac tattgattca ctttcagaag aagttggaaa
    33661 aattaaagta aatggtgaaa ctgatataaa aattggtgat agaataagaa ttatacctaa
    33721 tcattcttgt tccactgcaa acttgacaag taatttatta ggttttagag gagatacaat
    33781 agaaaaagtt atagaagtag atattcgtga aaattcaaaa caaatcatcc tttaaaaaca
    33841 gatttattct gatattaaca tgaaagtata tttttcttaa aattatttct aataactaat
    33901 gttaatgttg gataaataaa aaacataaat tctagaaata taaatttaaa agaagaggct
    33961 gtctcaaaat agagataagc ctctctttca ttgttgaaat tatgaaaata tacttgattt
    34021 catacaaaaa gagtatctca tgaactaaaa agttcacttt gagatactct ctttttttta
    34081 attaatatac acattaatta ctatcttagt ttattactat atatcaatta ctattcatta
    34141 atccttgtat atattaattc ttatatatca tttatagtta ggttataatt ttatgttatt
    34201 tacattaatc ccataacagt gagtaaaact cttactatta acatccccac tattgcatca
    34261 aatataggaa ctgccaacag taacattcta tacttagtac tggcatttgc tacaagcact
    34321 attctggcat aatgaccaac tagagtaccc attaacatac atggcataat taatatggtt
    34381 gcttgtggtg cagtgattag accttgtgca aataagtttg cagctgtagc tgctcctgct
    34441 gccttagcaa agaatgctgc tatcaaaact acaacagatt ccccaggtag tccaaaaata
    34501 cccattactg gtccaaaaat atttcctaaa atatcaacta aaccagttaa ttgtaaaaac
    34561 tgcactatta cataacccat tatcatggct ggtaatatct gttcaacacc tatgtaaaaa
    34621 cctttttttg ctccccccat aaatatctca acagcagttt tcttaggttt actatttaca
    34681 attgcatttc cagtattttg ttgactcata ctacacagcc tccttagcct tattcttttt
    34741 atttcttaca cctatgatta atctaactag attagcacca agtattttac agaatatctc
    34801 tataaggatt attggaccta atgccaataa tgctattggt aaaagtggag cttgagtatt
    34861 tattgtgttc agtataacag ctgaaccagc atattgatat gctacaaata tagttctttc
    34921 atcatctgtt atttccccac tttcaaataa ttctttcgtc attattgagg ctacatctga
    34981 actagtaaat gaagatacaa atgctattcc tgctattcca ggtataccaa gcagaggtct
    35041 aagcaatgga ttaaatatct ttgatgccgc tttcattcct cccatagatt caactacatc
    35101 tataagacct acagcaaaac agacagtcgg aatcaaagtc agagcaaata agaaaccatc
    35161 ttttgctccc gttcctcctt tacccataaa gtctacacca tctgcaatag taccaaatga
    35221 acctgtcaaa ttagcaaaat ctaatgcttt aaggaagcct tgactatctt taaacactcc
    35281 tgaaaataat actatcaata caaataaaga taaataccct ttccatgtta ccttattatc
    35341 tccagctgtt acatccatat aaaatccccc tttatacctc aaatttatct aagtttaaaa
    35401 taactgtaga aattaatttc accctctcaa acatagaatc tactactgca tattctcttg
    35461 atgtgtggtt ccattctcct cttacaccaa atgaacagat tgtaggaacg tttgcaatag
    35521 ttaaataact tgcatctgaa ctacctccaa gtctcttagc atttaattct ccaaatccat
    35581 tttcttttga cacttcattt acaaatgtat gaaatctcat aacatcttct gtagtttcaa
    35641 atggcatcat ttcacttata aaattaactt ctgtagaagt tccttctatg taagtttctt
    35701 tacatatctc tctaacttgt tctttaacat tctccatttc ttctactttt tcaaatctaa
    35761 ggtctacttt tatactacaa tcttctggaa tagaattttc cactcttcca cccttaatca
    35821 cacttacact tactgtagtt ccaacatcta aattagtcaa tttttgtatg cgtagtatct
    35881 tattagccat ttcttctata gcatttcttc caccttcaaa atcattacct gcgtgtgttt
    35941 ctacaccttt tacatgtata ttacatccta ttcttccttt tctacctaca cacaaactat
    36001 tatctactaa tccagtttcc atattaaaag cacaaagacc accttttgct tccctcaata
    36061 taacatctgc acctgttgaa tccttatgtc ctatctcttc atctccagaa aatactattt
    36121 ttattggtct ttctttgtat cctattttat ttaatgcttt aataacatat aaggaaatta
    36181 ttataccacc cttcatatct aaaacacctg ggccatatgc ttttccttct attattttaa
    36241 atggattctc tccaaatgta cctgtttcaa agacagtatc catgtgacct gaaaaaatta
    36301 ttggcttttt atctatatta gaaccaagtg tacctatcaa tgtactacca ttatctccaa
    36361 catctactaa ctcgcaatct aaaccttctt tttcaaactc aaactttaat ctcttagcca
    36421 atttatttac gctttcttta caatgtgtat agctttctat attaacaatc tctttccata
    36481 atgaaactat ttcttctcta ttctcatcaa caaacttaga aatttcattt aaatatgtat
    36541 tcataatctt ctcctttatt ttcaaataaa atgtatttct ttcctaaaac ctaagtttat
    36601 tttaggaaat cttaaaagac tagtccttaa ttacaaaata gcacaattat tcttgccagt
    36661 caacatattt ttcaatcttt tttatatttt ctgatttttc tttcaattat ccttttgtaa
    36721 aataaattga cgcgttttat ctactattat aaaatgaggt tataaattga ttgattagtt
    36781 acaatactct cgaaatttta aaggaggttt tatgaaatat aaaattggtt ttttgacaac
    36841 atcttatttt atgtcagata agtttaaaca agctcttaaa gaattaaatg atacttgtga
    36901 aattacattt attgagctca aaggggagaa tccttttaat aatttaccta atatatacta
    36961 tgagcaagta gataattttg atggatttgt atgtagtggt atagttccat atagtgaact
    37021 tataataaat ataaaagaca taaaagttcc attaaatttt ttaaagcttg atgaaagaga
    37081 tttttataaa tacttattca aattattaaa tagccaaaaa gatattgact ttacaaagtc
    37141 atttatggat tttttaagag aggacaacaa ttattatgat atatattcat taatagactc
    37201 taataaatgt ccatatacaa ttaaagattt taatatccct caacctgtat atgactttaa
    37261 aaaattaaat gataaattat tggaaataca tttagactta ttgcgagata ataagattaa
    37321 cctttctttt actagaaatt acatcattag ttgtgaactt aataagcttg gatatgattg
    37381 tatttacatg gttccatcta cagaatcaat cctgaataca tttaaatctt tggtgaatga
    37441 actaacatta caaaacttag acaaaaataa atctgcaact tgtatagtta cagtaaatag
    37501 ttcagagtac ataaatgaag atttgatatt taaaaatgat gagatacaaa atcaaatata
    37561 taacactata ttaaattctc tatcaagaca tggattctat ggagttcagg tcaaaaaaaa
    37621 tgatatgaaa atagagatac acactactaa agaaatgtta aacaatatga ccaataacta
    37681 tacagatttt tttatttcag aagatttaaa agaaattaaa tatagcttaa atataggttg
    37741 gggcattgga aatacaaata ttcatgcaga gcaaaatgct cgtcaagcta atggtaaatc
    37801 tgcttctttg aatggaaact gtacctttat agtaaatgat actaatgata caataggtcc
    37861 tttatattca aataaaaatt ctaataatat tgaagatagc tcaatagcca ataaagttgc
    37921 ttcttttata cctctatcta atacaaatgt atctaaaatc atgtgtatga ttaatgatag
    37981 aaattcaaat aatgtgtcag cagaaatatt agcagactat atgaacataa ctcttagaag
    38041 tgctaataga atattgagta ttttatataa agcaggaatt gcaactattg taaatacaaa
    38101 actcgataat caaagaggaa ggccaaaaaa aatatataaa gttgatttct tatcttttct
    38161 aaataagatg cagaaattaa attcttaata tttaattttt taataaaagc aatgtatttt
    38221 ctctaatttt aaagaatcaa aatgtttaaa ttttattaga atatacaact ttttacttta
    38281 aaatacctaa accttttatc agtgaaataa accataatat atcgtaactt attagaaaaa
    38341 caaaataatt tcatatacaa ataataaaat agccactaca atccataatt tgcagtggct
    38401 actttttaca ctatcactta ttacttaatt tttaaaaatt aattgtattt tttaaataat
    38461 ttatacatac ctattatcag taaagcaata aatacaagta tatctataaa aataattatt
    38521 gtaacatgtc tggcaatatt gtaaataaaa agtatagaga agatttctat agacaacgct
    38581 acaaaacaca taaaattcgt taaataatct gcaatagtat cactataaaa agcatgtatt
    38641 tgtaaccatc tccatataaa tggacgtaaa agtattctga atacaacaca aatgacaggg
    38701 taggcataaa taaatttttt atctacataa ttagctacac cattattcca ttggatagga
    38761 atttgaggtg gcaactttgg aaatactgtt attgcaattt aaacactacc tctctattct
    38821 attaatttat aactataata tagtcttaaa tattttcact ctataaaatt gtatatttag
    38881 tatatcttaa aatcaaacta attatctttt ataagttttc atacaataat atctcctttc
    38941 aataatatat ctttttttat atttaaaact atcttatttt ctataaaata atgtataaac
    39001 aaggtttaca gtcaagtatt tttattattt ttttgatttc ataaaaaaag catagcaaat
    39061 tatttgctat acttttttac taaattattt attctatatc ttatatgaac ttattgttta
    39121 actactacac aatactagct ttaatcatca tattttttgc aaacatactg gcttcatata
    39181 tttcttgttc atctggatga ctttgagatt cctcatggtt atttaattgt tggcgaatat
    39241 gttcgttgtc aggagaaagt tttagcatct ctttatattt tgctttcaat ccttctgcta
    39301 tcttaccttg acatatgaat gaacctaata tttcattatc ttttgggata attgattcta
    39361 tcttttctat tatactagct ccataacttc cttttttact tgctcccatt gttccaaata
    39421 gtgctatctt tttattgtga atattttcaa gcacttgttt tgaattttta tcacaaattc
    39481 ccttgtccac ccaatagcct aagaatacta tatcataatt ttcatagtca atactataat
    39541 caactaattc atttacatct ttaatgtctt tttcttcttg aatttcatca tatatagtat
    39601 aagcaatctt tttagtattt ccagttaaac ttgaatataa aactaaactt ttcatgatgt
    39661 ctcctcctct ttatctaaat acttatctaa atcaccaaaa atatattaac cttaacaaat
    39721 tatttatttt tataaggata ttctaatcta gtatacatcc aaactgagag cgtgtttgta
    39781 aagcatctgc acacttctta ttacaataac agcacttttt aatctcatct actcttccat
    39841 cttttacttt ctgtaaccaa ttactatctg ctagtaattg tcttgacata gaaaccatat
    39901 ctactctatt atttgaaata atactttcta taaaatctgg gctagacaat tttccaaccc
    39961 cacatactgg aagatttgtg tgtttcttta cctcatcagc taaatataaa aaacagcctt
    40021 catctttaaa gtaaggatga ttattggttg gtatagtatc ttctaatttt gaatgatttg
    40081 caagtgttac atgaaaactg tttacaccta gggattcaaa ttttttaaca aaatactcaa
    40141 cttccgaaag taaaactcct gcatttccat aatgaggatt ttcttgtctt attgcaaatt
    40201 tatagtctat tggaatatcc ttaacttcat ctcggatact actaattatt tcgcttgtaa
    40261 atctacttct attatcacac gttccaccat attcatcatt tctattatta aatatacttg
    40321 atgaaaaact tcctacaagc ctatcaccat gaatttgaat catgtcaaaa cctgcttttt
    40381 ttgcattcaa tgctgttact ttaaataaat ttataatatt tttaatttct tctttggtca
    40441 tatttgttat gtaatctttt actccgtcat tcattatttt ttttatctca tcatgtgaag
    40501 taattcccat cttcatagta tctttaatta aattaacatc ataatctgaa caaaatagtt
    40561 gtgctgatac ctttgcacca gaattgtgta tttcatctac aattttcttg tatttcatga
    40621 ctccatcttc atccgatagg cttatagcta ccttatgaaa actaggtcta atagatacat
    40681 ctcctagagt aatcagagct actcctgact tagcaatatc agaaaacttt ttaatttttt
    40741 cttccaattt aagacccatg cttgtaggtg caaaagatac tctatttttt aattccaaat
    40801 ttccaatttt aattggtttt aataaattac aatacatcct attcttcctc cacagctgtt
    40861 tttatatcct ttaccacatg taaattcttt accagttctt tatattctgt atccgagaac
    40921 tcttttttta tgtgattatc ccactttgaa aatatgtttt ttatatcccc taatacttcc
    40981 tcacccttat ctgttactct caactgaaaa gctctactat cattagggtt ttggattttt
    41041 tctatgtatc catcttgttc taacctagat atagttcttg ttgtatgagc tttatcaact
    41101 tcaaattctg tagaaacatc attcaaagaa caattcctat ttttattaat ataaattaaa
    41161 tagaaatata gaccattcgt aagtttatat ggttttaaac atttttcaca ataaagttta
    41221 aagttttttt gcaagttaca aataatatat gacaaacttt catactgtaa atttttaaaa
    41281 tccatcttaa atttcccttc tataattata atatgtttga ctatatcaac tatattatat
    41341 taaacaatta atatagtcaa gaatatttta ttctctaaat ctatgtttta ttaattcttt
    41401 aaaaaactat tatataaaat aatcatgata aaattagaaa ttggaatttt taatatgcac
    41461 tgtacataaa tatattttat ataaaagttt atattttcaa acaagtaatt tttcgaaaat
    41521 tgtctaaatt cagtaaaaat atggtaatat atacataagc aatataaatc tataaaaagg
    41581 agtgttacat atgatatcta ataaaatgca aactttagtt gcaaatagtt ctgttataag
    41641 agctatgttt gaagaaggaa agaaactttc tgatatttat ggtgaggaaa atgtttttga
    41701 ttttagtata ggaaatccaa gtgttgaacc tccagagact attaaagcag ttataaatga
    41761 tattttaaat gaagaatctc caaatttagt tcatggatat atgaacaact caggatatga
    41821 ggatgtaaga gatgctattg ctgaacacat aaataaaaaa gatggattaa atcttacaag
    41881 agaaaattta attatgactt gtggtgctgc tggtggtcta aatattattt taaaaactct
    41941 tttaaatcct ggtgatgaag ttattgcttt tgcaccgtat tttggtgagt ataaaaatta
    42001 tacagaaaac tatgatggaa aattaataga agttcctaca aatatagaaa cttttgagcc
    42061 agatttagat gctctaaaaa atgctattac tccaaaaaca agagctttaa taataaacac
    42121 tccaaataat cctactggtg tcatatattc tgaagaatta ttaaaaaatc ttggagaatt
    42181 attggattca aaacaaaaag aatttaatac aagcatatac ctaatttctg atgagccata
    42241 tagagaaata atttatgatg gtgccaaagt tccttgtgta ctaaaatact atagaaattc
    42301 atttatagga tactcttata gtaaatcatt atctctacct ggtgaacgta taggatatat
    42361 tgttgctaat gggcaaatgg atgattttga tgatgttatg tcttcattaa atgttgcaaa
    42421 tagaatactt ggatttgtaa atgctccttc tctttttcaa agggttattg caagaagttt
    42481 agatgcagaa gttgatgtaa atatttataa aaagaatttt gaccttctat ataatagttt
    42541 aatcgatatg ggatattctt gtgttaaacc taatggtaca ttctatttgt tcccaaaagc
    42601 tccaattgaa gatgataaaa aattctgcaa tgatgcaaaa caatttaatt tattattagt
    42661 accaggttct tcttttggtt gtccaggtca ttttagagta tcatattgtg tatcttatga
    42721 taaagttaaa agttctttac cagcatttga aaaattagcc aaattatata atttaaaata
    42781 actaaatcaa agtaattcaa ataattaact accttagtat agaatactta cattctatat
    42841 taaggtagtt tataatttta tgtactatat tttatacata ccatattatt ccaatatgct
    42901 tgaatattct tatctatagt actaatataa attacaagga ggtgtttgac ttgaaaaaag
    42961 gttatgttta tataatactg actaccttat tttttagttc aatggaaatt agtctaaaaa
    43021 ctgtcactaa tgactttaat cccttacaaa taactttatc aagatttttt gttggcggtt
    43081 tagtcttact accttttgct gtaaaaagat taagagctct tagtctttct attacaaaat
    43141 cagacttaaa atactttgca tttttaggtt ttatgtgtgt agtagtaagt atgtcattgt
    43201 atcaacttgc tgttctaaac acaaaggcat ctgtagttgc tgttttgttc agttgtaatc
    43261 cagtctttgt aatgctttta gcttacttaa ttttgaagga aaaaatatat aggcacaatg
    43321 taatttcact tatattagaa gttcttggaa ttatagttat aataaatcca ttgcatacaa
    43381 aactaactct tagtggaata ttcttaacat tatcttctgc tattattttt tcaatgtata
    43441 ctgtatttgg taaaagaaaa accttaaaat ttggtggaat agttgtaacc tgctttagct
    43501 ttatatttgg tagtttggaa atgttgatat tggttttact cactaaaatt aattttatcg
    43561 cagatatatt aaataaaaat aagcttcatg tatttgcaaa tatccctatt tttagtggat
    43621 ataccttaca caatatgccc attatgattt atgtattcgt atttgttaca ggtgttggtt
    43681 atgcgcttta ctttatggca atggaagcta catctactag tcttacatct ttagtattct
    43741 tctttaaacc agtaatatct ccaatactag cattattaat acttaaagaa attatcccta
    43801 taaacatggt tataggaatt ttattgatag taattggttc aataatttct attataccta
    43861 cgataattac tcaaatgcat aataaacacg ttgaagcctt gtataaggag tagtaattga
    43921 taatctatca tagttataca taagacaaaa tttattagat ttaaacgcaa tataaaagag
    43981 atgctattat aatagcatct ctttatttat atttatttta aatttattaa aactctattt
    44041 agctaaattt tgcaaaaagc tataagtttg tggacaagct gattttaact tactatttgt
    44101 atcttgattt aaatagtaat atgcaaatga ttctgcaaaa aattcttctg gatatacacc
    44161 taagtagttt acattaccta aagaacgacc ttctttagca aatatttgtt tgaattgtgc
    44221 tgatttagat atatcattta atactatatg gtctattgca tgtgctgttt catgtaattc
    44281 taaatttatt gcatcatgcc ctttaccttt gttactaaat cctattctaa gagctactgt
    44341 acttccacct aaacccggaa catcatccca agtttttcca gtaccttccc atcccttagg
    44401 aactacacct tttaaataag catattcttt ttcatctgtt aactttccac ttaataattt
    44461 tatttttaag ttattttgct ttaatgcatt taaatacttt ccatctatat tagctaatct
    44521 atttaccata gcattagctt cgtttttatc gtaatttcca gttggaaaaa ctactatttg
    44581 actaagtgtg tctttatttt gttgtatagt agtactatct gcatgtgcac ttactggaac
    44641 tgaacttatt aagaatattg atattatagc tattaataat tttttacttg gtctcatatt
    44701 attccctcct ttgagttagg ccgggagtaa taaatttcaa aataaaaaag atacccaaga
    44761 gtatctttgt atatacaaaa agaaattttt actcttttcg gcaactggct ggcatggttt
    44821 actaaacttt agcccctata gctttgcgtg actaggtttc cctagttttg cctcatttaa
    44881 ttttatatct atattatagc ttatatcttt ttaattgtct atatcccttt ggaacttttt
    44941 tctaaaaagt tattattttt ttacataaat cttcaaaaaa aaatatcttc taacaatatt
    45001 ttcattatta aatattgttt tagaagatat tttttaatat aacttatatt ttttataatg
    45061 ttagggtcta atttgtattt ttatttcttc ttaatacgat aagtcctaca atagctccta
    45121 taactaaaag tatttctcca ataattgtag tactatcccc tgtttttggt ggtactggtg
    45181 gatttaccaa agtatcatct ttaactttat tatttttttc ttctgacact gatggcttta
    45241 ctacttctgg tattggaata atctgtttaa caggagtttc tatcatctct tctgatggtg
    45301 gtactggagg attcaatacc tctggtattg gcggatttat tatatcttct gatggtggta
    45361 ctggtggatt tataactata gtatcctctg tatcagatga acttgatggt ttccttggtt
    45421 tatctgtgct tggtggtact ggtggattta ctattggttc atctgtattt ggtggtgctg
    45481 gtggatttac tggtggattt tcttgtctta tgttttctat atttccaata tccactattc
    45541 taccaatatc tttattacca atttcaacct taattttatc cttcagtttt tcatatccac
    45601 ttggagccat tatctccact aaataatatg ttcctggttt ttttacacta gattgaatta
    45661 taccatcttc atcactaact aaatccttaa ctactatatt tccaaatgca tcttctaaat
    45721 tgaacttagc acctgaaagt acatttttat ctaaagcatc cactttttta gcttcaaaag
    45781 tataaccttg cttagtagtc tctactcctg gaggacttga accattaatc tgagccacat
    45841 ttcgtatagt ctccccaact tttacatttg tgaagtttgc atcaaatgta acccaacttt
    45901 gcacaggttc cccttctttt atctgtttaa attcgtattt atttactaat cttattgtat
    45961 tttttccatc tccagcttct tttttaagtt caagattatc agaatatttt atattagata
    46021 tttctagaac tgagtttact tcatctaaaa gatttacttg tcctgcatca taaactccat
    46081 aagttgacat attgattttg tatttaacaa tctggttatc actactgttt aaaacttttt
    46141 tatcaacttc tttttttgcg cttattaatc cagaattttt cttaaagttt atctcatcat
    46201 ttttatcaat tttactatta tttgcatcaa gaacagctct atttatatag ctatcttcaa
    46261 tactaattac ctttaatgta taagctataa aaaactttga ttccacttct tctttactga
    46321 gattaattgt aaatccagtt ataactttat ctacttgccc actttcattt cttttttctt
    46381 ctactttata tgaaatatta ttggcaattt tttctttact ccaaggagtc cagctcccat
    46441 tcattggaac ttctacaact ctaaaatcat gcccagcttc tcctgaagta gttaatctca
    46501 tgccttctgg tatattatct gttataacaa cattacttat tggtgattta tcatcattta
    46561 ttgaaatctg atagtttatt acttgaccaa cttgagtaat atttgttgct cctgaatgtc
    46621 ctttagtaag aagataatca tctcctctat caaatatact tacagtagca tcatcttctt
    46681 gtatcttctt accatcagat tcaatcctag ctacattctt atatttatta ccatgttttg
    46741 catttttgtc actgattcta gccttatact taacagtata cgatttatct atatttccaa
    46801 aattaactga aatagaattt ttactctgtt caatattaaa atcactaact tcttttccat
    46861 cacttgttac tacacttaca gaaccattta tcaatgtcaa tccttcagga agctcatcat
    46921 acaaaataat gtcttttaac tcttcctgct tttcatttac ttgtatactg taatttatat
    46981 ctttattttt aactggcata aatacagtag ttgatttttt tccttcaaca agctttttaa
    47041 gtgttccttt agcatctgga acatccgttt tatctccagg ttttatttct acatctatat
    47101 ctccacttcc actttctatt tttccagtag tttcaatatg tatttttgca ttagtatctt
    47161 catcaacctt tttaacatat gcttccaaac ctattttacc ttgcattaca ctttggccat
    47221 taggtaattc tctaaatgta agtgtatact ctccattact ttctgtttta tcaaagcatt
    47281 cacttgtata atctaaatta actttattga atacatctgg caccttaaaa gttattgaat
    47341 ctcctgcttg tattcctttt gatgttggag tataagttaa attaaatgat atttttttca
    47401 ttgactccgt ttctattgta ttgttattaa tttttacaac aaatccatag tcttcatttt
    47461 cttcattaag ttcttcttct aaaactttca ataaattttc atcttctaat agattatctt
    47521 cctctggagt tttttctgta tttttattgt ctagtggttt ttcatcttct aaagcttgtt
    47581 ctgacttttt attatctgtt gacttatctt cttctggtat ctgctctggc tttttattat
    47641 ctattggctt ttctccttct ggagtttgct ctggcttttt attatctgtt gacttatctt
    47701 cttctggggt ctgttctggt tttttattat ctgttggttt ttcttcctct ggggtctgtt
    47761 ctggtttttt attatctgtt gccttatctt tctctggagt ctgttctggc tttttattgt
    47821 cgctttcctt ctcctctcca gttgatgaat tagttgaacc actttgaatc tgactattct
    47881 ctcctaattc tgaagcataa gatacagttg gatatattgt agacaccacc atacttaaaa
    47941 tcataattaa actaattaat aatgcctttc tatttccttt cttcatgtaa atctcacccc
    48001 tttaggttac ctataattta taatctaatc ttccattaat atcgtatata aagtaatttt
    48061 tactaaaaaa ttatacaaaa aaagctatga aaataaataa atttatattc atagccggtt
    48121 gcaccactga ctcagtatat ccataaggtg cccaataata gaatatactt caacatctct
    48181 ataatatttc ataaaaacaa ttaaaattgc tttatttata ttaaaaatac aattatatac
    48241 ttctattata ttatgcctct atactattgt ctatcctttt tacatttttt accttatgat
    48301 gagattaatt aataattaaa taaaatcctt atctacaaca attacacaat tatattcagg
    48361 atttatctcc ttaactaatt ttgttatatc ttcttttaag tcatcttctg acatgttttt
    48421 ggaaaattcg gaaggattaa ctactatatc aaatattaaa ttcttcttgc ttccttttcc
    48481 aactattcta aaatcatgca tagattttac aagactattt ttcttaagta tttcttcaag
    48541 ttcttttttg gctgacataa cttctttatc ttcaagacat attgggtcca tgtgaattac
    48601 tagatatata tctaattttt cagatatttc tctctctgca gtatctataa tttcatgtat
    48661 ttccattata tctatgttgg atggaatttc tgcatgtata gatgcaatac atctaccaac
    48721 tccatagtta tgaataatta aatcatgtgt acctattata tatttataag ataacaatag
    48781 ctctataata gaatttacca tttcttcatc tggtgcttcc cctaaaagag gatttatagt
    48841 atcttttaca agagagaaac cagcataaag tatcactaat gatactacga taccaacata
    48901 tccatctatg ggaaaattag taaatctagc tacaataaat gatataacta cacaacttga
    48961 agtaaataca tctcctaaag catcaagtga aactgctttt aaggctgaag aatcaatttt
    49021 atttcccata aatttattaa aacgactcaa ccagatttta atcattatag atgcaattaa
    49081 aagtataagt ggtattactt caaattttac aggaattgga tttactatcc tttctataga
    49141 tgactttaca aattgaagtc caaccaacat caccataaat gctactatta atgctgataa
    49201 atactctatt cttccatgac caaaagggtg ttctttatca gctggcttac ttgctaattt
    49261 aaaacctatc atagttattg ctgaagatgc catatcagaa agattattaa atgcatcagc
    49321 cattatagct atactagatg tgagcattcc tatgaatacc tttatcacaa ataaaagtaa
    49381 attggataat atacctacta caccagctac ataaccatac ttatttctaa catctgtatt
    49441 ttgaacgttt tcgctatctc tgataaatgt tttgactagg attttggaaa acatgaaact
    49501 tacctccctg ccctttattt tattaacaaa ttttataatc tatatcttta tttatgataa
    49561 cataatttat atataaaatt cttaaaaatc actctacttc aataaaatat tattctatat
    49621 atctatttag atacgaattt tatatttagt aaagttttta tggcttagtg tctgtttaat
    49681 agattctata taagttttta caaagattat ttattatgat aatatcattt ttcccaagta
    49741 ttacttagaa tatgattttt ttgttttgtc tgtacatatt ttaaatttat actatattta
    49801 cctatatttt ataaccttat gatacactat aactataaga ttttaaatgg aagtgaatga
    49861 aataaatcat gttttttatc agtgatattt acacaaaatc acctattaaa tttgatactc
    49921 ctttgcaaaa agaggcatac aaaatattac aaaaattaga tattgacttt gaatgtgttg
    49981 acacatatga agcaattaca atggaagatt gtgttcagat taataaaaaa ttaaatatga
    50041 aaatggtaat ataaaacaac attaaacaaa caaaaaccgc aaagttacaa tatatagtac
    50101 tttgcggttt cataggaatt aatttttact attaaagttc atagttctac tatttttcat
    50161 tgttctaaga attagcttta caaattcatt tgacaatagg atagtggatg caaatagtat
    50221 tatctttatc cacatatcaa agtccaaaga aacagaatta aagaaactct ggaacacttg
    50281 tgtaaatatt atttgaatta tccctgtaac tactattatt tgcaatgcca gtttattttt
    50341 aaagaaattt ggtattgtac tatttaaacc aaactctcta caatttaatg cattaaaaag
    50401 ggcactgaat gcaaataaag aaaatataac agtaccttgt tcttctgatg tagctcccaa
    50461 tatattaaaa gctgattgag taaatacaat tgtaattata agaatagcat ttataataat
    50521 atttacaaac atagacctag ctattattcc agaatgtcta tttattggtt ttcttttcaa
    50581 tacataatct ctaacaggtt ctaatcctaa tgctagggct ggaggaccat ccattattat
    50641 atttacccat aataattgta ttgtagtaaa tggcatatcc ttaccagtaa gttgagatat
    50701 tatagcaatt ataaatgcta ctatatttac agtaagctga aactgtataa atctttgaaa
    50761 gttctcatat atacctcttc cccattttat tccctctact atagtactaa agctatcatc
    50821 agtcaatatt atatctgctg catttttaga tacttctgtt cctgaaatac ccattgcaat
    50881 tccaacatct gcttgactaa gtgctggggc atcatttata ccatcacctg ttacagctac
    50941 aacttcgcca cttttttgaa gtgctgaaac tattctcatt tttgtatctg gtttacttct
    51001 tgcaacaata gatattcctt tgatttcttc tctcaattct ttatctgtca atacatctat
    51061 atatgttgct tcaactgcct ttttcccatc atttaataat cctaattcat ttccaatagc
    51121 tgttgctgta tttatattat ctcctgtaag catttttaca tctactcctg cattaaatgc
    51181 tttatcaatg gaatctttga ccccttctct caatgggtcc actattccta caaatccact
    51241 aaaaactaaa ttttcttcct tcatataact tcttgaattt cctattaaat tcaattcacc
    51301 ttctgaagtc attgcaactt ctgttttaga attactcatt tttttataag caaatcctaa
    51361 tgttctcata gatttaattt gtaacttctt aatctcatct aaaatacttt tttctacttt
    51421 tggagttatt ggaacaatat tttttccttg ttgtacataa gaacattttt ttaataatac
    51481 ttctggagca ccttttgaaa gtaatatatc tgaatcctct tgacgaatta atgttgacat
    51541 cttcttttct tctgaactaa atggtatttg tgatatcaaa tacgtttgtt ttctcatttc
    51601 attatagttc ttatcattat gatataaaag taatgcacac tctgttgcgc ttcctatata
    51661 tttaaatgaa ttatcttctt tttctatatc tgcagttgaa tttactatac agttttgttc
    51721 aaaatagcta ttactttgat actctcctcc acttatatat ttaccatcaa catatgctac
    51781 ctctaccatc attttgtttt gtgttaaagt ccctgttttg tcggaacata ttacagaaac
    51841 agaacctata gtttcacagg cttctttctt tgttactaat gcatttatct ttgccatctt
    51901 ttgcattgtt atagctaagg taatatttat catagttggc aaaccttctg gaacagttgc
    51961 aactattaat gcaatacaaa ccatatatgc atttttagca ggttctaatg attgtaagaa
    52021 agataataca ctgcttgtat ctaaaattaa catacctttt ctctgcatct gtataatcat
    52081 aaacatacac aataaagtag ctattatgcc tgatattcct gctattttag cacccaactt
    52141 ccctaattta atttgaagtg gagtttgctg gtcttcattt gataaattct gtgctatctt
    52201 acccatctct gtcttatcac cagtatgagt gacaaccatt atgcccctac catatgctac
    52261 aagagtccct ccaaatacca tattgacttg ctttgcaggt attgcatcct gttcgattat
    52321 ttctgtttta gaataaacta cttccatatc taatacagca tcagcattct tagctacatc
    52381 atcagattct cctgttagca tatcttctct aagtttcaaa tttatagact gtataagtct
    52441 tccatctgct ggtatcatat ccccagtttc tatatataca atatctcctg gtactaaatc
    52501 attttttgat attttaatta tcttcccatt tctaagtacc tttacttcta tattttctgt
    52561 taattttgac agtgcatgag ctgctttttt agattttcct tcagttatta tgcctataga
    52621 aattccaata aaaatagccc ctaaaatacc taatgcgtca tgtaattctc ccacaaaaga
    52681 acttattact gctgctccta tgagaattaa tatcataggt tctgtcaaac tttctcccaa
    52741 ctcgtcccaa aatgttctac cttcttttat agtaaattca tttaatccat atctaagctt
    52801 cctttcttct acctcattat catcaagtcc aatttctgga tttgttttta agtattttaa
    52861 tacttctttg gtaggtttat tataatacct cataacttta tcccccttgt taattatcta
    52921 taaggaatta tatgcttatg atagcttgta tattactttt caaaaaaaat aaggtgttga
    52981 ttaatcaaca ccttatagtg attatatatt attaaatttt atgttacagg ctttataaat
    53041 tgtgagctat acaaatcaaa atatttaatc ttcaaaatac ccttctggat ataatggaaa
    53101 cttagatata agttcttgtg cctctgcttt acattcatct aatacttctt tattatcaat
    53161 attttctgct accttattca ttatccctgc tatctgtata acttcttttt ctttcagacc
    53221 tctttgagat attgatgtaa gacctatacg aacaccacta gttacaaatg gtgattgtgg
    53281 gtcgtcaggt ataacatttt tattaactgt tattcctaca tattcaagag ctttttcaaa
    53341 ttgttttcct gtaagattct tacttcttaa gtcaaccatt actatatgat tatcagtacc
    53401 tccacttaca atactaaaac catgtgaaat cagttcagaa gctagagtct gagcatttac
    53461 tacaacttgc tccattatct ttttaaattt atctgtactt aaatataata gtgaaaaggc
    53521 ttttgctgca actgtattaa gatgtataga ccctaatgtt cctggaaaaa cacctttatc
    53581 gagtttcttt gcatgttctg ctttacaaag tacaatacca cttcttggtc cacagaaagt
    53641 ctttgtcgta gatgaagaaa caaaatctgc ataaggtaca ggactaggta ttactttcgc
    53701 tgcgactaat cctgcaacat gtgccatatc taccataaag taagctccta cttcttttgc
    53761 aacctttgat attctttcat aatctattaa tcttggatat gaacttgccc ctgcaattat
    53821 aagttttggt ctacattctt ttgcctttgc ttcaagagca tcataatcta tacgtccagt
    53881 atttgggtct accccataaa attcatattt ataaatgtca tgtaaaaaat taactgcgct
    53941 accatgtgtc aagtgtccac cttggtcaag acgcatactt aaaacagtgt catttggttt
    54001 taatattgat gaatatacac aatagttagc tgtagaacct gaatacggtt gtacgtttac
    54061 atgttctgct ccaaatactt cttttgcacg ttttattgct agggtttcaa gtttatctgc
    54121 ttcttcagaa cctgcttgaa aacgagcccc tggatagcct tcttctgttt tatttgtaaa
    54181 tacacatcca cttaattcaa gtacttctgt tggtgctgta ctttcagaag ctatcatctc
    54241 aatattgtgt tcttgtctaa ccaactcatc agctacaatc ttgtataact ctgggtctga
    54301 aatttttgtt gtttttaaca taataatcct cctcttaatt aaagaatata ttttattagt
    54361 ttaatcttca ttgataaatt tattataacg gtctataaaa cgtaagatat tcctccacca
    54421 ggtcctaatg gtatgccaat acccatgaat agtaacaata ttattatttc tattaatgta
    54481 aataccactg agtatggaat catattcgat atgacagtac ctatacctat atctttatca
    54541 tatcttctgg caaaggccaa tataactgga aaatacggaa aaagtggact tattggattt
    54601 gttgaagcat ctccaatacg ataagctatt tgagttaatg ctggattaaa gtctagtagc
    54661 ataaacatgg gaacaaatat aggtgctaaa atcgcccatt ttgcagaagc acttcctaca
    54721 aataaattga taaatccaga tagcaatata aatcctatta tcaatccata gctaggtatc
    54781 cccgactctg ctagtaattt tgctcctgtt attgataaaa ttgttcctaa gttactaaga
    54841 ttaaataaat taataaactg ggatgctata aatgctagga ctatatatcc acccatatca
    54901 ctcatactac tacccatcat agatactaaa tctttgtcac tttttatctt cttacttact
    54961 tttccataca ctaatcctgg agttaaaaat ataatagtga ttataggaac tatacctttc
    55021 attaaaggtg cattactaga tagtatagaa ccagtctctg gatctttcat aaatgcattg
    55081 tcacctatac ataaggcaac tatcactact actacaacta acaatgataa taaagcgtat
    55141 tttataccct tattttcaag ttcactcaat tcctgtatat ccttatcatt tgttgaatca
    55201 ttatattttg taaaacgagg agctataaat ttttcagtta caaatgctcc tgcaaaagtt
    55261 aaaactatcg ctgatataaa agtaaaataa agattcattg ctggattgcc ttggtaagat
    55321 gggtccatca tttgagctgc tggtattgta aatccagcta acaatacatc tgtagtacta
    55381 agcataacat ttgctgcaaa tccccctgca acacctgcaa aagctgcaaa catacctaca
    55441 agaggatgtc ttccaattcc taaaaacaca agtgctgcaa gtggtggtaa tattataaat
    55501 cctacatctg ctgctgtatg tgacaacata cctgcaaata cgattgctac agttacaagt
    55561 ttttgtggaa ctttacttat accctttttc attaacactt ccataaatcc agatttctca
    55621 gcaacacctg ctccaagcat tgtaaccagt actaatccta aaggagcaaa tgactgaaag
    55681 tttgtaacta tgctacctaa atatgattga atctgctctt tctctagtag atttactacc
    55741 tttacaactt cttttgtaga aggatgtatt tcttctactc ctaaattaga tataactgct
    55801 gacaatatta caacaattat acatagtaat aaaaatatgg ttactgggtc tggaagttta
    55861 ttccctgctc tctctacaac atttagtgcc ctcatcaata atccactatc tttgtttttt
    55921 tcctgtgaat taattttcct caaactaata ccccctcata aactttatct ccagaatgct
    55981 ctatcttaaa ttttattttt taatttatcc atataattta taacagactg acatagtaca
    56041 tttgtaccta ctaatataga atttttatca gctttaaatt taggattatg ccactgatat
    56101 atacaatctt gttctttgtt gcctacccct aaccagtaaa aaaatcctgg ggctttttcc
    56161 atgaatatag aaaaatcttc tcctcctgta gaaggtattg gatcaactat agcatcttct
    56221 gaatacaaat cacacacaga cttacaagct attgcgtaca tctctttact atttataaca
    56281 gctggtaaat caaataaata atctagcttt gcagttgctt gatatccatg agctatctca
    56341 caaactatat tttctaaatt ttctgatatt ttctttcgta cttcattact aaagcttcta
    56401 catgtgcctg tcatatctac cttttctgaa attacattat ttgcagtccc tccatttata
    56461 gtacctattg atataacagc tgattctaat ggacttatgt ttctgcttac tatggtttga
    56521 atacccatta taattgcact tgatgctact atagggtcta ttgttctgtt gggtatacct
    56581 ccgtgacctc caaatccatt tacttctatc ttaatagtgt ctactgctgc cattaaccca
    56641 cctaacttaa cacctatttt tccacaaggt atatctggat gattatgaag tccaaatata
    56701 gcatcaactt ttggattttc cattactcct cgttccacta gcatcttcgc acctttattg
    56761 acttcttcgg ctggttgaaa tataaacttt acatttccat gaagactatc tctaatatga
    56821 gacaatacat atgcacatcc tacaaggcaa gacgtgtgta tatcatgccc acatgcatgc
    56881 attataccat catatctgga tttatactta atatcaacct cttcatatat tggcaatgca
    56941 tcaatatctc ctcttagtgc tactgtggga ccatcatact tcccttttaa taatccaaca
    57001 acgcctgttt ccattcctaa atctaatatt tctatgtcta aacttactaa taaatctttt
    57061 atagcttttg tagtcctaaa ttctttaaaa cttaattcgg ggtgcatatg aatatctgta
    57121 aaaaaatcta aaatatcttc tttatacttt tctgagatta aaataagttc atgcatacta
    57181 acacctctcc aaaattttat ttttttattt tttataattt aacta
//
LOCUS       DAEPUT010000015        56436 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.015, whole genome shotgun sequence.
ACCESSION   DAEPUT010000015 DAEPUT010000000
VERSION     DAEPUT010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56436
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.015"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            55..171
                     /gene="rrf"
                     /locus_tag="KRL22_001047"
     rRNA            55..171
                     /gene="rrf"
                     /locus_tag="KRL22_001047"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            179..253
                     /locus_tag="KRL22_001048"
     tRNA            179..253
                     /locus_tag="KRL22_001048"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Asn,seq:gtt)
     gene            259..344
                     /locus_tag="KRL22_001049"
     tRNA            259..344
                     /locus_tag="KRL22_001049"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:293..295,aa:Leu,seq:taa)
     gene            360..435
                     /locus_tag="KRL22_001050"
     tRNA            360..435
                     /locus_tag="KRL22_001050"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:393..395,aa:Met,seq:cat)
     gene            443..517
                     /locus_tag="KRL22_001051"
     tRNA            443..517
                     /locus_tag="KRL22_001051"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Glu,seq:ttc)
     gene            532..605
                     /locus_tag="KRL22_001052"
     tRNA            532..605
                     /locus_tag="KRL22_001052"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:564..566,aa:Gly,seq:tcc)
     gene            611..686
                     /locus_tag="KRL22_001053"
     tRNA            611..686
                     /locus_tag="KRL22_001053"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:644..646,aa:Val,seq:tac)
     gene            692..768
                     /locus_tag="KRL22_001054"
     tRNA            692..768
                     /locus_tag="KRL22_001054"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:726..728,aa:Asp,seq:gtc)
     gene            779..853
                     /locus_tag="KRL22_001055"
     tRNA            779..853
                     /locus_tag="KRL22_001055"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:811..813,aa:Gly,seq:gcc)
     gene            863..936
                     /locus_tag="KRL22_001056"
     tRNA            863..936
                     /locus_tag="KRL22_001056"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:897..899,aa:Arg,seq:tct)
     gene            1920..2759
                     /locus_tag="KRL22_001057"
     CDS             1920..2759
                     /locus_tag="KRL22_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBH1271560.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            2756..3937
                     /locus_tag="KRL22_001058"
     CDS             2756..3937
                     /locus_tag="KRL22_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271561.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            4241..5143
                     /gene="ptb"
                     /locus_tag="KRL22_001059"
     CDS             4241..5143
                     /gene="ptb"
                     /locus_tag="KRL22_001059"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HBH1271562.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            5165..6244
                     /gene="buk"
                     /locus_tag="KRL22_001060"
     CDS             5165..6244
                     /gene="buk"
                     /locus_tag="KRL22_001060"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH1271563.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIKDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            6234..6911
                     /locus_tag="KRL22_001061"
     CDS             6234..6911
                     /locus_tag="KRL22_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1271564.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6954..7169
                     /locus_tag="KRL22_001062"
     CDS             6954..7169
                     /locus_tag="KRL22_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1271565.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            7198..8277
                     /locus_tag="KRL22_001063"
     CDS             7198..8277
                     /locus_tag="KRL22_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH1271566.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            8277..9029
                     /locus_tag="KRL22_001064"
     CDS             8277..9029
                     /locus_tag="KRL22_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH1271567.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            9030..9587
                     /locus_tag="KRL22_001065"
     CDS             9030..9587
                     /locus_tag="KRL22_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH1271568.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            9757..11103
                     /locus_tag="KRL22_001066"
     CDS             9757..11103
                     /locus_tag="KRL22_001066"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBH1271569.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            11370..13202
                     /gene="glmS"
                     /locus_tag="KRL22_001067"
     CDS             11370..13202
                     /gene="glmS"
                     /locus_tag="KRL22_001067"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBH1271570.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     QNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            13654..14949
                     /locus_tag="KRL22_001068"
     CDS             13654..14949
                     /locus_tag="KRL22_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HBH1271571.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYLDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            15426..16163
                     /locus_tag="KRL22_001069"
     CDS             15426..16163
                     /locus_tag="KRL22_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HBH1271572.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            16184..17437
                     /gene="murA"
                     /locus_tag="KRL22_001070"
     CDS             16184..17437
                     /gene="murA"
                     /locus_tag="KRL22_001070"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBH1271573.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            17524..18588
                     /gene="spoIID"
                     /locus_tag="KRL22_001071"
     CDS             17524..18588
                     /gene="spoIID"
                     /locus_tag="KRL22_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HBH1271574.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKAESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            18654..19322
                     /locus_tag="KRL22_001072"
     CDS             18654..19322
                     /locus_tag="KRL22_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HBH1271575.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            19420..19680
                     /gene="spoIIID"
                     /locus_tag="KRL22_001073"
     CDS             19420..19680
                     /gene="spoIIID"
                     /locus_tag="KRL22_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HBH1271576.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            19877..20896
                     /locus_tag="KRL22_001074"
     CDS             19877..20896
                     /locus_tag="KRL22_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH1271577.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            20912..21340
                     /gene="fabZ"
                     /locus_tag="KRL22_001075"
     CDS             20912..21340
                     /gene="fabZ"
                     /locus_tag="KRL22_001075"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBH1271578.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(21451..21960)
                     /gene="yyaC"
                     /locus_tag="KRL22_001076"
     CDS             complement(21451..21960)
                     /gene="yyaC"
                     /locus_tag="KRL22_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBH1271579.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      22149..22252
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            22388..23581
                     /locus_tag="KRL22_001077"
     CDS             22388..23581
                     /locus_tag="KRL22_001077"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBH1271580.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            23897..24994
                     /locus_tag="KRL22_001078"
     CDS             23897..24994
                     /locus_tag="KRL22_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271581.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            25258..27477
                     /locus_tag="KRL22_001079"
     CDS             25258..27477
                     /locus_tag="KRL22_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBH1271582.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            27480..28262
                     /locus_tag="KRL22_001080"
     CDS             27480..28262
                     /locus_tag="KRL22_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBH1271583.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            28594..30507
                     /locus_tag="KRL22_001081"
     CDS             28594..30507
                     /locus_tag="KRL22_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1271584.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            30648..30956
                     /locus_tag="KRL22_001082"
     CDS             30648..30956
                     /locus_tag="KRL22_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1271585.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            30980..31306
                     /locus_tag="KRL22_001083"
     CDS             30980..31306
                     /locus_tag="KRL22_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1271586.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            31345..32679
                     /gene="celB"
                     /locus_tag="KRL22_001084"
     CDS             31345..32679
                     /gene="celB"
                     /locus_tag="KRL22_001084"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBH1271587.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKILDKQYLREENETVEEEDDDISFDDLVL"
     gene            32690..33208
                     /locus_tag="KRL22_001085"
     CDS             32690..33208
                     /locus_tag="KRL22_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBH1271588.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            33304..34263
                     /locus_tag="KRL22_001086"
     CDS             33304..34263
                     /locus_tag="KRL22_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HBH1271589.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCVATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            34312..35364
                     /locus_tag="KRL22_001087"
     CDS             34312..35364
                     /locus_tag="KRL22_001087"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBH1271590.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            35367..36041
                     /locus_tag="KRL22_001088"
     CDS             35367..36041
                     /locus_tag="KRL22_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBH1271591.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNNIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     INIISR"
     gene            36593..37144
                     /gene="raiA"
                     /locus_tag="KRL22_001089"
     CDS             36593..37144
                     /gene="raiA"
                     /locus_tag="KRL22_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH1271592.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            37276..39951
                     /gene="secA"
                     /locus_tag="KRL22_001090"
     CDS             37276..39951
                     /gene="secA"
                     /locus_tag="KRL22_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH1271593.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            39966..41073
                     /gene="prfB"
                     /locus_tag="KRL22_001091"
     CDS             join(39966..40040,40042..41073)
                     /gene="prfB"
                     /locus_tag="KRL22_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBH1271594.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            41217..43358
                     /locus_tag="KRL22_001092"
     CDS             41217..43358
                     /locus_tag="KRL22_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBH1271595.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIREI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            43506..44672
                     /locus_tag="KRL22_001093"
     CDS             43506..44672
                     /locus_tag="KRL22_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1271596.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKALGIEDRVGSIEIGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      44732..44849
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            44974..45579
                     /locus_tag="KRL22_001094"
     CDS             44974..45579
                     /locus_tag="KRL22_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1271597.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            45908..46948
                     /locus_tag="KRL22_001095"
     CDS             45908..46948
                     /locus_tag="KRL22_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH1271598.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMESVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSIQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            47087..47539
                     /gene="tsaE"
                     /locus_tag="KRL22_001096"
     CDS             47087..47539
                     /gene="tsaE"
                     /locus_tag="KRL22_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBH1271599.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            47539..48255
                     /gene="tsaB"
                     /locus_tag="KRL22_001097"
     CDS             47539..48255
                     /gene="tsaB"
                     /locus_tag="KRL22_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBH1271600.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVDFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            48245..48721
                     /gene="rimI"
                     /locus_tag="KRL22_001098"
     CDS             48245..48721
                     /gene="rimI"
                     /locus_tag="KRL22_001098"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBH1271601.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            48727..49743
                     /gene="tsaD"
                     /locus_tag="KRL22_001099"
     CDS             48727..49743
                     /gene="tsaD"
                     /locus_tag="KRL22_001099"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBH1271602.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREILSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            50040..52748
                     /gene="hpdB"
                     /locus_tag="KRL22_001100"
     CDS             50040..52748
                     /gene="hpdB"
                     /locus_tag="KRL22_001100"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HBH1271603.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            52752..53009
                     /gene="hpdC"
                     /locus_tag="KRL22_001101"
     CDS             52752..53009
                     /gene="hpdC"
                     /locus_tag="KRL22_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HBH1271604.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            53002..53952
                     /gene="hpdA"
                     /locus_tag="KRL22_001102"
     CDS             53002..53952
                     /gene="hpdA"
                     /locus_tag="KRL22_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HBH1271605.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWTQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            54267..55229
                     /locus_tag="KRL22_001103"
     CDS             54267..55229
                     /locus_tag="KRL22_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1271606.1"
                     /translation="MNKSWSNLIIKNKDRKVRSGWIIIAVMTTFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(55328..56308)
                     /locus_tag="KRL22_001104"
     CDS             complement(55328..56308)
                     /locus_tag="KRL22_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1271607.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFGLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEVPILGIILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT        22618 a         6094 c        10680 g        17044 t
ORIGIN      
        1 ctaggttcta taaacttatt aaaaacttaa tagaaatatt aagcataaag attatgtggt
       61 tacaatagca gagaggatac acctgttccc attccgaaca cagaagttaa gctctctagc
      121 gctgatggta cttggtggga aactgcctgg gagagtagga cgtagccacg ttaaatgttc
      181 caaggtagct caacggtgga gcaaccggct gttaaccggt aggctgtggg ttcgagcccc
      241 acccttggag ccaaaaaagc cgaagtggcg gaactggcag acgcacagga cttaaaatcc
      301 tgcgggactt acctctcgta ccggttcgat tccggtcttc ggcacttata aaacaatatc
      361 gcggggtgga gcagttggca gctcgtcggg ctcataaccc gaaggtcgta ggttcaagtc
      421 ctgcctccgc aaccattaaa acggctcgtt ggtcaagagg ttaagacact gccctttcac
      481 ggcggtaaca ggggttcaat tcccctacga gtcaccaatt caattaaata tgcgggtgta
      541 gctcaatggt agagttctgg ccttccaagc cagctgtgag ggttcgatcc ccttcacccg
      601 ctccaaaaat gggaccatag ctcagctggg agagcacctg ccttacaagc agggggtcac
      661 aggttcgagc cctgttggtc ccaccattcg cggcctggta gttcagttgg ttagaatgcc
      721 agcctgtcac gctggaggtc gagggttcga gccccttcca ggtcgccaaa ttaaataagc
      781 gggaatagtt cagtggtaga gcgcaacctt gccaaggttg aagtcgcgag ttcgaatctc
      841 gtttcccgct ccataataac ttgggtgcat agctcagctg gatagagcaa cgcccttcta
      901 aggcgtgtgt ccggggttcg aatccctgtg cgctcattaa gaaaagttta ctataaatta
      961 tagtaaactt ttatattgtt taaaaagaca caggaaacat gtatattacc tgtgtctttt
     1021 tatttataaa ctttaaacta tgtaaaaatt acagtatatt ctaatagagt tacagtatat
     1081 tcattaatat tgtaaacata cggagggtaa tgtataatag tctacaagat gtttatgaag
     1141 gcatcagtta aatataataa atataactaa ttagtaagag ttatatacat tatattgtat
     1201 actttatggt atttatatat tgaaataact tatgaagtta tttataaaga gattcatgag
     1261 catatttttg tctaaacaat aagtataaga aattataaaa aattagagac tatagtgaat
     1321 ttacaattta atgtaatatt tataagttat actaaataaa ttattatact gtgaaatgga
     1381 tatataactt taggtattgt gtattatttt cactgtagga gattatatct agttatacat
     1441 aataagtttt aatgatagtt tatagtaaga tattaaaata aatttatcta atctagatat
     1501 gaaataagtt attactttaa tataaaaatg aacctaatgg aataatattg atgataagta
     1561 atatttagat tttgtatttg tttatagtta ataagtggat tatagaattt ataataatta
     1621 atatatatta aacaaagata tattaagata ttttagaaca caaaactgca ttaaggcgcg
     1681 agtactattt tgtattcgcg ccttgatggt ttgagttatt tgagtaaaaa ctaactttaa
     1741 taagaaatct gtatttatta agttgatatt tttaatgtgt ttagagatta tttaacaatc
     1801 tccaaatata aaactagaat tatttacata aaagttaaat agtttgtata gagttagatt
     1861 tatatagtat aatacttagt gtaaataatt aagaagttat caaacaggag gataaaactg
     1921 tgttagatat aaattctttt ttaaatggat tttttaatat aatattaaga atgagtatat
     1981 atgatttaat tgacatatct atagtagcgt atatttttta caaaatattt atgtttataa
     2041 aagatacaag agcagaacaa gtgtttaaag gtataatatt tcttttatta gcaactcaac
     2101 ttagtaacac ctttaaattg cataccgttt attggatatc tcttaaagct ttagattatg
     2161 gagttatagc tgctcttata atttttcaac cagaatttag agcaggactt gaacatatag
     2221 gaagagcaaa gtttaattta tttggaaaga atgtaaatac ttctgaagaa actctcaata
     2281 gaaatataga agaaattgta gaagctttat attcactttc tagacaaaaa ataggagctc
     2341 ttatcataat ggaaagagaa actagaataa gtgatataat aaatacagga actattattg
     2401 atgctgaaat ttctaggcaa ctattaataa atatatttat accaaataca ccattacacg
     2461 atggagctgt tgtaattaga gattctaagg taaaagcagc tgcatgtttt ttgccattga
     2521 cagaaagtaa ggatttaagt aaagatttgg gtactagaca tagagcagga ataggggtaa
     2581 gtgaggtgtc tgactgtata actttgattg tatcagagga aacaggtggc gtatcaattg
     2641 ctaaagcagg taagttatat agagatattt ctagagaaag aatgatgaat atattacgta
     2701 gtaatttaaa aacaaataca gaaacaagaa gttttttcaa aggtggtata tttaaatgat
     2761 aaatagacta aaaaataata ccaaaataaa aataatatca tttttaagtg caattgcatt
     2821 atggatgtat gttatggctg tagttgaccc tgaagaaact aaagggtttg aagatatacc
     2881 tgtatctata agtaatatga gtgatttaaa ggataaaaat cttgttatat atccagacga
     2941 aaaattaaca gcagatgtat atataaaagg tagtttatca aaggtacaaa gtgttaaaaa
     3001 agaagatata catgtatatg gaaccattga agacccaata caaggacaga aggaagtata
     3061 tttaaaagca aatattcctc aaggtgttac tctagaattt aagcatgatg ttttagtagt
     3121 aaatcttgaa aaaaacataa aagaaaaaag agatataaag gtagaagtaa gtggaaattc
     3181 aaaaagaaat ataaataaaa ttgaacttag taaggaattt gtcgatgtat caggtccaag
     3241 aactctagtt aaagaagtca aaagtgtaag agctaatcta gatgttggta atgagacaga
     3301 tgatttttct aaaaaattgc aattaatacc attaaatagt gatggaacta aggttgaagg
     3361 agtaacatta agttcatcct ttgtgactgc aaagatagaa ctattgaagg aaaaaattgt
     3421 cccaataaga gtaagtctaa atgataataa agataatgat gtactgaaaa actataaatt
     3481 aagtaaggaa caagttacaa taaaaggaaa gaaagaagat atagacaaaa taagttatat
     3541 taagacaaaa cctattgact tagctgattt ggctaatggt gaagaaaaag aagttagctt
     3601 agaaattcca gagggtataa ctcttgagga tagctctata acaattaaat taaatgatac
     3661 aaaacaattg agtgcagaat ttttatataa tgcgggagat attgaattaa gaaatatccc
     3721 aacaaatatg gataatccaa atgtaatttc tgatgtagat ataaaagttg ttgtagagtc
     3781 aacggaggat ttgagtaagt taaataaaaa agatatttca ttatatattg atttatcaca
     3841 aggccctgag gaagatagta aatataaaat aaaatatgaa acaacatatc aatttaaaaa
     3901 aataaatata gaacctaata ttgttgaagt ggaatgaaca aatatttcga atatttagtt
     3961 gttacaagat gcgacaaaaa aacctataaa attaagtttg ttaattttat gtttttgttg
     4021 catcttgttt attttagtta tattataaaa taaggacaat gagatatttg ttaaatctaa
     4081 aaagcgctag atatatgaaa aaagactgat aaatagattt aaataaatat tttgaattaa
     4141 atatttcaat tatctctagg aaaacgttgc tgaacgagtt ataatttaat tgagatataa
     4201 aaagttctat ttcaaaaaat tcaagatgag gtggaaatgc atgagaagtt ttgaagaagt
     4261 aattaagttt gcaaaagaaa gaggacctaa aactatatca gtagcatgtt gccaagataa
     4321 agaagtttta atggcagttg aaatggctag aaaagaaaaa atagcaaatg ccattttagt
     4381 aggagatata gaaaagacta aagaaattgc aaaaagcata gacatggata tcgaaaatta
     4441 tgaactgata gatataaaag atttagcaga agcatctcta aaatctgttg aattagtttc
     4501 acaaggaaaa gccgacatgg taatgaaagg cttagtagac acatcaataa tactaaaagc
     4561 agttttaaat aaagaagtag gtcttagaac tggaaatgta ttaagtcacg tagcagtatt
     4621 tgatgtagag ggatatgata gattattttt cgtaactgac gcagctatga acttagctcc
     4681 tgatacaaat actaaaaagc aaatcataga aaatgcttgc acagtagcac attcattaga
     4741 tataagtgaa ccaaaagttg ctgcaatatg cgcaaaagaa aaagtaaatc caaaaatgaa
     4801 agatacagtt gaagctaaag aactagaaga aatgtatgaa agaggagaaa tcaaaggttg
     4861 tatggttggt ggaccttttg caattgataa tgcagtatct ttagaagcag ctaaacataa
     4921 aggtataaat catcctgtag caggaagagc tgatatatta ttagccccag atattgaagg
     4981 tggtaacata ttatataaag ctttggtatt cttctcaaaa tcaaaaaatg caggagttat
     5041 agttggggct aaagcaccaa taatattaac ttctagagca gacagtgaag aaactaaact
     5101 aaactcaata gctttaggtg ttttaatggc agcaaaggca taattttaag ggggaaatag
     5161 gcaaatgagc aaaatattta aaatcttaac aataaatcct ggttcgacat caactaaaat
     5221 agctgtattt gataatgagg atttagtatt tgaaaaaact ttaagacatt cttcagaaga
     5281 aataggaaaa tatgagaagg tgtctgacca atttgaattt cgtaaacaag taatagaaga
     5341 agctctaaaa gaaggtggag taaaaacatc tgaattagat gctgtagtag gtagaggagg
     5401 acttcttaaa cctataaaag gtggtactta ttcagtaagt gctgctatga ttaaagattt
     5461 aaaagtggga gttttaggag aacacgcttc aaacctaggt ggaataatag caaaacaaat
     5521 aggtgaagaa gtaaatgttc cttcatacat agtagaccct gttgttgtag atgaattaga
     5581 agatgttgct agaatttctg gtatgcctga aataagtaga gcaagtgtag tacatgcttt
     5641 aaatcaaaag gcaatagcaa gaagatatgc tagagaaata aacaagaaat atgaagatat
     5701 aaatcttata gttgcacaca tgggtggagg agtttctgtt ggagctcata aaaatggtaa
     5761 aatagtagat gttgcaaacg cattagatgg agaaggacct ttctctccag aaagaagtgg
     5821 tggactacca gtaggtgcat tagtaaaaat gtgctttagt ggaaaatata ctcaagatga
     5881 aattaaaaag aaaataaaag gtaatggcgg attagttgca tacttaaaca ctaatgatgc
     5941 tagagaagtt gaagaaagaa ttgaagctgg tgatgaaaaa gctaaattag tatatgaagc
     6001 tatggcatat caaatctcta aagaaatagg agctagtgct gcagttctta agggagatgt
     6061 aaaagcaata ttattaactg gtggaatcgc atattcaaaa atgtttacag aaatgattgc
     6121 agatagagtt aaatttatag cagatgtaaa agtttatcca ggtgaagatg aaatgattgc
     6181 attagctcaa ggtggactta gagttttaac tggtgaagaa gaggctcaag tttatgataa
     6241 ctaatgataa aagaataaga atcataactg gtcactatgg aagtggtaaa agtgaatttg
     6301 cgatgaacta tgttgttaag ttaagagata tggtttctgg caaagttgct atagccgatt
     6361 tagatgtggt aaatgtatac tttagaacta gagaaaagaa agagttaatg aaatccttag
     6421 gtatacaacc aatagatagc tcaattaatg ctccaacatt agatttacca gcagtatcag
     6481 cagaggtaat gtctcctatg gtagaccatt catacaattc tgttatagat ttaggtggag
     6541 ataatgtagg tgctagggtt ataggaagat ttagtcattt gttaaaagaa ggcgattatg
     6601 atatgctttt tgtaataaat gcaaataggg agaaaactca aacttctgaa gaagttatcc
     6661 aatatataaa agaaatagaa aaatcttcta aattaaaggt aacaggtcta attaataata
     6721 ctcatcttat taggtttact actattgatg atgttttaag aggtcagaaa gttgcaaaag
     6781 aagtttctga aaaatgtaat ataccgataa gatatgttgc atgtttagaa aatcttgttg
     6841 aacagttacc aaaagattta gaaggagaaa tttttcctat aaaattatat atgagagaag
     6901 actggatgta gtttgagctc aaatatatag aaagtttaag gaggcttagg taaatggcta
     6961 aaggaaaagt atcttttaat caagaacgtt gtaaaggttg tggattgtgt gttgaagcat
     7021 gtccagtaaa aatcatacaa ttagactcaa atgtaataaa caaaaaaggg tataacccag
     7081 caactgtttt tgaaatggaa aaatgcatag gatgtgcaag ttgtgcaact atgtgtccag
     7141 atgtagttat aacagtagaa agagattaat ttaattaata tttaaggggg aattttaatg
     7201 gctaagatac ttatgaaagg taacgaagca tttggaaaag cagctataga agctggttgc
     7261 aaatatttct tcggttaccc aataactcca caaagtgaat taccagaata tttatcaaga
     7321 gagttaccta aaataggtgg agcgttcgtt caagctgaat cagaagtttc tgcgataaac
     7381 atggtttatg gtggagcagg tgcaggagca agagttatga cttcttcatc ttcaccagga
     7441 gttgctttaa agcaagaagg tataacatat gcagtaggag cagaagttcc ttgtgttgta
     7501 cttaatgtaa tgagaggtgg tccaggactt ggaagtatac aaccttcaca agctgactac
     7561 tttatgtcta caagaggtgg aggaaatgga gactacagaa ctccagtatt cgcaccagct
     7621 acagttcaag aagctgttga tatgataatg gaagcttttg acgttgcaga ttattacaga
     7681 tcaccagtta tggtagttgc agatggtatg ataggtcaaa tgatggagcc agttgaattt
     7741 agagctcctg agaagaaaag agaattgcct cctaaagatt gggcaactgt tggaactaaa
     7801 ggaaaaagaa aacctaatgt aataaactct ctatacttag agccagaagt actagaagac
     7861 cattgttggc atttacaaga aaaatttgat gcaatggaaa agaatgaagt acaatacgaa
     7921 atgtacaaaa cagaagatgc tgaatttgta tttgcagctt atggaactac ttcaagagta
     7981 gtaaaaagcg caattgatat attaagagaa gaaggaataa aagcaggtct tataagacct
     8041 aaagtattat ggccattccc attcgaagca ttcaaccaaa ttcctaatgc tagaaacata
     8101 ttgactgttg aaatgagtat gggacaaatg gtggaagatg ttaaaatggc agtagaaggt
     8161 aaattaccag tttacttcca tggaagacca ggaggaatga ctccaacacc agcagaaata
     8221 gttgaaaaag ctaaaaaaat tattgccgga gaattggttg caggaggtgc tagataatgg
     8281 ctgttgtatt taagaaaact gaaggattac aagatactca aactcactac tgtccaggat
     8341 gtacacatgg tataatccat agattagttg gtgaagtatt agaagaacta ggagtattag
     8401 gtgatgctgt aggtgttgtt ccagttggat gttcagtttt aggatataaa tattttaact
     8461 gtgacactca agaagctgct catggtagag cgccagctgc tgctacagga ataaaaagag
     8521 ttcatcctga aaatacagta ttcacttatc aaggtgatgg agacttagct tcaattggta
     8581 ctgctgaaat agttcatgca gctgctagag gagaaaaaat aactactata tttgtaaaca
     8641 atacaactta tggtatgact ggtggacaaa tggctccaac tacattagtt ggacaaagag
     8701 ctactactgc tcaatcagga agaaatgctg aaactcaagg ttatccaata agagtaagtg
     8761 aaatgttagc tacattaaca ggagctgtat ttgtagaaag agtagcagtt gatactccag
     8821 ctcatgttag acaagctaaa aaagctataa agaaagcatt ccaagttcaa caagcaggat
     8881 taggatttgg aatagtagaa gtattatcta cttgtcctac aaactgggga ctagctccaa
     8941 atgatgcttt acaatggtta agagacaaca tgataccata ctatccatta ggaaatttca
     9001 aaaatgttga agttgaggag gtgaagtaaa tgtctacagc tagagtaata tgtgcaggct
     9061 tcggaggcca aggtgttatg tctatgggac aattacttac ttatgcagga atgctagaag
     9121 gaaaagaagt ttcttggtta ccatcttatg gaccagaaat gcgtggaggt acagcaaact
     9181 gtgcagtaac tgtatctaat gagccagttg gttctccact tataacagat gatgcaactg
     9241 cagctatatt attaaatata ccagcatttg aaaaattcaa agatgatgtt attcctggtg
     9301 gaaaaataat agtaaatagt tctttaataa aagaaaaagt tgatagaaca gatgtagatg
     9361 tttattatat accagcaaat gaattagcag ctgaattagg aaatgataaa gttgctaaca
     9421 tgataatgtt aggcgcttac ttaaaagtat ctgatactgt agatatagaa tctgtactag
     9481 aagcattcaa aaaagttttc ggacctagaa aagaaaaatt cgttccatta aacagagaag
     9541 ctttacaaaa aggtatggat gctacatgtt ctaaagcaac taactaataa agaaaaagat
     9601 gtcaaaaaaa agacaataga attatttcta ttgtcttttt tgctgataag tattaaaata
     9661 tttttatgac tgaaattaag cctataatga tattttatga actataaaaa tataatacaa
     9721 attacaagct tttcaattat gaaaggagaa tctttagtga gaaagtattt tggaacagat
     9781 ggagttagag gagtagcaaa tacagaacta acatgtgatt tagcatataa acttggtaga
     9841 gctggtggat ttgtcttagc tcaaggagac cacagagtaa aagtagtagt aggtaaggat
     9901 actagaatat caggtgatat gttggaagca tctttaatag caggacttat gtctgttgga
     9961 tgtgatgtta ttactgttgg aataatacca acacctgcag tggcatattt aactagaaaa
    10021 tatggtgctg attgtggtgt ggttatatct gcatctcaca atcctgttga atataatgga
    10081 atcaaattct ttaataagaa tggatataaa ttagatgatg aaattgaatt gaaaatagaa
    10141 gaatatatag acgatataga caaaattgat tgtcttccaa ttggtgaaaa tgtaggaaga
    10201 aaattacatg aacattgtgc acaaagagac tatgtagact acctaaaatc aataataagc
    10261 actgacttta agggattaaa agtagttttg gactgtgcta atggtgcgtc atataaagtg
    10321 gcaccaatag tgtttgatga actaggagca agtgtaattt caataaatag ttcaccagat
    10381 ggaaataata taaactataa atgtggctct acacatccag aacaacttca aagggctgtt
    10441 ttggaacata atgctgactt aggtcttgca tatgatggag atgctgatag attaattgca
    10501 gtaaatgaaa agggtcaaat tgttgatgga gaccatataa tgatattgag tgccttaaat
    10561 ttaaagaaaa ataataaatt ggcacaagat actttggtag ttacagttat gagtaatata
    10621 gggttgacaa tagctgctaa ggaaaatgga ataaatttat ctactacagc agttggagac
    10681 agatatgttt tagaagatat ggttaaaaat ggatataatc ttggtggaga gcaatctgga
    10741 catatgatat ttttagatta caacactact ggagatggag tgcttagttc tctaatactt
    10801 gcaaatataa tcttgcaaga aaagaaacct ttatcagaaa ttgcatcaat aatgagccaa
    10861 tacccacaag tattagtaaa tgcaacaata aaaaatgaaa ataagaacaa atatatggaa
    10921 tatccagaaa taaaaactga gatagaaaga atagaatcta ttttagacgg aaatggtaga
    10981 gttttgataa gaccatcagg aactgagcca ttagttagag ttatgttaga gggtaaagag
    11041 gaaggtcaaa taaaagaatt agcaacaaac ttagctaatc ttatacaaga aaaattatcg
    11101 taatttaaag ggtattctca gatataaata ctgaggacac ctttctaagc gccagaactt
    11161 agttatagac ataattattg agtaatatag gaactaagtt gacgaggtca gagttaatcg
    11221 aattgtcggc ggatgctctg cggtgtgttt accatcgaaa gacttcttta aataatagga
    11281 gcaatcctat ggacaaaggg aagccaaagt aaacttatat gacctaactc ttaaaatata
    11341 taaataatat ttttaggagg acacaaataa tgtgtggaat agttggatat ttaggaagta
    11401 gaaaggcagc agaagttata gtagaagggc tttctaagct agagtacaga ggttatgact
    11461 cagcaggagt agcagttaat agttctaatg aaaaagaact taatattaga aagtttaaag
    11521 gtagactttc tgtacttgca gaagacttag aaaagaatcc tattgatgga aatttaggta
    11581 tagggcatac gagatgggca actcatggag aaccatctga tgtaaactca catcctcatt
    11641 ttaatcaagc caaaacaata gcagttgttc ataatgggat aatagaaaac tatatggaaa
    11701 taaaagaaga attaatttct gaaggtgtta agtttgaatc tcaaacagat acagaggtaa
    11761 tagcacattt agtagataaa tactatgagg gtaatttatt agatgctgta tacaaaacta
    11821 tatcaaaatt aagaggagct tatgcattag gtgttatatg taaagaacat ggaaatgaat
    11881 tagttgcagt aagaaaagat agtcctcttg tagttggtgt tggtgaaggt gaaaacttta
    11941 tagcatcaga tatacctgca ttattaaaat atactagaga tgtttatttc ttagaaaatg
    12001 gagaagtagt tcatctaaaa gacgaaaatg taaccgttta tgactctaat agaaatcttg
    12061 ttgaaaaaga agtatttcat gtaacttggg atgtagaagc tgcgtctaaa ggtggatatg
    12121 actactttat gtcaaaagaa attcatgagc aaccaacagg agtaagagaa actttagaaa
    12181 gaagacttga tgataatgga aatataattc tagacagtat aaatatttct aaagaagact
    12241 tagaaaaaat aaataaagtt tatatagtgg cttgtggaac agcatataat gctggattac
    12301 ttggtaagta tgccatagaa aaatttgtaa atataccagt aataactgat atagcatcag
    12361 aatttagata tagcgaccca tttgtagatg aaaattcatt agtaatatta gttagtcaat
    12421 ctggtgagac agcagatact ctagcagtat taagagattc aaaggctaaa ggagcaagaa
    12481 tactttcaat aactaacgtt gtaggttcat ctatagcaag agaatcagat gatgtattct
    12541 atacttgggc aggacctgaa gtagcagttg catcaactaa ggcatatact actcaaataa
    12601 cttctttata catgatagct ttagactttg ctatcaaaaa aggaacaata actagagaat
    12661 tttatgatag tatgatttct aagatgaaag aaataccatc aaaaatacaa gaaatactag
    12721 acaatgaaga atatataaaa gaagttgcta aaacagttgt tagttctgaa catgcattct
    12781 atttaggaag aggtatagac tatagcttag caatggaagg ttcattgaaa ttaaaagaga
    12841 tttcatatat acatgcagaa gcttttgcag caggagagct aaagcatgga acaatagctt
    12901 taatagaaaa aggaactcct gtaattgcca tagctactca agaaaagtta tttgaaaaaa
    12961 tggtttctaa tatggaagaa gtaagagcaa gaggagctta tgtagtagca atagctcaaa
    13021 gccataataa ggatgttgag aaagctgctg ataaaataat ctatatacaa aattcagatg
    13081 atattttatc accaatatta gcagttgtac caatgcaatt acttgcttat catgtctctg
    13141 tactaagagg atgcgatgta gataagccaa gaaatctagc taaatcagta acagttgaat
    13201 aaaaacagat taaaaattaa atagataata tttattgaaa agaactcatc ctgttatttg
    13261 tattttatag gatgagtttt ttagataaat attaaatttg ttttgttttt gctataataa
    13321 attttataaa aagattgata ttaaatcatc tgtaaaatga taaatatata gaccatacca
    13381 ggtataggga acgataaata tagttcatat aaaatatagt gagtacttaa taaacatata
    13441 gtcaatatca gataaaaaaa ataatagctt atgagaaaaa ttaaaataca aggtattagt
    13501 aaccttgtga taagataaag tgagtagttt aaaataagaa tataaggaac tatttataaa
    13561 agaatataat gaagctaata gagtataaga aaattacttt attttagtaa aataatttca
    13621 aataaaaatt tttttaaatt gggagtataa attatgacaa atgattttaa aaaagaaaag
    13681 aaagaagatt attttgttaa tcttaaggca atatctactg aagttttaca agaaaaagtg
    13741 caagataacg cttgggttat agttgatact cgcttaaatg atgcttataa tggctggaag
    13801 ttagatggag taaaaagagg tggacatata aaaggagcag tagatttttc tgctaattgg
    13861 ttaagtgtat acttagatag aaaagatgaa gtgttagaac aagcattgaa aactaaaaga
    13921 attgatttag ataaaaatat agtattgtat gatgcaaatg gaaaagatgc tttggttgta
    13981 gcagattatt tatctaaaaa aggatataaa tatctatata aatatgatat taaacaatgg
    14041 gcagacgacg aaaatcttcc aatggaaaga tataaaaatt atcaaatgat agttcctgct
    14101 tttataataa aagatatatt agatggaaaa attcctgaga catttgaaga ttcaaagaat
    14161 ataaaaatga ttgaagcgag ttggggagaa gaatcgtata caaaagggca tatacctaca
    14221 agtgttcatg taaatactga tattatagaa cctcctccaa catggatgct tgataatgat
    14281 gataacttaa ctaagtttgc tttagactat ggattaacaa aggatgatac tgtaatagtt
    14341 tcaagtagta cacctatggc atcttataga ctagctgtta tattgagata tataggagta
    14401 aaagatgtaa gagttttgaa tggtggaaca aactcatggt tatcagcagg atatgaatta
    14461 gaatttatta gtaatccaaa acattcatgt actaattttg gagcagatat accagttaac
    14521 tcacaattag ttgttactac atctgaatta agacaaaaac taaaagaaaa aaataagttt
    14581 atactagtag ataaccgtac ttgggatgaa catataggaa aagtatctgg atatacatat
    14641 tatgataaaa aagggcgtat accaggagct ttatatggac attcaggtag tgatagtgtt
    14701 tcactagaag aatatcgtaa tattgataat acaatgagaa ataaatatga gattttagaa
    14761 atgtgggaca aggaaaatat agatgtgaat aaacagctta tatttatgtg tggaagtgga
    14821 tggcgtgctg ctgaagtatt aacatatgca aatgtcatag gagtggaaaa tacctccctt
    14881 tatagtgatg gatggatggg ctggagtctt gataattcaa atttaattga agtgggagaa
    14941 cacaaataaa gtttttgaaa gtacaataga gttgtttaaa acaaaggtgt ttttgattta
    15001 ttaggaagag tgtgtaaatt gtgtattggg aagtggactt aggtatgttc atttggagct
    15061 atggaaactg ataaaaaagt attatctgtt tattttgctg gtaaaatatg aatagattat
    15121 agattataga ttatagatta tagattatag attatagatt atagattata gatttaagta
    15181 tagactaagt aatttatatt acagaagaga atatataaga attaatgcaa gatgtatttg
    15241 atacatataa gaaattggca agtccaggag aaggatagag aaaattgaga ttgaagagtt
    15301 taaaagagat tattagatga aaaatacaaa aatgtataaa aatacatatt gagaaagtat
    15361 atctctctta aatttgttaa taattctatt atacagaaaa acatatttaa gggggatttt
    15421 ttactatgaa aaaagtaaaa ttagctataa gcttttttat attaatgatt ataggaatga
    15481 caatatctta tgcagataca agtataaata ctagatacaa tagattaagt aaagctcttg
    15541 aaatatcaga agcaaatttt aaattttata atgttaaaat taattctgtt ataaatcata
    15601 atttatcaaa taaagaattt cataatattt ttatagaaat aattaacaat ctaaagttgg
    15661 ataaaaaagg aataaattgg aatcaaaaag ggtctggcga taaaatacaa ttatgtgcta
    15721 ctataaaagg tagcgataaa gaaatttcta taaaaggaat aaataaaaat aacaaagaaa
    15781 gttacatagt agttgacata ttggataaca aagtatataa acataaagag gttatttata
    15841 gtaacgtaga aaatgtgtta aataaatatt catctcaagt agatgtgtct gcttgtattg
    15901 ttggagaata cacaaaaagg ttacaaaaca acaaatatga tgatatttta caaaaaatat
    15961 tatataatat gagtgctaag caaatagatg aagttaaaga cgtaaacttt ttatctataa
    16021 cagcatatag taaagtatta aatgattatg aattagaata tttaggggaa aaaattaatt
    16081 taaatatagg aattaaatat aatgaggatg acggaaaaac actcatatat attgccacac
    16141 caattataaa attagattat taattatgag gagatcaaaa aatatggcta agataatagt
    16201 aaaaaagagt aatccactta aaggtagtgt taaaatagat ggtgcaaaaa atgcagtttt
    16261 accaataata gcagcgactt tattagcaaa cggaaaatca acattaaatg gagtaccaaa
    16321 tttaagagat gttcatgtta tatcagattt attaagacat gtaggagcag aagttgaata
    16381 taaagaaaat acacttactg ttgatgcaag caatataaaa acttgtgaag ctccatatga
    16441 gcttgtaaga aagatgagag cttctttttt ggttatggga ccattgcttg ctagatttaa
    16501 tagtacgaaa atttctatgc caggaggatg tgctatagga acaagaccta tagatttaca
    16561 cttaaaagga tttaaagctt taggtgcaaa gatagaaatg gaccatggtt ttgttgaagc
    16621 agcaacagaa aagttagtag gaaataaatt atatttagat ttcccatctg ttggagcaac
    16681 tgaaaacata atgatggcag cttctttagc agaagggact acaataatag agaatgcagc
    16741 agaagagcca gaaatagtag atttagcaaa cttcttgaac gaaatgggag cagatgttaa
    16801 aggtgcaggt actaatacta taaaaataaa aggtgttaaa gagttaaaag gagcagaaca
    16861 taatgtaatt ccagacagaa tagaagcagc aacttatatg gttgcggcag ctatgacaaa
    16921 aggtgatata actgttgaaa atgttttaat ggagcattta aaaccagttg tagctaaatt
    16981 aagagaagct ggttgtgaaa taacagaaat ggacaattct gtaagagttg taggtccaaa
    17041 agtattaaaa ccaatagata taaaaacttt accacatcca ggatttccta cagatgttca
    17101 agcacaattt atggctatgc ttactgtagc caatggaact ggtgtagtta tagaaactgt
    17161 ttttgaaaac agatttatgc atgttgctga atttaataga atgggtgcta atataaaaat
    17221 agatggaaga agtgcggttg ttaatggtgt agatgagcta cacggtgcag cagtaaacgc
    17281 tactgattta agagcggggg cagcccttat tttatgcggt cttatagcag aaggagaaac
    17341 tcaaatagga gaaatatacc atatccaaag aggttatgtt gatatagata agaagataac
    17401 agctctaggt ggtcaaatcg aaatagtaga agattaataa ttggtttata gaagaaagtt
    17461 ataaattaat agggttgttc atatacttaa atacaaggtt ttaaaagcta aggaggagag
    17521 tatatgaaga acccattggt tgttttgtta ggatttgtga cttgctctgt gttagttcca
    17581 tcacttataa ctttagtttc ttataaaaat gtagaattaa ctgaaaaagc agagagccca
    17641 gtatctataa acaaaactat taaaaaaagt gatattgaag acaaaggtaa taaagaagaa
    17701 aaaaatacag tgaactatga aactgtaaat aaaaaagcac caattatcaa tgtatataat
    17761 catataacag ggaaaaccga aaagatggac atggagaact atttatgtgg agtactagct
    17821 ggtgagatgt cttcagagtt tgatatagaa gctttaaaag ctcaatctgt agcagctaga
    17881 acatatgtag tatataaaca ggaacatggt aaatctagta aacataaaaa tgcagtagta
    17941 tgtactgatt ataaacattg tcaagaatat aagagttatg atactcttaa aaaattaaat
    18001 ggtgaagaat ggattaagaa taaatattcc aaaatccaag aagcagttag aggaactaaa
    18061 ggtcaaataa taacttataa tgataaggcg atacttcctc tttatttttc tacatcttca
    18121 ggaaaaacag aaaatagtga agaagtattt tctgcaaaat atccttattt aaagtctgtg
    18181 gaaagtcctt atgataagta ttcccctaaa tttgcgtcaa cacttaaaat aagtaacaca
    18241 gattttgtta aaagtcttag aagggcatat agcactattg tgatagatgt gaataattta
    18301 agtaaacaag tttcaataac taaaagaagt gatgccggaa ctgtagaaaa aataaaatta
    18361 ggaaataaag aattgactgg aaaagacatt agaactgttt ttaaattgaa ctctgcaaac
    18421 tttgacataa aatttggaga aggatacata gatttcgtgg taaaaggata tggtcatggt
    18481 gttggtatga gccagtgggg agcagaagga atggcagaag agggctataa atattatgat
    18541 atattatcac attactacac agatacaaaa ataaaagata tatactaata attgtataaa
    18601 atgccaaaaa cacgtcaata atccaaatgt agaaatatat ttggaggtgc aaaatgaaga
    18661 aaaagctgtt agaaaaagat ggtttttatt tatctttgtt tgtatgtgtt tgtttattag
    18721 cagtaggtgg agtttggttt acaaataata atgtagataa attggcttct aataaaggaa
    18781 ttatggaaaa tgctaataaa gatagtgaag aggaaataca tttaattgaa aaagacaaga
    18841 aagatgctat ccctactgca acggattcaa aacaaaactt agaaaaagct aagtcaaaag
    18901 aggaaaataa atcgagtaca acaaaattaa attacattgg agataaagta ataagaggat
    18961 attcagaaaa agagcctagt tattctaaaa cacttgatgt ttgggaaact cataaaggtg
    19021 tagatattag ttgtactaaa ggcaaagaag taaaatctct attaaacgga atagtagtag
    19081 atgtatttga tgatgaagaa tatggacaat cagtcaaaat aaaaagtgac aataacattg
    19141 tagtagtata ttcaaatcta gataaaaatg ttagtgttaa gaaagaacag aaggtaacag
    19201 aaggacaatc tctaggtact gtaggtagta cttctcaaat agaaagtgaa gaaggtatac
    19261 atgtgcattt agaggcgtat agtggagaaa aatctataga cccaatgagt ctaattaagt
    19321 aatagtataa caagtttaat catatttggt taagcttgtt atattttttg gtgtttttac
    19381 atatatatca ttaaagctat tatgtgaggg gggtaatctt tgagatctca tatagaggaa
    19441 agggccatag tggtagcaaa atatatactt gaaaaaaaca ctacagtaag acaaaccgcc
    19501 aagacatttg gagtaagtaa aagtacaatt cataaggatg ttacagaaag attgaaggaa
    19561 ataaatccat cccttgccaa agaagttaaa aatgtgctgg acaaaaataa atcagagaga
    19621 catattagag ggggattagc aacgaaatta aaatatgaga aggaacataa aaaaatgtag
    19681 gttaaaaacc tacttttttt attgaattaa attataaaaa gaaatatatt aagtaattat
    19741 aaatagcaaa ataataatac tctcaaaaga tttattttct cttgattaaa gcgagatttt
    19801 tgtatatgct ttattatagg agtattaaaa taggcttata atataatcta atattataaa
    19861 taaaggagtt gaaaaaatgg ctggagctga tataggcata gatttaggta ctgcaaatgt
    19921 gcttgtttat gttagtggta agggaatcgt tttagaagaa ccatctgttg tggcgataga
    19981 caaaagaaca gattctgttt tagctgtggg agaagaagct aaaaagatga tagggagaac
    20041 accaggtaat atagtcgcta taagaccttt aagagatggt gtaatttcag attatgatgt
    20101 aactgagaag atgttaaaat cttttataga taagatagtt gataaaaagg gatttggaag
    20161 attttttatg ccaagaatta tggtatgtgt accaacaggt gtcacagaag tggaaaaaag
    20221 agcagtagaa gatgctacga gacaagctgg agctagagaa gtatatatca tagaagaacc
    20281 aatagcagct gccataggag ctggtgtaga catatcacag cctaatggta atatgattat
    20341 agatattggt ggaggtactg tagatatagc tgtaatatct ctaggaggag ctgttgtaag
    20401 tgaatctata aaggttggtg gagatagatt tgatgatgct atagttaaat atatgaaaaa
    20461 acaacacaat cttcttatag gagaaagaac agcagagaaa atcaagtttg aaataggttc
    20521 tgcatttaag agagaagaag aaaaatatat gaagataaca ggaagaaatt taattacagg
    20581 acttcctagt tctataacta taaattcaac agaaatgttg gaagcactta gagaatgtgt
    20641 tgagcaaata gtagttgcta ctcatgctgt tttggaaaaa acgcctcctg agttagcagc
    20701 agatatagga gatgtcggta taataatgac tggaggaggt tcattattat atggattaga
    20761 taaaataata gaacagagga caggaataac tgttacaata gcagatgaac cattatcttg
    20821 tgttgcaaaa ggtacaggaa tagctttagg ttcaatagac ttacttgaaa ctggtgggtc
    20881 tttcaaaaga aaataattag gagagtttag aatgttaaat atagatgaaa taaaaaaatt
    20941 aataccacat agatatccat ttttattagt agacaagatt acagagttag aagttgggaa
    21001 aagagctgtt ggtataaaga atgtaacagt taatgagcca tttttccaag gtcactttcc
    21061 agaatatcct ttgatgccag gagtactaat agtagaagct ctagcacaag tatgtggagt
    21121 ggcaatgatg tctgtagagg aaaacaaagg aaaactaggt gtatttgcag gtatagataa
    21181 agttagaatc aagagagaag taagaccagg agatacatta actatggaag ttgaaatgac
    21241 aactcttaga aaaaatatag ctaaggcaga tgctaaggca tatgtaggtg aagaacttgt
    21301 ctgtaaaggt gaattaatgt ttgctttagt agaaaaataa aaacttgaaa tataaaagta
    21361 aaaaggtaga taatttggag tatttaatca gatactctaa aatatctacc tttttatata
    21421 aagaatttta tcatttagtt tatatttaga ttaggtggat actaataaag ccaaggctat
    21481 tgtttcagct aaatctaata taaagctaag gcgtatatta ttaaatgaaa gtttattatt
    21541 ttcatcaatt ttatctacaa ttcctactat agaataattt cctatttgag gtagtttttt
    21601 gccaacacct tttccgggca ggataggtcc ttctctaatc tgtatattac ctatgttact
    21661 ctgcgacccc aagcaagcat ctatagccaa gaagttacct tgtatatgtg tattttttat
    21721 agtatctaaa gactcatata tatttaaggc gtgaataggg ttatctagtg taccgtaaac
    21781 ggggtattta aagttactgt tcttaagtat tgttccaact aaagggccta aagtatcacc
    21841 tatagccctg tctgttccta tgcaaacaac aatcgtattt tcattaatta tagtttttag
    21901 aactgaactt agcatctgta taacatcatc atcgctgtag tttactttag ctaaatacaa
    21961 taggaacacc cccttcaaaa aaatatatga ataaaaagca ttaaaaagac ctaactttaa
    22021 atttcagata gatagaaaat tttatttgtc ttacaaaaaa aggaatagaa aaaatatgac
    22081 taaaaatatt gacaaaattt taaaaaaata gtaagctagt aaagtaaaac aaaacttaaa
    22141 tcttgattac cttatcaaga gaggctgagg gataggccct gtgaagccca gcaaccaccc
    22201 aaatgggaaa aggtgctaat tcctacaaga caaaagtctt gaaagatgag gtcagttaat
    22261 tagtatgtaa ttacgattat taacctcttc ttataaagga gaggtttttt attttgagta
    22321 aatttctaaa attaaaaata aggtaaaacc tataataaaa attaagaata aataaggggg
    22381 aataaaaatg gcaagacatt tatttacgtc agaatcagtt acagaaggac atcctgataa
    22441 gatatgtgac caaatatcag attcaatatt agatgcatta ttagaaaaag acccacaatc
    22501 tagagtagct tgtgaaacta cagttactac tggtttagtt ttagtagcag gagaaataag
    22561 tacatctgct tatgtagaca ttcctaaatt agtaagagaa acagtaagag aaattggata
    22621 tacaagagca aaatatggat ttgattgtga tacttgcgca gttataactt ctattgatga
    22681 acaatctgga gatatagcta tgggagttga tgaaggtcta gaaagtaaga ctggagaaga
    22741 gatagaagaa gaaatagaaa aagttggagc tggagaccaa ggtataatgt ttggatttgc
    22801 atgtaatgag actccagaat taatgccact tccgatatct ttggcacata aattatcaag
    22861 aagacttaca gaagttagaa aaacaggttt agttgattat ttaagaccag atggaaaaac
    22921 tcaagttact gttgaatatg aaggaagtaa agctgtaaga gtacatacag ttcttatatc
    22981 agctcaacat tgtgaaacag tatcaaatga taaaataaga gaagatttaa ttaatcatgt
    23041 tattaaggaa gttataccag cagaattact tgatgaagag actaaaattt atataaatcc
    23101 aacaggaaga ttcgttatag gaggaccaca aggagataca ggtcttacag gaagaaaaat
    23161 aataatagat acttatggtg gatattctag acatggtgga ggagctttct caggaaaaga
    23221 ccctacaaaa gttgatagat ctgctgctta tgcagctaga tatgttgcaa aaaatattgt
    23281 tgcggctggt cttgcagaca aatgtgagat agaacttgca tatgctatag gtatagctag
    23341 accattatct atatttatag atacttttgg gacaggcaag gtttcagaag aaaaacttgt
    23401 tgaattagta aataaacact ttgatttaag accgggagcg ataataagag acttagattt
    23461 aagaaagcct ctttataaaa aggttgctgc ttatggtcac tttggtagaa ctgatataga
    23521 tttaccttgg gaaagaactg acaaggttga gcagttaaga aaagatgctt taggtgaata
    23581 atttttaact aaaaagctgt tagaatgtaa ttttacgatt actttctaac agctttttta
    23641 ttatgagtta aatattttta ataaatgtta atttatcatc atataatgaa taaacagtat
    23701 ttaatctggt caatacattt tatataatac tctactaaat ttatacatat tatgggatat
    23761 atgttaaagg atggttaaga atgtgttaac taatgttaaa taattaaaaa tatattgaaa
    23821 tatcacaata atgagtctaa tataatctta ataaacttac actttaaaaa taattttaat
    23881 tgggggggag tagtgtatgt caggcaaagt aaatattaaa acggttataa gttttgctgg
    23941 agcttatgtt gctactgtaa taggttctgg atttgcaact ggtcaagaaa tactgcaatt
    24001 ttttacgttt tatggatatg cgggtattat aggtggaata atctctatgg tactattttc
    24061 atggtttgga gcagaagtta tagataaggg aagagaattg aaacttaagg agccaataaa
    24121 aatttatcaa gtatattgtg gaaaatatct tggaacattt tttgaatggt ttggtccatt
    24181 gtttttattt ggaacattag taataatgat tgcaggagca ggagctacat tatcagagta
    24241 ctatggatta aatccatatg taggtaggat tggtatggca atcgtttccc taataactgt
    24301 ttcattaggt ttgacaaggc tttctaaaat actaggtaat ataggaccta taataataat
    24361 atttacactt ttagtaggag caattagttt atttagcaat attgatgctt tatcaaatgc
    24421 tggaaatatg gttgatagtt taaatattaa aactgctaca tcaaatggat atttctcggg
    24481 agtactttat acttgttaca atgtaataat agtaataaca ttcttgacag gaatgggagc
    24541 ttctgcagta aataagaaag atgctgtatg gggtggtata gtaggtggag tagcacttat
    24601 ggcagcagct ataatgatga atttggcatt actttcagac ataggaaata tatacacaaa
    24661 agagatacca gcactttact tagctgataa gatatctcca ataataggta ttttattctc
    24721 agtagtactt ttactaggaa tatacactac agctgtacca ttgttatggt cagtaacaaa
    24781 ccgatttgta gaagatgacc accctaagtt taaaattata acaatagtgg taagtatatt
    24841 agcttgtata ggaggtttac tgccatttga taagttagta ggtacactat atccatatac
    24901 aggttacatg ggaattttaa ttttactatg tatgctttat agaagaatta ctaaaactga
    24961 ggggtacaag gagaataaat ctgaaataag ttagtactgt aatatactta tggaatttaa
    25021 tttatactct aaatatagag caattaaaat aaaatagcta tttaaatatg gtacctgtat
    25081 ttcatggtac catattttat ggatgcagat tttttttgtt tctgataaaa tgtataatag
    25141 ttggaaatta cgttaagtat aaaaatataa aacttttcta cgattatcat agttttaata
    25201 tataaaatta tactaacatt taaatggagc gattattagt atttttagga gataaaaatg
    25261 gaaaaattag aaggaatgat aagtgaaata gtctttaaaa acgaagataa tggttataca
    25321 atagctcacc tggtaaatga aaatgatgaa attgtggttg taggatgtat gcctactttg
    25381 gcaattggag aaagcataga agttgaagga aagtgggtaa atcataagat ttatgggact
    25441 caatttgaag tgaatagttt tatgccagta acaccatcat ccttagaagg aatttatgtt
    25501 tacttatctt ctggaatgat acatggtatt ggtgaaaaaa tggcaaaaag aataattgat
    25561 aagtttggtg tagatacgtt agaggtgata caaaattcac cagaaaaact acaagaagta
    25621 gaaggtatag ggagtaaaaa agtaaaacaa atagtaaaaa gttatgaaga agacagagaa
    25681 ttgagaaata taataataca gctatctcct tttggaataa caccaaatta ctgcctaaaa
    25741 atatataaaa aatataaaag cagtgcaata gaagttataa ataaaaaccc ataccaactt
    25801 gctgaagata taagaggaat tggatttaaa gtagctgata gtatagcaag taaaattggt
    25861 atagataaaa actctaaaga tagaatttgt cagggaatct tatacacttt aaataaatct
    25921 ttaagtaatg ggcatacata tttaccagag catgttctaa tacaagattc ggaaaaatta
    25981 ttggagctaa atggagaaat aataaaagag tgtgtaatga tgctagttta taatcaaaaa
    26041 atacatatag agaaagtaaa caatgaaaat cttatatacc ttatgccata ctatttagct
    26101 gaaaatggag tatgtagtca aatagtaaaa ttatcacagt atgaatttga agacttaaaa
    26161 atagatatag ataacgagat taatgtttta gaagaagata agaaaattaa gttagcagaa
    26221 aaacaaattt tagcagtcaa agaatctgtt aatagtggag tattaattat aactggtgga
    26281 ccaggaactg gtaaaacaac taccattaat gctatcatag atatatttga aaataatggt
    26341 aaaagtgtga ctctggcagc tccaacggga agagcagcaa agagaatgag tgaaacttct
    26401 aataaagaag caaaaactat acataggttg ctagaaatgg gattttcaac agatgatgat
    26461 ttaacttttt ttaaggatga agaagaccca ataaattcag atgtaataat tgttgatgag
    26521 gtatcaatgg tagacattat cttaatgtac aatttactta gagctataaa gttaggaaca
    26581 agagtaattt tagttggaga tagtgaccaa ttaccttctg taggtgctgg aaatgtactt
    26641 aaggatatga ttaattctaa tattataaat gtagttaaat taaatgaaat atttagacaa
    26701 gcgcaagaaa gtatgataat tgtaaatgcc cataagataa acaatggaga accactttat
    26761 ctaaatacaa aaggtaaaga tttctttttt ataagaaaat caactaatga agaaatttta
    26821 aatgaaataa taggattggt taatgaaaga ttacctaaat tttataaagt tgataaatta
    26881 aaagatatac aagttttatc ttcaatgaga aaaggtgaat tgggagttac taatctcaat
    26941 atagagttac agaagtatct taacaaaaaa gaaaaattta aagttgaaga aagtttttct
    27001 aaaagattat ttagagttgg cgataaggta atgcaagtaa aaaataatta tacaaaaaaa
    27061 tgggaaacag aagaccaaaa agaaagtgga gaaggtatct ataatggaga tataggatat
    27121 gtttatcaca tagataaaga taagaaaact atttatatat tatttgacca gactaaaatt
    27181 gtatcatacc tatatgatga attagatgaa attgaccata gtttttgtac aacaatacat
    27241 aaaagccagg gaagtgaatt tccagttgta gtattgccaa tagcgtgggc tcctcctatg
    27301 ttacttagcc gtaatttatt atatacagca gtaacaagag caaaaaaatt agttgtatta
    27361 gttggagatg tgaaatatct tgaatatatg ataaaaaata atagagttaa tcaaaggtat
    27421 tcaaatttag gatataagct aaataaattt aaacaagaag ggttgttgat agaataaata
    27481 tgaaaatatg caatgataat tttattaaga attttaaaaa tatgattaat aaatgtttgg
    27541 attttatata tcctgagaat ataagttgca taatttgtga taaatccata aagaaaacaa
    27601 atacttattc aatatgtaaa agttgtttta aagaaatgaa ttttatacaa gatggttgca
    27661 tgaagtgtgg aaaaccaata atacgtcatt caattgaaaa agaatttatt gaagagtgta
    27721 gttattgttt taataaagac ttttattttg ataaatcaat atcttgtatt gaatacaatg
    27781 atgtgacaaa aaagatggtg ttagggctga agtataacca aaaaaccttt atggctaagt
    27841 atatagctca aataatgaaa gaaaaattat atttagaaaa cataaaattt gattatatat
    27901 tatttgttcc acttcataaa aaaaggctaa ataaaagagg ttttaatcag gcacaaaaaa
    27961 tagcatttaa tttaagtaaa atagtaaata ttccattatt agattgcata agtagaaaaa
    28021 aatatacaag aatgctatat aaattgaata agaaagaacg aaaagaagaa ttaaaaaatg
    28081 tatttgttgt taaagaaaat gttaaattaa taaataataa aaatatactt ttaatagatg
    28141 atatatttac tactggtcta acaacaaacg aaatttctaa acttttaaag ttatcaggtg
    28201 ctaataaggt ttttgtattg actctactta caaaagcaaa tgataattat attatggaat
    28261 aatcttatat attgacaatt ttagtttaaa atattaaaat gaataagtga tatttaggtc
    28321 tgtggttgaa agtccaagcc agtcgcaggc aaagggatcc acgtaagtta acactaaaaa
    28381 ttgggttaat gatcatggtg cggcttagaa gtaagaccta ccgataataa aatcgagaga
    28441 gagtagtagt gcggcgaacc caagcgaacc ctccagtagg cgagtgtggg gtcaaaaacc
    28501 aggtcagcta aatatcatat taaaagagag ctagcatacc tttatgtata gctctttttt
    28561 atatataata aatttaggtt gagtcataaa gaggtgatat gtttgaataa aagacaagaa
    28621 aatttattaa caacattgct attaaaagaa gagtttataa atgttaataa gattgccaat
    28681 gattttgagt gttcagaaag gacaataaga aatgattgca aatatattga tgaatggtta
    28741 tctacttttt gtaatgctta tatcaaaaga aaacctaata ttgggattaa atttagtgga
    28801 gatggaacag acaaaatact ggtaaatcag aagttgcgag gtgaagttaa aagagtaaat
    28861 agtgagcttc ataagcaagt tgagatatta aatttactac tttgtaataa taaaaaagtt
    28921 actttaaatg atttatctaa taagttgtac ataaataaaa atattgtcag agaagaaata
    28981 agtaaattat cagtagcatt aaataattat aatttaaata tctcgactaa aaaaggcagt
    29041 ggtatatata ttgaagggga tgagaaagac ataagaataa tgttagtatc attcttattt
    29101 aaatatatag ataaatacag attaaacata gatgaaatag agtacttcca tatagtagat
    29161 ataataattg taaaaaacat aatgcttact atagaggagg atatggatat aagacttaca
    29221 gatatatcat tcaagcaatt gatgctattt ttgcttataa atataatacg aataagactg
    29281 ggaaattctt taaaagtatc aaatactaag aaagagctta agctaaaaat gcttatattg
    29341 gatatagaag atgaattgaa atctaattta tccatagtat taaattatga agaaaaattg
    29401 tttatagaat ctttaatatt gggtatgaac aaacaaataa atagtaataa tattaagaaa
    29461 tctttatatc taaatgaaga attagcaagt tatacaaaaa aaattataaa tttagtatca
    29521 gaagaatcag gaataaattt taataatgat atattacttt atgaacaatt aatatgtcat
    29581 ttgaatgtta caatgcatca aatgaaaagc aatgtttact tagaaaatcc acttttagat
    29641 aacataaaaa ctaaattttg ttttttattt acagtaatat caagttcaat agaaattgaa
    29701 ttaaaaggaa aacaaataac ggaagatgaa attggttatc ttacacttca ctttcaaacc
    29761 tctctagaaa gaaaatacag caaaagggaa tcaaataaaa aggcaagtat tgtatgtcca
    29821 tttagttttg gagtaagtat gctattaaaa gtaaagatag aaaagagatt tgataacata
    29881 aaaattattg aaacattaag agaggaagat ttaaaaagag ataactttaa taagactata
    29941 gattttataa ttgcatttca agagtatgaa aatatccaaa aaccaatttt tataacaaca
    30001 ccattattta ctgatgagga tgagaataaa cttaaagagt tcacaaacaa aataaaagaa
    30061 aaagacactt catataaact tatgaacaga ttaatgatgt ctgattattt aataagagag
    30121 ttagaacatg atgatattta tgaagctata acatatttaa ctaatttatt aattgaaaaa
    30181 cattatgcag aaaaagagta tttacaatct attataacaa gagaaaagtc atatccaacc
    30241 aatgttggaa aaggaatatt attccctcat ggagacatga aatatataaa acaatctgtt
    30301 ttatgttttg caaggttaaa aacaccaata aaaattagaa atggaaagga tataaagatt
    30361 atacttttgt tagcatataa aaaagatgat gatagaaaag tatttagaga attatttaaa
    30421 gaaatatcta atttaacaga ggatgaaaat atgctagata ttctaagtaa atgtgacatt
    30481 gaaaaggtaa aagatattct tatataaaat tcatagtgaa ctatggataa gcacaaaatt
    30541 ttccatgtga tggaaaaagt tgtgcatgtt tttttgtttt tataagatat tatatgtttg
    30601 taaggtataa ataatctaaa agtagagaag taacttagga ggaaaaaatg gaagaaatag
    30661 ttttaaagat tataattcat gctggaaatg caaaatctat gctttatgaa gcacttgact
    30721 atgcaaagga aaacgatttt aaaaaagcag atgaattaat tgaaaatgca aatgaagaaa
    30781 ttttaaaagc acataaagta caaactgaac ttatacaaaa ggaagctggg ggagataaat
    30841 cagatatatc tattttattg attcactctc aagaccattt aatgacttgt atgagtgaga
    30901 gaaaccttat aaaagaaatg attatgttaa gaaaagaaat tcaaaaatta aaataaaaaa
    30961 attaaggggg atttaaaaaa tgaaaagaaa agtatattta ttttgtagct ttggtatgtc
    31021 aacaagttta cttgcagata aaatgcagaa ggtagcagat gaacacaatt taccaataga
    31081 agtagaggca tttccgatag cagaaattga caaaatagtt gaagaaaaaa atccagattg
    31141 tatattatta ggaccacaag ttaaatacat gctaaaggag ttaaaaccaa agtttgaagc
    31201 tcaaggaaaa cttatagata taatcaatga agttgattat ggaactatga atggggaaaa
    31261 agtattaaaa cttgctataa agctaataaa atctaaacaa gcgtagaatt atagtaaaaa
    31321 ataataggaa atgagggtgg atagatgaat agattggaaa gaatacttat gccattggct
    31381 gaaaaaatag gtaaaaataa attattaatt gcaattagag atggtttttt agtatcatca
    31441 ccattattaa taataggttc attattttta ttagtagcaa attttcctat aaaaggatgg
    31501 aatgaatttg taggtcaaat ttttggtcca gattgggctg taaaattgca acaaccaact
    31561 gtagcaacat ttgaagtaat gactctactt gcagttttag ggattggata ttcttatgca
    31621 aagcaaatag atgtagaccc aatagcatca gcagcagttg caatagttgc cttttttata
    31681 ataacaccat ttgtaatacc atatacacca gaaggaacag aatcagttta catggtaaca
    31741 ggtataccac taggttggat gggttctaag ggaatgtttg taggtatgat aacagcaata
    31801 acctctgtaa aattatttgc tgcagttgta aaaaaaggat ggacattgaa aatgccagat
    31861 ggagttcctc caactgtatc aaaatcattt gcagcattaa taccaagtgc aatagttatg
    31921 gtagttttct ttttagttaa gatagctttt gaagctacac catatggaag tatacatgaa
    31981 tttatattta agtttttaca aatgccatta ttaaaattag gaaatagttt aggtgctatg
    32041 gcaatcgctt atatattctt acatttattc tggttctttg gaataaatgg aagtagtgtt
    32101 gttggggctg tgtataatcc aatattaaaa attctatcag ctgaaaactt agctgctttt
    32161 caagctggtt caaaaatacc aaacataata acaggtcaat tccaagatat gtttgcgaca
    32221 tttggtggag caggtagtac actatcatta gtcatagcta tgttattaat atgtaagagt
    32281 aaacgtataa agtcaatggg aaaactatca attttaccag gaatatttgg tataaatgag
    32341 ccattgatat ttggtctacc aataatgctt aacccaatac tattgatacc atttgcaata
    32401 gttccaacaa taaatataat aatagcttac ttctgtatgt cagcaggatt agtgcctctt
    32461 acaaatggag ttcagttacc gtggacaact ccaattatat tctctggttt tttaacaaca
    32521 ggatggcaag gtgcagtctt acaattagta cttcttatac taggaatatt tatgtatata
    32581 ccatttataa aaatactaga taagcaatac ttgagagaag aaaatgaaac tgttgaagag
    32641 gaagatgatg atatatcttt tgatgattta gtattatagg aggaagatta tgaagaaaat
    32701 agttatgata ttggaccaaa tacaagctgg agctggagga aaagagaaaa gtaatatacc
    32761 tcctgctgga aaatcaagcc cattaggacc aggtgtaatg atggagcaat ttttaaatga
    32821 atctaaggta atagctacct tattttgtgg ggatgaattt tttgtaaata atcaagaaga
    32881 agtaacgagt aagatgatag ctatggtaaa aaaattaaac cctgatgtag taatctgtgg
    32941 accaagcttt aattacgaaa acttttctaa gatgtcagca atactgtcta aaaatataaa
    33001 tgataaaaca gatataccag cttttgcagc tatgtcagaa gaaaatatag atgtgataaa
    33061 cgaatataaa aatgacatat gtatagttaa gactccaaaa aaaggtggaa ttggtcttaa
    33121 tgattcgtta aataacatat gtaaattggc aaaagcaata gcaaataaag aagatataac
    33181 tttgatgaaa gaagaatttt gttattaata agagtattaa ttattagcaa gtttaaatat
    33241 tatactattt ataataagca tacattagta aaatctatat aatttaagga ggggaatttt
    33301 aacatgtggg gaatgatagc gacatggaga atggccctag aaggaataac tgaggcatca
    33361 gaacatttag aaaaaggcat ggaagcaggt gatgctgtag agcttgctgt aagaagggtt
    33421 gaagactatc cattctataa atcggttgga tatggtggac ttccaaatga aaattgtgag
    33481 gtagaacttg acgctgcatt tatggatggt aacacattag atattggcgc agttgctggt
    33541 ataagagatt attctaatcc tgtcagcata gctaggaagt taagttatga gaaggtaaat
    33601 aattttttag ttggaatagg tgctgaagat tatgctcata aaaatggatt tgaaagaaaa
    33661 aatatgttga ctgatagagc gaagttacat tataaaaaga gaaaaaaaga gactttagac
    33721 aaaggattaa gcccatatgc tggtcatgat actgttggta tgatatcttt agacaaaact
    33781 ggaaaaatgt gtgtagctac atcaacaagt ggattgttta tgaagaaaag aggtagaata
    33841 ggagattctg cactatctgg ttcaggattc tatgttgata gtagtatagg aggagctaca
    33901 gctactggtt tgggagaaga tttaatgaag ggatgtatat cttatgagat agttagactt
    33961 atgaaagaag ggaagcatcc acaagaagca tgtgatattg cagtaaatga acttgataaa
    34021 cagcttatca aaagaagagg aaaagctggt gatttatcat tagttgccat gaataataaa
    34081 ggtgaatggg gagtagctac aaatatagct gattttactt tttcagtagt aactaaagaa
    34141 gaatctccta ctgtatatat ttcaaataga gtagatggaa agactataca taaggttata
    34201 tcaaatgagt ggatggaagc atatgaggct agaataaaag caccaataga agtaagtgag
    34261 taaagtagtg gttacataat taaaatagag ttttataata aggagatttt tatgaatatc
    34321 ataagtaata aaatagatga gttaaaagaa gatttattaa gtgatattat agatattgta
    34381 aaaataccta gtgtcaaagg ggagtcagaa aatggcttcc cttttggcga aaaagtaggg
    34441 gaggcactta ataaagcatt agaaatatca gaaaagttgg gatttaaggt tagaaacttg
    34501 gataattata ttggttatgc agagcatgga gatagtgatg attatgtttg tgtaattgga
    34561 catgtagatg ttgtacatga aggagatggt tggaagcatc agccttataa gggagaagaa
    34621 actaatggaa gaatttatgg acgaggagta ctagacaata aaggacctat aatgtctgcc
    34681 ttatatggat tatatgctat taaagaatta aacttaaaat tagataagag agttagaata
    34741 atatttggta caaatgaaga aagtggattt gaagatatac catattattt agaaaaagaa
    34801 aaagcaccta ttatgggatt tacaccagat tgtaagtatc ctgttgtata tggtgaaaaa
    34861 ggcatggcaa agattagaat aaaaagtaaa atcaattatg aagaagatgt atacctaggt
    34921 tttatagaaa atatgtctga aaatgtgctt gttacatata aagaactgaa tatagaaaat
    34981 agtgatacta tattagatat aaaggtaaaa tacgatttta gttataaatt gaaagatgta
    35041 ttggatgaaa taaaagctag ttttccaaat agtatcgata tagaggtaat ttctaatttt
    35101 aatcctgtat attttgataa agagagtaat cttgttaaaa agcttcagct agcttatgaa
    35161 agggttacat cattagatgg aactcccgta acaactaatg gaggtacgta tgcaaaagta
    35221 atgccaaata tagttccgtt tggaccttca tttccaggac aaaaaggaat agctcataat
    35281 cctgatgaat acatggatat agaagatata atattaaatg caaagatatt tgcaaatgca
    35341 atatatgaat tagcaaagga gtagttatgt tagaaataat aggaatgtca gtagaagacg
    35401 ctaaaattat agaagattgt ggtgcagata gaatagagtt agttagtgct ttaactgaag
    35461 gtggattgac accaagtttt ggtcttatag aaagtgttgt taacagtgta aagatacctg
    35521 tgaacgtaat gataagacat catgcgaaaa gttttgtata cagtaaagaa gatataagta
    35581 taatgcaaaa agatataagt gtggttaaag agattggtgc taatggagtt gtatttggtg
    35641 tattggataa aaacaataat atagatgaga aaaatctaaa tgttttattg aaatgttgtg
    35701 ataatcttga tgttacattt catagagcaa tagatgaatc aaatacaata gatagtgtta
    35761 aaattttgaa ggattatgat aaaattacga atatattaac gtcaggaggg aaaggaagta
    35821 tagttgataa catacaaatg ataaagaata tgatgcttag ttctaatcac ataaaaattc
    35881 ttttaggtgg aggtcttaat tttaataata tagaaaagat aaaggaatta actaaggcaa
    35941 gtaattttca ttttggtaca gcgattagaa taaataacag tccttttgaa gatatagata
    36001 gacaaaagct taaacaactc ataaatataa tttcaagata gtatatgaat ataaaatact
    36061 tagtttaaat aaagagagta agttaattat aatttgggta tatgaatgtt aataggtatt
    36121 aaatatgaaa ttattgttga gtatgcttta taacttttaa ttagttttaa atataaataa
    36181 tgaaagaaaa gatagattat ggaggtttta gagggtttat agttattaaa aaattataaa
    36241 ggtatattgg catataatac acataatttc ctaaaattac catcttatga catgaattca
    36301 catattaata aacaattaat ggagattttt gtggatagaa ataggagtaa aaatagcttt
    36361 aaataaacaa aaacaagagt tattaacagt tttatccaca ttatccacag gtgtttgtaa
    36421 taatattaat ccacataagt atcaatgtaa ctaaaaatga taaataattc tatcaattga
    36481 atagaaaaaa tcataaaagt aaataataaa aagaggatta tgagagttcg tgtagaatat
    36541 attattaaat ataaattttc ttatactggc ataattgaag ggagatgtat ttatgaacat
    36601 aattatatct ggaaaacaaa tcgaattaac tgatgcaata aaaaataaaa tcgaaactaa
    36661 actaagtaag ttagataatt acattcatcc agacactgat gtaaaagtta cagtgagtgc
    36721 gagaaaagca agacaaaaaa tagaagtaac aatagctact gtaaatggtc ctataattag
    36781 agcagaagat atgcaggaaa atttatacac agctatagat gttgtatatg ataaattaag
    36841 taaacaatta aaaaaatata aaaagagatt acaagataaa cataaagaca acaagagtat
    36901 aagattccaa gatgcagaga taaatctagc tgatgaacaa gaggattatg gggatgaaaa
    36961 tcaagaatta gtaattcaaa gacgtaagaa atttagtgtt aagccaatga gtgaagaaga
    37021 agctgtatta cagatggaat taataggaca tgatttttat atgttcaaga acatagattc
    37081 agatgaaata gcagtagttt ataagcgtaa taatggtgga tatggtataa tagaacatga
    37141 ataaagcaat ttagatttaa tcatattagc tatcgataaa taaattatcg atagcttttt
    37201 aaattaatat taaaagtata gtttttatgg taaaatgaat aatagtacaa taaagaacga
    37261 ggagagatgt aaaatatgag ctttatggat aatttattca acatggcaga taaaaaagaa
    37321 ttaaaaaagt tcaataaaac tgttgatata atagattcat tagaacctaa atttgaatct
    37381 atggcagact cggaacttaa aaatatgaca aatatattta aagaaagatt agcaaatggt
    37441 gaaagtatag atgatatact tccagaagct tttgcagtag ttagagaagt ttctaagaga
    37501 gtgttaggac ttagacacta cagagttcaa atgattggag gtatagtact acatcaagga
    37561 agaatagcag aaatgaaaac aggtgaaggt aaaactttgg ttgcaactgc tcctgtttat
    37621 ttgaatgcgc ttactggaaa aggtgtacat gttgtaacag taaatgatta ccttgcaaaa
    37681 cgtgatagag accaaatggc aaaaatctat gagtttttag gaatgagtgt aggcgttatt
    37741 atacacggtc aaaatccaaa agttagaaaa gaacaatatg attgtgatat aacttatggt
    37801 acaaataatg aatatggatt tgactatcta aaggacaata tggtaataca caaagagcaa
    37861 agagttcaaa gaggattaaa ttatgctata gtggatgagg ttgactctat actaatagat
    37921 gaggctagaa caccacttat catatctgga cctggagaca aatcaactca cttatattca
    37981 gatgcaaaca catttgtttt aaccttaaaa ccagatgatt atgaattaga agaaaaagat
    38041 aaggctgtat ctctaacagc atcgggtata caaaaagcag aagtgtattt taatgttgat
    38101 aatataacag atatatctca tacagaatta taccatcata taaatcaagc tttaagagca
    38161 catgtaataa tgaagaaaga tgttgattat gttgctaaag atggagaaat agtaatagta
    38221 gatgagttca caggtagact tatgtttggt agaagatatt cagaaggttt acatcaagca
    38281 atagaggcta aagaaggtct taaaatacaa agagaatcta aaacactagc tactgtaaca
    38341 ttccaaaatt actttagaat gtacaaaaaa ctttctggta tgactggtac agcaaaaaca
    38401 gaagaagaag agtttaaagc aatctacaaa atggatgttt tccaagtacc tactaataag
    38461 cttatgataa gggaagactt accagactgt gtatacaaaa gtgaaatagg taaatttaat
    38521 gctgtagcac aagaaataat tgaaaggcac aaagtcaatc aaccaatact tgtaggtaca
    38581 gtatcaatag aaaaatcaga attattatca caaatactaa agaaaaaggg cataaagcac
    38641 gaggtattaa atgctaagca tcatgataaa gaggcagaaa taatagcaca agctggtaga
    38701 cttggagctg ttacaatagc tactaatatg gctggtcgtg gtacagatat agttctaggt
    38761 ggaaatccag actttttaac taagagagaa atgagaagaa atggatttaa agaagaaata
    38821 gtaaatagag tagatactcc aatagaaggt atacctgtaa aaggtaatga aattctattt
    38881 gaagctagag aagagtatga aaaactattt gaaaagttta agcaacaaac acaagaagaa
    38941 caaaaacaag ttgtagaagc aggtggactt gctataatcg gtacagaaag acacgaatct
    39001 cgaagaatag ataaccagtt gagaggtcgt gctggacgtc aaggtgaccc agggagttca
    39061 agattctata taggtcttga tgatgacctt atgagattgt ttggtagtga tagaatatct
    39121 ggtattgtag ataaaatagg tcttgaagaa gacatgccga tagaacatag aatattatct
    39181 aagtctattg aaggagcaca aaagaaagtc gaaggtaaaa actttggaat aagaaagcat
    39241 gtacttcaat atgatgatgt tatgaataaa caaagagaaa taatatatgc agagagaaaa
    39301 cgtgtattag aaggtgaaga tttacaagaa caaatacaat caatgactca ttctataata
    39361 gaagaagcag ttactcttta tacacaagat aaaggatttg atgaagaagg attcaaagaa
    39421 catatgtata atttgttctt gccaaaaggt agcatagaaa taccagaaat agaaaaactt
    39481 aatccagttg aaataacaga aaaagtttat gaaatagcta tgaagatata tacttcaaag
    39541 gaagaacaag ttggctatga gagaatgaga gaagttgaga gagtaatctt acttcaagct
    39601 gttgataacc attggataga ccatatagat gctatggacc aattacgcca aggtattggt
    39661 cttcgtgctg taggtcagca agacccagtt attgcttata aaatggaagg ttttgatatg
    39721 tttgatgaaa tgaataaaca tatcaaagaa gatactgtaa gatatttatt taatataaca
    39781 atagaaactc cagtggaaag aaaagcagtt gtagatgttg aaaatctatc ttctccatca
    39841 gatggaacac ttccaacaag taaaactgtt aaaaaagatg aaaaggttgg aagaaatgac
    39901 ttatgccctt gtggaagtgg taaaaaatat aaaaactgtt gtggaagata atctcggagg
    39961 attaaatgtt aaagttacaa gagtatagac atagtatgga gcagatggct tcaaatttag
    40021 aagaattgag ggtttctctt tgacatagct tcattgatga aaaatataca aattaatgaa
    40081 gaaaagatga atcaacaaga cttttggaat gataatgaag tcgctcaaag agtacttcaa
    40141 gaaaataaat ctttaaaaga gacattagaa gaatatgaaa gcttaaaaag cttattagaa
    40201 gatatagaag tattaattga aataggttta gaagaagatg atgattctgt agaaagagat
    40261 atagaaaagt ccatagaatc aatggaagaa aaattatctg aaatgaaaat aaagactctt
    40321 ctaaatggag agtatgataa aaataatgct atattatcta taaatgctgg tactggtggc
    40381 ttagatgctc aagattgggc tcaaatgctt ttgagaatgt atataagatg gtcagaaagt
    40441 aagggttata aagttaagct tttagatata atatcagacc ctgaagcagg gataaagaca
    40501 gctacaattc ttgtagaagg aacaaatgct tatgggtatt taaagagtga aaaaggagtt
    40561 catagattag tgagaatatc tccatttgac ccatcaggaa aaagacatac ttcatttgca
    40621 tctatagatg taacaccaga gttagatgaa aatatagaag tagaaattaa tccatcagat
    40681 ttaaagatag acacatatag agcttctgga gctggagggc aacatgtaaa tacgactgat
    40741 tcagcagtta gaataacaca tatccctact ggtgtagtag ttcagtgcca aaatgaaagg
    40801 tctcagcatc taaataagga cagagctatg agacttttaa tggcgaaatt gatagaatta
    40861 aaagagttag aacaaaagga aaaaatagaa gatatacaag gcaaatactc acaaataact
    40921 tggggtagtc aaattaggtc atatgttttt caaccatata aattggttaa ggaccataga
    40981 acaaatgctg agtttggaaa tgtagatagt gtaatgaatg gaaatataga cttgtttatt
    41041 aatgaatact taaaaatgaa taaaatagtt taataaatat gcactgtaat taagatatat
    41101 gtataagaag gttagtgctt aatatgcact tacagcactt aggctgagga cgataaccct
    41161 cagccttcgt tctgttttgt tatacttatg aaaaactaac attaggagtg aataaattgg
    41221 atataaatca aatcttaaaa aaagagttta atcttagaga tgaacaaata aataatacat
    41281 taaaacttat tgatgaagga aatacaatac catttatagc tagatataga aaagaaatga
    41341 ctggcgaaat gagtgatgtt acactaagag aattttatga aaaattaatg tatttgagaa
    41401 atcttcaaag tagaaaagat gatgtagtta gactaataga tgaacaaggg aaattaacag
    41461 atgaaataac acaaaatata gaaaaagcaa aaacattaca agaagtagaa gatatatatg
    41521 ctccatataa acaaaagaaa agaactagag caacaatagc aaaagaaaaa ggattagaaa
    41581 atttagcatt gtcaatacta gagaataatt tagataatat agaaatagag gcaaagaatt
    41641 atcttgatga agagaaagaa gtcctttcta ttgaagatgc tctaaaaggt gctagagata
    41701 taattgcaga actagtctca gatgatgcta agattagaaa gtatataaga gaattagctt
    41761 taagagaagg tatgatagtt agcaaaagtg ctactgatga gaaatcggtt tatgatatgt
    41821 attatgatta tagcgaagca gtaaaaagta tggctccaca tagagttttg gcaataaaca
    41881 gaggagaaaa agaaagcttc ctaaaggtta agttggaaat aaataatgat aaagttttaa
    41941 attacataat aaacgaatat gtaaatgata aaaatttcaa aaataaagaa gaaatcgtaa
    42001 gttcaataga agattcttat aaaagattaa ttttcccatc aatagaaaga gaaataagaa
    42061 atcatttaac agaaatagct caagaaagag ctataagtgt atttggaaag aatgttaaaa
    42121 gtttattgct tcaaccacca gttaaagaca aagtagttat gggatttgac cctgcattta
    42181 gaactggatg taaaatagct gtagtagata aaaatggtaa actactagat tatacaacag
    42241 tatatccaac agaccctcaa aatgatgtag agggagcaaa gaaagtttta aaaggattga
    42301 ttgaaaaata cgatatagat ataatttcaa ttggaaatgg tactgcatct agagaatcag
    42361 aaacctttgt atcagaaatg ataagagaaa tagatagcga agtgcagtat gtgatagtta
    42421 gtgaagcagg agcatctgtt tattcagcat ctgaacttgc aaatgaggaa catccagata
    42481 taaatgtatc aataagagga gctatatcta tagctagaag attacaagac ccattagcag
    42541 agcttgtaaa aatagaccct aaaagtattg gtgttggtca atatcagcat gatttaaaca
    42601 aaaagagatt agaagaagta ctagatggag ttgttgaaga ttctgtaaat agtgttggag
    42661 tagatttaaa tactgcatca tactccctac tagaacatgt tgcaggaata agtaaagcta
    42721 tagcaaagaa tataatagca tatagagaag aaaatggaga ttttacgtca agagcacaat
    42781 tgaaaaaagt aaaaagacta ggacctcaag catttactca atgtgctgga tttatgagaa
    42841 tcttagaggg taaaaatcca ctagataata caggtgtgca tcctgaaagt tatgatatat
    42901 gtaaaaaaat gattgagata attggatatt ctttagatga tgtaaagaat aagaatatag
    42961 gtgaaataga tgaaaaaata aaagaaattg gcttgaggga attaagtgaa aaactggaag
    43021 taggacaagt tacgttaaaa gatatcatag ctgaaatcaa aaaaccagga agagacccaa
    43081 gagaagaagg tataaaacct atacttagaa ctgatgtctt aaaaattgaa gatatacaag
    43141 agggtatgac tttaaaaggt acaataagaa atgttgtaga ctttggtgca tttgtagata
    43201 ttggaataaa aaatgacgga ttagttcata aatcagaaat gagtaatagt tttgtgaaag
    43261 accctatgag tattgttaca gtaggtgata tagtagatgt aaaagtcatt ggaattgact
    43321 taaacaaaaa aagagttgcc ttatcaatga aaaaatagat aagtttatgt atggttatag
    43381 tacttagatt ctatatttgt aaatgagatt actcgagtgt ataaatgtta aaaatttgta
    43441 aaagtatata gtaagaaaat atattaaaat aagaacgata gtcttaaaaa tcaggaggaa
    43501 aatgaatgat ttttataaaa aatggtaaaa taaataccat aacaaatggg ataattcatg
    43561 gagatatact tatagatgaa ggaaaaataa tagaaattgg agaagatttg atagctcctt
    43621 tagatgtaga ggtaatagat gctagtaata aacttgtatt tcctggattt atagatgctc
    43681 atactcactt aggtttatgg gaagatggta taggttttga aggagcagat ggaaatgaag
    43741 agactgaccc aataacacca caattaaatc ctatagatgg aattaatcca atggatagaa
    43801 cttttaaaga agcttttgaa ggtggaataa cttctgtttg tacaacccct ggaagtgcaa
    43861 atgttatggg tggtcaatgt atagctataa agacatgtgg aaaaagaatt gataaaatgg
    43921 taataaaaaa tccagttgca tctaaaattg cttttggaga aaatccaaag agctgttatg
    43981 gtcaggatga taaatctcct caaactagaa tggctatagc tgctttactt agagaaaacc
    44041 taaaaaaagc agaagaatat ttagaggata ttgatatgta tgagagtcat gatgatgaag
    44101 actgtgaaaa acctgaatat gatataaaaa tggaaagttt aataccagtt ttaagaagag
    44161 aaattccttt taaggcacat gctcatagag cagatgatat gtttacagca ataagaattg
    44221 caaaagaatt taatttaaag cttacattag accattgtac agaaggtcat cttattgtag
    44281 atgaattagt ggaagaaggg tttcctgtaa tagtagggcc atctttgtca gaaaggtcta
    44341 aatttgagct tagaaatttg acatttaata cagcaggaat actttcaaat gcaggtcttg
    44401 atgtatgtat aatgacagac catccagtaa taccagttca atatcttcca atatgtgcag
    44461 gtattgcagt aaaacatggt atgaaagaag aaaaagcaat agaatcaatt acgataaatc
    44521 cagctaaggc tttaggaata gaagatagag taggctctat agaaattggt aaagatgcag
    44581 acctagtaat ttgggataat tctccactag agattcaaag taatgtactt tacactataa
    44641 taaatggcaa agtagtgtat gagaaaaaat aacttgacaa ttattaaaaa attaactaat
    44701 ataagagtgt aaggaaaatt aaaaaatcaa agaagatctt cggggcaggg tgaaattccc
    44761 taccggcggt atagcccgcg aactacttag gtggttgatt tggtgagatt ccaaagccga
    44821 cagtaaagtc tggatgagag aagatattta tggaagataa ataagtttat tttagtttgt
    44881 ttaaactata tccataaaaa ctcgaagata gggtcttcga gttttttgtt tttcctaaaa
    44941 aatataaaca tattgattag ggggaaaata attatgcaaa acacagcaaa aagaggcaat
    45001 atgatttcaa caagaacttt agtagtaatg tcaattttat ctgcaatatc ttatttatta
    45061 atgtttattc aagcaccaat accaggtata tttccagatt tcttaaaaat tgacttatca
    45121 gatattccag caatattcgg aggaatgtct ctaggaccat tagttggatt tggaatagtt
    45181 gtagtaaaaa atgtgttaca agcaataaca gcaacaacaa ctggaggaat aggagaattt
    45241 gcgaatatat taattggtgg ttcttatgta atgatacttt gttattcata taagagaagt
    45301 ggagatttaa aaggtgtact gattggtttt gtattaggaa caatatctat gactataatt
    45361 ggttcattag taaattattt tgtaatgttg ccactttatg gtcaacttat gggactagat
    45421 gctataatag gtttaggttc agctataaat cctcaagttc atgatttatt cacttttgta
    45481 atttggatga tagctccatt taatgtgctg aaggctgtta taatatcttt agtaacattg
    45541 ccactttata aaaaaatggg aaatataata aagaaataat tagacaagaa aatataaaat
    45601 taaatgtatt gaatagccat aatttattta taacttcagt cctatattgt gattgatata
    45661 ttaaatatat tatggcttta ttaatttatc aaaaaatgta tataaaataa gaaatattta
    45721 gacaaattta aattttaaaa taaaggaaga attaaaacga ttaactatta aaatatgaaa
    45781 aaggtatcta caatatacag agcgaattta taataaacaa aaaataaagt tattattaaa
    45841 aaactataaa gattaataat caaactttta ataataacta atttaataat gataggggtg
    45901 tatattcatg catttatcta aaaaaataaa aaaattattt ttagatgata aagggtatta
    45961 ttttaatagt aattggaaag atattcatat tggtatttat gatacaaaat taggagattc
    46021 tttaaagtat atcactaatg aatatattga aaatatggaa agtgtaaaat acgattatcg
    46081 tgaattaaaa aatatagaaa atcaaactga tggtatgtgt attttagcaa taaggcagaa
    46141 ttacaaggca ttagagtatg taaaaaatca aaccgaagaa ttatgtttag aagcaataaa
    46201 gtataattat aaagcacttg aatatgtaaa agaacaaaca gaatacttgt gtcttgaagc
    46261 tataaaaaaa gattgtaatg cacttaagta tgtacgaaat aaaacagaag ggcttattat
    46321 aaaagcaata agtcattctt ccaatataga tgttgtaagt atactaaagg ctttagagac
    46381 tcaaacaaga aggatatgtt tagaagcaat taaaaaagat ggcaggtgtc ttgcatacgt
    46441 tagagaacag agtgaagaat tatgtataga ggccattaag caaaattata aagcattaaa
    46501 atatgtaaaa aatcaaacgg aaaaaatgtg tatagaatcc gtaagacaaa atggtatggc
    46561 attacaatat gtaaataaac aaactgataa aatatgtata gaagctgtca aacaagatgg
    46621 aagaagtata caatttgtca acaataagac agaagaaata tgtataaatg ctataagata
    46681 tttaaataaa aaatataata ttaaagatgt actaagttac atagataagt atacagaaga
    46741 tatatgtata gagattgtaa gacaaaatgg aaaaatgctt atgtatataa aaaatcaaac
    46801 agaaaaaatg tgtattgaag cagtaaaaga gaactataag tctcttaagt atgtaaaaga
    46861 gcaatctgag agaatatgta aagaagcatt gaagcaaaac cataaagcaa aagagtatgt
    46921 aaaaattgct attgatgatt gtatataagg tgtagataca gccatcaata gtgaaagata
    46981 aaaaaagata aagacaagta ctttataata atctaggctt atactataat taattaagca
    47041 gtgatataaa ttcacatgac gattatatca aaatggagat gaattgatgg caaaaatata
    47101 tttagaaaat gaaaataaaa ctagagaaat aggatataaa ttaggtaaac ttttaaaaga
    47161 aggcagtgtt atctgtttag taggagattt aggagctggt aaaactacaa tgacacaaag
    47221 tttggcagat tcattaggga tagaagatta tataacaagt cctactttta ctataataaa
    47281 tgaatatgaa ggaaaaatac ctttgtatca ttttgatgtt tatagaatag gtagtagtga
    47341 tgaaatgtat gatattggtt atgatgaata tgtaaattca aatggaatct gtataataga
    47401 atgggctaat ctaatagaag atatacttcc aaaagaatat ttgaatatag aattgagata
    47461 taaagatgaa ggaagagaaa tgatattaac tccaaaagga gagttttata aagagatagt
    47521 tgaggagttg attaaataat gaaaatacta ggtatggata cgtcttctat ggcagcaagt
    47581 gtagcagttg ttgaagatga taacttaata tgtgagttta cagtaaacaa caaaaaaact
    47641 cattcacaaa agcttatgcc aatgatagaa aatatgttga gtatgagtga tttaagtata
    47701 aaagatatgg atttattagc tgtatgtata ggtccaggtt cgtttacagg acttagaata
    47761 ggtatggcta cagtaaaagc tatggcccat gtaaataata taccaataat agcagtaaat
    47821 tctttggaat ctctagcaaa taacataaat ttctgtgata gaaagatatg ttgtatatta
    47881 gatgcgcaga aaaatcaagt ttattcagct aaatacaagt ttgaaaatgg agagatgata
    47941 gaattagatg gtgttgatgt tgtagatttt gatgctttag tagatgaaat tgtatcaact
    48001 aatgaagaat ttataatagt tggagaagct gtatacaaat ataaagacaa gttagagaat
    48061 ataaaaaata taaaaatacc ttcaccagct aataatgtat ctaacgcagg aagcttatgc
    48121 tctttagcat taaataaata taataaaaat atagatgtac atacttgtta tacgataaat
    48181 cctatgtata tcagaaaatc tcaagctgaa gtacaatatg atgaaaaaat gaagaggcta
    48241 aataatggaa gataatacaa aactaatagt agatgatata aaaatagaag aaatgactac
    48301 agaagatata gatgaagttt ttgaagtaga aaaaaattgt tttgaagatt attggtcaaa
    48361 agagtctttt agaaaagagt tgtctaatga agtagcaagg tatatagtag ctaagttaaa
    48421 tggaaaaatt gtcggatatg tgggaatttg gcttatactt gatgaagggc atataaataa
    48481 tgtggctgtt catagtgact atagagggaa aaaaataggg gacaagttga taaaaggcat
    48541 agttgattta tgtaaagata ataatattgc atctatgaca ttagaagtta gagcatcaaa
    48601 taaaatagca caaaatttat atagaaaata tggatttaaa atgggtggaa taagaaaaga
    48661 atactacagt gataataaag aagatgcaat tataatgtgg aaccaattaa aagaggtgta
    48721 gagtttatga gtgatataat aacattagct atagagagta gttgtgacga aacagctgca
    48781 tcagttttaa aaaatggtag agaaatactt tcaaacataa tctctactca aatcgagaca
    48841 cataaaaaat ttggtggtgt agttccagaa gtggcctcaa gaaaacatgt ggaaaatatt
    48901 gatatagttg ttcaagaagc tttagacaaa gcaaatatag gttttaatga tatagaccat
    48961 atcgcagtta catatggacc tgggctagta ggtgctttat tggttggtct atcttatgct
    49021 aaagcacttg catatacttt gaatattcca cttgtaggag taaatcatat agaagggcat
    49081 ctaagtgcaa actatataga gcataaggat ttaaaacctc cttttataac attaatagta
    49141 tctggaggtc atactcactt ggttgaagta aaagattatg gcaagtatga aattttagga
    49201 aaaacaagag atgatgcatc tggagaagca tttgataaga tttcaagagc tatgaattta
    49261 ggctatccag gaggtcctat tattgataat ctggccaaga atggaaataa acatgctata
    49321 gaatttccaa gagcctattt agaagaagat agctatgatt ttagttttag tggattaaaa
    49381 tcttctgtat taaattatct aaatggaaaa agaatgaaaa atgaagaaat agtagttgaa
    49441 gatgtagcag catctttcca agaggctgta gtagaggttt tatctactaa agcactaaaa
    49501 gcagtaaaag acaaaggata caatatcata actctttctg gtggggttgc ttctaattcg
    49561 gggcttagag ctaaaataac agagcttgct aaagacaatg gtattactgt taagtatcct
    49621 cctctaattt tatgcacaga taatgcagct atgatagggt gtgcaggata ttataatttt
    49681 ataaacggga aaacgcatga tatgagttta aatgcagttc caaatttaaa gataaatcag
    49741 tagagttaga tgaatttgta aatataaaag tattgtttca aaaaagtaag tagaagtgaa
    49801 attaaatata ataaaaataa atatagtata tattaaaact tgaagtaaaa ctatttataa
    49861 tctttatatt ccaatgaatt gcaacaaatt ttaggatata cagattgtct ttggcttaga
    49921 tttgcttcaa gtttaatttt ttctatagaa agattatttt aaaaagtggg taatataccc
    49981 ttttttttca ttcttaaaaa gttttatact aattatagaa agattaagga ggggaagaaa
    50041 tgagtcaaag taaagaagac aaaataagaa gtattttgga agcaaaaaat attaaatcaa
    50101 attttcaaaa taaagaaaat ttaagtgaat ttaatgaaaa aaaagcaagt aaaagagcag
    50161 aagacttatt agatgtatat tataatacat tatctactgc tgatatggaa tttccatatt
    50221 ggtataatag agaatataga aaatcagatg gtgatatacc agtagttaga agagctaaag
    50281 ctcttaaagc tgctttttca catatgacac caaatataat acctggtgag aaaatagtaa
    50341 tgcaaaagac acgccattat agaggttctt ttccaatgcc atgggtaagt gaaagcttct
    50401 ttgttgctca aggagaacaa atgagagaag aggcaaagaa attagccagt aacacagctg
    50461 atgaacttac aaaatttggg tctggtggag gaaatgttac tgaaagtttt ggaaatgtcg
    50521 tttcaatagc tggtaaattc ggaatgagaa aagaagaagt acctgtactt gtaaaaatgg
    50581 caaaggaatg ggttggaaag tctgttgaag atttaggttt tcactatgaa aaaatgatgc
    50641 cagattatga tttaaaagaa aacctaatga gtacacttat atgcatgttt gattcagggt
    50701 atacacttcc tcaaggtaga gaagttataa attattttta tcctttaaat tatggattag
    50761 atggaattat agaaatggca aaagaatgta aaaaggcagt tgcaggaaat gcatctggag
    50821 atgggcttat tggtatggac cgtctatatt tttatgaggc tgttattcaa gttattgaag
    50881 gattacaaac ttggatttta aattatgcaa aacatgcaaa atatttagaa agtatagaga
    50941 cagatttaga agctaaaaaa gaatactcag atttagtgga gatattagaa catattgcac
    51001 ataaacaacc tcgtacattt agggaagctc ttcagttgac ttatacaatt catatagcat
    51061 cagtaaatga ggatgctata tctggtatgt ctataggacg ttttggtcaa attttatatc
    51121 cttggtatga acaagatata gaaaaaggac taattacaaa agaagaggtt atcgaattat
    51181 tagagcttta tagaataaaa atcacttgta ttgactgttt tgcttcagcg ggcgtaaatg
    51241 gaggagtact atcaggcaat acatttaata ctttatctat aggtggatta aaagaagatg
    51301 gttctacagg agctaatgaa ctagaagagt tattattaga agcaagtatg agatgtagaa
    51361 ctcctcaacc tagtttaact atgctatatg atgaaaagct tccagaagat ttcttaatga
    51421 aagctgctga atgtacaaag cttggttctg gttatccagc atgggtaaac aactcaaatg
    51481 gaacaacatt tatgatgaaa caatttgctg atgaaggtat gactgttgaa gaagcaagag
    51541 catttgcatt aggtggatgt ttggaaacgt ctccagggtg ttggaaacag ttaactttaa
    51601 acggaaaaac atactctatt gcaggtggag caggtcaatc tgctggctct ggagttcact
    51661 ttatagctaa tccaaaaatt ttagaacttg ttcttatgaa tggtaaagac tatcgtatga
    51721 atatacaagt atttgagcct cataataagc cattagatac ttatgaagaa gtcatagaag
    51781 tatttaaaga ttattataaa caagcaataa atgttttaga aagagcaaat aacattgagt
    51841 tagatatatg gagaaaattt gatacttcta taataaattc actactaaag ccagactgtt
    51901 tagacaaagg tcaacatata ggaaatatgg gatatcgtta taatgcaaca ttaaacgtag
    51961 aaacttgtgg tactgttact atggtcaatt catttgcagc tcttaagaaa cttgtatatg
    52021 atgacaaagc atttacaata gaggaaatga aggatgccat attaaataat tttggattta
    52081 aagatgcatt agaagtagga aattattcta tggcagacca agtaaaagta gataagactg
    52141 gtaaatatga tgctatttat aaggcctgtc ttgatgcacc taaatatgga aataatgatt
    52201 tgtatgcaga taatattctt aaaaactatg aggtatggtt atcaaaagta tgtgaagaag
    52261 cacaatcttt atatgctaag aagatgtacc cttgccaaat atctgtttct acacatggtc
    52321 cacagggagc tgctaccttg gctactccag atggtagact aagtggaaca acatattcag
    52381 atggttcagt ctctgcatat gcaggaacag ataaaaatgg agtatatgca ttatttgaat
    52441 ctgcaactat ttgggaccaa gcagtagttc aaaattctca gatgaattta aaacttcatc
    52501 caactactat aaaaggacaa caaggaacta aaaaattatt agatttaaca agaagttatt
    52561 taagaaaagg tgggttccat attcaatata atgttgtaga ttcagaaaca ttaaaagatg
    52621 cacaaaaaaa tcctgacaat tatcgtcaat taatggtacg tgttgctggg tttactcaat
    52681 attggtgtga attaggtaaa ccaatacaag atgaagtaat tgctagaaca gagtatgaag
    52741 gggtgtaaaa tatgagaaag catagtgatt gtatgaattt ttgtgcagta gatgcaacca
    52801 aaggaatttg tagattatca aaacaaatga ttaatttaga tgatgcagca tgtccagaga
    52861 taaaagtaat gccaaaatgt aaaaattgta aaaattttgt tgaagctaat gatgaaggta
    52921 taggcaaatg tgttggccta gagaaagaag actgggtata ttcaacattg aatgcaatta
    52981 cttgtgaagg acatgtgttt aatgagtagt caaaagcaat tagaaggcat gatttttgat
    53041 gtacaaagct tttcagttca tgatggtcca ggttgtagaa caactgtatt tttaaatgga
    53101 tgtccactga gttgtaaatg gtgtgcaaat ccagaaagtt ggactgtaag accacatatg
    53161 atgtttagtg aattatcttg tcaatatgaa aatggatgta ctgtatgtca tggtaagtgt
    53221 aaaaatggtg cattgagctt taatcttgat aataagccag ttatagattg gaacatctgt
    53281 aaggactgtg aaagttttga atgcgtcaac tcatgttatt ataatgcgtt taaattatgt
    53341 gcaaaacctt acactgtaga tgaacttgtg caggtaatta aacgtgattc taacaattgg
    53401 agaagtaatg gaggagtaac atttagtgga ggtgagccac tacttcagca tgaattttta
    53461 catgaagtat tattaaagtg tcatgaggta aatatacaca ctgccattga aacgagtgca
    53521 tgtgtatcaa atgaagtttt taataaaata tttaacgata ttgattttgc atttattgat
    53581 ataaagcata tggatagaga aaaacacaaa gaacaaacag gtgtgtataa tgatttaata
    53641 ttagaaaata tatcaaacct tgcaaattct gattggaatg gaagattagt acttagagta
    53701 ccagttatct ctgggtttaa tgatagtgat gaaaatataa gtgatattat atcttttatg
    53761 cacaaaaata atttggtaga aattaatcta ttaccatttc acagattagg agaatcaaaa
    53821 tggactcaat taggcaagga atatgagtat tctgataagg gtgatgttga tgaaggtcat
    53881 cttgaagaat tacaagatat atttttggat aatggtatag cttgttatgt tggtcatgag
    53941 acagctttct aaaattaaat acaagtttta attaaaaaag gatgttacac taaaagctag
    54001 agttacatcc ttttttatgt ggtttttatg tagaaataat taagtaaagt tttatatgtt
    54061 ttatatattg tttatattgc tttatgtcca taaatattgc tttaaatata ctttatatat
    54121 tttttatagt ttaaattaca gttagagaat atattacgtt tacttcattg aagcagaagt
    54181 tttgtggtaa aatactacta tgaaaaaatt taatagaata tattttagaa acaactaaaa
    54241 ataatagtta ggaggaagac atctatatga acaaatcatg gagcaacttg attattaaga
    54301 ataaagacag aaaagtacgt tcagggtgga ttattatagc tgttatgact accttttaca
    54361 tacttcagta ttatttaagc atgatacttg tggaaataat aagaaaaatc ctggttgcta
    54421 caggtgacat taatttaaaa acaaactatt tttcagaata tgctaattgg ttaaatgatg
    54481 ttgggttaca gattgtattt caaattctaa cagattcact tatgattatt attcctataa
    54541 ttgtatggag atttattatg aaaaatccta ttagtgaaat gggattacat tcttatagaa
    54601 ttaagaaaaa agaaggatat gtaggaatgt tattaggaat atttaattgt acagtaatct
    54661 ttattataac aataacaatt ggtggtggtc atgttacttc atgggtacca aaaatttcac
    54721 ctttaacagt ttcttggata cttgtcttta ttttagttgc ttttgcagaa gaaattttaa
    54781 atcgtggttt ttttatggca gttttacgaa gatgtaaaaa tatttatttt ataatgattg
    54841 ttccatctgt tatttttggg ttgattcata tatggaatcc tgatgttact tttttgtctg
    54901 taattaatat tataattatt gggattcttt tttcatatat gtttataaag tcgtcgaata
    54961 tatggatgtg tataggttat cattttacat ggaatgtatt tcaggggatt atatatggta
    55021 tgcctgtaag tggacttcag gttccaggga ttataactac acaaatcact catggtaatc
    55081 tattaaatgg tggtatgttt ggtattgaag gtggaatttt gactactttt gttaatctac
    55141 ttagctttat atttgtatgg tattactata gagattctaa gtatgatttt gttagtgata
    55201 aagtaaatgt gaccaatatc aagaattagt tgattataat aaattttaat aatatcttct
    55261 aagcttaaag tattctgtag gattgttgga aatttacaaa aatataaaaa taacttggat
    55321 attctattta ctccaagtta tttttatatt cttttgtaaa tagaaatgga acataaaaaa
    55381 ttaaaacaac catagatact attagtatat catggtaagt gatagttgat tctttagaat
    55441 ttgtgataag aaaagcacta ttatttaaaa catgaattat agcacaaaac cagatattct
    55501 tagtttttat ataaagatat cctaaaaata ttgaaattcc aactatatgt attgaacgta
    55561 atattattcc taatattggc acttcaggtg tatataatgt aaatattagt ggtaagtgcc
    55621 acaagctcca acacatacct aatattataa ctcctaactt tttaccaaat ttatcaaaaa
    55681 aaatattctg taaaaaacct ctccaggcat attcttcact aaaaaaaata taaatagtgg
    55741 ttaatgatgt tattggagta aatataaatt ttatgatacc actataatta ggttgagccc
    55801 cttgtagtat tagtataaat gatgttggaa caattacaga aatcataaag taaataatta
    55861 ataaagaacc tagtttaata ttttttacag gatataaatt ttttttattt gatgaatata
    55921 ttataattga taagctactt ataaaagtta atattaggtt tataattata aattcattat
    55981 tatttattag atttaataac ttaagaacaa ttaataatga ataaataaga aaaaataata
    56041 tgattagtga ataaaattca tacatatcat tatttaatcc ttcagtataa aactttgcaa
    56101 tagcaactga agatagaggt aatatcatca tgaatgatgc aaagttttct ggatcaataa
    56161 atttattata atataacagt aaacctaatg aataagttaa accaaagttt ataaagaaaa
    56221 agataataat ttgtattttt tttcttttta tttcattttt aataaatact gggtttagaa
    56281 tatttatcca tattaatttt aagttcatta atttaatact cctttacaat atagattctt
    56341 aactaaatta aaatatttta ttgaatatta taaattcatg acagtcaata ttattgaaaa
    56401 gtaacttata aaattatata taaataataa aattaa
//
LOCUS       DAEPUT010000016        56290 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.016, whole genome shotgun sequence.
ACCESSION   DAEPUT010000016 DAEPUT010000000
VERSION     DAEPUT010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56290
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.016"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            297..2486
                     /locus_tag="KRL22_001105"
     CDS             297..2486
                     /locus_tag="KRL22_001105"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HBH1271608.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            2554..3321
                     /locus_tag="KRL22_001106"
     CDS             2554..3321
                     /locus_tag="KRL22_001106"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBH1271609.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            3379..4395
                     /locus_tag="KRL22_001107"
     CDS             3379..4395
                     /locus_tag="KRL22_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH1271610.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            4461..4709
                     /locus_tag="KRL22_001108"
     CDS             4461..4709
                     /locus_tag="KRL22_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271611.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(4885..5382)
                     /locus_tag="KRL22_001109"
     CDS             complement(4885..5382)
                     /locus_tag="KRL22_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH1271612.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(5626..6690)
                     /locus_tag="KRL22_001110"
     CDS             complement(5626..6690)
                     /locus_tag="KRL22_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1271613.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            complement(6693..7790)
                     /locus_tag="KRL22_001111"
     CDS             complement(6693..7790)
                     /locus_tag="KRL22_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1271614.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKEKYKWREV"
     gene            complement(7804..8739)
                     /locus_tag="KRL22_001112"
     CDS             complement(7804..8739)
                     /locus_tag="KRL22_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271615.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQISGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            complement(8868..9515)
                     /locus_tag="KRL22_001113"
     CDS             complement(8868..9515)
                     /locus_tag="KRL22_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271616.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            complement(9508..10671)
                     /locus_tag="KRL22_001114"
     CDS             complement(9508..10671)
                     /locus_tag="KRL22_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1271617.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSRHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            10855..11199
                     /locus_tag="KRL22_001115"
     CDS             10855..11199
                     /locus_tag="KRL22_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBH1271618.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVASYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            11230..12831
                     /locus_tag="KRL22_001116"
     CDS             11230..12831
                     /locus_tag="KRL22_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HBH1271619.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KEFVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            12850..13950
                     /gene="dprA"
                     /locus_tag="KRL22_001117"
     CDS             12850..13950
                     /gene="dprA"
                     /locus_tag="KRL22_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBH1271620.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YRGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            13983..16070
                     /gene="topA"
                     /locus_tag="KRL22_001118"
     CDS             13983..16070
                     /gene="topA"
                     /locus_tag="KRL22_001118"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBH1271621.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGKFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            16235..17020
                     /gene="codY"
                     /locus_tag="KRL22_001119"
     CDS             16235..17020
                     /gene="codY"
                     /locus_tag="KRL22_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBH1271622.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            17127..18392
                     /locus_tag="KRL22_001120"
     CDS             17127..18392
                     /locus_tag="KRL22_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBH1271623.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            18423..19193
                     /locus_tag="KRL22_001121"
     CDS             18423..19193
                     /locus_tag="KRL22_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1271624.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            19302..19748
                     /locus_tag="KRL22_001122"
     CDS             19302..19748
                     /locus_tag="KRL22_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH1271625.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            19766..20959
                     /gene="nifS"
                     /locus_tag="KRL22_001123"
     CDS             19766..20959
                     /gene="nifS"
                     /locus_tag="KRL22_001123"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HBH1271626.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            21013..21453
                     /gene="nifU"
                     /locus_tag="KRL22_001124"
     CDS             21013..21453
                     /gene="nifU"
                     /locus_tag="KRL22_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HBH1271627.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            21742..22821
                     /gene="mnmA"
                     /locus_tag="KRL22_001125"
     CDS             21742..22821
                     /gene="mnmA"
                     /locus_tag="KRL22_001125"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBH1271628.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    22964..23202
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            23270..25909
                     /gene="alaS"
                     /locus_tag="KRL22_001126"
     CDS             23270..25909
                     /gene="alaS"
                     /locus_tag="KRL22_001126"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBH1271629.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            25934..26191
                     /locus_tag="KRL22_001127"
     CDS             25934..26191
                     /locus_tag="KRL22_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBH1271630.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            26201..28372
                     /locus_tag="KRL22_001128"
     CDS             26201..28372
                     /locus_tag="KRL22_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271631.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            28578..29003
                     /gene="ruvX"
                     /locus_tag="KRL22_001129"
     CDS             28578..29003
                     /gene="ruvX"
                     /locus_tag="KRL22_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBH1271632.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            29081..29368
                     /locus_tag="KRL22_001130"
     CDS             29081..29368
                     /locus_tag="KRL22_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBH1271633.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            29650..30108
                     /locus_tag="KRL22_001131"
     CDS             29650..30108
                     /locus_tag="KRL22_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH1271634.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(30225..30962)
                     /locus_tag="KRL22_001132"
     CDS             complement(30225..30962)
                     /locus_tag="KRL22_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH1271635.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            31179..32855
                     /locus_tag="KRL22_001133"
     CDS             31179..32855
                     /locus_tag="KRL22_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBH1271636.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            33062..33262
                     /locus_tag="KRL22_001134"
     CDS             33062..33262
                     /locus_tag="KRL22_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HBH1271637.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            33316..34479
                     /locus_tag="KRL22_001135"
     CDS             33316..34479
                     /locus_tag="KRL22_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1271638.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(34690..35112)
                     /locus_tag="KRL22_001136"
     CDS             complement(34690..35112)
                     /locus_tag="KRL22_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HBH1271639.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(35133..35969)
                     /locus_tag="KRL22_001137"
     CDS             complement(35133..35969)
                     /locus_tag="KRL22_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1271640.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            36267..36863
                     /locus_tag="KRL22_001138"
     CDS             36267..36863
                     /locus_tag="KRL22_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HBH1271641.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLLYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILTPIYAVLLKIVYLFV"
     gene            36893..37612
                     /locus_tag="KRL22_001139"
     CDS             36893..37612
                     /locus_tag="KRL22_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBH1271642.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKEKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            37614..38153
                     /gene="scpB"
                     /locus_tag="KRL22_001140"
     CDS             37614..38153
                     /gene="scpB"
                     /locus_tag="KRL22_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBH1271643.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            38315..38944
                     /locus_tag="KRL22_001141"
     CDS             38315..38944
                     /locus_tag="KRL22_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HBH1271644.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            38898..39326
                     /gene="ytfJ"
                     /locus_tag="KRL22_001142"
     CDS             38898..39326
                     /gene="ytfJ"
                     /locus_tag="KRL22_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HBH1271645.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            39574..40014
                     /locus_tag="KRL22_001143"
     CDS             39574..40014
                     /locus_tag="KRL22_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1271646.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            40030..41481
                     /locus_tag="KRL22_001144"
     CDS             40030..41481
                     /locus_tag="KRL22_001144"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBH1271647.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLIENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGSFVEGILLGNYKFDKYKTKIKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(41572..42240)
                     /locus_tag="KRL22_001145"
     CDS             complement(41572..42240)
                     /locus_tag="KRL22_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HBH1271648.1"
                     /translation="MFKIFLFSSEQFVNLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            42509..42649
                     /locus_tag="KRL22_001146"
     CDS             42509..42649
                     /locus_tag="KRL22_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271649.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(42824..43144)
                     /locus_tag="KRL22_001147"
     CDS             complement(42824..43144)
                     /locus_tag="KRL22_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH1271650.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(43264..44001)
                     /locus_tag="KRL22_001148"
     CDS             complement(43264..44001)
                     /locus_tag="KRL22_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBH1271651.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            44216..46039
                     /gene="acd"
                     /locus_tag="KRL22_001149"
     CDS             44216..46039
                     /gene="acd"
                     /locus_tag="KRL22_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HBH1271652.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESNGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            46254..50552
                     /locus_tag="KRL22_001150"
     CDS             46254..50552
                     /locus_tag="KRL22_001150"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBH1271653.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            50756..51217
                     /locus_tag="KRL22_001151"
     CDS             50756..51217
                     /locus_tag="KRL22_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBH1271654.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            51247..52401
                     /gene="nusA"
                     /locus_tag="KRL22_001152"
     CDS             51247..52401
                     /gene="nusA"
                     /locus_tag="KRL22_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBH1271655.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            52408..52689
                     /locus_tag="KRL22_001153"
     CDS             52408..52689
                     /locus_tag="KRL22_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBH1271656.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            52679..52990
                     /locus_tag="KRL22_001154"
     CDS             52679..52990
                     /locus_tag="KRL22_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HBH1271657.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            53012..54952
                     /gene="infB"
                     /locus_tag="KRL22_001155"
     CDS             53012..54952
                     /gene="infB"
                     /locus_tag="KRL22_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBH1271658.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            54995..55375
                     /gene="rbfA"
                     /locus_tag="KRL22_001156"
     CDS             54995..55375
                     /gene="rbfA"
                     /locus_tag="KRL22_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBH1271659.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            55356..56033
                     /locus_tag="KRL22_001157"
                     /pseudo
     CDS             55356..56033
                     /locus_tag="KRL22_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
BASE COUNT        22576 a         6055 c         9894 g        17765 t
ORIGIN      
        1 tttattttct aaatacttat taattaatca aagttaaaat gaaaaaaata taaaaaaata
       61 aagtatataa gagtataatt tgacttttat atactttttt atattatttt tgagtttttt
      121 aggaagatat tttacaagtt aagaaaacta taaggagtgt tatattgaat ataaaatagt
      181 ataatatata ttatgttaga taattaatat gaaaatatac aaatatataa aaagtttgtt
      241 tagagttata gttaatgtgt gtattaattt aatactaatt tattggaggt ttaaaaatga
      301 aatacataat aaaaagagat ggtacaaaag aactttttag taaaagtaag attgaagatg
      361 ctgtctataa agctagtata aatagtgaag gtggagtaga tagagagttg gcatatgata
      421 tatcaagaaa aatagctaat gactataatt ctatggaaaa atgcttatcc gtagaagaaa
      481 tacaagatat agttgaagta ctacttatgg aatcaaatag aaaagatata gcaaaacact
      541 acatattata tagagaaaga cgctctgaaa taaggactaa agcttgggag tttgatgaat
      601 tacaaaaatc aatatggaag aacaagtata gacataatgg tgagagtttt gatgaatgga
      661 taaagagaat ttcaaataat agttcaagaa tatcaaaact aataagacaa aaaagatttc
      721 tatttgctgg aagaatttta gcaaatagag gattacagaa agaaggaaaa aaagtaacat
      781 attctaattg ttatgtaata gaaccaccaa aagatagcat agaagatata tttgatactg
      841 caaaaaaact tgctagaact tttagttatg gtggaggagt tggaattgat atttcaaagc
      901 taagaccaaa aggagcgaaa gttaacaatg ctgcaaaaca tacgactgga gcagtctctt
      961 ttatggaact ttacagtatg acaactggct taattggtca aagagggaga agaggagctc
     1021 ttatgatttc tatggatgta aatcatccag agatagaaga ctttatagat ataaaaacag
     1081 atttggagaa ggttactaaa gcaaatattt ctgtaagagt aacagatgaa tttatgcaag
     1141 ctgtaagaga aaaaaagtta tataattgta cttttgaagt tgaaactact ggagaaaaaa
     1201 tagttaagat agtaaatgct tatgatttat ttaataaatt tgtgaaaaat aactgggatt
     1261 atgcagaacc aggtatattg ttttgggata aaataaaaac atataatttt atgagtgaag
     1321 ataagaactt ttgcttttca ggagtaaatc cttgtgcaga agaaccactt ccaagtggag
     1381 gaagttgtct acttggctca ataaacttgt cagagtttat aatacaacca tttggtgaac
     1441 atgctacttt tgatattaat aaattaaaat cttgcgttag agaagctgta gtagctttaa
     1501 atgatgtctt agatgaggga ttgaacttgc atccattaca agaacaaaga gatagtgtac
     1561 ataagtatag acagataggt ttaggtgtaa tgggtatagc tgatatgctt ataaaaatgg
     1621 gaataagata tggttctgat gaatctttag aactatgtga tttaattggt aagactatgt
     1681 taaatgaagc tgtgaagcaa tcagcattaa ttgctaaaga atatggaaca tttagtgagt
     1741 ataaatatga aaatatttct aaatctaagt tttttataga aaatctaaat gaagacacta
     1801 aggaaatggt taaaaagtat gggcttagaa attcacaact tttaaccata cctcctacag
     1861 gttccatatc tacaatgata ggtatcagtg gtggaataga acctatattt aatctttcat
     1921 atataagaaa aactgaaagc ttgcatgatg aggatgtgta ttataaagta tatactccaa
     1981 ttgttaaaga gtatatggac aagaaaggta ttacagatga agaatgttta ccagattttt
     2041 ttgttactgc tatgaatata ggatatgaag aaagaataaa catgcaaaaa gtatggcaaa
     2101 agtatattga tgcttctata tcatctacaa taaatatacc ttttgaaact acagttgaag
     2161 atgttttcaa tatatatatt aaggcatggg aggctggtct taaaggagta acaatattta
     2221 gagatggatg taaaaggagt ggaattttaa taaatgaaaa aaaggaagaa aataataaag
     2281 aagataaaaa agaaaatagt aaaaaagaat attataaaaa taataaaaaa gaaaaagata
     2341 ataaagatga aaaagccaaa gaaataataa ataaaaattt tgaagaagat gaaaaatttg
     2401 tgtgccctga gtgtggaagt gaaggaattg cacatacagg tggatgtagt atatgtttaa
     2461 aatgtggcta tagtggatgc aattaaactc taattaaaaa attttaatat atttaaaaat
     2521 taaattttta aaaacgaaag atgagggaat ggtatgcagg ataaaagtgt gagggagatt
     2581 aaagaaataa tagagacttt ggaagtagaa aaatatatgg aatatataga gctgttaaga
     2641 gttgatgaaa gaaaatctgt acaaggtcta gctataaaac tagcaaaaaa gctggataat
     2701 attagaaaag aagaagaaag attggaaact ataaatatat ttgagaacga aggctatgat
     2761 aaaggttatt tatatattgg aggaattgat gaggcgggaa gaggaccact tgctggacct
     2821 gttgtagctt ctgttgtagt atttaaaaaa gataccaaaa tagaaggtgt aaatgactct
     2881 aagaaactga gtgaggcaaa aagagatgaa ctttttgaag taataaaaga agaagcacta
     2941 gattatggaa taggtatagt aaacaatgaa gaaatagatg aatttaatat attaaatgct
     3001 acatatatgg caatgaaaaa ggctataaat tgtttaaaaa aagcaccaga ttatttatta
     3061 gttgatgcag caacaatacc aggtattgac atatctcaaa atccaattgt gaaaggagat
     3121 tcaaaatcta tatcaatagc agcagcaagt atacttgcta aagttactag ggatagtata
     3181 atgtaccaat atgatagagt atacccagaa tatgggttta aatctcacaa aggatatgga
     3241 actaaagaac actatgaagc tattgaaaaa tatggcataa ctcctatcca cagaaaaagt
     3301 tttttgaaaa atatactgta aatataatat gatataatgt atataatata aattactata
     3361 gttaatgggg gattaaagat ggaatataat gaattattaa aaagtgctag agaaaattta
     3421 aatggaagtt gtaaagtttg taaggtttgt aatggggttg cttgtgcagg tgaagtgcct
     3481 ggcatgggag gtaaaggaag tggttcttct tttatagaaa atagcaagag tttagaaaaa
     3541 gtaaaagtaa atatgagagt aatacatgat gtatcaaatc ctgatacatc tatagagatg
     3601 tttggaaaga aaatgagtgc acctatattt gcagctccag taacaggaac tactttaaat
     3661 atgggtggaa aaattaatga aagagattac atagaaccag tagttgcagg atgtgctaat
     3721 agtggtattt atgcaatggt tggtgatacg gcagtagatg cttttttaat ggaaaattta
     3781 gatgtagtca aaaagtataa tggagctgga attgtattta ttaaaccttg ggataatgaa
     3841 aatattataa aaaagataag attagctgaa gaagctggtg catttgcagt tggagttgat
     3901 atagatgcct gtggtctagt aactttatca ttacatggaa aaccagtact tcctaaaaat
     3961 gttaaacaaa taaaggagtt agtaaagtct actaaactac catttatatt gaaaggtata
     4021 atgactgttg aagatgcttt aatggcagta gaagcaggtg tggatgcaat agtcgtatca
     4081 aatcatggag gaagagtgct tgactgtaca ccaggagcat gtgaagtttt accaaaaatt
     4141 gctgatgctg ttaaaggtaa agttacaata cttgcagatg gtggagtgag aactggttta
     4201 gacgtactaa aaatgatagg tttaggtgca gatgcagtat taataggaag accttttgtg
     4261 actgcttctt ttggtggtgc aactgatggt gtagaaactt atgtaaataa acttcaatca
     4321 gagctaagta gttctatgat attaactgga tgtcaaacta taaaagatat tgatggaaaa
     4381 gttatataca aataaaattt tatacaaaaa agaggaaaaa tcattttaat gtagaataat
     4441 tgtacaaagg gggaatttat atgagtagaa aagcttatga agaagcctta gtagaattag
     4501 aaaaatttat tgatgaaaga aaagaaataa ttaaaagtgc ggaggactgt attgataagt
     4561 acatagttga cagaacgcta ccttttgatt acaaagataa atgtgtggaa tggcaacaag
     4621 agttacttga tattgcagag gcacaagttt tagaagcaaa tgaattaagt gtattattac
     4681 aagagaaaaa agaacttgaa gaagattaaa ttttattagc taagagtaaa tcagtaatat
     4741 gatttactct tagttttttt tatttgaata aaatacatct atctaattga gataacttta
     4801 ttaatattag attaggcagt ttaaaataag ctaaagtagc atggatgatt agtataaaaa
     4861 ataaaaccag tttaaaaaac tggtttaatt tgtattcttt gaatttaata tatgtttttt
     4921 catttcctct aataccattg tataggattt acattgagca gcagctaatt ctgataaagc
     4981 aaatttttga gctttattta aaaactcctt atctgtgcta cacaattgtt ttgaactgtc
     5041 ttgtatcata agcattttga ttaattttac aatttcaaaa acatctcctg aatgaaattt
     5101 atcttggtac agtttaagtc tttcttttct atcaaaaatc catacaccat ctgttttatt
     5161 aatagattgg ataaaattat caacatcatt tccatccata actggacgta tgccaattct
     5221 atctgcattt agaactggaa tcgaaatttt aaggttacta ttaaaaatga cacttaattc
     5281 atagtatttt tgcatctcat gatttatttt ctttgttaca atatcattta cagagcaggc
     5341 tccctctttt ggatacatta cactttcacc aattttatac atatgctagt tatacctcca
     5401 aattgaattt tagatattgc aacttaggta caatgcttta attatctaat gattaatatt
     5461 ataacataaa taacttgaca agtcaaaaat attaatatat aatataaagt ttagacttgg
     5521 tgatgtgtga aactaaagag aaaaatataa gataaaataa tttaatatgt tgaaatattc
     5581 ttttacaatt atataaaaat agatactaat tatatttaat aattattagt ttttagcaaa
     5641 atctcttagt ttaagacttc ctgcagttac aaatataatt ccaattaata ttagagctat
     5701 tatatttatt aaaatactac cattgttttt aatagcatct atagtccaat aaaatggtgt
     5761 gaactttgaa agattagtca taaaggataa tttatccatt gatggtatta gactagagat
     5821 agatatagct agacctatta aagaataaaa tgtagatata agacttatag aactttcatt
     5881 tttaaatact ctagctaccc aaaatacaaa tccagtggaa acaaaactat ttgctagtac
     5941 aatcatcaat acattcagac tcaaattaaa gtcttctata attgaaaaac ataatagagc
     6001 aaaagtgtat acaattgatt gaataaaaaa tagtcctaaa aatatactga aaattatttt
     6061 tatatcttta ttatctgtag agataagtct ttttagcaca tttgattttt ttaatgtaaa
     6121 taaatcagaa gcaagatgtg ccgcattaat atacataaaa tagcatatca agaagactac
     6181 taaaaatgaa cctttattct tatctggttt gttatcaatt atatttgtct ttgtcaattt
     6241 atcatctata tttttatcca ctttcaattt taacgattta gtaataaaag attctatttg
     6301 tgattctgcc caaagactac caccaccatt ttcaatttta aagcatttaa ctacaggtcg
     6361 ttgtaattta tctatactat ttgaaaaatt tttatctaaa acgaatacag cagaaacctt
     6421 attatttttt aatagattca tagccttatc ttgttcattt aatctaaatg aattttcttt
     6481 taatttagaa ctatttatta acttatgttc atactttcct gaagagtcag atacaattgc
     6541 tactggagaa aaatacattg attgatttcc cgagttgttg ataaaaaaat taagtgaaaa
     6601 aattagtata ataggaagca taaccatatt aattaaaaga gtatgatttt ttagatatct
     6661 ttttatattt gcaatagtta atctaatcat tattaaacct ccctccattt atatttttcc
     6721 tttacaatag caagtgcaat taatattgta gagataatta aacatgtgaa aattaaatct
     6781 cctattgaat ctatagtttt aaatgtttca taattactaa acaattctcc tattaaatag
     6841 gtaggagata aacttgtaag cttagtaaat gtatcactta tcatactgaa gatacctcca
     6901 aaaattgtct gtaaaaagag taatgcataa actattgctg taccgtattt tttgctaaaa
     6961 aagctggtta caaaggtaga tattgaagtc ataaaataag atgataaagc acaaagtagg
     7021 agcaatatgg caaaattacc tttaaatgtt attccaagta ttctaaagaa taaaacatat
     7081 aataataaga atataaatga ataaatccat aaacctacaa agtcataaat taagaattgt
     7141 actctagtta taggcataga ataaagtctt tttgaaagtc cctttgattc acttatataa
     7201 tttgataaaa tattgttcat tataaaaatt attacaagaa atcctagtga aactaaagca
     7261 aagtattcat aagagctctg tttaacattg ttatttatta tagaagtatc aatagaattt
     7321 ttattaaata atttagaaaa atcttctgaa cttattttct gagaattatt taaataaaat
     7381 ttttcatggt aagtatctaa tatatcttga agcaatattg cgatatcatc acgagttcca
     7441 agtttttcta tgtttagagt atttgatttt tcatttaata aactactctc atagccttta
     7501 ggtatagtaa gctttaattc tgccttagaa tcatcttttt taactgttaa tatataagat
     7561 aaatcatttt tcaaatactt tgtcaaatca tttgataatc ttgtgttatc tttgtcatat
     7621 ataacaatgg gggtagattc tgtttttata gggttttgaa acatgctttc tgtaaccatc
     7681 ccaagaaacc aagataaaat cagaggcaaa gctaaaaaat atattaaatt aagtataaag
     7741 gagcttttta aactctttag catagttttt acactcatgt ataatttcat aaaatcacct
     7801 ccattagtct cttaaatttt ttcctgttag atttaaaaat acgtcttcta ggctaggttc
     7861 ttcataagaa attttcatta tttttgaatt gtttttgtca atgacagaga gtatatctgt
     7921 aagttgtaat tttttatcta tatccaattc taataatgaa ttattttcta aaacagatat
     7981 aacaccttta gtatttttta aatcaaagat aagttgggca tttatatttt ttatttccat
     8041 aattaatttt gtatttgtag atacgagtga ttttaaataa tcattatctc caaaagcaat
     8101 ttctttacct tcatccataa taaaaatttt agaacaaagg tgctcaactt cttccatata
     8161 atgggaagta tatattacag tagtttcatg ttttttagat atatctttta taaaattgaa
     8221 aatatgattt cttgattggg ggtctacacc tacagttggt tcatccaata ttaatatttt
     8281 aggatgattt aagagtgcta ttccaatatt taatctcctt tgcataccac cagataattt
     8341 tttgaccttt ttctttttga cttcagtaag acctgtaact tctaatgctt caatgattct
     8401 ttctttaagt agttttccct ttaaaccgta gaaagctcca aagtactcta agttatcaaa
     8461 aggagtaaga gtttctataa ttgctaattc ttgtggaact aaccctatta tagactttgc
     8521 ttttatataa tcttttgata aatctaaacc actgatttga atactaccac tatttggtaa
     8581 cataagattt gtaattatat ttataagtgt agatttacct gcaccatttg ggccaataag
     8641 tccaaatatc tcaccttttt taacagaaaa gctgatgtta tcaagtacta atttatcatt
     8701 aaatcttttt gttatattat ttactctgac tatatccata gtaatccctc caaaataatt
     8761 ttgtataagt taaaaagcta taatattata ataaagaatt gtgaattata attctattac
     8821 tataagtcac taaaaaaagt gacttaagtc actttatatt tttagattta ttctattaca
     8881 attttatttt tgaaagcaaa gattgctagt tgagttctgt cacgaagttc tagtttagct
     8941 aaaatattag ttatgttatt ctttattgta ccttcagata agaatagttc ttgacttatt
     9001 tctttattat taagtccatt tgcaattagt ctaattatag atatttcttt ttctgttaaa
     9061 ttgtacatgt cataaagatg ctcttgttta accgtttttt cagaggtcat gattttttca
     9121 gctacacttt tatcaagcac aatattgcca aaaaatgaag aacgaatccc ttcatgcaat
     9181 acttcatcag agctatcttt taaaaggtat cctgaagcac caaacttcat agcatctttt
     9241 atatattcat catcattaaa agttgttaaa attaataatg ttatagaatt attatattcc
     9301 tttataagcc ttgtacctag aaccccatca catactttca ttcgtatatc cataagaact
     9361 atgtctacat cattcatttt acaaaattct aaagcttcat atccattaga agcatctcct
     9421 acaatttcta aatcattata agatgataat ataattttaa gaccttttct aattaatttt
     9481 tcgtcatcta ctataagaac tttaatttta ttcaaaaaaa tcaccccctg aaaatttagg
     9541 aaaagaagct ctaattgtga aaccattatt agaattatca aattcaactt taccatttaa
     9601 ttcatatatt ctctcattga tactattaag tccatttcct ttttttatat tgccacatcc
     9661 tataccatta tcactaatag taattataag atttgaagta ttgaatgtaa taaaaattct
     9721 gatttcagtt gcctttccat gcctagatga gttggaaagg gattcctgta taagtctata
     9781 taaagctata gattgatttc tggataagtt ccaagtattt tttgaaatag ttaatttaac
     9841 attaatattt gtaagcttaa taaagctttt aactaattct ttgattttaa ataaactttg
     9901 gtaattttca tattcaacag gttttaactc agatatagcc cttcttacat cttgaaaact
     9961 ttcagttaca aattctctaa gttcatgtac taagtcataa attagaggtt tgtcttttaa
    10021 gagtttttct atagcattta attgtattat tgttgtagaa agagaatgtc ctacactatc
    10081 atgtatttct cttgatattc gatttctttc ttttaaaatt gctaattctt ctatagaact
    10141 tgcataagtt tccaaatcag cattaacttt ttttaattca tctttagaaa ttctaagctt
    10201 atcataaaga ttttgactgt ataattttga taaattctca ttttctatat atatagaaag
    10261 tacagttata attagcaata tagagcttga ctccagtgcc aaatatatat ttttatctaa
    10321 actaataata agagaagata ttataacaaa agagaacaat atgtacttat atttttcctt
    10381 tattaaaaat gatatatcta atattaaagg aacaaagtaa atcgaattaa aagtttttgt
    10441 ataattacaa agtataaaaa ttaatataag ttctaaaaag taagaaataa gtataaattt
    10501 attctcattt gataaagaaa aaaatctaac ttgattattt attataatta gaaataatat
    10561 tatcatagtt atgaccggat acaatgtatt ttcaacattt ttcaaatagc ttacaactaa
    10621 tataaataaa gataaatatc gtataaaagc aactaatttt tctctgttca ttaaaggcac
    10681 tcctccaaaa aaataaactt ttcctatgaa aactagaata atatcataaa agaataaagt
    10741 caatagaagt atttattaat attgatggaa ataaaatcaa tccaaaaact tgaatagtaa
    10801 aattgtatac tgacaataat ttaaaagtga aaatttaatg tattggagtg aataatgaat
    10861 aataaagaaa aaggtgattt tggagaaaaa gtagcagtta attatttgct atcaaaagga
    10921 gcaaagatac tagaaaaaaa ttacagatta aagatagggg aaatagatat aatagcaaaa
    10981 atggaagatg aaattatatt tgtggaggtg aaatcaaggt ctaacataaa gtttggctac
    11041 ccttgtgaat ctgtaagctt caaaaaaaga aaaaagataa ttggagttgc aagttattat
    11101 attataaaaa ataacttaaa taacactccc ataagatttg atgttataga ggtatattta
    11161 ttagaaaaaa gaataaatca cataatgaat gctttttaaa aaagataatg tttttggaaa
    11221 ggattaaata tgttaagtat tattaattca agcaacttag taggaatcga cagcttttta
    11281 gttaaggttg aagtagatgt aagcaatgga atacctagtt ttaatattgt tggtcttcca
    11341 ggcaaagaaa ttaaagaagc aagagaaaga gtaaagtcag caattcttaa tagtggatat
    11401 aaatttccaa gtacgagaat agttgtaaat ttatcaccag cagatataaa aaaagaagga
    11461 gcttttttag atttatctat aagtataggc cttttaagag agttaataaa aaaagatgaa
    11521 aattacataa gagaaagtat gtttatagga gaattatcat tagatgggaa aataagaaaa
    11581 gtaagaggta tattgcccat aattatgggt gcaaaaactc agaacataaa acgtattttt
    11641 ataccaattg agaacataaa agaaagtcta tttgtagatg aaattgatat aattcctatt
    11701 aaaagtttaa aagaatttgt cgatttttta aacgaagaga taaaagtcga taaagtaagg
    11761 ataatgtctt ttttggatga taagtcaaga aaagagaacg aagaattaga aaaagataat
    11821 agttatatag attgcaaata tactaagatt aataatgaag aaagtaaata tgatgaagac
    11881 tttaaagatg taaaaggaaa ttattttgta aagaggagtg cagaaattgc tgctgctgga
    11941 aatcataata tgtttatgat tggacctcca ggctcaggaa aaactatgat tgcaaaaaga
    12001 gtaagaacaa ttttaccaga tataagtgta gaagaaatga tagaagtaag taaggtctat
    12061 agtatattgg gtatgataaa tgaaactaaa ggaataattg ataaaagacc ttttagagca
    12121 cctcatcata caactacaaa gcaatcttta attggaggag gaatggatgc aagacctgga
    12181 gaaattgctt tagcacatag aggtatctta tttttagatg agatagccga atttgataga
    12241 aaaatacttg agactttaag acaacctata gaagatggat atgtaaatat atccagagta
    12301 aagtacagtg caaaatatcc ttgtagagta ctgttagttg cagctatgaa tccatgtcca
    12361 tgtggttatt atatgtcaga gacagagtgt agatgtagaa gtaacgaaat tgatagatac
    12421 ataaataaaa tatcaggtcc attgttagat aggtttgata tttttgtaga agttaattct
    12481 ataaaatatt cagattttaa ttctttaaaa caagaagaaa gctctcaaaa aataaagaga
    12541 agagtagaaa atgctagaaa aatacagata aatagattta agaaggataa tataaaaaat
    12601 aatagtgaaa ttaaagctta caatttattt aaatattgta aactggaaaa agaagcttca
    12661 aaaacggctg agatgatatt taataaatac aacctaagca gtagaagtta tacaaaactt
    12721 ttaaaaatgg caagaacaat agcagattta gaagaaagag acttgataaa ttcacagtgt
    12781 attatagaag ctttttcatt tagaaaggct tattatagtt attttaaata gttttttgag
    12841 gtggatttta tggaaaaaag agatacttat ttatggttaa aatcaattgg tggaataaca
    12901 acaaaaacaa ttgaaataat agaaaatgaa atagtaaata ttgaagatat atttgatttt
    12961 tctgaaaaag aaatatataa tttaaaaaat ataagcttga atattagaaa aaatatagta
    13021 aaatatagag gtcacgctta tttagaaaat ataaaagaac tactttacaa aaaagcgatt
    13081 aaatatattt gtaaatatga taaagaatat cctgaaaatt taaagaatat atacaacgct
    13141 ccaaagttat tattctacag aggtgacata ggtttagtta ataataattt taatatagct
    13201 atagtaggtt caagaaaacc tacagcctat ggaattaatt gtgcaaaaac aataagttgt
    13261 caactatccc aatatggagt taatatagta agtggattag ctataggaat agatgcatac
    13321 tcgcacatag gttgtatgag tggaaaatct aaaactatag cagtacttgg ttcaggagta
    13381 gacaatcctc ttccaaaaca aaatttacat ttatcaaata aaatattaga aaatggggga
    13441 ttattattat cagagtataa tattaactcg acagtagccc cgtaccattt ttctaataga
    13501 aatagaatta tcagtggttt aagtgatgga gtagttgttg tagaagcagc aataaaaagt
    13561 ggtgcactaa tcacagtaga ttttgctctt gaacatggaa aaaatgtttt tgcaatacct
    13621 ggtaatataa attctcaaat gagtagaggt tgtcataaaa ttataaaaga aggtgcaaaa
    13681 ttaattgaaa atatagatga tattttaaat gaatataaca tatttaatat tattgataaa
    13741 aaaataaatc aaaaatatga taatataagt ctaaatgcca agtctaagca aataattgaa
    13801 gctataaaaa gagaaggaaa cttgcatata gatagtattt gtgattatac tggtatagaa
    13861 ataaagtatg taaattcaat aatcaatgaa ttagtactaa atgagttagt agtagaaatg
    13921 aataataaaa cgtacagttt aaatgtataa attaagatta ggtagtgggg gtgtatggtt
    13981 ttatggccaa aacattagtc atcgtagaat cgcctgcaaa agctaaaact atagaaaaat
    14041 ttttagggaa aagtcattac acagttaaag catcagttgg tcatgtcaga gatttaccta
    14101 aaagtaaatt aggtgtagat atagaaaata attttgaacc tcaatatata aatataagag
    14161 gaaaaggcga tgtaataaaa gaattaaaaa aagaagctaa aaaatctaaa caagtatatc
    14221 tagcaactga ccctgataga gaaggtgaag ctatatcatg gcatttagct catatactaa
    14281 atttagatga atctgaggat tgtagaatag agtttaatga gataactaag gatgcaatta
    14341 aaaaagcaat taaacatcct agaaatattg atataaattt ggttgatgca caacaggcaa
    14401 gaagagtgct agacagactt ttaggttatc aaataagtcc tatattatgg caaaaggtta
    14461 gaaaaggtct tagtgcaggt agagtgcaat ctgttacaac aaagttaatt tgtgatagag
    14521 aaaaagaaat aaaggcattt attccaaaag aatactggac aatagatgtt gaggctaaga
    14581 cagtaaaaga caaagatata actttgaaat tttatggtaa aaatgatgaa aagattgaat
    14641 tagaaaatga agaagctgta aatgaaatac taaaagaaat ggaaggtaaa gatttaaagg
    14701 ttgagaagat agaatctaaa tcaagacgta aatcagctcc aaaaccattt acaacaagta
    14761 tgcttcaaca agaaggagca aataagttat tttttactac taaaaaaaca atgatgatag
    14821 cacaagaatt atatgaaggt atcgacatag aaggtgaagg tactgttggt cttatatcat
    14881 atataagaac tgactctaaa agaatatctg atgaagcaaa agaaaaagct aagggctata
    14941 tcgtaaacaa tttaggagaa aactactata aaaacactgg tgataaaaaa gaaaaaaagg
    15001 atactaaaaa ggttcaagat gcccatgagg caataagacc aacctcagtt gatagaactc
    15061 ctgagagtat aaaagcctca ttgagcaaag accagtacaa gttatacaat ttaatttgga
    15121 gaagatttgt agctagtcaa atggaagatt cagtgtttga tatactaaat gtagaatgta
    15181 aaataggcga tattgtattt aaggcaactg gttcaaaaat gaaatttgat ggttatacca
    15241 aggtatataa tttttcagaa agagaagaca aaattttacc aagtatagaa aaaggagata
    15301 tattaaatat agaaaatata ttgccagacc aacattttac acaaccacca gcaagatata
    15361 cagaagctag tttagtaaaa acactagaag aactaggtat aggtagacca agtacgtatg
    15421 ctccaacaat agctactata ctgaatagag agtatgttga aaagcaagga acaagtctat
    15481 gtccaacaga acttggaata atagttactg atattttgga aaataatttc cataaattta
    15541 tagatgtaga ttttactgct gatatggaaa gtaaacttga tgttatagaa gaaggcaata
    15601 cagattggaa aaagattgta tcagaatcat atgcaccact taaagaggct attgaagaag
    15661 ctcttgaaaa tatagaaaaa gtaaatatgg atgaagaaac tgatgagatt tgcgagaact
    15721 gtgggtctaa tatggttatc aaatatggta aatttggaaa gtttatggct tgtaaaaact
    15781 atcccgattg taaaacaact agaccaatta tgaataaaat tggtgttaaa tgtccaaaat
    15841 gtgaagaagg agatattata cttagaaaat ctaaaagagg taaagctttt tatgggtgtt
    15901 ctaattatcc aaactgtgac tttgtagctt ggaataagcc aacaggagag ttttgtgaga
    15961 agtgtggttc atatatggtt gaaaaagtga ctaaatctga aacaaaaaca gtgtgttcta
    16021 ataaagaatg taataaagag acaaaagagc ataatgacgg aaaagagtga aaattgaaaa
    16081 aaatcacata attctcttga aaaaggttcc aatctatgat aatctttcaa gtgtaaacaa
    16141 ctaatagaaa aataaatttt cattaaatgt gaaaataata ttagaaaata taaaaggtta
    16201 ttaaaaggcc taaatttcat gaggagatga ttaaatggca agtgaagtgt tacaaaaaac
    16261 aaggaaaata aataaaacat tacaaacaag tggtggaagc agtgtctctt ttgatttact
    16321 ggccggagca ttgggcgacg ttttaagttc taatgtttat gtagtaagtg caaaaggtaa
    16381 agtactaggt cttcatttaa atgatgttca agacagttca gttatagaag atgagtatac
    16441 taagcaaaag aaattttcag atgaatatac tcaaaatgtg ttaaaaattg atgaaacatt
    16501 agaaaattta aatggtgaga agatattaga aatctttcct gaagaacatg gaagattaca
    16561 aaaatatact acagtagttc caatattagg aagcggtcaa agattaggaa cattggtact
    16621 ttcaagatat tcaaattcat tcaatgatga tgatttagta atagctgaat acagtgcaac
    16681 tgttgttggt cttgaaatat taagagcaat aggtgaagaa ttagaagaag aaatgagaaa
    16741 gaaagctgta gttcaaatgg caataggcac tctgtcctac tccgagcttg aagcagttga
    16801 acatattttt gctgaattgg atggaaaaga aggtttactt gtagcaagta agatagctga
    16861 tagagttggt ataactaggt ctgtaatagt aaatgcactt agaaaatttg agagtgcagg
    16921 tgtgatagaa tcaagatcat taggtatgaa aggtactcat ataagaatac ttaatgacaa
    16981 acttacagat gaattaaaaa aattaaaaaa caatcaataa tctatatttt ataggtttag
    17041 attagaaaag gtatctattt caaatagata ccttttttag acgaattatt aaggtaatga
    17101 taagtatatt aaaaaggagt gagaaaatgc ctttagcaga taaaataaga ccaaaaacaa
    17161 tgaatgatgt aataggtcaa agtcatataa taggtaatgg aaaaatattg tctaagatat
    17221 tacaatctaa ttttttacca aatatgatat tttttggtcc tcctggtgtt ggtaaaacta
    17281 cagtagcgga aataatagca gaaagaagca ataaaagctt ctataaaata aatgctacta
    17341 attcatcttt agaagatata aaaaaggtga tatcagagct tggaagtata aataatgtaa
    17401 atggagtcct attatatata gatgaaatac aaagttttaa taaaaaacag caacaatcaa
    17461 tattagaatt tatggaaaat gggagtataa ctttgattgc tagcactaca gaaaatccat
    17521 atcattatgt atataaagct cttttaagta ggtctactgt atttgaattt aaacctttag
    17581 aaaaacttga tatagaaaaa ggactgaaaa gagctgttga agtattaaat gaagatagct
    17641 atatggatat tgagtgcaat aataatgcta ttgaagatat agcaattctt tctgatggag
    17701 atatgagaag agccttaaat attttagaag tggtagtcta ttcaactaaa ccaaataagg
    17761 ataatataac ttatatagat tcagatgtaa taagggcatc tacatttaat aaaattataa
    17821 actatgacaa aaatggtgat agtcattatg atattttaag tgcatttcaa aaatctataa
    17881 gaggaagtga cccacaggca tctatacact atctagcaag acttataaaa ggtggggatt
    17941 tgataagtat atgtaggaga cttttagtaa tagctagtga agatataggt ttagcttatc
    18001 caaatgctat tgtaattgta aaggcatgtg tagactcagc tatgcaactt ggatttccag
    18061 aagcgaaaat accattagca gaagctacta ttcttttggc tacatctcca aagtctaatt
    18121 ctgcatgtat agcaataatg aaagctatgg atgaactgga taaagagttt gttaaggata
    18181 taccaaatag tataaaggat gctcactatt ctggttctaa agaaataggt aggggttgtg
    18241 gatacaaata tcctcataat tttaaaaatc attatgtaaa gcaacagtat ttaccagata
    18301 gcataaaaga tagtatttat tacataccac aagaaaataa aactgagaaa aatataaaaa
    18361 aatatttaga atatctaaat agtgattttt agactgaact ttatgtatcg ggggtagata
    18421 ttatgattat aaaacttaac tcaacttatc acagtagagt tatgaaatac ttaaaaaaag
    18481 aacctgagta caatttgttt ataatagggg atattgaaag atatggatat ggaaataatt
    18541 ttttaaatat atgggcagat gtgggtgaac atggtgaaat aaaggcaata ttacttaaat
    18601 attttgaatt tatgatgttt tattctgatg gagagtatga tgttgaaggt ttttataatc
    18661 tacttcgtaa tactaattac gaagaaatat ctgggaaaat atgtgctgta gatgctttag
    18721 caaagagatt aggacttaat aatttaaagg tagttgattt ttgcaaactt caaactaaaa
    18781 agtttttgat agataataac tgtaatgcaa aggttaagag aattaggctt ggaaatctaa
    18841 aaaagacagt gaaactttat gacttaatag atgaatttca cagtacaact ttagagaatt
    18901 taaaaaatgg actaaggaca ggtagaggat attgtataga gattaacaaa caggtggtgt
    18961 caatggcaaa gagtacttca gaaaatagga ctcatgcaat gataattgga gtaggaacac
    19021 atcctaaata tagagctaaa ggacttgcta caaaatgcct aattaaacta tgttcagagt
    19081 tactgagaga aaacaaaatt ccttgtttgt tttatgataa tgaagaggct ggaaagatat
    19141 ataaaaaact aggatttgaa aacattggaa aatggggaat ttattcaaaa taaaaaatta
    19201 aaattaatct tgacaaaatt agtagggtat aataaaatta tcttgaaagt aattcctact
    19261 aaaacagtat gaattagatt tctatataga ggtgataata tatgaagttg tctactaaag
    19321 gtagatatgg actaaaagca atgtttgaat tagcattaaa tcaagacaat ggaccagtat
    19381 cattaaaatt tattgctaag aagcaaaaaa tatcagatca gtacttagaa caaatatttt
    19441 catctttaaa aaaatcgggt ctagtaaaaa gtgtgagagg tgctcaagga ggttatttgc
    19501 tttcaaagaa tgctgaagac ataacagtag gagatatact tgtagtatta gaaggaccag
    19561 ttgcattatc tgactgtgta ctagatgaag atgtatgtga aaactcaaac atgtgtgtaa
    19621 caaaaatagt ttgggaaaag atgaaaaagg gtatagaaga tgttatagat tcaattactc
    19681 ttaaagatat gataaatgac tataacaaaa ataaattaga aaatgatata acaaatatta
    19741 aaaaatagat ttggagatga atgtaatgga aaaaagaaga ttgtatatgg attattctgc
    19801 aacaacacct attaaaaaag aagtattgga tgcaatgatg ccatacctaa cagattattt
    19861 tggtaatgca tctagttttc acacattcgg aagagaagca aaagatgctt tggataaagc
    19921 aagagaacaa gtagcagccc ttataaatgc tgaacctagt gaaatatatt ttacagcagg
    19981 tggttcagaa agtgataact ggacactaga gggtgtagct tatgctaata aaaacaaagg
    20041 taatcatata ataacttcaa aaatagagca ccatgcaata cttcatacat gtgaatactt
    20101 agcaaaacat catggatttg aaataactta tttagatgtt gatagcgaag gaaaagtaga
    20161 cttaaagcaa ctagaagatt caataaaaga tactactata cttataagca taatgtttgc
    20221 aaataatgaa ataggaacta tacagcctat taaagaaata tccgaaatag ctaaaaaaca
    20281 taagatatta ttccacactg atgcagtaca agctacaggt aatattccag tagatgttaa
    20341 agaattagga atagatttga tgagtatgtc ttcacataaa atatatggac caaaaggtgt
    20401 aggagcttta tacataagaa aaggtgtaag acttcataac tttgtccatg gtggagcaca
    20461 agaaaaaagc aaaagagctg gtacagaaaa tatacctgca atagttggat atggaaaagc
    20521 agcagaatta gctaaggaaa atatgcaaaa tcatgtagaa actttaactc gtcttagaaa
    20581 taagttaata gatggtgtgt tagaaagaat accttacaca agagtaaatg gtagcttaga
    20641 aaatagattg ccaggaaatg caaactttgc attccaattt atagaaggtg aaggaatact
    20701 tttattatta gatatgttag gaattgctgg ttcaagtggt tctgcatgta cttctggttc
    20761 attagaccct tcacatgtac ttcttgcaat aggtttacca catgaaatag cacatggttc
    20821 attaagactt acagttggag attttacaac agatgatgat atagattata tactagagaa
    20881 cttaccaaaa gtaatagaaa gacttagaag catgtcacca ctttatgatg atgcgaagaa
    20941 acaaggttta gtaaaataga cataaagata aagcataaaa aatagacata aattgagtag
    21001 gaggaaaaga taatgcaata tagtgataaa gttatggaac attttatgaa tccaagaaat
    21061 atgggagaaa ttgataatgc aagtggtgta ggtgaagttg gaaaccctac atgtggagat
    21121 ataatgaaga tatttttaga catagatgga gatgtaataa aggatgttaa gtttaaaaca
    21181 tttggctgtg gttcagctat agcaagttct tctatggcaa ctgaaatgat aaaaggaaaa
    21241 actataaaag atgcattaga acttacaaat aaagctgttg cagaagcttt ggatggttta
    21301 ccaccagtaa agatgcattg ttcagtttta gctgaacaag ctgtaaaagc agctcttata
    21361 gattatgctc aaaagaacaa tatccatata ccagaattgg atggatatgt tatagatgat
    21421 gctcatgacc atgatgttga agaagaagaa taaaaataag tgattgtgtt atgagaagtt
    21481 tacaatgatt aaaaagaagt actaatgata taattaggac ataaaaaata gctgttttta
    21541 aaatggctat tttttattgc ctaaattaag tattttaact tgatttagag gttaattagt
    21601 taacaaaata atccataaga ttcaaataat aaagatgatt atttttttag aaaatagaac
    21661 aagctatatt ttaaataagt acaatacttg ctctatatgg tataataata agtaatgcaa
    21721 aagatgaggt gaaatttgtt tatgaataaa aaagtaatga taggtatgag tggaggagtt
    21781 gatagctctg tagctgcata tcttttaaaa caacaaggat atgatgtcat tggtgttact
    21841 atgaagttgt ggcaagatga tgatgttgtt gaaattgaag gtggttgttg ttctttatct
    21901 gctgttgaag atgctagaag ggtagcaaat aaaataggta taccatttta tgttttaaat
    21961 tttagagaag tgtttaaaga aaaagtaata gattatttta tagatgaata tttggaagga
    22021 aaaactccta atccctgtat agcttgtaat aaacatataa aatttgatga tttttataag
    22081 aaggctagac aaataggttg tgattatgta gctacaggtc actatgcaaa gatagaaaag
    22141 gatgaaagta caggaagata tttgctaaaa aaatctgtta cagataaaaa agaccaaact
    22201 tatgcacttt ataatcttac acaagagcaa ctagagcata ctttactacc aataggtgac
    22261 tatgaaaaag atagagtaag agaaattgct aaggaaatgg gtatggcagt acacaataag
    22321 cctgatagtc aagaaatttg ttttgttaaa gataatgact atgcaaatta tgtaaaaaaa
    22381 cattctaaaa agcgtattga agaaggtttt tttgtagata ctaaaggcaa tatacttgga
    22441 aaacataagg gtatattata ttatactata ggccaaagaa aagggcttgg aattactttt
    22501 ggaaaaccaa tgtttgtaat agacataaat ccaataaata ataccatagt tcttggagac
    22561 aatgaagatt tatttaaaaa ggaacttatt gctaaagatg ttaattttat atcaatagat
    22621 acgttagaag aacccttaag agttcaagcc aaaataagat attcagcaaa accatcacca
    22681 gctactattc atagagtagg agaagatact attaaaatag tttttgatga agctcaaaga
    22741 gctattacta aaggtcaatc tgtagtaatg tatgatggag atattgtagt aggtggaggt
    22801 ataatcgaga aaagtttata aaaacatcta aaaaattaaa aaaataagca ataaagtata
    22861 ttaagagtaa ataaagttta taaaataaat ttattgtata tgaaaatata gtattgatta
    22921 attttgtaaa atttagtaat ataattagta tattaattaa aaaacaaata cagtgataag
    22981 gaatagtaaa atatttgatg tcttacagag agagggaaat gctggaagcc cttagaatat
    23041 gatatttgaa gcagcctttt agtagcaatc ttgaacaatt tatattttat aaagaagatt
    23101 taagtagaga ttgacggtag ttacgttata gctaaggttt tccgaagata tcatactttg
    23161 tatgataatt agggtggtac cgcgattgtc ctcgccccta taaatttatt tatagggacg
    23221 aggtttttta tttaaacgaa aaaataaaat ttattaggag gaacatgata tggaaaagat
    23281 gggattaaat gaaataagaa gtaagttttt agaatttttt gagtcaaaag gtcattatgt
    23341 agcaaatagt tattctttag taccaaacaa tgataagagt ttgttactta taaactcagg
    23401 tatggcacct ttgaaaaact acttttcagg tgtagaagta cctccaagtg tgagaatgtg
    23461 tacatctcaa aaatgtataa gaacaggaga tatagaaaat gtaggtataa ctgcaagaca
    23521 tgctacattc tttgaaatga tgggtaactt ctcatttgga gattacttta aaagagagtc
    23581 aatcaaatgg ggatgggaat ttgttacaga atggctaaat ataccagaag ataagatatg
    23641 ggtgactgta tatgaagaag atgatgattc ttatgatata tgggcaaaag aaatgaattt
    23701 cccagaagaa agaatggtta gacttggaaa agatgataat ttctgggaaa taggtacagg
    23761 tccttgtggt ccttgttcag aaatatattt tgatagagga gaagaatatg gatgtgacaa
    23821 tccagactgt aaaccaggct gtgattgtga taggtattta gaattttgga accatgtatt
    23881 tactcaattt gatagagatg aagaaggaaa ttatagtcta ttagaaaaca agaatataga
    23941 tacaggtatg ggtcttgaaa gaatgggttg tattatgcaa ggcgtagaca ctatctttga
    24001 agttgataca attaaatcta tactagaagc agttgagaag ttaacaggag taaaatatgg
    24061 agagaatcca aaaaatgata tatcaataag aataataact gaccatataa gagctgtaac
    24121 attcttagtt agtgatggag tgcttccatc aaatgaagga agaggatatg ttcttagaag
    24181 actccttaga cgtgctgctc gtcatggtaa gttattagga gtaaaagaat tatttttaca
    24241 gaaactaata gatgaagtta taaaagtaaa tgataaagca tatccagttt tagttgaaaa
    24301 agaaagttat attaaaaaag tagttggaat agaagaagaa aaattcaatg aaactataga
    24361 ccaaggaaca gaaatattga actcttatat agaagtatta aaaaatgaag gaaagactgt
    24421 cctaagtggt caagaagctt ttaaactata tgatacttat ggcttcccta tagacttaac
    24481 taaagaaata ttagaagaag aacatctatc tgtagatgaa gaagctttta atgaagaaat
    24541 ggaaaagcaa aaagaaagag ctagaaatgc tagaggaaat atggatggag aaagttggaa
    24601 ggaagaccct ctatcaaaat tagaatctac agttgacagt acatttaatg ggtatagtga
    24661 aatttatggt gaaggaacta ttgaagctat agttaaagat gatgagctag ttcaaagtgc
    24721 agaagaaggc gataaggtat ctatagtact agataacact actttctatc ctgaaggtgg
    24781 aggacaagtt ggagattgtg gattgataac taatgaaaac ttagttttag aagtattaaa
    24841 tactaaaaaa ggtgctaata atagtataaa acatataggt ataataaaat caggaagaat
    24901 aagtaatggg gacaaagtaa agacactcgt agatagagaa actagaatgt cagctgcaag
    24961 aaatcacagt gctacacatt tacttcataa ggcattaaga gaagtattag gagaacatgt
    25021 taatcaagct ggttctttag taactccaga aagacttaga tttgatatta ctcactttga
    25081 agcgatatca aatgaagaat taaaagtaat agaagaaaaa gtaaataatg ttattttatc
    25141 atctttagac ataaaatgtg atattatgaa tataaaggaa gctaaagaaa aaggagctac
    25201 agcactattt ggtgaaaaat atggtgatga ggtaagagta gtttctatgg gagattattc
    25261 tacagaactt tgtggaggaa ctcacttgac aaatacttct caagtaggaa tgttcaaaat
    25321 attatctgaa ggtggagtag cagcaggtgt aagaagaata gaagcaataa caggaaaagc
    25381 tgtttatgaa tacctaaaag aaagagatgg aattatctct gaagtttgtg taaacttaaa
    25441 atctaaagaa gataatttaa ttcaaagaat aagttcttta ttagaagaaa ataaaaactt
    25501 atctaaagaa ttgcatgata tgaaagctaa gatgagttta caatcagttg attctatttt
    25561 tgattctaaa gttgaagtaa atggagttaa tttgataact aataaatttg aaggtatgga
    25621 tatggataca ctaagagaaa cagcagataa tctaagagat aagcttggtt ctggtgtagt
    25681 agtacttgca aatgtagtag atgataaagt taactttgta gttactgcca ctaaagatgt
    25741 attagataag ggaatacatt caggtaatat tgttagagaa gttgcaaaaa tagctggagg
    25801 aaaaggtgga ggaagaccta atatggcaca agcaggagct agtgatgtat ctaaggttga
    25861 ccaagcttta agctatgcaa gtgaggttat taagacacaa gttaaataac attcactcaa
    25921 ggaggttttt agtttggaaa aagatttaga ctacactatg aaatttgaag gaataccaga
    25981 agataggatg agtgtaggag atactattga ttttgtatat aaagcattag ttgaaaaagg
    26041 atataaccct ataaatcaaa ttatagggta tctcctttct ggtgattcta gctatataac
    26101 tagtcataaa aatgcaagag ctataattaa aaaatttgaa agagatgaga tacttgaaga
    26161 agtaatcacg cactatctga atagaaagta ggtcaaataa atgagaaaaa agattatgtc
    26221 gttgtttgca atagtcatta tgatttttgt atcaactgct agctatggtt ttgctgaaga
    26281 aaaaggcaag gtcatattta ttgatatgaa taggaccaat cttggaagta tgatgaatat
    26341 tccaatcttg aaaaatgaga tagaaaagag aggctatgta gctctcatga atataagagg
    26401 ggatcaaggt actgatgata gaaggtctta tgcaagtatg ggtgcaggaa caagagctag
    26461 tgtaactact gaagactata tcaattttca aaaagtagac caagatactg ctaaagcttt
    26521 tgaagtcgca acaggtcaaa aagctaaaga aataaatgat ttaggcatta atagatctat
    26581 aaatgaaaat cttgagtatg gagaatatgg agcaaattta gggtcattag gaaaaacttt
    26641 atcagaaaat ggtttaaaga catctgtaat tggaaatgct gatataattg aaaataatca
    26701 attagttaaa aacagaaact tatgtttagt agctatggac caatatggaa ggattgattc
    26761 aggtaatatt gataatatta ataagaaaga ttctaaaatg ccatttggaa tatctacaga
    26821 ttatgataaa ttactagatg aaactaaaaa atcctataaa aatagtgatg ctatatttgt
    26881 agaacttgga gatacatata gattagatat gtatagatta aatctaaatg ataatactta
    26941 tgatacaatg aagaaaaata ttgtaaaaaa tataaataaa tatcttgaac aagtattttc
    27001 tatggttgga gaaaatgaca ctgtttatat agcaagtgca tttccaagtg acctagatta
    27061 taagaataag agaagacttt ctccaataat aaaatttagt ggagaaggga aaggtctact
    27121 ggaatctgcc acaacaagaa aggctggaat tgttgccaat ttagatgttg gagtagatat
    27181 actaggtaca tttggtcttg aaaataaaga gatggtaggt agaagttata ctttagtaaa
    27241 taaagaggac aatattagct atctaaaatc actttatgaa aggatagtgt ctatatcttc
    27301 aataaggtca actattataa atggctttgt aggcgtaata tctgcttctt gggtaattgc
    27361 catgtttgcg attttcttta gaaattatat gccacataaa gagcgtgtat tcaaagtact
    27421 taaggagttt ataaaattag gcataataat gccactatca tttatgttag ctcctttgat
    27481 gaattttaaa actccaattt caatatcttt gggaatattt gcaactacgc taatattata
    27541 cttgttaggt agaaaattat ttaaggacaa tgatataaag cacatgggat tttttgcaac
    27601 acttactatt ttagtcatag ttatagattc tgtatttgga acatacttaa tgcaaaataa
    27661 cataatgagt tatgatgctg tcataggagc taggtactat ggtgtaggaa atgaatatga
    27721 aggtgtaact atagcaagtg cagtatttgg cttagcagta ttattacatt ataagaaggt
    27781 atctaaatta cttgttgtaa ttttttcatt aataatactt ataactagtg catatccttc
    27841 aatgggtgca aatgttggtg gagctatatc agaatgtgta gcatatttgt tgtttataat
    27901 gcttatatat gacattaaaa tagattttaa gaaagctgta ttattagctg tttcagctgt
    27961 agttgtcgtt tttgcatttg cagctttaga tatactttca ggtagtgaat ctcatttagg
    28021 tatgtttgta cagagaattt tcctaaatgg accaggagag atattacaaa catttggaag
    28081 aaaaattcaa atgaatatgc aactagcaca gacaagtgta tgggtaaata ttttacttgt
    28141 aggaattgga gtaattgcag tgcttatatt taaaccatct agacacttta gaaagataat
    28201 gaataatttt ccaatcttgt ttaaagggtt tattgcatct atggttggtt gtataattac
    28261 acttttagtt aatgattctg gaatagttgc tgcatctaca gcatctatat atatacttat
    28321 accactaata ataataagta taaatatgat aatatttgaa aaaaataact aaaaaaattt
    28381 ttactgttca tataggattt aaataaaaaa tgcaatatga ttattaatgt aaactggatg
    28441 cttacataaa aaatcatatt gcaattttta tgattgatta tgtaaaatta tatgaagcag
    28501 taagcctgtg accttagtta tgagaggttc agaatatgta tttaatctat agaatataaa
    28561 tagataaagg aggaactatg ttagatggaa gaataatggg tcttgatgtt ggtgataaaa
    28621 ctattggagt tgctgtgagt gatttgatgg gattaactgc acaaggtgta aaaacaataa
    28681 aaagagttgg caagaaaaaa gatattgaag agctaaaagc aataataaaa gaaaaacaag
    28741 taaataaaat tgtatcagga ttaccaaaaa atatgaatgg aactttaggt ccacaaggag
    28801 aaaaagtaat caagttttgt gaattggtaa aagcagaaac aggtattgat gtagagtttt
    28861 gggatgagag gctttctaca gtagcggcag agaggtcttt attagaagca gatgttagta
    28921 gacaaaaaag aaaaaaggtt atagatatgt tggcagcagt aataattttg caaggatatt
    28981 tagattttaa aataaattca taaaagaact ataaaattga atacttatga tatataatat
    29041 aaataataaa aataaaaata aatttgaggt gaatgacatt atggaagaaa atataataaa
    29101 tttaatagac gaaaatggcg ttgaaagcca atttgaaata atattaacat tagaagcaga
    29161 aggaaaagag tatgcaatat taatgccttt agatgatgaa gaagctgaag aagctttaat
    29221 ctttagaatt gatgaggatg aagaaggtga aatcttaata cctttggaaa gtgatgaaga
    29281 gtatgaaact gttgtagctg tgtatactgc tataatggaa gaagaaggtt taaattacga
    29341 cgaagatgaa tcaaatggac ttaactagat aagtaattaa gtttgtatat aaaaatcaga
    29401 tatttattat atttgcttta attaaacctt attaattgta aaagcattta tagtatatat
    29461 ctgttttttt gttttttatt aaaaatacca aaaaatttat gaattttggt gaataatata
    29521 tcttttatgg gtatatattt atattatgag aataaattaa atttatttaa atgtcttgac
    29581 aaaaaatgaa ttatcaatta caatattatt taataaagat tatcaattga aaatagtaag
    29641 ggtgatgtta tggcaaatac aatggattta ttaaaagaca agttaaaaga aactggtttt
    29701 aagattacgc cacaaagaag agcaatagtt gaaatattgc ttaaacatga ccattcacat
    29761 ctaagtagtg aggaaatcta tgatttagtt agggttgact gtcctgaaat aggcttagct
    29821 actgtatata gaacaatgca gctattggat gaaataggat taatatcaaa actaaactta
    29881 gacgatggat gtataagata tgagattagt ctacataaag aagactgtca taatcatcat
    29941 catcttattt gtaaaaattg tggaaagata atggaagcta aagaagacct tttagacaat
    30001 atagaaaaag agatacaatc attgtacaaa tttaaaatac ttgatcatga tgttaaattt
    30061 tatggactat gtgacgagtg taatggagta agcgattcag aagaataaac ttctattgct
    30121 taatgtcgat ggaagaatag tatagaactt ttatattcta tgctattctt ccatttttta
    30181 ttataaacca tctataaaat gcaaatatac agttttcaag atgcttatag ttttaatatt
    30241 gaaaatataa ttaatcctat aagtacaaaa atgaatgatt tttctatgaa attactaaat
    30301 ggtcctccaa cagttaaaaa acctaaagaa attttctttt cgcttagcgg ataaaaaatt
    30361 ggtattcctt gctttgtaaa taaatctcct aaaaacatat gacttgcata accaatcgta
    30421 ccataaaaag ataaattatt aatattagtg attaattcta tctgttttag taaaaaatat
    30481 actattatag ttgcaaatat gctatgagaa aaacttctgt gctttaacca gggaaaaatt
    30541 gacaacatta gacaaaaaat tgtaaaatat atttcaactt ctatgatgta taagcatata
    30601 gctaatagta taaatattaa tgatagaaaa acttttctta gaaatgtgtg ggttagtttt
    30661 gcttcaataa ttataattgc aacaaatgta attattgcgc ttaaataaaa attatcattt
    30721 atatttattg aaataaagaa aataataata ttaacagcat atataaaaat tctatatatg
    30781 tatttggata cattgttttt tagaatgaaa tttgagacca tagaattaga tttatccaaa
    30841 tcgggtagta cagcaaaagt agctgaaact aaaatatcaa ctaaagatat aggaatttta
    30901 aatattaaag atgtttggat agctgttaag attcctattg cacaatgagt tttaccacgc
    30961 ataaatcctc ctaaattatc cgatattaaa tcatataata tttagaggat atcaaaataa
    31021 aataggtttg tcaaaataat acgttaaatg tattttaaat atagcttaaa atatgatacg
    31081 aattatggta caataagaat aactggtagc gagtgcgtga tttgatatta tttatgattg
    31141 tagaacgtgt taaaaaatta aatagacaga aggagatgat gcaattgttc aaaaagaaca
    31201 ccaacaagat aaaggtaatg gccttgggtg gacttaacga agttggaaaa aatatgactg
    31261 ttgttgagta taaagatgaa ataattgtta tagatgctgg acttagtttt ccagaggatg
    31321 aaatgttagg agtagatata gttataccag atataactta tttagtaaaa aatagggata
    31381 aaataaaggg tatatttatt acacatggac atgaagacca tataggagct cttccatata
    31441 tattaaagaa aataaatgta cctgtatatg gggcaagact tagtataggt cttatacaag
    31501 taaaacttaa agaacataaa atgaataatg ttaagttaaa tgttataggt cctagacaag
    31561 ttataaagct tgataatatg gaagtagagt ttttgaaaaa taaccatagt ataccagatg
    31621 cttactctat tgcaatacac acagaccaag gtataatata ccacacagga gattttaaga
    31681 ttgacttgac tcctattgat ggagatgtta tggatatgca tagaatctgt gagttgagca
    31741 aaaaaggagt tcttttaatg ctggcagata gtactaatgc agaaaaacca ggatttacta
    31801 tgtctgaaaa gactgttggg gtaggtcttg acgaattatt tgcaaaagga aatggcagaa
    31861 gaattatagt tgctaccttt gcatccaaca tacacagatt acaacaaata ataaatactg
    31921 ctgaaaagtt taatagaaaa gttgctatat caggtcgctc aatggtcaat gtagttggag
    31981 ttgcaaaaga attaggatac ctagatattt ctgatgacat gcttatagat ttaaatgata
    32041 tatgtaagta tgaagatagt gaattagtga taataacaac tggttcacaa ggtgaaccta
    32101 tgtcagctct tgctagaatg gctttttcag agcacaaaaa agtagaaata aagagtggcg
    32161 atttagttat aatatctgct catccaatac caggaaatga aaaattaata tcaagagtaa
    32221 tcaatttctt atttgaaaaa ggagcagaag tagtatacag tgatatagct gatatacacg
    32281 tttctggaca tgcctgtcaa gaagaattaa aacttataca tgcattagtt agaccaaagt
    32341 tttttatgcc agctcatggt gaatatagaa tgttaaaaag acatgctgaa atagctgaac
    32401 agcttggtat ggataaagaa aatatttttg tcatgcaaac aggagatgtt ttagaattag
    32461 ataaaaattc tgctaaggta gcaaaccgta tacaaacagg aaacatatta gttgatggtc
    32521 taggagtagg cgatgtaggt aatatagttt taagggatag aaagcattta tcagaagatg
    32581 gtcttatgat agttgtagtt actatttcca aggatgaggg taaggtctta gcaggtccag
    32641 atataatttc cagaggattc gtatatgtaa gagagtcaga agatttaatg gatggagcaa
    32701 aggatataat taagaatgtt ctaaatgaat gtgaagagaa aaatattaaa gaatgggctt
    32761 atttaaagaa taatattaaa gaaaacctaa aagaatattt atatcaaaaa actaaacgaa
    32821 atccaatgat acttcctatc ataatggaag tataatataa aaaaactata aatttgaaaa
    32881 ttagacctct tgtaattttt aaagtaatat caaaaatcca attgatatta tcttaagaat
    32941 tacaagaggt ctttttaata ctcattttaa aaaatatata tattacataa aataccaatt
    33001 ataacaatct tttattagta aaaactactt atatataaat tttactgata ggaggattct
    33061 tatggatgat gtttcaagac aaaatgctat aaaagcttta aaacaaacaa aaatggaaat
    33121 agcaggagag tatggaatga attatgaaga tgcttttgaa ataatagaaa atgcgtctaa
    33181 taaaggtgtt ttagaaggtt actttaaaaa gcttgaaaag aaaaaaaatt taggtcaagg
    33241 tatatctagg catttagaat aaaaaaagtt aaatgtgaga aaataagttt aaataaactt
    33301 taagaggtga catcgatgaa aaaattagct agtactgctt tggctatatt aattgcgctt
    33361 actcctttaa gcttttcttt tgcaaataat aaggaaaatg ctgatgccaa ccaactaaat
    33421 atatcttcaa aatcagcaat tttgatggat gttggtagtg gacaaatttt atatgaaaag
    33481 gatgctcata aaaagcttcc tcctgctagt gtaactaagg taatgactat gctacttata
    33541 gtagaagctt tggattcagg caagattaag cttgatgatg aagttcaagt aagtgaaact
    33601 gcatctagta tgggtggtag tcaaatattc ctagagccag gagaaactca aaaggttgat
    33661 acattattaa aaggtatagc tgttgcttct gcaaatgatg cttgtgttgc tatggctgaa
    33721 cacttagctg gaagtgttga aggatttgtt gatagaatga atgctaaagc aaaagagtta
    33781 aatatgaatg atactcattt tgcaaataca aatggacttc cagttgcaaa ccactataca
    33841 tctgctcatg atatagcttt aatgtctaga gaactattaa aacacgaaat gataagtaaa
    33901 tacttaacta catggatgga taaggttgta gtagggaaga aacaagttac agtaggtctt
    33961 gcaaatacta ataaacttat aaagcattat caaggagcaa ctggtgttaa aactggtttt
    34021 actcaagaag caaaatactg tttatcagca tctgcaaaga gaggtaatac tcatctagtt
    34081 gctgcaactt taggagcaga gacttctcca gaaagattta atgatgcctc tagcctttta
    34141 aactatggat ttgctaatta tgaaagtgtt aagttatgta gtaaaggtga taatatagca
    34201 acacttacat tggataaggc tgatgaaaac aaagttaaat tggttgctaa agaagattta
    34261 aatgctctta ttaaaaaagg aagttctaaa gaatttgaga agaaaattga aatagtaaaa
    34321 aatcctaaga tgccaattaa aaagggaact gttttaggaa aaataaagat atgtaaagat
    34381 aaaaaagtaa taggcgaagt ggaattgata aatactaagg atataaataa ggcaagctat
    34441 ctacaaatgc ttcaaagaat aattgataat atgatataaa taattatcag atgaaatata
    34501 attataatac acaaagatat gattataata cacataaaaa atacccttat gtaattattt
    34561 gccatagggg tatttttatt taccatatag aagtatttta taatcttatg atttttatag
    34621 aaatatagaa aagtttatgt atcttaaaat atcatttgat ttaatatcat atatagggtt
    34681 gtttaacaat tatctaagta aaggcatact accagtaagt ttattcactt tctttttatt
    34741 cccataaatt gctatcccaa aatactgtaa ctcatcttct ggaacactag caatcttttg
    34801 tgtaaattct tcataaagat tgcaactttg tgctacatct gaaaaatcta caacagttaa
    34861 atcgttaaat tccaaagtat ataatttttt acgtaaatct tttattattt ctttgtttcc
    34921 ttttaaaata ggtacaggaa tgtcaataat tcctaagtgg ctattacctg ttttgtcaat
    34981 tacatctggg ccaacagttt ctggggcatg ttttcctagt gtaattccca ttatagctgc
    35041 tgtattggat ataattccca ttggtaaatt ttcgtctatt accatgacac attttgaatt
    35101 tttattttcc atttttattt ctccttttta ccttatttaa agttgtttga atcatcattt
    35161 ataaatatat tttgatactg ctttggtgta agaccaataa aattcttaaa aaagtttgta
    35221 aagtgacttt ggtctacaaa tcctgtttgt atcgcagcat ctataggttc tacgcctttt
    35281 tctaaaagct ttttagcttt gtttacccgt atattttcta ggtatctata tggtgtaata
    35341 ccttttaatt tcgtaaaatt acgaagtaga gagtacttat tcatacctgc tatagtgctt
    35401 aattcgtcaa gtactatatg ttcagcataa ttattttcta gataatcaca tactgcttga
    35461 atttctatat ttgtattttc caagttagat tgcaaatttg gctctgtatg ttcttcaatt
    35521 aattgttcaa ttaggaagaa aaaaagctct tcctttttaa aatccaattc ttcttccatg
    35581 attatatagt gtaattcttg tagtagaggt actagctcac tgcgaaatat aacaggttga
    35641 ttaaattttg gtaaataatt tttacctgta atttcaaaga cggttttttt cattatttct
    35701 ggcttaatat taatacatct gtaatcaagt actttatcat ctatttgttc acaagtatga
    35761 ctatcaaaag ggttaaaaag tagcaaatct ccagtacttg tggtatactc tttattttta
    35821 caagataaat atctttgacc tttttctata aaaccaatta cataatgttc atgaaaatgg
    35881 tttgggaatt tttgcattat gcctttaaat ctatatgctt caatttttaa ttccctatca
    35941 aagcatactg tgcgttcttc ttgtctcact taggtaacct cctttcatgt tatacaaagt
    36001 gtaacacata tttttttata cttcttgtat aatattgact aagagacaat aatgtcaatt
    36061 catgtcaata taatattaca cttacagtag gtgtaattat tatattttca caatgaatat
    36121 gatataataa taaaagttat aaaataaaaa gcaaatttta attttatgcc tagaagttaa
    36181 aattattata atgtaaaata attttgatta taagctattt aattgttata ataatattaa
    36241 aaatttaatt taggagatgt acattaatgt taagtatgaa tataggagaa atagtagcaa
    36301 gtttagttgg tatagctatg gcaatatcaa tacatgagtt tgggcatgct tattcagctc
    36361 acttattggg agatgataca gctaaagctt atggtagaat gacattaaat cctgtaagac
    36421 atgttgaccc aataggtctt ttggctatgt ttatccttaa gatagggtgg gcaaagccag
    36481 taccagtaaa tccaaataac tttaaaaact ataagatagg aaacctgata gtttcacttg
    36541 caggcgtttt ttgtaatgtt ttgactgcta tactgtgtgt aattatcaat aagtatgtgc
    36601 atatgtatgc tataaataca atagctggat atgtgctttt atatagtatg ggatttgcag
    36661 cttttaactt acttccgata cctccacttg atggatgggg agttatatct acatttgtac
    36721 catataaatg gaatgaatat ttgtataaat ttgaaagtat gagttatata attttattaa
    36781 ttgctttatt tactggtatg tatagaataa tattaacacc aatatatgca gtgttgctaa
    36841 aaatagtata tttatttgtt taatataata aacagattaa agagggattg atatgaagta
    36901 taatatacaa ttacaagtct atgagggacc attagattta ctttatgatt taataacaaa
    36961 gcataaaata gatataaagg atatatccat aatagatata actaagcagt atctaaatta
    37021 tttgaaaatg ctagataaaa tggatttaga gataactagt gaatttataa ctatggcatc
    37081 aaaactttta gagataaagt ctaaatatct gctttataag caaaaagatg aagaagaaga
    37141 cccaagaata gaacttatgg aaaagttaga agaatataga aagtttaagg tagcatcaca
    37201 agatataaaa gaaaatataa cttatgttaa tgagagattt tatagaaata aagaagagat
    37261 aattattgat gacaatgtgg atttagaaga tatatcaatt gaagcaataa aaaatatact
    37321 tccatacata tttaaagtta aaacatcaca gatagaaaat gctaatgatg agaaactaga
    37381 taaaatagta aggaagaaaa taatatctgt agaagaaaaa atattatata taagagatat
    37441 tataaaagag aagattgaag ttacttttac aaatattata aaatcatatg aaaatgatga
    37501 aataatagct acttttttat ctatattaga gcttataaaa gaaaaagaaa tagtcgtagt
    37561 acaagatata ttttttgatg atattctaat aagaaaaagt tcggagtgtt aaaatgaaaa
    37621 gagaagatat aaagtatatt atagaatctg ttatgtttgc atatggtgag ccaataagta
    37681 taaaagaatt aaactatata ataaataaag aactttcatc aaaagaaata gagattatgt
    37741 taaatttact tattgaggag tacagagaac aaaatagagg tattcaaata atcaagttag
    37801 agaataagta ccaaatgtgt acaaataaag actatgcaga atatataaag aagattattg
    37861 aaccaaagaa aaagaaaagt ttgagccaag ctacattaga aactcttact ataattgcct
    37921 acaaacaacc aataacaaag gtagaaatag aggatataag aggagtaaaa tgtgataagg
    37981 tattacaaac tttgtttgaa aatgaactta taagagaagc tggtagattg aataagatag
    38041 ggaaaccaat aatttataaa acaacagatg aatttttaaa gttgttgaat atagaaagtc
    38101 ttgaagaatt gccacctata gaaaattatc aagaagtggc aacaaatgaa taaaaatata
    38161 aaatcacaat aatttagtat gtaattttaa attttaaaag atttaaaatg ctctaagttg
    38221 ttgtgttttt ttgtataaat ataaaattat aattctctta aaataaatat ggataattaa
    38281 gtataaatag taattttttg atgataatat aaacatggag cttaatgaat tatttaattt
    38341 taagtattta ataatagctg taatttttat tataagtgta actatgttga ttttaatatc
    38401 tcatataaac atcttaataa tagctgatat aaaaaacaaa gatatttgtt taaagcttaa
    38461 tataaaatac atgtttaatt taataaatat aaatagacaa ctttatccag ctgaaaatag
    38521 taaaaataat gataaaaaag aggggatgaa gaataatata gattcaagta tattattagc
    38581 tgatgacctt ttgagcattt atagattatt aaaaaagata aaaatacatg aactttattc
    38641 aaatattaat tttggaactg gaaatattgg cttaacatct tctgtatatg tattgataaa
    38701 tactttgtat ggaaatttat ttaatatgat tgatgcagaa aaaatgtatt taaatgtaaa
    38761 tccagatttt acaaaagatt atgttttagg aaatataagg atacatataa ggccaagaat
    38821 aaaagcttta tttaatatta taataatgat taataaaatt atgaataaaa ataaaggaaa
    38881 taaggaaggt gatagtaatg agagcaacag gttcgataca gagtcttatg gaaacaactc
    38941 ttgaaacaat taaaggttct atagatgcaa atactattat aggagaccct ataaaaacag
    39001 atactacagt ggttgtacct atatcaaagg ttacaattgg ctttggtata ggaggaggag
    39061 aatactcaaa aggatatgat gataaagata gggaaattga attaaaaaat gaaaaatcag
    39121 atacgaattt tgctggaggt agcgcagggg ctatatctgt acaaccagta gcatttgtag
    39181 tagttgaaag tggagagact agaataatga gtttagacag taatatcaat ctagtggata
    39241 atatattatc tataactcct agagtattgg agaaaattca aaatatatca caaagtaata
    39301 agaatcaaga taaaaacaat atgtaagaat aaaatatttt taaatatgta tatagtttta
    39361 ggtaaagtag tggggttagt ataaatccca ctattttgtt gtgtacttta aacatttata
    39421 tctaataaga ttttagttta aaacaattta aatagataat aaagttgata tatagtataa
    39481 ttataaaaag aaaagaagta ttatattata gatatataaa cgcatttgag atataagagg
    39541 gagttataaa tcattagttt tgaggtgaat gttatgagcg ataaagaatt atctattttg
    39601 ttgttagaaa gtatgaataa ttttcataat ttaataaaga ttattaataa cgaaagatat
    39661 aaaaaagata aggttcttac agaaagacag ttctttgcct tagtaaaaat aagaaaacat
    39721 gataaaatag agcttaaaaa tctaagtaga gatttgcatg tatctacttc tagtctgtgt
    39781 atactactta ataaattggt tgagcaagag tatgtatata gggaagaaga tagtagagat
    39841 agacgaaata ctttttatgg aataactaaa aatggagaaa agatattgga taatgaaata
    39901 ctaaagtttg tatctataat aagtgataaa atggattgcc tagatataga taataaagat
    39961 aaattattta cttctttgga agagtctaaa aatataatag aacaattatt ttaaaaagga
    40021 gaatttatta tgaatataaa gtattctaaa gaaatattaa aaagtttaga aaatgctata
    40081 acagtagtag ctctatttga gggagaagat gtttctacga catttgataa aataaatatg
    40141 ataagcagaa attttaattc taaagaaaat agtatagata ctgtaacatt gattgaaaat
    40201 aacaatttgg taaatgtttg tcttgttggt tttggtaaga gagagttatt gaatagagaa
    40261 aaaattagaa tcataggtgg taatttgtgt aaaaaattaa aaaatatatt gaaaaatgaa
    40321 gcatataaga gtagtgatgt taatgtactg aatcttaatt taaatagtga tgaaataggt
    40381 tcttttgtag aagggatatt acttggaaat tataagtttg ataagtataa gacaaaaatt
    40441 aaggattttg aaagaaaaga agttgatact ataactatat ttactgaaaa agaagttgag
    40501 tgtcaaatag aaaaggctaa aatattagct aattcaacta taatagctag aaatctagtt
    40561 aatgaaccat caaacgtaat atatccaaaa acattagcag tagaaacagt taaacttggt
    40621 gcagagtttg ggtttaatgt tgatgtttat gaagaagaaa aaataaaggc attgggaatg
    40681 gatgcttttt tcgctgtttc aagaggctca attaataaac caagattcat agtaatgaga
    40741 tactttggag ataaagaaag tacagatata ttaggtttag taggtaaagg attgacttat
    40801 gatactggtg gatattcttt aaaatcaaat gcttctatgc tagatatgaa gacagatatg
    40861 gctggtgctg cgagtgttat aggtgctatg tgtgctatat ctcaaagtaa attaaagaaa
    40921 aatgttatag cagtagtggc tgcatgtgag aatgctttat caggaggttc atacaaacct
    40981 ggagatataa ttagttctat ggcaaagaaa actattgaag ttttaaatac ggatgcagaa
    41041 ggtagactta cattagctga tgcaatatac tacattataa acaatgaaaa agtaacaaag
    41101 gtggttgatg tagctacatt aactggtgct gctttaacat tgttaggtaa tgttgcaact
    41161 cctatagtaa caaataatga tgatttttat tgtgaattag aaaaagctgc cactttatca
    41221 ggggaaaggg tatggaagat gccaatttat gatgaattta aagatatgat aaaaggagaa
    41281 gaagcagacc ttaaaaacac tggtggtaaa aatgctggat gtataacagc aggagctttt
    41341 attggtgaat ttgttgggaa tactccttgg atacatatgg atatagcggg gacaagtaca
    41401 tcatcaaaat caattggata caaagcaaag ggggctacag gagaacctgt tagaacattg
    41461 tactatttgg cagaaatcta aaaaacaatt ataaaatata atttataaag ccacgtggat
    41521 atttttgtaa tttaagatta tctatgtggc tttatttttt atttaaataa attatttact
    41581 ctttttcttt ttttcaagta taaaagtatc tctattaaat aaaagagcag gtatgtacat
    41641 aatactagta acaaaaataa acgtaaaaat agcagttgtg ctatgactta aaaaaccata
    41701 atagtaccta gagttggtaa atgtgtttag taaaaatatg aatgaaaaat aaataaaaca
    41761 tatagctaag ttatctctaa gtgcatatct gttaactcta aattttctaa catcaaccat
    41821 atatatatct gcataaatta tcaagcactt agagaagata aagataaaat atattaagct
    41881 aggaaattca tagcccaagt ttttagaaaa aatgagttct ccaactgaac aaactaaact
    41941 ccaagaaaaa aatatattaa aaagatgata ctgcttaaaa attagtatgg ctatacacag
    42001 atatatacaa atataattga ttccaattgg taaagagttt agagtactat aattacctga
    42061 agaaataagt aataattgct ctagagccat aattattaca agtaatgtac aaattatctt
    42121 ctcaactgta tagctataag gtaaaatatt tttggttagt tttggacaat agtataaaaa
    42181 taatccaaat ataaagagat ttacaaattg ttcactagaa aaaagaaaaa ttttaaacat
    42241 ataacattct ctcctataat aaatttaata tgtatctata taaatatatt cattatatct
    42301 caatttaata tataaaaaag ataataatag ttagattttt tatatgaatt ttaataggta
    42361 aaatatccta ttgttttgta gatatatcct aattatgtca aaaaataaaa aaaattttat
    42421 ttattagagt ttttggaaat aataataaca gatattataa ttaattaaca gtttttgtaa
    42481 gtatttgaca atagagaggg tgtaacaaat gggaataata gagtcagcat caaaattggc
    42541 tgagatggtt catttattgg ctgttgaaaa ggggataact gatatagaag catgggatga
    42601 agctgtgaaa gaatacagca aaatttatga agaaagaaga aatgaataga atgataaaaa
    42661 atgaaaactt gatgataaaa aataacttta tttaaagaaa ttcaattttt atagaagtat
    42721 taaaaataat ataaataaaa agatggtatt tcaaatgtaa gtaaaaaatc attttgggat
    42781 accatcctta ttatttattt taataatata taagtaataa atcttactta tccatatttt
    42841 ttatgtaacc tcttttttct aactttttta tatgctcctt acgtatttca tcaagattaa
    42901 taccatattg ttcttctagc ttaaacatca tagtaacaca tgtctgcgct acatccatta
    42961 gttccttagc agttttcttt ataatatcaa cttcatctaa atcattattt tctccactta
    43021 gatttctgaa tttacctata cattcagcta attcaccttg ttcttcaccc attttgataa
    43081 atgtagattc tagtgttggg tctaaattat taagctctgg taaagatata gtttttagtt
    43141 tcataaaagc tcctttcaag ttattcgtat ttatactaaa acatcataac aaaaataata
    43201 ctaaaaaaaa actttaaatt caacataaaa acttacatat ataataaaaa tcgtgaaata
    43261 aatctatatt tgtcttaata cagcctcata taaaacttct ccaataggtt tatttattac
    43321 aagagaagct gacttatcat agactgtatt tgctttatta ataagagcaa tataatcacc
    43381 tttgtaataa tctataaaac ttgctgctgg gtacacagct aatgatgtac ctcctataat
    43441 caataaatca gcattactta tagcagaaat tgttttagta atgacatcac tgtcaagagc
    43501 ttcctcataa agtactacat ctggttttac tatagaacca cagttgtcac agtaaggaat
    43561 attacctccc agatttaaca tagattctaa gtcaaaaaac ttaccacatt tagtacaata
    43621 atttctatgt acagaaccat gaagttctag cacattttta cttccagcca tttgatgaag
    43681 tccatcaata ttttgagtta tgacagcttt aagcttaccc atttcttcga gttttgctaa
    43741 agctatatga gcattattgg gttttgcatt aggatatatt aatttatcct tataaaattc
    43801 aaaaaattct tctggatatc taacaaaaaa agtatgtgaa actaattgtt cagcagtaaa
    43861 ttgtttattg agtttttggc taaataatcc agtagaactt ctaaagtctg gaatattaga
    43921 ttcagttgaa acacctgctc caccaaaaaa tacaatatta ttgtgattag ctattaagtc
    43981 ttttaagcta tttgcatcca tagttacacc tccaaattat tatatataaa ttgtactaca
    44041 tattaggtcg tttatgtttt attaatttaa ataaatatat agtttaataa gttaaataaa
    44101 gggaatataa ataaaatgta tacagagtat aaatagacaa tatttactaa aataacaagt
    44161 tgtcgtataa ttatattaaa attgttttag tgtataagaa gggcggggga agtacgtgaa
    44221 gaaaaaagca gctttagcaa cattggctat gttaccctta ggtgtggtaa atgcacatgc
    44281 tgatggagat ataggtatag tgactataaa ttatttaaat gtaagaaatg aaccaactgc
    44341 cgaaagtagc atagcctttg ttgctaaaaa agatgataaa gttttgatta aagactcttc
    44401 taatggatgg tataaaataa aagctgaatc tggacaagaa ggttgggctt catcaaaata
    44461 tatagcaaaa tcaaatagtg actctttaag aacgtctaca aataaagaaa aacaagttat
    44521 ttcaaatagt ttaaatatga gaaatggagc aggtacaagt tacagagtaa taactgtact
    44581 aaaaaaaggt caaaaagtag aagtaatatc agagagtaat ggatggtcta aaatcaaata
    44641 tgatggaaga ctaggatatg tatctagctc ttatttagga gacgtttcaa actcaactaa
    44701 taaatcaaaa actaaacaag tgaatacaac ttcactaaat gtaaggagtg gaccaaatac
    44761 aagttatggt ttgttaggca agttgccaaa aggaagtaaa gtagaagtaa tatcagaaag
    44821 taatggatgg tcaaaaataa agtataatgg aaaagatgcc tatgtatcta gtatgtactt
    44881 atcggatgta agtcaaagta attcagacaa ttctagtcaa agcaatgata aaaagaatac
    44941 tgataaggtt gtaaatacag cttctttaaa tgtaagaagt ggaccaggtt ctacatatag
    45001 taagttggga aaagtttata aaggaagtaa agtaactgta ctatcagaaa gtaatggatg
    45061 ggctaagatt aattttaaca ataaagaagc atttgtagta ggcaattatt tatctacttc
    45121 agcagatact tcaaataata actcaaatag taactctgat aacagttcta atagtaatgg
    45181 caataattct tcatcatcag gtcaagtaaa tggtatgtca ggtataagtg gggctaaaat
    45241 tgattataaa tctttgagtt atactttaga atctcatata agtaaacaag ttgagaaagc
    45301 agcatcagga ggaaatgtga tagctccaag taataggaaa agcactccaa gtcctgaatt
    45361 tagtactttt tcagctcaaa gaacaagctc atttgtaaat gcaagttcaa gtgatataga
    45421 atattattta aatcctaaga attttacaaa tactactaaa ggtatgatgc agtttttaaa
    45481 gattaacagt tatagagatg gtatttcaga atcaagtctt aactcgtatc ttaatggttt
    45541 atcttctagt gtatttaaaa accagggagc agcctttata aatgctgcca agaagtataa
    45601 tatagatgtt gtatatctag tatctcatgc tatgtgggaa actgcttatg gtaagtctac
    45661 acttgcccaa ggtcaaacat taacatctta taagggacaa cctcttagta agccagttaa
    45721 agtatacaat ttttttggta taggagcaat agataaaagt gctaatgttt caggtgcaga
    45781 agcagcgtat tccaatggct ggactagtgt agaagctaca atagatggct ctgcaaagtg
    45841 gatatcacaa aattacgtaa atagttctaa gtacaatcag aatactattt acaagatgaa
    45901 gtggaattat gattatacat ggcatcagta tgcaactgat gtaaactggg ctaatggaat
    45961 ttctggaatt atggaaaatt taattggtct ttatggagga ggaagtagtt tggtttttga
    46021 agttcctcaa tataagtaat acataaataa aaaatataga ctatgggtag ttttcatttt
    46081 atttaaatta tctatagtct ttttgtatat aatttataat ctgtaaattt aatgttaaca
    46141 aaacttttat gttataatat taattctaag taaatataag tgagtaatgg gtagaaatag
    46201 ataaaaagtg gtaataatat atataaagat aattttgaga aaggaggata tatatggaaa
    46261 gtattaagga atatttggat aagttagaaa ttaataatag tggtcttgga aagcaactta
    46321 aagaagttta tataaataga gtagtttatt ttaaggaaga taagatagtt tatttttatc
    46381 taacttctaa agatattgtt tctcatgaac ttttagataa atttaaagaa gaattgatgt
    46441 ataaactcga ttattttaaa gatatgagga tgaagataag atttactggt cttgaaagaa
    46501 aatccaataa agatgttata aaaaaatatt ggaataatat attgtatata ttaaagtatc
    46561 tttgtccatc tattgcaggg tggtataaac aagtagaatt tctttgttta gaagaagaat
    46621 taaaaataaa acttccaaaa ggtatatttt atgagcgatt aatgaaaaaa aatgtaactt
    46681 atgtacttaa aaccgtgctt agcgaagagt tgggattaga tttaaatata acaatagaaa
    46741 aagctgttga tgaaaaggta aataaagaaa gactcataag aatcaatgat agagaaatgg
    46801 aagaaaaaat tagggcttta gaaattggaa aagttaataa ctgtgaagaa aatgaagagg
    46861 aaagttatgt cattaagtct gatgtagatg aaaatttaat ctatggagat aatgcaaatg
    46921 ctatgattga aaatatagtt gaattaaatg catcttctgg aacagttgca gttgttggag
    46981 atatatttga tgttgacact aaagaactta aaaacggaaa aatacttatg atagcttcaa
    47041 ttacagatta tactagctca ataagctgta aacttttttt aacagataca aataaggatg
    47101 gagtacttga aaatgttaaa aaaggagcat acttaaaaat caagggtgac atagtttatg
    47161 atacatatca aagagaaatt agtatgatga ttagtgggat aagaaaagaa actagaatag
    47221 agagagaaga taaatcagag gaaaaaagag tagaactcca tgcacataca caaatgtctt
    47281 ctatggatgc tatttgttct gttaaaaagc ttgtagagcg tgcagctaaa tggggtcatt
    47341 ctgctattgc tataacagac catggtgttg tacaaggatt tccagatgct atgaatgcag
    47401 gtaagtcaaa taatataaaa atactttatg gagtagaagg gtacttggtt gaagatgatt
    47461 ctctcattat agaggatgca aatgataaag aactttcaca gacatttgtt gtatttgaca
    47521 tagagacaac tggtttttct aatacaaatg ataaaataac tgagattggt gctgtaaaaa
    47581 tagaaaactt taagattgta gatagattta gtgagttaat aaatcctgaa aaagatattt
    47641 cttataagat acaggaattg acaggaataa ctaatgaatt aattaaagac aagccaacca
    47701 ttgaagaagt tcttcctaag tttatggaat ttgttggaga tagtgtatta gtagcacata
    47761 atgcagagtt tgatactgga tttatatcgc aaaaatgtag ggaacaaggc ttgttatata
    47821 ataacaaaaa agtagataca cttatgttag caagagtaat gttgccaaac ttaaaaagac
    47881 atagattaaa tgtcgttgca aaagaacttg gtattcctct tttaaatcac catagagcag
    47941 tggatgatgc tgaagctaca gcacttatat ttaataagtt tttgcagatg cttacagaaa
    48001 aaggtgcaaa aactctaagt gatgtaaaca atatacttgg aaagattgat tacacaaagc
    48061 ttagcacaaa tcatataacc ttgatagcaa aaaattctat aggtataaaa aatttatata
    48121 aaataatttc agatgcacat gtaaatcatt tttttagagc accaagaatc cttagaagtg
    48181 tattaaatga atataaagaa ggattaataa ttggttcggc ttgtgaagct ggggtggttt
    48241 ttcaagctgt aaagaaaaac gtgtctgatg aggaaatgaa aaaaataata gatttatacg
    48301 attatattga agtaatgcct atagataata atagatttat gattgataaa ggagaagtaa
    48361 aggacgaaga agagttaagg gagttgaata ggaaactaat tgatacagcc aaaaaatttg
    48421 acaaaattcc agtagctact ggggatgttc attttttaga caaacatgaa gctgtcttaa
    48481 gaaaagttct taaatattct caaggtttta aagtagatga agaagaaact tatttacatt
    48541 ttagaacaac agatgaaatg ttggaagaat ttagttatct tggagaagaa ttggcatatg
    48601 aagttgtagt tgaaaatagt aatctgattg ccgatatggt tgaagatata aaacctatac
    48661 cagatgatac ttatcctcca attatagagg gctcagatgt ggagttaaga gaaatgtgtt
    48721 acaaaaaagc caaacgaatc tatggagacc caataccaga aatagttcaa aaaagactgg
    48781 atagagaatt aaattcaata ataagcaatg ggtatgcagt tatgtatatt atagctcaaa
    48841 aactggttgc aaaatctctt tcagatggat atttagttgg ttcaagaggc tcagttggct
    48901 catcttttgc agctactatg agtgatataa cagaagttaa tcctcttcca gcacattata
    48961 tttgtgaaaa cgaagactgt aaatattcat tcttttatga aataggtgaa tggggctcag
    49021 gtgttgattt accagacaag gattgtccaa agtgtggaag aaaacttgct aaaaacggtc
    49081 atgatattcc atttgaggtt ttcttaggtt ttgaaggtga taaagaacca gatatagact
    49141 taaatttctc aggaaattat cagccaacaa ttcataaata cacagaagaa ctatttggag
    49201 aggggtatgt atatagggct gggactatag gtactgtagc agaaaaaaca gcttttggat
    49261 acgcaagaaa atatgtggaa gaaaataata taagtgtacc aaatgcagaa gtacttaggc
    49321 tttcaaatgg atgtactgga gtaaaaagaa cctcaggaca acatcctggt ggagttatgg
    49381 ttataccaga ctataaagat gtatacgatt ttacacctat acagtatcca gcaaatgata
    49441 cttcttgtgg tgttataact actcactttg attatcattc aataagtggt agaatactta
    49501 aacttgatat acttggacac gacggtccta ccattataag gatgcttgaa gatatgactg
    49561 gaataaatat aacagaaatt cctttagatg ataaagagac tatgtctcta tttacatcta
    49621 cagaagcatt aggtgttaca ccagaagaaa taaactgtcc tataggttgc cttgctgtac
    49681 cagagtttgg aactaagttt gtacgacaaa tgttacttga cacaaaacct actacatttg
    49741 cagaacttgt acgtatatct ggtctctctc atgggacaga tgtttgggta aataatgcac
    49801 aagacttagt tagagaagat atagttggat taaaagatgt tatatctaca cgagatgaca
    49861 taatgaacta tttaatattt aaaggattac ctcccaaaat gagttttaca ataatggaga
    49921 gtgtaagaaa aggtaaaggt ttaaaaccag aacacattga agaaatgaaa aaaaataatg
    49981 ttccagaatg gtatataggc tcatgtaaaa agattaagta catgttccca aaagcacatg
    50041 ctgttgctta tgtaatgaca tcatttagaa ttgcatattg taaagttcac tatccagaag
    50101 cattttatgc gacttatttt acgacaaaag ttgaggattt tgatgcagat ttaattgtta
    50161 aaggattaga tgctataaaa tcaaaaataa atgaaattga gtcactggga aatgatgcaa
    50221 ccacaaaaga aaaaggtatg ttgaccgttt tagaagttgc tcttgaaatg tatgctagag
    50281 gaataaaatt attaccagtt gatatatata aatcagatgc aactgagttt atagttgtag
    50341 gagaaaaaac attacttcca ccaatggcag caatacaagg tcttggagga aatgcggcta
    50401 taaacatcca aaatgaaaga aaaaatggtg aatttatatc aaaagaagat ttgagaaaga
    50461 gaacaaaaat atcaaaaacg gtaatagaaa ctcttactaa tcatggttca cttgagaata
    50521 tgagtgagag aaatcaattg tcattgtttt aagttagccc aaaaagttgc aaataaaaga
    50581 attttatgat atcatagtat agaaaatagt atactttgca gaaactaaga gtgagacagc
    50641 tgttctcact cttttatttt aaatatatta ttaaaaatct ggtttatttt tattaaatat
    50701 attttattta agattatata aactggtcat ttacaattga ataggaggaa ctttaatgaa
    50761 aaaaaattta gaagctacaa ttgaggagat tgtaactaaa ataacggatg aacatggatt
    50821 tgaaatggtt gatgttgaat atgtaaaaga agcaggagaa tactacttaa gagtatacat
    50881 agataaagaa gaaggaatat ctttaaatga atgtgaatta gttagtagag aattaagtcc
    50941 aatactagat gaaaaagacc ctataaaaga aaattacttt ttagaggtat cttctccagg
    51001 acttgataga gcattaaaaa aagacagaga ttttgttaga tatcaaggta gagatgtaga
    51061 tttaaaatta tataaaccat taaatggatg taagcaattt gaaggtgaac ttgtaggatt
    51121 aacagaagat aataatataa aaatcattgc aaatggtaag gaaatggaat ttaatagaaa
    51181 agatgttgct attgtcagat tagcaataaa gttttagtgg tatattaaat agggaggata
    51241 taaaaaatga atcatgaatt tatggaagca ttagatgaat tagtagttga cagaggtata
    51301 gataaagaaa tacttataga tactatagaa caagctcttt taactgcata caagaaaaac
    51361 tttggttcag cacaaaatgt tagagttgaa tttgatagag acaagggaga tataaaagta
    51421 ttttctcaaa gagttgttgt tgatgaatca gatttatatg atactttctt agaaatagag
    51481 ttagcagatg ctagagagat aaatcctaat tatgaattag gtgatattat agaacatgaa
    51541 gttacaccta aaaactttgg aagaattgca gctcaaacag caaagcaagt agttgttcaa
    51601 agaataaggg aagctgagag agaaatagtg tataatgaat ttatagaaaa agaaaatgaa
    51661 atagttacag gagaggttgc tagagcaaat aaaaatgttg tttatgtaaa tcttggaaga
    51721 atagaaggta taatgactca aagtgaacaa ataccatttg agaattataa agcaggtcaa
    51781 aaaataaaat tctatatact tgaagttaaa aagactaaca aaggacctca aatagttgta
    51841 tcaagaagtc atccgggtct agtaaagaga ttgtttgaag aagaagttcc tgaaatatat
    51901 gaaggaatag ttcaaataaa atctgtagca agagaagcag ggtcaagaac taaaatggca
    51961 gtaagatcta tagatgaaaa aatagaccca attggagctt gtgttggacc aaaaggactt
    52021 agagtaaaaa atatagtgga tgaacttggc gatgagaaaa tagatataat aaaatatagt
    52081 gaagacccag cagagtttat atcagcagca cttagcccat caaaagttgt tagagtagat
    52141 atagatgaag atgaaaagtc tgccttagta atcgttccag attatcagtt atcgcttgct
    52201 ataggtaaag aaggtcaaaa tgcaagacta gcagcaaaat tgactaactg gaaaatagat
    52261 attaagagcg aatctcaagc agaacaagaa atgttaaatc ttgaaaattc caaagaaata
    52321 gaagctgagg atgttgaagc tgaatttatc gaccaagaag agttagatac ttcagaggat
    52381 aattttagtg aagaagagta aggagggatg attttgaaaa aagtaaaaaa agtgcctcaa
    52441 agaaaatgca tagcatgtca agatagagac tctaaaaaag agcttataag aatagttaaa
    52501 aataaagaag gaaaaatatt tttagaccca acaggaagag ccaatggaag aggagcatat
    52561 gtatgtaaaa gctctgaatg tctaaaaaaa gctataaaga gtaaagcatt aaataaagct
    52621 tttaaaatag atgttcctga tgaagtctat gataatctac ttatggagtt agaagaatat
    52681 gaaaaataat aaagaaaaag tactttcgtt cttagggctc gcaactcgtg cagggaaaat
    52741 agtgtctggt gatgattcaa ctttgcttga ccttaaaaaa ggaaaagtaa atttgatttt
    52801 aatcgcagaa gatgcatcaa ataatactaa aaaacttttt aaagataaat caacttttag
    52861 aaatattcca tatctatttt tttcaacaaa agaggaaata ggatttgcaa taggaaaatc
    52921 tccaagagca gttgtaggaa taaaagatga aaatttttct aaaaagataa ttgaactaat
    52981 agaaatttaa aataaaatag ggggtgatct tgtgtcaaaa acaagagtat accaaatagc
    53041 agaagaatta aatatatcaa atgaagagct tataaataag ttagctgaat tagatataaa
    53101 tgtaactgac aaagattcag tattagaagg tgaagagtta gaattagcac ttgaaatgtt
    53161 aggtgaagat ttatctcaag aaaatggaaa tgttatagaa atagatggaa agttgacagt
    53221 acaagtatta gcaacgaaat tagataaatc tccatcagaa ataattatga agcttatgaa
    53281 aatgggaact atggcaacaa taaatcaaga gataagtttt gagattgctg ctttggctgc
    53341 caaagactat ggatttgaat taacagtagc tgaaagtgat gatacagaag ctttagaaat
    53401 agaagcttta atggaaattg aagaagacaa agaagaggat ttaaaaccta gaccaccagt
    53461 tgttacagtt atgggacatg ttgaccatgg taagacatct ttactagatg caataagaaa
    53521 aactgatgtg atttcaggtg aagctggagg aataactcag catataggtg cttcagaagt
    53581 taaaatcaat ggacacaaaa tagtattttt agatactcca ggacatgagg ctttcacatc
    53641 aatgagagca agaggagcac aagttacaga tatagcaata ttagtagttg cagcagatga
    53701 tggtataatg cctcaaacag ttgaagctat aaaccatgct aaagcagcag gtgtaccttt
    53761 aatagttgct attaataaaa tagataaacc aggtgcaaac ccagataagg ttaaacagga
    53821 attagcagac caaggattat tagttgaaga ctggggtgga gaagtaatag cagttccagt
    53881 atcagctaag aaaaaagaag gaatagatac acttttagaa atggtattat tggttgctga
    53941 aatggaagag ttaagagcta atccaaataa aagagcagta ggaactgtta tagaagctga
    54001 gcttgataaa ggaagagggc cagttgcaac agtacttgtt caaggtggta ctttaacagt
    54061 aggtgaccca atcgttgcag gtgttgcatg tggtaaagtt agagcaatga taaatgcaaa
    54121 aggtaagaga gtaaaaacag caggaccatc tacagcagtc gagatattag gtctatcaga
    54181 agttccacaa ggaggagacc aatttgtcga agttccaact gataagattg ctagaagtgt
    54241 agcagcaaga agacaacaaa tagttagaga tgaaatgtta aaatcaactc aaagattatc
    54301 actagatgct ctatttagtc aaatgagtga aggttctata aaagacctta atatagttat
    54361 aaaagcagat gtacaaggtt cagtacaggc agttaaacaa tctttagaaa aattatcaaa
    54421 tgaagaagtt caagttaaag taatacatgg tggtgttgga gctgtaacag aatcagacat
    54481 attacttgca gcagcttcta acgcaataat aataggattc aatgtaagac cagttccagg
    54541 tgcagaatct ctaggagaaa aagaaaatgt tgatataaga acatatacta taatatacaa
    54601 ggcaatagaa gatatacaag cggctatgac tggtatgtta gaccctgaat atgttgatga
    54661 agaaacagga aaagctgaaa taagagaaat atataaaata tctggtgttg gaacagtagc
    54721 tggatgttat gtgactaatg gtaagatatt tagaaattgt aaagtaagat tagttagaga
    54781 tagcataata atacatgaag gtgagcttgc agcacttaag agatttaaag atgatgtaaa
    54841 agaagttaat tctggatacg aatgtggtat gagttttgta aattataacg acataaaaga
    54901 aggcgatata gtagaagctt atataactaa agaagtagaa agaaaattat aaattcgtat
    54961 caaagaaaat cagttagtaa agaaggtcga tggtatggca tcatataata gaacaagaag
    55021 gatagcagaa gaaataagaa aagtcgtaag tactatgctt ataaatggag taaaagaccc
    55081 tagaataaca tctatggtga gtgtaactga tgtagaagtt acaaatgacc taagatatgc
    55141 ttatgtatat gtaagtattc tgggtggaga tgaagaatcc acactaacag gtcttaaaag
    55201 tgctggagga tatataagaa gagaagtagg aaaaaatata aaacttagat atattcctga
    55261 gatagtattt aaacttgatg attcaataga aaaaggaatg tatatggata gccttataaa
    55321 aagagttaat gaaaaaaatg ctcaacaaaa tgaggatgaa aattatgatg aataatatgg
    55381 atagtattat aaactatatt tatgagggtg actattttat agttacctct catatcagtc
    55441 cagatggaga caatattggt tctacacttt caatgtatta tacattgaag aatttaggaa
    55501 aaaatgtata ttatgtactt gatgatgaag ctccattaaa tttaaggttt ttggttgaag
    55561 gtgtaaaaat ctataagtct aatgaattta atatgaagaa ctattctcta attgcacttg
    55621 attgtgggga taagatgaga atctgtgtga gtgatgaaat caaaaataat gcatcaaaat
    55681 taatctgtat tgaccatcat gctagtaatg attcatatgg agatttaaat tatgtagata
    55741 ttgatgcatc ttctacatgt gaattagttt ataatttatt ggttagattt cagcaactaa
    55801 aagatattaa tattataaat gaagatatag caacatgttt atatacaggt cttgtaactg
    55861 atactggaaa cttttcgtat tcaaatgtac atgcaagtag ctttgaaatg gcaaaaaatt
    55921 tacttgtttt aggtgcacaa aaaaatacta taatacaaaa tatatatcaa agcaattctt
    55981 ctgattatta caaattatta ggagaagctc taaagggttt ggagatattt gattaaaaaa
    56041 tagttacgca cactcgtgac tttagtcatg agttagtagc taaaatagtc agcatatagg
    56101 gaaacctata tgtagagata ggatagaacc tatccaatac tacttgaatt gctggaaacc
    56161 cctaaagcta accaaactaa aacataagga tgaaataaac ctaaatgtga aagttacgaa
    56221 agtagaaaaa attggttaga tggtataagg ttaaacccta agtactttaa aatgggcaat
    56281 cagcaggtaa
//
LOCUS       DAEPUT010000017        55242 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.017, whole genome shotgun sequence.
ACCESSION   DAEPUT010000017 DAEPUT010000000
VERSION     DAEPUT010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55242
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.017"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            24..395
                     /locus_tag="KRL22_001158"
     CDS             24..395
                     /locus_tag="KRL22_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1271660.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            527..1801
                     /locus_tag="KRL22_001159"
     CDS             527..1801
                     /locus_tag="KRL22_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1271661.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNSTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            1912..2856
                     /locus_tag="KRL22_001160"
     CDS             1912..2856
                     /locus_tag="KRL22_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271662.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            3072..4409
                     /gene="rsxC"
                     /locus_tag="KRL22_001161"
     CDS             3072..4409
                     /gene="rsxC"
                     /locus_tag="KRL22_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBH1271663.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            4432..5409
                     /locus_tag="KRL22_001162"
     CDS             4432..5409
                     /locus_tag="KRL22_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HBH1271664.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            5409..5978
                     /locus_tag="KRL22_001163"
     CDS             5409..5978
                     /locus_tag="KRL22_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HBH1271665.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDDLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            5991..6584
                     /locus_tag="KRL22_001164"
     CDS             5991..6584
                     /locus_tag="KRL22_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HBH1271666.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            6599..7174
                     /gene="rsxA"
                     /locus_tag="KRL22_001165"
     CDS             6599..7174
                     /gene="rsxA"
                     /locus_tag="KRL22_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBH1271667.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            7190..8161
                     /locus_tag="KRL22_001166"
     CDS             7190..8161
                     /locus_tag="KRL22_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HBH1271668.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            8381..8965
                     /gene="maf"
                     /locus_tag="KRL22_001167"
     CDS             8381..8965
                     /gene="maf"
                     /locus_tag="KRL22_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBH1271669.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            9010..9669
                     /gene="radC"
                     /locus_tag="KRL22_001168"
     CDS             9010..9669
                     /gene="radC"
                     /locus_tag="KRL22_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBH1271670.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            9790..10800
                     /locus_tag="KRL22_001169"
     CDS             9790..10800
                     /locus_tag="KRL22_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH1271671.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            10810..11703
                     /gene="mreC"
                     /locus_tag="KRL22_001170"
     CDS             10810..11703
                     /gene="mreC"
                     /locus_tag="KRL22_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBH1271672.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            11718..12206
                     /gene="mreD"
                     /locus_tag="KRL22_001171"
     CDS             11718..12206
                     /gene="mreD"
                     /locus_tag="KRL22_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBH1271673.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAVIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            12218..15196
                     /locus_tag="KRL22_001172"
     CDS             12218..15196
                     /locus_tag="KRL22_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBH1271674.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            15294..15977
                     /locus_tag="KRL22_001173"
     CDS             15294..15977
                     /locus_tag="KRL22_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBH1271675.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            16001..16798
                     /gene="minD"
                     /locus_tag="KRL22_001174"
     CDS             16001..16798
                     /gene="minD"
                     /locus_tag="KRL22_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBH1271676.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            16816..17100
                     /gene="minE"
                     /locus_tag="KRL22_001175"
     CDS             16816..17100
                     /gene="minE"
                     /locus_tag="KRL22_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBH1271677.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            17185..18315
                     /gene="rodA"
                     /locus_tag="KRL22_001176"
     CDS             17185..18315
                     /gene="rodA"
                     /locus_tag="KRL22_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HBH1271678.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            18356..18769
                     /locus_tag="KRL22_001177"
     CDS             18356..18769
                     /locus_tag="KRL22_001177"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBH1271679.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            19254..19583
                     /locus_tag="KRL22_001178"
     CDS             19254..19583
                     /locus_tag="KRL22_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1271680.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            19587..20378
                     /locus_tag="KRL22_001179"
     CDS             19587..20378
                     /locus_tag="KRL22_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271681.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            20942..22024
                     /locus_tag="KRL22_001180"
     CDS             20942..22024
                     /locus_tag="KRL22_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH1271682.1"
                     /translation="MKKIRKLATKLLIATMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEVVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQQGAILDEVYGNNLRPKIEMYEGVPCSLINSSINTIKFTSKNSNLDPS
                     KHTVTVIGFMNTPYGMVALAPDGVPDEYPFEYDKPFSLDFTGKNLSAAELSKKCKENN
                     VIIKVEIGETASNSGRGMVAYARYVN"
     gene            complement(22236..23429)
                     /locus_tag="KRL22_001181"
     CDS             complement(22236..23429)
                     /locus_tag="KRL22_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBH1271683.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            23748..25592
                     /locus_tag="KRL22_001182"
     CDS             23748..25592
                     /locus_tag="KRL22_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HBH1271684.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            25594..26295
                     /locus_tag="KRL22_001183"
     CDS             25594..26295
                     /locus_tag="KRL22_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HBH1271685.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            26313..27734
                     /locus_tag="KRL22_001184"
     CDS             26313..27734
                     /locus_tag="KRL22_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HBH1271686.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            27835..28146
                     /gene="rplU"
                     /locus_tag="KRL22_001185"
     CDS             27835..28146
                     /gene="rplU"
                     /locus_tag="KRL22_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBH1271687.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            28161..28478
                     /locus_tag="KRL22_001186"
     CDS             28161..28478
                     /locus_tag="KRL22_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBH1271688.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVGEIKREYPKNIKI
                     LKK"
     gene            28492..28782
                     /gene="rpmA"
                     /locus_tag="KRL22_001187"
     CDS             28492..28782
                     /gene="rpmA"
                     /locus_tag="KRL22_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBH1271689.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            28893..30170
                     /gene="obgE"
                     /locus_tag="KRL22_001188"
     CDS             28893..30170
                     /gene="obgE"
                     /locus_tag="KRL22_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBH1271690.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            30222..30590
                     /locus_tag="KRL22_001189"
     CDS             30222..30590
                     /locus_tag="KRL22_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HBH1271691.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTENFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     regulatory      30682..30788
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            30891..32096
                     /locus_tag="KRL22_001190"
     CDS             30891..32096
                     /locus_tag="KRL22_001190"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH1271692.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     gene            complement(32297..32863)
                     /locus_tag="KRL22_001191"
     CDS             complement(32297..32863)
                     /locus_tag="KRL22_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1271693.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKYLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(33143..34402)
                     /locus_tag="KRL22_001192"
     CDS             complement(33143..34402)
                     /locus_tag="KRL22_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HBH1271694.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            34527..35240
                     /locus_tag="KRL22_001193"
     CDS             34527..35240
                     /locus_tag="KRL22_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH1271695.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            35358..36632
                     /gene="larA"
                     /locus_tag="KRL22_001194"
     CDS             35358..36632
                     /gene="larA"
                     /locus_tag="KRL22_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HBH1271696.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            36649..37437
                     /locus_tag="KRL22_001195"
     CDS             36649..37437
                     /locus_tag="KRL22_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1271697.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            37451..38671
                     /locus_tag="KRL22_001196"
     CDS             37451..38671
                     /locus_tag="KRL22_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBH1271698.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            38682..40073
                     /locus_tag="KRL22_001197"
     CDS             38682..40073
                     /locus_tag="KRL22_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBH1271699.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(40336..41616)
                     /locus_tag="KRL22_001198"
     CDS             complement(40336..41616)
                     /locus_tag="KRL22_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBH1271700.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNLAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLYELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSSISFSLDDTIFKTLISY
                     DIKATNIYNLIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            42079..43275
                     /locus_tag="KRL22_001199"
     CDS             42079..43275
                     /locus_tag="KRL22_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBH1271701.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            43368..43892
                     /locus_tag="KRL22_001200"
     CDS             43368..43892
                     /locus_tag="KRL22_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBH1271702.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            43917..44093
                     /gene="rpmF"
                     /locus_tag="KRL22_001201"
     CDS             43917..44093
                     /gene="rpmF"
                     /locus_tag="KRL22_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBH1271703.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            44300..44857
                     /gene="fapR"
                     /locus_tag="KRL22_001202"
     CDS             44300..44857
                     /gene="fapR"
                     /locus_tag="KRL22_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HBH1271704.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            44868..45890
                     /gene="plsX"
                     /locus_tag="KRL22_001203"
     CDS             44868..45890
                     /gene="plsX"
                     /locus_tag="KRL22_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBH1271705.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            45916..46902
                     /locus_tag="KRL22_001204"
     CDS             45916..46902
                     /locus_tag="KRL22_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBH1271706.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            47011..47940
                     /gene="fabK"
                     /locus_tag="KRL22_001205"
     CDS             47011..47940
                     /gene="fabK"
                     /locus_tag="KRL22_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HBH1271707.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            47956..48906
                     /gene="fabD"
                     /locus_tag="KRL22_001206"
     CDS             47956..48906
                     /gene="fabD"
                     /locus_tag="KRL22_001206"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBH1271708.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAVLGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKSNVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            48906..49655
                     /gene="fabG"
                     /locus_tag="KRL22_001207"
     CDS             48906..49655
                     /gene="fabG"
                     /locus_tag="KRL22_001207"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBH1271709.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            49709..49933
                     /gene="acpP"
                     /locus_tag="KRL22_001208"
     CDS             49709..49933
                     /gene="acpP"
                     /locus_tag="KRL22_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH1271710.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            49962..51200
                     /gene="fabF"
                     /locus_tag="KRL22_001209"
     CDS             49962..51200
                     /gene="fabF"
                     /locus_tag="KRL22_001209"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBH1271711.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            51426..53144
                     /locus_tag="KRL22_001210"
     CDS             51426..53144
                     /locus_tag="KRL22_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1271712.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            53175..55175
                     /locus_tag="KRL22_001211"
     CDS             53175..55175
                     /locus_tag="KRL22_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1271713.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
BASE COUNT        21630 a         6109 c        10476 g        17027 t
ORIGIN      
        1 aaaaattgga gagtgatttc aaaatgaagt ttaatttttg tcataacaat ttcaatgtta
       61 ctaatttaga aaaaagttta gatttttata aaaaagcttt agggcttaaa gaggtaaagc
      121 gcaaggaagc agaagatgga agttttatat tagtttattt aggagatggc attactagtc
      181 atacattaga attaacttgg cttagagatt gggatagacc atataattta ggagacaatg
      241 aatttcatct ggctttagaa gttgaggagt ttgatgaggc aaaaaaactt cataaagatt
      301 tagattgcat atgttttgaa aatgaaagta tgggaattta ttttatagcg gacccagata
      361 attattggat tgaaatactt cctaaaaatc actaatttta aggatatgtt tataatttct
      421 ttacaattaa taagaaaata agttatcatt aaattgtagg gactaaaaat ggataataat
      481 gttatgaatt tatgactata aaaatttgtt ggggggagtg atagtagtga aaaaagctat
      541 agcagcttta ggaattgggg cagtagcagt atctgttagc tccataaatg caagtgctct
      601 tgaaaaggga acagtaacag caagtgcctt gaatataaga agtggaccaa gttctgattg
      661 cgataaggta gcaaaattat acaagggaaa aactgtagag attttagaaa agtctaatgg
      721 atggtataaa gtaagggtat cgagttctgt tgttggatgg ggaagtgcaa aatacatatc
      781 aacaagtggt tcgtctgaag gtacatcaag tcaaaataat tcaacttcaa gtgggacaac
      841 tattagtgga aatggtaaag taaatgtgag ttctagactg aatgtaagaa gtggtgcagg
      901 tactaactat tcattagttg gtaaagcaaa taatggagat gtagtaaagt tactagaaca
      961 aagcaatgga tggtataaaa taaaactatc aaatggagtt actggatggg ctagtagcca
     1021 atatatttct aaaacatcag aggatgttgg aacgaataat tctagtaatt caaatagtac
     1081 taataattct gataaaaaac catctagcga agaatcaatt gaaggcaaga atggtaaggt
     1141 aacatctgct gtgagtttaa atgtaagaag tggtcctggg acaagctatt ctataatagg
     1201 aaaattaaat ggtggagatg ttgttgaatt aaaagctaaa agtaatggtt ggtataaggt
     1261 aaagttatcg agtggaacaa ttggatgggt gagtgccagt tatatttctg agactaatga
     1321 ggatacaaaa gaaaaaccaa attcatcatc taaccaaaat tctcaatcta atagtaactc
     1381 aaagccatca tttactggaa attcagataa atctacagca aaaggttcaa caatcgtaga
     1441 ttttgcatat actcttattg gaataccata tcaatgggga gcttcaggac ctgataaatt
     1501 tgactgttct ggatttacac agtatgtttt taaacattct gtaggcgttt ctattcctag
     1561 agtttctaga gaacaggcta attttggaag tgcaatttct atgggaaatt atgcaccagg
     1621 agatttagtt tattttgaca ctgatggtga tggaacaact aatcatgtag gtatatacgt
     1681 aggaaatagt aaatttatcc attgtagtgg tactcagact aatcctaata aggttaaagt
     1741 ggataattta actagttcat attggtctaa agtattactt ggtgcaagaa gatttgttta
     1801 gtaagtacaa tttcttatta aaaaattaga agaaataatt atttatattc ataaattgtg
     1861 actcttaaaa atatacttta ttaataatat aattttggga gggacaaact aatgaataga
     1921 agaaaaacga tatacagagg atttaataat aatagacata agattgattt acgtaaatat
     1981 gttataacga ttgcttgctt gtgtctaatt ggctattatt cttatacaaa aataaaagat
     2041 agcaagatat tggagtatgt atcggctaaa ataccatttc taaataattc atcagatata
     2101 acttataaag atatatctga tgaattaaat tcaataaaaa aagggaaaaa atctaaatca
     2161 caaaccaatt cagatgataa acaagaaact aatccagaaa aagcggtaaa taacactaaa
     2221 gagccagaag aagtcaaatt agctactata gaaggctggg atatgtatac tattcaagtt
     2281 gctgcaatag ataataatga tgatttgaaa aaaatacaga catcattagt taataatgac
     2341 ataccttttt cagttatgga gaaggatgga gtaaaaaaaa tacaaaccta ttcctctttt
     2401 gatgaaaatg atgttagaaa gcagataagc agtgtaagaa aggtgtttcc agatgcattt
     2461 ttatcacact tagatgcacc tatgttgtct ttagagtata caagtaacta cgcttatata
     2521 gagagtatat ctaaagaatt aaataaatta ataacaaact ttaaagaaga atcaagtttt
     2581 tggtcgaatg ctgaaaataa tgtagatatg gaaaaatata atactatttt gacaaataga
     2641 aaggcaatat cacaaaatat atcaaaagaa gctgaaaaga ttgactattc tgaaatgcgt
     2701 ttatttaaag ataatttaat agagtatgta aagaatgtga atgaaaaaat tgatacagct
     2761 tcaaaagcag caaatgaaga aaaatatagt gtaagtaaaa gtctgctttt atcatccatg
     2821 caggagtact ctatgtttat aaattctata aaataaaata cagaaaattt ggactttaga
     2881 aagctatatg aaaaggattg tttaattaag caatcctttt cctcggtttg acttaatata
     2941 gaggtattga tttataaaat aaattataaa aatacggata tttttttaac aattgttaag
     3001 attttttaat atatatagta tacttataga aggcagaaaa aatgtttttt tatagataag
     3061 ggggtaaaac aatgaaactc ttaactttta agggagggat acatcctcca tatagaaaag
     3121 agtactctaa cacaaaggca cttgaaaaag ctcaagctcc aaagatagtt tacattcctc
     3181 ttcagcaaca tataggggca ccagctaaac ctattgttga agttggtgat gaagtaaagt
     3241 ttgggcaaaa aataggtgaa caacaaggtt ttgtttcatg taacgttcat tcttcagtat
     3301 caggtaaagt tattgctatt gaacaacatg aagtaccagg aggttcagct caatgtgtag
     3361 ttatcgaaaa tgactttaag gaagaattac atgagagtgt tcaaccaaaa ggtcagttag
     3421 aggatttgag caaagaagat atagtaggta tcataaaaga ggcaggaata gtaggtatgg
     3481 gtggagctac attccctaac catgtaaaag tatctcctcc accagatagc aaggcagaag
     3541 tagttatatt aaatggtgca gaatgtgaac catacttaac tgcagaccac agattaatgg
     3601 ttgaaaatcc agaagatgtt gtgtttggtt taagagcatt aatgaaggta ttagatgtca
     3661 aaaaaggatt tataggaatt gaaacgaata aaccagatgc tatagaagca attcaaaatg
     3721 tagctaaaga ctatagcgaa atcgaagttg ttggccttca agtgaaatat ccacaaggag
     3781 cagagaaaca acttatttat gcgtgtacag gcaaagaagt tccatctggt ggattaccaa
     3841 tagcagcagg tgcagttgtt gacaacgttg ccacagcagc acagatagct aagtctatta
     3901 aaacaggtat gcctttggtt gaaagaatca ctacaataac aggtagttgc atcaaagagc
     3961 caaagaacct aataacaaaa gttggaacat tagtttcaga aataatagaa caatgtggtg
     4021 gatttaaaga agataagaag attggtaagg ttataatggg tggacctatg atgggaatag
     4081 ctcaatatac tactgaaata gctactaaca aaggttcttc aggaatttta tgtttggatg
     4141 aggaagaatc acgtactcca gatattcaaa actgtttaag atgtggaaga tgtacagatg
     4201 tatgtccatc attcttacaa ccacttttca taagtgcata ttctttaaaa gatgactatg
     4261 acacagctga atatcataga gcaatggatt gtatagaatg cgggtcttgc tcatttattt
     4321 gtccagcaag aagaccatta cttcaatcta taagatcagc aaagagagaa ataggagcaa
     4381 agagaagaaa gcaagctgct cagaaataaa gaaagttaag ggggaaaaac gatggaaaat
     4441 aagttgatag tatcatcttc tcctcatgtg agaagtaatg aagatacttc atatataatg
     4501 aaacaagtta ttatagcact ccttccagca gcagtagcag gagtatactt ctttagactt
     4561 aatgctttga gtgctatgtt tttttgtata cttggtacag taggtactga atttttatat
     4621 caaaaattta cgaagcaaaa aagtactata ggagattttt cagctgttgt aacaggatta
     4681 ttattagcat ttaacgtacc agcatcactt ccttggtgga tgtgtctagt aggaggaata
     4741 tttgcaatat tagtagttaa aatggtattt ggtggaattg gatgtaactt tgtcaatcca
     4801 gcacttgctg caagagcatt tttattagca tcattcccag tagcaatgac tgcttggact
     4861 caaccaggtg ttaactggat aggtaaaaat ttagatgcag ttactacagc aactccatta
     4921 agctttttga aaaatggagc agcaggactg gcagatcttt ctagcaatgg aattagtctt
     4981 gctgacatga tgatagggaa tattggtgga tgtataggtg agacatcagc aatattatta
     5041 ttattaggtg gagtatacct aatgtataaa ggcataataa attatgttat accagtattt
     5101 tacatagcaa ctgtatttat attaacattc cttttaggtg gatttaatat aactttcgca
     5161 atatatcaac tgtttgctgg aggacttatg ttaggtggat tcttcatgct tacggattat
     5221 acaacttcgc ctatgactaa aaaaggtcaa ataatatacg ctgtattagc tggtcttata
     5281 acaactgtta taagaatgta tggtggatat ccagaaggtg tatcttactc aatactatta
     5341 gtgaactgtc ttgctccact tatagataag tttgttagaa atagagtatt tggggaggtg
     5401 gctaaataat gaacagtatg gtgagattag gtggtacttt acttgctata agtgcaatag
     5461 ctgcattagc tcttggagct actaatcagg ttacagctcc agtaatagaa caaagaaata
     5521 tacaagcaaa taatgaactt agaaaagcag tccttccaga agcaaaagaa tttaaagaaa
     5581 tgaaggaaga tacttacaaa ggccttggag atgatcttat agctgaagtg tatgaaggtt
     5641 tagatggttc tgaagtggtt ggatatactt taaaagctaa accaagtgga tatggtggag
     5701 aaattgaagt tatggtaggt atatcatctg aaggtcaagt tacaggtgtt gacattggta
     5761 atatgtcaga aacagcaggt cttggagcaa aagctaagga tgatgcattt aagggtcaat
     5821 acaaaggaaa aactgctgag cctcttgaag tagcaaaagg aagtacaaca gcagataatc
     5881 aaatattagc aatatcaggt gcaactatta catctacagc agttactaca ggagtaaatg
     5941 ctgctataga tgttttcaat agtgctctta ataaataagg agggttaatt atgaatttag
     6001 ctaaagtatt taaaaatggg ctaatagatg agaacccaac atttgttcaa gttataggta
     6061 tgtgtccaac actagccgtt acaacttcag caataaatgg aattggtatg ggtctttcaa
     6121 cagcagcagt tttaatatgt gcaaatttag ttatatcttt aataagaaaa attacaccag
     6181 ataagataag aatacctata tttatagtag ttatagctac atttgttaca atagtaggta
     6241 tgcttttaaa agcatatgtt cctgctcttg ataaggctct tggtatatat ataccattaa
     6301 tagttgttaa ctgtttaata ttagctcgtg cagaaagttt tgctttcaaa acaggagcta
     6361 tgccttcaat agttgatggt gtaggtcaag gtcttggatt tactgttgca cttacaataa
     6421 taggtgcagt aagagaatta cttggaaatg gtagtttatt tggaatgaca ttatttggag
     6481 catctttcca accagtatta atatttatat taccaccagg tgcattctta acattaggat
     6541 tcttatttgc aggatttaat aaattaagaa gtaaaaaagc atagtggagg tgtaataaat
     6601 gaatttaata cttttatttt taagtatcgt tcttgttaat aacgttataa catctcaatt
     6661 cttgggtata tgtcctttct tgggagtttc taagaaggtt gatacagcag tagggatggg
     6721 agttgcagtt acgttcgttt taactctagc ttcaattata acttatttta tacagatttt
     6781 attagtaaaa actggaactg gattcttaca aacaatagct tttatattgg ttatagcttc
     6841 tatagttcag ttcgttgaaa tggtaattca aaagatgagt ccatctttat atcaagcatt
     6901 aggagtttat ttacctctta taactacaaa ctgtgcagtt cttggtatag ctctagttaa
     6961 tgttcaaaaa agttataatt tagtagaaac aataataaac ggatttggag ccggagctgg
     7021 atttacttta gcaatagtaa tattcgcagg tataagagaa agactagaat tagctgatat
     7081 accagaagca tttaaaggtt tccctataac gcttatatca gcaggtttaa tgtcaatagc
     7141 tttcttagga tttacaggac ttataaagct ataaaaaaga ggggtgaaaa tggtgatact
     7201 tacagctgta ttagttttag gaattatggg cttaatcttc gggatagtac tagattttgc
     7261 atctaaaaag tttgctgtag aagtagacga gagagtggaa gctatactag gagtacttcc
     7321 aggagccaac tgtggaggtt gtggatttcc aggttgtgga ggtcttgcaa atgcgatagt
     7381 tgaaggcaat gcaccagtta atggttgccc tgtaggtgga gcagatgttg gtgcaaaagt
     7441 tggagaaata atgggaataa gtgctgaagc aggtgagaaa caagtagcaa aagttatttg
     7501 taaaggaact tgttcaagtg caaaagataa atatgagtat gaaggaatat cagattgtag
     7561 agcagcaaat gttttaaact caggtgctaa gatgtgtaaa tttggatgtt taggtcttgg
     7621 aacatgtaaa gatgcttgta aatttgatgc tatttctata gttgatggaa tagcagtaat
     7681 agatgaagaa aagtgtgtaa attgtggaaa atgtaaagaa gtttgtccta aggggataat
     7741 aatcacaaaa ccagaaagtc aagaagtagt tgtagagtgt aatagcaaag agtttggtaa
     7801 agctgttaag gaaaaatgta ctgctggatg tattggctgt ggaatgtgtg taaaagcttg
     7861 taaatttgat gcaataatat ttgaagacaa aatagctaag atagacccta ataagtgtgt
     7921 agggtgtatg caatgtgtag caaaatgccc tacaaaagta atatcaggtg acataactaa
     7981 gaaaaagaaa gttactattg accaagaact ttgtgttgga tgtacagtgt gcaaaaaaca
     8041 atgtaagttt gatgcaatag agggagaatt aaaagaaaaa cataaggtag atgcagataa
     8101 atgtgtagga tgccatttat gtatggaaaa atgtccaaag aaagctatta aaattttgta
     8161 atatggacaa aataaggata tggaataatt tccatatctc taatgagtac ataaaacaga
     8221 ggtatggaat aatttccata cctctatttt atgtatattt attctaatgg taataaatat
     8281 aacaatagtg taacaaaaaa ggttcgacat ttctgttgaa ttttttacaa tatagtgata
     8341 gactaaatag gtacaaatta cgtacaaatg aggtgaataa atgaatataa tcttggcatc
     8401 agcctctcca agaaggaaag aaattctaga gaatacgaat gtaagatttg atataattaa
     8461 aaatgaaatt gatgagatta tattggaagg tgaaacacca aaacatttag ttatgagatt
     8521 agcttttgaa aaaagtatgt ctgtagcatc tgaacataat gaagatgttg ttattggagc
     8581 tgatacagtt gttgttttag acaatgctat tttaggaaaa ccaaaagatg agtcttgtgc
     8641 aagagatatg ttaaaaagac tatctggaag agagcatcaa gtcataacag gtattagctt
     8701 aataaacttg tgcgaagata aaaaggtaat tgactatgta atcagcaatg tgaaatttaa
     8761 aacgttatca gagcaggata ttgaggatta tctgaaaact aatgagtcat ttgacaaagc
     8821 aggagcctat ggtatacagg gttatggagc tttgttagtt gaagaaatta gaggagatta
     8881 ttttaatata gttggtcttc caatttcaag gttaggcgac ctattaaaaa aatattttag
     8941 tataaatctt ttttatggag tgtgatttat ctgaaaaagt catttaattc aaccattaag
     9001 gtaaaagaaa tggcaccaga ggaaagaccc agagaaaaga tgcttgccaa aggcgtaaaa
     9061 agcttatcaa atgctgagtt gttggctata cttttaagaa ctggcaacaa gaataaaaat
     9121 gctattgaat tagccaacta tataataaat agagatattc agggtattag acatttagaa
     9181 gatatgacaa tagaggagct gtgtaatata gatggaattg ggttatcaaa atcaacccaa
     9241 attaaagcag ctttagaact aggctctaga gtagctagtt ttaaacctat aaagtataaa
     9301 ataaggaatc cttgggatat acagaggtat tatatggata gcctaaggta tttaaaaaaa
     9361 gaggttttta aagcggttct tttaaacaca aaaaatgaga taatatctga tgtagatgta
     9421 tctataggga ctttaagctc gtcattagtc catccaagag aggtttttaa agaagctata
     9481 agaagaagtg caagtaagat aatagtgatg cataatcacc cttcaggaag tgtagaacca
     9541 tcaagagaag ataaaaatat cacatcaaga cttattaaat gtggagaaat aattggaata
     9601 gaaataatag accatataat tattggagat ggattatact ttagctttaa agaaaatatg
     9661 ataatttgac tttatatgtg ataaaataat aggagaatgt tttaaacatg attcttaata
     9721 gtaggaagga gtaaaatcat ggctaaggaa aaaaagaaag aaaaaaaagg tttttttagt
     9781 tttaataaga tgacaaagga tatgggaata gatttaggga ctgcaaatac attagtttac
     9841 ataaaaggac aaggtattgt tgttagagaa ccatcagttg tcgcaataag agatgatagt
     9901 aaagaggtat tagcagtagg tgaagaagcc aaaaaaatga taggtagaac accaggaaat
     9961 atagtagcta taagacctat gaaagatgga gtaatagctg attttgacat aactcaatca
    10021 atgattagct attttataca aaaagcggct gataaaaaag gtgttgtaag tccaagaata
    10081 gctatatgtg ttccttttgg agttacagaa gtagaaaaga gagctataga agaggctgca
    10141 agacaagcag gagctaaaga tgcattcctt atagaagagc caatggcagc ggctataggg
    10201 gctggattaa aagttgaaga accagaaggt aatatggtag ttgatattgg tggaggtact
    10261 tcagaaatag ctgtaatatc tttaggagga atcgttactg ctaaatctat aagaataggt
    10321 ggagacgaat ttgacgagtc tatagtggct tatgtaaaaa aagaatataa tcttatgata
    10381 ggtgaaagaa ctgctgaaaa tgtaaaaatt aacataggtt ctacatttaa agatgatgaa
    10441 gaaataaata tgcaaataag aggtagagat ttaatctcag gattacctaa aacaatagaa
    10501 atatgctcta cagaagttag agaagcatta aaagaacctg taagttcaat agtagatgca
    10561 ataaaatcta cactagaaag aactccacca gaattagcct cagatataat ggaaaacgga
    10621 ataatgctaa caggaggagg cgctttgctt agaggtcttg ataagcttat tacacaggaa
    10681 actggtatgt ctgtacaaat agcagaaaca cctcttgatt gtgttgcact tggaacaggt
    10741 aaatctgttg aagaccaaga aatctttgaa aaagtattaa tgatgaatac taagaattag
    10801 aagttggtga tggccttgag atttgacaag aacaaaaatg agaaaaaaag gattaatgtt
    10861 aaagtgatag caacgggcgt agttgctatc actttaattg gaattgtggg tatatcaatt
    10921 ggtaaatttt ctagtggtag tccagtaaat ttaggagtag cttcagatgc tattacaagt
    10981 gtaggtaagg gaataaatga tggattttct tttatcaaaa atggttttaa agatgtagca
    11041 aattttaaag ataattctaa aaaggtaaaa aaattagaag aagaaaatga aaaacttaaa
    11101 aaaaatatga tagctttaaa tgccaaacta gataaaacag aatcgctaga agagttaaaa
    11161 aagacactga actttgtaca agaagagtat aaggcgacaa gtatttcagc aagtgttgtt
    11221 ggtaaaaatg atggaaactg gtatgagagt tttgtcatag gtgcaggaaa aaattcaggt
    11281 gtaaaaaaag aaagtatagt tatgaatggt agtggattag ttggcatagt ttatgaagtt
    11341 tccaacaatt atagtaaggc aatttcacta ttggattcta aggcatctgt aagctttaaa
    11401 ctagcaaagg atgccaatgc taaaggtaca attactcaaa atactacttt agataataaa
    11461 gatagttata atagtaaagg atatttgcaa ggatatatgt ttgactcatc atataatgta
    11521 attcaaggag atataataac aacatcaggt cttggattct tcccagatgg tataccaatt
    11581 ggcgaagttg aaaaagtggt tgatgataaa gataagtcat taaaatatgt agttgtaaaa
    11641 ccttatgttg attttaagaa tataaatgac gttgtagtca tagaaccaag aaatatagga
    11701 taaaggggat aaaaacaatg aaaaaagttt tactttgtct gttggggatt gtgcttatga
    11761 ctatagaaaa tagtataaca aattatatag atatttttgg cataagcttt aatttagttc
    11821 ttatatatgt aaccataatc tctctttatt tagatgaatt agaaggtggg attatagcag
    11881 taataatagg gcttattaaa gacataaccg ttggtggaat ttttggtgta aatgcattaa
    11941 ttttgtttat tattgcatat gcaattggat acatgagaga tcagctatat aaaggtagtt
    12001 atattattac tttcgtttta atttttatag gcagtttaat tgattcaatt gtcaatatag
    12061 gtacatctag tataatttat caaagctaca acatatcaac actttttgta aaaggtctac
    12121 tagtagcacc aatagtgaat agtttaattg gtttagtaat atatcgctta tctaaaagag
    12181 cagttttaaa acttaaagaa gattagttgg tgatttcatg gaagaaaata aacaagttga
    12241 tagactaaaa ataattaaga tagtcatggg cgtgatattt ttagctattt tagtaaaaat
    12301 aatctatatg actacattta aatatgaata ttacaatgag ttagctgaga ataaaacata
    12361 taaaaagttg gcaatagaag ctccaagagg agaaataaaa gatagatatg gaagactgtt
    12421 ggcaggaaat aaaaacttat ttactgttca agtttcaggt aacgatatta ataagaaaga
    12481 tgcaaataag cattcaagag caaatgaaat atcattaaaa cttataaatt tgctggagag
    12541 aaatggtgaa gaatatgtag atgagtttcc tatatatgta gaaaatggaa agtactatta
    12601 tacatatgac agagatatta gggaatataa atcagaaaat ggtattccaa atgattataa
    12661 tgctaaggaa agtttttatt acttggtgga caaacttata tcagctggaa tattatctca
    12721 agaagataaa agattggatg cgacaagatt acaggcaaaa ctaaatgaaa atggatatta
    12781 tccacctatt ttagttagta aatggatgtt cacagcagaa agagataaga gagattggtt
    12841 ggctagttat aagataaaag aaactaaact gagtgccaaa gaagcgtttg aaaaagtaag
    12901 aaatagtgat gcattagaaa ttgataaaag tttgagtgat gaagatgcaa gaaaaataat
    12961 ggtcgtaagg gatttgataa aatcaaaagg atattctcaa tataatccag taactattgc
    13021 taaggatgtg ggagaaacta cgattgctca aattgaagaa agtgctatgg accttgttgg
    13081 tgtttcaata gcagtagaac cagtaagata ttatcctaat gggtcattag cttctcatat
    13141 gttaggatat gtaggaaaaa tgccatccac tcaaatagaa tcataccttc aaaaaggtta
    13201 tgaaactgga gatatggtag gtcttgcagg agtagaaaag agtaatgaaa gtagattaag
    13261 aggaactgat ggttataaaa tggttaaagt tgatgcattg ggtagaatta gtaaagaaat
    13321 tgaatctaaa aaacctaaat caggagatac tgtgtatctt acactagata aagatttaca
    13381 agaagtttca gataatgcat taaaacagat aatcgaagtt gcttctaaag gaggtacttt
    13441 taaaagtaaa tttggggaca aaccaattag tgcatatgca ggaaaagcac agtcagcagc
    13501 tcttatagct attgatgtta aaaatggaga agtattagct tcatcaagtt atcctaatta
    13561 tgacccaaat aaatttgcaa aaggtatttc tacagaggat tataaagcac ttcaaccaaa
    13621 aaatccaaat gacttactag caggaagtcc acttttaaac ttggttacac aaggggaatt
    13681 tcagccaggt tcttcattta agatggtaac ttcaatggca gcgttagaaa atggtctgga
    13741 tccaaacttt actataaatg accctggggt tataatgtta ggtaaaaaat cttttggtga
    13801 ctatgtatgg aaccatggta gaggaaacca tggtatgaca aatttatata aagcaataca
    13861 agagtcttgt aatatatata tggcaacaat tggtacaggt aaaacatggc cagatggaaa
    13921 aagcattggt atagatatga atgcaaataa aatacttgag tatgcaaaat tatttgggct
    13981 tgaccaaaat acagggcttc aagatgaagt agaagaaaga gcaggtaaag ttcctagcac
    14041 agaagataaa ttgaaatcaa cacaagctct tctaaagtca aatttagaaa gagaaatggc
    14101 aaatgatttt gttgatataa ctagagaaaa aaatcctaaa gaatatgaga aaagaatcaa
    14161 tgagattgta agctgggcag cagaaaagaa aactcctggt agagttgaaa caatgaatag
    14221 gctaaaaaaa ttggatgtta aagaagatag aattgaagaa gtagcagatt tagcagtatt
    14281 cagttatttt aactttgcaa aatggagtac tgcagataca ttcaacttag ctataggaca
    14341 aggtgagaat gcctatacac cagctcaaat atcaagatat gtagctgcta tagcaaatgg
    14401 aggtaattta gtagaattat ctgtagttga tagagctgtt tcaagtgatt attcatcagt
    14461 taaaattaat gaccagaaga aagtcgaaaa aatacctttt aaaaatccag ataacttaaa
    14521 agaattaaca aaaggtatga aattggttgc aagacaaggt acagcgaaga gtgcttttgc
    14581 tgattttcca atagatgtag cagcaaaaac tggtacagct gagaaaagtg ggaaaatacc
    14641 tacagataac gagtatgaat atttaaaaag tcatatgtca tcttataatg tcaacctaaa
    14701 tgatgcgatt aaactagctg ataagatgaa agcagaaaaa gaaaaagagc tttcattagc
    14761 taaggaaaag gaaataaaaa agaaattaga aaataaagat ttgaaagacg aagaaagaaa
    14821 gaaattagag gaagaattag aagatggagt aaaagttaga ttagaggaca ctgataaggt
    14881 gaattcttca tatctaagaa aagctataaa agaattaaat ccaaaaataa cagatgacca
    14941 aatagataga tttaaacaag attatggttc ttttacgtgg actgttgctt ttgctccagc
    15001 agatgaccca gaaatagctg ttgtatgtgt aattcctcaa ggtgattcaa gtgtattctc
    15061 acttttacca actagagaag ttattggaac ttatatggga ttagagccaa ctaatagtaa
    15121 aaatgacaac aagacgaatg atgttaacaa ttcttctgac gaaaatataa atttcgagtc
    15181 acaaattaat agatagctca atctatgtat aaactttagc tttatataga aaaaataaaa
    15241 gggtttaaag cgtatttgaa gaatataaat gatatatcac tctggaggtt gttatgtctt
    15301 taagagaaat ttgtagtcaa gaactagtag agttcaaggg taataaaaga gggataatag
    15361 taaatataaa aagagaagct ccatttgagg aaatacagga aaaaataata aacaaattgg
    15421 aagcatatgt tggctttttt aatggggcta aaattagtaa aattaatagt gattgtttaa
    15481 ctgacatgga gattctagaa cttaaagaag gaattacttc tagatttgat gtggaatttg
    15541 ttgaagatca aaaaattgaa gaaaatagta attttccaac aaaatatgtc aataccctaa
    15601 gatctggtga aaatattgaa tttgaaggtg atgtagttat attgaatgat atgaaacctg
    15661 gttcaaaagt cctttcaaaa tcaaatacag ttgttatggg agatataaat gctggtgcta
    15721 aggttgtagc aggaggtaat gtttttgtaa tgggtaaaat agaaggtttt gtacatgcag
    15781 gtgcagaagg caatgaattt gcatatgttg ttgctggaaa tcttaatcct aaaatattac
    15841 aaatagcaga taatattgca gaagctccag atgatgaaga aaattatgaa agtgaatcag
    15901 aaattagccc agaaatagcc tttgtaagta atggaagaat tgtaatcgaa agctatttgt
    15961 caaagttaga caaatagaaa gaaaaatagg gggtagtatt atgagcgaag ttatagttat
    16021 aacatctggt aaaggtgggg ttggaaaaac tactaccgca gcaaacttag gaactgcgct
    16081 aagcctagaa aataaaaaaa cagtagttgt ggatgcagat attggactta gaaacttaga
    16141 tgtagtaatg ggtcttgaaa atcgaatagt ttatgacata gtagatgtag ttgaaggaac
    16201 ttgtaggctt aagcaagctc taataaaaga caaaagattt gataatctat atttattacc
    16261 agcagcacaa actagagata aaaatgctgt ctcagttgag cagatgattg acctgtgtga
    16321 gaaactaaaa gaatctttcg agtatataat aatagattgt ccagcaggta ttgagcaagg
    16381 ctttaaaaat gcagtagctg gggcagatag agctattgta gttactaatc cagaaatatc
    16441 agcagtaaga gatgctgata gaataatagg tctattagaa gcaaatgaaa taaaagagat
    16501 aagattagtt ataaatagaa ttagaaatga tatggttaag cgtggagaca tgatggataa
    16561 acaagatata atagaaatat tagcaataga tttgttaggt cttgttcctg atgatgaaag
    16621 cataattata tcaacaaata aaggagagcc agctatactt gattctaagt cacttgctgg
    16681 tcaagcatac aaaaatatcg caaaaaggat actaaatgaa gaagttcctc tacttgatct
    16741 tgaagttgaa gatggattct ttggtagact taaaaaaatg tttagcatgg ctaagtagca
    16801 aaggaggata catctgtgtt agatttattt agagtttttt ctaacgaggc taaaactagt
    16861 aaatctgttg ctaaagagag gttaaagcta gttttagttc atgatagagt agattgttca
    16921 ccacaacttt tagagatgat aaaaacagac attttaaaag taatagctaa ttatgcagaa
    16981 atagaagatg atggtcttga aataaaaatg tctaaatgca gaggtgagca tgatgacaaa
    17041 cctgtatctg cattagttgc taatatacca ctaaagaata taaaagatag atgtatgtaa
    17101 ttagtgctta aaagggggat atccttattg gtatatgccc cttttattta attatatgtt
    17161 taaagataga aagacggtga ttctttgaaa aaaatcaata ttaattataa gtcgacaatt
    17221 aagttgataa aacagttaga ctggaaactt atagttacag tattagctat ctttattttt
    17281 gggcttgtta tacttagtag tgcaacacat gctaattcaa caggttcata taatcaattg
    17341 attaaacaag gattagcttt tgtacttggt ataggaatga ttatagtcat attatttttt
    17401 gactataacc ttctaggcag gtattataaa gcgctttata taataagtct tattttgtta
    17461 gccatagttt tattacctgg aattgggaca gtaaaaggtg gagctaggtc gtggattaac
    17521 ttaggaccac ttgacttgca gacatctgaa atagtcaaat taacatttgt actaagttat
    17581 gcaaagatac ttgaatccaa aaaggataaa ttaaatacgt taaaggaagt tatgcctgtt
    17641 gtagtttatt ctcttccatt tatcggatta ttgattgcac aaccagactt gggaacagga
    17701 attgtatttt gttgtatgat atttgcaatg ctgttcacag caggtcttag ttcaaagttg
    17761 ataaaaagag gaataatcat actattagtg tcaatgccac tgatgtattt aatgatggca
    17821 gaccatcaaa aggtaagaat agaagctttt ctaaatccag aagatgtaac tctaaaagga
    17881 aactatcaag ttatgcaatc tctgattgca attggttctg gaggcgtaac tggtaaagga
    17941 ctttacaatg gaagtcaaaa tcaagaagat tttttacctg tacaagatag tgattttata
    18001 tttgctgttg taggtgaaga acttggtgta ataggaatgg cagtgttgat aatcttattt
    18061 atgatattcc tattaaggct tttagcaatt gcaagagatg caaaagattt ttatggaacc
    18121 ctcatagtgg ttggtgttat gggaatgttt ggttaccaga taatccaaaa tataggtatg
    18181 acggttgcgt taataccagt aactggagta acattacctt ttgtaagtta tggaggaagt
    18241 tcgttattga catctttagc aaacttagga ttagtactaa atgtgtgtat gagaagaaag
    18301 aaaataaatt tctaaattta aatacatcta aacataaatt gaggagatta gatatatgaa
    18361 tatagcatta gtagcacatg accaaatgaa aaacactatg gtcggatttt gtataggtta
    18421 tgaatcaatt ttaaaaaagt atggactata tgcaactgga actacaggaa aaagaataat
    18481 ggatgaaact gaattaaata taaatagatt agcatctggt cctttaggtg gagaccaaca
    18541 aataggttct ttaatagtaa cacaagaaat agatttagtt atttttttaa gagacccatt
    18601 gacatctcag gctcatgaaa cagatataca agcgttaata agactttgtg atgtttatca
    18661 tgttccaata gctacaaatc tagcttcagc agaaatattt ataaaagctc ttgatagagg
    18721 agaactatca tggagagaag ttagaaaaag caaaagtcaa cgtatttaaa aaatattaat
    18781 attacagtct aaagaaacag atatataagt gtttaatgcc ctagtctttc tgttgcaata
    18841 aacctagtac ctgtagaaat cttatgaaag atttaaatga tgaagagcta aatttgagat
    18901 taaataatta ggaaatagat tatagataga gtagtagaat ttaaactatt actctatttt
    18961 aataatatga aatagaatca agtctattat tatatatatt taaacttata ggtaatacta
    19021 tttcaaccaa gtaaatattg ttatgacaac attaataaaa caaaaattta tttttaaaat
    19081 ttgataaata gctgtatatt agtatttata gattaaatat taatatacag ctatttatta
    19141 tttttaagtc tattgtagaa tataaacctt gcaatataga gtactatgta ttattatagt
    19201 aaatataagt actatacatt atagagtagt aggtgaaaag gcggtggtac ataatgcagt
    19261 taaataaaga agtgttaaaa ggttatatcg atatattaat tgtttctata ttagaaaaga
    19321 aagattgtta tggatatgaa attgcaaagc aagtaagaga aagaagtgag tttgaattaa
    19381 aagaaggaac aatgtatctt gcacttaaaa gaatggaatc taaaaattta attaaatctt
    19441 attatagcaa tgaacaaagt tcaggtggaa gaagaaaata ttataattta actaatgaag
    19501 gtaaagattt tctagaaata aagaaacaag aatggagatt tattaaaaag gttatgaatc
    19561 aatttttggg agaggtggat taatttatga aactaataga tgaatattta gataaactat
    19621 ataaaaaatg tgacaataaa agtactatag aattaaaaca ggaaatgaga tgccatctta
    19681 tagaatctgc aaatgaattt aaattagaag gattagatga agaagaagca tgtaaaaaag
    19741 caattgaaag atttgatgat ggtgatgaaa tgcagtatga attatgtaat ataataaaag
    19801 aactatcttt atcattggat aggcataaat caattgtaat ggggtttaaa aaagtattag
    19861 gttacataag tataattgca tttttaattt ctggatttat gtggtattac aataatagtt
    19921 tacaacataa tatgtataat ttaggaaaag aacttgatgg agaaataaag caattggcag
    19981 aaagacatga tatgacaaag attggtgaat ataagttaga acttgaaaaa atacttgata
    20041 aagataagta tagtaaagtc aaagctctta gactatatgt aatagatatg aaagatggaa
    20101 acactaattt aagttcttct ggattgaatg ctaatatggt atatgagagg gaagcagatt
    20161 ataataacat aagtaatttt atacagcatt taggatataa tggaaaagat tttttagaca
    20221 agaatgggaa tatagtaaat ccagatattt tcttagaata tttcttttat tttgaatcgg
    20281 agatgttaat tccagtagca tttgcatttg gattattatg tataatagcg tattttatat
    20341 taagatttaa aatttcttta ataaaaaata ataattaaat aattcaccaa ataatcttaa
    20401 tttgtagagt aaataagatg tttcaaaata aaatttgaat catcttattt tttattgttt
    20461 gttatactct tttcttttat atttctccat agtggattgt atctatacat aatcacatat
    20521 tttgatataa ttatactttc caaaaaatgt attgaatata caaattataa tctgtataat
    20581 gttgttaggg gagaatgtat gaagtgtata caattttaat tttaaatgta ttattgacaa
    20641 ttctcctcac tctcgccatt accaataatt ggaaaattga tatacctgtt acagaccaac
    20701 atttttgaat atattaatta ttatcatttt attgtgatga tatcaaaaat gcaggtttgt
    20761 gagttggatt gtatacgaac tatataggaa atatagaaca gattttccaa gaaatctaaa
    20821 tattctatga ccacgtgaat tgctatgcat acatgttgat aatccatatt ttaaatctaa
    20881 aatgaactta attaatggta gggaattgaa agtaaaatat attataaagg agaatgctaa
    20941 tatgaaaaaa atcaggaaat tagctactaa actattgatt gcaacgatgg ttttaacctc
    21001 atgtatgagt gtaacagttt atggtatgac agctaaagat gttactgcaa agacaccgaa
    21061 aagttatgta gctggaacca acagtatata tggtccaaag ttatcacaag ctcaacttaa
    21121 ttcggtagca caagcaacag cagactttat gaacaagaaa attacaaaga acatgaccac
    21181 agatgctaag attagggttg cttataatca cattaaaaac aacacaacat atgttaactg
    21241 gaacgcagca gagggagcca atactgctta tacattggtt actaaaaaag gtgcttgttc
    21301 tggaatgtgt aggagcttga aagctttatg tgatgctatg ggaattgaat gttattatgt
    21361 acatagtaca acaaatgacc atcagtggaa tcttattcgt tttgaggatg gacgtttgta
    21421 tcatgtagat attgatgcca acaaatcagc aggagcagac atcatataca agagtcttac
    21481 tcacccatta ccatttgaca agaaagcata tccagctgtt ggcgaagtag taaagacaca
    21541 gaatccaacg ccaactgtta agaaacctac gccagctaag ccttctgcgc cagttggacc
    21601 tgggaatcac actatgatag cagatcaaca aggggcaata cttgatgaag tttatggaaa
    21661 taatctacgt ccaaaaattg aaatgtatga gggagttccg tgtagtttaa tcaactcatc
    21721 aataaataca attaagttta caagcaaaaa ttcaaattta gacccatcaa agcatacagt
    21781 tactgtaata gggtttatga atacaccata tggtatggtt gcattagctc cagatggtgt
    21841 acctgatgag tatccttttg aatatgataa gccattttct ttagatttta ctggtaagaa
    21901 cctttctgca gcagaattat caaaaaagtg taaagaaaat aatgtaatta ttaaagtgga
    21961 aattggtgaa acggcatcta attctggaag agggatggta gcatacgcta gatatgtgaa
    22021 ttaatacaaa tatactagtg tacaaataga acatattata aataatgcac cctcgcacaa
    22081 agggtgcatt tatcattata tcagtcattt tagaaaataa aaaaggagtt gaacttaaaa
    22141 ttagattaga aaaattaatt ttgagacaac tccattttaa tttattttta aatataaaat
    22201 catttatttt aaataatatt atgtgtgatt aatggctatt taactaattt tgcaaattct
    22261 gcaccaaatg ccatacactc ttttaatgtc tcttcactag ggaagaattt tttcttaaga
    22321 gattctacag gcattttgaa tgacatagat ttaagtaaag tctcagccat agttatacct
    22381 tcaccactcc aaccaaatga accaaatact cctgctatct tgccttggtt agccattggg
    22441 tctataacag agaataaatc ccacataggt ttaaccatag tcttgtttat agttggagag
    22501 cctagtaata ttacttttga cactactaat gtatcgtgca tttctgttaa tgtcatatct
    22561 tctaaatcat ataattcagc ctttgcacct tctttatcaa gtccttcttt tatcttttta
    22621 gccatctcta aagtattact ataagctgat aagtagaata tagaaacttg attttgatta
    22681 gttgtattaa cagcttctgt agaccactca acatatcttt taacagcagc cattgggtct
    22741 ttagtaagca ttggaccatg agaagtcaat atagtatcaa attctatgtt tagtcctacc
    22801 accttatcta cagcacttaa aacatgttta gcaaatggct taactataca atcatagtag
    22861 tgtttagctg attttagata atcttcacta ttcactacct ctgcatcaac acttgcaaag
    22921 tgacaaccaa atgcatcaca agttaaaaga gtcttgtcct cctcaatgta agtaaacatt
    22981 gtatcaaccc aatgtaagaa tggagcagtt ataaatctaa gatttctttt accgatattt
    23041 aaaatttcac catcttttat tacatgacag ttaaaaggtc tatttatttg accatctaag
    23101 tatagtttag cagctttagt acaataaact tctatattag gatttatatc taataagtat
    23161 tttaaactac ctgcatggtc tggttctgtg tgatgaatta caacatagtc aattttagct
    23221 atatcagtaa cctctgataa attacttaaa aactcatctt taaaatttgc ctttacagtg
    23281 tcaaataaaa ccgttttttc gtccttgatt aaataagagt tgtaagttgt cccaaactca
    23341 gtttccatta ttatgtcgaa tacttttaaa ccttcatcta ctacgccagt aaagtagata
    23401 tcttttttta cttcaaaaac tttactcatt tttaaccctc ctaaaattta tcattatata
    23461 agtaacatac cccattttga ggtgaatgaa acaaaagatg tcatgataag tcatgtaaaa
    23521 caatagtttt atgtttataa tatatcatac tttgtaaaaa aattgtattt caataaaaat
    23581 ttaatagaaa atattcttaa atatttttag ctattctatt ttgtgaataa tatgtatttt
    23641 aaattcaata ttttagttat atttttgata gaaaatattt tatcgtgtat aatattactt
    23701 ataaataaga ataaaaataa agagcttgtt tggaggaatt ttaataaatg aataaagtag
    23761 acttgaaaaa aatcttaaaa aaagtagaaa agcctgctag atatcttgga aatgaaataa
    23821 attcaattca taaagatact agtaatagtg aattgataag atatgcacat tgctttccag
    23881 atttatatga agttggtatg agtcacttag ggagtcatat attatatgat gtaataaata
    23941 aggatgaaga tgtattttgt gagagagtgt attctcctgc agttgatatg gaaaatataa
    24001 tgagagaaaa aagtatacca ttatttgcat tagagtcaag agagcctata acaaactttg
    24061 attttgtcac ttttacactt caatatgaac tttcatacac taatatctta aatatattag
    24121 atttagccaa tataccaata ttaaaagaag aaagaacttt ggaagaccca tttataatgg
    24181 ttggtggtcc ttgtgcttat aattccgaac cattagcaga ttttgtagat gtagtaatat
    24241 taggtgaagg tgaagaggtt aatttagaag tagtaaatga gtataaagaa tggaagaaaa
    24301 ataaaacgac tagagaagat tttttatata aaatatctag catagaagga gtatacatac
    24361 caagttttta tgatgtcaag tacaatgaag atggtacagt tcaaagtgta actcctaata
    24421 gagaagggat tactaaaaat cctactaaaa ggataataaa agatgttgag actgtagatt
    24481 atccagaaaa actaatagta ccttatatag atactgttca tgatagaata gtactagaat
    24541 tatttagagg atgtactaga ggatgtagat tctgtcaagc aggtatgata tacagaccaa
    24601 taagagaaaa gagtgttaaa agacttaaag aaatattaga taaattagtt aagaatactg
    24661 gatatgatga aatatcatta tcatcactta gtacgagtga ttatagtaag ttatcagagt
    24721 tgactgatta tttggtagat gaatatgcat ctaataatat tgggatttcg cttccatccc
    24781 ttagattaga taatttttca atggaaattg ctgataaaat acaacaagta agaaaatctg
    24841 gacttacttt tgctccagaa gcaggaactc aaagacttag agatgttata aataaaggtg
    24901 ttacagaaga agatttggaa aatgcaacag aaagagcttt tgagatgggg tggaatagtg
    24961 ttaagttgta ttttatgatt ggtttaccaa ctgagactta tgaagattta gatggtatag
    25021 ctaaattagc ttataaagtt attgatattt atagaaaagt aaatggagga aagctaaaga
    25081 gaagttttag tgttacagtg agtacttcta catttgtacc aaagccattt acacctttcc
    25141 aatggcatgg tcaagatact acagaagaag ttattaataa gcagagacat ttagtaaata
    25201 aattaagaaa taacaatata aaatacaatt atcatgattc aaagactagt ttgatggaag
    25261 cagtagtagc tagaggcgat agaagaatag gaaaagttat atatgatgca tttagactag
    25321 gtgctaaatt tgatggatgg gcagaacatt ttaatttaga tatatggaaa gaagctatgg
    25381 aaaagaataa tctttctata gatttttatg cacatagaaa tagaaactat gaagaggtat
    25441 ttccttggga ccatatagat gtaggtatta gtaaaaaatt cttaattaga gaagacgaaa
    25501 atgctaaaaa agaaaaaatc acttctgatt gtagacataa ctgcaatggt tgtggaataa
    25561 atatacatga tataggaagg gggctttgct aatatgagta agataataag agtaaaattt
    25621 aaaaaggaag gcgacatgat atatatatca catcttgacc ttcagagatt gttacaaaga
    25681 gcgtttagaa gagctgaaat aaacttatca cattctcaag gatttaatcc tcaccctaaa
    25741 atgagttatg gcaatgcttt ggctttaggg acagaaagtc aaggtgagta tgtagatatt
    25801 gaaatagaag aagatgattt atcagtagag gaatttttaa ataaagtatc aattcaactt
    25861 ccagatggga tagattttat caaagcaaaa gaaattgata gacaaacacc ttctctttct
    25921 tctgtgatag actatggaga atatttgttt aatatagatt tgaaaagacc tatgacgaaa
    25981 gagtttgtaa aaagaaaagt aattgacttt atgaataata aagaaataat cataacaaaa
    26041 aagaataaaa aaggtaagat ggttgaagta gatataagac ctatgataag aacctttgat
    26101 gttttaaatt tagaagatga acatattact cttactgcta ctatagctac aggctcaaaa
    26161 actaatttaa atactaatat acttatacca aagatattag agatgtttga acttgatatt
    26221 gacccattag atgttgatat attgagaaga gatttatatg tattagaaga tggggaatta
    26281 gtgactccta tgtaagctcg agaggtgaag ttgtgaaaaa gatagttatt gagtccctaa
    26341 tagggtccca gaaaacagca gtacttgaag atgaaagatt aacagaactt tttgttgaag
    26401 acaatttaaa taagaagact gtatccaata tatatcgtgg aatcgtaaaa aaagttatac
    26461 caggaataga agcttgtttt gtagatattg gatttaagaa acttgcttat ttacaattaa
    26521 aaaagggaag tactataaaa tctggtcagg atattttggt tcagataaat aaagaagaaa
    26581 taggaactaa aggcgcaaaa ttaaacactg agattagtat ttctggaagg tatattgtct
    26641 atataccttc caatgataga actacaatat caaataaaat tactgatgaa aaagaacgat
    26701 ttagattaaa aaaaattact aaggcagtaa ataaggaaaa tctaggatta ataataagga
    26761 ctgaggctca aggttgcact catgatgaaa taaagaaaga tatagaagag ttgaaattaa
    26821 agtatgaaaa cattttaaaa gaatataaac ttggtatagg tccgaaatta ttatataagt
    26881 ctttagattt tgcaactaaa tatgtaaaag ataatgtgaa tgatgatatt gaatctataa
    26941 ttaccaatag ttatgataag tactctgaac ttaagtctat tttaagaggt atagataaga
    27001 cttatgttga taaactgtgt cttgaggaaa atagagatgt atttgattta tacagaatag
    27061 aatctaaaat agaaaaatta ttaaataaaa aagtatggtt aaagagtgga ggttatttaa
    27121 taattgaaaa aacagaagct cttacggtta tagatgtaaa tacgggtaag tttattggaa
    27181 ctggtaaact tgatgaaacc gtttataaaa ctaatcttga agctgcaaaa gaaattgtaa
    27241 gacagcttag aattagagac atagctggga taataataat cgattttatt gatatgcata
    27301 aaaagaagca tcaaaaggag attttacaca tcctagaaga agaatttaat aaagataaaa
    27361 gaaaagctga agtattaggt atgacaaaac ttggtttagt agaagttgct aggcgtagag
    27421 aaaaagaatc cattgataag tattatttaa tgtcttgtcc atgttgtgat ggtgaacaaa
    27481 caataaaatc tgtacattat atactagata gtattgaaaa agaaattatg agaataagtg
    27541 aacatactgt ttacaaaaac ataatggtag aatttaatga ttttattttt gaacaaataa
    27601 aagaatatta tatggatata attgataaaa ttggtgaaaa atataatata aagatttctt
    27661 taaacgcaaa tagtacatta aagcacaata aaaccaatgt tattttcgat aaaatagttg
    27721 acaataaaat gtaaatattt tataattaat aattgtaatg ccgcacagta aaggtttaaa
    27781 tcttcaaatg aagtaccttg tactggcgag tttgaggccg aggaggtgta tttaatgtac
    27841 gctatagtaa agactggtgg aaagcaatat aaagtttctg aaggtgatgt attattcgtt
    27901 gaaaaattag aagctaacgc aggtgatgtt gttactttaa acgaagtatt agcttgctct
    27961 aaagatggag aattaaaatt aggttctcca gtagtagaag gagcatctgt tcaagctaaa
    28021 gttgttgaac aaggtaaagc taagaaagtt atagttttca agtataaagc aaaaaaagat
    28081 tacagaagaa aacaaggaca tcgtcaatca tacactaaga tagttgtaga aaaaataaac
    28141 gcttagttat tggttaagtt atgataaaag ttaaatatta ttataatgat gatttcttgt
    28201 tgcaaggttt ttgtttaaag ggacatgctg attttgctga aataggctat gatatagtat
    28261 gtgctgcagt tacatctaat gctattgcag ttataaattc tttagacaaa ttacagaaga
    28321 ttgaatttga aaaagtagta ggagaagaag gtcatataga gtgtatagtc aaagatacac
    28381 atgtaaaaga cgcacaatta ttactaaatc actttcaatt agcggttgga gaaattaaac
    28441 gggaataccc aaaaaatata aaaattttaa aaaagtaggg ggtgactcca tatgttaaac
    28501 atgaatttac aattattagc atctaaaaaa ggggtaggtt cttctaaaaa tggtagagat
    28561 tctatatcta aaagattagg tgttaagaga ttcgatggtc aattagtaac tgctggaagt
    28621 ataatagtta gacaaagagg aactaaaata catccaggaa ctaatgttgg aaaaggtagt
    28681 gatgatactt tatttgcatt agttgatggt actgttaaat tcgaaagaaa agacaagaag
    28741 agaaaaaaag ttagtatata tccagtagca atagctgagt aatatacata aaaggagtgt
    28801 tgaggcactc ctttttctta taatactgat gaatttataa tggtattttt ggtaatgcta
    28861 attaaaagtt tttaattaag taggtgaaga atttgtttat agataaggca agaatatttg
    28921 ttaaggctgg aaatggtgga aatggttcgg tagcatttag aagagaaaaa tacgttccag
    28981 ctggtggtcc agacggtgga gatggtggtc gtggagcaag catcatattt gaagttgatt
    29041 tggggcttag aactctaatg gactttaagt accagaaaaa atatcaagct caaaatggtg
    29101 gcgacggaag caaaggaaaa agagctggta aaaatggaga aaatttagta ttaaaagtac
    29161 cagcaggtac agtaataaga gatgaggcta caggtcttgt attagcagat ttaaaaaaag
    29221 aaggagatac agctatagtt gcaaaaggtg gtataggtgg taaaggtaac caacactttg
    29281 caaatgcagt aagacaagct ccagcttttg caaaatctgg tacagatgga gaagaaagat
    29341 ggataactct tgaacttaaa atgatagcag atgttggtct tttaggattt ccaaatgtag
    29401 gtaaatcaac atttctatca gttgtaacta aggctaaacc aaaaattgca aactatcatt
    29461 ttacaacact tacaccaaat ctaggtgttg ttcaaactaa gtttggagat agttttgtac
    29521 ttgcagatat acctggaatt atagagggtg cttctgaagg cataggatta ggtcatgagt
    29581 tcttaagaca tgttgagaga acaaaggtat tgatacatat tgtagatata tctggattag
    29641 agggaagaga ccctattgaa gattttgaca agataaatga tgagcttaaa ttgtacaatg
    29701 aaaagctttc aaagagacca caagttgtag ttgcaaataa atttgatata ttagaagatg
    29761 agagtaagtt tgagaagttt aagagtgaat tagaaggcag aggatataca gtatttaaaa
    29821 tgtcagcagc aactcgtcaa ggcatagatg aagtaatagc ctatgtttct aaaatgctaa
    29881 aagaagtaga agatgtggag ctagtttcag aagaagaaat gtatagacca gaacttgata
    29941 ttggtactga agaagagtta agtatagata ttgaagatgg tgtgtatgta gttacaggta
    30001 aagcacttag aagaataatg tattctgtaa attttgatga tatggaatcc cttcaatatt
    30061 tccaaaaagc tatggagagt caaggtgttt ttgataggct tagagaaatg ggaatagaag
    30121 atggagatgt ggttaaaatt tatgaattag aatttgagtt ttacaattaa tttaaatata
    30181 gattatagat aatttaatta tagaattata gaggtgagaa tatgttaaaa ggaaaacaaa
    30241 gggcgtattt aagatctttg gcaaatactt taaagcctac tacacaaatt ggtaaagaag
    30301 gtgttacaga gaatttctta gagcaattag atggtatgtt aagaactaga gaattagtaa
    30361 aagttactat attagaaaat gcaggtcttg atactaaaga aactgctaat gcagtatgtg
    30421 aagctttaag agctgaattt gtgcaggcta ttggttttaa atttactatt tacaagagga
    30481 atattgaaga gcctaaaata ctttttccag gacatgaaca ggcgaaagca aagactaaaa
    30541 ataataatgt tacaaaaaag ggtaaaccaa ctaaaagagc tgttagataa tagtttatac
    30601 ccttttaggg aaataagtta aaaaaatagt gacaattgga agaaattgta ttatactatt
    30661 aaacataaat ttaaattagc aatcttatca agagtggcag agggactggc cctgtgaagc
    30721 ccggcaacca gtatatttaa ttatacattg gtgctaaatc ctgcagcatt tatgctgaaa
    30781 gatgagtata aacccgtcat atggcttgag tttatactca agcttttttt attggtatat
    30841 ttatatatat aaataattta atataatcaa aatgatgggg gtatgttaca gtgaagatag
    30901 caatattagg gtatggaaca gtaggaagtg gattaattga tttaatagaa aataatactt
    30961 caaaaagaga tatagaagtt gttggaattt tagttaaaaa taaagaaaaa cacaagtata
    31021 agaagtattt tgataagata actactgata tagaagatat atttgacaag gatattgata
    31081 tactagttga agtaattgga ggattaaatc cagcttttga ttatgtaaca agagcgttaa
    31141 ataaaaaaat acatgtagtg acagctaata aagatttact ggctgaaaaa ggtagtgatc
    31201 ttatagaatt agctaactta aataatgtta gcatcaagtt tgaagcatct gtggcaggtg
    31261 gtattccagt tttaaaacca ttgatagaat cactggaagg caacaatata aagagcataa
    31321 acgctatttt aaatgggact tgtaatttta tattatcaaa gatgtatgat gaaaatttac
    31381 cgtatgatgt cgctttaaaa caggcacaag agttgggatt tgcagaagtt aatccagatg
    31441 cagatgtttt aggatatgat agtgctagaa agttatctat actgtctact ttatcttatg
    31501 gaaaaatagt atattggaaa gatttattat tagaaggaat aacttcaata gatgaaaaag
    31561 atatagaata tgcaaaaaaa ttaaattgta agataaaatt ggttgctaga agtaagtatg
    31621 aatcaggaga agtaagtgga tttgttagac cagcattagt ggacaataat aatatgcttt
    31681 caaagataga taatgagttc aacgtagtta ttttagtagg tgattcagta ggtgaacttt
    31741 cttttgtagg taagggagct ggaagaggtg caacaggaag tgctgtttat gcagatatta
    31801 tagatataat agataataga agttcaaata taaagtcttt ttcaaaaggg aaattggatt
    31861 taagtggact tatagaagat gagtgtagtg cagtagttag atttggtggg tataataata
    31921 aagatggaat tttagaatgt ttagataaat atgtagatag ttatgatatt atagatgatg
    31981 aagaattggc gatttttgta agtgcaaagt cagaacatga gattgataga gttttggaaa
    32041 ttgtaaaaag aaataattac agtgaatcag ctaaaaaatt attgaagata gattaatatg
    32101 tttatgcaag aattatgaaa atttaatagg gtgtctcaaa atagagagat aagccttttt
    32161 tccagtgttg aaataataaa aatatatttg attttataaa aaaagagtgt ctcatgaact
    32221 aaaaagttca ttttgagaca ctctttttta atatctggtg aattaataag ataatagaaa
    32281 aatgtatacg ttataattaa ccaataaaga aattttcact agcttcatta atagcttgct
    32341 gagttaccct tatatatcgc tgtgtagtgg ctacagagct gtgatttaaa agttctttaa
    32401 ccaactctaa attattgtta cttttttcaa attgagtagt agcatagagc tttctaaagc
    32461 tatgtgtact tatattatac agatttaagt atttacaaat tatcctcaac tgtttttgaa
    32521 tagcctttgt ctttatattt actaagtagt catttgattt aagattatac tttcttgcat
    32581 gttcatttat ggactcaatt atatttttat taactggtct atactgtaat ttgcccgtct
    32641 ttttttcatt tatttccaac atattacctt taaaattacc tatctttaat cttaaaatat
    32701 ctgatattct tagacctaaa ttagcttcta acattagtgc caatgcaact ttaggatttt
    32761 ttctaaatct tttttcaacg ccattttcac tataagtaaa gccagtatgt aatagttcca
    32821 ttatcttttt atattcgtct atttctatag gtcttgttgc cattttcaac cactcctctt
    32881 agtttgattt ggtaagttta ggtcggtatt tattatataa tataaatgaa atattatata
    32941 atggaaaaat ttcccagtaa acttatacaa gtgtgatata tgtgattaag gagaattttt
    33001 tgaaaaatat ttctaataaa attattaaat tgtgatgaaa taactatgct gttaaactaa
    33061 ttaaaaaggt tattaaaatt atgacaaata taataaaaaa atggaagtat ttagttaagt
    33121 tttattagtt ttatttttag ttttattttt ttcgtgaaaa tttcttagtg aaaaaagtat
    33181 ttttatatcg cattagtttc ccatttgtag ataaagtttt catatgtttt tttgcaataa
    33241 atacggctga gattagataa attattacta caatttgaag aattgtatca taatagctaa
    33301 gataataaaa ccagattaaa ttattatata taacgttgta tgtatcagca aagctagaaa
    33361 ccaacacagc agagtttgca attggataaa gtataaatat aaagatagca gctaaaactc
    33421 catgcgcaaa tttacttagt atgtataatt ttaaatctat gtccgttttt gatagaaatg
    33481 tacaacattg agctaggatg gataatccac taaatcctat caaaaaacta gctaaagatg
    33541 ctcttaaaat ttctggagaa cttgttatac tagatacttt attgcatcct atagtaattt
    33601 caaatagacc acttacaaat gcttgacaga gttctttact aacacctaaa aatgaaagag
    33661 gcaaatatat aactgatgct attaatgaga ttacattaaa aagagatagt attttaaata
    33721 ctactgaaaa aacaattaca aatccaccaa ctgtaagtaa tgtatttact ccattaaata
    33781 cagcatttcc aaataaaaca aaaaaaccat tcccacttga atttctaatg ttgattacat
    33841 tttttatatt tgtttttaaa tccaattttg tctttggaag attttcatta ccataatttc
    33901 taaagaaaag accaaccaat atagttccta gataatggca gagaatcatt aaataaccta
    33961 agtttgaatt ttggaacata cctgtaccaa ccgaacctat tatgaataaa ggtcctgatg
    34021 tagaacaaaa agacacaagt ctttgtgctt catacttaga aatttgtcca ttactcctaa
    34081 attcagaagc taaacttact cctactggat aaccagatac tgtagatata gcaaaagcta
    34141 aagcgctctt tcctgaaaca ttaaatacaa atctagttat gggattgatg ataaacccta
    34201 taatatccac tatttttaaa tcaacaatta agtttgctcc aattataaat ggtagtagtg
    34261 atggaactaa aacattagac catatagaaa agccttctct tgcagatttt atagcttcat
    34321 ttgggtatag gataatccct aaaactagaa ctccaactat gatagatgga gcaaaaaaag
    34381 caataatttt attttttttc ataatatcac ctgtaaattt gagttataag atattatatt
    34441 aaaagtaata aaaatatatg aatgtaatgg cttaagatat ataatagata tatattacaa
    34501 caacgattat catattggag gaaaaaatgt ttaatagtat agctagtaaa aaagtttatg
    34561 aacaagtaat tgagcaaata caatataaaa tactaaatgg agagttaaaa aagggggata
    34621 aattactatc agaaagagaa ctgtctgaac aaatgaatgt gagtagaact tccataaggg
    34681 aagctattag ggtattagag actatgggag tgatagaaag cagacagggt gaaggaaatt
    34741 ttatatgtac aaatatagaa aaaactttaa tagaaccttt atctatgatt tttaaactta
    34801 ataatggtac acttgaagat atattagagc ttagaataat cctagaaatt gagattgcaa
    34861 aacttgcttc aaagagaata acttcttctg aagttataga attgaaacat ataatagatg
    34921 aaatgagggt agaaactaat aaaaaagata ataatcgagt actggtgtta ttagaccaaa
    34981 aatttcacag taaactagca acattaagta aaaattattt aattcaaagt ctttttatga
    35041 cagcatcaaa attatttgat ggatttatag aagatgcaag agaaaaaata atcgcagaac
    35101 cttttaatga aaatatattg cttaaacagc atgaagctat atacaatgca gttgtagaaa
    35161 atgatgtaga acttgcatgt gagaaagcaa aggaacatat ggattttata agtaaaaatt
    35221 atagaaaaaa tgaaaattaa aagtttgtta taaaataaat tattcttgca aatggtagat
    35281 aatggtacta tcatataaat gtaaaactgg tatgaccaca taccaatttt atagtttatt
    35341 ataatgggag attaaaaatg gtaaagttaa aagtaccgta ttcaaaacaa ggaatgattt
    35401 tagaaatacc tgatgaacgt tttctcggtg ttttggagtc aaaatcggat aattatatag
    35461 aacataagac tcaagaagag atagttgaag aatctatgaa taatcctata ggctctaatt
    35521 ctctggaaga actggttaag gggaaaaaga atgtagtcat aattacaagt gaccatacaa
    35581 gacctgtacc aagtagaata actatgccaa ttatattaag aaggattagg aatgttaatc
    35641 cagaaattga tgtgaagatt atagtggcaa ctggatttca taggccaagt acaagggaag
    35701 agctaattta taaaatggga gaagaaatag tagataatga agatatagtt atgcatatat
    35761 ctactgatga taaatctatg tgtaaagtag ggatattgcc ttcaggtgga gatttatata
    35821 taaacaaact agcatatgag gcagaacttt tgatagcaga aggttttata gaacctcatt
    35881 tctttgcagg tttttcaggt ggcagaaaaa gcgtacttcc aggaatcgca tctgcaaaga
    35941 ctataatgta caatcactgt agtgacttta tagatagtga taattcaaga actggaaaat
    36001 tgaataataa tcctattcat gaggatatgg tatatgcagc taaagttgca aaattagcat
    36061 tcatattgaa tgttgtaata gataaagata aaaaaataat tgcttccttt gctggtgatg
    36121 tcgaaaaagc acatactaaa ggatgtagat ttgtaacaga gttatcaaaa gtaaattcta
    36181 taaaatctga tattgttgta actacaaatg gtggatatcc actagaccaa aatatttatc
    36241 aatctgttaa aggaatgaca gcagctgaag ctacttgtaa agacggtgga gtaataataa
    36301 tgatttcagc atgtaatgat ggtcatggag gtcaatcttt ttatgaaaat gtagcaaatg
    36361 cagattctcc aaaacaactt ttagataaaa ttagaagtgt cgatagagta gatacgattc
    36421 cagaccaatg ggaatttcag atactagcga gaatattatc taaatatact gtgataatgg
    36481 taacagataa gtgtaatcct gaaatgataa aaaaaatgca tatgaaacat gcatttaact
    36541 ttaaagaagc tttagaaatg gcgaatagta tagttggtaa ggagagcaaa gtagtagtta
    36601 tacctgatgg agtatcagtt atagttaaat aaaaaaggag tgtactttat ggaaattttg
    36661 acatgtatta aacaagttcc tggaacgact tcagtagaag ttgatgaaac tacaggagta
    36721 ctaaaaagag atggagtaga ttcaaaaatg aatccctatg acctatatgc tttagaaaca
    36781 gctcttagaa taaaggaaga taagaaagcg aatctaaaag tacttagcat gggtcctcct
    36841 caggcaaaga aggtaattga agaaagtttt atgatgggag ctgatgaagg agcattaata
    36901 agtgatagga gatttggagg agcagatgta ttggctactt cctataccat atcacaaggt
    36961 attaagaaga tgggaaaggt agacctaata atttgtggaa aacaaactac tgatggtgat
    37021 acagcacagg tgggacctga agtagctgaa tttttagata tacctcatgt tactaacgtt
    37081 acaaaattaa ttgaagttaa agatgaaagt atagttgttg aaatagatat gccaaatgat
    37141 ttacaagtat gtgagattga atatccatgt ttaataactg tagaaaaaga catttttcaa
    37201 ccaagactac cttcatttaa attaaaactt aatactaaag atagagaaat acctgtatat
    37261 agcttagatg actttgaaga taaagatgaa aataactatg gacttaacgg ttctcctact
    37321 caagttgtaa gaatatttcc tccaaagcca aatacagata aaaatattgt aagaggaaat
    37381 gcagatgaac taagttttgc acttgtaaat aaattagagg aattaaagtt ggtgtaaggg
    37441 ggagtaataa atgtcaaaga tagttgtaaa tcaagataaa ataactgact taaagagaat
    37501 tttagaaata tgtccttttg gggctataga agaaaagtca ggtatagtag aaataagtgc
    37561 tggctgtaag atgtgcaagt tgtgtgtcaa aagtggacca aaaggcgcat ttgaatttat
    37621 agagagtagt aaagtacaaa ttaataaaga tgaatggagg ggaattgcag tatatgttga
    37681 acatcataat ggaaatatac atcctgtaac gtacgagctt ataggtaaag ctcgtgagat
    37741 ggcatcaaaa ataaaacaac ctgtgtattg tgtatttgta ggaaaagaca taaaagataa
    37801 gtgcagtaat ttgatttctt atggggtgga tgaagtattt gtatatgatg aagatgaatt
    37861 taaagatttt aggatagaac catattcaaa agcaatagaa aactttatag ataaaataaa
    37921 accaacgata gtattagttg gtggaactac attaggtagg tcattagctc caagacttgc
    37981 cgctagattt agaacaggtc ttacagcaga ttgtacaata cttgatattc aatcaaatac
    38041 tgatttagac caaataagac cagcatttgg tggaaatata atggctcata taaacacacc
    38101 taataataga ccacaatttg ccactgtaag atataaaata ttttcagcac cagaaaaaat
    38161 agagaatact acaggaaaga taactttatg taaagtagaa aaaaaagaac taaaatctaa
    38221 aattaaggta ctgagtgtaa aagaaaaaaa taaagaagtt ggtctggaag aagctgaagt
    38281 gatagttgtg gcaagtagag caataaaaaa acaagaagat atggagatga tatataaatt
    38341 agctgataag ctaaacgctc aagtggcagg aacaagacct gtaatagaag caggttggat
    38401 agatgctaaa aaacaaatag gtcttagtgg tagaactgta aaacctaaat tgataataac
    38461 ttgtggtgta tctggagcag ttcaatttgt tgcagggatg cagggtgctg actatatagt
    38521 agcaataaat aaagatgata aagcgcctat acttgatgta gcacatttag ctttaatagg
    38581 tgatatttat gatattattc ctaaattgat tgaaaaaata gaaaataaca aagataataa
    38641 tcaaaaatat atggcatcag cagctaaata gggggataga aatgtataaa ttaatcgata
    38701 aaaaagatat agatttttta atagatactt gtggagaaga aaatgtatta gttggaagtg
    38761 atataaatga agatttttca catgatgaac ttggagggat tgagaagtac cctgaagttt
    38821 tagtaaatgt acttgaaact gaacaagtat ctaaaataat gaaatacgca tataaaaata
    38881 atataccagt cacaccaaga ggtcaaggta ctggtcttgt aggtgctgct gttgccataa
    38941 atggtggaat aatgattaat ctatgtaaaa tgaataaaat acttgaagtt gattatgaaa
    39001 atttaacatt gacagtagaa ccaggtgttt tattgatgac aataggtcaa tatgttcaag
    39061 atagagattt attttaccca cctgacccag gtgaaaaaag tgctacaatt gcaggtaata
    39121 taaacactaa tgcaggtggt atgagagcag taaaatatgg agttacaagg gattatgtaa
    39181 gaggtcttga agttgtacta ccaaatggag aaattataaa tgtaggtgga aaggtagtta
    39241 aaaatagttc tggatatagt ataaaggatt tattagtggg ctcagaaggt actttaggaa
    39301 tagttactaa agctatatta aaattgcttc ctttaccaaa gaaaagtata agtttgctta
    39361 taccatttcc agatttatca atggcaatag aaactgttcc taaaataata aaatcaaaat
    39421 caataccaac ggctatagaa tttatggaaa gagatgtaat attggcagca gaagaatttt
    39481 taggtaaaaa gtttccagat aatacatcag atgcttatct tttgcttaca tttgatggaa
    39541 atagcactga agatatagaa aaagaatatg aaaaagtagc taatttatgt ttagaaaatg
    39601 gtgcattaga tgtatttata tcagatacac aagaaagaaa cgattctata tggtcagcca
    39661 gaggtgcatt tttagaagct ataaaggcat ctacgacaca aatggatgaa tgtgatgtcg
    39721 ttgttccaag agataagata gcagagttta taagatacac tcacgagctt caagacaaat
    39781 taaaaataag aataaaaagt tttggtcatg caggagatgg aaatctacac atatatattt
    39841 taaaagatgg tatggatgac aatacatgga aaataagatt aaaagaaact tttgactata
    39901 tgtataaaaa atctagagaa cttagtggtc aagtttctgg tgaacatggc ataggatatg
    39961 ctaaaaaaga gtacttacat gaatcaaatt cagatgctta tatgatgtta attaaaaata
    40021 taaagctagc ttttgaccct aaaaatattt taaatccagg gaaaatatat tagaaatatt
    40081 aatttaataa tatttacaaa acaaaaaata ttaaattaga tttaaatata atattttaaa
    40141 ctttactttt aaatctgaag ctaaattgta aaatttttag gatggcaata tttacttaaa
    40201 tttagaaagt aacataatat ttaagttgat gttgtcatcc taaaagcatg tgtacataaa
    40261 taaagtaaga ctattgtatc ttatataata aagagttaat aaaatgattt ttataaatat
    40321 agttatttta aaaaactact ttacatatat tggatgagta taaaaatcca tagggccttt
    40381 tactaaatct ttattgtttt tataatatat taaattatat atatttgtag cttttatatc
    40441 ataacttatg agtgttttaa aaatcgtatc atctaatgaa aatgatatac ttgaaaactt
    40501 gtttattatt tttatttcag atttattttt tatctctttt agaatttctc tacctttatc
    40561 attaaaagca agtattctta tataaggtat agtatctatg ttttttataa gttgcatgtc
    40621 gcttttttta atacctaaca atatattgtt tagagttcgt ttgattttgg ttaaagtgta
    40681 tcgcttggat ttaattgcta attgtagctc atatagaaat tcagatgtaa agatatcttt
    40741 atagattctg ttttctatgc cttcatttac ttcaaaatac tcttttaaag tgtccatatc
    40801 tctaagtata attgttttta aaatatcaaa gaagaagtca tcaaacatag gtaaaaaacc
    40861 attatctatt ttttcattta ggatgttata agttttttct ggaataacat tttttaaatg
    40921 aaaaaggtct gtattttctt taagtgaagt tcttatagca gtagcagaac aaatatcact
    40981 ctcaatttct tcggaattat attctgattg gaccctggag atagtaaatg gttttatact
    41041 actgtttaaa tggatgaggt tttttatgta ttctataccc agtatgttgt ttgatgaatt
    41101 taatgttttt gataattgtt cctttgaata attttgtata aaattatttt ttttgtcttg
    41161 atgtatataa tcaaaaagtg cattagctct agctgttgga aataacagac catcatctaa
    41221 atattttttt aaaagtaact taaattcatt tggttcattt gctaaaattt cagctagatt
    41281 ataaagaatt tctgtatttc cttcttcact accaaaacat atagaattta tgcagtttag
    41341 tgaatttaaa attgttatag caccatgaga aaaaatttca gcactttgac aagcaaataa
    41401 agttggtaat tctataacta agtctacacc attttcgaca gcaatttttg ctctagtgta
    41461 tttatcaaat aaagctggtt cgcctctttg tagaaaattt ccactcatta ttgctacagt
    41521 atgtgttgca tttgtttttt ctatagattt agataaatga tatatgtgtc cattatgaaa
    41581 tgggttatat tcaactatta atccaagtat gttcataaaa tactcctttt atctttaatt
    41641 attttatata tatcacaatt tattataata tgtataaaat ttaaattttt aattataaaa
    41701 ttaaaaaacg taaaaaaatt tataaaaatg tagaaatgtt acctacataa aaaactggtt
    41761 aaatgttatt aaaataactt tattagctct ttatattata ttattataac aaatgggaaa
    41821 gaataatcta cattaagtta acttgttaat atattattag tgaaatacac aatttaccat
    41881 actagaaata tgatataata taaaaaaaaa gtatatactt ttatattaaa aggtgatata
    41941 ttatttatga aaatcgttta atgtatacaa taatatatct ataacaaaat aataaaagat
    42001 agagttttat ttagacattt attacaaatc aaaatttatt acatattatt tataaaaaaa
    42061 tctaaggagg aaataataat gaaaatatta gtattaaact gtgggagttc ttcattaaaa
    42121 tatcaattaa tagatatgaa taatgaagaa gttttatgta taggattggt tgaaagaata
    42181 ggaatagaag gttctatatt aaaacatgaa aaagcaggta gagatgataa atacgttgtt
    42241 gaacaaccaa tgaaggacca caaagatgca atagcattag ttttagaagc tgttgctcat
    42301 ccagaatttg gtgcagttaa agaaatgaaa gaaatagatg cagtaggaca tagagttgta
    42361 catgctggag aaaaatttgc aacttcagta gtaataactc cagaagtaga agaagcttta
    42421 aaagaatgta tagatttagc tccacttcat aatccagcaa acataatggg aatagatgct
    42481 tgtaaagcta tacttccaga tgtaccaatg gtaggtgtat ttgatactgc tttccatcaa
    42541 acaatgccta aatcttcata cttatatggt ttacctcatg agctatatac taaatatggg
    42601 gtaagaagat atggattcca cggaacttct cataattatg tatctcaaag agcagcagag
    42661 atattaggaa aagatataaa agatttaaaa atagtaactt gtcacttagg aaatggtgct
    42721 tctatagctg ctgttgatgg tggaaaatgt gtagatacat ctatgggatt cactccatta
    42781 gaaggattaa taatgggaac tagatgtgga gatatagacc cagctatatt accattctta
    42841 atgagaaaag aaggtttaga tgctgatgga ttggataaat taatgaataa agaatctgga
    42901 gtatatggaa tgactggaat ttctagtgac ttcagagata tagaagatgc agctaaaaat
    42961 ggagacgaaa gagctcaagc tacattagaa gcgtatgtta aaaaagtaca aaaatatata
    43021 ggcgcttatg ctgctgaaat gaatggattg gatgttgtag tatttactgc aggcgttggt
    43081 gaaaatggaa aggctataag agcagatatt gcttctaaca tggagttttt aggaatgaaa
    43141 ttagataaag aagctaatga tgttagagga aaagaaacag taatatctac tgctgattct
    43201 aaagtaaaaa tgcttttaat accaactaat gaagaattaa tgatagctag agatacatta
    43261 agattggtaa aataattaaa ttaaacctat gcctatcaag taaaaatact tgacaaacaa
    43321 atgctagatt tgtataataa atttggtgat atgttgaggt gaacttaatg aaagttagca
    43381 tagaaaaaat aaatagaaaa gaaactgaca aaatagactt gaatttttgt gaaaaaattg
    43441 atactattag ttattgtgat gagatttaca aattagtatc acctgtaaat ttaaaaggga
    43501 aagtgtcaaa gactaataaa ggtttgtatc tagatataga tgtcaatttt acaattgttg
    43561 acaattgttc aagatgtctt aaagaagtag aaataccact agagtattct atacaaggtt
    43621 ttttagtaaa agaagaagat tatgatgaag atgagtttga ggaatttgat ccttttatat
    43681 tcgatggtga agaaatcgac cttattgata taatagaaca gacattagat tttaatgtac
    43741 ctcataaagt tctttgtagt gaaaactgta aaggtctttg tcaagtatgc ggggcaaact
    43801 taaatgaaga agagtgttct tgcagtgaaa ttacaaacga tgaggaatac atagatcctc
    43861 gttttgctaa attaaaagat ttatttaatt aaattttgac taaggaggtg gcgtaaatgg
    43921 cagtaccaaa gcgtaaaacg tctaaatcaa acacaaaaat gagaagagca gctaactcaa
    43981 agatggaagc aacaggattt gtaagttgcc cacaatgtca tgagccaaaa ttaccacata
    44041 gagtgtgtcc agactgtgga tattataaag gtaaagaagt tgtgtctaag taatagcttc
    44101 taaaaagcat gtagagtata ctctacatgt tttttttgta catataaaaa aataagatga
    44161 tttactagag aaaataagtg gattttatgc atattaaaaa atagaaaaat aataatataa
    44221 gtattgaaaa tttttgtgtg ttactatata ctactattag tagctggtac taattacagc
    44281 tataaaattt ggagggaaca tgaaaaagaa aagtaaagcc caaagacaaa aagagcttat
    44341 agatatgcta aagacagatc ctttttatac tgatgaagaa ttatcaagtc tgtttgatgt
    44401 aagtatacag accataagat tagatagaat gagtctaaac ataccagagc taagagaaag
    44461 agtcaaatca atagcagaaa ctcagagttc aaaagtaaag actttaggag taaaggaaat
    44521 tacaggagaa atcattgatt tatctgtagg gcgattaggt atatctatgt tagaagttac
    44581 acaggacatg atttactcta agactaatac tttaaaagat acgtatattt tttctctagc
    44641 agattcattg gcaatggcta taatagatgc acctaaggtt attatgagag ttgcaaatgt
    44701 aaaaagtttt aagttgatag aacaacaaga taggcttata gcaaaagcag aagtgtatag
    44761 aaatatagat aaaaagcatt atgtaaaagt tgttatcaac aataaagccc aagagcaaat
    44821 atttagagga aagtttatct ttgaagaatt agattaggag ggaaattatg aaaatagtaa
    44881 ttgatggaat gggtggagat aatgcaccta aatctaatgt agaaggcgca gtaaatgcta
    44941 taaaagaata tcaggttgat ttaataatca caggagataa agatttactt gaaaaggaat
    45001 tttcaaatta tgaatttgat agaaataaat tagagatagt tcatactact gagattatag
    45061 aaaacgaaga taaaccagta aaggctataa gaagtaaaaa agattcatct atggtagtag
    45121 cattaaatct tgtaaaagaa ggaaaggcag atgctataat atcagctgga aatacaggag
    45181 ccttacttgc tggtggatta tttgttgttg gtagaataaa aggaatcgat agaccttgct
    45241 tatgttcagc aataccaaat gtaaagcgag gaatgacact tatagcagac tgtggcgcaa
    45301 atgcagattg taaacctaag aatctagttg aatttgcagc tatgagtaat atttattcaa
    45361 gaaaagtttt aggtcttgaa aatcctaagg tagcattagc aaatgttgga ctagaagaag
    45421 gcaaaggcaa tgatttagtc aaaaggtcat atgaagaaat taaaaaatta gatttaaatt
    45481 ttatagggaa tgtagaagct agagaagtta taaatgcata cacagatata atcatatgtg
    45541 atggatttac aggtaatata ttacttaaat ctgctgaagg tgtagcactt tcagttatga
    45601 gtcttataaa ggaaactttt atggccagta caaaaagtaa aataggagca ttacttataa
    45661 aggatgattt aagaaaatta aaaagtttta tagattattc tgagtatggg ggagctccac
    45721 ttttaggtct aaatggagga gttataaaag ctcatggtag ttctgatgct aaagctataa
    45781 aaaatgctat aaatcaagga ataaaatttt caaagggaaa agtcgttgaa gatattaacc
    45841 aatttataag caaatacaat gaagaaaata aaaataacga agatgaataa actcgttttg
    45901 gaggtttaat atataatgaa tacaaaggct ggaatattag gagtaggaag ttatctacct
    45961 gagcaatcat atgataattt tcacttcgaa aaaataatgg atacatcaga tgagtggata
    46021 agtactagaa ctggtattaa ggaaagaaga tttgccaaag agtctgaagc aacttctgac
    46081 ttagcatcta aagctgcctt aaaagctata gaatgtgcaa agttaaacgt agaggatata
    46141 gagctgatta tattagctac aattactcct gatatgtctt tgccttcaac tgcatgtata
    46201 gtacaagatg caataggagc agtgaatgct actgcatttg atatatcagc agcttgttct
    46261 ggatttgtat atggagtaac tattgcaaag caatttgtgg aaacaggttg ctataaaaat
    46321 gtgcttgtaa taggagcaga aacttgttct aagtttttaa attatgatga tagaacaaca
    46381 gcagtattgt ttggagatgg agctggagca gctgttattg gccctgtaaa tgagggtgga
    46441 atactgtcta cacatatggg ctctgatggt aaaggaaaag attgtttaaa agtacctgct
    46501 ggaggttcaa gacttaaggc aagtaaagag actgtagaag ctaatctaca tacaatagaa
    46561 atggcaggta gtgatgtgtt taaatttgca gttagaaaga tggcagaaac ttctttaaga
    46621 gctcttgaaa aagcaaatct aaatacaact gatatagact acttagtgcc acatcaagct
    46681 aatataagaa tcatacaagc ttcttctaag agattagagc ttgatatgaa aaaagtttat
    46741 gtaaatatag acaaatatgg aaatatgtct gctgcatcta taccagtagc attagatgaa
    46801 gcttatagag aaggtaaaat taaaaagggt gataatgtag ttttagttgg ctttggtgga
    46861 ggtctaactt ggggggcttc agttgtcaag tggactttat agtataaaat atctaaaatg
    46921 atttaattaa caaaattaaa cttatacaca aaataaagtt gattaataat aaaaagttta
    46981 cttttatgat ttcaagtgaa ggagaattgt atgaataaaa tttgcaaaat attaaatata
    47041 aaatacccag ttatccaagg gggaatggca tgggtagcta ctgcatcatt agcaagtgct
    47101 gtatctaatg caggaggact tggcataata gcagcaggaa acgcaccaaa agaagctata
    47161 aagaaagaaa ttgttgagtg taaaaaatta acagataaac cttttggagt aaatgtaatg
    47221 cttatgtcgc catttgttga tgatataatt gatttgatta tagaagaaaa agttcaagtt
    47281 attactactg gtgctggaaa tcctgcaaag tatatggata gattaaagga agctggaaca
    47341 aaggttattc ctgtagtacc tacaatagct ttggcacaaa gaatggaaaa gctaggagct
    47401 acagcagtaa tagcagaagg tactgaaggt ggaggacata taggagaact tactactatg
    47461 gtcttagttc cacaagttgc tgatgctgta aacatacctg taatagctgc tggaggaatt
    47521 gtagatggta gaggaattgc agcatcattt gcattaggtg ccagtgcagt tcaagtagga
    47581 actagattta tttgcagtga agagtgttct gtccattcaa actataaaaa cttagtacta
    47641 aaagcaaaag atagagatgc aattgtaaca ggaagaagta ctggtcatcc agtaagaaca
    47701 ttaaaaaata aactatcaaa agaattttta aagatggaac aaaatggagc tactcctgaa
    47761 gaactggata aaaaaggtac aggagcttta agatttgcaa cagtagatgg agacatagaa
    47821 aaaggttcat ttatggcagg tcaaagtgct gctatggtaa aagaaataac accttgtaag
    47881 gaaattatag aggctatggt aaatcaagca agagagatta tgccagcaat agaactgtaa
    47941 atcaggagga gcaagatggg aaaagttgca ctagtattcc ctggtcaagg agctcaatat
    48001 gtaggtatgg ccaaggattt atatgaaaat aatgctgttg ctaaaagtgt aatagatgag
    48061 gctagtgatg ccttaaatat ggatttaaaa aaccttatgt ttaatggaaa tgaagaagaa
    48121 ctttctaaaa ctgaaaacac tcaacctgcc atggttacac atagtgtagc agtattaaaa
    48181 gcggtacaag ctcaaataga tttaaaatat aatgcatgct taggattatc cttaggagag
    48241 tatagtgcgt tggttgcagc agatgcaatt gactttaaag atgctgtatg tttagttaaa
    48301 aaaagaggta agtttatgca ggaaacagtt ccagcaggtg ttggagctat ggcagcagtt
    48361 ttaggtttag atagaaatgt acttgaaaat gtggttaaag atatacaagg aggtattgta
    48421 gaagtagcaa attacaattc tcctggacaa atagttatat ctggtgaaaa tgaaaagata
    48481 gaagaagcaa tggtaaaatg caaagaagca ggagcaaaaa gggcagttaa attaaatgta
    48541 agtggacctt ttcactcatc aatgttaaaa gaagctggtg taaaattggc cagtgaatta
    48601 gaaaaagtta acataactaa acctaaagtt gatgtggtgg caaatgtaaa tgcagattac
    48661 tataaaaacg aaggtaaaga cctgcttata aaacaagtaa gttcatctgt tctttgggaa
    48721 gattctatag aaagactttt aaatgatgga tatgatactt ttatagaaat gggacctgga
    48781 aaaactttaa aagcatttat taagaagata gcttccaata aaaaatcaaa tgtcaatatt
    48841 tataatatag atggtataga ttctcttaat gaatttgtac aaaattatag aaatggagag
    48901 atataatgat aaatcttaca ggacaagtag cagttgttac tggtggctct aggggtatag
    48961 gaaaagaaat agcaaaaaaa ctagcatctt ttggagctga tgtagtaatc aattatactt
    49021 ctaaagaaga tgaagcacta aaaactaaaa atgaaataga aagtatgggg gtaaagtgta
    49081 cctctataaa atgtgatgta tctaaatttg atgaagtgaa tcaaatgata gattctgttg
    49141 taagcgaatt tggaaaaatt gatatattgg ttaataatgc aggcataact aaagatggtc
    49201 tgcttatgag aatgaaagaa gaagattttg atagagttat agatataaac ttaaaaggtg
    49261 tctttaattg tacaaaagca gttactaaac ctatgatgaa aaagaagtat ggaagaataa
    49321 taaatatgac ttcagtagtt ggaattatgg gtaatgcagg gcaaactaat tattgtgcat
    49381 caaaagcagg tgtaattgga tttacaaaag cttctgcaag agagttagca tcaagaaaca
    49441 taaatataaa tgcagtagca cctggattta tagaaacaga tatgactaaa gtactaagtg
    49501 atgatgtaaa agaatcaaca ctagcaaaca taccaaagaa atcttatggt aaaccagaag
    49561 atgtagccaa tgccgtagca tttttagtta gtgacatgtc aagttatata acaggacaag
    49621 taataaatgt agatggtgga atggtaatgc aataataatt taaaaagtag agaaatctat
    49681 taaaataaaa aattttagga ggtacacaat gtttaataaa gttgtagaaa taataataga
    49741 gcaattagga gtagaagata aagaaataac tatggaaaca tcattaatga aggatttaga
    49801 agcagattca ttagatgcag tagaaataat aatggcactt gaagatgaat ttggtataga
    49861 aataccagat acagaagcag aaaacttcaa atctatagga gatatagtta agtatataga
    49921 agctaataaa tagtcgagct ttaaaaaagt ggaggtatcc gatgaataaa agagtagtaa
    49981 taacaggact tggatgtgtt acgccgttgg gaacaggaaa agaagagttc tggagtaata
    50041 taaaatctgg agtatctggt atagataaaa taactaattt tgatgctagc acatatcaaa
    50101 ctcagatagc aggagaagtt aagaattttc atccagaaga atatataagt aaaaaagaat
    50161 tgaagagatt agataaattt gctcaatttg caatagtatc tgctaaatta gcagttgaag
    50221 atgcaaatct tgatttagat aaagttgata gagaacgttt tggtgttata ataggttctg
    50281 gaataggtgg agttgaagct atagaaactc aacataaaat tcttttggaa aaaggaaata
    50341 aaagagtaag ttcacttttt gtacctatga tgataggaaa tatggcagct ggtcaagttt
    50401 caatattttt aggagcaaaa gggcctaaca ctaatgtatg tacagcttgt gcatcaggaa
    50461 ctcattcaat aggtgatgct tttaaggtaa ttcaaagagg tgatgcagac attatggtag
    50521 cagggggttc tgaagctgct gtaacaggtc ttgcttttgc tggattctgt aacatgaagg
    50581 ctatgtcaac tagaaatgat gaccctaaaa ctgcatcaag accatttgat aaagacagag
    50641 atggttttgt aatgggagaa ggagcaggta ttgttatctt agaagactta gaacatgctt
    50701 tagcaagagg cgctaaaata tatgcagaag tagttggata tggtttaact gctgatgcat
    50761 accatatgac aactccagct gaaaatggag agggagcagc taggtctatg aatatggctt
    50821 tgaaagatgg aaatgttcca ttagaagaag tagattatat aaatgctcat ggaacttcaa
    50881 cttattacaa tgatttatat gaaactatgg ctataaaaac tgtatttgga gaaaaggcat
    50941 atgacttatg tgtgtcatca acaaaatcta tgactggtca cttattagga gcatcaggtg
    51001 ctatagaggc tgttgtttgt gctatgagta tagaagatag ttttgtgcct ccaactataa
    51061 acatacaaga agttggtgaa gatttggatt tagattatgt tccaaatcaa ggtaaagaaa
    51121 aaaatattag atatgcacta tcaaattctt taggatttgg tggtcataat gctacaatag
    51181 tactaaaaaa atatgtataa ataaatatta aatataaaac taaaaaacaa gcacttgttt
    51241 taactgtata aatttatatt agcttaaatt taaagtctcc taaattattt taggagactt
    51301 ttttattaag atttaagtct aggatatgtt gtaaatcatt ttgatatatt gtattattaa
    51361 ttattaagag gttatttata tatgcaagtt ttcattctac aatatacaaa aggaggacta
    51421 aaattttgaa ttttagacta ccaaagaaaa ggttacccaa aaagataatt tttatatgta
    51481 taatacttat tagtattatt ttgtttataa agtatgacca aaatggattg aaagaaagag
    51541 aaattataaa taagggaaaa tatatgtctg aaagccttgt ggcagataag gagtatgatg
    51601 aagcaaaaaa agtggttaag acttctttcg aatctattcc agaaaaaaaa tacaataaag
    51661 tatataatga agtttgggat atgttaaaga ctatttcata tgttccagat ggaacgaaga
    51721 tagtcattga ttctttagaa aagatgagag aatcagatgt gaaattatct gatgaatgta
    51781 gatttaatat agaaaaaaga ttagcatcag tgtatataat ggataataat tattctaagg
    51841 cagtagattt aactgtaaag tctataaagt tggctgagaa attggggaat aattatgaaa
    51901 aagcaagact agatgttgat ttggcgagca tatttttaaa gataggtggc tatgaaacag
    51961 gagagaaatt aataaaggat tcttttaaaa tagatattga tgaaggtgaa aaaaatggaa
    52021 tggttagatt atatgctatt ataaatctag cagaaatata tgtagaagag ggagaatatg
    52081 ataaagctat tgaaataagt agcaggataa aagattataa aaagtttgta aatacggata
    52141 attacaatga ttttgatata atggcctcta taatgcagtc aaatgcgtat gtgggcaaaa
    52201 ataatataca aaaggcaaag acttttttag aaaaagctga ttatcttata aaatcagata
    52261 gaacagttta tatattagat aaagatatgt actattatat ggcaatggga aacttagaat
    52321 ataaaagcga aaattataat tctgcaatag ataattataa aaaaagttta gagatatcta
    52381 ccaaaagaaa gttaacccag gagaaaataa aaaatttaaa taagatatta aatatatatg
    52441 aaaaacaagg aaatatagaa tctttaaatg agtatcaaaa gatgttaata aatgaatata
    52501 aagagaacaa aagtataaga gattcagaga ctagtttcta tataattgat aaagtatcaa
    52561 acgaaagtaa gctatttgaa aaaactaaaa aagaaataaa atattataaa atattattta
    52621 cagtaatttt aattgctata ttagggtcta cttttttata caaccgattg aagtatttta
    52681 aagcacaaaa tttacatgat ggtcttacaa atgtttataa tagaaaaagt tttgatatta
    52741 tgtatgaaaa gtacagagag aaagatgata attttgcact tgtgatgata gatattgata
    52801 atttcaagct cataaatgat aattatggac ataaatttgg tgacactgtt ataaagggaa
    52861 taacaaatac catttgtgtt atgttagaac aagatgataa agtctttagg tacggaggag
    52921 aagaattttc tgtattaata agaaataaat ctggtgatga agtagcagat ataattgaca
    52981 gtataagggt tgcaattgca aataaaaagt ggaatgatga tgtgactgtg actataagtg
    53041 caggtgtagc tcatgtttca gatagcaaag atgtactaga agaagctgat aaaaatttat
    53101 ataaagcaaa acaacttggt agaaataaag tagtatataa gtaattatat actatataaa
    53161 taagaggtat aaatatgaaa caatcaatag ctatagtaac tgataaaata actaaactat
    53221 catctttctt agaagaaaat atacgtttgg ttttaggtaa ttatattgat ataaaccact
    53281 attatctgga agttttaaaa gagaatgata aaatacaagg tgattttgta ctagtaatga
    53341 atgatgatag attaaacagt atgagaaagc atttagtaca agatagtaag attatagtga
    53401 taaggagaac acttaaagaa aatgaaatat atggattatt ttcaatacca aatggaactg
    53461 aagtattggt tgtaaatgat acaaaagaaa ctaccttaga aacgataagc ttattttaca
    53521 aaataggagt aaaaaattta aagtttactc catatattga aggaaaaatt tataaaaata
    53581 tagacatagc tataacacct ggagtaaagg gaaaagtacc aagttatata aataaagtaa
    53641 tcgaccttgg aaatagatat attgatatat ctacctttat agaaataata aatggtctta
    53701 gaatagatgt taaagaaata cgtaaaaatt taatggcata ttctgagagt ttaataagtt
    53761 tagataatgg agttaaagat aattataggc aactgttttt aaaaatagaa gaacaagatg
    53821 ttatattgaa tctatcaaaa gatggaataa tatttacttc agcagatggt ataataaaca
    53881 catttaataa agaagcttta aaaattttag gtataaatga aaatccacaa ggcaaaaaca
    53941 tagaagatat catttctgaa gatttaaata ttttacttga agacaaagaa ataattgatg
    54001 aagtggtatt tacaaataaa aaatatataa atgtaaataa aaaaagtatt ttttctatgg
    54061 ggaataaagc tgggatatat tataacttac aagaaataac gtatataaaa aaattagaac
    54121 aaaatcttac taataaatta agagaacaag gtcagatagc aagatataca tttaaagata
    54181 taaaaactaa aaataaaaat atggtaaagt gtgtagaatt ggctaaaaaa atatctaaat
    54241 cagacctttc tgtattaata ataggagaaa gtggtactgg taaagaatta ttatcacaat
    54301 caattcataa tgcttccaat agaagtaatc aaccgtttat agcagttaat tgtgcagcag
    54361 ttccagatag tctattagaa agtcaactgt ttggatatga aaaaggctct tttacaggag
    54421 ctttaagaga aggaaaaaag ggtctatttg aacttgctaa taatggaact atatttctgg
    54481 atgaaattgg agatatgcct ccattgctac agacaaagtt actaagggta ttacaagaaa
    54541 agcaggttat gcctataggt tcccataatg ttataaacat agatgttagg gtcatagcag
    54601 caacaaacaa aaacttacta aagatgatta gagaaggaaa atttagagag gacctgtatt
    54661 atagactaaa tgtattgcca atagatgtac catcattgag gaatagaaaa gaagatataa
    54721 taacacttat gaatttcttt ttgaaaaaca atataagact ttcgccagaa gttataacta
    54781 ttttagaaaa atataattgg ccaggaaata taagagagtt acaaaatgtt gcttcttatg
    54841 taagtctaat gtgtgatagt atggttttta gagatgactt accaccatat ataagggtag
    54901 aatgtgctaa caattatgaa gatggatttg gttatacaag aaaagaattt gaggaaatac
    54961 tgaggattct atatgaaaga agagagtcat cctctggaat tggaagaggg tttataatcg
    55021 aaaagcttat acaggaaggt attgagattt ctgaaagcaa agttagaaag gtgctatctt
    55081 atttaagtga atgtggatac atatcatcta aatctggtag aggaggaagt caaataacct
    55141 cagaggggat aaaactttat aataatataa attaagctaa gtatttgata ttgaaatcac
    55201 atattttgaa tttagatatt taaataataa taaactttta ta
//
LOCUS       DAEPUT010000018        55036 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.018, whole genome shotgun sequence.
ACCESSION   DAEPUT010000018 DAEPUT010000000
VERSION     DAEPUT010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55036
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.018"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..950)
                     /locus_tag="KRL22_001212"
     CDS             complement(<1..950)
                     /locus_tag="KRL22_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1271714.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKN"
     gene            1449..2810
                     /locus_tag="KRL22_001213"
     CDS             1449..2810
                     /locus_tag="KRL22_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1271715.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            2901..3605
                     /locus_tag="KRL22_001214"
     CDS             2901..3605
                     /locus_tag="KRL22_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1271716.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            3804..4115
                     /locus_tag="KRL22_001215"
     CDS             3804..4115
                     /locus_tag="KRL22_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1271717.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            4137..5450
                     /locus_tag="KRL22_001216"
     CDS             4137..5450
                     /locus_tag="KRL22_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1271718.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            5527..6837
                     /locus_tag="KRL22_001217"
     CDS             5527..6837
                     /locus_tag="KRL22_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH1271719.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            6863..7594
                     /gene="chbG"
                     /locus_tag="KRL22_001218"
     CDS             6863..7594
                     /gene="chbG"
                     /locus_tag="KRL22_001218"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBH1271720.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            7607..7924
                     /locus_tag="KRL22_001219"
     CDS             7607..7924
                     /locus_tag="KRL22_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1271721.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(8036..8500)
                     /locus_tag="KRL22_001220"
     CDS             complement(8036..8500)
                     /locus_tag="KRL22_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271722.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILDGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            8770..9708
                     /locus_tag="KRL22_001221"
     CDS             8770..9708
                     /locus_tag="KRL22_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1271723.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            9836..10849
                     /locus_tag="KRL22_001222"
     CDS             9836..10849
                     /locus_tag="KRL22_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH1271724.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            10855..11877
                     /locus_tag="KRL22_001223"
     CDS             10855..11877
                     /locus_tag="KRL22_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH1271725.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMNVIK
                     TFLWQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIVVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            11892..12674
                     /locus_tag="KRL22_001224"
     CDS             11892..12674
                     /locus_tag="KRL22_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271726.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            12686..14026
                     /locus_tag="KRL22_001225"
     CDS             12686..14026
                     /locus_tag="KRL22_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1271727.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(14121..16400)
                     /locus_tag="KRL22_001226"
     CDS             complement(14121..16400)
                     /locus_tag="KRL22_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1271728.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQGISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(16737..17900)
                     /locus_tag="KRL22_001227"
     CDS             complement(16737..17900)
                     /locus_tag="KRL22_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1271729.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKTGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            complement(17913..18188)
                     /locus_tag="KRL22_001228"
     CDS             complement(17913..18188)
                     /locus_tag="KRL22_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1271730.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            complement(18209..19183)
                     /locus_tag="KRL22_001229"
     CDS             complement(18209..19183)
                     /locus_tag="KRL22_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH1271731.1"
                     /translation="MHILKSVKKIPGGLMVCPLLFGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVK"
     gene            complement(19454..21367)
                     /locus_tag="KRL22_001230"
     CDS             complement(19454..21367)
                     /locus_tag="KRL22_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1271732.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASKK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            complement(21544..22758)
                     /locus_tag="KRL22_001231"
     CDS             complement(21544..22758)
                     /locus_tag="KRL22_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBH1271733.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            23002..24384
                     /locus_tag="KRL22_001232"
     CDS             23002..24384
                     /locus_tag="KRL22_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH1271734.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            24396..25745
                     /locus_tag="KRL22_001233"
     CDS             24396..25745
                     /locus_tag="KRL22_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH1271735.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEVIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            25895..26428
                     /locus_tag="KRL22_001234"
     CDS             25895..26428
                     /locus_tag="KRL22_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1271736.1"
                     /translation="MSGAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINHYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            26512..27321
                     /locus_tag="KRL22_001235"
     CDS             26512..27321
                     /locus_tag="KRL22_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1271737.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            27731..29776
                     /locus_tag="KRL22_001236"
     CDS             27731..29776
                     /locus_tag="KRL22_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1271738.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKKNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            30037..31236
                     /locus_tag="KRL22_001237"
     CDS             30037..31236
                     /locus_tag="KRL22_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH1271739.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            31288..31983
                     /locus_tag="KRL22_001238"
     CDS             31288..31983
                     /locus_tag="KRL22_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBH1271740.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            32000..32677
                     /locus_tag="KRL22_001239"
     CDS             32000..32677
                     /locus_tag="KRL22_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271741.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            32788..34389
                     /locus_tag="KRL22_001240"
     CDS             32788..34389
                     /locus_tag="KRL22_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1271742.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNIN
                     KEIDCCGKVMTPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRTPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     YDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            34838..36127
                     /locus_tag="KRL22_001241"
     CDS             34838..36127
                     /locus_tag="KRL22_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH1271743.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            36156..36836
                     /locus_tag="KRL22_001242"
     CDS             36156..36836
                     /locus_tag="KRL22_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBH1271744.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PKNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            36937..37476
                     /locus_tag="KRL22_001243"
     CDS             36937..37476
                     /locus_tag="KRL22_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBH1271745.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            37652..38671
                     /locus_tag="KRL22_001244"
     CDS             37652..38671
                     /locus_tag="KRL22_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH1271746.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            38959..40149
                     /gene="dltD"
                     /locus_tag="KRL22_001245"
     CDS             38959..40149
                     /gene="dltD"
                     /locus_tag="KRL22_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBH1271747.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            40270..41784
                     /locus_tag="KRL22_001246"
     CDS             40270..41784
                     /locus_tag="KRL22_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HBH1271748.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDERNFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            41784..42932
                     /gene="dltB"
                     /locus_tag="KRL22_001247"
     CDS             41784..42932
                     /gene="dltB"
                     /locus_tag="KRL22_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBH1271749.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            42951..43181
                     /gene="dltC"
                     /locus_tag="KRL22_001248"
     CDS             42951..43181
                     /gene="dltC"
                     /locus_tag="KRL22_001248"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBH1271750.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            43398..44183
                     /locus_tag="KRL22_001249"
     CDS             43398..44183
                     /locus_tag="KRL22_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH1271751.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQVVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            44462..46372
                     /gene="phnW"
                     /locus_tag="KRL22_001250"
     CDS             44462..46372
                     /gene="phnW"
                     /locus_tag="KRL22_001250"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBH1271752.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNLWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     DYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEYFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            46731..47552
                     /locus_tag="KRL22_001251"
     CDS             46731..47552
                     /locus_tag="KRL22_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271753.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     VNIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVSEIKNISEKIKLKKDK"
     gene            47593..48360
                     /locus_tag="KRL22_001252"
     CDS             47593..48360
                     /locus_tag="KRL22_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HBH1271754.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGAIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVVNIEYSDNLSVSDNSTVKNSIKVG"
     gene            48368..48988
                     /locus_tag="KRL22_001253"
     CDS             48368..48988
                     /locus_tag="KRL22_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HBH1271755.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEVDLTKEINDISIKLS"
     gene            complement(49288..49875)
                     /locus_tag="KRL22_001254"
     CDS             complement(49288..49875)
                     /locus_tag="KRL22_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH1271756.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(49961..50398)
                     /locus_tag="KRL22_001255"
     CDS             complement(49961..50398)
                     /locus_tag="KRL22_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1271757.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            50502..51500
                     /locus_tag="KRL22_001256"
     CDS             50502..51500
                     /locus_tag="KRL22_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HBH1271758.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            complement(51620..52546)
                     /locus_tag="KRL22_001257"
     CDS             complement(51620..52546)
                     /locus_tag="KRL22_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH1271759.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            52932..54536
                     /locus_tag="KRL22_001258"
     CDS             52932..54536
                     /locus_tag="KRL22_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1271760.1"
                     /translation="MKAKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENHIRPVMIHAQTVREDQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
BASE COUNT        20680 a         6324 c         9371 g        18661 t
ORIGIN      
        1 aaatttttta gaataattat gtattcatca cctccaatac gataaactat atatttttta
       61 tttattacat attgtataat tttacttgct tgcttaatat ataagtctcc tgtctgatgg
      121 ccaaatttat cattaatctt ttttaaacca tctaaatcta ttgatatgat agatattaga
      181 ttctttagat ttgaattgtt taagttattc atatctattt caaaagcatt tctatttttt
      241 aggcctgtta aataatctgt attagcaaaa tcagtatatg taggattaga tattctttta
      301 aatagaatca ctgcaatcaa tgctgatatt agacaagtta ataatgctat tattggtgta
      361 actatactta taaatttaaa tgtattgtat tgatgttttg cttcaaattc aattcctatt
      421 actccaacaa ccttaccaac atcattgtga ataggaaaat acgatataaa tatgtatccc
      481 caagatgttg atttaatctt tttaggtaac aatatatgat tatctaatgc tttgttaagg
      541 tctccccaaa tctctttttc tatcaaatca ccagcatttc taaaatcact cctagatgaa
      601 tttaaaccat caacaacata tactagtgat ccatcttttg tttttttagc agtatataga
      661 tacatgactc cagtagtatt ttttacagat tctaaaagga ttttagaact tttataagac
      721 ttttttgatt ggtcttcttt agaattaatt tcagtaaagg tatttttatc aatatttctt
      781 tctacatatt catagatatg ttttgacctc tcacttaaag agtatatcat gctcttataa
      841 gttagtgtat aattaaaaaa atatacacat gaggaagata ttattacaat aattgcagta
      901 agtattgaaa cctgcatatc aactctattg aattttttat ttattttcat agcttaaatg
      961 tcttgtgaaa agaacctccc acaatctccc cataattaat atatatctat aaatttcacc
     1021 ataatatatt catatattat caaatttgtg tggaaattac aattagtaaa catgcttaaa
     1081 gcattcaaat atagtttttt tattattata gtatactatt ttatgtataa ataaaattat
     1141 atataaatca ttgatattgg ttgtttatta atggaagata ccgtataaaa tattctaatt
     1201 ggttacgata tgtatactta attgaagtta agttaagggt tagaatatgt attgatgaaa
     1261 tggctagatt tatattcata agtattaatt ttatcataga taggtaaaat actgtatctt
     1321 aaacataagt atgattgaga tgcaatcctg agatatgata atataaattg aaggatagtg
     1381 aactcaatca aataaaatga ttaatctagc tatataagca aataaattta atataaaaga
     1441 ggtggaaaat gaaagacaga cttaatttaa cagaaggaag aattacagaa aaattactta
     1501 agctatcact tccaataatg gggacttcat ttatacagat ggggtataac atgatagata
     1561 tgatatgggt tggtaaagcc ggaagtaaag cagtagctgc agttggaaca gctggttttt
     1621 ttccatggct tgcaatggca tttattatga tttcaaaagt aggtggagag ataaaagtag
     1681 cacaaagtat tggtgcaaat aatataagca ctactaaatc atatatgaag tcagcaatag
     1741 aaataaatat tatactagca ataatatata caatttcttt aatagtactt aataaacaat
     1801 tgataggttt ttttagatta ggagacttag aagttataac catgtctaga cagtatttga
     1861 taatagtagc tctaggtatg gtattttatt ttattaatcc agtatttact gcaattttca
     1921 atggtcttgg aaatagtaaa actccttttc gtattaatac agtaggatta ataactaata
     1981 ttatacttga ccctatatta atttttggat ggggatttgc tccaaaactt ggtgttgcag
     2041 gagctgctat tgcaactgta tttgctcaga tagtagttac tacatgtttt atatatataa
     2101 tagttaaaag taaagaagaa tattttaaat taagactatt taaagaaata gagactaaat
     2161 attataaagt tctgtataaa ttgggattac ctatagcaat acaaagtggt atgtttacag
     2221 tattctcaat gctattagga gtaatagtag catcatgggg gcctgtggct gttgcagtac
     2281 aaaaagtagg ctcacaaata gaagcaattt cctggatgac ggctgaaggg ctatcagttg
     2341 cattaggcag ttttgttgga caaaattatg gtgccaagaa gtattctaga ataaataaag
     2401 gttgcaaaat agctataact gtatcttctg tacttggtat aataactact ttagtattag
     2461 tgtttgcagg agagagtata ttttctattt ttatagatga aagtgaggca atagaaaaag
     2521 gagcagttta tcttaaaata ttaggctatt ctcaattttt tatgtgttta gaaataataa
     2581 caacaggagc tttcaaagga ttagggagaa cctatatacc ttctattata attactatac
     2641 tgactggtgc aagagtacca ttggcttact ttatatctag accagaaatg ttgggtctaa
     2701 atggtgtatg gtggagtata accttatcaa gtatattaaa aggtatatta atgataagtc
     2761 tatttatatc tttattaaaa ctcggaaagt tgtacaagat ttctgaataa aatttaaatt
     2821 atcttaaatg tatagacatt ttctttgttt gtatataaaa ttatcttatt atataaaaga
     2881 tttaataagg agtgaattaa atgaaagagc caatttataa agttatagaa aatcatgtta
     2941 gagagttaat aaattcagac agtttgaaag aaggggattt aatcccttct gaaaaacagc
     3001 tgagtgaaga atttaatgta actagaatga ctgtaaggtc tgcacttaat aatctagtta
     3061 aagaaggcta tataactaga caaagaggtg taggtagtat agttattgca aataatatat
     3121 atgataatat atcgtctgta agtggattta ctaaagagat ggaaagtaaa ggctataaag
     3181 tatctaatat attggtatct cttgaaatag ttcaggcaga tgaaaattta tcaagtaagt
     3241 tgaatataag tttagaagaa aatgtttggg aaataaaaag agtaagatta gctaatgatg
     3301 caagagtttc atatatgatt acttatatgc cagttaagtt atttccaaat ttaaataaga
     3361 ctcattgtga aaattctctt tataattttg ttgaagaagt gtgtggatac aagatagcca
     3421 tgtcagagag agaagtacaa gctgtaatat cgaatgaaga atgtatggat aatctaaaat
     3481 tagaagaacc agagccactt ttatatataa gccaaatttg taagttacaa aatagtgaga
     3541 tttttgagta ctcacacaca tatcactatg gatatacatt aactttgaat gctgttgtcg
     3601 aataaaattt aaataaaatg aaaaagtttt cttgaaatgt atatacattt ggtatataat
     3661 aatatcaaga attaaatgta tatacattta aaaataagat atatacatta agaaaaaatt
     3721 aatagaaaag catattttaa atgtatagtt taaaaattta tgacttaaaa aatatttaat
     3781 gaatctaatt tggaggggaa aaaatgataa aaataatgtt agcttgttca gcaggaatgt
     3841 caactagttt attagttaca aaaatggagg atgcagcaaa ggaaaacggt atagaagcaa
     3901 aaatatgggc tatatcagaa gtgaacttaa aaaatgaaat agaaaattgt gatgtcttac
     3961 ttttagggcc tcaagttaga tatgtattag gaaaagcaac tgaaatggca aaaccatata
     4021 atattccagt agaagttata aatatgatgg attatggaag atgtaatgga aaagctgtgt
     4081 tagatagagc tgtagagtta aatagttcaa aataaagttg tactggagga tgtaaaatgg
     4141 aaaaattcat gtcatttatg gataaatata tagtgcctgt agctgctaaa ataggagctc
     4201 aaaggcactt agtagcagta agagatgcat ttatagtaat gatacctata actatggtag
     4261 gtgcattggg aacattgata aataacttac cattggaagc atacaaaaat ttgatggcaa
     4321 gtatatttgg agaaaactgg accacatttg gaggcgacct ttggtgggga gcaataggta
     4381 caatggcagt attcttagta ataggtgttg cttattttct agcaaaatct tatgagagtg
     4441 atgggttaca atctgggctt atagctttat ctatcttttt tataatggct ccacaaattg
     4501 gtaaaatagt tcctgaggga ggaactacag tagttgaagg atggggaatg atacaacaaa
     4561 cctacttagg tacagcagct ttattctctt ctatattaat aggattatta tcaactgaga
     4621 tatttgtaag attatctaag gtaaagaaat taactataaa aatgccagat ggagttccac
     4681 cagcagtttc aagatcattt gcaaagttaa taccaggaat gttaactata atgatattta
     4741 ctgtaatagg aatatttata aaaatgcttt ccaatggaag tttcttaaca gatattttaa
     4801 atacttattt aggagcacca ctatcaaatg tagctgatag tttaggttct acaatgctta
     4861 ttgcatttat aattcatata ctttggactg ttggacttca tggtgcaaat atagcacttc
     4921 cttttacaga aactatactt atgaaattag gtggagaaaa tgctgccttg gctcaagcag
     4981 gagcaacgga aggataccat gtacttgcag gtgcattctt tgatgcattt gtatatttag
     5041 gtggttctgg aatggtattg ggattaatag tagctttatt aatagctgga agaagacgta
     5101 aagagatgat agtattaggt ggtccacctg caatatttaa cataggagaa ccattgatat
     5161 ttggacttcc aatagtttta aatcctatat ttatgattcc atttgtactt gcaccagtaa
     5221 tatgtagtgc tgtatcatac ttagcaatag attttggatt agtagcacca gtaattttac
     5281 ctaaaatacc ttgggtaaca cctcctatat taggtggagc aatggctaca ggtgactgga
     5341 ctggcggagc tttagcacta tttaatttaa tattatcaat attaatatat attccatttg
     5401 tcatagcgtc tgaaaaaatg gaagctaata aattgaaaat taacaactag gtagttttat
     5461 ttcggtaaat aaatgtatag agttttgtag agtatattaa attataggta aggatggtat
     5521 aatgagatga aaaagggact aaaaatagtt acaattggag gaggttcaag ttatactcct
     5581 gagcttgtag agggttttat aaatagatat gaagagttac ctgtaaagga attatggctt
     5641 gtagatatag aagctggaaa agaaaaatta gagatagttg gaaatctagc taagaggatg
     5701 gtaaaaaaag ctggagtaga tatgaaaata aatcttactt tagatagaag agaagctcta
     5761 agagatgcag actttgtgac aacacaactt agagtaggtc ttttagatgc gagaataaaa
     5821 gatgaaacta ttcctttatc tcatggagtt atggggcagg aaactaatgg tgctggaggt
     5881 ttatttaaag cccttcgcac aataccagtt atatttgata taataaaaga tgtggaagaa
     5941 ttatgtccaa atgcatggat ggtgaatttt acaaatccaa caggaataat aacagaggct
     6001 gtattcaaat atactaattt tagaagatat ataggtctat gcaacgtgcc aattcattta
     6061 aaaaatgatg ttgccaaact atttaatgta gaaagtgaca gaataagtat ggattttgca
     6121 ggtcttaatc atatggttta tggtctaaat gtatctttag atggagaaga tgttacaaaa
     6181 gaagcaattg ataagtttgt caaagcagat ataagtatgc aaaatataaa ggcaattgat
     6241 tttaatgctg aatttgtaaa atctttgggt gcaatacctt gtccatacca tagatactac
     6301 tataaaacta aagaaatgct tgaggatgag ttgagagagt ttaaagaggg aaaagctaga
     6361 ggtcaagtag ttaaagaatt ggaagaacaa ttatttgaat tatataagga tgaaaaatta
     6421 gatgtaaaac cacctcagct tgaaaaaaga ggaggggctt actatagtga tgctgcttgt
     6481 aatttaataa gttctatata caatgacaaa aaagatatcc aagtagttaa tacattaaat
     6541 aagggttcta taagagattt taaagatgaa caagcagtag aagtaagtag tgtaataaca
     6601 aaaaatggtc caaaaccaat aagtatagga tatttaccag attctgtgca tggattagta
     6661 agtcaaatca aatcatttga agtattggca gctaaagcag ctgtatatgg cgattatgaa
     6721 tctgctcttt tggcactttg tataaaccca ttgattccat ctgatgactt agcaaaaact
     6781 atattagacg aaatgttgga agctcataaa gattatcttc ctagatttaa tagatagttg
     6841 tctatagaaa gtaggttatg gtatgactaa aattataata aatgcagatg attttggata
     6901 ttgtgaagct gtgaactatg gaataatttc agctcataat aatggtatag ttaggtctac
     6961 ttctatgatg gcaaatatgc ctggggtaga acatggagta ggcttactta aagaaaataa
     7021 aactttaaat tgtggagttc atatgacttt aagttgtggt agaccattat tatctaactt
     7081 aaaaactatt gttgataaag acggtttttt tattaggagg attacagacg aaattattga
     7141 aaaaatggat tgtgatgaga tttatagaga actttgtgct caaatagata gggtaaaagg
     7201 gcttggaata gatatatctc atttagatag tcaccatcat atccatactt tagtaagttt
     7261 aaagccagta atagagaaga ttgtaaccaa gtataatctt ccaataagag gtggatttga
     7321 atataattta gagtattcta aagtagttcc tttaatagat agtttttata aggaaaatgt
     7381 aagtgaagaa tattttataa aaaatataga cgaaataatg aagtatgatg tagtggatat
     7441 tatgtctcac ccagcttttt tagatgatta tattttaaat tctacatctt atgctattga
     7501 tagaacgaaa gagcacaaga tacttacatc taaaaaagtc aaagaatttt tagaaaagaa
     7561 tggattagtc atatcaagct atagagatat ttaggaggtc gaataaatgg atgagaagat
     7621 gatagagata tcttttggaa taattggatt tgcaggtgat gcgaaagggc tagcatttga
     7681 agcaataaaa gaagcaaaga gcgggaatat agataaagct agagaatgta ttgaaaagtc
     7741 gaaagaatca attcataaag ctcataaatt ccaaacagaa ttgatacaaa atgaagctaa
     7801 tggtaataaa actgaaataa gtgttatact tattcatgca caagaccatt taatgacagc
     7861 tatgaatttt caacaattag cagaagaatt tatagatgta tatgaaagat tagaaagtaa
     7921 gtaatttaaa attattatta aaaaagagtg tataaaaata atttttataa ttattaaatg
     7981 cactcttttt ttatttaagt agagtttagc aatatagtat tatgttattg atactttaaa
     8041 atttagactt ctcataattg taaggtatac tagtaccaac aactacatct tcaatttttt
     8101 caacaataag ccaatcatcc atatttcctt gatggtcaaa atcaagaggt gttatttctt
     8161 caacattttc aaattcaact aagcataaac attttttatg ccaacgaact ttttgctttt
     8221 cagataaatt taattttggt tgattttcat ttaaaatttt agaaatttca tcttctgtta
     8281 atttaacata gttttctacc tttttaacag tggcttttgc agatattttt gcagttcctt
     8341 tttccataaa ataaagtaac tcatcttcaa atactctact atgtggtatt tttctaccag
     8401 cagcacctct aataaccatt gtttttgttc catccaagat tttatctaag accttttctc
     8461 ctttttttcc tgcattatca caatatacta aatgtaccat gttttgaatc ctccctacta
     8521 aattccttat ctataaattg cattttatca ttgtttaact gaaaagtcat tgtatttgtg
     8581 tccaattctt aaaaaaaata ctgtttaata taagaaaacc ttatctaagc tatatataat
     8641 taagattaat taggaatttt tatcctttta caaaataata ttgactaaaa atagaaaaat
     8701 gctataataa atatgtgctt atgataatca atatcatgta agtataataa acaagtagga
     8761 gaagtaatca tgaaaaaaat aaaatcactt gcaatattta tatctattat aactacgtta
     8821 gtacttgtta cagcatgttc agataagaat acagaggata aagataaatc agagacaaga
     8881 gttgtacaat ctgttaaagg agaggttaag ataccatcaa atcctaaaaa aatagttgat
     8941 atatcaggaa gtagtgaaga actattatta gcaggttata agcctgttgc aacagcaaat
     9001 gtagactcat atgaaactga taaattacca agttacataa gagaagagct taaaggtgta
     9061 aagatagttg ggcactcaat gatggatact atggatatgg aagctatatt agaagtaaat
     9121 cctgatttaa taataatgag tcaaagacaa gaaaaaatat atgaccaatt aaaagaaata
     9181 gctcctgtag ttatgatgaa agattatgca aatgactgga gaagcaagtt aactgatgtt
     9241 tcaaagttat ttgacaaaga agaagaagct aaaagttggc tacagaagta tgatgaaaaa
     9301 gctacaaagt taggtaagga agttatagaa aagaatggag aaaaaactta tttaccagtg
     9361 ttggcaagtt caggtcaatt tatggtattt agtgatggtg gaataggtac tctaatcaat
     9421 gatgatatga aattagctag acctaagaat atgccaaaac aggatggaat aacactacca
     9481 atggtaagta tggaaggttt aacagatata gatgcagacc atatagttgt aattgctaca
     9541 gaagcagata aaaaagattt agaaaatagt gctatctggg ctcaaataag agcagtaaaa
     9601 gatggtaatg taacaatact tgatgctgct ccatttttca gtcaatcata caatccaatt
     9661 ggaaaagagt tattattaga atcagttaaa aatgaattaa caaagtaatt cttaacttag
     9721 taggtgtgag ataatgatat tcatttttca cacctatttt taataaatct taaaattaaa
     9781 atacttaata gatgatatta tactgacgat taaaagggaa aaggaggtag gataattgac
     9841 taagctgagt aaaaaaaata taacttattt gttgatatta gtaagtatag ttgtacttgt
     9901 atttggaatt gtattatcca taactattgg ggcaaaagat atgaatctat caactgttat
     9961 agatagtttg ataaaaatgg aagatggaat aaatatgaga atagtaaagg atgttagact
    10021 tccaagggca atagcagctg cacttgttgg agggttttta gcagtttctg gggcaataat
    10081 gcaaggaata acgagaaatc ctatagctga accatctgtt ataggaatta cacaaggagc
    10141 tacattcgca atttcgatat cactggtact tcaaaaaaaa cttcctcaac ttatacatgg
    10201 aagttttagt gtaatgatgt ttgcatttat tggagcaagt ataagtggat tatttatata
    10261 ttttataagt tctaaatcaa gaggaagagt taataatgta aaattagctc ttgcaggagt
    10321 cgctcttggt acattgctaa tttctttggc atcagcaata tctatgtatt ttaacctatc
    10381 tcaacaatta agtttctgga tatcaggagg gcttgtagga gtgaagtggg aaggtataaa
    10441 attgctattt gtagctggtg gtattggatt tattttagct attattatgg ctccaagaat
    10501 aactatatta agtcttggag aagaagtggc aataggatta ggacaaaaaa ctaactttgt
    10561 tagatttata tgtatagtac ttgtaatatt aatgactgga gcatctgtgt cagtgtctgg
    10621 taatattatt tttataggtc ttatagttcc tcaaatagct aaaggaatag taggttcaga
    10681 ttataagtat ataataccga gctctttagt attaggagct gtattgcttg tatatacaga
    10741 tatattaagt aggatgataa atcctccata tgagacacca gtaggttcta taacagcact
    10801 tataggagtg ccaatattta tataccttgt tagaaagggg gagaaatagg tactatgaaa
    10861 aatattataa aaataaattc taaaacatta cttgttatat caattttaat ggtgcttatt
    10921 tttatcactt ttttattgag tttaaatatg ggctcatttt ctatagaacc aatgaatgtt
    10981 ataaagactt ttttatggca gggtcagcgt aatcatgaaa ttgcaatatt taaattaaga
    11041 ttaccaagaa tagtaatagc acttttggtt ggttctgcat tatcaacagc aggtgtaata
    11101 cttcaaggag ttacaaagaa tgatttagct gattctggaa ttttgggaat aaattcaggt
    11161 gctgcattgt ttgtagtagt ttatatatat cttatgaatg gtaatgtata tgaaggtatg
    11221 agtaacttga ctgtatttac aatgcctatt gttgcactta taggagcttt atttggagca
    11281 tttcttatat attctcttgc atggaaaggt ggtataaatt cgtcaagatt actacttatt
    11341 ggtataggtg taaacatagc ttttacttca attttgacga tattccaatt gaaatttaca
    11401 acacaagaat ttaatagggt tatggcatgg acatcaggaa gcatttgggg aaccagttgg
    11461 aaatatgtaa tagttgtgct tccatttata gtgattttta tgggtataac tatttataaa
    11521 tctaaatata tagatgtttt aaatttgggt gatgaagtat ctataagtct tggtgtagat
    11581 gtagaaaaac aaagaagaag acttataata tatgcagtaa ttttatctgg tgtatcgaca
    11641 gcagtagcag gtagtatttc atttttaggt ttaatagctc cacatatagg tagaaaaata
    11701 ataggaccaa agcataaaag attaatacca gtatcagcat tgataggaac attattactt
    11761 ttaatagcag atactatatc aagaaatctt ctagcaccta tagaaatacc agtaggtata
    11821 gtagtttcta taataggagt gccgtacttt atttatttaa tgttggtaaa tgattaggaa
    11881 agggtgttgt tatgaactgt ataaatacta agaatctaaa tgtatcatat ggaaacacag
    11941 atattataaa aaatttaaat ttaaatatac caaaaggaaa aataactacc atcatagggg
    12001 ctaatggttg tggaaaatcg acaatactta aaactatagg tagaattatt agccctaata
    12061 gtgggaaaat atatataaat ggagaggaca tctacaaaaa gaagtctaaa gaaatagcaa
    12121 aggatatggc tgtacttcca caaagccctc aagctcctag tggtcttacc gtttcagaat
    12181 taatttctta tggaagattt cctcataaaa gtggatttgg taattctagt aaagaagaca
    12241 gagagattgt aaattggagt ttagaagtta ctggaattgc agaatttaag gatagaaata
    12301 tggaagattt atcaggagga caaagacaaa gggcatggat agctatggct ttggcacaag
    12361 aaactgatat attattactg gatgagccta caacatattt agatttggca catcaattgg
    12421 agatactaaa attattagat gaactaaata aaaaacaagg aagaactatt gtcatggtaa
    12481 tacatgaact taataatgca gcaagatttg ctgaccacat gataggtatt aagaaaggta
    12541 aaatagtttg tgaaggtgat gcatatgatg ttatgacgaa ggataatcta aaagaattat
    12601 ttaatattga tgcagaaata gcaacagacc caagaacaaa taaaccaatt tgtataactt
    12661 atgacatggt gtaaatggtg acaacatgga gaatcaagaa gcattaagac atgaaaaaat
    12721 atggatttta ttatttaggt attcgatacc tgcaataata gcaatgatgg taacttcact
    12781 ttataatgta gtagatagag cttttattgg ttctatggaa ggtattggct ctatagctat
    12841 tgcaggtctt ggtgtaacta tgccagtatt tactctaata atagcttttg gaatgttggt
    12901 atcagtaggt gctagcacaa gattgtctat aaagttaggt gaaagaaata gagaagaagc
    12961 agagaagata ttaggtaatg ctttgacatt atctataatt atctctttaa ttataactat
    13021 attaggatta gttttcttag aagatatact ttttattttg ggtgcaagta aagattcaat
    13081 attttatgca aaagactata tgagtgtcat attggttgga agtatattta atttagttgc
    13141 attttctctt aataatgcaa ttagggcaga aggtaatcca aaattagcag caaggacaat
    13201 gattgtagga tgtgtattaa acctgatatt ggaccctata tttatatttg tatttaattt
    13261 aggtataaaa ggagcagcta tagcaacagt actctgtcaa atagtagtat tcttttgggt
    13321 aatacattat tttataagag ggaagtccaa tttaaaacta aaaaaatgta acttaaaatt
    13381 gaataaagat atagtaaaga aggtatttgc aataggaatg acaccttttg ctatggaagt
    13441 agctataagt ataactcaca tgtttacaaa taattctcta aaggtttatg gtggagattt
    13501 agctattgga gctatgacag cacttacatc tattttattg atgtttatga tgcctgtgtt
    13561 tggattgaat caaggtatgc aaactataat atcatacaat tatggtgcaa aacaatatga
    13621 gcgtgcaaag aaaactttaa tattatctat catagtgtca gttgtcatat tgtcatttgg
    13681 atttttagta gtacaagttt tcccagaagt atttgtaggt atatttaata aagattcaga
    13741 tttgatggat atagcagtaa gaggtataag cctaaatcta attacattgc ctataatggg
    13801 gatttctatt gtaggacctg tgtattttca gtgtataagt aaagttaaac attcaatgtt
    13861 tttaactctt ttaagacaat ttattttatt tataccatta atcattgtac ttccaattca
    13921 atttaattta gatggtgttt ggttggcaca gccagttgca gattttattg ctatgataat
    13981 cgtattatta ttcttaaaaa gggaatttaa aacaagccga gtgtaagaaa tttagaaaat
    14041 aaaattaaat tggaaaataa aaagacttgt ctttataaaa tgattaaaat tattttatag
    14101 agacaagttt tttattttat ttaaacggaa ctatccatac tggtttcttc tagttttttt
    14161 ccaaaagtca ttttctcaaa tatttcttga ggtagaggtt ttgaaaaaac atatccttgt
    14221 atcatatcac aattaatttt tttaagataa tccatttgca agattgtttc aacaccttct
    14281 gatatactat tcatatttaa tttttttgcc aaattaacta tagattctat tacatgattt
    14341 tcagcaatat tatctgcatt aggtgagcta aaaaaagcac ggtcaagttt taatgtgtca
    14401 acttttattt cttttaacat attgagtgaa gagtatccac ttccaaagtc atctagtgaa
    14461 cattgaaaac cttcttcatg gatttggtct attatattaa ttaatttttg gagattttca
    14521 aatacaagtg tttcagttaa ttcaatttct aagagcttag caggaatgtt gtatttatta
    14581 cgaagcattc tgtatttttc taaaaaatct atattattta aattagcacg tgaaaaatta
    14641 actgaaacag gtattggagt ttctccatta tctatccatt ttcttatcat actgcatact
    14701 ttttcaaaaa catagtggtc gagttttgta ataaaaccat ttttttcaaa gaaaggaata
    14761 aactcgtctg gtggtataag acctttattt gggtcttgcc atcttactaa tgcttctgca
    14821 cctacaatag tattatcttt gaggcttatt ttaggctgaa gatatactat aaattcgtta
    14881 ttatttaatg cttcctccat tctattttcc atttcttttt ctttaatcat ttttaaacgc
    14941 tctaaatcac tataaaaaac acatgtataa agtggatgat ttccaatgtt tcctttatta
    15001 ttttttcgtg caacatttgc acggtcttga attgaaacta aaggtagatt tgggtcatca
    15061 attttatata cacctataga tagagctata aaatatttac attcttcatt tttattgaaa
    15121 ctattaatat cattggtgat attttctatg tacttaagaa tttctttttg aggaatagtt
    15181 ttaataagta cattaaactg gtcattagaa actcgacaaa gcaattctcc tggttctaga
    15241 taattactaa tgacatcatg tatgtacttt aatgttttat ctcctgcttc actaccaaaa
    15301 gaatcattaa taagtttgaa tttctgaata tttatagata ccaatgaata gctttctgat
    15361 gaagatgatt gtataatttt tttagcttca atatcaaaac gtgctttact gtaaccttta
    15421 gttacagagt ctacataggc gatttttata agttgtgccc tgttcttttg atttataaac
    15481 ataatcaata taataagcaa taaaaatagt ataacaatta aaatattgat gaagattgct
    15541 ttttttagaa gtaaatcaaa ctgtgcactt gctgtttttg ttggaacaat tgaaaggagg
    15601 tataagtttt cttcttgtaa tggaagatag tgcattgcct tagaaatacc atcatttaat
    15661 gtataataca tagaaccagt tttgttcttt tttaagttta ttttcatttc ttcaagttta
    15721 tttttatcaa cctgttttcc ttggtgttta atcatgtcaa aaaaatttac cacatttttt
    15781 ggagcatttt tgtttgctga acttacaata aaatttccat cttggtcgat aatttgggaa
    15841 aatccttcac catgaaagct ttctacactt aataaatttc tcatagtatc aatagtattc
    15901 caagcagcaa cagctccaac aattttatcg ccattgtata gtggtacaga atataaaatt
    15961 ccatatgtac cagattgtga tttaacagga gtaattgttt ctttgccttg aagggctttt
    16021 ctataaaagt cttgtccttt aacattacct gtatctttaa gggcacttac aaaatttcca
    16081 ttagaatcta taatacctaa ccaatcaaat tcaaataatt ttaatttttt tgataagtat
    16141 ctattgactt ctttttcact atcattaatc tcaaaataag tatctcccat agaatatagt
    16201 gtcctaaata tacttttaca tttcacatta attgtagtgg aaataccttg tgaaacttct
    16261 acaagatatc gttctgtttc attatgtgtt actttattta gattcataat aaaagtgaca
    16321 catgttaatg acacgattaa aaggagtgtc aatagtaaag tagctattat ttttttattt
    16381 tttgtgtttt caaagttcat tcttttgttt catcctccat cctttatttg tttacaaata
    16441 agaattctct cagacatatt ataccaaata tcttttcata caaagatatt aaattttatt
    16501 tatcccactt tacatttagc tttatttatg tcttcttaga gattaatcaa gatacgttta
    16561 ttgtttaaat cttattttat aatattttga gtaaaagagg ttaaaaaaag aactgttttc
    16621 aaaataattt tgatacagtt ccttttcagt atagaaaatt tttatagtat tagaaagaac
    16681 ttttagctta tgtatctaca taagtattat atttataaaa gatattttgt tacaatctaa
    16741 aatgtagatg aaattctgta aatgccaaat tctctatgac caagactttc agctttggta
    16801 tgtttaccat tacagacttc tattatttca ttaaatattt cttgacctat atctgctatt
    16861 ttagcaccat ctgttataat tctacctgca tttatatcga tattgtctgg cattttgttg
    16921 tatgtatcac tattcccagt gattttaata actggtgaaa tagggcttcc tgttggagta
    16981 cctctaccag ttgaaaagat tacaatttgt gcaccacctg ctaccatacc agtgatagaa
    17041 tctatatctt gacctggagt atccataaaa tataatcctt ttttatcagg aggtacaata
    17101 tcagcatatt caagagcacc tttgaatggc ttattgcctg ccttatacat acacccaagt
    17161 gacttttctt caattgttga aagtccacca gttttattgc ctggagtagg ttgaccacta
    17221 cgtaaatctt ctcccatagc aattgctctt ttttctacat cacttacaaa tttaagaaac
    17281 ttatctttca tttcttcatc ttcaaaacgg gtagccaaca aatgttctgc accaattact
    17341 tctgtagttt cacttagtat gctacttcca ccttcatcta caagaaggtt tgatgcaacg
    17401 cctattgaag ggtttgaagc tattccactt gttgggtcag aaccaccaca ttcaagtgct
    17461 aatgtaattt cactcatacc aaattcaact cttacttctt ttgacacttc acgagccatt
    17521 ttacttacta tttcagctcc cttagaaact gtttttaatg ttccgccaca ttcctgtata
    17581 acaacgtaat ctaccttttt tcctgttgta gctatttcag atgctaattc ttttgcttga
    17641 ataccatcac atccaagacc aactactaaa actgcggcaa cattaggatt ttttccaaat
    17701 cctattaatg tctttgctgt aagctctata tcagaaccaa tttgacaaca tccatgttga
    17761 tgagggattg ctattgctcc aggcacaagt gatgctattc ttgtagctgt ttcacttgaa
    17821 catacagatg ttggaataat taaaacatga ttacgaatac caaactgacc attttctctt
    17881 aaataaccca ttaatttcat tttaacttcc tcctattttt tatctccacg accacgtgta
    17941 ctttcaatgt tatgtacatg aacatagtca ccagttttta tgtcaactgt tgcaattcct
    18001 ataatttcac cgtatttgta tacaacatca ccttttttta catcttctgt agccatctta
    18061 tgaaagacag gtatattatc atttactatg taagactttc catcaattga aactttttca
    18121 cctttaacta aaggtctgac acatgtaact agattatctt tttcatttgc atgaataatt
    18181 gcattcatta attttacctc cttaagtatt actttacttc aatattttta tttgttttaa
    18241 aaatagattt tttctttttt tctcttttat ctagatagga aactaacatt ggacaacata
    18301 ttgctgtaac aataatagca gcagcaacct gtactgttga aacagctgct attgtagcta
    18361 gagtagggtc tatagctgct aaagcttcag gagtaccagc tgcatttccg gctgttgtac
    18421 ctgtagctgc acctactgct ggatgttctg cacgtataag tttcattaca aagtacccac
    18481 ccatacctgt tattatagta actcctaaac caagtacaac tccaggtagt ccagcagtta
    18541 taatttgatt aaagtttaat gctgctccta aaggaaaagc gaagaaagga attaataatg
    18601 ttgtaccagg tgcaagaaat tctcgtatat cttcatcaag gttaccaagt ataaatccaa
    18661 gtagtattgg tataagtgct gcaaatagtg ctactatagg tacatttgca agtccagtta
    18721 ctccaaaagc aagcattgta aaaaaaggac catcatttag agataagata gatattgctc
    18781 caacatctgt ggagtctcca tattcacctg caagagcagc aaatagacct ccatttgaat
    18841 tagtcatggt agcaactatg gcaagaggtg taataccaat tataccttta ggtccaataa
    18901 atttactaac aataatacct aatactgcac caattataaa ttttgttgct gtaagtacta
    18961 tacctttagt caatggttta ccagcttgtc tgatattgat ttgagctcca ttgcatagac
    19021 aaaatagagc aagtatactc attgcaccag ttttaaataa ggatgttgtg aatcctccaa
    19081 tttcaagagc ttgtggacat actgtattaa atagtgctcc aaataacaag ggacagacca
    19141 taagtcctcc tggtatcttt ttcactgatt ttaagatgtg catctagtat cactcccttt
    19201 catttttata taggtattat aaaagcaatt actatgccaa tatatagagt ttgtatcttt
    19261 agttatcatg attattttta ataatcgatt gaaatgctgt agattactta taattaaaag
    19321 tatgattgac gagaatttca cttacaaaga ttctttttat catataattg tattttttat
    19381 tgaaaacaaa taaacgtctt atgtattaaa attaaacata aaacgttttg atatatatag
    19441 atatgtatta tttttaaaca tcatcttcta tttcttttaa cttacgccat agagtggagc
    19501 gagttatctt tagaatttca caggtttttg tagtatttct attattttcg ttataaattt
    19561 tatagatata ttttttttct aaggttttta aatctaaatt actgcattca aaatcactat
    19621 tatctttatc aactatatta tttgtatatt cattgctaag cttttctaat aaaatcgagt
    19681 caaatgattc cacaataaca gccctttcca tcataccttc caattccctt atattacctt
    19741 catattctcg ttcaagaagt gcctttttaa tatttggagt gataattaaa ggcgttttat
    19801 tgtatttgct tgaatattta tgtataaaaa attctgataa ttttataata tcttcttttc
    19861 tttcttttaa tgaaggaaga tataatgtta gtatatttat tctaaaataa aggtcttgtc
    19921 tgaataaacc attgcgcatc atatttttta agtctttatt tgaagcacag ataattttta
    19981 catctatagg aataacttta tcaccaccaa ttctcataac ttgtttttcc tgcaataccc
    20041 tcaataatcg accttgaagt tcaagaggga tttcacttat ttcatctagg aagattgtgc
    20101 cttcatgtgc tagttcgaat acacctgctt tacctttttt tctagcacct gtaaatgaac
    20161 cttcctcata accaaaaaac tcactctcta ttagagatgg aggtatggca gcacaattta
    20221 cagcaacaaa aggtgcattt ttacgcttac tatagttatg tatactttga caaaatagtt
    20281 ctttaccaac tccagattct ccagtaataa tcataggagt atcataacaa gcatattttt
    20341 ttgcaagttc tatacaatct tttgtctttt tactagcatg aattatatca tcaaaagtgt
    20401 atttagcaga tagacctttg cttaataagc tccttcttat tgtatgttca aaagaactta
    20461 tctccttgct atcttgaaat gttgaaacag ccccttgaat ctgaccatca acaatgattg
    20521 gaactctatt tgtaataatt tttgtactcc ctatattttg tatttcacca atttgaggtt
    20581 ccatagtctc aactacttgt ggaagaactg tgtttgggat aacatctaca acattatgat
    20641 aaagtgcatt ttcttttttt ataccaaata ttttttcagc actcttatta aataatgtta
    20701 ttttaaaatt tttatcaact gttattattc catcatgtac aaaatctgtc atagcttcta
    20761 tctgtaatct tcttttttgt tcatccttgg ttgcttcgag tatttgttct gcttgttgaa
    20821 tggctctaag tatgttttct tctctagatt cgattaatat tcccttacaa ttaagtctct
    20881 taacaatatg tgcaacagtg gtatctccta tatatgtgtt tatacctttc tttctgtact
    20941 tttctatagc atcataaatt tcttcttctt tttcaatttc aatcatagtt attttcttat
    21001 tcaatatttc ttctataata tcgaaaccgt agatgacatt attaaatcca attattccaa
    21061 atggttcatt ggaatttttt acctccttgt agctttttat aatatcataa gcatctacct
    21121 taatttcaac tataggtata ttgtaagtag cttttaacat attgtaagtt ccacctcggc
    21181 ttatgataat tctagtacca tgattaatac ttttttcagc aagaggtata ccttctttta
    21241 gattgccaaa tacaacatca atatttgtat atttgttttt tttaactatg tgaattgatt
    21301 tttcataggt tcctttagtg ggagcaataa cgagtatttc cttcataata attcctccat
    21361 atttcatcaa ataaacttaa atattatctt atgactaaat tttatcagtt atattttaac
    21421 attttacttt atatttaatt ataaataaag tatttttaaa aggaacatta taaaagactg
    21481 tatcaaagtt aacttttaga attataaagt ttcatatttt tacagtcttt taatatataa
    21541 tatctattta tcaaatctat ctactttaaa taatttcata tttttatttt gtttgccaag
    21601 atataattca cttaacatta tacctcctaa tattgcaaag agtataccat ttgctccata
    21661 acctaagcaa taccatagat tgttattttt attatctgga ccaataaaac ctaaattatc
    21721 taaagttgaa gcaaaacaac cacaatattt atattcaact tcaatgtctt ttatatcctt
    21781 aaacatactt ttcaatcttt gttctaaaat atcatacttt tcattggcta aagtttcatt
    21841 ttctatatca tcaaaactta catcttcacc acctataatt aatcgattgt ctttagtagt
    21901 tcttagataa ttatatgggt cacagttatc tctaattaaa atgttgtttt tccaagaagc
    21961 tatgttttta agtggtttcg ttgctatatt aaaagtattt gacttagttg caaaatttct
    22021 ttttgtaaat aaacttgtat tgtaccctgt agctacaatt aattttttac catgaacttt
    22081 gtatccatac gatacttcag cagtaacctt atcatttgat aaatctactt tttttacttc
    22141 tgtattttca tatacttgaa gaccattttt taaacttaca tcaatcaaat ggtgactata
    22201 tttatatggg tctaattctc gtcctccatt ctttgctatc aatcctgatt ttaaatcaaa
    22261 gctaaaaggg tttgtggatt catcaatata ttcaacatca aatccatttt cttttcttaa
    22321 gttatattct tctttgatag ccttaacttc aagtttgttg gcagtataaa gtagagtatc
    22381 tcttttggca taatcacact tatttccata tagctctata aatgtatcta attcttcaag
    22441 tgctgaagta caaaggttgt atgcttttag agcatctttt agagtcataa cctctgttaa
    22501 atctatcaaa ttgtcatcta attcatactg taatagagaa gttgtcacgc tagtgcttcc
    22561 atgtgcaatc cttccttttt caagaatgac agactttata ttgtttttag ctagatagta
    22621 agcacaaata catccagtta cgccaccacc aacaattata acatcagtat caatatcatc
    22681 agtaaggtat ggaaattgtc ttggaacttt attaatatta gtaaaaatag gatttccttt
    22741 tacatattct tgattcatat acttcactcc taaaatttat tatgtatgag tgtattattt
    22801 tctatagcaa ataatattat acattttaat tatctagtta tatgggtatg tatagataaa
    22861 atgtgataac attttagtat aaaacatatg tataatatat tcataattac cttattttaa
    22921 gtaatatagt atataatgtt tgttaacaag taaaaagatt gaataaaagt taattaaaaa
    22981 tttaaagtag gaggtaaatt tatgctttca aaaaatatag cttctaaggt attagaaaaa
    23041 tgtctaatta ctggaggaga ttttgctgag atttttgaag aagacactat aaataattct
    23101 attagtttaa tagataataa agtagaaaat gcaataggtg gaagaaatta tggtatagga
    23161 ataagaatat ttaaaggatt gaaaagtata tatgcttata caagtgacaa ttcattaaat
    23221 agtctgttgg atgtagcata caaagctgct gttgctttag gtaaattgga agatggaaaa
    23281 agtgtaatat taaatgacag tattaaaata aataacatac ataatataaa aatttatcca
    23341 aattcaatag gaaataaaga taaagtaagt gttatgaagg ttgcatataa gagtgcaaaa
    23401 gaatttagta atgatatatc tcaagtaagt gttagttatt tggataaaga ccaaaaaata
    23461 ttaattgcaa acactgaagg tatatatgtt gaggatagaa gaataagaac tagactaggg
    23521 ataagttcaa ttgcatctaa gggtaatgaa aatcaaactg gatttgaagg ccctggaggt
    23581 tgtaaagggt ttgaaatatt tgaagaaata gacccagaat attatgcaaa agaatcagcc
    23641 agagtagcgc atactatgtt gcatgctaaa aattgtcctg caggtaatat gatggtagca
    23701 atagataatg gatttggtgg agtaatattt catgaagctt gtggacattc tttggaagct
    23761 acatcagttg caaaggggaa ctctgtattt gcagataaat taggtcaaca gattgcttcc
    23821 acaaagatta cagctataga tgatggtaca ataccaaact actggggttc tatgaatata
    23881 gatgatgagg gaaatccaac tcaaaagaat atactgattg aaaatggaat tttgaagtct
    23941 tatatgatag ataaacttaa tggtagacga atgggaatga atcctacagg aagttctcgt
    24001 agacaaaact acaaatttgc accaacttca aggatgacta acacttatat tgctgctgga
    24061 gaagatagac cagaagatat tataaagtca ataccagatg gactttatgc taaaaaaatg
    24121 ggtggtggtt ctgtaaatcc tgtaacagga gagtttaatt ttgcagtttc agaaggttac
    24181 ttaataaaaa atggagaaat acaagagcca gttagaggtg ctagtttaat tggaaaaggt
    24241 agcgatatac ttatgaatat agatatggtt gggaataacg taaaacaagc tcaggggatg
    24301 tgtggctcat catcaggaag tataccaact aatgtaggcc aacctatgat aagggtaaaa
    24361 gaaattactg taggtggaag ataggaggga taattgtgga acttaaaaac tttaaagata
    24421 tattatttaa aaaggctcta agtgaaggtt ttgaagagtg tgaaatatat tattatacag
    24481 gagaaaattt aagtataaat atatatgaag gagaagttga gaaatacaat cttgataaat
    24541 cttttggttt atcttttaga ggtaaggtaa atggaaagat aggttattct tatacagaaa
    24601 ttttagatga taaagctgtt gatatgttga taaaaaatgt aaaagatgga gtaaacacta
    24661 ttgaaaatga agatgtacaa tttatatatg aaggagataa gcactataat gatgtaaaga
    24721 cttattctaa agagctagaa aatttagagg cagataagtt gattgattta gctttagaaa
    24781 tggaaagaga gactaaagct tattcagata aggtggtaaa tttatctaaa tgtactatat
    24841 cttattctgt atcaagtaat ggtatatcta atactaaagg tcttaattta agcaataaaa
    24901 ctaatatgct tatagggttt gtagttccta tcatagaaga caatggacaa aaatatgatg
    24961 gaataggata taatatagca aattctattg aagaaataaa accttgtgag atagcaaaac
    25021 ttggtgttga taatgcttta tctaaagtag gtggtaagag tattccatca ggtaaatata
    25081 aaactatatt gcttaatgaa gctatggtat ctttgcttag cacattttct gggatattta
    25141 atgcagattc agctcaaaaa ggattatctt tattgaaaaa tagagaagga gacatgatag
    25201 catctcctat agttacaata gttgatgacc cacttttaga aaatggtatg gcatctactc
    25261 cttttgatga tgaaggagta gctacattta aaaaagaagt tgttttaaat ggaaagctta
    25321 taactttact tcataactta aaaacggcta ataaggcagg tgtaaagact acaggaaatg
    25381 gaataaaatc ttcatattca tcacctataa gcatatatcc aactaatttt tatatagaga
    25441 aaggagataa atctttagat gaaattataa aggatataga tgaagggttg atggttacta
    25501 gctttgcagg gcttcattca ggtgcaaatt cagtaacagg agacttttct ttagctgcca
    25561 aaggctttta tatcaaagaa ggaaaaaaag tatttccagt ggagcaaatt acagtagcag
    25621 gaaactattt tgacctgttg aaagatattg aagttatagg ggaagattta gaatttccaa
    25681 tgagtagtat aggttcacct tcagttgtta ttaaagagct atcagtagct ggaaaagatg
    25741 aataattaaa aagtaatttt gtggataaaa ggtcatgtta attttaatta atatggcttt
    25801 ttattattta agtagatttt attatctaag ttatatgaaa aagttgtgat gcatacaatt
    25861 aatatcatac attaaattta aaggaggaga tattatgagt ggtgcacatt atgacatgca
    25921 caagcgaaat ggatattcaa gtgatgagcc atatccagag ataaaagttt taggtccaaa
    25981 taagtattat gcagaattat tgatggatga ctatgctgga gtatcaagtg aatttacgag
    26041 tgtaaatcaa tatctatacc ataattttga tttagatgaa acgcatagag agttaagtga
    26101 aatgtggata aatatatcta taacagaaat gttacatatg gagatattag caaagactat
    26161 aagattattg ggtggcaatc ctgtatatag aggttctaca agttcttgtg gtgcatattg
    26221 gaatggtggt tttgtatgtt atggaaattc tatttgtaac agattaaaac tagatttgca
    26281 tttggagcat gtggctatta atcattatta taaagatata agtcttattg aagaccctta
    26341 tataaaagct atattaaata gaataatcct agatgaaaaa cttcatgtaa gtttatttga
    26401 aaaggcaata gagaagtatt gtaaataaat ttgaaaattt agttattcat cattttattc
    26461 atatatataa aataaccatc atacattttc ttgaagggag ttgctgttga tatgtattat
    26521 gtatatgtga atgatataaa catagcagta tatgatttga atccgagtgc taaaaaaact
    26581 gtacttttta tacatggttg gcccttagga cataagatat ttgaatatca aacaaatata
    26641 ttgccaaaac tcggatatag aacagtttca attgatttaa gaggttttgg taaatctgat
    26701 gcaacatcag gaggatatac ttatagccaa ttagcagacg atatttataa ggtggtacat
    26761 gctattggat taaaagactt tacccttgtt ggtttttcaa tgggaggagc aatcgtactt
    26821 aggtatatga gtttatttaa tggatatgga gtgtcaaaat tggtattagc tgcagctgct
    26881 gcaccatcat ttgtacaaag acctccagaa tttccatatg gtatgacacg tgaagatgta
    26941 aataaattga tagcacaagc atgtactgat agaccagaaa tggtaaccga ttttggcgaa
    27001 aaagtatttg catcaaatcc accagaaagc tttagaagat ggtttaatga tattggtttt
    27061 agtgcatcag gtattggcac tattggaact gctgtatctt taagagatga agaattattt
    27121 aatgatttaa aatgtgtaag agtgcctact ggtatatttc atgggaaatt agatgaaata
    27181 tgtccgtatg aatttgcagt ttttatgaat gaaaaaatag aagattcaat tttatatact
    27241 tttgagtata gtggtcatgc tatattctat gatgagctta aactatttaa tcaggaattt
    27301 ttacagtttt tagaggaata gatatatttt attatcactt agaaaaagag taatattatg
    27361 tgaaaagatt taagctaaat tttatgatgt tttttacact aaacaaatag ggttttagaa
    27421 cttgtaacta agttctaaga ccctattatt atatattcct aaaatttgtt ataatttatt
    27481 ccttgtcatt cttaaaatgt attaatatat taacgaattt atattaaatt tttgtttata
    27541 ttccaataat gtcaaactaa ccgttttaga aattaaatta tatgtgaaaa aagatagctt
    27601 acattatttt attatggaaa ataatagtaa atggtacaaa atttgatttt taagatttaa
    27661 aactttttta aaaagtgcta caatagacca aattattact ttctatactc gttaaacagg
    27721 aggtgggact atgaaaaaac ataatatttt atttgtatca actgatgaca aaataaatat
    27781 agatatatca aaacaattgg aaaatatatt tggagaattt tgtaatatag ataacttggt
    27841 atatgtaaat aggataaata ttgaactgtc aagctatgag cttgtagtat gttcagacaa
    27901 tgatataaag gaatatatac ataataatat tgataaaaat atacctattg taatagtaca
    27961 tcgtactata aatattgaaa atataaatca gataataagt atagaaaatg attctgatgt
    28021 tatggttata gatgcttata aagagtcagc agatgaaact gccaagataa ttagaaaact
    28081 aggattaatt catattaatc taataccata ttatccaggt tgtgataagt ctaaatgtga
    28141 gattggaatt attacgggaa gcagaaacag cataccacaa aacataaagc aaataattga
    28201 cataggtgat aaggtaattg atataaatac agttatagaa atctttacaa aactaaatat
    28261 atctatagat aaactacata ttattaagga aaaatacaat gaagatacag taagtggata
    28321 taggtattat acaactatga ataaaaccat gaagagtttt ttggagatta tagatgaagg
    28381 tattgcttct gttgataaat taggaaaatt tatatattgc aacaaagtat tttctaatct
    28441 agttggaata gaccaaaatg aaattatatc taataacttt atggacttat ttagtgataa
    28501 ggttgtcaaa aaaatatttt ttcaagaaga tgaagttaat gatgaagtag taaatttaaa
    28561 taacaaaaaa ctgataatta ataaagtaaa tgtttatgaa aataatgaac gaataaagag
    28621 tattataagc attaaaaata taagtgcaat tcaagtgctt gaggacaaga ttcaaaataa
    28681 acttcagtca aaaggttttg tatcaaagta tacatttgag agtgttgtag gtgagagtaa
    28741 aataataaaa gaaaaaatta atattgcaag aaaaatagca actacagact tttctgtgtt
    28801 gatacttgga gaaaatggaa caggaaaaga aatatttgcc caggcaatac ataatgaatc
    28861 tctaagaaaa aacaagccat ttgttgcagt taatctatct tctttgtcag atacacttat
    28921 tgaaagtgaa ctttttggct atgatgaagg aagttttaca ggagcaataa aaggtggaaa
    28981 aatgggtata tttgaaagag cacacacagg aacaattttt ttagatgaga taggtgatat
    29041 atctttagat gtacagcaga gattgctaag agtattacag gaaaaagaag ttatgagaat
    29101 gggcggaagt aaaattatac caatagatgt tagaattata gctgcaacaa ataaagattt
    29161 aaagaaaaaa attaaagaag gttcctttag agaagatttg tattatagga ttaatgtatt
    29221 acatatagag atacctagac ttagagaacg taaggaagat atacctctta taagtaagta
    29281 ttttttagat gaaataaata gcaacaaatg ttttacagag gaatcaatgc aagctttaac
    29341 attgtatgaa tggccaggaa atgtaagaga gcttaaaaat ttaatttatt atattgatac
    29401 tatagttgag gaagatagag tagattacga gcatttgcca gaacaattta gatttgaaaa
    29461 aaaaaatact ttagttaatg aaaatttcga ttcaattatc ttagatttca aacaatctaa
    29521 tttctttgag gaaagtatat gtatattgac cagtatagaa acttggaata ataaaaatat
    29581 attattagga agaaataaac tgcaagagat tttaaaagaa aaagatatag ttttaagtgt
    29641 agaccaaatt agaaaaagaa tagataagtt aaagagccat ggtttacttt tatctggagt
    29701 aaaaaaacaa ggtagtttta taactgatga aggaaagaac tttatatcat atgtaaaaat
    29761 taagggagtg atatagggga ctaaaaaggc aaaacaccct aaaaaaatcc ctataatgga
    29821 tagaaataaa taaaattatc tttaagatta agataattca aaaatattga ataaataatc
    29881 taagaagatt atttttaata aaacagtagt aaatatcaac cttaccactg tttttatttt
    29941 ttgcaagatt tattatacaa ttaaaattta tattttggca cattaattgc tacataggaa
    30001 aaatataaaa aattgtagaa cttggagggt gttgttatga agtcagctta caaaggatat
    30061 gaagcctata gttatttaga aaaaggaaaa gatatttcat ctattgagat gtgtaaagga
    30121 gataaaagag ttaaagagta ccttattgaa ttagatgata ttcaagaagc gaaggttaaa
    30181 agtatagtgg atgaaaaaat atttatatca ttacatgaac atccagtatt atttccagaa
    30241 cacctagaaa gagatatatt tgaatataat agggaaggta aacaaagatg cgcttatgaa
    30301 gcattatcaa gaggatatta tgatgctata tttgataatt taatggatgg tgtatgtacg
    30361 ataacatcaa attcagggtg gaaatgggat gatatattaa tagatttagg catgagacta
    30421 tgtgatttag ctcatcaaga ttttgtcata aagtgtgaaa aagtagaaga tatatacaga
    30481 gctaaaagtg aaggtaaagt agcattgata ccaacattag aaggtgcagc accaatagaa
    30541 aatgaacttg acagaataga tatactgtat ggatttggta taaggttaat gggtataaca
    30601 tacagcgaat ccaatgcatt aggttcaggg ctaaaagaag agaaagatgg aggtcttaca
    30661 aatttcggga aaaaagctgt tgaaagaatg aataaaattg gaatggcaat agattgctct
    30721 cacgttggag ttcaaactac acttgatgta atagagtata gcaaggaccc aataatatta
    30781 agccatgttg gggcaagaag tttatggaac acaaagagac taactccaga tgaagtatta
    30841 atagcatgtg ctaaaaaagg aggggttata ggtgtagaag cagcacctca tactacaata
    30901 acagagaaga ataaagaaca ttcaatagag tcatttatgg aacattttga gtatattaaa
    30961 aatttagtag gaatagacca tgtagctttt ggaccagata cagtatatgg cgaccatgta
    31021 aaattacact cagtactagc tgctaaattt gatataaaaa aaataacagg tacaaaagaa
    31081 catcccaaag tagaatatgt aaaaggtctt gagaacccaa cagaaacttc aaaaaacatt
    31141 gtcagatatt tagtaaagca tggatatagt gatgaggaaa tagagaaggt actaggtgga
    31201 aatatactta gagtactaaa acaggtttgg aaatagatat attagaaata ttaataaaat
    31261 ttgaggattt atagggaggt tttataaatg gattatttaa aattagctaa tcatccactt
    31321 ttgtggatag cgagtacagt agcagtatca atagtagtgg tacaatccct tatatttgct
    31381 ataaaatctt gcaaagttgg taaaacaatg ggaataacag ataaacaaat aaagtcagct
    31441 gttaagagta gtgctatttc agctattggg ccttcaatga ctatatttgc tggaatggta
    31501 tcgcttatag taactatggg tgggcctata gcatggatga gattatcatt tataggttct
    31561 gtaatttttg aatcaatgtc agccggattt ggaacagatg cattaggtat aactttaggt
    31621 tctcctgaaa tgacaaaact tgcatttaca aatgcagttt ggactatgat attaggttct
    31681 ttaggatgga taatattcac attactattt ggacataaac tagataagat aaccaatgtt
    31741 atatctagtg gcaagaaatc atttatacca ataatatctc taggagcaat gttgggttca
    31801 tttgcatatc taaatgctga tagggtgttg cgttttgata atggaacaat tgcatgtata
    31861 agtggaatgg ctataatggt aatattgtgt atgcttgaaa agaagaaaaa tataaaatgg
    31921 ttaagagagt gggggcttac aatatcaatg tttagcggaa tgataatagc ttcagtaata
    31981 taagggggga gttagtttta tgagtaaagt aaaatctata tacaatgaag aatatttacc
    32041 ttttatgata aggtatggaa gattaacact atctttgggt attatagcag cattagttcc
    32101 tggaataatt ttgagctttg gatttggtat tatgcctcca atatcagcat tattagcaag
    32161 tacaatggca attgtcagta tgagtgctcc aaattacata atagaaccag tttcttattc
    32221 accaatctta ggtataccag gaacttatat gagttttctt tctggtaata tatctaatat
    32281 gaggctacca tgttcaatag cagctcaaaa ggcagcagaa gttgaatcag gtacagaaga
    32341 aggctcgata atatctacaa taggaatagc tgtatctatt ttagtgaata taagtatact
    32401 aactataggg gtaattttag gaggaagcgt actatctaaa attccagctg aagtagtaga
    32461 aaaattaaac ttaattttac cagctctatt tgggtcagtt tttggacaag tatttttaca
    32521 agataaaaaa ttaggtctag tagcaattgt aatatctgta ttgactatta tattatcaaa
    32581 gcaaggtata ataccacagt ctctagtagt tcttatatgt gtatttggta ctatattaat
    32641 tgcaagagct atgtataaag ataagcttag tgactaatta caatgaaata atagtgaatt
    32701 ttcaaatatg aaatttaata atttgatttt caaatataaa aattacatta agattattta
    32761 aaaattggtt tttaaggagg gaatattttg atatatgatt taatcttaaa aaatggattt
    32821 ataatagatg gtacaggtaa tcctggtttt tatggagata tagcaattaa agacaactta
    32881 atagcaaaaa tagattctaa gataaatagc aatataaata aagagattga ttgttgtgga
    32941 aaagttatga cacctggatt tattgaccct catgttcatg aagaaatagt agcaatacta
    33001 gatggtaaat ttgaaaagtt tctaaaacaa ggagttacaa caactataaa tggtaattgt
    33061 ggacattcta taacaccata ttcttctgaa aatgtgtatg aatatatgta taaaaatggt
    33121 ctattacttg aagaagaaaa aaagtatctt atagataaaa ataaatgttg gaataatttt
    33181 acagaatatt gtgaccttat atctaaaagt ggtatttctg tcaatatggg attcttgttg
    33241 gggcatggga ctataagatg gagtgttatg ggaggttcta aggatagaac tcctacagaa
    33301 aaggaaaaaa atgaaattac agatataata aatgatggaa tgaaaagtgg tgcttttgga
    33361 atatctactg gattggcata tataccaagt aagtatgctg atattgatga acttgttgat
    33421 attgcaaggc agattaaaga gtatgatggt atatatacat ctcatattag agattacata
    33481 ggaagatata atgcagtaaa agaagccata gaggttgggc aaaaaagtgg tgctagggtt
    33541 caagtatctc acttaagtcc agttgaaata gaagcatttg atgagatatt aaaggctagg
    33601 tataatggtg ttgaaataat ggttgacaca gtaccaagaa gttctgggca ttgtatgaag
    33661 aaaaaaagag taattcaatt tattatggca atatcatcta gtctatttga attaggtata
    33721 gatggggtaa tggatgctct tagaaatgaa gagggaagaa cacttatatt aaaagaagca
    33781 tttatacttg gagatagggg gagtataata cttctaaaca ctaaagatat taatatggaa
    33841 aagaaatcaa tacgtgaaat agctacacaa aaaggaatag atgaggacaa gttattactc
    33901 gatttacttt tagatggaga cgaagaactt atcttttgtt taggaggaat gtatagagct
    33961 gatttcccag ataaactaca tgatgataaa ataattgata atccatttgt tatggttggt
    34021 tcagattgtt tgtttagtgt gggtggggat atgtcatggt ttgaactaca aagaagagga
    34081 gcttttccaa ttttcttcaa tatgtacaga aagtctggtg ttagattgga agagattgta
    34141 agaagagtta cttcattacc agctaggcaa tttaaaataa aaaatagagg tattcttaaa
    34201 gaagggttga tagctgatat agcagttatt gacatggata actatagtta ttctaggtca
    34261 gaagatattg atttttcaaa gccacaatta ctagccaatg gtgttgaata tgtaattgta
    34321 aatggaaaaa ttgcattgga aaatggagag attactgaga ataaatgtgg tgaagtatta
    34381 aaaagataag gttttaaaaa taataggatt tagaaagtaa ataaatatct aagtaagtaa
    34441 agacgaagtt tgagatttat ttaaataaaa atcatgcttc gtttttattt atagtattaa
    34501 tatttatttt aataatcaga taatatttgt actttatagt gaaaaaatta atatttttaa
    34561 tcattaaatt atgtaaaaaa ttggataaat agataactaa atcatttgag aaaagatttt
    34621 tagaaataaa aaatgataac taaataaccc ctttaatatt tatcaaatag ccagtcataa
    34681 atattaaaag gggttattta gtttataaaa attatttgta ataaagtagg atatattaat
    34741 aaatatgata gaatatatat tataaattaa atttataaat ataagggggg aactttgagt
    34801 tcttatagat ttcttacatt ataagaacca atactttatg cgggagttat taaaagtaac
    34861 acttatagta atgcttgttt tgataaatgc tttttttgta gcttgtgaat ttgctatggt
    34921 aaaacttcgt agttctagga ttgataccat gataactgaa ggtaataata atgcaaaaag
    34981 atgtaaaata ataaaagaca acttaaattc ctatctttct gcatgtcaac ttggtataac
    35041 actttgttca cttgcattag gttggatggg agaatctaca gttaaagagt taattttacc
    35101 aatagtaagt gtatttaatc ttagtgaaag tattatatat actatatcaa tttccatttc
    35161 ttttttaatt ataacaatga tggaggttgt aataggagag ttggttccta aagctttagc
    35221 actttataat acagaaaaaa taatgttgag tacatctttt ttattagtag gattttataa
    35281 gttaacatat ccaataatat attttttcaa cttaagtact gatttatttc ttaaaccatt
    35341 tggatattca caagctgatg aggttgatga accccataca ggtgacgaaa taagactatt
    35401 agtagaagaa agttataaaa gtggacttat agatgaatca gagcaaagat tagttgataa
    35461 tatttttgaa tttgaagaaa agaaaattag agagataatg gttcctagaa ctgatatggt
    35521 atgtatatat gaaagtgatt ctgaagaaaa gatattagct attttaaaag aggaaggtgt
    35581 tacaagatat ccagtatgca gaaaaaataa agatgatata ttaggttttg tacatataag
    35641 agatttatac aatcaaaaga taaatgaaaa taaaattgaa ctagaagaaa tattgagaga
    35701 tattatatat atatctgaaa atttaactat agataaagct cttgagagaa taagaaagga
    35761 aaaacttcaa cttgctatag ttgtggatga atatggtggt acatctggtg tggtaacaat
    35821 agaagatata ctagaagaga tagttggaga aattcaagat gaatttgaca aagaagagac
    35881 tcatattaag aaaataggag caggttctta cttagttgat ggaactgaat ctatcaacta
    35941 tattaataag tattttggac ttgatataga gcatgatgga tttgacagta taggtgggtg
    36001 gatatcctat atgcttggtt caaatattaa agtaaaccaa agtgtaactt ttgaaaatta
    36061 caattttaca atattagaat tggataaatt gagggttgta aaattaatca taaaaagtgt
    36121 aatataatta tatcaaaaaa tattggagga attgtatgca aaaagtagaa ggaattattt
    36181 ttgacatgga tggagttttg tttgactcag agagaatttc tcttgaattt tggatggaga
    36241 cgtttgaaaa gtatggatat actatgacta aggaaattta tacatcagtt atgggaagaa
    36301 atcgtaaagg aataatagaa ggtcttacag atatatacga tagttctgta ccaataatag
    36361 atttatatga cgaaaaaact aaaaacatga ttgaatttat ggagaggaag ggagctccta
    36421 tcaaattagg agtcaatgaa ctaatctctt ttttaaaaga aaatggatac aaaatggctg
    36481 ttgcaacatc aacaaagaga gaaagagcag taaagagatt agctaaggca aatttaaaag
    36541 attactttga tgctatagtt tgtggagatg atgttgtaaa ctctaaacca aaccctgaga
    36601 tattcttaaa agcagctaaa aagataaatg ttaatcccaa aaattgtatt gtcatagagg
    36661 attcgcctat gggagttgaa gctgcataca atggtggtat aagatgtata aatgtaccag
    36721 atttaaaaga gccagatgag caaattaaat cacaatcaca taagatactt gaaaatttac
    36781 tggaagttag agaataccta aaaagtttga actctaaaga atgtcacaat ctataatata
    36841 aagtattaat taaataaatt aaatataatt tctttgattt agaataaatc catgaatatg
    36901 agaaaaaata agtataaaca gctaggagga atattcatgg ataatgtagg ttctctatta
    36961 tattttttat ttaatttttt cttgtatggt tttataggtt ggataattga aaacttatat
    37021 agttattata aacaagggca ttttcaagaa gatggatttt taaatggtcc atttaaacca
    37081 atgtatgcaa ttgcaatgtc gattataata gaggtctcaa gatttattga ccccaataat
    37141 atatttgcat tgcttttatt atgtctagta gtgccgacag tagtagaata tattacagga
    37201 atacttatga aagtatattt taataaggtc tattgggatt attcagatta taagtacaat
    37261 agtagaggaa tagtatgtct aaagttttct gtatattgga ctatattgac atttattgga
    37321 gttagatatt ttcaagtgta tatagttgat agtttatata gtcttataat accttattgg
    37381 ccaattgttg taactatact tttagtaaca ttgtttgtgg atgaaattct tactataaaa
    37441 tttttgaggg gaaataaaga tatagtagaa agataacttt aaaaatatga gttgaattta
    37501 gattgtagtt aaaagaaagc tatgttaaaa tggtgaaatc atttaaaatt agctttcttt
    37561 tttatttgat aaaattattt tataatatat ctataagttg taaagttttt tattaaaatt
    37621 aaaataaagt gtagaaaatg gggagtgatt tatgatgggt aaaataagat ttggtattgt
    37681 tgggacaagc aatatagcaa atatatttct aagagctgca tctagggtta aagactttga
    37741 attggttgct gtatattcta gaaatttaga aaaagctaga gaatttggaa ctctatatgg
    37801 agcaagtatt ttttttgatg atttagaaca aatggctaaa tcgaaggata tagatgctgt
    37861 atacatagct tctccaaatg cattacattc aaagcaaacc attacttgtt taaaacacaa
    37921 aaaacatgtg ctttgtgaaa agtcgttagc atctaattta aaagaagtca aatcaatgat
    37981 aaaaacagcc aaagataata atgtattgct tatggaagct atgagaatta catgtgttcc
    38041 aaactttaaa gcagttaaag aaaacttata taaaataggg aaaataagaa gattttttgg
    38101 aagctattgt cagtattctt caagatatga taaatataaa aatggaatta tagaaaatgc
    38161 ctttaaaaaa gagttatcaa atggagcttt aatggatata ggagtgtatt gtatacatcc
    38221 tatggtgaat ttatttggcg ctccaaaaac tgtaaaggca gtttctcata tacttcaaac
    38281 tggagtggat ggagaaggtt cagctgtatt tcaatatgat gatatggatg cgataattca
    38341 gtattctaaa gtagctgatt cttatatacc atctgaaata caaggagaag agggaagtat
    38401 aataattgaa aagcttaatc tatttgaaaa agctattatt aaatacagag atggaagaga
    38461 agaagatata tctattccaa aagaaaaagc agaggaaaag cctagagaaa tagaaggaat
    38521 gtattatgaa cttgtagagt ttataagtct tataaataac aataaaatag aatcaaatat
    38581 aaattctcat gaaaattcaa taatagtaat ggaaattatg gatgagataa gaagacaaag
    38641 tagtattgtt tatccagctg atagtatata gtttatatta gaaaatataa gaatttataa
    38701 tatatattct taaataaatt taattttaag ttaaggtaag gtgtatactt agccaagtgt
    38761 taaaatgtca aattataagt atgaaaaagt gctaaaaaga aatttatttt tggcgttttt
    38821 ttcttttttt ttacaatttt gtaacagtat caaaaaaagt tttgacgatt ttattacaat
    38881 tttgtagttg aatatacata tcaaaactaa tatgattaat aataacataa atttgaatat
    38941 ttttagagga gagaaaatat gagaaaattg atatacttta ttacaccttt tataataggc
    39001 gtagtatttt tatttgggtt agacaaattt cttgattcta aaactgatga acttttgagg
    39061 gagaaaaatc tacttccaat tatggatgat actttaagtg atataaaaga taaaggggtt
    39121 acagcaaata atcatttttt aagagaaaag gatattatga ttttggggtc atcagaactt
    39181 agtaattcaa caaaacaaca tccaaagtac tattttaata caaataggag taaaaataag
    39241 gtgtttgcaa ttgggagagc ctatactcag acattacaag atgctgcaat attaggaagt
    39301 atgaatccta atattgataa taagaaagtt gtcttgttaa tttctatgca atggtttatg
    39361 gaaaaagacg gagtcacaag tcaccattat cagtctagat tttcaccaat acaattttat
    39421 cgatttttag ataatccaaa aatatctaaa caaaataaga ttgaatatgc aaaaaaatca
    39481 agtaagttat tatggggaag tgatgagtat aaagcagaag cattatatgc taagctatat
    39541 gagcctaaga catttcctga aaaagctgaa aaggtgcttt tagagcctta ttttcaagga
    39601 agaaagtact gtatagctct taaagaaaag ggtattcttt ataaacgatt aattaagcta
    39661 gataaaaaga gagcaacaaa aagaaaaaga ccaataaatt ggtcatatga gagaaagaaa
    39721 gccattgaag atgctaaaaa aagagttggt aaaaatccac taaatattga taagtactat
    39781 tataaagagc attttaaaga tggtatagag caatacaaag gaagagacaa agatgtaaat
    39841 ttattaacat ctaaggagtt tgaaaattat aaactgatgc taaatgtatg tactgactta
    39901 ggtattaagc cagttgttgt attaatccca agtatggata aattctataa tttgactggt
    39961 atttctgaaa aagaaagaaa tcagtactac gataaagcac aaaaaatagc agaaagcaaa
    40021 ggctttgaag ttctaaacct taaagataaa gggtcagata agtattattt aagggatgta
    40081 atgcatcttg gtacgaaagg atgggtagat gtctgtgaga gattatttaa aatatttaaa
    40141 gaacaataaa gatttgttaa ctagtatttg tttaactatg gttataatat tggcgatagg
    40201 agttctaaca tttactccat ttaaagaatt gccatttatt tataacggat tttaaaggag
    40261 cattcttata tgaaaattat tgaaggaata aaaaaatatt caaatacaga tagaacagca
    40321 ctaatgtgta atggagataa actttcttat aaagatttaa atgaatattc agatgctata
    40381 tcagtatttc taaaggatgt atacaaagaa gaagatactc ctatagtaat ttatggaaat
    40441 aaagaaaaca tgataatggc atgtatgata ggagctttaa aatcaggtag agcgtatgtg
    40501 cctcttgata ttagttttcc aattgataga gtttttgaag tcactaaaga gataaaacca
    40561 aaggtattat ttaactttag tgatgaaaga aattttggag atatcaatgt aattgatatg
    40621 gataaattaa attatataat aaatgaatat cagggaaaat cattagataa agaaaactgg
    40681 gtaaaagatg atgaaaatgc atatatacta tttacttcag gaagtacagg aaagccaaaa
    40741 ggggttcaaa taagttcaaa caatttagat agcttttcag attggataag cccatatcta
    40801 aacatagatg gaagtgaaaa agtaataatg aaccaaccag catattcttt tgacctttca
    40861 gttacaacaa tataccctgg tcttatccat ggagctacat tattttcaat atcaaaagat
    40921 gtattagcag actataaaga actatttaga caatttagta tctcagatat agctgtatgg
    40981 gtgtcaactc cttcttttgc aggagtatgt ataactgaaa aagagtttaa tagtaaaatg
    41041 cttcctaacc ttgagtcaat gatattcata ggagaagcac tttcaaaaaa tcttactaaa
    41101 gaacttatga gtagatttcc aaacacaaga attatcaatg gatatggacc aaccgaggct
    41161 actgttggtg taagtgtaaa tgatatgact caaaaggcta tagatgatga aaaaagtctt
    41221 ccagttggat accctatgtc aaattgtaaa ataaaaatac ttgatgaaga tggaaatgag
    41281 cttaaagaaa atgaaaaggg tgaaattata ataattggac catcagtttc taaaggttac
    41341 ttcaataata aagaaaagac tgatgaagta tttttctatg atgaaataga tggtgtaaag
    41401 tggagagctt ataaaactgg agatatggga tatcttttag atggaaatat atattattgt
    41461 ggaagaaaag attttcagat taaattaaat ggatttagaa ttgaaataga agatatagaa
    41521 aataatttga gaaaagtaca taatgtaaaa aatgcagtag ttttaccagt atataaggac
    41581 gaaaaaattg cttacttaaa aggtattgtt gagttaaatg aaaagaatga tttaagtaat
    41641 attaaaaatg ggatgataat aaaaaaggaa cttggaaagt atataccttc atatatgatt
    41701 ccaagaaata tttcaataat ctctgagttt ccaacaaata tcaatggtaa aatagacaga
    41761 aagaaactta tggaggaaat ttaatgattt tttcacaata tggagattat ttttatcttt
    41821 atatattatt attaacatca ataccagcag taattttagg tctaatgggc aagaatataa
    41881 agtattatgg tatgttggca agtttgttta tgatattctt aatagtagga attgatgtcc
    41941 aactaaagta cttggtaata tttattattc ttgaagtaat aatagttaaa ggatatgaat
    42001 atgtaagaag aaaaactaaa aataaataca tatattgggg attcttgttt gcatcaatgc
    42061 tcccaataat aataaataaa atatctccag ttacttcttt tggaataatt ggatttattg
    42121 gaatatcata cttaaatttc agaactatac aaatggttat tgaaatttat gatggagcta
    42181 taaaagaagt taaaatttca aagatgcttt attttatgtt attttttcca actttaagtt
    42241 ctggacctat tgataggtca agaagatttg aacaggactt ggaaaaacaa atctctagaa
    42301 aagagtatat agaagaatac ttactgccag gaataaaaaa tattgtcatg ggagtaggtt
    42361 ataagtttgt tatagcattt ttgataaata catattgggt atcaagaata cctaaagata
    42421 tgagttttat aaatatttta agttatatgt acgcatatag tttatacctg ttctttgatt
    42481 ttgcgggata tagtttattt gctataggta cagggtacat atttggaata caagtaccta
    42541 taaactttga caagccattt atcagcaaag atatgaaaga gttctggaca agatggcata
    42601 taagtctttc aagatggttt ggagattata ttttttctag atttgttatg tcatcaatga
    42661 gaaagaaaag atttaagaaa aggactactg ctgctcatgt ggctcagatg ataaccatga
    42721 taacaatggg attttggcat ggtctaactt ggtattatgt tgcttatggt gtataccaag
    42781 gattggcact tgtgttaact gatatatatc agcgaaaatc taaattttat aaaaaacata
    42841 aaaaagataa atggttcgag agagtgcaga ttttcattac attccatatt gtgtgttttg
    42901 gattgctgat attctcaggt tatttagctt aattttaagg aggaaaattt atgcaagaaa
    42961 cagttataga aatatttgaa gatgtattag gaactgatga gataagagaa gatttagacc
    43021 ttaatttatt tgagacggaa cttttagact cattagctat aattgaagtt ttacttgaaa
    43081 ttgaaaatag attagggata gagcttcaac caactgattt agagagaaaa gatatgtcta
    43141 ctgtaaataa tttagtaaaa ttcttggaga caagaaaata aattagtagt tagactttaa
    43201 atattaattt ataaaataaa attttacaaa gtccatctga tactaatatt tgatggactt
    43261 ttttaatgat aatacaaagt cttttgaaaa taactttaat taagtaaaaa atttaataca
    43321 taaatatgat ttcataaatc ttaggtatca ttgtaatatt ataggagaaa aatatattat
    43381 atttaggagg aaaatgaatg tctttaaatt cgatagatag aaaaaaagaa atacttaaat
    43441 tattagattc aaaagggaag gtaaacacta aagaattagt aaaaagatta gaagtatcat
    43501 cagaaacaat aagaagatat ttggaagaat tagaaaatga aaataaatta aaaaaggtat
    43561 atggtggtgc tataaaaata aattatggag tgattgaacc agaacatata aagagaaaca
    43621 atactaacct agataaaaag caaagtattg ctaaatatgc agctaagttt gtaaatgaca
    43681 atgagtcaat tatcatagat gaaggtacta ccaatttgca ggttgtagat tatataatat
    43741 ctgtaaacaa tttaaaaatt attacaaact cttatccagt tctatcaaaa ttgatttctt
    43801 atgagaatca aggtttgttt gatggagaag ttatatttat tggtggaaaa gtaaatttaa
    43861 aacaccaaag gacagcatgt ccaatgtcaa tagatactat gaaaaactta tacgtagata
    43921 aagcttttat atctagtgaa ggtatacttg atagttttgg aattagtagt atagaccaaa
    43981 ataaggcatt gttgtcaaaa gaatatataa aaaattcaaa ggaaagtttt gtattatgtg
    44041 atagttctaa aataggaatt gctagtatgt ataagatagc agatttagag gaattagatt
    44101 ttgttatttg tgatgtagaa cctccgaatg aatggaagga taagttaaat gagataaata
    44161 taacatggat agaagcaaaa taaaccctta gttttatata atacaactat gctcaataca
    44221 actaaattca taaaatatag tcagttcata gattaagatt agaaagtaaa ttttagattg
    44281 taacttagga ttttatggga atatgataca aaataaaaac aactaaatac aactaaaaac
    44341 agaaatttaa tatatattta acctaaatat gatgtataat taacatatga aagttatact
    44401 ttaaaagtaa aaacaattaa aaacacaaaa attctaaaaa gaatctatgg aggctataaa
    44461 tatgaaaaag atatatggag aaaaaataaa agcagtagta ttcgattggg ctggaacaac
    44521 agtagattat ggatgttttg cacctcttaa tgtatttata gagatattta aaagaagagg
    44581 tatagatgta acaatggaag aagcaagaaa acctatggga aaattaaaaa tagaccatat
    44641 aagagaaatg tgtgaaatgg atagaataaa aaatctttgg tcagataagt ttggtaaagt
    44701 gccaactgaa gatgatgtaa atgaacttta tgctgaattt gagccaatgt tatttgagac
    44761 attagaagat tatacgactc caattcctca tgttgttgaa actattgaaa agttgagaaa
    44821 aaatggatta aaaataggtt ctacaacggg ttatacaaga gagatgatga acatagttga
    44881 accaaatgca gcaaagaagg gatactcacc cgattttctt gtaacaccat cagaagtatc
    44941 tcaaggaaga ccgtatcctt ggatgtgcta taaaaatgct gaagctttag gggtgtctcc
    45001 tatgagttct atggtaaaag taggagatac aataagtgat gtaaaagaag gcgtaaatgc
    45061 aggaatgtgg agtgttgctg taataaaagg ttcaagtgag ttagggctta cacaagaaga
    45121 agtagagaac atggataagg aagaattaaa agctaagatg agtatagttt caaagaaatt
    45181 taaagaggca ggtgcacatt ttgtaataga aactatggct gagttagaag atatactaat
    45241 aaaaatagag aatgaaacta ttaaatcaga ttttgtacca gaaaatgatt acatattact
    45301 tacaccagga ccactatcta ctactaaatc agtaagagca tctatgttaa aagattggtg
    45361 tacttgggat gttgaatata ataacctagt acaagatgtt agaagaagat tagtatctct
    45421 agcaacccaa aatacagata aatacacaag tgtattaatg caaggaagtg ggactttttc
    45481 agtagaagct ataataggaa gtactatttc aaaagatggt aaacttcttg taattgcaaa
    45541 tggagcatat ggaaagagaa tgaaagatat atgtaattat cttaacatac aatttgttga
    45601 ctgcacattt aaagatatag aagcagtgga tttaaatgta gtagaaaatt tattaaaaga
    45661 aaacaaggat ataacacata tatcaatggt tcactgtgaa actactacag gtagattaaa
    45721 tcctatacaa gaggtaggga aacttgcaaa agaatataac aaaatttata tagttgatgc
    45781 tatgagtagt tttgggggaa ttgagattga tgttgaatat tttaatatag attttttagt
    45841 tagtagttct aacaaatgta tacaaggagt acctggattt ggttttataa tagctaataa
    45901 agagaaatta tctaaatgta aaggtatagc taaatcatta tctcttgatg tgtatgcgca
    45961 atgggagact atggagaaaa ataatggtaa atggagattt acttcaccta cacatgttgt
    46021 aagagctttt tatcaagctt tattagaatt ggaagaagaa ggttctgttg aaaaaagata
    46081 tgctagatat aaagaaaatc agtttacaat agcttcaaga ttaaaatctt taggatttga
    46141 tactttggtg aatgataatg ctcaatcacc tgtaataaca actttcttat atcctaaaaa
    46201 tgcaaagttt gaatttatgg aattttatac ttatttaaaa gataatggat ttgttatcta
    46261 tccaggtaaa ttgactgata tagatacatt tagaataggt agcataggtg aagtttatcc
    46321 aactgatatg gagagactag ctgatgtaat agaaaaattt atcaatagat agaagaagat
    46381 agtgtcttgt aggttacaga atagtgcgga aagcccactc ctttaggtgt gtgagatgat
    46441 agcacaaaca gtgtataaaa agtattgaca gtagaattta aagacttata ttttagaagt
    46501 ttatacaatg aatatataaa gattgagtaa tagggatata ttttatttaa accacaatct
    46561 aagaaattag atttctagtt taaataaagc atttccctat tatttttatg cctatttata
    46621 gaaaataaat gatagttgct ttattaagta ttattatcac acttgacaac gtaacaatgt
    46681 tttgttatat tgggtttaaa gataaaatac ggtaaagaaa ggatatcatt atgaatgaag
    46741 aattaagttc actaagattt gatggtgttg gaaaatgtaa aggtggaatt tttgataatg
    46801 ttaatatatc aggaacaggc aaaatagaag gaagtgtaaa atgtagtaaa tttgattctt
    46861 ctggttcagc aaaagttttt gggacaacag aatgtaatga attttttaca tctggtttaa
    46921 gtaaagtaga aggaaacata ctggcatcaa aagttgagat atcgggactt cttagatgta
    46981 caggaaatat taattctgtt gaaattgata ctagtggaat tattaatgta gaaggaagta
    47041 taaaatcgga tattattcat ggagaaggat atttaaaagc aaatgagaat atagattgtg
    47101 aaaatatcaa tttaagtgga atcttggagt gtaatggatt tttgaattgt gaagaagtta
    47161 atattagttt aaatggaact tctaatttta atgaagttgg agcaagtagt gtaaatataa
    47221 aaaaggggca tggagattat tgcaaaaaat ttcgtatgct agaaaaaaag catatcaact
    47281 ttgaaaaagt gtcttcaaat ttaataagtt taggtctatt atcaattaga aagtatacag
    47341 aaagtaaatt gtttgcaaat attatagaag cagatgaaat aagcttagaa aatagtgaag
    47401 tcaaagttgt aagaggaaaa aatattaaaa taggcaaggg atgttatgta gaaagtttgg
    47461 agtacagtga aagtatagag attgatgaag attcaatagt tagtgaaata aagaatataa
    47521 gtgaaaaaat aaaattaaag aaggataagt aataagtagg tttaaaaata aaatttaaaa
    47581 tgaggtaata atatggaaaa agggtctata aaaatacttg gagaaggctt tataagtagt
    47641 ggtgagtatg aaaatataaa aatcgtggga agctctaaat caaaaggaaa tgttaaaagt
    47701 aacgaagtaa aagtccttgg agatgcaaaa tttgaaggtg acatcaatat aaaaaatttt
    47761 gttgttaacg gaaaaactat tataagaggc aatcttaaag cagagcgtgt aagagtgaat
    47821 ggtcaactta atatagaggg agatgcagaa atagatgact tagttataac tgctcaacag
    47881 aaagtggatg gcaaacttaa atgtaataat gttacaataa gaggacaatt aagtgtaaat
    47941 gaaaatatgt atgcacaaga tataaaaatc tatggcgaaa tgagaaataa atcaaatata
    48001 gaatgtgaag atataaaggt atatggagca ataaaatgtg atggtctttt aaatggagaa
    48061 aatatatatg tttattcagg aggaggttct tattgtaaag agataggggc aactaatata
    48121 aaaataggaa gaagcaaaga tgctttttca ttaattaaaa tcattaatat tttttcagga
    48181 aagtttaaat gtaatttgat agagggagat actattgaat tagaagatgc atcaataaaa
    48241 gatatacgag gcaaaagcat atctctagta gataattgtg acgttgtaaa tattgaatac
    48301 agtgataatt tatcagtttc agataattct actgtaaaaa acagtataaa ggtgggctag
    48361 aaaagttatg gaagaattaa tatctaagaa agatttattg agcaaaacta atatatctta
    48421 tggtcaatta tatagatgga aaagaaaaaa cataatacca gaggaatggt ttataaaaaa
    48481 atcagctttt acaggtcaag agactttctt tccaagagat aaaatactag aaagaataga
    48541 gttaatattg tctatgaaag aagagacttc tcttgatgat attgcaaata tgtttatgaa
    48601 aaaggatatt aataaagaat ttgacattga ttttattctc agtaaagaag ttatatgtaa
    48661 ttataccaaa gaaatatttc aaaatttata taaaaaagag caaagcatag gtaaaaaaga
    48721 actgcttata ttgagcataa tagagaagtt tttagttaaa tctataataa cttttgaaga
    48781 gttaaaattg atagtgaata taatagaaga aaattttaca tcaatataca atgaaagtgg
    48841 aaagatttat ttgtttagaa agtttggagt tccattcgta gtaggatgtc tggattataa
    48901 aaaagtaaag tttgaaaaag atgtagttaa gattattgag gttgacttga caaaagaaat
    48961 aaatgatata agtataaagt tatcatagtg tattatctta tataatgtat tataataata
    49021 tacttaaaat acactttatt taaatattta gtttaaagat aagattttat gtgagtgtgt
    49081 aaaagttaaa gatagattta agtaggttat agggattagt aaacaataaa atgaaccatg
    49141 atgaactact ataaattgta tttaaactac attttctact tatagtaata tcaatggttc
    49201 attttattgt tattaagata atacagtatt tataaaaata cttgatataa atatagtaaa
    49261 ttgtttaaat agaattattg ccttaattta ttcaaataat gagtttttaa aatctaagaa
    49321 atatccttgt ggatgaaggc atacaggaca agcttttgga gcttctttac ctatatgtat
    49381 atggccacaa tgtgtacata tccattgtat atcttcattt cttctgaata aagtaccttc
    49441 ttctaaatca gtagcatatc taccaaatct atcaccatga actttttcta tttcagctat
    49501 attttcaaat aacttagcta tagattcaaa tccttcttca cgtgctgttt ttccaaagtt
    49561 tttatataca tcatcccact cttgaagctc attatgttgt gcagctttaa ggtgttgtgc
    49621 tgtcttgtca tataaatcta cagggtatgc tcctgatata cttatatttt caccagcaaa
    49681 ttcttttaat ttagaaaaga attgttttgc atgtgatttt tcttggtcag cagtgtaatt
    49741 aaataaagac tctattatat ataatccttc tttttttgct acagatgcag aaatattgta
    49801 tctatttcta gcttgactct cacctgcaaa agctcttaat aaattttctt tagttttact
    49861 atcttttaaa ttcatattct acctctctat cacaataaat ttttacaata tttgattctt
    49921 tttatttatt attccaatag gagatataat tatgctcaat ttagtcagca tttttaaaat
    49981 tatcattaat tttttttaaa attctaagaa attcttgttt ttcattttct gtaatattat
    50041 gatatgccgt ctctttaact tgtgttgaga tgctattaaa agtatcttct ataagcagtg
    50101 ccttttttgt aagctttata tacgtgatac gtttgtcatt tgtacatttt tgtctttcta
    50161 aatatcctag gtttataagt ttattaacca acactgtaac agtggattta tcttttccta
    50221 ttttagctgc aatttctttc attgtaagta ttccattatt ttcataaagt gcagttaaaa
    50281 tatttccatg agtaggtatt aactcaccta aaccattttt actgagttta ttttcaatga
    50341 atttaatcat actagccttt gttttactta tgaaatgtac aatatattta tcttccataa
    50401 attattctcc aatctttaat ctatttaaat tagtttgaca taaaactatt tataaactat
    50461 aattagttta acataaaact aaatgtattg ggaggaaatt tatgaataaa aaatttaaat
    50521 cactatatat tacagaagaa gaaggaaatt ttagaagaaa tatagttgaa agagaagtgg
    50581 atacattgcc agaaggcgaa gttttaataa aagtaaaata ttcttcttta aattacaagg
    50641 atgcactttc tgcaaatggt aataagggtg ttacgagaaa gtatcctcat acaccaggaa
    50701 ttgatgcatc tggtatagta gaatctagta gttgtgatga ttttaaaatt ggagaagaag
    50761 ttttagtaac aggttatgac ttgggaatga atacttctgg tggtttttca gaatacataa
    50821 gagttccttc tagttgggta gttaaacttc ctaaaaatct ttcactaaaa gaagcaatgg
    50881 attatggtac agcagggttt acagcagctt tatctgtgta taaatttata gattctgtag
    50941 acaagaatat gggagatgta ttagtcactg gtggtactgg aggagttgct gtaattgcaa
    51001 ctaaaatatt gattaaatta ggttattcag ttgtagtttc aacaggaaaa ttagaagaac
    51061 aaaaagaagt attactaaac ttaggtgtta aagatgttat acataggtca gaagtggatg
    51121 ataactcagg aagacctctg cttagaccaa gatgggctgg agtaatagat acagtaggag
    51181 gaaatactct agcaacagca ataaagacaa ctaattattg tggagcagta acaacttgtg
    51241 gtaatgcagg aggagttgat tttacaagtt cagtatatcc atttatatta aagggaatta
    51301 ctttatatgg tatagattct gtggattgcc caatgaactt aagattaaaa atatgggatt
    51361 tattatcaaa tgaatggaaa ttagatgatt tagatgatat ggtaaatgta gtatcattgg
    51421 aagagttaaa tgatagtata gattcaataa tggcaggaaa acatgttgga agaacagtag
    51481 ttgatttaga aaaaatatag gtgaataaat ttataattag gattataggt tttaagcaaa
    51541 aatgagatac ttgaaattta cttatgagta tctcattttt ttatgtaaaa agatttatgt
    51601 agatgtttgt gtaaaaagat tattcatgaa caattaattc aaatacatct ggtcttgaat
    51661 agtgaccttc tgaatcaaaa tctagtctac taagtactat tttttctagg tctaaatcag
    51721 ctattagcat ttcttcttta ttgaaaatag gacctgctac atattttcca aaagggtcaa
    51781 ctatacaact tcctcctgga cacataattt ctggttctgc atctagctct ttatagtagt
    51841 taaggtcagt tggatacata tttttttcaa catattgatt gcatccaatt acaaaacatc
    51901 ttccttctaa agcaatatgc ttcatagttg cttgccactc ttctcttgaa tctgcagtag
    51961 gggctatgta aagttttaca cccttagcat aaagagctgt tctagctaat ggcatataat
    52021 tttcccaaca aatcaacgaa cccatttttc catatggagt atcaactact gtaagagtac
    52081 ttccatctcc ttctccccaa atacatcttt ctgttcctgt aggtttaagt tttctgtgtt
    52141 taccaattag cttaccttct ggagagaaaa ataagtttgt gcaataaagg gtacaattta
    52201 tatcattacc atctctttct gttataccca ttgatagata tactcctgct tcttgtgctg
    52261 cttttcctaa taaatctgtt gtagcactag gaactggtac agaattatca tagtatcttt
    52321 tccaatcttc tctaccttcc attgttctac ttccaacaac aaatccaaat gaaagacctc
    52381 ttggatatgc aggtatgaat gcttcaggga aaactacgat atttgcccct tttctaccag
    52441 cttctttaat taatcctaat gctttttcaa cagttttttc taaatccatt atgactggtg
    52501 acgcctggac aacagcaatt cttacatttt tattttcctt gctcataaaa aacctcctaa
    52561 aaaatattta aattttttgc attgaataga ttacatgaga tgttatttga gaactaagat
    52621 acttatattg tgaataataa tgtaactgta tatttaaaat aatacatcat gatttaaaaa
    52681 attacaattg tacagatata attgagttta gatatttaaa tttaacaact tataatattt
    52741 tttcaattag tataaagcct attaatttgt cttatttaca atgaatagta tttacttctt
    52801 ggcaaacaat aattaaaaat aaaactttta tatgattaaa ctctaaagaa aaagtttata
    52861 aagaagataa tataattaag cagaaaataa tgaaaaaaat ttattaaagt agacaacgta
    52921 aggagaattt tatgaaagca aaaatttatt acaatggaaa tatcatcaca atggaagatt
    52981 caatatgtgg agatgctatt cttataaaag acaaaataat aaaaaagata ggaacaaaag
    53041 aagaagtatt tgctttgaaa aataaagata cagaaattat agatttacaa ggtaagacat
    53101 tgatgccatc ttttatagat tcacatagtc acttgatagc ttttgctact actctaaagc
    53161 tagttccttt agaagatgca accagtttta aagacatagt aaaaaaaata caggatttca
    53221 aagagtcgaa taatataaaa aaaggagact ggataattgg attttcatat gataataatt
    53281 ttttagaaga aaataagcat ccagataaga gtgtactcga tagtgcatct tcagaaaatc
    53341 caatactaat ttcacatgct tctggtcata tgggagttgc aaatacattg gggttaaaac
    53401 agcttggtgt taccaatgaa acacgtgacc cagaaggtgg acatataggt agagtagaag
    53461 gcagtgaaga accaaatgga tatttagaag aaaatgcatt ttttaatgta gcatctaaaa
    53521 taaaacaacc atcatcaaat gagattttta attcaattga aaaagcacag aacatatatc
    53581 taagctatgg tattacaaca gctcaagaag gtttaatgga agaaaatcaa tttaacattt
    53641 taaaagcaat ggcaaatcaa aataaattaa aaatggatgt tgtaggatat gtaaatttga
    53701 aaaaaagtaa gtctgtagca gataataata gggagtttat aaaaaaatat ataaatagat
    53761 ttaaaatagg aggttataag attttcttag atggttctcc acaaggtaag acagcatggt
    53821 tgagtagacc atatgaaaat tcagatgatg gttattgtgg atatcctata tacaaagatg
    53881 aagaagtaga aaagtttata gatatttcac taaaagaaaa gatgcaacta ttaactcatt
    53941 gtaatggaga tgcagcagca gaccagttga tagatgcgtt tgagaaagtt ttaaacttaa
    54001 aagagcaaag tagtgaaaat catataagac cagttatgat acatgctcaa acagtaagag
    54061 aagaccagat tgatgatatg aaagtaataa atatgatacc ttcatacttt gtagctcaca
    54121 catattattg gggtgatatt catatcaaaa accttggaga agatagagcg tttaagatta
    54181 gcccacttaa aacaactata gaaaagggat taatttacac tcttcatcag gatacaccag
    54241 taatagcacc taatatgctg gaaacagtat ggtgtgctgt caatagaatt acaaaaaaag
    54301 gtatacaaat aggagaaaat gaaaagataa gcccattaga tgctttaaag ggtgttacta
    54361 taaatgcagc atatcaatat tttgaagaag ataaaaaagg ttcaattaaa gaagggaaat
    54421 tagctaattt gataatatta gatgaaaacc cacttacaat cgaccctatg aaaataaaag
    54481 atattaaagt attgcagact ataagagaag gggaagtatt gtattctttg aagtagatga
    54541 aagttagata ttttataatc tataaaaaat agttttatat aataagttag gtagaattaa
    54601 ataagattac agttaaatca acaattatat ttttattaaa ttttaattat tgtattgaag
    54661 atttataagt ataattttat tgattctacc tttttaaata actgtcgatt tattaaagtt
    54721 atctatgtac tatattaaac aattaagtag ttattaattg aacttattag tttattaaaa
    54781 aactatgtat attactttgc agtaagactt tggaactaaa tctataatag caaatttaaa
    54841 tttattaaat agattacctt ataacatttc atataaaata tattgtgaat ctcagaaaat
    54901 tactattttt ctttgagtat tttttgtaag cagttctaaa agattcaatt tcatacctat
    54961 tacttgaatc attcatcaaa ataattctaa tttaaaaaat aattctatcc aaataataga
    55021 tatataggac tatgtt
//
LOCUS       DAEPUT010000019        53785 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.019, whole genome shotgun sequence.
ACCESSION   DAEPUT010000019 DAEPUT010000000
VERSION     DAEPUT010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53785
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.019"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            178..1491
                     /locus_tag="KRL22_001259"
     CDS             178..1491
                     /locus_tag="KRL22_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1271761.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            1663..2838
                     /locus_tag="KRL22_001260"
     CDS             1663..2838
                     /locus_tag="KRL22_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBH1271762.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            2941..3960
                     /gene="hrcA"
                     /locus_tag="KRL22_001261"
     CDS             2941..3960
                     /gene="hrcA"
                     /locus_tag="KRL22_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HBH1271763.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            3990..4610
                     /gene="grpE"
                     /locus_tag="KRL22_001262"
     CDS             3990..4610
                     /gene="grpE"
                     /locus_tag="KRL22_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBH1271764.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            4702..6549
                     /gene="dnaK"
                     /locus_tag="KRL22_001263"
     CDS             4702..6549
                     /gene="dnaK"
                     /locus_tag="KRL22_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBH1271765.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            6760..7914
                     /gene="dnaJ"
                     /locus_tag="KRL22_001264"
     CDS             6760..7914
                     /gene="dnaJ"
                     /locus_tag="KRL22_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBH1271766.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            8880..9815
                     /locus_tag="KRL22_001265"
     CDS             8880..9815
                     /locus_tag="KRL22_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH1271767.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EGLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            9851..11224
                     /locus_tag="KRL22_001266"
     CDS             9851..11224
                     /locus_tag="KRL22_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1271768.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(11412..12179)
                     /locus_tag="KRL22_001267"
     CDS             complement(11412..12179)
                     /locus_tag="KRL22_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1271769.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(12209..13318)
                     /gene="ugpC"
                     /locus_tag="KRL22_001268"
     CDS             complement(12209..13318)
                     /gene="ugpC"
                     /locus_tag="KRL22_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBH1271770.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNNIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            13576..14313
                     /gene="cas6"
                     /locus_tag="KRL22_001269"
     CDS             13576..14313
                     /gene="cas6"
                     /locus_tag="KRL22_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH1271771.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILSAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLGSIRGSGLRKPLEFIPINFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            14318..15793
                     /locus_tag="KRL22_001270"
     CDS             14318..15793
                     /locus_tag="KRL22_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271772.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLMYVNFI
                     EELDKSSATAKQKEDIKKDFKNRRFPYVRNSGKYGLNTSLKNMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     GNTRNLGKRMIDNGNLSNLKELLLDNISVLKQSTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            15813..16826
                     /locus_tag="KRL22_001271"
     CDS             15813..16826
                     /locus_tag="KRL22_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HBH1271773.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYKGSTQLITNRGFLSSEFGRKYYDEKEENEVPR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVIGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            16842..17639
                     /gene="cas5"
                     /locus_tag="KRL22_001272"
     CDS             16842..17639
                     /gene="cas5"
                     /locus_tag="KRL22_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HBH1271774.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYIKMGKGKDKEKFLLKGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVKLKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            17666..20074
                     /locus_tag="KRL22_001273"
     CDS             17666..20074
                     /locus_tag="KRL22_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBH1271775.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKNILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSTSKVQKEIYDYIE
                     KGILEKEDFNLEDIEDYIKEILYVDFKFNEDVLDYDYIDKLSESMVIDSDYNNGQIED
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGENDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKSILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            20515..21462
                     /gene="prmA"
                     /locus_tag="KRL22_001274"
     CDS             20515..21462
                     /gene="prmA"
                     /locus_tag="KRL22_001274"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBH1271776.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            21481..22239
                     /locus_tag="KRL22_001275"
     CDS             21481..22239
                     /locus_tag="KRL22_001275"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBH1271777.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            22241..23539
                     /gene="mtaB"
                     /locus_tag="KRL22_001276"
     CDS             22241..23539
                     /gene="mtaB"
                     /locus_tag="KRL22_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HBH1271778.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            23582..23932
                     /locus_tag="KRL22_001277"
     CDS             23582..23932
                     /locus_tag="KRL22_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HBH1271779.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            24095..24274
                     /locus_tag="KRL22_001278"
     CDS             24095..24274
                     /locus_tag="KRL22_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBH1271780.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            24304..24747
                     /locus_tag="KRL22_001279"
     CDS             24304..24747
                     /locus_tag="KRL22_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBH1271781.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            24858..25355
                     /locus_tag="KRL22_001280"
     CDS             24858..25355
                     /locus_tag="KRL22_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBH1271782.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            25548..26111
                     /gene="raiA"
                     /locus_tag="KRL22_001281"
     CDS             25548..26111
                     /gene="raiA"
                     /locus_tag="KRL22_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH1271783.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            26324..26560
                     /locus_tag="KRL22_001282"
     CDS             26324..26560
                     /locus_tag="KRL22_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HBH1271784.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            26573..27916
                     /gene="yqfD"
                     /locus_tag="KRL22_001283"
     CDS             26573..27916
                     /gene="yqfD"
                     /locus_tag="KRL22_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HBH1271785.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKDFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            27855..28970
                     /locus_tag="KRL22_001284"
     CDS             27855..28970
                     /locus_tag="KRL22_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBH1271786.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            29027..29488
                     /gene="ybeY"
                     /locus_tag="KRL22_001285"
     CDS             29027..29488
                     /gene="ybeY"
                     /locus_tag="KRL22_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBH1271787.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            29494..30213
                     /locus_tag="KRL22_001286"
     CDS             29494..30213
                     /locus_tag="KRL22_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBH1271788.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            30332..30733
                     /locus_tag="KRL22_001287"
     CDS             30332..30733
                     /locus_tag="KRL22_001287"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBH1271789.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            30797..31690
                     /gene="era"
                     /locus_tag="KRL22_001288"
     CDS             30797..31690
                     /gene="era"
                     /locus_tag="KRL22_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBH1271790.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            31702..33081
                     /gene="mgtE"
                     /locus_tag="KRL22_001289"
     CDS             31702..33081
                     /gene="mgtE"
                     /locus_tag="KRL22_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBH1271791.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            33154..33309
                     /locus_tag="KRL22_001290"
     CDS             33154..33309
                     /locus_tag="KRL22_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HBH1271792.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            33275..34048
                     /gene="recO"
                     /locus_tag="KRL22_001291"
     CDS             33275..34048
                     /gene="recO"
                     /locus_tag="KRL22_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBH1271793.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            34041..34640
                     /locus_tag="KRL22_001292"
     CDS             34041..34640
                     /locus_tag="KRL22_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HBH1271794.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            34800..35678
                     /gene="glyQ"
                     /locus_tag="KRL22_001293"
     CDS             34800..35678
                     /gene="glyQ"
                     /locus_tag="KRL22_001293"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBH1271795.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            35678..37744
                     /locus_tag="KRL22_001294"
     CDS             35678..37744
                     /locus_tag="KRL22_001294"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBH1271796.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQNDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFDKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKIKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(37910..39457)
                     /locus_tag="KRL22_001295"
     CDS             complement(37910..39457)
                     /locus_tag="KRL22_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HBH1271797.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKILHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DTFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            39737..40504
                     /locus_tag="KRL22_001296"
     CDS             39737..40504
                     /locus_tag="KRL22_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH1271798.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTIHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            40787..40984
                     /locus_tag="KRL22_001297"
     CDS             40787..40984
                     /locus_tag="KRL22_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1271799.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            41013..42089
                     /gene="vorB"
                     /locus_tag="KRL22_001298"
     CDS             41013..42089
                     /gene="vorB"
                     /locus_tag="KRL22_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH1271800.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            42092..42811
                     /locus_tag="KRL22_001299"
     CDS             42092..42811
                     /locus_tag="KRL22_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH1271801.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            42824..43363
                     /locus_tag="KRL22_001300"
     CDS             42824..43363
                     /locus_tag="KRL22_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH1271802.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            43520..44578
                     /gene="buk"
                     /locus_tag="KRL22_001301"
     CDS             43520..44578
                     /gene="buk"
                     /locus_tag="KRL22_001301"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH1271803.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            44596..45489
                     /locus_tag="KRL22_001302"
     CDS             44596..45489
                     /locus_tag="KRL22_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH1271804.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            45519..46727
                     /locus_tag="KRL22_001303"
     CDS             45519..46727
                     /locus_tag="KRL22_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1271805.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTSE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            46751..48010
                     /locus_tag="KRL22_001304"
     CDS             46751..48010
                     /locus_tag="KRL22_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1271806.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            48655..50118
                     /locus_tag="KRL22_001305"
     CDS             48655..50118
                     /locus_tag="KRL22_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH1271807.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            50174..51310
                     /locus_tag="KRL22_001306"
     CDS             50174..51310
                     /locus_tag="KRL22_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1271808.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            51546..52661
                     /locus_tag="KRL22_001307"
     CDS             51546..52661
                     /locus_tag="KRL22_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBH1271809.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            52813..53682
                     /locus_tag="KRL22_001308"
     CDS             52813..53682
                     /locus_tag="KRL22_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1271810.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
BASE COUNT        21360 a         5606 c         9821 g        16998 t
ORIGIN      
        1 agataaaata aataattttt agagaatatt ttagaagtta cgattgtatg atttttaaat
       61 gcataggcat ttactctagg actatagact aatataaaaa aaaactttgg gaatactaaa
      121 accataaatt tataaaatta atattttata tactgtaaaa cagtgaggag ggacagtatg
      181 catactcaac tacaaaagac tattggtctt tcagcagctc tttctactgt tgtaggtatg
      241 gttataggtt cgggagtttt ttttaagcca caagcaatat acactacaac taatggagct
      301 ccaggtctag gtattatagc gtggctttta ggtggtttta taacaataac tgctgggctt
      361 acagctacag aaatttcagc tgctatacca aaaactggtg gtatgatgat ttatatcgaa
      421 gaaatatatg gagaaaagtt aggtttttta actggatgga tgcaaactgt attatttttc
      481 ccaggtacat cagcggcatt aggagtaata tttgctcaac aagcatctga acttttagga
      541 atgagcccaa ataatatggc aaatgtactt cctatagcaa ttggagttat actattttta
      601 gcgttattaa atataatagg ttcatcctta ggaggaaaag ttcagacagt agccactatt
      661 ggaaagatga tacctttaat tttaataata gtctttggat ttattaaagg tcaaagtagt
      721 gaagtattaa atccatttgt aggagatggt gtaaatgcat caaatgcact tggacaagta
      781 ttaatagcta ctttgtttgc atatgatggt tggataaatg ttggagctat atcaggagaa
      841 atgaagtctc cagagaaaga tttaccaaga gcaatagttg gtggtttatc attagttatg
      901 gcagtttata ttataataaa tatagcttat ctttgggtag taccagcaag tgaattagca
      961 acagttactt ccccagctac attagtagca acaagattgt ttggaaatat aggtggaaaa
     1021 gtaataactg tgggtatatt aatatcagta tttgggacat tgaatggata tttattaaca
     1081 ggttcaagga taccttatac attagctgaa atgggaactt taccagcatc taaaactctt
     1141 ttaaaagtaa attctggagg ttctcctgta aattcaatac tacttataac tgtgttagcc
     1201 tgtgtatatg cattatctgg tcaatttaat cttttgacag acttaacaat attttcaata
     1261 tgggtatttt atgtattgac ttttataggt gttatgaggc ttagaagaca aaagccagat
     1321 ttacacagac catataaagt ccctttatat ccaataatac caattatagc tatattaggt
     1381 ggactgtttg taataataaa tcaaatattg acttcaacag tcatatcttt aggcggaata
     1441 tttataacac tattaggttt accagtttat tattatatga aaaaaagata actacttaat
     1501 ttaagttaga taaatttggg taaaggtgaa aattaacttt tatccaaatt ttttatactg
     1561 ttatacaata taagtattat atattgcttg atgtgctatt ttgtttgatt tataatttag
     1621 taattgatgt tttaagataa tttaagaaat gaggagtgaa agatgctagg actttatgta
     1681 catattccat tttgtgtgaa aaaatgtaag tattgtgatt ttaattctta taaaatggac
     1741 atagattcaa aaaaaagata tatagaagac ttaaaaatag aaatggaatt atatagtaat
     1801 aaattatata aagataataa atataaaaat aaagaatgct gtagtctaaa taaaaatgac
     1861 aaaataacga gtatatttgt agggggaggt acacctagta tactaacctc tgatgaaata
     1921 agagaagtat ttataagtat aaaagaaatg tttgatatag atgagaatgc agaaataact
     1981 atagagtgta atcctgggac attaacatta gaaaaattaa aaactatgaa agagattggc
     2041 ataaatagac ttagtatagg gctacaagct attcaagaaa agcatttgaa ctttatagga
     2101 agaatacata cttatgaaga atttgagaaa aactataaag atgcattaag tgtaggtttt
     2161 aaaaatatta atatagattt aatgtacagt cttccaaatc aaactctatg tgattggaag
     2221 gaaactcttg aaaaagttgt acacttaaat ccaacacata tatcagctta ttcccttata
     2281 ctagaagaag gaactgaact atacaatatg tatgaaagta ataaatttga acttatagat
     2341 gaaaatgtag atatagaaat gtatgagtat acaataaact acttaaagtc aaaaggatat
     2401 aatcaatatg aaatatccaa ctactcaaaa gaaggctata attgtgagca taatatttta
     2461 tattgggaat gtgaacatta tatagggatt ggagcaggag cttctggcta tattaatgag
     2521 aacagataca ataatgtaga atctttagaa gattatcatt taagtttggt aaaaagagaa
     2581 aaaccaatac aagaaaatga aattctttct gagaaagata tgatagaaga aaagatattt
     2641 atggggctta gaatgaataa aggcataaaa tttgaagatt ttaaaaaaaa atttggaata
     2701 gattttagag agaagtataa taagcaaata gaaatgctat tagctagaaa gcttataaat
     2761 cagagctttg aaggtataca attaactcaa aaaggaagag aaatatctaa tagtgtattt
     2821 atagaattta tggaataatt tttaaggtgt tgacaaaata aatttataat ggtatataat
     2881 atatataatc tttttagcac tcgaacttag tgagtgctaa cagctaggag gtataataat
     2941 atggaattaa atgaaagaaa attaaatatc ctcaaagcta tagttaaaga ttatatagaa
     3001 acagctgaag ctataggttc tagaacaata tctaaaagac atgatttagg tgttagtgct
     3061 gctaccataa gaaatgaaat ggctgacctt gaagaattag ggtatttaat tcagcctcat
     3121 acttctgcgg gtagagttcc atctgaaaaa ggctataagt tatatgtaaa ctctcttatg
     3181 agtaaaagcg aattggatga taatgataag attcttattg aacaatgtat gaatcacaat
     3241 ataaatcata taaaagaatt gattcatgaa acttctaagc tattatcgca actaacaaac
     3301 tatacaactg tagcagttac taagagttta ataaatcaaa gtgttataaa gcacatacag
     3361 ttggttgcta tgaatgacaa taatatttta cttatagttg taacagataa aggggactta
     3421 aaaaaagcta accttacaac taatgtatat ttagatcaat ctaagttaaa tttgatttct
     3481 gataatctta caaggaagct cttaggtaaa agtataacag atttggatga taatctaatt
     3541 gcttttatta aatacgaaat aagtgagtat tctgggctta tagatgagct tttaaatgct
     3601 ttgaactcaa atatgaaaga agaagatttt tctctatcat taaatggagc tactaacata
     3661 tttagttatc cagaatttaa tgatgtatta aaagcaaagt catttttaaa tatgttggaa
     3721 aaaaaggaaa caatagctga cataattaaa tcaaagggaa tacaaaaaga caatctaaat
     3781 ataataattg gtagtgataa tgattgtgaa ctggcacagg attgtagtat agttacagca
     3841 acttataatg tagatagaga cttggttggg cgaataagct ttataggccc taccagaatg
     3901 gattatgcta gaatttactc tataataaat tatatgagtt tattaattaa tagaaagtaa
     3961 agaaatttta aattgcgagg tgtaaagtct tggataaaaa aaatgagcaa caggaagtaa
     4021 gagaagaaaa tgatacttct attaaccaag aatcggaaac tcaagtagag ttagaagagg
     4081 aagttgttaa tgaagaatgt gaaacatcaa gtgaaaaaac tgatgaaaaa gaagttgatg
     4141 atgaaaatgt aacagatata aattctaagt tagcagaaaa aaaattgcag gatgagttgg
     4201 atgaattaaa tgataaatat caaagacttc aagccgaata tgcaaactac agaagaagaa
     4261 ctcaacaaga gaaagagaca ataggcgtat ttgcaaatga aaaaataata actgaattga
     4321 taccagttat agatagtatg gaaagagcct tagatgcatg tgaagataag gaagatacta
     4381 tgtataaggg tataagcctt gtacataaac aattaataga cactttagta aaatttggag
     4441 tagaagaaat agaagcagaa tctaaggaat ttgaccctaa tctacatcta gcagttatgc
     4501 aagaaagtgt agatggagtt gaagcaaatc aaatagtaat ggtacttcaa aaaggatata
     4561 agctaggaac taaagttgta agaccttcaa tggttaaagt ttcttgctaa gtataaatta
     4621 aaggttaaat tatttaacct aatataaaat attaaaataa gtaaaactta attatataat
     4681 tactcgagga ggattttagt catgggaaaa ataataggaa tagatttagg aacaacaaat
     4741 tcatgtgttg cagtgttaga aggtggagaa gcacaaataa tagcaaatag tgaaggtatg
     4801 agaactactc catcagtagt agcatttaca aaagatggtg aaagaatagt tggagaacct
     4861 gcaaaaagac aagcagttac aaatgcagat aaaacaataa cttctataaa aactcatatg
     4921 ggaactgatt ataaagtaaa tatagatgga aaatcatata ctccacaaga aatatcagca
     4981 ataatattac aaaaattaaa atcagatgca gaaagttact taggacaaac agtaacagaa
     5041 gcagttataa cagtaccagc ttactttaca gatgctcaaa gacaagcaac taaagatgct
     5101 ggtagaatag cagggcttga tgttaagaga ataataaatg agccaacagc agcagctctt
     5161 gcttatggta tggataaatt agaccaagaa aagaaaatat tagtatttga cttaggtgga
     5221 ggaacttttg acgtatctat acttgaaata ggagatggaa cttttgaagt tttagctaca
     5281 gctggtaaca atagattagg tggagatgac tttgaccaaa tagtaataga ttatttagca
     5341 gaggaattta aaaaagctga aggtgtagat ttaagaaatg ataaaatggc tcttcaaaga
     5401 ttaaaagaag cagcagaaaa ggctaagaaa gaattatcat caacaatgag ttcaaacata
     5461 aacttacctt tcataactgc tacagcagaa ggaccaaaac acttaaatat agatttatca
     5521 agagctaaat ttgaagaatt aactagaggt ttagttgaaa aaactatgga accaactaag
     5581 acagctttac aagatgcagg actttctaca ggtgatatag atgatgtatt attagtaggt
     5641 ggttctacaa gaataccagc agtacaagaa gctgttaaga agtttatagg aaaagaacct
     5701 cataaaggta taaacccaga tgagtgtgtt gcagcaggtg cttctataca agctggagtt
     5761 ttagcagggg atgttaaaga cttattatta ctagatgtta ctccattatc tcttggtata
     5821 gaaactatgg gtaatgtaat gactaagata atagaaagaa atactacaat accaactaag
     5881 aagtctcaaa tattctcaac tgctgctgat aaccaaacag ctgttgatat acatgttctt
     5941 caaggtgaaa gaagtatggc ttatgacaat acaactttag gaagattcca attaacagat
     6001 ataccaccag cacaaagagg aatacctcaa atagaagtta cttttgatat agatgcaaat
     6061 ggtatagtta atgtttcagc taaagattta ggtacaggaa aagagcaaaa aataactata
     6121 acatcaaaca ctaatttatc agaagcagaa atagagcaaa agataaaaga agcagaaatg
     6181 aatgcagaag ctgacaaaca aaagaaagaa aaaatagaag cattcaatca agctgaatct
     6241 actatatatc aaactgaaaa aactttaaat gaacttggag ataaaataag ttcaggtgaa
     6301 aaagaggata tagaaaaagc tatagcagac ttaaaagctg taaaagataa tcaagatgct
     6361 acagcagaag aacttaagaa agctacagat gaagtaatga ctaagttcca aaaagtatct
     6421 caagaaatgt accaaaaagc agctcaagaa caacaagcgg cacaaggtgc agaacaagca
     6481 caagacaatg gacctaaaga tgacaatgta gtagatgctg actttaaaga agtagatgaa
     6541 gataaataag ctatataata tgtaacacta aatgataatt ggaacatata tgatttgtga
     6601 aaatcatata gatgttaaag atatatggac aatatacatc ataaagaata taatatatca
     6661 tagattatat aacttaaagt agaatataag aattaatgat agcttgtagt ttattattct
     6721 acaagctatc gttttgtaaa atgaaggtgg tgtcaatttt tgagtacaaa aagggattat
     6781 tatgaagtct taggtatcag taaaggtgca gaagctcaag agataaaaaa agcttataga
     6841 aaattagcaa tgaagtacca tccagataga aatcctggag ataaagaggc ggaagaaaaa
     6901 tttaaagaga taaatgaagc ttatgaagtt ctatctgatg atacaaagag aaaaacttat
     6961 gaccagtttg gacatgatgg gctaaatggt caaggcggtt ttggtggtca aggaggattt
     7021 ggcggtcaag gctttggtgg ttttgaagat atgttcggag atatatttgg tgacatgttt
     7081 ggaggaagct tcggaggtgg aagagcaaga agaagagggc ctcaacgtgg tgcagatata
     7141 agacagagtg ttactatatc ttttgaagaa gctgcatttg gtaaaaagat gtctataaaa
     7201 gtaaatagaa gtgaagaatg tgaagaatgt aatggaactg gagcaaaacc aggaacatca
     7261 aagaaaactt gttcaacttg taatggaact ggtcaagtta gaactgttca aagaactcca
     7321 tttggtaata tagcaagttc aagaccatgt agtgcttgta atggaactgg agaagtgatt
     7381 gaatctccat gtagtaaatg tcatggaact ggaaatacaa gaaaagttaa gactatagaa
     7441 gtagatatac ctgctggtat agatgatggt caaatgataa aactttctgg tcaaggtgaa
     7501 gtaggagaaa aaggtgctcc aagaggagac ttatatattg tagttaatgt taagtcacat
     7561 ccactattta ctagagatgg aaatgatatt tattttgaaa tgccaattac atttgttcaa
     7621 gcaactttag gtgatgagat agaagtacct actttggatg gaaaagttaa atatagtgtg
     7681 ccagagggga cacaaactgg aactgtattt agacttaaag agaaaggaat ccctagaatt
     7741 agaggtaatt caagaggaga ccaatatgtt aaggttgtag ttgaaattcc taaaaaatta
     7801 aacgataagc aaaaagaact attgagagaa tttgcgaagg agtgtgggtc gaacgtccac
     7861 gaaaagaaga aaaccttcgg acaaaagata gaagatatgt ttaagaaaaa gtagttaaag
     7921 tagccaatat ataatcatat ttttaaaatc ttagttattt ataagattgt caaaggagat
     7981 attatgattt ttatattggc tatttttgta taaaaaataa atgtgcataa aataaaactg
     8041 aatataaata attttctgaa aaatacttgt cctaaaatat ataatatgct ataatataat
     8101 caaataaaag aaaggggtga ttccagtggg aacggatgtg gcactgccaa atgatgaaga
     8161 aaactttatt gtaatataca aaataaaatt agatactttt agtgctagat taagtactgg
     8221 aaaaactcat gagctgggat aattattgta attacctaga ctcaaacttt tagtagtaaa
     8281 atagtaatat tatatagaca aggtatctaa tttttaaatc ttttgtatga attaaaattt
     8341 ttataaaggg tatatctgat tagaatgtaa ttagggaaac ctagttgtga attactttta
     8401 gtatatacat gtgtaaagaa atatgtatat ggtattgggt attgtgctag atgtgtatgt
     8461 aaaggaatat gtgtctagtt gggtatatgt aaagaaatat acttataatc tatgaaaaat
     8521 ttttagtata aattgctaaa acattgagat tgttttttat agaaagttag tttataccaa
     8581 ctaaaaatgt gcttaagatt tgtttgatgt ttaattataa ataaggttgt agataaaaaa
     8641 ataagtaaag acaaaggttt aaaatacttg ctttaaatat agtttgtttt gaacacttgc
     8701 caaattaaaa taattaataa aatagacatc ttctcatagt aaaatatact gtgagaggat
     8761 gtttttgctt tgttcataaa cttttatgaa aaatttgcat agtgtcacat tttaatatac
     8821 tatatatata ataaaatata gataaaatta aatgattcaa aagagaaagg tgaaaagaga
     8881 tgtattatat aggtgtagac ataggaggaa caggtataca agcaggagta gttgataact
     8941 atgggaagat aatttttagg tcagagtgta aaacagtaat tgaaaaagga tttgaaggaa
     9001 tacttaatga cataaaaata atgatttata agttgttgga agataataaa cttactatga
     9061 gtgacataaa atctattgga tttggtgttc caggttttat aaataaagaa ggattagtaa
     9121 cttgtgtaaa tttaaaatgg aataaaaaag cttttaataa agagttaaaa agaagatttc
     9181 cagatgttga aattcatgga gaaaatgatg caacagtagc agcacttgga gaagcaaagt
     9241 ttggaagtat gaaaggtgct aatgttggag tattatatac tttaggaact ggtgtaggtg
     9301 gaggaatagt aattaatcaa aaagtctttt ctggagcaca tggattgggt tcagaaatag
     9361 gtcatcaaat tataggagaa aactatttta attgtaattg tggaaataat ggttgtgtag
     9421 aaactttttg ttcagcaact gcaattataa agtattctca aaaactgata gaagaaggag
     9481 aaaagagtag gattttagat ttggcagagg gaaatttaga aaatgtaaat gcaaagatgg
     9541 tgtttgatgc atatagagaa aatgatttag tggcaattaa agtaataaat agatttaaag
     9601 agtatttagc aaaaactttt gcaaacacaa taaattcttt agacccagaa attatatcta
     9661 taggaggagg catttctaaa tctagcgata taatacttga tggaatagaa ggtttggtaa
     9721 gaaaatttgt attatacaaa acagaagata tagctacaat tacatgtgca actttaggtt
     9781 cagacgcagg aattatagga gcagcttttt tataatgtaa atgaactgct tattggaggc
     9841 gtgatgatat atgggtaaaa caaatgctag aagaacgctt tttttgatag caataggttc
     9901 aggaactatg ctgaatcctc ttaattcttc tatgatttca cttgctttac atagtataca
     9961 aaatgatttt catattagtt ttacaactgt atcttggatt gtttcagcat tttacctagc
    10021 tagtgctatt gcacaaccag tttcaggtaa gataggagat ttaataggta gaaaggtctt
    10081 atttttgagt ggtttgatgc ttgtaatttt atcagcatcc atagtaccac ttgttcaatc
    10141 attctttata ttgattttta taagagtaat tcaagcaatt ggaacaagta ccctatatcc
    10201 atctggagtt gctcttatac aaaataatat aaaagaaaga caatcttctg cattagcagt
    10261 tctaaccatt tttgcttcaa ctacagcagg attaggtccg acacttggag gattattgtt
    10321 ggacttagga ggatggcatg ctatatttct tgtaaatata cctgttgttt tggtttctat
    10381 atgcttaggg tattttttat tcccaaaaga agtaaaagaa aagaaatcta taaaagaaac
    10441 tttaaaaaat gttttgtcaa gattagatat tattggcata cttctatttt caattgcaat
    10501 gatttttata ttactatttt tgctatctat gaaggagtct tttaacttag aacaacttgt
    10561 atttggtata atactgatgt gtctttttat ttggcatgaa ttgagaacaa aattgccatt
    10621 tatagatatt aagctttttg taagtaatcc taaattgtca aaagtttact tgcaatttat
    10681 tatattaaat ttctttaatt atattttgtt ttttggtctt cctagttatt ttcaagatgc
    10741 cttacattat agtgcaaagt cgactggatt atttatgcta tttatgtctg gtataggtat
    10801 atttatatct ccattaactg gaaaatggat agataaatct ggaactagat ttcctcttgt
    10861 tacatcatca atctttatgt ttattagtgc agtacttctt tcagtagttt ttatccatat
    10921 acctgtaata ggaaagggta ttatattatc attagcaggt attagttatg gagttggtaa
    10981 tgtagccctg caatcctcta tgtttgaaga aagtcctcgt gacagtatag ggacagcttc
    11041 tggtttgttt caaactagtc gttatttagg ttctatttta gcaactgttt tacttggaat
    11101 ggtatttgaa gtaaatataa catcagaaca atttcagata ttaggttatg ttatggtggt
    11161 cttaggtaca ataagttttt tattaaattt tatattaaag aaagaattaa gaaaagtaga
    11221 atagtggatt tatggattta ataagtctaa taactgataa gtttaaaaat attgtttgta
    11281 aaacataact ggtttgatat ttattaattc taagttttga agcatagagt actcgataag
    11341 tatacaatat tttgaattaa aattaagcag aaatttgaac tagtctttca aatctctgct
    11401 taatttagta gttaaatttt tttatagaga aaataagatt tgacacttag ataaaaaatc
    11461 attgcatttt caaaattctt taaatcaaac ccaagtatct cattaatctt ttccaatcta
    11521 tatactagcg tgtttctatg taaaaacata ctagtagatg tcttagaaat atttaaatca
    11581 ttatttataa attttattcc tgtatataga agttcttcgt caatagattt aatcttatta
    11641 aaatctatta atttattgag tatattatcc tcattaatta aatctaaagt tttatatcta
    11701 ataaggtcaa acaaatttaa aaacttattt tcagcgttgt cttttataat atgaggtagt
    11761 aaatcagaac ataactgtaa tctaaaatca aaatcagctt tactatctaa ttcaccaaga
    11821 taaaaaatat aagtactttg ataagtttca gtttcaatta tattttgtgt agttacatta
    11881 atatctaagt tatatttaga atttactata aaaaaaccat tgtgttgtat tatatttata
    11941 tcttcaaata aattataaaa aatatttttt agatattcaa agtctatatg agattggtaa
    12001 attaaataaa agttgccttt taaattatca agattatttt tatctagaaa atcaataaca
    12061 taaatagcat tattgaaagt aactaaatgg ctactagcat ctaacttttg gttttcatat
    12121 ggatagatat ttattttttt attaagctgt ctttctaaaa aatcttttaa ctcttccata
    12181 aagtctcctt aaaaataaga ttatattctt atcttatagc taaagtagtt tctttgtcaa
    12241 atatgtgtac tctactattg tcaactgaaa gtgttaagtc atcaccaaca ttaattctgt
    12301 ttttactgtc aaatctaatt gttatcgtat tttctcctag ttttaagtga gcataagttt
    12361 ctgctcccat aagttctttt atttcaattc ttgatttaaa acaagtatct ggattagatt
    12421 taataaaagt atcttctaca tgaatatctt ctggtctgat acctataaca acttcattat
    12481 taatataatt gtcttttatt aaatcatagt gtttttcttt attcaattta agcttaatat
    12541 gttcattttg tgcataaatt tcatcatttt cttctattaa tattacatca ataaaattca
    12601 tctgtggtgc tccaataaat cctgcaacaa atatattagc tggataatcg tatacatctt
    12661 gtggagttgc aatctgctga actactccat ccttcattac tacgattcta tcagccatag
    12721 tcatagcttc aacttggtcg tgtgttacat agataaatgt agttccaagc tgttggtgta
    12781 gcttagttat ctctgttctc atagcagttc taagttttgc atctaagttg gatagaggtt
    12841 catccattaa gaatacctta ggatttctaa ctattgcacg tcctaaggca accctttgtc
    12901 tttgtcctcc agataatgtt ttaggttttt tatttaaaag aggtagtaag tctaatattt
    12961 tagcagcttc tttaactttt ttgtctattt catctttagg caattttcta agtttaagtg
    13021 caaatgccat attttcgtaa acagataagt ggggatataa agcatagttt tgaaaaacca
    13081 tagctatatc tctatctttt ggttctatat tattgacaag tttatctcca atgtatagtt
    13141 ctccttcaga gatttcttca agaccagcaa tcattctaag tgtagtcgat ttaccacaac
    13201 cagatggtcc tactaaaacg ataaattctt tatctttaat gtctatattt atatttttta
    13261 ctgcgttaaa tccatttgag taaagttttg atatattttt taaaattact tctgacataa
    13321 tatcctcctt gatatttaaa ttttaattat atagtatcaa atttttttat tatattaaat
    13381 gtgtaaaatg actaaatgta tttgtttaat atgtatattt agtttttagc aaagaataaa
    13441 actaacagta gaatatattt aaaaaattaa aaaacaaaat taaatttatt atcaaaaaat
    13501 cattttatga tatgttttat ttttatatta caaatagaga ataatgaatt atactagaaa
    13561 gtaggaggtg aaaatatgag cagaatttca atttttatgg aatcatgtaa tggcaaattt
    13621 ccaaatgaaa attcaatgtt gtcagtttcc tttataaaaa atattttaag tgcagaaaac
    13681 aaagattttg ctaaaaacat atttaactat ggggaagaaa gaaaaaacaa taagcaaata
    13741 aaggatataa atacagccat ttacatacca aatcttataa gaagcaaaaa tgagttactt
    13801 gttgatggag atataatatt caatataagt ttttataatt attctatgtt cagtaaatta
    13861 tacaatggaa ttttaaaagt aaaggagcta gaatataaag gttatagatt taaaataaaa
    13921 aatataaaaa tacataaaga acacgagata aaagaaaatg gtgttatatt taaaactatg
    13981 tctcctataa tagtaaagaa taaagaaggt aaatatttag atgtagaaga ttcaaattat
    14041 atagaatgtt taaactatat agctaatcta actctgggga gtataagagg tagtgggctt
    14101 agaaagccat tggaatttat acctattaac ttcaaaaaaa gagtgttaaa agaaaagatt
    14161 cgtggattta aagtgagaga atattactat ataaatgctt atgcaggaac atttttttta
    14221 aaaggagata tggaagattt aaatgcactg tataaaatgg gaattggata tagaaggaca
    14281 gaaaatgcag gaatggttga tatattaaag tagcgaggtg agagaaataa aagctaaatt
    14341 ttatagatca ggtgatattg taagagatat tggcattgtt tacttttatg aattactaat
    14401 ggatttaaaa aacgaactag aaaaaaatga ttataagcta aaatttactt gtgagttaaa
    14461 tagaaattat ttatctttag aatctgcaga atatatagac cctaagtata tatctgatta
    14521 tatattagaa aatcaacttt ttaaggtatt taaaaatggg aaaaaggaaa ccttagaaaa
    14581 aatatttagt aatatagata atttaatgta tgtaaatttt attgaagaat tggataaatc
    14641 ttctgcaact gctaaacaaa aggaagatat taaaaaagat tttaaaaaca ggaggtttcc
    14701 atatgttaga aatagtggta agtatggatt aaacacgagt ttaaaaaata tggaaacaaa
    14761 tgtaaaaaga atagtagata ctgtaattaa atcaaatata gagatagatg aaatagataa
    14821 acttgatttg acacaatatg aagaaaaaga tagtgtatgt aatgtttgta atataaataa
    14881 aacaacaaaa ctagatattg atttaagaga gcgaaaggac tctaagtata actttttatt
    14941 tagaggtgca gaaaaatcag gctttaaaag aagtggacaa gttgaaagta atatttgttt
    15001 tgagtgtgaa tttttcaact taatgtgtct tttatatata aatttaaaaa gaccaatggt
    15061 ttttgcatat acgaatgatt taagggaatt agcattttta aatcataaga taatgcttaa
    15121 aagaaagatg tattcagata aatcatttta taaaaaactt ttgcatgaaa aaataagttc
    15181 aattagacta tataggtttg atattgatac gaataaaggt ataattctaa agtttgattc
    15241 tattatagag tataaagaat tattaaaaaa aattgaactt atagatatta tagataatta
    15301 taatttttca agagagccag gtaatactag aaatttgggt aaaagaatga ttgataatgg
    15361 gaatttatca aatttaaaag aattattact tgataatata agtgttttaa agcaatcaac
    15421 tggaacttct cgagaaatgg attttgtatc tagctcatat aatatcggtt tatatataaa
    15481 attgtgttgg attgtagatg gaggggagga gtataaaatg aaaaactata tggaaagtaa
    15541 tttaatatat tcaagagtag gtaaagactt atttaataaa atgacagatg aatccagaag
    15601 aaaaaatttt tctatgaaag tgattcaact acttaagtct aatgatagaa ctcagctatt
    15661 tcaaactata atgcatgtgt tagtttctaa tggaatctta ataggagaag ggtttgtaga
    15721 aggtctaatg cagagttctg aattagaatt aaatacgaat gtaggtctat ttattcaaga
    15781 aatcatgaaa taaaaaaggg ggaaaattta aaatgaatga aaaaagagta aaaggagtaa
    15841 cattaactat actgacagaa agcccagttc cactttcata tgaccaaggg tatggaaatt
    15901 atacaccaat aaaaaaagaa caatatagag aaaaaataca tgcaaaaact agtatagcca
    15961 caataacata tgatttaaga agaatgctcc accaagaata tggttggaat ttaagtaata
    16021 ttgtttttgg aaaaaaagga aatatatatc catctattaa gaaaaatgta ggatgtgtag
    16081 atgaaaatgg attagagact gatgtatttg gttatttaat accacttaaa gataaaggtt
    16141 ctataagtaa agcttctcca cttagaataa taccttttag gtcattaaat ccatataaag
    16201 gttcaacaca gctaataaca aatagaggct ttttaagtag tgaatttggt agaaaatatt
    16261 atgatgagaa ggaagaaaat gaagtaccta gagatgaaaa ctttccaaca tcacaagcat
    16321 tagcaataga agagacttta tcagattact acgtttatac aataacattg gagcttgata
    16381 gaataggagt agtagaagta gaagatggaa agttactttt accagaagaa agaaaattta
    16441 tgagtaagga gttaagagaa aaagcagtaa aagatatatt agatgcaatt actgtgttta
    16501 caagaaacat aaaacattca tcagtactat taaaaccact tgcagtaata ggtggagctt
    16561 ttgataaagt tgtaccattt ttttgggatg atgtagatta taatgctgat agtggtgaga
    16621 taaatttaga gggagtcata gaaactatag aaagttatag ccttaaagaa agtaacacaa
    16681 tacttgctat caatgataga ttaaaaattt ctaataaaaa ggaattaaat aagtttaatt
    16741 taagtaaata ccctgtaaaa gagattaaaa atctagcaga tagattggaa attggagaag
    16801 ataatatgtg gtatttaaaa gagtaggagg ttttttgaat tatgaaagta ttacaatgta
    16861 aacttaagca accaactgct cactatagag acccaaaagt atttcaaaat gaatatataa
    16921 gtactttaaa tttaccatct aagaccacaa taatgggaat gataacgtat ttatgtgata
    16981 gaagattaaa ctctgatata gatataggaa taattggaac acatcatcat agagaactag
    17041 aattttcaag aggagaaaac attgattttt ggaatgaata tataaaaatg ggaaaaggta
    17101 aagataaaga aaagtttttg cttaaaggaa actactatga ttactataaa gagcataaag
    17161 ctcaaaatag catattaaac tatgaagttc ttaaagaagt agaactgact atatttattt
    17221 cttgcaagga tgatgaagaa cttgaattta ttagaaaaaa gcttgaaagt ccatgtaaat
    17281 atgcaaattt aggaagaaaa gaagattttg taataccaag tgaaaaaggg tgttttgtga
    17341 aagaagttaa gttaaaagag gttataccta tgaatactcg tgatgctata aaagaaaata
    17401 taaaattaaa gaatacatat gtaagagttg acttaagaga taaagagaat gtcgagacta
    17461 taataaatca aggtgtattg attgcattgc ctcataaata taaagattta gaagcaaata
    17521 gagatgatag agtttatgag ttttgccatt atatatatgt tgataatgat ggtatatatc
    17581 ctaaaaatat taaggtaaat gtatgtattg atacaaaaga agtttttaca tggctttaaa
    17641 ttattttgaa agataggtgt ttatcatgaa aaatatcatg caaaaagaaa tattagctaa
    17701 gtcatacaat ttaagaacta atcaacaaga gcaaacatta gttgaacata ttaaggattt
    17761 atttgaagta ttagaatcta tattagaact aaatctatat tcagataaag atgtagagat
    17821 actaaaaata tgttgtgctt tgcacgattt aggaaaaatt aattcaatta tgcaacaaaa
    17881 aatggagatt aataataaaa tatcgtatag ttgttcagaa gaagagagga aaaagttaga
    17941 gtctgacaaa aaatctttaa aaaagatagc aagacacaat atattttctg gagcattttt
    18001 aaaaaatata ctagaaaaaa tgaacttgtc agaagaagat aagttatata tatataaaag
    18061 tataatgtta catcatggaa actatgaaga ttatatgagg ttaagtacta gtaaagttca
    18121 aaaagaaatt tatgattata ttgaaaaagg tattttagaa aaagaagatt ttaatttgga
    18181 agatatagaa gattatataa aggagatttt atatgtagat tttaaattta atgaagatgt
    18241 attggattat gattacatag ataaattaag tgaaagtatg gttatagaca gtgattataa
    18301 caatggtcaa atagaagatt cagttttaaa ttatagaaag tttaagtata ttttatataa
    18361 agggatgctg aacttaatag accatagtgc atcaagtaga cagaaaggta taaaatttta
    18421 taacgatttt actgatgaag aaattgataa tatgatttta aatgagatat ataagagtca
    18481 gggtaattta gaaaaaaata atatagagtt caatactata caaaaaaggt tgagagaact
    18541 ttctggaaga aatgttctga ctgttgcatt tacaggttca ggaaaaacag ctgcagatta
    18601 tagaaagact tttaaaagaa aattcttttt agtgccaaat aaaatatcag cagaaagttt
    18661 ttatagaaaa aatatttttc aaaataaaaa tgatttagat acaagaagta gtaatgatta
    18721 cattggatta cttcatggag atataaactt atattcagag aatgaagata atggagaaaa
    18781 tgattttgta ttgacattaa gggatataga tttgagtata aacttttgca aaccttgtgt
    18841 aattgcaaca gttgaccagt tattacttag tatgtttaaa tttccgggat atgaaaaaat
    18901 attcgcagcc gtaaaaaatg catctataac tgttgatgaa gtacatttat tggaaccaaa
    18961 gatgtttttg attttgatat attttatgca gtttgcatgc aagtacttag atgttgattt
    19021 tcacttaatg acagctacac ttccaaaatc atataaagag caaatgataa acaagggaat
    19081 tatttttcaa gaagaaagta atgaaaatgt tactgataaa ggagaaatag tttttattga
    19141 gagcaacaag gaagaagaga tttgtgaagg taaagatgta aaggtttctt ttataaagga
    19201 aaaagaaatc aagtcaatag ttgaagatgc tttagaaaat aaacaaaaaa ttcttataat
    19261 aaagaatact attgattcag tcaatagaac atatgagttt ttaaaagaaa atttatctga
    19321 taagtatggt ggtgtagata tagatgtttt acatagtaga tttaagttca aagataaaaa
    19381 agagaaatat agtaaaatat taaatggaga gggtgatatt tggatatcaa ctcaatcagt
    19441 agaaatatcc ttggatttgg atttcaatat aataataagt gatttagcaa ctatggatag
    19501 cttaatacaa agaatgggta gatgcaatag aaataataaa tatgaatatg gaaactttta
    19561 tattctacct agtgaagata aaatttatga taacaaactt aagaacacaa ctaaaagcat
    19621 cttaaaggac atattaaaaa ctaactctat ttttacaatg gggattagaa aaactatttt
    19681 ggatgattac tatgataata gtgtagttaa aaaatatttt gaagagaatt ttataagttg
    19741 tgataaagaa attaagaata tttatggtat aaataaagaa atttttgatg gattggattt
    19801 aatttttaat tttgaacctt acaaaaatat tgttgatagt aagaaggaag cagctaaaat
    19861 ttttagagat gttgatgtta gttacaaaat tattctggaa gaagattttt ataaggaaga
    19921 tagggagtta caacaagatt cgattcaagt atcagggttt atatttaata gattatatta
    19981 ttatggatta ataagcaaag tagaaggata catggtacta aaatctagta gtaagtttga
    20041 gtataatagt actgtaggct taattttgaa gtgagcatat gtttaaatat aatatacctt
    20101 tagacattga aaatacaaaa agtactactg taagtctact gtaaaaacta ttttttaaaa
    20161 ggaaaaataa gttgtgagat agagtgttta caagtgtata tagataataa atttgaggtt
    20221 taagattaac taagtgggtt tcaggtacat cgcgaaaata attataagtt ggagattttg
    20281 tatgtttaag attaactaag tggatttcaa atattgatat agtagatata atagaagttt
    20341 tattattagg tttaaaatta actaatcgga tttttaaata ttctgactat tatataagga
    20401 tattattaga ttgaatttaa aaccaataat ataaaacaac aaaatattat atttatgata
    20461 taataaaagt tatggaaaaa caggaatatt actatagaga agagaggtaa acttatgaat
    20521 aattggatag aagtaactat aaaaacaaca acagaagcag ttgaacctat aacgaatata
    20581 ctatatgaac aaggagctgg aggagctgta atagaagacc caaaagactt tttattccaa
    20641 aagaaaaatg aactagattg ggattatgtt gaagaagaag tatttaaaaa gaatgaagaa
    20701 gatgatgttc ttataaaaac ttatgtttct gaagaaaaaa atgtgatgga atttgtcgaa
    20761 ataataaagc aaaaagtttt aggattaaaa gattttggta tagatatagg tgaaggaagt
    20821 gtatcattgg accaagtaaa tgaagctgat tgggcaaatg catggaaagc atactacaaa
    20881 ccaacaaaag tgggacaaag ggtagtagta aaacctacat gggaagatta tgctatgcaa
    20941 gagggggatt taatcataga gcttgaccct ggaatggcat ttggtacagg gacacatgag
    21001 actactagta tgtgcattag agaattagaa aagtatgtga ataaagattc taaagtattt
    21061 gatattggat gtggtagtgg aatccttgca atagcagcag ccaaattagg agcaaaagaa
    21121 gttgtagctg tagatttaga tgaagtggct gtaaaagttg caaaagaaaa tgttcttgaa
    21181 aataaagttg aaaaaagtgt atctgtaatg catggtaatt taaccgatgt aataaaagat
    21241 aaagcggatg taatagttgc aaatataata gctgatataa taaagatact tgcaaaagat
    21301 gttcaaaact ttatgaaaga agatgctata ttcatatctt caggtataat tttggataaa
    21361 gtagaagaag ttaaagaaag cttaattgaa aatggatttg aaatagttga agttcaaaaa
    21421 ttaggtgaat ggtcagcaat agtttctaag cttaaaaaat aagggatatg gtgacgtata
    21481 atggatagat tttttgttga aaaaaataat ataaatctac aagataaaac ttgcactata
    21541 gaaggtgaag atgtaaaaca tatttcaaaa gttttaagat gcaaattagg tgagaaactt
    21601 gaaatatgtg acaagaataa taatgagtat atttgtgaga taatgaatat agataagagt
    21661 atagttaatt tagagatttt agaaaaagtt gatataaata gagaatcaga acttaaagta
    21721 aggctatacc agggacttcc aaaagctcca aaaatggaaa tgatacttca aaaattaact
    21781 gaagtgggtg tagaagaaat aatattagtt caaactaaga gaagtgttgt taaagttgat
    21841 gacaaaaaag aagataaaaa atttgaacgt tgggaaagaa taatttatga agcagcaaag
    21901 caaagcaaaa gaggtaagat accaaaatta agaggtgttt taagttttaa agaagcttta
    21961 gaagatatga aaaaaaataa tgtaaatatt tgcccttatg aaaatgaaag aacagtttca
    22021 ataaaacatg cactaaaaaa atgtgattct aatatagata gtgttggaat ttttataggt
    22081 ccagaaggtg gattttctga agaagaaata gaacaaatac aaaaaaataa ttgtaatgtt
    22141 gtatcattgg ggcctagaat attaagaact gagacagctt ctgttgtagc atcaacaata
    22201 gctttgtatg aactaagtga tttaggagga gaaaaataaa ttgaaaaaag tagcttttta
    22261 tacacttggg tgtaaagtta atcaatatga aacagaagct atgctagaac tatttgagaa
    22321 agatggttat gaacaagtca atagtgaaga gtatgctgat gtttatgtta taaatacatg
    22381 tacagttact catatgagtg atagaaaatc tcgtcaatat ataagacgag ttaaaaagaa
    22441 gaatccagat gcaataatag ccgttgtagg atgttattct caggtatctc cggaagaaat
    22501 tttggatata gaagaagtaa atttagtcat gggtacaaat gatagaagaa agattgttga
    22561 agaaattaaa aagataaatt caagtaagaa agttagtaca gttgacgaca taatgaaagt
    22621 taaagctttt gaagaaatag aaatcagcca aactaatgga aagactagag catttatgaa
    22681 aatacaagat ggatgtgaca gattttgtac ttattgtatc attccttatg cccgaggacg
    22741 cgttagaagt agagatattg atagtatagt cgatgaagtg aaaaaattgg ctaataatgg
    22801 ctataaagag gttgtattaa caggaataca tgttgcctct tatggaaaag atttaaagga
    22861 tagggatatt aaacttcttg atgtaataaa acaaataaac cagatagaaa aaatagaaag
    22921 aattaggctt agttctgttg aaccaatttt atttacagat gaatttgtaa atgaagtttt
    22981 aaagatggat aaagtttgtc ctcattacca tttatcactt caaagtggat gtgatgaaac
    23041 tctaaaaaga atgaatagac gatacacaac tttagagtac aaaactattg tagatagatt
    23101 gagaagtaaa atgccagatg tggcaataac tacagatgta atagtaggtt ttcctggaga
    23161 gacaaatgaa gagtttaaaa aaacgtacga gtttttaaaa gaaatagagc tttcacaaat
    23221 gcatattttt aaatattcac caagaaaagg aactccagct gcaactatgg aaaatcaagt
    23281 tgaccctcaa atgaaacact ttagaagtga acaactttta aatttaagta aagtaaattt
    23341 taataaattt gcaactaaat ttatcggccg tgagttggat gttttgtttg aacaaaatat
    23401 agaaggcaat aaatatgagg gattaacttc aaattatata agagttgttg ttgaaagtga
    23461 caaaaatata caaggtcaga tattaaaagt gaaaataaat gatgtaaaag atgaatatgt
    23521 agaaggaatt ttgctataac atgtagaaat tataatattt ataagatagg aggtggaaag
    23581 aatggattgt attttttgta aaatagcgaa cggagaaata ccttcaacta aagtttatga
    23641 agatgataga gtcttagctt ttaatgactt gaacccagtt gctccatatc atatattagt
    23701 tgtacctaaa aaacattatg atagtttaat tgatattcct gataaagaga tggacattgt
    23761 gtcacatatt catgttgtta ttaataaaat agctaaagag aaaggttttg accaaactgg
    23821 attcagagtc ataaataatt gtggaagtga tggagggcaa gaagttaaac atttgcacta
    23881 tcatatttta gctggtaaaa agcttcctaa ttacgaagcg ggacaaaact aaactaaatt
    23941 attgaaaaat tgagttcctt cttgataaaa atacttgata aaagtaaaaa tttagtttat
    24001 aataaacaaa gtgttaggtt gtaatgcata ttatgcaaaa agaacatagt tacagtccca
    24061 gcataattgc gctattggag ggagggaaaa agaaatgtca gaagtaagag ttagagagaa
    24121 tgaaacatta gacagcgctt taagaagatt caagcgtcaa tgtgcaatgt ctggcatcat
    24181 gtcagaagtg agaaaaagag agcactatga taagccaagc gttaagcgta agaaaaaagc
    24241 tgaagcagca agaagaaaaa acgctaagaa atagtagtaa ataagaataa agaggtgaag
    24301 gggatgtccc ttaagcaaaa gttacaagag gatttgaaat cttcgatgaa aaacaaagat
    24361 acagtgagaa aatctgtagt aactttaata agagcttcta taaagcagta tgaggttgat
    24421 aatagggtcg agcttgatga agatggaatt atcgatgtaa tagcaaaaca attaaagcaa
    24481 cgtagagatg cattagttga atttgaaaaa gctggaagag aagacttaat aaaagaaaca
    24541 gaaggtgaaa ttgaagtttt aaaagagtac ctacctcaac aattaagcga agaagagtta
    24601 gaagaaattg taaaatctac tatatctgaa gtaggggcaa cttctatgaa ggatatggga
    24661 aaaataatgt cagttatcca accaaaagtt aaaggaagag ctgacggaaa acttataaat
    24721 aagttggtaa aacaaaactt acaatagatt gatatagcct agagagaaat ctctaggctt
    24781 tttatagttt ttgggaataa cgagtcatat ttgagcatat ctataatcaa agaaaatttt
    24841 gaaagaaggg gaaaaatttg attatatcag taaaagagat taggaatttt ttgataaaca
    24901 tatttatacc actaataata ggttacttaa gtagcatctt aacaatgatt atcagtggaa
    24961 cagatatttc aacctattat ttacaactca caaagccaag ctttgcacca ccagctttta
    25021 tctttcctat agtttggact atattgtaca tattgatggg tatatcttca tacctaatat
    25081 taagaaaagg ttacaactta cctaaagtaa gagatgcaat tttttattat ggattacaac
    25141 ttgtattaaa ctttatttgg agtatactat tttttggatt tggacttaga tttacagctt
    25201 tgatagatat aataataatg attttggttt ctataataat gatttcgaag ttttctaaaa
    25261 tagataagag atctggatac ataaatttga tttatttaat gtggcttgtt tatgcaggat
    25321 ttttgaacta ttttatatgg tttattaata aatagaatgt aaagattttg taaattaccc
    25381 tgtactttta ataatatcat aacaaacgaa aaataaatag actattaaaa ataatcattt
    25441 tcatatacaa taatattaat ttaaatacaa taaatttata aaaattgtat ttaaagatta
    25501 acatattaaa gtattagaat tggaaaggct tgaagggaga ggtttttatg caaataatag
    25561 tatctgggag acaaatgaaa ttaactgacg gaataaaagg atacgtagat ggaaaattaa
    25621 gtaggttaga aaaatacctt gatcctgaat cagaagtgaa agtaacagta agtgcgaaaa
    25681 aggatagaca aaaagtggag gttacaataa ttcctattaa cggtcaaata ataagagcag
    25741 aagatgtaga agatgactta tatgcagcaa ttgatattgt ttgtgacaaa ttaagtagac
    25801 aagttgtcaa atataaaact aaagttaaag acaaagttca aaataataag agcataagat
    25861 ttgaaaatct tgactttata gataatagca gtgaatttga tgattatgat tatgatgatg
    25921 aagaagatga aaatatagta atagaaagaa gaaagaaatt taatgtaaaa cctatgagtt
    25981 ctgaggaggc gatacttcaa atggaactag taggacacaa tttctatatg tttagaaacc
    26041 aagataattt tgaaataaac atagtgtata agcgtaaagc tggtggatat ggtttaatag
    26101 aacaagatta ataaaaattg tatacgttta gattttatat aagaaaaaat aaaaaggtaa
    26161 tcatgttgat tttttatcaa tatgattacc tttttcttgt ttaaataata tattagatat
    26221 taggtattta ttatataaaa attttaaaac taatctgtta caacatcaat aaagtgcata
    26281 aatacctatt tcaagcataa aattaattaa gggggtaatg cttatgttag aaatatccac
    26341 tgatttacaa gtaaatcaac cagttattac tgttacaagt aatacgttta ttagtataga
    26401 aaattatcta tcaatattag aatatgaagt tgatttaata agaataaaga ctaaagttaa
    26461 aacaattaaa atatctgggg ataaactttc acttaagtat attactgata gtgagatagg
    26521 tataaaaggg attatctaca atgttgagta tgttgattag gaggagatac acttgataag
    26581 ttttataagg ggatactatg ttatagttgt ggaaggagta ggactcgaac aatttttaaa
    26641 tcatcttata agaaatggga taagtgttta caatgtaact agaataaaaa atactaaaat
    26701 ggagtttcat atagatagac aagatataaa agactttaag aatgtttata gaggaagtaa
    26761 gtttgatata aaggtaaagc aaaaaactgg ggtccctttt attatcaaaa gagtttataa
    26821 gcacaaaggt atgtggattt gtgctcttgt ttctttattt ttattgatgt ctacatcaca
    26881 gtttgtgaca gatgtatata tacaatctcc tgaaggtata aaaaaagaag ctcttagaaa
    26941 tgagctttat aaggttggag taagaccagg agtctataag aagagtattg atagaaaaga
    27001 agttagagac catatgatgt caaaatttaa tgatgtggca tatttatcta tcaatgtaaa
    27061 aggaacaaat atatttgtta ctgttacaaa aaaggcagaa tccctaaaat ctacagacca
    27121 atcaaattat tgtaatgtaa ttgctttaaa aaatggtata atagaaaagg taatccctag
    27181 aagtggtaaa tcagttatta aatctggaga catagtccaa aagggagatg tcttattaaa
    27241 tggagctaat accaagtcaa taccagaagt atgggcaagt actttttatg agtccacaaa
    27301 aaaggcaagt tatgtagata ctgtaaataa aaaaactgga gaaaagaaaa atatatatac
    27361 actaagtttt tatgataaag agtttacaat gagaaaaaat ataaaatata aagattatgt
    27421 tgttgaaaat aaagaaaaaa aactatcaat aggaaactat acttttccaa taaagataaa
    27481 aacgagtact ttttatgaaa caaaaaaggt tgaagtaaaa aggaataaag aagagttaaa
    27541 aaaagaatta tctgaaaaag ctttaaaaga gttagaatac ataatcccag cttcggctag
    27601 aataatagat gtaaaacata actttaaggt taataaaaat atgttagaat atttaataac
    27661 agttcaaact agtgaaaata ttgctaaaat ttatcctctt agtaagtcag aagcagaaag
    27721 gtttataaag gaagaaagta aaccagatga aggtgaagag gaagttcctt ccaatccaga
    27781 aaaaagacca ttaaatgata taagaaatga gtttgatgag gataataagg ataataaaga
    27841 tcaaaacaat tctgatgaaa ataatagtaa tcaaaatagt aataatagtc aaaataataa
    27901 tagcaataac aactaataaa attaaactta aaatcttagg aggactaatt caattgataa
    27961 tacaaaagaa atttacaata gcagatggta actttgaaag agagttattt ggcaactttg
    28021 atgaaaatgt aaaattaata gagaagactt taaatataga tgtaatactt agagaaggca
    28081 atataatttt aattggagaa gaaaaaaatg tagattctgc attaaaactt atgaatgaat
    28141 tacaccaaac tgtatcaaat ggtaagcatt tagataagca gagtatttct tattcattat
    28201 ctcttttgct tgaaggaagt gaacaaaaaa taaaagaact tgaggggaca atcgtcataa
    28261 ctcaaagggg aaaagctgtt caacctaaaa ccttaggtca aaaagaatat ataaaactta
    28321 tagaaaataa tgatataact tttggtgttg gacctgctgg aacaggaaag acctatcttg
    28381 cggttgctat ggcagtaaaa gcttttaaaa gagatgaagt tagtagaatt atacttacaa
    28441 gaccggctgt ggaagcagga gagagtctag gttttttacc aggagattta aaggacaaag
    28501 ttgacccata tttaagacca ctatatgatg ccttatttga aatgttgggt gctgataaat
    28561 ttaataagta tttagaaaga ggaactattg aggttgcacc acttgcattt atgagaggta
    28621 gaacacttga taattcattt ataatattgg atgaagctca aaatactact tctgaacaaa
    28681 tgaaaatgtt tttaactaga cttggatttg gctctaaagc tgtagttaca ggagatgtaa
    28741 ctcaaacaga tttaccacaa aataagaaga gtggtctaat acaagctaca gagattctta
    28801 aaggtgttcc aggtattggg tctataatgc taacagatag agatgttgta agacatgagt
    28861 tggtacagag aataataaga gcttatgaga agcacgacaa aagagaagaa tttaaaaaag
    28921 aagaacgtaa aaaagcgaaa atgcaggaaa agactttcaa aagaaagtaa aagtgtagta
    28981 atatagatat atagcattat taatgaataa aaagtaggtg tagtgaatgg atttgatact
    29041 agatgataga caagataaat tagaagtaag tgaggagtta attgaaaaga taaaggatat
    29101 aatcatagaa tgtttagatt atgaaggata tgatgataat tatgaagtga gtctttcttt
    29161 tgtagataat aaagagattc atgaattaaa tagagaatat agaggagttg atagagtgac
    29221 tgatgtttta tcatttcctc ttttaagtga tgattttgag gatgttgaat tagaagaaga
    29281 atccctaggt gacatagtag tatctcttga aagagcctta gaacagagta tagagtataa
    29341 ccatagcttt gaaagagaag tatgtttttt aatatgtcat agtatgtttc atcttttagg
    29401 ttatgaccac gatacagatg aaaatacaaa agaaatgaga gaaaaagaag aacacatatt
    29461 aaataagtta aacataacaa gggagtagtt tttatgaaac cagaaaaaac tcgtcaaggt
    29521 ataattaaag catttaatgc agctatagaa gggatattgt atacatttaa atttgaaaga
    29581 aatatgaaaa tacattattt aggttcagtt gctgttctta taataagttt gttttttaac
    29641 ttttcaaaat tagaaatgat aatgttactt atgtccatat gcttagttgt agttgctgaa
    29701 atgtttaata cagctataga aaaagctgtt gatttagtaa ctgatgaata tcatgttctt
    29761 gctaagatag caaaagatgt tgcagctgga ggcgttctag tggcagcact aaattcagta
    29821 gtagttggat atattttgtt ttatgataaa ttgacagata tatctggaat attaatttat
    29881 aaaataagag aatcagaatt acatataacc ttgatatgta tattattggt tcttatagct
    29941 gttgtagttg taaaagcatt gacttctaca ggtactcctc taaaaggagg aatgccaagt
    30001 ggtcatgctg ccttagcatt tgctatagca actgcaatta cacttatgac tgaaagagtt
    30061 gttgcctcta ctcttgcata tataatggct gtattagttg cccaaagtag aattgaagga
    30121 aaaatacata ccttttggga gactattgct ggagctttgt taggtgtgtt gatagctata
    30181 ttagtatttc agcttggaat gttctataat taaaataaat gtacataaaa tatttaaaat
    30241 aaaacaaatc tgtgctaatt aaatttttat gatataatgt agagtattaa ataaaaataa
    30301 cttttaatta ttgtatacag gaggagttgt tgtggataac atagaattgt taaggttggc
    30361 agaagatgcc agacaacatt cttatgctcc ttactcaggt tttagagtag gtgcagctct
    30421 tttaactaag agtggtaaag tttatactgg atgtaatata gaatgtgcat cattaggtgg
    30481 aacaaattgt gcagaaagaa cagctatttt taaagcaata tcagagggtg ataaggatat
    30541 ctataaaata gctatagcaa gtgataactc agaaaataat gagcaaacat atccatgtgg
    30601 aatatgcagg caggtaatta tagagtttgg ttctgatata aaaataataa cgggatatac
    30661 taaaggagag gtgtttgagc atagtataaa ggatttgttg ccaaactatt tctctggaaa
    30721 tgatttaaaa taaatttaaa agtataaata aatttaagta attaaaacaa gaagataaaa
    30781 agttaggaga cagttaatgt tcaaatcagg ttttgtcagt atagtgggta gaccaaatgt
    30841 aggaaaatct actttaatga ataatgtagt tggagaaaaa atagctataa tgagtgataa
    30901 gcctcaaact acaagaaata caatacaagc agtatataca gatgaagaaa tgcagatagt
    30961 attcttagat acaccaggta ttcacaaacc aaaaaataaa ttaggtgaat ttatggtaaa
    31021 ggcagcaaca gaagctttta aaaatgtaga tttaatatta tttgtagttg atgattctaa
    31081 aaaaataggt cctggagata gaaagataat agaggattta agaagtgtta agacaccaat
    31141 aattttagtt gtaaacaaaa tagaccaact agaccaaaaa gatgagctat ttgatataat
    31201 caaaatgtat gatagagaag gcatttttaa agaaatagta ccaatatcag cattaaaagg
    31261 aaagaatacg gataccttaa taaaagttat acaaaattat ttagaagaag ggccaaagta
    31321 ttttccagat tatatgatta cagaccagcc agaaagagta ttaatagcag aacttataag
    31381 agaaaaagtt cttcactatc ttaatgatga aatacctcat ggtgtagctg ttgaaattga
    31441 aaaaatgaaa gcgagaaatg ataaggaaat agtagatgta tctgctgtaa tatactgtga
    31501 aagagattca cataagggaa taataatagg aaaaaatggt aggaaactaa aaggaatagg
    31561 taagtcagca agacaagata tagaattgct tttaggttca caaataaatc ttcaattatg
    31621 ggttaaagtc aaagaaaatt ggagaaattt acaaaattat ataaataatt ttggatataa
    31681 tgataaataa aggtgggtta tatggatagg aaactggatg cttcccaaga tttattatat
    31741 gaagtaaaat cattaattga taataataaa gtattggagt taagagaatt aatagaggaa
    31801 tatcatataa ttgatatatt cgatataatg gaaaatttag aggaagacat gaaaattcaa
    31861 ttatttgaag tacttccttt agatatggca tcttctatat tagaagaagg tagtgtagag
    31921 ttttttatta gtattttatc taaactggat gtagaacact cgaaaaatat acttgaactt
    31981 atgtctcttg gagatatggc agacaagttg agtgaacttg aagaagaaga aagagaacac
    32041 ataataaatc ttttgaatca agagaatgcc gattatgtaa aagagttact attctatgat
    32101 gaagattctg ctggtggaac aatgaccact ggatatattt ctataaataa agatatgaca
    32161 gctcttgagg ctatagacca tatgagagaa gaagctgaag aagctgaaac tatttattat
    32221 atatatgtgg ttgatgatga agaaaaacta gttggagtat tgtcattaag agaattaata
    32281 atagctagag acgcaaatat agtagaagat ttgatgagtg aaaatataat ctctgtttat
    32341 gtagatgaag atagagaaga agcagtaaga ttagtatcta aatacaattt aatagcaatt
    32401 ccagtagtag acagacaaga aaaattaaaa ggaataataa cagtagatga tataattgat
    32461 gtaatggaag aagaagcaac tgaagatatg tataaatttg caggaagttc agaacatgaa
    32521 agagaagttg ctgaaaaaga aaaccctaca ttgagagagc aaataatatc agcacttaga
    32581 ggacgattac cttggttaat tattacctta gttggagggt tgttggcttc gttaatactt
    32641 tctaacttag actatataat gaatcctgta tatgctccat tagtattttt tatacctgta
    32701 gtaattggta tgggtggaaa tattggaact caatcatcat ctgttacagt aataacattg
    32761 tctaataagg atttaaattt tagcaatgtg gttagagaag gtattgtagg tattattaca
    32821 ggtcttttgt gtagtataat aacaggtatt gtaatttact ttgttatgag aaagttagac
    32881 attgtattaa ttgtttcaat atcattattt ataaatatgg ttttaggtgc aacaataggt
    32941 gcgtttatgc ctgttttatt aaaaaaaatg gatgcagacc catctacagt ttcatcacca
    33001 attatatcta cagctcttga tataactggt atagcagttt actttataat aacaacggca
    33061 ttattgtcaa aaattgttta ataactttat gtatgattta tcctcttctt actaaaaata
    33121 taagtataaa tgtaagaagg gggtttttta aaaatgaaca atatcagttg ggaagttttt
    33181 aaaaaaacag gtagtataga tgcatattta tatttctgtg attgcaaaaa catacatgaa
    33241 gaaattgaag aagtaaggga gaaaaaagaa gacgatgata atcctgaaca cccaggggat
    33301 agtacttaaa gctataaggt ataaggaaag tgatataata cttacactat ttacaagaaa
    33361 gcttggaaaa gtatctgcaa tagcaaaagg agctaaaaaa aataagagct ctttgctttc
    33421 atcatcacag ttattttctt atagcaattt taccttaaaa aaacaaggta atatgtacaa
    33481 ggttactcaa agtgaaataa taaaaagttt ttataatata tcctatgata tagaggcatt
    33541 ttcttatgct acatatatta caaaattagt tgaaaattct atacttgaaa atcagactaa
    33601 taataggcta tttatattac ttgcgcagac tctgtatttg tatacacagg ataatacaga
    33661 caataggttt ataacagcag cattcgagtt aaaattttta gactatatag gatttaaacc
    33721 tatagtaaat aaatgcatta attgtgaatg taaaatttta caaaattctg tgtttaatat
    33781 ctacgaaggt ggtatactat gtagtaagtg tagtaaactt tttgataata atataaaatt
    33841 agacttaaca actataagtc ttatggaata tgtattaaga aatgatattt taacatgtag
    33901 taaagctaaa gtatcaaaat atataacaca tgaacttgag aatattctag acaagtattt
    33961 gaaagtttat gttgataata ttaattttaa atcattacac gtattgcaaa gtgtaaaaaa
    34021 taataaggga gtggataatg atgagtagta atataactat tgaaatggtt gattcagtct
    34081 ttgaaagagt tccaggagca acttatgcag aagcaaaaga agcattagta atgtgcaatg
    34141 gagatgtaat tgaggcagta atatatttag aaaataaaaa aaatacttgt aattgtaaag
    34201 caaaatctgc taaagaaact atggaagaag tatttggcaa agatggagaa aatataaagt
    34261 ttcaattaaa agagcttctt agaaaaagta gtgtagtgag aataatagtt gaaaaagatg
    34321 gaaaaactat gatgaatatt cctttaacag ttggagttgt tggattagct tttgtaccat
    34381 tagctacttt agttggatta tcagctgctg ttataagtaa atatcgtata aaagttcaaa
    34441 atgaagaaga tggagaaatt gtagatttag gtgaattgaa tgaagaaaaa cttcacgttt
    34501 tgaagaatat gataactaat gcagcaaaag atgtgaagga tgtagtagtt gacaaaaaag
    34561 aagatgacaa agatgtaact gctgacctta tgaaagaaga atctgaaaag aataaagaag
    34621 acgaagacga aaataaatag atataaagtg acttttaaaa aatgaagaga agataattat
    34681 aagaattatc actaacattg acaaatttta tagaatttga tattctaaaa gttgtagaag
    34741 aactattaaa atagcctttc gtgtagacga gaggctttat tgttatagga gggattttta
    34801 tgaattttca agagatgata ctggcgttgc aaaaatactg gtcaaagcaa ggttgtatca
    34861 tgatgcagcc ttatgatatt gaaaaaggtg caggaactat gaatcctaat acttttttaa
    34921 gatcattagg acctgagcct tggcaagtat gctatgtaga gccttcaaga agaccagcag
    34981 atggaagata tggtgaaaac ccaaacagac tatatcaaca tcatcaattc caagttatac
    35041 taaaaccttc tccagataat atacaagaat tatatttgga aagtttaaaa gagattggaa
    35101 ttgacccaag tgagcatgac ataagatttg ttgaagataa ctgggaagct gctacagttg
    35161 gtgcttgggg acttggatgg gaagtttggc tagatggtat ggaaataact caatttacgt
    35221 attttcaaca agtaggtaat attgaatgtg agcttgagac aggagaaatt acatatggat
    35281 tagaaagatt agctatgtac attcaagaag ttgatagtgt ttatgattta aaatggaatg
    35341 ataaaataac ttatggtgaa gtatttaata aagctgagta tgaaaactca atgtacgcat
    35401 ttgaattatg tgatgcagat atgttgttta atctgtttga tatatatgaa aaagaagcat
    35461 taagacttat ggaaaatggt cttgtaatac cttcatatga ctatgtgtta aaatgctctc
    35521 atgcatttaa tacattggat gcaagaggtg caataggagt tagtcaaaga gcttcattta
    35581 taggtagagt tagaaatatg gcaaagactg ttgcagaaac ttttgtaaaa caaagagaag
    35641 aaatgggatt ccctctttta aaggacggtg acaaataatg aaaaattatc ttttatttga
    35701 aatcggtgtt gaagaaatgc catcaagatt tgtaggcagt acactagaac aattaaaaaa
    35761 caatcttagt aaattatttg atgaaaatag aatagctttt gataaaataa atgcgtatgg
    35821 gacaccaaga agacttactt tagtagtcga aggattgagt gatagacaaa atgatttaga
    35881 agaggaaata aagggtcctg ctaagaaaat tgctgttgat gcagaaaata atttaacaaa
    35941 accagcatta ggatttataa aaagcaaagg attaagcgaa tctgacatat attttaaaca
    36001 agttggaaaa gaagaatata tatttgcgac tataaagcaa gatggaaaag aaacttcaga
    36061 agtactaaaa gacatattac cagagactat aaaatctgta gtattcccaa aagctatgcg
    36121 ttggggagga aaaaatctta aatttgcaag acctataaga tggatagttg cattgttaaa
    36181 tgataaagta ttagagtttg atttagaagg aataatatct tctaatgtaa caaaaggtca
    36241 tagattttta ggtgaaagta caatagaagt tgattctata gaagattatt ttgaaaaatt
    36301 agaaaaaaat tatatagttt tagaccaaaa caagagaaaa gaaatgataa gaaaacaatg
    36361 tatagaagta gcaaattctt taggtggaga agttgaattt gatgaagatt tacttgaaga
    36421 ggtaacttat ttagttgaat atccaactgc tttttatgga gaatttgatg tggattatat
    36481 aaaactacca aaagaagttg ttataactcc tatgaaacaa catcaaagat attttccagt
    36541 acttaaagaa ggaaaactgt tacctaactt tatagctgtt agaaatggtg attcttacag
    36601 aatagacaat gttaaagctg gaaatgaaaa agttttagaa gcaagacttg cagatgcttt
    36661 atttttctat agagaagata ctaagagaaa cttagaaagc tacatagaaa aattaaaaac
    36721 tgttgtattc caagtaaaac taggaactat ttacgacaaa actttaagac ttgaaaaatt
    36781 aagtgctgat atacttgata gtttaggttt agtagatgaa aaggcagata ctataagggc
    36841 tgctaaatta tctaaggcag atttagttac tggaatggta ggagaatttg atgaattaca
    36901 aggttttatg ggaaaagaat acgcaaaagt tggaggagag aatgatgttg taagtgaagc
    36961 tatttttgaa cattatcttc caagatttgc aggagatata cttcctaaga ctaatgcagg
    37021 agttgcctta tcaatagctg ataagttgga ttcaatagca ggtttctttg ctataggaat
    37081 acaaccaaca ggttctcaag acccatatgc tttaagaaga caagctttag gtatacttag
    37141 tatacttatg gacagaaaag ttgctgtgga tataaaagta cttattgaac atgctttaga
    37201 caattattct gaattagatt ttgataaaga agaagttgtt gagcaaataa tgaatttctt
    37261 caatgagaga gtaaaaaatc tatttaaaga tttaggaata agatatgatg ttgttgatgc
    37321 tgttttaagt tctgatataa atgatgtttc tgatatgcat atgagagctt tagagcttaa
    37381 taattggcta gaaaaagatg aattagtgga gatgcttact gcatttaata gagtttctac
    37441 tctagctcaa aaagcagaaa gtgataaaat tgatgaatct ttattaaaag aagatgctga
    37501 aattaaactt tacaatgaat ttaaacaagt aaagataaaa gttaatgaat tattaaagga
    37561 taagaaatat ggtattgctt tagatgaatt tgcatcttta agaccagtag ttgataattt
    37621 atttgataca gttatggtta tggataatga tgaagctatt aagaacaata gacttgcttt
    37681 acttaaacaa gtatatgata ctatgctaga aatttgtgat ttatctaaaa ttgtttataa
    37741 ataaaattta aactatttat aagaaataag gctgtctcaa aatagagata gtcttatttt
    37801 tcattgttga gatgatgaaa atatatttga tttcatagaa aaagagtgtc tcataaacta
    37861 aaaagttcat tttgagacac ccatgttttt tgtaagtaaa tataataaac tatattttat
    37921 acttatcagt tattttgttt aaaatattat catttgaatt tacccattca taaaaattgc
    37981 ctgatgatgc gtccgatatt ttataaagca tttcaggaat atcactagct ttaaaatctc
    38041 caagtgattt tcccaatcta gtcttaccta tttcaaaact gcctccaaca aataattcaa
    38101 atgtatctgt agatatacca tcaacattct tctttttacc acataaacct atgctaccaa
    38161 cttgatgaac accacatgaa tttaaacatc ctgatatata taacttaggt gctttattta
    38221 aaatttcttc attattttgt aatctaaaat aatctatgat ttcatgtaat attttctgac
    38281 tattttgtat gcccatttga caaattggaa cacctatgca agatatactt tgttctaatt
    38341 gagaattaca actaatagtt ttacttattt ctaatattct ttttgcttca tttccattta
    38401 aatttaaaat atataatccc tctgtcattc ctagtctaat cataggattt tcaacattat
    38461 ctaattcttt aagtaaagta cttaaatcct ttgttaacaa aatacctcca actggatgta
    38521 tatatacagt gtataaacca tcctgttttt gaggtattag tctagaatct tgtatatcta
    38581 ttttaactcc aggtttagag taatctattt cttcaatatt gagttcaaga ctaccatttt
    38641 ctttttctaa tttatagtat tctttaaatt tttctaagaa tagttcttca ccaagtgatt
    38701 cgaccatata tctaacccta gctctgtttt tattttcata atttccataa tccataaaga
    38761 atttaatcat accttcaaca caatataagg cgtctttcgg ctttataagt tcatcaagtt
    38821 ctaaagcaac tttgggttgt ttacctagac ctccacctaa gaaaactctg aaatatggtt
    38881 catcattttt caaagtagca acaaatccta agtcttgtat actacaatga gcagtatctg
    38941 tgtaacaatt agaataagaa acttttaatt ttctaggtaa atggtatgta gtagcatttt
    39001 tgataaaata tttatcagta gcaactgcat atggagtaac atcaaagact tcactagggt
    39061 caactccaga taatggagat aatccgacat ttctaggata attaccacca ccacctctag
    39121 tgaatatatc attttttatt ccttcttcca tgatatcaac aattgaattt atagataaat
    39181 cgtgtaattg tatagcttgt ctagttgtta agtgtatctt atctaagttg tgtttaatag
    39241 ctatttcata gattttatta agttgatact gagataaaac tccagcagat actctaagtc
    39301 ttatcataaa agattttttg tctctttgag cataaacacc atatccacca gaaaatccct
    39361 tatattgcat tttatttatt tctccattta aaaattttga agaatattct ttaaaattag
    39421 gtagttcatt taacaatatc tttttaaaat tatccattat ttcacctcat tgttagtctt
    39481 gtataaaaat atatctattg tataatagat atatatatta ttatctagtc aggataaaaa
    39541 tataacagaa taattctatt aaaagtaaga ataataagga catagtgagt attttgtttt
    39601 tattttacaa attaagtata atatttttgt tttataaaat ataattaaga taaatagata
    39661 attttgtaat tttaatatat aatatttagt agagtgtggg agtagcactt aatatttgca
    39721 ggaggagttt ttgtatatgg gagaaataat aaatgcatta gatagagccc tagacataat
    39781 tttgctgtta tatcatgaaa agagagaaat gggaataact gaaataagta aggctatggg
    39841 agtatataaa agtactatac atagaacttt ggttactctt gaaaacaaag gttttgttat
    39901 acaaaatgca gagaatggta agtattggct aggaataaat ttatatgcaa taggtatggt
    39961 tgtgggagaa aaaatgtcat tgactgaaat agtaaaacca tatacgaaaa aattaaatca
    40021 agaatttaac gaagtagtta atgtatctat attagaagaa agagctcaag attctccaag
    40081 aagtatcata atacataaag agtatggttc aaatcaatta ctttcagtaa atccatccgt
    40141 tggttcaagt agtgaatgtt attgttcagc agttggtaaa tgtcttatgg catttaatga
    40201 ttctatagat tttgaaaaat atagaaaaac accaatacac aagtatacag aacatacaat
    40261 tgataattgg gatgatatga tgcttttttt agcaaaaata aaagaacaag gatatgctat
    40321 agatgatgaa gaactagaac atggactaac ttgtattgga gcacctatct tagataaaaa
    40381 taataaagct attgcagcca taagtttgtc aggtccaact ataagaatga gagaagggga
    40441 ctttgagtat aagattaaaa gagttataga aactgcaaaa agtatatctg aactttttag
    40501 atgattttta atctcgataa taaaaatagg ctatatttaa attgttattt gtaaatatca
    40561 gtttaaatgt agcctatttt tctttaatct aaaattaaat attcttaaaa tttaaaatgt
    40621 tattgaaata tataagcgaa tgtgttatct tttaattaag caataaaaat agaacaaggt
    40681 tctatactat agaacaaaat tgatgcatat atagtattta tacaaaatat aaatattata
    40741 tatttaaaat taagtaaaaa tattacataa aggggagatt tgagaaatgg aaaaagtcaa
    40801 gttgagtgtt gaaagatgta agggatgcta tctttgtatt gaagcttgca aaaaagatgc
    40861 aataagtctt tctgactaca caaataaaaa aggctttgta actattaaag tcgatgaaga
    40921 aaaatgtatt caatgtggcg cttgttatac aatgtgccct gatttagtat ttgagatatt
    40981 ataaattatt tttattagag gggagaaaag gtatgcaaag tttattaatt aaaggaaatg
    41041 aagctttagc agaaggtgct atacgtggtg gttgcagatt ttatgcaggt tatccaataa
    41101 cgccacaatc agaaatatta gaaatgatgg catggagaca aaaagaagtt ggaggagtat
    41161 ttatccaagg tgaatcagaa atagccagtg taaatatggt tatgggagca agtgcacttg
    41221 gagcaagagc tatgacttct tcatctggtc caggattttc attaaaacaa gaaggtattg
    41281 catattgggt atcagctggt ttgccagcag ttgtagcatg tgtgcaaaga tatggtatag
    41341 gtgatggatt tataggagct ggtcaagata attattggca agcagtaaaa ggcggtggaa
    41401 atggagatta tcatttaatc gtgttagcac ctaatagtgt tcaagaaaat atggatatgg
    41461 catatgaatc ttttgaattg gctgaaaaat atatgcatcc agtacttata ctttctgatg
    41521 ctacaatagg tcaaatggta gaaccttgta tagcaccacc aatgaaagaa tacgatatgg
    41581 ataaagctcc atgggctgca aaaggaacac ctgtaggaga aaaaaataaa gtaataactg
    41641 atataacata ttttgaagac caagatacat ggcaaaaagg gtatatagaa aaaatgagaa
    41701 aagttcaaga agatgaacaa agatgggaag agatagaaat agaagatgct gaagtggtat
    41761 ttgtggcata cggtatttca tcaagaatag cagaaggtgc agttagagat gctagagcaa
    41821 aaggaatgaa attaggtcta ataagaccaa aaacattgtg gccttaccca agaaaagcat
    41881 ttaagaaatt aagtgattca ttgaagggac ttgtaacagt tgaaatgaac atgatggcac
    41941 agatgaagga agatgtaatt atagcatgtg ataatagatt tccagtatat tcagtagcaa
    42001 cagctcaata tatggcagaa gtaaatcaat taatagattt tgctcaacag attatagatg
    42061 gaaaagctaa gcaagaggag gtattttaat tatggctaaa aaagcaccag caataatgat
    42121 gtgtgaaaat atgttctgtg gaggctgtgg acactctata gtcgatagaa ttattggaga
    42181 agtattaaca gaaatggata tatgtcaaga tacaattata tgttcagata taggttgtaa
    42241 tcatatgttt caatttagta tgaatgtaga tgttgtcgtt ccacctcatg gtaaaatggg
    42301 agcagcaatg gcagctatga aaagagttag accagataaa tatatattta caatagctgg
    42361 agatggtgga gcttatgcaa tagggcttgg agaaactatg tcagctgcta ctagaaatga
    42421 taatgtaata tttcttgtta tgaacaataa tatgtttgca atgacaggag ggcaaatggc
    42481 tccaactact atagaaggtc aatatacagc ttctactcca gcgggtagaa attacgcaga
    42541 tcatggttca acatttgatg ttgtaaaagt tatgggaaat ttagatatag catatctagc
    42601 aagaggaaca ataactaacc ctaaagaaat aaatacaaca aaaagataca tcaaaaaagc
    42661 tctagaaaaa caaaaagaaa agaaaggttt ttgcttaata gaagtgcttg taccatgtcc
    42721 aacaaactgg ggattaaagc cagtagatgc tatgaagaga attgaaaatg aacttgttcc
    42781 aaagtatcca cttggagaat ttattgatta gggaggaaat aatatgttga atgaaattat
    42841 atgtgctggt tttggaggac agggagttct tacagcagga aaaattataa tgtatgttgc
    42901 atataaggca gaaaagaaaa ttacatggtt cccatcttat ggaaatgaga tgaggggagg
    42961 aagtgcaaat tgcaatgttg ttgtaagtga tgaaaaaatt gcaaatcctt gtgtaaaaaa
    43021 tccagatata ctattgggaa tgaacagcgt atcagtagat aagtatgaaa gtttaatgaa
    43081 aaaaaatggt tatatgtttg tcaatgaatc actagtaagt aaggatagaa agtacagaga
    43141 agacattaat gttataaaag tacctgttac tgaaatagca caaaatttag gcaatgaaaa
    43201 agctgctaac atttgcatgt taggtgctat ggtaaagagt ttggatttat ttacaaaaga
    43261 agaatttgaa agtggtatgt gtgaatactt tgaaaatcaa ggcaaaggta aattcaattc
    43321 taaaaatgta gaagcatttg aagctggata cgactacgaa tgaatatttt aaatatttaa
    43381 aataattatt gaaatactta tttttatatg ttagtattta attaataaaa tatagaacgt
    43441 cgttctggac aatgggacga agtctttggg tcggaataca agaacggcgt tctgtataat
    43501 agaactaggg ggtgttaaat tgaaagtttt agtaataaat cctggtggta catccacaaa
    43561 aatttctgtt ttccaagatg aaaatgaaat tttgaaaaaa aatataaccc atacaagaga
    43621 agatttaaaa aatttttcta aagtatttga tgaatatgat tatagaaaac aactgatagt
    43681 agatatttta agtagtgaga atcatagtat aaattctttt gacgcagtag ttggtcgtgg
    43741 tggacttatg aaggctataa aaggtggtac ctatactgtg agtgaagaaa tgattgagga
    43801 tatgagaaat gaaataaatg gggaacatgc atcaaattta ggtgcattat tagctaaaac
    43861 tatagctgat gaaataggag tacaatcatt tgtagtagac ccagtttctg tagatgaatt
    43921 tgatgatgta tcgaggatta caggaatatc agacatagaa aaagcaagtt ggttacatgc
    43981 attaaaccat aaagctgttt caagaaaaat tgcacaaaaa ctagggggaa aatacgagga
    44041 ttataacttt attgtagctc atttaggttc aggaatatcg attgtagcac ataaacaagg
    44101 caaaatgatt gatggaagtg gtggtaggtc tgatggtcca ttttctccag aaaggagtgg
    44161 tggattactt gcatatcctc ttatagaatt gtgttactcc ggaaaatata ctcatgatga
    44221 aatggtcgca aaagtaagtt cgattggggg aatgtacgat tatttaggaa caaaggacat
    44281 gatagaaatt gaaaacagaa tcaaggaggg tgatgaaaag gcaaaactta taatggatgc
    44341 atttatttat caagtagcaa aagaaatttc tatgtatgga gcttcacttt cagggaatgt
    44401 agatagagtt atcttgacag gagggatatc tcactcagaa atggtagtca aaggagtagc
    44461 agaaaaagtt tcatatctag ctccaataga gatagtacca ggagagatgg aaatggaggc
    44521 acttgctcta ggggcactta gagtacttaa tggagaagaa atagcaaaaa cttattaata
    44581 tttaggagaa agagtatgtt aaaagatttt aataatttat tagaagaggc taaaaagctt
    44641 gaacctgtta ttgtaagtgt tgctgttgca gaagacaaag aagtattaaa ggctgtgaaa
    44701 tcagcaacag atttaaacat tataaagcca attcttgtag gagacaagga taaaatagaa
    44761 agtatatcaa gagaaattgg attaaaaggt catgaaataa taggttgtca aaatcccgat
    44821 gaatcagtta aaaaagctgt agagatagtt aaaaataagg aagctaaagt tcttatgaag
    44881 ggattagtaa atacaagtgt ctatatgaga gctatattaa ataaagaaac gggtcttaga
    44941 acaggaagat tattaagttt gcttgcagta tatgaattac ctcaatatca taaacttctt
    45001 tattgtactg atagtggaat aaatgtatcg ccaaacttaa atcaaaaaaa agatataatg
    45061 acaaatgcac ttcttactat gaaaagtata ggcatggaaa atcctaaaac tgcgatactt
    45121 actgcaaatg aaatggtaga ccctaagata caatctacag tggatgccaa cctacttgta
    45181 gagatggaaa aatcgggaga aataccaaag tgtatagtgg aaggtccaat agcatttgat
    45241 gtagcatttg atgcacatgc agcagaacat aaaggcatta aaagtaatat tgctggtgat
    45301 gttgatttat tagtatttcc aaatatagaa gcagggaata tattaggaaa gtcatggctt
    45361 agatttaata aagctaagtg ggcaggtata gttttaggag caacaaatcc gataatttta
    45421 ggttcacgtt ctgacacagc tgaaataaaa ataaattcaa tagcattagc gtgcctagca
    45481 tcacaataag aaattattat taaggaggaa aaagtattat gaaatatgca aaaagaatgg
    45541 atatggtaaa agcttcagct ataagagatt ctcaaaagaa aatagctcag aaggtagcaa
    45601 gtggtggaac tgttatatct tttgctgcag ggcttcctga cccaaattta tttccaatag
    45661 aagagataag tgaaataact caaaaagtac ttaatgaaag gggaaaattt gccctagcat
    45721 atggacctac taaaggtgaa gatgagttgt tagatctatt agtaaaaaga atgaaagaag
    45781 aagaaaatat tgatacaaaa gcagaaaata ttataataac tactgggtca caacaaggga
    45841 tagcattaag tgctatgatt ttattagaaa agggagatgt agtagttaca gaaaatccaa
    45901 gttacttagg tgcaataaat gcatttagac cttatgaatg tgatttttta ggagtagata
    45961 cagatgaaga aggaatggta acagatgatt tagacaaatt attatctgaa aattctaaca
    46021 taaaggtgat atatgtaata ccaacatttc aaaaccctac aggaaaaaca tggtctttac
    46081 aaagaagaaa agattttatg gaagtcgtga ataaatatga tgtcatagta atagaggata
    46141 atccttatgg agaaataaga tttacatcag aacctctacc tacacttaaa tctcttgata
    46201 ctaaagataa agtattgtac cttgggtcat tttcaaaggt attatgtcca ggatttagag
    46261 ttgcttggat gtgtggtaat gtagacatca tagataaggc agaactttta aaacaaggta
    46321 tagatttaca gtcaaatcaa ttttcgcaag tacaagtaat agaattttta aagaaataca
    46381 acttaaatga acatatagaa aaaataagag cagagtataa gaaaagatgt ctgctaatgt
    46441 tagatgctat gaagaaacat ttcccagagg aagctaaata tacagaacca gatggaggaa
    46501 tgtttatatg ggttgaactt cctgaaagta taaatgtaga tgatttatta gataaagcca
    46561 ttgatgctgg agttgcttat gtttctggag agtccttctt tgcaaataat ggtccaaaaa
    46621 atactatgag acttaactat acaacaatgt cagaagaaca aatcgttaaa ggtgttgaga
    46681 tacttgcaga agttataaaa aaagaactca attatgcttg tgaataaata taaaaagtga
    46741 gggtttaaat atgggagaaa aagaaaacgg tataaagttt ggaaagttaa tgtttcaact
    46801 tgttattata gcaatatctt gggaattagt ttatattata ccatttatcc aatatacatt
    46861 atatgatcca atcctaaaag cattagaatg tacaaacact caactaggtt ttctacttac
    46921 aatttatggg ttaggtaata tatttggagc tcctatagga ggctggttag cagatagatt
    46981 tgattataga aagataattt taggttctgt atttcttaat ggagtagtat catttttatt
    47041 tgcatttaat atgaactatc catttgcagt tgctacttgg gtaggttgtg caatcacatc
    47101 attagttatg aactatcctt ctatggtaaa aatacttaga gttataggaa aagataatca
    47161 aggtaaggtt tatggattta atgaagctat ggttggagtt tctggagtag taatgggagc
    47221 aatattctta tatatttata catgctttgc aactcctaca ttgggtatga gatgggtaat
    47281 gatatcttta ggaatattat caatagcaat gtgtccagta ttatggtttg taattaaaga
    47341 tgtagatatt aaagaagaaa gagaagaagc aggtgaaaaa atgtctgctg gtgattttat
    47401 aacagtacta aaatcaccaa atacttggct agtaggaata agtatattct gtgtatattc
    47461 attcacagtt acaatgtctt attttacacc atatataaca tctgtacttg gaggttctgt
    47521 agcattatct ggtgcattag caataataag acagcatggt ctaaaattat ttggagcacc
    47581 atttggagga tattgtgcag acaaattaaa atctcctaca aaagtacttt taccaatata
    47641 tgtatttggt atagcagtaa tagttttatt cctagtatta cctgcatcaa ctccaatgac
    47701 tatattcata gctttaacat ttgtagtagg tatattaggt tacatgggaa aaggtatata
    47761 ttatgcagta caagatgaag taaaagttcc agttaaatat tcagcaacta ctataggtat
    47821 agctgcagct ttaggatttt caccagatgt attccaattt gcattaatag gacactggat
    47881 agatacttat ggcaataaag gttacacata tacatttata ttccaaatag caattctagt
    47941 tattggaata ctatcttgtt tatatatatt aaaggttaaa aagagaagag caagtaaatt
    48001 agaagcttaa atattcaatt tggtaattaa gtatatataa atacaatact tattttgatg
    48061 aatgtgattg tataaataac ataaaaaata tcaatagatt aagttttata ataatgttta
    48121 gagaataaag tataaaaatc aaaatgttat caagttttct aggttttaac ataaagttac
    48181 ccctgaaggt gtaaaattga gtggcaatta ttatctattt tcttacctac ataaacctat
    48241 ttaatttaaa ttctaagaga ttttaaaaat agatggtagt tgtactcaat tttaaacctc
    48301 ataataaata cgaaaattta aaatctaact agatactatt taattatata ttaataaata
    48361 tatattgtac tatttatata ataataattt caggcttttc attatatgta ttccaattta
    48421 tattgtttga ttattattca aacacacgtc gttaaaaatt ttataaattt atgtttagat
    48481 atgattaata ctcttgattt tagaaataaa tatttgtaga ttgtagatta aagataatat
    48541 aaataaatag aaggtagatt ttttagatat attaatataa agattatata aaatattgaa
    48601 atatagctgt ttaaattatt gtctataaat ataaaatgaa tggtggtgag ttaagtgacc
    48661 gatttagtta acaccattaa tggaattgtt tggtcacccg tattagttgc aatgtgtttg
    48721 tgtataggat tatatttttc attgaaatta aaattttttc aaataagaga tgtaaaagaa
    48781 atgtttactc tcttgcttga aggagatagt tctcatgttg gtatatcatc atttcaaggt
    48841 tttgctacat ctatggctgg aagaataggg actggaaata tagctggtgt agctgtagca
    48901 atagcaatgg gaggtccagg agcattagta tggatgtgta taatggctac attaggttca
    48961 gcaactgcat ttgtagaatc tactctagct caaatatata aagatgagca tgatgggcag
    49021 tatagaggag gacctccata ttattttgaa aaaggtcttg ggtggaaaaa gtgttcagtt
    49081 ttattttcaa tagttgcaat aataagttat acatttttta tgcctggtac acaatcaaac
    49141 actttatatc tagcaatgaa tcaagcattt ggattttcaa aaatgacaat agcagtagca
    49201 tcttctattg cattagcgat aataattttt ggaggaatta aaaggattgg tttatttgct
    49261 gaaaaagtag tacctataat gggtggagca taccttatta tgacattagt aataattata
    49321 acaaatatta gtttagttcc agaggctatt gtaacaatgt ttaaatctgc atttggattt
    49381 ggttcagttt ttggaggaat gctaggttca gcaatatctt ggggagtaaa aagaggtata
    49441 tactcaaatg aagcaggaga aggttctggg acttatggtg cggcagcagc agaagtgagt
    49501 catccagcca aacaaggatt agttcaagca ttttctgttt atgtagacac attattaata
    49561 tgtatggcta caggtattat gattgtaata acaggaatgt ataatgttac aggtgtttgc
    49621 acagcactgc caggtgtaga accgggacca caatatgtac agagtgcaat aaatacatta
    49681 catccacaat taggtgatat ttttatagca atagttttat tattatttac atttacaact
    49741 ttattagcct tctcatatat gatggagact aatgtatctt acttagtaac tagaattaaa
    49801 gcagaaaaac atgaaaagta cataattaat gtctgtagat ttatgcttat agcatgtgca
    49861 gcaatgtgtt gttttataga accacttaca agctgggcat taggtgatat atgtataggt
    49921 gtattaacat atataaattt aattgccatc tttacactaa aaaaaccagc tataaaggca
    49981 tattatgatt atataagaca gaagaagatg ggaataaaaa ggagtgatag aacttttaac
    50041 cctatagagt tagatataag aaatgctgag ttttgggaaa atagatactt aaaagaggat
    50101 aagcatgagt taaattaaag ttataataaa atataaaaat tactaaataa atttagtggg
    50161 aggtaagatt ggtatgaaag aaagaataat acaagtggct gattcaaaga aagaaaaaat
    50221 tctagggcta tgtcaatctt tatatgatga accagaaatt gctttgcaag aatataaatc
    50281 tgctaaaaaa atatcagaat ttttaagaga agagggtttt gatgttgagg aaaacttggc
    50341 aggtatggct acagctttta aagcaaccaa gaaaaatgga gatggtccta aaatagcatt
    50401 tatagcagaa tatgatgctc ttccaggcaa tggacatgca tgtggacatc atttaattgc
    50461 atctatggga gttggagctg gaatagctct ttcaagtata ctggatactt acaagggaga
    50521 agtaagtata attggaacac ctgctgaaga aactggagat ggaaagcctt acttgataga
    50581 acatggtgta tttgatggct atgatgcagc aatgatgata catccaaatt caaaaacttg
    50641 tgtaacacct gaaattatag caataggagg tctagatttc atatttactg gaaaagcatc
    50701 tcatgcagga gctaagccat ataacggaat aaatgcttta gatgcagtag tattactata
    50761 taataatata aatgcactaa gacaacaatt agtagatgga acgagaatac atggtattat
    50821 actagaagca ggaactgctg caaatgtaat acctgatatg ggaaaagtaa gattagagat
    50881 aagggcaaaa gaacaaaatt actttgatga agtagtagaa aaagtgaaaa attgtgctag
    50941 aggtgctgca atagccactg gatgtgaact tgaattttat cactttgaac caacttgcca
    51001 aggattaaat gaaaataaag ttttggtaga catatttaca aagattatgg aggaatttgg
    51061 aatatatgaa gatgaacaag taatgttagg ttcaacagat atgggaaatt taagtcaaat
    51121 aatgccatgt atacatcctt tgatgaagtt ttctgaaaat ggagaagaac tacatacaaa
    51181 agaatttttg gaggcttcta taaattcata tgcaaaagat agagtaattg atggtataaa
    51241 aatattggct ttaacaggat ttaatttatt tgaaaatcca gagttattga aaaaaatgaa
    51301 ggaagagtag aacttagact atttttaatt atactcttta aaataagaag agtgtctcaa
    51361 aatgaacttt ttagtttatg agacactctt ttttgtatga aattaaatat atttttatta
    51421 ttttaacaat gaaaaagagg cttatctgtt tttatatgac cttttttaac ttgtagcaca
    51481 aaatatcatg aatgattaca attcgaatga taaaatcgat tataagatat ataggagggg
    51541 tacatatgga aactttagaa gtaagaaata ttgaattgag tggtacaaat tatgagatag
    51601 gatacagact aggagaattg gttgctaata tgccagagat aatagaaggt cagattaata
    51661 aatctaatct ggtaagcaaa aaagaagaaa aagagatgat agagttgttt gataaatatt
    51721 gtccaggtct taatgaagaa ttgcaaggtt ttgctgatgc aattcaagtg aattgtaatc
    51781 aaattttata ttatactatg acttatctta aaccaggttg tagtcaagtt gcattagcac
    51841 cagaattaac tgaaaatggg catgtactat ttgcacgtaa tttcgatttc tcacacaata
    51901 tggaggattt tgttttatgt aaaactaagg taaatggaaa atatgcacat ataggtacta
    51961 ccgttatgca atttggaaga ggtgaaggta tgaatgaatg tggcttaggt gtaagtcagt
    52021 catcatgtgg tattcctgta ggcaattcag atggtttaag aaaaccagca attgtaggtt
    52081 tacagttttg ggctgttatt agatatttgt tagaaaattg caaagatgta gatgaagcat
    52141 tagaatattt aaaagatatg ccaattgcat acaatattaa tttattgctt gcagataagt
    52201 ctggaaacat tgcacttgtg gagactttag atgggaaaaa agaagtaaat ataatcaata
    52261 gtttagaaag taaaagagaa tattttttac actctactaa tcatacacat attgataaac
    52321 ttcataaatt agagccacaa tcaatgaaaa attctattca tagatataaa ttaattaaag
    52381 aatatataaa taagtctaaa aaaattggag agaaagagtt aatgaattta ttgtcttcaa
    52441 aatatccaaa tggcttatct tgtaattact ataatgattt ttttggaact ttaaaaagta
    52501 tagttatgga tttaaatata ggaaagttta atattttatg gggtggacta gagaataaat
    52561 gggagagcta ctatttaaaa aatgacatta aatctataac acagaggata aacataaata
    52621 ttgaaaaagc accatctgac ttttttgatt tcattgaata aaaaatgtat ttaattattc
    52681 taaataatta ggatatataa atcaactaaa agtttttatt tatcgtattg aattagttat
    52741 aatattttag tatagtaaaa aatagtgcta ttttacatat ttaaagagtt taagtagaag
    52801 agaggtgcca tattggatta cttaaagtat tttgaaaaag ctgtaatgta tattgagaat
    52861 aatttacatg aaaatataac tgtaaatgat gtggcaaaag aaactggata ttcttattat
    52921 catttaacac gcttatttaa gtctatgttt ggtgagagtg taggaagtta tataaaaaaa
    52981 agacgattag taagtagtac aaaagaactt ttatatagtg ataaaaaagt gatagatata
    53041 gctattggta gtggatttga atcttcggaa gcatttagca gagcatttaa atctatatac
    53101 aaggttagcc ctatagaata tagaaaaaat agaattgatg tatttgttgg taaaaagaaa
    53161 aaattagagt tagattttat gagacatctt gttggaaata taacgattaa accagttata
    53221 aaagaaatag aaaaaataaa ggtaataggt ataaaggata aagtaatttt agaaaataat
    53281 tcattacctg acttgtggga gaaattcaga aaagtacatc atattgtccc aaatactttg
    53341 ccatcaaaga gagtttttgg aatctgtgaa gcaatctctg aaatacacct agttagtgaa
    53401 agtatggaat ttaatgagat aataggactt gaagttaata gttatgatgt gattccaaat
    53461 tcatttgttt caaaaactat taaggaagga aagtatgcta tatttactca tactggtagc
    53521 ttagataatt tagacaaaac ttatgaatat atatggggta cttggttttt aagttcaaaa
    53581 gaagaacttg atataagaga tgattttgaa gtatatgatg aacgattttt aggtcctagt
    53641 aatgtgaact cacaaattga tatttatata cctataaaat aatctataag aaaactaaaa
    53701 aataatttga ttaagaaata gatgttcgta aaagagcatc tattttttat ttttatcaga
    53761 tttagataat tttaataata aaaga
//
LOCUS       DAEPUT010000020        49279 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.020, whole genome shotgun sequence.
ACCESSION   DAEPUT010000020 DAEPUT010000000
VERSION     DAEPUT010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49279
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.020"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(531..1043)
                     /locus_tag="KRL22_001309"
     CDS             complement(531..1043)
                     /locus_tag="KRL22_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271811.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNVILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            1596..2474
                     /locus_tag="KRL22_001310"
     CDS             1596..2474
                     /locus_tag="KRL22_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HBH1271812.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNKLIYSNMIDKKT
                     QNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPYN
                     LEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKDA
                     KFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLRY
                     PETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEGE
                     IELPDPIIMENDKLMK"
     gene            complement(2787..3566)
                     /gene="hisJ"
                     /locus_tag="KRL22_001311"
     CDS             complement(2787..3566)
                     /gene="hisJ"
                     /locus_tag="KRL22_001311"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HBH1271813.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(4112..4462)
                     /locus_tag="KRL22_001312"
     CDS             complement(4112..4462)
                     /locus_tag="KRL22_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HBH1271814.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(4478..4894)
                     /locus_tag="KRL22_001313"
     CDS             complement(4478..4894)
                     /locus_tag="KRL22_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HBH1271815.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAISDSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(4913..5104)
                     /locus_tag="KRL22_001314"
     CDS             complement(4913..5104)
                     /locus_tag="KRL22_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HBH1271816.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(5255..6070)
                     /locus_tag="KRL22_001315"
     CDS             complement(5255..6070)
                     /locus_tag="KRL22_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBH1271817.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(6117..7055)
                     /locus_tag="KRL22_001316"
     CDS             complement(6117..7055)
                     /locus_tag="KRL22_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1271818.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSAGVNKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIS
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(7052..7924)
                     /locus_tag="KRL22_001317"
     CDS             complement(7052..7924)
                     /locus_tag="KRL22_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1271819.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(7949..9877)
                     /locus_tag="KRL22_001318"
     CDS             complement(7949..9877)
                     /locus_tag="KRL22_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HBH1271820.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKDTLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(9989..10366)
                     /gene="gcvH"
                     /locus_tag="KRL22_001319"
     CDS             complement(9989..10366)
                     /gene="gcvH"
                     /locus_tag="KRL22_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBH1271821.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(10453..12579)
                     /gene="cdhC"
                     /locus_tag="KRL22_001320"
     CDS             complement(10453..12579)
                     /gene="cdhC"
                     /locus_tag="KRL22_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HBH1271822.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(12636..13442)
                     /locus_tag="KRL22_001321"
     CDS             complement(12636..13442)
                     /locus_tag="KRL22_001321"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH1271823.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(13492..14859)
                     /locus_tag="KRL22_001322"
     CDS             complement(13492..14859)
                     /locus_tag="KRL22_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HBH1271824.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(14890..15834)
                     /locus_tag="KRL22_001323"
     CDS             complement(14890..15834)
                     /locus_tag="KRL22_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HBH1271825.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(15854..16624)
                     /locus_tag="KRL22_001324"
     CDS             complement(15854..16624)
                     /locus_tag="KRL22_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1271826.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(16680..18065)
                     /gene="lpdA"
                     /locus_tag="KRL22_001325"
     CDS             complement(16680..18065)
                     /gene="lpdA"
                     /locus_tag="KRL22_001325"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH1271827.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(18109..18990)
                     /locus_tag="KRL22_001326"
     CDS             complement(18109..18990)
                     /locus_tag="KRL22_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBH1271828.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRNMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(19026..19700)
                     /locus_tag="KRL22_001327"
     CDS             complement(19026..19700)
                     /locus_tag="KRL22_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HBH1271829.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(19737..20609)
                     /locus_tag="KRL22_001328"
     CDS             complement(19737..20609)
                     /locus_tag="KRL22_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HBH1271830.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(20701..21333)
                     /locus_tag="KRL22_001329"
     CDS             complement(20701..21333)
                     /locus_tag="KRL22_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HBH1271831.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(21438..23114)
                     /locus_tag="KRL22_001330"
     CDS             complement(21438..23114)
                     /locus_tag="KRL22_001330"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBH1271832.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(23363..24142)
                     /locus_tag="KRL22_001331"
     CDS             complement(23363..24142)
                     /locus_tag="KRL22_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1271833.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(24452..26371)
                     /gene="cooS"
                     /locus_tag="KRL22_001332"
     CDS             complement(24452..26371)
                     /gene="cooS"
                     /locus_tag="KRL22_001332"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH1271834.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(26978..27889)
                     /locus_tag="KRL22_001333"
     CDS             complement(26978..27889)
                     /locus_tag="KRL22_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH1271835.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(28005..28583)
                     /locus_tag="KRL22_001334"
     CDS             complement(28005..28583)
                     /locus_tag="KRL22_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH1271836.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRVIDEIPE"
     gene            28809..29732
                     /locus_tag="KRL22_001335"
     CDS             28809..29732
                     /locus_tag="KRL22_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1271837.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQDSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(29904..31046)
                     /locus_tag="KRL22_001336"
     CDS             complement(29904..31046)
                     /locus_tag="KRL22_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1271838.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALKLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(31064..32818)
                     /locus_tag="KRL22_001337"
     CDS             complement(31064..32818)
                     /locus_tag="KRL22_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HBH1271839.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKQSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            32954..33160
                     /locus_tag="KRL22_001338"
     CDS             32954..33160
                     /locus_tag="KRL22_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271840.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(33165..34088)
                     /locus_tag="KRL22_001339"
     CDS             complement(33165..34088)
                     /locus_tag="KRL22_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271841.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIVDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(34342..36042)
                     /locus_tag="KRL22_001340"
     CDS             complement(34342..36042)
                     /locus_tag="KRL22_001340"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBH1271842.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(36454..36867)
                     /locus_tag="KRL22_001341"
     CDS             complement(36454..36867)
                     /locus_tag="KRL22_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH1271843.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(36933..39311)
                     /locus_tag="KRL22_001342"
     CDS             complement(36933..39311)
                     /locus_tag="KRL22_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH1271844.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKSGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            39630..41081
                     /locus_tag="KRL22_001343"
     CDS             39630..41081
                     /locus_tag="KRL22_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HBH1271845.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(41285..43798)
                     /locus_tag="KRL22_001344"
     CDS             complement(41285..43798)
                     /locus_tag="KRL22_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH1271846.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNNYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETDYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEDCIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKVLDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNEESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(44021..44842)
                     /locus_tag="KRL22_001345"
     CDS             complement(44021..44842)
                     /locus_tag="KRL22_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1271847.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(45360..45836)
                     /locus_tag="KRL22_001346"
     CDS             complement(45360..45836)
                     /locus_tag="KRL22_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HBH1271848.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIIYDNGKLKDYNVSFLD"
     gene            complement(45871..46449)
                     /locus_tag="KRL22_001347"
     CDS             complement(45871..46449)
                     /locus_tag="KRL22_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH1271849.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGNEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(46553..49153)
                     /locus_tag="KRL22_001348"
     CDS             complement(46553..49153)
                     /locus_tag="KRL22_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH1271850.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFLEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTAPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLGTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHSNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNAFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
BASE COUNT        15085 a         9392 c         5482 g        19320 t
ORIGIN      
        1 tttttgacac aatcgttttt tattcagtca tttaatattt tcaacacaat cattcttaca
       61 ttctattatt gtttgttttt gatacaactg tttttattca gtcatttaat attcttgaca
      121 caattattct tacattctat tattgtttat ttttgacgca atcgtttttt attcagtcat
      181 tttatatttt cgacacaatc attcttacat tctattattg tttatttttg acgcaatcgt
      241 tttttattca gtcattttat attttcgaca caatcattct tacattctat tattgtttgt
      301 tttgatacaa ctgtttttat tcagtcattt tatattttcg acacaattat tcttacattc
      361 tattattgtt tatttttgac gcaatcgttt tttatttagt cattttatat tttcgacaca
      421 atcattctta cattctatta ttgtttgttt ttgatacaac tgtttttatt cagtcattta
      481 atattctcaa cacaattacc ttttcattca atcaaagtaa tctttaagca ttatttttca
      541 agctcatcaa agtaattata tacgataacc tcacctgtct ctttatctgt agtctttata
      601 atgcccttag ctccatttac ctcttctttt gtaaattcat catctaacac aactttgaat
      661 ttatcttcct ttccataacc ttgttgaaat tcatctctca aaattacatt tttttctgct
      721 tttggcttca actcaaattc aattccagat ttcatttcat caaaataatt taatactaca
      781 acctcattat tcattttatt agttgtcttt ataatccctt tagctccatt tacttcttct
      841 tttgtaaatt catcatccaa tgttatatta aatttgtctt cttttccata ttcctcttga
      901 aaatccctct tcatttcatt gtatttagtt tcaaactctt tactcttgtt taattccata
      961 gctgatacat ttgtcaatga tgctccaatt gccattactg ttaatgccat tactatacca
     1021 cttttaaatt tttttacttt catatcttac ctcctaaatt aaatgttctc aatgaaatta
     1081 tataaagaaa atcctaagtt ttacagtttc attcttgtaa ctaaaattac tattatgtaa
     1141 ccaaactttt tgcttcaact attccttaaa agttgctttt ttgaggaata gttgaagtta
     1201 aataattaga ttttatctat atttatagat ttaaaatcaa atttatccat ataaataaat
     1261 acttattttt gcaaaataaa aatttttaat tactccaatc cttcttattt acttaaaatc
     1321 ctatgataag aaatttaaaa gtctttacct tctttaacaa taatttattt acttttaaca
     1381 tacaaaatat agagagtata tcaaaatcat tttactgaat attctaaaaa taagtacccc
     1441 ctattagtat atatatttac atattaaaaa aaagttttaa ataaagttat attttttaca
     1501 acagttttgt aattaaaaac atattgaagg taaatttaaa ggtactatat actataaata
     1561 tgtcgacaca ataaatttaa aaaggagaac taaatatgaa aaaaagatta ataataatga
     1621 tattgtctgt tgtcttagta ctatcaagta tacttacgat atttgcatat tcaaatatta
     1681 aatataataa taaattgata tattctaata tgatagataa aaaaactcaa aatagtgtaa
     1741 aggaaatcct aaaagaaaat aaaattaatg aaaaagacat agatacattt attaaagcag
     1801 tcaataatta taataaattg caagttaaaa tacttcaaaa taatataaat atatctaaat
     1861 ctggatattc ttcaatcaat gcaaaacaag ttccatataa cctagaaaaa ttgcaagata
     1921 attgggtgaa aaaattccct gattatatgg atgtaaattg tagaataact gcttttagac
     1981 tttttaaaga ttttataaat tcaaataaga aatttactgg agactctatt gatttgaatg
     2041 tcgacttgga cactataatg aataataaag atgctaaatt tagcaccaaa gatgtagaaa
     2101 aatttatcaa cttcttttct gcaataccag ctaaagatac agatgataca atcaaaattg
     2161 cagaacaaat aaaaaatgaa tggaaaaaaa gaaaaatatc ttttaaaaat aataaaaata
     2221 tatctattat aaatggattt cttcgttatc cagaaactaa aaatgtattt ataggtcata
     2281 caggcatatg tattaaaact aaaaatggca ttctattttt agaaaaatat ggtgttacat
     2341 caccttatca agttactaaa tttaaaaata aagaagatgt aaaaaattat atgtttaata
     2401 gattgaagat gtcagaaggt gaaattgaat tacctgaccc tataataatg gaaaacgata
     2461 aacttatgaa ataataactt taaacgcaaa atagtattta taattactaa gtcaatataa
     2521 tagagaaggt ctatagattt gtgtaaatac aagcttatct acaatcttat ataagaatgt
     2581 ttatataaat aagatagatt aattctaagt cctattattc tattgaattt tattattatt
     2641 ttatttagat tctattgtta ttttacttag aacttattat tattttgttt aagttctatt
     2701 actattttca atcatataaa tttacaaaag actgtacata aatttatttt atacaaactt
     2761 atctacagtc ttttgtgtga atatatctaa ataatgtcgt atttatttat ttcctctgca
     2821 cagtgagaat cagaacctaa aactaatgga atatcgtatt tttttaccaa ctctaataag
     2881 tatccatcta tataaggctc tttgcagtac tcttttctat ttccagaaac attataatca
     2941 agttcataac ctttttcttt aattaacttt attaactctt caagaattgt atttccttta
     3001 taatcgtatg gaaatacctg attaaacttt ctaactaaat ttaaatgacc tattcttttt
     3061 ggtttatgta tacctaaatc tgaatttaca gcttttatca atgtttcata atacttatta
     3121 taaacagctt caatacttcc taatttgtcg attaaatttt gaaactcttc tacactgtaa
     3181 tctacacaat aataatcatc atcaatttta attatatgta ctgataaaag agagtcttct
     3241 aattcctttc catatttatt taaattctcc tttatccctt cttcgtatcc ttctataaaa
     3301 tccacttccg acccaacatt tatcttgatt ttaccctcat acttttcttt caacttcttg
     3361 acatcattaa aatactttgg taaatcttca atactcatac aactatcatt ttcaggagca
     3421 gggtctctaa atccatttgc atacggaaaa tgttctgtaa atgtcatttc tgttattcca
     3481 acatccattg ctctttgtac atatttttca aaatcatcct tacttccatg aggacaataa
     3541 ggtgaatgta tatgaccatc tttcataaat aattcactcc ttttttaaag aaaaaatcta
     3601 atataaatgc ataaattttt taacttcaaa ataatatttt taatcatgct aatttttatt
     3661 atatctaata ttagagtaat tttaaactgc cttttaagta tcttatcatt agtactattt
     3721 tcaacttaac attaatatta ttttttaact taacattaat actatcttta aatagtaata
     3781 ctcaatatat aattacttag catcaaataa ctcaaattgc ttgatgaggc ttttgcagta
     3841 tttaaagaat atataattat ctaacattaa ataatccaac cttgtaataa aatttactca
     3901 ttaaagtata ttacagaaaa tacctcaaaa taaacttttt agttcatgat atactctttt
     3961 ttgcatgaaa ttagatatat ttttatcatt tcaacaatga aagggaggct tatatccatc
     4021 tttagacaac cccttagata aaatttttaa taattaaaca tcacaaaata taaaaatcgc
     4081 ttatatcaaa cgtataagcg attaattata tttacatatg ttttttagcc tctaacaaca
     4141 ttttattagc ttcttccata tactctatag ccttttcaat actctttgct gtttcttctt
     4201 ttccaatagc tctagccttt tcaacccact ctctaaatcc ttcttcatga gtttcattgt
     4261 gatttatcca atgtactaaa agtattttta aagttttttc atccttagac tctgatgatt
     4321 cctcatgact atgttcgtgg tcgtggtcgt gagcatggtc atgtggatgt tcatgacata
     4381 tatctccatg agtatgttcg tggcagtggt catggtcatg atgtccatga tgatatctta
     4441 caatctcttt atcaaaaatc attagttatt ccccctgtta ttttatatta aactcttttt
     4501 ttataaggtt tacagaatct tttacaagta gtgctaatgg tttaccttct aatccaacta
     4561 actccacatt ttctggcata ataggtaaaa gtatcttaag tgcctcactg tctgaaatag
     4621 cttcacttat attacaagta acttctccca tcatagaatt aggtattatt acagaaatag
     4681 gtgcaactat tatatttgct tttttagctg atactactat agcattttcc cctgtagctc
     4741 ctttattagc atgagctttc atcatagaac tagttgctat agaattagtc cctagtgcat
     4801 aaatttctac atatgtaggt aactcttctc tcaaagaaga aactatctgg gctccaatac
     4861 ctccacccat tccatctatc actgctatta tcatatgaaa ttcccctatt aattaatttt
     4921 cttgtattat tatcttatgg tccatcaatc ttatttcttt aattatccca tctattatct
     4981 tttgctctcc taataaatcc gttaaataaa tctttccatc acaagggtct atattaacca
     5041 cattttccat aaccttttct aactcattat tacttttaca aatgaaagct gatgattcac
     5101 acatataaat ctcctcctaa tatgattttt attaaaaatc aaaaaaagat tcccttaggt
     5161 atttcaatac accaaagaaa ccttcatgat ttcagttttt gtatattatt ataccttaag
     5221 tatatcactt taatttatgt aaagtcaatt aaagttaacg ctttttatta tactcttcat
     5281 tcttgtattt ttcatatagt tctttaacta attgcttctc ataatcagtc aaatcgccct
     5341 ccacaaactc aacattaaat tgttcagcta atccctttac tatgtttttc tgtagaatat
     5401 ctatgtctat ttttctgcca atttcatttt ctattccact tgctttttta gctgtaaatt
     5461 tcatagctct ttctttcaat tctggtgtct tagtttttat taatttaaac aatttttcta
     5521 catcaaaatc cagtattatt gaaccatgtt gtaataaaac accatctttt ctgctttgag
     5581 cacttccaat taccttctta ttattaatag taacttcata tgatgcatgt gcattaaaac
     5641 atgcagctga taaattttcc ctacttattc tctcgcctct atttaaatta tctgtttcta
     5701 taccacttag attcaaccct ttaactagac cttcacttat atatctataa gataggttga
     5761 tgctcttatc gattaaagga ttatcttctc ctataattat actataagtt agctcattat
     5821 catgtaatac agctcttcca cctgtaattc ttctagtata gtctatattc atacatctac
     5881 acttatctaa atctatctca tcttccaatt tctgaaaata tcctatactc aaacaagctg
     5941 gttcccatgt ataaaatcta agagttggct tattatgtcc cttcttatat gcagtaaata
     6001 tagcttcgtc aattgccata ttcattgctc cttcatatga tttattatgt ataactctcc
     6061 actgattcat gattattacg cccccatttt tagtataaat atatcctaga aatcctctat
     6121 agatttattt ctcttattgc taaatctatc tcactttgat ttaaaggtct tgaatagttg
     6181 tatatagtac ttcctggtct ttcattatag tatggtctat tacaatcctt acaacctctt
     6241 atttcaaaag gatagccttt gtttatatct tttaaaatat cattgtcaag ctttatacta
     6301 tttaagtatc catttttaaa cttaaaatac tcttttggat aacctttatt tatcatataa
     6361 gacattaact gtacccttct ataactttct atgcttggtt gacttatctt ttccatttta
     6421 gttcctctaa ctggagtaaa tgcaaataaa ctaatcgtta catcattttc ctttaaataa
     6481 gtatataaat tgtatatatc ttcatgactt tcacccatac caactattat atgtgtactt
     6541 attttattgg gatatgattt tgacatttca gttataaatt ttaacttttc atcatagtta
     6601 tttcctttta ttttttcata tagttcttta tttgctgcat ctattgctat tcctatttta
     6661 tttactcctg ctgaaaaaaa cttctttatc tgttcatcat tttctaattt tgcagatagt
     6721 gaaattggca tgtctatctt accacttata tagtttataa agtctaaaac agagttatgt
     6781 gcttcttcac ttgccattga ttgaatacat attctcttta tattttttcc tttataagct
     6841 tttaaagcat ctaatatttc ttcttttgaa aactctggcc aaattactct tgataattta
     6901 tcttttctag tactactttc tattgattga gaacaaaaac tgcatttatt tatgcatttt
     6961 tctccaatca ttatatatgc tgtggtagga ggtatatcgc tttttttgtt taatatccca
     7021 agttctattg ctgtcccaac tgatagtcta atcataaaac gcaacactcc ttacactcat
     7081 ttattgtcat attcatttct atagccttat tctttgcaga ccttgatggt aatactattc
     7141 tattgactcc acacattata gataattggt ctagctcttt tctatacact cctcttggtc
     7201 tcatacaacc tagattaatt tcagtatctg gtaaattaat tctagcttca cataaaatat
     7261 ctgctacccc ttctaactca ggaggttcta cattttcata ctcagtccct tttgttggaa
     7321 taaggactat aaatgtaagc ttattaggag gatttttttg taggtattct ataatttcat
     7381 attcaccctt tatttgtcct ccttttaaac caatacatat atgtggtgct acttctgtat
     7441 gttcttgtat tgtattatag acttcaatat aatcttcttt actctttttc atcttataaa
     7501 cttctcttat tgtctcatca tcaaacacta aatcaaaaga aactatatct aaatacttac
     7561 acaactctac aatgctatct ttatccataa gacctaaatg agcattcaat ctatatcctt
     7621 gctcttttaa gtttttaatg gtattaatat gagtatttat agggacatct ccctcataac
     7681 tacaaccgcc actcaataga aagctagtta tattccttga ttgtactttt tcctcatatt
     7741 cttctattgg caccatattg tttaagtagt gaccgttgca atgggcacat ttcaaactac
     7801 attgattgct tgtagtacta agagctagtg tctggttagg ataagcaaac tctattttat
     7861 ttccaaaatt ctttaattta atatcaaatg ctattttcat tttttcagat agattcttat
     7921 tcatagttta ttccttctta agtacatttt actcttctag taatttcttt gctgttggga
     7981 actgctctat attcgtatgt ggtaagaaac atgcagaaat aaattcatcc atataacttg
     8041 gatatacact aagttcaaca taagttattt gattacctat ttcttcaagt ttattttttg
     8101 catctttact tataagagct aagtaagaac caacaagtga actattccct atataagtaa
     8161 atttttctct atcaatatca ggaagtaacc ctataattat tgagttttct atgtctaggt
     8221 tgtttcctat accacctgct atataaaccc tatctaatat actaaaatcc atacctaaac
     8281 tatctacaag agtgtatgcg cctgaatata tagctccttt agctcttatg aaattatcta
     8341 tatcaacttc attgactact atatcatttt ctaaatcaaa ttcttcttta aatgctaata
     8401 catactctcc tatctcatgc tcattaaatc taactctctt attatctaaa tccctgtata
     8461 ttttacctct tctatctatt acacctttgg taatcatttg acagattaaa tcaattatac
     8521 cagaaccaca tataccaact ggtgcacatt catcaataat ctttaatgtt ggctctaaag
     8581 tatctttatc aataattact ttctctattg ctcctgctga tgctctcatt ccacagctta
     8641 tccctccacc ttcaaaagca ggtcctgctg aacatgcaca gctcatcata taatctttat
     8701 ttccaaatac aatctctcca ttagttccta aatctataaa taaaacattt tcttcacttg
     8761 accatatccc tgctgataat actcctgctg ttatatctcc tcctacataa cttgcaacag
     8821 atggagctaa gtacacatat gcactgtcat ttacaaaaag accaacattt tcacccataa
     8881 gttttggaga ttttaaaaat ggtggtatgt aaggttcttg tcttaagaag tctgtataca
     8941 cacccaagaa taaacttgtc atagttgtat tcccagcagc cactaatgta actacatctt
     9001 ccttatctat tccatttctt tcatatattg tttttaatag tggatttata gtttcctcaa
     9061 ctatagcttt atgaagtgtc tctaatccat ttttcttagt tgaatatata attctattta
     9121 taacatctgc tccatatttt atctgtgcat ttccagaaga tgctttatct actacctctt
     9181 ttgagtatag gtctactaaa caaacaacta ctgaagttgt accaatatct attgcaactc
     9241 cgtataagga attttcttta tttccttgtt ctatatttat gattgtaagt ttcttttgtt
     9301 tttgaacata tgttattgta accttaaaat cactctttct aaatacagtt ggcatttttc
     9361 taagtatatc caatctaaaa tctatttcat tatatcctag gttatttcta acatatcttt
     9421 ccaatctatc tacatcactt atattatcat ctaaatttgg ttcttccatt tctatgtatt
     9481 tcttttttat atttgtttta aattgaaggt tatgttcttc aattattttt ttagctcttt
     9541 caaaaatttc cctatcctct tttttattac taccttctat cttcatacca tgcatagagg
     9601 atgatacttt agaaggaact tcaatttcta tatctgatat tacctttgta caacaagcta
     9661 gtatataacc ttgctcccac tcatcatctg ttatatgtct tgttttttct gtatcaactt
     9721 ttccattcaa taattttact ttacacttcc cacaagacac gtttccatta caaggagcat
     9781 ctatgaatat atctgcattt cttgcaacct ctagtaatat atccccctca ttacaataaa
     9841 cctctttatt gtttggtgta aaacttactt ttatcatgtt atccctccca atttgttcta
     9901 tatatgataa aaggaaagta tagctaaatt tgcgtgcact caaattttac tatactttcc
     9961 ccaattataa taatatctta atctttaatt attctaatcc agcctcgtat tctttatcac
    10021 ttaataacgt atcaagttca gccacatcag ctagttttac ttttaatatc cagttttcat
    10081 atgggtcttc atttatacat tctggctcat cttctaattt ttcattaact tccaatacct
    10141 caccattaac aggagatatt aaatcagaag ctactttaga agactcaact actccaaaat
    10201 ctactccctt agttacagta tcttctactt ctggtgtttc aacaaacaat atttctccta
    10261 attgatcttg agcatagtct gttataccta tatatacaac atctccatca attactttta
    10321 cccactcatg atctttagag tattttaatt ctggtaataa tttcatttcg atagaccccc
    10381 aatattatat tattgattaa attacttaaa tcatattaat attatatcat attattttaa
    10441 attttccatc aattacatta cactttccat agctaatgct ggatgacctt tttcttctaa
    10501 gaaagctaat actccttcag aatcgtcagc tatagtttca tcacaaacca tatcacagaa
    10561 gttttctatt ccagtcattt ctttaactgt agcatttaat ttatcagcta cataatcttt
    10621 taattctttt ggcatccaaa ctattctttc tggtccacct tctgcataag cgaatttttt
    10681 agaagatatg aaatgtcttc cgtgtcccat aaatcctgga gtttgaactc ctccacctgt
    10741 catagaagca agttctccga aagtcatacc aactggagta acacttgcaa attctctgtt
    10801 aactacaaca aatccatttg cttctggcat tataccacag atacattcga agcatccaca
    10861 agaagtcatt gggtcttcta gtatagagta taatgtaaca gattcaactg caccttgaga
    10921 tatttggttt acagtttcat ttactgaatt ccatacacct gttctatcat ctaagcactc
    10981 gcctttttct attggttgac aaggacctgt tgggtctagt tctttagtag ccttagcatc
    11041 taaccagcta actgctccac aaagaccaag tctttcagga gtaacaacac aaacgtgagc
    11101 tggtgcaaat gattgacata agttacaaga atagaaagtg tcaacacttt catcaactaa
    11161 tgaagctaat ctttcatctc tagcattgta cttagctatt gcttcacctt ttaattcaga
    11221 aactttttca gcatctgtaa ttatagttat ttcacactta tcaactactg attcaaattc
    11281 atctaacatc ttagcatata aaacttctcc tatatgctca agtctaaatc ctttatcaaa
    11341 tgcatcttta gagattctta cccaagccat atctctttgt ccaacgtgca ttacaccttc
    11401 tatatagttt aagaagtagt ggaaacgtct ttcaagaact ggctcgaaat cttcttgcat
    11461 atttttacca gctattttaa ctattacagc aagtggtaat cttaatacac catctgcatc
    11521 aacttcatct atatttggtc ctattatttc tatcttatgg tcttcaactt ctgttgcttc
    11581 tttcttaaca acaagctccc aagcttcagt tctgtttcca ccaaactcag caaacatatc
    11641 gctctttcta attctctcac cttcaaatgc tgctgcaaat gaaactggga taggtatttc
    11701 agtaactttt atttttattc ctctagcttc taatgaagta gctactatct tatcgtaatc
    11761 tttttgagtt aataggttca ttggaacttc aagaactgtt tggtcagtta taactgggaa
    11821 tcctaaagct attgctccag cacctgcaga tacaactaat tcacttaatg gtccaaatgc
    11881 attaacaaat gcaggaactc tattagctgt gtactctaat aatccgttta aatcaccagg
    11941 agttaatcca ccgaatatta atgctgctct tactgcaaca gatacaacgt gtataacaga
    12001 agttacatca tatcctagag gtataactct tagctcaaga cccattttta ctccagcttc
    12061 tatagcttgg tctatgactt taccaactaa gaaagttagt aaacctttag attggtaatc
    12121 ttttataact tttgctgctg attctgcatc tggacactca ccaagaacaa ctgcaacacc
    12181 aggtatatct cctgtaacta atggtacacc aagtgatctg attatagggt cagttatatg
    12241 acctgcacat ggctcactat atggagcatc catagttgaa tattttaatg cttcaattac
    12301 ttctgctgct aaagctgtag ctaaaccagc attaaaagca tgttctagta aatgagttct
    12361 atttattaaa gattttacta cttctaaagc accttctaag tcccctaaag tgttcatctt
    12421 ttgtcctgtt gcagcatata tacaaggtaa tgaatatgct gtatcaggga aagcaacttt
    12481 atgctctttt ccattctttt ctatagcttc agctaacata gcttgagccg cacctaaagc
    12541 ttgttctgac cctgtaaaga ttatattata tagattcatt ctatttcccc ctttaatatt
    12601 tacacctatt ttttattaac tataccctaa aaaccctaga aagcaaatcc accttcattt
    12661 aactctaaga aagagtctgc atataaagat gccccgttga ttatgtcaca agattttaca
    12721 gttttcatta attctgggtc acatggattc attatagctg aactaaatcc attagccatt
    12781 gccattgcta agaatgcact atctaaaaca ggtctaacat gcttaggaca tccattagat
    12841 acgttagata atcctcctgt agttaaaagt cccatctcag tcatcatttt tatagcttct
    12901 aaaacttcta cttgtttttc ttgcatacct tttataacta agcataatgg gtcaaatagt
    12961 atatcagttg gctccattcc taacattaag cctttttcta atatttcttg gcagtaagcc
    13021 atacgctcat cattatctct tgggatacct tcttttgcac ataaacctat aaccattgct
    13081 tcgtattcag ctgctatatc tattaaatca aatcttgagc cagcatcagc agagtttatt
    13141 attggttttg cattagttct atcataaact ttaagtccag cttcgatagc ttttttatta
    13201 gctgtatcta atgctatagg aacattgttg aactcagatt gaagtaattt gattccccat
    13261 gtcattattt cttcgccatc tctttcggca ggtcctatat taaaatctat atagtgtgct
    13321 cctgcttcta attgctcttt tgctcttttt aagattggag ctgggtctct ttctgctaat
    13381 gcttttctta ttgaaggtga tatacaatgt attctctcac ctataatcat aaatttttcc
    13441 atttataatg tcccccttta aatttaatat taatagttag ttaatatttt attagtttgt
    13501 ttggcatgct ttttcttggt atccttttaa gaacttaggt aattccatag attcctctgg
    13561 tcctataact acattccatc ctggtaagtt atcttctata tcacctttaa gtactgcaac
    13621 ttttcctgga atgataaggt ctttacaatt agttacttct tctaccttac tttctttaat
    13681 gaaagcagag attgagtttc caccaaattt accagcagcc caagatgtaa gaactgaata
    13741 tccacctgca tctggtatta ctaaccatac tggaactttt gatctttcta tatcaccagc
    13801 aactatgaag taagttaatg caaagtcaac agtaactaat actggagaat tttcatctgg
    13861 gttgttgatt ggataaatct ttggttcaac tctcattggt ctttgtgggt cagtgtatat
    13921 gttttgtctt agtgcaaata atggtaatgc cttagcataa ctaatatcat ctattactat
    13981 tatagaaccg tattttatag tgaatattga tgataaagca acttccatca tagggtttga
    14041 attagataat ctatttgcaa atactattga aggatatcca aatgttctat cttgctcttt
    14101 taaagctgtt cttctaactt gtatagcatt agtgtaagta tcttttatgt tttctcctgt
    14161 tacatctaat actaattctt tatatccagc agcttgaatt aattcaactg tttcatataa
    14221 ttcttctaag ctaccagctt ttacacctaa tggtaaactt gctcctttaa ctacttctat
    14281 catatctttg tagttctctt tagttgctcc atataccatt ggtctagcat cttttaatac
    14341 ttcaacagct tctttaacta cttgtgcatc atcacaagct aaaatataag ctacttctaa
    14401 tccactgcct tttattttat ctattaattt taaatacgca tctttatctc cacaatactc
    14461 taaaacagcc atttcaactt tcatttgttc accaattctt acatagtcaa cttttttcat
    14521 gttagctatt ttagcatcta ctgcttcatc actcatacaa gtacagaatg aaactgcata
    14581 tctatttcta cttactaatg ttttttcatg tctaaataat actgtttctc cacctagttc
    14641 atactcagat gcaccagcac caacttttaa agctttcatt aaaggtgcag tagcctctga
    14701 taattttgct atagcgtcat cagacatatg tgggcattta cctacttcta cagctcctga
    14761 agcaaccttc atagagaaag ccatacaagt tgggaatcca caatccttac agtttttctt
    14821 tggtgttaat ttaaatatat ctaaagcttt taatgccatt attttttccc cctaacctta
    14881 acaatttaat taagctaatg cgttaaccaa ttcttttata gtttctattg attttggatg
    14941 acgaagtata actgcgtttg aaccacctac taaaacactt gctgcagttg aaacttccat
    15001 tgctatagtt ctttcttctg gacaacccca atctggctca tcttctattg gagctatagc
    15061 ttctttaaca tgacctactt caaaagctac tggtgttatg ataggcattt gtaatgtctt
    15121 atcattttga ccaaatgctg caagtctaat tctatccata gtagatgcaa cgtactcata
    15181 tccataacca actgctgaac atccaacatt cataactata ttttcacctt taacgcctag
    15241 ttgagttaac aatacgttta attgtttagc taggtttata tcaacagaag attcagctcc
    15301 tactttatgt gcataagcca taccagctga tgctcctact cctttgtagt tatcttctac
    15361 tgctgacata aataagcagt tatgtccatc caatgtttga gctaattttt caaataattt
    15421 accatctttt tcatgatttc ctgaaccagc tacaactaaa ggtaatttta ttgcttcaat
    15481 tactgcctta gctacatcag cacattcatc aactgactta tctaatccat ttgggtcaga
    15541 accatcaaat tttaaacaaa taaaatctgc ttgtgtatta gcttcaacat atttagccca
    15601 ctctactgga caattagcta catctttgta taattcctta tatgaatcag tccagctttc
    15661 aggataaacg tctgatattt gtatccctat ttttggagaa ttacctactt ctccatcaaa
    15721 actataaaaa ggtaatacat tttccccacc taatttaatt gctttttccc ctattcctac
    15781 ttcaacttct gatatttttc cagaatattt ttgagtagac attttaaatg ccatattttt
    15841 ttccccctta agcctatttt aattctaatt tagcaaaaat ttctttcata gccactttag
    15901 attttgaatc ttcaggtaaa ttaactaaag gaatacctgt agaatcatat tcatatatca
    15961 attcatccat aggtacaaca ccgattagct ctaggttatg cttttcaatt tcttctttaa
    16021 caccatcatt cataacccca tttggaactt tatttacaat caaaagtatt cttccaacac
    16081 ttaactttag ttcctcagct aaatctctta ttctagcaac agcttgtatg ctacgtcttg
    16141 agcaatcact aaccaataaa agtgtatcaa catgtctagt gacttttcta cttagatgtt
    16201 ccataccagc ttcgttgtcc atgactaagt atttgtaatg accagatatt ttgtttactt
    16261 gttctctaag tatcccattt acaaaacagt aacatccttc accttctgac ctacccatta
    16321 ctaataagtc atatccttcg ccttcttcaa ttatagaatt taatctaaat tgaagatatt
    16381 gtgcctttgt cataccacca gggaatgcat tgcctaactt ttctctttga tttacttctt
    16441 ctcttatttc tcctattgtt gcttcaactt cgatacctaa tacttcattt atgttagcat
    16501 tggcatcagc atctacaact aatactggtc cctttttgtc cttaaccaaa taatcaatca
    16561 aaagccctgt gagacttgtt ttaccagttc caccttttcc tgcaacagct atattgtatc
    16621 ccattttaag acttccccct taaatctagc cacagagcct tatgtactct gtctgtctat
    16681 tataatttag gtacagaatg aacacattct ccatgtacat catgaagtgc ttccattagc
    16741 ccttcagata aactcggatg tggatgtatt gcatccccta cttgttctac tgttaatcct
    16801 agatgaacag caagtgacaa ctctgtcaat aaatctgtag catgaggtcc tactactgct
    16861 gcacctatta tcttatcagt ttctttgtca gctataactt ttacaaatcc ttggaaatgt
    16921 cctatagctt gtgcttttcc aagccctcta aaatcaaatt gacctacatt gtattctaca
    16981 ccttcagctt caagttgctt ctcagtctta ccaacaccag caacttcagg ttcagtataa
    17041 acacatcttg gaattgctct ataatctact accttagtct tacctaaagc attttcaact
    17101 gctacgatac cttctttaga agcaacatgt gctaggaaag gagtatctat tatatcgcct
    17161 attgcgtata taccttctac attagtttca agatgttcat taactactac ttttcctctt
    17221 tccatttcaa ttcctatatc ttctactcca gaattgtcaa ggttaggtct tctaccaaca
    17281 catactaatg catattgtgc ttctataacc tttccattag aaagagttgc aacagcctta
    17341 ccatcaacta cttcacaagt ttgtactcca atacctgtaa taaccttaat tttatctttc
    17401 ttaaattgtc taagtagttg tttagctaca tctttgtctt catttaatag tatttggtca
    17461 accatctcaa ctatagttac ttctgttcct aaggctctaa agaactgccc tatctcacat
    17521 cctataactc caccacctac tattaacata gactcaggta tctcttcaag tccaagaact
    17581 tcatcactag ttattacaac ttttccatca tatgggaaca ttcttggtac aactggaaca
    17641 gaaccatttg ctagtattat cttatctgct tttatagttt ctactgttcc atcatcttta
    17701 gttacttcta tagtgttttt atcaattaat tttccaaaac cattaactaa gtttactcct
    17761 cttttttcaa ataagaactc tataccactt attaattggt ttacaacttt attttttctt
    17821 tccattatgg cagtgaagtt tggcttaact gtaccatcta tttctatacc aaaatccttt
    17881 gcttctttta cagtattcaa tactcctgaa gaagcaagaa gtgctttagt tggtatacat
    17941 cctgcattta agcaagttcc tccaactctt cttttttcaa caactgttac atctgcacca
    18001 agcatagaag cttttatagc tgctacatat cctcctggtc caccacctac tactactatc
    18061 ttcatcttta attcccccaa acctaatata atctacaatc ttgcaatact ataaacctgc
    18121 ggcatccagt atagcaggta tattctcttc tgccccaatt gccattatat gaacaccatc
    18181 acataaatct tcttctttta attgtttgat aagttcccct gccattttta ttccttcact
    18241 tacccagttt tcttttccag ctgctcttaa tctttcgatt tgttcatctg gaacaaatat
    18301 tcctggtaca tttgcagtca taaatttagc cattcctggt gattttaaag gtactattcc
    18361 tgctaatacc ttgcaatcca tattccttgt taattctcta aactttctca ttgtatttat
    18421 gtcataaagt gcttgtgttt ggaaaaattt agcccctgct tttattttct ttttcatttt
    18481 taataattga acttctattg gagaatattc tggagttact gatgctccta gataaaaatc
    18541 tggagaacct tttaacttat taccagccat gtccgtacct gccattaaag tctcagcagt
    18601 ttgaagtatc cccacagaat ctaaatcaaa cactccctta gcttgtggat ggtctcctac
    18661 gctagtatgg tctcctgtta gtgccaacag attgtttatc ccaaatacac ctgctgacaa
    18721 catttctcct tgtatagcta ttctatttct atctctccct gttatttgaa taactggctc
    18781 taatccagca tcttttaata atttacatgt agcaagagaa gttgctctca taactgccga
    18841 ttgaaagtct gttacatttg ctgcatgaac tcttccaact aacggctttg cacattctat
    18901 taaatgtgaa aggtcagtcc cttttggagg agccatttca gtagtaactg caaattttcc
    18961 actttctaat gtttctctta ataagctcat ctctaatccc ccttttaacc ttctaaaaaa
    19021 aacttttatg aatttgctgc tgcttctttc tttttctttg cacttaaact tcttggatta
    19081 ttttgcttag aatagtcttt tggtggtctt atttctgcta agttatctaa ttgtcctata
    19141 gcttctagtc tttcatatat ctttatccaa gcacaatcat tctctgagtt tacttcacac
    19201 ttaccatttt tagctccacc acaagcccca ttcataagac ctttagcaca catagttact
    19261 ggacatatcc cacctgtcca accaagttca cagtctccac aagccttaca ggcttcttca
    19321 tattctccaa ctctttgtac ttcccctata aacaaagtat tgttggctgg ataaactggc
    19381 ttatctttta aattcttaac tattgtctgt gtaccatctc cacatgctaa agataaaact
    19441 gcatcagctt ccttagtctc ttcttttaga gcctttaaat cctttttaga ctttaaaagg
    19501 ttacaagcag ggtcaagcat tacatatcct aagatttttt tgccttcacc ttcaagagtt
    19561 tccttcattt ttaaaacttc ttcttcccca ccacttttac aagttgctgc acattgatta
    19621 caaccaacta aaaccagctt gtcaaaatct tttaagtacc ctagcacttc ttctaatggt
    19681 ttattttcag aaattatcat atctacttcc cccctaaacc ttccacatat atatatctat
    19741 ttattgtttt gtaatttaca agccttaact acatgttttg caagtataga tgttgtaact
    19801 gaaccaaccc ccgctggaac tggagttatc attgatactt tgtctaaaac tgcatttgta
    19861 tcaacatctc cacataaatt tccttcttca tcaacattta taccaacgtc tataactacc
    19921 gctccatctt taacaaaact ttcatcaacc atcttagctc taccaatagc tgctattagc
    19981 acgtctgcct ctgctgctac acctgataga tttttagttt ttgaatgaca tattgtaaca
    20041 gttgcgtgtt cacttaataa aagcattgat actggctttc caactaccat tgatcttcca
    20101 agaactgtta ccttacttcc ttttaaatca acattatagt gttttaatat ctcaactact
    20161 gctgtaggtg tacatggtgg aaatccactt ttatcccctt ccattacctt agcagagttt
    20221 attggactaa aacaatctac gtctttttcc ggtgcaataa catattttat aacttcttca
    20281 tttaagtgtt ttggaagagg tctaaaacat aatataccat taacattttt gtcatcatta
    20341 actctcttta atacatcaat atattcctct tgtgttatat cctcagctaa ctctaacact
    20401 tctgttgtta tacctatgtt ttgacatctc tttagtgctc ctctttcata agataaatca
    20461 tcacttcttg ccccaactct aactattgtt agtttaggat ttataccttc tttaattagt
    20521 aaatcgactt cttttattaa ttcttcacta atcttatcag ctacaggttt tccttttata
    20581 atttgtcctt tagttgacat tccttccata cattcacaac tcccctacaa gcaaacttaa
    20641 attaatttat tctatatacc acatattaat aacatagtat ctactttcgt catttaaaaa
    20701 ttattttcca agagcttttt caactttggc ataaacttca tcacaaattt ttacaccatc
    20761 ttcaactaac ttatctactt ctgtttttac cttattaaca tattctttat cttgtataga
    20821 atttatattt ataactacat ttaattgtcc accaagtata gcagctctta aacactgaac
    20881 tcctacacca acatcactta tagcaagtct tgaaccttta tcaactaaat cttcatgtaa
    20941 cttaatagct tcatagcaaa ctcttactat gtttaatggt acttcacaag caacttttaa
    21001 tgccttttcc attgtttctg cttttattct tttttcttct tctgtttctt taggaagccc
    21061 gtaagctttt gataatggta agaaacattc tgcatcatca tctatcattt ttaataaatc
    21121 tttttctaac tttcctgcct tacttaatat ctcttttaca ctttcttcat actcagcata
    21181 cttcttcttc cctattgtaa ggttacatac catactacct aaagccatac ctattgcacc
    21241 tactagtgca gcagctcccc caccacctgg tactgcttct ttggaagata gtacttctac
    21301 aaaatcaaca caagttttat ctgctatttt catgataatc ctccttgaaa ggatgtagga
    21361 aaatatctca aattgttcga gatattttac gaactatttt aagatatctc ctactcttta
    21421 tttataaatt aatttcctta gaataatcca gctattactc cattttcatc aacatctatt
    21481 ttttctgctg ctggaacttt tggtaatcct ggcatcttca ttatttctcc agtaagtgca
    21541 actataaatc cagctcctgc tgaaattgtt gcttgtctta cagttattct aaatcctgtt
    21601 ggtctaccta atttagtttg gtcatcagtt aaagaatatt gagtcttagc catacatact
    21661 ggaactttag taaatccaag tttttctaag ttagctattt ccttatcagc ttcaggagta
    21721 taatctacac catctgctcc ataaatctta gtagctatag catttatctt gtcttttata
    21781 gataaatcat cttcatagca gaatctaaag ttattttctt cttcatccaa taatcttaaa
    21841 acttctttag ctactgcaat tccaccttct ccaccttttg cccatacttc agaaagagca
    21901 acattaacac ctaattcctt acacttgtct tcaacaagtt taagttcagc ttcagtatca
    21961 agtgggaatc tgttgattgc aacaactgct ggtaatccat atacttgagt tatgttttca
    22021 acatgtttta ataagtttgg aagtcctttt tcaagagctt ctaggttttc gttatttaag
    22081 tctgctttag caactccacc attgtatttt aatgctctta cagtagcaac tattataaca
    22141 gcatctggtt ttaagtttgc cattctacat tttatatcta agaatttttc tgctccaagg
    22201 tcagcaccga aaccagcctc agttattaca taatctgcaa agtgcatagc cattcttgta
    22261 gctataacag agttacatcc atgagctata tttgcgaatg gtccaccgtg tacaaatgat
    22321 ggtgttcctt caagagtttg aactaggttt ggttttaaag catcttttaa taatgcagcc
    22381 atagcaccat tagcttttaa ttgtctagct gttacaggtt caccttcgta gctgtatcca
    22441 actattatgt ttcctaatct ttcttttaaa tcagatatat cacttgccaa acagaacgct
    22501 gccattattt cagaagcaac agttatatcg aatccatctt gtctaactgc tccatcacct
    22561 tttttaccca taccatcaac gatatttcta agttgtctat cgttcatgtc tacacatctt
    22621 ctccaagtta ttttcttagg gtctattcta agtgcatttc cttggtgaat atggttatca
    22681 agcatagcag ctaaaagatt gttagcagct cctatagcgt gaaaatctcc tgtgaagtgt
    22741 aagtttatat cttccatagg aacaacttgt gcatatcctc caccagctgc tccaccttta
    22801 acaccaaata ctggtcctag agatggttct cttaaagcaa ctaatacatt tttgtctagt
    22861 ttagcaaatg catcagcaac acctatagta gtagtagttt ttccttcacc tgctggagtt
    22921 gggtttatag ctgtagttag tattaactta gcttttttac cagtctctct ttttagtaga
    22981 ttgtagtcaa cttttgcttt gtatttacca taaagttcta catcatcttc acctagtcct
    23041 aatttttttg caacctctct aatatcttga ggcttagctt cttgagctat ttcaatgtca
    23101 gatttaaatc ccataactga atctcctccc acaacctaaa tagatttaaa atataatttt
    23161 tgtaaaaatt gtattaatat gtaaaaatta tattttataa gataattata catgtaaaat
    23221 tacttaaaaa ctagctacta agctattaaa atattcaaac ttaatagcta gttatttatc
    23281 taattactta cttattacct atctattgcc tatgtctaac ctttaaccaa cttaaaatcc
    23341 caaatcaaaa tttctatcta ttttatttat ccttaagtga cattaattta tcttttattg
    23401 ctttaatctg ttctttcgtt gtttcactag aatcatatgg agattgatta gctctatcag
    23461 aatcaataac atcttggtta taataaataa atcctaaaga ttctccatct tctaagtttt
    23521 ggattataaa ttcttcatct tccttatttc taattttatt tcctactaca aatactttat
    23581 ttacacctat atcatgtcca agtttcttaa cttttctata agtctgtaga cttctctctc
    23641 ctggttctac aactactata aaagcatcta caccttgggc tgttcctctt cctaagtgtt
    23701 caattcccgc ttccatatcc ataaccacta catctttatt ttgtagtatt aaatgtgagc
    23761 agagtctctt caaaagaaca tgctctggac atacacatcc agtaccacca gaatctacgg
    23821 ttcccaatgt aagtaatctt actccattgt attctttaca gaaattttca gggatatcgt
    23881 ctactttagg attcatctta aacatttttc caaatgaacc tacagaagca gctgttctat
    23941 ctgaaactaa ttttttcatt tctgatatag gtactattga ttcatatact tcttttggaa
    24001 aacctagtgc taaagctaaa ttagcatcag ggtcggcatc aacagcaaca actctgtatc
    24061 cgtcttcagc aaacatccta gagagcattg aagaaaaagt cgttttacct actccacctt
    24121 tacctgttat tgctatcttc ataatcccta ccacctttta ttactatttg ctttttagta
    24181 gttaatttta cagttaaata ttttttatac tctatatttt tatacactaa aaataaacta
    24241 cagctagtcc ttacaggaac caattaaatt taccctacta gcttttcaaa gcagcatgta
    24301 tagttttatt attctttaat attgtttata ttttatttat tcagtatatt cattatattt
    24361 tgatgttctt tactttaata tttgacttta ttcaacttta ttcaaccaga aacttcttat
    24421 aaaaacgttt attctataac ttcactattt tttaagcttc agccttttct gccatctttt
    24481 cttcaactaa tgcttcaaag tgaacacgtt ttttctctat atcttctatt attgtagctg
    24541 ctaactcttt tggatttgta tttacagtaa atgtagctcc aactttatct tttaattcac
    24601 tagttaatat atccactgct cttgaagaac cagctattgg aggcattatt cctaaataag
    24661 tgtctatacc agaagctaca acatagcatc ctatagcaac tgctttttct gacatccact
    24721 ctggagctat acctacaact ggaaggtcac acatatccat atctaagtaa ttagctgctg
    24781 ctccaactaa atctagtata cgacttatat caacacaaga acccatatgt agtactggtg
    24841 ggattcctac taatttacag acagttgcaa gacctttacc tgcatatttt tcagccgcat
    24901 cagattccat taaaccaaac ttagctgctg ctgaagctcc acaacctgta gtaactacta
    24961 ttatgtcgtt tttgattaat tctttcatta ttgttacgtg agcctcattt gaaactcctt
    25021 tagcattgtt acatccaact acaccagctg ctcctcttaa tactccagct tttagacagt
    25081 ctgttaatgg cttaactgtt cctgctgggt ctatatgaga gtttacaact ctgtctaatt
    25141 gatttactac tgcttctaca ctatacccaa ctgttgcccc tgattttaat tcaggtataa
    25201 gtacttttga tttatctcta tttttaaagt ttaaaatagc ttctttaact attgctttag
    25261 catcatcaag tgcttgttct tctctaaatt caatataagt tgaacctgtt atcttagctt
    25321 ttggagaagt tgttacaaat ttagtatggt agcaatctgc aactctagct aatgcaggga
    25381 atatacattg aacgtcaact attacagctt caactgctcc agttattatt gcaagttctt
    25441 gttgatggaa gtctcctgct atttttacac catgtctcat tgtaatctca ttacctgtac
    25501 aacacatacc tgctaagttt attccatcag caccaacttc tttagctaaa gctactaagt
    25561 ctggctcttc tgatgctaaa actatcattt ctgataatgc tggctcatgt ccatgtaata
    25621 ttatgttaac tttattttct tctaatactg ctaaattcgc ctctgttctt cttggcactg
    25681 gagttccaaa taagatatcg cttagacgag tacctatcat agaaccaccc caaccatcag
    25741 ccatagaagt tctaagactc atgtgtatta aactatctat atcaccagta catcctatat
    25801 gagtagagtg cattattgtt gcaatttctc tatctatagc tcttggctct atagcgtatt
    25861 ctttccatat tttttgtctt ggttctggtg cattttttat aaatcttaat gtcccaaaag
    25921 gttttccaaa ttccattaat gcaatttctg ccacttcatg tgctacatca tagatatctc
    25981 taccttctgt ctctacatcc cattctttag ctaaagtaat taacttagct tcgtctctta
    26041 ttttatagtt tccatttgga tcagctaatg ctaatgtatg tgctatatct ctagcatggt
    26101 ctgaatgggc agctgtccca ccagcaacca ttcttgcaaa gtttctacct actatagtat
    26161 gctcatctgc tccacataac ccccttggag tcttagggct tattctacat ggtcccattc
    26221 cacatattct acagcaaaca ccttgaagac caaaaccaca ttgtgcctta aagccttctt
    26281 ttctatcata cattgtttct acgccttctt ctctagcttt agctatcatc ttctggctgt
    26341 ttaaatcaat tgttaacatt ttttcatcca tattcctatc cccttttttt gatttttaaa
    26401 atcccccagg tgactgactt catgtcataa aataataaaa taaatgcttt ctaagttgat
    26461 tatatactaa ttttcagtgc tttgctttag atttaaatat ttttttaaca aaattagata
    26521 atacataaaa attttatttt ctacacttaa tttaagttga ttttatcgct tgtttttggc
    26581 tatttgttaa tatctaaacc tacttttttg atacttcagt ttaattaaat tatgttttga
    26641 tttttttaaa tcaaatttga aatttttcta gtcattttta tattattgca gattgtttgt
    26701 gtatttatta tctttcacta ctgtttggac ttattacaga tttttactcc ctaaacttaa
    26761 ttagtaaaaa cttcttagaa tagcattttt tggactaatt tttttgaatt tttttatttt
    26821 tcctacttta atattaatta tagcttcaaa ttgaacattt gtatatattc atttgaagct
    26881 ataattattt tttatataaa acttttttaa tacagcatta atttagacat tttgactatt
    26941 ttttctactt taattcattt atttcaagcg atttatccta tttcatattt ttagctacaa
    27001 tagccccata tgcaatagaa tataatttag attcatgtga atcagctctt gacactaaaa
    27061 ctataggagc ttttgcaccc ataattatac ctgctgattt agagtctgcc atatatgtaa
    27121 aggctttccc tattccatta ccaacctcta ttgttggaac caatatgata tctacatctc
    27181 cagatacttc acttttaaac ccttttatct cactagcttc ttttgaaaca gctaaatcaa
    27241 aagccagagg accttctaca attacatttt caccaaattc tccttcttta caagcttttg
    27301 ctaacatatc tgcatctaca gttgcttgca tcttaggatt tactttctct ttagctgcca
    27361 aacatgcaac ttttacagtt tccattccta aagcttttgc agcttttata gaatttttta
    27421 atatctttgc cttttgttca taatcaggag ctatattcat acctccatct gtagttataa
    27481 gtaatttatg gtatttttct aactcatata ccataacatg acttaataaa ctatcagttc
    27541 taagaccata gtctttattt aacacttctt ttaatatgac agatgtatct aataatcctt
    27601 tcattacaaa gtcagcttct ttacttgata ctaatttaac tgctatttct gcacactctt
    27661 tgatatcatc cttatccact attttgatac cacttaaatc aaatcctatt tcttttgata
    27721 tttctcttat tttgccttca tttccaacca atataggagt aattatattt ctttctacag
    27781 catcctttat tgccattaaa acttctttat catgagctgc tgctacagag agtacaattt
    27841 tctctcctcc cttaagttgt tctaaaatat catctaattt ttttatcaaa agtaacccct
    27901 cccttatata tatttaacta aataatacca tatttgctat accttttctc aatttatttt
    27961 ttatgttata aagaatttat ataactaaaa gacagtttaa tattttattc tgggatttca
    28021 tcaataactc ttaaaagctt tgcaggaaca ccacctacaa tagtattttc tgcaacattt
    28081 tttgttacaa ctgctccagc agcgataatt gcattatctc caatagtaac tcctggaact
    28141 acagttacat tagcaccaat ccatacattt tttcctattg tgattggaga aggataagtt
    28201 gtaccacgtt tctctggtgc aataccatgg ttaagtgtag ccaataccac attatgccca
    28261 atttgcgtat tatctccaat ctcaatcccc ccctggtctt gaaaatggca actgctattt
    28321 ataaaaacat tttttcctat tgtgatgttt tttccacaat ctgtataaaa tggtggaaac
    28381 ataaaaaatg attcatctac cttttttcca attaactcag aaaataaact acggacttct
    28441 tctggttcat gataagaaga atttaactta cttgtgattt tcattgcttc attactcaac
    28501 ttaaccataa attcatgtat ttctgattta ctagaaacag gttttctttg attgatatgt
    28561 gttaaaaatt cattgatatt cattttatac atcctttcaa tatgtgcttt aatttatttg
    28621 tacattctaa ataatatttt aataaaaatt aatttaattt atttttatta aaatatcatt
    28681 gcttctttta gtgtaatata caattatatc tatatcaaat atctatatta aatacttaac
    28741 tatacttaaa aagcatttaa attgatataa ttatataata aataagttaa tattgaggag
    28801 agataattat ggaaataaga gtattaagat attttttagc aattgcaaga gaagaaagta
    28861 tatctggtgc ggcaaccttt ttacatataa cacaaccaac actttctaga caaattatgg
    28921 aacttgaaga agagttggga gttaaattat tggttcgagg aaatagaaaa atcaccttaa
    28981 caaatgaagg taggctttta cataaaagag cagaagaaat tatatcatta gttgataagg
    29041 ttgaattaga atttgacaat cccaatgaga ttattagtgg tgatatatat ataggaagtg
    29101 gtgaaactga agctatgcga cttatagcta gaactgccca tcattttcat caaaaatacc
    29161 ccaatgtaag atatcacctt tttagtggga atgctgatga tgtgactgaa aaattagaca
    29221 agggactgct tgattttggt attttaattg aacctgcaaa tatacagaag tatgattatg
    29281 cacaaattcc tgctactgat gtatggggtt tactaatgcg taaagatagt gcccttgcat
    29341 cacaaagcac aataaatcca aaagatttat gcaatatacc tcttattatt tcaagacaga
    29401 cacttgttga taaagcaatt tctaaatggc ttcaagacag taatgaaaaa ctaaacatta
    29461 ttgcaacata caatttagtt tataacgctt ctcttttggt agaagaaggt ctgggctacg
    29521 ctctgtgttt agatagactc gtcaatacta cagaaaacag taatctttgt tttagacctc
    29581 tatctcctcc tttagaagct aaattaaata ttatatggaa aaaacatcaa atattttcaa
    29641 aggcagcaga aaaattttta cttcaaatac aaaaagattt ttcttctatc atgttggata
    29701 catctaagtt ggatacacct aaagaaaaat aaatcataat aaaaagcgag agtgtctcaa
    29761 aatgaacttt gcactgtata aggcactctt ttttatacaa agtaaaatat atgttcatca
    29821 tttcagcact aaaaaagagg cttatctcta ttttgagata gccccactta accaataaaa
    29881 ttaaatacaa cttaacaata tccttactta tttattccaa gttctcttag acaagcaatc
    29941 gtaatttcat cttgtggatt taattcataa gctctttcta tatagtaagt tgcatcatca
    30001 atatcaccat tatttaaata agccattcct aaattgcaaa gtatttctgg gtcttccttt
    30061 atcttagccg cttgttcaaa atactctatt gctttatcta aattattctt ataagcctca
    30121 caaagcccca attccactat agtatccacc tgattaggct ttattatcaa tatcttctca
    30181 agatacatct tagcctgctc tatttcgccc atacccttat atccaagtgc tatcataaac
    30241 agcaagttcc accaatccat atgttcttct tctaatggaa gtaacttctc taatccttcc
    30301 ttaaacttac cttggaatac aagtgtatat ccttcttcat attgaacttt aaagtccatc
    30361 ttgcccagat tctcttgtac ctcagctact aaatcagcat ctaaccctag ctttaacgct
    30421 tcttcccaag tcagcttagt ctttaaatat tgaccttgat tataataatg gtagcctaag
    30481 tgataataac ctaatgcaaa attctcatca acatcaatta ccttttcaag cttagccatg
    30541 gcttcaagta agaatgcatt cattgcctta tcatccatat ctttttgata ctgtttagct
    30601 atctcttggc aaacaatcgc atagttatac attgcatcta aatcatctgg atacattgtt
    30661 ataaatgctt ttatatatat taaagaatct gtatgttcac caatctcaaa gtattttctc
    30721 gacatatatc ccatatacga tttcaaatcc aaatcaatat cttttgataa agcatttaaa
    30781 aacttctcat actctgcatt gtttttaaac ttactatcta ttccaattat atatatcatt
    30841 gcatctgcta tagacattga atttaactta tcttgagcag tcttttcttt tatccctttt
    30901 actaatacct cattttttat aggtacatct aatccacctt ttggcacttc atagcttttt
    30961 aatttaaact ctccaccatg ttttatagtt ataaaagcta attcttctgc tttttttagc
    31021 aaatattttt ctatcttaaa atccatttta tcctcctaaa tacttaaatc tctactttat
    31081 gagttttaga tttctcaaat atttttttat catcatactc aaataagact acattttcta
    31141 cttctcttat ttctgtattt atatcatttt ttaaatccac aacattaaat ctaaatggct
    31201 caaaatgaac atattttatt atatgtttag ctggtttatc aacaaaacta ggtaaatatg
    31261 ttgataagtt atcattatct tgtaaaaata catggcatct attcttaaaa tcatccacat
    31321 ctagcttatt aaaaaactgt ggtatatttg atgttttacc cagtgatata tagtcatatt
    31381 ttaatatatc gttgaataca tcattatcta tgttgatttt ttcattatag aaatccatca
    31441 atattttata taactgattc tttccttgtg ccaaatcaaa gtagccattt tcatcaaaat
    31501 acttggcaaa aacctcaaag aatttaaaag ggctttgttt ataaaatctg cctataatat
    31561 atctcataga taacacaaag tttttagaat tgtagtatct ctccagtata tcttctatat
    31621 cctttagctt caaagtttct tcatagctta tataattatt gtataaaaac tcatatggag
    31681 cataatcctt atatttaaaa ccatgctcat ctgcaacttt tctcatacct gtccctttaa
    31741 tcatctttaa aaagcctaat tgcaaatgct ctatacctag attaaataca tcattaaaag
    31801 aattttcaaa gctcttataa tcttcataag gcagtcctgc aattaagtct aagtgctgat
    31861 gtatatttct atatgatgct acagtttgta caacatgaga caacttttta aaatcatccc
    31921 ttctacctac tgcatcaagt gttttttcat tcgttgactg aacccctatt tcaaattgaa
    31981 aaagaccttc tttacaatca gccaaaaact caagcatctt atcatctatc aaatacgctg
    32041 taacttcaaa atgataagtt gtatatccat tatcattttt cataaggaaa tccatgattt
    32101 ccatagccac ttttctattt gcattgaatg tcctatctat aaactttatc tgtgatactc
    32161 ttgcatctat taaagctttt aaatcactct ttatcctgtc taaactaaaa taccttagac
    32221 ctggaatagt agatgataaa cagtattggc agttaaaagg gcaacctctt gatgattcat
    32281 aatacactat tctgttttca tattcttttg gattcaagtt ttcataagga ctaggaatct
    32341 catccaaatc ttgaagtaat tccataggct tattcactat tatctcattg ccttgtctat
    32401 atacaagtcc atttacatca tttatttcca tctttccttg caagtgaagt actaagtctc
    32461 taaaaattaa ttctccctct ccataaagta tataatccac aaaatcatac tttttcattg
    32521 cctcataact atcataactc acttccggtc cgcccaaagc tattttagta ttaggtctaa
    32581 ttttttttag attatcacaa agtttaacta tatctcccac attccagata tatgttgaga
    32641 ataatattat atcatattca tttttatata tatcctttaa aatatagtcc aaatcgttat
    32701 ttatcgtgta ttctttcata ttaacttcta tcaaatctct tacaaattct tttagatatc
    32761 ttatagccaa atttgtatga ataaacttgg aatttaatgt tgttaataaa attttcaaat
    32821 atttctcacc tctttttaag attatactgt ctttttgtac cccttatagg ttaaaatagt
    32881 atatgtaaag tctaaataat atctatataa ttaatttatt aatttcaagt aatgtgagga
    32941 aaggaagttt tttatggaat taattgaaaa agtatctatc aactctttat caaaaagaga
    33001 tttactactt attataaagt ctcttgaata cactaatgaa aatactcaaa ttagtgattt
    33061 cattgacctt aggaataata tagtaaagga attatgtttt ttaactgaca ctaaggaaaa
    33121 agatttttta gattatctag aaaaaaatag cacactctaa taacctaaac ctttttaaac
    33181 tttaatatat aaatacctga tttagaattt atttttatgc ttaatatatt atcattaaag
    33241 gttttcgaca taactgttat ttgattaaat atagggtcta ctatagtatt accttcttca
    33301 agtcttataa gacttcttgg gtctatgctt ttattatatg ccttaactcc aattttatat
    33361 tttctcaatt taacaacata ttcggacata gaaaaaataa aatctatatt atcttcattt
    33421 aatttactat cttcacccaa aatggataat atagattttt ttatgctatt aattccttca
    33481 ttttctacag ttctatcttc catatataca tcatatagaa catttaaaac atttaataaa
    33541 atactttctt catcataatc ttcagatttc aaatcaatgt acttatcaat taattgtatt
    33601 gctttaatcc ttgccatctg aaattttaca acatctgatt tgtctaattc tatagaaaat
    33661 cctattatct tgtctttaat actctgtagt aattcgacat actctatttt actattattt
    33721 ataagattgt gcataatgga attatacact acagaaccta ataaataatc aaataaaagt
    33781 tcttcttttt taaaataaat aacatacttt tttattagtt taataacctc atcttcactt
    33841 ttttgaatat tagtatttga taaaattagt ggtaataaaa tatttaaaaa attgatattt
    33901 cctatttttt ctccatagaa tctatagtaa ataagttcat ctctcagtct attttcgtct
    33961 atatacacac atctttgcgt tttatcatct attaaggatt ttgtatttat tatagttaaa
    34021 tctttaagag ccctacttgc actactaaaa gaagatgtgt agactttttt tagtaattcg
    34081 tcattcataa atatatcctt tctgaaaaat tgaatgtaaa taaattgtta ttaaaaaaaa
    34141 agagacagcc cgtttaagaa gctgtcatat atagggggat agtagtgtac aaaaatcatt
    34201 gtaatctact atctatatat tattatacga tactactttt ttatatgtaa agcatcagtt
    34261 ttcgacatcc ctatatttta cagttataca aattgcgtac taagttcaat tttattcttt
    34321 ttatttcaac attttatcat gctacattct ttcaggagcg tgcattccca acaatttcag
    34381 agaattttct aaagtttgtt ttgttgctaa aactaatgca agtcttgctt ttcttatttc
    34441 caaattttct actaaaattg gattgtcatg ataaaattta ttaaacgctt gagctaaatc
    34501 tagcataaat ctagtcacta tatgtggctc atttttcttt agagcaagta aaatattctt
    34561 attgaatgat tctataactc taagaacttc tgcactatct tcatcagcta atagactata
    34621 atctatatca gaagtcactt ctacttctgc ttttcttaaa actgcacagc atctagcatg
    34681 tgtatactga acatatggtc cagtctcacc atcaaaacta agcgttcttt cccaagagaa
    34741 agtatagtct ttaattctac tattagataa ctcttggaat actactgccc caacacctac
    34801 ttgcttagat atttcatcca catttttagc atttgggttt ttagctagta taatttcctt
    34861 agttttatct atagcttgat ttaaagcatc ttctaaaaat actactcttc cttttctagt
    34921 cgacatagta ccttcttcaa gtgcaaccat accaaatcca acatgaatta aatcttttgc
    34981 ccaatcatat cccataagct caattacctt aaaccattgt tggaaatgta agttttgttg
    35041 agaaccaact acatatatac acttgtcaaa atcataagtt tcttttctat atattgcagc
    35101 agctaaatct cttgtcatat ataacgttga accatcattc ttagtaataa gtgctggtgg
    35161 cattttatac tcttctaaat caacaattct tgctccttta gactctttta aaagattttt
    35221 ctcttctaat agttcgataa ctctgttcat tttatcagaa taaaaactct ctcctgctaa
    35281 agaatcaaat tctatatcta aaagtttata cactctgtta aactctttta aactctcatt
    35341 tctaaaccat tgccataatt cttgtgcttc ttcgtcacca ttttctaatt tattaaacca
    35401 tgctcttgct tcatcttcca tttctgggtg ttgttcagct tcatcatgga atcttacgta
    35461 taattttagc aattctggaa ttggattaga ctctactact tctttttctc cccacttttt
    35521 aaaggccact attaacttac caaactgagt tccatagtca cctaaatgat ttattcttat
    35581 agtcttgtat ccttgcgaat catatatctt atataaagca ttacctataa ctgtagttct
    35641 tatgtgccct atatggaaag gttttgctat atttggagaa gaatattcaa ctattacagt
    35701 tttatctttt ccaaaatcac tatgtccgta attttctttt tcgtctaaaa cttttttaat
    35761 tacagtttct gctaattgag atttatttac aaagaaattt acatatccgc ctaattgtat
    35821 tacttttgtt atctctccac ttggttctat actttccgcc aattcacttg ctatcatgtt
    35881 tggagctttt ctaaacactt tggctaattt aaagcatgga aaagcatagt cccccatatc
    35941 cttatttggt ggaacttcta taagtgcctc tatctcttct ttcgataaat cttctatttt
    36001 ttctttaagg caatttgata ttgccacctt aaaatcttgc attctgttgc tcctctctac
    36061 attgttcctg gtttatattg tgcttatctc tttatgttaa atcaaatttc gtgttttttc
    36121 aagtatttca ttacagtgta aaacacttta gtaattatgt tttctgtata tattaaaaat
    36181 actataattg cagtttttaa tcacactatt attgattttt tataagactt ttttctattt
    36241 tattgtttct tgtactatcc agttgacttt atatactttt tttaatcttt tatctatttt
    36301 catacgtcaa tgctaatttt atatactttt cttttaatct tttattaatt ttcatacatc
    36361 aatgttaact ttatatacgt ttttttaatc ttttatctat tttcatacat caatgtcagc
    36421 tttatatact ttttttactc ttttatctat tttctataaa tctttttcac tcttaacttt
    36481 tattccttct tcttctaata gccttgctgt tatacctttc cctggtatct ttttacctga
    36541 aaaactacca tcatatatta gattacatcc acaagagggg ctaccctctt ttagtattgc
    36601 ttcgctacat acatataaat ttgctatttt tagagtttca ttagcccctc ttacaaagtt
    36661 ttctgttaca tccttattat ctttagtaat tacttttcca tcaactatct cagcaggtgg
    36721 tcttggtgta gatagaccac ctaactgctc tgggcataca agtgtaaatt ctttgccttt
    36781 taaatattcc ttgacttttt cattatcatt attatcgcca ctatatttac aatttattcc
    36841 tattaaacat gcagatacca atatcataaa aatgtgctcc tatacaaatt atatatattc
    36901 tcatacaaat tactaatgta ttcttataca aattatttta atttaacaat tgttactcct
    36961 gctccacctt ctccatattg accacctctt tgtgatttta catgtctatt tcttcttaaa
    37021 atgtcttgta gccctgcttt taatactcct gtacctattc catgtattac tgttacagac
    37081 tctaaacctg ccacatatgc atcatcaaga tacttttcta cttccattat agcttcttct
    37141 aggtttaacc ctctaaggtc aacttcattt tttacactac cagattttga ccttataatg
    37201 tttctcgttg atttagttac atttgttgaa acatctttgc gtgttttttg taaagattta
    37261 aaaggtagag tcatcttcat tataccaatt tgcactactg cttcttttct ctttttatct
    37321 actgaaacta cactaccatt ttgatttaaa gttattacct taacttcttc acctggcttt
    37381 aagtctttta tctccttatt tgataccttt ggaactatca tactttttac tgttggctga
    37441 agacttccca tagagctggt caattctttt ctaagttctt ctatcttacg attcttttct
    37501 tttgaagctc tttcttgttc aagacttcta agttctttta ttataatatc tacttcttct
    37561 ttagcttgtc ttataattga aaatgcttct gatttagctt tttcaatcat cttatctctt
    37621 tgactgacca atttttcaag tttttcgtca tactctactt tcagtttttc aatctcttct
    37681 tttaatcttt cagcttcttc tctatcttct actgctttga ttctattctt ttcaacattc
    37741 tgtaacacat cttctaaagc tatgttttct gtatttatat attctttagc acgtgaaatc
    37801 acataatcac ttagcccaag ttttctagaa atctcaaacg catttgattt tccgggaaca
    37861 cctataagta acttatatgt tgggcttaaa gtttctatat caaattcaac tgctgcattt
    37921 tctacacctg atttagtaag agcataattt ttaagctcac tatagtgagt ggtagctata
    37981 catttagctc ctacagaatt tatatcttct aatactgcta ttgcaagggc agctccttca
    38041 acagggtctg ttcccgctcc taactcgtca aatataacta aagagtctgc tgttacgttt
    38101 tgtaatatag atactatatt cgtcatatga gatgaaaatg ttgatagact ctgttcaata
    38161 ctctgctcat ctcctatatc tgcaaataca ttatcatata cacacatact acttccataa
    38221 tcagcaggta tatgaagtcc actttgtgtc ataagtgcaa atagacctac agtttttatt
    38281 gtaacagtct taccacctgt gtttggacct gttatcacca atgtatggaa gtctcttcct
    38341 aaataaatgg tatttgctac taccttcttt ttatccagca gtggatgtct tccatttttt
    38401 atgtttaaat atttatcctc atttaaagtt ggttctattc ctctcatctg tatagaaagt
    38461 tttccctttg aaaatgcaaa gtccaatctt ccaagtatct cttgattaga gattaaatct
    38521 tcgctcactt ctccaaccat agcagaaagc tctgataaaa ttctttctat ttcttcttgc
    38581 tcacctagtt ttaactgtct caattcattg ttcatctcta ctatagtcat tggctctata
    38641 aaaagtgtcg caccagaaga tgactggtca tgcactatac cagctacttg cgacctatat
    38701 tcagatttta caggtactac aaatctatca cctcttagag aaattattgc atcttgtaag
    38761 tacttttgat aagtagttga acttattatt gaatttaatt ttgacctaat ggattgattt
    38821 ttttgggcta ttcttcttct gatatctcta agtgtacttg aagcattgtc agatatttct
    38881 acttcactaa ttatagcatt gtatatctgg tcttctatgt ccttgtatac atatagagaa
    38941 tttgatagag attgtattat tggataatta aaatcttctt catcactact agataagcta
    39001 tttcttaatc ttctagccac tcttaaggta tctgctatca taatcagact tcctgggtca
    39061 agagaagcac ctatataagc tctctttacc ttatcttcta tatcatgaat accttccaac
    39121 cctactgaac ctctctttat aataattgat tgagcttcac tagtttcttc tagcatagat
    39181 ttcacttcta caaaatcagt atttggtact aaattttcta tatattttag acctaaagaa
    39241 gatgaggctt tcttctttaa caaatctatt attttattgt attctagaac tcttaacgat
    39301 ttctcattca ttttctatat tcaccatcct cgatatttta acttttttat ttaattttaa
    39361 aaatgtatgt tttcaagcat ttccaataaa aactgcaagt tttatttctt tttcatttct
    39421 aaaattatta tattttttct cttttagata tattttacac atattttgta ttatactatg
    39481 tatgtagcta tctatatatt atacataaac atgctttatt tgtaatataa tctgttaaaa
    39541 aatcttcttt aatattttta aaggagttta ttttagctta taaaaaaaaa tagctactta
    39601 tatagataaa ttaaggagga acatgagtca tgggaaacgt attagaagga ttaaaaccag
    39661 aaagtgtttt taaaaacttt gagaaaatat ctcaaattcc tagaggttct ggaaatgaaa
    39721 aaggcataag tgatttttta cttagctttg gtaaaaattt aggtcttgaa actattcagg
    39781 atgaaagctt aaacataata ataagaaagc ctgctacaaa aggatatgaa aattgtccag
    39841 gtgtagttct tcaaggacat atggatatgg tttgcgaaaa agaaaagaat gttgaacatg
    39901 attttcttaa agaccctata aaattaagaa ttgatggtga catgatatat gctactggaa
    39961 ctactctagg agctgacaat ggtatagctg ttgctatggg tatggctata ttagaagata
    40021 atactttaga gcatcctgca ctagaagttt tagttactgt taatgaagaa gatggtatga
    40081 atggtgcaga tgcactagac cctagcttaa ttaaaggtca atatatccta aatatggact
    40141 ccgaggagga aggatactta ttagttagct gtgctggtgg taaaacttgt gttgttagtt
    40201 tacctgttga atacaaggaa gttaaaggtg acaaacaagg attattagtt gaggttactg
    40261 gactattagg tggacactct ggtatggaaa ttgttttaca aagagcaaat gctaacaaag
    40321 caatagctag agtattaagt gtattgaatg ttgattatga attagcttct gttgatggtg
    40381 gtactaagca caatgctata cctcgtgaag ctaaatgtgt aatagctgtt aataaagctg
    40441 atgttgaatc tgctaaaaaa caaataaatg acattttaac tgcatttaaa catgagttta
    40501 ctacttctga ccctggcatg acttactcag tagctgaaac ttctgtagac aaagttctta
    40561 ctaaagattg taaagaaaaa gttgttcaaa tgtcttgctt aactcctcat ggagttcaat
    40621 cagtaagtct tgatatagaa ggattagttg aaagttctac taacttcgct ataattgaaa
    40681 ctaaagaatc tactattgaa tttttaactt ctgttagaag ttctgttatg tctattagag
    40741 atgaaatcgc tgatagaata agacttttgg ctcaagcttt aggtgctaat tacgacctta
    40801 tagctcaata cccagcttgg gaatttaaaa aaggctcaaa attagaaaaa atatgcagtg
    40861 aaacttatga gaaattaact ggtaaagttc ctactgttat ggctctacat gctggtcttg
    40921 agtgtggatt attacttgat aaacttcctc atgctgaagc tatctctata ggaccagata
    40981 tgtttgatgt tcatactcca aatgaacatg ttagtatccc ttctgtagct aatgtttggg
    41041 attatgttat tgaaatatta aaatctatga accaatatta aatttaagtt ttgattctaa
    41101 gtagatttta attttaagta atctatataa aattaactct gtaaattaat actactgtta
    41161 gtataatatt tactttcaat attaacttat agaaataaag cctaatgata gataataaca
    41221 tgtatcatta ggctttattg taatttaaat attattaagc tttattctgt tttaaaatta
    41281 attcttatac tattttaaat ctatttcttc cttgtctctt agaatcataa agagcattat
    41341 ctgctatttg atacagttca tcatactctt gaccaggctt tgctataact acccccatac
    41401 taatagataa actttcttca tttggcaact taatgagatg aatatgattg tatacatcat
    41461 tacatttatt aataagttct tccttattta ttatatcatt gatataaaca ctaaattcat
    41521 ctccacccaa acgacctact atatcatttt ttgcaaaact ttcatcaagt acctttgcaa
    41581 catcaataag tactttatct cctaacaagt gaccataagt atcattaatc gacttaaaat
    41641 aatcaatatc tataatcaat aaagcaccat ttttttcagt tgataaattc aacaaatttt
    41701 gtgcagttaa ttttctaata tatgctgcat tataaatatt ggttaaacta tccctttgag
    41761 ccttatctaa caatctattc ttttcctctt tttcagaatc aatattacat attttcccga
    41821 ttacatacat tggtattttt ctatcattat aaattatttt tgaagtaact ctaatccaat
    41881 gaaaagtatc atcaagcata atagaataca tttcagttgt tccattttct tgtgatttta
    41941 ttacatcaaa aaacttttta ttatattctt tccttatttt atctctttca ttttctatat
    42001 tgccattttc actttcctta tcatttttat ccaaaccata ataagtctca ataccctttt
    42061 ctggcataga aattatcaat ttatcttgct tataatcata ctcaaaaaag tattcacttg
    42121 tcatttcata caactgagta tgttttttga gttctaaaga tatcttctcg ttcatacttg
    42181 tacgagtatg caaaccaaat gccataaatc caataataca aattaataaa ctggctacaa
    42241 taaaaatagt ctcaattgga ttctgttgca taatataaag caacgagaaa tcttgtctat
    42301 atgtagtatt ttggtagaca attgattgca ttttttctga tgaaatactt ataatagctt
    42361 tattaaatat attcaataat tcttgtttat cttttttaat tataccaaaa caaatactct
    42421 ttgctttata agtttgagga actagacgca catttttata cttaggttga ttcatatagt
    42481 actgcataga ataaccttcg ccataagtgt aatctgcata gcctttatta acagcttcta
    42541 tacaatcttc taaattatca taccaaacta tattctcttc aaactgacca taataattaa
    42601 tacctttggc tagagctaca cgttttccat ctaaactatt ctcatttaat ttattattaa
    42661 tcatcatagt atattgagta gaaagaaaag gccgagacat agctatatta tgttcacgag
    42721 agtattcata atcataaatc attcctgcta caatatcaat ttcacgcttt ttagtcatgt
    42781 tttctaaatc ttcttgagat tttacaggca caagttcaaa ttctaagcct gttttatcac
    42841 atatatgatt taacaaatca attgatatac ctcttaattc acctgtatct ttatctatat
    42901 tttgaaatgg tggtttgttt aaaagtactc ctacttttaa tttttctgtc tctttaatgt
    42961 aatcagtttc ttcatcagat aaaaacattt gattattctc tggcgtaaag tatttctcat
    43021 ataaagtagt tgaaaaatat gggtccttct gttcaatatt attaattgct gagttaagct
    43081 tttgagttaa atttgtacta cctttaggag taatgaaata aaatggtttt gatgaaaatt
    43141 ttgctacagt acgtacacct tctattgggt tcatactcac attaagaagt acatctgctt
    43201 taccactctt tagtgcttct agttgctcat catttgtttt acaatatacc aattcaggtg
    43261 acataagatt cattttacaa tactcatcta attctttaag tctagtatca gaattttcta
    43321 ttacagcaat acggattttt ttcacatctt gtgaactcat tatgttatca atatctgtat
    43381 tttcatataa tgcttgtagt actgtatttg ctactccata attattccct gcataattat
    43441 atattttttg cattggttca ttgtataaca tacctcccat tatatcaatt tcaccatttt
    43501 ctaacatctt cattaatttt gtaatagatt catttatctc tccaggaact tgaacaaatt
    43561 cataattcca tccagtatac tgtgcaattt ctagtaaata ttcatatgta tacccaaaat
    43621 agttaccttg ctcatctatt tcagttaaac ctttttgaat aggataagca acacgaatgg
    43681 tacgattatc attacctata gcgttgatac caaaagaaaa tatgcaagaa gtgaatatag
    43741 atgtaattac aataattaat aaaagtaatt tttttaaatt cactacacaa tcctccatat
    43801 agttaagatt tacagtataa attactgcat aaacttgtag acatgtaaaa atagattagt
    43861 atataaaagg atatataaat ctacttagaa atttaaatat ccttaatata tacaatatat
    43921 ttaaattata actcatttat atgtctatta caacaaattt accctgctaa atacctactc
    43981 tatatcccat aattttacaa gttgtagtga agtttaagtt ctatctcacc tcaaatttag
    44041 cagtgtttct atttacagtt cttttatatt tcacatctgg ataacccaat ataaatgaag
    44101 tgataacagc ttcgttctcg ctcattccta acagttcttt tatctttggc tctacatttg
    44161 atgccataac aaaaaatcca ttataacaaa ttcctaatcc ttgagaatag gccataagtt
    44221 ccatattaga tgcagccagt cctccatcta cataagcact tccacctaga gacatatcac
    44281 ctacaactac cataagtagt ggggcatcat aaaataaaga atcatttccg ttctctttgt
    44341 atcttttgta cattttctta aatgtatttt tatagataga acgtacaggg tcattgtcat
    44401 cagtatctaa tgccaaatta taaagacctt gtattgccag ttctttcact tcttttagct
    44461 tttcttttac taatatgtat cttataggct gtctattacc acctgttggt gtgtatctac
    44521 cagcttccac tatgtttttt attttttctt cttctacctc tatatcttta tattgtctta
    44581 tacttcttct aaatttaata aaattcaata acttttcggg ttctaattca aaactttcac
    44641 gattgtattc tattacttca tttttatcaa atccttgcat ttctattgca tctgttgggc
    44701 aaattgccat acagtgacca cagttaatac agagaatatt tttaaccttt gctttatcat
    44761 ccttaacttt tattgcattt acaagacagt ctgattcaca catcccacag cctacacatt
    44821 tttctaaatt tatgtctatc attccaaatt attcctcctt ttaaaaaatt tactttagta
    44881 taaaacaaat agttgtctaa gtcaattttt atttttttaa caatatacta gccttaacta
    44941 cactttaatg gagaaaaata tacataaatt ggaacttaaa ttagaactta ttcaaagtaa
    45001 aagataaaag aagtagatgt ctaaaagtga actttttagt taattagata ttctttattg
    45061 tatgaaatca agtggatatt tatcatttca acaataaaaa aggcttacct ctattttgga
    45121 tatgtccctg tcaagtagac atactaaaaa aaggctatct ttatgcactg agatagcccc
    45181 ttttcccaac tactattgtt tatcttaata ttagtcaata aatttaattt gctataacct
    45241 gtaagttaca ttttaatttg atgtaacttt aaattacatt tttaagtaat atctttaaat
    45301 tatattctta aaatatatca ttaaactaca ttttaattaa tctaaaaact atatcttaat
    45361 taatctaaga aacttacatt ataatctttt agtttcccat tatcatatat aatctttgca
    45421 ctaaagatat ttccagtctt agcccaattt aagaacagcc tgtcaccttc ccacatattt
    45481 aaatcgaata ttttatcatt atcaacccaa attaaatttc cttctttaca atcatttaaa
    45541 tctttttcag ataattcacc ttcaaactca tctgagaaat acaaaaacat ataccaatct
    45601 tcttcatctt taaattttgg aaaagttatc aaccctttat atgacaatga tttaagagta
    45661 agaccagtct cttcttttac ttctctaatt acacattctt ctggagtctc tccttgctca
    45721 aactttcctc caactcctac atacttacct tcatgtatat catctttctt tttatttctg
    45781 tacaacatca aagtcttgtc atctttttct atataacaaa tagttgtaag tttcatgtat
    45841 ctcgccttgc tttctctttt atattctcaa ctaattattt tcagcacttt caagcacatc
    45901 acttatattc ttcattgcat taagagaaag ctctgcaaat tcatcaaatg gaatccctat
    45961 atcttctata cttctcattg catctctatt tacatttgaa gcaaatctcg tttctttcat
    46021 tcttttaata acagacttag tctttacact ggtaagtttt ttatctggat aaactaaagc
    46081 tatagcagtt ataaacccag ttatagggtc tgctgcatat attgcttttt ccattaggct
    46141 agttcttgta actcccattc catcatgatg accaagtatt gctctataca tttcttcgtt
    46201 accgaagttt tcttttttaa gcagttctac tgttgttgta gcatgtcctt cacatatttc
    46261 tcctggcttt cttccaacta tatctgaatc caaatcatgt aaaagacctg ccactgccca
    46321 ctcttcttct ttttctggct ctagtctttt ggctaattct ctcataacag cttcaacagc
    46381 ataacaatgt tttctcattc tatcagtttc taaatactta aataaaattt ctaaagcttc
    46441 ttctctcatt ttcaccaatc cccctgtttt ttcacatata tgatattttt atatattaat
    46501 acacataaat tcaagctttt atatatattc atgtatattt ttcatgttat atctattcta
    46561 cacctttata gtagtgtcct gcaactgttc caatttcatc taatttctta tacaagtctg
    46621 tagccttttt tccaagttta taattattac tcagtacctc aatgtgagct tcaataacct
    46681 ttttaaccat ctcactatct tcaactgtaa aatctatcct aaatacatct attccaattt
    46741 cctctaactc atatagattg tccaacatac aagtaacctt cgaattgtaa attgtacttc
    46801 tacagaatat atcttgtgtt atcctataac ttgcatccgt aaagtctctt aaagcataac
    46861 tactttcctt acatttagca actctcttgt cctttttaca atctctaaca actactccca
    46921 taggacagta ttctgtaacc atcataggag catatccata tattactgct tcaatttcta
    46981 catctgtata ttttaaagtt tgtttaattt catttaagtt tagttcttgt gacaaacaaa
    47041 ctgtacttgc tccctcttct ttgaagtgat ttatactttc actattgaat gcatttaagt
    47101 agcaatctat atttaagtct tttttcttaa agtattccat agagccccag ttaccaattt
    47161 gaaccttatt aattcctttt atattatcca atatctcaaa ttgcttgtac tctttatttc
    47221 taacaatcct tggtgctgaa tagattaatt ttttgtcagt gactgctgta ttagagtggt
    47281 tcttattcaa agtatctatt ttacttgtat ttgacaaagt atctatgtta tttgtatttg
    47341 aacccattag ttctttagga gtacctaaag acgaagaagt atctaaatcc atagaaatac
    47401 ttgaatctat agaaatattt gaatctatag aaatacttga gaccatttgt aaagcttttg
    47461 ataatgtatt tatatcttca taatagatta aatctacatt ataatttaat actgcttcta
    47521 attgctccaa gttcttaact ttaactctaa tcttaggagc tgtatcaagt tttttctgtt
    47581 tatttactct atttggctgg tattttaatc tattcttctt aaattttcta tcttttatct
    47641 ttattctttc ttcatctaaa agctcaatac aatcccttct catttgattt aacacactta
    47701 taggcatact tacaccttca tccaggtcaa tttctatctc ttttaactta tatggtgtat
    47761 ttccaagctt ttgaatttgt gtttctattt tttctttact taaagccacc tttatagctt
    47821 tttcaactat tttgtctcct tctaccaccg atttatttcc acaaaaatca cttataaaaa
    47881 gctctggctt tttacctagt ttaatactca cttttgcacg tatattagtt tttatgaact
    47941 ctttatcttg ctgaaatgta gcttgtactc tatccattaa ttcgctgtca gaagtcttat
    48001 atataagctg atttctcttt gcttctccaa caaaatctaa ttctatcaaa tcccctttat
    48061 gtgctattgt agttatctct ccatccttta ttattcttcc aatagtacct ccacctaagt
    48121 taattccatc acctttctta agcgtatttt ctagcattac tctaagtctt ttgttctttc
    48181 tattataatc taaaactttt ccaatatata gcccttgatt attaggtcta ttagagttca
    48241 ttatatcctt accaacttca cctaatatat atccttttgt aaactttcta ttaaatatgg
    48301 tatacaaatt atttattatt tcctcagaaa tacttatttt tttcttatct acaaattcat
    48361 taatcgcttc tctatatcct gaaaccacag tagctacata ctctggcttt ttcattctac
    48421 cttcaatttt taaagataat acacctgctt caattatttt atccaaatct tctatagtac
    48481 ttaaatctct aggactcaac aaataatctc cattactttt tactacttct cctgtattta
    48541 tatctatcaa ctcatacttt tgtctacatg gctgtgcaca cctacctcta tttccagacc
    48601 tattgcctat catactactc ataaggcatt gacccgagta acatacacat aaagctccat
    48661 gtacaaaaac ttctatatct acagttgtat tttcacaaat ccattttatc tcatcaacat
    48721 ttaattctct tgctaaaaca actctatcaa accctacact ctgaaggtat tttacatctt
    48781 ctaaggaatg tgctaccatt tgagtgcttg catgtagttc aaagtcaggt aatagttttt
    48841 ttataagtct tgccattcct atatcctgta ctattaaagc atcaatatct atatcgtata
    48901 aaaattttac atactctaaa aaatcttcta tttcatactg ttttatcaat gtatttacag
    48961 taacaaagac ttgcactccc cttatatgag agtatttaac agcctcaatc agctcatttc
    49021 tatcaaagtt atttgcagat gctctagcac taaagtcttt accacctaaa tacacagcat
    49081 ttgctccgtt ttgaactgct gcttttaatg aatcaaaaga gcctactggt gcaagtaatt
    49141 ctattttttt catatttttc tcctctattt atacttgtta ggttaatata attatatcta
    49201 taacttaaat atttgtatta aatttatata tttcttacta tattttaaat tcttcaatta
    49261 atttatatat tagttattt
//
LOCUS       DAEPUT010000021        48244 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.021, whole genome shotgun sequence.
ACCESSION   DAEPUT010000021 DAEPUT010000000
VERSION     DAEPUT010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48244
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.021"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..1019
                     /locus_tag="KRL22_001349"
     CDS             <1..1019
                     /locus_tag="KRL22_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBH1271851.1"
                     /translation="EKLYYTALIGYIFYEAPREEKNFATLLDMIDASEVREDDETYMN
                     PIDRLFEALEKKEPTHFAVKQYKKYKLAAGKTAKSILISCGARLAPFDIRELRDLMGE
                     DELELDTLGDRKTALFVIISDTDDTFNFVVSIMYSQLFNLLCDKADDVYGGRLPVHVR
                     CLLDEFANIGLIPKFEKLIATIRSREISASIILQAQSQLKAIYKDNADTIVGNCDSTL
                     FLGGKEKTTLKELSETLGKETIDLYNTSETRSNQKSFGLNYQKTGKELMSQDEITVMD
                     GGKCIFQLRGVRPFLSDKYDITKHKNYKLLEDYDKRNLFDIESYIKRKGKVKMNRHTV
                     ITRL"
     gene            1183..2049
                     /locus_tag="KRL22_001350"
     CDS             1183..2049
                     /locus_tag="KRL22_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009731661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1271852.1"
                     /translation="MNIIKSFNSTIDYLETVLDDEIDEKKVTRISGYSYSMFSRLFSI
                     LTEMTLSEYLRSRRLTEAAIILRDTDEKIIDVAFKFGYESSDSFGTAFKNFHGFTPSE
                     VRIGKPFKLVSRVQLALSVRGGRSMNIRIQKKKAFTVAGVNQQNINSSICASLWQKLF
                     SKVSHEEMLNLGTGEVVGVCHDILSLDNHDVLDSNTINYMAGYIVTDVDKARSMGLDI
                     LEIGETEYAVVELTGSVPECIHNGWKYAMEVFFPEHGYVHSGKPDFEYYYEGDMYSKD
                     YKMELWIPVCKS"
     gene            2258..2569
                     /locus_tag="KRL22_001351"
     CDS             2258..2569
                     /locus_tag="KRL22_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-strand DNA-binding protein"
                     /protein_id="HBH1271853.1"
                     /translation="MKQEMININANLLAEPTFSKFEKEGEKVEVANFTLVKKYGKGKE
                     YINCAAYGEKAKTVKAFEKGDLIHIFGYFKKREKDGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            2573..2788
                     /locus_tag="KRL22_001352"
     CDS             2573..2788
                     /locus_tag="KRL22_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBH1271854.1"
                     /translation="MEFFTQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            2808..3671
                     /locus_tag="KRL22_001353"
     CDS             2808..3671
                     /locus_tag="KRL22_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271855.1"
                     /translation="MFGIFDKIEEFFKEFLLGGIQANLESMFLDINDKVGAIATDVGK
                     TPMGWNGQVFSFIKSINDSVIIPIAGLIITAVLCIELINMVMQKNNMHDTDTFDFFKY
                     IIKMWIAVWLVSHAFEFSMAVFDVAQHMVNKAAGVINTSATVSGNQIVAMIDSLKDKG
                     LGELVMILFETSLIKVAIQVISIVIMLVVYGRMFEIYIYSSVSAIPFATMGNKEWGQI
                     GTNYIKGLFAIGLQGLFLMVCLGIYAVLVKTIKITDIHTSTFTILGYAVLLGLMMLKS
                     GTLAKSVLNAH"
     gene            3689..3949
                     /locus_tag="KRL22_001354"
     CDS             3689..3949
                     /locus_tag="KRL22_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1271856.1"
                     /translation="MNKRKTVFIVVIGAGIMAVIDRIRLHSKVNDLEERKKDIGRCHN
                     DFCLMQERFNRSIDEQITSIQEEIGSVYEHIEELSKGKEDGR"
     gene            3953..4342
                     /locus_tag="KRL22_001355"
     CDS             3953..4342
                     /locus_tag="KRL22_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBH1271857.1"
                     /translation="MAYVPIPKDLKKLKTKVAFNLTKRQLIGFTIAGLIGIPIYLFMR
                     KVVPNDIAVIFLIVSTLPIFFITLFEKDGLTFEKYFKYIYLHKFYQPQKRVRKEVYLE
                     QKKKDSAAKVRTKQKEVKKSKTGLKAK"
     gene            4254..6683
                     /locus_tag="KRL22_001356"
     CDS             4254..6683
                     /locus_tag="KRL22_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1271858.1"
                     /translation="MNKKRKIQQLKLEQNKKKLRSQRQDLKQNKGKSKKDKGGLLDPI
                     FRKEPKRYTVEDTIPYLRLLKSGICQIDENHFNKSIAFEDINYQLALEEDRDLIFNQF
                     ANFLNSFDPSISIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERMEIDILSSFKSMGVRAESLNGEERLKILHD
                     VLNPNKTFEFSYKDLKKKESTKTYIAPDEFNFTPSRYFKFGNFIGAASHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIEQSEAIKMVKRKNTDIDKMKIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVTIIFMNFARTIQKLDNTISQISSIANKH
                     NCKLKRLDHSQEQGLISVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSANSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILTTDDDVIICDPEG
                     EYGNLVRQFKGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYGKYFENPILENMPILQDLYDMLKNQEEKVGKKLATEMEIY
                     VTGSLNVFNNRSNVDLNKQLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTTSYSVEIWKRFRKWGGIPTGITQNVKDLLMSNEIENIFDNTDF
                     VLMLNQASGDREILARKLKISQPQLKYVTNSNAGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            6688..8850
                     /locus_tag="KRL22_001357"
                     /pseudo
     CDS             6688..8850
                     /locus_tag="KRL22_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426100.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
     gene            8862..9095
                     /locus_tag="KRL22_001358"
     CDS             8862..9095
                     /locus_tag="KRL22_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1271859.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIAI
                     CRKNNITISDLMAKVNREKSEMKKENGNEKNEE"
     gene            9076..10650
                     /locus_tag="KRL22_001359"
     CDS             9076..10650
                     /locus_tag="KRL22_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBH1271860.1"
                     /translation="MKKMKNKKAAGVILGAVLLIVGVVISLFAGSKIVFAQGGLFTTL
                     VNPIEAVAQIEVEVNVKYIFEDEKVFKEEKIKAEKEWLLDSGDLPIIPDDMKFIDEFL
                     FYEVKGDGKDEIIRKVTKIDVKDKETQTENESSKSEQSSQSNASKIENKGTQTELSKD
                     DISKMERESKELKEKLDKLNQEIKDKDKLSEKQKDKIKDLEEKIDKLKEKLEKGKDDK
                     DLSADMKKEIDKLTDKIKELEKKANEVGRAPIMHNPNVTPISPISGIKQGTGNVSPQT
                     SINSSGKGSATQESKGANTKDTNSNESKEKEKQVRYPNKLTPKQPANNGSHDSSLDGS
                     SKNINTNKGVASEPSKARGTVTENKDNANKNYPIHHNDSKDNKETDKYSADARQFVTF
                     TTKNGKTFHLIINHDEDSENVMLLTEVSEDDLLNMVEKKAPEKEIVKEESQKEEPKQV
                     KKEESSNTGTYLILILVVAGALGAGYYFKVIKKKEDKELEGFEEEDDDFFSEAEESEN
                     EVNEAVTEDKEDDEIE"
     gene            10746..12452
                     /locus_tag="KRL22_001360"
     CDS             10746..12452
                     /locus_tag="KRL22_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBH1271861.1"
                     /translation="MKLVIAEKPSVAISIAKVIGATKKKDGYYEGNGYKVSWCVGHLI
                     QMANPESYDEKYAKWNMADLPIIPREYKYEIAKSTKKQFTILKKLMNDKEIDIVINAC
                     DAGREGEAIFRLVYNQANCKKKMKRLWISSMEDSAIKEGFDNLKDGSFYDNLFESAQA
                     RAIADWLVGMNLSRLYSCLYKQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYFTVELD
                     LDGFSLSTDRIDDKTVTEQLINLLGNSIEITDVIQKEKITKPELPFDLTTLQRECNKY
                     LNYSAKQTLDYTQSLYEKKLITYPRTDSRYLTEDMITSTINNIIGKHDFDTGRIKMVF
                     NSKRVTDHHAIIPTASSMNEDLASLPESELKVYELVLNKLHASVGYPLIENTTKIVAV
                     FDGFEFTSSGKVIVDEGFTKYLKKYIKKKNEDTVFPDLKIGDSLDIKEKEIKEKYTSP
                     AKHFTEDTLLKDMELAGNDALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNL
                     IATHKGISLVTIVSDTFKSAGTTAKWEMELSDIAQGKASKENFLKAIENEIKELVSTY
                     SK"
     gene            12536..12721
                     /locus_tag="KRL22_001361"
     CDS             12536..12721
                     /locus_tag="KRL22_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBH1271862.1"
                     /translation="MSEVFMNNAKVMAKGQVTIPKKIREILEIENGDYVTFVVTEGKI
                     QIVNSKTFIEKNIQGRK"
     gene            12755..13801
                     /locus_tag="KRL22_001362"
     CDS             12755..13801
                     /locus_tag="KRL22_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 family protein"
                     /protein_id="HBH1271863.1"
                     /translation="MNKEKNSLQNINIEKNNNSFEEIVMIVENAKDRAYRKVNEELIL
                     MYQEVGKYISEKTKEASYGSGFVDNVAEFFSINYPDLKGFNRRGLYRMKQFYELYKDD
                     EKVSTLLTQLSWSNHLKIMSGAKSREEREFYINLAIKENLTHRELVRQMDSGYYERCM
                     LSNEGNMPAIQRAKQETHNLFMDSYVLEFLDAPKIGNEREFQKSILENLKNFVLEIGK
                     DFSFIGNEYRVQVGNHDYYIDLLFYHRGLSCLVAFELKIGEFKPEYVGKMNLYLEALD
                     REVKKQAENPSVGVILCASKDDEVVEFALSRSLSPTMVSEYRLKLIDKELLQRKLKEY
                     TGIAEQEIERHDEK"
     gene            13912..14718
                     /locus_tag="KRL22_001363"
     CDS             13912..14718
                     /locus_tag="KRL22_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1271864.1"
                     /translation="MRTGNEFNGVEDTLYIPLAARIYVSEKFPHFFYDEKALSLKPKI
                     PTGGIDNNSTEYFYMASVCRQQTIDMKIKKFLDENKKGNMVFLGAGLETSYNRIGNQI
                     VNFYQVDLPGVIEVRKRVLGNAKNEKLISGDMFDLNWIKEIDTSLPTLISVAGVYQYF
                     DEYKIIDMIQKLKAQFSKGELIFDATNSKGLKLANKYVKKTGNKNAQMYFSVDNSKDL
                     ADKTGTILLEVDGFFHGALKACQGLKLMTRLYMYFADKLHRTLVIHLRFN"
     gene            14831..23812
                     /locus_tag="KRL22_001364"
     CDS             14831..23812
                     /locus_tag="KRL22_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBH1271865.1"
                     /translation="MRINDFHNILELVKQDILQSEAEYLKLLKVVGNNQRYDFRSQLS
                     IYDKNPEATACAKFDYWRERFNRTVMRGQKGIPILEDYGTYKKVDYIFDISQTVSKNR
                     DVNEVNLWRFDKEAHKDVLKEMIKTEGYEESESTLENIFSLSRLYGDEKIDNLMNELR
                     IADEDRISFTKFVRDSISYAVASRFKLDYPMDKELLKENFAMLDSISLMSLGETVSDI
                     SGTVIDTTIQKSKELELKKEVLRGKEAGYNKIKEELEEVEENVLRRDDQERISENERI
                     FRNGKYGRDNRENQGEYTESVRGRDGLYEGISESSVRSDEAELSFKQRRAEPLRDVSG
                     SIQGEEADQTPDGYSETGDRVYESRKAKTDDVLADREREPSSVQSNDFSPQRNDNQGS
                     SGNLKENTDKEIREADKASFSLPENSSGQIKLTIPLAQNDIDSILVNGGNHEGGRLPI
                     IAEFSKGKTVEKLGEYLKDTMGGGNGFFLNGTEVSSWYSDKGIHLAYGTSAREDMTQI
                     LSWSDAARRINELLENGEFATNVELLEAQDYERNRISESLWYLYHDLSEEGKAQGYFD
                     FIETGGGFPKETRQLSEALKNPDYLKDVVSEYSRFLTGYKENKEVLRFHYHKVDSLYQ
                     RLQELALTRKEYTSNLIELPKIQGFITEDEVLATISRGSGVDKGKERITKFFKENHTL
                     QEKANFLKGEYGIGGGSHAVSGERGSGEWHDAKGLKLQKNHCNDVFLTWSNVAKHIDE
                     LLSKNLYLEEKNIEKKVEIEEQKEPSYYSKDDPYNLITDEMLEKVPELYAQEDVALAD
                     KQVHAAYIIPFRSNWTWYMTEYDRESKDAFGLVLGIEPEWGYFNLDELKELNAQRLVL
                     EDFPKTFRELKDSELKKQMDEQELYQVFNGELSFEENNIELEAPEDVEESKQAEPFQA
                     TLFDYLKEKEEVELNEKENSLSDEFTVKEGDTVYFNHEEYKVRDLSKNQITGKNDLWL
                     DPVRQGNHQIPIVAFTDNEDLLRQISLERPEFIIGDEVKYKGKDYAITKFDNMGNNLK
                     TVTVKDNTEYLGGMITGSDVIPYRQESELNKIFENLTYKKEELYDLAVRIDEIAYDFD
                     SYDYADSVEAESEKRLDNINQIYGDLQAGNVSVYINSLNEMIEEDVEDTEIIKQVLTQ
                     LEEKKIDIQPKQEVFNFKITEETLPQRLSPSERLNNNLEAISMLNRVESGERELDITA
                     QEVLAKYVGWGGLSDVFDESKDGQWKDARAFLKENLSSSEYEAARESTLTSFYTPKIV
                     IDGIYKTLSGMGFKQGNILEPSMGIGNFIGNVPDEMGKSKFYGVELDSVSGRIGKLLY
                     PESEVQVKGLEETGFSNNFFDVAIGNVPFGEYKVNDREYNRNNFLIHDYFFAKSIDKV
                     RNGGVITFITSSGTMDKKDESVRRYLAARAEFLGAIRLPNDTFKGVAGTEVTSDIIFL
                     KKRDSVLERDEAWIHLSEDKNGLVYNKYFVDHPEQVLGSMREVSGRFGKTLTCEPIAY
                     LGQEINMASLKERIEIAGERISKDTKYEEIELLDDEITSIPATDDVKNFSYTLNDDEV
                     YYRENSLFIKKEVSDKNKEKIKDYLELNVALKDVIYKQKEDFSEEEIKASQEKLNEVY
                     DNFSKKHGFVNNLSNTRALKEDSNFPLVSSIEILDEEENFKAKGDIFSKRTITKAKVI
                     DHVDTSLEALVLSVSEKGYVDFDYMGSLTGKDRATLIEELRGEIYLNIREEQNFYRSL
                     SFNPEDGDLPFACANGSNSYKYGYVTKDEYLSGNIRDKIAIVDSYLSKLRQTERELPH
                     LGFVENGKEKELISYEMNRLEYQKAELTKVLPKELEASEINVRLGATWIPIKDIEKFI
                     FETLKTPGYARWDIKVKFSNITSEWNVEGKSRDKGNDLAEMTFGTSRVNAYKLIEDAL
                     NLKETKVFDQIINPDGSKTSVLNKKETMLAGQKQELLKEEFKNWIFNDQERRNRLVKL
                     YNERFNSIRNREYDGSNLSFEGMNTEIDLRPHQRNAIARSLYGGNTLLAHVVGSGKTF
                     EMVASAMESKRLGMCSKSLFVVPNHLTGQIGREFMQLYPSANIMVADKKDFEPKNRKR
                     FIGKIATGEYDAVVIGHTQFEKIPMSKEYQEKHIQDQINEIVNYVEEYKHDRNQNFTV
                     KQLEKTKKKLETRLEKLNDDFKKDDVITFEELGVDMLFVDEAHNYKNLYLYTKMRNVA
                     GIGQSEAFKSSDMFMKCRYMDEMTGGKGIVFATGTPVSNSMTELYTMQRYLQYESLKK
                     NHLEHFDSWASTFGETQSSFELSPEGTGYRVKTRFSKFYNLPELMSMFKEVADIQTAD
                     MLNLPTPEANYEVIKTEPSEEQKEILKSLSERADDVRNRVVEPDVDNMLKITNDGKKL
                     ALDQRLINPLLPDNPDSKVNVCVKNVFAIWDKTKENRSTQLLFSDMSTPKGDGEFNIY
                     DDIREKLVAMGIPKEEIAFIHEANSDKQKDELFAKVRKGEVRILMGSTQKMGAGTNVQ
                     NKLIALHDLDVPWRPADLEQRAGRIVRQGNENEKVNIYRYVTENTFDAYLWQTIENKQ
                     KFISQIMTSKTPVRVAEDVDESSLNYAEIKALATGDPKIKEKMDLDNEVTKLKMLEAN
                     YKSNRYRLEDKVAKNYPEEIARTEKLIEAVKKDIASVEPKAEGEEKFTSITIAGEKIN
                     DKKLAGERLLEAISKVKINESKVIGKYRNMDLEVSYNFFTNEHNFSLNGAAKHSGELG
                     TSADGNITRLDNALEKMPEKLNRLEEKLISTKEQLQNAKEELKKPFEKADELKTKVLR
                     LAELNKLLDMGEVEEKRNDNPLVEDVKMAIIDFCNREYEENHSYDEFNTLYPDLKHIG
                     IAYTNTPDERHGIQYELDLEEKTWTQYIDGTPIKTESFYYENKGENEALRNMKNEIEL
                     FSFNDLVYVDSEDLKAALGLDIDDEGNFYDPLSKDLDNDGIADRYDNDFRDSDYFEST
                     YDVEDNLNTKVESVTKAEDKPSILSQIRAYQNESKTEEKQKTKEQEILR"
     gene            23855..24514
                     /locus_tag="KRL22_001365"
     CDS             23855..24514
                     /locus_tag="KRL22_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1271866.1"
                     /translation="MDYKTMINQIEDMVNYNHKDFVKAIISMEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGEVDVVEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGGKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHRNIRILSSKLLKEKEQMKGQEEKKESVLGAIKKYQAEDKEKPKEKKEANQEAE
                     R"
     gene            24655..24867
                     /locus_tag="KRL22_001366"
     CDS             24655..24867
                     /locus_tag="KRL22_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001263549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1271867.1"
                     /translation="MRAFSYKRLFKKLIDLDMTNNELMEKAKVSKSTFYKMKNGQNVT
                     TDVLLRICNALDCDIEEIVECIRIDK"
     gene            24888..25916
                     /locus_tag="KRL22_001367"
     CDS             24888..25916
                     /locus_tag="KRL22_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009643545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4297 domain-containing protein"
                     /protein_id="HBH1271868.1"
                     /translation="MSKEKYYMNLPKDLSGSIAKNRFRLELLWGISKIIDEHKANNEY
                     TIIFDFKCDIELHKEDELDFYQIKTKKSGNYNSNNLCKKGKNKNNSILGKLYALYSPN
                     YNIKLAIVCNKQLKINNKEIDFPEQCFGDLDQDVLDDVRKKLCTELNLDTVCLDNVFY
                     IFDNMDLLNPEDSIRGKLVKSFVDIKGEEPQNPNALYRLVVDSVKEKASYEFDSGTYE
                     DVVKNKGITRSEFDKMLNAHKKESKNGINETQEYINNLSFAKRRRYNTALGNILETQQ
                     SESLRLIKIKIYNYIVEHENSLDDIESYLKEISKLFDDDFDVEFTDDMKSVQYIMIYY
                     MYASGGIL"
     gene            25916..27598
                     /locus_tag="KRL22_001368"
     CDS             25916..27598
                     /locus_tag="KRL22_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBH1271869.1"
                     /translation="MNVIFDKIYIFDVVKKKAYSTEFKKGVNIITSSDIDGTDRGKSV
                     LLRSLYHALGADSHFDSKWGEKDKVYILFFKVDDKDFSIYRSQKLFKIFNAKGDLIFT
                     TIHRSELADFFGNLFNFSICLPQKNTNQLVIAPPAYSFLLNFLDQDEYIGTKFNSFKN
                     LAQFSNFKLNVIYSHLGIYNKEYFELVKHKEELELEIKSKKEEIEDLIKMKDRTILIL
                     DGFSCPETSSALENELNIETQKYSSLINEMNLVRNKLVDLRNQLVEQNITLSQISKFE
                     IKEEKEIKTILKSKVCPECHSVLDSTLELRSKRYNHIDNALSLKDAIKTENAHIEDEI
                     LKNEGIYSNLTLVLEEHNKKICKNKKEIKDYIKFRGLNKLIDEINNDLTINSRVIDST
                     KEALKPLKKEFKSVKDKIKSVDENYYYLIDKLKIRFNLNELEADSYEQLSKNFCASGS
                     NKPLSTVIWYLTLNDLKQKFNPEGTTFPMVFDSPNNAETDQEKKQALVEYIMESSDQF
                     SQLIVSAIGFSEKDYSIDSNINIKVLENEKYSLLNSEMYVQNYELLQCMNDA"
     gene            complement(27625..28956)
                     /locus_tag="KRL22_001369"
     CDS             complement(27625..28956)
                     /locus_tag="KRL22_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBH1271870.1"
                     /translation="MAITKIHPIKSTLNLAISYIVNGEKTDEQILVSTHKCHQETAHT
                     QFLRTRNDVGTNGTVLARHLIQSFLPGEASPEMAHQIGMELCKKILKDEYEFVLSTHI
                     DKGHIHNHIIFNNVNMVTGKCYHSNKKSYHQIRYQSDKLCKENNLSVIDKFYESYKRK
                     YKTNGKSWYENEQSKKGTSWKSKLQFDIDRLIKQSKDWEEFLKKMAELGYEIKYGKHI
                     AFKPKDKQRFTRAKTIGEDYTEERLKERITENQTIKTPPVKKRIGNVIDMNTNVKVKE
                     SKGYEYWATKHNLNTMAESVIYIREHGIKSVKQLDEYIQKVADERQNLQDKIKIIDKE
                     MQELSTTMEKVHTVKKYKQYYMEYKANPSDKAFFEEHKAEITRYETALAKLKKSYSKL
                     PDSKGILDKLDKLQEKKNTLMQEYSSTKSTMDELYQIRKNYGIYMDKEMER"
     gene            complement(28962..29312)
                     /gene="mobC"
                     /locus_tag="KRL22_001370"
     CDS             complement(28962..29312)
                     /gene="mobC"
                     /locus_tag="KRL22_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBH1271871.1"
                     /translation="MANRIRNERLEIKLTEEEKALFEEKRKLARCRNMSHFIRKCVLE
                     KEIYQVDLEPFRDLQGLLSNATNNINQIAKRVNSTGVIYKDDINDIKNEIEHFSKELW
                     QIHSLLLNRTSGGD"
     gene            29621..30778
                     /locus_tag="KRL22_001371"
     CDS             29621..30778
                     /locus_tag="KRL22_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBH1271872.1"
                     /translation="MKKIVSRGACLLLALCLSLNAVGCQKSNENNKIKEGQSISSEEA
                     GMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSDKFRNYIADKKIAMLDDQSP
                     IDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELERIGTIGIFEKNTSEEKISK
                     ITKCDTHTKIGVSSDGKYDCYLSTNSGAESNLLDELKRTEIQIIDKKERPKNGFVLSE
                     KTDLENTEAFNKESVKDLRKLSTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEI
                     PDLVEVQNEMKSKGVNIVGVVTDTVDDNGENKEAIEKSKLIHEKTKASYPFLMPDKTN
                     FNGRLNGIQAMPETFFVDSNGNIVGDTYSGAKSAKEWKQVIEKELEKIKNK"
     gene            30868..30963
                     /locus_tag="KRL22_001372"
     CDS             30868..30963
                     /locus_tag="KRL22_001372"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH1271873.1"
                     /translation="MAMIYYGHSNGETKVVLDKAIRICMECIGIG"
     gene            30956..31846
                     /locus_tag="KRL22_001373"
     CDS             30956..31846
                     /locus_tag="KRL22_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1271874.1"
                     /translation="MDRIKNIINGSTKKDKYKIRDRFRHLLQSVWFLITNSYFEGFKT
                     GKIYGGNLKKICVPGMNCYSCPGAKGSCPIGSLQAVIGNSKYKISYYIVGILFFIGAL
                     VGRFVCGWLCPFGLIQDLLHKIPFFKKVETFKFDKHLRKLKYIILLVFVIILPLFLVD
                     ILGQGSPYFCKLICPIGMLEGGLPLVLLNKSMRSAIGFLYYWKGIILIVTLLLSIIMY
                     RPFCKYICPLGAIYSIFNPISIFRYRLDKDKCINCGKCKKVCQMNIDPVENCNHLECI
                     RCGRCKNACPVDAISYGVRK"
     gene            31865..33142
                     /locus_tag="KRL22_001374"
     CDS             31865..33142
                     /locus_tag="KRL22_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1271875.1"
                     /translation="MIKNAIAYITRKRNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIGENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQEIYTGLSSDFSENIVFVDY
                     STSQEILNKSENNKIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKHIIKIMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMLNITTLGQ
                     SYLILISIIVLSVVFASSLILIKKPKEILSKIS"
     gene            33152..33808
                     /locus_tag="KRL22_001375"
     CDS             33152..33808
                     /locus_tag="KRL22_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271876.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQKKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            33808..35184
                     /locus_tag="KRL22_001376"
     CDS             33808..35184
                     /locus_tag="KRL22_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1271877.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFDNITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSSKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDVHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFVGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIARQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFIIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            35282..35935
                     /locus_tag="KRL22_001377"
     CDS             35282..35935
                     /locus_tag="KRL22_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271878.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFINLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            35932..37251
                     /locus_tag="KRL22_001378"
     CDS             35932..37251
                     /locus_tag="KRL22_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1271879.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLVFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLELYSKSSEIKAFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKTRLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNRISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKALQDEEFFIFKIKIFS"
     gene            37775..38185
                     /locus_tag="KRL22_001379"
     CDS             37775..38185
                     /locus_tag="KRL22_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1271880.1"
                     /translation="MAKEYYLYIRGQKVKVSEDIYIVYWREKEHEKYLEQVDRKNHLL
                     FFSALDHDGHFTDNIVDESVDVEKIVETQMMIEAVRSAITRLNAEERDIIERLYFNDE
                     TVRSVAKLKSITHPALIKRRNKILEKLKKFIEEL"
     gene            38674..38826
                     /locus_tag="KRL22_001380"
     CDS             38674..38826
                     /locus_tag="KRL22_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271881.1"
                     /translation="MDNDWNGLADLIANLITKYAGVLDLENLPNPTPVKNTEDKNKFD
                     IAKSTD"
     gene            38927..40609
                     /locus_tag="KRL22_001381"
     CDS             38927..40609
                     /locus_tag="KRL22_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004819974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1271882.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIDGYSLEAQKSRMKVFALYNDYEIV
                     GEYEDAGKSGKSIEGRVQFTRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDFGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRVQTMEGRIQKAKEGKWNG
                     GFAPYGYQLIDGKLIINEEEAIAIRTIFDQYVNTSIGANGLSKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYRQVEQDDYLVAEGIHQAI
                     IPDELWQAAQVKLKAQAKKYEHVNKGKNMRTHLLSGIVKCPICGAGMFGNKSIKYKKD
                     GTKYKDFYYYGCKHRLMNRGHKCTYNKQIREELLDDAVAEVIIKLVSNPKFASMIQEK
                     INMKVDTSAIENEIDNYQNELRKSHSTKYKLIEEIDNLDVEDKHYKRRKNDLDDRLYR
                     MYDKIEELESQLIEAKAKKETIEVEKLTGDNIYKVLIYFDKLYKVMNDVERRQLIEAL
                     ISEIQIYEEKQPNGQWLKSITFKLPIIDEDLNISLENDEQVETCVLLQRRTM"
     gene            40852..43896
                     /locus_tag="KRL22_001382"
     CDS             40852..43896
                     /locus_tag="KRL22_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH1271883.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPSTAVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASTRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDKNGNTDVVEVKAGTVYIRELSAPAGYKVDTT
                     VYSLKVEAGKTATLNVSDTPKVADTLIELFKIDMETQKDNPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDGTTHYITKLADAYKVSGDSFYMQDGKAVLPL
                     GTLSVEETKAPNGYLLDGAYMQAGDKSEQIKGLYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETSDTKPQGSATLKDTAFDVISLNDNSVLVEGKLYKKNEVVKTIR
                     TDIEGVASTSADLLPYGKFRIVESEAPDGYLTDGAKPIDFAITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSAEWTSHK
                     HNTNAGKTSEDGVWFGTSEADDSKGALPYDTYIIEEMRCDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDSEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFIADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDRQTVLITERIIKIHTTATDKDGNKEIEAGKDVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENAELLINGKRVESDYTFTADSETMKAEVAFTLDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDEGQTITFNEKPEVPEKPETPQTPEKPN
                     RPSDSPKTGDSTNVMAFLVMLLTSAGGLAGTYLYKRRTMKKS"
     gene            44022..44348
                     /locus_tag="KRL22_001383"
     CDS             44022..44348
                     /locus_tag="KRL22_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1271884.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPIFERDKNNRKVIARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDVGHTDYVLVADDI
                     VAVEEK"
     gene            44364..44747
                     /locus_tag="KRL22_001384"
     CDS             44364..44747
                     /locus_tag="KRL22_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1271885.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNTGTSQNHTPQGQPKK"
     gene            44849..45286
                     /locus_tag="KRL22_001385"
     CDS             44849..45286
                     /locus_tag="KRL22_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271886.1"
                     /translation="MCEECYSDENRITPLLNPLDCLENHTQYICGTCGRCICIEHDPN
                     RGLQRWNFPFKSLEIAKLYLRTADYTTKSSCGIYEIENSKGRVSYKIFAGNEDLHLFL
                     KKNKDKKCKQMTPVFNVGEYKEYPHTEVRKLTSDEIKQYMSER"
     gene            45380..46774
                     /locus_tag="KRL22_001386"
     CDS             45380..46774
                     /locus_tag="KRL22_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1271887.1"
                     /translation="MRMILNKGHRIRASDKNLVYRFSMGTLLFVFVAVILLLNTKQLM
                     RTDWEHFSLLDNGFTLSLYNFITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSVFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEQMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVGLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAQARQ
                     DGTATCEAKGDGTD"
     gene            46958..48154
                     /locus_tag="KRL22_001387"
     CDS             46958..48154
                     /locus_tag="KRL22_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1271888.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVVSGITREYLNKIESGK
                     MKPSKELLETLNKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDV
                     LIDGGIMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKYYQSGELIKHREDDR
                     EYMGSTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFIDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEKQAILSEKHEMIIKQQTTPA
                     KDLVES"
     gene            48167..>48244
                     /locus_tag="KRL22_001388"
     CDS             48167..>48244
                     /locus_tag="KRL22_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH1271889.1"
                     /translation="MWELVKDFLLVSMGMGIGVVLMCILS"
BASE COUNT        18103 a         6508 c         9939 g        13694 t
ORIGIN      
        1 ccgaaaaact ctattataca gctctgattg gatatatctt ctatgaagct ccaagggaag
       61 aaaagaactt tgcaacactc cttgatatga tagacgcttc agaagttaga gaagatgatg
      121 aaacatatat gaatcctatt gataggttat ttgaagcatt ggaaaagaaa gaacctacgc
      181 actttgcagt aaagcaatat aaaaaataca aacttgctgc cggaaaaaca gcgaaatcta
      241 ttcttatctc ttgtggtgca aggcttgctc catttgatat tagggaactt agggacttga
      301 tgggggaaga tgaacttgag cttgatacac tcggagatag aaaaacggca ctctttgtta
      361 ttatctctga tacagatgat acctttaact ttgtagtgtc tattatgtat tcgcagttat
      421 ttaatctctt atgtgataag gcagatgatg tatatggcgg acgattacct gtccatgtga
      481 ggtgtctact tgatgagttc gctaatatcg gcttaattcc taagtttgag aagttaattg
      541 caacaatccg ttcaagagag atttcagcaa gtataatact tcaagcacaa tctcagttaa
      601 aagcaatcta caaagataat gcagatacaa ttgtaggtaa ttgtgatagc accttgtttc
      661 ttggcgggaa ggaaaagact acattaaaag agctttctga aacacttgga aaggaaacga
      721 tagaccttta caatacctcg gaaacaagaa gcaatcaaaa gagctttgga ttgaattatc
      781 aaaagacagg aaaggagcta atgagccaag atgagataac agtaatggac ggtggaaaat
      841 gtatatttca gcttagaggt gttcgacctt ttctatcaga taaatacgat attacaaagc
      901 ataagaatta caagctcctt gaggactatg acaagaggaa tttgtttgat atagagagct
      961 acattaagcg taaagggaaa gtgaaaatga atagacatac tgtaattaca agattgtaac
     1021 atttttctta tcactatatg tagatgtata aatttggtat aatgttgttt aaataaatga
     1081 tattttatgt atgaaaccta taatatttgt actaatactg tggggtagga aaagaaaact
     1141 tcctatatac taaaatcaac cgaaagaaag gaggaaatta gaatgaatat tatcaagtca
     1201 tttaacagta caattgatta tcttgaaaca gttcttgatg atgaaattga tgaaaagaaa
     1261 gtaactagaa tatccggata ttcttattcg atgttcagtc gcttgttttc tattctaact
     1321 gaaatgacac tttcagaata tttaagaagc agaagattaa cggaagctgc gattatatta
     1381 agagatacag atgaaaaaat tattgatgtt gcattcaaat ttggatatga gtcatcagat
     1441 tcgtttggga ctgcttttaa gaattttcat ggatttactc cttctgaggt gagaattgga
     1501 aaaccgttta aattagtttc cagggtgcaa ttagcattaa gtgtaagagg aggaagaagt
     1561 atgaatataa ggattcaaaa gaaaaaagca tttacagttg caggtgtaaa tcaacaaaac
     1621 atcaattcat caatatgtgc aagcctatgg caaaaactat tttcaaaggt atctcatgaa
     1681 gaaatgttaa acttagggac cggagaagtt gtaggagtat gccatgatat attaagtctt
     1741 gataatcatg atgttttaga tagtaacacg ataaattata tggcaggata tattgttaca
     1801 gatgtagata aggcaagaag tatgggacta gatattttag aaattggaga aacagagtat
     1861 gcggttgtag agttaacagg tagtgttcca gagtgtattc ataacggttg gaagtatgcg
     1921 atggaagtgt tctttcccga gcatggatat gttcattcag gaaagccgga ctttgaatat
     1981 tattatgaag gagatatgta tagtaaagac tacaaaatgg aactttggat tcctgtatgt
     2041 aaatcttaac aaatttcagt ctatagtttt aaaacaaaat atataaaata caaggtgata
     2101 gaaagtaaaa gctatcgcct tttttatgta aaaatttaag gagatagaat gataaggata
     2161 agaagtccta cttaaaggaa aatcaaatag caagagtata agcgattggc aaagtatgaa
     2221 gtccggtcgc ttttttaaaa gaaaaggaga agttttaatg aagcaagaaa tgattaatat
     2281 taatgccaac ttgttggcag aaccgacttt ctcaaaattt gaaaaagagg gagaaaaagt
     2341 ggaagttgca aacttcacgc ttgtaaaaaa gtatgggaag ggcaaggaat atatcaattg
     2401 tgcagcctat ggtgaaaagg cgaaaacagt aaaagccttt gaaaaaggcg atttgatcca
     2461 tatctttggt tactttaaga agcgtgaaaa agacggaaag acttacaaaa actttgttgt
     2521 aaagtcatat aacaagattg aaaagaaaga agaaaacgag gaggaataaa tcatggaatt
     2581 ttttacacag gcggtaaatg tattaaagat tttagttatg gcagtaggtg caggacttgg
     2641 agcatggggc gttattaacc tgatggaagg ttatggtaat gacaatccgg gtgcaaaaag
     2701 tcaaggaatc aagcaactta tggctggagg tggcatagta cttatcggat taaagctgat
     2761 tccacttctt gcaaatgtac tcagataaga agaaaaggag aaactaaatg tttgggatat
     2821 tcgacaaaat agaggagttt ttcaaagagt ttctattagg cggtatccaa gcaaacttag
     2881 agtctatgtt tcttgacatc aacgataaag ttggtgcgat tgcaacggat gtaggaaaga
     2941 caccgatggg gtggaacgga caggtcttca gttttattaa aagcattaac gattccgtta
     3001 tcatccccat agcggggcta atcataacgg cagtcctttg tatcgagctt atcaatatgg
     3061 ttatgcaaaa gaacaatatg cacgatacag atacgtttga tttttttaaa tacatcataa
     3121 agatgtggat tgccgtatgg ttagtatctc atgcctttga gttttcaatg gcagtttttg
     3181 atgtagctca gcatatggtt aataaagcag caggagttat aaacacatca gcaactgttt
     3241 ccggaaatca gattgtagca atgattgatt ctctaaaaga caaaggtctt ggagagcttg
     3301 tgatgatact ctttgaaacc tctctcataa aggtagctat acaggttatt tccattgtga
     3361 taatgcttgt ggtttatgga agaatgtttg agatttatat ttactcatcg gtttcagcca
     3421 ttccatttgc cacaatggga aacaaagagt ggggacagat tggaacaaac tatatcaaag
     3481 gattgtttgc cataggttta caaggactct ttttaatggt ttgtcttgga atatacgcag
     3541 tattagttaa gacaataaag ataacagaca tacacacaag tacctttacg atacttggat
     3601 atgcggtttt gctagggtta atgatgttaa agagcggaac actggccaaa agcgtattaa
     3661 atgcacacta aaagaaagga agggtaatat gaacaaaaga aaaacagtat ttatagtagt
     3721 aattggagca ggtattatgg cggtgataga taggatcaga cttcacagca aggtaaatga
     3781 cttggaagaa agaaaaaaag acatcggtcg ctgccacaat gatttttgcc taatgcagga
     3841 aagatttaac agaagtatag atgaacagat tacaagtatt caggaagaaa tcggctccgt
     3901 atatgagcat atcgaggagc tttcaaaggg aaaagaagat gggaggtaag ttatggcgta
     3961 tgtacctatc cccaaagact taaagaagtt aaaaacaaag gtggcattta acttgacgaa
     4021 aagacaactg ataggtttta cgattgcagg acttattgga atacctatct atttatttat
     4081 gcgaaaggtc gttcctaatg atatagcagt catatttctc attgtgtcca ctctccctat
     4141 atttttcatc actctttttg aaaaggacgg attgacattt gaaaaatatt ttaaatatat
     4201 ttaccttcat aagttttatc agccacaaaa aagagtgaga aaggaggttt accttgaaca
     4261 aaaaaagaaa gattcagcag ctaaagttag aacaaaacaa aaagaagtta agaagtcaaa
     4321 gacaggactt aaagcaaaat aagggaaaat ctaaaaaaga taaaggcggg ctacttgacc
     4381 ctatctttag gaaagaacca aaaagatata ctgttgaaga taccattccc taccttagac
     4441 tattaaaaag tgggatatgt cagattgatg aaaatcattt taataagagt atcgcctttg
     4501 aggatataaa ctatcagctt gctttagaag aagataggga tttgattttt aatcagtttg
     4561 caaactttct taattccttt gatccaagta taagcataga gttttcatat atcaatcagc
     4621 ttggcagaaa tgaagaaatg aaatcggcaa ttcaaatacc ggataaagga gatggttttg
     4681 acgatatacg tcttgagttt cgagaaatgc ttaaaagcca gattgtaaaa ggaaataacg
     4741 gactgaaaaa atcaaaatat gtaactttta cagtagaagc ggataattta gaacaggcaa
     4801 catcaaaact ggaaagaatg gagatagata tattatcaag ctttaaaagt atgggagtaa
     4861 gagcagaaag ccttaacggg gaggaaaggc taaagatact tcatgatgtt ttaaatccga
     4921 ataagacctt tgaattttca tataaggact taaagaaaaa ggaaagtaca aagacatata
     4981 ttgctccaga tgaatttaac tttacaccgt caaggtattt taagtttgga aattttatcg
     5041 gagcagcaag tcattttcaa attcttgcaa gtgagctttc agatcgtatg ctgtcagagt
     5101 ttttggatat agatgataac atcaatatct cttttcatat caaggcaatt gagcagtcag
     5161 aagccatcaa gatggtcaaa agaaaaaata ccgatattga caagatgaag attgaggaaa
     5221 acaaaaaggc tgtaaggtca gggtatgaca tggacattct tccaagtgat ttaattacct
     5281 atggggaaga tgtgaaaagc ctattaaaag acttacagac aagagatgag agaatgtttg
     5341 ttgtaaccat catttttatg aactttgcaa ggacaattca aaagctggat aacaccattt
     5401 ctcaaattag ctccattgcc aataagcata attgcaagtt aaaaaggctt gaccactcac
     5461 aggagcaggg cttaatcagt gtacttcctc ttggggtaaa taagattgaa attgatagag
     5521 ggctaacctc atcatctacg gcggtcttta tgccgtttac cacagaggag cttttcataa
     5581 actcggcaaa cagtttgtac tatggactaa atgccctaag tcataacctg attatggcag
     5641 atagaaagaa gttaaaaaac ccgaacggtc taatccttgg aactccggga agtggtaaat
     5701 cctttagtgc aaaaagagaa atggcaaatg ccattcttac aaccgatgac gatgtgatta
     5761 tctgtgatcc ggaaggcgaa tacggaaacc ttgtaagaca atttaaggga gaagtcataa
     5821 aggtcagcag taagtcgaag gactatctca atcctttaga tataaatatg aactatggag
     5881 atggtgacgc accactaaag gacaaagcaa acttcattat gtctatgctt gagcttgttg
     5941 taggaggtag tggtcttaca gcagaagaaa agtcggttat agatagatgt ctgcctaaga
     6001 tttatggaaa gtattttgaa aatccaattc ttgagaatat gcctattctt caagacctgt
     6061 atgatatgtt aaaaaatcag gaagaaaaag taggtaaaaa gttggcaaca gaaatggaga
     6121 tttatgtaac aggatctctt aatgtattta ataacaggtc aaatgtggac ttaaataagc
     6181 agcttctttg ttttgatatt aaggagttag gctcgcagct taaaaaaatt ggaatgcttg
     6241 ttattcagga tcaggtgtgg aacaaggtat cgcaaaacag aggaaataag gctacaaggt
     6301 attatataga cgagtttcac ctattgttaa aagacgagca gacaacttcc tattccgtag
     6361 agatttggaa aagatttcgt aagtggggtg gaatcccgac aggcattaca caaaatgtca
     6421 aagacttact tatgagtaat gaaattgaaa atatctttga taatacggac tttgttttaa
     6481 tgcttaatca ggcttcaggc gatagagaaa ttttagcaag gaaacttaaa atctctcagc
     6541 cacagctaaa atatgtaact aattccaatg caggagaagg acttttgttc tttggaaaca
     6601 ccattgttcc tttccttgat aagttcccaa aagacacaat actttatcag aagatgacaa
     6661 ccaagcctga agaagtgagg taggcttatg ggaaagaaac tgaaaaagga ctttaaggaa
     6721 aggcaaaggg caaggattga aaaggaaacg ctgcaaagta atatgggaat tgagcctgaa
     6781 gaaagtaagt taaagtataa cgatgattac agagggaaaa ttgttcatga taaagacaga
     6841 ttccaagata aggtgcatga gaaaacaagc aaaatgacct ctgacagtga accagttaga
     6901 gggacttcca aaagaaatgc aagatataga gcttccaata aggatagcat aacttcttca
     6961 actgaaactg gaggtgtaag tcaggaagaa atcgggaaag cggattatgg tacggaggtt
     7021 aaggatggaa aaatctatga tcctttagga aaagaccttg ataatgacgg aatcatagat
     7081 agatatgaca atgattttag ggacagcgac tattttgagt caacctatga tgtagatgga
     7141 ttaaaaaaag atgagattag cggaaatccg gtaaataagc aaaacactca aaagaaaaat
     7201 tataagagaa aaaactattc cgataagctc tatacaagaa agaaggacaa agaagctaaa
     7261 gaggaaaaag cagataataa aaaaagcgga aaagaagctg ttcttgatag agaaaagaaa
     7321 aacaggcttt ctaaagaaca ggaaacaatt ttcgagaata agacttctaa agtatctgct
     7381 ttatcaggct tagcaaaagg aagcgaaacc gtaagagatt atttatctca tggaagtgat
     7441 gaaaatcaag gggtagaggc aggagaaaag acagcagata caagctcaaa actcattcat
     7501 ggcattaaga actactagga taagaaaaga acaaagaaag gatatgacct tacaaataag
     7561 gactataaaa tcagaaagcg aaaatccaaa ttagagtttc gagatgccaa agaggaactg
     7621 aaaaagacgg aggagtatca aaaagcaaat aactttaaac gatttcaaaa aagaaagcag
     7681 atgaaagatt ccattaaaag gcagaataag tcaaggctta gagatcgcat taaggaaggg
     7741 cttatcggca gtcttaaaag ttcaaaggaa gttatattaa gaaaaacgaa gggacttatg
     7801 attattttca taggtcttat tcttttggga actttcttta ttaactttgc agggacagga
     7861 atgacaggct ttatgaactc tacaagtaca gttcttacaa caagttattt atcaaagcct
     7921 aatgttctca cagaaattca tcaacaattt tctagtatgg agcaaggatt acaagatgag
     7981 cttgaaagtg ttgaagaaaa ttatcccggt tatgatgagt atattgtcaa taaagaggga
     8041 gatattggtc ataataccca tgagctttta tcctacatta catcaaggtt cggagaagta
     8101 aagaatgtat cagaagtaag ctctgtatta gatgagcttt ttaagtccat gtataggctt
     8161 gagtataagg aagaaattga aatcagatac aggacagtta cagaaatcta tactgatgaa
     8221 gatggaaacg aatataccga aagccatgaa gaaccttatg agtacaagaa actcattgta
     8281 actctttata aaagagaaat ggatagtgtt gttcgagaag tgtttcaaaa ttatccagat
     8341 aatgtaaaac attatgaagc attacttgca agtcttggta atatgagtga cttttttgga
     8401 agtggaagta atgattattc tgaaataata aacaatccta attttggcaa tccgggaata
     8461 gctttcaatg aagaaacggt taaacgactt ttctcagaag cagaaagaca tataggaaag
     8521 aggtatgttt ttggtgcaaa tgggccgtca aattttgact gctcttcatt tgtgtgttgg
     8581 agctttactc attcaggtat taaaaatatg ccaagaacaa cagcttggag aatttatacg
     8641 gattactgta atcctgtaag tacaggtgaa gccaaggcag gagatataat attctttaaa
     8701 aatacctata atagtggaag cccgatttct catgtaggta tatatgccgg aaatgggatg
     8761 atgatacacg caggggatcc tattcaatat acttctatta actcaccata ttggagagaa
     8821 catttttatg ggtttggaag accaagatag gaggatacaa tttgaaaaaa gaactgacag
     8881 cagtaaaaaa tagaataaag aaattgaaag ataaaaaggc tctgattgat gaagaattgg
     8941 agcctttgtt cattcgtgaa gaagaacttg aaaacgaaga aattattgcc atttgcagaa
     9001 aaaataacat tacaatttct gatcttatgg caaaagtaaa cagagaaaaa tcagaaatga
     9061 aaaaggagaa cggaaatgaa aaaaatgaag aataaaaagg ctgcgggagt aattcttgga
     9121 gcagtgcttt tgatagtggg agtagtaatc tctttatttg caggtagtaa gattgtattt
     9181 gcacaaggag ggttgtttac gacacttgta aatccgatag aagccgttgc tcaaatagaa
     9241 gtagaagtta atgttaagta tatttttgaa gatgaaaaag tctttaagga ggaaaagatt
     9301 aaggctgaaa aggagtggct tcttgacagt ggagatcttc caataattcc tgatgatatg
     9361 aaatttatag atgaatttct attttatgaa gtaaagggag acgggaaaga tgaaattatc
     9421 cgtaaagtta caaagattga tgttaaggat aaggaaacgc aaacagaaaa tgaaagctca
     9481 aaatctgagc aaagctctca atcaaatgct tcaaagatag aaaataaggg aactcaaaca
     9541 gagcttagca aagatgatat ttctaaaatg gaaagggagt ctaaggaact taaagaaaaa
     9601 cttgataagc taaatcagga gattaaggac aaggataaac taagcgagaa gcaaaaggat
     9661 aaaatcaaag accttgagga gaaaatagat aaactgaagg aaaaacttga aaagggcaaa
     9721 gatgataagg acttatcagc agatatgaaa aaggagatag acaagctaac cgataagatt
     9781 aaggaacttg agaaaaaggc taatgaggtc ggtagagctc ctattatgca taatcctaat
     9841 gtaacaccaa ttagccctat ttccggaatt aaacaaggaa caggaaatgt atcaccacaa
     9901 acatctataa atagcagtgg taaaggttct gccacgcagg aaagtaaagg ggcaaataca
     9961 aaagatacaa acagcaatga atcaaaggag aaagaaaagc aagttcgtta tccaaataag
    10021 ctgacaccaa aacagcctgc taataatggt agtcacgatt cttctctgga tggttcaagt
    10081 aagaatataa ataccaacaa aggagttgct tcagaacctt caaaggcacg aggaacagtt
    10141 actgaaaata aggataatgc aaacaaaaat tatcctattc accataatga cagtaaagat
    10201 aataaagaaa cggataaata ttctgctgat gcaagacagt ttgttacctt tacaactaaa
    10261 aatggtaaga cctttcattt aatcattaac catgatgagg atagcgagaa tgttatgctc
    10321 ctaactgaag tatctgaaga tgatctctta aatatggtag aaaagaaagc accggagaaa
    10381 gagattgtta aagaagaatc acaaaaagaa gagcctaaac aagtgaaaaa agaagaaagc
    10441 agtaatacag gaacctactt aattctcatt cttgtagtag cgggagcctt aggtgcagga
    10501 tattatttta aggttattaa gaaaaaagaa gataaggagc ttgaaggctt tgaggaggaa
    10561 gatgatgatt tcttttcaga ggcagaagaa agcgaaaatg aagtaaacga agcagtaaca
    10621 gaagataaag aagatgatga gatagagtaa acttgtcccc aaaattatat aatatttggg
    10681 gcaaaacaca gggcgagaga gtaaaatctt tcgccctctt atattgaaaa caggaggaaa
    10741 actatatgaa acttgtaata gcagaaaagc caagtgttgc aatttctatt gctaaagtaa
    10801 ttggagcaac aaaaaagaaa gacggatatt atgagggaaa cggatacaag gtaagttggt
    10861 gtgttggaca cttaattcag atggcaaatc cggaaagtta cgatgaaaag tacgctaaat
    10921 ggaatatggc ggatttaccg attattccaa gagaatataa gtatgagatt gcaaagtcca
    10981 caaagaaaca atttacgatt cttaaaaagt tgatgaatga caaggaaata gacattgtga
    11041 taaatgcttg cgatgcagga cgtgaaggag aagcaatctt caggcttgtc tataatcagg
    11101 caaattgcaa aaagaagatg aaacgccttt ggatttcatc aatggaagat agtgcaatta
    11161 aagagggctt tgataaccta aaagacggaa gtttttacga taatctcttt gaatctgcac
    11221 aagcaagagc gattgcggat tggcttgtgg gaatgaattt aagtaggcta tactcgtgcc
    11281 tatataagca gaattattct gttggcagag tacaaacacc aactcttgcc atgattgtaa
    11341 aaagagatga tgaaatagca aatttcaaga aagaaaaata ttttacagta gagcttgatt
    11401 tagacggctt ttctctttct accgatagaa ttgatgataa gacagttaca gagcagctta
    11461 tcaatctatt aggtaattcc atagaaatta ccgatgttat tcaaaaggaa aagataacaa
    11521 aacctgagct gccatttgac cttacaacgc ttcaaagaga gtgtaataag tatttaaatt
    11581 atagtgcaaa gcagacctta gattatacac aaagtttata cgagaaaaaa ctgattacct
    11641 atccaagaac ggacagtcgt tatcttacag aagatatgat tacaagtaca atcaacaata
    11701 ttattggaaa gcatgatttt gatacaggtc gcattaagat ggtatttaat tctaaaaggg
    11761 ttacagacca tcatgcgatt ataccgacag caagcagtat gaatgaggac ttagcttcac
    11821 ttccggaaag tgaattgaag gtatatgaac ttgttttaaa taagctacat gcaagtgtag
    11881 gctatccttt aattgagaat actacaaaga ttgtagctgt atttgacgga tttgaattta
    11941 caagcagtgg aaaggtgatt gtagatgagg gctttaccaa atacctaaaa aaatatataa
    12001 aaaagaaaaa tgaagatacc gtgtttccgg atttaaagat tggtgatagt cttgatatta
    12061 aggagaaaga gataaaagaa aaatacacat caccggctaa acattttacg gaagatacac
    12121 ttttaaagga tatggagctt gcaggaaatg acgcactgga aaaaggtgta gaagttgagc
    12181 gaaaaggact tggaacacct gcaacaagag caggcattat tgaaaattta atctttaagg
    12241 gttttgtaga aagagataag aaaaacctta ttgctacaca caaaggaata agccttgtaa
    12301 cgattgtctc agatactttt aaatcagcag gtacaaccgc taagtgggaa atggagttat
    12361 cggatattgc acaaggcaaa gcttcaaagg aaaatttttt aaaagcgatt gaaaacgaga
    12421 taaaagaatt ggtttcaact tatagcaagt aagatagcac taattttaat atcgaaaaaa
    12481 tgtcctaaaa atgctataat ttttgtaggg aaagtaggaa atatggaggt gttttatgtc
    12541 ggaagtattt atgaataatg caaaggttat ggcaaaggga caggttacta ttccaaagaa
    12601 aataagagaa atattagaaa tcgagaatgg agattatgta acttttgttg taactgaagg
    12661 gaaaatacaa attgttaatt caaaaacttt tatagagaaa aatatacagg gcaggaaata
    12721 aattatagat ggcagatgca gataggagga atttatgaat aaagaaaaga attctttaca
    12781 aaatataaac atagaaaaaa acaacaattc atttgaagaa attgttatga ttgtagaaaa
    12841 tgcaaaggat cgtgcatata gaaaagttaa tgaagagcta atcttaatgt atcaagaggt
    12901 tgggaaatat attagtgaaa aaacaaagga agcatcttat ggttcaggat tcgtagataa
    12961 tgtagctgaa tttttttcta ttaactatcc tgatttaaaa ggatttaatc gcagaggcct
    13021 ttatagaatg aagcaatttt acgaactgta caaagatgat gaaaaagtgt caacgctgtt
    13081 gacacaattg agttggtcta atcatttaaa aataatgtcg ggagctaaaa gtagagaaga
    13141 gagagaattt tatattaact tagcaattaa ggaaaatttg acacatcgag agctggtaag
    13201 acagatggat agtggatact atgaacgctg tatgctttca aatgagggaa atatgcctgc
    13261 aatacaaaga gcgaaacagg aaacacataa tttgtttatg gatagctatg tattagaatt
    13321 tcttgatgct cctaaaattg gaaatgaaag agaatttcag aagtcaattc ttgaaaattt
    13381 gaagaacttt gttttagaaa ttggaaaaga tttttctttt ataggtaatg agtatagagt
    13441 gcaggttgga aatcatgact actatattga tttattattt taccatagag gtttatcctg
    13501 cttggttgct tttgaactta aaatcggaga atttaagccg gaatatgttg gtaaaatgaa
    13561 cctatatcta gaagctttag atagagaagt taagaaacaa gcggaaaacc caagtgttgg
    13621 agttattctt tgtgcatcaa aagatgatga agtagttgag tttgcactaa gcagaagcct
    13681 ttcgccaaca atggtatctg aatatagatt aaaattgata gataaagaac tattacaaag
    13741 aaagttaaaa gagtatacag gaattgcaga gcaggagata gaaagacatg atgaaaaata
    13801 gataaatata actttgtgca tcaaaaaatg agtgaagtag tccatgtgga aacaataata
    13861 aaataaaagt gtttcaattt agtaatatac tatgaaagga tatgaaaaga aatgcgtaca
    13921 ggcaatgaat ttaacggtgt tgaggatact ttatatatac ctttagctgc cagaatatat
    13981 gtatctgaaa aattcccaca ttttttctat gatgaaaagg ctctatcttt gaaacccaag
    14041 attccaacag gcggtataga taacaatagt acggaatatt tttatatggc tagtgtttgt
    14101 agacaacaga ccatagatat gaaaattaaa aaattccttg atgaaaataa aaagggaaat
    14161 atggtattct taggagcagg tttagagact tcatataatc gcataggaaa tcaaattgta
    14221 aatttctatc aagtagatct tccgggtgta atagaagtac gaaaaagagt gcttggaaat
    14281 gctaaaaatg agaaacttat atcaggagat atgtttgacc ttaactggat taaagaaata
    14341 gatacttcat tgccgacact tatttctgta gcgggtgtat atcagtattt tgacgaatat
    14401 aaaattatag atatgattca aaaattgaaa gctcaatttt ctaagggaga attgatattt
    14461 gacgcaacaa actctaaagg tttgaagctt gctaataaat atgtgaagaa aacaggaaat
    14521 aaaaatgcac aaatgtattt tagtgttgat aattctaaag atttagcaga taagactgga
    14581 acaatactat tggaagttga tggatttttt catggagcat tgaaggcttg tcagggatta
    14641 aaactaatga cgaggttata tatgtatttt gcagataagt tgcatcgaac attggttata
    14701 catttgaggt ttaattaaat tctattcaat tagttcttat tacttgtatt caacgtataa
    14761 tatatagaat caaaaggtgg ttagagaaaa tctaattgcc ttttttattt gtaaaaaaga
    14821 aggaggaaat atgcgaataa atgattttca taacattttg gagcttgtaa aacaggatat
    14881 tctgcaaagt gaagcagaat atctgaagct cttaaaggtt gtcggaaaca atcagagata
    14941 tgactttaga agtcaactta gtatctacga taaaaatcct gaagccacag cctgtgccaa
    15001 gttcgactac tggagagaac gctttaaccg aacagtaatg cgaggtcaaa agggtatccc
    15061 tattttagag gactacggca catacaaaaa agttgactat atctttgata taagccagac
    15121 agtttcaaag aatagggatg tcaacgaggt taatctttgg agatttgata aggaagctca
    15181 caaagatgta ttaaaagaaa tgataaaaac tgaaggctat gaagaaagcg aaagcacctt
    15241 agaaaatatc ttttctttaa gcaggctcta cggagatgaa aaaatagata acctgatgaa
    15301 tgagcttaga atagctgacg aggatagaat ttcctttact aaatttgtga gggattcgat
    15361 aagctatgca gtagcttcaa gatttaagtt agactatcct atggataagg agctgttaaa
    15421 ggaaaacttt gcaatgcttg acagcatttc tcttatgagc cttggagaaa cggtgtcgga
    15481 tattagcgga acagttattg atacgactat tcaaaaaagc aaagagttag agcttaaaaa
    15541 agaagtttta agaggtaaag aagcaggata taataaaata aaagaagaat tagaggaggt
    15601 agaagaaaat gtacttcgac gagatgatca ggaaagaatt agtgaaaacg agcgaatttt
    15661 ccgaaatgga aagtacgggc gagataatag agaaaatcaa ggagaataca ctgaatcagt
    15721 tagaggaaga gatggacttt atgagggaat atccgaatcc agtgtacgca gtgatgaggc
    15781 tgaattatct ttcaaacagc gaagagcaga gccacttcga gatgttagtg gatctataca
    15841 aggagaagaa gctgaccaaa cacctgatgg atactcagaa acaggtgata gagtttatga
    15901 gagccgaaaa gcaaaaactg atgatgtctt ggcagataga gaacgagagc catcctcagt
    15961 acaaagcaat gatttcagcc ctcaaagaaa tgacaatcaa ggaagtagtg gaaatctaaa
    16021 agagaatacg gataaagaga taagggaagc tgataaggct tctttttcct tgcctgaaaa
    16081 cagctcagga caaattaaac ttacaatacc tcttgcccaa aatgatattg acagcattct
    16141 tgtaaacggt ggaaaccatg agggtggcag acttcctatc attgctgaat tttccaaagg
    16201 aaaaacagta gaaaaattag gagaatacct taaagatacc atgggaggcg gaaacggttt
    16261 cttccttaat ggaactgaag tatcttcctg gtattcggat aaaggcattc atttagccta
    16321 cggaacttcc gcaagagaag atatgacgca aattttaagc tggagtgatg ctgcaagaag
    16381 aatcaatgag cttttggaaa atggagagtt tgctacaaat gtagagcttt tagaagcaca
    16441 ggactatgaa agaaatagaa tttcagaatc gctatggtat ctatatcacg atttaagcga
    16501 agaagggaaa gcacagggct attttgactt tatagaaaca ggtggtggct ttccgaaaga
    16561 aacaagacag ttatcggaag ctcttaaaaa tcctgactat ctaaaagatg ttgtttccga
    16621 gtacagtcgc tttttgacag gatataaaga aaacaaagag gtactaagat ttcactatca
    16681 caaagtagat agcctttacc agagattaca ggagcttgca cttacaagaa aggaatatac
    16741 ctctaacctt atcgaacttc caaagataca gggctttatt acagaagatg aagtccttgc
    16801 tacaatttca agaggaagtg gagtcgataa aggaaaagag cgaattacta agtttttcaa
    16861 agaaaatcat accttgcagg aaaaagcgaa tttcctaaaa ggtgaatatg ggatcggtgg
    16921 aggctctcat gctgtatcag gcgaaagagg aagcggagaa tggcatgatg caaagggact
    16981 gaaattacag aagaatcatt gtaacgatgt ttttcttaca tggtcaaatg tagcaaagca
    17041 tatagatgag ctgctttcta agaatcttta tcttgaagaa aagaacattg aaaaaaaggt
    17101 agagatagaa gaacaaaaag agccaagtta ttactctaaa gacgatccat ataatctaat
    17161 tactgatgaa atgcttgaaa aagttcctga actttatgca caagaggatg tagctttagc
    17221 agacaaacag gttcatgcag catacatcat tccatttaga agtaactgga cttggtatat
    17281 gacggaatat gacagggaaa gtaaagatgc ttttggactt gttttaggaa ttgagccgga
    17341 atggggatat tttaaccttg atgagctaaa ggaattaaat gcccagaggc ttgttttaga
    17401 agattttcca aagaccttta gagaacttaa agacagtgaa cttaaaaagc agatggatga
    17461 gcaggagctt tatcaagttt ttaacggaga gctaagtttt gaggaaaata atatagaact
    17521 tgaagcacct gaagatgtag aagaaagcaa acaagcagaa ccttttcagg ctactttatt
    17581 tgactatcta aaggaaaaag aagaagtaga gcttaacgaa aaagagaaca gcctttcaga
    17641 tgagtttaca gttaaagaag gcgataccgt ctattttaat catgaggagt acaaagtaag
    17701 agatctttct aaaaatcaaa tcacaggaaa aaatgatttg tggcttgatc ctgtaaggca
    17761 aggtaatcat caaatcccta ttgtagcttt tacagataat gaggatttat taagacaaat
    17821 aagtcttgaa agacctgaat ttatcatcgg tgatgaagtt aagtacaagg gaaaagacta
    17881 tgccatcaca aaatttgata atatgggaaa taacctaaag actgtaacgg ttaaggataa
    17941 taccgaatat cttggaggta tgattacagg ctccgatgta attccttatc gccaagaaag
    18001 tgagcttaat aaaatttttg aaaatttgac ctataaaaaa gaggagcttt atgaccttgc
    18061 agtaagaata gatgagatag cttatgattt tgattcttat gactatgcgg attccgtaga
    18121 agcagaatca gagaaaagac ttgataatat caaccaaatc tatggtgatt tacaagcagg
    18181 aaatgtttca gtatatataa atagtttgaa tgagatgatt gaagaagatg ttgaagatac
    18241 ggaaatcatc aagcaagtat taacacaatt agaagaaaaa aagattgata ttcagcctaa
    18301 acaagaagta ttcaatttca agattacaga agaaacactt cctcaaaggt tatctccaag
    18361 tgagaggtta aataataacc ttgaagcaat ctctatgctt aacagagtgg aaagtggaga
    18421 acgagagctt gatattacag ctcaggaagt tttagctaaa tatgtcggct ggggtggact
    18481 ttctgatgtc tttgatgaaa gcaaggatgg acagtggaaa gatgcaagag ccttcttaaa
    18541 ggaaaatcta tcgtcatcag aatatgaagc tgcaagagaa tcaaccctaa cgagctttta
    18601 tacaccgaaa atagttatag atggaatata taagactctt tccggtatgg gatttaaaca
    18661 aggtaatatc cttgaaccgt caatgggtat cggaaacttt atcggtaatg tacctgatga
    18721 aatgggtaag tcaaagtttt atggagtaga gcttgactcg gtaagtggtc gcattggaaa
    18781 actactgtat ccggaaagtg aagtacaggt aaagggactt gaagaaacgg gattctccaa
    18841 taacttcttt gatgtagcaa tcggaaatgt cccatttgga gagtacaagg taaatgacag
    18901 agaatacaat cgcaataact ttcttattca cgattatttc tttgccaagt ccattgataa
    18961 ggttcgtaac ggcggtgtta tcacctttat tacatcatct ggaacaatgg ataaaaagga
    19021 cgaaagtgta agaaggtatc ttgcagcaag agctgaattt ttaggagcaa tcagacttcc
    19081 aaatgatacc tttaagggtg ttgccggaac tgaggtaaca agcgatatta tattcctaaa
    19141 gaaaagagat agcgtattag agcgagatga agcttggata cacctttcag aagataaaaa
    19201 cgggcttgta tataacaaat attttgtcga tcatcctgag caggtgcttg gttctatgcg
    19261 tgaagtaagc ggaaggtttg gaaaaactct aacctgtgaa ccgatagctt atttagggca
    19321 agagataaat atggcttcat taaaggagcg tatcgagatt gcaggagaaa gaatttcaaa
    19381 agataccaag tatgaagaaa tagagctttt agatgatgaa atcacttcaa tccctgcaac
    19441 cgatgatgta aagaacttct cttatacctt gaatgatgat gaagtctatt acagagaaaa
    19501 ttcgctcttt attaaaaagg aagtatcaga caagaataaa gaaaaaatca aagattatct
    19561 tgagctgaat gttgccttaa aagatgtgat ttacaagcag aaggaagatt ttagcgaaga
    19621 agaaatcaag gcttcacagg aaaaactaaa tgaagtatat gacaactttt caaagaagca
    19681 tggctttgtc aataatttaa gtaataccag agctttgaaa gaggatagca actttccact
    19741 tgtttcctcc atagaaattc ttgatgaaga agaaaatttc aaggcaaagg gagatatttt
    19801 ctccaaaaga actattacaa aagccaaagt tatagaccat gtggatactt ctttggaagc
    19861 ccttgtttta tcggtatctg aaaaaggcta tgtggacttt gactatatgg gaagtcttac
    19921 aggaaaagac agagcgactt taattgagga gcttcgaggg gaaatctact taaatatcag
    19981 agaagaacaa aatttttaca gatcactttc ttttaatcct gaagatggag atttaccttt
    20041 tgcctgtgca aatggcagta attcctataa atatggctat gtaacaaaag atgaatacct
    20101 aagtgggaat atcagggata agattgccat tgtagatagc tatttatcaa agttaagaca
    20161 aacggaacga gagcttcctc atcttggctt tgttgagaat ggaaaagaaa aagagctgat
    20221 aagctatgaa atgaatcgtt tggaatatca aaaagcagag cttaccaaag ttcttccaaa
    20281 ggaattagaa gcaagtgaaa tcaatgtgcg tcttggtgcg acttggatac cgattaaaga
    20341 tattgaaaaa ttcatctttg aaactttaaa aactccggga tatgcaagat gggatattaa
    20401 ggttaaattt tcaaatatta caagtgaatg gaatgtagag ggaaaaagca gggataaagg
    20461 aaatgacctt gcagaaatga cctttggtac atcaagggta aatgcctata agctgattga
    20521 agatgcccta aatcttaaag aaacaaaggt atttgaccag attataaatc cggacggttc
    20581 taaaacttct gtcttaaata aaaaagaaac catgcttgca ggacaaaagc aggagctatt
    20641 aaaagaagaa tttaagaact ggatatttaa cgatcaggaa agaagaaacc gtcttgtaaa
    20701 actgtataat gagcgtttta actcaatccg aaacagagaa tatgatggaa gcaatctttc
    20761 ttttgaggga atgaatacag aaattgattt aagacctcat caaagaaatg ccatagcaag
    20821 aagtctttat ggaggaaaca cattgcttgc tcatgtggta ggcagtggaa agacctttga
    20881 gatggtagct tccgcaatgg aaagtaaaag acttggaatg tgcagtaagt ctttgtttgt
    20941 tgttccaaat cacttaacag ggcaaatcgg tcgtgaattt atgcagctat atccgtcggc
    21001 taatattatg gtggctgata aaaaagactt tgaaccgaag aacagaaaga gatttatcgg
    21061 aaagattgcc acaggggaat atgatgcggt tgttatcggg catacgcagt ttgaaaaaat
    21121 cccgatgagt aaggaatatc aggaaaagca catccaagat cagattaatg aaatcgtaaa
    21181 ctatgtagaa gaatacaagc atgacagaaa tcagaacttt acagtaaaac agcttgaaaa
    21241 gacaaagaaa aaactggaaa cgaggcttga gaaattaaat gatgatttta agaaagacga
    21301 tgtaattacc tttgaggaac tgggagttga tatgctcttt gttgacgagg cacataatta
    21361 caagaacctt tatctctata ccaaaatgag aaatgttgca ggtatcgggc agtcagaagc
    21421 ctttaagtcc tccgatatgt ttatgaaatg cagatatatg gatgaaatga caggaggaaa
    21481 aggcatagtt tttgccacag gaacacctgt aagtaactca atgacagagc tttatacaat
    21541 gcaaaggtat cttcagtatg agagtttaaa gaaaaatcac ttagagcatt ttgattcttg
    21601 ggcttccact tttggagaaa cacaaagctc ctttgaacta tctcctgaag gaacaggata
    21661 tagggtaaaa acgagatttt caaagttcta taacttgcct gaactaatga gtatgttcaa
    21721 ggaagtagca gatattcaga ctgcggatat gcttaacctt cctacacctg aagctaatta
    21781 tgaagttatt aaaactgagc cttctgaaga acaaaaggaa atcctaaaga gcctttctga
    21841 aagagcggat gatgtcagaa atagggttgt agagccggat gttgataata tgcttaagat
    21901 taccaatgac ggtaagaaac ttgccttaga tcagcgttta atcaatcccc tacttcctga
    21961 taaccctgat agtaaagtaa atgtatgtgt aaaaaatgta tttgctattt gggataagac
    22021 aaaagaaaat aggtcaacac agctactttt ctccgatatg tctactccaa aaggagatgg
    22081 agaatttaat atctatgatg atattagaga aaaacttgta gcaatgggaa taccgaaaga
    22141 agaaatcgcc tttatccatg aagcgaattc tgataagcaa aaggatgaac tctttgcaaa
    22201 ggtaagaaaa ggcgaagttc gtatcttaat gggttcaacg cagaagatgg gagccggaac
    22261 gaatgtgcaa aataaactga ttgcacttca tgatttggat gtgccttgga gaccagctga
    22321 ccttgaacaa agagctggta gaattgtaag acagggaaac gaaaatgaga aagtaaatat
    22381 ttatcgttat gttacagaga atacctttga tgcgtacctt tggcagacga tagaaaataa
    22441 gcagaagttc atttcacaga ttatgaccag taagactccc gtcagagttg cagaagatgt
    22501 ggacgaaagc tcccttaact atgcagagat taaagcactt gccactggtg atccaaaaat
    22561 caaggaaaag atggacttgg ataacgaggt tacgaaactt aaaatgcttg aagcaaacta
    22621 taagtccaac cgttacagat tagaggataa agtggcgaaa aactatcctg aagaaatcgc
    22681 aagaacggaa aaactcatag aagctgttaa gaaagatata gcaagtgtag aacctaaagc
    22741 ggaaggtgag gaaaagttta cttccattac cattgcggga gaaaagatta acgataagaa
    22801 attagctgga gaaagactgc ttgaagctat ttccaaagtg aaaatcaatg aaagcaaggt
    22861 gataggcaag tatagaaata tggatttaga ggtaagctat aacttcttta ccaatgaaca
    22921 taattttagc ctaaacggtg ctgcaaagca ttcaggagag cttggaacaa gtgcggacgg
    22981 taacattaca agactggata atgctcttga gaaaatgcct gagaaattaa ataggcttga
    23041 agaaaaactt atcagcacaa aggaacaact tcaaaatgcc aaagaagaat taaagaaacc
    23101 ttttgagaag gcagatgagc tgaaaactaa ggtgttaaga cttgcagaac tgaataagct
    23161 ccttgatatg ggagaagtgg aagaaaagag aaatgataat ccacttgtag aagatgtaaa
    23221 aatggcaatc attgatttct gtaacagaga gtacgaagaa aatcatagct atgatgaatt
    23281 taataccttg tatcctgact taaagcatat cggtatcgcc tataccaata caccggatga
    23341 aaggcatggt attcagtatg agcttgattt agaggagaaa acttggacac agtatattga
    23401 tggtacgcca atcaagacag agagctttta ttatgagaat aaaggagaaa atgaagctct
    23461 taggaatatg aaaaatgaga ttgagctatt ctctttcaat gatttggtct atgtagattc
    23521 agaggacttg aaagctgctc ttggacttga tattgatgat gagggtaact tctatgatcc
    23581 gctttctaaa gaccttgata atgatggtat tgctgatagg tacgacaatg actttagaga
    23641 cagcgattat tttgagtcca cttatgatgt ggaggataac ttaaatacaa aagtggaatc
    23701 tgtaacgaaa gcagaggata agccgtctat tttaagtcag atacgagctt atcaaaatga
    23761 aagtaaaaca gaagaaaaac aaaaaacaaa agaacaggaa attttaagat aaggggaggg
    23821 caacctccct tttgccatga aaggagataa aaacatggat tacaaaacaa tgataaatca
    23881 aatagaagat atggtaaatt ataaccataa ggactttgta aaggcgatta taagcatgga
    23941 aaaaggtatc aatgatgaaa gtgctttaga caagctctat gacgcttata tggacaatga
    24001 cagccttaat ttactgcatg aggaatttga ctatatgatt gaggatttaa gggaacaggg
    24061 acagataaaa gacctgcctt atgttcagga agaaaaggat aatcttatca atattgttgg
    24121 aaatatcgtt ggagaggttg atgtagtaga aagggaaaac aagaatggag aagcctttaa
    24181 ggtggcgaat ttctccgtag tatccaaaga cgatgagggg aataaggtat atcataattg
    24241 ctccgcttat gggggaaaaa gcgatattcc aaaggacttt aagcagggag attttgttaa
    24301 gctctttgga caaataagaa catctattga tgataacggc aaggaacata ggaatatcag
    24361 aatactttct tcaaaactgt taaaggaaaa ggaacaaatg aaaggacaag aagaaaagaa
    24421 agaatctgta cttggagcta ttaagaagta tcaggctgaa gataaggaaa agccaaaaga
    24481 aaagaaagag gcaaaccaag aagctgagag ataaatttat ggtcggtgtg gtcttaggac
    24541 tgcaccgact ctttttttat ttgcacgagt tcgattaaag agaatatatt tatgaaaaaa
    24601 gtatatttta tggtataata tactaaatat agttttcttg agcggaggat aagaatgagg
    24661 gcttttagtt ataaaagatt gttcaaaaaa ctcattgatt tagatatgac aaataatgaa
    24721 ttgatggaaa aggcaaaagt gagtaaaagt acattttata aaatgaaaaa cgggcagaat
    24781 gtaactacgg atgttttgct taggatatgt aacgctttgg attgtgatat tgaggaaatc
    24841 gtggagtgca taagaattga taaatagatt ttgaaaggag gttaagtatg tctaaagaaa
    24901 agtactacat gaacttacca aaagatttat ctggaagcat tgctaaaaat cgctttagat
    24961 tagaattatt atggggaatc agtaagataa tcgatgaaca taaagcgaac aatgaatata
    25021 cgataatttt tgattttaaa tgtgatatag aattgcataa agaggatgaa ttggattttt
    25081 atcaaatcaa gacgaaaaaa agtggtaatt acaattcgaa taatttgtgt aagaaaggta
    25141 agaataagaa caattctatt ttagggaaac tatatgcttt atattcaccg aactacaata
    25201 taaaattagc aattgtgtgt aataaacaac ttaaaatcaa taataaagaa attgattttc
    25261 ctgagcaatg ttttggagat ttagatcagg atgtacttga tgatgttagg aaaaagttgt
    25321 gtacagaatt aaatttagac actgtatgtt tagataatgt gttttatata tttgataaca
    25381 tggatttatt aaatccagag gattctatta gagggaaatt agtaaaatct tttgttgata
    25441 ttaaaggtga agaacctcaa aatccgaatg cattgtatag actggttgtt gattctgtta
    25501 aagaaaaggc ttcttatgaa tttgattccg gtacttatga agatgttgta aaaaacaaag
    25561 gtattacaag aagtgaattt gataaaatgt taaatgcaca taaaaaggaa tctaaaaatg
    25621 gaatcaatga aacacaggag tatataaata acttgtcatt tgctaaacga agaagataca
    25681 atacggcact tggtaatata cttgaaacac agcaaagtga gtctttacga ttaataaaaa
    25741 taaaaattta taattatatt gtggaacatg aaaattcgtt agacgatatt gaaagttatt
    25801 taaaagaaat atcaaaatta tttgatgacg attttgatgt ggaatttact gatgatatga
    25861 aatcggttca atacataatg atttattata tgtatgcttc aggaggaatt ttataatgaa
    25921 tgttatattt gacaaaatat atatatttga tgttgtaaaa aaaaaggctt attcaacaga
    25981 atttaaaaaa ggagttaata ttattacatc gagtgatata gacggaacag atagaggaaa
    26041 atcagtttta ttaagaagtt tataccatgc cttgggtgcg gattctcact ttgactcgaa
    26101 gtggggagaa aaggataagg tctatatctt attttttaag gtggatgata aagatttttc
    26161 gatttataga tctcaaaaat tatttaaaat atttaatgca aaaggtgatc ttatttttac
    26221 tactattcat agaagtgaat tagcagattt ttttggaaat ttatttaatt tttctatatg
    26281 tttgccacaa aaaaatacaa atcaattagt aatagcacca cctgcatata gttttttgct
    26341 gaatttttta gatcaagatg aatacatcgg tacaaaattt aattcgttta aaaaccttgc
    26401 tcagttcagt aattttaaac ttaatgttat ttactcacat ttgggcattt acaataaaga
    26461 atatttcgaa cttgtgaaac acaaagaaga attagaactt gaaattaaaa gtaagaaaga
    26521 agaaatagaa gacctaatta aaatgaaaga cagaaccatt ttaattttgg atggtttttc
    26581 atgtccggaa acaagcagtg cattagaaaa tgagcttaat atagaaactc aaaaatattc
    26641 atcgctaatt aatgagatga atttagtaag gaataagctt gttgacttga gaaatcaatt
    26701 agttgaacag aatatcactt tatctcaaat atctaaattc gaaataaaag aagaaaagga
    26761 aataaaaact attttaaaat caaaagtttg tcctgaatgt cattctgttt tagattcaac
    26821 tttggaacta aggagtaaga gatataatca tattgataat gctcttagtc tgaaagatgc
    26881 aataaaaaca gaaaatgccc atattgaaga tgaaatactc aaaaatgagg gaatatattc
    26941 aaacttaact ttggttttgg aggagcataa taaaaaaatt tgtaaaaaca aaaaggaaat
    27001 caaagactat atcaagttca gaggactaaa taaactaatc gatgagatta ataatgattt
    27061 gactattaat agcagagtta tagacagtac aaaggaggct ctaaagccac taaagaaaga
    27121 atttaaaagt gttaaagata aaattaaatc tgttgatgaa aattactatt atttgattga
    27181 taaattaaaa ataagattca atttaaatga gttagaagct gacagttatg aacaactatc
    27241 taaaaatttt tgtgcaagtg gaagcaacaa accattatca accgttatat ggtatctaac
    27301 actcaatgat ttaaaacaga aatttaatcc tgaaggaaca acatttccaa tggtttttga
    27361 tagccctaac aatgcggaga cagatcaaga gaagaagcag gcattagtcg agtatattat
    27421 ggaatcatca gatcaattta gccagttaat tgtttcggca ataggatttt cagaaaaaga
    27481 ttatagcatt gattcgaata taaatataaa agttttagaa aatgaaaaat atagcttact
    27541 aaatagtgag atgtatgttc agaattatga gcttttacaa tgtatgaacg atgcttaata
    27601 tagcaggggt taattaggag atggctatct ctccatctcc ttatccatat aaattccata
    27661 gttctttcgt atttgataaa gctcgtccat agtagatttt gtagaagaat actcttgcat
    27721 tagggtattc tttttttctt gcaatttatc aagtttatct aaaatgccct ttgaatcagg
    27781 aagctttgaa taggactttt taagttttgc aagagccgtt tcatagcgtg tgatttcagc
    27841 cttatgctcc tcaaaaaatg ccttatcgga tggatttgct ttatattcca tgtagtattg
    27901 cttgtatttt ttaacggtat gaactttttc catagtggta gaaagctcct gcatttcttt
    27961 atcaataatc tttattttat cctgtaaatt ttgtctttcg tcggctactt tttggatgta
    28021 ctcatcaagc tgtttaacgg atttaatgcc atgttctctg atataaatta cagactcagc
    28081 cattgtatta aggttatgtt tggttgccca atattcgtat cctttgcttt cctttacttt
    28141 cacattggta ttcatgtcaa taacattgcc gattcgtttt ttgacaggtg gggttttaat
    28201 cgtttgattt tctgtaatac gctcttttaa tctttcttct gtatagtcct caccaatcgt
    28261 cttagctctt gtaaatctct gtttgtcttt tggcttaaag gctatatgtt ttccatactt
    28321 tatttcataa ccaagctccg ccattttctt tagaaattct tcccaatcct tagactgttt
    28381 tatcagacga tcaatgtcaa attgaagttt gcttttccaa gaagtacctt tcttagattg
    28441 ctcattttca taccatgact taccatttgt tttgtacttt ctcttatagc tctcgtagaa
    28501 cttatcaatc acagaaaggt tattttcttt gcatagctta tcgctttgat acctgatttg
    28561 gtggtagctt ttcttgttgg aatgatagca ttttcctgtt accatattta cattattgaa
    28621 gataatatgg ttgtggatat gccctttatc tatgtgggta gataagacaa attcgtattc
    28681 gtcctttaat atctttttac atagctccat accgatttga tgtgccattt caggacttgc
    28741 ttctccgggt aaaaaggatt gaataaggtg tcttgcaaga acggttccgt ttgttccgac
    28801 atcatttcgt gttcttaaaa attgggtatg agcagtttcc tgatggcatt tatgagtgct
    28861 tactaagatt tgctcatctg ttttttctcc attaacgata tatgaaatgg cgagattaag
    28921 ggttgatttt ataggatgta tttttgtaat agccataaga tttaatcacc tccggaagtt
    28981 ctgttaagga gcagggaatg aatttgccat agctcttttg agaaatgttc aatctcattt
    29041 tttatatcat ttatgtcatc tttatagata acaccagtgg aatttacacg ctttgcaatc
    29101 tgattgatgt tgtttgttgc attggaaagt aagccttgta aatctcggaa aggctctaaa
    29161 tctacctgat aaatttcctt ttccaaaacg catttgcgga taaagtggct catatttctg
    29221 caccttgcga gctttcgttt ctcctcaaaa agagcctttt cttcttcagt tagtttaatt
    29281 tccagtcttt catttcgtat tctatttgcc ataggtaaat cctcctttga atgtatttcg
    29341 gggtcttagg gtatacccta acaagttaaa aattgataaa aaaagaagca tatcccagag
    29401 ggctgcttca tcaatttttt cgtaagtgtc cgtacactta ctgtgcttgc tcatatacta
    29461 atcgtgtaag aacaacttta agcataatac ttatattatt ataccatagt ttggaaaaat
    29521 aaaaaattat atttcatcaa cgtttcataa aaggtgtgta gaatgttatt gaaagtagct
    29581 ataaaatgct attgtgtaaa aaataaagga ggaataattt atgaaaaaaa tagtatcaag
    29641 aggagcatgc ctattacttg cattatgttt gagcttaaac gcagttgggt gtcaaaaaag
    29701 taatgaaaac aataaaatta aagaaggaca atccataagt tctgaagagg caggcatgtc
    29761 aattaatgca aatggcaaaa atgaaacttt taagccatca gattatacat tggaggcaaa
    29821 gaaagaatat gtttatgaat atttagggct taaatttaaa ctctcagaca aatttagaaa
    29881 ttatatagct gataaaaaga tagcgatgtt agatgatcaa agtcctatag ataaagaact
    29941 aaagtatgct attttgacat ttgaaaaaat gacagaagaa caaaagaatg cagttataga
    30001 aaagatgggc gatggatata aaaattggca aaatgagctt gaaagaattg ggactattgg
    30061 tatattcgaa aaaaatacat cagaagaaaa aatatctaaa attacaaaat gtgatactca
    30121 tactaaaata ggagtttcaa gtgatggaaa atacgattgc tatttaagca caaatagcgg
    30181 agctgaaagt aatcttctgg atgaattaaa aagaactgag attcaaatta tagataaaaa
    30241 agaacgtcct aaaaatggtt ttgtgctatc agaaaaaact gatttagaaa atacagaagc
    30301 atttaacaaa gaatcggtta aagatttacg taaactatca acaaaggaca taaatggcaa
    30361 ggattttaca agtaaagatt ttgagaagta tgatcttact atggtaaatg tatttgcaac
    30421 ttggtgtaca gcttgtgtaa aggaaattcc tgatttggtt gaggttcaga atgaaatgaa
    30481 aagcaagggt gtaaatatcg ttggagttgt tacagatact gttgatgata acggtgaaaa
    30541 caaggaagca attgaaaagt caaagttaat acatgaaaag acaaaggctt catatccttt
    30601 cttaatgcca gataagacaa actttaatgg tagattgaat ggtatacagg ctatgccaga
    30661 gactttcttt gttgatagta atggaaatat tgtaggtgat acttattctg gggcaaagag
    30721 tgcaaaggaa tggaagcagg taattgaaaa agaattggaa aaaataaaaa ataaataaaa
    30781 aataaataaa agtaaagcgg tgattggtat atggttaata agtttttaaa aagccgtgcc
    30841 ttgtctttat taattatctt tattagtatg gcgatgattt actatggtca tagtaatgga
    30901 gaaactaaag ttgtcttgga taaggcgata agaatttgta tggagtgtat tggaattgga
    30961 tagaattaaa aatattataa atggtagtac aaaaaaagat aaatataaaa taagagatcg
    31021 ttttaggcat ttacttcaat ccgtttggtt tttaattact aattcttact ttgaagggtt
    31081 taagactggt aaaatctacg gtgggaattt aaagaaaatt tgtgttccag gtatgaattg
    31141 ttattcatgc ccgggagcaa aaggttcttg tccaatagga tcactacagg cagtaattgg
    31201 aaattcaaaa tataagatta gttattatat agttgggatt ttgtttttta taggagcatt
    31261 ggtgggaaga tttgtttgtg gatggctgtg tccatttgga ttgattcaag atttgctaca
    31321 caagattccc ttttttaaaa aagttgaaac atttaagttt gataaacatt tgagaaaatt
    31381 gaaatacata atattacttg tatttgtaat aatattacct ttatttttgg ttgatatttt
    31441 aggtcagggt tctccgtatt tttgtaaact tatttgtccg attggtatgc tggaaggagg
    31501 attaccactt gttttattaa ataaaagtat gagaagtgcg ataggtttct tgtattattg
    31561 gaaaggaatc attctaatag ttactttgtt actttctata attatgtata gacctttttg
    31621 taaatatata tgtccacttg gagctattta ctcaattttt aaccctattt caatatttag
    31681 atatagattg gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat
    31741 gaatatagat ccagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa
    31801 aaatgcttgt ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag
    31861 gaaagtgata aaaaatgcta tagcatatat tacaagaaag agaaatagaa ctttaataat
    31921 ttttatcata ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc
    31981 aagcaatgaa atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa
    32041 aaaagatggt aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat
    32101 tgaagaaaaa ataattcaat atgatggatt agcaaaacta aaagatgcta aagtagttag
    32161 cggagaacaa agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact
    32221 tgaagctaca aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa
    32281 agaaggtaaa aatataggag aaaatgataa gaattcaatt attgttcatg aagaatttgc
    32341 taaacaaaac aatctaaaat taggtgatga agttgatctt gaattactag atattgaaaa
    32401 aagtggaaaa ataaaaagtc ataaatttaa aattataggg atcttttctg gtaaaaaaca
    32461 ggaaatatat acaggattat cttctgattt tagtgaaaat atcgtgtttg tagattattc
    32521 aacaagccaa gagatattaa ataaatcaga aaataataaa atcgcaaata aaattttaat
    32581 gtattctggc agtgcagaat ctacagactt agccttaaac aaattgaaag agcttaaaat
    32641 tgatgagtca aagtattttg ttgaaaaaga ttctaatgcg tttgaagagt ctttagagtc
    32701 agtgagtgga ataaaacata taataaaaat aatgacttat tctattatgt taggtgggat
    32761 ggttgttctt tcattaatct tgattctatg gttaagagaa agaatttatg aaataggtat
    32821 atttttatct attggaacat ctaagataca aattataatg caatttatat tcgagttaat
    32881 attcatatcg ataccaagta taatatcttc cttattttta ggaaatgtat tactaaaagt
    32941 aattgtagat ggattcatta actcagagga ctcaatgatt tccggtggaa gtttaataaa
    33001 taatagtagt tttatgttaa atataacaac acttggacaa agttatttaa tattaataag
    33061 tattattgtt ttatcagttg tatttgcttc ttcattaata ttaatcaaga agcctaaaga
    33121 aatattatca aaaataagtt aggagaaaat aatggatata ttagaaataa agaatgtagc
    33181 atatagttat gcaaattcta aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact
    33241 tgggaagttt tatgcgatag taggaaagtc aggaacagga aaatctacac ttctttcctt
    33301 acttgctgga cttgataaac ctcaaacagg aaaaatattg tttaagaatg aagatataca
    33361 aaagaaagga tatagtaatc atagaaaaaa taatatatct ttagtatttc aaaactataa
    33421 tttaatagat tatttatcac caattgaaaa tattagatta gtaaataaat cagcagatga
    33481 aagtatcttg tttgaactag gtttagataa aaaacaaata aaaagaaatg ttatgaaatt
    33541 atctggtgga cagcaacaaa gggtagctat tgctagagca ttggtatcag atgctccaat
    33601 aatactagct gatgagccta ctggtaatct agacagtgtt actgctggag aaataattaa
    33661 tatattaaag acattagcta aagatagaaa taaatgtgta atagttgtaa cacatagtaa
    33721 ggaagtagca gattctgcgg atatcatttt agaactaagt ggtaaaaagt tgaaaaaagt
    33781 aaataaaatg aatttggagg ttgaataatg ataaaaaatg catttgctta tgtaactaga
    33841 aaaagcttaa aatcattaat tattatatta gttattttat ctatgtcaac tttaagtctc
    33901 attagtttat ctattaaaga tgctacggac agagcttcaa aagaaacatt tgataatata
    33961 acaaatagtt tttctatgga gataaataga caagtaaatc caggaacacc tagaggtggg
    34021 ggaaatgtaa aaggtgaaga tattaaaaag atatctcaaa cagatagtat agactcctat
    34081 gtaaaaagaa taaacagtgt tgcagattta gttgattatg atattattga aactcaagag
    34141 actcttgcga atcaatcacc tgaaagagcg aagaatttta aaagaacagt tatgttaact
    34201 ggggttaacg actcatcaaa agaaacaaaa tttgtatcag aagcatataa attagtagaa
    34261 ggaaagcatt tagaaaatga agataaaaat aaaatcttaa tgcataaaga tttagctgaa
    34321 aaaaataatc ttaaagttgg agataagata aaaataaaat ctaatttatt tgatgctgat
    34381 aatgagaaag gtgcagatga aacagtagaa gtagaaatta aaggtctatt cgatgggcat
    34441 aatagcggtg gagtaagtgc agcacaagaa ctatacgaaa atacattaat cactgatgtt
    34501 catacagctg ctaaagttta tggtaataca gaagatacag ctgtatacca agatgcaaca
    34561 ttctttgtaa aaggtgataa gaatcttgat agtgtaataa aagatcttgg gaaattagat
    34621 ataaattgga gagaatataa tttgattaaa agttcatcaa attaccctgc attacaacaa
    34681 tctatatcag gtatctactc aatttcaaat aaattatttg ttggctcatt aatatttgca
    34741 ggagttgtag tttcattatt attattctta tggatgaatg ctagaaagaa agaaatagca
    34801 gtattactat cattaggtat atcaaaatta gaaatctttg gtcaattcct aattgagatg
    34861 gtatttatat caatccccgc attcgttggt tcttatttct tagctcaata tacagctgat
    34921 aagcttggga ataatatatt gaataaggtt actggtgata tagctaaaca aatagctaga
    34981 caatctgcat ctagccaatt aggtggtggg gcagaagctg aaggatttaa caagacatta
    35041 tcaagtttag atataaatgt attacctaaa ttcataattt atgtagttat atttatgagt
    35101 ttagtacttc ttgtatcatt gattatttcc tcattcaata tattaagaag gaatccaaaa
    35161 gaattattaa ttgacaataa ttaaaatttt cggtgctttt tagcaccaaa aattttttgg
    35221 cttttaaata tcaaataata tgctgtataa tataagtgta taggcttaag tggaggtata
    35281 tatgaaaata ttaactgttg aagatgataa tatgataaga gagggaataa gtgaatatct
    35341 ttcagaattt ggatatactg ttattcaagc taaagatgga agagaagcct tgtcaaaatt
    35401 taatagcgat ataaatttgg ttatcttaga cattcagata ccttttataa atggtttaga
    35461 agtgttgaaa gaaattagaa agaaaagcaa tttaccaatt ctaatcttga ctgcatttag
    35521 tgatgaagaa tataaaattg atgcatttat taatttagta gacggatatg tagaaaagcc
    35581 attttcattg ccggtcttaa aggctagaat agattcttta attaagaaga attatggaca
    35641 tttagagaag tttgaatata aggatctatc ggttaatttt aatagctata cagctaaaat
    35701 aaatggtgaa gaaatagatg taaatgcaaa agaactagaa gtattaaaat gtttattgga
    35761 taataatgga caagtgttaa caagaatgca aattattgat tatgtatgga aagatagcga
    35821 agaaactcct tatgatcgag taatagatgt atatataaaa gaacttagaa aaaaattaca
    35881 attagactgt ataactacta taagaaatgt aggatataaa ttggagagaa aatgaaaaaa
    35941 ttaaagatat ttccaaaaat gttcatacaa atattttctg ttcttggaat aataattata
    36001 ttagttcatt cattagtttt ttttatcttt cctaaaacat atttggagac gagaaaagaa
    36061 aagattcata atatggcaaa tgaaatttct agtaatatga atggaaaaga aataaaatat
    36121 atagaacaaa ctttggagct ttattctaag agtagtgaaa taaaagcatt tataaaagaa
    36181 aaaaataata agaatgaaat acaaatcaaa gataatataa atgttaattt agaaagtgat
    36241 agtaattctt tgataattga agaaagagaa ataaagctta atgatggtaa aaaaacaaat
    36301 ctacaatttg tttctacagc tgatatgcaa aaagatgcga aagatttaag ccttaaattt
    36361 ttaccatatt ctttattaat atcaatttta ttttctgcta ttatttcttt aatttatgca
    36421 aaatcaataa aaaataatat acaagaaata aaaattgtta ctgataaaat gatgaaactt
    36481 gataaaaaaa cgcgtttaaa agttagctct aatgatgaag ttggagaatt aaaacaacaa
    36541 attaatgatt tgtattctac tttattaaga acaattgacg atttagaatt taaaaataaa
    36601 gaaattttaa aattagaaaa gttaaaatat gactttttta aaggtgcatc ccatgaactt
    36661 aaaactcctc ttgctagtct taaaataata ctggaaaaca tgaaatacaa tattggaaaa
    36721 tataaagaaa gagatattta tattaatgaa tgtattgaaa tcgttgatag tttaacaaaa
    36781 aatatttctc aaatattatc agttcattct atagaaaatt tgaataatga tgaagaatat
    36841 ttgaaaataa atgatacatt agaagacata ttaaaaaagt atgaaatatt agcaaatcaa
    36901 aagaaaataa ctgtcaataa ttatatatta gatgagaatg tttatatagg aaaaacagct
    36961 ttaaagatta ttctatctaa tttgattagt aatgcggtaa aatatactga tgtaaatggg
    37021 gtaattaata ttgggatagt taatgattgg ttatatatag agaattcata cggtaacaat
    37081 agaatttcga atatggataa aatatttgat gttaaatttg atttaaataa ggaaaatagt
    37141 aatggattag gtttatatat tgtaagtaat attctgaata attacaatat agaatataaa
    37201 gcattgcagg atgaagaatt ttttatcttt aaaattaaaa tattttctta aacaagatat
    37261 aattttgcaa tagttattga aaaatagaga cttattatta gccatggaag taaaggcttt
    37321 tttcttattg aaagtgaaca gaaaataatt gatacaagaa atcaggattt gaacacgcta
    37381 ataaaaatat tgttagtaaa actatatgag ttagtctttt cggatgcaga gattgtttaa
    37441 atatttgata gaatagaaac ttaaaaagtt taataaaact caattatata agtagtagat
    37501 gaatatgatg gttatttaga ttattgataa aatggaggaa ataaatatgg aagcatctaa
    37561 acgtttaatg ttagaaatat ttagaattca atatattcct cttttttata atatgtatag
    37621 tagatgattg tttcaggtgc gaattgaaac aatcaagttc atataaagaa atatttttat
    37681 tctttcattt cagaggactt cttatgccaa gatgcagaag tcctcctttt ttatctgaaa
    37741 aacaagcaga taaaaaagag atggaggaaa ctttatggca aaagagtatt atctttatat
    37801 cagaggacaa aaggtaaaag tcagtgaaga tatatatata gtctactggc gagaaaaaga
    37861 acacgagaag tatttagagc aggtggacag gaaaaaccac ttgctctttt tttcagcatt
    37921 ggatcatgac ggacacttta cagataatat tgttgatgaa agtgttgatg tagaaaagat
    37981 tgttgaaaca cagatgatga ttgaagcagt aagaagtgct ataacaaggc tcaatgcaga
    38041 agaaagagat attattgaac gcttgtattt caatgatgaa actgttcgtt cagtagcaaa
    38101 gctcaaaagt attacacatc cggctttaat caaaagaaga aacaaaattc ttgaaaagct
    38161 gaaaaaattt atcgaagaac tttaaaactt cggtaaccaa agggggcaaa ttttccttat
    38221 gtaaagtgaa ggggagtttg atctccttta ctttcttgag taggagatac gcctgcttat
    38281 ggcaaatagg aaaatgtaaa gaaaacagtc cctttcaaat attgctcttt gacaactgaa
    38341 tagaccaagg taggacttta tctacttact gagagttatg acctacgcca agacttttct
    38401 gctgatgaaa atcggttcaa atgaataccg gcataatgcc gaggttagaa gaaaatgagc
    38461 gatagatagg aatacataaa agataagcgt ggcagcttat ttcgatgatg taagtggtga
    38521 taatgatact tcaatagttt aagctgcctc gtctgaaaca aggggaggag gtgagattcc
    38581 tatgtagcag ccaatgcacc taccaatgtc ataaaactta gtaagaaaaa taatatttgg
    38641 ttataaagaa tttaaagtgg aggaggtgta ttagtggata atgactggaa tggattggct
    38701 gatttgatag caaatctgat tacaaaatat gctggagttt tagatttaga gaatcttcca
    38761 aatcctactc cagtaaaaaa tacagaggat aagaataaat ttgatatagc taaaagcacg
    38821 gattgagaaa gagaaataaa agtgctataa tatacttgag attaaagtcc aaacttttat
    38881 tggtaaaaat atataaatat ataataagga tattgaggtt aatgctatgt caaaagaaaa
    38941 aataaaagta tatctctata caagagtatc tacatccata cagatagatg gttattcttt
    39001 agaggcacaa aaatcaagaa tgaaggtttt tgctctctat aatgattatg agattgttgg
    39061 tgaatacgaa gatgcaggta agtctggaaa atctatagaa ggtagagttc agtttactcg
    39121 tatgatggaa gatataaaat ccggaaagga tggagtgtct ttcgttcttg tatttaaact
    39181 atcgagattt gcaagaaatg ctgctgatgt actttcgact ttacaaataa tgcaggattt
    39241 tggagtaaat cttatttgcg ttgaagatgg aattgattca tctaaagatg cgggtaaatt
    39301 gatgatttct gttttatcgg cagtggctga aatagaaagg gaaaacattc gtgtccaaac
    39361 aatggaaggt cgcattcaaa aggcaaaaga gggtaaatgg aatggtggat ttgctccgta
    39421 tggttatcaa cttattgatg ggaaattgat aataaatgag gaagaagcaa ttgcaataag
    39481 aactattttt gatcaatatg taaatacaag tattggagct aatggtcttt ctaaatattt
    39541 agaaaatcat ggtataagga aaataccaag acaaaatggg aaaaatccat tgtttgacgc
    39601 aggtcttata agaaaaatat taaagaatcc tgtgtataac gggaaaatag catttggaag
    39661 aagaacttta gaaaaagttc atggtacaag gaatgaatac agacaagtag agcaggacga
    39721 ttatttagta gcagaaggca ttcatcaagc aataatccca gatgagttgt ggcaggctgc
    39781 acaagttaaa ctgaaagcac aagctaaaaa gtatgaacat gtaaataagg gcaagaacat
    39841 gaggacacac ttattatcag gaatagtaaa gtgtccgata tgtggagctg gaatgtttgg
    39901 gaataaatct ataaaatata aaaaagatgg gacgaagtat aaagacttct attactatgg
    39961 ttgtaagcat agacttatga atagaggaca taaatgtacc tataataaac aaattagaga
    40021 agaattgtta gatgatgccg ttgctgaggt aataatcaag ttagtaagca accctaaatt
    40081 tgcatctatg atacaagaaa aaattaacat gaaggttgat acatctgcta ttgaaaatga
    40141 gatagataat taccaaaatg agctaagaaa aagtcattct acaaagtata agcttattga
    40201 ggaaatagat aatttagatg tagaggataa acattataag agaagaaaaa atgatttaga
    40261 tgataggctt tatcgtatgt acgataaaat tgaggaatta gaaagtcagt taatagaagc
    40321 taaagcaaaa aaagaaacga tagaggttga gaaacttact ggtgataaca tatataaagt
    40381 attgatttat tttgacaagc tttataaagt catgaacgat gttgaacgca ggcagttaat
    40441 agaagcactc atttcagaaa ttcaaattta tgaagaaaag cagcctaatg gacaatggct
    40501 aaaatccatt acttttaagc tacctatcat tgatgaagat cttaatataa gtttggaaaa
    40561 tgatgagcaa gttgagactt gtgtgttgct acaaagacga actatgtaga aatccttaat
    40621 tttaggcact tttttaagca tatagtcttt acgagcgagg gcgataaaat cagaaataaa
    40681 gagataaaaa actatatcaa tgtttcagta gttgttgata tagagtgtgg gaacacaaac
    40741 aattaaatat tagatttgag gggtacttgt aaaaagtatc ccttttcaat gtaagacgtt
    40801 caatattgag cgtctatttt tttacccaaa atgaaaggag catttagaat tatgaaaaag
    40861 atattgaaac gattgtgtac gggagtactt gcctttgcga ctgtcgttac tgctttaccg
    40921 agtaccgccg tccatgcaga aagcaagcaa tactggacgg aatcagagga acgtgtcggt
    40981 atcgtagaaa aagtaatgaa tgacggttcg attggttcta cctttaacga gggacatttg
    41041 actgttgagg gcgaggacgc ttactgtata gacatcaata cagattttaa gaatggctac
    41101 aagaccagag ctgacgcaag cacccgtatg agtgccgacc agatttcaga tgtggcgtta
    41161 tccttagagt atgtcaaaca gtatggcgaa gcacacaagg aattgaacta caagcaagtc
    41221 tatctgttgg aacaatgtgt tgtctggcag agattgagcg tacatcttgg ctggcaatgc
    41281 gacaacgtgc gagcttctta tgatgaaata ccaaaagcaa cgcaggacga agttttcgct
    41341 ggtgctaaag cctttgtgaa agaaaataaa ggacgctatg aatgtggcgg ttatatctac
    41401 tctggcgagg ggcaggaatt gggacaattc tgggcgaagt taaatgtcgg aaatgcaaaa
    41461 ctgcaaaaga cttccagtaa taccagcatt acagacggta acgggaatta ctcaatcgct
    41521 ggtgcgacct atggtgtctt ttctgataag gactgcacga aacagcttgc cacccttacg
    41581 actgataaaa acggaaatac agatgttgta gaggtaaaag caggtacagt ctatattagg
    41641 gaattatccg caccagcagg atataaagtt gatacaaccg tgtattcctt aaaagttgaa
    41701 gctggaaaga cagcgacctt gaacgtatca gatacaccaa aagtagcgga caccttgatt
    41761 gagcttttca agattgacat ggaaacgcag aaagacaatc cgcagggaaa cgcttcttta
    41821 gagggagcag agtttacatg gaagtattat gctggcttct ataacaaaga caatctccct
    41881 gccgaagcta ctcgtacatg ggttacaaag acaatcgctg aaacagacag cgacgggaca
    41941 actcactaca tcacaaaatt agcggacgct tacaaggtat ctggcgacag cttctatatg
    42001 caggacggca aagcggttct tcctttagga acactatctg ttgaggaaac aaaagctcca
    42061 aacggctact tgctggacgg tgcatatatg caggctggcg ataagtctga acagataaaa
    42121 ggcttatacc ttacacaaat tacagaggac ggcgaccttg ctgtattgac gggaagtaac
    42181 cagttttccg tatcagacaa ggttatccgt ggcggtgtga aaattcagaa aagagattta
    42241 gaaacgagcg ataccaaacc acaaggaagt gccactttga aagatactgc ttttgacgtc
    42301 atttccttaa atgacaattc tgttttggtt gagggcaagc tatataagaa aaatgaagtg
    42361 gtaaagacaa ttcgtacaga tattgagggt gtggcttcta cttctgctga ccttttacct
    42421 tatgggaaat tccgtatcgt tgagagtgaa gctcccgacg gttacttgac agacggtgcg
    42481 aagccgattg actttgcaat cacagagaat ggaaaaatcg tggacttaac cgacgaagcc
    42541 cactctatct acaatcagat taagcgtggg gatattgagg gagtgaaaat cggtgcaggc
    42601 acacacaagc gtcttgctga tgttcccttt aggatcacaa gcaagacgac gggagaaagt
    42661 catgttgtag ttactgatga taacgggcaa ttctccactt ctgctgaatg gacttctcat
    42721 aagcacaata ctaacgcagg caagaccagc gaggacggtg tgtggtttgg aacttctgaa
    42781 gcagacgaca gcaaaggtgc attgccttat gatacttaca tcattgaaga aatgcgttgc
    42841 gatagtaaca aaggctttga acttatccca ccttttgaaa tcgtggtatc aagaaataac
    42901 cttgtgattg atttagggac tttgactgat gaatacgaaa aagaaatctc tatccatacc
    42961 acagcgacca gcaaagacag cgaaaagact atccttgcag gaaaagaggt aacaatcgtc
    43021 gatactgtca aattagacgg gcttacaaaa ggtacaaaat atcagctcaa aggctggcag
    43081 atgttaaagg aagaaaatgc agagcttatc attgacggaa aacgtgtgga aaatgactat
    43141 acttttatcg ctgatgatga agaaatgaaa gtggaaattt cttatacatt caatgcgtcc
    43201 gagcttggcg gtaaaaatct ggtaacattc gaggaattat acgatttaag caatccagac
    43261 gaacccgtga aagttgcgga acacaaagac attgaggacg acagacaaac tgtattgatt
    43321 acagaacgta tcatcaagat acatacgact gctaccgaca aagacggcaa caaagagatt
    43381 gaagctggaa aagacgttac aatcattgat accgtaacct tagagggctt ggaagtcggt
    43441 acacagtaca aacttgtagg ctggcagatg ttgaaagaag aaaatgcaga acttcttatc
    43501 aatgggaaac gtgtggaaag tgattacacc tttaccgctg acagcgaaac tatgaaagcg
    43561 gaagttgcct ttacccttga cgctacttcc cttgacggca aacagcttgt aacttttgaa
    43621 gaattgtatg atttaagcaa tccagacgag ccgaagaaag ttaccgagca taaggatatt
    43681 gaggacgagg gacagacgat tacttttaat gaaaaaccag aagtcccaga gaaacccgaa
    43741 acaccgcaga caccagaaaa gccaaacaga cctagcgaca gtcctaaaac gggcgacagc
    43801 acaaatgtca tggcatttct tgtgatgttg cttacatctg ctggtggact ggctggaaca
    43861 tatctttaca aacgccgtac aatgaaaaaa tcataaggcg gtaacggtat gatgaaagaa
    43921 aaatcacgtt ctccgccgaa actgtcaaac ggcagacaag ccagaataaa aaattacaat
    43981 cataaactta tcaaatatag aaagaaacga ggtaaaacaa tatggaaatg aaatatgtcg
    44041 tgccagatat ggcacagtct tttggaactc ttgaatttgc aggcgaaagc gagcctatct
    44101 ttgaaaggga taaaaacaac cgcaaggtca tagccagacg aagctataac ctttattctg
    44161 acgtacagaa aggcgaaaat gttgtggtgg aaattcccgt gcaggctggc gaaaagcatt
    44221 tcaagtatga acagaaagta aaacttgtca atccgaagtt atacggcaga gggtacgcaa
    44281 tcggggatgt gggacatacc gattatgtat tagtagctga tgatattgta gcagttgaag
    44341 aaaagtaaag gagtgaagaa tttatgagat tatcaaatgg atttgtcatt gacaaagaga
    44401 aaacatttgg agaattaaaa tttacagcgg tgcgtgatgt gttcttgcaa aatgaggacg
    44461 ggacaccgag tacccagctt aaaaagcgta tctatgattt gaagtgcagt ctgcatggtg
    44521 gaattatccc cgtgtccgta ccgccagaag taccgttaag ggaatttcct tacaatgcag
    44581 tcgtggagct tgtcaatccc gtagccgata cggtatcacg aaaaacctat acgggtgcag
    44641 atgtggactg gtatgtaaag gcagaagata ttgtactgaa gaataaaggc aatcagaaca
    44701 caggcacttc acagaaccat acaccgcagg gacaaccgaa aaaatagact tgctgaatag
    44761 attttcgttg tagaggatat acggaactgt tataatatgg gtatgaagaa agcgacaaat
    44821 tagaatttga taaggagcga aaagaaaaat gtgtgaagaa tgttactctg atgaaaatag
    44881 aataacacca ttactaaatc ccttggactg cttagaaaac cacactcaat atatttgtgg
    44941 aacttgtgga cgttgcattt gtattgaaca tgacccaaac agaggattac aaagatggaa
    45001 ttttcctttt aagtcattgg aaattgcaaa actttattta cgaacagccg attatacaac
    45061 gaaaagttca tgtggtattt atgagataga gaacagtaaa ggcagagtat cttataaaat
    45121 attcgccggg aatgaggatt tacatctatt cttgaaaaag aataaagaca agaaatgcaa
    45181 acaaatgaca cctgtgttta atgttggaga gtataaagaa tatccacata cagaagtacg
    45241 aaaattgact tctgatgaaa taaaacaata tatgagtgaa cgttaaattc cagtttgaca
    45301 acttcatatc catgcacaca aagcagttag tctatacgat tgactgcttt tttcataccc
    45361 agaaaggagt gattgattta tgagaatgat tttaaacaaa ggacaccgta tcagagccag
    45421 cgataagaac cttgtctatc gcttttcaat ggggacactc ctgtttgtgt tcgtagcggt
    45481 tatcctgcta ttaaatacaa aacagctcat gcgtaccgac tgggaacatt tcagcttatt
    45541 agacaatggc tttacgcttt ccctttacaa cttcataacc atactgatag cgactggtgt
    45601 ttgtgcattg gtcgcttttc tgtattaccg cttctgttac gacagtttca aaaagctact
    45661 gcaccgtcaa aagctggcac gaatgatact ggaaaacaag tggtatgaag ctgataccgt
    45721 acaagacagc gtttttttta ctgacctgca aagcagatca agggaaaaaa tcgtctggtt
    45781 tccaaagatt tattatcaaa tggaaaaggg actgcttcat atccgctgtg aaattacgct
    45841 ggggaaatat caagaccagc ttttacggtt agaggataaa ttggaaagtg gcttgtattg
    45901 tgagctgacc gacaagaccc tgcatgacgg ctatatcgaa tataccctgc tttatgatat
    45961 gatagcgaac cgcattacca ttgatgaagt acgggcagag aacggctgtc ttagactgat
    46021 gaaaaatctt gtctgggaat atgacgcact ccctcacgct ctgattgctg gtgggactgg
    46081 tggcggtaaa acatattttc ttctgacgct cattgaagcc ctactgcata ccaacgctgt
    46141 cctttacatc ttagacccga aaaatgcgga cttagcagac ttgggaacag tcatgggaaa
    46201 cgtgtatcac accaaagaag aaatgataga ctgtgtcaat gctttttatg agggcatggt
    46261 acagcgaagc gagcaaatga aacgacaccc gaactataag acgggcgaaa attacgccta
    46321 tctgggactg ccaccctgct ttcttatctt tgatgaatat gtggcgtttt ttgaaatgct
    46381 ggggacaaaa gaaagtgtgg gcttacttag ccagttaaag aaaatcgtca tgttaggacg
    46441 acaagcaggt tatttcctta tcgttgcctg ccagcgtcca gacgcaaaat atttctcgga
    46501 cggtatcaga gataacttca atttccgtgt gggacttggg cgtatcagcg aattaggtta
    46561 cggtatgctg tttggttcag atgtgaaaaa gcagtttttt cagaagcgta tcaagggacg
    46621 tggctattgt gatgtgggaa caagcgttat aagtgaattt tatacgcctt tagtcccgaa
    46681 aggacatgat tttttacaga ctatcggctc tcttgcacaa gcaaggcagg acgggacggc
    46741 gacgtgcgaa gcgaaaggcg acggcacgga ctagccgttg ctggtgtggc gtaagccacg
    46801 ccagcagata aaacccctcg gtatctaaca gaggggtacg tttgcaaata gacaaaagac
    46861 aaaaaacata ggaaacataa ggcttctggc acggtttcct agcaaaaatc ggctgtgaag
    46921 tcgccttaaa aaacttcaca ctttacagat tgggggtatg gttctgaatg aagaacaatg
    46981 gataaaagaa ttacgggaga aacggattgc ttacggtatc tcacaaggca ggctggcggt
    47041 ggtttctggt atcacaagag aatatcttaa caagatagaa agcggaaaaa tgaagccgtc
    47101 aaaagaactt ctggaaactt tgaataagga actggcaagg ttcaatccag aagcaccgct
    47161 taccatgctg tttgattatg tgaaaattcg ttttcccacg ctggatatac agcacatcat
    47221 caaagatata ttaaaactga atatcaatta tatgctccat gaagattacg gacattacag
    47281 ttatacggag cattattcat taggggacat ctttatctat acgtcggctg acgaagaaaa
    47341 aggtgtcctt ttagagttaa agggtcgggg ttgcaggcag tttgaaagtt acctgctggc
    47401 acagcaaaga agctggtatg actttcttat ggacgtactc atagacggag gcattatgaa
    47461 gcgtatcgac cttgctatca acgaccatac gggcattttg gatattccag agcttgcgga
    47521 gaaatgcagg aaacgggaat atatcggaaa gtccagaagc tataagtatt accagtcggg
    47581 cgagcttatc aagcacagag aggacgacag agaatatatg gggagtaccc tttatcttgg
    47641 ttcgctgaaa tcagatgtgt atttctgtat ctatgaaaag gactatgagc agtatgtcaa
    47701 attaggtaca cctctggaag aagccgacat tatcaaccgt tttgagatac ggcttagaaa
    47761 tgaacgtgct tactatgcag tacgagattt gctgacctac tatgacgcag agcagaccgc
    47821 tttttctatc atcaaccagt atgtgcggtt tattgatgaa gaaccagaca agcggaaaaa
    47881 tgactggaaa ctcaatgacc gctgggcttg gtttattggc gataatcggc aaagtctgaa
    47941 actgacgaca aaaccagaac cttacacctt agaccgcaca ttgcgttggg tacaaagaca
    48001 ggtagcaccg accttgaaaa tgctgaaaaa gattgataag ggaaacggta cagactacat
    48061 ggaaacgatt gaaaagcagg caatcttgag tgaaaagcat gaaatgataa tcaaacagca
    48121 gacgacccct gcaaaagatt tggtggaaag ttaggagtga taaaaaatgt gggaattagt
    48181 aaaagacttc ctgctggtat ctatgggaat gggtatcggc gtagtcttga tgtgtatttt
    48241 gagt
//
LOCUS       DAEPUT010000022        47483 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.022, whole genome shotgun sequence.
ACCESSION   DAEPUT010000022 DAEPUT010000000
VERSION     DAEPUT010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47483
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.022"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            66..254
                     /locus_tag="KRL22_001389"
     CDS             66..254
                     /locus_tag="KRL22_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271890.1"
                     /translation="MGKKSEYTVTTVGEPNLDALGETLAKILTEKFGVLITHTYIENY
                     YVDKERGGDVDGAIESEL"
     gene            238..457
                     /locus_tag="KRL22_001390"
                     /pseudo
     CDS             238..457
                     /locus_tag="KRL22_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861754.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            557..874
                     /locus_tag="KRL22_001391"
     CDS             557..874
                     /locus_tag="KRL22_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271891.1"
                     /translation="MESLKIVKQYVEGQLNLSSLEIDKNKETYEILKNKSSRDMLDDI
                     NLNDALREVTVNERLKIFAESLLELLDTQIKIKESEESEDYKRLCMYLDEFGRDRPID
                     VQI"
     gene            960..1469
                     /locus_tag="KRL22_001392"
     CDS             960..1469
                     /locus_tag="KRL22_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBH1271892.1"
                     /translation="MSTLYELTTDLLEIEEGLTEITGNEAEKLEEIKEIIKQEIQNKN
                     TRIVSVIIDIDSDINSLDLEIKRMQELKKIKKNSLDRLKSNIKECMELLGIKKVETFL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNTIKDFIKKGHEVEGCRIEYGTT
                     LTIPKAKKE"
     gene            1479..2087
                     /locus_tag="KRL22_001393"
     CDS             1479..2087
                     /locus_tag="KRL22_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBH1271893.1"
                     /translation="METNNVYIKLVNIQSTLKAPKSQFNSFGKYNYRSCEDILEGLKP
                     ILKEEKALVVLDDNIVQIGNRFYVEATATLIDAETGEKVSTKALAREDETKKGMDLAQ
                     VTGSVSSYARKYALNGLFCIDDTKDSDATNKHGNEQKKKEVNESELNILYSLGESIEK
                     DKNRVDSEVYKKFGKLAVDLTKQEYEKVLNGYKSILEKQKQE"
     gene            2097..2978
                     /locus_tag="KRL22_001394"
     CDS             2097..2978
                     /locus_tag="KRL22_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBH1271894.1"
                     /translation="MGIIRVSKDKDNPYVVLNKTCLEDVKLSWQAKGLHSYLISKPDH
                     WKIYVNDLYKRSKNGRDATANILRELIENGYITRTPCRDSNTNKMLGGYDYQVYEIPL
                     ENPQKLKSRKTDFPETGFPGNRVSRKPENTEVVSNDFKVNNDITTIVINEQPQQDETT
                     YIKKYFEKYIGVITPNNFIELMSYLDDGMEADVIIRAIDEAISNGVKNYKYVKTILNN
                     WIEAGVKTNLELTEYQNEFERKKKSKQEKKQSNHKNVNTPNVSKNKFHNFNETFTQYS
                     PDELDDIIKKSQKVKFK"
     gene            3038..3418
                     /locus_tag="KRL22_001395"
     CDS             3038..3418
                     /locus_tag="KRL22_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271895.1"
                     /translation="MAKIWMDANEVLSKTMDLEDMFELNLRAIRKRNEKIKNEIEKQI
                     KYEDSEIKTTNRGGPGKIIKIFNINTGEVKILKSAEEASRYIKVSRSYASYLARENKS
                     TEDGWKAEYIQEVSDGISKCGTSN"
     gene            3524..3697
                     /locus_tag="KRL22_001396"
     CDS             3524..3697
                     /locus_tag="KRL22_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3797 domain-containing protein"
                     /protein_id="HBH1271896.1"
                     /translation="MKLKDIIKLGEKYCYCPNCGNDKIGNNEGKLIVEEHTYYRECSC
                     GFNVLIDDRKDEI"
     gene            3816..3974
                     /locus_tag="KRL22_001397"
     CDS             3816..3974
                     /locus_tag="KRL22_001397"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271897.1"
                     /translation="MDDRLEICKKMFPIITKNTRLLCHYCDGRNICSYDEEKAQELLR
                     NEEGTKNN"
     gene            4026..4301
                     /locus_tag="KRL22_001398"
     CDS             4026..4301
                     /locus_tag="KRL22_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271898.1"
                     /translation="MEYKEYEDLKNRVESYEDLQGSAEFAGRVIENLEDVDCPIRIGF
                     KFPSKEDYKNIELDIAAKDSNSIFIRTELAKAFKEILSKYEMDMENM"
     gene            4400..5095
                     /locus_tag="KRL22_001399"
     CDS             4400..5095
                     /locus_tag="KRL22_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271899.1"
                     /translation="MDLNKIMNDALVEIEESGFVEETVKKELEETIKRAVNEIFGSYS
                     KFRKNIEQHLGENININLDELDIQKYNLLVANVVKEKVDATMKGQGIEHLKRNLDNML
                     VGLKKEYKMSELLEELKEDKYNLDEYPCDEDCITFILESNFNSEWARWIDFDECPNVS
                     RNNCEHSILLRNDGTIAAFRYQNREISSKDIMNGFGNFGDLLFKIYAHNSKIILDLGN
                     DVDDYDLTNGEDY"
     gene            5111..5332
                     /locus_tag="KRL22_001400"
     CDS             5111..5332
                     /locus_tag="KRL22_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271900.1"
                     /translation="MSKYVLRWQKGLLLDERKINYSCGSIENLKKKAELLAKDDKILL
                     VTIDKVEEVIKDTRSQKMAEYYCDGGIEI"
     gene            5329..6333
                     /locus_tag="KRL22_001401"
     CDS             5329..6333
                     /locus_tag="KRL22_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBH1271901.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDIEAFFQKKISKVSR
                     DNDIRIAVFNDYSNNLIKSCCEQIIYDESSFLNNSKEIASYLFEIMKLNATLESCDLA
                     ICLYSQKDEKKVAILKLDYNKSYTHSIEFKDDKFNIQMSKNEINIQETKTVKIAALVG
                     LSGMNDKYHLRVLDKDAEKEEANSKFVTEFLNATKIKDDKYKTKKFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLREKHEIDINDFVDKTIKDDKLKDSFKEHMEEKGLVEGFSI
                     DKKWVDKKLKKRNIKTDNGFEIKGNLTDFEDPMKYTVRQNQNGSIDIVIKNVTFYEEK
                     "
     gene            6415..6744
                     /locus_tag="KRL22_001402"
     CDS             6415..6744
                     /locus_tag="KRL22_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271902.1"
                     /translation="MKIFLLTILLIIICILANYVKNRIYKKSINNLKYKYSVGEKIIY
                     HQINCYYNRMVGCEILEKCYSTKFRKRNTPLYKVKAYVGDNNTTWVIPEWRIECLATT
                     YGEFPKY"
     gene            6843..7184
                     /locus_tag="KRL22_001403"
     CDS             6843..7184
                     /locus_tag="KRL22_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HBH1271903.1"
                     /translation="MANIYCENYNCKNYFEDMCMLERIEINNFKECESYLEGKNELYK
                     LENGYTIHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEVLEEELTK
                     INSHLELEDLR"
     gene            7310..7717
                     /locus_tag="KRL22_001404"
     CDS             7310..7717
                     /locus_tag="KRL22_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBH1271904.1"
                     /translation="MKVFLVIDGEPVGKERPRFNLATKRTYTPQKTKDYEELIKWLYQ
                     SKVRHYFTGYIKMTLRCYYSIAKSNSKKIKEQKRNNVLRPNKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDII"
     gene            7819..8667
                     /locus_tag="KRL22_001405"
     CDS             7819..8667
                     /locus_tag="KRL22_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBH1271905.1"
                     /translation="MNENINKEITVLGTLEIEGMKFHNIEGGFGEHKKAMLVKDIAEI
                     HNRESRQINELINKNRKRFKDGKDILDLLGVGLDDTKIKELGFTQQSINSYRGLKNKG
                     LLSGIYILSERGYAKLLKILEDDIAWELYEKLVDGYFSMRKELNNPLLSASKELQAIF
                     MLDKKQEVLETKIENVNEKLENFMDDAPLFNIECECIVKEVKRVATKSLGGHGSKAYK
                     NKSLRGKVYSDIYHQIKREFGVDSYKAIKRCQLDKVLEIVNSYKLPIVFEEEIRLLNS
                     QLSIVS"
     gene            8810..9298
                     /locus_tag="KRL22_001406"
     CDS             8810..9298
                     /locus_tag="KRL22_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271906.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAVGYDEKVSPTYAFNSTVENEIIKKERDIARLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKVMDMLYPRIKENELPLF
                     KN"
     gene            9841..10029
                     /locus_tag="KRL22_001407"
     CDS             9841..10029
                     /locus_tag="KRL22_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271907.1"
                     /translation="MEIKKNTQDVVSERKNSLDSEFKIPASGVCYMVEFIQESRKIIK
                     ELDKHFESCLDVLSKARL"
     gene            complement(10009..10326)
                     /locus_tag="KRL22_001408"
     CDS             complement(10009..10326)
                     /locus_tag="KRL22_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271908.1"
                     /translation="MSKNVDIKNLKRFQKKIEKIEQNSKSEFDKIRTIILNKKFMNQH
                     TNFDSFDELLTFGGYIVNSEEDFLAIPDNEFDSFIVENTDFPNWQTMLDTAYSKYLKS
                     CLR"
     gene            10453..11376
                     /locus_tag="KRL22_001409"
     CDS             10453..11376
                     /locus_tag="KRL22_001409"
                     /inference="COORDINATES: protein motif:HMM:NF027488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4868 domain-containing protein"
                     /protein_id="HBH1271909.1"
                     /translation="MNIREIMNILKLERSEVRLYFTMKRGINYISYSPTIEDGLQDYL
                     KNLVCEYLLRFEDIEQVMFSPIGYKDETIETCDIEYIGCYEKVIESYREENLSRDNIE
                     NNIINKLNFYCLNIKFEENNQEKEINFFRRVTKFKKLSSKGFMGFIKNNRFKKLDSNL
                     LGLDGFIDIAIYGQDVLIFNHISLERIFSIADQYLEKAQNTIDIIRDINRIDNFEQFE
                     EDCLNDRRITRTLTKMLSEEARLENCFDNFANVVNAIDLFQLDINIDRNGERDKVIYE
                     NKEQLMDIIRLVRDSYYKSIIHDRKGIDDSI"
     gene            11399..11983
                     /locus_tag="KRL22_001410"
     CDS             11399..11983
                     /locus_tag="KRL22_001410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271910.1"
                     /translation="MNRLNYLNMRIKMFISSYLPLYLILLTIYSDKINSFDKIKLIIR
                     FEDKIVSLFIIAVFILVIISFRTLIDLRRTKGNENHKFEFFNKTEDTIISYMMTYIVP
                     ILSTDFLSTKTMTINLILYSLIGLMYIKLNLIYLNPLWLLFGYSVYKSDNEVVIITNI
                     PYGRLKTLRNTNLKSSYLGNDIYLIQRSENDNIN"
     gene            12051..12743
                     /locus_tag="KRL22_001411"
     CDS             12051..12743
                     /locus_tag="KRL22_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271911.1"
                     /translation="MQDVKEKVKKDYLKGMKQKEISSKYDISLNTLKSWIKRYNWSKE
                     KKKGAPINKRGAPFSNKNSVGHGAPKENKNAEKFGFFSKYLPEETRELIQEISIKDKF
                     DILWEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQAS
                     FLNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKNRVEKLKCEVRELNRTDDEDDEL
                     KIVIDYGDSNDN"
     gene            12721..13974
                     /locus_tag="KRL22_001412"
     CDS             12721..13974
                     /locus_tag="KRL22_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBH1271912.1"
                     /translation="MVILMITRVQFNPSFKEANFTKKRYRAMKGSAGSGKSVNVAQDY
                     ILKLGDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQAGKYWKTTLNPLEIK
                     SKVTGNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGI
                     LTNPNLYYQMTFTFNPVSATHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMKM
                     REEQDPEGYKVYGLGEWGETGGAILKNYVIHEFPTEFEYFDNMRLSQDFGFNHANAIL
                     RIGFKDGELYICNEIYVHEMDTSEIIKIANSRGLEKTLFMYCDSAEPDRIKMWKSAGY
                     KAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEF
                     MDDAMAALRYSIDNKLKNNGISFLK"
     gene            13980..15419
                     /locus_tag="KRL22_001413"
     CDS             13980..15419
                     /locus_tag="KRL22_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH1271913.1"
                     /translation="MLNIYISETDLIKAQLKKESTFNLVKVIEHYILKHRPEKYKQGE
                     EYYYGNTDINNKRRYYLLDGAKVEDFTKVNNKAVNNYHKLLVDQKVDYSVGNPIVFNA
                     DDNDFTKLLNELLGEEFDDTITELYLNASNKGIEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDSKRQRELVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFIERGNSFVQELLYDEYG
                     KMIDIQEGHFRINNKEQGWGKVPFIPFKNNEKCVSDLTFYKSLIDIYDNNISTLADNL
                     DEIQEVIYVLKEYPGTSLQEFIDNIRYYKSIKVDDGGGVDKLEINIPVEAKKELLDRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISGSKSYDYKTVQITFNHSMIINEAEKIDMAAKSTGIISDETIVSNHPWVEDVNDE
                     LDRLKKQEDTQKEYDDLIPNNQDGVIDET"
     gene            15409..16902
                     /locus_tag="KRL22_001414"
     CDS             15409..16902
                     /locus_tag="KRL22_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBH1271914.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSVKYYLELEKQYKLAMNSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKIISKPWATDGLNFSERVWGKHRPALVNELHTKLTQSIIRGENPKNLV
                     NDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLRTSNICRE
                     LDGKVFDMKDYQVGITAPPFHCRCRTTTAPSFEDEEGYRAAKGEDGKTYYVPSSMKYN
                     EWYEKYVKNNSKQTGGKYTKGDIEWNIRREEEAELYYNNIRNRKDDISKIVKNTNWSE
                     KSIGQIKNHIFYNTHIMRDGTRRMLDSDYSMSVAWQRLINGTHEDIDILLLKHEYLES
                     IFEKKYNISNLEAHRMTEKKHDWYKELIKKKGEFEEDDCLNELIRKE"
     gene            16868..17110
                     /locus_tag="KRL22_001415"
     CDS             16868..17110
                     /locus_tag="KRL22_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271915.1"
                     /translation="MIVLMNLLEKNNEYVMYSYGYEENKLDGRIKIYLDDFYNYEIIK
                     ESKDEHISKSATLKAISKLIKAAKNNDLKKEMSYQC"
     gene            17182..17376
                     /locus_tag="KRL22_001416"
     CDS             17182..17376
                     /locus_tag="KRL22_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271916.1"
                     /translation="MCILTQVIVVVCVVQIFINCIANVNVGILCNKLKKENKANIDKV
                     SDEILKKVKEELNKSLDKSL"
     gene            17420..17983
                     /locus_tag="KRL22_001417"
     CDS             17420..17983
                     /locus_tag="KRL22_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBH1271917.1"
                     /translation="MDWLKELLEGIKIEDNKIDIASLQKSIEKKIKETTVTQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVESLKTTYETDKKTLEETYKKEIEEKDFNYWLNDAF
                     KSVKCRDEIALKAHLDMEALRNSKDRQKAFEEQINPLKQDKDYLFNVTLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            17995..18894
                     /locus_tag="KRL22_001418"
     CDS             17995..18894
                     /locus_tag="KRL22_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBH1271918.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATENNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTANVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDGGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLIHPSAIITPVSYQFSTLDEPRAVTEGKYLYFEES
                     FEDVFILNKKADAIQFVVEGAGA"
     gene            18894..19127
                     /locus_tag="KRL22_001419"
     CDS             18894..19127
                     /locus_tag="KRL22_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271919.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKALKYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            19137..19538
                     /locus_tag="KRL22_001420"
     CDS             19137..19538
                     /locus_tag="KRL22_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271920.1"
                     /translation="MENNRIDDIERRLQGFGYVLKDGDKWLIDFVREKIENIIKLDCN
                     IGEIPKELHNIEVDMIVGEFLFTKKNMGQLDIESLNFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLVAYLTTYGKNKILTFRCLRW"
     gene            19532..19894
                     /locus_tag="KRL22_001421"
     CDS             19532..19894
                     /locus_tag="KRL22_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271921.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQTIKLFVSPNISVKAGSKLIITNQNNITKEYIRSGEP
                     AIYPNHQEVLLELCEDKA"
     gene            19894..20319
                     /locus_tag="KRL22_001422"
     CDS             19894..20319
                     /locus_tag="KRL22_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBH1271922.1"
                     /translation="MARWGSVDFREFKRACKRMEKLTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNLTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQGQIDKIIEKKLLILLKGVFDA"
     gene            20312..20749
                     /locus_tag="KRL22_001423"
     CDS             20312..20749
                     /locus_tag="KRL22_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271923.1"
                     /translation="MLNNIIDGISIKLDKTFGESYTIYSEDVEQGINEPCFFIVPLNP
                     SKVSYLSGRTLKKNSFDVHYFPKSNDKSFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNDTDKMDTVELFGGLKRGDNFE"
     gene            20742..20918
                     /locus_tag="KRL22_001424"
     CDS             20742..20918
                     /locus_tag="KRL22_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271924.1"
                     /translation="MSKTLSKEDNYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEEIINNFMKGVS"
     gene            20919..22229
                     /locus_tag="KRL22_001425"
     CDS             20919..22229
                     /locus_tag="KRL22_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBH1271925.1"
                     /translation="MALGGGTFVTQNKVLPGAYINFVSATRATSSLSDRGIVAMPLEL
                     DWGIDEEVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDIQAAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLAITTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDTGLLESSLVYWATGAIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     EKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVS"
     gene            22250..22726
                     /locus_tag="KRL22_001426"
     CDS             22250..22726
                     /locus_tag="KRL22_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH1271926.1"
                     /translation="MAKNITMKSKDAISASLAECYVTIEGKRYLLMQCIKVEAKFKKN
                     KSKIPILGQTGKGNKTTGWEGTGSATVHYNTSIFRKLMLRYKETGEDIYFDMQITNED
                     PTSSVGRQTIILKDCNMDEVTLAKFDADSEYLDEDIDFTFDDWDMPEEFKILLGMI"
     gene            22795..23235
                     /locus_tag="KRL22_001427"
     CDS             22795..23235
                     /locus_tag="KRL22_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH1271927.1"
                     /translation="MSNLSAFLSQNAIKNENVMYVASDRFLDEEGKPVEWELRVLSSE
                     EDEVLRRNCTKRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDVELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN"
     gene            23577..23735
                     /locus_tag="KRL22_001428"
     CDS             23577..23735
                     /locus_tag="KRL22_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271928.1"
                     /translation="MDNFLQGVLASLVASLIVYLTSKLFKKVKSHSNTTKSDFDFKLT
                     IKFKRNKH"
     repeat_region   24015..24636
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=24015..24043
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            24795..24962
                     /locus_tag="KRL22_001429"
     CDS             24795..24962
                     /locus_tag="KRL22_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012159739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271929.1"
                     /translation="MPSKKIGRPTDNPKGSRITIRLDEESKNILEKYCEKEDIDKAEG
                     VRRGIKLLKDK"
     gene            25086..25904
                     /locus_tag="KRL22_001430"
     CDS             25086..25904
                     /locus_tag="KRL22_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
                     /protein_id="HBH1271930.1"
                     /translation="MNNELMNFENNELGIKVRTIKYEDGSIGINAEDAARGFGWITIA
                     TSGNETIRWSRMNEYCKDFGFLNLLGKDDYIPESLFYLLGMKAKNETAVKFQTWLAVD
                     VLPSIRQTGAYITNNANPEKLREKASEIEKLQLAYNSTSMLKELLDDAGFDNKSKLLT
                     AKTLYKKAGIDLPIEIDEEEHYFDTKQIASKLKIYSKSNKPAQLAICEIIKKIDLEEN
                     EVKGVWETNGSWTGTVNKYTESVINKIKCWIDENNKPTKIQGEKKNFHVVYKIE"
     gene            25956..26132
                     /locus_tag="KRL22_001431"
     CDS             25956..26132
                     /locus_tag="KRL22_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271931.1"
                     /translation="MRESLLNEYNLKTDEDVEYFVKFANALYELKQNSEEKFQEYAEI
                     LRGILREQEERKNK"
     gene            26894..27454
                     /locus_tag="KRL22_001432"
     CDS             26894..27454
                     /locus_tag="KRL22_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012424789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1271932.1"
                     /translation="MKKKVCFLFSILIVICLAIVGCSNSESPEESSKNNEPKKEEKKD
                     KEVVIGEKIISDKMEITINNIEFSYDVLPKVKESLYTHYPAESGKVYIDIAADIKNTQ
                     KQELNCSDLLTIEANYNDGYKYSSQTIVEDETTGFTYDNISSIDPLETKGVRFIIDCP
                     DEVKTSDKPVILSFTFDGNKYVYKMK"
     gene            27498..28067
                     /locus_tag="KRL22_001433"
     CDS             27498..28067
                     /locus_tag="KRL22_001433"
                     /inference="COORDINATES: protein motif:HMM:NF024637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HBH1271933.1"
                     /translation="MDDIVEYIFCSECGAKCLKGSKFCSECGTEIADIKMLNESIIKE
                     KEYDLKGIDLQHVMQETSFIKASSVRRLKELTGIELDDCRKILEEPYQKYYNENADML
                     EEKRKKEDDISKIRKAKEEKKEKEKIACCPACGSTSLTTHKKGFGIGKAITGATIAGG
                     IGLVAGNIGAKKVRVTCLNCGKQFWAGKK"
     gene            28188..28970
                     /locus_tag="KRL22_001434"
     CDS             28188..28970
                     /locus_tag="KRL22_001434"
                     /inference="COORDINATES: protein motif:HMM:NF021378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBH1271934.1"
                     /translation="MGLFGGKEPCCICGGKGKNKVLENEYLCNNCFVDFTIFSSGRLK
                     TTSAMQVLADHEGIRKFINFSKKNRELLEKFVETNKINKFISIDENNKFIKISDIRKG
                     GDIIETVYATDEIIEFELLEDEESIVSGGLGRAVVGGALFGATGAVVGGVTGKKTTRK
                     IVNTFKIKITFNNINNPLEYINLINTRTKTNSSIYQNACNEAQEILSVLSIIVKNNDK
                     ANNEQDKTSSSIEQVKGLKELLDIGAITEEEFNTKKKELLNL"
     gene            29035..31386
                     /locus_tag="KRL22_001435"
     CDS             29035..31386
                     /locus_tag="KRL22_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBH1271935.1"
                     /translation="MATIQTSIRIFDGMTPAFRSMTASINTTINSLERLQGRLNNPLN
                     TGGIQTSHQSLNNIENILTRIEQNIGKADEQQRKFNEDINKGASNTDRLLGSVKKVVG
                     TYMGLKTIGGLANLSDQMTSTNARLNMINDGQLSDGGLNKMIFQSAERSRASYLDTAQ
                     IVSRIGMNAGSAFSSTREIVSFAEQLNKKFVIAGASTEEMNSALLQLTQGLGSGVLRG
                     EELNAVFESAPNIIKSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAASAETNAQFE
                     KMPLTIGQIFTSIKNNAVMIFGAIQKKIEDTVSSGGFRTFIVNVTDSLYVLGAVGYSV
                     FNGFIDLLSSPTFQGFANMMIVGISLITQGFGWLLTVLGSVINFISQGWSIIQPILIT
                     SIVLWGLYKTAVIAGALVTAIQVVWIALQTFWTNLLNGSLLTNIMMNIAAKISTDALS
                     GSMLLLITTIVMVVAAVALVIAAIFVAVAIFNHFAGTSISATGVVVGAFYFLGTCIYD
                     VFAGAWNIVMAFAEFFVNSFNIVIYNVQLLFYKFQNFVINAMGDVGGSFDNCATALAN
                     AFVSAANIAIKGINGVIKTLNLIPGVNIKTFGSLDKIDSFVKQYKDYQKTLKEPVKPA
                     EWKAPTMKLKNPVDSFKKGYEVGQNLENKIKDAFDISKIAEKAKKDLGLDDLWDDKYG
                     LGDRFGSAGLNSPLNDAAKNVKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFT
                     GVNIKIDMNNTNNISKDADVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            31398..32087
                     /locus_tag="KRL22_001436"
     CDS             31398..32087
                     /locus_tag="KRL22_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBH1271936.1"
                     /translation="MAYDFYLDGVQLPIAPPKLEVKVTNKNKTVDLINVGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGTFKDVQFFLSKLELLKTDCKPFQFIVSREMGGKVLFN
                     TNMKVSLEEYNIVEDAENASDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPNVKIEPK
                     RVDSVNAPSNKTYTVKSGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKNLSKY
                     TIYKGQVLKLG"
     gene            32080..33972
                     /locus_tag="KRL22_001437"
     CDS             32080..33972
                     /locus_tag="KRL22_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH1271937.1"
                     /translation="MADELVLANDRDVRLVIAHWEDFYEPTVLDGITWEIERRGTPSK
                     LEFTIVMDDILQFCEGNSVRLYFKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELIKMLAKDFNLKYNVIEDTKYKLSRVEENKTLFDMILTALDDTLRE
                     KKEMYTLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSTHMRSWGILQMFETVDKNMNEAEIKQKCDILLKLYNKKTKSLSLKN
                     ALGDIRVRAGCLVPVFLNLGDIKLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSTTKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFLKKHPVFEYGDKVKIILPGTAYDNKVYTVKDNG
                     GRIYVETNGTYHIDILLANASECKKFGRKNGYIIIGGDEEQTYQVEGNNQSSTNNNSK
                     EDKLISIAKSKLGCNYVYGAEGPNNFDCSGFTQWCYKQIGIKIPRTASAQSKAGKAVD
                     LKDRSKWKAGDLLCRIGGGSSNHVVMYIGNNQIIHSPQTGDVVKIESVNSYRKGKAYT
                     HVRRFI"
     gene            33986..34246
                     /locus_tag="KRL22_001438"
     CDS             33986..34246
                     /locus_tag="KRL22_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBH1271938.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESISPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            34251..34670
                     /locus_tag="KRL22_001439"
     CDS             34251..34670
                     /locus_tag="KRL22_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH1271939.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLHIEKSKIDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISFVIPELGRRIKEALIQDDR
                     IENVDNFEFQNIKGKLQCRFSVHTKYGNIKAEKVVSV"
     gene            34671..35720
                     /locus_tag="KRL22_001440"
     CDS             34671..35720
                     /locus_tag="KRL22_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH1271940.1"
                     /translation="MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLPATNTIAKGVFNIDIPIDSRFNLGE
                     YNYVAIERISEGIYKMKCETAGPIFELGQLIPIEYINGLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNIQNYKDEVNKIQDVGGVKVYPVWNGGGTVKLVIINSNFKV
                     PSTDLVNLVQEEIDPLQNQGEGLGLAPIGHRVTVEGVTSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDITNTMINEVKSNL
                     TIDSNSIVVRGEVVG"
     gene            35713..36330
                     /locus_tag="KRL22_001441"
     CDS             35713..36330
                     /locus_tag="KRL22_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBH1271941.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVGNKEIKILHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEVTIF"
     gene            36342..37145
                     /locus_tag="KRL22_001442"
     CDS             36342..37145
                     /locus_tag="KRL22_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH1271942.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     IGTVNTKIDTTKTELTSNIETAKTEIDEKIGDTTQLTTTDKTNIVGALNEVKTSVDSI
                     ETTAEKTSYNNATSNLAATNVQGAIDEVVRKIEKFNEVNISIQNDMLPI"
     gene            37163..38803
                     /locus_tag="KRL22_001443"
     CDS             37163..38803
                     /locus_tag="KRL22_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271943.1"
                     /translation="MQTEWDFNYANYVQNVSLLPGRYKLECWGACGGTLGASDWTECA
                     KGGYSKGEVILKKRTNLCICVGQSGYEKLDTGSTLTRTGFNGGGRTNAHSINGNYYSK
                     YGGGATDIRAYYTRATWDSAEGLLSRILVAGGGGGMKNNFASARSIGHGGGYVGENGI
                     GRDRDFCGGGSQYQGGTSYDTEEYHGSLGKGGYGGIGVGGGGGWHGGAGSYSNECGGG
                     GSGYALTKDSYKPPGYIPTSEYWLENVVMTTGGNTTRADGYAKITLLQALPFLNISSY
                     NSTTATFKADHTDPTLLTKIEYFIDDTLKETITTDLTLEKTINYTLEDNALHTLKIVV
                     TDSANATAEKNVSISKGIAPLPAGSTTDEVTSKWMEIKDTFKSGKTSIINTLALKNID
                     ASLNNTLVELSEKIKTSFDSSDASVEDLTNKLTQANNTISQLNTKYKFAYSLDLTVHW
                     FIDCGFKPDFVIYECINNHGKFLVFLTPFNYSVFDIGNLGWTITAREDISKKDSFSIN
                     NINQFWGTKIRDTGFNNADMPKDSLNDRYVFWIAIKCL"
     gene            38816..39115
                     /locus_tag="KRL22_001444"
     CDS             38816..39115
                     /locus_tag="KRL22_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271944.1"
                     /translation="MKNIGRIVFYDNDTGDILMFYGEKTVSDSIDINIPKIDSIELPY
                     GSIDYTRNRLIGINVETKEPILEEIPVYVSEEEKRIQELENQILIAENEKVGGLL"
     gene            39115..39297
                     /locus_tag="KRL22_001445"
     CDS             39115..39297
                     /locus_tag="KRL22_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271945.1"
                     /translation="MNINNVVVRILAERILNKGLNPLKNREFQLDDVTNAEYRKAVED
                     YIIEHSGVVEGAEPTK"
     gene            39333..39563
                     /locus_tag="KRL22_001446"
     CDS             39333..39563
                     /locus_tag="KRL22_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBH1271946.1"
                     /translation="MNEELFEADLKRHETRINKHGEEIDELKIANIESKAELKALCEN
                     LNSLTSMLKWLIGTMITTLIGFFIFAIQRGIF"
     gene            39583..39840
                     /locus_tag="KRL22_001447"
     CDS             39583..39840
                     /locus_tag="KRL22_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBH1271947.1"
                     /translation="MDNLISFIPEQLLILVAALYVIGAGCKKYKQLDNKYIPVVLLAL
                     GIGFSIWMLGLNADSVLQGVICWGISIGINQTYKQLKEENK"
     gene            39840..40655
                     /locus_tag="KRL22_001448"
     CDS             39840..40655
                     /locus_tag="KRL22_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1271948.1"
                     /translation="MKIGVNCGHTKTGAGSGAIGKINESIETRNVGYKVIDKLKTLGN
                     NVVDCTIDKASTQSECLSKIATQANRQDLDWFISIHFNAGKGRGCEVYTYKGKQYQDA
                     IDVCKKISDLGFTNRGVKDGSGLYVVKKTKAKSMLIEVCFVDSEDANKYLSLGADKLA
                     TAIVEAITKHISSAEENNYNRYKHTIVYSGDDKVSADILGLYYKREKESYLVTDIKDY
                     KPHRTQNLYVIGGVTCNKMKEMSKTTGEKFTQLYGNDVWSTMDKAIEFVKEKL"
     gene            40672..40968
                     /locus_tag="KRL22_001449"
     CDS             40672..40968
                     /locus_tag="KRL22_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271949.1"
                     /translation="MLIQEKSFYPNDIYPKIDFLKIKRQLKSIYKNDLSDCGSICIIE
                     RKDYSLSVNSIGEVNIYYDLKFKQCVQDAVKDIELMFKSQIRSFYLIDRLEGSN"
     gene            41514..42077
                     /locus_tag="KRL22_001450"
     CDS             41514..42077
                     /locus_tag="KRL22_001450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271950.1"
                     /translation="MNNYSIMFENKSILDLKQTCYLDSLYNLFEEKIQYVTKTLKNNN
                     IEEDEWDIQFIKEDALQSIKNIEEDFITDKTLDWRINLSKIIKKVLDKSKANFKIADE
                     MYHNPMKKSEQYYDLLSNIFDNLEELICIKYKEYEISRNIRFTNIGNLVNNDNSSNYI
                     DNEHIEFDFNFKFEIEDYDNDDYALAA"
     gene            42095..42526
                     /locus_tag="KRL22_001451"
     CDS             42095..42526
                     /locus_tag="KRL22_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HBH1271951.1"
                     /translation="MELDKMKYRKLVNDVELVNVLIKNIELSDVILHKDENIKNESIK
                     CDVNMKYECEEFKKLSEVVEFYPKFNLRIECQGEGLVNLKFELRAIYKFNSIEDYEDD
                     YILMFIERNVPVNIWPYAREIISSITTRIGYPALVISPYKA"
     gene            42528..43232
                     /locus_tag="KRL22_001452"
     CDS             42528..43232
                     /locus_tag="KRL22_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271952.1"
                     /translation="MRLKFKSKESTSREKHQSAESLAKFMLNNKSFLGITLSILDEWK
                     NNIDSSKIEDIVKNNFRFEESIIKDKNYKEFIKLLNSFYNGTEDELNGRRGRFLELIW
                     DVVGTYNGKEFTQKIDEAIVLENEVKISEKDIDIVYIGEIKDKGIANFIEMHECKASA
                     NTTLRTPLKPKHRGKLELMQSVIEISETEEIKCDGLIITFNANKRRLERKLKSYGFEY
                     FKIIPRAEIEERVFNK"
     gene            complement(43482..43670)
                     /locus_tag="KRL22_001453"
     CDS             complement(43482..43670)
                     /locus_tag="KRL22_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271953.1"
                     /translation="MTKTILCDYCNKGINKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHDYSKK"
     gene            43931..44074
                     /locus_tag="KRL22_001454"
     CDS             43931..44074
                     /locus_tag="KRL22_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271954.1"
                     /translation="MSEFLLGVLASLTASFITYIISRKVKSHSGRSDFELDVKIKFNK
                     KRH"
     regulatory      complement(44277..44372)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            44648..45529
                     /locus_tag="KRL22_001455"
                     /pseudo
     CDS             44648..45529
                     /locus_tag="KRL22_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            45534..47252
                     /locus_tag="KRL22_001456"
     CDS             45534..47252
                     /locus_tag="KRL22_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH1271955.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWSYDL
                     RLTLEHFSMKNSIDGIKPFINSIKISLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(47332..>47483)
                     /locus_tag="KRL22_001457"
     CDS             complement(47332..>47483)
                     /locus_tag="KRL22_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1271956.1"
                     /translation="ENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKI
                     NKQYQ"
BASE COUNT        19420 a         4893 c         8823 g        14347 t
ORIGIN      
        1 gctaaatcat aacagcactt tgaaaactaa atacggaata ttttgaaaat agaggggtga
       61 tttaaatggg taaaaaaagt gaatacacag taacaacagt tggtgaacca aatttagatg
      121 cattaggcga aactttagct aaaattctta cagagaaatt tggggtacta ataactcata
      181 catacattga gaactattat gttgataaag agagaggggg tgatgtagat ggagctattg
      241 aaagtgaact ttaatctaga gaaattaaaa aataggaaat gtagtgagtg taagttctaa
      301 gaggtttggg ttcaatatta attgtattgt agtagtagca actgaggagg aactaaattt
      361 agcttattat agcaaagata agggatgtat tgagtatcaa gcattgatac cagaggatat
      421 tagatatggt gattatattc ttgaaagatt aggttaggag gaaataaaat ggcagcttta
      481 ataatagtag gtttatttgc aatatgttta gtaggattag ttcaaaatag agattaatta
      541 aaaagggggt ttaattatgg aaagtttaaa aatagtaaaa caatatgttg aaggacagtt
      601 aaatttatct agtttagaaa tagacaaaaa taaggagact tatgagattc tcaaaaataa
      661 atctagcaga gatatgttag atgacattaa tttaaatgat gcattaagag aagtaacagt
      721 aaacgaaaga ttaaaaatat ttgctgagtc attactagag ttgttagata cacaaatcaa
      781 aataaaagag agtgaagaaa gtgaggacta taaaagactt tgtatgtact tagacgaatt
      841 tggaagagat agacctatag atgtccagat ataaaaaaag agccattagg agtggctcga
      901 ttcagaaaat atttaaaaat aaaaatatga ctatattata gcataaacgg agggaaatta
      961 tgagtacttt atatgaatta actacagatt tattagaaat agaagaaggt ttaacagaaa
     1021 taacaggaaa tgaagctgaa aaactagagg aaataaaaga aataataaaa caagagatac
     1081 aaaataaaaa cactaggata gtttcagtga taatagatat tgatagtgat ataaactctt
     1141 tagacttaga gattaagaga atgcaagagt taaagaagat taagaagaat agtcttgata
     1201 gattaaaaag taacataaag gaatgtatgg aactgcttgg tattaaaaag gtagaaacat
     1261 ttttaggaaa tataagtata agaaagtcag caggtagctt agtcatagaa gatgaagaaa
     1321 agatacctgc tatatataaa acagtagagc aagttgtaaa agtagataaa aataccatta
     1381 aagactttat caaaaaaggt catgaggttg aaggttgtag gattgaatat ggaactacac
     1441 taacaattcc aaaagctaaa aaagagtagg tgaggaccat ggaaactaat aatgtttata
     1501 taaaacttgt aaatatacag agtactttaa aagctcctaa aagtcaattt aatagctttg
     1561 gtaaatacaa ctataggagt tgtgaggata tactagaagg tttaaagcct attctaaaag
     1621 aagaaaaagc attggttgta ttggatgata atattgttca gataggaaat agattttatg
     1681 tagaagctac agcaacttta atagatgcag aaacaggaga gaaagtatct acaaaggcat
     1741 tagctagaga agatgaaact aaaaaaggta tggatttagc acaagtaact ggaagtgtat
     1801 caagttatgc aagaaagtac gctttaaatg gattattttg tattgatgat acaaaagata
     1861 gtgatgcaac aaataaacat ggaaatgagc agaaaaaaaa agaagttaat gagagcgaat
     1921 taaatatact atattcgcta ggagaatcta tagaaaaaga taaaaataga gttgatagtg
     1981 aagtatataa gaagtttgga aagttagcag tagatttgac taagcaggag tatgagaaag
     2041 ttttaaatgg atataagagc attttagaga agcaaaaaca agagtaggtg atagtattgg
     2101 ggattataag agtaagcaaa gacaaagata atccatatgt agttttaaat aaaacttgtt
     2161 tggaagatgt aaaattaagc tggcaagcaa aaggcttaca ttcatatctg attagtaagc
     2221 ccgaccattg gaaaatctat gttaatgatt tatataaaag aagtaaaaat gggagggatg
     2281 ctacagcaaa tattttaagg gagctcatag aaaatggata tataacaaga acaccttgtc
     2341 gagattctaa tactaataag atgcttggag gatatgatta tcaagtatat gagataccac
     2401 ttgaaaatcc tcagaagcta aaatcccgaa aaactgattt cccggaaacc ggatttcccg
     2461 gaaaccgggt ttctcggaaa ccggaaaaca cggaagtagt aagtaatgac tttaaagtaa
     2521 ataatgatat tactactatt gttattaatg aacaacctca acaagatgaa accacctata
     2581 taaaaaaata ctttgaaaaa tatataggtg tgattactcc taataacttt atagagttaa
     2641 tgagttactt agatgatgga atggaagctg atgtaattat aagagctatt gatgaagcaa
     2701 tatcaaatgg agttaagaat tataagtatg taaagacaat attaaacaat tggatagaag
     2761 caggtgtaaa aactaattta gaacttacag agtatcaaaa tgagtttgag aggaagaaaa
     2821 agagtaaaca ggagaagaaa cagtctaatc ataaaaatgt gaatactcct aatgtgagta
     2881 aaaataagtt tcataacttc aatgaaacct ttactcaata ttcacctgac gaactagatg
     2941 acataattaa gaaaagtcaa aaggttaaat ttaaataaaa ttatacttct aggaagtaaa
     3001 tatcaatata ttacttccta gaaaggggag gtataaaatg gctaaaattt ggatggatgc
     3061 aaatgaagtt ctaagtaaaa ctatggattt agaagatatg tttgaactta atttaagagc
     3121 aataagaaag agaaatgaaa aaataaaaaa tgaaattgag aaacaaataa aatatgaaga
     3181 ttcagaaata aaaactacaa atcgtggtgg accaggaaaa attataaaaa ttttcaatat
     3241 aaatactgga gaggtaaaga ttcttaagag tgctgaagaa gcaagtagat atataaaggt
     3301 tagtcgtagc tatgcaagtt atttagctag agaaaataaa tcaactgagg atggttggaa
     3361 agcagagtat attcaagagg tgtcagatgg tattagcaaa tgtggaacaa gtaattaagt
     3421 tagctgaaaa gatattaaat aagaaaaagt gttctgtcaa taaagctatt gatatagcta
     3481 taaaaatatt gagtaaatat gagtatgagg ggatgttaga aaaatgaaat taaaagatat
     3541 tataaaactt ggagaaaagt attgttattg ccccaactgt ggtaatgaca agataggaaa
     3601 caatgaaggt aaattaatag ttgaagaaca cacatactat agggaatgtt catgtggatt
     3661 caatgtatta attgatgata gaaaggatga gatataatgc atatttcaac gattattttg
     3721 ctgttaatag gaagttttat agctggtaga gtttatgagt atagattgaa tctgaaagag
     3781 tgtgaaaatt gtgataacaa aagaggtgta taagaatgga tgatagattg gagatttgca
     3841 aaaaaatgtt tcctatcatt actaaaaata ctagattact ttgtcattat tgtgatggta
     3901 gaaatatttg cagttatgat gaagaaaaag ctcaagaatt attgagaaat gaagaaggta
     3961 ctaaaaataa ctaactttga aatgataaaa tatctaatta aaacagttta gaggaggaat
     4021 agattatgga atataaagaa tatgaagatt taaaaaatag agtagaaagt tatgaggatt
     4081 tacaaggtag tgcagagttt gcagggagag ttatagaaaa tcttgaagat gtagattgtc
     4141 ctataagaat aggatttaaa tttcctagca aagaggatta caaaaatata gaacttgata
     4201 tagctgctaa agattcaaat tcaattttta taagaacaga gttagcaaaa gcatttaaag
     4261 agattttatc taaatatgaa atggatatgg aaaatatgta attaaaacag tttagagagt
     4321 tgcaaaatat cttttagtat gaatattttt gaagtgtttt gtaactctca aaaatgaaaa
     4381 taaggggtgg gataataaaa tggatttaaa taaaattatg aatgatgcac tagtggaaat
     4441 agaagaaagt ggctttgtag aggaaacagt taaaaaagaa ttagaagaaa caataaaaag
     4501 agctgtgaat gaaatctttg gaagctatag taaattcaga aaaaatattg aacaacattt
     4561 aggtgaaaat ataaatataa atttagatga attagatata caaaaataca atttacttgt
     4621 ggcaaatgtt gtaaaagaaa aggtagatgc tacgatgaag gggcaaggta ttgagcattt
     4681 aaaaagaaac ttggataaca tgcttgtagg tcttaagaaa gaatacaaaa tgagtgaatt
     4741 attagaagaa ttgaaagaag ataaatacaa ccttgacgag tacccatgtg atgaagactg
     4801 tataacattt atccttgaat ctaattttaa ttcagaatgg gcaagatgga tagactttga
     4861 tgagtgtcct aatgtaagca gaaataattg tgaacattct atactattaa gaaacgatgg
     4921 aactattgca gcatttagat accaaaacag agaaatatca tcaaaagata taatgaacgg
     4981 atttggtaat tttggggatt tattatttaa gatatatgca cataattcaa aaattatctt
     5041 agatttaggg aatgatgtag acgattatga cttaacaaat ggagaagatt attagaatag
     5101 gggtgaataa atgtcaaagt atgtattgag atggcaaaaa ggattattac tagatgaacg
     5161 caagataaat tattcttgtg gaagtataga aaatttaaaa aagaaagctg aattattagc
     5221 taaagatgac aagatattgc ttgtaacaat agataaagtt gaagaagtta taaaagatac
     5281 tagaagtcaa aaaatggctg aatattattg tgatggagga attgaaatat gataatacac
     5341 aaatttataa tacatgtttt agataagaat agcgatacac caatactaaa tgattttgag
     5401 ggtagagtca gtcaagatat tgaagctttc tttcagaaaa aaataagcaa agtatcaaga
     5461 gataatgaca ttagaatagc tgtatttaat gactatagta acaatctaat taagagttgt
     5521 tgcgaacaga ttatatatga tgaaagttca tttttaaata actctaaaga aatagcatct
     5581 tatctgtttg agattatgaa gttgaatgct acattagaat cttgcgactt agcaatttgc
     5641 ttatactctc aaaaagatga aaagaaagtt gctatattaa agcttgatta caacaagtca
     5701 tatactcatt caatcgagtt taaagatgat aaatttaata tacagatgtc taaaaatgaa
     5761 attaatatac aagagactaa gacggttaaa attgctgctt tggttggatt gagtggaatg
     5821 aatgacaaat atcatcttag ggttttagac aaggatgcag agaaggaaga agctaattct
     5881 aagtttgtta cagagttctt aaatgccact aagataaaag atgataagta taagactaag
     5941 aagttcaaaa atacagctga gaattggata actaatgctc ttagtaatga tataaaacaa
     6001 gcagaggatg taagaagtat attaaattat actttgagag aaaagcatga aattgatata
     6061 aatgattttg ttgataaaac aattaaagat gataagttaa aagatagttt taaagaacat
     6121 atggaagaaa aaggtcttgt tgaaggattt agtatagata aaaaatgggt tgataaaaag
     6181 cttaaaaaga gaaatataaa aactgacaat ggctttgaaa taaaaggtaa cttaactgat
     6241 tttgaggacc caatgaaata tacagtaaga caaaatcaaa atgggtctat agatatagtt
     6301 attaagaatg taacatttta tgaggaaaag taggtactca tgtgactatt ggctagagaa
     6361 ggagaagtaa ataataagag gatgtaaatt taaactagtt aggaggaata acttatgaag
     6421 atttttttat tgactatact gctaataatt atttgtatat tagcaaatta tgtgaaaaat
     6481 cgcatatata aaaaatctat aaataattta aaatataaat attctgtagg ggaaaagatt
     6541 atatatcatc aaataaactg ttactataac agaatggttg gttgtgaaat tttagaaaaa
     6601 tgttatagta cgaaatttag aaaaagaaat accccgcttt ataaagtaaa agcatatgta
     6661 ggtgataaca atacaacgtg ggttatacca gagtggagaa ttgaatgtct tgctacgact
     6721 tatggagaat ttcctaaata ttaaataata aaaattggtt ggagtataaa tagtcaaggt
     6781 aagtttatga atgaaactag aatgttatag acttactttg acttataaaa ggagtgtgtt
     6841 aaatggctaa tatatattgt gaaaattata attgtaaaaa ctactttgaa gatatgtgta
     6901 tgcttgaaag aattgaaatt aataacttca aagaatgcga aagctatctt gaaggtaaaa
     6961 atgagctata taaattagaa aacggatata ctatacatcc taaagatttg aaaatggtga
     7021 aaagtaaaga ttattctgtt gaagttactc atattccaac tggtattaca gtaaaatgcc
     7081 gttctacaaa tagtatttta aaaaataaaa ataagtgttt ggaagttcta gaagaagaac
     7141 taacaaaaat aaactctcac ttagagctag aagatttacg ctaaatagga agtgagctta
     7201 tgaaacgaag aagatgcagt tggtgtggta agttatttta tcttgaagaa aaatctaagg
     7261 atgtttattg ttgtaaagaa tgtaggaaga aggctaagaa ggtgaaaaaa tgaaagtttt
     7321 tcttgtaata gatggagaac cagttggtaa agaaagacct agatttaact tggctactaa
     7381 aaggacctat acaccacaga aaactaagga ctatgaagaa ttaataaaat ggttatatca
     7441 atctaaagtt agacattatt ttactggata cataaaaatg actttaagat gttattactc
     7501 tatagcaaaa agtaacagta aaaagattaa agagcagaaa agaaataatg tgttaagacc
     7561 caataaaaaa ccagatattg ataatgtggt caagattata gctgattcac tcaatgagat
     7621 agcttataaa gatgatacgc agattgttga ggttgtagct agtaaatatt acagtgataa
     7681 accaagagtt gaggttatat tagaagatat tatttaacca acggaaaaat ccgttcgtta
     7741 gattaggtac tcagtttttc ataaaaatgt gaaaaagctg aatagagaat atatcaaatg
     7801 gtaaaggaga gataaattat gaatgaaaat ataaataaag aaataacagt acttggaact
     7861 ttagaaatcg agggaatgaa atttcataac attgagggtg gatttggaga acataagaaa
     7921 gcaatgctag taaaagatat agctgagata cataatagag aatctagaca gattaatgag
     7981 cttataaata agaatagaaa aagatttaaa gatggaaaag atatattaga tttgttaggt
     8041 gtcggtttgg acgataccaa aataaaagaa ttaggattta ctcaacaatc aattaattct
     8101 tatagagggt taaaaaacaa agggttatta tctgggattt atatattatc tgaaagaggt
     8161 tatgcaaaat tattaaaaat attagaagat gatatagctt gggaattata tgagaagtta
     8221 gttgatggat atttctctat gagaaaagaa ctaaataatc ctcttttaag tgcatcaaag
     8281 gagttacaag ctatatttat gctagataag aaacaagaag tcttagaaac taaaatagag
     8341 aatgttaatg agaagttaga gaactttatg gatgatgcac cattattcaa tatcgagtgt
     8401 gagtgtattg ttaaagaggt taagagagta gcaacaaaat cacttggtgg acatggaagt
     8461 aaggcttata aaaataaatc tttaagaggt aaagtttata gtgatatata ccatcagatt
     8521 aaacgagaat ttggagtaga tagttataag gctataaagc gttgtcaatt agataaagta
     8581 ttagagattg taaatagtta taagttacct atagtgtttg aagaagaaat aagacttttg
     8641 aatagtcaat tatcaattgt gagttaagac aggaatagat ttttctcctt taaaggggaa
     8701 aacctgcaat agttaattaa aagagaaaag gagtgctttc acactccact tgtcaaaaat
     8761 ataaagcttt tatccaagat tattataaca taaacaggag tgtgaaagta tggataataa
     8821 tattaataaa aaagaactat ttaaaaaagt agaaggtaga ctacatcatt ataaattttt
     8881 aagtgcagaa attaaaaatc ttgaattaga tatagaaagt agagaaaatg agatatttgg
     8941 gtgtaaagct gttggatatg atgaaaaagt aagtccaaca tatgctttta attcaactgt
     9001 tgagaatgag attataaaaa aagaaagaga tattgctaga ttaaaaaaac tgaaaaaaga
     9061 taaagaaata gaaaagaaga aaatagaaaa tgcacttaca tgcttagata taagagaaga
     9121 acattttttt aaactatttt ataatagcag aatgaaaaat agtatggttt atatatcctt
     9181 agagatgaac tcagatagaa aaacatgtag atgtgtgagg gaaagattag tgtataaagt
     9241 tatggatatg ctttatccaa gaattaagga aaatgaactc ccattattta aaaattagaa
     9301 aattccccag tttttcccca gaaattccca ctttattccc tactttctcc ccgttttgat
     9361 taaaaaagca tgagataata gtattgtgga aataaagatt tccctctcaa aacttaatat
     9421 ttgactaggg ttaagggatt gccctagtca ctatgaacag actaggcagg gcatgaggat
     9481 gctgttagtt caattctaac tatgttcaat ctttagtttt tctatttcaa ttaatctacg
     9541 gatacactaa aaaatagtat atgaattgag attaaaatct catacaattt tgtatcttaa
     9601 ttcaaagtct aaaaaccgag tggggcttgg taacctcact caccatgcaa gtactggttt
     9661 aatctaggtt cgattcctgg aacttgctcc ctttaataat atgtatcccc cattaaaaag
     9721 gcttagatta atttctaggt ctttttttat acaattttaa tccctcatat tgagggggcg
     9781 aaaataaggg tattcaaatt gaacaccttt tatacaataa attaaaagga gaatgatatt
     9841 atggagatta agaaaaacac acaagatgta gtatcagaaa gaaaaaattc cctagattct
     9901 gaattcaaga tacctgcaag tggtgtatgt tatatggttg agtttataca agaatctagg
     9961 aaaattataa aagaattaga taaacatttt gaaagttgtt tagatgtttt atctaaggca
    10021 agactttaga tattttgaat atgctgtgtc aagcatagtt tgccaatttg gaaaatcagt
    10081 attttcaact ataaaagaat caaattcatt atcaggaata gctaaaaagt cttcttctga
    10141 attgactatg taacctccaa atgtaagtag ttcatcaaaa gaatcaaaat tagtgtgttg
    10201 gttcataaat ttcttgttga gaattattgt gcgaatttta tcaaattcag attttgaatt
    10261 ttgttctatt ttctcaattt tcttttgaaa tcgttttaaa tttttgatgt caacattttt
    10321 actcataata acacctcctt tcagtaaaat tttagcataa taacacagct tattcttcga
    10381 ttgtcgaacg attgctggag gatattatgt tttagtgtag aaatttatat tttgaaagga
    10441 gagggagcat ttatgaatat aagggaaata atgaatattt taaaactgga aaggtctgaa
    10501 gttagattat atttcactat gaagaggggg ataaattaca taagttattc tccaacaatt
    10561 gaagatggat tacaagatta cttgaaaaac ttagtgtgcg aatatttatt gagatttgag
    10621 gatattgagc aggttatgtt tagtccaatt ggatataaag atgaaactat tgaaacttgt
    10681 gacatagaat atataggatg ttatgaaaaa gttatagaaa gttatagaga agaaaattta
    10741 tctagagata atattgaaaa taacataata aataaattga atttttactg tttgaatata
    10801 aaatttgaag aaaataatca agaaaaagaa ataaattttt ttagaagagt aacgaaattt
    10861 aaaaaattat caagtaaagg ttttatgggt tttataaaaa ataataggtt taaaaaatta
    10921 gattctaatt tattaggatt agatggtttt atagatatag ctatatatgg tcaggatgtt
    10981 ttaattttta atcatatttc attagagagg attttctcta tagcagatca atatttagaa
    11041 aaggctcaaa atactataga tataataaga gacattaaca ggatagataa ctttgaacaa
    11101 tttgaagaag attgtttaaa tgatagaaga attacaagaa ctttgactaa aatgttaagt
    11161 gaagaggcac gactagaaaa ttgctttgat aattttgcta atgtcgttaa tgcaattgac
    11221 ttattccaat tagatataaa tatagataga aatggagaaa gagataaagt gatttatgaa
    11281 aataaagaac aattaatgga cataataaga ttagtaagag attcttatta taagagtata
    11341 atccatgata gaaaaggaat tgatgatagt atataattaa ataaaaggag gtggttgcat
    11401 gaataggttg aactatttaa acatgagaat taaaatgttt atatcatcat acttgccttt
    11461 atacttaata ttacttacta tatattctga taaaattaat agttttgata agattaagtt
    11521 aataataaga tttgaagata aaatagtttc tttatttata atagcggtat ttatccttgt
    11581 aatcatctcg tttagaactt taattgattt aagaaggaca aaaggaaatg aaaatcataa
    11641 atttgagttt tttaataaga cagaggatac aataattagc tatatgatga cttatattgt
    11701 tccaatttta tctacagatt ttcttagtac aaaaacaatg acaataaatt taattttata
    11761 ttctttaatc ggtttaatgt atattaaatt gaatcttata tatttaaatc ctttgtggtt
    11821 attgtttgga tattcagttt acaaatctga taatgaagtt gtcatcataa ccaatatacc
    11881 ttatggtaga ttaaagactc taaggaatac aaatctaaaa tcatcatatt taggtaatga
    11941 tatttatttg atacaaagaa gtgaaaatga caatataaac taacaaaaac aggactctaa
    12001 ccagagttct tttttttact cccaaaacaa acaaataaag aggtggtgat gtgcaagatg
    12061 tcaaagaaaa ggtaaaaaag gattacctaa aaggtatgaa acaaaaggaa atatcatcaa
    12121 agtatgacat tagcttaaac actttaaagt catggataaa aagatacaac tggtcaaagg
    12181 aaaagaaaaa gggtgcaccc ataaataaaa gaggtgcacc cttttctaat aaaaattcag
    12241 ttggccatgg tgctccaaaa gagaataaga acgctgaaaa gtttggtttc ttctcaaaat
    12301 atctacctga agaaactagg gaattaatac aagaaatatc tataaaagat aaatttgata
    12361 ttctttggga acagataaca attcaatatg cagcaataat aagagcacaa aagataatgt
    12421 atgttaaaga caaggaagaa atgattaagg agttaaagaa acatgaaagc acagaaaatg
    12481 gtgagaagat agagtatgaa tttcaatttg catgggatag gcaagcatct tttcttaatg
    12541 cacagagtag ggctatgagt gaacttagaa gtttaattaa acaatatgat gagatgattc
    12601 ataaggattg gaatttggct acagaggagc agaaaaatag agttgaaaag ttaaaatgtg
    12661 aagtaagaga acttaataga actgatgatg aagatgacga attaaaaata gtaatagatt
    12721 atggtgattc taatgataac tagagtacaa tttaatccat cttttaaaga agctaatttt
    12781 actaaaaaaa gatatagagc aatgaaaggt tcagcaggta gtggaaaatc tgttaatgta
    12841 gcacaggact atatactaaa gttaggagat aaaaagtatc aaggagctaa cttattagta
    12901 gttagaaaat cagaagccac acacaaatat tcaacatatg cagaacttac aggagctata
    12961 aatcgtatct atggtaagca agctggtaag tattggaaaa ctactttaaa tcctttagaa
    13021 attaagagta aagttactgg taactctata atatttagag gtgttaatga tgcaaaacaa
    13081 agagaaaaat tgaaatcaat taacttctca aaaggaaaat taacatgggt atggtgtgaa
    13141 gaagctacag aacttatgga aagtgacata gacatactag acgaccgttt aagaggtatt
    13201 ttaactaatc ctaacttata ctatcaaatg acatttacat ttaacccagt atcagctact
    13261 cattggataa aaagaaagta ttttgactat aaaaatgatg atatatttac tcatcatagt
    13321 acttatctac aaaatagatt tattgatgaa gcgtattata gaagaatgaa aatgagagag
    13381 gaacaagacc cagaagggta taaagtctat ggacttggag aatggggaga aactggtgga
    13441 gcaatactta aaaactatgt tatacatgaa tttcctacag aatttgaata ctttgataat
    13501 atgaggttat cacaagactt tggttttaat catgcaaatg caatacttag aattggcttt
    13561 aaagatggag agttatatat atgtaacgaa atatatgtac atgaaatgga tacctcagaa
    13621 atcataaaga ttgcaaatag tagaggttta gaaaagactc tatttatgta ctgtgatagt
    13681 gctgaaccag atagaattaa gatgtggaaa agtgcaggat ataaagctaa aggggttaaa
    13741 aaaggaccag gaagtgttaa agctcaaata gattatttaa aacagttaag aatacatgta
    13801 catcctagtt gcactaatac cataaaagaa atacaacaat ggaaatggaa acaagacgaa
    13861 agaactggat tatatcttga tgaaccagtt gagtttatgg atgatgcaat ggctgctctt
    13921 agatattcta tagataataa gcttaaaaat aatggaataa gcttcttaaa gtaaaggagg
    13981 tgttaaatat ttatataagc gaaacagatt taataaaagc tcagttaaaa aaagagagta
    14041 cctttaacct agtaaaagtc atagaacact acatcttaaa gcatagacca gagaaataca
    14101 aacaaggaga agaatattat tatggtaata ctgatataaa caataagaga agatattatc
    14161 tcttagatgg agctaaggtt gaagatttta ctaaggttaa taataaagca gttaataatt
    14221 atcataagct tttagttgac caaaaggtgg actatagcgt tggaaatcca atcgtattta
    14281 atgcagatga taatgacttt actaagcttt taaatgaatt attaggagaa gaatttgacg
    14341 atacaataac agaactctat ctcaatgcta gtaataaagg gattgaatgg ttacatccat
    14401 atattaatag aaaaggtgag tttaaatatg taataatacc agctgaagaa gcaattccta
    14461 tttgggacag taaaagacag agggaattag ttgcatttat taggttttat tatattgagg
    14521 atatagatgg aaacaagata aaaagagttg aatattatac agaaaatgat gtaacttact
    14581 ttattgaaag aggtaatagt tttgttcaag aacttttata tgatgaatat ggaaaaatga
    14641 ttgatataca agaaggtcat tttagaataa ataacaaaga acagggctgg ggtaaagtgc
    14701 catttatacc ttttaaaaat aatgaaaaat gtgtctcaga tttaactttc tataaatcat
    14761 taatagatat atatgacaat aatatttcta cactagcaga taacttagat gaaatacaag
    14821 aggttattta tgtattaaaa gaatatccag gaacaagtct acaagagttt atagataata
    14881 taagatacta taaatcaatt aaagtagatg atggaggtgg agttgataaa ctagagataa
    14941 atataccagt tgaagctaaa aaggagcttc ttgatagatt agaaaagaat ataattatct
    15001 ttggtcaagg agttaatcca gaatctcaaa acacaggtga caaatcaggt gtagcactta
    15061 aatttttata ttcactactt gatttaaaat gttctaagac tgaaaagaag tttaaaaaag
    15121 caattagaga gcttttatgg tttgtgtgtg agtatttaaa gataagtggt agtaagagct
    15181 atgattataa aacagttcaa attactttta atcactctat gataataaat gaagctgaaa
    15241 agatagatat ggcagctaaa tcaactggaa ttatatcaga tgaaactatt gtttctaacc
    15301 atccttgggt cgaggatgtt aatgacgaac ttgatagact taaaaaacag gaagatactc
    15361 aaaaagagta tgatgattta attcctaata atcaagatgg tgttatagat gaaacataaa
    15421 gattattgga ggaagagatt tgaacaatta gaagaagctc aaaataacaa aagtgtaaaa
    15481 tattatcttg aattagaaaa gcaatataaa ctagctatga atagtataga aaaagatata
    15541 ttagcatggt acaacagatt tgccaaaaat gaaggaatat ctttattaga agctaagaaa
    15601 ctactaaata caagagaact agaagagttt aaatggagtg tagaagaata tattaaatat
    15661 ggtaaagaaa atgctataaa tcaaaagtgg atgaaagagt tagaaaatgc tagtgcaaga
    15721 gttcatataa caaggcttga agctttaaag ttacaaatac agcaacaagt agaagtttta
    15781 tatggaaatg aacttgatgg tattgataaa ctaatgagag atatttatac aagtggatac
    15841 tatcatacag cttttaatgt tcaacaagga gtaaacgttg gttggagttt aatgagtctt
    15901 gatactaata gaataaataa aattatctct aaaccatggg caacagatgg attaaacttc
    15961 agtgaaaggg tttggggtaa gcatagacct gctttagtaa atgaattaca tactaagcta
    16021 actcaatcaa ttattagagg tgaaaatcca aagaaccttg taaatgactt tgctaagaga
    16081 tttaatgtat ctaaatcaca agctaagaat ttaataatga ctgaatcagc tttctttgca
    16141 tcagcaagta gaaaagattg ttttaatgac ttagatgtag agaaatatga gattattgct
    16201 acattagatt taagaacttc aaatatatgc agggagttag atggtaaagt atttgatatg
    16261 aaagattatc aagttgggat aacagctcca ccatttcatt gtcgttgtcg gacaacaaca
    16321 gctccttcgt tcgaggatga agaaggttac agagcagcaa aaggagaaga tggaaaaaca
    16381 tattatgtac catctagtat gaagtataat gagtggtatg agaagtatgt taaaaataat
    16441 agtaaacaaa ctggtggaaa atatactaaa ggtgatatcg agtggaatat aagaagagaa
    16501 gaagaagcag aactatatta caataatatt agaaatagaa aagatgatat ttccaaaata
    16561 gtaaagaata caaattggtc agaaaaaagt ataggtcaaa ttaaaaatca tattttctac
    16621 aatactcata taatgagaga tggaactaga cgtatgttgg attctgacta tagtatgtca
    16681 gttgcttggc aaagacttat aaatggtaca catgaagata ttgatattct cttattaaaa
    16741 catgaatacc ttgaaagtat atttgagaaa aagtataata taagtaactt agaagcccat
    16801 agaatgactg agaaaaagca tgattggtat aaagaattaa ttaaaaagaa aggagagttt
    16861 gaagaagatg attgtcttaa tgaacttatt agaaaagaat aatgaatatg ttatgtatag
    16921 ttatggatat gaagaaaata agcttgatgg aagaataaaa atatatttag atgattttta
    16981 taattatgaa ataataaaag agtcaaaaga tgaacatata agtaaatcag caacgttaaa
    17041 agctatttct aaacttataa aagctgctaa aaataacgat ttgaaaaaag aaatgagtta
    17101 tcaatgttag aagcacttac tgaacaataa attagtaggt gcttttatta tgtaaaagtt
    17161 taagaaaggt aggtaatttt aatgtgtata ttaactcaag ttatagttgt agtttgtgta
    17221 gtacaaatct ttattaattg tattgctaat gtcaatgtag gtattctttg caataaatta
    17281 aaaaaagaaa ataaagctaa tatagataaa gtttctgatg aaattctaaa gaaggtaaaa
    17341 gaagaattaa ataaatcatt agacaaaagt ctttaagggc ttttttatta tgtaaaaaat
    17401 gaaaggagat atttaaaata tggattggtt aaaagaattg ctagaaggaa taaaaataga
    17461 ggataacaag attgatatag cgtctcttca aaaatctata gaaaagaaaa taaaagagac
    17521 tacagttact caagaagatt atacaaatct tgaaacacag cttaatacag ctaatgaaac
    17581 tattaaaaaa tttgaaggag gcatgacaaa agaagatgta gagagtctaa aaacaactta
    17641 tgaaactgat aagaaaactt tggaagaaac ctacaaaaaa gaaattgaag aaaaagactt
    17701 taattactgg ttaaatgatg cttttaagtc tgttaaatgt agagatgaaa tagcattaaa
    17761 agctcattta gacatggaag cactaagaaa tagtaaagat agacaaaaag cttttgaaga
    17821 gcaaataaac cctttgaaac aggataaaga ttatttgttt aatgtaacac tagaaggtga
    17881 agaacccaaa atagatacta taacaccagg gcaagagcct aagataaatg attttggttt
    17941 taattttact ggggtaagac ctcatgaaaa taataataaa taggaggaaa taaaatggca
    18001 gcactaaatt atgcaaaaga atattcaaat gttttagcac aagcatatcc ttatacttta
    18061 aacttcgggg atttatatgc tacagaaaat aatggaagat atagatggac tggttctaaa
    18121 acaatagaaa taccaactat atctacaact ggaagggtag attcaaacag agatacaata
    18181 gcagtagctc aaagaaacta tgataatgct tgggaaccta aggtattaac taatcaaagg
    18241 aaatggtcaa cattagttca tccagctgat ataaaccaaa ctaattatgt ggcttcaatt
    18301 ggtaacatta cgaaggtata taatgaagaa caaaaattcc ctgagatgga tgcttactgt
    18361 atatctaaaa tatatgctga ttggaccgca ttaggtaaca cagcagatac aactgttctt
    18421 acaacagcaa acgtattaga agtatttgat aagttaatgg aaaaaatgac agaagctaga
    18481 gtacctgaaa atggaagaat attgtatgtt actccagtag taaatacact tatcaaaaat
    18541 gcaaaagaga tacaaagaac agtaaacata aaagatggtg gaacttcttt aaatagacaa
    18601 acaactgata ttgatacagt taaaataatt aaagttccat ctaacctcat gaaaactgca
    18661 tatgatttta caactggttg gaaagtagga gcaggagcta agcaaatatt tatgtcttta
    18721 atacatccaa gtgcaataat tacaccagtt tcttatcaat tttctacatt agatgaacca
    18781 agagcagtta cagaaggaaa atatttgtat tttgaagaaa gttttgagga tgtgtttata
    18841 ttaaataaaa aagctgatgc aatacaattt gttgttgaag gagctggagc ataatggcac
    18901 aagtaaggaa attaaataga atattaacta tagaagagtg taaaatagat gatttcttag
    18961 agatgggata tgatttgata gatgaaactg gtaaggcact aaagtatggc aagtcattaa
    19021 atgtaaaaga tttaatagct gaaaataata ttttaaggtc aaaagttgag tctttagaag
    19081 aagaaaataa gcagcttaaa gagaaaaata aacttactaa aaagtaggtg aaaattatgg
    19141 aaaataatag gattgatgat atagaaagaa gacttcaagg atttggatat gttctaaagg
    19201 atggagataa atggttaata gattttgtaa gagaaaaaat agaaaatatt attaaactag
    19261 attgtaatat aggtgaaatt ccaaaagagt tacacaatat agaagtagat atgatagttg
    19321 gagagttttt atttacaaag aaaaatatgg gtcaattaga tatagaaagt cttaattttg
    19381 aagctgtaga aaagtctata tcagaaggtg atacaaaggt agattttgct ataggaagtg
    19441 gctctcaaac accagaacaa cgctttgata gcttagtagc ttatcttact acttatggta
    19501 agaataagat attaaccttt aggtgcttaa gatggtaagt aaaactagaa aagcaataga
    19561 aatgttatat agagataaat gtactatagt tgagtatcag ccaattaaag accctgtaac
    19621 aaaacgaact aacaataaag aagtgattgt attagaaaat caaccatgta aactttcata
    19681 taaaaatata gtttctgcta cagaagggaa agtagctaag ctagagcaaa ctattaaact
    19741 ctttgtatct ccaaatataa gcgttaaagc aggttcaaaa cttattataa ctaatcaaaa
    19801 taatattaca aaagaatata taagaagtgg agaacctgcc atatatccaa accatcaaga
    19861 agtgctattg gaattatgtg aggataaagc ataatggcta gatggggtag tgttgatttt
    19921 agagagttta aaagagcttg taaaaggatg gagaagctta caaagattga tttagataag
    19981 ttttgcaagg atgcagcaag agaattagca gcacgattac ttgggaaagt aattagaaga
    20041 acaccagttg atacaggatt cttaagacaa ggatggaatg gagtggctta tgctaggtcg
    20101 cttcctgtgt ataaacaagg aaataattat attatagaag ttgttaatct gactgaatat
    20161 gcaagttatg taaatttcgg gcatagaact aaagatggaa aaggttgggt taaaggacaa
    20221 catttcttaa ctatttcaga aatggagtta caaggtcaga ttgataagat tatagagaaa
    20281 aaactattaa tattgcttaa aggagtattt gatgcttaat aatataattg atggaatatc
    20341 tattaaatta gataaaacat ttggagagag ttatacaatt tatagtgaag atgtggagca
    20401 aggtataaat gaaccttgtt tttttattgt tcctttaaat ccaagcaaag tatcctatct
    20461 aagtggcagg acattaaaaa agaactcttt tgatgtacat tattttccta aaagtaatga
    20521 taaatcattt gaaataaatg agatagctga gatgttactg gaggaattag agtatataga
    20581 aattgatgga gacttagtca gaggtacaaa tatgaacttt gaaattatag ataatgttct
    20641 tcatttcttt gttgattata actactttac tataaaaagt aatgacacag ataagatgga
    20701 tacagtagag ttattcggtg gtttgaagag aggtgataat tttgagtaaa acattaagca
    20761 aagaagataa ctacaagttt actaaggagc agatagttaa ttctaagaag tatgtaaata
    20821 gaaaagactt attaaatgca attttaaaag aaaatgagtt atattccttc tcagaagtag
    20881 aggaaataat aaataatttt atgaaaggag tgagttagat ggctttaggt ggaggaacat
    20941 ttgtaacaca aaataaggtc ctacctggtg catatataaa ttttgtaagt gctacaaggg
    21001 caaccagttc attatcggat agaggtattg ttgcaatgcc tttagagtta gattggggca
    21061 tagatgaaga agtattccaa gtaaccagtg atgattttga gaagtattca gtgaagtatt
    21121 ttggatatga ttatactcat gagaagctga aaggtttgag agatttattc aaaaatataa
    21181 ggttgggata tttttataaa ttaaataaag gcgttaaagc cagttgtact atagccacag
    21241 caaaatatag tggtatcaga ggaaatgact taaaagtaac agttacaaca aatatagatg
    21301 ataatgctaa gtttgatgtt gtaacacttt tagataataa gaaggtagat attcaagcag
    21361 ctaaagtcat tacagactta caagataatg actatatcac ttggaagaag gatgcaacac
    21421 tagaagcaag cgcaggactt gtatttactg gtggaactaa tggcgaagct gtgacaggag
    21481 cagagtacca agctttcttg gataaaatag aaagctatag ctttaatgct ttaggatgtt
    21541 tggctataac aacagaaatt aaaagtttat ttgtagaatt tacaaagaga atgagagata
    21601 aggtaggagc taagtttcaa acagtactat ataagaaaag tgatgcagat tatgaagggg
    21661 tagtgtctgt agaaaataag attaaagata ctgggttatt agaatctagt ttagtttatt
    21721 gggctactgg agctatagca ggatgcgata taaataaatc taatactaat aaaaaatatg
    21781 atggtgagtt tgatgttgat gtaaattaca ctcaaataca gttagaagaa gctttaaaaa
    21841 ctggtaaatt tatattccat aaagttggtg atgaagttca tgtattagag gatataaata
    21901 cttttgttag ttttacagat gaaaagaatg acgacttttc aagtaatcaa agtgttagag
    21961 tacttgacca gattgctaat gatatagcga ctttatttaa tgaaaagtac ttaggtaaag
    22021 ttccaaatga caaagcagga agaataagct tttggaatga tgtagtaaaa caccataaag
    22081 aattagaaaa cattagagca atagaagatt ttaaaactga tgatgttagt gtggagcttg
    22141 gaaatgacaa gaaaacagtt atagtgagtg atgcggttaa ggttataaat gctatgagta
    22201 agctttatat gactgtttca gttagttaat taggaaggag aatattagaa tggctaaaaa
    22261 tattactatg aagtcaaaag atgcaataag tgcatctttg gcagaatgct atgttaccat
    22321 tgaaggtaaa agataccttc ttatgcagtg tatcaaggta gaggctaaat ttaagaagaa
    22381 taaaagtaag ataccaattt tagggcaaac aggaaaagga aacaaaacta ctggatggga
    22441 aggcacagga agtgcaactg ttcattataa tacttctatc tttagaaaac ttatgcttag
    22501 atataaggaa actggagaag atatatattt cgatatgcaa attactaatg aagacccaac
    22561 aagttcagta ggtcgtcaaa ctattatatt aaaagattgc aatatggatg aggttacatt
    22621 agctaaattt gatgcagata gtgaatattt agatgaggat atagatttta cttttgatga
    22681 ttgggatatg ccagaagaat ttaaaatttt attaggtatg atatagaata cacatttata
    22741 aattatagat gtgtgttttt tatgtaaaaa ttaaaataaa aggagaatta agaaatgagt
    22801 aatttaagtg cttttttaag tcaaaatgca ataaaaaatg agaatgtaat gtatgtggca
    22861 agcgatagat ttttagacga agaaggaaag ccagttgaat gggaattaag agttttatct
    22921 tctgaggaag atgaagtatt aagaagaaac tgtaccaaaa gagtaaaagt tattggcaat
    22981 aatggtaagc atactggtca atatactagt gaaattgact ataacagcta tgtagctgaa
    23041 ttatgtgtag catctacagt atttccagat ttgaaagatg tggaacttca aaatagttat
    23101 ggagtaatgg gagaagctca gttattaaag acaatgctta cagcaggtga gtatgtcaat
    23161 tatacagtaa aagttaacga ggttaatgga tttgatacat cttttgagga taaagtagaa
    23221 gaagcaaaaa actaattcga ggtggcgact ttgatgctag tataacccat tattgtattc
    23281 aaaaattaaa gtggaagcca agtgactata tgggattaga aattaatgag agagcattag
    23341 ccgccgcctc catattggta aaaatagaag atgaagaaga agcaatgaaa gaagctgaaa
    23401 gagaaagaaa aagaggtaga agaagataga aaaatataaa ataaatgtat agtaggtaaa
    23461 atatgtaaga attatatgtt ataataattg tagcaagaag atgtaatcta caatttatag
    23521 agtggagttc atacaaaaga ttatcctccc aacgtataga agggaggtga atatgtatgg
    23581 ataatttttt acaaggtgta ctagcaagtt tagttgccag tttaatagtt tacttaacta
    23641 gtaagttatt taaaaaagta aaaagccact caaacacgac taagagtgac tttgatttta
    23701 aacttacaat caagtttaaa agaaataaac attaattttt agaacttcac tctagtttca
    23761 aatagattgt agttcttctt gctattatta taccacaaat tggtacagat attcaaaaat
    23821 aatattttta tgatataata aaaatgtaaa gattttgcag tgttcgattt ttgtaataaa
    23881 atatggcttg acaattggaa tacaaggcat tgagggtgtg tgataaatgt tatcaattgc
    23941 actactcatg gttcactgca attttaagag tattgtatat atgtaggtat tggaaatgct
    24001 aagtttattt tggggtttta gattaactat atggaatgta aatgcataat ttagataacc
    24061 ttttatatca tcaatataag gttttagatt aactatatgg aatgtaaatt gaattgggca
    24121 agggacattc cctttttgag ttgtagtttt agattaacta tatggaatgt aaatatctcc
    24181 atctttggca ctatccatac taatatattt gttttagatt aactatatgg aatgtaaatg
    24241 tctatagtca tcccaacttt atcacttaaa ttatctagtt ttagattaac tatatggaat
    24301 gtaaatatta attggcgaga taagtggcaa gagttttata agggttttag attaactata
    24361 tggaatgtaa atggatgtta cacatgtgca aactcaacag aggaagcctg ttttagatta
    24421 actatatgga atgtaaattt cgcaacttat gatggtgaaa tgattacatt aacaggtttt
    24481 atattaacta tgtggtatat aaagattact ctaaaagtct ttttatcatt ttctacctca
    24541 attttatatt aactatgtgg tatgtaaata aagcaaaaga taggaatgat aattttaaaa
    24601 ctccagactt ttatattaac aatgtggaga aaaactaaat agaagaaaga agcacttatt
    24661 tttggtaggt gcttttgttt tgctcaaatt tggtcggttg agtaaaataa ttagaaaaaa
    24721 ttgggataag ttattgactt ttgtctgccg aaactatata atataattaa ggcagacaaa
    24781 agtgaggtga agatatgcca agtaaaaaaa taggtagacc tacagataat cctaaaggca
    24841 gtagaataac tataagatta gatgaagaat ctaaaaatat tctagaaaaa tactgtgaaa
    24901 aagaagatat agacaaagcc gaaggagtta gaagaggtat aaaactacta aaagacaaat
    24961 aaaaagtagc ccaaccgccg accaaagcaa aatggactac ttaacctaga gttatctcta
    25021 tatgaaatat tctatcatgt aaagataact ctttcaagat aataaatcga aagggtgatt
    25081 tttgtatgaa taatgaattg atgaattttg aaaataatga attaggaata aaagtgagaa
    25141 ctattaaata tgaagatgga agtataggaa ttaatgcaga agacgcagct agaggatttg
    25201 ggtggattac cattgccaca agtggcaacg aaacaattag atggtcaaga atgaatgaat
    25261 attgtaaaga ttttggtttc ctcaacttgt tggggaaaga tgattatata cctgaatcat
    25321 tattttatct tttaggtatg aaagctaaaa atgaaacggc agtaaaattt caaacatggt
    25381 tagcagtaga tgtactacca tcaataagac aaactggtgc atacataaca aataatgcta
    25441 atcccgagaa gttgagagaa aaagcaagtg agattgaaaa gttacagttg gcttataaca
    25501 gcacatctat gttaaaagaa ctattagatg atgcaggatt tgacaacaaa tcaaaactat
    25561 taacagctaa aacattatat aagaaagcag gtattgattt accaatagag atagatgaag
    25621 aagagcatta ttttgataca aagcaaatag cgtctaaact gaaaatatat tctaagagta
    25681 ataaaccagc acaattggct atttgtgaga ttattaaaaa gattgattta gaagaaaatg
    25741 aagttaaggg agtttgggaa acgaatggaa gttggactgg tactgtaaat aaatatacag
    25801 aaagtgtaat aaacaagatt aagtgttgga tagatgaaaa taacaagcct acaaagatac
    25861 aaggtgagaa gaagaatttc catgtagtgt ataaaattga gtaaatttat cagtcgtatt
    25921 aaataattta gtttattttt agggggatta atacaatgcg tgaaagttta cttaatgaat
    25981 ataatttaaa aactgatgaa gatgtagaat attttgtgaa atttgctaat gcgttatatg
    26041 aactaaaaca gaatagtgaa gaaaaatttc aagagtatgc agagatacta agaggtattc
    26101 ttagagagca agaagagaga aaaaataaat aaaataatat ggataaagca cttggatatt
    26161 cttttgtttc aagtgctttg tctgttaaaa aatggtataa tataggtaag agttatatta
    26221 acaatgtggt atgtaaattt tctaaatggt gctggaatag atgaaaaggc aaagtgtttt
    26281 atattaacaa tgtggtatgt aaattgtctt attttattat taaagttttc ttgttcattt
    26341 gtgtcttata ttaactaagt ggtatgtaaa gtgactttca tatgctcttt tatcagcttc
    26401 tgacataagt tttatattaa ctaagtggta tgtaaagctt tgtgcaagtt ctgccccaag
    26461 tcgattgaac tcagatttta tattaacaat gtggtatgta aagatagaat gggaacttaa
    26521 agcaatagat tcagacagaa ttttatatta actatgtggt atgtaaagaa tggagctata
    26581 gtagacagca ttgatacaaa tattatttta tattaactaa gtggtatgta aagttgacca
    26641 attgctttaa aattaagttc tctagcatca ttttatatta actatgtggt atgtaaagaa
    26701 cacagtatca aatgcactcg caatacttct tatgggtttt atattaacta tgtggactta
    26761 aaattaaaaa taattcaaaa acacttacaa atgagtaagt gtttttttaa tgaaaggagg
    26821 tgataataat gtaaaaattt tactaatata gtataatatt gttaaagaat ataatttagg
    26881 gggatattat attatgaaga aaaaagtatg ttttttattt tctattctta tagttatctg
    26941 tttagctatt gtaggatgtt ctaattcaga aagtccagag gagagtagta aaaataatga
    27001 accaaaaaaa gaagaaaaaa aggataaaga agtagtcata ggagagaaaa ttatttcaga
    27061 taaaatggaa atcactatta ataatattga attctcttat gatgttttac caaaggttaa
    27121 ggaaagttta tatacacatt atcctgctga gtcaggcaaa gtatatattg atattgctgc
    27181 tgatataaaa aatactcaaa aacaagagtt aaattgttca gatttactaa ctattgaagc
    27241 aaattataat gatgggtata aatattcatc acaaacaata gtagaagatg aaaccacagg
    27301 ttttacttat gataatattt ctagtattga ccctttagaa acaaagggag ttagatttat
    27361 aatcgattgc cctgatgaag taaaaacaag tgataagcca gtaatattaa gttttacatt
    27421 tgatgggaat aagtatgttt ataaaatgaa gtaatttata caaaaatgaa tatattataa
    27481 taccaaggag atattttatg gatgatatag tagaatatat attttgtagc gagtgtggag
    27541 caaagtgttt aaaaggaagc aagttttgca gtgaatgtgg aacggaaata gctgatataa
    27601 aaatgttaaa tgaaagcatt attaaagaaa aggaatatga tttgaagggt attgatttac
    27661 aacatgtaat gcaagaaaca agttttataa aagcttcatc tgtaagaaga ttgaaagaat
    27721 taactggaat agagttggat gattgtagaa aaatattaga agaaccatat caaaaatatt
    27781 ataatgaaaa tgctgatatg cttgaagaaa aaagaaaaaa agaagatgat atatcaaaaa
    27841 ttagaaaagc caaagaggaa aagaaagaaa aagaaaaaat agcttgttgc cctgcatgtg
    27901 gttcaacttc tttgacaaca cataaaaaag gttttggcat aggaaaagct ataacaggag
    27961 ctactatagc aggaggcatt ggtctcgtag caggaaacat aggagcaaag aaagttagag
    28021 ttacatgctt gaactgtggg aaacagtttt gggcaggcaa aaaatagata ctaaaaataa
    28081 aacacttact caggtaggtg tttttttaat gaaagaaggt gatgataatg taaaaatttt
    28141 acttatatag tataataatc ttataaaatt gcgtaggggg taatattatg ggattatttg
    28201 gaggtaaaga accatgttgc atatgtggag gaaagggtaa aaataaagtt ttagaaaatg
    28261 aatatctgtg caataattgc tttgttgatt ttacgatatt ctctagtgga agattaaaaa
    28321 caactagtgc aatgcaagta ttagcagacc atgaaggaat aagaaagttt ataaattttt
    28381 ctaagaaaaa tagagaacta ttagaaaaat ttgttgagac aaataaaatt aataaattca
    28441 tatcaattga tgaaaataat aaatttatta aaatatcaga tattcgtaaa ggcggagata
    28501 taatagaaac cgtatatgca actgatgaaa ttatagagtt tgaactttta gaagatgaag
    28561 agtctatagt tagtggtggt ttaggaagag ctgtagttgg gggtgcttta tttggtgcaa
    28621 ctggagctgt agttggaggt gtaacaggta aaaaaacaac aagaaagatt gtcaatacat
    28681 ttaaaatcaa aataacattt aataatatta ataatccttt agaatatatt aatttgatta
    28741 atacaaggac aaaaactaat tcatctatat accaaaatgc ttgtaatgaa gcacaagaga
    28801 ttttatcagt actttcaata attgtaaaaa acaatgataa agctaacaat gaacaagata
    28861 aaactagtag ttcaatagag caagtaaaag gattgaaaga gctactagat ataggagcaa
    28921 taacagaaga agaatttaat actaagaaaa aagaattatt aaatttataa taactagaca
    28981 cttacaaaag taagtgtttt tttatatgga aatttatgaa aggagagtga taaaatggca
    29041 actatacaaa catctatccg aattttcgat ggaatgacac ctgcatttag gagtatgaca
    29101 gcatctatta atacgacaat taatagtcta gaaagactac aagggagatt gaataatccg
    29161 ctcaatacag gtggaataca gacatctcat cagagtttaa ataacataga aaatatttta
    29221 acaagaatag aacaaaacat aggaaaagca gatgaacaac aaagaaagtt taacgaggat
    29281 attaataaag gagcaagtaa tacagataga ttattaggaa gtgttaaaaa ggttgttggg
    29341 acttatatgg gattaaagac gataggagga ttagcaaatt taagtgacca aatgacgagt
    29401 acaaatgccc gtttaaacat gataaatgat ggtcaacttt ctgacggagg attgaataaa
    29461 atgattttcc agtcggctga aaggtcaaga gcatcctatc tagacacagc acagatagta
    29521 agccgtatag gtatgaatgc agggagtgca tttagtagta ctagagaaat agtaagcttt
    29581 gcagagcagc tcaacaaaaa atttgtaata gcaggtgcaa gtactgagga aatgaactcg
    29641 gcacttttac agttgactca aggattagga agtggagttt tgcgtgggga agaattaaat
    29701 gctgtatttg agtcagcacc taatatcatc aaaagtattg cggattattt agatgtggac
    29761 ataggaaaga ttcgaggaat ggcaagcgag ggaatgttga cagcagatat tgtaaaaaat
    29821 tctctgcttg cagcatcagc agaaacaaat gctcaatttg aaaaaatgcc acttacaata
    29881 ggtcaaatct ttacatcaat taagaataac gcagtaatga tatttggagc gatacaaaaa
    29941 aagattgagg atacagtttc aagcggagga tttcgaacct tcatagttaa tgtaacagat
    30001 tcgttgtatg tcttgggagc tgttggatat agtgtcttta atgggtttat tgatttgctg
    30061 agcagtccaa catttcaagg ttttgcaaat atgatgattg tcggaatcag tttaattact
    30121 caaggatttg ggtggctatt aacagtatta ggaagtgtta ttaattttat ttcacaaggt
    30181 tggagtataa tacaacctat tttgataacg agcatcgttt tgtggggctt atataaaaca
    30241 gctgtcatag caggtgcttt agttacagct attcaggtag tgtggatagc tttacagaca
    30301 ttttggacta atttgctaaa tggttcgtta ttaactaata taatgatgaa tatagctgca
    30361 aaaatatcaa cagatgcact aagtggttca atgttacttt taattaccac aatagttatg
    30421 gttgtagcag cagtagcctt agtaatagca gcaatatttg tagcagtagc aatatttaac
    30481 cattttgcag gaacaagcat ttctgcaact ggagtagttg taggagcttt ctattttcta
    30541 ggaacttgca tttatgatgt attcgcagga gcgtggaaca tagttatggc atttgcagag
    30601 ttctttgtta attcatttaa tatcgttatc tacaatgtgc agttattatt ttataaattc
    30661 caaaactttg taataaatgc catgggagat gtaggaggaa gttttgacaa ttgtgctaca
    30721 gctttagcaa atgcttttgt aagtgctgct aatatagcaa taaaaggtat aaatggagtt
    30781 ataaaaacac taaatttgat accaggcgtt aatataaaga catttggaag cttggacaaa
    30841 atagattctt ttgtaaaaca atataaagat taccaaaaaa cgttaaaaga gcctgtaaag
    30901 cctgctgaat ggaaagctcc aactatgaaa ttgaagaatc ctgtagattc atttaaaaaa
    30961 gggtatgaag taggtcaaaa tttagaaaat aaaataaaag atgcttttga cattagcaag
    31021 atagcagaaa aggcaaaaaa agatttagga ctagatgacc tttgggatga taaatatgga
    31081 ttaggagata gatttggttc agcaggtctt aattcacctt taaatgacgc agcaaaaaat
    31141 gtaaaagaca cagcaggaaa cacagccaaa atggctaaaa caatggataa aagtcaagaa
    31201 gaccttaaat acttaagaga cattgcagaa caagaaacaa taaaccgttt tacaggagtc
    31261 aacattaaaa ttgacatgaa caatacaaac aacataagta aagatgcaga tgttgatgga
    31321 atagttaatg tcttaactga aaaactgaat gatgcaatgg ttgtatcagc ggaaggaata
    31381 gtttaggagg tgtttgaatg gcttatgatt tttatttaga tggagtacaa ttaccaatcg
    31441 caccacccaa gcttgaagtc aaagtgacaa ataaaaacaa gacagttgat ttaataaatg
    31501 ttggagaagt aaacatatta aaaaaagaag gattatctga aataagtttt gaagcagaat
    31561 ttacacataa taaactacca ttttatcgag ggacttttaa agatgttcaa ttctttttaa
    31621 gtaagctaga attactaaaa actgattgta agccatttca atttattgtc tcgagggaaa
    31681 tgggtggaaa agtactattt aacactaata tgaaagtgtc attagaagaa tataacatag
    31741 tagaagatgc agagaatgcc tcagatacaa aagttgcaat aaagttaaaa caatacagag
    31801 attactcaac taaaaagtta gttcttgccc ctcctaaaaa tgagactggt agacctaatg
    31861 taaagataga gccaaaacga gttgattcag tcaatgcacc aagtaataag acatatacag
    31921 tcaaaagtgg tgattctctt tggtcaattt gtcagaaaca acttggtaat ggttcactgt
    31981 ataagaaggt atatgaatta aataaatcta tgatggataa ggcaaataag gggaagaatt
    32041 taagtaaata caccatctac aaagggcagg tgttaaaact tggctgatga attagtgtta
    32101 gcaaatgata gagatgtaag attagtcata gcacattggg aagatttcta tgaacctacc
    32161 gttttagatg gaataacatg ggaaattgaa aggcgaggaa caccttcaaa gttagaattt
    32221 acaatagtca tggatgatat actgcaattt tgtgaaggta attcagttcg tttatatttt
    32281 aaaggaatag gcatatttta tggatatata tttcaaaaga aaagagataa agaaaatcac
    32341 attaaaattg ttgcttacga ccagctaaga tattttaaga ataaagatac ttatgtatat
    32401 agtaataaaa ctgcaagtga acttataaaa atgttggcta aagattttaa tttaaaatac
    32461 aatgtcatag aagatactaa gtataaacta tctagagtcg aagaaaataa aacactcttt
    32521 gacatgatac taacagcact agatgatact ctaagagaga aaaaagaaat gtataccttg
    32581 tatgatgatt ttggaagaat aacattaaag aatgttgcat caatgaaact ggatactgtc
    32641 atgaacaatg atgtcataga ggactttgac tataattcaa gtatagatag tgatacttat
    32701 acaaaaatca aacttgtaag agacaacgag gagtcaggaa aaagagatgt gtatattgct
    32761 caagactcta cacatatgag gagttgggga atacttcaaa tgtttgagac agttgataaa
    32821 aatatgaatg aagcagagat aaaacaaaag tgtgatatac ttctaaaact atataataag
    32881 aaaactaagt cattaagttt aaaaaatgca cttggagata ttagagtgag agcaggttgt
    32941 ttagtacctg tttttttaaa tctaggagat attaaacttc aaaattatat gttagttgag
    33001 aaagtaaaac atacatttga gaataattcg cactttatgg atttgactct tgttgatgga
    33061 gatgaatttg cttcttattc ttcaagctca tatagtagtg gaaatactaa caataaggat
    33121 gaaaagaaaa atggtcctgc acaaagtact acgaaaaaaa atacaggtaa aaaagttcct
    33181 gctatattta ctgcatatta tccaggaaac aatgcaatgg aaggtggaaa aacagattgc
    33241 aatggaaagc cacttgatgt aaaatcaaga actgttgctg gtccaatgaa tcgagaagga
    33301 gttaagaaaa cttggtatac tgatgatttt ctaaagaaac atccagtttt tgaatatgga
    33361 gataaagtaa aaattatact tcctggtact gcctatgaca acaaagtata tacagttaaa
    33421 gataatggag gaagaatata tgttgaaaca aacggaacat atcatataga tatactatta
    33481 gctaatgcta gtgaatgtaa aaaatttggt agaaagaatg gctatataat tataggtgga
    33541 gatgaagaac aaacatatca agttgaaggt aataaccaaa gtagtacaaa taataactct
    33601 aaagaagata aattaattag tatagcaaaa agtaaactgg gttgtaatta tgtgtatgga
    33661 gcagaaggtc ctaataattt tgattgcagt gggtttactc aatggtgtta taaacaaata
    33721 ggtataaaaa ttcctcgtac tgcttctgca caaagtaaag caggaaaagc agtagattta
    33781 aaagatagaa gcaagtggaa agcaggagac ttattatgta gaattggtgg aggaagtagt
    33841 aatcatgttg taatgtacat tggaaacaat caaataattc attcaccaca aacaggagat
    33901 gtggtaaaaa tagagtctgt taattcttat agaaaaggaa aagcatacac acatgtgaga
    33961 agatttatat aagtgaggtg gcaatatgag ccaagattta ttacagataa taaaaaaagc
    34021 tgcaatggat gcagtagaaa caagcaaccc aatgagggtt gtatttggaa caatagaaag
    34081 tattagtcct ctaagagtta agatagaaca aaaactatct attggtgaaa tttttctaat
    34141 acaaacagat acatttaaaa gatatacaga taaaaaaata ggagataaat tagtcttaat
    34201 tcgtatgcaa ggagggcaac aatacttgat tttagatagg atgtgataaa gtgttaccaa
    34261 gtgataattt agattatgat attgaagatg tatcaataat taattttgat gtaagacaag
    34321 agccaagtaa gacatttaaa cttcatatag aaaagtctaa gattgatggt atttgtgatg
    34381 atgtagaagc attaaaacaa accatctttt taattttaaa cacagagaga taccaacatc
    34441 taatatatag ttggaattat ggagtcgagt tgaacgacct tattggagag cctatatcct
    34501 ttgtaatccc cgaacttgga agacgaatca aagaagcact aattcaagat gataggattg
    34561 aaaatgtaga taattttgag tttcaaaata taaagggtaa actacaatgt agattttcag
    34621 ttcatacaaa atatggaaat ataaaagcag agaaggtggt gagtgtataa ttgtttgagt
    34681 taatgacatt tgaaaacata attaaaagaa tgttagatag tgtaccagat acttttgata
    34741 aaagggaagg ttctataata tataatgctc ttgctcctgt tgctatagaa cttacagaaa
    34801 catacattgc aatggatgaa ttactagacc aaacattcgt agatactgct agttattact
    34861 atttagagaa gagatgtaaa gagagaggta ttacaccttt acctgcaacc aatacaattg
    34921 caaaaggagt ttttaatata gatattccta ttgattcaag attcaactta ggagagtata
    34981 actatgtagc aattgagaga atatctgaag gtatatataa gatgaaatgt gaaactgctg
    35041 gacctatttt tgaacttggt cagttgattc caattgaata tataaacggt cttgaaacag
    35101 cagagttaac agaaatactg ataaatggag aagatgaaga atcagaagac agtttaaggc
    35161 aacgatatta tgatagtcta aattctcaat cttttggggg taatatacaa aactataaag
    35221 atgaagttaa caaaatacaa gatgttggag gagttaaagt ttatcctgtt tggaacggtg
    35281 gaggaactgt taagttagta ataattaatt ctaatttcaa agtaccaagc actgacttag
    35341 ttaatttagt gcaagaagaa attgaccctt tacaaaacca aggagaaggt cttggattag
    35401 caccaattgg acaccgagtc acagttgaag gagttacaag tacaactata aatatatcag
    35461 cagagataac atacaaaaat ggctacactt gggagaatat aaaatcaatt gcagaagaag
    35521 caatagacga ctatttaaat gaacttaaca tgagttggga agatgaagaa aacttaatag
    35581 tccgtatatc tcaaattgaa actagattac ttagtattga tggagtgtta gatattacaa
    35641 acacaatgat aaatgaggtt aaatctaatc taacaataga tagtaacagc atagtagtga
    35701 gaggtgaggt agttggataa agagattaat ctaataaatt acttaccaca aattctacaa
    35761 gataaagaag aatatataaa agtatttaat gtaggaaata aagaaataaa aatattacat
    35821 gataaattaa aggacctatc aaatgaccag tttttagagg acctaactat aagtggtata
    35881 aaaagatggg aaaagataat gtctataact cctaaaagta atgagagttt agaagataga
    35941 aggtttagga tttttagtaa atatataagt aaattacctt actcagagag atttttaagg
    36001 aattggctag atagtatagt tggagaaggt aattatgagt taactataaa taatgctact
    36061 tataatatac atttagaaag tgatgctaga aatcaagatt ggtttgagga agttcattct
    36121 tttgtaagta acattaagcc atgcaacatg acactagatt acactagagt gcttataagc
    36181 aaagacaatt atatgaattt tggtataaca accttaatgg gtcaagaaat aactatatac
    36241 ccttggagtc caccagatat agaaacttat ggagaaattg atgtattaac tggcaatgga
    36301 gttggatacc aagaggtaac aatattttag gaggtgatat attggctata gataaaagtt
    36361 attacactat aattacagat gtagggaaag caaagatagc aaatgcaagt gtcacaggta
    36421 ataaagtggg atttgtaaaa attcaacttg gtgatggagg agggagtgaa tatactccaa
    36481 ctgagagtca gacagctctc aaaaacgtgg tatgggaagg caatattgga aatacaacta
    36541 cagatgaaac tgcaccaaat tgtataatat tagagagttt aataccatca agtgtaggcg
    36601 gatttatgat aagagaaata ggatatttag atgatgaaaa taatttaatt gccatttcta
    36661 aatacaaaga gtgttataaa ccttctatag aacaaggtgc agtggtagac atgaaggtta
    36721 aaactgtgct tattgtatct aatgtaaata atatagaact taaaattgac ccaacaataa
    36781 tctttgcaac actcaaagat atacaagact tagaaactaa aataggtact gttaatacta
    36841 aaattgatac aactaaaaca gaattaacaa gcaacataga aactgctaaa acagaaattg
    36901 acgagaaaat aggggataca acacaactta ctacaacaga taaaacaaat atagttggtg
    36961 cattaaatga ggtaaaaact agtgtagata gcatagaaac aacggcagag aaaacaagtt
    37021 ataataatgc aacaagtaat cttgctgcta cgaatgtgca aggggcaata gatgaagttg
    37081 ttagaaaaat agaaaaattt aatgaggtta atatatctat acaaaatgat atgttaccta
    37141 tttaagagag gagagtgaga aaatgcagac tgaatgggat tttaattatg ctaattatgt
    37201 acaaaatgtt tcattgctac ctgggcgata taaattagaa tgttggggtg cttgtggtgg
    37261 tactcttggt gcaagtgatt ggactgaatg tgcaaaaggc ggttattcaa aaggcgaagt
    37321 tatattaaaa aaaagaacta acttatgtat ctgtgttggt caatcgggtt atgaaaaact
    37381 tgatactggt tcaactctta ccagaactgg atttaatggg ggaggacgaa caaatgcaca
    37441 tagtattaat ggcaattatt attctaaata cggtggtgga gcaaccgata taagagctta
    37501 ttatactaga gcgacttggg atagtgcaga aggtttactt tcgcgtatac ttgttgcagg
    37561 tggtggtgga ggtatgaaaa ataattttgc ttctgctcgt tctattggtc atggtggtgg
    37621 ttatgtaggt gaaaatggaa ttggtcgtga cagagatttt tgtggtggtg gttctcaata
    37681 ccaaggtgga acaagttacg atacagaaga ataccatggt tcgttaggga aaggaggtta
    37741 tggtggaata ggagtaggtg gaggtggtgg ttggcacggt ggtgctggtt cttattctaa
    37801 tgaatgtgga ggtggtggaa gtggttacgc actaactaaa gatagttata agccacctgg
    37861 atatatacca acatctgaat attggctaga aaatgtagtt atgactactg gaggtaatac
    37921 tactagagca gatggctacg ctaaaataac attactacaa gcattaccat ttttaaatat
    37981 atcatcatat aactcaacta ctgcaacgtt taaagctgat cacacagacc ctacactact
    38041 aactaaaata gaatatttta tagatgacac attaaaagaa actataacaa cagatttaac
    38101 tcttgaaaaa acaattaact atacattaga agataacgcc ctacacacac ttaagatagt
    38161 tgtcacagac agtgctaatg ctacagcaga aaaaaatgta agtataagca aaggaattgc
    38221 acctctccct gctggttcta caacagatga agttacaagc aaatggatgg aaattaaaga
    38281 tacattcaaa agtggcaaaa caagtattat aaatacttta gcattaaaga atatagacgc
    38341 aagtttaaat aatacacttg ttgagttatc agagaaaatt aaaacgagtt ttgatagttc
    38401 agacgctagt gttgaggatt taacaaacaa attgacacaa gctaataata ctatatcaca
    38461 gttaaataca aaatataaat ttgcatatag tttggatttg acagttcact ggtttattga
    38521 ttgtggattt aagcctgatt ttgttattta tgaatgtata aataatcatg gtaaatttct
    38581 tgttttctta actcctttta attattctgt atttgatatt ggaaatttag gttggacaat
    38641 tacagcaaga gaagatataa gcaagaaaga ttctttttct ataaataaca taaatcaatt
    38701 ttggggaaca aagattagag atacaggatt taataatgca gatatgccaa aagatagttt
    38761 aaatgataga tatgtttttt ggatagcaat taaatgttta taggaggttt aatatatgaa
    38821 aaatatagga agaatagttt tttatgataa tgatacaggg gatatattaa tgttttatgg
    38881 agaaaaaaca gtaagtgaca gtatagatat taatatccct aagatagatt ctattgagtt
    38941 gccatatgga agtatagatt atactagaaa taggctaata ggtataaatg tagaaacaaa
    39001 agaaccaatt ctggaagaaa taccagtata tgtaagtgaa gaagaaaaaa gaatacaaga
    39061 attagaaaat caaatattga ttgcagaaaa cgaaaaagta ggaggattat tataatgaat
    39121 ataaataatg ttgtagtaag aatattagca gagaggattt tgaataaagg attaaatccc
    39181 ttaaaaaata gagagtttca acttgatgat gtaactaatg cagagtacag aaaagcagta
    39241 gaggattata ttatagagca tagtggagta gtagaaggag cagaaccaac aaaataggtt
    39301 ctttttttat ttcaattaat taggaggctt acatgaatga agaactgttc gaagcagatt
    39361 taaaaagaca tgaaacaaga ataaataagc atggagaaga aatagacgaa ttaaagatag
    39421 caaatataga gtctaaagca gaattaaaag cattgtgtga gaatctaaac tcacttacaa
    39481 gtatgctcaa atggctaatt ggaacaatga ttacaacact tataggtttc tttatatttg
    39541 caatacaaag aggaatattt taattaatta ggaggttaaa agatggataa tttaataagt
    39601 tttataccag agcagttgct aattttagta gctgctcttt atgttatagg agcaggttgc
    39661 aaaaaatata aacaactaga taataagtat attccagtag tgttattagc acttggaata
    39721 ggattttcaa tatggatgtt aggactaaat gctgattcag tactgcaagg tgtaatttgt
    39781 tggggaatat caataggtat aaatcaaact tacaaacaat taaaggagga aaataaataa
    39841 tgaaaatagg tgtaaattgt ggacatacaa agacaggggc aggaagtgga gctataggga
    39901 aaataaatga atcaatagaa actagaaatg taggatataa agtaatagat aaattaaaaa
    39961 ctctaggtaa caatgtagtt gattgtacta tagataaagc atctacacaa agtgagtgtt
    40021 tgtctaaaat agcaacacaa gcaaatagac aagatttaga ttggtttata agcatacatt
    40081 ttaatgcagg aaaaggacga ggatgcgaag tttacacata caaaggcaaa cagtatcaag
    40141 atgctataga cgtttgtaaa aaaatctctg atttaggatt tacaaatcga ggggtaaaag
    40201 atggaagtgg attatatgta gtaaagaaaa caaaagctaa aagtatgcta atagaagtat
    40261 gctttgtgga cagtgaagat gcaaataagt atttgagttt aggagctgat aaattagcta
    40321 ctgcaatagt agaagctata actaaacata taagttcagc agaagaaaac aattataata
    40381 gatataaaca tacaatagtg tacagtggtg atgataaagt atcggcagac attttaggat
    40441 tatattataa gagagaaaaa gaaagttatt tagttacaga tataaaagac tataaaccac
    40501 atagaacaca aaatttgtat gtaattggtg gagtaacttg taataaaatg aaggaaatga
    40561 gtaagactac aggagaaaaa tttactcaac tatatggtaa tgatgtatgg tcaacaatgg
    40621 ataaagctat agaatttgta aaagaaaaat tgtagagtta aaggtgagaa tatgttaata
    40681 caagagaaaa gtttttatcc aaacgatatt taccccaaaa tagactttct caaaataaaa
    40741 aggcagttaa aatcaatata caagaatgat ttatcagact gtgggagcat atgtataata
    40801 gaaagaaaag actattcttt aagtgtaaat agcataggtg aagtgaatat atactatgat
    40861 ttaaagttta agcaatgtgt tcaagatgca gtaaaagaca ttgaattaat gtttaaaagt
    40921 caaattagaa gtttttattt gatagataga ttagaaggta gcaactagtt agttgttacc
    40981 tcctttttta cacctcaatt aaaacagttt ttataaaaga tagtatttta caaataagta
    41041 aaattgataa ttcaagttaa agatatttac ttacattttg cctacacttt atatacaatt
    41101 tctagactat tttgtaattc acataatata tattaaatgt aatatatatt atatgaaaat
    41161 aacaaggtat ataattacat gtaaaaaatg tattaaattg ataatgatta ttatatactg
    41221 gttaattatt aatacaaagg gtattacaaa tataaaggat atcaaaattg ttcagaaaag
    41281 agtatagtat gagaaaatat taaactttaa tgaaaaaagt aacatgttta tataatcata
    41341 aaaataaaaa tatatagagc agatgtataa aaacttagta tatatgagaa aatattaata
    41401 atatttgttg ttggaatgta aatattaaaa tggtataatt taggtaacaa atcttaaatt
    41461 atactcttgg aggtatattt atggaaagat ttgtttacaa gggggaattt aatatgaata
    41521 attattcaat tatgtttgaa aataagtcta ttttagattt aaaacaaaca tgctatttag
    41581 atagcttata taatttattt gaagaaaaaa ttcagtatgt aactaaaact ctaaaaaata
    41641 acaatataga agaggatgaa tgggatatac agtttataaa agaagatgcc ttgcagtcaa
    41701 ttaaaaatat agaagaagat tttattactg ataaaacatt agattggaga atcaatttat
    41761 caaaaataat aaagaaagta ttagataaaa gcaaggctaa ctttaaaata gcagatgaaa
    41821 tgtatcataa tcctatgaag aaaagtgaac agtattatga tttattaagt aatatctttg
    41881 ataatttaga agagcttata tgtataaaat ataaagaata cgaaatttct agaaatatca
    41941 ggtttactaa tattggaaat ttagttaaca atgataactc atcaaattat atagacaatg
    42001 aacatattga atttgatttt aactttaagt ttgaaataga ggattatgat aatgatgatt
    42061 atgcattggc agcttagatt ttggaggaag attaatggaa ttagataaaa tgaagtatag
    42121 aaaattagtt aatgatgtgg aactagtaaa tgtgctaatt aaaaatattg aattaagtga
    42181 tgttatatta cataaagatg aaaatatcaa aaatgaaagt attaaatgtg atgttaatat
    42241 gaaatatgag tgtgaagaat ttaaaaaatt atcagaagta gtagaatttt atcctaaatt
    42301 taacttaaga atagaatgtc aaggagaagg tttggtaaat ttaaaatttg aactaagggc
    42361 aatttataaa tttaattcaa tagaggatta tgaagatgat tatatattaa tgtttataga
    42421 acgaaatgtt ccagttaata tatggcctta tgcaagagag ataataagtt ccatcacaac
    42481 tcgtattgga tatcctgctc tagtaatttc tccatataag gcataatatg agattgaaat
    42541 ttaaatctaa agagagtact agcagggaaa aacatcagtc agcagaatct ctagcaaagt
    42601 ttatgttaaa caataaatcg ttcttaggta taacactgtc aatattagat gaatggaaaa
    42661 ataatattga tagtagtaaa attgaggata ttgtaaaaaa taattttaga tttgaggaat
    42721 ctataattaa agataagaac tataaagagt ttataaaatt attaaactca ttttataacg
    42781 gaacagaaga tgagttaaac ggtagaagag gaagattttt agagttgatt tgggatgttg
    42841 taggaacata taacggaaaa gaatttacac aaaaaataga tgaggccata gtgttagaaa
    42901 atgaagtgaa aatatcagaa aaagatatag atattgtcta tataggcgaa attaaagata
    42961 aagggatagc aaattttatt gaaatgcacg aatgtaaagc atcagcaaac acaacactaa
    43021 gaactccatt aaaaccaaaa catagaggaa aactagaact gatgcaatca gtaattgaaa
    43081 tatcagaaac agaagaaatt aaatgtgatg gattaataat tacattcaat gctaacaaaa
    43141 gaaggcttga aagaaagcta aaaagctatg gatttgaata ctttaaaata attcctagag
    43201 cagaaataga ggaaagagtg tttaataagt aatttacact aatttataca aattaataga
    43261 tactaaaagt actctttttg taagagtgct atttttttga aattcattaa catataaact
    43321 atcaagaacc ttactcaaca caccttaaaa ttgatttaaa taactctttt tcatgcacaa
    43381 aattaatgat ataataaaaa agtaaatatg taaccccaac gcatatttac tgagtcaaac
    43441 attattatat agagcattct tcattatgga gagtgctttt ttcatttctt tgaataatca
    43501 tgttgattat ttataatatt ttcatttaat ttatctttat ctatcaaatt taatgcacaa
    43561 ttaatacaaa tgttagtttt catatgactt ttcttatgaa aagtaatata cttattatca
    43621 tctttgttta ttcctttatt acagtaatca cataatatag tcttagtcat atttttattc
    43681 ctttcatttt atattttcca taattaagtt taacatattt agtatatacc tatgtatata
    43741 tatttaaaac aatgtttttt attgcaatat agaatatatt gtataaataa aaaatatgaa
    43801 gaatagatat ttgataattg taaaattatg ttataattaa aatgcaagaa tatatcttgt
    43861 aagaaactac aatccaagag tggagcttca ttttctacat tccatccctt aaaaggaagg
    43921 aggtggagaa atgagcgaat ttttactagg agtgttagct agtttaacag ctagctttat
    43981 tacatatatt atttccagaa aagtaaaaag ccactctggc aggagtgact ttgagcttga
    44041 tgtaaaaatc aagtttaata aaaaacgaca ttaatattta gttaatgaaa cttcactcta
    44101 ggctaataga ttgtagtttc tttttttgtt tttgatacga atttacatct ttattatatc
    44161 gcattttgag aaaaaataaa actatgaata ttagaaatat attttatttt atctctaagt
    44221 atatatatta ttatccccct aaaaaacttt cataaaaaca aaaagaacaa tatctttttg
    44281 gcaactggct ggcataattt ataagaattt tataaatctt agtccctata gctttgcgtc
    44341 actaattttc tctagttttg ccgatttagt tttgttatac aactaaaata atacaataga
    44401 attagttaat gttcaacaag gttgtttgaa aattaaataa atttataggt atgaatagta
    44461 tttattccta aaaaggaaca gagtatttaa aggtcaaggt aagttagaat agtattgtga
    44521 actaacattt gattatgcga aattctatga aacaggaacc ctgtgacttt agtcatggga
    44581 ggttcagtgt atatcgcgta tttcaattgt tataagtatt ttatttattt ggactaacta
    44641 ataatagcca agtggatgtg gtaaaactac attacttaga ataatagcag gtcttgaaga
    44701 tgtaaatagt ggaactataa ttctccagga taaagatatt acaaatttag agccatcaaa
    44761 gagaggtttt ggtatagtat ttcaatcata tgcattattt ccgaatatga ctgcttataa
    44821 caatatagct tttccactaa aagagagaaa agtttcaaaa gaaaaaatag ataataaagt
    44881 taaggaagta cttgaaacag ttggattgac taatgaagct cataaatacc ctaaagcatt
    44941 atcaggtgga caacaacaga ggattgcaat agcaagagca ttagctcttg aaccaaagtt
    45001 tttactttta gatgaaccaa tgtctgcatt agatgcaaag gttagacaca agcttagaat
    45061 ggacattaaa agattacaaa aagaacttaa tataacgaca ataatggtaa cacatgacca
    45121 agaagaagct ataactatgg cagataaaat agctattcta aatggaggag atataatgca
    45181 aatagggact ccagaagaaa tataccaaaa tcctcaaaac ctatttacag ctcaatttat
    45241 aggagataca aactgttttg ataatggaga ttctatatta actgtaagac cagaatatgt
    45301 tcaaatagag aaatcgacaa aagaaaacta ccaagggata atatcaaata tagagtttag
    45361 agggaattta ttgagagttg aaataaaaga taaattaaat gaaaatttca taataagtga
    45421 tgtttctata aaagagtggg ttaatttaaa tttagtagaa ggtgaccttg taaaaataag
    45481 tatagacgaa aaatactatt taaagtatcc aaaagttaaa ggagcataag tgtatgaata
    45541 ataatgctat aagttctaaa agtataagtc ttaaatcaaa aatgaattta gatataaaaa
    45601 aatgtatgct tacagtatta gttatgtctt tagtaatatt tttattagca cctataatat
    45661 atctatttgt acaggctttt ttagataaag atggagtctt tgtaggatta caaaactttc
    45721 aagaatactt ggcttctgaa tctctattaa attctctaaa aaatacagta tttgtatcag
    45781 ttatatcaac tgtaatatca ctaacacttg cattagtata tgcatatgca ttaactagaa
    45841 caaagattaa atttaaaggt ttttttaaat cattagctat gtttcctatg tttgctccaa
    45901 caatgatgca tgcaataggt ctagtatatt tatttggaaa tcaaggtttg gtaactaatt
    45961 tacttggagt gcatgttcca atatatggag cagtgggaat aatattggca caaattatat
    46021 atgtatttcc tcaatcattt caaatacttt atatatctct aagttcaacc gattatagac
    46081 tatatgaagc tagtaatact atggggataa gcaagataag agaatttata agcataacaa
    46141 tcccaagtat aaaatactct ttaataagtt ctgcattcgt atcgtttaca ttatgtttta
    46201 cagattttgg agctccaaag gtgataggag gagagtttaa tgtattatca atagatgtat
    46261 ataagcaaat tatagggcaa cagaatatgc caatgggagc aactgtatca atattacttt
    46321 taatacctgc aataatatcg tttatagtaa ctaaaaaaat tgaaaaaaat caaaattcat
    46381 atataacttc aaagtcaatt ccatataagg ttaaaactaa taagttaaga gatagtattt
    46441 taggaggggt tgtaggaatt attgcatttg gtataatagc tgtaatgtta actgtaatct
    46501 tatcttcatt aatatcagtt tggtcatatg atttaagact gacactggaa catttttcta
    46561 tgaaaaacag tattgatggg attaaaccat ttataaattc aataaaaata tcactattga
    46621 cagctattct agggacgagc tttgttttct tatttgcata tttgaatgaa aaaacagaaa
    46681 aagctccata tttaaaatca tttgggtatt ttttaagtac attgcctatg gcattgccag
    46741 gattagtttt aggtatagct tatgtattat tttttaataa attagagttt aattttatgg
    46801 atacaatata cattaaaaat ttgtttaatg gattatatgg aacattactt ataatggtta
    46861 tatgtaatat agttcatttc ttttcagtag catttataac agctactact gctatcaaga
    46921 aagtagataa agaattggat atggtagcta aatcaatggg aataaacagc gcatcaattc
    46981 ttaagaacgt aactatacca ctttgtttgc cagcagtttt agagaacttt atgtactttt
    47041 tcctaaactc catggtgaca atatcagcat tagtttttat atatactgca agttcaaaag
    47101 tagctgcaat atcaattgta caactagatg ataaggggag tactgcacag gcagcagcac
    47161 tagctgtgtt aatattagtc acaaatatat tagtgaaagt aatatatgaa tttataaaga
    47221 atcgtttaga aaaaagaaca aactttaatt aaataattta tcttataaaa cacaaattta
    47281 aaaagtctat tcttatgatt tattatttaa agaatagact ttttaaattt attattgata
    47341 ttgtttatta attttccttt tgttatcata catttgagaa tctgcacgac gatatgtatc
    47401 aaataaagaa acatctactt tttcatcaaa aatagcatat ccaatagaca ttgataattt
    47461 taattcatta gttgagtttt ctt
//
LOCUS       DAEPUT010000023        46421 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.023, whole genome shotgun sequence.
ACCESSION   DAEPUT010000023 DAEPUT010000000
VERSION     DAEPUT010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46421
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.023"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            455..4003
                     /locus_tag="KRL22_001458"
     CDS             455..4003
                     /locus_tag="KRL22_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1271957.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADIALY
                     SAKGKGKNCYTLYDKKFDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            4188..6122
                     /locus_tag="KRL22_001459"
     CDS             4188..6122
                     /locus_tag="KRL22_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBH1271958.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            6228..7223
                     /locus_tag="KRL22_001460"
     CDS             6228..7223
                     /locus_tag="KRL22_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1271959.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            7195..7980
                     /locus_tag="KRL22_001461"
     CDS             7195..7980
                     /locus_tag="KRL22_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH1271960.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7968..8666
                     /locus_tag="KRL22_001462"
     CDS             7968..8666
                     /locus_tag="KRL22_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271961.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8789..9262
                     /gene="ybaK"
                     /locus_tag="KRL22_001463"
     CDS             8789..9262
                     /gene="ybaK"
                     /locus_tag="KRL22_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBH1271962.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9459..10298
                     /locus_tag="KRL22_001464"
     CDS             9459..10298
                     /locus_tag="KRL22_001464"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HBH1271963.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10311..10859
                     /locus_tag="KRL22_001465"
     CDS             10311..10859
                     /locus_tag="KRL22_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HBH1271964.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10925..12106
                     /locus_tag="KRL22_001466"
     CDS             10925..12106
                     /locus_tag="KRL22_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBH1271965.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12401..12787
                     /locus_tag="KRL22_001467"
     CDS             12401..12787
                     /locus_tag="KRL22_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1271966.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYNMDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            12937..13200
                     /locus_tag="KRL22_001468"
     CDS             12937..13200
                     /locus_tag="KRL22_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1271967.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13329..14171)
                     /locus_tag="KRL22_001469"
     CDS             complement(13329..14171)
                     /locus_tag="KRL22_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1271968.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14466..15200
                     /locus_tag="KRL22_001470"
     CDS             14466..15200
                     /locus_tag="KRL22_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1271969.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            15210..16343
                     /gene="nagA"
                     /locus_tag="KRL22_001471"
     CDS             15210..16343
                     /gene="nagA"
                     /locus_tag="KRL22_001471"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH1271970.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAKVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGEVVYKNI"
     gene            16442..17191
                     /gene="nagB"
                     /locus_tag="KRL22_001472"
     CDS             16442..17191
                     /gene="nagB"
                     /locus_tag="KRL22_001472"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBH1271971.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17366..17638
                     /locus_tag="KRL22_001473"
     CDS             17366..17638
                     /locus_tag="KRL22_001473"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271972.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            18298..19002
                     /locus_tag="KRL22_001474"
     CDS             18298..19002
                     /locus_tag="KRL22_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1271973.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            19004..20491
                     /locus_tag="KRL22_001475"
     CDS             19004..20491
                     /locus_tag="KRL22_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1271974.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIEFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            20696..22309
                     /locus_tag="KRL22_001476"
     CDS             20696..22309
                     /locus_tag="KRL22_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1271975.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(22671..23501)
                     /locus_tag="KRL22_001477"
     CDS             complement(22671..23501)
                     /locus_tag="KRL22_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1271976.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKTYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            23574..25301
                     /locus_tag="KRL22_001478"
     CDS             23574..25301
                     /locus_tag="KRL22_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271977.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            25338..27200
                     /locus_tag="KRL22_001479"
     CDS             25338..27200
                     /locus_tag="KRL22_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271978.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            27533..28222
                     /locus_tag="KRL22_001480"
     CDS             27533..28222
                     /locus_tag="KRL22_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HBH1271979.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTISVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            28327..29013
                     /locus_tag="KRL22_001481"
     CDS             28327..29013
                     /locus_tag="KRL22_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HBH1271980.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            29030..30937
                     /locus_tag="KRL22_001482"
     CDS             29030..30937
                     /locus_tag="KRL22_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HBH1271981.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSADLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRLLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMSPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            31390..32079
                     /locus_tag="KRL22_001483"
     CDS             31390..32079
                     /locus_tag="KRL22_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1271982.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            32515..33054
                     /locus_tag="KRL22_001484"
     CDS             32515..33054
                     /locus_tag="KRL22_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1271983.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            33073..34116
                     /locus_tag="KRL22_001485"
     CDS             33073..34116
                     /locus_tag="KRL22_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1271984.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            34118..34954
                     /locus_tag="KRL22_001486"
     CDS             34118..34954
                     /locus_tag="KRL22_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1271985.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            35059..35733
                     /locus_tag="KRL22_001487"
     CDS             35059..35733
                     /locus_tag="KRL22_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1271986.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIASGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            35733..36785
                     /locus_tag="KRL22_001488"
     CDS             35733..36785
                     /locus_tag="KRL22_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1271987.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            37015..37863
                     /locus_tag="KRL22_001489"
     CDS             37015..37863
                     /locus_tag="KRL22_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1271988.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            37853..39517
                     /locus_tag="KRL22_001490"
     CDS             37853..39517
                     /locus_tag="KRL22_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1271989.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASKITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGDGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLSIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     LTKSDTRFKSISNISKILIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            39566..40822
                     /locus_tag="KRL22_001491"
     CDS             39566..40822
                     /locus_tag="KRL22_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1271990.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            40845..42926
                     /locus_tag="KRL22_001492"
     CDS             40845..42926
                     /locus_tag="KRL22_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBH1271991.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSINEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            42963..44048
                     /locus_tag="KRL22_001493"
     CDS             42963..44048
                     /locus_tag="KRL22_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH1271992.1"
                     /translation="MRKYMNKFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKVVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            44102..45226
                     /gene="wecB"
                     /locus_tag="KRL22_001494"
     CDS             44102..45226
                     /gene="wecB"
                     /locus_tag="KRL22_001494"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBH1271993.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            45304..46278
                     /locus_tag="KRL22_001495"
     CDS             45304..46278
                     /locus_tag="KRL22_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH1271994.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQSLENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT        18527 a         4689 c         8032 g        15173 t
ORIGIN      
        1 ttactagaat tattatctgg taacttaagt tttgagtatt aatctaaagt atatgttttt
       61 atatggttta aattttatgt atacaaaatt aatttgctaa ctgaatcata taaaaaaaac
      121 aaaatatttt ttagagggaa tgattagata gaattttttt gttatgaaat taattgaaga
      181 gtaattaatt agaaaaggaa tgaataataa tgaatatatt acattattac tttttgataa
      241 atcaaaaata aagttataat ttttaatatt aattaagaat gatgaaatat gaataaagat
      301 tttacaaata aatcttaagc tatcttattt aattctaata caggaagaag gtaaatgtat
      361 attgaaaaaa tcatagaaat agaagtaaac aatttaaata aatacaaagg tttgcaaaag
      421 aagtaatata attatataca atgaggatgt gagtatgatg aacagactaa agccaagaat
      481 tttaggtatt agtatcttgt ttattattat aattatttta acatgtggag ctgttttcaa
      541 gtttaaattt aaattagata ataaattaaa agaaaccaca catacatatt tgtctgagtt
      601 tacagaacac aatataatta atctcaagac aagacttagt ggtcaatttg acatgcttga
      661 atctattgct aacttcatag gaaacttgaa taatataaat gatgaaatgg tgattgattt
      721 aatggattct gatgtaaagc gaagttcttt aattagaatg actatctcta cattagatgg
      781 ggaatgttat tctaatgatg gaattaccca taatgttcaa gatagagatt attttaaaaa
      841 agctaaaaat ggagaaaaga atatatcaga gcctttaaaa tctattgtta ataataaaga
      901 aataatagtt ttatctaccc cagtttataa aagtgggaaa atagttggtg ttttaagtgg
      961 aatttatgat tcaaaaaagt taaatgagtt attaggatta tctgcatttg atgaaaaagc
     1021 agatgttttt gttgcaaaga aaaatggaga tatagttgct caaaaaacaa ataaaaatag
     1081 aaagacgcta tcatgtatat ttcagctttt tgacaaagat aattgtgatg aagatgattg
     1141 tctaaaaact ataaaagaaa atatgaaaaa tgataagtct ggatatttta attataactt
     1201 agataatgaa aaatttatgt taaactatca gccacttgga gttaatgatt ggtatgtttt
     1261 ttctgttgtg ccaaataaaa tagtatctat tcagtcagag aatatatctt atgatgtata
     1321 tatttttgca ttagaaatac tactagttat attgattttt ataatatata tagcatgtat
     1381 tataaataat aacaccaaaa ttattataaa tgaaaaagaa aaatttaaag tactcactga
     1441 taatatatta ggaggggtta aaacctgttt aaaagatgaa tatatgacta tgacatatgt
     1501 aagtcagggg tttttagagc ttacaggtta ctcttgtgaa gatttaaata aaatatttaa
     1561 aaatagattt aaagacatga tttataaaga tgatttagac aagtttaatt gtattattct
     1621 aaatcaatta gaaaaacaag ataaaattga agttgaatat agaattgtaa gaaaagatgg
     1681 aagtataatt tggattttgg agagaagtaa gtctataaat gataataaag gaagtgagtg
     1741 tattcaggga gttttaactg atataacaga acttaagaaa atacaagaag aattagattc
     1801 aaaaagattt gaaatacagg ctatcaatga tagtattgtt ggtggaatag tgataactga
     1861 gataaatgat gattttgata gtatatattt aaatgaaggt tatttaaata tgattggata
     1921 tacacgcaaa caactggaag atgagctaaa taataaatta atcaaactta tttttaaaga
     1981 tgatagaaca gaattaatta atagtataaa caaacaactc aaattaagtg atacatttgc
     2041 atctgaacaa agagttgaaa aaagggatgg cactattata tggattttat taaaaggaag
     2101 aaagatgatt tatgataatg gaaaatctgt actttgttgt gttattgtag atattacttc
     2161 tgctaaatta ttagagcaag aacttaaaaa gagtgaagaa cgtcatgaaa tcattctaaa
     2221 gcagacgcaa aatattataa tagaatggga tatagaaaaa gataaaatga atatatcacc
     2281 taattggtat aataagttta aatatgaccc tataactgaa aacgcaacaa aaaatataat
     2341 taaatcagta gatatatatc atgatgatat ggataagttt atttcattaa ttaaacttac
     2401 ttcacaaggt agtgagtatg aagagtgtga aattagactt agaactagag atactattta
     2461 cgcttggttt agtataaagg caacaacttt atttgataat aatggtaaac cttataaagt
     2521 agtaggaagt ttgactgata ttgatgaatc aaaacgagaa gctgaaaagt tgaaagaaag
     2581 ggcagaaaaa gaccctctta cagatctgta taataaaaaa gcatcacaat cacttataga
     2641 ggagtacata acattggata aaaaaagaaa aggtgcttta atgattattg atattgatga
     2701 ctttaaagga ataaatgata atttaggaca tttatatggg gatgctgtat taagtgaaat
     2761 tgcaaatgac ctaataaatc tatttagagc aaccgatata gtaggcagaa ttggtggaga
     2821 tgagtttatt gtatttataa aagatatttc tgaaacaaga gatattataa ataaagcaga
     2881 agaattggta aaaacatttg aaaggtcttt tttaggtaaa ggacgaaatt ataaaatatc
     2941 attaagtgta ggaattgcta agtttccaca agatggtatg gactatatga cactatttag
     3001 aaatgcggat atagctcttt actcagccaa agggaagggc aagaattgtt atacattgta
     3061 tgataaaaaa tttgataaag tccaatatat aactaataca agaaatgcag gagatagtga
     3121 taatgtagag atgtctttta aagaacatat cacaaattat atatttgata tactatatga
     3181 atcaagtgat atagaagtgg cagtaaattt aattctaagt attgtaggta aacactttaa
     3241 tgtgagtcgc atgtatatat ttgaaaattc agatgataat cgagtatgta aaaatacatt
     3301 tgaatggtgt aacgaaggtg taacctcgga aattaataat cttaaaaata tttgttacaa
     3361 ggatttaggc aactatcttt taaattttaa tgcagatggg ttattttatt gtaatgatat
     3421 tgaaaattta ggtagtgatg tgaaaaaagt acttaagcca caaggcatac gttcaatatt
     3481 acaatgtaaa attttagagg gtaatgaatt tagagggttc ataggatttg atgaatgttc
     3541 atataatcgt atgtggacta atgatgaagt gaacactttg acatttatat ctaaaacgct
     3601 cagtatgttt ttattaaaaa tgcgtattca gagtaagcta gaagagtctt taacaattca
     3661 aaaatctgtg atggataata tggatatatg ggcatatgtt gttgacagga atacctatga
     3721 attactattt atcaataaaa aaatgcttga gtcagcacca aacactcatg taggtgattt
     3781 atgttataaa gcgatatgga ataatcaaga taaaccttgt aaaaaatgcc ctatgatata
     3841 tttaaaagat ggtgatgata cttataaatc attcatgcat aataaaaagt ttgaggtaca
     3901 ggcaaatata actacaacta ctttgaaatg gtttgatggt aaagatgcat gtttaatatt
     3961 tggaagtgaa ataactagta ttgaagctga agaaaatact taaaatactg tgttatatat
     4021 atacttaaaa tcgcaatttg aatttattag acttaaaatg tctatataaa tcatttaagt
     4081 tgtggtttta agtatttttt atgatataat taagcgttaa gaacaaaatt aaaagatact
     4141 tttgtataaa aaaatatttg ttaaatatat attgagcagg tgataatatg gaaaataagt
     4201 ttttaccaat aagcaaacaa gatatgatag atagaggatg ggaagaatta gattttgttc
     4261 tagttacagg agatgcttat gtggaccatc atagttttgg aacagcaata atatctagag
     4321 ttttagaaag tgctgggtat aaagttggaa taatagctca accagactgg agaactacag
     4381 atgattttat gaagctagga aaacctagac ttgcatttct agttaatgca ggaaatatgg
     4441 attcaatggt caatcattat tctgtaagta aaaagcatag agaaaaggat atgtattctc
     4501 caggtgggaa aatgggttat agaccagata gagctactat agtatattgc aataaaataa
     4561 gagaagcata cagtgatgtt gcaatagtaa taggtggaat tgaagcgagc ttaagaagat
     4621 ttgcacacta tgattattgg agtgataagg ttagaaagtc tatgttaata gatagtggag
     4681 cagatttatt agtttatggt atgagtgaaa agcagattgt agaagtagcc aatgcactta
     4741 atgatggata tgacccaaaa tacattagac atattgatgg gacatgctat atttcagata
     4801 cattggaaga aatatatgat aaatatatat taattccatc atataaagaa atttgtgaag
     4861 ataaaatgaa gtatgtagaa gcttttaaaa ttcaatatga tgagcaagac ccatttagag
     4921 gtaatataat tgttcaacct catggaagta agtatctggt tcaaaataag ccagaaaaac
     4981 cacttagtag agaagaacta gatgaagtat atggattacc atatcagaag acataccatc
     5041 ctgtgtatga aaaatttgga ggaataccag ctatagaaga agtaaaattt agtatagtaa
     5101 gttcaagagg ctgttttggt agttgttcat tttgtgcaat aacatttcat caaggtagag
     5161 cagtgcaaag tagaagtgaa aaatcaatta ttgatgaagc aataggaata acaaatttag
     5221 atgattttaa agggtatata catgatgttg gaggtccaac agctaatttt agaagaccag
     5281 catgtaaaaa acaaattact aaaggtgctt gtaaaaatag acaatgctta tctccatcac
     5341 catgtaaaaa tttagatgca gaccacagtg aatacttaca tttacttaga gctgtaagaa
     5401 aattacctaa aataaaaaag gtgtttgtgc gttctggaat tagatacgat tatgtaatgg
     5461 cagataagaa caataaattt cttagagagt tgatagagca tcatgtaagt ggtcagttaa
     5521 aggtagcccc agaacatata tcagaagaag ttttaaagta tatgcaaaaa ccagcaggaa
     5581 aaacttatga taaatttaga cagaagtttt ttgctataaa tgaagaatta ggtaaaaagc
     5641 aatatttgat accctattta atgtctagtc accctggttc taccttaaat agcgctatag
     5701 agttagcaga gtatttaaga gatactcact accaaccaga gcaggttcag gatttttatc
     5761 caactccagg gactctatct acaaccatgt tttatacagg tattgacccg cttacaatga
     5821 agccagttta tgttcctaaa tcaaaacgtg acaaggcgat gcaaagggct ttattacaat
     5881 atagagcacc tagaaattat gatttggtat actctgcgtt agttgaagca ggaagagaag
     5941 acttaattgg ttttggacat agatgtctta taaagccaaa aaatgaaaag ccttatttta
     6001 atagaaataa ttctaaaaaa aatgtatcta aaggaacaaa taaaaacaaa aaaactaata
     6061 caaataacag aagtaataaa aatcaacaaa aaagttcaac taaaaaaaag aaaaaacatt
     6121 aaagtataaa taaaaatact taaaaaagaa ggattattcg ataaattaac agaaattagt
     6181 ataaataaat ataattattt taatgacgtt acctttggga ggaagagatg aaaaagtata
     6241 tttctataat attattagtg gtgttgacta tggttgtttt ggtaggatgt tcaccaggaa
     6301 aagataaccc taaaaataag gagctatcag ttgtcaaaca agtaaaagta gctgttccag
     6361 atggactacc agcagtggca atagctaaac ttgcaaatga aaatccagag attaaagaag
     6421 gatatgaaac agtgtatagc attgaaaaga cacctgaagc gatttccact agagtgatga
     6481 aaaaagatgc agatatagct atagttcctt caaacatggc tgcaatagcg tataataaaa
     6541 cttcatcata taatattgtt ggaactgtag gaatgggttc actttatttg gtgtcaacag
     6601 aaaatataaa agattattct gatttagttg gtaaagaagt tggatgtact ggaaaaggac
     6661 ttactccaga cataactata aaaagtcttt tgttacaaaa ggatataaat tattcagata
     6721 taaaatttaa ttatgtaaat tcagcaagtg aactggtacc attattggct actggtaaag
     6781 ttaaaacagg tattgttcca gaacctgcac ttagtgcttt gatgtctaaa aatccagaca
     6841 taaaaattat aaaaagttta aatgactcat ggaaggaagt aagtggttca aaagatggtt
     6901 atcctcaatc tactttaatt gtaaagtctg aatttttaag agataataaa gattttgttg
     6961 attcttttgt aggtcaatta tcaaatagta tagattgggc aaacaaaaat cctgaagaat
     7021 taggtgcata ttctgaaaaa ataaaaatat ctactgaatc aaagataata ggaaaatctc
     7081 ttgaaagagc taatttaaaa tatattccag ttaaggacat gattaaagat tataaaaatt
     7141 actatgagaa attagctaat tttgatgata agacattagg aggcaaagta ccagatgaag
     7201 caatatactt tgttgagaaa taaaaaaaat aaagaacaat ttatagataa aatggaggta
     7261 acactttctt gtgttatcct cttattttta tggcaaatta ttgctttaaa aattgataat
     7321 gatatttttt taccaacagt aggtcaagta tttaatagta taaaagagat tatgctaaat
     7381 tctagtttct atatagatat actttactct atggggagat gtttttttag ttttttactg
     7441 gctatgattt ttgctattat actttcaata gtgtcttatt taaatagatt ttttagaaac
     7501 ttattaaagc caatcaatgc tttgacacgt tcaataccaa ctatgatatt ggtagtactt
     7561 gcacttattt ggtttgaaaa ggatagtacc ccttttatag ttggatttac tatagttttt
     7621 cctatattgt atgataacgt tttgggcgct atattgaata tagacaagaa cttattagaa
     7681 atggctaatg tgtataaaat aaggtttata gataaggtgt taaaaattta tttaccagcc
     7741 ataaaatttc aaattatatc tatactagta tcaacattct ctttaagttt gaaagttgct
     7801 atagcaggag aggtatatag tcaacctaca tatggtattg gaactatgat acagactgaa
     7861 aaaattaact ttaacacatc tggaatattt gcatggataa ttattgttct tttaatatct
     7921 gctattttac aaatagctca aaagttttta gcaaggagag cttttttatg gaaaagataa
     7981 agttgagtat tgaaaatata aataaaagat atgatagtcg tattatattt agagatttta
     8041 atattgattt ttatgtaaat gaggtaaatt gtatccttgg aaaatctggt tgtggaaaaa
     8101 ctacactctt gaacataata agtgggatta ttaaaaatga caccaacaat ctaaatatca
     8161 aagaaaattt aaatagagta ggaaataagc ttgaagctag ttacatattt caagatgata
     8221 gacttataga ctggttaaca gtagaagaaa atataaagat agttgtaaat aaatactata
     8281 ataaaactca attaaataaa atttgtgatg aatacttgga attggttgga attagtgatt
     8341 ataaaaaatt ctatcctcag atgcttagtg gaggtattag acaaagagta aatattgcta
     8401 gagcttttat atatccatca aaaaatatta taatggatga accttttaaa tctattgatg
     8461 caaagaatac acagcttata atggataatt tcagaaatat attaagaaaa gaaaaaagaa
     8521 ctgtgttatt tgtaactcat aatattgagg aagcattgtt tttagcagat aggatattta
     8581 ttttaggaga ctctccaatt agaataaaaa aaatattaaa aaattctaag gaattggaaa
     8641 aaaatgaagt tttgaagttg atatagagtt ataataatac tgtcgtttta aaatatattt
     8701 ggttaaaatc tataagacta tattaaaata gtacagaata ttcaaaactg tgtataatgt
     8761 tcgtatttta taaaaaggaa gtgaatgtat ggttaagact aatgctatga gaatattaga
     8821 ttcaaataag attgattata aagtaatgtc ttatgaagtg aaaagtgaac atgtggatgg
     8881 tgttgaggtg gcacatgata taggaagaga tgtaaatgaa gtgtataaga cattagtaac
     8941 tcaaggagtt agtaagaata tatatgtata tgtaatacca gtacatgaaa acttagactt
     9001 aaaaaaggct gcaaaagtag ctaaagagaa aagtgtagag atgattcatg taaaagatat
     9061 aaataagctt acaggttata ttagaggcgg atgttctcct ataggtatga aaaagcttta
     9121 taaaactttt gtaaatgaaa gtgcaaagaa tttagataca attattgtga gtgcaggaaa
     9181 aataggatat caaatagaac tatctccatt tgatttacaa agacttataa aagtagaatt
     9241 tgtagatgta ataaaaaaat aagaattaca tataaaatat agagcttata ttcttaataa
     9301 taggtgttgt agtattaata aaatgaataa taattttaaa ataaatattc agttacttat
     9361 gtgtaattgg tataaaaata ttgagaaatt ttaaaaacaa tggtaaagtg taagtataat
     9421 cacgaatatt ttttataaag taatggaggg atgttcgctt gagaaaaata aaatctgaac
     9481 aaatcgtcga gcaggtaaaa aaactttgta tagaagcgag cctatattta ggagaagatg
     9541 ttttaagctg tataaaagaa aaagcgaaaa gtgaaaagag tgaagttgga aaaaatatat
     9601 tgaatatatt agttgaaaat gctgaaatag ctaaagaaaa aaatatacca atatgccaag
     9661 atactggtat ggctgtattt tttgttgaaa taggacaaga agttttaatt gaaggagaca
     9721 cacttactga tgctataaat gagggagtaa gacaagggta tgaagaaggc tacttaagaa
     9781 aatctgttgt aagtccaatt aacagagtaa atacaaaaga taatacacct gctgttattc
     9841 attatgatat ggtaaaaggt gataaaatta aaatagaatt tgcagctaag ggatttggaa
     9901 gcgaaaatat gagtaagatg aaaatgttaa agccatcaga tggattggaa ggaattaaaa
     9961 aattcataat agatacagtt tcagaagctg gacctaaccc atgccctcct atggtaattg
    10021 gagttggtat aggtgggact gtggacaaat gtgctcaaat agctaaaaag gcacttttta
    10081 gagaactagg tgaatttaat aaggacgaaa atatagcaaa acttgaaagt gaactattaa
    10141 cagctattaa taaacttggt ataggacctc aaggcttagg tggtactaca acagctttgg
    10201 gattaaacat agagactttt cctacacaca tagcaggttt acctgttgtt gtaaatataa
    10261 actgccatgc atcaagacat aagaaggtag taatttagga ggaaaataaa atgataaaaa
    10321 taactacacc tgtaaatgaa attgatatag caaaattaaa ttgtggagat acaattagtt
    10381 tgagtggtat actttataca gcaagagatg ctgctcataa aagattgata gattgtataa
    10441 ataaaggtga agaattacca tttgacgtat atggtcaagg aatatattat gtaggaccta
    10501 ctcctacaaa gccaggagaa gttataggtg ctgcaggtcc aacgacgagt tatagaatgg
    10561 atgatttgac tatacctctt ttagaaagag gtcttagatt gatgataggc aagggaaaaa
    10621 gaagtgatga agttatagaa ggtatgcaaa aatacggagc agtttatctt gctgcaatag
    10681 gaggagctgg agcatatatt tcaaattcaa taaaatcatg tgaaattatt gcatatgaag
    10741 atttaggagc tgaagctata agaaagattg tagtagaaga ccttaagctt acagtagcaa
    10801 tagatagcta tggaaataat atatatgagc aaggtcgagc aatttatgaa tgtaaataat
    10861 gtttagaaat aaatatgaat atcaaaatta aaaatagttg tgtatatttt aaggaggaaa
    10921 attgatgtct aaggattatg caaaattggc attagaaatg catgaaatca acaaagggaa
    10981 agtaagtgta gaaagcaagg tagaagttaa aactaaggat gatttatcaa cagcatatac
    11041 accaggggtt gctgaacctt gtttaaaaat acatgaaaat caagatgatg tttatagata
    11101 cacttctaaa gggaatctag tagcagtagt tagtgatgga agtgctgtac ttggattagg
    11161 taacattggt gctgaagcat ctatacctgt tatggaaggt aaagctatat tatttaaaca
    11221 atttgcagat gtagacgctt ttccaatatg tttaaagact aatgatgtag atgagatagt
    11281 taaatctgta gagttgatgg agcctgtatt tggaggtata aatttggaag acatatcttc
    11341 tccaagatgt tttgagatag aagagagatt aaaaaaatct ttaagtatac ctgtttttca
    11401 tgatgaccaa catgggacag caataatagt tgcagcagcc ataataaact caataaagtt
    11461 aattgaaaat aaaaaaatag aagatttaga aatagttata aacggagcag gagctgctgg
    11521 tatagccata gcaaagatac tacttaatat gaatgttaaa aatataattt tatgtgatag
    11581 aagtggagca ttggaagcta gtatagaaaa tctaaactat gttcaaaaag aaatgttaaa
    11641 agtaacaaat ataagaaatg aaaaaggacc tttaaaagat attataaaag gaaaagatgt
    11701 atttattggt gtttcaggtc caggagctgt tacaaaggaa atggttgaaa gtatgtctga
    11761 gaagccaata atattggcaa tggcaaatcc tactccagag ataatgccag aagaagcaaa
    11821 attaggtgga gcatttataa tgggaacagg tcgttcagac ttccctaatc aagtcaataa
    11881 tgtactggct tttcctggaa tatttagagg tgcacttgat gttaaggcta aagagataaa
    11941 tgaagaaatg aagatagctg ctgcatatgc aattgctaat acaataagtg atgaagaaat
    12001 atgcccagag tatatattac cagatgtatt taataagaat gtagtaaaaa atgttgctaa
    12061 ggcagttaaa gaagcagcga taaaaaccaa agtaaataga atataaattt ttatatgttc
    12121 atatatcctt atcttatcgg gtatatgggc atttttatta taggtttata ctcatatatc
    12181 cttactttta tatacatatc tttatgatta aaggtgttag aaaatgtagt aaattttata
    12241 ctatcagact ctatctttat tactttagta gatacatggt ggtaaaggtt tatagaaaaa
    12301 aatataggaa ggcagatttt tattgttgcg tatatatgag aatgatataa tatgaatatt
    12361 ataaattaat aaatttaaat ttatggaggt acaagagatg atggaatata aagttaatga
    12421 ccaagaactt aatgcttcaa tgtttatccc atttgtcaac aggatatggc caggagatta
    12481 taatatggat aaaacacaga ctgcattatc aaaaactttg aatataactg cttatgatga
    12541 taaagtgctt gtaggatgtc tgcgagttct ttcagatggt tattattttg gaacaattac
    12601 agaattgctt gttcttccag agtatcagaa acaaggcatt ggtagtaagc ttttccagct
    12661 tgctaaagag aacaccccaa ctatgctata ttttggtgca cagccaggag tagaagagtt
    12721 ctatgaaaaa aatgggtgcc aaagaagtct gcaatcctac ataataaaaa agaaagatag
    12781 ttattaaagt tccagctttc aataatctta aaagtacaat attttagtgg aatcatttca
    12841 ttttttatta ctaatatgac ataaacatgt catattagca ttgatatact tttaatatgg
    12901 ttaagagcca aagaaaaata taaggagtga tttaaaatgg aagaaactaa attttgccaa
    12961 tgctgtgcaa tgccaatggg acaaactgat gaattatatg ggacaaataa agatggaagt
    13021 aaaagtactg attattgtag ttattgtttt aaagatggtg agtttacagc tgatataagt
    13081 atggaagaga tgatagaagt ttgtatccct catatgcttc aaagtaataa ggatatgact
    13141 gaagatgaag caagaacaat gatgaacaat ttctttccaa cattaaaacg ctggaaataa
    13201 ttttatgcaa aattagttat atgcaaaaca tgaaatatgg tgttgagaat aaggggtggt
    13261 gtgctttata gcataccacc tgttttgtta cttggagttc agttattttc ctaaatattt
    13321 taaatatact attttagata agttccttct tcatcttgat aaattaatcc ttttttcata
    13381 agcactccaa gagctcgttt aaaatttttc ttacttgaat taaataatat agaaatatct
    13441 ttagggtcag atttatcatt aaatctcata tatccatcag aaccttctaa ataacttaaa
    13501 atcttatttt ctaaagtatc aagttcatcc tttctatttc ctctaggaga aagaccaagt
    13561 tttccatctt catatatttt tatgacatgt aaattttcaa gaacatcacc agtttttagt
    13621 tcagtaaagt actcattatg aagtattaca ccagcatatt tattgtctac acatatcatt
    13681 gcagaattat tagtttggaa tccatataca actccagtta caatatctcc tacattgtaa
    13741 gtatggtctg ttaataagta tgaatctata tctgtagtag cagcaattct tttgcttttg
    13801 tctaaatata tataaaataa atatttttcg tctctaaata gtggataagt cttagcttta
    13861 aaaggaacta atatgtcttt aggaagtccc atatctataa aagtaccaat gtctgtatta
    13921 tcaactactt ttaaatgtgc tacatcccca accttagcta aaggcggtat taaagttgca
    13981 gcagttctgt catcagaatc tttaaatatg aaagcattta cttcatcacc tatgtttatt
    14041 tcattttttc cgattaatct attatgaaga agtatatcgt cttttgtgtt attagtttgt
    14101 ccatccaaaa aatatccaaa ttcagttttt ctttttactg taagtttatt aaaatcacct
    14161 atgtttatca aattaaaatc atcctctcat tttatattta taatttagcc ataatatact
    14221 tatgtagtag tttgtcacag tatctatatt agtattagtg aaatttacaa taaataatat
    14281 agttatttat gtatttttca attctctagc ttcttatata gtataaactc caatttcttt
    14341 tttgtcttta ggttttatta aaatttttac aaaataagtt aaaaagtatt gaaataaaat
    14401 ttcttttaaa gtataattgg tatataccaa aattggtata taccatatcg aaaagtggtg
    14461 actatatgaa aatagtaaat aaatctagta atataccatt gcatactcaa ttaagttcaa
    14521 taataagaga gatgatagaa actggtgagc ttaaagaggg cgatgcaata atgccagaaa
    14581 gagaactttg caacatacaa aatgtaagtc gtatgacagt aaataaaacc attgttggat
    14641 tagttacaga aggacttctt tatagggtac aaggtaaagg gacattcgtt gcaaagcaaa
    14701 aaaagaagta tcagttttca aatgtaaaag gttttactga tgttatgaaa gaaaagggag
    14761 taaacataaa aacggatata ttatcctttg agatggaact accagatgat ttagttaaaa
    14821 gaaagcttgg aataagtgat aatactacaa atatatataa gattgtcaga cttagatata
    14881 ctgatggaga gccatttgga ttagaaatag tatatctatc agaagaaatg tgtaagggtc
    14941 taacaaaagg gatattggat aattcttcat tatatagggt tttaaatgaa aaatatggct
    15001 ataagataca aaaagctgaa caggtaatgg agccagtaat actttcagat gaagaaagta
    15061 agcttcttga aacagatgaa ggtgctttag ctcttaaact tcatagaaat tcctataata
    15121 gagaaggtag ccctatagaa tataccatat caatatttag aacagataaa tatcaatatg
    15181 aaatagtatt gagtgagtag gtgaataata tgaaatgttt aattaatgga aagataatat
    15241 taaaaaatca aatcttagaa aataaagtat tagtatttga tgaaaaaata attgatatag
    15301 ctgatagtgt accaaaagat tgtgaagtta tagatgctga tggaaaatat atatctccag
    15361 ggcttattga tattcatata catggaaaca tgggaaaaga tacaatggat tcgactgatg
    15421 aatctattga aacaatttca aaatcaatta tgagacatgg agtaacatct tttctgccaa
    15481 ctacaatgac tatggataaa gaacatgttt atgatgcact tgaagttatt aaaaaagccc
    15541 aaaatagaaa gcttgaaggg gcaaaggtat taggagcaca tttagaagga ccttttataa
    15601 atgagaatta taagggagca caaaatgaaa aatttataat aaattcaaaa tacgaattta
    15661 taaaagaata taaagatgtt ataaaagtta taacttatgc tccagaaaaa gatattgatt
    15721 ttgattttac tagagaaata aaaagatgta cagatatagt tttatctatt ggtcatagta
    15781 atgcaaatta tgaccaagct aaagaagcta taaatttagg agtaactaat gtaactcaca
    15841 tgttcaatgc aatgactggt ttaaaccata gagacccagg cgttgttggt gcagcactta
    15901 caactaatgt gtacagtgag ttaatagcag atacaatcca tataaataaa gatttatttc
    15961 aatttatact aaataataaa gggaaagaaa gactgatttt aataacagat tctatagaag
    16021 ctggtggtct tgaagatggc aattattctc ttggaggtca gaaagtcata gttaagggta
    16081 atgaagctag acttgaaaat ggagcattag ctggaagtgt gttgtcttta aataaaatgg
    16141 tatttaactt cttagataat acaaacctta aagtgaatga agcaattaat ttagcttctt
    16201 taaatccagc aacatctttg ggaataaatg acaaaaaagg aagcttagaa ataggtaagg
    16261 atgcagatat agctgtattt gatgagaatt tagattgtaa aatgacactt tgcttggggg
    16321 aagtagtata taaaaatata tagtatacaa aacaaacctt aaagacagta aaaacaatat
    16381 aaaaaataat aaattaaact tacattagta aaagtagtag ttaaaattta ggaggaataa
    16441 gatgagagta ttagtgtgta aagattatga tggaatgagt aaaaaagccg ctgaaatgat
    16501 agcagctcaa atagttttaa aaccaaattc aatactggga ctagctacag gaagtacacc
    16561 agtaggtatg tatagagatt tagtaaaaaa atacaatgat aatatagtag atttttcaga
    16621 tgtgatgagc tttaatttag atgaatatta taagttacca atatctaatg accaaagcta
    16681 tgattatttt atgaaagaga atctatttaa tcatgtaaac ataaagccag aaaatactca
    16741 tctaccaaat ggaatggctg atgatattga aaaagagtgt atgaactatg aagcttctat
    16801 agatgcagct ggtggtatag atgtacaagt acttggaata ggtcgtaatg ctcatatagg
    16861 ttttaatgaa cctgatacta aatttgcaaa aagaactcat gtagttgaac ttacagagtc
    16921 tacaatagaa gctaatgcaa gattctttaa atcaagagaa gatgttccta aaaaagctgt
    16981 aagtatggga ataggttcaa tattgaagtc taagaaaata ttgcttttag cttcaggaga
    17041 agaaaaagct gatgcagtat ataatactgt ttacggagat ataactccag aagttcctgg
    17101 ttctatactt caacttcata aagacactat agttatagta gatgaagcag cagcaagtaa
    17161 actgaatcca aaagattata aattagtata agaatagaat gtagtttaag taaaaaatag
    17221 ctatcattga gtaatcaaat ttatttaatg atagctattt ttatttaaat tttttacttc
    17281 tttttattta aattagttat tattgtttaa attacttgct tattactttt tacgaaaact
    17341 cgttatcaag aagtatccaa ataagatgtt aaaaattatt atgtttagtg ggattctatc
    17401 aagcataata aaattaccta taattgggat attaccaact ggaaacataa agaagaatac
    17461 aggcatcagt gatagtaaaa aagatggaaa acaaagaaga agtaatcttg gaatatcaat
    17521 ataccaacta ccatcctttt tgtattctct aatcaataat tcagttccta gtaataaacc
    17581 aataccacca gaggaaatta aattaataaa aatgtatctt ttaaagtctt gcatataacc
    17641 agtgtgaaat tgagtataga aatcataatt taatttaacg gctaaaaaat acataagcaa
    17701 tagaatgatt aaaaataaaa gatatctaag agcttttttc attttaaatt ctcccttcag
    17761 aaatacttta tttagtttta ttttgttgga atctgatttt atcatttagt ttaagaaatc
    17821 cataatatta gtgaagaatg aaataagtat tatatatgaa taaatatttt tagaattaag
    17881 gtgaattgta gtgcttaata taactataat attaattgtt tgaatattca ataaaaagtt
    17941 tgaaaaatat caattttgat ataaactgaa taaatacagt tgaatattaa attattattt
    18001 tatcaaaaat atgcaaagta ctacaccttc aaatatcacc taaagtaatt aaaaggcaat
    18061 taaggtgaag tagttcaagt atttctaaaa taagtttaat aaattctata ataatttatt
    18121 ttttgcctta aaattgcctt aaaatccaaa caattttaaa actaatgtac tataaaaagc
    18181 tggtataatt taaatatagt aaaaaataag atttatctta tctattggga tttaattatt
    18241 taatcaatat atttatacca tttaatttaa ataaaaagtc tattaaggag tgagcttatg
    18301 agtaagttaa tttatatagc agatgatgaa gataatataa gaaatttggt aaagacattc
    18361 ttaaaaaatg aaggtcatga tgttatggat tttaaaacgg gtgatgaact tttagaacaa
    18421 tttaatataa aggagtgtga cttagtaata ctagatataa tgatgcctgg ctcaagtggt
    18481 tttgaagtat gtacaaaact tcgtgagaaa agtacagtcc caataatcat gcttactgca
    18541 agagatacag atatagatta tattacaggg ataaccttag gtagtgatga ttattttaca
    18601 aaaccattta gcccaatgtc tttggttatg agagtaaaat ctatatttag aaggatagag
    18661 tttgaaaaga aacaaaatta tgataaatat agtaactcga tagatatgga attaaaattt
    18721 ggtgatgtaa taataaataa aaagaataaa atcgttacaa gtaaaaatgt aaatatagac
    18781 cttacaccaa atgaatataa cctattgact tatttatttg aaaatataga tagagcagtt
    18841 tccagagatg aattattaaa caaaatatgg ggatacgata tagaagttga gacaagggct
    18901 gctgatgata cagtgaagag attacgtaaa aaaattttaa atacaaatat tttaatagaa
    18961 actgtatggg ggtttggatt taggttgaag gagaaaagtt aagatgaaga atggaaatga
    19021 caagaataga attggaaaga ttaaatccaa atttaaatta aagttctcaa agaaaaatat
    19081 aagcataaaa actaggattt tgttgagtat actttgtttg ataattatag tatttatgat
    19141 aatattagta tcttttaatg tatttcttga tacatatata aaaacaactg cgaatgaaga
    19201 attgacaaag tctacagaaa tagtagaaca tatggatagt aattttagac ctattaagcc
    19261 accacaagat gatggaaagc ttcctcccaa agtattatct aattttatga gaaatgtaca
    19321 agataaagtt aggatggcag aaacacaatc agatgctgat gctatggtag ttgattctaa
    19381 gtataacctg atatttccaa caagagagga tgatttctta aaaaatgttg atgagatgga
    19441 gctgattagg gagtgtattc aaaatgaaaa attagattta aattcagatg aaaatacacg
    19501 gatatctacc agaaataagg attattatat ttcaactgta aaaattacta gtatatatgg
    19561 tgaacaagac aagtatctta tactttttat agacatatca aaaactctaa atctagcaca
    19621 aaagataaat attgtattaa tatctgtaat gtgttttgct ggaatattag caatatttac
    19681 agctgtgatt ttatctgaga aaattgctaa accgataaaa gagttgtgtg agtttgcaaa
    19741 aaaaatgggt caaggagatt tcaaaagaac ctactttgac ttttcagata aagaattagt
    19801 agagctctca actgttatga ataagagtgc tgagtatctg gataagtatg ataatgaaca
    19861 aaaaatattt tttcaaaatg catctcatga attaaggaca ccacttatgt ctattaaagg
    19921 ttatgcagaa gctataaaat ataatgttat agatagtaaa catgcaagtg atataattct
    19981 tgaagaaagt gataggttaa gtgatatggt tgaagattta ttatacattt ctaaaataga
    20041 taatataact aaagattttg aacttgtaga atgtgattta agagaagtac tttcaaattg
    20101 tggagctagg caaaatgtaa gagctataaa taaggggata gaatttattt atgaatttga
    20161 tgaagaaatg gttttatttg aatgtgatga aaaaaacatt tccaaagcat ttatgaatct
    20221 tatagaaaat gctttgagat acgctaagag tgaaataaaa atagtgtgta agtataatca
    20281 aaaaaatata gttgtgataa tagaagatga tggaattgga atcaagaaag aagatttacc
    20341 tcatgttttt gaaagattct ataagggagt aggaggaaat catggaattg gattatcaat
    20401 agttaaatct attgtaaata agcatggtgg gcgtatatac gtagaaaatg gcaaaaaagg
    20461 agctaaattt actatattat ttaaattgta aaaaaattag agaaaatata gagatgtttg
    20521 aagttgtttt ttatatatat ctgttgtata ctgttgaaaa aagaacaata ttaagctgac
    20581 atatattacg atagttgaca tttaaagtaa atgcttaaat atagatacga aaggaaaagt
    20641 aaaatctgaa gtgtatttag gtttaagtaa gcttcttatt ttataaaaaa tatgtatgaa
    20701 agaacagctg atttttaata ttacaaattt agtaacggtt gtatttgaag cttttgtcat
    20761 ccatatgttt ttatcagact ttttaggcca gaaagaaggg tatataaaag ttgtaagata
    20821 tgctaaactg ggttttataa tatgtttagg attctgtaat ttaataactt taaaccctaa
    20881 aatcacaatg cctttaattt tcatccttat tttttcaaca tcatttttat ataaaggaaa
    20941 tttaaagaca cgattgttta ctactgtttt attaagtata ttctttatac tgtcagaaat
    21001 tgtagttaca agtatttttg ttttatttgt aaaagaaggc tttgaaataa tgcttgaaaa
    21061 taatagtata agagtattgg cgacaatttt atctaaaatt gtctttttgt tgacttgtaa
    21121 aattatttgt ctatttaaaa aggatgtaca tttagatatg cccataaagt attggctccc
    21181 tttattttta atacctatat ttagtttatt tctgtctgtt tctatctttg atgtaagtaa
    21241 attttttagt cttgaaagtt taaaatttct aagcttaata tctagtgttg gtattttata
    21301 tattaatttt attgtctttt atttatttaa atttattata gataaaacta aactatctat
    21361 gaaatatgaa ctacttgaaa aagaaataat tcataaggaa gaattaagac ttagtaatga
    21421 gtgttataaa attattgttg aacagactga ttctgtcgtt ttcgaatgga atatcaaaga
    21481 aaataaatca tttgtatcgc aggcttggac tgaaaaattt ggatataaca atgcatgtaa
    21541 gaatattttt aaagaaatta aagataaaga cttagttcat tctgaagata aagctatatt
    21601 tgaaggtttt cttgaaagta ttaaaaaaaa gaatatgcac aatcaagcag tatatcgttt
    21661 aaaaaaatct aatggtgaat atatttggtg tagaacatca attacaagca tttataatga
    21721 tgaaaatgaa cttttaagag ttgtcggagt aattgtagat gtagatagtg atataaaaaa
    21781 atatgaagag ttaagaacta gagcagaaag tgactcattg accaatatat acaataaagg
    21841 tacatttgaa aaattagtgg aagaaactat agttatgaat acaggtgata aaaaagatgc
    21901 attattcatt attgatttgg atgattttaa agaaataaat gataattttg gtcatccatt
    21961 tggtgatttt gtactaaaaa catttgctga taagatacaa actagttttg gtagtaaaga
    22021 cttagtcgga agaattggtg gagatgaatt tgttgtatat atgcaagatt atgttacaga
    22081 agtaaatttg cataaaaaag ctaaagaatt aaatagagta ctttcggata attacactga
    22141 tttgagtttt agttttgatg cttctgtcag tataggtatt gcaaggtatc ctcaagatgg
    22201 aacttcattt tttgaattgt ttaaaaatgc agatagagca ctttatagca taaaagcatc
    22261 aggtaaaaat tcatattgtt tatttgaaga agaactatat gtacagtgaa tttgaattta
    22321 gattttatgt gagagtaaga tttatatata cttgtggctg tctgatttat aaaatatgtt
    22381 actttgtata tttttatatg tttcagtaag gttaattaac ataagcaaag gtgtaagtaa
    22441 atttatatta gtttaagttt acttacacct ttataaaaat acaaataata gattcattta
    22501 cattcttaaa tgattaaagc tctttacctt ctaaacatgc ataacatatc gttataattc
    22561 cagtaaataa gactaaaatg ccattcctaa gattacagtt tcatcatcta ttactccaaa
    22621 tgtttttaaa gtaacttatt tcgctttgta tcataataat ttatctcctt ttacatttta
    22681 acttctgctg agatttgagt tagatattcg ttagaatctc gcacacttat atcatataga
    22741 agatattctt cataaacaaa atccccaata cgtaaattat tctgattaaa aaaatttaat
    22801 aacttttcat aagtcttgta aatagtttca taactccctt tatgataagc agttacataa
    22861 agtccctttg gtttgattga tacaggatat ttcttgtact ctttattaac ttttgtaaat
    22921 aaatatgaat atgattcaaa gtctttatta attatatctt cacctttaat gattgagcca
    22981 atcgtaccat aatcactcaa ttcatagttg tccataaagt taatacattc atataaaaaa
    23041 ttttcttcct catctcctaa aaattgttct ttatatgtaa caggtgtttt gaccaagtac
    23101 tcttcttcat gttcttttaa agtaatagta ttcgcatcta tattacaggc atttttagtg
    23161 aatgaaatag tagattccat tagagcttga atattattta gtttttcaat ttcattttta
    23221 atatcaatgg ttttcttttc taaaagctca attagtaaat taggtgttct tttgtctata
    23281 taagctttaa tttcttttaa aggcattttt acttccctaa gtgaagaaat tataccaaaa
    23341 atgctaagtt gatggtatga gtagtatcta tatccatttt ctttctttaa ttctggtgag
    23401 aaaagaccta tatcatcata atggaaaagt gtttttttat tgattccaca aatctttgca
    23461 aattctccag ttgtaaaata attttttgaa acttgactca taattataat tcctccttga
    23521 ctatcctgtt acagtatagt ttatcatagt attttgtaaa ggagtgtgat tatatgaaaa
    23581 aattaattca ttttttaaaa ccatatagag ttttaattgt tgtagttttg atatttacgt
    23641 ttttacaaac acttggaact ttgtatatac caacacttac agcaaatata gtaaataatg
    23701 gtgtagtaaa gggagatata gattatattg taaaaacagg tttaatgatg atgatagtag
    23761 ctggtataac agctttatca gctgtgttag tttgtaaagt atcagcaaat ctttcatctg
    23821 gattttgtag agatattaga gaagcagtat ttataaaatc acaagattta tcaataaatg
    23881 attttaataa tataggtaca gcatcaatga ttactaggag tactagtgat attactttaa
    23941 taggtcagtc tgtgtttatg tttattcaat tggtattacc agcaccaatt ataactgttt
    24001 ctggtctatt cttagcatat tctatagata aagcaatgac aattattatt gttgtagtaa
    24061 tgtttttatt catgctttca gcatttttag ttggtaaaaa gcttataaag ttgtttaaaa
    24121 tgatgcaaat aaagatggac aatatgaata gggtgttacg tgaggtagta actggagtaa
    24181 gagttataag agcttttaat aggagtcgtt ttgaaaaaaa gagatttgat agaactgcaa
    24241 tagattattc tgaaacagca atttcaataa ataaaatatt tgcagtactt atgcctattg
    24301 taatgttaat aatgaattta ggtatagtaa gtattatttg gtttggtggg atgagggtca
    24361 gtaatggaaa tatggaaata ggtcatataa tggcacttgt tgaatattgt atcttaattt
    24421 tattctattt aatcatggga gtaatggtat ttatgtacat acctagagca ggtgcatgtg
    24481 cagatagagt aaatcagata ttagatatag aacctgaaat tgtagatgga aatggtcata
    24541 aagatactgt ctcagagaga ggacatttag tatttaaaaa tgtaaccttt tcatatgcac
    24601 aatcagaaga acctgtgtta aataatataa catttgaagc aaaatctgga gaagtaactg
    24661 caattatagg aagcactggc tcaggcaaat ctactattgc aaatataata ccacgttttt
    24721 ttgaaattca atctggagaa atatctataa atggtcagga tattaagaag attcctcaaa
    24781 aagaacttag agataagatt ggatttgtac cacaaaaagc ttttttattt agtggaacaa
    24841 tagaagaaaa tataaggtat ggaaaagaag atgcaagtat tgaagaagta aagcatgctg
    24901 caagtatagc tcaagctgat gaatttattt ctgatatgga agacaagtat gactcatttg
    24961 tagcacaagg tggaaataat ttgtcaggtg gtcaaaaaca gagaatatcc attgcaagag
    25021 cgttagttag aaagcctgaa gtatatgtct ttgatgatag tttttctgca ttagatttta
    25081 aaacagataa aagacttaga aaagcgttga aaaatgaaat caaagattca tcagctataa
    25141 ttatagcaca acgtataagt acaatcatgg atgctaatca gattatagtt ttaaatgatg
    25201 gaaaaattgt aggtattgga aaacataaag atttacttga aaattgtgaa gtttataagc
    25261 aaattgcgga ttcacaactt agtaaagaag aacttgcata aaatgaagaa ttaatctgat
    25321 atttggaggt gtatgatatg agtgaaaaaa gaatagatga acaagatata gaagtactta
    25381 gttttgaaga tggcatgtca gcagaaaaag ctaaggatgc aaaaaaaact actaagagat
    25441 tattaaaata tatggcaaaa caaaagttta aaatattaat tatttttatt tcagtattga
    25501 taagttcagc gcttacagtt ttagcaccta tggttatggg aaaagctatt gaccaactat
    25561 ttaatggaat aaaaactgca gtccaaacag gtacaaaatt cagtgtgaat tttagtacta
    25621 tgggagggat agtatcaata cttctagggt tgtacttaat tagtgcagta tttatatata
    25681 ttcaacagta tattatgtca ggagttgcac aaaatctagt tcttagcatg agaaaagatt
    25741 taagtgataa actcaataaa cttcctctta agtactatga ttctcataaa aagggggaaa
    25801 cacttagtat agtaacaaat gatttagaaa aagtagcaga tagtttacaa gaaggattaa
    25861 tgcaacttat tacagcagta gttacagtag ttggttctat tgtaatgatg ataagtataa
    25921 gtgtaccact tacaatagta tcagctataa cattacttgt ttcattgggt attactgttg
    25981 taattgcaag aaaatcacaa gaaagattct ctgaaaatca aaaggcacta ggagagttaa
    26041 atagcaatat agaagagata tttactggtc aaatagtggt taaagcattt agtaaagaaa
    26101 aggatactat aagaaacttt aaaatattaa atcaaaatct ttataatgca agtagaaaag
    26161 cacagttttc gtcatatgca atatctccaa ttattagatt tataaaccta attggctatg
    26221 ttattatagc agttgtaggt gggatatttg catcaactgg agcaatgact cttggtagta
    26281 tacaagcgtt tattcaatat gtaaatcaag catcagagcc tactacagaa atatcttata
    26341 ttgtaaatat gcttcaagca gcaatagcat ctgcagagag agtttttaca gttatggacg
    26401 aggtggaaga gataaaggat gaagaatctt caaaggttat tagcatgcct aaaggtaaag
    26461 tacaatttga gcatgttaaa tttggatata gtgatgattt tattcttatg aaagatatta
    26521 atatcaatct aaatgcagga gataagattg caattgttgg acctacagga gctggaaaga
    26581 caactcttgt aaatttactt atgagatttt atgagataca aggtggaaga attactattg
    26641 atggtgttaa tataaaagat ttaaagcgtg gagaacttag aactatgttt ggtatggttc
    26701 ttcaagatac atggctgttt aatggaagta taaaagaaaa tattgcatat agtaagtcag
    26761 atgccacaat ggatgaaatt gtaagagcag caaaatcagc aagagtagac cattttataa
    26821 ggactttacc acaagggtat gacactatat tgactgagga tgcttctaat ctatctcaag
    26881 gtcaaaagca acttctaaca attgccaggg caatactttc agacccatca gtattgattc
    26941 ttgatgaagc aacatctagt gtagatacta gaacagaggt agaaattcaa aaggcaatga
    27001 ataacttgat gaagggaaga actagttttg ttattgcaca tagattatca actattcgag
    27061 atgctgattt aatattagta atgaaagaag gaactattat tgaacaagga agccataagg
    27121 aacttattga aaagaaagga ttctatgaag aactttataa cagtcaattt acaagtgaat
    27181 atgatgaaga tgttgtatga ttatcaagtt ttaggcaact aaatgattga taaatattaa
    27241 gttaaatata gtaacatgta aggttatatg gaataagagt atttctctat ttcatataac
    27301 cttttttatt tatcaaaata agataaaatt tcctttctaa attagattga agaatgtatt
    27361 tatcaatata aaagtaaaat aatcattatt attagtgaag taaatattgt ttgccacata
    27421 tatgccataa agatgcactt attttacgga gatttaacaa agtagtgtaa agtatactct
    27481 aaatataaaa taaatcaaat agagttaaat aaattgagag gtgatataaa tagtgaataa
    27541 aaaattgaac tatagatttg aaatgaagca caaaataact gaagcagatg tgttagcttt
    27601 aaaatcaaga ctctatccaa taatgaagaa agatgaaaat gcatctaaag atggaaaata
    27661 tcttattagg agtttatatt ttgatactcc tgaagataaa gcacttttgg ataaattaaa
    27721 tggcgttgca ataagagaaa agtttaggat aagattttat aataatgact gctcttatat
    27781 aaggttagag aaaaaaatca aacattacaa catgacatca aagctatcaa ctaatttaac
    27841 caaaaaagaa gtaataaata tactaaataa tgatattgaa tttctaaaag agtcgacaaa
    27901 ttgtttatta agagaatttt atttgaaatt aaaatgtgaa agattagagg caaaaagcat
    27961 agttgattac aatagagaag cttttattta tccagttgga aatgtaagag ttacaatcga
    28021 tagtgatatt aaaacttctg taaattcggt agatttattt aataaagatt tgccaactat
    28081 ttcggtaatt gatgagaata tgactgtatt ggaggttaaa tatgatgaat ttataccaga
    28141 ttttataaag gatttaattc aaattaataa gactacctct acagcagttt caaagtatgc
    28201 ttcaagtaga ttatatattt aagaataaag gctatgattt atataaagat atacataaat
    28261 aaggttaaaa aacaaataag ttaaaaataa ataaaataaa aaataaataa gttaaaaata
    28321 ggaaggatga ttttaattat gacatttaat gatattttta aatcaagttt tatagaaaac
    28381 gtatcaggtt tttcatttgt ggacagtgct ttagcactag gttcagcttt tttagtaggt
    28441 ttgtttatat atatggtcta taaaaagact tatatgggaa ttatgtattc tcgaccattc
    28501 aatgtgtcgc ttgtagcact tacaatgctt acaacttttg taatattggc ggttacttca
    28561 aatgtagttt tatccttagg tatggttggt gctttatcta tagtaagatt tagaacagca
    28621 attaaagacc caatggattt agtatttcta ttttggtcat taggttcagg tatagtttta
    28681 ggagcaggtt tgattccctt agctgtcatg ggttcaataa ttatgggatt gattctaata
    28741 ttcttttcaa ataaaacaat atctgaaact ccatatatat tgatggtaaa ttgtaataat
    28801 gaagattcag aagatatagc aactgataaa attaaaaaag tatttactaa atatcaaata
    28861 aaatcaaaaa gtgttacacc agaaaaagga atagaattag tgtttgaagt aagaatgaaa
    28921 gatggagaaa caagtcttat aaatgacttg agtcaagtag atggagttac taatgcagtt
    28981 cttgtaagtt ataatggtga ctatgtagca tagagaggag taatctttta tgaaagataa
    29041 aaaatttacc cttcttatct cgattatgat tatattttta tgtgctgtag ttggagttta
    29101 tagtacatct agcaacaaaa gtgctgattt atatagtgat gtatatattg aaaaatattt
    29161 taacagagac aaggttatgg aagttaatat agagatagat gaaagtgact tgaaggatat
    29221 gaatgaaaat gctataaaag aagaatttaa ggttgcaaaa gtaactgtag atggagatac
    29281 atatggaaac gtaggtataa gaactaaagg aaattcaagt cttatatctg tagcaaatag
    29341 tgatagtgat agatacagct ataagattaa ttttgataag tataatacta gtcaaagtat
    29401 ggaagggctt actcaattaa atcttaataa ctgttactct gacccatctt atatgagaga
    29461 gtttttaaca tatagtattt gcgaggaaat gggattagcg actccagaat ttgcatatgc
    29521 taaagtctct ataaatggcg aatatcatgg tttgtatttg gcagtagaag gattaaaaga
    29581 gtcttatctt gaaaataatt ttggtaatgt aactggagac ttatataagt cagatgaagg
    29641 aagctcgttg caatataaag gagatgaccc agaaagttac tcaaacttaa tcgttgaaag
    29701 tgataaaaag acagctgatt ggtctaaaat cacaaaacta ttaaaatctt tggatacagg
    29761 tgaagatatt gaaaaatatc ttgatgtaga ttctgtcctt aaaaatatag caataaatac
    29821 agctttatta aaccttgata gctatcaagg gagttttgcc cataactatt atttatatga
    29881 gcaagatgga gtattttcta tgttaccatg ggattttaat atgtcatttg gtggatttag
    29941 tggttttggt ggaggtagtc aatctatagc aattgatgaa cctacgacag gtaatttaga
    30001 agacagactt ctcatatcct cgttattaaa aaatgagaca tacaaaacaa aataccataa
    30061 atatctggaa gagatagtaa caaaatacct agattcagac tatttagaga atatgacaac
    30121 aaaattgcat gacatgatag catcatatgt aaaagaagac ccaacagcat tttatactta
    30181 tgaagaattt gaaaaaaata taacatcttc aattgaagat tctagtgata ataagggatt
    30241 tggtaataaa gggtttgaca acaataactc taataacagt gattctaata ataattctaa
    30301 tagtgaaaat aagcgctctg gaaatcaaag tgatgaaaaa gaagttaatg ctgaattaac
    30361 atcaagcgta gtcaaagcta atacagataa tgaaactaaa aataaaacta caaatgatag
    30421 tgaaagtaag aataatacag ataaagataa aagtggaaat gataataatc aaaagctaga
    30481 aggtcctatg ggtaaaggag gtaagtcaat accaggggtt ttggaagttg cagaagatat
    30541 gagtaaaact ataaaatctc aattaagtgg agaaacttct tcgacaaagc aaaactctgg
    30601 tgatgaaagt tcaagtggaa ttaaaggtag tgaaaagttt gatgaggata tgagtggtat
    30661 gccagaacca cctgagggaa tggatggtaa aatgtcacca ggaatgggta atatggataa
    30721 gggagatatg aatggtaaaa atggcaatat gaatatggat agaaatcaag ataatccaag
    30781 agaagctgga ggttttggca atagaggagg aggctctgtg agtaaaacaa caacatactt
    30841 caaattaatt ttaggtggag cttcaatgat aataatgtcg attatgttag ttggtgtatc
    30901 aagggtaaag agaagaagat ttataaagtc aaaataagat taaaattgaa tataaataat
    30961 tttaatactg ttaagtctaa atatttactt agcagtattt ttttagaaaa taatgtattt
    31021 ggttaataat ataaggtaat aaattgataa aaattaaata cagcatatta ataatacata
    31081 ataaagtaat aaaaaaactg tttaagtata ataacttata tttagacagt ttttttcatt
    31141 tataaataat ataaatgaaa ttgaaaacat ttgaaggata gaaattggtt ggataaatgt
    31201 ataaattact tcaccaaaaa ataatgacaa aaattgtaac taagttgtaa taaaatggta
    31261 gttatttagc ataaaataat gtatcataga agtatattat aaaattaata aaataagatt
    31321 tttgtaagaa aactgctggc ttttgatatt tagagtgagt agttaaatta tgtttaggag
    31381 gggtagaatt tgttgcaaaa agtattatgg aaatttttaa agctagtagt cggtttattt
    31441 atatgttcag ttggtatagt attgacgata aattgtaacc ttggattatc tccctgggat
    31501 gtatttcatc aaggactttc aaatcatata ggaataacta taggaactgc ttctataatt
    31561 gtaggctcta tagtagttat tgctgatgtc gttcttggag aaaatgtagg atggggaact
    31621 gtttttaaca tgctactaat tggattcttt atggatttac ttttatatag taatttaatt
    31681 ccagaggctg atagtttatt tgtaggaata attatgttga tattaggatt ggttcttttg
    31741 tctgttggaa tggtatttta tatgggaagt ggtttaggaa gtggacctag agatggtttg
    31801 atggttgcaa ttcaaaagaa aacaggaaaa tcacttaaat taataagagg tactatagaa
    31861 gttggagcat taatagtagg atttttatta ggtggaaaag ttggtatagg aactataata
    31921 agtgcatttg gattggggta tttcacacaa atggtatttg gcttatttaa attagattgt
    31981 agtaagatta aacatagatt tatagtagat gatataaaat ttatcaaagt gtatatgagt
    32041 ggtgagaaaa aagctgctgt tcaaaatata gttaagtaat ttaagaataa attcaacgaa
    32101 atgttaagta ttttaaatta acattttgtt tagatagata aattgaatat taaaagaata
    32161 ttaaaatatg aggattgcta gaacactata aaatatagat ttctagcaat tttttatttg
    32221 ttcaatattt ttttagtact agaagtctta ttctctattt aatgaatgaa ttaatttata
    32281 attagagata ctaaacttta tagatattaa tataaacacc tttaaactgt gtattttcca
    32341 aagcctttaa aatgcttgta tttattctaa ataaaaaaat aaaaaaatgt caaaaaaact
    32401 cttgtattat atccaaattt tatatataat tacctatgtt gtttagaaat tttaaactca
    32461 atgtttagta aacaaaatgt ttagtaaaat aaaacagaaa ctaggaggtg caacatggat
    32521 ataggtgaaa agataaaaag attaagaaca gaaaaacaac tgacccagga agagttagct
    32581 aatagatgtg aattgtcaaa gggatttatt tctcaattag aaaataactt aacatcacca
    32641 tccatagcta cccttataga tatacttgaa atactaggta caaatttaag ggaatttttt
    32701 aatgaaatag atgatgaaag aatcagtttt acaaaagaag atatgtttga aacagaagat
    32761 gaagatttaa aatataaatt aaagtggtta attccaaatt cacaaaaaaa tgaaatggag
    32821 ccaataataa taacattgta tccaggagga cagtataaag aagaaaagcc acatgaaggt
    32881 gaagaatttg gatatgtatt agcaggttca atatatgtcc atataggcga aaagaaaaat
    32941 aaagtaaaaa aaggagagag tttttacttt agaccgaaag caaatcacta tatatcaaac
    33001 gagggcaaaa ctacagcaaa agtgatttgg gtaagtacgc caccatcatt ttagaataga
    33061 ggtgtttaat aattggtaga aaatataata gaattaaggg atatatctaa acattatgaa
    33121 gaacttactg ttttagataa tttcaattta gatataaaga aaaatgagtt tctaacatta
    33181 cttggaccaa gtggatgtgg aaaaactaca acattaaaaa taatagcagg atttgagtat
    33241 gctgatgatg gtaaagtttt atttgaaggt aaggagataa ataatttgcc accatatgaa
    33301 agacaagtaa acacagtatt tcaaaaatat gctttatttc cacacatgga tgtttatgaa
    33361 aatgtagctt ttggattaaa aattaaaaag actccaaaag atgtaataga tgctaaagta
    33421 aaagaggttt tgaaacttgt tgcactagaa ggttttgaaa gacgacaagt tgaatcattg
    33481 agtggaggac aacaacaaag aattgcaata gcaagagctc tagttaatga accaaaggta
    33541 ttattactag atgaaccact tggagcactt gatttaaagt taagacaaga gatgcaaata
    33601 gaattaaaga gaatccaaaa aaaattagga ataacatttg tttttgtaac tcatgaccaa
    33661 gaagaggctc ttactatgtc agatactatt gttgtaatgt ataagggcaa aattcaacaa
    33721 atgggaacac cacaagatat atacaatgaa cctaaaaatt catttgtagc taagtttata
    33781 ggtgaaagta acatatttga tggaattatg atagaagatt ataaagttaa tttctgtaat
    33841 agagattttg agtgtgttga taaaggattc gaaaaaaacg aaaatataga agtagtaata
    33901 agaccagaag atataaaaat ggtaaagcca gaagaaggaa tgttaaaggg gaaagttaca
    33961 tctacagtgt ttaaaggagt gcattacgag atagaattga atgaaaatgg aagattgtgg
    34021 atacttcata atactaaaaa tgctgaggtt gggactgaac taggcatgga tatatatcca
    34081 gaagatatcc atataatgag aaaagagaat aactaagatg aaaagaaaat cttttttagc
    34141 atatccatat gtagtttgga gtgcgatatt tgtaataatt cctttaatat tagtagtatt
    34201 ttttagtttt acaaaagaat caggtggagg ttatgccttt acacttgaga attataaaga
    34261 agtaattgac cctatatata tgaaagtttt tgggcgttct attcttttag caggaggagc
    34321 tacattaata tgccttatag ttggttatcc agtggcatat ataatttcaa aggctcgtgt
    34381 aagtagaaga ggttcattaa tattattgtt tattcttcct atgtggatga actttctttt
    34441 aagaacatat gcatgggttg ctatattagg aaaaaatgga cttttaaata catttttagg
    34501 ttggtttgga atacaaccat tagcaatttt gtatactaat tttgccatac ttttaggtat
    34561 ggtgtataac tttttaccat ttatggttct tccaatatat acagcactat caaagatgga
    34621 taatgatttg ataaacgctg ctcatgactt gggtgcaaat aatatgacag tttttagaaa
    34681 aattatattt cctttgagtt tgccaggtgt aatgtctgga ataactatgg tatttatgcc
    34741 agcagtcact acttttgcaa tatcaagact gttaggtgga ggtaaaataa tgctggttgg
    34801 agatttgatt gaacaacagt ttacagttgt tggagattgg aactttggtt cagctatatc
    34861 gatatttatg atgatagtaa tattaatatc tatgtctata atgtcaaaat ttggagatga
    34921 atctgacaaa gaaggcggtg ggttactatt ttaaaattaa agaaaataac ttctaatata
    34981 tatttagcat tagtattctt atttttgtat gcacccatat ttgctttggt actattttct
    35041 ttcaatgatt caaaatcaat ggcaagatgg aatggattta catggaagtg gtatggtcaa
    35101 ttacttcaaa atgagagtat aatgagtgct ttatattata ctattgtaat agctatatta
    35161 gcgtctgtaa tatctacaat agtaggaact ataagtgcta taggaataca taagatgaga
    35221 ggtaagagta agaaattaat actaaatgta aactatcttc ctattttaaa tacagagata
    35281 gttacagcag tagctcttat gagtctgttt gtatttgtaa aaatggaatt tggatttaca
    35341 acaatgctat tggcacatat aatgttttgt ttgccatacg ttatactttc agttttgcca
    35401 aaaatgaagc aattacctga taatatagaa gatgcagcta tggacttggg agcaacacct
    35461 atatacgctc ttagaaaagt aattttacca caaataaaac caggtatagc ttctggattt
    35521 ttaattgcat ttactatgtc aatagatgac tttataataa gtttctttaa tgctggaaat
    35581 ggtgtaagca atctttctat agaaatctat ggaatggcta gaagaggtat aaaacctgaa
    35641 ataaatgcat tatcaacaat aatgtttgca gtggttctag gtttactttt actagctaat
    35701 aaaaaagaat ctatagtaag ggggattaaa taatgattaa gtttaaaaaa gcaatatccc
    35761 ttatagctgt aggtatgatg acagttactt tatttacagg atgtaataaa gcaactgatt
    35821 ctacaaaagt tttaaatgta tataatgttg gagattatat agatgagtct cttatagata
    35881 agtttgaaaa agaaacagga atagatgttc aatattcaac ttatgatact aatgaaatga
    35941 tgtatcaaaa agtaaagagt ggtagtacac actatgattt agtatttcct tcagactata
    36001 tggtagagaa aatgaaaaat gaaggtcttt tggaaaaatt agattttaag aatataccta
    36061 atatgaaata tttagataag agttttttaa atcctgtata cgacaaaact aatgaatata
    36121 gtgttgcata tatgtgggga actcttggaa tactgtacaa taagaaagaa gttaaagacc
    36181 ctatggatag ctggaatata ctttggaatc caaagtataa gggaaatata atgatgtttg
    36241 actctgttag agatactata gggataactc ttaaaaaatt aggatatagc atgaatagtg
    36301 taaatccaaa agaaataaat gaagctaaaa atcttttaat gaaacaaaag gatttagtat
    36361 tggcttatgt aaatgatgaa ggtaaggata gattgcttgg tggagaagtg gcaatgggta
    36421 tgctgtattc tggagatgca gttacactaa tggagcaaaa tcctgacctt gattatgcta
    36481 tacctaaaga gggaactaat aaatgggtag atgctatgtg tgtacctaca acagcacaaa
    36541 ataagaaaga agctgagctg tttataaact ttttattaga cccagagaat gcaaaagtaa
    36601 atgctgagta cattgggtat tcaacaccta atacaggagc actaaaatta ttagacccag
    36661 aaataactca gaatcctgtt gcatatccat ctaaagaagt acttgataaa tgtgaaactt
    36721 ttgaagatat tggtgaaaat ataaaattat atgacaaggc ttggatagag ttaaaatcaa
    36781 aatagggtct tgttgtttta agtaaattta cttaataaat acttaataaa actgttcttt
    36841 tttagaaaat ttattttcta attattgaac agttttattt tttgtttaag ttatattcat
    36901 atgcaattta aatagtttat taataaatga aaacttattt gtataatgac tttaataata
    36961 attagaaaaa atgggcaact taatagaata attggaggtg taaatttata aaaaatgaat
    37021 aggataaata aaaaaataga tttattaata ttggctttgc tcgtttttat atttttaatt
    37081 gttggaatag taatactatc gattaggaca gaaaataaat tgaatgtgtt cataatgtta
    37141 gcaataattt tttttataat aatgttaact tatttatcaa attcagtagt ggggttgata
    37201 acaagttcaa taattatatt tatgtataca tcctatattt tatataacaa tattactcac
    37261 aatatggatg ttgaatttat atcatatatg tggataatag caacaccagt atcttcaatt
    37321 ataatgggta atctgaacaa aagcataaat gaattgcaaa atacaaataa aaaactatct
    37381 gaacagtata aggaattagt gactattgat agtgaaactg gacttagaaa tttaaagatt
    37441 ttttataatg atgtaaatat ggagataagt aaatctatta gacataatac tgatttttct
    37501 cttatgatag taaaattacc atactacgga aacctacaga ctatatttgg tgaaaacaaa
    37561 actaataaaa tagtaaaata tattggttca aatattatag aatgtacaag aaatgaagat
    37621 ataatttata gtttacaaaa agatatgata gggatactaa tgccaaatac atctttggaa
    37681 ggttcaaaag ttgttaaaga cagaataaag aaaaggataa aagaattaaa cttagattta
    37741 aacaataggg gaaaatatgt aaatatagat gtcaaaattg catttttaca atataagagt
    37801 agttttggag atagtataaa ttttaagaat atagttgaag aggaacttca atatgatgtt
    37861 taaaatattt aataaaagtc tattaaaatt agtagttgta ttatcaatag tactgacaat
    37921 atcaaatttt agcttatctt catatgcatc aaaaattact tccagcacag ataaggtatt
    37981 aatcatatat gattctaaga aagaaacagc ttataataga gatattttaa atattatgag
    38041 gactctattg ggaagattta gttcagatat agagctatta aaattgagta actatgatgg
    38101 tgagataaat aaaaattatt acagtcatat atttatttta ggaatcaatg aaaactcata
    38161 taataatgat aaaaacacta aaaacttgat tagttcctta aattcatata aaggaactat
    38221 atgttggtta ggagatggta tagaaaatct tttggaacat aaaaaataca atttagacta
    38281 tgtaggaaaa acaaacaata tagttagtgt aaattataga ggtaaatcat ataacttgga
    38341 tgaacattat gtttttaaca ttgtagaatc aaaagataca agtaataaag taataggaag
    38401 tattaatgat accttaaata agtatccata tataataaat gataaaaatc ttttttatgt
    38461 atcaaaatta gatttagatg gagttttatt ttatatattt tgcgattcac ttaatgatat
    38521 ttttaatatt aagacgtttg ataaaggacg tatatttgta agaatagaag atgtacatgc
    38581 ttttagagaa ccaaaaaatc ttgtagagat agcggattat ttaagtagta agaatatacc
    38641 atttacgatt gcattaatac cagcatatgt aaatcctaaa aatcataaag taataacttt
    38701 atcagaaagc cctgaaattg tcaaagcaat aaaatatatg caagataaag gtggaactgt
    38761 gatattgcat ggatatactc atcaatacaa gaaagaagaa gtttctggag aagggtatga
    38821 attttgggat ggtaaaaaag atgaaccctt aaaagaaaat atgaagatat ttgtcaaaga
    38881 tagagttttg aatggtctta gagtatgtat agagaatgga atttatcctc ttgcatttga
    38941 agcgccacat tatgcaatgg aatcagaggg atataaagaa ttaaaaaaat atttttctac
    39001 ttatatgggg caacatcaaa ataatgataa aaaatttagc acaaatacat atccttatat
    39061 tattagggat acagaagagt ttaatatatt tatacccgaa aatttaggat atatagaccc
    39121 agaagataag tttacttttc aaaatataaa agaaaattta gataaactat ccattgtaag
    39181 aggttttagt ggagggttct tctttcattc atatttaagt atagagtatc taaaaaacac
    39241 aatagaatat ttagaaaaac agaatataga atttatgaat ttaagagatt ttaataattg
    39301 ggtaaaagtt gatgaaatac aaataagaaa taatggagat gaaattatag tcaactatga
    39361 taaggactta gatgaactaa ctaaaagtga tactagattt aaatccatat ccaatattag
    39421 taaaatttta atattcatag tatctataag tgttttaata tttgtgatta tatttatata
    39481 ttttaagaga atagataaaa agaaattttt aaaataaatg attttatatt agaatcaata
    39541 ttttaaaata ttttaggaga aatttatgag agatttaaat gtatcagagt atttgttcgt
    39601 atttagtctg tttagtatat ggtctttatt gcttataaat attattttag ctatgggtgg
    39661 atatatattt tattttaaaa actttgataa agaaataaaa gaaattgatg aatatcctat
    39721 gatatcaata cttgttcctg ctcataatga agctaaagtg ataggtagaa ctgtggagtc
    39781 tttgctatta cttaattatc ctaagagtaa gatggaactt attgttataa atgacaattc
    39841 ttctgataat agtaaagaaa ttttagaaaa tataaaggat aggtacaaca attataattt
    39901 cactataata aatacagata gtttaacagg tggaaaagga aagtctaatg cattaaatat
    39961 tggatatacg atttcaaaag gagattttat agctgtttat gatgcagata acacaccaga
    40021 taaaaatgca cttagatatc tagtacaaac tatagtaatg aatgatgaat taggtgctgt
    40081 tattgggaaa tttaggactc gaaataaaaa taaaaaccta ttaaccaaat ttataaacat
    40141 agaaacatta agctttcaat ggatgtcaca agctggtaga tggcaacttt ttaatctatg
    40201 tacaatacca ggaactaact ttatattgag gagaagtatc atagaagaaa ttggaggatg
    40261 ggatagtaaa gcaattgcag aagatacaga aataagtttt aggatatata aattgggata
    40321 caagataaag cttgtaccac aatctataac atgggaacaa gagccagaaa ctgttaaggt
    40381 gtggataaag caacgtacta gatgggcaaa agggaatata tatgtattaa tgaaatatat
    40441 aaaaaatata tttaaacagg gaagaaataa gattgtgttt gatatagctt actttttttc
    40501 tgtatatttt ctatttttaa catctgtaat tatatccgat attttatttg ttttaagtat
    40561 atctaaacta gtagaaattt ctattccaat taactttttt ctaatatgga tactatctta
    40621 tcttttattt attatagaag tgagtataag ccttactata gaaaaaggtg aagcaacaat
    40681 tgaaaatata ttcatagttg caataatgta ttttacatac tctcaactat ggctgtttgt
    40741 agctataaaa ggaatgatag agtatctaaa agatataatt tttaaaagag aggttaaatg
    40801 gtataaaaca gaaagatttt gattcatgta caggaggaat taacatgaaa aaatttatta
    40861 tatcaattat atctttagta ttgttttttt caaatatatc acttatatac aaagtaaatg
    40921 ctgatgagac taaagttaaa aattataagt ttgaaagaga tataactatt gatggtgtta
    40981 taggaagtaa tagtactttt tttgaagtaa ataaaaattg ggatattgaa gaagttttat
    41041 tgcatcttaa ttttagtaag agccaaatat taaatggaga tgtttcaagt ttaactgtat
    41101 tgataaataa tgtaccaata aaatctatta aattaaatgc taagacaaat tataaaaata
    41161 cattagaagt attagttcca aaagattata taattcaagg atataatgaa ataaaaataa
    41221 aaacatacaa aacaatatct gataaaattt gccaagatga ttccaatact gggaactgga
    41281 tggttattca caaagaatca tatatatcaa ttagatataa gcagaaaaag gtggaaaact
    41341 caataaatga atatccgtat ccatatgcag aaattgaaaa taatcataaa ttagatacaa
    41401 ctatagtagt accagataat atgactagag gagagactac agcagtgttt aatttggcat
    41461 cagcatttgg aaaaataaca aaaaatgatg atttaaagtt agatgttaaa ttatattcag
    41521 aaatgaaaaa ttggtcagat gataatatta tatatattgg taaacctgaa aatacagcag
    41581 aagaaatttt ggatatttta agtataaagg aacaaaccct attatcttca aactgtataa
    41641 tcaagcaagt agattcacca tacaataaga ataagaagat gatggtggta attggtagta
    41701 atgaagatga tttaataaag gcatcaaatt tattaataga aaatagactt tctaaccaag
    41761 ttttatcatc atcagtactt gtaaacaaag agactaatat aaaaattaat agggaacaaa
    41821 aattaaattt aggtcattta acattaaaag acttaggata ttctgacttt ttgttggaag
    41881 gagcatttaa tcaacaagct ttgtttgatg tcaaaatacc aacgggtaag gtattagatg
    41941 atggttcaaa gattatctta aatttaagat attctgacaa tttagatttt gaaaaatctt
    42001 tagttacagt gtctataaat gatgttattg tgggaagtaa aaaattggat aggtcacatt
    42061 ctaataatga taagttagaa ttaaaaatac ctaaagatat agataataaa aactattatc
    42121 aagttaaatt gacatttaat ttgagtataa aaaattcgaa ttgtgttact agagagagta
    42181 ataatccttg ggcatatgta tcaaataatt cttatttggc gttatctacg aaagaaaatg
    42241 aaaccttatc ttttgaaaat tatccgtatc catttgttag agatgatgaa tttaatgatt
    42301 taactgtgat aatgccagat tattcagggt cacaagctat gacctggatg tttagattag
    42361 gtgttacttt aggtgcgaat ataaattcac ataatggaaa tataaatgta attagaggaa
    42421 aagaatttag tgacaagtat aaggatacta atattgtagt ttttggagtg ccacataata
    42481 attctgttat aaagatgtta aataataatt taaatataaa gttcgataaa aattactcca
    42541 attttatatc aaatgataag ataagcttta ttgatgatta tggaaaaaat atttctacca
    42601 ttcaattaat aaaatcacca tataataatc aaaaaaatat catggtaatt agttcaataa
    42661 atgaaaaaaa cttatattta ggaatggatt atttgttgaa taaaagtaaa gttaatgatt
    42721 taaaaggaga tacattgata attgatgaat acggagaggt agaagattta gcttataatt
    42781 taaaatctaa gaaagaagta aaagattcaa gttggaatat gagtataaat aagacaacta
    42841 aagtattttt aatgatttct tttattacta taattgtagt catgatatta tcaatgctat
    42901 atataaaaaa atataaaaga agataatatg ataaatttat tattttaaaa gaggtatata
    42961 atttgaggaa atatatgaat aaatttaaat taaaaagaag tattttaatc tcattaataa
    43021 tcttaatttt tatatttata gtttactttg taagtattga gttaaaagat aggagtctag
    43081 taaataatca atataaaggt aagattaaat cagccaattt atctgtagat tatgaaataa
    43141 atcaagttat gaaggatata gataaattgg gattgaatac agtaaatgta cctataatta
    43201 taaatgtaga gtccattaat tctgatatta tgtcaataga taataatagt aaagaaaagg
    43261 caattaagtt aataaaaaaa ttaaataaaa aaggtatttc aacaatatta gaggcatatc
    43321 catggattga aaatggaaaa ttgtatgaga ctgactggaa ccctataaat aaaaaaagat
    43381 ttttttatac ttggcaaaat gccatattaa atgaacttat aattgatgta gcaaatccac
    43441 tggatgtaaa tgttttaaat attggttcta attttgtaca tttggaagaa tatcaacaaa
    43501 attggggtga aataatagat tttgtacaat ccaaatttga cggtcttgta acgtacagaa
    43561 ctaattggtg gtatacaaaa aaagatgatt taagtagtaa gttgttttat gaacaaaagt
    43621 tgaacaataa tttttttgat aagttagatt ttatatctat agcagcatat tttgagttaa
    43681 gcaataaacc tgttaataca gtggatgaat taatttctgc cttacactca tctactgtaa
    43741 acaatagagg acaaaatata aaacaagaaa tatataacct ttataaagct catagaaaac
    43801 ctatattttt tggagaatta ggtttttcaa atagagaaag tgcaagttct cagccgtgga
    43861 atcatactcc ttcaaaagtt gtaaatggcg aagaacaagc aaggtgtttt gaggcatata
    43921 agaaagtttt tgaaaatgaa gactggataa atggtttttc tgtgttttgt gtaggtaaaa
    43981 tagatgacga aaaaaatttt tacccatcaa aagagagtat aaaagttatt aagtcttggt
    44041 atgaataatt ttgaaagtgt agaatttata tagattaaat agatgattag gagagatata
    44101 aatgaatgac atcaaggtta tgactgtatt tggaactaga cctgaagcta tcaaagtagc
    44161 acctttaata aaggaacttg aaaaaagaga gaatataaaa agtattgttt gcgttacagc
    44221 tcaacataga gaaatgcttg accaagttat agaaaccttt aatataaatg tagactatga
    44281 tttggatata atggaaaaag gacaaagcct gaatgatata acatgtaaga ttttaaataa
    44341 acttcccttg attttaaaca aggaaaatcc aaatataata ttggtacatg gagatacaac
    44401 cacaactcta gctacaagtt tgactgcatt ttataataaa actcttgttg gtcatataga
    44461 agctgggctt agaacctatg ataaatattc tccttttcca gaggagttaa atagacaact
    44521 tacaggtatt attgctgata tgcactttgc tcctactaat ttggctagaa aaaacttgat
    44581 ttctgaagga aaacctaata ataatatatt tgtaactggt aatactgcta ttgatgcttt
    44641 aaagatgaca ataaaagaaa actataatca tcctataatt gatgagattg gtaacgatag
    44701 gatgattttg ttaacctctc acagaagaga aaatttgggt aaacctatga aaaatatatt
    44761 cagagctata aagcgaatag tagatgactt tgaagatgta cagatagtat atcccataca
    44821 tttaaatcct aaaatacgaa ctatagctga tgagatattt ggaaaatttc ctgaaaaaat
    44881 tcatattata gagcctttag atgtagctga ttttcataac tttttaaata aatcttatat
    44941 gataatgact gatagtggag gaatacagga agaagctcca tcattaggta agccagttct
    45001 tgtgttgcgt gataaaacag aaagaacaga aggaattgaa gcaaagacac ttaaattagt
    45061 aggtactaat gaagatagaa tatataattc agtgagcgat ttattaataa ataaagataa
    45121 ctatgttcag atgagtaaag catctaatcc atatggagat ggaaatgcaa gcaaatatat
    45181 agtggatata ataattaaaa aatttaattg caaatattta aattagataa gggctaaaac
    45241 attaactaat tgatataaga tttatgataa tattaaggaa tacaattttt aagggggagt
    45301 aatatggcta gaaaattaat aaaaaatttg ggtaaaagta aaagtgtaaa gagagtgaaa
    45361 cttttattta agaagatttt tattactgta ttcatagtag caagtatagt tgctattttt
    45421 aatataacga aatattttga ggaattatac aaagtaaggg atttaaaaag tactaaaatt
    45481 gaatactata tggatgtggc tgatgaagca ggagatggaa aggtccaatt aagttggaag
    45541 gccttacttg ctatagacat ggtaatacat gatgaagatt taagtaatat aaaaaagaaa
    45601 gacacattgg atatagggga aaagtttata gtagaagata aaaatgataa aggcgaaaag
    45661 gtgtataagg taaaaaagtt taataaggta ttaagcgaat tgaaatttga ctcttctcaa
    45721 aaaagtagag caagaaaata catgaaagat ttagaataca cataccttgg aaataaacaa
    45781 ttagatagta gtgatgaaaa aattaaattt ataaagaagt tagaagactc agctataaga
    45841 gaatatattg attatggaat attgccctct ataacaattg gacaagctat attagaatct
    45901 ggttggggaa attctaaact tacaaaacag agtaataatt tatttggtat aaaagcagat
    45961 aaagcatgga aaggaaaaag tgtagaaatt tcaacttcag agcattataa tgaaaaaatt
    46021 gtagctagtt ttaggtcgta taattcatta caagattctg tcaaagacca cagtttattt
    46081 ttaattaata ataaaagata tagaaaacat gggttgtttg aggcaaaaga ttatattagt
    46141 caagctcaat cattagaaaa tgcaggatat agtacagcag aagataaaaa aggaaatcgt
    46201 atatatgcag agctattaat agatgttatt aggagttata atttgcaatt gatagataat
    46261 aaagttgaga caaaataatt gttaacttta tatgaggaga aaacaagata agattctttt
    46321 ctacaaaaag aatagaaaaa ttgtaaaaaa aactaaaaaa atgtattgac ttgttattta
    46381 aaaggtgata ttattattac tgtactcgaa agagaacaaa a
//
LOCUS       DAEPUT010000024        46411 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.024, whole genome shotgun sequence.
ACCESSION   DAEPUT010000024 DAEPUT010000000
VERSION     DAEPUT010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46411
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.024"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            89..844
                     /locus_tag="KRL22_001496"
     CDS             89..844
                     /locus_tag="KRL22_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1271995.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            975..1997
                     /locus_tag="KRL22_001497"
     CDS             975..1997
                     /locus_tag="KRL22_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1271996.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(2161..2718)
                     /locus_tag="KRL22_001498"
     CDS             complement(2161..2718)
                     /locus_tag="KRL22_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH1271997.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2724..3800)
                     /locus_tag="KRL22_001499"
     CDS             complement(2724..3800)
                     /locus_tag="KRL22_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HBH1271998.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(3801..4484)
                     /gene="modB"
                     /locus_tag="KRL22_001500"
     CDS             complement(3801..4484)
                     /gene="modB"
                     /locus_tag="KRL22_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBH1271999.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4633..5445)
                     /gene="modA"
                     /locus_tag="KRL22_001501"
     CDS             complement(4633..5445)
                     /gene="modA"
                     /locus_tag="KRL22_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1272000.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEEKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5638..6567
                     /locus_tag="KRL22_001502"
     CDS             5638..6567
                     /locus_tag="KRL22_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272001.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFLSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6728..7177)
                     /locus_tag="KRL22_001503"
     CDS             complement(6728..7177)
                     /locus_tag="KRL22_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272002.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFSKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPHIYKKARVLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7380..8360)
                     /locus_tag="KRL22_001504"
                     /pseudo
     CDS             complement(7380..8360)
                     /locus_tag="KRL22_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(8565..9425)
                     /locus_tag="KRL22_001505"
     CDS             complement(8565..9425)
                     /locus_tag="KRL22_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HBH1272003.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRSNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(9742..11070)
                     /locus_tag="KRL22_001506"
     CDS             complement(9742..11070)
                     /locus_tag="KRL22_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH1272004.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(11218..11547)
                     /locus_tag="KRL22_001507"
     CDS             complement(11218..11547)
                     /locus_tag="KRL22_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1272005.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKYHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(11571..12860)
                     /locus_tag="KRL22_001508"
     CDS             complement(11571..12860)
                     /locus_tag="KRL22_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1272006.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLASAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(12876..13202)
                     /locus_tag="KRL22_001509"
     CDS             complement(12876..13202)
                     /locus_tag="KRL22_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1272007.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(13337..13966)
                     /locus_tag="KRL22_001510"
     CDS             complement(13337..13966)
                     /locus_tag="KRL22_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272008.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(14181..16838)
                     /locus_tag="KRL22_001511"
     CDS             complement(14181..16838)
                     /locus_tag="KRL22_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1272009.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(17197..18141)
                     /locus_tag="KRL22_001512"
     CDS             complement(17197..18141)
                     /locus_tag="KRL22_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272010.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKLLSWIEVSDGHFVYSSKSDINKYQQNLKVV"
     gene            complement(18134..19159)
                     /locus_tag="KRL22_001513"
     CDS             complement(18134..19159)
                     /locus_tag="KRL22_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272011.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(19234..20802)
                     /locus_tag="KRL22_001514"
     CDS             complement(19234..20802)
                     /locus_tag="KRL22_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1272012.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            complement(20915..21826)
                     /locus_tag="KRL22_001515"
     CDS             complement(20915..21826)
                     /locus_tag="KRL22_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272013.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(21810..22796)
                     /locus_tag="KRL22_001516"
     CDS             complement(21810..22796)
                     /locus_tag="KRL22_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272014.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            23156..23557
                     /locus_tag="KRL22_001517"
     CDS             23156..23557
                     /locus_tag="KRL22_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1272015.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKYNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            23560..23958
                     /locus_tag="KRL22_001518"
     CDS             23560..23958
                     /locus_tag="KRL22_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HBH1272016.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(24408..24632)
                     /locus_tag="KRL22_001519"
     CDS             complement(24408..24632)
                     /locus_tag="KRL22_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HBH1272017.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(24667..26034)
                     /locus_tag="KRL22_001520"
     CDS             complement(24667..26034)
                     /locus_tag="KRL22_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1272018.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            complement(26118..27653)
                     /locus_tag="KRL22_001521"
     CDS             complement(26118..27653)
                     /locus_tag="KRL22_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272019.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGMTYK
                     IDCDVILVNLFELIINNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKNEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            complement(27676..28110)
                     /locus_tag="KRL22_001522"
     CDS             complement(27676..28110)
                     /locus_tag="KRL22_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272020.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            complement(28371..29282)
                     /locus_tag="KRL22_001523"
     CDS             complement(28371..29282)
                     /locus_tag="KRL22_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HBH1272021.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            29578..29931
                     /locus_tag="KRL22_001524"
     CDS             29578..29931
                     /locus_tag="KRL22_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH1272022.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLCAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDDLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            complement(30150..31091)
                     /locus_tag="KRL22_001525"
     CDS             complement(30150..31091)
                     /locus_tag="KRL22_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HBH1272023.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGIDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(31192..32427)
                     /locus_tag="KRL22_001526"
     CDS             complement(31192..32427)
                     /locus_tag="KRL22_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBH1272024.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            complement(32471..33325)
                     /locus_tag="KRL22_001527"
     CDS             complement(32471..33325)
                     /locus_tag="KRL22_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272025.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            complement(33453..34628)
                     /locus_tag="KRL22_001528"
     CDS             complement(33453..34628)
                     /locus_tag="KRL22_001528"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HBH1272026.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            complement(34727..35611)
                     /locus_tag="KRL22_001529"
     CDS             complement(34727..35611)
                     /locus_tag="KRL22_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH1272027.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            complement(35843..36529)
                     /locus_tag="KRL22_001530"
     CDS             complement(35843..36529)
                     /locus_tag="KRL22_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1272028.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLFLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            complement(36557..36868)
                     /locus_tag="KRL22_001531"
     CDS             complement(36557..36868)
                     /locus_tag="KRL22_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1272029.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            complement(37057..37596)
                     /locus_tag="KRL22_001532"
     CDS             complement(37057..37596)
                     /locus_tag="KRL22_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1272030.1"
                     /translation="MKGMIYMIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSK
                     GLRTWEFIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAA
                     SYIQLQAHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEE
                     KKAYSDSDLDYKKVHFNHF"
     gene            complement(37675..38169)
                     /locus_tag="KRL22_001533"
     CDS             complement(37675..38169)
                     /locus_tag="KRL22_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1272031.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            complement(38203..38676)
                     /locus_tag="KRL22_001534"
     CDS             complement(38203..38676)
                     /locus_tag="KRL22_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1272032.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            complement(39002..39997)
                     /locus_tag="KRL22_001535"
     CDS             complement(39002..39997)
                     /locus_tag="KRL22_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HBH1272033.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            complement(40019..41944)
                     /locus_tag="KRL22_001536"
     CDS             complement(40019..41944)
                     /locus_tag="KRL22_001536"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HBH1272034.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            complement(41969..43162)
                     /gene="nifV"
                     /locus_tag="KRL22_001537"
     CDS             complement(41969..43162)
                     /gene="nifV"
                     /locus_tag="KRL22_001537"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HBH1272035.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            43625..44734
                     /locus_tag="KRL22_001538"
     CDS             43625..44734
                     /locus_tag="KRL22_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1272036.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            complement(45111..46295)
                     /locus_tag="KRL22_001539"
     CDS             complement(45111..46295)
                     /locus_tag="KRL22_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272037.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
BASE COUNT        15166 a         8179 c         4974 g        18092 t
ORIGIN      
        1 ctagccactg gtaacttaaa tatttcacta aaaaaaaaca aatgcaaagc tagtaccaaa
       61 aataaatcag aaaaaagagg tgttgtagat gttacaaatt aaaaatcttt caaagagttt
      121 ccctaatcca tatggtgaac ctaatactat ctttgaaaat ttatcaatcg atatagaaga
      181 tggtgaattt gtaagtatca taggtagtaa tggaactggt aaatctactt tattaaatat
      241 aatatccggg cttataaaag aatcttctgg tcaagtatta ttaaataaac ataacttgtc
      301 taatttagct gaacacagaa gaactcaaat agtaagtaga gtttttcaag acccaagtct
      361 tggaacttgc ccttctatga ctgttagaga aaacttgtct ttagctctta acaaaggaaa
      421 actattaaat ctaagaaaat gtcttcgtta caaaagagat ttcttagaaa atttattgga
      481 aggtgtatct cttgatttaa aaaaatacct tgatgttcaa gtaaaatttt tatcaggagg
      541 tcaaagacaa tcattatcac taattatgtc gtgcttaaca aatccatcag ttttattact
      601 tgatgaacat acagcagcac ttgacccaaa aacatcaaat gaagtaattg aattgactaa
      661 taagattgta agggaaaaaa atataactac acttatggtt actcacaact taaaacacgc
      721 tcttcattat ggtgatagat tgataatgct tcataagggt gaagttgtat tagatgtaaa
      781 aggtaaagaa aaagaacaat taacagttga agaaatctta gaaaaatttg aatatgcagt
      841 ttaaaataat atatctattg tattaaactc ggctttaaaa taaagttaaa attacaataa
      901 ttatggttac tttgtaataa ttcatatgaa tatatgaaca tatataataa taaatttttg
      961 agggggatat aaaaatgatt aataaaaaaa gattggcaag tttgatttta gctggtgctc
     1021 ttagtatatc tatgcttaca gggtgttcac aaggaggaga ctctggtaat tcaaaacaag
     1081 aaagtaattc taaaggtaaa gaagttaaaa aaattggtat aactcaactg gttgaacatc
     1141 cagcattaga tgccactagg acaggttttg taaaagcatt agaaaagaac ggatttaaag
     1201 atggagaaaa tattgatata gacttccaaa atgctcaaaa tgacatgcct actacacaaa
     1261 gtattgcgag taaatttgca tctgataaga aggacttaat atttgctata tctactccat
     1321 cagctcaggc agcatttaat gctactaaag atatacctat acttattact gctgtgagtg
     1381 accctgttgc tgctggatta gttaaaactc ttgaaaagcc aggcacaaat gtatctggaa
     1441 catcagattt tgtttctgta gacaaaggtt tagaacttct taaaatattt gctcctaagg
     1501 caaaaactat aggagttatg tacaatacta gtgaagtaaa ttccaaagtt caagttgatg
     1561 ctttaaaaga atatgcatct aaaaatggat ttaaagttgt tgaaaaaggt ataactactt
     1621 caaatgaagt taaccaaggt atttctagtt tagttggcaa aatagacgta ttatatgtcc
     1681 ctacagataa cttagtggct tcttctatgc ctatagtctc taaaatagct actgagaata
     1741 aaatacctgt tatagcagct gaatctggtc cagttgaaaa aggtgctctt gcttgtcaag
     1801 gtatcaacta cgaaaaacta ggttacaaaa caggtgaaat ggcagttaaa attttaaatg
     1861 gcgaatcagt atctgatatg cctgtggcta catcagatga tacagatatc attgttaatg
     1921 aagatatatt aaaagcttta ggtatggaaa aaccttctaa tgaaaatatt tcttatgtaa
     1981 agactaaaca agaatagaaa gatattttct atatacgatt aatatgcctg tttctataaa
     2041 ttaatttata gaaacaggca tatattttta ttttaatgaa ttatctattt aaagattata
     2101 tttaaatgct cttaatttgt ttgtataaat tttacttgta taaactttat acaatcatat
     2161 ttattcttct attttcttta ttactctaca tggatttcca acagctacag tatttggtgg
     2221 tatatctttt gtgactacac ttcctgcacc tattactaca ttatcaccta tagtaattcc
     2281 tggtgttatg attactcccc cacctatcca tacattatca cctattttta caggagaacc
     2341 atactctatg cctgaatttc taagttgtgc atcaattgga tgataggctg tatagatttg
     2401 aacgtttgga gctaacatta cattgtcacc tatttcaatt ttacatacat ctaaaaaaat
     2461 acaatcataa tttgcaaaga aattttcgcc tacatgtatg ttatatccat aatcacacct
     2521 aatgttttgt tctacattta tttgcttgcc aactgaacca aatagttgtc ttaaaatatc
     2581 ttctcttttt tcatattcat cctctaaagt attattaaac aatctagtta attttttaca
     2641 atactctctt tcttttacta acaattcatc atttgcatag tatcctttcc cagacaacat
     2701 tttttctttt tcagtcatat agtttactcc tttttgttat aattgtatct aaagcaaaat
     2761 aaatattcct gtggaaaatc taaatatatt ctgtcacctt tcttaaatct cattttactt
     2821 ttttccaatt ctatttgaat aggtacacat tcgttagata aatcagtttt tctaacatat
     2881 atagtatatg taaaaggatt ttctacaatg ttaatcaatt cgaaacataa cttttcattt
     2941 aaatcttcat tagaatccaa gaccttaata tgatgctccc tgattcccac atattctata
     3001 ttatcaccta tttctctatt taatgtcaac tcgcatcccc agtctgtagc ataaatagta
     3061 tttttatcca gtctatttaa tttggatata tttttacacc ctgttatctt agcttctata
     3121 aggtactttg gagattcaaa gagctctttt ttaggtctct ttggaagacc ttctcctttg
     3181 ttgtacacta taatatcatc acaaactcgg taagcttctt caatatcatg agtaacaaat
     3241 agtatatctc ccttgtaatc ttttaacata ttcataagtt ctttttccat attgcttctt
     3301 aaatgatggt ccagtgctga gaaaggttca tctaaaagta atatatctgg agatgttgcc
     3361 aatgctctag ctagtgctac cctttgttgt tgaccaccag ataattgcca agggtatctc
     3421 ccctcaaacc catttaattt aagtatatct aagtaccttg ctactatttc ctttttttca
     3481 ctcttactta gttttaaaag cccaagttct atattttgac ttacagtcat atgtggaaac
     3541 aaagcatagt tttgaaataa aaatcctacc tttctatctt gtgttgataa atttatcttc
     3601 ttttcagaat caaatagaac tctatcattt aatacaattt tacctcttgt tggtttctca
     3661 agccctgcta tacattttaa tgtcatactt tttccagaac cagattctcc caaaaacccc
     3721 agagtacctt tttcttgttt aatttctacc tttagtttaa aagaggataa atctttttca
     3781 atatccacgt ataagctcaa ctatccacac ctctttccta taattttctg ctgaaattcc
     3841 gaccaataat ttagtaataa aatcattgct atagatattg ctacaataat cataacccac
     3901 atcatagctt tattcatatc tccgccttca acagcaaaaa atatagctat tggcatagtt
     3961 tgagtttttc caggtatatt tccagctatc ataagtgtag caccaaattc tccaagagct
     4021 ctggcaaacg acagcaccaa tccaccaatt attccaggcc atgctaatgg aactgcaatc
     4081 ttaaaaaata ctttccattc attaagacct aatgttctag cagctgacaa catattatta
     4141 tcaatctgtt caaaagctga ccttgaagtt ctatacatca taggaaaaga caccactact
     4201 gctgaaatta cagttgctgt ccaactaaat attaaagtcc tatcgaaatt taataaaaac
     4261 tttcctataa atccattctt cccacatagt aataataaaa agaaacctac aactgttggt
     4321 ggcaaaatta gtggaagtgt aaatagtcca tctataagac ccttccactt acctctatag
     4381 ttagccataa tatatgacac aaatattcct attacaaaag ttattattgt tgacaaaata
     4441 gatgtcttaa gtgatatcca taagggtgac caatctgttc ccatctttcc ctccttaatt
     4501 ttaaatggaa atagtgaaac taataactct attaatttca ctatttccat tttattataa
     4561 tacacaatta ttttcaattt tcatttattt atatataatt tatacttaat tacacataat
     4621 ttatttctaa gtttattcta cttttttata tccaaattct tcaaaaatct tttgtcctga
     4681 ctcacttaat aaaaattctt caaatttctt agcagcatct acgtttttac tagctttaat
     4741 tactgaaact ggatatgtaa taggtgaatg agttttttcg tctgtttttt caactacttt
     4801 tatcttatca ttattgacag tatcactgaa gtaaacgaat ccaacatcag catttcctga
     4861 ttgcacccat gctaaaactt cttttacatc ttttgcaaat actagcttat cttttaactt
     4921 atcttttaaa tttaaattag ttaacacctc atctgcatac ttaccagctg gaacactttc
     4981 agcttcacca acagcaattt tcttcacttt atctgtagtc aaatctttca tacctgatac
     5041 actactgtca gcagaagaaa taagaactaa atcatttttt actaaatctt tcatagtatc
     5101 agaaactaat aacttctctt catccaaagc tttcatttgt ttttgacctg ctgaaataaa
     5161 taaatcacaa ggtgctcctt gttctatttg ttgttgtaat gagcctgatg ctccatagtt
     5221 aactgtaagt tttacatttg aatcaacttt tttatattct tcttcaatct ttgccattgc
     5281 ttcttttaaa cttgcagcag ccgatatatt taactctact gaatcactac ttttagttgt
     5341 tttttcttgt tttccatcat cttttttctc ttcattacta ttgcacccaa ctgtccccaa
     5401 agttaaacat gcaactaatc ctaatattcc caatattttt ttcataacaa tctccctttt
     5461 tgtaaatttg atacacattt taacatgttt tattatgttt tatcatgttt tgttatatat
     5521 agtttaatta tatatacatg ataataaatt ttcaagtaat ttatttacac tacttttaaa
     5581 tattttgcta cattttcctt tttttaatgt taaaataacc ttatatggag gtggattatg
     5641 gactcattat catctttgac acctgtcgag gtagctgaat tattaaagat aacaaaaaat
     5701 actgtatatg aattaatcaa aagaggtgaa cttccttctt ataaagtagg gaaaaaaata
     5761 agagttgata ctaaagatgt tgaagaatat atcaacagcc aaaaaactgg taaagtaaag
     5821 gatacacatt tcaacaataa aaatatagat ataaataata atttcaaaat tattatttct
     5881 ggtcaagatg taatattaga cattttagct aggtctgttg aaaaaaaatt ggatggaata
     5941 agtacatttc tctcttatat aggtagttat aatgctttgt atgagttata taatggcaga
     6001 gtttctatag catcatccca tctatgggat ttcgaaacgg atgaatataa tagcactttt
     6061 gttaaaaagc tattgccagg aataccatgt gtacttataa atctagctta tagaatgcaa
     6121 ggtttctatg ttgctaaagg aaatcctaaa gagataacaa cctgggagga tttaacaaaa
     6181 ccaagtataa ccattgtaaa tagggaaaaa ggttctggaa ctagggtttt actagatggt
     6241 aaacttagac ttctaaactt taatggtaaa catataaaag gttatgataa tgaagaatta
     6301 tcacatcttg gagttgcaag tactgtttct cgtggaatag cagatgttgg tttgggaaat
     6361 gaaaaagctg ctttacaagt aaataatatc gactttattc ctcttcacaa agagcgctat
     6421 gatttagtta ttaaaaaaga agacttacaa aatccagttt accaaactat aattaacata
     6481 ataaactctc ctgagtttaa agctgaactt caaggtcttg gcggatatga tttaactgat
     6541 actggaaaaa ctatagcaaa agtttaagat taaaatcgca atctatttta taagatttat
     6601 aatttttcac aaaatttata acttaaacac gaaataaatt gcgattttag tgtctcaaaa
     6661 aatttatgtc tttcatttta tcatccaata caaaatttaa tataattaat tgcgcaatca
     6721 tattatatta atatatattt acataatagt atttttcttt aatgtagatt aacatatgat
     6781 atgttttaaa catcaatacc cttgctttct tatatatatg tggcaacaca tatgagttta
     6841 ataaattata tacaatgttg ctttcttctt gtattttttc aaccaacaag ttatttataa
     6901 aattaccttt ctcattttca ataatctcac tccaatttat cttaactttt aatatatatc
     6961 ttcccactag gtatacacac tctacaataa ataataaaaa tacaatgcag tcagtacctg
     7021 ttgtcttata taaattaccc gatactaatg gttttgagaa gaaattataa aaattcaaag
     7081 tatcacccgt ataatcaaaa agtattaata gcactcctag aactctcaat actttaatat
     7141 tcaacatgtt tttatcttta ttatttttgt ttttcatata tactacctct cttttcttta
     7201 gatttgattg taatctaata ctaactcttt tatttgaggt ataaatgaat ttaattggta
     7261 gttattttca tttttactag aaattaattc acattactaa acaaaactta tatttaaaca
     7321 taaaaatagc ctatctattt tttaataaat acaaaaataa ataagctact aatattcaat
     7381 taacttttat cacttaaaac attactatct ataaatttaa atattttatt gaagtatact
     7441 gtactatcat gttcaaatcc atcaacatga ccaatacctt ctataagtca taggtctttt
     7501 ttatcatgtt taactaaatc atacattttc ttgctatttt gataattaca aacagtatct
     7561 tttgttccat gtataaacag tatgggtaca ttagatttct caactgactc atatggtttt
     7621 acatcactgt accaaaatcc agatttaaac ttattatata aatctccaca agtcaccaca
     7681 taattgatta atatatctgg tattcgtttt tctagtactc ccattctaat tgcatctttc
     7741 atttcagaat aaggagaatc cagtatataa aaatcgacct tatcatcttt tgaatttatc
     7801 tctgaatgca tagcagctgt ccctgccccc atggaaaatc catgcacacc taatctccct
     7861 tcaggaaatt tattttttac aaatttaact agactatcta aatcatacct ttcataaaga
     7921 ccaaatgtgt aattatctcc accactatta ccagtatttc tttgattata aactaataca
     7981 ttataacctt tatctaaata tctatatgct acctttaaca tttcatagta actacttcca
     8041 attccatgaa caagtatcat agtatctctt gtctttatat ttgaagttat aaaaagactt
     8101 tcaagcttgt aattattaga actttgtatc attaattcag atgtcttgta gttttttaat
     8161 ttctccagcg gtttatcttt tctctcagaa aatattttta ctatatcttc gttttttatt
     8221 aactgctcta aaccaactga actattatac actaatttgc caaatatata agatacaatt
     8281 aataggatta atagaaacac aattgatata attataaatt tatttcttaa actaatacaa
     8341 tttttaaaac tatttttcat atttatttac catacaattt tcctatatta tattttctaa
     8401 gtaatagcat aattgattat actattctta taatttctat tatacctact tatttattaa
     8461 aaatacaaat tatattttat taatttttac tacttgtaaa ttattatctt atacaatgaa
     8521 tttgtattat ataataagta tttttaggat tctgttacat aatattattt aaatattctt
     8581 ctatatttct cttcttcttc ttcagtaaac acattaaata caacttttaa atttttttca
     8641 ggattttctt ttagccatag tctaactcta cttacagcaa gattagctgc ctcttttttt
     8701 ggataaccaa atacacctgt agaaattcca caaaaaacaa tattttttat ttcatcaatt
     8761 tcttttattg tatttaaaca tgatttataa caatgaagca gttgcttttc ttgctcttta
     8821 cttggctgac caccagatac aataggtcca acagtatgta ctacaaattt tgcaggtaaa
     8881 caataacctc tagttatctt agcatctcca gtatattcta aatgcccttg tttttttatt
     8941 attttgtcac aatcttctct aagtctagga cctgcgcatg aatgtatctc attatccacg
     9001 catagatgta atggttgtaa acaccctaat aacttgttat ttgcagcatt tactattgca
     9061 tctgctctta aattcgttat attacttctc catatggcaa tcccttcctc tacttcttct
     9121 atatcattta catctactaa ctctctttct tcacattcaa tcaacaataa attatgtaac
     9181 atattaagta tctctggagc aatttctttt ggtggatata cattcaaaag tcctctaagt
     9241 atatctctag gcttaatttc atcatttgat aaattgtata ttttagaagg aacttctttt
     9301 gaaaaatatg caattaaagt gtttatattt tttcttcttt gttcgtcagt tagaggcttg
     9361 atagttttat caaaatcctc aaataaattt acatcatcag cataatctct ccacttcata
     9421 gccatctctc cattcttgta ttttagactt aaaaataatt atgtatttat gtacatattt
     9481 atttatttct ataaacacct acataaatcc tgttaaaagt gtaaattttt tattatgcaa
     9541 cttctctggt tatttctatt gattgatagt aaattattgt acctaaattt aatccaacta
     9601 acaagtaact aaacctactt tcctaactgc aaaatacact atgtttgcca cttgtatctc
     9661 atttgtaaat aaataaagtc cctacaaata cattaactag gctatgtact aaactgtagg
     9721 aactttaaaa atatattatt cttaattaag ttttggccaa taatttttat ttgcttctat
     9781 taaatcatct agtaattctt ttgcaactgt tgcactagga actgtcttag atagcataag
     9841 tgcttgccac aatttattat aagacttctc aatccaagca tcaactacta atttttcaac
     9901 tgctaattgt tgttctatta aacctttttg gaatgttggt attttcccta ttgataatgg
     9961 ttcatacccg tcttttccaa ctatacatgg aatttcaacc atagcatcat cttgtatatt
    10021 ttctatagct ccattatttt gaactatcaa taacatacgt tcctgtgtat taaaagctag
    10081 agctgtagct aaatccacta taaactctgc atgtattcct atcttaagcc cactgccctt
    10141 agaatgtcct tgcttttcta tcaatgcaca tgaaccaaaa acttcttttt ctcttccatc
    10201 aataacttca ttggcacgag tataatttac atcagaatga tttacaacat aatctggaaa
    10261 tagatagtac tttaagtaac tacttggtat tgtagttaaa tctgttttta ctatttcttt
    10321 agtaaataaa ttagtttcaa accaactatc tttcttgtca tttttcattc cttcttcacc
    10381 atttataaaa ccatattctt ttatatgttc tactaatttt ggtaaaagtt catttccttt
    10441 tttatcttta attgaagtat accaaccaaa gtgatttaat ccaaagtatc ttatatccat
    10501 atgtttacga gatttgagtc ctgcaatcct tgctatatta tgttccatac ctattggcat
    10561 atcacaaata tttattaccc tagaattagg tctcaacctt ctaacagctt ccgctattat
    10621 tgatgctgga ttagaataat ttaacatcca acaatttgga gaatactttt ccatataatc
    10681 tatgttttca agaacacctt ctatagacct cattccataa gctattccac ctggtccaca
    10741 agtttcttga ccaactaccc catgttttag aggtatcttt tcatctagtt ctctcatttc
    10801 aagttttcca actcttatat gagctaaaca aaaatctaca tctgtataag cctctttagg
    10861 gcatgttgtt gctaaatact ctatattagg gtccttttcc tttattagta tttcacaagc
    10921 tttagctacc ttattttgtc tttcttcatc attatcatat aatttgattg ctcttaatgg
    10981 taacctatct aagttatcta gcaacattaa tatgatttct ggggtatatg tacttcctcc
    11041 tccagctatt actactgaaa atttttccat aataatatct ccttttctat ttaaaaattt
    11101 actgtattta taaatatatt tataaatact agtactttaa agtaaaaggg agttcattta
    11161 ttaaatctat taatttaata aactatagcc aaacttcaag cactatttac aagaaattta
    11221 attcttatta attcttgggt ccatcatctc aaatatatct acaagttcag atactaaaga
    11281 atgagcaaat aatgcatttg aataatggtc ttcagagtgc acaactaaaa aatcagtccc
    11341 actatcttca ctattcatag catttgatag taattctaaa tgatactttg atgctgtttg
    11401 tattttctct gaggctgaat ttaaaaggtg ttttgcttta ttgtagtcac ctttttttat
    11461 ttccttaaga gacatcatta catcactttt agcatctcct gcttctgata ttatactaaa
    11521 tactttttct tccatttcag gtaccatatc cttctccttc taatgacttg ttaaaaatca
    11581 aagctatcat catctaatgt tgtagctaat tctgcatttt tatttaattc ttccttctcc
    11641 attatcttaa agaatggata atatatcaag gtcataagta ttatacttgc aaatactaat
    11701 acgattgcct tccaatctaa tgtcatcaaa aatgctgcaa cccctggagg taaaaaacct
    11761 ggtggttctg caataggtaa tcctactaat cctactttta atgccataaa attaagtgct
    11821 ccaaccaata caggtccaaa tacaaatggt acaaacatat atgggttcat aactattggt
    11881 gttccaaata ttactggctc atttattcca aatagtgatg gtaaaatcac aacttttccc
    11941 atactattaa aacttttaca cttacttctt gacataaggt acactaatcc caaagttatc
    12001 cctgaaccag ttacttgcaa gaaaccatag taaaatccta ttgtaaacac atattttggg
    12061 tctcctcctg ctgctatcag tgttgcattt tctgccatat atgtagctgc tattggcatc
    12121 catatacttg aagttattgc tgctccatga agcccaaaga accataataa ttgagttata
    12181 aatagtatta tagttactgc aaaaacatta tctacactgc ttatagctga tgctaagaaa
    12241 ttcattataa tagctggtag tggttgacct gagacatttt tagttattgc tgctattgct
    12301 gtaaataaca ttatacatac tatcattgga gttaagtttc taaaactttt atttactaca
    12361 ctaggtactt cttttggaaa tctaattacg agatttttat cattcataaa cttagtaata
    12421 tcaactacta aaagtgctac taatatactt acaaataaac cttgtgcatc taaataactt
    12481 gtatctaata caccatctac tacttgtcca catacaacaa gttgtgcaac aactgctgtc
    12541 atacctattt ctacatgatt aagattatat tttttagcta gtgcctgagc tataaaaaat
    12601 gctgaatata tagataataa actcatagta aatttattag ggataagtaa tgtatccata
    12661 ttttcagata ataatgtttt tgcacttcct tcaggtaaca tattgtttaa tgccataaat
    12721 aacatactta aagaaccaac aattattatt ggggtaatac ttatcatacc ttcttttata
    12781 gcttgaagat gcctttgttt ttcaatcttt tgtgctattg gaagaagaaa tcttcttaaa
    12841 ttattttgaa gtgcttccat ttttattccc cccaattatc tatttttata taattcgatt
    12901 gccgacttca taacagaagg agcatccata cgaccataat gcttagtatc tattaaacca
    12961 actgctattt tgtaattctt acaagcttca actacatcat cttccttaaa cctaatttgt
    13021 ggtgctacaa gtactacatc tgtatcatta gcttcaatgt atgattttaa attttcaaat
    13081 gatgttgcct ctatatttat agttttagtt tttaactttt catgctcact acaaaaactt
    13141 ttcatctttt ccacaagtac acctgttgaa gctccatttg cacatactaa taaaatattc
    13201 ataattaccc tcctacaata tctaacctct tttgttttct aattttttat cagccaattc
    13261 ttactctaat tcctatcagt ttttacttta attcttatta ttttatttta attcttagta
    13321 atatttactc taattcttag tactgccaat gattaaactt gaaagccgta tctataactt
    13381 cttcttgctt atatttttct aatattttta agtatctttc tttataatca ttatctactt
    13441 ctttttctgg tattactata ctagcttcat ttaaaaagtg gaatgaatcc cttcccattt
    13501 ctaatcctct atatgtatgc ttgtcaagtg ccacgtccat aacttctgga actttaccca
    13561 ttgcaaatcc ttttataatt atatttttta ataaatcact tgatctatct ttctcacatg
    13621 cacaaagata tcttattgca tgtatgaaaa ataaaggtct gtctccatct gcatatgaat
    13681 attcctttct tacttgattt aaattattta tgattattac agctgatggg tcccccattc
    13741 ctatatcttc aactgatatt gtaagtatcc ttctccatag cttatcttct aattctggtg
    13801 atgatatata tagttcataa gcaaattcac aagcttcttc caccatattt cttcttatag
    13861 ctttttgaaa tgacgatatt atttcgtctg cactaaatcc gtttcttgta gtcattcttg
    13921 cccatgggtc atttgccttt ttatctctta atattttatc ttgcatatta tttactcctt
    13981 tttatttaaa ttttaattat ttatattact catttaataa tataagcaag tattatgcca
    14041 gtttttttag acactttaaa acactgttat ttcaatcatt tttatcatca aaacttagat
    14101 actttgttta agtatattta tatgtgtcta atattaatat tattttagac taaaaaaaat
    14161 taccaaataa gtttttatac tcattggtaa tctttttcga ttatttctgc atattctaat
    14221 attaataata tttgatagca ctctttttca ttaatttcta tattatattt tttatctaat
    14281 tgagatacta tatcttttat tttgcttagg ctcttgtgat aatcaagtgt tttttcttta
    14341 tcaagctttt caatttctct agtatttcca atcaacccat ctaccatgaa agctaaatgc
    14401 atcataagtc caattacttt atcgtatttc ttttctatat taaatactaa aaacaattca
    14461 tcagacacat attttatatc tttaaatatc ctattataat tagagctttt taaggatgtc
    14521 tttaaacctt caactacatc atcataacct atacttatct ttataatatt ttttaattta
    14581 ttgatatttt catccttatc tatatctttt ttgctaatat agtcaattcc tctaatatta
    14641 attctttgtt cattgattac tgcaacaata ttactacttt ctttaagttt cgtaatattt
    14701 aaacttaaat ctttttctgt tttatatggg acagatataa tatctattcc atctaagtac
    14761 ctactcatct tttcttctaa tatttttctt gttttattat ctacaccttc tgaaacatgt
    14821 gatgctataa taattgtttt agacagattt tctttatttt gaatttcatt agttccaaaa
    14881 tagtactttc tcgtgttagt gatagagttg tatacgtcat ttaaaggtaa tcccatattg
    14941 gccttctgaa ctgcttctaa cacagttaat gtcgtcacca taggaattac tcttactcca
    15001 cacttttttt ctttctttat aatttcatca aaagagttta atgaacccat atctgtaaat
    15061 agtaatacat ctttattgtc tatattatta attaaatttt taaaatctac aattacttca
    15121 tcatagcttt tatctaactt catatcgaaa gaaatagcac tgcactttcc aataatatca
    15181 ccaactgctt ttaccatact acttgctgta gtttctccat gcatagcaac tataatatta
    15241 atgttattca ctattttatt ttgttcatct tgtttagctt gtactatgaa taatgtaata
    15301 tatgctacag tttctataga taaaaataaa tcaaattcat tttcaattat tccaactatt
    15361 tttaatgctg ttttaaattc acttctgtta tttcttctaa tttgattcaa atctatgttg
    15421 tttgtagagc tacttttatc caatacactt tttatataaa ttgccattga cttaaatatt
    15481 gattcactta tatctatttc ttcatcttct ttaataattt gtcttattga ttcacacatg
    15541 cttttaaact taacattatt aaatagagaa gcatctgcta tattcatttc tacagattta
    15601 ttaagattag tatttactgc attaataata tttatatcat tgtagttaat aacttcttct
    15661 tctcctaatg acgtaaatac aaaatattct attccatgtg ttataacttc atctgcttta
    15721 atagacttct ctctataatc atcactcact tcatttatag atttatcaaa atattttttc
    15781 tctatataaa ctggttcttt attatctctt ttatatctta ggtatccatt tgcaacagct
    15841 aattttatat cattttgaag ttgacctaca ttatttttac aatcataaag taatagtgat
    15901 ttaattattt ctttatgtac ttttattgaa atagaaatac tttttgattc ttccttgaaa
    15961 aaatttttga ctaattccat tctttcaatc attgtcctat ctctcaatga tggtatttct
    16021 attttcattg gtattcttct attgaatgta tctaatagtg ttgatgtcgg attttctgta
    16081 gtagcacata ttattaatac cttagactct ctttctttcg ttgcatctcc tagtctttta
    16141 aatgttccct tatctataaa agtaaacaac atttcttgac cttctgctgg tagtctatga
    16201 atttcatcta aaaatagtat ccctccattt gcaatttcca aaagaccttt tctggaagat
    16261 tctgcacctg tataagctcc ttgttctacc ccaaaaatat gtcccataag taattgtgca
    16321 ttattagcat aatcagcaca attaaatgtt acaaaaggag ctttattttt tctaattcca
    16381 ctatctatag aataatcgta catatatcta gcaatcatac tctttcctac tcctgtttct
    16441 ccatagataa tagtatgaag tccatttgta ggatagagca ttgcgacctt gcatttttct
    16501 attataggtc ttaaactatg ttctttacct attagtgttt caaaactatc tttttttatt
    16561 ttgttttcta cttttgttcc tttttttatg ccaagcaact cactttgtgt atcaagcaat
    16621 tcattcttgt taaggttaag atttgcaggg atataataca caggtcttcc ttttatcttc
    16681 gtaaccatac cctcattgaa taattggttt aaatatgtac ttatattgtt tcttgcaatt
    16741 cctgtctttt ctgataattg gttagctgta atcccttttt cattttccct atatgatgat
    16801 tctaaaactt tcattacttt atctttttta tatatcatta caagctcccc tacattatag
    16861 tattttatta actaaaaccc ctatacacac tttatttttt aataaactct tattctttaa
    16921 ctaaggttat aatttatcaa actttcctta ctttaaatta tagaaaatta ttgtagaaaa
    16981 aataagatta ttgctcattt tttctacatt actattttta attttatagt actttcttaa
    17041 caacatactt tacttgtttt taattttatt atatttgaat ttattatatt tgaaaagtag
    17101 aaataaaaaa ccctattttg gagtagtttt aaaatttctc caaaaatagg gttttagttt
    17161 gtatttcaaa taaatacctg ttcaagtatt tttatactaa acaactttta aattttgttg
    17221 gtatttattt atgtctgatt tagaagaata tacaaaatgt ccatctgaaa cctcaatcca
    17281 acttaataac ttttcatttg aacaatcata tccattagaa ttatactcta ttctatttct
    17341 tgacttagca tatctagggt caggaacagg aattgcagaa agtagtgatt ttgtatatgg
    17401 atgaatagga ttattataca attcatttga atctgccaat tctactaatt ttccattata
    17461 cataactcct atacggtcac taatatgtct caccatagat aaatcatgag ctataaataa
    17521 acaagttaaa ttcttttctt gttgcaattt tttaaataaa tttactattt gtgcttgtat
    17581 agacacatcc aaagaagcta taggctcatc agctattata aattctgggt ctactgaaag
    17641 agctcgtgct atgccaatac gctgtctttg tccacctgaa aaatcagatg gatacttatt
    17701 tgcataactt ctatcaagtc ctactagctt tagcatctca tatactttat tcattctatc
    17761 tgttttattt ttacagatac cttgaatttt tagtggctct gaaattatat ctgcaattgt
    17821 catacgtgga tttaatgatg aagtagaatc ttgaaaaata atctgcatac ttttgtttac
    17881 atcttttttt ataaatttgt acgttttttt atctgatatg caatttcctt tgtaaattac
    17941 ttctccacca gtagattcat gtagtcttat tatagtttta ccagttgtag attttcctga
    18001 acccgactct cctaccaatc caaatatctc acccttatat atatcaaaac ttatatcatc
    18061 aactgctttt acagtagtac ttttgtccaa atgaaaatat tgctttaagt tttttatttc
    18121 cagtattttt tctctattca ttagaaatca cccttccaca atttactcta actggtacat
    18181 ctacttcagg tgcatctggg tgcaataacc aagttgctgc actatgtgta tcattaattt
    18241 taaacattgg tggctctttt tcataatcta tcttaagtgc atttttattc cttattgcaa
    18301 aagcatctcc ttttggtggg ttcaataaat ttggaggcat tccaggtata ttatataaat
    18361 agtcatcctg cgaatctaaa gtaggtaatg aacccaacaa cccccaagta tatggatgtc
    18421 tagggtcata aaatatatcc tctacagttc ctatttctac aatctttcct gcatacataa
    18481 ctgctattct atcagctata gttgcaacta ctcctaaatc atgagttata aatattattg
    18541 acaaacctat tttatgttgt aaatccttta ttaaatcaat tatttgagct tgtatagtta
    18601 catctaaagc agttgtaggt tcatcagcaa tcaatacatc tggattacag gcaagtgcta
    18661 tagctattac tatacgttgt ctcattccac ctgaaaaatg atgtggaaat tgtttaaatc
    18721 ttttctcagg attatcaatt ccaaccaatt caataagctc tatggctctc ttttttgctt
    18781 cacttttact tataccttga tgaatgatta cagcttctgc aatttgcttt cctattgata
    18841 tagttggatt gagagatgtc atagggtctt gaaatatcat tgatatattc tttcctctta
    18901 tatcttccat ctctttttca gacttcttaa ccaaatcact tgatttaagt aaaacctctc
    18961 catttttaat atatccattg tatgggagta tcctcatcaa actcttacac agtacagatt
    19021 tcccacaacc agattctcca actatagcca atgtctcacc tttttttaga ttaaaagata
    19081 catttcttac agcctgaact tctccttctt ctactttaaa acttacagat agattattaa
    19141 cctccaataa atgttccaaa aaccatcaac ccctatgcta ttcaaacctt agggatatat
    19201 ttttatccct aaggtttcta attaatttca gtattattca attgtccagt cagctatgtt
    19261 ccagaatata cctacaccat gatgacctaa aactgtatca ggtgttaatc cttttatgtt
    19321 tggttttcca acatatattg catctatata agcaataaat gtataaggca tatccttagt
    19381 catttctact tggaattgtt tatataactt taatttttca tctttatctt ctgtttctct
    19441 tgctttttga agtattttat ctatagtagg attagagtaa gcactgtaat ttgcaccttt
    19501 atctgttcca aatactttat atgtatggtc atctgggtca aatggacttc cccaacctat
    19561 taaatgagca tcttgattag cccaatctgt ttcagttaca acaacagctt tagcatcaac
    19621 accaatttct tttaactgtt gtgcacatat tttagccata tcaactctaa cttggtcact
    19681 ctcacctgct gttatctcga aagctaactt agtaccttct ttttcataga ttccatcaga
    19741 acctaatttc caacctagct tttcaatttc ttgtttagct ttttctggat tatattcaaa
    19801 cttttctata tcaggattat tatatggtcc catttgtaaa ggtgaatatg ctggtacacc
    19861 atgtcctaat aatacactgt caactattgc ttttctatct attgcatagc ttaaagcatt
    19921 tggtaatcct ttagcttttt tatctttaaa gaatttagaa ttaaaattgt ataatatacc
    19981 tctatagtcg gctgttttca ttatatttac tttaaaattc ttttcgtctt tttcaaagtt
    20041 agacatatct ttaggagtta tttgagctag gtctaattct cctgatttta attgcattgc
    20101 cttagcctta tcatctggaa caatcttaaa gactacttta tctaatcctg gttcttttac
    20161 aaaataatca ctattcttaa caagtgttat actttgacct ttgtcccatt tttcaagttt
    20221 aaatggtcca gtacctattg gtttttgatt aaattcatca gtagctatat ccttaccttc
    20281 caaagcatgt tttggtaata ctcctactgt taaataatca agcattgctg tatttggagc
    20341 ttttaaagta atttttatag tattatcatt aaccacatca atttttgtta tatcttcata
    20401 atttgatgct atctcagaag cattatctgg attcattata gtttctattg taaacttaac
    20461 atcatttgct gtaaattttt ctccatcatg ccacttaaca tcatctctta aattaaaagt
    20521 atatgtattt gttgcctcat caaatttcca gtcctttgct agacaaggaa ccaccttatt
    20581 attttcatca tgagctgtta atccattaaa tattaacgaa tttatttctc catgttcgta
    20641 tagtgcagga tttatacttg tatagtcatt acttccataa acaagtacct ttccatcttt
    20701 aggcgtatct gccttcttat ctttgtctcc tccactagaa caacctgcca ttagactaag
    20761 tatcattact aaacttaaaa cttttaactt ctttaatttc atgatgctcc cccttttgct
    20821 ttttataaaa tatttttcaa agctttgacc ccatttattt aaatagatat ttcaaatacc
    20881 tcagtatttg cttatttaat actcaaatgc tgatttataa attactagat tttttattat
    20941 tattctttct tatataatta cctatatttg ttatacacac caatgtggta accaaaaata
    21001 tacccggaat cagtataatc caccatctat ttgaaagtaa tgcttcctct gacaaagata
    21061 acatacttcc ccaagaaaca atttctattg gtaaaccaat tcctaaaaag ctaagtgtcg
    21121 attcagtacc aatagctgcg cctatgtttg ttacaaccat gaacattatt gatgccacaa
    21181 aatttggaag taaatgttgc tttaatacat agaagaatcc tcctcccatg ctcttagctg
    21241 ctagtatgta ttcgctattt tttatttgtc taacttctgt tctcactatc ttagatatat
    21301 tcatccaact tgttatccct attactatgg acatagatac tggatttgaa tttccaagta
    21361 tagcttgtac aaatattata attaatattg aaggtatact aagtatgatt tctgtaaacc
    21421 tcatcattgc atcatctaca agttcagatg ctgaaccact tatactacca taaacaattc
    21481 ctataacagt tgatattaca gtggaaaata gtcctataaa taaagatatt tttcctccat
    21541 accatatcat agaatatata tctctaccca ttgagtctgt tccaaataaa aaagttttat
    21601 ttggagctaa attagaactt gctaaatcca tgtatgttgg ttcatgtgtc attataaaag
    21661 atgagaatac acttccaatg actatgattg ataaaataat aattgatata tatggtaatt
    21721 ctttaatttt tttagataag gttttctttg tttctatatg ttcatcttct gctactaaaa
    21781 tataattttc tcctacaatt tcaaaatcac tatattgtgg cttcattagt atcacctcta
    21841 tcatatttca ttctagggtc tattttattg tttataattt gagctaacat attcccaaat
    21901 actactaaag cccctgttat taagcataaa actaataaca tattataatc atgatacttt
    21961 gcactttcaa aacaaagtgt tcctaaccca ggataagaaa aaactttttc aactacataa
    22021 gttcctccta gtatatgagg tatcgaaatg gccattatac taatatatga tggcattata
    22081 tttctcaggc aatgcttaaa aacaatagtt ctattattta aaccttttgc tttacataaa
    22141 agcacataat cttctcttat ttcctctagt aatttatttc ttatcatata tgtgtaatac
    22201 catagatggc ttaatataag tactgtaaga ggtaagatta gatgtgatat cctacttaat
    22261 atactggact cttctcccat tgaataagca ccactacttg gaagtatact taagtttata
    22321 ctaaatataa gtatgagtac taaggcaacc caaaatgatg gaatacagtt ggttattgtt
    22381 cctaatttgc atatgattct atcaatgagc ttatcttcat gtaatgtaca aaatattcct
    22441 aacaataagg ctagcacaaa ggtaagtata tatcctgaac cacctaatat tatagtgttt
    22501 atatagacat catttataac agaagtaaca ttttgtttat atttaaatga aattccaaat
    22561 tccccttttg atgcatttga aatccatttt atatattgac tgtatattgg ttcatccaaa
    22621 ccaagttttt tcatagcatt ttctttttct tgtgtactca ttctttctac tccatcccca
    22681 tagtaagaga ttaatgggtc tcctggagca agtcttgcca tgtaaaaaac aataaaagat
    22741 aataaaaaca ttactaaaat aaactgcaac aactttttca atatatcctt taacaaaccc
    22801 caacccccct ttgttgcaat aaaaaaaacc acataaaagc aaacgtaaag taacgttaaa
    22861 accttcgtgg ttccattatc attaaacaaa attaaatttt ctatatttat ctatgagtta
    22921 attttagcat catttattaa ctgtgtaaac aaacttttta aaaattgtta aaatttcatc
    22981 aaattatttt atttatacct aaaataaaat ttttatattc tattcttcat tattttctat
    23041 aaaattataa aattttaggt tgactatata agaaaagtat attatattag tttgtatgca
    23101 aaccatttaa gaggtgattt tattgaaaag taattatgac tgttttagaa tagccatgct
    23161 cttaaaagaa ctttattcta aaactatgta cacagtagaa gaaaatttta aagaaaatgg
    23221 attaacacac caacagatta tagttataaa actgatagct cataatcaag aacttacaat
    23281 atcacaacta tgtgatgaaa tgtctttagc taaaggtacg gtttcaggca taatcagcag
    23341 attagaacag attggatata tagaaaaatt caagaaatat aatgataaaa gaaatacata
    23401 cgttaagttt acaacaacag gatttgaatt tgccacaaat tttaaaatta aaatgcaaga
    23461 aagttttgat gatattttta aaaattgtga tgaaaacgaa ttgagtgact tagtaaaaaa
    23521 tcttagaaat atattggcaa aagtaaagga gagataatta tgaattataa attaatactt
    23581 gcaatagtat ttataacatc agctttaatt ttctacacta taggtgtatt tggagaaaga
    23641 aaggcaaaaa ttttaaaaaa gaaacatgta attatatttt ggcttggttt tatatttgat
    23701 actttaggaa catttacaat gagtaacata gccaacagcc atacttttga agtaaaatct
    23761 gctttatcac aaaaccttca tagtattaca ggtcttcttg caattgtgct tatgcttttt
    23821 catgcaagtt gggctacttt tgtcctatac aaagatgatg aggaaaagaa aaaattcttt
    23881 cataagttta gtatagttgt atggactata tggttagttc catattttat aggtatgttt
    23941 attggtatgg ctggatagta aaataaaaag tgtgtaagaa atactgtagg taaatttgta
    24001 taagacaaat ttatctacat ccttctttca cacttttaca tatttattta taatactcca
    24061 ttatttcttt catgtttctt aatacctata tagaatattt aattatttct atagtatttt
    24121 attattttct cacacttttt catatatata ttgttttact atttcttcat atgtatatat
    24181 gaaatattcc attatttcta taaatgtttt attatcttta tcatactttt tcatatatat
    24241 attgcttcac tattttttct tatttcttca tatacatatg aaatatttca ttatttctat
    24301 aatgttttat tatctttatc atactttttc atatatattg cttcactatt ttttttactt
    24361 ctttattaaa tacttatgta taacatacat ttaataaacg ctaactatta aacacctaat
    24421 acttgagtta ctcctggaac ttcactcacc aaaacatttt caataatagc tttgattgtc
    24481 atagtcgctc ctggacaccc actacatgcc ccttgtagtc taactaaaac cacaccattt
    24541 tcatttacat ctataagctc tacatctcca ccatctcttt gtaatactgg ctttatcttt
    24601 tcctcaagca ctttctcaac tttttctctc atagctattc cccccagaaa tattttatta
    24661 ccaaaattat accaatggtt taaatttttg tccatctaat gatttatcaa attcaatttt
    24721 tgcttcatca ataattttag tatccataaa tacatcataa gcactacaag ccagtacttt
    24781 agctgaattt atcatagcag aaaatcctat atttgaacct gctgatgaac atgactgcca
    24841 tgtatgactt gcaattccaa caggccaagc tgccattgca aattgagcca ctggtattac
    24901 ataacttaca tctccaacat cagtagaacc agctagtcct ttatctttgt caccgtcaac
    24961 tatttccttg tgtatatagc tttctacaat agatttatca ttttgtaatg atgttgctac
    25021 acctaatctt tcttctctag taagagtatc acacaacttt tttgcaaatt cttcttcttc
    25081 aggagtattt ttagggcaac caacaaaaac catattgtca taaactaaat cagtcaaaca
    25141 ttggtttggt atatagtcat atattccatc tgtaacctta tactccattt cagtttctgt
    25201 catcattgct gctccttgag ctacttttat taatctatca agaacgtgtt ctgcatcctt
    25261 tgctttttta cctctaataa agtaccaact ttcagcaaat ccaggaacta cattaggtct
    25321 tccaccacca ttagttataa catagtgcat tcttatagag tcaataacat gttctctcaa
    25381 ataattagct ccaacattca taatttcaac agcatcaagt gcgcttctac cattatgagg
    25441 agcttgagct gcatgggctg ttatcccttt aaatttaaat tttacagata agtttgccag
    25501 acttccacct ctccaaggtg catttatatc aaaaggatgc catgtaaatg cacaatctac
    25561 atcatcaaaa cagccattta tacacataac tgtctttcct ccaccttctt cttcagcagg
    25621 acaaccaaaa tattttattg ttccattaaa tttattttct tctattaatt tttttataga
    25681 aacaactgct cctacacctg ctacacccaa caggttatgc ccacatccat gtccagcttt
    25741 tccttctacc aatggctttc tttctgcact tacacattgt gatagctctg gtaaagcatc
    25801 atattctcca agtatgccaa tcacaggttt accctctcca aaacttgcta taaatccagt
    25861 aggtaaattt tctacttctt caattttaaa tccttttgac tttaggtatt ctttttgaat
    25921 gctacttgca tacttttctt caaaggctaa ttctggattt tcccatattt tcttagataa
    25981 atcaattaat tcttctctta tttcttcaac attatttatg atatactctt tcataatttt
    26041 cctccaaata tatgtatttt tgatatgctt tacagattat attatatact aatattctat
    26101 ttattcacaa ttttttgtta attaatttta ttcatatgct cttctatgga gtatatctta
    26161 tcttcacttt gcctcttcat aaatttaatg tactctatct tccataaagt agtttcagtt
    26221 ttctcattta acataaattc taatatatta atttctctca ttctaatatc ttcataaaat
    26281 actacactac ccaatattgc caattctaat tcacttaatg atgcaaacaa cattaaatac
    26341 tcttctccaa ataaacattc agattcaaga atatcgataa agtctttttt agcattgata
    26401 ttttccttta ttattcttat tttttcaatt atagatgtac tatctaatat ctcattgaat
    26461 atctctctaa acgattcatc atccaattta ctttcatcat caacaatata atcttctaag
    26521 tgttcatttt tatttttact cacagttacc atacttttaa aagtgttact ttttattgag
    26581 cttagcacag attcaataaa tatcttttca tattttttaa tatatcttat tacatcttca
    26641 tcttctatac ttaatctttt tattaatact tcaattgctt ccataagtag taaagttatt
    26701 tttttattta ttctaatttc tctgttaatt tcttcaaaat cattataatc caaattacta
    26761 tctacttcag tgttaaaact atcatctact tcaatcaatt caattatatt actttcttca
    26821 gagtctataa ctttatcttc agtaatatta ttgtacatat ttttaaattg tttttctaaa
    26881 aattcatact catattttga aatttctaaa ttagtcactt catttcctaa aatagtagaa
    26941 aaaatacaat tatttataat aagttcaaat aaatttacaa gtataacatc acaatctatt
    27001 ttataagtca tcccatagtc ataaaataat ttttctctat cttttttctt aaataggtta
    27061 caaaatctat tttctatatc tatactctca atataattct tcacataata aataccctta
    27121 acatccatat catctagtgc caatggataa tctatactta ctggaacgtc ctgagcttca
    27181 aattttacaa tataactttt aaagaaactt gataactcca tcaaggtatc attatatgct
    27241 attgaattag tatccaattt tctactcatc attagtttat aaaaatcttt tagcctaact
    27301 aactcttcct ctaatatttc aattcctcca aggtacactt ttttaacatt cttagcagtc
    27361 aactccacaa ctcttttttc tatatctcca agcttattta tatatgcatc aatagcatac
    27421 catattgaaa tcaacagttt ttcggcaact tctgttttta ctgatgtgct ttgaccattt
    27481 gtatattttt taatcaaatc cataagtatt agagatattt cttgttgtat attatatact
    27541 tctctttcat ctatcacttt acaatttaga cattccttaa gtagagatat ggaatattgg
    27601 ttctttatta aattattttc gtttatatta atattactta aattatttaa catacaaaat
    27661 ctctcctatc atatattaaa cttctccaaa tttaaatttc tttgcaaatt cgtctgcttc
    27721 tcctcttaca ttgtccatat tgcctgaaaa tttttcataa aattcaccca gtatttctat
    27781 aatctcatca tcacatatct tgtcatcagt ttcatttttt aaataataaa aaatttcttg
    27841 catatcatta atagcctcta aataattgtc cacatttgta tattgtgatg tatatatatt
    27901 ttctattaac tgttttgtaa cttttatatc taattctatt cttccatacc cctttaaagt
    27961 attatctctc gaatttatta tatcttttac atcagattca gaaagagcta gaccataatc
    28021 tccagattct atattagttt caagcagttc atttctttct atttccttta aattctgatt
    28081 tatagaactc aaaataatag gtgatatcat ttttaaattc tcctttttta ttttttccat
    28141 tgactttttt tgttttttat gctatactta agttaatata cattattttg caaaccactt
    28201 ataatagtag tgttaaaagt ggtttttgtc aactcaaaat tactatctca attaaacttt
    28261 tcaattttct caacaaaaaa aataccatca tttagatata taattttcta taacaacttt
    28321 taattcagta gttatttact aaaatctaaa caatgatata tttattaatt ttatttatct
    28381 tttttggctc tacttctact tttctttaca tttgagcaat ttctacaaga aggtgaacag
    28441 tattgagatt tagaatttgt aggaatataa attttaccac agtacttgca tttatttaaa
    28501 gaagaaggtt cacttgtaat tgcaaaggca tagatagtct caatagctgt tttcaaagaa
    28561 tcaaactccc atgcaataat tggtttatct aattggctta tagaaaatcc tatcttttga
    28621 ggattaaacc ctccagacat aatagtaaca ctttcagtta atagattaga tgtattttta
    28681 tatacacaaa tttgattaaa atgcttacac atatctttag caaaacttac aatccaatct
    28741 agttgttcag tgtagaactt tgaaaatact aaatctaaaa tcaatggtct ctttccaaaa
    28801 aactttggag attcttctct ctttgataca tctatacccc ttctatactt tttaaaatac
    28861 acatcttcat cacttgcaaa tggtataaac atgtttacat attcatctgt actcaatata
    28921 ttctcttttg taatataatt cttttcaatc atcagtactc tttcttctcc aactatatct
    28981 ctattatata cacttgaata tattaaaccc aataatccat acttttttac aaattcaagt
    29041 acttctttct ttagtttcat ttcttttgtc tcttttgata tatcttgtaa tgcctcttgt
    29101 cctatgcgaa ttatatctac tattatatca tctgctacat caaatgggtt atacatggta
    29161 aacacagcat cttctgttgg aactatatat aattcatctt cttcagtaat tttatattca
    29221 taatcactat acctaatcca atcacttgca aaattcccta ttaattctat ttttttattc
    29281 ataataatca ttcacacctt tcaatgtaat atataatttc atattactat tacactttta
    29341 gtttattcca tattttctac actgtcaact attcttttta tatttttagc atattaaaat
    29401 ttataatagc ctttataatg gatttctaca gctaaatttc ttatttattg atgactaatt
    29461 cataattaaa tttataaaaa ctatttacat ataaaattaa tttctttata attgatatgt
    29521 aatatatttt tacacttaca tattacatat caattataaa gagaggtatc taaaatcatg
    29581 gatagaaaac gtgaattaaa acaattatac aaagaaatga aatttgacac aggtgtattc
    29641 ataataaaaa atgatattac taaaaagatt taccttggaa aaagtaatga cataaaaagc
    29701 aaatttaact ctctcaaatt tcagctttgt gctggctcat gtatgataaa agaattaaat
    29761 aatgaatgga aaaaatatgg tgaaaaagca tttacatttg aagttttaga acttataaaa
    29821 catgatgata acaaaacaga gaaagacgat ttagaagaac tagatatttt agagatggtt
    29881 tggttagaaa aattaaagga agataatact tatgaaattt attccatata aaaaataata
    29941 taatataaga aaaggagata gtatatcaaa atagacattt agttcataag atactttttt
    30001 atataaaata aagtatcttt tcataatttt aacaatgaaa aagaggctta tctccatttg
    30061 atagcctctt cccatatatt ttataccatt ataaaatgaa caatctacta attttcaatg
    30121 tatatattca ttttactaat aacactccat tacttcttta cagcatccaa acattgctct
    30181 ataatactct tatcacttat acctattgct gttactttac tagctccact taatatactc
    30241 ttatcacttt tatttgaaac taaaacaaca ggagcatttt ttgcaagtgg tgatgcaact
    30301 aaagcataaa ctaaatcgtc tccacttgtt atatagaact cttttgctcc attatagaac
    30361 ttttcaataa catttttatt agtttgatat ctatcaatac cgccaattct agttgctcta
    30421 tatctgctca ctatgtaatc acttaatgta gactctcctc caatagcata tactggaaca
    30481 ggagaaacac caaaccatgg gtctaagtct gtgtcttctt ctgctgaagg tatatctttt
    30541 gtcaatatta taggagctcc atctctataa gcaacagatg caacacttac tgcatcagct
    30601 tcatccttaa atccatttac taaaaacatc ttatcactgt ttttaatttt ttctatttca
    30661 cctgcaattt tataacttgt atctactcta tctacaccat caattcttat aacttgcatt
    30721 cttctcataa gtaacatttt ttctacatct ttacttatag aattttctcc acctattaca
    30781 tatatcttag taactctatt cagtctttga agcgttgctt ctggtatatc atccttatta
    30841 gttaataaaa tagctgcatt atttactcct gcaagaccac ttgcagcaat tccatctacc
    30901 attgtagagt ctgcattgat aagaactgct gttgtaaaat cttgcttatc tgaaataagc
    30961 ccagctgttt catatttatc tactccttga atattttcaa tcttatctag tgcgtttatt
    31021 gatgttggaa aactaacact taacagtaat gctgaaatac ctaacgccaa taccttttta
    31081 ctaatcctca taaattacct ccctaaaaca aatatattta gtattagtat aatataaaat
    31141 catttaaaaa tagtgtaaaa atagttacac ttttttataa tttaaataat tttagactaa
    31201 acacaattca tccattaaaa taacttcatt tattctatat gctaagccat cccacgtttt
    31261 ttttgacata tctacagatg ttttcttatt tgagttattc aataaagatt gtatcttaga
    31321 atctattgca ttatacaaat tattttcaaa atcatataac tcttcatctt ttggaatacc
    31381 ttctttctcc ataaaaggta gagaaacata ttctatcttt ccagaattat taatctcact
    31441 accaatccac tctttaacac caagaatatc agtagtgatt acatctgtgc cacaagataa
    31501 agcttctaaa actacaactg gtaatccctc ataaaatgat ggtaacacaa atatttgtga
    31561 cctgttgaat agctcagcta aatctctctg ttctaacttt cctaggaaat tcattttaaa
    31621 tggagactta cttgccagtt taactatctc attatatgat tcgatatcgc ttccagtacc
    31681 tgcaaaattg acttctatta aatctttact atattttaat ttagatatag cttttataaa
    31741 tggaatcagt ccctttgatt tacatatctt acctgcaaat actattttta ttttatcatc
    31801 ctttatttta taatttttat tataaaatat atcatcatta taaccactac caattacaac
    31861 tactttactt tcacttactc caaaagtctt tataatatca tatttctgat tttcatgaag
    31921 agcaaatatt aaatctaatt tccttatatt tgctattatg tattctttct ctaaatcaat
    31981 ggtatttaac tgtcttaaac aagttccatg acaaatagac ataaccttta tatcttttac
    32041 catttcccta acaaatgcag ttaaaaggta caaatgatga catattataa gttctggttt
    32101 aaaatcattc atagccttat ctatatttac tttaaattga tatttcaatc tatttatcat
    32161 gtctatattt aaatctttat atcttgtact ttcatatggc atagaatcac tcatacctac
    32221 aacaggaaaa tttaactccc cacaattata ctttactgga taaaaactta cttcacttgg
    32281 aaaacaattt acatcatcat ttacatctat acctgcaatt acagcttgct tatgaccgat
    32341 tttttcgaac ccttttatca taccagacaa atatatacca ctacctgtac tatttggttt
    32401 ttgtgttatt atatgaagaa ttttcacttt tcacttgcct cctttctaaa attaaatagt
    32461 tttatacagt ctaatcatta tatatatcta aatataaaca agatgaatca tcttttactt
    32521 taaatcttgg cactttaacc gctttatagt cattatcttc aaaatccctt actttattat
    32581 gtatatatcc tataccaaat ttttctgcta tacgtatcaa ttcttcttct tttattagat
    32641 tatatctatc acatgcactt gtaaaaccat cactcgttag catcaattga aaatcttttt
    32701 ttatttcaat gtatccatat atagaatttt ccacagcttc ctcatcaaaa tccaatatcc
    32761 aatagccctc ttttgtattt ttcttcaatc tattgcttac tattgtatcc ataacactag
    32821 ttctaatctc atcaaaagcc atctcttcca agttagaaag tttactcatt tcatcaaata
    32881 cagtattatc aaatttacaa atactcctat cttttataac tttggaatct ccatttttaa
    32941 taaacaaagc acaatctcct aataaaaaat actctacttt attttcatga aattttacaa
    33001 caactataga actagatggt aaatctaatt tttcaacctt aaacccattt aatcttagtt
    33061 catactcttt ttttacttct attattccag tattaataat actctttaat gattcttctt
    33121 tatttatatt tttatataaa tacctattcc accactgaac ataccacctt gcgtcacttt
    33181 cagttgacac taaatttttt ccattaagtc ctgtagcacc atctaaaacc catgcgccaa
    33241 atggatttat accgactaca tcttcattaa atttagctgt tccttgatta cataataggc
    33301 tatagtttct tatatttaaa gccatatcaa cctccaaatt gaatatctaa aaataaagtt
    33361 ctatttaaaa ttatacagca aataaaaaaa tctacaacaa aacttgttgt agatttttac
    33421 ttaatctata ttatctttat actttcagta ttttaatgat ggaataatct atttttagta
    33481 aatgccatga ctatgttata cttattacaa gttaatataa cattatcatc acgaatagaa
    33541 ccacctggtt gtgctataaa acttactcca cttctttttg cacgttctat attatctcca
    33601 aatgggaaaa atgcatctga accaagtgct actcctgtta aagttttaag ccatgctctt
    33661 tttccttctc cagttagagg ctctggtttt tcttcaaaaa agttttgcca tatgccatca
    33721 gcaagcacat ccatataatc atcagaaaga tatacatcaa tagtgttatc tctatctgga
    33781 cgacctatat cctttttaaa ttttaagttt aatactttag gatgttgacg aagataccaa
    33841 gtatcagctt tgttacctgc aagtctagta caatgaatac gtgattgttg acctgcacct
    33901 acccctatta cttgtccatc tttagcataa caaacagaat ttgattgtgt atattttaat
    33961 gtaataagag ctataattaa atcacgtttt gcactatctg taaaaatttt attatcagtt
    34021 ggaatatctt ttaataggtc ttcatttatt aatatttcat ttctaccttg ttcaaaagta
    34081 attccataaa catcctttgt ttcaataggt tcaggagtat aattttcatc tatttttaca
    34141 atattatagt tgcctttacg ctttcctttt aatatttcaa gggcttcatc tgtatatcct
    34201 ggagctatta taccatcaga aacctctctt gctataatag ttgcagtctc cttatcacat
    34261 acatctgaaa gtgctataaa atcaccataa gaagacattc tatctgctcc tcttgccatt
    34321 gcataagcac aagctaatgg agaaagctct aaatcatcaa caaaatatat ttgctttaaa
    34381 gtatctgata aaggtacccc tactgctgct cctgctggac ttacatgttt aaatgaagtt
    34441 gctgctggaa gacctgtagc ttcttttaat tccttcacaa gttgccaact attaaatgca
    34501 tctaaaaaat ttatgtatcc aggttttcca tttaatactt ctataggaag ttctccattc
    34561 ttcatataaa tctttgatgg tttttgattt ggattacagc catactttaa ttctagttct
    34621 cttgccatat actcatccct ctatataata aattaatcat aagtttgatt aatcctatat
    34681 taattaaatt attcgtacta ataaaattat atggcatatt tatccattaa tcaactatat
    34741 tttttaaaac tcctattcct tcgactttac attcaactat atcgccatgc tttaaatata
    34801 cttgaggatt catccccata gcaacccctg ctggagttcc agttgaaatt atatctcctg
    34861 gctttagagt cattcctctt gataaatcat ttattatagt aggtatatca aatataaagt
    34921 actctgtatt agaattttgt cttacttctc catttactac actacttata tctaatttta
    34981 aaggatgttc aaattcttct ttatgtacta tacaaggtcc catagatgta tgtgtgtcta
    35041 agctttttcc tctaaaccat tgaacatgtt tatcttgaag tgctctttca cttatatcat
    35101 ttactattgt atatccaaat atatattcat aagcatcttc ttttgatata tttatacctt
    35161 ctttacctat gattactgca agttctgatt catagtccaa cttctctacc aaatctccat
    35221 gtaagcttat cttatcatcc actccaatta ttttgtctgc tctcttagaa aaataaattg
    35281 gataatctgg cataactacg ttttttataa ctccatctgg gatttcattg acatggtctt
    35341 tatagtttag acctaaacat ataatatctt ttttaggtct tacaattggg gaacataatt
    35401 taacttcttc taacttataa cactttgcgt tttcaaatga attgtttttt attttttcta
    35461 aatctcctgt agatacgttt tcaataaaat cattcatatc agtatataat ttacttaatc
    35521 ctaaactatt aatttcatat atactatttg tttctgaatt aaatacacct attttttctt
    35581 cattgctact acaaaaagtc acaaatttca tttttattcc tccattcaat aagttgatta
    35641 atattattta atttttatta gtttatataa attgtaattc ataatattta tatgtcaata
    35701 catatttata tattttaaaa atattcaaat aatttttatt aaatttatta gttattaata
    35761 tataagtgct ttataaaaca caaataaaat aaggttgatt taaaattaaa tttaaaacaa
    35821 ccttataaac cgattatact atctacctaa taaatatagc aaataagctc ctcaataata
    35881 tacaaaaccc tacatctcta aacctatact taactaatcc aagtacaata ccaaaaacag
    35941 tacctatcat aatttttgaa ataataactt caaaggtgta gctcgaattg ttatacaata
    36001 ttacataatt tcttataaca tctatgtatc ctatattata aattccagat agtatagatg
    36061 ttatacagat aattttactc tttgacttta taaaattact tagatagttc catatatatt
    36121 ctctaaaaaa taactcttca aatattggga ctatcaatac ggacaaagtc atcatagtta
    36181 cattaaaaag tacatatccc ttagtacaat aagttacaat tattgctaaa aataaaacca
    36241 caacaaaaag tatcagctta cacttttcaa taagtatatt gtttttattt tcttcaaaag
    36301 cttctgtgat ttttctattt ctaaccttgt tatacaaaga attatctttt aaaaataaaa
    36361 ttaacgataa accaactaat gtaaaagaaa ttaagtttat aatattaaaa ttttcaagag
    36421 taaattcaaa ttgacttaga agtacataat tcaaaatcat ccttaatatt tgaactataa
    36481 acatcaataa aatagaatct attatgcatt ttttgtaact atacttcatc ccaatttaaa
    36541 tcaccccatg tatatgctaa tcgtaaagtc catttaatac cctacttaca gttgctttgc
    36601 tccaacttgt ttgatttgaa atttctttat agcttaagcc atctcttctt aaactcttta
    36661 tattatttat atcatcatca gtaatttgtt tttcttttgg cttaaggcta tttttatagc
    36721 ttcttagtct atccaattct gatttcaaac tatctacctc aaactgtttt ttttgaagtt
    36781 tactctcata agaatctctc atttcattaa actctttaat gtagtttact ttccagtcct
    36841 catccatttt tgttttaaat atacccatac tttaacctcc ttaaattttg ttactcaagt
    36901 tatgtatcga ttataaacat taatttctat atttatcttt aaaatccttg tacataaccc
    36961 ctagataagt tagtaaaatt cagatatatt tttacaattt taagtatata ttaacaatag
    37021 aaaaaaatat aatgtcttaa tacaacatat tatatactaa aagtggttaa aatgaacctt
    37081 tttatagtct aaatcagagt cactgtatgc tttcttttct tcatcaggat atcctataga
    37141 aattatacat tctacactgt acttgctagg tacttttaat tcttctctaa tgtacttatc
    37201 agcttctata ttatcatcat gcattctatt tcttacttgt atccaacaag aacctaaacc
    37261 tagttcatga gcttgaagtt gtatgtatga agcagctata cttgcatcct ctatccaaac
    37321 atcatttttt tctttatctg caataattac aatagctaaa ggtgcatttt ttaagaaaaa
    37381 tccaccacct ttagttctac attgagataa attaattagc ttttctttat catctaccac
    37441 tataaattcc catgttctaa gcccctttga tgatggagct aaaagagcag cttttaatat
    37501 tttatctaat ttttcttttt ctacttcaac atccttgtat tttctaatac ttcttctttt
    37561 ctttagaaat ccaatcatat aaatcatccc tttcataata gcatacacta ggttatatta
    37621 tgcccttact aatgctgaaa atctattatt taccccttgt attgtaaatg ctctttataa
    37681 tattttatca taacagtaga aagatttctc ctttcctaaa aaactcattt ctccgatttt
    37741 tataaaacca cactttgtaa gtaataaatt catttttgag tttattgaat atgtatcgct
    37801 ctttaagtat gatacattgt tttctacagc taatttttca gcaaaatcaa ctaacttaga
    37861 tgctattcct gtctttctaa agtttggatt tacagccatt ctatgtatta ccattgcttt
    37921 tttattagat gaccaattta agcctaaata ttcttctggc tcttcataat taagacatat
    37981 aaaccctgct acttctccat ccacttcata aatatataaa tcttgtttct taatatctga
    38041 aacaaagtct ttttctaatg gatagttttc atcccattgt gtattattat aagtcttcat
    38101 ttcttccact gtagatttta taattttcat aatgctttct aaatcattca tattcgcttt
    38161 tctaatcata aaaatatctc cttaagttaa tgtatttatt tactatctct ttactttaaa
    38221 ccattcattt tctacgtttt tgctcatttt ttctaataac ttagttacca cttgtttttc
    38281 ttcatctgta aaattatcaa aacatatctc tatacttcta ttctcttctt caattatcaa
    38341 ctcataaact tccaaagatt tatcagttgg agttaaatta tatcctcttt tatcaaactt
    38401 atcctgcttt ttatctacat atcctgcctt tattaatttt tgtatagcct tggttgttgt
    38461 agccttgtct acctttaaca tatttgataa ttccacaaga tttataccag gattttcaca
    38521 gattcttgtc aaaaatgtaa attgtccttt ttgtaacttt aattccttgt acttaatatc
    38581 atttattgaa tttactgctc tagataaagt acctacttct cttaatatat tactatctaa
    38641 agtcttaatc aaacacacct ccactgaaac taccatggct aaagtcaaat agtttctgtt
    38701 ttatagaatt tcacataatc aatatattca tttttagttg aaagttcaac ttttttaaat
    38761 tttaccatat tttggttgaa agttcaatta aaaataataa atttatttaa tctttctttg
    38821 cgtattaatc aattaatttt aaaattaaaa tggatatccc aaaattaact ttttcgttta
    38881 tgaggaactc tcttttgtat aaaatcaaat atattttatc attccaataa aaaaggctta
    38941 tctctatttt gagaaagcct ctttccttca atctatattt tactttttcc ctaaataaaa
    39001 tctatacaat atacttacac acctcatccg caaactctgt agtagaagct gagccaccca
    39061 aatctacagt caatttactt ccttcaagaa atactttttc taaagctgtt tctatttttt
    39121 gtgcattttc atattcacct aagtatctaa gcatcattac tgatgattga ataagtgctg
    39181 ttggattagc cttattttga cctgctattt gtggagcact tccatgaaca gcttcaaata
    39241 tcgcacaatc tttaccaata tttgcacttg gaattatacc taaacctcca acaagcccag
    39301 cacctaaatc tgatagtata tctccataaa gatttggcat taccattaca tcataatttt
    39361 ctggatttaa aactaagttc atagctgctg catctacaat caaatcatca tattctacac
    39421 catgttttga tgcaacttct ctaaacacat ctaaaaacaa tccatcagac attttcatta
    39481 tatttgcctt atgtatagct gtaacttttt ttctcttatt atctttaaca tagttacatg
    39541 caaaatcaac gattctttca cttgcacttc ttgttattat ctttatactt tcagctgcat
    39601 aatcacctat tttatgttct attccagcat ataaatcttc tgtattttct cttacaacca
    39661 ctaaatcaac atcttcatat cttgatttta tccccttaaa acttttaata ggtcttaaat
    39721 tgacatacaa atctaatgcc tgtcttaaag ttacatttac actcctaaat cctttaccta
    39781 caggagtagt aattgggcct tttatagcta ttttgttctt ttttatacta tctataatat
    39841 attcaggaag tggagtacca tactcttcaa taactgcctc tcctgcatta acttcttccc
    39901 attctatttc tactccagta gcttctacta cctttttcat agctttcgca acttctggtc
    39961 ctattccatc tcctggtata agtgtcactt tatacattca atattccctc ttttcatatt
    40021 aattagcttg atttttagtg tagtttaatt ttccaccagc ttttaataca tcaacttctt
    40081 ttgctgacaa ttctactttg accttaaaag aagttccttt agttgtattc ttaacttcta
    40141 aaattccact acctagattg tctaaaatat ttggtatctc cagattatct aaaagagata
    40201 tattttcata atctttctca tcacaaaact ccattggaat tataccacta tttatcaagt
    40261 tagccttgtg gattcttgca aagctcttaa ctattacccc tttaacacct agatataatg
    40321 gtgctaaagc tgcatgttct ctacttgaac cttgaccata attatctcca ccaactataa
    40381 atccaccatt attgtctttt gctctctgag gaaattctgt atctacagta ttgaaacaat
    40441 agtttgcaag atacggtata ttacttctaa aaggaagtaa cttagcattt gatggcatta
    40501 tatggtcagt agttatatta tcttctgtct ttaatataac ttttccacct atagactgac
    40561 ttagctctgt attaagaggg aaaggtttta tattaggtcc tctaactact tctacatcac
    40621 ttcctacatc agcaggttta attatcatgc tatcatctat caaaaactca tttacatcta
    40681 aatttgtaaa tttaatatca aattctcttg ggtctgtaag cactcccttg attgcactta
    40741 ctgctgccac ttctggactt actaaatata cttgtgctga caaagtccca cttctaccat
    40801 agaaatttct attgaaagtt cttaaagaca cagagtcagt acctggagat tgacccatac
    40861 caatacatgg accacaagaa ttttctagta ttctagctcc agcacttatt atatctgcca
    40921 aagccccatt tctagcaatc atctccataa cttgtcttga acctggtgct attaccaaac
    40981 tcacatcctt atgtacttta tttcctttca ggatttgtgc tactttcatt aagtcttcat
    41041 aagaagaatt tgtacaactt cctattgcca cttggtctat tttaatcttg cctatatttt
    41101 caacttcatc tacattgtct gggctatgag gttttgcagc taatggtttt aattcatcca
    41161 agtttatagt aatctcttca tcataaactg catctgcatc tggttttagc tctatccatg
    41221 cgtcttctct tccttgactc ttaaaaaatt ctagtgtttt ttcatcactt gggaagattg
    41281 aagtagttgc tccaagttca gcccccatat ttgttattgt agctctttgt ggaacagata
    41341 ggcttttgac accttctcca ccatattcat aaactttacc tactccacct tttacagttt
    41401 gttttcttaa cacttctaat attatatctt ttgatgatac catattattt aattttccaa
    41461 ctagattcac cttacagact tttggtgctt ttatatagta tgctcctcct gccatggcta
    41521 aagcaacatc taatccacca gctccaatag ccatcatgcc cacacctcca gcagtaggtg
    41581 tgtggctatc agaacctaaa agtgtatctc ctggtgttga aaatctttct aaaaatactt
    41641 gatgacaaat accatttcct ggcttagaga aataaactcc atatttatct gccactgttt
    41701 gtatatactt atggtcgtct gcattttcaa atccttgttg taacatatta tggtctacaa
    41761 atgccacact tcttttagtc tttactttat ctattcccat agcttctagt tgaagatatg
    41821 tcattgttcc agtagaatct tgtgttaaag tttggtctat ttttatacca attgaacttc
    41881 cagcaacagc ttctccatct actatatgtt ttttaattat tttataaact atattatctc
    41941 ccatattttc ctcctaaaca attatatctt aaatatatga acctctaact gcttcttctt
    42001 ctgttgtgcc tttctcatgt gctagtatat cacaatataa ttgaagaatt tctttatcca
    42061 ttaaacttct ttttaatctt atagatgtag ctcttatagc atttaatagc ttggtagcgt
    42121 tttctggaga aatatacatt tcatattcac tcaacttatt tacaactgca gctcttcctg
    42181 aatgtttacc tattactatt tttctttcaa gatttacttc acttgggtca aatggttcat
    42241 agttatgtgg gtcttttaaa gctccatctg catgtatacc agattcatgt ataaacatat
    42301 tatccccaac tactggtttc catgtaggaa gtattcttcc tgatgcctgt gctacatact
    42361 cacatattcc tctaaatttt ctagtatcta tattatttaa atcacattta taaacacact
    42421 taagtgccat taaaacttct tctaatgctg catttcctgc tctttcacct aatccattta
    42481 ctgtaacacc aacataattt gctcctgctg ctattcctgc aagtgcattt gcagttgcca
    42541 tcccaaagtc attatgtgta tgcatttcta tatcaaaatt agttctttca taaagagttt
    42601 ctattgcatt ctttatagaa aaaggattca taactcctac tgtatcacag tatctaaatc
    42661 tatctgcccc tgcttgtttt ccaacattta taaattcagt taagaagtct atatctgctc
    42721 ttgaagcatc ttctccattt actgaaacat ataatccatt tttctttgca aattcaactg
    42781 ttttagccat attttctaaa acccagcctc tagaagttct caatttattt tctatatgaa
    42841 tgtcagatac tgatattgat atagctactg catcaacacc acaagaaata gattcttcaa
    42901 catcttttat tactgctcta ttccaagcca ttatatctga ttttaaattt ctactacata
    42961 tgtgctttat tacatttttt tcatctccac ccatagtagg tataccaact tcaatttggt
    43021 caacacctag gtcacttaac atttcagcaa tcattatttt ttctctattt gcaaatacaa
    43081 ccccagctgt ttgctctcca tctcttaaag tagtatctac tatttttatt tcctttgctc
    43141 tatcttttga tataacgcac atattaatgc cccccttagt atacttttaa ttttaaaaac
    43201 attaagtctt atttttcatt gatacctcta acttatgatt atttttttat tttttattca
    43261 ttttaatttc atttgcaatt tattttttta gcttttcata tcttgtaatc tattatatta
    43321 ctttgtatca tttattgcac tatatttttt cttttttgtg aaaacttctt aaaaatgaaa
    43381 gttattatgt ttttcttgca ttttaattta atttttaaat agatttattt tcaaaaaacc
    43441 tttaaaaata aacctataaa attcctacta aaatttaatt taagttacat tccattttaa
    43501 agtatcttaa tatattttta agctatataa ataataatta aaaaatttac taaaaatact
    43561 tacaaatatg atattattaa ttggttaata aaaaagaaaa tttttcatga aaggtaagat
    43621 aacaatggat ttcaaaagct tagggattag tgaaaataca ataaatattc taaaaaaatc
    43681 aggaataaca acacctacac ctatacaaaa agaaagcatt aaactaataa aagaaggaaa
    43741 agatgtaata gcagaagctc aaactggaac aggaaaaaca ctagcttttt tacttccgat
    43801 atttgaaaat atatcattag atataaatga tatacaagta cttatacttt ctcctacaag
    43861 agaactagct attcaaataa cagaagaagc tatgaaactt aaagaatcta aagatgtaag
    43921 tattcttgca gcatatggag gaaaagatat tggttctcaa ataaagaaac taaaaggaaa
    43981 tattcatatg attatagcta caccaggtag gcttttagac catctaaata gaaaaacaat
    44041 agaccttagt aagttaaaga cttttgtttt agatgaagca gaccaaatgt tgcttatggg
    44101 atttaaaaat gaagtggaag ctattttaaa agagacttca aacaaaaagc aaacactatg
    44161 cttttctgca actataaatt ctcaagtaaa aaaattagct tatagataca caaaaaatcc
    44221 tgttgtagtt tctattcaaa aagaagaaat cactcttaat aatataaaac aagaggtagt
    44281 agaaactaca gatagaaaaa aattagatgc cttatgtaag gtactagatg aagataatcc
    44341 ttttatggca ataatatttt gtagaactaa gagaagggtt gacaatcttg aagaagctct
    44401 tgctataaga ggatataatt gtcaaaaact tcatagtgat attgctcaat caaaacgaga
    44461 aagaataatg aaatcattta gaaatttaga tatacaatac ttaatagcta cagatgtagc
    44521 ttctcgtggt cttgatatat ctggagtaag tcatatatat aattacgatt taccagaaac
    44581 accagaagac tacatccacc gtattggtag aactggtaga gctggtgaag aaggctatac
    44641 atgtgctttt attgacccta aaaatgaacg aatgttaagt gaaatagaga cggctataga
    44701 atctaaaatt agtagaagaa ttatagaatt ataatttata gattgcttaa aataccaatg
    44761 ccacacaaac actgtaatat atagaaagct acagaaaaca tgtatcaatc tatactttgc
    44821 tgttatacta ttttatatta aagaaaaaag aggctatcca aagtaggatt agtctctttt
    44881 attgtcaaaa taatgaaaat atatttgact tcatataaaa aagagtgcct tataaactaa
    44941 aagtccattt tgagacaccc tctttttatc ttttattctt agttttatat tgcttgttta
    45001 tagttgttta atattagatt ttgcaaataa tcttaataaa catgcagata tattatctat
    45061 agtattctta tctatagtat tctctttagc aatatttttt gctactacat ctaatttaca
    45121 ttttcattta attccgctgg ccatttagct tctggatttt cctttgcaaa cttcttattc
    45181 ttataatgtc ctagtgtaag gaatggaatt actatagtga atagaccaag ataaccacaa
    45241 tatccatatc catatttaac aatattactt aatcctgtaa gtgatataag cattgacact
    45301 accattattg cacaagctgt aaataccctt cttttcattc ttgaagaaag gaaagaaagt
    45361 gctttatggt cttcaaatct atttacaaga ccaaatatag tagttactcc tgtagacatt
    45421 aaacaaagga ataatgcaac attataaatt atgtatatag tatgatttcc agattgacct
    45481 gcaacataaa gagtagggag tgttgtttgc ccagcagcaa taatttctct ataccatccc
    45541 attagcatag ttacagcaag tcctaatgca attgcattca taacaaatga aattatcatt
    45601 gccttagtag cttcttttga gttcttaaga agtggtcttg aacatcctgc aagtgtaggt
    45661 ataacaaccg attgaaaacc tgcataaata aaagtattaa gtattggctt gatatagcca
    45721 ggtgtgaaac tcgttctatt tgataatatt tcagttattt ctggtacttt agcttttata
    45781 ccaacaataa aaatagtaag agtacatact agaatagcta ttgtcattgc tgtagctgct
    45841 ttagatacaa gcatagcacc aaatatagta aagacaagaa gtacaactcc aataataaat
    45901 acagctacaa aataatttac tcctatactt tgaaatactg ctgctgcacc tgctataaca
    45961 gcacttacag ctattaaaac cattagatag taatatatct cccatattat ttcaagtttt
    46021 ggatatggtc tccaaagctc acaaaataaa tccttataat tcctacaatt gttattatta
    46081 tacattatga taacttctct catggtagca gtaagtataa tcattgctaa aattgccata
    46141 agtggtgctg tccatccata ctgcacatag tactgagttt cttgattccc tgtagcaaat
    46201 cctcctcctg catgtgaact aaaaagaacg cttgcaacac caaaaatggc taacatagag
    46261 cccgttactt ttgctttctt tacacttttt tgcatgaaat catcctccct aaaatgatat
    46321 taaaagtttt tattttaaca ctttattgat aaaacaataa catttttgct cattaaattc
    46381 aactatattt ttccaatgac tttacatttt c
//
LOCUS       DAEPUT010000025        45475 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.025, whole genome shotgun sequence.
ACCESSION   DAEPUT010000025 DAEPUT010000000
VERSION     DAEPUT010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45475
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.025"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            415..1251
                     /locus_tag="KRL22_001540"
     CDS             415..1251
                     /locus_tag="KRL22_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1272038.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1604..3181
                     /locus_tag="KRL22_001541"
     CDS             1604..3181
                     /locus_tag="KRL22_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1272039.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPVEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            3174..4358
                     /locus_tag="KRL22_001542"
     CDS             3174..4358
                     /locus_tag="KRL22_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBH1272040.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLKHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEESEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     IL"
     gene            4376..4975
                     /locus_tag="KRL22_001543"
     CDS             4376..4975
                     /locus_tag="KRL22_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1272041.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFIHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4999..5469
                     /locus_tag="KRL22_001544"
     CDS             4999..5469
                     /locus_tag="KRL22_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1272042.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIIVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEVLVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5828..6574
                     /locus_tag="KRL22_001545"
     CDS             5828..6574
                     /locus_tag="KRL22_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBH1272043.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHVELEHSDYLEQLINSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKFYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6635..7309
                     /locus_tag="KRL22_001546"
     CDS             6635..7309
                     /locus_tag="KRL22_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBH1272044.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTHGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            7678..9024
                     /locus_tag="KRL22_001547"
     CDS             7678..9024
                     /locus_tag="KRL22_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH1272045.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQNIVSDKSLGGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGGNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIITLTGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDITVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMYYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLESDSLNEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            9051..10451
                     /locus_tag="KRL22_001548"
     CDS             9051..10451
                     /locus_tag="KRL22_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH1272046.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKNICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAVICEDKQ
                     GEPGHYENLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNEDNWEDFKEDKH
                     KVYLIEALKTKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSNDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            10661..12097
                     /locus_tag="KRL22_001549"
     CDS             10661..12097
                     /locus_tag="KRL22_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH1272047.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNIGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIVSNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGEETVYYYKHHEPDKTNQIQ"
     gene            12441..13385
                     /locus_tag="KRL22_001550"
     CDS             12441..13385
                     /locus_tag="KRL22_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HBH1272048.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLEEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLRDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEIFKIAHKHGITLEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEGNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            13554..14486
                     /locus_tag="KRL22_001551"
     CDS             13554..14486
                     /locus_tag="KRL22_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBH1272049.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14591..15058
                     /locus_tag="KRL22_001552"
     CDS             14591..15058
                     /locus_tag="KRL22_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HBH1272050.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15302..16156)
                     /locus_tag="KRL22_001553"
     CDS             complement(15302..16156)
                     /locus_tag="KRL22_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBH1272051.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            16322..18286
                     /locus_tag="KRL22_001554"
     CDS             16322..18286
                     /locus_tag="KRL22_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1272052.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            18286..18747
                     /locus_tag="KRL22_001555"
     CDS             18286..18747
                     /locus_tag="KRL22_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1272053.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18750..19070
                     /locus_tag="KRL22_001556"
     CDS             18750..19070
                     /locus_tag="KRL22_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH1272054.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            19086..20186
                     /locus_tag="KRL22_001557"
     CDS             19086..20186
                     /locus_tag="KRL22_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH1272055.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20306..22906
                     /locus_tag="KRL22_001558"
     CDS             20306..22906
                     /locus_tag="KRL22_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBH1272056.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGIKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INIQLPAIGYKVVSFELSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
     gene            23375..23710
                     /locus_tag="KRL22_001559"
     CDS             23375..23710
                     /locus_tag="KRL22_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272057.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            23847..25124
                     /locus_tag="KRL22_001560"
     CDS             23847..25124
                     /locus_tag="KRL22_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HBH1272058.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIRSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            25245..26633
                     /locus_tag="KRL22_001561"
     CDS             25245..26633
                     /locus_tag="KRL22_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1272059.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRTLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            27004..27717
                     /locus_tag="KRL22_001562"
     CDS             27004..27717
                     /locus_tag="KRL22_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HBH1272060.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            27835..28704
                     /locus_tag="KRL22_001563"
     CDS             27835..28704
                     /locus_tag="KRL22_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1272061.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(28859..30004)
                     /locus_tag="KRL22_001564"
     CDS             complement(28859..30004)
                     /locus_tag="KRL22_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH1272062.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDIDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(30337..31113)
                     /locus_tag="KRL22_001565"
     CDS             complement(30337..31113)
                     /locus_tag="KRL22_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH1272063.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            31695..32669
                     /locus_tag="KRL22_001566"
     CDS             31695..32669
                     /locus_tag="KRL22_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH1272064.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            32767..33072
                     /locus_tag="KRL22_001567"
     CDS             32767..33072
                     /locus_tag="KRL22_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1272065.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            33228..34388
                     /locus_tag="KRL22_001568"
     CDS             33228..34388
                     /locus_tag="KRL22_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1272066.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLIKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            34438..35340
                     /locus_tag="KRL22_001569"
     CDS             34438..35340
                     /locus_tag="KRL22_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH1272067.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            35420..36313
                     /locus_tag="KRL22_001570"
     CDS             35420..36313
                     /locus_tag="KRL22_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBH1272068.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      36366..36547
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            36775..37905
                     /locus_tag="KRL22_001571"
     CDS             36775..37905
                     /locus_tag="KRL22_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1272069.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            37977..39002
                     /locus_tag="KRL22_001572"
     CDS             37977..39002
                     /locus_tag="KRL22_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH1272070.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            39005..40201
                     /locus_tag="KRL22_001573"
     CDS             39005..40201
                     /locus_tag="KRL22_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272071.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(40329..41054)
                     /locus_tag="KRL22_001574"
     CDS             complement(40329..41054)
                     /locus_tag="KRL22_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH1272072.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRRY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            41532..43631
                     /gene="nrdE"
                     /locus_tag="KRL22_001575"
     CDS             41532..43631
                     /gene="nrdE"
                     /locus_tag="KRL22_001575"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBH1272073.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            43644..44615
                     /gene="nrdF"
                     /locus_tag="KRL22_001576"
     CDS             43644..44615
                     /gene="nrdF"
                     /locus_tag="KRL22_001576"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBH1272074.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            44691..45317
                     /locus_tag="KRL22_001577"
     CDS             44691..45317
                     /locus_tag="KRL22_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH1272075.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT        17781 a         4809 c         7974 g        14911 t
ORIGIN      
        1 taattttata aaaaaaatta taaaaaattt taatttaatt tatataaatt aaaaattata
       61 ttaccaatgt atatatttga gaaaagatta gtacaaagct ataatctgaa tttcaataaa
      121 tatatatata attaagttga aatacttgaa aatactggaa aaaattgaaa ataatttttg
      181 taatataaaa tgtcgattga ttttaaataa ttaaatatac ataagaaata attaaatata
      241 tttcaatgaa aatatgacaa attaattgat gacaataaaa aatattttgt tattgtagta
      301 ttatagggta aattgcaaaa tatatacgaa agtaaaattt taaatattga cattaaatta
      361 aatatactat actatgtaag tgtgatgaga gaattttttt agaggggatt tatagtgaat
      421 ataaaaaaga tatttaataa caatgtagta gtaagctccc tagaagatgg cacagaaata
      481 attgtcactg gtgctggagt aggatttaag aaaaaagtag gcgatttgat agatgaaaat
      541 ttgatttcta agaaatattt tgttcaagac gatcaaaggg acaaatacaa tcaaatactt
      601 aataagacct ctattgaata ctttaaaatt tcagaagaaa ttatagaaaa ggctaatgaa
      661 gttttaaata ctcaagtgaa tgattcaata atattagcct taactagtca catagaattt
      721 gctgtccaaa gagaaaaaca aggtataaaa ttaccaaact taatattgaa tgagacaaaa
      781 caactttata gggaagaatt tgaatttgga ttatgggcaa ttgatgaaat tgaaaaaagg
      841 ataggaataa aattgcctga agatgaagca ggatatattg ctattcacat aatcaatggt
      901 ttggaaaatt ctcaaaaaga tgaaggtatt aatatactag agttttcaaa acaagttatt
      961 cagataattg aagaagtaca tggatttaaa ttggatgtaa attcattaaa ttatactaga
     1021 cttataactc acttaaagtt ttttgttcaa aggattctcc gaaaagaaac ttacaatgat
     1081 agtgatattg aagatatgta taagttagtg aataaaaatt acaataaacc taaagtgtgt
     1141 actgaagaaa ttgcagcatt ggtattagac agatttgaat ataagattag taaagaagaa
     1201 gaattatatt taatgattca cataaataaa ataacaaaca gtggttgtta ggattgtaac
     1261 tgataaagca ggcaaaacct aagtcattga gcttaactat tagattaagt tttttgattt
     1321 aggttttttt attagataca atcaaaatac agacagtgac ttttaggatt gtaactggtt
     1381 aagcaggcaa aacctaaatc tttgaattta actattaggt taagtttttt gatttaggtt
     1441 tttttattag atacaatcaa atacagacag tgacttttag gattgtaact ggttgagtag
     1501 gcaaaaccta aatcattaaa cttaattatt aaattaagtt ttttgattta ggtttttcta
     1561 taaatttgat tatgttttta gataaaaata ggaggggaaa attatgaaaa aaaataagtt
     1621 aggtttatgg aacttcttcc aaatgttagg aaaaacgttt atgttcccaa tagcactact
     1681 tagtgtttct gggatgatgc taggacttgg ggcaggtttt acagacccta agatgattga
     1741 aatggttcca tttttaggga atgaatatgt taacttagtt ttaaacttca tgttaacaat
     1801 aggattattt gcatttaaca acttgggagc attatttgca atggcaattc cactaggatt
     1861 attaaaaaaa gaaaaagagt ttggtgcttt ttcaggatta gtaggattta tagcaatgca
     1921 cataggtaca aatttttatt taacaagagc tgatttgtta gtaccagtag aacagatgtc
     1981 aactaatggt caagctatga ttatgggtat acaaacatat aatacaagtg ttttaggtgg
     2041 tattgtagca ggattaattg tttatgcaat atatgataaa gttagtaatt taaagatacc
     2101 agaatcatta ggattctaca gtggaccaag attagttcca attgttagtt taatagttat
     2161 gagtatagtt ggattattaa tacctattgt ttggccacca tttttcaatg cattccaaag
     2221 tttaggaaga tggatttctt cagcaggacc attaggatat ttttcatatg cagtggcaga
     2281 aagagttaca attccatttg gactaaatca tcttgtaaca tccgtattcc gttttacacc
     2341 aataggtgga actgctgtta ttgatggaga aacgtacttt ggtacattga acatgtttat
     2401 ggcatatgta gaaaataatc agattatacc tcttgattta gctggtaaaa tggaacaagg
     2461 taaattgatg attcaatatg gattagctgg tgctgcattg gctatctacc gtacagcaaa
     2521 accagaaaat agaaaggcac ttaaaggact tttaatatca ggagtgttga cagttattat
     2581 aggtggtata agtgaaccaa tagagtttct attcttattc atatcaccag cattatttgc
     2641 tttccataca tttatgaatg gtctagcaaa catggtactt ccatacttag gcgtgttgat
     2701 gggattcaca ggagatttaa ttgcatttat aagttttggt gtgttaagag gaacagctac
     2761 aggatggcca atagcagtat tagtagcagt tttatatttt gcaatatact attttgtatt
     2821 taagtgggca attattaagt ttaatataaa gaccccagga cgtgaggata aagaaataaa
     2881 agtatctgaa ggaaatggtt cagatttcaa aaatttgtct acatataaag gacaacaaat
     2941 gatatctgct ttaggtggtc aatctaatat attatcacta gataattgtg taactagatt
     3001 acgtttaaaa ttacaagatg tatcattaat aaatgaggat gcaattaaag aggctggtgg
     3061 tatagcagtt gttaaattgg atgagcatac aatacaagta attataggaa ctcaagtgta
     3121 ttctttaaga aagcagatgg ataaagctat ggaaggtcat ttggaggcat gtaatgatta
     3181 attttgataa aaaagtagac cgattgggta catattgtac ccagtgggac tatgtagaag
     3241 atagatttgg taagaaggat ttgcttcctt ttacaatttc agatatggat ttagagtttc
     3301 catttgaaat aacagaggtg ttgcaggaaa ggttaaagca tagagttttg ggatacagta
     3361 gatggaaaca tgatgatttt agaaattcag ttacgaattg gtatattaaa agatttaatt
     3421 gtagcgttga tagtaactgg atatattata gtccaagtgt aatgtattca attagcaaac
     3481 ttattgagat gttaagtaat gaaggagatg gaatccttat aaatactcct gcatacaatg
     3541 ctttttatga tgtgataata aataacaatc gtaatattat aaagtcacat cttgtaaata
     3601 ggaatggatt ctattcaatt gattttaatg attttgagaa aaagtgtaaa aaatctaaga
     3661 tatttatttt atgtaatcct cacaatccaa ctggtagagt atggagtgag ttagaacttg
     3721 ttaagatgat agggatttgt aagaataatg atgtcaagat aatatcagat gatatacaca
     3781 tggatattgt atatgacaat agaatgacac ctatcttaaa tgttgcaaag gactatttag
     3841 attctgtatt catttgtaca tcagcgtcta aatctttcaa tataccagca ttgactgggt
     3901 catatgtgat tataccaaat gaaggtatta gaaataaatt tgaaaatatc actagatacc
     3961 gtgattttgt aaattctcca gcaattctag caatattagc tacaatggtc tgttatgatg
     4021 actgcgaata ttggttagat gaactattaa aataccttaa agagaatctt aaatatacga
     4081 ttgattatat aaaagataat ttagaaccat tgaaattggt catgccagaa ggctgttact
     4141 ttgcttggat agatttttcc gaacttaaaa taagtggtga gaaattccaa aaattattga
     4201 tggatattgg agaagttgct attatgtcgg ggtctgtata tggtgaagaa agtgagtttt
     4261 atttaaggtt aaatgtggca tgttcaagag aaaaacttga agatggttta aataggatta
     4321 aaaaaactat ggattatatt gcaaaaagaa ttttatagta ggaagggaga tagttatggg
     4381 atatttaaaa acaatggttg atgttatgac tactgaaatg aatgccataa gatgtttaat
     4441 agatgaagca ggaatagaat atgaaagtat agttagtgaa attgcaaatt gtgaaggcaa
     4501 agtaattttt atgggtgtag gaaaatctgc acatataggt aagaaattgg cagctacatt
     4561 tgctagtact ggtacaccta gcttttttat acatgcaaca gaggcagtgc atggagattt
     4621 aggaatgatt gaaagtaagg atattacaat tttaatatca aatagtggaa attctatgga
     4681 agtggtaaac tgtataaaat atattaaagc aataggttct aagacaattg catttacttc
     4741 aaacagaaat tcagtactgg caaaagagtg tgattatgct ttaatatatc ctgcaaagga
     4801 tgaagcagac catttaaatc tagcaccaac aacatcatct acaattactt tggttttagg
     4861 agattctatt gcatgtgcat tatctaagag tagtaatttt ggttcttcag atttttataa
     4921 gtaccatcca ggaggaagtt taggtgagaa gttaaaaaca gctaacaatg gataaaagca
     4981 aaaaggagag tagtttttat gttcaaaatg tttaaaaaaa aatcaataaa atcacccata
     5041 tcaggaaaag taatagagtt atctaaaata caagatggtg tattttctca aaaaattatg
     5101 ggagagggtg tagctataga ttctacagga gacattgtat atgctccaat caatggaaag
     5161 ataatagtag tagcagagac taaacatgca tttgtaatag aattagaaaa tgggatggaa
     5221 cttcttattc atgttggttt agatactgta aatttaaaag gcgaaggttt tgaggtattg
     5281 gtgagtatgg gagaacaagt gaaggaagga acaccaatgt tgaaaattaa ccgtcctttg
     5341 attgaatcaa agggtatatc acttattact ccagttacaa taactaatca ttcagagtac
     5401 aatatgaata catgtaatgt aggcaatagt gttgaaggtg ggaaagatac tgtaattgag
     5461 tttaaataaa gaactaaaat acaaggttaa tatttataaa tacctataaa cttatgtttt
     5521 ataagattga ttgtatagat ttgttgtata aaaaagaact ctttaattat aaattaagga
     5581 gttctttttt attttgtaaa tattgtttag atttatatag aaaaacactt agtaataaat
     5641 agaataaata agtatttata tagctaaaaa tctaaatagt tttgtttaaa tatattttta
     5701 tattttgtaa tttcaaatta ataaataatt agatttgata aacaaaaaat aaaaatgttg
     5761 attacattaa taaactttaa tataatatat ttatgaaaaa tgtaaactgt gaaatggagg
     5821 tagtaacatg aaaattgaaa atctttctat tgatgatatt aaacgaggct atatatttaa
     5881 tgatgattta aattgttata gttgcattaa atgtacaaaa acatatgagg taggagaaat
     5941 atataaaata ggtaatagat tctttgaagc ttcaaaagct attgaacttc atgtggaatt
     6001 agaacatagt gattatttag agcaattgat taatagtgat tcaaaataca acacattgac
     6061 tgaaaatcaa aaacaattat ttcaattatt tattagtgat ttaccagata aggagatagc
     6121 aaaacaggtt ggagtatcca catctactat acgccatcaa aaatttattt tcagagaaaa
     6181 agcaaaacag gctaagttct atttagcact atatgaatct gtatttgaag ataaatctaa
     6241 taaaagtagt actataatac caatccatga acatgctcga atggtagatg aaagatatgt
     6301 agtaactgaa gaagagagaa aacacatttt ggatacatca tttgaaagta tgaatccttt
     6361 aaaattaaaa gtattttctt caaaagaaaa gaaaaaggtc gtaattttat ctaagatttt
     6421 ggaacaattt gaacgtggga agaaatattc agaaaaggaa gttaatcaga ttttagaatc
     6481 tatatatgat gattttgcaa caattagaag atatctaatt gagtatggtt ttatgagtag
     6541 aaataaagaa tgtacaaagt attggttaac ataattaaaa taataaattt tactaatgtg
     6601 taatgttatt tttatctagg gggaggagtc aaatatgaat gatgaattaa aatctatttt
     6661 atacaataaa ggtgtggaca ttgttcgctt tgttgatata tctgaatttc caataaatca
     6721 aacgcacggt ttttctaaag caattttatt ttgtataggg ttatcaaaaa aatttattac
     6781 agatatatac aataacttac ctacagatag tgatgagttt ttggaaaaag aggagaaagt
     6841 agaagaatta gctgactgga tttcaaaata tattcaaaat aaaggatata gagcgtattc
     6901 tcaatcggag aaaaacaatc tagaacatgg atattttgaa aaagcctata ttaatccaga
     6961 aatgcaatca gggattagtc ctttaccaca taagacaata gcaaatatta gtggcattgg
     7021 atttatggga aaaaataatt tgtttgtaac agaggaatat ggatgtgctt ttagcatgtg
     7081 tacagtactt acagatgctc caatttctgt tgaaagatat cctttgattg attcaaaatg
     7141 tatggattgt aatgtttgtg tagaaaactg ccctgcaaaa gctatacatg gaaatgagtg
     7201 gactttgcca ggaaaaagag agtctattat tgatgtttca aagtgttttt gtgtattgag
     7261 gtgtatgatg agttgcccat ggtcattaag atatgcaaat caaaaataac tttactagag
     7321 aaggtattaa attgaatatt ataaaatttt taaaatgtaa gattatataa gatttctcaa
     7381 aataaaaatt tgtatagaac actcagaaat gagtgttttt ttattggaat taaattatat
     7441 tgatacaaag cttaactatt ttaatcatta tataaaattt gtattaaaaa attaagaata
     7501 acttggtaat agtgaaaata taatgagatt ataattgatt tataatataa ctataatgat
     7561 attgtaaaaa tgaaaattgt cctctcaaaa ttcccaaaga gagtaaaagt cacttcagtt
     7621 atagtcaaaa aaatttttct gtgaaaagaa tttagatttg aaaaggagga attaatcatg
     7681 gaaattgaaa ctaaaactcc agattggatt aatgtactag aattaaacag taaaatagat
     7741 attactggga aatatgatgt aagtaatatg atacaaaata ttgtctctga taagtcacta
     7801 ggaggttcca ttatatattt tccaaaaggt aattacttat ttgagaaagg tattaaaatt
     7861 agtcaacaaa taacacttca aggagattct tattatggag gaggtaatca agtatcaaat
     7921 ttagataaaa aacaatcaat cataggaaca accaatttta taacccgagg agtttctaat
     7981 atgagtatta ttacattgac aggaacaagt caatgtatca aaaatattaa tttttattat
     8041 gatagtcatg atatagagaa aataccgcct aaaaatgtat ctgctattac agaatatgga
     8101 gaaacacaag gattatctca ttttgaacat ctgtttattt ctggattttc agggatagga
     8161 attgaaattc catactattc aactggtaat gatattactg ttagttcatg tggtcttggt
     8221 atgaggcttg gagagaagtc aatgctttct agtagcaaga tttacgaatg taaaaatgga
     8281 atggagatta ctactggtgt tagcttaaat aatgtgagaa tagaagaaat aaaagaaata
     8341 ggtattaata ataaaggatt tggttttaat ctgattatga atcttatggt cgaccaatgt
     8401 ggatattgtg gatttatgtt tgaaaaaatg tactatagtc agataactgc cagaattact
     8461 agatgcggtc agtattataa aagtgttgat tataatgctt atgagaatat ggaagataga
     8521 aaagaagaag cttattctat tttttatgga gatattttag aaaattgcaa tattgtattg
     8581 atgaatagca atattgatac cttagaaagt gattcactta atgaacataa gatatatgta
     8641 atcaaggcaa atgaaacaaa caatgtaatg ctaacatgtt atgctgaagc agataacttt
     8701 atacaatgtg caaagggcaa cttgctgtta gaaaatggtg aaaatactta taaattttat
     8761 aatggtgaga tttgttctgt aggaggtgtt caaatttctg atatagatga aaaagattta
     8821 atcaaaataa tagagaacac tttgtatata gatgataaag gtaagtattt aatggttcct
     8881 agattaaaaa agaatactgt aatatattca gtactagatt ctacagaaga aataaataaa
     8941 ttacatggtg gaatatggga acagattgat gtaaaagtat tagctgggga atccatgtac
     9001 tattataaaa agataaaaga ttaaattatc aaactaggag gtagtgatta atggaagagt
     9061 ctataataat taaagatata agtggctgga ttaatgtact tgattatgga atttgtaatg
     9121 atgaaacaaa agatgtaagt tttaagttgc aagagattat ggatgctgta ccagaagatt
     9181 ctattatata ttttccaaaa ggaaaatact tatttgaaag tggtgttaag attaagaaac
     9241 gattaacctt atgtggagat tcttatattt tagcgaatgt tcctaaaaat actgctggag
     9301 taacacagtt tacttttaaa ggaaagaaaa atcctaaaag tgaaaatata gcaatcataa
     9361 cagcaaaaag tgtaagacac tgtattaaga acatttgctt ttattcagat agttgtgata
     9421 gagatatgac atctaatcat gaacctccaa cagatggaaa acctagattt catcataatg
     9481 taattataaa ttatagaaat atatctgctg ttatatgtga agataaacag ggagaaccag
     9541 gtcattatga aaatctatct tttagtggtt tttctggaat tgcacttgat atgcctaata
     9601 attctacagc aaatgatatt acaattttta catccggact tggaattagt acaggggaaa
     9661 attcaacaat tgctaacagt aaggtttggg gctgtgttga tggaatgata atttctactg
     9721 gaacttttat aaatggtatg agggtagaag aaataaaaaa agttggaatt aaaaatattg
     9781 gtagaggttt aaattttatt acaaatatca caattgacca atgtggatat tgtggagttt
     9841 ggtttgattc tatatccaat gttcagatat caggaaatat cacaaggtgt gggcagtact
     9901 attatgatgt aagctatgat aattatttaa tgttggataa tagagttaaa gaagcatatt
     9961 ctttattcta tggtaattta ttggagtcaa gtaatatagt tttatcaaat accaatgaag
    10021 ataattggga agatttcaaa gaagataagc ataaggtgta tcttatagaa gcacttaaaa
    10081 ccaagaatgt actattaaca tgcaatatag atgctactga ctggattgtt aagtcagaaa
    10141 aaggaaattt aacgtacaat aatatgcgac aaactgttat attttacgat ggaaaactaa
    10201 gtagtatcaa tggaattggt atatctgatg aagattatgg ggataaagtc aagataaaaa
    10261 aaggaaatat atatataaat agtaatgata aggatattaa gatgcataaa ccagaggtag
    10321 gtgacattat gtcaacaatt attaaagata aaagtattct ttctgctcat tatgggggaa
    10381 catgggagaa aattggtgaa aaaatagagt ttggaataac tgtacactat tataaattga
    10441 tagagaaata agtaaatacg tagtatttga atagatgtat tttattggag agctaggact
    10501 atagttttaa tataaatggt ttggtaatag catggattga ataatataaa aataatataa
    10561 aaaattaatt tgattatgta aatttctatg aagtagtaaa actgtgactt tagtcatagg
    10621 aggttcaaac taagtaaaag ggaaaggaat atataatatt atggaaggaa gaactgggat
    10681 taaagatgga agatggatta atgtagtaga aagaggtatt aaaaatgatg gttcgtacaa
    10741 cataggtcct gctttgcagg atattattga tgaaatagaa acagattttt gtgtcttata
    10801 ttttccaaaa ggtaaatacc tatttacaag tggtgttaaa attaataaag aaattgtatt
    10861 gcaaggtgat tctaattcat ctacaggtac tacacaattt ataactcgtg gagtagaaaa
    10921 tatgagtatt attacattga cagggaagaa acaatgtatt aaaaatataa atttctattc
    10981 tgatagttgt gagatacagg taaataaaga accaccgaca aaaggtaatc ctaaatatca
    11041 ttatgagatg attattaata agaatgaaaa gaatgttgag atgaataatg tatcagcaat
    11101 cctgtatgat aacagtaaga atatgattaa aggtctaggt cattatgaaa atatttatat
    11161 aagtggtttt tcgggtacag gaattaggat accatattac tcaattgtaa atgatattac
    11221 agtttcatct tgtgggctgg gtattgatac aggaatagac acaattgttt ctaatagtag
    11281 aatatctaag tgtcaaaatg gaatgaggat taggactgga actagtataa ataatgtaag
    11341 gattgaaaaa atacagaaag ttggtcttat aagtagtcaa gttaaggggt atgaggggta
    11401 tggaagttat aaaattaata atattacgat tgaccaatgt gggtattgtg gcttttcatt
    11461 tgattcaatg aaagatagtt atttttctgg tattataaga aggtgtggtc agtattatta
    11521 taatacagat tatgacacat atttaagtat taaagataga gtagaagaag catattcttt
    11581 attttatgga aattatttta cagaatgtaa tattgattta gttagtgata ataaggataa
    11641 ctgggatgat ggcttagaat ataaacataa agtttatgta tttaaaaccc ttcaaatacc
    11701 aaaattaaca ttgagatgca atatagatgc ctatgattat atcgttaaat cggtacatgg
    11761 aggaggtaat ttaatgttaa aaaataactt taacaattat atatttattg attcatctaa
    11821 tccagaagtt attaatggaa ttaattttaa ttatcaaaag aatggaaact tgttaaggtt
    11881 aaataatggt aaattaagtt ataaaaatgg aaaggaagaa acagctatat tcagacctaa
    11941 ttatggtctt attgtagcat caacagattc agaatgtgaa caaatagaga ctagctatgg
    12001 aggaaaatgg gagaagcttg gttctgaagt aattggagaa gaaacggtat attattataa
    12061 acatcatgaa ccagataaaa caaaccaaat acaataaaat ttgtattata taatgatata
    12121 aagttttaat atatagtgtt tacctttaat gtaatattgg tatatttgta tagtattaaa
    12181 tttgttaaaa agtaaaattg tagggtgctt gaaaatagca ccttttttag tttcattata
    12241 aaattagttt tgaaagttta ggaataatgt atatttattt ttaaagaatt ataaccttat
    12301 taaggatatt ttaaatgcta gaaatgaatc agtaaatcat actggaatta tcttaaatgt
    12361 tttgattaaa ttaagtattt agagctataa ttatattaaa aatatattag aacataatta
    12421 tattactatg gaggttaaat atgatagtaa gtgtgagtag aagaactgat atacctgctt
    12481 tctatagtaa gtggtttttt aacagacttg aagaaggttt tgtttatgta attaatccaa
    12541 tgaatccaaa acaggttagt aagatagagt taaatccaca tactgttgat tgttttgtat
    12601 tttggacaaa ggatgtaact ccaatgttat atgatttaaa taaattaaga gactataaat
    12661 attattttca ctatactata acatcatatg gaaaagaagt agagacatgt attttagata
    12721 aaagaaaggt aatagattca tttaaggaat tgtctagaaa aataggcaaa gaaagagtaa
    12781 ttttaagata cgacccgatt ttcttaagtg aaaagtacac agtagattat catatcaaag
    12841 catttgcgag tttatgtaat cagcttgatg gatttacaga aaaatgtata ataagtttta
    12901 tcgatttata caagaaaaca aaatttaata ctaaagcatt acatataaag ccaatagaaa
    12961 ttacagaaat agaaacatta tcaaaagaga tttttaagat tgctcataag catgggataa
    13021 cacttgaaat gtgttctgaa gaatataatt taagtaaatt tgggattgga aaaagtaagt
    13081 gtattgatga tagattaata tcaaaaatta taggatgtga agtagaggta aaaaaagata
    13141 gtacacaaag agatatttgt ggatgtgtta aaagtgtcga tataggacaa tacaatactt
    13201 gcagacatta ttgtctgtat tgttatgcta actttaatta tgcaaaagta gaagaaaact
    13261 gtaggcttta taaagaaggt aataaattac tcatagatac tttaagagat gatgcaaaaa
    13321 taagcattag agatatgaag actattaaag tagataagaa taaacaaatt agtatatttg
    13381 attaaaataa atatactaat taccttaata tattaagaat atagatactt ttgataacaa
    13441 aattaaactt aatagatatt ttctatataa gaaagatggt cataatatgt caatttgacc
    13501 atatttttga tataattaaa acacaaataa tttagtaaca aaggaggcag aacttgaatt
    13561 tattaaaaaa atatcctata cctattgcaa gtttgatttt gtcaatcttt actttaggta
    13621 acttattaca atcttatagt gaatcattac gtaatgtaat tggatttata ggatttattt
    13681 tgtatgcaat ttatatagtc aaaataatat tacttagaaa gggtgttaaa gagcaattag
    13741 agaacccttt aatatcaagt acatttccaa ctataacaat ggcaacaatg atatttgcta
    13801 catatataaa accattatct ttagaattaa gtattatgat ttggagcata ggaattgtgg
    13861 gtcatcttgt gttaatagtc ttatttagta agaagttctt agttaaattc tcaataaaaa
    13921 cggtatttcc atcttggtat atagtatatg ttgggatagt tgcagctagt gttacggcac
    13981 cagcatttaa tcaacttttg attggcaaaa ttgccttttg gataggattt gtatcttata
    14041 tagttcttat accagtaatt ttaaagagag tatggataat caaggaaatg cctgaaccat
    14101 ctttaccaag tatagctata ttagctgcac cagggtcact attattgtct ggatatatta
    14161 attctttttc agataaaaat aatgtagtat tatacttgtt attcatatta tcaattgtat
    14221 tttatattat agttttggga tatttaccga aattattaag attgcctttt tatccgagtt
    14281 ttgctgcatt tacatttcct atggcaataa gtgcaatggg tatgaaacta atgaatggtt
    14341 atttaactaa atcaggtcat tttataagtt ggatttcata tgcttctaag ttagaagaga
    14401 taattgctac agtgattatt ttatatgttt tagttttgtt tattatatat cttagtaaat
    14461 ctgaaactac atctaaagct aaataagaat tattaaatat gtgtatttaa taggaatatt
    14521 gatataaata tatgaagata agataaacca tagaaactta atttagctta attttattgg
    14581 aggaaaacaa atgaaaacaa aagaagaata tttaaaagaa gttagaaaca tatcagaaga
    14641 atactttaga aaaggagagt ttttttgctc tgaagcagtt ctccagacaa taaatgatgc
    14701 tttaggccaa cctttaagtc cagagataac taagttagca tcaggatttc cgataggact
    14761 tggaaaggca caatgtcttt gtggagcaat atctggggga gagatggctt taggtatagt
    14821 atatggaaga gttcatggtg aagctatgaa tccaaagatg tttgagcatg ctaaaggttt
    14881 gcatgattat attaaaaaag agtatggtgc aacatgttgt agagctatta caaagaaatg
    14941 ggatggtgat aactttatgt ctcccgaaag aaaagagcac tgtattaaaa taacaggtca
    15001 agttacagag tgggttgcag ataagcttat agaagatgaa aaacttaata tcaaatagtg
    15061 taatattagt tggtgaattt ataaagttaa atttacttat agtataagat acttgatatt
    15121 ctcgtattga tagaaaaatt tatagcatat gtatttaatg aaatatactt atatttagag
    15181 tgtggtttaa tttcataaat acatatgcta ttattttaag tatataagca aatttattta
    15241 aataaataga aacagttaat ttatatgtac aaaactatat atgattagtg taaataaata
    15301 cctattttat aatactcaac ataaagacac cagacatgat tagtattata ccaataaaaa
    15361 tagcaagcca ttcttttttg ttcttctttt ctttaaaaaa tataatccct cctaaagtgg
    15421 ctactatcac acaactctga gagatagaaa aacttattgt aactcccaat gtattagtcg
    15481 ttatgaacat acctaaattt gctattgacc acaatatacc agtaattaaa ttgaataaaa
    15541 cattttccct atatacaatc tctttagaaa aatacttgac aataatagat gaagttatca
    15601 acataccaac agattgaggt aatataattc tatatccttc aattaaaaat atttgattag
    15661 ttacaacata taatgataaa aatagagatg ataataatac aactccaaca cattttaaca
    15721 tatttttatc tgtagatttt ttagtttgat aatttgtgag aagtatacca agtattatac
    15781 ataatattga taaagaacca atcagtaaca ttttagaact ggtccattca ttaaacaaga
    15841 ttacagctaa taatgtcgta aaagttaatt gtgaaccatt tgaaattggc attactttag
    15901 atacactagc aatttgaatt gctttaaact gcattaattg tcccaaactc cagaatatgc
    15961 cagaaatcat acttatacaa aatgaaaaaa atgtaatttc aggatgtata accagagtta
    16021 ttatagtgga aaatataaac gcacttatgg atgtacctaa aagctgttca tgaggagaac
    16081 ttttctttag atttgcaact atgggcatca atccccatcc cattacagga agtaaagcaa
    16141 taattattgt cagcattaaa ctatttcctt tcatattaaa tttagacagc ttttaattta
    16201 tcatctaaaa ttaaagtgtt caatacataa aaattaccgt atttaatcag gaaatattag
    16261 tagtttttta gaaaaacatt ttccattaaa ataaagacaa agggaaggag taaaattgaa
    16321 aatgttaact gatatgattc aaaatcgtga aattaaaata ataaagtttt tattaaaaga
    16381 aggtcataca actgtaaaag caatagcaga tgatttagat gtttcagaaa aaacagtttc
    16441 aaaatctctt aaagaagtag aagcagtgct taaaaagata ggtctttctt taataagaaa
    16501 acctaagata ggtgtttata ttgatggaga tttaaaaaaa atacttcctt acctagataa
    16561 taaaggaagt caaattccta caaccagaga ggagagagtt atctatatat attcagtact
    16621 tttaaagagt aatgattata ttactataca acaactttct gatgaactat atataagtcg
    16681 tggaactatt gaaagggatt tagcagaagt tgaaaaactg ctaaaaaacg aagggatttc
    16741 catatataag aaacctagta agggaataaa gttaaatata agtgaaagag ataaaagaca
    16801 acttactgct aagtttatac ataaattttg gagtagaaac tggtatatta agcaagagca
    16861 agaaagcttt tatcaagcat ttgaaaagat acaagcagat gtaaatggta ttttttcgga
    16921 agatgattta tcaataatta ttgatattct taggaatttc agcagagaaa gaaaatttga
    16981 gttctctgat tatgaatttc agtcattagt tattcatttg gcaatagctg tagagagaat
    17041 tagaaaaggc gaatatatag aagaaagttt gtatactggt aatatagaaa ataatcaaat
    17101 gtcaaatacc aattatttag caaaacaatt agaagaaaaa ttttcaatat tattaccaaa
    17161 atctgaaatt ggatatataa atttacattt agtagcgtct gaccaacata gagatactaa
    17221 tgaactaaaa aatacttcaa ctaatccttg tgagacaagt acaaataata tatcaaatct
    17281 tcgggaaatt ataaaaaata cattgtatga gacagcttat gacaaggatt taattgatgg
    17341 attgacttca catgtacatt catcaataaa tagactgaaa tatggactta gtattaaaaa
    17401 tccatatgta aatacaatca aacaaaactt ttctttatca tttgagcaag ctttagattt
    17461 aaagaaagta attgaattta tatatgatat taggataaat gatgatgaat gtgcttatat
    17521 agcattacat tttgaagctt ttagagaaag aatgaaagaa cttccacaaa atattagagt
    17581 aattctagta tgcagtacag gattaggttc atctaggtta ttgtctgcaa gaataaaaaa
    17641 atactttcca atgataaaga ttgaaaaagt actttccgta caagaattag tatccagtaa
    17701 aattgatgca gatttagtaa taagtactat ttatttagag ttagaaacaa ttccaaccat
    17761 agtagttagt cctattttaa atgaaagtga tataagaacc ttggaaagaa atatacaaaa
    17821 tgtttcaagt tgtacttcta agaagtataa atctttcaga aacttaatct ttgaagaaaa
    17881 tatattgttg aatattgaag cttcaaacta tgaagatgca attaagtata taacagataa
    17941 cctaataaaa aaaggttttg caaaagaagg tatagctaaa agtgcaattg agagagaaaa
    18001 tttatcttac acttctttcc aatcaatagc tacacctcat gctaatccta gttatattaa
    18061 aaaatctaat atatctgttg caacgttaaa aaatcctatt acatggggaa atgaaaaggt
    18121 ggaagttatt ttctttattt cattagaaaa tgacaaaaac ctagagcttg atgaaatata
    18181 tgaagttttt tatgacttta ttgacaataa aaaaaatata aatgacatat taagtgcaac
    18241 ttccacaaag gaagtgtacg atttgctagt ggaggagagt atatagtgaa aatatcagat
    18301 gtattgaaaa aagagcaaat tgtttttaat cttgatacaa atacaaagga agaaacaata
    18361 aaaaaattaa gtagtatatt tgttgaaaat gggattgtgg acaatgaaga agaatatgtt
    18421 aagtctgttt tggaaagaga agaacattca actacaggta ttggtaatgg tattgctatt
    18481 cctcatggga aaagtaatgc tgtcaaaaaa tcttctataa tatttgcaaa gactaagcat
    18541 aagattgaat gggatgcttt agatgaaaaa ccagtagata gtattttctt attggctata
    18601 agcaatattg ataaggatag caatcatctt gtactattat ctaaattagc aactaaactt
    18661 atggatgatg acaatgtaga tgcactaaaa ttagccaatt cagaacaaga aataatcaat
    18721 atatttagtg aagaaggaga gatgtagaaa tgaaaagaaa aattatagca gttacagcat
    18781 gtgcaacagg agttgcacat acatatatgg cagcacaagc attaaagaaa gcttcaaaaa
    18841 agatgggtca ccttataaaa gttgaaacac aaggagctac aggaatcgat aatgagttaa
    18901 ctacaaagga tgcacaaatt gcagaagtag taatatttgc agtagatact aaagtcagaa
    18961 atgctgaacg ttttgaggga aaagaaatac tagaagtacc agttaatgca cctataaagg
    19021 atgcagagaa agtaataaat gatgcactaa agttaattga cactaaataa atggagggaa
    19081 atgtaatgtt gaaaaagata gtctctgagt taaaaaagca tgtcttaact ggaatctcat
    19141 atatgattcc attagtaatt gcaggtgcta tgataatggc gatatctcgt gtaggtggtt
    19201 ctttctataa tataccagat atatgggatg ctaaatatgc agaaagtgct agtagtattg
    19261 ttagattatt acatgattta gatgggtttg gaggtactgc attaggatta atgtttcctg
    19321 taattgctgc atttatagga ttttctatag ctgataaatt agctattgta ccaggtcttg
    19381 ttggaggtat gattgctaaa gatataggtg caggattttt aggagctttg gcagttggtc
    19441 ttatagcagg atatacatgt ttgtttatta aaaatcatgt taaattacca aaatcagcag
    19501 cttcaatagt accaatattt atagtaccag tatttgggac attaatcact gttgtattaa
    19561 tcaattatgt gataggtata ccttttgcca cattaaatac tggattagaa aattggttaa
    19621 atggattatc tggtacaaat cagatactaa tggcagctat tataggggct atgatggcag
    19681 ttgacttagg tggaccagtt aataaagcag ctttaacaac atcacttgca ttattaacaa
    19741 gtggaattta tgcgcctaac actgctgcaa tggtaggaat agttatacca ccactaggat
    19801 tgggacttgc tactatacta gcaaaacaaa aatataataa acagttacgt gaagctggga
    19861 aatcatctct tataatgggt ttaattggag taagtgaagg agcaattcct tttgcagtag
    19921 aatctccatt aaaagtaata ccttcatgtg taattggaac agcaattgct tcagctatgg
    19981 cagttggttt aggttcagta aatgcaactc caattagtgg attttatgga tggtttacag
    20041 tagagaattg gccaatgtat gtgttatcaa tagcagttgg aacagtaatt gtagctggat
    20101 tagttatagt attgcgtgga aatccagtga ttgaggatga tgaatttgaa gatgatgatt
    20161 ttgatgaagc agagtgggaa tcttaaaatt taataactat ttaagacgtg ttataagcta
    20221 tattcaatat gaatcttata ctaaataaag tgttaaatat tcagtttaga cttaaatata
    20281 aaagataaag aacagaggag aataaatgat aaaagcacat attgttaatc atacacactg
    20341 ggatagagaa tggtatttta cttctggaga tgcattagta cttagtgaac aactatttac
    20401 agatgtaatt gatgaattag aacgtaatcc agatgtaagt tttgtacttg atggacaact
    20461 ttctattttg gatgattatg tacaattaca caaagaaaaa atagaaatca ttaaaaagtt
    20521 aataaaagaa gatagactac atattggacc atggtttact caaactgatg cattctttgc
    20581 tagaggagag tctattttaa gaaacttaat gattggaatt tttgaaagta aaaagtatgg
    20641 taagtatatg aaaattgggt atttgccaga tacatttgga tttaatgcac agatgcctat
    20701 actattaaag catgtaggtc ttgataatat attcttttgg agaggtatac atcttggtaa
    20761 acaggttcaa tcaccatatt ttaagtggaa aagcttaaat ggagaaagtt atatatatgc
    20821 agtaaatatg ccacatggat atggaactgg tatgctttta gagccttcat taaagtatgt
    20881 taatggacgc ttagacccag ctattgattt tattaaatca tatactgatg tagatgaggt
    20941 gttaatacct tctgggaatg accagttaaa tataataggt gatttcaaaa ataaaattaa
    21001 agcgattaat gatatcggaa agtattcata tataacgagt tcatatcaag agtttttaaa
    21061 atatataaag tccatagaat cactagaaag ctatagaggt gaatttagag aacctgtatt
    21121 agcaagaata cataaatcaa ttggttctag tagaatggat ataaaattag catgtgataa
    21181 actagaaaac aagctgatta aaagaataga gccattatta gtaattgcta aaaagagtaa
    21241 aattgaaata agcaatcagt tacttataaa tacatggaaa aaacttttgg aaggacaagc
    21301 acacgatagt ttagctggat gtgtaactga tactgtaaca gatgatattc ttcaccgtat
    21361 aagagaagca aatgaaatat gtgacagtat tgaaaatact attgtaaaaa agatttcaga
    21421 agggattaaa ttatctaaaa atgatatttt agtattcaat acagaagcta agcgttttaa
    21481 tggatataaa gagatacaag ttgtaagtga tagtaaaaat atttatttta aagataattt
    21541 agatgctact ataattgaag aaacttatgt aaaaccgaga gaaaatgtat tagaagaaac
    21601 acctgctggt aatatattta ttgaagaacc aggatattat atattaaaag taagaataaa
    21661 tatacagctt cctgcaattg gttataaagt tgttagtttt gaattaagtg ataaagaaat
    21721 ggtgtcactt gataaatcta atgacacttt tatatctaat gataattata agataatata
    21781 tgaagatgga agcttaaatt tacaacttaa agatggaact tacatatcaa actttttaac
    21841 attaaaagat agtggtaatg caggtgatac ctatgacttt tctccactaa aaaatgatga
    21901 ggatataaaa ctttcgtttg ataaagtgta tacagaaaaa gctttaggat atgaaaaaat
    21961 ggtggttaaa ggtactactt tactaccact tacattagaa gatagaaaaa acaaatatct
    22021 taatgggaaa ttaaatgtaa aagtaagtat tgtcttatct aaagaaaacc cattgatgga
    22081 tgtaaaactt tgtgttgata acacgatata taatcataga ctacgtgttc atataaaaac
    22141 tgatataaaa gataataaaa acatagcatc attgccattt ggatatataa caagagaaaa
    22201 tggagtttta gacaactggg aagatattta cagtgaaatg cctatagatt tagaaccttt
    22261 ggaaagtaat attacgctta caaaccaaaa tagaagttgt actgtattta ctagaggaat
    22321 aaaagagtat caacatattg aagatgaaat tgcattgacc ttacttgcta ctacagatga
    22381 actaggaaag cctgatttat tatatagacc aggacgtgct tctggagata caactaaaaa
    22441 aggtcatata agaattaaaa cagataaagc tcaaatgctt aaggaattag aattttcatt
    22501 tgcaatatat atggattcta aatcatttga tgaattggaa attgcgaatt taacccacaa
    22561 ttatctaaga gaatgtgtaa attatcaatt acaggattac aatttctttt tatatcgtat
    22621 agataataag attcaaaaat caattgtcaa taaaactgta agtagagaat tagaaataat
    22681 atctttacca gaaaactatc ttatatcagc atgttatcct tcttattaca gtaaagataa
    22741 atttataata agagtggaaa atccgagtag taatagaatg atattggatg agcaaatatt
    22801 taaaaataga aatgggaaaa ttgtaaatgc aatagaagat gtagaagaag aacaggtata
    22861 tgaaatagca ccttttgacg ttatttcaat actattggat ttataagtgt aaaagtaagt
    22921 ttattgttta aagtctgaca gatattaatc tgccagactt tttaatttgt ataaatttgg
    22981 gtaaatatta atgaatggtt ttagtattta agtatgaatt tagtatttaa tatagaattt
    23041 attgaagtag aataattagt ttaacaggat aagcagttta aataaagaat tattatatta
    23101 gagtgatttt atatataatt taaaataata aaattttaat aaaatgagtg aaagattgta
    23161 tattaataga gttgatgtag ttacaaaaaa gttactaatt gttatgtatt tacaaaactg
    23221 atatattaat tacataaaat ctaaaatagt ttgtaatagg agtatatata ataaaaattt
    23281 taattaaata aagctaggta tatttataat attaataaat atattgctat aaaagtttgt
    23341 ttaataaatt aaataaagaa aagaggagaa taaaatgtac aacatagatg atatgatata
    23401 taattgtcca gtagaagctt tatcaaatat tttaggtaaa aaatgggtgg ctataattat
    23461 atggaaaata caagaagata aaaaacgatt tggagagcta caaagagcta taccagactg
    23521 tagtaagaaa atgttagttc aacaactaga ttttttaatt gaacagggga ttatagtcaa
    23581 ccaaaaaaag ttggttaata atgttgtaga gtcaacatat tttttaagtg aatcaggatt
    23641 acgattgctt cctgtcatgg aaaaaatgat tatgtggagc aataaaaatt taaattgtga
    23701 taaatactaa aatttactct gtaagtaatg aaaatttaat taagctatga gtagaaaaat
    23761 gtattaaaat tacataattt tttagttaga ttttaattta gaaataggat tgtaatattg
    23821 gaaataaaat aaggaggaat tttaatttgc aaaatgtaaa tttattttta gtatttatag
    23881 aaggtatagt atcattcttt tcaccatgta tactgccaat tttgcctatt tatttgagta
    23941 tattgtcaaa tagtagtgta gaaaatttaa aagaaggaaa gacgagtttt ataggaagtt
    24001 ctttatttaa aaatactata ttttttgctc ttggaatctc aacaacattc tttatattgg
    24061 gttcatcagt aaaagtattg agtatgtttt ttaatgaaaa taaagattta ataatgttta
    24121 ttggtgggat tataattatt atcatgggat tattttacat gggaataatt aaatcttcaa
    24181 tattgaatag agaaaaaaga tttaatgtta agtttaaaga aatgaaagca ataacagctt
    24241 ttatattagg ttttacgttt agttttggat ggacaccttg tattggtcca atattggcat
    24301 ctgtattagt catggtttca agttcaagta atcatcttag tgccaatctt ttaatagcag
    24361 tatatactat tggttttatt ttgccattca taattacagc tatgttttac agtaaactat
    24421 ttaaaactat agataagata agatctaaca tggaaattat taaaaaaata ggtgggatta
    24481 tacttatagt atcaggaata ttaatgatgg taaatggatt tggaagtata agcaaacact
    24541 ttaatacgtc acaaaatagt aaaattgaaa gcaagcaaga agaaaataag cgagaaaatt
    24601 ctactgataa agaagaaaat tctgatggta atgatagtca aaaagactct aataatgaca
    24661 ataatgataa agggtctaat gatgaagata gaataaagtc tattgatttt actttaacag
    24721 accagtatgg taaaacacat aaattaagtg attatgaagg caaagttgta ttcttaaatt
    24781 tctgggctac atggtgtcct ccatgcaaag aagaaatgcc ttatatagaa caactgtata
    24841 aagactataa taaaaataat gatgatgtag taattttagg agtagcttca cctaatttag
    24901 gtagagaagg ttcaagggaa catgtagtta acttcttaaa agaccaaggt tatacattcc
    24961 ctgttgtact tgatgaagat ggagcattag catatcaata tggaattaat gcttttccaa
    25021 ctacatttat aattgacaag gaaggatatg taactcagta tattccagga gctatggata
    25081 aggcaactat ggcatcattt attgaaaatc agagaaataa ataaaagtat ttaagtataa
    25141 gtttataaat caatttaagg ttacaaaaaa gtgcctaatt gtaccaccta aataatcttg
    25201 ttatagtaaa agtataaaca atacaagaaa gggttgaatt ttatatgaaa aaaacatttg
    25261 atgctataat aataggattt ggaaaaggtg gaaaaacatt agcaggggat ttggcaaaca
    25321 ggggattaaa agtagcttta atagaaaagt caaacaagat gtatggtgga acatgtgtaa
    25381 atgtggcatg tataccaaca aaaagcttag aaaattcagc aaacagcgta aaaacaaaga
    25441 atataaattc ttgggatgaa gtacaagctg aatatgagaa agctatagat aaaaaagaaa
    25501 ctttaattac aaaactcaga gaagctaact ataataaatt aaattcaaat gagaatgtaa
    25561 ctatattcac aggaatggga actttcattg atgaaaaaac agttcaagtc aaaactgaaa
    25621 atgaaattta tgagttagta gcagataata tatttattaa tactggttca agaccattta
    25681 tacctaatat taagggaatt gaaaataaga atatagtata tgatagtgag tctcttatga
    25741 atctaagaac tttacctaaa aaaatgacaa ttataggagc tggatttata ggtttagaat
    25801 ttgctggtat ttatagttca tttggagcag aagttacaat attaaactct aataatggca
    25861 ttttaccaaa tgaagatgtt gaggattcag aagaaataat aaaattactt gcaaagagaa
    25921 atgtaaaaat tgttaataat gcaaatataa aagagattaa agaagtttct gaattagcaa
    25981 tagtagaata tgaagtagat ggtaaatcta aagaattaac aagtaatatg atacttgtag
    26041 ctacaggaag aaaagcaaac actgaagggc tagggctaga aaatgcaggt atagaattaa
    26101 atgaaagagg atttattaaa gtctcagaaa ctcttaagac taataaagag catatatggg
    26161 ctataggaga tataaatgga ggtccacaat ttacttatat ttcattggat gattatcgca
    26221 tagttattaa tcagttattt ggagataaga ctagaacaac taatgataga aagaatatcc
    26281 caaattctat atttataagt ccagcatttt caagagttgg tcttaatgtt aagcaagcta
    26341 aagaaaaggg atatgaagta ttagtggcaa agatgccagt agaagcaatt ccaagagcta
    26401 aacagattgg caaggcagat gggtttataa aaatagtgat agataaaaaa tccaataaga
    26461 tacttggagc tagtatgata tgtgaaaatt caagtgagat tatccatctt attcaattag
    26521 ctgtagattt agaagtagag tatacatatt taagagaccg tgtttatgca catccaacta
    26581 tgacagaagc tcttaatgat attctatctc ctaatatgat aaaagaagta taacataagt
    26641 ttaatatata aacctaaaat tatcattata agtagatttt agaaagaggc tatctcaaaa
    26701 aatagagata agtctctttt ttactgttta aatgataaaa atatatttga ttttataaaa
    26761 gaagattatc ttatgaacta aaaagtttat tttaaaacac tacctattta tgttataaac
    26821 ttataaatat aatatagaat ctattattct gtattattaa gtggggttaa gcgttataat
    26881 taattataaa tattgaataa tctaaatgga taagataatg gtattaaaaa ttatcttaaa
    26941 aggtgaaata atctgtattt aatgtagtac agttatatct ttaaagcaag gtggtgaaat
    27001 gatataaata agatatctaa aagagggttt gatgatagtg ataaaagatg gttttcaagt
    27061 aaagaattaa caagacttat aaaggctaaa gaagaaatag aatggttatt aaatagggat
    27121 tacaaaatag acccagtcgt tacttttgtt ggtgatagat atcagttttc tataagacaa
    27181 agagatgcat taaaaagggc agtctgtact gatgaaaaaa atattataag acaatcaaag
    27241 aggctttctc tagataaaat caaagaagat accgtaaata tagatggctt taatttgata
    27301 atatccatag aggtagcatt atctggtggt actctagtaa taggaagtga tggcaatata
    27361 agagatttag caggtcttag gggaacctat aagattatag ataaaacaga agaagctttg
    27421 aatctgatag gtaaattttt taataaatac aatgcacaga atcttaaatt ttatttagat
    27481 gctccagttt ctaattcagg aaatttaaag tataggatat tagagcatgc caaaacttgg
    27541 ggaattgaaa ctgaagtaga attagtaaaa aatgcagatg ttgtattaga aaaattagat
    27601 agagtagtta gtagtgatgc agtcatagtt gacaagtgta taagttattt taatgtggct
    27661 agaggtataa ttgaagagta tattaaagaa tgtaatatca taaatttaaa taaatagata
    27721 aatataggtg agaatatata agtatatgta gcaatattat tagtaataca agtaaagttt
    27781 gaaaatagga gaacgaatac atatcgaatt tcataaaatg ttgtaaaaag acatatgaga
    27841 ggatggatat gtgtgaaatt aactaaacta aatattaaaa aatatagagc acctatatat
    27901 aaatatgctt tagcaaatgt aaatttgagg tctgctaaat ctaccaattc aagtatcata
    27961 acagtaatac ctcagggagc taaaatggaa gtattggatg aagaagatga ctggattaag
    28021 gtgatgtaca attctcaaga aggatatgtg tataaggatt tggtatcagt aagcgaatat
    28081 gcttggagta acttaaactt aagagaagat aaatctacaa cttccaatat aattacagta
    28141 attcctgaaa aatctagggt tgaagtcctt caagtagatg gagattggag taaggttgta
    28201 tatgatgata aaataggata tgtttttaat tattttttat caattgatgg gaataaacca
    28261 aatgaattag attataagta tttttatact gacatgatta aatttgttaa cgaaaataat
    28321 attaaaagta ctagcgatta tctaattgta acagacctta gaaataaata tacttatatt
    28381 tttaagaaag ataatggagg ctggggacaa ctttacaagt ggcaatgtac tataggtaag
    28441 cctgagactc caactataac aggtatattt tatataagtg gaagaaaacc ttcttttgga
    28501 acggatgagt attcagttaa atatgctact agaattaaag gtggatatta ctatcattct
    28561 gtgctatatg attcaacagg aagttatata atagatggca gacttggtga agctcttagt
    28621 catggatgta taagattaag tacggaaaat gcaaagtgga tatatgataa tataccagat
    28681 acaacaacag ttataattca ttaagaaaaa ttttgagttt tttattggga taatgattct
    28741 taaattaata ggattatata ttaacttctc ataaagagta ctatttaaaa agtgtaataa
    28801 gagagtgcta ttaacaaaac aaagatattt tgaggcactc tcttataaat atacataatt
    28861 aagatatttt cataaacaat tctataatct tatctttatc aaagaaaaca ggattagcac
    28921 cagcacaagc atctttcata gagttttctg caagcaattc aaaattagga ttatcaacac
    28981 ctacatcttt taaagatttt gggattccaa cctcttcaga aagagctttt atcttatcta
    29041 ttacaaagtc aacacactct ttatctgatt tattatttac atccattcca ataacttcag
    29101 ctattggtcg gaatttggca ggggctgatt tagcattttc ctcctcaact attggaagta
    29161 gcatggcatt acatactcca tgaggtaaat catataaacc tcctaattga tgagccatag
    29221 catgtacatt tccaagacct gcattactaa aggcaattcc atttaaaaaa caagcataac
    29281 acatttgttc tctagcttct atgtcattac catttttaac agctcttgga aggtatttaa
    29341 atatctgctt tatagcatat aaggcagttg aatctgtaac atcataagca ccattagcta
    29401 ctacagcttc tatagcatga gttagtgcat ccataccagt tgctgctgtt aaattagatg
    29461 gtttgctaat cattaattct gggtcattta ctgtcattgt ggctagtgaa ttggtatcaa
    29521 ccattatcat ctttacatgt ctgtcttcat cagttataac atagtttatt gtaacttcag
    29581 cagatgtacc agcagtagta gttatagcta tgataggaag acatttttta gaagttttgt
    29641 tgataccttc atagtctcta atatctcctc cattagtggc taatatagag atagctttac
    29701 cacagtcttg tggagaacca cctcctatag ttataacgaa gtcgcaattt tctgatttta
    29761 atattttaag tcctttattc acattagtta cagttggatt ttgtttaact tcatcataaa
    29821 caacaaagtc tatatctatc tgagataaaa tatctgttac tttttttaca gtaccatttg
    29881 aaactagaaa tttatcacta acaataaatg cttttttagt tcctaatgat ttaattgaat
    29941 ctttagcttc attaagacat cctttcccaa gtaaatttat tggtggtaca taataaatgc
    30001 tcataactaa aatctccttt tattttcatt gatttttatg taaaaatata tatctaacaa
    30061 ttttcactaa tttactcata atatatcgta tcttagattg agatagggtt gctgattctt
    30121 atataagaac ttaattcgta attacgatta tgattagaat ttaacatagt atttttatca
    30181 tgtcaataaa aatataaaaa atattataaa aaaaacaaag ttactgtagt taaatcagca
    30241 actttgtttt tatagtataa atcaaataaa tacattagtt taaaacaaaa tttttaatta
    30301 ttatgttttg atatcttcca tataaagaat attaatctaa tttattacaa tgtcttcatt
    30361 acgttcttcc atcattgatt gaatattttt ctgagcattt aagagtaatt tttttatcag
    30421 ttctattttt tcgtcattag ctctaaataa aggcagtgtt acactaacag cagctcttat
    30481 acatccattt tttcttattg gtacggcaag acattttagg tgttccattg attcctcaca
    30541 ctctgaagct atttgtgttc tttgaacttc aagaagctgg tcgtataaaa catcaaaatc
    30601 tgtaattgat ttttctgtaa aaccttttag accatctgga tataagctta ttagtttttc
    30661 cttgtcaaaa tcacataaaa gagcttttcc aagacctgta caattagcag gtattttttt
    30721 tccaacataa gaaataagtc taatcggttc tggagaatct acttttccaa tataaagaac
    30781 ttcattattg tcaagtatac caagctgaca agtttcagaa caggaattaa ctatattagt
    30841 catttcgtca attatatagt taaaaatagt tcttttttca aaaaatgaag accctaatgt
    30901 gtaagaacgt atccctatag aatatttgga tgtgttttta tcaatagtaa tgtattttct
    30961 agcattaagt gtatgaacta taggaaagat gctacttttt ggagcattga taacatctgc
    31021 tatttctgta agagtatatc cattttcgga ttctgctaat gcttctaaaa tatctaatat
    31081 cctagctgtt gggcgatgat tatctgaagt cataaatttc cccctctttt tattaattta
    31141 aagtattaga atatgttgat tttagcacac tatacgatat tttacaatgt agaaaataaa
    31201 tatgtaaatt tatatataaa taagctcttg atttagatac agatagatat ttttttagac
    31261 tgtacattaa ggaataacta atttccaaaa tatacctaaa gaaagtaagt gatatttagt
    31321 tatataattt aagtaaatat atgcaatagt tatttttata tgtaaatatc aaaatattat
    31381 gaacttatat tttatctatt ttttacactg tataaaaact ttatagtttt gaatactata
    31441 taattttaaa tacgctgtat ttttgcatat aaggaagtca tttgataata tacaaggtat
    31501 tatcagaaag tttgaaaaaa ttttgacaaa aatttatttt ttttattgac tcataaatag
    31561 gaaaatgcta tcattaattc aaagattcgt aattaaaaac ttagttctta aatacgaacc
    31621 gaaacggccg ttagaattaa agctaaaaac ttaataagag taattaaata tcatgtttta
    31681 ggaggattaa ctttatgata atggatttta ttaaaaaaat tcctgcaggt atgatgatag
    31741 tgccaatgtt tatagcagct ttcattaata ccttttgccc agatattgta caaataggtt
    31801 cgtttacgac agcagtattt tcaagtgttg ggtctgcaac tataattggg gttcaactgg
    31861 tatgcttggg aactcagctt caatttagag aaatgccaaa agttttaaag agaggtggta
    31921 tacttcttgg ttctaaattt gctataggtg ctttgatagg tatacttata ggaaagctat
    31981 ttggaatgga tggtgtcctt ggtctgacaa cattggctgt tataagtgca gttacaaata
    32041 gtaatggtag tatatatctt tcattgatga cttcatatgg agatgaaaca gattgtgcaa
    32101 ctatgagttt acttacttta aatgatggac cattttttac attaatagct cttgggactt
    32161 caggtcttgc aaatgtacca ttgttgtcat tattggctgc aatagtgcca atacttgttg
    32221 gtatgataat aggaaatttt gacaaaaaaa tgaaagagtt tttagagcca gggtgtaatt
    32281 tactcgtacc ttttgtaggg tttgcacttg gtagtagcat aaatcttgca agtatactaa
    32341 aaggaggttt atcaggagta ttacttggat taatatctgt atttgtagga ggtatattta
    32401 tagtattctg tgataaattt ataggaaaac gtccaggata tgcaggatgg gctgtagcta
    32461 caactgctgg aaatgcaatt gctgtacctg ctgctgttgc attagttgac ccatcatggc
    32521 aaccatatgt tgcaacagct acaacacaag tggcagccgc agtagttgtc actgcaatat
    32581 tagtacctct tataactagt tggtgggcta agaagtatgg atgtcctaag ttcccaaaac
    32641 aaaatgagga tggtacaata acagcttaat ttatattaca gtgagttgtt ggtaaaataa
    32701 taaattcttt aattagattt taggatatta ataaaattat attatttata aaggagagca
    32761 agaataatga taaatgcagt gataattgat gaaaaagata atgttgcagt agctattgaa
    32821 gcaatagcta aaggtagtga aattagtttt aaattaaaag acaaaacagt aaaaacgatt
    32881 acagcactag atgatataac tatttatcat aaattggcta taaaagatat ggccaaaggt
    32941 gataaagtta ctaaatatgg tgaacatata ggagaagcaa atcaggaaat aaaaagtggt
    33001 caacatgtac atattcataa tgttagaagt gttagagagg atttggataa acaagttatg
    33061 actaatatat aaaataatat ttatagagtt ataaaagttg tattcattgc ttttagtgtc
    33121 aaatagtttt taaataggtt tttagctgtt tgattagtga gtgtaataaa aattataata
    33181 tataaaaatt atagaaagta tatagactat tttaggagga aatcagtatg aaattttatg
    33241 gatataaaag accagatgga agagttggta taagaaacca catattaata ttgcctacga
    33301 gtgtgtgtgc atcagataca actagaataa tagcatcaca agttcaaggg gcagttacct
    33361 ttaataatca gaatggatgt tcacaagtac attcagacca acaattaact atggatgtta
    33421 tggctggtta tgcagcaaat ccaaatgtat atggtgtaat agttgtatct ttgggatgtg
    33481 aaaattgcca aaatgatttg gtagttgatg caataaaaga gagaacaaat aagccaataa
    33541 aaactcttgt aatacaagaa gaacatggaa ctttaaaaac tatagaaaaa gctgttcgtt
    33601 atgctagaga aatggcacaa gaagcttctt tgcttataaa agaagaattt ccaatatctg
    33661 aacttatact aggaactgaa tgtggtgggt ctgacccaac aagtggatta gcagcaaatc
    33721 cattaatagg tgaattaagt gataaacttg tcgatttagg agcaacatca attttaagtg
    33781 aaactactga atttataggt gcagagcata tactagctag gagagcagta aatgaagaag
    33841 taaaagaaaa aatattacat atagtacata gatatgaaaa ttcattaaaa ttggttggag
    33901 aagaagttag agaaggtaat ccatctcctg gaaatatagc tggtggttta acaagtttag
    33961 aagaaaaatc acttggttgt atacataaag gtggtcatag acaaataagt gaagtatatg
    34021 attatgccaa acaaattgat aagaaaggtc ttgttataat ggatacccct ggaaatgatg
    34081 cttcatctgt tgctggtatg gtagcaggag gagcacaaat agtggtattt agtacaggaa
    34141 gaggaacacc atcaggaaat ccaatagcac cagtaataaa aataactgga aataaaataa
    34201 cttttgcaaa tatggaagat aatatggatt ttgatgctag tccagttata tatggtccac
    34261 aaacaatgga agaattaaca gatgatttgt taaatatggt tgtagatgta gcaaatggaa
    34321 aacaatcaaa agcagagtcc cttggatata ctgaaatggc aatagctaga gtatgcaact
    34381 atgtataatc tttaagtaag aaaataaata catagaattt taataaaggg tgagattatg
    34441 aagtttgtaa gttttactga aggagaaaat gaatgtaaaa gaactggagt tttttctaaa
    34501 gatgaattat ttattataga tgttaactct ttaaatctca gtagaaattt taaggattta
    34561 aatgaattaa ttcaaaatgt atctagtgaa gatattatta agttgaaaac tattataaat
    34621 gaaagtacat tctataatta tgatgttttt aaaagagaga gatgtactgt acatgttcct
    34681 atagaaaaac caatacatga tatcttatgt gtgggagtga actataaaga ccatcttgaa
    34741 gaaactcaaa ctcactttga tgatagtttt gaagaaccac aaaaaacggt ttattttaca
    34801 aaacgtgtga caaaggcaat aggtccagaa gatgagatag atggtcattt tgagataaat
    34861 aatcaactag actatgaagt tgaacttgga gtagtaatag gtaaaacagg tgttaatatt
    34921 agaaaagaag aggtagaaga ttatatcttt ggttacactg ttataaatga tatttctgct
    34981 agaaagttgc aaaaagaaca tgttcaatgg tttagaggaa aaggattaga tacatttacc
    35041 tctttaggtc catgtatttt acataaaagt gcagttcctt ttcctataaa acttaaagta
    35101 tgtagtaggg taaatggtga agaaagacaa agttctaata caggattatt catatcagac
    35161 gtttcagaca tagtttcaga actttcaaaa ggtatgacct tagaggctgg agacattata
    35221 gctactggaa caccttctgg agtagggatg ggattttcac ctcctcgata tatgagtagt
    35281 ggagatgtag ttgaatgtga gattgagagt attggaattt taaaaaatta cattaagtaa
    35341 ctgttttaat ataattaata ttaaagctaa atctgatgta ttaatgaaca tattaaaata
    35401 aattttagga gtttaaatta tgaaagcaga atttttgaca ccagttgtta caatatttga
    35461 tgaagaagga aatttagata aagaaggtaa taaaaaagtg tatgaccatc ttatagatgg
    35521 aggtgtagat ggactagtca taatgggaag tactggagag ttctttaata tgtctatgga
    35581 tatgcaaaaa gaacttatag atttagtaac tagtcatgta aataagagag taaaagtgtt
    35641 tataggtaca agtcgtatgt gtataaatga atctatagaa ctttcaaact atgcacataa
    35701 tagtggagca gatggtgtta tgataataag cccttattat ttctctcttg atgatgatag
    35761 tattgagtta ttttatagtg aaatagctaa gaatacagag gctgaaatat atttgtacaa
    35821 ttatccagat agaactggtt atgatttaag tccagaactt acattaagac ttgcaagaaa
    35881 acataaaaac atagttggat ataaggatac agtaactttg atgggacata ccagagattt
    35941 aataaatact atgaaaatag agttcccaga atttaaggtt tatagcggtt atgatgaaaa
    36001 ctttatacat aatctaatgt ctgggggagc aggttgtata gggggattat caaatttaat
    36061 tccagaagtt tgctccaaat gggctgaagc ttacaataat agagatatgg agaaggttat
    36121 agaaattcaa aaatatatta ataaagcaat ggatttttac ttaataacca atccatttat
    36181 accagcaatg aaaaaagcta tgaatatcag agggttacaa ataagtgatt atatgactgc
    36241 tccatttgta aaaccaaatg aaaaacaagt atgtgaaatt aaaaaattga tgaatgaatt
    36301 aaatatatgt taaatcaacc ttgcaaagag gtcaacaata aattacaatt atcttaataa
    36361 aaattaaatt aaaataatac tagggtacta tattagttta atagggaaag tgatgaaaat
    36421 tcactacagc ccccgctact gtatacggat acgaaatcaa aatccactga aatttataaa
    36481 aattttggga agggtgatgg aggaaaagcc gtgagtcagg agacctgccc agtattatat
    36541 aagttcaatt tagggtggag attgtaattt ataataaaat gaagtatcaa ttcgtttttg
    36601 taaagttgat atatgaactt ctccttatta aattaggaga agttttttat tttattaaaa
    36661 ggttatactt attaaagatg actttaggat aactttaata agtatacttt aaaaagcata
    36721 tattattaaa gttttttagc cactcataaa aaataagata ttggagtgaa agagatgaaa
    36781 tttaaatcaa atgttttaaa gcagtttttt ttaattgcta tggtaatttt tatggtagga
    36841 ggtcttatag ggtgtagtaa aagtgacaaa gagaataaac aagctagtac tggtaagaaa
    36901 ttagaattaa aatatgctag tggatttagt gttgaagatt tagaagatgg aattaaaaaa
    36961 gtaactgatg gagataatcg agaactgatt ttaatcccaa agaagattaa aattcctgaa
    37021 aaatataaaa atgctaatat agttagaacg cctgtggaca atgtattaat agcatctaca
    37081 acacaggctt gttctctgag aacaatagat gaactagata gtataaaagc agtaacaaca
    37141 gaagagcagt actggactat taaagaaatt aaagatttaa tgaaagatgg aaaaatacat
    37201 tacgttggtt caaatttagc accagattat gaaaaaatag tagacttaaa tcctgactta
    37261 actatagtta gtagtggttt atcagaggct gatacaaaat ttattgacaa attaaaagaa
    37321 ttagggctta attatgttgt agacaatgag tataaagagc aaaatccatt tggaagaatg
    37381 gagtggacaa gtttaatagc tgcattttat gataaagaag atatggctac tagtgaacta
    37441 aataaaactg tacaaaaggt agaagaagta agtaaaaaaa taaaaaacaa agctaaacct
    37501 aaagttgtat gggcatctgt atatgaagga agtgcttata tagctcctaa agattcatat
    37561 gtggataata tgataaaaat ggctggtgga ataaatgcat gtgcttcaat agattcaaat
    37621 gaagggcgag taagtattga acaattgcat gaagttgcaa aagatgcaga tatatttgta
    37681 tactcatcaa gttcagatta tgcaccaaat ttagattcta taaaatctag tgcacctgta
    37741 ttggctgatt tggatgttgt aaaaaacgga aacctatggg tgtttgctcc agattattat
    37801 caatcagtag ataagacaga cgaattaata gtagatttag ttgagatgtt ccacccaggt
    37861 actacaggtg aaaaaatcaa acattatata aattatgata aatagtacag agaggacaca
    37921 aaaagatagg ttttatagat tttagttaat atagctttgc taagaggagt atacaaatgg
    37981 attttatcaa taaaatgaga ataaggaata cgacaatatt tatagtatta attataagta
    38041 tgatacttac ttttttagtg tgtgtagcat ttggctctgt aaaaattgaa tttaaagaag
    38101 taatagatgt tgtattaaga ggtatggata atacagaaca ttataaaata atatacaata
    38161 taagaatccc tagagtactt gcaaccatgg taggtggagc atgcctagca gtatcaggta
    38221 ttttattaca gatatttttt aaaaacccaa tagttgaacc gtatatatta ggagtatctt
    38281 cgggttctac tttatcagta gctctcatga ttttgggagg atacacattg ggatttgaga
    38341 gtgtaaattc aatgagtata tttgtagcag cttttatagg agctttaatt gtaatgtcta
    38401 tagtcatttt atttgcaaat aaggtaaaga atataacaac tcttttaata ataggaatta
    38461 tgaccggata tgtatgtagt ggtataacaa atgtgttaca atcatttgca aatagtgata
    38521 aattaaaaga atttactatg tggtctatgg gaagtttttc tggatttaca tgggaaaagg
    38581 tagaaatact tataatagtt ggtatattag gtcttttgat gactgtattc ataataaaac
    38641 ctttaaatgc ttttttacta ggagaagagt atgcaaaaag tattggcata aatataagat
    38701 tttttagagt tttgatagta tttatatcta gtatattagc agcaatagta tcagcatttg
    38761 caggacctat agggtttatt ggacttgcag tgccacaaat ttcaaaaatg atatttaaaa
    38821 catcagataa tagagttttg ataccagtag taatattttt aggcagtata gttacagctc
    38881 tttgtgattt aatatcaaga gtaattttat caccagtaga attaccaata agtacgataa
    38941 catctttatt aggagctcca attgtagtaa tgttattggt gaaaaggaag gatagggctt
    39001 agacatgttg aaaactaata atttaagtgt aggatacaat aacaaagttg ttataagtaa
    39061 tataaatgta gaagtaaaaa atggagaaat actatgtctt ttgggaagta atggagctgg
    39121 aaaaactacc ctattaaggt ccttatctaa acttatatca ccaataaaag gtgaaatata
    39181 tttgaatggt gtaaacataa attgtatatc aagaaaagca ttatcaaaaa aaatggcttt
    39241 agtacttaca aatagattat taggtgattt aatgactgta caagatatag tcaatatagg
    39301 aaggtatcca tatacaggat tttttgggag tctatctaag aaagatttaa taatggtaga
    39361 tgaagcattg gagtctgtag atgccttaca tttaaagaaa agatattttg atgaactaag
    39421 tgatggagaa aaacaaaagg tgttggttgc aagggctctt gttcaagaac cagaaataat
    39481 tatattagat gagcctacaa ctcacttgga tataaaacat agattggaac tcataaacat
    39541 actgaaaaaa ttaagtaaag aaaagtcaat atcagtaata ctttcattgc atgaaataga
    39601 catagcatta aaaagttgtg ataaagttgc tcttataaaa aataataaag tcatagctta
    39661 tggtcagcct gaagatgtag tagatgagga tattataaat tcgctttatg aattggatga
    39721 taaaaacttt aatagtcttt taggttcagt agaaattagt aataaatcta aaaatgaagt
    39781 ttttataatt ggtggtgggg gtaaagcaac accaatttat agagctttta ctaaaaaagg
    39841 tataggtctg tattctggaa taatacatga aaatgatatt gattatgaaa ttggtagaac
    39901 tatggggata aagatgttta cagaaaatcc atttgagcct ataagtgatg agagtttcga
    39961 tttggctatt agaaatttaa atgattccaa gattataata gatacaggat ttagtgtagg
    40021 agagacaaat aagaggaata tagatattat aaaagaggct ttaaaattgg ataaaaaagt
    40081 ttattctttt agaaatagag atgagagtaa gaagtattat gacagtttgg atagtaagat
    40141 agaacatata gataaagttt ctcaaataat caatagtgca gatataaata atttattata
    40201 atttatgaaa taaaatgtac ttatgtgcta tagaaaaaag agtatagatt ataatttttt
    40261 tgaaattaca atctatactc ttttgttatt ttgtttatgt atttatatat ttataaaact
    40321 ttagcatttt atagataacc aatagcttcc tctctagtta aaaaaaagtg aatccctgta
    40381 gtcgattctt tccatctatt ttcattaaaa tcttcagcta caatcgtttc tcctactcta
    40441 tatataaaat tttcatcagc atatgcacga gcacttttaa aagattcttt accatctata
    40501 ctagtaattg acagtacttt tgccttatca catctacaag cgtttgatgt agcagacact
    40561 ctttttgcgt cgctgggtat taataattgt accattctaa aattaaaaca ttttttatag
    40621 cctataaatg ctcctgtttc aggacaatac aatttaaaaa aacgggtact ttcatctgat
    40681 attactccat ttaaagtagc atgttctaaa tttgaatttt ctaaattagc tcctctaata
    40741 tctgagttag ataagtcaca aaatctaaaa cttgcaccac ttaagtctgc attttttaat
    40801 atagaatttt ttaatgaaca atccgaaaga taagaattat taaaaataga gttttctaaa
    40861 tctgcttttt ctaaatttaa attgataagg tcagaccacg aaaagtcaat attacttaag
    40921 cagtatcttc ttaagtccat attttctaat cttaattctt ttaaatctgc cttttctcca
    40981 gcattattgt ttttaagcca taaataatgt ttctcaagtg ttttttctaa ttcttgttta
    41041 gaaatagttt tcattaaaat caccttcata aatttatttt tatatatgta gtagcaaaat
    41101 agtcatatat ttaattatat aacaataaat aaaaaacttc taaataatat ataaaatatc
    41161 atcttgaaag tacttttttc aatatatcag aatatatttt taagctattt agagataatt
    41221 taaattttta aacaggacat aataagcttg tattgtttta tatttgagtt gataaaaatt
    41281 tctttaaata aaaataatgt caattataaa gtaataaaag tttagatata aaaaaatttg
    41341 tgtatatact atatgtagta tataatagat aaagcactga ctatatgtag tgcttttgtt
    41401 tttgaaaaat acttattgca tttctataat tatagattaa ttttgggatt tcaactgata
    41461 agtaccaaaa gaaataataa gcaaattaag tgaaattatg gcacaagatt atgttaaaag
    41521 gacggtaaat aatgaattgg atagagctta acaatcaagt gataattaaa aatgaacaag
    41581 gcaagtacca attggaaaag gataaggaag ccttaagtag ttacatagaa gaatttatac
    41641 agccaaagtt gagaaaattt aataacctag aagaaagatt gaagtattta atagatgaag
    41701 gttattattc aaaagaagta ataaatcagt atagcataga tgttattaaa aatatatatg
    41761 atatgattga taaacataag tttgaatttc aatcatatat gagtgcaaat aagttttatc
    41821 aaaattatgc attaaagagc aatgatggaa aggaaatatt agaaacatat aatgataaag
    41881 tgttaattgt agctttgaca ctaggaaatg gcgataaaga tttagcttta aacttggcag
    41941 ataaaatagt aaaacaagaa tttcaaccag ctacacctac ttttttaaat gctggaagaa
    42001 aaagggctgg agaaatggta tcatgttttt tactatctgt agaagatagt acagaaggta
    42061 tatcgtatgc tatatcttca tcaaatcact tatcaaagat tggtggagga gttgcactaa
    42121 atttatctaa acttagagca tctggcgaat ctatcaaaga tatagaaggt gcagctggag
    42181 gtgttgttgg agtagctaaa atgttagaac aatcatttag ttactttaat caaatgggag
    42241 ctagacaagg ttctggtgcg gtgtacctta ctgtattcca tcctgatttt gaattgttga
    42301 tggatactaa aaagataaat gcagatgaaa aaataagact tgctacatta tcattaggag
    42361 ctataatacc agataaattt atggagttgg cagaaaaaaa tgaagtagca tatgcatttt
    42421 atcctcatac tgtgtataag aaatatggag tttctcttga tgagatagaa atggatgagt
    42481 ggtatgataa attggttaat gatagtgata taagaaaaaa agaaataaat cctaggcaga
    42541 tgttgacaaa aatagcacag atgcaacaag aaagtggata tccatatgta gtgtacatag
    42601 atacagctaa tagagaacat acattaaaag atgttggaat tattaaaatg tctaacttat
    42661 gttgtgagat atttcaatat caaacacctt cagaaataga ggggtatgga ggaaaaaatg
    42721 aatggggaca agatataagt tgtaacctag gttctttaaa catagctaat gtaatggata
    42781 ataaaactat agaaagtaca gttgaaacag caataagagc actgtcattt gtagcagata
    42841 gcacagatat aaaaccagtg ccaacggtaa gcaatagtaa cagcaagtct cattctatag
    42901 gattaggagc tatgaattta catggatact tagtaagaga aaatatttta tatacttcag
    42961 atgatgctat agatttttct aatgtatttt ttgcaatggt tagatactat tcaattaaag
    43021 cttctatgaa aatagctata gaaagaaatc aaacttttga aggatttgat aaatcagaat
    43081 atgttaaggg aagaaatagc aaggttttat caaaatacta tgaacaatct tatctaccta
    43141 agtcagaaaa ggtaagagca ttatttgaag ggatttatat accaacaaaa gaagactgga
    43201 caaaattatt ggatgaggta aaagaaaaag ggatatataa tgcatattta atggcagtag
    43261 caccaactca aagcattagt tatgttcaaa atgctacatc aagtataatg ccaattactg
    43321 agccagtaga agtaagaaca tatggagact ctactacaat atatccaatg ccatttttaa
    43381 caaatgataa tatgttgtat tatcaatcag catacaggat ggatatgaga aaggtcatag
    43441 atttagtggc aacagttcaa aaccatgttg accaaggtat atcaacaaca ctgtttgtta
    43501 cagatgaaaa gacaactaga gatatagcta gacattacat atatgcctat aaaaaaggtt
    43561 tgaaaagttt atattacaca agaacaaaga tgacaagaga tactcatgag tgtctagtgt
    43621 gttcagtata gggagagaaa tatatgacat ttaatttaca taaaatacat aatgcagtta
    43681 actggaatag agaagaagat ggatttacac aagctttttg ggaacaaaat gtaaaacaat
    43741 tttggcttcc tgaagaaata tctgtttcta aagacataaa ggtatggaat gaactaagta
    43801 ataaagaaaa ggaattatat aaaaaagtat tgggtggttt aacattactg gatacaaaac
    43861 aggggaataa tggaatacca tctatgatga gtttaacaga aaacctacaa agaaaagctg
    43921 tcttgtcttt tatggggact atggaagaaa tacatgcaaa aagttattct tctatattta
    43981 tgactctact ttctaattta gaaatagatg aattatttga atggatagaa acagaaccaa
    44041 cattacaaag aaaggctgat ttagttttag ctcaatacga aaatactaca aatcaagagg
    44101 gattatacct atcaatggtt acaagtgtat ttttagagag tttcttgttt tattcaggat
    44161 tcttttatcc attgtatcta tctggtcaag gaaagatggt agctagtgga gaaataatat
    44221 cgcttattct tagagatgag tctttacatg gtaagtatat aggattgcta gcacaagaaa
    44281 tatacgattc atttgataaa atggataagg agatgttaga agagaagatg tattctatac
    44341 tttatagcct tatggagaat gagatagagt atacaaatgt tatatacaga gaaagtgggc
    44401 ttgaaaaaga ggttgtgaac tttttaaaat acaatgcaaa tagagcttta gaaaatctag
    44461 ggtttgagaa gctatatact gtagatgcta taaatccaat tgtattaaat ggtcttagca
    44521 ctgaaaccaa aacacatgat ttcttttcaa ctaagggtaa tggataccaa aaaggagtgt
    44581 atgaggaatt agaggatgaa gattttataa tataatttat aattatgaca cactgttgtc
    44641 acttttagcg tgataatatc aatgtataaa atatatatgg aggtattttt atgaaatatg
    44701 aatggagaaa aagagataaa gagttatatt tacctaaaaa gaatcctgta atagttgaaa
    44761 taccagaaca gaaatttatc atgttaaaag ggagtggaga cccaaattct aaagaattta
    44821 ctgaagcaat aggagtactt tattctttgg catatgcaat aaaaacaatg cctaaaaaag
    44881 gaattgtacc agaagggtat tttgactata cggtttttcc tttagaaggt atatgggata
    44941 agggagaaaa aagtaaaggc ttagatgtac ttattaaaga agatttaatt tacactataa
    45001 tgatacgtca gccagatttt gttacacaag acctgttgga taaagctact gatatagtaa
    45061 agaagaaaaa acctcataat cttcttgaaa aagttagatt tgggtctatt aatgaagggc
    45121 tatgtgttca aatgcttcat ataggttcat atgataatga accagaaagc tttgacatta
    45181 tgaacgaatt ttgcaaaaaa aataaactta taagaaaatc ttacacacat cgtgaaattt
    45241 atataagtga tgctagaaaa gtatcgcctg aatcattgaa gacggtttta cgttttgaag
    45301 tagaaaggga agtataaata ttttgaataa tttataagag ttataaaaag tgaagtctgt
    45361 tgagacttca ttttttgatg caattttaaa attaaatttg atgtttcata atattttaaa
    45421 aactttctac ttttattagt gtgaataact gttgctatta aataataata ctaat
//
LOCUS       DAEPUT010000026        44801 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.026, whole genome shotgun sequence.
ACCESSION   DAEPUT010000026 DAEPUT010000000
VERSION     DAEPUT010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44801
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.026"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            269..1102
                     /locus_tag="KRL22_001578"
     CDS             269..1102
                     /locus_tag="KRL22_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH1272076.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDQMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            1195..2127
                     /locus_tag="KRL22_001579"
     CDS             1195..2127
                     /locus_tag="KRL22_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1272077.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKVTGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            2179..2661
                     /locus_tag="KRL22_001580"
     CDS             2179..2661
                     /locus_tag="KRL22_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1272078.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            2673..3542
                     /locus_tag="KRL22_001581"
     CDS             2673..3542
                     /locus_tag="KRL22_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH1272079.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFVCIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            3585..4340
                     /locus_tag="KRL22_001582"
     CDS             3585..4340
                     /locus_tag="KRL22_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH1272080.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNELLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIKAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            4382..5203
                     /locus_tag="KRL22_001583"
     CDS             4382..5203
                     /locus_tag="KRL22_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory factor"
                     /protein_id="HBH1272081.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            5208..5969
                     /locus_tag="KRL22_001584"
     CDS             5208..5969
                     /locus_tag="KRL22_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBH1272082.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    6130..6387
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6500..6739
                     /locus_tag="KRL22_001585"
     CDS             6500..6739
                     /locus_tag="KRL22_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH1272083.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            7043..8038
                     /gene="ilvC"
                     /locus_tag="KRL22_001586"
     CDS             7043..8038
                     /gene="ilvC"
                     /locus_tag="KRL22_001586"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBH1272084.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VMIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            8091..9779
                     /gene="ilvB"
                     /locus_tag="KRL22_001587"
     CDS             8091..9779
                     /gene="ilvB"
                     /locus_tag="KRL22_001587"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HBH1272085.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKTFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWSAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            9987..10664
                     /locus_tag="KRL22_001588"
     CDS             9987..10664
                     /locus_tag="KRL22_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1272086.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNSVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            10833..12869
                     /locus_tag="KRL22_001589"
     CDS             10833..12869
                     /locus_tag="KRL22_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HBH1272087.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINKNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYRLKDDKISYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(13060..13626)
                     /locus_tag="KRL22_001590"
     CDS             complement(13060..13626)
                     /locus_tag="KRL22_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1272088.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKND"
     gene            13914..14849
                     /locus_tag="KRL22_001591"
     CDS             13914..14849
                     /locus_tag="KRL22_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1272089.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRFKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            15314..16528
                     /locus_tag="KRL22_001592"
     CDS             15314..16528
                     /locus_tag="KRL22_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272090.1"
                     /translation="MQIKIGKVIQRLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHENLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(16947..17468)
                     /locus_tag="KRL22_001593"
     CDS             complement(16947..17468)
                     /locus_tag="KRL22_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1272091.1"
                     /translation="MKFKRLRTSENKLYYKAMELYKISFPFHEQRKSSLQEEILKNKE
                     YQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            17824..18620
                     /locus_tag="KRL22_001594"
                     /pseudo
     CDS             17824..18620
                     /locus_tag="KRL22_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            18730..19320
                     /locus_tag="KRL22_001595"
     CDS             18730..19320
                     /locus_tag="KRL22_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBH1272092.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMMHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            19386..21083
                     /locus_tag="KRL22_001596"
     CDS             19386..21083
                     /locus_tag="KRL22_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH1272093.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIKGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            21297..22136
                     /locus_tag="KRL22_001597"
     CDS             21297..22136
                     /locus_tag="KRL22_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBH1272094.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            22653..24509
                     /locus_tag="KRL22_001598"
     CDS             22653..24509
                     /locus_tag="KRL22_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH1272095.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYSHKREISNELSKKLEIEFSDL"
     misc_binding    24592..24832
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    24898..25133
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            25218..26435
                     /locus_tag="KRL22_001599"
     CDS             25218..26435
                     /locus_tag="KRL22_001599"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH1272096.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            26552..27034
                     /gene="cdeM"
                     /locus_tag="KRL22_001600"
     CDS             26552..27034
                     /gene="cdeM"
                     /locus_tag="KRL22_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HBH1272097.1"
                     /translation="MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSN
                     CGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEK
                     YWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
                     "
     gene            27298..28563
                     /gene="hisD"
                     /locus_tag="KRL22_001601"
     CDS             27298..28563
                     /gene="hisD"
                     /locus_tag="KRL22_001601"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBH1272098.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(28766..29518)
                     /locus_tag="KRL22_001602"
     CDS             complement(28766..29518)
                     /locus_tag="KRL22_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1272099.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYAE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIYIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(29636..29905)
                     /locus_tag="KRL22_001603"
     CDS             complement(29636..29905)
                     /locus_tag="KRL22_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272100.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            30380..31474
                     /locus_tag="KRL22_001604"
     CDS             30380..31474
                     /locus_tag="KRL22_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH1272101.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVDS
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            31476..32426
                     /locus_tag="KRL22_001605"
     CDS             31476..32426
                     /locus_tag="KRL22_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBH1272102.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     RGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVNHG"
     gene            32419..33603
                     /locus_tag="KRL22_001606"
     CDS             32419..33603
                     /locus_tag="KRL22_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272103.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISSYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DVYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            33616..35112
                     /locus_tag="KRL22_001607"
     CDS             33616..35112
                     /locus_tag="KRL22_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH1272104.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            35135..36085
                     /locus_tag="KRL22_001608"
     CDS             35135..36085
                     /locus_tag="KRL22_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272105.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFS
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            36106..37068
                     /locus_tag="KRL22_001609"
     CDS             36106..37068
                     /locus_tag="KRL22_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH1272106.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            37440..38072
                     /locus_tag="KRL22_001610"
     CDS             37440..38072
                     /locus_tag="KRL22_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1272107.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            38483..38575
                     /gene="kdpF"
                     /locus_tag="KRL22_001611"
     CDS             38483..38575
                     /gene="kdpF"
                     /locus_tag="KRL22_001611"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBH1272108.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            38616..40298
                     /gene="kdpA"
                     /locus_tag="KRL22_001612"
     CDS             38616..40298
                     /gene="kdpA"
                     /locus_tag="KRL22_001612"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBH1272109.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            40323..42380
                     /gene="kdpB"
                     /locus_tag="KRL22_001613"
     CDS             40323..42380
                     /gene="kdpB"
                     /locus_tag="KRL22_001613"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBH1272110.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            42399..43025
                     /locus_tag="KRL22_001614"
     CDS             42399..43025
                     /locus_tag="KRL22_001614"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBH1272111.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            43262..44170
                     /gene="cysK"
                     /locus_tag="KRL22_001615"
     CDS             43262..44170
                     /gene="cysK"
                     /locus_tag="KRL22_001615"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBH1272112.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            44197..44787
                     /gene="cysE"
                     /locus_tag="KRL22_001616"
     CDS             44197..44787
                     /gene="cysE"
                     /locus_tag="KRL22_001616"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBH1272113.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
BASE COUNT        17949 a         4500 c         8041 g        14311 t
ORIGIN      
        1 ataaaaaaaa aattataaat tttaaaaatt ataaatgaca ttttaactag aattaattgt
       61 aaaaaacact atataatact caattttcaa cattctatac aattatacag aaattataca
      121 gcataataat caccgaaata acaaatttta aaaattaagc aaaacttttt gtcgaagttc
      181 aacgtctata tatatgtagt gtaaattttt gggataaaat actacaaaaa tataaatgta
      241 aaaatatagt aatattggag gtcgaacgat gagaaataaa aagaaaaaaa taaatagaaa
      301 gaagttgtat ttgcttttaa gtgctattgt agtgtgtctg gcttttatag tagttggtgt
      361 tcgcgtcagc tctttaaata tgaaggaaaa tgaaattagt agaaatgcaa aactgtcaag
      421 ttctactatt acagatatag tatctaatac atcaatagaa gttagtaaag ggccaagtaa
      481 aagttctgga aaaatagcat acataactat agatgatggt ccatctaaat ttactgacca
      541 gatgataaaa actttaaata aatacaatgt taaagcaact ttttttatga tagatgggaa
      601 tatgaaggaa tatccacagc aagttaaaaa tataattaaa aatgggaaca cagcaggttt
      661 tcatagtgta tcacatgata ttcacaagct ttatgttact agtacatcag caaaagagga
      721 atttgataca aatgatcaaa ctttttataa gataactggt aaacattcaa aagtaataag
      781 aataccttat ggaagcaaac catatacacc acaagcctct tatcaggctt tagttgatgc
      841 tggatataaa atttgggact gggacttaga tacagaagac tggagatcta attcttctca
      901 aattgtacaa aatgtaaaaa atcatattaa gaatagaaaa ggtgaagata aagaccaact
      961 tgtagtttta atgcatgaga aaaaacagag tgcagaagct ttagattcag ttttaaaatt
     1021 cttatcagat gaaggttatg aatttgcgcc agtagatcaa aaccaaatac caaaaaatta
     1081 ttggttacgt aatttagagt agttaaaata taagaatatt gattgatatt tttagaaatt
     1141 gagaataaaa atgagtgagg tgtaggtata ttgaataaaa aactttatat aggaatggtc
     1201 ggaatattgt ctttgatgat ggttggttgt aataaaagtt tagcaaaagt aaatgatgtg
     1261 gaaatcacaa aagaacagta caaaaaaaca aaagcagttt tatctgctac taataattat
     1321 ataaatgggc agtctttaga tgaattagaa aaaactttgg ataaaaaagg tagaaataaa
     1381 ttagaaaatg ttataatatc gtttatggtg gataatgaac ttttatatca agaggctaag
     1441 gataaaggac taactccaag taaaagtgaa gtagactcaa aatatcaaga actagaagat
     1501 aagatgaatt tgaatacaag ctataaggaa aaaatggaca aagcaggtgt tgataaagat
     1561 tatttaaaac aagaaatatc tagagattta gcaatagata aaaataaaaa ggcctttgaa
     1621 gatagaataa acataagtga taatgatatg gaagcctact atacaagtca taaaaaagat
     1681 tttaatgtag aagaagtaag tgcttctcag atacttatat cgactttaga taaaaataaa
     1741 aaagaagtaa gcaaagataa aaaagaagct ttgaagaaga aggcagataa tatattgact
     1801 aaaatcaaaa atggagaaag ttttgaaagt ttggctaaaa aatattcgga tgataaagta
     1861 actggaaaaa atggaggaca gctaggatat tttacaaagg atgataaaaa tgctgagttt
     1921 acaaaggaag tgttcaaatt aaagaaaaat gaagtttcaa atgtgtttga aactagttat
     1981 ggatatcata tagtcaaagt tactgataaa agagaaagac aaaaaagttt taatgagtgt
     2041 cagagtttaa taagagaatc tattttaaat gaaaagtata ttgagcatat aaaaaaactg
     2101 aatgaagatg ctaaaataga cagatagaat ttctaacagc tcaatcctag cctgtaatcg
     2161 gagggagatt ttacaggaat gtttaagagt ttaaagagaa cgaaagttga gaaatacatt
     2221 atcgataata aagactcttt ttatagaata gcatatagtt atacgaagaa tgaagaagat
     2281 gccttagatg tggttcaaga agccatgtat aaggcactat actcagtgga aaatattaaa
     2341 gaagtaaatt atataaagac atggttttat aaaattttag ttagaacgag tatagatttt
     2401 attagaaaaa accgtaaata taataatatg acagatattg accttataga tgagactgga
     2461 gagtatgata aatatactga tttggattta agaagagctt tggaagaatt acctattgaa
     2521 tacaaatcta ttataatatt aagatttttt gaagatttaa agattgaaga agtagcaata
     2581 atattggatg aaaatgtgaa tactgttaaa actaggttat atactgcttt aaaaaaacta
     2641 aaattaaaaa ttgaagagta gggataaaaa gaatgacaag caaagaaagg ttaaataagt
     2701 taaaagatga gtatcataaa attccaatac ccaagaaatt agatactata ataaatcatg
     2761 aaaaaataga aaacatatac cgagagaaaa ataaaaaagt aaatagatta agatttaaag
     2821 ttgcaatagc ctttgtatgt atatttacag tattagtaaa tataagtcct gtatttgcag
     2881 acaatttttc taagatacct gtaattggag caatagtaga agtaataact ataaaaaatt
     2941 atagtttaaa aagtgaaaat tatgaagctg agattgatat tcctaaaata cgaggtttaa
     3001 aagataaaaa cttagaacaa agattaaaca gtagttttat ggaagatgga aaaaggcttt
     3061 atcatcaatt ccaagagaga atggagaaga tacaatcatc aaagaataaa ggatataaat
     3121 ctttaagttt gagttatagt gtaaaaaata attctaaaaa atttctatca atagagatga
     3181 caaaaaatga gatagaggct tcgtcatatg tgagtaaagt acattatact attgataaaa
     3241 aaagacaaat agttttgact ttgccaatgc tttttaaaga tgataagtat ataaaagtta
     3301 taagtgataa tataaaagaa caaatgagag aacaaatgaa aaaggatagt acaaaatcct
     3361 attttataga tcaaaaaaaa gacttgcctg ttgaagattt taaaacaatt aataagtatc
     3421 aggattttta ttttaataaa aatgaagacc ttgtaatttg ttttgatgaa tatgaagtag
     3481 cacctggtta tatgggcgca gttgagtttg taataccata taaagtaata aaagatttgt
     3541 aaattgaata gtagtttata tataaatctt ttaaggagga caatatgact acatataaaa
     3601 aacttaaaaa atctatattt aaaattgcta tattttcaat atgcttatta gtttcattag
     3661 tagatacaaa ccctatattt gcaggtagtt cctttaatga aacttcaaat agtgatacga
     3721 taaaggtgtt aaatgctaag agtatcaact ttaaacaaga caattatgaa gtgaatgtga
     3781 gtattcctaa aataaaaggt ttaaaagata aaactttaga gaataaatta aacaatgagc
     3841 ttttgcaaga tgggaaaaaa atttacagtg aatttcaaaa taaaatgaaa aaggaaaata
     3901 ataagggtca tagataccta aatgtaatcc ataatgtcaa aaataattct aaggactttt
     3961 tatcaataga aatgacaaaa gaagagatag aagcttcctc atctataact aagaagcatt
     4021 acactgttga taaaaataga ggaatactat taaatttacc aatatttttt aaagatagta
     4081 gatatattaa agctataagt gataatataa aagagcagat gagaaatcaa attaagaaag
     4141 atgatacaaa atcttatttt atagaccaag ataaagactc cccagtgaaa gattttgaat
     4201 ctataaataa gtatcaagat ttttatttta ataaaaatgg aaatcttgtg attagttttg
     4261 atgaatatga agtagcacct ggttatatgg gagcagtaga atttgtgata ccaaataaag
     4321 taataaaaag actaagatag atatatagaa gatttttaga tagactggta aggagaatta
     4381 tatgaatata tatgaacaag caataagatt aatagaaaat aatgaggatt tcgcatttgc
     4441 tacaataacg tctcattcag gttcaacacc acgtgaaact ggagcaatga tgattgtgaa
     4501 aaatgattct actatatttg gctcagtagg aggaggtagt gtagaagcag aatgtataaa
     4561 acatgcaatt aatgttataa aaaacagaga atcaatgttg tataaattta ctctaaacaa
     4621 atctgatgtg gcaaaactag gaatgatatg tggaggtact ggagaaatac aaatagattt
     4681 tatagatagt aaattaaaaa gtaatataga aaaatttaat aagagactaa aggaaaatac
     4741 aagtaaagca tatatatttg gtgcaggtca tatttcaaga gatgttgctg tgatactatc
     4801 tcttttagaa tttagaacag tagtaataga tgatagagaa gaatttgcta atcatgaaag
     4861 gtttccagaa tcagaagtag tagttttaga ttcttttgaa aacataccag attttcccac
     4921 tgacgaaaat agttatataa ttattttaac aagaggtcat ctatatgatt caagtgcttt
     4981 agaatgggct cttaaaagag aggctggtta tataggtatg attggaagta gaacaaaaat
     5041 tggattgact tacgaaaaac tcatgaaaaa aggttttaag aaggaagaat tatcaaaagt
     5101 acatgcacca ataggcataa aattgaatgc tcaaacacca gctgaaatag ctgtatgtat
     5161 agctgctgaa cttataaatt gtagagccaa taaggaaaaa taaactaatg aacacaggga
     5221 gtaaagatat tgatacttta aaggttaatt ttagagggat tgaaataaaa gcagttttag
     5281 tatataaaaa tagaaaaaat atttctataa aaatagatcc atttggcaaa ataactgtaa
     5341 tgagtcctcc taaaatatcc aaaaaaataa taaaagatat aattattgaa aaaggagact
     5401 ggatacttaa aaagtcagaa aaatgtaaag gaagagagga agtatataaa caaagaatgt
     5461 ttataactgg cgaaaaattt ctttatttag gtgaagaata ccatctagtt ataaaagaac
     5521 tgttgagaga ttctgtcaaa aaaagtaact gtagaataac tattaacgaa tatcaaatag
     5581 ttgttcagac aaatgataca agtacagatt ttattaaaaa atctttaaaa tcttggtata
     5641 agatggaaag tgaaagaata gtattagaga gaatagattt tcttaaatta aattgtgaaa
     5701 taatgaagca attagttcca gcgagtgtta aggtaaaaga acaaaataag agatggggaa
     5761 gttgtacagc tcaaaaaaat atttatataa actcaaaaat atctatggca agattagatg
     5821 taattgatta tgtaataata catgagttta gccatttagt acatatgaat cactctaaaa
     5881 aattctatga tttagtaaaa tccattatgc ccgattataa agataaagaa aattggctaa
     5941 aaataaatgg atataaaata ataatctgaa aacgattatt ccaaaatata ggcataaagt
     6001 ataaaagaag tattattgtg aaaaaaataa ataatctgaa aattttaaaa aaagtcattg
     6061 acattgtaaa tgatagggaa tataatctat attaacaaca aaacagaatt aaaatataaa
     6121 attaaaaaat taaaagcaat gacagagaca acaatactaa tagtgttatc cacagagaac
     6181 caatgttgct gagaattggt gttaacagta gtataatgat cactctggag cttttgtact
     6241 gaatattttt agtaagtaca aacgtatgtc aacgttacat ggctaaggtt aaggtaatta
     6301 attacccgac ctgaaaaaag aggggtagat gtatttttta tatctacaaa taaggtggta
     6361 ccgcggaata taactttcgt ccttataagt aatatttata ttgcttataa agatgaaagt
     6421 ttttttattt taagcgatat aaataaattt aatccatata aaattaataa aaaaataata
     6481 aaaataagga gggattttta tggaaaatac tgtatatgct aaattaaacc aaggaataga
     6541 ttctttttta agagtggcta tgactctaag aagaagagag gttgatatac aatcaataag
     6601 tatgactgta gataatatga ataattcagg tataaaatta atagtaaatg aagaaaagac
     6661 atctttagat tctgtcttaa accatatgaa aaaactacat gatataagag agataactgt
     6721 tgaaagaatg agacattaat taaatatatt ttataaaact aaagataaat atgcttattt
     6781 taaaataaaa aactaaagat aaatattaaa taagaaaaat cttagattaa aatataagtg
     6841 tcattgaatt tattagttta tcacagttaa taaatttatt agtttgttgt agctaataaa
     6901 aactgaaaat tctaaaatta taattgtaag attatataaa tttagaattt aaatctgttg
     6961 aataatatta aaacaatgat aatgagtatg aatttctaat aaaaataaat atcataaaaa
     7021 taagaaaaag tattgggagg aaatgaaaat ggcaagaatg tattatgaaa aagatgtgga
     7081 tttagaggtt ttaaaaaata aaaaggttgc agttttaggt tatggaagtc aaggacatgc
     7141 acatgcacaa aatcttagag ataacggtgt acatgtaatg ataggtcttt atgacggaag
     7201 taaatcagca caaaaagcaa aagaagatgg atttgaagtt aagagtgtag cagaagctac
     7261 aaaagaaagt gatttgacaa tgatgttaat gcctgatgaa aaacaaaaga aagtttatga
     7321 agagagtgta aaggataact taaaagaagg tcagacatta gcttttgctc atggattcaa
     7381 tatacattat aatcaagtac aaccaccaga atttgttgat gttgtaatgg tagctcctaa
     7441 aggacctggt cacttagtta gaaatgtatt tacaaaggga agtggagttc ctgcactatt
     7501 tgcagtatat caagactaca ctaaaaaagc tacagagaca gttttagcat atgcaaaagg
     7561 gataggagca acaagagcag gtgttttaga aactactttt aaagaagaaa cagaaacaga
     7621 tttatttgga gaacaatcag tactttgtgg tggaataagt gaacttataa aattgggata
     7681 taaaacgctt gtagatgcag gttatcaaaa agaagtagca tattttgaat gtttacatga
     7741 aatgaaacta atagtcgacc ttatatatga aggtggattt gaaagaatga gatatagtat
     7801 aagtgacaca gcagaatatg gagattatgt atctggtaaa agggtaataa ctgatgctgc
     7861 aaaacaaggt atgcaaaatg ttttagagga tatacaaaat ggaaaatttg caaaagcgtg
     7921 gattaaagaa aatgaagaag gacgtgaaaa cttcctaaaa actagagaag aagaatataa
     7981 tacagaaatt gccgaagttg gtagaaatct aagaagtatg atgtcattct taaaataaat
     8041 atatattaaa tggattagtt tgagggaaag agtggtgtat agtagtgcgt atgaatggag
     8101 caaaggtaat tttagaatgt ttaaagaaag agggaattga cacaatattt ggatatcctg
     8161 gtggagctgt gatacctctt tatgatgctc tatacgatta ttcagatgat tttaaacata
     8221 taaggacatc ccatgaacaa ggtttagttc atgctgcaga tgggtacgca agaagtacta
     8281 atacagtagg agtttgtttt acaacatctg gtccaggagc aacaaatgcc ataactggaa
     8341 tagcaacagc ttttatggat tcttcaccta tggttgtaat ttcagggcag gtgccaacta
     8401 gtttattagg aaaagattct tttcaagaaa ttgacataac tggagcaaca ttatctatga
     8461 caaaacataa ttatttagtt agaaacacta aagaattagt tcctacaata aaagaagctt
     8521 ttagagttgc aaattcaggt agaaaaggac ctgtacttgt agatgttcca aaagatttat
     8581 ttttagcaga aatggatttt agtggtgagg actatgattt atgtcaaata gatgattata
     8641 tggattataa gagtgatttt gatctagatg atgaaactaa tattaagctt ttaaatgaag
     8701 caatagatat cataaaagaa tctaaaaagc ctgtaatata tgcaggtgga ggtgttaaat
     8761 cttcagacag tgaggaaatt cttgaaaaat ttgcaactaa gatagataca cccgtactaa
     8821 atacacttat ggggcttgga aatatagata gaaagaatga actatctctt ggaatggttg
     8881 gaatgcatgg aagtagagaa agtaatttag cactttctaa ttcagattta gtgatagcga
     8941 taggtgcgag atttagtgat agagtgataa gtaaaagttc tgaatttgct aaaaatgcaa
     9001 aaataataca catagacata gacccatctg aaataagtaa aaatatagaa tctaatgtat
     9061 ctttggttgg agatgtaaag ctagtcctta gtttattaat tgaaagggtt gaaagtaaga
     9121 ataatagcaa ttggaaagaa gagataaaga catttagaaa gagtgagggt gtacaaacat
     9181 atgaatttca tccacaaaat atacttaaaa aaataaatga aaaatatgaa acattaaaga
     9241 aacccactgt ggtagtaact gatgtcggtc aacatcaaat gtggtctgct aaatactgga
     9301 attttaaagg taataaaagt tttataacat cagcagggtt aggaactatg ggatttggtt
     9361 taggtgcagc tattggaact aaagttggta atgtagataa aaatgtagtt ttagtcactg
     9421 gtgatggaag ttttagaatg aactgtaatg aactagctac agttgcaaat tataatgtac
     9481 ctatgcttat tttactactc aataatagaa cattaggaat ggtaaggcaa tggcaaaagt
     9541 tattttccaa tcaaagatac tctcaaactg acattaatga aaatgtggat tatgttaaac
     9601 tcgtaaatgc atataatatt gatggatata aggtatccag tatggaagaa ttaggaaagg
     9661 cactagatat gatagatttt aataaacctg tatttttgca atgtgatata gataaggatt
     9721 atgatgttta tcctattgta gcacctaatg atgcattgga aaatttgata tgtaactaaa
     9781 acttatactg aatattgata aaatttttta ttaaattttt attggtattc aggttttgtt
     9841 tagagataga ttggcatttt ttatttttgc aaataaatca atgactatat aattaagaac
     9901 ttattaaatt ttaattatac aatttagaat agtattacaa cttaagtaaa taataatttt
     9961 gaataataat ttacggaggt attcatatgt ttaaacacga taaagcatta ttaaaagaag
    10021 taaaagtaga aagaccaaat cctcaatatg ctgttttaat gcaagaacag ttgggtggtg
    10081 caaatggaga gttaaaagca gctatgcaat acttgtccca aagttttaga ataaaagacc
    10141 ctcaaataaa agatttattt cttgatatag cagcagaaga gcttagccat atggaaatgg
    10201 tagcacaaac tataaattta ttaaatggac atgatgttga ttataattca gttaatacag
    10261 gcgaaataga aacacatgta ttaactggtc tatcaccagt cttaataaac tcatcaggag
    10321 ctccttggac tgctaattac gttacagtta caggggattt agtagctgac ttactttcaa
    10381 atatagcttc tgaacaaaga gctaaggtag tttatgagta cttgtataga caaatagatg
    10441 ataaatatgt aaaagaaaca atagatttct tacttaatag agaagaagca cataatgctc
    10501 tatttagaga tgctttaaat aaagttaaag atacaggttc aaatagagat tttggagtta
    10561 cagaagattc taaattatat ttcgatttgt ctactccagg gccaaatcac gatactaaga
    10621 tagatattaa tcctccttct tttgaaaaac ctttaaaaaa ataatttgat attttttatt
    10681 ttgttttagt agttataaaa attatttact agaagaatta attatatgaa aaattaaata
    10741 tgtatagtta aaaatgggta tacacttatt ataagtgtat atctatttgt ttattgcaaa
    10801 acatataata aaataacaaa tgaggtggta ttttggacag taatagaaaa cctaataatc
    10861 taataaatga aaaatctcca tatcttttac agcatgctta taatcccata aactggtata
    10921 gttggaatga tgaggctttt aaaaaagcaa aagaagagga taaaccaata tttttaagtg
    10981 taggatattc aacatgtcat tggtgccatg ttatggaaaa agaatctttt gaagatgaag
    11041 aagttgctga aataatgaat agaaactttg tggcaataaa agtagataaa gaggaaagac
    11101 ctgatgtaga tagtgtgtat atgacagttt gccaagctat gacaggtagt ggtggatggc
    11161 caatgaccat aataatgaca ccagataaaa aacctttttt tgcgggaaca tatttcccaa
    11221 aatattcaag gtataataga cctggagtta tagatttatt agagaatgta tctgaaaagt
    11281 ggaatacaag cagggatata ttaataaaat ctggagatga aataatagaa gctcttaagg
    11341 atgattttgg tgtaaaaaat actgagggtg atttatcaaa agagatgttg agttcatcag
    11401 ttagagtatt taaggctatt tatgatgaaa agtatggtgg ttttggtaat gctcctaaat
    11461 ttccaagtcc tcagaatctt atgtttttaa tgaaatatta tagtatagaa aaagacaaag
    11521 atgtgttaaa aatggtggaa aaaactttag atggaatgta tagaggaggc ttgtttgatc
    11581 atattggatt tgggttttca agatactcta ctgataaaaa gtggttggct cctcattttg
    11641 aaaaaatgct atatgataat gctatgctta ctatagcttt tttagatgcg tataaaataa
    11701 caaagaaaga gttgtataaa gaaattgcta taaaaactat agattatgta gttagagaga
    11761 tgaaggataa agaaggtggg ttttattcag cacaggatgc tgatagtgaa ggtgaagaag
    11821 gtaaatttta tacatttaat cctcttgaga taattgaagt tttgggtgaa gaggatggaa
    11881 ctttctttaa taattatttt gatataacta gtagtggaaa ttttgaaggc aaaagtattc
    11941 ctaatctcat aaaaaataaa gaatatgaaa gacataatga aaagatagct gaccttagta
    12001 aaaaggtatt tgaatataga aaagaaagaa catctttgca taaagatgac aagatactta
    12061 catcatggaa tgcattgatg atagttgctt taacaaaggc atatagtact ttaaaaaatg
    12121 acatatattt agagtattca aataagtgtc ttaactttat aaataagaat cttgtaaatg
    12181 agtcaggtag attattagct agatatagag atggaagttc cgactattta gcatatttag
    12241 atgattatgc ttttttaatc tgggcgtata tagagcttta tgagtcaaca tttaatatga
    12301 aatatttaga aaaggcttta aatttgaatg aaagctgtat caaccttttt tgggattatg
    12361 aaaaaagtgg attttatata tatggtaaag atagtgaaaa tttaatagca agaccaaaag
    12421 atttgtatga tggagctatt ccatcaggaa attctgttca attatacaat cttataagac
    12481 ttgcgaaaat tactggagat aatagacttg aagaaatgtc atataaacaa ttaaaactgt
    12541 atgtggataa tgtaaagagt tctccaactg gctacagctt ttatatgctt tcattgatgt
    12601 ttgaacttta ttctactaag gaaattatat gtatttttaa ggaagattct gatttaattg
    12661 catttaaaga attgataagt gaaaatttta taccaaatgc aactttttta gcaaagaaat
    12721 acaatgaaga aaacactatt ataggttttt taaataacta tagattgaag gatgataaga
    12781 ttagttatta cgtgtgtcaa agtaatagtt gtagtcaacc aattaatgat ttacaaaaat
    12841 taaaagatat gattttagga gtagaataat cataatagtg aaaaaggaga tgctttaaaa
    12901 taaaagtcta atcatctcct ttttttgtac aaaaaacaga aaaagagttc ctgagaacac
    12961 ctaatctatg taatgattgt tttgttaaaa aataaaaatg acattatagt tatataaaat
    13021 attgtactac aaaaaagtag tattatagat gcgatagtat taatcgtttt tatttactct
    13081 atttcttctt tttgcaaatt cttcaagtgc ttcagattta attttatcta tttcttcata
    13141 ttccataaaa ttagcatctt cttcaaagcc atcttgttct tcaccattaa aacgatacat
    13201 tttttttagt aaactccata aggtctctaa ttcatctttg gtaaattcgt gaaatacatc
    13261 tgccataaag tttattccag tcctactaca tgtcaccata accttttttc ctaagtctgt
    13321 aactttaaca ttaattgctc tcttatcatg aggacttgga attacatcaa catatccatt
    13381 tttttcaaga ttagcaacta gtctatttat attttgttta cttgtaccca tttttcttgc
    13441 aatattattt aatgttgttt cttcctctgg taaatgaaga attgataaaa tagtcatata
    13501 ctgtcttgaa gtaagtatac caaaatattt atctccttct atttgtattt tgtttgtaag
    13561 ggtaaaaaga gttgcatatg tttgattcat taaaaagagc tcttttagtt catttgaata
    13621 atccatgaaa tatatctcct ttatttttag aagttgtttt gtcgaaaaca gaatatcatg
    13681 aattaattct aatgtcaata tggtgtcaaa atatattaaa gtattacttt tttatgtaac
    13741 tattaattaa ttaaattatt gtataatttt atgtaaaaac ttctatgtac caatgataat
    13801 ttctatgagg aattaataat tcttaaattt tttagaaaga ttttgacttg aaaatacttg
    13861 taatataata tataaattaa tatactgaat aaaatcaatc tggagggata attatgaagt
    13921 gtacaaactt tactttcaaa ggagaggaag gtttagatat atatacatat aaatgggaag
    13981 atgaaaatat aaaaaaacca aaggcagtta tccaaattgc acatggaatg gctgaaactg
    14041 cacaaaggta tgagactttt gccaaggtac ttactaaaaa tggttatata gtatatatca
    14101 atgaccatag aggtcatgga aaaactgcaa agataataga aaatgttgga catttagctg
    14161 aaaaagaagg atttagatgt cttgtagagg acatgtatac tttaacaaat attataaaga
    14221 aagaaaatga agatttgcca atttatctat ttggacatag catgggttca tttgcaagtc
    14281 aaagatatat aatggattac agtaataatt tatctggact tatactatgt ggttcaaatg
    14341 gaaagcaagg aatcattcta aatcttgctc atctgataat caatcgtgag attaaaaagt
    14401 atggaagacg ttttaaaagt aataaaataa ataatttgat atttggcggc gaaataataa
    14461 gaagaaatga aaagactaag tttgactggt taagtagaga taaagaacaa gttgaaaaat
    14521 atataaatga cccattttgt ggagtagtgt gtagttgtgg ctttttttat gatttagttc
    14581 aagggttaaa agaaattgag gataaagaaa acttaaaaaa agtgccactt gatataccta
    14641 tttacataat atctggagat aaagacccca taggaaaaaa tggtaaagga gtcttaagac
    14701 taagggatag atatataaaa ttaggagtaa aagatgtaac ttgcaaactt tacaaagatg
    14761 gaaggcatga attgttgaat gaaataaata gagaagaagt ttttgaggat ataatttgtt
    14821 ggttaaataa taaaatagaa atattgtaat aaaaaaatat aatgatatat ttactttaaa
    14881 tttatttata tataatattt gaaaagtgga ttatgtatat gcaaagtaga aaagagagag
    14941 cctagaagtg atttttcgct ataatgccat ttattgaata ggtgggtgtt attataaata
    15001 aattattaac actcagtatt attatcattg tatatggaat ttattttatt taaaattcct
    15061 tgaaagttta aatatagtaa gttgtaataa agagaaaatc taaatattta aatgctattt
    15121 aatgtgaatc tattaattag gttatactta aacttaatta atagatttta tatttcaaga
    15181 caatgagata gggttttaga ttaaaatata accaatggtt aaattacaga cattttgtta
    15241 actttccctc gatttactag taaatatttt tttaatatac ttaaattaca acagatgtac
    15301 tagggaggta tatatgcaaa ttaaaatagg taaagtcata cagcgtctta gaaaagaacg
    15361 aaatttaact caagaacaat tagcaaagtt tataggtgtg tcaacaccag cagtatctaa
    15421 gtgggagagt ggaaattctt acccagatat agaattattg cctttattag cagacttttt
    15481 taatgtgtct attgataagc ttttaaatta caagattgat ttaagtgaag aagaagtaat
    15541 gaaaatttat aaagaattag aatcaggctt tgctagaatt gaaattgatt tatcaacaga
    15601 agaaccaaaa gaagaattta gacaagactt agaatctgta aaaaagcttt ccaatatgta
    15661 tatagagaag tatcctaaaa gctatttatt gaagctaagg atatgttcgc tgtatcagat
    15721 gtattcatat aaatttggta agagtgaact taatgacaga gtaaaagaaa caacgaatat
    15781 tcttgaagat atagtgagaa atacagatga tatccaaata aaagaaacag ctcttattat
    15841 attatcaaac gcatattgta tgttggagga ttatgaaaag gcagagttgt atttaaatat
    15901 gatacataag tcaatagggg atacaagtgt taatttagct atgatatatt taaagcaaaa
    15961 tagacttgaa gaagcagaaa tattgcttca aaataaattg tttagtaatg tatttaatat
    16021 aagcatggat tgtaagggaa taattaatgt atacaaaaat caatacaagg aattaaagaa
    16081 aaaattggag aatagaaatt ttaataaaaa tgcaattgag agagaaatgg agtatataaa
    16141 aaataagttg ctggggtatg caaatctttc tttagaaata aaaaaaatgc tcagtgaaga
    16201 taaaggtgca ttttttagta tgtatatgga ttatatggaa ttatctctaa tttttttatt
    16261 ttttaacatg aaagaagaag caaaaaaagc cttatatagt ctaaaagaaa tattagaaaa
    16321 atatcctata catgaaaatt tggatgtaag tcaaatgaga ttttttgata aggtagagtc
    16381 taaaaattta tatactttta atatatatac aaacttgtta attgtactta atgatgatag
    16441 ttataatgag cttagagaag aaccaatttt taaggatgta attgaaaaga ttttagatat
    16501 ggaaaaaatg ttgaaaaata aagaataagt aaaaatttaa tataggactt aaagattaat
    16561 caaattaaaa gaaagtgttt caaaataaaa atttgaatca ccttttttgt ctgtcttaaa
    16621 cagttattta gaaaaataga ggtttcaaaa tagaaatctg aattatctgt attattacac
    16681 aaaaatagaa acctaaattt ataaaaatag aataaagttt gttatataaa atgtaatttt
    16741 gtctataaaa tctcacctgt tttctaactt taagcgtgaa aaagagaatg tatcatgaat
    16801 tttttagttc atgatgcatc cttctttgta tgaaatccaa tatatcttta ttatttaaac
    16861 aatggaaaag agtcttattt ctattttgag acatctcttt tatttaatta tgaagtttta
    16921 tacagttcaa taaataggaa ttatatttag aaactcataa cattatttct tagatagtga
    16981 ttaaatttat catattccat tttagataac ttttctgggt aagacattac aatcaggtta
    17041 tgcccattaa atttttcatg gtatggtgga tgaatgtgtt cataattatt tgtcttatat
    17101 tttactcttt catagaacgc cttgcgataa attgaaatct catcaattgg aaggtcaatt
    17161 tctaaaataa tagtttttcc tttcttattt aaaagctcta acgctctttg tccatatcta
    17221 ttattgcgca tttctggaaa aatgcagaaa tgttctacat agataaagtc atctgtttcc
    17281 caacataaaa ttatgccgac aaactggttt ttatcataaa ttaaattgaa ttgatattct
    17341 ttatttttca aaatttcttc ttgcaaagaa gattttcttt gttcatgaaa tgggaaacta
    17401 attttatata attccatagc cttgtaatat aatttatttt cactggttct taaccgttta
    17461 aatttcactt tactcctcct aatcactaaa attccaattt atttatgagt tcattttacc
    17521 atagtcagta tttgcataca atgtgtttta agttgagtgt catttctttc ttttatttat
    17581 gtttatatct catagactaa gagataattg cttaagacat aactaaaaac tattatatta
    17641 agctttgata atctaaaaac agtatattta tggacttttc taggtctaaa agtaatctta
    17701 ataattttag aagttacaaa aaagttacat aaatttggaa agctataata tacatatata
    17761 atataaggtt aaaactgtaa tgaataatat taatttaaaa tttgaacatg gaaggagatt
    17821 attatggaga aaagagaaaa gaggataata atatcatctt tattaagtgt atcaatttta
    17881 atgggtttga caagtatata ttctatatta aataaagaag acataatttt aactgttaag
    17941 ggtcaagagc aaaaagtatc ttcctttaag aaaacagttg aggaactttt ggatgaacag
    18001 ggtgtaaagt ataattctga agataagatt aatccaagtt tagatacaga actaaaagat
    18061 gatatgaaaa taaaagttgt taaggtaact aaaagtaaaa aagaagagat tgaaaaaatt
    18121 ccatttgata caaagcatgt aaatgatagt aatttgttaa aaggaaaatc taaagtttat
    18181 caagaaggtc aagaaggaga aaaaaactag tctataattt aacttaccat gatggaaagt
    18241 tagtcaaaaa agtcttatca aaagaagtaa tatctaagga gccaactaca aaaattataa
    18301 aatatggaac taaagaaaaa gtactaatag catcaagagg agcaaatata agaggaggca
    18361 aacatatgaa agtggttgcc actgcatatg caggagatac aataacatct actggtacaa
    18421 ctccaagatg gggtgttatt gcagttgacc cacgtgtaat accatatgga acaaaagtat
    18481 atatacctaa actgggtatg acttttgtag cagaagattg tggaggtgca attaaaggta
    18541 atagaataga catttttatg aacagtgaag gaaaagcttc aaattgggga aggaaaagta
    18601 tagatatata tctacattaa attagtgaat agaataactt tacttgaagg acaaaaaagt
    18661 ataaaatatg aattaactaa actgttagat tattcttaaa acataaaaat atatctaagg
    18721 ggggataaga tgaaaatagt ctgcttagga gacagtttaa cgtatggatt tggagtatca
    18781 cgaagtaatt catggacaaa cattgtaaat aaagagactc gattagaaat agtaaataag
    18841 ggtataaatg gtgatacaac aagtggtatg ttagctaggt ttaatgaaga tgttgtaaaa
    18901 aattctcctg atatagtttt tataatgggt ggcaccaatg attttattgc tggtgcggga
    18961 aatgaaatta ttaattctaa tataatggct atgatgcatc agtcatattc aaaaaatatt
    19021 atacctataa taggtatacc attaaaacca gatattccaa atgttaggga agattggagt
    19081 tgttttactg attttaatat agtatctcaa aacttagaat catatagtta ttggataaaa
    19141 aaattttgta tgacatttaa tactaatttc gtagattttt attcagaata taataaaaat
    19201 atggaactag aaggatataa aaaattatat tttgatgggt tacatccaac caaagagggt
    19261 catagaataa tggcagacat ttttattaat tcaattaata agtatataga agagttatag
    19321 attacattaa aatgcttgtt tatgcgtcag ttgcaataaa tacatacagt agagaggggt
    19381 ttattatgga ttatactaaa acttatgaag agtggataaa gggttcatat tttgatgaag
    19441 atacaaagct agagttggag aatataaaaa ataatgaaaa agaaatagag gatagattct
    19501 ataaggattt agaatttggg actgcgggtc ttagaggaat aattgaagca ggaacgaata
    19561 gaataaataa gtacacagtt agaagagcta cttttggatt ggcaaactat atattagaaa
    19621 acacaacaaa agaagaaaca agtagaggag tagtaatagc tcatgataat agacacaagt
    19681 ctagacaatt ctgtatagaa tctgcaaata ctttggcagc atgtggtata aaagcatata
    19741 tatttgatag tttgagaact actccagaat tatcttttgc tgttagaagc ttaaatgcaa
    19801 tcgctggtat agtcataaca gcaagccata atcctccaga atataatgga tataaggtat
    19861 actgggaaga tggagcacaa gttatgccag agattgcaaa tgcaataaca gagaaagtaa
    19921 atagtataca tgattatagt acaataccaa ccttaacgga agctaataaa aatttggtag
    19981 ttttgttgga cgaatcacaa gatactaaat ttatagaagc agtaaaaagc caaattataa
    20041 gaaaagattt agttaaaaat gtaggtaaaa gctttaagat agtttataca cctctttgtg
    20101 gaacagggaa tgttccaata agaagagcat tgaaagaagt tggttttgaa aatataattg
    20161 tagttccaga agaagaaaat ccagacccaa attttgcagg gcttgattat ccaaatccag
    20221 aagagaaaaa agctttaaat agaggtatat tactcgcaaa agaaaaagga gcagaccttg
    20281 taatagcaac tgacccagat tgtgatagag taggtgtagc agtaaaaact actacaggtg
    20341 agtatgcttt acttacagga aatcaaattg gtggtatgct gacacattat ataataaaag
    20401 gattaaaaga aaataacaaa ttaaaagaaa atcctacaat aataaaaacc atagttacat
    20461 cagaatttgg agcagatata gctaaagcaa ataatgttga tgtattaaat gttcttacag
    20521 gttttaaatt tattggtgaa aaaataaaat tatttgaaca aaataaaaat agaagttatg
    20581 tatttggata tgaagaaagt tatggttact tagttgggac tcatgctaga gataaagatg
    20641 gtgtagtttc ttcattgtta atatctgaaa tggcagcatt ttactattca aaaggtatga
    20701 gtttatatga tggtttaata gaactttata aaaagtatgg atttttcaaa gaacagacta
    20761 tatctttgac tttaaaaggt atagaaggtg tagaaaagat aaaagaaata atatcttatt
    20821 ttagagaaaa tcaaattgat tatataaata gtattaaagt agttgataaa aaagattata
    20881 aaaatggtat agataatctt cctaaatctg atgttttaaa atactttttg gaagatgaat
    20941 cttgggtagc tataagacca tctggaacag aaccaaaact taaattttac atagctgtaa
    21001 aaggagctag tgatattgaa gcagataaaa agattcaagg tttgaaaaag tatatagatg
    21061 acatggtcga aaaattaaaa taaaatatta ttattttata agataatttt gtaataatat
    21121 ttatttagct gaaaattata atttactttc attgagtaga atatggaaat gttagtagaa
    21181 ttgttatttt cagcttttat ttgtgttatt tttacttaaa taattatatt atagaatgaa
    21241 tctgagtata attaatattg tataatgaaa ttaatttgat agaaaagggg atatttatgt
    21301 ttggtataga taagaaattg attgaatata taattgcaaa atccaattac agtgaattaa
    21361 gttcaaagtc agcagaagta tctttcttct taatgttgtc catatttcct tttttaatat
    21421 ttacaataag ttctatagct tatataccga ttcttcattt aaataagtat atagctttgt
    21481 ttagaaatat gatgccagaa ggtgcttttg ctgtgttatc ttcaatcata gtttctgcaa
    21541 tagacaatag aaacctgaaa tttttagcag tcagttttgt acttactatg tggacatttt
    21601 caagagcagt aaaagctctt attaaaggaa tgaatagagc ctataaagtt aaagaaacta
    21661 ggtctttttt taaaatttta tctatatcat ttttatttac aataatgctt ttggtcctta
    21721 tttttttatc tatgatattt ttagtttacg gggaaaaaat aggttatttt atttttaatc
    21781 ttgtaggatt ggatgagata tttataaaaa tatgggatat tctaagatac actgtaggta
    21841 taataacaat aatagtgata tttacacttt tatataaata cactccaaat aaaaagttaa
    21901 ctattaaaga atctgcgcca ggtgctattt ttgctacttt tgcttggttt ttagtatcat
    21961 ttttatattc ttattataca aattactatg ctaactatga agtaatctat ggaagtatag
    22021 ctgaaataat tgtacttatg acctggatgt attttagtag ttggtctatc gttattggct
    22081 atgaggtaaa ttcaagattg tattttagaa agataagaca tgaaatgtta aagtaaagta
    22141 tttaaaataa aagagagtat ttagtattat aaatgtaatt gaattaataa agaaatattg
    22201 acatttaagt taaaaagtct agaatttttc tgggcttttt ttatttttag tataacttga
    22261 caaattttat ttaatgggat agttttaatt tataatcatc tttaaaaaga tgactattga
    22321 taagtaagag ataaaattgg taagtatcaa aaaatatact aaataaaaat tatagtccta
    22381 atgagttaat ttctgtattt tcaaataatg cagtatttag tcatgtgttt ttatatgtgc
    22441 ctgtatttct aattaccaat atattagaat aagctactgt aattaggttt agaaaaaagc
    22501 gacataaata attataaaca aataataaat tacataaaat taaatttatt cacaagtata
    22561 tcttataaaa tatgttataa ttaatagaaa attgtcatat aattaattaa gtagtattat
    22621 tataaataac attgaaaggt agtggttaga atatggatac ccataataaa tatgtaaatt
    22681 ttataaaaaa tatacctgta ccttttttat attgtagaat tgtaaagaga caagaagata
    22741 tagaatatcg agtagaatat ataagtaagg gtatgggcaa agtattacaa ttagaagaag
    22801 gtatttgtga taaaaatata ttagatgtat tgcctgtatt taagtctaaa aaatatttca
    22861 aagagttgtt ctcaaatgaa gtggattgta taaaaaggta cattccgaca cttaaaaact
    22921 ggataaatat aaaaaaacag ataatagggg attcatacat aattttgtat tttggtaaaa
    22981 ttgtatttga ttatagacag ataatcgatt cctttgataa aaaggaaaaa gtagcttata
    23041 ttaaagacga agaaggcata tatatagatt gcagtgaaaa tttaatacca atattaaata
    23101 acaacattaa aacaacgaaa gatatctttg gtaaaaatga tatagaagta tggggagaga
    23161 atacaggaaa attatttaga gatgattata gagaaggagt atctagtaaa aaaagatttt
    23221 tacaaaatct ttttgaatat gaagaaacat tttttatggt tgaaaaatat tttttgtatg
    23281 atgaagacga acttttaggt actataggga tagtagacaa tataatatat agtggttaca
    23341 gtaatagaaa ttataactca aaagatttaa tgaagatgat agaacactca attccagaga
    23401 atatgtttta taaagatgtg tatggaaatt atattggatt taattcaggt tttttgaatt
    23461 tagcttgtat gaataaagaa gaattattag ggaagaatag ttataaaata tcagaagaag
    23521 aagctttaat agataagata tttgaaagtg ataagggtgt agttgaaaat aaaaaagtag
    23581 ttacatttga gttaaatata agtatgaatg atgaaaacaa gtgtattgag attacaaaaa
    23641 ggccgttttt tgatagctat ggaagtgtta ttggaataat tggaacagca agggatataa
    23701 gtagaagaaa aagattagaa gaggaaatgg ataaaactag gatggaattt tttgcaaatt
    23761 tatcccatga acttagaacg cctataaatt taatatcatc ttcattacaa gtgatagaaa
    23821 aaaaagaagc agatttaata gaatcaaatg atactttaaa aagaaatcta ggtataataa
    23881 aacaaaatgg aaatagaata ttgaggttag taaataatgt tatagacttt acaaaaatgc
    23941 aatcaggata tttagatttt aaaccagaag aatctgatat aattgcattt atagaggaga
    24001 tatgtatgtc tgtagctgat tttgcaagcc aaaataatat acaacttaca tttgatacag
    24061 aaatagaaga attttcaatg ttatttgatt cagaaaaatt ggaaagaata atattaaatt
    24121 tactttctaa tggaattaag tacaataaga aagatggaaa aataaatata tttttatatg
    24181 tgaaagataa tgtatttaat atgaaaatat ctgatagtgg tataggtata ccaaaagaaa
    24241 aaatagataa aatatttaat aggtttgaac agattgacaa tgaactttct tacagagtta
    24301 aaggaagtgg tattggactt tcattagtga aatctttggt tgagttgcat gagggaagta
    24361 tatctttaaa aagtcaactt ggtattggaa gtgaatttat agtttcattg cctgttagaa
    24421 gtaaaaataa tattgaaaaa tatagtcata aaagagaaat cagcaatgaa ctaagtaaaa
    24481 aattagaaat agagttctcg gatttataag tttaaatata aaaaataaaa ttttaaaaaa
    24541 gtattgacaa ttgatttaga agggtttaaa ataaattaca acataataaa taaaaaggcg
    24601 atgaatagga agagtaaatc taattcgatt accagagaga agagtccgtt ggctggaaga
    24661 ctttttaaat tagagggatt gaaaactacc taggagctac tttctgaagt catctgcatt
    24721 agtagatttt agtaagaata gtcgttagct gcgttaaagt gtaaagtgag ttttcatgac
    24781 atatgaaaac taaattaggt ggaaccgcgg gaataatact ctcgtcctta tgttataagg
    24841 atgagagttt tttgttattt aaaaatataa acagtaatca taataattat agaaaatata
    24901 aaagcaatga ataggaagag taaatttaat tcgactatca gagaggaaag ttcacaggct
    24961 gaaagacttt ctaagtttga gaaattgaaa actacctagg agctgtggtc tgaagttact
    25021 ttaaaaagtt ttagtaagac taaccgttaa ctgcgttaaa gtgtaaagtg gattttatca
    25081 ataaatgata aaatcaaatt gggtggaacc gcgagtatgg actcgtccct ttatataggg
    25141 atgagtctat ttttattgca ataaaagatt gaaaataaaa aaaaatcgga aaattataaa
    25201 tttaggagga aaataaaatg gagaataaag tgaaaattgg agtactagga tatggagttg
    25261 taggaagtgg acttatagat ataatagata ataataaaga aaaaagaaat atagaaatag
    25321 ttggaatttt agttaataat ttggaaaaac ataaggacaa aaaatattct aatataataa
    25381 ctaataatat agatgatata tttaataaag atatagatat acttgttgaa gtcatgggtg
    25441 gtttagaacc atcattatct tatataaaaa aagcattaaa caataaaatt catgttgtta
    25501 cagcaaataa agatttgtta gctgaatgtg gagatgagct tgcaaaatta gcaagtgaaa
    25561 ataaagtaag tattaaattt gaagcttcag ttgcaggagg tataccagta ttaaaaccaa
    25621 taatagaatc actagaagga aataatatag atagtataaa tgcaatttta aatggaacta
    25681 ctaattttat attatctaaa atgtatgatg agaatctatc ttatgatatg gcattaagac
    25741 aagcacaaga attaggtttt gctgaagcaa atccagagtc agatgtatta gggtatgatg
    25801 ctgctagaaa actatcaata ttatcaactc tagcttatga caatagagta tattggaaag
    25861 atgtgtattt agaaggaatt acagatatag atgaaaaaga tattgaatat gcaaaaaaat
    25921 taaattgtaa aataaaattg attggtcaaa gtaagtatga aaatgataaa gtaagtgctt
    25981 ttgttagacc tgttttagta gaaaaagata atatccttgc tagaatagac aatgagttca
    26041 atgctgtcat agtgaatgga gattcagtag gagaagtttc ttttgtaggt aaaggagctg
    26101 gaagtttagc aacaggaagt gcggtttatt cagatgttat agatataata gataatagag
    26161 tttcaagtat agattctttt actaaagata aaatacaagt taataaaata gttagagaaa
    26221 agtgtggagc acttcttaga tttaaaaaat gtaataaaga tgaaattcta aatatagttg
    26281 agaattgttt agtaaaattc gatattttaa atgatgatga tgaacttgct attatggttt
    26341 atgctgattc tgaatatgaa ataaacaaca gtttatgtct aataaaagat aaaggatact
    26401 gcgaaaaaat gaataaaatg ttgaaaataa gttaaaaaag aaaaaatata agtttatatg
    26461 taacatattt tgacgatttt aatactatat agtatgagat gaaacaaaac atctcataaa
    26521 aaaattaaaa ttaaagggag agatatgtta tatggaaaat aaaaaatgtt attcagaaga
    26581 ttggtatgaa agaggagaat ctacagctaa atggttccaa aatgatagag aagaatatga
    26641 aagagaagca tatgatgaag atagagaaag aagaggttca aactgtggat gttcagattc
    26701 aggagaaaat agacctagaa actgtgaaag atttagaaga gaagctgaga taagagaaag
    26761 agaagcaaga gaagcattct gtgaatcttc agagaaaaag aaagaggcat tagcatatga
    26821 atgtgaagct agaaaattat gggaagaagc agaaaaatac tgggatgaat attcaaaata
    26881 caactataaa ggaatcgaat atttagcaga agctgctaga ttatttgatg aaggtatgga
    26941 atgtgaagct agaagaaatg gaaataatgg aggaaacaat aataattgtt gccataaatg
    27001 ccataaatgt aattgtaact gctgtagaaa ataaaaaaat taattgacaa atcaatagtt
    27061 aaaatatatc atattatgta taataaagag aaaattcaga aaaaaataat gattagaaga
    27121 aatataagta tatttattag acaaatagtg ctcagttagt gaggtgagta caatatgatt
    27181 aaactcccat cctctagctt ttgatagagg gtgggagttt ttatttattt atatatctta
    27241 aatgaggata atattgtaaa ataaatgagt atgagattgt aaaattagga ggtaaaaatg
    27301 aaaagtatta aaacatcaag tatgaaagaa aaggtagatg aaaagatatt aagagagcaa
    27361 gtaagttcta taatagaaga tataagaaat aataaggatg ttgcacttaa aaaatataat
    27421 gagaagtttg atagaaatac aagagatgaa tttagaatta ctaaggaaga aataaaggaa
    27481 gcttataagc atgtagatga cgaatttata aataacttaa agattgctgc caaaaatata
    27541 agagaatttg ctaaagctca aaaactaagt tttgaaaacc cttttgaaaa agaaatttat
    27601 ccaggtgtaa tcttaggtca aactaatatt ccaatagagt catgtcttgc atatgttcca
    27661 ggaggtcagt atccattgtt ttcaacagct cttatgctta taatacctgc aaaagtagca
    27721 ggagtaaaaa gaatagtggc atgttcacca actatgaaaa atactgaaaa gataaatcct
    27781 aagacattgg tagctatgga tatagcaggt gctgatgaaa tatatgcaac tggaggagtt
    27841 caagctatag cagcatttac atatggaaca gaaaagatta atccagttga cataattgta
    27901 ggaccaggaa ataagtttgt aactgaagct aaaagacaat gttatggaca agtagggatt
    27961 gattttgtcg ctgggccaag tgaagttctt ataatagcgg atgaaacttc aaatccagtt
    28021 tatattgcag ctgatttatt agcacaatgt gagcatgatt taaatgcaag aggaatatta
    28081 ttgacaaata gcttggaagt agcacaaaaa gttgaaaaaa atatagaaag tatgctaaaa
    28141 gatttgccaa caaaggacat agcatatagt tcatgggaaa ataatggaga gataatattg
    28201 gttgatgata tggaagaagc cattaaaata agtaattttt atgcaccaga acatttagaa
    28261 gttgcagtaa atgagtataa tgatatttgt gatagattaa ctaactatgg ttctttattt
    28321 attggaaatc tttctgctga ggtgtttggt gactatgttt caggtaccaa tcatacatta
    28381 ccaacactta aagcatcaag atatactggt ggtgtttggg ttggaacttt tatcaaaact
    28441 tgtacaaagc agatatttaa tgaaaaagct atacaatcat tagcacctgt agctgaaaag
    28501 ctggcaaaag aagagggatt atatgcacat gcaaaggctg ctgaggttag gtttaaaaag
    28561 tagtaaaaaa ttttattttg gcagtcgaga cttagtatta gactgagata aggaaaacgc
    28621 tgagaacctg aataaatact atattttgtg ggtctcggcg cttcttttat atctgtatat
    28681 aatagaataa tactatctgt gtgtttaaat actaacttaa tatttctttt ctaaataatg
    28741 tttatgaaat agttaatatt tttagttaat acttgaaaaa aacttttgct aactgtgcaa
    28801 attcatctgc atttgtcaat atagcagggt gtcctccctg actaaaaatg taaatacttg
    28861 cttttgaaat aaaagttgcc atttgcttgt actcttcttc aagattatga cgacacattt
    28921 cgtcttcctt acttcctgta aataaaattg gcatttctaa tttacacaat tctttatgaa
    28981 acaaagggcg tttctcgttt gcacattgca atagagcttt tgtatcaaga ttaacaacat
    29041 tctcccaatc ttttccatga caccattcat agaattttcg tgcttgaata tcttgctttg
    29101 atttttccct tccagtgatt agattatcta tgaagttatc attaagagta cgtccatcaa
    29161 agctatctgc tataattgct tcaactaaat cgggacgttc taatccagta ttaacagctg
    29221 cccatgctcc tccacttgtt ccaattaagc caactttacc acaattcaaa tgttcaatca
    29281 gtgctattgt ctgtaaggct tcatcatgcc atatgtcagg agaaaattga gaaactctat
    29341 ccgactgtcc attacctaaa aaatcaatta agatacatct aaaattttct gcatataatg
    29401 gcacaagtgc tttaaacata ttagaagaac cagtattacc atgcaggaaa attatcggtt
    29461 taccttgtcc atattcttta taaaaacaag aattaccttg atactgaaaa tatgacatat
    29521 attttcctcc tttttatttg ttaagttaat tataacaata taggtatgaa tgaaaaacct
    29581 catgttcttt cttagaataa aaatgtgcca cgcataaaac gtgacacatt tctaattata
    29641 aattttgctg tttaagtatt ctttgtatgc ttttctctgt caaaaagtat ttctctgata
    29701 actgcttgat actcattcca ttttggaaat ttatacagat ttgagaatta cgagaagcta
    29761 agacttgttt ggtgtttgtg ttttcacccc aatgcttttt gtgctcttgc tttttgggaa
    29821 tataaatcac tttaccatct atatattctt gcacttgctc aatcagttct ttaggcagta
    29881 agtcaatcga attttgatag ctcattttgc acctcctaaa taattattct ttaggattag
    29941 caaaggctac tgccactcac aattaaaaat aaaatttttt attatgtaca atagcctttg
    30001 ctatgcacaa gttccaattc ccataaacta aatactcctt tctggtttga aaaattcatc
    30061 tgaacattga tttcgctttt aagatagagt tcaatgacaa atttacattt ttattatata
    30121 tattcagata gataattgca actgtctttg tatgaggata ttttattata gtcaatacta
    30181 taatatgtat ttatatcatc aaactaatat gaacagttga aaggaatatg aacaataaaa
    30241 cttagtcagg aagaataatt atgaagcaga caattgagaa atttgatttt aaagttttat
    30301 tgaaaattta ttgacaaatt taacttgtaa atattatact aaacttaata aataaagttt
    30361 ataaagtaag gtgttgtcta tgaaaaatat agttggaaaa ccgcaaacga taaaaaaagt
    30421 aaatgaagat ttaataaaaa acattataaa aaatgaaggt cctataacaa aaccagaaat
    30481 ttcaagcatt actgaattga gtttagctac agttaataag attgtagagc aattagcttt
    30541 gaaaaatgaa gttaaagtaa gtggactaag tgaatctact ggaggaagaa gagctcaatt
    30601 atttgaaata aatgcaaact tagaacacat aatagcttta tattattata gaaattgttg
    30661 tataggggta gttgccaatt tattaggtga aataatttat caagaagaat ttaatataag
    30721 aatggatacg tatgaaaacg ttaaccaaga tacttttttt gttatagata ctctaataaa
    30781 aaaggaaaaa ggaaacaata taagggctat tggaattggt gtcccaggag ttgtaaaaaa
    30841 aggtgtagtt aaaaatatac caactataaa aagttgggaa ggtataaatt tagaaaattt
    30901 aataaagagt aaatacaata ctaaagtgtt tatagaaaat gatacaaata ttactactat
    30961 tgggatttat caaaaacagt ataaagacaa atataaaaat atggctctta tgtatttaga
    31021 agatggtatt ggttcaggta tagttataaa tggtgaattg tatttaggtt ctacaaattt
    31081 tgctggagaa ttaagttatc taaatataga atttggtaag tataactcta acaacttaaa
    31141 tcttgaagat tatattatga gtttaagaaa aagatattta gaaagtaaag ataataaatt
    31201 taagaaagaa attttatcta taatatcaaa ctttataagg actcttgtat gtgtcctaaa
    31261 tccacaagct atgattatac agtgtagtat attaaccaag agtgacatgg agtttataga
    31321 aaaagatgta agcaataatg ttggagaaga aaattttcct aaattaataa aagtagactc
    31381 attgagagaa ggaagtataa atggagtaat tagtatgtgt ttaaaagaaa ctgactatca
    31441 atattcctta tctaataaaa aaggaggata ttaatgtgaa atatttggtt tcaatagatg
    31501 gagggggaac aaaaactaaa ttttgtgtaa gtgacttaga tggaaacata cttaaagaac
    31561 ataccactgg ttcaactaat tataagtcag ttggaattaa aaaaacatat gaaaatatta
    31621 ataatggatt taaaaaaata ttaaaagatt tatatatcga ttatgacgat attgagtaca
    31681 ctgtatttgg tatatctggt tgtgattctc ctaatgatta taagattata atggatgaaa
    31741 tattaaaaat tgggattaac aaagaaaaaa tatatctggc aaatgatgca gttttagctt
    31801 tttatgcaca agctgattcc cctggtttag taattgtggc tgggacaggt tcaattatac
    31861 tgggaattaa agaagatgga gaaatatata gagttggtgg atgggggtat aattttagtg
    31921 atttgggttc tggatatgat atagggagaa aattattaaa gaaagtattg ctttattgtg
    31981 atgaatgtca tgagtatagt gatttattta gttgtgtctt ggacttcttt ggagcaaata
    32041 gttttgaaca acttgcatat atgattactg atataaatga taatgttgaa atagcaaact
    32101 tagcttcatt agtgattgat tgtgccgaac gaggtgataa attggctatt gaaatattaa
    32161 gagaatcatc aactgaacta tctaaattag ctcaagtaat attgagaaaa atatctaatc
    32221 caatgaaaat ggataaaagc gaaataaata tagttttgtc tggtggtaca ttaaataaaa
    32281 ctgtatatgc tcaaatgtta atgaataatt taaaaacaga aaatacagat aaaaatttaa
    32341 aatttatatc tcaagaaaat cagccagtat atggggggat aagacttgct atggcattag
    32401 ctaataggag ggtcaatcat ggatagaaaa aaggtaatag tacaaatttt tactggaggt
    32461 tttaaggcta aagaaataaa gtttaatgat ataaaatgta aactactaga attattggac
    32521 tgtattgata tagaaaaggt tatcatggga tggagtgtag atgaagaatt atatgtagaa
    32581 actaaaaaac tattaaataa atataatgtt gaactatatc tttggttgcc atgtttttct
    32641 gaaataggat tacttgaaaa aagtaattta ctaattgatt atatggggaa ggaagtcaag
    32701 ggctatgctt tacaagagga tgaaaatttt gagttttatt gcccaaataa taaggaaaat
    32761 ataaaaaata taaagaaaat atatagtact tattttagtg atattaaatt tgatggaatt
    32821 tttttagata aaataaggta tggttctttt tcgaataaac taaatggtgt ttttaattgt
    32881 ttttgtaaag attgtttaaa tatatatgaa aaaaataata ttgataaaga gtcgttaatg
    32941 agagaaatga ataatgtgtc taagggagtt atagataatg aagatactcc atttggtata
    33001 acagaataca ttaatggaaa atacaaattt aaaaataaaa tatgggaaga tttttttgaa
    33061 acaaaaaatc aaaatatata caaggcatta ttagagataa gtagttattt taaaagtaag
    33121 ggattgaaaa taggtataga tactttttct ccttttattt cttactttac aggtcaagat
    33181 ttagaaaaat tacaagaagt agcagatttt ataaaaccaa tgatgtatag aactacaaaa
    33241 gctccagctg gtttaccatt tgaatttgaa aggtttattg atgaatccat acataagaat
    33301 aaagagattg gaaaaagaaa tttcttagat attttaggaa ttaaggagta tgaaggagat
    33361 gtatacccta tagaatttgt actagaggaa atcgatttta tgacaagaaa tcttaataaa
    33421 gatgtatatg taggagttga aataaataaa aaggaaatta tatctcctgt tacacctaag
    33481 tacataagtg aaaatatttc aaatataaat aagacaacag taaaaggata tgttttatct
    33541 tgggatttgt tgtcagcacc aaaagaaaat attgatgaaa ttataaaatg gtttcggaat
    33601 tagtgaggtg ataaagtgag taagatattg gaaatgcaac aaatatataa aagttttgga
    33661 aaggtagatg ttttaaaagg gataaatttt gagttagaaa agggagaagt aagagctctt
    33721 ttgggagcta atggagcagg aaaatctaca cttattaaaa ttttaggagg agttcattct
    33781 caaactaaag gtaaagtaat tttgactggt aatgaaataa tgtttaaaaa tccacatcat
    33841 tctaaagaaa atggtattag tataatttat caagaattaa gcttgatacc aacgcttaca
    33901 gtacttgaaa atatttttct tggtagagaa attttaaaag gaagtgtgtt tttaaacaag
    33961 aaagacatgc ttgaggaata tatgaaaatt tgtgaggatt ttgattttaa tatagaccca
    34021 catatagtag tttctaattt aagtgtagca aaccaacaaa tggttgagat aatgaaagct
    34081 gtttcatgta attctgaaat tatcataatg gatgaaccta caacatcact tactaataat
    34141 gaaaaagatg ggctatttaa aataataagt agactaaagt ctaaaggtaa aacaatagtc
    34201 tatatttctc acatattaga ggaagttttt aaagtatgtg atagtgcaag tataatgaaa
    34261 aatggaatta tgattggaac ttatgatgta gaggatttaa ctaaattaaa gataactcaa
    34321 cttatgacag gaaatgataa tcacaaactt attgagaaga aggattatac atttgcaaaa
    34381 tatgaagagc caccagtact agaagtaaag aatataagct ggtctaacaa aataaaaaat
    34441 gtttcattta aagtttatag aggcgaagtt gtaggtcttg caggtcttgt aggttcaaga
    34501 agaactgaaa ttataaattt gatatttggt atagataata aagatagtgg agatattttt
    34561 atcaatggta aaaaagtaga cataacttct cctaaggttg ctataaaaaa caaaatagga
    34621 ttgattcctg aagatagaaa aaatctagga ttaattttag aacaagctat atacacaaac
    34681 tcatcatcag tacaaattga taaattcaag aaattcttgt ttatagatag aaataaagaa
    34741 attgagtttt ctaaaaaagg tgttaaggaa ttaggaataa aagttagtga tgtaaagcaa
    34801 gaagtaaaag agcttagtgg tggaaatcaa caaaaagtag tagtttctaa gtggttagag
    34861 aaagatttag atttaataat atatgatgag ccgacaaagg gaatagatat tgctgcaaaa
    34921 gaagatattt tcaatacaat caaagaattt tcaagtaaag gaataggagt aatatttata
    34981 tcttctgatt tagaagaagt aataagagta agtgatagaa ttttagtaac tagagaaggt
    35041 tctattgtag atgatttaaa aaatgagaat atacaggttc aagatataat gaacagtata
    35101 tttaatgtat aaaaaatgaa aatggaggac tgaaatgaag aaagcttttg agaagttaaa
    35161 tttaagagat tatggagtat tattaggttt tttagcttta tgtatagcta taagtattgc
    35221 aactccatca tttttaggta aacaaaatat acttaatctt ttacgacaat cttctataat
    35281 tggaataatt tcagcaggta tgacttttgt tataatatct ggaaactttg atatatcagt
    35341 tggagcagta gcagctcttg caggtgctat aacaatgaaa tttgcgactg gtggaactaa
    35401 tttgtttgca tccatgctct taggtgtagc gatttgtgca gtaataggat taatcaatgg
    35461 tatagtagtt gcaaagataa atgtaccatc attaatagcc actatggcta tggtcactat
    35521 tgtaagagga ttgctgttga tgcttacagg aggatatcca attactgaaa atataccaat
    35581 acttgattac attggaaatg gatatttgtt tagtatacca ataccagtag taattttctt
    35641 tatagtggtg ttagcttcgt ttattgtact taataaaact aagtttggta gatatgttta
    35701 ttctgtagga gggaatcaag aagcaagtaa acttaatggt ataaatgtag attctcacaa
    35761 agtgaaagtg tttattatta atgctgtact tgcaggaata gctggaatcg tactaacagg
    35821 aagacttggg actgcaactg cgattgcagg tgaaggatat gatatggatg caattgcatc
    35881 tgtagtaata ggaggtacat cagtggcagg aggttctggt tctgtactta aaactgttat
    35941 aggagtatta cttatgagtg ttataaacaa cagttttaat cttcttggaa tagatgtata
    36001 tttccagtac atatttaaag gattaataat tttagcagca gttggatttg attcttatag
    36061 caagaaaaaa cttgcttcaa gataaaaaat aagggggatt tttttatgaa aaaattaatg
    36121 aaacatttag cattgttgtt atcacttgtt atgatatttg gtttagttgg ttgttcaaat
    36181 ggtggtgaca aagaaaaaaa tggagaaaag aaaatagcag tattactacc aggttcaaca
    36241 ggttactttg tagcaactaa acaaggtata gatgcaaaat ctaaagaatt aggtgtaagc
    36301 gttgaatatg cagatgctca atgggatgct agtaaacaat tatcacaagc tgaagatttt
    36361 atggctaaag gggtagacat gattgcatta tgtggagttg attctgctgt aagtgagaga
    36421 atagttaaag ctgctaatga ttcagacgtt cctatagtag catttacaaa ttctatagga
    36481 agtaacccaa ctggagaatt taaaggttta gttacatata tagggcaaaa tgaggaagaa
    36541 acaggagcat taactggaaa aattgctaaa aacttattag gagaaactgg tgggaaagct
    36601 gtattaatag aaggagtacc aggaactact ccacaagtat taagaaaaaa aggtcttgaa
    36661 aaagaattaa aagatagtaa tatagaaata gtttataatc aaacttcaaa ttgggagaaa
    36721 gagcaagctt taaaggtaac agaagattta attcaaaaga aaactgattt taatgttata
    36781 atatgtcaag atgataattc tgctacaggt gcaggtcaag ctttaaaaga tgctggtctt
    36841 aaggataaag ttaaagtcat aggtttgggt ggaagtaaag atggattaaa agctataact
    36901 gatgggttaa tagatggtac aacttatatg tctgctgtag aagaaggtgg attagtcata
    36961 gaaaaggcat ctaaattcct taaaggtgaa aaaatagaac ctgttacaca aattaaacaa
    37021 gttgaagtta acaaagataa tatttcagag ttcaagggtg aatggtaaat tgtcatagat
    37081 aataaataag atttttagag ttactttaga aactatataa agtaactctt tttttaattt
    37141 aatttagtga taaattattg aatagtattt ctaaacaaat aaaaaattaa tataaacaaa
    37201 gacttaatta tactaaatta taagtaaaac taatataaac ttatggaaaa aaggaaaacg
    37261 tctaaagcat tggaattact atagtgtagg tgtggtatta aaaaaacata aaaaaacata
    37321 aaaaaattgt tgaaaaaaat atagaaattt tgtataatta aagatttgaa aagtgcggta
    37381 tacaaagcca attcttttgt atataatata tataaattca gaaaaaggaa gggatatgta
    37441 tggccaggcg gttattttta gaaaggattg gacttatatt tttaggttca gcaatattag
    37501 catttggagt ttataatttt tattatttaa acaacataac agaaggtgga gtgttaggta
    37561 ttttactact gttaaaaaat ttattcaata tacaaccagc aatagcaaat gttgtaatag
    37621 atggtttact acttttagta ggatataaat ttttcggtaa aaaattcctt atatattcaa
    37681 tagtagcttc tataactttt tcagtgttat atgacttatt tgaagctata ggacctctag
    37741 taccacaatc acaaaatatg cttttatcaa ctattttggc aggtgtaact gttggaactg
    37801 gtgtaggtat agtagtaaaa gcaggttgtg catcaggagg agacgatgct ttagcattag
    37861 taatttctaa gactacatct ttgaacatag ggcaagttta tttagcaaca gatgttattg
    37921 tattgttgtt atcattattt tatctatcag cgtttgatat cttttattct ttgattgctg
    37981 ttacaattag tggcaaggta attgatttta tttattatca tggtaaaagt ttggatatgg
    38041 atataagtaa tgatatagtt ccagaatgtt aatataaatt aaataacttt agattttatt
    38101 aggggtggca gatttgccac cttttttgtg tctaaatctt tatagaaagt ataatcccat
    38161 ctaggttttt gcaaatctca aatatagaat tatgttggaa tgactgggaa tacgattgcc
    38221 agatgtgcat tttaaaaacc aaattttata tttatgaaat actaatcatt aatggatgtt
    38281 tcttaatcct atctttatac ctaaaatgat aagataaatg aagtagcaat acaaagctaa
    38341 aatttgtaaa agagattaaa ttaaatggag gagctaaaat gttggatata gttatgatag
    38401 cattgttatt cataggattt gtttccatga agttacttgc tgattggtgt gggaaacaaa
    38461 ctgaaaaaaa ataatgtaat gtatggaggg attacctatg tggtttctgg cagttgtaat
    38521 tataatgtta ataatatatt tggtatatgc gcttattaat cctgaaaaat tttaaacagt
    38581 ataaggctaa taagtaagtt gaattggggg gaacaatttt tatggtgcag atagtaatag
    38641 tgttagcgat ttttatgatt ttagtaatac ctatgggcaa gtatttatat catatagcta
    38701 ctaatcaaaa aacatttgga gatagactat ttgataaagt ggacaatttt atatataagg
    38761 tatgtagtat agataagaaa aaagaaatga actggaaaca gtatgcatta gctttattat
    38821 ttacaaatgc agttatggta tttataggat atatcatact tagaactcaa agtatgcata
    38881 tttttaatcc aagtggaatt aaaagtatgg aacaaggact atcatttaat acaataataa
    38941 gttttatgac aaatacaaat cttcaacatt attcaggtga atcaggactt tcatacttta
    39001 gtcagatgac ggtgataata tatatgatgt ttacatcagc tgcaacagga tatgcggctg
    39061 ctatggcatt tgtaagaggt ctagtcggta aaaagaaaac attgggaaat ttttatgtag
    39121 atttaattag gataacaaca agagtacttt taccaggagc tttaattatt gggcttatat
    39181 tagttacaca aggagtacca caaacttttg ctgggacaga aacagtgact actatagaag
    39241 gaaagcttca agatatagct agaggtcctg tggcagctct tgaatcaata aaacatttag
    39301 gaacaaatgg tggtggattc tttggttcaa attcatcaca cccatttgaa aatccaacaa
    39361 taatatcaaa tatagtagaa atattatcta tgatgatatt accaggagct tgtgttgttg
    39421 catttggtca catgataaag aataaaaaac aaggttgggt tgtgtttggc gcaatgtcaa
    39481 tcatattttt aataggtcta gtagtgtgct ttaaagcaga aagtgcagga aaccctattt
    39541 tatcacaatt agggcttaat caaagtatgg gaagtatgga aggtaaggaa gttagatttg
    39601 gtatagcaca atcatcatta ttcacaacag tgactacttc ctttacgaca ggtacagtta
    39661 ataatatgca tgatacactg actcctttag gaggattagt accactttta aatatgatgc
    39721 taaatgtagt atttggtggt aaaggcgtag gtctgatgaa tatgttgatg tacgctataa
    39781 tagcagtatt cttatgtgga ttaatggtag gaagaacacc agagttttta actaagaaaa
    39841 tcgaaggaaa agaaatgaag cttattgctt tacttattat attacatcca cttttaatac
    39901 taatgttctc tggtctttca gtagcaatac cagcggggct tgaaggaatt tcaaatcctg
    39961 gattccatgg attatcacag gtattgtatg agtttgcatc ttcagcagct aataatggtt
    40021 caggatttga aggtctagga gataacacta tgttttggaa tataacaaca ggtatagtta
    40081 tgttctttgg aagatatgtg tctattatag tactactagc aatatcaagt ttgttagcat
    40141 ctaaaaaagc tgtaaatgaa agtataggaa cacttagaac ggataatttt acatttacaa
    40201 tagttttagt acttgttgtt ttaattgttg gtgctttaac atttttccca gccttagcgc
    40261 ttggacctat ttcggagcat ctagtgttgt ggcactaaaa aattgggagg gagtaaagtt
    40321 ttatggaaac taaaaaaaca aagtttatta caaaagatat tttcaaaact tccattatag
    40381 aagcttttaa aaaattaaat cctaaatata tgatgaaaaa tccagttatg tttgttgtag
    40441 aaattggatt tatagtaaca ttgatactta caatagtacc tagtttgttt ggtgatgaag
    40501 gcaataactt aagagcttat aatgggattg taacaataat cttatttata acagtccttt
    40561 ttgcaaattt tgctgaagct gtagctgaag gaagaggtaa agctcaagca gatacactta
    40621 agaaaactag aaaagataca gtagcaaggg ttatagatac gttaggaaat gaaaaaatga
    40681 taagtgcaag tgagctaaaa cttggtgata ttgttttagt aaatgctgga gaagttatcc
    40741 caaatgatgg agaagttata gagggtatag cttctgtgga tgagtcagca ataactggag
    40801 aatctgcacc tgtcatgaga gaatcaggtg gagatttcgc atctgttaca ggtggtacta
    40861 cagttgtaag tgactggtta aagataagaa taacaacaaa accaggagaa tcgttcttag
    40921 ataaaatgat agctcttgta gaaggtgctt caagacaaaa aacgccaaat gagattgctt
    40981 taaatacttt gttagtaggg ttaacactta tatttatggt tgttttaata tctctttatc
    41041 caatggcaaa ctatgcaggt gtaaagattc caatttctac tatgatagct cttttggtat
    41101 gtttaatacc aactactata ggtggattgt tgtcagctat tggtattgca ggtatggata
    41161 gagtaactag atttaatgta attgcaatgt caggaaaagc agtagaagct tgtggagacg
    41221 ttgatactat gattttggat aagacaggta cgattactta tgggaataga cttgcatcag
    41281 aatttatagc agttggaaat gcagattcaa aagatttaat aaattattct gttatgtgtt
    41341 cattaaaaga tgatacacca gaaggaaaat ctatagttga tttaggtatg aaattaggtt
    41401 caacaggtaa gacaaaagag gcagaggaag ctgagtttgt agaattttct gcacaaacta
    41461 gaatgagtgg tattaactta gctgatggta gagctataag aaaaggtgct tatgatagca
    41521 taataaaaag agtaaaagaa tctggtggta cagtgccaga agatttagaa gaaaatgtaa
    41581 atcgagtagc taaactagga ggaacacctt tagtagtgtg tgtagataat gagatatatg
    41641 gaattatcta cttaaaagat acagtaaaat cagggcttgt agaaagattt gctagacttc
    41701 gagagatagg aataaagaca ataatgtgta caggggataa tcccttgaca gcagctacaa
    41761 ttgcaagaga agctggggta gatggattta ttgcagaatg taaaccagaa gataaaatag
    41821 atgcaataaa aaaagaacaa ttagagggta aaatagttgc aatgacaggt gatggaacaa
    41881 atgatgctcc tgcacttgct caggcagatg taggtcttgc aatgaatagt ggtacaacat
    41941 ctgcaaaaga agcagcaaat atggtggatt tagattcaga cccaactaag atattggaag
    42001 ttgttgaaat aggaaaacag cttttaataa ctcgtggggc tttgacaaca tttagtatag
    42061 caaatgatgt tgcaaaatat tttgcgatta taccggctat atttactctt gcaatacctc
    42121 aaatggagat attaaatgta atgaaacttt ctacgtcatt tagtgcgata ttatcagctt
    42181 taatatttaa tgctataatt atcccatgtt taatacctct tgcaatgaag ggagtaaaat
    42241 atagacctat gaaatcacaa gctatgttaa tgagaaatat gcttatattt ggtcttggtg
    42301 gagttatagt accattttta ggaataaaat taattgattt attgattaca cctttagtaa
    42361 tggttcttaa tttaggttaa taaatggagg atataaaaat gaaaacatta aagccagcat
    42421 tacttgtaag tattgtattg ttagttgttt gtggacttgt atatccactt gttttgacag
    42481 gtgtaagcca agttgcattt aaagataaag ctaatggaag tatgatagaa gtaaatggtg
    42541 taaaagtagg ttcagaactt attggtcaaa gctttacaga tgcgagattc tttaagggaa
    42601 gagtatcatc agtaaactat aatacttata caaaagaaga tttagtacca gataaagatg
    42661 gaaatacatc ttatggaggt gtatcatcag ggtcttttaa ttatggagct acaaatccag
    42721 aacttcatga tagagtgcaa aaagatatag aaaagttttt aaaggataat ccaactgtca
    42781 aaagagagga tataccaaca gatttactta cagcatcagg ttcaggactt gaccctaata
    42841 taagtccagc ctctgcaaaa attcagatac cagctatagc aaaagcgtct ggaatatcag
    42901 aaagtaaatt acaaaaaatt gtagatgata atacttccaa aaaacttttt ggagttttag
    42961 gtgaagatag agttaatgta ctaaaggtta atgtagaggt cgcaaaaata ttaggtctta
    43021 tatagtattt tgtagaattt tagtaacaaa atattacgca agatttaatt taaaggttaa
    43081 attttaaaga gtgaaaatca ataatgattt tcactttttt atttgaatat tactaatatt
    43141 tggaataaag tgattgtaag tataaaatcc aaaaaaaggt tgcattatca aaatgataat
    43201 actataatat atttatcgtt atcaatttga taatagattt ggacatatag gaggaaatag
    43261 tatgttatat aataacgcat tagagttgat aggaaacaca cctgtagtaa ggctgaataa
    43321 tttaggctgt actaatgggt gttctaacat atatgtaaaa ttagaaaaag taaatccagc
    43381 aggaagtata aaagatagag ctgtttatga aatgttagag ggcttagagc aaagaggaga
    43441 attaaaaaag ggagatgtac tagttgaagc aactagtgga aatactggta ttgcattatc
    43501 tatgatagga aaattaaaag gatatgaagt agtaatcgta atgcccgaaa caatgagcgt
    43561 tgagagaaga gatttaatga aggcttatgg agcaaatttg gtgcttacag atggtaaagc
    43621 tggaatggca ggttccatag aaaaagcaaa tgaactttta aaagaaaatc caaactataa
    43681 aagcctaaaa caatttgaaa ataaagataa tccaaatgca cattataaaa caacagcagt
    43741 tgaaattatg aatgatgtca aagatttaga tatattcgta tgtggagttg gaacaggtgg
    43801 tactttaata ggaactgcaa gatatttaaa agaacaaaat ccaaatataa gagtaattgc
    43861 acttgaacca aaaaaatctc cagctatatc agaaaacaag actggacctc ataaaataca
    43921 aggaataggt gctaactttg ttcctgaaaa ttatgattct agtgtagttg atgaagtaat
    43981 attagtagat gatgaagatg catttgatac agttaaatta cttgcagcaa aagagggaat
    44041 tttagtaggg atatcttctg gagcaaatat atttggtgct atagagatgg caaaaaagta
    44101 tccagataaa aagatagtta cagtagctcc agatggagtt gataagtata tgtctatggg
    44161 aatattttaa taattttatt tgagggagtg aatactttgt ttaagaaaat aaataaagat
    44221 attgaatata taatgaagaa tgatccagca gctaggtcta agatagaagt ttttttactt
    44281 tatccatcag ttcatgcaat gataatgcat aggatggctc atgctcttta taagaagaag
    44341 aagcttttta cagcaagatt aatatcccag atatccagat ttatgactgg catagaaata
    44401 catcctggtg ctaaaatggg ggaaggtata ttgatagacc atggaatggg tgttgtaatt
    44461 ggagagacag cggaagtagg taatagggtg acaatatatc aaggagctac tttaggagct
    44521 acaggaaaag atactggaaa gagacatcca actgttggtg atgatgtatt aattggtgct
    44581 ggaacaaaaa tactaggacc tttaaatata ggttcaaatt caaaaattgg tgcaaattct
    44641 gttgtcgtta aggatgtacc taatggtgca acagttgttg gtataccagc aaaaatagta
    44701 aaaataagaa acctagaacc tgtaaaaaag aataaaaaag aagtgtccta tgagtatgat
    44761 gaattagata atgtatatta tatataggat ttatataact a
//
LOCUS       DAEPUT010000027        44677 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.027, whole genome shotgun sequence.
ACCESSION   DAEPUT010000027 DAEPUT010000000
VERSION     DAEPUT010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44677
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.027"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(11..1000)
                     /locus_tag="KRL22_001617"
     CDS             complement(11..1000)
                     /locus_tag="KRL22_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBH1272114.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            1440..2195
                     /locus_tag="KRL22_001618"
     CDS             1440..2195
                     /locus_tag="KRL22_001618"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH1272115.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            complement(2626..4257)
                     /gene="bclA2"
                     /locus_tag="KRL22_001619"
     CDS             complement(2626..4257)
                     /gene="bclA2"
                     /locus_tag="KRL22_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HBH1272116.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGPTGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGATGATGVAGA
                     IGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGATGANGVAGPIGPTGPT
                     GANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTGPTGANGATGATGATG
                     ATGANGATGPTGATGATGVLATNNAQFTVSSSSLVNNTLVTFNSSFINGTNITFPTSS
                     TINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAKAVNTLTSSDVSVSLS
                     FLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(4615..5154)
                     /gene="hpt"
                     /locus_tag="KRL22_001620"
     CDS             complement(4615..5154)
                     /gene="hpt"
                     /locus_tag="KRL22_001620"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH1272117.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGRVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(5482..6789)
                     /locus_tag="KRL22_001621"
     CDS             complement(5482..6789)
                     /locus_tag="KRL22_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBH1272118.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(7214..8989)
                     /locus_tag="KRL22_001622"
     CDS             complement(7214..8989)
                     /locus_tag="KRL22_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1272119.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLERMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(9201..9770)
                     /locus_tag="KRL22_001623"
     CDS             complement(9201..9770)
                     /locus_tag="KRL22_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1272120.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(9954..10589)
                     /locus_tag="KRL22_001624"
     CDS             complement(9954..10589)
                     /locus_tag="KRL22_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH1272121.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            complement(11257..12138)
                     /locus_tag="KRL22_001625"
     CDS             complement(11257..12138)
                     /locus_tag="KRL22_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH1272122.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            complement(12258..13265)
                     /locus_tag="KRL22_001626"
     CDS             complement(12258..13265)
                     /locus_tag="KRL22_001626"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HBH1272123.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            complement(13285..13767)
                     /locus_tag="KRL22_001627"
     CDS             complement(13285..13767)
                     /locus_tag="KRL22_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBH1272124.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            complement(13785..14252)
                     /locus_tag="KRL22_001628"
     CDS             complement(13785..14252)
                     /locus_tag="KRL22_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBH1272125.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            complement(14267..15025)
                     /gene="prdD"
                     /locus_tag="KRL22_001629"
     CDS             complement(14267..15025)
                     /gene="prdD"
                     /locus_tag="KRL22_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HBH1272126.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            complement(15105..15830)
                     /gene="prdB"
                     /locus_tag="KRL22_001630"
     CDS             complement(15105..15830)
                     /gene="prdB"
                     /locus_tag="KRL22_001630"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(15378..15380),aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HBH1272127.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            complement(15868..16152)
                     /locus_tag="KRL22_001631"
     CDS             complement(15868..16152)
                     /locus_tag="KRL22_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272128.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            complement(16233..18113)
                     /gene="prdA"
                     /locus_tag="KRL22_001632"
     CDS             complement(16233..18113)
                     /gene="prdA"
                     /locus_tag="KRL22_001632"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HBH1272129.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            complement(18542..20302)
                     /gene="prdR"
                     /locus_tag="KRL22_001633"
     CDS             complement(18542..20302)
                     /gene="prdR"
                     /locus_tag="KRL22_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HBH1272130.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            complement(20709..22892)
                     /locus_tag="KRL22_001634"
     CDS             complement(20709..22892)
                     /locus_tag="KRL22_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBH1272131.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTPDVEKPSDGQVPDGEKPSDSQVPDGEKPSDGQVPDGEKPSDGQIPDGEKPS
                     DGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKPSDSQTPDVEKPSDGQMPDGEKPLDEQ
                     TPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEEDVKADEQSEINQ
                     VFTSKDSFISLWYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTLTFDYVIKGLVG
                     ASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQENQNEEAVKSIL
                     YAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWIILGQMDEQERLKQYQGSINLCD
                     KLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAGREELKPNDTGKPSLSNGLTKIN
                     FEKNEDGTYETEAVALVGYSGVVKLRLPDGVTAYDGDGNIIGTDEVEISTQQKFKLKS
                     VGKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQNLLSYTIEKKNG
                     QEVNFNIGLPTDDDDVVNPPVPPIDDDVVNPPVPPTDDTNGHKPKPSPPIDDTVINPP
                     VPPMDDTIINPPVPPTEDAVLNPPVPPMEDAVLNPPVPPTDDTVLNPPVPPVSDTVEK
                     TPELSRDDTIVKSPKTGDETQLMSYVFISVIAICGLAYQCKIKRN"
     regulatory      complement(23474..23559)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(23963..25276)
                     /gene="prdC"
                     /locus_tag="KRL22_001635"
     CDS             complement(23963..25276)
                     /gene="prdC"
                     /locus_tag="KRL22_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HBH1272132.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     gene            complement(25665..26429)
                     /locus_tag="KRL22_001636"
     CDS             complement(25665..26429)
                     /locus_tag="KRL22_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1272133.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            26720..26923
                     /locus_tag="KRL22_001637"
     CDS             26720..26923
                     /locus_tag="KRL22_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH1272134.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            27114..27650
                     /locus_tag="KRL22_001638"
     CDS             27114..27650
                     /locus_tag="KRL22_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HBH1272135.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(27654..28520)
                     /locus_tag="KRL22_001639"
     CDS             complement(27654..28520)
                     /locus_tag="KRL22_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBH1272136.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            28668..28913
                     /locus_tag="KRL22_001640"
     CDS             28668..28913
                     /locus_tag="KRL22_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH1272137.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            complement(29027..30325)
                     /locus_tag="KRL22_001641"
     CDS             complement(29027..30325)
                     /locus_tag="KRL22_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBH1272138.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(30458..31489)
                     /locus_tag="KRL22_001642"
     CDS             complement(30458..31489)
                     /locus_tag="KRL22_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH1272139.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCL
                     DIEENNEKLFKCSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            complement(32535..33245)
                     /gene="rgaR"
                     /locus_tag="KRL22_001643"
     CDS             complement(32535..33245)
                     /gene="rgaR"
                     /locus_tag="KRL22_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HBH1272140.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            complement(33670..36336)
                     /locus_tag="KRL22_001644"
     CDS             complement(33670..36336)
                     /locus_tag="KRL22_001644"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBH1272141.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPEKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     misc_binding    complement(36412..36674)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(36969..37796)
                     /locus_tag="KRL22_001645"
     CDS             complement(36969..37796)
                     /locus_tag="KRL22_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1272142.1"
                     /translation="MKIKDNKAVFHVFIRIFIIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     gene            complement(37844..39280)
                     /locus_tag="KRL22_001646"
     CDS             complement(37844..39280)
                     /locus_tag="KRL22_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HBH1272143.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     NLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            complement(39367..40236)
                     /locus_tag="KRL22_001647"
     CDS             complement(39367..40236)
                     /locus_tag="KRL22_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH1272144.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKIIRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            complement(40394..41047)
                     /gene="phoU"
                     /locus_tag="KRL22_001648"
     CDS             complement(40394..41047)
                     /gene="phoU"
                     /locus_tag="KRL22_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBH1272145.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            complement(41075..41839)
                     /gene="pstB"
                     /locus_tag="KRL22_001649"
     CDS             complement(41075..41839)
                     /gene="pstB"
                     /locus_tag="KRL22_001649"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBH1272146.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            complement(41858..42682)
                     /gene="pstA"
                     /locus_tag="KRL22_001650"
     CDS             complement(41858..42682)
                     /gene="pstA"
                     /locus_tag="KRL22_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBH1272147.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            complement(42684..43601)
                     /gene="pstC"
                     /locus_tag="KRL22_001651"
     CDS             complement(42684..43601)
                     /gene="pstC"
                     /locus_tag="KRL22_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBH1272148.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYAIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            complement(43982..44428)
                     /locus_tag="KRL22_001652"
     CDS             complement(43982..44428)
                     /locus_tag="KRL22_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272149.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVS"
BASE COUNT        13719 a         8211 c         5021 g        17726 t
ORIGIN      
        1 tttttataat ttaataaata gaactgctgt ttaccactgg ttgtgcatct ttattgccac
       61 aaagcacaac taacagatta cttaccatag ctgctttacg ttcttcgtcc aaagtcacaa
      121 cattattttc acttaaatta gtcaatgcca tctctaccat acttacagcc ccctcaacaa
      181 tctttttacg tgctgctatt atagcctctg cttgttgacg ttgtaacatt gctgctgcaa
      241 tctctggtgc ataagaaaga tgagtaattc tcacttcaca cacttcaatt cctgcaatgt
      301 caacccttga ttgtaattca tcttttaatc tatctgctat ttcctgacta ctaccacgaa
      361 gagatttttc atctccatct tcagatacat catatggata aagtcttgaa acattacgaa
      421 tagtagaatc acactgaata gataagaatg tattataatt atccacatta aatactgcct
      481 ttgttgcatc tataaccttc caaattacaa ccactcctat tataattgga tttcccaata
      541 aatcattgac tttctgcttt tcattattaa gagtcattgt ttttaaagat acttttttgc
      601 cccttgaatt agttgatata tctacctttt catcagatga agatttcgat acattaattc
      661 ttgatactgc tgggtttatt gctgaacaaa atggattcac ccaatagtac ccttcttttt
      721 ttatagttcc ataatagtta ccaaacaaaa ctagaactat agcttcttta ggattaatca
      781 tttttagccc aaaaaatagg ataaaatcta ctactataaa tacaagtccc aaaattaaca
      841 taagtgaacc tattccagta aatccactat caagttttac tatcccaaaa accatgatac
      901 ctattgaaac tactaaaaat aataaaatca ttatcaaagc tgccactcca ttgaatactt
      961 ttgcgtcttt ctcttgataa gttttttctt cttttaacat atctatcact cccatctcag
     1021 tatattaagt taagatattt ctaatttaat aataacactt ttaacaatta aattgttgaa
     1081 tttaaaatta atactatatg tttatatatt ttttatacat ctttatgcat acatgtattt
     1141 agttatttta atgtattaat attaatttcc aaataaatca tatgatatat gaatatggta
     1201 tttcaaaatt aactttttag ttcatggggc actctttttg gtatgaagtc aaatatattt
     1261 ttatcattta aacaatgaaa aagaaattta tctatatttt gaaaaatcca cttaaatttt
     1321 ttaatgtaag ataaattgta agcttattat cactaatatt attttatata aattatatta
     1381 gtgataaaat aaacttatag aaatataaca aatttttatt aatttcatag gaggaattta
     1441 tgttgaaagt tataattagt ggctataatg gaacaatggg aagagtttta gcagaatgtg
     1501 taaaaaaaga taatgaatta gagttggttt gtggtgtagc taggtctgct gatgaaaaag
     1561 gtcatcatag tgatacaaag ctttacaaaa caatgactga tgtaactgaa aaaactgatg
     1621 taataataga cttttcacat catgagactt tagagccaat attgtcatat gctctaaaaa
     1681 ataatacacc tgtagtatta gctactactg gatatgatga aaatgactta aataaaatag
     1741 aagaagcatc aaaaaacatt cctatattat tatcatcaaa tacatctctt ggagtgaata
     1801 tattaataaa attagttaag gatgcttcaa agatgttaga aggttttgat attgaaatca
     1861 tagaaaaaca tcacaataga aaagaagatg cccctagtgg aactgctact atgatagcta
     1921 atgcaattag agaagtcttg cctgaaagtg aaaatacaca tggtagatat ggtagagatt
     1981 gtaaaagaaa accaaatgaa attggaatac actctataag aggtggcaat ataatcagcg
     2041 accatgatgt tatatttgca ggtgataatg aagttcttac attaagccat cattctcaat
     2101 ctgatgaagt atttgcaaac ggttctatag ttgcagctaa atttttaatt ggtaagcaat
     2161 ctgggcttta taaaatgtca gatatattag gataagtttt gtacataata aatctcaatc
     2221 tatttaggta ttcatattca tcaatttgaa tatctaattg attgagattt ctattctaaa
     2281 agtttataaa ttttatgctt accttttaaa tataatcatt tttcttaaag gttatcttat
     2341 ttattggtat atggaattat attgtttatt attttataat ctcttcatca tataaaccta
     2401 ttaaatatta tcctatttat tggtatatgg aatcatattg tttattattt tataatcttt
     2461 tcatcatata aacctattaa atattatcct aatttattgg tatatgaaat catattgttt
     2521 attattttat agtcttttca tcatataaac ctattaaata ttattctatt tattggtata
     2581 tgaaatcata ttgtttatta ttttataatc ttttcatcat ataaactatt gtattctata
     2641 aactgataca tatccagctg cagaagtacc tgtcgtgcct gaaccaaatg taaaacttaa
     2701 agtaacagct gctgctctag catcaactaa aaagcttaaa cttacactta catctgatga
     2761 agtaagtgta tttactgctt ttgcaataaa gttattttga gctactccat taaagttagt
     2821 agtaattgac ataaatcctg caagtgaaag tgtggcacgt ataccgaaag atacattgta
     2881 tatccctcca actgcaagat ttatagtact acttgttgga aaagttatat tagttccatt
     2941 tataaatgat gaattaaatg tcactaatgt attattcact aaacttgaag aggacactgt
     3001 aaattgtgca ttgtttgttg ctaacactcc tgttgctcct gtcgccccgg ttggacctgt
     3061 tgctccattt gctccggttg ctccggtcgc ccctgttgct cctgtcgctc catttgcccc
     3121 ggttgggcct gttggtccta tcgctcctgc tactccattt gctcccgttg ctcctactgc
     3181 tccggttggg cctgttgctc catttgcccc tgttgctcct gtcgctcctg tcgctcctgc
     3241 tactccattt gctccggttg gacctgttgg acctattgga cctgctactc cattcgctcc
     3301 cgttgctcct actgctccgg ttgggcctgt tgctccattt gcccctgttg ctcctgtcgc
     3361 tcctgttgga cctactgctc catctgctcc cgttgggcct gttgctccta ctgctcccgt
     3421 tggacctatt gccccagcta ctcctgttgc tcctgtcgct cctgttggac ctaccaaacc
     3481 atttgctccg gttgctccag ttgggcctgt tgggcctgtt ggacctacca aaccatctgg
     3541 acctgttgct cctactgctc ctgttggacc tacctctcca tctgctccgg ttggacctgt
     3601 tgctcctatt gggcctgttg ccccagttgt tccggttgct ccagtcgctc ctatacttcc
     3661 ggttggacct gttgctcctg tatttcctgt tggtcctgta gcacctgtta ctccatttgc
     3721 tccggttgct cctgtatttc ctgttggacc tgttattcca tttgctccgg ttgctccggt
     3781 tgctcctgtt agtccggttg gacctgttgc tccagttgct cctgtattcc ctgttggacc
     3841 tgttattcca tttgctccag tcgctcctgt atttcctgtt ggtcctgtag agcctgttat
     3901 tccatttgct ccagttgctc ctttgtttcc tgttggacct gttattccat ttgctccggt
     3961 tgctcctgta ttccctgtcg gacctgttat tccattcgct ccagtcgctc ctgtatttcc
     4021 tgttggtcct gtagagcctg ttgttccatt tggtccagtt gctcccatat ttcctgttgg
     4081 acccgttatt ccattcgctc cagttgctcc cgtatttcct gttggtcctg ttattccatt
     4141 tgctccggtc gctccggttg cacctctagg ccccgtcggt cctgttggac cagtagcacc
     4201 tgttggccct gttggaccta catcttgata taaacttgga cctgaaatat cactcatata
     4261 attaatcctc cttttttaaa gttaaagtat tactctataa atattgagta ttactctata
     4321 taattatatg aatcgacaat ttcttatgtg ataatgtatc tatttgctta tatcaacata
     4381 tatgctttga ttcttgaatt tcattacttt tttgtaaaat cttttacaat tattaataca
     4441 attaaaaaac tcatttccca tcaattattt aaaatttttt tattatgtta taaaaaatag
     4501 ataattaaat tgcataaaat taatttaata ctactttaat tactttgtaa ataaaaaaac
     4561 ctcaacacga ttaataaaaa tcatattaag gcatccacaa aattatataa ttgcttatct
     4621 atcttcatca gtaacattga atatataagg aacatttcta taataatcac caaaatcaaa
     4681 cccatatcca accacaaact tatcttctat ttcaaatcca caataatctg gcactaaatc
     4741 gacttttctt ctgcttggtt tatccaaaag aacacagcat tttaaactag caggattttt
     4801 agcttttaga tgttttaaca caaaatccat agtaagtgca gaatcagtaa tatcgtctac
     4861 aaccaaaaca tcatatcctg ctatatcagt agtcacatct gaaactactt taacccttcc
     4921 agtactttct tcattgtttc cataactaga tgtagtcata aaattaactc taagtggtaa
     4981 atttatattt ctaactaagt ctgcacaaaa tataaagcta ccttttaata gagaaactac
     5041 cataagattt ttatctttat aatctttttc tataattgct cctaattccc ttaatttatc
     5101 tttaattttt tcttctgaat acaatacttc ccattttttt gtttctatat ccataaaaag
     5161 acctccaatt gtaataatcc ttcttaattt tataagagat tgctcacttt ttcaatactc
     5221 ttattcaata ttagtcaata ttattgagtt tttatgttca ttcaacaatt attaacaatg
     5281 tatcttatat tttaagtagt tcatatatcc acactaaatt acatactata tattttagac
     5341 aaaaaaagaa aaaacttgca ctaacaagtt ttttctatta tacataaatt tatacataat
     5401 catattttat tagaggatac taattaaatt tatttatgct atttttgtta tacctcataa
     5461 tacaaaacat attataaagt actagtcaac tttattcata tcattcatta catttaagat
     5521 tatctcatct gttatagaca tacctttgtc acttactcta cctaagtttt gtatactttg
     5581 ctcaacactt gaaccaacta taccatttag tggtggtaca aaacaatctt gcttagctat
     5641 tatagcactt tgtatagctg cagatgctgc agaagataat tttaatgcac aaccagcttt
     5701 cgcaccgtca catatcattc cacttaagtc agctatcata ttttctatag ctccttctat
     5761 ttgcttttca gtaccattca taagccaaga gataccagca gttgctccag tagaagcagc
     5821 aacaccacat ccacatacag cagataatct tcctgtatag ttcttaatat aaccagttac
     5881 tagatgagat atagctaaag cttttgctag tctttcatca gattgtggga attttttatt
     5941 ataagcaacg attggaagaa ttgctgttaa tccatgattt ccacttccat ttgaactcat
     6001 aacaggcatt tttacccctg ccattcttgc atctgaagct ccagcagtta acatcattgc
     6061 ataatttata acatcattac ctaaaagacc ttcctctata gactttttaa ttccataccc
     6121 gacaccaata ccagtttttt gttttaatcc atattcagcc atctcttcat tcatttttac
     6181 tccatctagt aaaaattcta tatctttaaa atcaatttct tctacatttt ttattaattc
     6241 ttgtatagtt actgtatcca ttaaactttc agctttttct gccgcatcat ttgaagctga
     6301 tacttttggt tcattgtcta ataatacttc tccatctttt tctaagaacg taaaattatc
     6361 atgtttagtt cttattctca ctttagcaat atgatttttt ccttttaaca caacttctat
     6421 aaatactttc tctcttgtat cagcaggtgt tattgatagt ggagtattat ccatataatc
     6481 ctcagctatt ttaacttcct cttttgttag agtttctaac acacttaatc cattttcaga
     6541 atgtccacct actataccta gagctgctgc aatttttaat cctaatcttt cagtacctgg
     6601 tatacctacg cacataccat ttttatagat actaggacta actaacatac gattttcaac
     6661 tatttcttct cctaataatt cctttgcctt tgcacatgct agagctaagg ctactggttc
     6721 agtacaccct actgctggtt taacttctgc ctttaacatt tccactaatt cttttcttat
     6781 atctctcatt atatataaac ctcccaatta agtttagatt tagtactcaa ataattaatt
     6841 aaataatttc ttatctatat ttatagcaaa atacatgcca tattttttat atctttttat
     6901 atttttagtc ttatattcta taaccattgg tatgactgcc tctatttatg tatttttttt
     6961 atttgtatag agtatttata ttctttaaaa tggagaaaca tatgacaatt tcgcaaaaag
     7021 acaaaaaaaa gtctcaaaat gagattctat atcattttga gacggctcaa atgtattatt
     7081 ttttaactta taaaaaccat tttttaattc ataaaaaaag attctgcaaa acacttatag
     7141 tataagttta aagctttctt taaagttatg aatttagaaa aatttaaatt ttatatagct
     7201 ttttattata ttactatgaa attatattgt atttttcaat ttttctatat aatgtagctc
     7261 ttgatattcc aagtgcttta gctgttaatt ctttatcttt tttataatct ttgtacttat
     7321 ttaaagcttt tattatctca atcttctcta gttcatcaag tggaattatc ctatcgcttt
     7381 taacttctaa ctcttctaca gaggtattct taattttttg aggaattaca ttcattgtga
     7441 ttattgaaga agaagacata ttcacactat attcaataat attctgcaac tctcttatat
     7501 tccctggcca cttatattcc atcatagcat caacaaccct gctatctatg tcaataacat
     7561 ttttatctaa tttttttgaa tactctttaa ccatatgctt gattataagt gggatatctt
     7621 cttttctctc tcttaaactt ggtaatttta taggtataac atttaatcta taatataaat
     7681 cttctctaaa agtgccattt tgaaccattc tttctaaatc tttatttgta gcagcaataa
     7741 ttcttacatc tattgaaaca tttgatttac ttccaatttt attaagttcc ttttcttgta
     7801 atactctcaa taactttgac tgtaaatgca aactcatatc tcctatttca tctaaaaata
     7861 tacttccctt atgagctact tcaaacattc caagctttcc acctttttta gctccagtaa
     7921 aagctccctc ttcatatcca aataattcac tctctaataa attgtctggt atagcagcac
     7981 agtttacagc tataaaagga ttatctactc tattgctatg gttgtgtatg gctcttgcaa
     8041 atagctcctt acccgttcca ctttccccag taataagtac tgttgatgtt gatttagaag
     8101 ctattagggc ttccttttta gaatttctta tagctacact ttctccaatt atgttttcca
     8161 attttattct ataatcttta ttcatcttat tgtagttttt tatagcatct ctcttatcta
     8221 taaaatcaat aacatatccc tttaactcat tttttaatac tattttattg atgttgtata
     8281 ttcccttcga atcatatccg tatcttttat aaaaaaaact acaggatttg tccttcttaa
     8341 agttatttat agaaggtttc tttataaaat ctaattcgac aaatatgttt ttgccagtta
     8401 tactatcttt tatattgaaa agctctttaa attttgaatt atatttatca atttttccat
     8461 ccacatcaat agacacaaca gctttgtcca tattgtttaa tagtgtctct aattttttct
     8521 tttctaattc aagctcataa gttttaattt gtgcttttaa tttattagat attaggtctg
     8581 ccattttgcc taaaaagttt ataagaccac ttttattatt ttctataatt tgtgcttgtt
     8641 cttttgtaaa ggctataagg cctataacac catgagaatc gccatcacat ataataggac
     8701 aacacacctc tgcaaactct acacaagccc cacttttata gcattcccta catatatcac
     8761 tactctttgg gtcatcaatt agtattgtaa tctgttctgt aagtgatttt ttaaaagccg
     8821 tatatttatc tactttctca cctattttgt ctatatatac tcctgtacct gcaatcctaa
     8881 ataactcctt atttactata gttacatcta tattgagtac tgatactata gcttcagcta
     8941 tattttgaat atcagatttt atatattcta aacctatcat aatcatcatt ccttattttt
     9001 ctttagcata agtatttgtc ttatttcttt aagaatcaag tatatcttat ttaaagtaaa
     9061 ttggattgac atcaggatta caaagagcat aacaattatt attaactcat aatttatttc
     9121 catctaaaca tctccttata acaaaagact aggcttaacc tagtctttta tattatatcc
     9181 atatttatat tttaactcat ttatcttctt tttcccacat aaatatattt taatttattt
     9241 gactctttaa tcataccatc aaagtttaat cttgaaaata tattaaatac ttcatgtgga
     9301 tagtgaatct ttgcaacaga accacaaaat ttatgtttaa gatagtttaa cttaactttt
     9361 aaatttttta aatttaaatc ctctaatata acctctccat tgccctttaa cactctttgt
     9421 atttcagatg aagctttttc acaatctgta ataacattaa attggtcaac tattattatc
     9481 ttgttgaact gattatcatc aaatggtaga aactctaact tacctttaac tacattgcaa
     9541 ttttcattat acactagaga ataacagaca tcttcataat tactattctc cagtatagtt
     9601 acagaagttc caagacctct caatctcttg cctaggtttc ctatatgacc aacaagcaat
     9661 attttatcac ctacattata ctcaattgta tccaaaaaac attctaattc atcagatgta
     9721 tatttagctt taaccggctg tttatttatc tgacataata tgcttttcac aatgcttcac
     9781 ctcttcattt cctcaattat aaattatgta cagattacat tataataaat ggcgagcaac
     9841 tattcaagag atatttcatt agtatttttt taaacaatct ttatacattt caatatgata
     9901 ttataccaaa tttattagga ttttattcat aaaaatcagt ctatttttta tgtttattca
     9961 ttgttatttt catccaattt ttttattttc gatatggata cttcatatgc catttttttg
    10021 accacattat tttcatctat ttttttctca tattctctac tttgaaccct accccaaagc
    10081 tgtattctat caccaacctt tagattcttt gcaaatttag catttctacc ccaaactatt
    10141 gatggtatat aatcagattt attataaggt ctatttatag caactaataa atcggttatt
    10201 tcccttccta aaggtgtctt cctatacaca ggttccttac atacatatcc atctaaaaat
    10261 atactattag ggtctttatt ttcctcgtct atgcttttta tttctctgac aaacactgta
    10321 agcactaatc tatttttatt atttaatgtt ttgttatatg atcttaattg gcctacgaca
    10381 ttgactaaat tttgtttatc aaggtcaata tcttggagaa gtctttctga tacagtcatt
    10441 ggaagtatat caaaagaatc gcttagtctg tttattttta ttttcatatt ataaaatttt
    10501 tctccaaata tctcatggct aaattctagc ttattgtcta actcccctct taagtttact
    10561 acgttattct catctttaac agctatcata ttttatccct ccacaattgt taattcttat
    10621 atttctggta tcagcttata taataaatat atttataagg gatgtatttt attacaaatc
    10681 tttgattgct gttcaaaagt ttttatttag ttataaattt catttaatat ttcactttta
    10741 taattataaa attattatct ttttgtacca catatactaa ttaaactacc tatttcagtt
    10801 ttgtattaat tataaaaatc ctattataca attaataagt catatataat ttaaatttat
    10861 tcactctata taagcaactt caacgaatta aatttattca aataattcag atgaatattg
    10921 agtcattata aacttatttt tcttaattat aagttatatt agacttatta caggttatat
    10981 ttttattaat ctgtattaat atatgaacat ttattgaact tattgattat aaaatttaaa
    11041 tatttagctt taaattatgc tttattcttt aaaaatacaa cgttttttac attaaatcta
    11101 ctaaatcact atatatatta cataattggc atgttaattg ctttatatta atttagtaaa
    11161 taaaaaactg ccctaaaata ttaattcaat attttaaagc agtttataat ctttattatt
    11221 agctgtaata tttaataaac actaagtagt ctttaactaa gcagtctttt tgtttttatt
    11281 tgcagccatt atcattgtag cagaagtata agctataact actattacta atgcttttaa
    11341 tatatccatt ggtagagttt ttactatata tgcagctacg aaaactccta ttaaaccaca
    11401 tatagctatt ataactgatg cttttttagt atatgcatct tcttttatga atttcatact
    11461 tgcaactggc attaataatg cacaagaacc cataactatt gggaatgcaa cttttgcaga
    11521 cattcctaag aaataaacca ttgccatacc tggagcatat agacctatac cagctgtcat
    11581 taaagctcct agtataaagt tacctattac acctattact aatttaacac cagtaagacc
    11641 taattcattt cctccacctg gtaatacgtt aatccaagga tgacctaata acattaatat
    11701 tgctgttaat gctaaagtta cacccataac aagttgtatt tttctctcgt ccatcttagc
    11761 tattattcct gcacctatat atgaaccaac tgctgctgcc acaaccatag atactaaagt
    11821 aacaccatca actggtatga ttgatgtaaa tatgaatgct tctgtaacaa ctggaatagt
    11881 atgtgctacg tttaatgtac caggcatttt tttatctggt atatttaact ttaaagcctt
    11941 tgacattgct attgttggag caaatgaccc tattcctaat gtatcaaaga agtctgttat
    12001 aaatcctgtt acagcaactt ttggagtact ttgttcttct agtttcccct ctttgtttgc
    12061 tttagctacg tctttaccaa acacaactgc aaagattgct gcgaatacta catataatgc
    12121 ctttaagatt gctaccataa tccatcctcc tattttttta ttttttcata tattctgaat
    12181 cttatagcct aaaagctata gaatagcaac cgacaagtgg ctactattct attttaattt
    12241 cctaatttat ttattactta tttaagaata aatccatgtt taagtgggtc ttcttcatct
    12301 attacaaaat gattaaatcc agttatataa gcagaaccag ttattttagg tactacagca
    12361 ttgaaatctg caactttagt ttcttcaact atttcacctt tgaataaagt tcctaatata
    12421 ctttcatata cgaatttttc tcctactttt aattcacctt tagcatgtaa agtagctaat
    12481 ttagcacttg ttccagttcc acatggagat ctgtcaactt gaccttgacc aaatataact
    12541 acatttttgt aagtagcttc tggatgagtt ggctcatcat atatttcaac taagtctaca
    12601 gtttttatat gagctaaagt tggatgttgt atttctattt tctcatttat tatatctcta
    12661 agtttcatag ctagttcagt taatttacca gcattttgag gttcgatttt taaacctaat
    12721 tgacttgcat gtattatagc aaagaagctt ccaccaaatg atatgtcaaa tttaacagtt
    12781 ccaacacctg gtaagtcaac ttcaacacct tctttatata agaaagctgg tacgtttaag
    12841 aatgatactt ctttagcttt tccatctaca actgtaacgt ctcctcttat tattcctgct
    12901 ggagcttcca taactacatg agttacaggc tctactgctg gaactacacc tgtttctata
    12961 gctgctgtca tagctcctat tgtaccatgg ccacacatgt taaggtatcc gccaccatcc
    13021 atgaagatta ttccaaagtc agcatctggg caacaaggtt gagtcattac agaaccaaac
    13081 atatcattat gtcctcttgg ctctaacatt atagcagttc ttaaataatc tagattttcc
    13141 tctaaatatt cttttttctc aggcatagaa tttcctttta tgttaggtat tccacctaca
    13201 actattctag ttgcttcacc tgctgtatga gagtctatag cttgtatact tctgctaaat
    13261 ttcatatcaa attccccctt aggtttattt tgcgtcttta cgcattttta attttaggaa
    13321 agccaatgct tttttaacat caacttcatc catgtgattg tctccaacta cttctgtttc
    13381 tatgtagcct gttgtctttt tataatcaat tatggtagct ttatccaaat atggattggt
    13441 aattactaat ccatctgctc ccataatagt aagacctact gtaggtatat ctgattttac
    13501 aaactctgct atagcatttg taaaatcaat gtgctggttt cctgccatat ctaaagttat
    13561 aatcactcca tcaggtcgca atgattcaat ccatcttcca agtctagttg ctaaaaatgt
    13621 tttccattca ttgtgctctg atgtcccaac tacaaccact cctaacaagt ctatgtcaga
    13681 atcattatct atcaaatcta gtaacgggtc tctaaatata tgaagtgatg tgtttttcat
    13741 tgatgtagaa attcccacaa aactcattcc cttacttaaa ttttttatcc atgttttctc
    13801 attttaagtt ttaaaaatgc caaagctttt ttagcatcta tttcatttgt gttgttttct
    13861 ccaactactt ctgtctcaat accttctttt gatttgttca tatcaactat ggtatccata
    13921 tattgattgc ttacaacaaa cttagcttga gtcccattaa atgtaactcc aactacaggt
    13981 atatctcttt ttcctatttc ctcaaatgtg ttagcgtagt caacatgtga gtttccccaa
    14041 ccatctgatg aaactatagc tccatctact ctcatagctt ccagccaagc ggccgttctt
    14101 tgtcccacaa aggttttatt ttcatttcca tctggagttc ctactactat tactccaagt
    14161 aaatctacat ccttatcact ttcaactatg tctaaaagtg ggtctctaaa gtgatgaaga
    14221 gatgtttctt ttgttgaagg tcctattccc ataatatcca cctctcttaa gtcatagctc
    14281 taagggcacc atctctgtat tcattaggag atataatcat aggtacattt cccatatcta
    14341 taattgatgt tcctccttca aatccactag gttcctttga gaataactga ttgtcataca
    14401 tagcaccttg acctgctatt tgttttacta tgacaacctt ttttgcattt ggtcgaattt
    14461 tgtcaaaata ttcacgaact tgagtagcat ttcttccgtc ttccattttc aaagacgctc
    14521 ttatttcttg tataaaatca tcacatgctc tgaatgctgc aagtggaagt gttctttcaa
    14581 aaggtaaacc tccctttaaa gttacatcta catggattat ataatcttca actgatggag
    14641 ttccatatct cccaaatacc atttggtctt tcaaaattcc ttctgaagaa ccaaattcat
    14701 gcatttgatt tccatcttca tctgcaccag ttaacattac atatacaccc gttaaagtat
    14761 gtgtaatacc ctctcccagt ctgcctaaaa cttttgttga tattggtata atgtccataa
    14821 tagtattaat ttctctgtca taatctccag gttttataat gtctactttt atgtctgtta
    14881 ttaactcttc tctttctttt atttcatcta tacttgataa atctattgta agtacatctt
    14941 tctttataga agtttttgaa ccgaaattaa cttcattcat atgaaacggt tttataacaa
    15001 gtcttctcat tattttttct tccataatat ccacctttgt tcttaaaacc cctctcctaa
    15061 ccgtgtagga gaagggttct atattttcaa atataaatta cattttaaac gtgagcttta
    15121 tattcgtatg gtaatggaac tatcttacca gcagatggta ttgcaactaa ttgctctaat
    15181 gtatctctta atatatgtgt ttgcatttct atattatgtg gttcaccagc attagcaccc
    15241 attggaacta atggagcaac tgctctagga gttccgtttt gtctaactac tggaggaaga
    15301 gctgctatta ttattgtagg tattccagct tcctctattg ctctctgcac gatcacggca
    15361 gttctatggc aagtacctca gccagctgtc ataactacac cgtctactcc ctcttcctta
    15421 agtttagcag cgatagcagg accagtttct tcagtgaaga catgttggtt tcctccacca
    15481 cccatgaatg catagtgcat aggagctact cctttgataa atccttctgc agctaattca
    15541 tgtaatctat ctatagggaa catacagttt atatctttgt ttacatctcc attgtcatat
    15601 ccaccatgtg ataccatcat ttcatcaact gtagctgtat taggtatagc tctaaatgta
    15661 gtatctcctg ctagattaaa tctcttgtca gattttaaat gaacaccagc tgctgtagct
    15721 aaagctatag tcatatcttt taattcttta gttacaggag tccaaactgg aggaggtgtt
    15781 attggaacga atatttcaga ttgaagtcct tgtactgttg taaggctcat atatttcctc
    15841 tcccttctat tttcaaacga ttatttatta tttttcttct tgttttgatt gcatttctgc
    15901 ttgtttttct ttttctctcc taatattttc tacatactct tgattaggct ctggacttaa
    15961 tacctcagga tagcttagca tgaatccaac ttcttgacct atcttaagtt cgtagtcagt
    16021 tataagcatt ctattaggta ttttaaattg tccaagtcta ccttttaggt ctatagtcac
    16081 tccaccgcct ttgatgtcaa ctataatacc ttcataaaaa gtctctgatg agatatattt
    16141 taacctatcc attataattc tacctctcta tactgtttta aacttggatc taaatttatg
    16201 ttattgtcta aatcttagtt agtatctaaa ttttagtttt cgtctttttc gtatatttct
    16261 cttctcttct tactcattgg tagagattgc tcattctctt ctaatactat tttttctcct
    16321 gtaacttttt ctatagcttc tatgttattt aatttaacat ttggattcca ttttctttca
    16381 ggagctttaa cttctacacc ttctatagca tttttaagca tagccattat tctaacagca
    16441 tcttctggag ctaaagtgtt gttagataat atttcattct ctataccttg cttagattta
    16501 ttgttgtcta ccatgtgagt catgtattta ttaccaacaa ctagagcacc ttgaacagct
    16561 gagaaactta caccaactac tggtatacct ctcataccta tttgctctat gtgagatgcg
    16621 aaatctatat ggttgtttcc gaaaccttca gtagttacta cagctccatc aacttccata
    16681 gcttcaacta acatacctaa tctcttagat acatagaatt tctcagcatt tacttgtgga
    16741 gaaccaacaa atacaacacc tactaaatct atttcttcgt cttccatagc tcttattact
    16801 aatggctctc tccagtaatg tcttgacatt tcttttgatg caggccctat acaagttaat
    16861 gcatggatac caccatctaa tacttcaagt ggagataata caactggcat gtttcctaag
    16921 tcaacgtttg gttgagctcc taatgtacca actggctcaa ctggtaatat taggttatca
    16981 tgcattgcac cttgtcccat tatttctttt ataacaacaa ctttcttttt accttctctt
    17041 ctgtattgct ctattacttc ttcatcaact actaaagagt tgtcaacttt ctttaatgct
    17101 tctcttattt cttgagttac atagtcaaat gcacggtgag cagctaaagg tcctggtctt
    17161 tccatgttag ttcctgcttt tattgttact tgacctttga tgaatatttc acctttgtca
    17221 gcagcacctg gtctacccca cattatagta gtatttaact caccttctga agaaccaaat
    17281 tcacctattt gaactccatc ttcatctgta ccagttaata ccattacagc tccatctata
    17341 actctagtta tacctgaacc taattcgcct tcttctttag tagcgattgg ttgtatatct
    17401 aatacagctt cactgtaagt ttcatattta tcaggagtta ttatttctaa cttcatatct
    17461 acaactaact cttgagtttc attagcttct ttacatattt cttctgcgtt tctgatgtat
    17521 aaagtagttc cttctatttt agtttcatca gcaaattcaa ctttatctat tttaaagtgt
    17581 tttttagtta agcttcttaa aagtttcttt tcttcaactt ttggagctac ttctgctgct
    17641 gcacttgcca ctggagcagc aacgtttgct actggagcag caactcctgc ttgaccagct
    17701 actgataaag gtatctctaa gcttatgttc ttaccttcac ctatgtgtat tttaactgtt
    17761 tcacctgcaa ctcctgtgct tactggaact actgctgctt ctgatactgg agctgcttct
    17821 tctactgttt cttctactac ttcttcttta gcctctcctg ctttgtatcc ttctacgtta
    17881 tctgtagtca ttggagaaag tgcatctaaa gtttctttta acttagctcc tagtacttga
    17941 cctatagtta atccattttc tggtattgtt aataatccag aatcctctaa gtctgcaaat
    18001 attgctggat cttctaagtt ttctggcgct ataattgttc ccgcttcaaa tctacaacaa
    18061 caaactgctg ggtcatttgc atgggcttga gctgtttcta aagttattga catagtataa
    18121 aatacctcct tacattattt tcttatttat tattttaaat ctcaattcct caacaggtaa
    18181 ccccttaact gagaaattaa gtaaattaaa acctacataa tttgttatga ttaatattat
    18241 ttttttctca cttaaagtca ctttatatta taagcaattc ctatgccaac ttattaacaa
    18301 aaagattttt tctataatag attcttcatc tatcgctatt tttagccaaa tattatataa
    18361 atatttattt aaaatatgtt attttttgta tttgtaaaca ttttctcaaa caaaaaaagt
    18421 gtcaattaat caacactttt tcattttttt taacacatct atatacacaa cacttataca
    18481 agcgttggct ttactaggtt ttaaattaaa gtttatcatt ttgtcaaaat ttagtcatgt
    18541 gtcatatttt agacacatct attttgtatt ggtctatctt ataatacaaa gttgttctgg
    18601 gtatatttaa tatcttagct gctttagctt tatttccatt agacatttta agtgccttgg
    18661 ttatattctt tatttcaatt ttttgagttg ccttcgttaa atctaaagga tactcttctt
    18721 cttcagtact attatttgta gaatccatca tataacttgg tacatcatcc acatctattt
    18781 tagaattttg tgacaataca acaatatttt caatcgtatt ttttaattct ctaatattac
    18841 ctttccatct ataattctga aatatatcta ttacatcttt gctaattgta agaacaggct
    18901 tattattttg tttacatatc tcctctaaaa agctatgaac caataatcct atgtcttctt
    18961 ttctctctct aagtggagga atctttattt caacaacatt taatctatag tataaatctt
    19021 ctctaaattt ttcggccttt accattttac tcaaatcttt attggtagct gatattattc
    19081 taggatttat ttttattgtg gtatctccac caactcttct tatttctttt tcctgtaata
    19141 ctctaagcaa ctttgcttgc atactaagag gtaaatcggc aatttcatct aaaaatacag
    19201 ttccatcttt tgcaagttca aatataccta ttcgaccctt tttacttgct cctgtaaacg
    19261 cacctgattc atacccaaaa aactcacttt caaataactc atttggtatg gcactacagt
    19321 taacaggtat aaattgccct tttctctcac tataatcatg aatagctctt gcaaatactt
    19381 ctttacctgt accactttcg ccccaaataa atatactact atttgttcta gccacttgtt
    19441 ttgcaatcgc tttcgatttt tctagtttat aacttttacc taaaatctta tcaaaactac
    19501 ctttagataa atttttgact tcgttcttta gatattttaa tgtatcattt actttttcaa
    19561 gttcaagagc taatatctta gcttctgtaa catcaacttc tgtacataca acaccgataa
    19621 attcttcttt ataaaatata ggatttgcat gaactaatgc atacatattt tcttttttat
    19681 ctgtaaaata caagtcactc attccaactt tactatttag tactttttct gaaatagtat
    19741 tttccaaaaa ttcattcatc ggtcgaccaa ctatatcttc agactttata tcataccttt
    19801 cctccataaa cttattccac aagataacaa caccttcgtt atttatagca caaattcctt
    19861 ctttaatttg acctataata tacttcaaag ttaatccata atcttctaaa tgcatatata
    19921 gatagtccct aatgtgctct tgttttagaa ctccaataat tttattatct ctaagaacag
    19981 gaagaatccc tatatttttt aatatcatta tatctctaca ttcatctaag gttaaacctt
    20041 cgttgacata tattacatcc ttcttcatta taagttttac tggttgacct tcatactttt
    20101 tatgcatctc ataaagatta tgtatatccg tcatggatat aatgcctttt aattggtcag
    20161 atgaatctat taccattaga gtttttgtgt tgctttttat catttctttt attgcatctt
    20221 caattcttgt gtcttcgtct atagttgtaa attttgtatc cattacctct tctacttttt
    20281 ttacttctgg tatcgaaaac ataaagtccc ccctttatag tagtacctca tcaaaactta
    20341 tttatatata tttattctag catattataa taattattta ttaaataatt attattaaaa
    20401 tttattaagt aattagcatt taaatttata taatcacttt aaaatttata attaaattta
    20461 tacaaatgaa atcaaatgaa ttataccctt agtatattat tttttcaata ctattttcac
    20521 cttcaaaaca tttttctatt catcaaacaa ttaatgaatg cctgtatcca atcataaatt
    20581 taagaatata attaaaatag atatttttaa acaaactata tttgcatatt atatttacat
    20641 aaaaaagccc caaaatgact tataaatcaa tttgagactt tttattttaa acttaataat
    20701 aatctagatt aatttctttt tattttacat tgatacgcta atccacaaat tgcaatgaca
    20761 ctaataaata catatgacat tagctgagtt tcatcacctg tttttggtga ttttactatt
    20821 gtatcatctc ttgatagttc tggagttttt tccactgtat cacttactgg tggtactggt
    20881 ggatttaaca ctgtatcatc tgttggtggc actggtggat ttagcactgc atcctccatt
    20941 ggtggcactg gtggatttaa cactgcatcc tccgttggtg gtactggtgg atttattatt
    21001 gtatcatcca ttggtggtac tggtggattt attactgtat catctattgg tggtgatggt
    21061 tttggcttat gtccatttgt atcatctgtt ggtggcaccg gtggatttac aacatcatca
    21121 tctattggtg gcactggtgg atttacaaca tcatcatcat ctgttggtag acctatatta
    21181 aagttaactt cttgaccatt ctttttctct attgtataac ttaataaatt ttgcttacta
    21241 gatggtaatg aagatgaatg gtctttttgt cctaaatcaa gcactgcctt ataatattga
    21301 atagcttttg gaaaaatata atcataagat acagcagaaa tattagcttt ggcatctggt
    21361 tttccaacac tcttaagttt aaatttctgt tgtgttgaaa tttctacttc atctgtacct
    21421 attatattac catctccatc ataagcagtt actccatctg gtagtcttaa ctttactaca
    21481 ccactataac ctactaaggc tacagcttct gtttcataag taccatcttc atttttttca
    21541 aagttgatct tagttaaacc attactcaaa ctaggttttc ctgtatcatt tggctttaac
    21601 tcttcacgac ctgcttttaa caatgcttct aaataagctt ttatatttat agctacttct
    21661 ttcttcttct gatactccgc tctttcctct tcagtttttg ctctttctat aagtttatca
    21721 caaaggttta tagaaccttg atactgctta agtctttctt gttcatccat ttgtccaaga
    21781 ataatccaaa ttgcactttg agtagctgag taagtcatca attcattttc ttctccacct
    21841 aaattaaatt gttgcttata tccaaatcca tcaaattcag aacctgcata tagtatagat
    21901 ttaactgctt cttcattttg gttttcttga ccattaaaat cttctgctgg taaatatgga
    21961 ctctttccat tactacttgg tggtcttaaa tgattattgt aacaaaatgc agtttgctct
    22021 ccatcttcac cttctattac atatttgtcg tcttttgagc ttgctcctac aagacccttt
    22081 attacatagt caaaagttaa agtctttgta atatcatcaa atcttaaatc atgataaggt
    22141 ctatctgaac catctatttc ttttagtaaa caagaatttt ttacttttgc ttttttgtca
    22201 taccataagc taataaatga gtcttttgaa gtaaaaactt ggttaatttc tgattgttca
    22261 tctgccttta catcttcttc atcttcccaa aagttatata ctattttatt tatttgagat
    22321 aaagtcatat caagaatttt atcaatatct tgttttaaac tcatttcctc tataactatt
    22381 tcttcttcca atggtttttc ttcttctgga gtttgctcat ctaatggttt ctccccatct
    22441 ggcatctgac catctgatgg tttctctaca tctggcgtct gactatctga tggcttctct
    22501 ccatctggca tctgaccatc tgatggtttc tccccatctg gtatctgacc atctgatggt
    22561 ttctctccat ctggtatctg accatctgat ggtttctccc catctggtat ctgaccatct
    22621 gatggtttct ccccatctgg tacctgaccg tctgatggtt tctccccatc tggtacttga
    22681 ctgtctgatg gtttctcccc atctggtacc tgaccgtctg atggtttctc tacatctggt
    22741 gtctgaccat ttgattgttc ttctccatta agtattgtat cattgctagt cacttcgtca
    22801 gcataagata ctattggtgt aaatgcagta aataccatac taaaagcaat tactaaactg
    22861 attatacttg attttttaat ttttgttttc aaaattctcc tgatactaaa aacatatatt
    22921 gtattcactt aatataatta aaattattaa atattatatg aatcttattc aataatacat
    22981 ctttagtgtg ttcaattagg gtcgttactc ctaaccagtt ctcctatgaa cttcttaata
    23041 tttctattaa gcacagacta tatcattacc taaccataaa ttaggtactc cccatttccc
    23101 cacacttgta ggtacgagat ttctctctag tcgttgaagt ttcttctttt cgaagcttac
    23161 ctgctgatta tccattttca aggcacttag gatttaacct tatgctatct aactaatttt
    23221 ttctactttc gtaacctcaa gtgcttatta aatgcacact ctatcacact tatccttatt
    23281 tcatgattat gttgtggttt agttagcttt aggaacttcc agcaattaaa ggagttttgg
    23341 gcagatatct gccactctac actcgttatg aatgcaggga gcatttcaaa aatatattta
    23401 tatctatctt ctattaatta cttatttatg tatttatttt atatattttt gacaattaaa
    23461 agttactcct atttatattt atagcaggtt gcactactaa ctccatatat cttttaagtg
    23521 cccaggttta agatatactt cacagtttct ataaataggt ttttaatttt tcttttttaa
    23581 ctttttaagt gcactttttt aacaactcaa taaaatataa attagtatcc tagatactta
    23641 tctaataaaa gacaaaaatt agtttttata ataaaaaaga tactatagag tatcttcaaa
    23701 tatcacaaaa accttttact ctatcggata gttgacttaa tataatatgc atattaatac
    23761 aaaccacata cttgagtatc attatttttg tccaatatta attgtaatag ctattgttat
    23821 cattatacaa tatctagcat attttgtcta ttttttccat ttattttaca atatatatat
    23881 tgccctcaaa atacattaaa aaacatcctt agaagtaact tttaagtttt acttctaaag
    23941 atgtctaact tctatttatc tattatttta tttttaatct tacatcacct tttattcttc
    24001 ttattaatgg gtgattaact gttctcatta catggtcagt aatatgatat acacctaatt
    24061 ttaattttgg tgcagaaccc attactgtgt tactacagtc agtacagttt cctattaata
    24121 taacttctgc tccagctttc ttaaattcaa tacatttttg agcttgtcct ggacagtgtc
    24181 ctggattttc acattttaat gcacctttaa tttcttgagc ttgtttacat ttttgaactg
    24241 atactatatc agtaactccc attttagttg ctatatctct cattctttct tcattaggtc
    24301 cacatgcaca aactaaaaga cccatttttc tcttttcatt aacaaatggc atagtaacta
    24361 ttataccacc actagtttta gttattggag catctaaagt agtagcttta ccagtgaaag
    24421 gtcctcctag gattatttca ccatattcac cttttattcc accagctctt tcaattaatt
    24481 ctccgacagt tgttccaatt ggcacatctt caaacactat agattctttt ccactgttta
    24541 attgaccaac tacagttata tttttagata taactggtct tttttgctca acagcctcta
    24601 ctattctagt tagtgtttct acgtttatta ctactgcatt agcctctgaa ggtaattgag
    24661 ttggctcaag taattttcct agaacgtctc ttactattgc tctctcttct cccattgggt
    24721 acatatcaac taattctgca acttctatgt tgtctcctgg ctttattact tttttgaaag
    24781 cttctattgc ttttggatgc ttacttttta ttgctagcat accttttcca gcattagtaa
    24841 cttccatagc atattttata ccttgataaa ctatttctgg tctttcttct atttctttta
    24901 tattatgagc taataaaggt tcacattcag ctgcatttgc taatattgtt ccaccattta
    24961 aatctatgtt taattttaca tgagtaggga atcctgctcc acccattcct actactccag
    25021 cttctttaat taagtcaagt ataccttctc cttttaatgg ttcaaaagta tcttcttgta
    25081 cttcatcagc ttcaattact atcgcttggt catttatttc acttattttt ccactaacac
    25141 tggcataaat atttgcccct aatccagttg gttctgcgat tagagttcct ttttttacta
    25201 catctccaac acttactact ggcttatctg gaccaccaac gtgttgtttt aataaaatag
    25261 aatatagttt gttcaactag tacgccccct taagtatatt aattttttta taagctgttc
    25321 aaataatgtt aatgctattt ttctattata aggtcttaac atattgttta tttctataga
    25381 acatatcgct tattaacaaa gcaatttcta tgccaacttt taaacaaact tatacccttt
    25441 ggaaatactg tcttacagca ttcattaatt cttctaaatt tttaaaccca tcaaaaaaaa
    25501 gtcaattatt agacactttt ttaatcaatt taatctataa ttattgatat tgcatacatg
    25561 tataaaaagt gtcaaaaaat agacaccgtc tttttatcga cacttttcta acatatacta
    25621 tataatttat cacaacttta cttaaaatat acatttatta cttattaatt cttagttttt
    25681 tgcactccat tggaatcaac tacataatta tctttataca acaaatcaga tattttgact
    25741 agactgtatc catctttttt tagtcgactt attatagtat ccaaatagtt atctacatca
    25801 tttatattag catggaataa aactattgaa ccaggttgag attcttttat tactttttca
    25861 attacatgat ttggtccaag ctccttccag tctatagaat ctacatccca cttaattact
    25921 ttataaccta aatcactaca aatgtccata gctttattgt ttacgtcccc aaaaggaggt
    25981 ctaaataaat tagtcctttt tcctgttata ttatatattt tttctgatgt agtttctatc
    26041 tcttttgtta tgtcttcttt tgatatttcc ttcaaattgg catgagtgtt tgaatgattt
    26101 ccaatttcat gtcctttttc atctatagct tttacaattt cttcattatc atccacccaa
    26161 ctaccaacta aaaagaaggt agcttttaca ttatgtttat ctaaaatttt taaaatatca
    26221 tccatattat cagttcccca tgctacatca aaactcaaag ctattttttt ctcatttgta
    26281 tcaactttat atataggcat ttttgaattg tcagatttag aacatatgta ttttattcca
    26341 taaacaaaaa caaatattaa cactaataat aatgaaaaaa ataaaacact atatatcaaa
    26401 gctttagtcc ttttaacttc tcttttcata ctattccccc tttgaaataa tttcttctat
    26461 atttaaaatt tatttttttt cagctcaaaa aagtactgta atatttaatt tataagacaa
    26521 taactaaaaa aataaaacct atattgacct aattaaactc tctaaaatac tcatttattt
    26581 aattttttta tattttttac atttttacct ttatttttct gtatatatta tttttatttt
    26641 ggagaaatta gtattaacat cacataaata aaagtgttgt tagacatcat aaactaatta
    26701 tttgaggagg aaatttacta tgtcaaattc aaacagaaca gtagttccag aagcaaaagc
    26761 tgctttaaac caaatgaaat tagaaatagc taacgaaata ggtttatcta actatgaaaa
    26821 catagacaaa ggtaacttaa cagctagaga aaatggatat gttggtggat atatgactaa
    26881 gaaattagtt gaaatggctg aaagacaaat ggctggaaaa taaatagtaa attttgacac
    26941 ctgggtatca acagggctgc taattagcag ccctgttttt ctatatttat ttataaaatt
    27001 gtttttatat gaattattaa agattaataa tacaatacaa attgttcttt taattttgta
    27061 caaattagtt taatatatta tatatagaaa tagtttgacg gaggatgata tttatgtttg
    27121 aaaactcgtc tgaagaatta gcctatcaca aacttttaat tttatatata ttagaaaaaa
    27181 ttaaaatgga tttaactaat tctcaaataa ctcaagtagt attagagact gagatgatga
    27241 attatttttc attacaacag cttttatctc agcttatgga atctaagttt ttgactacat
    27301 ataaagactc tgacagagaa tattatgctc ttactcaaag aggcgtagaa agtctagaat
    27361 acttctttaa tcgaatacct actagtgtta ctgaaaaaat agacaagtat atagattcta
    27421 acaaagaaaa tctactagca gatactcaag taaagtctag ttttgtaaaa caaagtgata
    27481 atgaatttat tgtcaacctt agagtcatag aaaatcagtc taacttaata gatttaaatc
    27541 taaatgtttc atcagagaaa caagcaaaac ttatttgcaa taactggaaa aataatgcat
    27601 cttatatgta tgccgaagtt atcgatttac ttataagaga catacattaa agcctacaaa
    27661 caaattatag ttgtaggctc ttttcctacc ttgatttctt ttattaattt gttatttgca
    27721 gtttcataaa cttttactga attttcttgt gtatctgata caaatagtaa cttttcatct
    27781 ttagatattt ctaatccttg gggaatccca tttatttcaa tatttccaat gtatctactc
    27841 gttgtataat ctaaaattct tacattatta taacccaaat cagcaacata aacttttttg
    27901 ccactataat taaatcttat ttctactggt aataaaaatt catataatac cttttttata
    27961 tccatgctta cttcatctat tattataagc tttccatcaa gtgttgatat atacatttct
    28021 ttcttttgtt tatcaagttc tatatgccaa gctctaaagt ccatatttat tttcttttgt
    28081 atatttttat taattgtatc tatacatact atcgagttta tacacggtac atataacttt
    28141 ttgctttctc tatcaaagtc aaatccatgt ggcatattat caactccaat aattcctatt
    28201 ggatttaatg tgtttttatc tagtacatat atactattag aatcttcatt tgccacaaac
    28261 aattcattat cgctaagtac aacttgacta agacttcctc ctatagagac agtatcaatt
    28321 attttatcat tacttaaatc taagacatag agtatcccat tacttgaact aggtatgtat
    28381 attaaatttt tttctttttc tatgcaaaaa tggtgtggat atatattatc ttctaatact
    28441 atttcttttt ctagttcaag tgtagaataa tcaactatgc taatactctt tgataagtag
    28501 ttagaaatat agattttcat ataacccctc ctctctacaa tacatatact acaataatat
    28561 attatttcat tagcttgtat tatgctttat agttgcatta ttacgcatat atttggtatt
    28621 attattaatg ttaaaaaaag aaataatatt taatggaggt ctttttaatg aaagtaacat
    28681 ttaatccaag tggtgtatgt tgtagagaaa tgatttttga agttgatgaa aataatgtga
    28741 ttgttgatgc tgagtttata ggaggatgta atggtaattt atcaggactt agaagcttaa
    28801 taattggcca aaatgctctt gaagttgctg ataaattaaa tggtattgac tgtggtggaa
    28861 aaggtacttc ttgcccagac caattatcta aagctatacg tcaatctata taattactta
    28921 tataaacatc agtaaaatta ttaaaaactt attttatata aaaagagttg tccatttttt
    28981 agacaactct tttttatatt tttatttgta tatttatttt ataaaattat aatttcttta
    29041 ctaaagttct cactgtacca atcatatata atgaacctgc acttattata atatcatcct
    29101 cacttgatgt ttctaatgta taatttactg catcctctat ctcatgcttt gatgttacat
    29161 catctacata ttttaatact ttttctctta atatatctga atttatggcc cttgggttat
    29221 ttggtgttgt tgttattacc ttattaaaat gtggcaacaa tatctctaaa acactatcaa
    29281 tatctttatc ttctaacata cctattaata aggttaattt tctaccttta aaattcttat
    29341 caagtgcttt tgccaaagat tttgctccat cttcattatg tgcaccatct attataaaaa
    29401 ttggattttc ctttatcttt tctattcttc ctggccattt agtatttata agtccttttc
    29461 ttatagattc ttcatttata tttgctaatt tatttatgtc ttttagatat tttattacac
    29521 taattgccaa gatagaattg tttatttgat gttcgcctat caattttatt tcaaggtctc
    29581 tataagtttc tttcattaca gtacaatcgt atatttgaga atttatatct gattttttta
    29641 tgtttatatc atcaaaatca acttctatat atttagcttt tttctcttta caaactgact
    29701 ttataacatc ctttgcttca tcagtctggt catatactag tactactcca ttttccttta
    29761 ttattccagc cttttcgtac gctatttttt ctattgtatc tccaagtata cctgtatggt
    29821 ccaaacttat agatactatc acacttacaa gtgattttgt tattatattt gtagcatcat
    29881 atctgccacc taaaccaact tctaatgcca caaagtctac cttttgttct gaatagtaat
    29941 aaaatgccat tgcagtaacc acttcaaatt ctgttggata tgcatagcct tcttttacca
    30001 taatctctat tttttctttt attaactcaa ttattctagc aacatcatcc tgtggtatat
    30061 tttgtccatt tactcttata cgctcagtaa aagtttctaa atatggagat gtatataaac
    30121 caactttata tccacactct cttagtatat tagaaacaaa agaacacaca gaaccttttc
    30181 cattagttcc agctacatgt attatattca aagtttcttg tggatttcct aataattcta
    30241 ataactttcc gatattttct aatcctaatc ttataccgaa tttattagtt tgtgatatgt
    30301 actctaatgc ttcttcatat ttcattatct aactccccct gtattggcat tttctcttat
    30361 gctatctaat tatagtatat tttttacttt taatctactg acaaagaata catataattt
    30421 aataccttct acattaaatt tagctacaaa tctttattta taagttttta tatctttcca
    30481 ctaattcagt cagtgtatat attgaaacta agtcatattt tgagatgtcc atataattaa
    30541 actttatgtc aaatctatgc tctagctttt tcaacagatt aaaacaatta tcataaacca
    30601 ggcctatctc cttattaaaa aggctacact taaagagttt ttcattattc tcttcaatat
    30661 ctaagcaatc cctaacaacg tcagcaactt tcataaaaag agcattttct ttgtcataca
    30721 aatccaattt aaagtttaca attctactac actcatcaaa atcacaacta tcccaatgat
    30781 ttctagttgc taatgattca agcttatcat ttaaatcaga tattgttatg cctggttttt
    30841 ctgataatat cttagctatt ttaccagtaa gctttgctga taaataacta ttacattttg
    30901 gtggtaatct ataggaatta tttatatcac aacttatata tgaattgcta tccataacac
    30961 attgaacatc atattttttg ttgtaccaaa atgaatcatc tccatctaaa gtaaatcctc
    31021 ttacacctat aacattgtta aacatagctg gataacttaa gtcaaaatca ttagcgagtg
    31081 aacatactat tatttttcct tttctaaaca attcataaca aacttcaaat aagcccttaa
    31141 cactttctac tcctatgact gataaactta aattaattaa tcttatgtta gtgtctaaaa
    31201 ggtatcttaa tgcttcttca agaactttta tatttgtaat accatctttt ctcaaaattt
    31261 ttattacaaa taactctaca tcttcatact ctttctttat tattgatgca caagcagttc
    31321 catgaccatc ttcatcatca aatttatctg atataaagat ataatcatgc atacattcaa
    31381 aagcaattcc tccaactaaa ttatctttta agtaatcatg ttctttgtct attcctgtat
    31441 ctaatactgc aaccttaact ttattattca tatcacatat attctccatt acaaaagttt
    31501 ttaatatatc tatgttaata gttcatctta aactttgatt taagttgcac aatttatctt
    31561 ttaaatgcta tatttcttgc taaaaacata aaataagtac accatatatt taatttatat
    31621 ttattatatc aattattatc attaaatggt taaatgttaa gataaaattt ttagatttat
    31681 atcacaattt agaattattt gtaaaaaagg agattatctt tttattagac aatccccttg
    31741 tatattttat taatatttat ctatgattaa gcatcaattt tattttatac tttttgattt
    31801 taatactata catctaaatc ttatttaggg ggaacaatta tttatatgat ataaaaatgc
    31861 taatttgaat gaacttgtct tataatcagt tttagaaaat acaccattct acaaagtatg
    31921 aatcaaaagg tgaaaaaata ctaaaaataa taaatcaaca tcaattttaa tcaatatatg
    31981 aaaaacttat accaagtatg cataaaaact aatataaata ttattttaac aactaatact
    32041 tacaccttta tatattatat catatttcaa taaataaatt gcataaaagg aaatcttttc
    32101 atagaattaa actatttatt aattcattac tataggttca ataaactata agatgtcgct
    32161 ttaatattta tattgtactc cattaaatat taatataatt aattaaagta tgcgtagcta
    32221 aatgaaacaa atatctatag agttttataa atagtcatta ttttaaaaag gtaatcatat
    32281 tctaaaaata catataatgc atataaaaat caataatagt atattgataa tcaagctact
    32341 aattaataat catgctacta taatggaacc tctacatata catattaaac catattaaaa
    32401 atctataaac tgctattttg cataataaaa ctgtcttaat ataaataaca ttttatatat
    32461 taagacagtt tcaatcaata gccctgtgat gacattaaat cttttttacg atattttcaa
    32521 ttaccttttt aaaattaata cattatatca cataacaagc ttgttaatgc tacttttaaa
    32581 tctttaagtc tatacttact tataggtata aattgttcat taatagtaat catattatcc
    32641 ctaagatctt ctattcttct taaattaaca ataaaacttg tatgacatct aaaaaagcca
    32701 ttttcacaca gtaatttttc tgcttgtttc atgctcatat tagctttata atctctacct
    32761 attgtatgta cgactaaatc tctctttaca gtttcaacat ataaaataga atctatcagt
    32821 attctattaa atcctttttt actatttaaa actatataac gctccttctt tctttgaagg
    32881 ttatcaatac aaagatttac acccattgca aagttactat actctatagg ctttactaaa
    32941 tatctataag cacgaacctc ataaccttgg ggggcatact ctgaaaaagc cgttgtaaat
    33001 ataatttcta ctttttcatc aaactttctt atttttttag ccacctcaat tccattgata
    33061 tctttcattt ggatatctaa aaatataata tcaatttttt ctgggtattt ggatattaaa
    33121 tcttctccac aggaaaattc cagtatttga taatttagac atctttcaga caaaagtttt
    33181 tctgtaaact cttttagtat gcttctttgt attttttcgt catcacatat aactaccctg
    33241 aacataatat cacctccaaa tctaaaatat catttagttt actttatttc aatttccaaa
    33301 ctgtactcac tagctttcaa atttaaattt ctttataaat ttaaattgtc gattaaacta
    33361 cttatagaaa ttctctttaa tatttaaact taaattacga taaattccta tacttttcta
    33421 gatatattat gtaaaaaaat atagtaaaat aaatataata tgtatttatt accctatatt
    33481 aaacatcata atatatcaaa tttttattgc ttataaattt taagacataa aattcatata
    33541 ttcacaacat aaaataaaaa tataacacat ctgtaaagaa ttataacatc atatttgtat
    33601 atatataaag aaaaacatac aaaaagtata gaatatatac tttttgtatg tttttactaa
    33661 ttcttatatt tattttattt tagattctaa atttgttaat ctttcctcaa cagatttaat
    33721 catctcttca aatttttctt tttttgcttt ttcttcttca attaaacttt caggagcttt
    33781 tgctaagaaa ccttgatttg caagctttcc attaactctc tttatttcgc cttctaactt
    33841 tttcttttct ttagataatc tctcaatttc tttttcaaaa tcaactaatt cattaagagg
    33901 tataaatatt tcaacaccat caataactac tccaactgca tcttctggaa cattagattt
    33961 atcttttgct atctctacat ttgaagcaga tgctaaagtt ataaaatagt ctttaccaag
    34021 ctcaatagct tctatttttt cttcacttgg gattattatc aatttagctt tcttagaagg
    34081 tggtacattc atttctgctc tcacatttct tatacttctt ataccttcca tcaataagtt
    34141 catcatatct tcttcttcag ccatgttatc ttcttcatta tattttggcc attcagatac
    34201 tattatacat ccttcaacag taggaagatg agtatatatt tcctctgtta taaatggcat
    34261 gtatggatgt aataatttta atattttttc aagaacataa gttaatgtat ataatgctgc
    34321 agatttagca tttgcatctt ccccatataa tctaggttta accatttcaa tataccagtc
    34381 acagtattct gaccaagtaa aatcgtatat cttttgaagt gctattccta aatcaaactt
    34441 atccatgtta ttagttgctt cttttacaat attatttgct cttgatatta tccatttatc
    34501 agctagagtt aaatcctctt taacactttc tctagtcatg tttttaatta tatcttcatc
    34561 aatattcata aatacaaatc ttgatgcatt ccacaactta tttgcaaagt ttctagcaaa
    34621 ttctactctt tccatataga atctcatatc atttcctggg gaatttccag ttgttaatgt
    34681 aaatcttagg gcatcagctc catattgctc gattatctcc aatgggtcta taccatttcc
    34741 taaagattta ctcatttttc taccttgaga atctcttact aatccatgaa ccaaaacatg
    34801 gtcaaatggc ttttcattca tacagaacat acctgcaaat gccattctaa ctacccagaa
    34861 gaatattata tcgtatcctg taacaagtac acttgttgga taataataat ctaaagcttc
    34921 agtcttattt ggccatccta gagtagagaa aggccataat gcagaactga accaagtatc
    34981 taaggcatct tcatcttgtt taaaatgagt gcttccacat ttaggacact tctctggcat
    35041 ttttctagca actactattt ctccacactc ttgacaataa taagctggta tttgatgacc
    35101 ccaccataat tgtcttgata tacaccaatc tcttatattt tctagccatt gtaaataagt
    35161 tttatcaaat ttatctggaa caaattctaa ttctcctttt ttaagaatat ctatagctgg
    35221 ttttgcaagt tcttccatct taacaaacca ttgctctgat aatctaggct caactactgt
    35281 atggcatcta taacaagttc ctacattatg attatgctct tttatcttaa ttaggtaacc
    35341 ttgttctttt aagtctgcta cgatagcttt tctacactca aatctatcca taccttcata
    35401 ttttccacaa acttcattca tagttccatc ttcattcata gtatttaatt gctcaagatt
    35461 atgtcttaat cctacttcaa aatcattagg gtcatgtgct ggagtcatct taactgcacc
    35521 agttccaaac tctaaatcaa cataactatc tgcaactatt ggaagttctc ttcctactaa
    35581 tggaagtatt gctgtttttc ctattaaatg tttatatcta tcatcttctg gatttactgc
    35641 tataccagta tctcctatca ttgtctcagg tctagttgta gctatttcta aaaagtcttc
    35701 actatctttt agtgggtact ttatatgata aaagtttccg tcgtgttctt catgttcaac
    35761 ttctgcatct gataaagtag ttttgcaatc tgggcaccag tttattattc tatttcctct
    35821 gtatatgtga cctttttcat ataggcttac aaaaaattct ataactgctt cattacaccc
    35881 ttcatccata gtaaatcttt ctttatccca atcacaagaa tcacctagtt gtttaagctg
    35941 attagatatt tttcctccaa attcatcttt ccattcccag gctctcttta aaaattcttc
    36001 tctacctatt tcatactttg tcttgccttc ttgttttttt attctttcaa caactttaac
    36061 ttctgttgct atagaagcat ggtcagttcc tggaagccaa aaagcttcat atccatccat
    36121 acgtttccat ctgattaata tatcttgaag tgtatggtca agagcgtgtc ccatatgcaa
    36181 ttgccctgtt atatttggtg gtggcatcat tattgtaaat ggttttttat ctggatttgg
    36241 tttagattta aaataccctt catccatcca ttttttatat agcctagcct caaaatcttt
    36301 tgggttataa gtttttgata aattcgtatt ttccattgtc ctgcctcctg tattttataa
    36361 ataaattttt taaatatctt tagaaataaa aaagagctct tcatcctctt taaaaaggac
    36421 gaaaagctcg cgttaccacc ttaattccaa agcttaaaat acattaacat ataattaaat
    36481 tattggttaa tgttatttta tcaactttga ctctcaaaga atttaacggt tctaaccgtc
    36541 taaacttact tatagttcag tttagaaact ccaaagctac attcagtaaa tcttatactt
    36601 agaaaatctt acagccagtg aattttcctc tcttttagta gtatttactt actcctcttc
    36661 ttctcagtct ttaatattac atattattat atacaaatat tattctcttt gtcaattatt
    36721 tttattttat tttttctgaa ttttcttaat tatgtttatt ctcttttata tagttgttat
    36781 attttaaaat atgtttttac agttattttg tcttataatg tcaataattg caagattatt
    36841 ttattttaat gctttctcat taattttata ttatattatc cttacagtat acctcttatt
    36901 cgtatttttt atattatatg ttttatttta taaataattt actttatctt ttactatatt
    36961 taaatttatt ataagttttc ttgccagaaa tttttaggtg ttatattttc tgtaattggc
    37021 aatattgtat atcctctctc ttttaagatt cttataatat tatttaaagc atttaaactt
    37081 tgctctttct catgaattaa tactactaat tcatctcttt ttcttccata atataatata
    37141 ttacttacta tctgacttgt agaagacttc caatcctgtg tatccaaatt ccagtcccaa
    37201 attaaataat catttgccat aagtttatta tatgaacctt ctggcatata tggtttactt
    37261 ccgtatggta atcttattaa ttttgaactc tgaccagtta tttcttgtag agtattattg
    37321 catgtattaa attccccaac tgttacttct gggcttttat ataacttatg tatatcatga
    37381 cttacactat gaaaacctat tgagttttct tcttccaaga ctctccttac ttcttccttg
    37441 tggtttttca tattctgatt aagcatgaaa aatgtcgctt tgacatcatt ttcttttaaa
    37501 atatcaagta gtgcatttgt atattttgat ggaccatcat ctattgttat gtatgctact
    37561 ttttcagaag tagcccctgg accttttgtt tcttcttgag atgctttgta tatgatttct
    37621 cctaaagtat tgctttgaga aagcagttcc agtgtatttt caccttttga acttatattt
    37681 tcaactggaa cattattaat tttttcctcc aataatgttc cagttaaaat taaaacagct
    37741 ataataaata tccttataaa tacatgaaaa acagccttat tatctttaat tttcatcccc
    37801 catatctccc ttttataaaa gcataagttt aagacttaaa aagttatttt ttatatttat
    37861 tctctttctt attacttttt atatctctac taaatatttt tttaaccttt tcttcttctt
    37921 tttctcctaa agattctact cttttgattc ccaaagaagt taaaaattgt aatacattta
    37981 aattatcaaa tggagtttcc atattcgtac tttcactata ttcatcaaca ttcttagtac
    38041 cttcttccac acttaaaata cgcttcggac ctcctacaca gcctcctaca caccccattc
    38101 cttctataaa tgtagcttct atttctttat ttagaacttt ctttagaccg tccatgcact
    38161 cttttgttcc ttcaaatgcc ttttcttcaa attttatatt tttgtcaatt cttctaactg
    38221 ataacttaac tgctttactt acacctcctg ttctagcata aactctacct gaaagggacg
    38281 cctctactct attactctca tccattattg ctggatttaa ctctaatgca tcaaatattt
    38341 cttgcaactc tttaaatgta agcacaaaat caactgcatc ttttatatct tctaacattg
    38401 cttctttctt ttttgccata caaggaccta tgaatacaac tttagcatct ggatttaaaa
    38461 tttttacagc tctcccacaa gcaatcatag gagaaacgga tggtgataca ttttccaata
    38521 tttgaggaaa actattttgt atcaaactaa cccaaatagg acagcaacaa ctagttataa
    38581 agcatccttc ttcgtccttt ttcatatgct cataataatc atatgcttct tttgcagtaa
    38641 gcatatctgc tgccaaagca acttctatca tatcttcaaa tcctatcttt tttaatgcag
    38701 ttcttaattt accagggctt acatctttcc caaactgtcc tacaaaagct ggtgcaacta
    38761 ttgcatatac agggctcttt atatctttta acaattttat cattggtata aattctattt
    38821 tatctgaaat tgcacccaac ttacatcttg atacacaatc accacaagca ctacatacat
    38881 cttcctcatt acaattaata tgcttacttc ttatcttaca tgactcatct tccttattat
    38941 tttcatcaca atatttgcaa gcatctgata ttacagatat tattggtctt ttgacttcat
    39001 ctaaatttac agcttcatgt agtgactctt ttaaattttt atctgtatct tctgtcacat
    39061 ccaatcccat agttacccta attaaattta ccatagtatc tttatcaaat tttccactaa
    39121 aataattatt taaattatcc tttaaatttt catttaaaat tttattaggt aagttttcaa
    39181 tatcctctat gtcatcattc cacactgctt ttacaagttc gccaaaaagc ttcattttat
    39241 atatttctag tattttagaa ttgtcatttc tagtattcat aaaaaatagt acctccataa
    39301 attaaactta tatatgttta atatttacaa agatactatt ttttatttat tatttaacta
    39361 ctattattaa tatgatttat ttagttttct caacaactct atttcaatca ttattttcat
    39421 tagatgatag ttgaatacag ggcttttttc ttcatctata ttccagtcta gcttatccac
    39481 attatatgtt ttcttaaggt atttatatgt atgctctttc aaataaagtt tattttcaag
    39541 taactctata gactgcatat gaaaatgtat ttctctacat atccttaagg cattctcaat
    39601 tttttctata ttagtttcac tcaaactata atccaactca tcaataagct ttgaatatat
    39661 ttcttctaat ttttctactt cttcttcaaa tttctctaca tttaaatttt cttttctaat
    39721 aattttatct tcaataagca acattgaaag ttcttctatc tttttaaact catctataac
    39781 actatttaga taatttggtc tagcaacata ataattaaca agtactccaa acaaaacacc
    39841 cacagatgta tctaacaccc tatgtaaaga ataatacaca gggtcactat ttcctacacc
    39901 tagatgtata gccagaaagg ttacacaggc aactactact gactttattt taaacagatt
    39961 gcataaatat attgagcaca ttactcctag accacataaa aatgggtctc cagctttaat
    40021 gatggcaaat atgaatccta ttataccacc taaaatagta ccttccactc tattgattcc
    40081 cgtctttaaa gaacctttta ctgtatcttg aacagaaatt atacatgcta ccagagaata
    40141 aaacatattc tctactaaat agtcaccaag aatcatacat aaagtgacac taattcctgt
    40201 ttttatagtc ctcataccca tcttttgaag tttcaaagtt ccacctccta aaaagcacct
    40261 tatataaaat acgcatcctc atatttaata tgttcctagt atatcacaat tttttaaatt
    40321 tacccattaa tcatattttt ttatcaattc tttcttaatt tagacaataa aaaaactgct
    40381 ttaaagcagt tttttatcct atctcaacca ttttaccctc aattgcaaaa attatcttct
    40441 cacatacatt tgttatatgg tctccaattc tttcaaggta tcttcctata agtagaagtt
    40501 ttaccccttg gtctatggta tttgagtttt catgcattat ttttaaacaa tcaatttgta
    40561 cttgttcata caacccatct acaatatcat ctttagttcc aacatcataa gctatacttg
    40621 catcaaataa gattaaagct tctctagtct gagacatcat agacttacat tcttttgcca
    40681 tcttaggaat atctattagc tcttttatat aagcctctcc acctatcttc aacatttctc
    40741 tagctatatt tgctgcataa tctcctattc tttccagctc tatagatata ttacctaatg
    40801 aataaataaa tcttaagtcc cttgccattg gttgctttaa tactattagc tctatactct
    40861 tatctcttat ttcttctctt aatttattta tttcttcatc atcttctact acttttcttg
    40921 caccctctaa atccttctct atcatacaag tcacagactt ttctattgct tcttcacatt
    40981 tttccatcat aagcactgtt tgttctttta aagtatcaat acttatatct aaactattat
    41041 tgaccattgt ctaactcctt tatagttata tattttaacc aaatctacct gttatatagt
    41101 cttctgttct tttatctaca ggagtggtaa acatagtttt tgtatcgcta aattctataa
    41161 cctctccatt taagaaaaaa gctgtttcat ctgatatacg agcagcttgt tgcatattat
    41221 gtgtaactat gactattgtg tagtcttttt ttaaatcctc tataagttcc tctactttta
    41281 atgttgaaat tgggtctaaa gcagatgtag gttcatccat aagaataact tctggtctca
    41341 tagcaattgc tcttgctata catatacgct gttgttgacc accagaaagt cctagtgcag
    41401 atgatttaag cctgtcttta acctcatccc aaatagctgc accttttaag ctttcttcta
    41461 caattttatc taattgcttc ttatctctta gtccatgtgt acgaggacca tatgccacat
    41521 tatcatatat actcatagga aatggatttg gcttttgaaa taccattcct actttagtac
    41581 gaagatttat aacatcatct gaggtatata tgtcctctcc atcaacagaa atgtttcctt
    41641 taattgttac atcttcgatt aagtcattca ttctatttaa cgttcttata aaagttgatt
    41701 ttccgcatcc agatggacct attaaagcag taaccttatt ctcttttata tccatattta
    41761 ttttctttaa tgcttgctta tcaccataaa ataaatccaa atcttttaca ctcattttta
    41821 tcttatcgat taattccatt attcacacct cttaaattta ataattagct ttatttaatt
    41881 tcttagcaac aaatcttgct agcatgttta gtgctaatac aattactatt aaaacaattc
    41941 ctatactggc tgctgttgct atatctccac tctctttagt cagtaagtat gagtgtacag
    42001 ttaatgttct tgcactatca aatattccac ctggcatctt ggctacagta cctgctgtaa
    42061 gtaatattgc agctgattct ccaattatac gaccaactga taagattact ccagataaaa
    42121 ttcctggtat tgcacttgga agtactacct tatataaagt ttgaaatttt gtagctccta
    42181 atgccaatga tgattctcta taagcttgag gaactgtttt taaagcttct tctgttgtac
    42241 gaattattac tggtaatatt attattgcaa ctgtaagtga acctgcaact atggaatatc
    42301 ccatttttaa tgtaactaca aagaaaattc ctccaaataa tccatatact atagatggta
    42361 tccctgataa actttcagtt gcaaatctta tagctgtaac tgcttttcct tttttagcat
    42421 attcttgtaa atatatagca gccaatattc ctataggagt tgctacaact atagaaacta
    42481 ctactgtata taatgttgta attatcattg gaagtatacc accatcacct gatgctgaat
    42541 aattgctaaa taagaaatta aaattcatgt tgccaattcc ctttataaat ataaatccca
    42601 ctataactac taatgatact attgtaaata gtgctgatag atatactaat gacttcaata
    42661 gattctcttt gaactttctc atcttaattt accgccttat ttgaaagttt atttaaaact
    42721 aagtttaaaa ttaatataaa tgtaaacaat actactccag ttgcaaatag catttcttga
    42781 tgtgtaccaa atgcgtatcc catttcaagt gctatattag ttgtaagtgg tcttacacta
    42841 tctgttattg cagttggcat aactggtgag ttgcctgcaa caagtattac tgccattgtt
    42901 tcacctaaag ctcttcctac tcctaacact actgcggcta atactccaga ttttgcagca
    42961 ggtaatacaa ctttgaatat tgtttctatt tttgatgcac caagtgctaa tgaaccttct
    43021 ttgtatgctt ttggtactgc tcttattgct gtttctgata cagatattat tgttggtaac
    43081 atcattactg ctaatactat tactattgct aacaaacttt gaccttttgg aagattaaat
    43141 atactttgta tagttggaac tatcactgca agaccaaata caccatataa tactgaaggt
    43201 atacctgcta aaagttcaac tgctggtgac attatttttg ctaatctttt aggtgctact
    43261 tctgctataa atacagaggt taatatacca acaggtactc ctataacaag tgctccaagt
    43321 gttgcaaata ttgatgctac tatcatagat gatattccaa atttattggc agaaggaacc
    43381 caatctgcac cagttaaaaa gtctataaat gaatatcctt caaatataaa tggtcttaat
    43441 cctttataaa atacgaatcc tattatcaaa agtaaacttg caactgctac taaagcacta
    43501 agtagaaaaa tattttttgc tactttttca attgcgtatt ttgtcttatt gccattattg
    43561 tcattttttt ctaaacctac taatctagat tttactatca taataccctc ccattaaaat
    43621 atacttatcg attttcgttc tgtattcaaa atttaatttt ttataattcg tcttcatcaa
    43681 atttcctata cttttattct acttttttta agttaaatct atattaggat taagttaagc
    43741 aagtgtaaaa ttatatttac tttttaacat taattttact tttaaaacta tatttgacat
    43801 ttactttaca atatactgtt gtttctctat attaaaatag cagatataga taataataca
    43861 gtttatgtat aatttattac ctatatctgc tattaagatt tgttaactaa atttaacttt
    43921 tatactacat atataattat tgtatcctct agtttatatc actattattt ccatcaaatt
    43981 gttacgatac ttgatgtttg caataggtac gaatagccaa aaatataaaa ataggtattt
    44041 ctatcactga gaaaaacagt ataatgtgtg gtgtccaaaa actcatacct cctaagtgta
    44101 agaaattaaa tgatgtcatt tgatataata aactaatctt aaaaccaatt ccccctggtg
    44161 gtaataggta tccaatccaa ctaacaccta ttcccatagg aattaagcaa atagaaaaag
    44221 caatcagcat agaagtaaga gaatccttac attttgcaga taaaaataat gttaaactaa
    44281 ccattgcaag tattgaaatt agaccaccaa tagctataag aatctgtgct tgtagtaaat
    44341 ttatatttac tagactaatg acagaaaaca acatttgaaa tgaggttttc aaacattcag
    44401 taccaaaagc taaatcagaa attgccaaat ggatagaaat acatataaca aacattatta
    44461 taaatataga aaatagagct aatattttag taaacgctag acgaatatgt ccatgtttcg
    44521 tacaacgaag gatgctatct gattgtgtct gatactcacc agaaaaagta ggtgcagcaa
    44581 ttgcaacata tataattaat aatataaaaa tataaaatat tatataatcg aaagcatctt
    44641 ctggatttat taagaaattc ttaatcttat tatttaa
//
LOCUS       DAEPUT010000028        44014 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.028, whole genome shotgun sequence.
ACCESSION   DAEPUT010000028 DAEPUT010000000
VERSION     DAEPUT010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44014
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.028"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            139..393
                     /locus_tag="KRL22_001653"
     CDS             139..393
                     /locus_tag="KRL22_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272150.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            438..761
                     /locus_tag="KRL22_001654"
     CDS             438..761
                     /locus_tag="KRL22_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272151.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(1320..1514)
                     /locus_tag="KRL22_001655"
     CDS             complement(1320..1514)
                     /locus_tag="KRL22_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1272152.1"
                     /translation="MINYMVEIIYSEKISEIENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(1887..3506)
                     /locus_tag="KRL22_001656"
     CDS             complement(1887..3506)
                     /locus_tag="KRL22_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH1272153.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            complement(3815..4021)
                     /locus_tag="KRL22_001657"
     CDS             complement(3815..4021)
                     /locus_tag="KRL22_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1272154.1"
                     /translation="MFKKKSGYTFTNFLSKVRVEKSKKYILKKDLSTLDVAVLIGLNS
                     QNYYSIIFKKFNNFTPIEYKNIYN"
     gene            4313..4504
                     /locus_tag="KRL22_001658"
     CDS             4313..4504
                     /locus_tag="KRL22_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272155.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(4593..5405)
                     /locus_tag="KRL22_001659"
     CDS             complement(4593..5405)
                     /locus_tag="KRL22_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HBH1272156.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            5826..6977
                     /locus_tag="KRL22_001660"
     CDS             5826..6977
                     /locus_tag="KRL22_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1272157.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            7095..7733
                     /locus_tag="KRL22_001661"
     CDS             7095..7733
                     /locus_tag="KRL22_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH1272158.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            7734..8756
                     /locus_tag="KRL22_001662"
     CDS             7734..8756
                     /locus_tag="KRL22_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HBH1272159.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            8746..9366
                     /locus_tag="KRL22_001663"
     CDS             8746..9366
                     /locus_tag="KRL22_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272160.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDFKMNDYMENCNM
                     MAGLALDKIGIVCLDYINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(9493..10179)
                     /locus_tag="KRL22_001664"
     CDS             complement(9493..10179)
                     /locus_tag="KRL22_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBH1272161.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMIGDSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(10193..10738)
                     /locus_tag="KRL22_001665"
     CDS             complement(10193..10738)
                     /locus_tag="KRL22_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1272162.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            10966..12213
                     /locus_tag="KRL22_001666"
     CDS             10966..12213
                     /locus_tag="KRL22_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1272163.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSSGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            12300..14294
                     /locus_tag="KRL22_001667"
     CDS             12300..14294
                     /locus_tag="KRL22_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH1272164.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDVVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIKNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDVLKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            14294..15616
                     /locus_tag="KRL22_001668"
     CDS             14294..15616
                     /locus_tag="KRL22_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH1272165.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRS
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            15895..17181
                     /locus_tag="KRL22_001669"
     CDS             15895..17181
                     /locus_tag="KRL22_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH1272166.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            17267..18573
                     /gene="grdB"
                     /locus_tag="KRL22_001670"
                     /pseudo
     CDS             17267..18573
                     /gene="grdB"
                     /locus_tag="KRL22_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
     gene            18850..19581
                     /locus_tag="KRL22_001671"
     CDS             18850..19581
                     /locus_tag="KRL22_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1272167.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            19583..20941
                     /locus_tag="KRL22_001672"
     CDS             19583..20941
                     /locus_tag="KRL22_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1272168.1"
                     /translation="MINLFSSDLFLKYSFFFSFIVYRILMVIVQYYFLINFTNFNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSNYFQINVLLVISLHCA
                     SI"
     gene            20980..21465
                     /locus_tag="KRL22_001673"
     CDS             20980..21465
                     /locus_tag="KRL22_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272169.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKALQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKGKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(21728..21964)
                     /locus_tag="KRL22_001674"
     CDS             complement(21728..21964)
                     /locus_tag="KRL22_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272170.1"
                     /translation="MLLTHIYFNGQFKQTIELYKQAFNATVKTLIEDSCYLLIVHNEI
                     VIHNKFLILNDFGNKNGVSISEGYQPTDKIQTAS"
     gene            complement(22119..22343)
                     /locus_tag="KRL22_001675"
     CDS             complement(22119..22343)
                     /locus_tag="KRL22_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1272171.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(22440..23693)
                     /locus_tag="KRL22_001676"
     CDS             complement(22440..23693)
                     /locus_tag="KRL22_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HBH1272172.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNDFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            23967..24956
                     /locus_tag="KRL22_001677"
     CDS             23967..24956
                     /locus_tag="KRL22_001677"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBH1272173.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHEKAYNLVKDKKILLELCPTSNVQTKTVDSYEVHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            25028..25768
                     /locus_tag="KRL22_001678"
     CDS             25028..25768
                     /locus_tag="KRL22_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HBH1272174.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            25984..27135
                     /locus_tag="KRL22_001679"
     CDS             25984..27135
                     /locus_tag="KRL22_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH1272175.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            27160..27915
                     /locus_tag="KRL22_001680"
     CDS             27160..27915
                     /locus_tag="KRL22_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HBH1272176.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNNNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            28107..30494
                     /locus_tag="KRL22_001681"
     CDS             28107..30494
                     /locus_tag="KRL22_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HBH1272177.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(30725..30958)
                     /locus_tag="KRL22_001682"
     CDS             complement(30725..30958)
                     /locus_tag="KRL22_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBH1272178.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            31247..31837
                     /locus_tag="KRL22_001683"
     CDS             31247..31837
                     /locus_tag="KRL22_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1272179.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            31951..32796
                     /locus_tag="KRL22_001684"
     CDS             31951..32796
                     /locus_tag="KRL22_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272180.1"
                     /translation="MIKVDDLSFSYTERDFLQNINFGVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            32793..33476
                     /locus_tag="KRL22_001685"
     CDS             32793..33476
                     /locus_tag="KRL22_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272181.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            33473..34189
                     /locus_tag="KRL22_001686"
     CDS             33473..34189
                     /locus_tag="KRL22_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272182.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISFLLNLSISLLVLLQGIIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            34286..34549
                     /locus_tag="KRL22_001687"
     CDS             34286..34549
                     /locus_tag="KRL22_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272183.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            34521..34976
                     /gene="def"
                     /locus_tag="KRL22_001688"
     CDS             34521..34976
                     /gene="def"
                     /locus_tag="KRL22_001688"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH1272184.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEEEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            35028..35489
                     /locus_tag="KRL22_001689"
     CDS             35028..35489
                     /locus_tag="KRL22_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HBH1272185.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIIF"
     gene            35539..36441
                     /locus_tag="KRL22_001690"
     CDS             35539..36441
                     /locus_tag="KRL22_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1272186.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GALYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            36811..37623
                     /locus_tag="KRL22_001691"
     CDS             36811..37623
                     /locus_tag="KRL22_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1272187.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYNVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINKDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNIKGEAYSDDSMTMGLVLQK"
     gene            38671..39432
                     /locus_tag="KRL22_001692"
     CDS             38671..39432
                     /locus_tag="KRL22_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH1272188.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLARILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEKCIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            39497..40279
                     /locus_tag="KRL22_001693"
     CDS             39497..40279
                     /locus_tag="KRL22_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH1272189.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKGKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKKIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            40546..40965
                     /locus_tag="KRL22_001694"
     CDS             40546..40965
                     /locus_tag="KRL22_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HBH1272190.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(41068..41334)
                     /locus_tag="KRL22_001695"
     CDS             complement(41068..41334)
                     /locus_tag="KRL22_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBH1272191.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            41561..42262
                     /locus_tag="KRL22_001696"
     CDS             41561..42262
                     /locus_tag="KRL22_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272192.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            42344..42952
                     /locus_tag="KRL22_001697"
     CDS             42344..42952
                     /locus_tag="KRL22_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1272193.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            43276..43740
                     /locus_tag="KRL22_001698"
     CDS             43276..43740
                     /locus_tag="KRL22_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HBH1272194.1"
                     /translation="MKKLVIILISIISVVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNIWH
                     GSVDNDTFAISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
BASE COUNT        17555 a         4558 c         7089 g        14812 t
ORIGIN      
        1 ttaaaaaatt taaatatata aaactataaa ggttacaatt ttggaaatag atgtaaatat
       61 atgttgtatt gtataataag agtaatataa aatctagtaa aaataatcaa ataaatttag
      121 cttatgagag ggataactat ggaaaataag gattttaaat taacaatatg tatatttgct
      181 tttgtaattg gagtagtagt attattctgt tgtataggtt taggtgaatt tagtgcagag
      241 catattattc aacaaaatgg tggaatcatg gatactgacc aatataatat ttatctagac
      301 caatctattt ctcaatatag aaattttggt tctatattgg ctctgttagg aggaataggg
      361 atattgtttg ataaatatat cagaaaatac tagagattat gttttgtcta aaataaattc
      421 ttatgaggag ataaaaaatg gcaacagaaa tatttactgt aaaaattaca cccttagagg
      481 cacaaaaaat gataaaagaa aatcttgatg cagatttagt ttttagtgat tcttataatt
      541 taggagatga taaatttata ctaattacaa cttttgagaa gtattacgca agaaataata
      601 gtgatgcagg attaatagta gtttatgaaa ataccacagg aaaaacagtt attaaagcta
      661 cttcaacagg cagtgcaatt ggaattttaa aaattgattg gggtgcaggt ggaaatttac
      721 ttaaaagagt aaaaaacata cttgctgatt atattattta attattttat ctaactgata
      781 atatgtcaag aaaatctcgt aaaagaggtt aagaacattt ttataatata tagataaata
      841 agaatttgaa ggtaaagttt ttaaggtata aagaaaaata atataataaa acgaattggc
      901 tttataattc tttataaggc aaagagcaca tttctttata taattgttgg atattaaata
      961 atatgtaaat acaccattta catataaaag tttaattaat atgttaagag aaaatgaaat
     1021 ggaaattact aaaaaatatt tttaaattgg ataatggttg atattatgtt tatacaaaaa
     1081 tcatgtagaa ttttatatat tttaaatatg atagtttaaa attatgaaag aatgataaat
     1141 tccagtttgt agggtaattt tgataaataa tattaataag tatgagtaaa aagtaggagc
     1201 atattaatat aatgtcccta cttttttatt attaaaattg tttataatat caacactaca
     1261 ttaaaacaca acctaaattt gaaaaacaaa tagtttagaa atatgtactt ttttatctat
     1321 tatattcttt taaatcgaat tttttcatct gaacataaag tctcaaatct atatgcgtct
     1381 gtcatatcat aaaaaccaaa aaatataaag ccatcacgag aagtaaattc atattgtata
     1441 ttttcaattt tcaacatgtt ttctatttcg cttatttttt cgctatatat aatttctacc
     1501 atataattta tcattgtaga atccctccta ttaatatgaa aatatccaaa tatataataa
     1561 catatttaga tgatataata gtatccaaat aaaaaataat cttattacat tattgaatga
     1621 agaattaaaa tgaagataaa taaaacaaat attggttata attgattaaa aaatagttat
     1681 gtatacttgt gactttattt atgggcagtt caagttttat gaaagaagtc atatatatat
     1741 ggaatattct aggcagaaac tgtttaatat aagagaatac tataaaaatt tgagtattac
     1801 ataaaaaata agaagccata aatgatataa gcattatcta tagcttctta cttctcattg
     1861 attaagatta tatataaaaa taatcactat attttttgtt taagttttag tacttgtttt
     1921 actatatttg ttgagtggtc agaaattctt tctagattag taagtaaatc aagataaagt
     1981 acaccagcat caattgtaca acttccatta tttagtctaa tcatatgtga atttctaaaa
     2041 gttttttcta aataatttac ttcattttca acttctaaaa ctttatttgc taactcaaaa
     2101 tctttaacat ctaaaactat taaggcatcc ttaaaattag taattgtctt attgtatatt
     2161 tcgtatattt ctcttatcgc actatcagaa aaactaatgt tcatttcctt aacactcatg
     2221 gccaattcag ctatattttc tgcatggtca gagactcttt caatgtcatt tacagtatta
     2281 aaaagcaaat ctgttctaaa gcgttcatca tctctaagag gttctttaga aagttttaac
     2341 aaatagttca atatatcttt ctgtaactta ttgacaactt tttctgactc aaaagcttta
     2401 ttaatatctt cattgctctt atttaaaaat cctgcaattg aatgttccaa agagtttgta
     2461 gctttatgac ccattcttac aacttcttgt acagtattac caagtgctat agatggagtg
     2521 ctaaacatcc tttcatctaa gtacttagta ttatttacta tttctgattc agtttcttta
     2581 ataggtataa gtctatttgc taatttaact atgtatttag aaaatggtaa taatattata
     2641 acatttgtaa gattaaataa agtatgtgca tttgctattt gtctagctgt atcagttggg
     2701 tcaaaatgag taactatggc tgatataggt ttatttaaaa caagcataaa tattattgta
     2761 ccaattacat taaaacttaa atgcattaca gctgcacgtc gagcatttct acttgcacca
     2821 acacttgata aaagtgaagt aacacaagta cctatattat ctccataaag aataggtaaa
     2881 gcagatgata gaggaagtat tccttgagaa gctagtgcta ttaacatacc catagatgca
     2941 cttgaacttt gaacaatacc agttatggca aatcctgcca atatacctaa tacaggattt
     3001 ttactaaaat ataaaagtgc atcagtgaat gctttatatt cagcaagtgg agctactgca
     3061 tctttcataa actccattcc tgtaaataat ataccgaaac ctataagtat ctcagataaa
     3121 tgctttgttt tttgatttga tgtaaataaa tagaataaaa tacctatacc taaagcaatt
     3181 ggtgcaattc cttcaagatt aaatgaaact aattgagcag taactgtagt acctatattt
     3241 gcccccatta ttacaccaat agcttgactt agattcatta tacctgcatt tacaaatcct
     3301 acaaccataa cagtagtagc acttgaactt tgtataatac ctgtaacgac tgtacccacc
     3361 agtacaccca taacaacatt acttgttaag agttcaataa ttttttttaa tttgtctcct
     3421 gctgattttt gtaaaccttc tcccattaaa ctcattccgt aaagaaaaag tccaagtcca
     3481 ccgataaggc taattactat attcacgata tttcctccct taagaaatta ataatttttt
     3541 tatctgaatt ataaacttta ttaactaaaa tttattgttt ccataatata gaataacaaa
     3601 ttttgtcaat aaaaatatta atgttttgtt aagtatacgt taagagaatg ttaaattttt
     3661 aagttgttgt taattttaga aaatttatga tatatagcaa tttaaatact tgaacttaga
     3721 tttttagtat tttatgtaca atcaatttaa caaagaatta actataattg taaaaaatat
     3781 gtaaaaaaat aacatctttt tagaatgata ttttttagtt ataaatattt ttatattcaa
     3841 ttggtgtaaa gttattaaac tttttaaaaa ttatactata gtaattttga ctattgagtc
     3901 caattagtac agcaacgtct aaagtagaca agtctttttt taatatatac tttttgcttt
     3961 tttcaactct aactttactt aaaaaattag taaaagtata tccacttttt ttcttaaaca
     4021 aagaaaaaaa caacttttat taagttgtaa ttcattacat atattactta ctgttatatc
     4081 ttctgagtaa tttttgtgaa tataatctat agttttcttt acataaaact aagagttggt
     4141 ctatgtttca ttttatcaag gcatatttat taaaaaatca atttctattt gttaaaataa
     4201 tttatgaatg atgttagaaa ctgtaatata ttggatataa tataattaag ataaactctg
     4261 tattaagagg atatatagtt tatcttaatt ataggggaag tgaggatata ttatggaaag
     4321 attaatggaa ctcatagaaa gaaaattttt aaaggatgta gaacttttag aattagaaga
     4381 catagaaaat gtaatagaat gcaaaatgac acagccatat aatgctcatt ataatgaata
     4441 tttagtaaaa gtaaaaaatg gagatgaagt agaagaatat tttgtgtatt taaaacatag
     4501 ataaacataa aagaggttta tatttatttg tatgattata aaataaatac aagcctcttt
     4561 ttttgataaa tataaaatta taaaattttt atttatttaa ttttttcaac aacattagtc
     4621 aatattgaat ctaaatcatc actaatttct gtaactccat tatgagtaat atctataatt
     4681 tctttagtca taggaagttc tcctaaaagt tctaagtcta aatcatctaa aaacttttca
     4741 gtagattctc cttcaaataa cttgattttt ttagaacaat cagggcattg gatataactc
     4801 atattttcaa taactccaag gacatttatg ttcatttttt tagccatatt aacagctttt
     4861 gatacaatca tagataccaa atcttgaggt actgaaacca taactattcc acttatagga
     4921 atagattgca taactgttaa ggcaacatct ccagtaccag gaggcatatc tattaataaa
     4981 tagtctaatt cttcccaaag tacatcagta taaaattgct ttacaacccc tccaagtaaa
     5041 ggtcctctcc aaacaacagg ttcattttca tcatctatca taaggtttat agacattact
     5101 tttatgttat ttgagttttc tacagggtaa atataagagc catcagaata agcttttaca
     5161 ttttttacac ccataagtct aggaatactt ggtccagtta tatctgagtc taatatacca
     5221 accttatatc ccattttgtt tagcttatta gcaagtaaag cagttacagt tgattttcca
     5281 actccaccct tcccactcat aacaccaatt atttttccaa atttattgtt agggttattt
     5341 tcaatagaac aatttgattg actattacaa tttccctttg atggacatga attacaatct
     5401 gccatatcta ttacctccaa actttaatat ttattagatt atttgtaacc tacatatact
     5461 attttagtac aattgaacca taaagtcatt atttaaaagc aacttagaag attttctatt
     5521 gatttattca tagactatag caaaaagaat acaataaaaa aattataaca ttcttgaaaa
     5581 agtgattatt tcaatttagt tatagaactt agtcatataa atatatagaa aatattttaa
     5641 tatattatac ataacgggtt attttataaa tttaactata aattaggttt atattttata
     5701 aaaatttgct aaaaaaacaa ttaaaaattg taaagaaaaa agatataatt agaactgtag
     5761 taataaatgt tttattatag ataatagagt tttaagtatc ttaaataata tttggaggaa
     5821 tatgaatgga attaagacca agaagtgcaa aattagaaga atttgataaa gtaatagaat
     5881 taataaacta tgtatttaga atatcaagaa atcataaacc aactatgatg gaagaatttc
     5941 ctcttttact aagtaaaaat aatatagaaa atatgattat aatatcagaa gatgataaag
     6001 tggtttctga tgtaaactat ctaattcagg atgtatctat tcaaggaaac agattgaagg
     6061 ttgcagctat aggtggagta tgtactcatc cagattatga aaagagaggc tattcatcta
     6121 agatattgga taaagtagaa gaaaaaatgt tttatgatgg tgtagatatt gtaattatat
     6181 caggaacaag aagtctatac agtagaagaa attgtagttt ggtaaagagt ttttataaat
     6241 atacaataaa acctgaagat gtaaaaatag catatgaaat agttgaattt gatgaaacta
     6301 attttgaaaa agataatgat ttagataaaa tgattgaact atataatcaa aatagtacta
     6361 gatttataag aacgagagat gagtttcaaa aactattgca tgcagcaact attgcctggg
     6421 gaccaattgg ttacaagaag gtatttataa aggaaaataa taatataata ggatatttga
     6481 taataagaac aataaaaaaa gaagattcta ctgtaggaga agttgctgaa atagggttaa
     6541 actctgtaaa tgttgaaaat atattgaaat atgttgcaaa taaatttgga ttagaatatt
     6601 taaattataa agtacatgtg aaaaatctta aagaccagtt gaaatgtaat gggacaaaat
     6661 ctttggacta tcaacaagga actatgaaaa taataaattt tactaagttg tgtgatagtt
     6721 taagaagtta ttttagtcaa tatgtagatt ttgaattact aaaatacatg gaatttaaac
     6781 aagttgaaaa taaatatatt attaaataca aagaagaaga acttgtaata gaaaatttgg
     6841 ataagcttaa taaactgttt tttgaaaaaa atgaggaaca gtacaatgaa tttaaacatc
     6901 taaaaaatat atatgaattt gctacaaagg catttcctgt agattttcca tggactgcaa
     6961 atttaaatta tcaatagttt tagatgatat taaataaaat tgattgatac ctagagttag
     7021 tccttgttaa ataagagaaa ttattggata ttgaaaaagc aattttgtaa gtaattagaa
     7081 aggatgagta ttatatggac atacttgatg atatagcaga atgtatatta aatatgggtg
     7141 tagataatat agagaattta gtaaaaattg ctatagataa aaatattgat gtggaagata
     7201 tttatgaata tggtttaaac aaaggtatga taggagcttt agataagttt gagaataagg
     7261 aatactatct ttcagaagtt atagtatgca cagatgcatt aaataaaggt attaatcttt
     7321 tgaagggaac tggaaaagta aagaaaaaat caaagggagt aattctgatg tctgtagtag
     7381 aaggagatac tcatgagata ggaaaaaata ttgtaaaagt aatggtagaa gccactggat
     7441 ataaggttat tgacttaggt gtaaatagaa aaagtgaaga tataatagaa gaagctataa
     7501 aaaacaatgt agatataata ggcttatctt caatgatgac aactacaatg gaaaatatga
     7561 aatcggttat agacgaactt aatatgattg agatagataa aagaccaaaa gtaataattg
     7621 gtggaggtcc tgtaagtatg gagtttgcag aagaaatagg agcagatgga tacagttcaa
     7681 atgctccaaa agcagttaaa ttaataaata aacttatagg aggtgaagtt taaatgtttt
     7741 cagatatgac tttacttcag tatataaata gtgaagatag aggttttttt ctgcctgata
     7801 tgggtacaaa tggattgttc ttaataaata aaaaggcata tgaagtatat gatagtgtag
     7861 atttgcaatt agaattagca aagactatgg acaagtattt tgaatcagat tttatatact
     7921 cattctgtga tgggattaca ttttgtgaaa ctctgggttt agagacatta agaccagatt
     7981 atgattttcc aagtgtattg acacatacta taactgacag agataaatta agaaaattag
     8041 atgttccaga cccttatacg agtggacgta tgccactcaa tatagagagc ttatcagtta
     8101 tatcaaaaag tattaaaaaa ccactatatg aatcgataca aggtccattt acacttgcag
     8161 gtcaattagc tggagctact caacttttaa gatgtataat aactgataaa aaatttgtag
     8221 aagaattatt ggaatttaca actgaattgg taagaagata tgctgtagct gcaaataaag
     8281 caggagcaaa atatatttca atagcagagc caacatcagt aaccctaagt aaagatagat
     8341 ttgatgaatt tatagtaaaa aatttaaata aaatctacaa tgaacttgat tgttggaaag
     8401 gtatgcatat atgtggagac accagagaat tattagataa tatgctaagt tgtaatatag
     8461 atgcagtaag tttagaccaa attttagact atgaagaaat tgctcctatg attcctagag
     8521 atatagtttt gattggtaat ttagacccaa taaaacttct tggacgttct aagccagata
     8581 agattagaag agagacgcta aaattgttaa agaagatgag aagatatgat aactttttat
     8641 gtgattttgg ttgtaactgc ttaaatacca ctccagtaga aaatttacaa gcagctataa
     8701 aggcaggaag aattagttat aaagaattag ataggattga tattgatgaa ttataatagt
     8761 aataaaaata aatatctttt aaaggatata aatttagatg atatttttat agataagaat
     8821 attgtgctaa agtttttggg gtatggaaat agaaaagctc cagatacaat tagtaaaatc
     8881 gttgaaagag aaataagaaa tataaatgat attttagata tcaagatata tataagtgaa
     8941 gttgatatta ataaaacacc taaagaatgt aaaaaagcat ttgctgtact atatacaata
     9001 ggggataaaa ttgattttaa gatgaatgac tatatggaaa attgcaatat gatggcaggg
     9061 ctagcattgg ataaaatagg tatagtatgt ttagattata ttaatgagaa aataaaaatg
     9121 tatttaaaag gaaagtatga tagtctcaaa atatcgcatg aaatatatcc aggagataaa
     9181 gattttgaag tagagagaca aaaggatatt tataactatg taaaaaataa atataatagt
     9241 atagaaatag aaatcaatga ttatcatcaa ctatccccca taaaaagtgt tgcaatgctt
     9301 attttaatgg gggatgaaga aaatttagaa tcaagatgta gtaaatgtcc tagaaaatgc
     9361 ttttagatag ttttcaagag taagatttgt tttgtgtatg aataattgca ataatttttt
     9421 tggttatttt atgtataaac taaaaaaatt attgcaaagt aatattctat ttaatttgaa
     9481 cagacttaca aactataata gtttctttaa ttcaataagt gtatttattt cataagttgg
     9541 tatatgatta gtataattta tactgttatt ggaatttaac caacaagtat ctattcctga
     9601 atttattcca cctaagacat cagaggttaa gctatcccca atcattaagg cagaagattt
     9661 atcatgacaa ttaaactttt tgagagcgta tttaaatatt tcaggatttg gttttgatat
     9721 tttcaactct tcagatacaa ccattccatc aatatatcct tttatttttg aattttcaag
     9781 tcttttcttt tgaactgcag aaattccatt tgttattata acaatagtat actttttttt
     9841 aagatattgt aatatatcga ttgcacctgg aattaaaaat gtacattcac ctaaaaaatt
     9901 taagtacatt ttgctaagag tttcagaatc aacatccaaa gatattttat ttgcaaaaag
     9961 ttcaaatcta agtaatttaa gttcattcaa agttataata tttttttcaa ggtcgagcca
    10021 aagcttatca cttatatttc tatatgactc tatataattc tcaaaattaa attctaaatc
    10081 aaactcagat agaagttttt taaaagcatg tgattcactt ttcttaaaat caaataaagt
    10141 atcatctgca tcaaaaaata taaatttata tgtcttcatg gtttttactc ctttacaaga
    10201 tgactgcaaa aattacttta ctttcactat ttgagtcatt ttgccattta tgctttgttc
    10261 ctaaaggaac ttttacacta tctcctttgg acaaagtaaa ttcatcatca tccataaaaa
    10321 gtttaacttc tccctccaaa acatatgcaa tttcatctcc attatgagta atcctatcaa
    10381 cacaagaaga agtgtttgga gctaaatcca taattgcaaa ttctaaatta ccactagagt
    10441 ctggaattaa aatctcatat ataacttctt tgcttccagg taaaataact ttttttctat
    10501 tatcatgtct tactatcaag ttttttttat ctacttcaga tacaaaaaat gtaaataaag
    10561 gaacgtttag agaagaggct atagatttta atgaatttac agatggatta gcaagacctc
    10621 gttctatttg gctcaataat gatggtgtaa catcagctag ttttgctaaa tctcgaatac
    10681 ttaagttttg tttttttcga acttcagcta ttttttcccc taaatttaaa tcattcatat
    10741 aaatatcctc tctttttaat ttaaaaaata ttaacttaaa ataatcaagt aaaatgatta
    10801 tgtagtatga aattattata acatatagaa ttaggttttg aaaaaactat gttcaatata
    10861 attaaataaa ttaaaatata attgacaaag tggatacaga atacttaaaa tatatttaaa
    10921 taaaattaag caaaagatag ttaatttatg ataggagggg atattatgca aataacgact
    10981 tttggagcta tatttggttt attaatagca attattttaa ttataaaaaa atttcaagct
    11041 gtatatagtt taatgttagg agcatttatt ggaggattag ttggaggagc aaatataaca
    11101 caaactgtag attttatggc aaatggagct atgaatatat caccatcaat tcttagagct
    11161 ttggcatcag gtgtattagc tggaagttta ataaaaacag gggcagtaga taaaatatca
    11221 gaacagattg taaaaatatt tggtgaaaag agggctttat tttcgattgc catttcaact
    11281 atggtacttg ctggagtagg tgtaaatttg gatgtatcta taataactgt agcacctata
    11341 ggattatata taggtagaaa attaaattat tctaaattgt caatactatt agctatgttg
    11401 ggagggggta aagcaggtaa tataatatca ccaaatccaa atactatagc agtagcagat
    11461 aatttttctg tcaatctctc tagtgttatg atggcaaata taattccagc aattattgga
    11521 gttgttatta cagttatttt agcaagtata ttaataaata aaggaaacaa agtacaatca
    11581 tatgaaattt tagagcaaag agaagattta ccaagtttat ttaaatcatt atgtggtcca
    11641 attatagcta tatttctatt gtttttagga aatgtatctc ctatagttat agacccgatg
    11701 atagcccttc caataggagg aatcgtaact ctaattgtca caggaaactt gaacaattca
    11761 agagaatatt tagcttttgg attatctaag atgcaagggg tatgcatatt attacttgga
    11821 acagggacta tcgcaggaat tatacagatg tctgaattac aacagagtac aataggtgct
    11881 ttacaatttt taaatatgcc acaattttta ttggcaccag tttcgggtat acttatgtca
    11941 ttagcaacag catcatcaac agctggtgct actatagcat catctacttt tcatgatgct
    12001 ataataaatg gtgggctatc accgatttca ggtgcatcaa tagtaaatgc tgggtctagt
    12061 gtattcgagc aattaccaca tggctcacta tttcatacta gttcaggtag tataaacatg
    12121 gatataggtg aaagatttaa gttaattcca tatgaagcat tgataggaat agtaatgact
    12181 ataatttcaa catctattca attagtttta taataaatat aaatatttaa tgaaaaaagt
    12241 aggattttgt tattaaatat tgaatttatt atagtaaaaa agaagattgg agttttaaag
    12301 tgaataaaaa aaagattgtt attataggga ttatttattc atttttagta gtattttcac
    12361 ttacaaatat gtatgtaaat atggagtata atctaaatgt atttgaatat attaagaagt
    12421 cacttccatt tacagaagaa gaaaaaaagt ggttagaaaa acacaagaat ttgatttaca
    12481 gctctgacca aagttcacct cctttgagat ataaaggtaa ggaagatgga cagtataagg
    12541 gaattattgt tgatttaata aattctctgt caattcaaat tggtagagat ttttatttta
    12601 aaccaaataa ttggtggaaa gaatcttttg taaattcaat agatgatagt ataaagtttt
    12661 ttgacttgat tccatcaaaa gaaagggcaa ataaatttat atttactgac ccaatataca
    12721 ctttgagtgc aaatatattg aaagataaaa agtcccaaga tataaatagt tacatggatt
    12781 taaaggggaa aacagtagca attccagaag gtgattattc tataaatttt ttaaagcaaa
    12841 aaattcaaga tataaacatt ttgttgactc cagatataaa gactggagtc aaccatttaa
    12901 tgtctggaaa agtagacgta gttgttggtg atgaaccagt attgcgatac tatataaata
    12961 attatggact ttcaaataaa tacagtgttt taagtaatcc tatatatact aaaaaagcag
    13021 ttcttgctgt acctaaacaa tatgaagagc tggttagtat tttaaataaa ggcattttta
    13081 aacttcagaa aaatggagtg tataaagatt taaagaaaaa atggtattct acgtataatg
    13141 aagttgatga tatattgtat gagcgaggaa ttgtgcctag tatttatctt tttataggta
    13201 taattttaat atcaatttat gttttttata gctatacata tttgttaaag atagaaatca
    13261 aaaggaaaac agaacaggta atagaaaata aaaaaacttt agaggcaact tttaatagta
    13321 ttacagatat aataatgctt gtagatgaaa ataacaatat agtagaatcg aacaaagtac
    13381 tatatgactt tatgggtgaa atgagttata agatagcaga tttgattagc atgataaaag
    13441 gtgttattga aaataccttc tctgaaaata ctaataaaac tagtgaaata gaaatacaca
    13501 ataaaatttt aaagataaac acttttcctg tagagtataa aaaaaataat actgagtata
    13561 tagtagttct tattaaagat ataactaatg ataaaatagt agaggcgaaa ttacttagag
    13621 aaaacaaaat gatatctata ggacaattag cttctggggt agcacatgag ataagaaatc
    13681 ctttgggtat aataagaaat aattgctatc tcttaaaaga taacgttaca atggaagaag
    13741 taaatgattg tgttaaatca atagaaagta atgtagatag agcaagtaat ataataacca
    13801 acttgttaaa tttcgcaaga atatcagatg ataatttaga acatataaat ataaaaaatt
    13861 ttattgaaaa tatagtgaaa cttcaatata aaatgttaca gttaaagaat gttgaaataa
    13921 aaattgactg tgaacataat ttaatatgct atataaatgg agaatcgtta aaacatgtat
    13981 ttataaattt aatttctaat tcaatagatg caatacatca agatggaaaa attattatat
    14041 actgttatga aaaaaatcat tgtttattta tagattttaa agataatggt gaaggaataa
    14101 aagaagatgt cctaaaggac atatttaatc ccttctatac aacaaaacca attggtgagg
    14161 gaactggttt aggtttatat attacttata atgagattaa aaagaataat ggagatataa
    14221 gtgttgaaag taaattgggg gttggaactt gttttcatat aaaaattcca ttaaataaag
    14281 aggtgactat ataatgaaaa tactattagt tgatgatgag ctagaatatg gagtggtaat
    14341 gaaaaaaatt ctacaaaaga agggctatct tgtagatata gcactaagtg gtgaagaagc
    14401 tataaatata attaaaaaag ataaaaatta tgatttggtt ttatctgatg ttatgatgaa
    14461 aaatatggat ggagtacagc tattagatag aattaaatct attaatagag atatagaggt
    14521 tatattagtt acaggatatg gaagtattga aaatgcagtt gatgctatga aaagaggagc
    14581 tttatcttat tttataaaaa gtaatcccat tgaaaattta ttagaagaag ttgaaaaggt
    14641 aaaggcaagt aaaatatctg tttctgtaca aaaaaataat tttgaattta ctttggaatc
    14701 taaaaataga gattttaata atatcataaa aatagcaaaa aaagctgctt gtaaagatgt
    14761 taatatatta atcttggggg aatctggtgt aggaaaagat atattagcta gatatataca
    14821 tagcataagt ccaagaaaga atgagatatt tgtacctgta aattgttgtt ctttttcaga
    14881 aaatctattg gagtctgagc tgtttggtca tgaaaaaggt tcttttacag gagcagtaga
    14941 tagtagaaaa ggtagatttg aactttcgaa taaaggaact ctatttttgg atgaaatagg
    15001 agatatacct ctaaatgttc aggtaaaact tttgaggaca cttgaggaca aatctataga
    15061 gaggatagga agtaataaat ctattaaagt tgactttagg ttaatttgtg ctatgaataa
    15121 agaaccaaaa gtggaaatat caaatggaaa tataagagaa gatttttttt atagaataag
    15181 tacaataaca ataactatac caccactaag aaagagaaga gaagacttaa ctactcttat
    15241 agaatttttc ttaaataagt accaaattga acatgataaa aagatacact cgattgataa
    15301 ggaagtaaag gattttttat taaattacaa ttatccagga aatataagag aattaaaaaa
    15361 tataataaat agacttgtag ttttaagtga agaaggtaat ttatcaaaag acaatttaaa
    15421 tttaatatca aataatgtat acatagatga taaaataagt attagatctt taagagaaat
    15481 aagaaaagag tttgaatgtg agtatattga aaaagtttta tctttgtgtg gaaataatat
    15541 ttcaaataca gctaaaaaat tggagattag tagaagacag ttaaccaata aaatatcaga
    15601 gtataatatt aagtgagaaa aaaacttctc attaagtgag aaaaaaattt ctcaaactgt
    15661 attaaaagat aaacagaaaa aatctgttta tcttttttta ttataatttt aaaaattaat
    15721 atttacaata attattgcta aattcaatat tggtgtaaat taaaaatgaa aatttctatg
    15781 acattaatac atagaatata tattttaaat aattggcata gaaaatgctt tatatattaa
    15841 taaacgtaat aaatactttt aattgcgatt aaatatatta agggggattt tcatatgaag
    15901 ctagagctag ggaatatatt tataaaaaat gttgaatttg gagaaaagac agaagtaaaa
    15961 gatggagtac tatatattag tagcgaagaa atagaaaaga tagtattaga agatgaaagg
    16021 attgtaagtg taaatgttga acttgcaaga cctggcgaat caataagaat agctccagtt
    16081 aaagatgtaa tagagcctag agttaaaatt ggagatgaaa gcaaaatatt tcctggaatt
    16141 ataaataaag tgaagactgt aggaagtgga agaacccatg tacttttagg agcttgtgtt
    16201 gtaacttgtg gaaatatagt tggatttcaa gaaggcgtaa ttgatatgag tggtcctact
    16261 gctaaatata cacctttttc aaaaacaaat aatatatgta ttgttataaa agcaaaggat
    16321 ggtatagata ctcatgatta tgaagaagca gctagaattg caggattaaa aataggtgca
    16381 tatgtaggtg aggcaggaag agaagttgag ccagatgaag tcattgtata tgagacaaag
    16441 ccattattaa aacaagtaaa agaatatcca gacctgccaa cagtagcata tgttcacatg
    16501 ttacaatcac aaggactttt acatgacact tattactatg gggtggatgc taaacagata
    16561 gtgcctacat ttatgtatcc aactgaaata atggatggag ctataatatc tggaaactgt
    16621 gtagcaccat gtgataaggt tacaacattc catcatttaa ataatccagt tatacatgac
    16681 ttatataaaa gacatggaaa agatttaaac tttataggag ttattttgac taatgagaac
    16741 gtattcttag tcgataaaga gagaagctct gatatggtag ctaaattaat agaattttta
    16801 ggagttgatg gagttctagt gacagaagaa ggttatggga atccagatac tgacctaatg
    16861 atgaattgta gaaaatgtag tgaagttgga gcaaatgtag ttttgataac ggatgaattt
    16921 cctggaaaag atggcaagag tcaatctata gcagacgcta ctaaggaagc agatgcagtt
    16981 gtttcttgtg gtcaaggaaa tctagtggtt catttcccag caatggaaaa aattatagga
    17041 actttagatt atgttgaaat gatgataggt gggtataaag gatgcttaaa tgaagacgga
    17101 agcatggatg cagagctaca aattataata gcatcaacta tagcaaatgg ctataatcat
    17161 ttgacagcaa gatattatta aataagtatt tgaatataaa gttctgttga tgtaatcatt
    17221 ggtctaactg atgtaataac tataaagtga tttggaggat taagagatga gtaaaatcag
    17281 agtggttcat tatataaaca atttctttgc tggtataggt ggagaggaaa aagcagatat
    17341 tccgccagaa aaaagggctg gtgtagtagg acctggaata gcatttcaga gtcaatttaa
    17401 tgatgatgca gagataatct caactgtaat ttgcggagat acgtattttg gtgaaaatat
    17461 tgagagtgca actcaagaac ttttaaaaat gataaaagaa gaaagccctg atttatttat
    17521 tgcaggccca gcatttaatg caggtagata tggagtagct tgtgggacta tttgtaaggc
    17581 agttgaagaa gagttaaata ttcctgtaat tacaggcatg tataaagaaa atccaggtgt
    17641 agatatgttt aaattagatt tgcatatagt gtctacagga aattcagcag caagtcttag
    17701 aaaggtagtt ccaataatga cgaaactagg tcttaaattg gttagaggtg aggaaatagg
    17761 acctcctgaa gaggaaggat atataatgag aggaataaga aaaaatttct tccatgaact
    17821 tagagggtct gaaagagcaa ttgatatgtt ggttaaaaag atgaaagggg aaagctttga
    17881 aactgagtat ccaatgcctg aatttgatag agttacacct atgaaacctg ttaaagattt
    17941 atctaagata aaacttgccc tagtaacttc tggagggata gttccaattg ataatccaga
    18001 caaaattgaa tcttcaagtg ctactaaata tggaatttac gatttaacag atatggattc
    18061 tatgtcaaat aaagaattta caactataca tgggggtatg acagagcata tgtccttgaa
    18121 aatccaaatt tagttgtacc actagatgta gttagagagc ttgaaaaaga aggtgtaatt
    18181 ggagaattag tagattattt tataactact acaggaacag gaacgagtgt tggcaattct
    18241 aagagatttg gagaagagtt ttctaagaaa ttgttagaag atgatgtaga tgctgtaatt
    18301 ttaacttcta catgaggtac ttgtactcgt tgtggagcaa cgatggtaaa agagattgag
    18361 agagctggta tagcagttgt tcatatatgt acagtagtac caatatcact tacaatagga
    18421 gctaatagaa ttgttccagc agtagggata ccatatccac ttggaaatcc tatgttagga
    18481 gaagaggaaa gtaaaaaaat tagaaagaat atagttttaa aagctttaaa tgcactaaca
    18541 gaagatatag aagaacaaac agtatttgaa taataaaaat acaacacaac actgaaataa
    18601 aaaaagatat caaaaaataa ttttttaaaa ttattttacg atatcttttt ttattaggta
    18661 aattcgaaat ttgcattttt ttaaattaaa tttataaaag tgataaatta gtttattata
    18721 atattgatac acaaattcaa attagatata ctatgaaaag cgagattatt acattttgga
    18781 acaaatattc aacatattag atcatattaa ttgaacagaa aaaattaact ttatataata
    18841 attagaataa tgataagaaa gaaggtgtat atattgattt caattgccat ttgtgatgat
    18901 gaatcctata tgctaaatca tttaaaggaa aatatagaat tatacatgaa gcagaagaat
    18961 ttattatata atatagagct ttttaataaa gtagaagatt tactatgcaa tcatgaaaag
    19021 tttaatattg tatttttaga tatacagatg gaagagatta acggaatgca ggcagctaga
    19081 aaattaaggt catatggtaa tgagtgcttt ataattttcg ttacagtttt aaatgaattt
    19141 gtatttgatg cttttgaagt agatgctata aattatctga taaaacctct atctaatgag
    19201 aaactatata aaactttgga taaaatagtt acaaaacttg atgataatga aagtaattat
    19261 atcacaatac aaaaaggtta ttcatattgg aaattaaaac ttgctgatat tttatattgt
    19321 gaagttataa aaagaaagat ttatgttcat ttaaagaaag agactgtaga ttattatgag
    19381 actattgaaa atttagagag aagtttacca acaaattttt ttaggtgtca tcgtagttat
    19441 ataatcaatt tacaatatgt atatggatat gaaaatggta atgcagttat ggaaagtgga
    19501 gatagaatac ctgtttctag actacgtcaa caaatatttt caaaagttat gcttgagttc
    19561 atgaaaaata ggaggatata agatgattaa tttattttct tccgatttat ttttaaagta
    19621 cagttttttc ttctctttta ttgtatatag aattttaatg gtaatagtgc aatactattt
    19681 tctaatcaat tttacaaatt ttaattcaaa attttggtgt tttattttat attcgataat
    19741 ttcaattttt ttaatcatta taaatacata ttttaattta tataatttat tttcttcaca
    19801 gattctattt tttcttatga cttttttatt tgtaaagtac ataataaaac aatctactgt
    19861 tttatctata gtatcaactt tgttagtata tttaattgaa caattagtat atggatttac
    19921 agctccatta aattacttga tatttactag tgatataaat acagatattt ataaatttga
    19981 tataaatatg ggactatctt ctttaattac tattataata gctggattta tatattggta
    20041 tagttctaaa aagtttaata ttaaggtcat gaactttgat aaatatatag caattttgat
    20101 gattccattg ttgcttataa tattatttat gcaatcattt gaatatagtt caaatataaa
    20161 tatagataca agtcttggga ttgtaaagct gctattaaat acttctataa ctgaagaaat
    20221 tcaagctttt cttttttcta taattggaac tatatgtgta tttttttctc tatttacctt
    20281 taagaaacta attcaagctc tcgaagatga caaggagagg gcaattatga atcaacagat
    20341 tcatgctcaa aaaaactata ttgaagaagc gaaatcacga ttatcacaaa ctatatcctt
    20401 tagacatgat tttaataatc atttagctat tgtcaatgga ttgttgaaaa aagaccaaat
    20461 tttaaaagca caagattatt taaataagct tgaaaaagta acaagtgacc tatcattttc
    20521 ttgtaataca cagaatattg ttattgatgc tcttttcaac aataaattaa gtatagcaaa
    20581 acaattaggc atagaggtag attgtgaagt aattataccc caaagcacta acatgaacga
    20641 ttttgaccta tgtatagtgt ttgctaatgc tattgacaat gcaattaaag cttgtagagt
    20701 tgtagataaa caaaataggt atttaaagct ttccactaag ttagagggtg gattttttat
    20761 gatagaaata aaaaatagct ataatccaat aaataattat acaagtggct caggtatagg
    20821 tcttttaaat ataaaagaaa ttgctaaaaa atatcaaggg gctataagta tagataagac
    20881 atcaaactat tttcaaataa atgtattgct agttatttca ttacattgcg ctagtatttg
    20941 agaacaattt cattgaaaat agtatttgta agctatatta tgtacttgaa tagagaaagt
    21001 ttgatatata gaaatgagga ggttactaaa atgaaagttg gaaatataaa tggtcaagca
    21061 ccaattacaa atggtttaga tagttgtcaa agtgaggtac aaggcttaga acaaaagaaa
    21121 aaagcattac aggatgaaat agagaaagta agaagcgata aaagtattga tggtgaaacg
    21181 gccaaattaa aaatagaagc tttaaaaaaa gaaatggaag agattgaaaa taaaattcaa
    21241 gagttaaaag gaaataaagg aaaaaaaaca aataaagaag aaaataacgt ttcagaagta
    21301 aataataatc tattagagag aaaaaaagaa ccttctaata atgaaaatgt aaaacaatta
    21361 tatgatgttt ttgaaagaag caatgtagac gaacaatggg ataatactta tcgtgttctc
    21421 caagatgata aaaacttaaa agtaaaattt aatagaccta tatagtttat ttataaaaat
    21481 agttaatatt ttaattatca ccacttttta gaagaataca cactttattt taaagaccca
    21541 catatttatt tacagttagc acatttatat gtggttttat aactattatt tataagtcta
    21601 tattgataac ttttacatag tatataatgt ttaaatactt attcaaattt atctatacat
    21661 aaacaaaaaa agagatttta aaatctcttt ttagattgtt gacttatggc tttttgattt
    21721 aataaaatca agaagccgtt tgaattttat ctgttggctg atacccttct gatattgaaa
    21781 caccattttt gtttccaaaa tcgtttaaaa ttaagaactt attatgaatg actatttcat
    21841 tatgaacaat aagcagataa catgaatctt caatcaatgt tttaacagta gcattaaatg
    21901 cttgcttata cagttctatc gtttgtttga actgtccatt aaagtaaata tgagtcaata
    21961 acataactat atctacacaa attaatataa attttttata ctgtacatta tctaactgtt
    22021 gattatctgt attacaacat gattgaattt aaaaagccat caacacatag aatgttgatg
    22081 gcctgaaaat agatttaaaa tctctttttt attatatatt aattattttt taaatttata
    22141 ttttttgcat cagattttct aatagctaag tcaaaccctc taaatctaat cactataggg
    22201 tcattaagag gagctatctt tttcacttca acttcagtgc catctattag tcctaaggct
    22261 agaagtctct tcataagttt ttcatttcca gctatattgt ctataattcc cttttgtcca
    22321 agttttaagt tgtaaacagt cattattaac acctcctaat gaaaatcatt atcaaacttt
    22381 atatttataa tatataacaa aaagagcaaa ttgtcaatat ataacaaaaa ataaacatac
    22441 taagttagta tgtttataaa aaatagtata catgggatac taatagcatc tagcaaaaaa
    22501 ccgcttacta atggtacaac caaaaaggct tttggagaat caccatattt ttgtgtcaaa
    22561 gaactcatat ttgccaaagc gttcggagta gctcctattc catgtccaat caaaccactt
    22621 attatgatgg cagaatcaaa atcttttcca agtactctaa agcaaataaa tattgaaaat
    22681 aggattataa agattacttg aaaagttact attaagagaa taggaggtaa taatgtagat
    22741 aattcaaata aatctatatt cataagtgat aaagttaaaa aaattcccaa tgaaagttct
    22801 tttaaaaaat ctataagttt aaaatttaat tctagtatat ttatcttatc atttaaattt
    22861 ctaaagataa cagccgaaaa catacaagtt acaacagagg gtaatagtat attaaacgtt
    22921 atatagaagc atctacttat aatttctcct gtatttatac aaataaatat gagaagaacc
    22981 tgttccaaaa acacagatgg tgttattgtt tcggagaagt tattattttt tatcctattc
    23041 ttatttctaa aaaatttact tccaaatctc tttagatttc tattatatct aggaatcgac
    23101 aagtctatat ttgatgatgg ttttaattta tatttattta ttagaaattt agctacagga
    23161 catcccaata taccacccat aataagtcct attgttgcag cagataatcc aaccccaact
    23221 gctccttcta taccgagatt ttctattgta agtccaaatg cagcagaata accatgacca
    23281 ccttccatag atacatttcc acacataagc cctaaaagag gttcaagttt tataatcttt
    23341 gatattgtaa tagctaatat attttgacaa aatgccaata ctccacacaa aatccaatat
    23401 ctaaataata cactaccccc tttctttata agatttatgc ttatttcgag tcctatagtt
    23461 gtaaaaaaga aggttataaa atttggcatt aaatttccac ttatagatat atctgctata
    23521 ttaaaatatt taaaaaataa atttagaaaa caaaataata gacctcctat tactggtgca
    23581 ggtatacaga aatcgtttaa aaagttaact ttattcttca ataaattacc aattaaaaag
    23641 aagaatatag atagtgtcaa ggtttgcact atatcaaaac ttaaggtaat caaaataagt
    23701 cctcctttgt aattcaaagt tttaattata taacttaaat tcttatgtat tgaaatttta
    23761 ttatcaaatg tatattaata aatgtatatt aataaatgta tattaaaaag aatcagtaga
    23821 tataattaga tagtcataaa ttaaattaaa atattttaat gagatatgac ttttttagaa
    23881 tgaaaaaccg tagtatattg atataataga aataagactt aaaaatctgt tgatagtatt
    23941 atttataagt acagtaggag gataaaatgt ttgaaaattt acctaagata gatttacatt
    24001 gccacttaga tggaagtgtt agagtagaaa ccatgcttga tatagctatt aaagagaaaa
    24061 tagatttacc ttcaaataat atggatgaaa taaaaaaatt agcaaaggtt tcttttaatt
    24121 gtacttcact agatgaatat ttagaaaaat ttgatttacc cttaaaagta atgcaatcta
    24181 aggaaaattt aaaaagaatt acttttgaac ttttggaaga tgcaagtaga gaaaatgtaa
    24241 aatatattga aattagattt gcaccattac ttcacaccca aaaaggtatg agtgttaaaa
    24301 atataattga gggtataatt gaaggaatta gagaagctga aagtatttat gatataaaag
    24361 gcaatttaat attaggttgt atgagaacaa tgacctcaaa agaggcatta ttagtaattg
    24421 aagaagggaa atcatttgta aataaaggtg ttgtagcagt agacttgtgt ggtccagaga
    24481 aagagggatt ttgtaaggaa tataaagatg tttttaaatt agcaagagaa tatggatata
    24541 aagttacaat acatgcagga gaagctgcaa gtggagaaaa tgtattggat gctataaata
    24601 ttttaaaggc ggataggatt ggtcatgggg taaaaattaa agaccatgaa aaggcgtata
    24661 atttagttaa agataaaaaa atattgcttg aattatgtcc aactagtaat gtacaaacta
    24721 agacagtaga ttcttatgag gtacatccat tttatacttt ttataaagat aatttacatg
    24781 taagtataaa tactgataat agaactgtat cagatataaa tttaagttca gaactaaatg
    24841 ttatatttga tacttttaaa ctaggattag aagactataa aataatttat agaaatgcag
    24901 tagaagctag ttttgcagat aaagaaacta aagagtattt gaatagttta atttaataga
    24961 taaaaatatt taaactttaa attaagctat taaattgaca aaaatacatt gtattaggag
    25021 aaaaaatgtg aaagattatg aagatgttgt ttatattaaa ctagtcaaaa aagaacttga
    25081 agaatggaag aaaaatatat taaagaaacc ttctatattt gacaaagcat caaagggtat
    25141 acagaataaa tttaatggag tattgccaga taaatatcat gaaataatta cttcttctat
    25201 aaaagtaatg acaaaaaccg tactgtttgg atataaatat gctacaaagc caccacttag
    25261 aaatatgtca ttagaagaaa gagaaaaatt agttttagaa aaagctaaaa cttacaagac
    25321 cacagcaatg attgaaggag caggaacagg ggcaggagga atcctcttag gtttatctga
    25381 ttttcctttg cttttaggta ttaaagtgaa atttttatat gatgtagctt caatatatgg
    25441 atatgatgtt aaagattata gagaaaggat ttatatatta aatatattac agttggcttt
    25501 ttctagtcaa cagcatataa acaaaacttt taaattgatg aataactggg atgaatatgt
    25561 aaatagtcta ccagaagaca tcaatgattt tgattggaga acatttcaac aagagtatag
    25621 ggattattta gatttagcta agtttttaca actaatgcct ggaataggag catttgtagg
    25681 attttatgtg aatggaaaat taattgataa attatgtgaa actgctgtgt ctgcttatag
    25741 attgaggatt cgagagctta agttataaga aaaattataa cataaaaaat tagttataca
    25801 atatatctat atgtatctaa ttttgcattg ataaaaacaa ttatggataa aaggtaaagc
    25861 atgatagaat ctaatgtaga ggtttgtatt ttaatggaaa aatttagttt ttattgctta
    25921 agatacaaat tgaattacga agagattgaa ttatgaagag aagtaattgg gaggaatatt
    25981 ttcatgacaa atttgccaaa acaatttgat agcttcaatg aagctagaca aaaaggattt
    26041 ataaatgcaa aggaacttaa ggaaagtggg aaaaagatgg ttggagtttt ctgtacattt
    26101 actccagttg aaattccaat ggcagctgga gcaactgtag taggtgtatg cggcgttagt
    26161 gaagagccaa tacctgatgc agaaagggtg cttccaagaa atctttgtcc tttaattaaa
    26221 tcaagctatg gacatgcaat aacagatacc tgtccttatt tctatttttc tgatttgttg
    26281 ataggagaaa ccacttgtga tggtaagaaa aaaatgtatg aagaacttgc aaaagttaag
    26341 ccaacatatg taatgcattt gccaaatact tcaaaaggag aatttgccta taaactttgg
    26401 aaagatgaaa tgataagatt aaaagaagag gttgagaaat ctttaggtgt aactataact
    26461 gaagaagata taagaactgc tataaaagat aaaaatgaag aaagagaact tttaaaagag
    26521 ttttatgcac ttggtaaatt acaaccatct gcacttacag gccttgagtt acataatgtt
    26581 ttatatcaag caggttttaa atttgaccgt gcagaactta aacattcttt aagaaaagtt
    26641 atagatgata tgaaagaaag atatgaaaaa ggtgaatgtc ctgttcaaaa agataagcca
    26701 agaatattga taacaggttc tcctattggt ggaataagcg aaaaaatagt taaaacttta
    26761 gaagatgcag gggcatcagt cgttgcatat gaactttgtg gagctattag atcaaacgat
    26821 ttattggttg atgaagaaat agaagatgta tatgatgctt taacacaaaa atatataaat
    26881 ataggttgtt cttgtatgat gaataatgac aatcgtattg aattattaga tagaataata
    26941 gatgaatata atgtagatgc tgtaatagat gtagttttac aagcatgtca tacatttaat
    27001 atagaaagtt atagaataag agaatttgtt acaaaagaaa aaaataagcc atttatgtct
    27061 cttgaaactg attattcaaa atcagatact gaacaattaa gaactagatt tgaagcgttt
    27121 gtagagatgt tgtaggaata aataaaagta ggaggaacta tgtttagtat aggagttgac
    27181 tcagggtcag tggcaacaaa gggtgtgcta tttgatggtg aaaaaattat taagaaaata
    27241 attataccaa ctggatggag ccctaaaagt acatctaaac aggtctatga gttgctaagt
    27301 agtgaaattg acaaaaaaga tataaaaaag gtggtaggta caggttatgg aaggggagta
    27361 atggattttg ctgataagaa agtaacagaa ataacttgtc atactagagg tatttacttt
    27421 ttaaacaata acataaggac tattttagat gtaggtggtc aagatagtaa agttataaat
    27481 ttagatagag atggaaatgt atttaacttt ataatgaatg ataagtgtgc tgcaggaact
    27541 ggtcgatttt tagagattac ttctaacctt ttaggaagcg atattgaaag tatagataca
    27601 ttagctaaag gatatgaacc agttaatata tctagtatgt gtacagtttt tgctgagtct
    27661 gaaattgtaa gtcttctagc tcaaaacatt tctactggag aggtagcagc agggatactt
    27721 aaatctattg caaataaatc cacctcaatg ttagcaagag gtgaggtaat agatgaagtt
    27781 gcatttactg gagggcttgc aaaaagtaaa gaactagtaa aaatgataga agaaatactg
    27841 ggtaaaaaaa tttttattgc agaagatact caaataatag gagctttagg agctgctgta
    27901 ataggattta gataaaaaca tataaaaaga aaatgagaag ctgaatttat tataaataaa
    27961 ttcagttttt tattttattt tatttattta taaaggaaaa ctttggtata attgatttaa
    28021 atgattgtat atttgtaaat acttgatatt tagtcatata taacattata attttaaaaa
    28081 ttagctcaaa ataaggggga gaaagcgtga aaaaatttac ttcaaaaaaa gtaacaaggt
    28141 ttgttgcgct gtttttaata tctattttag taatgtcaac aattcctgta tcagctgaca
    28201 atagcaatac attgaatcag ataaaaaaag cagaatacag tgagacgtat aaacaatatc
    28261 taaatgatgc taaaaatgga cgtacagaaa aatataatgg gattatacca aatccatatc
    28321 agttggaagg tactcaaatc caaagtaaag gaagaacagc tccaacatct tatgacccta
    28381 gaaaattagg tcttatgaca tcaataaaaa atcaagagga tttaggaatc tgttgggatt
    28441 ttgctgcaat ggcaacctta gaaagtttct taaagttaaa taattatgga gactatgatt
    28501 tatcagaaga acacttaaga tggtgggctt cagatggtga atatggatgg tctgtaaatg
    28561 atatgaatgg tgctttaaat tatgaagcta tgggatattt aacatcttgg tcaggtccta
    28621 aattagaaaa agatatccca tacaatggta gagtatctaa agcacaagga gcaaaaaaac
    28681 caactaatat gaatacagca cctactgttt ttaatgtgac agatgctgtg tgtgtaagca
    28741 atgacataaa ttctacaaaa aatgctatat tacagtatgg agcagtaaca tctggttatt
    28801 atgaagatat taaatatcaa agtgatgacc aaaattcata ttattgtcca acaaaaagtt
    28861 ttaatacaaa tcatgctatt tcaattgtag gttgggatga taactattct aaagataatt
    28921 ttaatgcaaa tattagacca tcaaaaaatg gtgcttggtt aataaaaaat agctggggag
    28981 attataattc tgagggtgga tatttctgga tatcttatga agacaagaca cttatgtctg
    29041 atatagataa tttttcaatc aaaggtggta aaaaaccaaa tgatgatgag aagatgtatc
    29101 aacatgacta tgcaagtatt gtacctttaa tttcaaaaaa gataacagct gcaaatgtat
    29161 ttgatttcaa tagaggtgat gaaactctaa aatctgtaat gttcttaact gaaagtatag
    29221 gagctaagta tgaagtatat tatgctccag tagtaaatgg tatacctcaa gaaaacaata
    29281 tgaaaaaatt aaaagaaggt actgcccaat attcaggata cataacagtt ccaattgatt
    29341 cttttgatat accagaagga aagggtgcaa ttgtagtcag catagagggg aaaaatggag
    29401 agtcaactat aggttctgag tcaaatgtac caggatatga tacatttaaa gcaaaagcta
    29461 atttaggtga aagttatatc atagataata ctggaaaatt ctttgatata aatagagata
    29521 gtaacttcta tccgtgtaat tttactataa aagctgttac agaaaagtct tctggtgaga
    29581 gtatcccaaa tgagtcttta attggtagtg atagatatga aactgctatc aaagttagtc
    29641 aaaatggttt caattcttca gaaaatgtag ttttagtaaa tggcagttca atagtagatg
    29701 cattggcagc aactcctttt acatctgcta taaattcacc aatattattg acacaaaaag
    29761 aagctttaaa ttcaaaaact aaagctgaga tacagagatt aggtgctaag aaagtatacc
    29821 taataggtgg agaaaattct ataagtaaag aaattgaaca acaattaaaa agcttaaata
    29881 tatcgataga gagaatatca ggaagtgata gatacaagac aagtttatta ttagctcaaa
    29941 agttaaatgg tataaaaaat gtatctcaaa tagcagttgt aaatggagtg aaaggattag
    30001 ctgatgcaat tagtgtaggc gctgcagcag cagaaaataa cataccaatc atacttgcaa
    30061 atgaaaagag cgaattgcaa ggagctgatg aatttctaaa ttcattaaat atagagaaat
    30121 cttatattat tggaggaaca gcatccctat caaacaatct agaaagtaag ttaaaaaatc
    30181 caactagatt atctggtagt agtagagacg aaactaattc aaagataata gataattttt
    30241 ataaaaaaga tactttaaaa aatgcatttg tagttaaaaa tggaatcaag aatcaaaatg
    30301 atttaataga tggattggca gttggtcctt taggagcaaa aactgggtca ccagtaattt
    30361 tagttggtga taaattagct gatagccaaa aagaagttct taaaaataag actttagaaa
    30421 aagtaactca agttggtgga ggagcaaata aaaatgcatt taaagagtta gtaaaattaa
    30481 aaagtgctaa atagagtact taagtattaa catatattag tgtgtattag taacttatct
    30541 taataaaagc tgaaaataat tacttcaaat tattgataaa taagataatc aatgattgta
    30601 aagttttgtt ttcagcttta aatttatgta gtataagttt aaaaacataa aaaagggtta
    30661 ctttatatag aaatatagaa aatcttacat tttatatata aataacccat atttaattaa
    30721 ctttttatag tgttctaata gatattattg aacttaatgg taaatataat gtgtaagttt
    30781 catttaaagt tggattagat tcatctatat atcttgagca aagtgtaatt gataagctat
    30841 ctgcttctat aatttcacca tatagaggac aactgctaaa gtaagaatgt acttcaacat
    30901 atttatttaa gttttcttga acataatcgt aaaaacggtt ttttgtagta gtagccataa
    30961 aatcaactcc tttatttttt attaaagttg aaacttttaa aaagataaat atgattactt
    31021 ctattagaaa ctaagttaaa aaataagcaa atagatatga aaattagaat aatatattat
    31081 ttatatctta attataacac tagataataa aaaatgctat ataaaattca gaattttcga
    31141 aagtttttaa gcttattttt aaatatacta ataatactat tgacattaga tagaaaaagt
    31201 attatattga ctatataaat tattttagtc aaactggagg gaaaagatgc ctaaatcata
    31261 ttctgataaa gaaagagagt atataataaa aagacttaaa gaagaagcaa gattgtgtat
    31321 ggagcaatat ggtattagaa aaactactgt tgatgagctt gtaaaacggg taaaaatacc
    31381 aaaaggaact ttttatctat tttttcaatc aaaagaattg ctcttttttg aggtattaag
    31441 agatatacat gactctatac aaaaagaaat cttatatgag ataaatagag tagatgaaag
    31501 tattacatgt gaacaattga cagatatatt tatgaaattc tataggatgg ttgatagtac
    31561 ttcaatttta aatctcatga taaatggaga atttgagata ttggtgagaa agttaccaga
    31621 ttctataatt gaagaacact ttagacatga tgactttgaa attggagaga ttatatcttg
    31681 cataccaaat gcaaaaaata aagacataga aagctttagt ggagcattta gagcagtttt
    31741 tcttaccatg ctatataagc gcgaggttgg aagtaattgt tttgaagatg ctttaagatt
    31801 aatgataaac ggattagtta tacaacttat ggaatagaat ttaaattttg tttgataata
    31861 acttttatta aaaattatta acaaacaaaa aaattatatt ttattgacca tatagtcaaa
    31921 atagtcaaaa atttgaaagg gtgatattga atgattaaag ttgatgattt atcatttagt
    31981 tatacagaga gagatttttt acaaaatatt aactttggag taggaaaagg ggaaatacta
    32041 ggatttttag gaccatcagg tgcaggaaaa tctacattac aaaagattct aattggaatg
    32101 ataactaatt atggaggaag tgtcattgta aatggagtag agagtaaaag acactcaaat
    32161 aaattttatg aaaatatagg agttgatttt gaatttccta gtttatatga aaagttgact
    32221 gcaatagaaa atttaaaata ttttgggtct ctatattcta aaaaactact atctattgat
    32281 gagttattaa aatcagtagg actagaaaat gaagcaaata aaagggtatc tgagtattca
    32341 aaaggtatga aatctcgatt aaattttata aaagctttat tacataatcc agatatttta
    32401 tttttagatg aaccaacaag tggtcttgac ccatcaaata gcaaggttat gaaagatata
    32461 attttatcag aaaaatctaa aggtaaaact attattttaa caactcataa catgttagat
    32521 gcaacagagc tttgtgacag agtagcgttc attgtaaatg gtaaaatatc tgctttagat
    32581 acaccacata atcttattat gtcaaaagga gctattaaag ttagatatac ttactttgat
    32641 aatggagaaa aaacttctga atgttttctg aacaatactg ctaatgataa aaatttgaat
    32701 atgcttattg agaaaaataa acttttatca atacatagta gtgaaccaac attaaatgat
    32761 atttttattg agataacagg gaggaattta caatgaggct aaaaaatctt attttaggag
    32821 atataaagtt tcaatttaag tatggttttt attttttata tcttttttta agtattatat
    32881 atatttgtat tatcaatgta tttccaactt ttatgagaga aaaaatagct ataattatga
    32941 tttattctga cccagcagca atgggattgt tttttatggg agctattgta cttcttgaga
    33001 aaagtcaaag ggttttaaat tccttagctg tatctccagt aaaagtatct gagtatattt
    33061 tatcaaaggt aatttcatta ggagtaatat ctagtattgt agctatgttt attgctatta
    33121 cattaaattt agataatatt ataatatcaa ctataggtac ctttttttct tctattatat
    33181 tttctttgct tggattgata cttgcaagta aagcatctag tttgaatcag tttattgttt
    33241 taagtattcc tattgagatt atatgcttta ttccaccaat actcaatgta cttcttgaca
    33301 caaaatcata tgcaaatttg taccctttta atatatgtat ttctcttatt agtggagata
    33361 aaaattttat aatgattaat attttaattt taatatcaat tataataata atttatttta
    33421 taacttatta ttttatttgt agcagttgga aaaaggtagg tggagtaaaa ctatgataaa
    33481 gattataaat gcgtttaaac aagagtttga acaaattaag agagatgcta tgctttttat
    33541 agtatgtgtt tctccaatat tatgtggagt atttataaaa tttggaatac cattaataca
    33601 gaatatatca cttaacaagt tttattatca attaaattta gagccgtatt tcttgatgtt
    33661 tgatttactt ttagctttta ttacaccttt tatgttcttt tttgcttcta caatggtcat
    33721 attgggagaa attgatgaca gcatttcaag atatttaata gtaactccgc ttggtaaaac
    33781 tggttatctt atttcacgat ttggaatacc aggtatctta gcatttatta ttactatgat
    33841 tctacttatc tttttttctc taactaaaat ttctttcttg ttaaacttat caatttcttt
    33901 attagtttta ttacaaggaa ttattatatc aatattagtg atttctttat catcaaataa
    33961 actagaagga atggtaatta cgaaattctc aggtgttttt atgatgggta ttttagcacc
    34021 attttttatt ttaaataaag cacaatatat tctgttcttc ttaccaactt tttggatatc
    34081 gaaggcattt aaggaagata attatgtcta tatgtttatt tcaattgtta tatcattaat
    34141 atggatttta ttattattta aaaagtttag taaaaaaata gttaaataag aaaatttaat
    34201 atataaatgt aaggttgact tgacagtaat gttgaaaaat gttacattta agatgtaaag
    34261 ttaaccttac atgaatggag caaatatgaa aaataaaata aagatattaa gagaaaaatt
    34321 aggattgaca caagaacaac tagggagatt agttggaaca tctagacagg ctataaatgc
    34381 tatagaaact ggtaaaaatg aaccttcaat atggttggca tatgatattt caagaatttt
    34441 taatgaacca attgaaagtg tatttttatt tgaagaaagt gaaagaaaat caagagcaca
    34501 gataagtagg ggagaatatt atggctataa gaaagataag aacatttgat gatgaaattt
    34561 taagaaaaaa gagtaagtat gtagaaaacg tagataataa gataagagaa atattaaatg
    34621 acatggcaga gaccatgtac aatactccaa atggaggagg attagctgca tgccaagtag
    34681 gagtattaaa acgattagtt gttatagatt taggagaagg acttattaag cttgttaatc
    34741 ctgaaattat taaacaagaa gaggaacaaa ttgttgttga aggatgttta agttttcctg
    34801 aagtatgggg taaattaaaa agaccaaaaa aagttacagt gcaagctcta aacgaatacg
    34861 gtgagaaaat agaaattaaa ggttcaggtt ttatggcaaa atgtctttgt catgagatag
    34921 accatttaaa tggtatagtt tttacagata aaattattga acatgtaaaa ttgtaagata
    34981 gattggttat tgaatttata aaatatttta tagtaaggag ttaaattatg agattatggc
    35041 ataaggattt aattgatgta ttacctaaaa atcaattagt aagtcaatgg agagagctac
    35101 ttgctataaa aggttctata gataaaaaag gtactccaaa ccatctatta gtgaataaag
    35161 tattgaatta tagtatagat gaatttaaat tttatacaaa aattgtacat gatgaaatgt
    35221 taaaaagaaa ttataaacct aatgaactta aatatacaag tatattaaaa tggaaaaata
    35281 gaaattttgc aaatgatata tctaatgaac atagtttaaa tttagaaaat ttatatgatg
    35341 attggcataa taaaatgtat ttaaagcaat gcttatataa tttagaagaa aaagcaacat
    35401 gtggaggaat accaataaat gaatggaata tattactttg taaatatagt aaagattatg
    35461 aattgtggtc tggaaatatc atattttaat tactatagat taacattata gtattattgt
    35521 atataaagag gtgattattt gtataataaa ataaaatata ttccaataaa ttgtgaaata
    35581 gcttgtaata aattaaaaag gagtatgcca tataaatggg atttaaatat ttatcgtgga
    35641 tgtgagcatg gatgtaaata ttgttatgct atttactctc ataagtacat caactccaat
    35701 aattattttg aagagattta tgtaaaaaca aatatagtag aaaaacttga gagacaactt
    35761 aaaagcagta aatggaagaa agaagtaatc aatataggag gagttacaga tagttatcaa
    35821 ccaatagaag ctgactataa aattatgcca gaaatattaa acctgctgat aaaatacaag
    35881 acaccagcta ttatttctac aaaatcagat ttaattttaa gagattacga tttaattgat
    35941 aagctatcta ggattacata tatcaatgta gcatctacaa ttaccacagt aaatgaagat
    36001 acacaaaggc ttattgagcc aaatggtgtg gattcaatga gacgatttaa aatgttaaaa
    36061 gaatttagaa aaactaacgc atcagttggt ctacatatta tgccaattat accatatatt
    36121 acagatgatt ttgataatat aaattcgcta tttagacatg caaaagaatg taatgtacat
    36181 tatgttttac ctggggcttt atacttaagg ggtataacta gaggtgtttt ttttgacttt
    36241 gttaaaaaag agtttcctga attatttgat aaattatcaa tactatatag tgcaggttca
    36301 cttaataggg agtataaaaa tcaattgtat aaaatggtta atgaacttag atataagtat
    36361 tctctatcaa gcagttactc taaaataatg aaggaaaagt taaaaaactc aggagatgta
    36421 cagatatctt tttttgatta gttttatata aaaaaatttt ttttactatg atgattaaaa
    36481 tttattaaaa ttaaaattta ttgacaaata taaaatttaa atatataatt aattcataaa
    36541 ataaaaatat gaaaggatga tgttgttcgg tgatatttga tatcataaaa tcgttgatat
    36601 aagtattgct ggaaaagagt gaataaaatc aaatttaata agcaaacaaa gtaaagctat
    36661 agttttattg ttgtgcttaa aaatatttgg ttctatttta ctcttattta aactcatctt
    36721 tttgaagtta aaccacagag taaactctgt ggttttttta ttttaaaaat aaattttaag
    36781 gagtggtatg ttttgttaaa caaattatgt atgtatttag aaagaccaga gctttataaa
    36841 caaagtgaaa ttaatttttg ggatgatgag tatatttcaa agcaattatt aaaagcacac
    36901 ttagacacta attttgaagg agcaagtaga aattttaact ttatcgagga ttctgtaaat
    36961 tggatagtta cagttgcaaa tccagctaat tatcctaaat tacttgattt aggttgtggt
    37021 ccaggtttat atgcagagaa atttgcacaa aaaggttata atgtaactgg aattgatttc
    37081 tcaaaacgtt ctattaacta tgcacaaaat agaaataagg agactaattt aaacataaat
    37141 tacttgtttc aaagttattt aaatatgaac tataatgagg aatttgattt ggctacttta
    37201 atttattgtg attatggagc tttgtcaact gaaaatagaa ggttattaat ggaaaaaatt
    37261 tatgatagtt taaaacctgg aggaaaatta atattagatg tatttacaat aaataaatac
    37321 aataattttg aggaaattaa atattgggaa ataaataaag atggaggatt ttggagtaat
    37381 gaaaaatata tgtgtctaca agataattgt aaatacaatg attataatac attagaacaa
    37441 actcttgtaa taaccgaaaa agatgaaaat gtgttttatg tttggaatca ctatttttca
    37501 aaagaaagtt tcttattaga agttgaaaat attggattta agtctgttga gttttttagt
    37561 aatattaagg gtgaagcata ttctgacgat agtatgacta tgggattagt tttacaaaaa
    37621 taataatttt tttaaaatga ataaataaaa acttgaaacc tttaacaata aaataacata
    37681 ataaaagctt acatattgaa aaatggaaac ttttatgtta tttttagtac attacaaatt
    37741 tgcttatata aaaatcaata cttgaattat tatttttatg tgaaatttat ctatagtata
    37801 tttttataaa caagtaatgt tattaaaatt aagtatatag ttaaaagtgt atagcaaaaa
    37861 ggctgttata ttaatgttag aggttcaggg aaaatatata aagcaaagta tttacagata
    37921 atgtagattg cacagctata agttagataa tagaattatg taatcaagaa tttacaacaa
    37981 agtataagat aaggataatg ctaaattgcc atacaggtgc tagatgtgta aatggattta
    38041 attaatacta ttgataaagt gcaacaagca cataaaccaa ttgatgagat tattaaaact
    38101 ataagagata tagttgacat aattaaaata ttggaaccta tttataattt taaatcaaat
    38161 caataatgat taagattaaa ataatattaa ggcatcaatg ttataagagt acaatataag
    38221 gagtactata tactactcct tacttataca tattaggcaa taggaaattt tttcatagtt
    38281 aaattttcaa atatttttta gggaacttta taattgagaa ttaagggtat agtatgtgat
    38341 gaacttacta aatttataat taggttatat aatggaataa tcatcaatag ttttacttta
    38401 gggaaaatat atgcttaagg aagtatagct tactaatatt attaaaatgt atatttaaaa
    38461 tgataaaaaa agaattagac aagtatttag taatttgatt atgcaaaatt ctatcaatca
    38521 ggaaccctat gactttagtt atgggaggtt cagtaggtaa cttgttgaat gaagtttata
    38581 ttatttaaat aaactactta attcagataa tataaaaagt cagaatttta agaatagagc
    38641 tatataatct tagctattag gagaattact atgataggaa tatattttag tggaacagga
    38701 aattcaagat actgtgtaga aaaattttta caagaatatg atataacagc aaattcttat
    38761 tctattgaag ataatgaact tttacagcac atcaataatc atgagaatat tatttttagt
    38821 tatccggtgc aatatagtaa tgtgccaaaa atattgaaag attttataat aaatcattca
    38881 actttgtgga atggtaaacg tgtttttatt attgcaacta tggctctatt tagtggagat
    38941 ggctctggtg tgttagctag aatattaaaa aaatacggtg ctataactgt tggtggatta
    39001 catgtgaaga tgccagatag tataggagat gaaaaggtat taaaacattc tttagagtat
    39061 aatagaaagc ttgtaataaa agcagaaaag aaagtaacta aggctgctaa aaaactgaaa
    39121 catgggtcac caccaaaaga agggttgggt tttttgagtc atattgtagg gttatttgga
    39181 caacgattgt attttatcaa taaaacaaat atgtatacag ataaactaaa aattaatact
    39241 gagaaatgta ttgtatgtgg taaatgtgtt aatttatgtc caatgaagaa tctagtaatt
    39301 aaaaattgta tgattgttgc aaatgggcaa tgtacaatgt gttatcgttg tgtaaataat
    39361 tgtgccaaaa aagcaattac attgttaggt aaaaaagttg ttgaacagag taatattaaa
    39421 aaatatatgt aagaaattta aagttttatt gaatgtaaat tgatgtatat tttatgttag
    39481 aaagagaggt taaataatgg aatactacat agttgattca tttgcaacta aactatttaa
    39541 aggaaatcct gctggagttt gtgttcttga cagaagaata cctttagagt taatgcagaa
    39601 aatagcagaa gaaaacaatt taccagaaac agcatttgta gttaaaggta aaggaaatta
    39661 tgaattacga tggtttactc ctaaagcaga aattgattta tgtggtcatg caactttagc
    39721 agcagcttat gtaatatcaa attttattga tgttaatgta aaaaagatag atttctttac
    39781 tcaaagtgga aagcttgaag ttacacgaaa tggaaatcta tatgaaatga tatttccaga
    39841 aataatgcct attgaaatag agttatcacc gcaacaagct aatttgatag gctgtgtacc
    39901 aagtgctgtt tattcttcaa gagatttaat cttattgcta aacagtgaac aagaagttat
    39961 aaattataaa cctaattacg cacaattgcg taaattgaca gactggttag gtataataat
    40021 cacagcacaa ggaagtaata cagattttgt atcaagatat ttttgtccag aattagattc
    40081 agaagaccct gttactggtt catcacattg taatcttatt ccatactggt ctgaaaagtt
    40141 gggaaaacac aaaatggtag ctgctcaact ttctaatcgt ggtggtataa ttcagtgtga
    40201 agtgttgaag gataatactg tgaaaatttc tggtgaagca gtcttgttta tgcagggaac
    40261 aataaagatt gatatttaaa taagtataat aactaattta ttatgaaaaa taattaattt
    40321 tcttagtgtt aacaataata aagtagagtt aaaaaacttg atttcactta aatcaatatg
    40381 atagatgttg atactaagat tgacaagcat gattaaaaaa gataatattt aatctataaa
    40441 gataaaaaca cagtctggtt ggtagtccag acgcagcaat ggctgtcagt aacctgcctc
    40501 cttggttgtc cgttctttag aaagtaattt aaggaggaac tagcaatgga caaaattagt
    40561 ggaaaattaa cagtcttatt tgaagaacca ttttgggtag gtatatttga aagacaagat
    40621 ggtaaaaaat atgaagcatg tagggtagtt tttggagcag aacctaaaga agtagaagtg
    40681 tatgaattta tacttgaaag atttttctca ttagattttg gtagcattaa attagaaaaa
    40741 aatgtgacca aagacaacat tggatacaaa agaatgcaga gaaaagtaaa aaaggaacaa
    40801 gaaaaagaaa ctatagggac taaggctcaa aatgctctta agcttcaata tgaagaaaga
    40861 aaacaggata gaaaaaacct agctaaaaat agaaaagaag aagaaaaaga aagactattt
    40921 aatttgaaac aagaaaagag aaaagctaaa cataagggtc attaatttta attaaatatc
    40981 tttttaataa ttgctagaaa aaggtgtata aaatttttaa ttttatacac cttaatttat
    41041 tgaaaagaat aaggttttat atttcaatta ctttaaaata taaaaatata ctaataaaaa
    41101 ttgtaaaaat agtataaatg gtataccaaa tgtaaattta atgtgtttag ttttatgtct
    41161 aaaagaatac attccaatta tagaacctat actacctcca attactgcta tagacataag
    41221 agtagcttct tttattctcc attcgtttct aattgctctt ttcttatcta tgtacattga
    41281 aaagaaagca atagaattaa tcactataaa atatattaga ataaaatttt tcacagtctt
    41341 gcctccataa aaatatatta tacattataa aacaagatat ttgttttgga aagttaaatt
    41401 tgtaattagt acatataaaa tatttgataa gaataaatat aatattaatt ggaaaattta
    41461 aaaaaattaa acaattagca aatagggggt atatttataa gacacaaagt gataaaatct
    41521 atttagaaaa taatgtaaaa taacaggagg ataaagcaaa atgaaattta tagtagaaaa
    41581 agaagttttt gataaattag aaaatgtatg ctttggtgta gtagttgcaa aaggaataga
    41641 taatactaaa gaaatagaaa gaataagcaa ccttttagat ataagtatag atagagtaga
    41701 agattacttc aaagataaaa aagtaaagga atcagaagaa attataccat atagagaggc
    41761 atttagaagt ctaggcatga acccaaataa atttatgagt tcaatagaag caatgacaac
    41821 aagggttgct aagaataaga aacttcctca tataaatcct attgtagatt taggaaactc
    41881 tatttcttta aaatatttac ttccaatggg tgctcatgat atggatttta gaaatgatga
    41941 tgtatatgtt agattttcta aaaaagggga taaatttgta ccatttggag aaactgatgt
    42001 tgaattaatg gaagaaggag aattaattta ttcagttgga gacatggtaa aaactagaag
    42061 atggatatgg agacaaggag aggaaggaaa aattactaat agctcaaaaa atatattttt
    42121 tcctatagat ggttttactg atgctaattt agataaggta atgagtgcaa gagaagaatt
    42181 agcaaaattg ttaaaggaaa tatttaattg tgaaattaaa gtaggttttg tagataaaga
    42241 taatcctgaa atggaaatat aataagttgt tgaatacttg ttaagatatt atatttactt
    42301 aatgatgtta aaaaggtatt aaaaaagaaa ggtcgtagta aatttgaaaa aaactataat
    42361 aaagaatgta aatccaatga ttgaaaataa gtttatagga ctttttgaaa tagagtataa
    42421 aaacaaatta gatgaagata aggtttggat ggtagcatca agaaaaagta gtgagcaatt
    42481 aaaaaatatt tatttgaaga atgaagaaga tagtgtagat gcagttgtaa tagttgggct
    42541 tcataaaagt agtaaaaaat taattttaat aagacaattt agagtaccta ttaatggata
    42601 tatatacgag ttaccagcag gtcttgttga tgaaggagag tctatagata tttctgttga
    42661 aagagaactt agagaagaaa caggacttac tcttttagaa attaaaaaaa ataaaagtat
    42721 tgataaagtt tatttatctc ctggaatgag tgatgaatct gttgcctttg tttattgtat
    42781 atgtgatggt gatataacag atgaattttt agaaccagat gaagagattg aagcgctttt
    42841 aatttcgcaa gaagatgcaa aagagatttt acaaagtaat cataagatag acacaaaagc
    42901 atttttgatt ttacaaatgt ttgtgagttt aggagctaaa ttatttgaat agatatatag
    42961 aaaagaggtt atatagaaga gtaaaataat aaagtttatt ttacttgtat aaattataat
    43021 ctcttttttt atacaataaa gtataatttt gtgtattttt aaataagtga cttgactctt
    43081 aaattttcat aatatgttat aaaccaattt aagatactac aataattaaa attccaaaat
    43141 tatttaacat atttgcaatt aaaatgagaa aaggtaaagg ctgaatgatt gaaaaatttg
    43201 atgtaaaata gtagattagt ttaatactat agtttgtagg gttaaaaatt agaaattgta
    43261 agggagataa attctatgaa aaaattagtt attattttaa ttagtatcat tagtgtggtt
    43321 agcttgacag cttgtaaaaa aagcaatgaa agtaaatata ataatttaaa caacaaagaa
    43381 tcaggacaaa caaccattga aatggactta gataaaaatt atgatacttc agacccattt
    43441 gttaatgcac gtttgttttg tgtgtctaat gatatagatg ttttagacac agagatttct
    43501 tttaaaatgg atggagatag tggtattgtg gaaataaagg acaataaaac agatgaaact
    43561 ttatggagta atatatggca tggaagcgtt gataatgata cattcgcaat ttctctttct
    43621 aatatacaaa aagagaaaga gtatgctata tgctttactg gaattaaaat aaatcatgca
    43681 gttgtaaagg ttacttttga aagcaattta gttaaggaga aagaaaaacc ctcaaaataa
    43741 attccagatt gtctataact tgatattcag tacataaaag cagttgatat ttatgattga
    43801 ctgctttttc ttatcaaaaa ggataggttg tgcattttta cttgaaatag tttatgcaca
    43861 tcaaaagttg gtgagcatga tattggaaat ggtaagcatg aaatcttgat aagacaagga
    43921 aataaattta agttttcaat taagtatatt tccataattt agttaataat aagctaatta
    43981 ttatttatat tttgatatat aaataataat tgta
//
LOCUS       DAEPUT010000029        43451 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.029, whole genome shotgun sequence.
ACCESSION   DAEPUT010000029 DAEPUT010000000
VERSION     DAEPUT010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43451
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.029"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            240..1334
                     /locus_tag="KRL22_001699"
     CDS             240..1334
                     /locus_tag="KRL22_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272195.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDRLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPIIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDNHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            1559..1975
                     /locus_tag="KRL22_001700"
     CDS             1559..1975
                     /locus_tag="KRL22_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272196.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(2157..2726)
                     /locus_tag="KRL22_001701"
     CDS             complement(2157..2726)
                     /locus_tag="KRL22_001701"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBH1272197.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGEYGIR
                     EPNEKSPTVDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            2880..4037
                     /locus_tag="KRL22_001702"
     CDS             2880..4037
                     /locus_tag="KRL22_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HBH1272198.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGASKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            4641..5123
                     /locus_tag="KRL22_001703"
     CDS             4641..5123
                     /locus_tag="KRL22_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1272199.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIYINEF
                     "
     gene            complement(5822..6976)
                     /gene="nagA"
                     /locus_tag="KRL22_001704"
     CDS             complement(5822..6976)
                     /gene="nagA"
                     /locus_tag="KRL22_001704"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH1272200.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKM
                     ATYVPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK"
     gene            complement(7059..7784)
                     /locus_tag="KRL22_001705"
     CDS             complement(7059..7784)
                     /locus_tag="KRL22_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1272201.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            8051..8980
                     /gene="pfkB"
                     /locus_tag="KRL22_001706"
     CDS             8051..8980
                     /gene="pfkB"
                     /locus_tag="KRL22_001706"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH1272202.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGMNIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLVEIDKYQDLVEVKKLS"
     gene            complement(9109..10026)
                     /locus_tag="KRL22_001707"
     CDS             complement(9109..10026)
                     /locus_tag="KRL22_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH1272203.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVKFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            10497..11666
                     /locus_tag="KRL22_001708"
     CDS             10497..11666
                     /locus_tag="KRL22_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1272204.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            11715..12566
                     /locus_tag="KRL22_001709"
     CDS             11715..12566
                     /locus_tag="KRL22_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH1272205.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            12892..14793
                     /locus_tag="KRL22_001710"
     CDS             12892..14793
                     /locus_tag="KRL22_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1272206.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVAGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            14796..15839
                     /gene="ypdE"
                     /locus_tag="KRL22_001711"
     CDS             14796..15839
                     /gene="ypdE"
                     /locus_tag="KRL22_001711"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH1272207.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            15854..16159
                     /locus_tag="KRL22_001712"
     CDS             15854..16159
                     /locus_tag="KRL22_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1272208.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            16256..16591
                     /locus_tag="KRL22_001713"
     CDS             16256..16591
                     /locus_tag="KRL22_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1272209.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            16623..17945
                     /locus_tag="KRL22_001714"
     CDS             16623..17945
                     /locus_tag="KRL22_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1272210.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETITHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            17955..19025
                     /locus_tag="KRL22_001715"
     CDS             17955..19025
                     /locus_tag="KRL22_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1272211.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGKYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            19030..20217
                     /locus_tag="KRL22_001716"
     CDS             19030..20217
                     /locus_tag="KRL22_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1272212.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKDFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(20414..21286)
                     /locus_tag="KRL22_001717"
     CDS             complement(20414..21286)
                     /locus_tag="KRL22_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBH1272213.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(21680..21871)
                     /locus_tag="KRL22_001718"
     CDS             complement(21680..21871)
                     /locus_tag="KRL22_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272214.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            22091..23137
                     /gene="cobT"
                     /locus_tag="KRL22_001719"
     CDS             22091..23137
                     /gene="cobT"
                     /locus_tag="KRL22_001719"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBH1272215.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            23169..23729
                     /gene="cobU"
                     /locus_tag="KRL22_001720"
     CDS             23169..23729
                     /gene="cobU"
                     /locus_tag="KRL22_001720"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBH1272216.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            23739..24512
                     /gene="cobS"
                     /locus_tag="KRL22_001721"
     CDS             23739..24512
                     /gene="cobS"
                     /locus_tag="KRL22_001721"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBH1272217.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            24532..25146
                     /locus_tag="KRL22_001722"
     CDS             24532..25146
                     /locus_tag="KRL22_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH1272218.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      25213..25392
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            25521..27020
                     /locus_tag="KRL22_001723"
     CDS             25521..27020
                     /locus_tag="KRL22_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HBH1272219.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            27059..28435
                     /locus_tag="KRL22_001724"
     CDS             27059..28435
                     /locus_tag="KRL22_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HBH1272220.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            28436..29407
                     /locus_tag="KRL22_001725"
     CDS             28436..29407
                     /locus_tag="KRL22_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH1272221.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYVIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            29439..30509
                     /locus_tag="KRL22_001726"
     CDS             29439..30509
                     /locus_tag="KRL22_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1272222.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            30511..31398
                     /locus_tag="KRL22_001727"
     CDS             30511..31398
                     /locus_tag="KRL22_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH1272223.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNHLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKSMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            31386..32018
                     /locus_tag="KRL22_001728"
     CDS             31386..32018
                     /locus_tag="KRL22_001728"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HBH1272224.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            32027..33253
                     /locus_tag="KRL22_001729"
     CDS             32027..33253
                     /locus_tag="KRL22_001729"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HBH1272225.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDDGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNIDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            33250..33858
                     /locus_tag="KRL22_001730"
     CDS             33250..33858
                     /locus_tag="KRL22_001730"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HBH1272226.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            33848..34423
                     /locus_tag="KRL22_001731"
     CDS             33848..34423
                     /locus_tag="KRL22_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HBH1272227.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            34416..35168
                     /locus_tag="KRL22_001732"
     CDS             34416..35168
                     /locus_tag="KRL22_001732"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HBH1272228.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            35152..36273
                     /gene="cbiG"
                     /locus_tag="KRL22_001733"
     CDS             35152..36273
                     /gene="cbiG"
                     /locus_tag="KRL22_001733"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HBH1272229.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            36270..36995
                     /gene="cobJ"
                     /locus_tag="KRL22_001734"
     CDS             36270..36995
                     /gene="cobJ"
                     /locus_tag="KRL22_001734"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HBH1272230.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     GKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            36992..37744
                     /gene="cobK"
                     /locus_tag="KRL22_001735"
     CDS             36992..37744
                     /gene="cobK"
                     /locus_tag="KRL22_001735"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HBH1272231.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEINYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            37763..39241
                     /locus_tag="KRL22_001736"
     CDS             37763..39241
                     /locus_tag="KRL22_001736"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HBH1272232.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIGDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            39271..40176
                     /gene="hemC"
                     /locus_tag="KRL22_001737"
     CDS             39271..40176
                     /gene="hemC"
                     /locus_tag="KRL22_001737"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBH1272233.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            40166..41665
                     /gene="cobA"
                     /locus_tag="KRL22_001738"
     CDS             40166..41665
                     /gene="cobA"
                     /locus_tag="KRL22_001738"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBH1272234.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            41682..42647
                     /gene="hemB"
                     /locus_tag="KRL22_001739"
     CDS             41682..42647
                     /gene="hemB"
                     /locus_tag="KRL22_001739"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBH1272235.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            42800..43378
                     /locus_tag="KRL22_001740"
     CDS             42800..43378
                     /locus_tag="KRL22_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HBH1272236.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCRAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        17230 a         4572 c         7624 g        14025 t
ORIGIN      
        1 tatgactaat atataattta tagagaaatt aattttatat ataatgacta cttagataaa
       61 ataatctaaa aaaattatga aaggaggact agggtataaa attagattat aagttttaag
      121 ttattatact aaaaagctat aaaacagtta tcatgtattt tatgttaaag gaaattgtag
      181 gtagtttatc gaattgttta agcagaagaa aaaatttcac atggggaggt aactgagata
      241 tgtcagaaaa agtaaatgtt aaaacagtca tcagtttcgc aggtgcgtat gtagcaacag
      301 taatcggttc tggatttgca acaggacagg aaataatgca attcttctct ttttatggtt
      361 ttgcaggtat tattggtggg ataatttcaa tggtattatt ctcatggatg ggtgcttcag
      421 ttatgtcaaa aggtaaagag cttcaactta aagaacctat caaaatttat cgtgtttatt
      481 gtggtaagta tttaggaata ttctttgaat ggtttggacc tttattctta tttggtgttt
      541 tcgtagtaat gatttcagga gcaggagcaa ctttaactga atactatgga ttaaatccat
      601 ttgtaggtag agtaggtatg gcagtagtag cattattaac tgtttcatta ggtcttgata
      661 gattatcaaa gatactaggt ggaataggac ctataataat aatatttaca cttttagttg
      721 gtggtataag tttagctaaa aatataggta atataggaga agctgcacaa gttcttagca
      781 ctgtaaagat agctaaacca gttccaaatg cctatctatc tggtgtaata tatactactt
      841 ataacacaat tgttgttatg gcattcttaa ctggattagg agcaagtgct gctaacaaaa
      901 aagaagctat ttgtggtggt atattaggtg gagtagcact tatggctgca gctataatga
      961 tgcacttagc tattctttct gatataggaa acttatattc aaaagcaata ccatcattat
     1021 tcttagcaga taagatttca ccaataattg gagttttatt ctcaataatt cttatattag
     1081 gtatatatac aacagctgta cctttattat ggtcagtaac taatagattt gtagatgata
     1141 atcatcctaa gtttaaatta ataactttaa tagcagctat attaggtctt ataggtggat
     1201 tcctaccatt tgataagctg gttggtattt tatatccata tactggatat atgggcgtca
     1261 taatactggt ttgtgttctt tatagacaga ttacaaaaac atctggatat caagaaggaa
     1321 tcagtgacaa ataaatattt tttaatattg taaactcaag agctatatga aaacaatgaa
     1381 aatgttttta tatagctctt tttattttta gcttgtttat tatgaaatag aaaaaacatg
     1441 ttttttagtt acattacata tatttataat tatgtataaa tatatactaa tcaataattt
     1501 agagtctaag ataagtttat aaatcatata tttagaatat atgggaggag tgataagatt
     1561 gaatgtaaag tttaatatta aagggataat ttatggagtt atagctcttg tattcgttat
     1621 agggggattt atattcatac caagtatgtt tgtagagaaa tctaaaccca tagattatac
     1681 agtattacaa agaaattcaa taccagaaaa gatactagat gtgatggata agtatacaaa
     1741 tgaagaaaga gcattagcgg ctaaaatcga taacaaaata tacattatag tgactagagg
     1801 aaataataaa tatggtatag aaatggacaa aatagaaagt gtggttgaag aaggaaagga
     1861 tgttttgagg gtcaagataa agtataaaga taaggaagat tcttttccat acatagttgt
     1921 tgaaacaaat atgagtgaac ttccagatag aatagaatta aatgcaacga aataagaagg
     1981 tattttataa ttaaataact gcatattgta caataaagtc atggttttta ttaatgtaag
     2041 taaattgtat atggttctta ttgttgtaaa agccatgact taaaatgctt ataaagtaag
     2101 atattaacag tagtatttat tactacatta aatggggtct ggaaatactt aatattctaa
     2161 ctatttggag tgataattct agtttcagta actatgtagt ctaattgtgc atcatgagtt
     2221 tcttttggaa tagaatcgaa tatctggaag tcaaatgcta tgccgatagt aatagcatct
     2281 tttcttaagt tttctaaaaa tctatcataa aatcctccac catatcctaa tctatagcaa
     2341 tgtatatcat atgctacagc tggtacaatt acaacatcta aggccttaat atcaactgta
     2401 ggtgattttt cgttaggttc tcttattcca tattctccaa ttctcaatcc ctcttttaaa
     2461 tctgttattt gagtagggat taatgtatga ttttctttta ttgtgatggg acttgatact
     2521 attttcttta gagacaaaag ttttttgatt aaattatctg tttgaacttc attgttaaaa
     2581 tttagataaa gcattatatt agttgcattt cttatatctt ccatttgaag taatttttca
     2641 gtgattaaat ttgaattact aagtacgaag tttgcactct tattttttct tgattcaata
     2701 actttttttc taaattcttt tttcataaaa taattcctcc cttaatatgt tataatgtgt
     2761 acagcaattg tatttaatat aaattttagt ataatttatt gtaataaagc aatatatttg
     2821 ggtaaatgta ataaaaataa cagctagtca tataataata atagtttatg taaaaggaga
     2881 tgtatcttgt gatttcaaag aagaaagcta tttttttagg ggtgatttta gtaattataa
     2941 cagctatggt tacatcagca tttcagttga cattggggaa taaagttgta atatcgaaag
     3001 aactctatga agactataaa aaatatgata agttgttagg actagaatct atcataaaac
     3061 aagattttta taaaaaagta tcagatactg atttggtaaa tggagcatca aaaggtctat
     3121 ttctaggaac aaatgataag tattctggtt attatactaa agatgaaatg gagaatctaa
     3181 ttaatgatag tgaaggttct tatgttggtg taggtatgta tataggggca tcaaaagatg
     3241 gtggcttagt agtagttccc atgaaagatt ctccagcaga gaaagcaggt gtaaaatcag
     3301 gggataaatt agtaaaagtc aatggaaaat ctgtctcata taaaaattca gatgaagctg
     3361 ttcgtatgat gaagggtaaa aaaggtaaaa cagttgaact gactatatta agagaagata
     3421 aacaattgaa ctttaaagta aaaacagacc agataattga gaagagtata gaaagtaaag
     3481 taattgataa tgatttagga tatatagaaa ttacccaatt tatatcaagt acatatactg
     3541 actttgataa agctttaaaa gaattaaaag caaaaaatat caagggatta gtaatagacc
     3601 ttagaaataa tcctggtgga atgctagata tatgtaaaga agttgctgat gagttaattg
     3661 gtgaaggaac tatagtatat acaaaagata ataagggaaa tactgagtac ttgaaatctg
     3721 ataaagaaaa attgggactt ccaatagtag tgttaactaa tggagaaagt gcttctgctg
     3781 ctgaaatatt aacagctgca atcgttgata ataaagaagg tatttctgta gggactacaa
     3841 cttttggtaa agggttggta caatcagttg taagattgaa ggatggaaca ggatacaagc
     3901 taactactgc tcaatatttt acacctaatg gagattatat caatgaaaaa ggtataaagc
     3961 ctactattga agagaaagat gaaaataaac agttagatgt agcaactaag tggcttagag
     4021 aacagattga taaataggat ttaattttta taaacttata ctataaaata aagaacatta
     4081 taagagagat gtctcaaaat gaacttttta gttcatgagg gagtctggaa atatttatgt
     4141 gtattcttta aataaaaatt tattttttaa gtgataatta aatttttaca gacagggcta
     4201 tggttttaaa aatcatagcc ttattttgat attttttaaa aacacattgc aacccagttg
     4261 ttccaaatat tatatcattt acttttaaaa tatcgcaaac tgcatattat atattcatta
     4321 taatataatt tatctaacta gaaccttagt ttactaatta aattagatgc atagaataac
     4381 ttttttaaac attgaaaata aattaaactc taaacacatt taaatataaa tttatatatc
     4441 attttgactt ggttaaacaa tttcatactt atcgatataa aaataggtta taatataaat
     4501 gttcattatc ttataaccta ttttatataa tttattccta aaacatgtga atgtttttta
     4561 tgatagtttg aagaaattat aaaatcactt tataattgaa tattatatat aaattaattt
     4621 aaatatagaa aggaaaatat atgtacaaca atatcaaaaa tattttaaaa gaaaatcata
     4681 taacgtttga agaatatgac catgaaccta ttttatcatt tgaaaaagct aaagaaataa
     4741 gagaaaaatt acaatatact ggagtagaaa gtaaaagttt atttataaaa gataggtctg
     4801 gaaattacta tatatttgta accacagaag gaaaaaaatt agatccaaaa actataaaaa
     4861 atgttttagg tggaaaagta tctatatgtt caaaagaaga attaacacaa aaaacacaat
     4921 gtttgcctgg atgtgtatct ccttttggat atgagaaaaa tatctctctt gtaatagatc
     4981 aagatatatt taaccatgat aaaataatct tttcaccagg gataccagaa aagacattta
     5041 ttattacagc tagtggattt aaaaaagtaa taaacaatat aaacaataca acttataaat
     5101 atatatatat taatgaattt taatcataat tgtaaattag agaaaataac attagaaatc
     5161 atgcttaact atagtgtaaa taaattatat tcaacacaaa agattgatac tattattaca
     5221 atagttactg ttaagctcaa attcaatgta ttatgagtta ttatttttaa attttaatta
     5281 caaaagcagg gtagttttaa ctactctgct ttatatttaa cataaaatat ataaaatcaa
     5341 caaaatgatt ttagtctatc tattagatat tcttcgctct caatgcttag aacttttaga
     5401 tatatacaat aagtgctttc atttgtaaaa atttctatag tattatcttg tttatttaca
     5461 cctacaatat ctttaaaatt gatatgattt ttagtatttt tacatttgaa aatatatctg
     5521 ttatcaatta aaatctcatc attagtaatt gaaatatagg gtttatctca tgctttatta
     5581 aaaatttata tgtttgttca agataaaaac ttacaaataa taatagaaaa gttactttaa
     5641 atgtacatat tatcgaaaat attatcacaa aaatacttat aatatatatt tgtttaaaat
     5701 aacctctatc gcaatagttt attaacgata tggaaataaa agtgttaaat cagattttgg
     5761 agaaataact ttaaatattt ccagactctt tttagacagc ctccataacc ttatattgaa
     5821 cctatttatt aactttgtac ttacagatac catttatata agtttcgtgt atattaaagt
     5881 cattatctgt tactataaag tctgcatcca taccttgata tatagagcca cagacattat
     5941 caatattaca acttaaagca gggacatatg tagccatttt tattgcatct tctaaagttg
     6001 atatgttcca atcaactata tttctcacag ccttgtccat agttaataca cttccagcta
     6061 aactcccact atttaatctt gcaacactat tttttacatt tacattaaac ttaccaagag
     6121 tatattttcc atcctccata gcaccagctc tcatacaatc tgtaattaaa gctatgttat
     6181 tactagactt agcatccatc attattttaa cagctattgg gcttacatga tgaccatcac
     6241 aaattaattc agcataagta tcttttagta ccatagcagc cccaaccatt ccaggttctc
     6301 tatgatttaa aggactcatc ccattatatg tatgtacaaa cactttagca cctgaattaa
     6361 cgacttgttt aacttgctca aatgtagctg aactatgacc aagagaaact gatatattat
     6421 ttttagttgc atatcttgtt aattctattg aacctttacg ttctggagca attgctattt
     6481 ttcttattaa atttttcgat tttttttgcc ataattttaa tatattgatg tcagggtctt
     6541 taaaatattt ttcattttga gcgcccttat atttttctgt aaaaaatgga ccttctaaat
     6601 aaataccttg tatttttgca ccctcaactc gattgaagct attgcttata ttttctacag
     6661 aatcacttag tgtatctaca gaatcagtta aagttgtagg taggaaagat gttactccat
     6721 attttaataa gccttttgaa attgtgttta ttgcttcaaa tgtattgtcc atgacatctg
     6781 cacctaaaag accgtgaatg tgagtatcaa ctaagccagg agcaatatat ttacctgaaa
     6841 aatctataac attatcagta atattaggtc tttcttgttg aaattcaccg aatttgccat
     6901 taattatact aaggtaacct ttttctttga ttccatgttt cataaaaaat ttatctgcat
     6961 aaataaaact tttcaaaata acctccttat aattatacta tcattgtggc attgacgctt
     7021 ataatatcat tctgttttct tgaaagttat ttaacttact atcttacatg tcttactcta
     7081 tatacaaatt tatcacttct agcgacactc aaagtaaatt caataactat attgtcatca
     7141 ttatatgtgg tacgaagtaa tttcagacaa ggtgaatctc ctggtacttc caataactta
     7201 gcttccttat cagagattat tccagctgaa aattcttcat cagcaacttt aataatctcg
     7261 ccataatctt ctctaaatat ttcatataaa ggtttttgtt cgattttttc ttttgtcaat
     7321 cctataaatt ctttcatagg aagatatgtt ctttcaagca tcataggaag gtcatcagca
     7381 agtcttaaac gcattatttt tatcattttt tcaccaggag ttatacctaa tttttcagag
     7441 aaatactttg tactttctac tacctcaaat gataatacct ttgtacctgg cttttttcct
     7501 tgtgttctca tataatctgt aaagctataa ctttccatta agttttgaga attttgactt
     7561 agtgcagcaa caaaagttcc ttttccatgt cttttatata tatatcccat atgctctaac
     7621 tcagccatag ctagtctaac tgtggttcta cttactccat attcatcaca aatttttctt
     7681 tcggaaagca ttctatcgtt tggttccatc tcattttcaa tcttagttct taatatctca
     7741 acaagctggt catatattgg tcttttatca tttcttttta tcataaaaat atagtccttt
     7801 ctaagtggtt attaccacaa tttgattata gaatatagaa ttatttatgt caatgaataa
     7861 agtttaatca aaattcaata agtaaggcta ttaatttatt ataaaattat ggtacattga
     7921 caaaacaagt aaaataattt atattcaaat tggtaataac cactttggat atattatatg
     7981 aggtattttt tattttacag attaatttat tgtttagaaa agtaaaaatt aataatgagg
     8041 agaatctagt atgattacag taataacatt caacccatct atagatagaa tgtatagagt
     8101 gaataatata aacataggtg aggtgcaaag ggtagtaagt aagaatgcaa ctgctggagg
     8161 taaaggatta aacgtagcta aggtatgtaa aattttaaaa gaaaatcctt tagctatggg
     8221 atttctaggc ggatttaatg gagaatttat aaaaaatgaa cttagaaaac tagatataca
     8281 aaataaattt acaaaaatag agcaggaaac tagaaattgc ttaaacataa ttgaggacaa
     8341 taaagttagt acagaatttt tagaaaaagg accaatagta gaaaaaagcg atttagagag
     8401 atttgaaaat gatatagagg aagtactaaa aaatactaaa atactggtag cttctggtag
     8461 ttattgtgag aatatgccga tagactatta tgaaaagata ggaaatatat gtagagcaaa
     8521 taatataaag tttatattag atacatcagg agaagcatta aaaatagctt taaaatcaaa
     8581 accatattta ataaagccaa atatagatga aataagacat ttattaggaa tgaatataga
     8641 atcaagagaa gaaattatct tgtcaggaaa aaaacttatt gaaatgggtg cagagaatgt
     8701 atgtatatct ttaggaaaag atggtatggt gtatttaaac gaagataatg tatatgatgt
     8761 aaaagtacca gttgtaaagt gtataaatac tgtaggtagt ggagatagca cagtggctgg
     8821 atttagtgta ggtattttaa ggggttataa aatagaaaat ttacttaaat ttgcaaatgc
     8881 ttgtggtata agtaatgctt taaatatgga aactggattt gtagatttgg tagaaattga
     8941 taaatatcaa gatttagttg aagtaaaaaa gttaagttaa atacatttaa tgggaatata
     9001 ataaatttaa tgttgttgta atagatttta attttaatat aaaagatata gtcttatata
     9061 aaaataggtt agaaaaattc atttttaacc tatttttata ataaatatct attttactga
     9121 atttataatt ttctctagta atctttgagc cttgatacac tcttctccat taatagctgg
     9181 ttttatatta ttttctatac aatcaataaa atgatttgat atatcctcaa aacccttttg
     9241 ttttaatatg tttacccatg caccactttg ctttaaagtt aggtttccac cttcttctat
     9301 ttccagtaca ttaagattct taactctttg aatcttaccc tttgaaagaa tttcaacttg
     9361 ttctaacttt gttccagaat ctctatgcat agaggtgttt atagagaaat ttttaccttt
     9421 aagtttatga cttacaaata taagattctt attgtctgtt aaaaataaat cctctccact
     9481 aatttcaaca tcttcatttg ctaaccataa agcagtgtca ataacatgta tatagtcatc
     9541 tataagagta ctgtcgaatt taacatttct taaggaattt aatccatgtt tacatatatt
     9601 gatagataca atttctgtag cattattttt aatttctttg tacataggac agaatctacg
     9661 gttgaatcca accattaaat ttaagttttt tttcgtactt aattcgataa gttcttctcc
     9721 ttgacttact gttgaagcaa gaggtttgtc tacatataca tgaacaccta aatttaataa
     9781 tatttttata atttcgtagt gtgtttctgt agagctatgt agaaaaatac aatcacattt
     9841 tttagctagg gattcaatag aatcgaatgg catgattcta taatcactac agactttttc
     9901 ccttttaact ttatttggag taaaagctcc tacaaactca aatctctcag acttagttaa
     9961 tataggtaaa tatgcctttt gagctatgga gccaagacct atcattccca tttttatatt
    10021 tttcataata ctttctccta aggtttttat atttacagaa ttgattataa ttcagacaca
    10081 taaatttgta aactttgtat caaaaaataa atttaaagct tatataagta aattagcgaa
    10141 ataagaaata ttgataaagt aattttgtag gatatccata aaattgattg atataaatat
    10201 tttatgtatt gacaaaaaat tcaaattaat ttatatttgg attagtggta attaccactt
    10261 tggtctgaac aagtttttat cgtaaaataa aaatactaaa gtatatagag tatgatttta
    10321 ttaaattttt aaagataaac tataaaatta attaaaatct atagtgtata ttttatagtg
    10381 agtttaagta gtactaaaaa atctaagcaa aaaattataa aagagtatat ttttttatag
    10441 tttaaagtgg ttataacctc attaccaaat gtaaacgtta caagtatgaa aggagaatga
    10501 aaatgtttaa attagaagaa caaaaactaa aagatttagg tgcaataata acaactaatg
    10561 aaataaaaca acagcctgaa ttatggttag aaacttatga aatatataaa tctaacaaag
    10621 aaaaattaag tagattcata gatacaataa gtaataatca tgggcagttt agagttatat
    10681 ttacaggtgc tggaacttca gcttacatag gaaattcaat acttccttac cttaaaaata
    10741 aaaatgacat aagaaaatac atatttgaag caatacctac tacggatata gtttcaaacc
    10801 catatgacta cttaaaaaaa gatataccaa cattattaat ttcatttgca agaagtggaa
    10861 atagtcctga aagtttggct gctttaaatt taggaaataa gattgtagat aatttttatc
    10921 atttagctat aacttgtaat ccagaaggag aactggctaa gatgactaaa aacgacgaaa
    10981 ataattactt gttattaatg ccatcaaaat caaatgatga aggctttgcc atgacaggaa
    11041 gtttttcgtg tatgatgtta tctgctatgt taatattcga tagtttagaa gatgatgtag
    11101 aaaagtcata tataaatgca ataattgaaa tgggaagaaa tgttatagat agaaaagatg
    11161 aaatacatga gttaataaat aaagattttg atagagttgt atatttaggt tcaggaggat
    11221 taggtggttt gacacaagaa gcacaactaa aacttttaga acttacagca ggaaaaatat
    11281 ctacagtgta tgattctcct atggggttta gacacggacc aaaatcattt attgatgaaa
    11341 atacacttgt atttgaattt gtatctaact gtttatatac aagaaaatat gatttagatg
    11401 ttttagagga gataaaaagg gataaaattg ctaaattcac ttgtgcagtg tcagtagaaa
    11461 atgaaaataa cttctcagga acaaagtttg agtttaaaga aaagtataat aaattaccag
    11521 atgtgtatct tgcaatgcca tacatattgt ttgcacaaac tatagcattg tttgtatcgg
    11581 taaaggttgg aaataagcca gatactccat cagctacagg aacagtaaat cgagtagtaa
    11641 aaggtgtaac aatatatgaa tattaaaaga taagattaaa atattataac taaataattt
    11701 gggagggtat caatgtggca ttagtaacaa caacatcaat gcttaaaaag gcacaagatg
    11761 aagggtatgc agtaggagca tttaatgtag aaaatatgga aatggtaatt gctgttatag
    11821 aagctgctga ggagttaaat tctccagtaa tattacaaac tactccatct actgtaaaat
    11881 atgcaggtct tgattattat ctagcaaatg caaaggttgc tgcagaaaga gtaaatatac
    11941 ctgtagcaat gcatctggac catggttcaa gttttgacct tgcaatgaaa gctttaagaa
    12001 gtggatatac atcaataatg atagatggtt ctcatgaaag ctttgaaaat aatatatcta
    12061 tatctaaatc agtagtaaaa gcatgtagtc cttctcttat accagtggaa gcagaacttg
    12121 ggaaagttgg tggaaaagaa gatgatttag atggcgggaa tagtaatgat tatacaaatc
    12181 caaaagaggc aaaagagttt gtcgatagaa caggaatatc ttcattggct attgctatag
    12241 gtactgcaca tggattgtat aagggtgaac ctaaaataga tttagatagg ttatcagaaa
    12301 ttaaaaatgt agtttcaata cctttagtat tgcatggagg ttcaggaata catgatgata
    12361 ttataaaaga agctataaaa agaggtattg caaaagttaa ctatgcaact gaattaagaa
    12421 ttgcatatag taaaggggtt aaaaaagttt tagatgaaga ttctgaggtt atagacccta
    12481 aaaagtatgg attagcaggg cttcaatcag taaaggattt tgtgaaagaa aagattaaag
    12541 tgtgtgggtc tgtaaataga gtataaaaat aaaatatcct aaatttattt tagataagtt
    12601 taggatattt gttatatgaa aaatttatat taattatatg taaatggtgt atttttttca
    12661 tttaattgat gaaaaatatc agcttttatt ggtaaagtat tacatatata attaaaatat
    12721 actaaaaatt gaactatata ttttattatt ataaaatatt tatattaaat tgtggaatta
    12781 aaatatacta ggatataaaa ttcttaaata aaaagaaaag gttgttttta taaaaaatat
    12841 tttttatacc actttaaaaa acacaataat aacactgagg gaggtgggga tatgagagaa
    12901 cgcattattc ttgaaacatt aaaaaatagt agtggttatc taaacataga ttattttgca
    12961 gataagttgg gggtatctac tcgaactatc agaaatgaaa taaaaaagat agaaactata
    13021 aaagaatgta atggttttaa attagaatat aagtctaaat taggatatat tctaaatatt
    13081 aaagaccaag ataaattcga gcattatcta agaaacttac cctcagattt agttgaaaat
    13141 ccagaacaac ggttggagtc tataatagta gagcttttag taaatgaagg ttataaaact
    13201 atagaacagt taagtaaaaa atttctagta agttcatccc aaataaaaaa tgatttaaaa
    13261 aagatagatg aaaagataaa ggatacagaa ttaaaactag agcgaaaggc tcattatgga
    13321 attaaaatag aaggttctat aaaagaaatt caaagtatat tggtggatag ttattttaga
    13381 gggaatagaa atataacaga gtacaggaat aagtttatag ataatttaaa attagctaat
    13441 attagaagta caataaaaaa tgtacttaat gaacatgatt tagaagcaaa tttaacagaa
    13501 cttgaggaaa tattagcaca aattattata ttgtatataa gagttagtat gagagtagcg
    13561 ggaaatgcta gcgatttaaa attatataca gaagatttaa ttatagataa attattagat
    13621 aaaattttta gagataaaaa atataacctt aattatgatg aaaagtatta tttaaaggag
    13681 cttataaaac taaagactaa agataagaaa gccactataa agaatattga taagaataaa
    13741 cttcaagata ttatgttcga attttttaga gagatagata aaaaatataa ctctaatttt
    13801 ttagaagata aagagttctt taacttattt tacttacata ttgcatgttt aatagaacgt
    13861 ataaagaaga accacaagat aataaatcct ttttcagtta aaataagtca acagtatcca
    13921 actgttttta atttatctat tcaattttca aaaatcatag aaaatgagta tcatataaaa
    13981 ataagtcaag atgaaatagg gtttatagct actcacattg ctgttccttt tgaaaagaga
    14041 gaagaagcta attttaataa aaaatataaa atagcaataa tatgctcttc tggtggaggt
    14101 agtgcatttt tgataaattt aagacttaaa gaaatttttc caaatgctga gataagaaat
    14161 ttttcattac tagaagaaaa agctgtaata gaatttgcac cagatttgat tttttcaata
    14221 acaaatcttt tatttgaaat aaatgctcca gttatactta taaatgaaat tttagacgaa
    14281 ttggattatt tagatattaa agaaagtgtt agatttgcag accatatagg aaatatatca
    14341 agcccaaaac aatatatatt aggtctattt gataagaatc actttaggtg tataaaagat
    14401 aaagctaagt ataaggatat ccttgatagt atgtcaaaat gtatagttga cgagggagct
    14461 tgttctccaa cctatcccaa agatgtatgg gaaagagaaa gctatttgag tactatttat
    14521 acaaatgggg tggctatacc tcatccaatc gagatgacag gaaacaaaaa tataatatca
    14581 gtagctttga tacaaactga tattatttat gaaaataggg tgcccaaaat tattttcatg
    14641 atttcattaa taaagggaaa tttagaactt cataagcaga tatctaaata tttaagtaag
    14701 attatggcaa ataaggatat ggtagacatg ctaaataagt cacaatctta tgaagagttt
    14761 atgtataagt taaaaatcta tctgggaggt tagacatgaa tatagagttt tttaagaggt
    14821 tgtcagaagc agatggtata gcatctaatg aagaagaggt tagacatgtt ttattggaag
    14881 aactaaaagc ttatagtgat aaaattatct gtgatgggct agggagtatc atcttttcta
    14941 aaataaaaga tgagagtgca ccaaacgtaa tgatttgtgc tcatatggat gaagttggat
    15001 ttatggtgag aagtatagac aaacttggta tgattcactt aataacaata ggaggagtaa
    15061 aacctcttgc acagtttgta caaaaagtta gaattacaac aaaagaaggg aagaaaatcc
    15121 ccgctgtcat aaatgctaca tataataatg gtaaggctga aaatatatat gcagatattg
    15181 gagcatatac agaagaagat gtatataacc tagggattaa tgttggggat atggtaacat
    15241 atacaacaag ctttgaggaa tttactttac cagaccgatt agtgggaaag gcttttgatg
    15301 ataggatagg atgttttgtg atgggagaag ttttaaaaga acttaggaaa gaaaatctaa
    15361 attgtaatat tcactttgcg gctacaagta gtgaagaggt tggaataagg ggagcaaaga
    15421 catcaacaca gttaataaat ccagatatag tatttgtaat agatgtagca tgtgctaaaa
    15481 atgagtttgt gagagactat acaaatcaga aacaaattga taaaggtgta atgctaatgc
    15541 atagagatag gactctagtc cctagtagaa aaatgataga ttatgtaatg gaaattgctg
    15601 ataaaaataa tataccactt caacatgata tgtttgaatc aggtgggact gatggaggag
    15661 aagcacatct cgtaaatgaa gggaaacctt gtgtagtaac ttgtgtacca gttagatatg
    15721 gtcattgtgc attttcaata gtaagtaata aagatttgga gaacattata agattgtata
    15781 cacagttaat tttaaatttt gatgaagaac aatataaaca tataagaaat tttatctaaa
    15841 ggagaataag aaaatgtcaa cagaagtaca aataatggaa cttatatcaa ctgcaggaga
    15901 gagtaaatcg aaagcttttg aggctttaaa aaaagtgaag tcaaaagatt ttaaaggagc
    15961 aaaattgtta atagaggagg ctcgtaaaat agatattgaa gctcacagga tacaaacaga
    16021 attaataact caagatttaa atgaagatgt tgaaagtcca gcaatgagtc ttttaatggt
    16081 acatgctcaa gaccactata tgacttctca gctagcaaaa gacttgatag aggctttgat
    16141 atattgtctc gataagtaat tgtaatgtag aaatagatta tttatgtaaa aattctttta
    16201 aaagtttaga tgcttttaag agataataaa aatacaaact ttaggaggaa ttattatgaa
    16261 aatattatta tgttgtgcag gtggattttc tactaatatg ttaatgcaaa atatgaaaaa
    16321 ggtggtaaaa gagagtgcta aactcaatga aaaagatttt gagtttacag ctataccagc
    16381 agattcaata gaaagtgaag ttgatgattg ggatatagta cttataggtc ctcaaatagc
    16441 tcacaaaata gacttcttaa aaggaatatt agagccaaaa aataagcctt ttgcagtaat
    16501 agataaagat gtatatggaa aaatggatgg agctacagtt atgaagttgg cattaataac
    16561 ttataagaaa catcaattag ctcaaggata ataaaaataa tgagggaaaa gggagattag
    16621 atatgttttc aaaatttgaa gcatttatga atagagtatt tatgccttta gctcataagg
    16681 ttgacaatca acgtcacctt ggttctataa aggctggtat ggttgctatg acaccattca
    16741 caatattagg aagtatattt gcaatacttc cagcacttcc aaatatgctt ggagaaaata
    16801 atccaataag caaattcata cttaacaatt cagcaatatt ggatttacca gtaagtcttt
    16861 ccataggttt aataggatta tatgcttgta tgtgtattgc ttttaatctg gggaactact
    16921 ataaattata tataccaggt tgtgttgcac tatcaacttt ttccttttta ttcctagtag
    16981 cctcatttac accagatgga gctttagaaa taggaaattt aggagctaaa gggctattta
    17041 caggtatgat agcagggctt ggttctgtgg agttatataa tttttgtaat aagaagaata
    17101 tcacaataaa aatgccagaa aatgtacctg attttgtatc taggtctttt gaattaatac
    17161 ctactactat aatagtttgt ggaactttta tagttgctcg ttttatttca ttaaaagtat
    17221 ttggagaatt acctccacag atacttactc aatttttatc tccattagta ggaagtatgg
    17281 ataacccatg gtcagttctt gcacttaact ttgctatatg tactatattc ttttttggaa
    17341 tacattcatc agtatttagt cctataacta gacctataat gattacattt atagctgaaa
    17401 acatagcagc tatgcaggct ggagaaacaa taactcattt ctttacagca ggagcttcaa
    17461 gtgcattctt tggatttaca ggatgtggaa ttagtatagg ttgtgtaatt gcatgtatgt
    17521 tatcaaaaaa tgcttcctat aagaagattg gacgtgtatc attattccct gcattatttg
    17581 ggataaatga accaatatta tttggagcac cgataatatt aaatccaata atgtttatac
    17641 cacatgtatt tggtggagct ataataggta cactaccaat gttttttatg cactggggat
    17701 ggttagcaaa gccagtattt gaccctccat atgtaggggt attcttagaa ggatttttaa
    17761 ctaatggaga ttggcattct atattagcaa atgcattgca attagtatta gcagttttat
    17821 tatattggcc attctttaaa ataatggaac gtcaacaaaa taataaaaaa caaaaagaag
    17881 aaactaagaa tatattctct aaagaagaag aagacttatt ggatgattta ggattggatt
    17941 tctaatattt tgttatgaat aatacaatgg agagattagt atccttaatc tataaaagag
    18001 gtgttgacgc tcttttgatt aaagcaaaaa atactaaaag atatatagga gctttatcag
    18061 gtagtggtgt atatgtgctt gttactaagg ataaaaatta tcaaattcta gatggcagat
    18121 atattgatga agcagataaa aaaacgactg gtttcataaa aaggattgta tctcaaggtt
    18181 cttatatacc aactataatt gagttattaa aagaattaaa tataaaaaag ttagcaatag
    18241 aaaaccaagc tatgagtata caagagtatc tttcactaaa aaatgaaggt tttgaaatca
    18301 atttaataac aaatgaatta tggaagctaa gggctataaa atctaaagaa gaaattgaac
    18361 ttattaaaaa ggcttgtgaa attacagatg aagtatttga tgaggttatt tctgaaatta
    18421 aaaaagatat gactgagcta gaagtatcag ctctaattca gtatcatgca ttaaaaaaag
    18481 gtgcaagtgg aatgtctttt gaaacaatag tggtatcagg agaaagaggt gcaatgccac
    18541 atggaagacc tacaaacaaa aaattgaaag tgaatgaagc tataacaata gattttggtg
    18601 ttgtttatca agggtatcaa tcagacatga ctcgtacaat atctataggt aaacctccta
    18661 aaattattaa agagatatat gatgtagtat tggaagcaca attatctgca atagagtcaa
    18721 taaaggaagg aactagggca agtgatgttg acaaagtggc tagaaaaatt atagataaac
    18781 atggatttgg caaatatttt aatcatggac tgggtcatgg tataggtctt ggagatggtg
    18841 aagtccccac tttaaatcca aatagtgaag atatattagt ggaaggaatg gtaatgtctt
    18901 gtgagccagg tatttatatt ccaaatgtag ggggagttag aatagaagat gacattgtta
    18961 taatagatgg aaaaggtgtt ccactcaata agacatccaa agagtttata atattaggag
    19021 agtaaaatta tgaaatataa ttttaataaa gtattaaatc gtaaagaagg aaattgtaga
    19081 aaatggagca accatgtgat taaagaaaaa ttcggcttaa atgaagatgc aattcctatg
    19141 gatttagctg atatcgattt tgagtgtgct cctgctataa aagaatctat cttaaaaaga
    19201 gcatcagtag gagattatag ttatactttt ataggagatg acttctatga tgcgattata
    19261 aattggaata aaagaagatt tgatgtatat atagaaaagg attggataaa attaactttt
    19321 ggtactgttt caacccttca ttatatagtc caagcatata ctaaagaagg agagggtgta
    19381 ttgataaata cacctgctta tgaccctttt gcagaggctg tagtaaataa taatagaaag
    19441 ttgtgttgta gctcattaaa attagataac aatagatatt atttagattt agaggatatg
    19501 gaaaatcaaa tgaaatacga gaatataaga ttgcttatat tctgtagtcc acaaaatcca
    19561 tcaggtcgta tatggacaaa agaagaacta tatcaagtgt cagagttatg tttaaagtat
    19621 aatgtaattt tggtaagtga tgaaattcat agagatataa tatttaaaga ttatagattt
    19681 gtatctttat ggaatgctca tccggaaatt tataaaaata gtataatctg tgtatctcct
    19741 aataaaggct tcaacttagg tggattaaaa acatcatatg tattaataag agatgtaaaa
    19801 attagggaga ctttattaga aaggctaaaa agtaattcaa taacttctcc aaatgtattt
    19861 gcaataccag caatcgttgc agcgtacaat gaaagcgaag aatggctaga tgctatgact
    19921 agttatgtag aggagaattt tgaaatagtt tatgatttct ttgaaactaa tataccaaaa
    19981 gccaaagtga tgaagtcaga ctcttctttt ttagcctgga tagatgtaag agaagtgttt
    20041 agaaatgaag aagaatctaa agactttttt agacatgcaa acttaactat ggtagttgga
    20101 agttattttg tgaaagatgg agatggattt attcgtatta atgtggggtg tcctagagaa
    20161 acattaaatg aggctctaaa tagaatcaaa aaaacgtata taagtatgta ttgttaaatc
    20221 ataaaaaaag tatctatggt ttatataaaa acacattatt tagttatcaa atattactgg
    20281 aattttgtat tccagtaata ttttttgatt aaggaatatt attgaggaat attaaataat
    20341 attatttcat acccttatat taacttatat aaaaatattt tattattttg gaaacgggtt
    20401 agctaacctt tatctagtgt atatttatat tgtaagaagc agtaaaaact tttcctttac
    20461 taagtttatt gataaacttc ttatctttat aaattttgtt agaatttata ctatcagcaa
    20521 gaccatacca aggttctata cataaaaaag gagcagtaga attagtttca ctataataag
    20581 gagtccaaat accaactaga gggaaatctt ccatagatat agttacatat ttactaccat
    20641 cattattaca tatagatact tcatctatgt tggtgtatat caaagcatca ttcttgaata
    20701 cttctggatt taactgtaag ttttttaatt ttccaatagg tattatatca tctgtaaaag
    20761 aaccatttaa attgattttt tctacatcat ttttactttt aaactcaagg tagtgtttag
    20821 aaaaatcatt ttgttcgtaa aaaggaaggt tgaatgcagg atgtccacct atagaaaaga
    20881 atatatcttt agaatcagta ttttttacaa tccattctac ctcaatacta ttatcattta
    20941 atgtatagtt tatgattagc tcaaaagaat atggatactt ctttaaagta gattcattat
    21001 ctgttaattt ataagttaca aatgtatctc ctttatctac aatctcaaag tccatatctc
    21061 tagcaaaccc atgttgagtc atgctatata aattttcttc tattattgtt tcattatcaa
    21121 aaagtttacc tactataggg aacaatatag gtgattgtct gccccaatat tttttattac
    21181 catcccaaag aatgtttttg tcgtattttt tagaaaatat tttagttagt tcagcaccaa
    21241 aactgcttga ttcgataatt aaattttcat tttgtaatat attcatttaa aatctccttt
    21301 attatatttt atgagtatat tatactataa agtataaaga ttattaaatt ttatttgata
    21361 ttatatttga aaggtagatt ttagtatatt ttgaaaattt tgttttgaaa atttgggatt
    21421 atttaagaaa ttttgtatta taaatagaag gaaatagata aattgtatag aataaaatat
    21481 attaagataa gttaataatg ttaaatggga agtgagttta tggaaaaacc aaatacaaaa
    21541 gttgttaact ttcaagagta taaagacaga aaaaaccaaa gagaagtaaa tagagacgaa
    21601 cttttaaagc ttataaaaaa aattgtgact tcaaaatagg gagttgttaa actccctatt
    21661 ttaatgggtt tcataataat taagacattc tgagtccatc tatataatct ttgaattgtg
    21721 agaaatctga ttcactactt aattctatgg tttctgaacc ttccgtataa aaattcttaa
    21781 gatagatagt ataattatta tcaacacaat catgataaat acatctatat ccatcttcat
    21841 acaaactttt taacttagaa aaatcatcca caatatcatc tccttaaagt tcttttaaat
    21901 atatttttac aaaaagcatc taattgtatg caaattgaca atgtaaaata aaggaaatga
    21961 acataaaatg tagaataatt tttatatgta tgtaaaaata aaaagaaaaa gttgaaattt
    22021 ttagaaaata agagtatttt ttatctaaaa agagagttta aaaaataaaa aaatgttggg
    22081 aggataaaaa atgagtttat tagaaagtat atcaaaaaac atatattccc tagataactc
    22141 ttctattgaa aaaacaaagc agagattgga taggcttata catccaactg gaagcttagg
    22201 aaagatagaa gatatttgca tgcaattagc aggaatattt ggcaatgaaa attttgacac
    22261 aagtaaaaag gttataattg cttttgcggg agaccatggt gtatatgaag aaggcgtagc
    22321 acctgaccct caaaatataa caaaattaca gtttccaaat ttttcgaaag gtctatgtgg
    22381 agttggagta ataagtaaat ttgtaggggc agatgttgta gctgtagatg taggaataaa
    22441 ctgtgatgaa aaactggatg gggtattaga ctacaagata agaaaaggga catcaaatat
    22501 ggcaaaaggt ccagctatga gtaaacaaga agcaattaga tgtttagaga taggtattga
    22561 aatagcagag cagtgtatag aaaaagatta taaggttatt ggtattgggg agatgggtat
    22621 agcaaatact actccaagta cagcaataat atctgtaatt tcagggtgtg acccgttaga
    22681 agttactggt ataggtgcag gtcttaagaa agaaagacta aagcataagg ctgaagtaat
    22741 tagaaaggct attgaaatta ataatccaaa tccaactgat ggagtagata ttttatctaa
    22801 agtaggagga tttgaaatag gctcaatggc aggtgttata ttaggttgta gtgctaatag
    22861 gattccagta gtaattgatg ggtttatttc ttatgcagca gcattaattg catataagat
    22921 aaatccaaaa actagagaat atatgatagc atctcattta tcagcagaat caggaactaa
    22981 aagagcatta gacatattaa aattagaccc tctattaaat atggatatga gattaggtga
    23041 gggaagtgga gctgctttag catttgatat aatagaagct tcaaactata cttataaaaa
    23101 tatggcaact tttgatgaaa ttgacatggg aagataaata taaaaattta atatgtagga
    23161 gtgttttgat gagtaaaatt attctagtaa caggaggagc taggtcaggg aagagtaact
    23221 ttgcagaaaa actatgtttt gacagaaata ataatacagc ttatatagca acctctattc
    23281 catttgatga tgaaatgaaa gatagagtaa aaaaacatca agagaataga cctagaaact
    23341 ggaatactta tgaaatatat gaagatatat attccataat taaggagata tataaagaac
    23401 atgaaactgt tatactagat tgtgtaacat tattagtaaa taatctaatg tttgaacaca
    23461 atctaaatat agaagaatct agtcaagaag aaataaacaa attagaacaa tacataaaag
    23521 aacaagttgt caaacttatt gaagaaatag aaaaaacaaa tctatacttt gtatttgtaa
    23581 cgaatgagtt aggtatggga attgttcctg ggaataaact tagtagaatt tatgctgata
    23641 ttgtaggtcg tataaatcaa tatatagctt cgaaaagtaa tgaagtttat tttgtagtta
    23701 gtggcatagc tatgaagata aaggagtagt atgcaattat gaaaagattt attttaatac
    23761 tacagttttt gacaaggata cctataaaat taaatgtagg atttgatgat gaattttata
    23821 agtcaatagt atattttcca cttgtaggtt ttgtcatagg tatattatcc tatttaatag
    23881 gatggatttc tatgctttta tttgaaccat ttatagcttc tataataata actctagctg
    23941 gtgtcttaat tactggagga cttcatatag atggattagg agatacattt gatgcaatat
    24001 atagttatag ggataaagaa aagatgcttg aaataatgaa agattcaaga ttaggtacaa
    24061 attcacttct agcaattatg tttgtacttt tattaaaggt tggattcgtt tacgatataa
    24121 taagtaataa ttcattgtgg gttataattt ttatgccaat gattgcaagg ttaggagtaa
    24181 tgttattgac atataaaact gtgacaccaa gagaaaaagg aatgggaaat ttatttatag
    24241 gaaaattaac tacaagtatg ttaataactg ctataatata cacattattg atagttgctc
    24301 ttattactaa atttatattt ttattaccta atatagtgtt gattaaagta ttaggttcga
    24361 ttatagtggt ttttgtattt ataatattat tcaaaaaaca tatttataaa aaaattgacg
    24421 gagtaacagg agatatatta ggctgtggaa tagaactttc agagcttgta tatttaattt
    24481 acatatattt gttaattttt atgttttttt aaagtaaaaa gtggtgataa tatgataaga
    24541 ttaatattaa taagacatgc actgacaaat gataataaaa aaggaagatt atcaggccat
    24601 ataaatagtt gtattagtga agagggcaaa ctacaaataa ataaaattac cagatatctg
    24661 agtaatgaaa acatagataa ggtttataca acaccatcta cacgtactaa agatacagta
    24721 gaaaaaatat caaaattgaa attattagaa atagaagaaa aagaagcttt aagagaaatt
    24781 agttttggag actttgaagg aagaactttt gaagaaatta aaatcaaata tccaaatgag
    24841 tttgaaaaaa tgataaaaga aggtaacaac tatagatatc caaatggaga aagtttgata
    24901 gactcttata aaagagtggc gaaagaaatt gataatataa ttttagaaaa tgatagtaat
    24961 ttagatacaa agacaatact tatatgttct catgcaggaa caataagaaa tataataaca
    25021 catttgattt ctggtagtta taagtatcac tggaacttta aaattgataa tgcatctatt
    25081 acagttttag aaattgatgg tggatttgct gtaatagata aaatgaattt tacagacttc
    25141 atataattta atcaaaacca aacattacaa tctgtgtttg taatatatct gtaaaattag
    25201 caatgaaaat agaatattag attaaaatta ggttcttaat tagatgttaa aagggaaaaa
    25261 ggttagatgc ctttgcagcc cccgctactg tgaaaccaac gaaactataa ataccactgt
    25321 cagtttgatg ggaaggttat agaagtagga tgaagttaag ccaggatacc tgcctaattt
    25381 aatttaaaac aagaggtctt cggggtgaaa gatttttaat taatatatat aaaagtccta
    25441 tctttagaag tattaggact ttttttattt gttttttagt aaattttaac aaggagggat
    25501 ggaaagtggg gaaaaaaata atgctacaag gaacagcttc aaatgtaggt aaaagtgtct
    25561 tagtagcagg tttgtgtaga atatttaagc aagatggtta tactgttgct ccttttaagt
    25621 cacaaaatat ggctttaaat tcttttataa ctaaagaagg attagaaatg ggaagagcac
    25681 aagtatttca agcagaggct gcgaaaatag agccaatagc tgatatgaat ccagttttat
    25741 taaaaccttc tggaaataat aaaagtcaag ttattgtaag aggtaaagtt gtaggagaaa
    25801 tgccttcttc taagtatcat gattataaat tggagttagt agatgtgttg aaggaaacat
    25861 ttaatagctt aaattcaagg tatgatattg tagttatgga aggggcagga agtaatgcag
    25921 agataaactt aaaagataga gatatctcta atatgggtat ggcagaaata gctgatgcac
    25981 ctgtaataat agtcggagat attgatagag gaggcgtatt tgcctcatta gcaggaacaa
    26041 tgcttttatt aaatgaagat gagaaaagaa gagtaaaagg tgtaataatc aataaattca
    26101 gaggaaaaaa agagctttta caagatggtg taaagatgct agaagacatc ataaaagtac
    26161 ctgttatagg agtagtacct tatacagata taaaaataga agatgaagac agtgtaacta
    26221 cgagatttaa gaaaaaaatg aataaaagtg atatacacat agaaataatt agaactccac
    26281 atatgtcaaa ttttacagat tttaatatat ttgagacaca agaagatgta agtattagat
    26341 atgtagacta tggagaatct ttaggaaatc cagatatatt aataatacct ggaactaaaa
    26401 gtactataga cgatttaaca tatataagaa aaagtggtct tgaatcgcaa atcaaaaatt
    26461 tacatagtca aggtaaattg atatttggga tatgtggtgg ataccaaatg ttaggtaaaa
    26521 aattaaaaga cccttatcat gttgaaagtg aaattgaaga agttgatgga ataggtcttt
    26581 tagatacaga aacaacgttt gagaaagaaa agactacaac acaagtagaa gctactattg
    26641 ttgaatgtat cagtgaatac atgaataatc ttaagggaaa aaaagtaaaa ggttatgaaa
    26701 ttcatatggg aattacaaag cgaggtaatg atgtaagaag tttagattta ataactaaaa
    26761 aacttgataa agaagtgaat tatactgagg gaagtgtaaa taaagagggg aatgtaattg
    26821 ggacttatct tcatggaata tttgatgaaa taagctttac aagagcaatt ttaaacaata
    26881 taagaaagaa aaaaggttta ggagaattag aaagcaaagt aaactctttt aatgaattta
    26941 aggataaaga gtatgataag ttggctgatt ttttaagaga acatttagat atagagaaaa
    27001 tatatgagat tatgaaataa tgatgacctt tatttataat ttaagtagga ggtgtattat
    27061 gaaaaaaatt ttaattgcgg gtactaatag tggagtaggt aaaacaacaa tatcattagg
    27121 aataatgcaa gctttggtta agagaaatat gaaagtacag ccatataaag tagggccaga
    27181 ctatatagac ccttcatatc acacttttat aactggaaga cattctagaa atttagattc
    27241 ttatatgtta gatgatgaaa aaataaagta tatagtaaat aagtcctcaa aagatgcaga
    27301 tatttcagta atagaaggtg ttatgggctt atatgatggc tttggaatag atttagataa
    27361 ttgtacaagt tcacatactt caaaggtatt aaagtcacct gttatattag ttataaatgg
    27421 taaatctatg gcagcatcta gtgctgctat ggtacttgga tataaggaac tagataaaga
    27481 tgtaaatata aagggtgtta tagtaaataa tgtaaagact aatagccatt atcaaataat
    27541 taagagttct atagaaaaat attgtaatgt tgaagtattg gggtattttc ctccaaataa
    27601 caaattctct ttggaatctc gacatctagg attagttcct agtgtagaaa tgaaatcact
    27661 aagggaaaaa ttttatacct tagcagatga aattgaacac tatatagata ttgacagaat
    27721 aattgaaata tcagaaagcg atgaatttga gagtgatttt gattttcaaa ctttaataga
    27781 aaataataaa ataaaagaac atgttaataa taaatcaata gctatagcat atgataaagc
    27841 attcaatttt tattatagag aaaatataga gcttttagag gaacttggtt tagaaataaa
    27901 ctattttagc cctcttgaag atgtatcagt gccaaatgca gattatattt atattggagg
    27961 aggttttcca gaaatatttg gaaaagaatt agaagcaaat gagtcaatga gaacttccat
    28021 attagaagca cataacaata atatacctat ttatgcagaa tgtggaggac tgatgtacct
    28081 aggtgagaaa ctattgaatc aagaagaaca agaatttaat atggttggaa tatttagtgg
    28141 aattagtaag atgacatctt ctttaaagag atttgggtac tgtattggtg tagccaagga
    28201 aaatactctt ttatctaaaa aaggggaatc tattaaaggg catgagtttc atcattcaat
    28261 atttgaaagt gatgaaaaat gtgtatattc aatgagaaaa gaaagagatg gaaatatagt
    28321 agaagagtgg gatggtggtt atagtaaagg aaacactttg gctacatatc ttcatactca
    28381 tttttataat aacttaaatt gtatagaaaa ttttttgaaa aaaggaaatg aataaatgag
    28441 tattttatct atttatatag gatatgtgac agacttaatt gtaggagacc catattcttt
    28501 tcctcatcca gtgagattta ttggtaaact tataaatttt actcaaggta taataagaaa
    28561 ggtctctaaa aatgataggc agttaaaatt tgggggattt atattatggt ttataaccgt
    28621 tggaataaca tatttaacaa cttatgttat agtgaagtta tttagtttta atatattatt
    28681 gagtattgta gtgaatagtt ttataattta tacaacatta gccacaaaat gtttaaaaga
    28741 cgaagcatta aaaatttata atgtattaaa aactgaagat atagaaaaat ctaggattca
    28801 gctatcttat atagtaggta gggatactac taatttaagt gaacctgaaa taataagagc
    28861 aactgtagaa actgttgcag aaaatactgt agatggtata attgcgccta tgttttatgc
    28921 atttattgga ggagcaccac ttgctatggc ctataaagct atcaatacat tggactcaac
    28981 agttggatat aaaaataaaa agtataaaga tattggtttt gcatctgcta agattgatga
    29041 tatagccaat tatataccag ctagaatatc tgtcattctt atgacaattg gaagtttctt
    29101 tttaaattat aactatagga actgttttaa aatctctatt agagatagaa agaatcataa
    29161 aagtccaaat tgtgcttttt cagaaggtgc agtatctggt gctctaggaa tacaactagg
    29221 aggtaccaac gtttattttg gggaaaaagt atataagcca acaatagggg ataagcttag
    29281 ggagatagat aaagaagata taattaaaac taataaaatt atgtatgcat cttcatttgt
    29341 atctatgttg gtatttacac taatatatgt gttatgtagg atgattttaa ttaacttaat
    29401 tatataaatt attgtttgtt aacttaaggg ggacatagat gaaggattta gggcatggtg
    29461 ccaatgtaga tgaaatggca agattatatg ggaaaaaccc aaaagaaata attgatttta
    29521 gttcaaacat aaatccaaat gtattaccaa atttagagag atacatttta aaaggattag
    29581 aagagtgtag gaattatcca gatataaatt atacaaactt gagagaaaat atatcaaaat
    29641 atatagatat aaatccagac tttataatac ctggcaatgg tgcaacagaa gtgatttatt
    29701 tgcttatgaa gagtattaaa aaaaaattgg ctataataaa tccgactttt tcagagtata
    29761 gaagaagtgc tgagttaaat aatttagata ttatagattt agagttagat ttagaaaata
    29821 actttaaact taatatagat ataataaaag aaaatataaa aagatttgat agtttattta
    29881 tatgtaatcc taataatccg agtggtaatg tccaagattt aaaggaactt gttcatttac
    29941 tagataaaca taataaggta ctaataattg atgaaacttt catggaattt gttgaagatg
    30001 aaagtaaata tagtttggtt aaatatatag aatcaaataa aaatatattt ataattaaag
    30061 ctgtgactaa gttttttggt atgcctggtt taaggctagg atatggtctt acaagcaaca
    30121 ctgaaattat gaacaaaatt tatgaacaca aagagccatg gactatcaat tcttttgcag
    30181 atatactatc caattttatt tttgaagata aagagtatat taaaaatagt aaagaatatt
    30241 acatagaaga aagaaaatat atgttacaag agttgagaaa cataagaaat ataaaggtct
    30301 atgatacaga tgctaatttt atcttgataa gaatatataa aaaaacaact aaagaattga
    30361 aaaaagattt gtttaagcaa ggaaacatat tagttagaga tgcatctaat tttataggat
    30421 tagatgatag ttttataaga gtggctataa aatctcatga agataacaaa attcttatag
    30481 aaaatatgaa aaatttattg ggtgattaaa atgaaatctt atggaatatg cccagcatct
    30541 tgtggagaat ttgtacaagg tataattgat gatgaagaat atttatgttc atatgcaata
    30601 gatatgtatt ctaaagtgta tattgaagaa aaattagtag atataaattt agggagatat
    30661 aagtcaaggt tagcaattga aaaggtattt gaaaaattta atttacctaa aaaatatact
    30721 aaaaatattt ctttaaatat aaatagtaaa atacctgttg gaaaaggaat ggcaagttca
    30781 actgctgata taggagctac tataaaggca acattatcat tgatagataa agatttaagt
    30841 agcgaggaga tttctaaatt agcagcagaa atagaaccaa cagattctat atttatagat
    30901 aaaaatagta tatttaatcc tctaaatgga actgttataa aatacctagg aaatctgacc
    30961 aatgcgaaag ttgtaatact tgaaccaaac aaagtactag atactatgaa aattagattg
    31021 aggcaagatt ataataaatt aaaagtagag aataaagaag taataaaaaa atcatttgct
    31081 cttttagaag aaggattgaa aaaaaatcat ttatctctag ttggagaggc ttgtactttg
    31141 agtagcttag caaatgagaa tatagaaaaa aaagagtatt taaatgaaat aataaaaata
    31201 tcaaaaaaat atggagcata tggagtaaat attgctcaca gtggaactgt agtaggtatt
    31261 ttaattgata agtctatgaa tgataaaaag atgatagatg ccttatgtga atctaacata
    31321 aattctgtct ataataaaat ttatacacaa aacataatta atggaggaat taagggggaa
    31381 atagaatgga atacataaag aatcctatga aaatagaaga aaaaagtttt gaattgatac
    31441 aagaaataat agacgaaatt agaccagatt ataaatttaa gaataatatc gaagaaaaaa
    31501 taataaaaag agctatacat actactgctg attttgatta cttagatata ttaaaaatat
    31561 cagaagaagc agttgatagt ataatagatg cattaaaaaa taatgcaagt atttatactg
    31621 atacaaatat ggctcttagt ggtataaata aaagaaagtt agaatcatta ggatgtaagt
    31681 ataaatgttt agtggcagat gatgaaactg taaaattagc taaagaaaaa ggaattactc
    31741 gttctatggc agcagtagaa attgcagcta aagaagaagg aagaaaaata ttcgttttag
    31801 gtaatgctcc aacagcttta tataaagtta tggagatgaa atcagaaggt agattagatt
    31861 tagatgcagt tataggagtt cctgtaggtt ttgtaggagc acaagaatca aaagatgaag
    31921 ttgaaaaaac agatatacca tatataattt ctaaaggtag aaaaggtggc agtaatttag
    31981 cagcagcaat agtaaatgct atattatata ctatgtaggt atctatatgg aagaatatgt
    32041 atatatagat ggaaaaaaat atagaagagg atatactaca ggttcatgtg caacaggtgc
    32101 atctaaggct gctgtatata tgttgattac aaaaaataga atcaatacta taaatataga
    32161 tactcctaag gggataccat tactactaaa agttgataat ataaatattt ctgatacatt
    32221 tgtggaatgt tccataaaaa aagatggtgg agatgatata gatgcaactc ataccatgga
    32281 tatttatgca agagctgaaa ttgtagctaa aaatgataag aacaaagggt atcttactct
    32341 aaaggatata gatagtttaa gcaccaatag tgagtgtaaa agtgagctct ataagtttat
    32401 tagggtttat ggcggaactg gtattggtgt ggttacgaaa aaaggtctta gcgtggatgt
    32461 tggtaaacct gctataaatc cgactccact taaaatgata aatcatgaaa taagaaagct
    32521 tataggagat aattttgaat ctatacttgg aaatgataaa gttttaaaaa taacaatctt
    32581 tgctccacaa ggagaaactg tagcaaaaaa aacatttaat ccaagattag gtatagttgg
    32641 aggaatatct ataataggta caactgggat tgttgaacct atgagtgatg atggttggaa
    32701 gaagtctcta tctatagaac ttcagatgaa aaaagaacaa ggcttagata aaataatatt
    32761 ggttccagga aatcatggag aacagtttat aagagaaaaa ttaaacatag atattaagta
    32821 tgtagttagg gtaagtaatt ttataggcta tatgattaaa gaagctcaaa gaataggata
    32881 taaaaaaatc ttaatggcag gtcatatagg taaatttata aaagtatctg ctggtatttt
    32941 taatactcat agtaaggtag cagatgctag aagtgagata ttagtggcaa acttagcttt
    33001 aatgggagct agatacgaat ttttaaataa aataaatcaa tgcgtaacta ctgaagaagc
    33061 tgtagagcta ataaataata gtgaatatag agaagtatat aatatattaa gtaataaatg
    33121 tagggagaga gtaaagcaat acttgaatga agattcagat gatattgatg tggaagtaat
    33181 catattttca atggataagt ctttattagg taaatcggat aatacagatg atttagtgga
    33241 ggtctttata tgataaacat aataggtcta ggacctggta acttagacta tataacaaaa
    33301 aaaggtgaaa atttaatttc cacttctgat gtattaattg gtggtaaaag aaatttagag
    33361 tctataaaaa attttgaagg agaaaaaata gttctggatt ctaatttaag agaaattata
    33421 gagtacataa ataacaataa agaaaagcaa atatcaataa tagcatctgg ggacccatta
    33481 atatatggga taggtagata tctatctaaa aatattgata ataagatgtt aaacatggtt
    33541 tctgggatta gttcattaca gtacatattt tcaaaaatat atgtagatat gaatgatgta
    33601 tatattacaa gtagtcatgg caaagtacca gattttgatt acatattatc acataaaaaa
    33661 gtatgtatgg ttacagattc aaagatagga ccaaaacaaa taagtagaga aataatagat
    33721 agaaatctaa ataaaattat tgttgtagga gaaaatctgt catatgacaa tgaaaaaata
    33781 acaatagcaa aaccagaaga gataataaga atggacaatt ttgatatgaa tgttgtggtg
    33841 attttagatg aggaatagtg agtttataac aggtaaagtt ccaattacta aggaagaggt
    33901 tagagcaata tcaataagta agttaaattt agtaaatgct aaaaacctca tagacatagg
    33961 ggctggtaca ggaagtgtaa gtgttgaagc tgcatataat tatcctaatt taaaggttat
    34021 atctatagag aaaaatgatg atgctataga gcttatagag aaaaataaaa aaaaattcaa
    34081 cttaaaaaat atagaagtga taaaaggata tgctccaatt aatctagggt taaatgttaa
    34141 agttgagtct atttttcttg ggggaacagg aaataatctg gaagaaataa tagaatggtc
    34201 taaaaaaaat ctcgttacag gaggaagact tgtagctaat tttataataa tagatacatt
    34261 taatcaaact ttaaaactgc ttaaaaagca tggatttaaa gaaatagatg tatgtgtttt
    34321 gaatgtttct aaactggaga aactaggaaa aggtgaatat tttaaaccac taaatcctat
    34381 atatataata tcttgtgaaa aaggggaaaa tgatgatgaa taaagtacat tttgtaggag
    34441 caggacctgg agataaagag ctgataacat taaaaggata caaattatta agtaatgcag
    34501 atgtagtgat atatgcaggt tcacttgtta atcctgaact tttggaatac tgtaaagaag
    34561 attgccaaat acataatagt gcacatatgg atttacaaga gataatagat gttatgagag
    34621 aaggtataga aaataataaa tctgttgtaa gactgcaaac aggtgatttt tctatatatg
    34681 gttcaattag agaacaagtg gaagatttaa ataaattgaa tatagattat gactgtactc
    34741 ctggagtaag ttctttttta ggggcagcat catctttagg ggttgaatat acagttccag
    34801 aaatttctca aagtgtaatt ataacaagaa tggaaggcag aactccggtt ccagagaaag
    34861 aatcaataca atcatatgct aagcatcaga catctatggt aatattttta tctgttcaag
    34921 aaattgagaa agttgtgtct aaattactgg aaggtggata tccaaaagat actcctatag
    34981 cagttatata caaagcaact tgggcagatg aaaaaatagt taaaggaact ttaagtgata
    35041 tagctgtaaa agttaaagaa aacaacataa ataagactgc tttaataatg gttgggagat
    35101 ttttaggaga agagtataat aattcaaagt tatatgataa ggatttcaaa catgaatata
    35161 gagggtaata ttgctataat ctgtattaca gaaaatggaa aaaaattagc tctaaagata
    35221 aattctctag taaataactg tgttatatat caagtaaaaa ataaaaaaag taatttagtt
    35281 gttgaagaaa catgtgtaca tacagttcaa aagaagttaa gtgattttgt aggagaaata
    35341 tttagcaaat ttgattacat agtatttata atggctacag gtatagttgt acgaagtata
    35401 gcaccataca taataagtaa gtttagtgac cctgcaattt tggtaatgga tgaaaaaggc
    35461 aaaaacgtaa taagtttatt gagtggtcat attggagggg caaacagctt gacacagtac
    35521 ataagtagtc ttattgatgc taatccagta ataacaacag ctactgatat aaatcaaaaa
    35581 gcttccttag atatgatagc aaaaaaacta aatgcacata ttgataattt tagagaaagt
    35641 gtaaaagaag taaattctat gctagtgaat aataaatgtg ttggattata tattgatgaa
    35701 ggatatcaag ttgatactag gggatttaaa cttatagaaa gtaaggatga gttaagagat
    35761 agtttttcaa acacatatat agaaaaatta gttgtagtaa gcaataaaat aaattgtatt
    35821 gaagatattg agaatttaaa cctagataat aaatttgaac attgctatag taccaaaaaa
    35881 ataataaagg taattccaag agatatagtg ataggaattg gttgtagaag aaacacagat
    35941 agtgaactga tgtataattc acttgaagag tttcttaata aacaaaatat agatattaga
    36001 gcaataaaca cagttggaag tatagaactg aaaaaagacg aaaaagcaat aattgaatta
    36061 tcaaaaatat tgaaggtgcc atttaaaaca ttttcagtag atgaaatatc taaggttgat
    36121 aatctttttg ataaatctga ttttgttaaa aaaaatgtgg gcgtgtattc agtagcagaa
    36181 cctgtagcat atcttttgag caaaggtaat ttgttagttg aaaaacataa atataaagga
    36241 ataacttttt cagtggggag aataaaaata tgatatacgt tgtaggaatt ggaccaggaa
    36301 gtaaagatac aatgacttta gaagcaataa aagcaataga agattctgag gctattgttg
    36361 gatataagac ttatataaaa ctaatagaag aatttataca aggtaaagaa ataatccaaa
    36421 atggtatgag gcaagaagtt gatagatgta aacaagcagt agaggaagca aaaaaaggaa
    36481 aaaaagtagc agttgtaagc agtggtgatg ctggaatata tgggatggca ggtcttattt
    36541 tagaattaat atctaaagaa gatgaagata taaaagtaaa ggtaattcca ggtgttactg
    36601 caagtattgg tgcagcagct atacttggag ctcctattat gcatgatttc tgtcatataa
    36661 gtttgagtga tttaatgact ccgtgggaag taattgaaaa aagattgaga ttggctgctg
    36721 aagccgattt tgtaatttgt ttgtataatc caagaagtaa gggaagaagt gaacatctaa
    36781 gcaaagcatt taaaataatg ggtgagttta aaggtggaga tacacctgtt ggagtggtaa
    36841 aagatgtagg tagagaaaaa gaagaaaagt ttgtatgtac ttttgaaaat atggactttg
    36901 aaaaagtcga tatgactaca atggttataa taggaaataa gtctacctat attaatggtg
    36961 aattgatgat aactccaaga ggttatacag tatgatttta attttaggag gaacttcaga
    37021 tagtttatct atatgtgata agataaatga actgaaaaat caaccatata tcctttcagt
    37081 tactacagat tatggaaggg aacttgcaca acaacatgca gagaatgtaa ttttaggtaa
    37141 gcttggaaaa gaagatatgc taaaatttat aaaagataat aatatagtaa aaataataga
    37201 tgccactcat ccttatgcag ttgaagtatc caaaactgct attacttgtg caaaactatt
    37261 gaatatagat tatataaggt ttgagagaaa atctttaatt gaagaaataa attatgataa
    37321 taaatttata gtagatacaa ttgaagaagc ctgtgaaata gcaaataaaa tagggacaaa
    37381 tatattcata ggaacaggaa gtaaaaattt gaacagattt atagaggaaa taagtgataa
    37441 aaatttagtt gttagagttc ttccaacgag tgaagtcata ttaagttgtg aaaaattagg
    37501 tttaagtgca gataatatag tagctatgaa aggtccattt agccagtata taaatgaaga
    37561 aacatataaa cattacaata tagatttagt cataacaaaa gaaagtggaa tagctggtgg
    37621 gttcttagag aaggtaaatg catgtaaaac tttcaatata ccagtaataa ttataaaaag
    37681 agaatcgatt aactacgaaa atgtatttaa tgacataaat aaaattaaag acatacttgt
    37741 gtaattttta ggaggagaat atatgaagaa agccttatta gtagtgagtt ttggtacaag
    37801 ctatcatgaa acgagagaaa agacaataga tatatgtgaa gataaaataa aaaattcgtt
    37861 aaaaagccat gattttttta gagcttatac atcaaatatg ataataaata aaataaaaaa
    37921 aagggatgga atagaaatag ataatccaat acaggcttta gataaaatat atgaacaagg
    37981 atatgatgaa gtaataatcc aaacacttca tattatatgt ggcgaagaat ttaacaaatt
    38041 aaaagaacaa gtagatggat attcttctaa attcaaaaag attgtattag gaagaccttt
    38101 gcttacacat attggagatt atcaggaagc tgtagaggca attaagcatc aaattcctca
    38161 tatggaaagt aatgaagcag tagtatttat gggacatgga acacttcatg aatcacattc
    38221 agcgtatcca gcattggaat acatgcttag ggataatgga ataaatgctt atgttggtac
    38281 agttgaaggg tatccagaaa tagaacatgt aataagaaga ttaaaagaag gaaatataaa
    38341 aactgtaaat ttgatgccat ttatgttagt tgcaggagac catgctataa atgatatggc
    38401 aggagatgaa gaagattctt ggaaaacaat attagaagaa aatggattta acgtaagagt
    38461 tcatttaaaa ggactaggag aaaattctta tatacaagat aaatttgttc gtcatgctgt
    38521 aaaatgtgca gagaatgcga agttctatgg tataggagca gggccaggag atggttcttt
    38581 acttacgata aaagcggtta atactttaaa gaaactggat attctataca ctccagaatc
    38641 aaaaaagggt ggagatagtc tagctttatc aatagttagt gaatatttac ctgaatcagt
    38701 ggaaataaag tctaggcatt tcccaatgag ttttgatggg aatgaaaaaa gtttagcttg
    38761 ggacaatgtg gcacaagaaa ttatatcaga tgttaatgat ggtaaaaatg taggatttgt
    38821 tacattagga gaccctatga tttatagtac atatgtatat ataatgaaaa gaatattagg
    38881 agaggtagaa gtcgaaacta taccaggaat ttcatcattt tccaatatag catctaatca
    38941 gaattttcca ttagtcatgg ataaagaagc tttagtggta attccttgta ctatggaaga
    39001 tgataagata gagtatgctt tgcaaaatta taattcaata gtattgatga aagtatataa
    39061 aaattttaaa gaaataataa aaaaattaga aaagtatgat ttaatagaac atgctatttt
    39121 agtaagtaat tcttcccaag aaagcgaaaa tgtgtttaca gatttaaaag aagcgcacct
    39181 tgaagataag atatcttatt tttctactat actagtaaat aaagataata aaataaaata
    39241 ggtgaaagca atatttaaag gagacttaat atgaatatag tggttggaac taggggtagt
    39301 aatctagcgc ttatacaaac agaatgggta ataaatgaat taaaaaagaa gtatccagaa
    39361 attagttttg agattaaaat cataaagaca aaaggagatt taattcaaaa tgtttcactg
    39421 gataaaatag gtgataaagg attgtttgtc aaagaaatag agcaacaatt attagatgga
    39481 aaaatagaca tagcagtaca tagtatgaaa gatatgcctt cttatttagc agatggacta
    39541 aaatttgctc atacgcctaa gagagaagac ccaagagatg ttctaatact tagagaagga
    39601 tataaaaatt tagatgattt gcctcatgga gcagtaatag gaacaggaag taaaagaagg
    39661 aagtttcaat tattgaaaca aagacctgat ttaaatatag tacaagttag aggtaatgtg
    39721 gaaactagga tacgaaaaat aaaagatgaa aacatgcatg gtattgtgtt ggcagcatca
    39781 ggaataatta gagctaattt acaagataaa ataagttctt atttacctgt tgatgttgtt
    39841 attccagcac ctgcccaagg agctttagct atagaaatta gaagcaatga tagtacgata
    39901 gagggaatag taaattcact gaaggatgag aatacagaaa tccaaatatt ggctgaaaga
    39961 ggttttttag atggtgtaaa tggaagttgt catattccaa tggcagctta ttgtgaaata
    40021 atccaagata aaatacatct tactggctta tatggagatt cagaaggaaa aaaagtagta
    40081 atcaagtcta tagatggaga tatttcttct cctagagagt taggtttaaa gttagctaaa
    40141 cttgtattga aggagtatga gaattatgaa gggtaaggtt tacttagtag gggcaggacc
    40201 aggtgattat aaactcatga ctttaaaagg tttagagtgt ataagaaaat cggatgtaat
    40261 agtatatgat agattagcaa atagtagtta tttaagagaa gctaagcctg attgtgaact
    40321 tatatatgta ggcaaggcat caagtaatca tattttgcca caagaagata taaatagaat
    40381 tatagcagaa aaagctaaag aaggaaaaat tgtaactcgt cttaaaggag gagaccctta
    40441 tgtatttggt agagggggag aagaagcaga gactttagta gatgaaggta tagaatttga
    40501 agtagttcca ggtataactt ctgctatagg aggtttatgt tatgcgggta ttcctataac
    40561 acatagagac catgcttcat catttcatgt aataacaggt catttgaagg gtgatgatag
    40621 tggagaatta aactggaatg ctcttgcaaa taacaaaggt actcttgtgt ttttgatggg
    40681 aatttcaaac ctagagaaaa taagtgaaaa cttaatgaaa gaaggaaaag ataaggatac
    40741 acctgttgct cttataagtt gggcaactag atataatcaa agagttgtta catctacact
    40801 tgaaaatgtt tatgaaactg ctattaaaga agaagtaaaa ccgccaactc ttatagtagt
    40861 tgggagtgtt gtaggactta gagaaaagtt gaacttcttt gaaagtaagc ctttatttgg
    40921 aaaaagtatt gctgtaacta ggtctagaaa tcaaaatagt gtattggtag aaaaaataat
    40981 ggatttaggt ggaaatccta tagaaatacc tactattaag gtagaaaaaa tacaaaataa
    41041 tattaactta gaaaatgaaa taaaaaatat aaataagtat aattatctaa tactaactag
    41101 taaaaatgcc gtagaaatct tctttgaaaa gatatatgaa atgaattttg atttaaggat
    41161 attatctaat ttaaaggtat gtgctatagg ttctgctaca tcaaatgagt tgaaaaaaag
    41221 aggaattata gcggatatag taccaaaaaa atttgtagca gagtcactgt atgaagagtt
    41281 agctcctatt ttaaatgatg acgataatat acttatacct agagcagaaa atgctagaga
    41341 ttatctggtt gacaaactta aggctatttg tgaagtaaca gaagtacata tatatagaac
    41401 agtaatagat gaggagaaaa aaggtgagat attagatatt ttaaattcta atgacataga
    41461 ttatataaca tttactagtt cctcaacagt aaataatctt gttgaaatta taggaaaaga
    41521 aaatattaaa atattagaaa aaataaaaac actatctata ggtcctataa ctacagagac
    41581 aataaatagt ttgggaataa aattgtacaa agaatctgct acatctacta tagattcgtt
    41641 agtagattta attataaaaa attaattttg gaggcttgaa tatgttaaga agaccaagaa
    41701 gactaagagc aagtaaagca atcagaaatt tggtaagaga aactaaggtg aatgtagaag
    41761 atttaatata tccactgttt gtagtagagg gggaaaatat aaaagaagaa attaaatctt
    41821 taccagatgt ctatcattta tcaatagata tgctagaaga cgaaataaaa gaaataagtg
    41881 agttgggaat tgaacatata atgttatttg gtgttccaga tgaaaaagat gagtgtgctt
    41941 cacaagcttt taatgataat ggaatagttc aaaaggcaat tagaaaggta aaagaaataa
    42001 attcagatat aaatgtaata acagatgtct gtatgtgcca atatacaagt catggacatt
    42061 gtgggatttt aactgatact ggttatgttg ataatgataa atcattggag tatttggcta
    42121 aaatatctgt aagccatgct aaagcaggag ctgatatggt tgctccatct gatatgatgg
    42181 atggaagaat acaagcaata agagaagctt tagatgaaaa tggattagaa aatgttggaa
    42241 tcatggctta tagtgttaag tatgcttcaa attattatgg accttttaga gaggcagctc
    42301 attcagcacc atcttttgga gatagaaaaa catatcaaat ggacccagca aatagcaatg
    42361 aagctataat agagactgaa cttgatatat tggaaggtgc agatatactt atggttaaac
    42421 ctgcattatc atatttagat attataagaa gagttaaaga taattttgac ttacctctag
    42481 cagcttataa tgtaagtgga gaatactcta tgcttaagtt tgctgtgaag gaaggtttat
    42541 taaatgaaga tgtaattctt gaatcaatta catctataaa aagagcagga gcagatataa
    42601 taataactta ttttgctaaa gacattgcta aactgttgaa aaaataaatt ctagtagtat
    42661 aaagaatatc aaaaagtata ggaattgtaa ttaactatta tacagtagtt ttgtttagac
    42721 atttattgaa gaataataga aactaatttg caatttctat actttattta tgtaactaaa
    42781 taaaatttgg aggtagaaga tgctatatcc tattaattta aaattagatg agttagatgt
    42841 agttataatt ggtggtggag aagttgcata taggaaatgt aaaaattttt tagagtttaa
    42901 caaaaatgtt actatagttt ctaaacaaat tttaaataaa ttttatgatt taaaaggaaa
    42961 tataaaaata ataaaagatg attataaaga aatatatata aaagatgctt ctgtaataat
    43021 tgctgccaca aataatagag agttaaatat ggaaatagga ttatattgta gagcaaaaaa
    43081 taagctagtg aatgtagttg ataatataga aatatcgaac tttactgttc catcatatat
    43141 aaaaagagga gatttactta taagtgtgtc tactgggggc aagagtcctt cattatcatc
    43201 aaagataaaa aaagaaattg aagagagata tactgaagat tatgaggagt atttaaatgt
    43261 attaggagat ataagaaaaa aggttataaa aaaatacgaa gataaaagta aaagaaaaga
    43321 tgtgcttaat atgttggtaa cacttgacct agaagaactt aagaagtttg atatataaaa
    43381 aataaaataa aaaatgttaa aaaggtgttg acggattatt tttaagatga tatagtatta
    43441 cttgtcctta a
//
LOCUS       DAEPUT010000030        42871 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.031, whole genome shotgun sequence.
ACCESSION   DAEPUT010000030 DAEPUT010000000
VERSION     DAEPUT010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42871
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.031"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..614
                     /locus_tag="KRL22_001741"
     CDS             <1..614
                     /locus_tag="KRL22_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1272237.1"
                     /translation="YLMLILISSLCVIVYSYKITSLYIFKNFKIGILLFFYFLFSQII
                     FGLIISDNQFDYKNFLNYILLPIISLVYIYPFLCEEYGWRSFLQSILFDRFGKKIGIV
                     MVGTCWSLWHLPLQFTLYSPQTPIIGAIAHLIYGIGLSIFLGYVYMKTKNIWFCSIMH
                     VLINSLGLIFNDSEIIINYNSIIQRLIFILLFYTPFLFTKEYK"
     gene            994..2520
                     /locus_tag="KRL22_001742"
     CDS             994..2520
                     /locus_tag="KRL22_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1272238.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKVAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            2548..3105
                     /locus_tag="KRL22_001743"
     CDS             2548..3105
                     /locus_tag="KRL22_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272239.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDSLIGTIITIPFIVKKSNI"
     gene            3627..4670
                     /locus_tag="KRL22_001744"
     CDS             3627..4670
                     /locus_tag="KRL22_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272240.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VESEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            4781..5923
                     /locus_tag="KRL22_001745"
     CDS             4781..5923
                     /locus_tag="KRL22_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1272241.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKAKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
     gene            6377..7768
                     /locus_tag="KRL22_001746"
     CDS             6377..7768
                     /locus_tag="KRL22_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH1272242.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            8021..9814
                     /locus_tag="KRL22_001747"
     CDS             8021..9814
                     /locus_tag="KRL22_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1272243.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(9895..11277)
                     /locus_tag="KRL22_001748"
     CDS             complement(9895..11277)
                     /locus_tag="KRL22_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH1272244.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGFSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            11535..11882
                     /locus_tag="KRL22_001749"
     CDS             11535..11882
                     /locus_tag="KRL22_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH1272245.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            11900..12934
                     /locus_tag="KRL22_001750"
     CDS             11900..12934
                     /locus_tag="KRL22_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272246.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(12983..14032)
                     /locus_tag="KRL22_001751"
     CDS             complement(12983..14032)
                     /locus_tag="KRL22_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1272247.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            14307..15842
                     /locus_tag="KRL22_001752"
     CDS             14307..15842
                     /locus_tag="KRL22_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272248.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVTIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(16027..16713)
                     /locus_tag="KRL22_001753"
     CDS             complement(16027..16713)
                     /locus_tag="KRL22_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HBH1272249.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            16838..18220
                     /locus_tag="KRL22_001754"
     CDS             16838..18220
                     /locus_tag="KRL22_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1272250.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            18622..19890
                     /gene="eam"
                     /locus_tag="KRL22_001755"
     CDS             18622..19890
                     /gene="eam"
                     /locus_tag="KRL22_001755"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HBH1272251.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(19983..20339)
                     /locus_tag="KRL22_001756"
     CDS             complement(19983..20339)
                     /locus_tag="KRL22_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272252.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(20490..21584)
                     /locus_tag="KRL22_001757"
     CDS             complement(20490..21584)
                     /locus_tag="KRL22_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1272253.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
     gene            22048..22869
                     /locus_tag="KRL22_001758"
     CDS             22048..22869
                     /locus_tag="KRL22_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBH1272254.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            22890..24086
                     /locus_tag="KRL22_001759"
     CDS             22890..24086
                     /locus_tag="KRL22_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBH1272255.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            24253..27651
                     /locus_tag="KRL22_001760"
     CDS             24253..27651
                     /locus_tag="KRL22_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH1272256.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDMGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYSSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            27661..29334
                     /locus_tag="KRL22_001761"
     CDS             27661..29334
                     /locus_tag="KRL22_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH1272257.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLEPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            29607..29801
                     /locus_tag="KRL22_001762"
     CDS             29607..29801
                     /locus_tag="KRL22_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HBH1272258.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    29970..30203
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            30280..31677
                     /gene="asnS"
                     /locus_tag="KRL22_001763"
     CDS             30280..31677
                     /gene="asnS"
                     /locus_tag="KRL22_001763"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBH1272259.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(31850..33025)
                     /locus_tag="KRL22_001764"
     CDS             complement(31850..33025)
                     /locus_tag="KRL22_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1272260.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            33444..34808
                     /locus_tag="KRL22_001765"
     CDS             33444..34808
                     /locus_tag="KRL22_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1272261.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            34830..35321
                     /locus_tag="KRL22_001766"
     CDS             34830..35321
                     /locus_tag="KRL22_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1272262.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            35594..36265
                     /locus_tag="KRL22_001767"
     CDS             35594..36265
                     /locus_tag="KRL22_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBH1272263.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            36350..37216
                     /locus_tag="KRL22_001768"
     CDS             36350..37216
                     /locus_tag="KRL22_001768"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBH1272264.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            37249..38751
                     /locus_tag="KRL22_001769"
     CDS             37249..38751
                     /locus_tag="KRL22_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBH1272265.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            38881..39333
                     /locus_tag="KRL22_001770"
     CDS             38881..39333
                     /locus_tag="KRL22_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBH1272266.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            39493..40296
                     /locus_tag="KRL22_001771"
     CDS             39493..40296
                     /locus_tag="KRL22_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272267.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDAIDLSEARKYICELEKISKRFV"
     gene            40354..41241
                     /locus_tag="KRL22_001772"
     CDS             40354..41241
                     /locus_tag="KRL22_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH1272268.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            41260..42108
                     /locus_tag="KRL22_001773"
     CDS             41260..42108
                     /locus_tag="KRL22_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1272269.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            42171..42860
                     /locus_tag="KRL22_001774"
     CDS             42171..42860
                     /locus_tag="KRL22_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1272270.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
BASE COUNT        16892 a         4663 c         7316 g        14000 t
ORIGIN      
        1 tgtatcttat gttaatttta ataagtagtt tatgtgttat tgtttattct tataaaataa
       61 caagtttata tatttttaaa aattttaaga taggtatttt gctatttttt tactttttat
      121 tttctcaaat tatttttgga ttaataataa gtgataatca atttgattat aagaatttct
      181 tgaattatat tcttcttcct ataatatcat tagtatacat ttatcctttt ttatgtgaag
      241 agtatggttg gagatctttt ttgcaaagta ttttatttga tagatttggc aaaaaaatag
      301 gtattgtaat ggtaggcact tgttggagtt tatggcactt acctttacaa tttacactat
      361 atagtcctca aactccaata attggagcta tagcccattt gatatatggt attggacttt
      421 ctatattttt aggttatgtt tatatgaaaa ctaagaacat atggttttgc tctataatgc
      481 atgttctaat taatagcttg ggattaattt tcaatgattc tgaaataatt attaattaca
      541 atagtattat acaaagattg atatttatac tattatttta tactcctttt ctatttacaa
      601 aagaatataa gtaagaatta caattaattt atataaaaaa aatttttaag taaatatttt
      661 tatagagaga ttgttatatt acatatcata aaaatattaa actaactaaa tcaataaaaa
      721 agttggtggc taacaattta taattgttag cacaacatca tcttatgtat tgaaatctaa
      781 aatatcctca tttttactta gcataaatac tattaattaa gaaaataata tagaaattat
      841 aaatatatat aagtttagtc tggtgtataa aacaagaaaa ctaagtgatt tttaatttag
      901 ctttttatta agcttatttt ttatactatt tataataaat aaactccatg atgggaaaac
      961 tattactatt taatatgtaa aggagtattt taaatgaatg aatcatattg gtttttaaac
     1021 tcaagtccaa aagaatataa caaattaggt gaaaatataa aaacagattg tcttatagta
     1081 ggtggtggaa taactggatt gacaactgca tatttattag caaaagaagg taaaaaagta
     1141 gtgcttgttg aggctgataa aataggatat ggaacttctg gaaggaatac tggtaaggta
     1201 acttgtcagc atgatatatt ttactctaag atagagaaaa aatatggatt agataaagca
     1261 aaatcatatt ataatgcaaa taatgaagct ttaaatttag ttgaacaaat aatagaagaa
     1321 aacaatataa aatgtgattt taaaagggaa acttcttttg tatttacaga aaaagaggat
     1381 actataaaga atattaaaga tgaatatcgt acatgtaaaa aaataggaat aaattgtgag
     1441 tatcatgaaa ctatagaaaa tattccatta gatataaagg gggctattag ttttactaat
     1501 caaggtcaat ttaacccaaa gaagtatatt gatggattgg caaaagtagc agtaaattta
     1561 gggctaaaaa tatatgaaaa tacaccagta gtagaccttg aaaaaggaaa aatatgtagg
     1621 gttaaaacaa gagaagataa tataatagaa gctgagaatg ttataatttc atctcatagt
     1681 ccatggtatg atggattgaa tttttatttt gcaaaagaat atgcagagcg tgcttattta
     1741 atggttgcag ttttggaaaa taaattagca gatggtatgt ttataagtat agatgaccca
     1801 tcaataactt ttagacaata taatgatgga agtgaaaatt tactgatttt tggaggagga
     1861 gaccataaag ttggtcaggg aggaactgag aaagaaatat ttgatgattt agagcattat
     1921 ggtaaagaag tctttaaggt aaaagatttt aaggggaaat ggtctgctca agataatatg
     1981 agttttgaca atgttcctta tattggttat atcaacaaaa gagaagacaa tatttatgta
     2041 gctacagggt tctctaaatg gggaattact aatggaactg ctgctggaat aataataaaa
     2101 gatttgataa taaataataa ttctgattat aaagatactt ttaatccatc cagattaggt
     2161 agctactttt caaaagattt tataaaggaa aatgcaaacg tagcaataaa ttatgtaagt
     2221 ggaaaattaa aaataggtag tggagatatg cctaaaaata atggagaagg aaagattgtt
     2281 aatattgatg gaaaaagata tggtgtatat aaggatgata atggagattt ttatattgta
     2341 gacacgacat gtactcattt aggatgtgaa cttaatttta acagtgaaga aaaaacatgg
     2401 gactgtccat gtcatggttc tagatttgac tataagggaa atatacttga aggaccagct
     2461 cttaagccat taaaacttta tggacatggt gataatgatg ttaatcctaa gttattataa
     2521 aattattttt aggaaggtaa agtgtatatg aataaacttt taaagccaat aactatacta
     2581 ttgtatatag tttatatttt atctgccgta ttttttgtag caaacaaaga atatggaagt
     2641 ctaggtctag tagcaattag tttagttggt actttcattt tgagttttat aaataagcaa
     2701 actgaaagat tattaagtaa agaattatat ataatgcttg ctttatttat aatgttttca
     2761 tcattgttag gtacttgttt taatttttat gatataaatt attatgatga ttttttgcat
     2821 ttatggtcag gtataatatc ttgtattgtg gctttttcta taattaaata cttttataca
     2881 caaagagaga taagtaaaat gagtaaagtg tttttagtta tatttttatt tatgtttagt
     2941 atgggagtag cgagtttatg ggaaataggt gaatttttaa tggatacttt tgttgggact
     3001 actacacagg ccggagggtt agaagatact atgattgata tggtagattc tttaataggc
     3061 acaattataa ctattccttt tatagtaaaa aaatctaata tatagtttta aattttttat
     3121 attaattata atggatttaa ttaatcatgt tgagtttcaa ggtctatatg attaattaaa
     3181 tccatttttg ttatttataa ttattattga atatattttt acatataaga tataaggtga
     3241 tagatagaaa ttgttggatt atgtaaataa ttaatatata ataccattat gggcaataaa
     3301 tacaaatcaa atgataatat agtctattta tgtaaatgtt atattgtatc ctaagtataa
     3361 tagtaagttt tttgatagtg gtgtagaaag taaaaatcta ctagcctaaa ttgatgtatg
     3421 gattagttta ggaacagtaa ttgcatatct taagtttgat gtcatgttgg gctactagaa
     3481 ataggtcatc tttttcactt gaatatcttt tctttaaaca tggggagtat catatcaaaa
     3541 acatatgaaa attaagtgat ttataagaac agtaatattt tatatgatag tatagaatag
     3601 taataaagta ttaggaggaa cattgagtgt taaaaaagtg gtttggtatt gtgaaaaaaa
     3661 gacaaaaaag tgagtcagta aaagaagaag gtgaagtaat attaaaaaac gaaaaaatat
     3721 tatctgaaga aaagttgata gatgaagaag gagttgtagt taatattgat aatgaaatat
     3781 taactaaagt agaagtagta aatgatgata atgaaataga agaaaaaata atagaagaag
     3841 attggttaat tagtgaaaat accataaaat tagatgataa agaagcaatt attaatgata
     3901 aaaacataga attatgtaaa aaagaagttc aagttgaaag tgaaaaaata ggtttaaata
     3961 agtttgaagg acttgaccaa aatgaaaatt ataatctaga aaaaaatgtt attgaagaaa
     4021 aaaaagtaag tgaatgtttg acagaagaag atttagagta cataaaagaa attaaaataa
     4081 aaagaggaaa aagtataaaa gctataaact tgtatactaa agaagagtgg gtttttgaca
     4141 ctcatataca gtgtagtaaa aaactcaaag ttccattagg gtacataaga gaaaatttaa
     4201 aatatggata tatggattac tttggagatg caataaatta tttaagtgaa gtattaaata
     4261 tagatgaata ctgcaaaagt gaatggagct atctcgataa tagcaaatct ccatctgaga
     4321 tatttaatat tctaaacaat aaaatattta gtataaggct ttctaatgaa aaaagaaatg
     4381 aaattttgac aaatgataaa attgaagcat taaaaatgaa ttatagattt gaatgtattg
     4441 atgaagaata tgatgaatat tttaaaaaat ataagtctat aatcaaaaga ggtggaaaga
     4501 aaaaagttga attagtaaat aaaaaaggtg acattttaga aatatttaag tctttagaag
     4561 aatgtgccat ttatttgcaa aaggaaaaga atgaagttat acaaatgtta aaatatgggg
     4621 atacaaaagt aggaagaaac tttataaggt atagtttgag aagtatttaa tttcatttta
     4681 aattcataag agtttcattt ctgattcaca catttaatat tattttaatg taaaataata
     4741 aaggtgaagt attgcacaat taaaattaag gagggtatta atgtctgaag aaaaaaatcc
     4801 aaaagaaaat acattagatg aatctaaaaa ttcagataat gtaaattcta aaaaagatga
     4861 tgtgtcagat gaaaaaaata ctgataacaa agttaaaaaa agggaaataa agctaaacaa
     4921 caaaacactt aaagctattg tagcaattgt tgcagtagga gctatatgtt taggtggagg
     4981 ctatgttttt ggcaaagaag ctggaagaaa attgcctgct acttcaaaac actataatag
     5041 cagtgaggta gtagctacta ttggggataa aaaaataaca ggtgaaatgt taagaaagag
     5101 aatggagcca ttattttatt taaatgcaaa aactactatg actgatgacg aaatacgttc
     5161 atatgaatca aatatgattg aaactatgat tacatctgat atattatcct ctgaagcagc
     5221 aaaagagaaa ataagtataa ctaatgacca actagatgct cagtataata atttaatgag
     5281 tagtatagaa tcagcaatgg gaatgactaa agaagagttt ttaaaacagt ttgatttgac
     5341 tgaaaaatat ataaaagatg atatgaaaaa agagctagta gcatcaaaat atttaaatga
     5401 aaaagcaaaa gttactgata aagaagcaga gaactattac aataaaaaca agagcaatta
     5461 tttacaagtt agagcttcac atattttaat aaaaactgtt gatgataaag gtaagcaagt
     5521 tagtagtagc aaaaaagctg aacttaagaa agaagctgaa gaaatactta aaaaagccca
     5581 agctggggaa gattttgcta ctctagctaa aaaatactct gaagatagta gtgcagaatc
     5641 aggtggagat ttaggtttct ttggtaaagg tcagatggtg gaatcttttg aaaaagcagc
     5701 ctttgcattg aagaagggag aggtatctaa caaacttgta gaaagtgatt atggatatca
     5761 tataattaag aaaactgatg aaaaatatca gccatttgaa gaggtaaaat cagatttagt
     5821 aagcagttta acatcagaaa aacaaaacct acttatacaa aatctaaaag aaaaatataa
     5881 tgttaaaatt acagataaat atcaaatgaa agctaaagaa tagataaagt caatttatta
     5941 aaaaaaagaa aaattaactg tatggataaa agctattttt actctcaata tagagagtat
     6001 aaaatagctt ttattatttt gcaataaaat ctatttatat atatgaagtg acaaagaaat
     6061 aacatgcaaa aagacattaa aaagaaatat ttttaatttg aatttttttg caaaaaattt
     6121 acaaaaatga aaaaataaac aaaaaagaat tgaagattta agttgttatt taaatatata
     6181 tatattaaga ttttcttctt aagatactaa aaaaataata tttttcataa ttttaaaaat
     6241 aataataaaa aaatgaaaat acaggcgata atctattgag taaacataga aaagatgata
     6301 ttataagtat gtgctaaaat ggttaaagca atattaatat taaatttaac tataaaacaa
     6361 aagggggcgt ttttttatgt caagtacaga aagcgtatct aaaaaaagtg gtcatccgaa
     6421 gagtttttgg cttatttgca tgacaatttt gtgggaaaga tttagttatt atggtttaac
     6481 agctttattg gtattatttt ttacagcaag tgtagctcaa ggtggtttag gtctttctac
     6541 tcaagaagca acatccatgt ttggcttatt tacaggtctt atatatctta caccattagt
     6601 cggtggctgg ttagcagata aagttttagg tcaacaaaaa tgtatttcta taggtgcact
     6661 tttaatagca ataggagatt tcgtactatt tgcttcatct acatctattg caatggtttg
     6721 ggtaggtcta tcaataatta ttttaggaaa tggttttttt aaatcaagtt gctcaaatat
     6781 agttggggat atatatccta aaactgatgt gtcaagaaaa gatgcagcat acagtttatt
     6841 ctatatggca gtaaatgtag gagcatttat agctccaata atatgtggat tgctttctga
     6901 taatgtattt gcagtaagag gagcaagtgg agatatagta tcttatggat ataagatggc
     6961 atttttaatt tgtggtatag gcatgatgtt aggtatgatt atatttacac ttcttgcacc
     7021 aaaattatta aatgaagtcg gaaaatatcc tgtgactaaa ggtaataaag gtgaaaaaat
     7081 tgagtatgga ccacttacta agttggagaa aaataggata atagcaatgg ttattttatt
     7141 tttatttgtg gtcttattct ggacagcata ctatcaaaca caaagttctt ttatgattta
     7201 tgtaagggat aatgtaaata gaactctatt tggatttgaa atgccagtag catggcttac
     7261 atcactaaat gctatattat gtgtggcttt atgcccagta ttagctaccc tatgggttaa
     7321 attatctcat accaaaagag gtgatttctc tattccagtt aaaatgggat taggaatgat
     7381 aataatgggt gttgggttta tagttatggt atttgctaca ttagctaatg gtccagatgg
     7441 aatggtaaag gctagtatat tgtttatagt attgacttat atatttacaa cagtaggtga
     7501 attattctta tctcctatag gacttgcaat gttcaataaa ttagctccag ctaagtatgc
     7561 tacgttgtct atgggagcct ggtatctaac aagttttttt gcaagtttat tatcaggaaa
     7621 gattgctggt tttacagcca cacttggttt tttacagata tttggaggaa tagcaacagt
     7681 tttaataata tttggtttaa tattattggg aataagaaat gtattaacaa gattaatggc
     7741 tatggattta ctaacaaaag aaaaataatt catgacgaat tattgtaaat aaatgaatta
     7801 ctttaaataa aggaagttac atttaaatat aaaattaaat gtaatttcct ctttgattat
     7861 gaaaaaaagc tttacacaaa tagatattat aattaaaatt ataattgtga taattagagt
     7921 gtataagatt tatataaatt atacaaaaaa tatttatgta ataaacttta catacttata
     7981 tatttagtta ttcaaactat tatttcgagg aggtcttgtt gtgaatataa aagatagatt
     8041 aagtggatta agaaaattta tggaagaaaa aaatatagat gcctatatga ttccatcttc
     8101 tgataatcac caaagtgaat atgtaggaga ttacttcaaa tcaagagaat ttatatcagg
     8161 gtttaatggt tcagcaggga cggttattgt gactaaagac gaagctgggt tatggacaga
     8221 tggaagatat tttatacagg cagaatctca attagaagga agtacaataa aattattcaa
     8281 aatgggacaa gaaggttgcc caactacaga tgaatattta tataaaaata ttcctgaagg
     8341 aggaacttta ggatttgatg gtagagttat atctgctaga gaaggagcta cattagctga
     8401 aaaattatct aaaaaaggta taaagataga atatcagtat gatttaatag atagtatatg
     8461 gccagataga cctgctttat cagatagtaa agcattttta ttagatgtta aatattgtgg
     8521 agaaagtttt agctcaaaat tagctagatt aagagaaaaa atgagtgaaa aaggtacttc
     8581 tactcatgta ataactactc ttgatgatat agcatggtta ttcaatataa gaggtggaga
     8641 tgttaaatat aatccagttg tactttctta tgcagtaata actttaaaag aagtttatct
     8701 atttgttgat gaaagtaagt taaatgaaga aatactaaat gaactagcta aggaaaatgt
     8761 tcaaataaag ccatataatg atgtgtatga atttgtaaaa aatatagaca aaactgaaaa
     8821 agttttatta gatggaacta agcttagtta tacaatttac aataatatac cttgtgaagt
     8881 tgagaaagtt gatgagttca atccagtaat gttttttaaa gctcaaaaaa atgaggtaga
     8941 attagaaaat ataagaaatt cacatgtaaa agatggtgta gctttcacta aatttatgta
     9001 ctggttaaag aaaaatgtag gtaagatgga aatcactgaa ataagtgcta ctcaaaaatt
     9061 agaggactta agaagagagc aagaaggttt ctttgagcca agtttcaata caattgctgc
     9121 atataaagag catgctgcaa tgatgcacta tagtgcaact ccagagtcaa attataaatt
     9181 agaggcagaa ggattatttt tagtagattc aggtggacaa tattatgatg gaactactga
     9241 tataactagg actacagttt taggacctat aagtgatgaa ttaaaactac actttacttc
     9301 tgtagcaaga ggaatgataa atctttctaa agctaagttc ttgcatggtt gtagaggata
     9361 taacttagac atactatcta gaagttgcat gtggaatatg ggaattgatt atcaatgtgg
     9421 aactggacat ggtataggat ttgtgctaaa tgttcacgaa gctccaaatg gatttagatg
     9481 gagagtagta cctgaaagat ttgatagtgc agttcttgaa gaaggaatgg taactactaa
     9541 tgaaccaggt atatatatag aaggttctca tggtataaga acagagaatg aaattgtagt
     9601 tagaaaagct gaaaagaatt tctatggtca atttatggaa tttgaagttg ttacgttagc
     9661 tcctattgac ttagatggta tagtaccaga attaatgaat aaggatgaaa aagattattt
     9721 aaactggtat cataagttag tttatgataa aatatcacct ttcttaactg atgaagaaag
     9781 agaatggtta aaagtttaca ctagagctat atagtttgta ctagatacaa taaaaatcga
     9841 ggtattataa tgcctcgatt ttttattgta tattttatta actttaaaaa atttttaatt
     9901 tgataattct actaattttt tattcattat aagtagtata attccaaata tcaataaaaa
     9961 tgatggtatc actatgaaga cttgtaacat accaagttgg tctataatag cttgcgtata
    10021 gccagataat ttatttgctg caaatttgcc taaaaaccaa acacccatta ggaatgaaat
    10081 atacttttca ggcgaaagtt tatttaccat accatacccg actggagaaa agcaaatttc
    10141 tcctatactt tggaatgtta aaaatccaac tacccaaaat acacttgctt tgtgaattga
    10201 attagggtct gttcctgttt gtataactgc tactatcata aacaaaaatg ctatagctaa
    10261 tagtataaaa cctaagctca ttttttttgg cacacttaaa tcgccttttt tagtttgaga
    10321 taattttacc catactaaag cagagatagg tccaagaata acacaaagga gaccattgta
    10381 tgaatctatc catgaagtag gaatttgaaa attgccaaca gtaagattta tgtgttcctt
    10441 tgtatagagt gcaatagaca tagaggcttg gttatatgct atccaaaaaa atactgtgaa
    10501 aaaagctaac accaatatta ctattattct ttttttctca atcaaagtta aaggtcttga
    10561 agctagcatt ttcttatatt ctagtgattt tcttatagac tctctcccgt tactagggtc
    10621 attattcaaa ggtttataaa actttctgtt tccaaatata aagaagaata aacctattag
    10681 aaccgtaatt gatgaaaata aaaatacata tctatatcca tacatactta tagagaatcc
    10741 gcttttcata gcaaaccatt cattagcaac taaaccgcat attaaagggc caaataaggt
    10801 acctagatta gtagccatat acgtaataga gaaagctcca tcttttcttg ggtcatcatt
    10861 ggtatataag tttccaacca tagtatgtaa gtttccttta taaaaaccta ttcctaagcc
    10921 agataaaaat atcatgatgt ttatatccat cttactattt gctatgtatc ctagaaaata
    10981 accaattgaa accattagca ttccaagtat aatacagttt ttgggaccta aaaatctatc
    11041 actgacccat ccaccaataa ctggagagaa ataagtccat gctaaaaaag atgcaagcat
    11101 tgatgcggat tctgctggtg ttaaccctaa accacctttg gagacttgtt cagctaaaaa
    11161 caataataat accaatttca taccatagta tgcaagtcct acaaaggtaa atattgaaca
    11221 gcagaaatat aaatctctag gttgtttaag tttttcttgc gtttttaaaa ctgacatatg
    11281 tcgagaacct ccagataaat agtttaacaa aattttacca tactatatga gtatatgttt
    11341 ttttcatata gacgtcaact tgtaagataa tttaattaag tcgaaatata tgtaaaaata
    11401 gtatcatttt tgtgtattca gtaatatttt tttatgataa tatatgttat tattatatta
    11461 aaatacaaac atatttatgg aaaggatatg ccaatttagt agttagattg attgtttggc
    11521 aggtgggatg agctatgata agaaagaaat ctgaattaca agtagaagta aaagaaaatt
    11581 taaatggtgg tataggaaag gttaagcttg aaaacataat acaaaatgaa gagcttaaag
    11641 gaaaaggaag actatttaaa agagtagctt taccagtagg aagttcaatt ggtgtgcatg
    11701 accatacaac agattttgaa gtatattata tactaaaggg aaaaggtaaa gtatttgata
    11761 atggggaatt tgtagaagta aatgagggtg atgtagtgta tacagctgat ggcgaaaaac
    11821 attctataga aaatatagga gaagaagatc ttgagtttgt agcactagtt ttatatatgt
    11881 aaaatatgga ggaggagtca tgacaggcaa gatagaagaa attaaggaca agataaatag
    11941 attttgcaac tccaatttaa atcaagaata caaagatata agctttaaaa ttttgcaaaa
    12001 ccttttagat aataataaag agataattca ttcttctaga gctgatatat ggtcttcagc
    12061 tatactaaat atagttttag aacaaaatct tttatacaat aagaagcatc cactacatat
    12121 aacaaaaaaa gagttttcaa aacaaatagg tgtttcttta aatactataa ataataaatc
    12181 gtctttaata aaggatgttt gtagtattga ttttttaaat caagatacta tagctatttc
    12241 taatgtagaa ttttgggtaa aagagaccaa ttccaaatca aagtctgtag atttagattt
    12301 agaaaagaag aaaatactat ataaaagata tattaagcta tcacaagatg cgaatagtga
    12361 tattgaatca attagatata tggaggaagc tgtaaatata ggtaaaagta tgattactaa
    12421 agaagataaa gaacttggat tttggaaagg tttatctacc agagcctata tgatagcact
    12481 tgaatccctt gctagaaagt tagaaagtat taataatcta aaggagtcca aaaaagtatt
    12541 agaatattta atagaaatta atcctagtga tgagcaggga ataagataca aattattaaa
    12601 tgtattaatt agattaaatg atagaacttc aataaataaa ttatttgaac tttataaaga
    12661 agaaaaatct gctacatgga tgtacagtaa agctctttat tactttaaaa ataaaagtat
    12721 gtttttggca aatgattcta ttaaggttgc tagaagtaaa aataagtacg ttggattata
    12781 tttgttagat tggcgaaatg cttttggtag agaatttgtt acagaggaag aaaaggcaga
    12841 agctgtctat tactatgatg aaaacatagt gatttggaat gaagttaaag gttctatgga
    12901 ttggctatta aaaaaaatgt tggaattttc ataaaaaaaa ctactcctta cttttatata
    12961 agtaaaagga gtagttttta atttatacat ctagttttaa atcttcaggt tttattagac
    13021 ctttttttct cataaattct gaaatcaaca aagttacaat agcaggaagt ataaaattaa
    13081 gtaaaagtat accaacccac atagatatac ctccttttcc agcactttgc atagcagtta
    13141 ctgttccaaa ttgtccaacc aatccacaag tgcccatacc agaaccaata ggaatattct
    13201 ccattttgaa tattgttgta gataatggtc caagtaatat tgaagctaca gtaggtggta
    13261 tccaaatttt ccaatttttt attatattag gtacttgcaa catagatgtc ccaagacctt
    13321 gtgccacaag gccaccaact ccattttctc taaagctcat aacagcaaag cctaccattt
    13381 ggcaacaaca acctacagtt gctgccccac cagcaagacc acctaaactt aacatcatac
    13441 aaatagctgc actacttata ggtaatgtaa gagctattcc aacaagtgca gagactaaag
    13501 ctcccattat tataggttgc atagttgtag cttgcattat tatatttcca aatgaagtca
    13561 taaaagcaga aacagctgga ccaataagtt cagctacaag tactccaatt agtattgtca
    13621 cagcaggtgt aaccaatata tctatttttg tttcttttga aactaatttt ccaacctcta
    13681 cagcaaaaag tgtagcgaca aatgctccaa caggtcctcc taattcatta ccacaagctc
    13741 caacaagtgc acaagaaaat agtacaagtg gaggtgcttg aagtccatac gcaatagcca
    13801 ctgctatagc tggaccagta acctgtttag caagagggct tataacttca gtaaaaagag
    13861 aaatattgaa attatctcct aatgtattga aaattgttcc aattaaaagg gacgaaaaaa
    13921 gaccgagtgc catataactt agtgcgtcaa taagatacct ttgaacagaa atttcaatat
    13981 tttttctttt agcaaatgat ttgaaatttc tttttttata attgatttcc aatttaaaat
    14041 cctcctcata taatataagt ataatttctt tttaattaat tatataactt ttgagctgac
    14101 aagacaaatg ttatttcact aaaattagac tattgtaata gtaagaaatt aacattaatt
    14161 ttagttttaa attttaaatt tatggtttat aattagtata gggatattct gaaatataat
    14221 aattttccag tttatcccaa tatttaactt aggtagattg cttacaaaac aaatgattat
    14281 atattaggct aaaaggaagt ggatagatga tatttgtaaa aaataagaaa tacagaaaaa
    14341 ttgccataat tatatctatt cctatattgc ttgttgcgca gtactacctt tttaaatttg
    14401 gaatacttag accaatggta aagggagtag aaattgaaat tgtagatggg gaatatgtta
    14461 aagatataga taaatatgta gtaaaattaa atgaaacagt tactttgtct acaggtgaat
    14521 atattaaggt tccttcgtat gctaaaaatc caaatatttg gtttaatgta ttggataact
    14581 cagggacttt aaaaatagat ggaaataaaa tgacagcatt aaaggttggg tattcttctg
    14641 tgggtatcat gaaaaattca agagtattaa aaaaggctac tataaaagta gtagacccag
    14701 aggtagaatc actagatatg gagattaatg gggatttaaa acatgttggt gatagtgcta
    14761 ctatagaaag tacaatagaa gttgattatg ataagtttaa aaaatcatat aagccagttt
    14821 ataagagtag caatgaaaat attttaaaaa tcaaaggaaa taaagtaagt gcagttggag
    14881 ttggtaaagc tacaatatat gctaagtgtg gaaataaaga aattgagaga acatttagga
    14941 ttcaagctag agttgctgaa ataaatatgg atgatataaa aatagaagtt gaccagaatg
    15001 aaaaattgaa accagatata ataacttctc cacctggttt agaaccacca aaaatatatt
    15061 atgagttagt agattcaaaa ttacctgtag aaagagcaat aagtttaagt agtaatggaa
    15121 atgttgtagg gcttagagaa ggtaaagata gggtgagaat aacttgtgga gataaatcta
    15181 aagtaataac agtaacagta gtcaaagaaa ctataacgaa tgactatata caaaacttgg
    15241 ttggttcaca taaaatagta aacaataaag ttactattaa acttgaatgg gattatatga
    15301 aagatgtctt tgattatgat atatatctta aagataagtt gtcaggagaa tcatttaaga
    15361 aaattaaatc tataactata aatgaaagtg atttaggtaa gtctaacaag gtatatgcga
    15421 ctatagaagt agatatgaag ggtaatcaaa atatagattt tgatatttat gtcataggta
    15481 aaaaggattc agatacaact aagccaagta atgtaataaa tattaccaat ggaaatggaa
    15541 attcaaataa tgataataat attaaagata tgagggtaga aaatatatca gctaatgttg
    15601 atagagataa taatgtcatt agagttaact ggagtagtat atctcataag gactgtactt
    15661 acagtatata tgtaaaaaat aatactaatg gagatggaga atttactcta tatcaaagtg
    15721 atatacaggg aaatgagcat actataagta ttcctgaagg agatttaaat ctagatattt
    15781 atgttgttgc aaattataat ggaaatagct ctcaaaatag tgatgttata aatgtaagat
    15841 agatttgtat acaaattgaa agtgttgagt ttatttaaat attaaattaa gaaaaaggat
    15901 agtatagggt aattatacta tccttttttg ttacaatata taggtttaaa atctctagta
    15961 atataaatta taaaaagtct tatttacaca aatctataga tatttttttt attaatcaat
    16021 attgtcttaa attgaactta gtgcagcttc tattgcatgt attactgtcg tatcaaatag
    16081 tggaatagaa gtgtcatttt gtttaattaa aagacctatt tctgtacatc ctaatataac
    16141 agcctctgca ccttgtttgc caagcttatc tataatagat aagaaagctt tttttgaaga
    16201 ttcagatata attcctaagc aaagttcatt aaatattgtg tcatttacta ttatacggtc
    16261 ttcttcattt ggaattaaga cttcaattcc attattaata attacatttt tataaaaatc
    16321 ttgttccatt gtatatttag tacctaataa ggccactttt tttatttctt tttcccttaa
    16381 taccgtagca gttacatctg ctatgtgaag taatggaata tgtatacttt cttgtatttt
    16441 atctgatacc ttatgcatag tattagtaca gataacaata aaatctgccc ctgcctcttg
    16501 taatttaatt gcagcatcag ctaaaatttt ggcgcttttt tcccaatttc cactagattg
    16561 gcattcttca atttcttgaa aatctacact gtaaagtata catttagaag agtgtagtcc
    16621 acctaatctt tcttttatta ctgtattaat aacttgataa tatgtaatgg tactttccca
    16681 actcatacca ccaattaagc ctatagtctt catattatac ctctcttatt tatttatttt
    16741 gaaatagcta tttacaaata caagtatagc atctaaaata gaagcataca ataataaaat
    16801 tgtatggagt acaattataa ttaagaggag taattatatg ccaataaatt cttttgaaaa
    16861 ctatcctatg acatggaaac caaagttaga taaccgaaaa ccaccaatat ataaaacttt
    16921 agcaatgtta ttagaagaag atattaaaag aggaaattta aatcctggag ataaattgcc
    16981 tccacaacgg gaattagcag attttctaga tttaaactta agtacaataa cacgagcatt
    17041 taaactttgc gaagaaaagg gactaatatg tgcaaaagtg ggaaagggaa cattcatttc
    17101 ttctgatgta aatgtaagta atacattatt atatcaaacg gaatcaaaag acataattga
    17161 gttggggaca gttcatcctc cgtatgagca aaatacatat attattgact ttattaaaaa
    17221 tgtactaaaa caaccagaaa tggataggtt tttacaatac atgtctccat ctggcacata
    17281 tatgcaaaaa aagtcaattg caaaatggat agaaagaaat aatgtataca ccagtgaaga
    17341 aaatatatta ttatctacag gagggcaaaa tgctatatgt gcaactttac taggattatt
    17401 taaagctggt gatagaattg ctacagattc tttaagtttt tctggaatta agtcaatagc
    17461 taaaatgata ggtattcaat tagtcccaat tcctcaagaa aataatgaaa tatcgattga
    17521 atatcttgaa agttattgta aaaatgaaaa tataaaaggc atatatctta taccagatta
    17581 tcataatcca acgacacata ctatgtctga tttatctcgt aaaaagatag ccaagatagc
    17641 aaagcaatat aatataataa ttattgaaga tgctataaat agcattttta gagatggtat
    17701 acaaactccc atattttctt tagctagtga taatactata tatattttta gtacatctaa
    17761 atttttatgt gctggtctta gagtagcatt tgtagttgct ccaaaacgat atatagaaaa
    17821 tttagaaaat gcactatata atatgaatct aatggtttct ccatttacag cagaaatagt
    17881 acaccgttta ttatattctc ctattataga taaaattata gaagagaaaa gagatgcaat
    17941 tatagaaaga aatgaagttg ctgataaagt tttgtcagat tataatttga ttggtgataa
    18001 gaattgcagt tttcgttggt tacttcttcc tgatgaattg gatggaaaat catttgaaat
    18061 ttctgcaaaa aatctaggag ttcaagtata ttgtgctgaa cgattttcag taggaaactc
    18121 tacagttcca aaagcagttc gtatttgtgt aacagctcca aaagatgtag aagaattaga
    18181 aaaagggctt aatataataa agtcacttct taagagttaa atttatttta ctattattta
    18241 attaaataaa taaaaaggcg gagaaattta ttataataaa cctccgcttt tattatttaa
    18301 tgaaatactt tactttttat taaaaaattt aattttaata atcttgaaaa tataatcgtt
    18361 ttatggtaaa ataattctta aaaatagaaa aaattaatca tttgttaaaa aaaatgcata
    18421 atttattgta atttattgac gaaggttgaa aaatattcat aaatgtgcga aataacagaa
    18481 aaaatgcaaa aattaattca atttcatttg ttataaaatc tatatggcaa aattaaatct
    18541 gcctatcaga atgatataaa cacatcagaa aggaggacgc tatcaaataa tacaagtagt
    18601 taactttgat agcaaaaaat tatgaatgaa caaactagaa tatccttaga gagagctgct
    18661 gaattaaaat caaaaattga tgattatatt caggctagaa aaacgattaa cagaggtctt
    18721 gaaaaagaag aagagataaa taaacgaaaa cagaaaatat taagtatctt aaatggaact
    18781 gaagaggatt ggaataacta caaatggcaa ttatcaaata gaataacaga tgtagatact
    18841 ttatcaaaaa ttataactct aactaaaaaa gaaaaagaat atataaaaga ggttggtact
    18901 caatttagat gggcaatatc tccatattat ttgagtctta tagacccaga agatatatgt
    18961 gacccaataa aattactgtc tataccaaca catatagagt tggaagatga acaagaagat
    19021 ttggacccaa tgggagaaga gtatacaaac ccagcaggat gtataactag aagatacccg
    19081 gatagattaa taataaatgt aacaaatgag tgtgctatgt attgtagaca ctgtcagaga
    19141 agaagaaata ttggacaaca agattctcat aagtcaaaag ctattatcca agaatctata
    19201 gactatatca gagaaaatga agaaataaga gatgtactag taactggtgg agatgctctt
    19261 acattaaaag atgattattt agagtggatt cttagccaac ttaaagagat accacatgtt
    19321 gattatgtta gattaggtac taggactctt gttacaatgc cacaaagaat tacagatgaa
    19381 ttttgcaata tgctaaaaaa atatcaccct gtatatataa atactcattt taatcatcca
    19441 atggaaataa ctaaggaatc taaagaagct tgtgaaaagt tagcaaatgc aggagttcca
    19501 ttaggaaatc aggcagtatt attaaatgga ataaataatg ataaatttgt aatgagatgt
    19561 ttaaatcaag aattactgaa aataagagta aaaccttatt atatattcca aagtaaacat
    19621 gtaaagggaa caaaacattt caatacatca gtagatgatg gtcttgaaat catggagtat
    19681 ttaagaggat atacatcagg aatggctata ccaacatata tagtaaatgc tccaaaagga
    19741 ggaggaaaga ctcctttgct tcctcaatac cttgtatcaa aaggaacaga ttacgttatg
    19801 cttagaacat gggaaggaaa agttataaaa atggaagatg aacctgctgt agatataaag
    19861 aaacttataa aagaacaagc acaggattaa aaaaatattt aaagtttata aaaagaaaca
    19921 actttaaaat aaaaagaaaa tggatgtcaa atttatatca atttgcatcc attttttatt
    19981 agttatttat tattttgttg ttgattaact aattcaagat atccacttgg gtggaagtaa
    20041 tatatctcag aagtattttc atttacaaag taaccaatat caccatctgc atctggtaaa
    20101 aatacataac cattaagatt tttagctttt aatgcttcaa aatcactagc atttccttga
    20161 tatatgtaat caacttcatt gttgtatttt actaaaagtt ctttagcttg ttcttgagtc
    20221 aatttagtat tttggcttac aggaacattc ttttgagaat ctgcataaga agattcattt
    20281 actggtgcag ttaataacaa acaagataaa actaataaag atataagtgc ttttttcata
    20341 ctaaaaccct ctttcatgtt taattatata agattcatta cttaataata ttgtatgttt
    20401 cctataatta aatattacca ttaaagagaa taatattaca gttacacagc tgtaactttt
    20461 gattacaaaa tcgtaattaa attgtatttt tattccattt gtattttatc atgtctacga
    20521 tttacaaact cacagaagta tatctttata acgcccatca caggagcaga tagaatcata
    20581 ccaggtatac caaagaatcc tccaccaaca gtaactgcta ggattgtaaa gaatgggcta
    20641 agacctagtt gtccacctac gatttttggc tctataaatg taacttcaac ttgttgaatt
    20701 attattaagt aaattaaaga agttaaagca attgttggat tggagaataa attaattatt
    20761 acaactggtg ccatacctat tactggacca aaatatggaa ccatattcat gacacccata
    20821 agtgtaccaa ataatagtgc atattcagat tttaaaaagt aaagaccaat tccagaaagt
    20881 actccaacta taaaagaatc taaaatctta cctgtaaagt atttaccaat atttaaattt
    20941 aagctttgac atagttctat tataaagtct ccatattttt tacctaagga aatataaact
    21001 actttttttg taaacagtaa gaatttttct ttttctaata atatatagaa acaaattata
    21061 aaacctaaaa gaaattgtac tataaatttt ccaactgaaa atgtagtgct aaatatccca
    21121 ccaagtgaac caataagcaa gttactaaat ttaggcatta cactcataat tttgtcacca
    21181 tactctttta atgtattagg gtcaactgat tgtaaactct tacctaagtc gaataagaat
    21241 tgctctgttt tatctatgta tgtaggaatt tgagcaacta aatcagctaa actatttact
    21301 atggatggaa ctgtaaataa tataaaggaa attagtataa ctatgagtac accataagta
    21361 agaagtaacg aatatattct cttaaaattt aatttgcttt ctaagaactt tactagtggg
    21421 ttgaatatat atgctaatac aaatgctatt ataaatggtg ttagtagtga cattaataaa
    21481 cttatcactc caaaaaaata tttgtaatta tcaataactt taatcaagat atatgaaaca
    21541 actacagtga gtacaatatt tagataaatt tttttatctt gcaaaataac acaacctttc
    21601 ttatatttat taaatttaga tatacttaaa tctaagttaa agttaatatt tatagcttat
    21661 tatacaataa aaagcagtat taatatagta tgattaatat gaaattataa atacgttaaa
    21721 actttatgtt tatagctaaa ataataaaaa ttatttatat tgtgtttata tataatctaa
    21781 aatgaaaaaa agtggtgcct ttgattaaac taagttttta taatttaaat tttgtacaat
    21841 aagctatctt ttattattct ttaaaatata tatttcattt aattatgaca aataaagata
    21901 aaaattaaat attttagagg tgattttatt tatatataga attttagaat aatactatac
    21961 aaatgtattg tattattatt tttatatcaa aaatagtaat aaagtctata tacatttaga
    22021 aaatactgtt taaaaggagt aggatttatg ataaaaaaag agatatctaa ctttagagga
    22081 agtagtgatt atgtagtatc accagaattg atggcatcag ttaatgttgc tattgctctt
    22141 gaaaagccac ttttgattaa gggcgaacct ggaacaggta aaactatgct agcacaagca
    22201 atttcaaatg aattaaaaaa agatttagta atttggaata taaaatcaac tacaaaagca
    22261 caagaagggc tttatgtata tgatactgtt caaagacttt atgatagcca atttggagga
    22321 gaaggtgtag atgatattag caagtacata aaatatggta aactaggaga ggcctttagc
    22381 tcaaatcaac aagtaattct tttaatagat gaaatagata aggcggattt agaatttcca
    22441 aatgacttgc tttgggaatt ggataaaatg gagttttaca taaatgagac aaaagaaact
    22501 gtaagagcta aacaaagacc aatagttatt ataacttcaa atgcggaaaa agaacttcca
    22561 gatgcttttt taagaagatg catatttcat tatatagaat ttcctgatag agacatgatg
    22621 gaagaaatag ttaaagtaca ttttgataaa gtagaagaac acctattgga acaagtaatg
    22681 actacttttt attggattag aagtttaaag gacatacaaa aaaagcctag tacatcagag
    22741 ttaatagact ggatacaagc attaactttg agtggaatgc ctattgaaaa aatagaaaaa
    22801 gaagttcctt ttgcaggaat actacttaag aataatgagg atattgaatc tatgcaaaga
    22861 cacttatagt taataggagc tggataatta tgtttattga atttttttat ttattgaggt
    22921 caagaggatt aaatgtatct ttaaatgaat ggatgacttt aattgaagca ttggataaag
    22981 gactgtgcta ttcaaacttt tcaaattttt actatctttg caggatgatt ttaataaaaa
    23041 gtgaaagtga ttttgataag tttgatgcag tgtttttgga gtattttaaa ggtatagaac
    23101 accaagaaga aattccagaa gagattatga attggcttaa aaaaccagat atagatttag
    23161 aagagtttga aagattagaa caaaatccaa atataaatct tgataaatta agagctaaat
    23221 tggaggaacg aataaaagaa caagattctc ctcataatgg tggtaattat tggataggca
    23281 caggaggcac ttcagagtta ggacattcag gaaaagggca aactggtata cgtataggtg
    23341 gaaattctac ttatggtaga gctgttcttg aagttgcagg agaaagaaaa tacagagatt
    23401 ttagagatga tgaagtttta aatatgcgtc aatttcaagt tgcactaaag agacttcgtc
    23461 aattttctac tagaatagat gctccaaaga cagagcttga tttggataag actattgaag
    23521 agacttgtaa taatgcagga tatttaaagt tattttttga gaagccaaga aaaaatacag
    23581 tgaagctttt attgcttatg gattcaggtg gttcaatgag agggtatagc actttatgta
    23641 atacattatt tcagtctgta agtaaatcaa atcattttaa agatgtaaag atatattatt
    23701 tccataactg tatttatgat agattattta caacacctga atgttggtta agtaaatcta
    23761 ttaatactga atggatatta aaaaatatag ataaaaacta taaagttata attgttggag
    23821 atgcttctat gtcgccttct gagttgcttc atattggtgg taactatcgt ggtccatata
    23881 attacacacc tggtatagag tggcttaaaa ggtttaagag aaagtacagt aaaattgtat
    23941 ggatgaatcc agaacttaga gatggatggg attcaattaa ttattggtat caaactcaaa
    24001 gaatgataca aagtgaattt aatatgtttc cattgactgt aaaaggtctt gagaaagcat
    24061 tgaaaaattt aatggtttca agataaagta aatataaatg atggtatgat ttattcaaaa
    24121 ttgtaccatc attatttatt tttttaatat atctattata aattgtataa ctgaaactta
    24181 aaaaattata tagtctaata cattttagac tcacacaaaa catatacatt aataataatt
    24241 ttagaagtcg aggtgattat aataaattat gaattaattg taaaatacaa tggagatata
    24301 ttgaggttag aagaagaatt aggtgtatca gtagagatac ttaattcatc atatgcaata
    24361 ataacatcaa gtaatgaaga agatgtaaat atacttttaa cttatccaga aattgaattt
    24421 atagaaaagc cttttatatt acagactcag gatgtgcaaa gtttttcaag tacaggaata
    24481 acaggattta aaaatagaac tggtttaact ggaaaaggaa ctataattgg tataattgat
    24541 tcgggaatag attatactct acctgtgttt agagatagtg atggaaggtc taagatatta
    24601 tattattggg accaatctat tcaaggaaat ccaccagaag gttttagaga aggaacatta
    24661 tatactaatg aagatataaa taatgcaata gatggaagta tgtatatacc tatttcaaca
    24721 actagcttac atgggacaca tgttgcaggt atttgtgcaa ctattgcaag tgatgccaga
    24781 ataatagtgg ttagagttgg aaatatacag accgatattt tttcgagaag tacagagttt
    24841 atgagggcaa ttaaatttat tttagatagg gcattagaat taagaatgcc tgttacatta
    24901 aatataagtt atggaagtaa tgaaggttca catagaggaa catctttatt tgaacaatat
    24961 atagatgata tgtgtttatt ttggaaaaac aatatagttg tagcagctgg aaataatgca
    25021 gataaaggag gtcataaaag gattaggctt caaaataata ttacagaaga agttgagttt
    25081 atagttgggg aaggagagcg tatattaaac ataaatatat ggccagattt tgttgatgat
    25141 tttagtgtac atttggtaaa cccatcaaat aatcaaacac aagcaatctc tctaacttca
    25201 ggtgagataa ggaatacttt gggtgaaact agaataactg gttattttta ccctatagca
    25261 ccgtattctc tcacaagaag agttactcta caattaagtt caaatacaca gataactcct
    25321 gggttatgga aaattgtatt tgaaccaata gatatagtaa ctggtaatgt aaatatatat
    25381 ttgccaactt ctgaaggtct aaatagaaat actagatttc tgattcctac tcaagagctt
    25441 actgtaacag ttcctggaac agcaagtaga gttataacag taggtagttt taattcaaga
    25501 acagatatag tatctatatt ttctggtgaa ggagatacac aattaggtgt ttttaaacct
    25561 gatttattag ctccaggtga agatatagta tcttttttac caggaggtac aagtggagca
    25621 ttaactggaa ctagcatggc tacacctcat gttacagggg tttgttcatt gtttatggaa
    25681 tggggaattg taaatggaaa tgatttattt ttgtattcac agaaattaag ggcattactt
    25741 ctaaagggag caaggagatt aagtaatcaa tcttatccaa ataattcatc aggatttggt
    25801 tttttaaatt tatcagatat agatttgtac actctatcta atataaatca agatttagaa
    25861 acagaggata tgggatatag aagtattaat aagtcattta aagatgagga aaatagttat
    25921 aagtttatag atggttataa tatgcaaata cataatgact tagagaatga aatttatata
    25981 agtaaaaatg caagtagaca atcaggaata ctatcaggaa tagatatagt ccatactcct
    26041 gaatttgaag aagaactagc tgggttaggt atgagtcaaa ggttttttaa gataagtgat
    26101 tcattaggtg tactatctat aaataataca gactatagta gtatacaacg agttttgcaa
    26161 cttccttcaa tcataagaac tgtatcgact acaaagatga cattacttgg agaaattaat
    26221 cgaggtactt ttggaggtgt agttgcaaca gaagaaatgg gcgtaaattt ctttaaaaat
    26281 aatcctaata ttaatataac aggaagaggg actctaatat caattgcaga tacaggaata
    26341 gactatctac acccagattt tatttatcca gatggcactt caaaaatagt atatttatgg
    26401 gaccaaacaa aagaaggaac tcctcctgat ggtttttata ttgggacaga atatacacga
    26461 gaagatataa atcgagctat cgcagaaaat gaccctagtc tatctcagga tgaagttggt
    26521 caaggaacta tgttgagtgg gatatgtgca gggcttggaa atgtaaatag tgaatatgca
    26581 ggtatagcag aagattctga gctaataata ataaaactcg gcaagataga tgatttttat
    26641 aatagtgcaa tgttgtttgc tgcatctcag tatgcatata aaaaagcttt tgaacttgga
    26701 agaccattag ttataaatat gtctttaggt accagtagcc tagcaggttt aaccaatagg
    26761 agtaatagtg aaaaagcgtt ctttactaga gggttatgta taacggcagg agcaggaaat
    26821 gagggtaata cacagacaca tacatctgga ataataccat atgttggagg ttctgttgaa
    26881 gttgaattag agttaaatga agacgaggaa gaattatcat tagaactttg gttaaataga
    26941 ccagataaag ctgatgtaat aatagtatct cccactggtg aagaaagtaa aagtgttgga
    27001 atttcaaatt ataataaagt aacaggctta tttgatttag aggggactga atattctata
    27061 acatatatat acccaacaac tttttctgga cagcaattta ctaatgttac tttaaagaat
    27121 gcaaaaagag gtgtatggaa gattcgatta gtaggagttt atattataac aggaagatat
    27181 aacttatacc ttccaaatag agaactttta aaaagtggaa ctagatttag agaggtagac
    27241 cctttttaca ctataaatta tcctgcgatt caagatgatt taataaccat aggagcctac
    27301 aatactatta atggtagttt atggcaaagt tcatcaagag ggccaactat tgaagacagg
    27361 ttaaaaccag atatagtagc accaggtgtt aatataatag ctgcttatcc tgggaacacg
    27421 tatgcaacta taactggtac agcagcagca agtgcacatg cagctggtgc tgctgcaatg
    27481 tattttcaat atacttttgt tgacggtaga tatccaaacc aagcatatgt gcaaaaaata
    27541 aaaactttta tgcaagctgg tgctagaaaa gattcaaaca cagtatatcc aaatacaaat
    27601 tctggatatg ggctcttgga tgttagagga atgtttgatg ttttaagata ggagggattt
    27661 atggaaaaat cttattgtat aatttatcaa ggtgatatag aatctgccct acaagaaaat
    27721 ggaataaata ggtatatggt tttaaatagt cagcttgcag taatatatgt acctttagat
    27781 tttgatgaaa ctattttaaa taatataata caagttgctt ggtgggaaga atctgaacca
    27841 atgagcagtc taattgaaat aactaataat gtaaataatg gagaaaccat tacaacagca
    27901 gctgaaactg attatattta tgaaaatcca tataatgata taacagggag aggaatttta
    27961 ttagcagtta tagattctgg gatagattat ttgcatcctg attttataaa tgatgatgga
    28021 actagtaaag ttttatattt atgggaccaa gaagcaaata caaatccacc tccagaaggt
    28081 tttatttttg gaagtgaatt tacaagaagt gagttaaata tagccataaa tagaaatgat
    28141 gggagtttga gtcaagataa tataggtact ggaactttag tttctggtat attagttgga
    28201 aatggaagga taaattctca gtacagaggt attactacag aatcagactt aatagtagtt
    28261 aaattaaaat catatacaga tacttattat gctggaagga taaattacag tgtttcagat
    28321 tttttagcag ctataacgta tgttactaac atagcaagaa cagaaaataa accactgata
    28381 ataaatttga ctattggagt taagtcaagt gctgtagcaa ctacttcaat actagatact
    28441 tttaatatat tgagtagtgc tggtgtggta gtagtgagtg gtgcaggaaa tcaagggaat
    28501 acagatattc attattctgg cagatttagc agtgtgggag aagttcaaga tgtaataata
    28561 caagatggag atgactatgc tcttgatata acactaaata cgaatggtcc agataaagtg
    28621 ggagcacaga taatatctcc ttcaggtgaa gttagtcatg atataaggta ttctccagac
    28681 ttttatatat atagaggaaa atttaactta gaaaatacta cttatgcaat gagatttatt
    28741 tatccatata ttacctctgg aaaagaaaat ttggagataa gattaagaga tataaaacct
    28801 ggagtatgga ttttaagatt gacttcagaa cttataataa atggagaata tgacatatac
    28861 ttgccaaata aaaatttgat agctccagac acaaggtttt tagaacctga ttcagtagct
    28921 actataacta tgtatgctgc tagtgatgat gtaattacag ttggtacatt taacaataag
    28981 actgatagta tgtggattgg ttcttcgaaa ggaccaatta gaggaagagg aattaagcca
    29041 gatatagtag cttcaggtgt agatataata tccacatata aaaatggaac atataataca
    29101 ggaacaggaa caggagtgag cagttctata gtcacaggtg ttttagcctt attgatggaa
    29161 tacttagaaa aacaggataa tgtaccgaga ttatcattgt ttacacaagt tttaaaaaca
    29221 tatttaatat tgggtgctac aaaacttgag atatatacat atccaaatgt atcgcaggga
    29281 tatgggattt taaatttaaa aaatacgatt caacagatag caaatactct atagataaga
    29341 acctatgtaa aattataatt gattattagt ttaattgtat caaatacttt agatagagta
    29401 gaaaaatagc ataaaaaata aatatgaaaa ttaaaaaata gttttatatt ttgaatacac
    29461 aaagtaaata ttttgtatat aaataggtat aaattaagta ttgaaaagat atgatgttaa
    29521 tttaaaaatc attataattt agacttatga attttatttg taaaattgct aaaactatta
    29581 caaaataaat aatagaggtg atagttttgg aaagtaaaaa ggcaagagca ttaaaaggta
    29641 aagataataa aagacttaaa agttcacttt tagttggaaa tgagtcgaca gcagcatggg
    29701 ctgatgttga aaaattaaaa cctcatagta aagtttcaat accttcaatt aagggtgtcg
    29761 aagaagcaaa agactgggtt gacaatggaa gtaaattata aaattttgga aattgaagta
    29821 ataaagaagt aatgaagata agtatttatt atcattatgt aaggtagaat tattatattt
    29881 taaataacaa tcagtatcaa ttatataaat ttattgacta aaaatttata aattggtata
    29941 attttgttaa ttagcagaaa taataaaaga taaatactgt gaagagaaga gtagatataa
    30001 aatgtagttc tagcgagttg aggatggtga aagctcaata cgaggtttat attgaagaac
    30061 atcttggagt ttctaatcga aagcttattt agtaagtaga cttagacgga aggcaccgtt
    30121 ataggcttta agcattgctt aactaagagg tcattatgac aactagggtg gtaccgcgag
    30181 agtaatagtc tttcgtccct ttatataggg atgaagggct ttttttattg aaattatatt
    30241 taaaagaaat taataacaat tatactagga ggatttaaaa tgcaaaagga atttataaca
    30301 gtaaaagaat tgtacagaga aaaagaacag tacataggga agactgtaaa agtagctgga
    30361 tggataagaa catctagagt atctaaaaat tttggattta tagagctaaa tgatggaagc
    30421 ttctttaaaa atatgcagat agtatttgat gagaaagtag aaaattttaa agaggtagga
    30481 aaattagcaa taagctcatc tatacttgta gagggagagt tagtatctac agaaggggct
    30541 aaacaaccag tcgaaataca tgcaaaaagc atagttgtag aaggggaatc agatagttcg
    30601 tatccactac aaaagaagag acatacgctt gaatatttaa gaacgatagc acatttaaga
    30661 ccaagaagta atactttttc agctgtattt agagtaagat caatagctgc ctatgcaata
    30721 cacaaattct tccaagaaag aaactttgta tatgcacatt ctccaatcat aacaggtagt
    30781 gactgtgaag gtgcaggaga gatgtttaga ataacaacta tggatttaaa tgatattcca
    30841 aaaactgaag atggcaaaat agactatact caagatttct ttggaaaaga ggctaattta
    30901 acagttagtg gtcaattaaa tgccgagata atggcacttt cttttagaaa cgtttatact
    30961 tttggaccta catttagagc tgaaaactct tatacaggaa gacatgcttc agaattttgg
    31021 atgatagagc cagaaatagt ttttgcagac cttgaagata acatggaact tgcagaagat
    31081 atgataaaat atgttataag ctatgtatta gaaaatgctc ctgaagaaat ggaatttttt
    31141 aatagtttta tagataaagg attgttagaa aggttaaata agatagtaaa ctctgagttt
    31201 attagaataa cgtatactaa agcagtggaa ttattaattg aatctgggca tgaatttgag
    31261 tatcctgttg agtggggatg tgaccttcaa actgagcatg aaagatatat aacggagcaa
    31321 atatataatt gtccagtgtt tgttacagat tatccaaaag atataaaagc tttctatatg
    31381 agaatgaatg aagatggtaa aactgttaga gcaatggatt tactagttcc tggagttgga
    31441 gaaatcgtag gaggttctca aagagaagaa agagaagatg tattgttaga tagaattaat
    31501 gaaatgggat taagagaaga agattattgg tggtatttag aacttagaaa gtttggtact
    31561 gctactcact ctggatttgg tcttggattt gaaagaataa ttatgtatat gacaggtatg
    31621 tctaacataa gagacgttat acctttccca agaactccta aaaatgctga attttaataa
    31681 ttatatataa taaaacttat ataactttaa gtataaacac taaaatgact tgcatattta
    31741 tctattttag agatatgcaa gttattttta ttgtactata aatatataat ttgattactt
    31801 ttattttgcg atataatact tataggttta tgtaatagta tgtaaccttt taataaaatg
    31861 caacacaatt acgtccttgt tcttttgcag tatatagagc cttatcacaa ttacttataa
    31921 actcatttaa tgttattgtc tttccaattt tctttgtata aactccaata ctaacagtta
    31981 cacattttaa aggaacatca tcacgctcaa aattgcagga ctctataatt tttcgtaaac
    32041 attctgattt aagtttagca tctgcctcat tacagttaaa aatacatata aaaaattcct
    32101 caccaccata tcgtatagca tgttcatttt cagaacttgt aaaatctaaa attactttgg
    32161 caatattttg tagacaatag tctccctttt gatgtccata attatcatta aattgtttaa
    32221 aataatctat atctatcatc attccagtta taggttcttg atttgcatga ctgattaatt
    32281 ttttttgtag aatatcttca aggtatctac ggttgttcat tttagtaagg tcatctgtca
    32341 taactttgtc gttaagtaaa ttatttatat gagatatttc ttcatattgt tgactaatta
    32401 aaagtttatc atagtaggta aatacacgat ttctatatag cattgtagaa acaaaaatgg
    32461 caagggatgt tataaaaaat gtgttgacaa tattactaaa ctcattgcct ggtatagttt
    32521 gaatcccagg taagaataaa ttaagaaaca aaaagcatcc tccaaaaact attactgatt
    32581 ctccaaattt taatactgag aaagctgcag ctgctaacat aatataacta aatacactta
    32641 ggtcatttcc acctaactgg tcaagtagag taattacaca accccatagg cagaaaaaag
    32701 tcacataaat tatccataaa tttatataaa acgtacagca atcctttttt ttattccaaa
    32761 gataagaaaa tacaaacata aagacagaag atacacaaaa tagtgttaca tacatataaa
    32821 aataccattg gcgtcttggt gtgacaaaag ggcctccttc tctagctgag attgatatca
    32881 tcataattat ttgagatatt actattatta tgcaaatgat tttacccgta tgataaagat
    32941 aattgcagag ttctttctca acattgtctt tgtgtttttt gtctagagga aatccaaaaa
    33001 atttttttat tttttctaag ttcatataag cctccattaa aaataaagca taaaaataag
    33061 tattcctttc tatcattaga tatttggaat acttcgttta tgatttaatt atatcaaaat
    33121 atattgtgtg taacaatcta aaattgtgat agataaaatt tattagataa tgtcgagtaa
    33181 ctttattgat taatacttta ttataattaa gatttacaga tagtttacta ctgaaaataa
    33241 agaatagaat aaattcaaat taagcataat aaaatataaa taataaagtt cgcattaaca
    33301 aactatttaa atatcaagac ctgttaaaaa acaacagcaa taaacaaata aaatagataa
    33361 atatatccaa ttaaggtata attaagtttt atatgatata gttatatttg ataatttaca
    33421 atagtaaaac ttggagggaa aaaatgggtg aaaagaaaat aaataatatg aattattcac
    33481 ataataatta ttccaaaaag acaggtgaac caactagaaa aataaaaaat agccatatca
    33541 ctcttaaaag taaagaagaa aaaatttgtt ctagttgcaa taaagaaaat aatactaagg
    33601 ataattactg taaattttgt ggaaatgaac tttatgaaat agcatcatta agaccacttg
    33661 aaacaaaact agacttgaaa tctaaaataa aagagctttc atatcatgca aataaaagag
    33721 gtgtattttt aacaacattt acaaccatat ttatattgtt tattattgca ttgatattta
    33781 aagctattat aactattcaa tttaatgata ttagttattt agtaaatcca gcacatataa
    33841 tcctagctct caacttgggt caaattagtg tatctatgtc taccatgatg ggttctgggt
    33901 ttataaatgc caatataggt ttgttgatat tacttataat ccctattttg gtattattaa
    33961 tatcaaacct aatttttatg agaaaaagat gtagagattc aaaaactgta ttagcaaatt
    34021 ctctaggagt tggaattttt tatggattag ttttagctat tttatctatt tttactaatg
    34081 taaaaactag ttcacatagt atgttagaat atggatatgc attagaatat agttatgaat
    34141 tttttagtgt tcttttaaat ggattcgtat tagggtttat atgtacatac ataactactt
    34201 ataaaaaaag ttatgaaaaa gaaaatatgt atttatctct tttttcaaat tctataagaa
    34261 cattcatatt aggttatgtt ttagtattag taatactatt ggtactaact atatctgata
    34321 gtagttactt aaatgaacta gatatgagta gttattcaaa tggattaaat ttatttacta
    34381 tactcccaca aatagctagt tatatgtggg cttttgcaaa tggaatttca gtaaccataa
    34441 taaactcaac agtatcaatg tttactttaa gttcttcatc tttatttgga gatactaaat
    34501 taatgtttta tgcaatggga gcattgtcta tgttaatatt attattaaat ggatacaagc
    34561 taagatttaa gtataataca gatagtataa gacctataat agtatttagt atatattatg
    34621 catttttgat gggaatattg gctttattta gtacatttat actagatagt aatattaatt
    34681 tctttaatac aactaattat ggaacaactt taataatgca atttaaagtc ttacaagcta
    34741 ttgtaatttc atttgtatat agttttgtga tatctttaat aggatataag ctaaattcag
    34801 ctgattaaat atgattggag ggaatttctg tggaaggaaa tactaataat aaagtagatg
    34861 ataaattttc taaggttaag aaaaagtttg gtagtggaaa atttaaagtt gaattatata
    34921 aagaaaaatc aaaattaaat agagagattg atgatattca agaaaagaaa gcaaagatat
    34981 tcttggaaat gggaatactg acatatcaaa aaattagaga agattctatt aatgataata
    35041 gttttgataa attctgtgat gagttactag aacttgataa gttaatttat gaaaaaaata
    35101 tggaaattaa tgaaatggaa atggcagaaa gtaatgtaac ttgtgagtgt ggttatgttg
    35161 gaaatgtaaa tgataaatat tgtgctgaat gtggtaaaaa atttgaattg gaaaatgaat
    35221 gtgatgattt tataatttgt ggttattgtg aaagtgagat agatacagag gctgaatttt
    35281 gtccatgctg tggaagaaaa attataatgg atttagaata atattgggaa acctatgtat
    35341 agtatacatg ggttttttta ttgaaattat ttaaatggac ttataacagt agttatataa
    35401 aatgaaaata aacaccaaaa aaatgaaata aaatttcttt taaatgtaaa aaacaagcta
    35461 atatataaaa taaatcagta aaaatataga tgcgagaaaa aaatatgaaa aaatattgca
    35521 aagaaaaagt tttcatgtta ttattaatac ataaatcaag aaaataaatt tcagaaacga
    35581 ggtaatttaa aaaatgctag ataaggtaaa gggaagatta atagtatcat gccaagcttt
    35641 agaagatgaa cctcttcata gtccttttat aatggggaga atggctaagg ctgctatgga
    35701 aggtggagct gttggaatta gagctcaagg agttgaagat attattgaaa taaaaaaagt
    35761 tactggactt cctgttatag gtattataaa gagaaactat gaagattcag atatatatat
    35821 aacgccaact aaaaaagaag ttgatgaact tttaacaaca gggtgtgaaa tgatagcatt
    35881 agatgctacc aatagagtta gaccaaataa tgaagactta aaagaactta taaagtatat
    35941 aaaagaaaac ggtgttctag taatggcaga tatttcaaat tatgatgagg ctatcaaagc
    36001 acaagagtac ggtgtagatt gcgtttcaac tacactatct ggatatactc catatactaa
    36061 aacattagaa ggtccagatt ttgtattaat ggaaagatta gttaaagatt tagaaatacc
    36121 tgtaatagct gaaggaaagg taaatactcc tcaagattta aaaaaggtct ttgagttggg
    36181 tgttcattca tcagtagtag gttcagcaat aacaagacca caattaataa cagaaaaatt
    36241 tgttaaagca attgaaatta attaaaaatt aatttataaa ttaaaaaatt attatattta
    36301 actatatttg aaaattaaaa ttggaggtaa agatatgaga acaacagata tgaagggaat
    36361 ttattcagca ttattagttt catttgataa ggaaggaaat ataaatgaaa aagggttaag
    36421 acaaataatt agacacaata tagatgtttg taaagtagat ggtctttatg taggaggaag
    36481 tacaggggaa aacttcatgc tttcaactga tgaaaagaaa agaatatttg aaatagctaa
    36541 agatgaagtg aaagaagaaa taaaattaat agctcaagtt ggttcagtta atttaaaaga
    36601 agctgtagaa cttgctaaat ttacaactga tttaggatat gatgcaataa gtgctgttac
    36661 acctttttac tataaatttg attttgaaga aataaaacac tattataata caataataaa
    36721 ttctgtagat aatagattaa taatatactc tataccattt ttaactggtg ttgatatgag
    36781 tttagaccag tttggagaat tatttgaaaa tgaaaaaata ataggtgtta agtttacagc
    36841 agcagatttc tacttattag agagaatgag aaaaacattc ccaaataaat taatatttgc
    36901 aggatttgat gaaatgatgt taccagctac agttttaggt gtagatgggg caattggttc
    36961 tacattcaat gtaaacggtg tcagagctag acaaatattc gaattaacta agaatgaaaa
    37021 aatatcagaa gcacttgaag tacaacatgt gactaatgat ttaataacag atatattagg
    37081 aaatggctta tatcaaacaa ttaaattact acttgaagaa caaggtgttg aggctggata
    37141 ctgtagacaa cctatgaaag aagcaactga tgaaatgaaa tcaagagcaa aagaaatata
    37201 cagaaagtat ttttaataaa atacttttag tatgggagga ttagtcaaat ggtaggattt
    37261 acttggatag attttgcaat actagtggtt tacttattgg cagttttatt tgcaggattg
    37321 ttattttcaa aaaaggaaat gaagggaaaa gagttcttca aaggtgatgg aactattccg
    37381 tggtgggtta catcagtatc aatatttgcc acattattaa gtccaatatc atttttatca
    37441 ttagcaggaa attcttatgg tggtacttgg attttgtggt ttgcacaatt aggtatgttt
    37501 atagcaatac ctttgacaat aaaatttttc ttacctctat atagtaggtt agaaatagat
    37561 acagcatatg aatacttaga aatgagatac gaaagcaaag gtcttagagt acttggagct
    37621 ttgatgttta taatatatca aataggacgt atgtctatca taatgtatct tccatcaata
    37681 gttctggctg gtcttacagg aatacctgta aatgtactga taatagttat gggtgtaata
    37741 gcaataattt actcatatac aggtggatta aaggctgtct tgtggaccga ttttatacaa
    37801 ggaatggtat taatagtagg tgttacaggg acattgttct atttaatagc aagtataaat
    37861 ggtggttttg gaacagtaat ggatactctt acaactggac acaagttctt agcaagtaat
    37921 gaagttatgt ttgataaaaa tatactatct acaagtgcat ttataatatt tgttggagct
    37981 ggtcttaata ctttttcatc atatgtatcg agtcaagata tagttcaaag gtttactaca
    38041 acaactgata taaagcaact taataaaatg acatatggaa atggtgtttt atcaatggga
    38101 cttgcaacag tattttatct aattggaact tgtttattta tatactatac tcaaaaccca
    38161 gatttagctc aaacagttca acaagaccaa gtatttgcat catatatagc ttatgaatta
    38221 ccagtgggta taacaggaat actacttgca gcgatatatg cagcttctca atcaacttta
    38281 tcgacagggc ttaattcagt tgctacaagt tggactttag atatacaaac tatcataaca
    38341 aaagatataa gtatggaaaa gcaaactaag atagcacaat atatatcatt aggtgtaggt
    38401 atactttcta tagctgttgc aatagtatta gcaaatggag aaataaagtc agcatatgaa
    38461 tggtttaata gttttatggg gctagtacta ggtgttttag caggaatatt tgtacttggt
    38521 gcattttgta aaaaagcgac taaaatggga gcatatgttg gattcatagt atcagcaatt
    38581 ttagttgttt atttaaaata ccgtatgcca gaagtaactt cttgggcata ttctctaata
    38641 acaatcacga cttctgtagt ggtaggtaca atagttagtg caatagaagc taaagttaaa
    38701 gcaaaagtat ctttaccaaa agctgagact actgtttatt atgaaaaata atatttaaat
    38761 gataaattgt cttatagagt gattagataa ataatttagt tactctataa gattgtataa
    38821 tatactttgt atataaaagt ataaaaatag actttataat tatataggga gatagtgctt
    38881 atgatatttg gaaatataaa tcatagtaag acatattcaa cattgcatga agatttactt
    38941 agatgttttg aatatgctaa agataattca ttaatagatt atgaaaaagg tacttataca
    39001 atagatggtg atgatatttt tgtgaatatt gtagagtata aaacttgtga aaaagaagat
    39061 agattctggg aagctcataa gaagtatata gatgttcatt tgatgcttga tggatgtgaa
    39121 cgaatagata taaattttat agaaaattta gaacaaaaaa tatatgaaga aaagggcgat
    39181 ttcttgcctc ttgatggtaa aaataatgga tacatggaac ttagaaaagg tgatttttta
    39241 gtttgttatc cggaagatgc tcatatgaca ggaataaaag ttttagaaaa agaaaatatc
    39301 aaaaaagcta tttttaaggt tttggttaga taatgataat ttatataacc actagggctg
    39361 aaaatagtga tttaactttc agcgattagt gagacttcgt aaattttagt tagattacta
    39421 ttttcagcct tagtttttta tgagaaaatt gaaaataatt aaaagcttaa aattttgtaa
    39481 aggagttaac ttatggaaaa tatagatgta ttcttattaa taggacaaag caatgctaga
    39541 ggattgggaa atccaaaaga gagcatcatt ccaaatgaaa attgttttga atatttgagt
    39601 actgatgaaa ttataaatat gagatgtgag ctagagactt cagaaggtga tggtactata
    39661 gcacctgcat tttcaaatga atggaataag cttactggaa ataaagtttg ttttattcac
    39721 aatgcaaaag atggttcaag aataaaaaac tggaatcatg ataataactg gtttctaaat
    39781 gacactatag aaaaatttaa tacaggctgt actaccttaa gtaaacatta taatatagaa
    39841 aataaatacg ttatttggat tcaaggtgaa agtgatgcaa aatatggtag tgatgtattg
    39901 tactataaag aaagtctaaa aaaaattgcg tataggctta aagaagaatg tatgattgat
    39961 aaaatgtttg taagtttaac tggttattgg cttggagaag atgaatattt tattagaaca
    40021 agacgaattg cagcagcaca ggagtcggct tgtagtgaat gtgatatatt atgtgtagga
    40081 agcaaaattg ctatgcagtt tcatgacaga ggattaacta ttgatgatgt tcattacact
    40141 caagaaggtc ttaatatgtt aggagaggac ttatgtaaaa atatttataa gtatcatata
    40201 accaaagaaa aaagtgtatt aagtgatgct atagacttat cagaagcaag gaaatatatc
    40261 tgtgaattgg aaaagataag taaaagattt gtgtaatata aaattttaaa tagagttgtt
    40321 aatttataaa aataatttgt atggagatat gttatgaaaa attacgtttg tatagatgtt
    40381 ggaggtactt caataaaata tggttttatt agagaagatg gatttataat tgataaatca
    40441 agtcttgata ctgaagcaaa ggaaaaaggt ggagaaggaa tattagccaa aataaaagat
    40501 atagtaaaaa aatatataga ggaaaatgaa ataagtggta tatgtatatc aactgcaggt
    40561 atggttgacc cagttgaagg taaaatacta tttgcattag aagaattaat tccaaactat
    40621 aagggcatgc aattaaaaaa agaagtagaa aaagagttta atataaaatg tgaagttgaa
    40681 aatgatgtta attgtgctgg acttggtgaa atgtggcttg gagcaggtag aggtgcaaca
    40741 tcttctatat gtttaacaat aggtactgga attggtggat gtattataat aaataataaa
    40801 ctgataaatg ggtttagtaa tagtgctggt gaagtaggat atatgaatgt aaatggaagt
    40861 tcttttcaag aattggcatc tactagcagt ctaattaaaa aagtagcaaa aataaaaaat
    40921 ttgaatgaaa atgacttaaa tggaaaaata atttttgatt tagcaaagaa taatgatgaa
    40981 gattgtttaa aagaactcga taatatgata aaatcattag cagttggaat cgcaaatata
    41041 tgttatgtaa taaatccaga agtggtaatt ttaggtggtg ggattatggc acaagaaaag
    41101 ttcctaaaac caaaaataga caaagcatta aaggaggttc ttatagagag agtttacaaa
    41161 aacactaata tagaatttgc aaagagacaa aatgatgcag gaatgcttgg agcattatat
    41221 aattttttaa acaaaatata aagaatagaa gggtttttaa tgagtatttt agaacaattg
    41281 gaatcaccaa cttttaaagt cacaaaatca gataaattat taatagctta tataaaagaa
    41341 aatatagatg atgtatttta taaaccaata tcacaaatag ctaaagagag caatattggt
    41401 gaagcaacta taactaggtt tgtaaaaaaa atgaatttta atggattaca ggattttaaa
    41461 gttactttag cacaagaaat atcaactatc aataaaaaaa atattataaa taaaaatata
    41521 caaaatgatg agccagcttt ggatacagca aaaaaacttt taagttcaaa tgtaaccact
    41581 ttagagaaca cagtagagat aatcaatagt aaggatgtac atgactgcgc aaggcttata
    41641 ataaatgcaa agaaagttta cttcataggt attggatatt ctggtataat agcacaggat
    41701 tcaaactata aatttatgag aataggtctt aattgtgtaa gttttgacag tagtcataca
    41761 atgataatga tgtcttccat aatggaagaa ggagatttaa taattgcaat ttcacattct
    41821 ggtgaaacag aagaaattat aaaaactgta aagcttgcaa gagccaataa tgctaaaatt
    41881 atatcaatta ctgaaaataa aaattctgaa ttaaaggata tttcagatgt acacttatct
    41941 tatgtatcgg gagaaacagt actggaaacc ggttcaatat cttctaaatt agcacaattt
    42001 ttcattattg atttagtata tacacaggta gtaaaagaac tttctaatga agctattgaa
    42061 aggaaaatta aaactacaaa tgctataaaa ttgtttaaaa atgaataaaa taagaaattt
    42121 gtaatgtttt atagagctct cttaaaaatt taggaatgga gagatattac atgtctaaat
    42181 taaaagatta taatattgat aaagtaataa tttttaataa tttaagtact aaaacgaaga
    42241 atcaacttaa agaaaaagtt aaactaaaaa gattacaaaa aaaagaaatt ttattttatg
    42301 aaaaagatag cttagacagt gtttatatac ttttagaagg aaaggtatct atttttaaga
    42361 taagtgaaaa tggagagaga aaagtaattt tcatattaaa tagtggggaa gtcataaatg
    42421 atattacact tgacgcttct aaaaactcta ctgttggctg tgaagcattt gaaaattcaa
    42481 ttgtagctta ttatagtatt gaagaatttt tagaaattat gcaaaatgat tttcaactta
    42541 caaaggatat tatttcttat atggaaagaa gaataagacg tttatataga cagttgaaaa
    42601 attctatatc cataaaagta gataaaaaac ttgcagcaaa attatatagg ttaagtagag
    42661 aatttggagt ttgctgtgga gaatggactt tactaaatgt aaatattaca gttacatatt
    42721 tagctgatat gcttggctgt aaaagggaga ctgtttccag aatgataaag gtattgcaaa
    42781 aagaagaact tattaaaatt gacaataaag gtttttatgt taaagaaact gaattatcaa
    42841 ggtattttaa aaataattaa ttatgattaa g
//
LOCUS       DAEPUT010000031        42404 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.032, whole genome shotgun sequence.
ACCESSION   DAEPUT010000031 DAEPUT010000000
VERSION     DAEPUT010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42404
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.032"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(69..473)
                     /locus_tag="KRL22_001775"
     CDS             complement(69..473)
                     /locus_tag="KRL22_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBH1272271.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
     gene            complement(665..1852)
                     /locus_tag="KRL22_001776"
     CDS             complement(665..1852)
                     /locus_tag="KRL22_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBH1272272.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCISAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGIPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            complement(1884..2207)
                     /locus_tag="KRL22_001777"
                     /pseudo
     CDS             complement(1884..2207)
                     /locus_tag="KRL22_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
     gene            complement(2236..3849)
                     /locus_tag="KRL22_001778"
     CDS             complement(2236..3849)
                     /locus_tag="KRL22_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1272273.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDEETKWIVEKIFSLAYQGYGSAKITKILREEKVPTSSWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     ATNKANKTPYSYYSCSFYGQFGKGYCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LHKIQKVGNAERIREKKKKANALKKAENRQNEIDRLFAKMYEDRACEKITERNFIMLS
                     GKYQKEQIELEQQITNLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEENERIQEIEIYYRFIGKVD"
     gene            complement(3961..4170)
                     /locus_tag="KRL22_001779"
     CDS             complement(3961..4170)
                     /locus_tag="KRL22_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HBH1272274.1"
                     /translation="MNCLERFYRKGVCVIDNTVKTIQKKNNKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            complement(4829..6043)
                     /locus_tag="KRL22_001780"
     CDS             complement(4829..6043)
                     /locus_tag="KRL22_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1272275.1"
                     /translation="MNDKNFIEELRQKREDYGVTQTRLAIACGISREYYNRIEKGKQS
                     LNDELKEIIEKQIERFNPQETLFLLIDYFRVRFPTTDALKIIRDVLQLKADYMLYEDF
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGRGCRQMESYLLAQERTWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKAKYKAGECISYFRMQKDYSGTEKCGSDTPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEVEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWKMNDDWAWFVGDNREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDKENHTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTVVPQENDGIF"
     gene            complement(6182..6460)
                     /locus_tag="KRL22_001781"
     CDS             complement(6182..6460)
                     /locus_tag="KRL22_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272276.1"
                     /translation="MKKLEFIFYGGESLIIKFLEKKLTISGKLARVLGTILMVLIGTF
                     LLYCAINPPTYFHFLKENINRIIYGVIGVLLILKALRMLFTNKLKNKS"
     gene            complement(6745..7275)
                     /locus_tag="KRL22_001782"
     CDS             complement(6745..7275)
                     /locus_tag="KRL22_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272277.1"
                     /translation="MEKILENTLLLMILPWIFVWGILCILEKRKRKNEDGNKDEKSYV
                     IQNDNIFFPFFSLGMFLFSFCLFYTVFFTEFDISEVISVSVFVIFFAILTLDSAIWRV
                     IVDGDIIKYRSFYGITRTYNFNDITKGVYTKKGSLKIYIEGKRIFTFYDNLEFSLFEN
                     QMRKRKIPLEYKRKEK"
     gene            complement(7789..7923)
                     /locus_tag="KRL22_001783"
     CDS             complement(7789..7923)
                     /locus_tag="KRL22_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272278.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGVSQTKGY
                     "
     gene            8401..9150
                     /locus_tag="KRL22_001784"
     CDS             8401..9150
                     /locus_tag="KRL22_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH1272279.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELIST
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(9316..9681)
                     /locus_tag="KRL22_001785"
     CDS             complement(9316..9681)
                     /locus_tag="KRL22_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1272280.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(9697..10473)
                     /locus_tag="KRL22_001786"
     CDS             complement(9697..10473)
                     /locus_tag="KRL22_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1272281.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            complement(10884..12311)
                     /gene="ascB"
                     /locus_tag="KRL22_001787"
     CDS             complement(10884..12311)
                     /gene="ascB"
                     /locus_tag="KRL22_001787"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH1272282.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYIREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            complement(12372..14300)
                     /locus_tag="KRL22_001788"
     CDS             complement(12372..14300)
                     /locus_tag="KRL22_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1272283.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIV
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            complement(14445..15288)
                     /locus_tag="KRL22_001789"
                     /pseudo
     CDS             complement(14445..15288)
                     /locus_tag="KRL22_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            complement(15603..17003)
                     /locus_tag="KRL22_001790"
     CDS             complement(15603..17003)
                     /locus_tag="KRL22_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1272284.1"
                     /translation="MKNKYEDVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGIPIQGVIYAASV
                     IPALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYIFG
                     VEKNVKEGIDNVVEEV"
     gene            complement(17042..17713)
                     /gene="pgmB"
                     /locus_tag="KRL22_001791"
     CDS             complement(17042..17713)
                     /gene="pgmB"
                     /locus_tag="KRL22_001791"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH1272285.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLERGKPYPDIFIEGSKMLNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLA"
     gene            complement(17715..20105)
                     /locus_tag="KRL22_001792"
     CDS             complement(17715..20105)
                     /locus_tag="KRL22_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH1272286.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDYFD
                     LSKGITSEHTRILDLNEGILKRSFIWENSCGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKIDVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSTLDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            complement(20131..21579)
                     /locus_tag="KRL22_001793"
     CDS             complement(20131..21579)
                     /locus_tag="KRL22_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH1272287.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MSYYLKSNKIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            complement(21984..22871)
                     /locus_tag="KRL22_001794"
     CDS             complement(21984..22871)
                     /locus_tag="KRL22_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1272288.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            complement(22971..23420)
                     /locus_tag="KRL22_001795"
     CDS             complement(22971..23420)
                     /locus_tag="KRL22_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1272289.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASVVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYEV"
     gene            complement(23410..25317)
                     /locus_tag="KRL22_001796"
     CDS             complement(23410..25317)
                     /locus_tag="KRL22_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1272290.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDELMYIYIFLVSSGFSSESNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(25585..27480)
                     /locus_tag="KRL22_001797"
     CDS             complement(25585..27480)
                     /locus_tag="KRL22_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1272291.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(27516..28394)
                     /locus_tag="KRL22_001798"
     CDS             complement(27516..28394)
                     /locus_tag="KRL22_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBH1272292.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKSAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(29099..30532)
                     /locus_tag="KRL22_001799"
     CDS             complement(29099..30532)
                     /locus_tag="KRL22_001799"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH1272293.1"
                     /translation="MKSNQEFLWGGAVAAHQVEGGYNKGGKGISIADVMTAGTHTISR
                     KITDGVIEGLNYPNHEAINFYENYKEDIRLFAEMGYKCFRTSIAWTRIFPKGDESTPN
                     EDGLKFYDDLFDELLKYNIEPVITLSHFEMPYHLVKNYGGWRNRKLIDFFVNFCEVVM
                     NRYKDKVKYWMTFNEINNQSITTNPIYAFTNSGIIYEEQEDKEEVMYQAVHYEFVASA
                     KVVKIGHEINPEFKIGCMVAAMPSYPYSCNPEDMIKFVESNREQLMFTDVHVRGHYPR
                     HTLKLWERKNYNLDITEEDKKILKEGIVDFIGCSYYLTTVVTADKTMKTTGNDSAGKA
                     DVVENPYLKISDWGWNIDPVGLRFYLNQLYDKYELPIFIVENGFGAEDVLKSDNTVDD
                     DYRIEYLASHIREMKNAIEIDGVDVIGYTVWGCIDPVSFTTGEMKKRYGFIYVDKNND
                     GSGTLKRYKKKSFDWYKNVIKFNGEIL"
     gene            complement(30555..32396)
                     /locus_tag="KRL22_001800"
     CDS             complement(30555..32396)
                     /locus_tag="KRL22_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1272294.1"
                     /translation="MKFERESEEIIKYVGGKENIISLVHCATRLRFKLKDTSKTNKEE
                     LLKMKDVLSVVNSGGQYQVVIGNKVTDYFETIIKKAVLQGQNTEEQGEKVSIVSKIFE
                     SISGAFSPLIPALAGAGMIKALLTILTTMKWMSDTSSTYAILSAAGNAVFYFLPIFLG
                     ITLAIKLSANPYVGGVIGAALLDPNFTALIGAKGGANFFGMPVTAIDYSFGVFPIFVA
                     IFIYYYVDKLLKKIILKDLQLFLVPMISLLVMVPLTVILFGPIATNVGDIISNIFMGL
                     FEFNRVIAGAAIGIAMPFLAVLGLHWGFTPITLQNLATMGGDPIEGAAVAAVFAQIGI
                     AIGLFMKVRKSKKNSELKVLAGSTAVTGILAGVTEPIIYGIILRYRRMIPVLAIAGGI
                     GGGICGVFGVTCNAYVFHNIFSMPVYTPFLGYILGIGTALVLGAVLSYFFGLSKEECE
                     EGNEEVAFDEDDGIEEILSPIEGLQIELSEVEDEVFASGTIGNGMAIIPSKGEVVSPV
                     NGTITTIFPTKHAIGITSDKGVEILIHVGLNTTMLDGKYYTTHMNAGDKVKKGDRIVS
                     FDKDKIEGEGYSIVTPIILTNTNDLADVIVKENKHIKIGTPVIKVVY"
     gene            complement(32522..33355)
                     /locus_tag="KRL22_001801"
     CDS             complement(32522..33355)
                     /locus_tag="KRL22_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1272295.1"
                     /translation="MVIKKVFNNNVVFARDNSGQEVILMGKGIGFNKFTKDLVEIDKI
                     EKKFIFNNEESLSELHSLLDRIPLKDVELVSEIIQMGREELGDNLNDSILITLSEHIS
                     YMLKRMDEGLVFQSPLQWEIRQIYPNEYNFSKKAVEYLRKKLDKNIPDSEIAFITIHF
                     ANAQLETKDMQETLLLTKIIDNVLDIIKYHYGIEINEYSFDYTRFISHLRCFIKRQLS
                     GENTNVDTSLLDIIKMKYKSDYNCAKKVKNFLEKTYKWKISENELLYLTLHLNRLSNI
                     K"
     gene            complement(34399..34611)
                     /locus_tag="KRL22_001802"
     CDS             complement(34399..34611)
                     /locus_tag="KRL22_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272296.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            complement(34612..35028)
                     /locus_tag="KRL22_001803"
     CDS             complement(34612..35028)
                     /locus_tag="KRL22_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272297.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(35098..35511)
                     /locus_tag="KRL22_001804"
     CDS             complement(35098..35511)
                     /locus_tag="KRL22_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272298.1"
                     /translation="MSKSELGVKANLVSELMMLSYFFIDLLLQKFIFKGEGIWFTFII
                     LLAFWVCNLMYNKKYNDLVDEASKLMLLKVDQIASKIMLYSMFVIAVLFSVNHTRALD
                     ISNLDIGIMLLAVLFIQSLSKLILYIYFDKKGICN"
     gene            complement(36345..36974)
                     /locus_tag="KRL22_001805"
     CDS             complement(36345..36974)
                     /locus_tag="KRL22_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBH1272299.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDVRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(37053..38015)
                     /locus_tag="KRL22_001806"
     CDS             complement(37053..38015)
                     /locus_tag="KRL22_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH1272300.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQNQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(38777..42175)
                     /gene="cbpA"
                     /locus_tag="KRL22_001807"
     CDS             complement(38777..42175)
                     /gene="cbpA"
                     /locus_tag="KRL22_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HBH1272301.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAEGDTNAGNAGGDANAGNAEEDSNAGNAEGDANAGNAEEDANAGNAEED
                     SNAGNAEEDMNALVVEEATAEDPTSVGDFKISGGEINVDFKFASGVLTILSGKQMTIQ
                     NNNPNTPTTHRIVIPKDVKAELIFDGVNIKTASNSPFTLTPDKDGGAYAHVILQDGSE
                     NKLESGDVYYPGMRAGKGTTLIIDDSVVNRDIEGEFIVPEGGKIPRDVTLENGDKLKK
                     GDRLTLLDSNNRGSLKVVGNYYSAGIGGGNTESGGNIIINGGAITAIGQESSRNTGYG
                     AGIGGGGNGSGGDITINGGTITAKGAYHGAGIGGGYYTTTKNALSPSVVDPSTGSGYS
                     GNITINGGLSYSYGGAHGSAFGDGCVNPGTNRGYRILVTGGTILPYMTGVGDWIFDLS
                     ATTGDVIVTGGSLKATTFKSLGGAVAYGDLEKKTKVFMNKISLKYLGQDKVSTTLVDD
                     FKMLIDGKIYPYGAPSYTDDQGVLYLWFSDQFKGSEVSVNLVVIDKITGGNIKPDDFY
                     VKDIGSGSQFLKQYEEFTIDDTPPYLIIKRYDGLPFEEDVEKLFLDWILKDGGIPIIT
                     PKGEKLTDKKFMTISSQRLNEETMEPDTNLGSDDLTKQVDAGKYQLSITSTQFSNVYP
                     FNEAYWGHRAYYKAEIIPADTETSLVVEESKAKTDVFKPTDTFTLNVTISPDKKEGPD
                     CASPRGYVQFYINGKEYKDPVELKTHNKGSESHNYSTASIEWRPLDSNHHIFTTEQTI
                     TVKYIGDDINYIEGSEDEKKLKLDMTNVDVDGDGIPDINIDTDGDGRPDINIDTSGDW
                     KPDINIDTDNTGEWKPSTEGGNGDGIWKPDKNIDTNGDGNPDTDYNRPAIDTDNDGVD
                     DYWKPDKNVDTGSGGYDTGNPNLNKPDPDNGGNSKPDPDNGGNSKPDSGNGGNSKPDS
                     GNGGNSKPDSGNGGNSKPDPDNGGNSKPDPDNGGNSKPDIDTDGDGKPNINIDTDGDG
                     KPDINIDTDGDGKPDINIDIDGDGKPDINIDIDGDGKPDINIDTDGDGKPDINIDTDE
                     SLDSNVGQNVQTGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
BASE COUNT        13429 a         7742 c         4608 g        16625 t
ORIGIN      
        1 ttttatttaa acgctctagt gatattttta aataaatttt aataaaaatc attctatttt
       61 gtcataaatc atttatctgg cttatattta agatatattg gtggatactt tacacttttt
      121 aattcctcat tacttcttaa aagtttatta ttattttcca tatcataaat ttgtaacatt
      181 actttattta catatagagc ataataatta tcactataaa aatattgata ctcatatcga
      241 gggtcatctt tgtaatacac tttgtatagt attccttcgt aacttgcctt cttggctttt
      301 tcttttgtaa tactttttat attatctttt gaaatatctt gttttaccat atacttatca
      361 atatatgttt cagcatcttt ccatggttta atgcagtttt tatatacaac aaaccctgtt
      421 acacttataa tacctataat taatactata aaaataactt tatatttttt catattaatc
      481 ctccttcatt tattatttaa aactcgatat aatgcactaa aaaaaggatg ttatcttttt
      541 tattaaaata taacatccct catatttagc atcaatatat atgccccaac tggtaggtta
      601 aaagacccca ctgtcagtac tttgattaaa ttacatgtat gtatatatat ttttaacaaa
      661 tctattatat gtcaacttgt ctactattac atataatctg taatattaca tctgctgctt
      721 tttttgagcc tcctgcatta taaaagcttt ttgatagttt agttgcattt tctttatatt
      781 cattgtcatt tataacttga aatactgctt ttttaatact ttctgactta tcctctttta
      841 acataattcc tgctcccaaa tgaacaactc tcttagctac cattctctgc tccgaatgtt
      901 gaggaaataa taccataggt attccataat ataaactttc attaacacta ttcatcccag
      961 aatgagtaac aaacacatca gttttttgaa gtatagcaat ctgttcaaca ctatttttga
     1021 cctcaaaatt atttggtata tttcctaaac ttttaatatc agtacttcta ccaacagaca
     1081 taatcacatc aacatcagaa tctttaaatg cacttataca gtttttataa aagctaacat
     1141 ttttattatt aattgtacca agcgaaatat atattagctt tctttttctc tctttaggtt
     1201 caataatcaa ctttgatact gatggaccta caaatgaata cttactagag aaggtttcta
     1261 ccattggttg aaattctttt gatgtatata caatggtatc cgtatcatta tcattagaaa
     1321 ctatagaaat aaaatttttt acttcatacc cttttctttg taaaagcttt atttttttat
     1381 taatgcgtct tacaccaaaa atcatacgta taatttctat aaagttttgt ttcatcaact
     1441 ttgctgtatg tttattaaat gcaaaagttg ttgtagagca tacatatgga atattaagtt
     1501 tttgtgcaaa taactttccc caaaaactta atgaatctga tacaatgcaa tctggattaa
     1561 aatctttaag ttctctacaa actttttcat ctaaagaaat agtagtatct actatcatct
     1621 caattaatcc aggaaaatcc ttaccaattt ttttctcatc tccagggagt aattctggaa
     1681 ggtatttatc acaacaaata aattttgctc cagcaccttc aattttatct ttaaattcat
     1741 taaaagaata atacaatacc tcatttcctc tatccactaa ttcacgaact acttcaatag
     1801 taggattagt atgaccatat gcaggaatgc taaaaaatac tattttactc atatttcata
     1861 cctcctttta taattttttt aaatcattct tctttatgta ctactcccac atgacctata
     1921 aaatttatca aatcacgttg atgaacaatt cctaatcctc tttcctcatc tccaagtacc
     1981 aataatttat ctcctgcatt tatattaaat acttctcttg cttcttttgg aatgacaatc
     2041 tgaccacgtt caccaactac aactgctcca aagaaaaact ttcctttagg aggtactata
     2101 atacctgttt tttcttccga atgattaact aagtcatcta gtttaacatt gtacaatttt
     2161 gcaagtttaa tgcaactacc tatatcagga atagattctc cgctttccct tagttaaaga
     2221 tatgacccct atttatcagt ctacttttcc aataaatcgg tagtatatct ctatttcctg
     2281 tattctttcg ttctcctcat tcgttgttgc ttcgtgaatg agtatttttt ctatcattgc
     2341 atttaataac ggtgctgtca gttcctttgg tacggaatac tccttgatta actcaatcca
     2401 cttttcagca cctatcatat cctgttccat tttacttaat tcttctctta ggttggttat
     2461 ctgctgttcc agttctatct gctccttttg atatttcccc gacagcataa tgaagtttcg
     2521 ttctgttatc ttctcacagg ctctatcttc atacattttc gcaaacaaac ggtcaatctc
     2581 attttgtcgg ttctccgctt tcttcaaggc atttgccttt ttcttctttt cccgtattcg
     2641 ctctgcattg ccgactttct gtatcttatg caataccttt tcttcgtcct gctgtactgc
     2701 cttagcccaa tactgcaatc gctccaatac agcttgatac agcacatcat agcggatata
     2761 gtgcatagaa caataacctt taccaaactg tccgtagaaa ctgcaagaat aataactgta
     2821 tggtgtctta tttgctttat ttgtcgcaaa tctcatagac cagccacaat ccgcacattt
     2881 gacaagccct gcaaatatcg gcgttgcctt ttcctttgtc tgtctacgcc ttgattttat
     2941 ctgttcctgc acacgataga acacttcctt gtcaataatc ggttcgtgcg tgttttctac
     3001 tcgaaaccat tcactttcgg gcttacgaac tttcttcttg ctcttgaacg ataccgtaga
     3061 ctgcatattg tgaacgctgt tcccgatata gacttcactt tttaagattg ccttgacatg
     3121 agcaatcgtc cactcataac gcttgctttc aggtttgccc tcaaaaatat gtgcaaaagt
     3181 gccatacctt gtaaaattca gccaagacga tgtcgggact ttttcttctc gcagtatctt
     3241 tgtgattttt gcactaccgt aaccttgata ggctagggag aagatttttt caacaatcca
     3301 ttttgtttcc tcatcaacca gcagtttccc tttgatgtcg gggtgtttct tatatcctaa
     3361 cggagcataa gccccataat gagcaccctc tgcaaatttt gtcttaaacg ctgatttcac
     3421 tttacggctt gtatctcttg ctacccattc attgatgatg ttcttaaatg gtgcaatctc
     3481 actttcgcct ttttcgctgt ctacaccgtc gtcaatcgct atgtaacgga cattatggct
     3541 gggaaaatac aattctgtat attgtcctgt cataatatag ttcctgccaa gtcgggaaag
     3601 gtctttcgtt acaacacagt tgatttttcc tgcctctata tcctcaatca ttctctgaaa
     3661 actcggtctg tcaaaatttg ttcccgacca gccgtcatca atatattcat caatcacatt
     3721 caaatgatgt tcttttgcat atagacgcaa catacttctt tgtgtggtaa tgctagaact
     3781 ttcgccttgt aattcatcat ctcggcttaa cctaagataa agtgcagtat tgtaaatctg
     3841 ttgtttcatt gtcagttatc ctcctttata actaacccgt gtttacaata cctgcttgca
     3901 agtaaagtat aacacgggta ctttttgcca ttcaatctat ttcttacaac tgcaccgaat
     3961 ttatgcgatt gtctgctttg ctttttccag cataacatca gtcagaagtt cttccattgt
     4021 ctttcctttt tcggaaaaat gctcttttac aacaatcttt gtctttcctc tgtttccaat
     4081 gccacacttg ttatttttct tttgaattgt ttttacagta ttatcaataa cacatacccc
     4141 ctttctgtaa aatctttcta agcaattcaa cggcttttgt catagcccac aggacttcca
     4201 cctctgcatt atccaatgta gccgtaccca ttgcgtgcga cgctcttaac gctcaagctg
     4261 tggctgtacg ggagtatcat tatcagacag aacaggtcat agcgataaaa gaggacaagt
     4321 cttttacaag aacacaaata gattttcgct cgcttttgca ggggaaaggt catggcgtat
     4381 ctgtttcaac ggctcgctgt ctgtctaagg tattgaattg ctttattcag ttgtcaaaga
     4441 acacgaaaga agaaaatcgt ctttcctata tatcgcgttg gaaaagagca aaagcgtaac
     4501 caatattcaa aacttttttc ttttcctgta tcatataggg aaagaaagtg tcattctgct
     4561 aagttactga tgaaaaaatt tcttttctca ccctaactac ccatgcaaca ccgttattgc
     4621 caactatgga atgaaagatt ttctttgctc catataggga acggcaactg ccaaatgtta
     4681 agttgagaat gaaaatattt tcttctttca ctccatatag ggaatggaaa cctcaattta
     4741 atgagtggtt ttgaaaaaag ttagatttcc ttttctcgca gcatatctgt acgctagtta
     4801 atgctttgtt gcagattttt caaagaaatt aaaaaatacc gtcattctct tgtggaacaa
     4861 cggtatctat gcgttcttct atggttgatt tttctaactg taataaatgt ttatgcttgt
     4921 ctttgagctc tgcctgctca atcatatctt tcagtatcgt tgtatgattt tctttatcca
     4981 atgcctgtac catttttatc gttggtgcaa cttgtctttg taaccaatgc aatgcctttt
     5041 gtaaggtata aggctctggc tttgtggtta agcgtatagg ttctctgtta tcccctacaa
     5101 accatgccca atcatcattc attttccatt gacttttagg tttatcgtcc tctctatcta
     5161 caaagcgaac ataatgattg atgatagaaa aagcggtgcg ttcagcgtcc cgataggtca
     5221 gtaaatctac aactgcataa taggctcgtt cattcttcat gcgtatttca aaacggttct
     5281 tgatttctgt atcttcaact tctgtgccat tcttgacata ctgctcataa ttcttctgat
     5341 aagcacacat atataattcg ctacttgttg aaccaagata taaggtttct cctgtgttct
     5401 ttggtgtatc actcccacat ttctctgtac cactgtaatc tttctgcata cgaaagtagg
     5461 aaatacattc tcctgcttta tattttgcct ttaattttgg aatatccaat attcctgctt
     5521 tatcattgat tgccaagtca agccgtttca tcacaccgcc tgccgtcata caatcaagca
     5581 taaagtcata ccatgtgcgt tcctgtgcca atagataact ttccatttgc cgacaccctc
     5641 tgcctttcag ttctaacaaa acgcctaaat gctcttgcat agaacacatg atattgatgt
     5701 ctcctaaaac atatttgctt tcatatccgt actttccaaa atcttcataa agcatataat
     5761 cagctttcag ttgtaataca tcacgaataa tctttaatgc gtccgtagta ggaaagcgga
     5821 cacgaaagta atcaatcaat aagaataatg tttcttgtgg attgaaacgc tcaatctgtt
     5881 tttctattat ttcttttaac tcgtcattca atgattgttt tcctttttca atgcggttgt
     5941 aatactcacg gctgatacca caggcaatgg caagccttgt ttgtgttact ccgtaatctt
     6001 cacgtttttg tcttaattct tcaataaagt ttttatcatt cattcttcaa ttcctccaat
     6061 taaaaaaagg caactaccgt atcttgataa ttgcctgtca ataaaaatct gtatagaaaa
     6121 agcagtcaat cctaagacta actgcttgtg tgtatgaata tgaaatttta aagctgaaat
     6181 tttatgattt attttttaat ttattcgtaa aaagcattct tagtgcctta aggattaaaa
     6241 gaactccgat tactccgtat ataattcgat ttatattctc tttgagaaag tgaaaatatg
     6301 ttggcggatt tattgcacaa tatagtaaaa aagtaccaat taacaccatc aggatagttc
     6361 ctaaaactct tgctaatttc cctgatattg tgagtttctt ttccaaaaat tttattatca
     6421 aactttcacc tccataaaat atgaattcta attttttcat agtgataatg gcataattta
     6481 tatcacatca tattaaaagc gacttttcct tgtatatata gcgtttttcg cttgtaaatg
     6541 tctcttgtct cttgcttttt gtgcccccct tgttagataa cgagggctta atcttcgctc
     6601 gccacaggct cgctcacaga cgaagtgaac cagccacttg caagacatgg cagaaaaatc
     6661 tgaaagattt ccctgccacc gtgtctggat cactccgtct ttaaagtggt aatattatta
     6721 aactaattct gaacaatttc cttattattt ttctttgcgt ttatattcta aaggaatttt
     6781 tctttttctc atttgatttt caaataaaga aaattctaaa ttatcataaa atgtaaaaat
     6841 tcttttcccc tcaatatata tttttaaaga acctttctta gtataaactc ctttggtaat
     6901 atcattaaaa ttatatgtcc tagtaatccc ataaaatgaa cggtatttga ttatatcacc
     6961 atctacaatt actctccaga ttgcactatc taatgttaaa atagcaaaaa atatgacaaa
     7021 gacagaaact gatattactt ccgatatatc aaattcagta aaaaacaccg tataaaaaag
     7081 gcaaaatgaa aataaaaaca tacctaacga aaaaaaggga aagaatatat tatcattttg
     7141 tataacatag cttttttcat ctttatttcc gtcttcattt ttccgttttc tcttttctaa
     7201 gatacatagt attccccaga caaatatcca tggcagtatc atgagtaata atgtgttttc
     7261 taatatcttt tccatatatc tctccacgtt ttccaaaatt gataaatata ttatagcact
     7321 tacctcattt cagttcatta cttttctgct atctgtcaga atatttttta tcccatgcct
     7381 tatcaagagt gcaagcattg cttacgcaac aagctcttga caattcatgc tctaaaaaat
     7441 gatagataat caagcagaaa aaagaacaaa ttatgctgtg ttacagcaac aaaaagacat
     7501 ctcatatctt gtatgaaata ccttttttct tttttatgcg atttttcttt atcgtatcaa
     7561 ggttctttca atcgtggtaa atttcttttg tattttcatt cctattactt aaagtacttg
     7621 tgtttatgca gataatcaga tttttaatct tttttctaaa taaaaaacga cctgtcatta
     7681 cttttagact atcaagtaaa atttataaca cataggaaaa acactatatt tcaagtactg
     7741 ttctcttata ttcagtattt ttgcaagcag gtaaacacag gttattcctt aatatccttt
     7801 tgtttgggaa actccacttt cccattttgc tattgattgt ctagaaacat taagtttttc
     7861 agctaattct tcttgtgtat actgattgat ttttcttaga ctttttaaat tctcattaat
     7921 catatttttc atacctccta tgtttataat attggattta ttatttaaat tctatcaact
     7981 aatcttaaca ttcatatata tatttatata cttttattat ataaatttat tgttcaggta
     8041 acatatttcc ttaagttatc gtaaacaaaa aaacaaacac aaatctacta actgttgtta
     8101 aagtatttaa gttaaggtca tttacattat caaatatttc tacaccttca aaataacctt
     8161 tatatttata atctttcata agcaaattat tatcccttct catatacaag tccagttgat
     8221 gtcttgttgc taaatttaat ggtaatcaaa ttctttacca ataagtataa aaattactaa
     8281 tgtgttataa ttttcttaac tactaaattt tacatacatt tgaatagaat atatcaataa
     8341 attactataa taaataaaaa attaagagtt aaaataaaaa atagttaggg agatattatt
     8401 atgattttat attttagcgg aactggtaat agccgatatg tggctcgtaa aattgcacaa
     8461 gaattaaatg atgaactgat atcactaaat caacttataa aagaggaaaa aacagatgaa
     8521 ttaatatcaa cagataaacc attcatattt gtatgtccta cttatgcatg gagattgcca
     8581 atagtggtta cggattttat aaaagaaaca aaatttctag gaagcaacag agtttacttt
     8641 gtaatgactt gtggtggaga tacagcaaaa tccataaact atattcaaaa actatgtaaa
     8701 tacaaggaat ggcaattaaa aggtatggca gaaattaaaa tgccagagaa ttatatagct
     8761 ttattttcta caacagacaa agaaacatca aaacaaatga ttaaagaagc agataaacaa
     8821 atatatagga ttatttctga tatacgcaat gaaaatgaat ttgaaactat tactcctagt
     8881 ggcttaggag gtacaattaa aagtggtata ataaatacag ttttttataa gacaattatt
     8941 agtgccaaag gatttcatta tactgataaa tgcattggct gtggaaaatg tgtagagcta
     9001 tgtcctttaa ataatattaa tttaaaaaac aaaaaaccag tttggaaaaa taactgtact
     9061 cattgtatgg catgtatttg tggttgcccc actgaagcta ttgagtataa aaataaaact
     9121 caaaacagag aaagatacta tttagaataa tatattctta atatttaaac cattataaaa
     9181 tgaactatac ccattgtttt atacagtttt acatatttta accgtctcct aaaatgggta
     9241 tagttcaaaa gatagtgtct caaagtgaat tttttagttc ctaaatcaat ctttttgtat
     9301 taaatcaagt ataatttaat caccttttct tatatcattt tcactaatat gttgtattcc
     9361 aacaaatata agatttatta gctctgttag tgacttccat tgtgattttt ttgaatcaag
     9421 ataataataa tttttcgttc cttctctacg taaattaaca atctctgctt cttttaatat
     9481 cttaagatga tgagatacag caggacgaga aagatgtgtt ttttttgtga tttctcccac
     9541 tcgtatacca ttaaaatcac tctctaagag agcaattaaa atcaattgtc tagtctcatc
     9601 acccatagca gagatagctt tgcgacattc tttaaattta gacgttattt cttgcattct
     9661 ttgttgacat tctttttcca taaaatccac cctctcttat aagtatctaa cagttgctac
     9721 ttctttctgt gcagtacgtc tatatttaac atctgggtat ccaattacta atgttgtaag
     9781 aacatgatta ctgcgtttta gacctaaaag cttttttaat tttggcgaat tatttgctac
     9841 atctgaaaaa tatccactaa ataaaacacc taggccataa gactctgcca ttaatgccat
     9901 atttgatgct gcaagtgaac cactaatctt atcttttgta attatcatta ttgcaatagg
     9961 agcatgctta aagaaaaagt tatcgtcaat ctcaacttct tttgaatatt taatagctat
    10021 atttgcaata ggttttattt ttctaaaaaa tttcactgct tcgttttcat aaattgactt
    10081 tttattgtct aaaacaatat atgatacatc ttgtgaattt ttagcactag gggtatacct
    10141 acctgcctca ataatttgct ttataatttc tgaagaaact tctttgtctt taaatttacg
    10201 tatacttctt ctagatttaa ttgccattag taattcatct gaatctagct ttggcttatt
    10261 tgtaagttct ataggaggtt catcaaatcc tgtcaaggta atagcttttg tgggacatat
    10321 tgctgcacaa tgtccacaca ttagacaatc ttgtttttta attactgact ttttattttc
    10381 tataattata ttgtttactg gacaatcatt tttacaaagc ccacatccaa tgcaaagttc
    10441 tttgtcaact tctattatat gttggtattt catattcatt catctacctt tcgtttatta
    10501 gtttaaacta ttataacacg tagacatttt ttatattcat tggtaaagaa tttgattacc
    10561 attaaatttt taatttctct attaaataaa tttttcatag aattttaaag tatcatagtt
    10621 tatacataat aaaaaagaca agcttaaaac ctaagcttgc ctttttcatc ttttattaca
    10681 aagtaaattg cacttacttc ccatacttct taacaatttt attttctaaa attttatttg
    10741 tgaatcatac tattgcataa atacaatgta aaataattct gtattgattt tctatagtta
    10801 aaaaagataa aaattatact tattattaat ttttatactc ttcttattta atacaaattt
    10861 cttatttaac atagatttct tgtctaatat aaatcttcac catttgaagc aattactttc
    10921 ttataccatt caaaactttt ctttttcatt cttcttagac ttccattacc actattgtct
    10981 ctatctacat atataaatcc ataacgcttt tccatttcac ctgtaccagc acttactaaa
    11041 tcaataggtg cccatgtagt ataacctaat aaatcgaccc catctataga aactgcatca
    11101 tgcatagctt ttatatgttc tcttatataa tcaattctgt aatcatcttc tacataacca
    11161 ttttcatcag ctatatcttt agcacctaat ccattttcta caataaatag tggcttttca
    11221 tatctatcat atacatgatt tagtgtaatt ctcaaaccta atgggtcaat tggccatccc
    11281 cattgactgt atgaaagata tggattttta gcagatgtaa atatgtttcc ttcagccata
    11341 tcatctgcat tttcatcggt tctaacacaa cggctattgt aatatgaaaa tgaaataaaa
    11401 tctactgtat atttattcaa taattcaata tcaccaggtt ccatttctgg tgtaatacct
    11461 ttttgctcca tatactttaa cgcatagtta ggatatttac ctttagattg tacatccaca
    11521 aagaagtaat tttctctatc taactttgta gcttcccata catcattagg attacaacta
    11581 taaggatata cacttccagc tgcaaacata catccaatta agttatttga atcaacttca
    11641 tgtgctattt tagttgcaat tgcactagct acaagctcat gatgggcagc ttgatatttt
    11701 atcttttcaa catcttcacc ttcttcaaag caaataccag cacccataaa tggagcatgt
    11761 aaaatcatat ttatttcatt gaaagttagc cagtacttca ctaatccttt atatcttcta
    11821 aagataacat tgcataattt ctcatagaaa cctatcattt ttcgattacg ccatgcacca
    11881 tactttttaa ctaaatgcat tggacaatca aagtgtgtaa tagtgactaa aggctctatt
    11941 ttatattttt tacactcctt aaatatattt tcataaaatt gaagtccctt ttcatttggt
    12001 gtttcttcat caccttttgg aaatattcga ctccatgcaa tgctcattct atatacttta
    12061 aatcccattt cagcaaataa ctttatatct tctttataat tatgatacat atcaatacca
    12121 gttttagctg gataataatg ctcatcatca aaatcaaaca tttttagttt ccctgtaata
    12181 actgctgttc tatcttttcc tgttggacat acatctacat ttgccaatcc tctttcgtct
    12241 tcattgtatc caccttcaca ttgattggcc gcagtagctc ctccccataa aaaatcattc
    12301 ttaaaactca tagtcaaagc ctcctaaaat tataaccaaa gcactagatt atgctaatac
    12361 ctcaatcttt actaaaataa gactgtaatt agattgtctt ctaattcaat atttttactt
    12421 tctgtttcta ctacatctaa aaattgtgat gaatttgtaa taacaattgg agttacagta
    12481 ctatacccca actcttttat tgcatcaaca tcaaagttta atatagtttg accttttgta
    12541 attctatcac cttgttttat acatgcctca aaacctcttc cctctaattg aatagtattt
    12601 aatccaatat gaataagcac ttcaacacct gtatcagaaa gaatccctat agcatgtaga
    12661 ctaggaaata aggttgtaac taccccatct actggagcaa ctacttttcc atcactaggt
    12721 attattgcca ccccttgacc tagtacacca gatgcaaatg ctgcatcctc tatatcactt
    12781 aattttaata cttcaccttt tataggactt gttactattt ctctttctaa tttagtagac
    12841 ttgacttctt ttatttcttc tttaccctta tttcttactt ttttagactc ttctactttc
    12901 tcatctttat ataaaatcat agttaataca aaagctacga ccattgatat aactatacca
    12961 gaaagagcta ctattaagtt acccattccc ccatctggtt caatcattgc tggaagttca
    13021 aatattccca ttcctccagt tataaatttt ctaagattaa agaatccata gaaagcgcct
    13081 ccaataccac tagcaataca acttattata aatggtttct ttaaaggcaa taatattcca
    13141 taaattgctg gctctgtaac tccaaatata ccagatataa agtttggtat tgccatctct
    13201 tttagttttt tatctttagt cttgaaaaat attgccaaca caactgccga acttgcaaat
    13261 gtacaggcaa agaatggcat cataacatta tcatatccta aagtcataac attgtttata
    13321 tatacaggaa taaatcccca gtgcatacca aaaataacaa gaatttgcca agtaaatcct
    13381 actatagcac ctgccaatag tggactaaaa tctcttattg aaattacaat ttgtgaaata
    13441 agtgtagaac caaatgttgc tatagggcct ataactataa gtgcaacagg cactgttatt
    13501 aataatgtaa gcattggcac aaagaaaaac ttaactaaat ttggaacaca cttattaaat
    13561 aatttttcac acctagaagc aaaatacact ataaatataa ttggtacgac tgttccagta
    13621 taatcaattg atacaattgg tagtccaaag aaatcaatat atactggtga tgcaaacatt
    13681 gttcctttaa ataaagtgta catcacatct gctcctgctg atatactgct accttgtata
    13741 gcaggataac atactgcagc tcctagtgct aatcccaaca ttggttttaa tccaaacttc
    13801 ttagctgaag tatatcctaa gaacaaagga aggaatgtaa ataatgcatc tcctgctgca
    13861 tttattacca tataaccacc agatacatca ctatataatc ccattgctac aaataatgca
    13921 ttaaatcctt tcaacatacc acaagctgcc attattccta acactggctg aaaaattcct
    13981 gatattatat ctataccttt atctagtata ttacctgatt ttttagtttc tgaacttgta
    14041 cttgaatcat ctaaaccaat tatttcaact acatctttat agacagcttc aacatgattt
    14101 cctataacta cttgatattg tcctccactt ttcattacag taacaatacc ttccatgttt
    14161 tttaatacat tgtcatttgc tatactttca tcttttaaag taaaacgtaa tcttgtaata
    14221 cagtgtacta acccactaat attttctttt ccaccaacat tgtttactat ctcttgtgct
    14281 aattgtttgt attttcccat ttttctcctc catatttcgt ttaaattaat tttttgaaat
    14341 ttgaaggttt ggccaactca atgttaccat ccaaccataa gtataatttt gttagtatca
    14401 ctcctttcaa tcattcttaa tatactactg aaaaattatt tcacttacat atttgagtct
    14461 ttaactactt tagctaaatg tattgttaaa tatataagct catcatctgt taatatgtag
    14521 ttatattgtt ttttaatgaa atttttaatt ttaactacac attcaaactc tttattatat
    14581 ttagatttaa taatgcttag taattctttg tctgtctcac cttcatgtgc actatctaaa
    14641 agcaatcttt gcgcaaaaaa ctttaaatgc attataaatc tataataaaa cactgattct
    14701 tcatgaaatt ctatcctaaa atgataccta actatgctaa gtacttcttg tattaacttc
    14761 gtaatatcag atgccaaagt atgaccttca cttaactgag cattcactat atgaaaggct
    14821 ataaatccag cctcatcttc tggtaatttt atacctgttt tgttttcaat aatatctagt
    14881 gctttcattc caatttcaaa ctcttcttta taaaatcttt taatttccca aaggattgca
    14941 ttttttacat ttattccttc tttcatcctt tgaattgcag aatatgtatg gtctacttaa
    15001 ggatatgtaa atactttcat ttagcttctt gtttaacttt atttgtgcgt attctataat
    15061 ttcacttgat aatttcatgt gttctatagg aatattattg agtaattctt gtagtttgtt
    15121 tgatatttct ttatttgata ttctaaatac tttatttact ttagttttat ctattagatt
    15181 gccttttgat ttttgataac caattccttt acccataacg ataacttctt catcattatc
    15241 atctaatgtg attacaacat tattgtttaa tatcttatta attatcatga ttatcctcct
    15301 tttaagcata aaaaaagctt atccataata atgggcatac tccttcctag gatactgcta
    15361 ttattaatga ataagcttag cttgtactta aacaattact acctaattcc aattaatatg
    15421 ataaaacatc agacatattt tgtcaacttt ttatttccat acttcatcaa tcttttatgt
    15481 tgctttttgt cagttctaat aattattctt attaatatta acttatttct ttgcatcaat
    15541 ataaatacaa aacaagttat agtcaataat aataaaaatt ctattaatgt aaatagttaa
    15601 tattatactt cctctactac attatctata ccttccttaa catttttttc aactccaaaa
    15661 atatatgtca taataaatgg agcaaccaat gctataaata taactataag tccatttact
    15721 atatttgaaa tccccttttc ccctgataat ccaagtactg ccattatact attttgtgga
    15781 acatataaag tcacatgagt aattcctgca aataaccctg cgattcctgc tcctatagat
    15841 gctaacatag caggtttttt aagtttcaat gtaactccat aaagagctgg ttcagttata
    15901 cccataatag ctgatatcca tgcagctgat gctaactgtt tcatcttact atctttgctt
    15961 cttaatgcta cagctaatgt cgcgccacct tgcgctaaat tagcacaaac ttgagatatt
    16021 aatattagcg attcttgtcc tgtagttgca aatgctgata tgaatatagg agtcaatgca
    16081 tgatgcatcc ctgtcataac gataaatggc attgcagctg ctaataaaca aaccattata
    16141 aatcctaacc ttccttgtag taaatttatt atactagcta atccctctcc taagaaattt
    16201 cctattggtc caattactat taatgctatt ggcgcactta ttaataatac taaagttgga
    16261 tttaaaattg tttttaacat gctaggtgtt aatttatcaa tgaatttttc tatatatgac
    16321 atcatccata ctgttaaaag tgcagggata acagatgctg catatataac accttgaatt
    16381 ggtattccta taaatgatat agggtcccca cttgataccc atgcagagaa atttggatgt
    16441 aaaaacacac ctactactat aactgctatt gatgtattaa cattaaattt tttagctgca
    16501 tttattgcaa gtattatagg cataaagtaa aatgctacat ctcctattat atctaatact
    16561 ctatatgtac ttgaatttga tgatagccaa ttaaaagtgg tgcaaagaga taatataact
    16621 tttatcatcc cagatgctgt aagggctggt atcataggtg tcatacaacc agttattgta
    16681 tctattatat tatttaaaat actatttttt ttatttttat tttttatatc gcttttaata
    16741 tctcctgtgg tatttatccc cttatttatt attgcattaa atacaacacc tacctcatta
    16801 cctattatga cctgatattg agttgaagtt gagtttactc caactacctt atctatagat
    16861 tttaatttat ctgcattgac tttcttttca tcttttaaga tgaaccttaa tcgtgtcata
    16921 caatgagtta agtcaattat attatccttt cctccaagtc catcaattat caattgagct
    16981 acatcttcat atttattctt cataccttat cctctctttt aaaataattt ttaatctagt
    17041 tttaagccaa attaatcttt ttactccaag cttgtaatag tgtattgtaa tttaataagc
    17101 tagtatcttc tacaatatgg tcacattttc ctagtacttc ttttttcccc acaccaattg
    17161 atgtcatatt ggcagcattt atagctttaa tacctgaata agaatcttct attcctacac
    17221 aatcatattg ttttaaattt agcatcttgc tcccttcaat aaaaatatca ggatatggtt
    17281 ttcccctttc taataaggat ggatttacta tacaatcaaa ttcatctttt attcccaaag
    17341 attctaatat cctaggtgca ttcttactag cagatgctat tcccaatttc acattatttt
    17401 ttttaagttc ttttataagc tcatttatcc ctggtaatat atctttatat gttaatgagt
    17461 ttattaactt tatataaatg ttattttttt cttcacacac ctttaacttt tcctctttag
    17521 tataactatc tactttatta gcagataaca atattttatc taatgattct tccctgctta
    17581 tgccttttaa tttttcatta aaagtttcat ctatttctat atctagcgat tttgctatct
    17641 catgccaagc ttcaaaatga tacttagcag tatctgttat aactccatca agatcaaata
    17701 agactgcttt catattaatt actcccttta aaacaattat taacttctat tatgttcttt
    17761 gataatttta tttctttatt atcatgtaat atggttatat ttctaccttt gattaactta
    17821 taataagatt tatattcttc tatatttaca gaaactaaat tatctctaaa taatatatta
    17881 aatttaatat ttttccagtg tttaggtatc cttggttcaa aacttaattt atcatttttt
    17941 attttcattc ctgcaaatcc atatactaaa ctcatccatg ttccacccat attagcagca
    18001 tgtattccat cacttgtatt tttttgtagg ttattaatat ccattaatgc tgtgtccata
    18061 aaatagttat aagctttttc atgatttcca atttcacttg ccatcattcc aaatattgac
    18121 cttgacaaag atgaatcatg agtagttatt ttttcatagt attcaaaatc tctcttcttt
    18181 tgttctaagc taaactcatc agggaaaagc aacgctgaaa gtacagtatc tgcttgttta
    18241 tttacttgat atctatatat tgttaatgga tgataatgga gaagtaatgg atatttttct
    18301 tttggtgtat ttttaaaatc ccatactgat ttttctaaaa atgaatcgtc ttgtttgctt
    18361 attttcttct cttcatcata tggtaaatac atattttgag cggcatttat ccagtttttc
    18421 acttcatatt cttgtaattt aacttttcta aatacttcat ttgaaaataa attatgctta
    18481 aatttatcta ccatctgtac tgcatatatt aaattatact tagccattaa attagtgtag
    18541 taattattgt ttactattgc tgtatattca tctggtcctg ttactccatt tatacagaat
    18601 ttattatttt ttgattctat ataatctcca aattcaaccc aaaatcttgc tgtttctata
    18661 agaatttcta agccattttg catcataaat tcttcatcat tagttgcttc aaaatacgtt
    18721 ctaataccat aagctatatc tgcatttata tgaaactgtg ctgttcctgc tggataatat
    18781 gcactgcatt cattaccatt tatagttctc catgaatata agcaaccttt atttattcca
    18841 agttctctag ctctttctct tgatgcatct aaggttgagt atctataatc taataaagct
    18901 ctagcaatgg atggttgagt atatataaaa aatggtaata tatacatttc tgtatcccag
    18961 aaataatgcc cctcatagcc atcacctgta agaccttttg ctgatatatt agtctttcca
    19021 tctcttcctg ctgattgata aatatgaaat aaattggttt ttatccccag ttgaagagtt
    19081 ttatcgcctt caatctctac atcagaggtt gtccaaaact cattcatttt ctttctctga
    19141 atatttttga ctttatcaaa tccaatatta catgcttctc ttaaaaccaa ttctaatgat
    19201 tttaaatgtg cttctgattc taaacatttt aacgactcca gacattctaa tgattttaaa
    19261 cgttcttcat ttagatttaa atcagaatat actctactat agcctacaac aatttctaaa
    19321 tttaaccttt catctttttt ggcatagact tctatttctc gctcaataca ttcatctgaa
    19381 acattatagg tctcatttgt aatatttcca caagtaatat atgaatcaaa cccacaccat
    19441 aaccctaatc tacttctttc tgtaactaaa ttcataaaat acttattgtt atattttttt
    19501 acatcaattt taaattgctt cttatttata gatgccactc ttgggtcatc tactttttca
    19561 caattaaact tctccatact attttccatt ttatttttaa attttatttt tccattaaaa
    19621 ttcaatggtg ttattgtata tgaaatcatc attaattctt ctatatcttg tgatactaat
    19681 ctttctatag atactttaac ttttctacca caagagtttt cccatataaa tgaacgttta
    19741 agaatccctt catttaaatc tagtatccta gtatgttcac ttgtaatacc ttttgataaa
    19801 tcaaaataat ctccttcaat agagaaattt actatatgag cattaggtaa cttacagata
    19861 gtctgatttt gttttgcata gccataagcg ctttctccat atgtaattgg agattcttca
    19921 taaaatccat ttacatatgt acccatatta tctacatact cattattaaa atcagactct
    19981 tcaatattcc ctctaactcc taaatgtcca ttagctagtg taaacagcgt ttcattggat
    20041 tttattgtat ccttactaaa cccttgctct ataagttggt ccttagtagt aaatattaaa
    20101 ctcataataa cactcctttc ttaaaatgaa ttatgcatga gtttccatat cattaaataa
    20161 aatttctcca tctgtttcta ttactttttt ataccaaaaa gcactttgtt ttttagttct
    20221 tttaaatgag cctcttccat agtcatcaga atcaacatga attatgccat atcgttttgt
    20281 catctttcct tcacttacac tggttacatc tatacatccc cacataagat atcctataag
    20341 ctctattcca tcttcattta ctccaagaat catattttta atatgttctt tcatgtaatc
    20401 tatacgataa tcatcaatta tttttccatc ttcatttaca atatcttgag tacccagtcc
    20461 attttctact ataaataaag gtaactgata cctttcatat aactgattca tagttattct
    20521 taaccctaca gggtcgtttt gccatacact atttgatttt ggaagatatg gattttttat
    20581 ggtttctggt ccgtttgcct ttgatttttc taaaccttca gctctagctg aactacaagc
    20641 actagaataa tagctaaaag atacaaaatc tacagtatta tccttaagtg ttgataaatc
    20701 ttcctctttt attattaatt ttattttatt tgattttaaa taataactca taaagcttgg
    20761 atacacaccc ctaacttgaa catcagaaaa aaacaaatta tgcctttcat gctctaaagt
    20821 tgcaaataca tcttctggtt tacatgtgta tggatatgtt tttccagcag ctaacataca
    20881 cccaaactta aattctttat ttatatacct tcctatttct atagtttttg cattagctaa
    20941 taattgatgg tgtgctgctt gatatttttt ctgaagttga ttttcatcag ctataaaagt
    21001 taacccagca cctatatatg gaatatgcat tatcatattc atttcgttaa aaggaatcca
    21061 gtatttgaca tcatctttat atcttttcat caaaatttca gcatatttta catataaatt
    21121 aaccactctt ctatcagccc acccagaata tttttcaact agagaataag gtatatcaaa
    21181 gtggcttatc gttattaatg gctctatatt atattttttt aattctttta ttatattatc
    21241 ataaagttgt aatccctttt catttggttc actttcttct cctgttggga atattcttga
    21301 ccaagatata gaaaatctaa aacatttaaa acctatttct gctaacattg ctatatcttc
    21361 tttgtaattt tcacaaaatt taatccctat atgacttgga tagtattgat tattttcatt
    21421 taaaatatta tcctcatcta aacatacatc ttttaatctc ttatcattta atggtagttt
    21481 atcaaactga gataaacctt ttcccccatc taaataaaat ccttcacttt gattggctga
    21541 aattgcccct ccccataaaa aatctttccc taatttcatg catctacctc tttcacaata
    21601 taaagtttta taatttctat ctcatattta gttataagat ttttttcata ctataccttt
    21661 taaataattc aatttaaaaa tccaattata ttttttactc actataatta atattgtcta
    21721 ttttcaatac tttcatatta aatatcaata ttagatatct atgtatataa ttatatatat
    21781 agcaaataca tttttatatc ctcattattg ttatcttatt ctcatatatt gctgtatatt
    21841 tatatatata aaaggattta tttcgaaata gaggttgtat tgagaactaa aatttagact
    21901 ttataaatga atggaatttt cattgttgaa atactgaaaa tatatttgat ttcatataaa
    21961 agaaagtgcc tcatgaacta agttcatttt gagacactcc cttttttctc caagctatta
    22021 tatctttttt taaattctaa tggagagact ccaatttttt ctttaaatac tctgtaaaaa
    22081 gtttttgtac ttccaaaacc aacttcttca accaaatcta caatggatat attgttatta
    22141 agtaatatcc actttgcttt ttctaatcta tattcattta aaaaagttat aaatgttttt
    22201 cctgtatttt ttttgaaaaa tttagtaaaa taatatacac taaatcctac ttcataagac
    22261 acatcttcta attttatagg ttgtttataa tttttttcta catatttgaa tatattgttc
    22321 aatctctcta atatctcttt agagtttatt tcatattcta ctgtattttc ttcaatttct
    22381 ctaggaatct gtctatataa tataggaatt aaattataca ttttaccttt tattgcataa
    22441 ctatatcctt ctattttgta taggtcttca ttgtagatat ctatcaatat atcgaaaact
    22501 gactttctta tttttgctga ccaatctcta ctacattttt ttatactact gaataaatta
    22561 attaagcttt ctttttcctc atttaataaa attaaatcat taaaaaaaga tatatcaaat
    22621 tgaaatacta atctttcact tcccggtgat ggcagtatat aatgaatatc tcctcctttt
    22681 attatcacta tctcgccttt ttttaattgc ataggcttgt catttataaa tagatttact
    22741 acaccttctg ttataagtaa tatttctatt tccttatgcc agtgtggtgt tgttaatact
    22801 tctccttcat ttgatagact acgaaaagga aattcatgta ttaatttagg catttctaaa
    22861 tatattgcca tatatatcct ctcctctcta gtgtctaaaa attaatctat actatttaaa
    22921 agaatacaca ttttatttta aaaacctcaa atttataatt tatacaatac ctacacttca
    22981 taaaatatat ctaatatttc tttttttgta tgtgcattta aaagtctttc acctatattt
    23041 ttaccaccta aaatgtaagc tattttagat attaatatca tatcttcatt gcctccagat
    23101 tgtggcatag caaacataat tattactttt acaggtaagc catctatact tggccaatct
    23161 acaccttttt tagatttacc tattactaca gaggccttct ttacatattt tgtttttcca
    23221 tgtggcatgg ccatttgata acctatacta gtagagccta ttttttctct atgttttaat
    23281 gcctttataa acttactttt taaagttata cttcctgtat cgtataattt atctactaat
    23341 tcctgtatta tgccttcttt tgtagttgat ttcaaatcta aaataatgct ttcttctgtt
    23401 aatatttctc taatttccat ttgttttctc caatagatta ttcttaaata atattttaat
    23461 atcctctttg ctcttgcaat ctattatata gtttatatag ttcttttgcc tatataaatt
    23521 tgatatttcc attaaaatat tctttaaaaa actttgatta ctaatttcta aataaatatc
    23581 aatcgttcta gtaacattat tgatattcat tatcccttta tttaatttac tttgcttatg
    23641 tatatatata tttaaatctt ttcctaatga aatagattca tatttactcc ctaaattcac
    23701 acctattaaa ctttccatct gagctacatc aaaattaaaa tatatattat cttctaaata
    23761 cattcctaat aagtttgtat ctaagttcat acttttttta ggtttagaaa gtaaagcatt
    23821 ttttatatta ttaatatcat tttccattaa tagtactgat acaactatat gtaatttatc
    23881 tttcaaatct aagtttacag tagatattac aaagtctaca tcatctaaat ttcgcttact
    23941 caactgatgc ataggaacta tatcaactat agtccattca ggaaattctc tttttaatct
    24001 ggctgcaagg agctgagatg ttccatatcc tgtatgacaa actactatta ctcttttact
    24061 actcatattt ctttctattg ccgcttgaaa atatgtggca agatacgaga cttcatctat
    24121 actaatattc ttcaaattat catactctgt cataatattt atagtcatca tacataatcc
    24181 cagcacatct gaaaatcgct cttgtatctc tcctaacaac gggtttttta tttggatatc
    24241 atatcttaat ctgtttaaca taggccttac atgagatgct agacttttct gtagtaagtc
    24301 atcatttttg agatttatat ttaaaaatcg tgacatattc tctatcatta tagatgaaac
    24361 tttttcactt tcacttaatc tatctgattc atcattgtaa ctactattac tttcgctact
    24421 aaatccagat gataccaaaa aaatatatat gtacataagt tcatctttcg ttatttttac
    24481 tctgtatcta ttttctattt tatctataag tgtagtgaca tttttatata ctaactcgtc
    24541 caaattatct acagaaattt ctctttcttc ctgagattct atttgattac cttcttcgat
    24601 tctctttaaa catataagta tatgggtaat taaatttata tagtagggct gatttatagt
    24661 atatcctaaa ttgtattcta attctgtaat tatagtttct acaaatataa tagaatcaat
    24721 atcaaataaa tttatcaatg cactaaatgt agcagaatct aatcttgtta actcagatat
    24781 atcatgttgt tcataatttt catctaataa atcatccatc attttggcaa tcgatttcct
    24841 tatatccact tctttaccta taatcttagt tccttctaaa gttttattaa gttttaaatt
    24901 gtattctttt atccatgcct ctatatattt aaaatcattt actatagaag ttttacttac
    24961 ataatattta tctgctaact gatttattga agttatatta tttgaattta gtaataaata
    25021 ctttaaaatc tccattcttc tctgctctac tgataaagat ttattttcct tcgattgtat
    25081 atttaaacta ttaattaagt ctatgttctt ctttgctaaa tcttctatta atattccata
    25141 gcctcttttt atatcaattt ttatattaaa agtttctaaa tatttctcaa tcatcttcaa
    25201 atctttttgt aaagttttat cagatacatt taatttatct ttaaagtatt ttataggtct
    25261 atatttattt tcgtttagta tcaatttaag aaattcaatt tgcctcgaca caagcatact
    25321 tagccctccc tacctatgtt tatatatttc tatgtttata ttaagtacta ttttaacata
    25381 tttactaact atgtaaaatt actaagatac ttctgtatca taaaagaatt tatgatacac
    25441 cttactaaat tgatataata gataatataa tttcaaaata aaaattaagg atatttagaa
    25501 gtagttaact gattctaaat atccttatta ttattctata tacttgttgt tattccatta
    25561 attattttta ctattattta taatttaagc accaagtaat tcaacttcac tattttcact
    25621 ccttatagta ggctttgtta cccctataat caatgctgtt attactgtac caatcaatat
    25681 acaagctata tatgcaactg gtgcactaca tgcaaatggt attacaaata ttcccccatg
    25741 tggtgccatt aaagttatat ctaaactcat acatattgcc ccacctatac aagaaccaat
    25801 tatatttgct ggaatcattc ttaatgggtc tgcagctgca aacggtattg cgccttctgt
    25861 tatgaaagat gcccccatta tagcagttgg tagagatgac tttctttctt ctttagtaaa
    25921 cttatttttg aatattaaca tagccaatga tattgctaat ggaggtacca ttcctcctac
    25981 cattaatgct gctgatggtt caaatatatt acttgaaaac atagccaatc caaaagctga
    26041 agctgtttta ttaataggtc ctcccatatc tgatgccatc atccctgcta atattgcacc
    26101 taataatact ttattagttc cagacatact ttgtaaccaa gattgtaaag cttcatttaa
    26161 ccatgatgct ggcgtattaa ctacaaagaa cattatagct ccactcgtaa atgcaatcaa
    26221 aagtggacat atcaatacag catttactcc ttttaataca tctggtaaat tttctgttat
    26281 cttcattact cctaaagcta tatatcctgt tgcaaaacca gctaccatac cacctataaa
    26341 ccctgaacct ccaataactg ccataaaacc agctatcata gcaggagcaa atccttgtct
    26401 tcctgctatt gatttagcta taaaaccagc aagtatcggt ataaataact taaatgctga
    26461 atcgcctcca agttgtccaa agaatccagc tatagggttg tatgtttcat gagttgggtc
    26521 tgatgcaaat ataccaaaca taaaagctat ggctatacca attccaccta tcactacaaa
    26581 tggaatcatt tcagatacac cactcattaa gtgcttataa acaccctttt tctctgaccc
    26641 ttgaagcatt tcttttgaat cttctaaagt ctttccacct ggtttaattt ctttagccat
    26701 tccattttca gcgtttataa ttaaattttt agctaatgaa acattcttag catctactac
    26761 tttcttttgt agcactttct ttcctataaa tctactcagt tgaacttctt tatcacaagc
    26821 tattattacg tattcagctc tttttatatc ttctttagtc aacttatttt ctacacctat
    26881 agctccatga gtttctattt taacttcata tccaagttct tgccctgctt cctctaatgc
    26941 tttttttgcc ataaaagtat gagctatacc tgttggacat cctgttatcc caactataag
    27001 acctttattt tgattattac taaaatctcc tgattctgca gctttattat taaatatact
    27061 taatatttcg tatggagttt ctgcacttag tagatgctta agaaaatttt cttccattag
    27121 atatgtagct agtttagata taatcttaag atgttcatct gaacctgatt ctggaactgc
    27181 tatcataaaa aatgacctaa gtttttgacc atcattatct gtaatctctc tatctgttct
    27241 taaatacatc attacaggtt gatttactac atttgactta gcatgaggta tagctattaa
    27301 attacccata ttagttgatg attctttttc gcgtttatta atatcagcta taaacttttc
    27361 tttattattt atataatttc catggtacaa atgatttgcc atataattaa ttacatcttt
    27421 ttttgtttgt aattgtttat ctagtacaat acaatcgctt cgtagtattt tacctatcat
    27481 aaattctccc ctccttttaa tttgttacct cataattaat ttttattttt ataaaagcac
    27541 tttaacttat ctatagcatt gaatagattc attttaaact ctataacttc tcttgcagat
    27601 tttatacatg gtggatatat agtatctggc tcatataagc ttgggttttg ttctaatagt
    27661 tctctgcact tcttataata tgccgactta acatcactcg aaatatttat tttacaaact
    27721 cctagtttaa ctgcttgtgc tatttcttca tctggatttg atgaaccacc atgaagaact
    27781 aaaggtatat ctactacttc tcttatttct tttaataaat ctagtttaag ctctggttta
    27841 aaaccttttg gatatatacc atgtgctgta ccaattgcaa tagctagtgt gtctactcct
    27901 gttttttcaa caaaatcctt agctaatttt gaatctgtat atattatttc atcagtacca
    27961 ccttcacttg atgttcctgt tgttcctatt gttccaagtt ctccttctac ggacacattt
    28021 aatccttttg ctatttctac tatttcccta gatatagcta cattctcttc atatggtaaa
    28081 tgtgagccat caatcattac tgatgtaaat ccacatctta ttgcccttaa tatttgttct
    28141 ttattttccc catgatctaa gtgtattacc ataggtactt tactcttatt tgcttcttct
    28201 atgcaactag ctacaaagct atctcctaga aaacttagct catttgggtg tattgcaagt
    28261 attactggtg catttttttc gttagcactc tgtactactg ctttaagtat ttgcccactt
    28321 cctatattaa atgctggtac agcaaattga ttttcttgtg ccacttttag catttccttc
    28381 atatttatta acatattgta cctcccgata ttttaaattt taggttgaat ttgcttcttg
    28441 ttaattttgt tgttgtttat atttaaataa tatcagggta atgaagatca gaaaataaca
    28501 atcgttttcc ttagtgaaaa ggaactttta ttatacactc taagttcctt ttcactaaat
    28561 aatttttaga agtctgcatc atagttaatt atatttctca tatacatctt ctctttttaa
    28621 gtgttttatg ctttagcctt cttaactctt tccaataaac aattagatag tttagctata
    28681 aatttaaaga tattcgtatc gtagttagca ctatattgga atcaaaaaaa ttaaaaagat
    28741 actagatagc agataccaat tattaataca ccataagtca tagatacttc tatcttaaat
    28801 tcttgcatat tagttacaat agaaattaaa taggactatt ataaaaatcg taaggtaaga
    28861 ctgacattta ttctccaact atacaaatga atactaatat agctccttct aattaaatca
    28921 tactatataa atcatatata tcccaatttt taaccttacc tctttatatt tactttttaa
    28981 taaaaaaaga tattgactaa atagtcaata tcttttagtg gatttaaata cccacgattt
    29041 taatctaatt tttaatggtt tccttaacat aatcttataa atattaaaat ttatctacct
    29101 ataaaatttc tccattaaat tttattacat ttttatacca atcaaaagat ttctttttat
    29161 atcttttaag agtcccactt ccatcattat ttttatctac atatataaat ccatatcttt
    29221 ttttcatctc tcctgttgta aatgatactg gatctataca tccccaaaca gtatacccta
    29281 taacatcaac accatcaatt tcaatggcat ttttcatttc ccttatatga ctagccaaat
    29341 actctattct ataatcatca tctacagtat tatctgattt taatacatct tctgctccaa
    29401 atccattttc aacaatgaat ataggaagtt catacttatc atatagttga ttaaggtaaa
    29461 accttagacc tacagggtct atattccatc cccaatcaga aatttttaag tatggatttt
    29521 caactacatc agcctttcct gccgagtcat tacctgttgt tttcatagtt ttatcagctg
    29581 ttactacagt agttaaataa taactacatc caataaaatc aactattcct tcttttagga
    29641 tttttttatc ttcctctgta atatctaaat tataattttt tctttcccat aattttagtg
    29701 tatgtcttgg ataatgacct cttacatgta catcagtaaa cataagttgt tctctattag
    29761 attctacaaa tttaatcata tcctctggat tgcaagaata aggataactt ggcatagctg
    29821 ccaccataca tccaatttta aactcagggt ttatttcatg acctatcttc acaacctttg
    29881 cacttgctac aaattcataa tgaactgctt gatacataac ttcttctttg tcttcctgct
    29941 cttcatagat tattcccgag ttagtaaatg cataaatagg atttgtagtt atactttgat
    30001 tatttatttc attgaaagtc atccagtact taactttatc cttgtatcta ttcattacca
    30061 cttcacagaa gtttacaaag aaatctatta attttctatt tctccatcca ccatagtttt
    30121 ttactaaatg ataaggcatt tcaaaatgac ttaaagttat tactggctct atattgtatt
    30181 ttaataattc atcaaataaa tcatcataaa atttcaatcc atcttcattt ggagttgatt
    30241 catcgccctt tggaaaaatt ctagtccaag caatacttgt cctaaaacac ttatatccca
    30301 tttcagcaaa taatctaata tcttctttat aattttcata aaaattaatg gcttcatgat
    30361 taggataatt taaaccctca attactccat ctgttatctt tcttgaaata gtatgagtac
    30421 ctgcagtcat cacatctgca atacttattc cttttccacc tttattatat ccaccttcaa
    30481 cttgatgggc agcaactgcc cctccccata aaaattcttg attagatttc atagaaatat
    30541 ctcctccagt ataattaata aacaactttt attacaggcg ttccaatttt aatatgttta
    30601 ttttctttaa ctattacatc tgctaaatca tttgtgttag ttagtattat tggtgtaaca
    30661 atactatacc cttcaccttc tattttatcc ttatcgaaag aaacaatcct atctcctttt
    30721 ttaactttat ctcctgcatt catatgagta gtataatact ttccatctaa catagtagtg
    30781 ttaagaccta cgtgtattaa tatttctaca cctttatcag aggtaattcc tattgcatgc
    30841 tttgtaggaa aaatagttgt tattgttcca tttacaggag acacaacttc tccctttgaa
    30901 ggtattattg ccatgccatt acctatagtt cctgatgcaa acacttcatc ttctacttca
    30961 gataactcta tttgtaagcc ttctattgga gataatatct cctctatacc atcatcttca
    31021 tcaaaagcaa cttcttcatt accttcttca cattcttctt tactcaatcc aaagaaatat
    31081 gacaatactg ctcctagcac taatgctgtt cctattccta atatatatcc taggaatggt
    31141 gtataaactg gcattgagaa tatattatga aatacatatg cattacaagt aacaccaaat
    31201 acaccacata taccaccacc aatacctcct gcaatagcca atactggaat cattcttctg
    31261 tatcttaata taattccata aattataggt tctgttactc ctgctaaaat tcctgtaact
    31321 gctgttgaac ctgctaatac ctttaattct gaattttttt tagattttct aaccttcata
    31381 aataaaccta ttgcaatacc tatttgagca aatactgctg caacagctgc accttctatt
    31441 gggtctccac ccattgtagc caagttttgc aaagtaattg gtgtgaagcc ccagtgtagt
    31501 cctaatactg ctaagaatgg catagctata cctattgcag ctcctgcaat tactctgtta
    31561 aattcaaata atcccataaa aatattagat attatatcac caacattagt tgctattggt
    31621 ccaaataaaa tcacagttaa aggaaccatg actaataatg atatcatcgg tactaagaat
    31681 aattgtaaat cctttaatat aatcttcttt aaaagcttat caacatagta ataaataaat
    31741 atagcaacaa atatagggaa tacaccaaaa gaataatcaa ttgctgttac tggcatccca
    31801 aaaaagttag caccaccttt tgctccaatt aaagctgtaa aattaggatc taacaaagct
    31861 gctcctatca ctccaccaac atatggattt gcactaagtt ttatagctaa ggtaatacct
    31921 aagaatattg gtaaaaagta aaatacagca tttccagctg ctgataatat agcataagtg
    31981 ctacttgtat cagacatcca tttcatagta gttagtattg taagcagtgc cttaatcatt
    32041 cctgctccag ctagtgcagg tattaatgga gaaaatgcac ctgaaattga ttcaaatatt
    32101 ttagaaacta ttgaaacttt ttctccctgt tcttcagtat tttgtccttg taaaactgct
    32161 ttttttataa tagtttcaaa gtaatcagtt actttatttc caattaccac ttggtattgt
    32221 cctccactat ttactacaga tagtacatcc ttcattttta ataactcttc tttgttagtt
    32281 tttgaagtat ctttcagctt aaaacgtagc ctagttgcac aatgaactaa actaataata
    32341 ttttcttttc ctccgacata ttttataatt tcttcagact ctctttcaaa tttcatacaa
    32401 tctatcctcc attttcataa ttttatgtat aaaaatagac ctaaatcaat acaattagat
    32461 attaaaaact aattatacca acttaggtca tgcctgccaa acagtaacaa tcctacacta
    32521 tttactttat atttgataat ctatttaaat gcaatgttaa gtacaacaat tcattttcgc
    32581 taattttcca tttatacgtc ttttcaagaa agttttttac tttttttgca caattgtaat
    32641 cacttttata tttcattttt attatatcta acaatgatgt gtctacattt gtattctcac
    32701 cacttaattg cctttttata aaacatctta aatgacttat aaaccttgtg tagtcaaagg
    32761 aatattcatt tatttcgatt ccatagtgat actttatgat atctaataca ttatcaatta
    32821 tcttagttaa caataaagtt tcttgcatat cttttgtttc taactgagca tttgcaaagt
    32881 gtatcgtaat aaatgctatt tcagaatcag gaatattttt atctaatttt tttcttaaat
    32941 attctacagc tttcttacta aaattatatt cattaggata tatttgtctt atttcccatt
    33001 gaagcgggct ttgaaatact aatccttcat ccattctttt taacatataa cttatatgtt
    33061 ctgataatgt gattaatata ctatcattaa gattatcacc caattcttct cttcccattt
    33121 gaataatttc acttacaagc tcaacatctt ttaaaggtat cctatctagt agtgaatgta
    33181 attcacttaa tgattcctca ttattgaata taaatttctt ttcaatttta tctatttcaa
    33241 ctaaatcttt agtaaattta ttaaatccaa ttccttttcc cattaatatt acttcttgtc
    33301 ctgaattatc tctggcaaat acaacattat tattaaatac tttctttata accataaact
    33361 acctccactg taaacaaaaa gagacctaaa aaagactaat aatactttaa gcatttacta
    33421 gaatttttag gtcacgcctg attacatcta tctcagtaac gatccgttta tttatctgta
    33481 tgataacttt attttcatta taaaataata actgtactta gtcaatatat aatttcatgt
    33541 atatctctac tagattattg tcataagtat tcactcattc tacttttttt atatgattta
    33601 tataatctaa acatgctaaa ataagttttg aagttatttc ataacaaaat taaggtcata
    33661 tattttttat tatatatact cgattattta tccatatata aggaaatcct ttattttgta
    33721 actacaataa ctgcctaagt tttgattttc ttttatcttt tacttctcct tattaaaaaa
    33781 taattctttt actgttgtat ctaaggctct aaacagttta atcatcaaat cattgtttgg
    33841 attattaacc ttacctaact tactatatag ctttttaact gtatatcttt aatagacctt
    33901 ttggtatgct aatccatttt ataacactaa ttcttgaatc aagcatatat tacccttaca
    33961 aagcatatct tataccctct gtagagttat gatagttgat gaacctgaag aaattaccct
    34021 tacaagacat atctgataca acctcactta ttagtttata tgtttcagaa gtatataaat
    34081 aacacatact tacttccaaa ttcttaactg ttttcttaga aaattctaat atgatttcct
    34141 tacatagcga ttataacagt gtcttattag atttcataaa attatacatc ctctttacat
    34201 ttaaacttta aatttttatc tattgtttat taattaactg tatattcact attttttatc
    34261 atttataata ctcttcttat tatcttaaaa caattataat ctaaccttaa tcacatatta
    34321 tataaatatt tttaataaac ttaataatta aataactata tttcattatc catcttataa
    34381 atgtttataa actttccact attcttcttc aataaattca aacaaatttt ctactgtagt
    34441 atcgaatact ttagcgatat ccatagctaa cttcaaagaa ggattatatt tcccattttc
    34501 taagtgtaca atagtctcac gtcttacccc aaccaattta gcaagttcat tttgcgtcat
    34561 aaggagtttt tctctgtatt ctttaatttt tgttttcatc aatattgcca cttagttaca
    34621 tatccccctt ttatcaaagt atatatacaa cactaattta gataaagact gtataaataa
    34681 aactgcaatg aggattatac ctgtatctag gtttgatata tttatattac ttgtataagg
    34741 tgttgcaaag aaaatagata ttattactat agaatatatc attattttta ttgcaatctt
    34801 attaaccttt gatagtataa attcagatga ttcatcaact aaatcattat attttttatt
    34861 ataaattgaa taacatccaa aaactattaa ccaactcaac cctggaagag aagcagtgct
    34921 tggaccttta aaaatatatt tagtagctaa tacagctata aaaaaataag ttattacaag
    34981 taattccaag atgagctttg atcttacacc agtttctgat ttagacatat aaaatcactc
    35041 cttaaaagtt atatattctc tatatttttt aatttttgtt ttcataaata ttattactta
    35101 gttacatatt ccctttttat caaaatatat atacaaaatt aattttgaca aagattgtat
    35161 gaataaaact gctaagagca ttatacctat atccaaattt gatatgtcca aagctcttgt
    35221 atgattaact gaaaagagaa cagctattac aaacatagag tataacatta tttttgatgc
    35281 aatctgatca acctttaaca acataagttt tgatgcctca tcaactaaat cattatattt
    35341 tttattatac atgagattgc acacccaaaa agctaataaa attataaaag taaaccaaat
    35401 accttctcct ttaaaaataa acttttgtaa taacaagtct ataaaaaaat aggatagcat
    35461 cattaactct gaaacaagat ttgccttaac accaagctct gatttagaca tataaaatca
    35521 ccccttaaaa gttatatatt tataacacct tatgttataa atatataact tttccaaata
    35581 aattgcaata gaatattgaa aatattcaat aatatcttca taaatatatt ttataaaaga
    35641 ttttataata aacattacaa tacagtacta aattagttta tttcatctat catctcaatc
    35701 atatcattta ctaactatta ttctaatgag catataacat tgaaatttat aattatacaa
    35761 cctaaatgcc tcccaatgta ccctcaaaaa catcatttcc tgtaactgaa gtataattgg
    35821 tatattttat cactgaaata aaaaaacact agtcaataaa gactagtatt ttcaagtatt
    35881 ttatcattct ttttttaatt attggagacg aatcatcaga ataatgccca taatttatct
    35941 atatgcaaat tctaaattta aaataaagtt tcagatgaat ttactattct atgctatgat
    36001 acaacagaaa aaactgaaat ctatgagtgg tagcttcata taatcctagt tcctacagta
    36061 atcaaaactg aggtttattc tatatgtaac taatgataaa ttttattata ggagttatta
    36121 gctctatttg tgttactata agtagtaatt atatatatga taatttttta acacttttct
    36181 gttggctata tagaaagtgg tttagaattt aaatttaaat aaaatttaaa ttcaccaaaa
    36241 agaaatctat attagaaacc actactctat tccaccagat tgtaattttt tgttctttat
    36301 atcacaatgc tataccatat taaattgaaa aataaatttt aaatttattt gttacaattc
    36361 attaattcaa aaaaatattt tgagtcatga gttttgtaaa gatttagcca tgaatttaat
    36421 gcttctgatt caaaaacatc taaaagtttc aatacttgaa acgtaaattc caacggagcg
    36481 attcctgaag ccgtaactaa attttcatca ctaactacag attccgtttt ataatatttt
    36541 tctccagagt aatttggtat taccatttta agaaactcta agtcattact tgtatgattt
    36601 ctaacatcta atagcccttt tttagctagg cctaatgtag ctccacatat ggctgcaact
    36661 atagaatctt gtattaaagc ttctttaact ttttctaata ttatctcatg attcatggat
    36721 aaccaagtat ttccccctgg caaaattaat aaatccttac tttccatatt aaactcatca
    36781 actgtaattt caggtaaaac ttttaaccca cccattgtta taataggatt tttatcaatt
    36841 cctacagtaa ttacttttag tggctttaat ccttttttaa aatatcttcc tgtatttaat
    36901 tcagcagtta aatatgccac ttcccaatct gacatagtat caaatacata catatatact
    36961 tttctatttt tcatcttttt tactccttat gtaattaatt tatatatcta attataaaat
    37021 aacttaactg acatattcag tcagttaagc tattaaattt gataataatc aattaattct
    37081 agtaaatctt caattatttt cttcctaagg cttagtggtt caattacttg tattgtcttt
    37141 ctataaggta aaagtatatt tggtatgtac ttgcatatta cttcctcttc gagcataaat
    37201 attattttat taggtgttct ttctttcaag tagtgcccta aaaaccaatg ttggcttaaa
    37261 ctatctaaag aatctatact cccttctaca actaattgaa ttatattttg ttcatctttt
    37321 atttcaggta taattccttt tataaaaaat tcacttgctg aaaattctgt cggtctgtta
    37381 aatgtatttg atgtttctat gatttcacta atcctatcca ctctgaaact acgtacctca
    37441 tttctcatat tacaaaatgc aactacgtac caattattat tccagtgaac aattccatat
    37501 ggatttataa ttctatattt tgattttgct ttacgacctg catgatagtt gatttctaca
    37561 gatagctcct ttaatatact attctccaat tttttaagta ctgattctat agacactttc
    37621 ccaattggtt ttattacttc aagggctctt aagtggtttg ttaaaatatc ttcttggttt
    37681 tgatttgaat acatttttaa ctttaatatc gatttatcta atgcttcgtc taagaagtat
    37741 ccttcttttt tagcaaatag agctgcatga agtagagatt tttgctcttc tatatcaaaa
    37801 aaaagaggtg ctttagtaaa attatttaaa aggctatacc caccattatg acctgtatct
    37861 gaaattatag gtactccact cgcagaaagt acatcaatat atcggtacac tgttcttata
    37921 tttatttcta atttttcagc tatctgtttt gctgtaattt ttttgtcaga gtttaacatc
    37981 cacagtatag acatcatatt gtcaatttta gccatgtagt ttcacctctt tctatttgtt
    38041 atataaagtt attatataac tttttgattg attttttaca aaaaaacatt agtaaactgc
    38101 taataattta tactaagatt tatttcaaat atttatagat agtctttttc tatagttaag
    38161 ttatccatta aattacatag tagtatatcc attttagttg atatattttc agctacctcc
    38221 cttgaatatt attacaataa gtctaaatct tctttcttcc ataaatatat tatgaggaaa
    38281 gactatcatc tttaatggtt taatagtata aaagatatta atttaaaaaa atctattttt
    38341 atatcagatg ggtattgttt tttataaaac tgaaaaaatc acctaataga atctatgatt
    38401 ttttaacata acctccataa attagtacca attatcactt caaattcaaa tttttatctg
    38461 aagaatatac aatcatattt ccatactcaa cataatattg agtgtttggc ttgtatttac
    38521 aaattattat tctaacaaaa acaactatac atagattaaa atcaccttct aaacataatt
    38581 attaaaattt aattaatgat atcaattcca ttaatctctt ttaataaaaa attctctttt
    38641 ctatatgaaa attatttcaa aacttttaag ttaaatacaa aaatgactat aaatagattt
    38701 ttatttacac aaatctattt atagtcacta tagtttatcc aataaaataa taaaataaat
    38761 atgtacacaa taaatgttat ttacgtctta agtatttatt tgttagattt ttaattaaaa
    38821 aaaacaagct aatgaacatt aatgctaaat ctagcattat attactttga tctcctgttt
    38881 gtacattttg acctacatta ctatctaaac tttcatctgt atctatattt atatccggct
    38941 ttccatcccc atctgtatct atatttatat ccggttttcc atctccatct atatctatat
    39001 ttatatctgg ttttccatct ccatctatat ctatatttat atctggtttt ccatctccat
    39061 ctgtatctat atttatatct ggttttccat ctccatctgt gtctatattt atattcggtt
    39121 ttccatcccc atctgtatct atatctggtt tgctatttcc tccattatct gggtctggtt
    39181 tactatttcc accgttatct ggatccggtt tgctatttcc tccattacct gaatctggtt
    39241 tgctatttcc tccattacct gaatccggtt tgctatttcc tccattacct gaatctggtt
    39301 tgctatttcc tccattatct ggatccggct tgctatttcc tccattatct ggatctggct
    39361 tatttagatt tggattacct gtatcataac ctcctgagcc agtatctaca tttttatcag
    39421 gcttccaata atcatctact ccatcattat ctgtatctat tgctggacga ttataatctg
    39481 tatcagggtt tccatctcca ttggtatcta tatttttatc aggtttccaa ataccatctc
    39541 catttccacc ttctgtacta ggcttccatt cacctgtatt atcagtatct atgttaatat
    39601 ctggcttcca atcaccactc gtatctatat tgatatctgg ccttccatca ccatcagtgt
    39661 ctatatttat atccggtatt ccatccccat ctacatctac atttgtcata tctaacttta
    39721 acttcttttc atcctcacta ccttcaatgt aatttatatc atctccaata tattttacag
    39781 taatagtttg ttcagtagta aaaatatgat gattgctatc taaaggtctc cattcaatag
    39841 atgcagtact ataattatga ctctcactac ccttattatg agtttttaat tctactggat
    39901 ctttatattc ctttccatta atatagaatt gtacgtaacc tcttggagag gcacaatctg
    39961 gtccttcttt cttatctggt gaaatagtaa catttaatgt aaacgtatct gttggtttaa
    40021 aaacatcagt tttagcttta gactcttcta caactaatga agtttctgta tcagcaggaa
    40081 taatttctgc cttataatat gctctatgcc cccaataagc ttcattaaaa ggatatacat
    40141 ttgaaaactg tgttgatgta atgcttaatt gatattttcc agcatcaact tgctttgtaa
    40201 ggtcatcact tcctaaattt gtatctggtt ccattgtttc ctcatttaaa cgttgagaac
    40261 taatagtcat aaatttttta tctgtgagtt tttcaccttt aggagtaatt attggaatac
    40321 ccccatcttt taatatccaa tctaaaaata atttttctac atcttcttca aatggtaatc
    40381 catcatatct tttaataatc aaatatggtg gagtatcatc aatagtaaat tcttcatatt
    40441 gctttaaaaa ttgagaacct gaacctatat ctttaacata aaaatcatct ggttttatat
    40501 ttcctccagt aattttatct ataacaacta aattaacaga tacttcagat cccttaaatt
    40561 gatcagaaaa ccataagtaa agaacccctt gatcatctgt ataactaggt gctccataag
    40621 gataaatttt tccatcaatt agcattttaa aatcatcaac taatgtagta ctaactttat
    40681 cttgtcctaa atactttaaa gatattttat tcataaaaac ttttgttttc ttttctaaat
    40741 caccgtatgc aactgctcca cctaaacttt tgaatgttgt tgcttttaat gaaccacctg
    40801 ttactataac atctcctgtt gtagcactta ggtcaaaaat ccaatctccc actcctgtca
    40861 tataaggtaa aatcgttcct ccagttacaa gtatacgata tcctctattt gttcctggat
    40921 taacacatcc atccccaaat gcactaccat gtgcacctcc atatgaatag gaaagtccac
    40981 cattaattgt aatatttcca ctataaccag aacctgtgct aggatctact actgagggac
    41041 ttaatgcatt ctttgttgtt gtatagtatc ctccacctat tccagctcca tggtatgcac
    41101 ctttagcagt tatagtacca ccattgattg tgatatctcc accactacca ttaccgcctc
    41161 cacctattcc agctccatat cctgtattac gactcgattc ttgacctata gcagttatag
    41221 caccaccatt aataataata tttcctccac tttcagtatt tccaccgcca atacctgcag
    41281 aataataatt tccaacaact tttaaacttc ctctattatt actatctagt agtgtaaggc
    41341 gatctccttt ttttaacttg tctccatttt ctagagttac atctctagga atttttccac
    41401 cctcaggaac tataaactct ccttcaatat ctctatttac aacagaatca tcaataatta
    41461 gagtagtacc ttttcctgct ctcatacctg gataatatac atcacctgac tctagcttgt
    41521 tttcactacc atcttgtaat ataacatgtg catatgcacc accatcttta tctggtgtta
    41581 aagtaaatgg gctattagat gcagttttaa tatttactcc atcaaatatt aattcagctt
    41641 ttacatcttt aggtataaca atcctatgtg ttgttggagt atttggatta ttattttgaa
    41701 ttgtcatttg ttttccacta agaatagtta aaacgccact tgcaaattta aaatcgacat
    41761 ttatttctcc accactaatt ttaaagtctc ctacagatgt aggatcttct gcagtggctt
    41821 cttccacaac taatgcattc atatcttctt ctgcatttcc tgcattagaa tcttcttctg
    41881 catttcctgc attagcatct tcttctgcat ttcctgcatt agcatctcct tctgcatttc
    41941 ctgcattaga atcttcttct gcatttcctg cattagcatc ccctcctgca tttcctgcat
    42001 tagtatctcc ttctgcattt cctgcattag tatctccttc tgcatttcct gcattagtac
    42061 tttcttctat agtatctgcg aaagtatttg acgcattaaa tgatgctact gatccaagtc
    42121 ccattgagat acttaaaatc attgatagtg ctttcttttt acatttttgt tgcataaatt
    42181 ccccctcccc ttaataattt ttaatataca ctgtatacat ccttatatac actctaataa
    42241 ttcttaatat acactgtata catccttata tgcactctaa taatttttaa tatatactta
    42301 aaacttatat ttgtcaatga atatactgtt tttttcaacc ttatatatta taagtattca
    42361 ttatttgcta aataactaca ataaaaattt taattatata aaat
//
LOCUS       DAEPUT010000032        42015 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.033, whole genome shotgun sequence.
ACCESSION   DAEPUT010000032 DAEPUT010000000
VERSION     DAEPUT010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42015
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.033"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            313..1857
                     /locus_tag="KRL22_001808"
     CDS             313..1857
                     /locus_tag="KRL22_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH1272302.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLIRG"
     gene            2033..2401
                     /locus_tag="KRL22_001809"
     CDS             2033..2401
                     /locus_tag="KRL22_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1272303.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKITLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            2403..3128
                     /locus_tag="KRL22_001810"
     CDS             2403..3128
                     /locus_tag="KRL22_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272304.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            3122..3886
                     /locus_tag="KRL22_001811"
     CDS             3122..3886
                     /locus_tag="KRL22_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272305.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNENTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            4108..5358
                     /locus_tag="KRL22_001812"
     CDS             4108..5358
                     /locus_tag="KRL22_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1272306.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            5549..6433
                     /locus_tag="KRL22_001813"
     CDS             5549..6433
                     /locus_tag="KRL22_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH1272307.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            6795..7412
                     /locus_tag="KRL22_001814"
     CDS             6795..7412
                     /locus_tag="KRL22_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBH1272308.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTTDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIIKPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            7520..10051
                     /locus_tag="KRL22_001815"
     CDS             7520..10051
                     /locus_tag="KRL22_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1272309.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            10485..11186
                     /locus_tag="KRL22_001816"
     CDS             10485..11186
                     /locus_tag="KRL22_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBH1272310.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            11236..12318
                     /locus_tag="KRL22_001817"
     CDS             11236..12318
                     /locus_tag="KRL22_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1272311.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            12579..13679
                     /locus_tag="KRL22_001818"
     CDS             12579..13679
                     /locus_tag="KRL22_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG-Cd"
                     /protein_id="HBH1272312.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDILPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLISDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            13676..14482
                     /locus_tag="KRL22_001819"
     CDS             13676..14482
                     /locus_tag="KRL22_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1272313.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            14500..16638
                     /gene="vanT"
                     /locus_tag="KRL22_001820"
     CDS             14500..16638
                     /gene="vanT"
                     /locus_tag="KRL22_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH1272314.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            16952..17572
                     /locus_tag="KRL22_001821"
     CDS             16952..17572
                     /locus_tag="KRL22_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH1272315.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(17738..18274)
                     /locus_tag="KRL22_001822"
     CDS             complement(17738..18274)
                     /locus_tag="KRL22_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH1272316.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(18387..19061)
                     /locus_tag="KRL22_001823"
     CDS             complement(18387..19061)
                     /locus_tag="KRL22_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBH1272317.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            19264..21138
                     /gene="asnB"
                     /locus_tag="KRL22_001824"
     CDS             19264..21138
                     /gene="asnB"
                     /locus_tag="KRL22_001824"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH1272318.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(21230..22666)
                     /locus_tag="KRL22_001825"
     CDS             complement(21230..22666)
                     /locus_tag="KRL22_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH1272319.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKRSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            22995..23573
                     /locus_tag="KRL22_001826"
     CDS             22995..23573
                     /locus_tag="KRL22_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1272320.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            23612..24190
                     /locus_tag="KRL22_001827"
     CDS             23612..24190
                     /locus_tag="KRL22_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1272321.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            24276..24905
                     /locus_tag="KRL22_001828"
     CDS             24276..24905
                     /locus_tag="KRL22_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1272322.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            24895..27654
                     /locus_tag="KRL22_001829"
     CDS             24895..27654
                     /locus_tag="KRL22_001829"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH1272323.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            27741..29303
                     /locus_tag="KRL22_001830"
     CDS             27741..29303
                     /locus_tag="KRL22_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBH1272324.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEDI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            29304..30440
                     /locus_tag="KRL22_001831"
     CDS             29304..30440
                     /locus_tag="KRL22_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH1272325.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            30504..31580
                     /locus_tag="KRL22_001832"
     CDS             30504..31580
                     /locus_tag="KRL22_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBH1272326.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            31558..32796
                     /locus_tag="KRL22_001833"
     CDS             31558..32796
                     /locus_tag="KRL22_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBH1272327.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            32850..33938
                     /locus_tag="KRL22_001834"
     CDS             32850..33938
                     /locus_tag="KRL22_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBH1272328.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKHFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            33966..34757
                     /locus_tag="KRL22_001835"
     CDS             33966..34757
                     /locus_tag="KRL22_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBH1272329.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYTNIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKCDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(34872..35426)
                     /locus_tag="KRL22_001836"
     CDS             complement(34872..35426)
                     /locus_tag="KRL22_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH1272330.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            35622..36824
                     /locus_tag="KRL22_001837"
     CDS             35622..36824
                     /locus_tag="KRL22_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBH1272331.1"
                     /translation="MKSFVSPDNIWVLWAIVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            36880..37860
                     /locus_tag="KRL22_001838"
     CDS             36880..37860
                     /locus_tag="KRL22_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH1272332.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            38108..39061
                     /locus_tag="KRL22_001839"
     CDS             38108..39061
                     /locus_tag="KRL22_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH1272333.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            39051..40007
                     /locus_tag="KRL22_001840"
     CDS             39051..40007
                     /locus_tag="KRL22_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH1272334.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            40004..40759
                     /locus_tag="KRL22_001841"
     CDS             40004..40759
                     /locus_tag="KRL22_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1272335.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            40851..41816
                     /locus_tag="KRL22_001842"
     CDS             40851..41816
                     /locus_tag="KRL22_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1272336.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT        16353 a         4328 c         7240 g        14094 t
ORIGIN      
        1 ggatagtttt gaaaagaaaa tattaaaatt ataatataaa aataaaattt ttcagacaat
       61 ttaaacaaaa ataatcacct tttaataaat aattatatgc caaaataatc caatttattt
      121 tctattatac ctatatgaaa tgtataaatc aatagttaag acaatgaata tgctacattc
      181 tataattata gtagcagaaa gttttacaaa attaaagtag atataaacta tccattttta
      241 caagaaatgg aaacttttga gatgtactta tttgctaata aaatagaggt gttttaatgg
      301 gaggaaattt ttatgaggaa tttacaaaaa aaattgatgt tttttttatt tatttgtata
      361 attttacaaa ttacatacac aacaccagtc tattctttat gcaaactcta taaaaacaac
      421 tccataaata actttgagtc tattgtgtct aataatcagc ttattagcaa acatgcaata
      481 caaataatac ttattatggc tataatatgt gtaatactta tattctatat aatatatgat
      541 aaattaaatt ttaaaattaa attgcaaagg atagcatata cagataatct tacaggagca
      601 aatactatag ataaatttgt aattgatgct aacaaaatac tatgtaaaaa tactcaagta
      661 aagtatgctt tattatatat agatattgat aaatttaaat atataaatga tttatttgga
      721 tatgaagttg ggaatgaaat tttgcgtaat ttaacaaaga ttattaagag taatatattt
      781 gaagaggaaa tgtttgcaag aatatctgcg gataatttta ttataattat gaaatatata
      841 gaagaagaag atataacaaa gaggttaaaa actatatttg aagaattaga cttgtttaat
      901 aataatcaag aagaaaaata taagttagtt ttaagttgtg gaatctattt tatacttcca
      961 gaagatagag atatcaactc aatcatagat agggctaata tacctcataa aatggcaaag
     1021 ggaggacata aaagttcata tgcattttat gataataaga ttcatgacca agagataaaa
     1081 gaaaaagaga tggaaaatac aatgttttca agtctagaaa ataaagaatt tattatatac
     1141 ttacaaccta agatagaact taatacagga gagatacaag gttcagaagc acttgttagg
     1201 tggaaacgtc ctgataaagg gctaatacct ccaaatgaat ttatcccatt ttttgaaaga
     1261 aacggttttg ttataaattt agatttatat gtgcttgaag aagtatgtat ataccttaga
     1321 aaatggattg atgcaggaat aaatccagtt actgtttcag ttaatgtttc aaggatacat
     1381 ttatattgca ataattttat agaaacatac aaaaatataa ttgataaata caatatacct
     1441 gcaaagtata tagaacttga attaacggag agtatcatat ttgataattt tgatatttta
     1501 attgatataa tgaataattt aaaaaaaata ggatttttaa tatctatgga tgattttggt
     1561 tcagggtact cctcattaaa tatgttaaaa gaaattccta tggatatctt aaaacttgac
     1621 caaaaattta ttatggaaac ttataatagt aaaagaagca aaataattgt tactaaagta
     1681 atagaaatgg caaaagagtt gggtatgaaa gtcatatcag aaggagttga gacagaagaa
     1741 cagtttaaac ttttaaaaga agtaaagtgt gatatggcac aaggatattt gtttggaaag
     1801 ccaatgccaa ttgaagaatt tgaacattta attgtatcca acttgataag agggtaatta
     1861 atctgtaata taaagaattt aataaattgt gttaaaaatg gactctaatg tagtgttcat
     1921 tttttttgta aaatttttta tacttttact aaaaagtaat tgacatatac tttgtattat
     1981 tatattattg tattaacaac ttaatacaat aatataataa ggaggcatga acatggaatg
     2041 ggaacttgat aataacaaac ctatatatat acaattagta gaacatttaa agttaaaaat
     2101 aatttcaggg gaaattaaaa taggatctaa attagaaaca gtgagagcac tagcagaaga
     2161 tgcggaagtt aatccaaata caatgcaaaa ggctctaaca gaacttgaaa gacaaggttt
     2221 agtttatagt cagagaacta aaggaagatt tgtaacagat gataaggaaa aaataaaagc
     2281 tatgaaagag gaaatagcta atgtggagat aaatacatta aaaataacct tagaaaagct
     2341 tggatatgat agagatgaaa tgctaaaact tattacagaa aatctgaaag gagaattata
     2401 aaatggataa aaatataagc aatgtttctc aagatggaat agttgaattt aaaggtgtaa
     2461 acaagagtta tggaactaag aatgttttaa aaaatattga tttaaatata ccaaagggaa
     2521 aaatagtcgg gctgttagga cctaatggaa gtggcaaaag tacaatgatt aagctaatga
     2581 atggattatt acagcctgat aatggtgaaa ttatgataaa tggaatgaaa ccatccatag
     2641 atactaaaaa aatagtttca tatttaccag aaagaactta tttaaatgat tggatgaagg
     2701 tatcagattt acttaagttt ttctatgatt tttatagtga ttttgatgtt agaagagcaa
     2761 atgagatgat taaaagctta gatattgatg taaatgaaaa gctaaagaca atgtctaaag
     2821 gaactaaaga aaaagttcaa cttattttag taatgtcaag aaatgcgagc atatatatat
     2881 tggatgaacc tataggtggt gttgacccag ctgcaaggtc atatatactt aagactatat
     2941 taaaaaatta ttctgaagat agtactttac tgattgctac ccacttaata agtgaaatag
     3001 aaaacatatg tgatgagata atattcatat caaaaggaga aatagtgtta caaggagacg
     3061 ttgaagcaat aagagaagaa aaaggaaaat ctatagatgc attatttagg gaggaattta
     3121 aatgttaggt aaattattaa aatatgagtt aaaagcaagt ggaagaatat ttataccgtt
     3181 atatatagcg atattgatag tagctgtatt taatggaata tttatgaata caaatatact
     3241 tcaggtacag ggaataggaa tactagtatt aacaagtctt tttatggcat taggagtttt
     3301 aactattgta gttacaattc aaaggtttag aaaaaatctt ttgggggatg aaggttattt
     3361 aatgtttact cttcctgtta gcactagttc acttatatta tctaaatgta taacagcact
     3421 tatatacgct gtacttagtt ttatagttgc agtattcact tttggagttc ttatgctttt
     3481 tggtacttct ggaattttac tacctgaaat tttagatttg tttaacacta gttttaaatg
     3541 gatttctgaa aactttttag atattttatt attagtagta gtaatgttta tttcatattc
     3601 atcatttatt ttgttattat atacatcaat ctcaatggga caattaccaa aattcaataa
     3661 acatagaaac atagtggcat ttgcttcttt tatagctata aatatagtaa tatcaattgt
     3721 tggagatgca gttggaagca tcttaccaaa tgaaaataca aatatggtat atcatcttta
     3781 tcagagtcct agttttatgc ttgcaatact tggtagtctt gtagttgcaa tagcgttatt
     3841 tttcgctaca aaatttatat tagataaaaa attaaattta gaataaatgt ttttatatgg
     3901 agctatcttt tgagtaatgt taaaagatag ctcttattat ttatgtagtt aattcatgta
     3961 tataatatga atagtgtttt atttctagtt aaatatatac atatgttgta taatgatatt
     4021 gcgtgtaaaa atttgtaaga ataactatac actttatata agttatatca agaaaattta
     4081 aaaatatatg gatttgaggg agaagatatg aaaagttata caaaggctaa gtggagtgtt
     4141 tggggtataa ttacattttc atttgtttta gtattatttt taaggatgtc aactgctgtt
     4201 gtttcagaca atttagcaaa tgagttaggt tttaattcta tacaaatttc aaatatagca
     4261 tccttttgcc tatatgcata tgcatttatg caaatacctg caggaatttt gattgataaa
     4321 tatggagcaa gaaaaattag cagtcttgga ataataatgg caagtttagg gtcaatttta
     4381 tttggtttga ttcaaagtat agaattagca tatatttctc gtgtaattgt aggggcagga
     4441 acatcagtaa tattactttg tattttaaaa attcaaggga gatggtttaa taagtcagaa
     4501 tttgcttctg caacagctaa attttcattt gtaggaaatt taggtggagt tcttgctact
     4561 tttccacttg tgtttttgtc tgaacttgtt ggttggagaa attcattttt attaatcggt
     4621 ataattggtg ttgtaattgg atgttttatg tatattattg ttagagatac accaaaagag
     4681 tatggattca atgtagatac tgaaccctat gaaaagtcag agaaggttaa tattgttgat
     4741 ggtattaagt ctgttataaa gaacaaatca acatggtata attcaatgat aatgttctct
     4801 tttgttggtc ttacaagtgc atttataagc ttgtggggag taagatacat aatggacgtt
     4861 tatggtgtga gtaagagttt ttctgcgttt atagtatcat tttttacata tggatttata
     4921 tttggttcaa taattatgga ttttgtattt gctaaaataa ggtctagcaa atttaatata
     4981 ataaaatttg gggcaatgat agatttgttt atatggattg taattgtagt tgtataccag
     5041 gtaaaaccac caattatagt tttaccaata tcattcttta ttatgggatg tatagttatg
     5101 tcacatctac aggtttttaa tgatgccaag tataaaaata aagaaattta ttctggactg
     5161 gcaactagtg ttattaatac ttttgaattt ataggaagtg gaattattaa tttgattata
     5221 gctatctctt tacaagtaaa ttcatataat atagttgatg gatataaaaa aggttttgta
     5281 gtatttatag tactaagtat tataactata gtatcatctc atataggggt aaaaaatgat
     5341 gattttaagg ctatatagtg ttttattaat agtttaattt agtattatat tttgcatata
     5401 tataacaaat agtttgcatt ttcctaatat gtataattgg aatataaatc ttgtttacta
     5461 tgtacaaatg gtattgtatt atattaaata gaaaataaga actttaaact ataatattgg
     5521 ttctaaaata taaggtaagg agttttttat ggatacgacg aaaatagatg atataagcaa
     5581 gttagattta aataatttag atattaataa gatggatatg ggaggtataa tggaaagtct
     5641 attagaatgg gctactacaa gcggagtaaa acttataata ggcatactta tactttctat
     5701 tggatttaaa ataataaaaa aatttgtaaa ccatgttatg ttattactta gtaaaagaga
     5761 tattgattta actttaagaa agtttttaaa gtctcttctt ttgagtgtac ttaaagttgc
     5821 cgttataatc attgttctgg aatattgggg aatgagtttg tccagttttg ctgctgtgat
     5881 agcatcagca ggggtagcaa taggtttggc tttacaaggt agtctatcaa attttgctgg
     5941 aggatttatt atactattga ttagaccttt taaagtagga gattacgtag aagcagcagg
     6001 ccatggagga acggttgaac aaataggact tttttataca caattggtta ctccagataa
     6061 taaacagata cttataccta atggttctgt atcaaatgat agtctaataa actattcagc
     6121 aaagaatact agacgagttg atttgacttt tagtgtaggg tatgaagatg atatactaca
     6181 tgttagaaga gtacttaaag atattgttaa taatcataaa ttaataataa atgaaccaga
     6241 accatttata ggagtagtag aacatggaga taatgctatt aaatttgcaa ctagagtttg
     6301 gtgcaagaca gaagattatt ggacaattta tcttgattta ctagaagagg ttaaagttag
     6361 gtttgacgaa gaaggaatta cgattccata tcctaaaatg gatttaacgg taaaagaatt
     6421 aaacaaaatt taatttttta atatagtgtt taaatttaag aatatcatat agatatactt
     6481 ataaggtttg taaaaaatta ataagtactg ttattttgta agtaaaaata taaaaaaatg
     6541 ggagtgtctc aaaatgaact ttttagttca tgaggcactc tttttgtacg aaataaaata
     6601 tatttttatt atttcaacaa tgaaaaagat gcttgtttct attttgagac agtataattt
     6661 ttatgtaact ttaattttag taaatataaa gttttaaaat tgataaaata ggaggaattt
     6721 ttaatataaa agggtaaata aagggtttag agggcataat atagaataaa ttaatatatt
     6781 taaggagggt ttttatgtgt aaaaaaacgt atttattagt ggtaagtatg cttatagcgg
     6841 gtttattaac tgcatgtagt gggagtccaa ctacggattc aggacaagca caagataata
     6901 caaaaaagga ggcaaatgca tcaaataacg ctttaaaaga tgaaaaaaat aatgaaaatt
     6961 taatggaaca agattttaaa gtgccataca cagatgcaat aaacatattt aaagataaat
     7021 ataaggatgc tgatatagta gatttaagtc ttgagagaga tttaaataaa tttgtttata
     7081 ctgtggaagg tgtagatgat aataatgaat ataagatgaa aattgatgct aatacaaaag
     7141 atgtattaga agataaaaca gaaaagttgg attcagaaga tttaaatgga gttgctagaa
     7201 aagaaaaatt agatttaaat gacataatta aacctcaaca agctatggaa attgcattaa
     7261 aagaacaaaa tggaatggtt aaagaatgga gtttagacaa agatttagat gttacttttt
     7321 ataaaataag aatagataaa gataaaaatg aatatgacat aaaagtagat tctaaaaagg
     7381 gaactgtatt gaaggtagaa aaagaagatt agaagattta aactatcttt aaaataattt
     7441 cttttttgaa taaattttgt ttaaaatata acaagcaggg tataaagaga ctaaataact
     7501 attttaggag gagtacggta tgtcattgaa atcactaaaa ataaaagaaa atttatattg
     7561 ggtaggttca cttgaccctg atttaagagt atttgacata attatgtata caccttatgg
     7621 gactacttat aattcatatg tattaaaagg aacagaaaaa acagttttat ttgagacagt
     7681 taaagataag cattttgaca attatattga aagattaaat gatttaaata tagattttga
     7741 aaaaatagac tatattgttg taagtcatac tgaaccagac catgcaggaa gcgttgaaaa
     7801 gcttttggat ttagctaaaa atgcaaaagt agtagcttca gaaacagcaa ttaaatatct
     7861 taaggaaatc gtaaacaaag actttgaata tgttgcagtt acagatggag atacattatc
     7921 aattggggac aaaactttag aatttttctc tgtacctatg cttcattggc cagataccat
     7981 atacacatat ataaaagagg ataaaactct tgtaacatgt gattcatttg gtagtcacta
     8041 tagtaatgat aagatagtaa atacacttga tgaaaatgaa gaaaaggatt acttggatgc
     8101 tttaagatac tattatgatt gtataatggg tccatttaaa ccatctatgg taactgctat
     8161 agaaaagata aaagatttag atatagatac tgtatgtcca ggtcatggtc cagtattaac
     8221 tgaaaatcct agaaaaatta tagaccttta ttacaactgg agtgtaaatg aacaaataaa
     8281 gttagaaaaa gaagttacaa tttgttatgt ttctgcacat ggatatacaa agattatggc
     8341 agaagctata aaagcatata ttgaaaaaaa tagcaactat aaagtaaatt tatttgatgt
     8401 aatagagcat aagcaagaag atattttggc aaaaatagca gtatcacaag gtgtattatt
     8461 tggaacacca acaatattag gagatgcgtt aaagcctata tgggatatat taatatcgtt
     8521 aaacccagtt cttcatggtg gaaaagttgc ttcagtattt ggttcatatg gatggagtgg
     8581 agaaggtata gaaaatgcta tggagagaat aagtcagctt agaatgacag cagtaaaacc
     8641 ttttgctgtt aactttaaac catcaaatga agagattgat aaattacatt cttatacagg
     8701 taaattccta gataagttaa attctacttt tggaagtaaa aagaaaacta agaaatttaa
     8761 atgtgtaatt tgtaatgaag tttttgaagg tgatagtgct cctagtgtat gccctgtatg
     8821 tggagctaag gaagaccaat ttatagaagt tgaagaagat gaagttactt ttagaaaaga
     8881 tactgatgaa tatttcgtaa tagtaggaaa tggagcagct ggtttttatg cagcagatgc
     8941 tataagaaaa agaaataaaa cttgtaagat aactatgatt tctaatgaag atgagttgac
     9001 ttactataga cctgcacttt ctgatggtat aaatgaagaa cttggttcag atttctacat
     9061 ggaagataaa gattggtatg ataaaaataa tatagtagta atattaggaa cgaatgtaga
     9121 taaattagat gaagtgaata aaactattat agtgaatgat ggagctatta aatttgataa
     9181 gcttgtaata gctacaggaa gtagaaactt tataccacca attaagggcc atgatttaga
     9241 aaatgtgttt actcttagaa atataaaaga tttatatagt gtaaaagaag cactagaaaa
     9301 atctaagaaa gttgtagtga ttggtggcgg tttattggga cttgaagctg catgggaatt
     9361 tagactaaaa ggattagaag tagtagtagt tgaagccatg gatagcatac tatcaaaaca
     9421 acttgataaa gaaggtagta aaatattaga acaatgtgta agagatacag gaatagatgt
     9481 aagattgggt gtagcagttg atggtattga aggtgatgga aaagctcaaa aagttgtatt
     9541 taaagatgga gatagtgtcg actgtgatat ggtagtattt tcaattggtg taagagcaaa
     9601 cactcaaatg gttcaggata catctgtaaa aattgataga ggtattgttg tagataagac
     9661 attacagaca aatgttaaag atatatatgc ttgtggagat gttgcacaag tgggaaatat
     9721 tagtttagca atatggccat cttcagtaga aatgggaaaa atagcagggg caaatgcaag
     9781 tggagataat ttgacatttg aaagtgaagt atatccagtt tcattagatg caatgaatgt
     9841 aaaagtattt agtattggta atatacaaaa ttttgataaa gaaatttcat caaaagatga
     9901 aggtcaaaga atatataaaa aattatttat gaaagatggt tcattagttg gagctatact
     9961 tataaatgat ttaagctgta ctgttaaatt gataagatta atatctgaaa aaggtgattt
    10021 tgaggatatt atgaaggctg atatactata atttaaatac attaaaataa aaaggagttg
    10081 tcttaaaatt gatttttttc taatcaaatt ttaaattcaa ctcctttttt gaatttttat
    10141 ataaaataac atggaaattt tagtaatgtc tgtggttaca tacataggtt taattgtttt
    10201 ttatatggat tgtctctggt ataataaatt gaattgtgtt tgactgatag atatttttat
    10261 tgaaagttaa tacctgttat gcgataataa ggacgtgtta ggggagtttt tataataaca
    10321 attaatctca gtttttgtgt tccaatagta gcatcaacac attctgatgt agtagttctt
    10381 ttcttataaa aattagttac aaatatgctt gtaattattt gatatgtaaa tttaccaata
    10441 ttataaatga tgacctcgat aataaggaga gtgaaaaata atctatgaac gaaaatattt
    10501 tgattgtgga tgatgaaaaa gaaatagcag atttaattga agtatattta aaaaatgaag
    10561 gttttacagt atacaagttt tatacaggta aggaagctct agaatgtatt gaatctaaaa
    10621 atttggatat ggctatttta gatattatgc ttcctgatat tgatggattt catatttgcc
    10681 agaaaattcg agaaaaatac tattatccta tcattatgtt aacagctaaa attgaagata
    10741 tagacaagat aatgggttta accataggtg ctgatgatta tataacaaag ccatttaacc
    10801 ctttggaagt tgttgcaaga gtaaagacac aattaagaag atatatgcga tataataatt
    10861 cttatgaaca acagtcgata attgttaatg agtatgatat taaaggattg attatcaata
    10921 aagaaacaca taaatgtagt ttatttggga aagaagtagc attaacaccg attgaatttt
    10981 ctattctttg gtatttatgt gaacatcaag gaaaagtggt tccttctgaa gaattgtttg
    11041 aagctgtatg gggagaaaaa tatcttgata ataataacac agttatggct catatagggc
    11101 gattgcgtga aaaaattcat gaaccttcta aaaacccgaa atttataaaa actgtatggg
    11161 gagtaggtta tacaattgaa aagtaaaaat attaaagtca atcctgactt tactcaagtg
    11221 agaaataaaa tttttatgag aacagcttta atggcattta tagccattat tttcatatgg
    11281 attttatatt cttttatatt gtatggtaag ttttctatct ggatagtatc attctttgaa
    11341 aatgcttttc gtatggaata taaagctgca ttgaatttat atcagcagat tttccgtaat
    11401 agcatggagc tcttcatgat actagctatg gtgattgtgt tttttataat attccgtgtt
    11461 tatttaaatt ggtttacaaa atattttagt gaaataaatc aaggtattga ctctcttatc
    11521 aaagaagatg ttggagaagt ggctttatct ccagagttat tggcaataga aaagaaaata
    11581 aactcaatta aacatatact tgaacaacgt aaatttgaga cacaaatggc agaacaacgt
    11641 aagaatgaac ttattgttta tcttgcacat gatttaaaaa caccacttac atcagttata
    11701 gggtatctga cactacttcg agatgaaagt cagatttctg aagaactgcg aaaaaaatat
    11761 ttatctattt cgttggataa ggcagagcgt cttgaagatt taattaatga attctttgaa
    11821 attacaaggt ttaatttatc aaatatatca cttgaataca gtacagtaag cttaactcgt
    11881 atgcttgaac aactaacata tgagtttaaa cctactttga tgagtaagaa tttaaaatat
    11941 acactgaatg ttacaccaaa tatgatgata aggtgtgatg ttaataaaat gcaacgtgta
    12001 tttgataact tattacgaaa tgctgtttat tatagttttg aagatactac tattgaaata
    12061 acagctgtac aggaggatga ttatataaag cttaaattta tgaatcatag caatacgatt
    12121 ccagaggaaa aacttgagcg tatttttgaa caattttaca ggttggatac atctcgtaat
    12181 tcaaacagtg gtagagctgg gttgggactt gctatagcta aagaaatagt ggagcttcat
    12241 aacgggacaa taacagctca tagcgagaac aatataatta cctttaaggt tattattccg
    12301 attgtaggaa atttgtaaga atttaagtat aaaaaaatag gaaattcttt aggataaata
    12361 aataaagagc actcttgtta ttgatataat tactgtatca aaacaagagt gcttttattt
    12421 tgatacagta attatatcaa tagaaaaatg tgaaaatata ttatgtggaa cagatgcaat
    12481 tgtaagtgaa ggttgattgg atttgaaata gaaaaagtat tttaacatgt ttctgtagat
    12541 tgtataaaaa taaataaatc aacaaaggag aatcaaagat gaataataaa aaaattgcag
    12601 ttatatttgg tggaaactca acagaatatg atgtatcatt acaatcagct tttgcagtac
    12661 ttgagaattt gaatacggaa aaatatgata ttctaccaat tggaattaca agggagggta
    12721 attggtatca ttatattgga gattataata atatccagaa taacacttgg tttgaaaggg
    12781 atactgatat aattccagtt attgtttcgc agaaccgtgt caaaaatggt attattgaat
    12841 ttttaatttc tgatgctgtt tctcagaatc atattccaaa tagtgctatt gaatcatgtg
    12901 aaaatgatat taaatacact aaacttgatt ttgtatttcc tgtattgcat ggaaaaaatg
    12961 gagaagatgg aacagtgcag gggttatttg aattggcagg tatacaggtt attggatgtg
    13021 gtactctttc ttcagcatta tgtatggaca aagacaaatc acataaactt gttcattcag
    13081 aaggtattaa agtaccaaaa tcaatattac taaaatactc agataaattt aatgtggctg
    13141 aactgtcaaa agacttaact tatccattat ttataaaacc tgtgcgtgca ggttcatcat
    13201 ttggtattag taaaatttat aaaaaagaag agttacaagt agcagtagac ttggcttttg
    13261 aacatgataa tgaagtaata attgaggaaa atattgatgg ttttgaggta gggtgtgcag
    13321 ttttaggaaa caatgactta cttgttggaa gagtagatga aatagaattg tcaaaaggat
    13381 tttttgatta tacagaaaaa tatacattga aaagttcaaa aattcatatg ccagctagaa
    13441 ttgatttgga ttgtgagaaa agaatacaag agacagcaaa aattatttat agaactcttg
    13501 gatgttctgg atttgctaga gtagatatgt ttttaactcc atctggtgaa attattttta
    13561 atgaagtcaa tacaattcct ggctttactt ctcatagtcg ttatccaaat atgatgaaag
    13621 gtattggact gtcttttgaa gaaatattgg acaagataat tgaggtgtac ataaaatgat
    13681 gaataatatt ttattagata aaaataaaga agataaaatg acaaatacta tcttattgac
    13741 taaagataaa gtttatgatg ggaatctaat tctagtaaat gcttttttac cagttaaaac
    13801 atctgaagat atagatttaa ttcctgtaga tacaaggttt ccaagtattc ttatgaaacg
    13861 tgaagctaca aacattttac aaaatatttt aaaaagtata tgtggaataa atgaaatagt
    13921 acctgtaagt ggatatcgta ctgcagagga acaacaagat atatattcaa gttctctgcg
    13981 tgacaatgga aaagacttta ctaaaaagtt tgtagcactt ccaaatcaca gtgaacatca
    14041 gacagggctt gctattgatt tagggttaaa gaaagaagtt atagatttta tctgccctga
    14101 atttccttat aatggtattt gtaatgagtt tcgtaaggca gcactacatt atggttttat
    14161 agagcgttat cagtgtaaaa aagaagaaat aacaggaata tctcaagaac catggcattt
    14221 tcgttatgtg ggatatccgc attctgagat tatcaataaa atgaatctcg ctcttgaaga
    14281 atatatagaa tatattaaga gattttcgta tacaaattgt ttaaaaatag aagataaaga
    14341 aaaaattata gaaatctttt atgtacctat tcatactaaa gaagaagtga gaatctctat
    14401 acctgaacaa tgtgtatatc aaatatcggg taacaataag gatggtttta ttgtgacatt
    14461 ttggagaaat agaaaggact aagaaatgga ggaacaagaa tgattaggaa taaatcttat
    14521 gcagggcttg attattttag gattatagct gcattactta taattgcaat tcatacatct
    14581 ccattattat catatagtaa aatggctgac tttgtgttaa ctagtataat tgctcgtatt
    14641 gctgtgccat tcttttttat gctatcaggc ttttttctaa tttcaacata taattataat
    14701 tgtaataaac tgaaatcttt tctaaaaaat gtattattta tttacgggat agctattgta
    14761 atttatattc ccttaaatat ttacactgga tatttttcca tgaataattt agtgcccaat
    14821 attattaagg acattgtatt tgatgggact ttatatcatt tatggtatct tcctgcatca
    14881 attattggtg caagtattgc atactttctt gtaaaaaaac taggtttaaa gtactcacta
    14941 gtaatcacta ttgttattta tgtaattggt atgtttggtg atagttatta tggtttttta
    15001 gaaaaaatac cactattaaa gaatttatat gggtatattt ttgaagtatc agattataca
    15061 cgaaatggta tattttttgc acctgtattt ttcatacttg gtggaataat atctaataaa
    15121 tctaattata tgtcaactaa aaatagcttg attggatttc ttatatcatt cttacttatg
    15181 ttatgtgagg gaatgttttt acataaacta ggggtacagc gtcatgatag catgtatatt
    15241 atgttattgc catgtatgta tttcttattt acagccttaa catttttgaa aggttctcga
    15301 gctaggttat tgcgaacatc atcattaatt atttatatta tacatcctat gatgattgtt
    15361 gttattcgta tgttttctaa aatattcgga atacaaactg tcttggttga caatagcctt
    15421 attcattata tagtggtaag tatagcatct tttatagctt ctataattat tatattgatt
    15481 cttaaacctc taaaaaaaga cttgaaagga gaacataagg taaataccaa tagagcttgg
    15541 attgaaattg atttaaataa tttggaacat aatgtaaaga tgatacaaaa agctatgcca
    15601 gaagattgtg aattgatggc agttgtaaaa gctaatgcct atggtcatag tgcttttgaa
    15661 gtagcgactt gtgcaaacca aataggtgta aaagcatttg cagtagcaac aatagatgag
    15721 gggattgatt tacgtcgata tggaatacta ggagaaatat tgattcttgg atatactaac
    15781 ccaataaggg caaaggaact tcataaatac aatcttacac agagtgttat tgaccttaat
    15841 catgctatct ctttaaacaa acagaaatac aacataaaat cacacattaa aattgataca
    15901 ggtatgcaca gactgggttt tgatgttaat gatgtgaggt caattttaaa ggcatttaaa
    15961 ttaaaatact tagatatatg tggcatattt acacacttgt gtgtttcaga tagtctgaaa
    16021 gatgaagatg tagactttac aaataaacaa attgaatgtt tttataagtt aattgatttt
    16081 ctgttaaaaa aaggtataaa aattcctaaa gtacatattc aaagtagtta tggttttttt
    16141 aattatccca atcttaagtg taattatgta agaattggaa ttgcattata cgggatatta
    16201 agttctccaa atgatacgac taaattgcaa cttgatttac gacctgtttt atccttaaaa
    16261 tcacaagtaa ttcttattag aaaaatacaa aaagatgata gttttggata tggaagagtc
    16321 tttattgcaa gcagagatag cgtaattgct atattatcta ttggctatgc cgatggtata
    16381 cctagaaatt tatcctgtgg aaaaagttac gtaataataa atggttgtag agcagcaata
    16441 gtgggtcgaa tttgcatgga ccaacttgct gttgatatta cagatatacc taatgtagaa
    16501 gttggtaata cggcaataat aataggaaga gataatttat ctgaattatc tgcttctgaa
    16561 gttgcaaata actcatgtag tatatcgaat gaattattga gcagagtagg aagaaggtta
    16621 aatgttataa agaagtaact caattaaata gtaatatttg ttgtactgtg taatttattt
    16681 tactctgact agacattttt agtaatatta tgtctaatat atatttttta taacttacat
    16741 gacaatttaa gttataaaaa ggtgatgttt cagattttta ttttgaaaca tcaccttttt
    16801 tgttataata tataataaaa taattatacc ttaactgtaa acttatatag attatttact
    16861 ttttaatatt agattcattt tttgagattg gtatataata aacatataga gtatataata
    16921 atagttaaag ttaaaaaagg ggaaaagcaa tatgcagtat atacaagaac tacttgattt
    16981 gactcaaaat tattgggtgt tagccacaat aatcggctta ttaagtgcat ttatagaaag
    17041 ctttatacca gccttaccac ttgttgctat agttacagca aatgctgcaa tacaaggatt
    17101 atttattgga tgtttgttat catggattgg ctcaggactt gggacaactt cattattctt
    17161 attaataagc agatttaatg atagtaagct ttttaataag ttgagaaata gtaaaactga
    17221 aaaagcaata agttggatgg ataaacaggg atttaagtta ttatttatag cgtatgcctg
    17281 tccatttatg cccggttgtt tagttactat cgcatcagct tttggtaaaa aagatttaaa
    17341 agattttgtg ccagcaatgt tggcaggaaa atttgtaatg tttatagtta taagttacgt
    17401 ggcaagtgat atagaaggtt ttataacaag tcctttaaag atagcatcat ttatattatt
    17461 ggtgtttttg tcatggaaga ttggaaatag agtaaataaa aatcttgaaa atcataatta
    17521 tgatttccat cataaaaaac atcacaatga taaagatgat aaaatgattt agcttgtacg
    17581 aaataaaacg tatcttaaaa tgatttagta ctaaattatt ttaagatacg ttttattttt
    17641 tgtattaagg tacaaaattt ttagttcttt tgtaaactaa aatatataaa acttatttat
    17701 acttagttca aaatattgtt atttattttt tctacaacta taataaaata taaaattgat
    17761 atccaatcaa aaaaataact atgaaattta atagcttaga tatgaatttt tctgtttttg
    17821 agttagtttt tataggtagt aaagaaatgt ttatggtaat gggataaaac aattcaatac
    17881 cttctttagt aataaggtca agacacaagt gagatagata tcctattata aacccactgg
    17941 acaaacatga gaaaactata ttattgttag tgaagattgt cagagattta aaaaaactat
    18001 aaataagtaa taaggcaatt agactgtgag taaaccctct atgtctaaac ctacttccaa
    18061 ataatttgta tattaacata aattttttac ttatgtaaga acctctcata tctatatctg
    18121 gaaataaaga acctaaatat gcaaaataaa tataaattat aattaatact attttatatg
    18181 caatatcgta tttaactagg tatagattgt ttataaaggg gagtatcaaa agtgcgaata
    18241 tataacctcc cctttcatgt gtttctttta tcatataaaa atcctcctga atcgtcacta
    18301 taaacattat attggtaaat ttagactatc ttttattata ttatatagca aacataagtt
    18361 tttttcaaaa ggattttaat atttaattaa tcttgagatt ttaaattttt gtaattttct
    18421 aaagcaccat tccaatttac tacattaaac cagttgtcaa tgtattcatt tcttctattt
    18481 tgatatttta aatagtaagc atgctcccaa acatcaagtc ctattatagg agttaggttt
    18541 ttacttacag ggctatcctg atttggagta gtcataatag ataatttccc atctttagta
    18601 gctacaagcc aagcccaacc agaaccaaag acatctaaag cagatttttg gaactcttgc
    18661 ttaaattttt caaaagaacc aaagtctcta tcaatagctt cttttaaaga ttcagaaggt
    18721 atggtttttt ctggcgtcat tatatcaaaa aagaatttat gattataagc tccacctgca
    18781 ttatttctta cagttgtagc aatatcttta ggtaaagaat ctaaattttg caataattca
    18841 cataaagaat aattataaag ctcaggatat ttttcaagag cagcatttaa tttatcaaca
    18901 taagcttgat aatgcttatc atgatgcagt ttcattgttt ctttatctat ataaggttca
    18961 agtgcatcat atgcataagg taatggttta accttaaatt tgttattttc aggtgtaaaa
    19021 gcaaatgaag ttatgcactg tgagattata aataaagaca taataactgg tattaatatt
    19081 tttttcttca taaaaatcac ctcctaatat agtatttcta gaaataaaaa aaatatgaaa
    19141 tattaacaga taatttataa gaatttaata gcaatttcat tttaaattga ataagtttta
    19201 aagccaaaga caaaactatg aaatatagaa taagactaaa ggacagaaag gaattttgat
    19261 tatatggacg gcaatatttc aatttattat aaaggtgata tatctaaaaa agaagatatt
    19321 aaatttaaaa taaaagaatc tgtaaataat acaagacttt ctagtagaat agagtataag
    19381 gatgaggaaa aaacttttga ttttgaaaga tttaatgtaa ttgatgctat ttatggaaat
    19441 aaaccatttg aaaaagatgg aaaagttatt gtttttaatg gaaatatata taactatcat
    19501 gaaataaaag aagaattaat taaaaaagga cacaatttta ctacaaatga tgatattgaa
    19561 gtcttattgg catcttatat agaatttggt aagaattgtg tacataagat taaaggaatg
    19621 ttcaacttta taatctatga tagagaaaat gaaagtatat ttggagcaag agatttattt
    19681 gggataaaac cactttatta tataaataag gaaaatgcaa taattttttc ctcagagtat
    19741 aagtttttac ttgaatatat gaaaaattta aatataaatg aaagaagctt acaaagttat
    19801 ttttcatttc aatatgtact tcctgaagat actatgatac aaggaataag gctgatacca
    19861 gcaggtcact attttagggt agaaaatggt atactatctt taaagagata taataaactt
    19921 gagtttagaa gtagtacaaa atttttttat actaaaaatc acttaggcaa tagagatgtg
    19981 aacgaggatg atataagaaa tatagtagta gattcaatag taactcatat ggaagaggag
    20041 aaagaaattg gaacatttct gtctggtgga atagattcat ctattataac tactgtggct
    20101 tcacaaatta atccaaatat aaaatctttt tctgcaggct ttagtgtcaa aggatatagt
    20161 gaattagagg tagcaaagaa aacagctgat aagttaggta tagaaaatat ccagattaat
    20221 ataacacaag atgaatatat aaaatcatta ccgaatgtaa tttattcttt ggatgaccct
    20281 atagcagacc cttcagaagt aggtctttat ttcttaatta aagaggcagg taaacatgtt
    20341 aaagtagcat tgtctggaga aggagcagat gaattatttg gaggatataa tatatataaa
    20401 gagtatagta ctatgaaatc agttgtcaat tcacctactt atattaaaag tatattagga
    20461 agagtttcag aacttatgcc aaacataaaa ggaagaaatt atctttatag agctacaaca
    20521 ccattagaaa aaagatatat aggaaatgca aaagtttttg aaaacagcga agtaaaaaga
    20581 ttctttttta agtataagga aaagaatata tatgaatacc tgttgtctaa tttgtataga
    20641 gatgcacaaa aaaataatta cgattatata agtaaaatgc aacatataga tgtgaataca
    20701 tggcttcaag gcgatatact tcaaaaaatt agcaaacttt ctacagctga gcaggttgaa
    20761 cttagagtac catttttata taaagatgta tttgatgtag caaaaaattt aagaatggag
    20821 caaaaaataa ataagaataa tacaaaagtt ttacttagag aggcgtttag agaaatagtc
    20881 ccagaacatg ttgttcaaag gaaaaaatta ggatttccaa ctccaataag agtttggtta
    20941 aaagattctc taggggatat tgtaaaggaa actatttata attcaaatgt agatgaattt
    21001 atagataaaa aatatgcaat aaaactttta gatacgcatc ttaaaggtca tagagataat
    21061 tcgagaaaaa tatggactat atttacattt tgtctatggc atcaattatt tattgagcat
    21121 aaaaatgtcg agtattaata ctgttttcaa tattaatcag agggcaaaaa catgcaatgt
    21181 tttcaccctc ttgattatta tggaatagga taagtagaat tttgattgat tagtttacta
    21241 tctcaataaa attattggca aatattttga caagactact ttcaacagct aaatttaagt
    21301 tttgtccatc atcatatcca gcggaaatca atcctagtaa gtttccaaac atatctaaaa
    21361 gagctcctcc tgaactacca ctagagattg gagctgtaaa ttgtatcatt tgaaccgttt
    21421 caaaatcacg aaaagctgaa ataattccat ctgaaactgt attaaaaaga cctaaagggc
    21481 ttccaattgc aactattttt tgacctctca caggtttttt actgacttta acaggtattg
    21541 gcttgcattt tctatcaacc tttatcacag ctaaatcata atctgaatgg tattttataa
    21601 tttggtaaga tgtataaact ttatcatcat tttcaaatct aactaaaaat gaatacccat
    21661 cattgactac atgaagattc gtaagtatat aaccttcatt atttattact actccagaac
    21721 cgctcttaaa cggtttattt tcgttattgc acacaacaat cataacaaca gaagctgata
    21781 actttgcaag gtcttcataa gaaagttcta cttcctcatc ttgtacaatt tttttagatg
    21841 ttagatttgt gttattaagt gtatttttag agttaggttt attcgtagta ggagaagtct
    21901 tattggtatt ttcactgtaa tttatatttg taatatgcct ttcaaaaggt atttctaata
    21961 tatttggagt cttcctagaa agttcaaata gagtagaaaa ttttgaacat tcaggatata
    22021 aatcaagaat atctttattt ggatttatat ataaaatatc acacccaagt tgtgataaaa
    22081 aatataagaa aaaaagttct tgccttttaa tatttccaaa gtatactatc tttggtgaaa
    22141 tagtagtctt caccttgtta taaaataatt taggtagaaa atagtccatc caacacaaaa
    22201 gtttaactgc aaagtttttg atgatagagg atgtacaatt tggcatactt gtggaaaata
    22261 aatctaaagt atttttaaat gcaatctttt tagtccaatt taaggtgtca ttttctattt
    22321 tacatggaaa gtcgatatta tataaatccc aactgttaaa cttagaacta ttataaatat
    22381 taaaaatttt aagcatctta tctgtttgtt ctttgtcaaa atttattttt agattgttta
    22441 atctaatata gggaattgta ggattattaa aaaaataagt atctatattt ttaatttttt
    22501 ctatgtattt atcaattgaa tcatcaacac ctatatatct tgtaaagtag acttctttaa
    22561 tatatgaaga acgcttattt ttataggtag tatcagatat aaattcaatt agaggttcag
    22621 ttgacttttt tattgaaatc tttaatggtt taatagtaca aatcatattt tttctcctat
    22681 aataagatga tataatctat tataaaacaa cttaaaacaa tatagtacaa taattttgta
    22741 gtttcaaaat aaaatatgta cttgtttata taaatgatat ataattacat attaaacata
    22801 gcttttatac atttaataaa gtatgtaaaa tctatgtaaa aagtaagaaa tataaacatt
    22861 tttttaatta tattttaaaa atatcaagca agttttcttc acaaatgaat aaaaaatgtt
    22921 ataatatgat taaagaaaaa gataaataat tagcaagatt tgtttagcta aaattaacaa
    22981 gggagcgata aattatgggt ataacattat caaaaggcca aaaggttgat ttaactaaag
    23041 gaaatccagg tcttaaaaat attttagtag gtttaggatg ggatactaac aagtatgatg
    23101 gtggatttga ctttgattta gatacagcag catttttaac aggagcaagt ggaagtgtta
    23161 ctaatgatgg agattttgta ttttacaaca atttaaaaca tacatctgga gcagttgagc
    23221 atctaggaga taacagaact ggcgaaggtg atggagatga tgaacaaata gttgttgatt
    23281 tatctaagat tcctggagaa ataagcaaga tttcttttac tgttacaatt catgatgcga
    23341 cagaaagaag acaaaatttt ggacaagtaa gtaattctta tataagaata gtagataaag
    23401 acacaaatga agagttaata aagtatgaat taggagaaga ttttagtata gaaacagcta
    23461 tagtagtagc tgaaatatat aagcacaatg gagaatggaa gtttaatgca ctaggttctg
    23521 gctttgaagg tggtcttgct gcattatgtg gaaactttgg aataaactta taatttcaac
    23581 tataacaata aactaaaggg ggatattttc catggctata gtattaaaaa aaggacaaaa
    23641 aatcgattta actaagggaa atccaggtct taaaaatata aaacttggac taggatggga
    23701 tacaaattca tttgatagtg gctatgatta tgatttagat gtaagtgttt tcatggttgg
    23761 agaatctcaa agagttgaaa aagatgaaga ttttatattc tacaataact taaaacatcc
    23821 atctggagca gttgaacact taggtgataa tagaactggt gaaggtgatg gagatgatga
    23881 ggaaatatta gtgaatttag agacaatgcc aaagcatata caaaagatag ctgtaacagt
    23941 tacaatatat gaggctgctg aaagaagaca aaattttgga caagtaagta actcatatat
    24001 aagagtatta aattctgaaa atgatgaaga aatattaaga tatgacttag gtgaagaatt
    24061 tagtatagaa actgcaatta cagtatgtga gatatataag tataatggag aatggaagtt
    24121 tagtgcagtt ggagcaggat ttgaaggtgg cttagaggca ctttgtagaa actatggctt
    24181 aaatgtttaa tttaagcaat ataatatatt aaatataaat aacctataca aataatgtat
    24241 aggttatatt atataaaatt ttgtggaggt ttagtatgtc gattaattta tcaaaaggtg
    24301 ataaaataga tttaaaaaaa tctaacccag gactgagtaa catacttgta ggtctaggat
    24361 gggaccctgt gcaacaatct ggaggaggtt tttttaaatc gttatttggt ggaggacaag
    24421 ctgatataga ttgtgatgca tctgtattta tgcttaatca agaaggtaaa ttaagtggaa
    24481 taaaagattt aatttatttt ggaaatctaa aaagtgcctg taaatcagtt ttgcatacag
    24541 gagacaatct aactggtgag ggtacaggtg atgatgaaca aatcctagtt aatttggata
    24601 aagttccatc aaatattcat aaattattgt ttgtggtaaa tatatacaat tgtgtagata
    24661 gaaaacaaca ctttggaatg atagaaaatg cctatataag agttgaagac caaggtaata
    24721 agaaagagat agcaaaatac aatctatctg ataattattc tgaaaaaact actcttatag
    24781 taggagctat atatagaaaa gatggaagtt ggcaatttaa agcaattggt gaaggaacaa
    24841 aagatgcggg tcttaaagaa gtaatgcaaa atttagacag gattgagtgt gcatatggaa
    24901 tttaataatg atatcaaata ttataatgta gataaagaag aagttacaaa agacttatct
    24961 gttaatcctg aaaaaggttt atcagaatca gaagtcaaga ctagaagaga aaaatatggt
    25021 ttgaatgaat ttactccaaa agaagagggt agtttttggg atgatttaaa ggaaagttta
    25081 agtgaaccaa tgatagttat cttgattatt gcagcagtag taagtgcagt aattggggaa
    25141 actcatgatg caatagggat tgtaggtgct atagcaatag gtatagcaat aggtatgatt
    25201 acagaaggtc gttctaagaa agcagcagaa gctctttcta agttgactga aaacatagaa
    25261 gtaaaagtat tgagagatgg ggaagtacat caaatttcta agagtgaatt ggtaccaggt
    25321 gatatagtat atattgaaac tggtgacatg gtacctgctg atggtagact tatagaaagt
    25381 ataaacctta aaattagaga agatatgtta acaggagaat ctgatgacgt atctaaaaag
    25441 tgtgatgtag tagtttctat ggaagagata gaatctaaag gagcagtagt agtacaggaa
    25501 ccaatacctg caaaacagat aaatatggtg tttggtggta cacttgtagc ttatggtaga
    25561 ggagctctag ttgtaacttc aattggagat aatagtgaaa tgggtaaaat tgctcaaaac
    25621 ttatcagaaa cagatgagca aactccactt cagataaaac ttggaaattt aggtggtttg
    25681 atagccaaag tttctagtgc agtagcagga ttactattta tatttatggt tttccaaatg
    25741 ataagtaaga atgtattaaa tgtagatatg tctggaatat taccgttttt agaatcaata
    25801 gacccagtta aaacagcatt tacagtatgt gttgcgttga tagttgcagc agtgccagaa
    25861 ggtcttccaa ctatgataaa tatgacactt gcaataacaa tgcaaaaaat ggctaaaata
    25921 aatgcattgg ttactaaaaa agaagcttgt gaaacgatag gttctgtttc tgtaatatgt
    25981 tcagataaaa ctggtacatt aactgaaaat agaatgactg tagaagttgc atatgttgat
    26041 ggtagatata ttgaaagttc agaagaggaa ataaatagtt attttgaaga aaactgtatg
    26101 ataaactcta cagctgatgt agagcacaat gatggtgata ttaagtattt aggaagtgct
    26161 actgaatgtg cattgctttt atattacaaa aacgtagatt atagacaagt tagaaaaaat
    26221 tctaatatag tagctcaaaa tccttttact tcagattcaa agagaatgac ttctgttata
    26281 ggtcaagata atcatcatgt actattatca aaaggagcac cagaagtctt acttgaatta
    26341 tgttcacata ttcaaagagg aaaagacata gttccattaa ctgaaaatat aaaacatgag
    26401 attttagaag aaataaagaa attgcaaata aaatcaatga gaactttagg gtttgcatat
    26461 aaagaaatct cacaagctga agaagaagca gcagtaactg ctgaaagtga tgctatgaat
    26521 gtaagtgcaa tggaaaataa tttagtattt agtggttttg ttggtataag agacccactt
    26581 agaaaagatg ttatagagtc tgtaaataca gcaaataaag ctggtgtttc tgtaaaaatg
    26641 cttacaggag ataatataaa tacggcaaga gctataggtg aagagttagg cctattaaaa
    26701 aataatatga gagtggttga agcttcatat atagatactt tagatgatga agaattaaaa
    26761 caagagatac aaagtatttc aatcgtggca agaagtaaac cagatagtaa aatgagaata
    26821 gtttcagctc tgcaaaagag cggagatgtt gttgcagtaa caggtgatgg tataaatgat
    26881 gctccagcac tttcaaaagc agatgttggt atagcaatgg gtatatctgg tacagaggta
    26941 tctaaaaacg cagcagacat aattttaact gatgatagtt ttagtaccat tgtaaaaggt
    27001 attaaatggg gtagaggaat ttatgataac ttccaaagat tcgttcaatt ccaattaact
    27061 gtaaatgtaa ttgcattttt agtggctata atatctcaag ttatgggaca agagatgcca
    27121 tttactacaa tacaattatt atgggtaaac atcattatgg atggaccacc agcactagca
    27181 ttaggtttag agccagttag ggaccatgtg ttaaacagaa aacctgttga tagaaaagcc
    27241 aatataattt ctaagtcaat ggtgtataca atagtattaa atgcatttta tataacagca
    27301 atactaatgt tacaatctac atttaatttc ttaggagttg atgaagcgca taagggaaca
    27361 gtaatgtttg cgttatttgc ttttagtgca ctgtttaatg catttaactg tagagagttt
    27421 aatgcagata gtatcttccc taattttaca cataacaaat tagcactaca aataatagtg
    27481 ttgacaggaa ttgcacaagt aatatttact cagctattcc aagatttctt taactctgta
    27541 gcaatggatt ttatgacatg ggtaaaagtt ttatgtgtag cagcaagtgt aattgtggtt
    27601 aatgaagttg taaaatgtat aataagactg gtaaaaccaa aaaagactgc ttaaaacaaa
    27661 ttttttagaa gaaaacagac tgactcaaaa tatgaatttt gggtcagttc tgaataaaca
    27721 tttaaattgg gaggatagtt atgggtgact caaaggtatt tgaaaaaata ttctccagcc
    27781 aatcagatag aggaaattac actccttcaa agggatatct aagttatttt atttcgtata
    27841 ttggtttaga agatgaagtt ttgtacaatc tcgagatatt taagacaaaa caaaatattg
    27901 atagcaaaaa agatattgct ttatttactg atgttatagc aaatcctagt gattttgata
    27961 ttataaatta ttttaaaagt ggacttcaaa aatatagaac tagcatggaa gatgtagata
    28021 taaatatttt gggatttgaa gatattgatt ataaaataaa gcaagcaatg gatagagtgt
    28081 taaaagaaga ggaaaaagaa tttactaatg atagagttaa acaaaatttt atagtgaaaa
    28141 taatggcatg gataaaaatt tatatcggtg ctttagatat aaataaaaat gaagctccaa
    28201 aagtaatatt ttatggagat ataaaaaaac atgaagttta tttactctta atattatact
    28261 tggcaggttt tgatgtttta tatcttaatc caaattcaaa gagtaatata gatattttaa
    28321 aatcagaaag atacaatata gagtttgaag aagccaacat aatagaagaa aaaatttctt
    28381 ttgaagaaag ggttatttta ggggaaaaaa tagataaaag ttctgtaaaa aaagctttta
    28441 ctgttggggc agaagcatca aagcgtataa gtgaggaatt gttaaatgat gcaggattta
    28501 taaaaccttg gcaactccaa gatagaaaaa taaaaaatct acttctaagt tcaactgttg
    28561 atgaaatatc aatatactgg aatcaaccac ttaaattaag accaggattt aagtttaatg
    28621 atgctattgt agaagctcca aattttcttt ctaagattaa tggaatatat aacgataaga
    28681 atgaatatat taagttttta gatttattaa gagattcgga aagttcaaca tttattgaat
    28741 ttaatggaga tgtagataga ttttcaaaag cttttacaag agaagctttt agtttatcct
    28801 ttttattgga ttcaaaaggt gcaatagata aaaactctgt tttaaataat aaagattatt
    28861 ccatatcaac actagcattg aatcaacaaa ttatgatttt agagaaagtg gaagagttgt
    28921 tagaaggaag tatgtttttg aatggtttaa gtggagaaga caagataaaa ggtctattta
    28981 cagtacttca catggataag aaatttgttc atatgatgaa caatttcgat tactcactta
    29041 taaacccaaa attgattata tacatgtaca agagtattgt atttgataaa gaaatagttt
    29101 ttcttatgct tttacttagt aagattggat ttgatattat catattatgt ccaggaggag
    29161 aaaacaatat agagaatgtt ataaataacc aattgattga tgtacacaga ttggataaaa
    29221 tggtatatga ccttaaatta aattcgcttg aaaatgatat acctttactt aaaaaaattt
    29281 ttggaaagag gagacgattt tagatgggga taaatataaa tagtttttca aaagataaga
    29341 actctgtaga ggttactgag aatttgccta cagcagttca agaagaaaac ttcgatataa
    29401 tggaatatac aaataataaa aaaaatgaac tgagaaagtc taaggaagtt gaggcattga
    29461 catctcttat agaagtagaa aatccagata cgattttaca gtttggtagg aaagcatctg
    29521 aaggagtagc aagagtttct gatagccttt taaatacaat aaaattaaat agaaatgaag
    29581 aaaattctaa aatgctggtt catttaacta aaataatgga caagtttgat ttagacgatt
    29641 ttcaagaaac taaggaacca aatttcgttc aaaaactttt caaaaaagct aataatgcca
    29701 ttgaaatgat gtttcaaaag tatgaaacat tgggaggaga agttgagaaa attcaaattg
    29761 agcttgaaca atacgaaaga gatatagcac tttctaataa gcaaataggt gctatgttaa
    29821 atgaaaactt tgagttttac aatgaacttc aaaaatatat tgttgctgga gaaatggcaa
    29881 tagaagaaat ggataatgaa atactacctt tctttaaaca aaaatcagag actagtggag
    29941 accaaatgga tgttgtcaat tatcaagaac tattaaaagt ttatgatatg ttaaatcaaa
    30001 gagtatatga tttaaggata gcagaaaata tagctatcca aacaatacct atgcttagag
    30061 gtatgcaaca taataattat ggtttaatta gaaaaataaa tagtgcattt gtcgtaactt
    30121 taccagtatt taaacaatgt ttatctcaag ctatattact taaaaagcaa gaattacaag
    30181 caaaatctct aaaagcactt gatgacaaaa ctaatgaatt attgcttaga aatgcacaaa
    30241 atgtaagtac tcaaagtgca caaatagcta gaatggctgg aacaagttct gttcaaatag
    30301 aaacattgga aaaaatgtac aatactatca aatctggtat agatgaaact atgagaatag
    30361 aagaaaacaa tagagcttta attaaggata atacaaagag attggaagaa ttaaatacga
    30421 ctataattta taataagtag tattatatta agggctaatt tgtataaagt tggccctttc
    30481 tatgtatatg aggaggctag acattgaaat atttcgatta tatctgcaaa gatgatttgg
    30541 agagaatttt tttgaaggag ccagaagatt ttagtgctaa gactgaaaaa gatgtgttga
    30601 aatatgcact gggcgctttt ttatacgttc cagctactca atataatatg atttataaga
    30661 gtattatagg ggatgttaag ggagttagac cattagctat ttgtttagaa gatgctgttg
    30721 gagtaaatgg agagttggag gccatagaaa atcttagatt aattttaaaa aatattagca
    30781 atgaaagtat aactaataaa gatggaatac cactaatttt tgtaagaata aaagatgtgg
    30841 agcaactgtt gagaattaaa gagattataa ttaaaaatag tcattttata acaggaatat
    30901 taattcctaa agcaaattcg gagttaattg aaaattgtat agaagcttta gattctatga
    30961 atcttcaaga tatgtatgtt attccgatag tagagacaaa agaatttata tataatgaaa
    31021 aaaaagaact tagttttact aatttgtaca atgctatttt aagacataag tcaagaatat
    31081 taagcattag agtaggcata actgatatat tagggatgta tggtataagg agagataaaa
    31141 acttttctat atataataat ttgatttgtt cttcatttat attagatata atcacatatc
    31201 ttcaaagacc agagttagat atacctataa gtggtggagt atcagaattt tttgatatga
    31261 cgaataaaga tataagaaat aagtatatag aagaaatatt attggataaa tatcatggat
    31321 taattggaaa gaccgtaatt catccaatgc aaattcaaat tgtacaagcg ctatctacag
    31381 tatcatatga agattttact gatgctttgg atatactgga tagtacagac agtaagtatg
    31441 gtgtgagcaa gggtgtatta ggagagagaa tgaatgaaac aaatccacat tttttatggg
    31501 ctaaaaaaac attgattcta tctaaaatat atggtgtatt aaataaagga gtagactatg
    31561 aagaattgct taaattttaa ttgtgagatt gacattattg ataatccatt gaatttagaa
    31621 ctaaatgatt ttttagacgt aggaataaga aataatagca aaagacgttt tttgtttatc
    31681 tcaaagaaac tcggtaaaca tttagcatgt aagccaagtg agatggataa tttgggaaaa
    31741 ttaatggcta caatttataa tgaaaaaaat aaggaagaat caaatggtac tgttatagct
    31801 tttgctgaaa ctggtacagc tgttgggcat agtttttttg attacttatg tggagattat
    31861 gaatttattc atactactag agagcagttt gacgagttag aaaatctgga atttttagag
    31921 gaacattccc atgcaacaga ccagaattta tactttggta tgcttaacaa ctttaaattt
    31981 ggagatgaga taatattggt tgatgatgag attaccacag ccaatacatg catgaatata
    32041 attaggaaaa ttcaaagcat ttatcctaaa aagaaataca ctatatgctc aatactcaat
    32101 tgggtaagtg atgaaaattt aagtaaagtt actcgtttag aaagagagct agattgtaag
    32161 atagattttg tatacttatt taaaggaaac tttaaatttt atatagatga agatattatt
    32221 tcaaattaca acgataatta tagtattact aaattagaga ctatttcaag tgataaagta
    32281 aatttagtag taaatcatat ttatgttgat ttagaagatt atattggaaa taagaaatat
    32341 gtaaaatata caggaagatt tggaattaat agaagagaac aatttagatt aaaagaaatc
    32401 gttaagagag aaagtaaaaa aataactatg gccagtaaag aatctttaaa aaatgaaaaa
    32461 gaaaagattc tatttttagg tactgaagaa tttatgtata tacctatgct gtttgcaaaa
    32521 gaaaaagaaa atcaatatga tatatactat cattcaacaa caagaagtcc aattattaat
    32581 attgataaga ataattatcc tattaaaagt aaatttatgc taaagagttt ttataatata
    32641 gatattcaaa attatattta caatatagat aaacataatt tttctaagtg ttatttattt
    32701 gtagagctga ataaaagtga aaattcttat ctagaattta ttgatataat taaaaaaaca
    32761 agtataaaag aattaactat agtatgttgt agctaaagtg ttttaacagg ataaaatata
    32821 tcacgatttt aagataggag ttgagtcata tgagagattt tagcacgtat tctaaagatg
    32881 atgttatttt tttattaaaa gatatatcaa atttaattga agaagaagga aataaagaaa
    32941 gagaattaaa aatacaaaat ggtagacatt attcagaaat gataccaata gagtatgaag
    33001 ttagtgaaga ttatctgaat ttatatcatg agaaactaag agaaaataaa gataaacttg
    33061 cattttctat aggagttatg tgtgaaaaaa taattaaaaa aaatggaaat gatgtagtac
    33121 tagtttcact tgctagagca ggaacaccta ttggtatttt ggcaaaaaga tatataagaa
    33181 gcaagtataa tataagttta cctcactata caatctctat aataagagat aagggaatag
    33241 atatgaatgc aattgaatat atagtaaaga atcatccaag ttcaaaaatt cagtttttag
    33301 atggatggac tggtaaggga actatatcaa aagaacttga aaaagcatgt gatgaactta
    33361 atgttaaatt taaaaaacat tttgactcaa cacttgctgt attagctgac cctgctggat
    33421 attcaggcct ttatggaatt agagaagatt tcttaatacc aagtgcatgt ttaaattcaa
    33481 ccgtttctgg tttagtaagt agaactgtac taagagagga tttaattggt aaaaatgact
    33541 ttcatggagc taagttttat agacatttaa aagataaaga tgaatctatg aactatatcg
    33601 aaactataga agaatgtttt aaaaatcaat ttaagaatat atctgatgaa gttgaaaact
    33661 gggaaagtga cattataaca agagatggat actttgatgt tttaaatata aaagaaaagt
    33721 ataacataac agatattaac tttatcaaac caggtgtagg ggaaacgaca agggttttac
    33781 ttagaagagt tccgtataag attcttgtta aagacttaaa tgataaatct ttagaccata
    33841 tattcatatt agctaaggag aaaaatgttg aagttgaaca aatggattta aaagcctata
    33901 aatgttgtgg aataataaaa aatatgaaag atatttagga aatatattag acaggagaat
    33961 attgaatgat tgttttttca gatttagaca ggagtatcat ttactccaat aaatttttaa
    34021 atgctgatag taaatatact aatatagaaa tttataggga aaaagaaata tcttatatat
    34081 ctttagatac tataaattta ataaagcaaa tacaatatta tggtatgttt atacctacaa
    34141 ctactagaac agtggagcaa tttaagcgta tagaatttaa taaatatggg atttattttc
    34201 cttggagtat aacttcaaat ggaggagtta tacttaaaga taatgaaata ttgaaatcat
    34261 ggagtgaaaa aatagataaa ctaaaatgtg attatgagcc cattgaaagt atgattcata
    34321 aatttaaaga ctatttgaat gtagatggaa taactaattt taaagttgca gaagatacat
    34381 ttttttatat agttgttgat ttatcaagat ttaatttgga ttcaatcaaa gaatatacaa
    34441 atatattgga atcaaaaaat tggaagtttt atgtgagtgg cagaaaaata tattttatac
    34501 caaaagaaat ttcaaaagaa aatgctataa aatacttgac taaagaatta ggaatagaat
    34561 atttttatgc agttggagat tctattatgg actatggtat gcttaatatc tcaaataaat
    34621 cctatgtatt gaagcatggt gatataaata aaaatgaaat agaaaattca tttatatcaa
    34681 gttctttcaa tggaatgagt ggaactgaag agatactatc taacatttta gacgagaact
    34741 gcctacttaa catataatga ctgatatata aataataaac tagaaaaatc tgaaataaat
    34801 tatagtaaag tttatcatac taatttattt cagattttta tcaatttata tttaagtaag
    34861 aactcaatat gttaaaatga aggtggagtc attgcccaga ctgagataca tacctcatca
    34921 tcataatttt catacacatg tggtatagta ctgttaaaat aaaaactatc tccttcctcc
    34981 aatagatatt ccttatttcc aagtgttatc ttcattttac cttttattat ataaccacat
    35041 tcttctcctt cgtgtgtcac aaattcactg tttttttgtg tatgaccatc tagcgtaaca
    35101 agtataaatt ctattttttt cccagataaa ttaggaacaa gaagttcata aaattttgta
    35161 gaatcattag ttactatttt ttttcgatta tttttcttta ctactatatc agagtcttct
    35221 cttccaatct cttcaaaaaa ataacctata tttatatcaa gagcttttga tattttccac
    35281 attgctacaa tagatggaac aaccatatta cgctcaattt gacttattaa gcctgtactt
    35341 aaatctgaat tttttgctaa agtagagata cttatatttt tagattttct aagagatcta
    35401 attttgcttc caacatctat attcattaga tacaaacccc ctcagacatg attataacat
    35461 ataatttata aagattaata aaataaaaaa aaagttttac aatacaagta ttttttatgt
    35521 tatattgaat tttctgaaaa gatgcattat aatagtatta atattcaata tattgaatat
    35581 tgataacgat attttaattt aatgaaatgg aggtagttaa gatgaagagt tttgtaagcc
    35641 ctgataacat ttgggtatta tgggcaattg taactggatg ggcagcattt agtatttact
    35701 tggaacaaaa gtacaattgg gcatcaaaag tgtctggagc aataatagct cttgtaggag
    35761 caatgttatt atcaaatcta aatattatac cagtagagtc tgttgtatat gaccaagtat
    35821 ggggatatgt tgttccttta gccatagctt tattgttata tcaatgtaat attaaaaaga
    35881 tatggaaaga aagtggaaga ttgctcatta tatttcttgt aggttctgta ggaactgtac
    35941 ttggagctat gattggattt ttagcattaa aaaatgtagt accagattta aatattgttg
    36001 cagctatgat gacaggttct tatataggtg gaaatgtaaa ctttgctgct atgtcagggg
    36061 cgtttgatgc gccaggagaa ttagtatcag caacagttgt agcagataat cttttaatgg
    36121 cattatattt ctttgtctta atagctatac catcaattgg attttttaga aaacatttta
    36181 aacatccaca tgtagatgaa atggaaagta taggtataac tgaaggagaa acagtagcag
    36241 caaattattg gggaagaaaa gaaatatctt taaaagatat agcaatagcc attggtagcg
    36301 cttttataat tgttgcagta tctgtagaac tatcaacttg gtttaaagct ataataccat
    36361 tatcaaatcc ttttttagca atgttaaata ctttatttgg aaatcaatat ctaataataa
    36421 ctactttgac tatgttgttt gccacattta tgcctaattt ctttggtgat ataaaaggag
    36481 cacaggaatt gggtacattt ttaatataca tattctttgt tgtagtgggt gttcctgctt
    36541 caataacatt aataattcaa aaatcaccat tactactttt atactgcgga ataatggtac
    36601 taataaacat gctagttacg tttatagttg caaaaatatt taagtttagc ttagaagaag
    36661 ctattcttgc atctaatgca aatattggtg gacctacaac agcagcagct atggcaatat
    36721 caaaaggatg gtctaagcta gtaggaccaa tacttatagt tggtacattt ggatacatag
    36781 ttggtaatta ttttggtctt ttagtaggaa atattttaat ataattttac gtgaaaaaaa
    36841 gttgtttttt agaaggattt tatttaattg gaggttgtta tgattttcga tggacattca
    36901 gatacttggg cagatgtaac aataagaagg cttaacgggg aaaaagatgt atttagaaga
    36961 atccatcttg ataattttaa aagagcaaat atagaaggag ctatttttgt aatatggata
    37021 gacccaccat atgataaaga gcctgaaaaa agagttaaac aaattataag ctctataaaa
    37081 gatgaaattg aagatatgaa agatgttgta aacatagtaa aaaaatattc agatatagat
    37141 aaaggtataa gtgaaaacaa aataaatatt ttaattggtc ttgaaggatt aagccatatt
    37201 ggaagaaata tagatttatt agattatttt tataaagaag ttggtgcaag acatgcatca
    37261 ttaacttgga atgaacagaa tgaacttgct acaggatgtt taggggatga aaatcgtggt
    37321 ttaactgaaa taggtaaaaa agcagtcaat aaaatggaaa aattgggcat gatagtagat
    37381 gtgtcacatt taaatgaaaa atcattttgg gatttaatgt ctgttgcaag taagccagtt
    37441 atagcttctc attctaatgc taggagttta tgtgatgcta aaagaaatct tacagataat
    37501 caattaaaag aaatttcaaa tacaggtgga ttagttggaa taaatagttt tagaggattt
    37561 actaatagta atcctaagaa gcaagattta atacatttgg ttgaccatat agactatatg
    37621 gtaaatctta taggtataga acatgtatct tttggttttg attttagtga ttacttaggg
    37681 aaagagacta taggttcttt tactggaaat gctagtgtgc caagtgtaga tggtcttgaa
    37741 agcacacata cagcacagaa catagtagta gagcttgaaa atagaggtta taaaaagaaa
    37801 gatatagagt taatctctag tggtaatttt tataggctct ttaaagatat actaaaataa
    37861 tataataaag aacttaaatt tataaaatag tatatttata caaataatat ctacatattt
    37921 aaattggcgt tcataattta ttaaattaaa ttttaatgtt actagaagtt tcaattctag
    37981 taacattttt tatgttaaaa acagatatag atatgtattg acaatgataa ttattattga
    38041 taaactatta aagtgaaaat gataataatt ttcagtttaa ttaataaaag atttttaagg
    38101 agggagaatg aagaaaaggt atttagtcat aggaataata attttgtctt atttttcttt
    38161 atttatagga gctgaagata taaatataat gcatatattt gccaaaaatc agcataaact
    38221 tatgatattt atcatgagta gaataccaag attaataagt atattgattg ctggtgtagg
    38281 aatgagcata gcaggtctta taatgcaaca gataagtaag aataaatttg tatcacctac
    38341 aacaggtgct acaatagatg cagcacaatt tgggatagta atatgtatgc ttttagtacc
    38401 aactgcctct atttttacaa agacaataat agcatttgta ttttctcttg tagggacttt
    38461 tacgtttatg aaaataatag ggaagttaca atttaaaaat ataatctttg taccattagt
    38521 aggtataatg tttggaaata taataggttc tatgacggat tttatcgcgt ataaatacga
    38581 tttgagtcaa aatgttagtt cttggatgca aggtgacttt tctatgatac ttaaaggaaa
    38641 ttatgagata ttatatatca caatacccct tataatatta gcatatattt atgcaaataa
    38701 atttactgtt gttggtatgg gtatggattt tgcgacaaac ttaggtctta gttacaaaag
    38761 aattgtcaat ataggtctga taatagtagc acttgttaca gtatgtgtag tcgttacagc
    38821 tggtaatatc ccttttatag gtctaatagt tccaaatatc gtatccttgt atatgggtga
    38881 taatataaga gcaagcatat ggtatactgg tttacttgga gcgatatttg tacttatatg
    38941 tgatattttt ggaagaatta ttatttatcc atatgaaata tctatagggc ttacagttgg
    39001 agttatagga agtatactat tcctttattt aatattaagg aggaatgtga atgaagctta
    39061 gtctcaatca aaaaatttac tttgtaagta tattactatt catatcaata gcacttttta
    39121 taatttatgg aatagacatg aatcatttag aatatgcatt atcacaaaga ataccaaaaa
    39181 tatttgctat ggtattaggt ggaggatgta tagcatttac tactgtagtg tttcaaacaa
    39241 ttacaaacaa tcaaatatta acaccaagtg tactaggttt agattcattg tatgtaatga
    39301 ttcaaactat aatagtattc atatttggtt caagcagtag tctgattata aatgaaaatt
    39361 ataattttat tattaatgta gctatgatga ttggagcttc attgttatta tataagacgt
    39421 tatttgaaaa aaataaaaat aatattttct ttttaatcct agtaggaatg atatttggaa
    39481 ccttatttaa aagtgcaaca acatttattc aggtaatgat agacccgaat gaatttttag
    39541 ctttacaaac tagtataatg gcaagtttaa acaatataaa cactaatgta ttgttaatag
    39601 catttataat aattattgcc ataatacctt ttatatatga tgaaataaag tatttagatg
    39661 tattgtcgtt aggtaaagaa caagcaatta atttaggtgt agattttgat aaagcagtta
    39721 aaaaaatgat aatattaata gcaattttag tctcaatatc aacagcactt attggaccta
    39781 tgacattttt aggactttta cttgctaata taacaagaga aatttttaaa acatataagc
    39841 atacatactt gatttcgggt tctatgttga tagggatgat tacattgata ataggtcaat
    39901 tttttataca acatgtattt aagtttgata caactttaag tgtagtaata aattttatag
    39961 gaggaattta ctttattcaa ttactattaa agggggcaaa tagatgatag agataaaaaa
    40021 tatatttaaa agatataaga ataaaaatgt tgtagatgat gtctctttta gtatagaaaa
    40081 gggaaagata acatctttta taggaccaaa tggagctgga aaaagtacag tactatcaat
    40141 agttacaaga cttataggag gtgatggtgg agaagtaata atagaaggaa aaagcttgac
    40201 taattatagc aataaagaat tagcaaaaaa aatagctatt cttaaacaat ctaacaatat
    40261 aactttaaag cttacaataa gagaattagt tggatttgga agatttccat atagtgaagg
    40321 taatctaact aaagaggatg aaaattatat tgatgaagca atagaataca tgaagttgac
    40381 tgatatacaa cataagtatt tagatgaatt gagtggaggt caaagacaaa gagcttatat
    40441 agcaatggta atagctcaag atacagagta catattactt gatgaaccac tgaacaattt
    40501 ggatatgaac cattccgtac agatgatgaa ggtacttaga ggtctttgtg atgagttaga
    40561 taagactata gtattagtaa tgcatgatat aaattttgca tcatgttatt cagataatat
    40621 agttgcatta aaaaatggaa aagttgaaaa agtaggtcgt acagatgaga tagtaaatga
    40681 aaaagtttta gaagatattt atgagatgaa ttttaacatt aagaatataa atggaaatcg
    40741 aatctgtatt tatttttaaa atattgtata tgaaaataaa cttgctatat gattttttat
    40801 aaagttttta aattaaaata aagattaata ggagagagga aaatattgat atgaataaaa
    40861 aagcagcaat agtagcagca gtagctatta taggattagt gacagtgttt gcattaggtg
    40921 gaagtaaaaa gaatgaatca aaaacatcag aaaactcaaa taatactatg aagataactc
    40981 ataacttggg agaaacagat gtaaaattaa atcctaaaaa agtagtagta tttgattatt
    41041 cggctttaga tacaatggat gcattaggtg tagctgagaa tttagtagga cttccaaaag
    41101 cgagtttacc agcatcctta gaaaaatata aggatgacaa gtatgcagat ttaggaggat
    41161 taaaagaacc agatttagag ggtataaagt cggcaaatcc agatttaatt ataataaatg
    41221 gaagacaaga agatttttat gagcaattgt caaaaatagc accaacaata agtacaagta
    41281 aagatgataa gaagtactta gaatctgtta aaaataatat agacaaaata gcaaaaatat
    41341 ttggagtaga agaaaaagca aatcaagaat ttagtaaaat tgaaaagaaa atagaaactt
    41401 tgaataaaaa agtaacagat aaaaatttaa atgctttaac tataatggta aatgaaggta
    41461 atttaagtgt atttggtgaa gaatcaagat ttagtatatt atacaatagt tttggatttg
    41521 aaaataaaga taaaaatata aaagaatcaa gtcatggaca aaatattact tttgaatata
    41581 tagctaaaca aaatccagaa gttatgttcg ttatagatag aggaatagct actggcagtg
    41641 atgtaaaaga aagctcaact gcaaaatctg ttttgaacaa tgatataata aaatctatgg
    41701 atgcatataa gaatgataat ataatatatt tagattcacc aacatggtat gtaaatgatg
    41761 gtggtctaac atctttaaat aaaatgatag atgatgcttc aaaagcggta aattaataat
    41821 ccgatataat taatcaaaat gtatttttta taaaatgatt atcaaataaa ctaggagttt
    41881 ttaagaactc ctagtttatt ttttgcataa aaaagatgta gtttaaacaa taatattatc
    41941 tataataaga taaatctatt caaaatctaa taaaatgtga agttatacta gacaaaaaga
    42001 ataactctta aatat
//
LOCUS       DAEPUT010000033        40536 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.034, whole genome shotgun sequence.
ACCESSION   DAEPUT010000033 DAEPUT010000000
VERSION     DAEPUT010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40536
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.034"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..406)
                     /locus_tag="KRL22_001843"
     CDS             complement(<1..406)
                     /locus_tag="KRL22_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1272337.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNN"
     gene            899..1759
                     /locus_tag="KRL22_001844"
     CDS             899..1759
                     /locus_tag="KRL22_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1272338.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(1998..2555)
                     /locus_tag="KRL22_001845"
     CDS             complement(1998..2555)
                     /locus_tag="KRL22_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1272339.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(2745..3632)
                     /locus_tag="KRL22_001846"
     CDS             complement(2745..3632)
                     /locus_tag="KRL22_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1272340.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     ATRFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            3751..4950
                     /locus_tag="KRL22_001847"
     CDS             3751..4950
                     /locus_tag="KRL22_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HBH1272341.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(5144..7699)
                     /locus_tag="KRL22_001848"
     CDS             complement(5144..7699)
                     /locus_tag="KRL22_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1272342.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLDLNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(7696..8382)
                     /locus_tag="KRL22_001849"
     CDS             complement(7696..8382)
                     /locus_tag="KRL22_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272343.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     IVVNTGGEVL"
     gene            complement(8459..9367)
                     /locus_tag="KRL22_001850"
     CDS             complement(8459..9367)
                     /locus_tag="KRL22_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1272344.1"
                     /translation="MFILAFIICTVVIFIVSTKINQRRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(9369..10040)
                     /locus_tag="KRL22_001851"
     CDS             complement(9369..10040)
                     /locus_tag="KRL22_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1272345.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            10302..11366
                     /locus_tag="KRL22_001852"
     CDS             10302..11366
                     /locus_tag="KRL22_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HBH1272346.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            11524..12210
                     /locus_tag="KRL22_001853"
     CDS             11524..12210
                     /locus_tag="KRL22_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1272347.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKGNYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLIIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            12200..13231
                     /locus_tag="KRL22_001854"
     CDS             12200..13231
                     /locus_tag="KRL22_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1272348.1"
                     /translation="MNFKKFSFNSIYLIIAVGIIFTAILFSISIYLITDDLKLIALLL
                     IYTIVLCGFITLIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMIKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTSSNGKIRVATECWVMYTKIDII
                     DNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            13313..13978
                     /locus_tag="KRL22_001855"
     CDS             13313..13978
                     /locus_tag="KRL22_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272349.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMSDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDIPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            13991..16408
                     /locus_tag="KRL22_001856"
     CDS             13991..16408
                     /locus_tag="KRL22_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272350.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKNKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     SYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(16589..17369)
                     /locus_tag="KRL22_001857"
                     /pseudo
     CDS             complement(16589..17369)
                     /locus_tag="KRL22_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(17402..17989)
                     /locus_tag="KRL22_001858"
     CDS             complement(17402..17989)
                     /locus_tag="KRL22_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1272351.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(18166..19557)
                     /locus_tag="KRL22_001859"
     CDS             complement(18166..19557)
                     /locus_tag="KRL22_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HBH1272352.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(19747..21045)
                     /locus_tag="KRL22_001860"
     CDS             complement(19747..21045)
                     /locus_tag="KRL22_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HBH1272353.1"
                     /translation="MKVNVYNVESFVDERLKIMVSNLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLEALKIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            complement(21404..22279)
                     /locus_tag="KRL22_001861"
     CDS             complement(21404..22279)
                     /locus_tag="KRL22_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBH1272354.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(22472..23158)
                     /locus_tag="KRL22_001862"
     CDS             complement(22472..23158)
                     /locus_tag="KRL22_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBH1272355.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(23207..23740)
                     /locus_tag="KRL22_001863"
     CDS             complement(23207..23740)
                     /locus_tag="KRL22_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH1272356.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(23784..24416)
                     /locus_tag="KRL22_001864"
     CDS             complement(23784..24416)
                     /locus_tag="KRL22_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBH1272357.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(24506..25585)
                     /locus_tag="KRL22_001865"
     CDS             complement(24506..25585)
                     /locus_tag="KRL22_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBH1272358.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(25718..27064)
                     /gene="pepV"
                     /locus_tag="KRL22_001866"
     CDS             complement(25718..27064)
                     /gene="pepV"
                     /locus_tag="KRL22_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBH1272359.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(27133..28413)
                     /locus_tag="KRL22_001867"
     CDS             complement(27133..28413)
                     /locus_tag="KRL22_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HBH1272360.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(28540..28800)
                     /gene="hfq"
                     /locus_tag="KRL22_001868"
     CDS             complement(28540..28800)
                     /gene="hfq"
                     /locus_tag="KRL22_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBH1272361.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(28914..29849)
                     /gene="miaA"
                     /locus_tag="KRL22_001869"
     CDS             complement(28914..29849)
                     /gene="miaA"
                     /locus_tag="KRL22_001869"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBH1272362.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKGKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(29887..31854)
                     /gene="mutL"
                     /locus_tag="KRL22_001870"
     CDS             complement(29887..31854)
                     /gene="mutL"
                     /locus_tag="KRL22_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBH1272363.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVITLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(31865..34708)
                     /gene="mutS"
                     /locus_tag="KRL22_001871"
     CDS             complement(31865..34708)
                     /gene="mutS"
                     /locus_tag="KRL22_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBH1272364.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KKYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSLNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(34868..35602)
                     /locus_tag="KRL22_001872"
     CDS             complement(34868..35602)
                     /locus_tag="KRL22_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272365.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(35571..36584)
                     /locus_tag="KRL22_001873"
     CDS             complement(35571..36584)
                     /locus_tag="KRL22_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1272366.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDDRLDYYTPLIISNETVLKNNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(36606..37376)
                     /locus_tag="KRL22_001874"
     CDS             complement(36606..37376)
                     /locus_tag="KRL22_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272367.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(37351..37641)
                     /locus_tag="KRL22_001875"
     CDS             complement(37351..37641)
                     /locus_tag="KRL22_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HBH1272368.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(37772..37871)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      38491..38580
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            38633..38809
                     /locus_tag="KRL22_001876"
     CDS             38633..38809
                     /locus_tag="KRL22_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272369.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(38924..39280)
                     /locus_tag="KRL22_001877"
     CDS             complement(38924..39280)
                     /locus_tag="KRL22_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272370.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLEIDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            39536..40448
                     /locus_tag="KRL22_001878"
                     /pseudo
     CDS             39536..40448
                     /locus_tag="KRL22_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816618.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
BASE COUNT        13813 a         6279 c         4710 g        15734 t
ORIGIN      
        1 tattattttt aattgtatta aagtatacag ttccattact tgaattattt tggttagcta
       61 atgctaataa ttcagaatta gaataataat ctttatgctc ttttggttct aaaaacccat
      121 aaactctatt tccactagaa tctaaaattt gcaaccacaa ttgattttct cgaagttttt
      181 ctaatccaga ctgttttact tgtggcttat tatctataaa tacgatttgt tcattaaagt
      241 tttctgtaaa ttttttcggc cagtcactac gaataaattc cccatttggt ttctgaatag
      301 taataagtga taagaaaata cctattactg tcaggattaa gcaaataaaa atcatgaaaa
      361 aaataatgta tgaatgaaat actgttttat aactaggttt atgcatttaa tcaactcttt
      421 tcttaaactt ttattttgat tgttgcttat ataaaataga caataattat tgatatgtaa
      481 aaatttattt aaaaatacaa ctatctacat aaattatatt tatataatta tatgttatca
      541 agctgtctgt tgtatttaat aaatcctttt gataacatat aaaagtaaga taaatttttc
      601 cattaaatac cttataatta tacacaaaat ctctatatac gttaaacagt atagagaaaa
      661 ttttcataga accatcttta taggggatac tttataaaag aataaaaaaa ttataatata
      721 taaaaacttc ataggagtgt aacaacatca gtaaagatat gaaaacacta tataaaaatt
      781 caaaaatatt aagaataatg aaatacttga aattgcttat atcaagaaat tttatataat
      841 ataaactggt caaatatgtt ataatattaa attgtgacaa gttcatggag gtgtttatat
      901 gaaaaaacaa aagtcgccaa ttttacttga aatgcttgga ctattttttg gttgtatatc
      961 aatgagtatt ggtataaata tgtttttaaa accacataca attgctcctg gaggacttag
     1021 tggtctatca ttagtactaa acaaggttac aggacttcca gtatcagcta tcatgttaat
     1081 tataggtgtc ccattagtaa tacttgcttt tagaattatg ggtacaaaaa attcattaaa
     1141 aactttattt ggaacagttg tattttcagc tatagttcaa ttaacagacc cattatcaaa
     1201 actaagattt actaatgact tattattgtc ttctattgca ggaggaatcc tagttggtat
     1261 aggtttagga ataatgttta aatcagatgc ttctactgga ggaacagact taattgcact
     1321 catacttagt aagaaattcc caggaataaa agctacaaaa ttcatgtcat gcctagatgg
     1381 aatggttgtt atatcttctg gtatagtaaa tcgtagttta gaaactgctc tttactctgg
     1441 tatagcactt tgtgtattaa taaaaatagc agatatgata atggaaggat ttgaccattc
     1501 aaaagcattt tttattatct ctgatgagcc tgaaagttta agacaagcta taactgaaga
     1561 acttgataga ggtcttacta ttcttgatgg taaaggtgga tacactagag aaaataaaga
     1621 agttctatta gtcgtagttt ctaaaaaaca agaactttat ctaaagagat tagttaaaag
     1681 aactgaccct actgcatttg ttattgttac agatgtacat gaggttcttg gagaaggatt
     1741 taaaaattta gagaactaat aaaaattaat attttaagta tatatactat tttaattaaa
     1801 atacgattta ttcaaaaaga gtgtctcata aactttttag ttcatgagac attctttttt
     1861 gtataaaatc aaatgcattt tcagtatttt aacaataaaa acaggattat ctatattttg
     1921 aggcaaccac tttattgaaa ttttatttag aaaacaatca ttactaaata accagcatag
     1981 atattaaatg attatatcta ttgttttttc aattcatatt gataacaagg aacatttttt
     2041 acagtatttc cagtatgaat ttttttgata tactttcctg tacatttaaa tcctaataaa
     2101 tctaatgatt ttgtagaatt ttggttttct tcataggtta ttgcaattat tttatttaag
     2161 tttagttctc taaatccata ctgtattact ctttttgtta tctcagtagc aaaatcatgt
     2221 ccccaatagc ttggatttat acatatacct atttctgctt ctaatgcttt aggatttata
     2281 ttattaaacc ccatatttcc aataacttta ttgtctcttt tatatactat agcaaagtgg
     2341 ccaattttcc cttttttata tggatttaga aaaaatgatt ttataaactt tcttgtatct
     2401 tctaaagatt tatgctcact aaatggtaaa tgttttacta ctattttatt tttataacag
     2461 tcaaaaaaat cttcaacatc atctaatgat gcaggtctta gtatacaact tctagtttct
     2521 aaggttttca tttgaggata ttcagaatca gacatttcta atcccccttt atacattaat
     2581 ctaaatatac tgttcatatt taaaatacga tattaattat ataaatgttc tcaaattaac
     2641 cttattttta tttttaataa aaactaatta ctatatgaat ctttcaaatt tacgaattta
     2701 tctctatttt tatattaaat tacttgtgaa atatgtattc taaattatat attattagat
     2761 atcatgctta aaaattcttt ggttgctaag gataaagata tatcttttaa atggcagtaa
     2821 cctatatttc tcttaggtat tggctctttt atatctaatt taaacaattt ctcattttcc
     2881 aaataatcta tgctaaattc ttctataaca caagacactc caagatttat atacgcaaat
     2941 tctaaaagta attcatgaga acccaattct atatctgggt ttagttttat accttttgat
     3001 aaaaaatatt catttacata aagtcttgaa tttgctttat tttctagcat tattaaaggc
     3061 aatgtgttta attcttccaa tgatattttc ctacctttgt attctatgta atcatttgca
     3121 catacaaata tatcatgtat ttcaatacac tcaacaatat ttagtgtatc atcttctatt
     3181 ggcatgttta taattgctat atctatattc ccatctttga gtaaagatat aagttctcta
     3241 ctcgttctat ttattgtaga tacatgtata tgtggatact tcttatgaaa aatttctaaa
     3301 tattttaaca agaaaaaacg tgtagctgta tctcctactc ctattttcag agaaccgtat
     3361 tctaattttt taaatttatt tattctatct tctcctgatg atattaactt taatgcagta
     3421 gtgacatgtt cacttagaat tttcccctct ggagttaatt ttactccctt attatttcta
     3481 taaaataata aagtatctaa ttgttcttct aattgcttta ttgactggct tacagctggc
     3541 tgtgacataa acaattcctt agcagcaaga gaaaagctct tattatttac aactgcatta
     3601 aaaaccttat aaagttcaag ttttatattc atatataatt actccttatg tcaaatatta
     3661 gtattattta ttttacttat aattatattt gaattataat atacatggta ctaatatgac
     3721 aatattaatt ctttaggagg attttagata atggatagat tagttggaac tgtttcaaga
     3781 ggggttagag cacctattat aagacaagga gatgacttag ttaaaatagt tgttgattct
     3841 gttttaaatg cgtcaaaaag tgaaaacttt gaagttaggg acaaagatgt aattgccgtt
     3901 acagaagctg ttgtagctag agcacaggga aattatgctc acgttgacaa tattgcaaaa
     3961 gatgtaaaag ataaatttgg agatgatact gttggagtta tattcccaat tttaagtaga
     4021 aatcgttttg ctatatgttt aaaaggaatt gcaaaaggat gtagaaaagt cgtattaatg
     4081 ttaagctacc cttctgatga agttggaaat cacttaataa gtattgatga acttgatgat
     4141 aagggaataa atccttggtc agatgtttta acagaagaaa aatacagaga actatttgga
     4201 tataacaagc atacatttac tggtgtagat tatgttgatt attataagaa tttaatcaag
     4261 gattgtggtg cagaggtaga aatagtattt gcaaacaatc caaaaactat tcttaactat
     4321 acaacaagta ttttaacttg tgatatacat acaagacaaa gaacaaagag aattttaaga
     4381 caaaatggag ctaaaaaagt atattcactt gatgatataa tgacagcaag tgtagatggt
     4441 agtggttaca atgaccagta tggactttta ggttcaaaca aagctacaga agaaacagta
     4501 aaattattcc ctataaattg tgatgaagtt gtaaacaaaa tccaaggtaa tataaaagaa
     4561 ataacaggga aagatgtaga agtaatggtt tatggagatg gagcttttaa agaccctgta
     4621 ggtaaaatat gggaattagc tgacccagta gtatctcctg cttatacaaa agggctagag
     4681 ggaactccaa acgaagtaaa attaaaatac ttagcagata atgattttgc tgacttatct
     4741 ggtgatgagt taaaagaagc aatttcaaaa tacatagttg aaaaagataa taaatctgat
     4801 gatttaacag gaaacatggt ttctcaaggt actactccaa gaagattaac agaccttata
     4861 ggttctttag cagatttaac atctggaagt ggagataagg gtactcctat tatttacata
     4921 caaggatatt tcgataacta tacaaaatag tatgttttaa taagatttaa attttttgga
     4981 ttatatatat taacatgaaa atttattaaa acctcttaat agatatgact tttcaagagt
     5041 tatatctatt aagaggttta tttaatgttc acagataaga tatatttaaa taatttaaac
     5101 aagattgtca gaaagttata taatcttaaa aatttatata actctaattc ttatttattt
     5161 ctgaaataat atcactcttc aaaatttgtc ttactggaat aattacagca actatactaa
     5221 tagtgatatt taaaataatc atacctatgt ataaaggtgt atttatttta agaattggat
     5281 ttatatataa atatacacgt tttaccataa aataaatcat aaattgtcca ataacacttc
     5341 caattaccat tataatactt gcatagaatc catataaaaa accttctctt atcatcataa
     5401 gtaaaaactt attatccgta atacccatag ctcttaaaat tccaaactca tgtcttcttg
     5461 aaaaaattaa gtagcttact gtattgatta tatggaacaa acttattgca agaagtacaa
     5521 atacaatacc atatataaat aagagttttt gatttaagta ggtattattt ttttcaatag
     5581 caatggtata atctgttacg atacatcttt ttacatcact tacaacactt tttatgttct
     5641 cagacaattc ctcactgtta ctatcttctg tcttttttat acttactgaa ttataatttt
     5701 cgatatcaaa gttatttttc atttgcccat tcgtcataac tatatccata ccataatcac
     5761 caatgaaata tatgttattt gccatcacac gttttacagt agcagcaact acaaattctt
     5821 ttgttgtata atcattcttg ttttcttctt taaatttaac aatttcatct gttggtttca
     5881 ttgtctttgg cactttaact tttattgtgt ctcctggatt tatatcaact gcatcataca
     5941 tcccagttcc atccataggt agtctaacta taaccttatt atttttaacc atatcatggg
     6001 tattaatctc cccatctata atataagaat ttaatccttc taacatacca ttgttataac
     6061 cataaatatt tgtttttaaa agatagccac cttcattttg ctttgtacaa ataccatcaa
     6121 aaaaagtctt tatcctgtaa tctttttcaa gaggtttaaa gaaatttttc caaaatagtt
     6181 gttcttcttt aatttgcata gctccaaata aatatcttac tggatagact tttgatattc
     6241 cctcaacatt gtttaatctt gaaattttat cttttggtat acctacatca aaatctgttg
     6301 tttgcatagt tatttggtag tcagaattta aaccatcatc agctttcatt gtaagttcat
     6361 tattattttt agtaagctgt atagagtaac tagaacataa aaatataatt ccaccaagtg
     6421 ataatgaaaa caaaattcca ataaacattc cctttttttg agtcatgtat ttatgagata
     6481 atacttttgt catgttagag tgttttacac tttctaatat tctctttttc ttattagtaa
     6541 tcttaaagtt tttcatagat tctatactag agtatttatt caactgatgt acaacacgta
     6601 cagcaattaa aattaacaac aataagataa ataaaaagcc taaataaata gatttttcac
     6661 ttataaaaaa tgctcctgga acaatatcac tactcaaaaa tatatgtgga aattgttcat
     6721 atattgtaga cgctactcca atacctaaga agcaacctat aggaaatcca acaataaaaa
     6781 gtaaaaataa ctctaaaaat agtagaaata aaagttgttt attattagcg cctaatactt
     6841 ctaaaacccc atattgtgat attctctgaa gtattgaaac atggaaaata ctatatactg
     6901 ctgctgcacc aaacactcca acaagcaata taattgcatt tgtatttaga tctaaatttt
     6961 ttaagaactc aaatatatta tatttttcta tattttttgg tggttttact ccaaattcaa
     7021 ctgaaagagg ccagtttata taagtttttt cttttgatat gttgaatttt ttcataaatt
     7081 tataattttg ctttttaata tttttatttt catcatattt tacataaact atataagaat
     7141 ccttttcttt aggctgaaaa taatcgttta caaatccctc cagagcagtt tctgggtttg
     7201 aaagacttga taaaatacca cataacttat agattttacc atctaaattg atttctgttc
     7261 caatttcttt gtttacattt aaattgttta gagaatatgt gtcaagtact atctctccat
     7321 ctttactagg aagagttcct tttaataatt ttctacctgt catatctaaa tatgaagaat
     7381 cagcatttaa aaattctata ataaaaggtt catctatctg atttttaggt tttgtaacgc
     7441 caagtctatc tacagtgtat tcctttgatt ttttattttc tttaatttta ttaagttgtt
     7501 ccttatctac tttatagaaa taatgataat ctccactatc ttcccttatc ttttcaattc
     7561 tacttttgtc tgcactatga actaaagaac caatccccgt caataatgct actgatagta
     7621 ctatgcttaa aactatagat atagattgtt ttttataatg ctttatatat tgaattgaaa
     7681 attttactag agacatcata gtacttcacc accagtattc accacaattc catcttcaat
     7741 atggataatt gagtcgcata cttgtgctat attttcattg tgtgttacca taagtatcgt
     7801 ttgatggaat tttgcactac tttcttttaa taaacatacc acttccattg tagttttact
     7861 atcgagattt cctgttggtt catctgctaa tataagcgca ggtttatttg ccaaagctct
     7921 agcaattgct accctctgtt gttgaccacc agatagttcg cttggaaatt ttaaacgctt
     7981 atcccaaatt cccaatgtct tcatcagcat ttcaatatat tcatggtcta tatggtttcc
     8041 tttatctaat gtaacaggaa gagctatatt atcataagtg tttaatacgg gcattaaact
     8101 gtagttttga aatataaatc ctatatttct tcttctaaat actgtcaaat ctttttttcc
     8161 tattttagat atgttctttc ctttaattat tacatcacct gaagttggat tatctaatcc
     8221 acctataata tttaacaatg tgctttttcc agaaccagaa gttccaacta tagcagtaaa
     8281 tgtatctcgt tcaatttcta tacttactcc atttaaggct tttactttag tctcaccttt
     8341 tccatagtgt tttactaaat tattcgtcac taatatactc atttaatttc tcctttccat
     8401 acagatatat gttctataaa atattgtaag tgacgataat tacactcatc ctacaaaatt
     8461 agtttaaact cttacaattc tgtaagaaga tactaaaaca acatccactt cctagtttag
     8521 attctactat aatgtttcca ttttcttttt ctaaaattaa tcttgtaaga tatagaccaa
     8581 tccctgtgcc attttggttt tccacatttt tacttctgta aaatctttta aaaatatcat
     8641 ttagttctct actatcaata cctattccct catctttaat agtaatcttc gtatatagtt
     8701 ccatttttat tacagaaata gtaatcgtgc tatctgatgg tgagtatttt attgcatttt
     8761 ctaaaacatt tacaattgct tctatggtcc actttttatt atgaactaat tttatgtctg
     8821 aaaatggttc gagatttatc cttatatttt tagcttctgc tttattaaag atagtactga
     8881 tactttgaat aagagtatct ttaattagta gttcttctac ttcaaattct ataactccat
     8941 cctctaattt agtcatttta aataaggatt gtaacagcca gtcaatctta aaagtttcat
     9001 ttttcatctt ttgtaaaaac tccttcttct gtaatgtgga aatatttata ttctccagaa
     9061 gttcacaata aatggttata tttgaaagtg gagtttttaa ttgatgtgac atatttgata
     9121 ttaaaccttt aatcgcttct ttttctgact ttgactgttc tacttctatt tctatcatat
     9181 ccttaatttt ttttacttgg tgagaaattt ttgacgctct tgtatccttc gtatctggat
     9241 aagtaacttc tttaccttcc aatatttgat ttaacatcaa atttaattca tcatatcttc
     9301 tttggtttat tttagtagat actataaata taacaactgt acatattata aaggctaata
     9361 taaacatatt attctacctc attccataaa taacccattc cataagctgt ttttatatat
     9421 tttggattag atgggtcatc ctctactttt actctaagtc ttcttatatt tacagataca
     9481 atattatcat caacataatt ttcttcgctg tcccaaatat ggtgtaaaat ttgttccttt
     9541 aataatattt gacctttatt ttcaattaga taacttagaa gcttatattc tacagagcta
     9601 agttccaaac attctttatt tttatatact tttagtaact tttggtccaa ttttattcca
     9661 ttggaatata ttactttatt attcgatttt tttcttattg ctactttgac tcttgccttt
     9721 aatacagata aagaaaatgg ttttgtaata taatcatcaa gccctatttc taatcctttt
     9781 acttcatcaa tttctgagtc tcttgcagta agcattataa ttggtatatc tgacttttcc
     9841 cttattattt gacatacatc aaatccatct ccatctggaa gattgcagtc taagattata
     9901 aaatctatat ttttactatt aaatatattt aatccttctt gttttgtata agccttaaat
     9961 acattaaatc catcattctc aaatgcataa aaaagacctt catttaagtt tatatcatct
    10021 tcaataatta ataagttcaa ttttactctc ctttagattt tttagataaa taattatttt
    10081 cttgcattat catactaaaa atattttaat tttatttatt tcactaaaaa gattgtattt
    10141 aaatttgttt tcaaaataaa aacatcataa tcaagcatat agttatatat ttcccaattt
    10201 aattacgctt aaattgaaaa tataacttta ttcttatata attaaattat acaacaataa
    10261 agttatattt tttaaatata tttttactag ggggaataga attgaaaagg gttgatgaga
    10321 gaaatactat gtttgcaaga gcaaattaca aaaaagatag tactgcttat aatgactatt
    10381 ataagaaaaa tcctgacaaa aaagaaattg atgatagtat aagaaataga ccaaatttat
    10441 gtagtgaagg aacaatgact tacaatgagt taaactctcc aatggcaagt agtgcattcg
    10501 attttttatc tgatatcaaa tctttatgcg aaggaaaagt ttctgatact aaagtagatg
    10561 tagatgcaaa gtcaatgaca aaaaaaatta agggtcttgc aaagcagtat ggagcttctg
    10621 tagttggtat aactaaatta aaagactatc atatttatac aaataggggt agacatgaag
    10681 aaaattacgg tgaagaaatt aatctaactc ataagtatgc aattgtattt ggatgtgaga
    10741 tggataagga aatgataaat agagctccaa tgatatgtga agttatagaa acatcaaagt
    10801 gctatgtgga tgcatctatc gtcggcatga ttttaagtta ctatataaga aatttaggat
    10861 atgatgctag aaatcatatg gatgctaatt atttagtaat gcctgttttt atagctcgtg
    10921 atgctggttt aggagatata ggaagaaatg ctatacttac aaataaagat tatggctcta
    10981 gacttagatt aggtgttgtt actacagata ttcctctttt agaagatgaa tatgttgatt
    11041 ttggactaga agatttttgt aaggtctgta aaaaatgctc ttttaactgc ccttctcatt
    11101 cgctttctaa tgatattaaa attggtgatg atggaaaata taattgggta attgaacatg
    11161 agacatgcta tattaaatgg agatatttag gtacagattg tggtatgtgt atatctgctt
    11221 gcccatttag ccaaaatctc gaaactataa agaatactac ttcatttaag ggtaataatg
    11281 agcttattca aaaagcttta gatgagtata cttcaaaatt tggtaaaaga atatttatac
    11341 ctggaaatcc atcttggttg aaataatttt atttaataaa gaatctgtac tagaatttat
    11401 cataggacag gttctttatt aaatatataa gtttttaaat actttttctc gtttataaca
    11461 attcagcaat gtttttagtc tataattgac attataaaat attaaactaa aaggagtaac
    11521 tgtatggaaa aaatattagt agtagaagat gattctatat taaataaaac tctctcatat
    11581 aacctaattg aagatggata tataattact tcaaaattta cagctaaatc tgcactgaag
    11641 tctatttttg aatgtgaatt tgatttaata attttggata ttaatttacc agataaaagt
    11701 gggtttgaat tatgtaatga aataaaggga aattacaata taccaataat ttttttaact
    11761 gctaatgata tggaatgtga tatgattaaa ggctatgaac ttggagcttt ggattatata
    11821 acaaaaccat ttaatatcaa tatatttaaa caaaaaatta aagctttttt aaatcatctt
    11881 ataataaaaa caaaacaaga ttactatagg gatggatatc ttgaaattaa cttttctgag
    11941 ttatctgcca atataaatgg aaatcaaatt atatttacac cattagaata tcgtacttta
    12001 aaactgctta ctgaaaatcc taaaagtatt ttaacaagga aagtactttt agaaaaactc
    12061 tgggatatag atgctaactt tgtagatgaa catactttaa catctgttat aagtaggatt
    12121 agaagcaaaa ttgaaaaaga caatcttaag tatatcaaaa cggtatatgg tatgggatat
    12181 atgtggttag gtgaaagaaa tgaattttaa aaaattttct tttaattcta tttatttaat
    12241 aattgctgtt ggtataattt ttacagctat tttatttagt atctcaattt atctaataac
    12301 tgatgattta aaactaattg ctctattatt aatatataca atagtacttt gtggatttat
    12361 aacattaata atatttttac ttcataaaaa aatagttata ttttgttcta aaatatgtca
    12421 cactttagat agtatgatga atagtgaaga caatattgaa attgaattag aagaagaaac
    12481 tattttatca cgtatcaatc acaggttaat tagaatgtat gaagttattc aagaaaatcg
    12541 caatagtatt gctatagaga aagctgattt acaagaacta gtttctgata tatctcatca
    12601 aattaaaact cctattgcaa atttaaaaat gattaatact actctactaa atcaaacatt
    12661 taaaacagaa attcaaaagg attttttaat ggatatggaa aaccaattag ataaattaga
    12721 ttttttaatg caatctatga taaaaacctc cagactagag acaggtataa tcacactatc
    12781 taaaaagaaa aattcaattt atgaaacaat tgctacagca cttagtggaa ttttgtttga
    12841 tgctgaaaaa aagaatattg aagttacagt tgattgtgac ccaaatttat atataattca
    12901 tgacaagaaa tggacttctg aagctatttt taatatatta gataatgctg taaaatacac
    12961 aagttctaat ggtaagatac gtgtagctac agaatgttgg gttatgtata caaaaataga
    13021 tattattgat aatggaaaag gaatatcaga aagtcgccaa gcagaaatct ttaaaagatt
    13081 ttatcgtgaa gaagatgtcc atgacataga aggtattgga ataggtctct atctttcaag
    13141 aaaaattata tctcttcaag gtggctatat taaagttaca tcagatattg gaaaagggtc
    13201 gactttttct attttcttac ctaataaata aatttttaaa tatttcattt gtaatgattc
    13261 tgcaacattt tggttttata ctgtatttac aagatgttaa ggaggtatta ttatgagtat
    13321 tttacaagta attaatttaa agaaatatta tggacaaagt tcaaacatta caaaagctct
    13381 tgatggtgta actctatcta ttgaaaaagg cgaatttatt tctattgtag gtacatctgg
    13441 tagtggcaaa tccacattat taaatatgat gggaggatta gataatccta catctggaaa
    13501 ggttattata aagggtaagg aattatctac tatgtctgat gaacagctta caatctttag
    13561 acgcagaaat ataggtttta tatttcaaaa ttataatctt gttcctttac ttaatgtata
    13621 tgaaaatatt atcttaccaa taggattgga tggagagacc atagataagg attttataaa
    13681 tgaaattata aatatgcttt ctcttgaaga aaaattatat gatataccaa gtaatctttc
    13741 tggtggtcaa cagcaacgtg ttgctatagc tagagcactt gtaacaaaac cagctattat
    13801 actagctgat gaaccaacag gtaaccttga tagtagaact agttcagatg tactgagttt
    13861 acttaaagtg acaagtaaaa aattcaacca aacaattgta atgattacac acaataatga
    13921 aattgcacaa ctaactgata gaattattcg tattgaagat ggaaaaattg ttaactagga
    13981 ggtgtagtat atgtttagaa ataataatcg cacatttata agaaaaatag ctttaaatga
    14041 tttaaaaatt aataaactta aaacatatct ttcaggtatc attataatga tttctacatg
    14101 tttattatta acagtgacct tagtttcata taatgcttct gtagatttag ttaatgcatc
    14161 tccatatcat gctatatata aatctgtaga tgaaaaagca aaaaatatac tatataaaaa
    14221 taaaaacttt agtggcgtag gaacttacaa attaattgga agtaataaaa agacagattg
    14281 tattatgtcg attgtttatg cagatgatac agcaattaaa cttatgaatt ttcaaccatt
    14341 gaaaggcaaa ctacctacaa ataaaaatga aattgctatt tcagaaaaat atttacagga
    14401 atttggttta gataaagata ttggagatag cattaaatta aattattatg atgatattac
    14461 gaataaagaa gttcaatgtg attttattat tgttggattt ctagaaaatt attatcaaga
    14521 taatgccaag caatactata cagtcgtttc aaatgattat tttaagaata tagcttctac
    14581 acctttacaa aataaaagta atacttttga cgagtcaaga cctgatactg tagatgtatt
    14641 agttaaacta tcagaagaaa atacagagaa agattcagct tcaattaaga cacagttaaa
    14701 gaaaattggt ttatctttag gtattaagaa atataatata tacttaaatg ataactatat
    14761 tgaatcaaat ttaattgatg gtgagcagat tattacagtt ttagtagttg gaatagttgt
    14821 tcttttttct agcgtttttg ttatatatag tattttttat atttcagttg ttaattcggt
    14881 tcagatgtat gctaagttga aatcgttagg tatgacttct tttcagttaa aaaagattat
    14941 ttctctacaa ggaaatattt tgtcaattat ttttattcca ttaggggtta tagcttcttg
    15001 tataattgct tacataattc aaccattagc atggcaaatg atagctgatt tatttataat
    15061 tttaatttta tcactggtaa tgtttttaac tgttagaatt tctttattta aaccagctag
    15121 aattatttct aaaatatctg ctattgaagc catgcaatat acagaaacta aatttagaaa
    15181 aaaagcaaaa aattttagtt atataaatat aaaaaatcta gcattaaaga atatcgagtc
    15241 aaatagaaag aaaaatttga ttgcattaat atcgctaagc attagtggag ttttatttat
    15301 ttcaatcgct aatcttgcta attcaataga tttcaaaaaa caactatctc aacaatttgt
    15361 ctataacgaa gattatataa ttagcattaa gagtgataac ttatatgagc atattacaga
    15421 aatccaacaa aataatccac taacagattc tcttaagaat gaaattaaat ctattcatgg
    15481 agtaaaaaaa ttaattgaat ccaaatcaat taaaagtaat attatagaac cttacatcaa
    15541 agatagagac gaaaaacaat ttattactct aattaaaggt attacgcctg aactttcaaa
    15601 atcacttgaa gaatatattg tcagtggaaa aatagactat acacatttag attcagatag
    15661 tttaattata aataaatata gaacaaaatc ttatggatta aatttaaaag ttggagatac
    15721 agttacattt aatatcttta gtggaaatga tattattaaa aagaaaatga aaattatagg
    15781 aatcattgac aattccaata caggaggtat gttttttgct tcagacaaaa ctttagaatc
    15841 tctaacacca tataatacaa atttagattt ttctatttta atagataaaa agcattctaa
    15901 agaagttgaa gaaaagttgt taagtataat tcagaaaaat tcaaatttaa tgctttattc
    15961 atatgaagat gattatagaa tgattactag agcatttcaa tatataatta tagcttcata
    16021 catttttgtt ggtttaattt cttgctttgg tatactaaat atgaccaata ccctaataaa
    16081 cagcgtttta attagaaaaa aagagtttgc attacttcaa gccgttggaa tgacaagaaa
    16141 gcaactgcga aatatgcttt atagagaagg tctaaacata agtatcaaag ctatatgtac
    16201 ttcaagtata ctaggttatt ttggttcaaa tctactttgc acttttataa aagatgtaat
    16261 tagattagac tttattaatt ttaaattttc tatatttact attttaattt tttcattcgt
    16321 attaattggt atacaagttt tagtgactga attacttgta agaaatatag aaaaaaaatc
    16381 acttacagaa cgcttacgtt ctcagtaaga atgtatataa aaaatagcca ttttttatac
    16441 aagttttaat atgatttttt aaaagctata gggatagaaa attttgactt tacataattt
    16501 tctatcccta tacttgtttt tattttatac agatacactt acttatatct ccgagcaaca
    16561 tcaccagaga cataaacaag catattcctt attttctaaa tatgtcaatt gcatgacttg
    16621 taacccctac taaatcttca cgttcacaag tagcaaggtg atattttaaa tataatgcaa
    16681 atgcatcatc atccatagag tctactgctt cacgcatata caaagccaaa ccatctgatg
    16741 cgacataatg cagtctagtt acattaaaaa tcatcaatgt tttctttacg tacaagctca
    16801 aacaaatcct ttggttcaga cttagcagca aatgtctgtg gatcaatcaa acctttttca
    16861 atatattcag atacatcaat atttcctcta tggaacccct cgtcaatgag acagccatca
    16921 gatataacat atgcagcaaa aaccacacca ccaggttttg ttacacgaat tgcctcatgt
    16981 aaagcttgtt gtttatcttc tttgttataa agatgatata gtggtcctaa cagtaacgta
    17041 atatcatatt tattatctgg gaaaacagat aaatccatag cattaccctg agtaatgctt
    17101 atattttcat ttgattgagt atttttatgg aaaacctcta tattatgttc gactaattcc
    17161 actgcgtcaa catcatatcc ctgacgtgcc agtgtgtgag aataacgacc agttgcagcg
    17221 ccaatttcaa gcacacaatc acctgatttt atgtacttat caatgtaatg catagtagtg
    17281 agaaattcca ccattccatg ttttaatgca agtcgactat cttcatcata agtattataa
    17341 aagtcaatta agtattgttt tgtttccata atttcacctc ttctatatta gttaataaac
    17401 atcaaataga caaattccaa tctggttttt cttgtcttat aaaagctgtt aatatatttt
    17461 tcaacatttt ttcagcacta tatctatcta atgttagttt ttttgttgct gttaagacag
    17521 ctatgccatg agtataaaga aataaatcta aaaatattac ttttgcacat tccaactcta
    17581 ttccaatgct ttccgaaaaa agtcttgcct ttttttcatt gtcaatttct ttataaaaat
    17641 cattcgcctc tttcatcatc aaatctaaat catttataaa taacaactta aataaatacg
    17701 tttcttcttg agcaaattca atgtatgaaa gcggaagcag taaataaggg cttacacttt
    17761 tagaattacg ataattaaca acatactgat tataatattc atatgcaaaa gcaagaaatt
    17821 cattttttaa ttcattcatg ttttcataac aagtaaaaat tggtcgagtg gaacactgta
    17881 atttacttgc aatactcctc gcatttacag cttcaaatcc cacttctctt gtaatatcca
    17941 agactgtatt caaaatcatt tcttttgtta tctttacttt aggtggcata tatgttcacc
    18001 tctccattaa atttttataa aacacatatg ttatataact atagtaacat atcaagaaat
    18061 tatgtcaaga aaaagctttg catttttttg caattcctaa aacttataaa taaaacatga
    18121 gttgcaatta atctattaat agataacagc aactcagatt ttcctttaaa tactcttctt
    18181 tttgtctaat atttcatata cacaatcttc tattgaatta atatcttttt cttttctttt
    18241 tttagaatca attaaaatga aatacagtat aaaacctaca gcaagtcccc atgttccgcc
    18301 tttagcagca attacacctc ccataagtcc aatcaatccc ttctcaacac ctgtattaca
    18361 tagctccatt gatagctttg tacataaata tccttgaact aaaagtgtta ctgacaatgc
    18421 taatggtata agaggtgtag caatctgcgc aattggataa aagcagataa aaattgctga
    18481 aacccatact aatgtaccca taccactaaa aacagactgc atggcttcct ttccaacctt
    18541 gtacctttga gcaacacttc ctgtaagtgt cgcagctaat ggaccgcaca ttggtatata
    18601 tggagaaaat attgccataa aaatatttct tatcccactt ataacattag acctatttga
    18661 attgaaatct atatattcat cttttctatt ttcactttca gaaagtacta agttttcacc
    18721 tgttataaaa tcaccaaagg caattatgta tatcataaaa gccattggta tcccttgtat
    18781 aaataacatt acacttggaa aacctattcc aaaaggagat actgtattta tcagattttt
    18841 aaaatctact atgtaaacta aattgtcaaa actaaatcta ggaatttcta tttctttact
    18901 aaatatacct actattaaac tcactaaaat agctgatact acaccatatt ctcctaaatg
    18961 aaataaaaat ttattcttaa cttttagagt atcaaatctt tcagaaaaca ttacaaaaca
    19021 agcaaccaaa attcctactg ttatagatat aggataagaa tcaaatctcc ctttaggatt
    19081 aaactctgat attatagtcg atataccgac acccattagt attccacctt taatagaatt
    19141 tggtatctta ctaactaact ttccagctac accagttata cccattaaaa taaatattat
    19201 tcctaaatct atttgtaaag ctgttaatgc ttgtattctt tcaatgccca tgctgaactt
    19261 taacaaatat gcagttgtaa gagttataga agctgtaatc cagccaggta caactgggtc
    19321 tcccataaaa acatgcaaac agtataatat tgagttaatg atagccatac tccatgccac
    19381 ttcatagggt aatcccaaaa tttgtgtact aaggccaatt gtgcctaaac ttgtcatact
    19441 tgatattata ccttgaatag cttctggttt ctcaaatctg taatgtataa atggaattct
    19501 tatcttaaac attccaaatt ttatatgagg ttgttccctt ctagcgagtc tttccataac
    19561 ttcactccac ctttcaataa ctcttataag tttacaactt tataattgtt tataaattat
    19621 taatgtcatt aaaattagta tataacatgc aaattatata aacaataaat taaatctata
    19681 aaattgatag attttgtgca tatatagaaa gaccgcttca tttttagtta cttaaatcac
    19741 ttaatattag ttatttaaat cacttgataa aggtttttta taaaattcaa tagttctatt
    19801 ccatgattca aactgtcctt ttgaatttcc ttctacagtt ccacctgaag aaaaaatccc
    19861 tccactcata ctcatacata aagtctcctt tagaggcata atatatggaa ttggtaacgg
    19921 atgacccata ttattgtatg ttaataattc tacgttatat ggataattat tttcttcaaa
    19981 gatttttaat gcctctaaac aagcttcata actattccat atgttatctt cttttccagc
    20041 aatcataagt atatctgctt tggaattttc tatttttatt ctagcctctt ttctattctc
    20101 tgctctttta agacttttct tataagtact attaaatcca aatggaatac cttttgatat
    20161 attttttttc tgttcttcaa agaatatatc attgtctact ttgatatatg gaaatggctc
    20221 tcctttatat gaccatgatg aagtatcatt tccactcatc aatccattaa gagcttggaa
    20281 acaataaatg tgaggttgtg atactacaac ctttttaatt tgttcatatc ttgaagcaag
    20341 taaaaaggcc aattctccac cctttgatgt cccatgtaca aatatttctt tagtactggt
    20401 aatttcattt tcactaatcc actcaaatac tttttcaaaa tattctaatg gaacctcttc
    20461 taatttatct ggtaaccctt ctaaagcaaa gtatgcaact gttagtacat tgaatcctct
    20521 agatgcaagt ggagctgcta aaaggtctag agcgtctaaa tttccatcag aaccacctag
    20581 cattaaaatt gttttattat tagaattttg tttataaaat aattttccta taaactcatc
    20641 agatatgtat tttgtggtaa tatcttctga tttaaatatt ctctttaatt caacttcttt
    20701 tctttcaata gaagtttcaa atatcatatt cataattatt ggtttatcaa tagatatatt
    20761 ttctgcaaaa tttttacctt cagttttaga tttttccagc gaataaatta accccataca
    20821 attatcagcc ttataagtac cttctatagg ttcaactaaa tctaaatcta cttctccttt
    20881 ttcatttgaa caaaacactc cataagatga aaattcttct cccttgcacc atggaaattc
    20941 cattttcaca cttattttaa gtttagtatt tggaattaag ttcgaaacca taatcttaag
    21001 tctttcatcc acaaatgatt ctacattgta tacatttact ttcataatct atttctcctt
    21061 ataataatta tttatgtttt atataaaaca gctttatcta atacaacata aataaatttt
    21121 taaattaaga caccatattg actatttcat tttatcaaca cattccattt ttgtcaatat
    21181 attgtctttt ttagtaattt aaaattatgt agtctatatg aaatccagtt gatttttggc
    21241 taattaaaga taggaatgct attaggttta gaatatatat attcaaaata aaaaaccact
    21301 cattttaaga atggttttta atataaacta tttgttatta ataaggatat ttttttattt
    21361 aaatttatat aatcgaacat ctaatattta atgtttaata aaattatgca tttgcaaaag
    21421 tatatatggc attaactctt gctacatata aattctcatc actacatcca atatatctag
    21481 catatttttc aatcttttct tttgcatttt caacatcatt ttcatcgctc tccattaact
    21541 catttatata aatatccatt aatgatgctt tatattctct tatatcatag cctaaaaatt
    21601 cagtcaatct ctcaatttcc ttactaaaat ctccatcttc ttttaccaaa aattcgtata
    21661 catcttccct atatggattt aaagttatta tttgttttac tactttgcat tcgtcagcct
    21721 tcccaataaa accatcttta taattattaa ataaggcatt agattttttt atagattctt
    21781 catcaatata agaatgtacc gcagttatac gattttctat aagggcatct acaacagcat
    21841 aatgaatttt aaaacaatca ttgtataaat aattactcat tttctttatt gtcgattcta
    21901 tttctaagaa gctcgcgtgg ccattttttt tatttttatt tggtataata aaagttttat
    21961 tcaagttatt aaaaagtctc ttaaaatcta aatatttttc acaataaaca cttttaaagg
    22021 tatcgatatc tatagttata attccaaaac ttactatagt ctcaattcct ttcttaaaag
    22081 actcttctat atatttttct cctaaactta aacctctatc agatatttgc tttagatttt
    22141 gaaaactatt taaacaatct ctctcaaagt ttttagatat ttctaaagca tataatttaa
    22201 agattttcct tatcttatta taattatttt ttgtatcatc aaatctgata atagctccat
    22261 ttacatcaaa agtaatcatt gagttttaac ctccccatta gtttcatcaa taaaataaat
    22321 ttaatataaa ctttataatc ataatattaa acttatttat actataatta ttaatttgat
    22381 gataaaagct attttccttc taaataaaaa atttgtctaa agtttctaaa aaatttagac
    22441 aaatcttagg ttattactct ttaaattatt tttaaattat tccaaatacg ccaaataata
    22501 ttggtataaa tatagctggt aacaaattgg ctacttttat attcgttaat ttaagtacat
    22561 ttagaccaag tcctataatt aataaacttc cagctgctgt catttctgtg actacaggat
    22621 cacttaaaaa tccatttaaa aatgatgctc ccacacatat aataccttca tacaaaaata
    22681 cagatattgc agaaaacatt acacctatac ctaaagaagc agtaaatata attgaagcta
    22741 ttccatctat aacagatttt acaaataaag tatcatgact tcctgtaaga ccactttcta
    22801 atgaaccaac tactgccatg gctcctatac agaataataa actagatgat ataaaaccct
    22861 ctgctataga atctttttta tttcctttag aaaatttact ttgtaaaaaa gcacccaact
    22921 tatttaccca tttgtcaata tctattaatt ctcctatcag agcacctaca gctacagata
    22981 ttattgtcac taatgtgttt tttccttcta gtgctcctga tataccaatg tacaatacac
    23041 ataaggcaat tccattcatt atagtatcgc ttactctttg aggtaatcct ccttttatta
    23101 taagacctac tatacatcca cctgcaattg ctagactatt tgctattact ccaaacattt
    23161 tttctcccct cgattagcta attgaaattt atcctattat taaaacctaa acatctatac
    23221 tttgtattgg atattttaaa tattccaaaa attcttcaaa accttttcta gatatattta
    23281 cagttttagt atttatgtta ggatgaaaat ttaagtaatc ttctttaatt acatctttat
    23341 ctatgtaaag ctcaactttt ctttctgtat catttattaa tgaaaaagga tttacacttc
    23401 caggaagaag tttaagtaca ttgtatagtc tttcaggtga agcaaacgat aatctagaac
    23461 ttcctatctt atctttaagt gagtttaaat caacttgttt ttctccttta actacaataa
    23521 gataatactt atttcctttg gcatttctta aaaataaatt tttacattga cacccctttg
    23581 ttattccatc taaaatgact aattgctctg ctgtatatac agcttcatgc tctactacat
    23641 catattcaac atttaattta tccaaaatat catatatttt agtttcattc atgctagatt
    23701 cattttcatc ttgttctttt ttattattta aatcactcat acttttctcc ttaaacactt
    23761 catcataata tcattgtgag gtattattct actatagcta ttgctcttac tggagctcca
    23821 tcagcatcat tatacttaaa tggtgctgct ataaatagaa atttttctgg aacattttct
    23881 aaatttgtaa gattttctat gattattttt cctttttcaa ataaaatatg atgcacttca
    23941 aatactgatg tgtcatatct atccactgat agcatatcta ttcctatgcc ttttatatta
    24001 gtattagcta tatagtttgc agcttctttt gttaatgtag gataacctac atagtactgc
    24061 tttttatccc aaaattttga ccaacctgat ttaaatatta taaaatcact attttttatt
    24121 tcatcttcat atttttttag atattctaat tctatattct catttccctt ttcaagttcc
    24181 aatacataag cttttccaac aaaattttct atatccaact tatctagggt ctcaccttta
    24241 gtatacatat gtcttggtga atccatatga gttccattgt gagaaaatac actaattaat
    24301 gtttcttgat aaccattttc ttcaataata gctactttct tgatatctgg tctattaggc
    24361 tctgcatata caggcatgtc attatgtgtc acatgagtta aatcaaaaac cttcatcttt
    24421 atataccccc tatgttttta ttttctatta tatacctaaa ttcattttat ttctatcaga
    24481 ttttattcca ttatatacca tactactata tattttttat aaacctcaag ggatttaccg
    24541 aaaaatcttg gaaagaatta tcagtaaata taacatcttc acccaaaaaa cgtttatacc
    24601 ttccttcttc tttctttaaa gtaattctct gtttttgtga atgattatta aaaaccatta
    24661 tcttaagagg aggttttttt ctattagtct gcactctttt taacatgtat tttatgtgca
    24721 tatcagcttc aggaaatgaa tatccacaaa atattaaaag gtcagtatct cttaaagttt
    24781 tttctgtttc attccaaaca ttacttaaaa atatgtttga catattctta aaatatgttg
    24841 gtggcactat aataggttct gttaactcac cacactctaa acattttgtc tctgaactat
    24901 tttcaataag cttcatgaca ccaccttcat gtggtgtaag agttacacta ttacaaatgg
    24961 ggcaataaag ccaattcaat gacccatgta tcttatataa tttgattaat ggttcttttg
    25021 gttttctcca atttaactcc tctttaaaat ttgtaaactc cacaccataa tcaagcataa
    25081 ttggcaaatc attcttatct cttaatccag taactgtatt gtctatatgt atatcataat
    25141 ttgcactaat aaaagtagta tcaagaagca aatcattttc caaaagattt tcaactaaaa
    25201 gtttatgata tttattatct gttctaggtg tattatgaat tgcttcagcc attagcagta
    25261 ttaaatattg tcttaaaaaa cgtatactat cacttctgtt atttagattt tctagtccaa
    25321 aatttctaaa tgcttctttt ctttgttctg ctaagtctaa aagacctaaa acttcttcaa
    25381 aggtaggaaa atttgcatta tctatattat cttttactat atcaatattg aacatctgtt
    25441 taaagaaaat atacaattct ctattcattt tggtattata atttgtggga tttagttttt
    25501 taaaatattc gctaaaaagt tcattttgaa taggtagatt ctctgctgct gaagctcctg
    25561 ctcctaaaaa tattgctatt ttcatatagt tcctcctaat ataaatatta ctcctatttt
    25621 tatatccatt aaatatccat atcatttatt ttatgataca acaataaagc tgtcttttac
    25681 tagaaaaaat cctattacaa gacagcctta tattatatta aatctttaat aattcgtaaa
    25741 tagaaagagc atatatttga gtagctttta taatatcctc tactattaag tattcattag
    25801 cttggtgttc tgtttctggt tttcctggaa aaatagctcc aaatgcaaca caattatcta
    25861 aagctcttgc gtatgttgct cctccagatg aaagtggtgt tccatcaaga ccagtttctt
    25921 cttcatatac ttttctaagt gtcttaacaa gaagagtatc ttctggaaca tagattgaat
    25981 ccaagaaatc atattcttca taatttaaat tgtatttatc tgtcattttc tttaactctt
    26041 ttacaaaatc atcctttttg tatgttactg gaatccttac atctattcct gcaaattctt
    26101 tttcgttatc aatagttact ctacctatat ttactgttag tttacctgat acatcatcct
    26161 tgcaattagg aattatattg tttccattag catcttcacc aataacttct gctaaaaact
    26221 taattatatt agaatctata cctatattat taagagctat acaaagtcta gccactgcat
    26281 ttataccagt atcacttgct gctgaatgga cactttttcc aattatacag attttattac
    26341 cttcaacagt atattcaaaa tttaatttat caagttcttt ttttaattta tcagagtatt
    26401 ttccaatata gattgcttta cctggaactg catttaaagc ctttccaact gacaactcta
    26461 tatcactttt gctatcacaa gtcaaatgaa cttgtaaaag acctttctct gcatttgtta
    26521 ttgggaatct agaatctgga gtaaatccat agtttggtat ttcttcatta ttttctttat
    26581 atttatttat acatctccaa agattttctt catcagcccc aaaaatgaat cttatcctct
    26641 tattaaagtc tacatttaaa tccataagag ctttcactgc ataaattgct gatattgtag
    26701 gtcctttatc atcttgtgtt cctcttccat acaatttacc atcttctaaa acagcttcaa
    26761 atggagggta attccagctt tctaaatcac cttctggaac cacatcaacg tgaccaagta
    26821 tacctatcat tttttcacct tgtcctattt ctgcatatcc ataatatcca tctttgtata
    26881 ctgtcttaaa tcctaaagat ttacataagt ctaatatacc tcttaaagct ttatctacat
    26941 tttcaccaaa tgggcaattt tcagttgctt cagatataac actaggtatt tttacacttt
    27001 cttgtattga agaaatcatt tcatcttgta gagaatttac tttttcttta atttgctctt
    27061 tcatattatc acccttcaat tttcatcata atatactaat aaatattttg accttttaaa
    27121 aaaaaaatat gcttattttt tcagtttttt tataaattca atcgctttta aagtccccat
    27181 ttttgaatgg tcaaatgtaa gtccaccttg aaaataaaca ttataaggag gtcttattgg
    27241 agcatctgca cttaattcta tagaagaacc ttgtataaat gctcctgctg ccattatgac
    27301 ttcactttcg tatccaggca tgtcccaagg aacaggtttt acataagaat cgactggtgc
    27361 agcttcttgt ataccttcac aaaaacttat tacttcatca gcattattaa gtctaataca
    27421 ttgaataata tcacttctta agtcatcata ttttggtaat acatcatatc ctaatttttc
    27481 aaaagctctt gagcaaaaga tagctcccat tacagcctga gatactatat aaggcgccaa
    27541 gaaaaaaccc tgaagtacat ttctagttgt tccaaaagta agaccacatt cttttcctat
    27601 tccaggagaa gtcattctat aagatataag ctcaatcaaa tcttttctac cagctatata
    27661 tccacctgtc aatgcaagcc caccaccagg attttttatt aaagagccag ccataacatc
    27721 tgctccaaca tcagtaggct ctttggtatc taaaaactca ccataacaat tatcaaccat
    27781 tactatagct tctggtttaa cagactttat tacttctata gcttctttta tatcactaat
    27841 tgaaagtgat tttctccaag aatatccttt tgacctttgt atcataacga gtttagttct
    27901 atcatttatt ttgtttttaa ttccttctaa atctaagttt ccatcctcta aaaaatctac
    27961 atcatcatat gtaacaccat actctttcaa tgaacctttt tcttctctta tgcctataac
    28021 tccctctaaa gtatcatatg gtctaccagt aacagataaa atttcatctc ctggtctaac
    28081 tataccttgt atacataaag taagtgcatg tgtaccattt acaattattg gtcttacaag
    28141 agcatcttct gtattaaata ctttagaata aatttcctct attttttcac gaccaatatc
    28201 attatatcca tatcctgtag tccagttaaa gtgcatatca cttagtttag attcttgcat
    28261 agcttttaaa actttatatt gattatattc tcttatttct tttatttctt caaacttatc
    28321 ttttatttct tccattattt cttgcgatag tttaaaagta tcatcatcta ttccatagta
    28381 gtcttttaat aattcttttg tctcattaag cattttatca cctgtctctt tattatttta
    28441 tttaaacatg taaaggagac tattttacta aaacaaataa attatagttt ataagttagt
    28501 ataagtctcc tctcaatcat cttaaattaa attaattatc tatctgttgt tattattatt
    28561 gttgttttgg ttttgatttg ttagattaat atactttcca ggttgtatag ttgatacagc
    28621 atgtttataa atcatgtttt gttgtctatt atccccttct attaatatta tataactatc
    28681 aaaccccttt acaagccctt taacttgcac tccattaact aaatatatag taacaggtat
    28741 cctttctttc cttgcattat ttaaaaacaa atcttgtaaa tttaaaactg tatttttcat
    28801 tagatttgta ccctcccaag attaaattga acttctaaaa tattcctacc ttatattcta
    28861 tataagttat gacaaatttt caatattaag ttgtatactt aaaaatttat atattatttt
    28921 atagaatctt taatatataa gattatttca ttttttaatt catctatatt ttcatattgg
    28981 tctaaatcaa accattttgc tgttttatat cttttaaacc atgttatctg acgttttgca
    29041 taccttctag aatctctttt aattatttca atagcttctt cgtatgtata ttctccatcc
    29101 agatacttta atatctcttt ataacctata ccttgcattg atatcatatc ttttttaaat
    29161 cccatactta aaagtttttt tacctcttca accaatccat ttttaagcat aatatcaact
    29221 ctcatgttta ttctttgata caaatgttct ctatctctat ttagaactat tattattggt
    29281 tgatattctt cattaaattt taaatcactt gaaaaatcat tcattttctt accacttaga
    29341 caaacttcaa gagctcttat gaccctttta gtattgtttt tatggattct attagcagat
    29401 tcttcatcaa gttcttttaa cttattatgc atgtaatcta ttcccttttc agcaagttgt
    29461 ttttgaagtt cttctcttaa ttcattattg gcatcagatt gtgcaaaatc catattatat
    29521 attaaagagt ttaaataaag tcctgtgcct ccagttacta aaacacattt tcccttttca
    29581 tttatttcat gtatatattt ttttgctctt tgttgaaact ctgaaactga aaatggatag
    29641 tcaggcttaa cttcatctat aaggtaatgc ttcactcctt gcatctcttc ctctgtaact
    29701 tttgcacttc caatatccat atattcatat atttgcatag aatcagctga aattatctct
    29761 gcattcatat cttttgctaa ttttattgac aaatctgttt ttccaacagc agttggacct
    29821 gtaagtatta taagtggtat ttttttcata acattccttt ccatatattt taaatatcca
    29881 aatattttac ataattcttt taaacatttt ttctatttct gtcttagata tttcgaccat
    29941 tataggtctt ccatgaggac atgtaaatgg attctcacac ttttctagct gttccaataa
    30001 actttttatt tcaatatcgt atattttatc atttgctttt atagcagacc tacatgccat
    30061 agatgcaaat ctctctcctt ttaaatcata attacttgta atttcttcta tattatcaat
    30121 tatttgaagt ataaatttct cagtttcagg tactccaaat atagtaggaa cacatcttac
    30181 cattatatga ttattgccaa aaatttctag ctcaaaacca aatttcataa ataactccaa
    30241 gttattttca atttgaagca tatctacatt tgatacttca ataaccactg ggtctaaaag
    30301 tatttgcata tttatatctt gtctatagaa cttctccata tatctttcat atagtattct
    30361 ttcatgtgca gcatgttggt ccaacaaata catagaatca tctttgctca aaattatata
    30421 agtattaaat acaactccaa ttacagaata tccgtataaa gaaaacttgc gttttgaact
    30481 acacaagtat tcttcttcac tgtccttaat actatctcct aagtaataat ttccttcatt
    30541 tttaattcca tcaacttgaa actcttcttg tatattatca tttgcactat cttcacttag
    30601 ataattaatg ttttttacat catcttctac acttgcattt aggacttcac ttactgattg
    30661 aaattcattt attggttttt cacttgataa agtaataact tcaatgactt catccttacc
    30721 tttagtaata ttactatttt taggagtaga ttctaataaa tcattatttc ttaatttata
    30781 atctgtactt ttttctctac tgttaatagc gattctaggt tgtgtttttt tatcactata
    30841 agtagcatat tttccaataa gatttgagtg tattaattta acctttaaaa aatctctaag
    30901 ttctatatac acttcttgtt ctttttcaaa tttaatttca agtttattgg ggtgtatatt
    30961 tacatctata catgatgggt ctacttctat atttaagaag cacactgcat gtttacctat
    31021 tggaattata gacttataac tttctgttat tgcatctatg attattttac tttttacaaa
    31081 tcttttattt atatagatat gttgtaagtt tttatttgaa cggtatatat tgttattacc
    31141 tatatatcca ttcattttaa agtgattgca cttaaactct acatctatta tattttccgt
    31201 tatttctttt ccatatatac ttctaatagt gtttacaagt tttccatccc ctggagtatt
    31261 tagcatctgt ttattgttat ttgtatattt aaattgaatg tttggattac ctattgcaag
    31321 tttatttatc aaatcactta tatttatagt ttctgcatga gtagatttta aaaatttctg
    31381 tcttgctggt gtattaaaga aaatatcttt tataatgatg gtagttccat tagtagaacc
    31441 tattggttct ttcgatatta tttttccacc ttcaacatat attttagttc ctattatttc
    31501 atctttagtt ttagtcgtca tttctaattt tgatacagct gaaatagatg ccaatgcttc
    31561 tcctctaaaa ccaagagagt ataaatcata caaatcatca atttttttaa ttttactagt
    31621 agcatgtctc aaaaatgatt tttcaacttc acttgaaggt attcctattc cattatctgt
    31681 aatcttaatt agactttttc ctccatcaat tatatctatg gaaattttat ttgcacctgc
    31741 atcaatggag ttttcaataa gttcttttac tacagaagaa ggtctttcta caacttcacc
    31801 tgctgctatc ttatttatag tcaaatcatc taggatgtta attatatttt tcatttttac
    31861 acctctaaga ttttatttct tttgcttttc tttgaagatt ataaagagag tttatagcat
    31921 ctaatggagt catatttaaa atatccagat ttaaaatttc ttctgatagt atatctctat
    31981 ttagactatc aaaagagatt tgagttaagg ctacttcttt tacagaatcc tcttgattaa
    32041 ttttctcttt atcatcattt tgcttcatta aagcaacttc atcatttaat gctttaaatt
    32101 tagaatttaa tttatcataa tcctttttta tatgtttgta gtcttttact ataagttcat
    32161 gttctatttt tagagattca tatttattct taaaattact ttgatttacc ttaactaatt
    32221 cttcgtccaa attactatta attatattat tgttttcttt atctccattt attgcaacac
    32281 tgttgtaaac atgatttttt tccaagtctt taagtatata ttttgctctt tctatgactt
    32341 cgtctggtaa tttagctaat ttagcaacat atattccata actcttgtct gctccctgag
    32401 gaattatttt tcttaaaaat attattcctt ccccatcttc tttgactgct attgaataat
    32461 ttttaacctc tttaaactct tcttctaaat cagtaagttc atgataatgt gttgcaaata
    32521 atgtcttaca tctaatattt ttttgaatat attccactat tgaccatgct aaacttatcc
    32581 catcataggt actagttcca cgacctattt catctaatat aactaaactt ctctctgttg
    32641 cattttttaa tataagggat acttcgttca tctctaccat aaaagtagat tgaccttgag
    32701 ataaatcgtc actagctcca acccttgtaa atattctatc taatattgga atatcagcag
    32761 actctgctgg tacaaatgag cctatatgtg ccataagagc tattatagca gtttgtctca
    32821 tatatgttga tttacctgac atattaggac cagttattat gttaataatg ttttctccac
    32881 gatttaaata agtatcattt ggaacgaaat tttcctctcc tactatattt tcgacaacag
    32941 gatgtctacc atttcttata tcaagtttat tattttcatt tattgctggt tttacatagt
    33001 tatttatatg tgcaactgtt gcaagggaca caaaaacatc tatattagct atagtcttag
    33061 ccactttttg tattctatct atgtttttat atattgtatc tcttatctct acaaatatct
    33121 cgtattctaa agatttaatt ttttcctctg catgtagtat cttttcttct atttccttta
    33181 attctggagt tatatatctt tctgcattac taagtgtttg ctttcttata tatgtctcat
    33241 ctagctttgc ctgtttaaag ttagcttttg ttatttctat ataatatcca aaaactttat
    33301 taaatcctat ttttaatgat ttaactcctg ttttttctct ttccctgttt tctatttcct
    33361 ttacaagaaa ggctccattc ttagaaatct ctcttagttc cttaagttca tcactaaaat
    33421 ctgatttaat tatgtttcca tcttttatgg ttatcgtagg ttcttctaga atagcttcat
    33481 ctattaaatt gtatatatca tctaatttat ccatttctga aacatacttt tttaggattt
    33541 ttgcatttga taaatttata gtatctttta aattaggtaa cttttctatc gaatttttta
    33601 agtgaattaa ctcttttggt gttactctct caaatgctat ctttccacat attctttcta
    33661 tatcgtatat atttttaagt atatcattta ggtcttctct taatataaag tcatctttta
    33721 tttcttctat tacatctaat ctattttcaa ttttagattt atttatcaaa ggttcttcta
    33781 catattttct taaaagtcta cctcccattg ctgtagaagt tttatcaagt acgtgtaata
    33841 atgaaccttt tttcttattc cctcttatag tttgagtaag ttctaaatta gttctagtaa
    33901 acatatctaa aaccatatat tctgatgaat tgtatatatt tatattatta atgttagatg
    33961 ttatttgttt ttgagtattg tatatataat tcagaagaat tgataagctt gactttatta
    34021 gacctttatc atcaaacttt agtttttgta gataaacatc tggaaaatat tcttttaata
    34081 tatttatatc caaatagtta tcactaaaac tttcatttat gtatatatta cttacagtag
    34141 ctatatctct aagcttttct ataaagtcta aatcatttat aattatttca gttggatgga
    34201 tttttgcaat ttcttcaatt accttatctt catttaaaca tgttgcatta gtttctcctg
    34261 tacttatatc aacataagtt agacctatat tagtaccatc cttatacaaa gataataaat
    34321 aattattctt tttattttca agtaaatttc catctaaaac tgtaccagga gtgatgactc
    34381 ttataacctc tcttctaaca attccttttg ctgtagatgg gtcttccatt tgttcaccta
    34441 ttgctacttt atatccattt tcaactaatt ttgatatata tgaattggct gagtggaaag
    34501 gaacaccaca cataggagca cgttcttcta aaccacaagc ttttcctgtc aatgctattt
    34561 caagagcttt tgaagctact aatgcatctt caaaaaacat ttcataaaaa tctccaagtc
    34621 taaaaaacag tatacagtct ttatatctat tttttacttc aagatactgt ttcatcatag
    34681 gagttaattt attcatatct atttgcatta tcaaacctcc ttcttttcta attaaatatt
    34741 atatcatagt agatgattat tattaacaca atatataaaa ttttgacata taactaaaaa
    34801 caatccaaaa tgtatactca cattttggat tgctaagttt aatgcttatt aaataaaaat
    34861 atttttttta caataaagat attatttctt ttttaagttt aatgatattt tcaaggttat
    34921 cttcatttaa ctttctacta tctataacaa attctttctt tactattgat ggtttttttg
    34981 aaataacata aattctgttt gatagcatta tagcttcgtc aatatcatga gttataagaa
    35041 gtattgttga atttactttt ttcttaacat ctaaaagcca tttttgcatg gatgttttag
    35101 ttaatgaatc aagtgcccca aaaggctcat ctaaaagcat tatgtcatta gaatttataa
    35161 aagttctcaa gaagttagcc ctctgtctca ttcctccaga aagttctgaa ggatatttat
    35221 cttcatatcc gcttaatcca aacacctcaa aataaggttt taccattgac ctagctttac
    35281 tctttttttc tttttttaaa attagtggta gggacacatt atctattata gttttatatg
    35341 gcaagagtaa atctttttga tacatataac tatacttacc atttatattc actttgccac
    35401 tatcataatc tgtaagttta gttataatat taaaaatagt actttttcca catccacttg
    35461 gccctaatat agaaacaaac tcaccttcat aaacatcaat acttatatct tttaaaactt
    35521 caatatcttt ataagttttt gatacatttt ctatagatac ttttactttt ttattgtggt
    35581 aaaaattcat ttgtgtaagc atcacttgcc ttcatatcct tatctattaa tttatattct
    35641 tttaagaatg atgtatagtt gttccataca ctatctttca tttctcccca tcgtggtgca
    35701 tcatctttgt acttgcttgc taaatattct tgactcttta aagctagttt ttcatctact
    35761 tcaggtgcat gttttactaa aatttttgct gattcttctg gattttttat tgcatattca
    35821 taaccttttg ttgtagcttt taagaatttt ttagcaagct ctggattatt tttaagcaca
    35881 gtttcattag aaattataag tggtgtataa taatccaatc tatcatctaa atcttttact
    35941 ggtataaagt ttaagtcata tccaattaaa tcagctttaa ctgcatccca accttcaaat
    36001 atccatgcaa aatctacagt tttcatagct gcaaagaaat catcttgacc agtattaact
    36061 atctttaact tattaaaatc agctccattt ttcttcataa ctgctttaaa aacagcttct
    36121 tctgatggag agccccaacc accataagtt tttccttcaa aatctttagc tgttgttata
    36181 ttcttttctt ttggtgatgc aaacccagaa gtattatgtt gtataacagt tgctacagct
    36241 tttattggaa gtggatcttc actagtcttt gcataagtaa cttgttcttg atagcttata
    36301 ccaaagtcag cttttcctgt tgctactaaa gtttctgctc cactttcagg tggttgtact
    36361 atttcaacat ccaaaccttc ttctttatag taacccttat caagtgctac aaataatcca
    36421 gtatgatttg tatttggtgt ccaatcaagc accatagtta cttttttaga agaagtatct
    36481 ttatcattgt ttttgtcttt attgttattt gaagaacatc cagttattgt tgccaatgta
    36541 aaaacactta ctaaacctaa tattcctaac tttttaaaat tcataattgc ctccctcaaa
    36601 tacctttaat ctattaatct atgtcttata acaacttttt ttacagcctg tacaattcct
    36661 acaaacatta aactaaatat aactactaat atagtagatg caaatacttt atcaagtgca
    36721 tatgcacttt ttgacctaag catataaaca ccaagtcctt tcgttccacc tagccattct
    36781 gcaacagttg ctgccattac agcatacgtt gcagatattt taagtccaga aaaaaattta
    36841 tccattgcca taggaaattt aaggtgaatg aatgtattaa ctttatttga gtccatagtc
    36901 ttaaataaat ttaaataatc tttatcaata ttctcaatgc catctacaaa acttattaat
    36961 ataggaaaaa aacaagtaag cattaccatc aatacttttg gcattgttcc aaatccaaac
    37021 catatcataa agagtggtgc tataattatt gtaggtatca tctgtgtaac caacataata
    37081 ggataaagac atttttttat tattgataca aaatccatca atattccaat taccaatgat
    37141 attataattg cgactataaa accaagtatt gcttctccta tagtaaccac agcatgcatg
    37201 gataaatttt gataatcttt aaaaaacaca ttaattatat ctactggtgt gggtagtata
    37261 tactgaggaa cttctaaaac tcctaccata gattgccaaa gaataagtat aaacaaaaat
    37321 gttgctattg gatatatact atctttgact ttatctatga tttctaagtt tttcatctat
    37381 agtcagacct ccagcttttt catctactct agctactgtt atgactcttt cacatccaag
    37441 attaaaaggg attttatgta ccttttttaa taattcaaaa acttcatcaa aatcaccttc
    37501 aacagtagtg ctcattgctc ctatttcaca tttaagacca cttttttcaa tttcagcaat
    37561 acaagcatct actactttat acatttcttc ttcacctttg taaggtctta gtggcattac
    37621 tgctatgtct gcgattacca tttaaatcac tcctttaaaa ataattaata cctactaggt
    37681 atattttgtt ttttattaaa aaattttatt actaaaaaga tattatattt aaataaaaga
    37741 aaagtcttat ccaaaatagg ataagactta tttttatctt aactggtctc cctacactgg
    37801 cattatccaa acaggttcaa agggtcgaga taaaatctcc tctcagcaca ttagctcccc
    37861 gaaatatatt atatcttttc tacttgatta tactacactt atcatatttt aacaaatttt
    37921 ttatttatat tagatatttt atccgttcaa aaatatctaa tataaattgt acattattac
    37981 accaaataaa ttatcttaaa atggtaattt atcaacatct tccaaaacta gattaactga
    38041 attttctagt ttttattttg ctatttcaag catatttgga tgtatatcaa ttccatacaa
    38101 atattgtgct aaatttctgt tttcactaat ctaatttgca atcgttacag attacagatt
    38161 agaaatagct tttagactct acttatcttt atctacaaaa aatccttcaa taaattcagt
    38221 aataatattc agtaatctaa aaataaacct ctatctagat ttttaagata caagcctttt
    38281 aggaagtatc ttttgtgata atataaaaat tactcgtcat tatcatcaaa atcctcatca
    38341 accaacattt tatataagaa tcaaactcta taatataatt attttatcca atttattttt
    38401 gagaaataaa atattttttt aatttttaaa ttttttaata tgcaccttga aaaaagaaac
    38461 gttttcctat attatggtaa tagtagaata aaactaaata ggcaaaacta gagaaattta
    38521 gtgacgcaaa gctataggga ctaagactta tgaaatgagt tatgtcagcc agttgccaaa
    38581 gagatatttt ctttttgttt ttatgaatgt tttttagggg gatatatgat atatgtttat
    38641 ggataaaatg gatagatgta cacatatact aactgcatat atatgcagtt cacgcgatta
    38701 ctgcaatttt atagatacac aattaaatga ttttatacta gaatatggag agaatgtggt
    38761 agaatcttgt ttgcatcaag tgatggtatt ggtaagcaga tataattaaa gaaattttat
    38821 tttctagaaa acccttttta gttttatcta cgttttataa ttcattaaaa aactaattaa
    38881 aataagcttc attatatatt tttcatgaag taaacagttg agtttatctc atatactgtt
    38941 taccccaatt acataattct aataatatag attccaatga tttaccacgt ttagtagaca
    39001 aatattcaac ttttggagga atagtcggat aagaaatcct cttaataagt ccatctattt
    39061 caagatactt taattcttgt gacagtatct tatgacttat atgaacaact tcttttttta
    39121 attgactgta acgtattggc tcttgtttta aaatatgcca taaaataatt gccctccatt
    39181 tacttcctat cacagtcatg gtaaaaccaa ttgaacaatt aaaatctttt tgtctttctt
    39241 caatatttgg aaattcttca aaattattat ctatatccat ctcaatcctc tctttcaaaa
    39301 tagtaagtat ctaactaaaa agtgcattct tgtttagcgt actaattcgt aatataatct
    39361 tgattgtagt atagagcctt acataatact acttttttag atgtatatgt ttaaatttta
    39421 atatagacat atgttatttt attaatttta tttaaacaga taataataaa taataattta
    39481 tctcaagttt tctatgtaga taaactaatc taatgtttag aaaggattat ataatatgaa
    39541 taaaaaattt cgtctttatc aagttgactc attacaaaag aaaaatttac aggtaatccg
    39601 gctggtgtaa ttacaaatgc tgatggctta tctgaatcac aaatgcaaaa aataacaaga
    39661 gaattaaata attcagaaac tgcttttatt ttcaataact tggctaaaaa tcatcaagaa
    39721 aattatgatg tacatatcag attttttaca ctaactaatg aggttcctat atgtggtcat
    39781 gctactattg ctgcccatta tgttagagca gtagaaaacc aattcaataa caaaacagta
    39841 tttcaaaaaa ctggtgctgg aatattacca gttgatatta taaaaaaaga taatgattat
    39901 gaaataatta tgacacaagg aaaaattgaa gtatctccac cattacaaca aacctatcaa
    39961 aaaagattac ttaatgcatt tggtatttta aaggaagata ttcgtacaga ttgtcctatt
    40021 gccatatcat ctacaggaca ttcaaaagtt atgattggaa taaaggaatt atcaacatta
    40081 aatagtttat ctccaaattt atatgaatta tcgaaaataa gtcaagaaat aaaatgtaat
    40141 ggacattata tttttacatt acataataaa gaaactctac aagttcatgg aagaatgttt
    40201 gctcctgcaa ttggtatttc agaagaccct gttacaggaa atgctaatgg acccttaggt
    40261 gcgtaccttg tacattataa agtaatacct acacccaaca cagagtttat atttgaagca
    40321 gttcaaggag aagcaataaa cgcaaaggca agatgttagt aaaagtaatt attttagata
    40381 ataagccagt tgaagtaaaa ataattggaa aagctgtaat tgcattctca acaaacatag
    40441 aaatctaatt atagattcct tctaagtaaa tttttgaact ttttaatact aatttaataa
    40501 caaactaatt tatatacaat caaattaatt ttttta
//
LOCUS       DAEPUT010000034        40281 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.035, whole genome shotgun sequence.
ACCESSION   DAEPUT010000034 DAEPUT010000000
VERSION     DAEPUT010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40281
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.035"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..758)
                     /locus_tag="KRL22_001879"
     CDS             complement(<1..758)
                     /locus_tag="KRL22_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBH1272371.1"
                     /translation="MIDKILKDIKGLFKVQDKAKFLKQNIPYLAFFYVGNIFSHHVRA
                     YTGGDVIDKIFQGILELNTMSFLPSFHPTDILIGVGVATLIKFIAYTKGKNAKKFRQG
                     KEYGSARWGTRKDIEPYIDEKFQNNILLTQTERLTMNGRPKNPKYARNKNVLVIGGSG
                     SGKTRFYVKPNLMQMHSSYCVTDPKGTIVLECGKMLEDNGYEIKILNTINFKKSMKYN
                     PFAYLRSEKDILKLVQTIIANTKGEGEKAGEDFWV"
     gene            complement(755..1240)
                     /locus_tag="KRL22_001880"
     CDS             complement(755..1240)
                     /locus_tag="KRL22_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBH1272372.1"
                     /translation="MINEEIARKTLNMEINAGKVTGKGLLNLLKKLMKEAEKFGGLEK
                     LVNVNGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKNKETGKNSVF
                     FQAKDMKVMDKAFKHALSKSEKKAERKESIHKNIEKFKEMAKNSISKEKIKNKQKEQS
                     L"
     gene            complement(1242..2252)
                     /locus_tag="KRL22_001881"
     CDS             complement(1242..2252)
                     /locus_tag="KRL22_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1272373.1"
                     /translation="MYLFDEQPIVANKTLARELGLNEALVLQQINYWIEINKKSGKNY
                     HDGKYWTYNSIRAWQENDFDYMSFDTVKRTFSKLEKAGYLLVGNYNKDPRDKTKWYTI
                     NNDKLEELYMDMDLKKQKIQTEALKNSMPNALGQNAPMDKGKISQCNNADCTNAQVQN
                     ALMQKDNLHQPLPENTTNNTTNNSAYISIHPSIKENNQLFSENMKGGRIDISYKNIYQ
                     NCLEELRHQTGYYEHMSIGNKSVAEEFDEILKILADVMVLDDESFITINQTKISVQVV
                     KERFRKLNSGHLEYLVGVLRENEYKIRNIRAFVLTAAYNAPSGIDAYYSALVSYDMRG
                     GY"
     gene            complement(2353..2871)
                     /locus_tag="KRL22_001882"
     CDS             complement(2353..2871)
                     /locus_tag="KRL22_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBH1272374.1"
                     /translation="MRVYENKEELKTEINKTFEKYIAEFDNIPESLKDKRIDEVDRTP
                     VENLAYQVGWTTLVLKWEEDERNGLQVKTPSDEFKWNQLGELYQWFTDTYAYLSLQEL
                     KSKLNENINSIYVMIDSLSDEELFKPHMRKWADDATKTAVWEVYKFIHVNTVAPFKTF
                     RNKIRKWKKIVL"
     gene            complement(2912..3193)
                     /locus_tag="KRL22_001883"
     CDS             complement(2912..3193)
                     /locus_tag="KRL22_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272375.1"
                     /translation="MRWILKIILFPISLLLSILTAVLSFLLGIGTVILYLLMMFCIFG
                     AIASFLQKEVTIGIEALIIGFLLSPYGIPMVGASIIELLQGINEKIMSV"
     gene            complement(3212..4846)
                     /gene="rlmD"
                     /locus_tag="KRL22_001884"
     CDS             complement(3212..4846)
                     /gene="rlmD"
                     /locus_tag="KRL22_001884"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH1272376.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVALLS
                     KLDVDKHIDVEIKLDELDLTSAESKATYAQIKEYVLEKFGLKVSTLYIAQIKKKCGIE
                     MREHYNKSKKDNQAIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(5021..6781)
                     /gene="pyk"
                     /locus_tag="KRL22_001885"
     CDS             complement(5021..6781)
                     /gene="pyk"
                     /locus_tag="KRL22_001885"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBH1272377.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSATDITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(6833..7792)
                     /gene="pfkA"
                     /locus_tag="KRL22_001886"
     CDS             complement(6833..7792)
                     /gene="pfkA"
                     /locus_tag="KRL22_001886"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH1272378.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(8001..11570)
                     /locus_tag="KRL22_001887"
     CDS             complement(8001..11570)
                     /locus_tag="KRL22_001887"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBH1272379.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(11690..12673)
                     /gene="whiA"
                     /locus_tag="KRL22_001888"
     CDS             complement(11690..12673)
                     /gene="whiA"
                     /locus_tag="KRL22_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBH1272380.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKNHSNKLRGQSQNKH"
     gene            complement(12690..13115)
                     /locus_tag="KRL22_001889"
     CDS             complement(12690..13115)
                     /locus_tag="KRL22_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1272381.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(13184..14290)
                     /locus_tag="KRL22_001890"
     CDS             complement(13184..14290)
                     /locus_tag="KRL22_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBH1272382.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(14302..15159)
                     /gene="rapZ"
                     /locus_tag="KRL22_001891"
     CDS             complement(14302..15159)
                     /gene="rapZ"
                     /locus_tag="KRL22_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBH1272383.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(15190..15903)
                     /locus_tag="KRL22_001892"
     CDS             complement(15190..15903)
                     /locus_tag="KRL22_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH1272384.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(15907..16821)
                     /gene="murB"
                     /locus_tag="KRL22_001893"
     CDS             complement(15907..16821)
                     /gene="murB"
                     /locus_tag="KRL22_001893"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBH1272385.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(17094..17864)
                     /locus_tag="KRL22_001894"
     CDS             complement(17094..17864)
                     /locus_tag="KRL22_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH1272386.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            18182..19663
                     /gene="cls"
                     /locus_tag="KRL22_001895"
     CDS             18182..19663
                     /gene="cls"
                     /locus_tag="KRL22_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH1272387.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSRKA
                     LEQRIIFENDILDSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            19981..20478
                     /locus_tag="KRL22_001896"
     CDS             19981..20478
                     /locus_tag="KRL22_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HBH1272388.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            20495..22381
                     /locus_tag="KRL22_001897"
     CDS             20495..22381
                     /locus_tag="KRL22_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBH1272389.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            22404..24185
                     /locus_tag="KRL22_001898"
     CDS             22404..24185
                     /locus_tag="KRL22_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH1272390.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(24325..26121)
                     /locus_tag="KRL22_001899"
     CDS             complement(24325..26121)
                     /locus_tag="KRL22_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HBH1272391.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGLAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKDNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDIEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(26335..27264)
                     /locus_tag="KRL22_001900"
     CDS             complement(26335..27264)
                     /locus_tag="KRL22_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBH1272392.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(27264..29081)
                     /gene="uvrC"
                     /locus_tag="KRL22_001901"
     CDS             complement(27264..29081)
                     /gene="uvrC"
                     /locus_tag="KRL22_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBH1272393.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(29340..32165)
                     /gene="uvrA"
                     /locus_tag="KRL22_001902"
     CDS             complement(29340..32165)
                     /gene="uvrA"
                     /locus_tag="KRL22_001902"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1272394.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(32184..34154)
                     /gene="uvrB"
                     /locus_tag="KRL22_001903"
     CDS             complement(32184..34154)
                     /gene="uvrB"
                     /locus_tag="KRL22_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBH1272395.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(34341..35603)
                     /locus_tag="KRL22_001904"
     CDS             complement(34341..35603)
                     /locus_tag="KRL22_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBH1272396.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(35666..36970)
                     /locus_tag="KRL22_001905"
     CDS             complement(35666..36970)
                     /locus_tag="KRL22_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1272397.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(37001..37861)
                     /locus_tag="KRL22_001906"
     CDS             complement(37001..37861)
                     /locus_tag="KRL22_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH1272398.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(37905..38774)
                     /locus_tag="KRL22_001907"
     CDS             complement(37905..38774)
                     /locus_tag="KRL22_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH1272399.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(38758..39828)
                     /locus_tag="KRL22_001908"
     CDS             complement(38758..39828)
                     /locus_tag="KRL22_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272400.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        12268 a         7285 c         4969 g        15759 t
ORIGIN      
        1 acccaaaaat cttcccccgc tttttcaccc tctcccttag tgtttgcaat gattgtctgc
       61 accaatttaa gtatgtcttt ttcactgcgg aggtaggcga atggattgta tttcatagac
      121 tttttaaagt taatggtatt aaggattttt atctcatatc cgttatcttc aagcattttg
      181 ccacactcaa ggactatcgt tccctttgga tctgttacgc aatagctact gtgcatttgc
      241 attaggttcg gcttgacata aaaccttgtc ttgccacttc cagatcctcc tatgacaagt
      301 acatttttat ttcttgcata cttgggattt ttcggtctac cattcatagt taatcgttct
      361 gtttgcgtta gcaagatatt gttttgaaac ttttcatcaa tgtacggctc aatatctttt
      421 ctagttcccc atcttgccga gccatactct tttccctgcc taaacttttt cgcatttttc
      481 ccttttgtat aggcaatgaa tttgattaaa gtagctactc ctacgcctat tagaatatca
      541 gttggatgaa aacttggaag aaagctcatg gtgttaagtt ccaatatacc ttgaaatatt
      601 ttgtctatta catcgccacc agtatatgct cttacatgat gagaaaagat attgccaaca
      661 tagaaaaatg caagataggg aatgttctgc tttagaaact ttgccttatc ttgcacctta
      721 aataagcctt tgatgtcttt tagtatctta tctatcatag gctttgctcc ttttgtttat
      781 ttttgatttt ctcttttgaa atagagtttt tagccatctc tttgaacttc tcaatattct
      841 tgtgaataga ttctttcctt tctgctttct tttctgattt tgaaagagcg tgcttaaaag
      901 ctttatccat aactttcata tctttggctt gaaagaatac agagtttttt cctgtctctt
      961 tatttttcat cactgaaaat ttaacaccgt atctattcag ctctttttta agttctttaa
     1021 gctcagcttc ttccactggg atttcttcaa gctgtccctt tttaaccata tcttttagct
     1081 ttacttcatt tccgttgaca ttgaccagtt tttcaagtcc tccgaatttc tctgcttctt
     1141 tcatcaattt ttttaataag tttaatagac cttttccagt aactttacca gcatttatct
     1201 ccatatttaa ggtctttctt gctatttctt cattgatcac atcaatatcc tcctctcata
     1261 tcatagctta caagagccga ataataggca tctattccac ttggtgcatt ataagcggcg
     1321 gtcagtacaa aagctcttat atttctaatc ttatattcat tttctcttaa tactcctact
     1381 aagtactcta aatgtcctga attaagtttc ctaaatcttt cctttactac ttgtacagat
     1441 atctttgttt ggttgatagt aataaaagat tcatcatcta ataccattac atctgccagt
     1501 atctttaata tttcatcaaa ctcttcagcc acactcttat tcccaatgct catatgttca
     1561 tagtatcctg tttggtgtcg caattcttct aaacaatttt gatatatatt tttatagctt
     1621 atatctatcc tccctccctt catattctct gaaaataatt gattattttc tttgatggaa
     1681 ggatggatgg aaatatatgc tgaattattt gtagtattat ttgttgtatt ctctggtaat
     1741 ggttggtgca aattatcctt ttgcattagt gcattttgaa cctgtgcatt agtgcaatct
     1801 gcattattgc attggctgat tttgccctta tccattggtg cattttgccc taatgcattg
     1861 ggcatagaat tttttaatgc ttctgtttgt attttttgtt tttttaaatc catatccata
     1921 tataattctt caagtttatc attattaatt gtataccatt ttgttttatc tcttggatcc
     1981 ttattgtaat ttccaactaa aagataacct gctttttcta actttgaaaa agttcttttt
     2041 actgtatcaa agctcatata gtcaaagtca ttttcttgcc atgctcgaat tgaattatat
     2101 gtccagtatt tcccatcatg gtaattcttt cccgattttt tatttatttc tatccaataa
     2161 ttgatctgct gtagtacaag cgcttcgttt aatcctaatt ctcttgcaag agttttattc
     2221 gcgactatag gttgttcatc aaataaatac ataccatcaa acactccttt cttttttcaa
     2281 ataaaaagac gatagttttt ctatcgcctt tgataaccca tttatgaaat ttttaacttt
     2341 actgtctgta atttataata ctattttctt ccattttcta attttgttcc tgaaagtttt
     2401 aaaaggagct acagtattca catgaataaa cttataaact tcccacactg ctgttttagt
     2461 cgcatcatca gcccattttc tcatatgtgg tttaaataat tcttcatcac ttaatgaatc
     2521 aatcattaca tatatagaat taatattttc atttaattta gattttaact cttgcaatga
     2581 taaataagcg taggtatctg tgaaccattg atataattca ccaagttgat tccatttgaa
     2641 ttcatccgat ggtgtcttta cttgaagccc atttctttca tcttcttccc atttaagaac
     2701 taaagttgtc catcccacct gataggcaag attttctacc ggcgttctgt caacttcatc
     2761 aattctttta tcttttaagc tttctggaat attatcaaat tctgcaatat acttctcaaa
     2821 tgttttattt atttcagttt tgagttcttc tttattttcg tatactcgca taaaattacc
     2881 tccacaactt ctgatttatc aattctctga tttaaactga cattattttc tcgtttatac
     2941 cttgcaataa ttctataatt gacgctccaa ccatcggtat cccataagga ctaagtaaaa
     3001 atcctataat taaggcttct ataccaatgg taacctcttt ttgtaaaaaa gatgctattg
     3061 ctccaaatat acaaaacatc atcagcaagt acagtattac tgttcctatg ccaagtaaaa
     3121 atgaaagaac tgcagtgagg atacttaaca acaagctaat tggaaataag ataattttta
     3181 atatccatct cataaatacc ctccatttct actaaatcat tttaaaatgt cttaaagcat
     3241 ccatgatagc ttcttctttt tcaggcgtac actgtgggat agcctgatta tcttttttag
     3301 atttattata atgttctctc atttcaatcc cacatttctt tttaatttgt gcaatataaa
     3361 gtgtagaaac ttttagtcca aatttttcta atacatactc cttgatttga gcgtatgttg
     3421 ctttactctc tgcacttgtc aaatcaagct catccagctt aatttcaaca tctatatgct
     3481 tatcgacatc aagtttggac aataacgcta ccgtctccac atgtgtagaa tgagggaaca
     3541 tatctacagg ttgtgcctca acacatttaa atccgtgaac atttagatag tctaaatccc
     3601 ttgctaaagt agaaggatta caagaaacat agacaattct ttccggattc attgaaacaa
     3661 tagtctctaa taccttttcg tcacatccct ttctaggtgg gtctacaacg actacattgg
     3721 cagtcttacc ctctctatac atcttaggta caatttcctc tgcctttcca acataaaatt
     3781 cagcattatg tatattgttt aatttagcat ttattttagc atcttttatg gcatcatcta
     3841 taatttctat tccataaacc tttttagcct tttgtgccaa aaataaagat attgtaccta
     3901 tcccacagta aatatcaaaa acagtatcag tatcatttaa atttgcatat tcaagagcct
     3961 tatcatacaa tactttagtt tggacagggt ttacttggaa aaatgataat ggtgaaatct
     4021 caaacactaa gtcacctata taatcgttta tttttccatc tccatatata actatatttt
     4081 ctcttcctag aatagcattc gtatcttttt gatttacatt tacaaccaaa gtcttaaatc
     4141 caggtatatt ttccttaagc actgaagcta attctttaag atatggaagt ttgtttccat
     4201 ttgctactaa tacaaccatt acttctttag ttgtaaaacc tatttttgtt actaaatgcc
     4261 taatcaaccc cgtgtgagtc ttttcatcat atatacttac cttataggcc cttatatatg
     4321 tttttattat tttaacaatt ttatcattta tctcatgttg tattacgcat ttttctgtcg
     4381 atattacatc atgagtcttc tttttataga agccaataat tggaatacca ttattctttt
     4441 gtattggaaa ttgtgcttta tttctatatc tatatggatt atccattcct atagtgtcat
     4501 gaacttctac atcttctaac ttacctattc tcgaaagtac ttgtttaact tcatttgttt
     4561 tcatttcaag ttgtttatta taatctaagt cttgtatctg acaccctcca caatccctaa
     4621 gattgtcact acacactctt ttcaccctga atggagactt ttctattatc tcaacaatat
     4681 ctcccacagc ataatttttc tttactttat taatcctaac tttaacttta tcatgtatta
     4741 atccgccctc tacaaaaact gtaataccat tgtactttcc tactcctact ccgccttgac
     4801 caatgtctac tatatctaca atatacatct cgtttttcga aagcataaat caccctccaa
     4861 tcaatctatt atatttaaat ctttacaaac ttttttcttt aaatttatat taaaatattg
     4921 ctattaatta aactatattt tttactaagc tacaatattt tattttacca aaaaaaaagg
     4981 agcttataaa gccccttagt aaataaattt attatttttc ttataaaact ctagttgaac
     5041 ctctatatac cacacctctt gatgcatcca cagttacaac ttctccatct tttactagat
     5101 ttgttatatc agttgcagac acaataactg gtatatctaa atttatacct acaatagctg
     5161 tatgtgatgt cattccacca ttctcagtta ctacagctcc tgctttttct atataattgt
     5221 tcatttcagc atcagtagca gtagaaacaa gtatgtcgcc ttcattaaag tctacacaag
     5281 catttccatt ctttattata cgaactttac cttctactgt ttgagtacct acacctatac
     5341 cttgcacgat ttcttcgctt attacatgaa cctttattaa attagtagtt ccacttactc
     5401 ctactggtac tccagcagtt ataactacta attccccatt atctatataa tcagcttgtc
     5461 tagctgcctc aattgccttc tctataactt catctgtatt tcctgcaaca gaagacttaa
     5521 ctggatatac tccccatgta agagctaatt tattcatagt cttttcatta tttgtagtag
     5581 ctattattgg agattttggt ctaaatttag ataccattct agcagtatat cctgaagaag
     5641 tagatgttat tatagctgat gcatttaaat ctactgctgt tgtacaagtt gcatggctta
     5701 ttgcatctgt tacagtaaca ttgttagtac cattttcctt tagtaatcta tcataatcta
     5761 aagtctcttc tgttcttttt gctattgtag ccatcatttt tactgcctct acaggatatt
     5821 ttccagcagc agtttctcca gataacatta tcgcatctgt tccatcatat atagcattgg
     5881 caacgtctgt aacttctgct cttgttggtc ttggatttct tatcatagaa tcaagcattt
     5941 gagtggcagt aacaactggc tttgctaatt cattacattt ttttatcatc attttttgaa
     6001 ctattggcat ctcttcagtt ggtatctcaa cacctaagtc acctctagcc accattatac
     6061 catcagaaac ttttaatatt tcatctaggt tctctacacc ttcttggttt tctattttag
     6121 atattatttg tatatcagtt gcattattgt tctctaatac ttctcttatt gctagtacat
     6181 cagatgcctt tcttacaaaa gaagcagcta tataatctat tccttgactt attccaaact
     6241 ctatatcact tatatcttta ggagttattg ctggtaaatt tatcttaaca ccaggtacat
     6301 ttactccttt atgattttta actattcctg aattttcaac aacacaaact atatcttctc
     6361 catttatttc ttttactctt aagccaacta aaccatcatc tattagtata gaatctcctg
     6421 atttaacgtc ttcagcaaga cctttatagc ttactgtaca catttcttta gtccccataa
     6481 tatctttcat agttatagtg aacttttgcc cttcttctaa aaatacctct gggtcttcaa
     6541 agttacctgt tctaatttct ggacctttag tatctaataa tatagcaact ggcttattta
     6601 atttttctct aactttcttt gccatatcaa ttctttcttt atgttcttca tgcgaaccgt
     6661 gagaaaagtt aaatctacac acatttagac cattttgcat aagttgagtt aaaacttcct
     6721 cactttgtga tgctggacct agtgtacaaa caatttttgt cttctttaca ttatttaaca
     6781 tatttgctcc tcctgagata ttattccaca gatttatttt taatactaaa acttatatag
     6841 ataatatttt tgccatctca taagcttctt tatcaaatac tttcttttga gctaaagctt
     6901 cacttatttc taaatcaatt attttgtttt cttttattcc tacaactcta gctgattttc
     6961 catctaataa taattctact gctcttactc caagtctact tgctagtatt ctatcagata
     7021 cagttgggct tcctcctctt tggacatgcc ccaatacagt gactcttaaa tctgctcctg
     7081 actctttttt aagttccttt tctaaatcac tagcacttcc gactccttct gctaaaacga
     7141 ttatactatg tctcttacct cttttttgag tagtctttaa tcttagagca acttcatcta
     7201 ctgtaatttc tacttctggt actattatag tttccgctcc tcctgcaaga cctgcatata
     7261 aggctaaatc tccacagtgt cttcccataa cttctactat gttaactctt tcatgagatg
     7321 atgatgtatc tcttatctta cctatagcat ctataatagt attcattgca gtatcaaatc
     7381 ctatagtata atctgtatat gctaaatcgt tatctatagt tcctggtatg cctatagctg
     7441 ggaatcctaa gtcactaagt ttttgggctc ctgcaaatga accatctcca ccaattacaa
     7501 ctaaacaatc aattttatac tttttaagaa tttttactgc ttttaatcta ccttcttctg
     7561 ttttaaattc ttcacatctg gaagatttta atatagttcc tcccctgtgt ataatatctc
     7621 caacagaaga taagttcatt tcagttaaat cttcttctag taatccctta tatcctctat
     7681 tgattccata tactttgcat ccataatata ttgctgatct tacaaccgct ctaatcgcag
     7741 cattcattcc tggagcatct cctccgcttg ttagtaatcc tatagttttc attttttacc
     7801 tccttggatt ttatgtcaat tttttattat aatcattgtt attgtattct aatggacttt
     7861 ttttgtccct atatcacttt ttaatcccat caagactaaa aaaattaaat gtccttaaat
     7921 gtccattttg tgatattata tcacaaaacg gacaatattt ttcatattat tataatatat
     7981 ttagattttt atataaaaaa tcaagctttt acttttatgt tatctttagg aagtaactct
     8041 tctaagttat ttataaattc atcacatata caagtcaatg ccccggtcat tttatatgct
     8101 ttacgtttac catttatatt ttcatccata gggtataagt atatactgtc attacctgga
     8161 tattgtttgg ctatttctac aatattatta gttgtatcag tatcagacat actatctatt
     8221 ttcaaataca attttttacc actttctggc ttaatatttt ctacatttct agttcttcct
     8281 gaattgtagt ttctatctgc aaagtcagta tcatcattta tatcttttat ctctctagct
     8341 ataagttttg cattttcgcc ttcttttata cttaatgttc cttttacata tattatatta
     8401 tcttcattca aaatgacatt atacttttgt aataattgag gaaaaactat tatttctata
     8461 gcaccataca aatcttctaa ttcaataaat gccataattt catttcgttt tgttgtttta
     8521 atagttttag ttacaatcat tccacccatt ataacatctg tttcattcat ttgtaggtat
     8581 gactcttctt cctcttttaa tgaatttaat tttccattat ccatagatgt tttttcttgt
     8641 agttcttttt caaattgtga taaaggatgt ccacttacat acattcccaa gacttctttt
     8701 tcaaggttaa gtctctctct ttcttcatac tcttgccttt taggtaaact gtatatttgt
     8761 tgaaaatcac tatcttcctc actatctcca aaagcatcaa ataaagaaat ttgaccttga
     8821 acatttttct ttctatccat agatacactt tctaataaac tttcataacc agccatcaaa
     8881 ctagctctat tttcacttat attatcaaaa gctccacatt ttattagact ttctattact
     8941 ctcttatttg tatctttttg gtctaatctt ttgactaaat ctactaaatc tacaaataat
     9001 ccattagatt ctctttcagc gattatattg tttattatat ttacgccaac attttttacg
     9061 gctgctagac caaatcttat attgtcgcct tcaactgaaa actttgaaaa acttttgttt
     9121 atatctggag gtaatacatc tatttctagt gctttacatt ctcttatata ctcaactacc
     9181 ttatcagtat ttcccattac actggttatc aatgctgcca taaattcaac tggataatat
     9241 gtttttagat aagctgtctc atatgctaaa accccatatg cagctgcatg tgatttatta
     9301 aatgcatatc tagcgaagtc tatcatatca tcaaatattt tattagctat ttcctcttct
     9361 acaccatttc tgatacaccc tgcaatttct atattaccat cttcatcaaa tttaccatga
     9421 ataaaatatt gtctttcttc ttccatcaca tccatctttt tcttactcat ggctcttcta
     9481 actaggtcac ttcgtccgta actataacca cctaaatctc taacgacctg cataacctgc
     9541 tcttgatata ccaaacaacc atatgtaact tccattatag gctttaattt ttcatgtaga
     9601 tatgttacat cttttgggtt gcttttattt tttatatatg caggtataga atccattgga
     9661 cctggtctaa atagggatat tcccgctaca atatcttcaa aattgtctgg ttttagctgt
     9721 ttcataaaac ttctcatgcc agcactctcc aattgaaaca cccctagtgt atttcctgat
     9781 gaaagcattt catatacttt cgggtcgtca taatccatct ttgaaaagtc tattttttct
     9841 gtgtagtttt ttataactct atttttttct attaaatcaa gagtatctct tataactgta
     9901 agagttctta gcccaagaaa atccatcttt aaaagcccaa gttcttcaag tgttgtcata
     9961 gtaaactgtg ttgtgattgc atcttgatgt ttgtacaaag gtacatattc atctacggga
    10021 ttttttgata taacaactcc tgctgcatga gtagaagcat gtcttagcat tccctctatc
    10081 tgttttgata tatttattat ttcttttgtt tccgggtctt ggtcatacaa ttctttaaga
    10141 ttaggatttg tatctagggc cttatctatt gtcattccta aagcaaatgg tatttccttg
    10201 gctaccttgt caactttatt gtagcctata tccaataccc ttccaacatc tcttattgca
    10261 gcttttgcac ccattgttcc aaaagttatt atctgggcta catggtcatc accatatttt
    10321 ctctttacat aatctataac ttcttctctt ctctcataac aaaaatctat atctatatct
    10381 ggcatggata tacgttctgg atttaaaaaa cgctcaaata atagagagta ctttattggg
    10441 tctatatcag ttattttaag tgtatatgct actatcgaac cagccgcact acctctacct
    10501 ggtcctacta taatattatt ttctttagaa aaatttataa aatcccaaac aattaaaaaa
    10561 tactctacat aacccatttt ttcaattaca tctaattcat aatttaatct ctctagtatc
    10621 tcattgctag gattatcata tctctctttt aatccattaa aacacaactc ccttaaataa
    10681 gtttctggtg tatatccttc tggaacatca tacttaggaa gatgtatagt attaaaatca
    10741 aactccacat tacacatatc agctattttc acagtattgt caatagcctc taatgcatat
    10801 ggaaataatt cttccatttc ttctcttgat tttaaataaa actcatcact accaaatctc
    10861 attctatttg ggtcatttaa tgtttttccc atttgaatac acataagtac atcatgtatt
    10921 ttcgaatctt ctttatttac atagtgaaca tcattagtag caactagtgg tataccagtc
    10981 tcttttgata attttactaa accagagttt acttcttttt gctcaggtaa attgtgatct
    11041 tgaatctcca aaaagaaatt ttcttctcca aatatgtctc tgtagtcaag agcaaattgt
    11101 tttgcttttt cataatttct attcattaaa gcacgtgcta catctcctgc aaggcatgca
    11161 gaaagtgcta taatcccttt gttatgtttt ttaagttctt ccatgtcaac tctaggctta
    11221 tagtaaaaac cttctacgta tgaagttgaa actattttta ttaaattttt atatccttcc
    11281 atattcttag ctaacagaac taaatgtcct tgatatttgt catagtttgg gtctttatct
    11341 ctcaatccac gtgcagctgt atagacttcg caccctataa ttggctttat tccttctttt
    11401 atagctgttt tgtagaaatc tataacacca aacatacaac catggtcagt tatagctatt
    11461 gagctcatgt ttagttcctt agcccttttt ataagttttt tcaccctcga aaacccatca
    11521 agtaaactat actcagtatg tacatgaaga tgagcaaaat ctttgttcat taaatcacct
    11581 cctgctttat aattttaatt ttaccacaaa tatatgtact aaaacaaaaa cagagacttt
    11641 tatctcaaaa taggaattaa cttcaacgta taccattata tgttataaat taatgcttat
    11701 tctgagattg tcccctcaat ttattgctat gatttttttt caaatctgtt gcaatttctt
    11761 ctatttttct aagtctatga ttgactccag attttcctat tggtggttct aacatctctc
    11821 caagttcttt gagagtcata tcctcatact cgattctaat cttagctatc tcttgtaaat
    11881 tttctggcaa actgctaatt cctatagtct cttgtatgag cttaatattt tctacttgtc
    11941 ttactgctgc atttactgtt ttagaaaggt tagctgtctc acaatttact atcctgttta
    12001 cattatttct catttctttt actattttag tattttgaag acttaaaaga gcgtggtgtc
    12061 ctcctataat actcaacaaa tctgatattt gttcactctc tttgatataa acaacgtgat
    12121 tattttttct agccacaatt ttactattaa aacctaaaga gtttataagt tcttttagag
    12181 aatctgcaaa ctcctcatta ttagttacaa attccatatg atagttcttt tctgggtcgc
    12241 ttatagaacc tccaccaaga aaagctcctc ttatgaaagc tctcttacat ccttcatgct
    12301 taattaagtt ctctgaaatt ttgtttatag taaaaaatcc ttctttatct tcaagtatac
    12361 ctaacttttt taataacatt tctgaaccca tttcgcttgt taccattaat acataactgt
    12421 tatttctctt tagcatttga ttcttattta ctgagattgt agtattgata ttaaaattct
    12481 tttttaataa tttaaatact ttacgggcta ttgaatttaa ctctgttgtt atctttagat
    12541 ttagcttctt atatccaaca atttgtatac ttccccctga tttaactaga gctgacaatt
    12601 cagctatatt acaacattca ttcccagata taactcttgc tagttcattt ttggtttcag
    12661 ttgaaaaaga catatctatc acctattaac taatttttct ttaacctttt ttttatttct
    12721 tgtaaggcaa cctttattat ctccttttca tcatcatacc tagctaagtc tactactcta
    12781 tctaggtgga taaatttagc atcaataaag ccttcctctt tttgtggaat agtatccata
    12841 ttctttgctt gcatcaaata ccaaaaaact gttttatgaa ctgctctatt ttcatcccag
    12901 ttttctttga atgtatagtg tatttcacct aaatatttca atatatctgc ttttactcca
    12961 gtttcttcac ttacttcacg taatgctgcc tcttggttat tttccccttc ttctactttt
    13021 cccttgggta acacccaatc tccattgaac ttccttagta aaagaatcgt attgccaaac
    13081 aggactacac caccagcact aacctcttct ctcatcgatg ttcactcctt aaaactaaca
    13141 taatgataag gatttctaca caatttttta aaatcctttt ttactaactt ttgttgtaat
    13201 tatgatttag ggctaactca ataactatgt tagatatata ctttgcatca tgtcttatat
    13261 aattattttt tatttcaatt aaattcttct ctacagtttt tatacccatc tcttttaatt
    13321 tatctttttg ctttttatct aacaagactt gctctgctcc atcttgttta tataagtcaa
    13381 gcatttcttc tggcaatatc tcattatttg cgattacata atctattaaa ttctcatcag
    13441 tgtgttttac tatagcatta acatgctcta atacattgta cccttctgtc tcacctggtt
    13501 gagtcattat atttgctata tatacttttg gagctacaga cgatttaata gcgtctacaa
    13561 tcccctctac aagtaaattg ggtattatac ttgtatataa acttccagga cccataatta
    13621 taatgtcagc atcataaata gatgcaataa catcctttaa tggttttaca tcttttggat
    13681 ttaaaaaaat tttatcaata gagctttttt gaatttttga ctcttcaggt atactagatt
    13741 ctccatttat tatattgcca ttttctaatt tggcaactaa atttacatct tccaaagtta
    13801 ctggtaaaac tcttcctgtt atagcaaaaa tttcacttaa tttatataca gctttttcaa
    13861 agtttccata caacccattc atagcagcca aaaacaaatt tccaaaactc tgacctttta
    13921 aaagcccttc tgtaaaccta tattgcataa cttcattcat tgttggctct atatttgcaa
    13981 gtgctaataa acagtttctt atgtctcctg gtgggagcat tcctaagtct tctctcaata
    14041 cacctgaacc tccaccatca tcagcaacag ttacaattgc agttatattt tgcgtagtgt
    14101 gtttaaggcc tcttaagaat accgattgac cagtacctcc acctatcaca accacatttg
    14161 gttctctatt ttcaacaata gacctttgaa atagttttac tttttcattt tttgcttttt
    14221 tatatataaa taacgataca attaatgcaa tccaacctaa aattcctaca ataataagta
    14281 atttagccat gtttgcctcc attatcgcaa catagagtct ctatgtttct ttacaactct
    14341 atatccctta ttagataaat cctccgctat aagatttgtt atagtaactg acctatgtct
    14401 tccacctgtg catccaacac caattactag atgttgtttt ccttcctcta tatattgagg
    14461 tactaaaaaa tgaatcatat ctaaaagttt cacataaaat tcttcactga ttttagaatt
    14521 cataacataa tctctaactt ctttatcatc accagtttta gctcttaact cttcaacata
    14581 atagggattt ggaagaaatc ttacatcaaa tactaaatct gcatcagcaa gtataccatg
    14641 tttaaatcca aaagatacta cagaaatagt taggtttgga ttatcttcac ctgaagaata
    14701 tattttcttt atttcttcct taaggtcttt aggtttcatg ttagttgtat caattataca
    14761 tgtagataac tcctttaaag gttccattat ctttctttcc atttttatac cttctggaat
    14821 ctgcatatct tttgccaatg gatgatttct tcttgtcatt ttatatctct ttaacaatac
    14881 atcatcatta caatccaaat ataccatttc atattcataa ttttcttttt ctaaataatt
    14941 taagctttca tgaagcgctt caaaaaactt tctccctctt atatctatcc ctagagcaac
    15001 tttatcaata cttgaatttg gttgataaca taattctgca aatttagtta tcaaagcagg
    15061 aggtagatta tctacacaat aaaatcccat atcctctaaa gctctcattg tctcactttt
    15121 tccagatcct gaaagacctg taactataac aaatttcatt gctaactcct cccttttatc
    15181 ttatgtttat tatattataa tgttttctac taacgatata tccagattag agtcagatat
    15241 agtcttcata gctagttcaa aatcaccaac tctttctgga caatgtgcat ctgagcctat
    15301 tataaattta ttttctagcc cttttatttt atttaattga tttacattca aaaaagaatg
    15361 gctactattt atctcaagtc tagtatttgt cttttttgct gtctttgcta cttcttctat
    15421 atacacatcg cctttatctc ctggatgagt aattataaaa atatcattat tacttatcgc
    15481 atttattaca gcttttgtat tatattcttt tgctttttca gttttaaaaa tatagttatt
    15541 acaatgattt aataagcttc ttaatgatgt tggagtagaa ccaaaatgat atccagccat
    15601 aatataatca aaatctctaa taaatttatc atccatatct atatttcctt tatcatctaa
    15661 tatgttacac tccataccta aaagtatatt tatatcagtg tacttatcat ttaaataatc
    15721 tacttcttct ctcattttga gaatatcttt tttctttaca ccatatgcaa tatgtttata
    15781 actatggtca gatattccta ttgtttttat tcctttagaa atggctacct ttacattatc
    15841 ctcaatagtc cctttgccat gactatataa tgtatgtgta tgataatcag ccagtatttt
    15901 catttgttaa tcctctccaa gtattttgac ttcttcttcc aacataaccc caaacttggc
    15961 atatacagca ctttttataa catatattaa atccaaaata tctttagcac ttgcttctcc
    16021 ttgattgact acaaatccac aatgcttctc agatacttgt gctcctctta aagtaagacc
    16081 tctcaatcca gtttcttcta ttaatttacc tgcaaaatat cctgttggtc tcttaaatgt
    16141 acttcctgca ctagcaaaat ttaatggctg tttagttatt cttctcgtcg ctaaatcatc
    16201 cattaaactt tttatttcat cataatttcc ttcttgtaat tctaattctg ctgataaagc
    16261 tatatatccg tttttcgata ttatactttt tctataccca aattccatct gttcatttga
    16321 taattcaaat atattgcctt ccatatccat cagtcttact gacttcacta tgtccttcat
    16381 ttcaccacca tatgctccag cattcatggc taatgctcct cccaatgtgc caggtattcc
    16441 tgatgcaaac tcaaaccctt ttaattcttg cttttggaga gctttcccta aaactgataa
    16501 taaagctcct gactgagcag tcatcctagt atcatttatc tcataagaat tgaaattatc
    16561 agctaattct attaccactc ctcttattcc accatcttta attaaaatgt ttgaaccatt
    16621 tccaattatt aaatacggaa tagattcttt ttttaccaac ttaagtacat tttttaattg
    16681 ttcttcagtt ctaggtctaa ctaatatatc tgctggtcct cctaccctaa atgaaatatg
    16741 ttttttcata ggttcatcga cttttatatc ctctttactt aatatattta ataaatttat
    16801 atatatatct tgattattca ttgtatttcc tcccaaatta tactgaactt tagctgtcat
    16861 tattatttaa attacattag tatatagtat taactatatt caataatata tgattttgct
    16921 tatcatatag attttatatt ttaagcttct taattacaaa ctatattcaa taaatatata
    16981 ataaagtaaa aaaaaaaaaa taacaacata taaaagaata taaataattt aaaaaaagca
    17041 tcaatatcac tgatatcaat gctttaaaag gcaatttaat tcgtattatt tatctaacta
    17101 tttttgacat agcaaagata ataaatccct ccaactacta tggaacctcc aacgatattt
    17161 ccaagtgtta caaataccaa attagttata aattgaacca tagttatatt tgctcctaat
    17221 gccattccca ttggtataaa aaacatgttt gcaacactat gttggaatcc acataataca
    17281 aatagcatta ttactgtcca acatgaagcc aattttgaca ttatatcttg agatgctgta
    17341 gccatccata cagctaaaac gactagaata ttacaaagta ttgcttttaa aaacattgat
    17401 gctatagttg aattaacctt agcttctgcc acagctatag cttttgtagc tgcatctcct
    17461 gtcaatgtag aagaataaaa cacaagtgca actagcaaaa ttgaacctac taaatttgca
    17521 aaataaacca gtccccagtt tcttaacatt tttcctaatg ttattttttt gtccataagt
    17581 gcaatagcca ttaatgtgtt tccagtgaat aattctgctc ctgccactac tacaagcata
    17641 agacctactg gaaagaccat agcacttaaa aagctagcta cccctgggtc tatcttgcca
    17701 aaagtttgac taactatcat actccccaat gccccaaaac ctataaatgc tcctccaaat
    17761 aaacctaata gaattgcgtt ttgtgtcgaa atatttgctt ttttaatgcc tgcacttata
    17821 gttgcttgtg cagtttcccc aggtgtcaag aatcctttac tcataaatcc ttccccctta
    17881 aaaattatac tttcccttgt ctttttatgg caataattat ataataacaa tatgatatat
    17941 aataaatttt attaacataa aaaatatact atatacttat atatacttgt ctcatataat
    18001 tatactattt attatataac aactttgtta atttcgaaat aatttatatt gaatttgaaa
    18061 aatttacctt ttgattattt attttacttt ttaattattg aggtattata tataatagat
    18121 atatgtttgt gttattatat ataattactt attttaataa atatttgaag gagggaattt
    18181 tatgtttgat atatcatttt tcgaaatgtc aatatatgaa atagcagtta ctacaatata
    18241 tataattaat ttcatggtta tactaaacct tatctttaga gaaaaaagaa acataaatac
    18301 aactttaaca tggcttctta tattagtatt gattcctgct cttggattca tactttatat
    18361 agcttttggc agaaatattt caaaaaacaa tatgtttaga ttgaaagaaa aggatgataa
    18421 gataatcaaa agtaatatac tagatactca ggttaaactc caatctacat ctgaaattga
    18481 ttcagatata catcaacata aggatatgat ttatgcattg gctaattcaa ataatgctca
    18541 ttataccaat aataacgatg tgtggattta tgctgaatct agtcaatttt ttaacagtct
    18601 tcttgaagaa cttaaaaaag ctaaaaaata tataaacata caattttaca ttttcaaaga
    18661 tgacaaaatc ggaactgaaa taatagacat tcttatagac aaagctaaag aaggtgttga
    18721 agtaagactt ttatttgatg cagttggtgg tagaacacta aaaaatagta cactttccag
    18781 acttaaagaa agtggtgtta aagttggaag cttcttccca tcattcttga aaattgtaaa
    18841 ctttaactta aactatagaa atcaccgaaa aattgttgtc attgatggta aggtaggatt
    18901 tgtaggtgga tataatgttg gtgatgaata tttaggtaga aatccaaaat ttggtctatg
    18961 gagagataca catactaagc ttactggtga ttgcgtaatt gacctaaata tgagattcat
    19021 ccttgattgg agatatacaa ctaaagaaga tttagattta gaaaagtact ttatagaaga
    19081 agatacaaat tctaatcatc cttctgaaaa tattgggatt cagatagtat caagtggtcc
    19141 agatatatca gaacttgatg agattaaata tggttacctt aaaatgattc agaaagctag
    19201 aaagtatata tacatacaga gtccttattt aatacttgac tcaactttta tagatacttt
    19261 aaaaatagct tgtttatctg gtgttgatgt gagagtgatg attccttcta aacctgacca
    19321 tccctttgta tactgggcat catattcata tgctggagaa cttttaaagt ttggagctaa
    19381 aatctacact tatggtcaaa atgcattttt acatgctaag acaatagtta tagatgactc
    19441 tatatgctct ataggaacag ctaatatgga tatcagaagt tttgagctta atttcgaagt
    19501 taatgcattt atgtactctt caagaaaagc attggaacaa agaattatat ttgaaaatga
    19561 tattttagat tctaaggaaa taacattaga tatatataat tctaggtcta cttatataaa
    19621 aatcaaggaa tcaatttcaa gactattatc agcagtttta taaatctttt attttataaa
    19681 aattttacat tttggtttat tttttaaagt tttttatatg tattattttt tttttattga
    19741 atttagctca ttttttttat tttttttaac tattctgaat tattttatat tataatagac
    19801 tagtatagtt tttattttta ataggtaact tttttgcatt gtttttataa ataaagaaat
    19861 tgttgtatat tattctttct ttattgtttt ggttttgttc acccacataa tgttggggtc
    19921 aactcatggt taattatttt atgaaaaata ataactttaa aaagaaaagg gggatttgtt
    19981 atgtgcgatt ttatttcaca caacaagcaa ttatttgacg aactagatat atttattgac
    20041 tctcttgcaa caaaggaagg tgcgttaata caagttctac atgaagccca aggtatattt
    20101 ggatatcttc caaaagaagt tcaacttcat gttgctagaa aacttggagt agctcctgca
    20161 aaggtatatg gggttgttac attctattct tattttacta cagaacctgt aggtaagtat
    20221 aaaatcagtg tctgtctagg aactgtatgt tttgtaaaag gtgctgacaa aatcttaagt
    20281 gcttttgaaa aacagcttgg cataaaagtt ggagaaacta ctagtgattt taaattttct
    20341 ttagaaggtt taagatgttt gggggcatgt ggtttagctc cagttgttac tgtaaatggt
    20401 aaagtttatg gtaaagtgaa acctgaccaa gtaagcgaaa tattagatac ttatagagaa
    20461 ttagaattga attgttaaga ggggtgaata aataatgcgt aaagtaaatt catttgatga
    20521 attaaaagtt ttagctgatg agctgaaacc taatcttagc ttaagaaaaa attattctaa
    20581 ggaaaatgta ttaagaagag aattacttgt ttgttgtgat actggatgta catcttcaaa
    20641 cagtctagaa atagttagtg aattagaaaa tgaaataaag aaatcaggaa tccaagataa
    20701 agttagtgtt cgtttgacag gttgttttgg tttctgtgct caaggtccta ttgtaaaagt
    20761 ttatcctgat aacgttttct acgtaaaagt tgagccatct gatgctgaaa agatagttca
    20821 aagccactta attagaaata cagttgtcga ggaattatta tatgaggaag aatctttaag
    20881 taaaaaagtt gaagaacaag aagaaatgtc tttctacaaa aaacagttac gtatagcttt
    20941 aaaaaattgt ggtcttatag acccagatag tatagaagaa tatattgcca atgatggtta
    21001 tttagctcta ggcaaatgtt taacttctct tactcctcaa gaagttattg cagaggtaaa
    21061 aacttctggc cttcgtggta gaggtggtgc aggtttccct actggctcta aatgggaagc
    21121 tgcttcaaaa aatccagctg gtccaacaga taaaaagttt gttgtatgta atgctgatga
    21181 aggtgaccca ggtgcattta tggatagatc tgtacttgaa ggtgaccctc atagtgtact
    21241 agaagctatg gcaatatgtg gatacgctat aggttctgat acaggataca tatacataag
    21301 agcagaatat ccaaaatcta tagaaagatt aaaagtagcc atagctcaag ctgaaaaata
    21361 cggtttactt ggcgaaaata tcttaggcac tggatttaac tttaaattag aattaaaata
    21421 tggtgcaggt gctttcgttt gtggtgaagg tacagcgcta atgcattcaa ttgaaggtag
    21481 acgtggtgaa cctagaatga aaacttatag ttcttctaag agtggtctat ggaaatctcc
    21541 tacttgctta aataacgttg agacttttgc taacatacct gcaattatac ttaagggtgg
    21601 agattggttt gccaacttag gtactgaaga ttctagtggt actaaagtct ttgctcttgg
    21661 tggaaaggta gaaaatgtag gacttgttga agttccaatg ggtactactt taagagatat
    21721 tgtatttgaa attggtgggg gaatccctga aggtaagaaa tttaaggctg ttcaaacagg
    21781 tggaccatct ggtggatgta taccaactga acatttagac actcctatag actttggttc
    21841 attaagttct atcggttcaa tgatgggctc tggtggtatg cttgttcttg atgaatctga
    21901 ctgtatggta gatatagcca agttcttcct tgagtttact gttgaagaat cttgtggtaa
    21961 atgtacacct tgtcgtatag gtactacaag attattagaa atattaacta aaattacaga
    22021 aggtaatggt actctacaag atttagatga cctagaaaac cttgctgaaa ctatacaaac
    22081 tgcttcatta tgtggtcttg gtaaagctgc tccaaaccct gttttaagta ctcttcaata
    22141 ttttaaagat gagtatatag ctcatgttgt agataagaaa tgtcctgctg gtaaatgtca
    22201 gaacttactt tcttacttta taacagatga ctgtaagggt tgtacaaaat gttctagagt
    22261 gtgtcctgct ggttgtataa caggttctgt taaggaacaa catacaatag atacttctaa
    22321 gtgtctaaaa tgtggtgctt gtatagataa ttgtacattt aacgctataa tcaagaaata
    22381 acttatttgg aggaggaata acaatgagtt tagttaattt aactattaat ggcaaacacg
    22441 tttcagcacc tagtggaact tctatcttag atgctgcgaa attaataaat ataaaaatac
    22501 acaacctttg tcatttacat atgaatgaaa tagataagct tgacacttgt gcttcttgtc
    22561 gtgtttgtat ggttgagaca gagagaggat tagttccagc ttgtggaaca gttataaagg
    22621 aaggtatgaa agttcagact aatagtgcta aagcattaaa tgctcgtaga actattgttg
    22681 aattattgtt atcagaccat ccacaagatt gttttgtctg tgaaaaaaat ggagattgtg
    22741 aattacagac tatagctgct gatttaggag taagaaaaat aagatatcaa ggttctaaat
    22801 cttttgcagg taaagatact tctactaaat ctttagttaa agaccattct aagtgtatat
    22861 tatgtagaag atgcgagact gtatgtaatg acatacaaac agtaggagca ttatctggag
    22921 ttaatcgtgg atttaatact ttagttagta cattctttaa ctctgatatg gttgaaacag
    22981 agtgtacatt ctgtggtcaa tgtatatctg tctgtccaac tggagcatta acagaagtag
    23041 ataatgtacc taaactttgg gatgttttaa ataaaaaaga aaagactata gtagtgcaag
    23101 ttgctcctgc tgtaagagtt gctattggtg aagagtttgg attagaacca gggtcaatct
    23161 ctacaggaaa aatggtagct gctttaaaag cacttggatt tgaacatgta tttgatacaa
    23221 actttggtgc agattttact ataatggaag aagctactga atttatagaa agaatccaaa
    23281 aaggtgaaaa tcttcctata ttaacaagtt gttgtcctgc atgggtaaac ttcttagagc
    23341 acaattatcc agacaagtta aacttagcat ctagctgtaa gtctcctcaa ggtatgtttg
    23401 gttctatagc taaaaactac tatgcaccta aaatattagg aatcaatcct gaagaacttt
    23461 atgttgtatc tgtaatgcct tgtgtagcta aaaaatatga agcttcaaga gaagaattaa
    23521 gtgaatctgg aatactagat gttgaccttt ctataactac tagagagtta gctaagatga
    23581 taaaagaagc tgctatcgat ttacctaatc ttcaagacca agattttgat aatcctctag
    23641 gaaaatctac aggtgctgca tctatatttg gagcaagtgg tggagtttta gaagctgccc
    23701 tacgtacttc atatgagaag ataactaata agactttaga taatgtaaac ttcactaatg
    23761 ttagaggtct taaaggaatt agggaagcaa gtatagatgt tgatggaact acagttaatg
    23821 tgtgtattgt aaatacactt aaaaacgcta gaaagattat ggataaggtc agaagtggag
    23881 aatgtaaata ccatatcata gaagttatgg catgtcctgg tggatgtgtt ggaggtgctg
    23941 gtcaacctta tcaccatggt aatactgaaa tagttgatag acgtgcaaat gcgttatatg
    24001 aaatagatag aaataaggct attcgtaaat ctcatgagaa tcctgattta caagctattt
    24061 ataaagactt ctttggagaa ccaaatagtg atgtagctca taaatacctt catactcatt
    24121 actttgataa gagttgtgtc tatggagagt gtccacaaga atgtgcttgt gaagaagcta
    24181 agtagtcata acaaagtata aaatttattc ttaaaaaagg attgtcttaa aatactttta
    24241 cgtaatttaa gacaatcctt attaatttca caaattaaat tatatttcta aatagactta
    24301 ttctttaatt aacctatcta ttaattaaag aatacctgcc attctcataa gttgttttgc
    24361 atttgtagtt ttacatcttc catcttttat cttatagtca aaatgaattt tatcgtctac
    24421 atagtactct gagaaatgat agtttacaac ttcaatatct ccactacctg aaaggtcaca
    24481 tagctcaaag tcatgtgttg tcaccatact tataacccag ggttttgata atttctttac
    24541 tgcctcactt gctccaataa ttctatcagc agagttagtt cccttaaaaa tttcatctac
    24601 tagaaccaac attggcagtt cttttaaact atattgaatc attgatttta ttctaagaat
    24661 ctcagcatag aaagttgata ttccttgact tacatcatct tgtattctca tagaagtaaa
    24721 tatagccata caggtcgcat caaaactctt agcgcatact ggagcacctg catatgccag
    24781 cactaagttt acaccgatac ttcttaaaaa tgttgtcttt ccagacatat ttgaacctgt
    24841 gataatacaa gtctgagaat ttaattgtat cgaatttgct atgacacttt tttctgctat
    24901 taatgggtgg tatacctctt caactttcaa tcttggagta tcttcatatt ttattactgg
    24961 aaaacatgta ttttccttta catgagaaac aactgttaaa cttattagag cttcaaattc
    25021 tccaatagat tcaaaccaat ctctaatttg atttccatat atacctttcc atcgctccaa
    25081 agcttctgca caatgatagt tccacatcaa aacaccacag gcaattatat atagtatctg
    25141 attatacctt aggtttacag catttcctat tgaatttaat tgtttaacac ctcttgaaac
    25201 tccacttccc ttagaaagtt tatcttgtaa ttctttcaaa tatgcactct caaacgtctc
    25261 tttttctaaa acctcaaaca ttttttcata tacttgtata cttctactaa atgaaaataa
    25321 tggagcaaga gtttgcataa gtcttggata tccaaaacca ctaaacccta actggattat
    25381 aaaaagtaaa aaaacaggta aaacaggtaa aaatcctaac atacaaaata taaaagataa
    25441 gattgttgca gttggtaaac cccaagtaaa aatatgcatc cattttggta tatacacatt
    25501 cttattttct ccatactcta taaacgattc tatactacta tctgaattat ctttttgctc
    25561 tttaccaatt atattactga gtgtttgaat atgaatagaa aaatcatctt ttgataaaag
    25621 ttcttttata gctctctgtc tttctaagat tacattctca tctggatttt cattccacaa
    25681 atatttggct aaaaaatttt tcccataaga tgtattagct acacagatat attgatacaa
    25741 tgatgctctt ccaaataagt ctaaatcttt tgcttgcgaa ttttcatctt ttaagtattc
    25801 tttaccatct attttaaatt ccttccaacc atctccaaat ctcttaatat acttatttaa
    25861 tacttcgctc ttacttttaa aatatgtttc ttcttctttt actttactat gaataactaa
    25921 gagtgctata aatattatta ttgataaaac gccaacaaaa atacctacta tatttttatt
    25981 gtaaaatcca atagcaagcc ctgctatcac tatcaaaaaa gatattaatc ttgctgtact
    26041 tatgttattt gactttttac ttaagagcaa ttctttttca gtactacttt ctaaaagttt
    26101 actaaaatat tctattccca taaaaaattc caactttctt gttatataat gaaactcaaa
    26161 tataaaatta atctagtatt attataatct aacactgtac tttaaattat ccttatataa
    26221 tatatcttat taataaacat tatatatata caacttgatt ttaatttata aggtgtagaa
    26281 cataatccta atcaatattt aattaaatga tgtgtagttc actattattc agtactactt
    26341 agtatcgatt aattttgata attttttagt aaattcttga gctgcatcgt atcccattcc
    26401 tctttgtcta aaattcattg ctgctacttc taatatcata gcagtatttc ttccaggttt
    26461 tacaggtaca actaatttct ctacattaac accaagtatt tcttcatatt ctttatccag
    26521 tcctagtcta tcataatact tagtttcatc ccaagcttct aaatgaacta ctaaatctat
    26581 cattttagaa tttttgattg cccctactcc atataaactt ctaacatcta ttattcctat
    26641 tcctcttatc tcaagaaaat gtcttattag ttcaggtgac tgacccacaa gcatactttc
    26701 atctaatttt cttatttcta cagcatcatc tgcaactaat ctattacccc tttgaatcaa
    26761 ttctaatgct gtttccgact ttcctatact actttcacct tttatcagta cacctatacc
    26821 ataaatatct actagcaccc cgtgaattgt tgtatgtggt gctaacttat tatccaaata
    26881 gtttgacagt ctatttataa gtctagtggt atttctattt gtgctcaaaa gtattctttt
    26941 atatttttta gccttttcaa ttacatctgg cttgatttcc aagtctctag aaattattaa
    27001 cgctggtatt tcatatgaga aaaatctatc tagtacttct tctcgaatat gactatccat
    27061 taatccaaaa aaattatatt ctgtctttcc aactatttgt attctttcat atgcaaaata
    27121 atcaaaatat cctgcaaact gtaatcctgg tctatttata tcttgagagt agacataata
    27181 atctacatca tcaggcatgt atactacttt taacttcaac tcttttatta tctctcttat
    27241 tgatacttta ttgctagttt ccattaattt tcttcctttc taaaaaaatt ataaacatta
    27301 tctgcaatgc ttttattcat tccatccact tctaaaagtt cttccatagt agcttttttt
    27361 atagcatcta catctttaaa gtgatttaat aatgatttct ttcttttttc acctattcct
    27421 tgtatatcat ctaagataga ttttgtcaaa gctttatttc ttagacttct atgatatgtt
    27481 attgcataat tatgaacttc ttcttgtata ctagcaataa atctatataa attagttgtt
    27541 ttatctagtt ctatttcttt ttctttgcat atcaatcctt tagttctatg cttatcatct
    27601 ttgtacattc cccaaagagg tatatctaca tcattgagtt ctagtacttt ttttactgca
    27661 ctaacttgtc cttttccacc atccaacaat atcaagtcag gtaaatttcc atgttttaat
    27721 cttctatcta caatttcagc catagaatca taatcattag gtccaataac tgtctttatt
    27781 ttatatctcc tatattcctt cttatctttt ttagcattcg tatacactac catagaacca
    27841 atcgaatcta caccttgtat atttgatata tcataagcct ctattcttat tggcaacttt
    27901 tctagattta atatttgctt taattcttcc aatgctccaa tacttttttc atattttctt
    27961 ttattcatat cagaaaattt ttcaagatat tctacagcat ttttcctaac catttcaact
    28021 aagcttttct tctctccctt ttgaggaact cttattgtta ctttttgccc ctttttagat
    28081 gacagccatt cttctaatat agaactatct tctatctcat cttctataat taattcttta
    28141 ggtatatact cttgttcatt ataaaattgt tttacaaatg aacttaatat agaagctctt
    28201 ggactatcca ttaccccttc taatataaaa tgttccctac ctacaatctt accatttctt
    28261 ataaaaaata cctggacaca agcttcatta tgagctcttg ccattgcaac cacatcttgg
    28321 tttaagtcac ttacagtagc atctattttt tgtttctgta tcatctcttc aaggctcttt
    28381 atcttatccc tatatacagc agcctcttca aatctaaagt tcatagaact ctcattcatt
    28441 ttttccttta aaagttccat caatttttct tctttaccag ataaacacat tataatctct
    28501 tctatcattt ttccatactc ttctttagaa acatttcctg tacaaggtcc taaacattta
    28561 tttatgtgta gatttaaaca aggtcttgtc ttattcttta ttgctttatc tatatctatt
    28621 ttacagcttc ttattggata cgtactactt ataagctcca aggtatcatt cacagcagtt
    28681 atattggtat agggcccaaa atactttgcc ttatctttaa gaactcttct aacttttaag
    28741 attcttggat aatcttcatt cgtagttact tttatatatg gataagtttt atcatctcta
    28801 agcactacat tatactttgg tctgtatctt tttattaaat tacattcaag tattaatgcc
    28861 tctaactctg aatccgttat aatatactca aacttatata tattcttaac catagatttt
    28921 actttagatg tatggttttt tgaagattga aaatactgcc ttaccctatt ttttagagat
    28981 atggcttttc ccacatatat tatatggtcg tatttgtctt tcattaaata tactccgggc
    29041 tcagaaggta atttttttaa atgctcttgt atatcaaaca tctcgccctc caaaacatta
    29101 aattttatac taaaattata ccctaaaata tgaattttaa aaagttatac aatttccagt
    29161 gctttaaaca agttaaagcc catattccct tctataattg atttgaaaac aattttaacc
    29221 atgaagagta atatggactt tactttgtat tactatttac aacttatatt tgactaattt
    29281 acttataaca aaacagttta tcgtatatct gctctaaaat ttttcacaat ttatataact
    29341 taagaaaaat atttctttaa gaattgacct gtataagaac catcaacttt agatacttct
    29401 tttggtgttc cagttgcaac tatagttcca cccttatctc cgccttctgg tcctaagtct
    29461 attacataat cacaagtctt tataacatct aaattatgtt ctatgactat aattgtattt
    29521 cctgtatctg ctagtctttg taatacttgg attagcttgt ctacatctgc catatgaagt
    29581 ccagtagtag gttcatctaa tatatacaaa gtctttcctg ttggtctttt actaagttca
    29641 gcagctaatt ttatacgttg tgcttctcct cctgataatt gagttgaagg ctgtcctaat
    29701 ttaatatatg aaagtcctac atccattaaa gtttctaatt ttctttttat atttggtata
    29761 ttttcgaaaa actcaacagc ttcttccaca ttcatatcta atatatcaga tatagtttta
    29821 tctttgtatt ttacttgcaa tgtttctcta ttgtatcttt cacctttaca aatttcacaa
    29881 ggaacatata catctggtaa gaaatgcatt tctattttta ttattccatc acccttacaa
    29941 gcttcacatc taccaccttt tacattaaaa ctaaatctac cttttttata acctcttgct
    30001 ttagcttcat tagtagatgc aaaaatatct cttataaaat caaatacacc tgtataagta
    30061 gcaggatttg aacgaggtgt tcttccaata ggactttggt ctatatttat aactttatct
    30121 atactttcaa ttccttttat ctccttatgc ttaccagctc tttgcttaag tctattcact
    30181 ttacttgcaa cacctttgta aagtatatcg tttattaatg tactttttcc agaacctgaa
    30241 acacctgtta tgcatgtaaa cttacctaat gggaacttta catcaatatt tttcagatta
    30301 ttttctgatg ctttaactat ttctataaaa cttccatttc cttctctagt agtctcagga
    30361 agcaatattt gttttttacc acttaaatat tgacccgtta ttgagttctc attttcaatt
    30421 atttcatcta aagtaccctg tgcaactatt tcaccaccat gtatacctgc acctggacca
    30481 atgtctataa cataatcagc ttctctcatt gtgtcttcat catgctctac aacgattaag
    30541 gtatttccta aatctgttag atgtctaaga gtagttataa gcctatcatt atctctttgg
    30601 tgaagcccta tacttggctc atcaagtaca tataaaactc caaccaatgc agaacctatt
    30661 tgagtagcta atcttatacg ttgcgcttct cctcctgata aagttccagc ttttcttgat
    30721 aaatttaaat aatcaagacc tacatctctt aagaacatag ctcttccttt tatctctttt
    30781 ataatctcat gagctataaa tctctgtttt tctgtaagat ttatattttc cataaagtca
    30841 atcaattcat ttacagataa gtttgtaact tccattatat tttttccatc aactaaaaca
    30901 gataaaactt cctttttaag tctcatccct ttacactttg gacatggtct ctctgccatg
    30961 tattcttcaa tcttatctct catgtaatct gaattagttt ctctatatct tctctctaag
    31021 tttactatta caccttcaaa gtatgattta taatttctag ttcctccaaa ttttgactca
    31081 taagtaaact ctacaattat attatcttta ccataaagta attcctccac aaaatcatct
    31141 ggtaaatctt taaacggtgt tgtcaaagat acattaaaat gctctgctaa actttttatc
    31201 attttactgt aataagtgtc atcattaaca cctgttgaac cccatgctgc cactgcacct
    31261 tgttttattg ataaatcttt gtttggtact actaattctg ggtcaacttc tttactttcc
    31321 ccaagaccat tacaaacatc acaagcacca aagggagcat taaatgaaaa cattcttgga
    31381 gataattctt ctatgccaat tccatgttct gggcatgcaa atttagttga aaaaagaatt
    31441 tcttctccat ctattatttg ggctattaca agaccatcag atagcttaac tgcagtttca
    31501 attgaatctg ctagtcttga ttctattcca tctttaatta ctattctgtc cactacaact
    31561 tctatattat gtttttgatt tttatttaag attatatcat cactaacttc atagttttca
    31621 ccattaactc taactcttac aaatccttct tttttgatat tatcaaagac ttttttatgt
    31681 gtaccttttt gtcctctaac aattggtgaa agaatttgta atttcgttct atctggaaaa
    31741 tctagcattt tatcaactat ttcttgaata gtcatctgac ttattttttc accacatgta
    31801 gggcaataca catctcctac tcttgcaaat aatagtctca aataatcata tatttctgtt
    31861 actgttccaa ccgtagaacg tgggtttttt gaggtagtct tctggtcaat tgagatagct
    31921 ggtgataaac cctctatata ttctacattt ggcttttcca tctgacctaa aaattgtctt
    31981 gcataagcag atagactttc tacatatctt ctctgtcctt ctgcatatat tgtatcaaat
    32041 gccaaagaag acttcccaga ccctgacaaa cctgtaaaaa caataaattt atctcttggt
    32101 aattctaaat ctatattttt taaattatgt tcttttgctc ctcttattat aattttatct
    32161 tccataatgt tgtttttacc tttctatttt tccaattttt cttctaattg tttcacttta
    32221 tctctaagtt ctgctgctct ttcaaattgt aagttttgag cagcttccat catctctgat
    32281 tttaatttat ctatattagc tcttatttcg tctttatcat ctgtatcaga tattccatat
    32341 acaacttctt cctctgcaac cttagtagct tctatactat ctcttatatt tttctgtata
    32401 gttttaggaa tgatattgtg ctcttcatta tataaatttt gtatatctct tcttctcttt
    32461 gtttcatcaa tagcattttg cattgagtca gttatcctgt ctgcatacat aattactctt
    32521 ccattttcat ttctagctgc acgtccaata gtctgtatta aagctgtttc ggaacgtaag
    32581 aaaccttctt tgtctgcatc taaaattgct ataagtgaaa cttctggtat atccaatcct
    32641 tctctaagta agtttattcc tacaaggaca tcaaacttcc ctaatcttaa atctcttatt
    32701 atttctgttc tttctaatgt aactatatct gagtgtaaat atttaacttt tatccctatt
    32761 tctttaagat agttagtcaa gtcctcactc atttttttag ttaaagtggt tataagcact
    32821 ctttcatttt tttctatagt tttagttatt tctcctacca aatcatctat ttgattattt
    32881 ataggtctta cttctacaat tgggtctaaa aggccagttg gtcttattat ctgttctgct
    32941 attgtctctg agtgttgaat ttcataaggc cctggtgtag cacttacaaa caacatttga
    33001 tttatatttc cttcaaattc ttgaaaattt aatggtctat tgtcaagtgc agaaggtaat
    33061 ctaaaaccat tctctataag tgatgttttt ctagacctgt ctcctgcata catacctctt
    33121 acttgtggta tagtgacatg tgcctcatct acaattatca aataatcatc tgggaagaaa
    33181 tccattaaag tatatggtct ttctccttct gaccttcctg taatatgtct agaatagttc
    33241 tctatcccct gacaaaatcc tatttccttt aacatttcta tatcatactt agttctttgt
    33301 tcaattcttt gtgcttctaa tagcctatca ttttccttga aaaatttaat ttgttcttga
    33361 agctcgtttt ctatttctac aattgccttt tcaattcttt ctggcgttgt tacatagtga
    33421 gatgctggga atataacaac atgatttcta gtaccaacaa tcttccctgt tacataatca
    33481 atttctgtta ttctatctac ctcatcacca aaaaattcta ttcttattgc tttttcatca
    33541 ttactagctg ggaatatttc tagtatatct cctctaactc taaaggtacc tcgtgtaaag
    33601 tttatgtcat ttctttcgta ttgtatctct attaaccttt ttattacatc atctctgtct
    33661 ctttgcatac ctggtcttat agataacata agttctttat agtcttttgg gtcaccaagt
    33721 ccatatatac aagatacaga tgatattatt atagtatctc ttctctctaa aatagatgct
    33781 gtagcagaat gtcgaagttt atctatttca tcatttatgc ttgcatcttt ttctatataa
    33841 gtgtcactgt gagctacata tgcttctggt tgataataat catagtaact tacaaagtat
    33901 tcaactgcat tgtctgggaa aaattcttta aactcactgt aaagttgtgc tgctagagtt
    33961 ttattatgag ccattattag ggtaggtttc ttaacttgtt gaatgatatt tgccattgtg
    34021 aatgtttttc ctgaacccgt tacacctaat aatgtcgaaa atttctcatt tctatttata
    34081 gaatccacta ttgatttaat agcttctggt tggtcacctg taggtttgaa gtctgatttt
    34141 attttaaaat ccatagtatc actccttttt tcgaacatta gttcctgaca tgtattatta
    34201 tatcatacct ttataaaatt gtttaagtta ttttaaatat tttacccatt taaattttac
    34261 ttaaatctaa aacataaaaa aagacttcta tctttgcaat agaagtctat aattcatgga
    34321 aaataaatac tttattcaac ttacataata aaatcaaatg cttctttttc aactccatct
    34381 aattttaaat taaacatttt taatatagtt gctgcatgtg ctctcaggtc tccttcttct
    34441 ataaccacac cacctttaat atttggtcca aaagctataa atggaggtct attaccttta
    34501 gtaggtaaat gaccatgtgt cgcaacagca aacttgtaat cttttatatc tgaatctttt
    34561 ataatacttc cttcgaaatc atttccaaat gaaattcctt caagaccttc aattaccatt
    34621 tcaaaatcac cttcaagacc aaggttagat gcttcctctt tggtaaaaat attctctatg
    34681 aataattctt ctttaaattc ttcaagcagt tctcttaatt ctgttaacct atctaaatta
    34741 tttactatta tttgagctga tattccagaa gaatttacat aggcatcaaa atccttaact
    34801 tctccatttt caacttttat aaatccattt gatttaagca agacatttgg atttataact
    34861 ttatcaactc taagatgacc atggtcccca agtattataa aatttgtatc tttgtatgta
    34921 cctgcatcct ttgtagcctg aataatatct cctaaccatt tatcattcat ttttaatgct
    34981 ttatctactt cgtcattaaa taagccataa ttgtgtcgtg tatggtccaa tgtagctaaa
    35041 tgtattagca ttaaatctgg tttatattcc tttattatat ctactgaaca gtttactcca
    35101 aataaatcca tgttgggttc taatttccaa tcgatataat gacaatgtct attgtaaata
    35161 ccgtccatta taaccttact ggaacttcgt tcaaaagttt ctcttgggtc atcttctcta
    35221 ctaggagccc atatttctgc aatattataa tctatatttg gatttgctcc cattacaggc
    35281 cataatacac tagaggtagt tagattattt tcttttgcta catctataat agtttttgct
    35341 tttatgtcct ttgaatacca gtaccagtct ttattttctt tatttgggtc aaatttttca
    35401 ttatgatata taccatgttt tttaggatat actcctgtaa ccatactagt atgacacgga
    35461 tatgtcagag tgggataaac acaatttata ttttttacta tggagcaatt ttctagtata
    35521 gatttaaagt ttggtagatt ttttacaaat tccaagtctt tttcaaataa agaatctact
    35581 gataatacta taacctttgt catttacatt acctcttcat ttatatatta ttgaatactt
    35641 ttaatcaact tacaagtcta tataattatt tatttgtttt atctattact gcttgcattg
    35701 cagaagttcc tttgcttact acatcttttg gatttgcatt taaatcagta agcccctttt
    35761 taatctcatc cattagctta tcagttgctt ccttgtatcc atttaacatt ggaagtgcaa
    35821 cagcatattg taattggtca gttgcaacct tatattgagg tttttcttta tataatgttt
    35881 gtaacttttc tgagtttgtt gcatcttcag ttgttggtaa gtatcctgtt gatgaactaa
    35941 actgaacgat tttatctgtt tgtgtcatcc attctataaa ttctgcactt gcttcttttt
    36001 ctttatctgt tccaccttca agcataacta gattagctcc acctgtagga gttgcgtatt
    36061 tttgattttt tggtaagaat gctgttgata tttcaaactt accttctgtt tgttgcataa
    36121 gtcctgctaa atctgctgtt gatgtaaata tcatacctac tttaccattt acaaaatctt
    36181 gttttgctac atcccaggca ttataatctt ctccaggagg cattttcatt attccagctt
    36241 tcatcatatc ttgccagaac ttaactggtg cttgtcctgc ctcattatta aatgctactt
    36301 ttttaccatt agttatttct cctccacttt gcattaccat agcttcatag aaccaaatat
    36361 ctattggcgt ttcaaaacca taagtatctt ctgatttatt tgtcatttta ctagcataat
    36421 ccttaagctc ttcccatgat tttggacctg aagggtcaag acctgcttta gttgccatat
    36481 ctttatttat gtataatatt ggtgtacttc tattaaatgg cataccaaca aacttatcct
    36541 cataatatga atttgttaaa agaccagaaa agaatctttc ttgatatgtt ttatcaaaat
    36601 atttactcat atctactaaa gcacctgctg atgcgaatgt acctgtttga gttatttcta
    36661 ataatgttac atctggttgg tctttagatg ttaaggctgc ctgtagtttt gttgcatttt
    36721 catagtaatc tttctgtttt aacatattta cttgtacatc cttatgttca ctattaaatt
    36781 ggtcaaccat tttttgagca gtttctccat tagttccacc taaaggagcc cagaaatcta
    36841 tcttcgtaat attgctatca gtcttttctc ctttagatgc atttgcatca ttagaatttg
    36901 aacacccaac taaagaacct aataataatg ttattgctaa tcctgttgct aattttcttt
    36961 taagcttcat tttcatcctc caaatttagt ctttaatttt ttattttatt cctgaataca
    37021 taaaagcttc ttttactttt ttattcgcaa atatataaac aagaattatt ggtaaaatta
    37081 gaattatatt tcctgccatt attacattcc atgcagtaat tccttctgaa gatttaagga
    37141 gcgcaactcc tattggtaaa gttcttattg catctgtatt tgtcattact aagggccaga
    37201 aataattatt ccaatggtat ataaaattaa ataatataaa tgttattact gctggttttg
    37261 ccataggaac cattattcta aacattattt ttaagtcaga agcattatct agtttagctg
    37321 cttcaataat ttcatctgaa atctgcataa aattctgtct aagcagaaat atcccaaatg
    37381 aagatgtcat aaatggaatt ataagtggaa cataagtatt tataaatcca aacttactca
    37441 tcatcatata gactggtaga aaagttactt gtggtggaat cataagtcct acaagcaaaa
    37501 gcccaaatag cattttttca cctttaaatt taatcttaga aaatgcatat gctgctggaa
    37561 ccataactaa aaattgtaca attaaaacac ttcctgttac aaatacactg tttagcaaat
    37621 atctaaaaaa tggacctgaa tgccatgctg tactataatt ttctaacact atatcatttg
    37681 gtataatagt gggcggtaat tgcatcattt cttgtggatt tttaaaggat gtagatagca
    37741 tccatataaa agggaatata aatattgcag ataaaagtaa tagaattaat atttctattg
    37801 attttgatgc tatttttttt atatcaactt tgtctttttt gataggttgt ataatatcca
    37861 ttgtctcctc cttttggata aaccttataa tatctacttt ttctttattg ataatgaact
    37921 ttctttgata agagtctaaa gttagcatat gtagcaatca taactatagc taacaaaaac
    37981 atactcgctg cactcgcttg tcctatgtca tagtatataa atccagactc atatatataa
    38041 taagataaca tgttagttga acccactggc ccaccttgtg tcattatact tatctcatca
    38101 aatacttgaa aagatgcagt tgttgttgtt atcataagaa aaaatattgt tggtgataat
    38161 agtggcaatg tcactttaaa gaaattcgtt attttgtttg cattatctaa tttagatgct
    38221 tcatatatat agtttggtat ggatttaaga cctgataaca ctattaagat attatatcca
    38281 agagtcttcc atattcctat tagaattagt gacattaaag ctgaactttc acttgaaagc
    38341 cactttgatg ttggtaaatg taatgtcgat agtatccagt ttaaaaagcc atattgtggc
    38401 tccataatcc aaagccacaa tacagctaca gatactagtg aaattacatg tggtgtaaag
    38461 attatacttt gcgttaaatt gtgtattata gaatttttat ttagccaaac agcaagtact
    38521 atggctagtg atatagatat agtcaccata aaaaaagtat aaattgcagt gttcgttata
    38581 gtttgtataa actctggatt ctttaaaagt tctgtataat tgtttaagcc tacattttca
    38641 aaggttgaac taagaagact accagatttg aagcttagag atatcgtctt aattattgga
    38701 tagactataa acaataaagt tcctataata gcaggtgtta tatataaata tgctttatta
    38761 aattgctttt tcataaatat ctcctttaat tttagaatac atacttttac atacttttac
    38821 atcttctatt ctttctccat ttttatcaaa ataatataaa tctttttcta atacacttat
    38881 tcttaaagtt cttccaatat caaatatatc attttccgtt ttgactctta tctctctatt
    38941 aagaacagat aaacaatata tagtttcatt tcccaacact tctttagtta caacttttcc
    39001 aaatagacta aatacatcat catttttccc atctatgttt atactctcta gtgttgcttt
    39061 ttctggtctg aatccaaatt taatatcatt ttttatatct agtatgttca tacaaggact
    39121 ccctataaat tgagctacaa ataaattttt aggattttga tatatcttct ttggagaacc
    39181 tatttgcatt atctttcctt tgttcattat aactatctta tctgccatcg acattgcctc
    39241 aacctggtca tgagttacat aaacaaatgt agactttagt ttttgatgta attgtattaa
    39301 ttctgttctc atttgatttc ttaatttagc atctaaattt gacaatggtt catccattaa
    39361 aaataccttt ggatttttaa ccatagctct agcaagtgcc actctttgtc tttgacctcc
    39421 agataagttg cctggtttca catttaaata ttctctcaat cctactacat caataacttc
    39481 tgttataagt ttttctcttt tttctttttc tacttttttg tttttaagac caaattctat
    39541 gttttctcta acagtcatat gtggatataa tgcataattt tgaaatacca tagctatatc
    39601 ccttttacta gcatccgttt ttgtaacatc attttcttca atcttcaacc tacctgaagt
    39661 tatatcttca agacctgcaa tcattcttaa cgtagtagat ttaccacatc cacttgggcc
    39721 taccaatact gtaaaagaac catcttctat agtaagattt aaattttcta taactgtatt
    39781 ttttttatta taagattttg ttacattttc tagtcttata tctgccattt ttatcctccc
    39841 aaaatattta atttaattct acgatttact tatagattaa taatactctt aatttgtaaa
    39901 ggatatatta agacaaagtg aatatatggt aaacttatta aaataaaggt taaattataa
    39961 acattttttg ttaaatatac tgaggttaag atgatataca gcttatgtta gctataattt
    40021 tctatatttt tcatattcat ggtttgctat cacaatgtaa ttttaattta tgaagagtca
    40081 tataaaacta tttatttttt atataatttg atttgaaagt aaaaaagacc tctatggggg
    40141 atagaggtct ttaagtgggg gagattgagt aatttatttt tgctatatta agttttacaa
    40201 ttatattatg tcccaaattt acaaggttta aacataaaaa ataaaacttt tttaattttt
    40261 ataaatttac ccaaaaaaaa t
//
LOCUS       DAEPUT010000035        39915 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.036, whole genome shotgun sequence.
ACCESSION   DAEPUT010000035 DAEPUT010000000
VERSION     DAEPUT010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39915
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.036"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..1332)
                     /locus_tag="KRL22_001909"
     CDS             complement(<1..1332)
                     /locus_tag="KRL22_001909"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBH1272401.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYT"
     gene            complement(1481..3286)
                     /gene="lepA"
                     /locus_tag="KRL22_001910"
     CDS             complement(1481..3286)
                     /gene="lepA"
                     /locus_tag="KRL22_001910"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBH1272402.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            complement(3568..3819)
                     /locus_tag="KRL22_001911"
     CDS             complement(3568..3819)
                     /locus_tag="KRL22_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272403.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            complement(3850..4869)
                     /locus_tag="KRL22_001912"
     CDS             complement(3850..4869)
                     /locus_tag="KRL22_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HBH1272404.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSRENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            complement(4887..5840)
                     /locus_tag="KRL22_001913"
     CDS             complement(4887..5840)
                     /locus_tag="KRL22_001913"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HBH1272405.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            complement(6183..6959)
                     /locus_tag="KRL22_001914"
     CDS             complement(6183..6959)
                     /locus_tag="KRL22_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1272406.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            complement(6993..7514)
                     /locus_tag="KRL22_001915"
     CDS             complement(6993..7514)
                     /locus_tag="KRL22_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1272407.1"
                     /translation="MDIAKLILNPARLRILQYIRLHSSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            complement(7924..9576)
                     /locus_tag="KRL22_001916"
     CDS             complement(7924..9576)
                     /locus_tag="KRL22_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH1272408.1"
                     /translation="MKIYKKLLTTGISFLLVISAFPIVSNALSSIDSIKGKDKYETSA
                     IIADKQNYTKAILINVDNSLADGLSASGLAGVENAPILLTKKDEIPDSTLKRLNNVKK
                     VYIIGGNNSIGSKVDNLLKKKNIEVERIEGKDRLSTSYKVSDKILELKGTSGNVLVAN
                     GFKGEADAISAASVAFKNSIPVLLTNGSDMPELKIKGDKIFAFGSTNTMSNQLVEKLG
                     AIRLGGIDRYETNKKIVQQFYGDAKEFYVASGSDLVYPLIGSTLAERKPIILVGNGSN
                     KSILKGATKITSIGNVDASIITQCLNVTNNIGDINTGMVKTNTNKEYPIKGMLAKFGL
                     NTTGKIGWALMYGGNGNGVELRADGKYYHINRGNTALGAYAAALAGEKYHSLDFGDLD
                     PIEIIADKEEISYEKAKKEIVVIRNFLNSFDWQNASDLEKATRAGKLVTEADYVMGNY
                     NIYTNLLEKKSVCEGFAKSFYVLTRLMGMDSIYQEDGRLNHAWNYVKIDGKWYEFDGT
                     EAGSYKDLGIKVEFNSSKLEEATKQMPKYYDAKALSVLGFNQ"
     gene            10010..10276
                     /gene="rpsT"
                     /locus_tag="KRL22_001917"
     CDS             10010..10276
                     /gene="rpsT"
                     /locus_tag="KRL22_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBH1272409.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            complement(10463..11506)
                     /gene="holA"
                     /locus_tag="KRL22_001918"
     CDS             complement(10463..11506)
                     /gene="holA"
                     /locus_tag="KRL22_001918"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBH1272410.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(11460..12713)
                     /locus_tag="KRL22_001919"
     CDS             complement(11460..12713)
                     /locus_tag="KRL22_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HBH1272411.1"
                     /translation="MFVVAISFIITNNTKNDEELNDKIITIQGVVKGKIEKKRYNQYK
                     VGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGRYIKSTGYKGIVYINNY
                     KIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEVENLTEEQKEIFTRTGT
                     SHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYCIMVGASPSIIRSIAFV
                     MIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLSFLATLSILIFYNKINS
                     IIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPFVGVIMYLSIASLIVFK
                     VSVVIAKIISFFNSTLIESIFFLLEKISNLSFAYINIENPKFYIVVIYYIGVFFYIFY
                     IEGKEIKEQENELQGYYKECKREKL"
     gene            complement(12876..14060)
                     /locus_tag="KRL22_001920"
     CDS             complement(12876..14060)
                     /locus_tag="KRL22_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1272412.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKIYIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            complement(14069..14974)
                     /locus_tag="KRL22_001921"
     CDS             complement(14069..14974)
                     /locus_tag="KRL22_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HBH1272413.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            15162..15998
                     /locus_tag="KRL22_001922"
     CDS             15162..15998
                     /locus_tag="KRL22_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1272414.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKKLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            complement(16143..16847)
                     /locus_tag="KRL22_001923"
     CDS             complement(16143..16847)
                     /locus_tag="KRL22_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HBH1272415.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLG"
     gene            complement(16998..17094)
                     /locus_tag="KRL22_001924"
     tRNA            complement(16998..17094)
                     /locus_tag="KRL22_001924"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17058..17060),aa:Sec,seq:tca)
     gene            complement(17338..18177)
                     /locus_tag="KRL22_001925"
     CDS             complement(17338..18177)
                     /locus_tag="KRL22_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBH1272416.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            complement(18426..19100)
                     /locus_tag="KRL22_001926"
     CDS             complement(18426..19100)
                     /locus_tag="KRL22_001926"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBH1272417.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            complement(19137..19508)
                     /locus_tag="KRL22_001927"
     CDS             complement(19137..19508)
                     /locus_tag="KRL22_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBH1272418.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            19575..20633
                     /locus_tag="KRL22_001928"
     CDS             19575..20633
                     /locus_tag="KRL22_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBH1272419.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKNGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            complement(20824..22002)
                     /locus_tag="KRL22_001929"
     CDS             complement(20824..22002)
                     /locus_tag="KRL22_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBH1272420.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(22056..23120)
                     /locus_tag="KRL22_001930"
     CDS             complement(22056..23120)
                     /locus_tag="KRL22_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1272421.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YAGNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            complement(23225..24487)
                     /locus_tag="KRL22_001931"
     CDS             complement(23225..24487)
                     /locus_tag="KRL22_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH1272422.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            complement(24512..24829)
                     /locus_tag="KRL22_001932"
     CDS             complement(24512..24829)
                     /locus_tag="KRL22_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH1272423.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            complement(24888..25343)
                     /locus_tag="KRL22_001933"
     CDS             complement(24888..25343)
                     /locus_tag="KRL22_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1272424.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDERLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            complement(25358..27247)
                     /locus_tag="KRL22_001934"
     CDS             complement(25358..27247)
                     /locus_tag="KRL22_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1272425.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAIKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            complement(27335..28696)
                     /locus_tag="KRL22_001935"
     CDS             complement(27335..28696)
                     /locus_tag="KRL22_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1272426.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            28869..29813
                     /gene="manA"
                     /locus_tag="KRL22_001936"
     CDS             28869..29813
                     /gene="manA"
                     /locus_tag="KRL22_001936"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBH1272427.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            complement(29932..32670)
                     /locus_tag="KRL22_001937"
     CDS             complement(29932..32670)
                     /locus_tag="KRL22_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HBH1272428.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIVSGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(32775..34658)
                     /gene="selB"
                     /locus_tag="KRL22_001938"
     CDS             complement(32775..34658)
                     /gene="selB"
                     /locus_tag="KRL22_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBH1272429.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEENIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            complement(34772..36184)
                     /locus_tag="KRL22_001939"
     CDS             complement(34772..36184)
                     /locus_tag="KRL22_001939"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBH1272430.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            complement(36202..37248)
                     /gene="selD"
                     /locus_tag="KRL22_001940"
     CDS             complement(36202..37248)
                     /gene="selD"
                     /locus_tag="KRL22_001940"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(37198..37200),aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBH1272431.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            complement(37340..38044)
                     /locus_tag="KRL22_001941"
     CDS             complement(37340..38044)
                     /locus_tag="KRL22_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HBH1272432.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            38124..39413
                     /locus_tag="KRL22_001942"
     CDS             38124..39413
                     /locus_tag="KRL22_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1272433.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            complement(39540..39878)
                     /locus_tag="KRL22_001943"
     CDS             complement(39540..39878)
                     /locus_tag="KRL22_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HBH1272434.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
BASE COUNT        13005 a         6805 c         4191 g        15914 t
ORIGIN      
        1 tgtatatata tttaatgctt tttcttttag tatttctttt tcatttaact ctggattatt
       61 tatgactatt tcaagcatct tatttaaaat atatcctata tctttacctg gttttatacc
      121 tatagatatc aaatcttttc cattaatagc taaatcttta agattaaagc actccttttg
      181 atttattata tgtttaaatt ctttttcaca ctcaataaga tttaatatct tttgttttgc
      241 atactttgga ttttttgcaa gtgtatcagc ccaattaact tttattaaat cttcaaataa
      301 ttcaacatct tcaagtttat ttaataactt tttaattatc ttccttttag gttctattct
      361 ataatcatga tattgtatta atattaaaac tttattaata gtataattat catacttaag
      421 tcttttcaaa atcttctttg caatctttac agattctcta ctatgagtat aaaaatggtc
      481 aacaccattt ttatcagttg ttttagttac ttttttacct aaatcatgaa acaacattgt
      541 aagttttaaa tacagttcat cttcaattac ttctgtagct attaaagtat gtttttgtac
      601 atcatagatg tgatatggat tgtgttgagt aacatcttct aattcacata tttcaggaat
      661 tataaatttc aacaaacctg ttgattttaa taagtttaat ttagatgaat cagatactaa
      721 tattttatta aactctgtct ggattctttc aatagaaaca ttttttatca aatctgcttt
      781 tttatgaata ctttgcttag taccttcagc tattttaaaa ttgagttgtg ctgaaaatct
      841 aactgctcta agcattctaa gtgcatcttc ttcaaatcta tctactggat ttccaacaca
      901 acgtatatac ttattttgta tatcttcata gccattaaat gggtcgacta atcctgtctt
      961 tgaattgtat gcaattgaat tgatagtaaa atctcttctt gacaagtcct taactatgtt
     1021 atttgtaaat tctattgaat ctggatgtct accatcacta taatttccat caattctata
     1081 agtcgtcact tcaaatggtt catgttcaat cataactgtt acagtcccat gttgtatacc
     1141 agttggaatt gttttttcaa ataattctac taccacttct ggtctagcac tagttgttat
     1201 atcccaatcg tttggaactc tttctaataa acaatctcta acacatcctc caactatata
     1261 agcttcataa ccattctttt ctaattcttt aattatatag tctacttttt taggaatttc
     1321 tatattaatc ataaatatca cctttttatt cttctttaat attcttactt atattctcta
     1381 tgagtttact taaaatatac cataaaaaag ctagactaat ttagaaataa ttctaaaatc
     1441 actctagctt ttaaatatct ttatctaaat ttataaggat ttactcatct aatttaagca
     1501 cagacataaa tgctttttga ggaacttcaa cagaaccaat ttgtctcata cgcttcttac
     1561 cttctttttg tttttcaaga agtttcttct tacgagatat atctccacca taacatttag
     1621 caagaacatc ttttcttaga gcgcttattg tttctcttgc aataacctta ttaccaacag
     1681 cagcttgtat tggtatagca aactgatgtc ttggaatttc tccttttaat ttctcacaca
     1741 ttgcctttcc tctagggaaa gcacgtgtct catggacaat aaaactaagt gcatccactt
     1801 gctctttatt gattaatata tcaagtttta caagtgtaga tgctacataa cctttaacct
     1861 cataatcaag agaaccataa cctctagttc ttgattttaa agcatcaaag aaatcgtaaa
     1921 caacttcatt gagaggaagg tcatagtgaa gcattactct tctatcatct atatattcca
     1981 tatttaacat atttccacgt ctttcctggc aaagctccat aacaacaccc acatagtctt
     2041 taggaactat tatatctcct tttactatag gctcttctat catctttatc tcagatggtt
     2101 ctggtaagtt tgcaggattt tgtatcatta caacctctcc atccattttt gtaactctat
     2161 atataacaga tggagctgta gtaattatat caaggttaaa ttctctctca agtctttctt
     2221 gcattatctc catatgtaaa agacctaaga aaccacatct aaaaccaaat cctagtgctg
     2281 ctgaagtctc agcttcatat tcaagtgcag catcatttac ttgaagcttt tcaagagcat
     2341 ctctaacatt ctcatacttt tctccttctc ctggatatat accacaatat accattggag
     2401 tagctttttt gtatcctggt aaaggttctt ctgtaggatt atttgaatct gttattgtat
     2461 caccaacacg acaacttctt atatctttta tactagcagc aatataacca acatcacctg
     2521 ctgataattc actaagttca gtttgacctg gagccatgac accaacttca gttacctcaa
     2581 actttttatt ggtattcatc atttttattg tcataccctt tttaacagtt ccttcaaata
     2641 ctctaacata agctacaaca cctttgtaag catcatagta agaatcgaat attaatgcct
     2701 ttaatggagc ttcattatct cctttaggtg gaggaacatt ttttacaata tcttctaaaa
     2761 catcttctat gtttaaacca gttttagctg aaataagagg agcttcactt gaatcaagcc
     2821 ctattaaatc ttctatttca ttttttactt cctctggtct tgcacttggt aaatctattt
     2881 tatttattat tggtaatatt tctaaatctt ggtctatagc aagataaaca ttggctaaag
     2941 tttgtgcctc aacaccttga gctgcatcaa ctactaatag tgctccttca catgcagcta
     3001 aacttcttga tacctcatag ttaaagtcta catgtccagg tgtatctata agatttaaat
     3061 aatattcatt tccatccttc gctttataca ttaatcttat gttttgaagc tttatagtga
     3121 ttcctctttc tctttcaagg tccatattgt caagtaattg acttttcatg tctctttcac
     3181 taacaagccc agtttgttgt attaatctat cagctaaggt agactttcca tggtctatat
     3241 gtgcaattat actaaaattt ctagttctac tttgtttatt gtccacctta aaattccctc
     3301 ctcttgatta ttcttatagt tattatttta cattatctaa aaactcttta tataccaaat
     3361 ttaaaatttt tgaatataaa ctaattggca ctaaacaaaa ttatccacat tatatgtgga
     3421 ttatcaagtc taacactaaa tattatataa tatcgtaaac ttaaagtaaa tcctataaaa
     3481 tacagttaat gaatttttat tttatacatt aaaaatatat aactaaaata aggcttattt
     3541 taatcaataa accttattca cttattacta cttattaaat ttttttatga tttcatgtat
     3601 atcaaaattt ggtatgtcaa aatcaaattt tgttatatca aatttaatac ttggaaaatc
     3661 atattgtttc attcctagca tactttttgc attactgtcc actataaata cacaaactga
     3721 tgtacatata atcatagtaa tcaaaaataa gattctcata atatacttgt attttcttag
     3781 tttactttta ctttctatat ttttttctaa tcggctcatt tagcatgctc ctaattataa
     3841 cttaaagctc taattttttt gtttaaaata ttcatccaaa atctcggcta aatactttgt
     3901 agtagcctta gattcttcta cacttgttgc gttattccct atttctacta acatatgatt
     3961 cttaactgca aactgattga atctagcata gtctttttct actattggag atactagacc
     4021 aggatacttt ttctcagcaa aagcagttat atcttctgct aaagctctaa gttgttttct
     4081 atttgtattt ttacctccta caacaaagaa gaactttgat actctctctc catttatcat
     4141 agttgtatat tttaaatggt ctttttcctt agtggctgga ttagttaaat ccctagcatc
     4201 tctatgtaag tctatcgcta tatccactga gttatattta ggtaatatac tttgtattgt
     4261 ttttaagcta cttgcataag agttattata agatggatag tcatggtatt tagtagtatg
     4321 gactacaccc catcctttgc tatctaaagc actagttaat gcacttccta cttccattac
     4381 tgaatttttc ttatctcttg aatgataatt tccatcaggt gaatttgaat aagtctcaca
     4441 tccatgagta tgatatatca aaattcttgg attttctttg gttactctta aatcatcctt
     4501 ataatctgaa ctagatgttg tgttagtttc agttgtgtct gaattttttg actcaatatc
     4561 tggaacattt tctttaccaa cataaagttt tatatattct ttttcactct cttttttatt
     4621 atcaacttta cttgcatctt tagatttagt gtttccttct ttactttctt ccttattttc
     4681 cctacttgtt tctttatttt tattattctt tttattttct gtatcatttc cttcgacttt
     4741 agcttctgga taagatgaat ttactaaaaa ctttaaaaaa tcatcttgat tcaaagctaa
     4801 tgattttcct ggtaaaatgc atactaatat aaaagtcaag gttactactt taatgcattt
     4861 tttaaacata attgctcctc cttattttat accaatctac ctggatgtaa agacctattt
     4921 aagccttcac ttattattat agatagattt tcgattgtat catctatatc ctttggtgtt
     4981 actattaagt tcttgtcata tgggtctaac gaatctttta ttagatgata tttttcttct
     5041 tctttaagtt ttttcaacat ttcataaaaa ctttctgttt cttctgattg agctattaaa
     5101 ttgtctattg ccatatctaa gacatctatt gtaagagttg ctgcatcaac cactgttgga
     5161 acgcctattg caataacatc cacgcctaaa gtttctttag ttagagattt tctagtattg
     5221 ccaacacctc caccaggtga tattcctgct gttgatatct gtatagtaga gtttactctc
     5281 tccatttttc ttgaagccaa tgcatctatt gctactactc tatctggctt aaccttctca
     5341 accaatgatt ttactatttc actagtttct attccagtaa cacccataac tcctgggctt
     5401 aaagctgata cctcagtgaa atcatcatca tagtctttat tataattttt aaaaagatgt
     5461 ctagttacaa gtgtttttga tacactcttt ggtcctaacg catcagaagt aatatttcta
     5521 tttccaagac caattaccag ggttttttta tttttgtctt ggccaaatat atctactaac
     5581 tcctctttta aataacttat catttcttct cttgactcat catcatcaaa cttcataaga
     5641 ttactttcca gagttatata ctttcctata tctttattca ttatctctgc gccttgcctg
     5701 tctattactt caactttagt tacaatgcaa ttttctaatt ctttagtttc tatttttaca
     5761 ccaggaatac tacttccttc ttgagacttt tcacacattt cactagcttc taaagctaaa
     5821 tctgttctta cactaatcat ataaacctcc agtataaatt aaatgctaat tataattgtt
     5881 aacaaaattt agtattttat aacaagaaat tgtaaattta tttaaaacaa gtaaaattaa
     5941 ggctttcaat gtaagaaaat tgggtttagt cagtgatttg tcagtaaacc ttcttatcta
     6001 tcatttattt acaaacagaa aaaggtagca actatttata taggcgctac ctttaatcta
     6061 tttataattt tcctattaag ctttcactaa tatattaact aaaataactt ttttatattt
     6121 atacctaatt tatttactat attaaaaaac agcaataatt atacaataat cacctaacac
     6181 ctttattcct tttggaaaaa tggttctgca atttccaacc attcatttgg aagataaagt
     6241 gataaatatc catgattata gctcttagct tcataaatct cacaagaagg cacataagac
     6301 tgaaacagtt ttgcagattt tttgacacac ttcatttctt tttctccata ccagtacatt
     6361 acttgtgctg tggttttttt aacattctct ttaagtgtat agttcatcat ataagtacga
     6421 tacatattat agaatgtttc ttttcttaca tgtggcatat ctgtcatata atacgctttt
     6481 atttcatctg gatattgcat attttcaggt aacaattttg gcatcatagc aatttgaaag
     6541 cgacaagcct tctcactaaa caaaagtcct ccaaaaaatc gaataccagc aatacaaaac
     6601 cttgccataa gaggtcttgg gtagcaaata ctaccatcaa taattgcttt tttagtaata
     6661 ttaggttttc gagataaaag ttccatgaca atttgaccac caagtgatac accacacaaa
     6721 gcgaaaagat gtccactgca attttcatct atatatgata tcaacttatc tgctgtatcc
     6781 tctgtagaaa tgtatgttgt ttcatattct tctccatgac catccaatgt aggaagtatc
     6841 acatgatatt tgttagacaa aacttctgct tgtcgcaaat agttccacca tgcattccct
     6901 cccccatgaa tcaacataat atgtggtctg tttttatttc caaactcatg aaatttcata
     6961 tataacctcc ttttataaaa atgggttgca tgttattttg ttttatcatt atcagctaca
     7021 ggtggagaag atataattga aagttttcta agttttagat ttgatttagg tttttgttct
     7081 atatatggtt tcaataaatc agctatactt ttaagaagat tttcatattc attatcactc
     7141 atatatagta atgctgaaga gaaaaataca ttatcctttt tatggtcttg ctcttttctg
     7201 ctaaagtatt cattcatttc ctgcatcaga cctacataaa atgctgtaga aagtgcaacg
     7261 aaggtctctc cttccataga tgttgtatat tcctttagtg cataaacctt ttcaatagta
     7321 ccacgcacac gattttcttt aattacttca atcatattgt tctcttctaa aatttttaca
     7381 tggtgataaa ctgttgcacg aggaatatca tttaaatact ttacaatatc agatgtgcga
     7441 acactgctat gaagtcgaat atattgtaaa atacgaagcc ttgcaggatt taaaattagt
     7501 tttgctatgt ccatcttatc agccctttct ttagtctata aaaatattat agtctatttt
     7561 tttagactat tcaagtctat gatataaata gtaattacaa ctataataaa tgctattcta
     7621 tataaacact gacattaatt gcatataacc ttccaacata ttagttatat tgtttggtat
     7681 atttatcata tacaccaatg taatttaatt tcagtttatt taattccaga acgcttaaag
     7741 tttcttttgt aataacattt gtattactat tttcattttc tatttatata aaaatatata
     7801 aataaatttt ctatgccatt taagtacatt atataaaact atcaaatagt caacagtaat
     7861 tattcaacct taaaaataat tttggaacat ttaaaaagaa agactctttg aagagtcttt
     7921 cttttattga ttaaatccta atacagataa cgcctttgca tcatagtact taggcatttg
     7981 ctttgttgcc tcttcaagtt tagaagaatt aaattctact ttaattccca aatctttata
     8041 tgatccagct tcagtcccat caaattcata ccatttacca tcaattttta catagttcca
     8101 agcatggttt aatctaccgt cctcttgata tattgaatcc attcccatca gtcttgtcaa
     8161 tacataaaag ctttttgcaa aaccctcaca tacacttttc ttttcaagga gattagtata
     8221 tatattataa tttcccataa catagtctgc ctctgtgacc aattttccag ctctagtagc
     8281 tttttccaaa tcagaagcat tttgccaatc aaagctattt aaaaaattcc taattactac
     8341 aatttctttt ttggcttttt cataagaaat ttcttcctta tctgctatta tttctatagg
     8401 atcaaggtct ccaaagtcca gactatgata cttttcacct gctaatgcag cagcatatgc
     8461 acctaacgct gtattacctc tatttatatg ataatatttt ccatcagctc gaagttcaac
     8521 tccatttcca tttcctccat acattaaggc ccacccaatt ttaccagttg tgttaagacc
     8581 aaactttgct aacatccctt tgataggata ctctttattt gtatttgttt tgaccatacc
     8641 tgtattaatg tcccctatat tattagttac atttagacat tgtgttatta tagaagcatc
     8701 aacatttcct attgatgtta ttttagtagc acctttaagt atacttttgt tacttccatt
     8761 tccaactaat ataattggtt ttctttcagc tagagttgag ccaattaatg gataaactaa
     8821 gtcactacca ctagctacat aaaattcttt ggcatcgcca taaaactgtt gaactatctt
     8881 tttattagtc tcatacctat caattccacc taatcgaatt gctcctaatt tttctacaag
     8941 ttgattactc atagtatttg ttgaaccaaa tgcaaatatt ttatctcctt taattttaag
     9001 ttcaggcata tctgaaccat tagtaagtaa tacaggtatc gaatttttaa atgcaactga
     9061 ggctgcgctt atagcatcag cttcaccttt aaacccattt gctactagta cattacctga
     9121 agtacctttt aactctaaaa tcttgtcact tactttatag cttgtactaa gtctatcttt
     9181 tccttcaatt ctttcaactt caatattttt cttctttaat aagttatcta ctttgcttcc
     9241 tatagaatta tttcctccta ttatgtacac ttttttaaca ttattaagtc tttttaatgt
     9301 tgaatctggt atctcatctt tcttagttaa taatattggt gcattttcaa ctccagccaa
     9361 tccacttgct gataatccat ctgctaaact attatccaca ttgataagta tagctttagt
     9421 ataattctgt ttatctgcaa taatagctga agtttcatac ttatctttac cctttatact
     9481 atcaattgaa ctaagtgcat ttgatactat tggaaaagca gaaatcacta gcaagaatga
     9541 aattcccgta gttaataatt ttttatatat tttcataata taaatacctc ccagatatta
     9601 tagttccact taaataatat actataagat gaaaaaaatc accttgatta aacatataaa
     9661 tttatatttt tataaatttt ttattaaatt caaaaaaatg agtaatttct tgtattatct
     9721 tataattatt ggaaatacta tcaaaatgta tgttaatagt ttgtattatc tcaaatattt
     9781 gttacaaaat gaaatattaa ttatatatgt caaaatattt aaaacacaaa atataccaat
     9841 ttaaaaacaa gatattgcaa attatttata cacaatttac agtctaaaaa atcaaaaaaa
     9901 aacattatta aaatatataa ataataatcc ttgattttta gatttatttc tgttaaaatc
     9961 taatatgttg acgatgaata tgataaaaaa atacagggag gtgaacacgg tggcaaatat
    10021 aaaatcagct aagaaaagaa taagtgttat cgaaaagaaa actgctttaa atagagttag
    10081 aaaatctcaa ataaaaactg caataagaag attcgaagat gctgttgcag ctggaaacag
    10141 agaggatgct gttgctaagt tccaatacgc tcaaaaaaga atataccaag tagcttctaa
    10201 aggaactata cataagaatg ctgcagctag aaaagtagct aaattagctc aaaaattaaa
    10261 cggtatgaac gcttaattac cagtttatat ttcttatata taataacccc tatgtagggg
    10321 ttttttattt tgtaaattta tacaataaaa aataaatagt tagacatatt atagttgatt
    10381 gtatatcaaa cttaatttag cttacatcta ctctgaacta taacatatct tgctatttat
    10441 tttttattaa tatatagatt ttttaaattg cttctctttt acagtatcta ctaaccaaca
    10501 tttcaactgc taaagtatct cttataagac ctgtctttat tttgtaatca ctttctaata
    10561 tatagtttaa tatttccaca attatatcat cagaaaaatt tttagtttgc tttaatgctt
    10621 ttcctacaac aaattgatgc atttttaatt tatcagctat aagttttgtt gaatatccat
    10681 caagttgtaa ctgtcttact tgcataatta ttttaaattg tcttgctatc atagaaaata
    10741 tacctaatac agattcgcct tcttgtatca tatcatttaa tattttcatt gcattagaag
    10801 cattttgttc tccaatataa tcgattaatt tgaatatatc attctcaact tttttttgag
    10861 ataatttatc aattacatca ttggttacat tattcccttt accaacaaat gaacttattt
    10921 tatttatttc attttctaaa tcagataatg tcttttcact actcttatct ctgtatcctt
    10981 cttgttcaat aaaatacatg atttgagaat tatctattat aacatcattt aaagcaaaag
    11041 atttttttat ccatttaaac aaatccatat cagaaagctt atcacaatca aaaacaattc
    11101 cattgttccc tattttctta actaatgatt ttcttttgtc tacatctcca tatacaacaa
    11161 aaactatagt tgtggtgtct ggaatattgt ctaaatgctc tattaagtat ttctcatcac
    11221 tatctgtaaa attctttttc tttcctttta atagttcaaa gtcttttatt attactatct
    11281 ttctatcatc cataaatgga agtgtttcta tagagcttat aagctgattt aagactattt
    11341 ccttcccatc tattatatct aaattaaaat caagcattcc ctcgtttaaa ctatctttaa
    11401 atgcttttat tgcattctca attaaataat actctcttcc ataaaaaaga tacatttttt
    11461 caaagttttt ctcttttaca ttccttataa tatccttgta attcattctc ttgctccttt
    11521 atctcttttc cttctatgta aaatatgtaa aaaaacactc ctatgtaata aataacaaca
    11581 atataaaatt taggattttc tatattaatg tatgcaaaac ttaaattgct gattttttct
    11641 agtaaaaaaa atatgctttc tatcaatgta ctattaaaaa aagatataat tttagctatt
    11701 actacactta ctttaaatac gattaaactt gcaatactta aatacattat tactcccaca
    11761 aatggtacta taattaaatt tcctataatt gaaagcaatg gtataccttt aaatgtataa
    11821 taaattatag gtaaagttaa tatatttgat gatattgtca atgataccat acttaatttt
    11881 ataatactat ttattttatt atagaatatt aatatagaaa gtgtagctaa aaaagacaat
    11941 tgaaaactta cattatatat aacatagggg ttattcataa ttaaaattat cccaattaga
    12001 gacaatgccg atattccatc tttctttcta tcaataaata ttgataaata aaaaatcata
    12061 acaaatgcta tagacctaat tatggatgga gacgcaccta ccattataca atataaagtt
    12121 ataaaaatcg acagtattaa taatttatac aatttattta tacctcttaa tagaaaggat
    12181 ataattacac ataatattcc tgtatgaaga cctgatatag atattacatg actagttcca
    12241 gttctagtaa aaatttcttt ttgttcctca gtcaaatttt caacttctgc taatagtata
    12301 gaatttataa aatctgagtt tttcttatat aagtacctat aagttttact aatataaaac
    12361 tttatttccc ctattaaaga gtaaagttta tttttatcaa taattttata gttatttata
    12421 tacactatac ctttatatcc agtacttttt atataccttc cataatcaaa atcatcatac
    12481 ttcattttat ctaaactttt gaatttacct gtaatattaa ctttctgacc aatcttcaaa
    12541 tttttatttt ttgtataatc atttattaga aaaaccccta ccttgtactg attgtatctt
    12601 ttcttttcaa tttttccttt gacaactcct tgtatagtta ttatcttatc attaagttct
    12661 tcgtcgtttt ttgtgttatt tgtaatgata aatgatatag ctaccacaaa cattaatata
    12721 attaataatg gtcttcttat ttgaattata atcactccta tataaaagta tattatttag
    12781 attattttca aatagaaaat ttttaaacaa gataaattgt tatctaaaca aaaaaatacg
    12841 tcaaaagatt tttaaaatct tttaacgtac tctacctata tatattcatt tatatagtta
    12901 ttttttttag aaaaaataca attaagtgtt tctagtgttt cttctgaaac atcttttata
    12961 tcatttaaga aaatagcttc atttacatct atataagaaa atgataactg tgttaaggta
    13021 tttatatcta atttaatatc aaaatcttct tgaggctttt ctgcaccttt tttatctaac
    13081 tgctctacag ataccttctt attctgtata taaattttaa atagaccatt attttcatct
    13141 ataaacttgt cttctattaa taaattaaat gagctattaa tatccttctc aatatctata
    13201 tcttcaataa acttctttac atttataact cttcccatca taaaaggttt tatttttata
    13261 tcactatctt tagggttgtc taatataaat cttatcttat ctattgtagg agtagatata
    13321 gtaactatct tacattgagt attgtgatta tatataaatt taagcattga tttaagggca
    13381 tctatatttt tataaaataa ctctctgaca aacattttat cttcctgaag aaaataaact
    13441 atatatccat ctttttcatt tccttcatga atgtataaaa atccatcttc actttgaatc
    13501 tctttaaata agttttcata ataatgttca tcttttaaca cattaccatt aacctcattt
    13561 aaaaaagttc tatctatttg tatcaaatca tcaatttgtg ataaattaga ctttatcatt
    13621 tttccacttg acttaaaatt ttttaaatca tctgtgttaa tagtatattc aatctggtcg
    13681 taacaatgct catatccaaa tcttctataa agtctatagt caataggcat caatatagaa
    13741 actaattgcc cttttttata caattcgttt aaagtaaatt tcattacttt gttcatatat
    13801 ccagctcctc ttccctctgg aagtgtagaa actcctacta catatgatgt attatatacc
    13861 ttgctattta gtaataactt atactgattt agctgaagag aagaaataat ttttccttca
    13921 tctaaagcta ctacagtatt ttcagattta tatttatcat taaaatagta cttcataaaa
    13981 ctctccgtat cgttaaaaca ataactccaa atctctttta tactttctat ctcttcttct
    14041 ttagcatacc taatctccat atagtctatt aagcctccct aacactgtac ttttcaacaa
    14101 atctgcaagg atgataagaa agtttagctt ttcttaatcc ttcaatacct aaatcttctt
    14161 ctctatttac aaactcaacg tccttaaatt cacttaccaa aaattgttga tttataaatg
    14221 gatacagacc tcttatatcg ggattagctt tttctatatg aatcaatgcc atatttggat
    14281 ttaaaagctc tcctatacta aaagcttcta attttccatc tacataaaca ccaaacactt
    14341 ttaccttatc ttttaatatg tcataatggt taaatatctt tttgatacct attaattcat
    14401 catccatact ttcatcaaat tcattatttt cttccttatt actttcccat tccttcatta
    14461 gtactaaaca ctcatcaaag ttttctttat ctaataattt agcttcatat ctacctgcat
    14521 actcttttaa gaaatagttt atatggtttc tcttcttttg attcttttta ccagctagag
    14581 ttcttaaact ttctgcatca taaatatagt caaataaatc tctttcttct atatactcaa
    14641 atctacctgg atatttttct tttaaaaact ctactacttc agtagtaata cctcttaagt
    14701 atattttttt attattttta gaaaaatatt caaggacaaa atctacaact tctggaagtt
    14761 tatctttttt agcaagtggt aatattgaga agctatctcc ttcgtattcc ccaactaaaa
    14821 cggcaaaatc ttcacctata taatatcctg tcttataaac atgttgccac atatataaag
    14881 tactaaaaca gtactcacaa gcttcataat ctactaaatc aaaatatggg tctaactctt
    14941 tttttgaatt tagttcaata tctttgaaaa acataaaatc ctcctacctt ttttattgct
    15001 taattttaaa aattttattt tgtatatata aaaaactcca attttattat ggtattaatt
    15061 tcatttatat tgtttaaaat ataaaatata ataagtcata tatatcttat attacccatc
    15121 ataaatttat ataaacatgt aatgaatgga gtgatttttt attgagaaat aaaatttttt
    15181 tatcaatact tattataata tcacttttaa tcggctgtga caaaaaatct ctactatcta
    15241 tacatatgat tgatgttgga caaggtgata gtattttagt tcaaacaccc acaaataaga
    15301 atatattaat tgatggaggt gatgaagata gcgaaaatat aattattagt tatcttagac
    15361 aaaaaagaat aaaaactatt gatattataa tagcaactca tccagattca gaccacatag
    15421 gaagtcttga taatattata aaaaaattta atgtaaactc catatatatg cctgaacaat
    15481 caactgatag tgaggcttat caaaatctaa taaattcttg tacggataaa aagttatcta
    15541 ttcagcatct ctataaaaat gatgttttaa acatagataa caatataaat atatatgtat
    15601 taagtccatc atatatacaa gaagaatcta atttaaattc tatagttttc aaattaactt
    15661 ttaatgataa ttctttttta tttatgggtg atgctgaaga agaaaatgaa aaagaaattt
    15721 tacattcttt taaattaaat aatattaatt ttataaaaat aggtcatcat ggaagtaatt
    15781 cttcttcatc tttagaattt ataaaaaaaa ttagtccaga tatagctgca atatcatgtg
    15841 gatataaaaa tcaatatggt catccacata gggaggttat taataatcta aaacaaaacc
    15901 atgtatcaat ttatagaaca gacagaatag gagatattgt tttttatagt gatggagaaa
    15961 ttatatttac aaaatataat tatgaaatag atacataatc taaaaaataa aactacaact
    16021 acataaaata aggtaatata aaataactag gctaaaagta tgaatataaa attgctttat
    16081 attcatgctt ctagccttca aatttgtata taaaatttat aaattaaaat atttaaaact
    16141 tattatccta atagttcatt tactattaca gatgcgatta ttaaacctcc tacagatggg
    16201 acaaatgata cactaccagg tgttactttt ctaccattca ttactttctt cttaagttct
    16261 attggttgtt cagtagaata tactactttt aactttttga tacctctatc cctaagttct
    16321 ttcctcataa ctttagctag aggacaagta cttgttttgt gtatatctgt aacgactatt
    16381 ttagttgggt ctaatttatt tcccataccc atagaactta ttattttcaa tccttttttt
    16441 tcacaagttt caattagatg tattttggaa cttaccatgt ctatcgcatc cacaacataa
    16501 tcatatcttt cagttagtat ttcgtcacta gtatctttat tataaagact tcttattttt
    16561 tttatattga tattaggatt tatatctaat attctttctt ccatgacatc aactttgtat
    16621 cttcctacag ttgaatgtag ggctggtatt tgtctattta tattagttat atctacatca
    16681 tcaaaatcta caatagtaat attgcctact ccagctcttg ctaaagcttc aacagtaaaa
    16741 ctaccaactc ctccaactcc aaatactatt atatttgaat tattaagttt ttctatccca
    16801 tcatctccaa ctagaaaact agttctcgtt gtaaaattat tttccatctt tccacactcc
    16861 tagattttta tctaaatata taatagtatt agaaaattta cattatataa tacaaaacat
    16921 tatatattat taaaaataaa ttatcttaaa ataaatttaa aaaggtatct tttaattaaa
    16981 agataccttt tacatattgg cgggaatgcg tgggaatcga acccacctaa gaggctctta
    17041 acccctcata ctagttttga agactagagg gcacaccggc acccatccac tcccataatg
    17101 aaatccttct caacgaaatc tataatatca tatattttga ctctttgcaa caatttttat
    17161 agatttatat gatagtaaat tataatttaa atagctttta tctatacatg gttaaaattt
    17221 acctgtttta ttacatatcc aaaataaaaa actggaaatt atatttttag aatctataaa
    17281 gagtttcttc tctatataat caaaatataa tttccagtaa aaatataaat tatttaacta
    17341 ttttaatata cgtatatcta tagtttttct tccccagtta taaactgttt ttgaatcatt
    17401 catgtagata tcaattttat ttccttttat tgctccacca cagtcttctg cagtaaacac
    17461 catgtcaaat tgaggtatat aaactttagt tccatatggt ataaccttag ggtctacagc
    17521 tattgttccc cacttaggtt ttgttcctgt tgcagttata ctgtgaccag tatatgcagt
    17581 tgctaccact ctcatatttt taccattgtt actactactg ctactagatg atgatgaagc
    17641 cattcttctt gaactttctc cccttgatga ggctacttgc atttctacct ttgtcccttt
    17701 gcttacaacc ttatttactg gctcagcttt aacaaccttt ttcacaaatt ccttttctac
    17761 tttctttcca ttgtgataag tttctttata tattagttca cttttaccag actttccttc
    17821 ttctttaacc ttagaatcac cctttaataa agagccatct tcaacaactg taacttcaaa
    17881 tggaatgtct ttagtttcta caactgtttt ttcctttaca tcaattactt ctattttatc
    17941 tccattagat aactttgtat tttcatctaa agttactata tcatttgcat catagctaat
    18001 gttttgagat tctaaaaggt ctcctacatt agaactaaat gttgatatag ttctttcttc
    18061 tccccttact actaatgtta cttgtttatt aagcgcagag tatcccgata atattccaac
    18121 tgataaaaca actgccatta ccgagacttt agcattactc aattttttaa aattcatata
    18181 aaatttcctc cctaagattt tttacactat atattttgct tcataaaatt ctgctttgta
    18241 agtttctttt tttatttgtg ttttttgtgt aactaaattg taactatttt ttcaagagtt
    18301 gtcaacttga caaaaaaata gaaatatgca tacatagtat tttcaacttt tcaagcatat
    18361 ttctattagt tacaacaatg tcattgttta ttgttgtttt gttatcattt tgttaccttt
    18421 tacttttata tattttctat ctgccaatta ataggttctt ttcctagctt tttcaaaatt
    18481 tcatttatct tagagaagtg tttacatcca aaaaagcctt tacttgctga caatgggctt
    18541 ggatgaggtg cttccaaaat ataatgttta cttgtatcaa tcaactctac ttttttacgt
    18601 gcattacttc cccatagtac aaaaataact gggtcttcac gctcacttaa aatagatatt
    18661 actctatcag tgaaaatttc ccatcctttg ttcttatgag aattagcttc atgcgctcta
    18721 acagtaagag cagtatttaa aagtaacact ccttggtctg cccaaggcat taaatatcca
    18781 ttattaggta taaaacaacc taaatcatct tttaattctt tatacatatt taatagagat
    18841 ggtggagttt tcacttgtgg ttgaactgaa aaagctaaac catgagcttg attatctcca
    18901 tgataagggt cttgtcctaa tattaagact tttgtgtctt tgtatgaagt gtgttttaaa
    18961 gcttcatata tattgtgcat atttgggaaa atttggcgtg ttttatattc ttctataaga
    19021 aattttctta agtttaagta gtaatctttt tcaaattctt cttttaataa ttcatcccaa
    19081 tcgtttccta agttaaccat aattatcacc aattcctttc aattattttt attattttat
    19141 ttagaaatta tatcttcttg attatcattc ttttcatttg tatttatttt tatgctcact
    19201 ctattaggta tacaaactat gctttgactt ggcttgttta taaatccagt atgtacgcaa
    19261 accttatcag ggcatgaagc atctactatc tcaacccctt tatcatgaat ctttactatg
    19321 ttataccccc ctctattctc tattttaaat tcttctttgg catttattga aacagtttta
    19381 tacaatttat tatctacata aatctcaata tttccagcat ttttagaatt tataacattt
    19441 attatcccat aacatgctgt aataacaacc aaaatgccta aaataagaag aatgtctttt
    19501 ttcttcattt tttgtcctcc tatgaaatta tgttataata aaataataac acaatttcat
    19561 aggaggaata taccatgaat aagaaaaaaa tcacatttat ttttgtgata ttgattttag
    19621 cattaatttt attttcattt tttaggagtt caagccagaa tactaaatat agtaaaacta
    19681 gctactacct tggtacagta aacgaagtta ctgtatttaa tgtaaaagaa tccaaaagtg
    19741 ataaaatctt aaatgaatgt gattcaattt taagatatat tgacaacaaa atgagcactc
    19801 atataccagg aagtgatgtt tctaaaataa atgataatgc tggtaaaaaa tttgtcagag
    19861 tttctgatga tacatttttc gtcgtaaaag aagctataca atattccaaa ttatcagatg
    19921 gatattttga cataacaatt ggtccattat caaatttatg ggctattgga acagataaag
    19981 ctaaagttcc aagtgattct gagatacaaa aacttctgcc tcttattgat tataagaaca
    20041 tcatattgga tgaaaaaaat aaatctataa aattaaccaa agaaaatatg aaaattgatt
    20101 taggtgccat agctaaagga tatgctgctg ataaaattgt agcctattta aaatcagagg
    20161 acgtaaaaaa aggtttagta aacttaggag gaaatatatt tactttagaa aatggtaaaa
    20221 atgataaacc ttttaaaata ggtattcaag accccactag taaaaatggt gaatccatag
    20281 gaaacataga aaccacaaat aaatctgttg ttacttctgg aatttatgaa agatttatcg
    20341 aaaaaaacgg aaaaatatat catcatatgt taaatccatt tacagggtat ccttttgaaa
    20401 acaatttaag tagtgttaca ataatctctg ataaatctat taattgtgat gccttatcca
    20461 cttctacatt tggacttggt cttgaaaaag gtatggattt aattaataaa attgataatg
    20521 tagatgctat attcataact aaggataaga aagtatacct aactaagggt ataaaagata
    20581 attttaaact tacagataaa tctttttcta ttgaaaaatt aaataaacaa taagtttaaa
    20641 taataattat atctattata catacaaaat acatatgaat ttaaatagtt atcatatgac
    20701 taatgcaaat ttaattttta tataaaatat ggtatatact taagtaatct aaaacaaatt
    20761 ctacttatgt atataccata ttaatagttt aaatttatat aaaatactaa ttcaaccaaa
    20821 tttttataaa gactttaaaa ataaatccat tctatttaaa gcttcaatta cattttcctt
    20881 ttgagttcct aaatttattc taacatactt ctcaccatct tttacaaaat gactcccatc
    20941 ttctaataat actcctgtat ctatagccaa tttatctgta aactcacttg cactaatacc
    21001 taatccactt atatccatcc aagctaagta agatgattcc attttcatca attttatctt
    21061 attatattta tttacccaag tttctaaaag ttcataattt gattttatat attcatttac
    21121 accacttaac cactcatgac attcattata agcggttatc aatcctatta ttccaaacac
    21181 atttggagaa gttatagaat tttgctttaa tttatttcta aatttgtccc ttatatcctt
    21241 atttataact attgaataag aagtctttaa tccaccaaga ttaaatcctt tatttggtga
    21301 tgtcaataga ataacatttt ctaaaagctc ttttccaatc ttaagtattg aattaaatgt
    21361 accataatga atatgctctg catgtacttc atctgcaacc aaaataacat tattttcttt
    21421 acatatagtt gctacccttg tcatttcttc aattgtccat atccttccag atggattatg
    21481 tggtgtacaa aacatcatta atttaggctt attttcttta atttgaactt ctaatttatc
    21541 aaaatttata taatatctat catttacaac atctaatgta ttacaaatta catttacacc
    21601 ttgttttttt gctgatgatt caaaggggtc ataaactggt gtatttaata ttatactatc
    21661 acctttctta caaaaagctt gtactacata atgaagtgtt gatacagttc cataagttaa
    21721 tgtaatccat tctttttcta catttacctc atgcatattt ttttgccaac caataactga
    21781 atcataaaat tcatcataac agtatgtata tccaaataca cctcttctta cagcttcaat
    21841 aaatttgttt tctatttctg ttggtatttt aaaatccata tcagcaatcc acattggtat
    21901 aaaatcttct ctaatatctc caaatttatc tcttataata tttaaatccc attttctaca
    21961 cttttcactt actctatctg gtttatcatc aaaattatac atttaaattt acctcttctt
    22021 ttcttattgt tataaaatat ttatctaatt tatttttagc ttacaactat taaatcctta
    22081 gtagatgtag tcaatctcat acatccatct tgtgttataa gtacatcatc ttctattctt
    22141 acgcctccaa gacttggaac atatatacca ggctctatag ttacaatcat tccttctttt
    22201 aatacttcat ttgattcagg agctaatgca ggatattcat gaaccataat tcctacacca
    22261 tgacccagat tatgaccaaa attaccagca tatccatatg aaccaattat gtctcttgca
    22321 actttatcta tctctccagt agtcattccc ggtcttaaaa cccttataca ctcttcatta
    22381 gcttttctta ctatattata tatttcttct aactctttat ttatagtacc catacaaatg
    22441 gttctggtaa tatctgaaca ataattatta tacttagcac caaagtcaaa ggtaacaaaa
    22501 tctccatact ctataacttt ttcacttgct tttccatgag gtaatgctcc tctaagccca
    22561 gatgcaacta ttgtatcgaa agattctttt tgaccaccta aatcttttat aattctaaca
    22621 atttcatttt caacttgctt ttcagtcata ccaaccttta taaagtctac tatatgataa
    22681 aatgtagcat caactatttc acaagctttt tttatatatt ttatttcgtc ttcatttttt
    22741 gtttccctta atgtagataa atcaactgat tttaaggttg cacttaactt attactcata
    22801 cttctatata aatcaaaaga tacttcattt ccctcaaatc caatttcctt tatattctgc
    22861 tctctacaaa tatcattaat tatatcaaaa tgagttctag ttttgtccat taatactaca
    22921 ttaaacaaac tagattttct tttaatttct tcaaaatatc taaaatctac tattatatat
    22981 tgtgattctt tagttataaa aacataacct gaagagctaa ataaatttcc aacataaaac
    23041 ttgtttgtag gactatttat aagaaatcca tctatatcat attctctaaa atactctctt
    23101 actttttcta tcttatccat atcttatctc caccgccttt aattaatcat ataggtaagg
    23161 ctggtaatat tgattaaaac catattacca gccaaagtta tttatagata gtaaaaatta
    23221 aatactagtc gatataatct acaacaagtt taccatcttt tattaattta tttctataga
    23281 atatatttcc tactgctatg aatatagcac caactgctat acctattata tatccaaata
    23341 agttatctac tagaggccat gcccatatag ctgactctgg gaaccattga attgctccta
    23401 gaattatacc tgtaatagct cctattacac ttccaactat gtttaaaggt ataacaaaac
    23461 ctggtctctc aagtgcaaat ggtattgctc cttcagatat acccataaat gataagaata
    23521 tagaagtttt tcctgcttga tagaattgtc tatcatatac tcttcttcct actaatcttt
    23581 tatctaataa tgttgttaat cctagtccaa ttggaggaac aactatagct attgttcttg
    23641 ctgttattgg aagtacattc tctgtagtta aaccaagtgc aacgaatcct gctgctttat
    23701 ttattggtcc tcctaagtcg aatgctgtag ctgctgccaa agctgttgca tatacatatt
    23761 ctccagctgc tcctgctgct gttaagaagt ttttcatact ttcattaatt aatccaccaa
    23821 atggagttat tataaatatc atcaatacca tacaagctaa tgacgctatt aatggtatta
    23881 aaaatgttgt tttaaaagct aaccagttat gagaaacttt tatagattta tttaaccatt
    23941 ttacaaaata tcctattata aatgctatta gtattgcacc taaaaatcct gatgcaactg
    24001 gaacaacttc agtccattgt ccatcaacga attgtggtac acctacaggt ttattagcta
    24061 tatatccacc tataaatcct gcaattaaag ctgtttttcc acctatagag tttgcacaaa
    24121 atgctgcaaa cagtggtatt gcaaatccaa acaaagtaaa tccgaaattt gacattaatt
    24181 gtgctatatt taaaagacta agcttgaacc ctgtaaattc tcctgagttc atagcatcaa
    24241 ctatacctac agatgggtca agtcctaata tagcatatgg tattaattga gataaggccc
    24301 ctataagtcc acccattact aaaactggta tcatatatga tatacctgtc attatatgtt
    24361 tacttatttc tttccatttt ccatttccct ttgattgagt tggactagat ggagtagatt
    24421 ttcctacatt atttcctcct gttgtagaag cacctgaact gtttataact tttttcttaa
    24481 ttgccattct atttcctcca caataaattt attatattcc taaatcttct tctatttctt
    24541 ttataacacc ttctgcattt tttatagctt cttgtaattc aacttcataa acttcacaac
    24601 catcaaatct ttccatacct tctggtgtta ttgctactgc atgtattatc atagttgctc
    24661 ctaatatatc atctcttgtt aactcatttt gtacaccatc agcaccttga gtttcaactt
    24721 ttgcttcata acctaatgcc tttgctgctt gctctattgc ttctgctgcc atgaaagtgt
    24781 gagctagtcc cattggacaa gcacataatg ctactaattt tttattcatt tcaaattcct
    24841 cctattttta gttaattatt tttttatttt ataaccttag tgtttaatta taaacctaaa
    24901 gcttcattta ttaagttaga tatttcttca acattatcac tttttaaaag agaatcttta
    24961 aattctttat ttattaattt tcttgaaaga gatgataata atttaagatg aatattctct
    25021 ttactttttc ctggcataag taagcttatt gctaatttaa ccttatcctc accttcattc
    25081 caaacaacat cttcattaaa cttcaatact actactgctg gattttcaat tgcatcattt
    25141 ttagtgtgag gtattgctat agattctcct aaatttgtag taaattgttc ttctctagcc
    25201 attaaacctt catatactaa tctctcatct tctgccaagt ttaagtcttt agcttttttt
    25261 gatataaatt ttaaaacttc aacctttgac ttagcatcaa catttaaaaa tacatattct
    25321 ttgttaaata tgtttgttcc cattattaat ttcctcctta attacctatc agtgccatta
    25381 atttattaaa gtcacatatt ttaataattc ctcttactcc gccttcatct tttataaaat
    25441 tataaaggta tttaaatatc gagaaattat gtttttcttt agtattaaaa aataccataa
    25501 atactagctg aacctcttgc ttatcccaaa ttattggatt ttcaagtatt ccaactccta
    25561 ttatagattt tttatctccc ttcactattg tgtggggtat tgctactaga tttcctattt
    25621 cagttgatga aatattttct ctatctatta tactttttat agaactttcc tctataaaat
    25681 ctctttcttt tagtttattt gaaagtgaaa ttatgacctc ttctttagta ctagccttta
    25741 tactgaaaaa agctttttca tcaaacatgt tacttattat ctttcttctt tcttcctttt
    25801 cataaaaggc tttgtttacg ttttcaatta agctatcatc aaatatattt tctatatata
    25861 agacaggttt ttcatatcct tttaattcaa cggtagatac tatcaaatca acatcttgac
    25921 ttatagccat atcgagatat ctaactggat aaacacctac aacacttaaa tcacttatat
    25981 tctgttttag cttttcagaa ataagttgtc ctgttcctat cccataatga caaactatac
    26041 aaattttctt actagtattt tttttcattc tttcatttga agcagcaaag tggatagcta
    26101 tatatccaag ctcatcttca tcaagtttta aattaaactc agtttctagt ttatttgata
    26161 aaaacacggc taaattaaaa gctataggaa acttctcttt tatttgatga agtaaaggat
    26221 tatttgattt tacattagct ctagctctat ttaaaaatct ctttatatgg tcagagattg
    26281 caaccataaa ctcatcatct tttgtataat cactacctga aataaggaat atatcttgaa
    26341 gtgcactact tataacacta cttattcgtt cctcaatttc acttgtgttt tttcttcctt
    26401 gtgtaccttt ataggctatt acaccagaat aatttgaaat ataaattact tcatcttcaa
    26461 taagtttaaa tccaatttta tcagatattt ctttcattag attttctata aagtagtagt
    26521 tatgaaatct ataacttgta tccattaagt ttatattgtt actatgacct ctcttactcc
    26581 taaatacaga aacgattatt tttgaaagca aaagattaaa atctttatct gaaattattg
    26641 tatctttttc tcttaagtgc ttttctaaaa tactttctat acagtgtata tcgttttcac
    26701 taatgtcatc taaaaacacc ttcactttac ttttttcatc taattttatt gcatagtcag
    26761 taattaattg ccttatatta atttcttcac catgtatata gcttccatag taaggtttag
    26821 attttataac taagtcatac ttttcaagtt ttcttttaag cttactagac aatttattta
    26881 tagcggctat acttagattt aattcttctg ccattgcttc tatactcata taatttctat
    26941 taataagcat acatattata tttgacattc ttgactcttc agagtcatct aaaaaaccat
    27001 caatatattt atttgcttct ttaatagctc tggctatatt gtttttagaa ccgcttaact
    27061 tgtatcctat acctctagaa gaagctatta ccaaatcata cttgcttaaa acactattta
    27121 aatctgctat atatctttta atagttttag tagacacatc caatttgata gctaattcgt
    27181 ttgatgtcat atatccatct ttattgctta aactctttac tattattgca tgtttcttag
    27241 ttatcattgt atcaccttct ctttgatttc aattatatat caagtaaaat tttaattgta
    27301 tatataatat gtctatataa gggacatttt gtatttatat tttattacat aatgtaatta
    27361 ttgcctctgc atatatacct attgcagtta taaatctatc taagctagca aattcattcg
    27421 cactatggac attgccaaag ctaccatcag gaaattcaca accaaatatt actgaattat
    27481 tcatttcaga agcataactt cctgcactag ttactctaac atcatttttt aaatctccag
    27541 aatactttat atatatatca tgcaaacttc ttacaagttt tgaatttcta tctatataat
    27601 ttgcttgctt taaattttcc ccaataagct caaatttatt aatattattt tgctccatat
    27661 acaaattaaa tttttttatt atatcttcaa tggttaatat ttctggatat ctaacgctta
    27721 aaactacttc taattttcca tctactatat ttattattgt tggcaccatt gataaaatcc
    27781 cacatttccc ctcaatattt aaaccaaata agtttccatt tatattatct tgatttatca
    27841 acttatataa atcttttgtc catttttcat caatattttc tgacaaaagt ttaattgtag
    27901 ctaatatagg atttattgat ttttcgggtt tagatgaatg accacctttt ccatacacaa
    27961 tataattgcc attatcataa tttatcgata tattgttaat atcaaaacat atattatctt
    28021 tacccaattt ttctacattc tttatataaa ctttatctgg tattgtatta aactctattc
    28081 caccacttat atataaagat ttatcgtcta tatttgaaat taactttatt attgctccac
    28141 ctttttctcc atttaataca ggaaatttag catctggagt aaatccacat acaccatatg
    28201 gctctttgct ataataatgc tttatacatt taaatccact ctcttcattt cccccagcta
    28261 ttaatctaac ctttcttttt aaattaatat ctaaatcctt tatcattttt agtgctaaaa
    28321 aattcactat cataggccct ttattatcag atacacctct agcaactaat ttatcaccta
    28381 taatatttag tttaaatggt tcactatccc atccttcacc tggatttaca acatcacaat
    28441 gtccaaatat atctacatac tctttaccat ttccatattc aatttgaaca gcatgattat
    28501 ctatattttt tactttgaaa ttgttttctc tacctagatt ttcaaaccag tttaatgcat
    28561 catatactcc ttttccaaaa ggcatgtctt tagatacagt ttttctatca taaaatgaag
    28621 gtatactaac ccattgctcc aataatttta aaaattcttt tttatatttt ttgctttctg
    28681 ccttaaacaa ctccataatt atcactccaa tttagaactt tatattatat atcatagttt
    28741 atcttattta ataactcctt atactttatg tcatttcaag ggacaaaact tttttactat
    28801 tgattttata atctatttat atataattat ttgtaggata aatttaatat cataggagga
    28861 acaggattat ggaaccatta tttttaaaac ctatttttat ggatagaata tggggtggta
    28921 ctgcacttaa agataaattt aattatgaaa tagattcgcc aacaactggt gaatgttggg
    28981 ctataagctc tcataaaaat ggagattgct taatagaaaa tggaaaatat aaaggtaaaa
    29041 aactatctga attgtggaat aaaaatagag aattatttgg aaacacacct ggtgataagt
    29101 ttcctttact tacaaaaata ttggatgcaa atgataattt atcagttcaa gttcatccaa
    29161 atgatgaata tgctaaaaaa aatgaaaatg gagagctagg taagacagag tgttggtatg
    29221 taatagattg ttctgatgat gcagaaatta taataggtca taatgcaaaa tctcataaag
    29281 aatttgtaaa tatggtaaat aataatgaat gggacaaact acttagaaag gttaacataa
    29341 aaaagggaga ctttttctat gttccaagtg gtactataca tgctatatgc aaaggaacat
    29401 tgattttaga aactcaacaa aactcagata ctacttatag agtctatgat tatgatagaa
    29461 ctgacaattc aggtaataag cgtgaacttc atgttcaaaa atcaatagat gttacgaatg
    29521 ttcctcatat aaatttcgat actgactata aaatcgtatc aacatcagac tttaaatgca
    29581 caacatttgt gtcaaacgaa ttttttagtg tttataaatt agatgttttt ggaaaatgta
    29641 attttacaca caatacacct ttttctttat acagtgtgtt ggatggaaat ggaaaactta
    29701 tacacaattc tgtagaatat aatttaaaaa agggtatgca ttttatacta ccaaacgact
    29761 ttggagattt tagttttgaa ggtaatttag agattatatg ttctcacata tagatataaa
    29821 acctagctaa aaataggcta tcataataat ttaccttatg atagcctatt tcttacaact
    29881 taaatattta aacaaatagt atttttattt tatttttgct cataatcatt tttaatagta
    29941 tatatcagaa aattctattt ttattttttc ttgaatatta tatattctct tatcttctgt
    30001 gtaatgttca ctactaaatc ccttcattgg aagtgaaatt aagaactctg tgcctttatt
    30061 cacttcactt actacttcta tatctccacc atgaagactt actagattct taactatagc
    30121 aagccctatt ccacttcctt cagtatttct ggataaagtc ttatcaactt gtgaaaattc
    30181 ttcaaaaatc aattctaatt tatcttgtgg tattccaact ccagtgtctt ttacacttat
    30241 gattacttta tctattttat aatgaatact tacatatatc cagcctccat tatcagtaaa
    30301 cttaatacag tttgacaata gattcaacat aattctctca atttcaacct tgtctatata
    30361 aacattaatt tcttcaaggt ctgtatcaaa aagaattttt atgtcttttc taagtgcata
    30421 ctcttctata ttcataaata agtcttctat tacagataca atattgtatt tcgcaagttt
    30481 tagtgtatag aacccagact ccatctttgt taaatctata atgttattta ttaatctttg
    30541 aagcctataa gaactttgtc taactaaatc cacatgagat ttaatattgt tattgtaatc
    30601 ttttatcttt tcatttctat agaaagaatc taccagttga tttgaactag atataacatt
    30661 tagtggagtt tttaattcat gagacatatt tgcaaaaaac tccgttttga ttttatctgt
    30721 tttaaatctt tcaagcagtt ctttttctgc ttgctcggaa tatttcttat gtactaaatc
    30781 ttttataata agcattatgt atctagtatt gtatatagca aaaggtaatg cacttaattc
    30841 tacttctact atatcatcat aactatttat caattcatat tccagtaaaa gtatacttct
    30901 attttcattt aaaactttag ccatattatc cgtaaatttc attttttctt cagtattcgc
    30961 attcattaat agtttaatat tagaatcttt tatatcatct atgtttgtaa aagctagcat
    31021 atctaaaaac gacttatttg catagtttat acttaaatct tcttttaata agcatatgcc
    31081 atcaggtaat atatctataa atcttgaata tgatgattga ctttcctcaa gttttatttg
    31141 agatattttt cgagaggttg tatcacgtat tacaataata gttttattag taccagcatt
    31201 agtatactga gaaaaactca tctctacata ctttacttca ccatctatta catatctttt
    31261 ttctatactt tcttcacttt tacatactaa tgaaaaatca atactctcta aattattttt
    31321 aaaaatttcc ctacatgcat tattaacata tattttgtta ttaccttcaa gcactactat
    31381 gccatctcca atactttcta aaaaatcttt acttctctta tttgcttcaa taagtttgcg
    31441 ttcgtactcc tttttcttag tcttatcttc tagtacacac aatactcctt ctgtttgtga
    31501 agcaataatt aaaggtgcaa atatagcttg ataaacttta ttatcgcttg tactaataag
    31561 tttctctgca ttcttctcat gaacaaacac ataatgaatg ctttctatca aatcattgaa
    31621 gttttttatt ttatcagtca atttatcttg ttctttatag tctccaaaag tatttctaaa
    31681 gctcttattt gcatatgtaa tttctccatc tttgctaaat actactatgc tatttactgc
    31741 tacatctaat gtagattgta gcctagattc tcttttcata agtattccct taagttcctc
    31801 tatcttttct gtctcataga ttaatttttt attcttttct tttaaacttt ccgttttttt
    31861 tgttaattct tcattcgtat catgcaattc cagtgctgtt ttcttaatat tcttagatac
    31921 tatgtaatta tataaataat ataaggctac atttattatt atctgggata atatcctctc
    31981 tacatttcta ttatcaataa ctatatgcaa tagatttgga actcttgata agattattat
    32041 tactattatt ctgttaaaaa tctttttttc atcatattcc catttgcctt tatttgaact
    32101 tgaatttaat tcaattccac taacaataga aataattatt atgaatatag atattataac
    32161 tcctaaagca tattgtgatt taccatttcc cagatagtca caaattcctg atattatgaa
    32221 taaagatgtt attgttaatg tagcagttgc tataaataaa attacacttg aataaatttg
    32281 tttgttatcc ttaacaaatt taaaacttaa gtatacaccc agtataggaa ataaatctgt
    32341 tattgctgat attgtgatgt taatctccat tatagactta gttttaatcc ccaaggaatt
    32401 aaataaatat atacactcca atactccagt agctataaaa attaatccta aaaatgtaga
    32461 aaatgaatct actttaaatt ttgtagtatt aaatataatt actcctgtag ctactaaaaa
    32521 tatcgtatat atggcatgta ataaagtttc atatttctct atatctttta taataaataa
    32581 taaaagtact gagcccatta ttataaataa aaggctcatg tcttctcttt cttttatatc
    32641 tggttttaca tcaggtatta tattcttcaa tactttacac ttcctcttaa ttaatatttt
    32701 atactaatta attatacgat actcgacatt ataattcctt ctttatacct taaagcaaaa
    32761 acagacattt tctgctaaaa caaaattctt ttgttttcta ctcttttagt tattttgttt
    32821 ctatcgaagt tttccaatat aatcatgcaa ttctttctgc tagaatcaat caaatctctg
    32881 tattctccta atgttatttc tttattttct tttatataat ttatcaaaat gttctttgca
    32941 ttttcataaa tatctttgtc cattatatac aaatcatcta atttctctac tttattacct
    33001 atcattgact ccaatacttc agcatagtta tgatttcctt cagaaacttc atctattgtc
    33061 agtatagaag aaactccaca tgattttaat cttttttcta ttttttttgc tatttctttt
    33121 tgcttatcat ttaaaataac ctcaaaatct aatagagata ctatattatt ttctattttt
    33181 atagcatttt ctgtagacaa tttttctaat aaaatatcca tctccctagt cttaaaatta
    33241 ctctctatct tagaccttac ttcttctttt agtatccctt ttctaagcct atacttctta
    33301 tggtactcac ttaaaagctt tattgtattt tcttttaatt tattgtattg atttatatgc
    33361 atatacatat ttcctataat aaatacttta tcttctgata taagtgtttc aagcgctctt
    33421 tttacatctt cttcatgagc accactatag ctcattattt cttttatatt tggataattt
    33481 tttaaattcc tttttaagta ctcttctatt atatctttta gttcgccttt ttcttttatt
    33541 tttaatgctt ctataacttt ttcatcaaat ttcttatgtt ttttaggaga tgggtcaatt
    33601 attacacctc cacctatagt ttccattgga gaataacgtc tcactacaaa cgtatcacct
    33661 ttcttagata ctatgttttc ttcaagtctc aactgaacat agccactttc tccactttca
    33721 attaattcct tatctagtgg aactgctcta caaagtatct ctctagttcc atgatacaat
    33781 cttaatctat cccagtgctt taatccttta tctaaatgat ttaccaatga taattttaca
    33841 tctaacatca ttgattcctc caatgagttt ggtgcagcta aaacatctcc tctttttata
    33901 tcatccactt ttacatttga tatattgatt gctgttcttt gacctgcata agctgtatct
    33961 ttattttctc catgaacttg tatacttctt atttttgttt ttaatacctg tggatatata
    34021 accaaatcat cttctatact tatctttcct tctattaaag tgcctgttat tacagtacca
    34081 aaccctttta ttgaaaatac tctgtctata ttaagtcttg ctggagaatt ttcattttta
    34141 tcttctatat catcactcat tttatctatt ttttcaataa gagtgtctat acctctttta
    34201 gatatagaat caacttcaat tatttcagca tcttcaagaa aagttccttt tattttttca
    34261 caaatatctt cttttactag ctctctaaat tcatcatcta cagtatcaga cttagttaga
    34321 accactattc catttttgat atttaaaaag cttagaatat ctaaatgctc aactgtctgt
    34381 ggcataactc cttcatctgc tgctacaaca agtaaaacta tatcaattcc tgatgctcca
    34441 gctaacatgt tttttataaa tttttcgtgt cctgggacat caacaattcc agctcttcta
    34501 ttgtttggta aatcaaaata agtaaatcct aagtttattg aaatacctct ctttttttct
    34561 tcatctaatg tatcagtctc tcttccagtc aatgctttta taagagtagt ttttccgtgg
    34621 tcaatatgac ctgctgttcc aattactaca tttttcattt tttgccccct ctaaacctgc
    34681 tatgactaaa gtcacaagtg tgtgtagcta ttttttaatt aaaacttcat acttatactt
    34741 ctaaatttaa tatttattaa ctcaaattta tttaattaaa tgcttttctc aattcctcaa
    34801 ctattacatc aaattcatca tcaaatatag ttcttacatc tagtacatat ttattatcat
    34861 acactctggc tattatatgt gcttcactaa gtcttagttt tttttctaaa gatgaaacat
    34921 tcatatgttc aggagttatt gatattacct ttgtacttat agtttcaaga ggcatagacc
    34981 ctcctcccac ctgtgaaaat ccatcttcta tatttatgtt tgcatttaag tttaaagcag
    35041 ttattttttc aaatagttta tttgctttta cttctaattc ttcaatttta tatgtcaaca
    35101 tttttaaagt aggtatattt tctatagctt ttgtctcatc taaatacatt ctcaatgttg
    35161 cttcaagagc acatattgta agcttatcaa ctctaagtgc tctagtaagt tgatttttct
    35221 tcattttttc tatatactct tttttcccaa ctataatacc tgcttgtgga cctccaagca
    35281 tcttatctcc actaaaagtt actacatctg caccttgtcg aatagaatcc aatacagttg
    35341 gttcataaga taaaccatat tttgataaat ctataaaaac tccacttcct aagtcttcta
    35401 ttacaggtag tttatatttt ttacctaaat taaccaattc ttctatagaa acactctctg
    35461 tgaatcccat tattctataa ttacttgtat gaaccttcat caatacattt gtatcttctg
    35521 taatggcctc cttgtaatct ttcaaatgag ttttattagt tgaaccaact tcaactaatt
    35581 ctgcaccact aagagccatt atacttggaa tcctaaatga accacctact tcaactaatt
    35641 ctccacgaga tacaattgct tctcctcctt tagccattgt gctaagtaca agaagtactg
    35701 ccgctgcatt attatttaca actagtacat cttctgctcc agtaagtctt tttattgtac
    35761 tagttaaatg agagtatctt gaacctcttt ctccattatc caaatcgtat tctaagtttg
    35821 aataccttga agcagcacac cataattcat cttttatatc ttcactaagt aaagaccttc
    35881 ctaaatttgt atgaataact gtaccagttg catttataac tttttttaaa gataatgagt
    35941 aatttaactt aactctctct attgcagatt ctattatttc accaaactct attgttacag
    36001 agtttgatgc atcttctttt aatcttaata taaattgtct ttttaaatct attacttctc
    36061 tcacagattc taaaactaaa cttctaggat attcatttat tatttctaca attctattat
    36121 cacttaatac ttcatcaact gaaggcaaca ttgcaaacaa ttctcttttg ctcaaaacaa
    36181 tcactctttc tctataatat tttataaaac tgtaatatat ttttcccctt ttggaactac
    36241 agaacctata attttagctt ctattgctcc atttaatttc atatctttta caagttcctc
    36301 tgcaagttct tcttttactg aaattaacaa ccctcctgat gtttgtgggt cgtataaaat
    36361 atcttgaact gcaacttcta tatttcctac aacttctaca tctttagata cataatgcat
    36421 atttttatac ataccagcag gtataattcc catttgtgcc atttctattg caccttcaat
    36481 aattggtaca tgttttgatt caatttcaat acttacttca gaagctttgg ccatttctaa
    36541 agtatgacca agtagaccaa aaccagttat atctgtaacc gaatttacat caaatttctc
    36601 aaaactcatt gctgcatatt tatttaaatg tatcattatt tctattactt tatctgctat
    36661 atgttgttct accatacctt ctttcatggc tgtatttaat acacccactc caattggttt
    36721 tgttataatt aacttatcac caggttttgc agtagcattt gataaaactt tatttggact
    36781 tacaatccca gaaactgaaa gaccatattt aggctctttg tcatctacag tatgccctcc
    36841 aaccaaaagt gctccacttt ctttcacttt atcaaaccca ccttttaata tttctgcaag
    36901 tacatccata tcatggcatg atggaaaaca aacaatattc atagcaacca aaggtttgcc
    36961 tcccatagca tatacatctg atagtgaatt tgatgcagca atttgaccaa atacgtatgg
    37021 gtcatctacc attggtgtaa agaagtctaa agtttggata agtgccatat catcatttaa
    37081 tttataaact gcagcatcat ctgctgtatc tagtcctact aataaatttt ctatattatc
    37141 atttttaggc aattgagata aaactgatgc cagaacctct ggccctattt tagcggctca
    37201 accacctgct gttgtcatct ctgtaagttt tttttgttct tttttcataa aagtgcctcc
    37261 tttactaaat ttccacatgt acacacatat acatacatat ttataataac atatctatat
    37321 gtaagttttg tattatattt tagtctacac aaattaaatc ttttatattt tcatactttt
    37381 tatctccaat accatttaca ttttttattt cctcaattga actaaactgt ccattttctt
    37441 ctctgtgttg taaaatttta ttggctgtag cttctccaac cccaggtaga gaatccaact
    37501 cttctatagt cgctacattt atatttactt ttgattcgtt agatatattt ttattggatt
    37561 tatttttagg ctcacctctt gactcattct tctgatttgg tttattggaa tcatcattac
    37621 ttgtaacaga tgttgcttca cctattttag gtattatgta atgttgttca tcttctaatc
    37681 ttactgatag attgactcca tttaaatctg cttcttttgt cgttcctcct agtaattcta
    37741 cagcatcata aagtctcttg tctgactcta tagttacaat tccaggtcta tttactgctc
    37801 cacttatgta tatagttatt ttattatttt gaaaattttt atctatgtct ttagttactt
    37861 tattgtgatt attatcttca cctttaattt cattctctac aacatgtgtt ttttcattag
    37921 gtaaattttt tttacttaca acataaatat catctttgaa aataagcgat ttataaacga
    37981 ttattgatga tattattaaa ataaataaaa caaaaaacga aataaatttt accttttttt
    38041 tcatatatta atcactcctt tcttttaatt attgacaaat atatgctata ctaaaagatg
    38101 aatttaaaat ttggaggctc acaatgaaaa gaaatttatc acttttatta atctgtttat
    38161 tgatatttac ttcattttta ggaagctcta atatctcttt tgcagataat gaaccagcta
    38221 tagttgctaa acatgcagtt ttaatggact atgagtctgg caaaatacta tataataagg
    38281 atggaaattc taagctttat ccagcttcaa caactaaagt atggacagct tgtttagttc
    38341 taaaggaggt taaagattta aatcaagtaa tagaaattaa agatttacct caaatagatg
    38401 gctctagtat gtatctaaaa aatggggaat cttttactgt aaagcagtta ctagatgctc
    38461 ttttggttca ttctgctaat gatgctgctt ttgtattagc tagatatgtt ggtggtggca
    38521 atgtacaaaa atttattgac ctcatgaact ctgaggcaaa aaaaattgga gctactaata
    38581 ctcattttaa taatcctcat ggattaccag acccaaatca ctacacaaca gctcatgata
    38641 tggctctcat agctagagaa gctatgaata atgatacttt tagacaaatt gtaaaaacta
    38701 agtcacttaa atttgaagct acaaaagcat atccttatga gagatacttt gtaaacacta
    38761 ataagttttt gacatcacat gataagatta catacaaagg tcaacctata aatataaaat
    38821 atgatatagt tgatggtata aaaactggat atactgatgc tgctggtaaa tgtcttttat
    38881 cgagtgctgt aaaagatggc agaagagtta tcgttgctgt atttaattca actaatgctg
    38941 atttatattt agactcacgt attctgattg attatggatt tgataacttt aagtgtgcta
    39001 ctattgttga taaagaaaaa tacacagata ctaaaaaagt attgtttaca aaacaacatg
    39061 aattgattta tgaaccaaaa aatagttata ggatattctt agaaaaagat gaatctcaag
    39121 gcaattatga taccaaaaca gagttaaata aaattgattt gcctataaaa aaaggagcta
    39181 aggttggtac tttaaatgta tataataatg gtaaactaga aaacagtata gacttaattg
    39241 caaaaaataa tcttgatagc agtcttccat ttttgactga aaataatgtt ttaatgactt
    39301 ttgttaagat tattgcaggt attctagtgc ttttagtttt atttataata gcttcaaata
    39361 taaagaagaa aaaaagaaaa aaagctagaa gtaaaaaaaa tatgaaaaag taacaagtag
    39421 ttagaaatta taataaaaaa tttataatat acttatcctt ataaatctaa aagtactgag
    39481 ataataatta taactattat ctcagtactt ttaattttat gtttatgtat tttttatacc
    39541 tatatatttt tttgtttttg tttgtcttta agcttacatt ttgaacaatt tcccagacat
    39601 tcatcaacca tatctagaca ttcattaaat gctaccttac tactattttt atgccttacg
    39661 attaatatat cttgtttttt agcttgagac tcaaccgttc tagacatctt atgtgaaaca
    39721 gttgatgtaa gtatgacaac tgcatctggt cttcctatag aattatttaa tttagatgac
    39781 atggtagtat atacctttgt cttataacct tttttcttgg ccataaccat ataatctttt
    39841 tccattcttt catgaccacc aatcactaat aagttcatta gatttcctcc catttatttg
    39901 atattgattt tcatt
//
LOCUS       DAEPUT010000036        38697 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.037, whole genome shotgun sequence.
ACCESSION   DAEPUT010000036 DAEPUT010000000
VERSION     DAEPUT010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38697
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.037"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(84..695)
                     /locus_tag="KRL22_001944"
     CDS             complement(84..695)
                     /locus_tag="KRL22_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1272435.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(787..1776)
                     /locus_tag="KRL22_001945"
     CDS             complement(787..1776)
                     /locus_tag="KRL22_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBH1272436.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAINNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(1843..2706)
                     /locus_tag="KRL22_001946"
     CDS             complement(1843..2706)
                     /locus_tag="KRL22_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HBH1272437.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(2812..3408)
                     /locus_tag="KRL22_001947"
     CDS             complement(2812..3408)
                     /locus_tag="KRL22_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HBH1272438.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(3448..4251)
                     /locus_tag="KRL22_001948"
     CDS             complement(3448..4251)
                     /locus_tag="KRL22_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBH1272439.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(4287..4727)
                     /locus_tag="KRL22_001949"
     CDS             complement(4287..4727)
                     /locus_tag="KRL22_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBH1272440.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(4740..6842)
                     /locus_tag="KRL22_001950"
     CDS             complement(4740..6842)
                     /locus_tag="KRL22_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBH1272441.1"
                     /translation="MRKMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCMSSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(7103..8806)
                     /locus_tag="KRL22_001951"
     CDS             complement(7103..8806)
                     /locus_tag="KRL22_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HBH1272442.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(8832..9791)
                     /locus_tag="KRL22_001952"
     CDS             complement(8832..9791)
                     /locus_tag="KRL22_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1272443.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(9927..10445)
                     /locus_tag="KRL22_001953"
     CDS             complement(9927..10445)
                     /locus_tag="KRL22_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HBH1272444.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(10488..10973)
                     /locus_tag="KRL22_001954"
     CDS             complement(10488..10973)
                     /locus_tag="KRL22_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HBH1272445.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(10970..11587)
                     /locus_tag="KRL22_001955"
     CDS             complement(10970..11587)
                     /locus_tag="KRL22_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HBH1272446.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNTITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVLMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(11652..12014)
                     /locus_tag="KRL22_001956"
     CDS             complement(11652..12014)
                     /locus_tag="KRL22_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH1272447.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            complement(12758..13255)
                     /locus_tag="KRL22_001957"
     CDS             complement(12758..13255)
                     /locus_tag="KRL22_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBH1272448.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFKFWQMDFDRTYISDFEEYQCNTFDTKKQEVHI
                     YIGIK"
     gene            complement(13430..14341)
                     /locus_tag="KRL22_001958"
     CDS             complement(13430..14341)
                     /locus_tag="KRL22_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH1272449.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            15265..16116
                     /locus_tag="KRL22_001959"
     CDS             15265..16116
                     /locus_tag="KRL22_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH1272450.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            16120..16590
                     /locus_tag="KRL22_001960"
     CDS             16120..16590
                     /locus_tag="KRL22_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272451.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            16603..17913
                     /locus_tag="KRL22_001961"
     CDS             16603..17913
                     /locus_tag="KRL22_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1272452.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKKEYLTFLEKHDKTL"
     gene            18125..18871
                     /locus_tag="KRL22_001962"
     CDS             18125..18871
                     /locus_tag="KRL22_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1272453.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIKKELNGKIIDTPGHTADSI
                     SLLIDDGVLFCGDSAMNGFPSTHKITIFTESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            19233..20774
                     /locus_tag="KRL22_001963"
     CDS             19233..20774
                     /locus_tag="KRL22_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH1272454.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            20809..21915
                     /locus_tag="KRL22_001964"
     CDS             20809..21915
                     /locus_tag="KRL22_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1272455.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(22268..23554)
                     /locus_tag="KRL22_001965"
     CDS             complement(22268..23554)
                     /locus_tag="KRL22_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1272456.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(23677..26775)
                     /locus_tag="KRL22_001966"
     CDS             complement(23677..26775)
                     /locus_tag="KRL22_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH1272457.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRTKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKYLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            27479..27637
                     /locus_tag="KRL22_001967"
     CDS             27479..27637
                     /locus_tag="KRL22_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272458.1"
                     /translation="MKIFSFLLFVIGICLCIAGFIGHYPVFVGTTLSFLAIAMIAVRQ
                     VKTKKKMK"
     gene            complement(27924..28628)
                     /locus_tag="KRL22_001968"
     CDS             complement(27924..28628)
                     /locus_tag="KRL22_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1272459.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(28619..30226)
                     /locus_tag="KRL22_001969"
     CDS             complement(28619..30226)
                     /locus_tag="KRL22_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HBH1272460.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(30480..31658)
                     /locus_tag="KRL22_001970"
     CDS             complement(30480..31658)
                     /locus_tag="KRL22_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272461.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(31884..32378)
                     /locus_tag="KRL22_001971"
     CDS             complement(31884..32378)
                     /locus_tag="KRL22_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1272462.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(32379..33140)
                     /locus_tag="KRL22_001972"
     CDS             complement(32379..33140)
                     /locus_tag="KRL22_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1272463.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            33842..36676
                     /locus_tag="KRL22_001973"
     CDS             33842..36676
                     /locus_tag="KRL22_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1272464.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNTDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            36719..37963
                     /locus_tag="KRL22_001974"
     CDS             36719..37963
                     /locus_tag="KRL22_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1272465.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLDIKNSVCFKA"
     gene            complement(38458..>38697)
                     /locus_tag="KRL22_001975"
     CDS             complement(38458..>38697)
                     /locus_tag="KRL22_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272466.1"
                     /translation="EGNRSANTITITVSGTASQAVQTDLDNVSVLVKAGAVSETTATD
                     SAANVTFEVKKHVSDPISTIGKISSGLSSLFNILK"
BASE COUNT        13002 a         6452 c         4483 g        14760 t
ORIGIN      
        1 atttatactt tgaaaataaa ataaactatc ttccaaacat tttattatat gcttaaaaga
       61 tagttttgtg tctttaaaat aaattaaatt gtatatattc cttcacataa cttttgtata
      121 ttactaggtg gttgccattt accatctttt ttagtatatg taatcatagt tgtaacttcc
      181 ttagttggtt tcttattgta aaggtctata atcatttttg tcatatcatc ttgaacttct
      241 ttttcttttt tatcgtaatt cttttcatca gttacataag attttactaa agtgttcgct
      301 tcactcatta ctttactagt atctaaagct ttacttacaa ctttcaaagt tatcttatcc
      361 ttactagaag attccactgt tactgtcttt tcaacacctt gaattaattt aacaattgtt
      421 tcgtatatct tttcagcatt ttctttacca taaagaggtg tcaattgagc aatcattgaa
      481 accttgtcct tgctgttata agtttgaatc tgtttatatt cagcttctgt taatgcatca
      541 gaaattcctt tttcatcata cttatacatt tctaatgcag ctaaattagc ttcaaaattc
      601 gactttactt tttcttctgc attagaacac cctatagtta gaactaaaac tagagccata
      661 atcgtagata atattaactt ttttaccatt ttcatacaaa catcctccct caattaaaat
      721 aataaaaaat ttatttatca acattataac ataaatttgt ctaactatag aattattttg
      781 aatattttac cacttccagt ctattccaat accgttttct tttgctttat cgtatattct
      841 ttttgctgtt acgacatctt gtacacctat cccaacagtt ttaaatacaa ttatctcatc
      901 atcatcttct cttccaggaa tagttccgtt tataacattc cctaaatcac cactaaaatc
      961 atctttactt atcttacctt cttttaatgg aattaatata tctcctgact cagataaaac
     1021 tgcatctgtt gattcaaaaa atatcttaga cgctctagtt aaacagtttg ggcacaactc
     1081 ttgcatatct ggcatatatg aacctactgc acttattaaa gctccttttt tcactaagtt
     1141 tccattaagt actggttgtt ttgatggagt agctaaaact atcacatctg cgttatttat
     1201 ggcttcatca gatgattcaa ctgcaactat tttagtatta tatttactta attttaagtt
     1261 catttcttct gcaaattttt ctctactttc cttgtttcta ctaaaaactc ttacctcatc
     1321 caaatttcta gcttctatca tggcttcaag ttgtggctca ccttgtcctc ctagacctat
     1381 caaagctcca atcttagaat cttttttagc caatacgtct atagctgctc cagaggctgc
     1441 tccagtacga atctgagtta cataagtacc atccaatact gcactaactt ctccagtttc
     1501 tccatctaat aatagtactg ttgctggaat tactggtttg cctttttgag catttttagg
     1561 aaatacagat acaattttta ttcccccaca gcctaattct tccacatatc ctggcataaa
     1621 taacatacta gcatcttgac ttggaacaga tatattggtt ctcaaaggat ttacactctt
     1681 tccttcacaa taaattctaa aagcttcctt atcagcttca attgcatctc tcattgtaaa
     1741 tacttttttt atgtcgtctt tttttaaaag tagcattttt atacccccaa ttttaataag
     1801 tctctatgct aaatattata gcataacatt taatttaatc ttctatttca aatcaaataa
     1861 atctacatac tctggtttta gcatagaact tatcaacgct ttatttattg aaaattctgg
     1921 tatccctgct gcatatggag ttatatcata taaatcaaaa tatacaacta gattctcatc
     1981 ttgcaagtaa aagttttgat tctcttttat acctttaaaa ttatatattc ctatattttc
     2041 ttcatccttt ttttcaagtt cagctatttg tcttttaatt tcttcatcta taacttcttt
     2101 atatttagta ttatccttaa acaagtccat taattctaaa aattttccag ttctcatatc
     2161 cacattatat gctatatctt gataaaatcc atgtgctcca ccactataag tataatatct
     2221 cacttttata ctaagagcag aatcagtatt ctttttaagt tcaaagtcta catttgcaac
     2281 aaacttattt ttctcatcag gattatcctt aagatactgc tttgcttctt tatatgattt
     2341 attataaaat tcaaatatgt cattttttat cttatcattt gtagaccttt caacaatttt
     2401 atttgaattt gttattacag gcatgtttat agtactttct aaatactcat catttttcac
     2461 tattgtttta cttcctattg tacttactga taaagtttgt ttactatttg tattaccctt
     2521 tggtaatgac tggttactca taacagtcac tgcttcctta ttactattta aattaattga
     2581 agcatctttc cttaaattat tatatttata gtcatgttta attgccaaaa cagccattat
     2641 agtcaatgtt aaaacaaata catatcttaa aactttagct tttgtatcga ctttaaaaaa
     2701 tttcatatta tcattttcct cctaaatata aatctctctt attatatttg gagtttctag
     2761 ggttttttat ccatataatt taataaaaga ttaattttta tttataaaaa attaatcttt
     2821 ttgttttaaa atattaatat gtcttatcaa acagtttgaa atttcaccaa gaggtaattg
     2881 taacataaca gaacctctat caaaagctac cattggcatt ccatatacta tacaagaatt
     2941 ttcatcctgt ccaattgtaa atgaaccatt ttctttcatt tttaaaagtc cacttgctcc
     3001 atcataaccc atacctgtaa gtattattcc tattgaattt ttacctgcta cttctgctac
     3061 tgaatcaaac aaaacgtcta ctgatggaca gtgaccactt attctttctc ccttttcaca
     3121 agttacataa tatccttgtt tatccgtaca caatttcatc tggtaacccc caggtgcaat
     3181 taacacattt ccttgttcga ctctatcatt attcttagct tctcttacat tcataataca
     3241 ctgcttgtca agccgttgtg catacatata agtaaatata gctggcatat gttgaactac
     3301 aacaatccct ggtgttgatt ttggtaggtc ttttataatt tcaagtattg cctctgtacc
     3361 acctacagat gcgcctatag caataaccat attattaaaa cgttccacat taccgcctcc
     3421 aaaaaatcat atatcaaaaa taccttttta tcgtttatat atagcaggtt ttacatattt
     3481 gtatttagta ctacttctgt tgattacttc tgcatgtcct acaaacaaaa aactatcttt
     3541 tttggtagca ttataaaatt tatttataag ttcttctctt gtttttaaat caaaataaat
     3601 cataacattt ctacaaaaaa tcaaatcaaa atgttgatat gagaaatcat tcattaaatt
     3661 aaacggctta aaaattacac tttttctaat cttatcacaa attttaaatg taccatcctt
     3721 gttgtctata aaatacttct tcttccataa ctcaggaaca ttgttaacat ttgattctat
     3781 gtatatacct cttttagctt tttcaagtga gttagttgaa atatctgtgg ctatgatttt
     3841 aatgttccac aactctttat tatatccaaa ataatcatcc aaagtcatag ctattgaata
     3901 cgcttcttct ccactagaac atcctgcact ccatatattt atgtttctta ttttattatt
     3961 ttcttcccaa aaaggaagta tactattctg tataaactca aaatgttgag gttctctcat
     4021 aaaaaatgtg tggttagtac tcaatctatt tattaggttt atagcttcat ttcctgtctt
     4081 atctttaaat aatagattca tatattgact aaaagaacta agttttttct ctatcattgt
     4141 attgtataag cgaccttcaa ttaacgctct ttttttactt aaatcaatac catattcttt
     4201 ttttacatgg tttacaagaa ctataaattc ttcatctgtg agttttatca tgcaaaaact
     4261 tcctcctgct aatttatcag aactaactat atgctattaa tcaaaaactt tcgaatatct
     4321 aaaattaata tagaattatc ttcaactttc gcaatctctt ttatatcttt attaatatta
     4381 gtgttgttag aattagtcgt ctctagtaaa tttagatttt ctatatgaat aacatcaaca
     4441 actttatcta caataattcc aacttgatac tcatcaacct ttgtaattat tatacaagtt
     4501 ctctcattat aatcagcttt aggaagattg tactttatat gcatattaat aactggtatt
     4561 attcttcctc tcaaattaat aactccactt atatatgttg gaagacatgg tacatacgtt
     4621 attgattgaa atcttatggt ttcaatcaca ttttctaatt ctattccata aataacatca
     4681 ttgacataaa atgttaacac ttgtttaata atttcatctt tagccatact ttaaatcccc
     4741 taatatattt ctataatgct atctgcatct ataattaaac ttatacttcc atccccaagt
     4801 attgtacatc ccgataaacc cttatttttt atattaaatc ggttaaaata aactggaaat
     4861 ggtttcacaa caacttgctg attacctatt atttcatcaa caaaaatgca tactgcttta
     4921 tgctcatttt caataattat catattccca ttcatcagat tggttacttt tgtttgaata
     4981 ttatatattt tatgtaacct tataatggga atacaggctc catatattgt aattaactct
     5041 gtcttatttc cttctgtaat tatttgattt aagtctgtaa gtttaaatgt tcttcttata
     5101 gatgatattg gtaaagtaaa tagtgaatct ccaactttaa acttcatacc ctctactata
     5161 gaaagagtta atggtatttt tatagtaaag gttgtccctt catcctgttt actttttact
     5221 tcaattgaac ctccaacttt ttcaatactt ttacgaacaa tgtccatgcc tactcctctt
     5281 ccagaaaatt cagttataga ttcttttgta gaaaagcctg gagtcataat caaagaattg
     5341 acctcgtcat cagtatactc attactttga tgtttaagaa gaccttgttc cttagctttt
     5401 gccaaaatct tatctctcat aatgcctcta ccatcatctg aaatacttat cacagcttct
     5461 ccgcctagat tttcagcaga taaaactatc tttcccactt cttctttacc tttcgctata
     5521 cgctcctcaa taggctctat tgcatggtcc atagcatttc ttataaggtg cataaaaggt
     5581 tctgctaaat tatcaattac actcttatct acctctgtct ctgctcctat agttattaac
     5641 tctacatttt tatctaattt tttattcata tctcgtacaa ttctatgcat tttttgaaat
     5701 acaccagcaa tttgaatcat acgcatagac attactatat cttgcaattc atctgtaagc
     5761 ttgtgtaatt gtcttgttgc cttattgaaa ttatctatat caacacctgt agaatttacg
     5821 ctatttacaa ccattgattc cataattaca atttctccaa ctatattttg aagtaagtcc
     5881 aatttttcta aatttacact cataatactc tgcttactta ttggtaaatg ttcattttct
     5941 tcacttagac tatctttttc catatcagtt ttttcattta aaacatcttc ttgtatctca
     6001 tcttctgtat agttattttg ataactttta cttactttat tattatcttt taatttattt
     6061 tctactgcat cattgtttga tgtacttttc atttctattt cttttttact aatatttatg
     6121 tattctttta catagagatt atcttctata gttttataaa ctattgcctt atcctcttta
     6181 gctacaaatt gtatataaaa cccataactt ttaatatact ctgtagactc tgcatttgtt
     6241 tctacatctt ttggataaaa atctataaat tcacagtaat ctctaagttc aaatacaagc
     6301 atgaaagctc tcacattttc catcatgcaa ccttgttcaa agattatttt tactacatca
     6361 gagtcttctt tgtattcaaa atttgaatcg attacttctt tttcgtcttt actttctaaa
     6421 tttgcattat cctttgattt catagaactt gataattcca aagtactcac atactcttca
     6481 attccttcaa taaaattaga gtaatcagaa gacatacaac ctcttgattg taactcatct
     6541 atatctcttc ttataaaatc taatgattga aagactaaat caaataatag gtcattgtct
     6601 aaaacttcta ttttaccttc acgtatagca taaaacaagt cttctacact atgtgctaaa
     6661 gcagatatat tgtctaaccc catcatagat gctgaacctt ttatcgtatg cattattcta
     6721 aaagtttcat taatgttgtt atgagtaaat actttctctt tttctatttg aatcataatt
     6781 tcatctaatt gttcgagtaa taaacttgtc tcaaatataa acatatctaa catttttctc
     6841 atactcggtt caatataatt cacatttatc acctacgacc tacaaataat tttctattat
     6901 atatgcatct cataatttaa atccttgatg attctcttat ctcactatat gtacctcata
     6961 atttaaatac acaattattc tcttacttca atatatatac atctcataat ttaaatacat
     7021 gataattctc ttatttcaat atatatacat ctcataattt aaatacatga taattctctt
     7081 acttcaatat tcatctcata atttaaaccc atgatgattc tcttacttca ctttccttta
     7141 gatgaaattt ttctactaat tcttttaaaa tttgagcttg agcagacatc tcttctgagg
     7201 ctgctgcact ttcctctgct gttgctgagt tcatttggac tactatggaa atttgctcta
     7261 ttccagataa aatctgtgta attgctactt cttgactatg tacagccgaa gaaataccat
     7321 taatataatt agtagttttt tctacaccat ttactaccaa gtccaatgca tttgcagtct
     7381 ctttagcaat tctgacacca ttttctactg ttttaatagc ttcttctatg agaatagctg
     7441 tattttgagc tgcttttgca cttttaccag ccaaagacct aacttcatct gctacaactg
     7501 caaatcctct accatattga cctgctcttg ctgcttcaac agctgcattt aatgcaagaa
     7561 tattagtttg gaatgctatc tcatctattg ttttgattat ttttgatatt tcactcgatt
     7621 tttcacttat ttcacccatt gatgtcatca tatcatccat acatctactt ccaaaaccaa
     7681 cttgtgatgc agattggtca gatacctcac atgcaagact agcactatct gcacacttct
     7741 taattccatc tgatatctca ttaatcgtgg aagctaattc ttctactgaa ctagcttgtt
     7801 cagtagcacc ctgtgaaaga gcttgtgcac ctgctgcaac ttgttctgaa gcacttgcaa
     7861 cttgttctgc tgataaattt atttcagaaa aatcaccatt aaaagagttt attatacttt
     7921 ctaaagatat tttaattgat ttaaaatcac ctataaattc ttggtctatc tctactctta
     7981 aatctccttt tgcaatacta gttaatgtac tgtctataag gtctatgtaa tttaaaagca
     8041 tactttgcat ctttttgaca gaactcacta atagtcctat ttcagattta ctttcttcaa
     8101 cgtctatact tgttcttaag tccccagatg caattcttga aaagtgtttt tctactttat
     8161 taataggaat cactattttt aattttatta ctgtatattc tattattgtc aatattatta
     8221 aaagggaaag tataaatatt gttcttaata ttagactttg taattctttt tttacttcta
     8281 caattttgga atttgaacgg gtaactatat cctcttgaaa ttcatttatt aaagaatcca
     8341 ttttctcttg ggagtttata tagtcactac caaaaattat actttgagct ttactcttat
     8401 cattactttc gactgccttt attgcacttt gttctgttgg tactaaagaa tctgatattt
     8461 cttttgcttc taagatttta tttgactcgc tctttgtaag accaattttt tctaatttgt
     8521 ttaaagctga ttctcttgtt tttccgtata attctttttc ataaatatct ttattctttt
     8581 tttctcctgt aaatacatat cttcttaata catcacttat ctctctagtt gtatctttta
     8641 tatactgact ttgagtcctc aaattattca tatcattaat acttttttct actttttcaa
     8701 atgctttata agatgaaata gaagaaaaaa tccctgctag aacagccaat actataataa
     8761 tcaacaatac aattgctaat ttagaaagct ttacttctct tttcatatct gtactccttt
     8821 ataaagtaag tttatatctt ttttaatcct ttcattgtac tcactacgct acaatctttt
     8881 cctaagtttt taccctcata cattgcttta tctgctaagg atatgttttc ttctaatgat
     8941 atatttgagt ttacttctac tactcctaat gtaatagtgc actttatttt atgttcttta
     9001 tagttgaaat caaactcctt tatctcttta cggattcttt ctgaaagtat cttagcacct
     9061 tctattggag tatttgtgag cattatcaaa aactcttctc caccccatct tgatacagta
     9121 tcaatttgtc tacaattctt ttttattata cttgatatta ctgttaacac gaaatcccct
     9181 gcttcatgcc cataagtatc attgataacc ttaaagtcat caatatcacc aaggataagg
     9241 gatattgatg tttcactata tttattaatt cttctttgct ccataagctg attaattata
     9301 tgtcgcctat tgtaaagacc tgtaagataa tctcttacaa cgagtctatt caatttttca
     9361 agagaagatt ccagttcatt atttatcttt tttaatttat cttgagattt ctttacttca
     9421 agatgagcta taacacgagc ttttaattct gtcatactaa aaggtttcac catatagtca
     9481 attgctccta caccaaatcc ttttactatg tctgtatctg tattttttga agttataaaa
     9541 attataggta tatctgctgt acgagcatta gattttactt ccttacaaaa ctcaaaacca
     9601 gagttatctg gtaaaattat atcaagcaaa ataatgtctg gtataaattc ttcaataaat
     9661 tcttttgcct ctattgcatt aaatgctttt ttaaccttaa aattatcttt tgtaagtgtt
     9721 ttatctatta agtcacacat cagaacacta tcatcaacga ctaaaattgt tccctgttgc
     9781 ttatttttca tatacaaacc tctcttaaac ataatatatt caaattttaa tgatttaaaa
     9841 tttttatact taataattat accactatat tcttaaatgt tctcatcaca atctttttat
     9901 aataacactc caactacatc cctatattac atgatagtgc aatcaaaccc attgattaat
     9961 tcatctatta aaacttcatc tttatctgtc aaaagtttct ctaaatctag taaagtaatt
    10021 attttacctt ctaattctcc aactccactt acaaaataat ccgaatattc tatagtaact
    10081 cttggtggag gtgatatttt gcttttttct aagcttacta tatcatcaac tctatcaacc
    10141 acaaatccaa ctaccaagtc ctttatttca gttactacta tatacatgca atttgtagtc
    10201 attaattcat cttttttaag tctcaaacgc atatctatta tcggaatgat ttttcctctt
    10261 agatttatta tgcctttaga atatgtaggt agttctggaa taaatataat ttcttgattt
    10321 ccagtaattt ctattacctt ttcaagttca accccaaaat cttgctcatc tactttaaac
    10381 tttagatact taattccttc atcaattagt ccataatcta aatatgggtc atctggaaat
    10441 ctcatttaat acctccctcc taaaatacac tttctatgaa atatatatta taatttcttc
    10501 ttacctttat ttattgaatc tacaagtaat tcacccgtct cagtgtaaaa acgtattgtt
    10561 ctaccataat tcatacctgt gtcctcagct aatattggaa tatttaatcc taaaagagtt
    10621 ttttttactg cctcaacatt cctatgtcct atacttgcaa ttactgaatt gctacttcct
    10681 aaaaacatct gagcacctcc agcaattttt gcttttatat atattctatt tgcacctata
    10741 ttctccatag atttaatgag ctcatttatt cctgtgtcag caaatttaca cttattttca
    10801 atgttaatag catctttact atatggcaac ataacgtgta acattccacc aattccagct
    10861 actttatcta tcaaacatac tcctacacaa gaaccaagtg cataagtaac taaaacattt
    10921 ggtctatagg ctatcttcat atctgcaatg ttcactacta tctctctatt catacttcta
    10981 atcccaacct cacgagtatt tctctaagtg agctcatttc tggaatcatc aaaatgtgac
    11041 tagtaaaata attatcactc attttaaatt tattttctat aaataagact ttgtcaccaa
    11101 catctgaaaa tcttatcata agtacattta gaacagctcc aaccatatca atacatatat
    11161 ctggaattga aacacttata gtcatgttta acatagatgc aatagcattt acatatgaac
    11221 ttgccataat atttcctatt tccttaattg ctgaaatttc aattgcctca atctcatcta
    11281 aaaaagcttc ttctttatta aaaagagaac ttagcataag ttgagttatt gattcatcca
    11341 acaaaaacat aaacattcca ttgatatcac ctttcatatc gagtaaaata catactactt
    11401 tgttttctgg accaccaagc aaatttgtcg cttcattata ttcaagtatc ttgaccatag
    11461 gtattaatac ttctacattg ctatttatca tggatgcaag tgcagtaatt gtattcccag
    11521 agcctatatt accaatttct ctaagagcat ctatatgaac atcatcaagt tctaaataat
    11581 ttataatata aacccctccc tttattattg catttatttg cttttcattg tattagtgta
    11641 tatttacact tttattttaa agcattatct acaactttaa ctaatgtttc tgttttgaag
    11701 ggcttcacta taaaatctaa cgctccaagt tttatggctt ctacaatcat attctcttgt
    11761 cctattgcag agcacattac aaccttagca cttgaatcca acttttttat ttctcttagc
    11821 acctctaaac catctttttt tggcattgta atatcaagca acatcaaatc aggcttttca
    11881 tatttaaata tattacacgc ttcttctcca tcatttgctt ctattaaatt attatagcca
    11941 cttttactca gagcttcttt aattatcatt ctcataaaaa tagcatcatc tactatcaaa
    12001 attttatttt ccataaaact aactcctcca tatgtacaac aataaacgct tttatcttca
    12061 gttattgtct atactatctg actatttttc gctacacaat aaatacattt cattgataaa
    12121 taaaagtaat tatttatgcc atattatact taattctctt aacataattt gtcaacaaaa
    12181 aaacttatat atctattgta atatatgttt ggcgttttga cgagttatta aaaatataat
    12241 tgtataaaac ataaaaagtt atcaaaagta attaaattat aataaaacaa ctttatacct
    12301 tttttatgtt tgtataaaaa aatttttcag attcattaaa atcatttctg tagattcata
    12361 taggatttga ctttctcaat atctaataga tagttgttta tttacttaat tatatttctc
    12421 tatatgtatt atcgattaaa ttagatttag ctttatacat tattttttat atttttcaaa
    12481 ttgtatactc ataaatccag aagtattcta atgtgtttat aatacttttt ttcatatttt
    12541 aaattaaata acaaatcatt atatttacaa gtatcattta tcaataaaca atattaaatg
    12601 aagaatatgt ctgaagattc aaagtgatac tgataatatt aattactaaa aaagcagtaa
    12661 atcttttaca gatttactgc ttatagttat aaataataaa actatctata ataaatgtac
    12721 tatactcaat acttcattca atatagtaat aacaaatcta ctttattcct atgtaaatat
    12781 gaacttcttg tttctttgta tcaaaagtat tacattgata ctcttcaaaa tcacttatat
    12841 aagtcctatc aaaatccatt tgccaaaact taaaccaaaa atctcctact tctttttgac
    12901 ctcctactat aacaaacttt gcatacttac ctgctggtat aactttacta ataatacttt
    12961 ctccaacagt attattagtg tttaattctt ctaaattctt ctctttatca gaattactat
    13021 ttacttcaca acatgcaaca aagctatacg gacttgtaaa atcaccctgg taatctgtat
    13081 atagacctat tgtcttgtca ttctttttac cctttatagc attatatatc cctttgccca
    13141 taaatttttt ccacaattca cctatatcat ttaccgcttg tccatcttta tttgtagtct
    13201 ccttcgatat tcctataact attttctcat ttatctctac tatttcataa ttcatacttt
    13261 atacctcact ttgtttttat taatatattt tatttttaac taattcaatt ataatttata
    13321 atatacgaca cctttatgtc atatttttaa tataattaaa ctcagtgaga tattatatac
    13381 taaatgcaag atattatata tttaataaaa tctttaatct agcattatat tataatgaat
    13441 aaattttaga caactccctt agtctagtta ttacattatc cctaacatct ttaggttcaa
    13501 gtacttcaac attgtcacca aacgataaaa tatatccata aatccattca ccaataggaa
    13561 attctgtaat tacatcatat gtatcatctt catttttagt tattaaatcc ttattaaaat
    13621 catcaaatac tctaaaaagc atcttttctt taaacctcaa tttcaacgtt atagtatttt
    13681 ccttaattac tttagaatca ttcaaacata cttcttctat tatctttctt gaaaatactt
    13741 catcctttat agataaattc cttatcctac taattctaaa tatcctaaaa tcatctttta
    13801 gtttacaaaa tccatacaag taccaagtct tactcttata cataagcttc agtggttcga
    13861 cagttctgtt tgtctggctt gacaaactat ttacataatt aaaatttata gtattacgcc
    13921 ttaaaatagc ttcttttatt tttgtaaatt tatcatcttc attaaaatta cttccccatt
    13981 cagtaaagtc tatttcaatc cagtttgaaa aattctgctc tccaaatatt gagccaattt
    14041 tatttactac tgaatttatt tctggatact tagtcgcctg taatgttttc agtgccacta
    14101 ttaaactctc tttatctttt tttgacaata tagccttgtc tatagaatat tcttctatta
    14161 aagatatccc tcctcctttg cctttcgtca tatatactgg tactcccgac atagacagag
    14221 tttctatatc tctatatatg gttcttgtag aaacttcaaa cctatctgcc aactctttag
    14281 ctgttactaa ttttttattt aatagaatta ctattatttc tgttaatcta tttattttca
    14341 ttcattacca cctactaaaa ttattaaatt tatttaatct aaattattct tactaatttt
    14401 taaataaata aaatcttaga atcttatcta aattattctt acatgatttt atttactttc
    14461 tattatcttt ctcactttgg atattatcat cttaatttat ttattactat atcaatttac
    14521 ttattatcat ctcatttgtt atcgtcttac ttaatttact tatttctata tcaattcact
    14581 tattattacc tcacttgtta tcatcttact taatttactt atttctatat caatttactt
    14641 attatcatct catttgttat cgtcttactt aatttactta ttgctatgtc aattcattta
    14701 ttattatctc acttgttatc gtcttactta atttacttat ttctatatca attcacttat
    14761 tatcatctta attcatttgc ttattatcat ttactttatt caatttctat atcaaaatta
    14821 gtatttgtac ttaatactta aaattaattt aaagtcttta catattattt attttctatt
    14881 gtaatattca tttccatact ttactaagct acttccactc atttatttta aaatttcaat
    14941 ttactatttc tcaactctat attattattt ttcaatttta tattactaat tttaaagctt
    15001 tttagctatt attcctacaa tatttaaaca attttttcat aataaagcta tattacaata
    15061 tattcaaaat atgtaatatt ttagatattt ttcgttgaca atgttaaatt tttgttttat
    15121 ccttaattaa ggacatgtta ttgacatttc tgaaacttat ttgaaatagt tttttcattt
    15181 tatttaggaa aacgtattat acttaagaaa acgtattttc tcatttcaga taagtaaaat
    15241 atttattctt ttggggagga aatcatggaa attaataaaa aacattttat tcaagtattt
    15301 ttaacttgct taatcttggt agtaatatgt gaatttatag ggcaaagaac tatagctatt
    15361 ggaaaagcct ctatagtact gttccctatg ctttatgcag ttataattgg acttataata
    15421 acaccagatt tattaggtaa aaaaattaaa gcacttaaaa aagtggttgg agaaaaagaa
    15481 ataaatattg ctggtgaagt tgttggaatt gcactagtaa tgcttggtat aaaatatggt
    15541 actacagttg gaccaaacat tgacaaaata attcaggctg gaccagcatt tatcgctcaa
    15601 gaatttggtc atatacttgc accaatcgtt gcattacctc ttgcattaat gtttggaatg
    15661 aaaagagaag ctgttggagc tactgcaagt ataagtcgtg aaccttcttt aggagttata
    15721 tcagaaaaat atgggataaa ctcaccagaa ggtagtggtg tacttggtac atatttaatg
    15781 ggaacagttc ttggtactat atactttagt gtactaggtt caatatctat ttatagtggt
    15841 cttcacccat atgctttggg aatggcctgt ggtgttggta gtggaagtat gatgacagca
    15901 gctgctggtt cattatctac catggtacca cctgaaatgg cagatacaat acttgcctat
    15961 gctgcaacaa gcaatatgat gtctagtata acaggaatta tattcttagt ttttgtatcc
    16021 ttaccattta ctaattttat gtataagatt ttagaaccaa aattttcgag aaataaaaaa
    16081 actaaagaaa ttaaatctac agaaggagag tgctaataaa tgtttgctaa tttaaattta
    16141 aagaaaagtt catatcaatt attggttatg tctgttattg gagttataat tcttatagga
    16201 caaagaatta gcgttggtac atctatagtt acagctcttc ctggtatggt gatgctaata
    16261 ttagctgcta tggctgctat gattataaaa gatttatttc ctaaatcaat ctttccagct
    16321 tttggatttg caactataat cggcctttta cttagtatgc catatagtcc aacatctgaa
    16381 gtattcttaa ctaacactaa taatattaac tttatggcta taactactcc actactagct
    16441 tttgcaggaa tttctgttgg aaacaaaata gaagctttaa aagaaatgtc atggaaaata
    16501 gttataattt cacttattgt atttacaact atattctttg catgtgcgag tatagctcat
    16561 atagttttaa gtattcaagg taaaatatag gaggaattta ttatgaataa agaacaatta
    16621 aaatctctag taataaaaac tatagatgaa aatagagaaa aaatattaaa aataggtcaa
    16681 ggaatataca aaaatccaga atatggatat aaagaattta aaactacaga agctgtttca
    16741 aacttttttg agcaagaatt aaatttatct gtagaaaaaa atatagcagt tacaggatgc
    16801 aaagcagatg caaattctag caagaaaggt cctcatatat ctatacttgg agaattggat
    16861 ggtatatcat gtaaagaaca taaagatgct aatgaaatag gtgcttctca tacttgtgga
    16921 cataatattc aaatagctgg aatgttaggt gctgctgttg gtttagtaaa aagtggcgtt
    16981 ttagaacatt tagatggtaa agtatctttt atggctactc ctgctgaaga gtttattgag
    17041 ttggaataca gagagcaatt aaaaaaagaa ggaaaaataa cttattttgg tggaaaacaa
    17101 gaattaataa aaagaggtta ttttgatgat atagacatat ctatgatgtt tcatgcttct
    17161 gatttaggag aagataaggc tctagttggt cctgagagta atggatttgt tggaaaaaag
    17221 gttaaattta taggtaaaga atctcatgct ggttctgctc cacatgatgg aataaatgct
    17281 ttaaatgcag caatgcttgc tataaacaac gtgaatgcac ttagagaaac ttttaaagag
    17341 tctgaaagag ttagattcca ccctatcatc acaaaaggtg gagatatagt aaatgttgtt
    17401 cctgctgatg ttcatatgga atcatatgtt agagctagaa ctataaatgg tatgattgat
    17461 gctaatgaaa gaataaataa ggctttgatg gctggtggaa tggcagttgg agctgatgtt
    17521 gagataactg aaattcctgg atatcttcca atattacgat acaaaagtct tgataattta
    17581 tttaaaaaca atcttgaaga tttaggtcta aaaggaaaag ttattgatgg tggagatttt
    17641 acaggctctt ttgattttgg agatgtgtct catataatgc ctactcttca ccctatgatt
    17701 ggtggtgtaa aaggagctct tcatacaaga gattttgaaa tagttgatga agatttagct
    17761 tacataattc ctgctaaagc aatggcactt acagttgtag accttctttt tgataatgct
    17821 aaggatgcta aagatatatt agataccttt actccagtta tgactaaaaa agaatatcta
    17881 acattcttag aaaaacacga taaaacttta taagtctatt tttataatag ggtggtatct
    17941 actgtaaaag ttataccact ctttgttttt gtaacagtat acttcttttc ttttagtttt
    18001 tagattaaac taaaatatat tatcctcctt aaaactttta gagctacgtt gaaatatcag
    18061 tagaactatg ctatattctt tctaattaat ataaatttct attctaattc aaggtggtga
    18121 aaaaatgttt aatgcaggaa atcgaattat aaatacatgg ttgtacccta ttcaagatgg
    18181 ctttgtcttg attgatactg gatatgaaaa tggttttaaa catttcaaaa aacgaatttc
    18241 taaattcaac ataaaaatca aagatattcg atacatattt ctaactcatg ctcatgatga
    18301 ccatgttggt tttctaaatc agattctaga cgaatctcct aatacaaaga ttgttatgca
    18361 tgataaagct ttagaaattc tatataaagg tcaaaactct tttattggtg gttgtaccag
    18421 ccgtactgcc tttctctttt gccaaattat gaaactattt ggaaaaggtg agcatagttt
    18481 ttctccactt aaacaagaat ttgaaaaaag gtgtattctt gtgtctgaca agaatcgtaa
    18541 agaaattaaa aaagaactaa atggaaaaat tatagataca ccaggacata ctgctgattc
    18601 gatttcacta ctaattgatg atggtgtttt attttgtgga gattctgcaa tgaatggatt
    18661 tccaagtact cacaaaatta ccatatttac agaaagcaaa ctagaattta ttcaatcttg
    18721 gaaaacaatt atcaatacaa aacctaaaat gatttatcct ggacatggaa aaccatttga
    18781 atacagtaaa ttagaacaaa atctaatcta tgtaaataaa ataaatttat atcctctaca
    18841 taattcaaaa gatattcaca gatttttgta gaaaatacaa agtaaatttc tttgattaat
    18901 taaaaaatct aacactttac tacgctactt attttaataa cttaatcttc cactagcttt
    18961 tcataaaatt ttgttttaaa attaatttta aagtgcatat gttatttaaa tacattagat
    19021 aaaattcgtc attaatctac ttaaagcata tttaactaac actactcaac cagaaaattc
    19081 agaaaactgc attgacacag gaaaaagttt attttatact ttttttagga catattgtgg
    19141 acacgtctta aatcgacaaa cagaatttaa attgtaagat taaccacaat acttattttt
    19201 taattatatt tttaaacatt agggaggata ttatgaatga taacgtagtt aagaagaaaa
    19261 acttttttga caggacatta aacagaatag aaactgttgg taataaacta ccagacccag
    19321 ttacaatatt tttagggtta tgtgtacttt tacttatact atctagtcta gttggttcta
    19381 tggggatatc agtagttcat cctggtactg gagaaactat aaccgctgta aatttattga
    19441 ctgtagaaca gcttcaaatt cttttaggaa acatagtcag caatttccaa gggttcgctc
    19501 ctttgggtct agttctagta actatgatag gtgctggtgt atgtgacaaa acaggactta
    19561 tgacagcaac aatcaaagca tcagtaagca agattcctga aacaagagta actcttgttg
    19621 taatgactat aggtatgctt gccaatatag cttcagatgc aggtacaata ttatttccac
    19681 cattagctgc acttgtatat cttggtgttg gtagacatcc acttataggt ttattttctg
    19741 gatatgcagc agtctgtcta ggatttgccg caaacattat gataagtgtc aatgatatac
    19801 ttgctgcaag ttttacagtt ccagcagctc aaatgattga ttctggattt caagccaatg
    19861 caacaatgaa cttatttttt atgatagcat caacttttgt tctaatactt ttggcaacat
    19921 gggtaacaga aaaaattgta gctcctagat ttggtaaata tgaaggaaat gcagaactag
    19981 atgttgatgg aagtcttagt gatgtagaaa agaaagggct taaaaaagct ggtataagta
    20041 tattaatata tgtggctatt atagtagctc ttagtgtaat tggtaaaaaa ccattcttag
    20101 ctgacccaga aacaggagat ttactatcaa acaatgctcc tcttatgaaa ggtatggtac
    20161 ctataatagc actagcattt ttcatacctg gtgttgtata cggaaaaact ataggtaaaa
    20221 taaagaagga taaggatgta gtctctataa tggctagtgc aatgagtgat atgggtggat
    20281 atataatact agcatttgct gcttcacaat ttttgcaatt attcacaaat agtaatttag
    20341 gtctgatatt agctgtaaag ggcggagaat ttttaaaatc agcaggaata aatggacctt
    20401 tattgttgat aggatttatt atattatcat gttttataaa tttatttata ggtagtgcat
    20461 ctgcaaagtg ggctattctt gcacctatat ttgtaccaat gtttatgatg gttggataca
    20521 atccagcact tactcagatg gcttatcgta taggtgattg tataacaaat ccacttagcc
    20581 cattatttcc gtacttccct attatactag cattcacaag aaaatacgat aaagatgctg
    20641 gtatgggtac tgtaattgct aatatgatac catactctat atcattctta atagtgtgga
    20701 ctatactatt aatattgttt atggtattta atattccact aggacctgga atacttcctt
    20761 catatagcat gtaatttatt taaatctttc taaaaggaga aataatttat gttagataaa
    20821 aatagactta taaataattt tatggatatg gttagaattg atagcccatc taatcaagaa
    20881 ttagaaatgt ctaagtggtt ggtaaactac ttaaaagaaa gaaatataga tgccattata
    20941 gatgatgcag gtgaaaaata tggtggtaat acaggtaatg tcattgccta tataaaaggt
    21001 gaagaaggaa gtagaccact ttgtttatgt gcacacatgg accaagttca accttgttta
    21061 ggtgtaaaac caatactaga tggtaatgta gttagaagtg atggaactac tacacttggt
    21121 gcagatgata aagctggaat agctgctata cttgaagctt tagaacatgt tattacagaa
    21181 aaaataccac atagagatat ttatctttgt tttacaatct gtgaggaagc tggtatgcat
    21241 ggtgtcaaaa actttaatcc tgacaacttg ccttgtaaag atatggtgat tttagattct
    21301 ggtggagcta ttggttcgat agcatacaaa gctcctgctc aacaatctat aaaaatctct
    21361 tttcatggaa agaaagcaca tgctggtata gaacctgaaa aagggttaaa tgctatatta
    21421 gtagcctctc atgcaataag caacatgcac ataggcagaa tagattcatt gactacttca
    21481 aatataggta aaatagaagg tggtggagct acaaacatag taactgataa ggttacattg
    21541 actgctgaaa ttaggtctca tatacctgaa actttagagt atgagcttaa tcatatggaa
    21601 aaatgttgta aggatgctgc atctaaattt aatactactt atacttttga acataatatg
    21661 tcttacccta gttttgaact tagtagagat agtcacgttt tcaagttaag tgaagaagca
    21721 ataagacaag ttggtgttgt tccaaatcca atggtaattg gtggtggaag tgacgcaaat
    21781 atattagcta atcttggata taattgtgct atattaagtc taggtatgta tgatgtacac
    21841 acagttaatg aatatgtaaa tatagacgaa ttatatgata ctgccaaaat agtttatcat
    21901 atgattaaat tataaatatc ataatataac tctttaaatt ataaaaataa aaacctatgt
    21961 atcttcaact ttataagtta tatattaaag ttgttttaca taggttttag tattttatat
    22021 aataatttgt tctagcattt ttaataacaa gctctagtat tttacataat catttgttct
    22081 agcattttta ataacaagct ctagtatttt atattaataa tttattctag tatttttaat
    22141 aacaagctct agtattttat ataataattt gttctaattt ttttcataat aagctttaat
    22201 actttatata gtaatttgtt gtagaatttt atataatata attatttata cagttttata
    22261 aaatatctta aaacagtatt tcagtaatat tttttggtct tcctccacca atactagtct
    22321 cttttgcaca tattcgacct aaacctgcat ttactatttt atttaatata cgtcttgcac
    22381 ttctttcact tacatttaga tactctgcta actcttttga atcataaatc ttactttttc
    22441 tattctcatt tatagcaata atttttgcaa ctgactcaca actcattcca gtctttttag
    22501 atatttcgat taccttttca tcagatagca tcaaagaata atttaattca ttttcggaag
    22561 ctaaaggtcc tcttatgttt tcatcttcat ctaccaaata tataccaatt tcttttgaat
    22621 ctatggagtg tcttaatgct ttatgtgcat tattttcagc ctgatacgca gttactccag
    22681 taccaattcc tatactaaga gaaaagccca tgtcttttat ctctctcttt agattgaata
    22741 gcttatcata attatactca ttatcagcta cccctttatg aacaaataca acataatcat
    22801 ttcttccaag taaaaataag gaaccttgaa tacttcttac atagtttact acaagcttat
    22861 ccatatctga tttttttatc atgtcagaat aatagttatc tatcttctct ttataatcta
    22921 ttaaactcaa tatttcaaca gcaatttgag aaaatcttgc cttacttaga gcatattcac
    22981 tctttacctt gtcataactt tctttgatta attgtatagt agcttgtaaa cgaaatacag
    23041 gatagcctct ttcttttaat tcattatata ctgcaccaaa accagttaac attatatccg
    23101 tcttattttc ttcaaataat tttatatgcc attctacaag ttcagactct cctacttcca
    23161 aagaaaatgg attacaaaat acactcgttg ctttaatatc aaattcttta agtgcatctt
    23221 ccacaacata tctatcaact acatctatac tgaatttatc taattttata tttgcacttt
    23281 ttattgccca aaatgccttc attatactcg tcccacttct cggtacaaat gaatgtggct
    23341 tacttatctc atacttagat tttataaatt cataaactgc acatcctgta aatataatag
    23401 catcacattc gtcttcacat ttagaaataa cttctattgt atctactact ttttctctta
    23461 catatatttt agtctttaaa tcactgtcta tctgttttaa atcatccttt atcttaaacc
    23521 cagagtctga aggacctata atacccacta tcataaactt cgctcctaat ccataaatat
    23581 tatacttttt aaaaattata tcctcactat tttctacttc tatttaatta ttttgaacta
    23641 ctccatccta cctacattta gaatggaata attagcttat ttttgataaa gtaacttctc
    23701 aaaatcagca cttggaatag gcttacaata ataataacct tgaattacca cacaatctaa
    23761 actcactaaa aattcagctt gttcttttgt ctctacacct tctgccacta catccatatc
    23821 taaatctttt gccatggcta tagtgtgctt taaaactatt ttttctctgt ctgtgattcc
    23881 ttcctcatta aagaaaccac aatctatctt taatgtatca atattaatat tttttaacat
    23941 atttaatgaa gaatatgctg aaccaaagtc atccatattt aaaacaatac catccattct
    24001 aaggtcggct attatcttag taaataattt tatattttta ataaataaac tttctgtaag
    24061 ctctaattct aaaaaagatt ttggtatact atatttattt attaaactta aaacaatttc
    24121 tttaaaatgt ggattatgca aatgtaatct tgatacattt acagagatag gaactggctc
    24181 ttcacctaaa tctatccatt ttctaatcaa agaacatact tgttcccata catacatatc
    24241 taatctgata ataaacccat tcttctcaaa tagtgaaata aatttaattg gaggtattat
    24301 acctttttct ggatgaaccc atctaaccaa tgcttctgca ccaacaattt tatttgcatt
    24361 aagattatac ttaggttgta aatatacatg gaattgccca ttttcaagtg cgtattccat
    24421 ttccctttcc atctgttttt cttcaagtgc atcatttctt atagtatcat cataaaatat
    24481 atagttgttg atactttgtt tctttacttt tttgtgagca tatcctgcca tttcacacgc
    24541 atttgtaatt ggaatatgat tatccaaaat tctataaacc ccaaaacatg gtactaacat
    24601 atattcaaat ttttttctat ttaagctatt tttaatctta taaattactt tatgaatatc
    24661 tctatcagag taactctcat aaaaaatgca aaatacatct gcatacatac gacaacatat
    24721 accattagaa ccaatgtttt tttgaatcaa ctctgcaaca tatattaaag ctttatctcc
    24781 tcctctaact ccataaatgt cattaattac cttgaactta tctatatcca tcattataat
    24841 tgcataacgc ttgtcaggat atcttttaag cattaaactt atttgttcac aaaaactttc
    24901 ataattgtat agtcctgtta atgtatcttt ttggttttta tgtagttgca taagataatc
    24961 tatatttttt atagcaacta aaatatgtgt ttgtttctca cctaacttat ttttactact
    25021 aatctttaac atataaatta atgcccaata gtacttttta tctattccta aacgtctata
    25081 ctcaaaattt agttctaaat cgtcttgctt gctattatta agactatcaa gagattttag
    25141 aaggtggtta tcattaaata atattatatc atcaggatga attaaatatt tttttatgta
    25201 tgaaaaagtt ttttcaagat tttcctttat aggaaaacta aaaatattgc tctctgattg
    25261 ataaattgga gtaattaaat tcgtatcaat gcaaatagat aaaattatat catatgtatt
    25321 ataagctaat ttttcataag ctttagaata cccttttatc attaaatcat caaaataaac
    25381 cttatcaact aactctttat gtttaaataa aatattattc gtcgaatcag ctaagtcact
    25441 aattactttc atttcattat ttctaagttt gttcttatta taatacctct tcttatcttg
    25501 gtacattctc tcatcagcaa ctttaattag cttatgtata tcaatattat cgtcactcca
    25561 aatactgccc actgctacac tatatatcat ctcatcctta aattcttcac ttaaccaact
    25621 cactaattct tcaaatagtt gttttgatat atcttcacat aatacaacaa actcatctcc
    25681 tccaatacgg taaacattat aagaatgaaa gtattttttt attattacac atgctgacac
    25741 aatagcagaa tcgccattag catgtccaaa gttatcatta atatctttta acccatttat
    25801 atctacaaat acaactccta tggatttaac ttttcctttt tgaaaattat ctatatactt
    25861 aatatattta tttctattat atgcaccagt caagaagtca tagtagctca tataatttaa
    25921 tttattttct acttttcttt ttttcatctc agttaataaa aaataagata gggatgtcaa
    25981 aagagaggta tctccaacag ctttatgtgg attatcaact ccaataaacc ctactacttt
    26041 atcatcttgt tttagtgaag atgtcattaa actttcaatt ttttgaggtt ttaaaatttc
    26101 atattctatt ggctgttctt cttttatatt ttctatatca tcaattatta caaaaccttt
    26161 ttgttcgaat aataaaaacc aattctttaa ttcattaata tcaagatttg ttagtgcctg
    26221 tttttgttca tcaacacctt cattgcacca ttcatatgta ttagttactt ttgttctatc
    26281 ttctgatact tcaaaaacat atgctctatc agctttatga aatttaccaa tattggttaa
    26341 tacaagattt acagcatcag aaaaattaga ttctgttata agatgtttaa tacatccaac
    26401 taataactcc tttatctcta atttttctgc tattgactta cttatatctt ccttttctgt
    26461 aatatcaaga gctatttcta atcgtgcatg tttgccctcc catttaatta acttgtcctt
    26521 taatataaaa tgtctatttg ttcgagtatt cgtattttcc catatgtaat attcatcttc
    26581 ttttaaaata gagtttgtac aaaattcgca gggagaatct ttcccctgta atgctttata
    26641 acattttaaa tgggatatat cattaagtcc cattgccttt ttcccaattt cattaatata
    26701 taaaagttca tatgtatcta aagaagaaac atatacaatt tcatccaact catctattaa
    26761 atttattaca tccatttata tatatctcct tttattcatt ttccagattg aatttttaaa
    26821 gcttttaaaa ttttgctata tatttggcaa tgatattata cttctttatg ttttaaaata
    26881 gtaccttaat gaggttctat tttttagtaa atagaattat tattgtgtca atcgtacaat
    26941 agagttttgt aatacttaat ttaatatatt tataattaac tatcttatta tgtatttaca
    27001 attaattctc atataaatga caaatctcca cctcaattaa gtattccaat catatatgag
    27061 gataatactt cattcattta aaaatataaa actattatat attaaaattt cttcaataat
    27121 aaattattta gattgttact ttgatatatt atataatatc acaaaggctg atataaaaag
    27181 acaaaaaggg caattttttt atatcaaaaa aaatgttaaa ttgatattat ccatatagat
    27241 gctatattta acaattctac ttacttccct tacacttatt agcatatagt tattaagaat
    27301 ttgttgcaaa acaacactta gcacacttta aaaagtgtgg tctaataagt aatcaacgaa
    27361 gaagacataa taaagcataa aatatgatat acttttccac gccatcaaaa ctgaggattt
    27421 tattattaat atatgctaaa atatgcttaa taaattaaat tttaatggga gaatagttat
    27481 gaaaatattt agtttcttgt tgtttgtgat aggaatatgt ttatgtattg ctggatttat
    27541 aggacattac ccagtatttg ttggtacaac attgagtttt cttgcaattg caatgatagc
    27601 tgtaagacaa gtcaaaacta agaaaaaaat gaaataggca aatcctaact ttacaagtta
    27661 atattacaca agtaattagt ctaaaattgg atactttttc tattacagaa atacatcatc
    27721 cactttgtat tttcttaaaa aaataaaata gctatgtaaa ttcaagatta gatagattaa
    27781 ctctctatcc atttcattgt aaaatataca tagctatttg tattcgattt aaaatactta
    27841 tattttctta cataacaaat aatttctatc tgattattac tcatattcat ttagtaacca
    27901 ctcagcacct aatcatttag tatctattca tccgccatac ggtaacctac cccaacctca
    27961 gtcaaaatat attctggctg agcaggattc ttttcaattt tccttcttat acttgccata
    28021 aaaactctaa gcgactgatt ttcactttca tagtaatttc cccaaacttt atctattata
    28081 aacttatggg ttaagactct tcctgaatac ttagacatca actcaataat cttatattcg
    28141 attggagtta aatgtatttc ttcaccatta attgacacaa tatgattttc ataatctatc
    28201 tttaggtttt taacttcaaa agactttgga gcatcattat ttatattatc ctgttgagct
    28261 ttatttctaa gagccacacg tactctagcc aaaagctctg ttacactaaa aggtttagtt
    28321 aaataatcgt ctgctcctcc atctaaagct tccaccttat ccctctcatg ctctctcgct
    28381 gaaacaacaa ttattttatt agtctttgca catgccctaa ctcgtcctat tacctcaatc
    28441 ccatcaatat ctggtagtcc taaatccaaa attatcaaat ctgggtcaag agaatgtata
    28501 agtgatatag ctgttcctcc attatctgtc tctacacacc tataattttg agtttcaaga
    28561 gatactttta taaatttaca aattggctta tcatcttcta caattagaac taatggcttt
    28621 atttccactt gtctttcccc tcctcatcat acataggtat gctaaatcta aatgtagctc
    28681 ctccagaagg attattaaag gcgacaattt ctccaccatg agcttctact atagatttac
    28741 atatctccaa tccaagacca atacctcttc tttcaagatt tctagactta ttcttagtat
    28801 aaaacctatt aaaaatattc ccgatatctt catttggtat tccttttcca ttatctgcaa
    28861 cttcaaatag tacttgattt gactcttttt ttacagttag ttctatctta gaatttttag
    28921 gtgtatgcct tatagcatta tcaattagat ttactaacac ttgttctatt aacaatacat
    28981 ccacatgaac gattattatc tcatctggaa tatttgtttt tatgtctcta ctattggcaa
    29041 actttttgac tcttaatata gattcagcta ttatttcatc aacaacctct ggtcgttttt
    29101 caatatccaa ttttccttca tctattctgg tcatactaag tatattctca acagaatgag
    29161 ttagccaact cgtatcttca tatatatttt tcaataattc tactctagtt tctttatcta
    29221 tcacatcatc attttcaagt attgttgaag atgaacccaa tatacttgta agtggagttc
    29281 ttaaatcatg agaaattgac ctaagcaagt ttcctcttaa tctctctctc tctgcctcaa
    29341 gatttgcttt tttatttttc tcaaataaat tttctctatc aattgccaac gcaacctgtg
    29401 ttgaaactgc ttctaatagt atcttttcat tttctgtaat aatatctatc ttaaaacacg
    29461 caacacctat aacaccaaga acatttgatt cttgaccttt tatagggaaa taatatgcac
    29521 tgctgttttt acaatatttt gtcccaattc caactggatt acctgtccta aaagcttctt
    29581 ttatagcttc cttttctaat actgaatgga atatattctc acttccatca ttgttacaaa
    29641 tataaatact tggcttacct agattattat tctcatctgc aatagtcact attacagttc
    29701 tatttaatat atttactaaa ttagacccac aaaattcaat aatttgattt ttattttttg
    29761 ctttaagcaa cgttttgtta ttctcataga gcaatcttat cattttttct ctcttatgag
    29821 aaagtctcac ttctcttttt atcctagaag ttaaagtact tgttataatt gctgccatta
    29881 gcataataca aaaagtcata ggataatctt ttctataagc taaaaaagta tataatggat
    29941 gcgtaaagaa aaaattaaat gatagcactc ctattactga agaaagtatt ccaaaaaaat
    30001 atccataggt tatacttgta gcaaatagta cacctaatat gtatactagt ataatattag
    30061 attcattaaa acctaccttt tcaaaaacta ctgatattcc agtagcaatt gtcataacca
    30121 atatagtttt tatgaagtcc ttaataatta tctttttact gagatagcca tcttcatcat
    30181 aatcatactc ttttaagtct tcatgttgta gtcgttcctt tttcatttac tacaattcct
    30241 ccttattgtt actgtttaaa ttggctctat tttatataat acaattttat cataataaat
    30301 tcaatcaata catttaatta atgtacttaa attactaaaa ggtgctgtct taaaatgaaa
    30361 ataaatctct atttcaaaac agcacctata tatttaaatt actaatttag tttttacata
    30421 cttaaatcaa tagttttatt caatttcata aattataata cttcaattat aaaacatttc
    30481 tatccaacaa gcataaatat aaagtgggca catatacctg cacataaacc acctatagta
    30541 tgcgaaagta tcgctttacc agccaatggt cttgcatcta aagcatccat catacctatg
    30601 tgtgtactta aatatccact ccaacacata cccattgctg tgaatactgc tatatcatta
    30661 ggagttatag cgcctgattt tataaactct ggtactaaag atattgctgc tccaacagct
    30721 cctaatgcag ttacagggaa tgctattgcc tctggtgatg tgaatccaaa taatggttct
    30781 attatgaagc taatcttatc accaatagca ggtaataatt ttataccttc atatgcagct
    30841 cctgtgtaaa cagcttgacc tgtagcaggg tctgtagatg gtccaaaagt taataacata
    30901 actaatgtac aaactactaa aactcctggt attatagcca tacccatttc aacacctaac
    30961 ttaccacctt caagtatagc atccaatgtt ctttggaata cattaccatc tcttatttct
    31021 ctaaactctt caagttttgc acctttatca tttatttgct tttcagtatc atttttaggg
    31081 tcataattat aatacttttt agtaaaagtc aacataattc taacactaat aatactacct
    31141 attattgccc caacattacc tattatagct ggtagtacat attctttacc ttgagctatc
    31201 ataaaagttg ttacaataag tcccatacca aaggctgttc ctaaattaca taaagcaggt
    31261 acttgatact tcttaaaata ttgtgtaaat gttttgtctt tagcaaatgg tataatagct
    31321 ggattatcag ataaatatgt tgcaactact cctgctatac tagcaccagg taagccccat
    31381 ataggtctca taagaccctt aaatatctta ttaactaaag atattactcc aaactctgaa
    31441 agcaatgcac taagtgcacc tgcaagaact gccatagcca ttattaaaaa tactgtgtct
    31501 aataaaagcg catgtgctgt actcattatt actttaaaca tcattcctgc acccatgatg
    31561 cttcctacat atccaaatcc taccgccaat agtacaataa atacgaaggt ttccatactt
    31621 actgccttga ctcttctctt atccgacagc ttttccatct tgaaatcttc ccccttttaa
    31681 ttttaaatta aggttcctaa cattggtaca aattttttgg tacaaactga gttctaaaac
    31741 ttacactcgt aatgcaagtt gtcagttttt tgaaataaaa aaaaattacg tttatagaat
    31801 aagaatatcc tctttaattt ggatactctt attctatttt atgttattat attatcatcc
    31861 ttttgtttaa aagtcaattt tttctatttt tgttgtttaa ttttatttat actcttttta
    31921 tatttttcat tttcttttat ctttgtaagt actccatata agttgacttt tctaaataca
    31981 gtagttataa ataccaatcc taatgcaatt gaacttgcac acgataatgt actcacccca
    32041 tattctacag cttttatata attattggtc aaaacagaat acatagtatt atatattcca
    32101 taaccaggta ctaatattat taaacagcaa acacttaatg tagttgctgg agtcatataa
    32161 attcttgcac ataactcaca gtatatcgca aaacaaactg tagctataaa aaaacataag
    32221 ttttctgtta ctcccatatt taaaagaaat ttatacgaaa accaagctat acttccacct
    32281 attcctgcta gtattaagtt ttttcctttc atattaaata gcactccaaa gcttaaggca
    32341 gtaaaaaaag ctgctattac ttctataaac aaatgcactt atatcccccc taacttgaag
    32401 tacaatccaa gtaccaagaa cattcctact gctatagata cacctacaaa aaatacttct
    32461 gctaattttg caagaccaga aatcaactgt ccatctaaca aatctcttaa tgcattagtc
    32521 aaagcaagcc caggaactaa gagcattatt gctcctgcta ttaaatggtc taacgtcttt
    32581 atgaatccga gctttaaaat taaaattgaa caagaagcta taataactgc tccaattgca
    32641 tttacaaaaa agtcattaag ggaagattta cttaaataca taataacaaa cttagtcaga
    32701 atcccaacag taaatgcagc tataaattct tccacatttc ctccaaataa tatcgaaaaa
    32761 gttgctgctg caatacctgc aaaaaatatt gttattaaat ccgagtaata gttatcttca
    32821 cttatttcat ctaaaatttt ctcacataat tcaatatcta aattatttat acttattgct
    32881 cttgataatg agttaacttc atgaaccaag tttaggtcta ctcttcttga gcttattctt
    32941 ttaattgctg aatgtaattt cccatctaca aatacagatg ccattacagc tgttggagtt
    33001 gcaaatacat ctacgtggtc tattccaaaa gattgacata ttctagctat cgtttcttca
    33061 actctatagg tttctcctcc actttgcaac atagctttac ctgcatttga ggaaaagttt
    33121 aaaattctat ctatatccac aaaacatatc tcccattctt ttatagtatt attcatattt
    33181 taatacaaga tattatttat ttaaactatt ttaaataatt catatccaat atttacattt
    33241 tatgaaaaaa cttgtttttt atgcttgtca aaatcaaatt ttaagcttgt ttacaccata
    33301 aaatggctga attaatattt gacaaacact ttcaaccatt tatataacct tctaaattgt
    33361 ataacttttt actacaaata aaattatatc tcttttaatt ctttctcttg agtatttagc
    33421 ttatagtaac ttcatattta tatatgtaca atataaaaca ttatttttat gatacaaaat
    33481 ataatttgta aatgtatata tgtattaact gtgtatatat aaattattct taaccttatc
    33541 agttttttca catatcttca tctataccga ccatatatta ataaatgata ttacatagac
    33601 ttaagtatat taaaaaactt aaatttagtt atttaacaac ataatactct aatttaatct
    33661 ataaaaatcc atacctaata taatgcaact cttattttaa caccatctat tacacaaaac
    33721 aacatattaa aaagtaaaat acaaaatatc cactataaac cttattttaa tactgaatat
    33781 atattataat atatttaatg tagcttaaat atagtttaaa cataaagaaa ggaaacggta
    33841 tatgctaaga aaagataaag ttctattatc tctacataaa ttatgtgaaa atatgacttt
    33901 aaaagacctt caatcagata aaacaggatt cactacaata gaaattgcta accattcatc
    33961 tcttgataga agtaatacca gtaaagaatt aaataaccta tacaatgaaa aaaaagttct
    34021 gaaaatatct ggtaagccaa ttttatttct acatgctagt attatagaaa atttaattgg
    34081 ccgtactttg aacactgatg aattttctat aaataattgt aatgagctac ttaaatcaag
    34141 taaaaatgac tcagaagata ttttttcaac attacttgga catgattcta gtcttaaact
    34201 acctatagaa aaagctaaat ctgctatact ctatcctcca aaaggtctta atacattact
    34261 cataggacct actggtgttg gaaaaagtac atttgccgaa acaatgtaca aatatgctgt
    34321 agaaagtaaa atcttttctt ctgaaagcaa attcgtagta tttaactgtg ctgaatatgc
    34381 agaaaatgct aacttattat taagtaattt atttggttat gtcaaaggtt cttttactgg
    34441 tgctaataag gataaattcg gcatagttgc acaggctgat ggaggcatat tattcttaga
    34501 tgaaatacac agattaccac cagaaggtca agagatgctt tttcttttga tggacaaagg
    34561 catatacaga cgattaggag aatctgacat tgtgcataaa gctaatgtct ttattgtgtg
    34621 tgccacaaca gaagatatac attcttctct gcttgggact tttttaagaa gaatccctgt
    34681 tacaatcaac ctacctgctt tacaggatag gtctttaaaa gaaagattat ctcttattaa
    34741 atacttcttt attatagaat caaaatacac caatgcaact ataaaagttc acaaagatgt
    34801 aattaaatca ttactccttt atgattgttt tggtaatata ggtcagctta aatctgacat
    34861 acaacttatg agtgcaagag cctttttaaa ttacaaaact ggacttaagg ataatataga
    34921 aatagattta tcccttgttc ctgattacat ctatattggt cttttaaaat tgaatgaaaa
    34981 tcgtagtaat ctaaataaat tatcagaact tgattatatg cttttttatg aatttaatgg
    35041 taataactta gaagttgaat atacaaaaga actatctaaa tacaatatag atacatcaaa
    35101 caatggattt aaatattcta cagagattcc ttatctggaa aatgatataa ggagtatgtt
    35161 tataaattac atggaaaagt actctacaaa attactttcg atatcttcag taactcattc
    35221 tgattataca agtaatgaga tttttaaagt aatcaatcca aagatttact atgctgttga
    35281 acattcttta aaagaggctg aaaaaatatc gagaaacaaa tacacaaaac aaacttatat
    35341 tgctctttca atgcatataa gtgcacttat agaaaatata aatcaagaca catataatcc
    35401 taagtacaat ttatataatg ataaaatttt cttagataaa gatttaaata tagctaaaat
    35461 agttttaagt ataattgaaa atgacttaca aacatcttta cctaaagatg aagtaaaatt
    35521 tatatccatg tttctaaata gcatgtatct tgaaccaaac aatcaatctg aaagtatagg
    35581 agtcataata cttgctcatg gaaattcaac agcaagcagt atgtgtgatg tagcaaattc
    35641 attgcttggt acaaaccatt gtaatgcaat tgacatgcct cttgatgtaa aagtaagtac
    35701 catacttgat aaaactatag agttggtaaa agaatgtgac gaaggtaagg gtgtacttct
    35761 tttaacagat atgggctctc ttatagcttt tggagaactt atttcagaaa aaacaaaaat
    35821 caaaactcgc tcaattgaaa tggtatctac tccaatagtt ttagaagcag taagaaaaag
    35881 tacactacca gaaatgactt tggatgaatt agctaattcc ttaagctctt taaatccata
    35941 tattggacga gcagcaatcg attcaacaga aataaactat cctgaaaagt caagagagta
    36001 tgtaataata actacttgta taacaggata tggttcagct atgaaagtag cagactttat
    36061 aaattcttca cttaaaaata ttagtaaata caatattaat ttagttcctc ataatataga
    36121 aagttttaaa atgtataaga ataaatttag taatactaaa attctggcag ttgttggaag
    36181 tgtagatttt aatgtagcca acaccccttt tatacacata gaggaactac taaatggata
    36241 tggcctagat atgctaaaca aaataataga aggtacattc aatgccaata gtattacaaa
    36301 tataaaagaa acaaatctat catacaacag tttaataata aactttatga cccaaaactt
    36361 agagcttttg gactctgtta aattattcaa ctatgtcaat tcttccttat ttacaataat
    36421 agaattaata gatgaaaact taaagagcaa atttaagcta ggatatatac tacattgctc
    36481 ttttatgata gaaagatgtt ttaaaaatac aacttttcca tataataaca ttactgaatt
    36541 aattagtaaa aatcatgaac tatatagttt aatacgtgaa gcctttaagc caacagaagc
    36601 ttattttaat attttgatac cagacgaaga aattgcttat ataatagaca tgattaatga
    36661 gtatctaaat aaataaaatt tatagcactt attttgtgca tattaattaa tatatgaaat
    36721 ggaggacgag attttgaaag gaaaaataaa acagttaaca atacttgcat taatttttat
    36781 atttataact cctgtatttg catttgcaga tactccacca gtaccaaatt cttcaagagc
    36841 agcactactt atagaccagg aaactaaaag aatattattt gaaaaaaaca ttgatgaaaa
    36901 aatgccatta gcgagtttaa gtaaaatgat gaccttttta ttggcaatag aagcagttga
    36961 taaaaatcaa gttaaagaga ctgatatggt gaaaatagac aagtctacag cttcagtagg
    37021 aggttctact tgtaaactta aagatggtga tgaaatatct ctaggagagc ttatgcaggg
    37081 tctaatgcta gtatctggaa atgatgctgc tatagccata gctaaacata ttggtaaaac
    37141 tgaaaagaat tttgtaaata tgatgaacaa gaaagcagaa gaaataggaa tgattgatac
    37201 gtattatttt aatccaaatg ggcttcctat atatactgac ccagaacata aagaacctcc
    37261 tattgaaaat atgtcaactg ctcacgatat agttacactt ggaaagtata tgtacgacca
    37321 ttatgaaaat caagttacaa gaataaccac tatgcaagta tataatgata ctaaaaagga
    37381 ttttacacat tataacacaa atcctctgct tgtttcagta cctggtgttg atggaataaa
    37441 gacaggatat acagataatg ctggatattg ccttgcattt tctatgatgg tacctaaaga
    37501 tgctaaaaac gaaagaaatc atagattgat aggtgttgta cttggtgatg gtaacaagaa
    37561 aaatagaatt tcttcttccg ctactttatt gaaatatggt aaagataatt tccattctaa
    37621 aaagatagca cataagggtg atattataga gactccttgt gttgatggta ttgatgattt
    37681 taagataaca gttaaggttg ataaagattt gtatggtgtt gtttcagata acgagaatat
    37741 caatcctaag gtagtgttta aaaatatgaa ttatcctatc cataagggag atattgttgg
    37801 tgttgcaaag tattataatg actctggtaa atttgttgga agtgttgatg taaaaagtga
    37861 aagtaatata ggatgtattc ctttgaagga taagattaag attaaggttg ctaagataaa
    37921 taaaaaactt gatattaaaa attctgtttg ttttaaagca tagtaaagca tattattaaa
    37981 agggtatgtt aaatttataa agactccact ttgtggagtt tttttgtttt ttacaaaaaa
    38041 ttaaaatagt ggcaacaatt gaggatgtga gggagagttg ccactatttt gtatagggta
    38101 ttatattatg tttttaagct agttttacta tcttctatgt ttatataata actcttgtgt
    38161 gtgaatttaa ttgataatta atatgaaaat tatgtgaagt ttttaattga tgtaaagtaa
    38221 tagattatat ttagacactt aaaattataa taaaacatct taatttttat atttatacta
    38281 attaattcta gtataaatac ttattaaata cctttattca aacattattt cagatttata
    38341 ctattcttat atgttaaaag gctgtagaaa aattatttta aaaatcctac agccaatact
    38401 agtatcatca agaaaattta catcttatta aactaatttt tattcatatt tcattattta
    38461 ttttaatata ttaaataaac ttgatagccc agaagatatt tttcctattg ttgatattgg
    38521 atctgacaca tgttttttaa cttcaaatgt tacatttgct gctgaatctg tagcagttgt
    38581 ttcagatact gctcctgctt taactagcac acttacatta tctaaatcag tttgtactgc
    38641 ttggcttgct gttcctgata ctgttattgt tattgtattt gctgatctat ttccttc
//
LOCUS       DAEPUT010000037        38468 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.038, whole genome shotgun sequence.
ACCESSION   DAEPUT010000037 DAEPUT010000000
VERSION     DAEPUT010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38468
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.038"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(46..702)
                     /locus_tag="KRL22_001976"
     CDS             complement(46..702)
                     /locus_tag="KRL22_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1272467.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(757..1386)
                     /locus_tag="KRL22_001977"
     CDS             complement(757..1386)
                     /locus_tag="KRL22_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1272468.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(1517..2158)
                     /locus_tag="KRL22_001978"
     CDS             complement(1517..2158)
                     /locus_tag="KRL22_001978"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBH1272469.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(2167..2838)
                     /locus_tag="KRL22_001979"
     CDS             complement(2167..2838)
                     /locus_tag="KRL22_001979"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH1272470.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(2843..3727)
                     /gene="rsgA"
                     /locus_tag="KRL22_001980"
     CDS             complement(2843..3727)
                     /gene="rsgA"
                     /locus_tag="KRL22_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH1272471.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANIDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(3825..4562)
                     /locus_tag="KRL22_001981"
     CDS             complement(3825..4562)
                     /locus_tag="KRL22_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH1272472.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(4670..6685)
                     /gene="pknB"
                     /locus_tag="KRL22_001982"
     CDS             complement(4670..6685)
                     /gene="pknB"
                     /locus_tag="KRL22_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBH1272473.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(6702..7454)
                     /locus_tag="KRL22_001983"
     CDS             complement(6702..7454)
                     /locus_tag="KRL22_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBH1272474.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(7474..8505)
                     /gene="rlmN"
                     /locus_tag="KRL22_001984"
     CDS             complement(7474..8505)
                     /gene="rlmN"
                     /locus_tag="KRL22_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBH1272475.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(8513..9838)
                     /gene="rsmB"
                     /locus_tag="KRL22_001985"
     CDS             complement(8513..9838)
                     /gene="rsmB"
                     /locus_tag="KRL22_001985"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBH1272476.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQNKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(9900..10601)
                     /locus_tag="KRL22_001986"
     CDS             complement(9900..10601)
                     /locus_tag="KRL22_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBH1272477.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(10670..11422)
                     /locus_tag="KRL22_001987"
     CDS             complement(10670..11422)
                     /locus_tag="KRL22_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HBH1272478.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            complement(11432..12361)
                     /locus_tag="KRL22_001988"
     CDS             complement(11432..12361)
                     /locus_tag="KRL22_001988"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBH1272479.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(12376..12816)
                     /gene="def"
                     /locus_tag="KRL22_001989"
     CDS             complement(12376..12816)
                     /gene="def"
                     /locus_tag="KRL22_001989"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH1272480.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(12834..15359)
                     /gene="priA"
                     /locus_tag="KRL22_001990"
     CDS             complement(12834..15359)
                     /gene="priA"
                     /locus_tag="KRL22_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBH1272481.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(15598..16797)
                     /gene="coaBC"
                     /locus_tag="KRL22_001991"
     CDS             complement(15598..16797)
                     /gene="coaBC"
                     /locus_tag="KRL22_001991"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBH1272482.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(16802..17068)
                     /locus_tag="KRL22_001992"
     CDS             complement(16802..17068)
                     /locus_tag="KRL22_001992"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBH1272483.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(17071..17688)
                     /gene="gmk"
                     /locus_tag="KRL22_001993"
     CDS             complement(17071..17688)
                     /gene="gmk"
                     /locus_tag="KRL22_001993"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBH1272484.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(17718..18599)
                     /locus_tag="KRL22_001994"
     CDS             complement(17718..18599)
                     /locus_tag="KRL22_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBH1272485.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLSKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(18603..19433)
                     /locus_tag="KRL22_001995"
     CDS             complement(18603..19433)
                     /locus_tag="KRL22_001995"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBH1272486.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDYVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGVLEV
                     "
     gene            complement(19720..20754)
                     /gene="ltaE"
                     /locus_tag="KRL22_001996"
     CDS             complement(19720..20754)
                     /gene="ltaE"
                     /locus_tag="KRL22_001996"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBH1272487.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            21050..22825
                     /locus_tag="KRL22_001997"
     CDS             21050..22825
                     /locus_tag="KRL22_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HBH1272488.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(23040..24692)
                     /gene="abc-f"
                     /locus_tag="KRL22_001998"
     CDS             complement(23040..24692)
                     /gene="abc-f"
                     /locus_tag="KRL22_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein"
                     /protein_id="HBH1272489.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     MQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYIISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(24991..26202)
                     /locus_tag="KRL22_001999"
     CDS             complement(24991..26202)
                     /locus_tag="KRL22_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBH1272490.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKIVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(26486..27019)
                     /gene="pyrR"
                     /locus_tag="KRL22_002000"
     CDS             complement(26486..27019)
                     /gene="pyrR"
                     /locus_tag="KRL22_002000"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBH1272491.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(27379..28326)
                     /locus_tag="KRL22_002001"
     CDS             complement(27379..28326)
                     /locus_tag="KRL22_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH1272492.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVIEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(28295..28741)
                     /gene="lspA"
                     /locus_tag="KRL22_002002"
     CDS             complement(28295..28741)
                     /gene="lspA"
                     /locus_tag="KRL22_002002"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBH1272493.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(29051..29830)
                     /locus_tag="KRL22_002003"
     CDS             complement(29051..29830)
                     /locus_tag="KRL22_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1272494.1"
                     /translation="MKKIIWGICICLLSVVGVYTYSHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(29885..30367)
                     /locus_tag="KRL22_002004"
     CDS             complement(29885..30367)
                     /locus_tag="KRL22_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH1272495.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(30633..32054)
                     /locus_tag="KRL22_002005"
     CDS             complement(30633..32054)
                     /locus_tag="KRL22_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH1272496.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILALLFSKKAKHIKEQNNHKLAS"
     gene            complement(32200..32970)
                     /locus_tag="KRL22_002006"
                     /pseudo
     CDS             complement(32200..32970)
                     /locus_tag="KRL22_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(32975..34177)
                     /locus_tag="KRL22_002007"
     CDS             complement(32975..34177)
                     /locus_tag="KRL22_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH1272497.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
     gene            complement(34765..35766)
                     /gene="trpS"
                     /locus_tag="KRL22_002008"
     CDS             complement(34765..35766)
                     /gene="trpS"
                     /locus_tag="KRL22_002008"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBH1272498.1"
                     /translation="MSEKKVILSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(35789..36487)
                     /locus_tag="KRL22_002009"
     CDS             complement(35789..36487)
                     /locus_tag="KRL22_002009"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBH1272499.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     misc_binding    complement(36530..36770)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(36861..38264)
                     /locus_tag="KRL22_002010"
     CDS             complement(36861..38264)
                     /locus_tag="KRL22_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1272500.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
BASE COUNT        12296 a         7057 c         3918 g        15197 t
ORIGIN      
        1 ttattttgtt tttaatttac ttcgatttta aaatgtcctt gacttttatt ttataaatgt
       61 acatatttct tctactggtt ttttagatgg actcttcaaa ttgtcctctg gcactccaag
      121 agctaacatt gcacctaaaa aatactctcc cttttcaaaa ccagtttctg cttctaaaac
      181 agcttctatc tcatctgctg catagttttg acttgtcaac caacaagaac catatccaag
      241 ttcaattgct gatagtgtaa agttttcaat tgcagcacct agactctgca tacctggatt
      301 tcttataaat aatttatcta tagtctcctt aggtgcatct ataagctcta attcataata
      361 tcctgatgga ttatatacct ttgtaaaaac taatactaaa actggagctt ttaagtaaaa
      421 tagtgtaaaa tttttaacaa attttctaaa tctattagcc ttatccactg atactttatc
      481 catttctaca agtatttctt gttgcttttt agttatcaca tctgctatct tttccattaa
      541 atcacggcgt tttataacaa caaaatgcca gttttgaata ttcttgcctg atggtgctgc
      601 acctgctgct tttatcattt ttaaaatatc ttcatctgat acatcttgat ttttaaattt
      661 tcttacactt tgtcttttaa aaatagtatc ttgtaattcc atttttaaat ccccccataa
      721 cttttttatt attttaatat aatttttaaa ctcatcttat tttaatatat catgttctaa
      781 caaatcttta aatgagtcta taaaataatc atatacatct acattcccaa acccatattt
      841 ggcatatata aaaggtatac ctacaaactt agcactattt gcatcacctt gcgtatcacc
      901 aacatagatt ggatttatta atttatttct ttcaattata agtttattat tttctccttt
      961 atgcaaacca gtattaccag gacattcaaa atctataaaa tactgttcta gtttatgtgc
     1021 ttttaaaaaa gattctatat atccagcttg acaattactt actataaata atttatattt
     1081 tttagatagt aatttaagag tatcttctat atcatcaaat aatttagctc cattttcaga
     1141 taaatagtca cattctttca aagaacattc attcaataaa ttcattcttt cttcttcact
     1201 taaatttgga aataaacgat ttgctatttc ctcaaaagaa agccccataa gacttctaaa
     1261 taaatctttt gtgacactta attctatttc cttatgctca cttaaaacat cctgccagac
     1321 tttgcatact tcttcagttg aatcccacaa tgttccatct aaatcaaaaa taatactatc
     1381 taccacaaaa aatccccctt atgtcaaagt ttattatcta tttataatta tatactaaaa
     1441 agcagataca atcataaata tattttactt gattgtatct gctctacaat ataaaaccaa
     1501 ttgtcaaaat caaattttat aaatttctaa ctacaagtac acagccttgc tctactttaa
     1561 tcttacaaga attactcaac ataacatttg atattccaat aggtacagag tatttcatat
     1621 aataattatc gagagggtat tctaagccag taagtgttac acccttagca tcaccattta
     1681 tagctattac agaaatagtg tcccctgggt ttccatacaa tgaaatttcc tcattttcaa
     1741 ctatatacat ctcttcttta tcagaaagta tcctagaata tataccatct tcttttaaat
     1801 aatataatag ctttatattt gcaagagtgt ggtcaatcct tccccctaaa gcaccaaaaa
     1861 aatcaatatg atttgcttta agtgtcttag ctaaaaaaag acaaagctct gtatcagtct
     1921 catctttttt agatggaaat ttttcaaatt taacaccttt atttttatag aagtttatct
     1981 tttcttcttc tactgaatct aaatctccta atatataatc tggcattatt tccattttat
     2041 aagtgtgatt tgcccctcca tctgcacata ttatgcagtc ataacattcc ttaattataa
     2101 tatctcttgt aacttcgtaa tcttcaattt cgccatttaa aacaatacag attttcatta
     2161 ttaaatttaa actaattctt caagagaagc attctttcta aataaattaa ctgtttcttg
     2221 aatgtcatca cttccaaata ttgcagaacc tgctactatt acattagctc ctgcttgtac
     2281 aacttcggct acgtttttag ggcttatacc accatcaact tctatatcaa tgtttaatcc
     2341 ttgactatct ataatagctt ttaactcttt aatcttatct aaaacacaag gaataaatga
     2401 ttgtcctcca aatccagggt taacagacat taataatacc atatctaaat caggtagtac
     2461 atgtttaatc gtatctactg gtgtagctgg attaagtact acaccagctt ttattccatg
     2521 tgattttata ttttgtatag ttctatgtag atgaacacaa gcctcctggt gaacagttat
     2581 tatatcacat cctgctttta caaattcttc aatatactgg tctggatttt ctatcataag
     2641 atgagcatca aataccatat ttatattttc tttctttaaa cttttgacta caagtggtcc
     2701 taatgtaatg tttggtacaa agtgtccatc cattacatcg atatgaagat attcacatcc
     2761 tgcactttct acttttctta catcttctaa taattttgca aaatctgctg ataatattga
     2821 tggtgctaat ttaatcatgt ttctaatacc tcctactatt attttgtctt atttcatgta
     2881 gcagctgtat ataactatca tatctttctt tagatatttc tccatttgta acagcttctt
     2941 ttatagcaca attaggttca ttttcatgaa tacactttga accaaactta caatcattaa
     3001 atttatcaaa ttctataaaa taatctttaa gttcaacttc ctctatatct tcaagggcaa
     3061 gggaactaaa acctggtgta tctgcaacca ttccaccaaa ttctaatttt aaaagttcag
     3121 cgtgacgagt agtatgtttt ccccttttta ttttatcact tacaactcct gtttgaagtt
     3181 taaaattttc atctatttca tttaataagc ttgattttcc aactccagat ggtcctgcaa
     3241 acactactac attttctttt aattcttctt ttactttatc tatatttaac ttagtaatat
     3301 tacttacagg aatgacttta tagccactaa gttcatatat atttttaaca gtttctaatg
     3361 tatcattatc atctaaatct gcttttgtaa ggattattac agtttctaaa ttttcttttt
     3421 ctgccaaaac tataaatcta tctaaaagag ataagtttgg tttaggattt tttattgcga
     3481 atactattaa tgctttatct atatttgcaa taggaggtct tataagttct gtatctctac
     3541 tgtcgatttc ttctaagata cccttttttt catcttcatc aacaatgctt attttgactc
     3601 tatcaccaac caaaggtgtt attttctgct ttctaaatat ccctctagcc ttacattcat
     3661 aaataccatt ataagtatct acataataaa atccactaat cccctttata atttttcctt
     3721 ctagcatcaa atgcctccct ttataaaatt tatataaaca catactgttt atgagtagta
     3781 tatcgtgtta ttctttccta tttttatata ataccacatt ttttttaaat aacaaatcct
     3841 ccgtttggac taattacctg accagtgata aaatttgatt tgtctgatgc caagaaaata
     3901 gcacaatttg ctatatcttc tggagttcct agcctcatta gaggggtttc ttccacaaga
     3961 gcgtctatat cttcctcatt atatccagat aacatgtcag tattaatgac acctggagct
     4021 atgctattta ctctaatatt tgatggtcct acttctttag ctaatgcctt tgtcatgcct
     4081 attatgcctg cttttgttat agaataatgc acttcacaag aggcacctga tataccccag
     4141 attgaagata tattaattat atttcctttt ttttctgata tcatgtattt taaagcaact
     4201 tgtgaacaat aaaagcttcc ttttaaatta atattcatca tattatccca atcttcatca
     4261 gttatatctg taaacaactt atcttgactt acaccagcat tgtttacaag tacatccaat
     4321 cctccaaatt cttttataca ataatctacc atatcctcta catcttctct atttgaaata
     4381 ttagccttaa aaagttttac agaaaaattt ttttcattta atatagtgta caactcttta
     4441 gcttcatttt ctgacttatt aaaatttact aatacattgt aaccttcttt tgcaaaagct
     4501 ttagacatag ctttaccaat ccctctagct cctcctgtaa ttaaaactgt tttcttcttc
     4561 ataaatactt ttctccttat attataacca attcagtatt ttatacaaaa caaactgccc
     4621 tttaaagaaa atattttcta taaaaggaca gctcttattt tattaatatt tattctgttt
     4681 taccaatgtt tgcgccagtt cctgatgaag ttcctccatt atctcctgag tttgagcctc
     4741 ctgaactatc tccattgtct cctgagtttg aacctcctga acttcctcca ttgtctcctg
     4801 agtttgagcc tcctgaactt cctccattat ctcctgagtt tgagcctcct gagtttccac
     4861 cactatttcc tgagtttgaa cctcctgagt tacttccatt attgcctgag tttccaccac
     4921 tatttcctga atttgagcct cctgaatttc caccactgtt tcctgagttt gaaccaggtt
     4981 ctgttggtgt attattctct ggtgttgttg gttttttatc tggtactgtt ggagtctgtg
     5041 tatttgattt ttctgaacct ttgcttacat ataggtttac ctcatcacct tcctgagctc
     5101 ttgatgagcc agcacccgga ctctgactta aaactgtacc ttctttatat attgagctgt
     5161 attcatactt aacagttccc acttttaagt tattttcttc aataagttgt tttgcattac
     5221 tcaaagtaag tcccactaca ttaggaacag atgcctgact tgaaccttta cttacgacaa
     5281 catttatagt atcacccttt ttgacatttg tacttccacc ttcaggtgtc tgtgatatta
     5341 tacaattttc atcaacttca ctattatact cttcactttt tacactcagg tataatcctt
     5401 ctttttcaac agcactttga gcttcttcta atgtcatatt tacaagatta ggaacagtca
     5461 aagatttatt gccaaaccct ccagcaaata aaaacttata tgctaagaat acttgagcac
     5521 acaatatcag tatcaaaaca gccgcaatta cttttaatct tcttctagat tttgggcttt
     5581 cctgtttttt cttctttttc ttagttctct tacttggagt actcttaggt ctctgattct
     5641 ttttagctct cattatctct tcctcttctt catcttcatc atcatcttct tcataaaaat
     5701 catcatagta atcttcatca tcatccaaat cagctacttc aacaggctta accacttttt
     5761 caggagctgg ttttgcaagt gttggattta caactttatt aatttccttt tcatcaattt
     5821 tcttagttgc aaaatcatca tattctttta taaaatctaa atcaatattt ttttctatat
     5881 actctatatc ttctatcaat tcttcagcag tttgatatct atctgcacta gatttttctg
     5941 taagcttttt tattgtagtt cttacacttt gaggaatcct aactttttct tctgatgtaa
     6001 agtctatatc atcattaatg tgttgaagtg ctatagaaat tggactatct cccctaaatg
     6061 gaacttttcc tatcaacatt tcatataaaa ctatacctag agaatacagg tcagcattat
     6121 tagttacaaa tttaccttta gcttgctctg gtgaaaaata atgcactgaa cctattatac
     6181 taccaatatt agtcattgtt gaatttgaaa cagctttggc tataccaaaa tcagccactt
     6241 ttactactct tccttcattt gatatgagaa tattatgagg ttttatatct ctatgtataa
     6301 tccccttttt gtgcgctgca ctaagtgcca tagctatttg ttttgttata tctaatgcag
     6361 tatattcatc taatatacct tcatcttgta taatctcttt tagattcttc ccatctacaa
     6421 actccattac aatgtagtga acttttccat cttcaccaac atcataaaca tttactatat
     6481 ttggatgtga aagacttgct actgcttctg cctctctttt aaactttgtt agaaattcat
     6541 catcatctac aaattcaggt ctaagtactt taagtgcaac agtcctgttt aataatctgt
     6601 ctttagcctc atatacaaag gccattcctc catcaccaat cttcctgatg atttcatatc
     6661 gatttcctaa aattgtatct cccacaatat caccgtccta attatacttt tatcactata
     6721 accgaaacat tatctttacc agaaacatca ttggccatac ttatcaattc ttcacttata
     6781 ttactagttc tctcatattc ataatctaat attaaatctc ttatatcttc atcatcaata
     6841 aacccagtta atccatctgt cgcaagaagt attatatcac tttttttgat ttctttctta
     6901 aaaatatcta caacaaccat atcatctgtt ccaattgctc tagttattct attcctctgt
     6961 ggatgtcttc ttgcctcttc ttctgtaatg acatgggcca tcataagttc ttcaaccacg
     7021 gaatggtcta tagttatttt atcaaatttt tcatctgtta acaaataaca tctgctatct
     7081 ccaacatttg ccacatataa gacattatta tacactatag ccgtaactaa tgtagttccc
     7141 attccttcaa attctatatc ttccatagat tttttgtgca caattgagtt tacattatta
     7201 taagcctgtt ttaatatatc atctatatag tctattttta cattatcatg ttgtaataag
     7261 ttttccttta gaaaatcaat tatattttct actgctaatt tactggcgac ttcacctttt
     7321 ttatgtccac ccattccatc agctatggca aatatcccta ttggaccatg ttctgtatct
     7381 ataacttctc cctcacaata gtcttcattg ttttttctta tttttcctat atgggaggca
     7441 caactataaa ccatacgact tcctccttac aaattacttg tattttcttc tcaattgccc
     7501 acaagctcca ctaatatcag aacccataga catcctaact gtggcaggta tattgttctt
     7561 ctccaaacta tccctaaatt tataaataaa tgctttatct ggtttttcgt attctctttc
     7621 ttcaacttta tttattggaa ttaaatttac atgacatagc atacctttta ggagcttagc
     7681 taatgccttt gcttcttttt ctgagtcatt tacccctttt ataagagaat attcaaatgt
     7741 aacccttcta tttgtctttt ttatataata tctacatgca ttcaatattt cttcaataga
     7801 ataagcattt gctacaggca taatttttct tcgttcttca tcatatggtg aatgaagtga
     7861 taaagctaaa tttatagcta tttctaagtc tgccaactca tacattttag gtactattcc
     7921 acaagttgaa agagttatat gtctataccc tatattaaga ccattttttt cgttaattat
     7981 ttttaaaaat tgttttgtat tttcaaagtt atcaagtggc tcaccactcc ccatcaatac
     8041 aagatttgat accctcttac cagtatcttc ttgaatttta ataacttggt ctaaaatttc
     8101 ccatggctct aagtttctaa ttaatccatc cattgtagat gcacaaaaat tacatcccat
     8161 cctacaacct acttggttag aaacacagac agtaactcta ctatcataat ccatcatcac
     8221 agtttctatt atatttccat catctaataa aaacaaatat ttttttgtat tatctacctt
     8281 agattctaac tttaattcta tatctatatg ccctatacat gaaacctctt ctaatttatt
     8341 tctcaaactt tttggtatat tgttcatatc atcaaaagtt tttgcaccct tatatatcca
     8401 agagaatatt tgacttcctc taaagggctt ttcatctata gttttcataa attctttaag
     8461 ttcatcttca gtaaaatttt ttaatactat ctttttcttt tccattctct cactacctta
     8521 ttctctttaa ttttgctatg aaaaaaccat ctataccatg aatattagga tatatcttta
     8581 aatatccttt atcttgattg tctaagtcta catttactgt atcaattgga acaaattcaa
     8641 agttgtgatt ttcttcaaca aaagaagtaa ctatatttat attctccaca tcttgaattg
     8701 tacatgtact atatactaaa gttccaccaa ctttgacata tttagatgca ttttctaaaa
     8761 ttttattttg tatagaagtg atgtctttta actcttcttc tttcttatac ttaatttctg
     8821 gtttacgtct tattatacca aaaccagagc aaggaacatc tgctaaaaca taatcaaatt
     8881 tacttatact attttcatca atctcagaag catcaaatct ttctacaaac acatttttaa
     8941 gtcccaatct atttacagta gagtttataa gctttagttt atgctcaaaa atatctctag
     9001 ctactacttg accagtattg ttcattaaag tagctaagtg agtagatttc cctccaggag
     9061 cactacatac atccaaaaca aatgaacctt cttttggatt aattactttc cctactatca
     9121 tagaacttat atcttgaatt gtaaataaac cagccttaaa taattcattt ttttctatat
     9181 ttttcatttt ttcgacttta atagcttctt ctaccatagg aacttttaaa catacaatac
     9241 ccatttcact taatttttca ataagctctt ctctacttat tttaagtgta ttcgttctta
     9301 tatagatact aggcttttca ttatttgctt ccaacaaatc ttcagcaaat tcttgtccaa
     9361 atttatctat ccagtttttt ataatccaag agttatagga atactttata gataagtatt
     9421 ttacactatc ttcctcagtt atgtccatta tagtctcttt agctcttatt tcatttctaa
     9481 gaatagcatt tatgaaacca gaagattttt tatcatattt cttagataat tttacagttt
     9541 cattaactgc tgcataatct gatatactat ctaaaaataa aatctgatat gttcccattc
     9601 ttaaaaagat tttaacataa gttgacattt tttttacctt tatttttgaa agtttattga
     9661 ttatataatc taaataatat ttattttcta ttactccata aattaactct gttgcaagtc
     9721 ctctatccat atcacttatt tctaaatttt taaaatgctt atttattgca atatttgaat
     9781 aattgtcatt tttttctata tcacataata ctttaaatcc aacttctctt gcatccatat
     9841 aaatttctcc cttttattaa acataaaaaa gggttgtttc taaacaaccc actttacttt
     9901 tagtcatttc ttctttgagc tattagtaac aatctaagta attgaagtat tgaaaccaat
     9961 gctgctgcaa catatgttaa agctgctgct gaaagtactc ttctactttg tcttgactca
    10021 ctttcatcta taatccctaa attcccaagt tgaacgattg ctctacttga agcattaaat
    10081 tctacaggca atgttattat ttggaataac actgaagccg aaaacaatag tataccaatt
    10141 tttaaaaatg gaccagccat aataaatcct aaaaatatta aaaaccaaga tatacttgaa
    10201 gcaaaattca ctactggtac taaactactt cttatttgaa gaggtgcata acctttagca
    10261 tgttgtatgg catgaccaca ctcatgtgca gctactgcaa cagaagttat agatgttcca
    10321 taatatacat cttctgacaa ccttacagcc tttcttcttg ggtcataatg atcacttaga
    10381 tgccctctaa ccatttctat ctttacatca tacaaaccat ttgaatcaag tactcttctt
    10441 gctgtttgct ctccagtata tcctcgacgt gtatttactc ttaaatactt atttgttgtt
    10501 gaactcactt taaattgtgc atatatagta agtaatatag ctggaattaa tacaaccatt
    10561 gttgggtcaa atccccaaaa accgccatat acagggtaca taaataacac tctcctaaaa
    10621 tatattttta ttatacatcc tcttaatatt cacttaactt aaaaacagtt taattacaaa
    10681 ctaatatatt ttttcctgtt aaaaagccta tagctttttc aatatccatc atgtctacat
    10741 tagtatttac acaaggtcca ttaggtcttt tgttaaatac acctaaaaca ggaatttttt
    10801 taatatcttg tattccagat gtcaaatctc tttcacatgc aacagctaca acagctttag
    10861 gtttagtgtc cattataatt tttctagcta gagttcctcc tgtagctaca aatattttta
    10921 cattagtttt ttcctttagc ttaattaatt ctcctatgtt gcatcttcca cattctttac
    10981 aattatctat atcattagta acttttaatt tacaactatt ctcttgaata caatgaggta
    11041 ttaaaattat tatatcctct ggattaaaat tatatttatt actgtatata tattcattat
    11101 ttaactttat atatattctt ctaatatcac tttttgacat accaaatgat gatgcaatga
    11161 aagatataat aggaaataat ccactgacaa tattaaaatt tattttcatt atatttgagt
    11221 taacatactt tcctttaatt actctataag taactgctgt tgaacatagt attataagta
    11281 ttagtgatat tattataata tttatcatca aggagaatat ttgagttaaa cttattataa
    11341 aaaaattaac aactcctatc aaaattccta atattaaaat caaaatccca acacttgtta
    11401 aatacttctt tatatctgtc atacttttca cctaacccaa tactaaacca gtttctatag
    11461 tattcccttt tatatattca ccaaccaaca ttctcttttt attcggcatc tgaatttctt
    11521 caattaaaag tacattatct atagtactta cttttatccc atctttgctt acatcaatta
    11581 ttgtacctac atcttttgtg cttttttcat ctaacacttt agttttccaa actttcatta
    11641 tgacatcatt ataggtagta taagcacttg gccatggatt tactcctcta actaaattgt
    11701 gtatttctct agcacttttt gaaaaatcta tgttacctaa tgatttattc attattggcg
    11761 cataggaaaa ttcttcatga ttttgtactt ctcttggagc atttccttct tcaattaatc
    11821 ttaatgtttc ttttaaagtt tctgcgccta tattcatcat tttatcatga agttctcctg
    11881 ctgttatatt ttcatcaaga tttacttctg tctttagtat catatctcca gtatctagcc
    11941 cttcatccat atacatagtt gtaacaccag tcttttcttc accatttatt attacccaat
    12001 ttataggtgc cgcacctcta tattttggaa gtaaagaaac atgaacattt atacatccaa
    12061 gtttaggaat ctctaatatt tcttttggaa gtatctgtcc aaaagctaca actactatta
    12121 catctggatt taaagattta attttatcta taaattcttt atctctagcc tttactggtt
    12181 gatatacagg tatattattt tcaattgcca gttcttttac tggactcata cctagttttt
    12241 tacctcttcc ttttggttta tctggttgag ttacaacacc caatatttca tacttctcat
    12301 ctattatttt ttgtaaacat ggaactgcta tatcaggagt tcccataaat actattttca
    12361 tcaaatcaac tcctactact tttctatttt gtcaacaaat aaaattccat ctaagtggtc
    12421 tatctcatga caaaatgctc tagctaaaag ttcttctccc tctaactcta ttgtttcacc
    12481 atttctattt aaagctctga cctttacata atttggtctt ctaacatttc ccgcttctcc
    12541 aacaacactt aaacatcctt cctcatctat ttgctcccca gatgtttcta ttatttcagg
    12601 atttataagt tctataagct cttctccaat atctattact actactcttt ttaatattcc
    12661 aacttgaggt gcagccagtc caacaccatc tgcatcatac atagtttctg ccatatcatc
    12721 taataattgt attatctttt catcaatttt ttcaaccttt tttgattttt ttcttaatac
    12781 tggttctcct atttgaacta tttgtcttaa agccattata attcctccta aatttataat
    12841 acactgtttg gattaatatc tatagataca ttgatattct tatcaaatat caaatctcgt
    12901 tttgttatac atatatattt tattataccc tttaagagat taatttcaat attttcatct
    12961 ttaaagagta tttgccatct ataattttga tttatttttg atattgaaca tggatttgga
    13021 cctaatataa atcctaaatc atttataccc cttttttcta ataaataaat caatgatgca
    13081 tgcatatttt ttatattttt tatcactaat ctttcatctt caccactaac aactacactt
    13141 aacatattat taaaaggaga atatccaaat gcttttctta tttttatctc atcttcataa
    13201 aaaccctcat aatcatattc aatagcatgc ttaatagcat agtgttcagt gtcataagtc
    13261 tgaagtacta cttttccctc tttatcagct ctccctgctc ttccagagac ttgagttatc
    13321 aattgaaatg tagtttcaaa acttttaaag tctggaaaat ttaatatcat gtctgcagac
    13381 aaaataccta ctaaagttac attctcaaaa tccagccctt tacttaacat ctgtgttcca
    13441 ataagtacat ctgcttcttt atctttaaat ttatttagta tctcatctaa agcacctttt
    13501 tttgaagttg tatctttatc cattctcaaa gtttttatat ctggaaaaat atattttaat
    13561 tcctcttcaa ttttttgagt tccaactcca aatggcttaa cataagtact tttacattca
    13621 ggacactctt ttggaatttc tttctcatat ccacaatagt ggcatcttcc agtattgctt
    13681 ttcttatgat aagttaaaga tatatcacaa ttttcacatt gaaacacata tccacacttt
    13741 ctacaagata caaaatttgc ataacctctt ctgtttaaaa atagtattac ttgattattt
    13801 tcttcaatcg cataacgtat ttctttttgt aatttcaaac taaatatact tctatttcct
    13861 ttatctaact catctttcat gtctaccact tcaatgtttg gaagaggctt atcatttgct
    13921 ctacttttta tatttataag tttgtattct ccagattttg ccctataata ctcttcaatt
    13981 gagggcgttg ctgaacctaa aataagagtt atattatttt ttaatgccat aaatctagca
    14041 acttctatag cattaaattt tggattcttc tcagacttat atgatgactc atgacattca
    14101 tcaattatta ttaagcctaa ggaattaaaa ggtgcaaata aagctgacct agctccaatt
    14161 aacactctta ctttacctgc tttgacagct ttgtaaacat catgtttttc tccttcagat
    14221 agtttactgt ggaacactcc aactaaatct ccaaacctac tctttagcct atctattgtt
    14281 tgaggagtta atgctatctc aggtactaag aatatactgt ctaagccttg atttagagca
    14341 aattctatta tttccatgta aacttcagtt tttccacttc cagttactcc atgaattaag
    14401 tatggttttt tatcatctac aaacatattc gactttatct catcaactgc ttcttgttgc
    14461 tcattgttta attttatact ttttagtaca gatttgtaaa tactttttgg ctctctataa
    14521 taatccttaa attctagggt tattagcttt ttcttactta gagaatttat actttgtttt
    14581 gaagcattta ataaatccaa taaatcattt atctctacat tttcattatt tttaagaaaa
    14641 cttaatatct ctttttgttt acttcccaca tttattttat tttgctctat ataatcgtca
    14701 atcttatcac tttctaaact caaagatata taacatacct tcttttcatt tttgtgattt
    14761 ttatattccc aacataattt tataattcca tttttattca ttgtgtacaa agaactattt
    14821 aagtttggta tatattttaa cttatcaacc ttaattttac ctttactatc aatcactttc
    14881 tctactattt ctctattttt atcacttaaa gttgatattt tttccttcaa ttcaatatca
    14941 tttaatccac ttaaactttc acctaatagg actactttat aattatttaa cttgtatccc
    15001 tttggatata tcaaatttat acattctata taagtacaca aatatctatt tttcatccaa
    15061 taaaccaact ctaaatcttc ttttctaaat atcggatttt catctaatat atcaataatt
    15121 tcttttattt ttattttttc atctaagcta tctgtaaatt gaaatacaaa ggcttctgtt
    15181 ggtttattac cttttccaaa tggtactaat attctgtgcc caatttttat tacatcagat
    15241 aaaaatacag gaatttgata tgtaaataaa ttatctgtat atatagtatt acttctaact
    15301 attacctttg catatttttt cattataaaa cctctactta aatttaatat attgttcata
    15361 ttttaatata ctttacaaga tattaaaatc tcagaattta taagcaattt caagttatta
    15421 atattaactt tattttaata attaactatt aattatattt tatactttat gacaaaataa
    15481 atgctgaaaa ctacaattta actgacattt gcgagttttt actcgctaaa attaaattgc
    15541 agctttcagc cactttagct gtgataaaat acacaaatat catatttaaa aaaggtctta
    15601 tttctcaagc aacgctttaa ctttatctaa aataacattg gctacttctt cttttttcat
    15661 cttaggatac tcagtaatat ttccctctac atctattatt tttacaatat tagtatcagc
    15721 tctaaaacca gcaccttctt tagttaaatc atttgccaca ataaaatcta aatttttctt
    15781 ttttattttt cctttggcat gttctataag gtcattagtt tcagctgcaa atccaattag
    15841 tatcttatct tcttttattt ttcctatttc ataagcaatg tcataatttc tacttagttc
    15901 tattgataaa tcatcattct tctttttaat ttttttgtca gaataagttt ttggtttata
    15961 atctgcaact gctgcacttt gaattactat tttattttca cttaaatttg atactactgc
    16021 ttcatacaaa tcttgtgctg actctatttg aacaaatttt ttaagatttt gtggaataga
    16081 aagatttgta ggacctgata ttaatgttac atcagcacct ctagctatag cttctcttgc
    16141 tatagaatat cccattttac cagaagacct attagttaaa tatcttactg ggtctatact
    16201 ctctacagtt ggaccagctg taactatcat actttgacct tttaaatctt gctctttagt
    16261 aagattagtc aaaacttcct ctactattat atctggatta gctagtttac ctgttccaat
    16321 atctccacat gcaagccttc cactttccgg ttcaataaat ttatatccaa agctctttaa
    16381 agtttgtata tttttttgaa caattggatt ttcatacata ttagtattca tagctggtgc
    16441 tataagaacc tgtgcttttg ttgccataac agtagttgtc aacatatcgt cagctatacc
    16501 atttgcaatc ttgcctataa catttgcact tgctggcact attaagaata aatctgcttt
    16561 ttttgctaat gatatatgtt caacttccca agtttttggt tcttcaaaca tatcttctac
    16621 tacataattt tgactcagcg attgaaatgt aagtggttta acaaattctg ttgctgattt
    16681 tgtcattata acatggatat ttgcatttag tttttttaac ttacttacaa catcacaagc
    16741 cttatatgca gctataccgc cacttatgcc aattacaaca gttttatctt ttagcatgac
    16801 cttactcctc ttctgaaatt tgttggtgtt gctcagcatg atgtctagct tcttctatct
    16861 ctatttcctc ttctgtcaat aatctatatg ttatttttcc acttgcaact tctttagttg
    16921 ctacacatac aggcttttcc ttagttttat ttgaaacata tggttcttct ccatcaatta
    16981 attttcttgc tctctttgaa acagtcccta ctaaatagta tctgttgtct attttttcta
    17041 gtacctcatt gatagatggt tttaacataa ttataattcc tccttaaatt tctctattat
    17101 aatattttta tatctgctaa ctttattctt ttcagatgat attatacctt ctatttcttt
    17161 agcagatgtt tttacatctt cattaaatat aaaataatca taatccttaa tcattttaat
    17221 ttcttcatat gcacagctaa atctcttctc tatttcagct tctgtttctg tacctcttcc
    17281 aacaattcta ttttttaatt cttcaagtga tggtggtagt acaaatataa atactccctc
    17341 tgggcaaact tcttttattt gttttgctcc ttgcatttca atctccagta atacatcttg
    17401 tcctttttct aaacattcca ttattgccgc ttttggagtt ccataaaaat tatcataaat
    17461 ttgagcatac tccaaaaact cacctttttc tatcatctct tcaaactttt ccttacttat
    17521 gaagaaataa tttactccat caacttctcc agttctgggt tttcttgtag tagctgatac
    17581 agaaagtttt attgtatcat tttctttaag tagttctttg caaatagtac cttttcctgc
    17641 acctgatggt cctgatacaa ctagcaataa tccttttttc acaaacattt aagcattccc
    17701 cttctaatat tgtattctta ctctatattt tgtatttgtt ctcttatttt ttccaattcg
    17761 ctttttactt ctactactaa attagttata tttatatcag atgacttcga acctatagtg
    17821 ttagtttctc tattcatctc ttgtattaag aaatctattt ttctacctat agagtcgtct
    17881 ttaaatatag tatttttaag ttgccctata tgacttttaa atctaactat ttcttctgtt
    17941 atactgcttt tatctgcata tattgcaact tcttgtgcta atctattctc atctattata
    18001 cttgggtcat ccagtaattc acttattctc aaattcaatt tttctctata atcttctaca
    18061 acactacttg aatatttttc aatctcttct atatgatttt ttaataaatc acatctcatg
    18121 gcaatatctt cagctaattt tttaccttct tcacttctca tttctcttaa tttgattaat
    18181 gcatcttcaa ctgcttgatt caacattgac cacaataaat cttcatcttc ttccttttct
    18241 tctattttca caatatcagg aaactttgca acattcataa cgctaatatc atctataata
    18301 tcaaatttat tttttatttc ttttagtatg tctatatact gagatgctaa tccctcatca
    18361 aaatttaagt ttacatcttc tttgcttaat aagtcaaact ttatgtataa atctactctt
    18421 cctcttttta cataattttt tactaaattt ctaactttat cctctaaaaa tgaaattttt
    18481 cttggaagac gtatgtttat atctgaatac ttatgattta tcgttttaca ctctactaaa
    18541 aagtaataat tatcatcctt gtattctcct cttccaaaac cagtcatact tatagccatt
    18601 aattaaacct ccaaaacacc ttcacatatt tttactgctg gacctgtcat ataagagaaa
    18661 tctcctacat ctattttaac tgttccacct tgagacgtta catttacact actttctacc
    18721 atattaagta aattgcacac tattgctgat gcagtcatac cagtaccaca acctaaagta
    18781 tatccacaac ctctttccca agtataaaca tgtatattat acttatcttc tacctttaca
    18841 aaatttacat tcgttttttc aggaaatatt ttattatttt caatctcttt tccatattta
    18901 caaacataat ctacatctaa ttcatctact ataactactg tatgaggaac ccccatcaac
    18961 atagaagtaa ctttaagctc cctatctaaa acctttatac tttcttgcac aaaacgttct
    19021 ttatttgtaa gtacaggaac gtctttagct ataaaacttc cttttcccat attgactctt
    19081 atagagttta tttctctatt ggtaagattt atttttatat cttttatacc atctaatgta
    19141 tctactgtaa aactttcttt tttaactata caattatcat aaacaaattt acaaaaacat
    19201 ctaaggccat ttccacacat agctgctctt gaaccatcag aattataata taccatttct
    19261 acatctgcaa cttttgaatc tttcacaact aacaatccat ccgctcctac agaaaatctt
    19321 ctatggcata ctttttttgc taaagcagta taatcagatg gatttatctg gtcgaatctt
    19381 ccatctattg ctataaaatc atttcctatt ccatgtagtt tccaaaattt cataagtatc
    19441 gctccttcgt aaattaacgc ttaaactatt ataacataaa aaaattccca taaacttata
    19501 atttatggga aaagttttgt aatgacaact ataatttgag gatgtgaggg agagttgcca
    19561 ttacaattag ggtaattata ttatgttttt aagctagttc tttctatgtt tatatattaa
    19621 tatttctata tgaattttat gtatgtttta tttaaactgt ctatgaattt tttaattaaa
    19681 catctggtaa ctagctataa tccttctagt agatatctat taacatacac ctattaattc
    19741 tttaagtgtt tttaaaacat agtctaaatc ttccttagta atatctacat gagttacaaa
    19801 tctatattca ccattttcca ttttattaat ttttatattt ctttcaaaaa attcttttat
    19861 taaaacatcc tcttttataa tatcttcact catcttaaaa aataccatac ttatatctgg
    19921 attaacattg tttacttcaa tgccatcaat tttatttaat tcacaagcta aatattttgc
    19981 attttcatgg tcttcattca atcttaaagt cattttttca atggcaatta taccagctgc
    20041 tgcaactata cctacttgtc tcattccccc acccataact ttttgctttc ttctagcttt
    20101 tgctataaat tctttacttc cagcaagtat agaacccatt ggtgcagcta aaccttttga
    20161 cacacagaac ataacactat cacaacactt tgctatttct ttagcttcta cacccaaagt
    20221 taatgctgcg ttaaataatc ttgctccatc taaatgtact ggtaagttat gtttctcagc
    20281 tattttttta atttctctta aattatcaag actcacaact gttccacctg aatatgcatt
    20341 ttctacacat ataagccctg tctgtggttc atgtatgtca tctcttctaa ttgccttttc
    20401 aacaagttca ggatttagag ctccactttc gtcttcatct atagttctaa gctgaactcc
    20461 agctattaca gcaggtgccc caacctcatg agtcacaatg tgataacctt taccaataat
    20521 tatttcttgc cctcttaggc aatgagtaaa tagagctaat tgattcccaa aagttccact
    20581 tggaaggaaa atagcatctt cttttccaac tttagctgct gctaattctt caagtttatt
    20641 tacagtaggg tcatctctaa agattgaatc tccaacagga gcctttgcca tagcttctct
    20701 catttcgtca gtaggcatag taacagtatc acttcttaaa tcgataaatc tcattttttc
    20761 aaccttcttt catatttata tactatagaa ccttaaaatt gattttttct gtaaagttca
    20821 tatactttca tagcttatac tctacacaat aattatacta tatttacttt atatttaatc
    20881 tactttaaat tattaatttt aaaaataaag tttcctctct aataaatata aataatcata
    20941 caatttaaat attaatctct attgtttaaa ttccccctag tcacaaagcg tatattatgt
    21001 gtataattaa tttactgact cattttggtc aaagaaaggg gtgctataaa tggcattaga
    21061 tggattagtt atacattcaa tagtcgatga attatcatca aaacttacag gtggaaaaat
    21121 agataagata catcaacctg aagatgatga ggtaattttt aatataagaa ataataaaga
    21181 aaattttaga ttggttttaa gtgcaagtgc ctcaaatcct agagtttatc ttacaagtaa
    21241 ttatcaaaaa gaaaaccctc taaaagcgcc tatgttttgt atgttactta gaaaatacat
    21301 acaaggtgga aatatagtag aaatttctca aataggtttt gaaagaataa taaaaataag
    21361 tgttgaatct ttagatgaat taaaagaaaa gacagttaaa aatattatga ttgaaattat
    21421 gggaagacat agcaacataa taataactca tggtgaagaa aataaaatta tagattctat
    21481 aaaaagagtc ccttttagca taagtagagt tcgtcaagtt ttacctggtc atgattattc
    21541 attaccacca gaacaaaata aactcaaccc tcttgatgat atatctaagg atttgtttat
    21601 taaaaaccta gaggaattgg aaggacctat ctttaagtct atatattcta aatttctagg
    21661 tataagccct attatagcta aagaaatttg ctacagagca ggtgtaaatc aaaatgctat
    21721 cataaaggat atatctgatg aacaatttga ttctttacac aaagtatttt gtaatttatt
    21781 caatgatata aattctaaca aatactctcc ttgcattatt atagataaaa aggtggataa
    21841 ggtagttgat ttcagttgta taaaccttac attatttagc gatttatcat atataaataa
    21901 ggatagtatg tctcgtattc tggaggattt ctatagaact aaagatatta aagatagaat
    21961 taatcaacgt tcatctgatt taaagaagag tatatctgtt aagcttgata gactttataa
    22021 taaacttaaa aaacaagaag aagaattatc agaatccgaa aatgcagaca tttataagat
    22081 aaaaggagaa ttgattactt catatattta tatggtagaa aaaggtatgg aaagtattga
    22141 agttgctaac ttctatgatg aaaattgtaa tgatgtaaca atagaattaa ataaaaactt
    22201 gacaccatct gaaaatgctc aaaaatactt taaaaagtat aacaaaatga aacatgctaa
    22261 agtcgagata tctcatcaaa tttccttaaa taaggaagaa atagattact tagaaaacat
    22321 aattttaagt attgaaaact gtgaaaattt agctgaatta caagatataa aagaagaact
    22381 tgctaaggtt ggatacatca agactcaaaa gaaaaacagt aaaaaggata ctatcccatc
    22441 tacaaaacct catgaatttg tttcttctga tggatttaaa atattggttg gtaaaaacaa
    22501 taagcaaaat gactatctta cactaagact tgctgataat gatgacttat ggatgcatac
    22561 aaagaatatt cctggttctc atgtaataat aaagtgtgct ggtaaggaag tccctgataa
    22621 tactgtattt gaaggagcta tgctagcagc attctttagt aagtcaaaac tttcttctca
    22681 ggtgcctgta gactatacta agagaaaaaa tgtgaaaaaa cctagtggtt ctaaaccagg
    22741 tatggttatt tatgaaacta acagtactat ttatgttact cctgaagaag aaacagtagc
    22801 caagcttaag gttaaatctg aataaattct gcactaaata caaaataaat gttagacaac
    22861 tacacattat cattctaaat aaaaatagtg gccttcttat aaagtacaat aataaggcca
    22921 ctttctaatt agcttacttt taattttcta acaaaatact tttctgtttt aataactata
    22981 cttatattcc caacaaatat tttcagtctt cttatataga tgtaattaaa aagttaacac
    23041 taaaagctat tttttaattt attgatttgt tttagtaatt cattatattc tgattcatac
    23101 aattcttttt ttagattatc tttttctata gataacatag atataacagt tgtaagtcta
    23161 ttttctaata ctagaagatt ttcttttttg atttggtttt ctctactagg agttttttta
    23221 tttctgctaa ttatatattc gtcataatta caatcaaact cccttatttt agcatctttt
    23281 atctctataa tatagttaca aatatgtgat acaaatactc tatcatgaga cactataagc
    23341 atagttttat cagtatttat cagtgccttt tccagtgctt ccatagattt tatatctaag
    23401 taatttgttg gttcatcaaa tactaaaaaa ttattatctt ccaatattat tttacatagt
    23461 gctattttta ccttttctcc accactaagt acttttactt ttttgtagac atcatcacct
    23521 ttaaacccaa ataggcttaa gtttatcctt ataaaagatt catcaaatga actattaact
    23581 ttagtattgt atagaacact cttttcctca tctaataaac tttgattttg gtcaaaataa
    23641 cctactttta ccttgttatt tatttttata ttgtcatttt tatcagccaa tatttctttt
    23701 atcagagtac tttttccaca cccattatca cctaacaatg ctatcttttt acctcttttt
    23761 atcttaaagg aaacattatc taacaggagc ttattttcta actttagagt catatctttt
    23821 acctctacta gatttttgct aattatctcc ataccatctt gcatcttaat gttcatttct
    23881 ttagaaactt taggtttatt ctttacctca agtttatcaa ttctgctttt tatagccttc
    23941 acatttgagt ccaacttttt cttattagtc tgaccaccca ttttgtgcaa cctagcttct
    24001 gaattaccca ttctttttgg tgtttttctt atgccatcac ttaaagcttt tttatataaa
    24061 agagcttttt caagcctttt tttctcttta acatattctt gatactcaaa atcagctctt
    24121 tttacttctt catctttttg cattaaataa tcagtgtaat tgcctttgta agcttttagt
    24181 tttccatctt ctagttctaa tatagttgta cataactcat ccagaaaacg tctatcatga
    24241 gatattaata ataatgctcc ctcatgcctt ttaaacatat cttccaaaac cccaatgctt
    24301 tttttatcta agtttgaagt tggctcatca gctattatga tatttttctt attactcagc
    24361 gcatctgcta tttttaactt aaccttttcc cctcctgata agtgttcttc aaatttatct
    24421 ggagcattta aaagactctt ctccttacta tgactacatg tttcaatatt attttcactc
    24481 tgacttatat aagaatagct ttctgtaagg taagtatatc cttcatcaat ttctatttct
    24541 cccaatattg cttttaataa tgttgttttt ccttgaccat ttgaaccaac tagacctatt
    24601 ttgtcatttt ctaatatttc aagtttatct atatccaaaa ttaatttatc tgcataatat
    24661 ttctttaaat tctctacttt tactaacaac ataaaaaatc cctccttaac acacttaaat
    24721 ataaggagag attctataaa taggcataac aaataaacgt atagactata atctactctc
    24781 cttaatttaa gcattgcaaa taaagccacc aaaataggct tttcaaaaat tacaatactt
    24841 taaattataa aaaatagatt atattctcat tgtcctagtt accttgccct ttctttcatt
    24901 tatttttaat cattatatca acattaatta caaatgtcta tagaaaatta actaatttta
    24961 gttattcaat atacaactta ttctttaaat ttattcttct tcaactttaa agtcctgatt
    25021 atttaaaatt ctgtttaata caattccaac aattgcagct aaactaagac cagttatctt
    25081 tactgtactt gttataggga ttccaacaga aataccttta ttagataaat atgttgttcc
    25141 aagacctatt aataatataa ctgctatgat taatatattt attttacttt ctacacaaga
    25201 actgtccctt atagttttta atcctacata agttatcatc gaaaatagca ttatactaat
    25261 tccacccata actgaacctg gtatactttg aagaaatcca ccaaacttgc ctacacatgc
    25321 aagcaatata gcaaatattg ctgtacgtct aagtattgaa gggtcatagt ttttagttat
    25381 agcaagtact gctgtatttt ctccataagt tgtattggct ggtcctccta aacaccctgc
    25441 aactatagtc gcaaatccat ccccaagtaa tgttctattt aatccgggat tttctataaa
    25501 gtttttacct actacagcac cattagtagt catatctcct atatgttcca taaatacagc
    25561 taatacaact ggagatataa tcacaattgc tcctaaactg aacttaggaa ctgtaaagtt
    25621 aggtattgca aataaacttg cttctgtaat agtagttata tctactaatc ttaatatcaa
    25681 acagattata tacccagaaa aaactgctat taatattcct aattgtttta taaatcctct
    25741 accaaactta ttggttaaaa ttgctattgc taaagttata aatgctatta caaaattggc
    25801 tgaagccata ctaaaagctg ttggcaataa atttaatcct ataactacta tcatagctcc
    25861 tgtaacttgt gcaggaaaat ataatttaat tttatttaca ccaactattt ttactataat
    25921 cgacattata atataaatta atcctgctac tattatacca ccttgagcat atgctaaatc
    25981 tccaccatac gcctctttag ctgctagtat aactggtata aacgcaaaac ttgaacctaa
    26041 aaaggcaggt acttttcctt ctgtacaaaa atgaaatatc aatgtaccaa caccagcaca
    26101 gaaaattgca actgacggat taaaacctgt caaaatggga actaatactg tcgctccaaa
    26161 catggctaat agatgttgta aagacattat cgtttttttc ataaaaacct ccaaaattat
    26221 tatatataaa taaatcctct gtttaattaa tatcttttaa ttaattatca ttccctagat
    26281 tctatttttt aacctctata tacttattat ataatttatc attattttac attttacgac
    26341 atcaaaaact caaataaagg agaataaaaa ctacattaag actcacatcc ataaaattat
    26401 aatatttatt ttgtgcaatc tatgtaagct ttatcctcct ccctgactat tcaatgctaa
    26461 gcttttatat aatacttaaa aataattatt ctttgattgt aactgaatct tctccatcaa
    26521 tttctaataa actgacagat ataatttcat gtctagaagt aggtacattt tttcctacat
    26581 aatctgctct tataggcaac tctctatgcc ctctgtccac tagcactgct aattgtattg
    26641 atttaggtct tcctatatct ataatagcat ctagtgaagc tctcacagtt cttccagtgt
    26701 ataaaacatc atcaactaaa actactgtct tatcatttac attaaaatct aaataagttc
    26761 ctttaactac aggttcaaca tgaatttttt ccaaatcatc tctatacaaa gttatatcaa
    26821 tatctcctgt atctactttt gttccttcta tttgttctat tttcttagaa attctatttg
    26881 caattggcac acctctagtc tttattccaa ctaaaactag attttctaca cctttatttc
    26941 tttcaattat ttcatgactt attctagtaa ttgctcttgc tattgccttt tcatccatta
    27001 attgagcttt ttctaccata tcataattat tgtcaaagat ataatatatc tatttgacaa
    27061 atctactcct ttcttttaat tttttataaa tttattttta tttaaaattt caatttaaac
    27121 aacaaaaaaa cttctcatca caagacaaga agctcttata taaaaaatat acagtgcaat
    27181 ttagcaattg tcttacgata tctctgtatc gtttaaagat aattttttaa tctatcaaat
    27241 caaattatat atttatattt caaatttttc aagctttttt aaacaaaata ctttaatata
    27301 agatatttta tttaaatttc actaaattta tttacttata taaaaacaaa aaatgattta
    27361 taagtattat acaaatggtt attttatctt tttaataact tccttaaaat actcaggtaa
    27421 ttctgaatta aattcgatat attccttagt agtaggatgt ataaatccca acttcttagc
    27481 gtgcaaagtt tgtcctttta atttaaattt agtttctttt ggaccatata cataatcacc
    27541 taaaagtggg tgatttatag acaaagcatg aactcttatt tgatgagttc taccagtttc
    27601 aagcctagct ctcatatgtg taaacttatc aaatctttct acaacttcaa agtgagtgat
    27661 tgcatttttt ccatctttta ctacagccat ttttaatcta tccttaggat ttctccctat
    27721 aggtttatca acagttattt tatcttcttt aaccacacca tagcatataa attcatactc
    27781 cctagttata gtatgttcct ttaactgttc tgctagaaaa ttatgtgcat aattgttctt
    27841 agctatcata agaagaccag aagtatcttt gtctattcta tgaactatac caggtctaat
    27901 aactccattt attgatgaca acttatcttt acaatgatat aaaatcccgt ttactaacgt
    27961 attttcatag tttccaggag caggatggac aaccatatcc tgaggtttat ttattattaa
    28021 gacatcatca tcttcatata caatatctat tggaatatct tgaggtaaaa cttctaatac
    28081 tttaggttct ggtatctcta taacaatatt atcttcctct ttaaccagat atctagcttt
    28141 ttctacttta ttattaacct ttacttttcc atcttttata attttttgta tataacttct
    28201 tgacatatca cctaattgtt ctgctagata aatatcaagt ctaacttctt cttcctcttc
    28261 aattactaaa aactctttta cttcatccat tatatcacct acttttactt tcaaaaaata
    28321 aaacatatat acataaaaac acagttccta caactacaaa tacatcagct atattgaata
    28381 catattccca tataattcta aagtcgaagt aatctactac aaaacctaat cgtactctat
    28441 caattagatt tcccaatgca ccagatataa ttaatataat tcccaacctt ccaaatatat
    28501 gtactttcct tgtattaaga tagtatagtc caaatactgt tgcaagtaat gcaacaatta
    28561 taaatatcca ttgattattt tgtaataatc caaatgctgc acctctattt tcgacataag
    28621 ttaaatgaaa tacattattt attattggta ttgttgatac atccaccaaa ttattcaata
    28681 cccatatttt agacagttgg tctaaaccta tgagtagaat tattattaat atatatagca
    28741 atgatttttc cccctataaa ttatttaaaa accaatttta tttgaagcac actattatta
    28801 ttatacaaaa aaaatgctct aaagagcaac tttattaaaa ttgtattttc ttagtaaagc
    28861 tagaacaaaa tttaaaatag tactcctttt tttatattgt agatttctac atatttaaaa
    28921 tcatatcatt atgtataaaa aatttaaaaa taccatacta atcaatactt tttgtgtatt
    28981 ttatagatta aagattaatg atgtctgtaa tttaaactta caagcaccac taatcttcaa
    29041 acaaatattt ttacttttgc acttgtttat ttttatctaa atgttgtata agttcagata
    29101 ctgttacgaa tttatatcct ctctctttta atttaggaat tactacttct aaagcttgta
    29161 tagtttgtga tttatcattt cttttagtgt tataatcatg taaaagtatt atattaccat
    29221 tttggacctt tgtaaggata gtatttataa ttgcatctac tccagggtta gaccaatctc
    29281 tagggtctaa gtttgaccaa agaattatat tcatgccttt agaaactata atatcacaga
    29341 cacttttact catggctcta tatggaggtc taaatatctt tggttctact cctattacac
    29401 tttttataat attttgcgta tctgttattt ctttttcaac actactataa ctattttttg
    29461 caacatttat atgtgtaaat gtatgattcc ctatttcatg cccctcatca tattgtcttt
    29521 ttaataattc tttgttatat tctacttttt ctccaactac aaaaaaagtt gcttttacat
    29581 catttttctt taatatatca agtacttgtg gtgtaaaatc ctcatctgga ccatcatcaa
    29641 aagtcaatgc taaaattttt tcatcctcat ttcctttttt tattattaca tcttcataat
    29701 cgtcttttat attgtcattt aaactatatg cttcttttga actatcttga ttatgtgtat
    29761 tatgactata tgtatataca cctactacag ataataaaca tatacatata ccccatatta
    29821 ttttcttcat gtcattacct cttttctaat tcattctagc aatatatttt ataatgtcag
    29881 ttttttaatc tctcaatatt ccatttttat ttaaatcagt taaatttgtt aggtcttctg
    29941 aataaaagtt agaatcttct acatcagggt tttgcattgc atcacctaat aaattatttt
    30001 ctttctttgc acaatcatta cataaacttg tatctggcaa tatatccaat ctttctaaat
    30061 ctatttgatt atgacataaa tcacaaatcc catatgttcc attctctatt ttagataatg
    30121 ctaagtctat ttgatacaat cttccctctt catgatttat tagactgttt tgcatatttt
    30181 gcatatataa atctgttccc atatctccta tatgattatc ataactagat aattctcctg
    30241 atgaatactt ttcacttgta tgtttagttg tatctccaaa taaagtatta tctttcatat
    30301 cctctactaa attagttaaa ttttctcttt ctttcaataa tttatcttta tattttttag
    30361 tatccatttt taacacctct aattttaata tttatatcat aaaaatagta tgtggaaaag
    30421 tgaattaaac atacaataaa aataagattt gattctaaaa atggaatgtc tcaaaatgaa
    30481 aattttagtt catttaaccc tcttttttat ctgaaatcaa atatattttt atcctttcaa
    30541 caataaaaaa gagacttatc tctattttga gatagtctct tctttgaaca taatttaaat
    30601 ataatttttt aatttttata gttattattt tactaacttg ccaatttatg attattttgt
    30661 tctttaatat gttttgcttt tttagagaat aaaagagcaa gaattattgc tacaataaca
    30721 cctattccat tagatatatt aactggtagt ctaaatcctt cttttgcttg cattatataa
    30781 ctaaatgtta ctacagtcat aaaaagtgct ggtaatgtag ttatataatg gtttttattt
    30841 gctttgacta aatatgcaga accagtccac aacattatca ttgcaagtgt ttgatttgcc
    30901 caagagaaat atctccaaat tatattaaaa tctataaatg taagagcaac accaactgcg
    30961 aataatggta aagctattaa aaatctattt ttgactgcat cttgattata attcattgca
    31021 tctgctattg tcagcctagc acttctaaat gctgtatctc cagaagttat aggacatgcc
    31081 acaactccaa gtatagctaa agctcctcca ataggaccca ttaatccaac agatactgta
    31141 tttactactg ttgctgctcc accatcatta aatatcacat taagttgagg tatgccatgg
    31201 aaatatgaca tggctgctgc tgcccaaact aaagctatta taccttctgc aaccattgac
    31261 ccataaaata ctggtcttgc ctcactctct ttctcaacac atctcgccat aagtggtgat
    31321 tgagttgcat gaaaacctga tattgctcca catgctattg ttataaataa gtatgggaat
    31381 aaaggtgttc catttggatt catattttgt aaatttatat ttggtatgtt ataccccttt
    31441 attattaatc ctccagctac acctactgcc ataattaata atgctgctcc aaataaagga
    31501 tatattttac caatcaattt atctattggt aaaacagtag ccataatata ataaagtatt
    31561 atcactccaa cccatatttg tgcgtttaca cctgtcaatg tctttaataa tcctgctgga
    31621 cctgttacaa atacaactcc aaccaatact aaaagaataa cactaaatat tctcattgct
    31681 atttttgcac catttcctag ataaaggcct accaactctg atgcagatgt acctttgttt
    31741 ttcattgata gatatcctga agcaaaatcg tgtactccac cagcaaagat tgttccaaac
    31801 acaatccata aaaatgctga tggtccaaat aatgcccctt gtatagctcc aaatatcgga
    31861 cctaaccctg ctatatttag aaactgaatt aaaaagattc tcttccattt cattggcaca
    31921 taatctactc catccctaca agctatagct ggagtttgat ttttgtcatt ggttccaaaa
    31981 accttttcta caaaagtacc atagacaaaa taacctacta taagtactac tattgaacct
    32041 aaaaagctta ccataaattc atccccttag tttttatata attgctttat aaatttttat
    32101 gagtttaaga aaactatttc cagttcaaat agtaatactt ttttatgcta atataaatat
    32161 taattacatt aagtgcatat ttaagtacat gaaatgactt tatatatgca ttaacagcct
    32221 aaattctttt actttgcttc tacttacagt tacttcataa tcactatttt ttaattttaa
    32281 tatgtatgta ttattaaacc atggtataat ttcttttact ttggttaagt ttacgatata
    32341 agacctatgt gttctaaaaa atgttttatc atttataaga ttttcgactt cttatatgcc
    32401 ttcttttaat ataaactttt ctttctcagt atatataaat gtctgccttt cattagcttc
    32461 acagtaatat atatcatcaa tatctattac aactaattta tcacctttcc aaaggctaat
    32521 tttatgtgtt atttcttcta tctcctgatt tactgcttcc ttcttatatt tgtataaatt
    32581 actatttaca ttagatagtt caatatcact catctcactt ttttctaatt tattcagcat
    32641 agaaataatt ctctcttcag aatatggttt caatatataa tcaaatacat ccaaagaaaa
    32701 agcatctact gcataacttt catatgctgt tataaaaaca attttaggtc ttgatttaaa
    32761 ctgatttaat gtttttgcaa gtagcattcc atcaagatga ggtatattta tatctaaaaa
    32821 aattacatct attttatttt cctgaataaa gtctaacacc tctataccat tggtaaattc
    32881 acttactacc tctattccac ttttattttc aataaaatat ctcaattcct ttcttgctgg
    32941 aaattcatct tccactatta tagctctcat acttctactc ctttacataa aatactatca
    33001 aagtcccatt atctattctt cttatattaa gccctcttcc atacatcagt ttaagcctta
    33061 aatgtacatt ataaagccca atcttatttt ctggcatatt atcttgatat acattattta
    33121 taatttcctc acttatacct ataccattat cctctattga tattctcaca gtattttcta
    33181 atgaatacgg taactttttt atggatattt tcactacacc agctctacca ctttctaaaa
    33241 taccatgtat tattgcattt tccactaatg gttgtataat caaacttgga atctttatat
    33301 ttacatcttc tatatcataa gatacagtta gtaattctcc aaacctagct ttttctatct
    33361 ctacaaaaga tttaacttgt tcaatctctt tatttatatc aattaagtta tcactatatt
    33421 caagattata tcttagataa gttgataaat ttattattaa ctctctagcc ttatctggac
    33481 taaatcttat aaatgaagct attgtgttta gggaattaaa caaaaaatgt ggattaattt
    33541 gtctttgaag tgcttttatt tctgctttat ttctcgcttc tatatctttt ttatctttct
    33601 caatcccctc tactatagat ataacaaatc ctattccaat ctgcccaact attaaaggta
    33661 aatatattcc accgattatt tgaattgcta aagaatgtgg atatgatatt aagtatataa
    33721 gtaatatagt aaaactttca gaaatcatgc ctaccaatat tccatacatt actctatgtt
    33781 gttttggtat cctcttatat agaaatcctg ataatacacc tgctagtata cttgataaaa
    33841 gacatggaac agatgttatc cccccaatat ccataaaata tctatgaatc cctgaaaaaa
    33901 ctcctgctgt aatacctacc attggaccaa ataaaatgcc acctgatact atagatatta
    33961 ttctagtgtt tactattgac cccatataat ttataccact ataagttcca aatatggcta
    34021 aaaaagtaaa aactaatgct atacagacca agtcattaaa actatattct tccttttgaa
    34081 atatctgctt aaatattttt aactttgtta ttagaagaaa caatactaca ataaggcttg
    34141 tcttttctat taatgcgatt aaaattgatg ttttcataat ccccctttaa aaaataaaac
    34201 attacttaat ttaagtttat tattcttata ataaattaga tacataaaaa taaattccat
    34261 aattattgta tcatatcacc tatatataaa cataaattca tttaattata taaatttaaa
    34321 aaatattttt ttgatatatt attgacaatt ttcattataa gagttaaaat taactcataa
    34381 attacatatt gggtataaaa tacaatgtat gttagaagtt gtttcagaag gctatggttt
    34441 tctgattttt ttatgctcag tagtgatatg caaaaaagac aaagttgaca tcagttaact
    34501 tttaccttta ttctactttc cccaaagtaa gaataatcta acccctttga gatgagcaaa
    34561 agctcatctt tttttattat caaaagatgc tgtctcaaaa cagagataat cctctttttc
    34621 attgttgaaa tgattaaaat atattttatt tcatacaaaa aagagtgcct catgaacaaa
    34681 agttcacttt gagactctct ctttcatatc atataccttt ttaataactt taaaatttat
    34741 ttataaagta aagatagcta ataattagta tcttctctct ataaatccaa cttttttata
    34801 aacttttcta agagtttttc tagcttgttt ttcggctttt tctgctccca tactatatat
    34861 tttttctaaa taatctttat tattaagaag gtcaacatat ttttctctta taggtcttaa
    34921 agcttctgat actacttcag ccacatcttc tttaaatatg ccataaccct ttccttcata
    34981 catgtttaca atctcttcta cactcttttt acttaaatta gaatatatat caattagatt
    35041 tttaatacct ggttgttcat cattgtattt tacaacacct aaagaatcag taacacttct
    35101 ttttatcttt ctctttatag aatctgaatc atctgctaat agtataaatg cattttcatt
    35161 tgaatcggat ttactcattt ttttagttgg ctcttgcaaa ctcatcactc ttgctccacc
    35221 ttttgggtag tatccttctg gaactacaaa agtaggtgaa aatctattat taaacctatt
    35281 tgctaaatca cgagctaatt ctaaatgttg tttttggtca tctccaactg gaactaggtc
    35341 agtttgatac aacaatatgt cagcagccat aagaactgga tatgtgaata aacctgcatt
    35401 tagatttgct tcactctttt gtgatttatc tttgaattga gtcattctac ttaattcacc
    35461 catataagtc atagtattca atacccacat aagttcaaca tgctctttga catgtgattg
    35521 tataaatata gtattttttt ctgggtctaa tccacaagct atatattgag caagtaattc
    35581 tatagtattg gctcttaaaa ctttagggtc ttgaggtact gttattgcat gcaaatcaac
    35641 tatactataa taacaatcat aattgtcttg aagttcagtc cagtttttta tagctcctaa
    35701 ataatttcct aaagtcattt tgcctgatgg ctgtgcacca cttaatataa cttttttttc
    35761 actcattttt ttgtacctcc ttatatattt atattgattt taacatattt aaaactatgt
    35821 ctttagagtt attggcagca tcatgtacaa atacatcata agtaacatca gcacttccat
    35881 ctgccttatc agacattgct cttattatta caaatggagt attatttaaa tagcatacat
    35941 gagctatagc tccaccttcc atttctccac aatatccacc aaaatcattt actaattctt
    36001 cttttaattc tttagaattt ataaatttat ctcctgtaac tactcttcct tttaatactt
    36061 tatgagtctt tacttcttcc acagaagatt tgtaagcagc atctataagt ctttcatctg
    36121 ctttaaatac agaagtcttc attcttggta taactccctt agggtctcca aatgctgtag
    36181 tgtctacatc atactgtata gcatcagttg atattactat atcattaaca tcaagttttt
    36241 cgtttaaagc tcctgcaaca cctgtattaa caatagcatc aaccttaaat tcgcttatta
    36301 gtatctgggc acaaagagca gagttaacct tacctatgcc acactttact aacactacat
    36361 tcttaccttc caaaattccc ttataaaatt ctaagctagc tttttttata gtctctctaa
    36421 tatccattaa atcaactaaa atactaactt cttcatccat tgcacctata attcctatta
    36481 cgttcatttt tcctcctaaa ttttctatat taaaaaatcc gtcctaaatc aataggacgg
    36541 atatattttc cgtggtacca cctaaattta tatacactca aaattgaata tatatatctt
    36601 aatatatgct ataacgtgca tacacgatat caaatactct gtaatcttaa attacatttc
    36661 attttactcc tcaaagaccc attcaataaa tactttttat taagttctca gcatccttaa
    36721 ttctctgtgc aaaaatatat ttatttacta tttcttatct caggatttaa tttattaatt
    36781 tctttatttt ataatattcc ttacactata aattgtcaac tatatattat aatatccaaa
    36841 agaaattttt aaaatacatt ttatttagct gttttctttt catatctatt ccataaccat
    36901 agaccagata atataactag aagacctcca ccaatcatct ctatctcata tataacattt
    36961 tcagcaaatg taggcataac tggtgctgca gataataata tacccactac agttacaact
    37021 aaaaccattt ttgctaaacc taggcaagta cttgttgatt ttgccatagt ataaggtcta
    37081 atttcatctg gtctctcttt tcttagttta atataagaag catataacaa tacatatggg
    37141 aataatgcag ttaatgctgt catagttaca agaacattgt atatagcatc aacagaaggc
    37201 attaatgtag tcaccaatag tattatagta actattattg cttgaagtat aactgcttta
    37261 gaaggtatct tgtgttcatt tacctctact aaactatctg gaaatattcc ttttttaaca
    37321 ctaccaaata acatttttat tggtgatgct atgtaaagaa ctattgctcc taatactgaa
    37381 aaagctatac caaaagctat taattgaacc aaccaagaac caattcctaa agacgcacaa
    37441 acagcagaaa gtgcatctaa tacaccttta gaagcagtaa tttggtctgg tggtattatc
    37501 attgttattg caattgaacc taatacatat aatgaagcta ctattccagc tgatattaat
    37561 attgccttag ggaagttctt ttcaggctta tctatttctg ttatgaagtt agcagcagtc
    37621 tctgctcctg ctaaaccaaa cattatagct gatatagcaa caaatgcatc catattaagt
    37681 tttggagtca ttgaagctat tgtgtatgta gaagctatat catgtttttt caacacaaat
    37741 actgctacaa atgaaaatat tataagtata gcacttggta ttgttgaacc taatgcacct
    37801 gtattagtaa atatttttgt aaaacttatt cctttagttg ctataagaga taatgcccag
    37861 aatattatta aagataatat aagtacaaac atcttattat cagcaagggc tggatttcct
    37921 attgtataag aaacatttac tgctaagaaa gttaaaaatg aagaatacca aaatatttta
    37981 gctgtccagt ttaaccaaga aactaaaaat ccatactttt ctccaaaggc ttccttaacc
    38041 caatcgtaaa gacctccatc acctttttga tatgtagaag ctaattcagc acaaattaaa
    38101 gctcctggta caaagtatat aaatgagaat aataaccaca taggtattgc acctaatcct
    38161 aaaccaaagc ttgatgctgt agatttagct atccatctta taccatataa agctgataca
    38221 ttcataaata ccaaactcca taggcctatt tttttctttt ccatcctaat ttaatttccc
    38281 ctctctatta attattttaa atttaatttc aaaattaata aaatagattc attattatta
    38341 aactgatatt tttcaaaata tttgcatatt caaaaacagt tttaataata aaccttaaat
    38401 actttgaaat caaatcttat taaaaatgat aaatttaaaa gttttaccac tttaattcta
    38461 atgatact
//
LOCUS       DAEPUT010000038        37259 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.039, whole genome shotgun sequence.
ACCESSION   DAEPUT010000038 DAEPUT010000000
VERSION     DAEPUT010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37259
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.039"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(411..551)
                     /locus_tag="KRL22_002011"
     CDS             complement(411..551)
                     /locus_tag="KRL22_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272501.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(811..1971)
                     /locus_tag="KRL22_002012"
     CDS             complement(811..1971)
                     /locus_tag="KRL22_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HBH1272502.1"
                     /translation="MKLSKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            complement(2142..2345)
                     /locus_tag="KRL22_002013"
     CDS             complement(2142..2345)
                     /locus_tag="KRL22_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HBH1272503.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            complement(2432..3466)
                     /locus_tag="KRL22_002014"
     CDS             complement(2432..3466)
                     /locus_tag="KRL22_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HBH1272504.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            complement(3988..5349)
                     /gene="rlmD"
                     /locus_tag="KRL22_002015"
     CDS             complement(3988..5349)
                     /gene="rlmD"
                     /locus_tag="KRL22_002015"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH1272505.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMNEFKDMLLGIDLKSELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            complement(5376..6098)
                     /locus_tag="KRL22_002016"
     CDS             complement(5376..6098)
                     /locus_tag="KRL22_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBH1272506.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYIEYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(6098..6427)
                     /locus_tag="KRL22_002017"
     CDS             complement(6098..6427)
                     /locus_tag="KRL22_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HBH1272507.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIREGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            6757..7683
                     /gene="fba"
                     /locus_tag="KRL22_002018"
     CDS             6757..7683
                     /gene="fba"
                     /locus_tag="KRL22_002018"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HBH1272508.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVEGKIDDVLGSANSIN"
     gene            complement(7951..9582)
                     /locus_tag="KRL22_002019"
     CDS             complement(7951..9582)
                     /locus_tag="KRL22_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1272509.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(10065..11102)
                     /locus_tag="KRL22_002020"
     CDS             complement(10065..11102)
                     /locus_tag="KRL22_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH1272510.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(11121..11906)
                     /locus_tag="KRL22_002021"
     CDS             complement(11121..11906)
                     /locus_tag="KRL22_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1272511.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(11939..13072)
                     /locus_tag="KRL22_002022"
     CDS             complement(11939..13072)
                     /locus_tag="KRL22_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH1272512.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(13120..14247)
                     /gene="hadC"
                     /locus_tag="KRL22_002023"
     CDS             complement(13120..14247)
                     /gene="hadC"
                     /locus_tag="KRL22_002023"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HBH1272513.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(14247..15473)
                     /gene="hadB"
                     /locus_tag="KRL22_002024"
     CDS             complement(14247..15473)
                     /gene="hadB"
                     /locus_tag="KRL22_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HBH1272514.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(15488..16288)
                     /gene="hadI"
                     /locus_tag="KRL22_002025"
     CDS             complement(15488..16288)
                     /gene="hadI"
                     /locus_tag="KRL22_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HBH1272515.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(16327..17526)
                     /gene="hadA"
                     /locus_tag="KRL22_002026"
     CDS             complement(16327..17526)
                     /gene="hadA"
                     /locus_tag="KRL22_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HBH1272516.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            18203..19201
                     /locus_tag="KRL22_002027"
     CDS             18203..19201
                     /locus_tag="KRL22_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HBH1272517.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            19563..20090
                     /locus_tag="KRL22_002028"
     CDS             19563..20090
                     /locus_tag="KRL22_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HBH1272518.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLATTILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMSLDKLDFKKRYFN"
     gene            20117..20713
                     /locus_tag="KRL22_002029"
     CDS             20117..20713
                     /locus_tag="KRL22_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HBH1272519.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKDVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(20778..22360)
                     /gene="asnB"
                     /locus_tag="KRL22_002030"
                     /pseudo
     CDS             complement(20778..22360)
                     /gene="asnB"
                     /locus_tag="KRL22_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
     gene            complement(22425..22562)
                     /locus_tag="KRL22_002031"
     CDS             complement(22425..22562)
                     /locus_tag="KRL22_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272520.1"
                     /translation="MKNKKFNVITLIILDNHIYAINKEQISTNSKRIYFEKSRFFSDY
                     K"
     gene            complement(22926..23762)
                     /locus_tag="KRL22_002032"
     CDS             complement(22926..23762)
                     /locus_tag="KRL22_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1272521.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(23786..25252)
                     /locus_tag="KRL22_002033"
     CDS             complement(23786..25252)
                     /locus_tag="KRL22_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH1272522.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQRKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIESNSIDFK"
     gene            complement(25255..27117)
                     /locus_tag="KRL22_002034"
     CDS             complement(25255..27117)
                     /locus_tag="KRL22_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1272523.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTKFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(27364..28227)
                     /locus_tag="KRL22_002035"
     CDS             complement(27364..28227)
                     /locus_tag="KRL22_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH1272524.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFTNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(28282..29214)
                     /locus_tag="KRL22_002036"
     CDS             complement(28282..29214)
                     /locus_tag="KRL22_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HBH1272525.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(29300..29851)
                     /locus_tag="KRL22_002037"
     CDS             complement(29300..29851)
                     /locus_tag="KRL22_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1272526.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(30080..30571)
                     /locus_tag="KRL22_002038"
     CDS             complement(30080..30571)
                     /locus_tag="KRL22_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272527.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(30599..31159)
                     /locus_tag="KRL22_002039"
     CDS             complement(30599..31159)
                     /locus_tag="KRL22_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH1272528.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(31311..32468)
                     /locus_tag="KRL22_002040"
     CDS             complement(31311..32468)
                     /locus_tag="KRL22_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH1272529.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(32505..33446)
                     /locus_tag="KRL22_002041"
     CDS             complement(32505..33446)
                     /locus_tag="KRL22_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272530.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYKNMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(33533..34225)
                     /locus_tag="KRL22_002042"
     CDS             complement(33533..34225)
                     /locus_tag="KRL22_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1272531.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRFRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(34334..35146)
                     /locus_tag="KRL22_002043"
     CDS             complement(34334..35146)
                     /locus_tag="KRL22_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBH1272532.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(35197..36108)
                     /locus_tag="KRL22_002044"
     CDS             complement(35197..36108)
                     /locus_tag="KRL22_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1272533.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(36167..36898)
                     /locus_tag="KRL22_002045"
     CDS             complement(36167..36898)
                     /locus_tag="KRL22_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBH1272534.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            36987..37238
                     /locus_tag="KRL22_002046"
     CDS             36987..37238
                     /locus_tag="KRL22_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272535.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
BASE COUNT        11909 a         6666 c         4096 g        14588 t
ORIGIN      
        1 gtatacatta taaattatat taaattttta atttaagtaa tagtatatgt aatctttagt
       61 catcttctta ccagtttttt atccactttt ctaatgaagt tattttttca tatgttaatt
      121 cctcttgaaa taatgatact aaaagacttt ttataaaatt ataacttaaa agtttatgta
      181 tttttttgat atgaatttat agtacttatc ttctttaatt gagattgtgt atatttaact
      241 taaatattac atcaataatt ccatgcaatc aaatcaatta tttacatatt tttttagaac
      301 aataataagt atatattcac aaaattttgt gttaatattt ttagtttgtg atataataaa
      361 agcaaggaaa catattttac ttaactttga gtgatgtttc cttcaacaaa ttattttgaa
      421 gatttacttt tctggaactt tatattaagt tcccagccac tcttagttgg tcgctcagag
      481 tggctcttta atttatcgta aatgtaactg gctataacac cagttataat actcatcatt
      541 agattttcca tagttttcac ctcctctcat aagaaagtga agaaacttcc atggaaacac
      601 cactcatagc tttttcaaat atttattcct tgccatatta attatatcat aaatattgga
      661 aacataaaat tttaatactt atcgtcttta ttattatttt ttataattaa taattttctt
      721 tttaataata cataatataa atttatattt cttcaataaa aaagacaatc ttaattaatt
      781 gtctttttta atatatattt ggctaataca ttattttaca caaacattac aagggtctat
      841 tttaccttgt gacttagctt gttttaatgt tactttattt attgttttac ttctttttag
      901 tgtagaacaa ttttttgtta gatgatatga ttttccatta ggagttacat atactgtact
      961 tttatcagtt aatccaggat tattagagct aggctcatta cttggtttgt tcgtattatt
     1021 tgaattagta tcttttacaa tacctgtatt tgaatcccca acattattag ttatatttaa
     1081 acattgtttt ataacaacat catcaatatt tccaatagca gttattttac ttgcattttt
     1141 taatatactc ttattacttc catttccaac taacactata ggtgtttttt gtgcaattgt
     1201 agaaccaact aaagaataaa ctaaatcagt cccacttgct atgtaaaatt cttttgagcc
     1261 attataaaat ttatttatta tttgtttatt tgtatcgtat ctatctactc cacctattct
     1321 tgttgcttta gtttcattta ttaacttatc actcatactg acttttccac caattgcata
     1381 agtttctaat ccatctgtag caaaacttgt agtatttcca tcagttaata ctattggaga
     1441 tttatctcta actgctatag aagcaacact catagcatct ggttcgcctt taaaagcatt
     1501 agttaatatt acttttttaa ccgtacttac tcttcctatt tcttttgcaa ctttatgact
     1561 tgtatctatt ctatcagttc cacttattct atttatgctt atttttttat cacttaatat
     1621 tttctgaact gatgctccta tcgaattttt tcctccaatt agatatactt cttttacctt
     1681 ttctaatctt tttaatgttt ctgaagggat tgtatctttc ttagttaaca atattggggc
     1741 atttttagct cctgacaatc cacttgctga caatccatca gataatccat tttcagaatt
     1801 aataagtatt gcaatatcat aattttgttt atctgctatt aaacctgctg tttcatactt
     1861 atttgtacct tttattgaat taatagaact aagagcgttt gatgttggac aactagcaat
     1921 caataatgaa acagacatcc ctattgccaa tagtgttttg cttaatttca taatgaaatc
     1981 ctcctataaa ttttataata ttacttaaat attataattc tacataaaag aatattttcc
     2041 tttatgaaat tagtttatat ttcaaaattt tgtcactttt taaatctata tactaaaaaa
     2101 tagactattt gtaacagtct atttcttagt atatcaaata tttatttagg tttacgtttc
     2161 tttgtactag tttttgtata tgatattcca gttccaggta tactcaatgt agctgatttt
     2221 cttccttttg aattaactga cactctagca cctttaacac cagcacttat acctacactc
     2281 ttcttaccta aatttaattt gagtcctcct cctagattta tgcttttcct aaagttaaat
     2341 cccatagata taaccttccc ttctatattt taaatattta tacttaaaat tatatttgtt
     2401 atacacttgt catcattggt atatctagca tctatatctt tttacgtttt ttcttcttat
     2461 atactactcc agcaactaca gctgctgttc cagctccaac cccataagta gcatttctac
     2521 ttttctcttc ctctcttttt tctaaacctt catcatatac accttttaac ttagtttcaa
     2581 tagacttcat ttcatctggt atactaaaat cttcttcatt gtaaccttga ttatatacac
     2641 tttcttttgc tttaggtaac ttaaccttac cattatcata tccttcttta aaccaattag
     2701 catatttaac attacctata gttgatgtgt caaatctttc tcctttgata gcactctcaa
     2761 atccttgagt agtgtaatca ttttttaatt gttcttgtat ttcgtcataa gcattattat
     2821 aagcatctat aaattcagaa tctatgtttt cttcaaatgt cattttttct ttatctttat
     2881 tgctatcctc tatcccttta gctttatatt cttctatctt tttagtctta tattcattgt
     2941 atccagttga atatccggta tcataagcat tttttaaaac ttctttttca tatgtattat
     3001 tagatttagc acctgtaagc cctaaattat atccagtctc tttagccacc ttttcttcct
     3061 cttctaattt agccttacct ttttcatatc cttctgagta ctttgattca tatgtatcac
     3121 tataatctcc actataattt gatgaactat aatttccttt atacccatct tcataccctt
     3181 gattatatcc tttttctcca acagacctct tttgcttttc ttcattatta accgaagttg
     3241 ttgttccaga actgcttcct cctccagtat aaggacaacc accattatta tgtaaatgag
     3301 ctggataacc accacaatga tagtgataac ttcctaatcc agatttattt ttattatcac
     3361 gatgacctcc tgatgaatca gttcttcctg aatgagcata cgaaaagctc cctacactaa
     3421 tcatagttat actcattgca acagctatta actttttctt aaacataatc tatttccccc
     3481 taaaatattc tatgatttta ttatatcagt caatatatta tgtttaaacc gttaaaattc
     3541 gacaatgtaa atatttgatg aattgtattt gtaaataaat cttttagcat atcttgaata
     3601 tctgtagttg ttttgacatc atattcttca ataagttttt taatatttcg tttttgttaa
     3661 acataaaaag catgcacttt cctttgtata gtgatatttg atattttaat tatcactact
     3721 ttagaagaat acacacttta ttttaaaaac cctgatacta tgttattaga aaatggtact
     3781 aatataaaag atatccagca tatactcgga catgctaaaa cttcaacaac tatggataca
     3841 tatttacatg taactaataa catgagaaac cagacggtaa atatttttga aatcattgta
     3901 gaataaattt gccacccaaa aataattatg gtggcaaata ggtggcaaat ctacttttaa
     3961 gacacaatat aaaagtctga aaccctgtta ttctctaata agtttaacta cagtctcaca
     4021 atgtggcgta tttgggaaca tatccataca cttaaccatc ttaatctcat aaccataccc
     4081 cttaaaatca accaaatcaa caaccaaaga cttaggatta caagaaatat aaacaatctc
     4141 cttagcacca aatccacaaa tatccctaat agcatcctta tgaatgcctg gtctaggagg
     4201 gtcaacaata atcaaatcag gcttgtcctt taaatcctta acaaccttag ccacatcccc
     4261 agcaataaac tcacaattag taagtccatt caacttagca ttctcattag cagcaacaac
     4321 agcttcctca actatctcaa taccatacac tttcttagca gcaccagcca taacctgtcc
     4381 aatagaccca gtaccactat acaagtcaaa tacaacttta tcattgtaat ctccaataaa
     4441 atccctagca atactataaa gaacctcagc tcccttagta ttggtttgga aaaacgaaaa
     4501 tggagaaatc ttaaacttaa gacctaaaat ttcttcttgt atataatctc ttccatacaa
     4561 tactcttaac tcatcacatt ggactgcatc tgctaaacca tcattaatag tatgaagtac
     4621 ccccaccaac tcagatttta aatcaatccc taaaagcata tctttaaact cattcatatc
     4681 aaaatcttct tgagaagaag ttactatatt aaccataatc tcattagtat gaatcccttt
     4741 tctaactaca agatgtctca aatatccttt gtgattcatt gttctataat aaggaagctt
     4801 tttttcattg aaaaactcta cactagaaac taatatcttt gagaagtctt catcaaccaa
     4861 catacactcc tcaacagttt gtatatctat atgctttcct tttttatgaa gacctaatgt
     4921 caaaggtcca ttttttactt catctccaaa agtatattcc atcttatttc tataatattt
     4981 gttttctgga cttccttcta tccctaaaaa ctgaaatcca aataaatctt gctttaaaaa
     5041 taaatccata acttgttttt cttttatttc taattgtttt tcatatggca cagacaatag
     5101 tgtacatcct ccacactctc taaagtgctt gcaagtttct tcagtttcaa gtggtgagtt
     5161 ctctaataat tctatcatct taacttcagc tttcttactt ctaacttttt taactccagc
     5221 tctcaccttt tgaccactta ttccaccctt catatggata actctatctc caacttggct
     5281 taaagatgtg ccaccaaatt ccattttatc tacttcaaat tctataacat cttttttctt
     5341 cacagacatt cctccaattt actatagtat ctttattatc tttcttcaat caattttact
     5401 tcttcatctg ttaattctct atactcacct aactctaaac tttcatccaa ttttaaattg
     5461 cccatagaca atctttttaa gtatactact tttttgccta cgctttcaaa cattcttttt
     5521 acttggtgaa acttaccttc atgtattgta agctctattt ctgattcatc atcacttttt
     5581 aatatattta actgtgatgg catagtttta tatccgtcat caagcactac accttctaaa
     5641 aaagcttcta catcttcttc agtaactact ccatcaattt ttgcataata agtcttaggc
     5701 acatgcttct taggagataa aactctatga gaaagctttc catcattagt taaaactaat
     5761 aatccctctg tgtctttatc taaccttcca acaggaaatg gttcaaaagc taagtatgat
     5821 aaatcaatta aatctaatac tgttgggtca tatttatctg tagttgctga tatatatcca
     5881 tcaggtttat tcatcatcaa atatatatat tctatatata taacttcttc tccattaaat
     5941 aatatctcat cattttcagt gtctacttga gttcctggat ttgaaacttc acttccattt
     6001 actactacag acccttgttt acaatacttc tttatttcac ttctacttcc ataacctaaa
     6061 tttgaaagaa ttttatctat acgttgcttt ttagccatta aaaatgctct ccattctcat
     6121 aatatttttc tttttcaaat actgtaaatg ctaaatccat actttctaca tctaaattat
     6181 ttcttatact atcagttatt attcttgcta ctatatcttg tacttcttgt cctctatcaa
     6241 accaagctac ttcaacaaaa ggatatacat ctgctatttt accctctctt attgcaactg
     6301 actttataca ttctatttca aagtagtctc ttggacattt tacagcttca actaaatcat
     6361 ttatcatttt ttcacttatt ttacatatat cattttcatt aattcctctt atttttatct
     6421 gtggcatagt ttatctcctt tattttaaat ttttagtgaa ttatcatcca cttaattccc
     6481 ttcgataacg tttgaagtgg taacttcttg gtcaagacaa ctattgttat cagtatctcc
     6541 aaactaataa ggtaattcct acccttatag ttagcattat atagctagtt ttcctaaatt
     6601 gtttatattc tttattattt tatttaatcc tattgtcttc tatttaacat tatacttgta
     6661 atttatagtt attacaattt actatatact ttttttgatt taacgttata atataagtga
     6721 tgggtaaatt ttaaaagtta ataggaggag tttaaaatgg cattaattac tacaaaagaa
     6781 atgtttaaaa aagcttacga aggtggattt gctataggtg catttaacat aagtgactta
     6841 gaacaattac aaggtgtttt aaaagctgct aaagctaaaa attcttatgt tatgatacaa
     6901 gcttctatgt cagctgttaa atatgctgga cctcatacat tagttgaaat ggttaaggct
     6961 gcttctgatg aaataggtgt agatgtagct cttcatttag accatggtcc aaatatggat
     7021 gctattaaaa cttgtattga tgctggtttc tcttcagtta tgatagatgg ttctcatttt
     7081 gactttgaag aaaatgttag aataactaaa gaagctgttg aatatgcaca ctctaaaggt
     7141 gttgttgttg aagcagaact tggtgttcta gctggaacag aagatgatgt tacttctgat
     7201 gttcacaagt atactcaacc agctgaggca gttgagttcg ttgaaagaac aggtgttgat
     7261 tcattagcaa tagctattgg aacttctcat ggtgctttca aattcaaagg agaagctaaa
     7321 ttaagattcg atatactaga agaaatccaa agcaaattac caggtttccc aatagttctt
     7381 catggtgcat ctgctgttga ccaaaacgct gttgctacat gtaatgaatt tggtggaaat
     7441 atagctggtg ctaaaggtgt acctgtagat atgttaagaa aagcatcttc tatggctgtt
     7501 tgtaaaataa acatggatac tgacttaaga ctagctatga ctgctgctat cagaaaattc
     7561 ttagctgaaa atccaaaaga atttgaccca agaaaataca ttggtgctgg tagagatgct
     7621 atacaagctg tagttgaagg caaaatagat gatgttttag gttctgctaa ctctataaac
     7681 taatataact tttaaatatt tataaaagaa aagagatgac ttgaaataat taaatttatt
     7741 tttaagccat ctcttttaag ttgtatcaat tatgtatctt tataacattc taattaaatt
     7801 ttaaaaaaca tgtatattta tagtatgttt ataatagtta tgatgtgtta tatccaatta
     7861 ttattttaaa gaacatatat atttacaata tacttaaaat ctacaaaata tattaaaaat
     7921 tttaattata ttgtcttttt aaactggcaa ctaaacatga atgtgtccac tttttatctt
     7981 tctatgaata gtagaaggat atatacctat aacttcagcg gcctttgtta ttgaaccata
     8041 cttatttata gccttactta tcattatttg gtccactatt ttatatgcat cattaagatt
     8101 cataattcca tttaccacta ttggtgataa atcatctgtt tcattatcaa tcatatctaa
     8161 atttatcagc atgttaaatt catcttctcc aattacattt ttagctgata atactacaaa
     8221 tctttcaatg atgtttttta attctcttat gtttcctggc caagaatatt cttctaataa
     8281 ctcaataact ttaggcgaaa cttctacttc tctattgtac ttttcattgt aaagttttaa
     8341 gaaataattt actaatggta ctatatcctc ttttctttct ctaagaggag gtatttttac
     8401 tggaataaca cttaatctat agtacaaatc ttgtctaaat ttaaggttat ttctaaggtc
     8461 ttcatgagaa atattagtag cacttatata tctaacatct atttttatag gcttactacc
     8521 acctattcta gtaatagtat tttcttgtat aaccctaagt aatttttttt gcatctgcat
     8581 tggtaactca cctatctcat ccaagaaaat agttccacca ttcgcctctt caaaaagtcc
     8641 ctttttacct tttttcttag ctccagtaaa agaaccttct tcatatccaa aaaactctga
     8701 ctctaataat tcatttggta tagctccaca gtttatagct ataaaaggtt tgtctctcct
     8761 tgaactatac ttatatattg ttcttgctat tatttctttt cctacacctg attctccatt
     8821 tataaatata gaagaatctg aggctgcagc tctcttaaca acttttttta tattgtccat
     8881 aatcttactt tgacttatat actctgtgtc ttctgatata tcactatatt ttatctgaga
     8941 ttcaagctta ataacccttg aaatatctct ccctgttagt actcctcctg taagctttcc
     9001 cttagaatcc catcttggaa ctgccgtata tgcaataagc ttcccatctg ggtaaacgat
     9061 atttctataa atctttttct tcactttaag catgtttaat attattggtt cttcaactaa
     9121 tccttgtctc acaaggtctg ttatatttct accaagtacc tcagttcttt taaaaggtaa
     9181 tatctcatca ctgacagtgt tcatcttttc aattacccca tctttgttaa acacaacaac
     9241 aacttcatct atatgctcta ttatatcttc aattacttta tcagatatta gagacttctc
     9301 aaataaataa actatattat tttcattatt attatctttc atattgtata tatgtgcagt
     9361 catccttaac tctctgaaag ctattttctt tttactatct gtcagtattt ctgttttgtc
     9421 aaaatttgaa tctaattcat ttatatttct aggctttttt atatctagaa aactaaaaat
     9481 actatctatt agatgattac agtatattat ttcgcctgat tctttacata aaatggctgg
     9541 attttctaca tgttctataa gccctattaa attattatcc attaatattc gcacctttca
     9601 ttaagtaatt tattgaacta catacaaaat ttattgtttg cttacaataa ataccatcag
     9661 cacatataat caactcctta taatattcgt cttttcaagt agtttatttc attaaaacgt
     9721 aactaagata taattttaat gattatagtt tgttaaaaat ttcattttgc ttttaattgt
     9781 attttatcac atatttagta attatttgtc tatttaatac aatttaatta aatttaagat
     9841 ttatttaaaa aaacaaagat aatccttaca gaatataact cacaatttgt aagcaatata
     9901 catataagga ttatccagat tatcttgtat tataaaattt tattcaaaca gactttttaa
     9961 taactgacaa atacacacta gcaataactt atcaaagggt taataattat gttactaact
    10021 aataagactt attcaatcag taatatttat atagtttgta tctattaagc ttttatagct
    10081 tctaataaat catcaacgct atctaatttt tctataagca ttggaactat ttcatgtaag
    10141 tctccaacta ctccatagtc agcgatttct aaaattggag ctgctgggtt tttgtttata
    10201 gcaattatga aatctgatga ttgcatacct gctaaatgtt gtattgctcc tgatatacca
    10261 caagctatat ataggtttgg tttaacagta gttcctgttt gacctacttg gtgagaatgg
    10321 tctatccatc cagcatcaac agccgcacga gaagaaccaa ctactccacc taatttgtca
    10381 gctaattttt taagcatttc aaatccttct ggtccaccta atcctaaacc acctgatact
    10441 ataacatttg catctgtaag agatactaaa tctttcttag ttttaactgt ttctaaaaca
    10501 gtagttctta tatcatcttg agttattttg tagtctaatg ctataacttc accagttctt
    10561 gtttcgtctt tttcagcttt atccataaca ccaggtctaa ctgtagacat ttgaggtcta
    10621 tggtttggac aaatgattgt agccattatg tttccaccaa atgctggacg agtttgtttt
    10681 attttcttat cttctgggtc tatttctaac ttagtacagt cagctgttaa tccagttcca
    10741 actcttgaag ctattctagg tgctaagtct ctacctatat gagttgctcc gaaaagcatt
    10801 atttctggtt ttatttcatc tattgcatct tttattactt ttgtatatgc atcagttgta
    10861 tatttttcta aaagagcatc atctgcaaca taaactttgt cagctccaaa agtgattaat
    10921 tctttagcta atccatcaac atcttttcct aataatattg cacaaagttc tgcatctact
    10981 tctttagcta attttcttcc ttctcctaat aattctataa ctactggagc tatttttcct
    11041 tctctttgtt ctgcaaatat ccatacgttt ttataagaac ttaaatcttt tatatcattc
    11101 atagtttgta ctcctccaac ttatataatg tgcttttgtt ttagaccgat tattatttta
    11161 ctagctattt catcagcttt accttctaag atttctcctt ttcctcttgg ttcaggagta
    11221 aatgatctaa atactttagt tggtgatgct tttaaaccaa cttcttcttt atttacatct
    11281 aaatcatcaa ttgtccaaac ttttacatca tgtttatatg cttttactat tttatcaaca
    11341 gacatgtatc taggtgtatt taactctttt actgctgtta aaagtacagg tgtacttact
    11401 tttattaatt cgtatccatc ttctaattgt ctttgaacta ttatatcttt tccttctatt
    11461 ttgaaatctt gtacatatgt aacttgagga atgtctaatt tctctgcaat ttgtggtcca
    11521 acttgtgcag tatctccatc tattgcttgt cttcctgcaa atattatgtc atagtcacct
    11581 actttagata ttcctgctgc aatagtattt gatgtagccc aagtatcagc tcctccaaat
    11641 gctctatcac ttaataatat tgcatcatca gcacccatag ctaaacactc tcttagcata
    11701 aagtctgctt gaggaggtcc cattgttata actgttatag ttacatcatc atgctcatct
    11761 ttaattttta aagcttcctc taatgcattt gcatcatctg ggtttaatat acttggaact
    11821 ccatctctta taagagtacc tgtttcttta tttattctta cttcgttagt atctggaact
    11881 tgttttacgc aaactaatat tttcaaagtc tatacctcca atttcattag attatttatt
    11941 attttaatac gtttgatgaa attaccattt tttgaacttc tgatgttcct tcgtatattg
    12001 atacgattct agcatctctg tacattcttt cgatttcata atcttttata aatccatatc
    12061 caccgtgaag ttgtaatgct ttataagcaa cttcatttgc aatttctgat gcatagtatt
    12121 tagccatagc agattcttga gcaactctca ttcctgcatc tctcttttgt gctgcatcat
    12181 aaactaatcc tctagctgca caaacttttg tttccatgtc agctatagta aattgagtat
    12241 tttggaattt agctataggc ttaccaaatt gaactctttg ttttgtatat ttaacagctt
    12301 catctaaagc accttgagct attcctagag ctaaggcagc aacacctatt ctaccaactt
    12361 ctagagtacc cattgctatc ttaaatcctt gaccttcttt tccaagtaag ttttcttttg
    12421 gaactttaac gttttcaaat attaagtcag aagtttcagt tcctcttata cccatcttat
    12481 cttcatgagc tcctgttgag aaaccatccc atttactttc tactataaac gctgatgttc
    12541 ctctaagtcc tttacttcta tctgtaactg ctattactat agctacatca cagaatggtc
    12601 cattagttat gaaagttttt ctaccattta atatatagtg gtctccaact aattctgctg
    12661 ttgtttgttg tccacctgca tcagaaccag ctcctggctc agttaaacca aatgctccta
    12721 ttaattcacc tgttgctata ccttttaagt atttttgttt ttgctcttca gtaccattgt
    12781 aaagtattgg taatgaagca agagaagaac cagctgtaac aaaagtagct gttgaagcac
    12841 atcttctagc tatttcttcc attactatag cgtaagaaac atatcctgct cccccaccac
    12901 catattcttc tgggatatta ctgcttataa attttgcatc agctaatttt ttgattaatt
    12961 ccttaggcat tacacctgtt ttatccattt ctgctggtaa agtatctaat tctttactaa
    13021 caaaatctct tactgctttt cttaaaagtt cttgttcttt gttatataac atagcttcct
    13081 ccaattttca tattttatag taaatttatt ttaatgaact tacgctaaac tcatcatctc
    13141 agcaaaagtt tgaatacgag ttctggcttg ttcattattc tgagtttgtt ggtcgatttc
    13201 aacatataaa gtaggtattc cactatcttc tatatctttt ctaactaaag gataatcgta
    13261 ttcttctggg tcacagaatt tcatcataca gaagataaca ccatctatat ctttcttttt
    13321 aacttcatct actataagtg acccacgttt tttcttaggg tcataagcta atgaacatcc
    13381 ttctatgttt gaccattgtc ttgctaatct ttctaacgca tcatcacctg ctggtacatc
    13441 tgttctgaat tgtcttgttt cttgtgctaa atcgtcagct acaactgata tattgttgtc
    13501 ttctaaaatg tctaatatat ctttagaatc agctaatata cctgttaata aaactttctt
    13561 tccagaacag acttcttctg gcatagcatt taattttgct attaaatctt tcactagctc
    13621 agtatgttct tcttttctca taaagaaccc actcttaatt actaagcttc ttattgatgg
    13681 ttttatagta ttagaatgtt tataagctac ttcaacaaag tctctcatag tttttctatg
    13741 ttcattgtaa acttctatac tttcatgaat ttttgcttct tctatttcat atccacaaat
    13801 ttcttcaagt tctcttttta cgcctttgta ctcactgatt aagtatttta caccagcttc
    13861 aagttttcta ttttgtgggt gtactaatga tatatatttt atatgaggta ctgctgattt
    13921 ccagttttgt cctaaacaaa ttagtgtatc acacatacct ggtataataa ctccagataa
    13981 ttcatcataa gcacctttta atccatattc taaacatgat tgcattattg aacatgcaaa
    14041 tgcagggaaa tattgtttag ctaaatctaa ttctgtttgt cctccccata taccaactgg
    14101 aagcattcca gctgcatgta taatttcttc tgggcaataa actgggaaac aacctatagc
    14161 ttttttacca gtttcacttt tatatttttt tacagccgca tttggatttt caactacttc
    14221 tttcatttta gataaaatag cttccattat atctcacctc tattaagttt ttttctttct
    14281 tccattactt caactaaacc ttgaattctt gtttcaaatt gagcattagt gaaagctcta
    14341 gggtctgctt ggtcaccatc aaatccagca tatggtaatc cagtttcttc agctgctctt
    14401 ctttgcattt catattgtat taaactcata agtttacagc ttctgttcat atgatagaat
    14461 gctccatcac atttaccctc tactaaagaa tcaactctat attttgtcat acggtctagg
    14521 tttacattgt taaacatagt actatatgct actgccattc catctaaatc attaacttca
    14581 tattgtaatg cccaagcatg tgggtaaaca ctacctgtca tgttaactcc aaatttagct
    14641 aatgttttca tcttgtatcc tatatatggc caacaaggta taccttccat cattattctg
    14701 tatttttctt cccctctgaa agaagattta ccagttttca tgttgtcctc taattcttct
    14761 ataagtaact taaatgcttc tgtagtttct tttttacctc tagcacaaac tattacagcc
    14821 atgtaagtaa ataagtcaaa tccattcatt ggagaaggag aagaatctgc tggtaaactc
    14881 atagaatact tccataatct tccgttttca gctgatattt tcattacttc ttcaaacttc
    14941 ttagggtcaa atttctttcc tgatataatt tctagttgtt ttatagcttc ttcaaattga
    15001 gctttaatat aatctattct tgattgagta acttcgtctt cattattgaa agttgtatca
    15061 atcattatta aaggtatatc taattctctt gaaatatttt cataccattt tataacttgg
    15121 ttacatatat tgttacagca aagtaggaaa tctggagctg gcatatccaa agcttcacat
    15181 ccaccatttt ctaaaagacc aaaatttgtt cttgcatatg cacataggtc aatagaatat
    15241 cctttagatt cagctatttc acataattct aaagaacctt ttttagctgc tactccagct
    15301 gcttggtttt ctggatataa tacatttaag tcaaatactt ctgctaactc ttgaggaaat
    15361 actgatgttg accaacctac aggtcttcct tcttctttag ctttaaatgc atttgcatat
    15421 tgttcagcta ataaatcatt aattactact ctagcttctt ttttttcaga cattttcatc
    15481 cctcttttta tatatttttc acttcttttt gtgattcttt tgcttcatca aaagcatata
    15541 acgctgctcc taaagcacca gttaattgag gtatatcagg tacaataatt tctgtgttga
    15601 tttctcttgc catagctctt acaataccac tatttctagc aactccacca accataacta
    15661 catttctttg tactcctatt ctttttacta ggctagaaac tctctttgct actgaagtat
    15721 gaatacctgc cactatatct tcaatttttg cattttcaga taaatgtgat ataacctcag
    15781 actctgcaaa tactgtacat gtactgctta ttgatacttc attttgagaa ttcatagata
    15841 tacttccgag ttcagataca tcaacctcta ttatttttgc cattacatct aaaaatcttc
    15901 ctgtacctgc agcacatttg tcattcataa gaaagtttaa tagtcttcca ttattatcta
    15961 attttaatac ctttgcatct tgaccaccta tgtcaataat ggttcttgtc tctggaatta
    16021 tgaaatttac ccctctagca tgacagctta attcacttat ttgcttatca gcatctgaat
    16081 agttcattct tccatatcct gtaactacaa cttttttaat atcttctctt gcaagacctg
    16141 tcttgccata taatttttct aaaactcttg atggtccagt agtcccagta ccagaggata
    16201 ttgtttcaga agctacaata tcttccccat tctttaagat tactcccttt gatgcagttg
    16261 aacctatatc taatcccatt gtgtacatct ttagcattct ccttttaaaa aatctagaat
    16321 tactaattaa tatcttacaa ctttactatc tttaaagtta tttattttct cttcatcgta
    16381 gcctaaagat tttaatactt ctacagtatg ttgacctact tttggtgctg gtgtatattc
    16441 tttaattcct tcatttctaa acataactgg agtattaact aagacacctg tatttccgct
    16501 atcgtatgtt ttcttaaata agaagtcatt tgcccaagct tgttcgtcat ctaataaatc
    16561 ttcacagctt tgaatttttt caaatggtaa gtctgcttct tctaataaag ctgaccactc
    16621 gtctaatgtt ttttctaaca tagcttctcc aactatctta actaaatctt caacatgatt
    16681 aaccattgaa tctatgttat tatatctatc atcttctaat atatattctc tatttataac
    16741 cttacagaat ttgcctaacc acttgttgta ttgtattaaa gctaattgaa tccatcttcc
    16801 atctttacat ttatatgtag tcattaatgg gctgtttgga ttttctcttg ataaaggcat
    16861 ttcatttccg tattgtgctg ttgttatcat tgttcccatt ccatatatag ctgtatggaa
    16921 aagacttact gttactctct cacctttacc agtttgagct tttttatgta atgctgctaa
    16981 acttcctgct gctagtgcta gacctgcata gtggtcacca aatcctgctg ctgtatttgc
    17041 tggagatgtt cctttttcca taacagattg gctaactcct cctcttgcga agtatgcagt
    17101 atagtcaaat cctggtttat cttttaaagg tcctttttca ccatatccta atatttgaga
    17161 gaatattaat cctggatact tatcttttat ttggtcataa gctataccca ttttttctaa
    17221 tgcttgaact ctaacattag ttacaaatat gtctgcttct gataataatt tatgtaatat
    17281 ttctactcct tcttttgatt ttacattaat acttacaccc tttttatttc cattttctaa
    17341 ttcaaacata gggttttcat catctgatgc tggagattta aatgttccac ccataactct
    17401 tattccatca ccttctatag gttcaatctt aataacctct gcaccccagt cacctaacat
    17461 ttttgcacaa catggtgctg cgatgaaact tgaaagttct actactttaa ctccttctaa
    17521 aagcataacg ttttcctcct taatagtatc aattataaaa tttcgattaa atcactcata
    17581 aaatactttt ttctgatatt aactgtctga tgtcaaagtt cctaatctta tctaaaataa
    17641 cttaaaaatt attaaaatta ttttttattg ttttattgtc ttacacctat attgttaagc
    17701 atttatcgtg ccaactttat atttaatcaa aatatcgctt gatttgaatg ttttttaaca
    17761 atatgcaatt gaataatctt tttcatatcg tggcatcttg ccactatcca ttgcattttg
    17821 ctattctttc tatgcttata aaagtttttt ttatatattt ttttatgaaa aagcttgaca
    17881 tttcaaaaaa agttttcatt gctaaactca aaaacacatg ttatcattgt aattaatcag
    17941 caagttagtt aactaatttc aaacttagat aattttttaa taatatttaa tctaaaaaat
    18001 aacaatttct ttgataaatt ttagagtaat tattacatta aataaaaaat tactaaatat
    18061 caaaataaca cagggaaaac aatttcaaaa ctaaattttt aaccttaaaa attttgtata
    18121 aaaaatataa ccttatatgc tacatattat ttctaaatga aaaattacca taataattta
    18181 ataattacag gagggtattg atatgaaaat actagtattt ggagcacgcg attatgaaga
    18241 accagtaata aaaaaatggt ctgaagaaca taaggatgtt caagtggata tttatcctga
    18301 aaacatgact gaagaaaatg tagttaaagc taaagggtat gatggtatat ctatacaaca
    18361 aactaactat atagataatc cttatattta tgaaacttta aaagatgctg gggttaaagt
    18421 tatagcttca agaactgcag gggttgacat gatacatttt gatttagtta atgaaaatgg
    18481 acttatcgtt acaaacgttc cttcttattc acctaatgca atagctgaat tagctgttac
    18541 tcaagctatg aaccttttaa gaaagactcc tctagtaaag aaaaaagtct gtgaaggtga
    18601 ttaccgttgg atagctgaac ttcttggaac agaagttaga tctattacag ttggtgttat
    18661 aggtacagga aaaataggtg ctacttctgc aaaattattc aaaggcctag gagctaatgt
    18721 aattgcattt gaccaatatc caaatagtga tttaaatgat atattaactt acaaagattc
    18781 tttagaagac cttctaaaag aagctgacct tataacatta catactcctt tacttgaagg
    18841 aacaaaacat atgataaata aagatactct agctataatg aaggatggag cttacatagt
    18901 aaatactggc cgtggtggtt taattaatac aggggattta atagaagcac tagagtcagg
    18961 aaaaattaga gctgctgccc ttgatacatt tgaaactgaa ggattgttct taaacaaaaa
    19021 aatgaatcct ggagaattaa ctgacccaga aataaataaa cttctttcta tggaacaagt
    19081 tatattcact catcaccttg gtttcttcac tagtacagcg attgaaaata tagtttattc
    19141 tagtttaagt agtgctgtag aagttataaa aacaggaact gctactaata gagtaaatta
    19201 gtattttata aatatatttt ttcattaatt agctattatc taacaaaata gcctttaatt
    19261 tcccaaatat aagagagtca gctcagtata tattgagtag actctcttat attatttttt
    19321 atattaaact tgtactcttc ttattcatac caaattaaat ttatattaac ttattctaac
    19381 tactcctact ctatacattt tacctatttt tacttttcta attatataca tttgaatggg
    19441 tacaatctgt attttacaaa aaaaacacct aacaaactat gaaaattgta tgattaatat
    19501 taatatattt ataagaaaac ataacaatta tgttagctct ggatttttaa ggagggagta
    19561 tattggaaaa aatgaataaa gttacttcta aaaaaactac ctatattgtt acttcagcat
    19621 tatttgcatc cataatatgc ctgacaatag catatatatt acatattcca gttggtggaa
    19681 acaatggata tgttcatata ggagatgctt ttatttatct agctacaact attttgccaa
    19741 caaactatgc tatagctgct tctgcaattg gtgctggtct agctgattta tctacaggtg
    19801 ctgctatctg ggtaatacca actataatca taaaaccaat acttgtatta tttttcactt
    19861 ctaaaagtga caagataata aataagagaa atatagttgc ttcggttgta gcaggtatag
    19921 taggattagt tttatacatg tttgctgaag gtataattat tggaagtttt acaagtgcat
    19981 ttgtaatgag cttacttggc ttattacagc caataggaag ttttattgtt tttataatct
    20041 taggtatgtc acttgataaa cttgatttta aaaaacgtta ttttaattaa gaatttaaat
    20101 ttatggaggg aaaattatga atatcttata tacaattgaa aatagtatct atgtaaatat
    20161 aactaataca tgtccatgta gttgtgtttt ttgtataaga aacgaaaaag atgaagttgc
    20221 aaatagtggt agtttatggt tggagcatga gccaagtgta gatgaagtaa aagaagcctt
    20281 caataaatac aatttagacg actatgatga aatcgtattt tgtggatatg gcgaaccatt
    20341 aatgagaata aatgaattga tagaggtagc aaagtttata aaagaaaaaa gtagcataaa
    20401 gataagaata aatacaaatg gtctaagtga tttaatacat aacaaaaaaa cagctattct
    20461 gttaaaagat gttatagatg cagtatcaat aagtcttaat gccccaaata aagaagctta
    20521 taatagagtt actcaaccaa agtttggaga aaaatcattt gattatatgt tagattttgc
    20581 aagagattgc aaaaaatata taaaagaagt agctttttca gtagtagatg aaatatctcc
    20641 agaagaaata gaagaatcta aacaactggc aaaaaaactt gatataccat taagagttag
    20701 acataagaat tagcaagtaa aattataaaa cattaagaat cacctgaatg gtatttcagg
    20761 tgattcttcc tcttgtatta acattttaca aaatagattt cataccacac taggaatgtg
    20821 taaatcatcc aaatctttct ccaattatca gagtttccac taatgtagtc attaaaaatc
    20881 tcattaatct catctatgtt aaagaattta tctgctatct cactattgaa tttatctcgg
    20941 atatccttat tatattggtc atcagccatc catatacgaa ttggcacaat aaatcctaat
    21001 ttatttctaa aagcaatctc ttctggtaat gttttgatgc agctgtacga aaggcaattt
    21061 tattctcttt tcctttcact ttatattctg atggtattct ggatgcaata tcaaatattc
    21121 ttgtatctgt aagaggcatt ctgacttcca atccaactgc agtactcatt ttatctatat
    21181 taaaataaat atctccttcc aaccatattt gaatatctac atttgacatg ttagtaagtg
    21241 tatctagttc ttctgtttct tcataaattc cttttaccac ttcaatagga agcacatcag
    21301 gattgtattt cttaagaatt tttcttttct caccctcatt cataatgttt gtatttccaa
    21361 tataaaatgt cttcaaattc tctccataac actctgcctt atggtatata ttatatccac
    21421 caaaaaactc atctgctcct tctccagagt aacagatatt tgtgttttca gctgctgcct
    21481 tgcatccaat agcaaaaacg atagcagatg catctccagt tggttgctcc atatggtaca
    21541 ttacataagg tactgacgca aaatactctt caggtgtaat tatatatctc gaatttttac
    21601 acccaagaat attagctgtc tgttgtgcta attttgattc atcaaaacgc tcttcctcat
    21661 aaccacatga acctgttttt tctatatctg acattgccaa tatataagat gaatcaacac
    21721 ctcctgatag gaataactct gcagtttcat tctctgattt tacctctggc ataattttct
    21781 gaagtgttgt atgaatttca tccgtccatt cctcaataga cttgctgtgg tcaggatgaa
    21841 attcaggttt ccaataacga ccaatacata ctgttttatt ctgatagaca aggtaatgtc
    21901 ctggcataag cttctttact ccacggaaga atgtattttc acctgctaca tatgtgaaag
    21961 acatataaat ctgtaacatg tcttcattta actctttcac aaatcctggt tgctccataa
    22021 tcttacgaat agatgaacca tagagaagct tcccattttc agtctcataa taatagaaag
    22081 gttttactcc aaactggtct cttaggcaga agagtttctt ttccacagta tcccataatg
    22141 caaaggcaaa cattccatgc atgtgatttg ccatatcata tccccatgtc ttatatgctt
    22201 ccactaaaat tgctcgttca cgctcatctc tacataatga agaatcgatt ccaagttctt
    22261 cacagagaac tttccagttt cgaatatgtc cattgtattc tagaattttt atcatatatg
    22321 tgtcttttcg tgttaaatac ttttcttcta aatttatcat atgtgtatcc tttcgtatta
    22381 aaacatttaa cttctaaatt tattaaatgt ttatatatat ttattcactt ataatcactg
    22441 aaaaatcgac ttttttcaaa gtaaattctt tttgaattag tactaatctg ctctttatta
    22501 atggcataaa tatgattatc aagtattatc agtgttataa cattgaattt tttattcttc
    22561 ataaatattg ccccctttat attaccaact aaatataata tatcttatgt tacttacata
    22621 ttctttaaga aattctgaag attttataaa gttttttgta ttataattaa ttaaaaataa
    22681 aattctagtt ataaaacata ttttccatta aacaaaaaaa tagttaaaat aaattcataa
    22741 ccacataaac ttattttaac tatttgtata ttttaattat aaatattaac ttaaattttt
    22801 aacaggatac actcataaaa taaacataat gaacaacaaa ataatatgtc tcagtttctt
    22861 tatatacttt accttctttc aattttctac catgtagacg tataagataa tattagtaat
    22921 tcactctatt gcttaactcg tgcgatatgg acaaccaaga aagctatttc ctcatttgtt
    22981 aacttttttc catatttctt ttctaaaaaa tctctaactt ttaatgcaat taacatttct
    23041 tttggatttg accttttcat ttgattaaat aataaatcat caccactgct taacatacta
    23101 tctgaaaaaa atctttccac aaaaaatttt atatgtgtta taaatctcat ataatgcata
    23161 ctctttttat ctaaggttct attcaaagaa aaaacaaaaa tattaattat ttctccaatt
    23221 actttggcat acttaatcgt atcatatgaa tttccatctg aagccatagc atttgcaaaa
    23281 tggaaagcaa tgttagctgc ttcttcctct ggtaattgaa tgcccaatct ctcctctacc
    23341 atataaattg caaccattcc aaccttaaac tcatttggat aataattttt tatttcccaa
    23401 aatactcgat ttgtaatttt tattccttta cgcatccttt caattgcaaa gttaaaatgg
    23461 tctgctaata ttaagtataa gtttttatta aaagatgagt tcaataactt ttctgcctct
    23521 actattattt cctgtgttat ctttaaaatg tcgacaggaa tatcatccat taattctaaa
    23581 aattgttttg attttgtatt ttcaacaggg acaaacattt gattatcatt ggaaccacaa
    23641 atatattctc ctgttttttt accatatcca attcctttcc ctagcaaaat aaattcatta
    23701 tcctttgtgt catgaactaa aacaacgctc gagttcaaaa ctttctttat tatgtagttc
    23761 attttatttg ctcaccttct attggtcatt taaaatctat actattactt tcaattacct
    23821 ttttatacca ataaaaacta tctttcttat atcgattata tgtccccttt ccataatcat
    23881 cagcatccac ataaatatat ccataacgtt ttgacatttg tttcgttgat tcactgacca
    23941 aatcaataca accccatgaa gtatatcccc aaagttcaac accatcttca ataatcgcat
    24001 ctaacataca tttaaagtgt tcttttaaat aattaattct atattggtca tgaacttttt
    24061 tatcttcagt taaaatatct ttggctccca atccattttc aactataaat aaaggctttc
    24121 tgtatctatc atataattca atcaaagata tacgtagacc tattgaatca atttgccaac
    24181 cccattcact catttctaaa taaggatttt ttacagctaa taacgtattc ccaggtgtaa
    24241 tatctaatcc agttgtatca gctgcctcac aagaagacat atagtaagag aatgaaataa
    24301 aatctactgg atactttttc ataatttcat catcatgttc ttcttttact atttgaatgt
    24361 tattattttt aaaatacgac agtaaatata ctggatactc accaaaaacc tgcgtatcac
    24421 tatatgcata aatacttctc atttttcgtt gagttgccaa aacatcttct ggtctacatg
    24481 tgtatggata atacgttaat tttgttaaca tacaccctac ttttgaattt ggaataattt
    24541 catgacaaat ttttgttgca agggcactag ctacaaattg atgatgcata gcttgaaaaa
    24601 taacttcctc aaagttttta tccttaaaac ggtctcgaac taaaccacca gtagtgtacg
    24661 gatgacgaat catagaatca acttcattaa atgtaagcca atatttcact ttgtttttat
    24721 atctttcaca gatagtttct acatacctaa caaacatatt gataacttgt cgtgaatacc
    24781 atccatcata gtttaaaacg atatttaatg gtggttcata atgtgacata gtaacaagtg
    24841 gttcaattcc ataacttatc aactcatcaa atacatcatc ataaaactgt aaaccttctt
    24901 catttggctc tttatcatct ccatttggaa aaatacggga ccaagcaata ctcattcgat
    24961 atgtcttaaa tcccatttct gccattagag caatatcttc tttatagtga tgataaaaat
    25021 cactaccatg acgttttgga taatttactt catcttcagg atgtgctaat ccttcttcta
    25081 tatcttttgt tgtgatttca ttattagatt tataatcttt cacatctgca tcaaagtgtg
    25141 cctttgctac atctgataca gaccaccctt taccacctaa attccaacca ccttcaaatt
    25201 gattagcagc tgtagctcct ccccaaagaa atccttctgg aaactttctc atatttatat
    25261 tcctcccttt acatcaaaca agatacttcc tttttttaca ttgccataag actggtttaa
    25321 cactttataa gcataatctg ctccattatt gtttacaatc ataacagttg aatctaaatt
    25381 agcatgtgag attttgtcta aatcaaactg aattaataaa tctccttctt ttacattatc
    25441 gcctgtctta acaaatgttt taaatccatc tccattcata cttacagtat ttattccaat
    25501 atgaatcaaa atctcagccc cattttttgt tcttaaacca attgcatgtt ttgtttcaaa
    25561 taacatcaca acttctgaat cacaaggtgc gtataaattt ccattggtcg gtataattgc
    25621 aactccatct cccaaagtct tacttgcaaa tagttcatca ttaaccttac ttaaatctat
    25681 tacttttcct tctactggag ttactaagat atttacttct ttttcttctt ctagctcttc
    25741 ttcaacaaca tctccaattg atgactctac tgtatttgta tcttccttcc aaataatcag
    25801 tgtaataata aacgagccta atattgcaat aacaaaacca atacttgcaa aaatcaaatt
    25861 gtttccattg tttgggtcaa taaacatact catactggca agccctggtc caacaattac
    25921 aaatcctttt actgcaaata atcctaaaaa tgtaccagaa attgcacttg agaatacaac
    25981 acctaacatt gctcttttat gttgtaaagt aataccatat aaagctggct ctgtaattcc
    26041 catcaaggca gaaattcctg cagataatgc tgtttgtttt aatgtttcat cttttgttcg
    26101 caaggctact gcaaaacaag caccactttc agaaatattg tgggctaatg aagatgtcat
    26161 atataaagct tcataaccca actttccaat tgtattaatt gaataaggta ttagtgcttt
    26221 gtgcattcct gttgcaacca taaatggaag aaaagcagca agtaatccta caactaagaa
    26281 tcccattttg ttatataaga ataaaataat ggttgtaaaa attgtaccaa cgttatatcc
    26341 taaaggacct aaaatagtta gagtaattgg aacagtaatt gccaaagaca tcataggaac
    26401 aaagaaagtt cgaattggtt ttggtgaata cttgttaaaa attttctcca ttgttgccaa
    26461 gaaagacaca cataagatag ccgggaaaac ctgtgcatta taggcaatgt ttggaattgt
    26521 aaatccaaat agttcgacac cttcacttaa agcagttgtt gttgctggaa gcaataagta
    26581 tcctacagcg gcaatagcta ctaaacgatt acatttcaat acattggcag tagttacagc
    26641 taccataaga ggtagaaaat agaatgttgc atctgaaata gcaactaata atgtatatat
    26701 agtagaatct gattttaaaa tattaaacat tgctaataac atcaacagtg attttaaaat
    26761 accagctcct gcaatagcaa aaatcagtgg ttgaaaaata ttaataataa attctataaa
    26821 ttttgttcct aagtttattt tttcttcagt ttttacagta ctatcatttg tatctaaagg
    26881 gcaaactttt aaaatttcat catacacatc aacaacacta tttccaatga caacttgaaa
    26941 ttgtgcccca ttaactatac tcataacacc ttgtactttt tttaaagcat cctgattgac
    27001 tttacttcta tcaatcaact taaagcgtag tctagttgaa cagtgttcta aagctaaaat
    27061 attttttgaa ccaccaactt gttcaataat gtcaatggca gtttttttat aattcatctt
    27121 gtaatctcct tctccataat tttttatgaa tggccattca agatgcaaaa aaggcagaac
    27181 ctatataaac accttgaaaa atcaaagcaa tatattcgat cctgcctgca ttaccagtaa
    27241 catgtcttct atttatacta ttttgtatta ttatattaac atttgcctaa aagaattgtc
    27301 aatacttttt taaattttct gatactaact aatagcacct ttataattca ttttttatgt
    27361 caattaaagt aacagtagcc acccaccaat tagtatcaaa attgaacctg gtattttttc
    27421 ttttatattt tctttgaata taaaatgagc aagtattaaa gttattatca tagatacttg
    27481 agaaaatggc tctgctatac taagttctag attatttaaa gcaattaata atgctaaata
    27541 agaatatcca ttaatagcac cacttaaaat tgaaagcccc tttttattag taaaaatctc
    27601 acaaattatt ttttgtttct ttttaaatgc taaaaagata aataaattta aacctacgaa
    27661 aaaatacagt atagttgaat ataatatagg agatacttgt acaaaaaaag ccttatccaa
    27721 tactcttcct actgactgca aaaatatgta taaaaacatt aatctacatg gtaaattgtt
    27781 aaaaattaca gagacattct ttaaaaaaga gcttactttt tttaatataa acactccacc
    27841 aatcataatt atgattcctg caacttttgc taaacttaaa ccttcaccta aaaatataac
    27901 tgataaaagc agtaaaaaca atgaatttaa actatttatt ggagtaacaa gtgaaacttc
    27961 cccagttgct aaagacgtta catacgctac tgaaccaatt gaatagacta aactacttat
    28021 ataacatggt attaaaaacg accaatcact aactctatcc attatgctaa atggaagtaa
    28081 acatactccc cctataaaga aaaatagaaa tgatgaagct atatttttat aaatatctcc
    28141 ttcttcatca cctaataatc ttacaactac tctttcaaaa gctaatagca ctactctaat
    28201 taataatgca aaataagata atatcatttt tgacctcgct taaaaattaa tccgacttat
    28261 tgttatatta actgtataaa actaccatat aggtaagtct tttggatttt ttaatatttt
    28321 atgtttaaat acaggtacat taagtttttc acctagttta cggcattgct ctttataggt
    28381 accttttaat ttatcatgaa aaactataca atcaattcct ccttcaatac tatttataca
    28441 cttttctagt ttctcaaatc cagattcatc atcatacatt ccacttacaa tccattgatt
    28501 tggcaataca tgtccaattg atatgttata ttctttattt tttataatat ctgagaaaga
    28561 tttctcaaaa tgtacccctc caacacataa caaagtcttc aaaggttcat cacaatcaaa
    28621 tactctaatt aatgattttg ccaatacctg tattgctata ctattattaa aactatcact
    28681 actacttcct atctcaatat ccaacatagg tacagaatat tctgtaatta atttagattc
    28741 ttcaccatat gttgttccag accagtgagt tgcttctgtt aatgtagtaa attcatcaag
    28801 tagattttca ttttttatat cctcaatagc attgattaga tttttaaagt atcttggatt
    28861 tgaatttcca aattctcctg ttggaacatc tccaattgta tgagctgtta ggatatgttc
    28921 tggagcattt tctccctcat gccaatttac aactcctgca aaatcataat ctctaaaatg
    28981 tctatttaaa attggaagat aatatttata attatgactt attacatctt ttgtttttac
    29041 aaaatgaaat aagttattgt ttttatcctt aaactctaat acaaaattat catcaataac
    29101 aatatcagtt tgatttaaat ccattatttc ttcacaacac tttatcacat tactggctac
    29161 tgggtctttc tttaaatcac tacaaaagaa aaaaactgct tttttattat tcatccataa
    29221 atcacactcc tataacttaa atataatata tcttcatacc taaaatcatc taaatatcac
    29281 tctaattcca ttaaattatt tatatataat atactaccat actcatttta gctatacctt
    29341 tgcctgagtt tctatatata tgtgatacat cagctttaaa tcttatagaa tttccactag
    29401 atacaatata atcttctcca tttattttaa tggttacttc gccactaaaa acagttataa
    29461 actcttgtgt tcctggaagt tcagcatttg aatctaaatt tccaccttct tctatttcaa
    29521 tcataaatat ctcaaatctt cttttggagt caaatggaaa tattggataa cttatatact
    29581 ttccattatc ttcaataaaa tggtctatat cacttttttg aatcaattct atgtcacttt
    29641 cctgcctctc catcaatgat gtaaatgaga tttttagtcc attagttatt ttcttcaaag
    29701 tagatatagt aggatttacc tcacactttt caatttgaga tagcatactc ttacttacac
    29761 cactaagttg tgcaatcttg tctaaactaa gatgtttttc tttccttatc ttttttaaat
    29821 tttcagcaat tatttcattt aaactttgca taaatacccc ctaatacata ctaatataag
    29881 ataaattatt ttgattatta aataaactta gtaatttaat agaaactttt tatccattat
    29941 aatgtacatt atgtttaata tacattactt tttttagaat gtaaatagtt ttctgaaatt
    30001 ttgtgaaaat gaacaaataa aaaactagta acctatattt ttacaaggtt actagctttt
    30061 attataataa tatttcattt taactataaa acttagatgc acctataagc tgtctcttag
    30121 aaacaatctt agctaggttt gctaatgaag aaatttttat atctttaaaa gaaactaaaa
    30181 atacaaactt aaaatctgta aattcttgat ttatattgta tatatcaaaa taacatctca
    30241 aattatcaaa taagtaatta tcctgtaagt ctgcttctat ctcatcagta gcatctttta
    30301 aatacgctct tacatcttca aataaaacac tgaaataaga ctcatctatt tcttcaccta
    30361 actcttccaa tatttcttct atatctaaat catccatatc aaaagaattt cctgtcaact
    30421 ggcaatcaaa taccaatata ttttcttgat ttatagtatt tgatatatct tgtacatatt
    30481 cgaagtctgg acgtaattct aaaatgtctt ttatttcact gctctttaca tggatttttc
    30541 cttttctatt ttcaattttt aaatctatca tatgctcccc ctttcaatct acaaatcttt
    30601 aaataccttg ttttataatc ttttcaatat ctatccaatt actaactcta actatatttt
    30661 gatgtttaac atctttatta tagttagtat ccagaagtat tactttaaca ccatcatcag
    30721 ctagttgcac tgagtttaaa ggattatctt ctataaatat gtcacaactc agttctcttg
    30781 ccttttcaac tttataatca cttcctaata agtaaacatc tatatctgaa aatccttgtc
    30841 tcgatagcca atttttagtt acatcagtta aacactcatg tctagccgtt acaaaagata
    30901 aattatgtcc tttagataat gtgctaatta cctctgtagc accctctaca atctttgctt
    30961 catcatatga gtgtatatac ttattattaa actccgcata cacatctctt attcccgaac
    31021 catacaattc ttcccaatta tgtgttatac actctgcttc agttatattt ttattaaaga
    31081 tatcatttag gtatggaaga aaatgataag ggcttgttat tgttccatct atatcaatac
    31141 atatattcaa tttgttcatt tttacctcca tgtaacattt attgatttga ttaatcaaat
    31201 attatagcac agctttaatt ataaatcaaa actctggata tgactatacc tatataatac
    31261 caaaaagctt gcatatttaa gcaagctttt cgtaaatttt acatttttaa ctaatatata
    31321 agtttttcta aggttggttc cactccaaat tgtgatttca gttctttata ttcttttaat
    31381 gctttgtcat tattcgtttt agtttttatc gctcttatca ttaaattttt tggtgtatca
    31441 agtggagata tgtattctac tacagaagta tcatatccat tgccctccaa taacaatgtt
    31501 cttaaaccat cagttatcaa atctgcaaat ctagctttaa atacaccatg ttttaatatt
    31561 ggttccatag cttcatatct atattgccct aataactcct tatgacaaca tggtactact
    31621 actatagctt cagattttgc tctaattcct agacctattg ccatatctgt agctgtatca
    31681 caagcatgta gacttattac aaggtcaaca tccctattag gtgtataatt agtcaaatcc
    31741 tcttttataa atgacatatt tttataaccc aagtttttag ccatattttt tgatgcttct
    31801 ataactacat ctgaataatc tattcctata aaataacagt ttttcttcaa tacttctttt
    31861 atataaaaat ttaagacaaa gcttaagtaa gattttccac aagcacaatc caagatagtt
    31921 atacagtctt tatcctttat ttcttttaaa atactatcta tcaattcaac aaaatggtct
    31981 atctgattgt attttcttat tttatcattt tttatcttac catcttttgt aagtactcca
    32041 atttctttta aaagtgcatt tgcttgtcct acttttacat aataatctct gttttttatt
    32101 tgagatgccg taaattcatc tattttaggt acttcttcct tattatctaa atattttaca
    32161 tttaccttct tattgtctcc ttcaattaca acaatagttc ctcgctcaac atatttaaat
    32221 actaatccat cataattttc tgcctcttta gaaatattct taagcaactc attaaacgta
    32281 tataaatctg attttccttt aaaattaaat ttatatttat tatcttcctc tattgcaatt
    32341 cctttaaact cttttcttcc agatttaaaa atcacctcta actcaataaa aaaatcccta
    32401 ttatcaaggt ttctttgagt aatccccata aaaaacatat ttagttttcc tatactctgt
    32461 ttattcatca taatctccct tttaagttat atccttaaat cttatcaatt aatattattt
    32521 gtttctgaat tatttatttc ttcttttaaa tcgttcaatc tatttttaaa actttctatc
    32581 tgcttatctg ataaatcaag atattctgtt atcttcccta tatatttagg gcttttagta
    32641 tttattaatt tcaaagcact ttccatagat ttttctctaa gctcatatgc tttctttacg
    32701 tcatctctag cattactcaa tgtttctgta tacttctcct tagaaagttc tggaatctgc
    32761 atatttttat attcttttac aacttcttta cacttgtttc tggcatttgt aacatctttt
    32821 tttatactag ataatttagt tatatttttt gctatatcct tagtgtaagg tatacattct
    32881 ctcattggaa ctaaagctgc tctttctata ttataaattt ctttcttaaa aattcctata
    32941 ctttccatat ctattttttt tatatcttca ctattttttt ctttacttgt atatttatta
    33001 ttttcttttg tattatcttc ttgtttttct gatttattat tcactgaaac attactatca
    33061 gaattattct tttcttttat atcattactt ccttcttcat tactttcttt attttgtata
    33121 tttctatctt gtttgttgtt taaattttta ttatttgata tttcttcatt ctttttatta
    33181 tcctgtttta aatcagtact ttctttttcc ttaaaatttg atacatactt ttcatcatat
    33241 gtctcatcag aaatataatt gtgataatac atagactctt ttattttatt aagtccactc
    33301 atataaatat tacttatcat tattgttgta gctaatacca cataaatact actgtagata
    33361 caagacctct taaaattctt gtaatttctg aatatcacta ctaaaggaat aagatataaa
    33421 aatataaaaa ctaatatcca cctcataagt cgtgtctcct ttctcaaaac cgaaatccct
    33481 caaatattta tttttaatca tgtatcttat agtatttacc aatttatgtt ttttaatcgt
    33541 gaacttttat taaattaaat tctgtatagt cacaagatgc taatgtatat tctactccat
    33601 ttcgaatccc cttcaatccc attttaaaag attctttacc atgcaagtga ccataaatca
    33661 ccttttcaac attatattct tcaaataact ttgtaaataa agattcttcc aatttatcat
    33721 tcgtaggagg ataatgagta atcacaatta tttttgagtg accactttta cgagcagatt
    33781 ctaatgatag tctaaatcta tgttcttctc ttttataaac tttttcatca gtctcatcaa
    33841 atttgacatc attaggacat atccagcccc tacctccaca aattgcataa tctttatatt
    33901 cataaaaatt tgtctgaata aaacgcatgt cttcatatag cttgtttaaa cttgtaacgg
    33961 ttgtccacca gtaatcatga tttcctttta taagtatttt ctgacctgga agtttgctta
    34021 ttatatctaa atctttttta gcttcggata aattaattcc ccaagatgta tctcctagta
    34081 ctaagaccat atcttcttcc ttaacaactt ctttccaatt atctataatt ttcttttcat
    34141 gaccatccca attacttcca aagatattca ttggcttatt gactgatgtt gaaaaatgta
    34201 aatcacctat agcatacaaa ctcataatat ccttcctttc ttaattacac taaataggct
    34261 gtctcttttt agaaattatt ttccattaag aggcagcccc attaatattt agcaaatttt
    34321 ctacaagtag tttttactga actactttat catctacctt agtatcctta tattgctcta
    34381 ataatatatc tatttcttgt tttaattcca aaatttcagt tatattttta tctgtttcag
    34441 ttctatcaag ttttctttgg tactgcatag ctttatgtgt atcacccaag tcatataact
    34501 cttgtattct atttagagta tctctaatag ctatagactt catttggtac atagcctgag
    34561 ctttcattat gtcctctctt atttcactca tttcttggtc taaaagaaag gcagcatcag
    34621 atgctcttct aagcctttca gcaagagtct caggtatgta atggtcatat ttatatttta
    34681 atgaatgttc tattgtagcc cagaaattca ttgcaagagt tcttatttgt atttcacata
    34741 taatttcctt tgaacccgca atggagttta tagggtattt tattataaca tgatagcttc
    34801 tataaccact atctttgtaa tttgtaatat aatctttttc tcctattata gtcatatcat
    34861 ttcttacttt tatcaaatca actatagcat atatatcctc aacaaactgg cacattattc
    34921 ttataccagc aatatcatca atttcagttt ctatatcttt tgcatttatc ctttttaact
    34981 tagatattat ggaagatatt ttttttgttc tacctgtgac aaactctatg ggagaatatt
    35041 caccttttgc taaatattct tttcttatat ttttaaattt tattttcaat tcctctactg
    35101 catgttcata aggtgctagt atctcattcc atttttcgta ttccatattg ctcacccttt
    35161 atttgttttt tatgaccttc tttattttat cataatttat tttgtttttg tatagtaaag
    35221 caattctcca ttttccaata tataccctat ttcttctaaa tcaactaagt aacttatgac
    35281 agatactaac gaagatttaa aaaaatgata ctctttataa ttattgctta aattattgtt
    35341 atttataatg ttttttaata aaatttctaa agatttcggt tctacaagca actctcttat
    35401 ttgatataaa tattttttta aagcattcaa atgtttttct attaatttat aagaatcttc
    35461 tttcgatata acttgcttgc catgccctaa aactaagtac tcaaaatcta tattttttaa
    35521 tttttctaat gaatttattt gttcttgtat atcatataga aacaagaaat cgtattttga
    35581 taaaatttca tctcctatca ataaatcgcc aacaaaaatc acattatcct tcgtcaaaac
    35641 agctatacta ccaggtgtat gaccctgaaa ttcaattata tcaaacattt cattgtttaa
    35701 ttcaattttt ccagcttcta tagatttatc tatttttata tcatccaaca ttttattttt
    35761 taagatatta tccataaata cattgctctt tcccccaaca atatactttg aaaacaattc
    35821 tggattttct atatataatt tatcgtattc agatgacatt atacacacat ctttataata
    35881 ttctttaaat tgattacaag ctccatagtg gtcatcatga ccatgagtat ttataatata
    35941 tctaacctgt atattatttt catctaatac tttatttact ctcctaggtc ttgaaccaca
    36001 taaccctggg tctatcataa gtgctgtgtt atcttcaaat acatatattc ctgtattcgt
    36061 gccacctttt ataaaaaagg tatttccttt tacttttgta agattcacct tcttcacctc
    36121 attttgacaa tatttatgat acaatttatt acttactaat ataaaactat acaagaacaa
    36181 tcctttttat tctatctata gttctttttc ttattttgta ttctttagat atccttattt
    36241 tcacattata tgctaaattt ctataaagta atgactctat aaaatattca actatacctc
    36301 tatccctaaa gtctatatct atatttccac ttgaataaat atttgagtct aatatcataa
    36361 gctcatcaaa aaagcttaat ctcttagatt tacttaaata atctttattt ggaataaatc
    36421 tatcacaata atctatcctg taatttacta cttcatcatt tatttcaaat ccatattgct
    36481 ttttcattaa ctctctatag ttattatttt tctcaataac attatctaaa tttttattat
    36541 aatcctcttt tttccaatgt ccaaacatcc tacaatttaa tggtctaact tcatatatta
    36601 aacatctatt attagtatct ttaaatggac atgggttctt tcttgtatac tcctcaaaat
    36661 aataatctaa tattttactt atacagcttt tttttaaatc aactctatct tcaagataac
    36721 aaaatatatt caaaaactca attaaattta tacctactga ctccatacaa caatttccac
    36781 atccagaaca atttcctact ggcaaggact tatatacatc atttagtttg tcaaagagct
    36841 tatttttaat ggaataatct atacaattta aaatatcttt attttttata ctagtcatta
    36901 ttattactcc ttgttataat tattaagtta atacaaacaa ttattataac atatttttta
    36961 aatttaatcg catatggagg tattttatga atagatatac aaaaataatt aatatgatgg
    37021 gaagttatta cacaaaagac tttgaaaaag aaaaaaagaa tgtaataaaa gttagagaag
    37081 ttaaagaaga tacagttaga aaatttttct tacaaggtga ctgtgaagtt cttgtagtat
    37141 ttgaagacac tgggaaagaa atacttattg atgacttttc tcctgaagaa gatatcaaaa
    37201 aatatttagg agcaaaattt ataaataaaa aaagatagtt atcaaaaata attctaaaa
//
LOCUS       DAEPUT010000039        34238 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.040, whole genome shotgun sequence.
ACCESSION   DAEPUT010000039 DAEPUT010000000
VERSION     DAEPUT010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34238
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.040"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..726
                     /locus_tag="KRL22_002047"
     CDS             <1..726
                     /locus_tag="KRL22_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005343085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1272536.1"
                     /translation="AAFYTAIQDDCIRKNPFDFQLNTVLEDDTEPKEPLSPTQEAAFL
                     SFVQHDKVYQKYYDEIIILLGTGLRISELCGLTEADIDLGKQLINVDHQLLKIADVGY
                     YVETPKTKSGNRVIPMSEKVLEAFQRVLNKRKYAQPVILEGYTKFLFLNRNGLPKVAV
                     NYESMFRGLVRKYNKTQKVALPKVMTPHTLRHTFCTTLANAGMNPKALQYIMGHSNIN
                     MTLNYYAHTTSETSITEMKRLIA"
     gene            1007..1855
                     /locus_tag="KRL22_002048"
     CDS             1007..1855
                     /locus_tag="KRL22_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272537.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMSNNINSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNM
                     GMPNNISNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQATNIEE
                     FDEEEM"
     gene            complement(2292..3380)
                     /locus_tag="KRL22_002049"
     CDS             complement(2292..3380)
                     /locus_tag="KRL22_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272538.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            3505..4233
                     /locus_tag="KRL22_002050"
     CDS             3505..4233
                     /locus_tag="KRL22_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBH1272539.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(4435..4926)
                     /locus_tag="KRL22_002051"
     CDS             complement(4435..4926)
                     /locus_tag="KRL22_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272540.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(4937..5380)
                     /locus_tag="KRL22_002052"
     CDS             complement(4937..5380)
                     /locus_tag="KRL22_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272541.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(5370..6209)
                     /locus_tag="KRL22_002053"
     CDS             complement(5370..6209)
                     /locus_tag="KRL22_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272542.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            6979..7425
                     /locus_tag="KRL22_002054"
     CDS             6979..7425
                     /locus_tag="KRL22_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002599264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1272543.1"
                     /translation="MIKFEKLNIINNKDMKEILDTWESSVRATHDFLSEEKIISIKPQ
                     VKEGAKYVSNFLCVRDKKGLIKAFMGIHDFKIEMLFVGNYSIGNGIGKRLAEYAIEVL
                     NVNYVDVNEQNQQALGFYKHMGFKVFKKSEFDEQGNPFPILHMKLK"
     gene            complement(7655..7795)
                     /locus_tag="KRL22_002055"
     CDS             complement(7655..7795)
                     /locus_tag="KRL22_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272544.1"
                     /translation="MKNENISYLALGLCFGVILGSLFKNLAIGLSFGLVIGVVLDSKK
                     NK"
     gene            complement(8356..9741)
                     /locus_tag="KRL22_002056"
     CDS             complement(8356..9741)
                     /locus_tag="KRL22_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1272545.1"
                     /translation="MENLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KEYLKKYGFSIDELEGMDTAFAASYGEGRPVIAVLGEYDALDGLSQKVSTIKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDSCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTSMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKY
                     TVGSFEYTPII"
     gene            complement(9914..10657)
                     /locus_tag="KRL22_002057"
     CDS             complement(9914..10657)
                     /locus_tag="KRL22_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBH1272546.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(10677..11939)
                     /locus_tag="KRL22_002058"
     CDS             complement(10677..11939)
                     /locus_tag="KRL22_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1272547.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIGGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(12123..13121)
                     /locus_tag="KRL22_002059"
     CDS             complement(12123..13121)
                     /locus_tag="KRL22_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBH1272548.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(13105..14616)
                     /locus_tag="KRL22_002060"
     CDS             complement(13105..14616)
                     /locus_tag="KRL22_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH1272549.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(14670..15632)
                     /locus_tag="KRL22_002061"
     CDS             complement(14670..15632)
                     /locus_tag="KRL22_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH1272550.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(15680..16570)
                     /gene="rbsK"
                     /locus_tag="KRL22_002062"
     CDS             complement(15680..16570)
                     /gene="rbsK"
                     /locus_tag="KRL22_002062"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBH1272551.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(16612..17625)
                     /locus_tag="KRL22_002063"
     CDS             complement(16612..17625)
                     /locus_tag="KRL22_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1272552.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(17854..18831)
                     /gene="bioB"
                     /locus_tag="KRL22_002064"
     CDS             complement(17854..18831)
                     /gene="bioB"
                     /locus_tag="KRL22_002064"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBH1272553.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            complement(19037..19300)
                     /locus_tag="KRL22_002065"
     CDS             complement(19037..19300)
                     /locus_tag="KRL22_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272554.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(19370..20443)
                     /locus_tag="KRL22_002066"
     CDS             complement(19370..20443)
                     /locus_tag="KRL22_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH1272555.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(20691..21449)
                     /locus_tag="KRL22_002067"
     CDS             complement(20691..21449)
                     /locus_tag="KRL22_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272556.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTIYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISVVCLLAAVILFNKKPV"
     gene            complement(21446..22363)
                     /locus_tag="KRL22_002068"
     CDS             complement(21446..22363)
                     /locus_tag="KRL22_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272557.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(22363..22563)
                     /locus_tag="KRL22_002069"
     CDS             complement(22363..22563)
                     /locus_tag="KRL22_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HBH1272558.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(22568..23662)
                     /locus_tag="KRL22_002070"
     CDS             complement(22568..23662)
                     /locus_tag="KRL22_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272559.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(24172..24312)
                     /locus_tag="KRL22_002071"
     CDS             complement(24172..24312)
                     /locus_tag="KRL22_002071"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HBH1272560.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDIYPDSGWGFMTWDEN
                     GE"
     gene            complement(24622..25929)
                     /locus_tag="KRL22_002072"
     CDS             complement(24622..25929)
                     /locus_tag="KRL22_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1272561.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVSGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(25994..26473)
                     /locus_tag="KRL22_002073"
     CDS             complement(25994..26473)
                     /locus_tag="KRL22_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HBH1272562.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(26520..27383)
                     /locus_tag="KRL22_002074"
     CDS             complement(26520..27383)
                     /locus_tag="KRL22_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1272563.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGALF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(27383..28138)
                     /locus_tag="KRL22_002075"
     CDS             complement(27383..28138)
                     /locus_tag="KRL22_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1272564.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(28165..28653)
                     /locus_tag="KRL22_002076"
     CDS             complement(28165..28653)
                     /locus_tag="KRL22_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1272565.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(28671..29072)
                     /locus_tag="KRL22_002077"
     CDS             complement(28671..29072)
                     /locus_tag="KRL22_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBH1272566.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(29075..29572)
                     /locus_tag="KRL22_002078"
     CDS             complement(29075..29572)
                     /locus_tag="KRL22_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1272567.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQTDDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(29596..30000)
                     /locus_tag="KRL22_002079"
     CDS             complement(29596..30000)
                     /locus_tag="KRL22_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1272568.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(30230..32797)
                     /locus_tag="KRL22_002080"
     CDS             complement(30230..32797)
                     /locus_tag="KRL22_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1272569.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            32963..33706
                     /locus_tag="KRL22_002081"
     CDS             32963..33706
                     /locus_tag="KRL22_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH1272570.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
BASE COUNT        11228 a         6172 c         3614 g        13224 t
ORIGIN      
        1 gctgcctttt acacagccat acaggacgat tgtattcgta aaaatccatt tgacttccag
       61 ttgaacacag tccttgaaga tgatacggaa ccaaaggaac ctctatcccc tacgcaggaa
      121 gcggcttttc tgtcctttgt gcagcatgat aaagtctatc agaaatacta cgacgagatt
      181 atcatactgt tagggacagg gcttcgcatt tcggaactct gcggactgac ggaagctgac
      241 attgacttag gcaaacagct tatcaatgta gaccaccaac ttttgaagat tgcagacgtg
      301 ggctactatg tggaaacgcc taagacgaaa agcggcaacc gggttattcc tatgagtgaa
      361 aaagtgttag aagcatttca gcgggtgctg aacaagcgga aatatgcaca gcctgttatt
      421 ttagaaggct acacaaagtt tctgttcctt aaccggaacg gtttgccaaa agtggcagtc
      481 aactatgaaa gtatgttccg ggggcttgta aggaaataca acaaaacgca aaaggtagca
      541 ttgccaaagg taatgacacc gcacacctta cgccacacat tctgcaccac gttagcaaat
      601 gcaggaatga acccaaaggc attgcagtac atcatgggac attccaacat caatatgacg
      661 ctgaactatt acgcgcatac gacttccgaa acgtcgataa cagaaatgaa gcggctgatt
      721 gcctaagtag taaacggaga atttactact ccacatacta cttttgaaca ccaaaacata
      781 cggggatata agaagatttg agagtatctt ccacaatgaa aaatgccgga aaagcctgta
      841 acaataggct ataccggcat ataagaactt ttgaaaagat aatcaaaaat tactttgtga
      901 tttaataaaa atagaatgca catattataa acttttttaa tatatatatt attagaataa
      961 gtttttgtaa acttttttat agttttctag gaggtgcaag tttaatatga gtaacaagaa
     1021 aaaaaaggat ttagatacta gttacatgcc ttacttagac ccagcgaact atgcagatta
     1081 tattactaat gaagaaattc cccaagatga attgagaaat gaccctcaaa tttctaatgg
     1141 ttatacaaaa atacctaata accagaacat aaataactta tatcctaata atgtaaatca
     1201 ttatcctaaa agtagtaatt ctccaaacaa cttgcctaac acaaataata catccggaaa
     1261 tatgaattac aatacatctg ctacaaataa tatgcctaat aacatgaata ataatacggg
     1321 tatgcctaat aatatgtcta acaatatgaa tagtaatatg ggtatgccta acaatatgtc
     1381 taataacatt aatagtaata tgggtatgcc taacaatatg cctaataata tgaatagtaa
     1441 catgggcatg cctaacaatg ttcctaataa catgaatagt aatatgggta tgcctaacaa
     1501 tatatctaat aatatgaata gtaatatggg tatgcctaac aatatgtctg gcaatatgaa
     1561 taacaatatg tatggtaata caggtatgcc taataacatg aacagtaata tggggtataa
     1621 tatgaacaat actatgggta ttcctaactt ctcatgtaat caaaatatgc ctcctaatgt
     1681 acttatgatg ataccaggag ttatatgtca taatacaatg caaggtatgc ctgtagttat
     1741 gcctagtact atgcctccta atatatatcc tactccttat ggttctagta atatgtctat
     1801 acaaggtata ccacaggcta ctaatattga agaatttgat gaggaagaaa tgtaatatat
     1861 atttttttaa gtaagttgta taaaacatta ataattgacc ataataataa atgtattcct
     1921 cataatattc ccccaatatt attataggta tagaaagttg actgaatatg cgcttattcg
     1981 gtcaacagat attaacataa tctaataaga taaacataga aaaagtcaga taaaatttaa
     2041 ttttatctga ctttttcatt taaaaatgct ctcttgtgtt ggtgattcag aatagtatga
     2101 tactcgtatt tgagactaat attggcaaac aacataaaga aaaatataaa ttttttataa
     2161 taaactgtat aaaattttaa taattgacca caataataaa tgtattcctc ataatattcc
     2221 cccaatatta tagaaataaa tttaagcgag attaaattca gttaatctcg cttaaataat
     2281 gtctaaattt attattccaa aaaatcatca aaatctaatg aacctgattc tgcaaaatca
     2341 tataatgcat tttgctcaaa gaaaaatttc tcttcaaatt taatatagtc gctataatta
     2401 gattgactta tttcattgat ataattgcaa tcattttcgt tataagtacc aataaaaaac
     2461 ttatttccca ttaagtaata tatagctttc atatcattat ttattatata tacattttct
     2521 tttacatggt cattattaaa attaaatcta gtaaagaata taccttcatt catattactt
     2581 tttaacagaa atggattttc tctataaaat actcctgcaa attcttcagg tgaatttaca
     2641 ctgtaaacac ttacaaattc acttttagaa atctcatcaa atacctcaaa atcatacata
     2701 ggttctttat ctgtcactaa tagagaatta attctaaaac cagtttcata acacttactt
     2761 atgcaaaaag caattttaca tatataatat ccatcattat cttcatataa agcttcactt
     2821 atatatctgc cttgaccttt atcacttacc acgtttttaa gtaatgttcc atttatatta
     2881 gtaatgtgca tatttgcaat ctcgtcactt ccagaaaagt actttaaact ttctctatcc
     2941 catgctataa atctcatggt catatagttt ataaattcaa cttcctcgtc aactctttta
     3001 catattttat tgtataattt ttctatagtt aaatctgttt tatagttttt tataatatca
     3061 atatactcac atttatctcc tggcaatagc ttatcataat aaagattctt attaccaaaa
     3121 taagatacta aaaataaaga ttcatccttc gttaattcaa ctctatctga accaaatcct
     3181 cccatcaatc tttcttcttc catataagct tcttcttgtg ttgggttatt taaactcaca
     3241 taatccgcta atcctaatcc ctctgcatct aataaaaaat attgacaaaa gtgattgttt
     3301 tcatcatcta tccaatttat tataagacct aaactgccca taagtctaga atttgtagcc
     3361 tttgcaaaat taaaattcat atagtcacat cctttaaact ctaaaatact tgttttttaa
     3421 tatataaatt attatacata tattttaaca acttagatac aatttataat ataatataag
     3481 gaaatgatta attgaggtgg tcttatgaaa aatatagcag ctttttttga tatagatggt
     3541 actctttata gagactctct tatggttgaa cattttaaaa aattaattaa atacgatata
     3601 attgaccaaa aaaattggta taaacatgct agagacactt ttatggattg ggataaaaga
     3661 caaggtaatt atgatgatta tctattagaa atatgtgacc tttatgttga ttcactaaaa
     3721 ggattagata aaacctgtat caactttaca agtgaccaag taattaaatt aaaagcagat
     3781 agagtttata aatacacacg ttcaaggatt gagtggcatc taaatcaagg acacatagtt
     3841 atatttatat ctggtagccc tggatttctt gttgaaaaaa tggccaaaaa atataatgta
     3901 accgattttc taggaagtga ttatgtcttt gaaaacaata tatttacagg cacagttatt
     3961 ccaatgtggg attctataag taagaataat gctataaacg attttgttgt aaagtatgat
     4021 ttagatttat caaactcgta tgcctatgga gatactaatg gtgatataaa tatgctaaaa
     4081 agagttggaa atccaatagc aataaatcca acaaaggaac ttttatctca aatatcactt
     4141 gatgaggaaa tttctaaaaa tgttgagata atagtagaaa gaaaagatat tatttattct
     4201 ctatctacag atgtaaatat agtggatatt taatttatac tatctatttt aaaaacttat
     4261 attatatcta atatttatat ctaacatata aaagctttga ctaaaaatca aagcttttat
     4321 atgttgcact aagaatatat taaatttagc tttatgcttt aatgtatatt catatatatc
     4381 atttacactt atctaaacta caatttcatt aaaattaaat ataaaaatca actattattt
     4441 tttaaatagc atctttctta acctattatt gtaataacct ataaaagaac tgtaaacata
     4501 gtcatatact ataaaggcta tctcaaatga acctataata aatatgttta ttggaatata
     4561 aactattgtt cttaataaaa aatacaatat aagtatcatt atatttgcaa atactaattt
     4621 cataaaatac tcaatatata tagacctatc tttttctata agatatttta caataccata
     4681 tattccaaag gtaagtgaat atacaatcca ttgagactta cttgccatca ctataaatcc
     4741 taaaactata gaacctatat aaaaagcgat tccactctta aagccccatt ccattattac
     4801 aattgatact aaaagtgatg ctaaccccat aataaacaat gtatttacag gaataatatt
     4861 tgtaagagtc aacaatatca catttaatgc taataaaact cctccataag caacttttat
     4921 actcatattt atcatcctaa caacaagtta ttaaatctcc accaaaacat tcacaacatg
     4981 aatctaaaca ccaaagctta gcacaatttt cacaacaatc gtcacctaga caacaacagc
     5041 aatcatcaca gcaacagcaa caacatccat ctaaatcatt acgtcttctt ctattataat
     5101 tgtcagccct attgctataa tcatttctat attgtgtata acttctaagt gcatcactat
     5161 attcactatt ttcaggctcc ataaattttg ctctttttaa gaagtcttca ccttcttcat
     5221 aatatcctat gttcattgca gaaaagccag ttaaataata ccactctgca catttgtcag
     5281 tcaaagtttt taaaaaatca tatgcttttt taaattcact attttctatg aatgatcttg
     5341 ctctcataaa attttcatta ttataagtat tactgtacat tctttccacc tctactttct
     5401 aatatattaa tatatcttaa ataaacacca gaataaatta tattttctat tattccaaca
     5461 tttttattta gatttagatt atcaattccc ctagctaaaa aacctaatga tgttactatt
     5521 atttttttta ctttttcttt taactcatca tttttatcaa tatactctat aaatggatta
     5581 tatcttcctt tcttaaaatc ttcatctaaa tcttcatagg catctagtag atatatatac
     5641 ttacctatat taaaacctat cattcttaag tttctctcat tttcatcttt tttatagaca
     5701 aatacttcac ccattatatt tccaaatata ctagatactt catctatatt tatattttta
     5761 tctttttcta acttatttaa ttcatttagt tgttgtttta tatactctgc tttttcagga
     5821 tacttttcat atgctaattt taatttgttt ttatatatat aatatgccaa tttatctttt
     5881 atgcgtttat catccattaa attatcttcc aatttataat acgttaaaag aatattcata
     5941 cttgctgcat attctgtaat atcatttgta attacctttt tctttttaaa tggatttact
     6001 atacacactt cctctgtact tatagactct gggttatata ctgctgttaa taaaacaatt
     6061 aaaaatgtta tatcataatt caaagaaaac ctagagattt ctccatgatt tctttttaag
     6121 tatttacata gtccacaata gtaagctttg taataatcat attctctaaa tgttaaatcc
     6181 attttgttta ttttaacata tccaaacata aatactcctt tttgtactac tttattatat
     6241 aaattatatt tattttctaa ctcatttatt ttatagtgca ttatgtaagt ttttactctt
     6301 tttacttact gatgctatat agtccttttg acttactaca tattatctct aagttactta
     6361 tatcatttaa tagtatattc tttgcctttg aacaagtcat tttttatccc ttattattta
     6421 aggttcaatc aagatttaac aagctatata tttacatttt ttgtaagtct aacataatta
     6481 atatattaaa aagatgtatt tatcctatat gtttatgtgt taattagact ttagtaacct
     6541 taattgaatc tattgtttca ttggttagaa aatgagtgta tgccatcaaa cattaactcg
     6601 ctcctctttt attttttgtt aattattatt atatcattaa taaaattata attcatttat
     6661 tttatatgta atcattaata aattcttatc tacttctctt ttctttttta agtcttctat
     6721 attcgtctaa gaatgttctg ttaggtatag ttacttaatt acaatctcat ctattgttat
     6781 acttacatct ttattttgct ataagctatc atttattacc tatttcttct tattttttct
     6841 attttagtgg acatttaatt tatgacaaat aaatatattt atttgattat atttaataca
     6901 aaactattct tataaccttt ttaaatcata tttaacatat aatattaagt aacatactta
     6961 cttaagagga attattaaat gataaaattt gaaaagttaa atattattaa caataaagat
     7021 atgaaagaaa tactagatac atgggaatca tcagtaagag caacacatga ctttttaagt
     7081 gaagaaaaaa taatatcaat aaagcctcaa gttaaagaag gtgctaaata tgttagtaat
     7141 tttttatgtg taagagacaa aaaaggtctt ataaaagctt ttatgggaat acatgatttt
     7201 aaaattgaaa tgttatttgt aggtaattat agtataggaa atggaattgg aaaaagactt
     7261 gcagaatatg caatagaagt attaaatgta aattatgtag atgtgaatga gcaaaatcaa
     7321 caagcattag gcttttataa acatatggga tttaaagtct ttaaaaaatc tgagttcgat
     7381 gaacaaggta atccattccc tatactgcat atgaaattaa aataacaata taaactatag
     7441 tataactaaa taaatataaa tagagtaata attgaaaaat attactctat tatcataacc
     7501 ttactctcac ttatcttgtt ataataatta tataatatat ttttaggtcg tttaaactgt
     7561 atttttagtt tttaaataac aaatattttc tattgttgat ttccaatgat tttatacaaa
     7621 aatagtataa ttgttatatg ttactataga agttttattt atttttctta ctgtctaata
     7681 ctactccaat aactaatcca aaggataaac caatagctaa gtttttaaat aatgaaccca
     7741 aaataacacc aaaacataat cctaacgcca aataacttat attttcattt ttcatatatt
     7801 actcctttaa atttaattgt aacattttaa cttttctaat tgattctttt gaagttttga
     7861 ctatatcaac taaacctctt atctcatagt tattacactc acttagcact ccttttacta
     7921 atattttaag atatctcccc taatttataa acagtagtag taaaaaatgg tttttaaaca
     7981 tatattttca aagtctaata tatataaaac tatttttatg aatctttact aattccaact
     8041 gctcttaaag gaccgagtaa cgacattcta acaagtatca gtaccatttc ttcagggtaa
     8101 tctataacct aactaaacct aaaaaataaa attaattata aacaaaaaat aaatataata
     8161 aaagggctta caaattataa gtccttttat cgaacataaa atcaaattat tttccttaaa
     8221 taggaaactt taaaaatata ttctaattat tatatcttag attgaaaata attagaaagt
     8281 taagttaaaa ataatgttaa tttatatatt tatcctaatt catacaattc aatcttactt
     8341 gtattaaatt actcttcaaa taattggagt atattcaaaa ctacctacag tatacttcaa
     8401 ttcttttttt gctttattta taaccaattc atcaagcatt acatcattta ttgaacatga
     8461 tatagattta gatgccaata acattgcttt aaatcccata tcagaacctg cacttgcaca
     8521 agattgccat gtatgggcag aaataccaat aggccaaact gaacaagaac actgtgctgt
     8581 aggaattatg taactaacat ctccaatatc caatgataat gatatacagt tattatgagt
     8641 aaatgtatca tccgtaactt catcatgtaa attcatctta gtaatatcct tatttccact
     8701 taagacacta gaaacactac ttcttttatc tatagacact gtctcagcta atttatctgc
     8761 aaaatagtag tcatcttcat tatagttttg tacacctact aatttcatat tttgtgatag
     8821 aatatctgtt aatattgtat ttggaatata gtcatatact ccacttataa tatcatattc
     8881 catactagta ccagtcatta atgctgctcc ttttgctata tcaacaatcc taccaaatac
     8941 atctcttaca tgctccattt taactcctct tatgtaatac cacacttctg caaaatctgg
     9001 aactatattt ggcatttttc caccattagt agttacatag tgtactctac aactatcaaa
     9061 tatatgttct ctcaaataat tacaacctat attcataagt tctactgcat caagtgcact
     9121 tcttccgtta taaggagctt gtgctgcatg agcactaatc ccattatatc taaatttcac
     9181 agagtaatta gcaagtgttg ggattcttat aggagtattt atatcaaatg gatgccaact
     9241 aaaagcacaa tcaattccat caaaaaaacc tttttttatc atcaatactt ttccagataa
     9301 atcttcctct gctggacatc catagtattt tatagtccct ttcagctttt ttagtttgat
     9361 taattccttt actgcaatta cagctcctat tgaacctgta cccagtaagt tatgtccaca
     9421 tccatgacct gcaccaccat ctacaatagg ttctttaata gtggatactt tttgagacaa
     9481 accatctaaa gcatcatatt ctcccaaaac tgctataact ggtctacctt ctccatagct
     9541 agccgcaaat gctgtatcca taccttctaa ttcatctata ctaaaaccat atttttttaa
     9601 gtattctttt tgtaaatttg aagcataata ttctttatac tgaagttctg gatttttcca
     9661 tatcttatct gatatatctc ttaattctcc ctgtatctca tctatatatt ccatcaaaaa
     9721 ctttttattt aaattctcca tattaattat ataaacctcc ctgtttctaa taacttatcg
     9781 attatcagcc aaaatgacta attttaactg atttaaaaat attttctacc atacaaccat
     9841 tttatacaat aaaacctctt gacttgtaag tttcatttta tcaagtaaga ggttttcaag
     9901 ttttataaaa tttttagcat gttaaccaat caagcatatt aacccataat ttattatagt
     9961 atttccaatc agtaaattct tttggacccc agtgaggtgc acagtcagaa ctaaagatag
    10021 cagattttcc ttttccaaac tcgccaacag ctacaaatgg gtctcctcca atagttgcta
    10081 aaacaggaca attatctcta gctactgttt tgttatatcc taaaaacttt ggccattctg
    10141 ttggtatacc ttttaatact ggatgttcag agtcaataac ttctggaatt attcctgctg
    10201 gtttttcaac tctatcatct ttatctatca ttgttattgg taatacatct ttgatagcag
    10261 tttctccaaa tctagctttt gcatctattc ctgtaaatga catatatcca cctaccatga
    10321 ttaacgcccc accattattt acatactctt tgattagttc aagtctatct ggattactat
    10381 tgcaatctat aaaagtacta ttagataata agaacgtatt agaacctata tcagataata
    10441 ttatacagtc atactcattt aactcttcta atttatacgg aaaactatct gctgctacat
    10501 gtgcaggcat atgaactgtc tcatatcctc cagattctat tgcttctttc aaccacttta
    10561 cagcttcttc ataatgagtt gtaacaaacg tatcaaaccc ttttatatga gttatatttt
    10621 ttacccaaga ttcccctact attaatactt ttttcattta tatattcctc ctacttttat
    10681 aagtttaata ttagacttgc atacataagt atactatcta aatactcctt aatttcaaca
    10741 tattcatcaa ttgaatgaca ttgttctatt gaacctggcc ctaatataag tgttggtatt
    10801 tcagctaaat ttttcattaa tctcgcatca ttgccagctg ttgaaccttt tatctctaat
    10861 ttttttccta gagtttcttc tagtatttta tgtgcattca ctacaaaatc agaatccttg
    10921 tccatctcaa aacctaaccc tgattgatat atgtttatat ttggtttatt atctttaagc
    10981 cataaatctc cattagccct tgtcattatg acatttgtta catcatttac aacttgttca
    11041 taactcatta tatttggcaa gaagtgtaca cataaattaa atacacactt atctggcaca
    11101 gtagaacctg ctgttccacc atttattaca cctaaattta ttgtaggtga aggtaatagt
    11161 ggatgtttat atatcataag ccagttatgt tccaactctt ttatatcttg aagcaacaac
    11221 atagccttct caattgcatt tacaccctcc cacttactac cacagtgaag agacacacct
    11281 ttaacctcaa cttcaaagaa tacaaatccc atatgtgcaa ctattaagtt ttgttctgat
    11341 ggttcacaaa ttatgcaaca atctccacca ataccattca taactgcatt tatggtacca
    11401 tttccgccac cttcttcatc tactactgac attattttta cattaccagg tacatttaga
    11461 ccactatctt ttataagctt tacagctaat attgatgcta taagtccaga tttcatatca
    11521 gcagttccaa gaccataaag ttttccatta tcttctgtag cacgatatgg attatatttc
    11581 cacttactta tatcacctgg tggcatagtg tctacatgac cattaaatac aattgtctta
    11641 ccaggtaaat catcactata cttacaaatt aaattatatc tatcttgata attgtgacct
    11701 agatttcctt ctttatatat attttttgct tttttaatta attcttcgct catttcttgt
    11761 ctatctacac taaaacctat gtaatttgca agtttttcaa tatattcctg tccttctttt
    11821 tcaaatccac ctagtattcc atgaccaaca tcttcagtct ttatacttac aagttctttt
    11881 aaataatcta tgtattcttg ttttttacta tttaatgtat ctaagagaat ttttttcata
    11941 tttcctccta agatttattt ttacatttaa aatttcaagt ctaatctcat ctatttaagc
    12001 catagtaaac tttttcactt agcatattcc cattcaatgt ataaagatgt atgcaaatta
    12061 aagtataaaa atatatacaa aaacttaata atttttatag tttataaact aatatttaat
    12121 tactatttag atttagctga tttttttaat tttatattat ttatccatat agcaaataac
    12181 attaccaaac cttttataat catttgatta tatgaagata cacttaataa gtttaatcca
    12241 tttcctaata ttcctattat tccgacacct atacatgtac ctactataga accagaacca
    12301 cccatcatat tagtaccacc aagcacaacg gctgctatag catccaattc tgctccatct
    12361 ccaacagttg gtgaacctga tgccaaacgt gatgatagta ttatcccagc taatgctgtt
    12421 agtagtccag ctagtgcgta tacttttact ataactttat ttacttttac tccacataat
    12481 ctagcggcct cttcatttcc acctactgca tgtacatgac gtccaaaatt agttcttttt
    12541 aatagaaaat gtcctgctat tacaactata atcataatta taactggtat tggtattggt
    12601 ccaatatatc ctctaccgag catcttaaat gcatctgtat ttactgatat aggtcttcct
    12661 cctgtaaata caaagcttgc cccacttatt atcgttaaca tggctaaagt tacaatgaat
    12721 ggaggtagtt tttgtgttga aataattgca ccttttatga ctcctaaaat tgtccctatt
    12781 gctaatgcaa gtatcatacc tacccatata ggtgcattat aattcactac tgttgtagcc
    12841 caaaatgtac ctactaaagc aattactgct cctacactta aatctattcc tcctgtaatt
    12901 attacaaatg tcatacctac tgcaagtatt gcatttattg atatttgtct tccaacatta
    12961 attaaattat ctaaagttaa aaagttagat gaagctacac tcattattat aaaaattatt
    13021 acaagtccta cagctgcact cccttggtct ctaaatacac ttgttaattt tgtcaataat
    13081 ggagaagatt tttcttcttt atgcttagtt attgaactca ttaattttac ctccgaaagc
    13141 caattttaat acattatttt caaccatttc ttcaccttct aaaaatccac ttatatgacc
    13201 ttctctcata accattattc tgtcactcat tgatattaat tctggtattt cagaagatat
    13261 cattattata cttacaccac tctccactaa atctcccatt agattgtata tctctgcctt
    13321 agcatttaca tctatacctc tggttggttc atccataatc aatatatctg gttgtaataa
    13381 aagccatctt gctattatag ctttttgttg gtttccacca cttaaacttt gtataacttg
    13441 attcatatgt ggtgttttta tctttaaagc ttctatgtat ttttctaaaa tctctttttc
    13501 cttttttcta tctataattg atttaaactt agatatcttt tttaacccag ccatagttgt
    13561 attttctttg acactcattt gtaaaaacaa tccagtacct tttctatctt ctgttattaa
    13621 tcctagtcca ttttctattg catctgatgg agttttaaac tttacttctt cattgtttaa
    13681 atatattttt ccagaatcat atgttctaag tccaaatata gcttctacta tttcacttct
    13741 cttacttcca actagtccac ctattcccaa tatttcacct tttcttatat taaagctaat
    13801 atcattaaaa acattgttct tagttagatt ttccactcgc ataatttctt cttttatttc
    13861 tacttttctt tttgggaaaa attggtctag ctttctatct atcattaaat taactaattc
    13921 ttcctcagac gatacatctt tggtattcaa agtcgaaatc gttttcccat ctcgcattat
    13981 agttattctg tcacaaatct caaagagttc ttccatccta tgggatatat atattatact
    14041 aactccactc tcttttaaat catttataag tctaaaaagt atttcagtct cttttttact
    14101 tattgaagaa gtaggttcat ccattattaa tactttagtt tctgatgata aaactcttgc
    14161 tatttctacc atttgttttt gagctatact aagctctttg actaaactat ttggatttat
    14221 atctattccc atattatcga aaatcttttt agcctcttca ttcatttttt tgtcattggt
    14281 taagactttg ccatttattt cttttcccat aaaaatattt tgtgctactg ttaattcgtc
    14341 aaaaactgtt agttcttgat atatggcatt tatacctatc tttttagaga tatctgggga
    14401 tatattctct atttctttgc cttcaaaaat aaattttcca gaagttttcg aatgtgcccc
    14461 agttaaaatc tttatcattg ttgatttacc agcaccattt tcacccagta gtgcatgaac
    14521 ttcgccatga aataactcaa aattaacatt atctaatgct ctgacaccag gaaattcttt
    14581 agcaatatta cttaacttca gaattatatt actcataatg acactccttt ttaaatagga
    14641 tttctttcaa ataatctcat tttattttac taattcttaa agtcttttat attttcctta
    14701 tcataaagta aagctggtac tggtatattc ttttctacct tttccccttt tatagctttt
    14761 actactgctt ctacagctaa acgtcccatc tctttaggtt gttgttgaat catagcaaga
    14821 atagttccat ctgttattcc acttgatgct tcttcagtta agtcaaatcc tacaatctta
    14881 acatccttat tttttgcaga ttcaagtgca gctttagctc ctagtacact attttcagct
    14941 gttgcatata ttatatctac atctggatta gattgaatta agttttctac tgtattaaga
    15001 gattcttctc tgtcatatcc tggttgtgaa tttaatatct taacatttgc tgaacctttt
    15061 aatgcatctt taaatccatc tattctctgc atttgtattt gagattttaa atctgtcact
    15121 attgctattt ctgactttcc acctaacttt tcatctatgt attttttagt gtattcccct
    15181 aattttttac cagcatcata actaactgtt cctacataac ttgtaatatt ttcagtattt
    15241 aatacagcat ctactgtaac tactggcatt ttttcaaatg ctccttctac tgctggtact
    15301 atagccgaat tatcagttcc aagtactatc attccatcta cattctgttg tataaaatct
    15361 tctattgctg atgtttgctt agctacatct tggtctgggt catttactat aactttcaca
    15421 cctaattctt tagctttttc ttttattccc tcatcaatat ctataaaaaa ttgatgttga
    15481 agagttattg tagatactcc aatagttaaa tctttcttgt ctgaaccacc tttattatct
    15541 gatttacttg gtccttccat tgaacaccct gttaacattc ctattgctag tattccagca
    15601 attcctaaag ataaaatttt tctcactctc ataattaacc tccattttta atagttttaa
    15661 atttgaacaa attagatttt tatttattat ttaaatactt ttcaacatct tctttatagg
    15721 gcataccaga ttgtgcacct agtttagtta cagaaagacc tgatactact actgcatatt
    15781 ctactgctgt atataaattt ttcccttctg ttatagccac tgccaatgct ccattaaatg
    15841 tatctcctgc tcctgtggta tcttgaacat caacacttat acaagataca tgcttgattt
    15901 cctcaccatc ataaaatcta gctccatttt ttccttctgt tattacaagt ttatttggat
    15961 atttttttaa tacttcttct atcccttcat ttgtgtcaaa aactatctta tattcatgtt
    16021 catttggtgt taagtaagtt actttttcta ttatatcttc atttagtttt actgctggtg
    16081 ctggatttaa taaaacccta atcctatttt caaaacagaa attcactaca taatttattg
    16141 tttttaatgg aatctctaat tgtagcaata ctatatctgc attctttatc tcttcttcat
    16201 tctttttaat taattctata tctactagct cattagtccc tggtacaaca acaatactat
    16261 tatcattttc acataatgtt ataacagcaa caccagaact tttgtgatta tttctggata
    16321 ctaagctata atcaacttta ttcgttctaa aatttcttat taactcctct cctaagccat
    16381 cttcccctat gcatgatatc atttttacat ttgctcctag tttagaagct gagatagctt
    16441 gattagcccc ttttcctcca ggtgatgtaa aaaaactatt acctaatact gtttctcctt
    16501 tttctggtct tttatctaca gaacatacca tgtccatgtt tacacttcct atgacaacta
    16561 tgtttcccat tacattactc ctttacatat ctatttatgt ctctcgtgct gttattcact
    16621 ttcttttgtt gaatctctta tgaccaattc tggtttgaaa atcaattcat caaacgattc
    16681 ttttttatct cctcttaaac aatttatcaa tatttcactg gctttatatc ctatatcata
    16741 agacggctgt tttactgtgg taagagaagg gcttattaga cttgatgttt gaatatcatc
    16801 aaatcccacg acacttatat catttggtat acttaatcct ctttctttaa gacctcttat
    16861 gacacctatt gcaatcaaat catttgcaca aaatattgca tcaaaatcta tcttttctaa
    16921 attttttata aattcttgtc cccattcaat cttatatttt ccttcaaata cataagcagg
    16981 attgtagctt aaattacact cgattagagc ctttttatat ccttctaatc tatctactgc
    17041 tatttcattt tgaagtggac cacttaggta tattattttc ttatttccaa tatctaataa
    17101 atgttttgta gctatatagg ccccttcaaa gttatttatt ttaacaattc cttttaaggt
    17161 ttctttgttc atacttatct tcttatcaat caagacagtt ggtattttta tatctttata
    17221 atttgcttct ttccagtttg tatttgaaga tgctgcaaat ataattccat ctatcatcct
    17281 ctctgatagt gttcttattc cttcatattc ttttttagca tcttcatctg tattacataa
    17341 aattatattg taaccttctt cattagcttt gtcttctaca cctcttgata catctgtaaa
    17401 gaatggattt cgtatatctg gtataagaag ccctatagta ttagtttttt tagttactaa
    17461 actttgtgct aatttatttg gtacataatt tttttccttc attattttca aaattttttc
    17521 tcttgttgcc tgacttatat tttcatcttt attattaatg acttttgaca cagttgtttt
    17581 agaaacacca gccaattcgc caatttcttt tatagttata ctcaagaagt tcacccccaa
    17641 aatttaggaa accgttttac ttaaccggtt acctagatac tatcacatct tttttccatt
    17701 tgcaaccatt ttatataaat tttgatattt ttcccttttt tcaaaatatt gcaacttata
    17761 attcaatttt aatatttaaa ttaatctgca aaaaaaaatt aatatacttt tataattatc
    17821 taaaagtata ttaattaatt taagcagtat ttattaaagt tcaaatcctt gctctataat
    17881 cattttttta tcattttcaa tcccacttcc aacagttgtc aaataatcac caacaattgc
    17941 agaatttact cccccattaa atccaacttt gtcatatccc tttaatgata gccttccacc
    18001 agcatacctt atgtacacat taggaattat aaacctaaat actgctgttg tttttagtat
    18061 ttccattggt tctaatacat cataattttc cattggtgta ttcttaatag gatttaaaat
    18121 gtttattgga aatgatttta catttaattc tcgtatttca aaagccattt ttagtctctg
    18181 ttcttcactc tcattcattc caattatacc acctacacat acatctagcc cagctttttt
    18241 agcatctttt atagttttta tcctatcttt atatgtgtgt gttgtacata tattatgaaa
    18301 attatctcta cacgtctcaa cattgtggtg atatgtagtc acacctgctg acttcaacat
    18361 tttagcttgc tcataatcta taatacctaa agatgcacat aattttaaat tagtattttc
    18421 cctcaatcct tcatagatat ttaaaatatt attaaactcc tttcctgaca tacctttacc
    18481 acttgtaacc aatgagaatc tatgcactcc tttactctcc atctctttag ctctatttaa
    18541 gatttcattg taatctaata atgaatattc ttctacacca gttttataat gagatgattg
    18601 agcacaaaat ttacagtctt cactacattt gccagattta gcattcatta tcgtacataa
    18661 atctgctttt cttcccataa aatattctct tatttcattt gcagatttta atagaatatc
    18721 aaaatcgttt ttattatttg tatcaaggct tattaaatta agagcttctt cataacttat
    18781 ttctttttct ctcaatactt tattttttaa ttttattatg tatttttcca tatatcctcc
    18841 tatttgtcaa cttaatattt ttatgtagtt tacttattat atatagtatt gcatatataa
    18901 catttattgg tcaactttat tttagacaca agtttactat acacaaaaaa atactgcttc
    18961 aaaataatat tagtaaatgg attatacata ttattattaa aacagtattt tttattagaa
    19021 tataattctt actggtttat aaaactatcc ttgtcttaac tccatccaag ctttccattg
    19081 taataacctc taagccttca tattctctaa atagccattt taaatccttc atggcttgat
    19141 taacctgact ttttgttaga ttatttataa aatattcttt tctagtttcc tcatactctt
    19201 tgctagtcaa aaagtttctt agaaaattaa acgcaaatac acttggaata ttgtttacat
    19261 tagccttctt gctgttttcc ttctcatagt aaattttcat aaatgcatac tcctttgata
    19321 cttttagatt tctcttacaa taattatatg catttaagtg ctactattct tataatttta
    19381 ttaattcata ttctttactt cccataccca tttcacatgc atagtctatt attctagttc
    19441 catttacatg aggatgttca tgtttgaaaa catcatgacc catttcctta caaatcaaat
    19501 catagcatgc ttgttcaata gctacagggt ctgttgatgc taatattcct atatcatggg
    19561 caattggtct acctgaccaa ggtacacaat cacaaagtgg agttacattc ataacaaaag
    19621 ttatataccc taccttgtct tttttatttg atactgctcc ataagcgtat tctgccatct
    19681 tttcgacaaa cacatctgag tcactttccc attgtatagt tactgctcta gttggacaga
    19741 cagttggaca ttctccacat ccataacata catcagaatc tataactgct tttttatcca
    19801 ctatacttat agcttttgta ggacaagaat taacacactt tccacaacct acacacttct
    19861 tttcctttac tactggagta acatcagaat gttgcatttg ttttcctgct gcacttgcac
    19921 atcccatagc taagtttttt aatgctcctc caaaacctgc tgcttcatga cctttaaaat
    19981 gactcattac tatcattgca gaagaattat aaatttctcc acctattttt acactttcaa
    20041 aatgtttttt gtctattttt acattctcat aatttctact atataatcca tctgcaatta
    20101 ttactggtgc atttacaact gcataagcaa atccattttc tatagcagtt gtaagatggt
    20161 ctacagaatt tgttctactc cctgtataca gtgtatttgt atctgttaaa aatggctttc
    20221 cttcgcagtc tttaacctta tcaaccactt gtctaactgc cacaggactc atatatgtag
    20281 tatttccctt ttctccaaag tgaagtttaa ttgcaacttg gtcattcttt tctattaaat
    20341 ctttgaatcc tgcttcatca aataatcttc ttacattgtt tggtacgttt ttattttgcg
    20401 aatttgagta taaatcacaa aaatatactt ttgacttttc catatctaca cccctttaaa
    20461 atatttactt atactaattt tatcactttt aaagtaattt ttagtatatt ttaacataat
    20521 taaatattct tatatttatt tgatacaaat aatattattt gtattatttt ctacacttaa
    20581 ttctatatat taaaaatcaa aaagacttga aacttaagtc caagtctttt tgatttttag
    20641 gtgtagtttt taacaacata agattacttt accttgtgat aaaggtatta ttaaactggt
    20701 tttttattaa ataaaataac agctgctagt aaacatacta cagaaataag aactgttata
    20761 ataattggaa taataaattc tggcattgcc actttccctg aaatcaagtc tatatttttt
    20821 gacatcaaga aattaggagt ataaggtgca atctgtttag gaatagaaat taaactcaat
    20881 aaaagagttg ccaccaatac aagtaaaaca ctggcaaatg ctggtctaaa tagtacacac
    20941 ccaagaatta atacactaat atacataatt cctataagcc ataaattaaa tgctgaaaat
    21001 ataatatgat taagatttgc agttggccaa aaatatattg tatagccata agcaaataaa
    21061 aaactcaacc aaaaaccaat tgtcataata atcaccgtaa cagagaattt agacaatact
    21121 atagatgaac gtgataaacc tttagtcagc ataataacaa gtgtcccttt agaatattca
    21181 tttgataaaa tattacaaaa aataattaga gttaaactca taccaagacc agagatattg
    21241 ctaaaaaatt gtgtccaaga atctaaagca gttggtgcag cagtaacttt taaagtcggt
    21301 gcaaaatgag caatcaagtc tggcataaat tttgcagaaa taggactact tataccaaat
    21361 attagaaata aaataattaa actaaataat ttataatttc ttaaattctc tttaaattct
    21421 ttttttgtaa atgctatgta ttctctcact ttactacctc caaaaataaa ttttcaagtg
    21481 ataattctat tagttccatc tttactggac aaagattcat ttctgcgagt gtagatataa
    21541 ctgttttttg tattgctttt atatctttac catgcaaaac aatttccata ttagtttctt
    21601 ctgaatcttt tagtaaggat ttaataccat cactagactt aaacttttga atttcatcat
    21661 tacttgcaaa ctccagtaaa agtctatcct ttccgtgcat actttttatt tctgaaagtg
    21721 taccactaag ggcaatgctt cctttgttta atatagcaac atggtcacag attctttcaa
    21781 catctgatag tatatgtgtt gaaaatatta cagttgttga gtctttgatt ttaagcataa
    21841 tatctaatat ttcttttcga ccaacagggt caagtgcact tgttggttca tcacaaataa
    21901 gtaatttggg gcgtgaaagc aaagcttgag ctataccaag tcgttgcttc attccacgag
    21961 aaaacccacc tattcgtctc ttttcatttc caagacccac aagtgataac aactcttcac
    22021 tccttatctg tatttctttt tttgaaagtc ccgtaatttc accacaaaga gaaagatatt
    22081 caagtggtct catatagttg taaaactctg gaacatcagg cagataacct acatgacgat
    22141 tagaacttgt tttcccatag gtcactttct caccacaaac atctatagtt ccactatctg
    22201 gtttaagtaa cccaagtacc attttcattg ttgtagtctt acctgcacca ttcttaccta
    22261 caaacccaaa gactgaccct tctggtacag taaaatttaa attatctatt atctttcgat
    22321 taccaaaacc ttttgataat ccatttattg agacaatatt catcattctt cacctcttcc
    22381 tattgtaaaa tacaaaattg gtcctattag actaataaac agtactacaa taatccatat
    22441 tgccttattt ccaattttat aatttggatg tctcaataca tgaacaagtg cagtaattat
    22501 aagtattaaa tctaaaataa taacaggaac caaaagtggt aagtattcca tcaaattttc
    22561 cataatctta ttcctccaat aaagataatt tttctataag aaatttgtat tctttgtttt
    22621 cacttaatac agaaaacatt ggattatttt taatagcagc aacaatacct gcttttacga
    22681 ttgtatcatc acgtgtaata cctgttccaa tttcagaaat ccatctgtca agtttattaa
    22741 aaaagtcatc cccatgtatt ataattgggt atatatcacg tgttgctaaa tctacatatt
    22801 ttcgtaatga tttaatagct ccttcattat caccatgtat taaattaatt tgtgcctgtg
    22861 ttaaatatga agaaagcata atagcaggag ataatgtatc aagctcaaat atatctgaaa
    22921 ttgctagaat acgtctttct atttccttca tttgtaattt atctgcattt tgcaaaatac
    22981 ccactaggtt ttggactaat gatataaggt tctgatatgc accaagttga aatgtttctc
    23041 tcgcttcatc catttgacca ttcatcattt gcccctgtgc aagaagtata gattcattta
    23101 tcatgggaaa attgctgttt tgcaataaat caatcacttg tatgggttga tttaacaata
    23161 tataacaagt tgcctccata ctttttgctt gacggcaaat atctatgtca ttacaagttt
    23221 cctgtatacg aataaatatt tctaatgctt cactaattaa tagttcacgc tttttttcat
    23281 ctacaatatc atagtgatta actattaaaa gacccatccg aaaaatcaaa ggaaaacatg
    23341 aataatattt ttttatgatt tctcttattt catccatgac ttcatcaaat ggtttaaccg
    23401 taaagtcttt gcacagttta ttatacagtt tattaatatc ttccttcatc atttgaggtt
    23461 cataacatat taactcatca acggtaatgt tgaaatatgt cgcgagttgc ggtaaaaagg
    23521 ttatgtcagg atagctttgt ccagtttccc atttagatac agaagcttta gaaacgccta
    23581 tataatttgc aagttcatct tgtgtaattc ctttttcttt acgctttaaa atcagcgttt
    23641 ttgcgatgtt taattcattc atgtcaatcc ctccttatgt ataattatat ccttaaacat
    23701 gtaaagctaa caagcgattt gaagttgact tttgacgaaa aaatcaacca cagagaaaca
    23761 aataaacaag tatataaaat atatatttaa atttatcttt aatctccttt gtaaaatatg
    23821 taaactttgt aaataaaatc catattatat aaaactaata gttaatctat ctaaatacag
    23881 tttttattta tcacgttttt aaatattttg tgtaaaacct cttttaatat aaacacctta
    23941 ttttcatttc tcatttcata ttctttttaa aatactgaat ataactcttc gattttccat
    24001 ttaatccttt tataaagtta ttattcgtat ttattcctct aattataaca ggcaactatc
    24061 atgtattggt atttgtctat tatataaaaa tctataaaag aaaagcagtc aatcatttag
    24121 attaactgct tgtacatata tcttattaaa ctgtataaac tataattttt attattctcc
    24181 attttcatcc caagtcataa atccccatcc actatctgga taaatatcga tagacttttc
    24241 tctaatcata taaccaactt tataacactc ttttgttatt ttattagata gtatacatcc
    24301 ttctccattt atctaattcc atttaattaa cttttctttt caaccttaac ttttataaaa
    24361 tcatcttttt taataatttc atacttattt tctcttcaac atcatcaaat gagggtgtct
    24421 caaaattaac tttttacttc ataaggcact cttttttgta tgaagtaaaa tatattttca
    24481 tcatttcaac aataagtaag aggcttatct ctattttgag acagccccat ttgatggtgt
    24541 tgaacattta aataaggttg aactcgtttt atctctcttt ttaagatatc tgtaaatttg
    24601 cacataaagt ctcttcttct tttacaattc taatagtttt attaaagcca aagtgtatat
    24661 ctccatattc tttcgtatat gatttattgg tactctttca tctactccat gaccaccagt
    24721 tttatacgct aagaacttag gtccaaacgc caccatatct ttaaaccaac ttgcatatgt
    24781 gccaccaccc atagcaattg tatatccatt ttcatctgtt acttcttcat aggcttctaa
    24841 taatttttta agtactaaat tactctcatc cacataatgt aagtctttat gagcaataac
    24901 ctctattttc caaccattac aaaaaacctt tttgaatcta tctattatat tgtttaaaac
    24961 tatattttta ccatacctta tatctaactc acatacgatt ttttcctcat ttacttttaa
    25021 tattcctaaa tttaaggtag tgtttttgaa tacctcatca tattgattaa tccccaatgc
    25081 atctccataa taatcactac aaaggtattt tgaaactaat tctatatctt ctctatgctg
    25141 aaaatccata ttatcctcaa ctatctttat taccatttta gatatagcat tttctccctt
    25201 ttcaggatta cttgcatgta cagctactcc tttagtagtt aactctgaaa taattccatt
    25261 aataattttt gcagtacaat gagatggaac aacattttct ttagttcctc cacttactat
    25321 tatgtaaggt ttacttttgt caattttaat ttctttttct atccttatat gaacccttcc
    25381 tttttctcca ttaaccactg gatacatagc atctggagta aatcccatac ttggaatttc
    25441 ttcaccttta tctaagtaat atttgataca tttcatacct gtctcctcat ttgtaccaaa
    25501 aattaatctt attcttttat taattgtagg atacatatcc tctatgtttt tcaatacatg
    25561 tataagcata gatacagcac ccttattatc tatgacacct cttccataaa taatattgtc
    25621 aattactgct cccgaaaatg ggtctacact ccacccctct cctggtggaa ctatatctaa
    25681 atgcattgga atccctatta attcctctcc ctctccaatt tctgcatatc caatataatt
    25741 atcaatattt ttaacactaa aacctaaact agcacagtaa tctaaagttt tatctaaaga
    25801 ttttttaggt cctataccaa aaggacattg tgaaataggt tcaccttgtt gtgaatcaat
    25861 ttttatcaat tcttttagaa attctatggt tctatttaaa ctattatcta cacttctgct
    25921 tatatccata aatcaaccta ctttctatct ttttaaagcc tgtccttgaa gaacaggctt
    25981 ttagcattaa aaattatttt tttgtaaata ctaattcaca aacttcatca tcatgagcac
    26041 atttttgagc aaaatctaat ttaacacctt gtgcacagtc aactcttcca taatccccat
    26101 aacaagctaa tctacaaatt tcttttcttt cttctttagt taatccatat tctttccaag
    26161 cagcatctaa tggacagtga tggaatttta aaacgccatt ctcatctgta ttttctacta
    26221 attccatttc aaacactttt tgtcctttac tgttatataa catttctgcc atttttcctg
    26281 gagtatctgc tacgttatat ttttgacctc tcattttacc aaatccatat attgcttctt
    26341 tacatatatc atctggatta gctcctaatt tttcagcttc tttcataaga agatagaacc
    26401 atactgctct ttctcctgtt gctcctctaa ttccttctaa atattccttt tctgtataca
    26461 ttttttctga catttctttc tcctcctaaa attaaattct atattttaat cactgtgaat
    26521 tagaatattc caatgaatga ccctaccaat gctaatacaa ctaaaattac taataactta
    26581 gttattgtcc acttcttgta tttcattccc caatatacga agaatacaac accaagtggt
    26641 aataaacctg gagcaatcat atttaatgta tcttgaacaa caattgcttt accaccaata
    26701 tcaaatgata gcggagttga aagcttaact gtagttgcag ataatgctcc catcataaac
    26761 attcctagaa ttgaagcacc atcaattatc ttattgacaa taccacctga tagaattttc
    26821 ttaattgaat ctctacctaa agaatatcct aaatgaaata agtaataacc ttcgcaaaat
    26881 agtaatatac taaacattat tgggaaaagt gcacctataa cacttccttc tgctccaaat
    26941 gaagcaccta aagctaagaa tattgtttga aatgtaccaa aatctaaagt atctccaatt
    27001 ccagccaaag gtcccataag accattctta acacctgaaa taacttctcc tgggattttt
    27061 ccttcagtag ctttctcttc ttccatagct aaaactgtac cgtgaattaa tcctccccat
    27121 atagcttgag tattaaaaaa ttgtaagtgt ctctttaacg catctactaa atcttctttt
    27181 ctcttatata acttttctaa agccggagtg aaacttgcac aaactgctaa tgcttgcatt
    27241 ctttcaaaag agttggataa ttctgctgtc caccaccatc ttagatatgt ttttgttaca
    27301 tctttctttg taagtactct tgtcttatta acttcagttg gaccttgtcc atttttaact
    27361 tctttatttt ttatttcttg cattatactt cacctaccct tttgtcttct ttcataaagg
    27421 taattaaaag agctatacaa acaccaaata ttgcagctgc agtaattgat atttcaaaat
    27481 attgaaccat aaaaaatcct ataataaaca ttggtaagaa tttattttta cctatagtaa
    27541 atattgttgt tgcaaaacct aatgcaggca atataccgcc cattactgtt aatccattca
    27601 ttaaccattg tggtataaca tctaataatg attgaactaa atctgctcca aaaaagttac
    27661 atacaaaaac tattggaaac cttaaaacaa acccaaatat taaagaataa agtgttgcac
    27721 atctccagat gccttttgta ttaccttctt cagcatactt atctgcctta tgaaccaata
    27781 cagcattacc agttcttctt aagttattaa ctaatactcc tataacacct aaaggtaccg
    27841 caatagatac tgcaacttct gcattaacac cagtttgaag tgctactggt attgcaataa
    27901 gagcagctag acatttatct gatggaatat ttccccctgc tgcgaccatt cctagataaa
    27961 ccatttctat acttgcacca acaatcatac cagttgttac atcaccccaa agtaatccaa
    28021 ggctaaaacc tataaataaa ggagacttta gtgttgagaa aagggtatac cctgcaagac
    28081 ctgctgcaaa ccaataccat aatcctgtta caattgccaa catcaaaaca gattccattt
    28141 ataattcctc ctaatttata ttttttattt aaatttcttt aacgcatttt catatgtcat
    28201 agatgattcc tctggtataa cttgtaggac tatttcaacc ccattttcat taagttcatt
    28261 aagttgttct acatcctcat ttcctaatga aacagctgta aacaccattt tctttcctgc
    28321 ttcatttgga atacctccta attgaatctt ttcatattta agtccagctt tataagcctt
    28381 atttgccata tcaacatttt taaatagaat aaatatattt ttatctccta aagtgttgtt
    28441 ttggaatgct tgtcccgcat cttctgctgt taaaataact acttctactc ctgatggtgc
    28501 tgccatttta tatatgtcag ccataaattc atcttgacct aagaagtcat caactattat
    28561 tattttttga gcttgagcga tttttaccca ttttgttata acttgcccat gaattaatct
    28621 gtggtctact cttactaatg ttatttttgc cattatattc acctcataat ttatattttt
    28681 ttaaattctt taattaaatc cacacaaagg ttattatttt ttttgacgat tctttctggt
    28741 aatgtatgta atttatcttc tttgcttaat tcttcatcta cgattaaaat tgtctgtaag
    28801 ctaagtccat ttattgcatc tattcctctt cttatagcaa cagctattgc gacacttgat
    28861 gtagatcctc catataaatc tgatattata attttcacat cttctttatc tactacttct
    28921 tcaacctctt tcataaatac agaaacatct ttttcagaac ttagtgataa aacttcatat
    28981 tgatttgaca atccaaagtt tttatttgtt tcttctacta agacttttcc ccaagttcca
    29041 tggcacagta tgattacctt atatttattc attgctaaat aaactctcct ttatagcgat
    29101 taatattttg gtttaattct acttcttctt catcaggtac catttgaatt gatacattaa
    29161 tattcttttt aataaattca tctattaaaa gaaactcttt tttattaatg tatacatttt
    29221 gagatatttt cttttttcct attcctgtag gtattcttcc aacaataagt tttttgatat
    29281 taatcccttc ttctatcatt ctatttgcag tatctaaatt tttaattaat acaaaaacgt
    29341 tatcatcagt ttgattatta taaaaatatc tccttgattc acttacagtt aatatcgata
    29401 aatcaatatt ctttggtgct gccattttta tcaaaccttt agcaataaca tcattggttg
    29461 tttcatcatc tactactact atctttttta cacctagatg cttaacccat ttatatataa
    29521 cttgaccatg tattaatcta tcatcacatc tgcaatattt tactaaagac atttttaatc
    29581 aaactccttt ttctattaca ttgagctaag aactttatta atattgttta taccagtttg
    29641 tcctgcttca atacatgctt ctgctaactc ttctaaactt tttccctctc tattaattaa
    29701 agcttcaagt agcattggaa gatttactcc agtaagtgca tgaaacttgc cacctttttt
    29761 aaggtttaaa cttgcaacat tacttggcga acctcctaat aggtcagcta atactaaaac
    29821 tccgtcacct tcatctaatt catttaactt ttctacaaaa tttttattta agtcttcaat
    29881 attatcattc ctatttagtt taattgctgc tgttctttct gctggtcctg caataagttc
    29941 acagcttttt ataatttctt cactaaaact cccatgagtc ataactatta ttcctatcac
    30001 caatttcacc tcacttttct tgtcactttt tatataagca attgccgtgc caacttatgt
    30061 gtatcaataa caaatggcta ttttacagga tttaatcaaa actttttact caattttttt
    30121 taaaaactta ttatttcgat atgtgtcaaa agattttttc aacctgtatc aaatctgtat
    30181 caaaaaaagt aaaaaaaaga tagccttttg gctattttta aattttgtat caacttttga
    30241 atttatctgt atcatattgt gattcaaata tatctaatat atttgcatat tccatatctg
    30301 aaataattat atcgaatgtc tcttctacta gcttaaaact ttcttttata actaaatata
    30361 attctttatt tctactaatt ctttcttcat atgatttata aactaaagac tcttttatta
    30421 ttactctttc aatcatacat gaacaatgaa atataaactt tactaaaagt tcatcttgaa
    30481 ttactaaaga atagtgttca ctaattctat taattacttc ttttaatata aaataagcct
    30541 tttccccatt taaaaaagtc aaagttttac taatattatc aattagtaat ctatcaaaat
    30601 atctaccacc attatctttt tcagcatatg taacttccat atctccataa tgtttcttta
    30661 tagattctat aatattaaaa tataatttct ctaatgtcat ttctggagtt agagcctttc
    30721 tagttgcttc tattacaata ggtgtactta ccatatctat tgcttttact tcttttcctg
    30781 tagcatcacg aataacttta gcaaatgtta aaatagaccc catatcagtt aaaattaaaa
    30841 ttccttttcc tttatcaatt ttattggcta tttctacagc ttgtactaaa atatcctgaa
    30901 ctctatcttc taatcccata ttaattgcca ctgcatggtt acaatccagt aaagtattgg
    30961 ctacattcac catgctagat gctgtagatt caccatgcat tatgactaat attgctatac
    31021 tctcctcatt taatcccaca tacgataaat aaagaaatgt tgctaaaaaa attgcttcat
    31081 cttctggaaa ctctactcca tacattaatg acatgttaga taatatttct tttgctatgt
    31141 tatattcata tgctctttcc ttcataattt catctttatt aggatgcttt actatatttc
    31201 caatctttat tctttcaatt aaattctgaa tatgtaaagc tatagctttt attaatttat
    31261 ctaatccttc tcttttgctc catttatcat gcttttgtaa aatatatttt acagtagttg
    31321 caattgaatc attaacaatg ttgttataag ctgtttgatt actactatta tatataaaag
    31381 tattcattaa attataggaa tacttctgta tgtctccatc tataacactt ctaatttgtg
    31441 actctttaat accttcttgt tgaagtttat tccaagtttc ttttatcatt ccataaaaat
    31501 ctaaatcata ttttttattt tctattaata aattttcact ttcaaaatcc ttttcttctg
    31561 gtaaaaaaat aatatcatct tttccaataa aactgaaatt ttgtacaaac tcctcttttc
    31621 tattatttcc atataatgat tctctaatat tatttggtag aagagagagc cttacatata
    31681 cacattccct tttataggtc atataatcta aaaaagctct tgcacaaatt aattgtatat
    31741 cgctttttaa ttggcctatg tttcccttac acttatataa aataaatgcc ttaataactt
    31801 cttttgaaac ctttaactta acaccaatcc taacactctc ttctttaaaa aaataacata
    31861 taagcttcat tctctcttga aagcctcttt cctctaaaga cggaatcttt atagttacag
    31921 gtattcttct taaaaatgtt tccaacattg ctgtttctgg gtcttctgta gtggctgcaa
    31981 ttatcataac tctacactcg tgtaccttat tagcctctcc taaccttcta tatatccctt
    32041 tatccataag cagaaatagc atttcttgtc cctctgcaga taatctatga acttcatcta
    32101 aaaacaatac tccattatta gcttcatgta caataccata cttatcttta tcagctccag
    32161 taaatgctcc ttttacatat ccaaaaagct gcgctaataa taattgctga ttatcagaat
    32221 aatcagcaca gttaaatatg ataaatggtg cattatcact atcttctttt atagttaaac
    32281 tatacttata catatattct gcaaatatag atttaccaac tcctgtaggt cctattatta
    32341 atgtacttaa ccccttaggt ggatatatta ctgctgcttt agcctgttct atttgggacc
    32401 ttaaacttcc atcacatcct actaaattaa aaatattgtt ctcttttttt atactctcta
    32461 aaatatactc atctttgata gaatcatttt cactatattc gtttatagag ttaatattat
    32521 caaatatccc tttatttagt ttctttccta aaatactctc aatactttct ttatataagt
    32581 actgaacagg cttacccttt atctttataa taatactttc ttttattaat tgatttaatt
    32641 ccttactagc attacttcta tttataccta cttcagtagc tatatattct gcatcaaatc
    32701 caaatctaat gccattatta aagttcaagt gttcttctgt taaccttttc aagcaaatta
    32761 aaactttttc tttccttgat agcttctttt gtgtcatagt taacctcccc tataagcagt
    32821 aatactgtta aacatttatt attaagctta attctacaat attttaatat ttttgtctaa
    32881 ttatgtaact attgattttc tttcctattc gttttataat ataaattacg ttaccctcat
    32941 cttttataga ggaggaattt atatgaattt tttatcagat ttacacaccc actctatagt
    33001 cagtggtcat ggctatagca ctttactaga aaatattaat tattgtaaag aaaatggaat
    33061 taagatacta ggtacatctg aacatggtcc taagatgcct ggttctcccc acagatggta
    33121 ctttcacaac attcaaaata tcccaagaat cataaataac attataattt taagaggctg
    33181 tgaagcaaat atactagata ttaaaggaaa catagaccta gagccttttg taattcctcg
    33241 cttagattat cttattttgt catttcacga agctgtgttt tctccaaata cattagagaa
    33301 taatactaaa gctttaataa atgcaataaa taagcatgat aatattgaaa tattaggaca
    33361 ccttggaaac ccaaactacc caatcgacta tgaattaatc attaaattag ctatagaaaa
    33421 gaatatctta atagaaataa ataattgttc tattaaaggc gtgtcaagaa atggtagctc
    33481 ggataactgt aagtatattg ctacactttg caaaaaatat ggtgctaaaa tcatactgac
    33541 ttcagatgct cacatttgtt ttgacatagg taactatgag tattctgaaa atatcttaaa
    33601 ggaaattaat tttccagatg aattaataat gaattatcct aaaaaactta ttaatcattt
    33661 tcaccaaaaa ggtaaattac tagatgttga ttatacaaat atctaagtaa taatacatgc
    33721 ttactttaac tcccataaaa attttaatac tatttatatt atatgaaata aagaaattat
    33781 aataaagaag ctatttaata aagcttaatt acttttatga acttgatgga ttgatatggt
    33841 ctatgatagc aatagaaatt ataacatttt taataaactt agttttatat accttatagt
    33901 ataaatctaa aaaagcatca tctaaaaagg agctgtcaca tgagcaaatt aaatttgttc
    33961 tatgatagct ctttttttac ttattttaat taggtatatt tttaattatt ttatataaag
    34021 cttatgttct aagtaaaatt atgcataaca aacaaaggta taaaaatacc attttttcag
    34081 ataatattta attataaata ataaatttag aatacttctt ttaaatgatg agagtctaga
    34141 aatttttatg tgtattcttt aaataaaaat ttccagactc tagccccttt ttgaatattt
    34201 taaaatttaa cttaaactaa gcaaattcta taatagct
//
LOCUS       DAEPUT010000040        33647 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.041, whole genome shotgun sequence.
ACCESSION   DAEPUT010000040 DAEPUT010000000
VERSION     DAEPUT010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33647
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.041"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            111..1397
                     /locus_tag="KRL22_002082"
     CDS             111..1397
                     /locus_tag="KRL22_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH1272571.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            1509..1982
                     /locus_tag="KRL22_002083"
     CDS             1509..1982
                     /locus_tag="KRL22_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:1641..1643,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HBH1272572.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            2014..3324
                     /gene="grdB"
                     /locus_tag="KRL22_002084"
     CDS             2014..3324
                     /gene="grdB"
                     /locus_tag="KRL22_002084"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:3061..3063,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBH1272573.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            3580..5112
                     /locus_tag="KRL22_002085"
     CDS             3580..5112
                     /locus_tag="KRL22_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HBH1272574.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            5123..6268
                     /locus_tag="KRL22_002086"
     CDS             5123..6268
                     /locus_tag="KRL22_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HBH1272575.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            6578..7657
                     /locus_tag="KRL22_002087"
     CDS             6578..7657
                     /locus_tag="KRL22_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1272576.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATRLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            7770..8369
                     /locus_tag="KRL22_002088"
     CDS             7770..8369
                     /locus_tag="KRL22_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272577.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(8556..9428)
                     /locus_tag="KRL22_002089"
     CDS             complement(8556..9428)
                     /locus_tag="KRL22_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1272578.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            9845..11248
                     /locus_tag="KRL22_002090"
     CDS             9845..11248
                     /locus_tag="KRL22_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272579.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            11275..12819
                     /locus_tag="KRL22_002091"
     CDS             11275..12819
                     /locus_tag="KRL22_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH1272580.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            12850..14241
                     /locus_tag="KRL22_002092"
     CDS             12850..14241
                     /locus_tag="KRL22_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HBH1272581.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEVVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            14434..15930
                     /gene="abfD"
                     /locus_tag="KRL22_002093"
     CDS             14434..15930
                     /gene="abfD"
                     /locus_tag="KRL22_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HBH1272582.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            16065..16340
                     /locus_tag="KRL22_002094"
     CDS             16065..16340
                     /locus_tag="KRL22_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272583.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            16364..17671
                     /locus_tag="KRL22_002095"
     CDS             16364..17671
                     /locus_tag="KRL22_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH1272584.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            17691..18809
                     /locus_tag="KRL22_002096"
     CDS             17691..18809
                     /locus_tag="KRL22_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH1272585.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            19096..20016
                     /locus_tag="KRL22_002097"
     CDS             19096..20016
                     /locus_tag="KRL22_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBH1272586.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTVS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTSEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGNKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            20131..21288
                     /locus_tag="KRL22_002098"
     CDS             20131..21288
                     /locus_tag="KRL22_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH1272587.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(21373..22872)
                     /locus_tag="KRL22_002099"
     CDS             complement(21373..22872)
                     /locus_tag="KRL22_002099"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBH1272588.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            23468..24892
                     /locus_tag="KRL22_002100"
     CDS             23468..24892
                     /locus_tag="KRL22_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBH1272589.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDALFKRLESK"
     gene            24927..27056
                     /locus_tag="KRL22_002101"
     CDS             24927..27056
                     /locus_tag="KRL22_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH1272590.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLIDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            27086..27508
                     /locus_tag="KRL22_002102"
     CDS             27086..27508
                     /locus_tag="KRL22_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1272591.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            27527..28678
                     /locus_tag="KRL22_002103"
     CDS             27527..28678
                     /locus_tag="KRL22_002103"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1272592.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEDILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      28784..28885
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            29068..29640
                     /locus_tag="KRL22_002104"
     CDS             29068..29640
                     /locus_tag="KRL22_002104"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBH1272593.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            29704..30354
                     /gene="fsa"
                     /locus_tag="KRL22_002105"
     CDS             29704..30354
                     /gene="fsa"
                     /locus_tag="KRL22_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH1272594.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            30506..33430
                     /locus_tag="KRL22_002106"
     CDS             30506..33430
                     /locus_tag="KRL22_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1272595.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LR"
BASE COUNT        13217 a         3753 c         6339 g        10338 t
ORIGIN      
        1 ataaaaacac aataatatat ctttaaaaaa ataagataaa ttgtaaaatg atataatttt
       61 gagaaaaact caaatgcata tacacaaatt aaataacagg aggtgcaagt atgcgtcttg
      121 aattagggaa aatctttata aaagatattc aatttggtga tgtaacagaa gtaaaagatg
      181 gagtattatt catcaataag caagagatgc tacaagaaat tggtggagat gagcatatta
      241 aatctataga tatagaatta gctcgtccag gtgaaagcgt aagaataaca cctgtaaaag
      301 atgttattga gccaagagta aaagttgaag gtaatggggg aatcttccct ggtatcatgt
      361 ctaaagttga cactgtagga gaaggaaaaa ctcatgcttt aaaaggtgta gctgttgtaa
      421 ctactggaaa aatagtaggt ttccaagaag gtataataga catgactgga gaaggagcta
      481 agtatactcc attttctaaa ttaaataatg tagtagtaat agctgaacct attgatggtt
      541 taaaacaata cgctcatgaa aaagctgtta gaatgatagg attcaaagca gcaatgtact
      601 taggagaagt agcaagaaat cttactccag atgaagtttc agtatatgaa actaaacctc
      661 ttcttgaatc aataaaagaa tatccagagc ttccaaaagt aggatatgtt tacatgcttc
      721 agactcaagg tttattacat gatacttatg tatatggagt agatgcaaaa caaatagtac
      781 caactttatt atatccaaca gaattaatgg acggagcaat tgtaagtggt aactgtgttt
      841 ctgcatgtga caaaaaccca agttatgttc atataaacaa tggggttgtt gaagacttat
      901 atgcaagaca tggtaaagat ataaactttg taggtgtaat tataactaat gaaaatgttt
      961 atctagcaga taaagaaaga tcttcaaact ggacttctaa attatgtaaa tatttaggat
     1021 tagatgcagt tatagtttca caagaaggtt ttggaaatcc tgatactgac cttataatga
     1081 actgtaagaa gatagaaatg caaggtgtta aaacagttat agttacagat gaatatgctg
     1141 gacgtgatgg aggttctcaa tcacttgcag atgcagatgt aagagctgat gctgttgtaa
     1201 caggtggaaa tgccaaccaa gttgtagttc ttcctaagtt agataaagtt attggacatt
     1261 tagaagtagt agatgtaata gctggtggtt ctgatggaag tttaagagct gatggaacta
     1321 ttgaagttga aatccaagct ataacaggtg caactaatga aacaggattt ggtcatttaa
     1381 ctgctaaagg atattaagaa gtattttatt aaacgattga gtaatgttaa taaaacatat
     1441 tatagataat tataataagt gttatagata tataaaaata tattagaaat ataataagga
     1501 ggattattat gagtttactt agtaataaaa aggttcttat aataggtgac cgtgatggta
     1561 taccaggacc tgcgatagaa gaatgtgtaa aaacagtaga aggagcagag gttgttttct
     1621 catctacaga atgctttgtc tgaacagctg ctggggctat ggacttagaa aatcaaaaca
     1681 gagttaaaga tgctgctgat aaattcggag ctgaaaatgt tgtgatttta ctaggtgctg
     1741 ctgaagccga agctgcaggt cttgcagccg aaacagtaac tgctggagat ccaactttcg
     1801 ctggaccact tgctggagtt gccttaggat taagtgttta ccacgttgtt gaggaaccaa
     1861 taaaatcatt atttgatgaa agtgtatatg aagaccaaat aagtatgatg gaaatggttt
     1921 tagaagttga agaaatagaa gaagaaatgt ctggtataag agaagaattt tgtaaatttt
     1981 aatgcctaaa agcaaaaggg gtgaaactaa gagatgggaa aactaaaagc agtacattat
     2041 attaatcagt tctttgctgg tataggtgga gaagaaaaag ctgatactaa gccacatgtg
     2101 gcagaaactt tacctccaat aagtttacaa cttgataaat tattaggtga agatattgaa
     2161 atagttggaa cagtagtttg tggagatagc tatttcaatg agaatataga tagtgcaagt
     2221 gaagaagttt tatcaatggt aaaaggtttt gaaccacaac ttttcatagc tggtcctgca
     2281 tttaatgctg gtagatatgg ggttgctgct ggaacaataa ctaaagttgt aaaagatgct
     2341 ttgaatatac cagctttaac aggtatgtat gttgaaaatc caggagcaga tatgttcaaa
     2401 aaggatgttt atgtagtaga aacttctgat tctgcagcag gtatgagaaa ggcacttcct
     2461 aagatagcta aacttgcagt aaaacttgct aatggagaag aaattggaac tcctaaagat
     2521 gaaggataca tagctagagg aataagagtt aactacttcc atgaagacag aggttctaag
     2581 agagctgttg acatgttagt taagaaaata aaaggtgaac catttgaaac tgaataccca
     2641 atgccaaact ttgatagagt tgacccaagt aaagctgtaa aagatttatc aaaatgtaaa
     2701 atagctttag ttacttctgg tggtatagtt ccaaaaggaa atccagatag aatagagtct
     2761 tcttcagctt ctaaatatgg aacttattct atagcaggag ttatggattt aacagaagag
     2821 acttatgaaa ctgcacatgg tggatatgac ccagtgtatg caaatttaga tgcagataga
     2881 gtattacctg ttgatgttct tagagattta gaaaaagaag gtgtaattgg aaaattacat
     2941 gagactttct atacaactgt aggtaatggt acatctgttg caaactctaa aaaatatgct
     3001 tctgaaattg gagcagcatt agtggctgat ggtgtagatg cagtaatatt aacttctaca
     3061 tgaggtactt gtactcgttg cggtgcaacg atggtaaaag aaatagaaaa aactggactt
     3121 ccagtagttc atatgtgtac agtagtacct atttcattaa cagtaggggc taatagaata
     3181 gttccaacta tagcaatacc tcatccactt ggaaatccag cgcttgaccc tacagaagaa
     3241 aaagccctaa gaagaggcct tgtagaaaaa gcattaaatg ctttaactac agaagtagat
     3301 ggtcaaacag tatttgaaaa ataaaaataa cacacacata tattatatag ataaaaatat
     3361 aaacacacac taaaaataaa aaataactat acacaaaaaa ataatataga tttcatgaat
     3421 ggataaattg gagttattca ttcatgaaat cttaaaaaat gccaaaatac ataaacaata
     3481 atagaatcaa atatacaata aaatacaatg attagagctt ttaataagtt taataagatt
     3541 aaaaaataag tgttcataaa atttatggag gtgcacaaaa tgacttatcc agttttaaaa
     3601 ggggcaggct atgtacttat tcatactcca gatatgatag tgcaaaatgg aagtacttgt
     3661 acagttgaaa gagcaacaaa tccagattca gaatttttaa aagaagtaag taatcatata
     3721 agaagttatg aagatgtagt taactacatg ccaaatcaag tttatatagg aaatagaaga
     3781 ccagaagaat taagagattt accaatgcca tggtgtgaac aaaagattga gggaactaga
     3841 aatggtaagt ttggagaaat aatgcctcaa gatgagttca tagctttaat gcaaataagt
     3901 gatgcatttg atttagtaaa attatcacaa gaatttattg atgaagtaaa gccaaaaatc
     3961 gaaaataact accctgaaat tgcaccattt gtaggtaaat taaagggtga tgatatagaa
     4021 gaaggtaaag aattagtagc aacacacata gctgaaggat tataccatga tggaaaattt
     4081 gttggttatg taaaaagagc acatgatgta gatgttaact taaatgccca tacaatgttt
     4141 gaaaatctag tagtaaaagc atctggagtt ttatctgcta ttcaaatgct aagacatagc
     4201 aaaatagacc ctgctgaaat agattatgtt attgagtgtt cagaagaagc ttgtggagat
     4261 ataaaccaaa gaggtggagg aaactttgct aaatcaatag ctgagatagc aggacttcaa
     4321 aatgcaactg gttctgacac aagaggattt tgtgcagcac caactcatgc attaattcaa
     4381 gcagcagctt tagtaaaagc tggcatacat aaaaatgtaa tggtagtagc aggtggagca
     4441 agtgctaaac ttggaatgaa tgctaaagac catgttaaaa aaggtcttcc tgtacttgaa
     4501 gatgttgttg gaggatttgc agtacttgta tctgaaaatg atggtgtaaa tccagttata
     4561 agaactgatt taacaggtaa gcatactgtt ggaactggtt cttcaccaca agcagttatg
     4621 acagcactta taacttcagg tcttgataga gctaatttaa aaataacaga tgttgatgtg
     4681 tattcagttg aaatgcaaaa cccagatata actaagccag caggagcagg agatgttcca
     4741 gaagcaaact acaaaatgat aggggcactt gctgttaaac gtggagactt agaaaagaaa
     4801 gaattgaaag attttgtttc taacaaagga ttaccaggat gggcaccaac tcaaggacat
     4861 ataccatcag gagctcctta tataggattt ttaatagatg atttaactac aggaaataga
     4921 aatagagcta tgatagttgg aaaaggtagt ttattcttag gaagaatgac taacttattt
     4981 gatggagtat cttttatagc tgaaagaaat acaggtgtta ctgaagagac ttcaggaata
     5041 tctaaggatg aaattaagaa gataatagct gaatctatga aaaaactagc attagatatg
     5101 ttagaagaat aggggtgagg atatgtcaaa aaaagtaatc gcagatgtat tcttagaagt
     5161 agctaatgca atagaaagcg gcgaatttgg caaaaaagta aaaattggtg ttactacact
     5221 tggaagtgaa catggtgtag aaaacatggt taatggtgca caattagcaa aatctaattt
     5281 atttgatatt gtgcttattg gaccaaaagt ggaaactgac cttgaagtag ttgaagttaa
     5341 tgatgaaaaa gaaatgcatg caaaaatgga agaattatta gattcaggat atattgatgc
     5401 ttgtgttact atgcattata attttccaat aggtgtatct acagtaggta gagtaataac
     5461 tccagcaaaa ggaaaagaaa tgatacttgc aacaacaaca ggaacaagtg ctactaatag
     5521 aatagaggca atggtaagaa atgccattta tggtattgct acagctaaat caatgggtaa
     5581 caaatgccca aaagttggaa tacttaatgt tgatggagca agacaagttg agaagtgctt
     5641 aaaagaatta aaagataatg gatatgacat ggagtttgcg gattcaatta gagcagatgg
     5701 tggatgtgta atgagaggta atgatttact tgtaggtgca cctgatgtta tggttactga
     5761 tacattatct ggaaatatat ttatgaaagt attttcttca tatactacag gtggagatta
     5821 tgaagctcaa ggctttggat acggacctgg agttggagag gactatgata gaaaggtact
     5881 tatagtatca agagcatcag gttctccggt agtagcaaat gctttaaaat acgcttatga
     5941 tgttgtaaag ggagatataa gtaatgttgc aagaaatgaa tttgcaaagg ttaaaaaagc
     6001 aaaatttgat gacattatat cctctcttac taaaaaagaa gttaaagctg aaaaagtaga
     6061 agttaaaatg ccagataaag aaattgttac tcgtcaaata gctggtgttg atataatgga
     6121 tttagaagat gcagtatctg agttatggaa aaacggaatc tatgctgaaa gtggtatggg
     6181 ttgtacaggt ccaatagttt tagtaaatga agctaaagga gacttagcag ttgaaacttt
     6241 agttaaagct ggatatactg caaaataagt acatttttta tatgtaaata agaacatata
     6301 gttataattt tattgattat aattatatgt tctttttatt ttatatcttg tcaatattta
     6361 tatattaaca caatccattt atttgattct ctagctaatt tattatattt attcaattaa
     6421 aattaagctt tctaactaaa taaaaactaa tgaagtatta aaatgaaatt gataaaatat
     6481 gaaaaaattt taggaataaa gtatctgtta gataaaaata agattaatta gtgatataat
     6541 ataattaaga taaaatttat tatttggagg taaaatcatg agcagagtaa aaaatgtagt
     6601 agaattgttg gaaactaaag gtgttgatgc actatatcta acaaagaaaa ctaatgtaaa
     6661 ctatataagt ggttttcctg atgaagaagc atatgcagtg atttgcaaag atggaaactt
     6721 tttagttact gatagtagat atatggagct tgcagaaaag gtttgcaaag attttgaaat
     6781 tataaattgg cataattttg atagaagtgt ggcaaaggca gttaaaagtg tatgtgataa
     6841 agtgggtata aagaaacttg gatttgaaag aactaatata gtgtttgata aatatgaaga
     6901 acttaaaaat ctgattgaga aggataatgg agaattaata cctacagaaa atattgtaga
     6961 gactttgaga tatgtaaaag acaaagatga aatcaaaaat acaagaaaag cttgtgaaat
     7021 agcggataag gcattagaag aattgattcc acatataaaa gctggagtta gcgaaattga
     7081 actggctaca aggttagagt actttatgaa aatgaacgga gcacaaaata tagggtttga
     7141 aactatactg atatcaggag caaagacttc attgcttcat ggtaagccta gtgataagat
     7201 tatagaaaaa ggtgattttg tacttataga ctatggtgct atgtataatg gctatatatc
     7261 tgatacaact agaactttta tagttggagg agcttctgaa aagcaattag aaatatataa
     7321 tttagttaag gaagctcaaa atgtaggggt tgagaacatg aaagctggtg tacatgcgac
     7381 aattccagat gctgagataa gaaaagttgt caaaaaatat gaagactatt actatcaagg
     7441 tataggacat ggagtcggta gagatgttca tgaagaacct ttcattggta attatggtga
     7501 taaaatcata gaagagggat gtataataac aatggaacca ggtatttatt tccctggatg
     7561 gggtggagtt agaatagaag atactgtttt gattactaaa aatggtccag aaagacttac
     7621 taaattccct aaagatttga tgattttaga caaataattt aatttatata tattttttta
     7681 cataaaatat aacataatct cactattaag ctctatttac atattatagt aaagagggct
     7741 taattttatt gtgagaggtg atagtatata tgtataaaaa acataaattt ataaaaaata
     7801 taaaaaaagc ctggtataaa atcaaattaa ttgatagatg ccttataatt gtaatggcaa
     7861 tattaatgtt tcaatctata tataacttat ttgttaatga agtaaattca caagatacta
     7921 caactattga tgtagtagta agaaccactt cagcagctat atttgggtat tttttaagtg
     7981 ctaattttat aaagagacct ttaaggaagt atacaaatac tgatgtatct tcaaatcttt
     8041 ttatagataa taatttatcc ccaaaaggtc aagagtctaa tcaaaataat ataatgaatg
     8101 tcaaaaatac cattggattt acttcagaag ctgataatta tgaaaagaaa atacctatta
     8161 ataataatga aggttttgaa gaaggagaaa ctagtgaatt gcaaattatt atagctactg
     8221 taatttgcat agtagcatta acagtacttt ttgttgtaag aaattttaca actacaacat
     8281 cagcttcttt aggtactatt tcacagatga gagattttgt ctcaggatgc gtgggttttt
     8341 tgctaggttg tccaagtaaa cctgattaaa aaagtattat caataaaagg tattttaaaa
     8401 agtatcagta taataatatt tagatttaaa tgtatacaat tataattctg taacattcta
     8461 tattgtattt ttatactgat actctaaact atactattta ttaaaatatt ttaacattgt
     8521 atttaaacaa aatattatat ctgtataata taaatttagt ttatatgaat agatgccata
     8581 tactcaataa aaagtttcat actatgagat atgtattgat ttcttctcca aagaacccca
     8641 atatttgcag taattgcacg ttctaatggt attgaacaga gattttctgt attttgaaat
     8701 atttctttat acaatattgt tgaagccaag tcattttcta gtaaataacg tatggtagaa
     8761 agttgatttg agtgtaaaat tatatttggc ttagcttttt caagtctttt tgtaataatc
     8821 ttatagtgat aagaaccttc agataagatt acaaaaggta cattttttaa catataattc
     8881 gatataatag gatgttttgc caattcattt ttgggatttg taactaagta taattctgtt
     8941 ttatagattg tctttgaatc tatatcatca taaatatcac tgtcaattat accaatacaa
     9001 aaatcaagtg tagattcttc aatcatttta gctccaacaa atgttggaac ttcaaaaatt
     9061 ttaagctcta tatctggata aattacatta aacctaggaa gtatttttga aagcaaaaac
     9121 gtacctaaaa ctgtaggaat acctattttg agagaagctt ttctcttttt tcctaaatca
     9181 agtgcgtcac attgaaaatc ctcaaattgt tttataaaat gttttgactt gtctaaaaaa
     9241 atttttcctt caggcgttaa ctctatttta ttacctattc tgtaaaaaag ttcaaagcca
     9301 agttcttttt ctaattcttt aattgctaat gttatggatg gttgagaaat atgaatactt
     9361 tccgcagcct tagtcatgtt tttatattta cagacagttt gaaaatagta taaatagttt
     9421 atattcattt ggtattagtt cctttcattt acatattagt gacaagtata taattaacaa
     9481 tagcataagt tttgtatatt gttgtaaaaa aatagaatag ttttaaacta tcatagcata
     9541 agtttttgat attttcaatc tattaagaat agtgctatta ttaaattaac aaaagagaat
     9601 agctggtatg gtttagagta aatcaatcta tattacagtt atatcaacga atatcaaaaa
     9661 attatctatt aaaaaataaa aattattttt acaattaaat tgttaattaa atcataaaga
     9721 aaaaagtgat attaacaaga taaaattttt ttaatcagaa atgttaattt aataacaaaa
     9781 tagagtattg gggagaaagg agaaatatat tttttaataa tatttgttaa tttaataacg
     9841 aaaaatgaaa gggagtgatt tagtgaagtt tgaattgatg gattttttaa tgaatccttt
     9901 tgtccttatg tttgctgcag taattacagg aattttattt ggaaaaatta aatttgggaa
     9961 gtttaatttt ggggtatcag gagcattatt tacaggatta tttattggat ggcttgcata
    10021 tagcttgggg aatctaataa tagcaaaagg ggaaacagca gcaggatata aggcagcaac
    10081 tgtaatgatg gggaatggaa ttatttcttc tgacttcttt gatttctttt taataatatt
    10141 tgttgcagca gttggtctat tggcagcaaa agatatgaaa gctgtattaa agaagtatgg
    10201 agcaagattt gtaattttag gagttcttat aacttttata ggtggctcta tgacttatgc
    10261 aatgacttta ctatcaagtg ataaaggaag tagtgcttat gaagtttctg gcgtttacac
    10321 aggagcatta acaagttcgc ctggattagc tgctgcttta gaaacagctg gtaaacatgc
    10381 agaagatgta tcaaaagaat ttgaaaaagc atcaataaaa gataaaaaag aaattttaaa
    10441 agtagtcgac ccagaaggca aattggatgt gaatacaact acatcactga ctcaagagca
    10501 aatagataag tatattgcat atgctgaagc tggtgttggt ataggtcatg cagtcgcata
    10561 tccttttgga gttttaatag taatcttagg tgtaaatttc cttccaaaat tatttaggat
    10621 ggacctaaaa gaagaaagaa gaaaatatga gaaggaaatg aaggaagcaa gagatagtgt
    10681 ttctggtaaa acgataccag aagttccatt taatataata acatttttct tgacatgttt
    10741 agctggatac ttagttggag gaatacatgt atttatggga ccactagggt acttcacact
    10801 aggtgcaaca ggaggttcac taattgtatc tctagttctt ggatatatag gtaagatagg
    10861 ggtagtaaat ttcagaatgg aagaaaaggt tttaaatatt ttaaaacaaa tagggctagt
    10921 atttttctta gcaatagttg gattaagata tggtggaaaa gtagttgatt caattatgac
    10981 atctggtatg cacctagcct tagtagcaat agcagtaggt gttacagcta tgatgatagg
    11041 attcttagtt ggcaaatacg tatttaaatt aaattggatt ttattatctg gagctgtctg
    11101 tggtggtatg acatcaacac caggtcttgg agctgctgtt gatgctcttg atagtgatga
    11161 cccagcagca ggttatggcg ctacgtatcc atttgcatta ttaactaaag ttatattggt
    11221 tatagtttta cacaaacttc caatgtaaat aagattttat atggggggat atttatgaat
    11281 aatgaaggag catttgaaga attaagtgga agattaagaa ataaagaatt gtgtgattta
    11341 ataatgaatg cagatgaagc tgctaaaatt atagaggatg gcatggttat tggagttagt
    11401 ggatttacac cttcaggcta tccaaaagca gtaccattag cagtttcaga aagagctaaa
    11461 agtggagaaa agataaaatt aaccgtatat tcaggagcat ctttaggtcc agaagttgat
    11521 ggagcatggt cagaagcagg tataattgaa agaagacttc cttatcaaac taattcaata
    11581 cttagaaata atattaataa aggtgttgtt gattatatag atatgcacct aagtcattct
    11641 actcaatttt taaattatgg aactatacct aaagtagatg tagctatagt agaagcactt
    11701 gcaataactg aagaagggaa tattatacca actagtggga taggtaattc tccatctttt
    11761 ataaaaagtg cagataaagt aatagtagag ataaatcttg caaaaccaat ggaaatggaa
    11821 ggtatggcag atatatatat tacggaaaat ccaccaaata gaaaaccaat agaaataaat
    11881 catcctaagg atagaattgg aacaacatat ataccttgtg gtttggataa aattgcagga
    11941 gtagtaatta ccaatatgca agataagacc cgtccattgg gggttgtaga tgaagcttcg
    12001 aaaaaaatat caaataatat tattgctttt ttaagagaag aagtaaaggc aggcagatta
    12061 tcaaagaatt tacttcctct tcaatctggt gtaggaagtg tagcaaatgc agtattatat
    12121 ggattatgtg aatctgaatt tgaaaattta acttgttata cagaggttgt acaggactct
    12181 atgttggatt taataagaat gggtaaagtt acaatggcat ctactacatc tgtaagtcca
    12241 tctccagaag gattaataaa atttgaaaaa gatattgatt tttttaagga taagattata
    12301 ttaagacctc aagaaattag taacaatcca gaaatagcca gaagaattgg tgtaattgca
    12361 atgaacactg caattgaagt tgatatttat ggaaatgtaa attctactca cataatgggg
    12421 tcaaagatga tgaatggaat tggtggttct ggtgattttg ctagaaatgg agcaataact
    12481 atatttagta ctgagtcaat tgcaaaaaat ggtgatatat catcaatagt acctatggta
    12541 tctcacgtag accacactga acatgatgta atggtaattg taacagaaca aggatatgct
    12601 gatttaagag gtcttgcacc tagagaaaga gctataaaaa taatagaaaa ttgtgcccat
    12661 ccagattata aagaacaact tagggattat ttaaatagag cttgtaaaag tggagcaaaa
    12721 caaacacctc acatattgga cgaagcttta tcatggcata gtaaatttat gagtacaggt
    12781 acaatgaaaa aggctgaaac ttttaaaagt gcattataaa atatttaata aattggaggt
    12841 agattttaaa tggaaaaagc agtggaaaac tttgaagatt taagtaagga atacattaat
    12901 ggttatattg agagagcaag aaaagctcaa agagagtttg aatgttatac tcaagaacaa
    12961 gtagataaaa tagtaaaaat agttggaaaa gtagtgtatt ataatgctga atatttagct
    13021 aaacttgctg tagaagagac tggaatggga gtatatgaag ataaggtagc taaaaataaa
    13081 agcaaagcaa aagttatata taacaattta aaagataaaa aatcagttgg tataattgat
    13141 atagatagag aaactggaat aacaaaggta gctaaaccag ttggagtagt agcggcaata
    13201 actccttgta caaatccaat cgttacacct atgagcaatg caatgtttgc acttaaggga
    13261 agaaatgcaa ttattatcac acctcatcat aaagcaattg gatgtagtac aaaaactgta
    13321 gagatgatta atgaagaatt agaaaaaata ggagctccag aaaatttaat acaaatactt
    13381 gaccaacaat caagagaaaa tacaagaaat ttaatttcat cagcagatgt agtaattgcc
    13441 actggaggaa tgggaatggt aaaagctgcg tactcaagtg gaaaaccagc acttggtgta
    13501 ggggcaggaa atgttcaatg tatcatagat agagatgtag acattaaaga agtagtacct
    13561 aaaatcatag caggaagaat ttttgataat ggtatcattt gttcaggtga acagtcagta
    13621 atagtagcag aagaaatgtt tgataaaata atggatgaat ttaaaaataa caaaggtttt
    13681 atagttagag ataaagtaca aaaagaagct ttcagaaatg ctatgtttgt aaataaatct
    13741 atgaataaag atgcagtagg tcaatcagtt catacaattg caaaaattgc aggtgttgag
    13801 ataccagaag atacaaaaat aatagtaata gaagctgatg gaccaggaga agaggatatt
    13861 attgcaaaag aaaaaatgtg tccagttata tctgcataca agtataaaag ttttgaagaa
    13921 ggtgtagcta ttgcaaaagc aaatttaaat gtagaaggaa aaggacatag tgtatctata
    13981 cattcaaata cagttaaaaa tatagaatat gcaggagaaa atatagaagt atcaagattt
    14041 gttattaatc aatgttgtgc tactagtgct ggaggaagtt tctttaatgg tcttgcacct
    14101 actaatactc taggttgtgg ttcttgggga aataacagca tctctgaaaa tcttgattat
    14161 aagcatctaa ttaatatttc tagaattgct tattatatgc cagaaaatga agtccctaca
    14221 gatgaagaac tttggggata aaatttagac aaaaaatatt cattctaaat taaagtagga
    14281 atatacttta atttagaatg aatttaagac ataaattaaa tttaaattag tttattggac
    14341 taaatttaaa atattaagag acatatagaa gaaggaagta ttataattta aaataaataa
    14401 aaaaatctat aaaagagaag gagtggtttt attatggcat taatgacagg agctcaatat
    14461 attgaaagtt tgagaaaatt aaatactaag gtttatatgt ttggtgaaga ggttaagaat
    14521 tgggttgacc atcctatgat tagaccatct ataaattgtg tagcagcaac ttatgactta
    14581 gctcatgacc cagaatatgc agatttaatg acagttactt caaatatcac aggtgaaaaa
    14641 ataaatagat ttggtcatct tcatcaaagt gttgatgatt tgataaaaaa agtaaaaatg
    14701 caaagactat gtggtcaaaa aacagcttct tgtttccaaa gatgtgttgg tatggatgcg
    14761 tttaatgcag tgtattcaac aacatttgag tgtgataaag cccatggaac taattatcat
    14821 gataattttg taaaatactt aacttatata caagaaaacg atttagtagt tgatggagct
    14881 atgactgacc ctaagggaga tagaagtcta tcacctagtg ctcaacctga cccagatatg
    14941 ttccttcata tagtagaaag aagagaagat gggataattg taagaggagc aaaggcacat
    15001 caaactggtt caataaattc acatgagcac cttataatgc ctactataag tatgactgaa
    15061 gcagataaag actacgctgt atcatttgca gttccttcag atgctgaagg agtgtttatg
    15121 atttatggaa gacaatcttg tgacactaga aaattagaag aaggtgcaga tgttgattta
    15181 ggaaataagg agtttggagg tcaagaagct ttagtagtat ttgataatgt atttgttcca
    15241 aatgatagaa ttttcttatg tggagaatgg gatttctctg gtatgttagt agagagattt
    15301 gcaggatacc atagacaaag ttatggtgga tgtaaagtag gagtaggtga tgtaataata
    15361 ggagcagcag ctttagcagc tgattataat ggagcaaaca aagcttcaca tataaaagat
    15421 aaactaatag aaatgactca ccttaatgaa agcttatatt gctgtggtat agcatgttca
    15481 tcagaaggtc acaaaacaga agctggaaac tatcaaatag atttacttct tgcaaatgtg
    15541 tgtaaacaaa atgtaactag atttccttat gaaatagtaa gacttgcaga agatatagct
    15601 ggagggctta tggttactat gccttcagaa aaagatttta aatcagacct taaagttgga
    15661 acaagtggaa tgactattgg cgaagtatgt aacaagtatt ttaaagcttc ttcagtggct
    15721 tcaacagaag aaagaatgag aatattaaga ttcttagaaa atatatgcct tggttcatct
    15781 gctgttggtt atagaactga gtcaatgcat ggggcaggtt caccacaagc tcaaagaata
    15841 atgatttcaa gacaaggaaa cataaatcaa aagaaagaat tagctaagaa aattgcggga
    15901 ataaaaaaag aggaagcttt aaatttataa aaagttgata tataaaggga aattatatat
    15961 taatgtgtgt taattaatga aaaaatatgt agtataagag atagttataa aattatggtg
    16021 gtttttagct aagtaaagaa atttttaata aggagaattt acacatgacc tgtggagtta
    16081 gattttgtgg gggctgtaac cctagatacg aaagagggaa ggctcttaca ataatcaaag
    16141 agcacttcaa tggtagggta gattttagta tagcacaaga gaacgtcgag tatgatttgc
    16201 tacttataat tggaggatgc gcaactctat gcgcatccta tcaacaatat aaagtgaaaa
    16261 atgaatgtgt taagatgtgg gattttagcc atatagaaag agttataaat gtgattgaat
    16321 cagcaatttg tgaaacttaa aaaagctaaa tggggggatt tcattgagtt ggcaagaatt
    16381 gtatcaaagt aaattatgta gtgctacaga agctgtaaaa cagattaaaa acggtgatac
    16441 tgtagtattt gcacattgtg taggtgaacc tcctgcacta gtagaggcta tgattgaaaa
    16501 tgctgaacaa tataaagatg ttgagattaa acatatggta agcttgggta gtggtggata
    16561 tactgctaaa ggaatggaag ctcattttag agtaaatcca atgtttgtaa gtggaaatgt
    16621 aagaaaggca attgaaaatg gagatggtga ttttacacct gcattcttcc atgaagtacc
    16681 aaagttgctt agagaaaaaa gattaaaatg tgatgttgtt ttagcacagg taactccacc
    16741 agatgaacat gggtattgta gcttaggaac atcagttgat tatacttatg aagccattaa
    16801 aactgctaga acagtaattg ttcaagtgaa tgaccagttt cctagaacct atggtgaggt
    16861 agtccatgta tcagagtttg actatatagt ggaaaaatca caacctttat ttgaactaca
    16921 acctgcaaag attggagaag tagaagaagc aattggtaaa aattgtgctt cattaattga
    16981 agatggttct actttacagt tagggattgg tgggatacca gatgcagtta tgttattttt
    17041 aactgataaa aaggatttag ggattcattc agaaatgatt tcagatggga ctttggccct
    17101 ttatgaaaaa ggtgttataa atggtaaata taaaaatttt gataaagaaa aaatgacagt
    17161 taccttctta atgggtacta aaaaattata tgactttgca aataataacc ctgcagtaga
    17221 ggtaaaacca gtagactatg tgaatcatcc agcaattata atgaaacaac ataagatggt
    17281 ttctataaat tctgctatac aagttgattt aatgggacag gtagttgcag aggctatggg
    17341 acttagacaa tttagtggtg ttggaggtca agttgacttt atacgtggag tgtctatggg
    17401 tgaagatgga aaggcaatta tagctatgcc ttcaataact acaaaaaaag atggtacagt
    17461 aatttcaaaa atcgtatcta ttgtggatga aggtgcacct ataacgacat caagaaatga
    17521 tgttgactat attgtaacag aatacggtat agcagaatta aaaggaaaat ctcttagaga
    17581 aagagcaaga aatttaataa atatagctca tccaagtgta agagaaagtc tagcagtaga
    17641 atttgaaaag agatttaagg agaaatatta ataatagagg ggtgttaata atggaagcac
    17701 ttagagtagt tccaaagata ttttactttg atacatttaa agaatttaat gaagaattta
    17761 aaataggaaa aaatgattta gtaattacta atgagtttat atatgagcca tatatgaaac
    17821 ctcttggaat agatacaaat ttaatttttc aagaaaagtt tggaacaggt gaaccatctg
    17881 atgaaatgat agactccatg acaaaggaaa tgaagaaata caattttgat agaattattg
    17941 catttggagg aggaacaata gttgatatat gtaagatatt agcacttgat gttccagaaa
    18001 agtctattga tttatttgaa ggagaagtat cacctaaaaa agtaaaagag ttagtagtag
    18061 ttcctacaac atgtggtaca ggtagtgaag taacaaatgt agctattgca gagttaaaat
    18121 ctaaacatac taaaaagggg cttgcagtag aagaaacata tgcagactat gcagtgttaa
    18181 ttccagagac agtaaaaggg ttaccttaca aattctttgt tacaagttcg gtagatgctc
    18241 ttatacatgc tattgagtct tatctttctc caaaagcaag tccatttaca gagatgtatt
    18301 ctctacaagc aataaaaatg attatggatg ggtataagaa gatagttgat aaaggagaag
    18361 aagagagatt taatcatctt agagactttg tacttgcatc aaattatgca ggaattgctt
    18421 ttggaaatgc tggttgtgca gcagttcatg cactatctta ttcaataggt ggagctttcc
    18481 atgttgcaca tggtgaagca aattatcagt tctttactga agtatttaag atgtattcta
    18541 gaaaaaaacc taatgggaaa attataaaat gtacaaaaat tttagcagat gcccttgaat
    18601 gtgaccctaa ctgtgatgtt tatggagaat tagaaaagtt tttaaataaa ttaatagcta
    18661 aaaaagcttt gagagaatat ggaatggtgg aaagtcagat agatgaattt acagatagta
    18721 caatagcaaa tcaacaacga ctacttgcta ataattatgt agagcttagt agagaggaaa
    18781 taagagagat atttgcaaat ctttattaat acaatttttt atttatatgt atagtcaaca
    18841 taaacaatgc taattatatt tatgtacaaa taaaaataag ggaacttaaa ttttaattaa
    18901 agttaagttc tcttattttt atatggagtt aaatataagt atatttttaa tttaaaatat
    18961 gcttatattt aagtctatta ctttatttga aacaatttgt agaatttcaa attccttgac
    19021 agtaataagt aagtaattgt ataatcaaac tgcaatatat taataatatt agtgaaaatg
    19081 aaaggattat aaaatatgta taaatcagaa aatttttcaa aaaaatctgt attaataaat
    19141 tcatttttaa gtaaattttt aaaaataatt ggatggggtt tggtaagctt atttacatta
    19201 tcagccttag tactttcaac tgtttccatt ataattggat gggctgtaat acttcctatt
    19261 caagtatgtg cagtattttt acttatagga ggagtttgta tttttaaagg taagagatta
    19321 ggagaccaaa tttctcgtta taaaaaatat tgtacaatta taaacaatag aaatattatt
    19381 ccagtagaac ttattgcaga aaacacatct aaatcattaa attttataat aaaagatgta
    19441 caaaagatga tagacaaaaa ctactttata aatacttata ttgataaaag aaataatcag
    19501 attgtgttaa caagtgaaga ttttgttcca ccaagatatg aagatgtagc atatgaagtc
    19561 aaagaagaag aaaagactga tgaatccaat gaagttgata caattataaa taaaggaatg
    19621 aattatctaa cacaaataaa agaagctaat aaaaatatta aatcagaatc aatgggcaat
    19681 aaaattgtac aagtagaaga tgttacaagt aaaatatttg atgttgtaaa acatgaccca
    19741 tcaaaactta ctcagataca aaaatttatg gattattatc ttccaaccac tttaaaacta
    19801 ttaaattcat atcatacatt ggaagaacaa ggaattgata gagaaaatat aacaacaact
    19861 atggaaagta ttgaaaatac aatgaatacg attgtagtag cttttgaaaa tcaattggac
    19921 tatctgtttg aagatgaagc cattgatatt tctacagata ttactgtttt agagaatatg
    19981 ttagtccaag aaggattaac gagtggtaaa ttttaacttc aatagaaaaa atattctgtt
    20041 atttttaaac aattaattag tcataaagta taaaatgtgt attatataag ttaatcagta
    20101 ctttatgaag gaagaggaga gaaagataca atgaataatt tagatgatat accagttatg
    20161 ccaactttga cacttgaccc atttggagaa gaatcaaaca ctaatgatat agataattct
    20221 gacttattaa tgaaaaagga tgaaaaagac ccagaagaag aaaaactgtc tgaatctgaa
    20281 cgcaagatgg taaaggaatt tgcggaaaaa atagatatta caaatacaaa tatgattttg
    20341 caatatggag ctggtgctca aaaaaaggta gcaagttttt ctgaaacagc tttaaagagt
    20401 gtaaagacaa gagatttagg agaagttgga gatatgctta caaatctagt tactgattta
    20461 aaagcatttt cagcagatga aaaagaacaa agtggttttt taggaatttt taaaaaggca
    20521 aataataaaa tttcaaattt aaaaactaag tatgatagtg cagaggtaaa tgtggataaa
    20581 gtaagcaaag agcttcaaaa gcatcaggtt aaaatattga aagatatagc aatgcttgat
    20641 aagatgtatg aattgaactt agcttactca aaagagctta ctatgtatat tatagcagga
    20701 aaacaaaaat taaaggatat gaaagaatat gagatgccaa agttgagaga aaaagctcgt
    20761 ttatctggtt caacagaaga tgctcaatct gtaaatgata tggtttcact ttgtgacaga
    20821 tttgaaaaga agattcatga cttagaatta actagaatgg tatcgcttca aatggctcct
    20881 cagataagat tggttcaaaa tagtaataat ctgatggcag aaaagattca atcaactata
    20941 gtaaatacca ttccattatg gaaaaatcaa atagtgcttg ctcttggaat ttctcactta
    21001 aatcaagcta tgaaagcaca gcgtgaagtt agtaatatga caaatgagct tttattaaag
    21061 aatgcagaaa ctttgaagat gggaacaata gaaacagcaa aagaatcaga aagaggaatt
    21121 gtagatatag acacaattaa gaaaacgaat caatctctaa tatctactat tgatgaggta
    21181 gttaaaatac aacatgatgg tagaataaag agacaagaag cagaagttga attatcaaaa
    21241 atagaaaatg aacttaaaag taagcttctt gaatttacag ttaaataaaa attatactaa
    21301 tataaaaaga gactgtctca aaatagagat aagtctcttt ttcattgttt aaatgattaa
    21361 agtatattta tattataaat ttctattatc ttttaacata acatcatgag ctccaccttc
    21421 aactatacta gtagaagata caagtgtaag tttagcattt ttttgaagtt caggaatgct
    21481 aagtgctcca cagttacaca tagtagaacg aactttactt aaagaaagag ttacattgtc
    21541 tttcaaagaa ccagcataag gcacataaga gtcaacacct tcttcaaaag aaagtttctt
    21601 atctccacca aggtcatatc tttgccagtt tctagcacga gcagaacctt ctccccaata
    21661 ctctttcata taactaccat ttatattaac tttgttagtt ggactctcat caaaacgaga
    21721 gaagtatcta ccaagcatta taaaatctgc acccatagct aaagctaaag ttatatgatg
    21781 gtcataaacg ataccaccat cagagcaaat tggaatataa atacctgttt tttcaaagta
    21841 ttcgtctcta gcttgagcaa cttcaattat agaagtagct tgtccacgtc ctataccttt
    21901 ttgttcacga gttatacata tagaaccacc accaatacca actttaacga agtcagcacc
    21961 agcttcagct aggtaaagga atccttcgcg gtcaactaca tttccagctc ctaccttaac
    22021 tgtatcacca tatttttcac gaatgaaatc aagtgttatt ttttgccact cagaaaaacc
    22081 ttctgaagaa tctatacata aaacatcagc accagcttca actaaagcag gaacacgttc
    22141 agcaaagtct ctagtattaa taccagctcc aactacatat ctcttagaag aatctaaaag
    22201 ttcaagtgga ttttctttat gagaagagta atctttacgg aataccatat acataagatt
    22261 accattatca tcaagtacag gaagagaatt aagtttgtgg tcccatataa tgttgtttgc
    22321 ttcctttaaa gtaacatctt tgttagcata aactatagat gacataggag tcataaattc
    22381 actaacttta gtatctaaat ccatacgact tatacgataa tcacgacttg caacaatacc
    22441 caataattta ccagttgaag ttccatcttc agtaacagct actgtagaat gtccagtttt
    22501 ttcttttaag tcaagtatgt cttttaatgt gttatcaggt ttaatatttg aatcacttac
    22561 aacaaaacca gctttgtggg atttaacacg tgctaccata gcagcttcat tttcaatagt
    22621 ttgagaaccg tatataaatg aaataccacc ttctttagca agtgcaatag ccattttgtc
    22681 atcagaaaca gattgcataa tagcagaagt caaaggtata ttcatataaa tatctgcttc
    22741 ctcgcccttt ttaaatttag taacaggtgt ttttaaactt acattagcag gtatacaatc
    22801 agtagaagag aaacctggta caagaaggta ttcactgaaa gtatgtgatg gtgtatcaaa
    22861 ataaaacgcc attttttaat cactccttat atttttatac tttttataat tgatagtatt
    22921 aattataact tattctttaa ttttattaaa gtattttgtc aaatattgag atttttgaaa
    22981 aatttaaact attttaatta aatttgttta atatatattg ccctataggg taaagttgta
    23041 tattaaataa tgtttagtgt ttaatagtag ctaatttaaa attaatcttt agtgattcat
    23101 ataattacat ttgtatagtt tacattgata atattactag agagtgcata aacctcaaaa
    23161 atacagataa attaaatcta tattagtata tccaaaagta catttaataa atttatttaa
    23221 ctgaattatt attttcattt ctattaaatt taaatatttt ataaaaatag tattatttac
    23281 aaaatcatat actccaaaat actacataaa taaaattaaa caaaaactaa aatgacaaat
    23341 gtcattatct aaagtgacat agaaacggtt tcttaaagtt gttactataa aatataaact
    23401 ctataataaa agtataacaa aagggaatca tatcgatata gaatataatt caagaggagg
    23461 taaaattatg agtagttcta atcaatcgac aataaagaca tctatacagc gagtagggaa
    23521 atttttaagt ggtatggtaa tgccaaatat aggagctttt atagcatggg gtcttataac
    23581 agcattattt ataccaacag gatggatgcc taatgaaaaa ttgagtacta taggtgaccc
    23641 aatgataaaa taccttttac cactattgat agcttatact ggtggtaaag caatagcagg
    23701 acaaagaggt ggcgtaatag gtgcagcagc agctatggga gtaattgttg gtgcagatat
    23761 accaatgttt atcggagcaa tgataatggg accatttgca ggatgggtaa ttaagaagtt
    23821 tgataaattt gtagatggaa agataccaac aggatttgaa atgttagtaa ataacttttc
    23881 aataggtata ataggtatgc ttcttgcaat actaggattt tatgcaattg gaccagcaat
    23941 agtagcaggg acagctctta tagaatctgg agttcaattt atagttagca aaagtttatt
    24001 gcctctagtt tcagtattta tagaacctgg aaaagtatta ttcttaaaca atgcaataaa
    24061 tcatggtata ttagggccta taggtatagc tgaggcaaaa gaagcaggta aatctataat
    24121 gttcttacta gaaagtaacc ctggaccagg tttaggagtt ctattagcat attggatgtt
    24181 tagtagagga agtgtaaaac aatcagcacc aggagctgta ataatacatt tctttggtgg
    24241 tatccatgaa atttacttcc catatatttt aatgaatcca gttttaatat tggctacaat
    24301 ggcaggtgga gcagcaggaa tattgacttt ttcaatatta ggagctgggc ttgtagcagc
    24361 accatcacca ggaagtatat ttgcacttat ggcactagct ccaaagggag gattacttcc
    24421 agtattagca ggagttgcag tggcaacagt tgtatcattc ttagtggcag caccatttgt
    24481 taagagagct tcagcaaatc aaagtgaaga agacagtact tctttagaag aagctaaagc
    24541 aaaaatgagt gatatgaaat ctgcaagtaa gaactctgag aaaaatattg aggaaaaaca
    24601 gcttgaagta aatgagatta agaagattgt atttgcatgt gatgcaggaa tgggttcgag
    24661 tgcaatggga gcttccagat ttaaaaatag aataaaaaac ttagacttaa atatagaaat
    24721 tacaaattca tctgttgata atcttccaga tgatacacaa atagtagtaa ctcacaatac
    24781 attagttgaa agagttgcta agaataattc aagtgttgag atagtttcaa taaacaattt
    24841 tttaaatgac ccaaatttag atgcattatt taaaagatta gaatctaaat aaaaataaaa
    24901 agtaccacta attaggagtg gataatttga aaaaaaagaa gattacatct aggcaaaaaa
    24961 agataatact aatgatagta gaaaattcaa agaaaaacat tccaataact atttctgaga
    25021 ttgcagggac tttagagtta agttcaagaa ctgtacttag agatatgtct ggaattgaaa
    25081 aatggtttga tgaaaatgat tttaactttg taaaaaaacc aggagtggga ttgattttag
    25141 aggaaaatat agaaaatcaa aactttataa ttgagttgtt agaagaagaa aaaatagaaa
    25201 aagaatacag caaagaagaa agaaatttaa ttatattatc aaagctacta gtttctaacg
    25261 agccagtaaa atcctattat tttgcaaaaa tattaaaggt atctgaaggg gtactgaata
    25321 atgattttgc cttagcaagt aaatggttgg aaagatttga tattgagctt gttagaaaac
    25381 cagggcttgg tgtctattta aaaggtcaag aaaaaagctt tagagaggca tatgtaaatc
    25441 ttatatacga ttcattcaat gaaaaagaaa tactagatat ggtcagaaat ataagtgaaa
    25501 atatacaaac agataaagca atagaaattt taagtgaaaa tagactttta aatttaatag
    25561 acaggtgcat aataagaaaa gttgaagcta cattaacaaa gaagctttca gatttagatg
    25621 taaatttagc tgatagtgca tatatagggc ttgtagttca tatttcatta gccttacaga
    25681 ggataaaaaa tggtgaaaat ataactatgg ataaagagtt tctaaaagaa ttatctataa
    25741 cagaagagtt taaattagct aaagaaatcg taaaaggtat ggaaacagat tttaacatgg
    25801 atataccagt agatgaggtt ggatatataa ctatgcatat aagaggtgca aagcaaaggt
    25861 catcttcaaa ccataaggct ttaaacttag atgatataga aataatggaa attacaaata
    25921 agatgataga tttggcggaa gatgaattta aaataagttt aaaaaatgac gagaggttat
    25981 ttaaagacct agcaaatcac ttagggcctt ctataaatag attgaatatg ggattagaaa
    26041 taagaaatcc tcttttagat gaaataaaaa gcaagtattc atatgcctat gatggagttg
    26101 aaaagatttc tagaattata aaagataaac taaatataaa ttcaatacct gaatcagaaa
    26161 taggatatat tgcaatgcac tttgcatcag ccatagaaaa aaatcttatg atgaatacta
    26221 atataaatat tgttgtggca tgtcccactg gaataggtac ttcaagattc ttatcaacta
    26281 agattgaaaa taaatttcct aatttaaata tacttgaaac catatcagct ataaacatag
    26341 atgaagagta tttaaaggaa aaagatgttg atttaatagt gtctacagtt gagttaaata
    26401 caagtttaaa ttatatatgt gtaggtccat ttatgagttt agatgatgaa cagataatca
    26461 aggaaaaaat aaaatctata gctcaaaata aattaatcaa tttaaatgcg aaaaatgata
    26521 ctaagagtaa gaataaagta tatgaacaga taacagaaag tatgaatata ggaaaagata
    26581 ttcttcaatt tttagaggaa attagatttg aaaaatttga aagtaaagat ttaagtgagc
    26641 ttattgaaga ctcatcaaaa atatttgcaa aatctagtga agatataatc tctataaaag
    26701 aatcgttaaa agaaagatta aaaatttcaa ttccatatat agaagaatca aaaattctat
    26761 tgttacattg tatgagtgaa agaatagata ttatgaagtt atcaataata aaactagaga
    26821 atagaatcgt gctagattca aatgaagaaa tcgacaatgt agtttttatg ttacttccta
    26881 aaaattcacc aagttatcaa agacaaataa tgagtgaaat aagtggttca ttaatagaca
    26941 atataatttt tactaataag ataaataaat tctctataga agagatggca ttagaggtaa
    27001 aagatatagt ttttaatttt tatacaaaca gattaaaagc atttatagat aaataaaatt
    27061 aatattaaaa aggaaggttg atactatgag taaagtattg aatgagaata atatattttt
    27121 agggttagat agtgtttcaa aggaagaagc tataacttta gcaggaagaa aattagttga
    27181 aaatggatat gtaaaagaag aatatatacc agcaatgtta gaaagagaaa aagtaatgac
    27241 tacatatatg ggaatgggag ttgctattcc acatggtgta aatgaagcaa aaaaagaaat
    27301 attatcttct ggaatagtta tattacaatt ccctaatggt atagattttg atggagaaaa
    27361 agcatattta ttaataggaa tagctggtgt tggagatgaa catttagaaa tactatctaa
    27421 tatagcagta gttttagatg atgacttaac agaaagacta aaaaattcaa atgacaaaca
    27481 agcttttatg gaagcttttg ccaactaatc ttaggaggga tttaaaatga aaaaggcaat
    27541 tcagtttgga gcaggaaata ttggaagagg ttttattgga ggcttgttag ttaagtcggg
    27601 ttatcatgta gtatttgctg atgtaaatga ggatatatta aactcaataa acaaagataa
    27661 aaagtatact atacacataa gagatgtaga atgtatagat gaagtaattg ataatataag
    27721 tgcggtttca tctataaaag aagaaataat agatgagatt gtacaggctg aaataataac
    27781 tacagcagtt ggacctttag ttttgactaa aatagcctct acaattgcaa aaggtataaa
    27841 ggctagaaaa gaaaagggat taacaagtaa tctaaatata atagcatgtg aaaatgcaat
    27901 atacgcaagt tcttctttaa aagaagaggt acttaagtat ttaaataagg aagaagtaga
    27961 atatttagag atgtatgttg gttttccaaa ctgttcagtt gatagaatag ttcctcctgg
    28021 taaaaacgaa aatcctcttg atgtaacagt tgaaaatttt tatgagtgga atgttgaaaa
    28081 acaaggattt aaaggggaaa taccaactat agttggaatg aatttagctg ataatcttat
    28141 ggcttatata gaacgtaaat tgtttacact gaatacaggt catgctataa cagcttatat
    28201 aggatattta aaaggatata agactataga agagagtata aaagataaat ttatctgtga
    28261 tatagtcaaa agtgcaatgg tagaaagtgg agaaggattg attaaaaaat acaattttga
    28321 ctcagaagtg cactataaat atattgataa aattttaaat agatttaaaa atccatatct
    28381 taatgatgat gtattaagag tcggaaggga accattaaga aaactaagtg ataaagatag
    28441 attgattaaa cctttaatga cagcaaaatc atatggatta tcagttgata atttgattct
    28501 tggaataggt gcagcgcttc attataataa tagtgaagat actcaaagtg tagaattaca
    28561 agagttgata aagtctattg gggtaaaaaa agccgttgct aaaatagcta atataagcaa
    28621 tgacgaagaa cttttaaata atatcgaaaa aagttatata tttatgaaaa atttataaat
    28681 ttacttgaaa aaaagtagtt ctgataaagt aactataata gattattcta cacagtttga
    28741 attatttgtt gaataataga gaattataat atataattaa aaggaataaa ttaatatatt
    28801 tacctgtata tgtttgataa tatggttcaa atgtttctac taagctacca ttaatagctt
    28861 gactacagga gtgaagaaga tatagtttat acttatttta aattatatat taagttaatt
    28921 actttgaatt ttaagctcct gtctatgata tagacaggag cttttttagt attttaatat
    28981 aaaatactta caagaataga tagcaaaatt agaacaaata taattttttt attaatataa
    29041 ttttagaaag ggctaggtgg aagttcaatg aaggctttac aagaaaagat attgagagaa
    29101 ggcagtgttt caggaaatga tatactaaaa gttgatagtt ttttaaacca tcaaattgat
    29161 gtagcttttt taaatgaaat aggaagagaa tttaaagaga gatttaaagg agaaaaggtg
    29221 gataagatat ttacaataga ggcttcagga atagctatag catcaattgt ttcacagtat
    29281 tttgataatg cacctgtagt atttgcaaaa aaatcagaat ctaaaaattt ggataaagat
    29341 gtatatgaaa ctaatgtata ttcatttact aaggcaagag agtattcagt taaagtttct
    29401 aaaaagtaca taaacaaagg cgaaaatata ttgatagtgg atgatttttt ggcaaatgga
    29461 agagctgctc ttggacttaa agatttaatt gagcaagcag aagctaactt agttggagta
    29521 ggaattgtca ttgaaaaagg atttcaagct ggaggagcac ttttaaaggc taatgatgta
    29581 agattagagt ctttggcagt agttgaatct atagataatg gaactgtaaa atttaggtaa
    29641 tttatgatat tatatacttg tgtttagcac atattttaac tatgtaatta tggaggattt
    29701 tttatgagat tttttataga cacagccaat attgaagaaa taaaagaagc aaatgattta
    29761 ggtgtaatct gtggtgtaac tactaatccg tctctaatag ctaaagaagg tagagatttt
    29821 atagaggtag ttaaagaaat aagtgaaata gtagatggac caataagtgc agaagtaata
    29881 agtttagaac ataaaggtat gatagaggaa gcagaaaaat tatctaagat acataaaaat
    29941 atagttataa agatacctat gacagcagaa ggtctaaaag cggtgaaagt actatcaagt
    30001 aaaggtataa agactaatgt aacacttata ttctctgctg gacaagctct tttagctgct
    30061 agagctggag ctacatatgt aagtcctttt gttggtagat tggatgatat atcacaaaat
    30121 ggtcttgatt taattgaaga aatcgttgat atatttagtg taaatagtat tgaggctcaa
    30181 ataatagttg ctagtgttag aaatccaata catgttttac aagctgctag aatgggagca
    30241 gatatagcaa cagttcctct taaagttata aaccaaatga ttaagcatcc tttgacagac
    30301 aaaggaatag atagctttat gaaggattgg gaaggtgctt ctttaaaatt ataattataa
    30361 actacgcttt ataagtatat taaagaggtt attatggaaa ttctaagtaa taaggctagg
    30421 ctattttgcc tagtcttatt ttggtgtata atatattgaa acatattatt gaaatagatt
    30481 aattttttaa gtgaggaggc gaaaaatgga taaaatatta agagagatac aaagagaaga
    30541 taaaaaaaat ccatatactg accaagaact tgctgaaatg ttaaatgtag ctaggtctga
    30601 agtgatatca gttaggaaaa aaaataatat tttagattcg agagaaagaa gaaaaaaaat
    30661 attaataaaa gatatatcaa aaattgtaag tgaaaatcct caaatgtctg aaagaaaaat
    30721 aactgaaata ttaatagaaa atggatataa tatatcgaga agtgcagttt caaaattatt
    30781 aaaagaggaa aatttaaatc agtcaaagat tgggattaag gataaagacc cagcatcatc
    30841 aggaaagtat gtgaaggtga gtaaagttgt agaagaagat ggatttgaag aattgatagg
    30901 tataaaggga agtttgaaag aaaaggtaaa tctagctaag tcagcaataa tgtatcctcc
    30961 taatggcctt catactataa tatatggaga aacaggagta ggtaaaagtg aattagctac
    31021 atgtatgtat aaatatgcta taaaaaacaa cattaaagaa gagaacagcc catttatagt
    31081 gtttaactgt gcagactatg cagaaaatcc taatctattg atagctcaac tctttggggt
    31141 agtaaaaggt gcatatacag gagcagatgc aaatagagaa ggtcttgtag aacaagctaa
    31201 taatggaata ttgtttttag atgaaattca tagattgcct gctgctgggc aagaaatctt
    31261 attttcatta atagatagag gagaatttag aaggttagga gaaagtagtt ctaatagaaa
    31321 ggcaaatgtt ctcataataa gtgctacaac agaaaatcca gattctaatt tacttcaaac
    31381 atttagaaga cgtataccaa tggtaataaa tttacctaat atgagtgaaa gaccaaaatc
    31441 tgaaagatat gaaataataa taaagttttt tgaaagagaa gcaaagcgag taaacaagaa
    31501 ttttataata actaaagaag ttatgtgtgc acttatgaat tataagtgta ctggaaatat
    31561 aggtcagtta aagagtgata tacaagtaac ttgtgctaga gcttttagta aatcgatatt
    31621 ttctagcgat aaagtaatta tagatttaga tagtttaagg gattatataa aaagtggata
    31681 ttatgattgt aattgtaaaa atgaaaagta ttctgagttt tcagttgagg atatatatat
    31741 agatattagt gaattggtga gtggaaaaaa tagaatttta tctgataatg agataagcga
    31801 gatatataat tatgcagaaa aagagcttaa ggttttggaa agtaagtgct tttcagaaga
    31861 agagttaaaa aatgcattta tagaaaagtt agataagaag tttaatgcta ttaaaaacaa
    31921 taaaaattta tctgatagaa gaagtcgaat agactgggga ggacaattaa aagagtctac
    31981 actggagata atggataagg taattgtatt tattaaggag cagtttaagc atgtaaatca
    32041 aggtctgtac ttggctctag caattcatat tgagcatgct ataggtagga taaaagatgg
    32101 aaaaactata ataaatccga gtttagataa aataaaagca tcaatgccaa tggaatatga
    32161 gttgtcaaga tatataatgg gtatagtaga agatttgaca caagtaacat ttccagaaga
    32221 tgagcttgga tatttggctt attatataaa taaattttgt tataatgagg aaagtataaa
    32281 agataaagtt aaagtagtaa tagttacgca tggtaaagtt ggaattgaaa tgtctaaagt
    32341 tgtaaatcat attttaggta tagaatgtac actaggtata gaaatagcac ttacagattc
    32401 accatcagag gggatagagc atgtattaga agagcttcaa aagatagaag ctagaaaagg
    32461 tattctagtt ctaattgata tgggttcttt ggtaattctt ggtgatgagg ttgaaaaaag
    32521 gcttggaatt agatgtaaaa ctgtaaatag agtagataca ttattggcaa tggaagcagg
    32581 aaaacttgca actattgaag gaaaaagttt agatggtata atagctgatt taaagaaaaa
    32641 taagaattat gctatgataa atacaaataa atttagttac agaaaaaacg agtatggaaa
    32701 gaaaaatgta atcattactt tatgtttgag tggtgtaggt acagctttaa atttaaaaga
    32761 gcatatagaa aaacaaatta aggaatatga cactttaatt gaagtaaagc cagttgcttt
    32821 tttaaataat aatttagaag aagagttaaa tgatattgaa gctgaatata atattattgc
    32881 tatctgtgga actattgata tagattataa aaacgtgcct tttatttctt ataatgaggt
    32941 acttggtaaa aatggtatta ataaagtatt agagcattta aatagtaaac aaccagcttt
    33001 aaatattgaa aaccagttga ataatttaat acatgaagat ttgattttat acaattttga
    33061 aggaatttca aaggagtata taattgatac tcttgtttca aaacttgaag aaggtggata
    33121 tgtcgactca aagtatatat taagtgtata taaaagagaa gcaatgggaa gtgttgtaat
    33181 ggcctctaag gtagccgtgc cacatggact tccagaaaac gttataaagc ctgcaatagc
    33241 aatcgcgagg ttgaataaac ctatagtatg ggacaataaa tttatggtgg atttggtggt
    33301 actactggca cttaaagaaa ataataagaa agaaatacga agcttatttt caaagattaa
    33361 tgaccagcat actttagaag ttttattaaa tactgaagat aaaaatgaaa taaaagaact
    33421 tttaagataa ttgttagtac cgagaagaaa gacaaaaaaa tttgctttag tataaaattt
    33481 aaaactactc aattgctaag tagttaatta ctctatataa ggctagttct atgaaattta
    33541 tttatatgat tttatagaat tagctttttt cttggtaaat aaaatatatg aatttattta
    33601 tgtaaaaagt aaattttatt ggacaattct atgagaattt ttcctat
//
LOCUS       DAEPUT010000041        32526 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.042, whole genome shotgun sequence.
ACCESSION   DAEPUT010000041 DAEPUT010000000
VERSION     DAEPUT010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32526
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.042"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            178..846
                     /locus_tag="KRL22_002107"
     CDS             178..846
                     /locus_tag="KRL22_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272596.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            848..1333
                     /locus_tag="KRL22_002108"
     CDS             848..1333
                     /locus_tag="KRL22_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBH1272597.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            1394..2515
                     /locus_tag="KRL22_002109"
     CDS             1394..2515
                     /locus_tag="KRL22_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HBH1272598.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTVVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            2796..3986
                     /locus_tag="KRL22_002110"
     CDS             2796..3986
                     /locus_tag="KRL22_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1272599.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    4120..4375
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4434..5435
                     /locus_tag="KRL22_002111"
     CDS             4434..5435
                     /locus_tag="KRL22_002111"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBH1272600.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            5539..5928
                     /locus_tag="KRL22_002112"
     CDS             5539..5928
                     /locus_tag="KRL22_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HBH1272601.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            6089..7297
                     /locus_tag="KRL22_002113"
     CDS             6089..7297
                     /locus_tag="KRL22_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBH1272602.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(7383..8459)
                     /locus_tag="KRL22_002114"
     CDS             complement(7383..8459)
                     /locus_tag="KRL22_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1272603.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            8688..9215
                     /gene="hpt"
                     /locus_tag="KRL22_002115"
     CDS             8688..9215
                     /gene="hpt"
                     /locus_tag="KRL22_002115"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH1272604.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            9304..10236
                     /locus_tag="KRL22_002116"
     CDS             9304..10236
                     /locus_tag="KRL22_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBH1272605.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIAAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            10298..11524
                     /locus_tag="KRL22_002117"
     CDS             10298..11524
                     /locus_tag="KRL22_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1272606.1"
                     /translation="MKKIVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTRFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            11608..11829
                     /locus_tag="KRL22_002118"
     CDS             11608..11829
                     /locus_tag="KRL22_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH1272607.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            12018..12188
                     /locus_tag="KRL22_002119"
     CDS             12018..12188
                     /locus_tag="KRL22_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272608.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(12281..12742)
                     /locus_tag="KRL22_002120"
     CDS             complement(12281..12742)
                     /locus_tag="KRL22_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272609.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            12925..13392
                     /locus_tag="KRL22_002121"
     CDS             12925..13392
                     /locus_tag="KRL22_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272610.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            13435..15198
                     /locus_tag="KRL22_002122"
     CDS             13435..15198
                     /locus_tag="KRL22_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HBH1272611.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            15206..15814
                     /locus_tag="KRL22_002123"
     CDS             15206..15814
                     /locus_tag="KRL22_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1272612.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            15886..16455
                     /locus_tag="KRL22_002124"
     CDS             15886..16455
                     /locus_tag="KRL22_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBH1272613.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            16973..20512
                     /gene="nifJ"
                     /locus_tag="KRL22_002125"
     CDS             16973..20512
                     /gene="nifJ"
                     /locus_tag="KRL22_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBH1272614.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMIELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(20903..21829)
                     /locus_tag="KRL22_002126"
     CDS             complement(20903..21829)
                     /locus_tag="KRL22_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HBH1272615.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPNNNKPESNKPEDNNNSGSTDKPDNNKPESNKPEDN
                     NNSDSTNKPDDNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKK
                     SQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGH
                     RKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(22325..23659)
                     /locus_tag="KRL22_002127"
     CDS             complement(22325..23659)
                     /locus_tag="KRL22_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1272616.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            complement(23721..24497)
                     /locus_tag="KRL22_002128"
     CDS             complement(23721..24497)
                     /locus_tag="KRL22_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH1272617.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITKLQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            24839..27883
                     /locus_tag="KRL22_002129"
     CDS             24839..27883
                     /locus_tag="KRL22_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH1272618.1"
                     /translation="MKKILKRLATGFLAFATIVTALPTTAVHASEKQYWTESAERVGI
                     VEKVMNDGSIGSTFNEGHMTVEGEDAFCVDINTNFKNGYKTRADASTRMSYDQISDVA
                     LSIEYVNQYVQSHSGLSSQHIYLLKQCVVWQRLSVHLGWQCDNVRASYDEIPKAIQDE
                     VYAGAKAFASENKGRYECGGYIYSGEGQDIGQFWAKLAVGNATLKKTSSNASITDGNG
                     LYSIAGATYGIYSDKDCTKQLATLTTDNSGNTDTVEVKAGTVYIKELSAPAGYKVDST
                     VYSLNVEAGKTATLNVSDTPKVTDTLIELFKIDMETQKDAPQGDASLEGAEFTWKFYA
                     GHYTADNLPSEPTKTWVTKTIAEKDSDGTIHYVSRLSDEYKVSGDSFYTQDDKNVLPL
                     GTLTVEETKAPNGYLLDGAYMQANGSEEQIKGMYLTQITEDGDIAVLSGSNQYHVSDK
                     VIRGGVKIQKRDLETSDTKGQGSATLKDAEFEIISLNDNAVLVEGKLYNKGEVVKTIL
                     TDIEGVASTSADLLPYGKYRIEESKAPEGYLTDGAEPIEFEITEDGKIVDLTGTDTSI
                     YNQVKRGDLEGVKIGAGTHQRLAGVPFRITSKTTGESHIIVTDDNGQFSTSSDWASHK
                     HNTNAGKTSEDGIWFGTSEPDDSKGALIYDTYIIEELRCEGNKGFELIPPFEIVVSRN
                     NVTVDLGTLTDEYEKEITIHTTATGKDGEKSIVAGKEVTIIDTVTLDGLEKGTKYQLK
                     GWQMIKDENAELLIDGQRVENDYTFTADSEEMKIEMEYTFNASSLGGQNLVTFEELYD
                     LSNEDEPVKVAEHKDIDDEGQTVLITERIISIHTTATSEDGKKEIEAGKDVTIIDTVT
                     LDGLEIGTKYQLVGWQMIKDENAELIINGERVENDYTFTADSESMEVQIAFTFDASEL
                     GGKELVTFEELYDLSNPDEPTKVTEHKDIEDDGQTVTITEVPETPEEPTEPEQPTTPD
                     TPSKTTDAPKTGDNTNIALFLGLLVLSGAGVAGTYFFKRRRS"
     gene            28077..28403
                     /locus_tag="KRL22_002130"
     CDS             28077..28403
                     /locus_tag="KRL22_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1272619.1"
                     /translation="MKLKYIVPDMAQTFGNLEFAGENDVEQQRVNGRFVPVTRSYNLY
                     SDIQRADDIIVVLPAKAGEKRFKYEQKVKLVNPKITAEGKNVRGRGYTNYILNADDML
                     PVEESK"
     gene            28419..28805
                     /locus_tag="KRL22_002131"
     CDS             28419..28805
                     /locus_tag="KRL22_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1272620.1"
                     /translation="MRLANGIVLDKEKTFGVLKFSALRHEVRVENEDGTTTEEIKRRT
                     YDLKCSQQERTIQVSIPAEIPVKDYPYNAEVELINPVADTVANANYRGADVEWYIKAD
                     DIVLKNKGGQPAGNPQNHVPQGQQKK"
     gene            28979..29494
                     /locus_tag="KRL22_002132"
     CDS             28979..29494
                     /locus_tag="KRL22_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008370126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272621.1"
                     /translation="MLNENIRTLRKAKGLSQEELAIKINVVRQTVSKWEKGLSVPDSS
                     MLVSLAEELDTSVSTLLGETVQEECLNEGDLKSISEKLEVINLQFAKKSERKIKTIRY
                     SLILVCVFIAVVFIALVTMNSEYLAWDFNNPELAIVGTLLHGFEFLFVRLAPFVFIGS
                     VIGIVLTYRKR"
     gene            29569..30963
                     /locus_tag="KRL22_002133"
     CDS             29569..30963
                     /locus_tag="KRL22_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008792582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1272622.1"
                     /translation="MNILKYKGKRIRASDKNLVYRFCAGTLLLLFVAVLLLLNMGQLM
                     RTDWEHFSLLDNGLTLSTYNFITILIATGVCALVAFLYYRFFHDSFKKLLHRQKLARM
                     VLDNKWYEAQTVQDSGFFTDLQSRSREKIVWFPKIYYQMDTGLLHIRCEISLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVKAENGGLRLMKNLT
                     WEYDALPHALICGGTGGGKTYFLLTIIEALLQTNAQLYILDPKNADLADLGTVMDNVY
                     HTKEDMIECVNAFYEGMVQRSEEMKHHPDYKTGENYAYLGLPPCFLIFDEYVAFLEML
                     GTKESISLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRENFNFRVGLGRISEL
                     GYDMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQAIGSLVLTRQ
                     DGTATCEAKGDGTD"
     gene            31164..32354
                     /locus_tag="KRL22_002134"
     CDS             31164..32354
                     /locus_tag="KRL22_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBH1272623.1"
                     /translation="MNESTFITALKEKRLSYGVSQTRLAIMAGISREHLNRIEAGKVK
                     LTDDMQDKLMEAVEKFNPDAPMFLLFDYVRIRFPTLDIQHVIRDILKLNVDYMLHEDY
                     GHYKYTEHYYLGDVFVYTSRDEEKGTLLELKGKGCRQFESYLLAQGRSWYDFLMDALV
                     EGGVMKRLDLAINDRAGILDIPDLTAKCNREECVSLFRSFKSYASGELVKHNEQDKAG
                     MGHTLYIGSLKSEVYFCCYEKNYEQYAKLGIPIEEAPIKNRFEIRLKDERAYYAVREL
                     LTYYDAEQTAFSIINHYIRFVDREPEKRKTDWKLNDRWAWFIGKDRPPVKLTTDPEPY
                     TLERTLGWISRQVAPTLKMLKKIDAGNSTSYLKEIEDNAKLTEKHLQIIRQQTADTEE
                     LITE"
     gene            32370..32510
                     /locus_tag="KRL22_002135"
     CDS             32370..32510
                     /locus_tag="KRL22_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH1272624.1"
                     /translation="MAELVKDLVLVSLGMGIGVVLMCIAQVSKMADEEMEEIKKERID
                     KE"
BASE COUNT        11682 a         4520 c         6263 g        10061 t
ORIGIN      
        1 aaaaaaatat tatattttta aacttgaaaa gtaagtaatt ataagctatt taatcactgg
       61 aataaattta caataaaaaa ataaatacaa aggctttatc attaaggtat tggcataagt
      121 tttgcttatt aaacaagtat actaataaaa ttcatttaaa caggagggag aatttatatg
      181 agtaaattag aatcaacaac agaaaaagtt gaggtaaaat ggtatgggta tgtagcatta
      241 atattgggag cattattttt ttcaggaata tttaaagatg caccaggacc attaaaagta
      301 ttggatttta acaatgtatt aggttctttt ggaacattgg gaacaattaa tgatggtgta
      361 ggtacattag ctgcaaactt tagaggtgat ggaggtactg gccctcgaga tggatggcta
      421 tatgcattga cattaatacc atcagttatg tttgcacttg gagtagttag agttatagac
      481 cacttagatg gaatgaaggc agctcaaaag cttcttagtc cactattaaa gccattatta
      541 gggttacctg gatttgcagg actaactttg atagctagtt tacagtctac agatgcagct
      601 gcatctatga ctaaagaact taaagatgat gggtatatag atgaaaaaca aaaagctgta
      661 ttttgtgcat ttcaattttc aggtgcgtct gcaattacga atttctttgc ttctggagca
      721 gcactatttc catttatagg agatgtacca atatttatac cacttgcttt aatattaatt
      781 atgaagtttg ttggggcgaa cttacttaga ttatatttaa ataaatttga caagggggaa
      841 gcttaacatg agtgaggtag caaaaaaaga agtaaaagtt aaaaaaggaa atgtgataga
      901 tgcgtttatt ggaggagcta gaaatggatt ccaaataagt acaaattcaa tggctccaaa
      961 tgtcatcttc ggttttgcta taatttctgt gttcaactta acaggtcttt tggatgtaat
     1021 agggacaata tttacacctg taatgagtat ctttggactt ccaggtgttg cagcaacagc
     1081 tataatgaca atatttatat caatgggagg agcatctgga gtaatcgcag gtttatttac
     1141 agcaggtcaa ataagtcaag cacatgttgc aattctattg ccaatgttat tgctttcagg
     1201 agcgcagata caatttatgg ggagactttt aggaacagct gagttaaaaa ctaaatatta
     1261 tccacatatg tttgttatag caactttaaa tggttgtatt gcaatgctta taatgaatta
     1321 tttcgtagta taggtaatta taataaaaat ttaatataaa tggaaagttt aaattttaag
     1381 gaggagctag attatgggaa ctaacaaaga ttatattgag tatgtacata aagtgtatga
     1441 ttatctacac actataccag aaaaaggatt tgaagaatat aagacatcag agtttgtttt
     1501 aaaagagctt gaaaaaatgg ggtttgaaaa tattaataaa ggagttgcag gaactggtat
     1561 tatagtaact atagattcta aaaaagaagg accagtattt gctataagag cagatatgga
     1621 tgcattggaa tttatcatag atggagaaaa gaaaatgata catgcttgtg gtcatgatgg
     1681 tcatacttct atgcttttaa cagctgcaaa gttaataaaa gagagaaatt tagtaaaaag
     1741 aggtaagtta aaaatacttt ttcaaccagg tgaagaaaaa ttatatggag cattaagagt
     1801 aattgattct ggtttgttgg atgatgtaga agaaatggta gggatgcatt taagacctgg
     1861 acaagattgt aggttgggaa aggcgatacc tgcaatgtac cattgtgcta gctgtataat
     1921 ggaatttacg attaaaggta tcacttgtca tggttctaaa ccacatttag gagtaaatgc
     1981 agtagatgct gtctgtttag cagtgaatgc aataaatgca ataagagtaa atccagctat
     2041 accaaattct ataaaagtaa caaatatatc agttaaggga gaaacttata ataatatacc
     2101 agatgaagca tttatggctt tagatataag ggcagaaagt aatgatataa tagaagaatt
     2161 aaaagaaaaa gcaatacatg ctgtaaaaac tgttgtaagt tctataaatg cagaagctgt
     2221 actaatttcc aaagatggag taccagcagc agaatttgat gaagaacttg taaacttggc
     2281 tgaagaaact ataaaagatg tattgggagc tgatgcatct ataggtatat ttaaaaattc
     2341 tggtggagaa gacttccatt attatacaca aaaactaaaa tgtaaaacta catatattgg
     2401 attaggagct gatgctacac caggatttca taatccaaat gtaacatttg atacgaaagc
     2461 tttagaatat ggtgtagata tatggtgtag attggttgaa aagagattgg gataacatcc
     2521 aaactaataa ttctacattt aaaattataa ttatagaagt tatagaaaaa gattgcttat
     2581 gttaattaga aaataattaa tatgagcaat cttattttga tataatgaaa ctgattttgg
     2641 aatattgaaa aaatatgatg gaaaagtaat tatattttaa atctattgga caaaaaagtg
     2701 atattattat aatattaaga attgtaaaat aataccaaag tgcatctagt aatagactta
     2761 acaattataa aaattttatt cttaggaggg aaaaaatgag taagtataat tttgacagag
     2821 taatagatag agtaggaaca gattgtgtaa aatgggattt tagaactaat tgttcaacaa
     2881 aagcacaaaa agatggtttg cctttttgga ttgctgatat ggattttgaa tgtgcagaac
     2941 caataataga agcattacgt aaaaaagttg aacataaaat atttggatat agttcaaatg
     3001 atagtgataa atactttaat gcagtttgtg attggtataa aaggagattt aactgggaaa
     3061 taaatagaaa agatattatt tttagtcctg gtgttgtacc tgctgttgct attttagtaa
     3121 gaatattaac taattctaat gaaggtgtaa tagtccaaaa accagtgtat tacccatttg
     3181 aagctaagat aaagagcaat aatagggacg ttgtaaacaa tcctctaata tatgagaatg
     3241 gtacttatag gatggattat gatgatttag aagaaaaagc taagtgtagc aacaataaag
     3301 tactaatact ttgtagtcct cacaaccctg ttggaagagt ttggagagaa gatgaattaa
     3361 aaaaggttgt agaaatatgt aaaaaatatg acctatggat aatagctgat gagatacatt
     3421 ctgatttaat tagaaaagga tttaaacata ctcctttaca gtcattatgc ccagagtaca
     3481 aggataaaat agttacatgt atagctccaa gtaaaacatt taatctggca ggaatgcagt
     3541 tgtctaatat aatagtgaat aatgatgaac taaaaaagaa atatcaagaa gaggttacag
     3601 ctgttggagt tgcaacttca ccaaatccct ttgctattgt agctacaata gcagcatata
     3661 atgaaagtga agactggctt aatgaattaa atgattactt agataataat atacaattta
     3721 ttgatgaata cttaaaagaa aacctaccaa aagtaaaact tgtttatcca gaaggaacat
     3781 atctagcatg gttagatttt actgcttatg gattaaatga agtagaactt gaagatttaa
     3841 tgtttaaaaa agctaatgta ttatttgatg aaggttatat atttggaaaa gaaggaatag
     3901 gatttgaaag aataaatgta gcttgtccac agtctttatt aaaagaatgt atggacagat
     3961 taaagactat atttgaaaat ttataaagta taggtaaaaa tttataaagt gtttaaaaat
     4021 aaaaaaataa taaacttgac aaattttaac taatcactta tcatactatt atgaataaat
     4081 agaaaacata agagagctaa attttattga attaaactct taaagacttt gaaaggaaga
     4141 gtagttatag aatgtaatta aagcgagttg gtgatggtgt gagaccaata tgaagtctat
     4201 aatgaagaac atcctggagt tgctaaccga aattttaaaa gagtaggctt agtcggaacc
     4261 aaaccgttat catattgggg tgtatcgagt aatatctgta cattgtgagc tgggtttgaa
     4321 tttatttcaa actaatcagg gtggtaccgc ggaaaagcaa cctttcgtcc cttttatata
     4381 gggatgaagg gtttttttaa tggaaaaata tataaatata gggagtgaat gatatgagca
     4441 caataatacc aaaggattat aaaagtagtt tgaacgtaat tgatacacaa atagctataa
     4501 aaaaattaaa agattttttt gaaatgagac taagtaatga attaaatctt ataagagttt
     4561 cttctccgtt atttgtattg ccagaaacag gtgcaaatga taatttaaat ggagaaaagg
     4621 ctgtaagctt tgatatacca tttatgaata aaaatgcaga aattgttcaa tcacttgcaa
     4681 aatggaaaag attagccctt aaaaaatatg ggtttgaagt tggtagtggt ttatatacag
     4741 atatgaatgc aataagaaaa aatgaagaat tagacaatat acattctctt tatgtagacc
     4801 aatgggattg ggaattggtt atagataaaa gtagtagaaa tgaaaagact ctaaaagatg
     4861 ttgtaaaaag attgtatgga gtatttaaag atactgaaat ttttgtatgt agtatgtatg
     4921 aaggtataaa agaaatatta ccagaagaaa taacttttat aacatcacaa gagttagaag
     4981 atatgtatcc agaattatca ccaaaggaaa gagaagataa aattgtaaaa gagaagaaag
     5041 cagtatttat aactcaaata ggaaaaacat taatatcagg agaaaaacat gatggaagaa
     5101 gtcctgatta tgatgattgg gaattgaatg gggatatatt attttacaat cctgttttag
     5161 attcagcatt agaattatct tcaatgggaa ttagagttga tgaagaatct cttgatagac
     5221 aattgaaact tgctggatgt gaagagagaa aagagtttga ctatcataag atgcttttaa
     5281 atggcgaact tccgtataca attggtggag gaattggtca gtcaagaata tgtatgtatt
     5341 tcttacaaaa agctcatata ggagaagtac aagttggagt atggccacag gatatgattc
     5401 aaaattgtag tagtgcagga attgaattat tataatttaa atataaacta attgataaaa
     5461 tttatatcta atatgttcat caaattaatt atatcggtta taatgtagaa taacctataa
     5521 ttataagagg tgataaatat ggagttttta aaaataatca ttaatatagt tttagatatt
     5581 ttaaaaaaaa ttttggtcag atttaaaaat gctaaatttg gtttggtttt tgtatttgat
     5641 ttacttaaac tacctgattt tatgacagat aaaagaatca atatagttga taaaataaag
     5701 gtaatttctg tattaatttt tactatatcc tactttgtat ctggggttga tataattcca
     5761 gagatgattg caggggcatt tggttttata gatgatgcta tagttttaat ttggagtata
     5821 ggtatagtga atgaagaaat taataagtat agagttatcg caaaaaaaga taaacattca
     5881 aatataattg aaaatgtaga attttctata aaagatgaag aagaataaca atttatatat
     5941 gttattcttt tttttattaa caaaaaatgg ttaaattgtt gacggagagg taaaactcta
     6001 ttatcataat aagtggatat ccaatattta actaagtatt caatgtgcaa gaatgcttaa
     6061 tttaaaaaag ttatggaggg taaatattat gaagaaaaaa ataggtttag tgcccaaact
     6121 aatcatcggt atcatagtcg gtattttaat cggaagttat gcaccagaaa taatagtaca
     6181 aatattagta acagttagta ctttattctc agcattccta aaatttgtta taccatttat
     6241 aattataggt tttgtaacag caggtatagc tgatttagca acaggtgcag gaaagttatt
     6301 ggggataact acgggaatag catatggttc taccttaata gcaggattat tatcatttgc
     6361 agtatctaca ttaatcttcc caaattttat tgatgcaagt gttgcaagtc aaattggaga
     6421 cccagaggca ggaatgttag ctccaatatt cacaattcca ttagagccta tggtagatgt
     6481 aacagctgca atcgtatttg catttgtaat gggacttgga atatcagctt taagaaatca
     6541 tggaaaagga gagactttat ttaatttctt ccaagaattt caaggaatcg taacgaaaac
     6601 gttgtcaaca gtgattatac ctttattacc tttatacata gcaggaactt ttgcaaatat
     6661 aactatagca ggggaagtat ggacaatatt aggggtattc tggaaagtat acttagtagt
     6721 aataccttta cattttgtat atatggcatg tcaattcaca gcagcaggtg tattttcagg
     6781 aaaaaatcca gtaagaatgt taaaaaatca agtacctgga tatttaacag ctataggaac
     6841 tcaatcttca gcagcaacta taccagttaa tgttggttgt gcagaaaaaa atggagtaag
     6901 taagcaaata agagaatttg ttgtacctct ttgtgcaaca atacatttat caggtagtat
     6961 gatatcaata acaggattta caactgcagt tttaatgatg aatggtatgc cacatggaat
     7021 aggtgtatta ttcccttata ttgcaatgtt aggtatagca atggttgcag caccaggagc
     7081 accaggtggg gctataatga gtgcacttcc tttcctacca atggttggaa taccatcaga
     7141 tggtgggctt gcaagtttaa tgatagcttt atacttaact caagacagtt ttggtacagc
     7201 atgtaatgta tcaggagata atgcaatagc agtagtagta gataaaataa atgatggaat
     7261 gagtaaaaaa ggaaacaaag aagagcaaag tgcttagttt tttaataatc aaaaatgagt
     7321 tatctcaaat agagatagct cattttttat ggtataaaaa attataaaat aaagtgattt
     7381 ttttatttaa aaattgcttt aagagatgat attaataatt tattttcatt aggttttaat
     7441 atacatactc taaagaaata ctcatctaga ccttcaaatg aacaacaatc tcttattatt
     7501 attttttgtg ggagcagttg ctctcgaaga gatttagcag tcaattcctt tgtcttgatt
     7561 ttacacaata tgaaattacc tttagtattg tatatatcta agctttttat attcttaagc
     7621 tctttaagca ggtaatctct ttcagtgttc attaaggaaa tagtatttga tataaaatct
     7681 aaatcactaa acatgatttc acccatttta gaagctatta tgtttatatt ccataaatct
     7741 agatttttat ttatttcatt tttgacatta gtgttagata taagaccata tccaagcctt
     7801 attccaggcg ttgaaaaaaa ttttgatgta cctcttataa cgaataaatt agaataatca
     7861 tcaactaatt gagtacaaga gtatgtatct gtatcagtaa actctacata agtctcatca
     7921 atcattaaaa atgagtctgt attttttaaa atttctctca cttctacctt agtaaatgca
     7981 aatccagttg gattactagg attacagatt actaccaaat cataatcttt agcattgatg
     8041 gtttttataa gattttctaa atttatatga aaattatctt cttcttttgc aaagtatttt
     8101 tctatagaac aattaatttt agataactct ttttcatact ctgaataggc tggagagagt
     8161 aaaagagctt gtttaggatt aattgtatgt ataaatgatg aaattagttc tgtagctcca
     8221 ctgccaagta ctatattatc tatagaacat ttgcagtaat tggatataga agtttttaag
     8281 tctatgtaat cagggtcagg atacatagat accatatcta tattgtttac aatgtattgt
     8341 ttggctaaac ttgatgtacc aaaaggattt atatttgagc taaaatccat aaattcttcc
     8401 tttgaaaagc catacttact agataaacta tataaattag ctccatggtt tgtgctcata
     8461 aaagtacctc caaaaataaa attatataat cgataaaaat aactgattaa tatatgtaca
     8521 tatagattat aatacaaagg aatcgttatt ccaaattttt aatgtaaaaa gcaaaaaagt
     8581 atggataagc tgttaattta ggtttaaaaa tgatgaaaaa gattttaatt gatattttgg
     8641 tatgctataa tatataagtt aatagaagga aagcgggagg atacaaaatg tacaaagtta
     8701 caggaaaaat gttgacagaa gaacaaataa aagaaaaagt ttatgaatta ggaaaaaaga
     8761 tagaagaaga ctttaaaggc gaagatttac tagtggtagg tatacttaaa ggagctagtg
     8821 tatttgtttc agatttaata agatgtatag atttggatgt aaatatagat tttatgagtg
     8881 ttacaagtta tggaaactca acagagtctt ctggaacagt taaaatatta aaagatttag
     8941 atgtagatat tgaaggaaag aatgtgttga ttgtagagga tataatagat tctggtttaa
     9001 cattaagtaa tctagttgca gctttaaaaa ctagaaatcc aaaatcttta aaactatgta
     9061 ctctacttga caaacctcag agaagaaaag ctaatatacc tgtagactat gttggatttg
     9121 ttatagaaga caaatttatt gttggttatg gaatagacta tgctgaaaag tatagaaatt
     9181 taccttatat aggtatagtt gaggatgtag aatagattta aatgtgaatc aaaagcacta
     9241 atttctaagg gagttagtgc tttttagtta attatataaa attttagtaa aggagacatc
     9301 tatatggata ttcagttaaa tatattatta tttttccaaa atttaagaaa tccaattttg
     9361 aactttatat ttcttgtctt tacaataagc acagaagcac cgttattaat attaattaca
     9421 acaattatat actggtgtat aaataaaaaa tgtggacaga aaatactgtt tgctataatt
     9481 ggaaattttg ttgtaaattt aggcatcaaa gagtttgtaa aagctcccag accaatagga
     9541 ataaaaggtc ttgaatcatt gagagtttct actgctggtg gttattcttt tccaagtgct
     9601 catactcaaa ctgcaacaac attttgggtt agtattatga ctatatttaa aaagagatat
     9661 cttcatttaa tagctgcagt tatggtttta ggagtaggat tgtctaggct gtatttagct
     9721 gttcattggc caatagatgt gatagcgggt tggatattag gaatattttt tacagttgta
     9781 tttgtaaaaa tatttgacta tattgatgat aataaaaatt atattttact tgtagtttta
     9841 cttataccat ttataatagt ggctatattt ctaaatagcc ctgaatattt tgaaaaattt
     9901 ggtataatag taggatttgt atttggatat atggttgagg atagatttgt taaatttaat
     9961 acagataata ataacaaaaa aataaatttt agtaataaaa ataaggggag taaaaatata
    10021 attttttcaa gaatatgtag gtttttggtt gggatagtaa caataggaat gttatatatt
    10081 ggcattaagt tgtttatttc aatgttaata gtcactttaa atataagtga ctctactatg
    10141 agtataattt ttatgaattt tattaagaat acagtagttg ttttttatgg aatagcagga
    10201 gctccagcat tatttaaact tttaaaatta aattgatttt aaggtataga gtcaatagtt
    10261 taaattaaaa aaattaaggg tagaaaagag tgattatttg aagaagatag taataatagg
    10321 tggtggacca gcagggatga tagccgcatc aactgcatgt gagaaaggct atgatgtaac
    10381 attaattgag aaaaatcata aattaggaaa aaaacttgca ataacaggaa aaggtagatg
    10441 taatattact aacgcttgtg aaatagagga attaatagaa aatgtaccta caaatggaaa
    10501 atttctttat agtgcttttt atacttttac aaatgatgat gtaataagta tgtttaataa
    10561 tcttggagta aagactaaaa cagaaagagg aaaaagggtt tttccagaga gtgataaagc
    10621 atttgatatt gtaaatgctc ttgaaagaca acttaaaagt aagaaagtaa atatattatt
    10681 aaattcgaaa gtagaaaaaa taatatctaa aaataataaa attgagaaag taattttaaa
    10741 cgataaaaaa gaaattaagt gtgattcagt tgtagtagca actggtggat taagttatcc
    10801 acttactggt tctactggtg atggatataa atttgcaatt tcacaggggc acacaattat
    10861 agatacaaaa ccatctttaa ttggtataga agtacaagaa agttttacaa aagatttaga
    10921 aaaattatca ttgagaaatg ttgaaataag ggtgtttaat agcaaacaaa agaaagttta
    10981 tagtgatttt ggagaacttg aatttactag atttggttta gatggaccta taatcaagtc
    11041 tgcaagttgt agaatgaaag atacaaggaa agaaaattac actatattat tagatttaaa
    11101 acctgcatta gatgaggaaa aactggataa aagagttcaa aaagattttc agaagtatac
    11161 aaataaaaaa tttgaaaaag cattagatga tttacttcca aaaaaactaa tacctataat
    11221 aataaactta agtgaaatta atccaaatac ggttgttcac caaatttcta gagagcagag
    11281 aaaaaactta gtccatttat taaaaaattt aaagtttaca gtaaagagat acagacctat
    11341 tgaagaagct ataataactt ctggtggtgt aaaagtaaac gaaataaatt caagtacaat
    11401 ggaatcaaaa ttagtagaag gtttattttt tgctggagaa gtaatagata tagatgcata
    11461 tacaggtgga ttcaatttgc aaatagcttt ttctactgga tatttggcag gttttaattg
    11521 ctaaaaatta cctgaattaa aaatgtttaa aatcacataa tattatcagc aacacaaaat
    11581 aaattaaaca gaaggaaggt aatcaacatg gcaagtaaca ataacaacaa cagaacagta
    11641 gtaccaggag caaaagaggc tttaaaccaa atgaaattag aaatagctaa tgaacttggt
    11701 atgagtaatt atcaacaagt tgataaagga aaccttactg caagagaaaa tggttatgta
    11761 ggtggataca tgactaaaaa attagttgaa atggctgaac aacaaatggc tggaaaaagc
    11821 aacagatagt tataaataat tatttataac tattggctat tagtttagct agagctatct
    11881 caaatataga aagtaatttc taaattgaga tagctttttt ttattaaatt attaaataga
    11941 tatattttta tgtaataaat tttatgtatt tggataaaat aatacaaatg aatatgttac
    12001 ataaggagtg atgtaaaatg agtagtgtaa attttgagga tttaaaaaat aaatttatta
    12061 atagtgactt agatgaaaaa ataagaatat atacaacaac agaaggttta tcagtagaac
    12121 aatttaaaga gctactaaaa tattatccaa tacaacattt atctaaacta gaaaaagcac
    12181 ttggatagca gtatttaatc caaaattaaa aaggcaattt atttaatatt aaaaatattt
    12241 tttattaaat aaattgcctt tttataatag gtttaaatta ttatgctttt gatatataat
    12301 tgtagattct ctcatttcca agttcaatag acccagtatt aataagagta acgattcctt
    12361 ctatatctct agcagttaag tatttatatg gaattaataa attataacca gtattactta
    12421 gtaagttttt taattgggtt atttgagaga tattgaaaca ttttgcagtt ttagtagatt
    12481 tttttcttaa gttagataaa ttttcatttt gaatatttat taaagtttct atatagtttc
    12541 tataagatat cttaaagttt gtctcattga ctattttttc attaagtata ctactgataa
    12601 aatcttgaga caatatatta tctgcaaatt tatctgctgt taattttcca gatgttatgc
    12661 ctttttgata ttttctaaga atttttttag tatagcagta tattttattt ctcgtttcta
    12721 aatcgagttg ttctatttgc acaaaaccac ttccttctaa ttataaaaat atttattaaa
    12781 aatctatact taactaataa agcttcaata acttatttac aataaatact aaatcataaa
    12841 atatttgtta ttttttatta ttaccaagta taaaaaatat tataattgta aaacttacaa
    12901 atatatgtaa aatatttagg agtgatgaaa atgttaaatg ggataataaa gcttttttat
    12961 tctgaaattg taaaaacaaa gattaataac ttagattcaa gtggatattc tttaagagat
    13021 gaatgtaaag aaatcagaaa tataactcta aagatagata gtgtattttt taagctttta
    13081 aagttagctt ttggttcaat attgcttatg gtagctttta atttaaacat ggttttaggt
    13141 ataggagtgt ttttagttgg tgtagtttat atactatata aaagaaatat ggaagaacaa
    13201 gtaaaagagc atataaataa tgtgaaaaat aatatcgaca tctctaaaat aacttttatg
    13261 gatgaaaaag ggagaacagg tctaaatgca ttaattacat tacttcttat aggattattg
    13321 acaggattta actggatatt agttgctagt tttgtcgttg tttttgtttt tactataaag
    13381 aatgtatgtt aaaatactaa taaatagttt aatatatagg gggagaaatt gagtatgact
    13441 aatggcagtt ataaaatgaa gaatttagtg gaaatatccg ctatggtgac tgaatctaca
    13501 gattttttta atataaaaga tgacataata gaaaaaatgt tagaagttgt tcaccctaca
    13561 aaggcatgtg tgaatctatt ttataaaaat gattctaaat atgcctactt agtatgttcg
    13621 caaaccttag aatatgtacc tcaaattttt ccaataaata gtcttaaagg tgcaaaaatt
    13681 gattttgaca catatccaga gtatatacat gaggctgtaa atgaaaaaaa aataatatat
    13741 gtggaaaatg tatttgaaga ttctagagca gaaggtgaac gagatttagc aaaagctgaa
    13801 ggttatattg ggagaatagt ttttcctttt ataataaata acgtagttgt tggatttatg
    13861 acttgttttt taaaagagga tgattatata acagaacaag atatagattt tatatcatct
    13921 gttgcatcac tcttaagttt atcaatagaa ataactaata aaaataataa tgtacaaatt
    13981 ttaattgata aactaagagg ctcaataagt gccataaatg aagctactaa aaaactatac
    14041 cttaataaga gtattgatgg atttttggaa aatttaagta aacaagcgtg taatattact
    14101 aatagtaaag aagctttaat aattataaat agtcatcata ataaggatgc tatagttagt
    14161 tgttataatg ttgagcaaaa aaagaaaaca aatttatatc ctatgattga tatgttttta
    14221 aagaaagagt cattgggggg gtatttaaat aatttaaaac catgctcaaa aaagggaata
    14281 aatttggaaa gttatatata ttacaaactt caggataaaa atgagactat aggatgtata
    14341 gtttgtgcaa atagcaaaaa ctatactagt gatgatttaa atattcttag tatattgtcc
    14401 aaacaagttt ctgttggtat gcaattatat gaacataatg aaaaggaagt aaaacacaaa
    14461 gttcttgaaa acgagttgaa catattaaat aaacaacaac agcttattat ggataaaggt
    14521 aaaatggatt gtaatgatga gaaagaactt tatttttacc ataaaccagc aagggtagta
    14581 ggtggagatt tttattatgc tacaaaagtg gatgatgaac atatagttta tattgttgct
    14641 gatgtaatgg gacatggaat ggtatcaaat tatgttgttg caatgataaa aggtgctttt
    14701 aaagtattat gcaatcaata caatacacca agagaaataa tgacaaattt aaataggatg
    14761 ttatatgatg aatttgacaa gatgggagta tttacaactt gtttgatagg tattatagat
    14821 actaaagaaa atatgattac tgtgtctaat gcaggtcact atagtcctgt agttgtaaag
    14881 aaagatggca caatagaaaa taatttaaat tgtaaaaagg gcatacctat tggaataatg
    14941 gaagatgcta cttatgaaaa taatactctt tcaatggaag attatgcaat ggtatgtatg
    15001 tacactgatg gaattttaga gataaaaaat tcatcaaaag aagagtatgg tataaacaga
    15061 ttagaaaact ttctaaaaga aaattttaga ttaaatcaac agttaatagt agaaaatcta
    15121 aaattggatt taaagaactt ctcatcaaaa gataattatg atgatgatat tttaatagtt
    15181 atgttaaagg ataggtagat tgattatgga ttcaaacgat aaaaaaggac ttaaaagtcc
    15241 agagattata ataataaatg gaagtccaag aattaataaa aattgcagtt ttatagcaaa
    15301 tgaagtaaaa gctatgctag aagagtgtgg attaagttgt aaaatattta atatctacaa
    15361 tatggatatt gaatattgca cagcatgtgg attttgtgaa aaaacagggt attgcaagtt
    15421 taatgatgat atgaagccat tatataaaat gtttgatgat tcaaaaggaa ctatagtaat
    15481 aagtcctgta cattttgatt caatatcagc taaattaaag actgttgttg atagaactca
    15541 agctatatat gcaagtaaat atgtattaaa taaaccttca attgatagaa gtaagaaacg
    15601 gataggaatg tatattgcag tgggagggag taaatcatat gattcacagt ttaaaggtgg
    15661 acagattgtt atggattttt tctttaagag tataaatact aaacttttac acaatatata
    15721 tttaaacaat acagatgatg tatcttatat agataatcaa gaatttaaag atataatata
    15781 taaaaattta aagatatata ttgattcaat ataatttgat tttgtaggta atattatgta
    15841 taattgtatt gcaataattt aaataattaa aaggagggaa tttcaatgaa attaccaata
    15901 gcattatcta ataaacatgt tcatttgagt caagctgata tagacgtatt atttggagca
    15961 ggtcatgagt taactaaatt taaaccatta tctcaaccag ggcaatatgc ctgtgaagaa
    16021 aaagtggatt tagtaggacc aaaaggaact ttaaaaggag ttagagtact aggaccagct
    16081 agagctcata ctcaagttga aatatcttta gcagatggtt tcccattagg agtaaaagca
    16141 ccaataaaag aatctggtga tatagctgga actccaggtg ttaaattagt aggacctgct
    16201 ggagaagttg aaatgaaaga aggagttata gttgcttcta gacatataca tatgagcaat
    16261 gaagatgctg ctaaatttgg tgtaactgat aagcaaatag taaaagttaa aacatctgga
    16321 ccaagagcat tagtatttga aaatgtatta gtaagagcta gcgacagctt taatctagaa
    16381 atgcatgttg atatggaaga gggaaatgca gcaggcgtta aaaatggaga tttagtagaa
    16441 ttaatagttg attaatatta taaatagact ttatgctagt agatatttta tttgctagca
    16501 tatttttaaa tgtaataaat ttctatagga taaatttaat cgattagatt aatttataaa
    16561 ataaaggggt attataaaaa atgtaataaa aacttacaaa aatatgatgt aatatggtaa
    16621 aattatatat ataaaaattt acatgtaata aggataagca ttttactttt tatactaata
    16681 tgaacaaata gataaaaaag tttgaaaaat ctaacttaat ttattatata ttgtatacaa
    16741 aattatgaaa aaaacttaac atatttaatt ttaaaaaaaa tctacttaaa tatgtaatta
    16801 atttacaatt ttcaaaggaa ttttatctaa tctgtagtat tatattagaa gatagagtat
    16861 ttgcgcgact atatgtgtgt ttatagtttt gttgtgtaaa ttatatgtaa atataaaaaa
    16921 atagacttgt tataaacaag tacaattgta gctatcaagg aggatacata ttatggctaa
    16981 gtttatgaaa acacttgatg gaaatacagc tgcagctcat gttgcctatg cgtttacaga
    17041 tgtagcagct atatatccaa tcacaccatc ttcaactatg gctgaagtag ttgatgagtg
    17101 ggcatcacaa ggaagaaaaa atatatttgg acaaacagtt aatgttgttg aaatgcagtc
    17161 agaagcaggt gcatcaggaa cattccacgg ttctttacaa ggaggagctt taacttctac
    17221 ttttacagca tctcaaggtt tattattaat gatacctaac atgtataaag ttgcaggaga
    17281 gttattacca ggagtattcc atgtaagtgc tcgtgcttta gcatctcaag cgttatcaat
    17341 atttggggat caccaagacg ttatggctgc tagacaaact ggatgtgtat tattagcttc
    17401 tggttcagtt caagaagtag ctgatatagc acctgttgca catttagctg caatagaagg
    17461 tagattacca tttatacatt tctttgatgg attcagaact tcacatgaaa tccaaaaagt
    17521 tgaattacta gaaaatgaag attatgcaag tttattaaac tttgaagcag ttcaagcatt
    17581 tagagataat gctttatctc caaatcatcc agttgctcgt ggtactgctc aaaacccaga
    17641 tatatatttc caaactagag aagcttctaa taaatactat caaaatatag taggtatagt
    17701 tgaaaaatac atggaaaaaa tgagtaattt aacaggtaga aaacatagtt tatttgatta
    17761 ctatggagca gaagatgcta aatatgtatt aatagctatg ggttcagtaa cagaaacaat
    17821 agaagaaact atagattact taaatgctaa gggagaaaaa tatggtttag ttaaagttca
    17881 tttatataga ccattctcaa tgaaacattt cttagatgct atgccatcta ctgttgaaag
    17941 aatatgtgta cttgatagaa ctaaagagcc aggttcaact ggtgaaccat tatacttaga
    18001 tgtacgtgat gtattctatg gaaaagaaaa tgctcctatg ataataggtg gaagatacgg
    18061 attaggttca aaagatacta ctccttcaga tataaaaact gtttttgata acttagtttc
    18121 agaacaacct aaaaatggat ttacagtagg tatagttgat gatgtaacta atacttcttt
    18181 aactccatct gagccaataa aaatagcttc taaaggaact ataagatgta agttctgggg
    18241 attaggttct gacggtactg ttggagctaa taaacaagct atcaaaataa tcggtgacca
    18301 tactgaaaaa tatgctcaag cttactttga ttatgactct aaaaaatctg gtggtataac
    18361 tatgtctcac ttaagatttg gtgatactcc aataagagct acttatttaa tagatgaagc
    18421 tgattatatt gcctgtcata aacaatcata tgtttatcaa tatgatttat taaaaggtct
    18481 taaaaaaggt ggtacatttg tacttaacac tatatgggac caagcaggac ttgaagaaca
    18541 tttaccagct catatgaaac aatatatagc taaaaatgat ataaaattct atacagttaa
    18601 cgctgttaaa ctaggacaag aaataggtct tggaaacaga ataaacatga taatgcaatc
    18661 tgcattcttt aaattagctg aaataatacc agaagaagat gctgttaaat acttaaaaga
    18721 ttctatagtt aaagcttatg gtaaaaaagg tgaaaaaata gttaatatga actatgctgc
    18781 tgttgatgca ggaataaatg ctttagttaa agttgaagtt ccagcttctt gggaaaatgc
    18841 tgttgatgca gataaaggag aagttaaaga accagaattt ataaaaaata tactaagacc
    18901 aatgactgca caagaaggaa acaacttacc agtaagtaca ttcaatggta tagaagatgg
    18961 aacattccct tgtggtactg cagcttatga aaaacgtggt atagctgttg atgttcctga
    19021 atggataata gataactgta ttcaatgtaa ccaatgttct tttatatgtc ctcattcatg
    19081 tataagacca gtattagtta ctgaagaaga attagctaat gctccagaag gatttgaagc
    19141 taaaaaagca ttaggtaaag gattagaagg attaaaatat agaatgcaac ttagtccact
    19201 tgactgtaca ggatgtggaa actgtgctga catatgtcca gctaaagaaa aagctttagt
    19261 tatgaagcca atagatactc aacttgatac agagttagat aattgggcat ttgcagtaaa
    19321 tcctgatgag gtagctccaa aaggtgatgt tatgcctgca aacactgtta aaggaagcca
    19381 atttagacaa ccattaatgg agttttcagg agcatgtgct ggatgtggag aaactgcgta
    19441 cattaaagta gttacacaat tatatggaga tagaatgatg atagctaatg ctactggatg
    19501 ttcttctata tggggagctt ctgcaccatc aattccttat acttgtaacc atgaaggtaa
    19561 aggtccatct tgggcaaact ctttattcga ggataatgct gaatatggat ttggtatgta
    19621 cacagctgtt aagcaaataa gaaataaaat agtagatgct atgatagagt tagtttctat
    19681 ggatatctgt gaagatgcta aagcagtatt tacagagtgg ttagattcta gaaatgatgg
    19741 agaagcttct aaagtagcaa gtgctaaggt tgttgaatta ttagaaaaac cagcttgtga
    19801 ttgtacagat gaaaaagcta aagaattagt aaaagctata aaagatagaa aagattatct
    19861 agttaagaga tctcaatgga tactaggtgg agacggttgg gcatatgata tcggttacgg
    19921 tggattagac catgttcttg catctggtga agatgtaaat gtacttgtat ttgatacaga
    19981 agtatattca aatacaggag gtcaagcttc taaagctact ccagctgctg ctatggctaa
    20041 gtttgctgct tcaggtaaaa aatctagaaa gaaagattta ggaatgatgg ctatgacata
    20101 tggaaacgta tatgtagctc aagttgctat gggtgctgat aaaaaccaat ttatcaaagc
    20161 cgttatagaa gctgaaaaac atgatgggcc atctttaata atagcttatg ctccatgtat
    20221 aaaccatgga ttaaaagaag gtatgggaag aactgtagct aacgaagcac aagctgttgc
    20281 ttgcggatac tggcatttat acagattcaa tccagaagta aaagctgaag gtaaaaaccc
    20341 attcacttta gattcaaaag aaccaactgc aagcttcaaa gatttcatac ttgcacaagt
    20401 aagatattct gctatagcta aacaattccc agaggaagct gatggattat ttgctaaagc
    20461 tgaagctgat gctaaagaaa gatatgaagg atacaaaaaa ttagctgaat aatattaaag
    20521 tattataatg cttatataga attgataaaa gagagtgtct caaagtgagc tttttagttc
    20581 atgaggcact ctttttatat gaaataacat atgcctatca tttcaacaat gaaaaaggcc
    20641 ttatctctat tttgagacag ccttttttta tgaagatatt aagattttgt ttttacctat
    20701 taaatatctt ttttaagttt tccattttca tcttgccaat actttttata tattgtttta
    20761 cacactaaaa ttaagagaac aaataatatt tatagtatgt atatttggat ttgataattt
    20821 taaaatagac acaaaagagt atctcatttg tgttttttat cacttagaga tactctcttg
    20881 atatgtatgg aaaaagagta ttttatccta caaagatttg tgtccaataa attgaaccac
    20941 cacttttttg tgctactcca acacctattt tactgaaatt tggattcatt atattttttc
    21001 tgtgaccttc agaattcatc catgcgttta caacttcttt aggagttttt tgacccatag
    21061 ctatattttc acctgctgtc ttatagctta ttccaaattt tttcaacatg tcaaatggag
    21121 aaccataagt tggagaattg tgtgaaaaat agttgttatc aatcatatct tgagattttt
    21181 ttgtagcaac atttgatata gaagaatcaa gagtaagagg atttaatcca gctttagctc
    21241 tttctatatt tactaagtca acaacttctt tttggtaagc tgaaaaactt tcacttgtag
    21301 agcctgagtt gttattatca tcaggtttgt tagtagagtc tgaattattg ttgtcttcag
    21361 gtttattaga ctcaggttta ttgttatcag gtttatcagt agagcctgaa ttattgttgt
    21421 cttcaggttt attagactca ggtttattat tattaggttt attagtagag cctgaattat
    21481 tgttgtcttc aggtttatta gactcaggtt tattgttatc aggcttatta gtagagtctg
    21541 aattattgtt gtcctcaggt ttattagtgt tgttgcaatt cttgtcatta tgattcttat
    21601 ccttacaaga gttatcttta tcaggcttaa gttctggttt tacagaacaa tttggttttg
    21661 cagaaaactt gtatttagta ttactatata ctaaactttt gttacttata tttacattat
    21721 tttcaagtga tgaagcactt gcagtaacag cacttgaagc tgttgctaaa gttaacactc
    21781 ctaaagctaa tatagttttt aattttgttg gtatatttct tctcatcatt aaacacctct
    21841 taatctaaaa attctaaaaa tgttactgat ttgtaacctt tagtgtaggg ggttacccgt
    21901 gaatctatac taacataaga ttaagacttt ttttactgta aagatatgta aaaaagatat
    21961 atatggaata aataggtata tttcagtgtg tttgacaatt tgtattaaaa gcctgtatag
    22021 tatggaatta cttagttaga gaaaataata tttttataat aattccataa cgtaaattta
    22081 tagttatgat aaattttttt ttatttggtt aaatttattc agtagatgct ttcgtattag
    22141 caacaaatta taattattta aatctttaag aaataaaaag ggtctgtctc aaaatagaga
    22201 taaggccttt tttattgttt aaatgatagg catatgttat ttcatataaa aagagtgtct
    22261 cattaagtaa aaagttcact ttgagacacc acctttcata ttatgaattt taacttgttt
    22321 tatattaata cattagtaat cctaatgtaa ttacaataat ttctgctatt agtgaaccaa
    22381 ctgcaactac aatgaaagtt tctttaaatc cagttttatg tgttaactta gataagctta
    22441 agaatgtaag aaaaacacca ctttgtggaa ctatagttag tatatttgaa gctattgtag
    22501 caacacggtg aattaattct ggatttagac cagtacttaa ataataatct gcaaagtttg
    22561 gcattactat tcctaatgca ccagaagagg accctgttat tgctgacatt gttgaagtca
    22621 aaacagtaag acttataagt ggactacctg gtattgacat tataagtttg ctaaatacat
    22681 caaaaccagg tgcagccatt attactgctc caaatgcaac tgcagaagat gtagcaaata
    22741 taggacctat agaaccacta gcacctatgc tcaatgtctg tatcttagat gatagaaatt
    22801 tatggaataa aaaagcagat aaaagaattg caactattaa agctatgtaa attacatttt
    22861 ttttcataaa ttctgaacca aaagtacttc cagttatagc tataattacg agtgctaata
    22921 gaggaaaaat acttgcaaaa aatcctggta attctctatc taaagattct tcttctaatt
    22981 ctgaagtgta agttgcataa gtttcacctt ttctaatact tttgtttaga gcatatttca
    23041 tatagacaag tccaaatgta gcacaaccta tactacctac aatacttggt atagtagctg
    23101 cagtaagaga cgtatttaga tattgaatag gtataacatt ttgaatggct ggtgttccag
    23161 gaattatagt catagtaatt gttgcaatac caagccaaag tggtatctga ataaggttcc
    23221 aagaaatatc aagtttttta aatagagttc ttgcaagtgg aatgaccgca aacataacta
    23281 caaataagct tataccacca tacgttaata taaaacttac tataaatata gcaactaaaa
    23341 ctctataagg atgattagag ccaaatttat ttaaaataaa atcagctatt gatacagtag
    23401 ctccactttc ttccataaat ttagcaagta ttgagcctaa taagaatatt gcaaaataac
    23461 tcattatata gtttccaagt gcacccatat aattgttttt gtcagcacct agcattgacg
    23521 ttacaacatc cattttattt aaaataacaa ctattaaagt tgctattgga gcagctatag
    23581 ttatatgaat ttctttaact gaaaaatata taatagctat gataccaata attataccaa
    23641 ttggcgcgat aatactcata aatatccctc cttagtagaa ggacctgaag aatactttct
    23701 tcaagcccta aatataataa ctattgtgca gtatatcctc catctagtaa gcaagcttgt
    23761 cctgtaatac ccttagcatt atcacttgct aagaacatag catagtcggc aatttcttga
    23821 acatctaata ggcgtttttg tggtacaagt gggtataaaa cttcctctaa gacattttcc
    23881 aatggtatat tacgagtttt tgaaaggtca ttgaactgac ctctgacaag tggagtatct
    23941 acatatccag ggcataaagc attaactgtt ataccagaat cggcagcttc aagagcagca
    24001 acttttgtta gtccaataag tccatgtttt gctgagttat aagcagcctt tccagcaaat
    24061 cctattacac cattgattga ggccatattt attatacgac caaagccttg ttttttcatt
    24121 ataggaaatg cttttttagt agctataaaa ggtgctgtca gcattatttt tatcataaat
    24181 tcaaatttat cagttgggaa atcttctatc atagaaacat gttgaagtcc agcattgttt
    24241 attaatatat ctaatctgcc atacttttca acagttttgt ctatagcgtg gttaatttct
    24301 tcttccttag ttacatcaca ctttacactc atgcaatcat aacctttttt ttgtaacttt
    24361 gttatggtat tatttaaagc ttcttgattt atatcagaga acattacttt agcaccattt
    24421 tttaagaacg attcagctat ttgtttacct attccacttg cagctcctgt tacgaataca
    24481 actttatctt taaccatttt catttcctcc aattttattt tatttttata ttaatatttt
    24541 aagcaataaa atctttctaa aaagtccgat tatcccctaa aacactgtat ttatcgtatt
    24601 ttttgaggac ttcaaacttt gaatttacca cgaatttact acaaacgagc aagccttgaa
    24661 ctcgatacga agtcccagct ctgatagata tggtacagca catcagtatt gataaactaa
    24721 aaattgaata ttgtaagtag attatggaac gccgatattg acgttccttt tctattttca
    24781 gccgttcaga aatggacggc tttttctata tccaaacgaa aggagaattt taaaagctat
    24841 gaaaaagata ttgaagcgat tagccacagg cttccttgcc tttgcgacta tcgttaccgc
    24901 tttgccgaca acggcagtcc acgcttccga gaagcaatac tggacagaaa gtgccgagcg
    24961 tgtcggtatt gttgaaaaag taatgaatga cggctctatc ggttcgacat tcaatgaggg
    25021 acacatgacc gttgagggcg aggacgcttt ctgcgtagat attaacacca acttcaagaa
    25081 cggctataag accagagctg acgcaagcac acgcatgagc tacgaccaga tttccgacgt
    25141 tgccctctca atcgagtatg tcaatcagta tgtgcagagc cacagcggat tgagcagtca
    25201 gcatatctac cttttgaaac agtgcgtcgt atggcagaga ttgagcgttc atctgggctg
    25261 gcaatgcgat aacgtcagag cttcctatga tgaaatccca aaagcgatac aggacgaggt
    25321 gtacgctggg gcgaaagcct ttgccagtga gaacaaggga cgctatgaat gtggcggtta
    25381 tatctactct ggcgagggac aggacattgg acagttctgg gcgaaacttg ccgtaggaaa
    25441 tgccaccctt aaaaagactt ccagtaatgc cagcattacc gacgggaacg ggctttactc
    25501 tatcgctggt gcgacttatg gtatctattc tgataaggac tgcacgaaac agcttgccac
    25561 ccttacgact gataacagcg gaaatactga taccgtggaa gtaaaggctg gtacagtcta
    25621 catcaaagag ctttccgctc ctgctggcta taaggtagac agcactgtat attccttaaa
    25681 tgtggaagcg ggcaagacag cgaccttgaa cgtatccgat acgccaaagg ttacagatac
    25741 ccttatcgag cttttcaaga ttgacatgga aacacagaaa gacgctccac agggcgacgc
    25801 ttccctagag ggtgcggagt tcacatggaa attctatgcg ggacactata ccgctgacaa
    25861 tctccctagc gagcctacca aaacatgggt gacaaagaca atcgctgaaa aggacagcga
    25921 cggcactatc cattacgttt cccgcctttc tgatgaatac aaagtatctg gggacagctt
    25981 ctatacacag gacgataaga acgtgcttcc tttagggacg ctgaccgttg aggaaacgaa
    26041 agcacctaac ggctatcttc ttgacggtgc atatatgcag gcaaacggta gcgaggaaca
    26101 gattaaggga atgtacctta cacagattac cgaggacggc gatattgccg tactgtctgg
    26161 aagcaatcag taccatgtat cagacaaggt tatccgtggc ggtgtgaaaa tccagaaaag
    26221 agatttggaa accagcgata ccaaaggtca aggaagtgcg accttgaaag acgctgaatt
    26281 tgaaatcatc tccttaaatg acaatgccgt acttgtcgag ggcaagctct acaataaagg
    26341 cgaagtggta aagacaatcc ttaccgacat tgagggcgtg gcttctactt ccgctgacct
    26401 cttaccttat ggaaaatacc gtatcgagga aagcaaagca ccagagggct atttgacgga
    26461 cggtgcagaa ccgattgaat ttgaaatcac agaggacgga aaaatcgttg accttacagg
    26521 gacagacaca tcaatctaca atcaagtgaa gcgtggcgac ctggagggtg tcaagattgg
    26581 tgctggcaca caccagcgtc ttgcgggagt tccgtttagg atcacaagca agaccacagg
    26641 tgagagccac attatcgtga cagatgataa cgggcagttc tccacttctt ctgactgggc
    26701 ttcccacaag cacaacacca atgcaggaaa gaccagcgag gacggtatct ggtttggaac
    26761 aagcgagcca gacgacagca agggtgcttt gatttacgat acctatatca ttgaggaatt
    26821 acgctgtgag ggcaacaaag gctttgagct tatcccaccg tttgaaatcg tggtgtccag
    26881 aaacaacgtg accgttgact tagggacact cactgatgaa tacgagaaag aaatcactat
    26941 ccataccaca gccacaggca aggacggcga gaagtctatc gtggctggca aagaggtaac
    27001 aatcattgat acggttacgc ttgacggact ggaaaaaggc acaaagtatc agttgaaagg
    27061 ctggcagatg attaaggacg aaaacgccga gcttcttatc gacggacagc gtgtagaaaa
    27121 tgattacaca ttcacagccg acagcgaaga aatgaagatt gaaatggaat atacgttcaa
    27181 cgcttcttct ctgggcggtc agaaccttgt aacctttgag gaactttacg acctttccaa
    27241 tgaggacgag cctgtaaagg tggcagaaca caaggacatt gacgacgagg gacagacggt
    27301 gcttatcaca gagcgtatca tctctatcca taccacagcg accagcgagg acggaaagaa
    27361 agagattgaa gcaggaaaag acgtgacaat cattgatacg gttacgcttg acggattgga
    27421 aatcggcaca aagtatcagc ttgtaggctg gcagatgatt aaggacgaaa acgccgagct
    27481 tatcatcaat ggtgaacgtg tcgagaatga ctataccttt actgccgaca gtgaaagcat
    27541 ggaagtccag attgccttta cattcgacgc ttccgagctg ggcgggaaag agcttgtgac
    27601 ctttgaggaa ttatacgatt tgagcaatcc agacgaaccg acaaaggtta cagagcataa
    27661 ggacattgag gacgacgggc agacggtgac aatcacagaa gtaccagaaa cgccagaaga
    27721 accaacagag ccagaacagc cgaccacacc agatacaccg agcaagacaa cggacgctcc
    27781 aaagacaggc gacaacacaa acattgcctt attcttaggg cttcttgttc tttctggtgc
    27841 aggcgtggca ggaacatact tcttcaagcg tagacgctct taatcgggcg gtctgcttat
    27901 gatgatgaag aaatcccgtt ccccgccgta tgttctgatg taacaggaaa tgaaaattta
    27961 aactgtttct tttctgttaa tctgcttgcg gattgacgga aaagaacagt ccactagggg
    28021 cgtggggagt gtagctcccc acatatcaat cacagaaaga aatgaggtag aaacacatga
    28081 aattaaaata tatcgtgcct gacatggcac agacttttgg aaatttggag tttgcaggag
    28141 aaaatgacgt ggagcaacag cgtgtcaatg gtcgctttgt tcccgtgacg agaagctata
    28201 acctgtattc cgacattcag agagccgacg acattatcgt ggtgcttccc gcaaaggctg
    28261 gtgaaaagcg tttcaagtat gagcagaaag tcaagctcgt caatcctaag attaccgccg
    28321 agggaaagaa cgtgcgaggt cgtggctaca ccaactatat tttaaacgct gacgatatgc
    28381 ttccagtcga ggaaagcaag taaagggggt atcagattat gagattagcg aatggaattg
    28441 tattagataa ggaaaagact ttcggtgttt tgaaattctc tgcccttaga catgaggtgc
    28501 gtgtagagaa tgaggacggg acgaccaccg aggaaatcaa gcgtagaacc tatgatttga
    28561 agtgcagtca gcaggaacgc acgatacagg tatctatccc agcggaaatc cctgtcaaag
    28621 actacccgta caatgccgag gtggagctta tcaatcctgt tgctgatacc gtggcaaacg
    28681 ccaactaccg aggggcagac gtggaatggt acatcaaggc agacgacatt gtgctgaaaa
    28741 ataaaggcgg tcagcccgca ggaaatccgc agaaccatgt tccgcaggga cagcagaaga
    28801 aataaaattg ctaactagat tttcattgta gctgttatat tgaattggta taatatgggt
    28861 atgaagtaag cgatagaaaa ggattttgtg caataataac agatgttaat ctgcgttgct
    28921 tgtggcaacg gctgttttga tatttaatag ttgtatcaaa acaaaggagg cataggttat
    28981 gttaaacgaa aatattagaa cactacgaaa ggcaaaagga ctttcacaag aagaattggc
    29041 tattaagata aacgtagtaa gacaaacagt atctaaatgg gaaaaagggt tatccgttcc
    29101 cgactcaagt atgcttgttt cgttggcaga agaacttgat acgtctgtaa gtaccttgct
    29161 aggagaaacc gtacaagaag aatgtttgaa cgagggagac ttaaagagta tttctgaaaa
    29221 acttgaagtt atcaatctac agtttgctaa aaaaagcgaa aggaaaatta aaactattcg
    29281 ttactcactt attttagtgt gtgtatttat tgcagtagta tttattgctc tcgtaactat
    29341 gaatagtgaa tatttggctt gggattttaa taacccagaa ttagcgattg taggcactct
    29401 actacatggt ttcgagtttt tgtttgtgag attagcacct tttgttttta tcggttctgt
    29461 aatcggtatt gtactcacat atagaaaacg ataatttcat atccagtatt acaaaagcgg
    29521 ttagtctata cgattgaccg ctttttccat atccagaaag gggtgtttat gaacattttg
    29581 aaatacaagg gaaagcgtat cagagccagc gacaagaacc ttgtgtaccg cttctgtgca
    29641 ggtacgctcc tgctactgtt cgtggcggtt ctcctgctac tgaacatggg acagctcatg
    29701 cgtaccgatt gggaacattt cagcttacta gataatgggc tgacgctttc cacatacaac
    29761 ttcataacga ttttgatagc gactggtgtt tgtgcattgg tcgcttttct ttattaccgc
    29821 ttcttccatg acagctttaa aaaattactg caccgtcaaa agctggcacg catggtactg
    29881 gataacaagt ggtatgaagc ccagaccgta caggacagcg gctttttcac tgacctgcag
    29941 agcagatcaa gggaaaaaat cgtctggttt cctaaaatct attatcaaat ggacacaggc
    30001 ttgctccata tccgctgtga aatctctttg ggaaagtatc aagaccagct tttgcgactg
    30061 gaagataagc tggaaagcgg gctttactgt gagctgaccg acaaaacgct ccatgacggc
    30121 tatatcgaat acaccctgct ctatgacatg atagcgaacc gtatcacgat tgatgaggta
    30181 aaggctgaaa acgggggctt gcgtctgatg aagaacctta catgggaata tgacgcactc
    30241 cctcacgccc ttatctgtgg cgggactggt ggtggaaaga cctatttcct gctgacaatc
    30301 attgaagccc tcttgcagac caacgcccag ctttacatct tagaccctaa gaacgctgac
    30361 cttgcggact tgggtacggt catggataac gtgtaccaca ccaaagaaga tatgatagag
    30421 tgcgtcaatg cgttctatga gggcatggta cagcgaagcg aggaaatgaa gcaccaccca
    30481 gactataaga cgggtgagaa ctatgcctat ctgggtttac cgccctgctt ccttatcttt
    30541 gacgagtatg tggcgttctt ggaaatgctg gggacaaagg aaagcataag cctacttagc
    30601 cagctaaaga aaatcgtcat gcttggcaga caggcgggct atttcctcat tgtcgcctgc
    30661 cagcgtcccg acgcaaagta tttttcagac ggtatcagag agaacttcaa cttccgtgtg
    30721 ggcttggggc gtatcagcga acttggctac gatatgctct ttggaagcga cgtaaagaag
    30781 cagttcttcc agaagcgtat caaagggcgt ggctattgtg acgtgggtac gagcgtcata
    30841 tcagagtttt acactcccct tgtaccaaag ggacatgatt ttttacaggc tatcggctca
    30901 ctcgtcctca caaggcagga cgggacggcg acgtgcgaag cgaaaggcga cggaacggac
    30961 tagccttgct ggtgtggcgt cagccacgcc agcgaaagaa gcccctcggt atctaacaga
    31021 ggggcacaat tccgctggaa actacggtca aaaagtctgg aaatcccgct aggcataagg
    31081 gttttcgctc actcatggct gactgtgaca atcggcggaa aatatcacag atttctataa
    31141 atacacgatt gggggtatgc aggctgaatg aaagcacctt tataaccgcc ttgaaagaga
    31201 aacgcctatc ttacggcgta tcccagacaa ggcttgcaat catggctggt atcagccgtg
    31261 aacacttgaa ccgtatcgaa gcgggaaagg tcaagctcac ggacgatatg caggacaagc
    31321 tcatggaagc ggtcgagaaa ttcaatcccg acgctcccat gttcctgctg ttcgactatg
    31381 tgcgtatccg tttccccacg ctggatatac agcacgttat cagagatata ttgaagctca
    31441 atgttgacta tatgctccat gaggattacg gacactacaa atacacagag cattactatc
    31501 tgggtgatgt gttcgtctat acttcacggg acgaggaaaa aggcacgctt ctggagctga
    31561 aaggaaaagg ctgtcgccag tttgaaagct atctgctggc acaggggcgt agctggtatg
    31621 acttcctcat ggacgctctt gttgagggcg gtgtgatgaa acgtcttgac cttgcgatta
    31681 acgacagggc gggcatactg gatattccag atctgaccgc caaatgcaac cgtgaggaat
    31741 gtgtttccct gttccgttct ttcaagtcct atgcttcggg cgagctggtg aagcacaacg
    31801 agcaggacaa ggcgggcatg ggacacacgc tgtatatcgg ctctctgaaa tcggaagtct
    31861 acttctgctg ttatgagaag aactacgaac agtacgcaaa gctgggaata ccgattgagg
    31921 aagcacccat aaagaaccgc ttcgagatac gactgaaaga tgaaagagct tattatgccg
    31981 tccgtgaact gctgacctat tatgacgcag aacagacggc attttctatc atcaatcact
    32041 atatccgctt cgtggacaga gaaccagaga agcgaaagac agactggaag ctcaatgacc
    32101 gttgggcgtg gtttatcggg aaagaccgtc cgcctgtcaa gctgacgaca gacccagaac
    32161 cttacacgct ggaaaggacg ctgggctgga taagccgaca ggtcgcacct acgctgaaaa
    32221 tgctgaaaaa gatagacgct ggcaacagca caagctatct gaaagagatt gaggacaacg
    32281 caaagctgac ggaaaagcac ttgcagataa tccgccagca gacagcggac acagaggagc
    32341 ttatcacaga gtaaaggaga attgagatta tggcagaact tgtcaaggac ttggtactgg
    32401 tatcgctggg aatgggtatc ggtgttgtcc ttatgtgtat cgcacaggtc agcaaaatgg
    32461 ctgatgaaga aatggaagaa atcaaaaaag aaaggattga taaagaatga atttcggaca
    32521 gaactt
//
LOCUS       DAEPUT010000042        32486 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.043, whole genome shotgun sequence.
ACCESSION   DAEPUT010000042 DAEPUT010000000
VERSION     DAEPUT010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32486
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.043"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            514..1680
                     /locus_tag="KRL22_002136"
     CDS             514..1680
                     /locus_tag="KRL22_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HBH1272625.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYIAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMAKGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFESKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLVKCVAQEWYPIEY"
     gene            1702..3348
                     /locus_tag="KRL22_002137"
     CDS             1702..3348
                     /locus_tag="KRL22_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBH1272626.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMENESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            3445..4818
                     /locus_tag="KRL22_002138"
     CDS             3445..4818
                     /locus_tag="KRL22_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1272627.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNYIG
                     VISASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            5263..6216
                     /locus_tag="KRL22_002139"
     CDS             5263..6216
                     /locus_tag="KRL22_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBH1272628.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARVFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            6254..7216
                     /locus_tag="KRL22_002140"
     CDS             6254..7216
                     /locus_tag="KRL22_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HBH1272629.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            7241..8227
                     /locus_tag="KRL22_002141"
     CDS             7241..8227
                     /locus_tag="KRL22_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBH1272630.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDEDVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            8240..9286
                     /locus_tag="KRL22_002142"
     CDS             8240..9286
                     /locus_tag="KRL22_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBH1272631.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTGKETIVSTNTSKSSE
                     KKELKIENENSRMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            9453..11183
                     /gene="lpdA"
                     /locus_tag="KRL22_002143"
     CDS             9453..11183
                     /gene="lpdA"
                     /locus_tag="KRL22_002143"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH1272632.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEFKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            11600..14548
                     /locus_tag="KRL22_002144"
     CDS             11600..14548
                     /locus_tag="KRL22_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1272633.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            14526..14990
                     /locus_tag="KRL22_002145"
     CDS             14526..14990
                     /locus_tag="KRL22_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1272634.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEMDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVNLSEESVSDLLNSKLKN"
     gene            15103..15405
                     /locus_tag="KRL22_002146"
     CDS             15103..15405
                     /locus_tag="KRL22_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1272635.1"
                     /translation="MGVTNVAKKILVACGTRVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            15467..16831
                     /locus_tag="KRL22_002147"
     CDS             15467..16831
                     /locus_tag="KRL22_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH1272636.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPVASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADILQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVIFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            16866..17339
                     /locus_tag="KRL22_002148"
     CDS             16866..17339
                     /locus_tag="KRL22_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272637.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINNGNLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            17511..18161
                     /locus_tag="KRL22_002149"
     CDS             17511..18161
                     /locus_tag="KRL22_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH1272638.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECSSTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            18335..19267
                     /locus_tag="KRL22_002150"
     CDS             18335..19267
                     /locus_tag="KRL22_002150"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH1272639.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKYNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFDNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            19541..20254
                     /gene="ispD"
                     /locus_tag="KRL22_002151"
     CDS             19541..20254
                     /gene="ispD"
                     /locus_tag="KRL22_002151"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBH1272640.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            20251..20736
                     /locus_tag="KRL22_002152"
     CDS             20251..20736
                     /locus_tag="KRL22_002152"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBH1272641.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    20831..21039
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            21103..22818
                     /locus_tag="KRL22_002153"
     CDS             21103..22818
                     /locus_tag="KRL22_002153"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH1272642.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLVSQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            22940..24385
                     /locus_tag="KRL22_002154"
     CDS             22940..24385
                     /locus_tag="KRL22_002154"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH1272643.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            24825..26306
                     /locus_tag="KRL22_002155"
     CDS             24825..26306
                     /locus_tag="KRL22_002155"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBH1272644.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            26527..26682
                     /locus_tag="KRL22_002156"
     CDS             26527..26682
                     /locus_tag="KRL22_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272645.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            26827..28224
                     /locus_tag="KRL22_002157"
     CDS             26827..28224
                     /locus_tag="KRL22_002157"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBH1272646.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEYKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKIFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            28209..28622
                     /locus_tag="KRL22_002158"
     CDS             28209..28622
                     /locus_tag="KRL22_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBH1272647.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            28728..29486
                     /locus_tag="KRL22_002159"
     CDS             28728..29486
                     /locus_tag="KRL22_002159"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBH1272648.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLKEVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            29499..30236
                     /gene="rlmB"
                     /locus_tag="KRL22_002160"
     CDS             29499..30236
                     /gene="rlmB"
                     /locus_tag="KRL22_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBH1272649.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            30239..30766
                     /locus_tag="KRL22_002161"
     CDS             30239..30766
                     /locus_tag="KRL22_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBH1272650.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            30831..31478
                     /gene="sigH"
                     /locus_tag="KRL22_002162"
     CDS             30831..31478
                     /gene="sigH"
                     /locus_tag="KRL22_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HBH1272651.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            31552..>32486
                     /gene="tuf"
                     /locus_tag="KRL22_002163"
     CDS             31552..>32486
                     /gene="tuf"
                     /locus_tag="KRL22_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH1272652.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSALMALEDPKSEWGDKIVELFEQIDEYIPAPERDTDKPFLMPVE
                     DVFSITGRGTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRKLLDQAQAGD
                     NIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEV"
BASE COUNT        13230 a         3435 c         6198 g         9623 t
ORIGIN      
        1 tttaacctta taccatctaa ccaatttttt ctactttcgt aactttcaca cttaggttta
       61 tttcatcctt atgttttagt ttggttagct ttaggggttt ccagcaattc aagtagtgtt
      121 ggataggttc tatcctatct ctacatatat gtttccctat atgctgacta ttttaactac
      181 taactcatga ctaaagtcac gagtgtgcgt agctattttt taatcaaata gtttgaaatt
      241 aacatctaaa ttatcaatag gttcaattat ttcatgtgaa aaattatttc tgttcataat
      301 aatatcctcc ttataatttt aaattataaa tagtaaattt ataattttca atattaaaaa
      361 gataatatag actaataaat tagataataa acatacttaa gaaaacggat aaaatcaaat
      421 ataataactg tatattaaaa taacttaaaa aaattatttt attataagtg caaaatatac
      481 ctatttaaat aagataagag gggaggattt tatgtgtata taaaaggtgt aaatttagga
      541 ggttggttag ttttagaaaa atggatgacc tcaagtttat ttgaaggcac agaagctgaa
      601 gatgaatact atttaccaag acagctttca agagaggcat atgaatctag aattaagact
      661 catcgtagtg aatacatcac agagagagat tttgcaacga ttaaatctat gggatttaat
      721 tcagttcgta taccagtacc atactttatt tttggagatt gtgaaccatt cataggatgt
      781 gttaaagaac ttgataaagc atttgcttgg gcagataagt atgggcttag tatattgata
      841 gacttacata cagttccagg aagccaaaat ggatttgata atggaggaat atcaggtata
      901 tgtagctggt cacaaaatcc agaatatata gcgtttacat taaatgtatt agaaagactt
      961 gcaaaacgtt atgggatgag gcatgaattg tatggaatcc aaattttaaa tgagcctata
     1021 acagaaagaa tgtggaacat aatgaatgtt ccaaatcggt ttaaggctgt agataaggag
     1081 atggcaaagg ggagcaaacc taattcatta gagtttttac gtgattttta tataaaagca
     1141 tataaggtaa tgcgtcctta tatgagagag gaaaacgtta tagtgtttca tgatgcattt
     1201 gaatcaaaag catggaaaga ctttatgaga gaggaagaat ttaaaaatgt tgttctagat
     1261 acacaccaat atttaatgtt agctgaagca gatggatgtg aacaaagtat tgatagctat
     1321 ctcaaatata ttagagaaaa ttatgctaaa gatattttac aaatgcaaaa atattttcct
     1381 gttatatgtg gggagtggag cttatttaat tcatatgctt gtggtataga tacaaatgga
     1441 ggtcaatcac ctctaaatgg gattgaatca aatatagata aattatcaaa agacgataaa
     1501 agagaattat ataggaagat agcaaaagca cagcttgatg catggagaaa tggaagtggt
     1561 cactactatt ggaattataa gttattacta gatacagtta atgaagaagg ttggatagga
     1621 tgggatagtt gggacctagt caaatgtgta gctcaagaat ggtatcctat agaatattaa
     1681 actaaaattg gaggaaaaga tatgattaaa aaccctatac ttccaggttt taatccagat
     1741 ccttgtattt gtagaaaggg agatgattat tatcttgtag tttcatcttt tgaatggttt
     1801 ccaggtatac ctgtttatca ctctaaagac ttaaaaaatt gggagttata tactcatatt
     1861 ttgacagatg aaacaaaaat agatttgaag aagcttcctt catctaaagg aatttgggca
     1921 ccctgtttga cttattgtga agaagaagat ttattttata tagtttatgg aattatgaac
     1981 tctatgaatg caagatattt tgatgttgat aattatttaa ttacatcaaa agatataaag
     2041 ggagagtgga gtgaaccagt atatctacac tcatcaggtt ttgatgcgtc tatttttcat
     2101 gatgatgatg gtaaaaagtg gattgcatca ttagactggg agacaagaga aggatatgaa
     2161 aaacctggtg ttatatgttt agtggaatac tgtacaaaaa agaaagaaat agtaggatat
     2221 ccaaagagaa tatggtcagg gggaactgat agaggttgta ttgaagcacc acatataaca
     2281 aagcgtggag attactatta tataatgtgt gcagaaggtg gaactggata tggtcatagt
     2341 gtaactatgg gaagggctaa aaatatatgg ggaccttatg aaaaagattc aatgaatcca
     2401 attgtaactt caattccagg cgatttttat gaaagacatg accctgacca tctaaagcct
     2461 aaatactata acccagaatc aaaacttcaa aaatctggtc atggaagcta tatagaaaca
     2521 acatcaggtg aagtatattt agttcatcta acatctagac catttgtacc agagttaagg
     2581 tgtactttag gtagagaaac agctattcaa aaaatgaaat ggacaaagga taattggctt
     2641 cgaatggaaa atgaaagtaa tttggcaaaa gaatacgtat cagaaagtaa actagaagaa
     2701 catttagttt catctatacc aagttttgat gactttgatt caaatgaatt aggtttacag
     2761 tactatgctc ctaggatttc accattatca tttgcagatg ttaagtctag accaggatat
     2821 gtaaggatta gaggacaaga atcaagaaca tcattaaata aagtgagcat attggcaaga
     2881 aaattaactt cagtatatgc aagaataacc actaagatgg agttttaccc agaggtacat
     2941 cagcatagtg cgggtttgat aatgtattat gataatatga attatataaa tttaagaaag
     3001 tattatagtg aaacattggg tcaaagtgca ctatcaataa tacatcttga aaatggagag
     3061 aaaacggaat ttttaaatac taggatacca ataaaagata taccaatata tcttcgtctg
     3121 tatatacaag gtcgtaagtc atattttgaa tggagttatg atgaaaaaaa ctaccagaga
     3181 ataggaaagg tatttgatac aactaagttt tcagatgagt actgtaaata tggagaattt
     3241 acaggtacgt ttataggatt aacttgtgca gatcgtgtaa agcataaaca ctatgctgat
     3301 tttgattttt ttgaatatat agtagatgaa tcaaaagatg tcgattaata aaatcattac
     3361 taaaattttc agagcaaagg taaatcttat gctctgaaat aagaaacatt agaaggcaaa
     3421 tcttacaaaa aggagtatgg tattatgaat acagaagtta atgttaaagc aactacgatt
     3481 agatatgaaa agatttcatt ttttgaaaga atttcttatg gttgtgggga tttggggtgc
     3541 aatatcatat actcagctat gtcagcattt ttgctgtttt attatactaa ttatgcagat
     3601 gttagtgcag cagctgtagg tagtattatg cttgtatcta ggatactgga tgggtttagt
     3661 gacttaacaa tgggaattat agtggataga actaaatcca aatacggtaa ggctaggcct
     3721 tggattttga gaatggcgat tccttttgct atagcagcag tattattatt ttctgttcca
     3781 tcaaatcttg gtatcacttc taaattaatt tatattttta ttacatataa cttagtttct
     3841 actgttattt atacagcaat caatgtaccc tatgcaactc taaattcact tataactcaa
     3901 aaccagtatg aaagaggagt attaagtata tttagaatga tattagccac ttgtggtacc
     3961 ttactaataa atggacttac actacctcta gttgaatact ttggaaataa tttatcagca
     4021 tggactaaaa cattctttgt atttggaata gcatctataa tggtattttt tataacattt
     4081 actggaacca aggaaagagt aaaagcagtt aagcaagata ggaatgaagt aataccattt
     4141 aaaataggta ttaaatcttt atttagaaat aagtactgga tacaaataac attatgttta
     4201 gtttgcatat ttattgtatt tgcgataaat ggtggttcat ccgtatatta tgcaaagttt
     4261 attttgggag atgaaaaatt atttggtcct ataaatatgg tttcaaatat atcccaaatt
     4321 atagctatgt ttatggttgc tccttttata aaaaaatttg gaaaaagaaa tgtattaata
     4381 gtaggttcaa taatattaat atcgtcaaat gttatgttta taatagttgg acaaaactat
     4441 ataggagtaa tatctgcaag tgctataaag ggaataggaa gtgctggaat agcatcaaca
     4501 atgtttgcta ttgtttcaga tactattgaa tatggagaat ggaagactgg atatagaact
     4561 gaggggctta taaatagtgc atctagtttt gggtttaaag tgggaaatgg attaggttca
     4621 gcaatattag gtgcagtatt atcaattggt ggttatgtag gaacatcagc tactcaaagt
     4681 gatttagcta tagtatcaat aaaagtatgt tttatatacc tacctatatt tataacaata
     4741 ttacaaatta tcataatgtc tttttataag cttgataaag aatatagtac tatacttaat
     4801 gaattaaata ctaaataatg aaaaagtttc ttataaagtc ttaagtttaa ttaaggtcta
     4861 ttgtaaatgt tccctataaa aactattata tatttatgat tattgaagaa tttttagaga
     4921 agcgaataat aaaaatataa gaagacttta aatgatgaaa tggttggttt tttagaagtg
     4981 atttaataag ttattgttat ttaaagcatt ataagtggac aattaatttt taatttatgg
     5041 agatgatatt taacaattag aagtaatata taatatgcac taagaagcaa tttttcaact
     5101 atttatgaag gtggtggtac aagaaaagta tcaccttttt tttgttatac aaaaaaacag
     5161 ttgacttttt atatgaaccc cttctataat gttactgaaa ttaagtaaaa tgattgaaca
     5221 aatgtaaaga taattgaaaa gcttgatttt ggaggaaagc aaatgaaaaa aattggagac
     5281 ttaagattaa tgatgaagtg ttgttcactt tattacgaag ataatttgaa tcaacaggaa
     5341 atagcaaatc aattgggaat atcaagacca acaatatcaa gaatattaaa agaagctttt
     5401 gaacaaggaa tagtaaaaat acagatagtt gatgttttga aaaatgatta ccaaaaaata
     5461 gagagaagtt tggagagaaa atataaatta aaagaagtaa tagtagtaga tgataaacaa
     5521 gatgcactaa cacaaaaaca agaactagca agagctgtat ctgaatattt aactagagta
     5581 gtaaaggaaa atgatataat aggtgtttca ataggaacaa cactaaaaga aataccaaga
     5641 tatgtggaaa aaagtaattg taaaaatgtt acatttatac ctctattagg agggattgga
     5701 gacaatgaaa tagatattca tgcaaatcaa atagcagtaa gtttagcgag ggtttttgga
     5761 ggtgatttta aattattaca tgctccagct gttatgtctg acttgtctac aaaagagaaa
     5821 ctttgcaaag acgaaaaaat taaagaagta ctagatttaa tagataaaac aactatagca
     5881 attgtgggta taggaaatcc tatgagttta aactcaacaa taatggcttc tggatacatg
     5941 aatgaagcag atatagaaga tttaaaaaaa tacaactcaa taggtgcaat ttgtttacaa
     6001 gcctttgata aagaaggaaa aacttctata cttgaattta atcaaagagt attaggagtg
     6061 aaactggaag atttaaaaaa gataaaaaga acaataggtg tcgcttcagg agatgaaaaa
     6121 atagaggcaa taaaggcatc attaaaagcg aaatttataa atagtttagc aattaatcac
     6181 agtttagcac ttaaattatt agaagattgt gactaataga aagatagata aaagttaaca
     6241 ggagggaatg tatatgtcaa tatcaaaaga aacattgctt gaaatgtata agagaatgaa
     6301 tcaggctaga aaatttgaag agaaagttag ttggtttttt gcaagaggta tggttcatgg
     6361 aacaactcac ttatctgtag gtcaagaagc gtcaagtgtg gcggctgtaa tggctttaga
     6421 aaaaggagat ttagtatcat taactcatag aggacatagt caatttatag gaatgggaat
     6481 agacctaaat aaaatgatgg ctgaacttat gggtaaagaa actggatttt gtaagggaaa
     6541 aggaggctca atgcatatag cagatattga gtcaggtaac ttaggagcaa atggagttgt
     6601 aggtggaggt cttacaatag ctccaggagc tgcacttaca caacagtata aaaaaacagg
     6661 caaaatagtt ttatgtagtt ttggtgatgg agcatcaaat gaaggtactt ttcatgaagg
     6721 aataaattta tcttcaatat ggaaattgcc aataatattt tactgtgaga ataatttata
     6781 tggtatgtca acaagcataa aacgtcatat gaatatagaa agtattgcca ctagagcagc
     6841 ttcttatgga atagaaggaa tatcaataga tggatataac ccaatagaag tatacgaaac
     6901 agtacaaaaa gctgctgaga agtgtagaag aggagaagga cctgtattaa ttgaaagtag
     6961 aacttataga tggttaggtc attcaaaatc agatgcaaat gtatatagaa caaaagaaga
     7021 aatagaatca tggaaagcaa aagaccctat tgaattttta aaaaattatc ttatagaaaa
     7081 taatctatct aatgaagatg aattagataa gattcaagaa tttgcaaagc aatcaataga
     7141 agatgcagta gagtttgctc aaaatagccc aaatccaaaa atagagtctt tattagagga
     7201 tgtatatgca gactaagaat ggtaaaggag gaaaataaaa atgagtacaa gggaattaac
     7261 atatgcacaa gcaataaagg aagcaatgtc agaagaaatg agaagagatg aagatgtaat
     7321 atttatggga gaagatatag gaatatatgg aggagcattt ggtgtatcag ttggtatgat
     7381 agatgaattt ggaccagaaa gagtaaggga tactcctata tcagaagcag ctatagcagg
     7441 agcggcagca ggtgcagcag caactggctt aagacctatt atggaagtaa tgtttatgga
     7501 ctttgtaaca atttctatgg atgcaattgt aaatcaagcg gcaaaaatga gatatatgtt
     7561 tggaggaaaa gcacaagttc caatggttgt tagatgtcca ggaggttctg gaactggttc
     7621 agcagagcaa cattcacaaa gtttagaagc ttggttttgt catgtaccag gagtaaaagt
     7681 agttgcacct tctacaccag cagatgctaa gggattgttg aaagcagcta taagagataa
     7741 taatccagtc atatttgttg agaataaatt gttatacaga aaaaaaggtt ttgtgccaga
     7801 agatgattat gtaattgaaa ttggaaaggc agatattaaa agagagggta ctgatgttac
     7861 agtaattact tatggaagaa tgttacaaag tgttgaagaa gcagcagaga ctctatcaaa
     7921 agaaaatata aatgttgaaa ttatagattt aagaacttta tatccattag ataaagagac
     7981 tatagtaaag agtgtatgta aaactgggag agttttaatt tgccatgaag cagctaagac
     8041 tggtgggcta ggtggagaaa tatcagccct gataacagaa agtgaatcat ttgattattt
     8101 agatgctcca gtaaaaagaa tttgtggaaa agatgtgcca ataccatata atccagagtt
     8161 agaaaaagca gttgtcccaa gagttgatga aatagaagaa gcaataaaat ctttaattgt
     8221 tagataagga gggatagata tggtggcaaa taaaataaaa gccacaccag cagctagaag
     8281 tcaggcaaga aaagacaata taaaattaga taggctgatt ggaagtggag aaaatggaag
     8341 gattcattta gtagatgtgt taaattattt aaaagataat aaagcaaata ctactccttt
     8401 agctagaaga atagcagaag atttaaatat agatttagaa actattgtag gtactggata
     8461 taatggaaag ataagaaagt gtgatgtgga aaaattaact ggaaaagaaa ctattgtatc
     8521 aactaataca tctaaatcta gtgagaaaaa agagctgaaa attgaaaatg aaaattcaag
     8581 aatgtttaac acagtagaag gaatatttga aaagccaaat ccaatgagag ctactgtagc
     8641 aaaacgaatg tcagaaagtt attttagtgc tcctgtattt acattcaata tagaagtaga
     8701 tgctacagaa ttgaaggtac ttagagcaaa gttaatcgac acagtaaaag aatcaactgg
     8761 agtaaaatta actatgacag atttaatagt aatggcagta tctaaaatac ttccaaatca
     8821 tcaagcctta aattcagcat ggacagatga gggtatattt agatataaag atgtaaatat
     8881 agctattgca gttggtttag atgaaggctt atatgttccg gtagtaaaaa atgcaaacaa
     8941 aaagtcttta aaagaaatag caaaagaaag caaagaactt gcggaaaaag taaagacagg
     9001 gaaacttatg ccagcagacc aagaaggtaa tacatttaca ataagtaatg ttggaatgta
     9061 tggtataact acatttacac ctataataaa tatgccttca agtgcaatct taggggtagg
     9121 tgctacacaa gataagtttg ttccagtaaa tggagaggct aaaataaaac ctataatgaa
     9181 cttatcatta acatcagacc atagagtaat agatggaaca gtagctgcaa aattcttaaa
     9241 agatttaaaa gaattgttag aaaatccttt atcaatgctt gtataggttt tgatatttcg
     9301 ttactgatat aaatagtttg aatagattat attattataa ttgtttcagt aaatttaaag
     9361 cttttatata ttaagaatta tttttaacag taactatatg tgaatatgat ttgcttaatt
     9421 aaaatatatg aaaataaata ggaggagagc ctatgtcagt agaagtaata atgccaaaag
     9481 caggagtagc catggaagaa ggtactatag tatcttggct aaagcaagaa ggcgaagaag
     9541 taaagattgg agaacctata ctagaaataa caacagataa agttaatatg gagatagagt
     9601 cagaaggaga aggtacactt gctgtaatca tacataaaga ggaaggtgaa gtattaccag
     9661 tatttacagt aataggtgta atagcagaaa aaggggaaaa tcaagaggaa gtaaaagcta
     9721 aatatttatc tggaaatgtt tcaaaagaag atatagttga agagaatcaa aatatagaat
     9781 ttaaagaaga aaaaataaac aaaaaagagt gtaatcatga ttatgatgta gtggtaatag
     9841 gaggaggacc tgggggatat ttatcagcat taaaagcagc tcttttaggt ggaagagttg
     9901 ctttagttga agaaaatata ctaggaggta cttgcttaaa tagaggttgt atccctacaa
     9961 agacttatat aaaaacagca gaaatattag aagaaattga ccaattatca aagagaggtg
    10021 taaaagtaac tgtagataaa gaacaggaca ttaagaaggc cataaaatat aaaaatagag
    10081 tagttaaaaa acttacagct ggtgttggcg gattattaaa aagtagagat gtagatgtgt
    10141 ttaatcttaa agctagtgtt aaagaagagc ataaagtaat tttatcagat ggaaaagttt
    10201 tagatacaga aaatataata attgctacag gttccaaagt aaggatatta cctataaaag
    10261 gaatagaatc aaatttaata ataactagta cagaagcatt agatttggaa acagtgccag
    10321 aagaattagt aataattggt ggtggagtga ttggttgtga atttgcagag atattcaatt
    10381 caagaggttc taaagtaact atagtagaaa tggaagatag agtaatccca agaatggata
    10441 aagagttaag cgaatcttta aaatattctc ttagtaaaaa aggtataaat gtattaacta
    10501 aaaagaaagt ttctgaattt aaagaagaag gaaataacat attagtgtgc attgaaggtg
    10561 aagagccaat aaaagcagat ttatgtctat atgctatagg aagagaagct aatctttctg
    10621 gcatagagga cttagatatt aaaatagata aaggttcaat agttgtaaat agtaaaatgg
    10681 aaacaagtat accaagcata tatgcagtag gtgatgttac tggaggtgta atgttagctc
    10741 atgctgcttt taaaatggga gaggtagcag cttcaaatgc tctaggcgtg aataaagaag
    10801 ttgacttagg tgcattacct agttgtgttt atacaattcc agaagtagca tcagttggta
    10861 ttacagaaga ggatgctaga aaaaaatata atgtaaaagt tggtaagttt aattttgctg
    10921 gaaatggaag agctttagct tctggtcaag aacaaggata tgtaaaagta gtagcagatg
    10981 ctaaatatgg agaaatttta ggtatacata tgtttggatg tggtgtagca gaacttataa
    11041 atcatgcagc atcatttaaa gcgttagaga tacctactga tgaagcaagt gagttgatat
    11101 ttggtcatcc atgtacttca gaagctttaa tggaagcttt ggcagatgta aatggagaat
    11161 gtttacactt acctaaaaaa taaatctaaa cataaattat taatttaagt ctattattaa
    11221 tattaattta tatcataaaa ttttaaaaca cttacttagc catacccctt attatgcaaa
    11281 taatttattt gcataataag ggatattttt tatggaaaaa tatagaatat agaatccttg
    11341 tagtttttgt tgtacaaaaa agatagtaat ataaaataac attatcattt tagaatgatt
    11401 tcaattgtaa ttaggaaaag tgattttttt agattaaaaa aagtattatt tgtaaaatat
    11461 aaaaaaaaat ttcttaatat ttgaataaaa gaatagctta atttaaatgt tattacttta
    11521 taaaaaaata ataagtacaa aaaaaacaat atatggcata taagttgcta cataaataat
    11581 aaggagggaa caattataaa tgaggcaaag aataaaaaac ttaattgaaa atgaagataa
    11641 gaaaaatcct ttaacagatg aagcgatttc aagtaggtta aatattcgaa gagaagatgt
    11701 tacctttttg agaaatgagt taaaaataga agattcaaga caaagaagaa aagttgtttt
    11761 aattaaagct ataaaagata ttttaaaaga agaaaaaact ataaataaaa atgatataac
    11821 aagaagatta aacagcattg ggtttacagt atcaagattt acagtcatac aatacttaaa
    11881 agagattcaa gattctggtg acctaaaact tgataaagag agtgatgata aaaaagaaga
    11941 aataatcaat aatagagaaa ataaagatat agcatttgat aaactcatag gtagtagtgg
    12001 tagcttaagt acaattataa aactagccaa agcagcaatt ctttatccac ctcatggtct
    12061 tcatactatt attatggggc caactggtgt tggaaagagt gagttagcag agtgtatgta
    12121 taaatttgca gtagaatcat ccagattccc taagaatgca ccatttatag tttttaatgc
    12181 agcagattat tcagagaatc cacagctttt gctatcacag ttatttggac acgttaaagg
    12241 tgcttttaca ggagctgatg agaacaaaga aggattagta tcaaaggcag atggaggaat
    12301 attgtttata gatgaaatac atagattacc tcatgaaggt caagaaatac tatttcaact
    12361 gattgataaa ggtatggtca gaaagttagg agaaacaaga ctaacacata aaatagatgt
    12421 aatgattatt tcagcaactt ctgagccaat agattctcat ttacttaata catttaaaag
    12481 acgtatacct gtaacaattg aaataccaga attagttgca agaccattaa atgagaggtt
    12541 tgacattata aataatttct tcttaataga agctcaaaga atgggagcaa acatacatat
    12601 aaagtcagat gtattaaaag ctcttatgct ttacgattgt ataggtaatg taggtcaact
    12661 tagaagtgat attcaagtag cttgtgctag gggactatta aaccaactta caaacaaact
    12721 aaaagaagta aatataagca tatcagatgt acctggatat gtaaaacaag gtcttataaa
    12781 aatcagaaat tgtagaggaa aaatagaaaa ttatgtagat ggggatttaa ttatagactc
    12841 aaatcttcaa ggtgagatag aaaagaaaaa tgaagatata tatacttttc cagatgaaat
    12901 atacaaactt actgaaagaa gacatattga tttattggaa caaggtttag attttgatgt
    12961 tataaataga atcattggag gagaattaga aagttgcatt caaaaataca taaaacaagt
    13021 taaaaaagtt tctattagta acaatcttcc agatataagt ccaattgttg gaaaatatat
    13081 cgtagagcta acttatgaag taatcaaaat agcatcacaa tacctaagtt cactagaacc
    13141 gaatctacat ttatgtttag cagttcacct aaaagcagct tttgagagat taaaagaagg
    13201 aaaagtaata tcaaatgctc atttgaaaga aataatagga aattatccac tagaatattc
    13261 tgtagcagaa aaggtagctc aatatttaaa ggaaagatat aacataaact taccaaaaga
    13321 agaaataggt ataatagcaa tatattttaa aatgagtagt agaagagata tgtctgaaca
    13381 aaaaaagata ggcgtacttc ttatggctca cggaagagta gcatcttctg tatgtgaggt
    13441 tacaaataaa ctattaggaa ttaatcacgc aaggtattta gatatgccat ttgagaagaa
    13501 gccggaagaa atgattgaag aagctactac aataataaaa gatattgatg aaggtagagg
    13561 tgtgattata ttagtagata tgggttcact ttcatatttt ggagatatta tttctggaaa
    13621 gactggaatt aatataagga caatatctag atttgataca ttgctttcta tagaggttat
    13681 acgaagagca gttttaccag atttaacaat agacgagata gttgatgaag ttaaaggcat
    13741 agagccacaa gtaaaagaaa aggttagtaa atgtaacaat acaaaagtag attttagaaa
    13801 acctataatt ttaacattat gtattactgg attaggggga gcttgtaaga taaaaaaaat
    13861 cttagaggaa aatattaaaa gtataactga aaaggttgat atagaaccta taggtatgat
    13921 tgaatatcca agtcttgatt tagagataaa acaaataagc aatgataaaa atgtaatcgc
    13981 catagttgga acaattgacc ctcagatagc aaatatccct ttttttagtc tagtagacat
    14041 aaatgataaa gcaaagttaa atcaaataaa taacctaatt gatacaaatc aaattggtga
    14101 aacaaataaa aaatatgaat tatcagattt aatacataaa gaagatatat ttgtggattt
    14161 acaggttaaa tcaaaagaag aagttctaaa atatatgagt aaaaaactta gagagaaagg
    14221 ttatgtgaca aaaaatttct ataaaaaagt agtggaaaga gataacttat ttccaactga
    14281 attatcagat gaaatagcaa tacctcacac agatggaata gatgtaatta gaccagctat
    14341 aagtatagcc atcttaaaga agcctattgt gtggagtaaa agtaaagtaa aaataatact
    14401 tttattagct gtagaccaaa agtgttttaa tccattaagc actctactct catttataga
    14461 aacagatgaa tttaagaaga taaaaaacat taaagataga gattttatta gggagatgat
    14521 attagatgga gtcaatgaaa ataattagta gcaatttaat ttttaaaaat attgaagtgt
    14581 ctaacaatga agatgcatta aagtttttgg gacaacgttt gtttgacgaa cagtatgtaa
    14641 aagaaagcta catacaagct gttgtagcaa gagaaaaaaa gtatgctaca gggttaccaa
    14701 cagaaatata cggagtggca ataccacata cagatatagt acatgtaaat gagccaggaa
    14761 tagcaattgg aatactgaat aaacctgtaa aatttataat gatgggtaca gacgatactg
    14821 aaatggatgt aaaagttgta tttatgttag cagtgaaaga gccacaagaa caattgcaac
    14881 tattagaaaa acttatgact atatttcaag ataaaaatat actaaataat attgttaact
    14941 taagtgaaga aagtgtgagt gatttattaa actctaaatt gaaaaattaa acatgtaaag
    15001 tatattaaaa atgtaaaatt aaacatgcaa agtatgttaa aaaatataaa aagattatta
    15061 aagatttcta actatagata tctttaaaat aaaataattt caatgggggt gactaatgtg
    15121 gctaaaaaga tattagttgc atgtggaaca agagtatgta cttcaacaat tgctataaac
    15181 aaattaaaga aagcacttca agacattggt aaattggata tggttaatat tacacaatgt
    15241 aaagtagtag aagttgcatc aaaagcacct gattatgatt taataatttg tactacacaa
    15301 gtatctagta gtataaaaac accagtgata aatggattac cttttttaac tggtgtcgga
    15361 atggataaat taatcaatga tgtattagaa gagttagaat tataattaaa aaaattaagg
    15421 aacatggtct ctaaaatcat aagttttaga gacttaaaat taaataatgg agggtcttta
    15481 tatggagata ttaaatttca ttgttggtct aggtgcacaa gtaatgatgc caataataat
    15541 atgtattttt ggtttgatat taggtacaaa actaggaaaa tctttaagag ctggtttaac
    15601 tgtgggagtt gggtttatag gtcttaacac tattatagct ttgctaacag acaatttagg
    15661 tccagctaca caacaaatgg ttaagaattt agggctaagt ttatcaataa tagatgtagg
    15721 atggccagta gcatcagcta tagcttttgc atcaacagta ggggctttaa ttattccaat
    15781 aggtcttgtg gtaaatatag ttatgctaat tactaatact actcaaactg ttgatgtaga
    15841 catatgggat tactggcatt ttgcttttac aggagcttta gtggcagggg ctactcaaag
    15901 tgtaatgtgg ggagtatttg cagcagtagc aaatatggta attgtattgg taatggcaga
    15961 tttaactgct ccaggtatag aggaatattt aggtatgcca ggtatatctc ttcctcatgg
    16021 atttacacag gcctttgttc caattgctat agtagtaaat aaattattag acctaatacc
    16081 aggcataaat aagattgaga taaatgctga tatattgcag aaaaaatttg gattatttgg
    16141 agaaccttta ataatggggt ctgtaatagg tgtaataatt ggtattgctg cgaaatatga
    16201 tataaaagga atattacaat taggtgtaac tatgggagct gtattaatat taattccaaa
    16261 gatggcagca ttattaatgg aaggattatt accagtatca gaagctgcac aggaatttat
    16321 tgagaagaga tttaaaaaca gaggcaagat ttatataggc ttagattcag cagtaggaat
    16381 aggtcatcct gttacattat cagttgcact agtgttggtt cctttgacta tacttatagc
    16441 agctatattg ccaggaaata aagttttacc atttgcagat ttagcagtaa ttccatttgc
    16501 acttgtatta atcgtaccaa ttacaaaggg aaatgtgttt agaacattaa taataggaat
    16561 aattataatt acttctggat tattaatcgc aactaactta gctccattat ttacccaaat
    16621 ggctttaaat gctagtttta aaatgcctga aggagcaact atgatttcaa gtatttgtga
    16681 tggtgcgaat ccattaagtt gggtatttgt aaaagttatg aactataaag ttattggagg
    16741 agtaattttt ggagttatag ctttaggaat ggctatttac aataggaata gaataataaa
    16801 tgaaaataaa aagctatcta tagaagaata aggttaaaac aattttatta aggagtgtat
    16861 aggttatgaa aaaatataaa tatgattcta aaaggtactt actcagtgtt acaataccag
    16921 gattttttat gattttaata ttgatttatg cactgtttaa taactataca aattttaatt
    16981 tgaatatata tagtttgtta ataattgtct gtacttatgg tatattcaat acttttatat
    17041 catcaagtaa tcctaaaaaa attattattg atagcaaatg tatacatttt acctcattta
    17101 tgactacaca taagtatgaa attaaagata tagaaaagat aagaataaga gaattttata
    17161 ataaaaaaat ttatctaaaa attaataatg gaaacctttt taaaggtagg tattggataa
    17221 gaacaaatat gtttaataat agtatagcat tatatagcta tttcattgag ttggaagagt
    17281 gcttatatcc agattcacta aaatttagaa ataaaaaatt tgagaataag aacatataaa
    17341 aataaaaaat tgaattgaag cctagcttaa tcttttttga taaaatataa gtttgaactt
    17401 tatactaaat ttttagaatt ttcaatcaag acaataacat aatagctaag caattagaac
    17461 acaattaaga tgtataaggc atgtatatga tgaatgggag gatttaatta atgttattag
    17521 agaaattaag aaaagaagta ttacaagcat ctttagacct tttaaactat aatttagtga
    17581 cattaacagg aggaaatgta agtgggagag atgaacaaac tggctatata gcaatcaccc
    17641 caagtggaat ggattataga aatcttacac caagtgatat tgttatagta gatgtagatg
    17701 gaaatattat agatggaaaa tggaaagcat cagtggattt atcagaccac ttgtatatat
    17761 ataagcatag agaagacata aatagtataa ttcatacaca ttctacatac tcaagttgtt
    17821 ttgctatttt aaatgaacct atagaatgct caagtacaac tcttgcaaat gaagtagggg
    17881 gttcagtacc agttgcaaaa ttttcaccac caacatctaa aaagatggga aaatgtgtta
    17941 ttgaagcaat tggtgacaaa agagcatgtc ttttagcaaa tcatggcgta attgcagttg
    18001 gtccatctgt aggacatgct cttacagccg ctgtaatgtt agaagattca gcaaaagtat
    18061 attacttagc aaaatcaatt ggcacaccag tgctactgcc tgatgaagaa attcaaagag
    18121 cgagagatgt attttttaat gtctatggtc aggataaata aattagataa aattttaaaa
    18181 gtaatatgaa aatatagata ttcaatgata ttaaggagat ttataatgat ataataagtt
    18241 taatagttaa gaagtaaaat atgaaatgta atagtatata aattcattta agactaaaaa
    18301 taataagata aaataaaaag gagtctgtat ttctatgtat tacttattaa acaaaagcac
    18361 aaatccttac tttaatttgg cattagaaga atatctattt ttaaatgata aatataatga
    18421 tgatattata atcatatgga gaaatgaaga atccattttt ataggtaaaa atcaaaatcc
    18481 atatcaggaa gtatatcatg atgttattga aaagggagaa attcctattt taagaagaat
    18541 atctggagga ggaactgttt atcatgactt aggtaatatc aatatgtcat tcatacaaaa
    18601 agataggcaa cttcatgaga tagatttttt ggagcatact aagtttatgc aaaagatgct
    18661 ttcaacctta ggactagatg tatctataac tgaaagaaaa gatttatttt taaatgggaa
    18721 aaaaatttca ggttctgcac agtctataaa aagaaaaaat tctctttatc atggaactct
    18781 tctttacgat tcagatttaa ataaattaac taaatattta aattcaaata aagcaactga
    18841 atcaaatgca actaaatctg tttcaagtaa agttacaaat attaagtttt tactcgaaaa
    18901 agatataaat tactttttag attattgtgt tgaatattta aaatataata taaagaatat
    18961 aaaagaactt gaattggatg aagaagatat taaaagtgta tacaatatag gagaagataa
    19021 atataaaaag atagagtgga catatggtaa aacgccgaaa tttcaagtag tgctaccatt
    19081 tgataatgaa agtaaaataa atatacatgt taacagatgg aaagtatcaa aattttttat
    19141 ttcttatgat gataatgtaa ttaatatgga caagttgtta gatttgaatt tctttaaaga
    19201 agaaataaaa gagagtattt tagaaaatta tccacattac atagatttaa tcaatttaat
    19261 attttaatat aaaacctcta atttgataaa attgtcttat atcaaactag aggtttttaa
    19321 tattcttgca tattaacaac cattacaaaa ttgtaaaatt aaaaacaaca ctattgaaaa
    19381 atcaatatat atttgtttaa atatatgtgt ttttcattag caaatagaca ttaactattt
    19441 atacaactga aaatttaata tataattaat cagatggtta aaataaaaat attaaaagtt
    19501 ttaataaatg atggttaaaa ataaaatacg aggtgatacc atgtatagtg ttataattgt
    19561 tgcagcggga agcggaagga gaatgaactt agatataaac aaacagttca taaaattaag
    19621 agaaaaagaa attattgctc atacaattca agttttttat gaaaatataa atatagatga
    19681 aatagtggta tgtataaaaa aagaagaaga ggattttttt aaagaaaata taataaataa
    19741 gtataacttt aaaaatataa aaatagcata tggcggaaaa gaaagacagg actcaatata
    19801 taatggttta aaaaaattag atgaaaattg tgatatagta cttatccatg atggagcaag
    19861 accatttgtc gaccatagaa taatcaacga atctataaag gtagctaaag aaaaaaaggc
    19921 tgtggttgta ggtgttccag taagtgatac tataaagata gtgtcagatg gaacagtaca
    19981 agaaactcca gaaagaaatt tgctgtgggc agcacaaacc cctcaaacct ttgaatataa
    20041 tctcataata gatgcttatg aacaagcata taagaacaat tattatggta ctgatgattc
    20101 aatgttggta gaaaatatag gtcaaagtgt cactatggta atgggttctt atgaaaacat
    20161 aaaaataact agtccagaag atttaaatat agcagaacaa atattaaata tggaaaaaag
    20221 agatgaagtt aacagtagaa ggagaattat atgagaatag gattaggata tgatgtacac
    20281 aaattaacag aggatagaaa acttataatc ggtggtgtag agataccaca cgataaaggt
    20341 ttgttgggtc attctgatgc tgatgtattg atacatgcaa taatggattc tattttaggt
    20401 gctctagcat taggagatat agggaagcat ttcccagata cagatgaaga atataaggga
    20461 gcagatagta tgaaattatt agaacatgtg tataatctaa taacaagtaa aggatataaa
    20521 attggtaata tagacagtac tataattgct caaagcccta agatggctcc atatattgag
    20581 agtatgagaa gtaatatatc aaaagtttta aacacagaca ttgataatat aaacataaag
    20641 gcaacaacag aagaaggtct tggttttaca ggagcaaaac agggaatagc ttcacaaagt
    20701 atttgtttat tattgttgac aagtcagaat aattaatata ttattagtaa taagtttaat
    20761 ggatatcaag taataggcct atatagaata tctataatgt atgaatttaa gtgaaattaa
    20821 tataaatata aaattagcta tgataaagaa atagtaaaat gatgaaatct tcacagagag
    20881 aaaacggtgg tgagagtttt caagaggaag tctttgaacc tgtcttttag cttaaaggta
    20941 taaaaatctt tacggtagga accgttatat tcccaaaaga gagctattca tatagctaac
    21001 tagagtggta ccgcggaaat taaacctttc gtctctatac ttgtatagag atgagaggtt
    21061 ttttatattt tcaggaagtt aatattcagg aggaatctat taatgaaaat gtcaaaaatg
    21121 tttatgccga cattaaaaga aatcccagca gatgctgaga ttacaagcca tcaattaatg
    21181 gttaggtcag gcatgataaa aaaaatgact tcaggtgttt ataaccaatt accaatgggg
    21241 ttaagagtgt tcaaaaaaat tgaacaaata attagagaag aattaaataa aaaagattgt
    21301 caagaaatac tttgtgccgc cttacttcct tctgaattat ggaaagagtc tggaaggtgg
    21361 actgctatgg gtgaagaaat gtttagacta aaagacagaa cagaaagaga gtactgtctt
    21421 gggccaacac atgaagaagc attcactgat ataataagac aagaaattac ttcatataaa
    21481 caattgccac tgaacttgta ccaaatacaa gtaaaatata gagacgagag aagaccaaga
    21541 tttggtgtta tgagaactaa gacttttaca atgaaggatg cctatagttt tgatgtagat
    21601 gataaaggtt tagataagtc atatcaagat atgtttgatg catatgtaag tatatttgat
    21661 agatgtggat tggagaatag ccctgtacag gcagattcag gagctatagg aggttctaca
    21721 tcagccgaat ttatggttaa gtcagaagtt ggtgaagatg aagttgtatt ttgtagtgga
    21781 tgtgattatg cagccaatgt agaaagagca gaatcttgta atctagtatc acaaaaagaa
    21841 gaaatgaaag aattagaaga ggttcataca ccaggagcag ctacaataaa agagttagaa
    21901 gaatttttaa aaacttctcc agataagttt gctaaaactt tagtatatga ggcagatgga
    21961 aaaacagttg tagtcgttgt aagaggagat agagaagtta atgaaatcaa agtatctaat
    22021 gctataggtt ctgttataga gtttgctctt gctacagatg atgtagtgag aaaagtaact
    22081 aatgcagaag taggatttgc aggtccaata ggtataaatg ctgactatgt atttatagat
    22141 aaagaaattg ttgaacaaag aaacatagtt gttggggcta ataaaactga gtaccatata
    22201 aaaaatgcta actatggaag agattttgaa ggaatagttg gagactttag aaatgttcaa
    22261 gaaggcgaca agtgtatagt atgtggtaag ccacttgaaa tagctagagg tgttgaagta
    22321 ggacatatat ttaaactagg aactaagtac tcagaatcta tgaatgcaaa cttcatagac
    22381 aaagatggaa aatcaaagcc tatagtaatg ggatgttatg gaataggtgt tgaaagaaca
    22441 gcagcagcta taattgaaca acataatgat gagaaaggta taatatggcc tttgtcagta
    22501 gctccatacc atgttgtgat agttccagca aatatgaaaa atgaagaaca aatatcaata
    22561 gctgaaaata tatataatga tttgcaagct atgggtgtag aagttttatt agatgacaga
    22621 gatgaaagaa taggtgtcaa attcaatgat tcagaattaa taggaatacc gatgaggatt
    22681 acagtaggta aaaatattaa tgaaggtaaa gtagaattta aacttagaca taaagaagat
    22741 aaagagataa ttgacataga agaaataaat gaaaaagtaa aggcagagtt tatcaggaat
    22801 aatgttaggt taggataata acttaaataa gatattgtat agataatcaa agttgtactt
    22861 tatagacacc attttatcta tatataagga tataaaatgg tgttttttta taaaacaaat
    22921 aaatgaggag gtaattgaaa tggcaaaaaa tgaaaaacaa tttgttgaag aaataacaaa
    22981 gatggaagat gattttccac aatggtatac agatgtaata actaagactg acttagttga
    23041 ttatgcacca gtaaaaggtt ttatggttgt aaagccatat ggatatgcat tatgggaaaa
    23101 gatgcaagaa tttatggata aaaaatttaa agaaactgga cataaaaact gttattttcc
    23161 attattaata ccagagagtt tattaaacaa agaagcagaa cacgttgaag gttttgctcc
    23221 agaagttgca tgggtaacac atggaggaaa taaaaaatta gaagaaagat tatgtgtaag
    23281 acctacttca gagactataa tatgtacaat gtatgcgaaa tggttaaaat catatagaga
    23341 attaccatat ctttataatc aatggtgctc agttgttaga tgggaaaaat caactagacc
    23401 tttcttaaga acatctgagt ttttatggca agaaggtcat acgttacatg aaacagcaga
    23461 agaagcacaa gaagaaacaa tacaacaatt agaagtatat aaagcgctat gtgaagaatt
    23521 acttgcaatg ccagttgtag ctggtcaaaa aagtgaaagt gagaaatttg caggtggtga
    23581 aagaacatat actatagaag ctatgatgca tgatggtaaa gcattacaat caggtacaag
    23641 tcacttccta ggtcaacact ttactaaggc ttttgatatt acttttgcag atagagaagg
    23701 aaatttagct aatccatacc atacatcttg gggagcatct acaagactta taggtggact
    23761 tataatgact catagtgata acagaggttt agtattacca ccaagagtag ctccaattca
    23821 agttgttata gttcctatag ctgctaaaaa aggaaatgta atggagactg ttgataaaat
    23881 atatgctgat ttaaaagcta agggagtagc tgtagaagtt gatgatagag ataactatac
    23941 aactggatgg aaatttaatg agtgggaaat gaaaggtgtt ccagtaagag ttgaaattgg
    24001 accaaaagat atagaaaata atcaagctat ggtatttaga agagatactt tagaaaagga
    24061 ttctatgcct ttagaaggat tagctgatgc tatatgtgat ttatttgatg ttatacacaa
    24121 tgatatgttt gaaaaagcaa gaaaacatag agaagacaat acatctatag ttgaaaatat
    24181 ggatgagttt agaaaagctt tagaagaaaa gccaggattc ataaagacta tgtggtgtgg
    24241 agatgcagaa tgtgaagcta agattaagga agaaacagga gcaactataa gatgcttacc
    24301 ttttgaacaa gaaaacttag gtcacaagtg tgtgtactgt ggaaaagaag cagatagtat
    24361 ggtagtaatg gcaaaagctt actaaaatac atttaaataa aaactggggt agaaagtatt
    24421 taatacttta tcccagtttt tttgtttttt atgagtaata aaatgtattt gtaactatgt
    24481 cataagataa gtcatagata cttatattaa aaagaatata atagagaact atttttaata
    24541 attacatatt aatgaaagca aaatattttt gttatataga ttttcaataa agcaaacaat
    24601 aaatataaat gaatattagt aaggagtgct tttaattttt agaaaataaa tgacttaaaa
    24661 gaaagattta tgaaattaaa actaggattt tctgatataa taaacatgtg tatttttaaa
    24721 taaaaaggat attattatta gatttgatta aaaataaact tgcaaaacaa tgtactagtt
    24781 taatattata gttatattga ataaaatatc aggaggaagt aaaaatgaat gtaagagtaa
    24841 ggtttgcacc aagtccaaca ggatttgtac atataggtag tttgagaact gctttatata
    24901 actatttatt tgcaaaaaaa atgggcggag aatatatatt aagagtggaa gatacagacc
    24961 aaagtagatt agtagaaggt gctatagaga atatgcttaa tgctatgaaa tgggctgggg
    25021 tcaaccatag tgaaggtgtt atattagatg atagtggaaa agtagtacaa aaaggagaat
    25081 atggtccata tattcaatct caaagattag atatatacca agaatatata aagcaacttt
    25141 tagatagtgg aaaagcttat tactgtttct gtacaaaaga aagactggat gaagtaagag
    25201 atgctcaaag agcagcagga gaaacagcta aatatgatgg tcattgtaag aatctttcta
    25261 aagaagaagt agaagcgaat ataaaagcag gaataccata tgttataaga ttaagattgc
    25321 cagagaatca tacaattaag tttacagact tagttagagg agatatggaa tttaatacta
    25381 atgacttaga tgaccaagta ttaatgaaaa cagatggatt tccaacttat cattttgcag
    25441 tagttgttga tgactatttg atgaaaatta cacatgttat aagaggagaa gaatgggtat
    25501 catctactcc aaaacatgtt tatttatatg aagcttttgg atgggaagca cctgtatttg
    25561 tgcatttacc aaatatactt aataaagaaa agaaaaaatt aagtaaaaga caaggtgatg
    25621 tagctgttga agactttaag aaaaaaggat atttaccaga gggattagta aactatgtag
    25681 cattagttgg ttggtctcct gaagataatc aagaattgtt tacaatggag gaattagaaa
    25741 aagccttctc tgtagaaaga gtatctaaaa gtggtggagt atttgatact gaaaaattaa
    25801 attgggttaa tcagcactat ataaaagatg gtgatgatgc ttatctaaca gacttagcaa
    25861 taccattttt aatagaagat ggatttataa cagaagaaga agctactaat aaatatgatt
    25921 tcttaaagag tatgatatca gtacttaaag agaaattaca atatgtaaaa gaagttactg
    25981 aacatgcaag tatatttttt ggagataaaa tagaggtaga aactgaagag ggaagagagt
    26041 tcttaagatt agaacatata cctactttaa tagatgcttt gagagaaaaa atagaaaaaa
    26101 cagaggtatt aaatgctgag tttgttcaag ctatgcttaa agaaatacaa aaagagtaca
    26161 aaataaaagg gaaaaattta tttatgggct caagaataat tttgacaggg caaatgcatg
    26221 gtccagattt accaaaagta atggaagttt taggaaaaga aacttgctta aatagaatag
    26281 cttatgtaaa aaataatata ttatagtcat aaaagtccgc taatttagaa gcggactttt
    26341 tttgtgttag tatttggtga aaatatctgc ttaagaaaat gaaggtattt aaggtaataa
    26401 atttaatata taaaaagcaa agcaaaaata taaataaaat atgaataata aactaataaa
    26461 atattaagca tagaagaagg gaatctatta ttttagtttg atttaattat taagggggta
    26521 attactatgt atagtaatat tgatgatgtt aaaaaggaat taaaggagct atgcttagaa
    26581 tatgttacaa ttttagaaaa attaaaagat gaaaaaatga ttacagaaga aacttttgaa
    26641 aagtgctctt ctcaaaaaaa aatattttta gaagaacaat agaggatggt aatagtatta
    26701 ttattatgta gtttgaaaga tagtacgaaa aatgatagta atactattat ttattgcaat
    26761 tttcaactat aatataatat ataatgttaa gaagataatt tataaaaata cagtgaggtg
    26821 atgagtgtga aagtttataa tacattgact agaacaaaag aagaatttgt tccattagaa
    26881 gaaggaaagg taaaaatgta tgtgtgtggt ccaacagttt ataactatat acacataggt
    26941 aatgcaagac catttataat atttgatact ctaagaaggt atttagagta tagaggatat
    27001 gatgtaactt atgtacaaaa ctttacagat gttgatgata agattataaa tagaagtcat
    27061 gaggagggaa tatctcctga agaagttgcg gctaagtata taaaagaata ttttgtagac
    27121 tgtgatgggc taggaataaa aagagctact gttcatcctc aggttacaga taatatacaa
    27181 cagattatag agtttataaa agagttggaa tataagggat atgcatatgc agtaaatggt
    27241 gatgtatatt ttgatacaaa taagtttgaa ggttatggaa aactttcagg tcaaaaacaa
    27301 gaagatttag aggcaggggc tagaattgag gttaatgacc aaaaaagaca tcctatggac
    27361 tttgttcttt ggaaggcaaa aaaagaaggt gagccaggat gggatagccc ttggggagaa
    27421 ggtagaccag gatggcatat agaatgttct gttatgtcta agagatattt aggtgaaaca
    27481 attgatatac atgcaggtgg gcaagattta acattcccac atcatgaaaa tgaaatagct
    27541 caaagtgaag ctagaagtgg aaaaatattc tcaaaatact ggatgcataa tggatatata
    27601 aatataaatg atgaaaagat gagtaaatca aaaggtaatt tctttacagt aagagatata
    27661 tcaaaattat atgatttaga gatagtaaga tttttcatgt tatcagcaca ttatagaaat
    27721 ccagtaaact ttagtgatga gatgttaaat caagctaaag caggtcttga aagactatat
    27781 aatactaaag aaaaattaga atttacgcta agtaatttag tagaatctcc gttaacagaa
    27841 aaagaagtag agcttgttaa agaattagat gactttagac aaaaattcat agatgctatg
    27901 gatgatgatg ttaatacagc agacgcagta agtgtaatat ttgaattagc taagttaata
    27961 aattctaatg tagatgaaaa ttcttctttg gagtttgcta aaaaatgctt agatgaattt
    28021 aatgaactta caggagtatt aaatattgta aataagaaaa aggatactgt attagataaa
    28081 gacattgaag aattgataca aaaaagaact gatgcaaaga aaaataaaga gtttcaatta
    28141 gctgatgata ttagacaaca attactagat atgggaattg tattagaaga cacaagacaa
    28201 ggtgttaagt ggaaaaggat ataaaaatgg aaaaaactga attagttact atgtcaccat
    28261 tagttttagc atacttaggt gatacagtgt atgagacata tataagagaa tatttaatta
    28321 gacagaatac acaaagaaaa gttaatgatt tgcataaact agctataaag tatgtaaaag
    28381 ctaaagctca ggcaactata attcatgaaa ttgaaattga gttaactgaa gaagagagta
    28441 aaatttataa aaggggaaga aatcaaaagt caaatacttc tcctaagaat gcagatatta
    28501 tagactacaa acatgcaact gggtttgagg cattagtggg atatttgtat ttaaataatg
    28561 aaatagagag acttcaatat attatcaata aaggaatcaa aattattgaa agagatatgt
    28621 aaatattaaa gagtgttgtc ttaataataa gtaataaggc aacacttttt ttataactaa
    28681 tgtataataa atatatagaa attagtaatg agaaaggata aaaagttatg aaagtaaaat
    28741 taatatcaca tacacctgaa ccagaaaaag taatagctat ggcagctaag ctatgttatt
    28801 caccagttgg gacagacgaa atagaaaaag acttaacaga tgaaagtata gagaaatttt
    28861 taaatatgtt attaagtata ggtcatgggt caatattaga acatgcttca tttacatttt
    28921 caatagaagg tatttcaagg gcttgttcac atcaaattgt tagacatcgt atagctagtt
    28981 tttcacaaca aagtcaaaga tatgttaaat tagaacaatt tgagtacata attcctccag
    29041 aaatagaaaa aatagaaaaa gcaaaagagt tatttataga ctccatgaaa aaagaccaag
    29101 agaattatga taagttagtt gaaatattgt ttgaaaatca ttataatgac ctaataaaaa
    29161 acggtaaaaa tgagaaaaca gctaaaagac aagctgaaaa gaaagcaata gaagatgcta
    29221 gatacgtatt tccaaatgca tgtgaaacaa aaatggtatt tactataaat gctagaagtt
    29281 tgtttaattt ctttgaacat agatgctgtg aaagagcaca gtgggaaata agaaatttgg
    29341 ctgtggagat gttaaaagag gttaaaaagg ttgctcctat attatttaaa aaaactggtc
    29401 caagttgtgt aaatggaagt tgtccagaag gaactatgac ttgtggagat atagttcaag
    29461 ttagagaaaa atttaaggcc ttgtaggagg tgaataattt ggcgagtata gaaggaagaa
    29521 atccggtaat agaagcaata aaaagcgaca gagaaataga taaaatatta attgcaaatt
    29581 cagctaaaga aggttcaatt aagaaaataa taggaatggc taaagataag aatataatta
    29641 ttcagtatgt tgataaacat aagctagatg aagtaagtac aagtcattca catcaaggtg
    29701 taatagctta tgcaagtgag tataagtatt atgaattaga tgagctaata gatttagcaa
    29761 agaataaaga tgaagaccca tttttcatta tattagatga gataacagac ccacataatt
    29821 tgggttcaat aataaggaca gcagatgcag taggagcaca tggagttatc attccaaaaa
    29881 gaaggtctgt acacataact cctgtagttg ccaaagcatc tgctggagca gtagaatata
    29941 tgccagtttg caaggtaacc aatatagtta atacaataaa aagactcaaa gaagaagggc
    30001 tgtggattgc tgcagctgat atggatggag aaacttttta taaacaaaat cttactggtc
    30061 ctcttggtgt agtaattgga agtgaaggtt ttggaatatc tagattggtt aaacaaaact
    30121 gtgactttat agtaaaaatg ccaatgatag gtaatgttac atctttaaat gcatctgtag
    30181 caggtggaat acttttatat gagatattca gacaaagact ggataaaagt aaataggcat
    30241 gaaaaaaaat ataaatcatt acttaataat agatggctac aatattataa atgcgtggga
    30301 caatttgaaa gaactggcta aagaggactt agaagattct cgagaaaagc ttattgatga
    30361 cattatagaa ttttctgagt ttatgggtta taagactata atagtttttg atgcttataa
    30421 tgttaaaaat tctcgagaaa aagttgaaaa aagaaaacac ataacaatag tttatacaag
    30481 agaacaccaa acagcagata gttatataga gaaatttata acttctttat caaagtatga
    30541 tgatgtaaaa gtagccacta atgactatgc agaacagcaa atgattttag gaaaaggtgc
    30601 tactagaatg tctgcaagag aattaaagtt agagttagat cgttccaaga ataaaatgaa
    30661 ggaaaaaaat atcggtttga ggaaaaaaat tcagcgaaat tggttggagg aaaggttaga
    30721 taaagaaaca ttgtcgaaac ttgagaacat tcgtagaaag cgttgaaatt actaggttct
    30781 ttagactata atatacctat aaatttgttt tatatatggg ggagatttac atgttggtag
    30841 caaaagaaaa aagttatgag ttagtggaca attgtcagca ggatgagtat aacattgtat
    30901 taagagcaag tgaaggggat aaaatagcac tagagtacat tattactaaa tacagaaatt
    30961 ttgtaaaggc aaaagcaaag tcatattttt taattggagc agataaagaa gatataatac
    31021 aagaaggaat gataggcctt tataaggcag ttagagattt tgatggaagt aagaccaatt
    31081 catttaaatg ttttgcggag atatgtataa caagacaaat aataactgct ataaaaactg
    31141 caacaagaca aaaacatata cctttaaatt catatgtttc tttgaataaa ccaatatatg
    31201 atgaagagtc agacagaaca cttttagata ttatagctac aagtatagta acagatccag
    31261 aagagcttat aattagtaaa gaagagttaa aaaatataga atcaaaaatg aacgaattgt
    31321 taagtgactt ggaattagaa gtactagaat tatatttaaa tggaaagtca taccagttta
    31381 tagcggacaa gcttaaaaga gatgtaaagt caatagataa cgctttacaa agggttaaga
    31441 gaaaattaga aaaacatctt gaaaacagaa atgattaata gtaaaatact taccataagc
    31501 ttattgtgag caaaattaat ttatatcgaa agataaggga ggaaattcaa aatggctaaa
    31561 gctaaatacg aaagaacaaa acctcatgtt aatataggga caataggaca cgtagaccac
    31621 ggtaaaacta cattaacagc agcaataaca aaaacattat atgacagata tcaattagga
    31681 gaagcagtag atttcgcaaa catagataaa gctccagaag aaagagaaag aggaatcaca
    31741 atatcaacag cacacgttga gtatgaaaca ccaaatagac actatgcaca cgttgactgc
    31801 ccaggacatg ctgactacgt taagaacatg ataacaggag cagcacaaat ggacggagca
    31861 atattagttt gttcagcaac agatggacca atgccacaaa caagagagca tatactatta
    31921 tcaagacaag ttggagtacc atatatagta gtattcttaa acaaatgtga catggtagat
    31981 gatgaagagt tattagagtt agtagagatg gaagtaagag atttattaac agaatatgat
    32041 ttcccaggag atgacactcc aatagtaaga ggttcagcat taatggcatt agaagatcca
    32101 aagagtgagt ggggagataa gatagtagaa ttattcgagc aaatagatga gtatatacca
    32161 gctccagaga gagatacaga taaaccattc ttaatgccag tagaggatgt attctcaatc
    32221 acaggaagag gaacagttgc aacaggaaga gtggaaagag gagtactaaa agtacaagac
    32281 gaagtagaat tagtaggatt aacagaagca ccaagaaaag tagtagtaac aggagtagag
    32341 atgttcagaa aattattaga ccaagcacaa gcaggggata atataggagc attattaaga
    32401 ggagtacaaa gaaacgagat agaaagagga caagtactag caaagactgg atcagtaaag
    32461 gcacacacaa agtttacagc agaagt
//
LOCUS       DAEPUT010000043        30512 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.044, whole genome shotgun sequence.
ACCESSION   DAEPUT010000043 DAEPUT010000000
VERSION     DAEPUT010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30512
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.044"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            367..873
                     /locus_tag="KRL22_002164"
     CDS             367..873
                     /locus_tag="KRL22_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HBH1272653.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
     gene            1286..1954
                     /locus_tag="KRL22_002165"
     CDS             1286..1954
                     /locus_tag="KRL22_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272654.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQVGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            2113..2619
                     /locus_tag="KRL22_002166"
     CDS             2113..2619
                     /locus_tag="KRL22_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HBH1272655.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            2747..3763
                     /locus_tag="KRL22_002167"
     CDS             2747..3763
                     /locus_tag="KRL22_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH1272656.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            4117..4821
                     /locus_tag="KRL22_002168"
     CDS             4117..4821
                     /locus_tag="KRL22_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HBH1272657.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGGIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            5116..5595
                     /locus_tag="KRL22_002169"
     CDS             5116..5595
                     /locus_tag="KRL22_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH1272658.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVAGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
     gene            6227..6604
                     /locus_tag="KRL22_002170"
     CDS             6227..6604
                     /locus_tag="KRL22_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1272659.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            6597..7745
                     /locus_tag="KRL22_002171"
     CDS             6597..7745
                     /locus_tag="KRL22_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HBH1272660.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENAVRNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLVECSLKDKKEYALALIKSIKFSKNYNSKILTTEFDKTNLE
                     KRLESIVKKKGKSGILIAVLVFMTSITSFVEVDAQVRIDEGNNGMNNNINEFLLNKTT
                     DKIINIYYKDAPNEIRKFYEDKCELEGKIPRDYDIIEMDMKDYNQLIK"
     gene            7762..8364
                     /locus_tag="KRL22_002172"
     CDS             7762..8364
                     /locus_tag="KRL22_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBH1272661.1"
                     /translation="MLTKLRKIVAIMCCLLLTFTSVAFADTSKEKGGSKETVPEKNLD
                     SFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYA
                     SYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSF
                     GSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS"
     gene            complement(8457..9479)
                     /locus_tag="KRL22_002173"
     CDS             complement(8457..9479)
                     /locus_tag="KRL22_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH1272662.1"
                     /translation="MNYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNISKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNLKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(9808..9990)
                     /locus_tag="KRL22_002174"
     CDS             complement(9808..9990)
                     /locus_tag="KRL22_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272663.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFIIKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            10303..10722
                     /locus_tag="KRL22_002175"
     CDS             10303..10722
                     /locus_tag="KRL22_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HBH1272664.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            10853..12694
                     /locus_tag="KRL22_002176"
     CDS             10853..12694
                     /locus_tag="KRL22_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1272665.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDYYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            12721..14607
                     /locus_tag="KRL22_002177"
     CDS             12721..14607
                     /locus_tag="KRL22_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1272666.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDSDIISKIYIYLT
                     LSAISIRKYDKVNNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNGTRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            14615..16615
                     /locus_tag="KRL22_002178"
     CDS             14615..16615
                     /locus_tag="KRL22_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1272667.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            16877..18136
                     /locus_tag="KRL22_002179"
     CDS             16877..18136
                     /locus_tag="KRL22_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1272668.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            18197..19984
                     /gene="iorA"
                     /locus_tag="KRL22_002180"
     CDS             18197..19984
                     /gene="iorA"
                     /locus_tag="KRL22_002180"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HBH1272669.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            19986..20561
                     /locus_tag="KRL22_002181"
     CDS             19986..20561
                     /locus_tag="KRL22_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HBH1272670.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            20614..21684
                     /gene="buk"
                     /locus_tag="KRL22_002182"
     CDS             20614..21684
                     /gene="buk"
                     /locus_tag="KRL22_002182"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH1272671.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            21902..22603
                     /locus_tag="KRL22_002183"
     CDS             21902..22603
                     /locus_tag="KRL22_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272672.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            22663..23169
                     /locus_tag="KRL22_002184"
     CDS             22663..23169
                     /locus_tag="KRL22_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBH1272673.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            23344..24366
                     /locus_tag="KRL22_002185"
     CDS             23344..24366
                     /locus_tag="KRL22_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1272674.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIIQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(24513..24821)
                     /locus_tag="KRL22_002186"
     CDS             complement(24513..24821)
                     /locus_tag="KRL22_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH1272675.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(24881..25309)
                     /locus_tag="KRL22_002187"
     CDS             complement(24881..25309)
                     /locus_tag="KRL22_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272676.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(25536..26993)
                     /locus_tag="KRL22_002188"
     CDS             complement(25536..26993)
                     /locus_tag="KRL22_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH1272677.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            27411..28325
                     /gene="nadA"
                     /locus_tag="KRL22_002189"
     CDS             27411..28325
                     /gene="nadA"
                     /locus_tag="KRL22_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBH1272678.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKTLENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            28338..29639
                     /locus_tag="KRL22_002190"
     CDS             28338..29639
                     /locus_tag="KRL22_002190"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBH1272679.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            29620..30456
                     /gene="nadC"
                     /locus_tag="KRL22_002191"
     CDS             29620..30456
                     /gene="nadC"
                     /locus_tag="KRL22_002191"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBH1272680.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
BASE COUNT        12198 a         3105 c         5142 g        10067 t
ORIGIN      
        1 tataaataat agagtagaac ttgacaatta taacaatttt ttataaaact gaatcaagat
       61 aaaattaaat taatataaaa ataatataca ataaaaaaat gtagagagat acttactttc
      121 tacatttttt tattgtatat tgctttaggt ttaaaaatat attatatact ttataatcaa
      181 tatattttat ctatatttta cacttataaa atatgaaaac tacttattgc gaaagtaatt
      241 gatttgttgt attataattt acatgaatta tgtaggacaa tcaaaagtca gtattataag
      301 agtacatata ttcaaatttt taacaattaa tttatataat taaaaaatga agggtaggat
      361 gaagtcatgg gttttagaga agtaaaaatt gaggaattac agtttaatcc atttactaag
      421 attggcaaag aatggttact tataacagct ggtgattcag aaaagtttaa cacaatgact
      481 gctagctggg gtggtgttgg agtctattgg ggtaaaaatg ttgttacaac ttacataaga
      541 ccacagagat atacaaaaga atttgtagat agtaatgata catttacagt tgccttcttt
      601 gatgaaacgt atagagaggc tttaaatatt tgtggtacta tttctggtag agatataaat
      661 aaaatagaaa aagcaggact tacaccatat tttgtggatg atacagtagc ttttgaagaa
      721 gctaatatga ttatagtatg taaaaagcta tatcatggta atatgccacc agaaaacttt
      781 gatgctaaag aaaatgataa aaaatggtat ccagagaaag actaccatac tatgtacatt
      841 tcagaaatta taaaagttct tgtaaaagaa taattataat aaaaaatata tgaaaagaac
      901 ttattataag taaatgactg tgctttctta tctgatatct aagtagatgc tagtaactaa
      961 ataaatatta attttaaata aatactatta taaaaaagat gaactatatt tactatagtt
     1021 catcttttta tttatataag cacttatata agtagagatt tatttgaata aaagtattta
     1081 tttgaaatat ttgagtatac tttataagta tttttatgct aactagaaac acttaattta
     1141 tggcatttgt acttgattta ttttaatgta aataatttca aagttaattt tattcaatat
     1201 agtactataa aagtataaat aacatttaat aaaaatatat attatattag gtattttaaa
     1261 taaatttttt aaagggtgat tttttatgga aaatataact agttatttta caacaatact
     1321 atgtgtattt atatgcttat catctgtatt tatatttact caactagcta gagtatttat
     1381 taataagaag aagattaatc aaaaaattaa atcaagaaac ggatttaggt atgatagaga
     1441 ttttattgaa gccagaagag aagaaataca tataaaggat aacaataata ataaaaataa
     1501 gagtaacaat aagaaattaa aggaagaaaa agtatttaaa tacgataatg gtgatttata
     1561 taaaggtgag tttgttgatg gaaagaaaaa tggatttgga atatatattt tttcaagtaa
     1621 ggaaaagtat gaaggattat ggaaagatga caagatgcat ggaataggaa aatatactta
     1681 tagagatggt tcaatatata caggtgaatt taaatacgga ttaaaaaatg gtttgggaaa
     1741 attaacatat cccaataatg acatttataa gggatatttt ttagataata agaaaaatgg
     1801 taagggtgta ttatataaaa atgatggaaa taaacaagta ggaatatggg aagatgatga
     1861 acaatgtaaa agtttagatt ttaaagattt aaataataat aaaataaata atgtttatca
     1921 aaatagatta aataacaata aattaaaagt ttaattattc taataaaaaa atctttattt
     1981 atgatggaat ataggatata tctatgttgt aatttgtaaa atctttctat atcatataaa
     2041 attaagtatt gattagtcta ttacataaat atagaatata aatatatcca tttaataata
     2101 aggagaagag atatgaaaga gtatgtagtt gtggatttag aaactacagg attagatcca
     2161 tataaaggtt gtgaaataat agaaatagga ataacagaaa taaaaaatga acaaattgta
     2221 aaaaactatt caaggttgat aaaacctaag gggataattt cttcatttat aacagaattg
     2281 acacatataa gtaatgaaat ggtagaaaat gaagaaccac tagaattagt tttacctaga
     2341 tttagaaaat acataggtga tagaactata attgcacaca atgcgaaatt tgatttaaaa
     2401 tttttaaatt actatcttag aatgttagat ttagaaccaa taaacaatta tatatgtaca
     2461 gtagagttat taaaaaaatg taaaagttat aaaggaaaaa acaagaaact tgaaacagct
     2521 tgtgcttatt acaacataga gaatataaat gctcatagag ctgacagtga tacattagca
     2581 actgcaaaac tatttttgaa aataaaagat gaatattaat tataaatata gagaaaatta
     2641 gtgaaaatat cctttataaa attgaccctt aagcttacaa ttttgttctt tgatttattt
     2701 tgtagaacaa tgtataatgt accttatatg aagaagggag actaaaatgg gttattacaa
     2761 tgataatgat aataataaaa taagacgtaa aaaaattagt aacaacaaag atagtaataa
     2821 aaaatctaaa cattcttata cttcggcaaa taaaaaaaat aaaagtccta atacaagttc
     2881 cagtaaaaga atgagtgaaa aagtagattc acagaatctt ataaaaagag atagagatag
     2941 ttttacaaga gataatgtaa gacctttaaa tacagattac aatcaaagag aaagaagaag
     3001 agtcgagtat aaacaaagag agaaaaaatt aaaaagtaaa aaaagaaaaa aacaaaaaag
     3061 gattagaata gttagggcat tattatctat tatgttagtt gcactaatta tattttcagt
     3121 ggcaggtgca atatttacag tttcagctat aaaagggtca ccagaagtta ctaaaaagtt
     3181 aattaggtct aaatatataa gtagtgaggt tgtaagtata aaacaaatgc caaatgattt
     3241 aaaacatgca atagtttcca tagaagatga gagattttat aagcataaag gagtagatgt
     3301 tatttctcta gttaggtcag tattaaacaa tgtgtttaca gatacaacac aaggtgcaag
     3361 tactatagat atgcaagttt caaaaaacct gcttactagt aatgataaaa ctatgaagcg
     3421 gaaaataagg gatatgtata atgctaagca gatgaataag attatgacta aggatgaaat
     3481 tcttgaagca tatttaaata atatgtatct aggtaaaaat gcatatggag ctgcaaaggg
     3541 agctgaagtc tacttcggta aaaaagttag tgaattaaat ttagctgagt gtgctatgtt
     3601 agctggtatg acaaataatc ctgcaaggta tattgaccat ggagaggcta agaagagaca
     3661 agtgattgta ctgtataaga tgcatcagct tggttatata actgataagg agtatagaat
     3721 agcaaaagct gatgacactc catttaaatc agaaattgat taaaattgta agaatatagt
     3781 attttcaata gtttaaacaa acgaaaatgt aataaaaaag gtgatttgcc acccgtttgc
     3841 caccataatt ataatttaat agcaaattgt tttaatgtac aaatcagata atataatatt
     3901 gttttaaata ctacattatg ctaaaattta attgtatttt gtaaattaaa aaacttataa
     3961 tttagttttc tagggttccg cattttataa tggtcaggtc caagagaaaa cgcacaattg
     4021 ttgtgtacac ggaaggataa aagcctggga gatatttaat aatatttcta taggcttttt
     4081 tatttttaca tattttaaat ttgaggaggt tttctaatga aaaaatttgt tattgaggat
     4141 gcattttgga atctatttcc tagtgcaaaa attggagttg ttatttgtaa tgatatagat
     4201 aactctataa aagatgaaga ctataagaaa ataattttga agggagaaga agaagcatta
     4261 aaatacttgg aggactcaga atttagcaac aaccaagtga ttaaagtatg gagagaagca
     4321 tttaaaaaat ttaaaacgaa aaaaggagca aggtcttcta ttgaagcatt attaaaaaga
     4381 gttcataatg gaaataatat aggaactatt aaccctttag tggatatcta caattttatc
     4441 tcattaaaat atgcattacc ttgtggaggg gaggatatag ataaatttat aggaggtatt
     4501 aggctaacta gagcaattgg taatgaggag tttatcccac tagggacaga tgaaaattca
     4561 tttccatatg aaggagaaat aatttataaa gatgatggtg gagcaatttg tagatgttgg
     4621 aattggcgtg aagcagtgag aacaatgctt actgaagata ctaacaatgc ctttttatgc
     4681 attgaattag tagatgaaag tagatttaaa gaatttgaaa atgctttaaa tgaattagct
     4741 aaaatagttc aagaaaaatt gggtgggaat tgtaaaattt caattttaga tattgataat
     4801 aaagaggtat cagtggatta atatggaggt gctgttgtaa tggactattc tagttataaa
     4861 gatacttata tttagggtaa gaaggtctat tttagatata acgattatca aaggatataa
     4921 tatagaaaat aaaaatgtag aatataaaaa gcctttaaaa taagaaaaaa atgtatttta
     4981 aaggctttta ttatactctt ttttatttgc ataattaaca ataaaaatat attgttaatt
     5041 ataatatttt tattgaaaaa cgatataata taatgtatta tactatatat aaaatatttt
     5101 aaaggagttg gcatgatgtc taataaactt ataaaaaatt tactaagtgg tatattacaa
     5161 attttatttt ttcttttagg attagtaatt gttgcaggag gatttaaaag ttttatgtac
     5221 ctctgtttta gtggagaagc aactctacaa ggtactattt atggaatatt aatgtttatt
     5281 ttaggtgtat catattttat cattataaaa tcattgatag aagtattagg tagttctgaa
     5341 tatagcctat ttgtaaaaga gaatgtaaaa agatttagga ttattggata tcttttgctt
     5401 ttaaactctc taattgagtt tatttcaact tttggtacta ctggaaaagg aatgagattt
     5461 ctagatttag gatttggatt ttattttact gttccagtat ttgtatattt tataacttct
     5521 ctgatgagtt ttgtaattgc agatggattt gtaaaggcaa taaagataaa agaggataat
     5581 gatttaacta tttaggtgtg acactttaat atataggaga taaataaccc gaaaagagtg
     5641 attaactagt aatttaaaat atattagggt ataatacata aactataatg ctaaaattaa
     5701 aagattataa tactaaaata taattatgtt ttaattaaaa taaagaactt tattagtaga
     5761 tattaaaagc acatttttta taaaagtgct tttttataat ttatgaaagg tataattata
     5821 aaagtcttat tcaataaaat ttataattaa tttagatgta tttgtaaata atcagtataa
     5881 aatagatgtt ttaatagcat aaaggcataa ttagaaggtt attaaaattt attagatatt
     5941 actctagttt attttaaaaa aaagtattat aatattcctt gtgtgaaaat ataggaattt
     6001 ttattaaaca gttttaatgt gtaaataaca ttctacacta ttgtaattaa atatgtaaaa
     6061 agtaaaatat ttaaatagat atattttaaa atctaacttt taatattgta aaaaaattag
     6121 aaatttaaca aaaagtacaa aaattcacat ttttttcata aagtgtttga ctaaaaaatt
     6181 cacatgttgt agaattaagg tagcaggagt tttgagggag gtgtaaataa tgataagaaa
     6241 aataccacaa gcagaactaa aagtaatgaa attcatttgg aaagtagatg ttacagtgac
     6301 atcaaaagat gttattgaag ctatggaaca aaaatatggc tggaaacaaa ccaccacact
     6361 gacactttta tctaggctgg taaaaagagg attcttagat gctcaaaaaa tagacagata
     6421 tacacattac acaataagag taaaacacaa agattattta agttttgaga caaaggattt
     6481 cctaagtaat atacatgatg actctttaag aagcttaatt tcagcattac atgatgatga
     6541 aaatataggt aaagataagc tagattttct agaaagttat tttgataatt taaaggatga
     6601 ataattatat gctatatgtt tttgaaaatc ttataaagac aactattgta tgtagtcttg
     6661 gtatttgtct attattattt ttgaaaagat atttatttaa gaagtttagt aagagattca
     6721 attattatat ttggttgata atagtcttta gaatgttact ttttctattt aattatacaa
     6781 tagtatatga agtaaaagaa cccaaagaaa atgcagtaag aaataatatt acacaaattg
     6841 atatttctac agataataat cttatgctgt atgtagctta tttatggtta tttgtaacta
     6901 tagtcattgc agtttataca tttataaagt atacaagatt taaaaatcta gttgttgatg
     6961 tatcttatga tattgaagat aatgatataa actgtatcta caaaaacttg ttaaaagaat
     7021 taaatataaa aaagaaaatt gaattaagag gttctgatga attgataagt ccagcaggta
     7081 tgggattatt taaatcttac atattcttac cagactatcc ttatagtaaa gatgaactaa
     7141 cttggatttt gaaacatgaa ttaatgcatt ttaaaaataa agatatttta ataaagtttt
     7201 tagttttgtc tgttagaata atatattggt ttaatccact tgtatatgta atgagcaata
     7261 aagtaaatct agattgtgaa ttatgttgtg atgaaagtgt tttggtagaa tgttctttaa
     7321 aagataaaaa agaatatgca ctagcactta taaagtcaat taagtttagt aaaaattata
     7381 atagtaagat tttgacaacc gagtttgata agacaaattt ggaaaagaga cttgagagta
     7441 ttgttaaaaa gaaaggcaaa agtggaatac taattgctgt tttagtattt atgacttcta
     7501 taacatcttt tgttgaagtt gatgctcaag ttagaattga tgagggtaat aatggaatga
     7561 ataacaatat taatgaattt ttattgaata agacgactga taaaattata aatatttatt
     7621 ataaagatgc accaaatgaa attaggaaat tttatgaaga taaatgcgaa ttagaaggta
     7681 aaatacctag agactatgac ataatagaaa tggatatgaa agattataat caattaataa
     7741 aataattata aggaggattt tatgttaaca aaattaagaa aaatagtagc tattatgtgt
     7801 tgcttattgc ttacttttac aagtgtggca tttgctgaca caagtaaaga gaaaggagga
     7861 agtaaagaga ctgttccaga gaaaaaccta gattctttta ctctttctgg gtatatatat
     7921 acatatgaaa atgcgccaca agaaataaga gatgaacata aacaaaattg tgaagagata
     7981 aatatagacc ctaagccaga tgatgagata tttgttccag aatcagctaa tctaatgaat
     8041 gaggacaata gtaaaggtgt ttatgcaagt tatactgttt cttataatat aggtgctaaa
     8101 actataacaa ttatgagtaa tgagtatttg actataagta caacaaaagt tatacgaaag
     8161 ggtaatagcg gaaaagaagt aaaagctgca caaatcatgt taactttact tggttataat
     8221 gtaggtatag atagttcttt tggaagtaag acatataatg cagttgtaag tttccaaaaa
     8281 aaatacggtt tgtctgcaga tggaataatt ggtccagcta cttgggataa attgggtaga
     8341 ctaactgacc ctactctttc ataggattaa aatctaaaaa tatattaaat agtgtctcaa
     8401 tatgattttt caatttaaat gagacactat ttaaatataa atgttataaa actattttac
     8461 aataaattcc atataactct accatctata tccttaacat tttgacaacc agtcaaaatc
     8521 atagtctcac ataactcatt cctaaccttc tctataaaaa actccacacc atcaagacca
     8581 ccgccaaaag aagcagtaac aaaaggtctt cccatcaaaa cagcatcagc acccaatcca
     8641 agcatcttaa ctacatcaac accagtccta actccaccat caacaagtat tgttatcttt
     8701 ccctttacag acttagctat atctggaagt acctcacaag taccaggagt ataatcaagt
     8761 actcttccac catgatttga aacaataatg gcactagcac cagactctac agccatcaaa
     8821 gcatcatcta cagtcataat tccttttata ataaaaggta atctagtgga ttcaaccaat
     8881 tctctaatct catcaattgt tttaggagaa aaaggatttt cttgaaattg attattaata
     8941 agtccacaag catcaaggtc tacaccaact gcaaaagcac ctgcttcttc agacaatcta
     9001 attttttcta ttatctttaa attattccaa ggctttataa atacaattcc atttcctcta
     9061 ttatccttca acacatctaa attatccagt aaaaaagtat ctacattagt atcgccaacc
     9121 atagcataaa ttccagaatt agaacaacct ctaacaacag gctctatgta ttctttttcg
     9181 gaaactttac cacccatgtt caatatagta cctgatacag gtgcagcgaa tataggagaa
     9241 ctcatttttc taccaaataa ttctatggat gtatctggct ttgaaatatt atgtatgact
     9301 ctcatattta tctttatttt ttctagactt tttctatttt caatgaaaga cgaaccactt
     9361 cctttaccac ccataccagg aacatctcca gcacaagcta atccattaca aattttacat
     9421 actttacatg ttccattaaa gttctctcta gctgatttta gtaagtcatt gtaattcata
     9481 caaaatctct cctttttata atattaaaat tgagtattac tatattgaaa atatcttaat
     9541 tgtaaatata gggatgttat tatgatgagc taaactagat aatacatatt agatattttt
     9601 tattgttgta gatagttaaa ttatatcata ttagatagtc aaattttgaa aaaaactaac
     9661 ttatttaagt atacattttg aaaaaattaa aaaagctata tatagatttt taaagaaatc
     9721 tatatatagc ttttaagttt atgtcaatct tttttattaa tgaataaata atatagaata
     9781 caatatacaa aaaagtttct tgaaatgcta agataatccc catttacaaa gcaacatcat
     9841 tatactgtgt aaatttgaat caacaatgtt ttcaccatat tttataataa aatcctctaa
     9901 ttgtgtgtca ataaatgaat aatatccact tatactatcg atgtatgcag tcattaagtg
     9961 tatacattca tcacttttat ctttatacat atatatctcc ccctatatac aatatataaa
    10021 tttagatacc aaattgtatc atattaaata gttaagtgtg taacatctat gcagttatat
    10081 atttatatca ttatattaat aactaaagtg agttttgaca atagattttg ggaaactgga
    10141 tgttcaaagt gcaaacttgg attttaaaat cattaattaa aatagtgtat atgaatatat
    10201 gtatacataa cttaattata aagattataa acaattactt ttattaactt tatttaaatg
    10261 gtagaataac ttggagatta ataattataa ggaggatata atatgagttt atataagttt
    10321 atatatgatg ataaggaata tttattaaaa gaggagaact gtagtgcttt aataaatgat
    10381 gaagaaaatc cagttcaagg agtaagtatt tcaaaaataa ttgatatact taatgaagca
    10441 gaagaagttg attttgatgt agaatattat caagaagcat gtccattatg tttagaagga
    10501 gtaaaagaaa agaaaaaatt ctttcctttt ttagaatatc acttttatat tttcagtaaa
    10561 gatggagaat atgtaataag caatatatct gttgattata aaggactatc ttttaataaa
    10621 ctatcaaggg caaataaagt tgataatagt tatattgtaa gtgtgataat ttgcgaaaat
    10681 tgtcaggatt atatagttca gatagaaaat tgtatagttt agtgtaaagt atgtcttaat
    10741 ttaagagaaa tttctaaatt gagacatcaa cttttttcaa aaatagtatg gaaaattact
    10801 aaatttatga gataatgtaa gtcggaggtg agttacaata tatagtaaat atttggaaga
    10861 gatagatgat acaattttag attcaatgtt taaactaacc ttgaatgaaa gattattgac
    10921 taataacgat tttattgaaa ataaaattga tgtagtaaag aatttaattg attactataa
    10981 aactgaacaa aatagtttaa tgttattaaa atcaaatttt ttgctagctt tattatatgg
    11041 tattcaaggg tttagtgaaa aaatgaaaga gtatattttg atttcctgta aatatattga
    11101 taaatgctta cccaaagatt ataaattttt agcacgattt tattcacaaa tagctatttt
    11161 aagtttaaaa aatgaagatg taaataaggc aaatttatat atggataaat ttaatcttat
    11221 ttgtgatgaa aataattttc taattgaaga aattattttt aaatcacaac ttatttacat
    11281 taaggcaagt aagtgtatag aatcttctgt aataattaaa gaaatagaaa cgttgtatat
    11341 aaagataaaa gaaattaacg attttaattg taaaaaaata tattttttta ttattggtaa
    11401 aatatatttt ttgtttttgg atgatgctct aattgctaag gtaaattttt taaaagcaag
    11461 aaaatatgca gatttactaa aggatatgca agtatcttca ctatgtaata taaagatagg
    11521 tgagtgtgaa tgttcgtttg aaaattatga atgttccatg gaatatttca atgaagtaat
    11581 aagcaataaa aagtatagaa atgtaaatat aattcaaaaa tatagagcat caaacaacat
    11641 aactaaaata ttaataaaga ctagaaatta tcctgtcgca ataaataatt tagcaaaatc
    11701 tgaagtatat ctagaaaaaa ttaaaaatca tagcttaaaa gaagtagaga agtttgattt
    11761 atttataagt ttagccatgt attatgcaaa aagtaatgaa aaatcttttg aacaatcaat
    11821 atgctattta gatagagcta aaaacatatt aaatatgata aaaaatatag aagaatatat
    11881 aatatatgat ttagaaataa tttatcacca ggcaaagata tattatatct ttggatatta
    11941 tgacaatgcc ttaaacacaa ataaaaaact ccttgaaaaa tctaaaaatg ctaaaaatta
    12001 taattatgtg aagttagcat acaagagtat atatttgtgt tttgaaaaga ttcaaaatta
    12061 tgaaatgagt atgaaatact ttaaaatgta ttatgagtta aaaatgatgt atataaaagc
    12121 tcgaaataga aattatatag attccttaaa ttatagacat gagtatatag aaaaagaaat
    12181 aaataacatg agaaaagtaa aacttgattt agataaaaaa aagtatgttg accatttgac
    12241 aagtgcatat aatagaactt ttttgaacga ttttttagaa aaacaagaag ttagtgaata
    12301 ttgcacagca tttatgatag atgtagatta ctttaaagaa tacaatgata cttatggaca
    12361 ctataatgga gatattgctc ttaaaaatat aactataata ataaaaaaat atctaaaaaa
    12421 agacatgctt atgataaggt atggtggaga agaatttctg atattatctg tatgtaaaga
    12481 ttataaaaaa agtaaaatat ttggaagaaa attatgtagg attgtaaaga aatttttaaa
    12541 caataatttg acagttagta ttggcattga tacatgtaaa aatagtagta tagatataaa
    12601 agaaataatt gaaaatgctg ataaagcttt atataaagca aaggaaagtg gtagaaatag
    12661 atgtttgcat tatcatgatt ttaagaattt ttaactgttg aaataggatt ggtgatttac
    12721 ttgaaaagga gtttaataga agatttaaag agaaatataa acaagataga atacgatatg
    12781 ttgactaaat tctatctaaa tttgacagat ttaaactaca tcttggatta tcacaaagac
    12841 cttttaaata caaaattaga agataatagt agagtctata ctttatattt aattagtctt
    12901 ataaactata taaaaaaaga tagagaagca tcatacaact acttgataga gtcattaaag
    12961 tatattaaaa aattgtcatt aaaagatgat tcagatataa tatctaaaat ttatatttat
    13021 cttactttat cagctatttc tataagaaaa tatgataagg taaataattt ttatttctcc
    13081 gcaaaaaaaa ttataagaca aaatcattta aatgagttgt tggtattgtt aaatatgagt
    13141 ttatgtgtgg aaataagtgc tttatatcag accaaaacgg atgtaatagc tttagtagaa
    13201 gaagtgtctt tttttaaaac tttaaaaaat aaagctcttg taagtagggc aaattatata
    13261 tttgggagag tttatctata tttatttaat aactttataa aaagtatgga atacttaatt
    13321 gaatgtctaa aattggctca agaaaataat ttatactcta tagaggcttt ttgtaaatgt
    13381 ataataagtt tgtgttattt agagagtgga aataatgtag aagctataaa atacataaat
    13441 aatgtattag atgttgcaca cagtaataac tcaatatcag taactgaaag agtgtctata
    13501 aaaatagacc ttatatgggc atatttaaaa gaagatatga ataaagaagc agaagttatt
    13561 ttattaaaga ctataaaatt aatgaaagtt gttgaaggtg tatataagga ttatttatat
    13621 tcatttatat ttttatattc agctgaaatt gagttaaaga aagataattg tagttttgaa
    13681 aaggtaaaca cctatttaat tttatcaaaa aatatatata aaagttttgg agatgttttt
    13741 atatataatt ctaaactaga ttacatatat aagttgtatg gagatttata tataaaattt
    13801 ggtaatatag atgaaggtat aagttgttat ataaaaggtt taaatttagt taaaaagagt
    13861 tcattgaatc ttagaaaaat atctatattt tatgggctaa tagcaaatgg atatgagcta
    13921 aaaaaagatt ttaaactggc aatagaatat tataaaagta tggattggta ttctgatagg
    13981 tgggaaaaaa ataattccta taaaacatct caagcaattc acaaacaata tgaactcaga
    14041 caaaaacaag agagtttaag gttactagtg gatgataata agaaattaga aaatgatatt
    14101 ttaaaagatg gacttactaa actatataat agaagatatc tggaacagca gttggattta
    14161 tttaatggaa ccagagacaa aaatatggtc gcaatactgg tcgatataga ttgttttaaa
    14221 agttataatg ataattatgg tcatctagca ggagataaag ttatagttaa ggtaactgat
    14281 attataagaa gtgtatttat agatattacc gaacacataa tcagatatgg gggagaagaa
    14341 attttaatat tagtagattc tatagaatca atcggtgttg aagagattga taatatagaa
    14401 ttatatatta aaagagtttt caaacttctt gaatttgagg gtattgaaca tatatattct
    14461 aaaataaaaa actatataac tataagtgct ggagtaagta taaaaaggtg tcgtagtaga
    14521 aaagatgttg aaatattaat tgaagatgca gataagaacc tatataaatc aaaaaaagca
    14581 ggtagaaatc aatacattat aatttaaaat tgaggtgatt ttgttgcgaa aaaaaatagg
    14641 aattatagcc tctgatattg aattaaaaga aagaatagaa gaattatata gagaagatgt
    14701 agaaaatgga actataataa tcgacatact taacctagac ttaatggaaa atcaaggtcg
    14761 tatacttgtt gaaaaaggtg cccaagctat aattggtaga ggtggaggtt atagcttagt
    14821 aatagataca gtaaatgtac ctgttatacc aatgaatatg aagtcaactg accttttaag
    14881 agcaatagaa atagcaaaga aatattctaa aaaagtagta ttgattcttg gagacaatga
    14941 agtttctttt gactatgttg gctggagaaa tgtcataagt actgaaataa ctgaagaatg
    15001 gtttgaatct aagtatgaga taagaagtaa agttgtaaaa tatatagacc aaaaagatga
    15061 agttgtaatc gtaggaggag gtttggcatg ttcttttgca aggcaatatg gaattgatag
    15121 tgtatttgca actgctagtg atgaatctat aagagaagct gtagaatatt gtaaaaaatt
    15181 attagataca ttaggtgaag aaaagtttaa taatgaagtg ttacgaaata tacttgatgg
    15241 tataaaagat ggagtaattg ctatagatag taatggcagt ataattttgt acaatgaaag
    15301 tgcaaaaaac atgcttaaag tagagagaaa atgtgcactt aataaataca tcttagatgt
    15361 atttcctaaa atggagtgga tgttagattg tttacatgaa aaagaggacg tagaagatag
    15421 aaagataaga aatataaata atctaattgt taatactagg acaacattga taaaagttga
    15481 taatagtact tatggagttt taggaataat acaagatata accaagctac aaaacttaga
    15541 aagaaaaata agatttgact tgaatcaaaa aggtctctat gctagatata cttttgatga
    15601 ttttttattt aaagataaat taactaaaga atttattgaa gaagctaaaa aaattggaaa
    15661 aagtgattat acaactttac tttatggaga aagtgggtct ggtaaagaaa ttatagctca
    15721 tagtatacac aatataagta aaagaaaaga taggcctttt gttgctataa attgtgctac
    15781 tatagcagaa aatttacttg aaagtgaact ttttggctat gaagaaggtg catttactgg
    15841 tgctagaaag ggtggaaaaa gagggctatt tgaacttgct catggaggga ctcttttttt
    15901 agatgaaata aatagtctat cctttaatat tcagacaaaa ctattaagag taatagagga
    15961 acgtcaaata atgagaattg gttctgatta tataatacct ctggatataa ggattatagc
    16021 agcaacgaac gaatctttaa ccgaaaaaat agttatgggt acatttagag cagacttatt
    16081 ttatagattg agtagtttag agataaatat acctccttta agagacagaa gagaagatat
    16141 aatacctttg tttaacaatt ttgtaaatga agtattaaag gatgatggtc tcaatggaat
    16201 aaacagtata gatgaaaatt ttgttttgac taaagatgaa atggataagc tatataatta
    16261 tagctggcct ggaaatgtaa gagagttaaa gacaatagct caaaaatatg ttgtgacagg
    16321 taaaattaaa ttgagacaag atagagattt taaaactaaa aaattacttc ctaactctga
    16381 agtagacaaa tttaattctg aaacgacagc aagtgtagaa gtccaagatg aatctataaa
    16441 tataagtaag ataaatgatg gtaagataag tatagatata aaagaagtaa ataagtatgt
    16501 tgaagaaaaa ataataagta tgctttttgc tcagggactt tctaaaaatg aagttgcaca
    16561 agttcttgga ataagcagga catctttatg gaagaaatac aataaaaata tttaaatata
    16621 attacatata aattattttg aagtaatgtt aattttttaa aacaagtgtt aagaaaaatt
    16681 aacattactt ttttgcaaat ttttattttt ttagacaggc atatatattt ataagaaaaa
    16741 tagttaaaac acttaattta ataatgaaaa aaataataat tctaaacaaa atcaatttta
    16801 cataaagtgg gatttattgg catagtaatt gcttaatata taatgtaaga gtaaatacaa
    16861 ttttaggggt gatggtatga gtcaaagtat ggttggtaag catgcaatgt ggccaaaaga
    16921 aaatgatgtt atatttagca tatctggcag agctcaagca gcagagaagg cttttggtat
    16981 ggataatgta ataaatgcaa caataggcgc tctaatggat gattcaggaa aattgataac
    17041 aatgaaaact gtatatgaag aatataaagc attagataac tgtgagatag gtgcatatgc
    17101 agctcttgaa ggtcaaccag attacttaga agcagttaaa aaagtatttt tcagagatta
    17161 cttaccagaa ggacatataa gagtattagc ttcaccagga ggaagtggtg caataaaatt
    17221 agctgtatgg aactatacta atgaaggaga tgaggtatta acatctgatt ggttctggag
    17281 tccatatgta agtatagctg aagaggctaa tagaaaagta gttaattacc aactttttga
    17341 tgaaaataga aggtttaatt ttgagtcgtt taaagaaaaa tttgtaaata tagcagaaaa
    17401 acaaggtaga gtctttacaa ttataaacac accagcgcat aatccaactg gatatagtgt
    17461 tgcagatgat gagtgggata aaatattaga cttatcaaaa gaagtcgcaa aagataaaga
    17521 caaaaagata atatttttcg tagattcagc atatattgac tttgcaggtg atgatgatgt
    17581 atgtagaaag ttttttaaga aattttctaa tttgcctgaa aacgttctcg tattggttgg
    17641 attcagtatg tcaaaaggat ttacagctta tggtatgaga atgggggcta taatttgtat
    17701 atcttcaagt gaagatgtag ctgaagagtt ccattactca tgtgttcatt catgtagagc
    17761 aaattggtca aattgcaata gaagtgccat ggcagtatta tctaacattg taaatgaccc
    17821 taaaaaattc aaagaatatg aggatgaaaa agaaatatac aaaaacatgc ttactagaag
    17881 agcagatgta tttgtaaaag aagctgaaag agtaggatta gaaattcttc catatatagc
    17941 aggtttcttt gtaagtatac catgtgataa tccaaaagaa gtatgtgaag aattgactaa
    18001 acataattta tttgcagttc cattaaaaat gggcttaaga tttgcagttt gtgcagtttc
    18061 tgaagataaa tgtaagaaag caccaagtat tataaaagaa gcacttgaaa gtttagaagt
    18121 aaaaataaat aattaatttc attgaacaaa ttgggtggac tatgaattta ataattgtag
    18181 atggagggaa ttttatatga aacaattgat gacaggtaat gaagcaattg cacgtggagc
    18241 ctatgaggct ggtgttaaat atgcatctgc atatccaggg actccaagta cagaaatatt
    18301 agaaaatata gcaacatata aagatgcaat agttgcagag tgggctccaa acgaaaaggt
    18361 agcacttgag gctgctatag ggggttcaat tgcaggagca agaacaatgg cttctatgaa
    18421 acatgttggt ttgaatgttg cagctgatcc aatatttact tatgcatata ctggggtaaa
    18481 tggtggtatg gtacttatta cagcagatga gccgggaatg cattcatctc aaaatgagca
    18541 agacaatagg atgtatgcaa aatttgcaaa gataccttta tttgaaccat caactagtca
    18601 agaagctaaa gatatgataa aagaagcttt tgaagttagt gaaaaatacg atacaccagt
    18661 tttatataga gttacaacaa gactttgtca ttcaaaagga ttagtggagt gctatgatag
    18721 agaagaagtt gaaattaaag agtatgttaa aaatgctaag aaaatggtaa ctgttccagc
    18781 aaatgctcaa ataagaaggg gcgttgttga agaaagaatg gaaatcctta aaaaattctc
    18841 aaatgaaact gatttaaact actatgaaat aaatgataca aaaataggtg ttatagcctc
    18901 tggtatgtgt tgtaattttg ccaaagaagt ttttggaaaa aatgcatcat atatgaaact
    18961 aggatttaca aatccattac cttatgaaaa aataaaagaa tttgcagaaa aagttgataa
    19021 aatatatgtt atagaagaaa atgacccatt tatagaagaa caaataaaag catatggaat
    19081 agattgtatt ggaaaagatg taataccacc atatggagaa atgacaccag atgttttaag
    19141 aaaagctata tttggaaaaa caaatgatac tatagaatac aaatctgaat tagtaacacc
    19201 aagaccacca agtttctgtg caggatgtcc acatagagga ttcttctatg aacttggaaa
    19261 gagaaaaaat ttaatagttg gtggagatat aggttgttat actcttggat ttgctcctcc
    19321 atataatgga atagactatg ttgtttgtat gggttctgct tttggaactg cacatggagc
    19381 tcaaaaagtt cttaatatga aggatgataa tgaaaaaaga ttggtaggtg tacttggaga
    19441 ctcaacattc ttccatacag gaataaatgg acttttagat gttgtttaca atagaggtaa
    19501 ttctatttcg gttatattag ataatagaat aactggaatg acaggtcacc aagaaaaccc
    19561 aggttcagga tatactttac aaggtgctaa aactaaagaa gttgatatag aaggattagt
    19621 taaagcttgt ggaatagaac atgtaagagt tataaaccct aataatttaa aagaagtaaa
    19681 tgaagcacta gattgggctt tagctataga agatgaacca tcagtaataa taacaagatg
    19741 gccatgtgta cttaaaaaat tctctaaaga agatatagaa gaatttaata atccatttaa
    19801 gactaagtgt aaagttgacc atgataaatg tataggatgt aaattatgtt tgaaaactgg
    19861 atgtccagct ctatcatttg ataaagagaa taagttatca aatatagata gaaatcagtg
    19921 tgtaggatgt ggagtatgtg cacaagtttg tccaaaacaa gcaatagtta aggaggaaaa
    19981 ataatatgac taagagtata cttttggtag gtgtaggagg tcaaggaact atacttgcta
    20041 gtaaattatt aactatggga ttgatggaag ctggatatga tgtaaagatg agtgaaatac
    20101 atggaatgag tcaaagagga ggttcagttt cctcacaagt tagatatgga gattgtgttc
    20161 attctccagt tatagaaatt ggtggagcag atatattagt atcttttgaa aaaatggaag
    20221 ctttaagatg gttcaattat ttaaaaccag aaggaaaagc tttagtaaat aatcatagga
    20281 tagattctat gactgtttta atcggaggag ctgaatatca agaaagtgat atagatgcag
    20341 agttaagtag attaaatgca aaagttataa atgcagctga taaagctgaa gaactaggaa
    20401 attcaaaaat aatgaatgtt attttattag gatgtctagt taaatctatg caattagagt
    20461 ctattgattg ggaaaaaatt ataagtgaaa atgttaaacc aaaatttgtt gaattaaaca
    20521 taaaagcttt ccatgaaggt atggaaatgg ttagcaaata gtttataata gatataaata
    20581 gactatagaa attaaggtga aaggaagaaa attatgactt acagaatatt agccataaat
    20641 ccaggttcta cttctacaaa aatagcagta tatgatggag aagaacaaat tcttgtgaag
    20701 acgatagacc atccggctga agagattgca aaatataata ctatacaaga ccagtttgaa
    20761 atgcgtaagg aagcagtttt gaatattctt aaagaaaata gtatagactt aaaatctctt
    20821 agtgcaatag taggaagagg tggagtttta ccaccagtaa aatcaggagc atatttagta
    20881 aatgaagaaa tgattgatgt actaagacat agaccagtac ttgaacacgc ttccaattta
    20941 ggtgctgttg tggcacatgc aatatcagaa cctcttggaa tcaactcata tatttatgat
    21001 tctgttgcag tagatgagct tatagatgta gcgagaatat ctggactttg tggaatggat
    21061 agatcaagtg cagggcatgc attaaatact agagcaatgg ctttaaaata tgctaaggat
    21121 aaaggaaaag attataagag cttaaactta atagtagctc atattggtgg aggagtaagt
    21181 atttatcttc atgaaaaagg aagaatggtt gatatgctat ctgatgatga aggaccattt
    21241 tctccagaaa ggtcaggaag agtacctgct acaaaattag tggctgcctg ttattcaggt
    21301 caatattcag aaagagaaat gactaaaaag ataagaggta aaggtggtat agtttcatac
    21361 ctaaatactg tagatgctag agaagttgaa aaaatgatag cagaaggaaa tgaagaagca
    21421 aaaattattt atgaagcaat ggcttatcag ttagcaaaag gtattggaga gttagcaact
    21481 gtagtagatg gaaaggtaga tgctataatt ataacaggtg gaattgcata ttctgaaatg
    21541 tttacttcaa tggttaaaaa gaaagttgag tttatagcac cagtagaaat tatggcagga
    21601 gaaaatgagt tggaatcact tgcttttgga actttaagag tactaaatgg agaagaagaa
    21661 gctagaatct atagtgaaaa ttaataagaa aaactaaaaa tgtttatata ctaaaaaagt
    21721 ggtatatccg ttttttatac acgaaagctt agagtatagg tgaaaatgta taaaatttgg
    21781 attgccactt tttataatta aaattttatc ttaacctaat aaataattct gtaaaatttc
    21841 gtatttatat atatatttta ttggtattta ttgttattat tattatgagg agtgattttt
    21901 gatgggaaaa ataagtttaa aaagtatgat aagattattt tcaggttttt ttatatttgc
    21961 aatttcttct gtgcttatga ttaatgcaca tgtaggtctt atgccttggg atgtacttca
    22021 ccaaggttta tctataaagc taggcataac tataggtcag gcttctataa tggtaggagt
    22081 tgtaattgtt atattggatg cagtttttgg tgaaaatata ggatggggta ctttactcaa
    22141 catgacattt ataggaattt ttattgattt agtaatattt tctggagtga tacctcatgc
    22201 aagcaacact tatataggtg tgtttatggt tgttatagga attattttgg cagctatagc
    22261 aagttttcta tacttaggtg tttgtttagg aagtggaccg agagatgggc ttatgattgc
    22321 tcttcagaaa aaaactaata aatctgtacg tcttgttaga acaattcttg aaatactagc
    22381 attagttgtt gggtggttat taggaggttc tgtaggtatt ggtacgcttg taagtgcttt
    22441 aggtttagga tatgtattac aaatagtgtt tagaatattt aaatttgaca caaaattgct
    22501 gaaacataga tttattatag atgatataag agaatggaag gaaaagaaaa gcaatgaaca
    22561 taaatgtaaa tcaagtattg taataaaaaa tgagcagaat taattatgct aaaatatatt
    22621 tgtagtttat ctaatttata gtaaagtcaa ggagattttg aaatggaatt atgggattta
    22681 tataatgctg atggaattaa aacaggaaat gttataaaaa gaggtaattc tattgaagaa
    22741 ggttattacc atttggcagt tgaagtgtgg attttaaata gtaactctca aattttaatt
    22801 cagaaaaggt ctaaaagtaa aaagacattg ccaaatatgt ggggaatgac aactggatgt
    22861 attgtttctg gggaagacag tttagaagga gcaattcgcg aagcaaagga agaaataggg
    22921 atagatataa ctaaagatga gatgaaagtt tttagaagta tgattcatga agatactctt
    22981 tgggatgtat acttagttaa aaaagaatat gatatatcta aagctatttt acaggaggaa
    23041 gaagtaagtg atataaagtg ggtaagcaca gatgaaataa gacaattact aaaagagggt
    23101 ttgttttttg aatatccaga gatatacgaa ttgctatatg agatagataa taataaatta
    23161 aatatatgat gtagagcaga tttcagtata agtaagatta tttaaaatgt atcttctcta
    23221 aattttaata ttgttttatg aaaattaata agttattttt agtatttttc tacttgtttt
    23281 ttgagattaa aataaaaagg gcagtcatta taaagtcata aaaatttggg gaggatttaa
    23341 actatggaag ataacaaagg attggcacgt gacagttcaa aatataaaat tgtttctata
    23401 tctgtcgtag taattattct aattacattt tggtatatgt taaatatggt gcttttaaca
    23461 tttattatga cttttatttt ctataacttg cttgtagcca caagaaaacg aattaagaag
    23521 ttttcttctt taaatattcc agattcattg ataattatag tgttatatgc actatttgct
    23581 atattgttag tattgattag ctatgcagtt gtaccaataa ttataattca acttacagag
    23641 ttgagtaggg tttttagtga ttttgatgta aatcaatttg ctcaatcttt aggaccaaaa
    23701 ttgtatccta ttgtctcaaa gctggatttt aataaatata tttcacaagc agggctactt
    23761 atagcatcaa cagcaacaaa agttggaagt tttggagtaa atatattatt ggcattttta
    23821 ctgagtttac tccttttact tgaaaaaaat gaaattaaaa attttggaga taaactttct
    23881 gatagtaaga tttcttttat ttataattcg cttgtatttt ttggaaagag ctttgttaaa
    23941 aattttggtg aagtaatgaa agtacaagtt atgattgcct ttataaattc tgttgtttct
    24001 atgatttttt taggtttcat gggattccct caaatatggg ctttaggatt tatgattttt
    24061 gtgttgggtc ttattccagt agcaggagtt atagtgtctt tgattccatt aactgtaata
    24121 gcatttaata caggaggaat aacaaaggtt tttggagttt tacttatgat ttgtatagtg
    24181 catgcagtag aaacatacat actaaaccct aagttgatgt cgaatagaac taaacttcca
    24241 gtttgttttg tttttattat tttacttgta ggagaacatt atttaggtgt atggggatta
    24301 ctaattggag ttccaatatt tatgttcctt atggatattc tgggtgttaa atttacttct
    24361 aggtaatata ttaaaataat aattattttt tatatataaa ttatgaattg ttttaaaaaa
    24421 gaacctataa atagacatca ttaataaaga catctatttg ataggttcaa ttttgctttg
    24481 tataaatact ataaaactaa ataaaaagaa atttatttca tttcaaaagt ttcacaactt
    24541 gcatttcttt catttatatg aactttttca gctttgcaaa gttcattttt attgtattta
    24601 cattttacag cttcacaatg aatgttatct gtatcaactt ggttagtttc attagaacga
    24661 ctagttatac cagatgtata tttgtcttca aaagaagcac aataagtatt ttctgtagta
    24721 gttgcttgca ttccatctac ttttatacta ccagcataac aatatccact agtattataa
    24781 gcacaattag tagcagcaca atttaaatta ttatttttca taaataacct cctaagtttt
    24841 atttaaactt attatgtgaa gttatctaaa ttttatacac ttatttacaa ttacatttat
    24901 cacatttaac aactacatct ttggaagttt cccttcctaa atttttatta acatgataca
    24961 catcaacatt ttcagttgat ccacatatag aacatttaaa attgttttct agtagggttc
    25021 tttctttaaa taacttccaa tacatagaat tgatgtaatc attataattt accttgaggc
    25081 atgtctcaag aaagtttatg tatagattgt ctaaatctcc tgtatttaat tctgtatatt
    25141 ctggttcaaa atattcacaa catcctctaa aatcgggctt tgtatctgaa ataacacatc
    25201 taatatcata tctatagtct aggctaggcc ccttaaatga aagatgtgtg caaaaagaac
    25261 aagatgtttc tggtagattt ttttcaagtt catgtaattt attattcata agtattcctc
    25321 caaaaaattt attttaagta tataaacgaa tagattattt taaaactttt atttatttat
    25381 ttatattaga gatttaggat aaatattcca ataaggagta aatacttaag tatttattac
    25441 tgtattaaat aaaaaagagg caaatctaac ttgagattgc ctactttttt atcatttttt
    25501 aataaaattt attctaagta ttattttatt tagatttagt cagccaactt agtatctgct
    25561 ttgcttttta actttctacc agagcgtaca gttaaaatag catataatac agtaaatatg
    25621 gcagctaaaa catatgatat atttatgttt aagttaaatc caatttgagc attaaatata
    25681 taactgaata taacaaagga ataaaacata ccaggaatta agcttataat ataattcttt
    25741 tcttttatta taaggtaaac tgtaatcatt gcaaatgcaa atatggcaat agtttgatta
    25801 ctccaagaga agtatctcca caatatatta aatccagaag cactaagctt tgcaaatata
    25861 aggatggcta tgacaggaat aaatatacag attgacaata taacacgatg tttcttttcc
    25921 ttttggtcat aatgaaagta atctgcaagc attaatctta aagatcttaa agctgtatct
    25981 ccagaagtta ttggtaaaac aattacacct attatagcta tgataccacc aatagaacca
    26041 agtaaatctc ttgcaaccaa acctattaca tcaggagaac ctactaattc tttaggtatt
    26101 cctttattgt aaatacccat agcagctgca gcccaaatca ttgcaattaa accttctaaa
    26161 atcatcatat tataaaaagt agtttttcct tctttttcat ttgaaactga tcttgctata
    26221 agagtagctt gagttgagtg gaatccagaa acaataccac aagcaactgt aacaaagaat
    26281 gtaggaataa gaggaatacc atcaggatga atacctttcc aatttgcaag acttaaatta
    26341 gctaaatcat aaccttgtgt aaagattcca attccaacac cagcagcaga taaaagtaga
    26401 atagctccaa atattggata tacctttcct atgattttat caattggaaa tagtgttgca
    26461 cacaagtaat atagaaagat aagtccataa actatccaga caactggatt atttatagtc
    26521 gatttcatat ttaaaatttg agtaacaact aaatccccag gtgtataaat aaaaactgca
    26581 ccaactaaaa gcattaaaag acaaaggaat atattataga cttgaaatac tttattacct
    26641 aaaaatctac tgataagaga aggcatttgt gctccttttt ctcttatact aatcattcca
    26701 ctcatatagt catgcaaagc tcctccaaat acacagccaa taggtattag tatgaatgct
    26761 attggaccaa acaatatacc ttggataggt cctagaattg gtcctgtacc agctatatta
    26821 agcaactcaa ttagactatt tttccatttt ttcattggga catagtctac tccatcactt
    26881 tgagcaagtg caggtgtttt tctgtcatct gggccaaata ctttttcaca ataagcacca
    26941 tataaagcac ctcctattag taatatagcc aagccgatta agaatgttgt cataatatca
    27001 ccccatttat aaaatttttt ggtctttgta tacatattat ctaaatgtgt agatttatat
    27061 tgaatttaat tctggacaac ctacaaattc tataaagtat tacaactaat ataatttcag
    27121 aaataaatac atatacataa ccatgtactt agtatacagg tatttggtaa tattttcaat
    27181 gttatagcaa taaagaatat aaacaaaatt ctgataatat tttacaaaaa aattaaaaaa
    27241 tataaaaatt agtttaaata gatggagaaa aaaggaaaat caattgagaa tataaatgtc
    27301 tatatcttaa caatattaag aggtttaaaa ttcttgaaga aagaatagtc aagtgatata
    27361 atgagtttac aggtgtatat acactagtac atatagaaag cggtgcaatt atggataaag
    27421 atttaacata tcaaatcaaa gagctaaaga aagaaaaaaa tgcaataata cttgcccatt
    27481 tttatcaacc accagaaata caagaattag cagatgcagt tggtgactca tattatttaa
    27541 gtgagattgc tagagattgt aaagaagaag tggttgtatt ttgtggagta aggtttatgg
    27601 gagaaagtgc taagatatta tcacctgaaa aaactgtatt gatgccagta agtaacgctg
    27661 ggtgtgctat ggcagatatg gtagatgaag aaggcgtgat aaaattaaaa caacagtatc
    27721 caaatgcttt ggttgtatgt tatataaact ctacagctaa agttaaggca cattgtgatg
    27781 tttctgttac atcttctagt gcaattaaaa cactagaaaa catagataat aaagaaatta
    27841 tattccttcc agataaaaat ttaggaggat atattgcaga acaatttcca gataaaaact
    27901 ttatattttg ggacggatat tgtaaatacc ataacaatat aagagctgaa gaaataattg
    27961 agttaaaaga taagtataaa aatgcagaag tattagtaca tccagaatgt aaaaaagaaa
    28021 taagagattt aggagattat gtaggtagta catcaggaat aataaaatat gctactaata
    28081 gtaaaaacaa agactttata atagcaactg aagaaggtat attacatgaa ttaaagaaaa
    28141 ataatcctaa taaaaacttt tatattcctg gtggaaaaat actatgtaca gatatgaaaa
    28201 agacaacatt agaaaattta tatagtacac ttaaaaatat ggaaaatgaa gttattgtag
    28261 aagatgaaat catggaaaag gctttaaatt cactgcttaa catgcacaaa ttagcagaag
    28321 gatagaggga tagacttatg aatttagaac aagatgtttt aatagttgga agtggagttt
    28381 caggattata ctgtgcatta aatttagata aaagtttaaa tgtgctagta gtatcgaaat
    28441 caacaattga aaacaacaat acatatcttg cacaaggtgg aatttcaact gctagaaata
    28501 ttgatgatat agaatccttt gtagaagata caatgaaggc tgggcagtat aaaaatagag
    28561 ttgaagcagt tcaagtactt gcagatgaat ctatagaaaa tgtaggtcag atagtagaat
    28621 atggtatgcc tttagacaaa gaaaatggag agatagatta cacaagagaa ggagcacata
    28681 gtgtaaatcg aatagttcat agtaaggata atactggaga agttgttttt aaaactttat
    28741 taaaagaagc taaaactaga gaaaatataa ctcttataga agatgcatat cttttagata
    28801 tattaaaaga tggcaataaa tgtataggag ctagaatttt taaatctaaa aaagagattc
    28861 atgttttttc aaaaatagta gttttagcta caggtggaat tggtgggctt tttaaaaatt
    28921 ctactaatca aagacatctt acaggtgatg gaattgcaat agctttaaga aataatataa
    28981 aaatagaaaa tttagaatat attcaaatac atcctacagc cttttatgaa gaaaataatg
    29041 aaggtaggag aatgcttata tctgaatcat taagaggaga gggagctaaa cttttaaata
    29101 aaaataaaga aagatttgtg gatgaacttc ttcctagaga tgtagtttca aaagctattt
    29161 ttgagcaaat ggaaaaagat aaattacctt atgtgtattt agatgcaaca catttagata
    29221 gtgaatattt aattaataga ttttctttta tttataatga atgtttagct agaggaacag
    29281 acataacgaa agaatgtata aaggtatctc ctgcacaaca ttattttatg ggcgggatac
    29341 atgtagattt ggattcaaaa acatctatgg aaaatttata tgcagttggt gaaattagtt
    29401 gtacaggtgt tcatggagcc aatagattgg caagtaattc attacttgaa gggcttgtat
    29461 tttcaaaaag agcagctaaa aatataaact cagttataga taatgtaaaa gttaagttta
    29521 tagatgtacc agatatggat atagatatag aacaggtaaa aaaagaaaat aaaatattag
    29581 tcataaaaga aattgaaaga acaagtgagg attttggcga tgaattattt gattattgat
    29641 agaatgatac aggatgcttt gatagaagat gttccaagtg aagatataac aactaattct
    29701 attgtggatg aaaattctaa atctactgta gatttaattt gcaaacaaga tggtataata
    29761 gctggcttag gtgtatttaa gagagttttt gagatacttg gtgatgtaga tgtaaaatta
    29821 tataaaaatg atggtgatag agtaaagaat cgtgaaaaga tagctgtatt aacaggtagt
    29881 actagaaact tacttgtagg agagcgtgta gcattgaatt atttacagag aatgagtggt
    29941 atagctacta ttacaagtag gtatgttgaa aagcttgaag gtacaaatac aaaattatta
    30001 gatagtagaa aaacgatacc taatcttaga atattagata agtattctgt caaagtaggt
    30061 ggaggatgca atcatagatt taatttatct gatggaatat tgcttaaaga caaccatatt
    30121 ggggctgctg gtagtgttaa gaaggcagtt gaattagcta gaaaaaatac ttcttttgtt
    30181 agaaagatag aagtggaagt ggaaacttta gacatggtaa aagaagcaat agaagctaat
    30241 gcagatataa taatgttgga taatatgagt ttggaaatgg caaaacaagc agtagatatt
    30301 ataaatggaa gagccattgt agaattttcc ggaaatgtaa atttagatac tatagaagat
    30361 ataggaaaaa ttggtgtgga tgttgtttct gtaggagcgc ttacacattc tgttaaagct
    30421 ctcgatataa gtatgaagaa tttgagaaat atataaattt tatattgaaa taaacttaat
    30481 taaaatagac tccttaaatt tgttttataa at
//
LOCUS       DAEPUT010000044        30485 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.045, whole genome shotgun sequence.
ACCESSION   DAEPUT010000044 DAEPUT010000000
VERSION     DAEPUT010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30485
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.045"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(35..571)
                     /locus_tag="KRL22_002192"
     CDS             complement(35..571)
                     /locus_tag="KRL22_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBH1272681.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(589..1902)
                     /locus_tag="KRL22_002193"
     CDS             complement(589..1902)
                     /locus_tag="KRL22_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HBH1272682.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2257..2697
                     /locus_tag="KRL22_002194"
     CDS             2257..2697
                     /locus_tag="KRL22_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH1272683.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2882..3070)
                     /locus_tag="KRL22_002195"
     CDS             complement(2882..3070)
                     /locus_tag="KRL22_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1272684.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTIIKNSNKKE"
     gene            4037..4432
                     /locus_tag="KRL22_002196"
     CDS             4037..4432
                     /locus_tag="KRL22_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272685.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNNTCTTE"
     gene            4475..6574
                     /locus_tag="KRL22_002197"
     CDS             4475..6574
                     /locus_tag="KRL22_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBH1272686.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTIGNMIPLDGVIVSGEAMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIILKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(6799..12009)
                     /locus_tag="KRL22_002198"
     CDS             complement(6799..12009)
                     /locus_tag="KRL22_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBH1272687.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLNEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKRLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNALYEEHKDWTISKREDSGSA
                     GAEGKAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNTKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDIKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNRKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12024..14519)
                     /locus_tag="KRL22_002199"
     CDS             complement(12024..14519)
                     /locus_tag="KRL22_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1272688.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEITKYDEVVKVFKNWLESTTSLTIER
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(15156..15443)
                     /locus_tag="KRL22_002200"
     CDS             complement(15156..15443)
                     /locus_tag="KRL22_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272689.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(15463..15738)
                     /locus_tag="KRL22_002201"
     CDS             complement(15463..15738)
                     /locus_tag="KRL22_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272690.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(16374..16553)
                     /locus_tag="KRL22_002202"
     CDS             complement(16374..16553)
                     /locus_tag="KRL22_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272691.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGNAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(16838..18313)
                     /locus_tag="KRL22_002203"
     CDS             complement(16838..18313)
                     /locus_tag="KRL22_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1272692.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLL
                     TYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIG
                     DCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYVTLFSEYDDDYINTEE
                     GAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDF
                     VLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYL
                     KKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRLKLGIL"
     gene            18908..20086
                     /locus_tag="KRL22_002204"
     CDS             18908..20086
                     /locus_tag="KRL22_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1272693.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFGNKNITIHKNYKYIFL
                     IKPLIFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYRLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHHRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVPSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
     gene            20436..21317
                     /locus_tag="KRL22_002205"
     CDS             20436..21317
                     /locus_tag="KRL22_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1272694.1"
                     /translation="MPAYLFDSNSITNIYRVFSILLSFIVTGLYFSYKNHKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            21526..21675
                     /locus_tag="KRL22_002206"
     CDS             21526..21675
                     /locus_tag="KRL22_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008819224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1272695.1"
                     /translation="MTTVAEGIETSFQKYFLQEIDCDMLQGYVFSRPLPIKDFEKLMF
                     QNSSN"
     gene            complement(21935..24502)
                     /locus_tag="KRL22_002207"
     CDS             complement(21935..24502)
                     /locus_tag="KRL22_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH1272696.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEEVSKKIGELFHNGEMPQEVSDAIKTAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNCASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRAIKSGQMITVDGLAGTVTFDE"
     gene            complement(24505..25110)
                     /locus_tag="KRL22_002208"
     CDS             complement(24505..25110)
                     /locus_tag="KRL22_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1272697.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRSVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPSDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(25484..26944)
                     /locus_tag="KRL22_002209"
     CDS             complement(25484..26944)
                     /locus_tag="KRL22_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH1272698.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGALNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            27282..27860
                     /locus_tag="KRL22_002210"
     CDS             27282..27860
                     /locus_tag="KRL22_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1272699.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIERHNLKLKIEKEKVFGVCNA
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            28151..29401
                     /locus_tag="KRL22_002211"
     CDS             28151..29401
                     /locus_tag="KRL22_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1272700.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHIFFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            29562..30131
                     /locus_tag="KRL22_002212"
     CDS             29562..30131
                     /locus_tag="KRL22_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH1272701.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT        10270 a         5225 c         3710 g        11280 t
ORIGIN      
        1 atatatttta aattttcttt tttaataaat ctatttaatt ttcttcttct atatcagagc
       61 caaagggaat ccatgcatta ccaaactctt tatctttaaa taaataagct aatccagtta
      121 tttgcttcaa tctaagaatt tcatcaactt ccatacccag gtgctttgat atccattcat
      181 cagattttcc aatttcacaa agttcagtta taattttact cattaaatcc acattatgag
      241 aacctcttgc acgattgtgt cgaatagtac ttgccattct ttcatcaaga gatttatcaa
      301 ttactgaaac aggaagaagt ccattttctc tatcatatat atcctcattt tcaagcatta
      361 ctctatatct atgaaaacca tctacaataa tatacttatc cttttcctca ttataataac
      421 agacaattgg cattgtatac ccatcttctt ttatactttt atacaacaac tgcatttctg
      481 gtggggctac tgcatttgga ttatagtcgt tagattctat cttttcgatt ggcactgcga
      541 tgattccata tacaggactt ttatattcca tagcatctta actcctatct aatgaatttt
      601 ttcatatttc ttcttaatat attccgttct aattctctgt tcttttgtag gaccaaatcc
      661 cataaatcta cacatatggt cattttttaa aatacaataa cacattcttt tccaacttgg
      721 tatatctttg gtaaatttaa tatcatccgt atcatcaggt atatcatcca aaaatatgac
      781 tctactcttt ttatcttttg tatgatttga aactccattt aattctattt tataaccttt
      841 tctcaacaat tcacgtataa ctatttctga caaaccacca cctgtattct gccaaaactc
      901 aatagatgtt gaaaattttt taatatagct attccttata ttttcaggta aggtatcaag
      961 caaaaaatat gtgaaacttt tccatgtgtg tccatatggc aatttaacac tacgatatcc
     1021 catagctttt gttttgccat aaatagaagt aaaattaact ccttgtactc tagcaaccaa
     1081 tttcacccat acatctgggt ccaatattct gtataaattt aaactctctt ttgctgaatc
     1141 attaaaaggt gatgccactc tcatttttct tggagctact ccagctttat agaacaagtc
     1201 ataaatttta ttatagtcat agtcaaattt atagtgtgct aaccatatat cttctatttc
     1261 ccaatcatat ataggagatg ccgtccagac atttttaaat tccttagtta tccagcactt
     1321 tcctttatat ccatgctgtt tattcacaat agaacaataa cgttgtagag attctgctgc
     1381 tcgtgttcct aataagcaaa caacttttgc accttcatgt atatctctaa tccatctacc
     1441 aaattgtttt gccaaacttt cttgtctcat tttatattta taataagtaa aaggattatt
     1501 tttttgattt attatgtatt ctttgactgg catttctctt acccataact cttctttctc
     1561 atcatcccat ggataccaat acatttcata atttcctaca gcagttcttg tagccattgg
     1621 taaacacacc caatatggtt caatatcttc aatattatct tcaaatactt tttcaacata
     1681 ttcagtagtc aaactatatt gagcctcaaa atcttgatga aatactccta ttttggaact
     1741 tatattattc tttctcttat aatccaaaac taaatttagc agtaaaccac tatcttttcc
     1801 tccgctaaaa gatacataga tataatcaaa ttcattaaaa agataagaaa gtctttcttg
     1861 aaaagcttca aatacatcgg attctaaata tctcttatcc atttgaatta tcccctttca
     1921 attagaagtt tataaaacct tacaatgcaa tattattatg cttttttagc agtaatcagc
     1981 ataaattata cattatttaa atacacaaat ccaactaaat acatataatt ataatgtaat
     2041 tatacttttg tattataaac tatattttat cattatttta catttttttc caatatatat
     2101 aattatcata tttttctatt agctaaaact aattacctta tatttttatg tattggtata
     2161 ataatacata aaaacttgaa taatgcataa aaacttgaca tactgttgtc ataattactt
     2221 tgctataatt aaaagtaaaa atggaggtaa attctaatgt atgaacgtat gcttgataaa
     2281 agcaataaac cctgtttgtc ccaaataata gaatatatag gtaaggatgg atatgcacga
     2341 ttatgtaagt tggaaactta cttgaaaact caatataatt tatcaagaga acttcgattt
     2401 ccttttggaa acaattatgg ttggggttac aaatatagcc ataaatcttt tcatttattt
     2461 tatgcttttt ttgaaaaagg tgcatttact gttctgattc agataggtga caagcaagtt
     2521 ccagcagtag aaaaaacgtt ggtagctttg acaccaaaag ctaaagagct ctgggtcact
     2581 cgttatcctt gtggcaataa tggaggttgg attaagtatc gtattttaga agatgcagac
     2641 ttacttgata ttattcaata tataagagca aaaaaatctc cacctaaaca aaattaactt
     2701 ttattttttg tgatttaaat atagtgtata taaattccat tctttccata taaaaaaaat
     2761 aatataaaaa atatctatta gtataactca tttagtatgt cttattctac tttttacaga
     2821 taattaaaaa gttttatcat aaataaatca taactagaca tcctagtaaa tcaaaattaa
     2881 tttattcttt tttattcgaa tttttgataa tagtccctat acatatgcca attatcattc
     2941 caaaaattag accataacac attgtgatac ctacatttcc tttagaaata cctatagcac
     3001 aacctatagc cattccaagt atcatgccta taaacataca tataataact aaattgttgt
     3061 ttttattcat agtttttctc cattcaatat attttaaatt gcctagctcg ccttcttagc
     3121 ttaaaacaaa gaaatataaa ttaactttct ttcattctaa tatctgcctg tataaatgtc
     3181 aaacaacaca tttcttgtca taacctcctc tttttgaagt aagtacaatc tcccagacgc
     3241 aataatatca atttcctaaa accatttaag taacttttat atttacataa tatttacaat
     3301 cataaactat atttttattc atttatacat cataaacact ccctactaat cattattata
     3361 cttaaaataa tgttcattta taataatata tctaacacac tttaattgaa aaaaataaaa
     3421 ctttgccttt cattcccata tataaataag tatacttttt gatgctctat tacaaatcaa
     3481 ctaaattaat tgatataaat tatcattttc tgttgaaaat accattcgca catgctatac
     3541 ttaattgcat aaatggtaat aaatgtcata tgattttaca aatctattaa taacaattat
     3601 tacttttact gtattttaaa gtttttggac taaatatcaa gaactttcta aaatacaaag
     3661 tacaaaaaat ttatataagt tataaattta tatgaactag ataagctcaa acaatatgtt
     3721 atgtataaac tgtgtagtat tcggttataa atttatataa attatataag ctagataaag
     3781 tattacctca actatataag ctagatatat aaattacata cataagctag atatataaac
     3841 tgcatatata agctatataa gaattatttc aactatataa actacacatg taaaattcat
     3901 gtaaatttac taatataaat caaataaaat tactaaactc tctaaactaa ttttgtaaaa
     3961 catactctat ttttaacatt tgttacctta tacataagta caaacaaaat ctaactaaat
     4021 gaaaggataa tgtaaaatga atattttaaa aatgaaaaaa acagggatat ttttaggagg
     4081 agtacttttt ggtactgtag gtgttaagat actttcaagt gattgtgtta aaaaaacttg
     4141 cactcgtgca acagcaggag cattgaaagt taaagattct gttcttgaaa caactacgaa
     4201 aattcaagaa aatgtagaag atattttagc tgaagcaaaa gaaatcaacg agcaagaaga
     4261 cttatctaca tctaaggtaa acgttgtaca agatactctt aaatgcgaac aagaagttct
     4321 taaaactgaa actataaaaa ctgtagaaga tactaattct aatagcatta aatgtgaaga
     4381 aatcaaagat aacgtaattg aagaaaaaaa taatacttgt acaacagaat aaatttaatg
     4441 attattatga ttaataatat caggaggaag taaattgaat ttttatataa aacacgaaat
     4501 aagaggtcgt atacgctttg acttacaact tggcaaatta aacaacaagc agtccgatac
     4561 tctcttatat tatttaactt ctataaatgg tattaccaaa gcaaaagttt acgatagaac
     4621 tggtgatgca gtcatttatt acactggtga aagagaatac ataataagag aaatcactaa
     4681 attcagtttt aacaatagca aaatagaaaa cctagttcct gaacatacca gcagggaatt
     4741 aaacaattat tatagagaca aattagcaaa taaactgcta gtcaaaagta tctccaaaat
     4801 attttttcca aagtccttaa gatttttttt aattggactt cattctataa aatattttaa
     4861 aaaaggtctc tcttccctgc taaataaaaa aatagaagtt tctgttttag atgccactgc
     4921 tataggtatt tctattttta gaaaagatat caatacggct ggttcagtta tgtttcttct
     4981 tggtatcggt gaactattag aagaatggac tagaaaaaaa tctatagacg acttggctca
     5041 aagtatgtca ctaaacattg aaaaagtatg gttaagaaaa ggtgacactg aaatcttaat
     5101 tccaatttca gagataaagg aaggagattt agtaagtgta actataggaa atatgattcc
     5161 attggatgga gttatagtat caggagaagc aatggtcaat caggcatcac ttacaggtga
     5221 atcccttgcc gttaacaaaa aagaaggatc ttacatatat gctggaactg taatagagca
     5281 aggcaatatt gttatgtgcg tcaaggaaaa agctggtact actagattcc agaaaatagt
     5341 aactatgatt gaggaatctg aaaaactaaa atcttctgta gagagtaaat ttgaacatct
     5401 agcagataca ttagttccat acagcttttt aggaagtata ttaacctatg caattactag
     5461 aaaccctata aaatcactct ctatattaat ggtagatttc tcttgtgcat taaaactctc
     5521 tatccctatt tcagtactat cagccatgag agaatgtaac aataacaaca ttactgtaaa
     5581 aggtggaaaa tttcttgaag gtgttgcatg tgcagatact attgtatttg ataagacagg
     5641 cacattaaca aaagctcaac caactgtttc agatataatt acattccaaa attataataa
     5701 ggaggatatg ttaagacttg cagcttgctt agaagaacac ttcccacact ccatagcaaa
     5761 tgcagtagtt tacgaagctg aaaaacaagg gcttagtcac aaagaaatgc atacagaggt
     5821 agaatatatt attgctcatg gcatttcaac aaaagttgat gataaaaagg ttgtaatagg
     5881 tagcaaacat tttgtatttg aagatgagaa gtgtactatc ccagacggtg aggaggataa
     5941 gtacaacaat ctatcagatg agtattcaca cctatttatg gcaatatcag gtaaattatc
     6001 agcagttatt tgcataaatg accctttacg aaaagaagca aaatatgtaa tttcaaattt
     6061 aagagaatgc ggaataaaaa agattgtgat gatgactgga gatagcgaaa aaacagctaa
     6121 atctatagca agtaaagttg gtgttgatga atattattca gaagtcttac cagaagacaa
     6181 agccaatttt gttaaaagtg aaaaactaaa aggtcgcaaa gtaattatga ttggtgatgg
     6241 aatcaatgat tctcctgcta tttcagaatc agatgtcgga attgcaatga gtgaaggtgc
     6301 tgaaatagca agagagattt cagatattac catatcagca gataatttga ataatttaat
     6361 cattttaaag cagattagta ataagcttat gaaaagagtt gatttaagtt ctaagtttat
     6421 tattggcttt aatttaggtc tgattttact tggtgtcggt ggatttgtta gaccaagtac
     6481 atctgccttt ttacacaacg catctactgt cggaataagt ttaaacagta tgacaaattt
     6541 attggaaaac accaatactt ataactacca ttaatctcca ttacataaaa catatgatat
     6601 aaaaaattta taattcatct tttaaaaaga atatgtctta aaattagctt ttttctaatc
     6661 aaaattatat aaagcatact ttacaaattt taaactcaac ttatttctat tttttacaaa
     6721 aaaggagatg attcaaattt tcattttgaa acatcccctt ttgtaaattt ctttaaaatt
     6781 tatatattaa ttatattttc aaccaataat tgtattttca accaatcttt cttcatagca
     6841 ttttaaatca ttttgcttta gataattaaa ttcagactct acataaatac cacagcctac
     6901 caattcaatt gtcaaattag gtatattttc ctttagtata ctagtctgct cataaataat
     6961 tctttccaat aaatcaactt gtaatataga aaaatgcttc ataatctccc catcactatc
     7021 tatatctttc ttgatttcat accaactctt tgacaaaatt cccttcaaat caatataccc
     7081 tagactcctc aatatatcta tactatcgct ccatgcatac ttactaggtt tatcaaagta
     7141 tgattctagt ttcttcttct gctcatttgt aagtgaatca taagaaagct tcctattaaa
     7201 atgtgccttc aaagaaatct tagccataga atatggactt ctaccagagt ttaatcctgc
     7261 atttttgaac ttttcaattc ctttatcttc tactgaagac catattgagt ttattgaatc
     7321 tgaatcattg tatttaatat caagaccatg tgtaatattt atatagtttt gtggaaatac
     7381 atattgataa tagacatctt ttttatcatc atatagagag aagtatccac tatcatataa
     7441 atgaatatgc acctttactt ttaaactatc ctctaaaata tttcgtctaa ggttcgggat
     7501 atttgcatac atggttacat attttatggc atcaaagttt ttatttaatg gaacttcaaa
     7561 actaatttca tctcctgtca aaagcttttt cacttcttct tcattacaat catatagaga
     7621 atatgtattt tcaaatccca cacgtgattt cccatctaaa ctgcctgtta atgctacctt
     7681 caaaatatgg ttatctgttt tttgccattg gtaagcatct tggtcaagaa actctctaat
     7741 ctgtctattt tgctctttcg cctgatttat aacctcgttt tcatcttctg taatccctac
     7801 atggcatcta tttaagatat ttactatatt gcttccaaat gggaatgtcc atagttgaaa
     7861 agctgctgcc tcaacctgac acaaatatct aacctgattt aattcaattt gatggataag
     7921 ttttttctga tattcattca tctgattacc actatctgac atttgataaa tcaattctcc
     7981 cattgcaaga ttatcttttt tcttatcaat cttatcagta atgataattt gagtttccat
     8041 catatcctgt acttttttaa atattataga aatctcctct gaattttcca tttttaagct
     8101 tccaaacttt gtgcttaatt cagttaaaac ttccttcatc tttaatttac ttatctcatt
     8161 ttcaaaaata tcttgatttt taactgtact atcaaatttt tctacaaatg gtataacaga
     8221 ttctttcaaa gttttatctt taaattccac catttgagta ttcaattcat ctaatttctt
     8281 aatattattt tctttatctt taattgcctc tttaactacc tctattttac tctcaaaact
     8341 agattttaca ttaagacaat tattaacacc actaatcgca gtatttataa gagaacaagc
     8401 agaacttcca atactcaatg catttttaat tttagatgtc ttttgctgtc tttcaatagc
     8461 ttgtttactt ttctctagtg cagctaactt atctttttgc tgtttattat tgtaatttgc
     8521 ctccaacata cctatttctt ttttctggat ttttgtgtaa atttccttat actcactttc
     8581 acttaacccc tcttttgctc tttgaatatc gtcagctttg tctgcataat tatcatcatc
     8641 tatagactta actataatct ccttaatttg gtcaaattta gttcttcttt cttcatcaac
     8701 acctgccaaa ttataagtca ttttatctaa agcatttttt ctatcttcac ttagctgttc
     8761 tccaagtaca aatctcatac catcagaatc caatttaaaa tctgaaaaat caaccatcct
     8821 gttggtccat tggtattcct cttctttagc tgaaagattt tccttcaaag attttgcact
     8881 gtcaaatgcc cctagacaag cttgaccaac accactaaat gcagtcagta aactcaatgc
     8941 gctttgtatt ccagaaagaa ttaactgtgt tttcatttgt tcctcaagtt ttgcctgttt
     9001 cttttttagt tcctctatgt cttcttgttc atcttctttc atctttataa tttcttgaat
     9061 caacaggttc atttttgcat taacagaaag cattttattc tcaagttcat tttttaaaac
     9121 ctctatttgt tgatttccag attcaatttg agttaggata ctttccttat atgtattgaa
     9181 atatccttct tttaactcat ctttcttccc ttgttccaat tctcttaagg tcttatccag
     9241 ataatctgtc aaagaacgaa tatctgtaac acgatttcct ccaatttcac tttcttcaat
     9301 catctgcaca taaaatgctg tcttctgctc aagtgcaaat aaaatcatac tccattcgct
     9361 aaaattctga ttttttccta caaaagattc tattctatca gactgcatca atttatttat
     9421 aaggtattca tagatttcct ttgcttcttt ataaaattct ttctttgtat tcatatcatc
     9481 cagagaaagt actgctttat ttttcttctc aaaactatag tacttctgaa gtatttctct
     9541 atttaattgc atctctattt tctcaactgc atgaaaaatt tcataaatat gtgaaagttc
     9601 taaaatatca gcttctaaaa ttcctactgc acacaacagt ctaagatttc tataaccttt
     9661 aattccagaa aaaccaaatc tctcgaaaaa ttcatagaag aatgtatcta ttgacaaaga
     9721 atactcctgc tttaacaatt ccttttcttt tagtgcatct ccagagtgac cggcttttcc
     9781 ctctgctccg gctgaacctg aatcttcacg tttgctaatt gtccagtcct tatgttcttc
     9841 ataaagagca tttaatttct ctccatcatc tgctgcttgc ttctgattta aagcatgatt
     9901 aaacacatat ctatcaaaat aatagtagtt tctatcacta ttatccattg gaggagaggt
     9961 acctatatat cttattgttt cttcatatat acctctaatt ccaccaagac ctcctgcacc
    10021 accagctcct ccagagcctc cttttcctgc taaaccatga tttccatctt ttttacttat
    10081 agcacttttt aataaaggag cttttccaag gagataaacc tgtccagact tgcttccaag
    10141 acctgcattt ccaccattac ctcctgtgcc tccagttcca ccttgttttc ctttttctgc
    10201 ttttaccaca tagtattttg tacctttaac attagcaaat tcttttgact cttttttaga
    10261 acctatttta gcatttgccc cagcttctcc agttatccct gtatctcctt tttttccatc
    10321 ttgtccattt ccaccacgtc caccatctac gtaaagttta agttctcctc ttttttctat
    10381 ttctttaaaa gataatatga tatcacctga agtacctgca ttattgccat ttcttccatt
    10441 catcccgtcg taaatagaac tttctccaac caatttttct gcatccttac cagatacgtt
    10501 gattgaataa gtcccttctg gtatatgtaa tttttctgta agtagtacaa tattcttacc
    10561 tgagaagact tctttctcca tattacagtc aattttcaac tcacaatctc catacatata
    10621 tatagatgac aaaatattaa gttgataacc agatattatt ttagtcaaat ccgataaatt
    10681 cactttaggt ataggaatat atatagaaag tacattttct ttctcatatg attttatata
    10741 tgtacaactt tgaatcttct ctatcctata ctctgcatct tcaagccttt tggcttcttc
    10801 ttccctatat tcttcttctg ctatccaata tttgatatct ttcaatgtat cttctaaagt
    10861 attttttagc aatgatttta acaactcact tagaccaaca atatgagtct cactacagta
    10921 actatttaac tctaaaagaa gacgtgtttc ttctaatata ttcactttct gtacgccatc
    10981 accatatgaa agttcttgta caaactccat aagctctttc atattattag tcctactaca
    11041 taaatctgta tacatcttat ctaattgaat ctttttatct tttagactat ttatagaaga
    11101 tagaatggaa atagaatctt ccataccttt tttaacactt tctatataag gaactaaaag
    11161 tttttctagg tctttatagg ttacatcaac agctttttgt atttctattt tacaagaagc
    11221 agtaagcatc aatcccaaat ctgttttttc aaatgtttca ggtagatttt tcatttcatt
    11281 caacaacttt tctggctgtt tatctagtgg attacataat ttaatagata caccatctga
    11341 taatgctaca tttaataagt acactaattc cttacaaccg tcgtaatctt tctcttgact
    11401 atctaggtct tcttttgctt tttccaatat atttcttatt ttttcttctg ttacattacc
    11461 aattagtgtt ttaggtattt tattgataag aaagaagaaa ttttctttat actttgcata
    11521 atcaccaagc atatctttca aatttttgcc tgtttctatc aataatgtat gtctagagtc
    11581 cagtagggat tgatagtcta aaataactac catccctttt acctttgaag atgtggaaat
    11641 agtttccctt acaagcatag caccagcaat catatactct gctccacggt tgtcaaaaaa
    11701 acctgggcaa tcacataatg aaaaatctct atttgcaata tctacaactt ctggacataa
    11761 agtcttagaa tatacaccat ttccaatttc gacagctgaa tcttttgcag ttatatatat
    11821 ttgtccagtc tcttcatccg ttttttcttc catcacacag ccttttaaat aatttataca
    11881 agtactcttt ccaacgcctg aagcacctag gaataacaaa attgactttt cttttaagtc
    11941 atattttcta agctcgtctc ttccttcttc caaaaggttt acgatttcac tataaagttt
    12001 atttgccata catccatccc tttctatatt tcggaacaat agccttgata tttttcttta
    12061 ataagattct cttctacctt tgaaacagct gttgataact tagtatttgg agcattaaat
    12121 cctccattgt ctcctctatc tccatattca gcgtattctc ttgctggtcc tgttttacct
    12181 tcattccagc ttccaccact aaattctata tgatatttaa ttatactatc taacttataa
    12241 tcccaacttg taaaatatcc tgtatagtat acagtcttat ctataccact tggagaaaat
    12301 gaaagtgtat tatatccgtg atagccacca cttcctccat atccacctaa acctggtcta
    12361 ccatttggac ctgcttctcc atctttcact gttatatcac aatgattaat tattctattt
    12421 ttttgttcct ctgaatctga aatgaagtaa atattacctt tcttaccagc atttccacct
    12481 cttccagcat ttccaccagc tccacctttt tcaccttttt tgccacttgt acctttttca
    12541 aaataccctt taaacatctg tccgtggaaa taacttgtat atcctgcatc agctccatta
    12601 cttccagaag ctcctgtttc accattttct ccatctattc ctttagaacc atttcctcca
    12661 tttgcaatca gtgttagacg ataatttcta atttcttctt taatatataa gtaaatatta
    12721 cctgcatctc taccatcttc accatttttc ccatacatag aattatctac aagttctccg
    12781 ctctttccac ttacattaat ttttacatta ctacctacat caagattgtt agaagcaaga
    12841 ataatatttt tctctgatgc aaagttcatt ccaaggttat catccatata aatagtatct
    12901 ttagcaaaga acataaaagt agaaacattg tcatctactt ttctattttt gaaatattcc
    12961 aatacactgc taattactaa gtttggaatt aatgctctta tttcaatacc tttcttatca
    13021 ttaatattaa ttgtttttac tataaatgga tttaaaatgt atttaccaat aaattctcta
    13081 attatctcat taccttcttc tccatatgca cttaatcttg ttatactgtc ttctaactct
    13141 tcattttgtg taactgtaac atttgtcaaa attgaattaa aatcacttac actatataca
    13201 taatcctttt tatttgcaac ttccattaat ttttctctat ttggtaatgt aaatacctgt
    13261 ttttgcactt cataagaaac taaaactttt tctaaattct ttcttattat aatgaagttt
    13321 tgttccatta tcttcttact tgccttttct ataataaatt ccatatgtac agaaggtaat
    13381 aaaatttccc cagttccatg ttctgtatat ttacttaaag catcaattat atctaagttt
    13441 ccttttatct tattttgtaa tttcatgcaa ctatcttgta agaataagcc actttgtttg
    13501 gctaatacgt tgataaatct ctctatagta agacttgttg tactttccaa ccagttttta
    13561 aatactttta caacctcatc atattttgtt atttcttgaa tcattgttat acttccaata
    13621 atattgataa aatcttctgt atacgcctta acataatctt ctaggctaga tacgatattg
    13681 ttttgaattt cttttatcaa cgtatctaaa actaatcttg catctgcact aattggatat
    13741 tggaatgctg atgtcttatc tttaacttca tctaattcta gtacttgctt taataagcct
    13801 tccctctcat ctgatgcaag tggcttacaa agatgaatat tttttccatt atcttttagc
    13861 aattcttcaa ataaccaagc tttttcctct atattactgt ctaaattttc gcataattgt
    13921 tcatattttc tttttataac attatatatt tgtttttctg ttcttcctaa gaaacttttt
    13981 gaaatgaaaa aagttatact acccttaaaa ttttctttat gaagacacat atttaactgt
    14041 tggaacaggt ctagtacttt tgtaagtcta gaatctaata tatctgcttc tggtatcaat
    14101 acaattactg cacatataga tgcagaattt ttaaatactt cacctaatga aactgctgca
    14161 ctaatatcat gggctactcc cctattgtcg ctaaaacctg cagtatcaca taattttgca
    14221 tccattcctt ctattggttt tctcatattt acaatgttcg ggtataaagt ttgagaaaca
    14281 gctcctgaac caatctctgc cacagggtct aagcaatcaa tatatgatat accagtatct
    14341 tcatcttcta cttccatcat tacacatcct gcaagatagt taattgcagt acttttgcca
    14401 catcctgtcc caccaagaat tagaattaaa ttttgatttt cagccttatt tattgctact
    14461 tttccttcat ttaataagag tgttatttct tctaaaagtt gattgttatt ttctggcatt
    14521 tattttcccc cttggttata tattttattt aaataaagtt taatccctta agtagattgc
    14581 aaagttttta gactatattt aaatttgttt tttatttttt atttttaata aatttgcata
    14641 ttcactcaat ttgcattttc actcaataat tattcttctt tgtttattaa aataactgtg
    14701 ttgtataata taatctttac caacacagtt attttattta atgcgcttat tttattgtat
    14761 tttatgtaat acagttgttt tttatattat ctgtccattg ttttcctatg gttattacat
    14821 atagattttt aattatattt gtaccattaa tttaaacatt cctatactac tgcttaagtt
    14881 ttacacctat accagcttga atattttatt tttatttgct taaatagttc aactatactg
    14941 gtttaaatag gttatcttta tttgcttaaa tagttcaact atactggttt aaataggtta
    15001 tctttatttg cttaaattag ttcaactata ctggtttaaa taggttatct ttatttgctt
    15061 aaattagttc aactatactg gtttaaatag gtttccttta gtttaaataa ttcacctata
    15121 cctacttgaa tagttcactt ttatttgctt aaattctata ccaataccgg cttaaacatt
    15181 atactaccat gattgtattg tctatcttca actacaataa aaacaggttc taaatcttta
    15241 gtagatgtta tttttaattc taaaaaaaca ttatcagttg gtaatatttt tacatcataa
    15301 ttatttaaat tattattcgt gatactatta aatacatcac cttgacgttc aaaaaaaaca
    15361 ttatcaacta ttacaaaata aacatcttct tttctactat tttcaacctc tatagtattt
    15421 tgtttagtta catttagtct catcttccac ctcctattaa tattacttaa ttatattaat
    15481 acttgtaatt gttgcattat gttcatcaca aggaagaggt ttaaaaacaa ctatctctgc
    15541 taaataattc tgtggaggat ttgtaactga agtagcattg caaataaatt taaaatttgt
    15601 tcctgctaca acttgagtag aaacaataag tggttcataa ccaacccctt ctaacattcc
    15661 tacagcttca ttaaatactt ttaaatcttc ttcttcgaca gctctgaatt ttgaccatcc
    15721 accaacaaaa agactcatat aaaaacctcc tttatatata tatttattta tatatatagt
    15781 agtaccaatt ttctcaatat tcaatatttt atgtgtaact ggtcaatgaa aatgcataac
    15841 tggataaaaa cacttataaa ataacttaac tttacatata aatagcttac tttacatgta
    15901 ataagattat tctacaatat gaaatgcatc ttgttttgaa tatattctaa atacaataat
    15961 ggatattttc aattattata attagaaaat atccattact taacttgttt tatttaaaat
    16021 cacatagaga ctttattatt tttttattgc atgaatagct atttcaggta tcataaggtg
    16081 atataccccc tccttgaaac cacaaaaaac atgacaaact ttacgaatct tggcttaaaa
    16141 gaccacaggt acattcctta tttgtggatt ggagtagcca taacaagcaa attttacaat
    16201 ttttatgatg acaaaaatca ataaaatcgc ttagtatata acacgaaaca ctacttgtta
    16261 ctattaagaa tagttagata ggaagtatgc attataccaa taaaggaatc aataaagaaa
    16321 gttaaaacat ccctacaaat taaaaatctg ttacattttt ctatatttaa acgttattta
    16381 cttacaattg gagaaataac aggttttcct tctcggtcaa gtaaaggcgt aaatccggct
    16441 gcattgccat aatagtggaa tacatagttc acacctgttt ctttatccac ccaaatctcc
    16501 gttgcattta tttttccttg tgaatatact ttttcaaatc tatcttttcc cattttataa
    16561 tcccccatat ttttgattgg tctatacctt cttcacttaa gtcgaaaaaa tacataactt
    16621 atttttttaa ttctaatatg agcacgtaaa aatgtcaaac agcttattta atttcataac
    16681 ttcatgttac tgttcgtaac cttgtctgtt tacttacact gcattacagc accattttat
    16741 cctttacatt attgtattgc acacagtaaa aatgcttact ttatgggatt tttcaactaa
    16801 aaaaaggatt ttatctccac aaaacattta ctatttgtta caatatacct aattttaatc
    16861 tcatatcaac atttaatgaa gatataacct ttttcaaata ttgtaaagac tccttaaaaa
    16921 tattagaaaa agattctgca aatctctcaa catctccttt ttttaaatac ctaagtatct
    16981 caaaacatac atcaaaacgt gttttcaaaa tttcattata ttcttcatga aaaaatctct
    17041 ctaaatagat tccaaatatc atatattgtt ttaaatgcaa aaatgtttcc tgtaatacat
    17101 aaatttgtgt ataatctact atcttacaaa gtaaaacaaa atctggataa accttacact
    17161 cttcacaatt attttgtaag taccttaaat gagtttctat tttatctaca gctatcaaat
    17221 ccattttatt tcctagtaaa agtactacat cctcaagagt aatcgtaaca aactccatag
    17281 catccaaaag caaactcaac cttttagctc cttcttctgt atttatataa tcatcatcat
    17341 attcagaaaa aagtgttaca tatgttccct tgccattaat tgttttagca attcccaatt
    17401 catttagctc attataggca cttctaactg ttggaagaga tacattatat ctattaatta
    17461 tcgaagtaat tgatggtaga caatctccta ttttaatatt gccttcaaaa atttgacaaa
    17521 ttacatctga aacaattaag tcatataaat aacatttttc caacgttaca gaattaaaac
    17581 tacttgtatc tatactttgt ggagcacgat tttctaccat tttaagtatg gattctctac
    17641 aagctttata catatatgtt aatagttttt taaattcaat tagattcccg tccaatccat
    17701 ataagtaagt ttttcttacc tgctctatgt atttattacg aaaaaagtct atacaacaat
    17761 tatccaagtt atccaagtta tcgaaattat aggccaattg tgaaataatg acatcatgct
    17821 gaataatctc acaaaaatgg tgaatcagga aattatttgt tttacttatt agtttattta
    17881 tatattttag cctttgttct ttaaagacta aataattaga actatttttt tccatacaat
    17941 cgataatctc gtttaattct tcaaagtctt tagatgtaaa tcttttaata ttgtacatag
    18001 caatagaagg aaatattaaa ctaaaaatct tatatatttc tgatatttgt aaaatcttct
    18061 catataataa gtcagattct attgattgtt tactcgtact ctggattaaa actggtctag
    18121 aaccagcttt tgtctctata aagccctttt ctgagagcat ttttattaca gtttttatag
    18181 tattttttga taccatatat tcttctgaca tgctttttat agaatcaagc ctatctccaa
    18241 tagtaatttt accagtataa atttgttgaa ttatatgctc aaaaataatt aaatattgtg
    18301 gttttctctt catatttttc ctcttcgata aattagattt attgtttttt gtaaggtata
    18361 tttactttta tttaataggg caaaatagtt gcttattttt tcctcataat ctataattaa
    18421 tataaaccat ttatatatat ggtctaagtt ttataatatt gtaatgcagt aaaatagcat
    18481 attgtagcta tactacagca aattaacata ccattgtagt atattaattg gaataatttt
    18541 aagtacttca aaattccagc aaaacatata tgtgtttttg atattatgta tattcgttaa
    18601 tagaatagct atacttgttt tacataataa attatatgat acttgctata tgtaattact
    18661 atatttaata cacataacta ttatactttc catacataat tactatactt ggacacatag
    18721 ttatcataca tactgtatat taagatataa tactttttaa attttatata acacagacac
    18781 atgcaataaa aaagaaggta tccataataa gctctttgca tgtacctaaa taaaaactgt
    18841 aaaatagaat atataaaatc taatctattt taagtaaata caatttcact ttaaaagagg
    18901 atgtactatg aaataccata tatttttaat cataactact atattaataa tcgaactatg
    18961 taacatttac atatgcaaaa tagcatcttt tggaaacaaa aatataacta tacataagaa
    19021 ttacaaatat atttttttaa taaaaccatt aatcttcttg ataataatat tcacaaaatt
    19081 accattacca ctatattata tattgtttta catagtaagt cataaattgc tcttaagcag
    19141 aaaaagttct actaacaacc attttattcc caatatggca gtaataagtt tttgtatttt
    19201 acaccttatt actgtaagta caatatcact tgttaaaaat acaagtccag atataatatt
    19261 tgcaaatatg acctataggt taattagtat tttaatagct tctattttag attttatctt
    19321 atggtactct atgaataaaa taaaagagca tatttatata ataactcaaa atcaaataga
    19381 gttcagtcta tttttaaaat ttatctggtt cactttagga tatatattat ttgatagtat
    19441 acaaattaca tttgctccac caagttctct aacttcctac tttatattgg gaagtaacat
    19501 attattaatc ttacaactaa ttatattcat caatcatata tattccattg aaaaaaatat
    19561 ttatttagaa aaagaacatc atagactaaa aatgataaaa caagaacaat tactaaaagt
    19621 aaatttatta aagaaaaaag ctaacattga tgaattaaca tcagcatata atcgaaaatt
    19681 tgcttttgaa aaaatacagc attacattga taacaattta ttattttcat tgatatatat
    19741 cgatttggat aaattaaaga cgataaatga tacatatgga catttagctg gggataacta
    19801 tattattaac ttctcaagta tagttattga aaacttagga atagatgaca tatttgctag
    19861 aataggagga gatgagttta tagttattat gcctaaatct aatgaaaaca ccacaaaaga
    19921 atttatagag aaaataagta aaattatgga taatacgata tcttttagct atggtattgt
    19981 agaagttcct agcgaaaaca aaatgactgt agaagaaatt attaatattg ctgatattag
    20041 aatgtacact aataaacaaa ataatcataa aaggaacaat aactaaaatg aatatttaca
    20101 tgagcttact tgtaatctta ctatgccttt tatcttattc tatctatcat tataattttt
    20161 ttaaatatct ggacataatg attaataact ctaaaaataa atacaaagta tatattgtat
    20221 attttctttt taattattta atttttatta tttgtactta tttaaggtta catctagtta
    20281 taaattggac aatttttatg ttaattttat ttatgcaaat taaagtaact tacaaacttt
    20341 ccacaataaa aaaccttttt tattcgttaa actgctccat cattggttta gcaataaata
    20401 tattttttag gtctttaatg tcaatagtgt taaatatgcc agcatattta tttgatagta
    20461 attctattac aaatatttac agagtatttt ctatattgct tagttttata gttacaggat
    20521 tatatttcag ttataaaaat cataaaaata ataagattaa ctttgaggca gttttagagg
    20581 acaaaaaaaa cttaattttc ttattgagcc ttatgtttgg aatgtacttg tatctatgtt
    20641 tgagtttgtc aatatactat actgttggaa atgtattgat tttaaaatta tatggaatca
    20701 agtctgccat aatagttttg gtaggtaact atattgcaga aagatatagc tttagaatta
    20761 ctcaaataaa aggttatgat attaaaaatc aaatagaata tgtagaaagt gtaaagacag
    20821 agtatgaaat taataaattg aatgatattg tatatacaga tttactgaca ggcttctaca
    20881 atagaccttt tgtaaatcaa aaactatcag agtggacatc aaatcactac aaatttacct
    20941 tatgttttac tgatttaaat agcttaaaac ctgtaaatga taaatttgga caccaatttg
    21001 gtgataaata catatccact actgctcaaa taataaaaaa acttataaat gtagaaaatt
    21061 ccttactatt tagatatggt ggagatgaat ttttattcct tttacagaat acaagttgtg
    21121 tagaagcaga aaaaataatg attaatataa attatgaatt atcaaaatta agtaatactg
    21181 acgagtatcc ttatgctctt tccataagct atggattagt tgagtgggat ggaatatccg
    21241 atattgaaac tttaatatca aaggcagatt ctttgatgta tgaaaataag cttaaaaata
    21301 aatctacttt aaactagcta gttaagatat tctacaaaat atatgttata agagagtact
    21361 aagaatgtca aaatatatag attttgcaaa tattgaatac agtttactaa tgaatgcact
    21421 ggatgtaagt gttagtaaac acctattaga tgaacacttt actgttgttt gggctaatga
    21481 ccgttattat gaaatgttcg gctataccta gctaaaaagt taaaaatgac cactgtagcc
    21541 gagggaatag agaccagttt tcaaaaatat ttcttgcaag aaatagactg tgatatgtta
    21601 caaggatacg tgttctctag acctttacca ataaaagact ttgaaaaact tatgtttcaa
    21661 aactcctcca attaacaata taaaattgct tattataagt gatattattg tatcaacaaa
    21721 taaaggaatt gtctcaaaat tgattttttc taatcaaatt tttattttga gacattctca
    21781 tttttttgca taagaaaata cccaccaagc tacggttttt cttaccgctg ttcggtgggt
    21841 attagtagta ttatgaaatc tgaaaacttt aagtattact acttcctcta gcgcaatcac
    21901 aaaggtcgaa agcttcaaag cgaaaatagg ctttttactc atcaaacgtc accgtacctg
    21961 ccaacccgtc caccgttatc atttgtccgc tcttaatagc tcgtgtggca atgtgtgtag
    22021 ccataacggc tgggatgcca tattcacgtg cgacaatgct tgaatggcta agaggaccac
    22081 caatgtccgt tacaatcgca cttgcagatg aaaataatgg tgtccatgct ggagttgtgg
    22141 taactgcaac caaaacactt ccaggttgaa agctttcaaa atctgctgga ctattcagta
    22201 cacaagctgg agccgtcaca acaccagtac tggtaccaat gcccgtcaac acaattttcc
    22261 catctttctg cttctgttgt gcttgtgata tagttttttt gtttttctct ggcaacttgg
    22321 atggtgacac ataacccatg tattttttaa gttcagcttt tcgaacaggt attatcccgt
    22381 tcatatcaga tagagacttg tttttatcca actgctctat aagtacctcc aattccgatt
    22441 ttgtgagcca ataaatatca tctaaatgtg aaatagctcc tcctcgtatg aatcgttctg
    22501 agatttcctg aaacatacaa cgaatcagag gatgtcccat tcccatcaaa taaatagcat
    22561 tttcacgcat aggagaggtt tcctgtgccc aatggagcaa cttaaaaaat agttttttac
    22621 gcaatccacc tatgtgttgt aaaatctctt cttctgcatg ttttctacgc ttttcaaacg
    22681 tggtctggcg taaaaaagga ctttcccctt ttccttccac aaatgttttt acggattcaa
    22741 aagttggtgt aagtgtttcc tgcggtgtgg aatgcgcaaa atcaaactca taagcggtac
    22801 gaccaaactc tttaaagtac ttattgattc gatttttcca ttctatccat acttcctgtg
    22861 aaactccaac aggcacaact gaagacatga aatcttctgc tatctttatt gcaggactgt
    22921 tttgcagata aaggttgatg ctgttatttt gctttaccca ttctgaaata ccccacaact
    22981 ccttttccga ttgcagaaca atcgtatcaa acccaagcag gaaaacggaa gtatccgtta
    23041 taccagcacg tcgaactgct ccttgaaata attttgtaaa taatgtttca ctgatagaag
    23101 cagcaggcaa tgtaagctga atccttgtga aataaataca tgcggcataa aatattgtct
    23161 gaataccctc cataatttga tgggcgttca tagtatgcag gggcttttct tcccattgtt
    23221 taatagcatc ctcatatcct tttcgtgccg tttcccagcg tgcaacgctg ttcataagtg
    23281 tcctacgtaa agagcgtggg gaaagggatt tgatagcaat caaaagtggc tttgatttag
    23341 cagaaagata aacatatcca ttaataaccg tatatgcccc gttttttggt aataattttt
    23401 tcgcactttt accaaacata tctatccata aaagctctga tgcacagttt acgatttcaa
    23461 gaccaagcgt ggcgaacaaa ggtgtaacag gatttggcaa gtgttctgcc aaacttccct
    23521 ttgtgtatac aacatcctgt tctggcaata cccattctgg tggcagaaca gtaattggac
    23581 gagcctgaac aatgtacaat ttatcttttt ccagtgccca ctctacatcc ataggcattt
    23641 gataatactt ctcaattttc tttccaagct gtatcagttg cattacctga ttacgagtaa
    23701 gagcatattt ttttctcaac ctttcaggaa ccatggtttc ttctgttcct tctgaagtac
    23761 gaaccgtcat aatctcttta tttgccactt catacgatat aattcgttcg gagtccttat
    23821 ccactacaat tgtatcgggt gtaactaagc tagaaaccac cgcttcacca agcccccatg
    23881 cagcgttaat aatcatttcg ctacgtctac cattgattgg gtttaacgta aacataatac
    23941 cagatgaatc ggaaaatgca agcttttgta ctacaacagc aagtgcgaca atctcgtgct
    24001 ttatattatt cttcacacga taagcaatag cacgagctgt ccataaggaa gcccagcatc
    24061 tctttacagc gtcaataact ttatcttcac cttgtatgtt aagataagtt tcctgctgac
    24121 ctgcaaaaga agcgtcaggt aaatcttcag cagtcgcaga cgaacggaca gccaccgata
    24181 tgttccctaa tccggcataa gccgttttaa ttgcatccga cacttcctgt ggcatttctc
    24241 cattatggaa aagctcccct attttcttag atacctcttc aagttggctg gtattattgg
    24301 aatcaatacc atctagcagt ttattaattc gagactgaat atggttcgtc tcaacaaaaa
    24361 tctggtatga agcagtcgta acatgaaaac cgtctggcac agggatgcct gctgtcaata
    24421 gttttgataa agacatccct tttccaccaa caatttcaat ggttgcttgt ttatgttcca
    24481 gtggcaagac ataataaatc ataatcattc acctccatca ttcataattc cgtgcagaaa
    24541 tatattcatt gtttcatcca acattttttc cgaactatcc gatggtcgtg acgtgtagct
    24601 gattgataac atggagttaa ttaacaaacg tgtcacaaga gcggtatccg ttttgcgaaa
    24661 gatgcctgtg gtcacaccat tatcaattac cgattttata atatcttgat atgcataacg
    24721 agcatcttta agtctctttc gatactcttc ttctaaataa tcagattctg tatttaacca
    24781 catcagtaca cttctatact gctctggaaa tctaagatga ttaagcatga tttttctaag
    24841 gcactgttgt ggtgaaggtt caccatcaat aatcctatga acttgttgga tagttttttc
    24901 aatttctttc tcaactgcat atacaacaat ctcatctttc gttttgaaaa aatcgtatag
    24961 acttgacttt cccatgttgg ctaaaactgc aatttctctc attgatgttt tttggaatcc
    25021 attttcagcc atgagactca aagcaacagc aactattttt tctcggcgtt ctgcttgttg
    25081 ttcgggtgta agcacaattc cttttggcat agggcgatac ctccttttag cgaccactgg
    25141 tcgcttcttt tttatttatc atacagcgac caacggtcac ttgtcaaggt taattttttt
    25201 cattgtatat ggtactcgag ataaaaatgc tcattttaga aattgctcta tttaagtaga
    25261 aataggcttc atcattagaa aacaagacta taaatttgag atatttatca tgttcaaatt
    25321 tcatcaatat caaagtttaa gatattaata aaaaaagaat tactaagaaa taacatataa
    25381 agattcaaaa aaggagttga acttaaaatt caattacaaa aaatcaaatt taagacaact
    25441 cctttattct ttatctctac tattctttat ctctatttat ttattacaac tccctaacat
    25501 ttaccactac tgccttaggt ctagtcatag cctcgattga atacttaaca ccttgagttc
    25561 ccataccaga tgcctttaca cctaaaaatg ggaagtggtc tggacctctt tcagtcttat
    25621 tatttatttg aacagtacca acttcaagtt tatcagctat ataaaatgcc ttatcaatat
    25681 cacttgtaaa tactgatgat tgaagcccat actctgattg attagcaatt tcaattgctt
    25741 gatttatatc tttaactctt ataattggaa gtactggacc aaatggttct tcccaagcaa
    25801 ttttcatatc aacatttaca ttatctaaca atgttggata gaataaatta ttttttctaa
    25861 cattgcctgt tattaacttt gctcctttat gtaatgcatc atcaaccaac ccttgaacaa
    25921 aatcagttgc tttattatct ataagaggag tgataactac ttcatccatt ggatttccaa
    25981 ttgtcaactt ctctaccaat ggctttattt ttccgactaa tttatccgcc acactctctt
    26041 gtactaaaat tctctttact gccgtacatc tttgtcctga atatgaatac gctccagata
    26101 ctatattctt agctgcaaaa tctaagtctg catcttctaa tactatagcc gcatcttttc
    26161 caccaagctc caataataat ggtaccattc cagatatttt agatatatgc tgaccaactt
    26221 cagtactacc agtaaagtta ataaaattaa ttcctttatg cgttacaaca taatctccta
    26281 tctcactacc cctacctgta atagtattaa gtgctccatc tggtatccca gcttttctca
    26341 taatttctac cacatgaagt gcgctaatag ccccttgtgt agcaggtttt aatacgactg
    26401 catttccacc aataagtgct ggagcaatct ttgacattga taaatttaca ggataattaa
    26461 aaggagatat agctaaaaca gtacctaatg gaactcttga aacataagac atcttatttc
    26521 ttgttccacc agggaaatta tctccactaa tggcttctcc ctccatattt tttcccacat
    26581 cagctgtgta tcttaaaaaa tctgctgttc tctcaacttc tgcccttgca gattttatgt
    26641 ctttggctat ttcaagtacc agtatattag ctatctcatc tatattttct aacaataaat
    26701 cagcagcctt atgaaatata ttggctctct tgtatacagg catttcagcc catactttta
    26761 tactctcttt tgtgtttttt ataacctcat ctacctcatg ttttgtcata gattgtactt
    26821 tcccaacaag agaattatct attggtgagt aaatttctat tggctttctc gaattagatt
    26881 ctacccattt tccatttatt aaatttttat atacattttc ttttgtttta agttcattaa
    26941 acatattttt attcctctct ctgatataac tttgtgtatt taaattatag ccatttattc
    27001 gttatgtaaa catttctttt tttcataaac gtttacctat aaaaaaattt taagttaacg
    27061 tttttctaca ttcttctatt ttaataacat actcgctcca aatctatata ggtcacactt
    27121 taatatcaat ataccaatat accaatatac caatatacca atataaatat tataaacata
    27181 aatcacttga caaatttata agtagacaat attatatatc tatgacttaa aatattttta
    27241 aagtcataga tatcatatat agatagaaag gattgataaa aatggctaaa agttttacag
    27301 aaatagaaaa agacaatata agaaaaagac taatttcaga atgtgaaatc aactggtcta
    27361 aatatggata caaaaaaact aatattgatg aactttgttc aaaatcagga attgcaaagg
    27421 gttcattcta cacattcttt gattcaaaag aaaagttatt ttttgaagta ttaaatggaa
    27481 tccaaaacag acttatatca tcagtagatg aaattttaag taacatgcct ccaaaagaag
    27541 gctttgcaaa atccttaaaa atgttatatc gattatatga taaaaatcca tttttatatt
    27601 caccaaataa tcctgatttc atcagcctaa taaataaact acctcaagat atgtttttac
    27661 aacttgagtc caataacata caaagttttt acgacttaat tgagagacac aatctcaagt
    27721 tgaagataga aaaagaaaaa gtttttggtg tttgtaatgc tctactatca agtctgttgg
    27781 taaaagaaaa tattgaatat aactatattg aagtgtttga ctttatggtg gataatcttg
    27841 tagaacacat acttgaataa caatttaaaa taatttttct aagtattttt ttatactaaa
    27901 taggattaat atgattgaat taatgcaaaa aataaacaat ataatttata aaataaatga
    27961 taaactaaat atcacacaaa acttatagac cctagagcaa acccattcca ctctactcta
    28021 agccatctat aatagtttgt atatttctaa taatattaga tattaaagta agaaaaaaat
    28081 tccttataat aattgctatt atatcaatta ttgtaaatgt tttaataatc ttagataggt
    28141 aggtacatat atggtaaaat cctcgaacac ttttaataaa aacttcaact tgatgatatt
    28201 aggtcaaata atctcattgt ttggtgcatc aatacttaaa tttgctttat ctttatacat
    28261 acttgatata actggtaaag cagaaatatt tgctactata ctagcagtat cttcaatccc
    28321 aattatagta ttctccccta ttggtggagc tattgcagat atattcaaca gaagaaactt
    28381 aatggttatt tttgattttt caagtagtct tacagtacta atcttagcag tattcttatt
    28441 caacaataat ggttcaatat tacttgtagg aattattatg accatattat cagtcataag
    28501 cacaatgtat caaccaactg ttcagtcaag tacacccctt ttagttgata atgagcattt
    28561 aatgaatgca aatggtattg tagctggagt tgcatctctt acaaatattg caggacctgt
    28621 attaggaggt gtcttgtatg gtgtgattgg aattaatgca attatagtta tcagttgtgt
    28681 aagtttcttt ctatctgcaa ttatggagat atttatacag attcctttta tcaaacaaga
    28741 gcaaaacagc aacattataa aaactatatt tactgatata aaggatggta ttgttcatat
    28801 atgtaaagaa aatagattta tactaaaaat acttttttta gctatagcaa taaacttatt
    28861 tttaagctct atgttaatag ttggtatccc ctatatagta aaaatcacta tgggagctag
    28921 taacttctta tatggtctag cagaaggagc aatttctttt agttcactgg tagctgctgt
    28981 tagtattggt attttctcaa aacatctaaa aatcactaat ttgcatattt tctttattat
    29041 atgtgcagtt atgttcatac caatggcggt ttcagtatat ccatttatat taaacacagg
    29101 atttccagtt ccatttttaa tctttatagt atcatctatg ctaatatttt ttacaacgac
    29161 tcttatctca atatatgtta taacagtcac acaattaaaa actccaaatg aactcttagg
    29221 aaaagtaatg tcaattcttt ttgcaggaac agcaattgca atgccccttg gtcaggttat
    29281 gtatggtaaa ctttttgatt tattatcaga tagagtgtac atcattatac taggagttgg
    29341 atttattaca ttacttatag catttgtatc aaagataaca ttgaggaacg aaaatcttta
    29401 gatacaaaga atttagatat aaagatttaa ttttcactaa tttctgaatt taaatgcaaa
    29461 attgtgtatc agtatgttga cgttttagaa attgattgat ataatcaatg gaaaataaac
    29521 tttataaaaa ttcaaaatat tcagctagag gagtgataaa aatgagttac atgccaactt
    29581 tagaacaagc atgggaaata ttaagaaaat acaataagga agaatttcat ataagacatg
    29641 ctcaaattgt atctggagtt atgagatact atgcaaagga gtacgaccct gaaagagtag
    29701 aattttggga aatagttgga cttttacatg atttagattt tgaaatgtat cctgatgaac
    29761 attgcgttaa acaaagagaa ttaatgacag agcttgattt agataaatca ataatcgatt
    29821 ctacaataag tcatggatat ggattaactg gttcagatgt taaaccagag caatttatgg
    29881 agaaagtatt atttgctgtg gatgaactta ctggtttaat tggtgctgct gcaataatgc
    29941 gtccttcaaa gagcgtttct gatttagaat taaaatctgt taagaagaaa tttaaagata
    30001 aatcatttgc tgctggctgt tctcgagacg ttataagaag tggtgcagaa atgcttggat
    30061 gggaacttga taagcttatc caaacaacta tagaagctat gagaagcttg attccagaga
    30121 tggcaatata gctcctccat acatatacca tagaagttac atctttaaag agcatttctc
    30181 tttttgatgc aacttctttt tatattttgt agaataaaaa gtttaatatt ttaaactcac
    30241 tatataatct ataataaata ctataaataa tataatgtat aatagttata aactttctaa
    30301 ccttaaaagt ttctaataat caataaacaa ttctaatata caaatgtcat tatatgattt
    30361 aattatatat cttcaattta tatattaaaa taaatatata tatattaaat tcttatacac
    30421 caaattttta cattaaactt ctatgcacca catttataca tattaaattc ttatatatta
    30481 aattt
//
LOCUS       DAEPUT010000045        29743 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.046, whole genome shotgun sequence.
ACCESSION   DAEPUT010000045 DAEPUT010000000
VERSION     DAEPUT010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29743
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.046"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(693..1286)
                     /locus_tag="KRL22_002213"
     CDS             complement(693..1286)
                     /locus_tag="KRL22_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1272702.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
     gene            2135..2784
                     /locus_tag="KRL22_002214"
                     /pseudo
     CDS             2135..2784
                     /locus_tag="KRL22_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
     gene            3009..3680
                     /locus_tag="KRL22_002215"
     CDS             3009..3680
                     /locus_tag="KRL22_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1272703.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            3677..4807
                     /locus_tag="KRL22_002216"
     CDS             3677..4807
                     /locus_tag="KRL22_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1272704.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            5239..6084
                     /locus_tag="KRL22_002217"
     CDS             5239..6084
                     /locus_tag="KRL22_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272705.1"
                     /translation="MIKVRELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            6084..7112
                     /locus_tag="KRL22_002218"
     CDS             6084..7112
                     /locus_tag="KRL22_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272706.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            7115..8128
                     /locus_tag="KRL22_002219"
     CDS             7115..8128
                     /locus_tag="KRL22_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272707.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKYSILKGFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(8645..9895)
                     /gene="cme"
                     /locus_tag="KRL22_002220"
     CDS             complement(8645..9895)
                     /gene="cme"
                     /locus_tag="KRL22_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HBH1272708.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(9981..10727)
                     /locus_tag="KRL22_002221"
     CDS             complement(9981..10727)
                     /locus_tag="KRL22_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1272709.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(10880..11902)
                     /locus_tag="KRL22_002222"
     CDS             complement(10880..11902)
                     /locus_tag="KRL22_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBH1272710.1"
                     /translation="MNKNNCLDLIFEKVNPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDIFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKNWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(11902..14322)
                     /locus_tag="KRL22_002223"
     CDS             complement(11902..14322)
                     /locus_tag="KRL22_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1272711.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQTNSSESEIGDEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHNILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(14408..15328)
                     /locus_tag="KRL22_002224"
     CDS             complement(14408..15328)
                     /locus_tag="KRL22_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1272712.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            complement(15927..17144)
                     /locus_tag="KRL22_002225"
     CDS             complement(15927..17144)
                     /locus_tag="KRL22_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1272713.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(17226..17429)
                     /locus_tag="KRL22_002226"
     CDS             complement(17226..17429)
                     /locus_tag="KRL22_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1272714.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            complement(17890..18120)
                     /locus_tag="KRL22_002227"
     CDS             complement(17890..18120)
                     /locus_tag="KRL22_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1272715.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            complement(18117..18539)
                     /locus_tag="KRL22_002228"
     CDS             complement(18117..18539)
                     /locus_tag="KRL22_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1272716.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            19044..19397
                     /locus_tag="KRL22_002229"
     CDS             19044..19397
                     /locus_tag="KRL22_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1272717.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            complement(19457..19624)
                     /locus_tag="KRL22_002230"
     CDS             complement(19457..19624)
                     /locus_tag="KRL22_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBH1272718.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(19743..21662)
                     /gene="tet(M)"
                     /locus_tag="KRL22_002231"
     CDS             complement(19743..21662)
                     /gene="tet(M)"
                     /locus_tag="KRL22_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBH1272719.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            complement(21914..22846)
                     /locus_tag="KRL22_002232"
     CDS             complement(21914..22846)
                     /locus_tag="KRL22_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1272720.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            complement(22843..23844)
                     /locus_tag="KRL22_002233"
     CDS             complement(22843..23844)
                     /locus_tag="KRL22_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH1272721.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            complement(23841..26018)
                     /locus_tag="KRL22_002234"
     CDS             complement(23841..26018)
                     /locus_tag="KRL22_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1272722.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            complement(26021..28468)
                     /locus_tag="KRL22_002235"
     CDS             complement(26021..28468)
                     /locus_tag="KRL22_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1272723.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            complement(28452..28958)
                     /locus_tag="KRL22_002236"
     CDS             complement(28452..28958)
                     /locus_tag="KRL22_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1272724.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            complement(28933..29430)
                     /locus_tag="KRL22_002237"
     CDS             complement(28933..29430)
                     /locus_tag="KRL22_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1272725.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            complement(29547..>29743)
                     /locus_tag="KRL22_002238"
     CDS             complement(29547..>29743)
                     /locus_tag="KRL22_002238"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272726.1"
                     /translation="WFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLV
                     FNAAGVKDILLELFNRIIGA"
BASE COUNT         9636 a         4917 c         4920 g        10270 t
ORIGIN      
        1 gaaatataga aaattaattt aaagaagtat aataaactaa tttaggaagt atagaaagct
       61 aatctaaaga agtataataa actaatttag gaagtataga aaattaatct aaagaagtat
      121 aataaactaa tttaagaaat atagaaaatt aatttaaaga aatacaatac attaattttt
      181 aagtaacatt aaattaatgt aagtaaaata atgttcatat gaagatttaa aggtgcattt
      241 tctgaagcta agtatatgtt gtagagtgtt atgtctctct atccagtgaa gtttaatagc
      301 tcaagaaaat gcactattta tgatgattat tttgttttat ttccaatttt ggaaataact
      361 attctaatta aatctaaaat tataccataa ataagaaaag aaagtataga tgctatgtac
      421 caataaatcg aaattgaccc tgtaattgtt ctacatggga tttgcatacc tgaatccata
      481 aaacaaaaaa actatcaact ctggaaataa tagacaaaat aggatttaaa cctattagaa
      541 taatactttt tgagtcttga ccaatttgat gcatataaat ctcaaataat gcaattaaaa
      601 aaaaccaaac tgtaaaagat ttaataattt ttttcatcaa aatacttcac ataatataaa
      661 ttctgtttgc actatttgct tactacaact atttatctcc attcagtcac atcacttaat
      721 tgtaatctag gtcttcttga tggttcttca tcaggataac ccaaagatat tgctgccact
      781 aattgactat ctgtatttaa ccattcacat aattcacgat atgcaaagta tacatcacaa
      841 atccaaagac tacctagacc taattccaca gctgtaagcg acatattctg aattgcagct
      901 ccaattgatt gcatgtttgc catttcatag aatcgttctt caggggatag cttttctaaa
      961 ggtgatttac ctaatatatt taaaataaaa attgttactg gagcttgttt catgatttca
     1021 actgtgtaat ttgcaccagc gatatgttga cgacttcctg gaagaagccc attatcatta
     1081 atttcatttt gaataccttt gctcatggct ttaagcatag attctttttc cttttcagtg
     1141 atgacaacaa aacgccatgg ttgcctgttt ttagatgaag gtgcatttat tccagcttca
     1201 attattttct ctatagtttc atgtgaaatg ctttgatttt tatattttct gatacttcgt
     1261 ctttttgata tagaatcact tatcatttta agtaacctcc gtttattttt tggaaaaatc
     1321 tatttaattt ttattttcta ttttaattat tttagcatta atcagaaaaa aagtcattga
     1381 ttttagtata caattattaa tgattatatt aagaattgta tcaaaaagta tgtgattata
     1441 ctaagggatt atattaaaca ttatatttaa aattgtatga aaggttgtat ttaatattat
     1501 attgagagat atatatatta ggatttatat atattcagat ttattattat attgagcctt
     1561 atattaaatt aaggactata atttgaaaat aagctataaa aacttaatat tgttttgttc
     1621 agagaaaaaa aaaatacttt aggtgatttt tattaaaaat taagagtgat aaaattatat
     1681 actttataaa tgtaaatatg acgaataaaa atgataaata taataatata tatatttaca
     1741 ttaggagttt tctatactat aattatttaa aactaaatat aaatgttgga attatttagg
     1801 acttgaaatt gtctaaaaat aaatataagt gatgaagagg tgatgtgatg agattagata
     1861 tggatagtat gttatatgta ctaatttata tgacattatt ggtatctatc attggaagta
     1921 tattttattt ttgtaaaaac ctcttaaatc ataaaattaa gtatgtttta ataagagaca
     1981 tatttgtaaa tagaattaca tattctgaag aacggttgcc taaacagtat atagtttttc
     2041 agaaatatga tatttggagg tattgtagtt tgttttaatt tgaaatgaat ctattataaa
     2101 ttctaaagtt taaaaataaa aaggagagaa taaaatggat ttcatttcaa gtatattgca
     2161 aggattatta agtatattat ttaattttac aggtgatttt ggaatttcta ttgtacttat
     2221 aactttaatc gttaaattag tacttatgcc actatcatta aaacaaagat tttctgtaaa
     2281 aaacagcaag aattagctga aaaaatggaa catataaaag aaaagtataa gaatgatact
     2341 aaagaattgg aaaagcaaat acaagtaagt tctgtagaaa gtatgaagag tatgctggga
     2401 tgtcttatag ttttggttca aatgccagta gtatatgctt tatatcatgt atgtttagat
     2461 atgacaaagg aatttacaac aattataatt ccatggattg ctaatttagg tacatttgat
     2521 aatttgttta tattaccttg tatatataca ttaattatgt tagcttcaaa tttagtgaat
     2581 tatataccat atttaaaaat aaattctcaa gtaaagttta acaaacaaat ggctgtggtg
     2641 actaccataa caagtcttat actaactgtt agaactccag tagccatagg tctgtacttt
     2701 ataacaagtg caatttattc attaattgaa gatatttgtt ttagaatata ttttaatcga
     2761 aaaaatagaa tagtgacaaa ataatataat tattattaga aatattttag cctgctaaca
     2821 tagaaaaagt tagtaggcta tttttatcta tgatatcaat tccattaaga atagtctaaa
     2881 aaatactatc aaaatgctat aaaaaatatt ataaaaatac tatcaaaata ctataaaaaa
     2941 atagttgaaa aataaataaa ttaatataaa ctaaaataaa gcctacaaaa aagaggtgat
     3001 aaatagaaat ggctaaaata ctaattgtag aagatgaaaa aaggatgcaa agtattattg
     3061 tagaatatat gcaaaaggga ggatatactt gtataactgc tgatgatgga gtcgaggcac
     3121 ttacaatatt aaagagcaac aatatagatt taatgatatt ggatattatg atgccgtatt
     3181 tagatggatt ttcagtgtgt agagtttcac gtgaaatgac taatatacct attattatat
     3241 tgacagctaa aggtgaagag gaggacaaat taaagggtta tgaatatggc gcagatgatt
     3301 atataacaaa accatttagc cccaaagtac ttttagcaaa agttaatgcc ttgttacgta
     3361 gatacactac tgatattccc aaaaattcat tgagtttagg aaagattttt attatggtag
     3421 catcaaggca agtgtatgta gaagataaat tgattgattt aacatataaa gaatttgaat
     3481 tattgcgttt atttatggaa aaccctaatc aagttttttc cagagagaaa cttttaaatt
     3541 gtatatgggg atatgatttt gaaggaaaca cacgaactgt agatacacat ataaaaacct
     3601 tacgcaaaaa gcttggtagt gaaggacacc atatagttac attaattcgt tcaggatata
     3661 agtttgaggt taaggaatga atagtttaag aaagattata gaaaaactga aaaatgtaga
     3721 tatttcaaat tggattaaac aaaattttgg actatattca gttagaaaaa aagtgttttt
     3781 actttctaaa ttatcaggag cgttaattat attattttat ctggttgttg aagaattttc
     3841 gataaactct aaatttgaat tttggatttg gtttataata ctggttatat ttattatgag
     3901 tattgatttc ttattgggaa aatttatttc agaaccaatc acatctataa ataaatctgc
     3961 aaaaagtatg tcccaacttg atttttctaa tccatgtact gtaaatacta atgatgaatt
     4021 tggagaactt tctaggagcc tgaatacaat gtctacaaat ctacaacagg cattatcaga
     4081 cctagaaagt gcaaatattc aacttgaaaa ggatgtaaat aaggaaagaa tgctattgga
     4141 acaaagaaag gagttggtag atacaatttc acatgaaatg aagactccac ttggcattat
     4201 acgtgcgtat acagaggggc ttatggatga agttgatgaa gaaaaaaaga aaaattatat
     4261 gaatgttata atagaagaaa ctgatagaat gaacaatatg attgtatcat tattagactt
     4321 atctgcattg gaagcaggag tttctaaact taacccagag cgttttgatt ttatagagtt
     4381 tgttgaaact gtggcaggtc gtcttttaat tgatatacca gatgccaatt tttattttac
     4441 atatgatttg ccagagtatg aagtttttgt agtggcagat aaaatgagaa tggaacaagt
     4501 agtagagaat ctagttatta atgcaaagaa gcatgttgta tataatggta atttagattt
     4561 atcgattaca tgtgaaaatg gcttgctttt atttgaaatt tataatgatg gtaggtttat
     4621 agagcaagat gagatttcaa agatttggtc taagttttat cgtagtgttc aatctcagcg
     4681 tacaggaggt tcaggtctag ggcttgcaat tgtttcacaa atacttacaa tgcaagggtt
     4741 agaatatgga gtgaataatc gtgatagagg agtagagttt tattttatga ttccaattga
     4801 tgaataattt agtattaatt tataaatcat aagtatctga tgtaaaatat ttttatttgt
     4861 atatgtaagc atttaaagag aataaaataa aaaaacttaa tgaaaaaagc ttaatgaaaa
     4921 agtctaataa aaagtttaat aaaaagctta ataaaaagtc ttgttttcct gatgaaaaca
     4981 agatttttta ttaagctttt tattatttca cttcgatttc acaagagaga cactctgatt
     5041 tcaccaaata gaaataaaat aggttaaata aattaaaaaa tagaagcgta attaaataag
     5101 gttacaaggg ggagtactta tgaaatggta tacatggttg actattatat tgataatatt
     5161 gctttctatt ctgcttaaaa ttaaatttat aaaatggtgg gatagacgac aaaaaaatga
     5221 taaaggaggt tatgatagat gataaaagta agagagttaa aattttctta tggaaaagat
     5281 aaacagatat tgcatggact taattttgaa gtaaaagaag gagaaatctt tggattcctt
     5341 ggacctaatg gttcaggaaa atccacaaca cagaaaatct taaatggcgt tttaaaaggc
     5401 tacaatgggc acgtatccat ttttgggaag gaagttaaag catatacaga gtctctatat
     5461 caaaagattg gtgttttatt tgaatttcct tatttatata ccaatttaag tgcaattgat
     5521 aatttagaat atttttcgtc tttttatcct aaaaatcaaa ggagagacat atatgaactc
     5581 ttagatttgt tagagtttaa gaaagagttt ataaataagc ctgtatcatc ctactcaaaa
     5641 ggtatgaagc aacgtattag catggcaaga gcattggtaa gtaatccaaa gttgttattt
     5701 ttagatgagc ctactagtgg acttgaccca tctggagctg tactatttcg taagattatt
     5761 gaagaagaac gaaaaaaagg aacaactatc tttttgacta ctcataatat gctagatgca
     5821 gatttaatgt gtaacaatgt ggcttttatt gcagatggaa agattatggt aatagataaa
     5881 cccaaaaatt taaaaatgaa aaatagcaat aataaagttg aagtggaatt tgtatataat
     5941 ggaaatcgag atattgaaat tgtagatata caagagttag aatctggaat aacttttaaa
     6001 tatgatgaaa tcttaagtgt acattcaaaa gaacctacac tagaagaagt ttttattaaa
     6061 tacacaggaa ggatgttagt gtaatgtatt ctaaattttt taccttagta aaaaaagatt
     6121 tttggatgat gatttatggt aaattttttg tgctgacact tggctctctc atactttatt
     6181 cgtgttatat taattttggt tatgtaaagt ttatggatga agatagttat cacaataatg
     6241 tatatctata taatccagag aatataagca tgagtgcatc tccattaatt aatcaagttt
     6301 cttctatagg tgaattaaaa gcaaaacttg atgaagatac aagtgcagtt tgtattgata
     6361 tgagttccag taagccgaaa gtaattttac atgaaagtat taaaggagtt gacaattata
     6421 gagctgacta tgcattgtca ttattatcat cagaaaaaga ccataatagc aaaatatcag
     6481 acaacaatgc aataattcaa attaatgata aggatacatc tgagataaaa caaagaaaag
     6541 acatgacttg tgagatttta ttctttgaaa ttgtagctat tggattttta gggattgcct
     6601 ctttattatt taaagaaaag cagatgggag taatgcgtat tactggtatt ttacctgtaa
     6661 aaagaagtct ttttatatta tcaaagatat ttgctttttt tatatgtgac ctatgtttta
     6721 cagttctttt agtagtattt aatattggat ttttagaagg aataaaaata cttccacaag
     6781 tattagttca agctagtatt ttatcaatta ttatgtcttt gattggaata ggatgctcaa
     6841 tgttattgag agattttaag caattttctc ttatatatct tgtggttgct gtattcataa
     6901 ctacacctat atttctatct gcaaatacat cttttgaaat agattggatt aaatatcatc
     6961 ccttctatca tgtttatagt cagcttaaaa atgcgttttt catgaatttt tcaaaagaat
     7021 tagtttattt tgtagtgtgt tctttgacaa taatagttct atttttactt gtaaaatata
     7081 tttttaataa agagttggtt agggagggat aatcttgata ggattacgtt accagttaaa
     7141 gagtataaaa aaagataaaa tgtgtataat ttccttcttt ttaccagttg ttatggcgat
     7201 tttaataaat tttatgggaa caattgatat atcttcatta ggagagatac gttttggtat
     7261 agtgaaggat acacttcctg tacaaacaga gcagtggttg aagaagtatg gtatggtaag
     7321 tgtatatgac acaaaaatgc atttaatacg tgaaattaag gatattaaaa cggacacaat
     7381 tggagttgtt agagatggta aagggataaa aactgtgctt tatggaaatg agattaatgc
     7441 tataaaaaat gttggaaaga cattgccaga gatgtttaga ctaaagggtg atttaaaaga
     7501 tgttgaggtt acaatattgc ctaaatatag tattttaaaa gggtttcaaa atgtttttat
     7561 tgctatgatt ttaattactg ctatgtttat gggatgcacc tttaatgcaa tgaatattat
     7621 atcggaaaaa gaagatggaa tatcatttat aaatgaagtt ttgccacaga gtagaagtca
     7681 gtatattata caaaaagtat ttttgggtct tttatgtggg tgtttatctt caatgataac
     7741 tgtatttata tgtttggata tttcaatatt agatatgata atgatgttgt tactcgttgt
     7801 attttcagca tttatttcat cacttatagg tttatttatt ggaaagttgt cagaaggtct
     7861 tatggtagga attgtttata ttaaaatagt aatgatttta tttataggta ctcctttgtt
     7921 aatatatctt ctaggggtta ataccagtgg tatagggaat ttatgctata taatgccttc
     7981 agttgctaca tttaatggta ttatggagat tattaatggt aatgtcatta ttatcaaaga
     8041 tattgtaatt ttggctgtac attgtgtagt atggtttatg atatatatta ttttagataa
     8101 aaaaagaaag ttatctttta gtagataact cagtataatt ataattggga caatttaata
     8161 ggtgatttaa tatactttgt atagtgtaat ttatgtagtg caatttgtat actttaattt
     8221 atgtagtgta atagttagtt ttattttata attattcaat ataatttagt aagaagttca
     8281 gtacaattag agctacttag tggaaaactt aataggtact taaactatat aaatacttta
     8341 ttttcctcca tttgtactat aaatttaatt tatgatataa atggaggtat tattatatga
     8401 tttgataaat ttcatcatta taacctacaa gtaaaggtat tattatataa agttaataaa
     8461 gatagtatca aaatattatt tgctataaag agagggactc aaaataaaga taaacctatt
     8521 tttcaatgtt gaaatgataa aatatatttg atttcatata aaaaattttc ttcataaatt
     8581 aaaaagtcca ttttaagccc cttcattttt aaccagataa atcgagttaa actatttaaa
     8641 tatattactc ggattcattt gacttagata ttccttgctt gtaaaattgt tttgaatagg
     8701 ggatagccaa agcaaaaaat aaaagtataa tccctgctat gattattaaa ttattaatag
     8761 aaattacatc tgccattggt ccgaaaatca tcataccaag aggaataaaa ccagtatata
     8821 taataatagg taagctaaga actctaccta gcatttgtgg tgctacatgc tcttgcaaca
     8881 tagtcatagc tgatgcttga atgattggaa ttgaaaaatt cgtaaaaaac ataaatataa
     8941 aaaattgcca agcttgtgtt acaagaccta gaataattga aaaaatagca taggataata
     9001 ttgctagaaa aaaggtctta tttctatttt taaaaccacc aaaaactcct ataatcaatc
     9061 cacctaaaac catacctaaa aatccaatca tttcaataat agacaggtat atataaccct
     9121 tgccaaatgt tcgttcaata agaagtccta taagaaatcc tgatggaaca caaagaagca
     9181 tgaatgctcc ataagtaaaa agcacttttc taatgaactt atctgaaaaa cagtacttta
     9241 tccctgatac catatctgca aaaaatgaga ctttttcagt ttgttttggt atatcatgtt
     9301 taggaatttt gatgaatatt aataatacaa tagcaataat tgcagtaaat acatcaatta
     9361 aaagaacttg atttatttta ttaccaaatc caagtattgc agcagctaca ataggaacta
     9421 taaattgtac tatagactgt agactactat ttataccatt aaaacgcatt aaatgttctt
     9481 ctggtacaag ttgaggaatc attgcgttta cagcaggtgt ttgtacacca cttcctagtg
     9541 aacgtataac agatattact gatatggcta ttaattcact tgttgtgcca tttgatgaca
     9601 tcataaatag aattagaact aatgtagata tagcaattgt tgaatctgat acaattatga
     9661 gtacctttcg attgtagtag tctgcccata caccagcaaa aaaagaaatt atcatttgag
     9721 gtataaagga gcatacagtt aaaactgtta cccatacacc tgatgatgtc tgaagtgtga
     9781 cataccatat cattgccatt tgtacaagtg atgagccaaa taaggaaata tattgacttg
     9841 ctaaaaaaag aatgactttt ttcttccatg tagaattagt atttttattt tccatcctat
     9901 tcctcctttg atttgtgtgt tgaatttttc ttgctcttaa ggataacaca caaatcaaag
     9961 tctggagtta gagtggaggg ctaggaaaat tgttttttca taatttgaag atgagatttc
    10021 atggtttttg cattatgttc agcttctttc aatgaagtta tcagtttgtc acacactgag
    10081 ataatttcgt catcatcttt tggagtgtca aggacagttt taatattagt attaggatta
    10141 gaagataaag catttaacat tcgtaaaata gctgaaagag aatagtttgc acaacgaagt
    10201 gcgcttataa ttttaagtcg ttttatatct tcatcagtat atacacgata accattttgt
    10261 tttcttttta cttttaacaa accattcatt tcccaatttc ttaaagtatc tattgtaacg
    10321 tttaagtgtt ctgcagtttc ttttctagtt aaaaagagtt tatttgtttc tggagtattt
    10381 ccatttaaaa tctgtgcaac aatagtaagt gcttcctcgg cattagattt ttctatttct
    10441 aattgttgca agtattgatt tacaagacta atagccttat caaagtccct attcgctgat
    10501 gttcttacaa tctcaagggc atcttttctt aatccccttt gtaccacttc aattttcaag
    10561 gctgtacgag caaatctaaa ttgttctata tgaaaatcat taaagatacg ataaccattg
    10621 gtattacgct taggtttagg tattaagttt agttcttcat ataaacgtac tgtattagga
    10681 tgtacaccaa ttaaatctgc tacctctgat gtcgtgtaag tgtccattag tattcaactc
    10741 cttttagata tatagtatta gtcataataa caccaaacaa aagtctggtg ttataatgga
    10801 gggtttggtt atctaagagt aattagttta tgaaagagta attaatttat gaaagagtaa
    10861 ttaatctatg aaagagtaat taatctatta tagaagtaag tatatatttt tcaataaact
    10921 cccatctatc acgaggttta aacactattt tagatggtat ggctattact aagtcatatt
    10981 gtggaataca acaaatagca tttcctccag ttcccattgc tgaataccac aaaacaccat
    11041 cttttttaca tagccaccac agataaccgt attcattact attcatttta accgattctt
    11101 caatccacga tttagatata atacgtttat tattccaaat accatcattt aaatacagaa
    11161 aaccaaatcg caacatatct ctagcactca atgtaagtcc ccagccacct atagaataac
    11221 cctgtctatc ttttgcccaa cccttaagat tttttccaaa gaaatcttca aaaccaaaat
    11281 ctttcatatc ataatctggt ataactttca taccaatagg tttaaataag tattcattag
    11341 caaattcacg agcagatttt ccagtagttt ttgttataat agctgaaagt aggtgcgttc
    11401 cagctgaaga atatttgaaa gtaccaattt cgcctttttg accaagttga ttcaaggtat
    11461 attttatcca atttttttgt ttgcaaagtc tttctaaaga ctcagtcata tttttaaaag
    11521 ggtatggtgc agtcattgta agtaggtgac gtatagttac tgctttttta catatttcag
    11581 aaggactaca agtatattca gggaaaaaat caacaacctt ttggtcaaca tcttttatat
    11641 atcctttatc tattgcaata cctattaagg ctgatataat actttttgta actgatgcaa
    11701 catgaaaaat atcatcagca ttatatccat tatagtactt ttcaaagaca acttttcctt
    11761 ttcttgcaat aattattcca tttatattac tatattgtga gattattaaa ggttcaagtt
    11821 gtgagagctt ttctgaactc ataccaacac ttgaaggatt tactttttca aatattaaat
    11881 ctaagcaatt gtttttattc attaaagata cctccctgtt atagattttg gattttcttt
    11941 tagagttttt ggagaacctt ctgcaattat ataacctcct ttgtcaccac cttctggacc
    12001 aagctcaaca atccagtcac aaacatttaa tacatctata tcatgttcaa caacaattac
    12061 agaatttcca ttttcaacca attcatctaa taattgaatc aacttagaag tatcgtatag
    12121 acttagaccg gtagttggct catccaatac ataaaggata ttaccatttc gttttttacc
    12181 aatttctttt gcaagtttga ttctttggga ttcaccacca cttaaagttg gtgtaggttg
    12241 gcctaatttt atatacccca tacctatttg ttctaataca tttaagtgtg aaacaatatt
    12301 tggaatatcc ttgaagaaat gtacagattc agaaacactc atatttaaaa tattatgtat
    12361 atttttattt ttatatttaa tagataaaga ttcatcatta aatctttttc cctgacattc
    12421 actgcatata tggtctatac ttagattatt tcccaaccag accttttcat atccactacc
    12481 actacattta ggacaagcac ctttggagtt aaatgagaaa tgaccagctg taaatcctcg
    12541 ttctaacgat tctggctgac ctgcaaatag tgtacgtatc ttatcccata taccaatata
    12601 agaagcagga gttgagttca tatttttgcc aataggagat tgggatatct ctgaatatcc
    12661 agaaatatgt ttagtaccaa tcagtctatc tgcaatagtt tcaacaactg cataatcgtc
    12721 ttcatcacct atttcgctct ctgaagaatt tgtttgatta ttgatagtat ggttattaaa
    12781 ttggcttcta agaagaggaa gtagggtgtc tgatataagt gaactcttgc cactacctga
    12841 ttttccagat attccaacca tagcacccaa aggtaatgat acagttacat ttttaagatt
    12901 atttgtattt gcattttgaa tagttataca aggtatttta tcagtatgtg taatgttttt
    12961 attgcttgtt ctattaggca ttggatattt tccagataaa tactgcccag taagtgattt
    13021 gtcggattga agtagacctt ctaaatctcc ttgatatact aattgaccac cttcaacacc
    13081 agcttttgga ccaatatcaa taatatgttc tgccatttta attgtgtttt tatcatgctc
    13141 aactactatg accgtatttc ctaaatcttt aagtttcttt attgatttta agatgtctat
    13201 tttttctgat tcatgcaatc cagctgttgg ttcatcaagc acataaatta atgagtccat
    13261 ctctgaatcg agatgtgaat ttaaaaatag tctttgcatt tccccaccac tcaaagttga
    13321 catttctcgg tataaggata gatgacctaa tcgtgattct attaaatgtt gagttttgga
    13381 taaaatatca tttacaagat ttgtaccaaa tgtgtttaaa ttaccttgat ttattaagag
    13441 tttaaggaaa tcatcaattt ctaaaatcgt catttttcca agttctccaa tatgttttcc
    13501 gtttaaaagt actctacgtg cttcttcacc aattttaaaa ccattgcaat ctgaacaggc
    13561 agtcatagta taaactccat ttaaatcttc gccccttttg taacgattgt gaaatacctt
    13621 tgataaagag gaactttttt taccattttc ataatgacca tagagtactt catttcttat
    13681 ttcttcaggt agttgtaaga attgtatgtc taaataatcg ttgaattttt tagaaaatac
    13741 tctcaaatat cctggtgtaa tctttgctct atctaagact tgttttaggg tgtcatgctt
    13801 atcaaggact aatttttcaa tattaatctc aaaatatgca ccatgtccag agcacttcat
    13861 acacattcca tctgaagagt tgtatgagaa ataacttggt cttaatcgtt cttcctcata
    13921 tccacaatta ttgcaaatta gattatcgct tacaggagta tcacacatag tacacattat
    13981 ttgaccttcc actgaataca atagtgtaag catgttgaga atattggttc ttgtgcctac
    14041 tgttgaacga ggattgctct ggcgaataat attttgttga acagctatag tgggagctaa
    14101 accttgaata ttatcaaact tatcctcact atcaatacct gcaagtatac ctaaagattg
    14161 cagatattgt ttacgccctt cctcaaatac aatgtcaaac ataaggctag acttacctga
    14221 gccactgaca cctgttgcaa caacaagctt atctttgggg atagaaacat ctatattttt
    14281 aagattgtgt atctttgctc cattaatttt tatttctttc attggttcac ctcattttat
    14341 caattttatc aaaccgtaaa atagggatat attaatcctt aatacaagaa tagattaggt
    14401 gaggttatta aaaaggttct ataggtaaat atatatcgac caagtgtcta ttttgagggt
    14461 gattgtgtgg gttgttaaga tatacttcaa aagggaagga ggcacgtagc ttataattac
    14521 catttgatag ccattcatta tacataaaat cccacgcatc actatattca gattttgaaa
    14581 tatcaaaatg tcccacaaga tattttccag aaggtattat catattgcca agattgtcat
    14641 tctctttgac aactatgtta tctggaatgg tcatgcaaat actagtcctt aattgatgct
    14701 cctgtgtaaa ttgtggatta tcatgataaa tggctaatat ttgtgtgttt tcaagtccaa
    14761 gtagattctg ctcacttgca tatgtgaata accgttctaa aagttttggg aaagtactgg
    14821 ttagattacc atatgaacca gtatatctag tgtaaatagt attcatatta tcaagttcta
    14881 gaatttcaat ttcaccttta acctctctag tattcttaca tttaggtttt gatatgcttc
    14941 tattgtactg agaaatttta tatggttctt tgcaattctt gctataattg tttctatatt
    15001 ttatagggct tattttatag taatttttaa atgctctcga gaaaactgct gaatcagtaa
    15061 agccaaagta gtgtgcaata tcagtaacag tcatgtcagt tctatgaata agaaaagcag
    15121 ttgcattttc tagttttagc ctatttacat attgtgccaa agtttctttt tctattgctt
    15181 tgaagattct atgaaagtga aattttgaaa aacctgctat attagaaagt tcatcaagag
    15241 aaagaggttc atgtaaatgt tcttctatat agtcttgcac tttgcaaata cgatttagat
    15301 attctttttt acttttagca tttgtcatat atagccctcc ttattgtgta aaatgtgtat
    15361 caattaattt atagcaatat agtaataaaa ttttatgttt ttgtaattta tgataaataa
    15421 gatagcgttt aattttttat aattgataaa agatatttat aattaataaa agatataaga
    15481 tgccttatat ttatctttgc atataagtat agtcttcgta ataattagta taccatagtg
    15541 atttattttt aattgtgtat ttatataaat acacaactta tgatatggac gaattattat
    15601 gcaaataagc tgtaattaaa taaattgcaa tataaaccag ttgaaacata agttagggaa
    15661 atattatcaa agttattatt tagcataaga ctatagatgg aataaaataa gattaaaaaa
    15721 ttacatacta aatttaataa aatttttata ttaaacaaag tataaatttc taattatctt
    15781 tttatatttt cttaaatgct cgtaaagcct tattctatgt gctttcgagt atttttactg
    15841 taggaagata cttcacgttt ctttgcatat ttcctcatgt cttagctgtc agaagtggta
    15901 aataagtagt aaattcattt gtactactaa gcaacaagac gctcctgttg cttctcttta
    15961 ttcaagcgtt tcatttctgc cattgcagaa tcgaatgttg catgtgcgta atagttcagc
    16021 gtcatggcta tattagcatg tcccataatg tactgtaatg cctttggatt cattcctgca
    16081 tttgcatagt tggtacagaa tgtatgtcgc aaactatgtg gagtgatgtg tggcaattta
    16141 tcctcgttat acttattgta tttcttaaca agacctttca tcatgccgtt gtaatcactt
    16201 gccacttttg gatagttctt tctattaaga aagaggaaat cactatatcc atcaatctca
    16261 acacgcttat cattctttcg attcgctaac actcgcttaa atgcttgata ggcttcttca
    16321 accataggaa cttgacgttc gccacttttg gtctttggtg tttcaatgta gtacccaatt
    16381 tcagtatctc tcaatagctg atggtctata ttgacaagac gattctcaaa atctaaatct
    16441 ggaagtgtca aaccaccaaa ctctgaaata cgaagacctg tttttaagag tatcagaatt
    16501 tcatcataat ttttgctgta ggttttatca gcttttgcaa aggctaacag tttttcttcc
    16561 tgttcttctg ttagtacggt cttagggaca gtatcatcat caagaactgc tttcagttga
    16621 aagtcaaatg gattcttccg aacacaatca tcttgtatag caatatagaa tgaagccttt
    16681 aaagaacgtt tgtagttatt gatggtttga taagcataac cattttcact cattctaata
    16741 gcccattctt tagcgtctga tggcttaata ctgtcaatac ttcttacacc taacttgtct
    16801 ttcttcaaaa tatccataag atatttgcgt ccagtttcag tgttttttct aacctttggt
    16861 ctttgagcgt tctgttttgc gtaaagctgg cagagtgtca ttttctttcc tacaacatca
    16921 ataccatcat gaatgtcttt ctgtaactct gcgattttct ctctaagtga gatacaatca
    16981 cgctttcctg ctggtactcg gtctgtagcc acaagtttcc acgagtaaac aaattgcggt
    17041 tctccaaatg aatctatata tttgtataag tatcttccgt cttttcgttg gctctctcca
    17101 gtctttaaga ttcgaccttt attgtcacgt cttttttctg acatggcatt tgctcctttc
    17161 ctttatggaa agagccttga tacgacttaa tactatttta tcatatacaa gaccctttgg
    17221 cgacgctaga ttgcgtccaa tgtatctata attttttcaa attgttttcg tttaatctga
    17281 atacgattgc cattcataat cagccaattt gcatttttat tttcctctgc caagcgtcgt
    17341 agcttgtttt cgccaatacg aaaatatttt gacgcttctt caatggttag ggtataacgt
    17401 tcccaaatag gaatgtcagt ctgcttcata aaatcctcct ttccaaatca cttatttgga
    17461 tttcataaaa gttgttttac cagcaatcga acagctttag caaagctcac gggagttcca
    17521 cccctgcatg gttctcatgt agccatactc attgcctgcg acggttttat cacgctcgga
    17581 ctattgactg tatgggagta tcattatcac gataagaatg tcgttgcagg caatcctgct
    17641 aaagattgct tctcggatca ctaacatgaa tcgctcgcta tctttataag ataggtcatg
    17701 gcggttagtt ccgttggctc ttttcttatc gaaacgtatt cgattacttt tattcagttt
    17761 tcaaagaaca atggctcgtt agcctatcaa aacacattga aagctcaata tgctttggtg
    17821 gaataacaaa cctccctgtt cgggaagcgt ggaatggttt agcacgcttc cacgaaagga
    17881 gagaggatat tacttaattt caaatgacaa aatctttgta atcagtctgg tttccattct
    17941 tccacgtaag acttcatcaa cgaccatact ttgattgcca tattcatctt tcataagtcg
    18001 tagggaacgc ttcgttatgt accctctgta atgatgtaga atctggttaa tcgcttcggt
    18061 atcgccatct gttgccttta caatgagagg aaagggaatc ataggatatt gtgttttcat
    18121 tcttcaaatt cctccataaa ctttttaatt aaggctagtc cactggttct atgccgatag
    18181 acagtagaac ggttcaattt caacaggtct gcaatttctg aatcgctcat gtccataaag
    18241 taaaacagca gtagaatttc acgtttcttg tctggcaact cacgtaatgc ttcactcaac
    18301 aaatcatttt caacgcctac tgataaccca ttgagtgtaa aaatctgaaa gtcagttgaa
    18361 tagttatctg ttgtcgcaaa ctggctaaca agataatcgc caacatccga aaaggacacc
    18421 tcacgctttg caatccttga aagataaagc atataattct ttcgctcgtc ttccatagca
    18481 cgtttacaga tatagtcaaa ctgattttct attgtggtct gaaaagaaga tggtttcatg
    18541 tttctcaccc cctttctgtc taggaaagga agtgagcctt gctcgtttat ctcctttcac
    18601 tcttagtccc aatgtgaaag ggggatttgt tgcattactg ataaataaac tttgtaaaaa
    18661 agttctgaat agccaaaaaa gcatataaac agatttattt ctctgtttac atgcttctgt
    18721 tattctatct atatgattta taaaaccaca ttggtggacg tacttatcta ttgcagatag
    18781 acgacttttt ttgacaagaa cccaatgtaa ggaaatttat tgtatatgat gtacttcatg
    18841 gcgacgttga cctccaacaa accgccattt ggaagtaata tacaatattt taacagcgta
    18901 aatagcacta ccatataacg gtttttttta ttggcgttta gtagtgcttt ttattaaata
    18961 taaacctata aaccatataa cacgtttttc tatacctgtt tttaattcag taggaacaat
    19021 aaaatgtata gaggtggtct actatgcgta aaaaagaaga taaatatgat tttagagcct
    19081 ttggtttagc cattaaagaa gctcgattga aacgaggttt aactcgtgaa caagtgggag
    19141 cattgattga aattgaccca cggtacttaa ctaatattga aaataaaggg caacacccca
    19201 gcatacaagt tctttatgac cttgtatcgt tacttcatgt ttccgttgat gaatttttct
    19261 tacctgctaa taacttggta aaaagcaccc gacgattaca gatagagaaa tacatggata
    19321 gctttacaga caaagaacta tccttaatgg aatctttagc cagcggtatc aacgaagcaa
    19381 gaaacatcga agactaatta aaagaatcca tacataacgg aaagagccga taaaatgaga
    19441 ttgtattaat ctcattttat cggctctgcg tctttgcgtc tggctctgta atcacagtta
    19501 ctttgaactg ctttatttca attaaatttt cttgtctgca tttcggacaa tagaggggga
    19561 atttttttaa ttcagtatct tcccttatct ttaatcgtgt tttatttcca catacaggac
    19621 acaatatcca cttgtagttt ataataacta tctcctcctt tacactttaa ttcaaatctt
    19681 tattaaaaaa tatttcatct tatttaacaa gaaaccatat ttatataaca acataaaata
    19741 cactaagtta ttttattgaa catatatcgt actttatcta tccgactatt tggacgacgg
    19801 ggctggcaaa caggttcacc ggtagtaaca tggtaccctt ttaactctgt taaacaaaca
    19861 ctacgtccat ttgtaaagaa agttaaatca ctacgatatt cttgaataca ccgagcaggg
    19921 atttctccac taagaatgac ctcattattt ttcaattgag tgtctacgat gttcgcacaa
    19981 tatttaggag catcgttgta tgctcgtgaa agatattcct gtggcgcata aattttaaaa
    20041 ctaagatatg gctctaacaa ttctgttcca gcttttttta agacttgttc caatacaata
    20101 ggagcaagca tccgaaaatc tgctggggta ctaacagggc tatagtataa gccatactta
    20161 aaacagattt tacagtccgt cacattccaa ccatacaatc cttgttcaca gccatagcgt
    20221 atcccttcca taactgcatt ttgaaatgat tgatttaagt atccaagaga aaccgagctc
    20281 tcatactgca ttccacttcc caacggaagc ggtgatacag ataaaccaat ggaagcccag
    20341 aaaggatttg gcggcacttc gatgtgaatg gtatattctg cattttttaa cggtctctcc
    20401 atataaatga ctgtaggctc ttttagttct atctccacat gatacttttc ttgcaacagt
    20461 gcactaatca cttccatttg tactttccct aagaaagaaa gtataatttc atgtgtcgta
    20521 gaatccacgt aatatcgtag aagcggatca ctatctgaga tttccaaaag ggcatcaagc
    20581 aacatttctc tctgttcagg tttactcggt tcaacagttg tttgtagtag agggtgcgga
    20641 ttttcaatct tttttctctg tggcaatagt tttgtatctc caagaacact atttaacttc
    20701 aaaaactcat tttgcaaaat aacaatttct ccagaataag ctctatcaat cttacataat
    20761 tcaccattta ttgaagtata catttctgta acttttattt tttctttttc tgatactcta
    20821 accgaatctc gtaaatgtag tactccacta taaaggcgta tatatgcaag acgttgtctt
    20881 ttttttgtat attcaatttt gaaaacattt ccgcaaagtt cagacggacc tcgatgtgtt
    20941 gatgaataaa atttattagt aataacttct ataaggttat caatccctat attacttttt
    21001 gcacttccat gataaagagg gaacagagaa caattctgaa atcttatgct ttcctcttgt
    21061 tcgagttcca atgcttctaa tgatttaccg gacatatatt tctctaaaag gtcatcgttt
    21121 ccctctatta ccgtatccca ttgttcagat tcggtaaagt tcgtcacaca catattagga
    21181 tacagttcta ccttctgttt gattacaatt tcggcagaaa gtttctcttt aatatcctga
    21241 taaaccgttg ataaatcaat tccattttgg tcaatcttat tgataaaaaa gattgtggga
    21301 atccccattt tcctaagtgc atgaaataat atacgagttt gtgcttgtac gccatctttt
    21361 gcagaaatca gtagaattgc cccatctaaa actgataatg aacgatatac ttctgctaag
    21421 aaatccatat gtcctggcgt gtctatgatg ttcaccttcg tattttccca ctgaaaagag
    21481 gttattcctg tctgaattgt aattcctctc tgacgttcta aaagcgtatt atccgtcctc
    21541 gttgtacctt tgtccacgct tcctaattct gtaatcgctc cactgttata taataagctt
    21601 tctgttaagg tagtttttcc tgcatcaaca tgagctaaaa ctccaatatt aataattttc
    21661 atgtgatttt cctccattca aaaacccaaa agggcataaa aaactaagcc ctcctaaaaa
    21721 aggacatcta attatttgtt cccgctatca aattgacagt ttatttaaga ataccttgcc
    21781 gcatatttat taactccttt taaatagtca cttaaataat agcacgtaag agcatatttg
    21841 taaaggaatc tccaattttt tatcaaaaag agtacatgat tacaaagtat ctgtaatcat
    21901 gtaccaatat ttgttatttt acaatcttcc aattactccc gttcttttca agtaccaaat
    21961 caaattgaga tacctgcgtt gctttggtct gctggtcgat atactccact gtcagcgata
    22021 ccgtgacttg attatcctta cgattgtgaa taggatttac cagttcttga aagatgtact
    22081 cttttccgat tggttttaat atcccgtcat tcacatagta ggaaagttca ctggctgtcg
    22141 ctgtaggata gagcttgaag aacgtcgtta aaaactcatt gatttcattg gttgtaatgg
    22201 aatcaaccgt cccctcactt tcaatggctt ttggtttata acttgatttc ttaggtatgt
    22261 tggtaatggt cggattctta accagtacca tatttccaga accatctaca tagacactca
    22321 ctatataagc agagtggacg gtctttgtat tttctccctc tgtaatgagc tggtctacac
    22381 tgtaggttac attaaactca ttgtcgccag ttggctctac cgtccatatc tgaaatcctc
    22441 ttacagaaga cgatacagga atatctttgc gtactgtatc aacattgaga gcttgaagtt
    22501 catctgtcag atagcctttt agactttcca ttcgattatc aatggactta tcggattgct
    22561 cccatgaata gtagactttc gcaaagttct ctacaaaatt ttctacatga tgagtatcaa
    22621 cgtattcctt ttctatgata gttgtttcgt gaatagtatg agtatctata gctgtaaagt
    22681 gcttgaatat cgcaaagctg aaactaagcc ctaaaagtac ccacaaggca atcacaacct
    22741 ttttatgagg attgacctta tagacacgag gtttcttttc ctttggtatc tgtttttctt
    22801 tattctgatt ttttctaaat ttcatcatta aatcttcctt tctcattgtt tgattcgtcc
    22861 tgctcccact aaatgctgtt gccagtaggg gcttgttaag tcggcataac cgattgggtc
    22921 gcctgcatga aacatacggt tattgccaag gtatatccca acatgagtaa tataagagcc
    22981 agcgttatag gtagaatgaa agaaaaccaa atcgccagct tgtgcttccg atagtgggat
    23041 atgctgggtc acatcatatt gctgttgtgc ggttcgtggt aagttaattc cagcttttcc
    23101 atacgtccat tgtgtcagtc cgctacaatc aaaagaagta gtcggggaag ctccaccgta
    23161 aacgtatcgc cagccctcat atttcagtgc ttcgtccatg atggcttgta ccgtatcatc
    23221 atcaaactct gttgtgacaa gatactgcgt taccagttgc acataaaaca tattgccata
    23281 gttgtatcgc cagcccccat tgataggtat ggctatggga ttggggtaag acactttttc
    23341 gccacctgaa tactcttttg agaaactttg agccagttca aaggtatatt tatttccacg
    23401 attagccaca taccctaaga aaccaccacc ataattgtag gactggataa ccgattctaa
    23461 atctacactg agcctttcgc tactggctaa taattcactg aaatacttca caccttgctt
    23521 aatggattct tctgtactca atgaattagg tggaagaccg agggattccg aggactgcat
    23581 aacatcttcc gcagtaccgc ccgattccac ctgtataatc gcaagaagta tgttgacata
    23641 ttcttcaacg ccatattctt tggcatattt ttctaccata ggcttatgag ccagcacttc
    23701 tgcggaaaca ttcacacctc cataatgaat attggaaatt ccgctgtcct gttcatctga
    23761 aaataaaatg gcaacaaaca gaagcagtga gaagaccatc aagaataatc cagaaccacc
    23821 aatcactaaa gttttcaact tcatggtttc ttaccgactt tcttaatggt ggcggttttg
    23881 attggtggtc tacttcttgt attttgtagt ggtactcttt gaacagtaga cggacgttct
    23941 tttgtgattg gacgttgtga agttctatct gctgtagtgg ttgaagttgc tggcttttga
    24001 acggtttttt cttgaacggt attgccttgg cgttccactt ttggacttga aaaatcggac
    24061 ttaactgctg gacgctcttg tttggcttgt tgagattcct tatatgaagt ctgaatatta
    24121 gactgttttg aggtctgttc atcatgatat tgttcttgtc ttgtagtcgg tctttcatga
    24181 acagaagaag caggctgttt tttctgtttg acctgttcca tttcagagcg acgcttcgca
    24241 atggtttttc gcctttgttc ctgctgttcc ttgcgtccac tggctctgtc cgctttggtt
    24301 tgagaaatac tactggttaa atcacggaca ttctctttta ctttggattt tccttgatat
    24361 actgcatatc ttgcattggt cggcaaatct ttaacctgtt ctttcaaacc actagcagtg
    24421 tctaccattc tgtctttggt atcagctact gtaccgatgg tttgaccgat acgttttcca
    24481 agtgttgatt tttcctttcc gtctggtcgg gagtgatctg cttgtgtcct tgcagaactc
    24541 cccgaacccg actgtccttt tttacctgta acaatggcag acccagcccc tagagtagtc
    24601 atggaacgtc caagtttccg ctgtagacgg tgcatgtgag cgtgcataag catacgaggt
    24661 tttctcatca cacgacttcc cacactttga gaatcgttac tctgtagaga aaacatactc
    24721 attaaatcgc ccagcttgaa gtagattcct gcaaaggtca caatctgtag aaaagcaatc
    24781 aaaaagaacg gataaccagc cgataaggta tagagcatgg ttgaaatact aaatgctgtc
    24841 gtaataatca atgtgattcc agctcgtgtc aaaatggtat taaagagctt tgttatggct
    24901 cgttttgaca taccatcaaa tgatggaatc atgcttaaaa taaagctcac aggcagaaac
    24961 atagcataga tgataaaaag tacctgcgag aaaatcatga ttcctgttaa taggaataca
    25021 aatatggaaa tcccaatatt gaagacaaat aggaagaaga ctgtacctaa acggttaatg
    25081 gtctttgtaa tggttagatt ggtattgctt ctgtcttcaa tttcttccgc aacaattttt
    25141 tctctgtctt cgccattgtt ggaatctggg ctggtggaga gcaggctttc cacacggtca
    25201 ataccgatac tttcaatgtc tgaactgttg tattgaagca gtagccacgg ttgctgaacc
    25261 tgtatggaaa acaggctatc tctgattaag tccacgctgt ccttgccttg actatcggaa
    25321 tggggcatga caatcttcgt gccaagtgat aaactggcat tactgatgtc tgatgaaaag
    25381 tcattgattt ttttaatgta gtcgggagcg taggcaataa aggaagccga taggataaac
    25441 accagcacaa aattcataat ggcatgaatt gcctttgtgg tttctctctt tatcagtccc
    25501 gtataggcaa cataaacccc aagaaccaaa atcaagagta agaggaatcc aacatagaaa
    25561 ccctctgttg aaaatccgtt tgcactcaca ccagctaagg tctgcatatt cttaccaatg
    25621 gaatctgctg tagcggaaat gaagtctaag gaataggctt cctgtactaa gtaacctgtc
    25681 gcattggaaa catacaaact gattgtccaa ataaaattgg taatggcata tagtccatac
    25741 atgacctgtt ttccaatccc gtccgaccag ttccacggaa gccagcccca gctattatcc
    25801 acataaaaat ccagttgata gttttcaagt gggtatcggc tgtattcatt tgccacattg
    25861 accgtatcat ctaccaagcc cgcagcttga accaccgttc ccagcatggc taaaagaaaa
    25921 atggcaatca caagtgtgaa agccactgtc attgccactt tacctagacg tttcagcgtc
    25981 cagtttgatt ttattctgtt tactattgat ggtttcacat ttacacctct tttcgcacag
    26041 gtggtctggt atcaaaggca tggagcagtt cttcaaatac agggtggaac tgtatcacac
    26101 cgacacgacc atataaatca ctgataaggc attgcccgtt ttccaaatca cgcaatcgct
    26161 tctgattgtt ttcgtcctct gggtctacac caaaaaaggc taaggtcttt ttaatctcgt
    26221 taaggtcagt ggaacgaaat gcaaatttta agccgaggtt atttttcagt ttttcatcta
    26281 agaggtcgtc tgtattttgg gtcacgaaat ataccccagc gttcatagca cgaccagccc
    26341 gaaccagctt catagatagt gtttttcctt gtgctacctg taaaaagctc catgcttcgt
    26401 ctaaatctac aatcttgaaa atgcttcggt ctgtatggat aaagtctaaa gcaaaggtac
    26461 taatgacaat cagcatagca acggataaaa gctccatagt ggtatattcc tcaaaggaag
    26521 tttccttgtc gggaagtacc aagtccgcaa cctgtataat gttcagttgt ttttctaagc
    26581 tgatagactg ctccacataa ccattactga ataataaatg tgcaaagtca tagtctgtaa
    26641 aactttcgat atggtcggct atactggtac ttagtggcgt attctcaacc cgtaattcct
    26701 caatcacttt catcaaccct cgtacttcac tattggttac tgcacgaatg gcttttctaa
    26761 ggattgggaa gcgttcccca tcacgagagg aaatccccgt aaggaatgtc agaatatcaa
    26821 tagccagtga ttcagaatct ttgggatttt tcataatcac ataagggtca agtaagcctt
    26881 tgtttttctc atcagaagtc agagtgacga tattgatttc atgggaaatc tctggcaagg
    26941 tttctttcca tctgccacgt tctgcttttg ggtctacaat cactgcttgt gccccataaa
    27001 gcaccgcata atagacgata aggttattcg caaaggattt accaccaccc agcgaaccaa
    27061 caaaagccga cgctaacgca ttggttactg aacccttaac cccttgactg gcaagagcag
    27121 gtttcagata gacattgcgt ccagtatcta agctgtagcc aacataaatc ccctcatttt
    27181 cccccagcat ttgagtagca ccaaaaccta aaccagcgag gaaatcagag gtcacgtatt
    27241 gaatataatc attcatataa cgcttgctgg caggtaaaaa ttcttcatgt aagccgagca
    27301 tatccccaaa tggtcgtacc agttttacgc ttaaatcgtc ataaaaatct ttcacttcat
    27361 tacaacgacg tttgagttcg tcaagatcat ttgctgatac ccttaccaca taagacagct
    27421 tgtacataga ttccttgctt tggtctaaat tggtttccag ctcattcaca ctttccagag
    27481 cttccgccac attggagctg gtttcattat cactttgcca agcgtggtta tccaagtctt
    27541 tcagttcttt ctttttattg cggacagtag atagggcttt acgattcgct acaatttcca
    27601 cattcattga cgtatcaatc gggaatgtaa attgctgttg ctggtagtag aagatttcag
    27661 aggacgggaa gtccagttct ccgacaatgc tgttaatggt aaagtaagct acatagacgg
    27721 tttcatcttc ctgctggatt ttcaaatatc gctgtttttc ttccaccaaa cagcgagtag
    27781 gcttaatcaa gtcatagtat ttaatcagcg tttcattatc cagctttttc tttgatagat
    27841 ggtactcata ctcttcatag gcagtgcctg tctgtccgta aaggtgttca atcagatagc
    27901 cgaagtcgtc cttatctaac ctgcggattt tgaaacgacg agagatttta ttttctaaga
    27961 gcttttccat cttctgaaaa cgcaggattt catcattact catactaaca aaatcgccca
    28021 tcagcttatg gttcacatca tagacaaaat cagacaaagc attttttgct tcaacggtaa
    28081 gacttttcat agaaaactcc tgatcgttga gaagcaactt aaagccgata aagaaacggt
    28141 agttcacttg attttcgcca atcatggata ttaaagcgtc tgtctgttgg tcgattttgt
    28201 cataggcaac cgctttgagc ttgccagtga cttcattttt ggaacgctct tgtgcagaac
    28261 gtatgctgga ttctgtactg atttgtaaag catgaatttt gccatcacga ttttgtgcga
    28321 taagctgtct gaaagaatca tgcacttgta ttttctgttc tggacttaga aatgagtaat
    28381 tgtaaggaac aagctcatag taagcataac attccccgtc tttattccag acgagattgt
    28441 tttcaatgta tttaattgga tatgccataa aattcactcc taactgctgt aatggcttct
    28501 tgtggctggt ttctgccaag cgttactttt tttcctgcat aggtcagctt tggtcgcagt
    28561 gcataagcaa tgacagactt caaaaatcca taaggctttt taccatcaaa agtttttgta
    28621 gacataaacc atgtgaaagc cacaggaatc ccaaagtatt tgagaaatgc tccctctatc
    28681 atggaaagag ggggcaagtt gccaagtatc atcactgcaa agagtgacac gacaaaccat
    28741 gtcatttgcg taaaggttat gggaaacgga agtctaaaat cattgataga atacagtacc
    28801 ttttccacag accagatact ggtatagctt cgtattttct tcatgtaatc aatcctttca
    28861 taaaaaatag gggtagctga ttgagccacc ccgtaaaata gaaaatctgc cagtagtaat
    28921 gtaccgacag atttaataga cgatttcaaa aatcccatga ttggttgaga taaacgttcc
    28981 tgaaaggtct aaatcccgac cataggcttg ataatcaata tagttttgaa gactagctgg
    29041 tacttcgcct aaagcacccg tttcttcaat gtagtagcgt gccacgtcat acatatcatc
    29101 acaatcggaa tgaatgataa tatcctcttg atgttcgctt agttcttcaa tgcttgaaaa
    29161 atgagtgagc agagcagata gctccgattg taattcttcg ggtaattccg ataccatttc
    29221 ccatagtcga ttgagttcgc caatggaagt gtattcgtca accgtaaagg gtaactcgta
    29281 gtcatgaatg gcgtattcct catattcatc attcaagccg attttctctt tgacttcctc
    29341 aaagtcaatg ggaaaggtaa accacgcacc gaccaattcg ccctcattgt atttgcctaa
    29401 attcgcaata tagacttgca tatcgtccat atattcacgt cctttctttg tagagattca
    29461 aaaatcccta ccgcacttcg tttggtgtac cattcctttg cggaacataa gaaaaccact
    29521 tatattccac aaaagaacgg ttttatttaa gcaccaataa tgcgattgaa tagctctagt
    29581 aaaatgtctt ttactccagc agcgttgaag actaagccaa ccgcaataat cgcaataatt
    29641 aaaaagccaa tcagtttgct aaactcacgc ttgaagccaa gatacaagcc aatcacaacg
    29701 attgctaaaa gcaccagtga ttgagcgttt gatagaaacc agt
//
LOCUS       DAEPUT010000046        28530 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.048, whole genome shotgun sequence.
ACCESSION   DAEPUT010000046 DAEPUT010000000
VERSION     DAEPUT010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28530
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.048"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            145..495
                     /locus_tag="KRL22_002239"
     CDS             145..495
                     /locus_tag="KRL22_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH1272727.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            514..2157
                     /locus_tag="KRL22_002240"
     CDS             514..2157
                     /locus_tag="KRL22_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBH1272728.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFTKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            2238..4295
                     /gene="recG"
                     /locus_tag="KRL22_002241"
     CDS             2238..4295
                     /gene="recG"
                     /locus_tag="KRL22_002241"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBH1272729.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKNKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            4354..4908
                     /gene="rsmD"
                     /locus_tag="KRL22_002242"
     CDS             4354..4908
                     /gene="rsmD"
                     /locus_tag="KRL22_002242"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBH1272730.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            4910..5407
                     /gene="coaD"
                     /locus_tag="KRL22_002243"
     CDS             4910..5407
                     /gene="coaD"
                     /locus_tag="KRL22_002243"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBH1272731.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            5411..5935
                     /locus_tag="KRL22_002244"
     CDS             5411..5935
                     /locus_tag="KRL22_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272732.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            6279..8198
                     /locus_tag="KRL22_002245"
     CDS             6279..8198
                     /locus_tag="KRL22_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1272733.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKNVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            8211..8498
                     /locus_tag="KRL22_002246"
     CDS             8211..8498
                     /locus_tag="KRL22_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1272734.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCDVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            8631..9890
                     /locus_tag="KRL22_002247"
     CDS             8631..9890
                     /locus_tag="KRL22_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBH1272735.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFVGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILICNYFNIFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISRFIGSLFGGIL"
     gene            9893..10633
                     /locus_tag="KRL22_002248"
     CDS             9893..10633
                     /locus_tag="KRL22_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1272736.1"
                     /translation="MKFKYIDEIRRLIDVIENEEKVNMEKAVQILVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            10956..12266
                     /locus_tag="KRL22_002249"
     CDS             10956..12266
                     /locus_tag="KRL22_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH1272737.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            12364..13281
                     /locus_tag="KRL22_002250"
     CDS             12364..13281
                     /locus_tag="KRL22_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH1272738.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            13297..14106
                     /locus_tag="KRL22_002251"
     CDS             13297..14106
                     /locus_tag="KRL22_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH1272739.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            14164..15912
                     /locus_tag="KRL22_002252"
     CDS             14164..15912
                     /locus_tag="KRL22_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HBH1272740.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNVPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDMLVEQYLPQTFWVEGQVPEDFEENNFNIGIDIFKSFGYEDEEKACTIDVP
                     VEVKNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIIDNYLKELASLGEKV
                     ATIIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            16174..17196
                     /locus_tag="KRL22_002253"
     CDS             16174..17196
                     /locus_tag="KRL22_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HBH1272741.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGITKEAPEASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            17201..19507
                     /locus_tag="KRL22_002254"
     CDS             17201..19507
                     /locus_tag="KRL22_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1272742.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMRILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTILVSKPSEKKEKSIDEFEPMEYI"
     gene            19479..20594
                     /locus_tag="KRL22_002255"
     CDS             19479..20594
                     /locus_tag="KRL22_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272743.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVRIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVLGEF
                     EGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     RFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQKGKLTL
                     SNKAKPGQIILQVNVDDKFKIGKKITLTESWSVNKKDKDGVPYTLVYPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            20612..22030
                     /locus_tag="KRL22_002256"
     CDS             20612..22030
                     /locus_tag="KRL22_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HBH1272744.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            22045..23253
                     /locus_tag="KRL22_002257"
     CDS             22045..23253
                     /locus_tag="KRL22_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272745.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCK"
     gene            complement(23334..24722)
                     /locus_tag="KRL22_002258"
     CDS             complement(23334..24722)
                     /locus_tag="KRL22_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBH1272746.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEIFSKKNIS"
     gene            25063..26397
                     /locus_tag="KRL22_002259"
     CDS             25063..26397
                     /locus_tag="KRL22_002259"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HBH1272747.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITERQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTSQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(26526..27443)
                     /locus_tag="KRL22_002260"
     CDS             complement(26526..27443)
                     /locus_tag="KRL22_002260"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBH1272748.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            27651..>28530
                     /locus_tag="KRL22_002261"
     CDS             27651..>28530
                     /locus_tag="KRL22_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HBH1272749.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKR"
BASE COUNT        11128 a         3070 c         5087 g         9245 t
ORIGIN      
        1 attttatcca aaaacttttc taggtttaaa ttataccata tttatagtat gatatgatta
       61 taattttata taataaataa gtaaaaatag taaaaaataa attaagaaat gtttttaata
      121 aaaataagct taagggggtc aaccatgagt gcaaaggtaa cgaatcaata tggaaatata
      181 gaaatagata atcaagtaat agctcaagtc gtatatagag ctgcaatgga aagttatggc
      241 ttagtaggtt tagcatataa gtctaaagga atagtagagc tattaaaagg cgagaacgca
      301 actaaaggtg taagagttga ggaagtagaa gaagatgcca tagcaatcga actttatgtt
      361 ataatacaat atggtacaaa tatatctact gttgccaata atataataga tagagtaaaa
      421 tatgtagttg aaaaaatgac tggcgtaaga gttactagaa ttgatattaa tgtacaagga
      481 ataagagtta agtaatttca taggaggaaa caaatgattc aatatataga tggtaaaagg
      541 ttaagggaga tgtttatttc aggtgcaaac aatctccaaa acaataaaga gttagttgac
      601 aagttaaatg tattccctgt accagatgga gatacaggaa ctaatatgtc attaacaata
      661 tcttatgcct taaaagaatt agcaaaagtt gaaaatgata atatatcaga tatcggaaaa
      721 gcattatcta aaggttcttt aatgggagct agaggaaact caggagttat actttcacaa
      781 ataatcagag gtatagctaa atctatagaa ggaaaaagta aattatcaac agaagattta
      841 gcaaaagctt ttaaaaatgg ttcagacaca gcatataaag ctgtaataaa accaattgaa
      901 ggaactatac ttactgtagt tagagaaagt ggagagtttg caataaaaac tgcgaaaaaa
      961 gagaaagatg tagtaaagtt tttaagtatg cttgtgaagg aatcaaattc ttcattagaa
     1021 agaactccag accttctaaa gaatctaaaa gaagctggtg tggttgactc tggtggaaag
     1081 ggtcttgtac ttatatatga aggaatgtta gcttctataa aaggcgataa catagaaata
     1141 aaaaatgttg acctagatac taatatttca acaagtatgg attttacaaa gagtactact
     1201 agcacagatg atataaaata ttgctattgt acagaattta ttttagaaag ttctaaggta
     1261 gaagatacta aaataagaga cataatgatg gcttatggtg atagcctagc agtagttgga
     1321 gatgatggag tcataaaggt acatgtacac actaatgacc caggaaatgt acttcaagaa
     1381 gctctaaagt acggtcaatt attaactata aaaatagaaa atatgaagtt acaacatgaa
     1441 aatacattac tggatgtaga agaaaagaaa gaaaatgata gtgaaccttt agaagaagaa
     1501 aaagagtttg ggtttatagc tacttctatg ggtgaaggtt tggcaaatat atttaaagat
     1561 ttcggagttg accatataat agaaggtggt caaactatga atccaagtac tgaagatttt
     1621 atgaatgcta taaagcatat aaatgctaaa aatatattta ttttcccaaa taacagcaat
     1681 ataataatgg ctgctaatca ggcaaaagaa ttgagtgata aaaatataat agttatacct
     1741 acaaaaaata cgcctcaagg atttgctgca ttagtaactt ttaatggaga attaagcgaa
     1801 gatgaaaata aagaagctat gatgaatgct ttaaactcag ttaaatcagg tcaagtaact
     1861 tttgctgtta gggatacagt gatgaacgaa attgatgtta aagaaggtaa tataattgga
     1921 attgcagaag ggaatttatt atcagcagga gattatgtgg atgaagtaac atcaaacctt
     1981 attgaaaagt tggttgatga agatactgct ataataacat tattctttgg tgaagatgtt
     2041 acagaatctc aagcaaatga actacgtact tctttagaag aaaagtttga agatgtagat
     2101 gtagagttat attatggagg acaacctctt tattattact taatttcagt tgaataatga
     2161 ttataagaac ctgtatgacc aagtagcttt tataaaattg gttgtacagg atttttgtgt
     2221 agtaggtgat atatttgttg gatttatata aagatgttca atatgttaag ggaataggac
     2281 ctaaaaaagc agataaatta aataaactgg gtatatttac actaaaagac ctattgtatt
     2341 attttccaag acaatttgaa gatagaaata atctaaagaa aatagcacaa ttagaagatg
     2401 gtgagaaagt tacgataaaa gcagtaatat caagtataaa tacatttagc ccaaaagaag
     2461 gtatgacttt aacaaagatt gatgtaaaag atgagacagg ctcggctaaa ttagtgtttt
     2521 ttaataagag ttatataaaa aatacttttc gtccaggaga ttcaatatta gtttttggga
     2581 aggttaagaa aaaatttaat aacttagaac ttacatcatg tgaattagaa tatcttacta
     2641 attcacctaa gaatacatgt agatttatgc ctgtgtacca gcttacatac ggtgttacaa
     2701 ataaagaaat tatgagtata attagaacag tacttgaaga taaagaatta attatacaag
     2761 aatatatgcc acaaagaatt atagaaaaat ataggctatg tagtatagat tttgcagtta
     2821 gaaacataca ttcaccaagt agtaaggaat cattaaaaat agctttatat agaattgtat
     2881 ttgaagaatt acttatacta caactagggt tgtttgtatt taaaagtggc agaaataaag
     2941 aagatggaat aaagtttgaa acaagtaaag acttaaaaaa aataataagt gctttaccat
     3001 ttaaactgac taaagctcaa aacagggcat tagatgaaat tatacaagat atgaatttag
     3061 agaaaataat gaatagattg gtacaaggtg atgtagggag tggtaaaaca gtagtagctc
     3121 tcttagcact tgcaaattgt gttttaaatg gttatcaggg cgctttgatg gcacctacag
     3181 agatattagc agggcaacat tatatttcac ttactgagtc tctaaaagat tttggaataa
     3241 atgtaggtct attaataggt agtcttacaa aaaaacaaaa ggatacagta ttggaacaaa
     3301 taaagaataa tgagattgat atattaatag gtacacatgc actaattgaa gataaggttg
     3361 aatttaataa tattggttta gttataacag atgaacaaca tagatttggt gttatgcaaa
     3421 ggagcaaact ttcattgaaa ggagcaaatc ctgatatatt agtaatgaca gcaacaccaa
     3481 taccaagaac tttagcactt atactctatg gagatttaga tatttctatt atagatgaac
     3541 ttcctccagg aagacagcca atagaaacaa ttgctattga aaaaagtaag cgagatagag
     3601 catataataa tcttgtaaga agagaggttg aatcaggaag acaagtgtac attgtatgtc
     3661 ccttggtaga agaaagtgaa gccatagaag ccaaatcagc agttgaactt gttgaggagt
     3721 taagagcgga atattttcac gacttaaggc ttgggttgct tcatggtaaa atgaagtcaa
     3781 gtgaaaaaga tgaagtaatg agacttttta aaaataaaga aatagatatt ttagtttcaa
     3841 caacagtaat agaagttggt gtcaatgtgc caaatgcaac attaatgata atagaaaatg
     3901 cagaaagatt tggacttgca caattacatc agcttagagg gcgagttgga agaggtagtc
     3961 ataaatcgta ttgtgtacta atttatgatt ctaaaacaga tgtatgtaga caaagaatgg
     4021 ctataatgga agagaccaat gatggtttta agatttcaga gaaggattta gaaataagag
     4081 gacctgggga attttttggg acaaggcagc atggtcttcc agaacttaag gtagcaaact
     4141 tatttaaaca tataaaaata ctgaagttag cacagcaaga agctcgatat atattgggtg
     4201 aagataataa tctacaatta aaagaaaaca tggcactcaa aaaagaaatt atagataaat
     4261 ttaaagatac attgaaagaa atttcattaa attaatttta aattgtgtta aaatattact
     4321 aatgtaataa tgtgctgaag ggagattgtc atattgagag taatttcagg aaaagcgaga
     4381 ggattaaaac taaatactcc aaaaaatgaa gatgtaaggc caactacaga tagagtaaaa
     4441 gagtctctat ttaatatgat aaattcatat ataatggaaa gtgaagttct ggatttattt
     4501 gctgggactg gttctttagg aatagagtgc ttatctaggg gtgccaagtc atgtactttt
     4561 gtagatatca gtaaggaaag catagatatt gttaagtcca atataaaaaa ggcaagagtt
     4621 gaaagtgaaa gtattatttt aaaccttgat tttaagactg caatagataa acttaaatta
     4681 caaaatagta aatttgacat aatttttatg gaccctccgt attataaaaa tatgtttata
     4741 gaagctattg aaaaaattga taattctaat ctattgaacg aagatggaat aatagttgta
     4801 gaacatgata cgaatgattt atttccagat aagatatgta aattggagaa aactagagat
     4861 aagaaatatg gaaatactac attaactttt tataagatgg aggcataata tggaaaataa
     4921 acctagaaaa gctatatttg caggaagttt tgacccaatt actaatggac atttagatat
     4981 tatttgcagg gcttcgaagt tatttgacga attacaaata ggagtattaa ataatcctaa
     5041 taaaaagggt ctatttagct ttgatgaaag agtaaaactt atagaaaaaa gtacaagcca
     5101 tttaaataat ataaaagttg tgacttttga tggtttatta ataaattact gtcaggaaaa
     5161 tgggattgga gcattagtta gaggtgtgag aagtggtgct gatgttgatt atgaacttca
     5221 gatggcgcat atgaatagag agcttaatcc agatatagag actataattt taccaagttg
     5281 tacaaaatat tcatttataa gttcatcttt aataaaagag gttttgctct ttgatgctga
     5341 tataaaaaat ttggttccaa agattgtttt ggaagaatta aagaaaaaaa ctagtggggg
     5401 taattgatat atgaagatag atttagaaat gattgaacta tttgagcagt tagaggagat
     5461 atttagaagt gcttctacaa tccctttctc acataaatgc acagtggata aagatgaggt
     5521 tttagcaata attaatgata taagaacttt aataccagaa gaagtaacac aggcagtatg
     5581 gattaataaa gaaagaaata aaataataag tcaagctaag caagatgcta caaatatagt
     5641 tgaacaagcg aaaaaagaag ctgagagaat acaacaagaa tatcaagata atatagagga
     5701 attaaagaaa aattctgaag atgtagtaaa ggcatatgta gaatccagtg aacctgttgt
     5761 tcaagcagac caaagagcaa aagatatagt tgatagagct gagagaatag ccaatgagat
     5821 aagaattggg tcaattgaat atgcagagga tgtgctttct agtgttgagt ataatttaag
     5881 agaaatatta gaagaagtaa aaagagataa agctgaactt agacctaaaa aataaatttt
     5941 aaataaataa aaatggagct atcacacaaa aaattccaat ttatgtgtga tagctctctt
     6001 ttaatatagc aattttttgt tatataattg tgctttttag attacttata tcttattttg
     6061 atattataat gtagtttaat cttttatttg ttgaaatcaa cttatttatt tgtataaata
     6121 atataggtta ttttcaaatt tttttaataa ttttaccact gtcttctttt agattagagt
     6181 tagactgtgc aaaattataa aataatacta aatcatgtgc aattatttgg tatggcacta
     6241 catgtagaaa atatagataa taaaattaag gaggtagtat gaaggaaagg gctaaaaaaa
     6301 tattagattt tattattaaa aataacaatg taacatcaca agaactacaa gaaaagttta
     6361 atgtttcaaa gagaactatt tattacgata ttctagctat aaatgaacaa ctaggaaaaa
     6421 gtggtaatat aaaaaatgta aaacacaaat ttatatttga aggtaattta tgtgatgcaa
     6481 ggaaaataat ttcaactgaa gaagataaat ttttagatag tgactacaga aaaactttta
     6541 tattaaacaa gatattactt ggcgaaaaaa tatcaataga aaaactaaca aatgaaatgt
     6601 tactttcaaa aaacacagta gtacaaacaa taactgatgt aaaaaaatac cttcaaacaa
     6661 tggggttaag attagagtat aagggaaagt acaaaattat aggtgatgaa tacgttatta
     6721 gagagctgtt tctgataatt gttcaagaaa atgtactgga aattaattct ataagtgagg
     6781 aagtaagtag tttcgataca aaaggacata taaaacttac tgattattct ttattaaatc
     6841 taactaagtt tgtggaattt ctaaataaaa ggataagaga tgggaaaaca ttatactcat
     6901 ataaatatct aaatgaagct aaaaaaatta gttactttag taattgtaaa gaacttttat
     6961 gtgaagaagc taatgaaaat gaacaagcct atatatgcac ttacataagc tcacttccca
     7021 gcttaaatag tgaagttaag gaagatgttg ttgaagaata tgtagataaa cttatagata
     7081 agtttgaagt aaatacagca ataaaattag aaagtaagca tgagtttaag aaaaatattt
     7141 taaggcacct ccactcttct tacaacagaa tacgatttaa gtttcctatt agaaatccaa
     7201 tgttagatga gactaagtat aaacatgagt cactttataa aattataaaa tcaattatag
     7261 agaatgaaga agagtttcct gtatttgagg ggataagaga agaagaaata ggatttatag
     7321 cagcgtattt tggaggatat ttaagagggt ctagggataa tggtctaaga agaaataaag
     7381 tcttactagt ttgtcctaat ggtcttatgg tatcaaagag tttggaaata caactatata
     7441 aatacatacc aaccatagaa atagtaggta tagtatccat taagcaacta aaagaagtaa
     7501 atgtatacta cgattacata attacaacta tagatataca aaatgtaaac aacgtaattg
     7561 ttgtaaatcc tcttttaaca tcatcagatg ttcaattact tatgaacaaa ctaataagtg
     7621 taaaagaaaa cgagaagtat ttcaatcttg aattaataat acaagctata agaaaaaatg
     7681 gagttatcaa taatgaagaa gcactaaaag ctgatttatt aaacataata cacaagatag
     7741 atgaaggaga gatgtatcaa ccaatgttaa aggaattaat taatgcagaa agggtcaata
     7801 taataaaaaa tgttagagat tggaaagaag caataaaaat agcctcaaag ccattgttag
     7861 aagataactc tatagaagag ttatatatag aaaatatgat aaagtcagtt gagaaatatg
     7921 gaccatatat tgttttagct gatagatttg ctctaccaca tgcaagttct aaagaaggag
     7981 taaacaagct tgctatgtct ttactaatag tagaagatga agttgattta ttaggaaaac
     8041 cagtaaatat atttatggta ttagctgctg tagataacac tactcacatt agagcattag
     8101 catcactatc agagatgatg tacgaggaag aaaatgtaaa actaataatt aatggtgata
     8161 aaagttcaat actagaactt ataaataagc aaaattagga ggaatgaaaa atgaagatat
     8221 tagcagtatg tggttttggt gtaggttcat caatggtatt aaaaatgaca atacaaaagg
     8281 ctctaaagca gttaggtata gaatgtgaag tagaaaatac agatataaat tcagctagag
     8341 gtgctgattg tgactgtata ttcacaagtc aagaattgtt aaatgaatta aaaggaactt
     8401 gtgatgtaga tgtatatcca gttaaaaagt acatggattt agcagaagtc acagaagttg
     8461 ttcaaacttt tttaagtgat aaaaatgata agaaatagta taagttttaa aaagtaaatt
     8521 taagttaatc agaataaaat aaaaacttac taaattcaaa aatagcaaga aagagaggag
     8581 ggatttagtg gtagaaaact taaacagttg acctatcact aaaaaatata atgcttgatt
     8641 ttatttcaaa taatatttta cgtaatccat ctatgttaat tggattaata gcagcatttg
     8701 gtcttgtact acagaagaag aaagcatctg atgttataaa ggggtcacta cttgcagctt
     8761 tcggaattat aattatggag actggaacag gtatgttagt tagttcaata gcaccaatta
     8821 atggagcttt ccaaagtata agtggtggtg cagtaacaaa aggtttaagt gatgttactt
     8881 ttactgcaag ttatggtgga attataggtt tagcaatgtt tgtgggttta gctattcacc
     8941 taatgatagc aagatttact cctattaaga caatcttctt aacaggtcac atgctttatt
     9001 ggttcccatt catatttgta gcttcaggag ttgaagctgg attaaatggt ggagtattaa
     9061 tagcttttgc agcagtatta tcagcactct attggtcaat aatgccttgg ttattaagaa
     9121 aatatgtgtt tgatgttata ggagatgatt cttttacatt aggtcatcca tctggttgtt
     9181 tagcacttat atcaggattt gttgctaaat tagtaggaaa taaagaaaaa tctacagaag
     9241 atataaacat acctcaaagt ttatcatttt ttagagaaat atctataagt ggtggaatgg
     9301 cagtgttttt aatgtttata gttgttggga tagtaatacc aggtgcgttt aaagatagta
     9361 atgagtttat tggaacgtat gcaataaagc aaggtctttc ttttggagca ggtcttataa
     9421 taatgcttca tggggtaaga atgctaataa atcaaataat gccagcattt caaggtatat
     9481 ctgaaaaagt tgtgccaaat gcactacctg cttttgactg tccaatatta tttaattata
     9541 aaccaaatgc tgtattaata ggatttttag ttgctatgct aacatctaca gctatgattt
     9601 taatatgtaa ctactttaat atatttaatt tgctacttat accacttgtt ataacttcat
     9661 tctttgagtg tggagcagca gcagtaatag gagaatcaca aggtggtata cgtggagcta
     9721 taataggtac agctatagct gcaatattta tggtagtttt agtaggaata tctgctgtaa
     9781 tttactcagg aactattcaa aattggatac taatatttgg aggtaatgac ctttcattat
     9841 ttggtataat cagtaggttt ataggttcac tatttggagg aatattatag atatgaaatt
     9901 taaatacata gatgagataa gaagattaat tgatgtaata gaaaacgaag aaaaagtcaa
     9961 tatggaaaaa gcagtacaaa tccttgttga agcaatagaa agtaaaaatg ctatattttc
    10021 atttggagct tcacatgcag gaatattaac agaagaatta ttctatagag caggtggctg
    10081 tgttcttata aatccagtat ttgcaaaatc tctaatgtta gatacagcac ctataactca
    10141 cacaagtaag atggaaagat tagaaggata tggtacagct ctagctgata aaactccaat
    10201 taaaaaagga gatgtagtta tagttcattc agtatctggt agaaatccag taagtataga
    10261 gtttgctatg aaagctaagg aaaataaggc aatagtaata tgtataacta atttaagtta
    10321 ctcaaaaagt gtatcttcaa gacattcttc aggaaaaaaa ctttatgaag tatgcgattt
    10381 agtgatagat aatcatggtc aaaagggaga tgcctgtgta gagatagatg gattaaacca
    10441 aaaagttagt ccaacttcta ctgtaatagc aactactgtg atgaactcta ttatagctca
    10501 agctactcag gaattagtta ataaagggct aaagaatcct ccgattttct atagtgccaa
    10561 tattgatggt ggagatgagt taaataagaa gatttttgat gaatataaaa gtgtaattca
    10621 ttatgaatat taaggttaaa aaaatatgtt aatgaacttt gaagtttatc aacaaagaat
    10681 attaataata tataataaat gctatcattt aaaagctgta ggtaaaaatc tacagctttt
    10741 tattattgta gattaaaaag atgcgtaatt aaattttaaa ttggagaaaa taaattggaa
    10801 ggtatcaatt ataaatatta gaaacgttgt catagaaaaa aactatatta aaaaaaagta
    10861 catagaaaaa actgattaga caataaatac atgctttgat aatattttaa atggagtgaa
    10921 aatgtgtaga attataatga aaaaagaaaa taaaaatgaa aaaagaaaat aaaatggagg
    10981 gaataaaagt gggtatgtta aaaaaattat gttcactagc tatggtagca attatgacta
    11041 caacacttat aacagggtgt tcaagtggaa atggaaaaga ttcaaaaaag gatggcgaaa
    11101 aagaaaaact agttctttgg atgccaccag tagaaaataa tatgaaggaa gtttgggacc
    11161 ctattttaga taaatttgag gaaaaaaata actgtgaagt agatttacag ataattcctt
    11221 gggataatta ttctgaaaaa tttgcaacag ctataagtgc tggcgaaggc ccagatgtag
    11281 gatatatgta tgcagaaatg tatccacagt ttatagaaag tggagcagta gaagatttga
    11341 ctaactatgc aactaaagag gataaagagc aatctattta tataaaaaca tctgaaatga
    11401 tgggtggaat gtatggtatg ccattccaag cagcaaatcc aggggtatta tactataaca
    11461 aggatatttt agaaaaatta ggagaaaaac ctcctaaaac atgggaagat tttaaaagaa
    11521 tttgtaaaaa agcaacacaa gatactgatg gtgatggaaa gatagaccaa tggggattag
    11581 ctcagggatg gggagctaaa acttttggta acttaaactg gaactggtat ccttatttat
    11641 ggcaagctgg tggagatatc tttaatgatg atttaaaatc ggttaaattt aatgataaga
    11701 gtggtttaga agcagctaat ttcttaaaag aattacaagc atatgtgcct gaagattctt
    11761 tatctaaaga tagtaatgaa atgatagaaa gtgtatttgg accagggaaa gcagcattta
    11821 caataatgtt atcttctgct gcaacaagtg tatttgatga atcattcccg gatttaaatt
    11881 ggggatttgt aactggacta gaagataaga aagcagcaac ttttggagca gtagaccatt
    11941 tatctttaat gtcatctgcg aaaaataaag aacttgcata caagttaata caacatatgt
    12001 taagtgttga atcaatgaca gaatttcata aagcaatacc aagagcacca ataacaaaag
    12061 gtgaaccata tcaaggtgat gaaagattca aagaaatggt ggaaaatgac aaaaatgtat
    12121 atagaccatt agtagtagga cctcatggag ttgaaatata tgaatattta tggaaagaac
    12181 ttcaaactat gatttcagga gataaaactc caaaacaagc gttagatgat gctgcaaaat
    12241 attcaaatga tttattagca caataaaagt ttaaagctgt aatatgttgt aaaggacttt
    12301 acagattaaa attagcattg tatttataaa tacaatgcta atatttatat tggagaggat
    12361 aaaatggaaa acttagttag agagtttgaa gaaaattcaa aaagaaaaaa aacaaaatta
    12421 aatattaaac catatatgta tatattgcca ttgggaataa ttttagtggc gttttatgtg
    12481 ataccaataa taatgtcaat atactttagt tttacaaagt ataatattat tagtccagct
    12541 acttttatag gtttagaaaa ttataaaaaa ttatttacag atgaaacatt aaaagtatct
    12601 attataaata ctattaaatt tactgttgtt gtagtacctt gccaaactat attatcattg
    12661 attttggctg tttggattac aggaaaagga aatagtaaaa tagcttcatt tgctaaaggt
    12721 gctatattta taccagtatt atcatctatg gttttgatag gtatggtatg gagggcttta
    12781 ttgaatggag aaggttctat tatatatcag gtattaggtg cctttggaat agaatcatct
    12841 aaacttttag gagatagtaa gacagcatta cctacactta tgtttatatc tatgtggaaa
    12901 aatatagggt atttcatggt aatttatatt tcagctataa tgaatttacc aaaacactgc
    12961 tatgaagtag cgaaggttga tggggctaca aaacttcaag aatttataaa aataactgta
    13021 cctttattga aaccaactac aataatggtt gtatttttag ggtcgatatg gtcattacaa
    13081 gtatttgact taatttatac tgtgacaggt ggaggtccag gtatatctac tatgagtata
    13141 gttatgcatg catttaactt aaactttaaa aactttaatt ctggatatgc aatgactgta
    13201 gcaaacgtat tatttttgtt aatagcagta gtttcgattt tacaaaataa gcttgtaaga
    13261 cgagacaatt cagattttta gaaaggtagg tataatatga aaacagcaag aagattatta
    13321 agtgatggtt tacttttatt tatagcgtgt gcaagtttgg taccttttat atacatgttg
    13381 ataatatcat tgaagataac atataactca tatagtttgg atatatcttt ttcaacagta
    13441 acccttcaaa actatataga tatttttact aaaaaaggat ttgcacaata tttttttaat
    13501 acagcaatag tatctttttc aggtgtatta ttaaatttag tatttagtac attagcagga
    13561 tattcttttg cgaagatgga ttttaaaggt agtgataagt tatttttatt tatgataatg
    13621 actttaatta taccttccca agttacaatg ataccactat atataataat gaaacactta
    13681 ggatggataa atagttatct tgcacttatt atgccaatac caactgcatt tggcgtattt
    13741 ataatgagac aagctatttt aggagtacca aaagagttat tagaatcagc aaagatagat
    13801 ggttgctcgg attttagaat tttaatacaa atagtgttgc ctttaattaa accagcatta
    13861 attacactag caatatttac ttttatggga gcatggaacg agtttatgtg gcctcttata
    13921 gctacaacta aagatgcaat gagaacatta acagttggat tatctactct taagacattc
    13981 cagataacta attatggaca gatgatggca ggggctacaa taacattttt acctccattt
    14041 attttctatt tgattttaca gagtaaattt gttgaaggtg tgtctttgtc tggtataaaa
    14101 ggttaaatag tctaatttaa taatatataa agaaacttat ataaatatgg aggaatttaa
    14161 actatggaaa tttcatatgt actgaaagat tgcacattca aacacaataa atactcagtt
    14221 gtagaagctg aaacttggaa agataaggat ttggatattg tagtagctaa aggtgaaaaa
    14281 tttgcatttc aaattatgtt aaaagcaaca gaagaattta attgtacaat tgataaaagt
    14341 agtgctatat catggaaagg cctgggaaat agagtaagat tagcattaaa tgtacctaat
    14401 agtttagaaa ataattttag tataaatata ctaggatatg ttcaagatga tacaaaagca
    14461 tttgtgaatg atgctatttt aagggataaa gatatgttag tagagcaata cttgcctcaa
    14521 acattttggg tcgaaggtca agttccggaa gattttgaag aaaataactt taatataggt
    14581 attgatatat ttaaaagctt tggatatgaa gatgaagaaa aagcttgtac aattgacgtt
    14641 cctgtagaag taaaaaatgt tgtattaaag cctttagatg aaagtaagtt ctttttagat
    14701 ttatggcaac atccaagctg tctagctaga atgtataaag ttgagctatg gtctgatata
    14761 cattttgaaa taatcgataa ctatctaaaa gaattagctt ctttaggaga aaaagttgca
    14821 acaattatag tttcagatta tccatgggca gggcaaagtt gttataaagt ttataaaaat
    14881 ccatcaaact tatatgaata taacatggta agtgtatcaa aaggattgga tggaaagatt
    14941 aaatgtaact ttgagagtat ggataggtat ataagcatag ctgataagta taaaatggct
    15001 aaggagatag atttatttgg tctattaggt aattggtgtg ctggtgagtt tggaaatcct
    15061 gtagaaggtt ataaggaccc tataagagta agatattttg atgaaaagga taaagtattt
    15121 aaatttataa acaatacaaa tgatttaaaa gaatatatag gattagtatt aaatcattta
    15181 atagagtgtg gattatggga cagagtaagg attatagctg atgaaccaaa taatccagaa
    15241 gtagtcaaag agtgtataga atttataaat tctactgtag gtactcatca agttaaatat
    15301 aaatcagcaa ctcacgacca aaacttttta gacagagcta aagatgaaat tgatgatatg
    15361 tcaataaatt taaaacttac tatacaaaat tataaagata tagaaagtct taagaaaaaa
    15421 atcaatgaca agggtgggat attgacttgg tttgtatgct gttttccaga gaaaccaaat
    15481 agttttttaa gttctccttt tgtagaaaat agaataatag gatggtatac ttattacttt
    15541 ggtcttgatg gatttttaag atgggactat aatttatgga cagaagaccc ttggaaagat
    15601 tcaagttaca aattccctat ttggaaagct ggagatatgt tctttgttta tcctggaaaa
    15661 gatttaaagc cagttagaag tgtcagaatg gagaatttaa gatttggaat acaggacttt
    15721 gagttattta caatgttaga aaaagaaaag ggaagagagt atatagaagt tgagcttatg
    15781 caagaattat taaataaaaa agaaaatgct gaaattaaag gttttggtga catagaacta
    15841 ggatattcac ttgataattg gggatatgat aaagttaaaa aatatgtatt agagttgtta
    15901 gacagagtat aaaaaatata agagtgtctc aaaatgaact ttttagttca tgaggcactc
    15961 tttttgtatg aaatcaatat agtttcattg tttcaacaat gaaaaatagg attatttcta
    16021 ttctaagaca gccctttagt tttttagttg tattcaatgt tttaaaacta actataaacg
    16081 ctataaagtt tataaatgac aataattata tataacatga tgtactttaa tttgctataa
    16141 tagggattga ataatattat atggaagata acattgtttg gggggattaa tataaaaaga
    16201 ataggtatta ttataatgtt ttttttaagt atatctttta ttggatttta tcttgtaata
    16261 agagataaca gtgatacagt taagatgcaa cgagggataa atataggtaa tgcactagaa
    16321 tcacctaagg attttccgtg ggatgtaaaa atgtcaaata agttttttga tgatataaaa
    16381 gatgcaggtt ttgacacagt acgtatacca gtaaggtttt ctgattatac gtcagattct
    16441 gataatttta aaattgatga agaatttttt aaaaagattg ataaatatgt agattatgca
    16501 ttggataaag acttaatagt tgtgttggat ttacaccatt ttgaagaaat tatgaaagaa
    16561 ccaagagttc ataaagaaaa gtttttaaaa atatggcaac agatagctaa taggtatcaa
    16621 aaatatgata aaaaattggt atttgaatta ttaaatgaac ctaaagaaaa tttatattca
    16681 cagttactaa acgaatacat tgaagaagca ataaagataa ttagaaaaac taaccccaaa
    16741 agaactatta tagtaggacc atataatttc tatcaaattg attatttgaa tgaattaaat
    16801 attcctaaag attctaatat agtagtttct tttcactatt acgagccaaa tgattttgca
    16861 tttcaaggaa atatctatca taagggattc gagcacttaa gcaatattac ttgggaagga
    16921 acaaatgaac aaatggatta tttaaaaaaa aggtttgata ctgtggaaaa ttgggcaaat
    16981 aaaaataagg taaaaatctt cttgggtgaa tttggaataa caaaagaggc accagaagct
    17041 tcaagaagag catggataaa agctgtaaga gaagaagctg aaaaacgaaa cttttcatgg
    17101 gcttattggg agcttgcatc tggatttggt atatacaatc aaattgaagg gacttgggat
    17161 agagatatat taagtgcatt aatagaaaag aggtgatttt atgaagaaaa attcaaaaaa
    17221 gatacttata actttaacta ttattactaa tgtcatatat atattgtgga gaatttttta
    17281 cacagtacct aaagaagaag ggaagtttgc cttaatatgt gccataatac ttctttttgt
    17341 agagataatg ggcatgatgg aaatgtttgt gcattattat ggtatgtcaa atattgagta
    17401 tcctgaaaaa ccaatcataa gtgaagaact ttatccacat gtagatgtat ttattgcaac
    17461 atataatgaa tctgttgatt tggttagaaa aactgtaaat ggatgtattc atatgcagta
    17521 tccagataag aaaaaggtac atatatacat atgtgatgat ggaaatcgtg aagaaatgcg
    17581 tattctagca gaaaaaatgg gtgtaaatta cataactaga actgaaagag aaggagcaaa
    17641 agctggaaat ttaaataatg caatgcaaca tacaaattcc cctttgattg ctacatttga
    17701 tgcagatatg ataccaatgc atgacttttt aattgctaca gtaccatact ttttgaaaaa
    17761 tgagcaagct aaaaaagatg gagaaaaaga ggagtatgaa aaggttggtt ttgtgcaaac
    17821 tccacagagt ttttataatc cagatttgtt ccaatttaat ctgcactctg aaggaaggat
    17881 tccaaatgag caagattatt tttacagaga tattcaattg gctagaaata ggacaaattc
    17941 tgtaatttat ggtggtagta atacagttat ttcaagggaa gcacttgaag aagttgatgg
    18001 attttatact tattctatta cagaagattt tgcaacaggt atcttaattc aaagtaaggg
    18061 gtatagatgt tatgctattc cagaagtaca tgcatcaggt ttatctccga cagatttaaa
    18121 aagtcttatt aagcaacgtg aaagatgggc acgtggatgt atacaaactg gtagacgtct
    18181 aaatattttg tttaggagag gtttaggttt ttggcagaaa ataagttata tttcttcaat
    18241 tacttattgg tatgcaagta taaaacgctt tgtatatata atggcaccta ttttattttc
    18301 tgtgtttaat gtgattgtag taaaatgtac gttacttcaa gtattggtat tttggttgcc
    18361 aatgtatatt ttaagtagtt tatctcttaa aatattttct caaaatataa gaaatactag
    18421 atggaccaat atatatgaaa ctataatgtt tcagtcttta atgccagcag taatacttga
    18481 aacgtttgca atatctaaaa ataaattttc agtaacaaat aagagtaaat tagaagaaaa
    18541 tagaatgtat aagtttttac agggaatacc ttattttatt tacatggtct tatctatcat
    18601 aggaatttta aaaatgtttg tagcaatatt taaaatgagt tcaatgacat attcagttgt
    18661 attattttgg ttgattggaa acctttttaa ccttgttatg gctacattat ttatatcagg
    18721 gagacagcag ttaagaaagt ctgagcgtta tattgctgaa attgatttta agttaaagca
    18781 aaattcttat gttctttctt caaaaacaat tgatatatca gaaaatgggt ttgcattttt
    18841 gctagaaaat ccagaatata tttccccaga agaagagttt gaggtagagt ttagagaaaa
    18901 atctggaaat gaaatgtata tagctaatat gaaagcaaag attgttaatg ttgtggaagt
    18961 aaattcaaag tggaaatatg cagcttatat tacacatatt gaggatagtg aaatagataa
    19021 ttggatgtgt attgttcacg atagaatacc tactttacca atgacaatat ctaatcaact
    19081 aggtttcttt gatgatttgc aaattaatgt aaaaaaacgt attgaaaaaa ctagaacatt
    19141 atcacgaaga agtccaagaa tcaatatgaa ttttcagatg gatataaaaa atacaggtaa
    19201 attaagaata gtgaatttta attatcaata tgtattatta aattttgaga ataaaagtat
    19261 ttatcctaaa gaaatagcat tggaaattaa tgaaaatatt gtgttagaat gtgatttgtg
    19321 tgagggtaaa attgatgaaa gaggtatctt atataaagta aataacattg acagcataat
    19381 gcaaaatttc tttttaagag atgaaatgat ggattggata ttacaaaata agacaattct
    19441 tgtttcaaag cctagtgaaa agaaggaaaa aagtatagat gagtttgaac ccatggaata
    19501 tatttaggag agatgaaatg aagactttaa aagtgttttt ttgttctaca aaatatctta
    19561 ttttggtgtt tatttttttt ataaatacta cttttataag ttcagcaaca agtgataaaa
    19621 ttttagattt atcctttaaa aagatagaga ctgacttaag ttctaagatt acatatgagg
    19681 atacaggtgt aagaatagaa acggatagtt ctaaaagcga taaggaacgt tatttatata
    19741 tttaccaaaa tataaaagaa aattggagca tgtataataa tttttatatt gaaattcaaa
    19801 ataaaaataa aagttctcag agaataaatt taagcataca aagtaaaaat atgcttgaat
    19861 ttagattaaa agaaggtagt gaagtatttt tagaaggtaa aaatataata tattcagata
    19921 aaataaaaga aggatgcata gaagtactag gtgaatttga aggcaaaatt tatgtgaact
    19981 ttaatagcct tataaatgag gaaagtaatg ttgtgctgga ctcaaatatg ctttcaaaca
    20041 ttgttagttg gggaattacg tttattccat ctgatgaaga acataatatt gttattataa
    20101 aaaagatatc tttattgtct gaagagaaat taagattttt aaataatatt aaaataattg
    20161 gcgatgaaga agtacaaata ccagtattgg gtcaaagtat aagtcagtat gaagtattag
    20221 gtcttaaaag tgattctaaa attaagtact ctcttatggg aaaacaagat aatgtgagca
    20281 tatctcaaaa aggtaaatta acattaagta ataaagccaa acctggacaa attattttac
    20341 aagttaatgt tgatgataag tttaaaattg gaaagaaaat aacattaact gagtcttgga
    20401 gtgttaataa aaaagataag gatggtgttc catatacatt agtatatcct gagcaatcac
    20461 caacagtaca agatatgaaa aaaataaact ttatgaataa catcataacg tttgttcgaa
    20521 ttttatttgt atctctagta ataatatgct ttggaatata tttatattgg aaaaaatgtt
    20581 caaaaactaa gtaaagagag gaggttagat tgtgttattt tcaagtttaa tttttttatt
    20641 ttatttttta cctataactt tggttttata ttatgtattt aggtttaacc gaacgataca
    20701 gaacatgata ttgcttgctg ttagtttatt tttttatgct tggggagagc caaaatttgt
    20761 tgttatcatg atagtttcca taataatgaa ctatatattt ggtttactgg tagatagata
    20821 tagggaaagt aaaataaaag taaaagtttt tttagttttg atgtgtgcat acaatatagg
    20881 tgttttattt atatttaaat atctagcttt tgcgctaaga aatattagtg aacttattag
    20941 tactgaattg actataccta gtattgtttt acccatagga atttcatttt ttacatttca
    21001 gggaatgtct tatgttatag atgtatatcg tagacatgga gaagtccaaa agaacccttt
    21061 ttatgtggga ttgtatatag catttttccc acaattaata gcaggtccta tagttagata
    21121 tgagagtgtg gcagaacaaa ttctcaatag aaaagaaact tggaataaat tttctattgg
    21181 gacttgtagg tttataacag gtctaggtaa aaaagtatta atttcaaata acatggctat
    21241 agtagcagac tatatttaca ctatgaatag tcaaggagaa atagctgcat cacttgcatg
    21301 gcttggttca atagcctata ctctgcaaat attctttgat ttttctgctt attcagatat
    21361 ggctataggc ttaggtctta tgtttggttt taaatttgaa gagaacttta attatccata
    21421 tatatcaaaa tcaattagtg agttttggag aagatggcac atttctttgg gaatgtggtt
    21481 taagagctat atatactttc cgcttggagg ttctagagta gcaaataaag atattatgat
    21541 tagaaatatg tttatagtgt ggttattcac tggaatatgg catggagcag aatggacatt
    21601 tgtaatttgg gggattttaa actttgtttt cctaattata gagcgattta taatgtttga
    21661 aaagattgaa aatcacaatt ttataaaaca tatttatgct ttattagtag ttaattttgg
    21721 atgggtattg tttaggtcac ctaatttaaa agaagcatat aattatttta aagctatgtt
    21781 tggaggcaat ggagctatat ggagtgatta tacatatatg tttttaaaag aatactgggt
    21841 tttctttata tttgcattta tttttagtgt acctattgca aagaaaatca ataagtttgt
    21901 tgttgaacaa gctaaatata gtatgatatt taacgtattt tatccaatct cagctatttt
    21961 attgtttttt atttctgtga catatttagt aactggaagc tataatccat ttatttattt
    22021 taatttttag ttgggaggaa aagtatgaat agatttttta aagtaagatt aataactgca
    22081 attatgttct taattatttt attcgctttc tctatcttta atgtttgtta ttctggaaaa
    22141 gatacgatac aggaaataaa aaattcaata gctgaaaaaa gtagtttaaa agatacaata
    22201 tcatctattg ataatacagt gaatgacaaa gtaatataca aaaatacgtt cattgaaact
    22261 tatggctatt tacaaaaatt aatgggtaaa aatgagtttt caaaatttag tgttgtaaaa
    22321 gatacttctg gaaagatgca ttatacatat tttgctaaag ctccaaatcc agttggtgtg
    22381 atagcagata gggtaagaaa attttctgat gaaatggaaa agcaaaacac taaattggtt
    22441 tacctaatga ctccagataa gtatataaaa ggagtgacaa aatttccaaa aggaatacct
    22501 tattcttata gtaatgagac agcagataat tttttaaatc aactaaaaaa gtataatgtg
    22561 gactatattg attttagaga aaatatttta aagagtggta ttccaaaaga tgatttattt
    22621 tttaaaacag accatcactg gaaagtagaa acttcttttt gggcatttgg agaattagtt
    22681 gagcaactta ataaaaaata caatatgaat ttagatgaaa atcattatta tagagataag
    22741 gacaattata attcaattgt atatcctaag tcatttcttg gttctatggg aagaaagact
    22801 ggtatcttat atggtggtat agatgatttt acattaattt atcctaaatt taagactaat
    22861 tatacttatt atacagattc taaatctcaa aaatttgaat taaaaggaag gtttgaagag
    22921 agtttaatat tatcatatcc ttttaatgca gaccttgatt taatggatgg tcaatcagat
    22981 aagtatttta catatttatt ggggaacaga ccattagtta aaataaaaaa tatagaaaat
    23041 ccagatggat taaaagtgct gtttgttaaa gattctctaa ttgtaccaac agcagcattt
    23101 ttttcctctg tttgttcatc tatagatatg atagacccta gatattatga tggagatata
    23161 ttagaatatg caaaatccca tgactatgac tttgttttta tatctgtata tccccaaaat
    23221 cttacaaaag aattttttcc gttttgtaag taaatttcta aagaaatttt cttataaaat
    23281 aaaaaataaa tggctaactg gttaaaagtt agccatttat tttaagtgtt actctaagaa
    23341 atattttttt tactaaatat ttctttatct atttttccaa gtgattttcc tacagtaatt
    23401 gatgatacca tagcaccatt aacatttatc atggtacgtc ccatatctag tatagggtct
    23461 attgcaagta taccaccaac taatggaaaa taagaaccaa gaccaactcc agagataaca
    23521 actgaaacgg ccattgtagc agttcctgga agcccagcta ttccaaacga actaattgtt
    23581 ataacaatta acaacataac ataaaagctc atatccatgt ttactccagc catattggca
    23641 agtgttacag ccattaaagc aggatatata cctgcacaac cattcatacc catatttgca
    23701 cctaaacttg ctgtaaagct tgatacaccc tcatcaactc cgtgattttg tactagactt
    23761 tctatcgtta caggcaatgt tcctaaacta gaacgtgaag taaatgccag aagtaaagct
    23821 tcagttgaat tttttatata agtaatggga tttagaccat ttaaagttat aaaaattaaa
    23881 tgtataataa ataatattgc aactgatata taaagagcta atataaactg taaaacagat
    23941 actattgaac taataccttg tgaagttatt gtatttgcaa gcagagcaac cacagcataa
    24001 ggcataaatt taataacagt catagacaca cttacaatta ttttgtaaga tgcttctata
    24061 aaatctataa atggttttat tgtttcaaaa tgttttttac ttaatctctt tattgaggta
    24121 gctataaatg tagcaaatat tattgtagct acaatatttc catttgccat agccattaca
    24181 ggattagatg gtagtaatcc tcttaaagta tccacaagag agtttatttc tttaagttct
    24241 tgattttcaa ctaaagtagg catattagct cctacaccta acttcattat atttgcaacg
    24301 ataattccaa caattgcagc tatagcagta gtagcaagaa gcatacctaa agatttaaat
    24361 gtcagagttc caagattgtt atctttcata tttataatta cttttataat ggataagaaa
    24421 actaaaggta ctactaacat ttttaataag tccataaatc cagaaccaaa taggctatac
    24481 cacttactta cttcttgtag ccaagtgact tgagttgtat cattaggaaa accggcaaaa
    24541 gcttgtatta tgattcccaa tatgagtcct agtactgtag catatattgt tctcaatgaa
    24601 aattttattt ttttcttttc aaattgtcta acaataaaga acgtacctag aagtaatatt
    24661 atgaaaaaaa ttgttttaaa atctgtaatc ataagaaatt gtgataaaaa tgaactttcc
    24721 aatatttttc tccttttatt taaaaataaa tttttctaag tttaaatgat atcaatatat
    24781 taaaaaaatg tcaatattat atcacaattt acttaaatag agtaaaacaa gttgattttg
    24841 aaaaatgtga ttaagtatag aaaaataggg tataataaat gtttaaagaa tttgaattat
    24901 ggtaagaaaa taaaaaatag cttttataag atttgatttc aaattaaaat atgttaaata
    24961 aataactaaa aattgttata aaaaatgttt tcatagaata tatatcaaat gaaaagctta
    25021 aaataagtga agaaattaac tagacatcaa aggagagata aaatgagagt aataataatt
    25081 ggtggtgttg cagctggtat gagtgctgca gcaaaattaa aaagaataaa acctgagtat
    25141 gaagttgttg tttatgaaaa aactgaaata gtatcttttg gtgcttgtgg attaccatac
    25201 tttgttggtg gattttttaa tgatgctgat gaattattag caagaacacc agagaaactt
    25261 agagaagctg gaattgattt aaatatattt agagaagtcg ttgaggttga tagtgaatct
    25321 aagaaaataa aagtaaaaaa cataaaaaca gatgaaatat atgaagatta ctatgataaa
    25381 ttgatgatag caactggagc aagaagtatt atgcctccta taaaaaacat aaaattgaag
    25441 aatgtatcta cattaaaaag tttatatgat ggagaatatc taaaaaaact tttaagtaat
    25501 gaagataata aaagagtgac aataatagga gctggtttta tagggttaga agcagttgag
    25561 gcatgtaaga aattaggtaa agatgtagat gtaattcagt tagaagatag aatattgcca
    25621 caagtatttg ataaggagat gacggatgta ttagaagaag aaataaatag acataatgtt
    25681 aatttgcact tagatgaaat ggttgtagaa ctttgtggag aagataaagt agaaaaagtt
    25741 ataacaaaca aaggggaaat agatacagat gtagtaataa ttgctactgg cgtgagacct
    25801 aataccgagt ttttgtcaaa tactaatata aaaatgctaa aaaatggagc tatagtagtt
    25861 gatgagtatg gaagaacttc tgtagaagat atatactctg ctggagattg tgcaactata
    25921 aagaatatag taagtaatga aaatgtatat gttcctttag ctactggagc taataaattg
    25981 ggtaggatag taggagaaaa cctagcagga agagaagtat cttatcaagg ttcactatct
    26041 tcaagttgta taaaaattat ggatatggag gcagcatcaa ctggaattac agaaaggcaa
    26101 gctaaagatt taggcataaa tgtcaaatct aaatttattt ctgattataa tcaaactcat
    26161 tattatccag gaagaaataa aatatatgta aagcttattt atgatgcaga tacaaaagtt
    26221 attttaggcg gacaagtggc tgggtttaag gatgctgtcc aaagagcaaa tgtattggca
    26281 gctgctatct ttggaaaaat gaccacaagt caacttggaa tgttagattt atgttatgct
    26341 ccaccatttg caagaacatg ggatgtttta aatgtagctg gaaatgtatc taaataatat
    26401 ttagattata gctaatatag ttgacaagca attaagggaa tgaatttacc taaactattt
    26461 ttataatggt aaaattcatt cctaaatttt tattccaaat ttttagaaat aaggcttcta
    26521 ttaaattatt catcaaaatt taaacgcaag cttaatctat cttctccaag aatagtattt
    26581 tcaaaaacat tagtagcatt ttctaaatac atactaggta tgtctaaaga aggactaaaa
    26641 tgagtcagta aaagttgttt gacatttcca agttttgcaa gattagcagc ttctctaaaa
    26701 gtcatatgtt tgtttctaac agcttttgat atatctaaat catcaccata catggcttca
    26761 catataaata aatcactatc ttttatgaaa tctggtattg attctatagg tcttgtatcg
    26821 gttgtaagac ttatcttaac tccctttctc aattctccta agaccatatc tggagtgtat
    26881 tgttttgaat ctaaaactat attttgacct tcttggagtt tgttccataa tattttagga
    26941 acttcgtttt tagttgcctt atctatatca aatttagggt ttcttctaaa attaaaactg
    27001 tatcctaaac actctataga gtgttctaaa ctgattgttg aaatttctaa atttcttaaa
    27061 actttattat ctaaagaaaa attgccttga gggttttcta taatttttaa agtgtatggt
    27121 acatattcta ctaaatttct catagaacgt atacaatcga ctattccaac tggaccaact
    27181 atagttaaat cacttgtacg accactattt ccaattgttg ataaaagtcc taaaagtcca
    27241 aatatatggt caccatgtaa atgggttata caaatcaagt ctatatcttt aaagccacat
    27301 ttttttagct tcatagatac ctgagtacct tcaccacagt caattagtat ttttctacct
    27361 ttatagttta taaatacaga ggatagaaat ctgtttggca taggtacatt tccaccacat
    27421 ccaagtaaag ttaaatctat cattttttcc cctttctaaa attaacacaa atctgttgtt
    27481 tgtttttatt atgatatcct attataatta ttttaacatt aaatataaca ataaatgtgt
    27541 atttgagtca agaaatattg tcaaataaag tttttatata gaaatgtata aaaatttgga
    27601 aaacaaaaag tgaaaattat atttaggagc atttaaagga ggaaaattta atgaaagtat
    27661 taaagaaaat tactattttg tcattgatta cattaacctt agttggttgt agtaacggag
    27721 aagataaaaa agtggttgaa ggttctaaga aaattcaaaa ttctaaaaaa gatgaacagc
    27781 ctataatagt acataaagat gcaaatatat tgaaagatag gtatgagcca ccaaaaggat
    27841 ttaaaagagt tgatgtagaa aaaggtagtt ttgaatcatt tcttaggaat actaagctaa
    27901 aaaattatgg agagaaagta aagtattatg atggaagaac taaggaatca aaaggtattt
    27961 atgatagtgt atttgatgtt gatattggca atagagattt gcatcaatgt gcagatgcaa
    28021 ttatgcttat gagagcagaa tacttgtatc agaataaact atatgatgaa ataagttttg
    28081 attttgttga tggttttaag gcgaagtatt caaaatgggc acaaggatat agaatttcag
    28141 taaaagatag tggttcaagc tggtataaag caactgaata ttcaacatct tatgagagtt
    28201 ttagaaagtt tatggatata gtgtttgcat attcaggaac gttatctctt gaaaaagaat
    28261 tggagcctgt aaaagttgag gatatgaaaa taggagatgt gtttatagtt ggtggaagtc
    28321 caggacatgc aagtataatt atggatatgg cagaaaatga aaagactggt gaaaaggtat
    28381 ttatgatagc ccaaagctat atgcctgcac aacaaacgca acttcttatt aatcgtaaaa
    28441 atccaaattt gagtccttgg tatagtttag attttgaagg tgatttgaca atacctcaat
    28501 ggacttttaa aagagaccag ttgaaaagat
//
LOCUS       DAEPUT010000047        28100 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.049, whole genome shotgun sequence.
ACCESSION   DAEPUT010000047 DAEPUT010000000
VERSION     DAEPUT010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28100
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.049"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     regulatory      <1..72
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            477..794
                     /gene="flgB"
                     /locus_tag="KRL22_002262"
     CDS             477..794
                     /gene="flgB"
                     /locus_tag="KRL22_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBH1272750.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            802..1206
                     /gene="flgC"
                     /locus_tag="KRL22_002263"
     CDS             802..1206
                     /gene="flgC"
                     /locus_tag="KRL22_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBH1272751.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            1216..1533
                     /gene="fliE"
                     /locus_tag="KRL22_002264"
     CDS             1216..1533
                     /gene="fliE"
                     /locus_tag="KRL22_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBH1272752.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            1558..3108
                     /gene="fliF"
                     /locus_tag="KRL22_002265"
     CDS             1558..3108
                     /gene="fliF"
                     /locus_tag="KRL22_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBH1272753.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            3121..4191
                     /gene="fliG"
                     /locus_tag="KRL22_002266"
     CDS             3121..4191
                     /gene="fliG"
                     /locus_tag="KRL22_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBH1272754.1"
                     /translation="MSTEITNVNAFDLSDISESDKNEKIEGEGLKKAAVLLMTLGPDV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNAKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAIRISSMGSISPEVIKVIESSLEDKLHSISGDDFKDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDAISDAIYRNQSSRAAEALREEMEMVGVIKVTQVEAAQQKIVNS
                     VRKLEREGAITIVRNFGDDFVE"
     gene            4175..4915
                     /locus_tag="KRL22_002267"
     CDS             4175..4915
                     /locus_tag="KRL22_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBH1272755.1"
                     /translation="MTLLNNKIIKSKKASYKGVLDLSIIDKVRVGESNLNKENDCRFR
                     DEVIKEAIESAEIKKNEILEEAKINAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYT
                     QKAKDEADFIKNQANLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESM
                     SDLLKQIIQDYEGSSSFIVRCNSFYKDNIEKEFKLFKEETSLKSSVFVIADDSIDKGN
                     AIIQKENGRIIVGIDCAMEKLKEELLGE"
     gene            4919..6238
                     /gene="fliI"
                     /locus_tag="KRL22_002268"
     CDS             4919..6238
                     /gene="fliI"
                     /locus_tag="KRL22_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HBH1272756.1"
                     /translation="MYKTDIYIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRVFE"
     gene            6269..6715
                     /gene="fliJ"
                     /locus_tag="KRL22_002269"
     CDS             6269..6715
                     /gene="fliJ"
                     /locus_tag="KRL22_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HBH1272757.1"
                     /translation="MELDKNFKFRLQKVLDLKVKDEEEIKMEFDKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDSIQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEENLKEQNTNDEFASMSYLRNRQVL"
     gene            6744..7945
                     /locus_tag="KRL22_002270"
                     /pseudo
     CDS             6744..7945
                     /locus_tag="KRL22_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
     gene            7963..8571
                     /locus_tag="KRL22_002271"
     CDS             7963..8571
                     /locus_tag="KRL22_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HBH1272758.1"
                     /translation="MYGIATALAGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEQESPEEA"
     gene            8598..9581
                     /locus_tag="KRL22_002272"
     CDS             8598..9581
                     /locus_tag="KRL22_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HBH1272759.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQIYAFQNPAGLDAAGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            9594..9797
                     /locus_tag="KRL22_002273"
     CDS             9594..9797
                     /locus_tag="KRL22_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HBH1272760.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            9797..10615
                     /locus_tag="KRL22_002274"
     CDS             9797..10615
                     /locus_tag="KRL22_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HBH1272761.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            10605..11300
                     /locus_tag="KRL22_002275"
     CDS             10605..11300
                     /locus_tag="KRL22_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH1272762.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIDSVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKVDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            11312..11755
                     /locus_tag="KRL22_002276"
     CDS             11312..11755
                     /locus_tag="KRL22_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HBH1272763.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            11770..12144
                     /locus_tag="KRL22_002277"
     CDS             11770..12144
                     /locus_tag="KRL22_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HBH1272764.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            12145..12810
                     /gene="fliP"
                     /locus_tag="KRL22_002278"
     CDS             12145..12810
                     /gene="fliP"
                     /locus_tag="KRL22_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBH1272765.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGSQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            12823..13092
                     /gene="fliQ"
                     /locus_tag="KRL22_002279"
     CDS             12823..13092
                     /gene="fliQ"
                     /locus_tag="KRL22_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBH1272766.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            13104..14918
                     /locus_tag="KRL22_002280"
     CDS             13104..14918
                     /locus_tag="KRL22_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HBH1272767.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGVNETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSADKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            14927..17002
                     /gene="flhA"
                     /locus_tag="KRL22_002281"
     CDS             14927..17002
                     /gene="flhA"
                     /locus_tag="KRL22_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBH1272768.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELISNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMSNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            16977..17993
                     /gene="flhF"
                     /locus_tag="KRL22_002282"
     CDS             16977..17993
                     /gene="flhF"
                     /locus_tag="KRL22_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HBH1272769.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            17990..18868
                     /locus_tag="KRL22_002283"
     CDS             17990..18868
                     /locus_tag="KRL22_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HBH1272770.1"
                     /translation="MIDQAQILRKIAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            18882..19583
                     /locus_tag="KRL22_002284"
     CDS             18882..19583
                     /locus_tag="KRL22_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HBH1272771.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            19599..20021
                     /locus_tag="KRL22_002285"
     CDS             19599..20021
                     /locus_tag="KRL22_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH1272772.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRINSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            20006..20191
                     /locus_tag="KRL22_002286"
     CDS             20006..20191
                     /locus_tag="KRL22_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH1272773.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            20232..21005
                     /gene="flgG"
                     /locus_tag="KRL22_002287"
     CDS             20232..21005
                     /gene="flgG"
                     /locus_tag="KRL22_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH1272774.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            21026..21787
                     /gene="flgG"
                     /locus_tag="KRL22_002288"
     CDS             21026..21787
                     /gene="flgG"
                     /locus_tag="KRL22_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH1272775.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            21810..22691
                     /locus_tag="KRL22_002289"
     CDS             21810..22691
                     /locus_tag="KRL22_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH1272776.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            22694..23068
                     /locus_tag="KRL22_002290"
     CDS             22694..23068
                     /locus_tag="KRL22_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH1272777.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            23100..24503
                     /locus_tag="KRL22_002291"
     CDS             23100..24503
                     /locus_tag="KRL22_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1272778.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNNVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVKN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            24619..26556
                     /gene="htpG"
                     /locus_tag="KRL22_002292"
     CDS             24619..26556
                     /gene="htpG"
                     /locus_tag="KRL22_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBH1272779.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYISDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEVVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            26944..28074
                     /locus_tag="KRL22_002293"
     CDS             26944..28074
                     /locus_tag="KRL22_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH1272780.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
BASE COUNT        11609 a         2974 c         5224 g         8293 t
ORIGIN      
        1 agagaaatct agtgacgcaa agctataggg actaaggttt atatacataa actatgtcag
       61 ccagttgcca aaaagagtcc taggtgtatt gtatacctaa gaaaagtcta taatgactgc
      121 ctttttggca gtcattttgt tatggaaaaa tcactttatt tcagtagaaa atacatataa
      181 taacatattt taccaattat aacataaaat aaagaaaaat tatctcaaaa agttactatt
      241 ttacaaaaat gacttcttta tttatttaaa ttaatcgcat ttccattaca ttaatacaat
      301 aatgtatcaa tttagtaaga aaactaatat ttttttaatg aagtcccatg aaaatataaa
      361 aaaattttaa tatgtattta aatatttctt cgaaaagttg ctctttttgt aatatagcaa
      421 cttcattttt tattaataaa caaaatagat aaaatatatt ttgaggaggg gtgagtgtga
      481 atacatatga cattataaaa atgggattag atgcaactaa tctaagaagt cagacaatag
      541 caaataatat agcaaatata aatactgaag gatataaaag acattatata acttttgaag
      601 aaacactaaa tgatgctatg cctaaaatag aagaaaaaac agacaattct aaaggtttaa
      661 gagtagatgg taataatgta gacatagaag aagaaaaagt aaatcaagca atggcaacat
      721 tacaatataa tgctttgata agttttgcaa atggaaaaat agcaatgacc aaatcaataa
      781 taagtgggag gtaattagaa gatgagtgtg ttcagtggaa tgagaatatc tgctagtgga
      841 ttaacagcag aaagtttgaa aatggatatc atatcatcca atgtagctaa tataaatgct
      901 acaagaggtc caaatggaga agcatatagg agaaaagttg tttcatttga agaaaactat
      961 gataataaat taggtatgct aggagtaaaa gttacatctg ttgaagatga taaatcacct
     1021 cttaaagaag tatatgaccc atctcatcca gatgcaaagc caaatggata tgtagaatat
     1081 ccaaatgtaa atatattggt agaaatgaca gatttaataa cagcttcacg agcatatgat
     1141 tctaacgtag atacattgaa tgctcagaag tctatgatat caaaagcttt ggaaatagga
     1201 aagtagggat aaattatgcc aattacacaa attaacaatt taatgcaagg tgcaaagtta
     1261 gataatttga ttggagaagc aaagccatta actcttaata ataaagaaga aaaaaagaat
     1321 tttgaagatg taataataga tactatagat aaagttaatt ttcaacaagt aacagcagat
     1381 gatatgaaag aaaaatttat aaaaggcgaa gatgtttcta tgcatgaagt tatgttaata
     1441 ggtcaagaag cacaactatc tatgcaatat ttaatagaag ttagaaataa gattcatgat
     1501 gcatatcaag aaatgaataa ggtgcaaatt tagccttttg aacaggagta ataatcaatg
     1561 ataaccagtt ttaaaaataa gattaaggag caagttgcta aatctaggac aaagataagt
     1621 tctttaaaaa agggaactaa aatagcatta ggtatagggg ttattgctat atgtttagcg
     1681 ctagtattta cagcaatatc tgcgagcaaa aataagtatg cagtcttatt ttcagaacta
     1741 gatgctcaag atgctgcaga tatatcagca gagctagagt ctaaaaagat agatactaag
     1801 gtaaaaggaa gtacgattta tgtacctaga acagaagttg ataagttaag gctggagtta
     1861 gcgccaagtc ttacaggtgg ttctaaagga tttgcactaa tggatgatag ttcatcaata
     1921 gggcttactg atgaagaatt tcagattaag aaacaaagaa tgatacaagg tgaaatagaa
     1981 aaaacaataa agagttttcc acaagtggaa gacactagag tacatataac atttggagag
     2041 tcatcagtat ttgagaagga ggctgttcca gggagtgcag cagtttattt gatgctaaaa
     2101 ccagggacga ctttagaaaa aaaccaaata aagtctgtta tggcacttat atcaggaagc
     2161 gttacaaata taccagagaa aaatgttcag gttattgata acaaaatgaa tttattatct
     2221 gaaggtattt tggaggatga aaatgttgat gaaaataatc aaccaataaa tagtggcatt
     2281 agtgttgata aaaataaggc atctgaacaa gcattgaata aacaactaga aaagtctatt
     2341 ttagaaatgc tagaaccgat atttggtaag ggaaaggtga aagctacagt aaatgctgat
     2401 ttaagttttg atacagctga aaaaactgag ataaaaattg accctgataa agttgcaata
     2461 aaggagacaa ggtcgaaaaa ttcatctaaa tctgctgcaa ataatgttca aggtgtagat
     2521 gctaacatga ataaccaagg aaataacaat ggtactaata cagaagatag tttagatgag
     2581 agttttgagt atgaaacagg taagattgaa actcacacta tagttgcgcc tggagaactt
     2641 aatagattga cagcttctgt tgcaatagat ggaaaaatag ctaaaggtgt tcaagctgat
     2701 gtagaggata ttgttaataa tgctataggt atggatggag cgaggggaga tactcttagc
     2761 gttgtttcaa tggtatttga cccagaaggt aagaaagagg ctaaacaaga gctggaagag
     2821 attaaaaaag aaggatttaa aaagaacata ataaaagcag ttattggagt agtagcagta
     2881 atagcagttg gagctattgg atacttaata tataagaaaa gaagtgaacg agaagatatg
     2941 gattatgaag atgaagatta tatttccaaa tctgattctg ttgataggaa agataatcct
     3001 ctattaggag atgacccaga actgacatta gaggaagctg ttaaaatgta tgcagaagaa
     3061 aagccagacc aagtaacaga gataataaaa acttggttaa atgagtaagg gggatagaaa
     3121 gtgtccacag aaattacaaa tgttaatgcg tttgacttaa gtgatataag tgaaagtgat
     3181 aagaacgaga aaatagaagg tgaaggttta aaaaaagctg ctgtattatt aatgacatta
     3241 gggccagatg tctctagcga tataataaaa agtttgcctg ataaacaagt tcaaaaaata
     3301 ggtttggaaa ttgcaaatat ttcttcaata gcttctaaag aaagaagaga aatcttaaaa
     3361 gagtttgtag aaataaatag agcaaaagat tatgttatag aaggtgggct tgaatatgca
     3421 agagagttat taagtaatgc tttgggaaat gctaaagcaa acaaattact tgaaggtata
     3481 tcaataaata caagtacaaa gccttttaaa catattatca aactagatgt aaagaagata
     3541 ttagaaatac ttaggaatga aagtgcacaa actatagccg ttttacttgc acatatggaa
     3601 ccagaaaatg gggcagaagt tttatcatat ttagactttg atttacaaaa tgaagtagct
     3661 attagaataa gttcaatggg ttcaatatct ccagaagtaa taaaggtaat tgaaagttca
     3721 ttagaagata aattacattc aataagtggt gatgatttta aggattatgg aggagtgtct
     3781 accttagttc aaatattgat taattctgat agaaaaacag aaaagaatat cttgggaact
     3841 attgaagaac aaaacccaga tttagcagct caaattaaat ctcatatatt tgtctttgaa
     3901 gatattgtca agttagatga tataagcata caaaaagtgt taaaagaagt aactatgaaa
     3961 gatttagtat atgccttaaa aggtgtggat gatgcgattt cagatgctat atatagaaat
     4021 caatcttcta gggcagcaga ggcacttaga gaagaaatgg aaatggttgg tgttataaag
     4081 gttacacagg ttgaggctgc tcaacaaaaa atagtaaata gtgtaagaaa acttgaaaga
     4141 gaaggtgcca taactattgt aaggaatttt ggtgatgact ttgttgaata ataagattat
     4201 taaaagtaaa aaagcatcat ataaaggagt tttagattta tccataatag ataaagttag
     4261 agtgggagaa tcaaatctaa ataaagaaaa tgattgtaga tttagggatg aggtaataaa
     4321 ggaagctata gaatctgcag agataaaaaa gaatgagata ttagaagaag caaaaataaa
     4381 tgcacaaaat atagaaaagc aagcatatga aaaagggtat agtcaaggtc aaaaaaatgg
     4441 atatgaggat ggatataaag agtcatatga tgaatatacc caaaaagcta aagatgaagc
     4501 agattttata aaaaatcagg caaatttaat cttattacaa gctaatgaga agatgactga
     4561 gtacataaaa gaaaaaaata aagagattgt aagacttgct attaatatgg ccagttctgt
     4621 tttaaaaaag catttcgaag atgaagaatc tatgagtgat ttgttaaagc aaattattca
     4681 agattatgaa ggaagtagtt catttatagt aagatgtaat tctttctata aagataatat
     4741 agagaaagaa tttaaattat ttaaagagga aacatcacta aaatcaagtg tatttgttat
     4801 tgcagatgat agtatagata aaggaaatgc tattatccaa aaggaaaatg gaagaataat
     4861 agttggtatt gattgtgcta tggaaaaact aaaagaagaa ttgcttggtg aataaagtat
     4921 gtataaaact gatatatata tagattttga caaaataaat aagaaaatag aaaatttaga
     4981 actcactata tcagaaggta gagtaaagaa gataatagga cttactgtag aagttgaagg
     5041 aataaaagct tttgttgggg agttatgcgt tatatacaac caagttaata aaccagtgaa
     5101 ttgtgaagta gtaggtttta aagataaaga agtcatatta atggcgttgg gagaattaac
     5161 attgatagca cctggttgta aagttatttc taaggggata cctttaagtg ttatgtgtag
     5221 tgataattta ctaggtaaag tacttgatgg tcttggaaat cctatagaca actcagatgc
     5281 tgttttagga gatagataca acctgaacaa tgaacctcct gacccaatga agagaaaaaa
     5341 gatacgaaat ataatggaaa caggtgtaag agcaatagat gcatttacta cttgtggtga
     5401 aggacagaga atcggcatat ttgcaggaag tggagtaggt aagagtacga ctctaggtat
     5461 gattgctagg aatgcaaaag cagatgtaaa tgtaattgct cttattggag aaagaggaag
     5521 agaagtacta gattttattg ataaagattt aggtgaagag ggaatgaaaa aatctgttgt
     5581 tgtgtgtgca acatcagata aagcccctct agttaggtta aaaggtgctc ttactgctac
     5641 tgcaatagca gaatatttta gagaccaagg caaaaaagta atacttatga tggattcagt
     5701 aactagattt gctatggcac aaagagaagt tggtgtagca ataggagagc caccagctca
     5761 aaaaggatat acaccatctg tatttgcaat gttgccaaaa cttatggaga gaacagggac
     5821 atcagataaa ggttctataa ctgcatttta tacagtatta gttgatggag atgactttaa
     5881 tgagccaata gcagatacaa caagagggat acttgatggt catatagttt tatctagaga
     5941 cttggcaaat aagaatcact atccttctat agatgtatta aacagtttaa gtaggcttat
     6001 gaatgaaatt gcttcaaaag aagacataaa aatagcgtct tttgcaagag acatgcttgc
     6061 tgagtataga gaagcagaag atttgataaa tataggtgca tatgcttcag gtacaaataa
     6121 aaaaatagat gaagcaatct attatcatga gcatattatt aattttttaa aacaagggat
     6181 aaatgaaaag agttctttta atgaaactat aagtagtttg agaagagttt ttgaataaac
     6241 aattaaaaaa atatttgaat aggttgtgat ggaattggat aaaaacttta agtttagatt
     6301 acagaaagtt ttagacttaa aagtgaaaga tgaagaagag ataaaaatgg aatttgataa
     6361 gattcaacaa aaaaaaatag atatagagac taatttagaa aacttagaaa gtaattatag
     6421 caaatattct ataagtaaaa ataacgatag tattcaaaat caaaaaataa ctattaacta
     6481 tttactagct ttaaacaatt ctataatgga tttatcagaa gagttggata agtcaacaaa
     6541 tgaacttgaa aaagctagaa agcagcttat aagcaaacag atagagagaa aatcattaga
     6601 aaaattaaaa gaaaaaaagt atggacagta ttataaagaa gaaaatttaa aagaacaaaa
     6661 cactaatgat gagtttgcaa gtatgagtta tttaaggaat agacaagttc tataagaata
     6721 gtaggaagtg aggatattat tgtatgaaga tacaagcaga ttcttataat attattaaag
     6781 atattgggga tagaaaaagt tcatctaaga acaaaaatat aaaaaataat aaatttgaag
     6841 ataatctata taaggcaaca gaccataaaa aggttaaaga tagaagggaa gtaagcaaaa
     6901 tattagctca gataaaccgg aaaatagtga taatgagtgt catttagatg aagataaaag
     6961 taatcactta gaagatgaaa atacatatga aaaagattgt agtaagaata atgaagcttt
     7021 gcagcaatta ctgaatcttt taaaggataa ttataaaaaa gataaagata taaacactat
     7081 attgaataat atagaaaaac taagtatatc agatgaatta aaacaagaac ttaagcttaa
     7141 taaaaatata ttaaataaga ttgcaaatca aaattcagag ctaaataaag ctaatataaa
     7201 taactctaat gatatagaaa atttagacat agttaaatta agagaacttt tggaagataa
     7261 tgctaataaa gatattgaag taattactaa aactacagaa aatgatacta aaaatataga
     7321 tttgtatagt tttgatagca atagaatgga taatcttaac tcaaataaac agaaagatga
     7381 tagctctgat attttggaaa aactagcagg ggtaaatgga aataagagtg ggaattttgg
     7441 acaagtaata aataaaaatg ttgatatgaa taaaattaaa aatgataatg tcaatttaaa
     7501 acagatagaa tcaaatgtaa tggatgactc tataaaagct attaagcata tgaaaacaaa
     7561 tgatatacaa gaattgacaa ttaaattaag accaaaagaa ttaggagata tgaatataca
     7621 attgttaaaa gatggtgaaa gtatgagagc tgttgtgact gttttcaata aagatgtctt
     7681 tgactctata aataaaaaca tagcagattt aaagcaacat cttgaactta ctaatgtaaa
     7741 tataaaagat gtatcagtgc aaatgcacag cgataataca aatacatctg atacctttga
     7801 taaagcattt gaacaacaga atagacaaaa taaccaagaa aacatgagta agaagaatac
     7861 aaatgataag cataataatg tagtcataga agatgacatt aaagaaaata ttattgatga
     7921 tgatagagta gatttactag cttagtaagg gggaagtatt gcatgtacgg aatagcaacg
     7981 gctttggcag gaactcaggg aaactatagg tcaaataact taagccaact tgaaagaaat
     8041 attaatgata ttgccaataa acaagttaga agcaaaggaa atcagacagt aacagacaat
     8101 gggactccaa ttataggaca aggtgatgat gctgataaag acttgtttat gaagatactt
     8161 gtggcacaga tgggtaatca agacccaatg aatccgcaag acccaacaga atatgtgtca
     8221 caattagcac agtttgcaac tttagaaaag atgtcagcta tgaatgagaa gctagatgta
     8281 cttttagcct taagtaattc cactctaata aactctgctt tgagtatggc aacatcatta
     8341 attggtaaag aagtagaagt atctggggaa gagaaagaag atgaaaacat tgtaggagta
     8401 gtaaagtcca catatataaa agatggggaa gtacacttag aattagaagt agatggaagt
     8461 gacaaaactg taggtgttaa atatgaaaaa ttacttaaaa taggagaggt agatgaaaat
     8521 tcaggagaag aaaatgactc ttcagaacaa gaatctccag aagaagcata atattaaatg
     8581 agaaaagagg taaattcatg ataaaagcaa tgtattcagg tgtaagtgga atgaaagcaa
     8641 atcaaacaaa attagatgta ataggtaaca atgtagccaa tgctggaact acttctttta
     8701 agaaaagttc agctagaata acagattcat tttatcaaac tgtactatat gcaagtgctc
     8761 caacagctgc attaggagga acaaacttag gacaagtagg tgtaggtagt aagatatcaa
     8821 gtataaataa agatatggta caaggaaatg tacaaccaac taatagacca tctgatttaa
     8881 tgatagatgg agatggatat cttccagtag taagacaagg aacagttatg tatacgagag
     8941 atggttcttt taatttagat acaggattta aagcagctga tggtgctttg aagaatatta
     9001 aaggtggaag acttgtaaat ggtgatggat atatgttaca aggtatgatt tatgatgggg
     9061 aatataaagc tgatactgga gaatttgtta aaaaaggtga tgctaaagga aaagagccta
     9121 ttgtaatacc acttcaaagt ataagtccta aggatggaac agttcaaaat gtactagagt
     9181 ataatatatc aaaggatgga acagtagaat ttttattgag tgatggtcaa agaactcaat
     9241 ttgtctatga tatacctgat ggtgctaagg taggagatac acctgctgga atagataaat
     9301 taaaaggtac aatacaaaaa gtgcaaatat atgcattcca aaatccagca ggcctggatg
     9361 ctgctggagg aaacttgttt aaaccatcag caaactcagg agacccacaa atagcaggag
     9421 ctacaggaac aataatacaa ggggcaatag aagcttccaa tgtagatata gcagaagaat
     9481 ttacagaaat gataatagca agtaggtctt tccaagcaaa cagtaaaata atatcgacat
     9541 cagacgagat acttcaagaa ataataaatc ttaagagata gtaggtacat attatgataa
     9601 gagtaacgga tttaaacgga agaaaataca tattaaattc agaccttata gtgaggattg
     9661 attctgtacc agaaagtagg attctcctta caacaggaga aaaaaacctt gtaaaagagt
     9721 cggtagatga gatagtagat aaagtaataa agtataaaag aaaaataaat gtaggttata
     9781 ttaggagcga aaaataatga aaaaaacaga ttcactgaca tttattggac taatagtatc
     9841 tacagtatta gttttagttg gtgccgcaaa aggaagtagt tcagggttaa agaatttttt
     9901 tgatgtttca tcaatattaa tcacagtgct tggttcattt ggagctctaa tgattacatt
     9961 tactatagat gatataaaac ttataaaaaa tgcattacaa tactcattta agacaatgag
    10021 tgtatcaaag ttagatttac tagaacaatt taaaacactt tctaaaaaag ctagaaaaga
    10081 aggtctttta tcaatagaga gtgatgtaat gggaatagaa gatccattta tgaagaaagg
    10141 gttagagctg tgtattgatg gattggaaat caatgagata aggtccatct tagaactaga
    10201 gatagattct gttgaagata caaataacag atactctaaa ctatttaaaa cttggggaac
    10261 ctttgcacct gcttttggga tgttgggaac actaataggt ttaatacaaa tgttagctga
    10321 ccttacatct ccagatttaa tagcatctgg catgggaaag gcattaatta caacgtttta
    10381 tggttcttta cttgccaata tcgctttgaa cccaattgca tataatatag atgagaagac
    10441 tgaaaaagaa atttatgtaa aggaaatgat gttggaaggt ataataagca tacaatctgg
    10501 ggagagcagt atagtagttg aggaacgttt agccacatac ctttcaaaca atgagaagtt
    10561 agaaattatg aaatccaata aaaatacaga aagagcaatg agcaatggcg cgtaaaaaaa
    10621 ataagaaaaa ggatgagata aatccagatg catggctggc tacttatgca gatactataa
    10681 cactgattct tacatttttc gtattattgt atgcaacatc agttgtagat atggaaaaat
    10741 ttaaaaacat agcagatgcg ttaaaaggtc agttttctgg gacaagtata tttagtacgg
    10801 gttcaagtac aagtgagaaa tctccaatag acagtgtttt agtggataaa aatgataaat
    10861 caaatttaga acaggattta aaagataaag ttaataattc taacttacaa aatagtgtaa
    10921 cagtcaaaga tgatagtaga gggattttac tagagttaga tgattcaatt ttatttgact
    10981 ctgggatttc tgagttaaaa gtagatagta aagctactct taataaagta tatgacatga
    11041 taaagatgat gaaaaataag atagttatag aaggccatac tgataatgta cctgtaaaat
    11101 caagtacaca tgaatccaat tgggatttat cttctagtag agcagtaagt gttgtaagat
    11161 actttgtaga agaaaagggc atggacccta gactattttc ggcaacagga tgtggagagt
    11221 atcaaccttt ggtttcaaat gaaacagcaa agggaagggc tgagaataga agagttaata
    11281 tacttataac tattgactag gaggaagagg tttgttcaaa aataaaaaaa ttattataat
    11341 tattttgata ctgattattt tctcagcggg agcaggtttt tttatattag gagaaggtgg
    11401 aaataaacaa gttgacaaga ttgcaggttt gtttattcca acaggaaaag gtaaagatga
    11461 agtaaagacc gaaaatcttg acttagaaga gatggtatta aagctagctg atgaaggtgt
    11521 aagatattta aaagtatcaa taactgtatc ttatgattct tcatataaag atatagaaaa
    11581 aaatacgcct ttaattaggg ataatattat aaattgtttt atggcaaaaa gggcagatga
    11641 ttttactgct gataatttaa agaacataaa agaagaaatt aaaaatacat taaatataca
    11701 actaggtgaa aatgtaattc aaaatatata tttcacaaat atagtagtgc aataaaagga
    11761 tggtaagaca tgatacttta tttactaaaa atattaatat gtatcccaat aattttaata
    11821 ttgatagtct tatctttaaa aattagccaa ggaactttat taaaaaaata taatgataaa
    11881 tatgtaaaaa tactagatat tgtaaatata agtaaaaaca atagcataat aattttaaaa
    11941 ataggtgaag aaggatgcat tatggcatct tcttcttcta gcatgagtaa aataaaagat
    12001 ttgaccaaag aagaaatatt aaaaatagaa aacgacatta aagaaagaaa ttttaaaatt
    12061 caagatttta aaatggaaag aattaaaaag aaatatgatt tcagtagata tattggaaaa
    12121 tttacaaaaa aggaagataa gtaaatggaa ctattatcaa aattaccttt ggctgatgta
    12181 ccatatacaa gttcaatgca attgttttta tttctaactg cattaatgtt tttaccattt
    12241 gtaatgttca tgatgacaag ctttgtcaga atagttataa gtttatcatt tttgaaatca
    12301 gcattaggat cacagcaagc aattccaagt caaattttgg taggacttgc aatagtattg
    12361 acaatattta taatgagacc agtattaaat gagataaacg aaaaggcatt acaaccatat
    12421 atgaaagaag aagttactat ggaagaagct atgaaggaag cagaaggacc tattaaagag
    12481 tttttattaa cgcaaaccag acagacagat ttagatttat ttgtagaaca ggctggttta
    12541 aaagaaaaga aattaactcg tgaaaatata ccactatctg ttgtagttcc agcatttgct
    12601 ataagcgaac taaaaactgc ttttcaaata ggttttttaa tatatatacc atttttgata
    12661 atagaccttg ttgtggcaag tgttttgatg tctatgggta tgtttatgtt gcctccagtt
    12721 atgatatcat taccatttaa gttattatta tttgtaatgg tggatggatg gaacttgata
    12781 gtaaaaacat tgatattggg atttggatag gagaaaaata gtatgagtga atttatgata
    12841 atgagtgttc ttaaaaatgg catgtttaca ggagctatga ttgcagctcc agtactcatt
    12901 gtttctcttg tagttgggct tttaataagt gtgtttcaag ctacaactca aatccaggag
    12961 caaacattga cttttgtacc aaaactaata gctattcttt tagtagtagc tattggtgga
    13021 agctggatgt tacatactct tattagcttt acttctgaga tattcaatat gatatctctt
    13081 ataactaaat aagtaggata catatgattt ttgtatttat tagaatagta gcattctttg
    13141 gaacactaag aatactattt ccagctggta cacctgcttt atttaagtca ctctttgcaa
    13201 tcattatatc aatattgatt tcaagtacta tgcaaattga atatgcaaca aatatagaca
    13261 acattgtatt gtttacctta tatggtgtaa atgagaccat aactgggatt atgcttggat
    13321 atataaccaa cctatgtttt tatagtatca gaatggcggg ttctatgatg gaccaacaga
    13381 tgggattatc aatgattaat atgtttgacc caaattcaat gactcagaca actttaattg
    13441 ataatcttat gaactggaca gcacttatga tattttttag catggatggt catcatgttt
    13501 taattagagg tataaggtat agttttgagt taattccaat aggaaaacca tttgtagata
    13561 ataacataga ttatataata aacatatttg tgcagtgctt tttaactgga ttcaaaatag
    13621 caatacctat tgtactttgt ctgcttatgg cagattttat tttagggctt atatcaagaa
    13681 gtgtacctca attaaatgta atgatagttg gtatgccatt aaaaatattg gttggtattg
    13741 cattatttat catatcaata cctttaattg tcaatcaaat aagtcattta ttaagtcaaa
    13801 taccaaagat gtatgaggga acttttgcac tagctcctat gttttttatg ggttcagcag
    13861 ataaaacaga agaagctact ccaaagaaaa agggagaaca aagaaagaaa ggtaatatag
    13921 caaagagtag agaattaccc gttgcaatga ctctacttgc attcacctta ttagtaccta
    13981 cattattttc atatgtagta gatacactta aatcttcgct taattatttt ttgagtctag
    14041 atttttatat gaacataaat tattcaaacc tagagaaatt agttatagca ggattaatgg
    14101 atttttttaa gatattttta ccaatagcta ttcccttttt agttttaggc ataatagcaa
    14161 acctatttca ggtgggaata ctgtttactg gtgaaacttt aaaaccaaat ttatcaaaat
    14221 taaatccaat tagtggattc aaaaacatgt tttctatgag aagtttgtca accttaataa
    14281 aggatacagc gattatatct attttggctt acataggata tacattcttc caagataatt
    14341 atttagatat attaaagcta ggtaacatat acctaccaac tttaatgtac acagttaaag
    14401 acttagtata ttcaatattg agtaagattt gtgtagctat gatagctata gcagttgcag
    14461 attatgttta tcaaagatac agtcataaaa agcaactgag aatgacaaaa caagaagtta
    14521 aagatgaata taaaaactca gaaggagacc cagaagtaaa agctaagata aaacaaaaac
    14581 aaagacaaat ttcgtctcaa aggacaatgc aagcagtacc aagtgctact gtaatagtaa
    14641 ccaatccaac ccacttatct atagcagtga gatatgaaaa agggaaagac caagctccag
    14701 tagtggtggc aaaaggtgca gattatttag cttttaaaat aagggaaatt gcaaagggaa
    14761 atgacatccc tataatagaa aacaaaccta ttgctaggtt gttatataag caagtagaaa
    14821 tagaccaaga aattccagag gacatgtatc aagcttttgc agagatatta gtggcagtat
    14881 ataaaatcaa aaatagatac aaagtcccca aaaggtagga taagtaatga ataagtttaa
    14941 tttaaaggaa aatatggatg taatagtggc atttggtgtt gtagggattg ttcttatgat
    15001 gatagtgcca ttacctacat ttatattaga tattttactg gcaattaaca taagtttatc
    15061 tgtgctaatt ttactaatga cattatttac aacaaatgta cttgatttat ctatatttcc
    15121 aacagtgtta cttgtgacaa cactatttag attgggatta aatctttcat caactagatt
    15181 gattttaaca cagggatatg caggtgaagt tatagaggca tttggaagtt ttgttgtagg
    15241 tggaaattac gtagtaggaa taattatatt cttaattata ttaattgttc aatttgttgt
    15301 tataaccaat ggttctggaa gagtatctga agtaacagct agatttacgt tagatgccat
    15361 gccaggtaag cagatgagta tagatgcaga tttaaatgca ggagttatag atgacaaaac
    15421 tgctagaaaa agaagaaaag agcttcaaca agaagcagat ttttatggtt ctatggatgg
    15481 agcaaataag tttgtaaagg gagatgccat agcaggtctt atagtaacag caataaacat
    15541 aataggtgga attgtaatag gagctgtaat gctgaatatg actcttatgg gtgcagcaca
    15601 gacatatgta agacttacta taggggatgg tcttgtaagt cagatacctg ctctattaat
    15661 atctacatca gcaggtataa tcgtaacaag agcttctact gatgaaaact ttggtggatt
    15721 agtaggtaaa cagttaacgg caataccaaa agcagtaatg atgactggtt gtgttctaat
    15781 cgtacttggt atgatgcctg gattacctaa accagcattt ttttcactag gtataggagc
    15841 tatagcagca ggttactttt taggaagaga aaagaaagat actttagaag acttggagtt
    15901 tgaaaaacct gatatggtaa acccagataa aaatgaagta gaagatgtaa caaacttaat
    15961 aaatgtagaa tcaatagaag tagaaattgg atatggttta atatctttag ctgatgaatc
    16021 agcaggagga gatttacttc agagaatagc atcaataaga agacaatgtg caatagacat
    16081 gggtatagtc gtacaaccca taagaataag agataactta cagttaaatc caaaccaata
    16141 caatataaaa ataaaaggaa atgtagttgg tgggtatgag ataatgccta atatggtttt
    16201 atgtatggat cctatgaatc aaggatttag catatttgga ataaagacaa ttgaacctac
    16261 ttttggaata gaggcacttt ggatagaaag tgacaaggta gaagatgcag agttaaaggg
    16321 ttatacagtt gtagattcat ccacaatact tataactcac ttactagata taataaaatc
    16381 aaatgcacac gaattactgg gaagacaaga agttaagact attatagatg cagcaagaga
    16441 aaattatagt gctgtagtag atgaattgat accagatttg atgacacttg gtgaaattca
    16501 aaaagtactt aaaaatctgt taagagaaaa agtaaatata aaggatagag ttacaatact
    16561 tgaaacgctt gcagaccagt ctagaaatac aaaagatata gagcttctta ctgaatatgt
    16621 aagaatagcc ttggctagaa gtatttgtaa taatttagtt gatgatgata agacaattgt
    16681 agtggctaca ttgtctccag aaactgaaga gttgatatct aataatttac agaggtctgt
    16741 aaatggaact tatccagcag ttgacccaga aaatacaaat aaaatatttg aaagtataca
    16801 agaagtaatg agcaatgtat atttcaatca taatatacca gtaatagtag tatcaccaaa
    16861 gataagagct ccatttagaa aattagttga aattgtatat cctaatttga ctgtattatc
    16921 attaaatgaa atacctaacg atattaaaat caaagcagaa ggtgtggtga gcatatatga
    16981 tgacgaaaaa gtatacagct aacacaattc aggatgctat gaatctagcc aaaatggaat
    17041 tgggtgacaa tattacatta atagataaaa aagaagtaag aaagtctgga atacaaggta
    17101 tcttttcaaa gaaagatatt gaactaacta ttggatggga aaagagagaa aacgtagaac
    17161 aaaaagattt aaaacgagag atagaacaat taaagtcaat tattaacaat atggggtttg
    17221 ataataagaa tgataatgat atagataaaa tatgtaaaaa tctactaagt ttagaattga
    17281 atgaagaaat tgtagaatct ataagaattg atttgcaaga aatgaagttc aatggaatcg
    17341 atacaagtaa aaatttagta gaaattttaa agaaaaagat taaaatagaa aatcaagtaa
    17401 taaatggtaa aattgctcta gtcggaccac caggagtagg taaaacgact acaatagcaa
    17461 agttagccgc aaaattagtt tttgaagaaa ataaaaaagt aggagtaata actatagata
    17521 catacaggat tggtgctgta gaacagttga agatatatac tgatataatg aatattccct
    17581 ttaaaggggt aataagtcct gatgaaatgg aattggcact tgacgagatg aaagattgtg
    17641 atgttgtatt aatagataca acaggtagag gctacaaaaa ctctatgcaa atactagaaa
    17701 tcaaaaatct tatagataaa gctgaaactg ataatataca tttagttttg aattgtacaa
    17761 caagagaaag tgatacaaaa gcaattatag attcatatag aaatgtgaat tttaaaagct
    17821 taataattac aaagctagat gaaacaataa catatggctc aatatttaac ataatgaatt
    17881 atgcacaaaa accaatatca tatattacaa caggacaaaa tgttcctgat gatattataa
    17941 aacctaatga agataagatt ataaggttac tattaggagt tgaaagtata tgatagacca
    18001 agctcaaatt ttgagaaaaa tagcaatgga aaaaagagga cttgatgagt ttatagtaga
    18061 gaatgagaat gtacctaaga taattacaat agcttctggt aaaggcggtg ttggaaagag
    18121 taatctcgct acaaatttgt ctatatgctt gaccaaactt aataaaaaag ttcttatatt
    18181 agatgcagac ataggaatgt ctaatataga tataataatg ggggtaaatg taaaagggac
    18241 tataattgat gtaattaatg gcgaaaaaaa tatagaagat ataatttcac agactaagta
    18301 tggtgtaaat ataatatctg gaggttctgc ccttaatcat atagaagact ttacagaagc
    18361 tcaaagaaat aagtttatac atagcataga acaaattcac gatgtggatt ttataataat
    18421 tgatacagga gctggtatga gcaaaagcct attgtcattt atatactgta gtactgaatt
    18481 tttcttaata acaactccag aaccgacatc attgactgac gcatatagtt tattaaaagc
    18541 tataagtaat tttggcataa agagaagtgc aaatataata atcaataggg taattgattt
    18601 agaagaagca aaatctacat acaaaagaat aaaaatggtt gtggacaaat ttctaaacct
    18661 taatctagaa ttgtatggat atataataga tgacaaaaaa gtaagtttat gtgtaaaaaa
    18721 acagatacca ttcattttag aatatcctac aagtattgca tcaaaatgta ttatagccat
    18781 agcaaagaga atggtaagtc agtcaagaga agatattgtt gataataaaa gttttctaag
    18841 aaagatgttt agtatattta aaagctaagg aggcgtagtt aatgaataga gaagaattaa
    18901 taaaagagaa tatgcctctt gtaaagagta tagcaagaaa attttttata ccagggaaag
    18961 gttttgaata tcaagactta gtaaatagtg gagtcattgg attgattgat gcaataaata
    19021 aatttgatgc tgaaaaaggg gcaaagtttt ctagttactc ttatataaaa ataaaatctg
    19081 ctatattaga tgaaattaga aatcaaagtc caatttctaa acataatcta actaaagtaa
    19141 ataagtataa tagagtggta gaaaagttgc aatctaaatt attaagagag ccaacttcat
    19201 atgaaattgc aaaagaatta aaggtttcag aaaaagaact tcatgatatc gaaagtaata
    19261 tagatatgtt aaatattgta tcattaaact atgtaatctt tgaagataca aatgaaactg
    19321 tacaagatgt aataagtgat agagaagagg aagctccaga aaatataata gaagaagaag
    19381 aaaagttaga gattctatcc aaagcaatta gtaatttaaa tgaaagagaa aaattaatac
    19441 tttcactgta ctattatgaa gatttaaatc taaaggagat agggaaagtg ctaggtgttt
    19501 cagaatcaag agtttcacaa ctccacagaa aatcaataag aaacttaaga aacaagataa
    19561 aagaacttaa atattctata tagatggtga ttgataagat gatacaaatt atattaatag
    19621 tagtgtctat tttaataata gtaactatag ttataaattt acataaggaa tcaaaaaata
    19681 aagataacag atactttgat aaaatatttg agcaagaata tgaagcaaat gatagattaa
    19741 taattgcaga aaaaagaaga ttctttttag acaaagtact tgcagaaaaa agaattaata
    19801 gtcatataaa agtttatgaa aattataacc taataaaggc taatgaagaa agaaaggaaa
    19861 acatatttat agaatcaaaa aaggaagtaa gacaagaaaa tgagttatct cttaaagtga
    19921 aacatcttat aagttcaggt tatgatgatg tggaaatatg taagatgcta gatattggaa
    19981 agggggaact gttattaata aggagttgtt acaaaatata aggatattat tatgtgataa
    20041 aaaagtattc ttaggaatag gtattggtat attaatatca actttatgta taatgctttt
    20101 tagtaataat gatatgagta aggcagagat agaaaaaaag gccagagcgt taggcatgaa
    20161 atatacaagt gagatgaaag ttttagaata gatgatattg tttagacatt tacaaaaaag
    20221 gaggtcataa tgtgataaga ggattatata cagcagtttc tgctatgata actaatcaac
    20281 aaaagcaaaa tgttgttgtc aataacctag ctaatatgga tacaaatgga tataaaagta
    20341 aacaactttt gactaaaagt tttgatgaat taaagttgga gggttacaat aactacgcaa
    20401 atggaactaa acaaaagcag attataggag atataagtcc aggtatttct atggatgaaa
    20461 ctatcacaaa ttttaatcaa ggacctataa aaactactga taataaaatg gatgtagcta
    20521 ttcaaggcaa gggatttttt ctagttagtg atgcagctgg aaatcaattt tacactagaa
    20581 atgggaactt cagaacagac aatcaaggtg accttataac aagtgaaggg tattatgtac
    20641 ttgggacgaa tactgctact ggtgctgtag gtcatataaa tgtaggaaat caaaaatttg
    20701 aagtggcaaa agataataca atatcactag acggaaatgc tatgtataaa tttaatattg
    20761 tagattttaa taactacaat aacttaaaaa aagaaggaga taacttatat tctggaggag
    20821 gagctatgaa agtaaataat gcacttacaa tacaaagtgc gatagagtcc tctaatgtag
    20881 atatggtatc tgaaattaat aatatgatga caatatcaag agaatatgag gcaaatcaaa
    20941 agataattca ggctatggat tctaaattag caaaaatagc aagtgagatt ggttcagtaa
    21001 gataggtaat aggaggtgaa tttttatgta cacaatgttt tatactagta aaacagcttt
    21061 atcagcaaat caaagtaaac tagatataat atctaacaat atagcaaatt ctgattcaac
    21121 aggatataaa aaaataaata tggaatattc tgatttagtg gatgaagtac taaatagacc
    21181 atcatatcct acaaatggca atgatatatc gactggaaca ggagctaagg caacagctcc
    21241 catgagaaat tatgaacaag gtgcattggc tcctacagat agtaagagta atttggcaat
    21301 agatggagaa ggattcttta gagtgataag aaaagatggt acatatgcat atacaagaaa
    21361 tggtggattt aatgtagatg ctttaggtaa gattgtagat gataatggaa atatattaga
    21421 tgtccaattt gatgcaggat ataactataa taatacaaat atagatagta caaacctgac
    21481 agtttcaaga aatggagagc tattcgtaga taataaaaaa ataggaaaaa tcaacttata
    21541 tcaacctata ggaactcaaa attttatatc tgaaggagat agtttattcg tcgcaactga
    21601 tgcagcacag attaaacaag ttgagaaagt cgatatagtt caaggctata gagagaggtc
    21661 aaatgtttct ttacaagaag aatttgttga cttaatagcc actcaaagag catttcaaat
    21721 gaactcaaag ggaataaaga cagcagatga aatgtggcaa atagcgaata atttaagagc
    21781 taaataatta tgtaaggtga ggaatattca tgaatgatat gaaagagtac gattttggca
    21841 aacctcagag ttattcaaga gaaaatttaa cttgtttaaa ttttttatta gctgaatttt
    21901 gtaaaaaata taaaaactat ataatttatg aacttaagtg taattctagt atggttgttg
    21961 atagtataga ccaagtaaat tatcagactt ttttagatag agtaacttct tcatgcgtag
    22021 tagtacaaaa tgcaatggaa cctgttatga aaaacttttc ttttagaata gatagaagtg
    22081 tagctgatat gtggattgat ataacttctg gaggaactgg agttgtaaag gataatgata
    22141 gagagcttac agaacttgat aaaaaagtgc ttttacacct tatggatgat ttagtaagaa
    22201 atatgcactt atttgagggt tttgaaaata tacaagtatt ggatacacat acacatatta
    22261 atttgccaca attatgttct ccaactgcac cagtatgcgt tgtagattta aaagtgctaa
    22321 atgataatga gtatattgga agtgtttctc tttgttttcc atacaatggt ttagaggctc
    22381 tgttagaaag tatatctgtt atagaatttt ttgataatga tgtaggagat gattcagagg
    22441 aatttaccca aaaaatctat aatagtgtat ctaatataga attatcagtt attgcagaga
    22501 taggaaaagt atcaattaat gttgaggatt tacttaaact agaagttgga gatgtaatag
    22561 taacaaataa aaaaataaat gattatatag atatatttgt agaaaattca aaatcataca
    22621 cagcaacacc aggatttata tcaagtaaaa aaggtgtaaa aataaatgat gctgttggaa
    22681 aagaggtgta gttatggaca atagtaatct tatttcagat gaagaagcaa agatgttatt
    22741 aaatgataaa gttgaaagtg aagttgatgg agatgatgag ttagccttag atgtctctga
    22801 agttaatcga aataatatac aaaggatact tgaccttaag ttagaattat ctgtagttat
    22861 aggaagaact aagatgactc taagagatat tttaaattta cataaaggtt ctcttattga
    22921 actggatact ttagcagacc aagatgtgga aatactaata gataataagg ttttggctta
    22981 tggaaaagta gtggtggtag atttaaattt tggtgtaaag ataacaagta tagtaagtga
    23041 agaagacatg gtaaaatctc ttgtttagag ataacatcaa ttaatactta aggcatgagg
    23101 tggtacttat tttaaactta aatgatataa aaaaagatat actaaaactc aataaaaaag
    23161 actcatgttc tctatataat gaatctatta ataatataaa taataattgt atatcaactg
    23221 gattaaaatt tttaaaacaa gcaagagatt taaacccaga tgatgttgat atattaaatc
    23281 tcacaggtct tgtaaactta ctaaaatgta attttgatga tgctgtagaa agtttctata
    23341 agagttcact ttgtgaaaaa actgctctgt gtgaaaagta tataaacatg cttacatctg
    23401 aggagttttt aattttcttt gaaaagtaca atcaacttat aaggttaata aataaaggaa
    23461 tgtataaaga agctatacaa gggtttaaac tcataactga ccaatactgt gatttaatag
    23521 aaccttatga gttacttgcc ttactgtatg acaaggaaga agaatatata aaatttgatg
    23581 aatgtttaga agtattgaag attattgata aggaaaatta tttattaaat caagaaaata
    23641 acacattaga tatgtataat agtgctaata tacaaactaa aagtaatata aaagtagatg
    23701 attataagaa tgagttttta cataaaagta gtagtaatca taaaattaat gattataata
    23761 atgtaactaa agaaaagagt tcaagcaaaa accagaaaag ttcagattct aataagaaaa
    23821 aaagtattaa aaaaaataag tacctatata tagccataat attaggaata ttattagtag
    23881 gacaaagtat atatagttct tataagatga ataatttaac tgataaaata tctaaaaata
    23941 atgaaactaa aaatgaagag tcaatagatt ctaacttgac taagaaagaa aataatatag
    24001 aagaaaatga agatatgagt aaggcttcta atataaataa gagtaataaa aacattaata
    24061 aagaggatga tgtaaaatct aaaaaaaata ctgtaaaaaa tgaagatgat aaagattctg
    24121 acttatttac agaggatgaa ttgatgtcta aggcgaatac tttaaaatca gaaaagaaaa
    24181 ctaaatcttc tatacaacta tataagaaag ttgcagatat aggtgaaaat aaagggaata
    24241 catctgaagc aacttatcaa gttgctattc tcagtgaaaa gttaaaagac tataaaactg
    24301 ctgaagaata ttataaaatg tatgtagaaa attactcaga aaaagatgct tattttgatg
    24361 aatcttatta taatttaggt atgatgtact ataacaatgg tgatttaaaa aattctaaat
    24421 tgacattaaa gaagttggtt aataaggtac caaatagtat gtataataat tcaaaagtaa
    24481 aagaaatttt aaaagaagaa tagttaaatt agataagaaa aataaattat tttattttaa
    24541 aataatatga ttataatata ttgacatacc attttaaaaa atttaaaata ttaattataa
    24601 aatgaggagg gataaaaaat ggaatttgaa aaagggagta tttcaattca tacagaaaat
    24661 atttttccta taattaaaaa atggttatac tctgataaag acatatttat aagagagctt
    24721 ataagtaatg gatgtgatgc agtaagtaaa cataaaagac ttgtatcact aggagaaata
    24781 tcagaaaata agtcatcaga ttataaaatt acagtatctg taaataaagg agaaggtaca
    24841 cttaaattta ttgacaatgg aattggtatg actgaagaag agataaaaaa atacataaat
    24901 caagttgctt tttcaggtgc tgaagatttc tttaataaat ataaggataa aatggaagag
    24961 tcaaatgata taataggtca ttttggatta ggattttatt ctgcatttat ggtgtctaaa
    25021 aaggtacaaa tagatacact ttcatataca gaaggagcga ctcctgtaag atggatatct
    25081 gaaggtggta cagaatacga aatatctgaa tcagatgcta gaaatgatag aggaactact
    25141 ataacactat ttattgatga tgatagtaaa gaatttttag atgaatttac tgtaagagga
    25201 ataataaata aatactgttc tttcttacca gtagaaatat atttagaaga tgttgaaaga
    25261 ttagaaagag aagctaaaga agcagaagaa aaagctaaaa aacaaaagga agatggaaaa
    25321 gaagagattg tagatgcaaa agtaattgag cctttaaacg acactaatcc tctatggtta
    25381 aaatctccaa aagactgtac tgatgaggag tataaagagt tttatagaaa ggtattcaat
    25441 gtatttgatg aacctttatt ttggatacat ttaaatgtag attatccttt caatttaaag
    25501 ggtatacttt acttccctaa attaaaaaat gagtttgaac tgactgaagg aaaagtaaaa
    25561 ttatacaaca atcaagtgtt tgtggctgac aatataaaag aagttatacc agaattttta
    25621 cttttattaa aaggagttat agactgccca gacttaccat taaatgtatc aagaagtttc
    25681 ttacaaaatg acagggatgt aagcaaaatt tctaaacata taattaaaaa agtagctgat
    25741 aagttaaaat ctctttgtaa aaatgaaaga gaagaataca ataagttttg ggatgatata
    25801 caaatattta ttaaatatgg ttgcttaaaa gatgaaagtt tctatgagaa ggtaaaagaa
    25861 tgtatattat tcaaaactat tgatgatgag tatataacat tacaagatta tttagaaaaa
    25921 tgtaaggaca aacatgaaaa taaggtattt tatataagtg ataaagaaca gcaatctcaa
    25981 tacattaaac tatttaaaga atacgactta agtgctgttg tcttaaactc atcaatagat
    26041 actcatttta tttcatttat ggaatataaa gagaatggag ttaagtttaa tagaatagat
    26101 gcagaccttt ctgatgtatt aaaagataaa aatgaaaata aagatagtga agaaaacaaa
    26161 gaagagatag ctaagataga aggtctgttt aaagaagttg ttggagaaag agtgaagaat
    26221 tattctgtag aaggattgaa aaatgaagac actccagcta tggtgttagt atcagaacaa
    26281 tctattagaa tggcagaaat gcagtcaaga tttgctggaa tggatttagg aatgaatttt
    26341 gaagaagaaa aaactcttgt aataaatgag aacagtccaa taatcaaaaa attggtttct
    26401 cttaaagatg atgaggaaaa gaaagataag attacgctta tttgtaacca gatagcagat
    26461 ttagctttac tttctaataa agaattaaag ccagatgagt tagattcatt tgtacaaaga
    26521 agtaataagc ttatgagtct tttgatagaa ttataagatt gaatttgaat acattgaagc
    26581 aaatttataa aaagtattca atatcagtga taagaaagaa gtgtctcaaa atgaactttt
    26641 cagttcatga ggcgcttttt ttatgtgaaa ttaaatttat tttaatcatt tcaacaatga
    26701 aaaatatatt tatctctatt ttgagacaga ccgttcttta tttttttatc tttggttaat
    26761 ttttaaatat ttaagtaggt tctaataaaa aactctattt agttaaatat agttaacttg
    26821 atatataata agataataca tataattaag taaaagattg ttttttagtt tatgtttaaa
    26881 tacataatta cactttgtta aaaacataaa attattacta aagtagaaat aggaggtttt
    26941 agcatgaatt ttaattataa tttgccagta aatatcttat ttgggagagg cagaattaat
    27001 gatgtgggaa aagaagtatc taaatatggc aaaaaagtat tgatagtaac aggtaaaaat
    27061 agtacaaaga aaactggatt acttgataaa acaatagatt tactaaaaga ctctaaaata
    27121 gaatatgaag tttttgatag agtagaacaa aatcctctta taactactat atattcagga
    27181 gtagaaatta taaaatcaac tggatgtgat tgtgttttag ggcttggtgg tggaagcatt
    27241 atggatgctg ccaagagtat agctttttct tataaaaacc caggagattt aaatgattat
    27301 atatttggaa ttaggcaagg tgaagaagct ttacctataa tcttagttcc aacaacatca
    27361 ggtacaggta gtgaaggaaa ttgttttgca gtacttacaa attcagaaac taaagataaa
    27421 aaatctataa agaagaatag tatgtatgca aaagcatcaa taattgaccc agaacttatg
    27481 gttacaatgc caaaacatat aattgcatca gttggatttg atgcacttgc ccataatatg
    27541 gaagcatatc tttctaatgg aagaaaccct cttgcagatg tacaagctat ttatgggatt
    27601 gaacttatat cagaaaacct aataaaggta tataatgatg ttaatgattt agaagcatgg
    27661 gaaaaaataa cacttgcaag tactattgga ggaatgacga ttggtacagc gggtacagcc
    27721 ttgccacatg gaatggagca tcctgtaagt ggtcttagag atgtaatgca tggaaaagga
    27781 cttgcagctt tgactcctac tattatagaa agttcatggg atagtgatat tgaaagattt
    27841 ggtaatattt caaaggtatt aggaggaact tgtgcagaag attgttcaga tgcaattaga
    27901 aatttcctta aaaaaataga tttagatata aaactaagtg atttaggtat tgaaaaatca
    27961 gatatagatt ggttaactga taattgtatg aaaatatcag ttgcaaatat taagagacat
    28021 ccaaagtatt ttaataagga acaaataaag gaaatgtacc ataagtcttt ataatttgac
    28081 tttacatatt tagttttata
//
LOCUS       DAEPUT010000048        28009 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.050, whole genome shotgun sequence.
ACCESSION   DAEPUT010000048 DAEPUT010000000
VERSION     DAEPUT010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28009
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.050"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            190..744
                     /gene="tcdR"
                     /locus_tag="KRL22_002294"
     CDS             190..744
                     /gene="tcdR"
                     /locus_tag="KRL22_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HBH1272781.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            1062..8162
                     /gene="tcdB"
                     /locus_tag="KRL22_002295"
                     /gene_synonym="toxB"
     CDS             1062..8162
                     /gene="tcdB"
                     /locus_tag="KRL22_002295"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HBH1272782.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGIASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDDKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8284..8784
                     /gene="tcdE"
                     /locus_tag="KRL22_002296"
     CDS             8284..8784
                     /gene="tcdE"
                     /locus_tag="KRL22_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HBH1272783.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            8863..9024
                     /locus_tag="KRL22_002297"
     CDS             8863..9024
                     /locus_tag="KRL22_002297"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272784.1"
                     /translation="MKLIMKTREQMPRDTQVLNTYNFEASVHYYIDDKVVYQTLVHKD
                     GAWSVGKIY"
     gene            9113..9295
                     /locus_tag="KRL22_002298"
     CDS             9113..9295
                     /locus_tag="KRL22_002298"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272785.1"
                     /translation="MRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9512..17644
                     /gene="tcdA"
                     /locus_tag="KRL22_002299"
                     /gene_synonym="toxA"
     CDS             9512..17644
                     /gene="tcdA"
                     /locus_tag="KRL22_002299"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HBH1272786.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNRLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNNSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTDANNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(17979..18677)
                     /gene="tcdC"
                     /locus_tag="KRL22_002300"
     CDS             complement(17979..18677)
                     /gene="tcdC"
                     /locus_tag="KRL22_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HBH1272787.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            19103..19348
                     /locus_tag="KRL22_002301"
     CDS             19103..19348
                     /locus_tag="KRL22_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HBH1272788.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(19566..19835)
                     /locus_tag="KRL22_002302"
     CDS             complement(19566..19835)
                     /locus_tag="KRL22_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH1272789.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(20633..21370)
                     /locus_tag="KRL22_002303"
     CDS             complement(20633..21370)
                     /locus_tag="KRL22_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272790.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            complement(21382..22143)
                     /locus_tag="KRL22_002304"
     CDS             complement(21382..22143)
                     /locus_tag="KRL22_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272791.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            complement(22143..23057)
                     /locus_tag="KRL22_002305"
     CDS             complement(22143..23057)
                     /locus_tag="KRL22_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272792.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            23228..23935
                     /locus_tag="KRL22_002306"
     CDS             23228..23935
                     /locus_tag="KRL22_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1272793.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            23980..25386
                     /locus_tag="KRL22_002307"
     CDS             23980..25386
                     /locus_tag="KRL22_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1272794.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRNGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQTLNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSKNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            27145..27534
                     /locus_tag="KRL22_002308"
     CDS             27145..27534
                     /locus_tag="KRL22_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1272795.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT        11076 a         3111 c         4287 g         9535 t
ORIGIN      
        1 ttgctaaaat actttattta ttagaaaaag attactaatt aattattaaa attaatgtat
       61 tcataatgca tattttcata taaaatttaa tttatttgcc gattatataa ttataatgac
      121 tgatttaatt ccaatgttgt caaaattttc aaataaatca tcattataaa tataagagag
      181 gatgatttta tgcaaaagtc tttttatgaa ttaattgttt tagcaagaaa taactcagta
      241 gatgatttgc aagaaatttt atttatgttt aagccattag taaaaaaact tagtagagtt
      301 ttacattatg aagagggaga aacagattta ataatatttt ttattgaatt aataaaaaat
      361 attaaattaa gtagcttttc agaaaaaagc gatgctatta tagtcaaata tattcataaa
      421 tcattactga ataagacttt tgagttgtct agaagatatt ctaaaatgaa gtttaatttt
      481 gtagaatttg atgaaaatat cttaaatatg aaaaataatt atcaaagtaa gtctgttttt
      541 gaggaagata tttgtttttt cgaatatatt ttgaaagaat tatctggtat tcaaagaaaa
      601 gttatttttt ataaatattt aaaaggatat tctgatagag aaatatcagt gaaattaaaa
      661 atatctagac aagctgttaa taaggctaaa aatagagcat ttaaaaaaat aaaaaaagac
      721 tatgaaaatt attttaactt gtaattaatg agcttaaaga aatatttaca atagaaatca
      781 aattttagaa ttaactttat tgtaaaatca ataacttaat ctaagaatat cttaattttt
      841 atattttata tagaacaaag tttacatatt tatttcagac aacgtcttta ttcaatcgaa
      901 gagcaaatta atcaactgag tgtcttaaat ttaaaatgtt aggaagtgaa tgtatatgaa
      961 aacctaagta gatattagta tattttataa atagaaagga ggatatataa aagagtttta
     1021 gcatttagat gtaaaaatat tatagtaaag gagaaaattt tatgagttta gttaatagaa
     1081 aacagttaga aaaaatggca aatgtaagat ttcgtactca agaagatgaa tatgttgcaa
     1141 tattggatgc tttagaagaa tatcataata tgtcagagaa tactgtagtc gaaaaatatt
     1201 taaaattaaa agatataaat agtttaacag atatttatat agatacatat aaaaaatctg
     1261 gtagaaataa agccttaaaa aaatttaagg aatatctagt tacagaagta ttagagctaa
     1321 agaataataa tttaactcca gttgagaaaa atttacattt tgtttggatt ggaggtcaaa
     1381 taaatgacac tgctattaat tatataaatc aatggaaaga tgtaaatagt gattataatg
     1441 ttaatgtttt ttatgatagt aatgcatttt tgataaacac attgaaaaaa actgtagtag
     1501 aatcagcaat aaatgataca cttgaatcat ttagagaaaa cttaaatgac cctagatttg
     1561 actataataa attcttcaga aaacgtatgg aaataattta tgataaacag aaaaatttca
     1621 taaactacta taaagctcaa agagaagaaa atcctgaact tataattgat gatattgtaa
     1681 agacatatct ttcaaatgag tattcaaagg agatagatga acttaatacc tatattgaag
     1741 aatccttaaa taaaattaca cagaatagtg gaaatgatgt tagaaacttt gaagaattta
     1801 aaaatggaga gtcattcaac ttatatgaac aagagttggt agaaaggtgg aatttagctg
     1861 ctgcttctga catattaaga atatctgcat taaaagaaat tggtggtatg tatttagatg
     1921 ttgatatgtt accaggaata caaccagact tatttgagtc tatagagaaa cctagttcag
     1981 taacagtgga tttttgggaa atgacaaagt tagaagctat aatgaaatac aaagaatata
     2041 taccagaata tacctcagaa cattttgaca tgttagacga agaagttcaa agtagttttg
     2101 aatctgttct agcttctaag tcagataaat cagaaatatt ctcatcactt ggtgatatgg
     2161 aggcatcacc actagaagtt aaaattgcat ttaatagtaa gggtattata aatcaagggc
     2221 taatttctgt gaaagactca tattgtagca atttaatagt aaaacaaatc gagaatagat
     2281 ataaaatatt gaataatagt ttaaatccag ctattagcga ggataatgat tttaatacta
     2341 caacgaatac ctttattgat agtataatgg ctgaagctaa tgcagataat ggtagattta
     2401 tgatggaact aggaaagtat ttaagagttg gtttcttccc agatgttaaa actactatta
     2461 acttaagtgg ccctgaagca tatgcggcag cttatcaaga tttattaatg tttaaagaag
     2521 gcagtatgaa tatccatttg atagaagctg atttaagaaa ctttgaaatc tctaaaacta
     2581 atatttctca atcaactgaa caagaaatgg ctagcttatg gtcatttgac gatgcaagag
     2641 ctaaagctca atttgaagaa tataaaagga attattttga aggttctctt ggtgaagatg
     2701 ataatcttga tttttctcaa aatatagtag ttgacaagga gtatctttta gaaaaaatat
     2761 cttcattagc aagaagttca gagagaggat atatacacta tattgttcag ttacaaggag
     2821 ataaaattag ttatgaagca gcatgtaact tatttgcaaa gactccttat gatagtgtac
     2881 tgtttcagaa aaatatagaa gattcagaaa ttgcatatta ttataatcct ggagatggtg
     2941 aaatacaaga aatagacaag tataaaattc caagtataat ttctgataga cctaagatta
     3001 aattaacatt tattggtcat ggtaaagatg aatttaatac tgatatattt gcaggttttg
     3061 atgtagattc attatccaca gaaatagaag cagcaataga tttagctaaa gaggatattt
     3121 ctcctaagtc aatagaaata aatttattag gatgtaatat gtttagctac tctatcaacg
     3181 tagaggagac ttatcctgga aaattattac ttaaagttaa agataaaata tcagaattaa
     3241 tgccatctat aagtcaagac tctattatag taagtgcaaa tcaatatgaa gttagaataa
     3301 atagtgaagg aagaagagaa ttattggatc attctggtga atggataaat aaagaagaaa
     3361 gtattataaa ggatatttca tcaaaagaat atatatcatt taatcctaaa gaaaataaaa
     3421 ttacagtaaa atctaaaaat ttacctgagc tatctacatt attacaagaa attagaaata
     3481 attctaattc aagtgatatt gaactagaag aaaaagtaat gttaacagaa tgtgagataa
     3541 atgttatttc aaatatagat acgcaaattg ttgaggaaag gattgaagaa gctaagaatt
     3601 taacttctga ctctattaat tatataaaag atgaatttaa actaatagaa tctatttctg
     3661 atgcactatg tgacttaaaa caacagaatg aattagaaga ttctcatttt atatcttttg
     3721 aggacatatc agagactgat gagggattta gtataagatt tattaataaa gaaactggag
     3781 aatctatatt tgtagaaact gaaaaaacaa tattctctga atatgctaat catataactg
     3841 aagagatttc taagataaaa ggtactatat ttgatactgt aaatggtaag ttagtaaaaa
     3901 aagtaaattt agatactaca cacgaagtaa atactttaaa tgctgcattt tttatacaat
     3961 cattaataga atataatagt tctaaagaat ctcttagtaa tttaagtgta gcaatgaaag
     4021 tccaagttta cgctcaatta tttagtactg gtttaaatac tattacagat gcagccaaag
     4081 ttgttgaatt agtatcaact gcattagatg aaactataga cttacttcct acattatctg
     4141 aaggattacc tataattgca actattatag atggtgtaag tttaggtgca gcaatcaaag
     4201 agctaagtga aacgagtgac ccattattaa gacaagaaat agaagctaag ataggtataa
     4261 tggcagtaaa tttaacaaca gctacaactg caatcattac ttcatctttg gggatagcta
     4321 gtggatttag tatactttta gttcctttag caggaatttc agcaggtata ccaagcttag
     4381 taaacaatga acttgtactt cgagataagg caacaaaggt tgtagattat tttaaacatg
     4441 tttcattagt tgaaactgaa ggagtattta ctttattaga tgataaaata atgatgccac
     4501 aagatgattt agtgatatca gaaatagatt ttaataataa ttcaatagtt ttaggtaaat
     4561 gtgaaatctg gagaatggaa ggtggttcag gtcatactgt aactgatgat atagatcact
     4621 tcttttcagc accatcaata acatatagag agccacactt atctatatat gacgtattgg
     4681 aagtacaaaa agaagaactt gatttgtcaa aagatttaat ggtattacct aatgctccaa
     4741 atagagtatt tgcttgggaa acaggatgga caccaggttt aagaagctta gaaaatgatg
     4801 gcacaaaact gttagaccgt ataagagata actatgaagg tgagttttat tggagatatt
     4861 ttgcttttat agctgatgct ttaataacaa cattaaaacc aagatatgaa gatactaata
     4921 taagaataaa tttagatagt aatactagaa gttttatagt tccaataata actacagaat
     4981 atataagaga aaaattatca tattctttct atggttcagg aggaacttat gcattgtctc
     5041 tttctcaata taatatgggt ataaatatag aattaagtga aagtgatgtt tggattatag
     5101 atgttgataa tgttgtgaga gatgtaacta tagaatctga taaaattaaa aaaggtgatt
     5161 taatagaagg tattttatct acactaagta ttgaagagaa taaaattatc ttaaatagcc
     5221 atgagattaa tttttctggt gaggtaaatg gaagtaatgg atttgtttct ttaacatttt
     5281 caattttaga aggaataaat gcaattatag aagttgattt attatctaaa tcatataaat
     5341 tacttatttc tggcgaatta aaaatattga tgttaaattc aaatcatatt caacagaaaa
     5401 tagattatat aggattcaat agcgaattac agaaaaatat accatatagc tttgtagata
     5461 gtgaaggaaa agagaatggt tttattaatg gttcaacaaa agaaggttta tttgtatctg
     5521 aattacctga tgtagttctt ataagtaagg tttatatgga tgatagtaag ccttcatttg
     5581 gatattatag taataatttg aaagatgtca aagttataac taaagataat gttaatatat
     5641 taacaggtta ttatcttaag gatgatataa aaatctctct ttctttgact ctacaagatg
     5701 aaaaaactat aaagttaaat agtgtgcatt tagatgaaag tggagtagct gagattttga
     5761 agttcatgaa tagaaaaggt aatacaaata cttcagattc tttaatgagc tttttagaaa
     5821 gtatgaatat aaaaagtatt ttcgttaatt tcttacaatc taatattaag tttatattag
     5881 atgctaattt tataataagt ggtactactt ctattggcca atttgagttt atttgtgatg
     5941 aaaatgataa tatacaacca tatttcatta agtttaatac actagaaact aattatactt
     6001 tatatgtagg aaatagacaa aatatgatag tggaaccaaa ttatgattta gatgattctg
     6061 gagatatatc ttcaactgtt atcaatttct ctcaaaagta tctttatgga atagacagtt
     6121 gtgttaataa agttgtaatt tcaccaaata tttatacaga tgaaataaat ataacgcctg
     6181 tatatgaaac aaataatact tatccagaag ttattgtatt agatgcaaat tatataaatg
     6241 aaaaaataaa tgttaatatc aatgatctat ctatacgata tgtatggagt aatgatggta
     6301 atgattttat tcttatgtca actagtgaag aaaataaggt gtcacaagtt aaaataagat
     6361 tcgttaatgt ttttaaagat aagactttgg caaataagct atcttttaac tttagtgata
     6421 aacaagatgt acctgtaagt gaaataatct tatcatttac accttcatat tatgaggatg
     6481 gattgattgg ctatgatttg ggtctagttt ctttatataa tgagaaattt tatattaata
     6541 actttggaat gatggtatct ggattaatat atattaatga ttcattatat tattttaaac
     6601 caccagtaaa taatttgata actggatttg tgactgtagg cgatgataaa tactacttta
     6661 atccaattaa tggtggagct gcttcaattg gagagacaat aattgatgac aaaaattatt
     6721 atttcaacca aagtggagtg ttacaaacag gtgtatttag tacagaagat ggatttaaat
     6781 attttgcccc agctaataca cttgatgaaa acctagaagg agaagcaatt gattttactg
     6841 gaaaattaat tattgacgaa aatatttatt attttgatga taattataga ggagctgtag
     6901 aatggaaaga attagatggt gaaatgcact attttagccc agaaacaggt aaagctttta
     6961 aaggtctaaa tcaaataggt gatgataaat actatttcaa ttctgatgga gttatgcaaa
     7021 aaggatttgt tagtataaat gataataaac actattttga tgattctggt gttatgaaag
     7081 taggttacac tgaaatagat ggcaagcatt tctactttgc tgaaaacgga gaaatgcaaa
     7141 taggagtatt taatacagaa gatggattta aatattttgc tcatcataat gaagatttag
     7201 gaaatgaaga aggtgaagaa atctcatatt ctggtatatt aaatttcaat aataaaattt
     7261 actattttga tgattcattt acagctgtag ttggatggaa agatttagag gatggttcaa
     7321 agtattattt tgatgaagat acagcagaag catatatagg tttgtcatta ataaatgatg
     7381 gtcaatatta ttttaatgat gatggaatta tgcaagttgg atttgtcact ataaatgata
     7441 aagtcttcta cttctctgac tctggaatta tagaatctgg agtacaaaac atagatgaca
     7501 attatttcta tatagatgat aatggtatag ttcaaattgg tgtatttgat acttcagatg
     7561 gatataaata ttttgcacct gctaatactg taaatgataa tatttacgga caagcagttg
     7621 aatatagtgg tttagttaga gttggggaag atgtatatta ttttggagaa acatatacaa
     7681 ttgagactgg atggatatat gatatggaaa atgaaagtga taaatattat ttcaatccag
     7741 aaactaaaaa agcatgcaaa ggtattaatt taattgatga tataaaatat tattttgatg
     7801 agaagggcat aatgagaacg ggtcttatat catttgaaaa taataattat tactttaatg
     7861 agaatggtga aatgcaattt ggttatataa atatagaaga taagatgttc tattttggtg
     7921 aagatggtgt catgcagatt ggagtattta atacaccaga tggatttaaa tactttgcac
     7981 atcaaaatac tttggatgag aattttgagg gagaatcaat aaactatact ggttggttag
     8041 atttagatga aaagagatat tattttacag atgaatatat tgcagcaact ggttcagtta
     8101 ttattgatgg tgaggagtat tattttgatc ctgatacagc tcaattagtg attagtgaat
     8161 agataaaaat atgttaaata tatcctctta tacttaaata tataaaaata aacaaaatga
     8221 tacactacat aaagtgttct atctaatatg aagatttacc aataaaaagg tggactatga
     8281 tgaatgcaca gtagttcacc tttttatatt tctaatggta acaaaatatt tttttatata
     8341 aacctaggag gcgttatgaa tatgacaata tcttttttat cagagcatat atttataaag
     8401 ttagtaattt taactatatc atttgataca ttattaggat gtttaagtgc aataaaaagt
     8461 cgtaaattta attctagttt tggaatagat ggaggaatca gaaaagtagc aatgatagca
     8521 tgtatatttt ttttatcagt agttgacatt cttacaaagt ttaacttttt atttatgtta
     8581 ccacaagatt gtatcaattt tttaagacta aaacatcttg gaatatctga atttttctct
     8641 attttattta ttttatatga aagtgtaagt atattaaaaa atatgtgctt atgtggatta
     8701 ccagtaccta agagattaaa ggaaaaaata gcaattttac tagatgcaat gacagatgaa
     8761 atgaatgcta aggatgaaaa gtaagtaatg gtagatataa taaagatatt aacaaataaa
     8821 aagtgttatc caaataagaa tagctgaaag ttatcataat tcatgaaact aataatgaaa
     8881 acgagggagc agatgccaag agacacacaa gtattaaata catataattt cgaagcaagt
     8941 gttcattact atatagatga caaggtagta tatcaaacat tggttcacaa agatggtgca
     9001 tggtcagttg gtaaaatcta ttaagctaca ttagttacag atatcacaaa ctataatagt
     9061 taaacataga aatatgtgta aattgtgatg gaaattattc aaaaacacaa aaatacgtga
     9121 tgaaggacaa aatgatatag aaaataagta tcaaacctta ataaatgatt taattgatag
     9181 tttaaaagtt ataggaaaaa tatataaaga aataaaaaca ttaaaaaaat ataagatatg
     9241 tttacaaatt actatcagac aatctcctta tctaatagaa gagtcaatta actaattgag
     9301 tatctttaaa ttgaaatgtt aggaagtgat ttaaatatga aaacttaaat tataaaaaat
     9361 caatattaat ttatttttaa aaaatagaaa ggagtgtata agatttattt tcaaagttta
     9421 aaaacaagaa aatcaattta aatttcagaa ggaataaatg tggttataga agtggattta
     9481 ttatcaaaaa taataatact aggaggtttt tatgtcttta atatctaaag aagagttaat
     9541 aaaactcgca tatagcatta gaccaagaga aaatgagtat aaaactatac taactaattt
     9601 agacgaatat aataagttaa ctacaaacaa taatgaaaat aaatatttac aattaaaaaa
     9661 actaaatgaa tcaattgatg tttttatgaa taaatataaa acttcaagca gaaatagagc
     9721 actctctaat ctaaaaaaag atatattaaa agaagtaatt cttattaaaa attccaatac
     9781 aagccctgta gaaaaaaatt tacattttgt atggataggt ggagaagtca gtgatattgc
     9841 tcttgaatac ataaaacaat gggctgatat taatgcagaa tataatatta aactgtggta
     9901 tgatagtgaa gcattcttag taaatacact aaaaaaggct atagttgaat cttctaccac
     9961 tgaagcatta cagctactag aggaagagat tcaaaatcct caatttgata atatgaaatt
    10021 ttacaaaaaa aggatggaat ttatatatga tagacaaaaa aggtttataa attattataa
    10081 atctcaaatc aataaaccta cagtacctac aatagatgat attataaagt ctcatctagt
    10141 atctgaatat aatagagatg aaactgtatt agaatcatat agaacaaatt ctttgagaaa
    10201 aataaatagt aatcatggga tagatatcag ggctaatagt ttgtttacag aacaagagtt
    10261 attaaatatt tatagtcagg agttgttaaa tcgtggaaat ttagctgcag catctgacat
    10321 agtaagatta ttagccctaa aaaattttgg cggagtatat ttagatgttg atatgcttcc
    10381 aggtattcac tctgatttat ttaaaacaat atctagacct agctctattg gactagaccg
    10441 ttgggaaatg ataaaattag aggctattat gaagtataaa aaatatataa ataattatac
    10501 atcagaaaac tttgataaac ttgatcaaca attaaaagat aattttaaac tcattataga
    10561 aagtaaaagt gaaaaatctg agatattttc taaattagaa aatttaaatg tatctgatct
    10621 tgaaattaaa atagctttcg ctttaggcag tgttataaat caagccttga tatcaaaaca
    10681 aggttcatat cttactaacc tagtaataga acaagtaaaa aatagatatc aatttttaaa
    10741 ccaacacctt aacccagcca tagagtctga taataacttc acagatacta ctaaaatttt
    10801 tcatgattca ttatttaatt cagctaccgc agaaaactct atgtttttaa caaaaatagc
    10861 accatactta caagtaggtt ttatgccaga agctcgctcc acaataagtt taagtggtcc
    10921 aggagcttat gcgtcagctt actatgattt cataaattta caagaaaata ctatagaaaa
    10981 aactttaaaa gcatcagatt taatagaatt taaattccca gaaaataatc tatctcaatt
    11041 gacagaacaa gaaataaata gtctatggag ctttgatcaa gcaagtgcaa aatatcaatt
    11101 tgagaaatat gtaagagatt atactggtgg atctctttct gaagacaatg gggtagactt
    11161 taataaaaat actgccctcg acaaaaacta tttattaaat aataaaattc catcaaacaa
    11221 tgtagaagaa gctggaagta aaaattatgt tcattatatc atacagttac aaggagatga
    11281 tataagttat gaagcaacat gcaatttatt ttctaaaaat cctaaaaata gtattattat
    11341 acaacgaaat atgaatgaaa gtgcaaaaag ctacttttta agtgatgatg gagaatctat
    11401 tttagaatta aataaatata ggatacctga aagattaaaa aataaggaaa aagtaaaagt
    11461 aacctttatt ggacatggta aagatgaatt caacacaagc gaatttgcta gattaagtgt
    11521 agattcactt tccaatgaga taagttcatt tttagatacc ataaaattag atatatcacc
    11581 taaaaatgta gaagtaaact tacttggatg taatatgttt agttatgatt ttaatgttga
    11641 agaaacttat cctgggaagt tgctattaag tattatggac aaaattactt ccactttacc
    11701 tgatgtaaat aaaaattcta ttactatagg agcaaatcaa tatgaagtaa gaattaatag
    11761 tgagggaaga aaagaacttc tggctcactc aggtaaatgg ataaataaag aagaagctat
    11821 tatgagcgat ttatctagta aagaatacat tttttttgat tctatagata ataggctaaa
    11881 agcaaagtcc aagaatattc caggattagc atcaatatca gaagatataa aaacattatt
    11941 acttgatgca agtgttagtc ctgatacaaa atttatttta aataatctta agcttaatat
    12001 tgaatcttct attggtgatt acatttatta tgaaaaatta gagcctgtta aaaatataat
    12061 tcacaattct atagatgatt taatagatga gttcaatcta cttgaaaatg tatctgatga
    12121 attatatgaa ttaaaaaaat taaataatct agatgagaag tatttaatat cttttgaaga
    12181 tatctcaaaa aataattcaa cttactctgt aagatttatt aacaaaagta atggtgagtc
    12241 agtttatgta gaaacagaaa aagaaatttt ttcaaaatat agcgaacata ttacaaaaga
    12301 aataagtact ataaagaata gtataattac agatgttaat ggtaatttat tggataatat
    12361 acagttagat catacttctc aagttaatac attaaacgca gcattcttta ttcaatcatt
    12421 aatagattat agtagcaata aagatgtact gaatgattta agtacctcag ttaaggttca
    12481 actttatgct caactattta gtacaggttt aaatactata tatgactcta tccaattagt
    12541 aaatttaata tcaaatgcag taaatgatac tataaatgta ctacctacaa taacagaggg
    12601 gatacctatt gtatctacta tattagacgg aataaactta ggtgcagcaa ttaaggaatt
    12661 actagacgaa catgacccat tactaaaaaa agaattagaa gctaaggtgg gtgttttagc
    12721 aataaatatg tcattatcta tagctgcaac tgtagcttca attgttggaa taggtgctga
    12781 agttactatt ttcttattac ctatagctgg tatatctgca ggaatacctt cattagttaa
    12841 taatgaatta atattgcatg ataaggcaac ttcagtggta aactatttta atcatttgtc
    12901 tgaatctaaa aaatatggcc ctcttaaaac agaagatgat aaaattttag ttcctattga
    12961 tgatttagta atatcagaaa tagattttaa taataattcg ataaaactag gaacatgtaa
    13021 tatattagca atggaggggg gatcaggaca cacagtgact ggtaatatag atcacttttt
    13081 ctcatctcca tctataagtt ctcatattcc ttcattatca atttattctg caataggtat
    13141 agaaacagaa aatctagatt tttcaaaaaa aataatgatg ttacctaatg ctccttcaag
    13201 agtgttttgg tgggaaactg gagcagttcc aggtttaaga tcattggaaa atgacggaac
    13261 tagattactt gattcaataa gagatttata cccaggtaaa ttttactgga gattctatgc
    13321 ttttttcgat tatgcaataa ctacattaaa accagtttat gaagacacta atattaaaat
    13381 taaactagat aaagatacta gaaacttcat aatgccaact ataactacta acgaaattag
    13441 aaacaaatta tcttattcat ttgatggagc aggaggaact tactctttat tattatcttc
    13501 atatccaata tcaacgaata taaatttatc taaagatgat ttatggatat ttaatattga
    13561 taatgaagta agagaaatat ctatagaaaa tggtactatt aaaaaaggaa agttaataaa
    13621 agatgtttta agtaaaattg atataaataa aaataaactt attataggca atcaaacaat
    13681 agatttttca ggcgatatag ataataaaga tagatatata ttcttgactt gtgagttaga
    13741 tgataaaatt agtttaataa tagaaataaa tcttgttgca aaatcttata gtttgttatt
    13801 gtctggggat aaaaattatt tgatatccaa tttatctaat actattgaga aaatcaatac
    13861 tttaggccta gatagtaaaa atatagcgta caattacact gatgaatcta ataataaata
    13921 ttttggagct atatctaaaa caagtcaaaa aagcataata cattataaaa aagacagtaa
    13981 aaatatatta gaattttata atgacagtac attagaattt aacagtaaag attttattgc
    14041 tgaagatata aatgtattta tgaaagatga tattaatact ataacaggaa aatactatgt
    14101 tgataataat actgataaaa gtatagattt ctctatttct ttagttagta aaaatcaagt
    14161 aaaagtaaat ggattatatt taaatgaatc cgtatactca tcttaccttg attttgtgaa
    14221 aaattcagat ggacaccata atacttctaa ttttatgaat ttatttttgg acaatataag
    14281 tttctggaaa ttgtttgggt ttgaaaatat aaattttgta atcgataaat actttaccct
    14341 tgttggtaaa actaatcttg gatatgtaga atttatttgt gacaataata aaaatataga
    14401 tatatatttt ggtgaatgga aaacatcgtc atctaaaagc actatattta gcggaaatgg
    14461 tagaaatgtt gtagtagagc ctatatataa tcctgatacg ggtgaagata tatctacttc
    14521 actagatttt tcctatgaac ctctctatgg aatagataga tatataaata aagtattgat
    14581 agcacctgat ttatatacaa gtttaataaa tattaatacc aattattatt caaatgagta
    14641 ctaccctgag attatagttc ttaacccaaa tacattccac aaaaaagtaa atataaattt
    14701 agatagttct tcttttgagt ataaatggtc tacagaagga agtgacttta ttttagttag
    14761 atacttagaa gaaagtaata aaaaaatatt acaaaaaata agaatcaaag gtatcttatc
    14821 taatactcaa tcatttaata aaatgagtat agattttaaa gatattaaaa aactatcatt
    14881 aggatatata atgagtaatt ttaaatcatt taattctgaa aatgaattag atagagatca
    14941 tttaggattt aaaataatag ataataaaac ttattactat gatgaagata gtaaattagt
    15001 taaaggatta atcaatataa ataattcatt attctatttt gatcctatag aatttaactt
    15061 agtaactgga tggcaaacta tcaatggtaa aaaatattat tttgatataa atactggagc
    15121 agctttaact agttataaaa ttattaatgg taaacacttt tattttaata atgatggtgt
    15181 gatgcagttg ggagtattta aaggacctga tggatttgaa tattttgcac ctgccaatac
    15241 tcaaaataat aacatagaag gtcaggctat agtttatcaa agtaaattct taactttgaa
    15301 tggcaaaaaa tattattttg ataataactc aaaagcagtc actggatgga gaattattaa
    15361 caatgagaaa tattacttta atcctaataa tgctattgct gcagtcggat tgcaagtaat
    15421 tgacaataat aagtattatt tcaatcctga cactgctatc atctcaaaag gttggcagac
    15481 tgttaatggt agtagatact actttgatac tgataccgct attgccttta atggttataa
    15541 aactattgat ggtaaacact tttattttga tagtgattgt gtagtgaaaa taggtgtgtt
    15601 tagtacctct aatggatttg aatattttgc acctgctaat acttataata ataacataga
    15661 aggtcaggct atagtttatc aaagtaaatt cttaactttg aatggtaaaa aatattactt
    15721 tgataataac tcaaaagcag ttaccggatg gcaaactatt gatagtaaaa aatattactt
    15781 taatactaac actgctgaag cagctactgg atggcaaact attgatggta aaaaatatta
    15841 ctttaatact aacactgctg aagcagctac tggatggcaa actattgatg gtaaaaaata
    15901 ttactttaat actaacactg ctatagcttc aactggttat acaattatta atggtaaaca
    15961 tttttatttt aatactgatg gtattatgca gataggagtg tttaaaggac ctaatggatt
    16021 tgaatatttt gcacctgcta atacggatgc taacaacata gaaggtcaag ctatacttta
    16081 ccaaaatgaa ttcttaactt tgaatggtaa aaaatattac tttggtagtg actcaaaagc
    16141 agttactgga tggagaatta ttaacaataa gaaatattac tttaatccta ataatgctat
    16201 tgctgcaatt catctatgca ctataaataa tgacaagtat tactttagtt atgatggaat
    16261 tcttcaaaat ggatatatta ctattgaaag aaataatttc tattttgatg ctaataatga
    16321 atctaaaatg gtaacaggag tatttaaagg acctaatgga tttgagtatt ttgcacctgc
    16381 taatactcac aataataaca tagaaggtca ggctatagtt taccagaaca aattcttaac
    16441 tttaaatggc aaaaaatatt attttgataa tgactcaaaa gcagttactg gatggcaaac
    16501 cattgatggt aaaaaatatt actttaatct taacactgct gaagcagcta ctggatggca
    16561 aactattgat ggtaaaaaat attactttaa tcttaacact gctgaagcag ctactggatg
    16621 gcaaactatt gatggtaaaa aatattactt taatactaac actttcatag cctcaactgg
    16681 ttatacaagt attaatggta aacattttta ttttaatact gatggtatta tgcagatagg
    16741 agtgtttaaa ggacctaatg gatttgaata ctttgcacct gctaatacgg atgctaacaa
    16801 catagaaggt caagctatac tttaccaaaa taaattctta actttgaatg gtaaaaaata
    16861 ttactttggt agtgactcaa aagcagttac cggattgcga actattgatg gtaaaaaata
    16921 ttactttaat actaacactg ctgttgcagt tactggatgg caaactatta atggtaaaaa
    16981 atactacttt aatactaaca cttctatagc ttcaactggt tatacaatta ttagtggtaa
    17041 acatttttat tttaatactg atggtattat gcagatagga gtgtttaaag gacctgatgg
    17101 atttgaatac tttgcacctg ctaatacaga tgctaacaat atagaaggtc aagctatacg
    17161 ttatcaaaat agattcctat atttacatga caatatatat tattttggta ataattcaaa
    17221 agcggctact ggttgggtaa ctattgatgg taatagatat tacttcgagc ctaatacagc
    17281 tatgggtgcg aatggttata aaactattga taataaaaat ttttacttta gaaatggttt
    17341 acctcagata ggagtgttta aagggtctaa tggatttgaa tactttgcac ctgctaatac
    17401 ggatgctaac aatatagaag gtcaagctat acgttatcaa aatagattcc tacatttact
    17461 tggaaaaata tattactttg gtaataattc aaaagcagtt actggatggc aaactattaa
    17521 tggtaaagta tattacttta tgcctgatac tgctatggct gcagctggtg gacttttcga
    17581 gattgatggt gttatatatt tctttggtgt tgatggagta aaagcccctg ggatatatgg
    17641 ctaaaatata tgtttgataa aaaattattc ctgtgctact aagaaattat ttttatataa
    17701 taaatattga gatttaatta aaagtcatgt gttattgtaa tacatgactt ttagttaaaa
    17761 tttttctatc atttaataat ctattattct tgactatttt ataataaaat tcatatatgg
    17821 aaatattaat actaaataat taatagttga taaaaaatag ataatatgct aaaagcaaaa
    17881 actaatttag agccttgtaa ctgtttattt gcaattataa aaacatcttt aaacatattg
    17941 actataatat aaaatattaa ctataataca aaacaatatt aattaatttt ctctacagct
    18001 atccctggta tagttatatt tccacccata gttgattcat aagttatagt tccagcactt
    18061 atacctctta tagttatgta atcatcctct aatactcttg aaggagttat tgatttttta
    18121 taactacata gtacaacctt atcataattt ccagacacag ctaatcttat ttgcacctca
    18181 tcaccatctt caataacttg aataacctta ccttcaaatt ttaccttttt gtacttataa
    18241 tcatcaggtg ttctagctaa ttggtcataa gtaataccag tatcatatcc tttcttctcc
    18301 tcttcttctt ttttgcgttg ttcttcagcc tttttagctt cttcagcttt tttagcttct
    18361 tcagctttac gttgattttc agcttcaata gctttctttt cgtcgtcttt cattttgaac
    18421 catggttcag catcagacaa tttgctattt aaagtttcta tttctgtttt ttgagaatct
    18481 ataactgatg tttggttaga aatgacctcc tcatggtctt cagaacaagc tggtgaggat
    18541 atattgccaa aaaacacgcc taaaataaat gccagtagag caataccctt tgtgctctta
    18601 aagaatttaa ttattttctt agagcttcct tttccttcat tactaaattc gttaccctca
    18661 ttttttttag aaaacataat acaatctccc ttttattaga tatattttat tttaaaagtt
    18721 aaaaacttaa aataactagt tgactaaaaa ttatatattc atattttcct aaaatatatt
    18781 tcccctaagc ataattttac aaaataaagt gagaagattc aatatatttt gaaaaaataa
    18841 gataaaaatg tcagattata atataatttt cttgaaggtg aattttatat attaaattaa
    18901 acataaagta ttttatttgt ataaaactat attatgatgt aattaagtga ctcagtgatt
    18961 tagaggtggt aaaatatata tatatgaaag agcataaata aattgatata ataaaaaatt
    19021 aaatattaaa tattaactat aataaaaaaa tatctggtaa taggtataat ataaaaagaa
    19081 tataccagaa agaaggtgaa gtatgggaga actacaaaaa attccagggg tagggaaagc
    19141 aacagaaaaa tctttaatca tgttaggata tacaactatt aaatcactta aagatgcaaa
    19201 cccagcacaa atgtatgaaa aggaatgttt aatgcgtgga cagcacatag acagatgtca
    19261 gttatatgta tacagatgtg cagtatattt tgcatcaact gaaaatccag aaccagaaaa
    19321 attaaagtgg tggtattgga aagattaaaa aatcaaaaaa gttagacata aaaaagagtt
    19381 gaatatccgt tttaaataat aaaaactaat actcaactct tttttagtcg taaattttat
    19441 gtaaatctat ttgtatggct aaatataccc atcaataaat gtataaatat accaatcaac
    19501 aaatgactaa acatactacc taacaaagga ttaaataaat tacttaacaa agcattttaa
    19561 aacaattaat tagaaactgt ttcttcaagc cattttctac attgctcaat atttaccata
    19621 gggtcaaaac cttggtcttt tcccttattt aaaagcatat cacaagggaa agtatcacat
    19681 tcaccacaat gattaagttc cttactttca cagcaagttt taaccttaca ttctccaccc
    19741 caaaatggtt tttccatagt tgggcaacca gtgcaattta cttgttcttt ttttgtacaa
    19801 ctgtcacaac agacaccaca tcttgattca aacatgttca aacatccttt ccattattta
    19861 aaaatattat aaaatgattt tagatgaata caaaagtgca aatagttgat tttaggtcat
    19921 ctaaatgtta aacataaagt tattagtact ggtaaattta taaaaactat tccaaaaatc
    19981 tttttgaata tttcaaaaca caataaatta cttcaaatcc ccttgaatat attttacagc
    20041 attatagatt gctttaaatc tctttgaata ttctacaaga ctatagatta gtttaaatcc
    20101 ctttgaatat ttcaaaacac catagattac tttaaatccc tttgaatgtt ctataacact
    20161 ataaattact tttaactttt atataaccat aaagttttta tctggcactt taaatggagt
    20221 tttatatcaa atttgccttc catcgaataa ccaaacttaa tttaattaca cattccaaga
    20281 gtcaaatatt cattcaatat atttgataat tctatgttat agctataatt aaatatagat
    20341 tattaaagtt aaatatttat ttaatatatt gaatgatttt ttacctatat ttaattaagt
    20401 ttcattatat aatataaaaa ttgtttttgc attaagtttt aatataatac ataataattt
    20461 taaataataa cattattata tattttttaa ttttaggagt atatctatta tatagcgagt
    20521 agataaaaca tataaaattc aaataaaaga tatatatttt taaataaaat ggatatagat
    20581 ttcaactaaa aagaatataa atttcaaacc caaaaatatc tagcatttac cattaagaaa
    20641 taacatcatt ctttctaaaa tttctattgg caatttcaga aaatactata gtagtaataa
    20701 atgcaacaca tattgtaact atagtgtcat taacatttaa agcagattgc tttataaccc
    20761 ccatagcact acctaacata gaataaggga aaaatatacc aacagcaggt tttgctacta
    20821 ttaatcccat accaaataga gaaaggcaaa gactaatacc aataggagtt gcaaaacttc
    20881 taatctttat agacatgtat aattgtatag aagctattga aatagaaata atccaacctt
    20941 tagcaatcca accagtcaat tctttaggta cactaccaga aaaaccaaac atatttcctg
    21001 caactatata aaagataaca aagaaaactt gtgtaatagc tgtaagtatt gaaactactg
    21061 taagtttaga taaaaagata ttttttaaat taactggcag tgtcattaca ttattccaat
    21121 tatgattcat atgttcaagc ctacaaatat atgcacaaaa gattgcgatt aagataggaa
    21181 agaaaaattc cccataaaaa agactaactt gagtccataa gctgtaccat tcttttttga
    21241 gtatgccttg atttagataa aaattaccag aaccaatcaa cacacttata agtggcaaag
    21301 ctaataatac ataccatata aaagaatttt ttaactttag aatttctccc aagactgact
    21361 tccttaacat ttaaatccct cctatacttc tttttttaat aaatgatttc ttccaatata
    21421 ataaattagc attccaatta agaaaactaa aatcgtaata gaaaaattca tatcaattct
    21481 atagacagat gaacctaaaa cattatcata agcataactt aaaggtgata actctaggta
    21541 ataagaccat ataaacaatc tacgaatacc ttgataaaac aaacctgatg tcaaacctat
    21601 aaaactacca atcatgccaa atgtaattgc aatcatttga tttggaatta cagttgcaat
    21661 ccataggtgt agtgcaatga tagcaatact tacaagaatt gttcctaatg tgtattttaa
    21721 aagtaaagat acagaaattg actcaataac ccctctaaaa tgtccaaaca acacaataga
    21781 taacacttgc atcaatacag gtatagatac caaaatagca gaacataaaa atttagataa
    21841 ataaatacta tttaaagatg tcacagaaga ttttaaaagc ttccatgtat ctcctttatg
    21901 ttctatatca cttatacgtg atgtaattat tgatattaag ataggaaaga atagaccatt
    21961 taaacttgca aaactcataa gcatatagga atattcaaat ccacctaaca tatctggatt
    22021 acgtgtaata gccctatttg aatttacgat acaccacatt atttcaacag ctacaaataa
    22081 aaaggtcatc agaataatct tctttctttt aagtttataa aattctagac caaggtattt
    22141 cattataaag tcaccgcctt accagtaagt tctaagaata tatcttccag gcttttttta
    22201 tgttcttcta ttctaaatac atctatattt gaatggacaa gcataccatt tattttagcc
    22261 acatctgagt cttttaaatt ttcaatagtc aagtacccat cttgtataag tgacatatat
    22321 cctttagtat ttaatagttt ttgtgcagat acaacattct tagttttgat agcaatctga
    22381 ctttgacctc tattatgaag ttcttttatg ctatcttgaa aaaccagttc gccatgattt
    22441 attattccta ttgatgtggc aatttggtca atttcactta aaagatggct agagattaga
    22501 acagtcatcc cgtatttttc tggtagagat tttattaatt ctctaatttc ctcaatccct
    22561 gctgggtcga gtccatttgt aggttcatca agtattaata atttgggaaa cttcattatt
    22621 gccatagcaa tgccaagacg ttgcttcata cctaaagaat attgactaac ttttttattt
    22681 ttttgatttt ctaaccttac aatttttaat gcttcattta catttttttt aggtaaatct
    22741 aagagtcttt gcattatggt catgttttca agccctgtaa gatgaccata gtatgatgga
    22801 gattctatca aagaacctat atcttttaaa attgatattc tatttttttc atttaactct
    22861 ttacctaaaa tattaatatt tccttgtgtg ggtttagcaa gtccaagaag cattttaaga
    22921 gtggtagatt ttccagctcc attaggaccc aaaaaaccat atacagctcc ttgtggaact
    22981 cttaggtcta tatcctttac tctaaatatt ttattgtatt cctttgaaag tctttgtgtt
    23041 ctaattatca tttccatatg tttcatcccc ttttttaatc tgtgcttatt gattctttta
    23101 acttatatca gtataataac ttggttacat ttcaattagc tgaaatttac cttacaataa
    23161 ccttaaaagt ctatttaggc aaagttgtga aaatgggtat atggtatact aaaggagggt
    23221 gatgattatg gagtcaataa aagataaaaa aatacttgtg gttgatgacc acaaggaatt
    23281 attaaaaatg atagatgaaa tcctgagaaa agagggattt agtagagtat ttttagcatc
    23341 aagttatgag gaagctgtta gggtatttag aaatgtaaag ccagattgtg caattttaga
    23401 tgttgtattg ccagatggag atggtttttc tattatgaga aaaattagag agacatctaa
    23461 aataccagtg atttttctct ctgcaagagg tgaagatgaa gatagattga ttggtttggg
    23521 cttaggggct gacgattata tagtaaagcc atttttacca aaggaactta ctttaaggct
    23581 tgtgggtata ttaaatcgtg tatatgtgcc tatagaagaa gaggagttgc cagtatttaa
    23641 actgggagat tctgttgttg tgaatttaaa tagtgcatgt gttgagaaag atgggcaaga
    23701 gatttcttta acagctaaag agcattcgtt gcttttaaag ttgtatgaaa ataaagggag
    23761 aattgttact aatgattcac tatgtcaagc catttgggga gatgatatgt atggatatga
    23821 aaataccctt atggttcatg ttagaagggt tagagagaag atagaaaaaa ctccatctac
    23881 acctaaacat cttattacag taagaggtct tggatataag ttgatgatta attaatttta
    23941 gatattagaa taaaagaaat caagaggagt gatttaattt tggatagtgt aaagtacata
    24001 ttgaggcgat ttataggttc aagtatcttg atttcattac tttttattgt attaaatata
    24061 gcaggttttc ttctgttttc atatatgcta tttgtatcta aatactctga taatttagat
    24121 acaagtgata gcagagaaat aaaatcaaac ttgattatga ttgaagataa tttgatttta
    24181 agaaatggaa agtttatttt agatgattct agtaaggaag tactacataa aaataaagtt
    24241 tgggcaatgt taattgataa caatggagat agaatatggg gatttgattt accaaaagaa
    24301 attccaagtc attatacttt gacagatgta gcaaagtttt caaggttctt tttaaaggac
    24361 tatcctgtgt atgtatggga acatccaaat ggaatattag taacaggtta tccaaaagac
    24421 aagtacacta agtttaacct tacttatacg gttaaggaaa tagaacaatt tcctatgtta
    24481 ataataggta tgtttctggt taatgcaata gttacttttt taatagctct attcataggt
    24541 ttaaaaatgg tgaaatctat aaaaccaatt attactggca taaagcttat gtcaaaagga
    24601 gaaccagtac ttttacaaga aaaaggaata ctaagtgata tttcaaaatc tattaatact
    24661 gtatctaaag agttgcaaat gaaagatgaa aaacttagga agaaagagga agctaggtct
    24721 aactggattg caggaatatc tcatgatata agaactccac tttcaatgat aattggatat
    24781 gctggagaac ttgaagaaag cagtagcctt tcaaatagag aacaagagca agtgtctatt
    24841 atatgcaatc aagggattaa aatcagagaa ttagtaaatg acctcaattt agtgtctaaa
    24901 cttgaatata atatgcaaac attgaattgt gataagatta gagtttctgc gtttttgaga
    24961 gagcttattt ctgagtttat aaataataat ttggataatg acttttacgt tgaacttgat
    25021 atactaaatg aagatattat tatagatgca gataaaaaat tattaaaaag ggctattagt
    25081 aatttaatac aaaatagtat aactcataac caacaaggat gtaatataag ggttacctct
    25141 aagtctgatt tagatttttg ctatataatt gttgaagatg atggaaaagg tatgagtcaa
    25201 gaaagaatta atagtttatt aaagagcaaa aatggactaa gtgaggcata tgccaaaggt
    25261 caaaatcatg gtctaggtat tttgatagta tctggcatta ttaatgcaca tagaggtaaa
    25321 ttagatatta cgagcattga tagtcaggga ctaaaaacaa tactaaaatt acctctaatt
    25381 aagtgatatt ttataaaata ataacagata agaatgaaga atgaaaatat tttgaaaata
    25441 attttattct ttattgacaa attaactcta ttagagtaga ataaggataa attcttttct
    25501 tgtcaagttt tattaaagta aagagtaact tgtgctttat gcgcttatgg ctgagttact
    25561 catggtatca aaattttcat agaaataata ttttggaatt attgtaaggt tattaaattc
    25621 tttagataat tccatttttt ttatttttta gttaatattt aattttatta ttgacaaaaa
    25681 aattctacta aaatagaatt atggtatagt gttttttaat tttaagaaaa aatataatga
    25741 catcctaaaa aagttttaat tatacgctgt tctgtgtagt tataatagct tctatgtaac
    25801 tattgtaagt atattttatt atagttattt atttaaagta cgataaatgt tttaaattga
    25861 agtattttgc gccgttgagt tctactaaag tagagttttt gtgtagtatt tttagaaata
    25921 acatatatat atatgtattt atgttgaaat atatgggaaa tttataatat aattaatgaa
    25981 aaaatttaaa ctttgtaata tataaataaa aaaactctaa aatagaagga tataattata
    26041 tagaatgttt taattaaaca agtcaaaaac tataatctta aaattaacat taacattatt
    26101 cttaagaagt aagaaattta agaagtaaaa agtttagtaa taattcatag caagtaagaa
    26161 atttagaaag taggaagttt agtgataagt gttagtaagc aagaaattta gtaagtgaga
    26221 agtttagtga taagtgttag taagcaagaa atttagaaag taggaagtct agtaataaat
    26281 tatagcaagt aagaaattta gtaattgaga agtttagtaa taagtcgtag taagtaagaa
    26341 atttagaaag taggaagttt agtgataagt gctagtaagc aagaaattta gaaagtagga
    26401 agtttagtaa taatttatag caagtaagaa ctttagggag taggaagttt agtaataatt
    26461 tatagtaagt aagaaattta gaaagtagga aatttagtaa taatttatag taagtaagaa
    26521 atttagaaag taggaaattt agtaataatt tatagtaagt aagaaattta gaaagtagga
    26581 agtttagtaa taatttatag taagtaagaa atttagaaag taggaagttt agtaataaat
    26641 tatagcaagt aagaaattta gaaagtagga agtttagtag taatttatag taagtaagaa
    26701 atttagtaag tgagaagttt agttataatt tatagtaagt aagaaattta gtaagtgaga
    26761 agttcagtaa taagttgtag taaataaaaa gtttaggaag taggaagttc agtaataagt
    26821 tgtagtaaat aaaaaattta ggaagtagga tttactgaaa tacaaatatt taaaatcaaa
    26881 gagtttaaaa gaaaggagag ctactggaca agtatccaaa atagatagct gagtacaaaa
    26941 tatttcataa aattaagcaa tataatacaa gagaattttg acattattta tatatattta
    27001 ccgtgtacaa atagctaaat ttaggattaa gattgaaaaa tatcttataa gtctgagctt
    27061 atataaatcc gtataagatg tatttaatcg aaaaatttta ttatggatat tgcttgtcta
    27121 tattctgagt agcaaggttt tatcatgact ataaaaaagt tgccacaatc agaattaaag
    27181 ataatgaaat ttatatggaa atcagattcc aaagtaacat ctagagatat tgttttagga
    27241 atggagcaaa aatatcaatg gaaacaaacg acaactttga ctcttttatc tagattagta
    27301 gtaaaaagat ttctaaattc tcaaaagata gataaatata cgcattatga agttttaatt
    27361 aaagaaaagg aatacatagg agttgagaca agagattttt ttagaaatat tcatgattct
    27421 tctataaaaa gtttattgtt gtcattacat gaaaatatta atttgagcaa agatgatatt
    27481 ttacttattg aagagtggat aaaaaatcta aaagaagagg agaaagacgt ataagcaaac
    27541 gtatttctta tagcatcaat ataaagtgta tgtaagtgta tttatgtaat atattagtct
    27601 acttaagtaa tatgacaaat gattataagt ggattatgat actataatgt gaatctaaat
    27661 aaattaaata aaaattaata gtggatattc tatttaatta aatttaaaaa gctaccttta
    27721 cttataagta taattaaggt agctttttaa atagaggtag tgtaattaaa gagaattttt
    27781 aaatataaat tgtgaagctt taatatagat gataatatat attttgcaaa tatgacacag
    27841 tgttttcgta tttaagatga taaaataaat aggaattaat gaagatattg aaaaaataaa
    27901 aataaaggat taatataaga tattaaagag atagagataa aagtgttaac agaagatatt
    27961 gaaaaaataa aagattgata taagatactg aagaggtaga aacaaaagt
//
LOCUS       DAEPUT010000049        27992 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.051, whole genome shotgun sequence.
ACCESSION   DAEPUT010000049 DAEPUT010000000
VERSION     DAEPUT010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27992
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.051"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            130..1758
                     /gene="aspD"
                     /locus_tag="KRL22_002309"
     CDS             130..1758
                     /gene="aspD"
                     /locus_tag="KRL22_002309"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HBH1272796.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFIGKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
     gene            1879..2874
                     /locus_tag="KRL22_002310"
     CDS             1879..2874
                     /locus_tag="KRL22_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBH1272797.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(3063..3446)
                     /locus_tag="KRL22_002311"
                     /pseudo
     CDS             complement(3063..3446)
                     /locus_tag="KRL22_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      3672..3769
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     repeat_region   3911..4202
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3911..3939
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(4488..4646)
                     /locus_tag="KRL22_002312"
     CDS             complement(4488..4646)
                     /locus_tag="KRL22_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272798.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     gene            complement(5005..6375)
                     /locus_tag="KRL22_002313"
     CDS             complement(5005..6375)
                     /locus_tag="KRL22_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HBH1272799.1"
                     /translation="MKLKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALI
                     ADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            6658..6756
                     /locus_tag="KRL22_002314"
                     /pseudo
     CDS             6658..6756
                     /locus_tag="KRL22_002314"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            6775..7196
                     /locus_tag="KRL22_002315"
                     /pseudo
     CDS             6775..7196
                     /locus_tag="KRL22_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7427..7699
                     /locus_tag="KRL22_002316"
     CDS             7427..7699
                     /locus_tag="KRL22_002316"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1272800.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(8017..8685)
                     /locus_tag="KRL22_002317"
     CDS             complement(8017..8685)
                     /locus_tag="KRL22_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH1272801.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFGEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(9520..11940)
                     /locus_tag="KRL22_002318"
     CDS             complement(9520..11940)
                     /locus_tag="KRL22_002318"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBH1272802.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            complement(12294..12644)
                     /gene="rsfS"
                     /locus_tag="KRL22_002319"
     CDS             complement(12294..12644)
                     /gene="rsfS"
                     /locus_tag="KRL22_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBH1272803.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            complement(12761..13333)
                     /gene="yqeK"
                     /locus_tag="KRL22_002320"
     CDS             complement(12761..13333)
                     /gene="yqeK"
                     /locus_tag="KRL22_002320"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBH1272804.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINSIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            complement(13334..14023)
                     /locus_tag="KRL22_002321"
     CDS             complement(13334..14023)
                     /locus_tag="KRL22_002321"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBH1272805.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            14299..14937
                     /gene="recX"
                     /locus_tag="KRL22_002322"
     CDS             14299..14937
                     /gene="recX"
                     /locus_tag="KRL22_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBH1272806.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            15090..17093
                     /locus_tag="KRL22_002323"
     CDS             15090..17093
                     /locus_tag="KRL22_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HBH1272807.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMEHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDSSI"
     gene            complement(17220..17531)
                     /locus_tag="KRL22_002324"
     CDS             complement(17220..17531)
                     /locus_tag="KRL22_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBH1272808.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(17609..18427)
                     /locus_tag="KRL22_002325"
     CDS             complement(17609..18427)
                     /locus_tag="KRL22_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1272809.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSQLFAKKLEESLNPIQSVEKIVLYLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFSGENKTIKENIKYSYL"
     gene            complement(18527..19051)
                     /locus_tag="KRL22_002326"
     CDS             complement(18527..19051)
                     /locus_tag="KRL22_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1272810.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            complement(19070..20212)
                     /locus_tag="KRL22_002327"
     CDS             complement(19070..20212)
                     /locus_tag="KRL22_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH1272811.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKVPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            complement(20492..22879)
                     /locus_tag="KRL22_002328"
     CDS             complement(20492..22879)
                     /locus_tag="KRL22_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1272812.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKSDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            complement(22872..23555)
                     /locus_tag="KRL22_002329"
     CDS             complement(22872..23555)
                     /locus_tag="KRL22_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272813.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVMLPIGLDGREVDEPFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VLKVGDKND"
     gene            complement(23672..24982)
                     /locus_tag="KRL22_002330"
     CDS             complement(23672..24982)
                     /locus_tag="KRL22_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1272814.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            complement(24976..25683)
                     /locus_tag="KRL22_002331"
     CDS             complement(24976..25683)
                     /locus_tag="KRL22_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1272815.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            complement(25988..27829)
                     /locus_tag="KRL22_002332"
     CDS             complement(25988..27829)
                     /locus_tag="KRL22_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HBH1272816.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVED
                     IKIENKSARLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFNNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPILKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSSRESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
BASE COUNT         9419 a         4529 c         3277 g        10767 t
ORIGIN      
        1 tagagttatt attttaattt catactttac tttttctata aacctattat aattaaagta
       61 taatcatttt tgcaacttgt ttattttatt ataaaaatgt gaaacttatt acataaggag
      121 gaatttaaca tgaaaaatca tacttataaa gaaatcaaaa acatatatgg aaaaataagc
      181 ccttttgaat ttaaggacaa attaatagat attgcaaaat acactgcaaa agaaaataac
      241 agagaattac ttgatgcagg tcgtggaaat ccaaactgga cttgttcaac tgctagagaa
      301 gcctttttta cttttggtca tttcgctatt actgaaactc gttctaattg ggatttaggt
      361 catttggctg gaatgcctca aaaaaagggt attaaagaaa gattttttaa atttataaat
      421 gaaaatatag atatgcctgg agcatattta gctagagata ttataaactt tggtataaat
      481 gaacttggat ttgatggaga tgaatttgtt catgaactag ctgatggaat tattggtgat
      541 aactatccac ttccagatag aatgttacct catatggaaa aaatagtaca cgattaccta
      601 gttcaagaaa tgaaatatga tatatcaggt aaatatggtg atgtagaaat ttttgctgtt
      661 gaaggtgcta cagctgctat gtgctatata tttgattcat taatggcaaa tgaacttcta
      721 aaaaaaggag ataccatagc cttaatgact ccaatattta caccttatct tgaaatacct
      781 aaccttcctc gttacgactt taaagtggta aatataaatg ctaatgaagt tgatgaaaaa
      841 ggtgctcata catggcaata tacaaaaaaa gaattagaga aacttcgtga caaatctatt
      901 aaagctttat tcgttgttaa tcctaataat cctgcttcta tagctatgga tgaaacatct
      961 tgtaataatc taatagatgt aattgaaaat tataataaag atttaatgat aatatcagat
     1021 gatgtatatg gaacttttgt agaagatttt tcatccttaa tgtcaaaact accttacaac
     1081 actgttggag tatattctta ttcaaaatat tttggagtta caggatggag acttggtaca
     1141 tttgcccttc ataagaaaaa tgtttttgat aagaaaataa atgatttaac tggagaatta
     1201 aaaaaatcag tagataagcg ttacagtgat atgagtctta acccttctag tctttccttt
     1261 atggaaagag ttgttgctga tagcagactt gttgctctca accatactgc tggtctttct
     1321 actccacagc aagtacaaat ggcgtttttc tctgcttttg cattgattga caaagtagat
     1381 gcctacaaaa aacttaatat gagtatctgc catagacgtc aaaaactatt atttgaagct
     1441 ttagagcttc caattaatga aaacaaaaac aatgctgcat attacactca atttgatatt
     1501 gaagaatggg ctaaattaaa ctacggagaa gacttattta aatttatagg taaaactgca
     1561 tctccagtag atgttcttta taaattagct aatgactatt cagtagtttt acttagtgga
     1621 aatggattct atggccctga atggtcaatt agaatatctc tagcaaatct atatgatgaa
     1681 gcttatacta agataggaaa agccataaga gagatattaa atggttatat cgttgaatgg
     1741 caaaaaatta agaaataatt atattacact gaaatatcta aattatatga ataaaagagt
     1801 ttatgtagac cttaactact ttttttgata taatcctatc ggaattataa attttattta
     1861 tgaaaggcag agaatagtat gagtattaag aaaaaagttg ccatagtttt tactggtgga
     1921 actatatcta tgacagtaga tgataaagtc ggagcagcta taccaacttt atcaggtgaa
     1981 caaatactat caatggttac caacattgat aaagttgcag atgttgaagt ttttaatttt
     2041 gatgaaattc caggacctca cataacacct tatagaatga tggaattgaa aaattatgta
     2101 aatgatttat tagcaagaaa agatattaca ggtgttgtaa taacacatgg tacagatagt
     2161 ttagaggaaa cagcttattt tctagacctt acaattgaca acatcaaacc tgtaatagtc
     2221 acaggtgcta tgagaagtag ttctgaactt ggatatgatg gttcaagtaa tttatctgca
     2281 tcagtttgta ctgcagtatc caaagatgct atgggaaaag gagtccttgt agttttaaac
     2341 aatgaagtat tattagcttc tgaagctact aaaacaaata ctctttctct aaatacattt
     2401 aaatctctaa ctagtggccc attaggaata attgactgca acgaacttgt ccttacaaga
     2461 gatattgtaa atagaacaat tatagatact gataaggtag aatctaaagt tgccttattt
     2521 aaagcatatg taggagaaaa tgctgacttt ataagatttg ctgttgatag tggttataaa
     2581 ggtatagtta ttgaggcaat gggcagaggt aatattcctc ctcaaatgct ttctggagtt
     2641 gaatatgcta gagaaaaagg acttcctgta gttatagttt ctagatgtca ttcaggtaga
     2701 gtattcgata gttatggtta ctttggttct ggtagagatt taaaaaatct tggttgtata
     2761 tttggtgggg acttaccagg tcaaaaagct agaataaaac ttatcttagc acttggaaaa
     2821 actgataacc ttgatgaaat caaagacttc tttgaaaaag gaatctattg ttaattctaa
     2881 taacttctat ttaattattt attgatattt caacattttt aaatcaaaat ctaatactta
     2941 tgtcagttaa atgtcagcaa aatattttat ccacaatttt tacacaaatt ttccacaact
     3001 tatccccaat attatccaca agaaaaaagg tagcacttat attagtagct accttttatt
     3061 tattaatctt catctttcca gctttttatc caatttccta tttctattat tttttcttca
     3121 gttatttctt ctccatcatg taattttgaa attagttctg ataatggatt gttatgtaga
     3181 cctccaaaaa ttctttttcc ctctattttg agatattctt tctcttttat taatactcta
     3241 tagtgtacat gtttcccaat tctctgcgat atgaaaaaac cttttttagt taatctagct
     3301 aaaagtgtaa ttgtagttgt atgcttccaa gcatatgttt tttctattta atctgcaaca
     3361 tcttttgata ttacagtttt ataaccagta ttccatatgt atttcataat ttttaattct
     3421 gcatctggta attttttatt caacataata tattccttct ttcaatttat gtcacttcct
     3481 caaacttatc tagcttaaat taataatagg agctttttat cacaaaaact acaggtaaat
     3541 ttttctatat attctacgta tttagtctgt ttttaagtgt gaaattacgt tcatacctat
     3601 aaatttattc aattttcaaa caatcttgtt gaataataac taattctatt gtattattta
     3661 gttatagaat aaaactaaat cggcaaaact agagaaatct agtgacgcaa agctataggg
     3721 actaagactt atataaatat cttatgagtt atgttagcca gttgccaaag agatattgtt
     3781 ctttttgttt ttatgaaagt tttttagggg gataataatt tatatgttta gagataaaat
     3841 ggataaatgt acacatatat tgactgctta tattagcaat tcgtatgatt attgtaattt
     3901 tttggataca atttacattc catatagtta atataaaact caattaaatt atgaccttgg
     3961 tttagatagt tcattattta cattccatat agttaatata aaaccagaag gaatatctgg
     4021 agttattgga gggtctattg gatttacatt ccatatagtt aatataaaac atttactaag
     4081 tgtagatata attataaata cgatttaatt tacattccat atagttaata taaaactttt
     4141 gtaaaagttt agaagtttat atataaaaaa aatatttaca ttccatatag ttaatataaa
     4201 accccaaaat aaattgagta tttccaatgc ctacacatat acaaatctct caaatttgca
     4261 gtgaaccatg agtagtgcaa ttgataacac ttatcacaag tcctcaatgc cttatatttc
     4321 aactgttaag ccttaatttc ttcaaaaaat cgaacactgc aaaatttcta tgactttatt
     4381 atatcataaa aatattattt ttgaatatct gtaccaattt gtgatataat aaaagcaaga
     4441 agaactacaa tctattttgc tgtagagtgg agttcataat ttagaaatta cttagtttta
     4501 tggaatctga tttttaaatc aaattcccaa ccactcttag ttgccgcttt gagtggtttt
     4561 ttacgctttc taaatagttt gctagctata taaactatta agctagcaga tagacttgct
     4621 agtatgcctt gtaaaaaatt atccatgtat attcacctcc cttcttagcg tcgggaggat
     4681 aattttttga tacatgaact ccactctata aattgtagat tacatcttct tgctaaaaat
     4741 attataacat ataattctta catattttac ctatttatta ctttttacat tataataata
     4801 ttcttttaat caaaaaaaca cctactatta aagtaaatgt ttttaagtat ttttaatttt
     4861 aaaatccata tagttcatat gaaactaaat ataataactc aacatatgag caatatcgag
     4921 acatttacat accacatagt taatataaaa cgaaaataaa aaaattaaac ttataaaacc
     4981 cttattaatt tacataccca ctagttattt atattcaaaa aaatcttctc catctgggtt
     5041 ataaaataat attctacttg ccaatccttg ttcatattta taattttctt tatcacctac
     5101 ataagaaaat gttaatgtca tgcttcttga tggatctaat gaaattatat ctaaataaat
     5161 agtacatttt tctcctggct ttaatacacc gaaactatta aaatccattt ttattttagc
     5221 atattgcccc atatataatg ttgaattagc ttctccataa acttttaatt ttgttacatc
     5281 taaattttgt gtacttgtat tttctatatt tataggaact gttgggtctt tatatttttc
     5341 agtataatat tcaaggttat catcataaca ttcaagataa cttcctttat cttgccaaat
     5401 tatgtgcttt gaatcaaaat caatctttaa tccacatatt atatttttat ttgaagacgg
     5461 aagactaata ttattgatgg tattttcaca ctctagcata attttatcac ttagatttcc
     5521 tatcccagtc acttttgcag catttttaag tatatcttta ttacttccaa tatcaactag
     5581 tacaatagga ttatttttag ccattggtga agcaactaaa gcataaacta aatcagtacc
     5641 actagctata taaaattctt ttgcgccatt atagaactta tttactattt ttttattagt
     5701 atcatatcta tctactccac ctaatctagt tgaattagta tcattaacta gtttgtcact
     5761 cattgatgaa gtaccaccta ttacataact ttctacacca gttgtattaa atggaacact
     5821 ttttccatca gttaatacta tagctgcttt atctctaact gctacaggtg cagcactcat
     5881 tgcatcaggc tctcctttaa aagcattagt caatataact ttatttactt tgttaattga
     5941 gtttatttct tttgcaacat tatagcttgt cttaattcta tcactacctt gaagtctttt
     6001 agcctctatt cctttatctt ttagaagagt ttctgttgct ttatcaatag aactttctcc
     6061 acctattatg tatacctttt tagctttctc tactctttta agagttgcat taggtatgtt
     6121 atttttctta gttaaaaaaa ttggtgcatt tgttgctcct gcaagtccac tcgcacttaa
     6181 tccatcagcc attgtgctgt ctgcattaat taatatagct gtagtataat tttgttcatc
     6241 agctataaga gcagccgttt catatttatc ttttccttga atagtataaa ttgtatcaag
     6301 tgcattagct gatataggac cagcagcaaa cattgacacg gctaacccta gtgataataa
     6361 tttctttaat ttcacaatat ctcccccttt tatatatgaa atactatata tcttacataa
     6421 ttctacatta aattttcttt tcctccttta acgatattta tcttcctgtt aatttaagtg
     6481 tatacaaata cgtgttataa tgtaactgta aagaattaaa aagataatga cataattaga
     6541 gcagtccaac tgttctttta taaaactaac ttataaaggg agcgtacata tatgaatatc
     6601 aaatcagctt ttataagaaa aagatgggaa aaattctatg tatatgtgga ataagaaact
     6661 ggcaaaaaga aacaaaaaag ttatggaagc tataaaaaga aaaaggatgc tgaaaaacat
     6721 ttaattgaaa taaagtctac tataaataat aataagtttg ttgctccaaa aggtatgaca
     6781 tttgtagaaa gatgttataa atatatagac atgaataaaa ataattggtc tccatatact
     6841 gttacaaata caaaatcttg ggttaaaaat tacatagaac cttttttaag aatctaaaac
     6901 tcacagaagt aaatcctagt tcagtacaag cttttgtaaa ttataacttt aataattcta
     6961 cctttactag tgctaaagta aggtatagct ttctaagttc tgtaataagg gaagcgtata
     7021 gattaagaga aatacaagaa aattcatgtg attttataaa acttccttct aaagaaaaat
     7081 attctacaaa tgaaatatac aatagagaag aagtattatt gctaatagaa aagttacttg
     7141 gtaataatat agaaatactt attcttttaa tgttacttct aggtttaaga atgtgagaag
     7201 ctattgggct taggtggtca gatgttgact tagataacaa tctgataaat gttaatcaaa
     7261 ttcttgtcta ttctaatggc aaaatatctt ttaaagagcc aaaaacacca aaatcaaaaa
     7321 gagctttatc agctccaaaa gaattaattg aaaaattgaa aattgaaaaa ctaagacaaa
     7381 gcaaattaaa attgtaaggt atcctggaaa acagaaataa cttagtttgt ctaaacacca
     7441 atttaaatcc gtttctacct tcttcactaa gaaaaacgtt tcacaatttt acaaaaaaaa
     7501 taatttaaaa aagattagaa tacatgattt aagatataca agtgccactc tgctgctttt
     7561 agggggaact aatatgaaag ttgtttctga aagattgggt catacagata taaaaataac
     7621 tatgaataga tattctcatg tacttaaaga aatggacaaa gaagcttccg acaatctaag
     7681 cgaacttcta tttaaatagt aaaaactgac tgtcagttaa atgtcagtta aacctaaaaa
     7741 aataggtttt gtcagttgat tatcagtcaa ttattttata atagtttcac ttaaaaacgt
     7801 ctatatctac acattttact atttgtttat gcttattaat atctatctgt tattattaat
     7861 tctaatagct tctatttaat tatttagttc agtttacagg aaactacaca caaaccataa
     7921 aataggatgt tgacaatata acagatagta tgctcctgta aaaggtaaca tagtatctgt
     7981 tatattgtct ggattcccaa attagctatt tggaacttaa ctaaaaaatc ctaatataag
     8041 ggcaactatt ataatggcaa tcggaataca tactgtgtaa tcctgttcca tagagtcatc
     8101 atctgaatgt agttttacaa ttcgcaattt agcaatcagt ttgaagcaga aatagcctat
     8161 tattgttcca attacgttcg tgagtaagtc gtctatatcg gttgctctgt gtaacgtaaa
     8221 aagctgaata gtttcgataa aaagagataa tccaaaacca atcaagaatg tatttctcaa
     8281 acgttcaaag gttttgctta taagcggaca taaaaaacct aatgggacaa aaagtaaaat
     8341 attcaaaata aaactcaaac taaatccatc actaaaagga ataagattta tgtttggatt
     8401 aaagaacgtt tcccctaact gtgacagtct tatatattca ccgaatgtag gtataccaac
     8461 aatatgcgat agtgttaaac ataagtagta atacattgcc agtgataaaa tagatgtttt
     8521 gacctttgga atatcactat ttttcttgaa tattacaact aagaaaatac caatcaagat
     8581 aattcccaac aagaaaatag gattaattaa caataaatct ttgatagctt caaacagact
     8641 gagttgaatt tctacacctg attgattatt tgttacagtc tccatttgta catacctcct
     8701 cataacattt caattatttc taaaaaacaa aatagaagat aaatcttaaa atcatcctat
     8761 caaaattttt aaatttgcct ttatcagttt ataccaccag ttaattcctg tcttacttct
     8821 gtatggtatt cttgggattc tttcatcaaa ttagacaaaa aatggttacc atatcaataa
     8881 actggttacg ctccatatct cccgaagcaa ccatcccctg agaataaatc cgtatcagga
     8941 atctccacat ctactgcacc tatcacaagt tatttgataa catcctcaga caatcccaac
     9001 ttggatatat cgacaacacc cattagaata ccactgctga ccatacttgt tttcctgctg
     9061 ataattttaa tcaactggga agttgaaacg ctatcttttt tacaagttcc tttttagaaa
     9121 catggtagct attatatgaa tctgaatttc gttgtctggg tgtttcatat aaagcataga
     9181 tatgcacctt ttttgcctgt tttcattata tagaaaaaat ttcaaaatac aataattata
     9241 tttttttcgt ttaagcttag agcagttcct tgacgaacaa cactttggaa actgaatgat
     9301 ttacatacca cttaatacat taactcgatt taacattaat tataataata tttaaaacaa
     9361 caactagggt atataagaat gaacttttta gttctttaat catttttttg tataaaatca
     9421 aatctatttt tataatttca acaatgaaaa aaggcttatc tctattttga gacagcctca
     9481 tttattttat aaatttatat ttttgttcat atttttgagt tatttaacaa ctatatttac
     9541 taatttttta ggtacagcta caactttaac tatagtttta ccttcaacta atccttttat
     9601 tttttcatct tctaaagcta ccttttccat ctcatcttta gatatatttg agttaacagt
     9661 taattttcct ctaacttttc cattaacttg tacaacaact tctatttcat cttttactaa
     9721 agctttttcg tcatatttag gccagtctat atcaaataca cttccttctt tacctatcat
     9781 agtccatagt tcttcaccta aatgaggggc aaatggtgca attatagtta ctatagtttg
     9841 tacaccttct tttataactg cttcgtttat attatctaac tctttatatt tatacatatc
     9901 atttattaat tccataagag ctgatatagc agtattaaat ccgaattttt cacttaaatc
     9961 agcagtaact tttttaagtg tagagtgtat agtatatctc atatccttat cttgggaatt
    10021 taattctcca aactctacat cctttttaac cacatctgct aactcgtcaa ccaatctata
    10081 aaccctattt aagaatctaa agcatccatc aacaccttgc tctgaccagt ccaaatctct
    10141 ttctggtggt gctgcaaata atacgaaaag tcttgcagta tctgctccat actcatctat
    10201 tatatccata ggagatactg tattcccttt agacttactc attttagaac catccataag
    10261 taccattcct tgagtaagta agtttttaaa tggctcattg aagtctacca ttcccatact
    10321 cttaaatgcc tttacaaacc atcttgcata aagtaaatgc attatagcat gttctactcc
    10381 acctatatat tggtctactg gatgccatct attaactaat tccttactaa atggttcatt
    10441 ttcattattg ctatccacat atcttaagaa ataccaagaa gaatcaacaa atgtatccat
    10501 agtatcaact tcccttctag ctggttttcc acagtgagga caagttgttg acataaattg
    10561 ctttgaagtc gtaagtggag attccccttt tccagtaaat tcaacatctg ttggtaaaag
    10621 aactggtaaa tcttcctttt taactggaac tattccacat tcatcacaat aaaccacagg
    10681 tataggacaa ccccagtatc tttgtcttga aactaaccag tctctaagtc tataattaat
    10741 tgttctcttt cctctacctt ctttttctaa cttatcgatt attccttcaa atccttctga
    10801 agcatctaat ccattaaatt cttctgaatt tatcattttg ttatcttctg ttattacatc
    10861 aattatgtct aaattatatt tttcagcaaa atctctatct ctttcatcat gtgctggaac
    10921 tgccattata gcacctgttc catactcaac taatacatag ttagctatcc atagaggaac
    10981 tttcttgcca tttaaaggat ttataacata tctacctata aacattcctt ctttttctac
    11041 atcagctgct gttctttcta tttctgtcat agtatgcatt ttttgaacaa aagcttcaac
    11101 atctgcttca tattcagtcc ctgcaaccaa ttctttaact aattcatgct ctggagcaag
    11161 taccatataa gtaactccat aagttgtgtc tggtctagtt gtaaatactg tcatagattt
    11221 atcagttcca tctatatcaa aaactaaatc tgctcctgta cttttaccta tccaattttt
    11281 ttgcattgtt ttaacttttt ctggccatcc atctaatgta tctaagtcat taagtaattc
    11341 ttctgcaaat tcagtagtct taaaatacca ttgttctaaa tctttcttta atactgttgc
    11401 tttacatctc tcacatgctc cttgaacaac ttgctcattt gcaagaacag tctcacaaga
    11461 aggacaccag ttaacatatg attttttctt atatgcaagc ccatgctcta aaaacttcaa
    11521 aaatatttct tgtgtaaatc tatagtattc tggcgttgaa gttgcaactt ctttatccca
    11581 atcataacta atacctaata aatttaattg ctctttcatt tcttctatat tttccattgt
    11641 ccatttatgc ggatgtatcc catgttttat agctgcattt tcagctggta atccaaaaga
    11701 atcccatccc attggatgaa gtacattata tccttccatt tttttgaatc ttgcgacaac
    11761 atcacctata gaataatttc taacatgtcc catgtgtatt tttccagatg gataagggaa
    11821 catttctaat gtgtaataat taggtttttc agtttgtgca gtatccattt tatactgatt
    11881 attatctttc caaatttttt gccatttcga ttctacttct ttaaaattat atacgctcat
    11941 attttgcctc ctatttttaa ttgtgtataa ctaccttatt tagtattatt tacttataat
    12001 ttccaaataa ttctttgaaa ataaaaaatc ctcgtcacta aacttacgtt tagggacgag
    12061 gataaatctt cgcggtacca ccctaattag cctactacat atatagactc tcttagatag
    12121 cttttaatcc agccatggag aatagatttt aatctagtaa gttcaaagtt atataatatt
    12181 agttctcacc ttccactaac tctctgaaaa aatataatct tttactgctc tagtctattc
    12241 aatttaatat aatttttgaa attttctaat tataataaca tatattatca tgtttatgct
    12301 aatgtgtcaa tatctatata aggtgcatct ttccataatt tttctaaatt ataaaaccct
    12361 ctattttcct cattaaatac atgaaccatt atgtctccat aatcaaggag tacccaagtt
    12421 tgagttcctt gtccttcttt acctcttggc tctaatccta gttttgctaa ttcatcttcc
    12481 acattgtcag caatagcttt tacctgtctc tgagaagatg ctgtagtaat aataaaataa
    12541 tcacacaaac tagaaacttt tcctatattt attataactg tatcttgacc cagtttatct
    12601 tctatggcat catatgctat ttttgtcatt tgttccactg tcatataaaa attcctcact
    12661 ttcctaatta aaatacactt agttattgta acatattaat acgattttgt aacatagtca
    12721 aatttaaatt tattaatatg tttgccttta tatagctttt ttataataac ttttctttaa
    12781 ttagatagtt tcttgccata actgttcttg gatgtatctc ttctttttta ttgatgacaa
    12841 acattaaagt attattaaaa gaagttaaaa gtgcttcatc aagcttccct ccatatgcta
    12901 attctcttaa tgtatctaca actgggaatt ttcttccttc ttcaattaaa tcagctatgt
    12961 aaattatttt ttctaaaaga gacatgtcct ctctccctgt tgtatgatat ttgattgaat
    13021 ttataatatc ttcatcttct acttcaaatt catactcgca tatgtacgcc ccaattacac
    13081 tatgagacaa ggaacgattt ccatcctcta ttgggtctaa atatatttca tacttattta
    13141 cataatcctc tatttccttg tcacttaaat actttgcaca atcatgaatc attcctgcta
    13201 agtaagcttt ttctttgtca catccataaa tctcacataa tttttcagca cattttgcaa
    13261 cattttttga atggctaagc ctccccactg gtagcatttg atttagtctt tggttaatat
    13321 tttctaagtt catttaatca tctccatatt gatatagttt attttcatat aaataatttt
    13381 ctacattttc gggtactaag taacgtattg acttgccttc atttagctgt tcccttatat
    13441 atgtggacga tatatccagt gatggaacat aaactgttat aatgtcagca ttatacttct
    13501 tagttagttt ttctatagtc tcttgtgacc ttaacaaact aattcctggt ctagttgcgg
    13561 ctataaaagt agctaactca aagtttttct ttacatcttt ccactcttca acactacaaa
    13621 ttgcatctgc acctgttata aaataaatgt ctgcattttt gtattttttc tttaagtatt
    13681 ttaatgtatc tattgtataa gtccttttct ttctttcgat ttctactttt gaaactaaaa
    13741 aatcttcgtt gctttcagtt gctagaagtg tcatattata tctatcatac ttatctgtag
    13801 tgatacataa tttatgtggt ggatttcctg atggtataaa gattattttg tcaatgtcat
    13861 acttgtctct aataaattct gctgttgcta aatgagcata gtgtataggg tcaaaagtac
    13921 ctcccaatat acctattttg attttgcctt tatggcgatt aaatttctct agtttttcag
    13981 tatttttcaa ctctgccatc ttaactagat tttcacttct catattttgt ctccttttaa
    14041 tgttataata ctattgtacc attatttttt atttcttaaa gcttataatt tgtttttttg
    14101 ggtatataat tatatttata tgctaaaaaa cactttaaaa aataattatt taacatgatt
    14161 ctgctttact ttttaataaa aataactttt tactattttg tcttaatttt gataaaatat
    14221 aacatacaaa tataagtttt ttgttaaatt ttattagttg cttttgttaa tataattaca
    14281 tataaaaaag gaggacttat gggtataatt acaaaaatag aacaacaaaa aagaaatgat
    14341 gatagagtta atatttatgt agatgataaa ttttttattg ctatatttaa agaacttgtt
    14401 tatacattta atttaaaaaa agggaatgaa ataaatgaag aagaattaaa acctatttta
    14461 gatgatgaaa tgtatataaa agctaaaaat aaagcattaa atattttatc tcatgctgac
    14521 caatctgaaa aaaaattaaa agaaaaacta tcatcagaat ttgatgaaaa tataattgag
    14581 agggtcatag attttcttaa aagttataat ctcgtaaatg acagtgtatt agctcaaaaa
    14641 attgttaaca caaatgttaa cctaaataaa tgtggcaaaa acagaattaa gcagaattta
    14701 tataataaag gtatcaatag aagtacaatc aatgaagcag tatctgaatt agacaaggac
    14761 actgaatttg aaaatgctat gtatctagca aaaaaaaggt atgaaagagt aaagaaagaa
    14821 gataaaaaga aaatatatca aaaaatttct caacatcttt cctataaagg ctttgattat
    14881 gatattatta aaagagtttt aaacaaactt ttaaattttg atgaatacga tatataagta
    14941 taaatactag ggaggtaaat tatgaaatta atcattggtg gcttaagctt tttattagga
    15001 ttatataata tatatcaatt atacagagaa gatagtatga gataaatatt attttttaga
    15061 tgtaatattt attatggagg agaaatacaa tgaaaagtca aaaaagattt aaaattttag
    15121 atattgatgt atacctacaa ccatttgaat ctgatataaa aaagcgaatg gaacattatg
    15181 aggatatgaa atcaaaaaca ttgaaaaact ataaagattt tagttctttt gcaaatgctc
    15241 atctttacta tggatttcat cagacaaatg atggattctt ctatagggaa tgggctccaa
    15301 atgcagatag tttgtcacta attggtgact ttaataattg gaatagaaaa tctcatcctc
    15361 taagaaaaat tgggtctggt aattgggaaa tatttattcc tggtcaaaat agcttacctc
    15421 acaaatcaga ggtaaaggta caagttactg caaatggaaa aacatttgac cgtataccat
    15481 tatatataaa aagagtaatt caaaaagatt ttggtggatt taatggacaa atatggcaac
    15541 caaaaactcc atttatctgg actgacaatg attttgactt aaaaaacata acttctccac
    15601 taatctatga atgtcatata ggtatgtcta ctgaaagcga atctattgga acttataatg
    15661 aatttactga aaaaatactt cctaagataa aaaaagctgg atacaatacc attcagctta
    15721 tggctattat ggaacatcca tattatgcat cttttggata ccaagtttca aacttttatg
    15781 caatctcatc taggtttggt actcctgaag acttaaaaaa cctcataaac actgctcatt
    15841 caatggggat tgctgtttta ttggatttag ttcattctca tgctgtaaag aatactttag
    15901 aaggaataaa tgagtttgat ggaagtgaac atcaattttt ccactcaggt tcaaagggaa
    15961 atcatcctgc ttggggtaca aaacttttta actatggtaa acctgaagta atacattttt
    16021 tgctttcaaa tataaaattt tggttaaatg agtaccattt tgatggcttt aggtttgatg
    16081 gtgtgacttc aatgttatat cataaccatg gtcttggagt ttcatttgat agttatgaaa
    16141 aatattttag tatgaataca gatattgaag ctataacata tctccaattt gcaaatgaat
    16201 taataaaaga aattaaacct aattcgataa gtattgcaga agatatgagt ggaatgcctg
    16261 gtatgtgtat ccctataaaa gacggcggaa ttggatttga ctatagactc gcaatgggag
    16321 tacctgattt ttggataaaa actatctcta acttatctga tgaagactgg gatttgggaa
    16381 aaatgtggta tgaacttact actagacgac ctggagaaaa aaatatagga tattgtgaat
    16441 cccatgacca agcattagtt ggcgataaaa caattatttt ttggctagct gacaaggaaa
    16501 tgtactggaa tatggaaata aactcaaata accatgttat caatagagca atatctctta
    16561 ttaaattaat taaattaata actttttctc tagcaggtga aggatatcta aattttatgg
    16621 gaaatgaatt tggacatcct gagtggattg attttccacg agaaggcaac aattggagct
    16681 ataagtatgc cagaagacaa tggagccttt cagaagataa caacttaaag tataaacaat
    16741 tattaaattt tgataaatct atgctcgaac ttacaaaata cagtgatatt tttatccaaa
    16801 atagtcatga acttatacat atggataatg ataaaaagat tttggtgtac agtaagggca
    16861 aatatttatt tatatttaat ttccacccta atctaataca atcagttgat atttcaaagt
    16921 ttcaaaatac aaactacaaa acgatattaa atactgatat ggtagagttt ggaggaaaca
    16981 caaaaaaaga aaacttaaga gattatgatg tatactttag ctcaactcct ccttcttcta
    17041 aaatgcctat tgcctctcgt acagcaatag tgcttttaga tagtagtatt taaggttggt
    17101 ttttctagta tataacactc atattaaaat aaacactaaa agccaaataa caatttaaat
    17161 acaaaatgtt atttggctaa tttagtttga tactatttaa ctatctttta cattaagttc
    17221 tataatttcc aacttttaat ttgtggtatt atattcatct taacagtttg attctttaaa
    17281 gcttttctaa atttctcagt tgaagaatct ttaaacattt tactagaagc actcttgagg
    17341 tcttctatag attcccaatg ttgtatcata atccactttt gagacttttc atcatataaa
    17401 agctcagtat caataaaacc agattgaata gaatgaaatt ttaattctaa gtcatttaca
    17461 atttctataa actcttcttt tgataaattt tcttccacat taaactcaac tatttctgta
    17521 ataattttca tatgtaaaac ctccaattta ttttcctata tcatatcaaa aaataaattg
    17581 gaggtattgt aaaaaatcga cagtataatt ataaatagct gtactttata ttttctttaa
    17641 tcgtcttatt ctcaccacta aatttaattg gtgacgtccc tgaaaatttt ttaaattctt
    17701 ttataaagtg tgcttggtca tagtactcat tttcataaat aaaatcaaaa agttcatcat
    17761 ctttataatt ataaataagt tgattgcttg ccattttaaa tctgtaaatt ctctttaaaa
    17821 tcttaggtgt atatcctgta tattttaaac agattctttc caatgtttta atatttatat
    17881 ttgtatcatc acaaaatgct tttatattgc tatatctatt aacatatata aatgaattta
    17941 gaagctttac atatttattt gaaattaaat cttcttctaa tatggataat aatacttctt
    18001 ctaaatataa aacaattttt tctactgatt gtattggatt taatgactct tccaattttt
    18061 ttgcaaatag ctgtgatact gcttctaggt caacaatttg tctgttaaac tctgaaattg
    18121 gtatctttaa aaatggatag agaccaaatg gataaaaaga aatccctata acacgtatat
    18181 ttccatgttg aataataaat ccatgtttat cccttattcc attaaaatgc atattactag
    18241 cagtatagtc ttgattttca attttatatt ccataacatc agaaagattg agaataatat
    18301 ctatactgtc tgtcggaagt aacttattat ttaacagtat atttgatttt gtctcaaaat
    18361 accaaataaa ctttacccac ggctttaaac ggacattttt gattgaatat cttgtaactg
    18421 ataacattgt gaactaacct ctatactaaa attttttaat tatgtactcc atcctaatat
    18481 tatacagtat aatttatgct atcataaagt ttagttcact ttatatttat tttatacatt
    18541 ttttcaatac cttagaaata ggaagcgcta ttataaggcc tatcaatact tgcattaaat
    18601 tacctggtat tgaagtaaga ggtactataa aattaccata aagtataact tctgttacat
    18661 aatatccaaa tagcatccaa attgatgaaa cacatattcc tattacattg attaaaaaat
    18721 tattcccatt attaccattt gcccatgcaa tctttccaag taaataaccc ataactcctc
    18781 taactataaa ggtaaacggt gcccataaag tccacccaga tatcaaatca aaaagtgaca
    18841 taccaatagc tcctgataaa gcaccttttt tacttccaaa tactattgct gatatgaaca
    18901 acattgcagt tcctaaatgc acaagcccac catttataga tattggtaat cttatgttta
    18961 taaatttagt tgcaataaat actaatgcta ttaatagtga ggtttccacc atgtctttcg
    19021 ttgtaaattt ttgcttagct gtaacttcca tactatatcc ccctatctat taaaaataat
    19081 acttattaaa taaatttaac aaatttccat ttcctttgaa tcctagtgca cttaaacttt
    19141 tatccaaaac atttagtaca tgttctattt tatttagatt tgcattctct cccatatgac
    19201 ctattcttaa aatagtatcc atatattgat ttagtgatgt tgcaacaagt gtattataat
    19261 ttttaagcat ataatcagta agttctaaag ctcctatact ttcaggaact tttatagctg
    19321 tgactgtatt agaatatcct tcttctaaaa atagttctag accatattcc tcaatagatt
    19381 ttctaacact ataagctatc ttttcatgtc tatttaatac attttctatt ccttcttcta
    19441 atatattatc aagtgcttta tcaagcccca ttatgtcact tattggcatt gtataaggga
    19501 agtatttttt ttcataatag ccttcccata tatttaaatt acaataaaaa cctattacat
    19561 cagtttttct attttttata caattttttg catcttgact tattccgact atagtaagtc
    19621 ctgctggtgc agaaatagct ttttgtgaac cacctaatat tatatctatt ttagattcat
    19681 ctacacttaa tctttctcct accatacctg ctacagaatc aactacagtt aatattccat
    19741 attctttaag taatggacat attttgctta catcatttaa tacgccagtt ggagtatcac
    19801 aatgcactac tgttgcatat ttaaaattac tatcctcatc taaaaatgct ttcaattcat
    19861 caatatctat acttttagta tattcacttg aaaaaagcac atactcccca ccatacattg
    19921 ttacaaaatc tttaaaacct tctccatata taccattgtc aattacaagt actctatctc
    19981 ctttttctgt aagtgatgca catgctgctt caagacctaa tattccttca ccactcaata
    20041 tgtaaacatc gttttttgtt ccaattatat taccaaactt ctcgcatgtc tttttataaa
    20101 attcaacaaa atcaatatct atatctggat ttgttgtttt ttctgctctt gctaatctta
    20161 cattttccct agtttcagtt ggtcctggtg cataattaat cttcttattc atatatatca
    20221 gctcctattt attttctata cgattattat acaaaatttt cattttatat ggtacaattt
    20281 tatacttttt tagaattgta ccggtacatt ttctaacatg aataatatca gtatattaga
    20341 tatattattg attacataat aaaatacaga gcaaacatct gcttaaattg tttgctctgt
    20401 actatgcttt aacctattta attatgaatc tctttaacta tattttttta tatgtttttt
    20461 gctagttaaa ctaaccataa atatttgtat tttattcact gtatcttact ctatcaataa
    20521 gagattcttt attaaaactt cgtcctatca aataagttgt tataaattga gctataagaa
    20581 tacacacaat catcaacaag attggtacta ttggcaaaga atatgttgca taagataatc
    20641 cagtcttttt tagaaatata acagcaatat accctaatat acctccaaat agaatacttc
    20701 ctatcatcat tccagaagtg taatacattg cctctgaatt aagcattttc actaattgtt
    20761 tattagtaag accaatagct tgaagcatac caagttcttt ttttctagta actatgctag
    20821 ttatcattgt gttgacaaga ttcataaatc caatcacacc tattatgcct gttagcgtgt
    20881 atcccattat ctttataaat gaaatagtag ccttatttga ctcaattcta ctatctataa
    20941 aatcagtctc taaaaatcca ttatttttag caatcttctt gatactatct ttgatttctt
    21001 gatactttcc ttcttctgta tatattccca agctactagt tgaatcgtat ttcaaagttc
    21061 tatcaataaa atccttccct ataccaaaac ttggaacccc catagctatt gcttgaactt
    21121 taaattcttt ttttatcttt ttatctccat catataaagt taatcttatt ttatctcctg
    21181 cttttactcc catttctttt gctgtatcaa catgagtaat tactatttca tctccagttt
    21241 gaagtctttc aagatttatt tttccatcta ttatattctt gtttaatgat tttacatcat
    21301 tttcatttat actttgtaaa aggtcatact taaattcaac atcatagtcc tccataccaa
    21361 tttttacact tcttgcagat tctattcttt taattccttc catgttcttt atttgattaa
    21421 aaaaatcttt acttagagga ttatccattt gtaaaatatt caaattatct ttaggatttt
    21481 tatcactgtt catttcataa ccagatagtc taacttctat atcataagga aagtgttctc
    21541 ttgccatttt ctcagcatca aaactttcta aagcagttga tactgttata aatatagttc
    21601 cactaagtat aagtgatgcc aatgtcatgt aagtacgttt tttatttctt tctaaattgg
    21661 catgtgataa tctctttaga tttatatttt tatatccttt tctcttactc ttattactta
    21721 ttttatttcc tgtatatctt actgcgtcaa caatggatac ttttgatgct actttcattg
    21781 gttttaaaag tgataaaaca acagatataa agcttattac cacaaccgat aatataactg
    21841 gtaatcgtga tgattttaca tctatatcca taaatgattt tattataata tttgcaagta
    21901 catagcctaa aattattcct attggtattg ctattccggc taatatgaac ccttctttaa
    21961 acactatatt ttttatttgt ttcttagttg caccaattgc tctaagtttt ccaaattctt
    22021 gaacctttgt aactattgaa atataaaata tattgtatat tactaaaata ctagataata
    22081 caattactaa ccctacaaaa actccaccca taatcgtttc catatctggt tttaaagcat
    22141 ttatataatt ttcatttaca gcagtattaa tagtatccag tcctatatca ttagcaattt
    22201 tatctaattt ttcttttgct tgctctattg ataaattact tttatcatta aatttcacat
    22261 aaatattaaa atcttcttgt gacatatctc tagtatttct catatatgat tctgatataa
    22321 tagcataata atatttacct gcttcagata tttcgctagt ttttaagatt ccacttataa
    22381 tgaactcttt ttcaattttt ttatcacttt tatagtcatc ataagatatt tttatctttt
    22441 cacctaaatc tttattttta taaccaagtg cctttaaagc tccactatct aacacaattt
    22501 cattctcttt tgatggcaat tttcctttga taaattcaaa actatttaat ttcaaagcat
    22561 cttcattcat gtatgctaga gaaatatttg aatcatcttc cagtttttca acacctactc
    22621 cattcatttc accagttaat tcaacatctg catgattact caatatatca gcctgttttt
    22681 catctacatt tgctaatata ccttgataat tacctgaata ctttatagta ttttcttttt
    22741 gatatgctcc tgcatcaaca atataaattc caatagaaga aagcattaag gttgaaagta
    22801 ttatagtaat tattattaga atactttttg atttattttg ctttaaatta ctttttgcta
    22861 ttttagtagt attaatcatt tttatcacca acctttaaca ccctgccatc ttctatgaat
    22921 ataactctat cagccatttg ggctatactg tcatcatgag ttatcataac tagagtttga
    22981 ctgtacttct tagacataga ttttaatata ctcataacct catcagatgt tttagaatct
    23041 aggtttccag ttggttcatc agcaagtatt atagctggtc ttgtagctaa tgctcttgct
    23101 attgccaccc tttgttgttg accacctgat aatgtatttg gtaaaacgtc gtgtttattt
    23161 tcaagtccta atgattttaa aagctctttt ataaaaggtt catctacctc tctaccatct
    23221 aaaccgattg gcaacattac attttcccat acattaagag atggaattaa attatagctt
    23281 tgaaatataa accctatttt tcttcttcta aatacagcaa gttcttcttc ttttaatgta
    23341 aatatatttt tattatctat atacaccttc ccagatgtag gtatatcaag acctccaatc
    23401 atatgcaaaa gtgtactttt tccagaacct gattttccta ttattgcaac aaattcacct
    23461 tcatttattt ctaaatcaac attgtccaaa gctcttacta agctttctcc ttttccataa
    23521 tgctttgata aattttcagt atatagtatt ttcataaaat tatcctctca ttctaagtta
    23581 tattactcca tattttatta attttttatt tctggagctg tttatactta tataataaat
    23641 gtagaggctt acattttcct ttcatttaat attacatagt tgtaagaaac aaagaaaact
    23701 tgctccctat tcctactttt gaagaaacta taatatttcc accttgttct tctaaaatct
    23761 ttctacttaa atacaatcct accccactac cttctacaga ttcaatttca tcagcagaac
    23821 ctctataaaa acgtttaaat atattattaa actcattttt ttcaatccct atgccattat
    23881 cctctattat aattttaaag aaattagcag tttcttctac agatatattt atttctccat
    23941 ttacctgtgt atactttaca gcattgtcta atacattaaa aatactctcc tcagtccact
    24001 ttttatcatg tggtataatt ctactgttaa attcatttaa atttaatgtt atacttttgc
    24061 tcttagcctt aggggtaaca ctttttactg catttagaat agtatttttt atatcattat
    24121 cttctttttt tatgtttatc atgctaattt ctaaccttga tatgttcact aaagaattta
    24181 ttaaattttc taatttattt atagaagcct tattggtcaa taagaactcg ttggcttcat
    24241 cttcttctaa ttcttcttct ataagtaatg tattgtataa ttttaaggat gctaaaggag
    24301 tttttaattg atgggaaata tctgttacta atgattttac actttctttt tctttttcta
    24361 atttaataaa ctttatcttt aaacttctat taagctcata tagacagtta tttatcttac
    24421 taaatatgcc ttctttaaag tattcattat attctactag ataaccagtt tcttctgact
    24481 cagtagtgtc cttcaagtag ttttcttgtg acatcttatc tactataaaa taaattttac
    24541 tcaatctttt atttatgtat cttataaaat aatatattat acctataact actataaaca
    24601 tcattaaaaa aataaaaaat gattccttaa aaaaagattt taagtataag ctaaaatttt
    24661 tatcatttga cattttattt tccaatccat agccaaattt cttaaatgcc ttttctccag
    24721 tagacacctt actataatca gaattataaa tagaatttac tatatctatt tcatcattag
    24781 gatatttttc aatcaatatt ccagcaatat tttgagtatt ttttatttga tgttcataca
    24841 atttatgtaa tctgctatat tcaaaaagta taaatacaag ggttactatt agtacagata
    24901 aaacagaata tacaataact cttctcatta tataatcatc tttcacactt aaaccatctt
    24961 tgaggttcat attttttagc atttttttat actcctttct ccccacatat atccaacccc
    25021 tcttactgtt tttatatatt taggttcaga tggatttttt tcaacctttt gtctaagtct
    25081 tcttatattt actgcaatcg tattatcatc tacaaaatta ccactactat cccataaaga
    25141 ttctaacagt tgctctttag tcaatgtctg catagaattt tccatcaaat attttaatag
    25201 ttttgtctct gtcttactta aaattatctc ttcttcctta tcatctgttc ttataattaa
    25261 tttattttct atataataaa agaataaatc atcacaaact aatagagtat aattttttac
    25321 tgtatttact cttttcataa gcgcattcac ttttgatatt aataccatca agctaaaagg
    25381 ctttgtgata taatcatctg cacctaaatc atatcctgtg acaatatcca cctcttcatc
    25441 aagagctgtc aacattatta tgtaaacatc acttttcttt ctaatctcct cacaaaagtc
    25501 aaaaccacta ccatcaggta gacctatatc ggaaataatt aagcatatct cttcttttgc
    25561 gaaaatattt tttgcttctt ctataccaaa tgcactaaaa acattgtatc cttctttttt
    25621 taatttaaaa ctaattcctc tatttaaaga tttgtcatct tccaaaagta atatattatt
    25681 catccctata tcctccatta tcatatatac tagctaaatt atatcatact aataaaatca
    25741 tttttttatc aatttgtaaa tatatcagaa gttgttaata tgatttcatt tacttgaata
    25801 aaaactaaaa atccccataa tactatgcca tttagtgtaa ttatttttca taaaatacaa
    25861 ttttatttaa aagtaatcat gttaaaacat aaaacaaagg aaattagtat ttatataact
    25921 aatttccttt gctgtttact attatctaaa attaaattac tatctactag tttttgctca
    25981 ttaattttta ttttgacttt ttatccttta actctttttg attaaaattc aataaacata
    26041 tcaatgtact tgaaactata aatataatta tactatttga aaaacctaaa tctcctgttt
    26101 taggagattt ttctttagct tctcttttag atattcctag attagaactt tctctagaac
    26161 ttgttttatc taagctttta tttttatcac tatcagagct ttttatatta ttagatagat
    26221 tctcttcatt atcattgata tttttttcat tttcacttaa tatcaaatca ctctcatgat
    26281 tcttgcttat taactcatct ttagatttaa taccaattct tccatctaca ttttttgata
    26341 tttctttttt gtactctata tattcaatga ctgcactctc taaatttcca aattccttta
    26401 gtattggctc ttttgaaaaa caaggaaatt catctccacc tgaggctata taatcattcg
    26461 ttgcaactac atacttttta tttaaatcta atggctttcc ttctttttga atatttgtta
    26521 ttttttcgcc ttctttttgt ttaggattaa agtaatatga aattcctccc acttgcaaaa
    26581 aggctgaact tttttctggg taaagtttta ctccatgctc caatacatct ttaatctgtg
    26641 ctcctgtaag ttctttggta actatagtat tgttaaaagg aaatacatct acaatatctc
    26701 ttcttgttat attgcctttt tctatcgtat ctcgaatatt ccctccatta aataaagaaa
    26761 tatcagcctt agttttatct agtaaaatgt cacttattaa attacccaaa ttagtttctt
    26821 ttgtccttac attttcatat gaaccatcta gagtatttgt agttacccct ataactttat
    26881 ctaatatttt ttcttgttgt tcttttattt catcaacctt tttacttaca gcggagtcaa
    26941 gcttatactt taatgcttct tcttttccaa ttaatctagc tgatttattt tctattttta
    27001 tatcttctac atcattagta tccaaagtta gttttatctc gccaatattt tctaaatatt
    27061 gtcctgcact tacaatcaat gtatcaccca cttgtttacc attttcaaac ttagtgtggc
    27121 tgtgtccatc aataatcaaa tcaattcctt gaacctcatt tgctatatct atactatttg
    27181 gcttacttaa actatttgta ccaatatgac atattgcaac tattacattg gcaccttttc
    27241 cttttaattc atttacttgt tctgttgcac tttctatagg atttttaaac tctaatcctt
    27301 ccacattttt aaatccagtt ttgctctttg tttcctgggt tgagagtcca aaaaatccta
    27361 tttttattcc atctatttct tttatatcat tactatcaaa aacttttttt ccattttcaa
    27421 aaatatttga tgataaaaat tttaaagtat tctctcctaa attagcactt ttagataact
    27481 caaacagtct atcttttcca taattaaagt catgatttcc aggagtaata tagtcatatc
    27541 cagcacattt aattaattca attgcacttt tccctctatc catatttact attggaagtc
    27601 catgcaaaca atctcctgca tctactaaaa ttgagtttgg agtttctttt ttcaatgtgg
    27661 ctagatttcc tatttgtata tggtcatcac cttcagcata tcttccatgt atatcattag
    27721 tgtgaaaaat ggttatttct tcaaatcgct ctagcccata agaaataaaa ctctgacttg
    27781 ttgtaattag aattataatt accaaaatta aataccttct aatcttcaat ataaattagc
    27841 ctcctcaaat tagttttagc tttaatataa aatttatatt ttacataaaa ctttttagat
    27901 aaatattaaa ctatagtaag attaattagt gtaattttta atatttatct atcaatttaa
    27961 ttttgtccat atccaattag ttttaatcta at
//
LOCUS       DAEPUT010000050        27950 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.052, whole genome shotgun sequence.
ACCESSION   DAEPUT010000050 DAEPUT010000000
VERSION     DAEPUT010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27950
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.052"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            35..196
                     /locus_tag="KRL22_002333"
     CDS             35..196
                     /locus_tag="KRL22_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272817.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALIAVGLVFNAGGVKDVLL
                     ELFNRIIGA"
     gene            273..509
                     /locus_tag="KRL22_002334"
     CDS             273..509
                     /locus_tag="KRL22_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272818.1"
                     /translation="MKDIFTDMQAKIGCPYLSDLPYYKRAVWFEIKRLCLSDYPKKQL
                     EDFSRYVFGVPYTVIQEALQRKDVMKHGRNACAD"
     gene            484..981
                     /locus_tag="KRL22_002335"
     CDS             484..981
                     /locus_tag="KRL22_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1272819.1"
                     /translation="MEEMRVQIEAREPTDGEIRVFWFTLPIDTEQVEELLGIDIDTDY
                     YYITGKELPFADEVQEDTTIEKLDDLYHTYESLPSDLKEDYGELMCYFTDLDELHRYR
                     NDIIHYSWCKNMTDVARHILNNDPDFTSLSENVTRYFDYEAYGQYLDDNGRFVETDHG
                     IYELP"
     gene            999..1502
                     /locus_tag="KRL22_002336"
     CDS             999..1502
                     /locus_tag="KRL22_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1272820.1"
                     /translation="MVDDMRVYIANLGKYNEGELVGDWFSFPIDEEDVAERIGLNSYY
                     EEYAVHDTDNFPIEIGEYISIEELNEMYDMICELPDYITDALDEFVSYYGSLEEVYEY
                     KDEIYYYPNCEDMTDVAYYFIDELQVLGQIPLPLQNYIDYEAYGRDLSIEGTFIETSR
                     GICEIPY"
     gene            1612..2001
                     /locus_tag="KRL22_002337"
     CDS             1612..2001
                     /locus_tag="KRL22_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1272821.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFTLPFPVTFTQITWFVITEFAV
                     ILLGDLPPLSLIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITFALRPKVTY
                     AGKAVKLEKEVFSEPVTAVRSVMYVPD"
     gene            1988..4435
                     /locus_tag="KRL22_002338"
     CDS             1988..4435
                     /locus_tag="KRL22_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1272822.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSVRSIQEQSKKLVTGRLRDVAIQKIDEQTEALVSMI
                     GDNQVDYRFFIGFKLIVTEEKVSLDSMKKSAFMTFKEFLHEVNHTLMNDFISMPDDEI
                     NRYMKMEKLLENKISRRFKFRRLDKNDFGYLIEHIYGRDGVAYEDYEYSLSKKKLRKA
                     TLIKQYDLIRPTRCLIEESQRYLRLEHEDSESFVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVGNRKALSTVRNKKKELKDLDNHAYQSGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYIGYSVDTGRNVYLQPS
                     LASQGIKGTVTNALASAFVGSLGGGKSFCNNLIVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKENAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRAVTQSDQRGLLHVIDELRREDTAIARNIADHIDSFTDYDFAHLLFSDGSV
                     SNAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVAMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVKSEVE"
     gene            4435..6567
                     /locus_tag="KRL22_002339"
     CDS             4435..6567
                     /locus_tag="KRL22_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1272823.1"
                     /translation="MKDKIKGLLTRKKLFRFFKIAVIVVLTTIALLSLLGTVAHASGL
                     VDDTVNADNLYSQYPLENYQLDFYVDNSWGWLPWNWLDGIGKSVQYGLYCITNFIWTI
                     SLYLSNATGYVVQQAYKLDFINDMADSIGKSIQTLAGVTENGFGSTGFYVGFLLLIIL
                     IVGIYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINDFSSDISTAS
                     LDLGTKIMLPDSDSAGKDSVDLIRDSLFSIQVQQPWLLLQFGNSDIEEIGADRVEALV
                     SASPSAGDGATREDVVKTEIEDNDNDNLTIPQVINRLGMVFFLLIFNLGITIFVFLLT
                     GMMIFSQILFIIFAMFLPISFLLSMIPSYENMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMIAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YMFMRHRARRMEHRIARAVGAGSVAGAVAGTVAGTTMNDGSGKSARAGTGRKERRENA
                     SFGSRAGSTVGAVLDTKNKVKDKATAVKENIKDMPTQTAYALHSAKEKAKENVSDFKR
                     GIVQGQETRQSQRADKREQHRQNIADKRMELQKAQEARQTGRTTDGSATTGATRPHDR
                     PVTASKTDTGKVQEIKRPVTTDKVHTEPTKAQPVKERPLASKSAEPVLQKHGTRLNGV
                     ELNQQTTRKERNIKKATLNMTGKKGRKK"
     gene            6564..7151
                     /locus_tag="KRL22_002340"
                     /pseudo
     CDS             6564..7151
                     /locus_tag="KRL22_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            7865..9730
                     /gene="ltrA"
                     /locus_tag="KRL22_002341"
     CDS             7865..9730
                     /gene="ltrA"
                     /locus_tag="KRL22_002341"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016283884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBH1272824.1"
                     /translation="MNRVKTSKTLRHSEYYDMTETFDRLYEASQNQQIFVDIMSVIMS
                     DENIMLAYRNIKKNKGSNTKGTDKQTIQNIELMSEKEFVQKIKDMFCCYTPKPVKRVN
                     IPKPNGKLRPLGIPTIWDRIIQQCVLQVLEPICEAKFHNNSYGFRPNRSAHHAIAQCY
                     RLMNQSKLQYVVDIDIKSFFDNVNHAKLIRQMWTMGIRDKHLLGIIRAMLHAPIILTD
                     GKIEHPKKGTPQGGILSPLLSNIVLNELDWWIASQWEEIPTKSKSARVLDRRDKGKGI
                     DKGNKYKELRKSTLKEIYIVRYADDFKIFCRKRKDADKIFHAVIQWLEQRLSLDISEE
                     KSKIVNLRKQKSEFLGFEMKLVRKADKYVVQSHMSKKAMNKAENNLKEQIKRIQHPAN
                     DREQAKEISIYNSMVVGIHNYYNKATLIAFDCSKVNYIISNWIDNRLNVTKQGAIQNK
                     YLSKKYGKSQQIRWLNNCPIIPIGYVKHSKAISIKNEICKFTPKGRELIHKSLDIDVG
                     VLVQLMKNPILDMSVEYNDNRISKYTAQLGRCAVLGVSLSFQEIHCHHIKPISDGGTD
                     KFQNLIIVHESIHKLIHATSQEIISKITNKFKLNKKQISKINALRIKVNNGVITV"
     gene            9825..10160
                     /locus_tag="KRL22_002342"
                     /pseudo
     CDS             9825..10160
                     /locus_tag="KRL22_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896986.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
     gene            10816..12612
                     /locus_tag="KRL22_002343"
     CDS             10816..12612
                     /locus_tag="KRL22_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBH1272825.1"
                     /translation="MKQTMEILTKLQENSKKNHDEVFTRLYRYLLRPDIYYVAYQHLY
                     SNKGAGTKGVTDDTADGFSEIYIENIIEALKNEMYQPKPVRRTYIKKSNGKMRPLGLP
                     VFTDKLIQEAIRMILEAIYEPIFSDYSHGFRPVRSCHTALAQIKKEFTGARWFIEGDI
                     KGCFDNINHAVLVEIVNQKIKDARFLKLIRLFLKAGYMEDWKYHETYSGCPQGGIISP
                     ILANIYLNELDRHIMKIKKEFDVATKARYTPEYTKLVGLRQRLHNKIKNSNGIEREKL
                     IEEYKTATAQMLKLPAKQCDDKKIKYVRYADDFLIAVNGNRQDCEKIKQELTEFISTT
                     LKMELSQEKTLITHSNTPARFLGYDVRVRRDQQIKPKGKFKTRSMNNKVELSIPFKDK
                     IEKFLFSNGIVKQRSDNGKLEPIHRPQLLNRTDLEIVTIYNAELRGICNYYGLASNFN
                     KLIYFNYLMEYSCLKTLAGKHRSKVSKIRAMYKDGTGKWAIPYETKTGIKKMYFANYA
                     DCKGKKFTDIVPQTAKNYSHDVTTLESRLKAKICEVCGCTDSDRYEIHHVNKVKNLKG
                     KSEWEKVMIAKRRKTIVVCHKCHMAIHHGEKK"
     gene            12730..12837
                     /locus_tag="KRL22_002344"
                     /pseudo
     CDS             12730..12837
                     /locus_tag="KRL22_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989669.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
     gene            12862..13755
                     /locus_tag="KRL22_002345"
     CDS             12862..13755
                     /locus_tag="KRL22_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1272826.1"
                     /translation="MFKKKENPIKEKKIRTMKVGTHKKSVIALWVVLIASVSFGVYKN
                     FTAIDQHTTHEVETIQLRLNDTNGIENFVKNFCKSYYTWSNSKEAIEARTQAINAYLT
                     QELQDLNVDTVRTDIPTSSTVTDVLIWDVEQSGENAFSVTYEVDQQIKEGDQTRNVSE
                     TYTVTVHVDADGDMVIIQNPTLAPAMEKSSYEPKAQEADNSVDADTVNDATAFLETFF
                     KLYPTATDKELAYYVEGNALEPINGDYLYSELVNPVFTADGENVRVSVAVKFIDNQTK
                     ATQVSQYELTLHKDSNWKIIG"
     gene            13867..14478
                     /locus_tag="KRL22_002346"
     CDS             13867..14478
                     /locus_tag="KRL22_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015555122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1272827.1"
                     /translation="MNQNKENSKKTFDKQAISYDTDMVGEHARNLYAPILKILKQEHH
                     VGSLLDLGCGTGALLESIFNLNITRQLSGIDLSPNMIEEAKKKIGDNVKLYIGDAEKL
                     PFEDGLFDTVICNDSFHHYPAPNRVIKEVSRVLKKGGLFVIGDCWQPAGARQIMNFYM
                     KHSKSGDVKIYSKKEMENLLSKDFCTVLWERISNTSSLTIARK"
     gene            14542..15102
                     /locus_tag="KRL22_002347"
     CDS             14542..15102
                     /locus_tag="KRL22_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1272828.1"
                     /translation="MRISKEPEERKQEILETAMKLFAQNGFEKTSISDIAKEIGVAQG
                     LCYRYFPSKDVLFQTALNEYANILVSKMTKNINIKQDTLKEILNKMTLFSEHESDLYY
                     QVFHDKQNKNFHDLLVLCVCKKLTPIVQDIIIRANQNHEINISDPETCASFCVFGQLG
                     ILMNNEIAFSEKSDRIKTFFNNLFNF"
     gene            15179..16495
                     /locus_tag="KRL22_002348"
     CDS             15179..16495
                     /locus_tag="KRL22_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1272829.1"
                     /translation="MNSKIDFINGNTKKCLLSMTLPMIVAMFLNMAYNLVDSLWIGNL
                     LGEQAYAALTNSTPIILILTSIGMGATNGVSILLSQAIGAKEETKKKRVLSTSFFVSV
                     IFSILITILLEVFLNPILTALNTPDEIFDMARSYLSIYILGYVAVYLYLYFTAILRSF
                     GNTMFQAVAMLVSTLLNAILDPILIKIIGFHGAAIATLTSQIICLIFMCIYISKKKLF
                     KFTLSDFDKLEIMPLIKNAVPSVIQQSIPAISTTFLTALVSGYGISAIAGYGVTGKLE
                     TILFYPAMALNMVLTSIVGQCIGGKRIDRAKDYLKLSLKYGSITLIILSLIIIVFSKQ
                     LAGLFVASENVAVIVNQYFTIVSIGYVLYTITSCCLGTLNGLGKPTRSMILMIFYYIV
                     IRIPLAYIFANLGSGLVGIWLAILISHIVACIASIICGIGSMKIKE"
     gene            16500..16724
                     /locus_tag="KRL22_002349"
     CDS             16500..16724
                     /locus_tag="KRL22_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272830.1"
                     /translation="MIGLKRYDMKALLKAGAKARGLSLPEFRAEIQKNIDNAMNSQDP
                     VVQKHFKKYFGNKIPTPEEYIYTITKKTKI"
     gene            complement(16794..17156)
                     /locus_tag="KRL22_002350"
     CDS             complement(16794..17156)
                     /locus_tag="KRL22_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272831.1"
                     /translation="MRKKKDTHSFDFRPLGLAIREAREKAGLSRNDLGDKVFYGERHI
                     ADIENIGKHPSFQLFHDLVTMFHISVDEYFYPQEKAEKSTIRRQIDVSLDELTDEELK
                     IIQGTIDGIMKYKGTGSK"
     gene            17683..18105
                     /locus_tag="KRL22_002351"
     CDS             17683..18105
                     /locus_tag="KRL22_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1272832.1"
                     /translation="MKPSDFQKTIQCQFDCKLKRTVKGVIWNYKKELKRRKDKEIPFC
                     ELPEIVVEKLAVWDEYMSDYTVFEVCGVEIRVLDEELSEALKQLSERNRENLLMYYFL
                     EMSDTEIAKAQKISRAGVFKNRYRALQNLKKTLTKERE"
     gene            18109..18357
                     /locus_tag="KRL22_002352"
     CDS             18109..18357
                     /locus_tag="KRL22_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009264382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1272833.1"
                     /translation="MKKGYKLPPYRLISSAVDGNEQSIERILAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGRIREAIIKMILGFDIGTVPIEE"
     gene            18728..18931
                     /locus_tag="KRL22_002353"
     CDS             18728..18931
                     /locus_tag="KRL22_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1272834.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGENKLRRLAEENIGSNWVI
                     MNGNRMQIKRKQFEKILDKLDAI"
     gene            19010..20206
                     /locus_tag="KRL22_002354"
     CDS             19010..20206
                     /locus_tag="KRL22_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1272835.1"
                     /translation="MAKEVRRDNKGRILRTGESQRADGRYLYKCTNALGESVSLYSWK
                     LVPTDKIPKGKRKDISLREKIEQLQKDLNDGIDPAGKKITVCQLYDKKNSLRKNVKHN
                     TVKGRKQFMNLLKKDPLGSMTIDTVKLSDAKEWAIRMSENGVAYSSIRNYKRSLKASF
                     YLAIQDDYIRKNPFDFKLSDVLDDDTEEKVVLTPEQEASLLSFMQSDKTYRKYYDEVV
                     ILLETGLRISEFCGLDLNVAVDMRNRSILVEHQLLKDKEIGYYISTPKTKNGSRQVPM
                     SKKAYEAFKRVIKNREKGISFTVDGYSRFLFLNQKGLPKVAGNYDGMLRGLVKKYNKT
                     HDEPLPHITPHTFRHTFCTNMANKGMNPNTLQYIMGHANITMTLNYYAHGSYASARSE
                     MDRLCA"
     gene            complement(20446..21111)
                     /locus_tag="KRL22_002355"
     CDS             complement(20446..21111)
                     /locus_tag="KRL22_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HBH1272836.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            complement(21111..21767)
                     /locus_tag="KRL22_002356"
     CDS             complement(21111..21767)
                     /locus_tag="KRL22_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HBH1272837.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            complement(21776..22954)
                     /locus_tag="KRL22_002357"
     CDS             complement(21776..22954)
                     /locus_tag="KRL22_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH1272838.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            23309..24211
                     /locus_tag="KRL22_002358"
     CDS             23309..24211
                     /locus_tag="KRL22_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1272839.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            complement(24427..25239)
                     /locus_tag="KRL22_002359"
     CDS             complement(24427..25239)
                     /locus_tag="KRL22_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272840.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(25242..26201)
                     /locus_tag="KRL22_002360"
     CDS             complement(25242..26201)
                     /locus_tag="KRL22_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272841.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            complement(26307..27866)
                     /locus_tag="KRL22_002361"
     CDS             complement(26307..27866)
                     /locus_tag="KRL22_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1272842.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSNGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
BASE COUNT         9152 a         5119 c         5603 g         8076 t
ORIGIN      
        1 ctggttttta agcaacgccc agagcttggt gcttatggca atcgtggtaa tcggtatcta
       61 cttaggattt aagagagagt tttcaaaact tatcggcttc ttggtagttg ccttaatcgc
      121 cgtcgggctg gtattcaatg caggcggtgt caaggacgtg ctgttagagc tgttcaaccg
      181 tatcattgga gcgtagccta tcgttaaaag cggttactcc attggagatc aaccactttt
      241 tctatactca aatttcagat tggagtgatt gattgaaaga tatttttaca gatatgcagg
      301 caaaaatcgg ctgtccgtat ctctccgacc tgccctacta caagcgtgcg gtctggtttg
      361 agataaaacg cctttgcctg tctgactatc caaagaaaca gttggaagat ttttcacgct
      421 atgtattcgg tgtgccttac accgtcatac aggaagcgtt acaaagaaag gacgtgatga
      481 aacatggaag aaatgcgtgt gcagattgaa gcaagagaac cgacagacgg agaaatccga
      541 gtcttttggt tcaccctgcc tatcgacaca gaacaggtag aagaactgct ggggattgat
      601 atagatacgg actattacta tatcacggga aaggagcttc cctttgctga tgaagtgcag
      661 gaagatacca ccattgaaaa actcgacgac ctgtaccata cctatgaaag tctaccctct
      721 gacttgaaag aggactacgg ggagctgatg tgctatttca ccgaccttga cgaactgcac
      781 cgatacagaa acgacatcat tcattattcg tggtgtaaga acatgacgga cgttgcccgc
      841 cacattctga acaatgaccc agactttact tcccttagtg agaacgtcac ccgctatttc
      901 gattatgaag cctacgggca gtatcttgac gacaacggac gctttgtgga aaccgaccac
      961 ggtatctatg aacttccata gaaaagaggt gtaagcctgt ggtggacgac atgagggtgt
     1021 atatcgctaa tcttggcaag tacaacgagg gcgagcttgt cggggactgg ttttctttcc
     1081 ctatcgacga ggaagatgtt gcggagcgta tcgggctgaa cagctattat gaggaatacg
     1141 ctgtccatga taccgacaac ttccctattg aaatcgggga gtatatctcc attgaagaac
     1201 tcaatgaaat gtacgacatg atttgtgagc ttcccgacta tatcacggac gctctggacg
     1261 agtttgtttc ctactatgga agtctggaag aagtttacga gtataaggac gagatttatt
     1321 attatcctaa ttgcgaggat atgaccgacg ttgcctatta cttcattgac gagttacaag
     1381 tgctgggaca gataccgcta ccgttgcaga actatatcga ctatgaagca tacggcaggg
     1441 acttgtccat agaggggacg ttcattgaaa caagccgtgg gatatgcgag ataccatatt
     1501 agagctggca gatcagcgac aggaagcgtc gctactgaca gcttttttct atcaaggaca
     1561 gtctgaaaaa tggctgtcct tttccattac aacgaaagga gctgaaacga attgaagaag
     1621 attaagagct acacaggtat ctggaacgtg gaaaaagtgc tgtacgcaat caatgacttt
     1681 actctcccgt ttcccgttac ctttacccag ataacgtggt ttgtcattac ggagtttgcc
     1741 gtcattctct taggggactt accgccgtta tcgcttatcg agggggcatt tttaaaatac
     1801 ttcggtattc ccgtcgccct cacatggttt atgagccaaa agacctttga cggcaagaag
     1861 ccttacagct tcttgaaatc gcagattacg tttgccctgc gaccaaaagt gacctatgca
     1921 ggaaaagccg tgaagctgga aaaggaagtg ttcagcgaac ccgtcacggc ggttaggagt
     1981 gtgatgtatg ttcccgatta aatatatcga caacaacctt gtctggaaca aggacaatga
     2041 ggtattcgcc tactatgagc tgataccgta taactattct tttctgtcag cagagcagaa
     2101 atttatcgtc catgacagct tccgtcagct tatcgcacag agccgtgagg ggaagataca
     2161 cgccttgcag atagcgacgg aaagctccgt cagaagcata caggaacagt caaaaaagct
     2221 ggtgacgggg cgacttcgtg atgtggcgat acagaagata gacgaacaga cagaagcgtt
     2281 agtaagcatg attggggaca atcaagtgga ctaccgcttt tttatcggct tcaagctcat
     2341 tgtgacagag gaaaaggtca gccttgacag catgaagaaa tcggcgttta tgacgttcaa
     2401 agagttcttg catgaggtca accatacgct gatgaacgac tttatctcca tgccagatga
     2461 tgaaatcaac cgctacatga aaatggaaaa actgctggaa aataaaatct cccgccgttt
     2521 caagttccga cgcttggata agaacgactt cgggtatctt atcgagcata tctacggcag
     2581 ggacggcgtg gcgtatgagg actacgaata ttcgctttca aagaagaaac tgagaaaggc
     2641 aacgctcatc aagcagtatg accttatccg tccgacccgc tgtctgatag aggaaagcca
     2701 gcgatacttg cgtttggaac atgaggacag cgagagcttc gtgtcctact ttaccgtcaa
     2761 tgcgattgtg ggcgagctgg atttcccgtc gtcggaaatc ttctacttcc agcaacagca
     2821 gttcaccttt cccgtagaca cttccatgaa tgtggaaatc gtcggcaacc gcaaggcact
     2881 ttccacggtg agaaataaaa agaaagagct gaaagatttg gacaaccacg cctatcagtc
     2941 tgggagtgaa accagctcaa acgtggtgga cgcattagac agcgtggacg agctggaaac
     3001 cgacctcgac cagagcaagg aaagcatgta taagctctcc tatgtgataa gggtatcagc
     3061 tcccgacctc gacgagctga aacgacgctg tgatgaggtc aaggacttct acgacgattt
     3121 aaacgtcaag ctagtgcgac ctgctgggga tatgctgggg cttcactctg aatttctccc
     3181 cgccagcaag cgttacatca atgactatgt gcagtatgtg aaatcggact tcttggcggg
     3241 gcttggcttc ggggcgaccc agcagttagg agaaaacaca ggtatctata ttggctattc
     3301 tgtggacaca ggaagaaacg tctatttaca gccctctctt gcttcacagg gtatcaaggg
     3361 gacagtcacc aacgctctgg cttccgcttt tgtcggttcg ctgggcggtg gaaagtcgtt
     3421 ctgcaacaat ctgattgttt actattctgt cctgttcggc gggcaggcgg tcattctcga
     3481 ccctaaatca gagcgtggca actggaaaga aacactccca gagatagccc atgaaatcaa
     3541 tatcgtcaac cttaccagcg ataaggaaaa cgctgggctt cttgacccat tcgtgattat
     3601 gaagaatgta aaagacgctg aaagtctggc gatagatatt ctcacattcc ttacggggat
     3661 ttcctctagg gacggcgaga aattccctgt ccttagaaaa gcggtgcgag ccgtgaccca
     3721 gagcgatcag cgaggactgc tccatgtgat agacgagcta cgcagagagg acacggcgat
     3781 agcccgcaat attgccgacc atatcgacag ctttacggac tatgactttg cacatctgct
     3841 gttctcggac ggttcggtgt ctaacgctat cagcttggac aaccagctca atatcataca
     3901 ggtggcagat ttggtacttc ccgacaagga cacgaccttt gaggaataca cgaccataga
     3961 actgctgtcc gtggctatgc tgattgtcat tagtaccttt gcccttgatt ttatccacag
     4021 cgacaggagc atttttaaaa tcgtagattt agatgaagcg tgggctttcc tcaacgtggc
     4081 acagggcgaa accctctcaa acaagctggt gcgtgcggga cgtgctatgc aggcgggcgt
     4141 gtacttcgtc acgcaatcct ctggggacgt gtccaaagag agcctaaaga acaatatcgg
     4201 gctgaaattc gctttccgct ctacggacat caacgagata aagcagaccc ttgaattttt
     4261 cggtatcgac aaggacgacg agaacaacca gaaaaggctt cgtgatttgg agaacggaca
     4321 atgcctgctt caagacttgt acgggcgtgt gggcgtggtg cagatacacc ctgtctttga
     4381 agaacttctt cacgcctttg ataccagacc gcccgtaaaa agcgaggtgg agtgatgaaa
     4441 gataagataa aggggcttct gacaagaaag aagctctttc gttttttcaa gatagctgtg
     4501 attgtggtac tgacgaccat tgccctgctc tccctattgg ggacggtggc acacgcttct
     4561 gggctggtag atgatacggt caatgcggac aatctgtatt cgcagtaccc tttggagaat
     4621 taccagcttg acttctatgt ggacaatagc tggggctggc ttccgtggaa ctggctggac
     4681 ggtatcggaa agagcgtgca gtatggactt tactgtatca ccaactttat ctggactatc
     4741 agtctgtacc tttccaacgc cacggggtat gtcgtccagc aggcgtataa gctggacttc
     4801 atcaatgaca tggcagacag tatcggaaag agcatacaga ccctagcggg cgtgacggaa
     4861 aacggctttg gaagtacggg cttctatgtg ggcttcctgc ttctcattat ccttatcgtg
     4921 ggtatctatg ttgcctacac gggactgata aagagagaaa ccagcaaggc actccacgcc
     4981 gttatcaact tcgttgtggt gttcgtgctg tccgcttcct ttatcgccta cgctcccgac
     5041 tacatcaaga agataaacga tttttccagt gatataagta ccgcttcgct ggatttgggg
     5101 acaaagataa tgctccccga cagcgacagt gcggggaaag acagtgtgga cttgataagg
     5161 gacagcctgt tttccataca ggtacaacag ccgtggctac tcctgcaatt cggcaacagt
     5221 gatatagagg aaatcggggc tgaccgtgtg gaagctctgg tatcggctag tccctctgcc
     5281 ggcgacgggg cgacccgtga ggacgtggtg aaaacggaaa tcgaggataa cgacaacgac
     5341 aatctgacga taccgcaggt catcaaccgt ctgggaatgg tgttcttcct gctcatcttc
     5401 aatctgggga taacgatatt tgttttcctg ctcacaggca tgatgatatt ctcccagata
     5461 ctttttatca tcttcgctat gttcctgcct atcagctttc ttttaagcat gatacccagc
     5521 tatgagaaca tggcgaaaca ggcaatcgtg cgagtgttca atacgattat gacaagggcg
     5581 ggtattaccc ttattgtcac agtggctttt tctatttcca gtatgttcta caacatatct
     5641 accgattacc cgttctttat gattgcgttc ttgcagatag tatgtttcgc tggtatctac
     5701 atgaagctgg gcgaccttat gagtatgttc tctcttaatg ctggggacag ccagagcatg
     5761 ggacgcagga tattccgtcg cccgtacatg ttcatgcgac acagggctag gcgtatggaa
     5821 caccgtatcg caagggcggt tggtgctgga agtgtcgctg gtgcggtggc tggcacagtg
     5881 gcaggaacaa ccatgaatga cggttctgga aaatctgcca gagctggtac gggaagaaag
     5941 gaacgtcgag aaaatgcttc tttcggaagc cgagcgggtt caaccgtagg tgcggtactt
     6001 gatacgaaaa acaaggtcaa ggacaaggca acggctgtca aggagaacat caaggatatg
     6061 ccgacacaga ccgcctatgc cctgcactcc gctaaggaaa aggcaaagga aaatgtgtct
     6121 gacttcaagc gtggcattgt gcagggacag gaaaccagac agagccagcg tgccgataag
     6181 cgtgagcaac acagacagaa tatcgctgac aagcgtatgg agcttcaaaa ggcacaggaa
     6241 gcaaggcaga ctggaagaac gacggacgga tcagcgacaa caggagctac ccgtccccat
     6301 gacagacctg tcaccgcttc taagaccgac acaggaaaag tgcaggaaat caagcgtcct
     6361 gtcaccacgg acaaggtaca taccgagccg acaaaagcac agcctgtcaa ggagcgtccg
     6421 cttgcttcaa aatctgctga acctgtattg cagaaacacg gaacaaggct caatggtgtg
     6481 gagctgaacc agcagaccac cagaaaagag cgaaacatca agaaagcgac tctaaacatg
     6541 acaggaaaga aaggacgtaa gaaatgaaat taagacatat cgcccttatc ggcagtctgt
     6601 ttccctttct tcttgcgata gtgcttttct ttggtgtgct tatcagtgcc gaggacgacg
     6661 acgggggcgg tggttcttcc tcatgggtaa cgggaatgaa cctgtccgca gaggtattga
     6721 aacatcagcc tatggtagag aaatacgcta aagagtacgg catttccgag tacgtcccct
     6781 atctgctggc aatcatacag gtggaaagtg gcgggacagc cgaggatgtt atgcagagtt
     6841 ccgagagcat gggcttaccg cctaactccc ttgatacaga aagctcaatc aagcaggggt
     6901 gcaagtattt tgcgtccctg ctttcttcag cagaaagtca aggcatagag gatataaacg
     6961 tggtggtgca gtcctataac tatggcggtg gctatatcgg ctatgtggct tccaatggaa
     7021 aaaagcacag cttcacgctg gcagagaatt tcgcccgtga caagtctggc ggaaagaaag
     7081 tcacctatac gaaccctatt gctgtcgccc gcaatggtgg ctggcgttac gggtatggga
     7141 atatgttcta tggtgcgaca cgtttctgac tgaaaaggtc aggcacttaa atctgaaagc
     7201 gtaataatcg ttttccttta aggagaactg ataactcaaa gggtggaatg attgggtaac
     7261 gccttgaaac gccctctctg atactccgat tagcatttat tttatagcag ataagtgtta
     7321 aaagctcggt gaagtcggct gaaagttacc gtaaatatac aaaatggata tacgaaacct
     7381 gttcagaggt ggacggtgta actgataggt cgggagtcta taaactgttc acggtgagaa
     7441 tgaaattact gacgaacttg cgaatgaaag agtctataac atgacggtat agaaatgtat
     7501 cgggttctat aaaacggacg catatcgtgg ttgagtaaaa atcgtagata tgaaaaacca
     7561 tgcagtgtta caggcgttgg agatatgcag gcttaaagca agcacctaaa aacagatgta
     7621 aagatagagt tatcggaacg tggaaagctg acaacgggga gattgctata aatctatgaa
     7681 acggttgcta ggaatacata atagcattta tatcagtgaa agtagtggca cagtacctaa
     7741 gaagccatag aaatatggtg gagggatagc cacaagtcag tctttaaact taactatgct
     7801 atatacttca tagaatcgag taagacaaaa taaacaccaa atcctaatag aaaggactgg
     7861 tgctatgaat agggtaaaaa caagcaaaac acttcgtcat agtgaatatt acgatatgac
     7921 ggaaaccttt gaccgactat atgaagcaag tcaaaatcaa caaattttcg ttgatattat
     7981 gagcgttatc atgtcagatg aaaatatcat gctggcatac agaaacatta aaaagaataa
     8041 agggagtaat actaaaggga cagataaaca gaccatacaa aacatagaac tgatgtctga
     8101 aaaagagttt gttcaaaaaa ttaaagatat gttctgctgt tatactccaa aacctgttaa
     8161 gcgagtgaat atacctaaac caaacggaaa gttacgtccg ttaggaatac cgaccatttg
     8221 ggatagaatt attcagcagt gtgtcctaca agtattagaa cctatttgtg aagcaaaatt
     8281 ccataacaat agctatgggt tcagacccaa tcgctcggct catcacgcca tagctcaatg
     8341 ttacagattg atgaaccaaa gcaaattgca atacgttgtg gatatagaca ttaaatcatt
     8401 ttttgataat gtaaatcatg caaaacttat taggcaaatg tggacaatgg ggatacgaga
     8461 taagcattta ctaggaatta tccgtgccat gcttcatgct cctattattc taacagacgg
     8521 aaaaatagaa cacccaaaga aaggaactcc gcaaggagga atactctcgc ctttactatc
     8581 aaatattgta cttaatgaat tggactggtg gatagcttcg caatgggaag aaattccaac
     8641 caaaagtaaa tcagcacgag tattagatag gcgagataaa ggaaaaggaa ttgacaaagg
     8701 caataagtat aaagaattgc gtaaatcaac cctaaaagaa atttatatag tacgttatgc
     8761 agacgatttt aagatattct gtcgaaagag gaaagacgct gataaaatct ttcatgctgt
     8821 tatacaatgg ttagaacaaa ggctttcttt agatataagt gaggaaaaat caaaaatcgt
     8881 aaatcttagg aaacaaaaat cagagtttct tggatttgag atgaaattgg ttcgcaaagc
     8941 tgataaatat gtggtgcaat cccatatgag taaaaaagct atgaacaaag cggaaaacaa
     9001 tctaaaggag cagattaaac gaatacagca ccctgctaat gacagagaac aagcaaaaga
     9061 aatcagtatc tataactcta tggtagtagg catacataac tactataata aggcaacgct
     9121 catagccttt gactgttcaa aagtcaatta cattataagc aactggattg ataacagatt
     9181 aaatgtaaca aaacaaggag ctattcaaaa caaatatcta tcaaaaaaat atggaaaaag
     9241 tcagcaaata cgctggttaa acaactgtcc tattattccg attggatatg taaaacacag
     9301 caaagctata tctattaaaa atgaaatatg taagtttacg ccgaaaggac gagagctaat
     9361 tcataaatcg cttgatatag atgtaggggt acttgttcaa cttatgaaaa atcccatatt
     9421 agatatgagt gttgaatata atgataaccg aatttctaaa tatacagccc agcttggaag
     9481 atgtgctgta ctaggagttt cactatcctt tcaagaaatc cattgtcatc atataaaacc
     9541 tatttcagac ggtggcacgg ataagtttca aaatctaatt atcgtccatg agtctataca
     9601 caagctgata cacgcaacat cacaagaaat aatcagcaaa ataacaaaca aatttaaact
     9661 caataagaaa caaatatcaa aaatcaatgc gttgagaata aaggtcaaca atggtgttat
     9721 tactgtttaa cttgaaaaat atatagcaag taagaaaaag attgatggaa cgccgtgtgc
     9781 ggtgaaagtc gcacgcacgg tgtggagcgg gggaaaactc ggagattacc tcaaagaatt
     9841 atctatcgct attggagctt gtcagccagt atcttacggt cagtcaagta tcgggcgagc
     9901 tggctcagaa gataatgaat gaagctctga aatatcaagg ctgggactat gtgtacggcg
     9961 ggagcaatcc taacacttct tttgattgtt cggggctggt tcaatggtgc tacggcaagg
    10021 cgggcatttc attaccgaga acggcacagg cacagtatga cgctacccag catattccgc
    10081 tttcacaggc acaggctgga gatttggtgt tcttccacag cacctatgac gcaggaagct
    10141 atgtaacgca cgtcggaata gtgcgtccag agggacgaaa gttagaagta gattaaagaa
    10201 agggggacag aaaataaggc actaccccgt aagataacaa gggaaaccac ctgcctaacc
    10261 gaaaggcgaa agctgtacgg gaaaatagca cggcaggaaa gcagaaagtt gttcaaagac
    10321 aatagagcac gactgaactg caaggttaag tgaatatgag gataaaacta gatttgttga
    10381 atgtgagttc caaacctctg ttacgtgtgg acacaggaaa cttgtctgaa acctgtggta
    10441 tgagtaacgc tgaaaataaa tgcctttcag tgggttatca attaactcat acggtacgct
    10501 ggagaaccag tagtaacgga acgaaagcat atccgacaat tcacactagc ccactacttt
    10561 cgtcaactgg agattaccta aaccagaatg cctacaatgg ctatgcgtaa tgctcttgta
    10621 gtgataaatc acaaggctat gctaagtgag atgacgctga aaatctggca aggtaacgga
    10681 gctttcatag tagtctgaga accctgaaaa gacagggaaa gccgtaaaat cggatacggg
    10741 aaaaccgttc acatggcgaa ggaaagcagt cttagcgaat taaaattaga aattgattag
    10801 ggaggaaaac ctcaaatgaa acaaacaatg gagattttaa ccaaattaca ggaaaattca
    10861 aaaaagaacc atgatgaagt atttacaagg ctctatcggt atttactccg tccagatata
    10921 tactatgttg catatcaaca cctctactcc aacaaaggag caggaacaaa gggtgtaaca
    10981 gacgacacag cggacggttt tagtgaaata tatattgaaa atatcattga agccttaaaa
    11041 aatgaaatgt atcaaccaaa accagtaaga cgtacataca tcaaaaaatc aaatggcaaa
    11101 atgcgtccct taggactgcc tgtctttact gataagctga tacaggaagc aatacgcatg
    11161 atattagaag caatctatga gcctattttc tcagactact ctcacggttt ccgaccagta
    11221 agaagttgtc atactgctct tgctcaaata aaaaaagaat ttacaggagc acgctggttt
    11281 atagagggcg acataaaagg gtgttttgat aacatcaatc atgcggtact tgtggaaatt
    11341 gtcaatcaga aaattaaaga cgcacgtttt ctgaagctca ttcgtttatt cttaaaggca
    11401 ggttatatgg aagattggaa ataccacgaa acatatagcg gttgccctca aggtggtatc
    11461 atttcgccta ttcttgcgaa tatctacctt aacgaattag accgtcacat aatgaagata
    11521 aagaaagagt ttgatgtggc aacaaaggca cgttatacac cagaatatac aaaactggta
    11581 ggactacgcc aaagattaca caacaaaatt aaaaatagca atggtataga aagagaaaag
    11641 ctgattgaag aatataaaac tgcaacagct caaatgctca aactaccagc gaaacaatgt
    11701 gacgacaaga aaataaaata tgtgcgttat gctgatgatt tcctaatagc tgtgaatggc
    11761 aatcggcagg attgtgagaa gattaagcaa gaacttacag aatttataag taccacatta
    11821 aaaatggaac ttagtcaaga aaaaactctg attacacaca gtaatactcc tgctcgtttt
    11881 ctcggatatg atgtcagagt acgccgtgac cagcagatta aaccaaaagg aaaattcaaa
    11941 acccgttcta tgaataacaa ggtggaattg agtattccat tcaaagacaa gatagagaaa
    12001 tttttatttt caaatggaat tgtaaagcag aggtcagaca atgggaaatt agaacctata
    12061 caccgaccac aactgcttaa caggacagat ttggaaatag tgactattta taatgcagaa
    12121 ttaagaggta tctgtaatta ttatggattg gcaagcaatt ttaacaagct aatctatttc
    12181 aattatctta tggaatatag ctgtttgaaa acacttgcag gaaagcaccg ttccaaagtt
    12241 tctaaaatta gagctatgta taaagacggt acaggcaaat gggctattcc ttatgaaact
    12301 aaaacaggaa taaagaaaat gtattttgcg aattatgctg actgcaaagg aaagaagttt
    12361 actgatattg ttccacaaac agcaaaaaat tattcccatg acgtaacaac attagaaagc
    12421 cgattaaagg cgaagatatg tgaagtatgt gggtgtacgg atagcgacag atacgaaatt
    12481 catcatgtaa acaaggttaa aaaccttaaa gggaaatcag aatgggaaaa ggtaatgata
    12541 gccaaaagac gaaaaacaat cgtggtatgc cacaagtgtc acatggctat acatcatggc
    12601 gaaaagaaat aacctgtaat ggagcaaaga tggagagccg tgtgcattga gaaatgcaag
    12661 cacggttcgg ggagaggact gcacaaacct accttagaaa taaggaaagg cggtgctttc
    12721 ctactctact atgtagggaa caatcagatg tatcacgctg gcgacccgat aggctacgct
    12781 gatttgaaca atagctactg gcaacagcac cttatcgggg ctggcagaat taagtaatag
    12841 aaagaaagga atggaaatat catgttcaag aagaaagaaa atccgataaa ggaaaagaaa
    12901 atccgcacta tgaaagtggg gacgcataag aagtccgtta ttgccctctg ggtggtgctt
    12961 atcgcaagcg tgagctttgg tgtgtataag aattttacgg ctattgacca gcacaccacg
    13021 catgaggtag aaaccataca gctacgactt aacgatacca acgggataga aaattttgtg
    13081 aagaatttct gtaaatccta ctacacatgg agcaacagca aagaagcaat cgaagcaagg
    13141 acacaggcta tcaatgccta tctgacacag gaattgcagg atttgaatgt tgatacggta
    13201 agaacggata taccgaccag ctctacggtc acggacgtac ttatctggga cgtggaacag
    13261 tctggggaaa acgcattttc tgttacctac gaagtagatc agcagataaa agagggcgac
    13321 cagacaagga atgtatcgga aacctatacc gtgactgtcc atgtggacgc tgacggggat
    13381 atggtgatta tccagaaccc gacccttgcc cctgctatgg aaaaatccag ctatgaacca
    13441 aaggcacagg aagcggacaa cagcgtggac gctgatacgg tcaatgacgc tacggcgttt
    13501 ttggaaacat ttttcaagct gtaccctact gcaacggaca aggagcttgc ctactatgta
    13561 gagggaaacg cccttgaacc gataaacggg gactatctct attccgagct tgtcaatcct
    13621 gtattcacgg ctgacggcga gaatgtgaga gtgagcgttg cggtgaaatt cattgacaat
    13681 cagacaaagg cgacacaggt atcacaatat gagctgacgc ttcataaaga tagcaactgg
    13741 aagattatag gttaataaat aaataggctt gtcattatat tggcgagcct attttacatg
    13801 agtgaatatt attcattgac aatcgttcat tcgtgctgta taataaccaa tgaaaggagc
    13861 gatagcatga accaaaataa ggaaaattca aaaaaaactt tcgataaaca ggctatttct
    13921 tatgatacgg atatggtagg tgaacatgca agaaatctat atgctccaat tttaaaaata
    13981 ttgaagcaag aacatcatgt tggttcactt cttgatttag ggtgtggaac gggagctttg
    14041 ttagaaagca tatttaacct gaatattaca agacagttat caggaataga cttatctccc
    14101 aatatgattg aagaagccaa aaaaaagatt ggcgataacg tgaaattata cataggagat
    14161 gctgaaaagc taccttttga agatggttta tttgatacgg taatatgtaa tgactcattt
    14221 catcattacc cagcaccgaa tagagtgata aaagaagtat cacgagtatt aaaaaaaggt
    14281 gggcttttcg ttattggtga ctgttggcaa ccagcaggag ctagacaaat tatgaatttt
    14341 tatatgaaac atagtaagag tggtgacgta aaaatatact caaaaaagga aatggaaaat
    14401 ctattatcaa aagatttttg cacagtatta tgggaacgta ttagcaatac ttctagttta
    14461 acaatagcac gaaaatgact gaatattagt cattgacata taatgctctg gaagttatga
    14521 tgaaaaagga ggtgtggaat aatgcgtatt tcaaaagaac cggaagaaag aaaacaagaa
    14581 attttagaaa cggcaatgaa gttatttgca caaaacggtt ttgaaaaaac atctatctct
    14641 gatattgcaa aagaaatagg cgttgctcaa ggactttgtt atagatattt tccgtctaaa
    14701 gatgttttat tccaaacggc gttaaatgag tatgcaaata ttttagtttc taagatgaca
    14761 aaaaacatta acataaagca agatacctta aaagaaattc tcaataaaat gacacttttt
    14821 tcagaacatg aaagtgatct ttattatcaa gtatttcatg acaagcaaaa caaaaatttt
    14881 catgatttgc ttgtcttatg tgtttgtaaa aaattaacac ctattgttca agatataatt
    14941 attcgagcta atcaaaatca tgagataaat atttccgacc cagaaacatg tgctagtttt
    15001 tgtgtttttg gtcagttggg aatattgatg aataatgaaa ttgcttttag tgaaaaaagt
    15061 gacagaataa aaaccttttt taataaccta tttaattttt gatatatccc ctgcttaagg
    15121 cagggaatat ttaaacgcta tatatgaata acattcattc actaaggaga gcttaattat
    15181 gaacagcaag atagatttta ttaacggaaa taccaaaaaa tgtttattat ccatgacgct
    15241 tccaatgatt gtcgctatgt ttttaaatat ggcatacaat ttggtggata gtctttggat
    15301 tggaaactta ttaggtgaac aagcatatgc ggcacttaca aattctacac ctataatctt
    15361 gattttaacc tcaatcggta tgggggcaac aaatggtgtt tctattcttt tatcgcaggc
    15421 aatcggtgca aaagaagaaa caaagaaaaa gcgtgtatta tctacatcgt tttttgtatc
    15481 tgtaatattt tcaatactga ttacaatttt attagaagta tttttaaatc ctattctgac
    15541 tgctttaaat acgccagatg aaatctttga tatggcacga agctacttat ctatctatat
    15601 cttaggttat gtagctgtct atttatattt atatttcaca gcgattttaa gaagttttgg
    15661 aaatacaatg tttcaagctg ttgcaatgct tgtatctacc ctgcttaatg caattttaga
    15721 ccctatactt attaaaataa ttggatttca tggtgcggct attgctacat tgacatcaca
    15781 gattatctgt ttgattttta tgtgtatcta tatttcaaaa aagaaattat tcaagtttac
    15841 tctatctgat tttgataaat tggaaattat gccacttatt aaaaatgctg taccgtctgt
    15901 tatccagcag agtattcccg ctattagcac gacttttctg accgcattag taagcggtta
    15961 tggtatttca gctattgccg gttatggtgt aacgggaaaa ttagaaacca tactattcta
    16021 tccagctatg gcattaaata tggtattgac ttcaatagtt ggacaatgta taggcggaaa
    16081 acgaattgat agagctaaag attatttaaa attatccttg aaatatggaa gtatcacttt
    16141 aattatacta tcactgatta ttattgtttt ctcaaaacaa ttagcagggc tttttgtggc
    16201 aagtgagaat gtagcagtta ttgttaatca gtattttacg atagtcagca taggctatgt
    16261 tctttacaca attacaagct gttgtctagg tacattaaat ggacttggaa aaccaacaag
    16321 aagtatgata cttatgattt tttactatat tgttatccgt attccattag catatatttt
    16381 tgcaaatcta ggaagcggtc tagttgggat ttggttggct attttaatca gccacattgt
    16441 tgcctgcatt gcaagtatta tatgtggtat aggttctatg aaaataaagg agtaaaaaat
    16501 tgattggatt aaaaagatat gatatgaaag cacttttaaa agctggtgca aaagccagag
    16561 gattgtcgtt accagagttt agagccgaga tacagaaaaa cattgacaat gctatgaata
    16621 gtcaagaccc agtggtgcag aaacatttta aaaagtattt tggtaataag atacctacac
    16681 cagaagaata catttacaca atcacaaaga aaactaagat ttaagtgctt atcctgcttc
    16741 ctgcggagca gatcagcagg atagcttatg aaaggaaaaa gaaaacgaga agcctatttg
    16801 cttcccgttc ccttgtattt catgataccg tcaatcgttc cttgaatgat tttgagttct
    16861 tcatctgtca gttcatcaag cgatacgtct atctgtctgc ggattgtaga tttttctgct
    16921 ttctcctgcg gatagaagta ttcatcaaca gagatatgga acattgtcac taaatcatga
    16981 aataactgga agctggggtg tttccctata ttctcaatat ctgcgatatg acgttctccg
    17041 taaaagacct tatcgcctaa gtcattacgg gaaagcccag ctttctctct cgcttctctg
    17101 attgccagtc ccagcggacg gaaatcaaag ctgtgcgtgt ctttcttttt cctcatttta
    17161 aatcacctgt catgagttta tacttcatgg cacatgatta gaatgtgtta aaaacacata
    17221 tattatacgt tagtagttcg tatcaatatt accttggcgg taaataaaaa aaaccgttct
    17281 agggtaatat ctttttccat gtctttcaat ttgattagga cggttttgga taaccagagc
    17341 tgtccttttc ttttgcactc acggtacagc tctgaataag ggggttgtgc tatgattgcg
    17401 tatcagcaaa cacgccagta ttcacaaccg aataaccgcc ttacaatggt tatccagtca
    17461 atacacctta aacatgagtt aaaaattcat atcgcaaaca taacaaaaac agtctgttgg
    17521 tacattcatg tgcttattga ctgtttttgt tatttatgag aagttcaata tttttttgaa
    17581 tttctttctt atacaggtta gcaaatcacc cactcctgta ccgatgtggg gcggaaagag
    17641 ggatagatac cttttacgtc tggacagaga gggggtgaga tgatgaaacc gtctgacttc
    17701 caaaaaacaa tccagtgtca gtttgactgt aaactcaaac gtactgttaa aggcgttatc
    17761 tggaattata aaaaggaatt aaaacgtcgt aaggataaag aaattccttt ctgtgagctt
    17821 ccagaaatcg ttgttgaaaa gctggctgta tgggacgagt acatgagtga ctataccgtg
    17881 tttgaggtat gcggtgttga aatccgagtg cttgatgaag aactctcaga agcattaaag
    17941 caattatcgg aacgcaaccg tgaaaatctt ctgatgtact actttctgga aatgagcgat
    18001 acagaaattg caaaagcaca gaaaatttcc agagcaggag tttttaaaaa ccgttacaga
    18061 gctttacaaa atttaaagaa aacactgaca aaggagcgtg aataaaacat gaaaaaaggg
    18121 tacaagcttc caccttaccg acttatttca tctgctgtgg acgggaatga acagtctatt
    18181 gaaagaatac tggcatttta tgacccgtac atatcaaaat gctgtttgcg tcctctgtat
    18241 gatgaatacg gtaatgttta tatcgtagta gatatggagc ttaaagggcg tatcagagaa
    18301 gctattatca aaatgatttt aggcttcgat attggtactg tgccaataga agaataaagc
    18361 aattatggca gggcatgatt tgttgaaatc ccctctttcc tgtcctgccc tctgctttta
    18421 cacatgagag cctatggctt tcaccactgt tctttgacaa ctgaataaag cagacagata
    18481 cgtttgtgat acagcgagcc acgggaactg tacgccacga cctttccaaa agagagcgag
    18541 cgacccatgc agtgatccga gagcgaccgt tggaaaagtc gctttgccac gacctgtatt
    18601 cacaggataa tgatacgtcc cagaggtggt tttgctcata ggaatgagat tggttgagat
    18661 accagcggag cttttccaga gccgtctgtc tgcttccaaa agacacacag taaagggggt
    18721 gcatattatg aacaatactg atgtgcctat ctgggaaaag tacacgctga cgattgagga
    18781 agcgtcaaaa tacttccgta tcggagagaa taaacttcgc cgtttagctg aggaaaatat
    18841 cggctcaaac tgggtcatta tgaatggaaa ccgtatgcag ataaagcgaa agcaattcga
    18901 gaaaattctt gataagttgg acgcaatctg atgaaagcaa gccttaaata tggtataatt
    18961 atactatcga gtttaaggct tgctcctttt acgaaaggag cttcctgtaa tggcaaaaga
    19021 agtcagacga gataacaaag gacgtatttt acgcacagga gaaagccaga gagccgacgg
    19081 aagatattta tataagtgta ccaacgcatt aggagaatct gtttcgcttt attcatggaa
    19141 actcgttccc acagacaaga taccaaaggg aaaacgtaag gatatttcct tgcgagaaaa
    19201 gattgaacag ttgcagaaag accttaatga cggtatcgac cctgcgggaa agaaaatcac
    19261 ggtatgccag ctttatgaca aaaagaacag ccttagaaag aatgtcaagc acaatacggt
    19321 aaaggggcgt aagcagttta tgaacctgtt gaaaaaagac cctttaggaa gtatgacgat
    19381 tgatacggta aagctgtccg acgccaaaga gtgggcaatc cgtatgagtg aaaatggcgt
    19441 ggcgtacagt tctatccgca attataagcg ctccttgaaa gcgtcgttct atcttgcaat
    19501 acaggacgac tacatcagaa agaacccgtt tgattttaag ttgagcgacg ttctggacga
    19561 cgataccgag gaaaaggtag tgttgacacc agagcaggaa gccagcctat tgtcctttat
    19621 gcagtcggat aagacgtacc gtaagtatta tgatgaggtc gtcatactgc tggaaacagg
    19681 cttgcgtatt tctgaatttt gtggattgga cttaaatgta gctgttgaca tgcgtaacag
    19741 gtcaatcctt gtagaacacc agttgctaaa ggataaggaa atcggttatt acatttccac
    19801 acctaaaaca aagaatggta gccgacaagt gccaatgagc aaaaaggctt atgaagcatt
    19861 taagcgagtt atcaagaacc gtgagaaagg catatcgttt acagtagatg gttacagccg
    19921 tttcctgttc cttaatcaaa aaggattgcc taaagtagct gggaattatg acggtatgtt
    19981 aagaggtctg gtaaagaagt ataacaagac acatgatgaa cctttaccgc acatcacacc
    20041 gcatacattc cgtcacacgt tctgtacgaa tatggcgaat aaaggaatga acccaaatac
    20101 attacagtac atcatgggac acgccaatat caccatgacg ctgaattact acgcacatgg
    20161 ttcttatgct tctgcaaggt ctgaaatgga caggctttgt gcatagtggt aaaaagaata
    20221 tttaccacaa aatttactac ttccgaacgg taaaatacat agagatataa aaatctatgt
    20281 gaagtgcttg accctatgaa aaatgcctta gaagcctata aaataaggct tcaagggcat
    20341 ttaagaagat ttaaaaagat aataggaatt tatgataaga ttttaagcaa tacaaattta
    20401 tatgtaatac gtctaagaga tttttatttt ctagttttaa ttattttaaa caacagatat
    20461 ttttccattt aatgaatctg acaatattaa aggagcttca gtagcagaaa taacatcatc
    20521 taatgtgaaa gctggattta tttctttaag taaaattcca tctgatgtta cttccataac
    20581 tcccatttca gtaactatca aatctacagc atttgttgca gtaagtggaa gagtacaatt
    20641 atttaatatt tttgcagaac cttttgaagt atgttccatt gctacaataa cttttttagc
    20701 tccagttact aggtccatag ctccacccat acctggaacc atcttacctg gaatcatata
    20761 gtttgctata ttgccatatt tgtcaacctg aagtgcgcca agaacagtta tatcaacatg
    20821 acctcctctg attattccaa aagaagtagc actatcaaag aaacatcctc caggaagtat
    20881 agtaactggt tgaccacctg catttacaat agtttcatca cttgaatttc catcttcggc
    20941 tgaacctaaa cctaaaaagc cattttcaga ttgtaagata acgtttacat tatccggaat
    21001 ataatttgct actttggttg gtagacctat tccaaggttt acaacggctc cgtcttttaa
    21061 ttctttagat actctatttg caatatattc ttgcatttct aatttatcca ttataaatta
    21121 cctccttcaa cgatgtaatt cacaaaaata cctggtgtat taacttcatt tgggtcaata
    21181 tcaccaattt caacgatttc atctgcttca actattgtaa ttttggcagc agatgccatt
    21241 aaattattaa aattgttcat agagccttta taaactagat tacctgcttt atcgaccttt
    21301 gatgcaaata gaagagcaac atctgcataa attggttttt caagaaggta ttctttgcta
    21361 tcgacaacaa ttttttgctt tccctcctca acaagagtac caataccagt cggtgtgagt
    21421 atacctccta gaccataacc agctgcacgt atttgttcag caagagttcc ctgaggaact
    21481 aactcaacat ctgtttcatt gttgttcatt tgtcttccag tttctttatt taatcctaca
    21541 tgagaagcaa ttatcttttt aaattgctta tttacaacca ttttgccaac tcctttgtca
    21601 ataaagccag tatcattgca aattagtgtc aaatctttta tatttttact acataaataa
    21661 tcaattaaat tttctggtga accattggcc atgaatccac caaccattat tgtatctcca
    21721 tcttttacat gagatagagc ttcatcaatg ctaactattt tattcatatt tcctcctatc
    21781 gtgaaaccac cattgatatt ccttgaccac caccaataca aagtgttgca agtccagttt
    21841 caactttacg tttttgcatt tcataaatta aggtaacaag tattctagct ccacttgctc
    21901 ctattggatg tcctaatgct attgcaccac cattaacatt taactttgat gaatctattt
    21961 gaagttcatt tttaacagct aatgcttggg cagcaaacgc ttcgtttgct tctattaagt
    22021 ctatatcatt gatgctaagc ccagcttttt tcagtgcttt tctagttgca gggattggac
    22081 cagtacccat gacttcaggt tcaacaccag ctgaagcata ggattttatt ttagcaagtg
    22141 gtctaatacc tagttcgtct gctttttgtt ggctcattag tattaacata gctgcaccat
    22201 cattaatacc tgaggcattt ccagctgtta cagtgccatc ttttttgaat gcaggtttaa
    22261 gtttagctaa accttcaaat gtcataccta atttaggata ttcatcttta tcaatagttt
    22321 ctatttttcc tcgacgtatt aaaacatcta ctggaacgat ttcttcttta aagcgattgt
    22381 tttttatagc attctcagcc ttattttgac tttctaatgc caatttatct tgcatttctc
    22441 tagtaaattc aaatttagtt gcaatatttt ctgcagttat tcccatatga tactgattga
    22501 aagcatcaat aaggccatct gttagcatac tatctaccat ggttatgtca cccattttac
    22561 taccaaagcg agcagttgga acgatataag gagcttggct catattttca gtaccacctg
    22621 caattaccac atcattttca ccagatgtga ttgattgggc agctagctgg acacttttaa
    22681 gccctgaacc acataattta tttactgtgt agcttggaac agaatttggt atacctgcat
    22741 ttatagcaat ttgtctagca acattctgtc caagccctgt ttgaagaaca tttccaatta
    22801 ttacttcatc tatttcagat aaattaagtc ctacacgtga tatcgcttct ttaacagcga
    22861 tagttccaag ttgaacagct gaagtatttt taaatacacc tccaaaactt cctataggtg
    22921 ttctgactgc tgatacgatt actacatctt tcatatctaa tagttacctt tcttgaatga
    22981 taattaaaaa ttttctgaat aaagaaatta gggaacacta taataaagta cttttttaat
    23041 acaagcttgt ttttaagtat ttcaattact tttattccta atgctttagg ttttcctgtt
    23101 tctaattata gattacggcg aaaaaagcgt tttgtctaag tctaattttt tatatagtgt
    23161 ataagaaaaa tttataggat aaaaatttat agtagattta gaaaaatatt ttgttaaaat
    23221 attaatgaaa ttatgttgat tttcctataa aatatcatta gaagaaaaaa tataatctaa
    23281 attatacttt tggggaaggg ggtttaaaat ggatataaaa cagttgaaat attttgttga
    23341 aatagtgaaa tctggtttta atttatcaat agcatctaag acacttcaca tatctcaacc
    23401 agcattaagt caaattataa aaaattttga agaaagtgaa gatgtatatt tatttgaaag
    23461 gtataaaggc aggttaaatg ggttaacacc agcaggagaa agattttatg taaatgcaga
    23521 acatatcata aatgaataca aaaatatgat ggaagattta agagaagatt cagttcaatt
    23581 taaaggaaaa gttagaatag gaatacctcc acttatactt ggaatagcat tttcagatgt
    23641 agttgcacag ttagttgcaa ataatccaga tatagaattt gatatagtag agaagggtgc
    23701 atatgactta aatagaatgc ttatcttaca ggaattagat tatgcagtat tgttacatcc
    23761 acataaaatt gataaaagtg tagtaactga acatgtgctt caagaagatg aacttacagc
    23821 atttttaaat ataaatcatc cacttgctaa gaaggataag atagattgga acgatttgaa
    23881 tgagcagtta cttgcaatat ttaatcctac ttttatgata catcataagc taatgcaaaa
    23941 atttactgat gaaaatgtta agttaaaaag atatataatg tctggttcat gggatttttt
    24001 gttgctatca accacaaatt ctgattttat aacaattcta ccatcaccag ttcatgattt
    24061 ttttgaaaat agcaaaatta tagaaaagcc ttttaatcat cctattacat ggaaagttat
    24121 attatgtaga cctaaaaaag aacgttatag ccatgtagac caacatgtat ttaaatttat
    24181 tatagatttc tttagtaaaa agaactctta aaaatgttat taaaataaca aataaataaa
    24241 tcaattttta ttataataaa ctattagttt ttcatctata tgtttgagag caataatagg
    24301 ctttacataa catggtagag tagtatttaa agttataata tacaaaatat gtattttttt
    24361 aaacgaaaaa taaaaacagt gtatatcttt agataatcac tgtttttatt ttctatataa
    24421 aatttgttaa gtattactag aaaatttttt gcttattata gtcaaactca tgactgttaa
    24481 aaatataagt aatcctggaa atacagctaa atataacttg tcaaaaatat gtctttgagc
    24541 atcttgaagc atattacccc atgatgcaag aggcaattgg attccaagac ctaaaaaact
    24601 aagagcagat tcagttaaga tagcattagc aatatttaac gaaccagcaa ctacaatagt
    24661 ctcttttaag tttaaaacta tatgtcttaa tagtatattt ctagtcttga taccagtagc
    24721 tttagcagct agacagtatt cattttcctt tatttttaat gtttcgccac gtacaattct
    24781 tgaaacttcc atccaactta agaatccaat aattagtata atagtggaaa ctttaggtgt
    24841 tagataagta tttaatacaa tcaaaactaa gaaacttggt atactcataa gcatatccac
    24901 taatctcatc aagaattggt ccagcttacc tccaatatat ccactaataa cacctacagc
    24961 agtaccaaat actacagaaa taagcattga taaaatacca acactaagtg aaatccttcc
    25021 accataaaga gctctagaga agtaatctct accaagttcg tctgtaccaa agatatgctt
    25081 taagctaggt tcttgaagtt tagaagtagt atcaattgca ttagagtcta tatttaatat
    25141 aaaagaagct ataattaata tgattattat gctaagagta atacatgcaa aagcaaagga
    25201 tttatctttt tttaattttt ttaagatact tgtaaacaca actagaatcc tcctttgcta
    25261 gattttattt tagggtcaat taataagtat agtatatcag caactaaatt acctaaaatt
    25321 aaaaatagtg ctgataacat agttattgcc ataattacag tataatctct tgaaaaaatt
    25381 gaatcaatca ttaatcttcc catacctggc caagagaaaa ctacttctgt aacaaatgca
    25441 ccagtgacta atttttgtat actcatgcct aggattgtaa ccaatgatgt cagtgaattt
    25501 ttcaagacat gtttaaatag tatgactttt tctgataatc cttttgctct tgctgtaata
    25561 acatattgtt tttttaattg ttcatttaca ctagcttcta cataatttgt aaaaatagca
    25621 gtattatata gacctaaagt tattacaggc aaaactaaat gttttactaa atctccaata
    25681 ctatcatttc caatagtatg catacctcct gatgggaaaa tgttaagttt aactgaaaaa
    25741 attgaaatga gtatcatacc tatccaaaaa gaaggtatag aaacacctat ataattaaaa
    25801 acagatgata ctttactagt tattgaattt ttatttacag ctaaaaatat tccaagaggt
    25861 atagctacca atattgaaaa tatcaaagaa gtacccataa gaataaatgt atttcccatt
    25921 ttttccataa tttgttctgt aacgggcata tggtttatat aagaaatacc taagtttcca
    25981 cttaaagtgt ttttcaacca gtttaaatat cttatatata ctggtttatc aagtcccata
    26041 ttaaccctta tattttcaat atcctgtgaa gacattaaag gatttatata tgcatctgct
    26101 gggtcaccag gagctaattc taaaagtcca aatgataata tagatattaa gattaacata
    26161 ggtattaaaa cttttactct attcaatatt aattttaaca taagtaaatt ctcctaatta
    26221 aaagagatgt ctcgttttaa aataataaaa caatattatt tttagacatc tccttttcta
    26281 attaataata taaaatttta catcaattat tctacataca gtttagacca atcttcaaat
    26341 aatattgcag gagatggctt agcatctttt attcctttta gatttttttg agctgccatt
    26401 aaattttgtt cataatctat agtgtaaata ggcgcatcct tagatatatc ctgttgtatt
    26461 tgcttatata tttcttcacg tttttccttg tttaactcag taaatccttt ttcccataaa
    26521 gcatctattt cagcattaga atatttagtt tggttgcaat attgaccagt ttcaaacata
    26581 cctctatatg ggtttggttc taatccccaa gcataaccat ttacatacat atcacattca
    26641 gtgctattac taaatagtat attgaagaat gccttacttt cataaggaac tatttcagct
    26701 tctataccaa tttttttcaa ctcttgttga gctactaagg catagttttt atgcccaaat
    26761 ctacctgtgt tataacctat ttttaattta tcaattttaa caccactttt atccaataag
    26821 tctttagcct tatttgtatc ttggtcatat ccttcaacac cttcttctgt atagaagtct
    26881 gcttctggaa ctaatataga tttagcaggt acagaacctt cttttccata tgctgattct
    26941 atcatttcat ttctatttaa ggcatatgat aaggcttgtc ttacttcttt gttagccatg
    27001 tttgatatat tttggttaaa tacaatgtag tttaatcttt cttcactata agtataagtt
    27061 tgtaagtttg agtttgattt tgccttttca tatccttcag cagatgtctt cataagtgaa
    27121 atttcgccat tatttaaagc tgcttcttga gatgcttcat taggaattat ttttagcgct
    27181 atagaatctg ccttaggttc tccaccaaaa taatctgcat tcttttcaaa tactatgctt
    27241 tcaccttttt tccattcctt aaacttgaat gcaccagaac caactggatt attatttttt
    27301 tctgacttag ctatatttga ttctccttca aacacatgtt ttggtattgg agaaatttta
    27361 gatataccat ataagaaaga ttcacttgca gttggtaaag taatcttaac tgttaaatca
    27421 tcaatttttt ctactttaac tggtttctca cccaccaata agtattgtct tgatggtgaa
    27481 ttttgttttt cgtctaaaac tgtattaaat gtaaataaga catcttcagc agttattggc
    27541 tttccatcat gccattttaa attggatttt aattttatag ttaattcctt actatcttta
    27601 aaatctactt tttctgctaa ataatttact aaatttcctt tttcataagt ataaagagga
    27661 gcataaacta tatttgatgc aagagagtct tctttaacgt ttgcaaaagc tccattgatt
    27721 atatctgggt cacttgccat aggtattaca acagttccac cagatttgct tccattagac
    27781 ttgtctttat cattggaagc acaggctgta aatgtaagca ttaatgatga aactaagatt
    27841 aatgatgcca attttttaaa tttcatattc ttataaaacc tccataaaat aatatttaac
    27901 acatattttt tattgtataa tagtaatcat tattaaatca atatatatag
//
LOCUS       DAEPUT010000051        27764 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.053, whole genome shotgun sequence.
ACCESSION   DAEPUT010000051 DAEPUT010000000
VERSION     DAEPUT010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27764
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.053"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(109..1296)
                     /locus_tag="KRL22_002362"
     CDS             complement(109..1296)
                     /locus_tag="KRL22_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HBH1272843.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(1498..2769)
                     /gene="brnQ"
                     /locus_tag="KRL22_002363"
     CDS             complement(1498..2769)
                     /gene="brnQ"
                     /locus_tag="KRL22_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH1272844.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            complement(2910..3563)
                     /locus_tag="KRL22_002364"
     CDS             complement(2910..3563)
                     /locus_tag="KRL22_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH1272845.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     regulatory      3892..3993
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            4066..5409
                     /locus_tag="KRL22_002365"
     CDS             4066..5409
                     /locus_tag="KRL22_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH1272846.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            5588..6952
                     /locus_tag="KRL22_002366"
     CDS             5588..6952
                     /locus_tag="KRL22_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1272847.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(7130..8995)
                     /locus_tag="KRL22_002367"
     CDS             complement(7130..8995)
                     /locus_tag="KRL22_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HBH1272848.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEDSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINDILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(9231..10448)
                     /locus_tag="KRL22_002368"
     CDS             complement(9231..10448)
                     /locus_tag="KRL22_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1272849.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAILIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(10648..11511)
                     /gene="aroE"
                     /locus_tag="KRL22_002369"
     CDS             complement(10648..11511)
                     /gene="aroE"
                     /locus_tag="KRL22_002369"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH1272850.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGIGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVSECIVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(11593..13515)
                     /locus_tag="KRL22_002370"
     CDS             complement(11593..13515)
                     /locus_tag="KRL22_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1272851.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLSMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(13579..14427)
                     /locus_tag="KRL22_002371"
     CDS             complement(13579..14427)
                     /locus_tag="KRL22_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBH1272852.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            14840..15721
                     /locus_tag="KRL22_002372"
     CDS             14840..15721
                     /locus_tag="KRL22_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1272853.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLRERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(15929..16792)
                     /locus_tag="KRL22_002373"
     CDS             complement(15929..16792)
                     /locus_tag="KRL22_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HBH1272854.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(16947..18881)
                     /locus_tag="KRL22_002374"
     CDS             complement(16947..18881)
                     /locus_tag="KRL22_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HBH1272855.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(18993..20006)
                     /gene="galE"
                     /locus_tag="KRL22_002375"
     CDS             complement(18993..20006)
                     /gene="galE"
                     /locus_tag="KRL22_002375"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBH1272856.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(20030..20899)
                     /gene="galU"
                     /locus_tag="KRL22_002376"
     CDS             complement(20030..20899)
                     /gene="galU"
                     /locus_tag="KRL22_002376"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH1272857.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(21097..21417)
                     /locus_tag="KRL22_002377"
     CDS             complement(21097..21417)
                     /locus_tag="KRL22_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272858.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(21407..23398)
                     /locus_tag="KRL22_002378"
     CDS             complement(21407..23398)
                     /locus_tag="KRL22_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272859.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(23521..26064)
                     /locus_tag="KRL22_002379"
     CDS             complement(23521..26064)
                     /locus_tag="KRL22_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HBH1272860.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESVSQTIHNEYK
                     KLCGLEELHSVEGYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGVKEEIDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEVEQEEENLNDISPDIILDKPVENHQVKSEEMEQNEL
                     KEIKQKEPSQHIEEERNVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(26342..26676)
                     /gene="rnpB"
                     /locus_tag="KRL22_002380"
     ncRNA           complement(26342..26676)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KRL22_002380"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            26808..27485
                     /gene="srtB"
                     /locus_tag="KRL22_002381"
     CDS             26808..27485
                     /gene="srtB"
                     /locus_tag="KRL22_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HBH1272861.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(27645..27719)
                     /locus_tag="KRL22_002382"
     tRNA            complement(27645..27719)
                     /locus_tag="KRL22_002382"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27685..27687),aa:Thr,seq:tgt)
BASE COUNT         8953 a         4827 c         3111 g        10873 t
ORIGIN      
        1 tatggataag cttcttttta attgttaaaa agataaaaat atatttgatt taacagaaaa
       61 agagtgcctc ataaactaaa aagttcattt tgagacacgt ccttaatatt aataaattaa
      121 ttggcttaaa attactgatt gataattata aagtacctct gttaaaggag taaattctga
      181 accgattcca aatcttaatt ctgtaaacgc ctctaaataa tctgggtcac atacatcttc
      241 ttgtgttaaa tcttgtttca ccatttcagt agcaagataa attgctactg atggtagaaa
      301 agcatccatt ggcataggat atccaccaag tctatttgac atgccaaaag ccttagcctt
      361 ttcacttatc atgtcgttta ttttatcata attttgagca tctttttcag atatttttag
      421 acccataaca ctaggatatg tttgtattgg tgatggattg ctttgctctg caactatata
      481 ctttaattct aaagccttag tcaatataac ttcatccata tactcattta caccaaatac
      541 atttatatct tttccatatt ttttaacttg tttttcaata tcttcattta aaaactgctt
      601 aactttgttt ttgtcttctt cagtatttat atttggagta ttaacttgta caaatggcaa
      661 tcctatattt ttgcaagtct ctttaatcat ttctaatctt ttggctatat taacatcttt
      721 caaatcatct gtagaggcat aatgaataaa agcttttgct cccatttctt ttgaacgttc
      781 agctaatact tttcctcttt cctctgcact aacccctaga ttcacatcaa caaattggct
      841 taattggttt ttatcatctc ccataggggc agaaatagtt attatttctg gacgcttttc
      901 ctttaccttt tgtaaagcag gtaaaagccc tgcttggtca gttgaaacta caatagcctg
      961 aacttcttta tcgtcagcca actttactat cttattaata gcactgtcta tattagaagt
     1021 aaaattctct ggcaatacaa catgctttat agtttgttta actttagttt gaccatcttt
     1081 gtctttatca attttattct cttcctcata ttcttttgcc atctcttcca ccatattgta
     1141 ttgtacttta ttttcagata atggttgagt taccactgca actttaaaat catctataat
     1201 tttctcttta tctttcttgc ctacaagtaa actacaacct gtaagtccaa taattaaaca
     1261 tatggatagc ataaatgctg ttatttttct aagcattaat taaaacctcc taaatttgta
     1321 cattcttatc actattacta attttatcat acttcaaaga aaaattatat tataaaaaat
     1381 tatatacatg ctattataat ccaatctaaa aagtactatg ggtagattag gtttagatta
     1441 aacctaccca tagtactaaa aattaatata ttataaaatt aaattaatta caaattatta
     1501 tgctacttgt ttgttgcttt ttataaagtt accaactatt ccacccaata tagctggtat
     1561 tacccagtta aagcccaaac ctgcaagtgg caagctttgt ataaatggaa cagctcctgt
     1621 cattccattt atagctgata ataaactaat cactaatgta acatatgctg cacctttaaa
     1681 agcattatca ttctttatat gtttaccagc caactccata acaactattg ctaataaaac
     1741 aggatatata gtttgtagga ttggaactga tatggctatt atagaatcaa cacctaaatt
     1801 tgatataagc atactagcta cacatatacc tataaccagt tgtttataac tcgccttact
     1861 tattccttca aaataagttg atattgatgc tgttaaacct gtagaagtag tcagacaggc
     1921 aagtgccaca attacaccta aaattacctt tcctacttga ccatataaca atatactagt
     1981 tatttcaact aataaagatg cttgaggtat actagtatca tataaagttg aaactgttgc
     2041 acctaaataa gtaagaccac catatactac tgctagaaat acacaggcta caaaaccagc
     2101 tttaatagtc attcctattt ggtctttatc tgatgtatat cctttagcta ttatagacat
     2161 caacattata gttgccatag atgctgcacc tagagcgtcc attgtttgat aaccttgtga
     2221 tataccttca ccaaatagat ttttatctat catatgctca ggactcatag gtcctgctgg
     2281 agaaattata ccctttacta ttaaaacaaa taatactaat aataacgctg gagttaaata
     2341 cttacctatt atgtctataa ccttagaaga cctaatagta aatgctaaag ttagcccaaa
     2401 gaagattatt gaaaatacag ctttagctac tggaccatgg tctccaaata taggcataat
     2461 acccatttca tatgttgttg cgcaagttct tggtattaca agaagtgcta aacatgctag
     2521 agcagctaca ctcattactc ttgctaaccc tttaccagct ctcctaagta catcatccat
     2581 gcttccctta catcttgctg ttgctataat aacaagcatt gctataccag catctgcaac
     2641 aacaaatcca ataagaggaa ttaaccagtc tttgccggat tccatcccta aaaatggagg
     2701 aaacataaga tttcctgcac caaagaacat agaaaataaa gcaaaaccaa ctataaaaat
     2761 atctctcatc tgcttactca cactaaatta ccccctttga aaatattttg aatattaaga
     2821 taatcttact ttattttcag aaaaatgtca atctggtaaa aattcacaca ttgttaacgt
     2881 tttcccaatt tattttatga atattttttt cattttatga taattcccat caatttcgtt
     2941 aaatcaattg cttgtgacac atcaaaaatt gctcctctaa tatcatctat accaatctca
     3001 attccctcaa tattattagt agtaaaatct atgccagaaa gtttagttcc attaaagttt
     3061 gcttttttta aatttgtata ctcaaatact agattgtcac cttttacttc ttgaaataca
     3121 gaattttcaa aatttgaatc taagatagaa actatcttaa atttagagaa tgaaaagtta
     3181 gaatacttac ctaaaacatc cttgaacaaa acgtttttaa gtatacaatc atcaaatcta
     3241 actcctatca atttactatt tttaaattca actctgtata tacttcctcc atcaaaaaat
     3301 gtatttgata aattgcagtt ttcaaatacc acatcaagta aatcaatctt ttttaaatta
     3361 caattttcaa aagacacatt tctaaatata caagattcaa agctaactct tacagaatct
     3421 aaatcactta taacttcatt ttctataatt ttattaaata ttttttcatc attaaatata
     3481 tcttcaagta tatcttcaag attttcaata atttctaatt ctcctgtaaa tttaggtttt
     3541 tgcactttaa taattttagt cattttcccc tccactataa attatattat ttttgatatt
     3601 atttttttta atatattaac ttaatataca tatttgatat attaaaaagt ttttacgaaa
     3661 tatccatgta ttcagtactt ttataattat atcacaaact catttataat aaacttccat
     3721 taatagtata aaacaagtta gaataattga cattatactc atacatattc aattattgga
     3781 aaaagtaatt tttttcaata aataacctta attttttata aaatcgacaa aaaaacgaat
     3841 aattttatta tatttattgt aaataataca atattacgat ataatacaac agaaaaacaa
     3901 atagaaaatg ttcatataat attagtaata cggtctaata gtttctacaa actcacctta
     3961 aatgggtttt ctatgaatag aatgtcaact ctgaatatat gttctattct atctatatga
     4021 atatatattt ttttgtttat atcttaaagt tttttggagg taaaaatggt accaaacact
     4081 aacaatgtac aaccaggtgg aaataattca tcattaagct ttttagacaa aatgtttaaa
     4141 tttagcgaac gtggctctag ccttaaaaca gaagtaatag gtggagttac tacattctta
     4201 acaatggcat acatagtttt cgtaaatcca gcaatattat ctgaagctgg aatggataaa
     4261 gccgccctta taacagttac catactagct acagccattg gtacacttat atttgcgatt
     4321 ttaggaaatg caccatttgc tctagctcct ggtatgggat taaatgcatt tttcacatac
     4381 tctttggtta taggtgcagg aatcccatgg caaacaggtc ttggggtagt ttttctatct
     4441 ggatgtgtct tctttacact cgcagtaaca ggtcttcgaa agacaattgc agacgcaatt
     4501 cctagagaat tggcagtagc atcttcagca ggtataggtc ttttccttgc ttttgttggt
     4561 ttaaaaaata tgggtgttat aatagctaat ccagatacta tagtttcact tgcagatttt
     4621 acaccaacag ttttaatagc cctttttgct cttatcttaa tggcaatact agaatataaa
     4681 aaagttaaag gtggaatatt gataagtata gtagttgcaa caataatatc tgttatattt
     4741 ggatttgtgg agttgccaac agcaataatc tcaacacctc ctagtatagc accagttgct
     4801 tttaaattag atattgtagg tgcattgaaa ttctcattaa ttggacctat attctctttc
     4861 atgtttatag acatgtttga ttcattagca tttcttatta cttgttgtaa acaaatgggt
     4921 cttgaagatg agaatggtga aataaaagat ttaggaagaa tgttatatgc agatgtttct
     4981 tctactttaa taggctcatt cttaggaact agtactgtta caacatttgg agaatctgct
     5041 tctggtattg cagcaggtgc aagaacagga cttgcttcaa tagtaacagc agcattattc
     5101 ttagctacac ttatatttac accattactt ggtatagttc ctacttacgc tgcagctcct
     5161 gcacttgtaa tggttggtgt gtttatgttt gaaagcataa aacagattga ttttgctgat
     5221 agcaaaatag ctgtacctgc ttttgttaca gttttattga tgcctttaac ttatagtata
     5281 agtattggtt tatgctttgg atttatttca tatataataa tgcatgtagt agctaaagaa
     5341 actgataaaa tcagtattac actttggatt ataggtttac ttgcagttgt aaacttagtt
     5401 ctaagttaat atttttaaat agttctaggt caatatttta aattatatag aataaaatct
     5461 tatttatttt aaatttataa atagcaaaat cactttatat gtaaattgat tttgctatta
     5521 actttgtata gaaaatttat tatcataata tatagatata aaaatatata gaaaaggagt
     5581 ggtgtttatg tcacaattac ttataaaaaa tgcatatcta attactatga atgcagatag
     5641 agaggtatat gaaaatggaa gcatacttat tgaaaataat attataaaag aggttggtaa
     5701 gtttgatatt aatattgtag ataaagatgc agagatatat gatgctaaag gaaaaatact
     5761 aatgccaggg ctagtcaata ctcatgttca cttatctcaa caattaggac gtggtcttgc
     5821 agatgatgtt gtacttttaa cttggcttag agaaagaatt tggccatacg aaagtagctt
     5881 caattatgaa gattccttga tttcatctac tgcatgttgt gttgaattga taaaatctgg
     5941 tgtcactaca tttttagaat ctggtggtca atatgtagat gctatggttg aagctgttga
     6001 taaaactgga cttagagcct gtttagctaa atcagttatg gatacaggag atggtcttcc
     6061 tgaggcatgg caaaaaacta ctgatgagga aatcaacact caattagact tattccataa
     6121 gtttaataat acatctaatg agagaattaa aatatggttt gcattaagaa ctatttttaa
     6181 tacaactgaa gaattacttg ttagaactaa agaactagct gataaataca atacaggtat
     6241 acatatgcat attgctgaaa tagctgatga aatttcattt gtaaagcaaa acaatggagt
     6301 tggaacagtt gaataccttg ataaactagg tgtattagga ccaaatcttt tagctgctca
     6361 tacagtttgg cttactcata aggaaattga tttatttaga ttacatgatg taaaagtttc
     6421 tcatgaccca ggttcagcta tgaaagtggt tctagggttt gcatcaattc ctgaaatgtt
     6481 agaaaaagga atacctgttt caattggtac tgatggagct ccttcaaata atagaatgga
     6541 ccttatgagg gacatgtatc ttacatcact aatacataaa ggaagaactt taaacccaac
     6601 tgtcgtacca gctgaagaag tcttagaaat ggctactata aatggagcaa aatgtgcttt
     6661 actagaaaaa gaaattggta gtcttgaagt aggaaaaaaa gctgatatga ttattctaaa
     6721 tccagataca attcattgtt taccaatgca taatccaatt ggaaatatag tttattctat
     6781 gactagtgaa aatgtagact ctactatttg tgatggtaaa tggttgatga aggaaagaaa
     6841 agtattagtt gtagatgaat ctgaattatt aaataaagtt aaaaaacaag cttctaaaat
     6901 aaaagataaa gcagaagtta aaattccatc taaatttaaa attataaaat aacataaatt
     6961 tcaattgttt tgtaaatatg aatatataaa tatatttata tacatcatat atacaaaaca
     7021 attgtttttt tattttatat tcattagcat tgctcataaa atacaccata attccagaaa
     7081 aaataaccaa tcagttaaga ttacatcatc taagcaatat ataaacgtct tagtttataa
     7141 gttttattct actcttatct aaaaccatct ttaaagagtt ttcaactgtt tcaattacat
     7201 ctttataact caagtacaca tttgcgtaga tacaatcttc atataaatta tattcagtta
     7261 ctctacaata cagcagtttt cctccatcta ataaattgct caaaatatag ttttcttttc
     7321 ttgggacata acctatcaca tatccagttt caccaactat tttaatagct ttttcatcat
     7381 atagattatc tttctctcta gttaaatagt atatcttact tttctccaat tctttttcaa
     7441 gatattctct atttctaaac cttgaaccag caacagctat tgaagtcaaa tagatatcct
     7501 taccatgttc atctactttt attttttcaa tatttacaaa ttcttttttt aaattattac
     7561 tttcatataa tactcttctt aattcatcct tcaatataac atttttttct ttttcatacg
     7621 cttctttaac aatttttaat tcttcaagag atagtttctc tctgtatctt tttaagatat
     7681 ttatggattc ttttcttact tcatttatat ttccaaatat tccttttaaa gatatattct
     7741 ttccttcagg atatagtgat ttacttcctt taagcacaat aaaaaataac atatcatcat
     7801 aatattcttg agtcaattta tctttttcta tatctttcat ttttccaatt aaatcatcta
     7861 ttttaaacgt ctcttcaaaa aaatttaata attttaatct agaacttgtc gttccctttt
     7921 tagatatatg ccaatatacc tcaaaatctc taatatctct atttagatat ggcaacaagt
     7981 catcaaaaga taagttcaca tcataaattt ctgacatttt tataatatct tctgtttttc
     8041 cactagcatc tcttaatgct tcaaaatata tatttttcca tttttcactg agcaagatat
     8101 catttatttc tttttcaaat tcaatcttat tgcactctat attttcatct tttaagacgt
     8161 ttatagctat taggaaaatt gaatataaac tttcaaagtt agtcccataa tttactacag
     8221 taggtaaaaa tcgattcact aattctaatt tattacctat atatttaaat tctacactta
     8281 gtaagtaatt gcatataaga cgtgctaaat tatttatctt ttctttatct aaatctcgtt
     8341 tttcaagata ttcattcaaa tctacaattg aaataatata gttcatcaat aatcgttcgt
     8401 actttgtatc cttataacca tcttcaatta gataggaatt tattttagaa tctaaatttt
     8461 ccatattaac aatagcaaat acttttattg aacctgtagc ctttttagat aaattaaata
     8521 aatatgtatt gtaaaattca agttttttaa tagtattact cagataaaat acgtattctc
     8581 cagatttaga aaatgtatct acaacttctc ttaagttttc tacatttaga tatttctcac
     8641 ttaaaactaa ccctagtttt acatactcaa cttttttact cttatatatt aattctttag
     8701 ttaatttata taaccatttc tcatcaataa tcatttcttt taccaaagta tttatctttt
     8761 tcataaaaat ttcgaaataa caaattaaag acttagaatt actatcctcc aataaataaa
     8821 tttcattaga ttcactttta tacatattta aaatttcatc tactagatta tttgcaagct
     8881 ctacttgttc tcttaacggt atactttcat atatacatag gtaattcatt tcaaatgatt
     8941 ctttgtatcc atcataacca ttaaattcct gcaatcgctt aaaaacattc tccaccaaat
     9001 tatcctcctt tacatgatgt aatttatatt gattatacta cttatttcgt caagtttaca
     9061 tttatacgca aaaaaatatt actagaaatt gaaattctag taatatcctt attattaatt
     9121 atgtaaatac cctatcttat aactgtaaat aatatcctta ttaattttaa ttacttttaa
     9181 taaaaatcta tcctagattt agacttctct atgcatatat tatactaata ttagacatca
     9241 taatcataca ctttttcttt ttcatatctc atgtttacaa acaatgcaag taaaattcca
     9301 acaaatgtta ttgccacatt aaacaataca acatattttg gtccattaac tccccctgat
     9361 tttgtaataa tacctgctat atttaaaata acatagtttg ctatactaga tgcaatcata
     9421 actatagatg ttatttttcc tttattagtt ggaaacattt catttgcagt tgacgttgtt
     9481 aactgaagaa cacctcctgc tgctgaataa cctattacaa atccccctaa catacaaata
     9541 gttggagttt gaacaaaata tacaactaat agcataagta aagctattat aggatatata
     9601 actaatattc ttattggttt aatatatttt ttaataagta aagaagttat taatactgca
     9661 catattactc ccattgagta aaaggattga atttttgtag ggtcagccat cccatacaat
     9721 ttacccaatt cctgattaca atttaaccat aatacaaatg tagatgtaca tgtaaatcca
     9781 atacaaacaa gagctatact tgttggtgta aatttcatct tctctgattt aactgttttg
     9841 cctttgttat caataacatt attagctggt ggaaatggta acacagctat caaaatggca
     9901 tctactacaa taagaatcgc tgttactata aaaataactt taaatgatat tgaatttgct
     9961 gcaacaaatc caattataaa aggaagcaaa aattgtgcta aagctattgt aaatttagta
    10021 aacatatttg ctattgttcc taaactagca aatatctcca tacaagaagg agttacacag
    10081 gtatctaaga atgaatttgc tgcccctcca attattgcaa atacatatgc tatataaaaa
    10141 tttggtgaaa atacaattcc aacaaagaaa attgcatgta gaaagtttcc tataagacca
    10201 cttacttttc ttccatactt atctgaaata ggtcctgcaa atggataaga tataagtcta
    10261 cctaatccta gtgcagcaat aacagctaaa acaatactta catccaatgt tccatctgat
    10321 aatgttttag ccccccacat tgatgaaaat tctggtttgt attgtcctaa aattgaaatt
    10381 ccaataccaa gtaaaaaata tgaaaaatac aacgctatgg cagtaggata atatttttta
    10441 ttgttcataa tttttctccc attcttgtta atttattaac atttttgtgt acaataaact
    10501 catccccata atggatttaa agtatagtca gttaaagctt caaatttaac tggactatga
    10561 ggcaaaaccc actatgacaa tttgtaattt attattaaaa atattgaaat acgtatgttt
    10621 tttcattgtt taagatatta ctcttatcta tttaaagcat aattcattaa cttcttctac
    10681 aggcatttct aatccagtat atagattaaa agcttctgct ccttggtata ataacattcc
    10741 taatccacca atagccttac atccattagc ttcagcatct tcaatcattt ttgttttctt
    10801 aggattataa acgacatctg ttactactaa atcttttctt aaaacactag tatcttttat
    10861 atttgtttca ttgtcatagg gcttcatacc aataagagtt gcatttgtca atatatcact
    10921 tgattgtatc tcctcataaa gtttgtttgt atcttctaaa tcatatagat taacaataca
    10981 ttctgataca tcttttttta tattctcaac tgtttgctct gctcttttat aaaaatcatc
    11041 cttaggatta aagatagata tttctcttgc tccatctaaa gcacattgta cttgtatagc
    11101 agttgctgca ccaccagcac ccataattgt aatcttttta cctttaactt ctaccccatt
    11161 ttcttttaaa ttacgaacat agcctattcc atctgttata tgaccaacta actttccatt
    11221 gtcatttaca attgtattac atgctccaat tatacgagct gctggagaaa gttcatccat
    11281 atattctgta acagcagatt tacatggcat agtaacattg gctcctttta tattaaaagt
    11341 ttttattgct aaaagtgcct cttttacctt atctactgtg atatcaaagg ctaaatatct
    11401 ataatctaaa tctaatttct taaaactata attatacatc actggtgatt tagagtgacc
    11461 aaccggtgta cctattaatg caaataatcc tgttctacct gaaatttcca taactataat
    11521 ctcctcccaa tattatcatt ttctttgcaa ataacctatt cagttattta caaagaaaaa
    11581 tttatttatt atttatatat ttaatgctac ttcaaaagct tcttttgttg catctaatgc
    11641 cctacgagct tttactgcat caccaacaat ataagtttct tttacaactt cttttataac
    11701 ttcacttaat gggtcgtaat tacgagaacc catagaaagt actactgaat caaaaccttt
    11761 taaatcatgc tctgtgccat ctgtaagtaa atagtcgaca ccatcatcat aaaatttaga
    11821 aacttttgca ccagtaatgg tatgtatatt ataattttca aaatcattca taaggaattt
    11881 acggtgttct gaaattacat ctgcaccaac ttcttctcta agctcaataa cagtaacctc
    11941 atgttcttgt tctccaagga aggctgccac ttcacatcca accattccac ctccaacaac
    12001 aagtactttt ttcccacaag attttttacc atcaagaagg tctacagcat gaattaatcc
    12061 tgaatcattg attcctggta taggaagtac aagtggagtt gctccagtag ctataataac
    12121 tacatcaggt gatttctcct ttataagttc tactgtagct tctgtattag tacatatttt
    12181 tacaccatat tgattacatt ttgaaatata acttctaact aagttagtaa tatctccttt
    12241 tcctggagga tatgcagcta aacgcatttg cccaccaaga acttcagatt tttcaactaa
    12301 agttacatta tgtcctcttt tagcacatac ccatgctgca agcatacctc caacacctcc
    12361 accaacaaca agaacttctt tgctaatttc agctggctta agctctgctt catgtcctaa
    12421 tataggattt gcaagacagg ctataggttt gccttggaac atatttggta cacatccttg
    12481 taagcatgca atacatggta tcatttcgtc tagttttcca tttttagctt tattaggcat
    12541 ttctgggtca gccaagcttt gtctaccgaa tgctactaaa tcacatcttc cttgtcttac
    12601 cattaactca gcaaactgtg gctctgtata acgtccaact gttattactg gtatactaac
    12661 agcttttttt atttcagtaa ctaattctgc actgaatcca gcatgtaaag tcgtaggagc
    12721 ccacatatat tcatcatgta tatgtatact acgtgaaaca tgaagtccat ctattccaca
    12781 atcttctaga tatgctgcta ttactgaact atcgtgtaca tcaattcctc ctggaacatc
    12841 atcagtactg tttatgcgac ataatattgc tagagaattt cctacttttt tacgtatatt
    12901 ttcaatgata agacgaggta atctcattct attttcaaaa catccaccaa actcatctac
    12961 acgcttattt gttctttgtg atataaaact actaaccaga tatccatgag cgcagtgaac
    13021 ttcaacagca tctgcaccag ctttttgtgc acgtaatgca gcatctccat aagattctat
    13081 aagttcatat atttcttctg ttgttattgc tagtggtgta ttacgaccat ttgatgcagg
    13141 tattgcagaa gcagctttta atggatgtcc tgctactttt tcatttcctt cagaaccagc
    13201 atgttgtaat tgtatagata ccttcgaacc tgcatcatga caagcatcta ttacattttt
    13261 aaaactatct attgtgctat catcatataa acaaggctta cgaggacctc cttttgcttt
    13321 tttgtctaca acactagatt ctatagttat taatccaaaa ccacctaaag cacgctcaag
    13381 ataataagcc ttagaagttt cacttaaagt accatctgtg tttgcaaaat tgtttcccat
    13441 agggggaact acaaaacgat ttggaactgt cattgaacca attcttatag gtgtaaacat
    13501 agaactaatc ttcataaggt tttccttcct ttcaagtttt atattataat actctgtata
    13561 tttttatatt atataagttt attttggaga tacttcagac catgctttat ccaaaacttt
    13621 tttagttgca ttaaatacag tttcagcagc agtggataac cctttagata ttagagaatc
    13681 agatattact tctgccccta tgactcttgg tgatatattg tgttctttta ttattttcac
    13741 aaattcctct gtgtttccat atccttcacc tggagccaaa cggtcatgta gtgattcatc
    13801 cctaagtttt tcataaggag tttctaaaac atcacacact tgaattgata ctatcttatc
    13861 tgctggaaca ggtgcaaggt cctctgctgt ctgctttgct ctagcccagt gccaagtatc
    13921 taatataagc attgcatttt cacgattaca tcctttcaca acacgccatg cagtagccaa
    13981 atctggtaca ccactatatg gcataaactc aagacctata ataagttcac ctgctctgtc
    14041 acataattct cctaatgcag ttataatttg ttcttctggt atcatctcta ataatccaca
    14101 atttatatgt ttaacattaa ataagtgagc catatgataa acattttgct ctttttctct
    14161 ttgagcttcc gttctatctt cttctcttcc ccattgagtt atatattcta cttctgtaac
    14221 tttcatatca tattcattaa gaattgcaat catttcttca tctgtaacac ctgcattttt
    14281 tgcatcaata taattttcag cacgcaatcc aataccatca aacccagctt cttttgcaat
    14341 acgaactcta tcacggaatg aaacttctgt tcccaatgta taagaactaa ttgtaattgg
    14401 aatattaaga tttttttgat tattcatagc ttaaatttac cccctttatt ttctttataa
    14461 ttaatagtat ttttgatttt atatttttat ttatcctact agtagtatta ttttacctta
    14521 aaaataaaag tattttttga tttctattta tctagatttt ataaatttat tgtatcacga
    14581 gactttacta ataacaaatt gataatttcc tattaattca tagattttgt ttatagattt
    14641 tatttataag ataattcttg tatttttcta ttaggtcgta taaatatatt tatcttataa
    14701 ttcagacaaa aaacgataaa tttttttaaa agcttttatt cttactctat aatcatatat
    14761 aataaaaatg taaaaatatc ttaaaggtta acttctacaa atatataaat aaaaatacct
    14821 atgaaaggat gaacaaaaat tgaatttata tcacttacgc tattttgtta cattggcaca
    14881 tttagaacac tatacaaaag cggcagaaaa tttatctata acacaaccaa gcttaagtca
    14941 tgctatttct ttactagaaa atgaactcgg ggtggctcta tttgaaaaag aaggtagaaa
    15001 tatagttctt actaagtatg gaaaaatatt tttaaaagat gtggaaaaat cattagaaat
    15061 tttagattca agtgtaaaat cattaaaaat aactggtact ggtgaaggac aaatagactt
    15121 agcttttctt agaacacttg gtactgattt tatcccagac atagtgcata aatttttaaa
    15181 atctaatcct gctaaatcaa tagattttaa atttcatact ggtgtaacta ctgacattat
    15241 tcaaggtctt agagaaagaa aatatgatat tgcattttgt tcgaaacttg aaaaagaaaa
    15301 gggaattgaa tttatacctg ttgccaaaca agatttagta ctaattgtac catatagtca
    15361 tccactagct gcaaaggata ctatagattt aaaagaaacc ataccttatc ctcaaatagt
    15421 atttaatcag agaagcggtc ttagatatat aattgatgat atgtttaaaa aaataaatca
    15481 acagcctaat atagtctatg aagtagagga agaccaagta attgctggat tagttgcaaa
    15541 aaatttcgga attgctgtag tcccaaatat gaatatgctt agctttacaa aagtaaaagt
    15601 aattcagatt attcacccaa gttgggaaag aaacttttac ttagcattta taaaagatag
    15661 atatttgcct cctgcaatta aaaactttaa aaactttgtc attaaaaacg ctcaattata
    15721 atttattaat aaaggggtta tttttaaata tcctctttta ttctttttat aaaataaaaa
    15781 aatctatact tttaaaagta tagattccta actgacagtc ggcatccgag tctcagtaat
    15841 tatcgttata caacagcaac tggattcagt tcctgaataa ctaggttact tacattatat
    15901 cagatttttt aaaatttgtc aattgtatct aacgcatttt ttcaagccat ggtccaacag
    15961 gctctacaat aggaacttct ttaaatcccc aatttcttat atcattcaca ctcgttggag
    16021 tatatatttt gtttctgaca gatttgaata ttttgttttt ttctccatat tgcatacact
    16081 ttggattagc ttctattaac cctcttcttg ctctgctaag aggattacat aaaatatctg
    16141 ctatttctaa accttctcta tagtcagcat cttctttttt ggcaattata aaacccttaa
    16201 ccttatctct taattcttca tctatatcta agtatattgt tccattatta aatacatcaa
    16261 aaaacgcctt ttgtactttt aagtttgaga catcatccct tgactctata actattcgtg
    16321 cagattctac agtttcatta tttacaaatg aataaaaatt ctgaagaaca tgtataaaag
    16381 ccacaacata cggttccttt gaaggtgcat aatatttctt taatctagct ttatctactg
    16441 ttactgatat tatagtacac tctaatctag atagaaataa aggcaactca tcatagaata
    16501 acttaatctg tgaatcatca aacttctcaa atgctcttga ttttcttgat atatctgtca
    16561 aatgtattcc tatgttactg gttccaaaac aatactcttt aaatgcatcc atttctttcc
    16621 tcaaagaaca tacataatcg ccttgactta ctgcatattt atattcaaaa attactcctg
    16681 tcaatgtaaa tgggtcttca tgatttatat cagctcttcc actttcatca ataaacatta
    16741 tatatttttt ctttataatc ttactcaccc tcttaacata tgatgatagc atctatattc
    16801 attttatatg agttttaaaa atattccaag atttttatat aacttaaact taattttata
    16861 ctaaaaaatt gagatgtaaa acaatcaagc ttttattgat tgaatttcac atctcaatta
    16921 taattatttt tcaatatata tttttactat tttgcaagaa tatccattaa tttatccatt
    16981 actatataag atactccgcc tcctatttga taaggagttt caactttttt atttgcaaat
    17041 actctttgtt gctctgatga taatcctgaa ttatccatta aaactattgg tgaatgtaat
    17101 tttacagcta atggtccagc tgataaagca tctactaaag catctgattt actaactaat
    17161 acagcctgta aatcagtatc tccatagaat ttttctatta ctttggcatt agtatctact
    17221 ctactatctc catatattct atttcctgaa atatcttcag tagttatatc attcattttt
    17281 gctattactg aatcgttaat tgcacttggt ccacctataa agtatgcatt ttctaatttt
    17341 ctttctgtta gccatttata agattcttct gtaattccat ctttattgac taatattata
    17401 ggttgttttt cttccccagc tttagaagct acagataaag catctgcctc cccatttcca
    17461 gaaaccatat atgcagtttt tatttcttct cgatttccaa gttcttcagc tattcttgta
    17521 gcagtttgat atctatcttg acctgctatt ctctttgttt ctgtgttgaa agtagttttt
    17581 atttcttgct ctaatttaga acttattgca ttttctccac ctatcaagat tactgtttta
    17641 ggtgctaata acttcatttc ttcaacagtt tcagttggta aattagctgt attagtaagt
    17701 agtattgttg agtcatagct acttgctaaa ggagttgctg ttataccatc agctattgca
    17761 ttaccattta ctaatattac agtatctgag ctatcagcat tccagtttcc aactgaactt
    17821 atctttttag ctgtatcaaa tctatttgca cctataattg tatcccatgt aggatttata
    17881 gttccatctt cattaaaagt ataatctttc ccatctattt tttgagaacc agttagcatc
    17941 tttccatctt tgtctaaata gtaagactta ccatctattt gttgccatcc tgtctgcatt
    18001 attcctgttt tgtcaaagta atacttatta ccatctattt cttgccatcc tgttactgct
    18061 aaaccatcag atcctagata gtatttcttt ccattctttt cttgccatcc tgtttgcatt
    18121 actccatctg agttaaagta ataagttttt ccgtctatta ctttccatcc agatactctt
    18181 gctccatcag ttcctaaata atattttttg ttattaattg ttttccatcc tgtttgcatt
    18241 actcctgaag catcaaagta atacattttt ccatttactt ttagccaact attcttttgg
    18301 tatgttccat cagattttac ataatacttc ttaccatttt ctgttttcca tcctgtttga
    18361 tttagattta tcttatattt tgccgctatc tttacatagc tgtcgttact ataatctata
    18421 attacatctg aacctacagg aacttggtca aataaccatc taacatcttt attgtgcatt
    18481 cttatacatc caccagaaat atgctttcct atagaactct cattattatt tccatgtatt
    18541 ccatatgtat ctccataagt tccttttaat gctaatccca tccatctatc tcctaatgga
    18601 tttcttggac ttcctccagg tatattacct ttataatatg gtctattttt tatcttgtta
    18661 actacttttg ttttccctgt tggtgtttct gacccctttt tacctgttgc aactctaaat
    18721 tcttttacaa gtttattatt tacaaaatat cctagagtat tttttcttga atttactata
    18781 atcacatgtt tactggctgc gcttgattct ggtacgccac atgcaaatac taaaactaaa
    18841 gtcagtgcta gtactaaata cttttttaga ctttttttca ctataacttc cccctctttt
    18901 agaaacatta ctacatgtgt ctaattataa cataaaatta ccaatacctt atatttacaa
    18961 atttgttaca tttatacata taagtatgta ttctactctt catacccatt aggattcata
    19021 ctttgccatc tccatgaatc ttcacacatc tcttcaagtt catacttagc tttccatcca
    19081 agctcttttt ctgcctttga agaatctgca taacacatgg ctacatctcc agcccttctt
    19141 cctacaatct tatatggtat ttcttttcca cttgctttag aaaatgcttt tactaaatca
    19201 agaacactat acccctttcc agttcctaaa ttataaacaa caagtcctgg attttcttct
    19261 aatttttgta atgcttttac atgaccagca gctaaatcta atacatgtat atagtctcta
    19321 actccagttc catcatgtgt tggatagtca ttaccataaa cactcaattc cttcaattta
    19381 cctactgcta tttttgttat ataaggcatt agattgctcg gaactccatt tggttcttca
    19441 cctattctac cacttttatg agcaccgact ggattaaagt atcttaaaag agctatatcc
    19501 aatgacttat ctgcttttga tatatctact aacatctgct ctatcataag tttagttctt
    19561 ccatatggat tggttacaga aagtgggaaa tcctctaata taggacaagt atgtgggtct
    19621 ccatatacag tagctgaaga actaaataca aactttttaa caccatattc tctcattaat
    19681 tcaaataaat ttaaggtact tattagatta ttgctgtaat attcaattgg tttttctact
    19741 gattcaccaa ctgcttttaa agctgcaaag tgtataattg attcaatatt attttcttta
    19801 aatacaacat gcatttcatc tttatttctg atatcaatat tataaaattt tactggtttt
    19861 ttagataatt ccttgattct atcaaccact attgagttgc tattacttaa gttatcaact
    19921 ataacaactt cataacctga ttctaaaagt tctattgctg tatggcttcc tatatatcct
    19981 gctcctccag ctactaaaac tgccattgta attacctctt ttctaatatt tatttttcac
    20041 ttactttttt tctcatatag tccattaaat catcttttaa attttctctc tttagagcaa
    20101 agtctattgt tgcctctaaa aaaccaatct tatctcccac atcatatctt ctaccttcaa
    20161 agttataagc ataaatagcc tcttgttttc caagagtttg aagtgcatct gtcagttgta
    20221 tctctccacc tttaccaggt gtctgtttct ctaatatgct aaatattgca ggagttatta
    20281 tatatcttcc aagtatagct atatcagatg gagcttcttc aattgcaggt ttttcaacca
    20341 tatctttaac tttatatact ctatcttcga tatgttttac atccaatata ccatatttat
    20401 tagtatcttc tttagctatc ttttgaacac ctaatacagt tgttttatac tcattataag
    20461 tatctattaa ttgttttaag cacggaacat ctgaatctac tatatcatca cctaataata
    20521 cggcaaaagg ttcatcacct ataaaacttt ttgcacagta aattgcatgt ccaagacctt
    20581 ttggctcttt ttgtcttata taatgaatat ttaccatatt tgatatgtct cttaccattt
    20641 ctaacatctc tgtcttacct ttttgctcta gttctaactc taattcaact gatttatcaa
    20701 aatgatcttc tatagatttt ttatttctac ctgttattat aagaatttct tcaattcccg
    20761 attctatagc ttcttctatt atatactgta aagttggttt atctactata ggaagcattt
    20821 ctttgggctg tgattttgtt gctggtaaaa atctagttcc tagccctgct gctggtatta
    20881 ttgctttttt aactgtcatc tgcatttttt cacccttctt cgtaaatttt ctattgtacc
    20941 aaattaatat accatattta tactttttct tcaaactcta tattatccca atatttaatg
    21001 ctataagata atataaggta gatgaaattt catctacctt tagttttata agttaatatt
    21061 gtattgttta tattttatcc aaaacttata caggtactaa atttcatcta agatgccttt
    21121 tatatcacta tctatatctt catctagata agaatctaaa tcttctaagt caacttctag
    21181 ttcttgatat gtcatatcaa cactgacatc ctcatctata tccatttctg atattaattc
    21241 tcctaaaata ctatttccat cagaatctaa accactatct atatcttcat ctatatagtt
    21301 ttcatttaaa atttcatcta aatcaatctc ataataaact tcattatttt tttcatcccc
    21361 tgagtccaat cctaagaact catagttaaa agtccaaaca ttgtatttac ttgacatact
    21421 ttattcctcc tgtgaaaaac atattttcat ctagtttatt ggttccataa tcaacagagt
    21481 tatatatttt ttcaattatg tcttttcttc tttcttttgt actattattt aatgtcaatt
    21541 gtttaaatac atatgtattt gttattctct cgaataatat ttcttttata ctatcatcat
    21601 caatatttct atagtttttc cacaataact caaataactt aaacatttcc ctactagttt
    21661 catctacata ataaggatac atattttcta ctaaatggtt taatcttgat atggcttgtt
    21721 ttaaaaatac atcaagactt gcactttcac tttcttttaa cattctataa ttgtatttct
    21781 tcttatcttc tcctgaaatt acaaagatga tattgtctaa acttttttca acttcattta
    21841 aataactgct tatattatat gataaatcag acaatagatt tttaatctgc ttaaacactt
    21901 gtacatcaag tttagtatta tacttttcaa acaaatctat ttcttgattt tctaatattc
    21961 ttggcatata tgctgacaat aaatctaaat tgtttctttg ttcttgtatt tgcttataaa
    22021 gtgaatttat aacttctatt cttatttcat catttaactc tttttctaaa atcttatcaa
    22081 attcagattt catatagtaa atatttccaa agaaattaaa tattatcata tcattcatag
    22141 ctttagacca attcttatat atcacttcaa tagaattttc tttaagtaga ggttgctttg
    22201 catatataaa tacatcttgc ataagttttt gaaccatact tttacttaag tttaaaagta
    22261 ctttttgatt attaaatttt atttccgttt ctacaaaatt agaattttcg ttttcaagtt
    22321 ctttattaat tacaatgtct tttatatcac tattttttat agatatgatt tctttttgaa
    22381 aagactttag aatagtcaag ctatcgaaat cttcttgaat aaaaaatgga gcatgtttta
    22441 atgtatatcc cactatttca ttttctatat cttttaggtc atctatttgc ataatttctc
    22501 tatttttatc atttatatgt aggttaaata catttttatt atcatataat attatatctt
    22561 ctcctaaatt taacttagaa caattatctt tcgctgactt tacaatagtc ttcttagatt
    22621 tcttatttat aaaaattaat tggtcttgat attttactaa aagcatgttt gtgtttttat
    22681 aatcaaatcc atctatattt cctgatatct tgcagaatac tatttcacaa tctttaggaa
    22741 gatttcctat tttttggtta tctttaactc tctcatttaa atcagatggg actacactat
    22801 ctatattgtt attaaatata gatacagacc ttactataat cccctctctt tccatatgaa
    22861 agtatccctt caatgacact cttttatctt ctaaaatgta tctttctata tcatcaaaat
    22921 ttatttcaaa tctatttttc ccactgataa atataaactt ctcattatct ttattaattc
    22981 cacccatata aaacttattg tcatctaaac ttaatatagt catattatcc tttagataga
    23041 atataaattc tctttgactt ttgcagatta aatcatattc atccaaagtt attttcatag
    23101 tcaaatttgc tgtaacattt ttacttgaat tttcactttt tatgtaaaaa ggcaagttat
    23161 ttccatagac aattatttga gaatcttcta aaactgcctc taatttttct ttattgtctg
    23221 aaaaactata tatatatttt acacctgtat cctcattaac ttcatctgat ttgctgatta
    23281 ttatattccc tagatttgtt atatgaagct ttttatattc ttttgagtat ctacttatgc
    23341 cactaagctc aaacccatct gaaagctcat atatgatttt ttctcctaat ttcaacatac
    23401 cttcaccacc taaacagaat tataagtatt ttataaaggt gaataaaatg tctcaaaaca
    23461 aataatattt tttttaatac tttttattct gagacatagt ttctcctttt ttataatgct
    23521 ctaagcacct tcaactattt cttcataaag tttatctaaa tgtttaacat attcacgata
    23581 tccagatttg ttctttaact cacttcttaa atcttcatat ttttgtttaa gttcttcagc
    23641 actcaaagaa ggagctgatt cttttaattc ttctaactta taatcatagt acttatcata
    23701 catagctata tatgtatcaa tagacttctt agctagttca ttacattttt cttgtgcttc
    23761 tccatattga gaataatcac ctatttttat tttatagtat ccattttctt gaattattgt
    23821 tgaagaaata cctttagcct catattcttt tgctgtttct tttgctgttt tttcaacttt
    23881 aagtgaacct gcataaacag tgtaatatac acctttacca tctttatatg cttccatttc
    23941 ttttgctttc ttttcagctt gtgctttttc ttgagcctct ttttcagctt ttgccttttc
    24001 ttctgcttct tttttctctt tttcagcttg tgcttttttc tcttcttcag ttaatttatt
    24061 gttagcttgt tgttgagttg atgactttgg aatattctct ttatcatttt tcttattgtt
    24121 gcctactgtt ataaaatatc ctacaccaac aataaccact ataactactg ctataatagt
    24181 ttcttttaat ctactcttct tagaaacaac ctcttcatca tctaaagaat cttctttatc
    24241 tgatacataa tttttcattt ctttcttgtt ttctctatat ttgtccttag aagaattttt
    24301 agatttttta ttactatttt ctttcttttt aataggtatt actactgatt tttcattttc
    24361 taatttttct tcttttatct cttttgcttt tttatcttct aagtttttac tttctttttc
    24421 aagcttcgat tcattatttg aagatacttt ttcatctaag ttattattta ttggtttttc
    24481 tatttttaca ttacgttctt cttctatatg ttgacttggt tctttttgtt ttatttcttt
    24541 taattcattt tgctccattt cttctgattt tacttgatga ttttcaactg gtttatctaa
    24601 aattatatca ggagaaatat catttaaatt ctcttcttct tgttcaactt cttcattgtc
    24661 ttttttaata aatccaaata atttagcctt ctttttactc tttttatttt ctggttcaat
    24721 tatatcttct ttattgctgt cgtactcttt atctgtagta tctttatctt ctacaacgtc
    24781 acctatatct tgattattac tatctatttc ttctttaacc ccttcttcag catcatcttc
    24841 tattgaaata ctacttctaa agcaaatatc tttatctgca ttttttatca tgtaaatgta
    24901 ttcttcaata tcgatatctt tatttcttct agttcttttt gatgcaattt catgattttc
    24961 taattcacta tagttatctt ttattagatt ctgtgcttta ttccatgtat cttcactaat
    25021 ttctgtttta tttttaatta catagtccac aaattcctta aaattttcag gaccaaattc
    25081 tccaattata gtcagtctca ttgcaccttc tataaggtct ctatttcttc tctttaaaaa
    25141 ttctaataca accgttgcac aagcaaaatc tttaataatt tctttgccaa aaccatatcc
    25201 ttcaacagaa tgaagttctt ctaatccaca taacttctta tattcattgt gtattgtttg
    25261 agatacactt tcattattta agctatttaa cttatctata aacttcgatt ctatatcatt
    25321 tgattttgat tcatgtttta cttttgaatt tttaatttca tttagtagca tgtcattttc
    25381 tgaattatct ttacctaatt gcaaatcctc aatttcagtt gcttttattt ctactttgtt
    25441 ttgttcgtta ttctcttcca cattattagg taccacatct ttattactag ctaatatttt
    25501 gtttacacag aatataattt ctctttttaa ttctcttttc gcatctgctt gatttttaag
    25561 aaataaatct ccacattctt tcttttctaa acttattttt ctaagagata tattaagaag
    25621 gtctttatat aggtttaaaa ccttataatc cttttctaaa cgtcttcttc tctctgatag
    25681 ttccatttta tcataagcta aaaaactatt taaatcattg gcttttagag agtctaatcc
    25741 ctctttcata gccttattta catactttct acattttgct gtagttaact ctaaatcttt
    25801 ttctaattca tctatttcag gtatgtactt atctactatc catttgccaa taagtggttc
    25861 tgtatttctt gctaatgtct tataaaacaa tatattaaat tttaaaagct ctgcatattt
    25921 tgcttcatta aattctactt tttcaaattt cttttccaaa acaccatcta gcttttcatt
    25981 tattttagac tcttgtttta aaaaacttgc tgtgacattt aaaacagtgt ttcttattat
    26041 attattttca ctcaaaacct tcactcctta aatcaattat tttattgtaa tatttacatt
    26101 gtgcaaagtt gctaatttga ttatgatatc taaataatta tttactaaat ttgctacatc
    26161 ttatatcata tcatattatt tacatcattt tactttttct ttttatatct atcttatatt
    26221 ataccatttt taatatctgt actaacttat attacaatat tcctcaaaat tttaaaagta
    26281 gattagacaa atttacaaat aaaaaaacat cagtttaaac tgatgttttt gactatcgaa
    26341 ataattaagc aagtctataa gcggagttct gtattagata atcatctttc taggcctatt
    26401 gtcaccaata ggctcaagcg acctacctac cggagagtac gagcagcact ctttattcct
    26461 atcttggtct tgctccaggt ggggtttaca tagccaacta gtcgcctagc tgctggtgag
    26521 ctcttacctc gcctttccat ccttaccaca atagtggcgg tttatttctg ttgcactatc
    26581 cttaggatcg ctcccactag gcgttaccta gcaccctgct ctatggagct ccgactttcc
    26641 tcatgtaaga ttacatgcga ttatctggct tacttaatat ttattttact tagttatgtt
    26701 aacacaaatt cttttacatg tcaaagtaat attatactaa aaatttaaat ttattcaaaa
    26761 atagtgtaat atagatatat aaactacatt taactcgagg tgatctattg aaaaaattat
    26821 atagaatagt aattaacatt atactagtat tagtaatact ttacagtgga tttaatatat
    26881 actcaaaact taccaaatac aatcatgata ctaaaatatc ctcagaactt caaaaaaaag
    26941 aatataaaaa agaggattta tcaaagatta acagtgattt taaattttgg ctttctgttg
    27001 agaatacaaa tataaattat ccagttgtac aatctaaaga taattcttac tatcttgaca
    27061 aagattttta taaaaaagat tctatttctg gtacactgtt tatggattat agaaataaat
    27121 ctattgatga caaaaatatc ataatatatg gacataatat gaaaaataaa actatgttca
    27181 acaacctaaa taagtttaaa gatgctgact tctttaaaaa aaataataaa ataaaaataa
    27241 ccttgaatgg aaaagaattt ttatatgatg ttttttctgc ttatattgta gaatctgatt
    27301 atgattatct aaaaacaaat tttaacaatg aatctgatta tcaaaattac ataaatgata
    27361 ttacttctaa atcattgtat aaatctccta ttaaggtaaa tagcaatgat aaaatagtta
    27421 cactttctac atgtacctat gaatttgatg atgccagaat ggtgattcat ggtagattga
    27481 tttaaaactc acagacacag tttaaaacaa taattttaaa ctgtgtcatc ttttatacct
    27541 ataatttgta aattagacca ctaaaagtat ttaatacaaa ataacaaata catcaaacaa
    27601 taaaaaacaa taaaaaaaga ctatgctaaa aacatagtct ttactggagc tggtgatagg
    27661 aatcgaacct acaacctgct gattacaagt cagctgctct accgttgagc cacaccagca
    27721 cacctatttt attgtaaatt agcaaaacta atttttaaaa atta
//
LOCUS       DAEPUT010000052        27346 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.054, whole genome shotgun sequence.
ACCESSION   DAEPUT010000052 DAEPUT010000000
VERSION     DAEPUT010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27346
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.054"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            35..196
                     /locus_tag="KRL22_002383"
     CDS             35..196
                     /locus_tag="KRL22_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272862.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALIAVGLVFNAGGVKDVLL
                     ELFNKIIGA"
     gene            280..810
                     /locus_tag="KRL22_002384"
     CDS             280..810
                     /locus_tag="KRL22_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1272863.1"
                     /translation="MCKILLVRPSKQYADQVMSYKEEMSQNGDSFDGCAGLENVQSFE
                     EWIDFEARLKAKYKDGYVPSEVFLAIRKKDNYVIGMIDFRHPLSDFLFNFGGNIGYSV
                     RPSERQKGYASEMLRLILPICHEFGESKVLLTCDKKNEASQKTIVRNGGVLEKEIPDT
                     VGLSESGIIQRYWISI"
     gene            885..1427
                     /locus_tag="KRL22_002385"
     CDS             885..1427
                     /locus_tag="KRL22_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH1272864.1"
                     /translation="MKGFERKNQLFSLCGLNCGLCPMLLGNHCGGCGNGNQSCKIARC
                     SLEHGMIEYCYECKQYPCEKYQHIDDYDIFITSRRQKADLERAKIIGIEQYNLEQQEK
                     TQILSYLLSNYNDGRRKTFFCVAVNLLELSELQEAMKQIQSNDELTLLPFKAQCLYVV
                     EMFQKIADRRNIKLKLIKKK"
     gene            1531..1827
                     /locus_tag="KRL22_002386"
     CDS             1531..1827
                     /locus_tag="KRL22_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1272865.1"
                     /translation="MNDIFKDMQAKVGCENISDLPSYKRKVWHEMKQLNFADYEEKQL
                     EDFSNYVFGMSCQTLKDVMKQQKGREEQCRKQGCWWKRAEQLAKKQHHTGSTCR"
     gene            1746..2249
                     /locus_tag="KRL22_002387"
     CDS             1746..2249
                     /locus_tag="KRL22_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1272866.1"
                     /translation="MQETRVLVETSGTTGEETTSYWFDLPIDVAEFEEKLGVGAESGD
                     YRIIEKVLPFADEVHEHTSVYQLNELDFMYRQLSSDMQEEYTALLTVYENLEALYICR
                     NVIAVYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFEAYASHLLENRRYLVTEH
                     AVFELPE"
     gene            2267..2770
                     /locus_tag="KRL22_002388"
     CDS             2267..2770
                     /locus_tag="KRL22_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1272867.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQC
                     EEYAIHDTDNFPIEIGEYVSIEELNEMYEMIEELPDYIVECLDEFIGHYGTLEEVMEH
                     KDNIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIATSR
                     GMCEIPY"
     gene            2880..3269
                     /locus_tag="KRL22_002389"
     CDS             2880..3269
                     /locus_tag="KRL22_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1272868.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFFI
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLDKQILNETITAVRSVNYVPD"
     gene            3256..5706
                     /locus_tag="KRL22_002390"
     CDS             3256..5706
                     /locus_tag="KRL22_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1272869.1"
                     /translation="MYPIKYIDNNLVWNKDNEVYAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKRLVTGKLREVAVRKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEELLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIDDFGYLMEHLYGRDGIAYEDYEYQLPKKKYKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQTKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGETTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKSVRSVTQSETRGLLHVIDELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFNEYTTIELLSVAMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            5706..7841
                     /locus_tag="KRL22_002391"
     CDS             5706..7841
                     /locus_tag="KRL22_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009757268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1272870.1"
                     /translation="MKERIQSAFTKKKIFHFLKMALFVVALSLILLSLLGTMAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTQNGFSSTGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNENNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNASDSQSMGRRIFSRP
                     YLYMAHRARRMERRLASAVTAGGVAGAVAGSTVSNARTTRNNSAKDNRGNTYSSMGQR
                     AGSKVGAVLDTKNKVKDKANAMKETVKDMPTQTAYAVYSAKEKAKTSVSDFKRGMVQE
                     QQSRQSGRLEKQEQHKKNIADKRMELQKAQEARQARKTDGSATSGATRPHERPATAPT
                     SKTSKPVKINSAKKRPLSSGVSDVKAPQSAQPVHRQNVEKVPVSEKTRQNFKAERTTK
                     AHIVQQPKKITETTEKNRNAIFTKGQKKK"
     gene            7838..8845
                     /locus_tag="KRL22_002392"
     CDS             7838..8845
                     /locus_tag="KRL22_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH1272871.1"
                     /translation="MKLKHIALIGSLFPILFSIVLFFGVLMSADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYAKEYGISEYVNVLLAIIQVESGGTAKDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGINDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYGKAGISLPRTADLQYDATQHIPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYADLNSSYWKQHLIGAGRVK
                     Q"
     gene            8861..9763
                     /locus_tag="KRL22_002393"
     CDS             8861..9763
                     /locus_tag="KRL22_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1272872.1"
                     /translation="MFKKNKKTTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDMHTVHETETIQLRLTDTNGIENFVKNFAKSYYTWNNSKEAIEARTQAISD
                     YLTKELQDLNVDTIRTDIPTSSAVTDVIVWSIEQLGTDTFSATYEVDQQIKEGEQTTA
                     VKATYTVKVHVDADGDMVIIQNPTLAPAIEKSEYEPKTLETDASVDADTVNDATAFLE
                     TFFNLYPTATEKELAYYVARNVLEPIGKDYLYSELVNPIFIKDGDNVKVKVAVKFLDN
                     QTKATLVSQYELVLHKDSNWKIVG"
     gene            9866..10681
                     /locus_tag="KRL22_002394"
     CDS             9866..10681
                     /locus_tag="KRL22_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBH1272873.1"
                     /translation="MFKIGEFSKLTQVSTRMLRYYDETGLLKPAKIDSLTGYRMYSAE
                     QISTLNRIIYLRDSGFNVAEIALALDCSNDTIIEQLDKKSIEIMDNIQKEQEKLKKIE
                     IAKKELLHGKSELYFNITIKEIPSYCVLSLRKEIPNYYYEGELWKELSAFAKENKINI
                     SDETFSIYHNEEYKEKDVDVELCAIVNKIGKATGDFKFRFTEPVSMMACTMVYGDFSN
                     ISYAYRSFAKWLQENSQYKMKGSSRQIVHRGPWNEKNPENYLTEIQIPLENLL"
     gene            10762..11238
                     /gene="tsaA"
                     /locus_tag="KRL22_002395"
     CDS             10762..11238
                     /gene="tsaA"
                     /locus_tag="KRL22_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HBH1272874.1"
                     /translation="MTTYKVNSIGTIYNNEKGAFIQLEAPYILALRALDGFSHINVLW
                     WFSDFDNTDFRSVLETEQPYKNAPEKMGIFATRSPVRPNPIALSVVEIINIDYMNGMI
                     QIAYIDANDKTPILDIKPYTPSLDRVENPNVPDWCSHWPHSLEESASFAWENEFNF"
     gene            complement(11398..12582)
                     /locus_tag="KRL22_002396"
     CDS             complement(11398..12582)
                     /locus_tag="KRL22_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009461880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBH1272875.1"
                     /translation="MILVGIDIGKKQHTFSIIDKGTGEILSNPSVFNNNQKGFLLLIG
                     KLSSYVKSELLIGMEDTGHYHFALLKYLLERHYTVALINPTTTDLTRKLQGGITKNDP
                     LDSLTICDVIGSNQRKKPYRITKVNRFDLYEQKQLTRHHHNLKEELNIYKNRLQKCID
                     IVFPEFNSLFRSKYGIVYMNVLKTFASAEKIANSDIRIIRKCFEYEGRGKRIPLSAEQ
                     LKTVAKASVGIPSVAEEIQIRHLVCQIEMIEEQLSEIDKKIEEFSLQNNSPILSIPGI
                     SHFSGTSILAELGDICNYTKASQIIKFAGVAPYHYESSQFTAQHTAITKKGSRYLRKT
                     LYQIILPVINHNRVFTAYYNKKLAEGKGHRCAQGHCIRKLLRIIYHLLSTGQTFDPAL
                     LI"
     gene            12889..13440
                     /locus_tag="KRL22_002397"
     CDS             12889..13440
                     /locus_tag="KRL22_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1272876.1"
                     /translation="MSLQDYIIEKPVIDTEHLILRTMDKNDIDDLKEWISDISLYEYW
                     GKRPSKSEKNPEVLFSKPEKATKSFHWRIVHKQDSKVIGEIWIYLIENNRMAKVAFRL
                     SKQYQGNGLMSEALKSIIEFCFSKTELQKIWTDVHILNHASYKTLEKVGFQREGHIRG
                     GKMVNTYCDYYLYGILKSDYITS"
     gene            13707..14618
                     /locus_tag="KRL22_002398"
     CDS             13707..14618
                     /locus_tag="KRL22_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1272877.1"
                     /translation="MYAYENIEMSLNYIEQHLSEKIETEKLAEIACLSTFYYQRLFKK
                     LVKKSVQEYIKLRRLAMVIAELNNSEERILDIALKYGFSDHANFTRAFKEVYHIIPDE
                     YRKNVPMLNTFDKPELSSRYIMIDENVPLIVGNIVLEIQRKTLRTKETYFGFEKTVNI
                     AEQIPAGESTGIDVPGQLWREFHAKKLQTENAIFNNDIELGVSHLASPDKGTFLYFAG
                     GMVSSTDVCPKNMVQHTLPAGEYIVCKIEAESFEELVTTALNQANKYLFETWLPNHNL
                     VTKPFMAEKYYKGNAEINYMEVWIIPV"
     gene            14696..15130
                     /locus_tag="KRL22_002399"
     CDS             14696..15130
                     /locus_tag="KRL22_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH1272878.1"
                     /translation="MINIKDINYVPNISEISVYIENSAFDELYQHMNNEYKAVCKIEY
                     SKDVWARGWNVKFKKSGKSLCVVYPKKNYFTVLVVVGNKEKEDVENLLPRLSEYVQEI
                     YRNTREGNGQRWLMIDLKSKNNVYQDVLRLIEIRYAIKCVKP"
     gene            15195..15434
                     /locus_tag="KRL22_002400"
     CDS             15195..15434
                     /locus_tag="KRL22_002400"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272879.1"
                     /translation="MGNEIFRYLRKYFRGLALWKDLSTIPHNQIQSNKALLKIECNTA
                     LKARTNYMFCAGFFHLIGIWIRQRVYYKNKTIRVP"
     gene            15595..16338
                     /locus_tag="KRL22_002401"
                     /pseudo
     CDS             15595..16338
                     /locus_tag="KRL22_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
     gene            16289..16900
                     /locus_tag="KRL22_002402"
                     /pseudo
     CDS             16289..16900
                     /locus_tag="KRL22_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            17113..17970
                     /locus_tag="KRL22_002403"
     CDS             17113..17970
                     /locus_tag="KRL22_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1272880.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERSSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGVHYLSHGKSPKIKKNYIMEDMLHNVYDATTYGIETFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPAWSHRFMGLIQWGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVASLFNADLSCLENG
                     AIQCPVILITAKGDPLFSFDYTNKVFDLIHVPQKELLALELNRHMIFNEDTDTTINAL
                     EVTLYKYLG"
     gene            18048..18629
                     /locus_tag="KRL22_002404"
     CDS             18048..18629
                     /locus_tag="KRL22_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1272881.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFALHGLKKVTVDDLVAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTIKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEDLGVVFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMIQNLLVNGIIQQVVAE"
     gene            18733..19578
                     /locus_tag="KRL22_002405"
     CDS             18733..19578
                     /locus_tag="KRL22_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272882.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KVLTGLNTRYKGSVKVAGTEIREHTNQFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     EKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNSRLMKDIILAEKKRGKTIIITTHNMFDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIQYTYYDKGEKTGECLLDRTTEDKLLKSLISKNRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            19575..20258
                     /locus_tag="KRL22_002406"
     CDS             19575..20258
                     /locus_tag="KRL22_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272883.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALPEHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKISEYILSKTVALIAISTV
                     IALILGVVSGSNHLLGIAVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIVCFV
                     PPIVGLFVKLPYLFRFFPFTACMNLITGKSVLLSFDMVLVIATLIILYIVARHTVKHM
                     WKSLGGVKL"
     gene            20255..20953
                     /locus_tag="KRL22_002407"
     CDS             20255..20953
                     /locus_tag="KRL22_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272884.1"
                     /translation="MKRILSSTIQVFRQIKSDPMMFAACFTPFVMGALIKFGIPFLER
                     ITDFSLQAYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPVPFLIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLVVALVW
                     YYFLTKRLFRKLAG"
     gene            20965..21876
                     /locus_tag="KRL22_002408"
     CDS             20965..21876
                     /locus_tag="KRL22_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH1272885.1"
                     /translation="MEKGRLLQNKNINKAIQVSKITLIINLSLSLLKFAAGYIGKSSA
                     MLSDAVHSASDVLSTIVVMVGIKISEKQPDREHPYGHERMECVASIILSVALAITGAG
                     IGYSGIKKIFSEQYNTLSAPSGIALTAAVLSIVIKEWMYWFTRSAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASVVICGCILKAALDIFKESINKMVDHS
                     CDNATETKIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELLYSA"
     gene            21928..22068
                     /locus_tag="KRL22_002409"
     CDS             21928..22068
                     /locus_tag="KRL22_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272886.1"
                     /translation="MEQYWWIIIVVVLIVVGLLKIVIMKKYNQRRNSNNRSKDSEDDK
                     MY"
     gene            22359..22985
                     /locus_tag="KRL22_002410"
     CDS             22359..22985
                     /locus_tag="KRL22_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1272887.1"
                     /translation="MSDTKENILKIALHLFAVNGYEAVSVSMIAEALGMTKGALYKHY
                     KNKQDIFDCIVERMYQIDNKRAKDYQVPESTIEVTPNAYRNTTIGSLITFTLAQYDFW
                     VTDEFASNFRKMLILEQYRNLKMNVLYQKCLVNGPISYIEDIFNEMIKKGVLQECDTK
                     QLAIEYYAPLFLLISVADAVENCWDLKTQLTTHVKQFVKKYIINEKVK"
     gene            23107..23823
                     /locus_tag="KRL22_002411"
     CDS             23107..23823
                     /locus_tag="KRL22_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1272888.1"
                     /translation="MEYIRSKKYFTPDLQTKIMGPNPIKLQEELLQNHKIPSGSYVCD
                     LGSGQGLTSVFLAKEYGFVVFAVDLWSEPKENEEFFKKMGLSSAQIKSVKADANELKF
                     EKEFFDAVVSTDSYNYFGRDPIYLDEKLLPFVKKGGFVYITVPGMKKDCHEKLPEELL
                     LSWTPEELDYIHDITYWSNIISHCKKADLISIYEMESNSEVWSDWIKQNNEYAINDRK
                     AIEAGGGDYLNFIAIILQKK"
     gene            23987..24178
                     /locus_tag="KRL22_002412"
     CDS             23987..24178
                     /locus_tag="KRL22_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBH1272889.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            24202..24432
                     /locus_tag="KRL22_002413"
     CDS             24202..24432
                     /locus_tag="KRL22_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272890.1"
                     /translation="MIGLKRRDMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            24699..25118
                     /locus_tag="KRL22_002414"
     CDS             24699..25118
                     /locus_tag="KRL22_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1272891.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELKRRKNKEISFS
                     ELPDITVEGLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKKRNNVLMYYFL
                     EMSDTEIADIMNYTRGAVFKHRHRALETMKEILKEKK"
     gene            25121..25375
                     /locus_tag="KRL22_002415"
     CDS             25121..25375
                     /locus_tag="KRL22_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1272892.1"
                     /translation="MKKKYKHPSYYLISSAMDGDETAIEKLLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGRIREALIKMILDFEIDIDIETEEE"
     gene            25750..25953
                     /locus_tag="KRL22_002416"
     CDS             25750..25953
                     /locus_tag="KRL22_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1272893.1"
                     /translation="MNNTDVPIWEKYTLSIEEASRYFRIGEKKLRKLAEENLDSGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            26031..27221
                     /locus_tag="KRL22_002417"
     CDS             26031..27221
                     /locus_tag="KRL22_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1272894.1"
                     /translation="MSKMKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYAWK
                     LVPTDKTPAGKRDDISLREKEKQIKKDLDDGIDTVGGKMTVCQLYEKKNNQRKNIKRN
                     TKIGRQYLMNALENDPLGMRAIDTVKQSDAKEWAIRMNDKGYSYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFNFKLSDVLEDDMEAKVILTPEQEEKLLAFMETDNVYSKYRDEVI
                     LLLETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISTPKTKNGKRELPLTE
                     RAYQALERILKNRGKAQPLVVDGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHK
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELE
                     KLAS"
BASE COUNT         9133 a         4496 c         5787 g         7930 t
ORIGIN      
        1 atggttttta agtaacgccc agagcttagt gcttatggcg attgtggtta ttggtatcta
       61 cttagggttc aaacgtgagt tttcaaaact tatcggcttc ttggtagttg ccttgattgc
      121 tgtcggtttg gtattcaatg ctggcggtgt gaaagacgta ttgttagagc tgttcaataa
      181 gattatcggt gcgtaaaatt ttattgtggt gctgatatga gaatgctata atgtggatat
      241 gaagaaagcg acaaatggga attttggggg agaagtaaga tgtgtaaaat attgttagtc
      301 agaccgtcta aacaatatgc agaccaagtt atgtcatata aagaagaaat gtcacaaaat
      361 ggagatagtt ttgacggttg tgctggtctt gaaaatgtac aatcatttga ggaatggatt
      421 gattttgaag caagattaaa agcaaaatat aaggacggat atgttccatc agaagtgttt
      481 ttggctatac gaaaaaaaga taactatgtt attggcatga ttgattttcg acacccatta
      541 tccgacttcc tctttaattt tggtggtaat atcggatata gtgttcgtcc atcggaacgg
      601 cagaaaggtt atgcgtccga aatgttaaga ttgattttac ctatctgtca tgagtttggg
      661 gaaagcaaag ttttactaac atgtgataaa aagaatgaag catcacaaaa aacgattgta
      721 agaaatggtg gcgtgttgga aaaagaaatc cctgatacag taggacttag tgaaagtgga
      781 attatccaac gatactggat ttcaatatag actctctttc atcaaatcca gtttgtaaaa
      841 gtcaataaat acaaagataa atttgaagtt aggagactaa tactatgaaa ggatttgaac
      901 gcaaaaacca attattctct ctttgtggat tgaattgtgg gttgtgtcct atgcttttag
      961 gaaatcattg tggcggttgt ggcaatggta atcaatcatg taaaattgca agatgtagtc
     1021 ttgaacatgg aatgattgaa tattgctatg agtgcaaaca atatccgtgt gaaaaatatc
     1081 aacacattga tgattatgat atttttatta cgagcagacg acaaaaagca gatttagaaa
     1141 gagcgaaaat cataggcatt gagcaatata atcttgaaca gcaggaaaaa acacaaattc
     1201 tttcttactt actttctaac tataatgacg ggcgtagaaa gactttcttt tgtgtagcag
     1261 tcaatttatt agaactttca gaattgcaag aagcaatgaa acaaatacaa tcaaatgacg
     1321 aattgacctt actaccattt aaggcacaat gcttgtatgt ggtagagatg tttcagaaga
     1381 ttgccgacag aagaaatata aaactgaaac ttatcaagaa aaagtgattt ttaaatttca
     1441 gtttgacaac ttcatatcca tacacacaaa gcagttagtc ttaagatcga ctgctttttt
     1501 cttactttaa tttcagattg gagtgatgaa atgaacgata tttttaagga tatgcaggca
     1561 aaggttggct gtgaaaacat ttcagacctg ccctcttaca aacgtaaagt gtggcatgaa
     1621 atgaagcaac tgaactttgc tgactatgaa gaaaaacagt tagaagattt ttctaactat
     1681 gtgtttggta tgtcatgcca gaccttaaaa gatgtgatga aacaacagaa aggacgtgag
     1741 gaacaatgca ggaaacaagg gtgctggtgg aaacgagcgg aacaactggc gaagaaacaa
     1801 catcatactg gttcgacctg ccgatagatg ttgccgagtt tgaagaaaag ttaggtgtcg
     1861 gtgcagaaag tggggattac cgcattattg aaaaggtact gccctttgct gatgaagtcc
     1921 acgaacatac aagcgtgtac cagctcaacg aattagattt tatgtaccgc cagctttcaa
     1981 gcgatatgca ggaagaatat acagcacttc ttaccgtata tgagaactta gaagcacttt
     2041 atatttgcag gaacgtgatt gcggtttatc ccgactgcaa aagcatgata gatgttgcaa
     2101 gacaaaagct gatgaacgac ccgacgttca aacatttatc cgaggactgt caagaatact
     2161 actttgactt tgaagcctat gcttctcact tactggaaaa cagacgctat cttgtaacgg
     2221 aacacgctgt ctttgaactg ccagagtaga aaatgaggtg gtacttatga ttgatgatat
     2281 ggcagtttat atcgctaatc ttggcaagta caatgagggc tatttagtcg gtgcttggtt
     2341 cactttccct attgatgagg aagatgtgaa agaaaaaatt ggtttgaatg aacaatgcga
     2401 agaatacgca atccatgata ccgacaactt ccctattgag attggggagt acgtttccat
     2461 tgaagaactc aatgaaatgt atgaaatgat agaggaactt cccgactaca tcgtagagtg
     2521 tttggacgaa tttatcggtc attacgggac gctggaagaa gtcatggaac acaaggacaa
     2581 tatttattat tatcccgact gtgaaaccat gacagacgtt gcctactact acatagacga
     2641 attgcaggca cttggagaca ttccacccag cttgcagaac tatatcgact atgaagccta
     2701 tgggcgagat ttagatatgg gcggttgctt cattgcaaca agccgaggta tgtgcgagat
     2761 accatattaa cgctggaaga tcagcgacaa gtattgttgc tactgacagc gtatttctct
     2821 tttaagggac agtctgaaac atggctgtcc ttttccattt tgaaaggagt tgaaagaact
     2881 tgaaaaagat taaaagctac acgggtatct ggaatgtaga aaaagtctta tatgcaatca
     2941 atgactttaa cctacctttt ccagttacct ttacacagat tacatggttt gtgattacag
     3001 agtttttcat cattctgttt ggggatatgc caccactttc catgattgag ggagcatttt
     3061 taaaatactt cggtattccc gttgctctta cttggtttat gtcccagaaa acgtttgacg
     3121 gaaagaagcc gtacagtttt ttgaaatcac agataaccta tgccctgcga cccaaaatca
     3181 cttatgcagg aaaagccgta aaactggata agcagatatt aaacgaaacg attacggcag
     3241 taaggagtgt gaactatgta cccgattaaa tatatcgaca acaatcttgt ctggaacaag
     3301 gacaatgaag tgtacgccta ctatgagctg ataccttaca attacagctt tctatctgcg
     3361 gaacagaaat ttattgtgca tgacagcttt cgccagctaa ttgcacagtc ccgtgagggt
     3421 aaaatccatg ccttgcagat tgctacagaa agctcaatta gaagtatgca ggaacagtcc
     3481 aaacgattgg ttacggggaa acttcgtgag gtggcggtaa gaaaaattga tgaacagacc
     3541 gaagcgttag tatctatgat tggggacaat caagtggact accgcttttt tcttggcttc
     3601 aagctcatgg taacggaaga actgctcaat ctgaagaaca tcaaaaaatc ggcgtggctg
     3661 acattcaaag agtttctcca tgaagtgaac cacacgctga tgaatgactt tgtttccatg
     3721 ccgaatgatg aaatcaaccg ctacatgaaa atggagaagc tgttggaaaa taaaatctca
     3781 aggcgtttca aagtacgccg attagaaatc gatgattttg gctatctcat ggaacatctc
     3841 tacggcaggg acggtattgc ctatgaagat tatgagtatc agctaccaaa gaagaaatac
     3901 aaaaaagaaa cgctgataaa atactatgac cttatccgtc cgaccagatg tgtgattgag
     3961 gaaagccagc gatacttacg actggaacat gaggacaagg aaagctatgt gtcctacttt
     4021 accgtcaatg cgattgtggg ggaacttgat tttccgtcct ctgaaatctt ttatttccag
     4081 caacagcaat tcacattccc cgttgatacg agcatgaatg tagaaatcgt ggaaaataga
     4141 aaagctctta ccacagtacg caacaagaaa aaggaattga aagaccttga caatcacgcc
     4201 tatcaagcag gaagtgaaac aagctcaaat gtagtggacg cattagacag cgtggacgag
     4261 ctggaaactg atttagacca gaccaaagaa agtatgtata agctaagcta tgttatacgg
     4321 gtgtctgcac ccgatcttga cgagctgaaa cgccgttgtg atgaagtcaa ggacttttac
     4381 gacgacctca atgtaaagct ggtgcgtcct gctggggata tgctggggct tcattctgaa
     4441 tttttacctg ccagcaagcg atatatcaat gactatgtgc agtatgtaaa atcagatttt
     4501 ctagctgggc ttggttttgg tgcgacacag cagttagggg aaactacggg tatctatatg
     4561 ggctattctg ttgatacggg aagaaatgtg tacctgcaac cgtcccttgc cagtcaaggc
     4621 gtaaaaggaa cggttacaaa tgcccttgct tctgcatttg tgggttcgct tggcggtgga
     4681 aagtcgttct gtaacaacct gcttgtgtat tactctgttc tctttggggg acaagcggtt
     4741 atcctagacc cgaaatcaga gcgtggcaac tggaaagaaa cacttccaga gattgcacat
     4801 gaaatcaata tcgtaaacct taccagcgat aaggacaacg caggacttct tgacccgttc
     4861 gtgattatga agaatgtaaa agacgctgaa agtcttgcga ttgatatact gacattcctt
     4921 acgggtattt cttctaggga cggcgaaaaa ttccccgtac ttcgtaagtc ggtgcgttct
     4981 gttacccaga gtgaaacaag gggcttgctt catgtgatag acgaacttag aaaggaagat
     5041 accgcaatct cacgaaatat cgcagaccat atcgacagtt ttacagacta tgactttgca
     5101 catttattat tttcggacgg aacggtggaa aatgctatca gccttgacaa ccagctcaat
     5161 atcattcaag tagcagattt ggtattgcca gataaagata ctacttttaa cgaatacacg
     5221 accattgaat tattatcggt ggcaatgttg attgttatta gtacctttgc ccttgatttt
     5281 atccattcgg acagaagcat ttttaagatt gttgatttgg acgaagcgtg ggcgttcttg
     5341 aacgtggcac aaggcgaaac cttatctaac aagctggtac gtgctgggcg agctatgcag
     5401 gcaggcgttt attttgttac ccagtctgcc tatgatgttt caaaggaaag tttgaaaaat
     5461 aatatcggct taaaattcgc tttccgttct actgacatca acgagataaa gcagacctta
     5521 gaatttttcg gtatcgacaa ggacgacgaa aacaaccaga aacgcttacg agatttggag
     5581 aacggacaat gtttattgca ggacttatac gggcgtgtcg gtgtggtgca gatacaccca
     5641 gtctttgaag aactcttaca tgcctttgat accagaccgc ccgtacagag aaatgaggtg
     5701 gagtgatgaa agaaaggata cagagtgcgt tcacaaaaaa gaagattttc cactttctca
     5761 aaatggctct atttgtcgtg gcactttccc ttatcctgct ttcacttctt gggacgatgg
     5821 ctcatgcaac gggacttgtg gacgatacca taaatgcgga aaatctttac tcaaaatatc
     5881 ctctttccaa ctaccagctt gatttttatg tggataatag ctggtcgtgg ttgccgtgga
     5941 actggctgga cggtatcgga aaatcggtac agtacgggct ttactgtatc actaattttg
     6001 tctggacgat aagcctttac ttatctaatg ccacgggcta tgtggtgcag gaagcctata
     6061 aacttgattt tattaacgat atggcagaca gtatcggaaa aagcatacag acacttgcag
     6121 gcgtaacaca gaacggtttt tcttctacgg gcttctatgt gggcttcctg ctactcatta
     6181 tcttagtggt gggactatat gttgcttaca cggggctgat aaaaagagaa accagcaaag
     6241 cacttcacgc tgttatcaac tttgttgtgg tgtttgtatt gtcggcttca tttattgcct
     6301 atgctcccga ttacatcaaa aagataaatg aattttcatc agacatcagc accgcttctt
     6361 tggacttggg aacaaaaatc atgctcccca attccgacag cgagggcaag gacagcgtgg
     6421 acttgataag ggacagccta ttctctattc aagtggaaca gccgtggcta ctcttacagt
     6481 ttggaaacag caatgcagaa gaaatcggga cagaccgtgt agaagctctt gtatcggcaa
     6541 gcccagagga cgaggacggg aaaaccagag aggaagtcgt aaaaacagaa atcgaggata
     6601 acgagaacaa caatctgacc ataccgcagg tggtaaatcg tttaggtatg gtgttcttcc
     6661 tcttgttttt caacttgggt atcacgatat ttgtattctt gcttacgggc atgatgttat
     6721 ttagccagat actttttatt attttcgcta tgttcctgcc tattagtttc ctgctctcta
     6781 tgataccgag ctatgaaagc atggcaaagc aggcaatcgt gagggtattt aataccataa
     6841 tgacaagggc aggaattacg cttattgtaa cggtggcgtt cagtatttcc agtatgtttt
     6901 ataacatttc cacagactat ccgttcttta tggtggcgtt cttgcagata gtgtgttttg
     6961 ctggtattta tatgaagtta ggtgacttaa tgagtatgtt ctctttaaat gccagcgaca
     7021 gtcaaagcat gggacgaaga attttcagca gaccgtatct ctatatggca catagggcta
     7081 ggcgtatgga aagacggctt gctagtgctg ttaccgctgg cggtgttgct ggtgcggtgg
     7141 ctggtagtac agtttctaat gcacggacaa caaggaacaa ttcagcaaaa gataaccgag
     7201 gcaatacata ttccagcatg ggacaacgtg caggctcaaa ggtgggtgct gtcttagata
     7261 cgaaaaataa agtcaaggac aaagcaaacg ccatgaaaga aacggtcaaa gatatgccga
     7321 cacagaccgc ttatgcggtg tattccgcaa aggaaaaagc aaaaacaagt gtatcggact
     7381 tcaagcgtgg catggtgcag gaacagcagt ccagacagtc gggacgcttg gaaaagcagg
     7441 aacagcataa gaagaatatc gctgataagc gtatggagct tcaaaaagca caagaagcaa
     7501 ggcaggcacg aaagacggac ggatcagcga catcgggagc tacccgtccc catgaacgac
     7561 cagccacagc tccaacttct aaaacaagca agccagtcaa aataaattct gcgaaaaaac
     7621 gtccgctatc ttcgggggtt tctgatgtga aagctccaca atcggcacag ccagtacata
     7681 gacagaatgt agaaaaagtt cccgtatcag agaaaacacg tcagaatttc aaggcagagc
     7741 gtacaacaaa ggcacatatc gtccagcaac caaagaaaat aacggaaaca actgaaaaga
     7801 accgtaacgc aatatttacg aaaggacaga agaaaaaatg aaactgaaac atatcgctct
     7861 tatcggcagt ctgtttccta tcctcttttc catagtcctt ttctttgggg tactgatgag
     7921 tgcggacagc gacgacgaga acagcaactt ttcttcgggc attacgggta tgaatttatc
     7981 cgcagaagtc ttgaaacatc agcctatggt ggaaaagtac gctaaagaat atggtatttc
     8041 tgagtatgtg aatgtgttac tggctatcat tcaagtagaa agtggcggta cggcaaaaga
     8101 tgtcatgcag agttcagaaa gtcttggttt accgccaaac tcgttagata cagaaagctc
     8161 aatcaagcag gggtgtaaat attttgcgtc cctgctttct tcctgcaaaa atcaaggaat
     8221 aaatgatttg aatgtggcga tacagtccta taactatggc ggtggctatg tgggatatgt
     8281 ggcaggaaaa ggaaagaaac atacttttaa ccttgcagag agcttcgccc gtgagaaatc
     8341 gggcggtaaa aaagtaacct acaccaaccc gatagccgtt gcaaagaacg ggggctggcg
     8401 ttatggctat ggaaatatgt tctatgtgga attagtcaat cagtatttaa ctgttccgca
     8461 ggtatcggga gaactggcac aaaaggtaat gaatgaagca ttgaaatatc aagggtggaa
     8521 atatgtttat ggtggtagca atcccaacac ttcctttgac tgttcggggc ttgtgcaatg
     8581 gtgctatggg aaagctggta tttcattacc gagaaccgcc gacttgcagt atgacgcaac
     8641 ccagcatatc ccattatcgc aggcaaaggc tggggacttg gtatttttcc attctaccta
     8701 taacgctggt tcgtatgtta cccatgtggg aatatatgta ggaaataatc agatgtacca
     8761 tgcaggcgac ccgataggat atgcagactt aaatagtagt tactggaaac agcacttaat
     8821 tggtgcagga cgagtaaaac aatagaaagg acttgaaaat atgtttaaga agaataagaa
     8881 aacgacagaa aatgtcaaag aaaagaaagt gcgtaccgtg aaagtgggta cacataagaa
     8941 aactgtgatt gcattgtggg tggtgcttat cgcaagcgtg agttttggcg tgtataagaa
     9001 ttttaccgct attgatatgc acaccgtaca tgaaacagaa accatacaat taagacttac
     9061 tgataccaac gggattgaaa atttcgtgaa gaactttgcg aagtcctatt acacatggaa
     9121 taacagcaaa gaagcgattg aagcaaggac gcaggcaatc agcgattatc tgacaaagga
     9181 attgcaggac ttgaatgttg ataccattag aaccgacata ccgaccagct ctgccgttac
     9241 tgatgtaatt gtatggagta tcgagcagtt gggaacggac actttttctg ctacctatga
     9301 agtagatcag cagataaaag agggagaaca gacaacagca gtcaaggcaa cttatactgt
     9361 aaaagtccat gtagacgctg acggggatat ggtaatcata cagaacccta cccttgcacc
     9421 agcaatcgaa aaatcagagt atgagccaaa gacactagaa acagacgcaa gtgtggacgc
     9481 tgatactgtc aatgacgcta ccgcttttct ggaaacattc tttaatctgt acccgacagc
     9541 aacagaaaaa gagcttgcct actatgtagc tagaaatgtg cttgaaccta tcggcaagga
     9601 ctatctttat tctgaattgg taaaccctat ctttataaag gacggggaca atgtgaaagt
     9661 caaggttgct gtgaaattcc ttgataatca gacaaaggca actttagttt cgcagtatga
     9721 gcttgtgcta cataaggata gtaactggaa aattgtagga taacatggaa atgggcttgt
     9781 atcataatta tggtatgcaa gcccttttta tattgaagta taaattaaca ataattataa
     9841 ttaggtacat gaatggaggg ataaaatgtt caaaattggt gagttttcaa aattgacaca
     9901 agtttctact cgtatgttgc gttattatga tgaaacaggt ttattaaaac ctgctaaaat
     9961 tgattcatta actggatatc gtatgtattc agcagaacaa atctcaactt taaatagaat
    10021 tatatattta cgtgatagtg gtttcaatgt cgctgaaatt gcattagccc tcgattgcag
    10081 taatgatacc attatagaac agcttgataa aaagtctatt gaaattatgg ataatataca
    10141 aaaagaacaa gaaaaactaa agaaaattga gattgctaaa aaagaattgt tgcatggcaa
    10201 aagtgaattg tattttaaca taaccataaa agagataccg agttattgcg ttttatcttt
    10261 aagaaaagaa ataccaaatt attattatga gggcgaactc tggaaagaac tctctgcttt
    10321 tgctaaagaa aataaaataa atatttctga tgaaacattc tcaatatatc acaatgaaga
    10381 atataaagaa aaagatgttg atgtagaatt atgtgccatt gtaaataaaa taggaaaagc
    10441 tacaggagat tttaagtttc gttttaccga accagtttct atgatggctt gtactatggt
    10501 atatggagat ttttctaata tttcttatgc ttatcgttca tttgcaaaat ggcttcaaga
    10561 aaacagtcaa tataagatga aaggttcaag ccgtcaaata gttcatcgtg gaccgtggaa
    10621 cgagaaaaat ccagagaact atctaacaga aatccaaatt cctttagaaa atctcttgta
    10681 aaaaatgata atctgccttg actttaacat ggtgttaagg tttatcgttt atttatcaag
    10741 aagaaaacgg aggaaaatat aatgacaact tataaagtaa attcaatagg tactatctac
    10801 aacaatgaaa aaggtgcttt cattcaacta gaagcaccat atattctagc attaagggca
    10861 ttagacggat tcagtcatat aaatgtttta tggtggttca gtgattttga taatacggat
    10921 tttagaagtg tattggaaac agaacagcct tataaaaatg ctccagagaa aatggggatt
    10981 tttgcaacaa ggtcgccagt acgtccaaat ccgattgctt tatcagtagt agaaattatc
    11041 aatatcgatt atatgaatgg aatgatacaa attgcttaca ttgatgctaa tgacaaaacg
    11101 cctatcttgg atattaaacc atacacaccg agtttggata gggtggaaaa tccaaatgtt
    11161 ccagattggt gtagtcattg gcctcatagt ttagaagaat ccgcttcttt tgcatgggaa
    11221 aacgaattta atttttaagg agctaactat ataaaaatca agtggttttt tataaaaata
    11281 gaaatttagt tagtaaaagt atgtaccttg aaaatatgtg aataattatg gattttgtgg
    11341 cacaacaaat agacctttca aagaaggctc gttgtatcag ttggggtgta tttatggcta
    11401 tatcagtaac gcaggatcaa aggtctgtcc ggtacttaaa agatgataga tgattcttaa
    11461 gagttttctg atacagtgcc cctgagcaca tctgtgacct ttgccttcgg ctaacttttt
    11521 gttgtaataa gcagtaaaga ctctgttgtg attgataacc ggcaaaataa tctgatacag
    11581 cgtttttctg agataccggg aacctttctt ggttattgca gtatgttggg cggtaaactg
    11641 gctggattca tagtgatatg gggcaacacc tgcaaatttg attatctgag acgcctttgt
    11701 atagttgcaa atatctccta attccgctaa aatggaagta ccagagaagt gtgaaattcc
    11761 tggtatggag aggataggag agttgttttg caaggagaac tcttctatct ttttgtctat
    11821 ttcagaaagt tgttcttcta tcatttcaat ttgacataca aggtgtctaa tctgaatttc
    11881 ttcagcaaca gaaggtatgc cgacagaagc tttggctact gttttgagct gctcggcaga
    11941 aagtgggatt cgttttccac gcccctcata ttcaaaacat ttccgaatga ttcgaatatc
    12001 ggagtttgca atcttttcag cagaagcaaa tgttttcaaa acattcatgt aaacaatgcc
    12061 atactttgaa cgaaataagg aattaaattc aggaaatacg atatcaatgc atttctgaag
    12121 ccggtttttg tagatgttta attcctcttt caggttgtga tgatggcgtg tcagctgctt
    12181 ttgttcataa aggtcgaaac ggtttacttt tgtaatgcga taaggctttt tacgctgatt
    12241 agagccgatg acatcacaaa tagtaagaga atcaagagga tcgtttttcg taatgccgcc
    12301 ctgaagtttt ctggtaaggt cagtagttgt tgggttgatc agagcaaccg tatagtgacg
    12361 ttcaagaaga tatttgagta aggcaaagtg ataatgtccg gtatcttcca tgccaataag
    12421 aagttctgat ttgacatagc tgcttagttt tccgatgagt aacaggaatc ctttttgatt
    12481 gttattaaaa acagaaggat ttgatagtat ttctccagtt cctttgtcaa tgatggagaa
    12541 agtgtgttgt tttttaccga tgtcaattcc gactaaaatc atgataatac attcctttcg
    12601 taaaaaatat gtaatgtgtt atccacagca cttacttcgt aaaacctggt acgagatacg
    12661 aattcaagac tcatctaact aatcattatt tagaaataag gtgtggtgag aacctcctta
    12721 aagtagtcag agccacagga tgaaaatgta caaatccaca tcacatattt atatgttaca
    12781 aatgtacaac accgtaatca accacggatc aaaaggttga tagaaaggag aaggtatatc
    12841 tgtaaatgac tattagatga gtcaattaca atataccagt gatgaaccat gagtttgcag
    12901 gattacatta ttgaaaaacc agtaattgat acagaacacc ttattttaag aacaatggat
    12961 aaaaatgaca tagatgattt gaaagaatgg attagtgata tttctttata cgagtattgg
    13021 gggaaacgtc cttcaaaaag cgaaaaaaat ccagaagtac tctttagtaa gccagaaaaa
    13081 gctactaaaa gttttcattg gagaattgtc cataaacaag atagcaaagt gattggtgaa
    13141 atatggatat accttattga aaataataga atggcaaaag tggctttcag actttctaag
    13201 caatatcaag gtaatggact aatgagtgaa gcgttgaaaa gcataattga attttgtttt
    13261 tcaaaaacag aattacaaaa aatatggaca gatgtgcata ttttaaatca tgcttcttac
    13321 aagacattgg agaaagtcgg ttttcaaagg gaaggacata ttcgaggggg aaaaatggta
    13381 aatacctatt gcgactacta cctatatgga attttaaaat ctgattatat cactagctga
    13441 tgttatggct aatattgaag cgacgattgg cgaagcaatg aacaatacag ttccaaaggt
    13501 ctatgatacg aaaagcatta aaagatatgt gatgaattta ttagatatgg ctcattaaaa
    13561 agtaccaaag aaataaaagt taccatatag acaaaattgg ttttttatat cttttgattt
    13621 cttataagat aatggcattg tgcgacaagc tatacaaaaa attttcatgt atactttgat
    13681 tataaattat acaaggaggt actgatatgt acgcatatga aaatattgaa atgtcattaa
    13741 actatattga acaacattta agtgagaaaa tcgaaacaga gaaactggcg gaaattgcct
    13801 gtctttctac attttattac caacgcttgt ttaaaaagtt agttaagaaa tcagttcaag
    13861 agtatatcaa acttcgccgt ttagcaatgg taatagcaga attgaataat tcagaggaaa
    13921 gaatattaga catagcttta aaatatggat tttcagacca tgctaacttc acaagagcat
    13981 ttaaagaagt ttaccatatt attcccgatg aatacagaaa gaatgttcct atgttaaata
    14041 catttgacaa gccagaactt tcttcacgtt atatcatgat tgatgaaaat gtcccattaa
    14101 ttgtaggaaa tattgttttg gaaattcaaa gaaaaacatt aagaacaaag gaaacatatt
    14161 ttggttttga aaaaacagta aatattgctg aacaaattcc tgctggagaa agtacaggaa
    14221 ttgatgttcc aggtcagcta tggcgcgaat tccatgcaaa gaaactgcaa accgaaaatg
    14281 ccatttttaa caatgatatt gaacttggtg tatctcactt agcaagtcca gataaaggaa
    14341 cattccttta ctttgcagga ggtatggttt catcaacaga tgtatgtcct aaaaatatgg
    14401 tacaacatac attaccagca ggtgagtata ttgtatgcaa aattgaggca gaatcttttg
    14461 aagaacttgt tactactgct ttaaatcaag caaataagta tctgtttgaa acttggcttc
    14521 caaatcataa tttggttaca aagccattca tggcagaaaa atattacaaa ggaaatgcag
    14581 agattaatta tatggaagta tggataattc ctgtgtaaac agtaaatgct aaataggaat
    14641 tatctgacgt aataaaaagg aaatagaaag cttataaagg agggcatagt ccgttgtgat
    14701 aaacataaaa gatataaatt atgtacctaa tattagtgaa ataagcgttt atattgaaaa
    14761 ctctgcattt gatgagttgt atcagcatat gaacaatgaa tataaagcag tttgcaaaat
    14821 cgaatacagt aaagatgtct gggcacgagg ttggaacgta aagtttaaaa aatctgggaa
    14881 atcattgtgt gttgtctatc cgaagaagaa ctactttact gtattggtgg ttgtaggtaa
    14941 taaagagaaa gaagatgttg aaaacttgtt acctaggctt tctgaatatg tacaggaaat
    15001 ttatcgtaac actagagagg gaaatggaca aaggtggctt atgatagact taaaatctaa
    15061 aaataatgta tatcaagatg tattaaggct tattgaaatt cgttatgcca taaaatgtgt
    15121 aaaaccgtaa taaaaatatt tttcacatac gtaatctcaa ggtattatcg ttgagacaag
    15181 taacctatat aattatggga aatgagattt ttagatactt aagaaagtac tttagggggc
    15241 ttgcgttatg gaaagattta agtacaattc cacacaatca aatacaatct aataaagctt
    15301 tactaaaaat tgaatgcaat acagctttaa aggctcgtac aaactatatg ttttgtgcgg
    15361 gcttttttca tttaatagga atttggattc gtcagagagt atattataaa aataaaacga
    15421 taagggtacc ttaaaaataa ggtacctcag gctgtagaca aagtcccgga ctctcgtctg
    15481 ggcttttctt atatttgagt tatccacaat tcaacttttt aagaattatc ttattaagaa
    15541 aaaagtgtat gttttccacc cgatagtttt acttctgtga tatttgcaga tgccattcaa
    15601 gtagaaagtg gtggtacggc agaagatgtc atgcagagtt cagaaagtct gggactaccg
    15661 cccaactctt tagatacgga aagctcaatc aagcaggggt gtaagtattt tgcgtccctg
    15721 ctttcttcct gcaaaaatca aggtatcgac gatttgaatg tagcgataca atcttacaat
    15781 tatggcgggg gttatgtggg ctatgtggca ggaaaaggaa agaaacatac ttttaacctt
    15841 gcagagagct tcgcccgtga gaaatcgggc ggtaaaaaag taacctacac caacccgata
    15901 gccgttgcaa agaacggggg ctggcgttat ggctatggaa atatgttcta tgtggaatta
    15961 gtcaatcagt atttaactgt tccgcaggtg tcgggggaac tggcacaaaa ggtaatgaat
    16021 gaagcgttga agtatcaagg gtggaaatat gtgtttgggg gaagcaatcc caacacttcc
    16081 tttgattgta gcggacttgt gcaatggtgc tatggaaaag ctggtatcta cttaccgaga
    16141 acggcacaaa cacagtatga cgcaacccag catatccctt tatcgcaggc aaaagctggg
    16201 gagttggtct ttttccattc aacctataac gctggttcgt atgtaacgca cgtcggtatc
    16261 tatgtgggaa ataatcagat gtaccatgca ggcaatcagc ggttatctaa caaagaaatt
    16321 gcaggactta aatgttgata ctattagaac cgttatactg actagcccca cagttacaga
    16381 tgtgattgtg tggaatatcg aacagtcggg aacgaacact ttttctgcta cgtacgaagt
    16441 agatcagcag ataaaagagg gagaacagac aacaacagtc aaggcaacct atacggtaaa
    16501 agtccatgta gacgctgaca gggatatggt aattattcag aaccctaccc ttgcaccagc
    16561 aatcgaaaaa tcagactatg aaccaaggac accagaagca gacggtaaac tggacgctga
    16621 taccgtaaat gacgcaacca catttctgga aacattcttt aatctgtacc cgacagcaac
    16681 agaaaaagag cttgcctact atgtagctag aaatgtgctt gaacctatcg gcaaggacta
    16741 tctttattct gaattggtaa accctatctt tataaaggac ggggacaatg tgaaagtcaa
    16801 ggttgctgtg aaattccttg ataatcagac aaaggcaact ttagtttcgc agtatgagct
    16861 tgtactatat aaggatagta actggaagat tattatgtaa gacattttgt tggcaggctc
    16921 tattttcgga tatagtctgc cttttctgta gcaaatgtac tgcactgaca agctatttca
    16981 ttgtatttta agcaatggaa tctttcttga caattttacc ttaaatcata tatttatagc
    17041 tattgacttt ctgcttgcaa taagctataa tatgactatg aaatcaaatc agtcatatag
    17101 gaggtatggt gtatgtataa agaagttggc atttcttcaa ataatgttcc gataacactt
    17161 tctatttggt atacagaaag aagtagtcct accattgttt ttttgccagg tactatgtca
    17221 caccctctca tgtatgagaa ttttctatgt ggattgagcg aaagagggtt taatataata
    17281 ggtgttcact atctttcaca cggaaaaagc cctaaaatca aaaaaaatta tataatggaa
    17341 gatatgttgc ataatgtata tgacgcaaca acttacggaa tagaaacttt cggtgaaaac
    17401 atagctgtca tgggttccag tcaaggcggg attttagctg caatggcggc aggtagggac
    17461 acaaggttaa aagccgtttt tccacataat atcatgctga ctacattaaa agaaactatg
    17521 agcttaacaa aatatcccgc atggtcgcac cgttttatgg ggctgataca gtgggggttt
    17581 cgtgtaggtg gaaaattgct gcctaactac aaggttccag gagacgctta tttagactat
    17641 gacagagtat tttatagtga acaggcaaaa caagattgct taaatgaccc tatgctttta
    17701 ccctattatc ctttaagatt tgtcgccagc ttatttaatg ctgacttatc gtgcctggag
    17761 aatggggcta tacaatgtcc tgttatttta attactgcca aaggtgaccc gctttttagc
    17821 tttgattata ccaacaaagt atttgattta attcatgtac cgcaaaagga attacttgct
    17881 ttagagctta atcgtcacat gatttttaat gaggacacgg acactacaat aaacgcattg
    17941 gaagttacct tgtataaata tcttggatag catattgatt atataatcag taaatgttat
    18001 acttttcatg acgatataaa tattttagtc ataaggaggt tatgagtttg ccacgattta
    18061 cggaacaaga aaaagaaatc ataaacagta aacttttgat agagggagaa aagctgtttg
    18121 cattacacgg cttaaaaaaa gtaacagttg atgatttagt agctgctgta aacatatcaa
    18181 aaggttcttt ctatgctttt tatcccagta aagaacatct atatgttgaa atcaattttc
    18241 gcttacaaaa agagttattt acaagtatag aaacaaccat taaaaagaaa aagtataaga
    18301 accatagaga tttagcaaag gacgttatca tgctaagttt aacgggggtg attacttcgc
    18361 ctattctttc acagattgat ttatctttaa tggactatct gcaaagaaaa atatcgtcag
    18421 atatttttga aaatcatatg tacagtgata ttcgtatatt ggagatattg gaagatttag
    18481 gggttgtatt tttggttccg catacggtta ttataaaatc cctgtattct gtcttatcct
    18541 gtttggaaca attcaaagag gacgaagaac tgaatatgat acaaaatctt ttagtgaatg
    18601 gtattattca gcaagtagta gcagagtaac aattttgttt ggttatttga caggcaggta
    18661 gccaaacaaa ttttttacag tttatatgac tatatatcta taaacgtcat aaagttaaag
    18721 gaggaatgaa taatgattga tgtaaaaaaa ctgtatttta gctatactga caaaccgttt
    18781 gtggagaatg taagtttcca tgttgggaga ggagaaattt ttggtttttt aggaccctct
    18841 ggtgctggaa aatcaactat tcaaaaagtt ttaactgggc ttaatacaag atataaaggc
    18901 agcgtaaaag ttgcaggtac agaaataagg gagcatacaa atcagtttta tgaaaatatt
    18961 ggggtagact ttgaattttc aacctgctac gagaaattca cagcacgaca aaatctcgcc
    19021 tattttgctt ctctatatga aaagcaacct cggtctattg atgaattatt gcatatggta
    19081 ggcttggaaa atgacgggga caaaaaagtt gctgactttt ccaaaggtat gcgttctcgc
    19141 ttgaatttca ttaaagcgtt agtccatgac cctgatatat tattccttga tgaacctaca
    19201 agcggtcttg accctacaaa tagtcgttta atgaaagata ttattcttgc ggaaaagaaa
    19261 cgcggaaaaa cgattatcat tactactcac aatatgtttg acgcaacaga gctatgtgac
    19321 caagtagcct ttatcgttgc cggaaaagtc agtgcattgg atagcccgca taatttgatt
    19381 atgtcaaggg gagctgccaa aatacaatat acctactatg ataaaggcga gaaaaccgga
    19441 gaatgtctgc ttgatagaac cacagaagat aagttgttaa aaagtttaat ttccaaaaac
    19501 cgtttgcttt ctattcatag tagtgagcct acattaaatg atatttttgt tgatattaca
    19561 gggaggacac ttcaatgaga ttgggacgtt taatttgtgg tgatatacat ttccaatgga
    19621 aatatggttt ctattttatc tactttatat taacagtttt atatgtgtgc gggattgccg
    19681 ctttgccgga acattggaaa acggatattg cttctattat gatctactct gacccagcag
    19741 caatgggatt gtttttcatg ggagcgattg ttcttttgga aaaaagtcaa aaggtattaa
    19801 atgctatggt ggtatcccct gtaaaaatat cggaatatat actttcaaaa acagttgcgt
    19861 tgattgctat ttctacggta atcgcattga tattaggggt agtttccggc agcaatcatt
    19921 tactgggtat cgcagttggt acggctttga cctcagcaat ctttactatg cttggaatta
    19981 ttgcagctac aaaaatttca aacttgaacc aatttctcat tgtgattatg ccgatagaaa
    20041 ttgtttgctt tgtaccacct attgttggtc tgtttgtgaa gttaccatat ctgttccgct
    20101 tttttccatt cacagcttgc atgaacctta taactggaaa aagcgtttta ctatcgtttg
    20161 atatggtact tgtaattgct acgttgatta tcctctacat agttgcgcga catacagtta
    20221 agcatatgtg gaaaagttta ggaggtgtaa agctatgaaa aggatattat ccagtaccat
    20281 acaggtattt agacaaatca agagcgaccc tatgatgttt gcagcttgtt ttacgccttt
    20341 tgtcatggga gctttgatta aattcggtat tccctttctt gaaagaataa cagatttttc
    20401 tttgcaagcg tattatccga tctttgattt attactttct atcatggctc ctgtattgct
    20461 ctgctttgca tttgcaatga ttacattaga agaaattgac gataaagtgt cacggtactt
    20521 ttcgattacc cctcttggta agtcggggta tctttttaca agattgggag taccctcaat
    20581 tatttcggcg gtaatcgctt ttattgtact gttgcttttt tcattagaaa agttgtccat
    20641 tggaatgaca atatgtttgg cgcttctcgg ctcagtacag gcaattattg tttcacttat
    20701 gattattaca ttatcaagca ataaattaga gggtatggca gttacaaaac tagctgcact
    20761 tacattactc ggaatacctg tccccttcct tattgatagt tactaccagt tcgcggttgg
    20821 cttccttcca tcattttggg tagcgaaagc catgcagaat gaagcggttc tttatttctc
    20881 cataggattg gtggtagctt tagtctggta ctacttcctt acaaaacgtc tgtttcggaa
    20941 gctggcagga taaggaggcg tattatggaa aagggtagac ttctgcaaaa caaaaatata
    21001 aataaggcta ttcaggtttc caaaatcaca ctaatcatca acctgagttt atcgctactt
    21061 aaatttgctg ccggatatat aggaaagtca agtgccatgc tgtcggacgc tgtacactcg
    21121 gcttctgatg tattaagcac aatcgttgtg atggttggaa ttaaaatatc agaaaaacag
    21181 cctgatagag aacatcctta tgggcatgaa cgtatggaat gtgtggcttc cattattctt
    21241 tctgtcgcat tggctataac aggtgctgga attggatatt caggtatcaa gaaaatcttt
    21301 tcagaacagt acaatacgct ttctgctcct agtggaatcg cacttacggc ggcagtctta
    21361 tccattgtta taaaagagtg gatgtactgg tttacaagaa gtgctgcaaa gcatacaaat
    21421 tctgacgcac ttatggctga cgcatggcac caccgctctg atgcactctc gtcggttggt
    21481 tccttaattg gcattttagg agcacgttta ggctatgcta ttctcgaccc tattgcaagc
    21541 gttgtgattt gcggttgtat cttaaaagct gctttggaca ttttcaaaga aagcattaac
    21601 aaaatggtag accatagttg tgacaatgct actgaaacaa agattaggga agttgtgctt
    21661 cagcagcaag gggttgatgg tattgatgaa ttaaaaaccc gcatgtttgg agcgaaaatg
    21721 tatgtagata ttgaaatatt agctgatggt aatttagctc tttatgacgc tcatagaatt
    21781 gctgagggag tccatcaaac gattgaaaac aactttccac aatgtaagca ttgtatggta
    21841 catgttaata cgaatgaact tctctattct gcataggaca gggaagatga tttaaggcta
    21901 ttgaaaggga aaggagggaa gtaggttatg gaacaatact ggtggattat cattgttgtg
    21961 gttttgattg tcgttggctt acttaaaatt gtaattatga agaagtataa ccaaaggaga
    22021 aattctaaca atcgttcaaa agatagcgag gacgacaaga tgtattaagg tttattgaaa
    22081 tctgttatgt tgtagaatga tgtttttaga tactagaaag tgctttaagg ggggctaacg
    22141 ttaaggaaag ctttgagtac aattctttac aatcaacagt cttttgcata gagaaatgta
    22201 tgtaggaaat atggtgcaag gcacaaaaca ccagcaattg agaaatcaac ctatgaacca
    22261 aaggcacact acattttata ctacttgaca agtaaacgaa cgtttactat aatggtttaa
    22321 agaagtaaac gttcgtttac taaagaagga ggttgtaaat gtctgacaca aaagaaaata
    22381 tattaaaaat tgcactacac ttatttgcag tgaatggtta tgaggctgtt tctgttagta
    22441 tgattgcgga agccttggga atgacaaaag gagcattata taaacattat aaaaataagc
    22501 aagatatttt tgactgtatc gtagaacgta tgtatcaaat tgataataag cgagctaagg
    22561 attatcaagt accagaaagc acaatagagg taaccccaaa tgcatacaga aatacaacta
    22621 ttggaagtct aataacattt actcttgcac aatacgattt ttgggtgact gatgaatttg
    22681 cgtctaattt tcgcaaaatg ttaatactag agcaatatag aaatttaaaa atgaatgtgc
    22741 tttatcaaaa atgtcttgta aatggtccta tcagttatat agaagatata tttaatgaaa
    22801 tgattaaaaa aggtgttctt caagagtgtg atacaaaaca gcttgctatt gaatattatg
    22861 cgccattatt tctattgata agtgtagcag acgcagttga aaattgttgg gatttaaaaa
    22921 ctcaattaac tacacacgtt aaacaatttg tcaagaaata tattataaat gagaaagtaa
    22981 aataatcctt tattctgtcc taaatataaa cctaactttt taatttcagc agagaaactc
    23041 aaaatgaata ttgttataag tcacaaatat taactattaa aatattacaa taacggagat
    23101 gagaaaatgg aatatattcg cagtaaaaaa tattttacac ccgacttaca gacaaaaatt
    23161 atggggccga atcctataaa attacaagag gaactattac aaaatcataa aatcccgtct
    23221 ggtagctatg tctgtgacct tggaagtgga caaggtttaa cttctgtatt tcttgcaaaa
    23281 gaatatggat ttgttgtttt tgcagttgac ttatggagtg agccaaaaga aaatgaagaa
    23341 tttttcaaaa aaatgggatt atcttctgca caaattaaat ctgtaaaagc tgacgccaat
    23401 gaacttaaat ttgagaaaga gttttttgat gctgtagtaa gtacagattc atataattat
    23461 tttggacgtg accctatata tttagatgaa aaattgcttc catttgttaa gaaaggtggg
    23521 tttgtttata tcacagttcc tggcatgaag aaagattgcc atgagaaact tccagaagag
    23581 ttattgttat catggacacc agaagaactt gattatatac atgatataac atattggtct
    23641 aacataatta gtcattgtaa aaaggcagat ttaatttcaa tatatgaaat ggaaagtaat
    23701 tcggaagttt ggtcggattg gataaagcaa aataatgaat atgcaataaa tgaccgtaag
    23761 gcaatagaag ctggcggtgg agattatctg aattttattg ctataattct acaaaaaaaa
    23821 taaattcttt agaaccaaac actataattt gcgttctaat atgtttaccg attgacatca
    23881 ataattttat ctttgagggt aatgatttga aaatagaaga ataattccag tttgtaaaag
    23941 tcaataaatc caaagataaa tttgtatttg aaaggagttt tgaagaatga aaaaatatga
    24001 gtatgtagaa attaactata atgcgaaagg agttgtattc ctttgtactg ataaacacaa
    24061 agaaattatt gacagttacg caaaaacggg gtatcactac gcagggtttg tacccacaga
    24121 aattgacgca aaaggctgta tgcgaaagat agatttaatt tttgaaaaag aagattaact
    24181 tattttaggg agttggttct aatgatagga cttaaaagac gagatatgaa ttatattatg
    24241 aaagttggtg ctaaagctca aggtgtttct gtatctgaat ttagggctat gctacaagat
    24301 accatagaca aaactatgga aagtacagac ccagacgtgc aggcaaattt taaacgatac
    24361 tttggaaata agcgcccaac accagaggaa tatatttata cgattaccaa aaagacaaag
    24421 gttaaggttt aaatgttgta aagggggctt gccgtatgaa acgctttatg tacaattcag
    24481 tatattcaag cccaatttaa cagcatacta tttacaatta aatacgctat accagtagct
    24541 cgtacaaaat ttatattttg tgcgggcttt tttaataccc gaaaagtttt tttaattatt
    24601 ttcatttttt tggaagcaaa tcacaccttg ctgtacagat atggtgcgga aagagggata
    24661 aacacttttc aattcatagc tggaaaggag gtgagattat gaaaccgtct gacttccaaa
    24721 aaacaattca gtgtcagttt gaatgtaagc tgaaaaaagt tgtcaaaggt attatctgga
    24781 actaccgtaa agaattaaaa cgaagaaaaa acaaggaaat atcttttagc gaattaccag
    24841 acattacggt agaaggtctg gcaacatggg acgactacga aacaaactac acaattttta
    24901 atgtgtgtgg catagatatt aaagtccttg atgatgaact tgcagaagct ctcaaacagc
    24961 tacccgaaaa aaaacgtaac aatgtattga tgtattactt cttggaaatg agtgatacag
    25021 agattgcaga tattatgaat tataccagag gggctgtgtt caaacacaga caccgtgcac
    25081 tagaaactat gaaagagata ctaaaggaga agaaatagaa atgaagaaaa agtacaagca
    25141 cccgtcttat tatttgattt catcagctat ggatggggat gaaactgcga ttgagaaatt
    25201 actggcattc tatgacccgt acatatcaaa gtgttgttta cgtcctttat atgatgaata
    25261 cggcaatgtt tatattgttg ttgatatgga attaaaggga cgtattcgag aagccttaat
    25321 caaaatgatt ttagactttg agattgatat agatatagaa accgaagaag aataagcaga
    25381 taccagcagg gcgtgattgg ttaaattccc ttctttcctg ccctgctcct gcttttatac
    25441 atggaagcct acggctttcg ccgattgttc ttagacaact gaataaagca gacagatacg
    25501 tttgtgatac agcgagccac ggggactgta cgccatgacc tttccgacaa gaaagcgagc
    25561 gacccacgca gttgatccga gagcgacttg tggaatggtc gttttgccat gacctgctat
    25621 cacagaataa tgatacgtcc gcatggtgcg gttctgccca caagaatggg aatagttgag
    25681 atactaacgg agctttccaa agccgtctgt ctgcttatga taagacacac agaaaggagt
    25741 tgttgcaaca tgaacaatac tgatgtgccg atttgggaaa aatacaccct tagtatagaa
    25801 gaagcgtccc gatattttcg tatcggggaa aagaagttgc gtaaacttgc cgaggaaaat
    25861 ctggactctg gttgggttat cgttaatgga aaccgtattc agataaagcg aaaacagttt
    25921 gaaaaaataa ttgatacact ggacgaaatc tgatgtctta gagccgtaga tatggtataa
    25981 tattagtagc gtatcacggc tcattccatg acggaaagga gctttacact atgtcaaaaa
    26041 tgaaaagaca agacagtaaa ggacgcaatt tgcgtcttgg agagagccag agaaaagacg
    26101 gaagatacgt ttataaatat accgatatat tcgggaagcc acagtttgta tatgcttgga
    26161 aacttgtacc cacagacaaa acacctgctg gaaaacgtga tgatatatcg ttgagggaaa
    26221 aagaaaagca gataaaaaaa gaccttgacg acggtatcga cacagtgggt ggtaaaatga
    26281 cagtctgcca gctttacgaa aagaagaaca atcaaagaaa gaacatcaag agaaacacaa
    26341 aaataggacg acagtatctt atgaacgcac tggaaaatga cccattgggt atgagggcga
    26401 ttgatacggt caagcagtcc gacgctaaag aatgggctat cagaatgaat gacaaaggtt
    26461 attcctacaa aacgatagat aactataagc gttccttaaa ggcttcattc tatatggcga
    26521 tacaagacga ctgtatcaga aaaaatcctt tcaatttcaa gttgagtgat gttctggaag
    26581 atgatatgga agcaaaggtt atcctaacac cagagcagga agaaaaactc cttgccttta
    26641 tggaaacaga taatgtctac agcaagtatc gtgatgaagt tattcttctg ctggaaacgg
    26701 gacttcgtat ctctgaatta tgcggactga caacacacat tgatatgctt aaccgtgtga
    26761 ttaacataga ccaccagcta ttgcgtgata cagaggtggg ttactatatt tccacaccta
    26821 agacaaaaaa cgggaagcgt gagcttccat tgacagaaag agcatatcag gcacttgaac
    26881 gaattttaaa gaaccgagga aaagcacaac cgcttgttgt tgacggttac agcaacttct
    26941 tgttcttgaa ccgtgaggga ttgccaaagg tggcaggaaa ttatgaaagt atggtgcgtg
    27001 ggctgattaa gaagtacaac aagacgcata aggacaagtt gccaaacatc acgccccatt
    27061 cattcagaca tacttactgt acaaacatgg caaataaggg aatgaaccct aacaccctgc
    27121 aatacattat ggggcacgca aacataacca tgacattagg gtattatgct cacggtactt
    27181 tccagtctgc aaaggctgaa ttagaaaagc tggcttctta atatcgaaaa tgtatcttac
    27241 tacttattta ctacttttgg ttgcattttc atgctggtaa atgccatctt atgcgaggta
    27301 tcttccaaaa ggaaaatgcc aataaagccc gaaaatatgg gatata
//
LOCUS       DAEPUT010000053        27094 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.055, whole genome shotgun sequence.
ACCESSION   DAEPUT010000053 DAEPUT010000000
VERSION     DAEPUT010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27094
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.055"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            122..751
                     /locus_tag="KRL22_002418"
     CDS             122..751
                     /locus_tag="KRL22_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272895.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTKNTMLDCRCPESISLLKRNNLINDFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            752..1534
                     /locus_tag="KRL22_002419"
     CDS             752..1534
                     /locus_tag="KRL22_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272896.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKEKMVEAYE"
     gene            1527..2405
                     /locus_tag="KRL22_002420"
     CDS             1527..2405
                     /locus_tag="KRL22_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272897.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRISSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKIKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            2438..3397
                     /locus_tag="KRL22_002421"
     CDS             2438..3397
                     /locus_tag="KRL22_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1272898.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            3711..4403
                     /locus_tag="KRL22_002422"
     CDS             3711..4403
                     /locus_tag="KRL22_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1272899.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            4413..5417
                     /locus_tag="KRL22_002423"
     CDS             4413..5417
                     /locus_tag="KRL22_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1272900.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV
                     "
     gene            5665..6516
                     /locus_tag="KRL22_002424"
     CDS             5665..6516
                     /locus_tag="KRL22_002424"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH1272901.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDRVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKLLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            6620..7366
                     /locus_tag="KRL22_002425"
     CDS             6620..7366
                     /locus_tag="KRL22_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272902.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALLRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            7366..9282
                     /locus_tag="KRL22_002426"
     CDS             7366..9282
                     /locus_tag="KRL22_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272903.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVIMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKSISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGITYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            9561..10478
                     /locus_tag="KRL22_002427"
     CDS             9561..10478
                     /locus_tag="KRL22_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH1272904.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEISVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILSEIEKMKKIY"
     gene            10556..11293
                     /gene="cas6"
                     /locus_tag="KRL22_002428"
     CDS             10556..11293
                     /gene="cas6"
                     /locus_tag="KRL22_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH1272905.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKSMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            11299..13176
                     /gene="cas8a1"
                     /locus_tag="KRL22_002429"
     CDS             11299..13176
                     /gene="cas8a1"
                     /locus_tag="KRL22_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HBH1272906.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNLIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKKYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTCINELFERNNSLKAQKSEYSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFTDKYANKKIQSIYDYKLK
                     SNVLDLLLKNRDLKHLTNNILRNKVKNDMESNNKSNISGIDCFRVVQLRVLINSYKKG
                     VYKMDSKNLEKNDEKLKIIYYLGCDIHDYFVNKNSKNKIDGVSYKLLNSVKVGNKSDF
                     MDTIIRVFMSAEKQIPAFILDIEIEKDLDFESIGHAFISGLISGKYEGKDKLPNEKEE
                     K"
     gene            13178..14092
                     /gene="cas7i"
                     /locus_tag="KRL22_002430"
     CDS             13178..14092
                     /gene="cas7i"
                     /locus_tag="KRL22_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBH1272907.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRADGNMYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGFADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            14094..14795
                     /gene="cas5b"
                     /locus_tag="KRL22_002431"
     CDS             14094..14795
                     /gene="cas5b"
                     /locus_tag="KRL22_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HBH1272908.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKVLN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVDDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            14806..17127
                     /locus_tag="KRL22_002432"
     CDS             14806..17127
                     /locus_tag="KRL22_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBH1272909.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTERLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLADLTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIHENKHTKQIFGKGVLISNEIDQFI"
     gene            17142..17693
                     /gene="cas4"
                     /locus_tag="KRL22_002433"
     CDS             17142..17693
                     /gene="cas4"
                     /locus_tag="KRL22_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HBH1272910.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEMLIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMQLSP
                     PKIEKKHYCTKCAYYEFCFVKEE"
     gene            17696..18676
                     /gene="cas1b"
                     /locus_tag="KRL22_002434"
     CDS             17696..18676
                     /gene="cas1b"
                     /locus_tag="KRL22_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HBH1272911.1"
                     /translation="MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIVDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            18679..18945
                     /gene="cas2"
                     /locus_tag="KRL22_002435"
     CDS             18679..18945
                     /gene="cas2"
                     /locus_tag="KRL22_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HBH1272912.1"
                     /translation="MFVIVTYDIVEARSLNRIRKILRKYLTWTQNSVFEGNITDGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     repeat_region   19129..19815
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=19129..19157
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            20004..20432
                     /locus_tag="KRL22_002436"
     CDS             20004..20432
                     /locus_tag="KRL22_002436"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBH1272913.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(20888..21667)
                     /locus_tag="KRL22_002437"
     CDS             complement(20888..21667)
                     /locus_tag="KRL22_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272914.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            21991..22536
                     /locus_tag="KRL22_002438"
     CDS             21991..22536
                     /locus_tag="KRL22_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBH1272915.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            22568..23704
                     /locus_tag="KRL22_002439"
     CDS             22568..23704
                     /locus_tag="KRL22_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HBH1272916.1"
                     /translation="MEEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYDTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            23708..25099
                     /locus_tag="KRL22_002440"
     CDS             23708..25099
                     /locus_tag="KRL22_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HBH1272917.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIINIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            25175..26050
                     /gene="dpsA"
                     /locus_tag="KRL22_002441"
     CDS             25175..26050
                     /gene="dpsA"
                     /locus_tag="KRL22_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HBH1272918.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            26053..26643
                     /locus_tag="KRL22_002442"
     CDS             26053..26643
                     /locus_tag="KRL22_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HBH1272919.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(26850..27050)
                     /locus_tag="KRL22_002443"
     CDS             complement(26850..27050)
                     /locus_tag="KRL22_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272920.1"
                     /translation="MEKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
BASE COUNT        10913 a         2585 c         4558 g         9038 t
ORIGIN      
        1 tattaaaaaa tgtagataaa aattgtttta ttaagaaaaa attaatatat tgacaaaatt
       61 taagtgctca tttaaactat taattgataa taatattcaa tattaaataa taggaggcgt
      121 tatgaataaa tatcttctaa taaatccagt ggcagaaaga atgtatggag aaaagtttca
      181 ccttattaaa gcaaatttga taaaaaaggg gtacataata gcagaatgtg aaccacagtt
      241 agagtatgta aaaaagcagt acaaagagta tacaaaaaag actaaaaata caatgttgga
      301 ttgtagatgt ccagaaagta taagtctttt aaaaagaaat aatttgataa atgattttga
      361 agtacctatg atagaaccaa tattagtaag gacttgtagg gttttatacg ataaatatat
      421 aaaaagtaaa gatgatatgt tggtagtaac ctgtccatgt acacaattaa gagactttgc
      481 aagtgaaaag tttaaggata agggtaatgc tatgttttat acatggaaag agtttgctga
      541 acaagaaggt gtaaaatcac ttggaaaaat agatgaatca ccaattccat taggatattt
      601 caaagatact tttgaaaaag ttcttgaagt atcaagtgaa gacgaaatat taagtgaaat
      661 acaaaaaata agaaatggct ttgaagataa gtatgacata gtagaaatgt tttattgtaa
      721 agatggttgt aataatggag atggtttgta aatggtcaat aaatttaata ataagttttt
      781 aaggctagta aagagtgttt tgatattttt tataattctt ttattatgga aaattacaaa
      841 ttatcttggt atttggagtg attatatatt accatcacct gaaaaggtat atagtacatt
      901 tttaaatatg ataagtgatg gttcaatatt tattaatgta tatgcaagta tgaaaagagt
      961 tttgataggt tttgcaataa gtactgctat aggtgtgcct ttagggatat tctttggaat
     1021 ttatagtgga gtatatgaat actttaaatc tctaataaat tttttaagga atacacctcc
     1081 ccttgcttta ataccaatgc ttatattatg gtttggtata ggagaggaat caaaaattat
     1141 aattatagtt ttagcatcct ttttcccaat ctttacaagc acattgaaag ggattaaaaa
     1201 ttgtgactca aaactgattg aagtgggtag agtatttgag ttttcaaagc ttcagataat
     1261 atttaaaata ataataccaa atgccattct tgatattgct gttgggttaa agttagctct
     1321 tggatatagc tttagagcaa ttattggggc agaacttgta gcagcttcat ctggtcttgg
     1381 atacttgata tctgatggaa aagaaatgtc tagaacagat gttgttattg taggtataat
     1441 cgtaattgga cttttaggaa taattacaga ttacatattt tcgattattg tgaagaaggt
     1501 aagtaaggaa aagatggtgg aagcatatga ataatttagt atgtgactct ggatatataa
     1561 ttagaaattt atataaaagt tataaagttg acaatgaaga acatgtagtt cttagtgata
     1621 tctctttaaa catagataga aaccatataa cagtaatttt aggtgaaagt ggttgtggaa
     1681 agactacctt gcttagagca attgcatcac ttgaaggtat aaatagtggt gaaattaggt
     1741 ttattaatga taataaagag tatagaccta atgttggttt tgtttttcag gagagcagat
     1801 taatgccttg gttaaacgta agtgaaaata tagcttttca taatcaaaga aaaaatacta
     1861 ttttaaacaa ggtacttaga aaatttaaac acaataaaag aattagcagt aaaattataa
     1921 atgataattt tagaagctta gaaacaaatg ataatttgaa caaatcaaat aaatataata
     1981 ggaaaagtaa tattgatgta gaaaaatatc ttaagatgat gaacttgcag aaatttaaaa
     2041 actcttatcc aaatgaattg tcaggaggta tggcacagag agtaagcata gctagagctc
     2101 tttctttcaa tccagatatg ttgcttatgg acgagccttt ttcggcatta gattatttta
     2161 caaggattga tatgcaaaat gaagttataa gaatacataa gtcaactaat aaaggcgtga
     2221 tatttgtaac tcatgatatt gatgaagcgt taaagatagg caagaaaata gttgttttca
     2281 cagacgaaag aaaaataaaa gaatttaata tagaagatgg ttataataga gatttaactt
     2341 cagattacta tattaaatta aaaaaagata ttttaatgac aatgaaatca aataaaggca
     2401 tttaaagaaa ttaataatat tttaaggagt aaagtaaatg aaattaaaaa agctattgat
     2461 aggtataacg atattaacac ttgcaacagc atctttagct ggatgtgcta aaaaaaataa
     2521 tggagaaaaa ctttcagaaa taaatttaac ttatgtaaaa tcaccattaa atgttccttc
     2581 tataattcag aaacaggatg atttatttgg aaaggaattt aaaaaggata atataaaagt
     2641 taacttccac gaaattacta caggtccaga gcaaacacaa gctttagctg ctggagaaat
     2701 agacttctta catgcactag gtggtacatc agctttaata gctgcatcta atggagtaga
     2761 gttaaagata ttaaacactt atagcaggtc accaaaagga tttatgattt tgactaataa
     2821 taattcaata aaatcagcag cagatttagt aggtaagaag gtggcaggcc caaaagggac
     2881 tatattacat caggtattga tttcagcact tgataaagaa ggattaagta tggatgatgt
     2941 ggaatttgtt aatatgggta ttccagaggc atcagcagct ctttctgatg gcagcgtaga
     3001 tgctgcattg attgctggtc cagcagctct taaagctatg aagtcaggta gtaaacttgt
     3061 agcaaatggt gaaggtttag tagatggtat aatagtaact gctgttagca cagactttgc
     3121 agagaaacat ccagaaatag ttgaaagatt tatgaaggtt gaaaaggaaa ctttagaata
     3181 tgtaaataat aattttgatg aagctatgga aaaagtagct aaagaagttg atttaagtct
     3241 tgaagaaact aaagaattat atgcttggta tgattttagt ttagatataa cagataaaga
     3301 catatcttcg cttgaagata cacaagactt cttaataaaa aataagttac aagagaaaaa
     3361 agtgaacata aaagaattaa tctataatgc taagtagaaa ctatgataaa ataatactaa
     3421 gtaagaaata taataaaagt ttaagttacc ttattaaggt aactttttct attttgaatt
     3481 agtaatttca atttatttta gaatgattag ttgataataa tgattaatta atcataaaaa
     3541 gatacttttt tatagagttt tattaagatg tctaataata tggttatact tatgaagtca
     3601 gtaattgtga agttagtaat atgattaaat ttatatattg taaaaagatt ataatatatt
     3661 aaaattggac tgttatatga tgagtaaata ggtatattag gaggaattat atgagttata
     3721 aagtatatat tgtggaagat gatatatcaa taagtacatt acttaaagat tatattgaga
     3781 aatatggatt tgaagtgatt gttgaagaaa actttgatga tataatgatt acatttgaaa
     3841 gttttaagcc acacttagtt ctattagatg taaatttacc taaatttgat ggtttctact
     3901 ggtgtagatg tattaggcaa cagtcgaatt tacctataat ttttatatca gctagagatg
     3961 gtaatgtaga ccaaattaga gctttagaaa gtggagcaga tgattatata acaaaacctt
     4021 tttactatga tgtagtaatg gcaaaaataa agagtcatat aagaagggta tatggtgaat
     4081 attcacctaa aatagacgaa agaatagtgg agctagatgg attaaagttt tatccagaga
     4141 ggttagaact agaattaaat ggtgagaatc taattataac taaaaaagaa ggtatactga
     4201 ttgaatgtct tatcaagaga tacccaaaag tagtaagtag agattatctt ttagaaaaga
     4261 tatgggatga tattgagttt gtagaggaaa atactttaaa tgtaaatgtt agcaggataa
     4321 ggaaaagatt tgaggaatta ggtatagata atgctgttca gactgtccga gggttaggat
     4381 ataaattaaa taagaattgg taaggagaaa gtatgaagtt atttttaaaa gattataaag
     4441 gttatatttt tatatattat ataggcatag ttatgacaat tatttactgt aatcttatga
     4501 agtttattag ttttggagag agtttatata ttcttttatt tagttctttt atattgttat
     4561 gttttttaat atataagtat tataaaaata gagaagtata taatctgttt gaaaaaggag
     4621 tacattcttt ggaggagtca tttttgtatt taggaagctc attcttgggg agaaatatat
     4681 cagttatttt aaaacaacaa cataaattgt atcaatcaat gatacaagag cataaaaaga
     4741 tacatagtga acatttaact ttcatcaacc aatggattca tcagatgaaa acaccaatat
     4801 cagttataag ccttcagctt caagattatg agggagaaga agtaactgaa aatataagaa
     4861 aagaaataga tagattaaat aaagggttag atatggctat gcattttgca agggcagata
     4921 attttcagaa agattttata gttgaaaaag ccaaattaaa tgaaattgta tctagtattg
     4981 taaatgaaga aaaaaggtta tttataaaaa gtggaatgat tcctaagatt caagtagaca
     5041 aatttactta tgtttataca gatgtaaaat ggatgaaatt tataataggt caattaatta
     5101 caaatggagt gaaatattct aaagattata gtaactacct aactataaaa tctgaagaaa
     5161 ataataaata tgtaatttta agtataatag atgaaggaat tggaattgtt tctaaagatt
     5221 taaaaagggt atttgaccca ttttttacag gagaaaatgg tcgtaagttt ggagaatcta
     5281 caggtatggg tctttatcta gtaaaaaagg tatgtgatga tttaggtcat aaagtaagta
     5341 taaaatcaga agtaggaaaa ggtacagaag tttcaatcta ctttaataaa gatgtaaata
     5401 gtttaataaa ggtgtaaatt atctgttaca atagggtttt tagttaattg tactttttta
     5461 ttatacaatt tattaaatga aatattcata gttaaataat caaaatttaa gagagtttat
     5521 ttgcaaacct tacatagatg taaggtttgt gtaatgtttg cagatagtta aattttctaa
     5581 tctaaattac aattaatata agaaataaca taagagaaat aacataaaaa aagaaatttt
     5641 gtaaaaaagg aaggatgttt attgatgagt ttagatgtta tttttatatt gaaatcagtc
     5701 ataatagcta tagtagaggg gcttacagaa tttattccag tttcatctac aggtcatatg
     5761 attttggttg gtaatttaat agattttaag gggcaatttg ctgaaatgtt tgaggttgta
     5821 atacaacttg gggctatatt agcagtagta gtactttatt ggaaaaagat aaaagatagg
     5881 gttatagaat tttttaaatt tatatttact ggtggaaaag aaggaaagat tggttttaga
     5941 tttggaatga atgtaattat aggttgtata ccatttgcga ttataggggt tctattttac
     6001 gataatataa aattattgtt taatttacaa tctgtaatta taggatttat agtgggtggg
     6061 attttattat tagtagtaga aactttgttt agaaaaaaga atcattccac agataatata
     6121 gataaaatta ctccaataca agctttaaag gttgggacat tacaagtttt gtctgcatgg
     6181 ccaggtatgt caaggagtgc atctactatt atgggtggat ggatagcagg acttaattct
     6241 cctacagcag ctgagttttc tttcttttta gcagtaccag ctatggtggc ttcttcagga
     6301 aaagatttat ttgaatttga ttattcaata atgacaccaa cattgtggat tgctttggta
     6361 gttgggttta tagtagcttt tattgtatca ataatagtta tggaaaaatt cgtgaatttt
     6421 ttaaagaaaa aaccaatgag agtgtttgct gtatacagaa taatcatggg tgtagtactt
     6481 gcagtattag cttttactaa cataattagt gtatagaaaa aatagattta ttatctataa
     6541 aaattaaact aagataaatt ataattaaca attatatata tgttatttca aaaattaaat
     6601 taggaaggat agttaaataa tgaaaatttt aactgtaaat aatttaagta aagtatatgg
     6661 taaaaaaata attttcaacg cattaaatga cataaatttt agtatagaag atggagaatt
     6721 tgtaggaatt atgggtccat ctggtagtgg aaaaactact cttttaaata tgatttctac
     6781 tattgacaag ccaactacag gaactatgga attaaagggc aagaatcctt tattgttaag
     6841 aggtgaggaa cttgcattac ttagaagaag agagttaggt tttgtatttc aggattttaa
     6901 tttattggat acattaacta taggagaaaa tatagtattg ccattgacat tagataaggt
     6961 cagtgtaaaa gagcaagatg agagattgaa tgaagtatct acaatattag gtataaaaga
     7021 tttattagga aaaagaactt ttgaagtatc aggtggtcaa gctcagagga ctgctattgc
     7081 tagagcattg attaacaatc catcaatact tttagcagat gaaccaacag gtaatttaga
     7141 ttcaaagtca tcaaaggttg taatggagct atttcaaaag ataaataaag aaaataaagt
     7201 tactactatg atggtaactc atgacccatt agcagcgagc tactgtagta gaatcttatt
     7261 cataaaagat gggtctatat ataatgaaat atataagggt agtagtagag agcagtttta
     7321 tcaagagata atggatgtac ttacattatt gggaggcgat aactaatgaa tataaaacag
     7381 tttgctatta acaatatttc aagaaatatt aaagcgtatt taggatactt agcaagtatt
     7441 gttatatcat cttcactgct attttctttt attatgttta caagtcatcc agatttagat
     7501 gtatctcaat ttcctgatta tttaaaagaa ggtctcaaga tgagtaagat aattgcatat
     7561 ctattcttat tcttctttgt gttttattca gttagtgtgt ttcttaaaag tagatataaa
     7621 gaatttggaa tactttatat tacaggtata tcaaagcgcc aagtaatgaa attaatcttt
     7681 atagaaaata tgataataaa tatagtatct tctgtaattg gaataataat aggcttaatc
     7741 tttgcaaaga tatttttagt gattatgtct acttttttag aattatcacc attaaaattc
     7801 tatataccat ttaatgcgat attgtctact ttaatctatt ttatgatttt agctgtatta
     7861 acatcaatat ttacttcttt tatagttaaa gaaaatcagg tgttgaagtt acttaaaggt
     7921 acaaaaactc caaaaccaga gcctaaaaca tcactaatgc ttgctatatt aagtatttgt
     7981 ttgtttataa tagcgtatta taatgctatt acctcaaccg accaatatac aacatatctg
     8041 cgcttagttc cagttacatc ccttactata gtagcaactt acttgttctt ttctcaattt
     8101 agtgtatttt ttatgaagaa gctaaaacta aacaagagat tttatagaaa aaatacaaat
     8161 atgctttgga tttcgaactt gatttataag gtaaaggata atgctagaat atttttcttg
     8221 ataactataa cttctgcagt agcatttact gctataggta cagtttattc cttttggaaa
     8281 gatgtagagc gtcaaattaa tttaatatat cctaacacaa tatattattc aacaatgaca
     8341 ttgcataatg accctaaaaa gcctgatagc aaagaaaaag acaaggaaag aatgatgttt
     8401 atagaaaata atctaaaaaa agagaatgta gactatacaa ggactaatgg tgaatttaaa
     8461 actgtatttc ccaagaaaag tgattttaat gtcagaatta tgaaagaatc taagtactta
     8521 gaaattacag aaactatagg ggttaagtct ataagttttg aagataatga atgtatatca
     8581 ttattatcat caagtttacc aggaaataat aacgtcaaag aaaatattat tgtagggaat
     8641 aggggtttaa aggtggcaaa acaagtggaa gaatgtgtta tgccagcata ttacaaaaat
     8701 atgtatgtgg taaaggataa tttttatgat agtatagaat caaaatttat agtggataga
     8761 tttactgcat ttgaagtaga ggattcaagt aaaactatag agatatgcag agaatttgaa
     8821 aataaattta ataatgagtc agggatgcaa ccatatttgt ttttctctaa agaattaatg
     8881 ataggaactg ggaaattaat gtattctaca tttatatttt tagcaatatt tataggttta
     8941 attttctttg ttactacaag tagtttttta tataataaat tttatatgga ttgccaagtt
     9001 gataagaaaa agtatgaaca gttaaataaa ttggggataa catataatga gattaaaaaa
     9061 gcttcaacaa ttgagattgg aatagtattt ttgtttcctt atgtagtggc tgttatacat
     9121 tcaatatttg cacttactgc actgaaaaat tcttttgata tagaagtagc atcatcagct
     9181 gttttggtaa tgggaagctt gttcttggtt caaatagttt attttttaat tgtaagaaat
     9241 aattatttaa aagagataag gttaaattta gtcaattttt agttactatt attaaatgat
     9301 aataaaaagg gtttaaaatt aattaatatt actggaatta tagatgttta ttttttcagt
     9361 aatatttttt attgtattaa ctattaaaat tttgtacaaa tataaaatat aatatggtaa
     9421 atgtcaaaat tataaaaaaa ttctacttat ataaaatata aagaggttat atgtacatat
     9481 gtgtagaaat aaataataaa aatatcaatt aatgttatta gggggggtta ctcattagta
     9541 aattagctaa tacacttaga atgatgatat taattcaaag tagaggcaaa atgaaatgca
     9601 aagaattatc agaagagttg gaagtaagtg aaaggcaaat aaaaagttat aagatgtatt
     9661 tagagcaagc tggtatattt ataaattcaa cacctgggat ttatggtggt tatgaaatag
     9721 ataaatgtaa tagcatctca ttaattaaat tattagatag tgaagtttca attctagata
     9781 tgataaattc acagttagag tataataatg atatttacaa aaatgaattt aataatattg
     9841 tagaaaaaat aaaagcagta ttaaatacag gagaaaaaag cgatacatat atggattatt
     9901 ttacagttca agcacaacgt aattgtgatt atgagtctga aaaaaataag tgtaatgaaa
     9961 taattagagc atataccaca aaacacaaat tttggataga atattattca ttaaattcag
    10021 gaaatagtga aagaattgtt catccatatg gtttatttaa ttataaatca gatacttata
    10081 tggtagcttt ttgtgaaaaa agatttaagt ttatagactt taaattatgt agaattaaag
    10141 attataaggt tttagaagaa aaatataatg tagataaaag ttttagttgg gatgaatata
    10201 gtaaaaatag tataggaatt tataagggag aagaaattag tgttgttata aaaattagtc
    10261 atccattttc aacaattata aaggaaaaag tttgggttaa taatcaacaa atcatagaat
    10321 atgatgataa atctataatg tttaaagcta aaatgagagg ttatgaggag ataaaaagtt
    10381 ggattttaag tatgggagct tatgttgagg ttgtagaacc agatagactt agaaatgata
    10441 tattgtcaga gattgaaaaa atgaaaaaaa tttactgatt ttttcaaata atttatactt
    10501 ggaccaatat acttcacagt ctagtgttaa tatattaatt gagagaggtg atattatgaa
    10561 aatgaaaatt gaatttagta caggttgtat accaatatct tataattcgc tctttatgag
    10621 tattataaaa gaagcaataa gaaaatctaa tgaagattac tataaaagca tgtactatta
    10681 taaagaaaag aataataaaa aaactaaaaa ttttacattt tcggtttata taaaaaagta
    10741 tagtattgaa ggtgacaatt ttattataga agataaagta atattaaata taagtactcc
    10801 agatttagaa ttgggttttc atatatacaa tgggttaatg acttctaaaa aatgtttata
    10861 taaagactac gaacttacaa gaattagaat cgatttatca agagaaaaga aggtaacaga
    10921 agaaagggta ctatttaatg cattgtctcc aatctgtgta aagtctaaag aaggaaaatt
    10981 cttggagata actgatgata gatacataga agaactaaac tatataacta atgaagtggt
    11041 taaaaattat agggggaatg gattaaaaag aaagttagaa tttgaaaata taggtctcaa
    11101 aaaggtagta gttaaagaga gcttaagaga atttaaaaaa ataacaggta aagagtatca
    11161 atatattaat ggttacaaag gtaaatttat attgaaaggt gatattgatg atttaaatct
    11221 tatctacaat ctaggaattg gttttagacg tgctcaggga tttggagatg tagatatttt
    11281 agaatggagg tgagataaat gaagttaaga gtttatagag gagattggtt ttttaatatg
    11341 ggtatagttg gatttttaaa tataataaag aaagcagata aacaagctga aatatttatt
    11401 atggaagatt atatcgaatt tgatagctta tttcttgaaa actttcatga gtattatttt
    11461 aattacttta tggatgaata tgatgtatca aaaagaatta aaaaaaatat tgattatagt
    11521 ataaatttta ttaaatctaa gcctgataga atcaaagatg gaattaagaa aattaaagat
    11581 agtgtgaaac aacaaaatga taagattaaa aaatttgatg aagaaaaatt taacctgata
    11641 aaagagaagc tagatagtat gtctaagata aaaagttatg atgaatttga cagtttagaa
    11701 gctttagtag atgagactat agatatattt aaaataaaat caataaatga caggcttaca
    11761 gcaaatcttt ataaatatgt agttcaagat aattattttg gacaagttag tttttttaat
    11821 gttgctaagg cgaaattaga tttagatgga ttaaaacagg taatgtttaa tgattattta
    11881 agacaaatta tatattttgg agagttagaa gatttattag aagagaatga ctatgataag
    11941 ttgaaaaact atttaaatga tagattaaat agtatagcta aggatataaa tgaaaaaaaa
    12001 gttagtaagt ctagtataaa tactatagaa aaaattatga aggaaataaa taaaaacttt
    12061 ataaagaaaa ataaaagcat agaagatata aaaaagtata tggatagttt agaagtatgt
    12121 gaaatgtgtg gtttatataa gggaatatta gatgaatact cagaaagtaa ttttgctcca
    12181 cttggagtaa gcaccaataa tgctaggaat atgttttgga atcaggcgta tgtaccatca
    12241 atatgtgata tttgtaagct aatattgttc tgtactccag caggggctac ttatacaaga
    12301 aagaattatt taattaatga agaaaatgag ttttatttat ttgttaacat ggatacttgt
    12361 ataaatgagc tttttgaaag aaataatagt ttaaaagctc aaaaaagtga gtattcagat
    12421 tccaaagatg aaaatccttt taatcagctt ataaaaagta tagtagaaga aaatacatta
    12481 aaaagtgaat ggcaacttcg taatatactt tttgtggaat ttaaagcaag tatagattct
    12541 aaaaaatgta aaataaatta ttttaatatt ccaacttatt tagcaaaatt ttttacagac
    12601 aagtatgcaa ataaaaaaat acaaagtatc tatgattaca agcttaaatc aaatgtacta
    12661 gatttactct tgaaaaatag ggacttgaag catctaacta ataacatttt aagaaataaa
    12721 gttaaaaatg atatggaaag caacaacaaa tcaaatatat caggaataga ttgttttaga
    12781 gtagtccaat taagagtatt aataaatagc tacaaaaagg gggtatataa aatggatagt
    12841 aaaaatttgg agaagaatga tgaaaagctg aaaataattt attatttagg ttgtgatata
    12901 catgactatt ttgttaataa aaattctaaa aataaaatag atggagtaag ctataaactt
    12961 ttaaattcag ttaaagtcgg aaataaaagt gattttatgg atacaattat aagagttttt
    13021 atgtcagctg aaaaacagat tccagcattt attttagata tagaaattga aaaagattta
    13081 gactttgaat ctataggtca tgcttttata tctggattaa tttctggaaa atatgaagga
    13141 aaagataaac taccaaacga aaaggaggaa aaataagatg aaaagaggat taacatttac
    13201 agtaatagca caggctcaaa gtttaaacta tggtgaaggg ataggcaata tatcagaatt
    13261 aaaaaaatta agtagagctg atggaaatat gtatacattt gcatctcgcc agtgtttaag
    13321 atatgacata gtacgattag cagcagaatt gtttaattgg aatttacagg ttgtcgataa
    13381 agaaaaaggt actattcaat ttaaagataa tataagtata agagaatcag aagaaatgga
    13441 tttatttgga tatatgaaaa caaataaaaa agatgagaaa gataaaaaag gaggttcttt
    13501 gactagagaa gctactgtaa gattaagtaa tgcgatttct cttgagccat atagaagtga
    13561 tatggatttt ttaaataata aaggatttgc agatagaata ggagaacacc ctaatcttgc
    13621 caacatagag caacatttaa gttactatac atatacggtt actatagatt tatctaaaat
    13681 aggtaaggat ggagatatag aacttgataa taaagagaaa tgtagaagag tagtagaatt
    13741 tttagaaata ataaaagtat tgaatagaaa tattagaggt agacaagaaa acttatctcc
    13801 tctatttgta gtaggaggag tatatgaaat agcaaatcca tttttcttgg gtagaattaa
    13861 attaaaagga gataaaaatg gatttaaaat aaataagcaa gctatagaag aagtaattca
    13921 aggtactttt ttaggaaaag atttaaaaga atttacctat gttggaatgg tagatggggt
    13981 atttataaat aaagaagaat ttaagggatt gtttgaagat aattttttaa gtgtagataa
    14041 attttttgga caactagtta aagaagtaaa ggaatattat ggggtgaatt aatatgaagg
    14101 ttttgaaatt agatttattt caagaaactg catgctataa aaaaccattt gctatgaaga
    14161 ttacagagac atatccactg cctccatatt ctacaataaa tggattaatt cacaaagtat
    14221 taaatgctac agaatatata ccgtttaata taagtgtaca gggaacatat gaaagtatat
    14281 ttaataatta ccagacaaca tatttttata aaaaagatag tattacatct atgccaatga
    14341 atagtcatat gctattgaat gtaaatttga taattcatat aggtggggat tttgatttat
    14401 tggaagaaat atatgatagt ttattaaatt atgacgagca tttatcatta ggtagaaaag
    14461 aagatttagt aagaattaat gatattagat ttgtagaagt caataaattt gaagtagatg
    14521 aggatataca attagatgat tatgaaaatt ataagttatc agaatgtaat ataagaatgc
    14581 ctatatatat accaaaaaca agtttacaag atacagatat agatggtata agttataggc
    14641 tcaataatta ctatgataat aatgctgtgg aagataaaaa aagggtttgg aataaggtag
    14701 atagttatta tgttgatgat ggaaatacta tatcaattgg agatatatta ttagataatg
    14761 aaggagattt attatatttt aataatataa attaggaggg agagtatgtt atatgctaaa
    14821 tctaatccag tggaaacact tagagagcat actgatgaac ttttaaaaca aatgaatgta
    14881 ttaagagaaa gttatggaaa aaatataaat agcttagatt ttctagaaga ggagatattt
    14941 tggcaattac ttgactttgt tatagaattt catgatattg gaaaggcatt ttcaccgttt
    15001 caagagttaa taaaaagcag aatggatact aaaataaatg aacctaaaat agtaactcat
    15061 ttagaaaata atgtaggcca taattatctt tctcctgcat ttattgatta tagttatata
    15121 gacaggaaaa aaaataaaga acttagagca gtattaaatc aagttattgt atatcatcat
    15181 gaaagagata tctttataga taaagatttt aaaaatttaa tacaaaaaat attagatgaa
    15241 gatttaataa ataaagttta tgaactacag catgaattta aagttagata tccaataaaa
    15301 acagaaagat tgagtaaagt atatctacaa agtgtagaaa aaagaataga taaaaatcat
    15361 aagtactata atttatatat tatgttaaaa ggaatactac atagactaga ccatagtgct
    15421 tctgctcatg aagttgtgga atgcaataat gttataaata taggagaaca gacagaaaat
    15481 tatttaatga aagagtttgg tagtttgaga gaggctcaat catttgctaa atctaataga
    15541 aataagaata taatactgat tgcatctaca ggaatgggaa aaacagaaac cgccttaatt
    15601 tggatagata aagacaaggc attttttaca cttccattaa gagtaagtat aaatgcatta
    15661 tttgatagag caaaaaatat agttggagtt ggagaatcaa atgatacatt cttaggtttg
    15721 ttacattcaa cagcaataga ttatctagaa gaaagtaatc aagaaaattc aagtgagatt
    15781 gtagatttag caaagttatt atcttgtaaa ctgacatttt ccacaataga ccaaatattt
    15841 aaatttcctt ttttgtatag aggctatgaa aaagtgtact caacattagc atattcaaaa
    15901 gtagtaatag atgagataca agcatattca ccagaaatag cagctgtatt ggtaaaaggt
    15961 atagaaatga tacataagat aggtggcaga tttatgataa tgacagctac tatgccaacc
    16021 atatatatag atgaattaaa aaaaagaggt gtaatgaata gtaacttagc tgacttgaca
    16081 tgtaacacag aaaaaataag acactgtgtg tctattgtag aaaattcaat agatgaaaac
    16141 ttaggtaaaa taatacaaag tggaatgaat aaaaaagttc ttgtaatagt aaatacagtt
    16201 aaaagtgctg tagaaaaata tgagttaata gaagaaatag ttaaaccaaa aggaatagat
    16261 gtcaacttaa atcttttaca ttctatgtat atacaagaag atagagcaaa attagaaaaa
    16321 tatataaaag aatttgcaga tagtgatagt aatggtattt ggattactac acaattagtg
    16381 gaagcatccc ttgatattga ttttgatgag cttcatacag aaaattcaac acttgacagt
    16441 ctatttcaac gatttggtag atgttataga agtcgtgagt atgaagaaaa tagcccaaat
    16501 atatttatat atacagaaaa agctacagga ataggtagta tttatgataa ggatattgta
    16561 gaaaaaggac ttgagctact gaaaactttt ataaatggaa aagaatgtgt gaagatgaaa
    16621 gaaaaatata aggtagaaat ggttaagata ctatactcta aagaaagtct agaaggtaca
    16681 gcttttgaaa agagatttac cagtgcttta aatattttag atactataac gccatatagt
    16741 ttaggttcta aagatgcaca aaatatactt agaaatattg aaggatatac agtaattcca
    16801 gaggatatat ataataaaat tgaagaaact ttaatcaaag attatgaaga gttgggacaa
    16861 gagcttataa atgcatatag taatgatgat agacaattga taaataaaat aaagtctaag
    16921 agaaaaaaag caagaagaga gataattaaa aaaactgtaa atttaccaat atataaagct
    16981 aaacaaaatg taattgacat acaggtgaaa ggtcttgaag atttaaaaat acttttatat
    17041 aaatatgata tacacgaaaa taagcataca aaacagatat ttggtaaagg tgtgcttata
    17101 agtaatgaaa tagaccaatt tatttgattt ttatattaac aatgtggcta aaatttacta
    17161 aagaaggtga ttttgtgcca atagatttag aagtattaaa agttcaaggt gtaaaaataa
    17221 attattatta tgtatgtaaa agaaaattat ggctattttc taaaggaata accatggaac
    17281 aaaatagtag tagagtattg tctgggaaga tagtacatga agattcatat aaaagaatga
    17341 aaaataaaga aatgttgatt gatgatatct tgaagctaga tataataaag gacgagtatg
    17401 taaaagaagt aaaaataagt tcaaagatga aagaagcaga tgaaatgcag ttatactatt
    17461 acttatacta tttaaagaat agtatgggta tagagaaaaa gggaactata aattatgtta
    17521 aggaaaagaa acaagaagaa ttgatattga cagaagaaaa agaaagaatt attgaaaaca
    17581 cacttataaa tataaatgaa ataaatatgc agttatctcc tcccaaaatt gagaaaaaac
    17641 attattgtac aaaatgtgct tattatgaat tttgttttgt gaaggaggag taacaatgta
    17701 taaagactat tatattataa gtaatgggga tataaaaagg aaagaaaata cgatttacta
    17761 ttacaattta gaaggtgaga aaaaaatatt accagtagaa caagttgatg atattcatat
    17821 atatggagaa gtagatttaa atacaaaact tataaattac ataagtaaat atggggtgat
    17881 gcttcatttc tacaattact atggatatta ttcaggtaca tattatccaa ggaagaaaaa
    17941 tgtatcagga ttcagtttag tatgtcaatc agcctgctat ttagataaaa atgaaagatt
    18001 atacttagca aaatcctttg tggaaagtgc atcataccat attttaagaa atatgagata
    18061 ttacaaagtt gatgaaagtt taattgatac tataaaggat gaactaaatg atttgaatga
    18121 tgtcaaagaa atatcagaac ttatgggtaa agaaggcaga ataagaaaaa catactataa
    18181 atcatttaat caaatattaa aagatgattt tgaattttat aaaagagaaa aaagacctcc
    18241 caaagaccca gtaaatgctc ttatgtcttt tggaaatagc ataatgtata cgaatgtttt
    18301 aagtgagata tataagacac aacttgaccc tacaataagc tttttacatg aaccatcaac
    18361 aaagagattt tctttaagtt tagatattgc agaaattttt aagccaatta tagttgacac
    18421 aataattttt agcctgatta ataataaaag aattaataag aatgattttg aatatcaaga
    18481 taaaatttgt tatttaagtg aaaaaggaaa gaagaaattt ttgcaagaat ttgaaaataa
    18541 gatgcagaca actataaaac atagaaatct aaatagaaaa gtttcatata gaatgtttat
    18601 aaggttagag tgttacaaat taattaaaca ttttataaat gatgaaagat ataaagtttt
    18661 aaaggtgtgg tggtaagtat gtttgttatt gttacttatg atattgttga agcaaggtcg
    18721 ttaaatagaa ttagaaagat acttagaaaa tatttgactt ggacgcaaaa ttctgttttt
    18781 gaaggcaata ttactgatgg aaagttacat aaatgtattt ctgaaataga aaatattatt
    18841 gataatagcg aggattcaat ctatgtttat gagataaaaa atcctaattc aattaaaaag
    18901 aaatgttatg ggattgataa gtattctgat gaaatgttta tataggtttg cagtgagcga
    18961 tatttatgct aaaataggtg ttaacagttg gaatataagg gattgaaggt gtatgataac
    19021 tgttatcaat tgcactactg ctcgctcact gcaaattttg atgtttttat tgaattataa
    19081 ttgcttgatt gaagtatttt caatgtattc aattatacct attttggggt tttatattaa
    19141 ctaagtggta tgtaaataag tttgaactgc tatcgcttca acttttcctt gtaggtttta
    19201 tattaactaa gtggtatgta aataaaacaa aaggagtggt aaaaatggct aagaaaaaag
    19261 gttttatatt aactaagtgg tatgtaaata aagtataaac aaatagtttt atctaaaaat
    19321 tataagtttt atattaacta agtggtatgt aaatttatta tgtattacag ctgtttcatt
    19381 attcttaaga tgttttatat taactaagtg gtatgtaaat taagtaattt cttcatcaag
    19441 taaattatca tggtagcgtt ttatattaac taagtggtat gtaaatgttg atgtctctct
    19501 agtaccttcc acagtttcta aagttttata ttaactaagt ggtatgtaaa taaagaacct
    19561 ctttttctgt ttcatcaact gtgtttaatg ttttatatta actaagtggt atgtaaatgc
    19621 atatatatat atcattaaaa taagttttaa agtcgtttta tattaactaa gtggtatgta
    19681 aatataagta aaacgggtcc gagcgctgct gctaatcctg gttttatatt aactaagtgg
    19741 tatgtaaata ggataaagaa aagactcaca caaggcacag tgtcaggttt tatatcaact
    19801 aagggtagat aagtagaata ttagcaatat caacgagtat ttagaaactt attttatatt
    19861 aataaagcag tatataaaat tgtagaatca acaatagcat atactaaaac atccacctta
    19921 tattaactaa atcatatcta aataaaatac acttacctat aaacattata aaatcaatac
    19981 aaaaatgagg tgaaataaaa tttatgataa agaaattaaa caataaagac ataaataaaa
    20041 tcatggaaat atgggaaaaa agtacaatca aagcacatga ctttataagt aaagaatact
    20101 ggcaaaataa ctataatact gttaaaaacg aatatatacc tatatcagat acatttgtat
    20161 atgatgatgg agatgaaata aaaggattta taagcataat agataaaagc tttataggag
    20221 ctttatttat aaagcccaaa taccaaaatc taggtatcgg aggtaaactt ttagattatg
    20281 caactaaaaa atataaaagt ctaagcttag cagtatataa agataataaa aaagcagttg
    20341 tgttttataa taaaaaaggt tttaatatag taaaagaaca agtaaatgaa gattcaggat
    20401 ttaaagagta cataatggaa tatagtaaat aattatgatt acattctatt aaaaggataa
    20461 ttaatttatt tgccatttga ttttttaaga gtaattttta aaatagacta tatgaagata
    20521 aagatattta ttataggtgt aagttaatca gaattgatat agctacaaaa gaggaaaata
    20581 aaattgtatg gtgtatttca gatttaacaa atttactatt taaagataat aagtttgata
    20641 taatattaaa gatactttca cctataaact atagggtatt tgaaagaatt ttaaataatt
    20701 atggaatgct aataaaggtt tgttaaaatt taataattat tagattatag aaaattgcca
    20761 tgaaattagt tcatcaagaa ctagtttcat agcaatttta attcttataa gtgtatttat
    20821 ttttacagat ttaaaaaact tatacagtat ctaataatgt aatcttatta ctttagccta
    20881 taaatattta aatcttaaaa tgttctcttt gagataagtt tatttcagag tcacaatttc
    20941 cacaacagta agatgttgag acatctttaa atttttcagt attctcatca aagttcattt
    21001 ttttctttgc aataattcct accttagtta aattagaacc acaattatta cagttttgaa
    21061 ttttgcatag gttatatagt ttatcaagtg taatatcttc taataattca tcacaattac
    21121 aacatctgat agaagaaact tcactacaca tttcaatagg ttcagcttct ttagaagaaa
    21181 atttatatgt tatgtcattt gatactttat aacctgtatc aaatatatta gaattacaac
    21241 ttggacataa gtactttgga agatatatat cttttttttc aaaagtatca ctactaatat
    21301 tacagtttaa ttcatctaaa attggtcttt catctaggtt attaccttta tttaagctta
    21361 gaagataatt ataaattttt ttatcttcat tctgctttga tgtatctaac aaatgctcca
    21421 ttatattagt gtattttttg ttttttgaag gcatgtttaa atccagataa ttgttttcaa
    21481 tagcaaagca tactatattg aaatagttat atttaactgc aaaaaataat aacatttcat
    21541 caaatacttt atctattatt ttgtcagaaa tacttatcca aaaatctggg gactctaagt
    21601 aaactttcct actaagttca tctaactctt catctatatt atttatatta ttttcattaa
    21661 ctttcatatc atcacttcct tttaaatatc ttgtgtataa actatttgtt actatttttt
    21721 atataaaata aaatcttata taaaaatata tcatattata atttacaagt atagtctaaa
    21781 tagagctgtt tttaagcaaa gttttataaa tgactattaa aatataaagt aacagtataa
    21841 agtttactta taaattaaat gtaaacctaa ataattataa tagttgacaa aaaaacgtct
    21901 ttattttata ctaaaacaaa gctttaatag aagctttgta tatgtacata taaactaaat
    21961 gaaataagac atatgaaggg aattataaaa atgaaaaata ctaaagtaaa tattcaagat
    22021 ttaactaaaa tgtcaatatg tgtagcatta ttgtgtatat catcttacat atatatacca
    22081 ttgccattta ctccagcagg agtaacagca caaacaataa tgataaattt aatagcttta
    22141 attttaacac caagacaagc atttagtaca gttggtgtat atataatgat aggtttaatt
    22201 gggattccag tatttggagg aggtacatct ggtattggaa agttgttaag cccaacaggt
    22261 ggtttttatt ttgggttttt gtttgcagca ctaattatta gtttattaaa aggacgaaat
    22321 aatgatatta agagatatat actaataaca atttttgttg gaatgcctat tatatatttt
    22381 atgggaacag tatttatgtg ctattttaat caaatgacag tagaagcagc actttttgca
    22441 gcagtagtac catttttaat tggagataca ataaagtcgg ttattgcatc ttttttaggc
    22501 actaaactga acaatgtact cagaagaaat ctatgataaa tctataatat aaggaagggt
    22561 gtaatgtatg gaggaagttt ttatattagg aggattgaga agtcatatag gtctaaaaaa
    22621 tggaattttt caatttgttc aacctgaatt actaggagca agtgttttaa aagatttaat
    22681 taaaaagtat gaaattgaca aaattgatga gattatatgt ggaaatgcag ttgggacagg
    22741 agggaatata gctagattaa tgactttaac agcaggagtg tcaaatgaag tacctgcttt
    22801 tactgtggat atgcagtgtg cttctgctat gatgagtata gacatagctt tttcaaaggt
    22861 taaatctggt cagtgtgatt taattattgc aggtggtttt gaaagtagtt ctctacaacc
    22921 aatgcgcaca tatcataaga atgataagcg atatgataca aataatccaa attatacagt
    22981 tgctcaattt tctcctgatg ataatagcca aaatagtatg ctcgaagggg cggaaagagt
    23041 agcagagcta tatcaaattg agaaagcaga cttggatttt tgggtaaagg aaagtcataa
    23101 aagagcaaaa gaagcaagag aagaaaaaat acttgaggat attatatctc ctataaataa
    23161 tagtacctat gatgaaggta tacgtgataa gatgagtcaa aggttattag ataggatgcc
    23221 atcaatttta ggaaaagaaa ctattacaaa tgcagcaaat tcatgtctta ttaatgatgg
    23281 agcttcattt attataatat gttctaagaa gtatttagaa catgtaaaaa agaagcctaa
    23341 agcaaaaatt attaatacat gcacaatagg aacagatgca accttaagtc caacatcagc
    23401 gatacaagca atggataaac ttttagagat agaaagtctt aattatttag atgtatctgc
    23461 tgttgaattt aatgaagcat ttgcagttat agatgtgttg tttcaaagaa agtatccaga
    23521 gttaatagat agatataata tatttggtgg agctttagcg tatggacatc catatggtgc
    23581 ttcaggtgca attattgcat tacatctttt aaaagcatta gaaaagacta agggtagata
    23641 tggaatttgc tctatagctg cagctggtgg tctaggttca gctttactgc ttgaaagggt
    23701 gtagattatg aactattatg aacttttaag aataaaaaaa gagaggcata aaaataaaaa
    23761 ttttttaatt atagatggag aaaaatatac ttatgaaaat atattgagtt atagtgagga
    23821 actaggaaag caaatttctt taggtgaaaa tatcccaatt ttaatatatt ctaaaaatat
    23881 aatgtttcag ttgattagtt tttttgctat taattattca aaaaatattc ctattatttg
    23941 tcattataat ctttctaaaa aagtattaga tgatatttta ttaaaaaata atatttcaat
    24001 cattatatct gatgaatcta tggacgttat tgatttatat gatgataaca ataatgaagt
    24061 agcaaaaaaa gttaattttt ctatttttaa tcctaaattt aatatatata tgtatcaata
    24121 taagaagctt ataaattatt tagataaaag tatttgtatg ggagctttat cttcaggttc
    24181 tacaagtgtt ccaaaggtat tatatagaac atatgagagt tgggctggat tttttcctat
    24241 acaaaatggt atttttaata tctctgggga atcaatcttg tttgttaatg gaacacttag
    24301 ttttacaggg aatctaaatt ctataatgtc agtattatat gaaggaggta gtattgtaat
    24361 aagttcaggt cttaattgta aatcatggat aaggacaata aaacaatata atgtaactaa
    24421 catatacctt atacctacaa aacttcaact tttggttaaa cacttaaaag aaccagtact
    24481 caaagttgta agtattttta cagggtctca attattattt gaagatactg caagaaatct
    24541 aaaaaaatat atgccaaagt ctgaaattat tttatactat ggggcaagtg aattaaatta
    24601 tattacatat ttatgctatg atgaactaat tgaaaaacct ctaagtgtag gcagaccatt
    24661 tccaggaata gatatatata ttagagaagg aaaaattttt gtgaatacag aatatgcagt
    24721 atataatgca accaaacctt attctgtcaa tgatattgga tattatgata atgatggata
    24781 cttaatattt gaaggaagaa gtgatgacat tataaatatt ggaggattta aagttagttc
    24841 tactaagatt gaaaatgaag ttaaaaaaat tcctcaaatt gaagatgcaa ttgtattgcc
    24901 gtactcagac actataagag gaaatcaaat tgtattattt gtaataacta tagacaaaat
    24961 tacgaagaaa gatttgttga ttaaaatgaa agataatcta atgaaaaatg aaatcccaaa
    25021 gaaaattatc tttttaaatt catttccata tacctcttct gaaaagatag atagattagc
    25081 attattaaaa atgttataag tataatattt agtaatttta gtgaaccaat gtattgataa
    25141 aaacatattg tatatagtaa aggaggctta caatatgtca aatcaatacg atataactgt
    25201 tattggggga gacctgcgac aagtgtacat ggtaaaaaaa ctaattaata aagggtattc
    25261 tgtagtcact tatggtatat caaatgaaat tataaatgga atcgttggaa aatcaacttc
    25321 actagctgaa gcactatcca aaagttccat tattttatgt ccaattccat ttacaaagaa
    25381 tcaagttaat attgaaaata cggatgattg tcttgatgct actattgata acttgctaat
    25441 taatttatct cctaatcaaa tattatttgg aggtaacata ccaactaaag tttgtaaatt
    25501 ttgcgagcaa cactctattc agatttatga ttttatgaaa atgaatgatg ttgctatttt
    25561 aaatgcagtt gctacagctg aaggggctat agcagaagct attaaaagaa gtataatcaa
    25621 tatacatcaa agtaactgtt tagtattagg ttatggaaga tgtgcacaaa tacttgcaaa
    25681 aaaattatac gctttggatg caaatgtatg tgttggcgca agaaataatg atgcaagaag
    25741 tacggctaat gcatttggat attccagtat ttctttaagt caacttgatg aaaaactttt
    25801 acaatttgat tatattttta acaccatacc agagtgtatt ttaacgaaag aaaggttaga
    25861 aaaagtatca caagaagtaa ctattataga tatagcttct tctcctggag gagtagatta
    25921 ttctgttgtt aaagaagcag ggattaatgc gactctttgc cttgggcttc ctggtaaata
    25981 ttcaccaaag acatctggtg aaattcttgt taacgctata gaaaatatta taaatgaaag
    26041 aagggattag aaatgagact tgaaggactt acaattggag taggatttac tggttcgttt
    26101 tgtacttatg ataaaatatt tatagagtta gagaatttgg ttaaagaagg agctaatgta
    26161 cacactatat tttcagatgt atcacaaaat atcgattgta gatttggaaa ttctgaagag
    26221 tttatgaaaa aagcatatga acttacagga aataaaccta tagttacgat tgaagaggca
    26281 gagccatttg gacctaaagg aattgctgat attataataa tagctccttg tactggaaat
    26341 actgctgcaa aattagcaaa tggtattaca gattcaccag tattaatggc agcaaaaggt
    26401 catcttcgta atgataaacc actagtaata tcaatatcaa cgaatgatgc tctaagcttt
    26461 aatttcaaaa atattggcat tctccttaat tctaaaaata tatattttgt accttttggt
    26521 caagataatt gcaaagcaaa gcctaattct atgattgcac atactgagct aataattcca
    26581 actatagaac ttgctctaga gaacaaacag ctacagcctg ttataaaaag tccacatcaa
    26641 tagaattggt tcttataata ttatgtatta gatacaatac tagcaaagag gctgtctcaa
    26701 aatagagaga agcctctttt tcttgttgaa atgatgaaaa tatatttaat ttcatacaaa
    26761 aaaatgcctc atggactaaa aagtctattt tgagctaatc tccgtaattt ttgctatatt
    26821 aaaattattt acttaatcca atttttaaat tagaatttat atcgttttga ctcttcaaat
    26881 atcaatctaa ctgttgttga tacaaaagaa gaggacataa ttaaaacaaa taccgatagt
    26941 cctctaataa acaaattatc tacataataa gttactattc caatacctcc aatcgttaaa
    27001 attacactta taatcaaaga aaaaacgcta attgttttta atttttccat gcttatcctc
    27061 cttcttataa acttcaaatt tatctatata atat
//
LOCUS       DAEPUT010000054        26960 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.056, whole genome shotgun sequence.
ACCESSION   DAEPUT010000054 DAEPUT010000000
VERSION     DAEPUT010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26960
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.056"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            20..481
                     /locus_tag="KRL22_002444"
     CDS             20..481
                     /locus_tag="KRL22_002444"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBH1272921.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(701..2152)
                     /locus_tag="KRL22_002445"
     CDS             complement(701..2152)
                     /locus_tag="KRL22_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH1272922.1"
                     /translation="MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            2622..3887
                     /locus_tag="KRL22_002446"
     CDS             2622..3887
                     /locus_tag="KRL22_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HBH1272923.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            3926..4381
                     /locus_tag="KRL22_002447"
     CDS             3926..4381
                     /locus_tag="KRL22_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272924.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(4525..4896)
                     /locus_tag="KRL22_002448"
     CDS             complement(4525..4896)
                     /locus_tag="KRL22_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HBH1272925.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(4899..5267)
                     /locus_tag="KRL22_002449"
     CDS             complement(4899..5267)
                     /locus_tag="KRL22_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1272926.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            complement(5537..6415)
                     /locus_tag="KRL22_002450"
     CDS             complement(5537..6415)
                     /locus_tag="KRL22_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1272927.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            complement(6432..6749)
                     /gene="trxA"
                     /locus_tag="KRL22_002451"
     CDS             complement(6432..6749)
                     /gene="trxA"
                     /locus_tag="KRL22_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH1272928.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            complement(6899..8131)
                     /locus_tag="KRL22_002452"
     CDS             complement(6899..8131)
                     /locus_tag="KRL22_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1272929.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            complement(8121..8792)
                     /locus_tag="KRL22_002453"
     CDS             complement(8121..8792)
                     /locus_tag="KRL22_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1272930.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            complement(8808..9644)
                     /locus_tag="KRL22_002454"
     CDS             complement(8808..9644)
                     /locus_tag="KRL22_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272931.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            complement(9670..10344)
                     /locus_tag="KRL22_002455"
     CDS             complement(9670..10344)
                     /locus_tag="KRL22_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1272932.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNVKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            complement(10358..11086)
                     /locus_tag="KRL22_002456"
     CDS             complement(10358..11086)
                     /locus_tag="KRL22_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH1272933.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            complement(11213..11902)
                     /locus_tag="KRL22_002457"
     CDS             complement(11213..11902)
                     /locus_tag="KRL22_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1272934.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNYFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            complement(11910..12473)
                     /locus_tag="KRL22_002458"
     CDS             complement(11910..12473)
                     /locus_tag="KRL22_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1272935.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPI
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            complement(12475..13443)
                     /locus_tag="KRL22_002459"
     CDS             complement(12475..13443)
                     /locus_tag="KRL22_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBH1272936.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYENIIDSVEGVI"
     regulatory      complement(13544..13587)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            13952..14581
                     /locus_tag="KRL22_002460"
     CDS             13952..14581
                     /locus_tag="KRL22_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1272937.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     gene            14556..14960
                     /locus_tag="KRL22_002461"
     CDS             14556..14960
                     /locus_tag="KRL22_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBH1272938.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            14963..15439
                     /locus_tag="KRL22_002462"
     CDS             14963..15439
                     /locus_tag="KRL22_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HBH1272939.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNNKIELS
                     KFDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPS
                     SLLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            15986..16651
                     /locus_tag="KRL22_002463"
     CDS             15986..16651
                     /locus_tag="KRL22_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBH1272940.1"
                     /translation="MIKLIGILIVIIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            16673..17605
                     /locus_tag="KRL22_002464"
     CDS             16673..17605
                     /locus_tag="KRL22_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBH1272941.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKSATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            17626..18267
                     /gene="pcp"
                     /locus_tag="KRL22_002465"
     CDS             17626..18267
                     /gene="pcp"
                     /locus_tag="KRL22_002465"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBH1272942.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(18387..18719)
                     /locus_tag="KRL22_002466"
     CDS             complement(18387..18719)
                     /locus_tag="KRL22_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272943.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            18984..19604
                     /locus_tag="KRL22_002467"
     CDS             18984..19604
                     /locus_tag="KRL22_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1272944.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     TGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKTGIKEPQYEEIIMTNFIK"
     gene            complement(19929..20753)
                     /locus_tag="KRL22_002468"
     CDS             complement(19929..20753)
                     /locus_tag="KRL22_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HBH1272945.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYALMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(20764..22167)
                     /locus_tag="KRL22_002469"
     CDS             complement(20764..22167)
                     /locus_tag="KRL22_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1272946.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIREYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRNTIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            complement(22171..22896)
                     /locus_tag="KRL22_002470"
     CDS             complement(22171..22896)
                     /locus_tag="KRL22_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1272947.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            complement(23008..23781)
                     /locus_tag="KRL22_002471"
     CDS             complement(23008..23781)
                     /locus_tag="KRL22_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272948.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNEPIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIAISIILMIVLTKITYENFTSSKRF"
     gene            complement(23787..24674)
                     /locus_tag="KRL22_002472"
     CDS             complement(23787..24674)
                     /locus_tag="KRL22_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272949.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSGDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            complement(24688..25668)
                     /locus_tag="KRL22_002473"
     CDS             complement(24688..25668)
                     /locus_tag="KRL22_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272950.1"
                     /translation="MFISLGILVLILMISIFITPVLETESYYIDKEKGRIEDTRSGID
                     IGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNEYKDISFWKVFNYRV
                     TNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALKSKIFVALLVPLVIY
                     SVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKYVILNIGIELLMFEG
                     WAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLSVVSNVNYYDLIFGF
                     NKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIKSDYISR"
     gene            26284..26460
                     /locus_tag="KRL22_002474"
     CDS             26284..26460
                     /locus_tag="KRL22_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272951.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
BASE COUNT         9456 a         4183 c         2994 g        10327 t
ORIGIN      
        1 aaaattggag gaaataaaaa tgatatatga aggaaaactt attggaaaag atttaaaaat
       61 aggtataata aattctcgtt ttaatgaatt tataacatca aaacttttat caggagctga
      121 agactgtctt ttaagacatg acgtttctcc agaaaatata gaaatagttt gggtacctgg
      181 agcttttgag attcctcttg ttgctcaaaa aatggctaaa agtggtaagt atgatgctat
      241 aatctgttta ggctgtgtta taagaggggc tacttctcat tatgattatg tatgtagtga
      301 agtctctaaa gggatagcca aagtatcttt agacagtgaa ttacctgtta tatttggaat
      361 cgtaactaca gaaaatattg aacaagctat tgaaagagca ggtacaaaag ctggaaataa
      421 aggttatgat tgtgctatga atgcgctaga aatggcaaat ttatttaagt ctttaaatta
      481 aatactaaca ttcataataa ttaaaaaccc aatatcattc actttacgat aaataagcta
      541 tttttaataa taaaaacttt taataaagct aaattatata ataaaaaaat attactggaa
      601 ttaaaaattc cagtaatata aattaattca atattatatt catataaagt atatacatac
      661 tctagtcttt caaaatggtt ttataatttt atactatttt ttatcctaaa tgttcctcag
      721 ataattccct atgccactct gatacctttt ctaggccttc tatttcatct gcaataaaca
      781 cagggtcttt tattcctgat tttttttgac ttgtataatc ttttaaagca ataaatgcat
      841 attttcctaa aagtgctatt gctattaagt ttattatcgc catcaatgcc ataaataagt
      901 ctgcaagatt ccaaactaca tctacttgag taagtgaacc aaataaaacc atacctacaa
      961 caaaaactct aaatacatta agtttagtct tacttccact cataaactcc atatttgatt
     1021 caccataata gtaattacca actatagaac taaatgcaaa caagaatata caaactgcta
     1081 taaatatatt tccaactggt cctatatgat gagttaaagc ttcttgagct aattcaattc
     1141 cagttgctcc actactacta taacctgaat ataataatac catgaatgct gtacaactac
     1201 atattattat agtatctgta aaaacaccta aagattgaat taaaccttgt tttacaggat
     1261 gagttacatg tgctgttgca gcagcattag gagcactacc catacctgct tcattagaaa
     1321 atagacctct cttcactcca gtcattacaa ctcccataaa tgtaccaatc gccattcctt
     1381 taaaatcaaa tgcactttca actatcaatg ctataacact tggtatctct gttatattca
     1441 ttacaactat agccaaagca actaatatat ataatcctgc aaatacagga actattattt
     1501 cagaaacttt tgcaactcta tgcactccac caaaaataac tattgcagtt aaaattccaa
     1561 gacctattcc catagccatt ttacttattc caaatgcatt attaaatgca agtgaaacag
     1621 tatttgcttg aactgcatta aatacaaaac cataacatat agttataagt attgagaata
     1681 aaatacccat ccatttttta tttagacctt gttccatata atacgctggt ccacctctaa
     1741 aagcttgacc atctttcact ttgtaaatct gagctaatgt actctcaaca aagcttgatg
     1801 cagaaccaat taatgctata agccacatcc aaaatacagc accaggtcct cctgctacca
     1861 ctgcaattgc tattccagct atatttccag ttccaactct tgaagatgta cttatacaaa
     1921 atgcttgaaa tgaagagatt tttccttcct tttttgcatt tttattcgct gtaccatcac
     1981 ccagaagtct aaacatttct ataaaatatc tgaattgtac aaaatttgtt ttaatagtaa
     2041 agtaaatacc aattacaact aacattataa ttaagatata cgaccataag taattgttta
     2101 catatactac tgcattgtta atactcgtta aaataccatt gaaaaaatcc attatattaa
     2161 ttacccccct atttagtttt gttttctcaa taaatcttaa aatcaaaaaa atgaataatt
     2221 ccttgttaaa aattcattaa tttaattata atatttataa aatcaaatta caaggtttaa
     2281 aatgaataat ttttttaata tattgcagtt ttatattcaa atcaaacctt tttttattgt
     2341 ttttataata tagatatatt taatatttta taattgttat tagatacaat aaattctagt
     2401 ttaaagggta tattttttcg tttgtcgttt aatattatta tcaatggaat aattttaaaa
     2461 tttatttaaa taacaaaaat tttctttaaa ttctgtcaat tttttaaaaa ctttgttaaa
     2521 taatatactt tcatacatcc attgaaaaaa caataaaaaa gtaatactat atatagtact
     2581 agcattaggc acaaaataat acaaatggag gtacttatat tatggaattt caacaaataa
     2641 tagctatatg tatattttta atagttatgg cagctattat tacagaaaag gtaaacagat
     2701 ccgtagcagc tgttggtggt gcactattaa tgataatatt caatatactt acacttgatg
     2761 aaggattaag ccatatagat ttcaatacta ttggtgtatt agttggtatg atgctatttg
     2821 tagctgttgt caaaaactcg gggttatttg aatatatagc tatctggact gcaaagaaag
     2881 ctaaaggtga cccatggaag ataatgattt gttttgctat tataacagct attttatcag
     2941 ctgtattaga taatgttaca accgtcttgc ttattggacc aatgactata gttattacac
     3001 aaatattagg acttaatcca gttccatttt taataacaca gattttagct tcaaatatag
     3061 gaggaacagc tactcttata ggagaccctc caaatattat gattggtagt gctgccaatc
     3121 ttagttttat ggattttgta ataaatttag gtcctgctgt tatagtaata cttgctataa
     3181 ctataatatg ctttagattt atttatggaa aagaacttgt tgtgaatgaa agagctaaaa
     3241 atgcaatatt aaaactagat gaaaaaaaat ctgttaaaga taaacctcta cttataaaaa
     3301 gccttatatt aatagcattc atactttttg gttttatgtt tcacagtaca atccacatag
     3361 attcttctgt tgtagcactg acaggagcat ctataatgct tttaatagga aaacaagatg
     3421 tagatgaaat tatggcaggt attgaatggt ctacaatttt attctttatg ggattatttg
     3481 tagtagttgg tggattagta gaagttggga taataaacaa attggctcaa gcattgattg
     3541 gacttacaga aggacatctt gtatttacaa tgttgttgat attatggtta tcagctatag
     3601 tctcttcttt cttagataat attccatttg ttgcaacact aattcctctt attttgacta
     3661 tgcaagctga aggtattgat gtaatgccac tatggtgggc aacatctctt ggagcttgtc
     3721 ttggaggaaa tggaacacta ataggagcat ctgctaatgt tgtactagca ggtataggta
     3781 ataaacacgg tcatcctatc tcttttaagg agtatttcaa aataggtttt ccacttatga
     3841 ttatatctat tattatatct actgtttatt taattataaa attttaaaaa atatagtata
     3901 ataatactaa aggggatgtg tatatatgaa tattaatact gttcaaggtg attcgattga
     3961 agttctttta agacagcttg gtgccacaag aatatcaaaa gtaagtagta cattatattt
     4021 tatcaagttt gatttaggag acggttggga aatatcttat acttataata ttaatgctaa
     4081 agaccaatat tttttacaga gaattgaacc atatcctatt ggtagaggtc tatttaatga
     4141 tgaatatgaa atagtatcat ttatatcaaa ggatttaaaa aaatttctaa atgctaaaaa
     4201 tagtagtaac tttaaaacat ttgttgaagt tactagaaaa gtcaattcta tcattgataa
     4261 tgtagaggaa ctatttttaa actacaatgt agatggtgat gatttaaaaa cacttaataa
     4321 agaactcaat gacatattaa atgatattga ctatatagaa aaacatacaa aaaaaatcta
     4381 aaagtagtaa acttgtaaac ttgaaatatt attaaggata ctacaaaaaa cataaaaatt
     4441 taaattttgg ttttaaaaga ataaaatcgt atttattaaa agaaaaaata gctgatgaag
     4501 tatatatttc atcagctatt ttttttaatg atgtccacat ccgtcatgtg agcaagtatg
     4561 gtctgatgga aactctacta attttccatt tttaagtaag tctaaattag cacttatagt
     4621 atcaccttct gctctgtaaa cttttattcc cattccattt aatttaatta tagctccttg
     4681 tcctattcct ccaacaacta ctgcatctac agctgtccct gacaatgctt ttaatggttg
     4741 acattttcca tgttcatgat ctaaatctcc attatctaaa gatttaactt ctccactttc
     4801 taaatcacac acaacaaaaa ttggagcaga accaaaatgt ccatatggtt tactatccaa
     4861 tcctttattc tcctctactg gtatacatac tttcattatt atttctccct tctcttacaa
     4921 cattttttta tagatttaca ttctttactg catcctagat gtattgtatt tacatcaaat
     4981 acatctataa agctttcact agaattactt aacatagaat ttataaaatc tacacatata
     5041 ttaaatgatt ctttattaat atgatataaa acatagtatc cttctttata tcctgttatt
     5101 atcccaacat cttttaatat ttttatatgt tgtgaaacag cagaatctga aatccctaga
     5161 tatttagaaa tccccttttg acatatattt ctcttggata ctaatataag tatgttaagt
     5221 ctagtttcat cactcaatgc tttaaatatt ttaaccaagt tttccataag tacctcgttt
     5281 tgattaagta attacttaat taaattatag tactcttaat tagatttttc aaccattatt
     5341 tttaaatttt ggagtatatt ataaataatt ccaattttta ctaatataac tttgagtttt
     5401 attaataaaa gtaattacat atagatttta aaatactttt attaataact taaaaataaa
     5461 aaactgtctt gaaataataa aattatttca agacagtttt ttataaatat ctttaaaaag
     5521 ttaatcaata taaatattaa gccctcttta atttatctaa atagtaaaca gcatttaaag
     5581 ctgctatttg cccttgacca gctgctttta tataagaata tggttttcca acacaatctc
     5641 cagcagcaaa gcatccatct atactagtct tcatattatt gtcaacttta atatgaatgc
     5701 catcaatctc tattccagga accaatgcac ttggagccgt actatctttt ataacgaata
     5761 ctccatcaac ttcaatgtgg ttttctttaa aagatacttt gtttacaagt ttatctccat
     5821 ctatctgtac tggtctgtca tgtataactt caatagaatc atctaggtta tctgaacttc
     5881 tcataagatt atcttttttg tacataggta taaaataagt ctttgaagtg agttcactta
     5941 aaaaatttgc ttcttcttta gattcttcat tatatcctat aactgctacc tttttatttc
     6001 tataaagtgg tgcatcacat gtagcacagt agcccacacc tcttcctaga aattcttctt
     6061 cacccttgat tggtctagta tactctaccc cagttgcaag gattacagta gtagcttcat
     6121 acatatcatt tccagacatt attgtaaagt attctcccat agcataaata ttatttattc
     6181 ttttattttc aattgaaata tccatactat ctatatgtga tttaaacttg tcttttaatt
     6241 catcaccact tatatcataa aaacctaaat aattatctat tgaaggagct ttaacaagct
     6301 tattacttaa attatcatta ccaaacatga taattgtttt atttcttatt tttgcattta
     6361 tagcagcaga caatccagct ggaccactgc cgattatagc tatatcatat ctcataatac
     6421 tcacccattt tttataaata tgattttact tgcatttcaa ttttgttctt tggcatgaat
     6481 ccaattaaag tttctactgg ttttccatct ttaaatataa tcatagttgg tactgtagat
     6541 acattgaatt gttgagctat ttctaagctc tcatctatat caacttttac aaatctagct
     6601 ttatccttca tctcttcacc taattctgca aatacaggtc ccaacatgtt acaaggtcca
     6661 caccaagttg caaagaaatc aactacaact actcccttac taccttcaac actacttcta
     6721 aattcagatg tatttataac ttttgccatt tttaaatcct cctattaaac tttattatcc
     6781 ctatataatt atactatgaa atttataaat ataaatttac ttttataagg tctttttata
     6841 ttttatacta attagtatac ccattcttca tttctaaaaa caatttttta tatttttatt
     6901 attttaactt ttttggtatt gacaattcaa atgtagttcc aatatctaca tcagaagtta
     6961 catttatatc aatagataag tttaaactaa tcatgcgagc tattgaaagt cctattccag
     7021 aaccttctaa atctttattt cttacatttt cacttctaaa aaatctatca aatataagag
     7081 gtatctcttc tttttttatg cctataccag tgtcacttat aagtaaagtt acctcatcct
     7141 ctatatcttc tttcaattct aatgctatct catcacccaa ttttgtatac ttaaaggcat
     7201 tatcaatgaa aattaatata agctgtctta atttattttt atctgttatt ataactttat
     7261 tcttcagttt agaattaaac acgaatcttt tttcctgaaa ctcagcaatg tcaatatagt
     7321 cttctgatat ttcttccaat aacttttcta agtctatttc ttctaaatta actttaacaa
     7381 tagagtcctc tttagtaaga gacaataaat cagttatcat ttttttaagt cttctagttt
     7441 ccttcattgc agtagctatt gtttcaactt catcatttac tgtactttct ggggatttta
     7501 acatactttc taattttgat gaaactattg ttattggtgt tcttaattca tgagaagcat
     7561 cttgtataaa cttagcttga tttttccatg ctgtttctat tggaattaaa gcttttctag
     7621 tgagatatac agccacaaag taagtaatta ttacagaaat taatattcca attataagaa
     7681 cagatgtaag ctgtcttaaa gaattcatct cagaatctat atttctaatt atctgtattt
     7741 ggtatctacc tacatctaca tttaattctc taaaagtata tccattttct gtgtatttaa
     7801 aaaacgaatt ttttttatct agtcttctat ctggaagtaa ctcatcaaaa tattcatttt
     7861 gagtatagta acttatcctt ccatcttcat atacatacac catatcttta ggatctttga
     7921 gtcttattgg gttcaaaaat gaagttcttt taaattgaga gactatatat tcaagttcat
     7981 catttatctc actatcaatt ccactatatg taagtcccct aaaatatgag tatataaata
     8041 tagaaaagat tattaaaaaa ctacctacta caataatata catttttatt aaatgatttt
     8101 tagtactggt aaatacattc ttatttatca tcgaatatat atcctacctt acgtttagtt
     8161 ttaatatatt tatcatatcc atatttactt agtttttttc ttagattact tacatatact
     8221 tccactattt caatagtcgc atctgaatca attccccata ttctatcata aatctgctct
     8281 tttaataaaa ttgaaccttt atttaataca aaatactcaa gcaagttaaa ctgtttgttt
     8341 tgaagtttta tttcttcttt ttcaatatac actctttttt ctagtgtatc taaatataaa
     8401 gatttaaatt ctaatccgtt tctttctttt atttttccat tagtccttaa tatagcgtat
     8461 accctagcta ctaactcttc catataaaaa ggttttgtca aataatcatt agctcctata
     8521 gtaaatgctt ctactttgtc atctaatgtt tcttttgctg tcaatataag tacaggtgta
     8581 tctatattat taactctcat tttctttagg atatcaaatc catttatatt aggaagcatt
     8641 aagtctaaaa tgactaaatc atatatattt tgatttacta agtataaagc ttcttctcca
     8701 tcttcacact tttcagtttc aaaatgcttg ctaagttctt ctactacact ttctaaaagt
     8761 atcttattat cttcaactat taaaaccttc ataagtatcc cctaccttta tttgtctatc
     8821 ttaactttat gagattttaa gtcaatatcc acattggctt tttcttttat atcatcatac
     8881 gtatatccca ctatttcaac actttttgcc tttgttgaac acaatatatc tatatctgtc
     8941 tcttctgaag gctttaaaat cttatatgat ggcacacgat ttactgttaa atattctcca
     9001 ttttcattaa cttctgctgt cttaagaata atatttccta aatcttttga tgatgaattt
     9061 tttactttta cttgatacgt aattccctca tttgattcat ttactttttt aagttctgat
     9121 gtagatagca cctcatactg actactattt tctagcttaa tattattatt tcttatatta
     9181 atagtatttt cttttaaatt aacatacaca atcttaccct ctgcctcata ttcatatgca
     9241 taaacttcta caccctttac aaaagtttta tgcccacatt ctatgtaagc aactttccca
     9301 ggcattaaag tcatgtccaa caaagcctta ctatccgaag atataatttt tttattctca
     9361 tcatattcat tatatatcaa ttcaacattg gatatattaa atgttgaatt attttctacc
     9421 tttgttgatg tatctacttt atcaccttca tctatattta taatttctga ttttcctata
     9481 ttcaatactt ttgcatttcc ctcatctatt tttatctcat ttttatcttc tgtttgaata
     9541 tcaactgaat caggctgttc atctttttca catgctgtca acataaaaat aaatattgtt
     9601 aatataatca ttagagaaat tgattttttt actattttat tcatattaag cacctcatat
     9661 agtagtattt tatagtagat ttttatactt tttcataaat tctttcaatg cctgtgtaag
     9721 tatttgatgt ttttcaaaat tcgaattact acataatctt tcaaaatcat tccatatttc
     9781 tttatctata cgtattcttg ttgtttttaa ttcatctatg tgttcatcat ctatatgtac
     9841 atctttttta ttagatactt ttttaggctt tatattgtaa tcttttactt ctaaatacca
     9901 atcatatact tcacaaagct tatctaaatc ttcttgagtt atatttattt ttctatcttt
     9961 cttaggctta acattttgtt ttggctttgc attttttaaa cctgtatcat taaactcaat
    10021 ttgttcaaca cttttactta aagccttttc attagaaatc ttttttttgg tgcttacttt
    10081 ttttctatta cttatagtat tctttttact tttttcatac tccttagctt tctcttcttc
    10141 caagtttcta ttatccaaac ttttattata atttaattcg tcttttaata tgtatttacc
    10201 tttttctgac ttatatcctt ttttatttaa aaaagttctt aaagtacttt gactaatctt
    10261 tagattttga gctatctctg caaatttaaa tcctttgctt tgaagttcta aaaatttgtc
    10321 aattctgtct tcattgttat tcattaatat tcctccgtca acatcttctt gtctttcttt
    10381 tcatacttct tattatattc ttcttttcta aatctactct atttgattca attatttttt
    10441 gtagcatttt attataagtg aaatcatcta aattattatt ttttatatag agaaaagttt
    10501 cctcttcaca tttaataaaa caaattgata gcaaccatgc catacccatt ttaacataat
    10561 attcttcact ttgtatatta ttacagtatt caaatatttc tttaatatgt ttatcatcaa
    10621 cataatatat taaaaacata actaatgcaa atctaatttc ccatggattc tttgaataaa
    10681 catatttttt aagtatatca tacatatttt ctttatattt tttcatagac tttaaatcag
    10741 aacaaaatcc atcgcaaact gaccaattat cgattttagg tataaatctt tttacatagt
    10801 ataaagtttc ttcaaaatta ctatttatat tgccaattac cataccttgt agcctaactt
    10861 cttcatagta tgtatcctct gctacttcta aaaattcctt ccaatttcct tggcttattt
    10921 cttttgataa ctttcttaaa ttaggaactc taatacctat tatattttct gttccaggta
    10981 taagcttttt attaaaatct ctatatttta tatcttgtat agacatcata tattctaaaa
    11041 gttcattata atccaattta ttccattttc ccctatcaaa catcatttaa ttgctcctta
    11101 attccttttt tcttattgta acataaaact ctacaaaaaa agcttctaac tattagaagc
    11161 tttttcaaaa acataagaaa cttttcaatt ttaaatttaa actaaattaa tgctaatctc
    11221 ctacaccaaa gtctgtatta ttgtataaaa cttctatatt tggattttca tccaagaatt
    11281 tatacttact aacaaaccat ttcactaact cttcatctct ttttatacta gaagaattat
    11341 ttataaaaac attcactgtc gctttttcaa aagtatttag gataatctct atatctttat
    11401 ctatcatctc ttttgtttgt ccttttattc caaccataat acaaggtgaa tcaaaatatt
    11461 cttttacatc ttgtggagtc ttaaaatttg catttttatt taaaatatta tttctaaaat
    11521 aattgtcaaa ggtttcaact ccaattttaa ataccacagg aatttcaaaa tactctctca
    11581 tttccttaag cctatttttg taagaccaat gactttctaa aaataatttt tttatatttt
    11641 tctcttttat aatacacttt attttttcta aagtatcctt aggtaattca aaacagcttc
    11701 cagaatttat gacttcaaga actccatatt tcccagttac gttttttaaa acctttagat
    11761 ttaatttatt catctcttct tctaaattag aattatcatc tatataatca caaaaagaac
    11821 actttcccca tatacaagga aatcctttaa gcagaacaat ttctctttga tttttatttg
    11881 ttatctcact atatctatcc attttctatc tattttcctc cagtcaatga tacctttaaa
    11941 gtttttggaa ctgcatttaa tcctaaattc actaaaacaa ctgctaacag cttatctcca
    12001 taatcagtaa atacttgggt tacaaacaca ctaaaaacat ctcccagtcc taacactttc
    12061 aagatttgca ctatatatga tgaacctgaa gaggtcatac ctccaaataa aaatgctgaa
    12121 attattgaac ttattataga tgttggaatg gcaaataaaa gtactcctat tggagttttt
    12181 aaacccctta aaaaattctt tttaaatgct attccagcaa gtaatccggt tgatatttga
    12241 actggtgcaa aatagagaga atacacatca aacgtaattc cacttattaa acttccaaac
    12301 acacctgtaa caacagcgta tttaggtcct aaaagtgaag ctatcattat agttcctatt
    12361 gaatctaagt atacaggtaa tcttaatccc atagctataa aagcgcctat tatatttata
    12421 gaaataccaa aagctataag tgtaatagtt tttacacata tttttctttt cacactatat
    12481 cactccttcc acagagtcta taatgttttc ataaccttta aaaagcctct ttaaaaacat
    12541 gtacataaat ttcttctcat caacttcatt tagaacaatt gcattaggat tttttttata
    12601 gaaattgaaa gaatccacta tagactgacc catagctatt ccatcttcta caacttctac
    12661 atatgattca aatcctttac atatacttct atctataaag tatgctactg ctagagggtc
    12721 atttatcaca cagccaatta ttccctcctg ttcccaatgg aaatcaatat aaaatctagt
    12781 tatttcagtt atatactttg ccatcttctt atcaagtcta tttataaact caataatatt
    12841 aggagtaagt acaatttttc tagttacatc taaacctacc atgtggattt ttttagataa
    12901 attcttgtaa acataatctg ctccatgtgg gtctacccaa taattaaact ctgctactgg
    12961 agagcaattt ccatgaatcc taaatgctcc tcccatagat acaaactcat cgagattttc
    13021 aaatgctttc ttatctttaa taagtgcttt agctatattt gtaagtggtg caagtgctat
    13081 tattgatact ttttcatgat tatgtaaagt atttattata aaatccactg ctccattttt
    13141 tgctttagct cctacaacct tttgataaaa gttttctcca ataccatctt ctccatgtgt
    13201 atcttgagct gttacaagtt ttctttttag tggtgcttct tctcctatat atactggaat
    13261 atttagtgaa gaacacattt gaagtgtttt tagtgcattt tctgcaccta tatttgctgg
    13321 aacatttcca caacatgtgg taattccaat tacttctagc tctggtgagt ttaaagccag
    13381 aagaattgcc aaagaatcat caattcctgg gtcacaatca attattactt ttctcttttc
    13441 cattttttat cctccttgat ttgtggtcga ggagaactac acatcttttt tccactttca
    13501 aaaaggtgtg tctaagggta ttaattatat actgccacta tataattcct tagtttttta
    13561 tacttggagt tctcgaacaa gtacagatgt aaaatcatat ttttaggcta cttactatag
    13621 actcttaaaa actatagact gttaaaaaat ttttaaacat ctgatttaat agctataaaa
    13681 taaattttat agcataaaag aatttattat attttaatgt atcttattaa agtttattta
    13741 gaattatgaa ccaactttaa taagatgtgg cgcatttaaa ccgattatta ttatacaata
    13801 atatcttaaa tattacaatt aataacatta atttattatc cataaaaata tattaactta
    13861 tattatttaa taatttattg acagtattaa aattaaatta tacaataaca gtgtaaatta
    13921 acttaacacc gttaagcaaa gaggtgatta tatgagtatc aaagaaagac gtaaaaatga
    13981 aaaagaagaa atgaagaaaa agattatgga tgctagcatc gaaattataa accaacatgg
    14041 atatgaaaat ttatcaataa gaaaaattgc tacaaaaata gaatattctc caactacaat
    14101 ttatctttac tacaaagaca aagcagaaat tatcagcgat atgaccaata aactttataa
    14161 cacagtagaa agtaatgcta ttgacattat gaataattgc tcatcactac caatagataa
    14221 acaaatcata gaaattatga ctagctttat aaaaactctt tctagtgaac cagagatggc
    14281 aaaatctatc atgcatagta gaatgaatat tatatttgca tctgaaaata caaacaatac
    14341 gcctagcaat aatggtataa aaatgcttga taaattcctt tccattggaa ttgaacaagg
    14401 aatattcaaa aaaaatatag ataaaagctc atggatgctt ataagtgcat tgttaggatt
    14461 cgttttatgt gttgttgaaa ataaactata ttctttacat aatttttctc aacttataga
    14521 aaatttctta gatattttag tgggaggact ttacaatgaa aattcgcaac aaggctacta
    14581 ataaaaagaa aaaatatgta aaaatatcta ttgctctatt ctttgtattt atatgcatta
    14641 ttattgtaat tgtaagcaac ttaaagccag aaaacttggt agtaaaagat atagatatta
    14701 ataatgttaa aaatggcatt tatactggaa gtgctgataa taacttggta aaagctactg
    14761 tgtctgttga agttaataat ggtaaaatcc aaaatattaa tatcttaaaa cacgaccatc
    14821 ttttaggtaa acctgctgaa aaaattacaa caagtattat taaacaacag tctttagatg
    14881 tggatgctat aacttctgca acttatagca gtaatactat acgaaaagct gtagaaaatg
    14941 ctttaagaaa gggagaataa ttatgaatac tattattata tattcaagta aatatggttg
    15001 tacaaaagac tgtgcaaata tactaaaaaa taaactatca gataatgtca ctattgttga
    15061 tattaataat aataataata aaattgagtt atcaaaattt gataaaatta ttattggaag
    15121 ttctatatat gttggttcag tttcaaaaaa aatacaagtg ctatgtaatg ataatgtaga
    15181 gttattaaac aaaaaacaag ttggcatttt cctttgctgt ggcttttctg aacaagcaga
    15241 taaatattta aaatcaaatt ttccatcatc cttattagaa agtgcaaatg ctattggaat
    15301 ttttggtagt gaagctcgat tagaaaaaat gaaattttta gataaactta ttatgaaggc
    15361 tgtttcaaaa ggtaattatg acagttttag aatatcacag gataatatag ataatttttt
    15421 aataaatctt aatagctaaa ataaagctaa ttatttctat gataaattct tttatttata
    15481 agtaatattg ctcaaaatag tctttaaact ttatcaaaat tttatttttc ttagtgaaat
    15541 ctaatgaaac tatcacttaa tatatgcttt attaatcata acaaaaagag agtgtctaat
    15601 gaactaaaaa attcattaga cactctcttt ttgtatgaaa tcaaatatat ttttatcatt
    15661 tcaaaagtga aaaatacact tgtctctatg tttggcacat tctcttttta taatataata
    15721 tctaatttaa aacctatttc aaatattgac atatacttaa actatagact tacaaaatca
    15781 attcatatta gcttaaaata taatctttgt tattcaaatt cctatacaca accattattt
    15841 actttgatac tttaaaacat cttccctatt ttttattaaa ttttataata atagtcctat
    15901 taacgcaaat actataaaaa gagtttaact ttatccatta aataaattta aattaaaaca
    15961 tatagaaatg gaaggagaac aatttatgat aaaactaatc ggtatattga tagttataat
    16021 tggatttata cttaaaattg acacattatt tactgtatta ttagcaggag tggcaacagg
    16081 aattgttgca ggattagatt ttaatcaaat ttttacaatt ttaggagatt cttttgtctc
    16141 aaacagaggt gtatcattat tcatattaac attgccagta atcggtgtat tagaaagata
    16201 tggtttaaaa caaagagctg tttctttaat agaaaaatta aaaagactta caacaggaaa
    16261 agtacttact atatacatga tagctagaca aatagctggt gctctatcaa taagaatgag
    16321 tggacatcct caatttgtaa gaccacttgt taatcctatg gcacaagctg ctggtttaag
    16381 taatagtgat gagctaaaag aatcggatga agaagccata aaggcattat ctgctgcatc
    16441 agaaaactat ggaaattttt atggtcaaaa cttatttgca ggtagtagtg gagtattact
    16501 tatagcatct actctgactc aatttggata caatgtaact ggacttaata ttgtaaaggc
    16561 tagtactatt atggcagtaa tagcacttgt agtggctaca atccagttta ccttatatga
    16621 taaaaaatta aacaaaagtc ataaaaaata gttttattta ggaggaataa aaatgcaaaa
    16681 ttttataaac atatcattag aaatctttta cgcactaatg ggatttttaa tgattgttat
    16741 agcatataag tcttttacta ccataaataa caataagaaa tatggtacat cattattttg
    16801 gatacttata tcactgccat tcatatttgg tagattgatt ccagccaata taataggaat
    16861 aatattaata ttatctagtt tattaacact ttctaaacaa gttgtatttg caaagtatga
    16921 agaaccagat gaaaattttg gaaaagaaca agcagacaaa cttaaaaata aaatatttat
    16981 accatcatta atattagcat ttgctgcagt agtagtagct atgagccttt ctaattttga
    17041 taattcttct caatttgcaa taggtgtggg ttcaataatt gcattaatat cagcccttat
    17101 aataactaag gcaaaatctg ctacatcagt tcaagatggc tcaagattac ttcaacaaat
    17161 gggacctgct agtatgttac cacaactttt agttgcactg ggagctttat ttactcaagc
    17221 cggagtcggt gaagttattt caaccatgat atctggtgta gtccctgctg atagcagatt
    17281 atttggtgtt atagcttatg tattaggtat ggttatattt accatgataa tgggaaatgc
    17341 atttgccgca ttttcagtca taacggcagg aattggtatt ccttttgtat tgtctcaagg
    17401 tggaaatcct gctataattg gagcattagc attaacagca ggatattgtg gaactctact
    17461 tactccaatg gctgctaatt ttaatatagt tccagcagcc ttgctagaat gtaaaaatga
    17521 ttatattgtt ataaaatatc aagctccagt tgctttggta ttaattatag cccacatatt
    17581 agtaatgtac tttttaggat tttaatataa ttaggaggta aaataatgaa aattttgtta
    17641 acaggatttg acccatttgg tggagaacca ataaacccag ctcaagaagc agttgaaagg
    17701 gtcaataata atataaacgg tgcagaaatc ataaagataa ctataccaac agttatgaca
    17761 aaatctgttg aagctataga taaagctatt caagagcaca atccagatat agtaatatca
    17821 gttggacaag ctggaggtag atttgacatt acacctgaga gagttgctat aaatatagat
    17881 gattttagaa taaaagataa tgagggtaac caggttatag atactattat aaaagaagat
    17941 ggtgaacctg catatttttc aaaattgcct gtaaaagcta tggtaaaaca tatgaatgaa
    18001 aataaaattc cagctagtgt ttcaaacact gcaggaacat ttgtttgcaa tcatgtgatg
    18061 tatggaattc tttatatgat agacaagaaa tatcctaata taaggggtgg atttatacac
    18121 atcccatata caacttcaca agtaatagat aaaaaaaata caccattcat gtctttagaa
    18181 gaaatagtaa aaggcttaga attagctata gaagcttgta ttatatataa agaagatgta
    18241 aaagaaattg gtggtgaaat ttcataataa attttttagt atttttataa attaaaaata
    18301 ctaactatta atttaaatat agactgtgag tagattattc aaacaatttt actcacagtc
    18361 tttttatggt atctacagat acaaaattaa ggtctattcc tctctcccca ctcacacatt
    18421 gcatctaaaa ttggaatcag agattttccc ctttctgata gactatattc taccttagga
    18481 ggtatttgag gatattcagt acgaataatc aagttatctg cttctaattc ttttaatgat
    18541 aaactcaaag ttttatagga gatagtattt atataacgtt ttaatgcatt atatcttaca
    18601 acttcaaatt ctacaagaca gtaaagaatt atcatcttat atttaccact aatcagtgaa
    18661 agtgtataac taaatcctgt ttcacttaaa tctgtatttg atatacagtc tatactcata
    18721 tattacactc tccttttggt tagtattgaa caaaaatgtg cgtacttgtt tttagaataa
    18781 tttataataa aattatagtg taagaataat tgaaagtcaa ttttataata ggaggtgtat
    18841 ttactaaaaa aaagttattt taaataggat tctaagatta gacatttcta tataaattga
    18901 taatattcat gaaaatccta ttttataaaa aataatatct cttagaaaat ctattaaata
    18961 aaattcatgg gaggaaattt ataatgaaag ttttattgat aaacggtagc ccaaaccaat
    19021 atggatgtac ttatacagca ctaaatgaga ttactaaagt attgagtaaa cacgatatta
    19081 aaacagaaat actgtattta ggtaaagaaa caatcacagg atgtattagt tgcgcatcct
    19141 gttttgaaac tggaaaatgt attcgaaatg ataaagttaa tgaattgatt gaagatctgg
    19201 ataatattga tggtattatt attggttctc ctgtttactt ttctagtgca actggtcaat
    19261 taacttcttt tcttgaccgt ctatttttca tagctggaag tcgcatggct acaaaattag
    19321 gtgcttcagt tgtgtcatgt agacgtggtg gtgcaagtgc aacatttgac caactaaata
    19381 aatatttttc aatcagcaat atgcctattg tatcatcaca gtattggaat caggtacatg
    19441 gctttactcc agaggatgtt atgaaggatg aagaaggatt acagactatg cgaactctag
    19501 gagaaaatat ggcatggctt cttaagtgta tatcagcagg taaaaaaact ggaattaaag
    19561 aaccacaata tgaagaaata attatgacta attttataaa ataaataaaa aatgtactaa
    19621 tattaattaa aacaaaacac taatttataa ataaaataag cataaatgta ggataaaaag
    19681 cactaaaaca gaggtattga attttatatc aaacctctgt tttattatta cattaataac
    19741 caaaccatgt ataacatcat atatttctaa ataaattata atattatatt ctaatgttat
    19801 tgaaattaca ataactgaat ttctgctcat aaatttaaat attctacaaa tctcatctaa
    19861 ataacaattt taatagacct aaaacaatcc tcatattgtt cattttgtat taaaaatatc
    19921 acttacaatc aaaaaccatt tattaagtat attcctaaga tatacaatat atatacatgg
    19981 attggatagt ataaataaaa taaatacttc atactcttcc ctttttctcc attgtaaagt
    20041 aacattaaag gtagagaagc aatcatcatc cattggtaat tttgtaaaat agaatttttt
    20101 aaactataat ctccatttga cattgttgta aatataaata tacacattaa agcataacaa
    20161 atactcaaac tgaacttttt ccctctacac aaataaaaaa taatcccaag tataatccaa
    20221 attggtccac cttctactaa aaatggtact ggtaccaaaa tcataaataa agcaataact
    20281 ctgttagtga ctttaaaaag taaagctact gtaaatattc ctaaaattat aggaatgatt
    20341 atcatcaata atcctataat aaaatattta atttctttct cttttctaaa tttctttatg
    20401 aactctattg cttgtaaata aatcgctatt aaaaataatg ttgaaaaaat gttatttata
    20461 attatagctc cttctggatg tgaaaataca ttattaatta tttgatttcc tatagccata
    20521 ataacagacc aaatatacaa tctacttata tatttttttc tgttactagt gtgataaaat
    20581 ccttcaacag ccataaatat aaacagtggt gctgatattc tgcctaccca atgaaaccaa
    20641 attggtattt gcattgtttg tggcataaat gctgctatat ggtcaaatgt cataaatatt
    20701 aatgctaaaa tcttaatagt aaacccactt ataccttttt taaaaaaatc catatcatat
    20761 ctcctaattt tgttttatct ctataataat ttttgttcct attccaattt cactacttac
    20821 ataaatttta cctttatgaa tctctattat ttctttagaa atagccatac caagacctga
    20881 acctttatgc atctcacctg tattagtacc tctataatat tttttaaaaa tatgtttcaa
    20941 atcacttttg cttattccaa ttccattatc ttttattata atttctatat tatctttttt
    21001 tacaatttct acacttatca aagttccttc gctattatga actattgaat taaatataag
    21061 attggttata gcccttctga ataagattga atctacatat acttcaatta aatcttcatt
    21121 actttcaaat tcaatattcc tatttttata tctattatca tttaaaatat caattattgt
    21181 atttctgact aaactgacta aatttatttt tttcttgtcc agaactatag tattattttt
    21241 taatcgagta gataaattta aatcatcaac taaatctttt atatacttag acttattata
    21301 tataatttct gtatactctc gtatttcatc ttcttcaaac tcataatctt tgtcattaat
    21361 tatctctgca tacccttgta tagatgctag aggtgtcttt atatcatgtg ttatatttgc
    21421 cagccattcc tctctcaact cttcattttc ttttctctca acttcattta ctcttaaagt
    21481 atcagctaac atatttatat ttttaaaaac ttcttcatat atacctctgt ccttaagata
    21541 taaactataa tttccattag ccatagtctc aatactccat agtacgcttg aaattggttt
    21601 tgtaagtttt ctactaaata aatatcctac gcctaaagct accacgctat caattactag
    21661 tgttataatg ataactttat ttaaagtttt tttaatgtta ttttgagaat aggttaaaat
    21721 tattcttgat atatctctac taggtatacc tactattatg tttagatgtt ttttgtttaa
    21781 atatttttct agtacaaaat taacatactt tgtttctata tacttgtaat tattcaccat
    21841 ttgaaagggt gtatattttt tgggagtatc ctttggcaca tttactccat aaacttcctc
    21901 tcctaaatca tttaaaacct gtatccagga atttgatttt tctaattttt cagctccaat
    21961 cttagatagt ttaaattctc catctttttc atataaatct ttttcaaaag aacgtgcaaa
    22021 ttcttcagga ttatttccag aatctacaac tttaaaaaaa ctattagttg aaatcacata
    22081 caatatagat atgatattta taattactac tgatatagct acaaacacaa ttgtaaatat
    22141 aaaatttcta gtaatcttcc acttcatatt ctaatcttcc tttactgcta atttatatcc
    22201 aagacctttt attgtcagaa tatattcagg ctttgaagga ttatcctcta atttttccct
    22261 aatttttctt atatgaacca ttatagtatt gtcaaatcca acataatctt ctccccacac
    22321 tttatcccat agtttttctt tacttataat ttgattttga ttatgtgcaa ataaagatag
    22381 gatttttagt tcctttgcag acagtcctat agattttcca tcttttataa gttctgccct
    22441 actttcattt aatatatatg ggccaaatga tataattttt tcttcattat tatttagatt
    22501 tttactttcg ttttgagcat cactaaaata acttaatctt ctcaaatgcg ctttaactct
    22561 aaaagccact tccttagggc taaaaggttt tgtaacataa tcatctcctc caatcgctag
    22621 tccaagtaac ttatctaatt cttcggtttt agctgataaa aatattattg gagaattgga
    22681 ggtttttctt atttctttac aaatatcata accttcgcca tctggtaaca taatatccaa
    22741 tacaatcaaa tcaggattaa tacttttaaa taattctaat ccttcttttt tagtttttgc
    22801 agtatatata ttattaaggc cctctttttt taggacagtt tctaaaagct tcaatatttc
    22861 tacttcatca tctattatta aaacacgatt ttccataaac aacctcctgt aataatttac
    22921 atatatatta gcatatattt tatctaaaat tcatttatct tatttttaat taaactaaaa
    22981 tataaataaa attactatta tttttagtta aaaccttttg cttgatgtaa aattttcata
    23041 tgttatttta gttaacacta tcattaatat aattgagatt gctatagaaa aaactatcaa
    23101 aatacttggt acattatact taaccatttg ttggctcatc ataatccaat ttggagtcac
    23161 tgacataaat tttatagctt tatctggtat aaaacctaca ctaaagtatg gaattgccat
    23221 tatcaatcca cctagtataa atggaattac agccgattta aatatagatg aaagtgttaa
    23281 gcctatttgt gcaaatataa aagaagcaaa aatagtagtc aatataacaa ttatatacat
    23341 ttgtattact gtaagattta aattactatt tccaaagtac cataagttat gaatcggttc
    23401 atttaaattt ttaaaatcaa aaaaactaaa acctctaatt cctactaaca atataaaaga
    23461 aatattaata atagataaaa ttaatccatt agctactagt tttgataata ctactgattt
    23521 ttttcccttt ttagttgtat ttattaaacc tgtcatatta gaatcatatt ctttaatgta
    23581 atttccagaa gttattataa acattatcaa acctattaga ggtattgagc cttctatctt
    23641 gtaaaatata tctgcataag tatctaaaac atcaaacttt ctaatcagaa aaaatccaaa
    23701 aaatattaaa aacagccaaa ttatccaaac actctttgat tttaatattt ttatcatttc
    23761 agctttaact aaatacatca tttctactac acctcccttg catcttccaa atcaaaataa
    23821 aacatgtata catcttcgaa ttttgcttga actggttgta tattatcccc acttggaata
    23881 tcctctgaaa caattctaag tactactgaa tcaatatcac tttgaatact tacaacctta
    23941 tatttagatt gtatatcatc aacttcacat tcatttttaa cttgaacatt atatacttta
    24001 ttttccatgt gacttaatat gtctttgtgt gttcctttca ttagaagttt gccatcttta
    24061 atcattattg tttcctttgc aactgattct atatcggaaa ttatatgagt agaaagtatt
    24121 attatcttat ctctagacat ttttgctatt aaattcctaa atctagctct ttcttgtggg
    24181 tcaagacctg ctgttggttc atcaaggact attatcttag ggtcgtttag taaaacttgt
    24241 gctatcccaa ctctcctctt catacctcct gaaaattttc ctatagactt atttctcaca
    24301 tcataaagac ctactaaatc taataattct cctatcttac tatttaaata ttttcccctt
    24361 aaacctttta aagctccaat atactgtaaa aattcttttg ctgtaaaatt tttataaact
    24421 ccaaattctt gtggcaaata tcctaaaata tttctataat cagcatccat tttaaatata
    24481 tcctcaccat tataaagtat ctgaccttca tcaggtttta tcaacgttgt tatttgtttc
    24541 attaatgtag attttcctgc tccatttggt cctagaagac cataaactcc attttccaga
    24601 gttactgtaa tcttgtcgtt tgctactttt ttaccatata tctttgaaag attttctatt
    24661 tctaatttat tcatcttaac tcccctttta tctacttata taatctgatt ttattactaa
    24721 aaaacataat gacatagcac ctatcaatat tgccatcaaa agtcctattg ctatattgac
    24781 aatgtctata ttcactttaa atatcataat atcacctaga taatttccta ttattttatt
    24841 aaaaccaaat atcaaatcat aataatttac atttgataca actgaaagta attttttagg
    24901 taatatatgg attaccgaca ttatcttagt tatagatata ataaatataa aaaaacttat
    24961 tgaagatatt gaagacttac ttataaaaga cccaaatatg gctatcatgg cccatccttc
    25021 aaacatcaaa agctctatgc ctatatttaa tattacatac tttgttatac ttaaattagt
    25081 tttcaatgca actacattgt ctactattct aaaagattct aagtctccat taacaggtac
    25141 tccttgttgc atacaagtta taataaatat tcccattaaa taaacagaat aaattactaa
    25201 tggaactaat aaagcaacaa atattttaga ctttaatgct tttttcttct cttttgatga
    25261 tagtatgata tcttttaccg aagtaacgac ttcatctacg taaatattgg atataattat
    25321 agatataatg attaacattc ctacatttat aagtgaattt gtaactctat agttaaatac
    25381 tttccaaaaa ctaatatcct tatattcatt cacacttaga ttatcaagtt ttttctttga
    25441 cattaattca atttttttag aaaattcacc tgtatctgtt tgatttgaaa actgctttaa
    25501 aacattaatc ttattttgaa atttctcatt acctatgtcg ataccacttc tcgtatcttc
    25561 tatacgtcct ttttctttat ctatataata actttctgtt tctaaaacag gcgtaataaa
    25621 gatactaatc attagtatta acactaatat ccctagagat ataaacatac tcttagattt
    25681 agccaatttt ttatttccca atttaccaat atatttctcc tcctaaatca ttttaattac
    25741 acatatatat taaaacttaa atcttatata aatataatac taaccttaaa taaagcttaa
    25801 attattttat aatttatagg tgtgtttatt attggagtta catttattat ttttctggga
    25861 aattatacat tttcaattat ttttattatt tttgatattt ttattgattg gaaattttat
    25921 tgttgttcaa attgtagtta ttctttaaat ttaaagatgg agttttttaa gaatagaacc
    25981 tactgtcctt attatggaaa gattattaaa tagttgcata taactttatt tatcttgaat
    26041 cttattttta aaaacaatta taattttaga atattttcta ttctcaaaca agcatgttga
    26101 ataatgaagc atcttctagt attatatact tgtagaataa aactaaattg gtaaaactgg
    26161 gaatatttaa ccttaaggag ttaagttata gaaactagta ctaaaaaatt ttataaatta
    26221 tgttaattga ctaatagaat gcgacttttt atttttacta aattttttag ggggatggat
    26281 aatatgttta ttggagaaat agacaaatgt acacatatac taactgctta catcagtagt
    26341 tcatatgatt attgtaattt tttagataca cagttagatg attttatatc agaatatgga
    26401 gaaacggtag ttgaaacctg cttacatcaa gtcttattat tagtaagtag atacaattaa
    26461 aactaaattt ttctagaaaa acctttttag atttatctac tctaataaat atataatttt
    26521 ttgtacttta taaataacta taacttctgc taaagtaaag atgtattggg agtacatctt
    26581 tactttccca ttatagaagt taaaagcata caccataaaa ttaatcatcc aatacaaatt
    26641 atatatttcc tatgtctaac ttaatttaca agaatcattc tatatgcata ttctgcaatc
    26701 cactaaacat ggctctaaac ctttactatt ttatacattc tctataaatc atacaaatca
    26761 tatataaaat ccccctaata tgtttaaacc acctataaaa taacaccaat atttagaata
    26821 ttcaatatca actgcataac tggtcaataa aaacgtataa ctagacaaat ttcaatattt
    26881 atataaataa tacaagaaaa acaagcattt tatttatata agttttttat tttttgttta
    26941 tattaaaaaa ctatattgat
//
LOCUS       DAEPUT010000055        26382 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.057, whole genome shotgun sequence.
ACCESSION   DAEPUT010000055 DAEPUT010000000
VERSION     DAEPUT010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26382
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.057"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            297..740
                     /locus_tag="KRL22_002475"
     CDS             297..740
                     /locus_tag="KRL22_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1272952.1"
                     /translation="MIEIKTIEINKKSQIDLLILADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            912..1082
                     /locus_tag="KRL22_002476"
     CDS             912..1082
                     /locus_tag="KRL22_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272953.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            1455..2564
                     /locus_tag="KRL22_002477"
     CDS             1455..2564
                     /locus_tag="KRL22_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH1272954.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIEKGIAKGKREEKF
                     NIIIKLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            2769..3257
                     /locus_tag="KRL22_002478"
     CDS             2769..3257
                     /locus_tag="KRL22_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HBH1272955.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     IAVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            3343..3750
                     /locus_tag="KRL22_002479"
     CDS             3343..3750
                     /locus_tag="KRL22_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272956.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            3751..3969
                     /locus_tag="KRL22_002480"
     CDS             3751..3969
                     /locus_tag="KRL22_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272957.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTIVEELFEFIEENNI"
     gene            4785..5080
                     /locus_tag="KRL22_002481"
                     /pseudo
     CDS             4785..5080
                     /locus_tag="KRL22_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5488..6177
                     /locus_tag="KRL22_002482"
     CDS             5488..6177
                     /locus_tag="KRL22_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1272958.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIRYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            6177..7094
                     /locus_tag="KRL22_002483"
     CDS             6177..7094
                     /locus_tag="KRL22_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1272959.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLVEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            7167..8093
                     /locus_tag="KRL22_002484"
     CDS             7167..8093
                     /locus_tag="KRL22_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272960.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFSKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVEFAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            8090..8770
                     /locus_tag="KRL22_002485"
     CDS             8090..8770
                     /locus_tag="KRL22_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272961.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIIGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            8871..9203
                     /locus_tag="KRL22_002486"
                     /pseudo
     CDS             8871..9203
                     /locus_tag="KRL22_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
     gene            10307..10957
                     /locus_tag="KRL22_002487"
     CDS             10307..10957
                     /locus_tag="KRL22_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1272962.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            11252..13318
                     /locus_tag="KRL22_002488"
     CDS             11252..13318
                     /locus_tag="KRL22_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH1272963.1"
                     /translation="MKEVVESLKKITKERIENTMKKLFTSETFLEYQFISDCQISPNG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKDAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLVIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQRLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            13335..15290
                     /locus_tag="KRL22_002489"
     CDS             13335..15290
                     /locus_tag="KRL22_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH1272964.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKSGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGIDISSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAASQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            15306..16496
                     /locus_tag="KRL22_002490"
     CDS             15306..16496
                     /locus_tag="KRL22_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH1272965.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            17646..18020
                     /locus_tag="KRL22_002491"
     CDS             17646..18020
                     /locus_tag="KRL22_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1272966.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYEED"
     gene            18022..18879
                     /locus_tag="KRL22_002492"
     CDS             18022..18879
                     /locus_tag="KRL22_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272967.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            18882..19520
                     /locus_tag="KRL22_002493"
     CDS             18882..19520
                     /locus_tag="KRL22_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH1272968.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVMIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            20539..21273
                     /locus_tag="KRL22_002494"
     CDS             20539..21273
                     /locus_tag="KRL22_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1272969.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            22733..23989
                     /locus_tag="KRL22_002495"
     CDS             22733..23989
                     /locus_tag="KRL22_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH1272970.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASSVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            24052..25245
                     /locus_tag="KRL22_002496"
     CDS             24052..25245
                     /locus_tag="KRL22_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH1272971.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIAGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGESK"
     gene            25446..25826
                     /locus_tag="KRL22_002497"
     CDS             25446..25826
                     /locus_tag="KRL22_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1272972.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
BASE COUNT        10115 a         2738 c         4422 g         9107 t
ORIGIN      
        1 tagtattata gatgaatatt agtattgata ttctaggtaa ctgctagagc taatattata
       61 gatgaatatt agtattgata ttctaggtaa ctgctagagc taatattgta gatgaatatt
      121 agtattgata ttctaggtaa ttgctagaga tgatattata atttattatt aatattaata
      181 ttctagggaa ttatcactat attttaaaaa gtaaaaatat atatcaaaat gaactaaata
      241 agtactgtaa gaagtttgtt aaattaaggt ttgaataaag tgagggtgga gaacttatga
      301 tagaaataaa aactatagaa ataaataaaa aaagtcaaat tgaccttttg atattagctg
      361 acccatgtga agaaatgatt gataaatatc tcaataaagg aactatgtac gcattgtatg
      421 ataataaaga acttacttgt atagcagttg taaatgaaat ttccaaagaa atatgtgaat
      481 taaaaaacat tgctacatat gaacattttc aaaatatggg ttatgcctca aagatgattt
      541 atcatctttt agatgtttat agtaaaaaat attcatcaat ggttgttggt acatctgaaa
      601 gcggagttcc tttttatgag aaatttggat ttgtttattc acataaaatt aaaaactttt
      661 ttgtagataa ttatccagaa ccaatctttg aaggagaatt acaatgtgtt gacatgttgt
      721 atctatcata taacttttag ataggataat atttttaggt taatataatt aattaattca
      781 tataattatc ggaattataa tttataaatt atgtataata agagtataat ttatttagaa
      841 gctgttatat tgtattagat tcaaataaga tatataataa cttgtttatt ttgaattttg
      901 gaggattaat tatggattca aataataata ctataaaatc aactgttaaa aagggtattt
      961 cttttggttc ttgtttagca atgattattt cttatactgc atggaaatct attccatggg
     1021 ctatttttca tggcttaatg agttggatat atgtacttta ttattgggtt aagtatgcat
     1081 agattaaatt aataaataag tatgtaatat tgtaaagttt aagaaacaaa atgtaaggga
     1141 gtgtctcgaa gtgaactttt agtttataag gcactctttt ttgtattaaa taaaatatat
     1201 tttcattact taaacaatga aaaagatgag tatctctatt ttaatacata cccttatatt
     1261 cattcattta tcaacaatag ttttaaaaag aaagctatct aaaatctatt gtaatctaag
     1321 tgcttctctt taaagtctta actttagtaa tgatatataa gtttataagg ttcttatttc
     1381 aataatgcaa attttactta gaagttcaga ctttggtatg aagaaatggg taataataaa
     1441 aaagaggtgt tgatatgaaa gaaaaattag aagaaaaatc taagattatt aaaacatcaa
     1501 aagagtataa acgaactata attgaagaaa aagacagaga atggaccaaa aaattaaatg
     1561 acatacttag tagaggtgat ttttctaatg aaaaattaga taaaatcaag gatttaattc
     1621 caaaagaaat attgactagt gaaaatgttg gagaagttgt aactgaagat gggtatgcta
     1681 agcctgagta tgatgaggta tttaaatcat tgtttacttt aaataatgat tacgatttac
     1741 ttgcaaattt tataaatgat atcctcaaag atgctccata tgctaatagg aatatcaaac
     1801 agttcactca aataaaaaga ataattaagg ttgaaaccga cccaacaatt aattacattg
     1861 gtgagaaaag acctagactt gatattttgg ctgaagatga agaacgtaac catataaata
     1921 ttgagatgca aagagctctt gaagaggatt atttggaaag agctgaatat tatcttagtc
     1981 gtgtacatgg tagaaagtta gaagaaggta aagaatataa agaaattgga aaaactgttg
     2041 gaatacatat actaaatcat gtaaaatata atcacataga agattatgta aattgcctga
     2101 gattaacaat ggacgggcat ccagatattt tttctagtaa aactgcatta tattttatag
     2161 aacttccaaa aattcgtaaa tccagttgta tagcaaacag agttctaata tggggtaaac
     2221 ttattgataa tccttctcat atagatatta gaatactatc taaaacggat tatgttatta
     2281 aaagagcact tgatagatta aaagaattag gtagtaatga ggactattta ttaaatttaa
     2341 agagaggtgc gtatattatg aataaaagta gaaattttaa agaagaaatt tttcaagaag
     2401 gtattgaaaa aggtatcgaa aaaggtattg caaaagggaa aagagaagag aaatttaata
     2461 tcatcataaa attaaaaaat aaaggataca atttgagtga aatatgcgat attatagatg
     2521 atttgaataa atcagaggtt gaaaaagtct ataatcaaaa ctaatactat gattgagatg
     2581 gcactagata aatacaaagc ttcctctttt aaatttaaat taatataaaa ctttgctatt
     2641 taaatatggt agatataaag agatatataa ataataggta caaagaggtg tataaataaa
     2701 ggagataatt caaaataaaa gtttgaacca tctccttctt atagaaaaac aaaggggttg
     2761 atttatatat gaaattttat actatacaga ctttagaatt ttggaataac aataaaaaca
     2821 ataaatatct atcaaatgat tattctttta tattagaaga ctttgatatt ccatacaaat
     2881 ggatgtatag tcaaatgaca aatagaatat atgaatttga tgatagtatg atatgggttt
     2941 ggacgaagag acctgattta agatgtagtg gttatttaga aaaaggaaaa aaaggtgttt
     3001 tacttgaaat agaaataagt gaagataatg tgttattatc agaatttgat ttatggcatt
     3061 tacctttaat ggatattgct gtagagcttt atgaagatga acaaattgaa aagaaggtaa
     3121 gttgggaaag aatatttgac ttagaactgt gttcaaaatt aaatgaagtt aatatagaag
     3181 atttgacatt gcaaggagtg acatctaaag tgcctctatc taatgtaaaa ttaataaaag
     3241 aatttgttgc aaaataatat ttttattgaa atttattcaa aaaagttata tatttataac
     3301 aagaggtgtt ataaatacat aactttttaa gggggatttt atatgtctaa acaacaaact
     3361 ggtattaaat caacacttat ttcagaaata ttgggaattt cttattgtat tggagctaca
     3421 ttagtaaata agtatttttt taaaggaagt agtattgaat atcttcctat aattatttgg
     3481 gtattagcta tgggagctca gtgggtctat aataaaaagt atgatgattt aattgatgag
     3541 gcatcaaaat gtatactatc aagagttaat gatattgcaa taaaagtatt gtttttttct
     3601 gtagctatag tatctatatt tcttgtaact ttggacataa atgtgtcaaa tttaaatata
     3661 ggaatgtctt tattagtcat tttgtttatt caatccttgt tgaagttaat tctatttata
     3721 tattttgaca gaaaggggat atacaattag gtgtcagtat tactaaagac aaaaattaaa
     3781 tcctatagag aaaagaacct tatgacacaa ggtgaacttg caaagtcagt aggagtaaga
     3841 cgtgaaacta ttgtacattt agaaaatggt cgctacaatc cttctttaaa actggcaatg
     3901 gatattgcta aggtatttga tacaattgta gaagagttgt ttgaatttat tgaagaaaat
     3961 aatatttaaa tttcatgtat tacttatgca ttagagaatg aattaattat aggtaaaaaa
     4021 ccaagcttat agattagaga ataaatgact tatagatgaa aaaccaagct aatggattaa
     4081 agaatgaatg atttatagat gaaaaagaaa gctaatagat tagagaataa atgacttata
     4141 aataaaaacc aagctaatag attagagaat gaattaatta taggtaaaaa ccaagctaat
     4201 agattagaga ataaatgact tataaataaa aaccaagcta atagattaga gaatgaatta
     4261 attataggta aaaatcaagc tcatagatta aaaaataaat gatttataga tgaagaacta
     4321 aacttataga ttaaaaaata aatgacttat ttatagatga aaaaccaaac ttatagatta
     4381 aaaaataaat gatttataga tgaagaacta aacttataga ttaaaaaata aatgacttat
     4441 agatgaaaaa acaagctcat agattaaaga ataaataact tattagatga aaaaacaagc
     4501 ttatagataa gaagtccatg cttataagcc agaaaatgaa tagtttaata gattaaaaaa
     4561 tacatatttg tgaattatag aatgaataac tccataaact agaaaattta taataatatc
     4621 tatatgaaaa ttagaattat tttatcacaa aaaaattaag ttaaataaat atgaaattac
     4681 ttccaaatat acttccaaaa acatgtaatc gcatatataa tataattata aaaataataa
     4741 atatttttat agtagtagtt aattattaat aaggaggggt caaaatgcct agcatgatta
     4801 tggaagttgt aggagtacta tttatagcta ttggattaat cttgacattc attgaaataa
     4861 aaggaaattt cccttctttt tatggttttg gtcaaaatta aaatgctgta ggtattatag
     4921 cagcaggaat tgctttaatt ttctttagaa atggcataga tacatagatt ctatagctac
     4981 ttatggtgta tttttagcaa tagaacttgt tgtaatagtt gcatatttct taataagaaa
     5041 aaaatttact aaagaagata aacatttaag aactaattaa ctaaattatc tactataaaa
     5101 ttggaaaatt aaaaacaaat aaaagtttgt ttttaattat ttaaaatcca aatttgatta
     5161 tttttaaaga aactatgttc tgtataaaac tagaatgtgg tttctttttt atgtataaaa
     5221 tattttttag caaaagttaa aaggtgtttt ataatataaa atagttaatt gtagatgtta
     5281 ataaaagaaa attatgtata ttttagataa agataagaga gtatactata ttttaattct
     5341 tttttcaata aagcttattg aaaagaactt taacttagaa gagtatcacc aaattgcaga
     5401 tacaatatca taagcagtta tttattgaca acccttttta ataaatatat catttgaagt
     5461 atactgacga aaaggagttg aataataatg gacatcttat tggttgaaga tgataagaat
     5521 attcgagaaa tggtatacga ttttctgatt agtgagaatt actctgttaa aactgccatt
     5581 gatggaaata cagctattga aatatttaaa aattattcat ttgatattat tttactggac
     5641 ttgatgttac caaagtctag tggttttgaa gtattaaaat atatacgaag tgtgagtgtt
     5701 gttcctgtta ttattactac tgcgaaagat agtgacacag ataaaatgct agggcttaat
     5761 cttggtgcag atgattatat tacaaagcct ttttcaatcg tagaattgct tgcaagaatt
     5821 aaagctaata ttagacgtgc aacagtgtat agcagttcaa gaaactctca agatatggtt
     5881 attcggtata aggatttgat tataaacata tcaaaatatg tagtttcaaa gaatggaatt
     5941 gacttaaact taacacatac agaatttgaa attgttaaat tactagcgac taatcaagga
     6001 cgtgcttttt caaaggaaca attatacaac gctatttgga aagaacctta ttatggaaat
     6061 gaaaatgtgc taaatactca tattaacagg ttaagaaata aattgtctga tggtatagaa
     6121 aaaaataatt atattaaaac tctttgggga attggctaca aaatggagga agaataatgg
     6181 agttattttt agttgtaatt tcgattgtac tatttgctct ctacttaaaa gaacgaaata
     6241 aatcaaagaa aatggaaagt gattataagt atatcaattc aagacttcgt gacataacaa
     6301 atgatgatga aattaattat attttagtac catctgatat ttcgattgta aaagaaacag
     6361 cagtagatat aaataaactt gttgaaaagt tttatagcag gcaaattaat tataatagaa
     6421 gtgaaaaagc gatattgcaa atatttacaa acatatcaca cgatttacga actcccatca
     6481 cagtattaaa gggttatatt gaaatgctat atcttcaaag tcaaaaagaa gaattatctt
     6541 cttcaatgag agcaactgtg gaaaaaatgc aaacaaattc aaatgagctt gttaattcaa
     6601 taaataacct gtttaatatg gcaaaaatcc aatctggaga tatgatatta aatcttcaaa
     6661 aatccaatct aacacaatta tgtcatgaga ttattttaga gttttatgat ttgctagata
     6721 aagaaaactt taatgttgaa gttaatattg aagatagacc tatatatgca aatgttgaca
     6781 cagaagcatt acaacgtata ctcaaaaatt taattgataa tgctataaaa tatggttcag
     6841 atggtagatt tttagggatt tcactatatg aaaaggaaaa acatgttttt atagatattg
     6901 aggataaagg ttcaggtatt tctgaaactg aaaaagagca tattttcaca agagcttata
     6961 ctgctgacag aaaaaaaggc aatggtttag gtttggctat ttctcaaggg cttgcaaact
     7021 ctatgggagg ttcaatttat gtaaatagta gacctaatgt aaaaacagtt tttacggtaa
     7081 aattgaaaag ttagaaaaaa gttagattta aaagagagaa aagataattt tattttgtat
     7141 actgttttta gaaaggaggg agtatgatga actatatcat agagacccat caattaaaga
     7201 aaatatataa agataaagct gttgttaatg ctgttaatat tcatgtgaaa aagggagaaa
     7261 tttatggatt tgttggacca aatggagcag gtaaaagtac agtaatgaaa atgttgctaa
     7321 atcttgttaa gccaaattct ggagaaatag ttatgttcag taagaaagtg gcagaaactg
     7381 attttgaaat attaaaaaag attggtacta ttattgaaaa tccgtattta tatgagaatt
     7441 tgactgctaa acagaatctt gatttacact gtgaatatat gggttattat aacaaagaac
     7501 atatatcaga ggtattggaa tgtgtcggat tgtcaaagca atcaaacaag aaagtttcaa
     7561 aatattcttt agggatgaaa caacgtcttg caatagctag agcaattctt actaaaccag
     7621 aattattgat tcttgatgaa cctataaatg cactcgaccc agaggggata agagaaatgc
     7681 gagaattatt ccgtaagtta aatacagatt atggaataac tatatttatt tctagtcata
     7741 ttctttcaga ggtagaacaa attgcggaca ctattggaat tattcaagat ggtaaactta
     7801 ttaaagaaat ttctatgtca gatatacaca aatatcaaac agattatgtt gaagtagatg
     7861 tagataatgt ggaatttgct ggatacttgt tagaaaaaga atttggaata aaagacttta
     7921 aaattacttc ggaaagttgt attgaaatat atgatttacg aaaagatgta aaagaaatat
     7981 ccaaaatatt tattcaaaat caaattggta taaatagcat tggtcgtaaa caaagttctt
     8041 tagaagatta cttcttccaa actacaggta caggaggtaa agaaacacta tgatacattt
     8101 aatgaaacta gagctaaaaa aagttgggct aaaaagatat tttttatttt caatgctggg
     8161 gattttctta tgtatgtttt ttgtctttac tggattgaat gataaatcta cttcaatata
     8221 tgattatgat gttacattta ggacaatcag tttatttttc tgtttttact atattatatt
     8281 atttgctgtg ttgaatgtgg catatataat aaatgaatat acaaataaaa caatcttgat
     8341 tttattctct tatccacttg accgtaaaaa acttatttta tcaaagttac ttttgattac
     8401 gactcttatg atatcatcaa tgataattgg atatatctgt tgttttacat tcgttgttgt
     8461 gttggataag tattttaatt tagttattgg agattttcat atttctattt tatcttattg
     8521 gataccagga gcaattaaaa gtattattgt attttgctca ttaggtatat ggacattcgt
     8581 tgttggaatg ataagaaaat caatacctgt tacccttgtc agttcaatta tttttatcaa
     8641 tttaagacaa tttattttag ctggtacaaa tacaactcaa gacagtttga tttctgtttt
     8701 tattatagtt ggtataactg tgattggtat atattatata ctaaatcata aagttactga
     8761 aattgactag atactgtgga taggaaggta gttattaatt gtatcttctt gggagaataa
     8821 tgatttgcta ttatatcagc tattattaat attattagag ttttaataat attgcacaac
     8881 catttgaagt tgagccaaag cttgatgaat taattgaatg gtactatagt cagagtgaag
     8941 tatctattaa agttatagct gaatttcatt atagatttga attgatacat ccatttcaag
     9001 atggtaatgg tcacataggt agatttgtta tgctaaaaca gatgttagaa aataatcttc
     9061 ctataaaaat tgtatcttgg gatagtgagg acttgtatag aaactcctta aattcttgta
     9121 gtttaggtaa ttatgtccct ttaattgaat atttatcaag tttagaagat tttagagaag
     9181 tatataaaat gttatggaaa taattgtttg tagcaaaaaa agtttatata taaatatatt
     9241 tttaactatg gtatttaacg ctaatttctt agttattctt agcttggact atactcacta
     9301 ttttaactat ataaaatagt ggatatagtt taactatctc tttataacta ttcttatgta
     9361 tcttagttgt ttcttaatat ggggacagtt cataaaacta aaagtgattt ttaattttat
     9421 catttataat ttaccattac atcagaaaaa tgcttatcat tagaattttc ataaaaggta
     9481 cctatttttt tcaattaact aaatcaattc tattagtctt aatctttcgt atttcaaatt
     9541 gataatataa gaaaataaaa aataaaaaat tttaaatttt ttatttattg cgaaaaaaat
     9601 aaaaaggtgc tatacttttt gtaacatatt attcaaatta ttaagagata gtaaacattt
     9661 atagtttaat ttgtagtaca ctagcatgat ttgcagaaca atgaattaat ctatagtata
     9721 atagtttaat ttaaagtaca acgatttaat ctatagtaca ctagcatgat ttgaagtaca
     9781 acgatttaat ctatagtaca ctagcatgat ttgaagtaca acgatttaat ctatagtata
     9841 atagtttaat ttgaagtaca acgatttaat ctatagtaca ataacttgat ttgaagtata
     9901 acgatttaat ctatagtaca ataacttgat ttgcaataca atgaattaat ctatggtata
     9961 atagtttaat ttgaagtaca atgaattaat ctatagtata atagtttaat ttgaagtaca
    10021 acgatttaat ctatagtata atagtttaat ttgaagtaca atggtttaat ctatagtata
    10081 atagtttaat ttgaagtaca acgatttaat ctatagtaca ataacttgat ttgcaataca
    10141 atgaattaat ctatagtata agagcatgat ttacagtaca ataatttaaa ttgtagtaca
    10201 aaagtactat caaataagaa tttctacttt aaaaatatta ctaaaagtaa ttaaagtcca
    10261 gtaattcaat ataatatggc aaaagaatag aaataaggtg agagtagtga aagtaaagtc
    10321 aaatttagat gaaattttat atcataagat tattgaaagt cttattcgtg gtgaatactc
    10381 tgtaggtcaa aaaatattac taaatgacct ttgtgaaaaa tttgaagtaa gcagaacacc
    10441 agttgtacaa gcagtaaaaa tgctaaataa agatggagtg cttactatta tgacaaatgg
    10501 taaagtgtac gtaccagagt atgaatatga tatggtaaaa caagtttgtg aaacgagaac
    10561 actgattgaa acatatgctt tagaaaaaat gatgcaagaa gaggaagagg tttttcaaca
    10621 aaagctagat gtaataaaaa gatactctga taaatgcgag gagtactatc gtcaagaaaa
    10681 atctgtagaa cttgcactag cagatttgga attacataaa gccattgtag aaggggcaaa
    10741 taatgagatt ttaaatgatg tatatgttgg tatacaagga agatttatag tagtgaacta
    10801 tttaattcga ccattaaaaa atcgtaatta tgaaggaaca gtacaagacc attttgaaat
    10861 attaaaattc attgaagaca gagatacaaa aaaagcagta gataaactaa gaaatcatat
    10921 tcaaggaact attaaaagat tctgtgaaga tgaataataa gttttgaagt tactatatat
    10981 acttatctat taagttgcta aatgtagtct aagtataatc taattatagt ttaaacataa
    11041 tctaaatata atctaataaa tataatctaa atatagtgta aataagtcta agtatgaatt
    11101 aaatatagat taagtataga ttaagtatga attaagcatg aattaagcat ggattaaata
    11161 tactttaaat tacaaatatt acaaggaagc cagaaggctt cctaaaaaaa taacctttat
    11221 aaaatttttt attttaaatt taaaataaaa aatgaaagag gtggtagaga gtttgaaaaa
    11281 aattactaaa gaaaggatag aaaatactat gaaaaagcta tttacgagtg aaacattttt
    11341 ggaatatcaa tttataagtg attgccaaat atcaccaaat ggaggatata cagcatttat
    11401 tgtaaaaaaa gctgatatca aagagaatgg ttacacaagc caagtttata tattaaacaa
    11461 taaaactggc gaattaaaac aaataacgtc tataaactct gttggagcat atgcctggga
    11521 agatgaaaat actatcttgt tccctgcttt gcgaaatgaa aaagtaaaag atgctgtcaa
    11581 aaacggtaag caatgcatga gttactatgc tttatcttta aatggtggag aagcagaaga
    11641 actttttaga ctccctatca aaggtggtaa attgaatcct ataggaaaag gtttgtatgc
    11701 agttattgat tcttatgaca atgaccgacc tattgtagag ggattgccag aagaagaaca
    11761 acagaaaaaa ataaatgctt ataacaaaag acattatgaa catttcaaag aaattcctta
    11821 tgctgtcaat ggggagggat atattagcag aaaaagaaaa cgcctatatg tatacgatag
    11881 taatataaat gagttgaagg caattacagc acctatgttt aatgttgtag gtatgaaaat
    11941 aagtgatgga aaaatcttat atatagggca agagtttaaa gatgtaaaag gtttgaaaaa
    12001 tggggtctat gtatttgata caaacacaaa cacaaatgtc tgtatattag aaaaagataa
    12061 gtatattata aaaggttttg aattatatca aaatcaagtg atactaaacc taactgatgc
    12121 tttatcttat ggaaatggag aaaatggaga tttttatact attgatattg atacgaaaga
    12181 aatgaaactt ctttcagggc atcaacatca ttgtattgga aatacagtaa catctgatgt
    12241 taaaatgggt gctggtcaga caacaaaggt agatggagaa tatatttatt acacttctac
    12301 agtagatatg gactgcatta ttgaaagaat acatattcca acaggaaaac aggaaaaagt
    12361 aacacagaca ggttcagttg attttataga tgtaaaagat ggcaatattg tatgtgtggg
    12421 ttgtttagga aatggattac cagaagttta tacagtagag aatggaacat tgtgtaagaa
    12481 aacacattta aatgaccata ttttagagga atataaaatt tctgtgccag aatacataga
    12541 gtcaaaagga agttctaaat gggaaataca aggatacgta tataaaccag tagattatga
    12601 ggtggggaaa aaatatccag ctgtattggt gattcatgga ggaccaagat tgacatatgg
    12661 accatatttt atgcatgaga tacaggtatt tacaagtgca ggttactttg tattcttctg
    12721 taacccaagg gggtctgaag gtcgtggcaa tgcttttgca gatattagga aacagtttgg
    12781 agatattgat tatatagatt ttatggaatt tacagatact gtacttgaaa aatatacaga
    12841 cattgataaa acaaaattgg ctgttgaagg tggaagttat ggtggattta tgacgaattg
    12901 gataattggt catacaaacc gttttgctgt tgcttgtgct caacgttcta ttgcaaactg
    12961 gagtggcatg gagggtacaa cagacattgg ttattatttc tgcaaaggac aaacaggtgc
    13021 ttctcatatg gaaaaccacg agcttcaatg gaaacagtca cctcttgctt atgctgataa
    13081 atgtgttaca ccgactttat ttttacatgg tgaaaaagac tatagatgct atatgcaaga
    13141 agcattccag atgttttcag cattgaaaat tcatgggtgt cctacaaaac tttgtctatt
    13201 tgaaggagaa aaccatgaac tgtctcgttc tggtagacca aaacaaaggc tacaaagatt
    13261 agttgaaatg ctagattggt tttcggtata tataaaaaaa gataacatag gacagtagaa
    13321 aggagaatat aaaaatggaa aaaataaaga ttgaaagttc agatattttt gaatatatat
    13381 tccctcatga tatttcttgt tcacctgatg gaaagcatat tgcttatatt atatcaaata
    13441 tcaacgagga aaaagactgc tatgaacatg acttatatgt gatggacatc aaaacagaaa
    13501 aacaaataca tatgactcaa acaaaagatg taacatcatt tagttggatt tctaatacag
    13561 aactactttt tacatctaaa agaaataagc caaaatcagg tacaacagat ttttacacta
    13621 tttctataga aggaggagaa gcaaaaaaag cattttctat tccaaaagct tgtagcgtac
    13681 ctgtatcact tggaaataaa ttgtggttac tgacaacaaa aaatccaacg gattctaaaa
    13741 aatcagaacc agatagggca gtagagggtg tagattattg gacatttaca gataaacctt
    13801 ttataagaga tggagaaaat ttttctcaaa gaagacgtgt aacattagaa ttatatcaag
    13861 aaggtgaaaa tataacaaaa gccattacac caaaattttg tgaagtagca ggtatagaca
    13921 tttcttctga taaaaacaga attttatata ctggtcagat ttatgaagat tgtgcaactc
    13981 ctttttctgg actttgggag tatcatatag acagtggtga aaccaaagaa cttgtaccac
    14041 aaggaaagta ccaaataagt ttggcaaaat atattggcaa agataaagta atgttgcaag
    14101 cttcaacatt agaccgttct attacacaga atcatgatat ttttatactt gatttgagta
    14161 ctagtgaaat aaatatgatt gctagtccag atggtatgta tgctacatta ctggatgtag
    14221 atgcagtata tggtggtgga cgtagtaata aagttatagg agacaaattt attggtgcaa
    14281 gaatttgcag aactatgaca gaatttaatg agtttgatac aaagacaggt aatatacgta
    14341 tcatcacaaa agtagatgct tttacatctt ttgatattta cgacaacacc atgtacacag
    14401 taatgttgaa agattatgag ttagcagaaa tatatagcat tgatatgact acaggtacaa
    14461 tgaaaaaaat gactgctttt tctaaaccat atttagatac tcataaggtt tcattacctg
    14521 aaaaattgac gtttgtagca aaaaataaag aagaagttga tggttttgtt ataccgccta
    14581 tagatgctaa agaaggcgaa aaatatcctg ctgtattgtt cattcatggt gggcctaaat
    14641 gggcatatgg ctatatgttt acacacttga agcagtgtgt aacatcaaag ggaatgtatg
    14701 tgatttattg taaccctcat ggtggtgacg gttatggtga aaagttctta gaaatggtag
    14761 aaagatgggg gtatgttgac tatgagcatc ttatggaatt tgtagatact tgtattgaaa
    14821 aatatcctgg gattgatgca gaccgcttag gggttgcagg gggaagttac ggtggttata
    14881 tgacaaactg gataattggt catacagacc gtttcaaagc agcagcttct caaagaggta
    14941 ttagtaactt gattacagct tctttaatta ttgactttgg agatagaatt atgaagcaga
    15001 cttgtggaga taagacgcct tggaatcatg aggaggttct ttggaatcat tcacctatta
    15061 aatatgtgaa aaatgttaag acaccaacat tgttcttaca tagcgatagg gattatagat
    15121 gttttatggg ggatactttc caaatgttta cagcattaaa acagcttggt gtagatacag
    15181 aaatgtattt gtttcatgga gatacacatg gattgtctag aaatggaaga ccatctaata
    15241 gaattgcaag agcaaatgct attgtagatt ggtttgaaag atatttataa taagggggtt
    15301 attctatgag tgatatgtta ttatggttta gtgtcgtatt agttttattt gctattgggg
    15361 atttaattgc aagcaaaaca aaagcaaaag tatcagctgt atttgttaca ctacttttat
    15421 ttttgattct atttgtcaca aaagcaatac cagctgatat tattgaaaaa gcaggtatga
    15481 ccgcagcagc tagttggagt gttccaatga ttatgtttag tatgggaaca atgttgaatg
    15541 ttaaacaatt tatagacgaa tggagaacag tattgacagc atggcttgga attgtagcag
    15601 ttatagtctg tgtctcatta tgtattcctt tgtttggaaa atcaacagta ttgacaagca
    15661 taccagttat aaatggagct ttacctgcta ctactattat gacacaagca gcactagaaa
    15721 aaggactgac acttgcagca gctacagcaa cagttgtatt tgcaattcag aagtttattg
    15781 gtacaccaat agcttcaaga gcagcgttac aagaggcaaa ccgtctttta gtagaatatc
    15841 atgaagcaaa atcaaaaggc attgatttag caaatgttga tactgataag aaagaagcag
    15901 agaatacagg cacaaaagta aaacaagctt tctgtgaaaa atacgataaa tattattcta
    15961 caaatgtttg tatatttttt atagcactat tctcttatct agggtatgaa ctttcagaga
    16021 ttattcatgt aaattattct attgtatgtc ttgttgttgg tgttattgta acacgtattg
    16081 gtattgtgcc aaaagacatt ttggaaaaag gaaaaatcaa gggatttatc aacatggttg
    16141 tgtttgcagc tgttattcct tctttagcaa aagtttcttt gacagattta attagtcttt
    16201 ttgtaccaat tgtgggtatg tttgcagctt ctatcattgg tatattcctt atgatgaagg
    16261 tgttaccagg ttggaaaatt atcggttcta aacctcttgc ttttggagta gggttttgtc
    16321 agatgttggg attcccaact acatatttaa tttcaaatga agtgtgtaat gctgttggag
    16381 aaacggaaga agaaagagca tatttgatgt ctaagattat gcctaagctg gtagttggtg
    16441 gtatggcttg tatgatttct attgtggtag ctggtcttat ggtaccaatg ttgtagatag
    16501 gtttcaaagt taaaaaagtg gtattaattt ataggagaag ctaaaaagta gtattaattt
    16561 ataaaataat tttatattag ttaatttgtt ataagaatat tttcttttta taattataat
    16621 tttgatttta taagagagca gattttttat ttgctatgct aatagttata atttgttttt
    16681 atttgctaaa atgcaacttt aatttgattt atgtataata tagggtattt aataatattt
    16741 ttgaagaatt tttataaaaa attaaaaaga ggagaaaaaa gggagtggca caaagtgaac
    16801 tttttagttc ataaggcact cttttttgta cgaaatcgaa tatattttca acgttttaaa
    16861 agtgagaaag agacttatct ctagtttgag atagccaatt ttaattatta aaattatttt
    16921 ttgttttatt tatcaaagag tatccgtgtt ttagaagtta gtatttttta ttttatatat
    16981 ccaaggtttt ccgtttctaa tgttttcttt tttaaaataa ttagggtatt caattatggt
    17041 aaaaggtgga tggtattttg cagtgatatt atttaaagca cagtattgaa tgttgaaatc
    17101 ctcacatttt agagtattat cttttataat caaaaaaatc ttctatactt atagcaaggt
    17161 tatttctgca aatattccat gcatcataat atctaaattt aaattttttt aatatagagt
    17221 ttacctctag tctacactct tgaataactc tttcctctat ccaaattctt ataaattcat
    17281 cccatttatt actatttatt tattactatc taaatttttt agtatgtttg taattagaaa
    17341 tggatttatt cctttatgtt ttttataaat agtttataac ttaatttatc atcaaacaaa
    17401 tcattcatac aggattactt tttcttttag atattcaatt cttactttta ataaatattt
    17461 aatacattct atcttatgtg gttttaaaaa gtgtttatgg ctatcaacaa tctctaatat
    17521 ttcattcata tttattttgt catagtaata ttttacatct tttatattga caaaaaagtg
    17581 ctctaagtgt atagtgtgta tatgataaca tcacactgaa agtgataaaa agggggtgat
    17641 aaaaaatgaa agtgctcatt tctaacacat cagataagcc attataccaa caaattaaag
    17701 agcaaattaa agaagcaata tttactgaag aactgaaaga aggggatgca atgccatcca
    17761 taagaaattt tgctaatgat ttaaaagtta gtattttgac tattagacga gtgtatgaag
    17821 aacttgaaaa tgaaggcttt cttacacgcc aagttggaat aggaacattt atttcaactg
    17881 gaaatttaga aatactaaga gactcaaaga gacgtatagt tgaacaaaaa atggcagata
    17941 tgattaaaga tgcaaaagca ctaggaatta cacagataga gttacaagaa atgatggata
    18001 ttctatatga ggaggattaa tatggaaaat attttagaag tttataactt aaataagact
    18061 tataccgatt tttcattatc taatataagc tttgcattac cagaagattg tataaccgga
    18121 tttataggtg ttaatggagc aggaaaaaca acaacaatcc gttcgatatt ggatgtcgta
    18181 aagcgtgata gtggaaaaat aaaaatcttt ggtaaagatt tcgatggaaa tgagaaggaa
    18241 ttaaaaaatc gaattggagt tgtctttgat gattcatatt tctatgagga gttgtcaatg
    18301 gcagaaatga aaagtattat tgcaccttca tatgataatt ggtgtgaaga agattatcaa
    18361 caaaatatga agcgttttaa tcttaaccca aaacaaaaga ttgatacact ttcaaaagga
    18421 atgaaaatga aatttgcttt agcattagca ttatcgcata aagctgagtt tttaattatg
    18481 gatgagccta caagtggttt agacccacta atccgtagtc agatacttga catactaaca
    18541 ggatatatga agaaatgtgg tcgtggtgtt ttcttttcca ctcatataac atctgattta
    18601 gacaaaatag cagatatgat tgttatgatt gacaatggac gtattatatt agagcgtgaa
    18661 aaagatactc tattggacga acatagaaaa gtaaaagggg atattcaatt tctaaatgat
    18721 gaaaccaaaa aattattttt aaatttagaa attacaggtt atggttttat agggattacc
    18781 tcaaaaatta atgaagtgca aaaaaatatg ccagatattt taatagagcg tcctacaatt
    18841 gaagatatta tgcttgcata tattgaaagg agagagtaat tatgttgatt catttagtta
    18901 aaaaagatat tctgattgta aaaaaatatg tattgttgat attatttatt gcaataggaa
    18961 tcccattatt tatattatgg cgtttacctc catttgcaca aatattggga tttgtactat
    19021 caattatatt ttcagaattt atgctgtgtc agtatctatt attaaaggag agtcaatatt
    19081 caaaagcatc tgtattactt tgttcaactc cttatcctag acgtggctta gttcaatcta
    19141 agtatgtttt atttgcaatg gtatttatct attgtacatt agtttactgg attgaaaatt
    19201 tacttattcc acaaatagga acttttgact tgacatatat tttgattgtt ttattaataa
    19261 gttctattat ttatggagtt tatatgccta ttcaatacaa attaggatat gaaacaacaa
    19321 aattcttttt cgtgatgata atcatggctt catcatttgt attaccatta actatagctc
    19381 acagcaattt tgaaattcca tttatatatc agtatccatc catgatagtg aatattgtat
    19441 tgttcctttt aagtttaatt atactgttag cttcaatgtt tatttctatt aaaattttta
    19501 gtaataagga gcttgtataa ggtaaggggg acttttatat gccacattta ccagattggg
    19561 ctgttttact ttgtatctta cttccaatag tatataaagc ttgtcagata tttaaaagta
    19621 aaaaatagag tacatattta tattgccatt tttattgagt gaagttagat ggtatgaatt
    19681 taaaaggtta cttgaaaata aagttacttg gtgcgggaga gtaacatcat aatattatag
    19741 attatatgtt tcttgtgaat caatttgtat tttttaatag ggaatatcca gtaattttat
    19801 tttccattga ttatttttca attatgagta tgattgtgtg tattgtatac caccttttaa
    19861 gatgttttta aaaaattata tcgtcaaaat ataaatctaa ggaatcctat aaataaagct
    19921 tttcaatttt agaaaactaa taaaaagtag gaaattaata aaaagaagct gtctcaaaat
    19981 agagataagt ttctttttca ttgctgaaat gacgaaaata taattgattt aatataaaaa
    20041 agagtgcttt atgaactatt tattttgaac agtagataca cttgcactca atttagttcc
    20101 tcctaagctt tatgaactaa aagtttattt tgaagcttat ttttattaaa agagatttta
    20161 tttttctaaa taatcatcta tatacagtat tgcgtttctt ttatttattc ataatttatt
    20221 ttcttattaa agtttttcta tattcatatt ttccatatta ctttactttt aattttatac
    20281 gaatatacga attatcaaaa ataaaatagt tattagaaaa aaataaaagt aattgcaaag
    20341 cttgcaatta cttacttcta tattaattac tataccataa aataacaaaa aaatcaagtc
    20401 gagtaatcct tcaacttaag tgatatacta ggtattaata atttttaatt aataaaatat
    20461 aactagagga aaatctacat tttctcaatt tctttaatta aattgacctc taattaagta
    20521 attataagga gaaaaattat gaatttagca aagggattag atgttttaaa aatttcatca
    20581 aatgtattcg gtgaagataa agttatgtat attcctgtaa tctacacaga agatgatgca
    20641 acacttattg acacaggtct tccgggtcaa ggtgatttaa taattgatgc tcttaataaa
    20701 agtaacacga gctttgatag gttaaaaaat ataataatta ctcatcatga tatagaccat
    20761 ataggaaaca taaattatct aagagaaaaa tctaagaata atatcaaagt atatgcatac
    20821 aaaagtgaaa tcagctatat aacaggagaa gaaactcctt ttaaacttta tatgttggaa
    20881 caaatggtag ataaaattga tgataagatg cttagtatgc taaatgttat gggacttgga
    20941 tttaaatcat catatactaa agtagatgtg tcattagata accatgaaaa attgaatcta
    21001 ggtgaggaaa tagaagttat acatacagga ggtcacacta gaggtcacat atgtctttat
    21061 ttaaaagagt ctaaagtact tattgctgga gatttgttac aggtagaaaa tggagaactt
    21121 aagcctgttg atgtaatgca cagcaacaaa caagagttaa aagatgctat taaaaatata
    21181 agtaattatg atatagaaac gatagttttt agtcatggtg gattatatca aagaaacata
    21241 attggaacat tgaaaaacct aattattgag tagtactata tgatttacaa taatttctta
    21301 aattacttaa aattatatct aaagatgtag aatcaaaatt aaatataagt aataagaatt
    21361 ttgctttaaa attatactta agtgttaagg gtgatacgta gtattacaag tattttagaa
    21421 tataattttt tatagtaatt ttaaagttct acaatacttc agttgaaaaa tatttaacag
    21481 catagtataa taggaaagaa aatactttaa ataaacttta gtatacaaag tgaagaaaaa
    21541 tatttaaatt atatataata ttgtagagtg aggtaaaata tttaagttat atatcataat
    21601 acagagtgaa gaaaaatatt tagataatgt accataatac aaggtgagta aaaatattta
    21661 aataatgtat cataatgcaa agcgaagaaa aatatttaaa taatgtacca taatgcagag
    21721 tgagtaaaaa tatttaaata atgttttata ataatacaaa gtgaataaga ttatttaaag
    21781 catgtattat aatataaagt gagtaaaaat atttaaatca tgtatcataa tacaaagtaa
    21841 agaagattat ttaaaccata tatcataatg caaagtgaag aaaaatgttt aaattatgta
    21901 tcataatata agcagagtga agaaaaatat ttaaataata tatcataatg tagagtgagt
    21961 aaaaatattt aaatcatgta tcataatgca aagtgaagaa aaatatttaa attatgtatc
    22021 ataatataag cagagtgaag aaaaatattt aaataatata tcataatgta gagtgagtaa
    22081 aaatatttaa atcatgtatc ataatataag cagagtgaag aaaatattta aatcatgtat
    22141 cataatataa gcagagtgaa gaaaaatatt taaataatat atcataatgt ggagtgagga
    22201 aaaatattta agttatgtat cataatacaa agtaaagaaa atcatttaaa ttatatatca
    22261 taaaaataat atgaaatatt gaacactcat aatattagag actttaatat tttaattgat
    22321 aggttatatt atttataaca ttaaaaatac aatttacata aaatagacat atgaaaaata
    22381 aaaaattata taataattat gggaatgagg ttctcccttg gatgataata tcctaaactg
    22441 ccaatgagct gatgacttct atgatatcat agatgccacc agcttttttt gttgtttaaa
    22501 tcgataaaat ggaggtgaat tacttactaa atttttattt tttaaatttg aagaaatatt
    22561 taatcaatag aaaaaatagt agattatatg ttaattattt tattaagaat gggttaagag
    22621 tgtacctata tcctatcaat ttaaaaaaca attacgatag tcattacatt gactacagtt
    22681 gatgcaataa aactttcaaa aaatcttatg atgcaaatag aaaggaatta aaatgataga
    22741 aaaatttaaa actttaatat ggattaaaat gataataaga attaaaagcg tttataaaac
    22801 atatggtgga ctattttttt taggactcat aggtatacca gttggtgcaa ttataggtct
    22861 tatagacacc atatttggaa cggttcttct aaaagttaca gatatccgag aaacatatcc
    22921 aatgtatctg ataccatttt tagcagtagt aggagttgtt attgcttatt gctattttaa
    22981 atttggagga aaaagtagta aaggaatgaa tctaatattt gaggtagggc atggagaaga
    23041 agaaattatt cctttaagat tggttccatt tataatatca ggtacatggt taacccattt
    23101 atttggtggt agtgcaggac gagaaggagt tgctgttcag attggtgcaa ctttttcaca
    23161 ttgggtaggt aaaaggttgc ctataaaaaa tgcttctagt atttttctag taactggtat
    23221 ggcagctggt tttgcaggat tatttgagac accaatagca gcaatactat ttgctatgga
    23281 ggttttggta gctggttcac tggagtatca atcgcttttt cctgcgttta ctgcttcttt
    23341 tacagcaagt tcagtatcaa aagctttagg attagagaaa ttttcttttg cactttcttc
    23401 taaagttgta tttgacttgt caatattttg gaagcttatt gttttaggaa ttatttttgg
    23461 aatggttggt ggagcatttg catggtgtct gaaattgtca aaaagaaaaa taggtaatag
    23521 attaaaaaat cctatgataa ggattgctat tattggagta tgtcttagtg tattattcct
    23581 tttattttat aaaggaagat attcaggttt agggacaaat ttaattcaaa atagtttcta
    23641 tggtggagaa atttattcat ttgactggct gttaaagttt atacttacaa tactgacttt
    23701 gtcagcaggt tttcaaggag gagaagttac acctttgttt tccattggag ctagtcttgg
    23761 tgtattgtta gcaggatttt ttaatttgcc aattgaatta gttgcagcgc ttggctatgc
    23821 tagtgtcttt ggtagtgcta caaatacttt ttttgcacct gtatttatag gggcagaagt
    23881 ttttgggtac agctatttac cttatttctt tgtagtatgc gctatttcat atatatttaa
    23941 tatggataaa tctatttatt cactacaaaa aatttcaaca aaacaataaa taaaacaaca
    24001 taatgtatga ttagaagaga aagaatatta gagaaaggat agggtaggaa tatgttgaca
    24061 agtttagctt tgattttttt attaggaatg gcctcgggag gtatttttaa gaggataaaa
    24121 ttacctaact tattgggaat gttacttaca ggaattatat taggtccata tgttttaaat
    24181 ttgattgata attcaatact agatatttct tctgacctta gaaagattgc attgattatt
    24241 atattaacaa gggctggatt atctttagat ataaacgatt tgaagaaagt gggaagacct
    24301 gctgtactta tgtgctttat tccagctact tttgaaatta tcggaatgat agttttagca
    24361 ccaaaattac taggcgtttc tatattggaa gcagcagtca tgggtgcagt agtaggagca
    24421 gtttctcccg caattattgt acctaaaatg cttaaattaa tggaagaagg ttatggtaca
    24481 gaaaaaagta ttccacagat gcttttagca ggaacttcta tagacgatat tttcgtaatt
    24541 gtgatgttta cagtattcac aggattggca caaggaaata gtatatcagc tattagtttt
    24601 ttacaaattc cagtatcaat tatattaggt gtaatagctg gagcagtgat tggaatctgt
    24661 ttagcagtat tttttaagaa ggttcatatg agagattctg ctaaaggggt gttgctttta
    24721 agtatctcat ttttaatgat aagtttagaa actgctttag agggtattgt gccattttct
    24781 ggattattag cagttatgag tattgggatt ttccttcaga taaaatatcg tgtagttgca
    24841 agaagattgt ctataaagta ttcgaaacta tgggttggtg ctgaaattct cttgtttgtt
    24901 ttggtagggg caacagtaga tataagttat gcatttaaag caggaattgg agctgtaatt
    24961 ttaatatttg gagttctttt attccgtatg gtaggagtat tcttctgcct tattaagaca
    25021 aatttgacaa taaaggaaag gttgttctgt atgattggct atattccaaa ggctacagta
    25081 caggcagcaa taggaggtgt accacttgca atggggatgg catctggaca acttattttg
    25141 acgttagcag ttctcgctat acttataact gcacctcttg gagcttttgg aattgatgta
    25201 acttataaaa aattattaac ttctgtaaaa ggcgagagta agtaaaaata aagattattt
    25261 taactggtaa gttatatttt ggaaaaggat tatactattg aatacaatat aaaaaaatca
    25321 tttgggagat taagaaggta gaagttaaga acagatttta aggtatgtta tgattattag
    25381 aattgatttt gtgaaattat tattgtaata tttaattata tagataaaga agcggagtga
    25441 taactatgtg tttaaaaaaa ttatcaaaat tagagttagt tattatgaaa tttatttgga
    25501 atttagatat aaagaccaat tcatatgaga ttattgatta tatgaaagaa gaacataatt
    25561 taccagaaaa agtagcttta aaaactttat caaaactatc aaagaaaaga ttcttatatg
    25621 ttcaagaaac aggcaagtgt atgtattata cagttgcaat aaaagaaaag gcatatttag
    25681 agtttatatc aagaaatgtg caaaatcttt tgaagaataa ttttataagg aatttattag
    25741 tatcatttca cgaagaggag ctaacagagg aaaagataaa gtcgttagaa aactgggtag
    25801 taaattggga agaagcttat gtataaatgt tattattttt attacaattt agataatttt
    25861 ggttttgtaa gctctgcaac tatttttaga tggttgcaga gtttattttt attttttatt
    25921 cccttaagca atacttaaaa gtaaacgcat ttatatttac taacttcaat tacttctaat
    25981 acttaaatta ctttttaaaa atattttgat atgtcatctc tatagtaatc tagaacttgt
    26041 ttctattctt tatataaagt ttttatgaat gatatatata atattcgttc atttgattaa
    26101 aaataacaaa atattaaata attctactct gatagtttgt taaaaaaata ataaaaaata
    26161 ttaataaaca aaaaaaaatt atcttaagag aggagaatgt tctaaaatat aaaaaggttt
    26221 ctagatttca taaaagatac tattttagtc ttgaaaatat ttagtttgaa aagattttaa
    26281 tttaatgatt gattaagtta aaaatgtgta tgtaataaat tttattttat ttattgacta
    26341 aattataaag tttacataat tatttaataa ttatgtaatt gt
//
LOCUS       DAEPUT010000056        25531 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.058, whole genome shotgun sequence.
ACCESSION   DAEPUT010000056 DAEPUT010000000
VERSION     DAEPUT010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25531
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.058"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            33..905
                     /locus_tag="KRL22_002498"
     CDS             33..905
                     /locus_tag="KRL22_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1272973.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            902..2191
                     /locus_tag="KRL22_002499"
     CDS             902..2191
                     /locus_tag="KRL22_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272974.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVISNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKIISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            2121..2765
                     /locus_tag="KRL22_002500"
     CDS             2121..2765
                     /locus_tag="KRL22_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1272975.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(3032..3496)
                     /locus_tag="KRL22_002501"
     CDS             complement(3032..3496)
                     /locus_tag="KRL22_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1272976.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDKRKNFISFINDNKELIGFINLLDEGSSVFFGIGMKPNYCGMGIGKEIISLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYESQGFKIVETKVQKTHLRDGEFFVMRYQ"
     gene            complement(4499..5326)
                     /locus_tag="KRL22_002502"
     CDS             complement(4499..5326)
                     /locus_tag="KRL22_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH1272977.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGSGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            5960..6415
                     /gene="smpB"
                     /locus_tag="KRL22_002503"
     CDS             5960..6415
                     /gene="smpB"
                     /locus_tag="KRL22_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBH1272978.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            6573..6922
                     /gene="ssrA"
                     /locus_tag="KRL22_002504"
     tmRNA           6573..6922
                     /gene="ssrA"
                     /locus_tag="KRL22_002504"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            7254..7469
                     /locus_tag="KRL22_002505"
     CDS             7254..7469
                     /locus_tag="KRL22_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HBH1272979.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKGYIVEDLMQVLKEKGVI"
     gene            7469..7948
                     /locus_tag="KRL22_002506"
     CDS             7469..7948
                     /locus_tag="KRL22_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HBH1272980.1"
                     /translation="MIVYHGSYCVVKTPSITFSRDSLDFGKGFYVTSIKTQAINWTER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFDSYNLEWLDFIIECRNMSDIYMKYDIIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRYEEEV"
     gene            7954..8184
                     /locus_tag="KRL22_002507"
     CDS             7954..8184
                     /locus_tag="KRL22_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272981.1"
                     /translation="MEANKTLLQILYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(8300..9466)
                     /locus_tag="KRL22_002508"
     CDS             complement(8300..9466)
                     /locus_tag="KRL22_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1272982.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPLRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKYLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQGPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNTDILKAGELYINNNYVFCNELGIPIDDKRPLRNLKSILNSLNIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(9456..10208)
                     /locus_tag="KRL22_002509"
     CDS             complement(9456..10208)
                     /locus_tag="KRL22_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH1272983.1"
                     /translation="MNKSYIPKYTHKFPNNIPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILINNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNGN"
     gene            complement(10300..10791)
                     /locus_tag="KRL22_002510"
     CDS             complement(10300..10791)
                     /locus_tag="KRL22_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1272984.1"
                     /translation="MMNNTIGEKIKQYRKSINMSRDELANKIGCSVHAIAKYEQNQRM
                     PSLDMIRKIATALSIAINKLIVEENDLDTLTNNNINLKVFDKELDLVIHILENYGYDI
                     KTDYKKKFEITDNADTIKPINLNFSDFKDFSKNLNWVINGLVENFIQENSNGLIEDED
                     EEY"
     gene            complement(10788..10986)
                     /locus_tag="KRL22_002511"
                     /pseudo
     CDS             complement(10788..10986)
                     /locus_tag="KRL22_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729178.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11043..11804)
                     /locus_tag="KRL22_002512"
     CDS             complement(11043..11804)
                     /locus_tag="KRL22_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272985.1"
                     /translation="MQIGKNLKKIRKQKELTQIQLAEISGISRNALINYENDKRIPSI
                     DTLSKLAKALKIEKTIFYFDIENEVMTNEDVLYLLQSLFPEEYYSFDEFLNAISNLME
                     DDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCISNTELDFSLHPDDIK
                     EIIKNDVLTKQSIDELLDIGLSEESIETIYDYFSDSTDNGSNIRLKKLISQKENITIK
                     NNDYFKLLQENNELKEKNEKLENTLKEIKKLLTKI"
     gene            11951..12151
                     /locus_tag="KRL22_002513"
     CDS             11951..12151
                     /locus_tag="KRL22_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1272986.1"
                     /translation="MGINLKIFRIKKGLKQQELADRVGISRYYLSNLETGKANNPSND
                     LMIKLSRALDTTVEELFFSKED"
     gene            12155..12469
                     /locus_tag="KRL22_002514"
     CDS             12155..12469
                     /locus_tag="KRL22_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272987.1"
                     /translation="MKENNNLEVLKTLQATLNIIVKNEEEAQEKKQGYKIIENAKRNK
                     AELITCKEASKLYPIGESKFRQLCHSKNKGFPCIWINNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            12491..13234
                     /locus_tag="KRL22_002515"
     CDS             12491..13234
                     /locus_tag="KRL22_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272988.1"
                     /translation="MSNKGWIKLYRELLDKSIWKDIKPERKVILITLLLMASHKENHV
                     FIDNKKIKIKFGQFISSYSKIAERCGKGVSYQMVRSCLLVFKNAGFLTYETTNKYIVI
                     TIENWELYQENIENQQPNQQTINNQSTTIKNIKNENNIIYSEIISKFNSTCIELSKVK
                     KLTDTRKRRINSRIKEYDKETVLEVINIVSKTSFLNGNNNTGWKANFDWIMNSSNFTK
                     ILEGNYNSKEIVINKETGIYNPDDSQLKW"
     gene            complement(13940..15853)
                     /locus_tag="KRL22_002516"
     CDS             complement(13940..15853)
                     /locus_tag="KRL22_002516"
                     /inference="COORDINATES: protein motif:HMM:NF020926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1998 domain-containing protein"
                     /protein_id="HBH1272989.1"
                     /translation="MSIKLDDKTHNLRINQATSVFGPGAMLDFIDQTLMTAHPNYWTN
                     TIKIQDDRLQATLRVNELRTPPTIDDRSSVPFVRFPRWYFCPKCRKFMPIEDWEKLYK
                     NAHKDKPMKIPICLTCSTKKSTKQLVPTGIITICEHGHIDDFPWVKWVHFRNKSGRKE
                     ICENPQILMKTGKSNLGLEGIELECSCGAKANMKGAFMRLKSSKSNDYGVPSEYKEMF
                     KCSGNSPWYNKKVNKCTKYSFASQRGASNVYYPKIESSIIIPPYSDTLNSKVLSSKGY
                     DTFKKFLDRAIKKNKLERFMDEDFEDFASDIAKETGFDTDKVSIVLKDLLPFEDSSPS
                     TTTRNQYREEEYEALIGNIDAKSKKTNDFTIEEQNLSDYDIPNFSKIVLVKRLREVRA
                     LTGFSRVNPPDNNIFGEEDIDDSCNDTKVISLRSRDCKKSFYPASEVRGEGIFIEINN
                     DMVKSWISSNPKIQDNASILNSRYNKDINVNDKAYRKITPKFLLLHTLAHLIIRELSF
                     VCGYATSSLRERIYCNNSENEKVMSGILVYTASGDSEGTLGGLVRQGMHDSLPSILNS
                     ALNRALWCSNDPICIDSTGQGRNSLNLGACHSCTLLPETSCEEYNLLLDRSMLIGDMD
                     NRDIGFFKNLILI"
     gene            complement(15855..19382)
                     /locus_tag="KRL22_002517"
     CDS             complement(15855..19382)
                     /locus_tag="KRL22_002517"
                     /inference="COORDINATES: protein motif:HMM:NF012493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBH1272990.1"
                     /translation="MNCSELRDKTLDLVRKELLGPGSEDLCENIKYEIITDSPIERYS
                     TGILYPLNNNIDVSNTSEYDGEDNVFTSDDTQNELDRAISMSNETLPSSMGMTFFLKK
                     DAEVINFRVNYATYRNALYTDCHVKYTGDDFYSSNTINEYVELRGSFLYLKQKLTSEK
                     VYNLLKKHDLLDNAEAKFVLYKLANQCPDDENKTGGYVRVPHENLIVSIDMDKNYIKK
                     PISKDLDIVLSKRIYSNDFVSITCMLVNSQSGPKKYNNTIFQPELMVLAEDNNDLEFI
                     DIFTAGSVNTFKKLDSEEISLDLLYRNKKTFATGHGVAIDQDIQNDALIKLCTEFIPH
                     FEVPKLDFNVDELSDVSRELLSMKNLSDISDLSKDKKIYFLYKFVDAYDIWIDDLEED
                     SKDLSDVFKDVAYEHIKNCRDTKSRMLEGINLIKSNDEVYRAFSLMNRAILMQRCHSI
                     HITDRLPGSNNLDYIDYSNDNSAWRPFQLAYILTCLSSIENPDSKHRDLVDLLWIPTG
                     GGKTEAYLGLSAFTIFLRRIRNKENGNGTAIIMRYTLRLLAAQQFIRASILICACEII
                     RKENKSELGKKEISIGLWIGSDQTPNFNHEAEEMLNNLTGNNIKFRSSINSEYELDNL
                     KSKYNKFQLLKCPWCGTKLVKEWDKTSKKAVGDWGYRIKSRPKKFYLCCPEEDCSFED
                     MLPIQVVDEEIYNNPPTLLFGTVDKFAMITWTTEVASLFALDDDNSNLSPELIIQDEL
                     HLISGPLGTMVGLYETALDAMCSYKGIKPKIIASTATIRKAQNQVKNLYNRNVAQFPP
                     PGLTSSNSFFVKEMPLSKKRGRLYVGVIPSGKTQVTVEVRLMSALLQRLKMMENVELN
                     LLDKYWTLVSYFNSIRELGKCSTLLNDDIKDNMERLCKRVSAHPYQSLRNLNEQRELT
                     SRLTSTKINTTLDELSNTLTSNNLTVDTLLASNMISVGVDVDRLNLMVVVGQPKLTSE
                     YIQASSRVGRSNEGLIFTLYNPTKTRDRSHYEQFFSYHQSFYKFVEPTSITPFSEPAR
                     ERGMHAVLISMIRHILGLQANDLASRFSKNMDGVEDLKNFIIDRSIDIFRENNQNADD
                     NIVNEFKSEISSELDIIMDLWHDKAQISDKDNLLHYYKRPSKFDNKIYNNLLIPYDKD
                     VITNEKQTLNSMRNVDKQCTVEIIELEEN"
     gene            complement(19400..22018)
                     /locus_tag="KRL22_002518"
     CDS             complement(19400..22018)
                     /locus_tag="KRL22_002518"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272991.1"
                     /translation="MLTTNIHYILDNDICEIYFNKQRLTNSKYYQDNINVLNYIINEK
                     NNNLIINYNDKYIYAIYLLNIAINSYLNNTLNPNNHILTKLDKGMPLLYKGQIVIFKN
                     INNTHITLGHKNKTDTTLIPIDSAYMLITYNGHLEVNSMGKTPASKTFQTKNVLSSLG
                     FSDLKNMTGVINDSTLIILPCKDDISDLVSNIKIKDINNTYKFTELFPCSYISSTGAE
                     TDYPGNHAKQIPLLKFTTNISSAFEIIKSDKSIKNVFIIGDYPIYKHINDFERILNRK
                     RIESVNIVTSNSNISNILDLPNIDNLNIYSWSKDVLLTYSQDFENTSTFQKLWLDKLI
                     NKNICTTSVDSNISDLIHQARKSLYYISKYDFDISIKNSLMMCSYSLLKILENTPFNL
                     DFLEETIKLLNLNIATPSAKLENIKYLISSTSPDLELSALFDDVIVKFERIINELSDN
                     NTKFNTLNKLVSSYKYKTFTPNTPVILLQKQYEAIILKNLLKSRNINLQVISAEKFKD
                     SKTIKNLIMFGFYDLKYLDILNSDLIINITLYLYNSELSKYNYYMNQINSARNKIEKN
                     NKIYNLLDIKPFKPTYETNKLEAYSTDSPISDDDSMDEYISNYKFDINLNEIILSLSI
                     NQGIYNSKKEHVTSFMISDNNEYIFCTKKAIAYSIDWDKKSVRKKKLSEAKVNDWFLF
                     VDDYLNEEGELVINVIQKLLELNLLPSHYLDDYKLTNSWKSELKNYISYSKYNYNDVS
                     NSLAVLGEKINPITIKNWVTNKRLIGPIYLKTFEKIFKVIDSKLDHTEVYDATKSIRS
                     LHTKIKKSIDTFVSDNFFSSKSDIIKDEVSAVVLSMLGNTNDYVTPVQIREIHSCDKY
                     LSPHLVNKVLDLYSVY"
     gene            22330..23955
                     /locus_tag="KRL22_002519"
     CDS             22330..23955
                     /locus_tag="KRL22_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012100074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBH1272992.1"
                     /translation="MYNVIDLFAGAGGLSLGFEMTKKFNMVAFVEKNDNAAKTYLENH
                     PSVKRYCDIKRLDFQDILNSVDKIDVVIGGPPCQGFSNANRQKRKIINGNNELVKLYV
                     DAIDKLKPNVFVMENVKTISSNKHSFYLTKKDKNHIINNLKLNIYNKDSVLYDRTEYI
                     NELFNIISIEDIESYIISNIDLKNLKIIIKKKKDICDYLNKISNYKKVKSTIEKLETR
                     GKMPKWYLELINKVKNILENMLYNRNLSDEQIFYLNLFLDIQNLFLGIYELKSESVIF
                     ENTLDDNKIIAKMDTYIIIDYINASFEYLGYVLNGSALNSIDYGVPQNRERFVLIGAK
                     KDFLKNKKIETPKPIVGENYVTVRDAIGDLAEYEASKGSMDYCFEKNSNNIEKDFYRK
                     IILDSNKIYNHVCTDTRNIALKRFEYINQGNNFHSLPDELKGTYADPERTQNTIYKRL
                     VYDKPSDTVVNVRKSMWIHPIKNRAVSAREAARLQSFPDSYKFLGTKDSVYQQIGNAV
                     PPLLGRVVAEKILNLFNDEPNEYLRDVFEALDG"
     gene            complement(24955..25527)
                     /locus_tag="KRL22_002520"
     CDS             complement(24955..25527)
                     /locus_tag="KRL22_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HBH1272993.1"
                     /translation="MEKLVKILINIICIIALTFSSLSIYIKLSEYKKADEVYTELREN
                     TINNSKHQELYDKNNDYRFWLKINNVNINYPVVQGYNNDFYLTHDFYKNYLPLGSIFM
                     DYRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEVFFKENNLVEINYKVQTYTYEIFS
                     VYTADLINRDYLSIHFNNNDEFKYSLNYIT"
BASE COUNT         9345 a         3288 c         3458 g         9440 t
ORIGIN      
        1 ctataaaatt atttctgggg gtgtatttat atatggaaat gaaaatagca gtatccaatc
       61 ttagtaaaag atttgggaaa aaacaagctc ttgataatat aaatcttgaa atcgacagtg
      121 gtatgtttgg tcttttagga agaaatggag caggaaaaac cacatttatg agaattttag
      181 ccactttatt atcaaaaaca gaaggttcaa tacatatgtg tggagttcct attgagaata
      241 ctaaggaaat tagaaatatg gttggttatt tgccacaaga tttttcaatg tatcctaaca
      301 tgacagtata taaagcaatg gattatttag cagttttatc ggatatacca ctaagaaaaa
      361 gaagaaaaat tatagcaaag ttattaagca aagtaaacct tactaattat caaaatgtga
      421 aagtaaaatc tttatctgga ggtatgaata gaaggcttgg gatagcacaa gcattaattc
      481 ataatcccag agttttaata gtagatgagc cgacagcagg tcttgaccca gaagaacgta
      541 taagatttag aaatttacta tgcgaaattg caaatgatag aatcgttatt ttatctacac
      601 atattgttgg agatatagaa gctacatgtg aaaacgtagc tatattgaat agtggaaaag
      661 tcatatacaa tggctcaaca gaagcattag caaaactagc tgaagggaaa gtatatagta
      721 ttgaagtaga taaaaaagac attgaaaata taaaaagtag atttatagtt ataggaatgt
      781 tgactcatgg tggaaaggct atacttagga ttatatcaga tgataaacct tttgagacag
      841 cagtaaattg taatccaact attgaagatg gctatatgct tataatggga ggagataata
      901 tatgaatcta tttataaaag aatgtaaaaa tatattaaag agtatggtat attatatttt
      961 tattgtagtt ttagtttttt tctatatttc tcaacttgga agttcagttt caaatgatgt
     1021 aagtaaaaat attcctaatg atggaaatcc attagttgct ccacaaaaag tagagaatat
     1081 tgaggaatat tactctgtac acaatcaata tccatatggt caaaaagaat ctatgaaaac
     1141 agaaaaagtc atttcaaatg caactataaa cctaattaga gaatatcaaa aaaacacata
     1201 tacaacgtat ccaacaggtg tagttaagta tataaaatta gaccaaaata aaacgaagac
     1261 catagaaaaa tatatagaag aaataactgg taaaattatt agcgaaataa attcactttg
     1321 gaaaactgat gaaagtataa aaatagatta ttctaaagta tctcttgaaa gatttgaaga
     1381 aataatgcaa agagtagacg acattttagg aggagggtct gcatatgctt ttgacaagtt
     1441 acaaagattt ggagtagttc cagttaccta tgatgaagct atgaaaaatt acaactatac
     1501 aatacaaaaa gataaagtta gtaatgggta tgcaagaatt ttttgcgatt atataggtat
     1561 agttttaagt atatttccag tatttgtggc agtttttatg tcacttaaag ataagcgttc
     1621 aagaatgaga gagattattt attcaaaaca agtatcttca tgcaaaatag ttttatcaag
     1681 atattttgca cttgtcttta tgatgatatt gcctgtatta attttaggta tgaaagattt
     1741 acttcctttg attttctttg ctaaagataa aggtatatct attgataact tagcatttat
     1801 aaaatataca ttatggtgga tactaccaac tcttatgata gttacagctg taggaatgag
     1861 tattactata ttaacagata caccagtagc aattattgtg caattaattt ggtggcttta
     1921 cagtataaat tctacaggac tcaaaggtga ttattcaaca atgggactaa tgataagaca
     1981 taatagtgta ttaaatgggg atattattat acaaaacttc aatcaaatta tgattaatag
     2041 aattgtgata agcttgggag cattggtgct tgttttgtta gctatattct tatatgagca
     2101 aaaaagaagg gggaatcttg atgtttgggc aaagttttca aaactgttta gttctaataa
     2161 aagaaaactt caaattaagc actttaacta atttaatatg ttcaattata ttgctatgta
     2221 tgattcctct aatacaagga gtagctaatt tagacagaat ttcaacagct atatgtttag
     2281 aaaattatgt tgcaataata gggatagtaa tgttggtacc cgtattttcg ctagagcaat
     2341 caaaagaaat tgatgagata gtatcttcaa aagcattatc tcaagttatt gtacaattaa
     2401 ttaggatact gatgtcaatt ataggtatag tggtattaat cataggtttt gtaaatgttt
     2461 taatatatct tggatgtaat tttccagtag ttgagtatat tattggaagt ttcgcatcag
     2521 ctatgtttat aggaagttta ggaatgtttt tctcaaattt atttaataat acaatcatag
     2581 gttatatgat atctatagga tatttaattt taaatatgat gactaaaggc aagtatgttg
     2641 gaaaattttt tataatgtct atgagtcaag gtagttttga tgagaaatat tggctgatac
     2701 ttggaagtgt tgtgttgata attgcatctc tcttaataaa accagtaaaa aggaagatta
     2761 gataataaaa tgagagctta gataaaataa aggtaataca aataaaaagt acatttatga
     2821 aatataaatc tatttttata tacacaaacc tacttacaat ctctttatat atgtagatag
     2881 atttatatat ccgtagtata aaatatatat gtatacaaaa ttttatcaaa agctctcaaa
     2941 tttatatttc aaagacactt attgctatgg cctacacata tgtatttttt tattttaatt
     3001 gttgtattaa caataagact attgttataa actattgata cctcataaca aaaaattctc
     3061 catctcttaa atgcgttttt tgtaccttag tctcaactat tttaaatcct tgagactcat
     3121 aacattttac agctctcatg ttccaggttc ttacatttaa tacaattggt ttagtactat
     3181 atttatttct acattcttgt aatcctaggc taattatttc tttaccaatt cccattccac
     3241 aataattcgg tttcatacca ataccaaaga atacagagct tccttcatct aataagttta
     3301 taaaacctat caattcttta ttgtcattta taaaacttat aaaatttttt cttttatctt
     3361 cttttgctag tgaaaaattc ttctttttaa tttcctccca tggaggtaga ttgtatattg
     3421 aatatttacc ttcatatttc caattagtaa cttcaatagc atgttcttca gtaaatttaa
     3481 ctttatttaa attcatatgt cctcctatta aaatatttaa ggtaattaat ggtattttaa
     3541 agttttagaa aataagtaaa actatttata tttatccata aaatctttaa aaattttact
     3601 aacaattctt gtaccctgta ctttttattg gattcacaga agactataaa ctaattttga
     3661 atcaccttct aattcaaaaa catcacgata tatataattt cttagcttga ttaaattctg
     3721 ttaaatccgt ttcttatagt tgtataatca acatcaatat ctttatgtgt attagttaat
     3781 ttattggttt taggaactta ttattaatat attgtatttg ctccaataat ccaagtagta
     3841 ggtaaattat aggcaaatta tcaaatgtat atctatccat gcttaaactt tagagataca
     3901 ataactacta aattagtgtt ctagtagtta caaaaaagaa tctttaaaaa tattaattta
     3961 acttatattt tttaataaat tttctaaaat ttaataagtt aatttaatta tagctctaaa
     4021 tgatattttc tacagatata attttaaaaa ggtgtgtata agaacaaatt cacttaaatt
     4081 tttaaaatca aataaagttg aatctcttga ctaccttgat tgttttatga aattaatata
     4141 gatgtaaact ttactattaa aaaaatacaa gattttagat aagttaatgc taattataaa
     4201 taataagata agaaatataa tatgacataa gggctaggaa taagataaat ataatcaaag
     4261 aataagatat gagaataact accaagagaa atcattacct taatatgttt ataaatgtta
     4321 gactatgttc ctaaattgaa ttttatatat caagtataat aactttacag aatgtggaaa
     4381 tttttattta aagaatacac ataaatattt ccacactctg attttataat aataatctaa
     4441 taaaatttat agtgacttta taaaatcaat aatgatttaa taaatattta taaaacaact
     4501 atttttgctt agaaacttta ttattcatat tatcattagt aggcattgct ccaaaactta
     4561 gtttttcata cattacttga gttggagcta gccaaactgt accactacca gtaaatgtat
     4621 ttaagaaacc ttcaccattt aaagcagaac caattaaaga tttatctgat tttgtaacag
     4681 aaaaattaac accagatgtt cttgctattg caaagttacc atctaccttt aattcttcac
     4741 catttttcaa ttcatactct acaatttcac tttgaggtac aacacattcc agaacgatta
     4801 caccagtacc acttaattct atttggaaga agccttcacc accaagtaaa gcagatgaga
     4861 agttcttttg tgtaaatgct tttacttcta ttgtatcaga gcaacaatag aataatcctt
     4921 tatcaacaat tatagaatca ttatcaagac tcataaataa ataatgtcta aaagaaggtt
     4981 ccaaataaac ttctccagta cctttgtata caggtttcat cattgattca ttagtaagtg
     5041 ctcctgatat tcctttttta aaaagacctc caacaccacc aatcttagtt tcagaagata
     5101 tatttccttt ataatagtat aatgcaccag cttctgtttt tattgatgaa ttatttaatt
     5161 ttatcttaat ttgtctagct ttcaaaccag cttctctagc aaaatataat cccattgcca
     5221 ttaatgggct agaagctccc tcaagttttt caaattctaa tatctcaaat tcgcttttgc
     5281 catctgatgc attttctaaa atttttactt ttttgcttaa atccatacaa atttctcccc
     5341 actatgataa aatttatctc taaaatatta taagatataa ctctatatta catttttttt
     5401 gaaaaaatcg ctactttatc atcaaatttt tacatatttt taagaagttt ttgaaatgtt
     5461 tagatttaag ttaagttatt taaggatgta tagttatttc aatagacatt ttgagtatta
     5521 tttatcattt gtgggtatta tattttatgg gcatgttaaa attatttaga agatagaaga
     5581 tagaagatag aagatagaag atagaagata gaagatagaa gatagaagat agaagataga
     5641 agatagaaga tagaagatag aagatagaag atagaagatt tataatatgt aatatttttg
     5701 ttttgaaatt tataaattag tattactggt tagagttagt ttagtattaa gtatattcga
     5761 agtagttttt tagctatttt catacattta tattacttaa ttatatatag cctaactaac
     5821 ttaatatatc agtgaaatat tgactaaaat gcctaaatat gttatcatac aagttagtca
     5881 aataatttgg caacattaaa tatttagtaa atttctaaca tttatggaac aaatttctag
     5941 caaagaaggt gagatttata tggctggtaa aaaaatatta gcaacaaaca aaagagcaag
     6001 acatgaatat tttatagaag aaacttatga atgtggaatt gaattaaaag gaacagaagt
     6061 aaaatcaata agacaaggca aagttaacct aagtgatgga tttgcatctg tagataatag
     6121 cgaagtattt ttaaaacaag ttcatataag tccatatgag caaggaaata tattcaatgt
     6181 tgattcttta agagttagaa aactattact tcataagcat gaaataagaa agcttattgg
     6241 agcaactact ataaaggggt attcacttat accacttagt ttgtatctaa aaaacggtaa
     6301 agttaaagta gagattgcct tagcaaaagg taaaaaacta tatgataaac gtcaagatat
     6361 ggctaagaaa gatgcacaaa gacgtataga aagagaaatg acaggtaagt attaaactag
     6421 ataaaactgt attttttaga ataaaattct ttattatcta gaacataaca ttgattttta
     6481 ttcttaaaag tattatatta tatatacatt aaaaatttaa taaaaatggt gataaagttt
     6541 gagaaaagtc tactggacta taaactactc aagggggcgt aaaggtttcg acgtgggttt
     6601 ggaacttgag gctgcatgtc gtgttactct gggtcacgta aaaactgggg aactttaaaa
     6661 taaacgcaga cgataatttc gcgatagcag cctagttgct gctcgtccct cttagtcctc
     6721 ctgccgacta agactggacg tcattatgca gggaactact ttaggggtgt ctcgacttga
     6781 agtagattaa ttgggactgg ctaagcatag agcctgccac ttggcgctat gtgaggtgag
     6841 atattagtga agttggctaa gcatgtagat gcagcaagga aaagatttgc ggacaggggt
     6901 tcgactcccc tcgtctccac caattttgaa aaaagaatga tgaaatactt ggaaatacta
     6961 gtctttgttg actagtattt tttattttgg agaagaaatc caccaaccgt accccaacca
     7021 cagaaaatga ggtttttttg ggggtatatt ggggtgcatt taggctgtat aaaaagtttt
     7081 tatttgttta ttattttatt tgtttattat tttatttgtt tattatgata ataggtaaca
     7141 tagaatttta atatctactt tatgatataa tatttttata aatgtaagac agtttaagtt
     7201 gttaattagt aaaaatatat attatataag cttgatagga gttgaggttt gtaatggatg
     7261 aaagaaaact agaattttct attttttgca ttgaagcttt agcagaaaaa ttgaatatag
     7321 attcagaagg agtttataaa cttcttaaac atgatactga tattttagat aactatataa
     7381 taccttgcta tgaagcacta cattctcaaa gtaaaggtta catagtggaa gatttaatgc
     7441 aagtacttaa agaaaagggt gtgatataat gattgtatat catggttcat attgtgtggt
     7501 aaagacgcct agtattacct tttcaagaga ttctttagat tttggaaaag gattctatgt
     7561 aaccagtata aagacacaag caattaactg gacagagcgt tttaaaaaaa gaggtaaaaa
     7621 agcatattta aatagttatt ctttagatat tgataaatta aaagaaaact gcaaggtaaa
     7681 aatcttcgat agttataatt tagaatggct tgattttata atagaatgta gaaatatgag
     7741 tgatatatat atgaaatatg acattataat aggtggtatt gctgatgata agatttacaa
     7801 tacaatagaa ctgtatcaag ataatcttat tgaaaaagat gaagctttaa aaagattaaa
     7861 atactataaa ccaaatgaac aaatatgtat aaccaatcaa aatgtaatag ataaatattt
     7921 aaagtttagg tatgaagagg aggtataatg attatggaag caaataaaac attattacaa
     7981 atactatata aaaaaatcat attagaattt tccaaacaaa caggtaagag cttggaagaa
     8041 agtatggatt atttatatac ttctgaaaca tataaactta taagtgaggg tgtatcagat
     8101 atgcactgta agggtcatat atacttggct caagaattaa tgttagaaaa tggattaatg
     8161 taccataagg gctatccaag ataaataatt aaaactagat acgaaataag gatacaatat
     8221 aatataaaat taatttgtat ccttattttg attttgtaat taactatatg aaatcacaat
     8281 atttatatgt atttgatttt tacaatgaaa atattttatc caacttttct acagcttcaa
     8341 ctttcttatc ttccataact tgagtatata tattcaaagt tattgatata tcataatgac
     8401 ccattaaaac ttgtacagtt ttaggaggaa catcattctc aaaaagtcta gtagcataag
     8461 ttttcctaag accatgaaac tttataggct ctatatttaa gctatttaat atagacttta
     8521 aattccttaa aggtctttta tcatctatag ggatgcctaa ttcattgcaa aatacataat
     8581 tattatttat atataattct ccagccttta atatatctgt attttgattt actttatgct
     8641 ctttcaattt atttaaaaca tcttttggaa taggtacagt tctgtaagaa tttgatgtct
     8701 ttggcccttg ctctaatact ttaagctctc tatttccagt tttatctata aaatatgttc
     8761 tttgaagagt tcttttaact gttaaattag actttttaaa atcaatatca aaccatttaa
     8821 gtcctaataa ttctcctaat ctaagtccag taccaagagc aagtaaaaat aatacctcta
     8881 atttatgccc atctatagct tttataaaac tcttttgttg ttcaagagtc aatatttcaa
     8941 gtttgttttc ttttttctca actggtatat ttaccatagt acaatagtta cgttgtataa
     9001 gaccttgttt ttcagcttct gataagcagg ttttcagttt agtgtttatt tgccttatag
     9061 taggtatact tttattggaa tcaagcaatc tattgtaata tttttgtatg tgagatactc
     9121 ttaagtactt taatttaaca ttgcctaaat cagtatcttt aatataatta cgatagatgc
     9181 tttcatatct ttcaaatgac ttgggtttta aatcttttat tctatattca aataaccaat
     9241 tgtaaaacca atgctctaaa gttattttat catctgaaat atcagagctt aaataatatt
     9301 gttttttata agcatctaat ttatctttaa cttccttttg agtcttacca taaaattctt
     9361 ttctcagtgg tttaccatct tcattatagc caatcattat acgggaacgc caaccatctt
     9421 tatattttcc gatagagcct tctccattag ctcttttagt tgccattttt aaacagctcc
     9481 ttatatgatt tatagttata tccatcaaag aatgtaatac atttctctaa taagaatttt
     9541 ataacttcat cagcttctag tgtttcatag aagtttagca ttaatgtgtt gtactcttgt
     9601 ttatgtttag ctggtattga tagaactcct atatcattat ttataagtat taggtttgag
     9661 gtaagtctag cagttctttt gttgccatca tagaagaatt ggcaatagga caaccataaa
     9721 tttattatta tagccttttc taatgggtta gttattttat ttatgatatt tatgtcattt
     9781 acaaataaat catttaatag agtggcttct atgcattcat attgagtagt accagctata
     9841 cctatattac catttctgaa atctccaacg attagagctt catcttttgc aactatttta
     9901 tgtatagagc aaattgtatc tttatttaaa gataagtttt ctttgttact taattttatt
     9961 acataatccc atgatgattt tatatttagt atttgatttt ggtcacttaa tttatgtccg
    10021 cctacggtta taccatcaag taatgtttgt acttctggga atgtgaaggg gttattttct
    10081 aggttaccca tatcatatac aaattcactt atcattcttc taatgtatgt taaagtatat
    10141 tttttatctc catgaggtat attattaggg aatttatgtg tgtattttgg tatatatgat
    10201 ttattcatga ttttagctcc tttcatatct aatttttatt tattaactat gaatgtataa
    10261 aagttaatag gtaaactcat attttgaaaa tgtgcaatac taatattctt catcctcatc
    10321 ttcaataaga ccattagagt tttcttgtat aaaattttca acaagaccat ttatcaccca
    10381 atttagattt ttggagaagt ctttgaagtc agagaagttt aggttaattg gttttattgt
    10441 atctgcatta tctgtaattt caaacttttt tttatagtct gtttttatat cataaccata
    10501 attttctaat atgtgaatta ctaaatccaa ctctttatca aatactttta aattaatatt
    10561 attatttgtt aaagtatcta aatcattttc ttcaacaatg agtttattta tagcaattga
    10621 taaagcagta gctatttttc ttatcatatc taaactaggc attctttgat tttgctcata
    10681 tttagctata gcatgaactg aacaaccaat cttgttggct agctcatccc ttgacatatt
    10741 tatcgatttt ctatattgtt taatcttttc tccaattgta ttattcatca taatttcacc
    10801 ttaaatatat catcaaacaa tgattgtact tctaaacatg taaaggagtt attttctaga
    10861 ttatcccata tcatatacta aattactcat aactctctta gtgtatgtta gagtatattt
    10921 tttatctcca tgaaataaat tagtagggga tttatatgtg tattttagca tatatgattt
    10981 attcataatt gtaactccat tcatagtttt ttatcattgc tttagatagt attgatatta
    11041 ttttatattt tagttagtag tttttttatt tctttaagtg tattttcaag cttttcattt
    11101 ttttccttta gttcgttatt ttcttgtaat aatttaaagt aatcattatt tttaatagta
    11161 atattttctt tttgagatat taattttttt agtcgaatat tacttccatt atctgttgag
    11221 tcactaaagt aatcatagat tgtttctata ctttcttctg atagaccaat atctaataat
    11281 tcatcaattg attgttttgt aagaacatca tttttaataa tttcttttat gtcatcagga
    11341 tgtaatgaaa aatctaattc agtattagat atacaatctg aaagtatcca attataaact
    11401 tgattttcat ttagttctaa tttttcacca agtttataat attggtcttt atcagaccag
    11461 gcacctagca ataaacttga ggtaattcta atatcatctt ccataagatt tgaaatagca
    11521 tttaaaaatt catcaaaaga atagtattct tctgggaata aagactgtaa aaggtataaa
    11581 acatcttcat tagtcattac ttcattttca atatcaaaat aaaagatagt cttttcaatt
    11641 ttcaaagctt tagcgagttt tgataaggta tctatactag gtattctttt atcattttca
    11701 taatttatta gagcatttct tgagatgcca ctaatttcag caagttgaat ctgcgttagc
    11761 tctttttgtt ttcttatctt ttttaagttt tttccaattt gcaatattat cacctcgtat
    11821 aaagtatatc ccaaaagtac acaaatgaga acagaaaaat aatatattct tattaacagt
    11881 acacatatat cgacattata attaaaatgt aaagtttacg aatgtaaact agaaaaaagg
    11941 aggaaaaagt atgggaatca atttaaaaat atttaggatt aaaaaaggtc taaagcaaca
    12001 agaactggca gatagagttg gtatatcaag atattattta tcaaacttgg aaacaggtaa
    12061 ggctaataat ccaagcaatg atttgatgat taaactatct agagctttag atacaacagt
    12121 agaagaatta ttttttagta aggaggatta aaatatgaaa gagaataata atttagaggt
    12181 tttaaagaca ttacaagcca ctttaaacat tattgtaaag aatgaagaag aagcacaaga
    12241 aaaaaagcaa ggatataaaa ttattgaaaa tgcgaaaaga aataaagctg agcttataac
    12301 atgtaaagaa gcatctaagc tttatcctat aggagaatca aaatttaggc agttatgtca
    12361 ttctaaaaac aaaggattcc cttgtatatg gataaataat cgagtataca taataaaaaa
    12421 taaattagat gattggttta ttgaaaatgc aaatggtatc aagttatagt cttaaagtag
    12481 gtgtttgcaa ttgagcaata aagggtggat aaagctttat agggagttgt tggataaatc
    12541 aatttggaaa gatattaaac cagaaagaaa ggtaatatta ataactctat tacttatggc
    12601 tagtcataaa gaaaatcatg tttttataga taataaaaag ataaaaataa agtttggaca
    12661 atttatttct tcatatagca aaatagctga aagatgtggt aaaggagtta gttatcaaat
    12721 ggttagaagt tgtttgttgg tttttaaaaa tgctggtttt ctaacatacg aaacaacaaa
    12781 caagtatata gtaataacta ttgaaaactg ggagctttat caagagaata tagaaaatca
    12841 acaacctaat caacagacta ttaacaatca gtcaacaaca atcaagaata taaagaatga
    12901 aaataatatt atatatagtg aaatcataag caaatttaac tcaacttgta ttgaactttc
    12961 aaaggtcaag aaactaacag atacaagaaa gaggagaata aattcaagaa taaaagaata
    13021 tgataaagaa actgtattag aggttataaa tatagttagt aaaacaagtt ttctgaatgg
    13081 aaataataat acaggatgga aagcaaattt tgattggata atgaattcaa gtaattttac
    13141 taagatacta gagggaaatt ataatagcaa ggaaattgtc ataaataaag agacaggaat
    13201 atataatcca gatgactcac aattaaagtg gtaaggaggt tatattataa ataattcaaa
    13261 caacttaatt aaaaatacag aagcagagca atcaattaaa ttacactaag ttagttataa
    13321 atctttcata tatttgtttt ttaagtatct ctaatatcgt ttaaattaca ctaagttagt
    13381 tgcagatata ccagaaaata tatataaaat tatgcgtaaa ctatattgtt atgagtacaa
    13441 ataatattta cctattcatt aaaaaactta actaagaatt taatttatat tattgaagta
    13501 tcaataattt tggaaagtag aaaattatac cccaataata ccccaactac aaaaatagac
    13561 aataaaaaat aaccagaaaa attgcttcaa catcatgacc aaatagccat atacctatac
    13621 ttataaaaac caacaaaaca atcaaataac cacttataaa ttctcctcgg tctccaccat
    13681 tggaatccac gaaaacatat tgatttaata gttaatatgt tttttatttt gaaaaatcat
    13741 atataatata aattaatagt ttatttaaaa atttcagtat gagcacaaaa ttatataatt
    13801 attgggaatt agttataata agtaatttct agtaagaatg atttgcaaaa aataataatt
    13861 taaatacaaa aaactaaagg atagaagtca taaaattaac ttttaacctt tagttatata
    13921 aataaaaaat tagttattac taaattaaaa ttagattttt aaagaaccca atatctctat
    13981 tatccatatc accaattaac atgcttctat caagtaataa attatactcc tcacagctag
    14041 tttcaggcaa taaagtacat gaatggcatg ctcctagatt taaagaattt ctaccttgac
    14101 cagtactatc aatacatatt gggtcattag aacaccaaag agcacgatta agagcactat
    14161 ttaatataga tggtaatgaa tcatgcatac cttgcctaac taatcctcct aaagtacctt
    14221 cagagtcacc acttgcagtg taaactaaaa ttccagacat aactttttca ttttcggaat
    14281 tattacaata tatacgttcc ctaagtgaag aggtagcata tccacaaaca aaactaagtt
    14341 ctcttataat taaatgagct aaagtatgta gtaataagaa tttaggtgta atttttctat
    14401 aagctttgtc attaacatta atatctttat tatatctaga atttaaaata gatgcattat
    14461 cctgtatttt aggattagat gaaatccagc tttttaccat atcattattt atctctatga
    14521 aaataccttc acctctaacc tcagatgcag gataaaaaga ttttttacaa tctctagatc
    14581 ttaaacttat aaccttagta tcattacagc tatcatctat atcttcttca ccaaatatat
    14641 tattatcagg tggattgact ctactaaacc cagttaatgc ccttacttct ctaagtcttt
    14701 ttactaacac tattttactg aagtttggaa tatcataatc agatagattt tgttcttcta
    14761 ttgtaaagtc attagttttt ttagatttag catctatatt tccaattaaa gcctcatatt
    14821 cttcttctct atattgattt ctagttgttg ttgatggtga agaatcttca aaaggcaata
    14881 aatctttcaa aactatggat actttatcag tatcaaaacc tgtttcttta gcaatatcac
    14941 tggcaaagtc ctcaaaatcc tcatccataa agcgttctaa cttattcttt ttaatagcac
    15001 gatctaagaa tttcttaaat gtatcataac ctttactaga tagcacttta gaattaagag
    15061 tatcagagta tggtggtata ataattgaac tttctatctt aggataatat acattagagg
    15121 cacctctttg agaagcaaat gaatatttag tgcatttatt tactttttta ttataccaag
    15181 gcgaattacc agagcattta aacatttcct tatattcact aggtacacca taatcattag
    15241 atttagaaga ttttaaacgc ataaatgcgc ccttcatatt agctttagct ccacagctac
    15301 attcaagttc tataccttct aatcctaggt tactttttcc agtcttcatt aatatttgag
    15361 gattttcaca aatttctttt cttccagatt tatttctaaa atgaacccat tttacccatg
    15421 gaaaatcatc aatatgacca tgttcacaaa tagtaattat accagtaggt actaattgtt
    15481 tagtagactt ttttgtgcta caagtaaggc aaataggtat tttcataggt ttatctttat
    15541 gagcattttt ataaagtttc tcccaatctt ctataggcat aaattttcta cattttggac
    15601 aaaagtacca tctaggaaac ctaacaaaag gaacagaaga tctatcatct atagttggag
    15661 gtgttcttag ttcattaacc ctcaatgtag cctgaagcct atcatcttgt attttaattg
    15721 tattagtcca ataatttgga tgagcagtca ttaatgtttg atcaataaaa tctagcatag
    15781 ctcctggtcc aaaaacactt gtagcttgat ttattcttaa attatgagtt ttatcatcta
    15841 attttataga catattaatt ttcctccaat tctataattt caacagtaca ttgtttatca
    15901 acatttctca tagaatttaa tgtttgtttt tcatttgtaa taacatcctt atcataagga
    15961 attaaaagat tattatatat tttattatca aatttactag ggcgcttata ataatgcaat
    16021 aaattatctt tatcagatat ttgagcttta tcatgccata aatccattat aatatctaat
    16081 tcagatgaaa tctcagattt aaattcattt actatattat catcagcatt ttgattattt
    16141 tctctaaata tatcgataga tctatctatt atgaagtttt ttaaatcttc tacaccatcc
    16201 atattttttg aaaatcgact tgcaagatca ttagcttgaa gtcctaaaat atgtctaatc
    16261 atacttatta atactgcatg catgcctctt tctctagctg gttcagagaa aggtgtaata
    16321 ctagtaggtt caacaaattt atagaatgat tgatgataac taaagaactg ttcataatga
    16381 gatctatctc ttgtttttgt aggattatat aatgtaaata taagtccttc attacttcta
    16441 ccaactctac tgctagcttg tatgtattca gatgttaact taggctgacc aactactacc
    16501 attaaattta atctatcaac atcaacacca actgaaatca tattactagc taatagagta
    16561 tcgacagtta aattattaga agtaagagta ttagatagtt catctaaagt tgtatttatc
    16621 ttagtagaag taagtctact agtaagctct ctttgttcat ttaggttcct taatgattga
    16681 taagggtggg ctgagactct tttacataat ctttccatgt tgtcttttat atcgtcattt
    16741 aaaagtgtgc tacacttacc taattctctg atactattaa aataagatac tagtgtccaa
    16801 tatttatcca ataaattcaa ctctacattc tccatcattt taagtctttg gagtaatgct
    16861 gacataagtc taacctctac agtaacttga gtttttccag atggaataac acctacatat
    16921 agtcggccac gttttttact taaaggcatc tctttaacaa agaaagagtt actagatgtt
    16981 aatcctggag gtggaaactg agctacatta cgattatata gatttttaac ttgattttgt
    17041 gcttttctta tagtagcagt agaagctata atcttaggtt ttataccctt atagctacac
    17101 atagcatcaa gtgcagtttc atataaacct accatagtac ctaaaggtcc agaaataaga
    17161 tgaagctcat cttgaattat taactcagga gataagttgc tattatcatc atctaaagca
    17221 aaaagactag ctacttctgt agtccaagtt atcattgcaa atttatcaac tgtaccaaat
    17281 aaaagtgttg gagggttatt ataaatctcc tcatctacaa cttgtatagg taacatatct
    17341 tcaaatgaac aatcttcttc aggacagcat aagtagaatt tcttaggtct agatttaatt
    17401 ctatagcccc aatcaccaac agctttttta gaagttttat cccattcttt aacaagtttt
    17461 gttccacacc aaggacattt tagtaattgg aatttattat attttgattt taaattatct
    17521 aactcatatt cactatttat actagatcta aacttaatgt tattacctgt taagttatta
    17581 agcatttctt ctgcctcatg attaaagttt ggagtttgat cactcccaat ccacaaacca
    17641 atagaaatct cttttttccc aagttcagac ttattttctt ttctaataat ttcacaggca
    17701 caaattaata tacttgctct tatgaattgt tgtgcagcca atagccttag tgtatatctc
    17761 attatgatag ctgtaccgtt accattttct ttgtttctta ttcttcttaa gaagatagta
    17821 aaagcagata gacctaagta ggcctccgtt ttacctccac cagtagggat ccaaagaagg
    17881 tcaactaaat ctctatgttt agagtcagga ttttctatcg aagataaaca tgtaagtata
    17941 taagcaagct ggaatggtct ccaagcagaa ttatcatttg agtaatctat atagtcaagg
    18001 ttattagatc cagggagtct atccgtaata tgtatagaat gacatctttg cataagtata
    18061 gctctattca ttagagaaaa tgctctgtat acttcatcat tagacttaat taaatttata
    18121 ccttctagca ttctagactt agtatctctg cagtttttta tatgctcata tgctacatct
    18181 ttaaaaacat cactaagatc ttttgaatct tcttctagat catctatcca aatatcataa
    18241 gcatcaacaa acttataaag aaaatatatt ttcttatctt tactaagatc agagatatct
    18301 gataaatttt tcatagacag taattctcta gaaacatcac ttaattcatc tacattaaag
    18361 tccaatttag gtacttcaaa atgaggaata aactcagtac aaagttttat taaagcatca
    18421 ttttgaatat cttgatctat agctacacca tgaccagtag caaaagtttt tttatttcgg
    18481 taaagtaagt ctaaagatat ttcctcagaa tctaactttt taaaagtatt tactgatcca
    18541 gctgtaaaaa tatctataaa ctctaaatca ttgttatctt cagctaatac cattagttca
    18601 ggctggaaaa tagtattatt atatttctta ggcccagatt gactattaac cagcatacaa
    18661 gtaatactaa caaagtcatt tgaataaatt cttttagata aaactatatc taaatcttta
    18721 gatataggtt ttttaatata gtttttatcc atatctattg atactattaa gttttcatgt
    18781 ggaacacgaa cataaccacc agtcttattc tcatcatcag ggcattggtt agctaacttg
    18841 tataaaacaa atttagcttc agcattatca agtaaatcat gcttttttag taaattataa
    18901 accttctcag atgttagttt ttgcttaaga tataggaatg atcccctaag ttctacatat
    18961 tcattaattg tattgctaga atagaagtcg tcaccagtat atttaacatg acagtctgta
    19021 tataaagcat ttctataagt agcataattt accctgaaat ttattacttc tgcatctttt
    19081 tttaggaaaa aagtcatacc catagaagaa ggtaaagttt cattagacat acttatagct
    19141 ctatctagtt cattttgtgt atcatctgat gtaaatacat tatcttcacc atcatattca
    19201 gatgtattac ttacatcaat attgttatta agtggatata aaatacctgt tgaataacgc
    19261 tctattggac tatctgttat tatttcatat tttatatttt cacaaagatc ttccgaacca
    19321 ggtccaagaa gttcttttct tacaagatct agggttttat ctcttagttc actacaattc
    19381 atatttacct cctatttatt taataaacac tatataagtc taaaactttg ttaacaaggt
    19441 ggggtgacag atacttatca caactgtgta tttctcgtat ttgtacaggt gtaacataat
    19501 catttgtatt cccaagcata cttaaaacaa ctgcagacac ttcatcttta attatatctg
    19561 atttactgct aaagaaatta tcagatacaa atgtatctat agattttttt attttagtgt
    19621 gcaaagagcg tatactttta gtagcatcat atacctcggt atgatctaat ttagaatcta
    19681 taactttaaa tatcttttcg aaagttttta aatatatagg acctattaat cttttatttg
    19741 ttacccagtt tttgattgtt ataggattaa tcttttcacc taaaacagct aaactgtttg
    19801 atacatcatt ataattatat ttactataag atatatagtt tttaagttct gatttccatg
    19861 aattagttaa tttataatca tcaagataat gagatggcaa taaattaagt tctaatagct
    19921 tttgtataac attaataact aattcaccct cttcatttaa gtaatcatca acaaataaaa
    19981 accagtcatt aactttagcc tctgaaagtt tctttttcct aacacttttt ttatcccaat
    20041 ctattgaata ggctattgcc ttttttgtac agaatatata ctcattatta tcagaaatca
    20101 tgaatgatgt aacatgttct tttttagagt tgtaaatccc ttgatttata gatagagata
    20161 atataatttc atttaaattt atatcaaatt tataattaga tatatattca tccatagaat
    20221 catcatcaga aataggacta tcggtagaat aagcttctaa tttattggtt tcataagttg
    20281 gtttaaaagg ttttatatca agtaagttat atattttatt atttttttca attttatttc
    20341 ttgcagaatt tatttgattc atatagtaat tatatttgga taattcacta ttatataaat
    20401 acagtgtaat atttataatc aaatcactat ttaaaatatc taaatatttc aaatcataga
    20461 atccaaacat aataagattt tttattgttt ttgaatcttt aaatttttca gcagaaataa
    20521 cttgtaaatt tatatttcta gattttaata aatttttaag tataatagct tcatattgtt
    20581 tttgtagcaa tataacaggt gtatttggtg taaatgtttt gtatttatat gaagatacta
    20641 atttatttag tgtattgaat ttggtattat tatcagataa ttcatttata attctttcaa
    20701 atttgactat aacatcatca aataatgcac ttaattctaa atctgggcta gtacttgaaa
    20761 ttaaatattt tatattttct agcttcgctg aaggagttgc tatatttaaa tttaaaagct
    20821 ttatagtttc ttctaaaaaa tctaggttaa aaggtgtatt ttctaagatt ttaagaagag
    20881 agtaactaca catcataagt gagtttttta tggaaatatc aaaatcatac ttagatatgt
    20941 aataaagtga ttttctagcc tgatgtatca agtcagagat attagaatca acagaagtag
    21001 tacatatatt tttatttata agtttatcta gccataattt ctgaaaagta gaggtatttt
    21061 caaaatcttg gctataggtt aacagaacat ctttagacca agagtatata tttagattat
    21121 ctatatttgg taaatctaat atattgctta tatttgaatt tgaggttaca atatttacac
    21181 tttctatcct ttttctattt aaaattcttt caaaatcatt tatatgctta taaattggat
    21241 aatcacctat tataaataca ttttttatag acttatcaga tttaataatt tcaaatgcac
    21301 tagaaatatt agttgtaaat ttaagtaaag gtatttgctt agcgtgattt ccaggataat
    21361 cagtttcggc accagttgat gaaatatatg aacatggaaa tagttcagta aacttataag
    21421 tattattaat atcttttatt ttaatattac taactaagtc agatatatca tctttacaag
    21481 gcaatataat cagtgtagaa tcatttatta ctccagtcat attttttaag tctgaaaaac
    21541 ctaaagatga tagaacattc tttgtttgaa aagtcttaga tgctggagtt ttgcccatag
    21601 aattgacttc taaatgacca ttataggtta taagcatata agccgagtca ataggtataa
    21661 gtgttgtatc cgttttattt ttatgtccta aagttatgtg tgtattattt atatttttaa
    21721 atataactat ttgacccttg tagagcaggg gcataccttt atcgagtttt gtaagaatgt
    21781 gattatttgg gtttaatgta ttatttaagt atgagtttat agctatattc aacaaataaa
    21841 tagcatatat gtatttgtca ttataattga taattaagtt attatttttt tcatttataa
    21901 tataatttaa tacattaata ttatcttgat aatacttaga atttgttagc ctttgtttat
    21961 taaaataaat ttcacatata tcattatcaa gaatataatg gatatttgta gttaacattt
    22021 aaatctcctt tagtagttac tattgtttat tagaatagtt tttattctat attataatta
    22081 tattactaaa aaataatata tggtatataa tataaaaaaa gattgataaa taaataaaaa
    22141 atatattatg ttatttattt gaatagatta tccagaagac ataaataaga aaaataatgt
    22201 gtaagtaaaa atattagaat ttattaaaag ctattacaag tataagaaat ttgaaatgat
    22261 tattcaaaaa ttgacatgtg aaaaaaaata tgatatgctg caataaaagt taatgtgagg
    22321 tatgtcagaa tgtataatgt tatagatctt tttgcaggtg caggtggttt gagcttagga
    22381 tttgaaatga ctaaaaaatt taatatggtg gcttttgtag aaaaaaatga taacgcagca
    22441 aaaacatacc ttgaaaatca tccgagtgtt aagcgttatt gtgatattaa aagattagat
    22501 tttcaagata tattaaacag tgtcgataag atagatgttg ttataggagg accgccatgt
    22561 caaggttttt ctaatgctaa tagacaaaaa agaaaaatta taaatggaaa taatgaatta
    22621 gttaagctat atgttgatgc tattgataaa ttaaagccaa atgtatttgt aatggaaaat
    22681 gtcaaaacta tatcttcaaa taagcattca ttttatttga ctaaaaaaga taaaaatcat
    22741 ataataaata atttaaaatt aaatatttat aataaagata gtgttttata tgatagaact
    22801 gagtatataa atgaattatt taatattatt agtatagaag atattgaatc atatattata
    22861 tcaaatatag acttaaaaaa tttgaaaata attattaaga aaaaaaagga tatatgtgat
    22921 tatttaaata aaatatctaa ttataagaaa gtaaaatcta ccatagaaaa attggaaaca
    22981 aggggaaaaa tgccaaaatg gtatttagaa ttaataaata aagtaaaaaa tatattagaa
    23041 aatatgttat ataatagaaa tttatcagat gaacaaatat tttatttgaa cttattcttg
    23101 gatattcaaa atttattttt aggaatatat gagttaaaat ctgaatctgt aattttcgaa
    23161 aatacacttg atgataataa aattatagct aaaatggata cttacattat aatagattat
    23221 ataaatgcat cctttgagta tctaggatat gtattaaatg gaagtgcact aaattcaatt
    23281 gattatggag tacctcaaaa tagagaaaga tttgtattga taggagcaaa aaaagacttc
    23341 ttaaaaaata aaaagataga aactcctaag cctatagttg gagaaaatta tgttacagta
    23401 agagatgcaa taggcgattt agctgaatat gaggcttcta aaggtagtat ggattattgt
    23461 tttgaaaaaa atagtaataa tattgaaaaa gatttttata gaaagataat attggatagc
    23521 aataaaatat acaatcatgt atgtacagat acaagaaata tcgcactaaa aagatttgaa
    23581 tatataaatc aaggaaataa ttttcattct ttgccagatg agttaaaagg aacttatgct
    23641 gatccagaaa gaactcaaaa tactatttat aaaagactag tatatgataa gccatcagat
    23701 actgttgtaa atgtaagaaa atctatgtgg atacatccta ttaaaaacag agctgttagc
    23761 gcaagagagg cggctagatt gcagtcattc cctgatagtt ataagttttt aggtacaaaa
    23821 gattctgtat atcaacagat aggaaatgca gtaccacctt tattaggtcg agtagtagca
    23881 gaaaagatat taaatttatt taatgatgaa ccaaatgagt atcttagaga tgtgtttgaa
    23941 gcactagatg gatagttcaa ataaaatagt gggtattatt cttgtgattc ttatccaaca
    24001 ttaatccacg aaataaggac tgtcgaatga gtaattttaa attgctgtgc gacagttctt
    24061 tttttacttg cttttcatta atttatattt atgcaaaatt tgagcttgaa aacggtcata
    24121 agaaataaag gtataaaaat acaattttaa aatagaataa tttacaaagt gtaagattaa
    24181 aaaatatttt tgcgaggatg aatatacata ctacatttat taatgattat cttatttgtg
    24241 aaacttagaa atactatagg ctaacactac aggtataaac tctgaaagaa tattttgatt
    24301 gcctttgatt agaattcttt taaagttcat actatgtttt atttgggtga aagctcctta
    24361 tgcctgaata cttctattca ttctaagttc acatccttgt gtaccagtga ttctttctaa
    24421 attatcttaa tgccaaaatc ttgttcgcat ttcaaaataa agtcaggtag ctacttcaac
    24481 attttagtta tatttcttca atagtttgtc tccaaacaaa ggtacatcta ttagaaacag
    24541 atttaatttt atttatatca ataaataata tatactttga aacttcatta atatcaccaa
    24601 gataatttat aagttaagct attatatact atcttcacca actacatcct ccatagtttt
    24661 acactttctt aattcagctt ggtaatctaa atctgtaata attatttctc tttgattttt
    24721 catttctttg cctacaaaag tttaatataa atattattcc atacttacca attttacgtt
    24781 caaaaaagac tgtagataag tctgcattta cacaaaccta cttataggtc tcttttttga
    24841 aattaattta gcatgaacta tagtaagagc atctttaaat tcatagttac aagtatacaa
    24901 agttataatt ttatctgaaa tatctacctt tatatcagat ttgtgtactg atttttaggt
    24961 tatataattc aaagaatatt taaactcatc attattatta aagtgtatac ttaaataatc
    25021 tctgttaatt aagtcagcag tatatactga aaaaatttca taagtataag tttgtacttt
    25081 ataatttatt tctactaagt tattttcttt gaaaaatact tcatcagtat agttttctag
    25141 ttgaccaaac atagttttat ttttcatata atgaccatag actattaaac tcttatcatt
    25201 ttcaaaatta tttctataat ccatgaaaat actacctaaa ggaagataat ttttataaaa
    25261 atcatgagtt aggtagaaat cattgttata tccttgtact acaggatagt ttatatttac
    25321 gttgtttatt ttaagccaga atctataatc attattttta tcataaagtt cttgatgttt
    25381 gctattattg atagtgtttt ctctgagttc cgtatatact tcatcagctt ttttatattc
    25441 agataatttt atgtaaatcg aaaggctaga gaaagttagc gcaataatgc aaataatatt
    25501 tattaatatt tttactagtt tttcaattaa t
//
LOCUS       DAEPUT010000057        24682 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.059, whole genome shotgun sequence.
ACCESSION   DAEPUT010000057 DAEPUT010000000
VERSION     DAEPUT010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24682
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.059"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            90..2102
                     /locus_tag="KRL22_002521"
     CDS             90..2102
                     /locus_tag="KRL22_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1272994.1"
                     /translation="MRRNTKLLTTGILSMAIVAPAMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDTDSITLNYKCYDMPLDTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINGKNNPKTLNRQDLEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            2344..4257
                     /locus_tag="KRL22_002522"
     CDS             2344..4257
                     /locus_tag="KRL22_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1272995.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKITTYISFVKKELVKYWPLIIEKCDGISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     SKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKE
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDDIDEHSQYREILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFVEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            4250..6469
                     /locus_tag="KRL22_002523"
     CDS             4250..6469
                     /locus_tag="KRL22_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH1272996.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     KECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            6578..7408
                     /locus_tag="KRL22_002524"
     CDS             6578..7408
                     /locus_tag="KRL22_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBH1272997.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            7398..10865
                     /gene="addB"
                     /locus_tag="KRL22_002525"
     CDS             7398..10865
                     /gene="addB"
                     /locus_tag="KRL22_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HBH1272998.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKNTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGDNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDMNINPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            10865..14692
                     /gene="addA"
                     /locus_tag="KRL22_002526"
     CDS             10865..14692
                     /gene="addA"
                     /locus_tag="KRL22_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBH1272999.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKEDEIEEEEK
                     LDNIQLEARMVGKIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     MFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            14738..15949
                     /locus_tag="KRL22_002527"
     CDS             14738..15949
                     /locus_tag="KRL22_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBH1273000.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            15936..19463
                     /locus_tag="KRL22_002528"
     CDS             15936..19463
                     /locus_tag="KRL22_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1273001.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQTIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHNITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            19594..20847
                     /locus_tag="KRL22_002529"
     CDS             19594..20847
                     /locus_tag="KRL22_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH1273002.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            20996..22048
                     /gene="ytvI"
                     /locus_tag="KRL22_002530"
     CDS             20996..22048
                     /gene="ytvI"
                     /locus_tag="KRL22_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH1273003.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFRINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMESFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            22139..23365
                     /gene="pepT"
                     /locus_tag="KRL22_002531"
     CDS             22139..23365
                     /gene="pepT"
                     /locus_tag="KRL22_002531"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBH1273004.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            23572..24624
                     /locus_tag="KRL22_002532"
     CDS             23572..24624
                     /locus_tag="KRL22_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HBH1273005.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
BASE COUNT        10524 a         2370 c         4414 g         7374 t
ORIGIN      
        1 atattttggg ttagatacac tttgacatat tttcaaaagt taaaagatta aaaataaagt
       61 agaaatttat gttaagtaag gagattaata tgagaagaaa tacaaaatta ttaacaacag
      121 ggattctttc aatggcaatc gtcgcacctg caatggcatt tgctactgaa tctaatgcta
      181 tggaaaataa cgctgattta aatataaact tagagaaaaa aagtatcgtt ttaggtagca
      241 aatcaaaagt tagtgtcaaa tttaaagaaa aaccagatac agatagcatt acattaaatt
      301 ataaatgcta tgacatgcca ttggatacaa ctctaaatta caatcaatca actggggcat
      361 atgaaggaac tatcaattat aaccaagacc cagaatatct aaatgtttgg gaactacaag
      421 ggataacaat aaacggcaaa aataatccta aaactttaaa cagacaagac ctagaaaaga
      481 tgggattaaa tttaaaagac tataatgtaa cacaggaatg tataattgaa gacataactt
      541 ctagaaaaga tgtaaataaa tatttgagaa aaacttcttc acctattaca gaacttacag
      601 gaagtgatag atatgaaaca gcagttaaaa taagtaaaga gggctggaaa aatggttcag
      661 ataaagtagt tataataaat ggagatgtaa gtatagatgg cattatatca actccactgg
      721 caaccacata taatgcacca atacttttgg ttgaaaaaaa caatgtgcct aatagtgtaa
      781 aatcagaatt aaagcgccta aaccctaaag atataattat aattggagat gagaatgcta
      841 tttctaaaac tactgctaat caaattaaat caactgtaaa tgctagtcaa acacgtttaa
      901 atggttctaa tagatatgag acatctttat tgatagcaaa ggaaatagat aaaaatcatg
      961 atgtggaaaa agtatacata acaaatgcta atggcggaga agtggatgca cttactatag
     1021 cagcaaaagc aggtcaagac aagcaaccaa ttatattaac tgataaagat agtattacag
     1081 acaatacata taaatggtta aagagtgagg atttacaaaa tgcttatttt ataggtggtc
     1141 ctcaaatgat atcaacaaat gttataaata aggtaaatgg aataactaaa gatagtgtta
     1201 ctaataatag agtatacgga gcagatagac acgaaacaaa tgcaaacgta ataaaaaaat
     1261 tctatacaga tgatgagtta gaggctgttt tagtagctaa atcagatgta cttgttgatg
     1321 ctttagcagc aggtccattg gctgcgaact taaaatctcc aatacttata acaccaaaga
     1381 cgtatgtatc tgcataccat aaagataatt tagaagctaa atcagctaat aaggtataca
     1441 aaataggagg aggattgact tctaaggtaa tgagctctat agcatcatca ttatctaaac
     1501 acaatacgac tccaacagaa ccaggaaata gtgggggcaa gacagttatg attgacccag
     1561 ggcatggtgg ttcagcacct ggaaattcat ctggaggaat gattgaaaaa gattacaatt
     1621 taaatacttc acttgcaaca actgaatatt tacgttcaaa gggattcaat gtaataatga
     1681 caagagacac agataagact ttatctcttg gaaatagaac tgctctatct aattcattga
     1741 aaccagattt atttacaagt atacattata atggctcaac taataaacaa ggtcatggtg
     1801 tagaagtatt ttataagctt aaagataaaa atggagggac tactaaaact gtagctacca
     1861 atatattaaa tagaatttta gagaaattta aacttacaaa tagaggtata aaaacaagag
     1921 tacttcctag tgattctaca aaagattatt tatacgtttt aagaagtaat gatatgccag
     1981 ctgtacttgt agaatgtgca tttttggata atgaaaatga tatgagttta ataaactcat
     2041 ctgcaaaagt aaaagaaatg ggtacacaaa taggtaaagg aatagaagat tcattaaaat
     2101 aaatggaaat aaaaatattt aaaaacttaa tgtaaattta tagttgtaaa tttatactaa
     2161 agtcaaaaaa tgaaatataa gtgtatcaat agtaagactg tatgtacatt tgcacatgtg
     2221 aatgcaagta tatatacagt ctttttttgt agttaaatgc aataatttga ttgtgttttg
     2281 taaaatacac aatatgatat aattagataa tatacactta atttaattga ggaaggtgat
     2341 tatatggaat atttatttga aaaaagtagt ttaaaagaat atggaaatga agctttagat
     2401 aaatatagag aattattaga taaaactggt aataattcaa ggtgtattct tttgttagta
     2461 ccaaacaata acacaaagat acgatatgaa agggctctaa gattaaatta tagtgaagaa
     2521 ctgaaaataa caacatatat aagttttgtg aagaaagaat tagttaaata ctggccacta
     2581 ataatagaaa aatgtgatgg aataagtaca aaggttgtat ctccaacatt tatatcaaat
     2641 agtttaagtg aatatttaat agtgcaaaaa gttaaggaaa agaggataca agaaggatat
     2701 tttgaagata ttacaggaac caataaatcc atagcaaata gtataatgac taacataaat
     2761 aagtctgcat ttaatttaat tgattttgat tttattggag aaaaaatata ttcatcaaag
     2821 aaaaataaag atagtatata tagattttca tacactcaaa tggatgaaat tatatcatat
     2881 tatataaatt ccttactatc aaattcaatt ttagataatg cattaagcat atatttatac
     2941 aatcaatacc tacttaatga tgatttttat ttaaaaaact tatttacaga agtgagatat
     3001 ataattgtgg atagccttga aagctcaagt aatgcagaag ttgattttat aacagaagca
     3061 ttggataata cattacaaag ttatatatat tttgattata gtagggatta ttctgtattt
     3121 aataatgtgg atatagacta tataaatgag aaaataatat caaaaattaa gtctaaagaa
     3181 gaaaatatta aaaagaagga gattagaata gaagatttat acttattacc tgcaaatata
     3241 gaattaaatc aatcaagtca attatataat gaaatgttag atttaataag tgaaaaagtt
     3301 atatctctta tagaagaaga tgtatctcca agagatatag caattatatc tcctataaac
     3361 aatagtatat tggagcatca aattagagat tctttgatag aaaaaaatat agatgttttt
     3421 agtactaaga aggataaaaa agctgtggat tatccatatg ggaatgcatt ggtagtggct
     3481 acatgtatat tttatggata tttagatttt ataaaagagg atgaatactt aagcttttta
     3541 gaaactcttt tagaaataaa taggataaaa gcatttaaga tttttaatga aacaagacat
     3601 ttaagtattg atgatataga tgaacatagt cagtatcgtg agattttaca gtatattgaa
     3661 gaaaaaaaga agagtgatat aaaaatacat gaatttttaa ctcaatttta catagataaa
     3721 atgttaaatt taaaagaagg taaaaagaat gttgggttat gtaaaaagat aatagctgaa
     3781 agtgagtctt ttagtgaaag tttaagtcta cttgggatga aaaaagaaaa gatatttgta
     3841 gaagctttaa aaagtacaat aaacgattat tactctgttg tcgatataga agagttgaaa
     3901 tccaaagaca aaatagtaat aactactcct tattcatata tatcatcaaa tatagataga
     3961 agtatacaaa tatgggtaga tataggaagt aatgcttgga atatgaaaat agaaaaagat
     4021 ataagtaatt taattgtact tagaaaatct tttgaagaaa aaaagattta tacaaatgaa
     4081 atggaagaat attataaaaa atactatcta tacaatacag tatataattt gttattaaat
     4141 gcaaagaaaa tctatgcatt taaaagtgaa tatgcgatta atggttatat ccaagagagt
     4201 atattatata gtatactttt aaaaatctca cataaaggag ataaaaatta tgattaatat
     4261 aaattataga gaagaccaga taccaataat aaattacgat aatggtacta tggcagtacc
     4321 agcagtacca ggtgctggaa aaacatttat aataacaaat ttagtagcta aactattact
     4381 tgaacagaaa cataagggtg gtaaaatatt aattcttaca tatatgaata gtgctgtaaa
     4441 taattttaaa ggtagaataa gaaagattct tgaagagaat aaaatagatg atactaattc
     4501 atatgaagta atgactatac acagtttggc tgtaaaaata ataaaggaaa agccagaagt
     4561 tgtaatgtta agtgaggatt ttaacatagc tgacgatttg caaaaaagta ttatattaaa
     4621 tgaatgtata agtagattta gatttgaagg tggagaaaga gcttttagat ggtttttaaa
     4681 ggagcaaaaa gatgaacgct ggaaagaaat aactcttgaa gcctgggaaa gaggtttttt
     4741 tgaatttgca ggaaatgcaa taagtgaact taagtataag ggaatttctc cagataaact
     4801 tgaagaaata ttgtcaagag gacacaaagg aatgcttaaa attattttac caatatataa
     4861 attgtatgat agaaaattaa agcaaaatgg attgctagat tatgatgata tattaatttt
     4921 agcagaaaaa actttaagct tagacgaagg gcttagaaag aagtttcaaa ctagatacaa
     4981 atatatattt gaagatgagt gtcaggactc aaatgaaatt caaggtaata taataaaaat
     5041 tatatctagc gaaaataaaa acctagttag agttggagat ataaatcaga gtataacagg
     5101 aacattttca tcatcagacc ctaaattttt taaagaattt ataaatagtg cagatttctg
     5161 ttataggatg gatatgtcaa atcgaagttc aaaagatata cttgatttag caaacactct
     5221 tgtcaagtat gttacaaagg aatttagaca gaaagaatgt agacatgctc ttgaagatat
     5281 gcaaataaaa actgtgccaa atggaatggg atataaagaa aaccctaatc cagaacatta
     5341 taatataaat gtaaagtggt atgagagttg gaaaattgaa atagagcaaa ctgctagata
     5401 cgttaagggt ataaaaaata aatatccaga taaaagtata ggtatattgg ttccatttaa
     5461 tgaacaagtg acacaagttg ctaaagaact tagagagaat aatctaacct ttgaagaatt
     5521 aggaccaaat tctttgaata aaaggaaggt tataaacaac atagcatata ttattgattt
     5581 tatgttgcat tgtgatgatg tagaaaagtt aatagttgta cttaataaag tttttataga
     5641 tactgataat gaagaagaaa taaagtattt tttagaagaa ttaaaaaact attctaccga
     5701 agaaattatt tataattttg aatttagtaa gttagataat gatttaatag aatttaaaga
     5761 agaaagtgat atatacttaa gttttaaaag aggaatagat attataaaac agatattaga
     5821 atatccaata ataaggttag acctcttagt tttgtttatt gggaaaaaac ttaatttaga
     5881 aaaagaagat aaagctgtac tggattatat atctttttat ataaagtatc tagtatcaga
     5941 aaatataaat atggatttag aagatgtata taatttattg tttgatgtaa agaacagggt
     6001 gtttaatcat ataatagatg tggtatatga gataaatgga tatgaaccag agcccggtag
     6061 tataacacta tgtaactatc ataagtcaaa ggggatggaa tgggattgtg tgtttttact
     6121 aggtcttgtt gaatataatt tccctgacaa tattaatcaa aagtttcaga gtgataaatg
     6181 gtatctaaaa gaaaaatata aaaaccctat ggcaattatt aaatcagaag ttgaagctat
     6241 attaaaagga agtatttcaa cagattatgc tcataaaacg aagattgatt ctataaatga
     6301 aaagattaga cttttatatg tagggattac tagagcaaag gaaatgttag tactttcagg
     6361 aagtgcttat agagatgaaa gtgatatagg gaataagaga aaagagcaaa aaccatgtat
     6421 atatttaagc agacttaatc aacatattat tgaaaaaagg tcaaattaat atataataag
     6481 ttattaaaag attgcttgaa atatatctaa aaggggataa aacaatatgt acagtaagta
     6541 actactaaaa aataaagtta agagagaagt gatatgagtg aacgataaat taaaatattt
     6601 ttcttatagt caaaattcaa ttaacacata taaatcatgt ccattgaaat ttaaatataa
     6661 atatattgat agaataaatt ggaaaaatga tgatgttggt agtagagagt attatgaaac
     6721 tttaaaaaca ggaagagatt ttcatttgat ttgtgaaaga tattttagca atatacctct
     6781 tggaatctat tttaatgagg atgataaaaa tagtaaaaag tttttaaagt ggatggaaaa
     6841 tataaaaaaa gttgttccta ttgaaaaagg aaaaacgtat ttgccagaat atgaagtaag
     6901 gatgacatta aatggggata taatacaggc aaagtatgat ttagttgtaa ttggaaataa
     6961 caatatagaa atatgggatt ggaaaaccga gtctaaaaag attgactata aacacgtaga
     7021 aaatagaata caaactattg tttatatgtt tttagcaaaa gaagtaatac ctaaagtttt
     7081 aaaaatggac ataaatgtta aagatataaa tatgagatat tatcaacctg aatttgatga
     7141 cttaccaatt accattttat atgatgaaga aaaacatgaa gcaaatagaa ataaaattca
     7201 aaattatata agtatgataa aaaacactaa ttatgaagaa catacatacg aagacaatct
     7261 atacaatgat atagaaaagg tatataataa agaagaacgt atgtgctata gaaataaaaa
     7321 gcattgcaag tattgtgaat ttaataagtt atgtaatggc aaagaaatag attatagtat
     7381 tttggaggcg gaaatttatg ggacttaggt ttgtattagg tagaagtgga agtggaaaat
     7441 ccacctatat actagatgag attaaaaaag aagctcaaaa aaatgaaacg acatcaatta
     7501 tacttttagt tccagaacag tacacatttg aggctgaaaa tagagtaagt aagctattct
     7561 taggaaaaga aaaagataag tatctaagag ttagggtact tagctttaag acactaagta
     7621 atatagtttt ttctcaagta ggaggattga cagatgtaaa tataaattct agtggaaaag
     7681 caatgatggt atatagagct attgaagatg taagtgaaga attaaatgtg ttttcaaaat
     7741 caaaatcgca gtctggtttt gtaagctcaa ttacagatat gatatcagaa atgaaacaat
     7801 acaatataag ccctgaaatg ttagaaaata tatctggaga attggataat gaaactttaa
     7861 gtttaaaatt aaaagatata agtaaaatat ataattcttt tgaagggaaa ttgcatgaaa
     7921 attatgtaga tgctcaagat atgttaactt cattggcaag taaaattgaa ttaagcagtt
     7981 atttagatgg agcttgtgtt tatatagatg aatttacagg ttttacacca aatcagtaca
     8041 atgtcataaa gagtatatta aataagtcta aaagtgttaa tatctctttg actgtagatg
     8101 atatcaacta tattgggtac agtaaatctg atatgttttc tagaacgaaa tttacttatt
     8161 caaaattgac tcaattgtgc aacgaagaag gcataaaaat attgccacaa gtaaatttaa
     8221 acacaggtgt tataaaaaga tttgaaaaag ttaaggaatt acagcactta gaaagatttt
     8281 ataatgctta tccatataaa atatattcaa atccaactga aaatataaag ataaaagagt
     8341 ttaacaattt atattcagag gtggaagaga tagccagaga aattgtacat ttagttagag
     8401 ataagaatgt aagatataga gatataacca ttgctacaag agatttaaat agatatgatt
     8461 ttttagtaca ctctatattt aatgaatata atataccaaa ctttatagat aagaagagag
     8521 aggcaaaaag taatccaata gttattttaa ttatttcagc tttagaaatg aagaatagac
     8581 gatatgggta tgaaactatg tttaggtatt taaaaagtgg acttatagga attgataatg
     8641 atgatataaa tttactagaa aattatgtgt tggctaatgg gattaaaggt aaaaaatggt
     8701 ttgatgaaaa atgggattat agaataaccc aaagtctttc aggtcaagaa agtgaatttg
     8761 aactggaatt aaaagagaaa ataaatgaaa taaaaaatag agtattagag cctatagtaa
     8821 ttttacaaga aaaattaaga ggaaaaaata gagtaaaaga aatctgtaga tatatatatg
     8881 aatttttatt agatataaat atgccagaaa ctatagaaag tttaatagta aattttaagg
     8941 ataaagggga acttgatgtt gcaaatcaat actcacaagt ttgggacata gtagtggaca
     9001 tattagacca aatggtggaa cttatgggtg atgaaataat ttctttagaa aaatttataa
     9061 aattaataac cttaggtttt gatgaatatg aattagggct ggttcctcct agtatagacc
     9121 aggtacttgt aagtagtgtg gatagaatga aaaatccaga cacgaaatat ttatacctag
     9181 ttggaactac tgatggtgtg tttccgctga ttacaaagga tagtggaata ttgagtgata
     9241 atgataggga aagtcttgga aacaaaggaa tcgaagttga tattgatagt aagactagga
     9301 gttttgaaga acagtttctt gtatataaag ctcttacttc gacatctaag aatttaacca
     9361 taacatatcc aatatcagac catgaaggta aaacgcttag accatcaata attatatcaa
     9421 gacttaagaa gatatttcca aatatagaaa ataaaagtta tttagtggaa gaaaataaaa
     9481 acactgataa agatatactt aaaaaaataa cggttaaatc ccctacattt aatgaactta
     9541 taaacgtaat aaaaaattat gacagtgatg gttacaatac agaagagatt aatagtattt
     9601 ggttagatat atataggtac tatttaaaag atgaaatcta tagttctata acaaaaaaag
     9661 ttataaaagg tcttagttat actaatcaag ttcataagat tgaagagaaa aaaataaggt
     9721 cattgtataa aagtaattct cttagcatat ctaggcttga aaaatatgct gaatgtccat
     9781 ttgcttattt tatacaatat ggtctaaaag caaaaaagcg taaagagtat tcatttacac
     9841 caccagattt aggaactttt attcataata ttttagatag gttttcaaaa gaacttttac
     9901 aagataattt aacttggaga gatattgatg aaaaatatat agaattaaag ataggtataa
     9961 tagttgatga aataatttta aagataccag gatatatatt aaatagttct gagaggtata
    10021 aataccttgc atatagatta aagaatatgt tgacaactgc tataactata attagtcagc
    10081 aaataaaaca aggttcattt gaaccaatag attatgaagt taaatttggc gacaatggaa
    10141 aatatccacc tataaaaatg gtgttagaaa atggacaaga agtaagttta attggacaaa
    10201 tagatagagt tgatgaattt gaagaaggag aaaataaata tataagaata atagattata
    10261 agtcaggcaa taagtccata agtctaacag aaatatatta tggtctacaa ttacaattac
    10321 ttgtgtattt agatgcaatc cttgaaagtg caaaggatga agatatgaat ataaatccag
    10381 ctgcaatact atattgtaga ataaataatc caatagcaaa atttaatgaa gataaagatg
    10441 atgaagaaat acaagaagca atattaaaag aacttagaat gaaggggctt gtagtaaaag
    10501 actctcacat agttaaagag atggataaat cattaataga tggagaaagg aaaaactctt
    10561 tagtaatacc agtaggtctt actaaggatg gaaatgtagg taaaagtact tcagcaataa
    10621 gctatgagga tttcaaactg cttagaaaat atgtaaggca tgctataaag gatttatgtg
    10681 aagaaatgtt aagtggagaa atacgtatag ctccatataa acataaagat ggaacatcat
    10741 gtgacttttg tgattactct gctatatgtc agtttgattc aactataaaa gataacaagt
    10801 ataaaaattt aaataataag agtaatgaag agataataaa aatgatgaaa ggagatgtta
    10861 attagtgagt tctcctaaat ggacaaaaga gcaattagaa gttatagaaa gtagagaatg
    10921 caatttattg gttgctgctg ctgctggttc aggaaaaaca gccgttctag ttgagcgtat
    10981 aattcaaatg ataacaagta gagaaaatcc aattgatata gataagttat tagttgttac
    11041 atttactaat gctgctgcgt cagaaatgag agagaggata ggggatgcta taggaaaagc
    11101 cttagatgaa aacccagaaa ataaacattt acaaaaccaa cttgttttat taaataaatc
    11161 tagtattaca acaatacact cattctgttt ggatgttata aaatcaaact ttcatagaat
    11221 aaacttagac cctaatttca gaataggaga ccaaactgaa tgtgctattt tgaaacaaga
    11281 agcaatagag gaagtatttg aagatttata tgaagaaaga gatgaggggt ttttaaattt
    11341 agttgaaagt tatgcagaaa gaggaggaga taaagaagta caagatatta tcttgggaat
    11401 atattcattt gcaatggctt ctcctgaacc taaaaaatgg ttgattgact cagcagaacg
    11461 atttaatatt gatgaaaatt ttgatttttc acagtctatt tgggctagag ctatattaga
    11521 cactgtaaaa atagagatta atggtctttg tctaaatatg gaaagggcat taaaagaagt
    11581 ggaatcaata gaagaattag aaacttttgc agaaaagtta tccgttgaat ataaaaaaat
    11641 tgctgacatt tcacaagcat gtaataaatc ttgggatgag gcatataaaa agatggcaag
    11701 tatgtccttt gaaaattatg taaaaggagt aaaaagaatt tcaaaagatg ctccttcgta
    11761 tataaaagaa tcaaaagaaa aggcaaaaac tataagagat aagactaaga agtctttaga
    11821 aagtatagta agtgctacat tcaataaaga taatgattct attagagaag aaataaaata
    11881 tctttataac atagttaaac caatatctag tgttgtactg agatttgaag aggaatatag
    11941 caataagaaa agagaaaaag gaataataga ttttaacgat atagagcatt ttgcattaaa
    12001 tatacttaca gatgtagatg aaaaaggtaa tattgtacct tctgatatag cagttggata
    12061 tagaaacaag ttttatgaaa tatttataga tgaatatcag gatagtaatc tagtgcagga
    12121 agtactgctt aaagctgttg caaatacaga aactccaaat agatttatgg ttggtgatgt
    12181 aaaacagagt atatatagat ttagacaagc aaagccagaa ttatttttgc aaaaatataa
    12241 taactataat gataaaaagg gaagctccca tagaaaaata atgctttaca aaaactttag
    12301 aagtagagaa gaagttgtag atgctgtaaa ttatatattt gaaaatataa tgaatgagaa
    12361 tataggagaa attgaatata cagaaaaaga aagactaaat ttaggtgcaa attttaatgt
    12421 ggatacagac gagaaatcta ttattggtgg agcaacggag atacacctaa tacaaaaaga
    12481 taataaactt gatgatgata ttataaatga taaagacgat agaattaata acaaagaaga
    12541 tgaaatagag gaagaagaaa aattagataa tatacaactt gaggctagaa tggttggaaa
    12601 gattatcaaa gatttaatga aagtcaatga agatggaaaa attcaaaagg tctatgataa
    12661 gggaatagat ggatatagac ctgtggaatt tagagatata gttattcttt taagagctac
    12721 atctgcatgg gctccagtgt ttgcagatga attgatgaat atggatatac caacatatgc
    12781 tgatgttgga gtggggtatt ttgatacgat tgaaataaaa acaatattgt cattacttca
    12841 aataatagat aatccaatgc aagatatacc tcttatatct gtattaaaat cacctatatt
    12901 tggatttaca ccagaggatt tgattgatat tagagttcag agtaaagata aaatttttta
    12961 tgaggtttta aaaagtacag cagagtatga tggatttaca gattctcaaa atgaaaatga
    13021 gtctgagttt ataccaagtg aagagtgcat aaacaaaagt aaagattttt taattaagct
    13081 aaaggaattt aaagaaaagt caatgtacat gagtacagat gaatttatat ggtacttgta
    13141 cacaaggact ggatactatg cctatgttgg agcattgcca ggtggaagtc aaagacaagc
    13201 taatttaaaa gtattgtttg agagagcaaa acaatttgaa gaaaccagtc ttaaaggaat
    13261 gttcaacttt gtaaatttta tagagaaatt aaaaaaatct agttctgata tgggaagtgc
    13321 aaaaacactt ggtgagaatg caaatgttgt tagaataatg agtattcata aaagtaaagg
    13381 tctagaattt ccagtagtca tatgctctgc aatgggtaaa aatttcaata ctcaagattt
    13441 taaaaagagt attttatatc atcataattt agggtatgga cctcaatttg tagactatga
    13501 gagaaggatt tcttttccaa gtatagccaa agaagcatta aaaagcaaaa taaatataga
    13561 aaatttatca gaagagatga gagttttata tgttgcattt acaagagcta aagaaaaatt
    13621 gattataact ggttctacta gaaatataca agatagtata aagagatggt caaatggaat
    13681 tgaaagttta gatacaatat cacaatacga gatattaaaa ggtaaaaatt ttttagattg
    13741 gataatgcct tgtgtattaa gacataggga tttatctaat ctactagaag aagtaggatt
    13801 agacgcagtt tttaatgttg aacataattc aaaatggtat ggaaagttgt ggaataagaa
    13861 tgatatttta gtggaaaaga agagtgatga agaaaaagaa agtattgaag aaattcttga
    13921 aaaaatagat gtagataatc ctgacagtga ttattacagt gaaatagaag aaaaattaaa
    13981 ctatatatat ccatatgaat ttagtacaag aaaacctgct actatatctg ttacagaaat
    14041 aaaaaagata caaaataatt atgaagaaga gttaataaat actatatttg aacaaaaagt
    14101 aatattaaaa aagcctctat ttattcaaaa tgaagaagaa agagaaaaaa taagtggaac
    14161 agaaagaggt acaatagtcc atttagttat ggaggtttta gacttaaaaa atgtaagtag
    14221 tgtaaatgat ataaaatcac aaataagagg ttttgtttca aaaggtataa taacagaaaa
    14281 acaagctagt atagtaaatc catataaaat atataaattt tttgcctcta acataggaaa
    14341 aagaatgttg aatgctgaaa ttataaatag agaaaaatcc atttatgcac aagtaaatat
    14401 gaaagacata tatatttatg aaaagcttat aaacaatgat gataaaaaac tttatgataa
    14461 tgaaagtgtc atgttaagag gtatagttga tgcttatttt gaagaagata atcaaatagt
    14521 tttggtggat tataaaacag attttgtaaa tgaggaaaat ataaatcaaa taatagagaa
    14581 atataaaaaa cagttggatt tatatgcaga tattattgaa actttaactg gtaagtcagt
    14641 aaaagagaaa tgtatatatt tatttggagt tgatgaagct gtttgttatt agtttttata
    14701 tataaattaa acctaaaaga tagaggaagg ggaaaaaatg agatttattc atacatcaga
    14761 ttggcatcta gggaagtccc tagaaggcca ttctagaatt gaggaacaag caaagttttg
    14821 tgaggaattt ataaaaatag tagaatcaaa tgaaatagat atggttataa ttgctggaga
    14881 tgtatatgat acttctaatc ccccagcaca agcagaaaaa ctattttatc agactgtatc
    14941 aagacttgcc aataatggtc agaggtgtgt attaataatt tcaggaaatc atgataatcc
    15001 agagagactc tctgcaataa cacctctagc acatgaacag gggatactta tatatggtta
    15061 tccattaagt gctacgatag aagctaagta taaagggttt gaaataacat atgcaactca
    15121 gggatgtaca aaactgaata taaatggaga aaatattgtg gttgctacat taccttatcc
    15181 aagtgaaaaa agattaaatg aagttttttc aagtgaagat gagtttgaga aacaaaaaaa
    15241 ttattctgaa aaggtaggag atatatttag aagtttagaa gaaaatttta gaagtgatac
    15301 tataaatata gccgtatcac atatatttgt aataggtgga gagagtactg aatcagaaag
    15361 acctatacaa ttaggtggaa gttttttagt tgaaagaaaa gatttgccag aaaaggctca
    15421 atatactgca ctaggtcatt tacataaaca acaaaaagct tccgaacgtt taaatgcata
    15481 ctattctggt tctccacttc aatatagcaa ggatgaaaga gcgtatacca aaggggcata
    15541 catagtggat ataaaagctg gtgaaaaacc aataattgaa gatgtatatt ttaataatta
    15601 caaacctata gaagtattta aatgtaatgg aatagaagaa gcactagata tatgtgagca
    15661 aaatcaagat agagagattt ggtcatattt tgaaataaat actgatgaga taatatcaca
    15721 gaatgaaatt aaaaaaatga aggaactatt aaaagacata atagaaataa aaccaataat
    15781 aacatcttgt tatgaacaag aaagtgtaga tataaaagaa aagtctatgg cagagttgtt
    15841 tagagagttc tattctttta gtaaaggtgt agagccaaaa ggagaactta tggatttatt
    15901 tctagatata ataagtgaag aaggtgaatc agcagatgag accaattaga ttagaactta
    15961 cagggcttaa tagctatatt gataaacaag ttatagactt tgaaaaatta attgaaagag
    16021 gtttgtttgg gatatttgga actactggaa gtggaaaatc tacaatctta gatgcaataa
    16081 ctattgctat gtatggaaat atatccagaa atacaaaaga atatataaac agtgtgtgcg
    16141 ataaggcaat tatatcatac gagtttgaga taggaagcaa aaacactaga agaagataca
    16201 ttgtagatag aaccattgct agaagcaaaa caggaacaaa gacctctaat gctagattaa
    16261 tagaagtatt gaatgacaat acccaaaatg ttttagctga taaagttgtg gaagtaaatg
    16321 aaaaagtagc acaggttgta ggattaacag caaatgattt tactaggtca gtagttttac
    16381 cacaagacaa atttaatgag tttctaagat tatcacgtgc agatagaaga gacatgttag
    16441 agagaatttt taatcttgag aaatatggaa gaagtcttgg agaaaaagtg aaaaagagaa
    16501 aaaatataca gttacaaaat ttaaaagatt tgaaatcaaa attaagtcaa tatgatggaa
    16561 ttacagagga agtatataac aatataaacc aagaattaat agagttaaaa aatttggaaa
    16621 aagataagaa taatgcttta gacctagctc aaaaatctta tgaagaaagt aaaacagtat
    16681 atgaagaaca attaaaatta gaaaaaaatg aacttagaaa aaatgagctt gatttaaaaa
    16741 atagtgagat aaaagaaaag attgctcttg tagaaaatga tagtaacgct aaaaaggtag
    16801 acccatacat aagttcagtt caaaatctag aaaaaaagat agatgaagat agctttgcag
    16861 taagtaattt agaaaagaaa ttagcaatat taaatcagga gcttgaagtt acaaaaaata
    16921 gatatgaaaa aataaacaaa attaagaatg aagaagtccc taaattgagt gaagaaaaaa
    16981 taagattgca acaaacaata aaattagaag aagagttagt tttattagat agagagttaa
    17041 aagagctaaa agaaagtgga attaatttaa ataaaactaa agttgaatta gaaaaagtaa
    17101 agcaggtgtc agagtccaga aaagatgcag ttactaaatc tataaaagaa gttgaaggaa
    17161 agattgataa agtaaatata agtgcagaat taaaacaaaa aatatttcta gcatatgaat
    17221 acgagaaaga ttacaacaac gtattggaag aaaaaaatca aaagctaaat aaactagaag
    17281 aaatactcaa agagacagaa aatataaatt taaaagttag atatattgat aaagataaga
    17341 atgatgtaaa tcgtaattta gaaaatttat cacttcactt ggatgttctt cttaaaaaat
    17401 gtcctggtaa gagtgctgat ttacttttaa aatctgaata tgttactgaa ttaagaaata
    17461 aagcaaataa tactaaagaa aatgaaatta agaaaagcag tatacaagat gaattaaaga
    17521 taatacttga aagtaagttt aatactgaaa gggaagtaaa tttactaaat gaaaaacttg
    17581 aaaataatag aaagaacaga gatgacctag aaaaagaatt agaagaacta aagtatttaa
    17641 atttagcctc tgaacttaga cgtgaattaa aagaaaatat gccttgtcca gtttgtgggt
    17701 caaaacatca tgaaaatcat aatataacta aatatgatga aaatatatct tttgtcaaag
    17761 aaaaactgga gaaattagaa aaagaaaaaa taagtataag aaacaatata gaggaattaa
    17821 atgctaaagt aagtgggtat ttatctatag aaaaaatgaa gactaaagaa cttgaagatg
    17881 taaaaggaaa actagggggg attccatcta gtcaattatt aaaaaaactt gatgaagaac
    17941 aaagaaaact tgcattgtta aaatctaata ttcaggagtg ggagaaagaa aaagagagta
    18001 ctgaaaataa agtaacatta gctaaagaag aaaaaaataa aattgaaaaa gaagaattaa
    18061 aaataagaga gagtctgaat aattataaga aattaacaag agatttaaac atagaaatag
    18121 aaggtttaga aaataaatgt aaaaaactta aacaggaata cctaggatta aagacgatta
    18181 ctaaagtctc taatctattg tcaaaagtaa aagaaataag ggagaatgaa aaagaattag
    18241 aattactaag tactgggcat tcaaatttat taaaaaatag agactcacta gatattaaaa
    18301 taagagaaaa tgagagtaaa ctacatgaaa tagagataga attaataaag gctagagaat
    18361 tatatgtaga aaagaaattg agtagagata ataagtataa agaagttatt agcataacga
    18421 aaggtgattt agctaaaaat cttttacata atgttgaaga aaatatatgt aagatattag
    18481 aacaagaaga atcaagtaag aaaaaattgg aagagcaaag attagaatat gaaaaaaaca
    18541 ttgctgaaaa gcacaatata gatggtagac ttaaaactgc taaggaacaa tataaagacc
    18601 aaaaatcaac actaaataaa ctattggcag aaaataaatt tgaaagtata tatgcagtaa
    18661 aaagagcttt attagatact gatgcagtaa aaaaattgat tgaagaaata ctagagcatg
    18721 aagaagaaca aaagttatta tcatttaaaa taaaatcatc aaaagaaaaa ttaaatggaa
    18781 gaagcataaa gaaggagtac tttgaacagt taaaagatga aatttataat ttgaaagtag
    18841 aaataggaaa tatatccaaa gatattggag ctaatcaaaa tcagttaata acattaaaag
    18901 actctttaga taagataaat gattttaata aacaacttaa ggtagttgaa cacaatgtgg
    18961 acttattgga agaattagat aaatgtgtac aaggaaataa atttgtagaa tatgtttcta
    19021 caaaccaatt aaaatatata gcgttggaag catcaaaacg attggatgga ataacaaaag
    19081 gaagatatgc acttgaaatt gactcaacac taaactttgt aatgagagat aactttaatg
    19141 gaggagaaag aagaagcatt gatactctat ctggtggaga gacattcttg acatctctat
    19201 cattagcact tgctctttca tctcaaatac aattaaaggg aagtgcacca ttagaatttt
    19261 tctttttaga tgaaggtttt ggttcattag atagtgaact tttagaaatt gttatagaat
    19321 ccttggaaag attgcatagt aataatctaa gtgtgggtat aataagtcat gtcgaggaac
    19381 ttaaaaatag agttcctgtt aagctattag tttcatctag tgaggctgga ataggttcaa
    19441 aagtaaaaat tgaatatagt tagaaaatat atgttaattg aatatattat ctaatatttc
    19501 caaataatat gtaattgtga tataataaaa actaatatta aagttattta taattaatat
    19561 taatataaaa acatgtaagt aggagtgtgg taagtgttgg aatcgcccaa taatttgatt
    19621 cagattattt ttttaatagt attacttata gggtctgcat ttttctcagc atctgaaacg
    19681 gccttaatgt cgttgagtaa aatcagaatc agatatatgc aagatgaagg agttaaagga
    19741 gctaagttag taagttcatt aatagaaaat ccaaataagc ttttaagttc tatattggtt
    19801 ggaaataacg tcgtaaatat agcagcaaca tccatatcaa catctttgtt tataggatta
    19861 atgggagaaa aaggagtggc acttgctaca gctgttatga cagtattagt attaatattt
    19921 ggtgagatta ctccaaaaac aatagcagca aataattcag aaaaggtttc tctattggta
    19981 tctaaaccta taaaagcaat tatatttata ttaagaccaa tagtatggat atttaatata
    20041 attacaaata ttatatttaa attatttggt ataacaaata aaggagctaa atcattcata
    20101 actgaagaag agctaaaaac tatggtaaat gtaagtcatg aagaaggcgt ccttgaaatg
    20161 gaagagagag aaatcataaa taatgttttt gaatttggag atatgcaagc taaaaatgca
    20221 atggtacaaa gaatagatat ggtagctata gatatggaag atagttatga tgagataata
    20281 caggtattta aaactgaaaa attaagtaga atgcctgtgt atgaagaaac tatagatgat
    20341 attgtaggaa tacttaatat aaaagatatt atatttttat ctgatgaaga aatagagtca
    20401 tttgatatta aaaattatat gagagaacct tttttcacgt atgagttcaa aaagataaca
    20461 caacttcttg aagagatgaa acttgaaaaa agtcagatgg ctatagttgt agatgagtat
    20521 ggtggaacat ctggactttt aactatagaa gatttagtag aagtcattgt tggagatata
    20581 gaggatgaat atgatgaaga agaggatgaa atacaagtta taaaagaaga tgagtatatt
    20641 gtagatggaa gtactaaaat tggtgatgtt aatgaactta ttggtgtaaa cttggaatct
    20701 gaggagtttg attccatagg aggttttata attggacacc taagcagatt gccagaagaa
    20761 aatgaagtaa ttgaagttga taatataaga ttttgtatag aaagtataga aaaaaataga
    20821 attaaaaaaa taagaatata tacataatgt aataatgttc ttaaatttat tagaagtgta
    20881 taaatataaa agatatcttt tatatttata cacttctttt tattttgtat tcaaataaaa
    20941 ctagtatgaa atggacaaaa taaaaatata aattagaaga aaggagattt ttaagatgag
    21001 catactagaa aataattttt tatacaaatt aaaaaacaac actatctttt tttgtatata
    21061 tacattgtta tttattttta tttacaaagc gtttccatac atagctccat tttttctagg
    21121 tgctataata gcacttatga ttaatcctat atcacaaaag ttagaaaata agtttcgtat
    21181 aaataaaggt atctctactc ttgttctaag ttttcttgca gtggctatag tcagtacagt
    21241 tactacaata atagtaataa attcaatgaa agaattaatg ggatttttaa ataatatatc
    21301 tgctaatcct gaggatataa gtaatactat tatgtatttt ttaaataaaa taaatgactt
    21361 tatggaatca tttcaagaaa tagccaattt tgatgtagaa caattagtaa acaaattcag
    21421 tggtgaagta atgcaaatta caaaaaatct tcttactagt atacttggat tggctacttc
    21481 tattccatat attataatat ttataattac cttgtttatt gctacgtact ttatagcaaa
    21541 agaccttgat aagattgaaa atagttttta taatatgttt actgttgatg ttagaaagaa
    21601 ggtaaaaaac gtaaagaaag aggcagggct ttcacttgtt ggatatataa gagcctatac
    21661 aatacttatg gctataacat tttttgcaat ctggggaagt tttgctttat ttggattgaa
    21721 atatggtcta atagtagggt ttgtaggagc tttaatggat ttaattccat tcctaggtat
    21781 aataacaata tatcttccag taattgttta ttatttcctt ataaaaaatt attttatagc
    21841 tataagtatg actgtgatat tttttgtttt gtctttgatt agagaaatac ttgaacctaa
    21901 actagtatca gtaaatgttg gactaaatcc attagctacc ctagcagcga tttttattgg
    21961 aatccaagta aaaggaataa ttggagtaat tttttgtttg ggtttggtat gtatgcatga
    22021 tatacttaag aaggtggata ttttttaatt ataataattg atagattttt ttaaaaataa
    22081 aattttattc acaggtaaat aaaaaaatat taatcttatt aagaaagagg gtatatacgt
    22141 gaaacaaaaa gtagtggaaa gatttttaaa atatgtatca tttgatacaa catctaattc
    22201 tcagtgtgag aactgtccat cttcagaagg tcaaagagtt ttagctaagt atatagttga
    22261 agagctaaaa acaatgggtg ttgatgatgt gagtttagat gaaaatagtt atataatggc
    22321 tactttaaaa ggaaatactg atggtgtgga tactatagga ttcatatcac atttagatac
    22381 aattgaagat gttagtggaa aagatattaa accaagaata atagaaaatt atgatggaaa
    22441 agacatagtt ttaaatgaag cgttaaatgt tattacgtat gtaaaggatt ctccagagtt
    22501 ggaagaattt aaaggtgacg atttaatagt cactgatgga acaactctac ttgggtctga
    22561 tgataaagct ggtatagctg agatagtgac tgcaatagag tatctaataa atcatccaga
    22621 aattaagcat ggagatataa aaataggatt tacaccagat gaagaaattg gtagaggtgc
    22681 tgatttattt gatgttgaaa aatttggagc aaaatatgca tatactttag atggaggaat
    22741 agttggagaa cttgaatgtg aaaattttaa tgctgcaaat gcaaccatta ctatacatgg
    22801 tagaaatgtt catccaggtt cagctaaaaa taaaatggta aatgctatac atatagctgc
    22861 tgaaatatca gaaatgttcc cagcagatga aagaccagaa acaacagaag gatatgaagg
    22921 attttggcat ttaaattcta taggtggaaa tgtcgagaat gtaagtatgg cttatattat
    22981 tagagaccat tgtaaagaaa aatttgaaaa tagaaaatct attatgatag agaatataga
    23041 aaaaataaat aagaaatacg ataatagagt ggaattggat ttaaaagact cttattacaa
    23101 tatgaaagaa aagattgagc cagttatgtt tatagttgat atagctaaag aagctatgga
    23161 ggaattaggt ataaaaccac gtttagttcc tgtaagaggt ggtactgatg gagcaagatt
    23221 atcttttaat ggattacctt gtccaaatat atttactggt ggattaaact tccatgggaa
    23281 aaatgagtgt ataccagtta gttctatgga gaaagctact aaactaattg taagaatagc
    23341 tgaaaaatat gctgaaagag tttagttaaa aagtatttaa aaattaagca tttaaagtta
    23401 taatagctat atcattcttt ataagtcaag ctgattataa gcttgtgttg tacttaaaat
    23461 ggtatagcta tttttgtaat tatttttata aaagataatt atttttagtt tagggtatca
    23521 ataaaaagta tgaatatcaa taggtattaa catttaaaag ggggaattgt attgaaaatt
    23581 aaatctaaaa aaataatagc atttgcactt tcacttggga ttatgttgcc aagttgtgta
    23641 tatgcagaca ctattagtaa aaatcaaaat gcacaggtag atatgaacaa ttatcttcaa
    23701 ggtagaaaat ctccaaagga ggaaaaactt attggtgaag atagatttga tacagcgata
    23761 aaaatatctc aaagtggttg gaataatggt tcagaaaggg tgtttctagt taactcaaat
    23821 tcattgccag atgcattggc ttcaactcct ttggcaagta aattggatgc accaatactg
    23881 cttacaaata aaaatagtat accatataat gtaacagagg aaataaaaag gcttaatcca
    23941 gcagaagtta ttttaattgg aagtgaagga gctatttcat caagtgtaaa agaatctctt
    24001 gaagatatgg aagtattagt cagtagaatc ggtggagcag atagagaaga aacatcttta
    24061 cttcttacta gacagctaga tgatactggt gatttaggtg tctcaaaagt ggcagtggtt
    24121 aatgggtata atggactggc agatgcaact tcaatatcaa gcccagctgc aagtgataat
    24181 acagctataa tatatacagg taaggatagc ataagaagtg aggcaaagaa ttttattaca
    24241 caaaactcaa ctaagacata catagtaggt ggggagtaca gtataagtaa aaaacttgaa
    24301 ggacagttag taaactcaga aagactagca gggacagata gaaaagatac taatgcgaaa
    24361 gttttagaaa agttttatgg aaaatcaagt aaggttaata atatgtattt tgcaaaagat
    24421 ggaagtggta gagaagctga tttagttgat gggcttgctg ctggagtatt agcatcaaaa
    24481 acaaagtcac ctgtagtact tgcaagtgga agtttaagta gtgcacagaa aagttttata
    24541 aaaaaagtaa aggctgataa atttgtacaa gttggtggag gtaaaaatag taaaccatat
    24601 gcagaagcat tagccttaca gtaatattgt gtaaatcaaa attaatatat aataatagca
    24661 agtaaaccaa gttgcacttt aa
//
LOCUS       DAEPUT010000058        24672 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.060, whole genome shotgun sequence.
ACCESSION   DAEPUT010000058 DAEPUT010000000
VERSION     DAEPUT010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24672
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.060"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            154..474
                     /locus_tag="KRL22_002533"
     CDS             154..474
                     /locus_tag="KRL22_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HBH1273006.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            612..1256
                     /gene="trmB"
                     /locus_tag="KRL22_002534"
     CDS             612..1256
                     /gene="trmB"
                     /locus_tag="KRL22_002534"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBH1273007.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            1385..2131
                     /locus_tag="KRL22_002535"
     CDS             1385..2131
                     /locus_tag="KRL22_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273008.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(2260..2538)
                     /locus_tag="KRL22_002536"
     CDS             complement(2260..2538)
                     /locus_tag="KRL22_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273009.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            2813..3259
                     /locus_tag="KRL22_002537"
     CDS             2813..3259
                     /locus_tag="KRL22_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273010.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYNNVLIAKLKYILCKNKENDTNLKESEV"
     gene            3529..3981
                     /gene="accB"
                     /locus_tag="KRL22_002538"
     CDS             3529..3981
                     /gene="accB"
                     /locus_tag="KRL22_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBH1273011.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            3997..5358
                     /gene="accC"
                     /locus_tag="KRL22_002539"
     CDS             3997..5358
                     /gene="accC"
                     /locus_tag="KRL22_002539"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBH1273012.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            5373..6227
                     /locus_tag="KRL22_002540"
     CDS             5373..6227
                     /locus_tag="KRL22_002540"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBH1273013.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVITGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            6248..7192
                     /locus_tag="KRL22_002541"
     CDS             6248..7192
                     /locus_tag="KRL22_002541"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HBH1273014.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            7381..7641
                     /locus_tag="KRL22_002542"
     CDS             7381..7641
                     /locus_tag="KRL22_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HBH1273015.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            7794..8165
                     /locus_tag="KRL22_002543"
     CDS             7794..8165
                     /locus_tag="KRL22_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH1273016.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            8195..9040
                     /locus_tag="KRL22_002544"
     CDS             8195..9040
                     /locus_tag="KRL22_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273017.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            9361..10488
                     /locus_tag="KRL22_002545"
     CDS             9361..10488
                     /locus_tag="KRL22_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1273018.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            10592..11227
                     /gene="lexA"
                     /locus_tag="KRL22_002546"
     CDS             10592..11227
                     /gene="lexA"
                     /locus_tag="KRL22_002546"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBH1273019.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(11374..12531)
                     /locus_tag="KRL22_002547"
     CDS             complement(11374..12531)
                     /locus_tag="KRL22_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1273020.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(12859..13491)
                     /locus_tag="KRL22_002548"
     CDS             complement(12859..13491)
                     /locus_tag="KRL22_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH1273021.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            complement(13484..14842)
                     /locus_tag="KRL22_002549"
     CDS             complement(13484..14842)
                     /locus_tag="KRL22_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273022.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            15012..15764
                     /locus_tag="KRL22_002550"
     CDS             15012..15764
                     /locus_tag="KRL22_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011098710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273023.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEAISISDKVAILSKRPATIKNIYDIELN
                     MDGTKTPLKTRKVPDFQKYFDILWKELDTHEA"
     gene            15754..16554
                     /locus_tag="KRL22_002551"
     CDS             15754..16554
                     /locus_tag="KRL22_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273024.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(16988..17524)
                     /locus_tag="KRL22_002552"
     CDS             complement(16988..17524)
                     /locus_tag="KRL22_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBH1273025.1"
                     /translation="MQGGVNIRQVKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVVIGILHN
                     REISMKEYIYFCYRQFKK"
     gene            complement(17929..18438)
                     /locus_tag="KRL22_002553"
     CDS             complement(17929..18438)
                     /locus_tag="KRL22_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273026.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGRLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            19260..19697
                     /locus_tag="KRL22_002554"
     CDS             19260..19697
                     /locus_tag="KRL22_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBH1273027.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            19836..20624
                     /locus_tag="KRL22_002555"
     CDS             19836..20624
                     /locus_tag="KRL22_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1273028.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            20669..21127
                     /locus_tag="KRL22_002556"
     CDS             20669..21127
                     /locus_tag="KRL22_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273029.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(21229..21579)
                     /locus_tag="KRL22_002557"
     CDS             complement(21229..21579)
                     /locus_tag="KRL22_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273030.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(21581..21964)
                     /locus_tag="KRL22_002558"
     CDS             complement(21581..21964)
                     /locus_tag="KRL22_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1273031.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            complement(22469..22852)
                     /locus_tag="KRL22_002559"
     CDS             complement(22469..22852)
                     /locus_tag="KRL22_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273032.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
     gene            23201..23692
                     /locus_tag="KRL22_002560"
     CDS             23201..23692
                     /locus_tag="KRL22_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH1273033.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            complement(23835..24569)
                     /locus_tag="KRL22_002561"
     CDS             complement(23835..24569)
                     /locus_tag="KRL22_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1273034.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
BASE COUNT         9141 a         3098 c         3610 g         8823 t
ORIGIN      
        1 taaagtaata aaatattata taaaatattt taaagcctta ggtaatatta ggtagaagtt
       61 ttagtaaaat atgcaaaaac taattgatta tgtaccttgt atgggtatat aatagatatt
      121 gttttaataa aatatttgaa agggaatgat ttgatgaaaa ttactttacc agaaacagct
      181 attgatactt taaaaagtat cttaaaagac aatcaagata aacctaataa tataagagta
      241 tactttgcag gtgttggttg tggaggtcct tcttttggat tagctttaga tgagaaaaaa
      301 gaagatgact taacttatga agttggagaa ttacaatttg taatgagctc tgatgaatat
      361 agtcagtatg gagatataat aatagaagat acaggatttg gatttagagt tattcctgaa
      421 aatatgaaag atcaaggtgg aggaggatgc tctggttgtt cagggtgcca ctaagattaa
      481 gtttttagta agtttagaac tctctttata gaaataaatt tctattttaa gagagttctt
      541 tttatttttt ggtgagataa tgtataataa aaatgtattt tactaatttt ttatatgtaa
      601 ggagaattat tgtgagaaga agacgaaaaa aaggtgcaga tgaaaagctt ttaagttata
      661 caaaatatgt tttaagagac gatatagaca aattaaaagg caagtggaat ttaaagttta
      721 gaaatgataa tccaatacat gttgaatttg ggactggaaa aggtaagttt ataacaactt
      781 tagctaagca gaaccctgac ataaattata ttgccatgga acttaaggaa gaagttcttt
      841 taaaggctgt tgaaaaagca gatgcttcta atttgaataa tatactattt ttatggggag
      901 atgtaagcaa tattttggat tactttgaag ctaaagaatt atcgagaatt tatataaatt
      961 tctgtgaccc atggcctaaa aatagatgga gtaaaagaag actcactcat tctggatttt
     1021 tagaaatgta caatagggtt ttggaagatg atggcgaaat tcactttaaa acagataatg
     1081 aaaaattatt cgagtttagt ttaaatgaaa ttgctgcaaa taattggcta ttaaagaata
     1141 tttctcttga tttaggaaat agtgagtatg aaaataatgt tacaacagag tatgaagaca
     1201 aatttatgtc acaaggtatg cgaatattta gatgtgaagc taaaaaacgt aactagtaat
     1261 atgtttataa gtttaatagt agaaatttat tttaatttat attaataaag tgtacgaaag
     1321 taggtatata taacaaggaa acagaaccct ctcatagaaa ttaaattatt ataataaaaa
     1381 atttatgtgg gagggtacta tgaatttagc taatttaata ccatttatta tttctgcagc
     1441 agctttaagt ccaataaatt caaatgataa ggttttgagc gaaaatcaac ttaaagatat
     1501 ttttcctgat gcaaatttaa gagcagttgt aaaaagatat ataaatccag atgagatgac
     1561 tataagcaat ataaaggctt tagatggaga attttatgca actggtgaga gcatttcaaa
     1621 tttaaaaggt atatcatatc ttgaaaatgt agacaatttt attttttgga ataataatat
     1681 aaaagaggtt cctaaggaag ctttaagtct aaaagatatg gattcaataa atcttgccaa
     1741 taattatttg attgatgatg atgtagtaaa ttctctttct cataatggtg tggatgtaaa
     1801 ttgcgattta aattttattg atacaaaaga taatcagtat aaactggact ctaaatatca
     1861 taatgttgat atagcaaaag gtgaaagtat tgatttgaga aaaataatta cgaagaaaat
     1921 tgatagttat tataaatact gggaagttac tgataacctt ccaaaagatt taaattttat
     1981 tgtatctgta agtgataaga gtgtactttc atgtgaagat atgataatta aaggtaataa
     2041 aacaggtcaa gcagtggtaa aagttatact aagcgacaaa aatgatttaa atacatctca
     2101 agaagttcta attactgtca atgtaaaata atctgtcaac ttattcaatc attctatttt
     2161 caatttaagt gtataatcaa aataaaggtt gttagtaaca gaacgctaat attagtgctt
     2221 tgttactagc aacctttaaa ttttatagaa atagattatc taaaaaattc catttcttct
     2281 gttagtagcc catattccta ttaaaattat cagtgaatat attatataca aaactattct
     2341 tatatattgg acatctaatc caaaaaattc aatgttactc tgtgaggtat gcaacatcac
     2401 aaggactgca gatataccaa taagcaaagg attgattact atttgcttat cagttcttaa
     2461 aatcattatt ttacccatcc aaattattga taatataaaa aataaaattt taagaccaaa
     2521 ttctaatgta tctaccaaag cgaaaacatc ccttcattta taataaattt ttcagctcaa
     2581 caaaatataa aaccctacaa acaacttttg aatccataat aagataactt gattaagcac
     2641 tatgaaataa gtactataaa acttcatcta cattaatata tactacacta tacttcaaat
     2701 ttcttaaaca taaattaatg aaattaacaa aattttattc agaaacatat aaagatatat
     2761 tttactattt aaatgcatat cattatatat acagttttag gaggtgaggt atatggaatc
     2821 taaatttttt aattggtaca ctcaatcctt agggggaact tttggcatta tatcatgtat
     2881 atgcgcatat ttaaatggat acatgtttgt ttatacaaat agtgctagca aatattttga
     2941 aagtatagga tttctgggaa taatttcaag ttatacacta cttccacttt gtatgcttac
     3001 tttgattttt ggagttatat attcttatac tccagaaaca tctgacaaaa gtattttcaa
     3061 tatacctttt tttactttaa ataaaagatt aatacttatt acagtagttt ttggttttat
     3121 aggtgctaga gtttacttta taattcctgc aattctaata acttttaacc tatataacaa
     3181 tgttttgata gctaaattaa agtacatcct atgtaaaaat aaagaaaatg atactaattt
     3241 gaaagaaagc gaagtctaaa ttgcataata ttggtatttg tcttaaaaat tcccgaggta
     3301 ttaatttgta ttctcttgta ttttgcaaaa aatattgaat tttattcatt ttatacttat
     3361 aatttatatt aataatggaa aattaaaaca aatataagtt actggttgtt aatttaaaat
     3421 taaaagatat attgatgtgt tgattctcta gtcagcactt tttcttttat aaatttgttt
     3481 tttgtgatat aatattagca ccaggtaata atacaagggg gtaacaaaat gaacatcaat
     3541 gaaattaagg aattattaaa ggccatagac tcaactaact tagaatatgt aaaacttgaa
     3601 agtagcgatt taagattaga agtatctaaa aaagctcaat ctacaagttc acctgtttta
     3661 agtgtacaac aagaatcagt agtggatctt tctttagaaa agccagttgt aaacgataca
     3721 cctgtcacat ctaatgagaa tctatcagta gtagtagctc ctttgatggg aacattctat
     3781 gattctccaa gtccagatgc agatagcttt gttaaagttg gcgatgtagt tgaagaaggc
     3841 gacactttat gtatattaga agcaatgaag cttatgaatg agataacaag tgaaattaaa
     3901 ggtgaaataa ttgaagtatt agttagtaat gaagaactag tagaatataa tcaaccttta
     3961 tttaagataa aaccattgta gtaggaggta tttaagttga taaaaaaaat actagttgca
     4021 aatagaggcg atatagcagt tagaatcatc agaacatgta aagaactagg tataaaaact
     4081 gttgctatct attctgaaat agataaagat tgttttcata gatatatagc tgatgaatct
     4141 atttgtatag gaccaaataa tataagtaag agttataata atatagaaaa tataatctat
     4201 cttgctctta aattaaagtg tgatgctatt catccaggct ttggattttt atcagagaat
     4261 cctgaatttg caaagcaatg tgaagataat aatattattt ttataggtcc aacaagagaa
     4321 caaatgattt tgatgggaga taaatctaga gcaagagaaa ctatgatgga attgaatatc
     4381 cctgttgttc ctggttcaga atctgttttg aaaactaagg aagaagcttt agaagttgca
     4441 agagaaattg gatatcctgt tatgataaaa gcctcaagtg gaggcggtgg aaaaggtatg
     4501 agaatcgtta gaaaagaaga agaacttttt tcaaattttg atatggcaag ttcagaagct
     4561 ctagcagcat tttctaatag tgatttatat atggaaaagt ttatagaaaa tcctagacat
     4621 atagaagtac aagtatttgg agataaacat tcaaatgcaa tacatttagg tgatagagat
     4681 tgttctatgc aaaggcgaaa tcaaaaagta atagaagaat ctttaagtcc atacctttca
     4741 gatgaagaaa gacaaaaact tcataaaatt gcagtagata tagtaaaagg agtaggttat
     4801 atcggtgcag gtactattga gtttatagtt gacaaagata aaaactttta ttttatagag
     4861 atgaatacaa gaatacaagt tgaacatcca gttacagaga tggtaacaaa tcttgacctt
     4921 ataaaacttc aaatatctat agctaatggg gataaaattc cttttaaaca agaagatatt
     4981 acttttagag gtcatgctat tgaatgtaga ataaatgcag aagattcatc aaagaatttt
     5041 gctccatcac caggtaagat agaatcatta aatttacctg gaggttttgg tgttagattt
     5101 gatacttttg tatatgcagg atatactata ccacctttat atgattctat gataggtaag
     5161 ttaatatgtt gggctgaaac tagagaagaa tgtataagta gaatatatag agctctagac
     5221 gaaattattg tagaaggtat taatacaaat gtagaatttc aaaaggcact tgtaacaagt
     5281 gaggagttta gagaagatac tcatcatacc aaatttatag aagatgtctt tatgaagaaa
     5341 gaatttgcta cattataagg agtaaataga ttatgataaa aaaattttta tcatcaaaag
     5401 aatctaagta tgttacgatt tctttagatg acaactttaa aaagaatagt gtagatgata
     5461 aattttggac ctattgcaaa ggttgtgata gtcatgtatt tagaaaggac atagaagaaa
     5521 attcatttgt atgtccaaaa tgttcaagac attatggctt aagagcaaga aaaagaataa
     5581 atttattgat tgataaagga acttttatgg agtttaattc tgatgtagaa tttcaaaatc
     5641 cactaaattt tcctaaatac aaagaaaaag tagattctta taaggaaaaa acaaaagagt
     5701 cagaagctgt tatcacaggt tatggaagaa taaatggaat taaaacagtt atttgtgtaa
     5761 tgaatcctga ttttatgatg ggaagtatgg gttctattgt tggggaaaaa ataacttatt
     5821 caatagagta tgctgctgaa aataatttac ctataattat ttgttctgct tcaggaggag
     5881 ctagaatgca agaaggtatg gtatctctta tgcagatggc aaagacttct caagcacttt
     5941 ctaagcttga agaaaaatca ttgccatata tatcagttct aactgaccct actactggag
     6001 gagtaactgc tagttttgct atgcttggtg atattataat ttctgagcca aatacattga
     6061 taggttttgc aggtccaaga gtaatagagc aaacaataaa tcaaaaactt cctgaaggat
     6121 ttcaaacttc tgagttttta cttgaaaaag gttttattga catgatagta gatagaagaa
     6181 aaatgaagga agtattatat caaattcttg ctatgcacaa gaaatagggc ataaaggagg
     6241 aactgttttg attgaaaata atagtgaaaa aataaaagtc ttagaaaatg atattaaaca
     6301 attaataact atttctaagg caaataatat agatttaagt gataaaataa attcacttaa
     6361 tgagaaattg gaaaagctta aggaagatgc tttttcacat ctatcagcat atgaaaaggt
     6421 aacactaagt agagatataa agagacctac gacattggaa tacatagaac atatttgttc
     6481 taatttttta gaacttcatg gagataggct ttttaaagat gacccttcta tggttggagg
     6541 aattggtcag ataggaaagt ttaatgttac tatagttgga caccaaaaag gaagagatac
     6601 aaaagaaaat ataaaaagaa attttggaat gcctcatcca gaaggataca gaaaagcatt
     6661 aagacttatg aaacaagctg aaaaatttaa tagacctata ataacgttta ttgatacatc
     6721 aggagctttt tgtggtctag aagcagaaga aagaggacaa ggagaagcta ttgcaagaaa
     6781 cttacttgaa atgagtaaac tttctgttcc agtaatcact tttgtaattg gtgaaggtgg
     6841 tagtggagga gctttaggta tcggagtagg aaatgatgtt tgtatgttag aacattcagt
     6901 ttattctgta atttctccag aagggctttc tagtattcta tttaaagatt catctaaagc
     6961 taaagaagct tgtgatgtta tgaagcttac aagtaatgat ttatatgatt taaaaataat
     7021 agataagatt ataaaagaac ctcttggagg agcacaaaaa gatgtagaag ctgtttcaaa
     7081 agaaataaaa gcttatattt tagaaagatt aaatcattac aaagatatgg ataaagagga
     7141 aattatagct caaagatata aaaaatttag aaatattgga aaatgcttat agaatataaa
     7201 gaaatttgta gttttttcat aataaaatgg ttaaaaaaaa taaaggtttt cttaaaacga
     7261 ttatagaagt atatttttat aaaagtatac tttaaatgat gattgtaatt agtaaatggc
     7321 aattatgatt tagtacttta ggtaatggat actttaacaa attaacaagg agatgttgaa
     7381 atggaggtac taaaagtttc atcaaaatct aatcctaatt ctgtagctgg agccttggct
     7441 ggagtactaa gagaacgagg cgttgcagaa atacaagcta taggagctgg agctctaaat
     7501 caagcgataa aatcaattgc aatagcaaga ggttttgttg cacctagtgg aatggattta
     7561 gtttgcattc ccgcatttac tgatatagaa atcgaaggtg ataagaaaac agccattaaa
     7621 cttataattg aacctagata atatatctct ttattagaat ttaattaagt tttaaaggtt
     7681 ggctatagaa ataggacact atagtgaacc ttttttactt tatatgtttt attttatgta
     7741 acttttaatg tataatctta agtaaacaaa taagattgga ggaaatatac attatgaaat
     7801 taaaattatt ggtagaagag tatgcagtat gtagattaaa taatgacagt aaaataccaa
     7861 catggataga tacagagaag ttttattcta taactagaac tgatgatgaa ttaagtgttg
     7921 tatgtttaaa taataatatt ccttctgatg ttaagtcaga aaaggagtgg agaatactta
     7981 agatactagg tcctttagac ttttcacttg taggaatttt atctaagtta agtagtttgt
     8041 tagcagacaa caaaataagc atatttgcaa tttctactta tgatacagac tatatcttag
     8101 taaaagaaaa agatatagaa aatgcttgta aaattttaag ctgtaatgga tatgaagtag
     8161 agtagttaaa tacttttaca tgaggactta acttatgatt tatataatcg aaattttaaa
     8221 aataagtgta ataaatattt tttgtttcat aggaatattt attgtatttg gattgatttt
     8281 tagcattaca gaaaatctaa ataataaatt tatattttca tcttttggaa aaactggaat
     8341 cattgtaact ggagctatag gaacgtttgt tcatgaattg agtcatttga taatgtgttt
     8401 aattttcatg cataaaataa attcagttaa gtttttcaga ccaatagaaa gtaaaaatga
     8461 tggtatacta ggatatgtaa gtcatagcta taaaaaagat aatctttatc aaagtatagg
     8521 aaatttcttt ataggaattg cacctattat aggtggaaca ataatgatta ttttaatttt
     8581 taagatatta ctgccagata gttatatgaa agtgactcaa aatatagatt taaagttata
     8641 tgtaagtatg attaataatt taaatataaa tgggtttata cacattattt taggtgatat
     8701 ttccaatttt ataagaataa tgttgttaac acctagtgta tattcattga agtattttat
     8761 atttatgttt ttaatgtatt ctatatctac acatatgtca cttagtagtg ctgatttaaa
     8821 aaatagctta aatggtctga gctttatagt tatagttatt tttgtaataa gttcaattac
     8881 atacttattt ggatttgata acttgaatat atccagttta atagttaagt ataacatatt
     8941 tataagtttt tttatggcaa tagggtttat tttttcaata gtaactctca taatatccta
     9001 tattttaagc ttagtcagcc catttaaaaa ctttagttaa ataaatacat attttactaa
     9061 tatttggttt cgttagaaac atataaaaat attatataaa aaagatttta gtagagcata
     9121 aaaaatttct caatatattt taaaatattt ctataaatat attgagaaat aaaaaagagt
     9181 acttaaattc aactagtttt taaatgtgga tttagggaat agttagtgat aatttcatct
     9241 aaagcactgc taatctctta aaaatgtaaa aaatgattaa attaaatatt tatactcact
     9301 tggtataaat atcaaaaaat aatataaaag atttatattt tagttttagg aggtttaatt
     9361 ttgaataatg ataagaaaat tataaaagta cataataaat cagataaacc tgataatatt
     9421 gttatcaaag aaaatgaact catagaaaaa tgtctacttt tggaaaataa acttcctgta
     9481 tttatgaagg attattttat atatttaaaa ggttctgttg cagtttctac acgacttgct
     9541 tatttagaag atattaattt tttttgttca tatttgattg aaaccaaaga attaacaaat
     9601 gcagattgtg taaaagacat tacagaagat gattttaata caataaaatc aagagatata
     9661 aatttattct taggtgatta ttgcagtaga tattacaaaa atacagaaaa aaacacattg
     9721 atttttgaaa ataacaatag agctttagca agaaaaaaat catccatctc tactctattt
     9781 aaattcttat acagaaactc tcagatagat aataatataa ctgatggatt caatccaata
     9841 aaacttccta aacctcagcc agatgctatt aagcgccttg agatagatga agttgctaag
     9901 atgcttgaat cagtagaaac aggtgaaggg cttacagaga aagaaaaggt atattggaga
     9961 aaaactaaat tacgtgacaa agctatacta gcattatttg ttacatacgg gcttagatta
    10021 aatgagctta gagaactcaa tatctcctct tttaattttt caagaggtga atttaaaata
    10081 tatagaaaac gtgggaaaga agttttaatg cctataaatc atacttgtga acatgtaata
    10141 aaagattatt tgcaaaacga aagaacaaga gatgaactat taaatgatga agaaaaagat
    10201 gctttatttt tgtctcttca aaataagaga attacagcaa aggctataag aacactggta
    10261 aaaaaatata catctattcc acttgatact actagagaca atggatatag tccccataaa
    10321 ttaagagcaa cggctgcaac ttctctaatc caaacaggat tttctatata tgatgttcaa
    10381 aacttacttg accatgataa tgtcacaact actcagcttt atgcagctca taagaaaaat
    10441 gtaaaacgtg atatagtcaa gaattttgaa tggattgagg acgattaaaa atcaggaaca
    10501 aatgtttgca gatataaatg gattatgtta taattaaaaa tataaagtgt atggaaataa
    10561 aaacaaaata tgtttggaaa tgagtgatgt tatgtattta gatctaactg aaaagcaagt
    10621 cttgatattg gaatttataa agtctcaaat catattaaaa ggttatccac ctgctgtaag
    10681 agaaatatgt actgctgtag ggttaagatc tacttcaact gtgcactctc atctaaataa
    10741 acttgaaaaa ctgggataca taagaaagga ccctactaaa ccaagagcta ttgaagtttt
    10801 agaacgtagt aaagtaaatg atgtttctgg agctaatcaa gaaataatag agcttccttt
    10861 agtaggtcaa ataacagctg gagaacccat tttagctcaa caaaacatag aggaatacat
    10921 tccattccct gccagtttag taaagggcag taacaatttt gtattaagag taaaaggcga
    10981 aagtatgatt aatgcaggaa ttttagatga agattacgtt gtagtagaca aaaaaaatac
    11041 agccttaaat tctcagatag tagttgcact tataaatggt gaatctgcta cagttaagag
    11101 gttttttaaa gaaggaaatt taataagact tcagccagaa aatgatttta tggaaccaat
    11161 tatgctcaat gactcagaag ttgaaattgt aggtattgta actggtgtat ttagagttat
    11221 taaatagcta ttaaaaaata cttaaaaaaa taagctattc gtatagataa aatgtgttat
    11281 ctattgatta tagcttattt ttttatgcat ttattttatt ttttaaatga tttaaagttc
    11341 agaagcttta tagataaatt ggttgttttt ttgttatttt ccataacata tatcacatgg
    11401 gtcatttttc ttactttctg caattgtgcc tgataatatt tttttacttc ttgaaagccc
    11461 actacaattt tttgtagagt gataactctt accttttgga gtaaaataca ctatttcttc
    11521 tgaattggat gtattttgtt tatttttaaa agaatcattt ttacttgtat tactgtttga
    11581 ttttccagag tttccatctt ctctaacgcc tttattataa cttccatctt tacaacttgt
    11641 aaatactcca tcacctgttg attcaaatat tatatctgaa cactcatcac ttctatgtac
    11701 ttttactccc atttttttta atttattcat tgtctcctga tgtggatgac catatgaatt
    11761 acccttgcct actaaaagaa ccgcatattc aggatttact ttatctaaaa actcttgaga
    11821 tgaactacta cgagaaccat gatgagctac ttttaaaagg tctactttct caagcttagg
    11881 tagtatttct ttttcggtac cttcttcagc atcacctgta aataaaactt tatcattccc
    11941 attagtatat acaaggacta gagattgttc attagtagta tctcccccat ttgtatttag
    12001 aacttcaaaa taagaatctt ctaaatagaa cttattattt tcaagcggta cacttgggga
    12061 taaaccctta tttgctaaag catttataaa gtccctataa ctctttgttt ctgctgaacc
    12121 attcgataca aaaacatttt ctatattaaa gtttttgaca acagaatcaa gtccacctaa
    12181 atggtctgca tgagaatggg tagctataag atatttaata tcttttacac cttgattgtt
    12241 taagtaatct accattaatc cctcatcatc attatctccc ccatctatca atgtaaaagt
    12301 tttaccatct tgaatcaata ttgcatcact atttccagtg tcaataaaat gaatttttac
    12361 attcttatca cttgatatac tactagacaa agaatcatta ttatttgatt gattatttcc
    12421 attatctgat gtagtacaac cagttaaata aatcgatata gatactatca ataaaagtat
    12481 caaagtttta attttagaat tttttttatt ttttatactt atttctatca caaactacgc
    12541 ctccatattc ataatactct agtaattata acatgatatg cgtttttatg atattttttt
    12601 acataatatt ttaaataata gattatagta caataatata gaaaattgat actgtataat
    12661 ttttatatta tataaaatga aatattttac atcagtagta tccagttatg cattttaaac
    12721 gaccatttac gtttaatata ttgcaaactg cttctaaaaa ctataatatg ttaagtatca
    12781 acaaaaataa ataaactttt tccttaaaga aggcttaaag ctcacaccaa ctgccttctt
    12841 ttttttataa aaatttaatt atttattttg attaatattt atttcgtatt ttagttctac
    12901 tcttctagat gcatctctat tcacgctatt gtcaccattt ttgatgagtt cagcttttga
    12961 ccttcctatt gcaataatat gcttagtcac tttatctttg tatttatagt cacctatttc
    13021 atctcccact ataaatttag caacgctata tgctcttctt tgcgataaat ctaagttgta
    13081 tatataactt cccacatcat ctgtatgacc ttctataact attttggata tatagtcacc
    13141 ataatcttta taaatagtct ctatgtactt tggaacaaac atttttagca tttctttagc
    13201 ctctggtttt aaaacatcac tatctacatc aaacatggtt ttttcaccaa aagttacttg
    13261 cccattagat ttatctacct tcacaggtat tccacttttt ttaaaagttt cttcaacaga
    13321 agcattgaca ttcttagcta aatcttgttc aacagaacct gaaatacttt ctgagctaaa
    13381 taagataaga atcacaacca tcaatacagt agataataaa tctgtaaatg ttggccaaaa
    13441 gctactcttt tcaaattctc tgttaacagt tcttctatat ttattattca tttaactcat
    13501 cctcacctat gacctttatt tctttatcct ctatctcata aatttcttca ctgaaaggat
    13561 taaatacatt attaacatca tccttaaata attcttcact atcaagagga acttcatcat
    13621 tcataaaaga gttattaaac ataacatcta acttatcttg aatatctaaa gaattttcaa
    13681 acatcatatc cagtttaact tgtaggtcat tagaaaagtt ttcaataata cttgagagat
    13741 tttttattga gtcatctaag gtaaactttt catctaaaag gattttttga ttttgagata
    13801 ttttattttc gtgggtcatt aatttagtta ataaatcttg agcacttctt tcatatagag
    13861 caaatcctgc atttatattt tttatataat ctctaatttt gaattggctt tcagtggcat
    13921 tgtatatatt ttttgaagat tcttttatat caaataaaat ctctttattt atattatctt
    13981 gattatcata tttatcaaaa agctttacaa attttatatt taaaatatta aactgtttat
    14041 ctaattttct tacgctctgg tcaaatgtct taatagaact ttgagaacct tctaaaaggc
    14101 tttttaaagc ttctatacca ctgataaatt catcattaaa gtcatttaaa tctttagata
    14161 ttttatcaaa tttttcaata gcttctatag acttacttat ttgttttatt gtatttttta
    14221 cctcttctac ttttaaatcc attctttctg acttaaaatg agttatttca gatgttagta
    14281 aattttcaga ttttaacatt atttgtatca aaacatgttc acaatctttt atcttagtaa
    14341 agtaacctat aattagagaa aatacaactc caaatatact agttgtaaat gcagtttgca
    14401 tactactaat agttgaagga agtgaattta taatgtcttt agtatcaaca cataaaagca
    14461 ttgtagaaag accaacaaac gtacctaaaa ccccaagtaa tatacttatt gaagatgaat
    14521 tttttatact tctaattttt tctaacaatg gcaaattatt atgctttaaa tcagatacaa
    14581 cttcctctat aaatgaagtt atatttacgt ctgcataagg attttcttta ctatatgtat
    14641 agtagtcatc ccttaccttt ttataaaact cacttgtctt ataatctcta ttgatttcgt
    14701 ctaattttga acttacaaat gaatatactc tgttattttc tattatttta aaaacagaat
    14761 acacagttat tgcaagtaaa aacaatatag ttattggatt agtaaatatt gactctatta
    14821 aattcgttat tatgttactc aaatttatcc cctaccttat aatttattta tctataattt
    14881 atacgtacaa gttactaaga aaatacgtaa ataaacaaaa tatttatatt atatttatga
    14941 aaaatggtac aaataggtca tattgttaat aacataatat atacgagcta aaagttatag
    15001 ggggtggcat aatgaatgac aacatagtag aagttaaaaa tataaatatg aacttctaca
    15061 ctaaggaagg cgagcttgaa gtattaaagg atgtcaattt taacttgaaa gaaggagaaa
    15121 tattaacttt gcttggtcct tctggaagtg gtaaatctac aatattaaat attcttacta
    15181 atcttttaaa accgactagt ggtgatataa agattactgg aaatattgga tatatgtttc
    15241 aaaaagataa tttgcttgaa tggagaaata taatggataa tataactatt ggattggaaa
    15301 ttcaaggcaa aaaagataaa aaatctttag atagagttga aagcctttta aagacttatg
    15361 gattatggga ttttagaagt atgtatccaa aagaattatc tggaggtatg agacaaagag
    15421 ttgcgcttat tagaacactt tctgtaaatc cagatattct acttttagat gaaccttttt
    15481 cagctcttga ttatcagact agattattag tttgtgatga tgtttatagt attattaaga
    15541 atgagaataa gtctactatt ttggttacac atgatattgg tgaagcaata agcatatcag
    15601 ataaggttgc aatactatct aaaagaccag ctaccataaa aaatatttac gatattgaac
    15661 ttaacatgga tggaacaaaa acgcctctca aaacacgtaa agttcctgat tttcaaaagt
    15721 atttcgacat attatggaag gagctagata cacatgaggc ttaataaaag atctgaagga
    15781 tatataaact atgttaaagg tgtaaaaaga gaaaaaagaa atgtattatt ctaccagcta
    15841 ttaattttaa ttggttttat tgtaatctgg gaacttttag ctgacttaaa tgttataaat
    15901 acatttctat ttagcaaacc aagtgatatt tacaatttat ttattcaata tgcatttagt
    15961 ggtcaattat ttaaacatat tggaatatct gtatatgaaa ctgttcttgg tcttgttata
    16021 ggtactgtat taggtatttt ggtagcaatt gctctttggt ggtcagaaaa attatcaaaa
    16081 atattagacc catttttggt agttttaaat gctcttccta agactgcttt agctcctata
    16141 attatagttt gggtaggtgc tggaatagaa ggaatcgtcg taacagctgt aacgatttct
    16201 gttgttgtta ctatactttc agcttataat tattttatga atatagatga agaaaaaatt
    16261 aagatgttaa aaagctttgg ggctactaaa tctcaaatat tatttaaact catattacct
    16321 gcaaacacag gaaatttaat aaatttaact aaaattaata ttggtatggc atgggtaggt
    16381 gtaatagttg gagaattttt agtttcaaga tatggaatag gctacttgat agtatatggt
    16441 tctcaagtat ttaaattaga tttagtaatg atgggagtat ttgtattggc tatctgtgct
    16501 tgggcaatgt acgctgtagt taatattata gaaaaaatat acaattccag ataaataaaa
    16561 attttattta gaatatttga tgtatcagtg attataataa aaaatgattt ctttacagta
    16621 atcatttttt taaattaaaa taaagcgtaa gtttttgatt atcttcttat aactcatcat
    16681 gttgctagca cagctctatt ttatgggctt tgctggcttt ttattgcctc caattatata
    16741 cataatgctt aaatacagtc atttctttat tacctatgct taaatttcta caaaagaaaa
    16801 gacagtcaat tttttaatca aaattaactg tgctttatat ttaattttta atttttattt
    16861 ttgtgctccg tttgttagat atcagagact taattagtgc tcacagttta gcccaaaagc
    16921 ttaagtaagc caactatttg ctgtgattaa ataagtttac cttgaaactt aaatttatct
    16981 tctaaattta ttttttaaac tgacgatagc aaaaatatat gtattctttc attgatattt
    17041 ctctattatg caaaattcct atgacaacaa atattatttc tgcaacagta aggtagcagt
    17101 cttttaagtc gaaaataaaa aagcttggta tctgcaaaaa atctaaactt cctccccaaa
    17161 ataatttatc tatcaagcta catattgtac cagcaagtcc acaagacata attactttta
    17221 ctgaatagct tgtttgttca ttttttgatt tataaaaagc atatccagat ataataacta
    17281 atataactaa aatgttaaac aataccaata cccataaatt agatagaata ccaataaagt
    17341 ttcccccata agagagattt gtattttgaa caggattgaa tcttaaaaat ttcccaatta
    17401 tatcaatttc aaagtccatt aagaataatc ctataagaac tttgctaatt tggtctaaga
    17461 atattaagga tataactgga aaaacaaaag actttacttg cctgatatta acacctcctt
    17521 gcaaaagtca ttcacttttt ccttactcag tattgttaaa tccaaaaaag gaatttcgat
    17581 ttattaattt cacatcaata attataacat gagtaaatta tcaagtcatt tcttttctga
    17641 tttcgtagat aatacttatc tccatatatt tctactcgta gtcgttgtac aaatcgttgt
    17701 aaatcatgct accagacctc gcatttcctg catcttacgc atgagagtat aagtccagca
    17761 gtcttgcttc ctgtacttta cttaatgcgg ttttgggcct actgtcgtcc tcaataactt
    17821 cgcttagttg gaaatccaaa aggttcttcc ttacatagtc gtcctcgatt gccatgtaga
    17881 atgacgcttt taaggaacgc ttgctgtatt ataaaaagca gagttacttc atattttctt
    17941 acgtgtcaaa aagattccaa taattgctcc tataaggaca atcggtacta atctgacaaa
    18001 tagccactca aaagcatgaa aagctactcc aaaaacagcg gtttcagggt cggtataatt
    18061 ccaatccaag taaggactat ttagtctccc taagaccaca aaaactatta atatgactgc
    18121 acataataaa ataaataacc aatgaaacat ttttcttctc atgttttttc tttgtgcaag
    18181 ttgcaagttt ataatctcta atttttcaga aatcactttt aagttatcaa cttccgactc
    18241 aacaatagtt tctccaagta aagtgcttac gggcgtttca agcacctctg atatggaaat
    18301 caacatatca gaatcgggaa ccgacagtcc ttgttcccat ttagatattg tttgtcgcac
    18361 tacattcagt tttatagcaa gttcttgttg tgaaagtcct tttgacttcc tgattgtttt
    18421 aatgttttcg cttaacatta gggctaacca cctttctttc agttgttacc gatattatag
    18481 gcaaaactgc ccattgcttc aagcaacgca ttttaacatt caagtaaatt tcttcttttt
    18541 cctttaaccg ttttgcttat atacagtttt tatgcggata ttctcgattt ttaagcgctt
    18601 tttataataa aaatagatat gtctactaat taaaactgta gaaatattta taaaggcata
    18661 agacaaattt acctacaatt tttagtgttt agattctaaa aaaataaaaa taattataat
    18721 tgagttcata attttaaaac ttattgaata taattatatg tcggttaaag acgtatgaaa
    18781 ataaaaggaa tttacaagtt atgtgttgta tagatattgt atatgcagca tgtaataaat
    18841 cttagcacta tttatattct atacaaaaag atatttgaag ggagattaaa aatgggaata
    18901 ttagaaggcg ctgcaatgat aagagagatt gcaattaaaa tagctaaaga aaaaggtatt
    18961 acagaacaaa aggcatggcc cgaagctgta aaagaattta aagaaaaata tgaacttgta
    19021 ttataaactt tgactgtaaa actgtctcta ttttattgag acagtttttt atattgtaac
    19081 attcatatta cgaagaaaga tatatataat tttagattcc ttgtaacttt aatttaaaat
    19141 gaaataattt agactaaaaa cagtattaat aaattttatt tatcgtataa atttgttttt
    19201 aatattattt ttaaggtata aatcttatat attagatata aattttggag gtatatgatt
    19261 tgaataaaaa acttgaaaat agatgctcat ggcaagaata ttttatgaga ctgtgcgaaa
    19321 cagtagctga aagaggaact tgtgatagag cttatgtagg agctataatt gtcaattcag
    19381 aaaacagaat agtgtctact ggatataatg gtagtatttc tggagataag cattgtagtg
    19441 aagttggtca tgaaatgaga gatggacatt gtattagaac cattcacgct gaacaaaatg
    19501 ccctttatta ttgtgcaaaa gaaggtattt cagttaaaga ttgctctatt tatgtaactc
    19561 actttccttg cttaaattgt actaaggcta taattcaagc tggaattaaa catatatatt
    19621 atagaactgg atatagaata gatgaatatg ctataaaatt attgcaatca agtaatgtct
    19681 tatatacaaa attataattt taacattatt tacttaatat tctatatttt tacaaaatgg
    19741 gttataataa aagtataaga tataaaaaga aacaaaattc taggttatgc atatattaaa
    19801 tagaagttaa atttaattgt aaaggagatg ttagtttgaa agtagtaata ataccagggc
    19861 acactttaat tggaaaaggt acaggagctg ttgggtatat aaacgaaagc aaagaaacaa
    19921 gaatactgaa tgacttaatt gttaaatggc ttaaaatagg tggagctact gtttatacag
    19981 gaagagttga tgaatcaagt aatcatttag cagaccaatg tgctatagca aataaacagg
    20041 aaactgattt ggctgttcag attcatttta attcaaatgc tacaacttca actccagtag
    20101 ggacagaaac aatatataag actaataatg gcaaaaccta tgcagaaaga gtgaatacta
    20161 ggttagctac agtattcaaa gataggggtg caaagtctga tgttagaggt ctttattggc
    20221 ttaatcatac tattgcacca gcaatattaa tagaagtatg ttttgtagat agtaaagcag
    20281 atacagatta ttatgttaat aataaagata aagttgctaa attgatagca gaaggtatac
    20341 taaacaaatc tatatcaaat tctcaagggg gaggggaaaa taaagtgtat gaaaatgtaa
    20401 tcgtttatac aggtgatgct gataaagtgg ctgctcagat tttacattgg caattgaaag
    20461 attctttaat aattgaggcg tctagttata agcaaggttt aggtaaaaag gtttatgttg
    20521 taggtggaga agctaataaa cttgtaaaag gtgatgtagt aataaatggt gctgatagat
    20581 atgaaactgt taaattagca ttacaagaaa tagataaatt ataaaatcat gattatttta
    20641 taaaaaataa ataagttagg ataaaaaaat gataagaaca aaagttgtag agttgatagc
    20701 aacagtatgc agagaaaaca aaccacataa atgggttgat gaaaattata ctccttatga
    20761 taaaagtggt aaagttgaat taatgtcaat agaagattta aatgaattaa tatcaagcag
    20821 tggaagagca gattttcttt atagcagtag attacaaaag cttctaaatg aggtttatat
    20881 aaatcaaagt agagcatctt atatatcagg ttgtggatta ttttggagtt cgtattggga
    20941 tatacttgaa gaaaaatttg aagaatggct atataattct tatatctttt ttgatgaaga
    21001 tgatgaatat ttagaaggaa tggaagattt tgagcttgaa tgtaaagatg ttcttatgga
    21061 tgtaattgaa acaacaagca tagatatata tgttcaaatg ataaagagga atattaccaa
    21121 ttattaaaaa cacatagtgt caaatcaagc taataaaaaa cgaccttata aatgctattt
    21181 taaggtcgtt taaattatat cttataggct tattttatat taaatttatt actttttatc
    21241 tagaaaaata tttttaatta tagtcaatat atcgactata acatccatat ttgatttgac
    21301 actgtcttta gtaacaagaa aatctgctgt aacttcagta actacttctg ttacatcttt
    21361 catattttct cctacttctc caaaggtttc tacaacatta ggaagattat ttaaagttgt
    21421 atttatattt tgagtatttt catttaacat agttccaaca ttatttaaaa tcttatgtag
    21481 tttaacaagt acaataatta aataaactaa agcaatacaa gcaagtatag ctaataatac
    21541 atatattata cttatgttaa tcgttattgt attgtccata ttattcctca gtaacactaa
    21601 ctggttcaac tatatctatt attttatctt cctcactaga attttcaaca ctctttttgt
    21661 tatctatata tttttttatt tttttctttg attctataaa gtttcctttt ttatcctcta
    21721 gcttctcaga tactttgcct tttacatcta cagttttcat atttatcttt tcagcaattt
    21781 gttgtgaagc atcttttata tcctctcttg tttcttttcc agatttagga gccaaaagta
    21841 ctccactcac tgcaccagta acagctccta ataccacacc agctgtagca attttagctt
    21901 tcttaacttt ttcagctctc tgtttagctt ttcttttatc ttctattttc ttcgatagat
    21961 tcatgtttaa tcgctcctta ttataatatt tctaaacatt ataatacatt ttttaccata
    22021 atgatatagt ttctaactaa atttttaaaa atcaataaaa attcttttta attacttcct
    22081 attcattaca atttaaattt ttataaggat tttctatata tttttctttt attaatatat
    22141 aatatgtatc acatatagat tataaatatc ttatttaatt agtttaatgt atataactga
    22201 aaacttttag tataaatgac cttcaatctt tctatataga ttaaattagt atctcaaaaa
    22261 acaataagag aggaattaat cctctctttt taatttaatt agatttggca gggcggcgta
    22321 tcctgcatct ctattaacta ctctatagta gcgtattggg tgccttttcc aacctcaaat
    22381 ctaactaata aatatctacg tgtatattaa tattataact tatataataa tatttttcaa
    22441 tattttaggg aaaattaata atattatgtt aaccatcata ttgttttact cttccactgt
    22501 ttactctact ttctaatttt gcttctttta tagcatacat tgaagataca tataaatatc
    22561 ctttttttgt atctaattct gtagctacta aaatataatc atcaattttt tttataaact
    22621 ccacactttt tccaggtttt ttaggatgac ttcctatata ttcaggtgac tttaatacca
    22681 tttttatagt atctattata tcattaaaaa tatccttact cagttgacat ctatgttttt
    22741 tctttatatg ttttataaca ccagaagaag cataaatttt accagtatat tcaattcctg
    22801 caagttctgc cgtttcttca tctatgattc caacaacttt gtctgtagac atataaagca
    22861 cattcctttc taagataatt tactattaat actgtaaaat ttatttaaat taaatatcta
    22921 tatttaaagt atagtttatt ccaaaaagaa aagatagtat aatatagttt tttcatatat
    22981 gactttatat aatccctttt tatataattt ataaatggca aataaggttc tattttcaag
    23041 gtatttttag aaattgttta atttctttaa gttttattga gtattcttgc ttctttataa
    23101 aaatataatc tattgtctat attatataaa acgttttctt ttaaagtttt ctgtgataat
    23161 attatttata tataaaataa atttctaata ggaggaaatc atgaacaatc aacaacagga
    23221 agtatataaa aaattagatg agttaagcat accttatgag gctgtaaatc atccaccagt
    23281 ttatacaatt gaagaaatgg aagaattaaa aacattacat atggaatttg ttgtaaaaaa
    23341 cctatttctt cgtgatgcta aaggaaaaga acatttttta gttgtattag gtaaagacaa
    23401 aaaagcagat ttaaaagata ttcgtcaaca aattgatagt aaacctctta gttttgcatc
    23461 agaagaaaga cttcaaaaat acttgaaact tactaaagga gctgtgactc cttttggtat
    23521 attaaatgat aaagaggctg ttgtaaaagt tgtatttgat aaggatttat taaaaatgga
    23581 taaaataggt atacatccaa atgataatac tgctactgta tttttaaaat ttgaagatat
    23641 gaaaaagctt atagaagaaa atggaaacga aatatactac gtagaagtat aattgcaact
    23701 taaaaaatgg caaaagcaac gaatgctttt gccttcttac tactggtgta attaatacca
    23761 ctggtataat catctccatt agtgtaatta ttttctacaa ctttttttct acaataatga
    23821 ttatttatat ttacttatct tttttttgca gatacaagta acatcatagg tctacgtagc
    23881 tcatctttca tatcaggaat tgtatctaac agtttttctt ctggttgagg ttcaataatt
    23941 tctaatattt caaatcctgt tttcattaac gtatttaaat aagttgttaa tgttttatga
    24001 tattttataa cctcttctcc tagaaaattt gacttacgta ctccttcttc aaaatatcta
    24061 tctactggcc agtgtagatt atttccatct ttatcacagt accactcttg acttccatat
    24121 gcagtaaata taggatgttc aacagaaaat acaaaattac ctttatttga aagacaatta
    24181 cttatattct tacatatatc ttcaaatgat tgaatataat gaaatgccaa ggaactaata
    24241 actacatcaa aactatcttt tggaaaatta atatcttcaa taggcataca tatgtaattt
    24301 atattatcaa gttgcgtttt gtttctagct tcttttaaca ttttttctga aatatcaact
    24361 ccaacagcag aaattgctcc attctcaact gcatattgac aatgccatcc aaatccacat
    24421 cctaaatcta aaactctttt tcctttgaaa tcaggtaaca ttttttttaa aacatgccac
    24481 tctccagcac ctgctaatcc atttgtagaa cgttccattt tactgtattt attaaaaaat
    24541 ctatcatcat catatttatt ttgtttcata aagtttcctc cattttaaat atattcactt
    24601 agcaacactc tattaaatac aaaatataag tttttatcac ttttatataa aataataaaa
    24661 gtttctataa ac
//
LOCUS       DAEPUT010000059        24354 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.061, whole genome shotgun sequence.
ACCESSION   DAEPUT010000059 DAEPUT010000000
VERSION     DAEPUT010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24354
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.061"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            83..1195
                     /locus_tag="KRL22_002562"
     CDS             83..1195
                     /locus_tag="KRL22_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1273035.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(1403..1879)
                     /locus_tag="KRL22_002563"
     CDS             complement(1403..1879)
                     /locus_tag="KRL22_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273036.1"
                     /translation="MVKKRLVAVVLSLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(2078..3703)
                     /locus_tag="KRL22_002564"
     CDS             complement(2078..3703)
                     /locus_tag="KRL22_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1273037.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(4041..5060)
                     /locus_tag="KRL22_002565"
     CDS             complement(4041..5060)
                     /locus_tag="KRL22_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HBH1273038.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(5057..5626)
                     /gene="mocA"
                     /locus_tag="KRL22_002566"
     CDS             complement(5057..5626)
                     /gene="mocA"
                     /locus_tag="KRL22_002566"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBH1273039.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            complement(5733..6455)
                     /gene="yqeC"
                     /locus_tag="KRL22_002567"
     CDS             complement(5733..6455)
                     /gene="yqeC"
                     /locus_tag="KRL22_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBH1273040.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIENI
                     KEYESEIEIFYGSVKQKFCVRY"
     gene            complement(6638..7915)
                     /locus_tag="KRL22_002568"
     CDS             complement(6638..7915)
                     /locus_tag="KRL22_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1273041.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(8054..10360)
                     /locus_tag="KRL22_002569"
     CDS             complement(8054..10360)
                     /locus_tag="KRL22_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1273042.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(10353..11147)
                     /locus_tag="KRL22_002570"
     CDS             complement(10353..11147)
                     /locus_tag="KRL22_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH1273043.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDEKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASTLVKRMYNAIEEGMYND"
     gene            complement(11254..12612)
                     /locus_tag="KRL22_002571"
     CDS             complement(11254..12612)
                     /locus_tag="KRL22_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH1273044.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     ASGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(13959..14882)
                     /locus_tag="KRL22_002572"
     CDS             complement(13959..14882)
                     /locus_tag="KRL22_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273045.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTVMKEDMSEVKQEINVLKEDMSEVKQEMIVMKEDMSEVRQEINIMKEDISEVRQ
                     EMTVMKEDMSEVKQEINVLKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEI
                     NVMKKDMSEVRQEITVMKEDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIANEKLYG
                     IEIKIDSLECEDKSMKEIQIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIK
                     EDIAEIRRDLNLVELATSKNWSDIVKLKSVK"
     gene            complement(15112..16197)
                     /locus_tag="KRL22_002573"
     CDS             complement(15112..16197)
                     /locus_tag="KRL22_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH1273046.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(16233..17546)
                     /locus_tag="KRL22_002574"
     CDS             complement(16233..17546)
                     /locus_tag="KRL22_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1273047.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAHVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKRAIVKEMKEVACEFWKF"
     gene            complement(17547..19838)
                     /locus_tag="KRL22_002575"
     CDS             complement(17547..19838)
                     /locus_tag="KRL22_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1273048.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDTKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGKTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMVMKKLNQGGK"
     gene            complement(19828..20622)
                     /locus_tag="KRL22_002576"
     CDS             complement(19828..20622)
                     /locus_tag="KRL22_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH1273049.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLENELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(20661..21107)
                     /locus_tag="KRL22_002577"
     CDS             complement(20661..21107)
                     /locus_tag="KRL22_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH1273050.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVEGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(21179..22585)
                     /locus_tag="KRL22_002578"
     CDS             complement(21179..22585)
                     /locus_tag="KRL22_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1273051.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(22603..23973)
                     /gene="hydA"
                     /locus_tag="KRL22_002579"
     CDS             complement(22603..23973)
                     /gene="hydA"
                     /locus_tag="KRL22_002579"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH1273052.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEEIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISANKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(24106..>24354)
                     /locus_tag="KRL22_002580"
     CDS             complement(24106..>24354)
                     /locus_tag="KRL22_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1273053.1"
                     /translation="EEDEFVQAAYKGLKEAGIDSEITQYSFCTNGSHYAGEAGIKTIG
                     FGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSVYGK"
BASE COUNT         7555 a         4582 c         2554 g         9663 t
ORIGIN      
        1 tgtatgcaac tctatttcaa aattattttg tgatatatat atgttataat aaatgtataa
       61 aattttgatt ggtgggttat atatgaatgc atttattaga aaaagaaata aaaactatgt
      121 tgtttacctg gaatttgaag atgaaaagac aggtaaaaga aaacaaaaaa atatgggtac
      181 ttttgataaa aaaagggaag caagtaaaag actaaatgag gtaaaagaaa gcttatataa
      241 tgatggtttt ttagtaccaa gcgaaattac agtgtcagaa tttctattag attttctaaa
      301 taaatatagt gaaaatatat ctttagctac atataataat tatgttagta tttgtaagaa
      361 ttacattaat ccatctattg gaaaatataa aatacaagac ttacatccgg ttcacataca
      421 aaactacata gataaactat cttataaact aaatcctcaa tcaattaaga ttcatataaa
      481 tatattgaaa cttgcaataa aaagagctta tagactcaaa ttaataaaag aaaatgttat
      541 ggatagtata gaggctccaa gatataaaaa atttaaaaat gagatttatg atagagaaca
      601 aatgataaaa ttattagatt tagcaaaaaa tacagaaatg gaattaccta ttaatttggc
      661 tattggatta ggtcttagaa tttcagaagt tttaggtcta acttgggata atattgattt
      721 tgaagaaaat acaataacag taaataagat aacttcccga attaatggtt ctgttattct
      781 caaagagcca aagacagaaa gctctgttag aaaaatatct tctcccaaag aattaatgtc
      841 tttattaaaa gaatataaaa taaaacagaa taaaaattta ttaaaatctt ccattagaaa
      901 taataataat ttgttgtttt tcaataagaa atgtgaacct attgctgaag atgttatgag
      961 taaaaaattt aaaagatttt tagaaaagaa tgaattacct catattagat tccatgattt
     1021 aagacactca catgttactt tacttataaa ttctaaagta cctataaagg ttatatccga
     1081 gagagtagga cactcaaata taagtactac tctaagcgtt tattctcatg tacttaaaga
     1141 aatggataaa gaggcttctg acaaaatttc tgaaagttta tttaatgcta attaatatta
     1201 atttatctta gctttaaatt agcttagctt attgagatag attcattaat attaaatgta
     1261 tctatctcaa attaataact acttaaataa tctgttttat tttaatttat cgcctcagtt
     1321 attatacttt tttacgaaaa attatacttt acaataaaaa agatattccc ttatagaaaa
     1381 tatcttttta aatactatat tattatatac ttgctaacat tggaatatct aacatcttct
     1441 tcattacatc atctactttt tttgctttat attcattgta tccaattaaa tatccttttt
     1501 catatgaact ttttaaaatc tctttttcat ataaattatc agatttggct tctgtgacac
     1561 ttaaattata aagcccttta cacccatctt cataaccttt attataccct ttttctgcaa
     1621 aatagttttt atgatttttt tcgttatgta ctgaagatat tgttactcca gaattttctt
     1681 ttgtactagc ataaggacaa aaacctttat tgtgttgatg tgctgaatgt cctccacaat
     1741 aataacgtgt taactctgat ttatttttat tatgatgacc tcctgatgaa ttatgccctc
     1801 ctgagtgagc atatgaaaaa ttccctacac taatcatagc taaactcaat actacagcta
     1861 ctaacctttt cttaaccata atctattccc cccaaaatgt tatatatttt tattatatca
     1921 tctactatat tatatttaaa ttcttaatat acaaaatatt actctattct gctaataaac
     1981 atgtttaaac aacataaaaa acctcctaat atttgattaa aattttacac actcatgcat
     2041 agcatgtctc aaatattaaa aggttttata ctaataatta tttatctttt ccatacattt
     2101 tagctaattg gtcttgtatc tctttacttt ctaaatactc atcaaagtcc atttttctat
     2161 ccattattcc atttggagtt atctctataa ttctatttgc tatagtagat ataaactcat
     2221 ggtcatgaga agtgaataaa agtactcctg ggaacttttc aagtccttta tttacagaag
     2281 ttatactttc taggtctaag tggttggtag ggtcatctaa tacaagtaca tttgcatttg
     2341 aaagcattag cttactaagc atacatctaa ccttttctcc tccagatata acttgagctt
     2401 cttttaatgc ttcttcacct gagaataaca ttctacctaa aaatcctctt ataaaacttt
     2461 cacttttttc ttcagagaac tgtctaagcc agtcaaccaa agaatattct actccgtcaa
     2521 aaaacttatt atgatttttt ggaagataat cttgagaagt agttactccc catttatact
     2581 ctccactgtc tggttcaagt tctcccataa ctatgttgaa aagtgcagta gtagctattt
     2641 catctcccat aaatactact ttatcatctc tatccaatct aaatgacaca ttatcaagaa
     2701 ccttaacccc atctatagtt ttagttaaat tgtgtacttc taaaacttca ttcccaattt
     2761 ctcttgcagg tgtaaatcct acatatggat atcttcttct tgatggttgt atatcttcaa
     2821 cttctaattt ctctaactgt ttctttcttg atgttgcttg tttagccttt gaagcattag
     2881 aactaaatct agctataaat tcctttaatt gagctatctt ttcttcagtc tttttatttt
     2941 ggtccttagc caattgtaaa gccaattgac ttgactcata ccagaaatca tagtttccaa
     3001 cgtacatttg tattttacca aaatctacgt caactatatt agtacatatt tgatttagga
     3061 aatgtctatc atgtgatact attataacta tagattcttc taaatccatt ataaaattat
     3121 ttaaccagtt tattgattta aaatctaagt ggtttgtagg ttcgtccatt aatagtattt
     3181 caggcttacc aaaaagtgat tgtgctaaca ataccttaac cttttcccca ccaactagtt
     3241 ccttcatttg tttgtaatgc atatctttcg ttatgccaag acccataagt attttctcag
     3301 cattagtttc tgcatcccat ccgtcaagct ctgcaaactc accttcaagt tcggcagctt
     3361 ttatcccatc ttcttcatta aagtcttcct tcatatacaa tgcatctttt tctttcatta
     3421 tgttccaaag tctctcatga cctcttataa caacatttaa aacagtttct tcttcatatt
     3481 caaagtggtc ctgttttaaa actgacattc tttctttatc agttatagat atactacctg
     3541 tattaggctc tatttctcct gataatattt ttaaaaaagt agattttccc gcaccattag
     3601 ctcctattat tccatagcaa ttacctttag tgaattttaa gttaacatct ttaaatagtt
     3661 ccttatcacc aaatctaagt ccaacacctg taacttgtaa cattaatata ttttcctttc
     3721 tttttgctca taatttattt tatcataaaa ctttgataac atttttatta tatattatca
     3781 cgtaaatagt atatttttta tactaaattt gtgaaatatt tattaaaata atactaaaaa
     3841 ttgtaaattt ataaaaatta acaatctctt atattatact tataaagaaa tcaaattgca
     3901 actttattca ttcttttaca cattgaaaat aagttattat aatttctaaa taaatatgct
     3961 ttttttaaaa catcattcta gctgttttgt ttcatattta aaaagagtac ttaatttgta
     4021 aatactcttt tttaataact ttatatttta gcaaaattac atgcaggata agtacataca
     4081 tcacagttca tacaaaggcc accatgacca tatctagcta tatcatactt atcaagcttt
     4141 tcatcaatta aaaccctaga taaaactata tcaaatactg tagttttgtg atacattgcg
     4201 catcctggta tacccataat tggaacttct ccataataag caagtaaaaa catagctcct
     4261 ggtaatattg gtgaaccata tgtcactaaa tcagctccag tttcttttat agctgttggc
     4321 gtaacatcat ctgggtctac actcatccca ccagtacaac agataagttc tgctccttga
     4381 cttataaatt cttttattgc actctttata atctctttat catctgggca tatagtctgt
     4441 cctataactt cacaaccaaa gccttttact ttttcttcta ttactggtcc aaatttatca
     4501 acaattctgc tataaaacac ttcatttcct gtagtaacaa ttcctacttt cttaggttta
     4561 aaaggtacta catttactat ttttctatta ccaactactt tttttgcatc ttctaatttt
     4621 ttctcatcta taactaaagg tatcactctt gttccagcta cttttaaacc tttatttact
     4681 ataaaattat tatgaagagt agccatcatt atttctccaa cacaattcaa atcaaaaagt
     4741 gcatcaacat ctatctttaa tagaccatca catgctgcta taaaatctat tttcccttct
     4801 tttatttcac taaaatctaa attttctcca gcagttagtt cttttaaaaa caatgctcct
     4861 tcattttcat gaaccattcc ttctgacttt tcccatacat acaaattatc tttaccaaga
     4921 gataataaca ctggaatatc ttcttctttt actatgtggc cctttttaaa ttttcttcct
     4981 ttaaattctc caggtattat ttgagttata tcgtgacata aaacttgtcc aacagcatct
     5041 atagttttta ttagcttcat aatttacccc caattctctc ataatccatt tttgtatcga
     5101 tatcaaataa catttcttta ggaacttcta catactttat ttttgatgaa ttttttaaaa
     5161 tggttttacc tttttcatct tctttaagtg ccaacaattc ttctttctta ctatatggga
     5221 atatgactgg atttccacac atatctttgt atcttggaat tactataaaa tctctatcta
     5281 atttaaaagt atttataatt ttatctatat ataagttatc aataaatggc tggtctccta
     5341 caaagaacat ataaccatca cattttgagc tatttaaaac tcctaatttt atagattcac
     5401 tttgacctat atttgcattt ttattatcta tatattcaaa accatattta ttacacaata
     5461 acaaaacctc ttcatattga cttactacta caacttgatg aaaatcaatc ttgctaactt
     5521 ctctaaatac atgttctatt atagaacagc ctttataatt taataaaagt ttatttgctc
     5581 ccattcttct ggcaaagcct gatgccatta tcactgcatt tatcatatat atcatccttg
     5641 gtatttataa tatattgata gttctatgat ttttataata tctctattga tattatctat
     5701 atatataata tcatataaac tattttaata cttcaatatc ttacacaaaa tttttgtttt
     5761 acacttccat aaaatatctc tatttcactt tcatattctt taatattttc tattaatttt
     5821 atagctaaat ttttatattt ttcattttca actttattaa taaataatac tctttttcca
     5881 gaataatttt taaataatcc atttggattt aatactatat tttttaagtt ttcaatactt
     5941 actgtagaac tactattaat actacttgta tctaaatttg ctattttttt aaatatttct
     6001 actctatgta tattctcttc attaatattc attccaaatg atgttatatc taatatccct
     6061 atggtttttg tagttttatg atatactact ggttctttag cattccaacc tttaagtttt
     6121 tttctctttg agccatctcc ctctattaaa actaaatcaa attggtctac aatttcatcc
     6181 aaaatagagg aatcaatact tactaattta ttttcattat ttatataact accacatact
     6241 gttattccat gacaaataga tggaataaca gttccatcta ttgtaataat tatattgtca
     6301 taatcgtttg gtacatatat tttagttgtt gttgtaagaa gaactttcaa tttatctcta
     6361 taaaaatttg caaaatagtt tataaacgaa gtttttcctc ctgctccaac tacagttatt
     6421 atttcattct tttctattat atttgatagt tccacacttt cacctcttat aaccagtttt
     6481 ctaatctctt aattattata gttagacctt tttagtaaaa gtgatttttg aaattccata
     6541 aactcgaaag taaatagatt ctgttgtaaa caacaaggcg gatccaattc gccgctaagc
     6601 tgtaagctta cgctatcagt ttatctttta aatataatta agatattctt actctctgtg
     6661 gttgctttaa tatttgagga ttattctgta aattagataa attaactact tgtgattttt
     6721 ttagtatatt aagactcgca tttacatctg catttataat gattccaaca ctggatttgt
     6781 actgtccacg cgttattctt tcccctttaa agtcatattt tttaacattg tccacattga
     6841 tatcaggtag aaaatcatca gcaaaaaaat ctgatttact agtatagctt tcttcttgcc
     6901 taataaaatt gatatttttt attttacaca gatattctaa ttttcctttt atctctccaa
     6961 atgggattct tataaaattt ctatatattt ttctctccat attatcactt ttttctaact
     7021 tagcattata tcctacaatt aaatttccaa tattattttt tacacaataa tcaattatat
     7081 aaaaacaggt tttatttaca tagtctttaa cttgattatt tctcttattc caaactttaa
     7141 attgttttct tgttattgca gttatattct tttttaattt taaggcttct attttatcat
     7201 tctgtttgtt tgcccactga ttcacagatt ttagcctttt tccatctatg ataaaactat
     7261 cacctaaatt ggtaacacat gtacataaat tttctaaacc caagtctata gctagtgcat
     7321 ttttttgatt tgaaacttcc tctgattttg gtatttcata acaatactga atttcaaaga
     7381 acctagcttt atgtttaggt attattctta tttctttaat ttttttctct agtatatttt
     7441 gtggaacttt tatacttact ttcccatata gttttttaaa tgctggagac ataggtacat
     7501 ttaaaatccc atcttctttg attcttattt gacctattat tatgctaaaa aatccttctt
     7561 tatctaaata tttaggtgat tttatccctc taaagtcata ttttccttct ttggctaatt
     7621 taattaatcc aaaaaatgac ctaaacgaac tgtctacttc ttttaatatt tgttgcgcta
     7681 tattactatt gagaagctta tagttctcat tttctttgca tacatgataa ttagcttcat
     7741 agttaagatg ttctccttga ttgaaataat gctgtcttac attatatgta ccaacattat
     7801 ataagttctt agctaagaag cacatctctc gtagagcttg atattctttt ttagttaagt
     7861 tttttaattg ttgtctctga gttccatagt gtatattttt tattctgttt gacatgaact
     7921 cacctccttt agaatatact ctactagaca ttatatacgg tatttttaca aaacaccata
     7981 tataatgtcc atttaattac tttattttac aaaataattt aaatttactt gcttttatac
     8041 accttattat ttattataat tgtttattat tatttttcat acccatataa actttttcaa
     8101 aagtcatagg aagctctctt aaacgaactc ctgtagcatt aaatattgca tttgctatag
     8161 ctggtgctgg tgtatgtata actatttctc ctaatgattt agcaccataa ggacctcctg
     8221 ggtcgaaatt ctcagcaaaa tctaccaata tatttccaac ttcttttttt gtaggaactt
     8281 tatactgtag gaaactatct gttaataatc taccatcttt atcaaatata gggtcttcat
     8341 acattgcaaa ccctataccc atcatcacac caccttctac ttgtattcta gctaaagttg
     8401 gatttataac tgttccacaa tcaggtacac atgcaaaatt tatgacttta tattcgcctg
     8461 tatttttatc taattctatc tctgcaaatc ctgctataaa tggttttatt tttttcaaca
     8521 tgccaaaaga ttctgttgct tccaaaacta ctggtacatc atcactagca aatcctattc
     8581 ctccaacaga ttctctaccc aattcctcta atagaacaaa cttgctatta tcgtttttaa
     8641 caaaaaccct gtcttttccc aactctaaat cttctttttt aaatcctagc tttgactctg
     8701 caactgaaag taatatatct tttaatttat ttgctgtctt tattgttgca tttcctgtaa
     8761 ccgttgtcgt acaagaagca aatgctcctg tatcataggg acataagtct gaatcacctg
     8821 tataaataga aattctatct acagtagtat ttaaagcttc cgcagcaatt tgagcttgaa
     8881 ttgtatcagc cccttgacct aagtcagcaa gaccagataa tagtttatat gtgccatctt
     8941 catccattct tatagtgact gttgccatat ctacacgcgg tataccagaa ccatgatttg
     9001 ctactgccat acctactgct cttactttgt tgtttcctat atctttacat ggatatttat
     9061 cgtcccaatt aattaatttc ttgccctttt ctatacattg tctcagctca caacttaata
     9121 tttcgtcttc agctgctttt ccattggtat acctatctat tatattttta attctaaatt
     9181 caagtggatc cattccaatc ttatgtgcca attcatcaat agcactatct attgcaaata
     9241 ttccctgtgt agcaccatac cctctaagtg ctcctgctgg taacctatta gtatatactg
     9301 ttctagcatt aaatctaaca gcatcaatat cattatatat tggtaaggta ttgtgtccag
     9361 attcggaaga aacagagaca ccattcccac cataagcacc tgtattgttt aatgacttta
     9421 gctctattgc ttttaaattt ccttctttat ctgcaccaac tttaacatca aaaaacattt
     9481 catgtctact attagaacct acaaaagttt cacttcttgt aaatacaaat tttgctggtc
     9541 taccagtttt catagtaaca aatgcagtaa atatatctgt tgctgctata ttctttcctc
     9601 caaatccacc acctattcta ggtttaatta ctcttatttt tgaagatggt atacccaata
     9661 cttttctaag tattctcttt acattgtgtg gtgattgtaa tgatgaaact acaacaattc
     9721 tatcatttat atctttatat gaatatgacc tatgagtttc catcatgcaa tgcgattgac
     9781 tttgggtttt gtatgaagat tcaaccacaa aatcactttc tttaagctta gcttcaacat
     9841 ctccaaattc aaaaaattct tttgatacta tattattttt tgcatccaat ccaaaaggat
     9901 atggctctac tatgtctttt tctggatgta taacaacttc atttccttct gcttctcttg
     9961 catcaaacac aggctttaaa acctcataat ctacctttat catttttaag gctttaagtg
    10021 ctgttttctc atcttcagca gccactaaag ctacttcatc tccaataaat ctaactgtat
    10081 cttcaagtaa aactctatca taaggtgatg cttctggttc tgtttgacct ggaacacaat
    10141 atctgacctg tggtacatct ttatacgtat aaatacccac aacccctgga attttttcgg
    10201 cttttgatgt atctatattc tttatcttag catgagcatg tggacttcta agtagtttta
    10261 atgtcaaaac atctttatgc ataatgaggt cttcagtata tagaggtttt cctgtgacaa
    10321 ttgctgtact atctatcttt cttatcccct tattaatcat tatacattcc ctcctcaata
    10381 gcattataca tccttttaac taatgtactt gccatatcct ttctgtactc tttactagct
    10441 ctcatattac ttccataagt aagttcctta ctagcaacaa tagatgcctt atctatatct
    10501 ttttctttat ttaatatatt actcgcttca agtgctaatc tagctttttg aggtcttgcc
    10561 ccaattgcta ttttgtaagt atcattttct tttagcattg ctgaatttaa tacagaaaaa
    10621 tctcctgtgc attttcttat tgagtcaaaa acagctattg catctttttt tggtagtatt
    10681 acttcgacca atatatccct acttaattca ctatccaaaa actcacttaa ctctagtatt
    10741 cctttattgt ataatctcac cttcgctcca acaaccaaaa gcgctggtat taagtcagaa
    10801 aagccatact ttgaaaatac acttgcacca attctagccc cttgtctaaa ttgaacacca
    10861 actatattag aaacagcgct tgaaagtatt ccactacagt aattttttat agttttatca
    10921 atttctaaac ttctaagtga agtatctgca cctatcaaaa tatttttttc atcctctttt
    10981 atataattta gatttatatc ttttaaatct atcgctgttc ctatattttt attacttaat
    11041 tttataaatc cacatccacc taaaataaca ttattttttt tagaaattaa aattttatat
    11101 gcttcttcta aactctgtgg aactgaatat tcctttatag taaccatctt atccccccat
    11161 cattaactta ttaaaacaca aaagttttta ataaatcttt tatttatatt tataattgta
    11221 gtatatttaa ttcacatata ttaaaccttt acattataaa cttttatttt tatcctcaac
    11281 cttatcactt ttatttccag gaaattttac catatataaa gcttgaatta ttatggctac
    11341 cattgctcct gaaactacac ttgaatctgc aagtaatgtc tctataaatt ttggaaattt
    11401 ttcaagaact tgaggagcta ccatgaatcc aataccagaa gccatagaaa gacctaatat
    11461 catgctattt tcttgattaa atccatccat actaacaagt cttaaaccag atgttgtaag
    11521 agttgaaaat ataacgagtg ttgctcctcc aaccacacag ggaggaattg ttcttattaa
    11581 attagctaat aaaggcgata ttcctgccaa aaataatcca attcctccaa tagctagtac
    11641 aaatttactt acaacctttg tattggaaac gattgcagaa ttttgtccaa acatccccat
    11701 tggagttgca gaaaataatg cacctattgt agagagtact ccatttccta aaacagcaga
    11761 agaaagttct tcatctgtta cttgtctatt aagccctcct accgcagaaa gtgtacaagc
    11821 acccattata tcagctatct caactaaata tattattgaa aacattacaa caacttcaag
    11881 tcttatatct agcccaaaag caagtggttt tggaagtgca accaaagtaa actcctgaat
    11941 tgaagaaaaa tttactatac ccaaaattaa tgataaaatg tatccaaaaa ttatgctaac
    12001 taatattgat gcatctttaa ataatccttt tccatattta tttaatccta atatcataag
    12061 agatacagat attccaacta taaaattaat tggattccca aaagtctcat tgcccatacc
    12121 cccagctaag ttttttatag ctattggaaa aagtccaaga cccatacatg caactattgt
    12181 tcctgataca gctggagtaa atataaatcg tattttttta agaccaaaac caattataat
    12241 tattactata ccagctatta tttgagagcc aaataatact ggtagtccat acttacttgc
    12301 aacagatacc ccagctccta taaacatagc tgtagctccc attataactg gtattcctcc
    12361 tcctaattta aaacctttaa acaaaggtat tggatataat tgtaataaag ttgataatcc
    12421 tgcaaaaact aatgcggctt gaatcaataa tgttgacatc ttatgattaa gtccagatgc
    12481 atttgcaatc aatatcgctg gtaaacaact acctattacc attgccatta agtgttgtaa
    12541 ccctaaaggt attgcttcct ttagtggtgg tattccgtct aattcaaatt ttgatgtact
    12601 ttttgctttc ataataaaaa ctcccgttac ataaaactta ttgaattata taaatactta
    12661 aaaatctaat atattaaatt aatgatgttc ataaatatca actatactcc aacatatatt
    12721 taagttttta gtcttaaaaa acagatgcaa taaatttaat tattaacaaa tacacgtatt
    12781 ctttaatttt gtatacatta tataccatgc tttataaata taagagtatt atagctatga
    12841 atttttaatt ttttatagta aatttaattc aatttaaatc tttcaatctt aatcattata
    12901 agttataagt tttcataagt atttacatgt ttcaagtttt aaacatttac ctataaacgc
    12961 tactttatag atgtcacttc aaatccagtg acctcatact ttcatatgag cgtagactat
    13021 ttcttcatct tcagcattac ctgctaagag caacccgttt ccactatcaa tcgcttatag
    13081 tgtactctct ctcgagatag tcgtttgacc ttcctatttc taggcttggc gaccaaatgt
    13141 ccatttttaa gtacttaggc tctcaccata taccatcctc actattgttt ctggttttca
    13201 ccacattcat aaaagtttct ttctatcttt tattgtagtt gcaaggcttt aggatttact
    13261 ggttttaaag ttgtgtccta catagatttc tctatgtacg gggccaaaag tacaatttat
    13321 ttaacatact ttgctttacc ccctgtaaat aatattattt actctttcac tgtttttgtt
    13381 attaaattaa ttaaatatca attaatctaa gcataaaata attatttaat ttaaactcaa
    13441 aatatttatg aatattttat aatataattc tcataagaca gaaaaactta ataagctatg
    13501 tatctcagtt gtaccaatgt actctccttt actatatttg tatctgcaac ataaaatata
    13561 caagtttcta tctatttata gatatatata tctataagca aaatagtaat attattttta
    13621 tagtaaaaat tttattcata ttactattta taatttttat agagcaattt tagtgccaat
    13681 atttgcatac atttgtatag tataaaattt ttatgttctc attgataaaa ttttacttat
    13741 ttcaagcgtt ctattagatt ttatcatcta aattttaggt tttattttta taaattaatt
    13801 gtatttacat aaaaaaaaag acctaaaaac aaatttttaa cggtcttttc tcaatttttt
    13861 attttcattt ctaaaattta taataaatag taagaacact ataaattctt ttatataaaa
    13921 ttcttagttt gtggatgata aattagtgaa ttaaaatact actttactga ttttagtttg
    13981 acaatatcac tccaattttt actagtggct aactctacta aatttaagtc tcttcttatt
    14041 tcagctatat cctcttttat agaattagtg tcacctttta tatatgctat gttatgttct
    14101 atattatcat gagtagcttt atttatttca gaattatgta ataaacttcc taaaatatta
    14161 ttctgttcta tctgtatctc tttcattgat ttatcttcac attctagact atcaatctta
    14221 atttcaattc catataattt ttcatttgct atggatacct cgtccttaat tccattcata
    14281 tcttcattaa tgttatttat tttattttgc ataaagttta cttctgattt aacttcggaa
    14341 acatcttctt tcattacagt tatttcttgt cttacttctg acatgtcttt tttcattaca
    14401 tttatctctt gttttacctc tgatgtatct tctttcatta cagtcatttc ttgtcttact
    14461 tcagacatat cttctttcat tatatttatc tcttgtctta cttcggacat atcttctttt
    14521 aatacattta tctcctgttt tacttccgac atatcttctt tcattacagt catttcttgt
    14581 cttacttcgg atatatcctc tttcattata tttatctctt gtcttacctc tgacatatct
    14641 tctttcatta caatcatttc ttgttttact tccgacatat cttcttttaa tacatttatt
    14701 tcctgtttta cttccgacat atcttctttc attacagtca tttcttgttt tacttccgac
    14761 atatcttctt ttaacacatt tatttcttgt tttacttccg acatatcatt ttttatgcta
    14821 actacatctt catttatagt atataataac tctaaaatct tctcttgcac ttgcatcacc
    14881 atccctatta attattataa cattttacac aaatgctata caatgttaac atatatatca
    14941 gaattattaa aattttaatt aaacaaaatt gattcacttt attacttcaa aactaattaa
    15001 tatctaaaat aactacaaat aaacaaaaat aaggtcaaca acaaaaaagg cttatctctt
    15061 tgagatagcc tttcttattt ttatttaaaa ctttgttttt tataaaataa tctatacatt
    15121 cagctctgaa catgaaattt ttcttccaag tgcttttggt ttacaaactg atatacaaag
    15181 tccacaatat ctacactctt cttcattcaa ttccatctta tcattcaatt ttctcgcttg
    15241 atatgcacaa actctctcgc acatcttaca tttagtacat ttttcttcat cataagtaaa
    15301 ctcaaagcta agtctttcat taacatctcc catatgatta tgtactatac cacaagcatt
    15361 ttctatagta ttatatccta atctattaag attagatttt aaatcatcat gtattttaga
    15421 tattacttgt gcgcctttta aaattactac tgaacatata ccaacaaagt cagcacctgc
    15481 cataatcatt tctaaggcat catctccact tacacatcca cctaagccaa ttattggtat
    15541 attaacttgt ttttttattt catatattct ctgtaaagtt attggcttga tagtttctcc
    15601 acttaaatat cctattccat ttccacctaa taaaggttgc cctgtttcta tgtctattct
    15661 aaatgctggt cctacagagt cacaagcagt tattgcatct gctcctgctt cttctaattt
    15721 tttagcaaaa tcgcctatct catctatcat aggaggaagt ttaactatta caggtatatt
    15781 tactctttcc tttgcatctt taagcattgg tatcaaatct ctatagtcat aagatactaa
    15841 ttcaataaag tcagctcctg catttgcaac tttctctact aattcgctac tttcttcaat
    15901 tgtatgacct attgaagcta tacagacagt cccatctctt ttcatttgtg gtatttcaaa
    15961 atctatccat tgctctggct caaaatctgt ccatttttca ttatttaaaa gagcattagc
    16021 tgtatttcta accatatgtg gtgctggatt tatagctctt tcttttctta tagtcttagt
    16081 cacaactgcc cctgctcctg catcacttaa tatcttgcat ccagctgcac tatatgttaa
    16141 tggtcctgaa cctattataa gtggtgattt taattcttta cctaaaaaat tatacattat
    16201 ctgcttcccc ttttcatata tatttacatt cgttaaaatt tccaaaattc acaagcaact
    16261 tctttcattt ctttaacaat agctctttta tctaaatcaa ctaactgttt ttcttttaaa
    16321 atatgtctac catctatgta tacatttgat ataaattctt ttttaccctg aactactatc
    16381 tggtcaaata tattatcaag agtcacagga gttttaaatt catcttccat aactattata
    16441 tcagccttat taccaactgc tattttacca gaattttgaa gtcctaatac atgagcacca
    16501 tgctctgttg ccattctaaa tactaaattt gctggcatta ctgatgcatc ttcttcaact
    16561 gatttatgca ttaaaaatgc acctctcata acttcaaaaa aatcatttat atatccatca
    16621 gtacccagtg ccacttttat gcctttttta atcatttttg gtactggaga aaaacctcca
    16681 cctacttcac agttgctaag aggcatatga accactttta cacctttttc ttttaatata
    16741 tctatttctt catcatttac ttttacacac tgagatgcta atacagtttc atccaatata
    16801 tctaaatcat tatagtagtc aactgctttt ttgccaaaat gtttttcagc atagtttggc
    16861 tcatatatac tctcacataa atgaaattgc attggtgcat ttaatttttt tgcatcttct
    16921 ttagctttct taataaatct atcagaacat gtgaagcttg tatgtgtaca cattattcca
    16981 tttattaatt tactattttc tctactccac tttattaaat tagaattttc atctaaacat
    17041 ctaagtccat tttcaaagct tattctttca caactttcta aggataaaat cgctttcatg
    17101 cctatttctt ctagtatctt tccttgctca attaaagttc cttcttctgt gtttggagct
    17161 tctagggtat cacaaaaagc taccacacca gattctataa gttctattgc tgatgcttta
    17221 gttgttgcct tcacttcttt caatccaatt ctattttcta taaatggcca ccaatagtca
    17281 tttaagaaac cttcaaagtc ggtaaaatgt acatttgcgg gtattcccct agaaagaact
    17341 ccatattgat gcatatgacc attgacgaat cctggcatta ttatagcatc tgatttatct
    17401 attatttctt caatattttt atattttatt tcaacttctt catttggcaa tatatctttt
    17461 ataatgtcat tttctactac aacagcagaa tttgtatata tttcatcagc agaagatatt
    17521 aagtatttac ttttaatagc aatcatttat ttacctccct gatttaattt tttcatgacc
    17581 atataaactt tctcagaagt tataggaagt tctcttatac gaactcctgt ggcattgtat
    17641 attgcatttg ctattgctgg tgcaggtgta tgaataacta tttctcctaa agatttagct
    17701 ccatatggac ctgttggctc ataattatct acaaaatcaa caattatgtt tcctatatct
    17761 ttttttgttg gaactttgta ttgtaataga ttagaagttt gaagctttcc atcagaacca
    17821 tgtctagggt cttcatacat tgcaagccct ataccttgag ttacaccacc ttcaacttgt
    17881 attctagcaa gtgcaggatt cataactgta ccacaatctg tagaacaagc ataatttatt
    17941 actttaaact cccctgttgt tttatctaac tctatttcag caaatcctgc taagaatggt
    18001 ttagcactct cttgtatacc ataagattca gatgaatata aaacttcttg atttccacca
    18061 ccaacagatt cttttcctaa ttcacttaac aaaacaaact tctctacatc ttcactataa
    18121 caaactctgt cttcatatag tattaaatca tctattggta aatcgagttt cttctgtgct
    18181 acttttaata tcttttgttt taaactttca gcagatttta ttgtagcatt tccagttaca
    18241 taagtagtac aagaagcgta tgcaccagta tcatatggac acatatctgt atctcctgta
    18301 taaacggaaa ttctatcaat agatgtattc aatgcttttg cagctatttg tgcaagtatt
    18361 gtgtcagaac cagttcctaa gtctgaagac ccagaaaaca acttataagt tccatcttca
    18421 tccatcctca tatttactat tgccatgtct atgttggcta taccagaacc atgagttccc
    18481 acagacattc caacagccct caccttattg tttccaatat ccctaacagg gtacttttca
    18541 tcccatccaa taagtttttt acctctaatt atacattcat caagtgcaca acttcttatt
    18601 ggaaaattca ttattccgcc ttcagtttgt ttttttataa tattctttaa ctttatttct
    18661 gttgggtcca tattaagttt atgcgctaat tcatcaattg cacaatcaag tgcaaatgta
    18721 ccttgtgttg ctccatatcc tcttaatgct cctcctggaa ctaaattagt atatacagtt
    18781 ttcccatcaa attttattgc aggtacatta ttatatgttg gaagtacatt atgacctgat
    18841 tcagagcaaa ctgaaggtcc attatcgcca taagcgcctg tattgttcaa tgctttcata
    18901 tctatagctt ttatgtttcc ttctttatct gccccaattt ttatatcaaa aaacatctga
    18961 tgtctagtat tagtcattgc aaaagtttct tctctagtat aaattagttt tgctggtctt
    19021 tttgtcatcc aagttacaaa tgatgcatat atctctgtta cagctatgtt ttttccacca
    19081 aaacctccac ctattcttgg ttttattact ctcacttttg aaagaggtat tcccagtgct
    19141 ttagaaacct gtcttctcat atgataagct gattggtttg cagaagttac tactaatctg
    19201 ccattcgtat ctatatacgt ataagctcta tgagtttcca tcatacaatg ggcttgtgat
    19261 tgagtcatat aagaatgttc tactattaca tcactttctt taaactcttt ttctacatcc
    19321 cctttaccca ttttttctct cgatacaata ttttttgtag catccaatcc aaaatcaaat
    19381 ggacaaaaca aatcatcttc ttcatggatt aaaattttat ttccttccga ttctcttgca
    19441 tccaatatag gagtcattac ttcatattca acttttataa gtttcatagc tttaatagca
    19501 gccctttcat cttcagcggc tattatagca acttcatctc ctacatatct aactacgtct
    19561 tcaagtatta attggtcatg aggtgatgct tctggatatg actctccaac cattgaatat
    19621 ctataatttg gaacatcttt gtaagtaaat atgtttacta caccttttac ctttaatgca
    19681 ttttttgtat ctatgttttt tatctttgca aaagcatgtg gacttctaag aagcttaatt
    19741 gttaaaacat ctttatgaaa aattaaatct tctgtatata ttggttttcc agtaacaatg
    19801 gcttcactat ctatttttct tacctcttta tttaccatca cactcacctc caatactatt
    19861 atacattctc actactaagg cttttgccat atcttttctg tattctttac ttcctcttat
    19921 attacttcca aatgaaagtt cttcacttga tacttcacca gctttttcta tatcattttc
    19981 taaacttaat atttcacttg ctttataggc aatttttgct cttcttggtc tagcgcctat
    20041 cgcaatttta taaatacttc cttcttttaa cattgctcca tttaatactg caaaatcacc
    20101 tgtacatttt cttatagaat caaatacacc tatagcatct tttttaggta atataacttc
    20161 tattaatata tctttttcaa gctcattttc taaaaaatca gctaagttca taaccccttt
    20221 tttatataac ttaacctttg catctaccac tagtaatgaa ggtattaaat ctgaaaatcc
    20281 atacttagca aatacgctag ctcctactct agctccactt ctaaattgaa ctcctactat
    20341 attagaaaca gcgtttgaaa ttaccccatt acagtaattt ttaataacct tatttaattc
    20401 taaagttctt aaacttgtat ctgctccaat taatatgcta tcatcagttt catttatata
    20461 atctaaagct aagtctttta aatctattgc tgaaccaata tttttactac ctagttttaa
    20521 aaatccacat cctccaagta ttatgttgtt ttttcttgat attagcagtt cataagcttc
    20581 atctaaactt tttggaacta catattcctt tatagttatc atactctctc cccatatcaa
    20641 cttaattttc acttaaaagt ctaagtgttt aaatatttat gtattgctct taattgacct
    20701 ttatatcctg tacatctaca aaggttacca tttacataat ctataacttc ttcttctgtt
    20761 ggattttgaa gctctctttt cattgccaag accatcatta taaatccagg agcacaaaat
    20821 ccacactggt cagccccttc gtctgcaaga aaatctccaa acttctttgc ttcatccaag
    20881 acaccctcaa gtgttgtaat atgctgacct tctactctag cagtaagata attacatgaa
    20941 agcacggcct tgtcatttac catcactgta cataacccac atgagcctgt atcacaccct
    21001 tttttaacac ttacatatcc attttctctt aatgtatctg ctaaaaaatc atctggtctt
    21061 atacttaatt ctttttcttt attatttatg gtacatttga taatcaaata aatcacctca
    21121 aaactcatat ttttaagcta aagttttact atactttttt atgaataaat tacatttatt
    21181 aataaaggct attccattta tgaccttcca ttctattttt tatagttcct cttacacaaa
    21241 gtctctcagc tgtatcttga gcatctttta atgctttctc ttcattagct gtcaatattt
    21301 ttgaatcttc cattattata tttccatcta ctataacact ctctatattt ttcatactag
    21361 aagaatatac taatgtagat accggattat gcataggtat cgcttttggt gaaagcattg
    21421 gattaaatat taataagtct gcttttttac ctatctccaa tgaacctatc tcatcttcca
    21481 ttccaatagc tcttgctcca tctatagttg ccaactcaag aactttttct gctgacattg
    21541 ctaatgggtc acacttatta actttatgtt gaagtgctgt taatttcata agttcaagca
    21601 tatcttgaga gttattacta gcggctccat ctactcctaa actaactgtt attccttttt
    21661 taagcatttc tggcactggt gcaacacctg aagataagta catattactt gctgtattat
    21721 gagacacttt catatcgtat tttttagtaa gttccatatc tttttcagtt agatacacac
    21781 aatgtaccat aagcacattt ggtccaagta ttcctaattt ttctaaaaca tctatgtcat
    21841 attgcccatg caattctttt gctgcttctc tatcaaaagg agtctctgat atatgtactg
    21901 taaataaagc atcatcatat tcttttacta ctctccatag catttcaagc atttcttgag
    21961 aatttgacca tattgctgca ggagctactc ctattttgat tcttccattt tctgtattat
    22021 ggtgtttttc aaacaatctt cttacatctt tttcaaccgt ttctacatct tgcattattc
    22081 caggatgaac tccaaattga gctcctgtat tcatacatcc tcttccaagt attcctctta
    22141 ttcctaattc tttataagca tctattattc catcacaaag acctggctta ctatgaggat
    22201 acatgtagtc aaccattgtt gttataccgc ttctaagtcc ttcaatacat ccaagcattg
    22261 cagcatcata agtatctttt ggctctaaat agttagctgc tggaaatgtc atagtttcta
    22321 accagtcttt aagtaccata tcatctccca atccttttaa taaagtttgg aataaatgat
    22381 tatgtgtatt tataaaacct gggaataaaa ctttaccttt agcatctata atttttttaa
    22441 catcagtata tttactttct atctctttag aatttccaat atcagcaatc ttgttatctt
    22501 ttactactaa tgccccatca aaaataactt ctctctcttt attcacagtt actattatgg
    22561 cattcttaat aagtatatcc atcattctta tttccccccg cattatttag taatttttct
    22621 tttaatatat tgacctgttg gatgttcttt aacattacaa ctttgtacta catgatttcc
    22681 tctcaaaaat acatcttcaa ctttacattt aaccttaaat ccttcatatg gagtataatc
    22741 tacattttgt ttttgagttt tataactaat tgtttcttct ttattgatat ttaaaatgac
    22801 tatatctgca tcacttccta cagctatctc acctttttta ggatacattc caaatatttt
    22861 tgcagcattc gtagaagtaa cttccacaaa cttatttgca cttattctat tttctaagac
    22921 tccatatgta tataaaagtg ctaacctatg ttcaacacca ggtgctccat ttggtatctt
    22981 actaaaatca tcaattccca agtctttttg ccccttaaaa ttaaatgaac agtgatctgt
    23041 gccaactgtt tgaatatctc cactagacaa tccttcccaa aggtaattta tgtcttcttt
    23101 ttttcttaaa ggaggagaca ttacatactt agcaccctca aatttatcct tattatataa
    23161 attgtcttct aataatagat actgtgggca tgtttctact atcatatcta tatttttttc
    23221 tctagccatt tttacagttt caagtgactc cctacaactt aagtggacta cataggattt
    23281 tgaattagat aatttagtta tatcagcaag tcttgaaaca gactctttct caactatgtt
    23341 aggtcttgta agtggatgat attttggctc caaattacca ttttgtatat tttcttctat
    23401 caatacatct agtaaatccc cattttcaca atgaaatcca actatacaac ctaaatccct
    23461 tgctttcttt aaaaccctgt atattgttcc atcatctact ttcatgccat catatgccat
    23521 atacatctta aaagatacta tcccatccga aataagtttt tccatatgat taaatgtatc
    23581 tttatttaaa catgtaattg tcatatgaaa accataatca caataacaat ttccacttgc
    23641 ttttttatga tatgcttcta caccttgcag taggttttcc ccctcattgg cttctgcaaa
    23701 atctagtatt gtagtagttc ctccagctat agctgctctt gttcctgttt caaaattatc
    23761 tgcagttgta atagaacctg cattcatatc aaaatgagta tgtgtgtcta ttccaccagg
    23821 aattacaatt ttacctgtag catcaataac cttatcacca tttatttcta agttatttcc
    23881 tatttcaact atctcttcat cttctatcct taaatcactt atataagtct tatcagaggt
    23941 aattatagtt ccacctctta gtattgttcc catatatacc tcctaacttt taagctttaa
    24001 agtattttct aagtattgta aaactttatt taaaattgta ttttctaaag gtgctatatt
    24061 cagcacctct agactatatt taaataattt attgtgaact aaatattatt ttccgtatac
    24121 agattttaat attccatagt aaccttctgt tcctataaat aactgttctt gctctatata
    24181 ctcatctatt gtgtgagcaa gattttcctt agaaggacca aatcctatag tttttattcc
    24241 agcttcacct gcatagtgac ttccattcgt acagaatgag tattgagtta tttctgaatc
    24301 tattccagct tcttttaatc ccttatatgc tgcttgaaca aattcatctt cttc
//
LOCUS       DAEPUT010000060        23966 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.062, whole genome shotgun sequence.
ACCESSION   DAEPUT010000060 DAEPUT010000000
VERSION     DAEPUT010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23966
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.062"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(269..985)
                     /gene="dapD"
                     /locus_tag="KRL22_002581"
     CDS             complement(269..985)
                     /gene="dapD"
                     /locus_tag="KRL22_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBH1273054.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     NNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(1250..1999)
                     /locus_tag="KRL22_002582"
     CDS             complement(1250..1999)
                     /locus_tag="KRL22_002582"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH1273055.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(2066..2953)
                     /locus_tag="KRL22_002583"
     CDS             complement(2066..2953)
                     /locus_tag="KRL22_002583"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH1273056.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(3070..4071)
                     /locus_tag="KRL22_002584"
     CDS             complement(3070..4071)
                     /locus_tag="KRL22_002584"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBH1273057.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(4496..5377)
                     /locus_tag="KRL22_002585"
     CDS             complement(4496..5377)
                     /locus_tag="KRL22_002585"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH1273058.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            5700..6893
                     /locus_tag="KRL22_002586"
     CDS             5700..6893
                     /locus_tag="KRL22_002586"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBH1273059.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            7099..8217
                     /locus_tag="KRL22_002587"
     CDS             7099..8217
                     /locus_tag="KRL22_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HBH1273060.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            8348..8593
                     /locus_tag="KRL22_002588"
     CDS             8348..8593
                     /locus_tag="KRL22_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HBH1273061.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            8580..9326
                     /locus_tag="KRL22_002589"
     CDS             8580..9326
                     /locus_tag="KRL22_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1273062.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKSEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            9611..10486
                     /gene="hslO"
                     /locus_tag="KRL22_002590"
     CDS             9611..10486
                     /gene="hslO"
                     /locus_tag="KRL22_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBH1273063.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            10877..11677
                     /locus_tag="KRL22_002591"
     CDS             10877..11677
                     /locus_tag="KRL22_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH1273064.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            12205..14445
                     /locus_tag="KRL22_002592"
     CDS             12205..14445
                     /locus_tag="KRL22_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1273065.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNICEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            14859..16394
                     /locus_tag="KRL22_002593"
     CDS             14859..16394
                     /locus_tag="KRL22_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH1273066.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIVIIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            16410..17171
                     /locus_tag="KRL22_002594"
     CDS             16410..17171
                     /locus_tag="KRL22_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273067.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            17509..18378
                     /locus_tag="KRL22_002595"
     CDS             17509..18378
                     /locus_tag="KRL22_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1273068.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            18707..18958
                     /locus_tag="KRL22_002596"
     CDS             18707..18958
                     /locus_tag="KRL22_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBH1273069.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            19070..19849
                     /locus_tag="KRL22_002597"
     CDS             19070..19849
                     /locus_tag="KRL22_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1273070.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(19984..20634)
                     /locus_tag="KRL22_002598"
     CDS             complement(19984..20634)
                     /locus_tag="KRL22_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273071.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(20631..21134)
                     /locus_tag="KRL22_002599"
     CDS             complement(20631..21134)
                     /locus_tag="KRL22_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1273072.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(21183..21698)
                     /locus_tag="KRL22_002600"
     CDS             complement(21183..21698)
                     /locus_tag="KRL22_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH1273073.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            21978..22505
                     /locus_tag="KRL22_002601"
     CDS             21978..22505
                     /locus_tag="KRL22_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1273074.1"
                     /translation="MHEQIDCCERKKIKTINIKGENMRELLKWVSIINRYNTNYIDRK
                     LADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGV
                     KDKRTWHLYPTEKSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDM
                     NEEAKLEAKENGRKI"
     gene            22489..23892
                     /locus_tag="KRL22_002602"
     CDS             22489..23892
                     /locus_tag="KRL22_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1273075.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
BASE COUNT         8880 a         2943 c         4006 g         8137 t
ORIGIN      
        1 cactttatta aattataaaa agtttaatag tttattacat tgatatattg aaaaattgaa
       61 ggaaataaaa atacttgtca gcaagaaata aaaatgatat aagaatgaat aagagaattg
      121 taaaaaaata aaatgattat aaataaaaga taaaaatatt gtaaaaaaga gggtgcctct
      181 ggtgaattaa attcacacag agacaccttt ttaattaatt ttttaaatta gtatattatt
      241 gtttaattaa tagcatagta ctatttaatt aatctaaatt tctaaggtct tccataagct
      301 tagttttgtc agccgttttt tcatctttca tttttataac tttagcagga gaaccagcaa
      361 caacggcacc agcttctaca tcagtagtta caacagcacc agctgcaaca acagcacctt
      421 taccgattct aacaccttca agaataactg cattagctcc tattaaaaca tcatcttcaa
      481 ctataacagg agtagcagaa ggtggctcta aaacaccagc aacaacagca ccagcaccta
      541 agtgaacatt tttaccaaga gttcctctag ctccaataac agcattcata tctaccatag
      601 aaccttcacc aataacagct cctatattta taacagctcc catcattaca acagcatttt
      661 tttctatagt aaccatgtct cttattattg cacctggctc aattcttgca tgttcactta
      721 aagtattttt tagaggaata gcagaatttc ttctatcata ttctacatga gtatctgtta
      781 tatcatttcc atgtttatct aatacttcca ttatatcctc atagtcacct acaaatatat
      841 aagaaccatt atttccaaat accttaaatt tatcagttga ttggaagtgt aaagagttag
      901 tatttacata taccttaaca ggtgttttct ttttaacttc ttttatatac cttgctattt
      961 cataagcatc gtttaaattt accatttgtt aattctcctt gtatttcatt atatttcttt
     1021 tattatatac ttatttgtca attttagtat atacttactt cttattattt atattttatt
     1081 ttagttagtt tttattgtat agacatagta ttaaataaat ttattatata tgtttgattt
     1141 gtattgcgta ttattatatc tatattgcat atgtttgatt tgtattgcgt attattatat
     1201 ctatattgta tatgtttaat ttatattgtg tattattata tttatactat tatcccaaca
     1261 tgctgtccat attataaaat cctggttttt gcttaactaa gtatttggca gcagctatag
     1321 aaccacttgc aaagatacca cgagattgag cttgatggct tattgtaaga acctcattgt
     1381 ctccagcaaa tagagcatca tgttcgccaa caatatttcc acctcttata gcatgaatac
     1441 caacttcatt tggttgtctt tttgcactac gaccatatct accataatta ttttcaacgt
     1501 ttggcaaaac ctcttttata gcgttagcaa tcataacagc tgtgccactt ggggcatcta
     1561 cttttctgtt gtgatgtttt tctattattt ctatatcaaa tccttctagt aatttagctg
     1621 catctttaac caattttact aatacattta caccaagaga catattatat gattggaata
     1681 caggaataac tttagccgct tcacgtattt tgttcatttc gtcatcatta tatccagtag
     1741 tagcaattac taaaggtgtt ttagtcttta aaacgtaaga taagatatta tctaaattag
     1801 agtgatgaga aaaatctata actacatcag cttcctcaac tatagtactc atatcttcat
     1861 aaattttaag gtcgccttca tagctatcca gacctctagc tgcaacacaa accaattcta
     1921 attcattatc ttctcttata gtatcggcta aaatcttacc catttttcca tcataaccag
     1981 ttgctataac ttttaacata atttcctcct atgattaagg gctaactttt gaccaaactt
     2041 actttttacc atgcattaat ctttactatg cattaacttt tagtccaaag ttaactaatt
     2101 ctttctttaa cacttctaaa tttgctgggt ccatttctgc tagaggtaat cttaaatctc
     2161 caacattgaa tcccaataaa ttcattgcag tcttaactgg tataggattt acttctataa
     2221 ataaagctgc gattagagca tccataccaa gttgtaattt tctagaacct tcaatatcgc
     2281 cttcaaagaa tttagctacc aaatcgtgag tttcttgagg gcaaacatta gcaagtactg
     2341 atataactcc ttgacctcct aaagataata aaggaagtat agtatcatca ttaccagagt
     2401 agatagcaaa gtcatctgga actaaactag ctatttctgc aacctgtcct aggtctccac
     2461 tagcttcttt tacagcaact atgttatcaa ttttagcaag ttcaactata aggctaggac
     2521 ttatatttac acaagttctt ccagggacat tgtaaagtat aattggaagt ttaacactgt
     2581 tagctattgt ttcaaaatga cgcttaagtc cagctttatt agctttattg taataaggtg
     2641 ttattattaa tagagcatct actcctaatt tttcagcttc ttgacttaag ttaactgagt
     2701 gcatagtatc attagaacca cttccagcta taacaggaac tcttttatta actttttcaa
     2761 caacatactt aatagtagca agttgttctt catcagtcat agtattagct tcaccagtag
     2821 taccacaaga tactatagca tcagtaccat tagctatttg gtattcaact aattcaccta
     2881 atttgtcaaa atcaactttg ttatcctttg taaatggtgt aactagagca acagcagaac
     2941 ctttaaatat catataaaat caatcccctc ttttttattt ttgtgtttta tattacagtt
     3001 acttctaatg cttgtttttg agttactatt aatattttac aaaattatat atttatacaa
     3061 gtttgtatat tatactaaat cgtatgataa agccatttca gctatttgaa ttgcgttagt
     3121 tgcagcacct tttcttatat tatcagcaac aacccaaaga tttacaccat tatcaacact
     3181 aaaatctctt cttattcttc caacaaatac ttcatctcta tcatcaaatt ctacagcagt
     3241 tggatattcg tttttagcag gattatcaac tactacaaca cctggagctt cttcaagtgt
     3301 ttttactaaa tcatctaact caaatggatt gttaaactca acatttatag attcactatg
     3361 accatttttt actggaactc ttacagtagt tgcagttatt tttaaatcgt agttatcaag
     3421 tattttcata gtttcattta ccattttcat ttcttcttta gtgtatccat tttcagtgaa
     3481 tgaatctata tgaggaagac agttgtaaga gatttgatga gggtagaatc cagtaggatt
     3541 accgttcatt cctttctcta aatcttcaac acctttaaca ccagaaccag atacagcttg
     3601 gtaagtagag taaacaactc tcttaatttt gtatttatca tcaagagctt taaggggaac
     3661 catagcttgt atagtagagc agttaggatt agctattata cccttatgat tttttatggc
     3721 ttctggatta acctcaggaa ctactaaagg cacatctgga ttcattctcc attgactaga
     3781 gttatctact actaagattc catttgaagc agctattgga gcatactttt cactaatact
     3841 tccaccagca gagaataatg ctatttgtat gcctctatca gtaaatgaag tttcctttaa
     3901 ttcttctact atatattctt taccacaaaa cattacttta gaaccagctg atttagaaga
     3961 agagaataaa aatagatttt ctattggaaa atttctttct tctaatactt ttaaaaatgt
     4021 tctacctacc attccagtag caccaactat tgctacattt acttttttca tataaattca
     4081 ccccaatttt aaattattaa aacattattt tattttagtt atacaagtaa gatatgttaa
     4141 tatttttata tatccaaaaa ctttaatatt atattaacaa ctttaattat atacaaaaaa
     4201 cgtacaaagg tatactttgt acgtctaatt tatcactcaa agtaaaccct gtagctcatc
     4261 acctacaaaa ataagtgaca gtattacaca tgttatgtgc aatcccagaa aatattattg
     4321 caagaaatat tttcttcggc tgtaaatcct ttttccaatc attaacacct gccagctact
     4381 attggatact cttagttaca gctacctcta ccctaggtta ataggatatt aaaatttgat
     4441 tattctaata ataatacata tttaagaaaa aatcaactta tttatataaa tattgctaaa
     4501 atttaaatcc aaaatttgtc aattcttgtt ttaacacatt aagattagtt tcttccattt
     4561 cagctagagg aagtcttaaa tcaccaacat taaaacctaa aatgttcatg gcagttttaa
     4621 caggaactgg atttacttct ataaataagg cagcaattaa agcatccata tcaagttgta
     4681 atttttttga gccttcaata tcaccttcaa agaatttagt tactaaatca tgtgtttctt
     4741 taggacatat gttagcaagt acagagataa caccacttcc acctaatgat aatagtggta
     4801 gtatagtatc atcattaccg gagtatatag caaagtcttt aggtactaat ttagctattt
     4861 ctgcaacttg agctaagtct ccacttgctt ccttcacagc aactatatta tctattttag
     4921 caagttcggc cacaacagat ggctttatat tcactttagt tcttcctggt acgttgtata
     4981 aaataattgg caacttaacg ctatttgcta ttgtttcaaa gtgaagttta agacctttct
     5041 cattagtctt attatagtaa ggagttatta ttaaaagacc atccacccct aatttttcag
     5101 cttcttgact catatgaaca gacaacatag tattgtttga accagtacct gctataacag
     5161 gtattctctt attaactttt tcaactgtat attttattac agcaaaaatt tcagattcac
     5221 tcatagtagt cgcctcacct gttgttccac aaacaactag tgcatctgtg ccattctcaa
     5281 tgtgatattc gattaattca cctaattttt caaagttgac attattatcc tctgtaaatg
     5341 gggtaactaa agcaacagca gaacctttaa ataacatata atcaaatctc cttttttatc
     5401 taaatttaat tttttaagta caataataat tatagtacaa attaattaat tttaataggt
     5461 atagttaata tcttaactgt ttaaataaga tatttatatt atattaatat tagaaaaatt
     5521 ttaaataaat gttttattct caaaatatgc atattaattt aataaaatat accaaaatgg
     5581 aaataaaaaa taaattttat gagaatttaa taactaataa ttaatatatt taggttataa
     5641 taaatatgtg cgtaaaatct aacaataagc aataataccg taaatttagg aggaataata
     5701 tggatacttt aaaggaactt tttaaaatag gaagtggacc ttcaagttct catactatgg
     5761 gaccacaaag agcagcagag agatttaaga atgaaaaccc agatgcagaa agttttagag
     5821 caatattata tggtagtttg gcagccacag ggaaaggtca tttaactgac tatataattg
     5881 aaaaaactat agcacctaaa aaagtcgaaa ttgtttggga agaagatatt ataaaagatt
     5941 ttcacccaaa tgggatgaag tttgaagctt tagataaaga taaaaatgta acagctgaat
     6001 ggactgtata ttctgtaggt ggagggacta tagcagaaga aggtcaaaga aacagtaaaa
     6061 gcaatagtat atatcactta gatactatgg atgagatagt aaaatggtgc aaagaaaata
     6121 ataagacttt ggtagatttt gtgttggaat gtgaaccaaa agacataaaa gattatataa
     6181 aaactataaa agatgctatg agaaaatcta ttgatgatgg actaagtaca gatgaaataa
     6241 taccaggcaa gttattatta aaaagaagag caagtacatt ttataatgca tataaaaaag
     6301 ataagagctt ctcaacactt gtatatgcat atgcactagc agcttcagag caaaacgctt
     6361 ctggtaatat aatagttaca gcaccaactt gtggttctgc tggagtaata ccaggaatat
     6421 tctttgcaat gcaggatttc tataattatg atgacgaaaa aataattgaa gcactacttg
     6481 tagctggaat aataggtaat ataataaaaa ctaacgcttc aatatctgga gcagaggtag
     6541 ggtgtcaagg tgaagttgga gccgcttgtt ctatggcagc agcagcagta gcatacttaa
     6601 aaggtggaac tatagaccat attgaatatg cggcagaaat agcacttgaa catcatttag
     6661 gaatgacttg tgaccctgta tatggatatg ttcaaattcc atgtatagaa agaaatgcaa
     6721 tggcagctca aagagcttat gatgcagcta attatgcatt attaactgat ggctcacatt
     6781 ctgtctcctt agaccaagtt gttgaaacaa tgaaagaaac tggtatagat atgatggata
     6841 agtacaaaga aacagctaag ggtggacttg ctaaacattt cttctcttgc taaaaataaa
     6901 attttccaat aataattcct ctgttttgat ttatgaaaca ggggaattat tattaatggt
     6961 gaattattta ataatgcaaa atatttttat attcaattta gctttttatt tttaattagt
     7021 ataacatgct atataatatt ttaattataa agaaatatag aaatattttt taataaatta
     7081 gaaattggag gagattacat gagagaggca tcatatttac aagaacaact ttataaacat
     7141 aggaagtcat taaatcctat tgcagagatt gggagaaaag agtataagac ttcaaaatat
     7201 ataagagatt atcttgataa attaggaatt gagtatgaag tttatttaga aacaggtata
     7261 gtaggtgtaa tagaaggtaa aagacctaaa aaagatattg cttttagagc tgacatagat
     7321 ggtcttcata gtgaagaagg ggtaaaacat ttatgtggtc atgatggaca tgctactata
     7381 ttacttggat taattgagta tttaaatgat aataaagaag acttaaatga taatatagta
     7441 tttatattcc aaccagcaga agaaggtcct gggggagcaa aagctttaat agatgaagga
     7501 gtgcttagaa aatacaatat tgatgaaata tatgggcttc atatatatcc agagttacca
     7561 gaaggttatg taggtacaag agagggctat tttatggctc aaataggaga cattgacata
     7621 gaaatagtgt ctaaaagtgg acatggggct atgccacaaa atggtattga tggtatagtg
     7681 atagcttcaa actttgtaag ctcacttcaa actatagtgt ctagaaatat aagcccaata
     7741 gacaatgcag tgttgactat tggtagaatt gaagggggag ctagaagaaa tataatagct
     7801 gaaaatataa agatggaagg tactatgaga tgtttcagcc cagaagtgta tgagaaaatg
     7861 aagcttagag ttagagaact tgctagaggg tttgaattgg cttataactg taaggttaat
     7921 ataaatatta tagatgatta tattgctgtt aaaaatgaca aggatttgta tcaagagttt
     7981 gtagaggcta ttggaagtga tactgttgta gagttagagc cacttatgat atcagaagat
     8041 ttttcttatt atcaaaaaga agttccagga ttatttttta tgttgggttc aagaaacgaa
     8101 gaaaaaggat ttgtaaatgg tcttcataat ataaacttta attttgatga aaagatatgt
     8161 gtaaatgcat tgaatgttta ttcaaaatta ttaaaataca aagaagcaat agattaggaa
     8221 gataagttat aaagattaaa aagcataaat acctaaattt aaaaaaagtg tattaataaa
     8281 taccccttac atatttgtat aaatttattt taattgacaa aaatacaaat aagaaggggt
     8341 gatttttttg aaagaaaaag tacaaagaga aaagaagata actaatggca agaatactaa
     8401 aatattgaca aatgatgata taatgaaata tgagatagcc tcagaactag gtcttatgga
     8461 taaagttggt gaacgtggat gggcaggact tacagctaag gaagcaggaa gaattggagg
     8521 tatgcttaca tcacgcaaaa agaggcttaa aaagattgtg gaggagcaga ataaaaagga
     8581 tgagtcaata tagtgatttt gcgtttgtat atgatgaact tatgaatgaa gttgattata
     8641 atggttgggt taaatatata gaagatataa tagatagtga aggtgtaaaa gtaaaaaata
     8701 tattggaatt ggcatgtggc acgggtaatc ttacaattcc attgactaaa aaaaattacg
     8761 atatagctgg tatagatata tctgatgaga tgcttagtgt agcaagagaa aagtcagaaa
     8821 aagaaggagt agaattagtt ttacttcaac aagatatatc agagcttgat tttgaaatat
     8881 ctgatttgga ctgtgtactt tgtgcttgtg atggattcaa ttatataact tatgatgatg
     8941 atttggaaaa tgtattttca aagacatatg aattattaaa gaaagatgga atattcatat
     9001 ttgatataag ttctttttat aaattagcca acatattggg aaataacatg tatggagaaa
     9061 atagagaaga tatagcgtat atgtggcaaa attactttga tgaagaagag aatctaattg
     9121 aaatggaact tacattcttt attaaagatg aatgtggaaa atttgaaaga tttgaagaga
     9181 tacaccaaca aagagcatat actgaagatg agatagttga tatgcttgaa aaatctggat
     9241 ttaaggatat aaaatattat ggggatttta catttgacaa acctagtgaa gaaagtcaaa
     9301 gaatcttctt tgtatgtaaa aaataagata tttttgacta tataagataa ttattaaaaa
     9361 taaccatgat ataaaaatat agaaaatgca gttttataga ttaaaagtaa agtgatgata
     9421 ctttatgact tttatttttt aataattata aagttctata gataaaaatt aaaatataat
     9481 aactattgct tagtaaaatt aaaataaaat gggttttgcc caaggttaag atagacaagt
     9541 atttatagat taaaattaag gtagtaatat aataaaaata agacaattaa cgggacatgg
     9601 aggaatatta atgagagatt atgtactaag agcgacatca ggaaatggtc aagttagagc
     9661 atttgtcgca actactagaa atacagtaga agaagctaga agattacatg aaactacaaa
     9721 agtagcaaca gcagcacttg gaagaacatt aacagccaca tctataatgg gattaatgat
     9781 gaaaaatgat agtgataaat tgactgtaat aataaaaggt ggaggtccaa ttggaactat
     9841 tatcgccaca tcagactcta agggaatggt aaaaggatat gtaggaaatc cacaagtaga
     9901 ggttgaagac tatccaaatg gaaagttaaa tgtagcagca gcagtaggta cagaaggtgt
     9961 tgtaaaagtt ataaaagact taggtcttag agaaccatat aatgggactt atccattggt
    10021 aagtggagaa attgcagaag actttactta ttattttgct gtatcagagc agactccatc
    10081 agtagtagct ttaggtgttc ttacaaaaga agatgaagta gagtttgctg gaggatttat
    10141 agttcaatta atgccagatg cagaagaaga gactattgct aagttagagg aaaatgtagc
    10201 taaattacct tctataacta acatgttaaa agaaggaaaa tcaccagagg atatattaaa
    10261 tattgttttg gatggtttgg aacctaaaat acttgatacc tgtgaagttg ggtttatgtg
    10321 tgaatgttca aaagaaagag taaaaactgc tttggttgca attggtaaaa aatcattggc
    10381 tcaaataata gaagaagata aaaaagcaga agttggttgc cagttctgta ataagaagta
    10441 tatgtatagt gaagaagagt tgcttgaaat tttaaaggaa atgtagacta taaaaatagt
    10501 tgtattgata taagtaatgt tatagtaata tagtaaagtc gtattgatat agtaattaaa
    10561 gtataattta ttaataatag acatatttat attaaaaaat aagtttaata aatttttaag
    10621 cttaataaat tttaagaatt aagaagcttt ctggctgtaa tgtttgcaat gttgcagtta
    10681 gaaggctttt ttattttatt atagttcgtg tcaaagattg tatgaaacaa taaaatattg
    10741 taaaataatt tgtatattta gacctgattg acacaaaggt ttataagata tttgagttga
    10801 ttatacgaaa ttctatgaag tagtaaccct gtgactttaa tcatgggagg ttcagaagaa
    10861 ggagaaaatt ttaaatatgg aaagtaaaac gaagtacata ggaataagta tattaatatt
    10921 attgatgata tttttaattg caaagaattt taacggaaaa cttgaaatac ctattcctga
    10981 gagtaatagt agaaaattta aatcagcagc agtgttttat cctcaacatc aagatgatga
    11041 ggttttatgg ggaggaagtg ccattgtaga tgctataaaa cagtgtggtg ttgataatgt
    11101 atatgtggta ttagtatcag atggttctgg agttaacgtt ttcaaagcta acacaaaatt
    11161 tagaaattta actaggaagc aaaaggaaga acttagaaat aacgagttta aatcagcttt
    11221 gagagagctt ggagtgaaac ctcaaaatgt gattatactt gcagatatag ataaaaagga
    11281 aggcacacat tatgaattaa tggaaaagac tatattggat tttgaacata agtttaaagg
    11341 caatgtgacc catatagccc atcactataa gtatgatgac catataatgc atagaaagaa
    11401 tggggaagtt ttaaagaaac ttaaacgtga aggtaagata aaagatgact tgtattttgt
    11461 taagccaaaa tatgtaaagt atataccaag aaatgaaaga gctatctata aagcaatgga
    11521 ttttgatgac tacaataagg ttaagagtgc ttgttatgaa tataaggttg taaattcaaa
    11581 gcgtaaaatg tatggtatag gatatatttc ggcacatagt tattttgaac atcttctaaa
    11641 tgaccctgaa cttacgtctg tattaagtga agattaattt cttataagta gtaagttatg
    11701 tttgataagt tgattggaat tttctatagt tttgaaggta ttggaaattt agttttattt
    11761 aaagatttaa agatagaggt ttttagtgtt taaaatttta aagttaagtt gaataattgt
    11821 atagaattat ttgtgaaaga agaaacagtg taaaacatag tatcttattt atggttttaa
    11881 aatcataggc aagatacttt ttttatgtaa ctaataccat tttgagatta ttaacttaag
    11941 aattttatat aatttaacac tcatatataa tgatgatatt taggtagaat agatgtaatt
    12001 acgcttaaat aaaataactg tattttttat aaaaatccaa accctacact atactaccag
    12061 ataaaatcta catgctataa tttgacctgt gtttataaaa aaaggagtaa tctaataaaa
    12121 tagtatttca cttatgtata actaacaact attattacga ttttctctaa ataatttaaa
    12181 gaaaaataat gcaggaggta aaatatgaac aatgaattta taattttaaa aggttgcaaa
    12241 gagaacaatt tgaacaatat ttccttaaaa ataccaaaaa gaaaaataac catattcaca
    12301 ggggtgtcgg gttctggaaa gtcatctatt gtatttgaga caattgcaaa agaatcacaa
    12361 cgccaactaa atgaaaggtt tagtacattt gtaagaagtt ttttacctaa gtatggagag
    12421 gttaaagctg attgtataga aaatttgtca acaccaatta tcatagacca aagtagactt
    12481 ggtggaaatt caaggtcaac tctaggtact attacagatg taaattcctt tttaagagct
    12541 ttatattcaa ggtttggtag tgagtatata ggtaatgcca atatgttttc ttttaataat
    12601 attgatggta tgtgcccaca ctgtcatggg cttggaaaaa agctagttcc taatatgaac
    12661 caaattcttg atatgaataa atcattaaat gaaggtgcta tattgctttc agggtttgga
    12721 gtgggttctt ggcattggaa tatattcgct gaatcaggat tttttgatat taataagagg
    12781 atatgtgatt attcagaagt agaattggaa aagtttttgc atggtaaagc agaaaagatt
    12841 aagatagaaa atgctggtca aactaacatg acatatgagg gattaatggt taaatttaat
    12901 cgcctatact taagtagaga gggagaaata tctgaagcta ctaagaaaaa attgagtaaa
    12961 cttcttatag aagatagatg tcctatatgt gatggaagaa gacttaatga aagagtatat
    13021 aggtctttaa ttaatggtta taatatagca gatttaacta gtatgcaaat tgatgaattg
    13081 gctgaagtta ttaaaagtat agatgagcca gaagcacaac ctttaattaa aggaataata
    13141 gaaaagttaa acagtatcat agatataggt cttggatatt taacactaga tagagagaca
    13201 tcttctctat caggagggga atctcagcgt ataaagatgg ttaagtattt aaatagtaat
    13261 cttgttgatt taatgtatat ttttgatgaa ccaagtgtag gacttcatcc aaaagatgtg
    13321 tataaattaa ataatctttt aaaaaaattg cgtgataaag ggaatacaat tatagttgtt
    13381 gaacatgacc cagatgttat taagattgca gaccatattg tagatgtagg accaaaggca
    13441 ggtaagtatg gtggagaagt tgtgtatgaa ggcagttatg aaaatctact tacaagtggt
    13501 actttgacag ggaatgcttt aagtaaattt cttcctatta aagaaagtgt aagagaacat
    13561 agtggatatt tagaagttaa aaattgtaat aaaaacaatt taaaaaatgt atcgattaag
    13621 atacctaaag gtgtattgac tctagttact ggagtagcag gagcaggtaa aagtacgttg
    13681 attaaggatg aatttttaaa gcaaaatcct agtgctgtac ttatagacca aagccctgtt
    13741 tcagcaaatt caaggtcgag tttggcaaca tatagtggaa ttatgaacaa cataagaagc
    13801 atattttcaa aaacaaatgg cgtaaatgct tctttattca gttcaaattc agaaggagct
    13861 tgtgataact gtaagggttc tggaatagta gaaatgaatc ttgcttttat ggagagtata
    13921 aagagtacct gcaatatttg tgaaggtaaa aaatttaaaa aagaagtttt agaatatagg
    13981 tttcaaggga agaatataat tgaagttctt gaaatgtctg ttttagaggc aattgagttt
    14041 tttaatttaa aacagattaa aacgaaatta caatgtattg aaaaaatggg tattggatac
    14101 cttactttag gacaaactct tgatactttg tctggaggag agtgtcaaag attaaagctt
    14161 gctagtgaat taaataagga aagttcagtg tatatattag atgaaccaac aacaggtctt
    14221 catatggctg atattgagaa ttttataagt ataattgaag agattgtaga taatggaaat
    14281 acggtcataa taattgaaca caatatagat gtaattaaaa gagctgattg gattattgag
    14341 ctgggacctg aaggaggaac aaaaggcggg agagtaatat ttgaaggtat tccaaaacaa
    14401 ttatgtaaca ataaaatatc attaacagca aaatatatag tataataaat aaaatataat
    14461 aaaattataa tgatatttta ataaatataa tgggtatata aaatgataat taaacttaac
    14521 agtaataaat aatgtgagaa atattcaaat ttaattaaat aaagtgtcag aaatttgttt
    14581 aaattttagt attttaacgg ttctgacctt ttttcttatt tttatggaga atatcgagga
    14641 tggagtctct aatagttact tttttgtgtc tacttgcaag tttgattaaa aaatggctat
    14701 acacacttgt gacttcagtc atgggaggtt cagattataa tcttaatata taatttgtga
    14761 aataatttga tgacgatttg ctgatgtata aacaataaag attaactaca ttaaaattta
    14821 aatcttgtta agtaaaactt ataaaaggag agagatggat gataaatgat attctaacct
    14881 tattatctga aagaagtgat ttttttataa agctatccat agaacatttg atgatttcta
    14941 ttatttctat aataattgcg attgttttgg gtggtataat tggtattatt gtaagtgaat
    15001 ttcataattc ttctaaacct atattgggaa ctatcaattt tctatacacc attccatcta
    15061 tttctatgct aggatttctg ataccatttt ccggaattgg aaatactact gctgttattg
    15121 cacttaccat ttatgcatta ttgccaatgg ttagaaatac atatactgga attactaatg
    15181 tggataaaaa tattcttgaa gcagctaggg gaatgggaag tacagatttt cagatattgt
    15241 ataaaataaa acttccgtta gccctacctg ttattatgtc tggtattaga aatatggtga
    15301 ttatgacaat tgcattagct ggtatcgctt catttatagg tgctggaggc ctaggtgtag
    15361 ccatatatag aggaatcacg acaaataaca caataatgac aattactgga agtatactta
    15421 ttgctctatt agctttaata tttgatttta ttttagggct ggtagaaaaa ttttttcaac
    15481 gaaaaagaaa aaagaaaaat aggaaaaaag tttttgccat tctaggaagc cttattctta
    15541 tagtaattat ctttacgtct tatttattta atccttcaaa gactcaaact attcatattg
    15601 ctactaaacc tatgactgaa caatatattc ttggtgagat gttggatatt ttaattgaaa
    15661 aaaacacagg tctaaacgtg gaaattacac aaggtgtagg agggggaaca tctaatatcc
    15721 agccagctat ggagaatgga gaatttgaca tttatccaga gtatacaggt acaggctgga
    15781 atatggtact taagaaaaat gaattatata ctgaaagtat gtttagtaaa ctacagtcgg
    15841 aatacaaaac taaacttaaa atgcaatgga ctggtatgta tggtttttct aatagctatg
    15901 cattagcagt tagaaaagaa gttgcagata aatacaattt aaaaaatata acggacttaa
    15961 aagatgtatc ttctaaattg acatttggag ctgaatatga cttttatgag agagaggatg
    16021 gatatactcc attgtgtaat acatatggac tgaactttaa agatacagtt gatttagata
    16081 ttggattaaa ataccaagct atcaatgaag gtaagattga cgtaatgcct atatttacaa
    16141 ctgatggtca gtatagtgtt tcagatgttg tagttctaaa agatgataaa aatttctacc
    16201 catcttatca atgtggaaat gttgttcgtt tggaagtatt agaggaaaat ccagaactat
    16261 caaaggtatt taagatggtt ggagatattt tgactgataa agaaatggct aaaatgaatt
    16321 atgacgtaga aaacaacaat ttagaaccta gagaagttgc tcgtgagttt ctgaataaga
    16381 aaggtctttt ataaattgga ggaaatataa tgacacctat tatacaattt aaaaatatta
    16441 aaaaacaata taatgataaa actataatag ataatcttaa tttagatata gaaaaaggag
    16501 agtttttgac tgtaattggt tcgtctggtt ctggtaagac aacactctta aaaatgatta
    16561 atggtctgat tttgccagat ggaggaaata ttttgataaa ccaaacagat atcaaaaacg
    16621 aggacttaat taaattaaga agaagaatag gatattgtgt acagggaagt gttctttttc
    16681 ctcatatgac tgttgaagaa aatatttcat atgtaccaaa tctcctaagt aaaaagaata
    16741 aattagaagt aaaaagtgct gtaaacaagt ggatggaaat agtgggattg ccaaatgata
    16801 tgaaagtgcg ttacccatca gaattgtcag gtggtcagca acaacgtgta gggattgcaa
    16861 gagctttagc ttcttctcca gaaattttat taatggatga accttttggt gcagttgatg
    16921 agattacacg aaagcaatta caaaaagaga taaaagaaat tcataaaaaa acaggagtta
    16981 cgattatctt tattacgcat gatatttatg aagctttgat tttgggaaca aagactttgg
    17041 tattaaatca tggagttgtt caacagtatg atactcctga gaatatttta aatactcctg
    17101 ctaaccaatt tgtagaccag ttattgaata taagaaaatc tataatagat gatgataatt
    17161 taaaagaata aatttaaatt taaaatcaaa ttgttgtgat aaaaactatt gatttagagc
    17221 taacttcaag ttgtatactt gaagtggaaa agttagatta aggtatagaa gggcatttag
    17281 cagttggctg tagacgaggt aactgctgaa ggtgctttca ataaatggct agaacctgta
    17341 tctgttgaag attataataa attgaaataa gaagctcaat atacagagta gataggcact
    17401 tcaaatagaa gtgtcttttg tgtgccataa aataaatcaa aatattagca aagaatgtga
    17461 aaaacaaaat aaaataatat gctatcttta aaataggagg gatgctatat ggataacaat
    17521 ttgattacca ttgaaaaaac tttagattat atagaaaaac atcttttaga tgagatgtta
    17581 gatttaaatg taatttctaa agagataggc tattcaaaat accatttaca tagaatgttt
    17641 acatcagttg tcggatttag tgtacataat tatatacaaa gacgtagact tactgaagca
    17701 gcgagaatgc taatttttac agaaaaacca attattgaga ttgctttaat ctcggggtat
    17761 gatacacaac gctctttttc aagagggttt aaaaaaatgt ttaaacgtag tcctaatttt
    17821 tttagaagac atcaagattt tttaccacta caattaaaat ttgatattca taatagaaaa
    17881 aaattacgtg gagatatggt tttagatgtt aaaaaagtta attgtgcaga tataaatatt
    17941 gttggctatt ctggtaaagt aagaaaagga tttcatatta ttggaaaatg ctggagggat
    18001 ttgcataaaa ataaagagat gatagaaaat aaggtagatt taggtttttt aattggagtt
    18061 agtgattata gcaattttaa agagattgag aatactccta catttacata cattgcaggt
    18121 gctcaagtag ctacttttgg caaattacct aatggaatgg aaaaattcgt attaccgaaa
    18181 agtaattata ttgtttttac ttttattggg aaaaatgagg atagtatgca aaatgttgta
    18241 gaatatatct atcaagaatg gttccctaat tcaagttgcc agtttaatga aaataattta
    18301 tatgactttg taaaatatgg agaaaaaact gatgagaatg gtttgagtga aattcagttt
    18361 tgggttccaa tcatttaaaa gaaggtatta tgtataaagt agatggattt atataggcaa
    18421 agttttacag cagtatgtat ttataaataa tttatagttt gtaggaaaga aataatttta
    18481 ctataagatt atgataaaat acacaatact atgacaaaat agtgttaaat aatagattta
    18541 attttgcata ggaaaagttc tataatggtg tgtattcata aataatttat aatctgtagg
    18601 aaagaaatag ttttactata agattatgat aaaatacaca atactatgat aaaatagtac
    18661 taaataatag atttaatttt gcaaaggata aggtgtttta ataaaaatga atgtagaaaa
    18721 cgaattactt aaaaacctag atagattgca tacaacagag ttaggcgttg taagaattaa
    18781 gaaaaatctt tctttggaga caaatgatgt agtgaactgg tgtaaaacta aaatagaatc
    18841 tccaaatgcc attattaata gaaagggaaa aaactggtat ataagtgtat atgattgtat
    18901 tataacagta aacgctcaca gttatacaat tattacagct cataaagaaa agaaatgaat
    18961 tgcaaaatac aaaggtcaaa agcattttcc actgtttgta gtacctatga agaagtatat
    19021 aaaataatat tacttttgaa taataattta aattttggag gttgaaaaaa tgaatgatac
    19081 tgtaaaagaa aaattggcag agtcactaac ttctgatact actgatattt taccttattt
    19141 gccttattta ttacaagatt tttgggaatt aggaagttca ccagaacaaa tgttacaatt
    19201 atttagaaag catatacctt ttaatgagga tacaaaagtt ttggatttag cttgtggaaa
    19261 aggtgctgta tctgtgaagc ttgcaaaaga gttgaatata catatcaaag gtattgattt
    19321 gatacctgaa tttattgatt atgctagaag aaaggctatt gaatataagg ttgatgcttt
    19381 gtgtgatttt gaaatgaatg atgctaatag ttctgtaaaa attgagcatg attatgattg
    19441 tgtgattttt ggagctgtag gggatatttt aggtaattat aaagaaacta taagtaagct
    19501 attacctaca ataaaaagta aggggttcat tttaattgat gatgcatatg tagtagataa
    19561 atctacaaat gaacagctta attttgagag ggtgtatccc acttacaatg agtggtgtat
    19621 attgttcaaa gaattaggtc tgaagctaat tgaatgtata ccatgtttag aacttgaaaa
    19681 tgatgttgaa gaggaaatga attggattat aactcgtgca aatgagctaa ttaaaaaata
    19741 tccttctcaa aaagatatgt ttgaacaata tgttattagc caaaaaaatg aatatactga
    19801 tttacagcag gaccttgttg gagcaacttg gattttacaa aaagaataag ataaatatta
    19861 gactagataa tcaatgttat agtgaattat cccatgtcta gtgaatataa ataacataaa
    19921 aaaccgtcaa gatgaatagt ttattcgtgc ttgacggttt ttagtatttg ttgaagtaaa
    19981 attttatttc tttagtatat cacttttagt caatccattt gatttagctt gagtattcca
    20041 ttgatgattc cccataagtt tatataggaa tctagggaag ttaggtgaaa taaaaatagt
    20101 acttttgttg gaatcatcta tatgtatatt atcactaagt atattttttg aaagttcttt
    20161 taatgcaatt cctaaatctt ttttaggtcc tttacccaaa ggtacggatt ctagtgaacc
    20221 aaacatctcc ccagctccaa ttccaatacc ttgaacccat gtaaagttga tttttttaca
    20281 ccaatgctct atcatttgaa ttgccaaatg attatgttca ccttcattga atccacagtt
    20341 aactattgca tacactggaa taggtttttt attttgtgtt tttaaaaatt tttcacattt
    20401 ctctaaaaaa tgaagtaaat gagatggaat accatctaca taaagaggag atgcgattat
    20461 taatctatca caattaagta tggcattaag agcgtcagga tacttagatg tgctatctac
    20521 tttaaatgta aaaactttat tatcattttg aataagttgt tttaattcag ataaaaaata
    20581 ctgtgaatta tttttattta cttttggact accatttatc attactatat tcatatggat
    20641 tcacctctta tatcttgtat attttcatag aaacaaacag agtgttcttt tatattgaaa
    20701 tttatagcat ttccatttac taatttcgta gcagtttctt tttcagcttc tgtaatacaa
    20761 tctccataga atatagcttt taaatttatc tgtttatcat atctgctttt atgacgcatc
    20821 atattatctt ttattacaaa gtatggaaga atataattaa tgcttttatc aagtacgttt
    20881 ttgacaaaag ggctaaaccc tccgtaacag catctgctta ttataataat tccatcagag
    20941 tcatttataa gtttacccat gttgctgtaa taatctttta caacacattc agaaggagtt
    21001 ttaatccagc aaccaaaaca accaatacat ttgtggattt cttttgtgtt tggaagtatt
    21061 tttatattgt catcaagttt gggtaataac ttttctaatt ctttgtcagt taaatcatgt
    21121 attaaaagcc tcataaagtc catctccttt tattatgtat gtttacttct aaaaattata
    21181 tcttatagat ttttcagtaa atctttacac caattaataa caaaattata atagtcaact
    21241 ccataaatca ttgttgcata catatatgta tattggtcaa cacaatgatt ttcttctgca
    21301 tcattttttt gtttacttaa tttatttaga agtaattcta cttcagttat taacattttt
    21361 aagtttgttt caattatttc tttgggtaga tacttgtaaa agaatatatt aacaaggtgg
    21421 tcttgctttg ttttagaaaa atttataggt ttctttaacc attcaagaaa tacttcttta
    21481 ccagtattag ttatggaata tagttttttt aatttgctac catctataac ttcgtgatag
    21541 tgtatatatc cttttgtttc taatctttta agtgcaggat agatacttcc aaagctggcg
    21601 tcaaaaaagt acgaggtact ttctgacatt atttgtttta agtcgtatcc acttaattct
    21661 ttttccatta aaaatcctaa aataatgtat tctaacatat tacctcctgg tatcaattag
    21721 atatatatcg attcgatata tttattatta cagataataa atcttacgtc aagatgcttt
    21781 ttaaaataag ctaaaaagaa ttaggagtta ttgataaata tgcaaaaaaa ttaatataaa
    21841 aggtaattaa atatcaatga agatttaaaa atagttaaat caaagtaaga gtctaatata
    21901 taaaatttat agtaacttta tggtttaaat ataaacttgt gtgctattga caaagtataa
    21961 aattagcagt aaaataattg catgagcaaa tagattgttg cgaacgcaaa aaaataaaga
    22021 caataaatat taaaggagag aatatgagag agctattaaa atgggtttcc attataaata
    22081 gatacaatac aaattatatt gacaggaaat tggcggatat tggaatcaat aatagccaat
    22141 atttttatgt attacacata tgtaataatc caggtattac acaggacact atatttgaga
    22201 aaattcttgt gaatcctagt aatataacaa gagctttggc aaatttagaa aaagaaggct
    22261 ttataacaag agaaccaggt gtaaaggata aaagaacatg gcatttatat cctacagaaa
    22321 aatctttaga atgttatgat gaaatactaa aaataacaaa tgggtatgtt gaggagttgt
    22381 tgagttcatt tgagaaagaa gagcaagagt tgtttatgtc aatgttaaag aaagttgcat
    22441 ttttggctat tgatatgaat gaagaagcaa aattggaggc gaaggaaaat ggaagaaaaa
    22501 tataaggagc cattggaata tgaaaaggtt tcaaagttat taactaagta cgcaattcct
    22561 agtattatag caatgttagt aagtgcttta tataacattg ttgaccaaat atttattggg
    22621 caaggtgttg gtgtattggg taatgctgct acaaatgtca cttttccact aacaacaata
    22681 tgtactgcaa ttgcattatt gttaggaatt ggaggagcgt ctaagtgttc attggaatta
    22741 ggtgctaaaa attcagaaaa agctacaaaa gcagcaggaa attctatatg cttgatggct
    22801 gtttttggaa taagtttatt tatagtagta tcaatatttt taacaccact attaaaattc
    22861 tttggctcta catcagaaat actaccttat gcacacacat atacaaaaat tacatcaatt
    22921 ggattaccat ttcttataat gtccactgga atgagtaagt tgatacttgc agatgggaga
    22981 ccgaaagctt ctatgttttg tatgttaata ggagcagtta ttaatacaat tttgaatcca
    23041 ttattcattt ttgtttttaa tatgggaatt gctgggtctg ctttagcaac tgttattggg
    23101 caacttatat cttttggaat aagtgttcat tatataaaga attttcaaca tattaaatta
    23161 cataagaaaa gttttaaatt agatagtata atttataaac atatatttgc gctaggttca
    23221 agctcatgtt ttaatcaatt agcaatgact gtaacacaga tagttatgaa taatacattg
    23281 gcatattatg gggctaggtc agtttatgga agtgagattc cacttgcttg tgtcggtatc
    23341 attattaaag taaatatgat ttttatatct ataattattg gtatatcaca aggtatgcaa
    23401 ccaattatag ggtataatta tggggctgaa aagtataatc gtgtaaaaga agcatataag
    23461 tttgcagtgg gaagtgcaac tattatatct gttattgcat tcttatgttt ccaattcttc
    23521 ccaagacaaa ttacgtctat atttggtaac ggaaatgaga cttattttat atttgcagaa
    23581 cattatttta gaactttctt gttcttaaca tttataaatg gtgttcaaat agtatcatca
    23641 actttcttta catcaattgg gaaatcagtg ttgggacttt ttacttcttt gactcgtcaa
    23701 attttatttt taattccatt gatagtaatt ttaccaatgt ttatgggaat tgatggagta
    23761 atgtttgcag gaccaatagc agatgcagca gcggcaatgg tatgtatata ctttgcagtt
    23821 catgaaatga aatcattgac tataaagcaa aataatttga tgagtaacca taataagatt
    23881 gcagaggtat aagacaatat ttaagaagta tagaaaatta atttaaaaaa tataataaat
    23941 taatttagga agtgtagaaa attaat
//
LOCUS       DAEPUT010000061        23586 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.063, whole genome shotgun sequence.
ACCESSION   DAEPUT010000061 DAEPUT010000000
VERSION     DAEPUT010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23586
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.063"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            403..3057
                     /gene="adhE"
                     /locus_tag="KRL22_002603"
                     /gene_synonym="adhC"
     CDS             403..3057
                     /gene="adhE"
                     /locus_tag="KRL22_002603"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH1273076.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYANGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            3333..5552
                     /locus_tag="KRL22_002604"
     CDS             3333..5552
                     /locus_tag="KRL22_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1273077.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNNGTIILHPQGDSLSKNIYKLLKQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFIAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFALVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            5806..6468
                     /locus_tag="KRL22_002605"
     CDS             5806..6468
                     /locus_tag="KRL22_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBH1273078.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            6839..8248
                     /locus_tag="KRL22_002606"
     CDS             6839..8248
                     /locus_tag="KRL22_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBH1273079.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLASSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            8363..8638
                     /locus_tag="KRL22_002607"
     CDS             8363..8638
                     /locus_tag="KRL22_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HBH1273080.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            9268..9579
                     /locus_tag="KRL22_002608"
     CDS             9268..9579
                     /locus_tag="KRL22_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273081.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            9581..11506
                     /locus_tag="KRL22_002609"
     CDS             9581..11506
                     /locus_tag="KRL22_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBH1273082.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPIENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            11509..12000
                     /locus_tag="KRL22_002610"
     CDS             11509..12000
                     /locus_tag="KRL22_002610"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBH1273083.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            12051..12614
                     /locus_tag="KRL22_002611"
     CDS             12051..12614
                     /locus_tag="KRL22_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HBH1273084.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            12629..13606
                     /locus_tag="KRL22_002612"
     CDS             12629..13606
                     /locus_tag="KRL22_002612"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HBH1273085.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            13593..13916
                     /locus_tag="KRL22_002613"
     CDS             13593..13916
                     /locus_tag="KRL22_002613"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBH1273086.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            14033..15811
                     /locus_tag="KRL22_002614"
     CDS             14033..15811
                     /locus_tag="KRL22_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBH1273087.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            15808..17181
                     /locus_tag="KRL22_002615"
     CDS             15808..17181
                     /locus_tag="KRL22_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBH1273088.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            17187..17855
                     /locus_tag="KRL22_002616"
     CDS             17187..17855
                     /locus_tag="KRL22_002616"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBH1273089.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            18133..19182
                     /locus_tag="KRL22_002617"
     CDS             18133..19182
                     /locus_tag="KRL22_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1273090.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(19417..20775)
                     /locus_tag="KRL22_002618"
     CDS             complement(19417..20775)
                     /locus_tag="KRL22_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1273091.1"
                     /translation="MLRVALYIRVSTEEQALNGDSIRTQIEALEQYSKENDFNIVGKY
                     IDEGCSATNLKRPNLQRLLRDVEKDKVDLVLMTKIDRLSRGVKNYYKIMETLEKHKCD
                     WKTILENYDSSTAAGRLHINIMLSVAENEAAQTSERIKFVFQDKLRRKEVISGTIPIG
                     YKIENKHLVIDKEKKYIVKAIFDEYEKSGSVRTLIETINNLHGELYSYNKIKNILRNE
                     LYIGIYNKRGFYVEDYCEPIISKKQFKQIQRILEKNKKTTPNKNIHYHIFSGLLKCKE
                     CGYTLKGNSSNVGEKLYLSYRCSTFYLNKNCVHNVTHNEKHIENYLLTNLKPQLHKHM
                     VKLEAQNEKIRRNKKSNKKDEKKKIMKKLDKIKDLYLEDLIDKETYRKDYEKLQSQLD
                     NITEEQESQIIDTSHIKKFLDIDINEMYSDLSRVERRRFWLSIIDYIEIDNNKNITIN
                     FI"
     gene            complement(20840..21313)
                     /locus_tag="KRL22_002619"
     CDS             complement(20840..21313)
                     /locus_tag="KRL22_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBH1273092.1"
                     /translation="MNSYEKLLSEADDNNIIVREVPLISNSHGLYKNNRIALNKNTLN
                     NISEKACVLAEELGHHYTSYGNILDLNKVENSKQEYKARLMAYNKLIGLKGIIDSFNA
                     GCKTITEMAEYLDVTEKFLNEALECYKSKYGFSATLDNYVIFFEPRFSIMNANFL"
     gene            complement(21331..21786)
                     /locus_tag="KRL22_002620"
     CDS             complement(21331..21786)
                     /locus_tag="KRL22_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273093.1"
                     /translation="MNTENDLKMLEITNRIKNKRLELNMSYQDLANKTGLSKSTLQRY
                     ETGAIKNIPLDKLEILAHALDESPAFIMGWNEDCKQIKIKENKLLSSFNALNDIGQNE
                     AIKRVDELTQIGKYVNKNHIDTIAAHNEHLHEEGEIEKIYQDLDDMDNW"
     gene            21940..22161
                     /locus_tag="KRL22_002621"
     CDS             21940..22161
                     /locus_tag="KRL22_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273094.1"
                     /translation="MNISKLKGKMVEKKYTQKKLAEELGMTVQALNAKLNNRSQFKIE
                     EAVKISNILQIEEPGEIFFDNYIPKMQRN"
     gene            22209..22412
                     /locus_tag="KRL22_002622"
                     /pseudo
     CDS             22209..22412
                     /locus_tag="KRL22_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
     gene            complement(22553..22726)
                     /locus_tag="KRL22_002623"
     CDS             complement(22553..22726)
                     /locus_tag="KRL22_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008720698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273095.1"
                     /translation="MATQKPRFTITVDDELLKEIDDFRFDKRFSTRTQATIELIKLGL
                     EKLNAEKCKETKE"
     gene            22882..23052
                     /locus_tag="KRL22_002624"
     CDS             22882..23052
                     /locus_tag="KRL22_002624"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273096.1"
                     /translation="MPTKSKRISITIFPELETDLDVLKKEKFYKESQSEMLRYLIKLG
                     LQVNKEKVYKNE"
     gene            23069..>23586
                     /locus_tag="KRL22_002625"
     CDS             23069..>23586
                     /locus_tag="KRL22_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HBH1273097.1"
                     /translation="MNDLTIIKQNNQFLVESREVAELIEKKHDNLLRDIRGYKKILED
                     SSNLRSQDFFIESTYINTQNKIQPCYLLTKKGCDMVANKMTGEKGIIFTAIYVTKFEE
                     MERELKEQQPKLPTTYKEALQQLLIEVEEKEQLQLENQEKDKVIQLQQPKVLFADSVA
                     SSDNSILVGELA"
BASE COUNT         8981 a         2856 c         4190 g         7559 t
ORIGIN      
        1 actatatgtt gtaaatgttt gtacatttaa ctatatttac tttaacttgt taattaagtt
       61 ttaattttca ttttcaagga tttttatttt taaacttgat agagtatcat attaaaaatt
      121 ctttttataa agttttattt gcaaaaaata caaaaatata aacgttaaaa aaataacgtt
      181 atccttaagt ttttagatga tttcattagt gatttgcgta aaaaataaag tgatatctag
      241 ttaaattaag tatttgtaaa gctagatatt attagtagaa atgatgttat attagataaa
      301 aaataaaatg ttaaaaaaat aacttgaaaa taggaaaagt aaatgctata atgttaataa
      361 attaacataa taaataaaaa actatctcag gaggttgtta aaatggctca taaagaacaa
      421 gtaataatag aaaataaaaa agaaaatgaa gttatgtcag ttggtttaga tactgtaaat
      481 aacgttgaaa gcttagttaa aaaactagca aaaatcagag aagctcaaaa aatatttgct
      541 acatatagtc aagagcaggt agataaaatt tttttagcag catctttggc agctaataag
      601 caaagagttc ctctagctat aatggcacaa aaagaaactg gtatgggaat tgctgaagat
      661 aaggttataa agaatcatta tgcctcagag tatatatata atgcatataa agaaactaaa
      721 acttgtggtg ttatagagaa agacgaagca tttggtatga ctaaaattgc tgaaccaata
      781 ggtgttattg cagcagttgt acctacaact aatccaactt ctactgctat ctttaaagca
      841 cttttagctt taaaaactag aaatggaata attttctctc cacatccaag agcaaaaaat
      901 tctactatag aggctgcaaa agttgttctt gaggctgctg ttttagctgg agctcctgaa
      961 ggtataatag gatggataga tgagccatct ttagaattaa ctacaactgt tatgaaagaa
     1021 gtggatttga cccttgctac aggaggtcct ggaatggtta aatcagcgta ttcatctgga
     1081 aaaccagcta ttggagttgg tgcaggtaat actccagcaa taattgatga tagtgcagat
     1141 ataaaaactg ctgtaaactc aattcttgta tctaagactt ttgacaatgg tatgatatgt
     1201 gcttctgaac aatcggttat agtattagaa aatatataca atgaagtcaa aaaagaattt
     1261 aaagagcgtg gtgcttattt attagataaa gatgaaacag aaaaaataag aaatataatt
     1321 ttagtaaatg gaggattaaa ttctaaaata gttgggcaaa cagcttgtac tatagcaaaa
     1381 cttgcaggct ttgaagtccc agtagatact aaggttttaa taggtgaagt agaatcagtt
     1441 gaaatagaag aagcttttgc tcatgagaaa ctttcaccag tacttgcaat gtacaaggca
     1501 agtgattttg atgatgcagt tagaaaagca gaaaaattag tagaagatgg tggatttggg
     1561 catacatctt cattatatat tgatgatgta aatcaaagag aaaaacttga taagtttact
     1621 tcagccatga aaacttgtag aattttaatt aatactcctt cttctcaagg tggtataggg
     1681 gacttatata attttaaact agctccttct cttactttag gatgtgggtc ttggggtgga
     1741 aattcagtat ctgaaaatgt aggagttaag catttactta atattaaaac agtagctgag
     1801 aggagagaaa atatgctttg gtttagagca ccagaaaaag tttatttcaa aaaaggttgt
     1861 ttaggagtag cattaaaaga acttaaagat gtaatgaata agaagagagc ttttattgta
     1921 acagatacat tcctttacaa taatggatat actaaagcag ttactgattt attagatgaa
     1981 atgaatatta agcacactac attctttgaa gtagaaccag acccaacttt ggaatgtgct
     2041 aagataggcg ctaaagctat gagagaattt aatccagatg taataatatc tataggtgga
     2101 ggaagtgcaa tggatgcagg aaagataatg tggacattgt atgagcatcc agatgtagat
     2161 ttccaagacc tagctatgag atttatggat ataagaaaaa gggtatatac attccctaaa
     2221 atgggtgaaa aagctaattt tgtagctata ccaacatcag caggtactgg ttcagaagta
     2281 acaccatttg ctgttataac tgaccaagat acaggagtaa aatatccatt agcagattat
     2341 gaactgatgc caaatatggc tatagttgat tctgatatga tgatgaatat gccaaaaagc
     2401 ttaacatctg cttctggtat agatgcttta actcatgcat tagaagcata tgtatctatg
     2461 cttgcaaccg attatgcaaa tggattagct ttacaagcta ttaagagtat atttgaatat
     2521 cttccacgtg catatgataa tggtgcaaaa gacccagaag ctagagaaaa aatggcaaat
     2581 gcttctacaa tggcaggtat ggcttttgca aatgcatttt tgggtgtttg tcactctatg
     2641 gctcataaat taggtgcttt ccaccatgta ccacatggtg ttgcaaatgc tcttttgata
     2701 acagaagtta tgaaatttaa ttcttcagat gcaccaaaga aaatgggagc attctctcaa
     2761 tataaatatc cagaagcatt aaagagatat gctgaaatag cttcattttt aggattaaaa
     2821 ggaaattctg atgaagagaa attccaaagt ttattggtag ctattgaaga tttaaaactt
     2881 aaagttggta ttcctaaatc tataaaagag tttggcgttg aagaatctaa gtttatggat
     2941 tcaatagatg aaatggtaat tcaagcattt gatgaccaat gtacaggagc aaatccaaga
     3001 tatccactta tgaatgaaat aaaagatatg tatttaaatt catattatgg aagataagtt
     3061 tgctataaaa tagataaaat aaaaactctt atacataaaa caaagtttta ttgtataaga
     3121 gtttttttgt ttgagaaaat ggatagtttt tattctttaa tttaaaattc aattaaatag
     3181 tgttattata ataataaaag aatgttttta tggttattat gttgatttta tgtgtaacat
     3241 ttaagaatag ttatatacaa tataaatgat gaattggtat aaaaaggata tattatctat
     3301 atgaagtatt gactaattag gggaggagtc gaatgacagg gagaaataaa agttttacat
     3361 taattacaat tcttttttta acatcattat ttttgacaat ggggtatatc tatatagaag
     3421 atacaaaaca tcttcttatg tcagaggcaa aaatacatat aaaagaagtt gcagtacaag
     3481 gctctcaact agcacaaaga caaattgaaa aagatttaga tgttttaaat attttttcta
     3541 actattatgc ttcaaatcca gatataccta atgaggaaaa aatgaaaaat cttttagatg
     3601 aaatggaaaa tcaaaaattt tacactatgg caatagttga tataaatggt aatgctgaaa
     3661 ataccaaagg tgataagttt tcagtgaaag atagagaatt tttcaaaaac tcaattaaag
     3721 gtaagaagta tgtttcaagt ccatatgttg atgaagtaaa taagtctata aagaagattg
     3781 ctatttcagt accattatta aataatgata aagtagttgg agttttatat tgtacttaca
     3841 atatcaatac tctgatgaaa cttattaata tatcttttta tgaaaataat agtatatctt
     3901 atgttgtaaa aaataatggt acaattatcc ttcatccaca aggggatagc ctatcaaaaa
     3961 atatttataa attgttaaaa caggataatg atattcaaga agtaaataga ttaaaaaaag
     4021 aattgcaaga aaataaaaca ggtgcaactg tattaaatat gttggaagaa agaagatatt
     4081 taggatatgc cactatggat aatgggaata gtgaaaataa ttatataaaa gactggaatt
     4141 taattttttc aattccagaa actgttgtat ttagtaattc aaaacaaata atcaacagag
     4201 ctgtatatgc agtgttatct attgtattaa tatttattgc aattattttt tatataattt
     4261 atataaaaaa atctaatgaa aaagaaatat taagtttggc ttatgaagat aaagttacat
     4321 atataggaaa tcaaaataaa ttttatagag aatgtagtaa gtatctttta gataaaccat
     4381 ctttaaatta tattatagta tattttgata ttaataactt taagatgatt aatgatactt
     4441 ttggatatga atttggtgac aatttattaa ttacaatagc aaaagcttta aaagaagaat
     4501 taacagaagg tgaggtatat gcacgacttt caagtgatta ttttgcaatt ttctgtgatt
     4561 ataaaaatgg aagaaataaa attataagaa aacttgataa tatacgaagt aatattgaaa
     4621 gtaatttgag tatagtcttt gaaatttctc tgtgtgtggg tatttatttt gttgaagaag
     4681 gtgaagtaga tattcaaaag gctgtaaata aagcaaatat ggctaggtct gttgctaaag
     4741 gtaaaaatat aaattatgct atttataatg aagatgttag gaataagctt agtgaggaat
     4801 caatgatttt agatgatata aaaatagcat tggtaaaaaa tcaatttgaa gtgtattatc
     4861 aacctaagtt tgcacttgta actggagaaa tgatagggag tgaagcacta ataagatgga
     4921 atcatccaga acatggtttt ataagtcccg cagtatttat tccaatagca gagaaaagta
     4981 agttgatttt aaaaattggg agatttgtat ttgaaagggt ttgcaatgat ttatatgaat
     5041 ggaaaaagca aggtaaaaag atagttccag tttcagtaaa tttatctagg gtcgagttgt
     5101 atcaaccaga tattgtaaaa tttatcaata aaacaataaa aatgtataat ttaagttcag
     5161 atttcattga aatagagata acagaaactg tggctattaa tgagttaaat attttaaaga
     5221 atgttttaaa tgagttgagg acgtatggat tttctatttc tatggatgac tttggtacag
     5281 gatattcttc tattagttgt ttaagagata tgccaattga tatattgaag ctagataagt
     5341 cttttcttgg tggcattgaa catgatgaga gaagtcgcaa tatagcaaaa tcaatagtgt
     5401 ctctagcaaa atcactagat ttagttgtaa ttatagaagg tgttgagagt aaagaacaag
     5461 ctgagttaat gaaacaattt ggatgtgatt tagttcaagg attttatttt gcacgaccaa
     5521 tgccagctaa gaatttttta gatttacttt aaaacaaaat ttgattttta tataaagcac
     5581 tattatgaat gcttgatttt aataaatcat tgctaaataa ttagtgtttt tttattttat
     5641 caatgtattg tctaatataa agcaaaaaat aattgtattt tataaaaatt atattaaaaa
     5701 taaatttatt ttgctaataa acatgttatt aacaaaagaa tagtactata atgtatagat
     5761 gataaaaact ttaataaaaa tttagtgtat aggagttgtt taagtatgat agatataagt
     5821 attgatgaca aacttaagga aagatggcct aatgctaagc tgggttgcat tcaagcaaaa
     5881 gtagcagtaa ataaaagctc agaaaaatta attaatgaaa taaatgagtt ttgtgatact
     5941 ataaatcaaa gtctaaaagt tgaagacatt acgaaactag ataaaattaa agatgcaaga
     6001 aatgcttata aagagcttgg aaaaaatcca agtagatata gaacatcttc agaagcattg
     6061 gttagaagaa ttattcaagg gaagggtctt tatacaataa ataatatagt agaaataaac
     6121 aatttaatat caataaaatc attatatcca gtaggtacat ataatgtaag caaattacat
     6181 tcaccagtat gttttactgt aggagatgaa ggagaacagt ataagggtat tgggaaagaa
     6241 ttaataaata tagaaaatct tcctatattg tctgattcag tgggtaaatt tgggagtcca
     6301 actagtgatt ctgaaagagc aatgataaca gaagatgcaa atgaaatatt aatttgtata
     6361 ttttctttta gtcaagaatc tgatattgaa gaatattttg gatatgctaa ggaattactt
     6421 aaagaatatg cagatggaaa agatatagaa actaaaataa ttaaatagaa tctatataac
     6481 aacgttatgt taagctaaaa ttcaatataa aaataagtta agataaagaa actaacacaa
     6541 aattagtttc ttttttaaaa tagtagttta gtgttacaaa aatagataga tagtcccacg
     6601 attattaaaa gtatggtaat atattaatat agcagagatt gtgtttaagg gattttgaaa
     6661 ggggggattt ataataatca ttttatctaa aagataaaat ggttttatag aaataactat
     6721 atatttaaaa atataaataa tgatacagta atttgggtat ataaaataag gcatacatgg
     6781 ttttgtttaa aaaccaataa ggtacatagg taattacaat gtaaggaagg atttaattat
     6841 gattgatgga aaagaggtaa aacaagaaag tggacaaaaa aatctaaaat ttaagatagc
     6901 tatagtagta ggtgttttgt ttgtagctta tataggaatg gcaatctttt ttagaaatca
     6961 tttttacttt ggaacgacta ttaatggcgt aaaggcttca ggaaaaacag ttgagcaagt
     7021 aaatgatttg ttagcatcta gtactaattc ctatacttta aacttagagg aaagaaacaa
     7081 taagaaagaa caaataaaag caaaagatat tgatttaaaa tttacaccag atgataaagt
     7141 tcaaaagata aaagatagtc agagcgctat tggatggatt ggtggaatat ttaaatctaa
     7201 agagtataat aatatgataa ctctttcata taataaagat ttactagaaa aaaggtttaa
     7261 tgctttatct tgttttgata gtaaaaatgt tgtagaacct aagagtgctt atcctaagta
     7321 tgatagcact aaaaacgctt atgttatagt accagaggta cttggaaaca aagtgaaaaa
     7381 agatgatttt tataagttag tacaaaactc aattaattct gggaatactt ctatttctct
     7441 ggatgaaagt aaagtttatg aagcaccaaa caacacaaag gattcagaaa agttgaaaca
     7501 agctattaag acattagata agtatgttgg tgtagtcgtt acatatgatt ttagtgaccg
     7561 taaggaaact ttagatggtt ctgaaattaa taaatggtta aaagtagact cagaaaagaa
     7621 ttatgacata acttttgata atgatgctat ggtagaatat acaagaggtt taagtaaaaa
     7681 atacagtact tttggtgact caagaccatt taaaactgcc acaggtaaag atattacaat
     7741 ttcaggtgga atttatggtt ggttgataga taaaaagaaa gaagctgaag cattagttga
     7801 tgttgtaaaa gctggtaaaa atgttacaag agaacctatt tacatacaaa aagctgtatc
     7861 tcgtaataaa gatgatattg gaaatacata tgtagagatt agtctttctg gccaacatat
     7921 gtggttcttt aaaaatggag aaatgcttgt atcaacagac gttgtaacag gtgatttagc
     7981 tagaggattt gctacaccat caggtatata tcctcttaat tataaggcta gaaatgtttc
     8041 attaactggt caaggttaca gttcacctgt aagttattgg cttccattta atgggaacat
     8101 aggcattcat gatgctactt ggagaaattc ttttggtgga agtatatata agtcttcagg
     8161 ttcacatgga tgtgtaaata cacctttttc taaggcaaag aaaatatatg aaaatataga
     8221 accaggtaca ccaattattt tatactagta aatgtgttgc taacagttaa gcgaagtcat
     8281 cttagtttat ttaggatggc ttccttttta tataaagctt attgaagttt acagaaagac
     8341 tacttaaaag gagaaataca taatgaatga aaaattaact aaaattttag aagaagctaa
     8401 gaatgatgat gaatttagaa aggaacttat aaaaacaaga gaacaacgtg atgttatgga
     8461 ttcattttgt aaggttgtta catctagagg ttatgatatg acagtagggg aacttttttc
     8521 tatgggagaa gaatatacat ccaatctact gaaaagtgta aatggaggag cagcatatcc
     8581 tattgaagat tggagtgatt ggtacgagga tttttttata atgttgtcga atatatagag
     8641 taactaatga tattatctac ttaagattaa tacattgcct taaaataaaa ctattagaac
     8701 taggtgtaag ttttatcaat ctttaaaaat attgatttat ttctaactag atataaaaaa
     8761 attagattaa aaataaggtg acaaaaatcg atatagcttg atgatttata aaagttagat
     8821 aaaatagtgc gagatatttc taaaaattca aaaaaaacaa taaacttcaa tggttagagg
     8881 ttgaaaaaga atataaaaaa cttttatatg taataaatta aattaaaatt ataaaaaaaa
     8941 taaaataaaa atttaaaatg tcgacataac gttaatttta aaacaaaata acgctattga
     9001 caaactatat cgctttaaat tataattatt gaaaataatg gtatttaaaa accatactca
     9061 tgtcatagtc taaaagtaag tcaaaaaagg atgtaaatct aggcaagtac tattctaaaa
     9121 tatgttttat taagaaataa acgttgaaaa atattaatta ttatataaaa atgctgttta
     9181 tactttaaca atgaggtagt aatctaatta gaataaaaaa atctaattgg ttatatacat
     9241 agtaaaaagg taagagaggt gatttggatg gcttttgaaa taataaaaag cattgttgag
     9301 gcagagcaga cagcagacag tatcaaagta aaagctgtta ctgatgcaga gtctatcaga
     9361 gctgatgctg taaacaaatg tgaaagcata tttgctgatg taaaaaaaca agcaaagctt
     9421 atggaagaaa ctcttattga gaaggcagtc accgacagta gagcagaggt tgataaaatc
     9481 ttagctaatg ctaaaagtga atgtctgaaa attgaaaaaa ctgctgaaga aagaaaaagt
     9541 aaggctattg aagcggttat tggaaaggta gtgagataat atggcaatag ttaatatgaa
     9601 caaaatatct attgttggct tagaagctca aaaaagccag attttaaagc tacttatgaa
     9661 ccgtgggttt gttcagattg atgatagtgc ctttcttact gaggaggagg aattaaaaaa
     9721 ttatcttgta aaagatagtg aagaatctga agttataatg ctagagcaga aaatgtctca
     9781 tgtaaaccaa gcaattaata ttgtttcttc actagtgaaa caaaaaaaat ccctacttgc
     9841 accaaaaaga gagtttaaca aaattgatag tgaaaaagaa gggcaagttt atgctgaagc
     9901 tctggagtta aacaatttgc acaaggagat aggtacaata aggtctaaca taaacttact
     9961 taacaacaat aaaagtatgt tagaaccatg ggtgaacttt gatattccta ttgaaaatat
    10021 ggaaactaag tatacaaaaa ctatacttgg aactgtgccc ataagcgcaa acattgatgc
    10081 tttaagagta aaattagaag atgaaatacc agaaagtgtt attgggattg tcaattctga
    10141 caagttaatg aactatgttt atttaattac tttaaaagaa acttttgatg atgttttaga
    10201 agttttaaaa gaatttaatt tttcagtggt ttcattacca aatgaagaag gtacaccgtt
    10261 acaagctatc aagaaataca atgaaatgat aattagacag gaaaacgttt ctaaggacaa
    10321 aacagaggaa attaaaagac atgcagatag tatacacatg cttgaaaacc tatatgattt
    10381 ttacactata gaaagagacc aaaaaaagat tatagagaga cttgtcaaaa caaaaacaac
    10441 attctgtctt aatggttggt taccaagcaa aagggcagat gaattaatta aagaaattac
    10501 agaaaagttt gattgttgtg ttcagactga agaaggaagt aaagaagaag gcttcccaat
    10561 tctgcttgaa aacaataaat tagtaacacc ttttgaaagt gtaactaaca tgtacagcta
    10621 tccaagtaca aaagatattg acccaaatac aattttaact ttcttctttg ttgtattctt
    10681 tggaatgatg ctaagtgacg ccgcatatgg gttaataatt gcagtagttt gtggatttgt
    10741 tgtatataaa ttaaagatac aaaaaggtga aggaaattta attaaactta ttggtatctg
    10801 tggagtttca actactgtat ggggtcttat attcgggggt attttggggg atttaattcc
    10861 tataaaagca ttaattaatc ctttagagga tgttatgaca cttatgggaa tgtcgttact
    10921 gttcggtatt atccatatat atgtaggttt gggaataaaa gcatatacat taataagaag
    10981 tggaaaggta atagatgcaa tctttgacat aggtttttgg tatttgtgta taacaggtgt
    11041 atgtctactt ataatacctt ttgttgcagg ggacataggt gtattttcag aagtaggaaa
    11101 atatttagca attataggtg ctataggtct tgtacttact caaggaagaa gctttaaagg
    11161 tattcctgtt aagcttttta aaggattttc aagtctctat ggtataacaa gttattttgc
    11221 tgatatatta tcttatacaa gaattatggc gctttgttta acaacaggag ttatagcaca
    11281 agttatcaac cttttaggag ctatagctgg tccgatactt gcagttgtaa ttggtgttgt
    11341 aggacacaca ataaaccttc ttataaatgc actaggtgca tatgttcata caagtaggtt
    11401 acagtatgta gaatttttca ataagtttta tgaaggcgga ggagttcctt ttgttccgtt
    11461 taagtataaa acaaaatata caagcattaa taaaaaggag atgtaaatat ggaattttta
    11521 aacgcgttag gaaatggtca atttttggca atatcaggag ctgctatagc agcattattt
    11581 gcaggtatgg gttctgctaa aggtacttca atagcaggtc aagccgcagc aggtgttgta
    11641 acagaagacc ctagtaaatt cggtcaactt ctagttttac aacttcttcc tggtacacaa
    11701 ggtctgtatg gatttatcat agctttcctt attttatcaa aagcagggat tattggtgga
    11761 gatgcaatac caacatcagc tcaaggttta caacttctta tggcaggact tccaattggt
    11821 ttagttggtt tagtatcagg tatagcacaa ggtaaagcag cagcagcagg agttggaata
    11881 gttgcaaaaa gacctgaaga acttggtaaa gctataacat ttgcagcaat agttgaaaca
    11941 tatgctcttt taggactact tgtttctttc ttagcttaca atggaattgc aattggttaa
    12001 ttataaatta taattcataa gtaaaaaaat gaaaaggagg aagcactcct atgggtaatg
    12061 aacaaaaaat gattgacaga attatagctg atgccaaaca agaagcacaa gaaatattgg
    12121 ataaagctaa aagtgaagca gatttaaaag taaattcagc taatgaaaaa gctgaaaagg
    12181 aaatggcttc ctatacaaag cttgcagagg cagaagcaga aaaagcggct tctaaggaaa
    12241 tatcaggagc ttatatggag gctaaaaagc aaatattatc aaaaaaacaa gagattttag
    12301 aagaggtaat tttagaagct aaaaacaaac ttttaaatct taaagataat gaatatgaag
    12361 agattatact aaacatgatt gaaaaatcaa attgtacaga tgattcagag atagtattat
    12421 ctaaaaaaga taaaaaaaca ttaaaagatg tgctatcaaa aaaaggcatt aaagtgtctg
    12481 atgaaactag agatattact ggaggtttca tagttaaaaa aggtgacatt gagtacaatt
    12541 attcatttga agccataatt gcagtagagc atgaatatat tgaacaaatt gcagcagaaa
    12601 ttttgtttaa ttaaggaggg gttaaaaaat ggcagaagaa aaaacttatc cctatgccgt
    12661 tgcacgaata agagtgcttg aaaaacagct tcttaacaga caaatgttta ttcaaatggc
    12721 agaagccaaa agccctgaag actctttaag aattatagct gaggcaggtt atgctgatac
    12781 atcaaataat aatatacata attttgagaa tattttgact caagaattat caaagacata
    12841 tgaaattctt aaaagtctag ctcctgaaga aaaatttgtt gatgtatttc tttataaaaa
    12901 tgactatcac aatttaaaag tgctgattaa agaagaaatt tctggtgtag atggtgagaa
    12961 atatttaatt gatggaggta caattcctct tattaagctt agagaatctt tagcaaatcg
    13021 tagttttagt gatttaccta agataatgtc atcagctata ttagaggcat ttgatgttta
    13081 taataagaca caaaatggcc agatggttga tattgttcta gataaagcaa cctttaccag
    13141 tatgaaagaa actgctaaag aaagccaaaa caaatttgta atagattatg ttatgaaagt
    13201 ttgtgattta acaaatctaa agagttttat aagagtcaaa aatatgaaga aagattttga
    13261 tatgtttatg aatgtgtttg tttcaggtgg ctcacttgat aaggaaaaat tcttagaagc
    13321 tttttcctca gatactccag catcatgttt taaatctact tcttactctg atgtctgtaa
    13381 aaatggcatg gatagtggtt ttactgtctt tgaaaaactt tgtgatgact atcttatgga
    13441 atatgttaga ggagcaaaat ttaagcctct tacattagaa ccactaattg catatttata
    13501 tgctaaagaa tcagagataa aaacaattag aattattttg actagtaagc ttaataatat
    13561 agacgcagat actataaaag aaaggctaag ggatgcttat gtataaggta ggagtagttg
    13621 gagataaaga tagcatcatg ggatttttag ctcttggaat agatatcttc ccagcctatg
    13681 atagtgacga aattaaaaaa agtatacata agttggttga agatgaatat gcgataattt
    13741 atattacaga acaggcatca ttgcttgcaa aagaatcaat agcaaaatac aaagattacc
    13801 aacttcctgc cattatagtt attccaggta ttggaggaag tatgggatta ggtatgaatg
    13861 aagtaagaga atctagtaaa cgtgctatag gtgcagatat attatttaaa gaatagatga
    13921 aagttgaata aaagacaatc tcaaatttta ttggtgctaa atatatgtac taataaaata
    13981 taggagggaa tatttaaatt ttgataaagt atatgattgc aggtgagaga atatgaaaac
    14041 aggcacaatt gtaaaggtgt caggaccgct tgttgtagcg gagggcatga gagatgcgaa
    14101 tatgtttgac gtcgtaagag tttcagataa acatcttata ggcgagatta tagaaatgca
    14161 tggagataaa gcttctatac aggtttatga ggaaacttcc ggtctaggac caggggaaga
    14221 agtagtttct cttggaatgc ctatgagtgt tgaacttgga ccaggtctta tttcaactat
    14281 ttatgatggt attcaacgtc cacttgaaaa aatgtatgat atttcaggta ctaatataac
    14341 taaaggtgtt gaagtatctt cacttgatag aacaactaag tgggaattta aacctaaaaa
    14401 atctgttggt gataaggttg tagcaggaga tataattggt ggcgttcaag aaacagcagt
    14461 agtagaatgt aaaattatgg ttccttatgg agttaagggt actataaaag aaatatattc
    14521 tggtgaattt actgttgaag atacagtttg tgttattaca gatgaaaaag gtaatgatat
    14581 acctgtaact atgatgcaaa aatggccagt tagaaaagaa agaccatata gagaaaagaa
    14641 aacaccagat tcacttcttg ttacaggtca aagagttata gatacatttt tcccaatcac
    14701 aaaaggtggg gtagcagcta taccgggacc ttttggaagt ggaaaaactg ttacacagca
    14761 tcagcttgct aaatgggcag atgcagatat agttgtatat ataggctgtg gcgagcgtgg
    14821 aaatgaaatg acagatgttc ttcttgaatt tcctgaatta aaagacccaa gaacaggcga
    14881 gtcacttatg caaagaactg tgcttatagc aaatacatca gatatgccgg ttgctgcacg
    14941 tgaagcttct atatacactg gtattacaat agctgaatat tttagagata tgggatatag
    15001 tgttgcactt atggcagact ctacatcaag atgggctgag gctcttagag agatgagtgg
    15061 tcgtttagag gagatgcctg gtgaagaagg ttatcctgca tacttaggtt cacgtcttgc
    15121 tcaattctat gagagagcag gaaaggtaaa ttgtctaggt atggatgaaa gagaaggaac
    15181 acttacagca attggtgcag tttctcctcc tggtggtgat acatcagaac ctgtcagcca
    15241 agcaacgctt cgtatagtaa aagtattctg gggtcttgat gcatctttag catataaacg
    15301 tcatttccca gcaattaact ggttgactag ttattcactc tatcaggaaa aagttgatgt
    15361 atgggcagat aaaaatgtaa atgataattt ctcagctcaa agagctcaag ctatgaaact
    15421 tttacaagtt gaatctgaac ttcaagaaat agttcaattg gttggggttg attcactttc
    15481 agatggagat agattgatac tagaggttac tcgttctata agagaagact tccttcatca
    15541 aaactctttc catgaagttg atacttatac atcacttcat aaacaatata gaatgatggg
    15601 acttatatta aaattctata agtcagcaca agatgctatc aagcaaaatg ttactataaa
    15661 cgatattatc aagctttcag ttcttgaaaa gattggtcgt gctaagtatg tagaagaagg
    15721 cgatatagat gcagcttacg attcaattga agatgaaata gacaacgagc ttgcagacct
    15781 tattaaaaag aggggggctg aagaactatg ataaaggaat ataagtcaat acaagaggta
    15841 gccggtcctc ttatgttaat aaacggcgta gaaggtgtaa aatttgatga acttggagaa
    15901 attgaacttt caaatggaga aattcgccgt tgcaaagttc tagaggtaaa tggagatact
    15961 gcacttgttc agcttttcga aagctcaaca ggtataaatc ttgctgaaag taaagttcgt
    16021 tttttaggaa agagtcttga ctttggagtt tcaccagata tattaggtcg tgtttttagt
    16081 ggaatgggta gacctattga tggaggtcca gaaattatac cagataaaag acttgatata
    16141 aatggagctc caataaatcc agcagcacgt gattatccgg ccgagtttat acaaactgga
    16201 gtctctgcta tagatggact taatacattg gttagagggc aaaaacttcc tatattctca
    16261 gggtctggtt tgccacatgc caatcttgca gttcagattg caagacaggc aaaagtacgt
    16321 ggaactgatt ctaagttcgc cgttgtattt gctgcagttg gtataacttt tgaagatgct
    16381 gaatttttta taagcgattt taaagcaact ggtgcaatcg accgttctgt agtgtttgta
    16441 aaccttgcaa atgacccagc tgtagagcgt gtatctacac ctagaatggc acttacagca
    16501 gcagaatacc ttgctttcga gcaagatatg catgtacttg ttataataac ggatattaca
    16561 aactatgcag aggcattgcg tgaagtttca gcagctaaaa aagaagttcc aggacgtcgt
    16621 ggatatccag gatatcttta tactgacctt gctactatgt atgaaagagc aggaaaaatg
    16681 aaagggcatg aagggtctat aactatgatt ccaatactta caatgcctga ggatgataag
    16741 acacatccaa ttcctgacct tacaggatac attacagaag ggcaaattat acttagccgt
    16801 gaactttata aaaaagatat acagcctcct atagatgttt taccatcact ttctcgtcta
    16861 aaagataaag gtattggtaa aggtaagact cgtgaagacc atgcagatac aatgaaccag
    16921 ctttttgcag cttattcaag aggtaaggat gcaaaagaac ttatggctat acttggtgaa
    16981 tctgcacttt ctgagattga tttaatgtat gctaagtttg cagatgaatt tgagaaagaa
    17041 tatgtttcac aaggatttag aactgataga actattgagc agacattaga aatcggatgg
    17101 aagcttctta gtatgttacc aaaaagtgaa cttaaacgta tccgtgatga atattttgaa
    17161 aaatatatgc ctaaggagtg atatctgtgg ctagattaaa tataaatcca acacgtatgg
    17221 aaatgactag acttaagaaa ctccttaaaa ctgctacaag aggtcataag cttcttaaag
    17281 ataaacttga tgaacttatg aaacaatttc ttgagattgt aagagaaaat aagcgattgc
    17341 gtgaagaagc agaaaatgct cttgatactg cttataaaaa ctttataatc gcaagagcag
    17401 ttatgagtca ggagtatctg ggttcagcac ttatgatgcc aaagcaatca gtttcagtag
    17461 atgtttctac gagaaatata atgagtgttg atgttcctgt gtttgacttt aaaactgaaa
    17521 acaatcaaag tgatatttat ccttatggtc ttgcttttac atcaggtgaa ttagattctg
    17581 ctatggaagc tttctcagat gctatgcaac cacttttaag acttgcagaa agtgaaaaaa
    17641 gtgcacagct tcttgcacaa gagatagaaa agacacgtag acgtgttaat gctcttgaaa
    17701 atgtaatgat accaaattac attgagacta ttaagtatat agctatgaag cttgaagaaa
    17761 atgagagagc aagtactact agacttatga aggttaagga tatggtgctt aaaaaagcac
    17821 ttgaagaaaa gaaaaaaaat gatttggttg tataattaaa tacttataaa aataagtcta
    17881 acattctact ttatagaggt tagacttatt ttttatgttt aaattaaaat gtagatacta
    17941 taaaaattaa tatattgttt aaaaacagac tgtatttaac taaaaataat atatttaaca
    18001 aaaatttcta aaaattaacg aactgttaat ttacacttaa ctttatatta acaaattagg
    18061 tgtattatat aaacataagc aaaaacaata aaaaacaaat aaaaaaaggg aaaaacacaa
    18121 aggggggaag atatgaaaga atttatattt acttgtctgt gcattgtagt gattacattt
    18181 atgacaagtt gcatatcaac aacaccacaa actactcaag gaaaaggaaa taataaactt
    18241 acaatatatg cagcactaga ggaagagcag atagcttatt atatggaagg ttttagagaa
    18301 gagtatccca atatagatgt agagatagtt atggattctc atggtgtaat agcttcaaaa
    18361 ctattagcag aaaaagataa tccacaagca gatattatat ggggattatc agcaatgaac
    18421 atgatagagc taaaaaaaga tggtgcactt gaagcatata agcctaaaaa ttatgataaa
    18481 gttgataaaa aatttaaaga tactgaagat gatgtatctt gggtaggaat gagtgtccca
    18541 gagacagcaa tagtagttaa ttataaggaa cttaagaaac taggtataga tattccaaaa
    18601 agttatgaag atttaataaa accagaatat aaaggactta taacaatgcc aaatccagca
    18661 tcatctggaa cggggtatct tacagtatca gggcttattc aaatgatggg tgaaaaagat
    18721 gcttacaatt acatggataa attacataaa aatatagcca catatacaca ctcgggttca
    18781 aaacctgcga agttagctgg ctctggagag tatccaatag gtattacact tggatataga
    18841 gctacacaac aattatctag tggagaacct atagaggttg tatttccaaa ggaaggttca
    18901 ggttgggact tagaagcaaa tgccttagtt aaaaaagata atataaaaaa agaagcaaag
    18961 ctatttttag attgggcaat aagtgattca gctatggata gatatgcaca tgaagtagca
    19021 gttacttcca taaagacaga taatccagtt ccaaaaggtt attctaaaca accatttgaa
    19081 cagcttataa aagaagttga tttaaactct gctgccaaaa acagaagtac agtacttaaa
    19141 acttgggaat caaaatacgg ttcaaaatct gaaagtaagt aaagtttaaa ttaataattt
    19201 agatgaaaga attttagaag aaaaagtagg atataaaatt taaaataaaa aaataactat
    19261 ataaggagag ataagatatg agttacttaa aaataaataa tgtgtttaaa agttatgacc
    19321 aaaaaaaggt tttaaataat attagtttgg atattgaaga aggggaattt ctatgtttac
    19381 tcggacctag tggatactat atgttagtcc aaataattat ataaaattaa tagtgatgtt
    19441 tttgttatta tctatttcta tataatctat tatagataac caaaaacgtc tgcgttcaac
    19501 cctgcttaaa tcactataca tctcattaat atcaatatct aagaattttt ttatatgtga
    19561 tgtatcaata atttgactct cctgttcttc agttatatta tccagttgag attgtaattt
    19621 ttcataatct tttctataag tctctttatc aatcaaatcc tctaaatata aatctttgat
    19681 tttatctaat tttttcatga ttttcttctt ttcatctttt ttgttagatt tcttatttcg
    19741 tctgattttt tcattttgtg cttctaattt caccatatgt ttatgtaatt gtggttttaa
    19801 gttagtcaaa aggtagtttt ctatatgttt ttcattatga gttacattgt gtacacagtt
    19861 tttatttaga tagaatgtag aacatctata agataaataa agtttttctc caacattact
    19921 agaattaccc tttaatgtat aaccacactc cttacatttt aaaagaccag aaaaaatatg
    19981 ataatgtatg tttttattag gagtagtttt tttatttttt tctaatattc tttggatttg
    20041 tttaaattgt ttttttgata taataggttc acaataatct tcaacataaa atcctcgttt
    20101 attatagatt cctatataaa gttcatttct tagtatattc tttattttat tataactgta
    20161 taattcgcca tgaagattat taattgtttc tattaaagtc ctaacagaac ctgatttctc
    20221 gtattcgtca aatatagctt taactatata ttttttttct ttatcaataa ctagatgctt
    20281 attttctatt ttgtaaccta tgggaattgt accacttata acttctttac gtctcaattt
    20341 atcctgaaaa acaaatttta ttctttcaga tgtttgagct gcttcatttt ctgctacaga
    20401 tagcataatg tttatatgta atctaccagc agcagtgcta gaatcgtagt tttctaaaat
    20461 ggttttccaa tcacacttat gtttttccaa ggtttccatt attttataat agtttttaac
    20521 gccacgactt agtctatcaa ttttagtcat taaaactagg tctactttat ctttttccac
    20581 atctcttaat aatcgttgta agttaggtct ttttaaatta gttgcagagc aaccttcatc
    20641 aatgtattta ccaactatgt taaaatcatt ctctttagag tactgttcta aagcctctat
    20701 ttgtgtcctt atgctatctc catttaaagc ttgttcttct gtactaacac gtatataaag
    20761 tgctactctt aacattttac attccccctt attgtatatt taagaggagc tgaacggctc
    20821 ttaaatatac tatgaattgt tacaaaaaat ttgcattcat aatactaaat cttggctcaa
    20881 aaaatatcac ataattatct agtgtagctg aaaaaccata tttactttta taacattcta
    20941 aagcttcatt tagaaacttt tcagttacat caaggtattc tgccatttcg gttatagtct
    21001 tacagccagc attaaaacta tctattatac ctttaagacc aattaacttg ttgtaagcca
    21061 tcaatctagc tttatattct tgtttgctat tttcaacttt atttaggtct aatatatttc
    21121 catatgaagt ataatgatgt cctagttctt ctgctaacac acaagctttt tcacttatat
    21181 tattaagtgt atttttattt aaagctattc tattattttt atataatcca tgagaatttg
    21241 aaattaaagg aacttctcta acaataatat tattatcatc tgcttcagag agtaactttt
    21301 cataactatt cataagttca cctacctatt ttaccaatta tccatatcat ctaaatcttg
    21361 atatattttt tcaatttctc cttcttcatg taaatgttca ttgtgtgccg ctattgtgtc
    21421 tatgtgattt ttatttacat atttacctat ttgagtaagt tcatctactc tttttattgc
    21481 ttcattttgt ccaatatcgt ttaaggcatt aaagcttgat aaaagcttat tttctttaat
    21541 tttaatttgt ttgcagtctt cgttccaccc cattataaaa gcaggagatt catctaatgc
    21601 atgtgctaaa atttctagct tatcaagagg aatatttttt atagctcccg tttcatatct
    21661 ctgtaaagtg gacttactta gtccagtctt gttagctaaa tcttgataag acatattaag
    21721 ttctaatcgt ttatttttta ttctatttgt aatctccaac atttttaaat cattttcagt
    21781 attcaaattt atcacctcta taaaatatat tataaagtat tttttcataa atgcaacaca
    21841 tatattggaa aatataaaaa aatgttgcat ttttgacttg acaatataaa atggatgtat
    21901 taatattgaa ttatcccaaa taagcaacga ggtgatggaa tgaatataag taaattaaaa
    21961 ggaaaaatgg tcgaaaagaa atacactcaa aagaaattag cagaagagtt gggtatgact
    22021 gttcaagctt taaatgcaaa attaaataat cgttcacaat tcaagattga agaagcagtt
    22081 aagatatcaa atattttgca aatcgaagag cctggtgaga ttttttttga caattatatc
    22141 ccaaaaatgc aacgaaatta aataagaaaa cctaacagat aaaaattaaa actagggagg
    22201 tagaaattat gagtaataat ttacaagtaa tagaaagaaa caacaaaaga gttctaacta
    22261 cacagcaact agcagatgta tatgaaactg actcaaagaa tataagtaac aatttcaaca
    22321 ataacaaaga taggtttatt gaaggtaaac attatttttt attacaaggt gatgatttaa
    22381 agaattttaa aggtattcat acggaatatc aagtgattta agtaagaatt aagttaaata
    22441 aaacaagtac cttgaaaact aaatacagaa tattcaaaag aggtgattag atgcaaatag
    22501 agcaaacaac aatacgcctg cctatataag gcgaataagc ccaaaagagg acttattctt
    22561 ttgtttcttt gcatttttca gcatttaatt tttctaaacc taatttgatt aattcaatag
    22621 tagcttgtgt tcttgtagag aaccttttat caaacctaaa atcatcaatt tcttttaaaa
    22681 gttcatcatc aacagttatt gtgaaccttg gtttttgagt agccattaca tcacctcacc
    22741 ttaagtgtat tatacaccag tggtgaaatg gtgtaaatat aaaaaataaa aatataataa
    22801 aaaagtgttg acatggttca ccagttcatc tataataaaa atataaagag gttcaccact
    22861 ggtgacaaaa ggaggatgaa aatgccaact aaatcaaaaa gaatttcaat aactatattt
    22921 ccagaattag aaacagattt agatgtttta aaaaaggaaa agttttataa agaatctcaa
    22981 agtgaaatgc taaggtatct tattaaactt gggcttcaag taaataaaga aaaggtctat
    23041 aaaaacgaat aaaagaggag gtataagcat gaatgaccta acaataatca agcaaaataa
    23101 tcaattctta gttgagagta gagaagtcgc agagttaata gaaaagaaac atgataattt
    23161 gttaagagat ataagaggat acaagaaaat tttagaggac tcatcaaatt tgaggagtca
    23221 ggattttttc atagaaagta cttatataaa tactcaaaat aaaattcagc cttgttactt
    23281 attaactaaa aaaggttgtg acatggtagc taataaaatg acaggtgaaa agggaattat
    23341 atttacagcg atttatgtaa ctaagtttga agaaatggag cgagagttaa aagaacaaca
    23401 acctaaacta ccaactacat acaaagaagc attgcaacag ttattaatag aagttgaaga
    23461 aaaagaacaa ttacaattag aaaatcaaga aaaagataag gtaattcagt tacagcaacc
    23521 aaaagtactg tttgctgatt cagtagcatc ttctgacaat tcaatcctag ttggagaatt
    23581 agcaaa
//
LOCUS       DAEPUT010000062        23349 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.064, whole genome shotgun sequence.
ACCESSION   DAEPUT010000062 DAEPUT010000000
VERSION     DAEPUT010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23349
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.064"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(1..765)
                     /locus_tag="KRL22_002626"
     CDS             complement(1..765)
                     /locus_tag="KRL22_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH1273098.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            1039..1713
                     /gene="fsa"
                     /locus_tag="KRL22_002627"
     CDS             1039..1713
                     /gene="fsa"
                     /locus_tag="KRL22_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH1273099.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKERKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHRVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(1835..3229)
                     /locus_tag="KRL22_002628"
     CDS             complement(1835..3229)
                     /locus_tag="KRL22_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HBH1273100.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(3307..4653)
                     /locus_tag="KRL22_002629"
     CDS             complement(3307..4653)
                     /locus_tag="KRL22_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1273101.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKRHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVTQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     regulatory      4903..5005
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            5099..6475
                     /locus_tag="KRL22_002630"
     CDS             5099..6475
                     /locus_tag="KRL22_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH1273102.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(6589..7734)
                     /locus_tag="KRL22_002631"
     CDS             complement(6589..7734)
                     /locus_tag="KRL22_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1273103.1"
                     /translation="MNTFEQLKISSTIIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            7987..8694
                     /locus_tag="KRL22_002632"
     CDS             7987..8694
                     /locus_tag="KRL22_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273104.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            8741..10336
                     /locus_tag="KRL22_002633"
     CDS             8741..10336
                     /locus_tag="KRL22_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273105.1"
                     /translation="MSNLSILIKNNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKKINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNVYIILASIL
                     TLILDFMIWRIISTKGVKIFKNL"
     gene            10440..11522
                     /locus_tag="KRL22_002634"
     CDS             10440..11522
                     /locus_tag="KRL22_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH1273106.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKENKVNSNLDKVIEKLN"
     gene            11671..11832
                     /locus_tag="KRL22_002635"
     CDS             11671..11832
                     /locus_tag="KRL22_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HBH1273107.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            12173..13441
                     /locus_tag="KRL22_002636"
     CDS             12173..13441
                     /locus_tag="KRL22_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH1273108.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            13636..14424
                     /locus_tag="KRL22_002637"
     CDS             13636..14424
                     /locus_tag="KRL22_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH1273109.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRILETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            14424..14873
                     /locus_tag="KRL22_002638"
     CDS             14424..14873
                     /locus_tag="KRL22_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH1273110.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            14877..17141
                     /locus_tag="KRL22_002639"
     CDS             14877..17141
                     /locus_tag="KRL22_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1273111.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPESSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGRMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            17281..17592
                     /locus_tag="KRL22_002640"
     CDS             17281..17592
                     /locus_tag="KRL22_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273112.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            17878..18378
                     /locus_tag="KRL22_002641"
     CDS             17878..18378
                     /locus_tag="KRL22_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBH1273113.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            18435..19421
                     /locus_tag="KRL22_002642"
     CDS             18435..19421
                     /locus_tag="KRL22_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH1273114.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            19471..20193
                     /locus_tag="KRL22_002643"
     CDS             19471..20193
                     /locus_tag="KRL22_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HBH1273115.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            20222..22156
                     /locus_tag="KRL22_002644"
     CDS             20222..22156
                     /locus_tag="KRL22_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1273116.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNKYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            22149..>23349
                     /locus_tag="KRL22_002645"
     CDS             22149..>23349
                     /locus_tag="KRL22_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HBH1273117.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKT"
BASE COUNT         8957 a         2508 c         3780 g         8104 t
ORIGIN      
        1 ttataaaaca tttacattaa attctgataa aatatctact atatcaggag taggcgtttt
       61 ttctgtaatt atagaactaa tatcttctaa atgagcaaac ttgaaatttc catcaaattt
      121 aaacttttta tcttccataa ctataaatac ttttttactt gaatttatta tagccttctt
      181 cgtaagacca tcttcaattt caaaagttgt aagtgaagag ttgaatacat ctactccaca
      241 acttcccata aaagtcttat caaacttata tttcgatata aactctatag ttggagtacc
      301 aacaaaaccg tctaaactga gatttaataa acctccagtg gaaattatat ttaaattatt
      361 tggttttgaa gtaactacat ttagtatatc cagcatattt gtaacaagtg ttactttttt
      421 attactttca gctaacaact tcgcaagcaa gatgttaatt gtagagatat ctaaaaatat
      481 agtttctcta tcttcaatta aattaaatgc tttttctgct attattttct ttgttggaat
      541 attaatttct tttctgtctt ttgtatcctg attctctagt gtttctctag ctagtacagc
      601 tcctccataa attcttctta ttgaagaaat cttttctata ttttttaaat cttttcttat
      661 acaatcttct gtaacattaa atttagaact gagctctttg acagtaactc taccttcttt
      721 ttttaggata tttaatatag cttggattct ttcttctgca aacattttct acctcttttc
      781 gcaatatagt attatagtaa atattataag ataaaataca atatatcaac tattttaaca
      841 tgaaatacaa aattaattta atataaaaag tatgtttttt ctaactatat atttagaatt
      901 tagtaaataa aaaaattata aaactaagaa ggaaaagtaa aacaataata aaaaataaaa
      961 aacaataagc aaaatgttga aaataatacc aaatcaatat ataataagaa taaagaaaga
     1021 ttaaaggggg atattttaat gcaactaatc ttagatacag gtaatgtgga ggagattaag
     1081 gagttatgta cttgtttacc aatagatggt gtaactacaa atccaagtat tgtttcaaaa
     1141 gaaagaaaga attttaagca acttataaat gaaattggtg agattatagg tgaggatatg
     1201 cctatacatg ctcaagtgtt aagtacaaag tatgaagaaa tattagaaga agcattatat
     1261 ataagtagtt tgagaaaaaa tatatatgta aaaatacctg taacacaaga tggtttaaga
     1321 gctataaaag accttcacag aaaaggtgta aaaataactg ctactgcaat attcactgct
     1381 catcaaggtt ttttagctgc aaaggctgga gcaaactata ttgcacctta tgtaaatagg
     1441 cttgataata tatctggtga tggagtagct atggtttcag aacttataaa aataatagat
     1501 acttataaaa tggatacaaa agtacttgca gccagtttta aaaatgcaca acaagttata
     1561 gaattaatgc aacatagggt gcatagtgtt acagtaccat atgatatttg taaatctatg
     1621 atgaatcatc cattaactga ttggagtgta gataagttta tagaggattg ggagaatact
     1681 tttggaaaag gaagtaaaac aaataatatt tagtattatg gtaaaagagt agttttgtcc
     1741 aatttcacaa gaacttatat aaaaagatga aaatatgaat tttcttttta ataatttcgt
     1801 tattatctta agttaattca tattttcatc ttttttagat ttctagtcct ataaatttcc
     1861 accaagggaa tgttatacat attattataa agtaggttaa aggaatcaaa gttaaaccgt
     1921 atttgaaaat aaccttgcta ttatacagat tttcaccatg accaaccatt attgtagcat
     1981 gatgaaatgg taatatgtac tgtatgctta ctataatgta gacaaataga cataaagtaa
     2041 cactattttc ctttagtata tgtaaacttc caagtaacgg tattactaca gatgatgtag
     2101 tgacagcact tccaagacat atattcaaga ttattgtgag agttatcaaa aacaatattg
     2161 aaataatttc tgaagagttt ggtataaact ttatcaaata atttcccatt atatctacaa
     2221 ctccagagta ctttaacact cctccaattg aaaatgctgc tataaaaaaa ataaggacct
     2281 tccaatttat ttcttttaaa gtactaaatc caactatttt tcttagtaat aaaagaagta
     2341 cacaaattga cattataatt aatgtgttta tgttatgtat gaactgagtt aaaaacataa
     2401 aaaacattat tcctaggcat aaaaatacgt gtttttgctc tttgtttagc aaattaaatt
     2461 ctttttttaa attagaatat gaaaaatgaa gtttattacc ctcaagattt tcattagaaa
     2521 taaattttat tgaatgcaat tcttttttaa agacaaagat aaataaaaaa taagttataa
     2581 aacaagtaat tatagttgga acagacatat aaaaagccca ttgaccccaa tttatattac
     2641 aatttccaag ttctagtaca acataattta gaagagtgtc tccatttaca aaaaacattg
     2701 atgtaaaggt agatgctgta aatatactaa acaaaagtat agattttgaa tcttcagtta
     2761 tctgttgttc ttttaaaaac tccttgtaaa aagcagatac aagaataacc cttggaaatg
     2821 gttgtgggat aaaaaatatt aaaagtatac ctaaaatata cgataaaaga atcatttttt
     2881 taggggtatt tacagtattt aaaattaact tctcagaaat aatttttgcg acacctgttt
     2941 ttgtaactgc attagtaatt atgtatgcaa gaattattat gtaaaaattt tctgtaaata
     3001 aaaactgtaa aataaccttt attggtgcaa tgttaaatat aaacgctaga attacaaaaa
     3061 acaatgcaac aaaagttttt tcaactgagt ctacagccca tatcaagata gttaaaaaag
     3121 ataagcatat agaaaatttt atgttgaaac tgtaattaag agagaagtag agaattatgg
     3181 tagctataac agtcatataa aattgttttg gcttaagaat aatacccatt tttatattca
     3241 cctccataat ttattatatc ataatggagg tgaatacaat gaatgtgaat acattttata
     3301 aaaagattat tcattgattc tatgatttac aatagcttta gttttccaat gtcctttctt
     3361 atagtagata actgtaacaa taagacctaa agtccaacca aaaggaatac ccatccaaat
     3421 tccgtctgtt ccaaaaaatt tagaaagcat ataagaagct ggaagtcttc caagccataa
     3481 agatactatt gagcttataa gtgcaaacat ggaatcacca gcacctttca ttgcacttga
     3541 aagtacaaaa gaagttccaa taaataagaa gaatggtcct attataaata agtaagaaga
     3601 gccaatttta atgacatctt tatcagtatt gaatagagca attagatttt ccctaaatag
     3661 caaaattaaa gcaataactg taactgctaa aactaaggtc atttttatag attctcgaat
     3721 gcctttttta actctttcat tttctccagc acctatgttt tgagtaacaa aagtagaaac
     3781 agcagaacca agattcataa taggtaagct tataaaattt tctatcctaa gaccagcacc
     3841 aaaagctgcc atagcagatg taccataact attaactaaa aattgaagag ccatatttcc
     3901 aattgaaaac aacatttgtt gaactccact tggaagtcct aatctaagtc catctttaaa
     3961 tattttgtta tcatatacaa ttcctttgat tttaaattta agcacttcat gtcttttatt
     4021 taaataaatt atacttatta taaatgatac tgcctgagcc attatagtgg caagtgcaac
     4081 gccctcaaca cccattctta gcactacaat aaaagttaag tctaaaacta tatttagaat
     4141 tgtggctatt atcagaaaat aaagtggagt tactgaatct ccaagtcctc taagtattgc
     4201 acttactgaa ttatatccag cagaaaataa tattccacta aatattatag taagatacaa
     4261 ttttgattga gcaaaaacgg attctggtgt attcataagc ttaagcattg ggccaccaaa
     4321 tactattcca agaatactta ttaatataga accaataaat aaaagtatat atgtagtatc
     4381 aatagtagct tttacctttt ttaaatctcc tgagccataa aattgtgaca ctaaaataga
     4441 aaatccaagg ctaacaccca taagcgctgc caccaataaa aacattatag ggttagctcc
     4501 agagactgcc gccattgctt cttttccaat aaatctacca actattatac tgtcagctgt
     4561 attgtatagt tgttgaaata aactaccaat aagcataggc atggcaaaaa agaatatgga
     4621 ctttccctca tgacctgtag ttaaatcttt caccttattc ctccaaataa aaaaattatt
     4681 aatttattat agtataatct taacataaac tttatatcca aactataaat aaattgtatc
     4741 aaaatatcat atattttttt aaaatgtaaa gaatataatt ataatttgaa tttaataaat
     4801 caatatttaa tataatcgaa tattaataca aaatcaatac aatatatacg tatatattga
     4861 caaaattaat tatataaatt aaaataatat tcgtaaagaa aaattcatgt tttgtactgt
     4921 ataacatata attttgacaa tatgggtcat aagtttctac cggaataccg taaatattct
     4981 gactatgtat actattattt agttaattaa atatttaatt aactgaatta tgaaggatac
     5041 ggctcagctt atcaactact gtgtcgtttt tttgtaaaat ttaataggag gtgttgttat
     5101 gcaaacaaca aacagtagta ctatgcagaa actttttcca attttgacta ataaaaatgt
     5161 cgacatgaag aaggaaataa ttgcaggagt aactactttt ttaactatgg cttatataat
     5221 agctgtaaat ccaaatattt tatctgagac aggcatgcct gcaggtgcac ttgttacagg
     5281 tacttgttta gcagcagcat ttggatgtat tttaatgggt gtagttgcta accttccttt
     5341 tgctttagca tcaggtatgg gtcttaatgc attttttgca tatacagtag ttttacaaat
     5401 gggtgttcct tgggaagtag ctcttacagc agtatttgta gaaggtatta tttttatagt
     5461 attatcagta agtggagttc gtgaggctgt tgtaaatgcg ataccaaaaa atatgaaatt
     5521 agctgttaca ggtggtatag gaatatttat tgcacttata ggtctagtta acagtggaat
     5581 tgttattgga gaccaagcca ctcttatcaa aatgggtaga tttacaccag cagtaataat
     5641 aacttgtgta ggattaataa ttattgctgt attagataaa aaaagagtta aaggttctat
     5701 actttttgga atagtagtga gttcattact tgcttgggca tttgctttta taaatccaga
     5761 gtatgcacaa aaattaggta tatatttacc tggtggatta tttaaattcg aaagtttagc
     5821 accaatagca ggtaaaatag atttaggata tgtactacat ccaacaaata taggtggttt
     5881 tttagtagta gtttgtacat ttttatttgt tgattttttt gatacagtag gtacattagt
     5941 tggtgtttgt tctaaagcaa acatgttaga tgaaaaaggg aatgttccta atgtaggtag
     6001 agccttactt acagatgcgg ttgcaactac agttggtgca ggacttggag tatctacagt
     6061 tacaacttat gttgagagtt caacaggagt tatcgcaggt ggaagaactg gatggacagc
     6121 aataacagtt ggaattttat tcttagctgc aatgtttttc tctcctgtat ttatagcaat
     6181 tccatcatgt gctacagcac cagctttaat atatgttgga tatttaatgc ttggtacagt
     6241 taaggatata gagtttgata atataactga aggtgttcca gcttttgtta ctattgcttg
     6301 tatggcatta acatatagta taggtgatgg tttaacttta ggtatattaa cttatgtttt
     6361 cgtaaatata ttttataata tatttggagc taaaaaggca gaagacaaaa aacatgtttc
     6421 tgtagtaatg attgttctgg caatattatt tataataaaa ctttggctac tataataggt
     6481 attatttaaa attttaattt aatataaaat aaagggctgt aatttattat caattgtgat
     6541 gataaactac agctcttttg tatttgttgt atttttgtat ttattgtatt atttaataat
     6601 gtctattagt tctccatttt gtaaagtttt aggtgtaatt actatattga actctttttg
     6661 caaatctttt ataatatcta attctttttt tgttattatt gagattgtgt taccacttcg
     6721 atttcctcta gcagttcgac cacatctatg caggtattca tttttacttt ttggaaaatc
     6781 caagttaaaa acatgactta catccacaat atctagtcca cgagcagata aatcagttgt
     6841 aattaaaatc tttgctttac caagtttaaa tttatttatt gcattctttc tatcttcttt
     6901 ttccatattt ccaaaaattc ctattgcttt gtaattatga taatttagtt ttgatactag
     6961 gacttctata tttttttcat tatttacaaa tacaatagct ttttttggat ttgtagctgc
     7021 taatgccttt ctaagaaaag taaatttatc ccttatctca cctaataaat atgagtgatt
     7081 gatgttagga tttatttgtg atttttcctt tgtttttatt atttcaaact ccttcataag
     7141 tttatcacaa atttttatag tgctatcagt aagacttgca gagcatccta taatttgtct
     7201 atctcttaac gttgttctta ttatgtcttc tatacaagtt atattttttc cattcaatag
     7261 attgtccact tcatctaaga caatagtttt tatattatgt gattttagtt tcttttgttt
     7321 tatcaagtct aaaactcttc cacaagagcc aattactatg tgtggtttta ctgcttttat
     7381 attttttatt tgtttttgta tattgacctc cccaattaaa gctaaagaag taacggagag
     7441 ttctgcattt ttagccaata attcaacctg gtttgtaatc tgcattacta attcatgcgt
     7501 aggtgcaagt ataagagctt gtgtttctct ttttgatgta tcaatttttt caaatatagg
     7561 taaaaggtac gctagtgttt ttcctgttcc agtctgtgaa ttaatcaata aatccttatt
     7621 ttgaattata ttccctataa caagtgactg aacttctgtt ggagaagtta tgtcttgttt
     7681 tttgagtcca tctattatag tggaacttat ttttaattgt tcaaatgtat tcatatttta
     7741 ctccttatat tttaataatt atagtcaact attttttatt atacattgtt tattcaaatc
     7801 gaactatata ttcttttata attatgtgta atttgaaagt aaatatcaat tatatttatg
     7861 cctttatatt tctgatacct ttgcatttta tagatttcta aaataaacaa ataaaagttg
     7921 taattgtttg atatttgtta tatattatat ataacaaata tcaaaactat aatatggagg
     7981 gaaattatgt taaaagtaat caatgtatct aaatcatata aaaataaaaa agtagtaagt
     8041 agtgtctcat ttgatgtaaa tgatggagag ctttttgggt ttataggaca taatggagca
     8101 ggtaaaacta ctactattaa agcaattgtt ggaatacacg attttgaaga gggagaggta
     8161 ctaataaatt ctaaatctat aaaaaaacag cctgttgaat gtaaaaagga aatggcatat
     8221 atacctgata atccagattt atacgagtca ttaactggta tacaatacct taattttata
     8281 gctgacatat ttgaagttgc caaagataaa agagaagagt taataaaata ttattcaaat
     8341 aagtttgaac tcaataaagc attaggagat ttaatatctt catattcaca tggtatgaaa
     8401 caaaaattag ctataatttc ggctttgata cacagcccaa aaatcttaat tcttgatgaa
     8461 ccttttgtag gtcttgaccc aaaagcttcc tttatattga aggaaattat gagggagttt
     8521 tgtgacaaag gtggttgtat atttttctca acacacgttt tagaagttgc tgaaaaaatt
     8581 tgtgataaga ttgccataat aaaagatgga aatataattg cttatggaac tacagaagaa
     8641 gttaagggaa gtaattcact tgaaagtatc tttatggaat taatagagaa ataaaatgtt
     8701 ttttatacaa tatagtgtct aaagtgagga atgataaaat atgagcaatc taagtatatt
     8761 aataaaaaat aatataataa atgaatttaa attaaatgcg ttaaaaaaag ctgatggtag
     8821 agaaaaacaa aaaataatgg gaatgatgct ttcagttgtt ataatagcgg gtctattaat
     8881 tttttatgta acgagcttaa gtctctcttt agttgatatc ttaaagaaaa taaatcaact
     8941 ggaaatgcta ctgatatttg gttttggatt atcaacatta acaactattg ttacatcatt
     9001 atataaaacg tcatcatatc tatttcaagc aaaagattta gaccttttga ctagtttacc
     9061 tataaaagaa tctactgtac tagcaagtaa gatattaatg ttggttggag caaactattt
     9121 attttcttca atatgtatga ttatacctgc agtggtttac tttttaaatt ctgatgtaag
     9181 tataacttat ttcccttatt tgatattgct atttttagct ttaccattat taccgatagt
     9241 tgcttcatca ataatttttc tatttatagg gcagatatca tcaagaataa aatacaaaaa
     9301 tttagtatta atcataggta gcattatatt gatgttgctt tataccctac ttatgtcaag
     9361 acttaattct atgtcagttg aaatgctaaa gaatagtgtg tctatttcag agacgattag
     9421 aaaagtatat cctcctatat attattttgt tgatgctctt aaaacaggaa gtatagtttc
     9481 atttttagca tttatagcca tctcaataat accatttttt atgtttgtaa ctctgtttgc
     9541 aaaaaaattt aaagatataa atgctaagat gagtgaagga tataagtcaa aaaattatga
     9601 atttaagggt caaaaaactt caagaccttc aaaagcttta ttaaaaaaag aatttaagag
     9661 atatacttct tcgtttatat actttttaaa ttcatctgca ggtttgttat ttctaatagt
     9721 aggtacaatt ttaatattat tatttggagc agataaagtg ggtgagttac tgaaattgaa
     9781 tatagatttt aatcttataa aaatacaatt attgggagta ttcttcttta taatagtaat
     9841 gaattgtaca acatactgtt caatttctct tgaaggaaaa aacttatgga tactgaaatc
     9901 ttctccaata gatgaaagag aaatattctg gtcaaaaata ttgatgaatt ttttattgaa
     9961 tgccccatta tctattttat gtctaatatt agtatctata agattagact ttgaaattca
    10021 gtttattatt gtatcaatct gtttgattgt aagtttttca atgtttgtag cattgatggg
    10081 attattatca aatttattat acccaaacct tgattggaaa aatgaggtgg ctgtagtaaa
    10141 aagaagtgca agtatgatag ttacaatgtt agtatcatta gcttatgtaa ttatacttgg
    10201 aggtatatat gtattacttg gaatttcgtt tttaaatgta tatattattt tggcaagtat
    10261 acttactttg atattagatt ttatgatatg gagaattatt tctactaaag gagtaaaaat
    10321 atttaaaaat ttataggtgt atttatgtca aataaagact tatctttttt agtcttgcaa
    10381 ataataggtt aagtagttat actatgtata gtgatatgaa aaaatttagg agaaaataaa
    10441 tgagaaaatt atccaaaaga gaaaaagatt ttattcaata tggattttta ttatttttga
    10501 tatgtattac tacttattta gtattaacta ctttagatat aaaactaata cctaaaatta
    10561 taaggctagt aaataagact tatatatttc ttggcatatt gacaattata gtatatatga
    10621 taattgaatc tattgtaact catttgataa taaatgcagt tcaaaaaaca aaagtaaaat
    10681 ttattggtat taaaatggct acaatgggat tttactataa cttagttact ccatttgcat
    10741 ctgggagtca accaatgcaa atatatgcac ttacaaaata tgatgtaagc cttagtaaat
    10801 cagtggctat agttactaat aaaactgtag tatttcaaag tacagttact gtattttgtg
    10861 gaattttaat tttgctaaat aagtcattac tgatggagca agtacattct gtgaaagtct
    10921 tgataacttt tggaatgatt atgaatgtaa gtatgttgtt aggtggacta ctaatagtat
    10981 ttagtccaaa acaagtaaaa atgatagcag aagttttgat taatttttta tctaaattta
    11041 aaacatttaa atttttagat tcaaaacgtg atagaataaa tcattatatt gatgattata
    11101 attattctat aaaaatattt attaaaaatg taagaatctt agttttaagt atattactta
    11161 ctgtgttaca attaatcgca tatttcagta tagtttattg tgtgtataaa gcctcaaatt
    11221 taagaggagt ttcatatgta catataatga cattacaggt ctttttatat atggctatat
    11281 caccaattcc aacaccagga aatgttggag ctaatgaggt tacatttttt actatgttct
    11341 ccaatataat tccaaaagaa ttattggggt actctgtact cttatatagt gggtttgtat
    11401 actattttat attaatagtt tcaggtttat ttacatttgg aacgcattat acattaaatt
    11461 cttggaaaaa ggaaaataaa gtaaattcta atttagataa ggttattgaa aaattaaatt
    11521 aataaaataa ttagggaaat tctatatata aatatggtgt tgaataagct atattatatt
    11581 gagatatttc ccttttttga ttaaaattat agaaatttga aataataagt aataaacaga
    11641 aaaagtgata ttgttttgaa aggagaaact atgaaacaag ataaacaaaa tgaaaaacaa
    11701 agtgagattt ctaagataaa acaaagcaat gataataaac ttgaaatagc tcaagaatta
    11761 catgtaagta aaaatatagg gaatatgctt ggatatagaa tagataagaa aaaaatgaat
    11821 agaccaagtt aatgaaaatg ttgaaaatgg gacattttaa aaaatatata taatgaaatg
    11881 ttttattgtt aaatttaaac ttattttaat gaagtaaaaa gtcgaaaaat atctaaaaag
    11941 atatggatat aaaaaatatt aatatatata tactataaac ttgacaaaat caacctttta
    12001 ataactagca aaaaatagca aaattatata agcgttattt aattgtcaaa aatgaaagct
    12061 aaattgcatg tcctaaaaaa aatgattgat aacatttatt tgtgtgctat aattatatag
    12121 taaaacaata agtatattgc ataatgtatg caaatcggga ggagagacgg acatggaagc
    12181 atctatacac acaattgcca gcaataattt attgataatt tttgctattg taagtataac
    12241 tggaataatt tgtagtaagc ttagtgaaat aataaaggtt ccagatgtag tgttatattt
    12301 acttgtaggt attttaatag gaccatcatt tttaaaattt atagatattc gtggatttca
    12361 aatagaaaat caactaatac ttacatttgg ttctgcattt attttatatt taggtggaaa
    12421 agaaataagt ttaaaagtat tgagaaatgt gaagatatct gtattcttat tagctacttt
    12481 aggagttgtg atatctgctt ttataatgca acaagtaata ggatttactt ttgggataag
    12541 tgcaatgact gctttactag caggaactat aatagcatca acagacccag ccactcttgt
    12601 acctatattt aatcaggtaa agataaagga tagggtaaag caaactgtaa taagtgaatc
    12661 agcttttaat gatgcaacag gagctatact aacatcagca gtgttggctg taattttgtc
    12721 aaataaattt tcattaggtg aaaatattta tgaactgggg acaatggtta ttgtcggagt
    12781 tttagttggt ttaattacag gaatactgct tttgaaatta gttaatgata aaccttatgg
    12841 aatatttaaa gattttgcac caataatatc tgttatttca gttgtagttg catatgaatt
    12901 atctacaaaa ttaggtggaa gtggatatat gtcttgcttt attgtaggta taataactgg
    12961 taacaagaaa aactttaaaa tttggttaag tcaaaaatct tatgatgcag atttttatgt
    13021 tgctgaaact ttaggtacta tttgtcgtat ggcaatattt ataatattgg gtagccaagt
    13081 taatttggct cagttaagta aatattttat gccatctgta attacagtat tagtattaat
    13141 gtttatagca agaccacttt gcgttttagt ttgtacactt gtagacaggg aagcaaaatg
    13201 gagtaaaagt gaaatattat ttatgatgtg ggtaagggaa acaggcgtaa taccagcagc
    13261 actttgtggt attatttcag caatgaaagt tcctggatac gaagtgattt catctgtagt
    13321 attcatgact atactaatta cattagtaat acaaggaagt actacaaaat tagtagctaa
    13381 aaaacttgga ttattagaag aagaagtgat aaatataagt gaaaaagtat caacttttta
    13441 aagttttgct ttaaaatagt acctgttaat ggctatttta atattgtcta atgatgatta
    13501 ttgaaatagt cattttttta tgtataagta atttacagaa tttacatatt agacatattt
    13561 attatcaaaa tttgttgaag ctatgatata attagttgta tttaaaataa gaatagcaaa
    13621 taagggagga aatttatgtt tacggttatg gatattgtac agccagatac agtagaagaa
    13681 gcgtactcaa ttttaaataa aagaaaaact aaccaagtaa ttggtggaag tgctttttta
    13741 agaatgggga aaaaaagaat aggaacagga atagaattat ctaaattaaa tttagattat
    13801 ataaaagagt atgaagatta cgttgagatt ggttctatga ctacttttag aatattagaa
    13861 acaagttcca taataaaaaa taattttgga agaataatag aagattcagt taaaaatata
    13921 ataggagttc agtttagaaa tgtagtaaca gttggtgcaa cagtattttc taaatatggt
    13981 ttttctgact tgatagtagc attactttca ttagatacag aagtagaatt atataatatt
    14041 gggagaatta gtcttgaaga gtttctaaat agagattatg agaaagattt acttattaag
    14101 atatacataa agaagacaaa taagaatgct tcttataaat cacttagaaa tgcaaagagt
    14161 gattatccaa ttctaaatgt atctgtatca aaacatatgg aacaatttaa gttatgtgta
    14221 ggagcaagac cgcagaaagc tacgattgca aaacaagcta gtgaatttct atctaacaat
    14281 gaaatcaatg aaattaatat agataaagca gtagaaatag catcagaaga actaactttt
    14341 ggttctaaca tgagagcatc tagggagtat agaaaagcta tgagtaaagt acttttaaaa
    14401 agagctataa tggaggttat ttaatgttag taaagattaa tataaatggg aagaaaaaaa
    14461 gtgttgatat agaaccagaa gaatatctgg ttgatacttt aagaaaagtt ggtaatttaa
    14521 gtgtgaaaag aggttgtgac acaggctgtt gtggtttatg tacagtttta attgacaaga
    14581 aacctacatt atcctgtgca acactgacat tgagagcttt agataaagaa ataactacaa
    14641 ttgaaggttt agaaaatgaa gttaaagaat ttagtgaagt tttggtaaaa gaaggagctg
    14701 agcaatgtgg tttctgttct cctggcttta tacttactgt acttgcaatg aaggatgagc
    14761 ttgaaaatcc tacagatgat gaaataaagc attatcttac aggaaatcta tgtagatgta
    14821 cagggtatat gggacagtta agagctatca aaacttatct ggaggtaaaa tagaacatga
    14881 atatagttgg aaaaggaatc aagaaaatag atggaatgag tatcacaaca ggaaagcctg
    14941 tatatacaga tgatttatca gcaaaagatg ctttggtggt aaagatactt agaagtcctc
    15001 acgcttatgc aaaaataaaa gatatagata catcaaaggc agaaatggtt gatggtgttg
    15061 aatgtgtttt aacatataaa gatgtaccaa aatctcgatt tacacttgct ggtcaaacat
    15121 atccagagtc atctccatat gatagattaa ttcttgaaga tgttgtaaga tatgtaggtg
    15181 acgaagtagc tatagtggca gctatagatg aaaaaactgc aattaaagca atgaatctta
    15241 tcaaagtaaa gtatgaagta cttacacctg ttttggattt tgaagaggca ataggaaata
    15301 aaactatggt acatgatgaa gatagacatt gtaactttga tataggtatg caaagagaaa
    15361 aaaatatagt atcccatcat gattatacaa aaggtgatgt agaaaaagta ttaagtaatt
    15421 gtgatgtagt gattgaagaa acttattata ctcaagctca agcacatgca atgatggaga
    15481 cgtatagggc atacaattat ttagaccata tgggaagatt ggttgtagta agttcaactc
    15541 aaataccatt tcatgtaaaa agacatttat ctcgtgcact agaaatacca gctagcaaaa
    15601 ttagggttat aaaacctaga attggtggcg gatttggtgg taaacaaact gcatgtgttg
    15661 agattttttc tgcaattgtt actttaaaaa cagggaaacc agctaaaata atttatgata
    15721 gaaaagaaac ttttaattgt tcaacaagta gacatgcaat gagattaaaa gttagactag
    15781 gtgctacaaa tgatggcata ataaaggcaa tagatataaa agcactttct gatacaggag
    15841 catatggaga gcatgcttct acaactattg gtttggttgg agaaaaaact ttaccaatgt
    15901 ataataaagt tgaagcaaca agatttattg cagatgtggt atatactaat aagatgccag
    15961 caggagcact tagagggtat ggagcatcac aaggatgttt tgctgttgaa tcaactataa
    16021 atatgcttgc taataaatta aaaatggacc caacagattt aaggttaaaa aatgtggtaa
    16081 cagaaggtga aactacattt gcatatggta aaactttaaa tagtgtcgat ttaataaaat
    16141 gtataaataa aggcaaagaa cttattggat ggaatgaaaa atatccttgt aaacatcttg
    16201 ataatggaaa aattagaagt gtgggtatgg caattactat gcaaggttct ggtatacaag
    16261 gtcttgataa gtcttcagct gaaataaaat tgaatgactg tggagattat actcttatga
    16321 taggttctac tgatatgggt acaggaagtg atacgatttt agctcaaatg gctgctgagg
    16381 ttcttgatac aagcattgaa aatataacag ttatatcagc tgatactgac ttagttccat
    16441 atgacccagg ttcatatgct tcaagtacta cttatgtaac aggtatggca gtagttaagg
    16501 cagctcaaga cttaagagaa aaaataattt ctgctggagc aactaaacta ggtgttgaga
    16561 aggatgaagt agaatttgat ggtataaaat taactagtaa aaaaggtagc actttattat
    16621 tcgatatagc agttgattct acaattggtc cagatactaa tcaattaata ggtcttgctt
    16681 ctcatggtag cccagtatct cctcctcctt ttatagcagg ttttgcagaa actgaaattg
    16741 acacagaaac tggaaaagtt gatttagtaa attatgtagc tgtagtagat tgtggaacgg
    16801 ttataaataa aaatctagct aagatacaag ttgaaggtgg aattgttcaa gggattggaa
    16861 tggcattatt tgaagaagtt agatacacag aaaaaggaag aatggacaca aatacattta
    16921 tgcaatacaa gattccagct agatgtgata ttggaaatgt taaagtagat tttgttgaaa
    16981 cttatgaacc aactggacca tttggtgcta aatctgttgg agaagttgtt ataaatacac
    17041 ctttaccagc aatacaagaa gctgtgttta atggaattgg tgtaagaata aatacactcc
    17101 ctattacacc tgaaaaagtt tttatggaaa tgaataaata attatttatg aaaatttaga
    17161 ctagttttac atgttaaaca accagttatg tcatacctgt tgaaagatat ttaataagta
    17221 gttattataa tattatgaat tttacttata aaatacaaaa ttaaataagg ggatgatgtt
    17281 ttggctggta atctaaataa tatgagagca gtaaataatt ttagaggaga taagaacatt
    17341 ttagaatgtt tagtcagctt tgagggtcgt tcaataagtc agagaaaagt aagggtattt
    17401 tttaaagaaa aacaaaatca aatagaaatt gattttgcag aagaggaaat ttctaaattg
    17461 gttgaaaatg ttgttttaaa tacatcatat caagaaatgt tatatgatga aatagagaaa
    17521 caactggaaa ttgattgtat aggtacttgg atgatattat ctaaattaaa agatggtagt
    17581 agagttcact gattttaaaa taaattatta gagcctaatt ttaaggctct tttttgctgt
    17641 ttttaattaa caatagaaaa cttatcttta gtttgtatat aattttaata tcatatattc
    17701 tatatatata aaattgaatt tgtatgtatt atattgtata atgtaaaatg aattggaaaa
    17761 atagttcgat aaaataattt gtttttataa aattactgtt taagtttata gattttgtat
    17821 aaaataaagt tatgttatta atttttttag aaataaaact tttactagga gacagatatg
    17881 agaaaaaata gtattaatat agcactaact gcagcaatta cagcaatcta tgcagtttta
    17941 acattatcat tgggatttat aagttatgga ccaatacaat ttagggtagc agagattatg
    18001 atgcttttgg catttttaga taaaggatat atagtaggtc ttacattagg ttgtttttta
    18061 gcaaatgtaa taggaccata tggtgtacct gatataattt ttggaacatt agccacattt
    18121 ataagtgcaa gtatgattta tattactaga aagttaggta aacagaataa aagtacttta
    18181 gttatagctt ctttatggcc aactgttata aattcgattg tggttggtct aatgttaaat
    18241 gtattctttg ggcttccatt aattctatct atgatacaag taggttttgg agaatttgta
    18301 gtagtgacaa ttgtaggagt accatttttc tgctttttaa tgaaaaaata taaaaatgtc
    18361 attaatatta aattttaaat agtgtatagt aatttaatta attgagagta ttattagtga
    18421 aaagaggtgt ttatttgtcg aaggtaaaaa gattgactga tgtttggata tatattaatg
    18481 ataagcaaaa gtttacaata aaagagttgt cagaggaatt taatctttca gctaaaacaa
    18541 tacaacgata tttaaaagaa ttaaataaaa tgggacttcc aattcaagca gaacaaggta
    18601 gaaatggagg ttatagggtg ctaaataata gctatatacc tcctgttata tttacagaaa
    18661 aagaagttat gattatacta tttgcactta agtcacttca gatttataat tataagttaa
    18721 tggaaataga aattaattct ataatgagaa aagtaagtta tgaacgtaaa agcagtataa
    18781 aagtaggtat agaaaatatt aaaagataca ttggctttgt agctaatgat actaatgatg
    18841 gagattttaa gagtagtaat gtaactgagt tttttagagc ttcttcagaa tctctaattt
    18901 taaatattaa gtataagtgt ggtaatcaga ttttggaaaa aaacgtatgc cctataggta
    18961 tatatttaaa taagggagca tggttttcac cagcatatga ttgtaaaagt gataaaataa
    19021 tattagttca tatagataat ataattgata taaaaagaac aggagaaagt aaaaaaatac
    19081 atataaactt ggaagaatgg ttacatgaag tatataacaa tttatatgga aatagttcaa
    19141 ctactaaaaa atttggtgaa attatttatc taaatgtatt attaactaaa gaaggtgttt
    19201 ctaaaataaa ggacagttct tggaatttag atatggagct aaatgaagat ggtagtggaa
    19261 taattagtac attcataaag gttgaagata tagattgtta tgcttcgatt ttatttttta
    19321 ttggaaataa tgctaaggtt atagagccaa aatttttgaa taagctactt tatgataagg
    19381 ccaatgagtt aagatatttt tatgaagaaa atatggtata atatttagaa atgttgaaat
    19441 taaataatta ttaaggagat atacgttata atggaaaatt ttaataagaa tgctaaaata
    19501 attggtattg gagctgaagg tattaatata ataaatgaag tagaagaaaa aataaaagca
    19561 aatatggata tagaaaaaat aaacataaat caagagattg aaaaagaata tgttagaagt
    19621 cttttagatg gtgtagatat attatttttg atatattcat ctgaagataa acatattaga
    19681 gatattataa aagctgtttc atatatgtca aacgaaagaa gagttctatc tataggaatg
    19741 gattgttcag agaaagaaaa taaagaagat ttagagcttg ggagagagtt taaaatcaat
    19801 aatgatagta tatttaaatt tgttgattta atgaatatca tggtagagtc tatttctgat
    19861 tcttgcatga taaatataga tattactgat ttaaaagaag ctattgtagg agataaagga
    19921 attaagtatt cttttgaaga gtttgaagat acaaagtcat atagcgagat agctgacatt
    19981 ttatttgaca ggatggaata tattggtgag gaatttataa gtaagaaagg aattgtattt
    20041 gttgaaggaa gtccagaatt ttctataatg gaattgaatg atttaataag taatattcag
    20101 agcaaggtag aagaaagcta tgaagtaata ttttctttat atataaagga aaatttaaat
    20161 ggaaatatta gagtaggctt attgtataat tagtatattt tagatattaa ggagagtgta
    20221 tatgtctgaa aatataagag gtacagagta ttggttaatg gaagaatttt tttatcagga
    20281 aacagacaca ccacagattt ttagagaaga aagcataatt gcacttggat ttgacataaa
    20341 aataaattta aaaaaagtat tcagtatggg gaaaaaatca gaaaagtata ttaatgagaa
    20401 ttgtaatgat aaagatttta taaaaaagtt tatgtcgatt aaaaaaggag attatttttt
    20461 atataaagca tatcaaaata tagaagaaaa agttaaatgt aatgtgtcta ttggcatagt
    20521 tgaagaagat tttgaaaatg gatatgaatt aagtcatatt ttagggcata cactaccagt
    20581 aaaatggatg cataattttg atacagtttc aaattgtaaa gtatatacaa gtgaatttta
    20641 taaattaaat aataatgata ttagctcata tttagaaatt attaagtcac aagataagaa
    20701 attattgaga aaaagaatag aagaaagtga aaataataaa tggtatttaa aaaactatta
    20761 ttataaaaat gtagataagt gtgtagatga tgaagaatta tttattcagc ccattaatct
    20821 agaacaatta gaaagcctaa aaaatataaa gacagatgat tatattttat tgtataatag
    20881 cgagaaagta atttgtgaaa atgaccatac aatgaagagt ctatttggcg tatgtcaagt
    20941 tatggaaggg ttcgataaag agaaagtaag tgctttggaa ggtggatatt tttttcctgt
    21001 tagatggata gagtatgaaa aggagaatat agacggaaat gcatgggtta tatttgaaaa
    21061 taatagtata gttgaaaagt atgtaaaaag atttactaat aaaatgccat taaatactat
    21121 actttatgga ccaccaggaa ctggtaaaac atacaataca aaacagatgg tttacaatct
    21181 agtaagtgaa accagtctaa gaaacaaata ctatacaggt tacttagatt ataaaaacaa
    21241 tgtagaattt tgtacatttc atcaatcata tggatatgag gaatttatag agggtcttaa
    21301 gtctgatggt gaaggcaatt ttaagccaga agatgggata ttaaaggata tatctataga
    21361 agcatgttat aatgcattga aatttgaaaa aaagatgagc tttgagttgg aaaaagatag
    21421 cttgacttta gaaactataa aagacaggaa aaagaaatta gtattagaaa atatagaata
    21481 tagtgagagt tttaattttg aagaatcaga aaactatgtt ttaataatag atgaaattaa
    21541 tagagggaat gtatctaaaa tatttggtga gctaataaca ttattggaag atgataaaag
    21601 acttactaaa tcaaatcaaa ctattgtcaa actaccatat tcaaaggaaa aattttctct
    21661 acctccaaat ttgtatatag ttggaactat gaacacatca gataaatcaa tagcactttt
    21721 agatatagct ttaagaagaa ggtttaattt tgaagaaatt atgccagatt atgatttatt
    21781 gtctattgta gatggtatag atattagaaa aatgctatat acaatcaata aaaggataga
    21841 gtttttatat gatagagatc atgttattgg acaagcttat ctacttgctg tagaaaatat
    21901 taatgatata gtagtagtat ttagaagtaa aataatacca cttcttcaag agtattttta
    21961 ttatgattca gaaaaagtag gtttgatttt aggaggaatt ggaagaaatg aaaaagataa
    22021 atacattgtt tataaagaaa aacttatagc ttctgagtta tttaaaaata ataatgcctc
    22081 aataatggag agtaaagtta actattgtat aaaacaaaac atatctagtg aggagctaaa
    22141 aaatatatat gagtaaaaat atatatgtta aggaaaccta tgaatggata agggtaggta
    22201 atggtgaaaa tgagcttaca gaaattgaat atgaaaaatt gcttaaatat ctagagaaca
    22261 ataatgatgt attaaaaagt aatataatag atattaaata caaaaaactt agatttataa
    22321 actatgtagg catcatatgt tttgaaaatg taatacttga aatacttcct aaattgtcat
    22381 taagtgataa tcttgtaaaa gatagagaga tactattaca gatgctttct atatgtaata
    22441 aaattccaat tacaatgaat gaaaaaataa gattgagttt gaaaaattat aatctcttaa
    22501 atttttttgt tatgtatttc attgagagta tgcaaacaca gatgaaaaaa ggtatttatt
    22561 ttgaatatat aaataaaata gagaacttaa atgttatgag gggtaaaata ttattaagta
    22621 catatgcaaa agaaaaaggc atttctccaa tgaaaataag atgtgaatat gatgagtata
    22681 gtgaaaataa tttcttgaat caagttctta aaaaagcatg tatatctatt ttatgtagaa
    22741 taaatgacaa ttcaattcaa ggcaagatta aaaaaatttt aagctatttt caaaatgtag
    22801 atttaattta tatagataga aaaaaactat tggattataa attttataaa aacaatgata
    22861 gatttaaaga ttgttattta ctagctagac ttctactttt aaatttgtct atggataata
    22921 gtcaaaataa tcaagaggca ttttctatat tatttgaaat aaatactttg tatgaagaat
    22981 atataggaat tttaatcaaa agtatatggg acaattcatt tagagaaaca tatatacaag
    23041 ataagagtaa atttcttttg aaaaatgaac aaacaggtaa gaaaaacttt aatttaagac
    23101 cggatatagt tttatatgac ttaaaaaatg aatatgaaat tataattgac actaaatgga
    23161 aagctattga agtagattca aatgtttttt ataggtcaag tgatatatac cagatgtatg
    23221 catatataac agcatatgaa aatgcaaaaa gatgtatatt attatatcct tgtattcaaa
    23281 aagataagaa ttatagttcc tggaaattat cagaatcatt taagggtaag tttatagaag
    23341 caaaaactg
//
LOCUS       DAEPUT010000063        23274 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.065, whole genome shotgun sequence.
ACCESSION   DAEPUT010000063 DAEPUT010000000
VERSION     DAEPUT010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23274
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.065"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(190..558)
                     /locus_tag="KRL22_002646"
     CDS             complement(190..558)
                     /locus_tag="KRL22_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1273118.1"
                     /translation="MKKIPKSELLVMNFIWDKGIDKIPAREVANYMEISHGWTKGTTG
                     KVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISSLGC
                     GNEISDDDIKELEQWLKKRK"
     gene            complement(1086..1508)
                     /locus_tag="KRL22_002647"
     CDS             complement(1086..1508)
                     /locus_tag="KRL22_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBH1273119.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            1986..4889
                     /locus_tag="KRL22_002648"
     CDS             1986..4889
                     /locus_tag="KRL22_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1273120.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEEAEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLLPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYKISKSFAIKIEES
                     IGIKISDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            4922..5368
                     /locus_tag="KRL22_002649"
     CDS             4922..5368
                     /locus_tag="KRL22_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1273121.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            5491..5793
                     /locus_tag="KRL22_002650"
     CDS             5491..5793
                     /locus_tag="KRL22_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1273122.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            5974..7380
                     /locus_tag="KRL22_002651"
     CDS             5974..7380
                     /locus_tag="KRL22_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH1273123.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKHLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            7724..8782
                     /locus_tag="KRL22_002652"
     CDS             7724..8782
                     /locus_tag="KRL22_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1273124.1"
                     /translation="MGNKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            8881..9567
                     /gene="araD"
                     /locus_tag="KRL22_002653"
     CDS             8881..9567
                     /gene="araD"
                     /locus_tag="KRL22_002653"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBH1273125.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            9585..10232
                     /locus_tag="KRL22_002654"
     CDS             9585..10232
                     /locus_tag="KRL22_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH1273126.1"
                     /translation="MLDSLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKAIIPIVYESVNYGGYVDIASYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(10405..11772)
                     /locus_tag="KRL22_002655"
     CDS             complement(10405..11772)
                     /locus_tag="KRL22_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBH1273127.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(11962..12050)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            12478..14598
                     /locus_tag="KRL22_002656"
     CDS             12478..14598
                     /locus_tag="KRL22_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBH1273128.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKYLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKTCNKLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            14702..15955
                     /locus_tag="KRL22_002657"
     CDS             14702..15955
                     /locus_tag="KRL22_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HBH1273129.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(16109..17170)
                     /gene="ytvI"
                     /locus_tag="KRL22_002658"
     CDS             complement(16109..17170)
                     /gene="ytvI"
                     /locus_tag="KRL22_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH1273130.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNALFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            17444..18184
                     /locus_tag="KRL22_002659"
     CDS             17444..18184
                     /locus_tag="KRL22_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HBH1273131.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            18196..19974
                     /locus_tag="KRL22_002660"
     CDS             18196..19974
                     /locus_tag="KRL22_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1273132.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRILEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            20141..21058
                     /gene="pfkB"
                     /locus_tag="KRL22_002661"
     CDS             20141..21058
                     /gene="pfkB"
                     /locus_tag="KRL22_002661"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH1273133.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            21095..23014
                     /locus_tag="KRL22_002662"
     CDS             21095..23014
                     /locus_tag="KRL22_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1273134.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT         9280 a         2521 c         3931 g         7542 t
ORIGIN      
        1 atttaatata tttaaattta ttttagatat aaacatcatt ctgactacta ttaaaagaca
       61 tataaaataa ttaaacttaa aagtatattt gcttatcttt ttagtaaata aaatgaaaaa
      121 aagaattagt ggacttatgt aaatattaaa tttaataact tctataaata attccataaa
      181 atacgtctcc tattttcttt tttttagcca ttgttcaagt tcttttatat catcatctga
      241 tatttcattt ccacaaccta atgatgatat aaagctatga atagaatttt tatgtataag
      301 ctctaaaaaa tcctttgttt caaattttag atattcctca tgtttaactt taatagtgta
      361 taaagtattt ctaccatctt tttcaaattc taaaaaacct ttatcactta atctagaaag
      421 tactttacca gtagtacctt ttgtccatcc atgagaaatt tccatataat tagctacttc
      481 tctggctggt attttatcta tgcctttatc ccatatgaaa ttcataacta acaactcgga
      541 ttttggtatt tttttcaata taatcactca cctttaactt gattatatta gacaaatgtc
      601 taatagtcaa tataatatat catcatgtat aaataatctt tatattattt tatgcttgag
      661 aactaagtag tatagattta tagataaaaa agatattgag agttttatgg aagaggggaa
      721 tatattttct attagagata agaatatgac atatattttt tattgatttg tacaaaaata
      781 ctatatagtg aataaattaa tatcttttct aaattagaag aggagaatct tattagataa
      841 agattatcct ctttattgaa agtttaaggg atattagaga ttattaattt ttctctcttt
      901 ttttaactaa aagcaataat acataaaatt attattgcta atgatactct taatgtggta
      961 tatagtcata gtgtcgcatg tttatcaata gttttttcat taattattgt aacgaatagt
     1021 aggactcata aaatacttag aaatatgttt ttagatagat tttaaatata taatctaact
     1081 tatatctata aattaacact attattctcc aattccattt ctagtttttt tataaattta
     1141 ttaaattctt ctggttgcct ttttccaaac aatactctta caagagctga attgattttt
     1201 ccaaatatat tcctcttgct ctcactttca ataaaaataa gttttgtatt ttctaagtca
     1261 atatgtacta attcatatct agtaatagta ctttctcttt tattgcttgt ttttatctca
     1321 tatactctat ttttttcgaa attagttatt tcaaccttaa atcttttatt atttttttgc
     1381 tgtacaaatg ttcctactgc ttttttctca ttaaaattag gaaaatttag tcttgcagat
     1441 tttgtaaata tattaaatat gtcttttgca gaatatttta ataaaacttc agttttaaat
     1501 gtattcatat cgttttccct tctgtatata aatttaatat ttataagtta atttttaagt
     1561 taaaatagta taatatgcca tattaaatca tgttaaaact atttatatag ctaaaatctt
     1621 acctatataa gtatgtatac tatcatataa aaataaaatc ttaaaataga aagggttaaa
     1681 aacacagttt attataattt ttattgttga gtagatacgt actattatat atgattgagc
     1741 aagtttttca atcataaatt tataaagtat tttgcattaa aatttaaaca aagagttaaa
     1801 ttatttaaga ttatgaataa ctaatacatt tagtaaatta ctaaatatac aaaatgtaaa
     1861 tacttatcaa aatgtataaa tacttatgac atctagttac ttacagggtt taagtagaaa
     1921 aaaatatcaa agtaagtatg gcatgatagt tgcttatata tttatcaaga aaggagttat
     1981 taagcatgga gttgagagat aaacttgtaa acatcataaa tacagaaaat aaaaaagatc
     2041 cattaacaga tgttcaaata gcaaagtttt taagtacaac tagagagaac ataactaatt
     2101 tgagaaaaga acttaatata agtaattcaa ggcaaagaag atatccttat ttaaaatcag
     2161 caatttcggc aatattacaa aagaataaga atatttctat atcagaaatt acaagggaat
     2221 tgatgacaga aggctttaat atatcgagaa gagttgtgga ggaactttta cctaaagaaa
     2281 gtttagaaat ggatgtagta gaggaagctg aagaagaatc gaatgaccca tttgaaactc
     2341 tgataggtaa taaagggagt cttagaaatg ctgtagagca ggctaaatct gctatattgt
     2401 atccaccaaa agggttacca acgttgatta ttggggaaag tggagttggt aagagtttat
     2461 tttctagaca tatgtatgag tttgcaaagc aaaaaaagat agtaaaagag agctccaatt
     2521 ttgttgtatt taactgtgct gattatagtg acaatccaca attattatta tctttgttat
     2581 ttggatataa aaaaggtgca tttacaggtg ctgaatatga tacaccaggt cttgtagaag
     2641 aagctgatga aggagtttta tttttggatg aaatacatag attgcctcca aaaggtcaag
     2701 aaatactatt ttctatctta gataggggaa agtttaggag attaggtgaa actaatgctg
     2761 aaagaaaagt aagtattatg ttgattgggg caactactga aaatgtagag actaatttat
     2821 tattaacatt cagaagaagg ataccaatgc taataacttt gctaccatta catgatagat
     2881 tactaaaaga gaaaatagac cttatataca atatctttca acaagagtgt aatagaataa
     2941 atgcaaaaat atttgtagat aaaaatgtga ttgaaatact tgcactaaaa aagtttagtg
     3001 gaaatatagg acaattacaa aatatgattc aggttctttg tgcaagagct tttatgaagt
     3061 ttataaattc caaagatgaa gatagtgaat ctatagtagt agtagatata aatgaagttt
     3121 taaagcttaa agattctttt aaagatgctg cctttcaaga gattgaatat acagagataa
     3181 gaaaatattt gaaaaatgct atatttatac catttaattt agaagaatca tcagtaaaag
     3241 gaagtctttt aagtgatgaa tatatattac cagaggacat atacaaaaca attgaaaaga
     3301 aatattatga cctaaaatcc ctagacattg aagatataga tatagagaat attttatgga
     3361 cttttatttt aaatagattt gctgacttaa agtttaatct tgatagtaat gaagaaattt
     3421 tttcaatgag tgatttaaat agttttgtaa gtgatagttt agttaaactg gtaaaagaac
     3481 ttatgaatga tatagttgaa aaaaatatga atttagaagt aaataaaaat atgttcaaat
     3541 atctagcaat acacttagaa gaagctataa aaagaattaa gctaaatcaa aagataataa
     3601 atgtaaattt agaaaaaata aagattgact tttcaaaaga atataaaatt agtaaaagtt
     3661 ttgcaataaa aattgaggaa tcaattggta ttaagatttc agatgatgaa attggattta
     3721 taacgctcta cataaagtct gctctaaaaa atgaagtgaa aaaagataaa gtagggttaa
     3781 taataatttc tcatggacgt atagctacag aaactgtaaa tgtagttaaa gaacttttag
     3841 gtgtaaagtt tcctgtggct atagatatgc ctttagatga aaaaccaata aatatataca
     3901 ataaggcagt agaactgtca aaaataatag accaagggaa aggcatattg tttttggtgg
     3961 atattggttc acttacaaac ataggtcaaa tagtaaataa gagaaccaat ataagtacta
     4021 aaactattga tagagtagac ctcctaatgg cactagaagc aactagaaaa gtttctatgg
     4081 gagaggaaga acttgatgaa atattttttt ctttgctaaa agataggatg ggatataact
     4141 atgaattaga aaaacacata gataaatcaa atgcaattat aacattatgt cttactggag
     4201 aaggaactgc taagtatata agtaaaacgt tggaagaaaa gtatgataac actaaatgtt
     4261 atcaaatgag tgcattggat gaaaatttat tttgtaaaat tgaaaatcta aaagagacaa
     4321 acaatatatt agctattgtt gggacaataa accctaagat accaggtata aattttatac
     4381 cctataataa agaacttttc aaaaatttgg atatctatct atcaaaatca aaacaacaag
     4441 atgacagacc aattaaatcg tatgaaagaa tgcttgatga ggatttagtg atttttgaac
     4501 cagatatata ttttaaaaag gatttattag aatatgtatg ttcaattctt ataaataaag
     4561 aatatgtaga aaaagattac ttagattctg ttttacatag agaagaaatg cttccaacat
     4621 attctaaagg agctataggt gtgcctcatg gagattcttc tactgtaaat agtacaaggt
     4681 ttgtttttgt taaactaaag aatcctattg attggggtgt aggtaatgta aatttcatat
     4741 ttatgccagt ttttcaggct aatgataaag agattgttaa aaatgttctt gagatactaa
     4801 aagatgcaga atttatgaac aatgccaata agtgttttga taaagatgct tttagaagga
     4861 ttatatttga taaatttaaa catctgtagc catagcaaaa aaattgagag gagttagagt
     4921 aatgaatgta gatttaatat cattgggttt agaatctaat gattatgaaa gtgttattga
     4981 agaattagga agtataatgt gtaaaaaaga atatgtaaaa gaaacataca taaatgctgt
     5041 cttggaaaga gaaaggacat taccaacagg tctagatatt ggagaaatgt gtgttgctat
     5101 tccacataca gattcaaagc atgtaaatga gtctaatgta gctgtaggga tattgaaaaa
     5161 tcctgtaaag tttaattcaa tgatagaccc aaaagataga cttgatgtag aacttgtatt
     5221 tttattagca gtaaagaacc cagactcaca agtaaaactg ttaaaagatt taatgtcagt
     5281 ttttcaaaat ataaagttat taaaaaatat aaaaaacgca tcaacaaaag aagaagtagc
     5341 taaattattg gactttatag aaatttaatg taggagaatt ttataaataa aaaattaaaa
     5401 tttaaacaat caaagtaagt attatttttt taataggttt aatcttatat aaaataaaaa
     5461 tttagagtga aaaactagga ggaaattatt atgaaacaat ttaatgtatt atcagtttgt
     5521 ggttcaggga cagttacatc atctatggta gcaggtaaat taaaagaagt actaggtaat
     5581 aaggggattt ctattactac aacagaagct agaccaacag aagcactaaa tttagcacaa
     5641 tcaggaagat ttgactttat aacatttacg agtccacttc aaacaggcga ttatggaata
     5701 ccaactataa atgcatttgc ttgcctaact ggtatagggg aagaggcatt ctttgaagaa
     5761 gttttgactg ttattgaagg gatagataag taagttttgg agacgtgaat ttatagtatt
     5821 taaatcaatg atttagatac tataataagc taatattaac taaatatttg tggaaaaaac
     5881 attttatatg ttgtcataaa ttaaaaaatt ataaaaatag tcacttaagt attaaattaa
     5941 gcttataaat atttataagt aggagggaaa aagatgttag aatttatgaa atctataatc
     6001 gatacatttg gttctgcaat tatagttcca attataatat tcataatagc aaagatattt
     6061 aaagtaacta ctaagaaatc gtttctttct gctgtgtatg caggagttgc tttacaaggt
     6121 tttacactga ttttaaattc atttacacca ataataacac cagttatcaa taggatggtt
     6181 gagagtacag gagtaaacct accagttttt gatgttggtt ggcaagcaac atcattagtt
     6241 gcattttcaa caagtgcagg tatgatatat ttaggtcttg gtatattatt acaaacaatt
     6301 ttatttttga taaaatggac agacgtgttt caaccatcag atttatggaa taactattct
     6361 tatatggtat ggggagcaat ggttatagga gtaacaggaa attttccttt aggtatagca
     6421 tgtatggttt tattaaacct atatagttta ttaatatcag agttagttgc aaagagatgg
     6481 tctagttact atagatatcc taattgtaca ataatagcta tgcataatgt tgaggcttct
     6541 gtgtttgcag tatttgcaga ccctatatac aataaattgg gattaaataa aataaaatta
     6601 aatccaaaag aattagagaa gaaattaggg tttttaggtg aaccaattac cttaggtctt
     6661 tttttaggta tgtttatagg tatattaggt aatatgacga gaataaatac tatggaagct
     6721 tggggagaaa taatgaaagt aggtatatct acaagtgcag tgatggcaat tttccctaaa
     6781 gtagcaagta tgtttgctca agcatttgca cctataacag aagcagccag aaagattatg
     6841 caaaaagctg gaaaccgtga gtggtacata gcagtaaatg atgctgttgg atatggtgaa
     6901 cctgcaactt taatatcagg tcttatatta attccaataa tgcttgtaat agctatggta
     6961 cttcctggta ataaggtatt accagttgtg gatttattgg caattccata tatggttcaa
     7021 ggtttagttg ccatacataa tggtaatata ccaaaagtat tagtttcagg tataatttgg
     7081 tttggattag gattatatgt ttgtacatct acagcaccat tatttacaga tatggctaca
     7141 aatataggtg tagctatacc tgcaggagca atgttaataa caagctttaa tatactagga
     7201 aaacatttga tggggttagt tttctttgca tttctaagtg caaatccaat ttatataggt
     7261 ctttcagttg taatttactt tgttctatgg gcattgttta gaaagaacaa aacaagtatt
     7321 cttgattatt tagaaaaaca agcacttaaa aatgtagaag aagagcctgt agcagtttaa
     7381 gtttataaaa atgaaataaa aataattaaa ggagtttata attgatttta tataagtatc
     7441 agataatacc tgagaaatat ttaaatgaaa tatagacttc tttttatttg ataatatttg
     7501 taattataat gcattgtatc tttatagttg agttttctgt ataacctgct atttaaaaca
     7561 tactctttta tatttataca gtaatgtggt ttaattttat aaaatgtaat ctctactggt
     7621 aaaagacttt gtatataagg catttgcctg aataaaccat ttatcttttg tatggcatag
     7681 atattgctat atagaagtat atagcatgaa aggagatatt tatatgggaa ataaaatgag
     7741 agcatcagta ttgtataatg taggtgatgt cagatatgaa atggtagata taccagaaat
     7801 aacagatacg caagtgcttg taaatgtaaa atatgttggg atatgtggtt cagatttacc
     7861 taggtctatg gtaagtggtt tgagtggaaa tacaaaatat ccattgattt tagggcatga
     7921 attttctggt gaagttgtta aaattggaga aaaagtaaag catattaatg taggagatag
     7981 agtagctgtt gcaccattag taccttgtgg aaaatgtgat tattgtaatg aaggtaattt
     8041 tggcttgtgt gatgattaca atataattgg aacaagagta aatggagcgt ttgcagaata
     8101 tgtaagagtt ccagaagaac atattttaaa actaccagat acattggatt atgaaactgc
     8161 tgccggaatt gaaccagcaa ctatagctta tcatgggatt tcaaagtcta atattagagt
     8221 aggagatagt gtagttgtgt taggatgtgg tccaataggt cagtttgtta tacaatgggc
     8281 aaaggtgttt ggtgcatcta agattatagc agttgatatt tttgatgaaa aattagaact
     8341 ttctaaactt ctaggagcaa actatatact taactcaaaa gaagtaaatg taatcaaaga
     8401 aataaaaaaa ataacaaatg gtggtgctga tgttgtaata gagactgctg gtagccgatt
     8461 tacacaagaa caatctctat ttgtagcaaa aaagagagga aatatagtgt ttgtaggtat
     8521 atcacacaca gaattaccac ttagtgcaga cgctactgag tgtatattac gtggagaact
     8581 taccttgaaa ggttcttgga attcatatac aagcccttat cctggaagag catggactgc
     8641 aacattggat tttatgggaa aaggtgacat tatttttaaa cccatgattt cacataaaat
     8701 aggtcttaat gaagtgggtg actttttaag taaaatgagc aagagagaaa ttaatttcaa
     8761 taaaatccta gtagaaatat aaaaatttaa taaaaaattc taaaagcaat taaattttat
     8821 aactatgaca ttaaataaaa taaaaataat tttcttaaat aaaatatagg aggaagaaaa
     8881 gtgttagaaa atttaaaaga agaagtatta aaagcaaact tagaattacc taagaaaaag
     8941 ctaattactt atacttgggg aaatgtaagt gggatagata gagaaaaagg attagtggtg
     9001 ataaaaccaa gtggtgtaga gtatagtaat atgactgtag aagatatggt tgtagttgat
     9061 ttagagggaa atatagttga tggcaaatta agaccttctt cagatactcc gactcatcta
     9121 gttttatata aagagtttga agaattgggg ggaatagtac atacacattc aagttgggca
     9181 acaatttggg ctcaaatagg aaaatctata ccatcttgtg gtactactca tgcagattat
     9241 ttttatggaa gtataccatg taccagaaaa atgactagag aagaaatttg caatgaatac
     9301 gaaaaggaaa ctggaaatgt aatcattgaa gaatttatgg gaagaaatcc aattcattgt
     9361 ccaggaataa ttgtaaatga ccatggacct tttacatggg gaaaagatgc aaatgaggct
     9421 gtacacaatg cagtagtttt agaagaagtc gcaaagatgg cttattatac agagttaatg
     9481 agtcctgata atattatgga taaggttctt atgaataagc atttttcaag aaaacatgga
     9541 aaaaatgcat actatggtca aaaatgatta tctggaggtg aattatgcta gactctttaa
     9601 aaggtaaagt tgtggaaata gcaattaaag cagagcatta tggtttatgt aaagaaaaga
     9661 ctggtaattt tagtattaga gataaggata ctggatatat acttataacc ccatcaggtg
     9721 taggaagaga agaattaaaa gttgaacata tttgtgtatt ggatttggat ggaaatgtaa
     9781 tagaagttga gaaaggtatt aagccaagta gtgaggtatt gatgcatatt gaaatataca
     9841 aaacaagaga aaatataaat gccatatcac atactcattc tttatatgca acagcatttt
     9901 cagtagcaaa gaaagcaatt ataccaattg tatatgaatc agttaattat ggcggttatg
     9961 tagatattgc ttcatacgaa agaccaggaa ctttaaaatt agctaagagt gtttcaaaat
    10021 tactgataga tacagatgca tgcttattag aaagacatgg gttgacaact gtaggtaatg
    10081 atttagacga agcattatta aaatcaagat atgtggaaga ggtagcagaa atatactata
    10141 ggtctttagt attaaatcaa tttaaagaac ttgaagtagt agatgttgat gagtttaaat
    10201 cttggaaata cccagaagaa ataaagtttt aatctaaata attttcattg aagtggttaa
    10261 ttaaaatata tgtattattt atatcaatta ctatgtttta ttatgttaat taccgtattt
    10321 tgcaaatata tttattacat tttttcaaaa aaatatagaa tccgaaagcc atataaaatt
    10381 gacttgggat tctatacttt ttatttatgc atttttcttt atctgatttt ctggagaatt
    10441 tatatgttca aaatattttt tagtttcaga tactattata ggtgataatg caagtaaagc
    10501 tataaggtta ggtattgcca taagcccatt tacaatatca gcaattatcc aaacaacttc
    10561 taactttaag aaagcaccta ataacaccat agccacaaat acagttctat acccattcat
    10621 gccttttaca ccaaacagaa attcaaaaca tctttctcca taataactcc atcccaaaat
    10681 tgtagtaaat gcaaataatg ttaaactaac tgtaagtaat attggtccaa atgtaggaat
    10741 tgctccgtta aaagctgctt gtgtcataac agctccattt aggtctgaac accacactcc
    10801 tgaaataaca agagagaatc cagtaagagt acagattata atagtatcta taaaagtacc
    10861 tgtcatagat ataagacctt gttccgctgg ccattcagtt ttagcagcag cagcagctat
    10921 tggagcacta cctagaccag actcatttga aaatacacca cgagcgatac catttctaat
    10981 tgctagtgac atagttgctc ctaaaaaacc accagtagca gcagtaggtg taaatgcact
    11041 tttaattatt aacataaaag tttcagggat tttattccaa aaagatatta aaatgattcc
    11101 acagattaca acatatataa ctgccataaa aggtactatt ttagtagcta cattagatat
    11161 acttttaagt cctccaaata caaccaaagc tacaaatact gctaatacaa cccctgtaat
    11221 tctagggtct atcccgaaac tattatttat tgcatctgtt attgaattta cttgagtaaa
    11281 agtaccaatt cctaaaagtg caactagtat accacttata gcgaaaaata ttgcaagagg
    11341 tctccatttt tctcccatac catttactat gtaatacatt ggcccaccag acacttggcc
    11401 atttttatct ttagttctgt attttattgc aagaacacct tctgaatact tagtagccat
    11461 tccaaagaat gctgctatcc acatccaaaa aagtgcacca ggtccaccag ctttgatagc
    11521 tgtagcaaca ccaacaatat taccagtacc aactgtagca gctagagcag tacataaggc
    11581 tgcaaaactt gaaacatcac cactaccttt gttttcagca gagaatatta acttaagagc
    11641 tcttggcagt ttagttattt gaacaactcc aagcttaaca gtaagtagta taccagtacc
    11701 aactaatagt accagtaggg gtggtcccca aataaaagca tcaactttgt ttaaaatatc
    11761 aattagattc ataaaaacac tccctcattt tttttgcttt acataatcaa tagaattttt
    11821 aatgaagtaa ttgacaggaa ataagtataa tttattaata atttctagtg taataaaaaa
    11881 agctaaatct aaaaaagatt cagctctgga tgtacactaa ttagcaacca aaataaaagt
    11941 attagtaaat actgtttttg gtagataatc cctgtccttt tgcctgagag attgagcata
    12001 aaagccttgc cccttcggcg cccataatgg gtctctccag agttccgtaa attttacagt
    12061 cctactttta aaagtacctg agagtgttac tccttcggtg tgctatatag caactcttct
    12121 ataaaatctt aaccggatat tgatttgtca tagcttattg tattaataat attaatataa
    12181 gtttttatgt tttgtcaact aaaaaattaa aaaacaaaga aaaaatataa aaatgtaagc
    12241 ctatttacga attataaact tagaaagatg agtaatatac gtgaaaatga attttgtaat
    12301 acacatacaa atgaagtgta aaataagttt taaataaaaa aataataaaa tcttaaataa
    12361 ttaattagat atgattaaat tatggtaata ttatagttac gatattaaga aaagttctat
    12421 ttagttagat tttaagcgta atatgagatt atgtatagag aaaggatgta tttttagatg
    12481 ggaaaaatat tagtgctagc agagaaacct tctgttggaa gagatatagc aaaagtttta
    12541 gggtcaaaaa atgaaaaaaa tggttatata gaggggccga agtatgtgat aacttgggca
    12601 ctaggtcatt tggttacact tgctgacccc gaaagttatg gagaaagata taaatcatgg
    12661 agcttagaag acctgccaat acttcctaag taccttaaga ctgttgtaat aaaaaagagt
    12721 ggaaagcagt ttaatacagt taaatcgcaa atgaatagaa atgatataga tgaaatagtt
    12781 atagcaacag atgcaggtcg tgaaggagaa cttgtagcaa ggtggataat agaaaaatca
    12841 caggtaaaaa aacctataaa acgtctttgg atttcttcaa gtacagacaa agcaataaaa
    12901 gacggatttg caaaattaag aagtggaaaa gaatatgaaa atttgtatta ctcagcaata
    12961 gcacgagcag aagctgattg gattattgga ataaatgcaa ccagagcttt gacaacaaag
    13021 tacaatgcac agctttcttg tggaagagta caaactccta ctcttgcaat gttgcttaaa
    13081 agagaagaag aaataagaaa tttcaaacct aaagagtatt atggattaga attaattgct
    13141 acaaagggaa attcagatat aaaatttatt tggaatgata aaaacaataa ttcttcaact
    13201 tttagtaaag aaaagataga atccacatta aaaaaagtaa aaggtgtaga cataaaaata
    13261 tctgaagtaa acaagtcata taagaaaaaa tattcacctg cactctatga tttaacagaa
    13321 ttacaaagag atgcaaataa aatgtttgga ttttcagcaa aagaaacttt atctataatg
    13381 caaaaactgt atgaacatca taaagtactt acttatccta gaactgattc tagatattta
    13441 acatcagata ttgttggaac attaaaagat agaataaaag ctgtaaatat tagtgattat
    13501 tcaaagactt gtaataaatt attaaaaagc aatattatag ctaataaatc gtttgttgac
    13561 aattcaaagg taacagacca tcatgcaata ataccaacag aacagaaggt attcatgagt
    13621 gattttagtg acaaagagcg aaaaatatat aatcttgtag taaaaagatt tttagcagta
    13681 ctatctcctc cttttgaata tgagcagaca actataagtg caactgtaga aggagaaata
    13741 tttaaggcta agggaaacaa agtaataaat ttaggttgga aagaaagtta taaagatatt
    13801 gaagatgaag atgagtatga aagtatacca aatgttttag aaaaagatgt acttaaggtc
    13861 aagggattaa agataacttc aggaaaaaca aatccaccac catacttaaa tgagggaaca
    13921 ttattgactg ctatggaaaa gaatggtcta gggacagttg ctacaagagc agatataata
    13981 gaaaaattat tcaattcatt tttaatggaa aagaaaaata aagatatata tataacatca
    14041 aaaggaagac aattattaga tttagttcca gtagacttaa agacaccaga acttacagct
    14101 tcatgggaaa agaaattatt ggatatttca aagggaaaac ttagtaaaaa tacattcata
    14161 aatgacatga aagattattc aaaagatatt gtactagaag taaaaaatag tgataataaa
    14221 tttaaacatg ataacttaac taaaaataga tgtccagaat gtggaaaatt tatgttagag
    14281 gtaaatggta aaaaaggtaa gatgttgatt tgtgaagata gagaatgtaa tactagaaaa
    14341 actatatcac aagtaaccaa ttcaagatgt cctaactgtc ataaaaaatt agaacttcgt
    14401 ggagaaggtg aggggagaat cttcacttgt agttgcggat acagagaaaa gttgtcttct
    14461 ttcaacaaga gaaagcaaga agaaaaacag aaggcatcaa aaaaagatgt taatcaatat
    14521 ttaaaaaatc aaaataaaaa tcaagagaca tttaataatc catttgcaga agcattagct
    14581 aagctaaaaa acaaataatt ttaaagttat tattatacac aattataact ttaactgtat
    14641 attagttata tgtactgata taatatagtg tatagtttag gcatgaaagt agggctgtta
    14701 aatggattta agtggcatat ttaaatacta ttgtaaagag tgtgaaaata catggaataa
    14761 ttcgagtgtt gaattatttg agaatataga aacgtatagt aaagattcac aaaaaaagag
    14821 ggaaaaagaa ttagataaat tgctaaatac aatatcagtt catttagaga ggtatccaag
    14881 tgatgctgta ttgagaaaaa tgtgggtaaa aaagggcgag gttttcttac aaaagacatt
    14941 ggaaaaagaa aatattttta agttagaaaa aatggatgta gaggatagaa aaaaattttt
    15001 agatataaca aaacagttta ttagagatgc tagaaaattt gatgatgatt tacctatagg
    15061 tgatattatg caagctatga ggaatgtatg gatttcaaat gcattacaat tattatttgg
    15121 taaagaagta tattattcaa aagctaactt tgcatatagt atgttatatc catatactga
    15181 taattattta gacaatacaa atatagataa aaatgataag attttattta ataactggtt
    15241 agaaaaaagg ctcctgggag aacacattaa atctaaggat tatcatgaaa gtaaagtatc
    15301 tcaaatgata gattatattg aaagtgtata ccctagagaa aagtttacag aagtttatga
    15361 atcgttatta ttaatattta aaagtcaagt aaatagttta aaacaacatg gtaaggaaaa
    15421 tcatttgtgt aaagaagatt tattatccat ttctattgaa aaaggaggtt catccgtttt
    15481 agtagatgga tatttaataa gtggattgat gacaaaggaa gaaatagagt tttgtatagg
    15541 atatggattt ttattacaaa tatctgatga tttacaagat ataaaagaag atttaaaata
    15601 caaccataaa actattatta cagagatgtc aaaagagggt actttagata aagttgtaaa
    15661 taaactaata aattttacta ttgagttaat agatagtttt aaaattaata ataaaaataa
    15721 atctgtaata actatgataa agaatgattg cttaatgtta attttatttt ctgtagttta
    15781 taatgctgaa tttttttctg taggatatat aaaagaagta gagaaattta ttccatatac
    15841 aatagactat tcattagaga ttgaagaaaa aataaaagaa aaatttaaaa atatagatgt
    15901 tttaaataat gaaaatgaat ataaagaaat gattgatatt atttgtgcag agtagaaaaa
    15961 aagggagtgt cttagaatag actttttagt ttatgaggca ctctttttgt ataaaatcaa
    16021 atgtattttc atcattttaa caattaaaaa gagcttatcc ctatttgaga aagccctttt
    16081 taatttaaat aaaaatgtca aggttaaact acttaaatgc agtaataatc ccattatcat
    16141 gtaagttttt tatgattgta gctgcgatag ggaatccaaa taatccagct attccaaata
    16201 gttgagctcc aacaaacata cacattaatg ttattaaagg atataggcca atttggtgtc
    16261 ctactacctt tggttctaat atttgtctaa caacggttat aattatgtat agtattaaaa
    16321 gtcctattgc taaattaata tttccattaa tgagtgagat aatcatccaa ggtgtcaaaa
    16381 tacttcctgt acccaagact ggcaaaatat caacaagtgc tatgatgaca gatatagtaa
    16441 atgcattttc aacctttagg atagtaagtc caataagtag ttctatgaat gtcactgata
    16501 gtagtattgc ataggctttt agtagtttta aaagagcatt aatactgcta ttttttatat
    16561 ttattatcat aaattgactt ttttctggaa attgttttaa gataaagttt actatttttt
    16621 gatagtcaaa agtaaagaaa aaagaagcaa ttaaagtaat aataagtttt aacataaatg
    16681 caggtgtttt acttgcaata ctagcaatag cattgagtgc atttgtggaa atagaagcta
    16741 ctaaagacat catagattga cttatattat cccaaccaag tattaatgct aggttaacat
    16801 taggtgtact agcatctatc tttgaaaata aagcatttag cgttggttgt atacttgatt
    16861 tatatatttc aggaagtcta aaaaatacat cacttacact tgcaaatatc ttcacaccaa
    16921 agctaactaa taaaaatata cacaacccat aaaaaattaa aagtattact atagaaataa
    16981 gtgtacgatt taaatttgta ttatttgtaa taagtcttat aataggtctt aagatggatg
    17041 caatgataaa actgattaca aaaggcatta ataatggcaa taagaatttt aatacaatat
    17101 atacaatact tgttattaaa actacatatg taaatttaat tataaaattc ttttgctttt
    17161 gaatatccat aatataaaac ctccaatgta tttgatatta ttctaaatat ggtctttttt
    17221 acagaaaata tactactgta tattgattat aaactataaa gcttatgtaa agtaaataaa
    17281 ttatgtaaaa tttaggttaa ttttgtataa agagatactt ttatatttta caattaataa
    17341 ccaaatacta aaaaatattt taaataaaga acttaaaatt gtgataaaat taatttatag
    17401 atattaaaaa aagtataata tatggttttt aagaggtgct aagatgaaaa attttagaga
    17461 tttaggtggg aacaaaactg aggatggaag aactgtaaag aagggattat tttataggtc
    17521 tgcaaaatta tcaaatctaa gtgaaaatga tataaagatt ttaaaagagt taaatattaa
    17581 atatatattt gattatagaa gtgatgaaga agctcgtaaa catccatcaa caataatatc
    17641 aaatataaaa aatataagaa taccagcaat gagagagcta gaagaatcag gaggaagttt
    17701 tggttctatt gaagatatga ttgatggatt gtttgaaaaa gatggtgcat ttaatatgtt
    17761 aaataatagt tactataatt tgcctataaa taatccgtca tataaaaaat tagtagaact
    17821 tataagagac tattccaatt taccaatatt aaatcattgt acagctggta aggatagaac
    17881 tggtgtgggg agtgctataa ttcttatgat tttaggggta tcgagagaga atataatgaa
    17941 agattatcta aaaagtaatg attttgcaga taaagagata gaaagattta tagaatataa
    18001 gcctaaattt aaggacattc caaaagaaaa tttaaaatat atatttggtg taaatgaaga
    18061 gtatatgaaa actgcattta gaagaattga tgaagaatac attagtgtag aagcatattt
    18121 atatggagaa tttaatttaa ataaagaaga aataagaaaa ttaagaaatc aatatctaga
    18181 gtaaaaggtg agtttatgag tttaaatata acagcaagac agataaatat aataaaaata
    18241 ttgttaaatt caaaagatac aattagtggt attgccttaa gtcaagagat aggatgttct
    18301 tcaaaaacta tacaaaatga aataaaggat attaataaac aacttagaaa tggtaaaatt
    18361 ttgtcaataa gaggagttgg ttataaacta gaaggaagtt ttgatgaggt aaatctaaat
    18421 agcaatctct atgatgatgt agatagagta gaatatataa tcagaaaaat attaacctta
    18481 agtaatgaag aaaaaaatac tataaaactt gaagatttag ccgattctat gtatgtaagt
    18541 gtatcaacag taaaaaatga tttaaaagaa gtaaaaagaa tattggaaaa gtattcaata
    18601 tcagttaaat ctaagcataa acaaggtata tgtgttttgg aaagtgaaga taagatatta
    18661 aattgtatag ttgacttaag caataagaga gataatcaat tgagtttaaa tgatttttta
    18721 aatgatgata taaaggaaag aaaactatta ataaaaaaat tattattaga catattaaat
    18781 gaaaatggat tagtattaac tgatatagaa tttaagagtg tgttaaataa tatattagtt
    18841 atgttaagca gacataagta taatgaaaaa gaatttatag agaattatat agaaaattat
    18901 aggagcaaaa gaagctcaat tttagaaaat gaacaaaaca aagaaattat aataaattca
    18961 ataaaaacat tttgtaaaaa tttaaaatta gctacatcaa tagatataag taatgataag
    19021 gtatttgaag agtttttata taagcatatt agtagtttat gtaaaaaaat aaagttaggt
    19081 ataaatcaat cacctataat ggctcaagat ataaaaataa aatatccatt tgcttttgaa
    19141 ctagctaata tagctaaaaa gacaatagaa aaagatttga agatagaaat taatgaagat
    19201 gaagttgcaa acatagctct acatatagga ggagcagttg aaagagcatc ttataataat
    19261 aaagataagg ttttcaaaac tataatagtt tgtacttcag gcataggcac atcaatgtta
    19321 ataaaagcta aattagagaa tatatttaag gaaaaattag aaatactaaa gattattcct
    19381 tcatacttag ttgaatatat aaaagttata gatgttgatt ttgtaatatc tactgttcct
    19441 attgaagtag gagatgtgcc agtaataaat atatctccaa ttttaagtga gaaagaaatt
    19501 agattaattg aaaaatatat agaaacagga aatatatacc tagatttaga tataaaaagc
    19561 ctgtttgata gtgaattatt ttttactgat ttggtgttta aaaggaaaga agaagttata
    19621 gattttatgg caagtaaact tgtacaaaag ggctatatag atgaggatat gaaaaaatct
    19681 tactttgaga gagaaaaaat agcaacaaca gaaataggga atatggtaac tataccacat
    19741 ggagctattg ggaaaatttt tgataataaa atagcaattg gtatattaaa gaagcctatt
    19801 tcttgggaaa tatcagatgt tcgtttaata ataatgttag cccttgataa agataaaata
    19861 ttagattatg aagtaatatt ttcaaaaata tataaaagag tagattctat agcaaaagtt
    19921 ataagtatat gtgaaaatag tagttttgaa aaatttgtaa atttatttaa ttagatgggt
    19981 agtattgtat atacacctgt aaatttggat aatataaaac taaataagat aaaaacgata
    20041 aatttctctt ttaattaaga gaaatttttt gactttcaag gatattaata taaagttaag
    20101 atataaacat aaagcaaata aataaaaaag aggtggcaat atgatttata cagtgacatt
    20161 aaatccatca atagattata tagttaagct agatgagcta aagacaggaa gtacaaatcg
    20221 tgtaaaagaa gaatacgttt atccaggagg aaaaggtata aatgtatctc gcatacttaa
    20281 ggaacttgga aatgataata catctttagg ttttataagt ggttttactg gagaatatat
    20341 aataagaaca ttggaagaaa aagaattgaa gacagatttt ataaagataa aaagtggttt
    20401 ttcaagaata aatgtaaaaa taaaggcgtt aaaggaaact gagattaatg gacaaggtcc
    20461 aaatatagat gatgaagaca ttgatacttt atataaaaaa cttgataagc taaatcaaga
    20521 tgatatttta atattggcag gaagtatacc atctacttta gatgaaaaac tatacgaaaa
    20581 tataatggct agattagaaa aaaagaatat aaaagttgta gtagatgcaa ctaaaaatct
    20641 tcttcttaat gttttaaaat acaaaccttt tctaattaag cctaataacg acgaattaga
    20701 agaactattt ggtgttaaat taaattcaat tgaagacatg gtaaaatatg ctagaaggtt
    20761 aaaggaaatg ggagctataa atgtcttggt atcaatggga aaagatggag cattgttgat
    20821 tacagaggaa gatgaagtgc ttataagtga tgttccaaaa ggaaaagtaa aaaattctgt
    20881 aggagcaggt gattcaatgg tagcaggatt tatatctggg tatttgaata ctgggaaata
    20941 tgattatgct cttaaattgg gagcagcttc aggtagtgca actgcttttt catatgactt
    21001 agccaaaaga gaatacattg ataaattggt aaatgaaata tctgtaaagc agttttaaaa
    21061 tattaaaaaa tatatagaaa ggtaattaat atttatgaaa attatagatt tattagatga
    21121 aaagtcaatt aagttaaatt taaattcaaa aaccaaatca gaagcaatag aagaattagt
    21181 agatttggtc gcaaatagtg gaaatttaaa tgataaagaa aactacaaaa aagcaatttt
    21241 ggctcgtgaa gaaatgagta caacaggaat tggagaaggt gtagctatac ctcatgctaa
    21301 aaattcttca gttactaaag cttgtatagc agcagcagtg tcaaaagaag gtatagatta
    21361 tgaatcgttt gacggaagtt tatcaaatct attttttatg atagctgcac cagacggagc
    21421 taacaatact catcttgaag tattatcaag attatctaca atacttatgg atgaagactt
    21481 tagaaataaa cttataaatt caagctctga aaaagaattt aaggaaataa tagataaaaa
    21541 ggaaagagaa aaattcagtg aagaatatca agatgagaaa gttgctgaaa aaaatataat
    21601 agatactaaa gagaatgatg ctaataagta tcctaaggtt ttagcagtaa cagcatgtcc
    21661 aactggaata gcacatacat ttatggcagc tgaaagttta aataaaatgg cagaaaacaa
    21721 aggtgtatca ataaaagtag aaactaatgg ttcagcaggt gttaaaaata agcttacaaa
    21781 agatgaaata gaaaatgcaa catgtataat agtggcagca gataaaaatg ttgagatggc
    21841 tagatttaat ggcaaaaaag tcataaaaac taaggtggct gatggtatac acaaagcgga
    21901 agaacttata gacaaggctg taaatggaga tgctccaatt taccatggag gagatggaag
    21961 tcacaacgaa tcaaatgaag aaagtgaaag tggatttaga aaagtataca aacacttaat
    22021 gaatggtgta tctaatatgt taccatttgt tattggtgga gggatactta tagcgatagc
    22081 ctttttactt gatgattata ctattaaccc ttcaaacttt ggttcaaata cacctatagc
    22141 agcatttttt aaaggaatag gagataaagc ttttggattt atgttacctg tacttgctgg
    22201 atatatagca tactctatat ctgatagacc agcgtttgtt gtaggatttg taggaggtgc
    22261 tctagcaggt gatggtggtt caggcttttt aggtgcacta cttgcaggtt ttatagcagg
    22321 ttatttagta gaagggctta agaaaatatt tagtgtacta ccagcttcat tggaaggaat
    22381 aaaaccagta ttgttatatc ctttacttgg aacacttttg atgggaatta taatgacatt
    22441 tttagtaata cctccagtta cagcaattaa taatgcaatg gttggatttt taaatggttt
    22501 aggtggaact tcaaaaatag ttttaggatt agtattaggt ggaatgatgg ctgtggatat
    22561 gggtggacct gtaaataaag cagcatatgt atttggagtt gcatcacttg aatcagggca
    22621 gtttgaaata atggcagcag taatggctgg tggtatggtt ccgccacttg ctatagctct
    22681 tgcaactaca ttttttaaga atagatttac taaagaagaa agagattctg gtaaagttaa
    22741 ttatgtaatg ggattatcat ttgttactga aggagctata ccttttgcag ctggagaccc
    22801 acttcatgtt ataccagctt gtgttggagg ttcagcagtg gcaggagcac ttagtatgtt
    22861 gttcaacgca gctcttcgtg cacctcatgg aggagtattt gttataccag tggttaccca
    22921 tccatttgca tatatattag ctatagctgt aggtgctttg gttggaatga tgcttttagc
    22981 attacttaaa aaaccattaa atcaagaagt atagcaatta aaggatattc aagaacttaa
    23041 aatatgatgt tttataaaaa ttaatatatt gctgaattat tttaaaataa ggattttatg
    23101 aggctgttat ataacgattt gtaattgtta tcttgacagt cttttatttt tatataagta
    23161 aaataagtgt gttttgcttt atttgtattt aaattgtttt caagttagaa cataaagaaa
    23221 attatatatt attttaatat tcactcgaac tataaaataa tatttgttgt attt
//
LOCUS       DAEPUT010000064        22766 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.066, whole genome shotgun sequence.
ACCESSION   DAEPUT010000064 DAEPUT010000000
VERSION     DAEPUT010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22766
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.066"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..249
                     /locus_tag="KRL22_002663"
     CDS             <1..249
                     /locus_tag="KRL22_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1273135.1"
                     /translation="EEDEFVQAAYKGLKEAGIDSEITQYSFCTNGSHYAGEAGIRTIG
                     FGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSVYKK"
     gene            265..1848
                     /locus_tag="KRL22_002664"
     CDS             265..1848
                     /locus_tag="KRL22_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBH1273136.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCNVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKNLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            1876..3204
                     /gene="ssnA"
                     /locus_tag="KRL22_002665"
     CDS             1876..3204
                     /gene="ssnA"
                     /locus_tag="KRL22_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBH1273137.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            3349..4701
                     /locus_tag="KRL22_002666"
     CDS             3349..4701
                     /locus_tag="KRL22_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH1273138.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     TAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            4893..6002
                     /locus_tag="KRL22_002667"
     CDS             4893..6002
                     /locus_tag="KRL22_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1273139.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            6285..7676
                     /gene="hydA"
                     /locus_tag="KRL22_002668"
     CDS             6285..7676
                     /gene="hydA"
                     /locus_tag="KRL22_002668"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH1273140.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            7670..10231
                     /gene="xdh"
                     /locus_tag="KRL22_002669"
     CDS             7670..10231
                     /gene="xdh"
                     /locus_tag="KRL22_002669"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HBH1273141.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSIPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            10383..11729
                     /gene="rpoN"
                     /locus_tag="KRL22_002670"
     CDS             10383..11729
                     /gene="rpoN"
                     /locus_tag="KRL22_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBH1273142.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            12511..13533
                     /locus_tag="KRL22_002671"
     CDS             12511..13533
                     /locus_tag="KRL22_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1273143.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            13593..14600
                     /gene="gap"
                     /locus_tag="KRL22_002672"
     CDS             13593..14600
                     /gene="gap"
                     /locus_tag="KRL22_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH1273144.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            14822..16024
                     /locus_tag="KRL22_002673"
     CDS             14822..16024
                     /locus_tag="KRL22_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBH1273145.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            16050..16793
                     /locus_tag="KRL22_002674"
     CDS             16050..16793
                     /locus_tag="KRL22_002674"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBH1273146.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTDIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            16802..18334
                     /locus_tag="KRL22_002675"
     CDS             16802..18334
                     /locus_tag="KRL22_002675"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBH1273147.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGRLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
     gene            18922..20214
                     /gene="eno"
                     /locus_tag="KRL22_002676"
     CDS             18922..20214
                     /gene="eno"
                     /locus_tag="KRL22_002676"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBH1273148.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            20819..21043
                     /gene="secG"
                     /locus_tag="KRL22_002677"
     CDS             20819..21043
                     /gene="secG"
                     /locus_tag="KRL22_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBH1273149.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(21427..22365)
                     /locus_tag="KRL22_002678"
     CDS             complement(21427..22365)
                     /locus_tag="KRL22_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH1273150.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFRLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSILTVFLIIFILKQNNLI"
     gene            complement(22353..22751)
                     /locus_tag="KRL22_002679"
     CDS             complement(22353..22751)
                     /locus_tag="KRL22_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1273151.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNVK
                     INLNIKGYKFLPYVKNSKASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
BASE COUNT         9061 a         2606 c         4399 g         6700 t
ORIGIN      
        1 gaagaagatg aatttgttca agcagcgtat aagggattaa aagaagctgg aatagattca
       61 gaaataactc aatactcatt ctgtacgaat ggaagtcact acgcaggtga ggctggaata
      121 agaactatag gatttggtcc ttctaaggaa aatcttgctc atacaataga tgagtatata
      181 gaattagacc aattattcaa aggtgcagaa ggatattatg gtatattaaa atcagtttat
      241 aaaaaataat taggagatgg ttttgtgaga actttaataa aacatgggct tatagtagat
      301 ggaaataaaa caccagcata tgaaggagat attttaatag aaaacgagaa aatattaaaa
      361 atatcacaag atttaaacga agaagctgac aaagttatag atgcaaaagg tagagttata
      421 tgtccaggtt tcatagatac tcatagccat tcagacctag ttattttagt taatccatat
      481 aatgaggtaa agattagaca gggaattaca acagaagtgt tgggccaaga tggtatatct
      541 atggcccctc tacctcaaga gcatatatct tcttggagaa aaaatttagc aggtttagat
      601 ggtgaaagtg atgaaattga ttggaaatat gaaacaacag agaattattt aaaaatgatg
      661 gattacaatg gggtaggttt aaatgaaact tatttagtac ctcatggaaa cgttagaatg
      721 gaagctatgg gacttgaaga tagacctgct actaaagaag aaattcaaaa aatgtgtgaa
      781 atcacagaga gagaattaaa agcaggagct ataggattgt ctactggact tatatatata
      841 ccttgtgcat actcattgac tgaagaaatt atagagatgt gtaatgtagt agcaaaatat
      901 gacggagtat ttgtagttca ccaaagaagt gaagcagata caattttaac ttcaatggaa
      961 gaaatcatag aaattggaaa acaatcagga gtaaaagttc atttttcaca ttttaaggtt
     1021 tgtggtaaag caaactggaa gtatatacca caagttatag agcttttaga aaaagcagaa
     1081 aaggaaggaa taagagtatc ttttgaccaa tatccatatg cagcaggaag tacaatgctt
     1141 ggagtagttt tacctccttg ggcacattct ggaggaactg ataagttaat agaaagatta
     1201 agtgatgaaa acgaaagagc aaaaatgaaa aaagatatag caaatggaat agaaggctgg
     1261 gataatttta tagaatttgc tggaatagac caaatatttg taacaagcgt aaaaacagaa
     1321 aagaataaag atacaattgg taagaactta ttagaaattg gaaaaatgag aggaaaagac
     1381 ccattagatg caacgtttga tttattaaaa gaagaagaaa atgcagttgg gatggtagat
     1441 ttctatggat tagaagaaca tataatagga ttcatgaaaa gagacgagca aaatgtgtgt
     1501 acagatggtc ttttagcagg taaaccacat ccaagagctt atggttcttt ccctaaaata
     1561 ctaggaagat atgttagaga gttgaatgtg ttaacaatcg aagaagctgt ttataaaatg
     1621 actaaaaagg cagctacaag ctttagtata aaagatagag gcgaattaaa agaaggatat
     1681 tttgcagata tagttatatt tgacaaggat acagttagtg gttgtgatga ttttatcaac
     1741 tctatgcagt accctacagg tatagattac gtaattataa atggaaattg tgttgttgaa
     1801 gaaggaaaat acaataaaat taaagcagga aaagtactta aaaattaaat cttagcttta
     1861 aggaggaata aatttatgat tttagtgggg aatgggaggc taataagcca agattcttta
     1921 aatccctata tggaagatgg atgtgtagta ataaatgata atctaattga agatataggt
     1981 actacagaag aaatgaaagc taaatatcca gtacatgaat ttatagatgc aggcaagaaa
     2041 ataatcatgc cgggtctaat aaattcacat atgcatatat acagctcatt tgctagagga
     2101 atggcagttc caggaaaacc ttctgagaac tttttagaga tactaaacaa tttatggtgg
     2161 agacttgaca aacagcttac actggaagat acaaaataca gtgcatatgc aacgtatata
     2221 gaatgtataa aaaatggtgt aacaacagtt tatgaccatc atgcaagtcc aaatgcaatt
     2281 gaaggcagtt tgtttacaat atcagatgtt gcaaaggatt tgggaattag aacgtgtctt
     2341 tgttatgaag tgtctgatag agatggtgga aatacaatcc aacaaggtat caatgaaaac
     2401 gtaaacttta taaaatacgc tcaaaaagat gatacagaca tgataaaagg aatgtttggg
     2461 cttcatgctg catttacact atctgatgat acattaaata aatgtgcttc agagatggct
     2521 ggtcttgata caggttacca tgtacatgtt gctgaaggac tagcagactt acaatataat
     2581 gtagataaat atggaaaaag ggttttagaa agattcaatg attttggagt actaaaagaa
     2641 aaaacaatag cagttcattg tatatatata agtgcagaag aaatcagtct tttaaataaa
     2701 acaaatacat ttgtagttca taatccagaa tctaatatgg gaaatgcagt tggatgttct
     2761 cctgcaatag agttattaaa aaggggagtt acagtaggat taggaactga tggatatact
     2821 agcgatatgt ttgaatcatt aaaagttgcc aatataattc acaaacatca cttaaaagac
     2881 ccaagagttg gatttgaaga atcacaaaca atgttatttg ataacaatag aaaaatagct
     2941 aaagcttatt ataaaaatga cctaggagta cttaaaaaag gtgcttatgc agatgttata
     3001 gtagttgatt atataccaca tactccattg acagaaaata caataggggg acacactatt
     3061 tttggaatga gtggaagaag cgtagataca actattataa atggaaaggt acttatgaaa
     3121 gatagaaagt taataaacat agatgaagaa agtattctag caaaaagtag agaattaagt
     3181 caaaatctat ggaatagaat ttaaataatt gatattaata tacaagtaag aaacaagaat
     3241 ttagatgtta aaaacagagc ttaaacaaaa ataggaattt aaatgaagta tataaataaa
     3301 aaatatacgg aatagaatat taaattaaat atagaaggga gacccaaaat gtctcgagat
     3361 aaaagcccta aaatagctcc agtagatgaa aggttacctg tatccaaatc ttgggtattt
     3421 tcactacagc acgttttagc aatgtgtgca ggagcagtag cagttcctat gatgatagga
     3481 actgctgcac gactagatca tgctagtatt gtttttttaa taaatgcttg cttgtttatg
     3541 gcaggtatag gaacactcat acaaagtgtt ggtataggaa atattgtagg tgctaaaata
     3601 ccagtaatag aaggaactag ttttgccgct gtggcaggta tgacagcaat agcctcatca
     3661 tatagtgatt cacaagttgc aatacagaca gtatttggct ctgtaatagt agctggattg
     3721 ttttgtatat tacttgctcc agtatttgaa aaattaataa gatttttccc tagtgtagtt
     3781 actggaacag ttgttatggt aataggtatt tcactatttc cagttgggat aaaatggata
     3841 actgacaaca aattggaagc ggttgaacca aactcattag cattagcttt agcagtattg
     3901 gcaataactt tactttcatt taaattctta aaaggaattt ggaatagcac agctatattg
     3961 gtaggtatag tacttggtac actactttcc atggcagttg gaatggcaga ttttagtgca
     4021 gtaaatggag ttggttggct taacttaaat gtacctttaa aatttggaat gcctagattt
     4081 gaaccatctg caatactatc attgtgtttg attatgttgg tacttatgac agaatcagtt
     4141 ggtaatatga tagctattca tgaaatggta gacaaagaag taacaggtaa aaatattaaa
     4201 agaggtctat ttggagatgg aatatctaca gcattatctg gaatattcaa ttcatttcca
     4261 ataactccat ttggtcaaaa tacaggaata gtaggtctta caggtataaa atcaagattt
     4321 atagcagttt acgcaggggt tatattgcta gtacttggat tcttaccaaa atttgcagca
     4381 ataataggag caatacctaa gcctgttctt ggaggcgtag gatttgcaat gtttggaatg
     4441 gtaatggttg gaggagtaaa aactttaagc aaagtgaaat ttgatggaac taaaaatggg
     4501 gttatagtag cagttagtgt tggtttgtct atgataccac taacaaatcc tgatttctat
     4561 cataatttcc caacttgggt acaaacaata ttccatagtg gaataacaac aggtagttta
     4621 tcagcagtgc ttttaaacat attcttcaat gaactaggtt ctaaaaaaga aaaaaataat
     4681 aaagttgaag aagcaaaata aaaataaaac aagtaaaaat ctatattgac ttaaagtcat
     4741 taagtattaa taaaaataat tcagagatat taataattca acaaaattat cttatatttt
     4801 aaataatata aaaaagtaaa taaataacga atacaaataa aagaatacaa tttaaatatt
     4861 aaaaatattt aatttaaggg agagataata atatggctaa tttaaaagtt aatttatatg
     4921 gaatggaatt tttaaaccca attatgacag cggcaggacc tggagcaaaa gatggtgctc
     4981 tctgtcaaga ggcagcaaaa ggtggagcag gagctatatg tacaaaaact atatctgtat
     5041 taccagctga tgtaccaaga ccatgtatgg caaaaactaa tagtggtttt ttaaacacag
     5101 aattatggtc agagcttcca aaagagcaat ggatagagga agaatacaaa aaggtaaaag
     5161 aaacagggct tccagtaata gtaagtatgg gatattcagc agagcaaata gctgaggttg
     5221 ctcctttagt aaagccttat gcagatgcag ttgaattatc tactcattat gtaggtacag
     5281 acgttgcacc aatagtaaat gctttaaaag ctgcaaaagc tgttttagat gtaccagtat
     5341 ttatgaaaat gagtcctcat actgacattc aaactattgc aaaagctgtt gaagaagcag
     5401 gtgcagatgg acttgtaatg ataaactcat ttggaccatg tatggcaata gatgtaaata
     5461 caggataccc tataatggga agtaaagctg gatacggatg gttatcaggt gcaccaataa
     5521 gacctctagc aataagatgt atatatgaag cttctcaagt tgtaaatata ccaataatcg
     5581 gtgttggtgg aatcacttgt ggaaaagacg tggctgaaat gatgatggct ggagcaagtg
     5641 ctgttcaagt atgtacagaa gcaatcctta aagggccttc tatctatgga aaaattgcta
     5701 aagaattaaa tgaattttta gatgagaatg gatatgctga tgttaatgaa ataaaaggat
     5761 taactcataa gaaaatggca gctagagggt ttagaactca ttcagtagct ccagtagtgg
     5821 atgataacaa gtgtatcaaa tgtaagcaat gtgtaacaag ctgtgtatac gaagctttag
     5881 aagttacaga taagttgaac atagatgcag acaagtgttt tggatgtgga ttatgtgtaa
     5941 ctagatgtcc aaaaggagct ttaagcatct gctacaatca agtagaagct atgaatgagt
     6001 aataattata tagaattttg gtaattaact tagagtaata ggtattagga taataaaata
     6061 tatcagataa acaaacacac attatgcatt aataatacag tctaaagtta ataattttat
     6121 tatattgatt taactaaata ttagtttagc tgaatattaa tttaattagg tattggttta
     6181 atcttaatat agatttactg cgtataagtg aactaactag attactttaa gttaattttt
     6241 tcatataaaa taaattgata cattacaagt aaggtggagt ctatatggga attgttttaa
     6301 aaggtgggaa agtagtaaca agtgaaaaaa cttactgtgc agatgtaaga atagaagatg
     6361 aaaaaatagt cgatataggt cttgatatat caaaagaaaa tgatgaaata gttgatgtta
     6421 gtgattctta tgttatacca ggaggtatag atacacacac acactttgac ttagatacag
     6481 gcgttactaa gacagcagat aactttgaga caggaacaaa agctgctata gtaggaggaa
     6541 ctactactat attggatttt gctacacaag ctaaaggatg ttctttgaaa gacggattag
     6601 aagaatggca tgaaaaagct aaggataaat cctattcaga ttatggcttt catatggcta
     6661 taacagattg gaatgactcg gtttgtaatg aaatggagga tatggtgaaa gagggagtat
     6721 cttcatttaa actgtatatg gcgtataaag gaagccttca agttgatgat ggtgtaatct
     6781 ttgaagcatt gagaaaagca gaagagatag gagggattat tggtttccat tgtgaaaatg
     6841 gggacataat atgtgaactt gtggataaag caaagtcaga aaataattta tctccaaaat
     6901 atcatcaatt aactagacca gctataatgg aggcagaagc tacatcaaga cttatgaaga
     6961 tagctgaagt tgcaaactct aaagtatatg tagttcactt aagctgtaaa gaatccttag
     7021 aggaggtttt aaaagctaag caaagaggtg tggatgtaat agttgaaact tgtcctcaat
     7081 accttctatt aaatgatgaa ttatatgatt tagatggatt tgaaagtgct aagtatgtaa
     7141 tgtcaccacc tttaagaaat aaagaaaata atgaaatatt atggaatgct attttagata
     7201 atcaaataga cactatagga acagaccatt gttcttttaa ttataaggga cagaaggaac
     7261 ttgggataaa cgatttcagt aagataccaa atggttctcc aggtgtagaa cataggatga
     7321 gtcttttata cacatatgga gtctgtaaaa ataaaatatc tatcaacaag atggtagaag
     7381 taacatcaac taatgcagca aagttgtttg gaatgtatcc taataaagga actatagaaa
     7441 taggcagtga tgcagatata ttagtcttaa atccaaacaa aaaatccaaa atagaagcaa
     7501 aaaaacaatt acaaaatgta gattatacac cttatgaagg gtatgaagtg gattgtcaaa
     7561 tagaacatgt ttatttaaga ggaaaagaag tagttagaga tggagaatta atttgtaata
     7621 ctccaagtgg gagatatata aataggcgtc taacaaaggg ggctagagaa tggtagaatt
     7681 tatattaaat ggagagaaag ttgttgcaaa agaaggcaaa aaacttttag acttccttag
     7741 agaagatatg aatataactt cagttaaaaa tggatgttca gaaggtgctt gtggaacatg
     7801 tatggttata atagatggta aagctactaa agcatgtgta tttaaaactg ataaattagc
     7861 tgggaaaaac ataacaacta tagagggatt atcagagaga gaaagagatg tttttgcata
     7921 ttcttttgct agtcaaggag ctgtacaatg tggattttgt attccaggta tggtaattag
     7981 ttcaaaagca cttatagacg ttaataataa tcctactgaa gatgatataa agaaagcttt
     8041 aaaaggtaat atatgtagat gtacagggta tgtaaaaata attaaagctg tcgatttagc
     8101 ggcaaagatt tttagagaaa atatagatgt gccaaaagta aactgtaagg gtctagtagg
     8161 tgaaaatctt cctagagttg atgcagttgg caaagcactt ggatattctg aatatgtaga
     8221 tgatatgaga attgagggta tgatttatgg ttcagcagtt agagctaagt atcctagagc
     8281 tttagttaaa aaaatagata tagaagaagc aaaagcttat ccaggagttg ttgcagttct
     8341 aacagctaaa gatattccag gaactataaa ggtagggcac ttaaagaagg attgggatac
     8401 tttaatacca gaaggtgaaa taactagata cttaggagat ggaatagttt tagtagcagc
     8461 agaaactaga gaagcgttag aagaggccaa aaagctagtt aagatagatt atgaggaatt
     8521 aacaccatta agtactacag cagatgcact tagagaagat gctccaaaga tacatgagac
     8581 agggaatata cttgttaagg aacatttagt aagaggaaac gctaaagaaa agatagaaaa
     8641 ttcaaaatat gttgtaacta aaagatatac tacacctgct acagaacacg catttttaga
     8701 gcctgaatgt gcagtagctg gtccttatga agatgatgga gtaataatct attcaacaga
     8761 ccaaggggtg tttgccactc aacatgaatg tgcagatatg ttagggttac catatgagaa
     8821 ggtaagagtt ataaacaaaa tggtaggagg agggtttggt ggaaaagaag acatgagtgt
     8881 tcaacaccat gcagccttac ttgcatacca tacaaagaga tttgtaaaag tacagttaac
     8941 aagaaaagaa agtattattg ttcatccaaa acgacatgcc acagaaatgg aatttacgac
     9001 agcatgtgat gaaaatggat acttaacggg tatgaaggca acgataatat ctgacacagg
     9061 tgcatatgcc tctcttggag gaccagtgct acaaagactg tgtactcatg cagcaggacc
     9121 atacaattat caagatattg atataacagg aacagcagta tatactaata accctcctgg
     9181 aggagcattt agaggatttg gagttacaca gagttgtttt gcaactgaat gtaatctaaa
     9241 tttacttgct gaaatggttg gaatatctcc ttgggagata agatataaaa atgcaataag
     9301 acctgggcaa gttttaccaa atggtcaatt tgcagatgaa ggaacagcaa tggcagagac
     9361 actagaagct gtaaaagaag agtatgaaaa gcatccacgt gcaggtatag cttgtgctat
     9421 gaaaaatagt ggggttggag ttggtatacc tgatgttgga agatgtagat tggtgataaa
     9481 agatggcaaa gttcacataa gaacaagtgc ttcttgtata ggtcaagggc ttggtactgt
     9541 tatgactcaa gtagtttgtg aaactgctaa cctacttcct gaaaatatag ttcatgaagt
     9601 tccagatact catttaacac cagactctgg taatactacg gcttcaagac agacagtatt
     9661 tacgggagaa gctactaagg ttgcatcaaa taagttaaaa gaagctttag actctggcaa
     9721 aactttactt gatttagagg gagaagagtt ttatggagaa tatgaaagta ttacagataa
     9781 aatgggttgt gacaaagaaa atccagtaag tcatgttgct tatggatatg caacacaagt
     9841 tgtaattctg gatgaaaatg gaaaactaga aaaagtagta gcagcacatg atgttggaag
     9901 agctataaat ccaatcagtt tagaaggtca aatagaaggt ggagtagtta tgggtcttgg
     9961 atatgctcta accgaagatt acccagtagt taactctatt cctacagcta agtttggtac
    10021 attaggttta tttaaatcta cagatatacc agaaatacaa gctttaatag ttgaaaagaa
    10081 caaagattta ttggcttatg gggcaaaagg tgtaggagaa atttgtacag ttcctactgc
    10141 accagcagta caaaatgcct attatgtatt tgataaagaa tttagaactg agttaccact
    10201 acaaaatact ccatatagta aaaaaaagta acaaaaaaaa gaaatattaa ataaaaaaat
    10261 agatgaaatt gtaaataaaa aaaacccttt tgcataaggt atattttaaa tgatagaata
    10321 tacatataca ggagggtttt tcttttataa aataagttta ataaaattga gaggtgagca
    10381 gaatgaattt taataatagt ctagaattaa ctcagtctca gaagctaata atgactacac
    10441 aacttaagca atcattatca atattaaata tgagtaagtt agagttagaa gaagagataa
    10501 aaagagaagc agagaataac ccattagttg aagtcgagaa aagtggggag ataaattggg
    10561 aagagtatat aaaagacatg gataggtcaa gacgtttaga tagaacagag ataagctata
    10621 atcctgataa tgaagttaat ctagaaaatt tagttaaata ttcgtcaaat ttatatgaag
    10681 atttaaaatt tcagataagc ctgtataaac ttacagacaa agaattggaa gtctgtgagt
    10741 atataattga tagtttagat gaggatggat atttaagaac tgaggaaaaa gtaattgttg
    10801 ataccttaaa gatagatgaa gaactttttg aaaaatgttt aattagtgtt cagcagttgg
    10861 aacctagtgg agtaggggca agaagtcttt cagaatgtct gatgatacaa atggctagtt
    10921 taggaatata taatgaaatt ttagaggaaa tcgttacaaa agacttaaat ttaattgcaa
    10981 ataataaata caaagagata agtaaaaagt acaatatgtc attacaaaaa tgtgttgaac
    11041 taataaacat aattaagaca ttagacccca aaccaggaag aacttgttca gtagagaaaa
    11101 gtgtatacat tcaacctgat gtaacagtag aaaaaattga tgatgaattt attgtatatt
    11161 taaatgagaa agattcttat caaataagaa tcaatagtta ttataaagac atattaaaaa
    11221 attcacagtc tgatgaaagt gcaaaagaat ttataaaaga aagactaaat tcagcaacag
    11281 gacttatgaa aaatatagag agtaggaaaa ctacagtact taagattgca gaagagatag
    11341 taaaagctca agatgaattt ttgagaaaag ggacaaaata tataaaacct ttgaaaatga
    11401 aagacatagc agaaaaatta gaatttcatg aatctactat aagtagaggt gtaaatggta
    11461 aatatatgct aacacctttt ggcgtatatg aatttaggta ctttttcagt agcgccattg
    11521 agactgagaa taatgaaatg gcatctagta caagcataaa aaaaattata aaggaaacaa
    11581 taaaagacga aaataaaaag aaacctttaa gtgatgacca tatatctaag ttattaaaag
    11641 aaaaaggaat caatgttgca agaaggacag ttgccaaata tcgtgaagaa ttaggaatcc
    11701 catcttcaag taagagaaaa gaatactaat aagtaaaaga caaatatcag tatggtaagg
    11761 ggaaaaggct aattaagaga tgaatgtaga ttgggctaaa aattttataa agtaaaataa
    11821 tataatatga aaaagtatta aaatgctata aggtattaaa aaactgggga acattaaaac
    11881 attaagatag caaagaacat aaaaaactaa agaagattaa aacattaaag aacattagag
    11941 ctttgaggaa tattagaact ttaaagaata ttaaaattta taaaatataa aaatactaaa
    12001 aagaattgaa aaactgggga acattaaaat attgtaaaat gctaaaaaac tagaaaacat
    12061 aattaaataa gtgcttataa agaatgatta aattaaataa gtgtttgtaa agaataatta
    12121 gatattagaa aaagaagaat acctagataa ataaactatt attaaattta ataatcacaa
    12181 aaggaaaaca cgtagggtat aaataaaaat cttaactaga taaaagtaaa cttagttgta
    12241 gataaaaata actagaaata aaattattta tagtaataaa tattagaatg aaaatataaa
    12301 aaaatatata taaaaagcct tatataaaaa gaaaaaatac tgtgatttga aaatggtgga
    12361 gaaatatttt ataaaataaa aaaataaaaa agtttttgaa aaactattga aatctatacg
    12421 caaatcctat aaaataaaaa tatcttgtgg gacttaaata aacactaggg acaaaaaaag
    12481 tcccgaaagg aaagcaataa ggagtatgtt atgaagaact tattagaaat tcaaaagaaa
    12541 ttgattccac aggcaattga acttatggaa agaagatact ctattttaag acaaatatct
    12601 ttaagtgaac caataggtag gagaacatta tcaaatgtat tagagattag tgaaagaata
    12661 atcaggtcag aaactgagtt tttaaaagaa caaggactta tagacgtagc tgtatctggg
    12721 atgactatca ctaaagaagg ttctgatttg ttagataaac ttaaggacat catgagtgac
    12781 atcatgggat tgtctaagtt acaagataga gtcagagaaa agcttggaat aaaaagggta
    12841 atattagttc ctggaagctg tgatgaaaat ggaagtttac taaaagatgt aactagatat
    12901 ggatgcgaat atttcttagg cattttaaaa gatggagata tcgtttcaat aacaggagga
    12961 agcactatgt tggagttttc aaacgttatt aaaactgata agagatatcc aaactctaca
    13021 atagttccag ctagaggaag tatgggaact gatgtagaga tgcaatctaa caatatagtt
    13081 gcttcaataa gtaagaaatt acattctaat tgcaaacttt tacatatacc agatgagttg
    13141 gatgaaagtg caatgaaaac tcttagccaa gtgccagaga ttaagacaac tttggagtat
    13201 attaaaagaa cagacatttt agtttttagt ataggtagag cagatgtcat ggcaaagaga
    13261 agaaaacttc cagaagacaa ggttgatgag atattatcta aaaatgcagt tggagaagca
    13321 tttggatatt atttcaacaa agatggagaa atagtttaca aactgaacac tgttggaatt
    13381 gatttagaaa cagttaaaca agtaaaagaa actattgcaa tctttgcagg gactgaaaaa
    13441 gtagaagcct tattagctat atcaaatatg cataaaaaca tggttcttgt aacagatgaa
    13501 gaaagtgctt ataagatatt gtcattatta taaaagtcaa gacctagcac agagctagaa
    13561 aacatacatt tactttatag gaggtagcga aaatggttaa agtagctata aatggatttg
    13621 gaagaatagg aagattagca ttaagaaaaa tgatggagca acaagataag ttcgaagttg
    13681 ttgcaataaa cgacttaaca gacgctaaaa tgttagctca tttatttaaa tatgatacag
    13741 ctcaaggaag atttaacgga gaaatagaag ttaaagaagg tgcttttgta gtaaacggaa
    13801 aagaaataaa agtaacagca gaaagaaatc ctgctgacct accatgggct gaattaggag
    13861 tagatatagt attagaatgt acaggattct ttacatctaa agataaagct gaagctcata
    13921 tacaagcagg ggctaagaaa gttgttatat ctgcaccagc tactggagat ttaaaaacaa
    13981 tagtattcaa cacaaacagt gacatattag atggttctga aacagttata tcaggagctt
    14041 cttgtactac taactgttta gctccaatgg ctaaagtatt aaatgataaa tacggtatag
    14101 aaaaaggatt aatgactact atacatgcat acactaatga ccaaaatact ttagatggtc
    14161 ctcatccaaa aggtgattta agaagagcta gagctgctgc tggaaacata gttccaaaca
    14221 ctacaggagc tgcaaaagca ataggcttag taataccttc attaaaagga aaattagatg
    14281 gggcagcaca aagagtacca gttgtaactg gttcaataac tgaattagtt tgtacattag
    14341 gaaaaaatgt tacagttgaa gaaataaatg cagctatgaa agaagcttca aacgaatctt
    14401 tcggatatac tgaagaaatg ttagtatctt ctgacataat cggaataagc tacggttcat
    14461 tatttgacgc tactcaaaca aaagttatgg aagtagatgg aaaacaatta gttaaagttg
    14521 tttcttggta tgataatgaa atgtcttata cttctcaatt aataagaact ttaggatact
    14581 ttgcacaatt agcaaaatag tcagttttga gaaaatagaa aagtagattg acaaagtccg
    14641 agtttgtagt ttaatactac ggactcagga ctttttttaa gaaaaaatat ataaaataca
    14701 cctaaataat gttacatact atatataaaa atatgataat atgatatatt taatagggta
    14761 aaagtatgta ctatattata cttggcaata aaaaattact ttattaaaag gagagatatt
    14821 tatgtcaatg cttaacaaaa aaactataga agatattgat gtgtgcggaa aaaaagtatt
    14881 agtaagatgt gactttaatg tgccattaca agatggtgta attactgatg aaaatagatt
    14941 gaacggagct ttaccaacta ttcaatattt aatttctaaa ggggcaaaag ttatattatg
    15001 ctctcactta ggaaagccaa aaggagaagc taaaccagaa ttatctttag caccagtagc
    15061 aaagagatta tctgagatgt taggaaaaga agttgtattt gcagcagacg ataatgttgt
    15121 aggagaaaat gcaaagaaag caactgaaaa aatggaaaac ggagatgtag tattattaga
    15181 aaatactaga tatagaaaag aagaaactaa aaacgaagag aatttctcta aagaactagc
    15241 atcacttgct gaaatatttg taaatgatgc atttggaact gctcatagag cacattgctc
    15301 aacagttggt gcaggcgagt ttttacaaga gagagtttgt ggatacttaa ttcaaaaaga
    15361 attaaaattc ttaggagaag ctgttgcaaa ccctgtaaga ccatttacag ctatacttgg
    15421 aggagctaaa gtttctgata aattagctgt tataaacgaa ttattagaaa aagttgataa
    15481 tctaataata ggtggaggaa tggcttatac attcttaaaa gctcagggtt atgaagtagg
    15541 aacttcttta cttgaaatag ataaagttga atatgctaaa gaaatgatgg aaaaagctaa
    15601 gaataagggt gttaacttat tattaccagt agacgttgtt atggcagacc actttgcacc
    15661 agatgctact ccaatagtaa cagaagatgc taatgtaaaa gaagattaca tgggactaga
    15721 tatgggacct aagactatag caaactttgt aaaaactata aaagaatcaa aaactgtagt
    15781 atggaatggg ccaatgggag tatttgaatt tgaaaacttt gcaaatggta cattatcagt
    15841 agctagagct atggcagagt tgactgatgc aactactgta attggcggtg gagatagtgc
    15901 agcagcagtt aatcaattag gatttggtga caagatgact cacgtatcaa caggtggagg
    15961 agcatcacta gaatttttag aaggtaaaga attaccaggt attgcagcat tagataataa
    16021 ataaactaat atatagagga gattgtaaaa tgagaaaacc tataattgca ggaaactgga
    16081 aaatgcataa aacaataaaa gaagctttag aatttgtaaa tgaagttaaa gataaagtaa
    16141 attctgataa agtagaagct gttatatgtg caccatttac tttattaaag gatttaaaag
    16201 aagctactaa gggtacagat ataaagatag gtgctcaaaa tatgcacttt gaagaaaaag
    16261 gagcatttac aggagaagtt tcacctctta tgttaaaaga aatagatatg gactatgtcg
    16321 taataggaca ttcagaaaga agacaatact tcaatgaaac tgatgaaact gtaaacaaga
    16381 aagttttaaa agcattagaa gtaggaatag acccaatatt atgtgttgga gaaactttag
    16441 aacaaagaga agctggaaaa actaaagatg tttgtaaagt tcaagttgaa aaagctttag
    16501 aaaatgttct taaagatgat ttagcaaaag tagttgttgc atatgagcca atctgggcta
    16561 ttggaactgg taaaactgca actgctgaag atgctaatga cgttatatct tatataagag
    16621 aagttataaa aggattatat ggagaattag ctaatgaagt tagaatacaa tacggtggaa
    16681 gtgttaaacc ttcaaatgta gccgaaataa tgggtcaaag tgatatagat ggagctttag
    16741 taggtggagc tagtttagct agtaatgatt acctagacct tgttaatttc taaggagtga
    16801 aatgatgaaa aaaccagttg ctttaattat tatggacggg tttggataca ataaggatgt
    16861 taagggaaat gcaattgctg agtccaaaac tcctaattta gatagaataa aaaaagagta
    16921 tccaaacaca ttgataaatg ctagtggtct tgatgttggt ctacctgatg gtcaaatggg
    16981 aaattcagaa gttggacaca ctaacatagg tgcaggtaga atagtatatc aagatttaac
    17041 tagaataaca aaatctataa aagatggtga cttttttact aataaagttt tatgtgaagc
    17101 aatggataat gcaaaagaaa attctcttca tgtaatggga cttttgtctg atggaggagt
    17161 acattcacat atagaccatc ttaaggctat aatcaaaatg gcaaaagata aaggcgtaca
    17221 aaaggtgtat gttcacgcat ttactgatgg tagagatact gaccctcaaa gtgcattaga
    17281 atatgccaaa gaagtacaag ctagtatgga tgaaattgga gtaggtgaat ttgctacagt
    17341 ttctggtaga tactacgcta tggatagaga taagagatgg gaaagagtag aacttgcata
    17401 caatgccatg gttagaggta ttggtgaaaa agcaaattct attgaggaag ctattcaaaa
    17461 ctcttatgat gatggaaaaa atgatgagtt tataatgcca acagttatta tgaaagatga
    17521 taaaccagtt ggaagtataa aggaaaatga ttcaattata ttcttcaact ttagaccaga
    17581 tagagctaga caaataacta gagctttagt ttgtgaagag tttgatggat ttaaaagaga
    17641 agatattaaa aacttctttg tatgcttaac agagtacgat ataactatag agaatgtgca
    17701 tatagcattt ggacctcaat ctttagccaa cactctaggt gagtatctag ctaaaaatgg
    17761 aaaaactcaa cttagagctg ctgaaactga aaagtatgca catgtaactt tcttcttcaa
    17821 tggtggagta gaagagccaa ataaaggtga agaaagacta ttgatacctt ctccaaaggt
    17881 tgcaacttat gatttaaaac cagaaatgtc agcatatgaa ttgacagata aagctttaga
    17941 taaattagga gaagataagt ttgactttat agtattaaac tttgcaaatc ctgatatggt
    18001 aggtcataca ggaagtatag aagcggctat aaaggctgtt gaaactgtag atacttgtgt
    18061 aggaagattg atagataaaa tagtagagtt aggtggaagt gcaataataa ctgctgacca
    18121 cggaaatgct gaatatatgt tagacccaga aacaggaaaa actgtaacgg ctcactctat
    18181 taatccagta ccatttattg tagttggtca agaatatgaa agtgcaaaat tattggatgg
    18241 aggaagatta tctgatatag caccgactgt tttagatatg atgaagttag aaaagccaga
    18301 agaaatgact ggtcattcac ttatttcaaa atagtcgatt ctgataagta gagaataata
    18361 tataaactac aatataaatt taaaaataat gcagtttagg tttattttgt aaagtttaga
    18421 ctttatgaca taagatttaa attttgtaag ttctggatat tgtaaggtgt agatgaagat
    18481 atattttata aaatttacaa gatagacaat ttataaaata aaaaattaca atatagataa
    18541 taatgtaaat aatgatataa ataataacaa gatagacaat aacaatataa ataataataa
    18601 ttaatatata ttatataagc aaaaatttta gaatcattag ttgtacattt tatgtttaat
    18661 gttttaaatc tagttataat atttgtgtat ttaagattgg ttttggattt tagacaagtt
    18721 tttttatatt atataaatta aaatattata aaaaataaaa taaaaatagg aacttttaca
    18781 aatttaccca tcaaataaat ttgtacctaa ttttcaaaag caactttatg tactataata
    18841 tagaaagtag attaaaatag tagacggatg tttacagtaa atgaaaattt aactaataga
    18901 aaatcgaagg gagatataca aatgtcagtt attgaattag tatatgctag agaagtatta
    18961 gactcaagag gaaatccaac tgtagaagtt gaagtagtat tagaagatgg agcaatggga
    19021 agagcaatag ttccatcagg agcatctaca ggagcttttg aagctgttga attaagagat
    19081 ggagataaag gaagatactt aggaaaaggt gtagaaacag ctgttgctaa cgtaaatgaa
    19141 ataatagcac ctgaaataga aggaatggat gcatttgacc aaccagctat agatgcaatc
    19201 atgatagaat tagatggaac tccaaacaaa ggtaaattag gagctaatgc tatattaggt
    19261 gtttcaatgg cagtagctag agcagctgct gatgaaatag gtttaccatt attccaatac
    19321 ttaggtggag taaatgctaa acaattacct gttccaatga tgaacatatt aaatggtgga
    19381 gagcatgctg ataataacgt tgatgttcaa gaatttatga tattaccagt aggagcttgt
    19441 tgtttcaaag aaggtttaag aatgggagca gaagtattcc attcattaaa gaaagtttta
    19501 ggagaaaaag gattagcttg tggtgtaggc gacgaaggtg gatttgctcc aaacttaggt
    19561 tcaaacagag aagctttaga attaatagtt gaagctataa caaaagctgg atataagcca
    19621 ggtgaagacg ttatgttagg tcttgacgtt gctgctacag aaatgtacaa caaagaaact
    19681 aaaaaatacg ttttagcagg agaaggaaaa gagttaactg ctgctgaaat ggttgcttta
    19741 tatgaagatt ggtcaaacaa cttcccaata ataactatag aagatggttt agacgaagaa
    19801 gattgggatg gatggaaatt attaactgaa aaattaggta ataaattaca attagttggt
    19861 gacgacttat ttgttactaa cacagagaga ttagaaaaag gaattgaaaa tggagtagct
    19921 aactctatat tagttaaagt taatcaaata ggtacaataa ctgaaacttt agatgctata
    19981 gaaatggcta agagagcagg atatactgct gttatatctc acagatcagg agaaactgaa
    20041 gattctacta tagcagattt agctgttgca gtaaatgctg gtcaaataaa aactggtgct
    20101 ccatcaagaa ctgatagagt tgctaagtac aaccaattat taagaataga agaaatggtt
    20161 ggagagcaag ctagatattg tggattaaaa tctttctata acttaaaaaa atagttatta
    20221 aaatggttac taaaaaagat taatgaagag agaatataag atatttaagc tcatcttata
    20281 agatataaaa gagataagtg ttaattgatt tttcaaggca cttatccttt tttatatttt
    20341 attacttaat tttattcata gattcagaaa aaatatgaat aaatgtttct atctcatttt
    20401 tatctaattg cataggaggt ttttattaaa aaataaaagt gaagacatat tttgatttaa
    20461 tcataattgt cattaaagta ttattgctaa atgtggatta tttattttaa attatgttga
    20521 aattaaaagt tatatcaata ttttaaaatg attgttttat tttggtggct atttataata
    20581 tatgcaatga gagtagatta ttttaagtgt taatttatgc attaatttat gtattaattt
    20641 aaatagtttt ctcttctaag ttttattcat ttttatattg agaatatagt aatatattat
    20701 agtaacaata tatttttttg tatgttattt atagcataat agtcttgaaa tggctatatt
    20761 attgtgatac actaaagagt aatgaaattt aagtaataaa cagataggag gggcaagaat
    20821 gagcaacatt ttaatgggtg tgcaagtagt actagggatt ttactagtaa ttagcataat
    20881 gcctcaagat tctaagaatg ctttaccttc agaatttggt ggagaaggaa gccaagctta
    20941 ctttaaacca aaaggaaaac aagcatttct tgctagagtt acaaagataa cagcagtatt
    21001 attttttata aatgcattgg cattacttat agttaagaag tagtgatatt gttgaataac
    21061 tggccattat ttaattagtg catttgctag acatttaaaa attaaattta gtttttaata
    21121 aaagtacatc aacataaaaa gtacgtaaaa taaaagctgg actaatgatt ttatatgatt
    21181 agtccagttt ttattttata gattgactat ttgttggcgt ttattatttg tatttatata
    21241 ttgtttgtat ttatatattt ttttcaaact aaaaaatata tagcaacact actttcacca
    21301 tgtttaatga gataatatac acaaagttat attatatagt aaaaatagta taataatatg
    21361 tttttacgca attaaatcga ttttatatat gtttctcata ataccaattt gtgttatcaa
    21421 atatcattaa ataagattat tctgctttaa aataaatatt attaaaaata ctgtaagtat
    21481 agaaaatcca gaagtaaata ctacaatttg tccagctaat tcactgtcag aatccatctg
    21541 ttgtgccatt gtaaatgaag aaactgcagt tggagcagat aacattatca taagtgaagc
    21601 taattctaca tttctaaatc caagaaaaat gctaattggt aaaaatatag caggtacaag
    21661 tataagtttt ccacatacgc ccaatataat gggttttata tgccccttta tagcagaaaa
    21721 actaaaagag ccgcctagaa ttataagtga taaaggagta gctattttag aaatatcacc
    21781 aatagttttg tgtaaaaatg taggtatatt aatatttaaa attagcattg tcaatcctat
    21841 aaaagaggcg attatgagtg gatttgttaa gacgctttta atcatatgtt ttatatttac
    21901 tttgccacct ctaaaaattt caagaattac aacagataat acattaaaca taggtacaat
    21961 aactgcaatt aataaagatg tgactccaat actcttatcg ccaaataatg aaattgtcac
    22021 aggaatacca aatataacga aattgctacg aaatacacct tgtattaatg caccccttgt
    22081 cttattatct ttttcaattt taggaataat aaagactaag attaagaaga ttgaaaaaat
    22141 aattataaca gctacagcca taagcctaaa attaagagaa ccatctaaat ctgtattgta
    22201 tatattaaaa aataataata atggcaagaa agacttgaag cagacattat tcattttatt
    22261 taaagtatga gtatcaaata gacctaattt ttttagaaca tatccaagtg acattgtgag
    22321 aaacaaagga agaacaacat ttattgatag gattaaattt tccaaggttt actctccgtg
    22381 attctatgat ttgataattc aattaaattt ccattagttt ttttcaaata aatagatttc
    22441 atattaccaa agacacctgt acattctaca attcctcgct taatttgaat ctcattttgt
    22501 tctaagtatt tttttggctc atcaatattt gtgtttattt taaaacataa gttatctcta
    22561 cttgcttttg aatttttaac ataaggtaaa aatttataac cttttatgtt aagatttatc
    22621 ttaacatttc tagcattaag tttataattt ttgctcattt ctttagatga aaaaccaaat
    22681 tttttataaa aattgatata attttctata ttattattag taatgaccac atgttctatt
    22741 ttttttatca tggcaactcc ttaaga
//
LOCUS       DAEPUT010000065        22367 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.067, whole genome shotgun sequence.
ACCESSION   DAEPUT010000065 DAEPUT010000000
VERSION     DAEPUT010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22367
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.067"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(138..1328)
                     /locus_tag="KRL22_002680"
     CDS             complement(138..1328)
                     /locus_tag="KRL22_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1273152.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(1588..2019)
                     /gene="dut"
                     /locus_tag="KRL22_002681"
     CDS             complement(1588..2019)
                     /gene="dut"
                     /locus_tag="KRL22_002681"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBH1273153.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            2132..4360
                     /locus_tag="KRL22_002682"
     CDS             2132..4360
                     /locus_tag="KRL22_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBH1273154.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNDDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(4471..4956)
                     /locus_tag="KRL22_002683"
     CDS             complement(4471..4956)
                     /locus_tag="KRL22_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1273155.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            5208..6431
                     /locus_tag="KRL22_002684"
     CDS             5208..6431
                     /locus_tag="KRL22_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH1273156.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            6435..9569
                     /locus_tag="KRL22_002685"
     CDS             6435..9569
                     /locus_tag="KRL22_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HBH1273157.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSSGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            9603..10901
                     /locus_tag="KRL22_002686"
     CDS             9603..10901
                     /locus_tag="KRL22_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBH1273158.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYDRYKKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(11190..11435)
                     /locus_tag="KRL22_002687"
     CDS             complement(11190..11435)
                     /locus_tag="KRL22_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1273159.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(11649..14276)
                     /locus_tag="KRL22_002688"
     CDS             complement(11649..14276)
                     /locus_tag="KRL22_002688"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH1273160.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLAALEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(14337..15179)
                     /locus_tag="KRL22_002689"
     CDS             complement(14337..15179)
                     /locus_tag="KRL22_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBH1273161.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(15186..15824)
                     /locus_tag="KRL22_002690"
     CDS             complement(15186..15824)
                     /locus_tag="KRL22_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273162.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(16260..17552)
                     /locus_tag="KRL22_002691"
     CDS             complement(16260..17552)
                     /locus_tag="KRL22_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH1273163.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(17589..17945)
                     /locus_tag="KRL22_002692"
     CDS             complement(17589..17945)
                     /locus_tag="KRL22_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBH1273164.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(17980..18339)
                     /locus_tag="KRL22_002693"
     CDS             complement(17980..18339)
                     /locus_tag="KRL22_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273165.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(18408..20381)
                     /locus_tag="KRL22_002694"
     CDS             complement(18408..20381)
                     /locus_tag="KRL22_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH1273166.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(20603..21616)
                     /locus_tag="KRL22_002695"
     CDS             complement(20603..21616)
                     /locus_tag="KRL22_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBH1273167.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(21629..22174)
                     /locus_tag="KRL22_002696"
     CDS             complement(21629..22174)
                     /locus_tag="KRL22_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBH1273168.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
BASE COUNT         7671 a         3731 c         2887 g         8078 t
ORIGIN      
        1 agagaaaata aataaaaagc aggtatcaat caaatagtaa catgtattat actatacatt
       61 actatcaata ttgtacctgc tttcatatta taagcaataa agaaaaatct atttattagg
      121 ttttataata aaaacaatta taaaactctt cttgcattta catatctact tgaatagtag
      181 ctactattta tattagatat tgttactttt tttgatgaac ctgaagatgc atgtatcata
      241 tctccatttc ctatgtatat tccaacatga cttacagaac cattatttga accttgtgta
      301 tcaaagaata ctaaatctcc acttctaagg tctcctctat ttacatatgt tccatactta
      361 ctttggtctc tagatactct tggtatacta actcctacag attttttcat aacgtactgt
      421 gtgaatccag aacagtcaaa actatttgga ccttctgctc cccatacata tggttttcca
      481 agtagtgtct ttgcaaaact tattacacta tcagctcctt gacttggaga attagtcgaa
      541 taagatggaa ttgaagtatc aacagaacct ttttcagcaa ggtattgact tgacacatat
      601 ccagtttgat tgccataact tacttttgtc catcctccac tttcagaaat acttccaacc
      661 tcagtaccat aacttaatgt agctatttta gaatgacttg tacctggtcc tgttctaacg
      721 ttcaatgact ttgctgttac aacctttgta ccctttacaa ggtcatttga actgttttca
      781 gcattttcat ttgtagagtc atttacacta gttcctaaat atttacttga aacataacct
      841 actctaccat tagaacttat ttttgaccat ccatttgact cagatatgta tccgacttca
      901 gtcccatatc ctagtgttga tattttagaa ctacttgtac ttggtcctgt tctaaaattt
      961 aatccttttg ctgttacaac ttttgtcgac ttaactgaag tatcactact ttcattgcta
     1021 cttccaaggc tatttattgc tacataattt ccatgcacat aacctgtgtt tccattatat
     1081 ttaactttta cccaagaacc ttcttttcct acgtactcaa ctttatcacc tttgtaaagt
     1141 ttccccattg attcatggtt tgtacctggt ccttttctaa aatttaccgc attccctgtt
     1201 attgttctgc tttctatact cacactctct acttcagact cattagcata tgctaaattc
     1261 cccatagtag gcattattat cgcagttgcc attatactgg ctgctattct cttttgatta
     1321 aaattcataa ctttccactc atctcctctt ttctactatc tttatttcac ttcaaaatat
     1381 aaaagaaata attgacacta ttaaaatatc aattatttct tttatattaa tattattaca
     1441 aatttgtaac tatttgtcta tagtaatatt tgcttaccat aaattaccat gtataaattt
     1501 taatctttaa tagcctgtaa tttagtaata tagccatctt ttaccttttt taaaaatggc
     1561 tatatttttt aacttttttg taacttttta aaatccagtt gagccaaacc caccttttcc
     1621 tctttcggag tcacttaatt cttttacctc ttctatgtta atatcataga taggttttac
     1681 tatcatttga gcaattttca tatgcttttc aaccttaaaa tcatttttac catgatttat
     1741 taatataatt ttaagctctc ctctgtatcc ttcgtcaata gttcctggtg tatttaatac
     1801 agtaacagaa tgctttaagg caagcccact tctaggtctt acctgcgctt ctgtcatagt
     1861 aggaagctct atacatatcc cagttttgat aagtttagtc tctccaggag gtattacaac
     1921 ctcttctata gaatacaaat ccataccagc atcacctttg tgagcaaaat taggtattat
     1981 agcatcatca tttaattttt ttacttttaa attgtacatc ttatatctcc tttcaacttt
     2041 ctataaatat tataacttaa atttcgacct cttgaagttt tttatttttt tgtggtaata
     2101 taattattag tgttttaaag gaggattttt tatgaaactt gtacttgctg agaaaccatc
     2161 tgtggcaaaa actatagcat catttttagg tgcaaagacc agacaagatg gttactttga
     2221 aggaaatgat tatataatta cttatgcagt tggacactta gtatcattat atgatatgaa
     2281 ggattatgat aaagataaat actctggctc ttggaaaatg aacaatttcc catttgttcc
     2341 tgaggataag tttaaattta agattgatag ttctaaaact aaacaattca acactgtaaa
     2401 aaagcttttg aatagaaaag atgtagaata tgttataaat gccactgata atgaccgaga
     2461 aggagaactt atagcatttt taatattttt actggcaaaa aataaaaaac cagtaaaaag
     2521 aatcttggta aatgaatgga caccagaaga tattacaaga ggtataaaaa acctaaaaga
     2581 tgaagatgaa atgagaaatc ttcaagctgc tggatatact aggcttatta ctgactggtt
     2641 gattggaata aatttcactt ctgttgctac attgaaatac ggaaatggga aactattaaa
     2701 cataggtagg gtaattcttc caacagttaa attagtctat gatagagata tggaaatact
     2761 aaactttgtt cctaaaactt attatgaaat agaagggcat tttaaagctg aagctggtga
     2821 atataaaggt aaatatgtta agggtaaaga aagtaaattt gatacacttg aagatgcaaa
     2881 taaaattata gcttcaatta catctgaaac tggtaaaata ctagataaaa aagttactat
     2941 gtcaaaggaa tatgcaccaa aactttttag tttgacatca cttcaaggat atataacttc
     3001 taagtattcc aattttacat ctgataaggt tttaaatgtc tgtcaatctc tctatgaggg
     3061 taatggtaag ggtggataca taacttaccc tagaactgat tccattttct tagaagaaag
     3121 tttggcttca aaagcttctc aaactttaga taaattaaag gttggtcttg aatatgaaaa
     3181 taaaattaaa ttttctaaaa ctaaaagagt ttttgattct tctaaagtag actcccatag
     3241 tgctataatt ccaacttata taattccaaa aagtttatct aaggatgaac aattagttta
     3301 tgatgccata aaagatagat ttgtagcaaa ctttatgcct cctgctgaat atgagaatac
     3361 agaaattaag actgaagtag ataattgtac tttcttaaca aaaggtaagg tgcttaaatc
     3421 aaaaggatac cttgaggtat ataataagga agaaaaaaac gatttacttc cacttgtaaa
     3481 taaagatgat gttgtagatg tgttagaaat aaaaccatta actaagcaaa ctactccacc
     3541 taaaccatat actgaggaca cccttttaaa ggctatgaaa aattgtggta aaaatgtgcc
     3601 tgaagaagat acaacagtgc tatctggata ttcgattgga acatcagcca cacgtgctga
     3661 tgtgttaaag aagataagtc aagtaggcta tgtaaagaaa aaagggaaat cttattctat
     3721 aacagacctt gggaaaaatt tagttgaaat ttttcctgtt aaagacttat ttgatgtaga
     3781 ttatactgga aaacttgaaa aaagtttaag cgatattcaa aaaggaaagt atacaagaaa
     3841 agaatatctt actaatatca ttagttttat atatcaaaat gtcaatatta taaaacaaga
     3901 tgcttcaaaa aatataaaca cagaagcata tactttcgat tcaaaaacta aaaaatttac
     3961 taaaacaaaa gaaaaaaaac agaaaaaaga tgtaactaat actgaaaaag aagttgctat
     4021 atcaaaggat tctaataaca aaaaagaagt taaaaatgat gatgaaaatc aatctcttgg
     4081 caaatgcccc atttgtcaag gtgatgtact agaatttgac aaaggctttg cttgtaaaaa
     4141 tcataaagaa tgtaaatttg ttatttggaa aaatgataag tatttaagtc tttataaaaa
     4201 gaaagttaac aaaacaatgg tcaaaaatat tttaaaaaaa ggtgaaacta aagtaaaatc
     4261 tttaactgct aaaaacggta ataaatttga tgctacatta aaatatgata aaaatccaga
     4321 taccggctat ttcaattgga aaatagagtt tgacaactaa atattcataa gaaaagaaat
     4381 agcagtagta taataatcta tattatatta ctgctatttc ttttcttatg aagttttaac
     4441 ttttttaata gtgactttta caatcacact ctaacctaat ttctttacta tttctgataa
     4501 ctttaatgta tgttcatcta ataaagttag ttcctcttca gaaagattag ataatttttt
     4561 tactagagat tctttgagaa tagcttttac tgcatcaaat aatttaaatg ctttatccgt
     4621 taattcaacc ctaagaatcc ttctatcttt tgggtcagga aatttattga ctaaaccatg
     4681 ttccactaat ctgtcaataa tcggagtcat atttgatttt aaaattccta aattagaagc
     4741 tatttgagaa attgatgatg aatttgatgt cataagataa agaattacct tagcatgtga
     4801 tggagccatt ggacattctt caaaataagc tttcattata tcagagttat tttgaaactt
     4861 ttttaacaaa tcgctttctt taaatatatt attttcaagc acaaataaaa aatctaaaaa
     4921 agagtccgct attttaagta tattgttgtt atccatattt gtaacatccc ttcaatagat
     4981 aatataataa aacattgttg tttaatatag tataaattat aaactattaa taaatttaaa
     5041 acaagaaaaa gttattgact cataataatt ataaatttat aatcaaatta gagaattata
     5101 aattgccaat aaagggaagt tttttaatta gtctaaaact aaacttaaat tataagacac
     5161 tttaaattct acaacaagct agtgtgcaat atataatagg aggagatatg aaaagatatt
     5221 taatagtttt cttaatgtgt agttcactgt ttttagttgg atgtggaaaa acagaagaat
     5281 ctgaacctga gaaaccaata gcagtttctg ttcaaaaagc aataggtgga gaaattgaaa
     5341 acacaaattc tttctcagga actacaaagg ttaaagatga aacagctgtt actgcacaga
     5401 ctgttggcac agttcaagaa gtgtatgtaa aacttgggca aaatgtaaga aaaggagatg
     5461 aattattgag tataagcagt ccagagctag aaaatagtgt aaagcaaagt aaagcctcac
     5521 tagatttagc aaaagcaagt tattcaagtg ccactggtgg ttcattagag gcacaagtaa
     5581 atcaggcaaa aacagctctt gacaatgcaa agattcaata tgaggagtct caaagaaatt
     5641 atgacaataa taagattctt tatgaacagg aagtcattag tttagaccaa tttaaaaaaa
     5701 tagaattttc tttagagcaa acaaaacaac agttagattc tgctcaaaga gcatacgata
     5761 cagcaacttc aaaaagtata cctcaagcta aagcacttgc taaaaaacag cttgaccaag
     5821 ctcaagtatc atataattta gcaatgagta atttagacaa attaacatta acatctccag
     5881 tagatggtac aataacagct aaaaactttg attcaaagga aatgataaca caatcacaac
     5941 cagcttttat tatttctaat cctaatatac tagaagttga tttaaatgta gcagaatcag
     6001 atataggtaa atttaagaaa gatggaaatg tagatgttat aattgaagac caaaggattt
     6061 taggaaaaat agattatgta ccttcagtag ttgaccctca gacatcttta tatcctgtta
     6121 aagtacttgt aaataataca aacaacaaat ttaaggcagg tatgtctgct caagtaaact
     6181 taagtgttga aaaagaaaat ggtgctgtta cagtacctaa aaaagcaata tttgaagaaa
     6241 atggtaaaaa atatgtatac atagcaacaa aagacaatat agcaaagaaa cacttggttc
     6301 aaactggaat tgtaacagag gataaaatag aaattaaaag tggtgtaagt gataaagata
     6361 cagtgattat tggagggata agtcttattt ctgacggaac taagatattt cctgtagaaa
     6421 aggagaagta gactatgaat ttaacacaga cttccgttaa acgtcctctc acaatcataa
     6481 tggtcttttt agtattaata gtttttggtg gtattggata taaaaaaatg tcaataaatc
     6541 taatgcctga tatagaaata ccagttgtaa tggtcatgac tacttggaca ggtgctggtc
     6601 ctcaagacgt tgatgaacaa gttagtcaaa aagttgatga aagtttatct gccgtttcaa
     6661 atgtaaaatc tactatatca agttcacaag aaagtgtttc tatggtagtt gctcagtttg
     6721 aatttggaac taatttggat gaaataatga atgatgttag gtctaaagtt gatgcattac
     6781 agaccagcct cccagatgat gcagctaaac caacagtttt aaagctggat atgaatgcac
     6841 aggctatagg tcaacttgtc atatctggag gaaatgaaaa tagttcacaa gccttaagaa
     6901 aatacgctga agatgtaatt cagcctaaaa tagaatccat agatggtgtt acttcagcag
     6961 accttaaagg tggagaaaaa gcacaggtta atgtaatagc tgacccagct gttctttcaa
     7021 attatggagt tagtttatcc actataaaag gtgtcttatc ctctagtaat aaaacattcc
     7081 cttatggttc aattactcaa ggtgaggata aaatagtttt aagagcgatt gataaattag
     7141 aatccctaga tgatataaaa cagattcaaa ttcctgtaaa aggaggaaat acagttagat
     7201 tagataatct ttgtagtgta gattatggat atgcagacaa agatagtatt tatagataca
     7261 atggaaaaga cagtttggta atagatattt ctaaacaaca agatgccaac actgtaaaag
     7321 ttatgcagag tgcatacaaa tacgtagatg aattgaataa ggaaaatcct caatttaaaa
     7381 ttaaaattgc taatgataca agttcataca taagtgaatc aataaacagt gtaatgagca
     7441 acttgcttat aagtgctgtt atcgcattta ttgtaatatt tgctttccta aaaagtgtaa
     7501 gagcttcact agttgttgca gttgcaatac caatttctat aataggtgct atagcaattc
     7561 tctactttac tggtgaaagt ttaaatctta ttactgcaag ttcattggta atttcagttg
     7621 gtatggttgt tgataatgct acagttgtaa ttgaaaatat atttaaatat aggaaaagtg
     7681 gtagattgag tcttgatgat tgtgctattg agggaacaag aactgtaaca aatgcaatac
     7741 ttgcatcaac attgaccaca atagcaatat tcttacctat catgtttaca gaaggtatag
     7801 ctaaaataac ttttggggca ttaggtaaaa cactaatagc ttcactagca ttctccttta
     7861 taggtgcaat tacactcgtt cctagtgtat ttgcaaaatt aagcagcgga aaaaatagtc
     7921 aaaagatgca agaaaaagat agtcctatat ttgataaggt aagtgaagca tataaaaaat
     7981 tattaagtgt atgtttgaga catcaacgct tagttgtaat atcaagttta cttatttttg
     8041 tagcttcctt atttggaatg ggatttatag gtatggactt tatgcctgca gcagacaagg
     8101 gtgaattatc tatttctata gaacttccaa aaggtcttag cctagaatcc aatgattact
     8161 atgtatctat gactgagaaa aaagtctcag atattccaga aattaaaact ttaataacaa
     8221 ctttgacatc agattcaaat aatagtaaag caagtatagc aattgaatta gaatctcaaa
     8281 aaaatagaaa aagaactact gatgaaatag aaaaagagat aattgataga gtggctactg
     8341 taccagattg taaaataaat gtaagtcaaa acagtagtgt tatgggtgga gctggaggag
     8401 cagacttcac attagaaatg aaaggtcctg atttagatgt attaaaaata ctgggaaaag
     8461 aagctgaaaa agaatttagc tctataaaag gatttagaaa tgttgaaact tctcttacag
     8521 atacaacaca agaagctcaa tttactatag ataaacataa ggctcaagaa tatggtgtaa
     8581 ataccgctga aattgcaggc atgttacgta cagcaataaa tggtgactcc gtaaccactg
     8641 ctactattga tgattacaaa gtggatgtaa acctaaaatt taaagcagat actattgata
     8701 gcttagaaga tataaagcaa ctaaaagtaa actctgcaac tggaaaagaa gttcctcttg
     8761 gtgccttttc agatataaaa atggcagatg gtctacaatc tatatctagg actgatggag
     8821 atttttctgt aaatataact gctacacttg acaatttaga tgctggtact gctacaaaac
     8881 tagcactaga aaaaacgaat aaaatggtaa ttcctaaaga ttactctata ggtgttggtg
     8941 gtgaaacaga aatgatgaat gaatctatgg caagtcttgg attttcaatg gtcatagcta
     9001 tagcattagt ttatatggta atggtagctc agtttgaatc atttagtaaa ccatttataa
     9061 tcatgttctg tgttccattt gcattcgttg gagttgtgct ttcgcttcta gttagtggtc
     9121 aaagtttaag tactgtcggt atgctaggta taatcttact tatcggtatt gttgttaata
     9181 atggtatagt tcttattgac tacatagagc aacttagaaa aacaaatcgt aacaatgatt
     9241 taattggttt ggtttcaatt ggttgtgcag caagattaag accagtctta atgactacag
     9301 caacaacaat tttaggtatg ttgccaacag cactatctct tggtgaaggt ggagaaacta
     9361 tgcaaccact agccatagtt ataatgggtg gtctaactgt atctacactt ataactttgg
     9421 tgcttatacc tactatatac ttaatatttg ataaatggga aaataagttt tcagacaaaa
     9481 tgcctaaaat atttggtaag ataacagata aaataggaag tataaaacgt aaaataataa
     9541 agaaaccaaa attgaaagct aaagtttaaa tagaatggag ggtgattgta ttgaataaaa
     9601 aaatgagcaa aatagttgca attggctgtg gtgttggtat aataactgcc aatttaatcc
     9661 cagtttacgc agataataat acttcttcta taaacaaagt tgataattct attttaagtg
     9721 actcaaataa aagaacatct gaaaaggaaa ttttgactgc tagagaagct gttagtgctg
     9781 cacttaaaaa tagtgaaaaa ttaaaaatga aatcagaaga aataaaaatg ttaaaagaaa
     9841 agttagaagt acaagatgag tttgatagtt ttactggaag tgacaactcg tttccatacg
     9901 accaaattgg acttcttaaa aatcaaagtg aacaggctaa aggctttatg gaggaccaaa
     9961 tagcaaatga tattactaat aaatttaacg atttagtttc aagagaaaat gagctagata
    10021 aaataaaaaa taatcttgaa ataaaaacta aagaaattaa agatatgaaa ttaaaaaaag
    10081 atttagggtt agtaacatct ttagaaactg aatcagctga acttgaactt caaacactac
    10141 aaaatactca aaaagctaaa cttcaagaac taaaaaacaa tcaagactat tttaagttat
    10201 taactaatat agatttaaat aattatcaat tggataaaga atatagattt gaatctttta
    10261 gagtaggtgg ctcagttgat tcatatatgg aaggtaaggt taatgaatat ttaaaatacg
    10321 accaattgat tttagaacgt acagaagaaa gctttaatga taaagatgag aacaaagcag
    10381 atttaccaga tagacctaac cttacaagac cagttgctcc tacaaaacca gagcaaggta
    10441 acctaactga tgatgaatac aaggttctta tggataagta tgaaaaagat tatgatagat
    10501 ataaaaaaga agttgaagca tacaatcttg aaagacagac ttatgctgct ggccttacta
    10561 cttatgcaaa ttatcttcaa caaaaattta atactgaaaa tggtctagta acattagaag
    10621 acagtaaaaa agctcttaaa aaagggttaa ttgatagcta tgctcaatta cttgctttag
    10681 aagatacaat tcagattact aaaaaacaac ttgatttatc agaaaaacaa ttaaaaaata
    10741 ctaaattaag atatgattta ggattaatta ctctaactga ttataaaaaa caagtggtaa
    10801 gtaatgaaga tgctaaaaat agctatgaca ctcttattgt gaattataac tcactaaaaa
    10861 atggtataga aaaaccttgg atacttaata ctggaaaata attctggtaa atagaaagat
    10921 tactttaaca tacgtttgat taaaaaatag ttatgcatac tcgtggcttt agtcatggaa
    10981 gattcagaag gcaaataata gaaatagatt agtaaaaata tatttactta taaaactgta
    11041 tacttttata gaggctatct caaaatagag ataagcctct tttttattgt ttaaattata
    11101 aaaatatatt tgattccata caaaaagagt gccttatgaa ctaaaaagtt cattttgaga
    11161 caccctcaaa agcttaactc taaatttaat tattttttat caaatgtctc atctatttta
    11221 catctcacca tgttaacaaa ttcagaaata ttatatcctc taagtttgca tccacattta
    11281 ggacaataat ccagtttcct agataccaaa gccctacaac taggttctgg acatcttatt
    11341 tttagactct catctgctac tttaaatcca catcgtgggc atatactacc tggacgtgat
    11401 gatacttcct ttccacattt aggacacttt gtcaacttta tcccctccag taaactcaat
    11461 ttaattgata gttgaaattt ctctctacaa taatatatgc aatataatta aatacgtttc
    11521 acttacaact atataagtta aatttttata ataaaaatcc cctatattca atttacaaat
    11581 acttaatttg atacattgaa caatagggga ttttattttt atttagttac atattttgca
    11641 gtctattatt atctaggatt ttttatagat gcttgagctg ctgcaagtct agcaattggc
    11701 actctaaatg gtgaacaaga tacatagtta agtcctacac tataacagaa ctctactgaa
    11761 gatggttctc ctccatgctc tccacatatt cctagtttta attctggttt aacttctcta
    11821 cctaatttag ctcccatctt aactaactta ccaacaccat tttggtctag tacttggaat
    11881 gggtcttttt ctaatatttc ttcatctaca tattgaccta agaatttacc agcatcatct
    11941 cttgaatatc caaatgccat ttgagttaag tcattagtac caaaactgaa gaagtctgct
    12001 tcttgtgcta tttcatcagc agttaaacaa gctctaggta tttctatcat agtacctaca
    12061 gtataaggaa cttctatacc ttcttctttt attatagcgt caacagtttc tactatcatt
    12121 tttcttatta tttttaactc atttacttct ccaactaatg gaaccattat ctctggagaa
    12181 actttaacac ctgctttgat tgcttctata gcaccttgta ttatagcttt agattgcatt
    12241 acacatattt caggataagt tattgcaagt ctacaacctc tgtgtccaag cattgggtta
    12301 aactcatcta aatcaactat tctcttctta atatcactta cttttattcc catagatttt
    12361 gaaagttctt ctatagtctc atcatcatga ggcaaaaatt catgtagtgg tggatctagt
    12421 aatcttatat taactggttt tccatccata actttaaata actctacaaa atcttctctt
    12481 tgcattggta atattttttc aagagctttt tctctttgtt ctactgtatt agataatatc
    12541 atttctctaa ctgctggcaa tctagcttca tcaaagaaca tatgctcagt tctacataga
    12601 cctatacctt ctgcaccaaa ctctatagct gcacgagcat ctctaggatt atctgcatta
    12661 gttctaacca tcatacattt gtgtttgtct acccagttca ttaatttttc aaaatttcca
    12721 gtcaaagata cttctgtttt cttaacatct cctaggtaca catttcctgt agaaccatct
    12781 atagaaatgt attcaccttc ttttataact acatcatcaa gtgctcttat ttctttatta
    12841 aactcatcaa cttttatttc tccacatcca gcaacacaac atttacccat acctctagca
    12901 acaactgctg catgtgatgt cattccacct ctagctgtaa ggattccttc tgctttaacc
    12961 attccttcta tatcttctgg agatgtctct agtctaacta aaactacttt ttctcctttt
    13021 tcatttgctt ttactacatc atcagcattg aaataaactt taccacttgc tgcacctggt
    13081 gatgctggta aaccttttgc tataaccttg gcttctttta atgccttatc ttcaaatttt
    13141 ggatgtaata attggtctaa ttgattaggc tcaattctca tgatagcttc tttttcatca
    13201 attattccag cttcaactaa atcaaccgct acatttattg ctgctgctgc tgttctctta
    13261 ccatttctag tttgtagtat atataatctt tcattttcta tagtaaactc tatatcttgc
    13321 atatctttat aatgaccttc aagtatatga gtaattttta caaattcatc gaatacagct
    13381 ggcattacat ctgcaagagt tgatatattt tgaggagttc ttatacctgc aacaacgtct
    13441 tcaccttgtg cattcattaa aaattcacca aataatttat tttctcctgt agctggattt
    13501 ctagtaaatg caacacctgt accactagtt tctcccatat taccaaatac cattgattga
    13561 atatttactg ctgttcctaa gttatgagct atatcattca atttacggta tacgattgca
    13621 cgaggattat tccatgatct aaatacagcc tctattgcaa gcattaattg ctcttttggg
    13681 tcttgtggga aatcattttt tatttctttt ttataaattg ctttaaattc ttttactatt
    13741 tcttttaaat catcagttgt aagttctgta tcaactgtgt atccctttgc ttcttttact
    13801 ctgtctaata cgttttcaaa tttatatttt ggaacttcca tagcaacatc agaaaacatt
    13861 tgtatgaatc ttctgtaact atcatatgca aatctttcat tttgtgtagc ctctgctaag
    13921 ccaacaacac tattgtcatt aagacctagg ttaagaattg tatccatcat tcctggcata
    13981 gagaatactg caccagaacg aactgatact aataatggat tcttattgca tcctaatgtt
    14041 ttatttaagt ctttttctaa agcagctaaa tgctcttcta tttcttttat tatctctgct
    14101 cttatacttt cattgttaac ataataatca ttacatgctt ctgttgttat agtgaatcca
    14161 ggagggacag gtaagcctat cttagtcatt tctgctaaat tggcaccttt acctcctagt
    14221 aaagatttca tgtctttgct tccttcacca aaactataaa catacttagt ttccattgtt
    14281 aaatccccca ttaatctttt tattttaatt tatatcattt ttattaatag acattattaa
    14341 atttctattt ctttgtatat ctttagacca ttttctttca ttatgtctaa aattatacct
    14401 gctgtttctt ctattgcctt atttgaaacg tttattactg ggcatccaat tcttttcatt
    14461 atctcttctg aataatctaa ctcctgaagt attctttcta aattagcgta gtttgcttta
    14521 ctggacaatc ctaaagcttt taatctttgg gttcttatct cattcagctt ttcaggtgaa
    14581 ttagtaagac ctattatttt tttagtatct atctcaaaca cttctttagg aattggtatt
    14641 tctggaacta atggaacatt agctactttt atatttttat tagctaaata catactcaaa
    14701 ggagttttag atgttcttga tattcccact aaaattatgt ctgcttgaag aacacctcta
    14761 gggtcttttc catcatcata tttcactgca aattctatag cttcaactct cttaaagtaa
    14821 gattcatcta attttctaat tataccagct tctcttttag gttttcttcc tgttctcttg
    14881 cttatttctc ttagtatatc tgtcattaaa tctatacaac taagaccttc tctttcgcaa
    14941 tatctttcaa caatactgca taattcttca tcaactaatg tatatacaat taaagcgttt
    15001 tcagcttttg cattctccaa agtttcaagt agtactcctt tattaatcat gtatggaaat
    15061 ctttttattt cataagtttc attcacataa aactgagaca tacatgcctt tgcaacttgt
    15121 tgtgcagtct cccctactga atctgatact gcatatataa ttaggttttt caccagcata
    15181 cctccttaat tgtcaactat ttctaagaat agcttagtta tgttggtttt tgatattctc
    15241 ccaacaactc tcatatgatt tttgtcttct cccttatatt caacaatcgg aatcgaatct
    15301 acttcatgtt ctattatttt tcttgaagct aataaaacac ttgctccttt agttaaagtg
    15361 actacatttg gagttcttgt cattatcata cctattggca ttttatttat atcagaacct
    15421 cctatagttg cttttagcaa gtcttttctg gaaacaactc cacataactc ttcattctca
    15481 tctataataa ctatactccc tacatcagat aaaaacatag tgactattac atcatatata
    15541 ctttcatcct tcttagctag tacaggcatg ctcattatat cctctactgt tttttctttt
    15601 acacttttac caattaaatt tatttcacta actcctgaat aaaaatatcc aacttttggt
    15661 cttgcgtcta atattcctgt cattgttaat atagctaaat cagatctaag tgtagcacga
    15721 gtcacattca agctggaggc aatactttca ctcgttattg gttcattttc cttaactata
    15781 tctataattt ttagttgtct ttcattaagc tgaataataa tcaccttctt tcattgtgct
    15841 atacttttta tcttttcgca tcttatatag tatattatat aactatatat accattctgt
    15901 aaacagattt tttattgaat acgatatatt ttttactaag ttctctcgct taaagatatt
    15961 tattatatat taatggggga tattccttta attaatagaa ctatattagt attacagtta
    16021 atattataat acataattgg tcattttaat tcattttata ttaaaatttt taataatatt
    16081 gtttcaatgt gaatataaaa ttgcagaact aattcaaaat aatttttacg actacaaata
    16141 acctataata tacttttaaa gaaagtatcc taacaagaat atataaaaat ttaaaagggt
    16201 tgatttaaaa ataaccatca acccttttta ctaatatcta tttatattac catcaaatct
    16261 tacccaaata ttttttcttg caattgtctt aaatgatata aagtagtatc tttttctatc
    16321 tctaccatat cgtaagttat aacttcacct tttttaatat cttttacaac tttagtcttt
    16381 ttacttatca aaccaatagg tacagcattc atagcctttg ctacatcgta tttttctata
    16441 gtaccatagc atgtatatgc tccatagcca tccataaact cacctttttt caaatctttc
    16501 ttagctatag tcataacttc tgctactagt ccagctttag gtactattgt agccttatgg
    16561 tctaagactg ccatagctgc tgataaagga gtctctaaac tacataaatg atatggtcta
    16621 tataatatgt aattaggtcc atcacccata cttaaatatt ttagttcatc attaactgct
    16681 tttaatttat gggctactac tacgaaaact ccaggtgcta taccatttac aaaatcaact
    16741 acaccataat tatctaatac tccaccttcg ctttttaatg catatttctt aggtacttca
    16801 ttaactgtag cttcaatacc atgaccacct cttacatcag gcacaaatcc agttgcatta
    16861 cacattaaag ccatttctac cattgtttta gttccttctt taaaagaagc tatcatatga
    16921 ggtgaagctc cttttctttc tgcttcttct ctaactgtat caggattaca atctaaatct
    16981 aatttattat ttttaccttt acctatcact ctaacttcaa accccattgc atctgcaaaa
    17041 tcaaataatt ccattactgc acctggctca tctcctgcag aacctgtaaa tattactcca
    17101 gcatcatctg ctaatttttt aagtattggt ccaacaacac aatcagtttc agcatttaac
    17161 ataactatat gttttttatt taaaatagag tttaatgcta tctctgcacc aattgcaata
    17221 cctccagttg catctataac tacatctatt gacttagttt tacaagccac aagaaaatca
    17281 ttacatgtca atacttttcc ttcttgtaat tttatttctg catccttttc atttgttaca
    17341 ttatctataa tttcttcatc tattcctgca tcagtaaaag ctttatgagc caactccaaa
    17401 tttatatcta caacaataga agcttcaata cctttcatat ttgccatttg gcttaccatt
    17461 ccatttccca tatgcccagc tcctataaga gctactttta tttttttacc ttcctcttcc
    17521 aattttgcaa gttttctgtt taaatctaac ataccaattc ctcctgttat aataatttta
    17581 ttttcaaatt aagaaatagt tattaaatct ccaatagtta tatctggatt tcctatttcc
    17641 acatgtattt ctcctggtaa atttacttca cattttccat caaatttgat tgtacaatgc
    17701 ccaatttctc taagagtctt ctgagcaata tcaccaactg aaactataca ataatctcta
    17761 ttccctatag taagtgtatc tcctatttca acatcacttt ttaacgttgc tattgaatga
    17821 attacagata tatcctttaa gtcgtcatca ttaatggttt catcatatat aataagacaa
    17881 ttgctttcat ccattaactc tttaactaaa ctgcctatcc cacttatctt aacttcatat
    17941 ttcatgacat tcctcctgat aatttatatt tatattgagt taattaaaag aaacatttat
    18001 tttttctttt ataaatttta tagcttgtac aatactctct tcatctttaa atttttgctc
    18061 tgcactatat atatctaatc cttctatttc ttcaatctct ttaaatttag ccattactgt
    18121 acgtcctttt aaaatttctc caaactttat aaacccatct gaatctgaag atataatggc
    18181 tatacttcct ttagaaaaat agcttttctt tttgcctgta gacactatat cacccttttt
    18241 tttagctcta tttaaagttt taaaatacaa tttattctgc ttcattataa atatagtatt
    18301 taaaatataa gcaacaaata aaatcactaa taatttcata tttatacacc ttccaaaaat
    18361 cacattattt ttaaatctgt ataacaacta taaatgctgt acaatagtta tataaggttt
    18421 ttaagtaaca cctttttaaa ttctaaaaaa gttctacatt tacttatctt attcgttaat
    18481 tttacatctt ggcctatctt taaaacttct tcataaattt ttactaataa gtctgagtct
    18541 atcttattct cacatggaaa cattgtcata agaattattt ttatacttct atttgcatat
    18601 tctattggtt cttctaaaat tccaactgcc attaaaaact tatctgattt ttcatttaca
    18661 gaatgaggaa ataataaacc tttatcaaat actgtgggag atttttcttc tctattgact
    18721 atattttttc taaacttatc atcaatgcat cctaaatcca taagatggtc catcattttt
    18781 tctaatgaag caagtatagt cttttcattt aatatcataa atttatcttc atctaacaaa
    18841 ttatttatta gtaaatttgt agaattagta gtgtcaatat tcccttctct taggcacaat
    18901 actgttttta attgttctct tagtttgttt tcatcaaata ttgtatttat ttttaatact
    18961 attgtattta tatttgatgt gtctaaatca atagttgtaa aaactatatc atattcatct
    19021 aagttaatat ttctcaaatt aaaacttgaa agagtatcaa ttttaggatt atttcctatc
    19081 agtttttcta ctcttatttt caatagtttt gctgttccta gacctgtact acatataatt
    19141 gctatttttt ttattgaata gaatctactg ctatttcttt ctaaatatcc actgaaatgg
    19201 attgctatat atccaatctc atcttctgaa acttctaagt tatacttttt ctctattact
    19261 tttcctgcta tttgtgctaa tttaaatgga agtatataat tttgcttaat ctcttctaac
    19321 aaaacatttt ttaactttat attaaataat agcctgttta aagtaaaact aagatgatat
    19381 cctagaccta ctcttaattc atcctcattt ataaaaatac ccatatcgac atatatttga
    19441 ttaaatatat tttccatcaa ctcatcaatg tttttactaa ttctactact atttaaagca
    19501 cattctgatg ctggtgcatt tccactaact aacggtatag ttaaataaat aatttcttca
    19561 tcatttaaag tacattcaaa cattcctgat attatatgtt ttatttccct agcaataaag
    19621 tattcatcat atgatttaag taaatcaaac tttacatcat aatcttttac tttcttttct
    19681 tcttttactc tatagactaa aactactatg tagttaataa cttctcttaa catttcatct
    19741 gtaacataaa aattattttt tttaaataaa gtcaatagtt tttcttctaa atttatgatt
    19801 tcttcttttt tgattccttt aaaatacttt gaattactga aatctttcct tgagttttta
    19861 tacaactgat ttaatataaa cagtctaata tcaagttcat ttccatttaa tttcatacct
    19921 gtattctgtt ttttaatcaa gtttaaatta tatgaagcca aaactttttc tacatactgg
    19981 aaatcattta ctaaagtagt tcttcctaca cacatctcat cagctaaact atcaagtgta
    20041 ataaatccat ctagttctat caagtaattt agtataaact ctactctatc ttcttttgaa
    20101 tttaatgaaa atacattttt tctattcata tcaataatct tattgagtat ctgctcatct
    20161 tttatttcta gtttatagcc ttgacccttt atatatttga ttactgctat atcattacct
    20221 aaatctttat tcaattgttt tatatacgtc cttacacttc tagttgtgac attcaattca
    20281 tttgctattg agttaatact cacaaactct tttttactac acataatcaa tatcttaaat
    20341 atcttgcggt caatagaagg aattttctca gttacactca ttttgtatct cctccttgat
    20401 ttcattctag tacaaatttg aaaccaaatt aatacataaa atttcacttt aataaaggaa
    20461 aatttagtat taatctaact cgataattac agctaattaa tagtataaaa gctagtcttt
    20521 cattaacaaa aaatcttgac tagcttaaat ttatatttac aattttatta attaattcca
    20581 agccttatat tgacattaaa tattatctca atgcaaatac tgcaactcca tatgcaataa
    20641 taacagctat tggaccagtt attaaacgag agtaaaataa agctggaaca ccatactcta
    20701 cagtttctgg ttctgcttct cccaaactta atcctactgg tacaaaatca catccagctt
    20761 gcccatttat tgcaaataaa gctggaagtg ctaaatatgc tggtattgca ccaagaccaa
    20821 tttgtgtacc tacaagagtc cctactactt gagctataac tgcaccaggt cctagtattg
    20881 gtgataagaa tggaagtgtg caaattactg atataatcaa taatccacca atattacctg
    20941 caagtggaga tataactctt gcaatccagt ctcccagtcc agatgctaaa ataattccca
    21001 taagcatact tacaaatgcc ataaatggta ttacgttatt cattaccatt tggatagtat
    21061 ctcgacctgc atcataaaat tttgatacta cttgccctgc cccttgacca atagaaagta
    21121 ttatgttctt tttagcatat tcaccttgtg cttttgactt aacctcatca taattatcag
    21181 gctttctaat agaactctta ttttcgcttt tattttcttg agatttttgt ggcatatctt
    21241 ccccatctac aacacttata cagttaggat taacatctga tacataatat tcttctgtta
    21301 taaattttgc taaaggacct gtttttccaa ctggatttac atttattgta ggtatttttt
    21361 tctttggata aactccacat ctagcagttc caccacaatc aataataact actgctactt
    21421 cttcatcaga aactccagtt ttaaatccat ctacaatttc acaacccagt agttctttta
    21481 tttttaatgt tacttcatgg ataccaccag cagtcattga cagtatctta tttctattcc
    21541 cttctttttt tatatacaaa ggacctcccc agcctgaagt tcccttttct atttttaata
    21601 ttttattctc ctccatttta tctacctcct aagccttatt tgttgctcta ttttttcttg
    21661 ttagaaaagc atacattttt tctgttacta tacctcttat aaaaattaca attagaccaa
    21721 ctataaaata ccacaatgcc aatgtagtag tttctttacc taaagtagtc aaacctgcag
    21781 atattcccaa ccatacaaaa agttctcctg catttgcatg tggaaaaaga cctgtaattg
    21841 gatgtacaaa tgaaactgct gcatcataaa atcctgcttt gtgctcttct tttaaaaatc
    21901 taccaaatgt atagcacata ggatttccca agaaaaatac tgatactaat ggaagtagaa
    21961 tatatcttgt aaaagagttc tttcctagct tagaagccca attattaact ctttcctcac
    22021 caattatctt aatcaaagag ttaatagcta ccattaatac aattagcgtt ggaagagtac
    22081 ctgaaacaag acctataaat tgttctcccc ctttctgaaa caaaccgata aaccactctg
    22141 cacctttact tagacctgta ataacgtttt ccataaaatt ataacctccc tataatatct
    22201 ttaaattttt aattttactg cttaccataa attttacaaa ttacatcttt tttctgtact
    22261 atatgctaat attgtaaatg tttttttatt aatatcattt taatataata tttttgataa
    22321 ataaatacat cttttttcaa ttttataaag gaaaaaattg tactaat
//
LOCUS       DAEPUT010000066        22180 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.068, whole genome shotgun sequence.
ACCESSION   DAEPUT010000066 DAEPUT010000000
VERSION     DAEPUT010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22180
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.068"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..237
                     /gene="tuf"
                     /locus_tag="KRL22_002697"
     CDS             <1..237
                     /gene="tuf"
                     /locus_tag="KRL22_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452162.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH1273169.1"
                     /translation="GGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTME
                     VDLINSIVVEEGLRFSIREGGRTVASGVVATIIE"
     gene            608..919
                     /gene="rpsJ"
                     /locus_tag="KRL22_002698"
     CDS             608..919
                     /gene="rpsJ"
                     /locus_tag="KRL22_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBH1273170.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            1011..1640
                     /gene="rplC"
                     /locus_tag="KRL22_002699"
     CDS             1011..1640
                     /gene="rplC"
                     /locus_tag="KRL22_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBH1273171.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1670..2293
                     /gene="rplD"
                     /locus_tag="KRL22_002700"
     CDS             1670..2293
                     /gene="rplD"
                     /locus_tag="KRL22_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBH1273172.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2293..2583
                     /gene="rplW"
                     /locus_tag="KRL22_002701"
     CDS             2293..2583
                     /gene="rplW"
                     /locus_tag="KRL22_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBH1273173.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2613..3443
                     /gene="rplB"
                     /locus_tag="KRL22_002702"
     CDS             2613..3443
                     /gene="rplB"
                     /locus_tag="KRL22_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBH1273174.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3478..3759
                     /gene="rpsS"
                     /locus_tag="KRL22_002703"
     CDS             3478..3759
                     /gene="rpsS"
                     /locus_tag="KRL22_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBH1273175.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3791..4126
                     /gene="rplV"
                     /locus_tag="KRL22_002704"
     CDS             3791..4126
                     /gene="rplV"
                     /locus_tag="KRL22_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBH1273176.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            4149..4964
                     /gene="rpsC"
                     /locus_tag="KRL22_002705"
     CDS             4149..4964
                     /gene="rpsC"
                     /locus_tag="KRL22_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBH1273177.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            5000..5431
                     /gene="rplP"
                     /locus_tag="KRL22_002706"
     CDS             5000..5431
                     /gene="rplP"
                     /locus_tag="KRL22_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBH1273178.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5433..5636
                     /gene="rpmC"
                     /locus_tag="KRL22_002707"
     CDS             5433..5636
                     /gene="rpmC"
                     /locus_tag="KRL22_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBH1273179.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5660..5914
                     /gene="rpsQ"
                     /locus_tag="KRL22_002708"
     CDS             5660..5914
                     /gene="rpsQ"
                     /locus_tag="KRL22_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBH1273180.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5940..6308
                     /gene="rplN"
                     /locus_tag="KRL22_002709"
     CDS             5940..6308
                     /gene="rplN"
                     /locus_tag="KRL22_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBH1273181.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6332..6637
                     /gene="rplX"
                     /locus_tag="KRL22_002710"
     CDS             6332..6637
                     /gene="rplX"
                     /locus_tag="KRL22_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBH1273182.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6667..7209
                     /gene="rplE"
                     /locus_tag="KRL22_002711"
     CDS             6667..7209
                     /gene="rplE"
                     /locus_tag="KRL22_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBH1273183.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            7227..7412
                     /locus_tag="KRL22_002712"
     CDS             7227..7412
                     /locus_tag="KRL22_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBH1273184.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7445..7843
                     /gene="rpsH"
                     /locus_tag="KRL22_002713"
     CDS             7445..7843
                     /gene="rpsH"
                     /locus_tag="KRL22_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBH1273185.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7874..8416
                     /gene="rplF"
                     /locus_tag="KRL22_002714"
     CDS             7874..8416
                     /gene="rplF"
                     /locus_tag="KRL22_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBH1273186.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8452..8820
                     /gene="rplR"
                     /locus_tag="KRL22_002715"
     CDS             8452..8820
                     /gene="rplR"
                     /locus_tag="KRL22_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBH1273187.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8841..9350
                     /gene="rpsE"
                     /locus_tag="KRL22_002716"
     CDS             8841..9350
                     /gene="rpsE"
                     /locus_tag="KRL22_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBH1273188.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9365..9550
                     /gene="rpmD"
                     /locus_tag="KRL22_002717"
     CDS             9365..9550
                     /gene="rpmD"
                     /locus_tag="KRL22_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBH1273189.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9583..10026
                     /gene="rplO"
                     /locus_tag="KRL22_002718"
     CDS             9583..10026
                     /gene="rplO"
                     /locus_tag="KRL22_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBH1273190.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            10070..11338
                     /gene="secY"
                     /locus_tag="KRL22_002719"
     CDS             10070..11338
                     /gene="secY"
                     /locus_tag="KRL22_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBH1273191.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11355..12005
                     /locus_tag="KRL22_002720"
     CDS             11355..12005
                     /locus_tag="KRL22_002720"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBH1273192.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            12006..12752
                     /gene="map"
                     /locus_tag="KRL22_002721"
     CDS             12006..12752
                     /gene="map"
                     /locus_tag="KRL22_002721"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBH1273193.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12774..13043
                     /locus_tag="KRL22_002722"
     CDS             12774..13043
                     /locus_tag="KRL22_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HBH1273194.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            13081..13299
                     /gene="infA"
                     /locus_tag="KRL22_002723"
     CDS             13081..13299
                     /gene="infA"
                     /locus_tag="KRL22_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBH1273195.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13335..13448
                     /gene="rpmJ"
                     /locus_tag="KRL22_002724"
     CDS             13335..13448
                     /gene="rpmJ"
                     /locus_tag="KRL22_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBH1273196.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13601..13972
                     /gene="rpsM"
                     /locus_tag="KRL22_002725"
     CDS             13601..13972
                     /gene="rpsM"
                     /locus_tag="KRL22_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBH1273197.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            14008..14406
                     /gene="rpsK"
                     /locus_tag="KRL22_002726"
     CDS             14008..14406
                     /gene="rpsK"
                     /locus_tag="KRL22_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBH1273198.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14438..15061
                     /gene="rpsD"
                     /locus_tag="KRL22_002727"
     CDS             14438..15061
                     /gene="rpsD"
                     /locus_tag="KRL22_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBH1273199.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            15139..16086
                     /locus_tag="KRL22_002728"
     CDS             15139..16086
                     /locus_tag="KRL22_002728"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBH1273200.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            16107..16448
                     /gene="rplQ"
                     /locus_tag="KRL22_002729"
     CDS             16107..16448
                     /gene="rplQ"
                     /locus_tag="KRL22_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBH1273201.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16568..17401
                     /locus_tag="KRL22_002730"
     CDS             16568..17401
                     /locus_tag="KRL22_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH1273202.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17389..18255
                     /locus_tag="KRL22_002731"
     CDS             17389..18255
                     /locus_tag="KRL22_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH1273203.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18249..19052
                     /locus_tag="KRL22_002732"
     CDS             18249..19052
                     /locus_tag="KRL22_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBH1273204.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            19084..19815
                     /gene="truA"
                     /locus_tag="KRL22_002733"
     CDS             19084..19815
                     /gene="truA"
                     /locus_tag="KRL22_002733"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH1273205.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19935..20366
                     /gene="rplM"
                     /locus_tag="KRL22_002734"
     CDS             19935..20366
                     /gene="rplM"
                     /locus_tag="KRL22_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBH1273206.1"
                     /translation="MKSYIAKPTDVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20395..20787
                     /gene="rpsI"
                     /locus_tag="KRL22_002735"
     CDS             20395..20787
                     /gene="rpsI"
                     /locus_tag="KRL22_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBH1273207.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            21246..21998
                     /gene="cwlD"
                     /locus_tag="KRL22_002736"
     CDS             21246..21998
                     /gene="cwlD"
                     /locus_tag="KRL22_002736"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HBH1273208.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8909 a         2593 c         4550 g         6128 t
ORIGIN      
        1 ggtggaagac atacaccatt ctttgatgga tatagaccac aattctattt cagaacaaca
       61 gacgtaacag gagcttgtaa gttaccagaa ggaatagaga tggtaatgcc tggagataac
      121 gtaacaatgg aagtagactt aataaactca atagttgtag aagagggatt aagattctca
      181 ataagagaag gtggaagaac agtagcttca ggagttgttg ctacaataat agagtaatcc
      241 tttactaaac taatggattt aatataaaaa aagagggggg taactcctct cttttttgtt
      301 ttttgttgac aagtagcgct aaagcatata tactaaacta gtgccttgag acagattaac
      361 aatcaagttt aaggttatga tgttgtaata gaaaataaaa ttgaaaaaaa cagaaaaaaa
      421 cttgaaaaaa tgtaacagat gatataaaat ataatagtgt gcttgagaga ttaagaaaat
      481 aataattaaa tcctagtgaa atacgaactg atatcgattt aaaagttaca acacacccgg
      541 agcagtgtat cggtattggt tgtacgcaac ttgaaaatta aacacgtgat aaaggaggga
      601 aaacaaaatg gctaagaatg aaaaaataag aataagatta aaatcatatg atcacaaatt
      661 attagatttt tcagcaggta aaatagttga aactgctaaa aaggctggat cacaagtttc
      721 aggacctgtg cctctaccaa cagaaaaaca agttgtaact atattaagag ctgtacataa
      781 gtacaaagac tctagagaac aatttgaaat aagaactcat aaaagactaa tcgacatagc
      841 taatccaaca cctaagacag ttgactcatt aatgagatta gacttaccag caggtgtaga
      901 tatagaaata aaattataaa aacccctaag atattatcct atagatgatt atcttagaat
      961 gattactcta aaagatgtaa tccgctgtaa gaattatagg aggtgctaat atgaaaggaa
     1021 tattaggcaa aaaagttggt atgactcaaa tattcactga taaaggtgta gttatacctg
     1081 taacagctgt tgaagcaggg cctatggtcg ttactcaaat aaaaacagtt gataaagatg
     1141 gatacaatgc tatacaaata ggttttgaag atgctaaaga aaaagcttta aacaaaccta
     1201 aaaaaggaca tttagctgct gctaatgttt taaagaaaca tttaaaagaa tttagagtag
     1261 attctgtaga aggatacaca gtaggacaag aaataaaagc tgatgtattt gaagcaggtg
     1321 caaaaataga tgttactgga ataagtaaag gtaagggatt ccaaggtcca ataaaaagac
     1381 atggacaaag tagaggtcct gaaactcacg gttctagata ccacagaaga ccaggttcaa
     1441 tgggagcttg ttcttaccca ggtagagtat ttaaaaacaa aaaattagct ggacatatgg
     1501 gaagcgtaaa ggtaacagtt caaaacttag aggttgttaa agtagatgct gacaagaacc
     1561 ttatattagt taaaggagct ataccaggag ctaaaggttc agtagtaact ataaaagaag
     1621 ctataaaggt ttctaaataa tgactaacct agagaaagga ggaataacaa tgccaaaatt
     1681 aaatgtacta aatgttagtg gacaaaacgt tggagaaata gaattatcag attctatatt
     1741 tggcgtagaa gttaatggac atgttttata cgaagttgta aaaaatcaat tagcaaataa
     1801 gagacaagga actcaatctg ctaaaactag agcagaagtt agaggtggcg gaagaaaacc
     1861 ttggaaacaa aaaggaacag gtagagcaag acaaggttct acaagatctg tacaatgggt
     1921 aggtggagga gttgcttttg cacctaaacc aagaagctac aaatatacat tacctaagaa
     1981 ggtaagaaga ttagctatga agagtgcttt atcttcaaaa gttcaaaata gtgaagttat
     2041 agtattagat gcattaaaca tggatgctcc taagactaaa gaatttgctc aaatattaaa
     2101 caatataaat gctgctaaaa aagctttagt agttatagct gacaaaaacg ataacgtaat
     2161 aaaatcagct agaaatatag aaggtgttca aactgcatta gttaatacta tgaatgtata
     2221 tgatatatta aaatacgatt catttataat aactacagat gctgttaaaa aagtggagga
     2281 ggtgtacgca taatgactaa tccacatgat gtaataataa gaccagttgt aactgagcac
     2341 agtatggctg aaatgggtga aaaaaaatac acttttgttg tggctaaaga tgcgaacaaa
     2401 actgaaataa aaaaagcagt agaaaaagta ttcggagtta gtgttgataa agtaaatact
     2461 ttaaactacg atggaaaagt taaaagaatg ggtagaactc aaggaagaac atcaagcttt
     2521 aagaaagcag tagttaaatt aactgctgat agtaaagaaa tagaattctt ccaaggaatg
     2581 tagtattata acaaacgaag gagggaaaac agatggctat aaaaaagttt agaccaactt
     2641 ctcctgcctt aagacaaatg acagttttag tttctgatga aataacatgt aatcaaccag
     2701 aaaaatctct tttagttaac ttaaagaaaa atgctggtag aaacgtacat ggtagaataa
     2761 ctgttcgtca tagaggtgga ggacaaaaaa gaaaatatag aataatagat tttaaaagag
     2821 ataaagatgg tatacctgct aaggttgcta ctatagaata tgatccaaac agaactgcaa
     2881 atatcgcatt attaaactat gctgatggag aaaaaagata tatattagct ccagttggaa
     2941 ttaatgttgg agatactata ttatcaggat taggtgctga tataaaacca ggaaactgtt
     3001 tagcattaaa agatatgcca gttggtacta tcattcataa tatagaatta aagccaggaa
     3061 aaggagctca attagttaga tctgctggag tttctgcaca attaatggct aaagaaggaa
     3121 aaaatgcttt attaagatta ccatcaggtg agatgagatt agtaagcata aactgtaaag
     3181 ctactatagg tcaagttgga aatatagagc atggtaacgt agttatcggt aaagcaggta
     3241 gaaaaagaca tatgggaata agacctactg taagaggttc tgtaatgaac cctaatgacc
     3301 atccacacgg tggaggggaa ggtagatctc caataggtag accatctcct gttactccat
     3361 ggggtaaacc agctcttgga tacaaaacta gaaagaaaaa taaagcttca aataaactaa
     3421 tagtatcaag aagaactaag tagtaaattt atttttgctc ggaaaggagg aatataaatg
     3481 tcaagatcaa ctaaaaaagg gccttttgtc catgcaagac ttttaaagaa gatagaagct
     3541 atgaatgcta gtggaaataa agaagttata aaaacttggt caagatcttc aactgtattt
     3601 ccacaaatgg tagaaaacac tatagctgtt catgatggaa gaaaacatgt tccagtatat
     3661 ataacagaag atatggttgg acataaatta ggtgagttcg ttcctactag aactttcaaa
     3721 ggacataagg atgacgaaaa atctaataag agaaaataat taaattatga ctaagaaagg
     3781 aggaataaca atggaagcaa aagctactgc taaatacgta cgtgtatcac caagaaaagc
     3841 aggccaaata tgtgaccttg ttagaggaaa gaatgttgat gaagcattag caatattaaa
     3901 gtttactcca agaggagcag cttcaataat agctaaggtt gtaaaatcag ctaaagctaa
     3961 cgcagaaaac aatcacgaaa tggatactga aaaattatat atagcatcaa tagttgctaa
     4021 tcaaggacca acaatgaaga gattcatgcc tagagctatg ggtcgtgcaa ctacaataag
     4081 aaaaagaact tctcatatag aggttgttgt taaagaaaaa aaataattaa tagataggag
     4141 ggaaagtaat gggtcaaaag gttaatccac acggcttaag ggtcggtgtt ataaaagatt
     4201 gggactcaag atggttcgct actgataaaa aagagttcgg aaacttatta ttagaagacc
     4261 ataatatacg taaattctta aagaaaagat tatactcagc tggagttgct aagatagaaa
     4321 tagaaagatc agctaacaaa ataaaaatgg acttacacgt tgctaagcct ggtgtagtta
     4381 taggaagagc tggtgcagga atcgaagcat taaaagctga attagaaaaa atgacaaaga
     4441 aaactataat agttaatata gtagaagtaa gaagtacaga taaaaatgct caattagtag
     4501 ctgaaaatat agctttagct atagagagaa gggttgcttt cagaagagca atgaaacaag
     4561 ctatacaaag agcaatgaaa tctggtgcta aagggataaa agtttctgct tcaggaagat
     4621 taggtggagc tgaaatggct agaactgaag gttatagtga aggaaatgtg ccactacaaa
     4681 ctttaagagc agatatagat tatggtttcg ctgaagctga tacaacttat ggaaaaatcg
     4741 gtataaaagt ttggatatgt aatggtgaag ttttaccaac tagagacggt gtaaatccaa
     4801 gagaagaaag cagaaagagc gatagaagag acaacaagag agataataga agaaacgata
     4861 gaagaggaaa tgacagaaga ggaaatgata acagaggaaa ctacagagga caaagacctc
     4921 aaggtggatc aagacctcaa agaactgaaa acaaaggaaa ttaataatag ttaggttcaa
     4981 ggaaggagga aaaatactca tgttaatgcc aaaaagagta aagcgtcgta gagttcatag
     5041 aggaagcatg gctgggcaag ctcataaggg taataaagtt acttatggtg agtttggatt
     5101 agtagcatta gaagcttctt ggataacttc taatcaaata gaagctgcca gaatcgcgat
     5161 gactagatat ataaaaagag ggggaaaggt ttggataaaa atattccctc ataaaccagt
     5221 aacaagaaaa ccagcagaga ctcgtatggg tgcagggaaa ggttctccag aatattgggt
     5281 agctgtagtt aagccaggaa gagttatgtt tgaattagca ggtgtttctg aagataaagc
     5341 aagagaagct atgagacttg ctgcacataa attaccaatc aaatgtaaat ttgttaaaaa
     5401 agaagattta gaagtaaagg gtggtgaata ggatgaaagc taaagaatta agagatttaa
     5461 caagcgaaga gctaatgaac aaattaaacg acttcaaaag tgaattattt agcttaagat
     5521 tccaattagc tactggtcaa ttagaaaata cagctagaat aaagtttgtt aagaaggata
     5581 tagcaaaagt taaaactgtt cttgctgaaa gaaagttata cgaaactaga gcttaatttg
     5641 gaaaggaggc tttttaaaca tggaaagagg aagaagaaaa gttagaatag gccgtgttgt
     5701 tagtgataag atggataaaa caatagtagt agctgttgaa gaattcgtac gtcatccact
     5761 atataataaa cgtgttaaga gaactaagaa attcaaggct catgatgaaa agaatatatg
     5821 taacatcgga gatagagtta aaataatgga aactagacca ttatctaaag ataagagatt
     5881 cagactagtt gaagttgttg agaaagttaa gtagtttttg aagaaggagg gattacgata
     5941 tgatacaaca agaatcacgt ctaagagttg ctgataactc aggagctaaa gaacttttat
     6001 gtatacgtgt tctaggcgga agtaaaagaa gatatggtaa cataggcgac gttatagttg
     6061 ctactgttaa aagtgcaaca cctggtggag ttgtaaaaaa aggtaaggtt gttaaagctg
     6121 ttatagtaag aagcaaacaa ggcgtaagac gtaatgacgg aagctatata tcttttgatg
     6181 aaaatgctgc tgttataata aaggacgata aaactccagt aggaactcgt atattcgggc
     6241 ctgttgctag agagttaaga gacaatgaat tcatgaaaat agtttctctt gctccagaag
     6301 tactataatt aaggaggtgc aataggacat gatgcgtgtt aaaaaaggtg acactgttgt
     6361 agttatagca ggtaaagata aaggtaaaaa aggttcagtt ttaaaggtat atcctaaaac
     6421 tagcaaagtg ttagttgaag gtgtaaatgt aataactaaa catcaaaaac caagtgctat
     6481 gaaccaacaa ggtggaataa taaataaaga agccccaata cacatatcta atgtaatgcc
     6541 atttgatcct gaaacaggaa aaggcgttag agtaagatat gaagtaaaag atgggaacaa
     6601 agtaagagta tcagcaaaga gcggaaaaga attataataa atattgcttg aaaggaggga
     6661 ccttaaatgg cttctagatt acaagaaaaa tacatgaaag aagttgctcc tgctttaatg
     6721 gagaaatttg gatacaaaaa cgtaatggag atacctaagt taaataaaat agttattaac
     6781 atgggtatag gtgacgctag agaaaatcca aaaggattag aaaaaggcgt tgaagaatta
     6841 gaaatgatat caggacaaaa gcctgttata actaaagcta gaaaatctgt tgctaacttc
     6901 aaattaagag aaggaatgcc aataggaaca aaagttacat taagagctga caaaatgttc
     6961 tacttcatgg acaaattagt ttcagtttct ttaccaagag ttagagactt tagaggagtt
     7021 aaccctaatg cttttgatgg tagaggaaat tatgctttag gagttaaaga acaattaata
     7081 ttccctgaaa tagaatatga taaaatagat aaagtaagag gaatggatat aatatttgtt
     7141 actacagcaa aaactgacga agaagctcgt gaattattaa aattattagg aatgccattt
     7201 tctaagtaag caaaggaggg attcccgtgg ctagaaaagc gatggttgtt aagcaacaaa
     7261 gaaagcaaaa gtacgctact agagaataca ctagatgtac tatatgcgga agaccgcatt
     7321 cagttttgaa aaaatttggt atatgccgta tatgctttag agaattagct tataaaggtc
     7381 aaatacctgg tgttagaaaa gcaagctggt agaagcttga ttagaatgga aggagggcaa
     7441 caaaatgaca atgacagatc caattgcaga tatgcttact cgtataagaa atgctaatgt
     7501 tgttaagcat gaaactgtag atgttccagc ttctaatatg aagaaagaat tagctagaat
     7561 cttattagaa gaaggtttca taagaggtta tgatgttata gaagatggaa aacaaggtat
     7621 cataagaata caattaaagt acggacaaga aggcgaaaga gttataacag gtcttaagaa
     7681 aatatctaag cctggaatga gagtttacgc tgctaaccat gagataccaa aagtattaaa
     7741 cggattagga atatcagtta tatctacttc aaaaggaata ttaactgaca agcaagctag
     7801 aaaagaaaat gttggtggag aagtaatctg ctacgtttgg taattaatat gaacaatgta
     7861 aggaggtgcg accatgtcaa gaataggtgt taagccaata ataataccag caggtgttga
     7921 agttactata gctgaaggaa atttagttac agtaaaaggt ccaaaaggaa ctttaactaa
     7981 acaattaagt gctgagttaa acataaaaaa agaagaaaat acaataatgg ttgaaagacc
     8041 aactgataat aaaaaacata gatctttaca cggactaact agaactttat tagataatat
     8101 ggttgtaggt gtaaatactg gtttcgaaaa gaaattagaa ttaaaaggtg ttggatatag
     8161 agctcaaaaa caaggaaaga aattagttat gaacttaggt ttctctcatc cagttgagat
     8221 ggaagatcca gaaggaataa ctgttgaagc tccaaaccaa acagagttaa tagtaaaagg
     8281 tatagacaag caattagtag ggaattatgc tgctaagata agagcttgga gaaagccaga
     8341 gccatacaaa ggtaaaggta taaaatacgt tgatgaagta atcagacgta aagaaggaaa
     8401 aactggtaaa aaataatacc aaaacttaaa cgctagaaag gagtgagcta ggtgttaaaa
     8461 aaggctgata aaaatgctaa tagacttcaa agacataaga gagttcgtag aaaaataagc
     8521 ggtacttctc aaagaccaag attatgtgta tttagaagtg ctaacaatat atatgctcaa
     8581 ataatagatg acacaaaaag agtaactcta gttgctgcat cttctttaga agcagaagtt
     8641 aagagtgctg tcaatcatac aggaaacaag gaagcagcta agaaagttgg agaattagtt
     8701 gctaaaaaag ctgttgaaaa aggaatcact gaagttgtat ttgacagagg tggatactta
     8761 tatcatggaa gaattcaaga attagctgaa ggtgctagag aagctggtct taagttctaa
     8821 tacgaaggag ggaaaaatac atgctacgtc gtaagccgat agatgcagga caacttgact
     8881 tacaagaaaa agttgttgaa gtaagacgtg ttactaaggt tgtaaaaggt ggtagaaatt
     8941 tcagatttgc agcattagta gttgttggag atgaaaacgg acacgttggt ataggtgctg
     9001 ggaaagcaat ggaagtacca gacgctataa aaaaagcagt tgaagatgct aagaaaaatc
     9061 taatagtagt gccaatagtt gggactacaa ttcctcacga agtacgcgga cactttggtg
     9121 ctggaaatat attaataatg cctgctgtag aaggtacagg agtaatagct gggggacctg
     9181 ctagagccgt acttgagcta gctggactaa aagacgttag agctaaatct ttagggtcta
     9241 acaatccaag aaatatggta aatgctacaa tagaaggact taattctcta aaaacagttg
     9301 aagatatagc taaacttaga ggtaaaaaag ttgaagaact tctagggtaa ggaggtagtg
     9361 taaaatggct aaattacaaa taaagttagt tagaagtgtt ataggaacta ctcctaacca
     9421 aaaaaagaat gttgaagcgt taggattaag aaaaagagaa caagttgttg taaaagaaga
     9481 caatgctcaa acaagaggta tgataaataa agtaagtcac ttattagaag taactgaaat
     9541 agctgaataa tttttataaa gtagtgcaag gaggtgcaat ccatgaagtt acatgagtta
     9601 aaacctgctg aaggtgcagt aagagctaag agaagattag gtagaggtac tgcaactgga
     9661 caaggtaaaa ctgcaggacg tggacaaaaa ggtcaatggt ctcgttctgg tggtggagta
     9721 agagtaggat ttgaaggtgg acaaatgcca ctagctagaa gacttcctaa gagaggtttc
     9781 aataacatat ttaagaaagt ttacacagaa gttaatgttg aagttttaaa cagatttgaa
     9841 aatggaacag aaataactgc agaattatta aaatctacta aaactataag caaaataggt
     9901 aaagacggaa ttaaaatctt aggtgaaggt aatttagaga aagctttaac tgttaaagct
     9961 gctaaattta cagcttcagc tcaagaaaaa atagaaaaag ctggtggaaa agcagagtta
    10021 gtataataac ctgctaatct cctagccagt acaggcgggg tgaattagcg tgctgtcaaa
    10081 attaaaacaa gcttggaaga ttaaagcagt aagaaaaaaa gtaatgtata cacttatgat
    10141 gatcgtgata ttcagaatag gtactactat accagttcca ggcatagaca ctagtattat
    10201 acaaaagatg gtaggcggca atagtctact ttctctgtat aatatgttta ctggtggagc
    10261 atttagtaac ttttcactat ttgctttagg tataagtcca tatatcactg catcaatcat
    10321 aatacaactt ctaacagtag gttttgaaag tttagcagaa cttcaaaaat ctggtgaaga
    10381 aggaaagaaa aaaatcaata agtacactaa atatacagca ctagctctag cagttgtaca
    10441 agctttggga attacattag gaattgtaag aagtgcttta atatcaaata gtgtgttttt
    10501 tatcacaact gttgtaataa cattagtttc agcaagtatg ttagtaatgt ggattgggga
    10561 caaaattact gaaaaaggaa tcggtaatgg tagttcagta ataatatttg caggtataat
    10621 atcaagaata cctacagatg ttattaaaat atcgcaacaa gttaaatctg gcgaagttgc
    10681 accttgggtt atagtgattc tagctgtagt tatattactt acagtaacag gagttacatt
    10741 tatacaagaa gcaactagaa agatacctgt acaatatgct aaaagagttg ttggaagaaa
    10801 aatgtatgga ggacaaagtt ctcatatacc aatgaaagtt aaccagtcag gagttatgcc
    10861 tataattttt gctagttcac ttttagcttt ccctcaaaca atagctatgt ttatgggtcc
    10921 aaatgctcag gcttttgttc aaaaatactt aagtatggca acagaacaag gattttggac
    10981 atatagatca attgagattc tacttataat tttcttctca tatttttata caactgtatc
    11041 atttaataca gaagacatat ctaaaaatat gaaaaataat ggtggattta taccaggtat
    11101 aagaccaggt gagcctacta tggattattt aaatagaatt ttaactagat taactttagc
    11161 tggagctact ttcttagcaa taattgctat ggtgccagct cttacaacac attatatgaa
    11221 agtaaatatg agtctagctg ggacttcatt gctaatcgtt gttggagttg ctttggagct
    11281 taagagacag ttagagtcaa acttagttat gagaagctat caaggtttct taaaataaaa
    11341 tggagatgga taatatgaga ataatattac ttggacctcc aggtgctggt aaaggtactc
    11401 aggcggcagg aatagtagaa aaatacaata tacctcatat atcaacagga gatatattca
    11461 gaaagaatat aaaagaggga acagaacttg gaaaaaaagc taaagaatac atggaccaag
    11521 gtttattagt accagatgag ttaactgtag gtttagttac tgatagaata tctcaagaag
    11581 attgtaaaaa tggatttatg ttagatggat ttccaagaaa tgtagcacaa ggagaacatt
    11641 tagatatctt cttaaaaaat gctggtatat cactagataa agttgtcaat attgaagttg
    11701 ataagagtat attagtgtct agagcagttg gtagaagaat atgtaagtct tgtggagcta
    11761 cttaccatgt tgagtttaat cctcctaaag tagaaggtgt atgtgatgta tgccaaggag
    11821 aattatatca aagagctgat gataatgaag aaactgtatc taagagaata caagtttatt
    11881 tagatgaaac taagccttta gtagattatt atagcaaaca aggtataata gcagatataa
    11941 aaggtgatca agcaatagat aaagtatttg aagatattgt cgcagcctta ggaagtggaa
    12001 aataaatgat tatcttgaaa tcaaaaaaag aaatagaact tttaagagaa gcaggtaaaa
    12061 tagttgctga cactcatgaa gttttaagaa aagctatttc tccgggaata tctactttag
    12121 aattagataa aatagctgaa gagaatataa gaaaatacaa tgcagaacct tcttttaaag
    12181 gatatggagg ttttccagga agtatatgtg cttctatcaa tagagaggta gtacatggta
    12241 ttccaggaga aactatatta caagaaggtg acattgtaag tttggatata ggagcctatt
    12301 ataaaggata tcatggtgat tctgcgaaaa ctcacggagt aggcatgata tctgaagaag
    12361 ataggaaatt gatagaagta actagagaaa gcttctatga aggaataaaa tttgctaaat
    12421 taggatatag actttcagat atctcacacg cagtacaaac acacgttgag aaacatggtt
    12481 tctcggtagt tagagattta gtgggtcatg gagttggagc aaatcttcat gaagacccac
    12541 aagtacctaa ttatggactc ccaggaaaag gaccaagact tagagaagga atggttattg
    12601 ctatagagcc aatggttaat gcaggtcgtt atcatgtaaa gactctatca gatgggtgga
    12661 cgactgttac aatagatgga aaaaaatcag ctcattatga gcatacgata gcaattactg
    12721 aacatgaacc tttgatattg acaaagttgt aatttaaaaa gtaggtgaaa aaagtgctat
    12781 cagataattt aagtataggt caagttgtta aagtttcatt aggacgagat aaaggaaatt
    12841 tattctttgt agtcaaaata attaataatg aatatgtatt aatagctgat ggaaaaaaga
    12901 gaaaacttga caaacctaag ttaaagaaag tgaagcactt aaaaaaatat aattttatta
    12961 atgatgaagt tagaaaaaga gtagtatctg gacaagagat tacagattct tttttaagag
    13021 ctgaacttac taagttaaat tagataattt aacttattga aatggagggc tggttagtta
    13081 atggccaaaa aagatgttat agaattagaa ggtacagttt cagaagcttt acctaatgct
    13141 atgttcaaag ttaaactaga aaatggacat gagatattat gccacatttc tggaaagcta
    13201 agaatgaact tcataagaat tcttgaaggt gacaaggtga atgttgaact ttctccatat
    13261 gaccttacaa gaggaagaat tacttggcgt aagaagtaga ctatattaat atttagtcta
    13321 aggagggatt aataatgaag gttagaccat cagtaaaacc aatatgtgaa aaatgtaaag
    13381 taataaaaag aaaaggaaaa gtaatggtta tctgtgaaaa tccaaagcat aagcaaaagc
    13441 aaggataaga aattattact agcattttgt taaattttat agtataatac tatattgtga
    13501 tgttaacaaa agaacgttaa aatcgttgaa caatctggcg taggattggc atatgatgtg
    13561 aagttttaaa cactaaaaac tatgtgtagg aggtgcgatc atggcaagaa tagctggggt
    13621 agatttacct agagaaaaaa gagcggagat aggcttaact tatatatatg gtataggtaa
    13681 agcaactgct aacgaaatat tagctaaggc tgagataaat ccagatacta gaataaaaga
    13741 tttatcagaa gatcaagtta atgagttaag aaaagttata gatgacgatt tcttagttga
    13801 aggtgactta agaagagaaa ttgctttaaa cataaagaga ttaagagata taaaatgtta
    13861 tagaggaata agacacgcta aaggtcttcc attaagagga caaagaacta agactaatgc
    13921 tagaactaga aaaggtccta gaaaaacagt atctcgtaaa aagaaaaaat aaataaataa
    13981 taactagatg aaggagggaa aaggaaaatg gctaaaccaa aaaagaaagt tacacgtatt
    14041 agaagaagag aacgtaaaaa tatagaacgt ggtcatgctc atatacaatc aactttcaat
    14101 aatacaataa taactttaac tgacgttcac ggaaatgcta tatcttgggc aagttctgga
    14161 caattaggat tcaaaggatc aagaaaatca actccatttg catctcaaat ggctgctgaa
    14221 acagctgcaa aagctgcgat ggaacacgga ctaaaaagtg ttgaggtatt cgtaaagggg
    14281 ccaggttcag gaagagaagc tgcaataaga gctttacaag caactggact agaagtaact
    14341 atgataaaag acgttactcc aatcccacat aacggatgca gaccaccaaa gagaagaaga
    14401 gtgtaattaa taagagtaca ataggaggtg tagataaatg gcaagatata caggtgcatc
    14461 atgtagacaa tgccgtagag agggaatgaa attattcctt aaaggtgata gatgttatac
    14521 agacaaatgt gctatagtaa aaagaaacta tgctccaggt caacatggcc aaggaagaaa
    14581 gaaagtttct aactatggat tacaattaag agaaaaacaa aaagttaaaa gaatatatgg
    14641 agttttagag actcaattta gaaatttata tgaacgtgct gaaaatatgc ctggtaaagc
    14701 aggtgagaac ttattaagtt tattagagag aagattagat aatgtagttt acagaatggg
    14761 actagcatct tctagaaaag aagctagaca attagtgact catggtcatt tcactttaaa
    14821 tggaaataaa gtagacatac cttcattaat agttaaggtt ggagatgtta tagaagttaa
    14881 agagaaatca agatcttctg caaaattcaa aaatttagta gaagttaact caagaatagc
    14941 tcctaagtgg ttagaagcta atgtagaagg aatgacagca aaagtagttg gtgttccaac
    15001 aagagaagat atagatcttg agatagcaga gcacttaatc atagaacttt actctaaata
    15061 ataagcacac ttttaaaaat tattttaaaa ttttgtttac cctcagtgga ttactgaatt
    15121 ttaaggaggg ttttgtccat gatagaaata gaaaagccaa aagtagatat agttgagctt
    15181 agcgaagact atagatatgg taagtttgtt atagagcctc tagaaagagg atatggaata
    15241 actataggta acgcattaag aagaatatta ttatcatcat taccaggtgt agcagtgaat
    15301 gctataaaaa tagatggagt tcttcatgaa ttttcaacaa tacctggtgt taaagaagat
    15361 gttactgaga taatattaac tttaaaagag ctttcagcaa ctatagatgg tgaaggaagt
    15421 agaacactta aaatagaagc tcaaggacca tgctctatca caggtgcaga tataatctgt
    15481 cctccagatg ttgaaatatt aagtaaagat ttagcaatag ctacattaga tgataatgct
    15541 aaacttaata tggagatatt tgtagataaa ggtagaggtt atgtttctgc tgaagaaaat
    15601 aaaacagaga atgttccaat aggtgtttta cctgtggatt caatatatac tcctgttgag
    15661 aaggttagtt atcatgtgga aaacacaaga gttggtcaaa aaacagatta tgataaatta
    15721 gtactagaag tttggactaa tggtagtata aatcctcaag agggaatatc attagctgca
    15781 aaggtattag ttgagcattt aaacttattt atagacttaa ctgaacatgt aagtagtgtt
    15841 gaaatcatgg tagaaaaaga agaagatcaa aaagaaaaag ttcttgaaat gactatagaa
    15901 gaattagatt tatcagttag atcatataac tgtttaaaga gagcgggaat taatacagtt
    15961 gaagaattag ctaataaatc tgaggatgat atgatgaagg ttagaaacct aggtaagaag
    16021 tcattagaag aggtaataca aaaactagaa gaacttggat tgggattaaa accaagtgaa
    16081 gaatagcgag caaaggaggg ataagaatgg ctaagtaccg taaattagga cgtgaaacag
    16141 ctcacagaaa ccttatgtta agaaacttag taacttgctt actaagaagt ggaagaatag
    16201 aaactacagt gactagagcg aaagaaactc gtagaatggc tgaaaagatg ataactcttg
    16261 ctaagagagg agatcttcat gctagaagac aagttttagc ttatgttatg gatgaaacag
    16321 tagttaataa cttattcaca gatttagctc caaaatatgc tgagagaaat ggtggataca
    16381 ctagaataat aaaaataggg ccaagaaaag gcgatgctgc tgaaatggct tttatagaat
    16441 tagtatagta aggaaaggat taggcttgat ggcttaatct tttttttatt tttttgacta
    16501 aggtatgata taataatgtg taaaatgatt tttataagtt attgcttact aaaaggagta
    16561 tgagttaatg gataatatag taaaggtaaa taatatttcg tttgagtata ttacagatga
    16621 agcaaaactt aaagcaatag ataatttaag cctagatgtt aaaaaaggag aatttgttgc
    16681 gataatagga cataatggtt ctggtaagtc tactttatct aaaaacttaa atgctattct
    16741 tatgcctact gaaggaaata ttcttattga tgatatggat actaaagaag aagaaagatt
    16801 atgggatata agacaaactg caggcatggt atttcaaaat ccagataatc aaatagttgc
    16861 tactatagta gaagaagatg ttgcatttgg acctgagaac ttaggtatag aaccaaaaga
    16921 aataagacga attgtagagg agtctttaaa aagtgtaggt atgtatgatt taagagatag
    16981 acagcctcat ttgttatcag gaggtcaaaa gcaaagagtt gcaatagcag gaattattgc
    17041 tatgaggcct aaatgtataa tatttgatga agcaacagca atgttagatc catctggaag
    17101 aaaagaagtt atgaaaacaa taaaaagact taataaggaa gaaaatataa ctgttataca
    17161 tataacgcac tttatggaag aagcagtaga agctgataga gttgtagtta tggaaaaagg
    17221 aaagaaaatc ttagagggaa ctcctagaga agtattcagt aaaataaaga tgttaaagga
    17281 aatcggttta gatgtacctt gtatgacaga gttatctagt ttattaatag aagaaggtat
    17341 aaatattagt agtgatatat taactgtgga tgagatggtg atggaattat gtcaattata
    17401 gtaaagaatt taacacatat atataatgaa gggatgcctt ttgcaagtaa ggcacttgat
    17461 gatgtttctt ttgagattaa agatagagat tttgttggtc ttataggtca tacaggctca
    17521 ggaaaatcta cattaataca acatttaaat ggattactaa agccttcctc aggagaaata
    17581 tttataaatg attttaatat aacagataaa aacttgaatt taactgagat tagaaaaaga
    17641 gtaggggttg tatttcaata tccagaatac caattgtttg aagaaacgat tgataaagat
    17701 atagcttttg gaccctctaa tttaggctta gaggagtctg agatacataa cagggtaaaa
    17761 gcatcaatgg aagctgtagg acttgattat gagggattta aagacaaatc tccttttgaa
    17821 ttatctgggg gacaaaagcg tagagtagca attgctggag ttatagccat gaacccagaa
    17881 gttctcatat tggatgaacc aactgctggt cttgaccctg gtggaagaga tgaaattttt
    17941 aacttaataa aagacttaca tgaaaaaaag aatatgacta taatactatc atcacatagt
    18001 atggatgata tggcaaagtt agcaaaaact ttaattgtta tgaatcatgg tagcgtagaa
    18061 tttatgggaa ctcctagaga agtatttaaa tcaaatgcta gtaaattaaa agatatagga
    18121 ttagatattc cacaagtttt agagcttgca ttgaaattga gagaaaaagg ctttgacatc
    18181 agtgaggata tattgacttt agaagaagca aaacaggaaa tattaaaagt tgtgagagga
    18241 cgaggattat gttaaaagat ataactatag ggcaatacta cccaacaagt tctgctattc
    18301 ataaattaga tccaaggata aagcttgtag cgacaattgt atttatggta tctatatttg
    18361 tagtaaataa attttggcct tatatagtag ttttattatg tttattagct atgataaaat
    18421 tggctaatat accagtcaaa tatattgtta agggtgttaa acctcttaaa tggattattt
    18481 tgtttacatt tcttataaat atttttttct taccaggtga tgaaatatgg tcatttggat
    18541 ttttagctat tacaaaacag ggtctaagac aagcaatttt tatggcaata agattaatat
    18601 ttttagtagt tggtacatca ttgcttactt taacaacttc accaatagaa ttaactgatg
    18661 gaatagagag attgttgaat ccatttaaga aaattggttt gccagttcat gaacttgcaa
    18721 tgatgatgac aattgcttta cgttttattc ctacattgtt agatgagaca gacaaaataa
    18781 tgaaggctca gatgtctaga ggtgcagatt ttgaaagtaa gaatcttata aatagagcaa
    18841 agaatttagt accacttttg gtacctttat ttgtaagtgc atttagaaga gctgatgaat
    18901 tggctatggc catggaggcc agatgttaca gaggtggaca taataggact aagatgagag
    18961 agtctgttat atcaagaagg gattatatgg catgtgtatt tcaggttgtt tatctgggag
    19021 caattatagc tactagattt atagcaattt aattaataag ttatagatat aatgaggtaa
    19081 agtatgagaa atataaaaat taaaatacaa tacaatggta agaattattg tggatggcaa
    19141 aagcaacctg attctttagg gatacaaggt acaattgaaa gggctatata tgatataaca
    19201 aaagaagaaa ccagtcttat agggtctggt agaactgatt caggagttca tgctattggt
    19261 cagattgcaa attttaaaat taattcaggt ataagtatag aaagtatacc aatggcacta
    19321 aatgccaagt tgccaaaaga catatcagtt atagaagcat gtgaagtaaa tgatgatttt
    19381 cactccagat acagtgcaaa aggtaaaaca tataaatatt tagtatataa tagcaagttt
    19441 agaaatccaa tacttagtga gatatcatat caagtaaaat atgaacttga ttttgataaa
    19501 atgtgttcag aagcaaaaag tttattagga acacatgatt ttaaaggttt tatgagttct
    19561 ggttcatctg taaaagatac agttagaacg atatatgata ttgatataag taaaaaagat
    19621 gacttgatta cttttgagat tagtggtaat ggttttttat ataacatggt gaggattatt
    19681 gttggaacac ttgttgatat gggtcgtggc agaattaacg aaccattttt agatataata
    19741 caatcaaaaa ctaggtcaag atgtggacat acagctccag cacaaggatt atttctcaaa
    19801 aaagttcatt attaacttga cacaccaggc tacatgtatt aaaatatatg agaatgtgtt
    19861 aataagtcca cttgccccgg acttgacata aacggtaaaa aaattttatg aaaagtagtt
    19921 aaggagggac agttatgaaa agttatatag ctaagccaac tgatgtacaa agaaaatggt
    19981 acttagttga tgctgaagga aaaacattag gtcgtttagc aacagaaatt gcgacagtat
    20041 tgagaggtaa acataaacca acatttactc ctcacgttga tggtggagat tttgttgttg
    20101 tagtaaatgc agaaaaaata gttttaagtg gtaagaaatt agatcaaaaa tattacagat
    20161 accatactgg ttatgtaggt ggattaaaag aaatatctta cagagatatg atggataaga
    20221 aaccagaaga agttatatca catgctgtaa gcggtatgtt acctaaaaat aaattaagaa
    20281 gcagaatgat gactagatta agagtatttg caggtgctga gcacactcat gcagctcaaa
    20341 atccagaagt tttaaacttt aaataagatt aataggtgaa aggaggagtt tataatggct
    20401 aacgttcaat attatggaac tggaagaaga aaaagttctg ttgctagagt aagactagtt
    20461 gcaggtgaag gaaatatatt agtaaatgga agagcattag aaaattattt taattatgag
    20521 acattaataa gagatgttaa acaaccatta gttttaactg gtaatgaaaa taaatatgat
    20581 gttatagtaa aagttgaagg tggaggattc actggacaag ctggagctat aagacatgga
    20641 atatctagag ctttattaaa agctgattta gatttaagac ctgctttaaa gaaagaaggt
    20701 ttcttaacta gagatgcaag aatgaaggaa agaaagaaat acggattaaa agcagcaaga
    20761 agagctccac aattctcaaa aagataatta cttatttttt tggaaaagca aaatccttta
    20821 tttactgtta ttcagaaagt attggtattt taaaaatgtt gggttaagtt aattattgat
    20881 atataataaa ataataagat atcttattag gatgtttttc attaagaaga acatcctttt
    20941 tattttgact atttaataaa aaacatatgc taataacatt taaattttat ttttataata
    21001 ttgtaattta aaagtttata taaggttata tattttaaga tattatttaa caatataaat
    21061 tctgaatata cgttatcaaa atttataata taaactaagt ataatttatt gtatagtatt
    21121 gaatgttaga taaacatagt gaattaaata gggacagaaa tataatatca ttacataata
    21181 atatattaat accaataaat aaagatatat caatattaaa aaaatttaaa tgtttgtact
    21241 aatatatgga atattatagt gtttttataa gtatacatat acagggtgat gttgtgagaa
    21301 agtacataaa acatataatt tttagttttg caatgatatg tctagtagta gtatccatat
    21361 ttgaaattaa aaatatttct gaagatgtta tcaagtatat gccagtaaca aacaaaacta
    21421 taattttaga tgctggtcat ggaggcattg atccaggtgc attaaataag gataagagta
    21481 catctgaaaa ggatattaac ctagcaataa cacttaagct tagagagctt atagaatcaa
    21541 gtggtggcct tgtaatatta actcgagaag atgacagtag cctttataaa gaagaaaata
    21601 ataaaactac aagacaaaaa tataatgaga atttgaaaaa tagaaaagaa ataatatcta
    21661 attctaatgc caatatgttt gtctctatac atcttaatgc atttgaacaa tcaaaatact
    21721 atggagctca aactttttat cctaaagaca aacaagacag taaagaatta tcgaagtgta
    21781 ttcaagaaga acttaaaaga gtagtagata agacaaacaa cagagaagtc aaaccaaggg
    21841 atgatatata tcttttgaaa gaaaataata ttccatcagt actgatagaa tgtggttttt
    21901 tatcaaatga aaaagagtgt aaactcttaa ctgatgaaac atatcaagaa aaaatagcat
    21961 gggcaatcta cataggaata caaaaatatt taagttgaaa taactataaa aataggtcta
    22021 aatatgtaaa tagcttgtat taaagcagtt aaaatgcatt aatataggct atttttattt
    22081 tgacaaaaaa atatttaaaa taaaagttaa aaagttgttg acttagaata atatagatga
    22141 tattatatat gagtgcccaa aaggagcacc aaaataagac
//
LOCUS       DAEPUT010000067        22140 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.069, whole genome shotgun sequence.
ACCESSION   DAEPUT010000067 DAEPUT010000000
VERSION     DAEPUT010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22140
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.069"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            2..745
                     /locus_tag="KRL22_002737"
     CDS             2..745
                     /locus_tag="KRL22_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273209.1"
                     /translation="MLKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSGAGK
                     TTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMKLMD
                     NIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLITNP
                     TVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNELYMINDGN
                     IKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            746..2653
                     /locus_tag="KRL22_002738"
     CDS             746..2653
                     /locus_tag="KRL22_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1273210.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQDENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNVYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            2805..3485
                     /locus_tag="KRL22_002739"
     CDS             2805..3485
                     /locus_tag="KRL22_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1273211.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            3479..4498
                     /locus_tag="KRL22_002740"
                     /pseudo
     CDS             3479..4498
                     /locus_tag="KRL22_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
     gene            4929..6089
                     /locus_tag="KRL22_002741"
     CDS             4929..6089
                     /locus_tag="KRL22_002741"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBH1273212.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLIQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            6091..6498
                     /locus_tag="KRL22_002742"
     CDS             6091..6498
                     /locus_tag="KRL22_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273213.1"
                     /translation="MSNNKKKKRKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNI
                     PTISFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVET
                     KRGFSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            6760..7068
                     /locus_tag="KRL22_002743"
     CDS             6760..7068
                     /locus_tag="KRL22_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1273214.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            7157..8503
                     /locus_tag="KRL22_002744"
     CDS             7157..8503
                     /locus_tag="KRL22_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1273215.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            8736..9833
                     /locus_tag="KRL22_002745"
     CDS             8736..9833
                     /locus_tag="KRL22_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH1273216.1"
                     /translation="MGSLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKTKADGIRLDIGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLTGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWTVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            9932..10846
                     /gene="murQ"
                     /locus_tag="KRL22_002746"
     CDS             9932..10846
                     /gene="murQ"
                     /locus_tag="KRL22_002746"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBH1273217.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            10956..11875
                     /locus_tag="KRL22_002747"
                     /pseudo
     CDS             10956..11875
                     /locus_tag="KRL22_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
     gene            11892..12743
                     /locus_tag="KRL22_002748"
     CDS             11892..12743
                     /locus_tag="KRL22_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1273218.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            13355..14416
                     /locus_tag="KRL22_002749"
     CDS             13355..14416
                     /locus_tag="KRL22_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH1273219.1"
                     /translation="MKKIRKLTTKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(14532..15506)
                     /locus_tag="KRL22_002750"
     CDS             complement(14532..15506)
                     /locus_tag="KRL22_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273220.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            15962..16843
                     /locus_tag="KRL22_002751"
     CDS             15962..16843
                     /locus_tag="KRL22_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HBH1273221.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            17225..18028
                     /locus_tag="KRL22_002752"
     CDS             17225..18028
                     /locus_tag="KRL22_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273222.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            18040..19170
                     /locus_tag="KRL22_002753"
     CDS             18040..19170
                     /locus_tag="KRL22_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1273223.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            19174..20583
                     /locus_tag="KRL22_002754"
     CDS             19174..20583
                     /locus_tag="KRL22_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273224.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            20794..21303
                     /locus_tag="KRL22_002755"
     CDS             20794..21303
                     /locus_tag="KRL22_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH1273225.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
BASE COUNT         8925 a         2210 c         3829 g         7176 t
ORIGIN      
        1 aatattaaaa ataaaaaata tatcaaaaga ttatggaata aaaggattta aaacaaatgt
       61 attaaaaaat atatctctta cagtcaatga aggtgatttt atatcaataa tgggtccatc
      121 tggtgcagga aagacaacat tgctaaattt aatgtctaca cttgacaaac aaacttcagg
      181 agaaataata ctagatggaa ttaatatatc aaaagtaaaa aataatgaac tatcaaaatt
      241 aagaagagaa aaaatagggt ttatatttca agactataat ctattagaca atatgaaact
      301 aatggacaat atagcacttc ctctagcatt aggaaaaaag aaaagtaagg agatagaagc
      361 taaggtattt tctatagcta aaaaatttgg attagaaaat catttagata aatatccata
      421 tcagttatca ggaggacaaa aacaaagagg cgcagcagct aggtcattaa ttacaaatcc
      481 aacagtcata tttgctgatg agccaactgg tgctttagac tctaaatcag catatgaact
      541 tttagaatca ttagaaaaaa taaacagaga aaataacgct actattataa tgattacaca
      601 tgaccctcta acagcaagtt attcaaatga attatatatg ataaatgatg gaaatataaa
      661 gtgtaaatta aacaaaggaa atagtagaaa agaattttat ggaaaaatta tggatatgct
      721 agcctctatg ggaggtgaga tgtaagtgag tatacttgga attgcttata ataattttaa
      781 gagtaatata agaacttatc tagcattttt tatatctatg gttttttcag tagttgtgct
      841 aactaatttt gaattattaa gatatggtga tgctataaat gtgttacaag atgaaaataa
      901 aaaatttaca ctatcagtgt tagtagctgt aataatgata ctatcagtat ttttattttt
      961 ctttatatgg tatgcaacaa atatattttt taagaatagg tctaaagaaa ttggaatatt
     1021 gtcttttatg ggattagatt tatatactat aggaaaaata tattttgtag aaaatatgct
     1081 tataggaata agttcttgta taacaggaat aattataggg ataataacat ctagattttt
     1141 tcaagtagtg ataataaagt tatctggatt taatataaag gtatctaatg gacttagtat
     1201 agaagctata ctatatgcta ctttaatctt tatttctata tttataataa tggctgtaaa
     1261 aggttttata acaatatgta gaagtagtgt aataaatcta atcaatatat ctaaaaaaca
     1321 agaaaaaata ccaaaggtag gaataggtat atatatatta gctatagtat caattatagt
     1381 aataggatat ggctactatc tttctaccaa tataagaact ggagatataa ctagtgtact
     1441 acctgttata ggtataataa tagtaggtac ttatggatta ttcaaatcag ttatgcctgt
     1501 tatatttgat attataatca aaaataaaaa aatattattt aatggaaata atataattgc
     1561 aataaacaat ataaactacc gattaaataa aaactataaa acttatgcta taatagctat
     1621 aattataact acaacaatat caactcttgg tgcttcagtt gcgatgaagc gtatacataa
     1681 gaatgcccaa gaacaaagaa atgtgtacac tattagcata gtttcaatgg ataaagatga
     1741 agtgaataaa aaacaaatag agaatataat aaaagatact aataagataa agtactcagt
     1801 aaatccagaa ctaacaattt taaagaaaac agatataaaa gaagcttatg atacaacaga
     1861 tactataatg aaatatagtg atttttgtaa tactcttaaa gtgaatggca atgataaaga
     1921 attaaaagag tatggtgaaa gattagttag tggaaataat gtaatagagt taaaaagccc
     1981 tcaaacgata gcatcaatag ctacaaaaga agccaagata aaacttgatg gtcagttata
     2041 taatatttca aggggagaag taaaagttcc agtactaggg acaggactta atcaaagtat
     2101 tatagtggta aatgatgata catattttaa actaagagat aagggtcaac aagtgtattt
     2161 ttatggtgca aaggtatttc aagaagaaaa tagtcaagta atgttcaaca atattgaaaa
     2221 gaatttaagt ttaaaaaatg tgtatattca aaatggatat aaagctcaag gtgagagtca
     2281 atggatgaag tttgcatatg tagtgcttgt gtttttattc ttagtctttg caattgtagc
     2341 tggaagtata atatatatga aaatatatag tgatgcatat gaagataaag agaaatataa
     2401 gattttgtta aaaataggta ctacagaaaa agatataaat agagctatac ttaaagaagt
     2461 agctattttt tatactttgc caatgttaag tgcaactata tctagttatt ttgcattgag
     2521 attagcagga gatttattga tgactgattt atttggtata tatatactaa gtttagtgat
     2581 atgtttgata atattcataa tatatggagc agtatctgtt aataagttta agagtgtagt
     2641 gtataaaaat tagttgatat attaataaag agaaaggaga ttcttgtaat aagagtctcc
     2701 ttgttgatta actaaataat ttgggtaata aattcatata aaatatgtta tgatattaat
     2761 aattcatagc atagtgaaat attaggataa tggagaatat acaaatgtat agaattttat
     2821 tagtagagga cgatattgat ttatcaaaag agattgcgtt agcacttgaa aaatggggat
     2881 ttaaagtaga attaattgat gattttgagg tagtattaga tgaatttata gataaaaaac
     2941 cagatgtagt acttttagat gtaaatttac cattatataa tggattttac tggtgcgaaa
     3001 aaataagagc tatttcaaat gtaccattaa tatttttatc atcaagagat tctgatatgg
     3061 atttaataat gggtataaat aatggagcag atgattacat taccaaacca ttttctatag
     3121 aaatattggt taccaaaata aatggtataa taagaagagt ctataattat agtgattcta
     3181 atagtatttt gtattgtgaa gatttgatgt ttgatgtggg gaaagggatt ataaaacata
     3241 agtataagga taaaagtata gagttgacta aaaacgaaat aaaaatttta acattattat
     3301 taaaaaataa gaatagggtt gtatcaaggg aaagtcttat gatgactcta tgggataatg
     3361 atgagtttgt gacagacaat gcacttactg taaatatgaa tagattgaga agtaaagtta
     3421 aagaactagg ttttgatgat tttataaaaa ctaagaaggg gataggatat ataatacaat
     3481 gctagtaaaa tatttaaaag gtaggtctaa gtatattgct ctacctttag ttgtagttag
     3541 tataataaat atctacttat ttgctataga tatttttaaa aataaatatt cagagttaat
     3601 atatttagat tttttagtac tgtttataat aatggtattt tttgttatag attatataaa
     3661 ttttagaaat agttacacaa atttatataa ttgtatagaa aatagtggtg aaatagacag
     3721 ttatttagtt gatggacaat cttttgaaga aaatctaata aaagatatta tagaaaactt
     3781 aaaaataaaa aataatagtg acatagagac ttataaacaa tcattaaaag aattggatga
     3841 gtacatagct aaatgggttc atgaaataaa aattccaata tcttctttaa gtataattac
     3901 agataggtta agtagcatag aagatagttt ggatattaag aattaggttg caaagataaa
     3961 ttttttagta aactctattt tgtatagtag tagaagcaac actatgtttg aagatgtatt
     4021 tataaataaa tttaatttag aaaaattggt aaaaatgtct ataaaaaata attcattttt
     4081 gcttataaaa aataatgtag aagttagttt gaatgaatta gaaaatgatg tttacacaga
     4141 ttctaaatgc atgtcatatg ttttagacca aattattaat aatgctataa agtattcaaa
     4201 ggaagttggt aagattgaat ttaattcaaa aaagttagaa aatagagtgg tattatctat
     4261 aaaagatttt ggtataggta taaatgagga agatatatct agggtttttg acaaggaatt
     4321 tacggggaaa aatggaagaa atcaattgta taagtctact ggaatgggga tgtattttgt
     4381 aaagaaaatg atagatagtt tagggcatga gattgaggta tgttcggaaa atggttcata
     4441 tacaattttt aatatctact tttatgatat atcggattat ttaagcctag atagttaggt
     4501 tattagacta taaaatctat catcatatac aaatcgacat atacaataag aataaattta
     4561 gttcttgaaa atagtgaaga tttaattagt gccttaaatg atgctctatc tatattataa
     4621 aataataatt attatatatg aaaaacatat cagatatgta cctggtatgt tttttatttg
     4681 tagtaactat tttaatatgg tttttggaga gagaatatgt tttgtttgtg aaaaaaaatt
     4741 acatggtatt acattgacac tgaaaataaa ttaatgtaag atttagctaa ggtaaaaaac
     4801 gtgtataaga ttaactcaat taatttcata agagtaaatt atcgtaatta aagatgaaat
     4861 aagattaatt ctaaaattat taaacttaat accttgattt ggggaggaat aactataaac
     4921 ttaaaaggat gataactatg tatagtgtag gtttaatgtc aggaacttcc ttagatggag
     4981 ttgatgcagt actagctgaa attagtggga atggtagaaa tactaaagtt aagcaaatag
     5041 aatttataac tctagaaatt cctaaagata taaaagacga aataagaaag tgctgtatag
     5101 aagaggaatc gagtgttgat ttaatctgta gcttaaattt taagcttgga tatttattta
     5161 gtaaagctgt aaaatcagtg tgtcataaag caaactttca tatagcaaat ttggatttta
     5221 tcgcatctca tggtcaaaca atctttcata taccaagaag ttataataat tttgtatctt
     5281 caacgcttca aataggtgaa ccagcagtta tagcatatga aacaaataca aaggtaatat
     5341 ctaattttag agtaatggat atagcagcag gtggagaagg tgctccatta gtaccatata
     5401 gtgaattttt attatatagt gataacaata aaaatttagc acttcaaaat attggtggaa
     5461 taggaaatat tactataata cctaaatcat gtaacataga tgatgtattt gcatttgata
     5521 caggaccagg aaatatgata atagatggag tatgtcaaag attatttaat agaaagtatg
     5581 ataaaaatgg atactttgca tcaaaaggta aaattaatga agaaatgtta aaagatttga
     5641 tgagtcataa gtatcttagt caagcgccac ctaaaagcac tggaagagag gtatttggac
     5701 aagtttattt ggataacatg cttaacaaat ataaacatgt agataaatat gatttgatag
     5761 caacagtaac tatgtttacg gcaaaagcta tatattataa ttataaaaac ttcatacttc
     5821 caaaggttaa tgtagatact ttattaattg gaggtggagg agctcataat ctaactttaa
     5881 taggatatat aaaagagtta ttattagagg ttgaagtatt aattcaagat gaatatgggt
     5941 attcttctga tgcaaaggag gctttggcat ttgtaatctt gggcaatgaa acattaaata
     6001 attctttttc taatgtaata tctgcaacag gggctaaaaa taaagttatt ttagggaata
     6061 taacacctaa accttttgga ggtaaatgac atgtctaata ataaaaaaaa gaaaagaaag
     6121 aaaagaaaga aaaataataa ttataaaaat gcaaaaagta caaaaagtaa taaaaatact
     6181 aagaaacaaa tggagaaaaa tcaaagaaca gattataata ttccaactat aagttttaaa
     6241 agtggattaa tactaatagt ttcatctctt gtaagtactg tagtttttcc tttgttatta
     6301 tctatatttg gaatagataa tagatttgga gttgttatag gaaattcatt aattacatct
     6361 tttgcagttg catatacaag atactttgtt gaaactaaga gaggtttttc tttgggattt
     6421 tttagactgt atattttatt tgctttatca tttgcaataa taggttactt ctggatatat
     6481 aaaggaatac atatttaaaa aagtattgag actattttat gttaataata agatagtctt
     6541 ttttcttttt taagaaaaga tatgagtatt ttaagtagtg tgtaatttta gacaaaagaa
     6601 tgattagata aataaagcaa ttaaagcaag atataaatgc atgaaataaa attacaattt
     6661 aaaatgtaaa atatgaaaaa atatatacaa acgtattcct gtaatcaaaa atacatgcta
     6721 taatgattga aaagaaataa aaaaacaggg ggaatcaata tgagagtatt atttgtttgt
     6781 tcatcaggga tgtcaagtgc tatagcagtt aatgcattac aaaaagaagg agcaaaaaat
     6841 ggaatagata tagatgtttt ggctgttggt actcaagagt ttgagaatga agttaaaaat
     6901 ggatgggata ttgctatggt agctccacaa gtcagacata gatttgacta tttaaaagct
     6961 tttgctgatg aggttagtgt accatgtgca ttaatacaag cacaagctta tagtccatta
     7021 ggaggaccaa agttattaaa acaagttcaa gaactgttga gtaaatagta gttgcagtgt
     7081 tgttagatta gaagaaagtt aattttataa aaattttaat gataataaaa ataaatatta
     7141 attaaggaga gaaaagatgc tagataaatt tacagaattt ttagacacta aattatcaac
     7201 ttctatggcc agattggcag aacaacgtca cttaagagct gtaagagatg gaatcgtagc
     7261 ttcattacca cttataatag ttgggtcatt tttcttgata ttagcatttc ctccattacc
     7321 agattcatgg ggggtaactc agtatctaaa ggaaaatgca gttacaatat tactaccata
     7381 tagaatgaca ttttttatta tatcagtata ttctacattt ggcataggtt atagtttggc
     7441 aaagtcatat aagttagatg gattgacagg aggtttatta gctacagcta cattcctttt
     7501 gacaatagtt cctactgcaa tagagggtct tacccctgat ttattaaaga tagttgaaaa
     7561 gagtccagaa cttttagctt ggtataattc aattcctcaa ggatggcaaa tgccaatggc
     7621 taatcttggt ggaggttcaa tgtttgttgc tattgtaaca tctataatag gtgttgagat
     7681 ttatagattt actgacaaat ctaaattcaa gataaccatg ccagaagcag ttccagcatc
     7741 agtcacaagg tcttttgaag ctctgacacc agccgcatta ataataattt taatggctat
     7801 tgttacttat ttcctagggt ttgattggca tggcttcata gctaaattag taactccatt
     7861 agtttcagcc actgacacat taccatcagt aattatacta atatttttaa taacgttttt
     7921 ttggtcattt ggaatacatg gtgtatcaat aataggttca ttggcaagac ctttatggat
     7981 acaattatta gatgctaata cagcttcata tgctgcgggt caagcagttc caggtattgc
     8041 tgctgaaccc ttttttcaat ggtttatatg gattggaggt tctggagcta caataggctt
     8101 agctttactt cttgcattta gagcaaaatc agcttatgga aagtctttag gaaaagcaac
     8161 tgtaatacca gcaatattca atataaatga accaataata tttggagcac caatagtatt
     8221 aaacccaata ttaataatac catttgttgt agcaccaata gtaatggcaa cagtttcatg
     8281 gtttgctatg agtgctaatt tagtatccag agtagtagtt actgctcctt ggacattacc
     8341 aggaccagta ggggcatatt tagccactgg tggagattgg agagcttcag ttcttaactt
     8401 attatgtata gctatatcaa taataattta ctatccattt gtcaagatgt acgataagag
     8461 attgcttcat gaagaaaaag ttgaagagca agaagcttat taattagaaa ctatattgga
     8521 aattaaaaac tatattagat tagtataaat ttcaaagtat aacagttatg aaataagtaa
     8581 cgaagatatt ttgttgattg tttataaaaa aagaaaaggt aaacttttct ttttttataa
     8641 atatatatga aacttttttt caccaaattt ttaaaaaagt ttcgtgtaat tcgaaataaa
     8701 tttaaacaca tataggatat aaggagatga cacagatggg aagcttagga atatcaattt
     8761 atccagaaaa aacaacatct aaggaaatat atgattatat agataaagct gctgaaaatg
     8821 gatttacacg tatattttca tgtttattat cagttaaaga tactaaagaa aatataatta
     8881 aaaaatttaa aagtataaat gaatacgcta agtttaaagg ttttgaggta atacttgatg
     8941 taaatcccag agtatttggt gaattagaaa taagctacaa agatttgact ttttttaaaa
     9001 agacgaaggc agacggaata aggcttgata taggatttac aggttctgaa gaggcattaa
     9061 tgacttttaa tcctcaaaat cttaaaatag aaatcaatat gagtaataat actaattata
     9121 tagatacaat aatggactac caaccaaata aagaaaactt gacaggatgt cataactttt
     9181 atccacatag atatagtgga ttaaatttag aacactttat aaaatgtaca gaaagattta
     9241 ataagtatgg attaagaaca gcagtttttg taacaagtca aaatgaaact acatttggac
     9301 catggactgt aactgatggg cttccaacaa ttgagatgca cagaaatcta cctatagata
     9361 ttcaagtaaa gcatataata gctatgaata atataaatga tataataata tcaaattgtt
     9421 atccaacata tgaggagcta aaggtattag gttctatgag aaaagatatg gttacatttg
     9481 atgtagcaat agaggaaaat atacgagaag ttgagaagaa gatactcttt gaagaaatac
     9541 attttaatag aggggacata tctgacagtc tgataaggtc tactcaatct cgtgttaaat
     9601 ataaaggata caaatttgaa ctatttaata ctcctaaaat aataaaaaga ggagatatag
     9661 taattgaaag tagtgaatat ggtcattatg caggggagtt acaaatagcc ttgactgata
     9721 tgaaaaacag tggtaaatcg aatgtagtag gatatataag aaaagaagaa ttatttatat
     9781 tagattatat taaaccatgg caaaagttta attttaaacc ctcaacaaaa taatttatta
     9841 tgaaaatatt aatttattat aaaaatataa ttatgaaagt tggaattaaa atgtgtttaa
     9901 aaatttaata ttaagaaaat gaggaaatga tatgttaata aaaactttag aaaatttagt
     9961 tacagaaggt agaaataaga atacattgca aatagataaa gaagatacat taggcataat
    10021 agaattaata aataacgaag ataaaactgt agcctatgct gttgaagaac aaaaggagag
    10081 tatagcaaaa gctgttaata taatagtaga tagaatgaag cagggaggta gattattcta
    10141 tataggagca ggcaccagtg gtaggatagg aatactagat gccacagaat gtcctccaac
    10201 ttacggagtg gattttgagc ttgttcaagc tataatagct ggtggaaatc aagcaatatt
    10261 taaagcaata gaaggtgctg aagatgataa agaacttgga aagcaagata taatagatag
    10321 aggagttaca tctaaggatg ttatatgtgg tatagctgca tcaggaagga ctccttatgt
    10381 tataggtgca atggagtatg ctaaggaatt ggggtgtgca gtactatcaa taactatgaa
    10441 tccgaatagt gaaatgagta aaaaagcgga tttaccaata aacattatag taggggcaga
    10501 agtaataatg ggttcaacta gaatgaaaag tggtacagct caaaaaatgg tatgtaatat
    10561 gttaacaaca gcttctatgg ttaagatggg aaaagtatac tcaaacttga tggtagatgt
    10621 taagacatca aatgaaaagt tggttgaaag agcaaaaaga ataataatga tagctacaaa
    10681 tgtaaaatat gatgttgcag aaaaattctt agaagaagca gataatagcg ttaaattggc
    10741 tatatttatg ataaaaagtg gtttagataa ggatagtgca aagagtatcc tagatagaca
    10801 agaaggttat ataagtgaag ctttaaaatc aatagaaaaa ttgtaaaata aataatagta
    10861 ctgataacct ttcaatatta aaaaaacagc attggaaggt tatttttaga tattaagtat
    10921 tgaaagaatt attaaagata ttgtaggagg atagtatgta ttttttaggt gtagatggtg
    10981 gaggaacgaa aacaacattt acattagtag atgaagaatt aaatatagta ggaaccataa
    11041 ccaaaggaac ttgtcattat aatcaaatag gatttgataa tctaacgaaa ttattaataa
    11101 ctgggttgga agaagtttgt aaagatgcta agataaatgt agaagaaata acgtatgcat
    11161 ttgttggact tgctggatat ggaaaaataa aagaagtatt gtatgcatta gaagtagcaa
    11221 caaaaaatgc atatagtcat ataaatttac tctaggtaat gatgtagaaa tagcattagc
    11281 aggttcttta aatggggaaa aaggtataaa tataattgca ggtactggtt caatagcaca
    11341 ggctttagat aaagatggga atcttcacag atgtggagga tggggctatg tattaggaga
    11401 tgaaggttca gcgtattata taggaatggc taccttaaaa atgttcacaa tgcagtctga
    11461 tggaaggtgt tcaaaaacaa aattatatga tttaataaaa agacatctta atatagagaa
    11521 tgattatgac ataataaaat atgtaaatga tgaaatacaa ggagatagaa tagaaatagc
    11581 aaagtttgct acgatatgtt taaaagcagt tattgaaggt gataatactg ctagtaaaat
    11641 atttgatgat gcagcttatg aattaagtag gcttataata ggattagagc atcattttga
    11701 acaaggtaca aagataaagg tatcttattc aggtggagtg tttaagtcag gagatttaat
    11761 attagagcca cttaaaaaat atttgaataa aacgagattt ggtatagtga gaccagtgtt
    11821 gactccagat ttaggagcat gtttacttgc taagaagaaa tattatagta aataggtaga
    11881 ggtgatagag tatgagttgc attttaaaat taaaacagat atatgaagat ttaacggaag
    11941 tagataaaaa aatagctgat tacatactta ataatacaga ggctataagt aagctttctg
    12001 tatcagaatt ggcgtcaaac tcaaaaacaa gtacagcaag tatagttagg ttttctagaa
    12061 aaatgggata ttcgggtttt ggggatttaa aaattgagat agctaaagat ttgatgggca
    12121 aagaaaatga atacacatat gtagatgaaa actatgattg taatatagat agtgttataa
    12181 acaaaattac aaacaaaaac atagagacta tcaaccaaac aaggttgttg aatgaaaaag
    12241 atataataaa agaagcagtt gaacagataa taaaggctaa aaatgtatat atatttggag
    12301 taggtggttc ggctttagtt gcactagatt tacagatgaa acttttaagg ataaataaac
    12361 aggcatttac ctctttagat agtcatacac aacttatggt atcttcaaat gtagataaag
    12421 aagatatagc tatagcaata tcttactctg gagaatcaaa agaagtaata aagtctatag
    12481 aaaatgcaaa attaaaagga tgtaaggtca tttgtataac taaatatagt gacaatcatc
    12541 ttagtaagat tagtgattta aagctagtag taccaaatat agaaaaaaga cttagagaag
    12601 gagctatttc ttcaagaata gcaatgctta cgttgataga tataatatat atttctataa
    12661 ttcaagaaaa cttaaatgag gcagaacaga aactacaaga aacaaaaagg atacttgatt
    12721 atttaaatat taataatgct taaaactagg ttatatatca actaaacaaa taagttaggc
    12781 tataagcgta agtcaataag aaatagataa atatctaaaa tattgactta cttaataata
    12841 atatatagca tttttataat acaaatgagt tgtcttaaaa ttgatttttt ttaatcaaat
    12901 tttaagttca actccttttt tatattttta tagatatatc ctatattttc ccagaaaacg
    12961 tattgaatat acaaattata agaagtataa tgttgttggg agagaatgta tgaaatgtat
    13021 acaaagttga ttttaactgt attattgata attctcttta ctcttaccat tattaatgat
    13081 tgaagacaat ggtatttatt ataggtcaaa gattccgaat gtattaatca tcatcatttt
    13141 ctcaaactaa cagcaaatac cctgatttgc gagttgtatt gtatacaaat tatctagaaa
    13201 atatctatta gattttccat aaaatttaaa tatttcacga atgtatgaat ggagaaatat
    13261 acatgttgac aatccacctt tttaaatcct aaattaattt tattaatggt agagaatagg
    13321 aagtaacaat gttttataaa ggagaatatt aagtatgaag aaaattagga agttaactac
    13381 aaagttattg attacaacaa tagttttaat ctcaggtatg agtatgacag tttatggtat
    13441 gacagccaaa gaggtaacag caaaaacacc aaaaagctat gtcactggaa ccaatagcgt
    13501 atatggtcca aagctgtcac aagcccaact aaactcagta gcacaagcaa cagcagattt
    13561 tatgaacaag aaaatcacaa agaatatgac cacagatgct aagattttag ttgcctacaa
    13621 tcacattaaa aataacacaa catatgttga ctggaatgca gtagagggag caaatactgc
    13681 ctatacattg gttactaaaa aaggtgcatg ctcaggaatg gctaggagca tgaaagcttt
    13741 gtgtgatgct atgggaattg aatcttatta tgtacacagc acatcaaatg accaccagtg
    13801 gaatcttatc cgttttggtg atgggcgttt gtatcatgta gatattgatg ctaataaatc
    13861 agcaggaaag gatatcatat acaagagtct tagccaccca ttaccatttg ataagacagc
    13921 atatccaaaa gttggtgcaa tagtacagac ggtaaaacca gaacagacac agaaaccagc
    13981 accacctgga aagcacacta tgttaccaca tcaagaaggg gcaaaggctg ttggaaattt
    14041 tggaaaaaaa ggagaagata taaatgaaaa acatgtaatg tatgaaggtg ttagatgtag
    14101 tgtagttaat tcatcagtaa atacaattac atttacaggt agtgaatcaa atttagaccc
    14161 atcaaatctt acgattgctg taataggatt tatgaacaca ccatatggga tgtttgcatt
    14221 agcaccagag ggtaaacctg ttgaatatcc ttttaaatat gataagccat tttctttaga
    14281 ttttagtggt aaaaatcgtt ctggtgcaga attagcgaag tactgtaaaa aaaatgatgt
    14341 gactattaaa atagaaatca ctgatgaaaa agctaatatt ggacttggtc aaataatgta
    14401 tgttcgatat gaataatgat ttaatcatga cagtagaata agttataaac attgcgccct
    14461 cttactaggg gcgcatttaa tattatatct gatattttgt agtcaggtca actgctagat
    14521 ttctcccctt tttatttata aaaattatta tctctaagca tctgagcatg tttacgatta
    14581 actaaaaact gttttaactc agtcaagcat aggaataaaa tagctctatt ttcaaactct
    14641 gttctgtcaa caggtagagg ctggtttttc atactaagca ttagtctctt taattcttca
    14701 agaagaagat tgcctgtttc agcttcaaat tcagtataac ctatcttatg tataaaagca
    14761 gatagaatat gagcttgtgg tggtgtagaa tttagttgag atacataact atacaaattt
    14821 tctaagatat cccgttgact ttttataata tccatatgct ctaagaagaa tctagtatca
    14881 cttaataaag tattattaat attatcgtaa gtttcagaaa tactgctgtc aataagtgaa
    14941 tttaatgtat ataaatctct actatatcca ttttcttttt taggatttac aataatatct
    15001 gcaatgtcta taagtacaat actcacttct tcctgtaact ttttttgaac ttcatggatt
    15061 ttatgtatat ttgttgggat atacatattt attaagacac ctattccagt tcctactgca
    15121 aatattccag cttcatttaa aatccatttg atagaagttt ctccttgaag gtagtaatgg
    15181 gatgctatga ctacacacat agcaataaca tcttgaatat ttagcaaaaa acaaagtggt
    15241 ataattataa atataaatat tgaaaatgaa gtcaaattat atcctaaaat attaaaacat
    15301 aaatatgaaa aaatagtaca taaaagaaaa ccataaatct ttccaatgga gcctttaaga
    15361 gtttctcttt tagtgtcctt tactgtaagt agtactataa ctccagcaac cattgagtat
    15421 tctaatttta atagccaagc aataaatata gcaagagaac atccaagaga taattttatt
    15481 actttaagtg aattaatatt attcaaatgc aaacctcctg taaatcaata taataaaatt
    15541 ctaacataaa actaatattg cttgaaaggt aagtaactat acttaattat tttattgccc
    15601 tatttgttta gatacaatca atataatttt attttatgaa aattttttgt aaaattttaa
    15661 atttagagac taacatgaga ccacaaagag gaagtttatt ataagaagaa aacttaaaat
    15721 tgattttaaa tagcaaatga aaataatcaa atatgtatat actattatta aaaaataaaa
    15781 ttatatagtt aatataattt tataattggt ttagtataga gatttttaac ttttatgtta
    15841 tactatttat aaaagtaggt ataaagatta aaatacataa tcaaatatgt ataagaggtt
    15901 ttaaatagta ttgttaatga acttgattat tgtttataat tacaaattgg aggagataaa
    15961 catgaaaatt actgaaggat atatgccttt taaaggtttt aaaacgtatt accgtatagt
    16021 aggagaaaat acggaaggga agaagccatt agtattactt catggaggtc caggttctac
    16081 acacaactat tttgaggtat tggataagat agctgaaagt ggtagacaag taataatgta
    16141 tgaccaaatt ggttgtggaa attcatttgt agaagggcat cctgagctat ttaatgcaga
    16201 tacttggata gaggagctta ttgaactaag aaaacatcta ggacttgatg aaattcatct
    16261 gttaggtcaa tcttggggag gtatgcaggc tatttggtat gctattgaat ataaaccaaa
    16321 aggtattaag tcttacatcc tttcatctac tctttcttct gcaaaacttt gggagaaaga
    16381 acaaaaaaga agaatatcat atatgagtga ggttgaccaa aaagcattac ttgatgcagt
    16441 aaatactgga gattactcta gcaaagaata taatgatgca ttagaaagat ttatggaaat
    16501 gtattgtgca ggtgaagtga cagaagattc tccagagtgc ctgagaagac ctaaaaaatc
    16561 aggttctgaa gcatatattg taggatgggg acaaaatgaa ttttctccta caggaactct
    16621 ttctggatat gaatttacag atagattaca tgaaataaaa gagccttgtc tagtaactag
    16681 tggagcaata gatttatgtt caccatatat tgcaaagact atgtatgata gaatacctaa
    16741 tagtaagtgg gaattatttg agtattcaag acatatgcca ttcgttgaag aaaatgagaa
    16801 atatataaaa gtcttaactg agtggttgaa tgcgaacgat taaaaactat ataaatttat
    16861 ataaaaaaat gagtgtctca aaatgaactt tttagttcat taggcactct ttttgcatga
    16921 aatcaaatat attttcatta tttgaacgat aaaatgaagc ttatatctat tttgggaaag
    16981 taatttttta ttactagcgt tagattctaa tctaattgta tacttattga aataatagaa
    17041 atatattggt gtttataact taattttatt gttttttaga aattttttta tatattggta
    17101 taattattct gtttaaattt gattaaaaag tatattaatt ataataagaa acaattatat
    17161 aaataggaat agattattat aattaatata gatataaaaa taattataga aggaaaggca
    17221 cattatggaa aaattgagag ttattgaaat gataaaaaat aatcccaata ttatagctac
    17281 aatagataat ccaactgatg aaatgaaatt gttagctatt aaagaaaatg ggcttgtact
    17341 agaatatata aataatccaa ccagagagat gcaagaacta gcaatagata ataatattag
    17401 agcaattaaa tttatagata atccaacaga agatatgatg ataaaagcag taaatgaggg
    17461 atggagtata ctggattata tcaaaaaccc aactgataaa gttattgaaa tggctataaa
    17521 tcaagcagga tgggcaatta aatatgctaa aaatccaagt gaagaattac aactattagc
    17581 agtaagaaaa aattatgatt cgataaagtt tataaaacaa ccttatgaaa gtgtacaaga
    17641 ggaggcagtg agaataagtt atgatgcctt gagatatata gattcaccta gttacaatgc
    17701 agaacttata gctataaaaa ataatgaagc agctattagc tttataactg atttagataa
    17761 aaataaaatg ttggaatttt taaaagtgaa tattttagtg attaagtaca ttctgaaaaa
    17821 agtatctaaa gatgaattag agagtgtatt aaaagaagta ttatccaaag aagatgttga
    17881 ggaaaagtat attagagatt ttttgaattg tagtgttata gatagaaata gcgaaagtat
    17941 accaatagat aaaattatgt ttatttataa atatggaagt aagacagcaa aaaaaatagc
    18001 tgtagatgag aaattaaaga ttatgtagga gagagaaaaa tgaattttat agacacatta
    18061 aaaagcgttg acttaatatt atccactgga gaagtacctt taatagtagg tgaaagtgga
    18121 ataggaaaaa cagctttagc aaataagctt gccaaagaaa atgattggag tttaattgtt
    18181 attgatggaa acttacttaa agagggtgaa ataggtggtc ttccaactat agaatcttat
    18241 gtaggagtta attctaatgg atataagact gaaaagaaaa caacagtgta tgctgttcat
    18301 aacaaattaa gagaaattga tgaagagata tctaaaagta agacagttct tttatttata
    18361 gatgagataa atcgttgtga gcatacagta cagcaagaac ttatgaattt aattttaaat
    18421 agagaaatta atggatataa actgcatgat gatgtaaaga ttttagcagc aatgaatcca
    18481 tcaagtaaat atggttcaga ttttgattat caagtggtag atatggatgc agcccaagaa
    18541 aataggtttg tttggttaaa tatggagagt gaccatacac aatggataaa atgggcaata
    18601 gatgagggta ttgaaagaaa agttatcgag tttatttcca cttttccaga atatctgcat
    18661 aaaataaatg aagatgatgt aagagccact cctagaagtt atgagagagt atctaaaatt
    18721 tataaagttt ataaagaaaa aaataattct attcctagag cagtattttt aaatgttgta
    18781 aagggtaatg taggtaaagt tattgcagaa gaatttataa gttttattga atcaaactct
    18841 gaaccattaa tatcctatga agatgttttt ttaggagaat ctattgatga gtctattgta
    18901 gaaagagtaa aaaatgagag tcatacaaga ctttatctat cagctatgaa cattctaaaa
    18961 gacttagaat taaatattaa gaatgataaa tatgaatcaa accactatat taatagattt
    19021 attgaatttt taaaaatgta tcctgtagat ttaatgatag gtattatgaa ggatattaga
    19081 aacagttata ttgaagtata taaaaaagct atagaaaatg aagagtttgt aaaatcatat
    19141 tttgaatctt atagtttaat aaggggataa tgtatggaaa attattttga taaacaagca
    19201 aaagagcttt ataataaagc aagtgaaatt ataaatactc attctatgct aaaggcaaat
    19261 cgtgctaatg agaaatttga tatagatata ccacaagatt ttaagtatga gttttttagt
    19321 cttgtagata aagtgaattt aagtcttatg gaagaagaag ataattttta tggatatttt
    19381 ttgtttcaga tgtcaagaga aataagattt gatataagta gtcctacagg tgtgaatttt
    19441 aagggagcta aatatgttat atattttaat ccaataatct ttttaacgct tgacataaag
    19501 caaatggaga ctacaattaa acatgaaatt catcatatat tatctatgca tttgatgaga
    19561 gcaaaggagt taaaaggaaa gtatagtaca ttagcaatta atatggcaat ggatatagta
    19621 gtaaataaat ttctaaacaa tttaccacca tatgcaacta ccttagagtg ggtaaattta
    19681 aagtattcct taaaacttga accatatgaa ccttttgaat attatgtaga aaagattcag
    19741 actgaattag atttgatgga agtggatgaa gatggtgagg aagatgatag tgataaatat
    19801 ggagatatag aaattgatta tagccccgaa agaactcatg atatatggga tgaatccaat
    19861 gagatagatg aaaataccct tagagaattt actgaaaaat ttattaacag ttctcaaaaa
    19921 ggtaaagttc ctgcttattt agaaagtatg atatcatcac ttaaaaatag taagggtgaa
    19981 ttgccatgga atttatatct taatagaata atgggaacag ttgaaaataa taaaaagaag
    20041 actataacaa gaagaaatag aagacaacca aatcgtttag atttgagggg agaacttaga
    20101 agtcataagt cagaaatagc agttgcactt gatgtaagtg gaagtattag tgatgaagag
    20161 tttaaacaag ctattaaaga agttcttagt atagtgaaaa actataatca tgaaattaca
    20221 attatagaat gtgataatga aattagacgt gtatataaag tgagaactga aaaagatata
    20281 aaagatagaa ttaggatagg tggaggcact agattttctc cagtctttga gtatgctaat
    20341 aataaaaaga ttaatttgtt agtctacttt actgatggta aaggtgaaaa taaactacaa
    20401 gtaataccta gagggtataa aattttatgg gttatttctg gaagaggaga taaaatttca
    20461 ttaaaagaac cttatggagc agttaaaaaa cttactaagg ttaaaacaaa tgatgaaata
    20521 ttagaaataa atgatgtaag aaatgatggg tactcaatga atagccaagc accaatttta
    20581 taggtattca caggagataa gctttattaa tttattttga tatgcttgtt ataaaaatct
    20641 aaaaaataca ttaatcaatg gttaatgtat tttttaattt taataatata agttttactt
    20701 acatttaagt cttaaaatgt gttaaaatat aatatatagc agatagtttt ggcaaggtgg
    20761 atttagttgt caaaactatt ttttttatta aggatggtga tgtttttgtt taagattgat
    20821 gattatataa tgtatggtat gacaggagtc tgcaaagtca tggatataac aaatgaacga
    20881 tttacaaatg gaataaaaaa agagtattat gtattgagtc ctatttattc taataataca
    20941 gtaataaaaa ttcctgtaga taatgaaaaa gtaccaatga gaaagttact ttctaaaatt
    21001 aatgtgcttt cattaataaa tgatattcct aatatggata catcatggat agataatgaa
    21061 aaattgagaa gtgagcaatt taaaaaaata ctcagaggtg gtaaatgtga agagttaata
    21121 aaattagtaa gaagtataga taataacaga gagtatgtaa aatctattgg taaaaaaaca
    21181 catcaagcag atgataatat aatgaaagaa gctgaaaggt tattaaatga agaatttgca
    21241 actattttag atatttctcc taatgaagtt agttcatata tttcaagtca tatacctcaa
    21301 taaagtgttt tagtatcctt tatttaatct attttaagta ttatttatgt atgctggttt
    21361 tggtaaaata aaatatataa ttaaattata taaaaaataa taatgattgt attgaagaat
    21421 tacagaatag tgcggagagc ctactccttt aggtgtgaga tggatatcac ttaaagattt
    21481 aaattgttat tgtagatgtt tttaatataa aacaagatta ataagtgtat tgtaagcttt
    21541 aagtgaaatt gatactataa tgagttactt agattttaaa atatataata ttataaaaaa
    21601 tccttttagg ttttgaatga ataagatgga tactatgttg aatagaatcc atcttattta
    21661 agttttattt atgttgttta tttgtaagca ttatttttgt acatgaaaac acagtgtaaa
    21721 aatatgctta gaattatgaa gttttattaa aaagatattc gacaaaataa gactaaaaat
    21781 attcttaaac ttataactaa gataaatatt gtatatttat agtgtagcct gaaaaattgt
    21841 gaatgtacga aatttattta gtattttatt gaaacaaagt agaagaagta ctatagttta
    21901 tctttgaata gattgttatt ttttagtgaa aaagttatta ggttaataca taaatataat
    21961 agcttataaa tagtttaagc atgttaaaaa agtagttatt agagatatat agttacattg
    22021 cttataagat acttaaaatg atagcattca cttatattta gaaaattaag ataaaaaatc
    22081 atttttatat agtaaagcat acctaaattt agaaaataat tgaatttata aaattaatta
//
LOCUS       DAEPUT010000068        21120 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.070, whole genome shotgun sequence.
ACCESSION   DAEPUT010000068 DAEPUT010000000
VERSION     DAEPUT010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21120
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.070"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            226..1212
                     /locus_tag="KRL22_002756"
     CDS             226..1212
                     /locus_tag="KRL22_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1273226.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1632..2483
                     /locus_tag="KRL22_002757"
     CDS             1632..2483
                     /locus_tag="KRL22_002757"
                     /inference="COORDINATES: protein motif:HMM:NF012703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginase family protein"
                     /protein_id="HBH1273227.1"
                     /translation="MKTIRLLYPDYVSGGLEQYFFGANLMSHILPENENQPIVKVEIT
                     PPNRKEKLVTDGIYGKNEVIAGIKNATEKIEKENPDKIITIGGNCLVSQAPFDYLHGK
                     YNDLGIIWIDAHPDVSTVNDDYPNAHAMVLGSLMGYGDNALSSLMKNKKFKADEILYV
                     GLQEIHDYQKKFLDETCVNYKIQTDEFLSDKEILSFIERFENIVVHFDIDVLDENLFH
                     STYFANPDLVGDGSGGGKMTLDKLGNILHCITENSNVVGFTIAEYLPFDEYKLHKLFS
                     KIRMFTE"
     gene            2827..3084
                     /locus_tag="KRL22_002758"
                     /pseudo
     CDS             2827..3084
                     /locus_tag="KRL22_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008790768.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            3241..3666
                     /locus_tag="KRL22_002759"
     CDS             3241..3666
                     /locus_tag="KRL22_002759"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1273228.1"
                     /translation="MSEETENAFRRVLKRKQKPTLKDIDGYRNFLFISPNGNPMQESN
                     YKSVLNGVVKKYNKNHEKTPLLKITPHSLRHTFCTQLVQKNMNPKNLQYTMGHASITI
                     TLDLYAYASEAGANRELRKHDSMIYNDLYNYCEQKYKGL"
     gene            4079..5560
                     /locus_tag="KRL22_002760"
     CDS             4079..5560
                     /locus_tag="KRL22_002760"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBH1273229.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKIKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENNENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDKSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NDGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            5586..6557
                     /locus_tag="KRL22_002761"
     CDS             5586..6557
                     /locus_tag="KRL22_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HBH1273230.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEANVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(6813..7415)
                     /locus_tag="KRL22_002762"
     CDS             complement(6813..7415)
                     /locus_tag="KRL22_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1273231.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILSNSIELDNC"
     gene            7696..8907
                     /locus_tag="KRL22_002763"
     CDS             7696..8907
                     /locus_tag="KRL22_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HBH1273232.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            8975..9172
                     /locus_tag="KRL22_002764"
     CDS             8975..9172
                     /locus_tag="KRL22_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HBH1273233.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            9206..10177
                     /locus_tag="KRL22_002765"
     CDS             9206..10177
                     /locus_tag="KRL22_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1273234.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            10364..10741
                     /locus_tag="KRL22_002766"
     CDS             10364..10741
                     /locus_tag="KRL22_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1273235.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
     gene            11272..11931
                     /locus_tag="KRL22_002767"
     CDS             11272..11931
                     /locus_tag="KRL22_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH1273236.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIKIRKI
                     R"
     gene            12225..12566
                     /locus_tag="KRL22_002768"
     CDS             12225..12566
                     /locus_tag="KRL22_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBH1273237.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            12717..13130
                     /locus_tag="KRL22_002769"
     CDS             12717..13130
                     /locus_tag="KRL22_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HBH1273238.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            13332..13973
                     /locus_tag="KRL22_002770"
     CDS             13332..13973
                     /locus_tag="KRL22_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH1273239.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            13997..15250
                     /locus_tag="KRL22_002771"
     CDS             13997..15250
                     /locus_tag="KRL22_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1273240.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            15296..15946
                     /locus_tag="KRL22_002772"
     CDS             15296..15946
                     /locus_tag="KRL22_002772"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBH1273241.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNAKEVIQTAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKSSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            15997..16593
                     /locus_tag="KRL22_002773"
     CDS             15997..16593
                     /locus_tag="KRL22_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH1273242.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            16606..17445
                     /locus_tag="KRL22_002774"
     CDS             16606..17445
                     /locus_tag="KRL22_002774"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBH1273243.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            17690..18844
                     /locus_tag="KRL22_002775"
     CDS             17690..18844
                     /locus_tag="KRL22_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HBH1273244.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDRYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            19150..20847
                     /gene="ade"
                     /locus_tag="KRL22_002776"
     CDS             19150..20847
                     /gene="ade"
                     /locus_tag="KRL22_002776"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBH1273245.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGASAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKLYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMEVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
BASE COUNT         8492 a         2258 c         3560 g         6810 t
ORIGIN      
        1 taaattaaag tatttatcaa ttcatagtag ataaaattga aattaaatat aacaacaaaa
       61 aatgaaaatt acaattaatt taatgttaaa gactcaattc tttggatgtg gatatggata
      121 gtacaagtag tatataaaaa gtattgactg gacaaataac tatattttat tttaaatata
      181 taatataatg taataaaata tatcaaatgt agaaggtgat aacctatgaa aaaaataaca
      241 ataaatgata ttgctaactt ggcaggagta tctaaaagta ctgtatcaag atatctaaat
      301 aataaagata tcagtgattc tactaaagag aaaataaaga caataataga tgaatatgga
      361 tatgagccga atgcatttgc tcaaagtttg agagctaaaa aaacatactt tattggtatt
      421 ataacaccgt gtttagattc ttttgtaaaa tctaaaatta tgatggcaat agatgaagaa
      481 ctcaaagaat taaaatatac atcactaatt attaatacta atagaaaaat aaggtcagaa
      541 atagatagta tatcaaagtt agctagtcta aaagttgatg gaataatact aattggtacc
      601 gaaataacta aagaacataa gaatgaaatt gaaaagttag atataccgat agttgtagtt
      661 ggacaaaaag ttgatggtat caatagcata gtgaatgatg attatggagc aggatataaa
      721 atgggtcaat atattgctaa taaaggttac aaaaacattg tatatttagg tgttgatgaa
      781 agtgatatat cagttggttt aaatagaaaa aatggagtac ttaatgggtt aaaagataaa
      841 gggtatgatg caaaagtatt ttatactgac tttgaccaag aaacgtctat acaaagaagt
      901 ggagaaatgc tagaaagtga aaatccagat ataataatat gtgcaactga taatatagca
      961 atagcaacaa tgaaagaaat caataagaga ggtaaaagta taccacaaga tatatctgta
     1021 gctggatttg ggggatatga tgtattgtct attataagcc ctaaacttac aacaataaag
     1081 tttgaaaata aaaatgcagg taaagtagca gcaaatacga tagtaaactt aatacaagaa
     1141 agaaaagaac cactattaaa ggagattaaa tttgaattaa tagaaggtga aagtacaata
     1201 aataaaaatt aagatacaca ttacatatat tagtaatgtg tattttttta ataaaaacag
     1261 atagaaaatc gaaaatatcc acataaatac agtatctatc aacaaaacaa ccaaaagaaa
     1321 acacggaaaa ttagaacaaa tgaaagagcc ttatgtaacg acttataaag agaaatacaa
     1381 agatataaga aaacggcact tgaacagagt gtctttttct atgcagtgga acagcatact
     1441 atttcatttc tgcttgatta ccttaaaact tattagtcta tggtttgtca atggcttatt
     1501 gcgtaagcaa tgttgaatag catcctttac aaatcatgga ctggtaagta acttttcaaa
     1561 agcagaaaag aaatgacgat aaaaatatat catgctataa ttgaagaaaa ttataatttt
     1621 aggaggatac catgaaaaca atacgattat tatatcctga ttatgtgagt ggtggtttag
     1681 aacaatattt ttttggcgca aatttaatgt ctcatatttt gccagaaaat gagaatcaac
     1741 ccattgttaa agtggaaatc acaccaccaa acagaaaaga aaaattagtg acagacggta
     1801 tttatggaaa aaatgaagtt atagcaggaa taaaaaatgc cacagaaaag attgaaaaag
     1861 aaaacccaga taaaataatc acgattggtg gaaattgttt ggtttcacaa gctccatttg
     1921 actatttgca tggaaaatac aatgatttag gaattatttg gatagatgca caccctgatg
     1981 tttcaacagt caatgacgac tatccaaacg cacatgctat ggtacttggt tctttaatgg
     2041 gatatgggga caatgcgttg tcaagtctta tgaaaaacaa gaaatttaag gcagacgaaa
     2101 tattatatgt tggacttcaa gaaatacatg attatcaaaa aaaattttta gatgaaacat
     2161 gtgtcaatta caagatacaa acagatgaat ttttatctga taaagagatt ttgtcgttta
     2221 tagaaagatt tgaaaatata gtcgttcatt ttgatattga tgtacttgat gaaaatcttt
     2281 tccattccac ctattttgca aaccctgatt tggtcggcga tggttcaggc gggggaaaaa
     2341 tgacattgga taaattagga aatattcttc attgcattac agaaaattca aatgttgtag
     2401 gatttacaat agcagaatat ctgccttttg atgaatacaa actacataag ttattttcta
     2461 aaattcgtat gtttaccgaa tagcttattt gattaacgtg gaatatttca aaccgacgga
     2521 gtggtccgcc cactgtggcg gtcgtaagac atatcgcaac tggctagggg tggttcactt
     2581 cggcggcttg gcaagcgaag cgagccttat aagccccgtt atctaacagg gggggactat
     2641 tacaagaaac aagagacaga acaattacaa aaatcccgat atgcaacgat ttataaggtt
     2701 ataagcactt actgtacttc gcaccttgtc aattggtgga aaacagtata tcgacagcaa
     2761 gaaaatacat gatacaaggt gtatgctcct atgggcgtat gccttttttg attggaggaa
     2821 taaaacatga atgacattga atttattgaa gcattgaaag aaaagcggaa cgcctgcggt
     2881 tattcccaaa caagactgcc aaaggaactg cacatcagca ggcaaaactt aaattattca
     2941 tgaagattac ggactgtttg gctatgaaga acaatatatc tatggagaga ttatcgttac
     3001 agcttctaaa gacgtttcta tgggcgtttt acggaattga ggggtatggg ctgtcggcac
     3061 ttggaacacg tcttacaggc aaggaaaaca ggcttgcgta tctcggagct ttgcggactg
     3121 acaaagaatg atttggattt caagaaccat gtaatccgta tcaatcatca gctacttaaa
     3181 gataaggacg gtttctacat agcatagcca aagacaaaga gcagtttccg caacgtgcct
     3241 atgagcgaag aaacagagaa tgcctttcgc cgagtgctga aaaggaagca gaagccaacg
     3301 ctcaaagata tagatggcta ccgcaatttc ctattcatca gtcccaacgg aaaccctatg
     3361 caagaaagca attataaatc ggtgctgaac ggtgttgtaa agaagtacaa caagaaccat
     3421 gagaaaacac cgttgctgaa gataacaccc cacagcctaa gacatacgtt ctgtacacag
     3481 cttgtacaga agaacatgaa cccgaaaaat ttacaatata caatggggca tgcaagcata
     3541 acgataacgc tggacttata cgcctatgcg tcagaggcag gagcaaacag agaattgcga
     3601 aagcatgata gcatgattta caacgatttg tacaactatt gcgagcagaa atataaggga
     3661 ttatgaccag ttccacagta tacctgcaac atgaaaaaaa cgctagaccc ttataaacag
     3721 ggatatattg acggttcgtg atagttataa aaaaatacta aaaaatctat gctgtttttt
     3781 actaaaaaac tataattcta aaaattagga aaactttttt gaaagaaata ttgcatctga
     3841 aataaattta tgttaatctt taattaaacc ggtttcgaaa ccggtttaat taaaccgata
     3901 gaatagcaaa atgagtgcaa aaataactga ttgttacaaa gtatcaaagt aattattaga
     3961 gtacatagga aataaataaa atataaaagg tgtagcacat tgtgtaataa gactaagaat
     4021 tgttttagat agcaataata aagcaaatat aaaattataa aagaaaagga ataaaaatat
     4081 gtacaaagag cctaaatata gaaccatatt agaatcgaca aaagaagaat taaataaatt
     4141 aagaaatata tctttaaatg ataaatataa accactattt catatacatc cacaacatgg
     4201 actacttaat gacccaaatg gattagcata ttataatggt aagtatcatg tattttatca
     4261 atggtatcca tatgatgcaa ctcatggaat gaagcattgg gcttatgtaa gttctgatga
     4321 ttttgtaaac tggaatagag aagatgtagc attaatacca atcgaaagtt atgaatctca
     4381 tggagcatat tcaggtaatg cgatagaggt agatggaaaa ttgcatatgt attatacagg
     4441 gaatataaaa tatagtgcag aagatagata tgcatatcaa aacttagcta taatgaacaa
     4501 ggatggtaaa ataactaaat atgaaaataa tccaatagta agtgaaatac caaaaggata
     4561 tacaggacat gtaagagacc caaaagtatt taaaataaag gataaatact ttatgttact
     4621 tggagcacaa acaagtgata aaaaaggagt tataatagta tatgaatcta aaaactctat
     4681 agattggaat tttaaaggag aattaaatgt aaaaaatata gatgaagatt ttggttacat
     4741 gtgggaatgt ccagattata ttaatataga tgaaaaagat atattaatat tttcaccaca
     4801 aggagtagaa cctaaaggat ttgattatca aaatatatat aatgtagtat atgctattgg
     4861 taatatggat ttagataatt taacatttga aatagataca atgaaagaac tggaaaaagg
     4921 atttgatttc tatgctccac aaacatttat aaaggactca caaataatac tatttgcatg
     4981 ggctggaatg ggagaagttt tataccctac agataaaaac aaatgggcac attgtctaac
     5041 tgttccaaga aaattaaata taaaaaataa taagctattg caaatgcctg tagatgaatt
     5101 aattaaatta agatatgatg aaacaagtgg gcaaaatact ataaagaata atatcaatat
     5161 tatagaaaat aatgaaaatg tatatgagct taatattaat ataaaaaata ttgacagcaa
     5221 taaatttggg ctggaattat tttcatcaca agatgaaggt gtaaaattag aatttaacaa
     5281 attaggaaac attgtaactt tagacaaaag caactttaaa aaagttttcg gtgttgaata
     5341 tggaacaaat agaaaagaat atataaatat tgatgaaaat actaatatca aagtactagc
     5401 ggatagaagt attttagaaa tttttataaa tgatggagaa gtagtattta ctagtagaat
     5461 atttgctaaa gaaaattcta atcaaataag ggtttatagt gataaaatag tagagtatga
     5521 gtatactaaa tttaaattaa agcaaggtat tgaattataa aaacacatta taaggggtag
     5581 aaaagatgaa aaaagtaatt agcataggag aagctttaat agactttata ccgaatcaaa
     5641 atggtggtaa attaaaaaat gtatcagaat ttagaagagt agcaggagga gctccagcaa
     5701 atgttagtgc tgttgtagca aagcttggag gaaaatcaag ttttatatct aagttaggaa
     5761 aagatgcatt tggtgattat ataatagatg tattaaatga agcaaatgta aatactgatt
     5821 atgtattgag aacaagtaaa gcaaatacag gacttgcttt tgtatcatta aaagaagatg
     5881 gtaatcgtga tttctcattt tatagaaatc caagtgcaga tatgctttta gaagctgatg
     5941 aagttaaaaa agagtggttt aataattgtc atatcctaca tttttgttca gtagatttaa
     6001 tagatagtcc aatgaaatta gcacataaaa aagcaataga atacgcactt gaaagtaata
     6061 gtataataag ctttgaccct aatataagat tacctttatg ggatagtgag caatcttgta
     6121 aaaaggcaat atcagaattt ttaccttttg ctcatattgt taagatatct gatgaagaat
     6181 tagaatttat aacaggagaa aatgatatag aaaaatcatt acataaactc tttgtgggga
     6241 atgttgaact agtattatat acaaaaggaa aagatggagt agatgcatac actaaaaaag
     6301 taaaaggtat gtgtaaaggg gttaaagtaa atgcaataga tacaaccgga gcaggagatt
     6361 cttatatagg ttcattttta tacaccttat tgtataaaca aataacattg aatgatataa
     6421 aagaaatgaa acaagaaacg ttaaatgagt atttagaatt ttctaattat tatgcagctc
     6481 gtagtacaac tattaaaggt gcgataagtt catatgcaac aaaggaagaa ataactgaat
     6541 ttataaaaaa tttatagtag gaatgagtaa taggttttga agtaagtaac atgtaaagag
     6601 tttttaagga tgtttactat gaaaataatt aacatataaa aagcaataag gaggctgtct
     6661 caaaatagag ataagcctct ttatcattgt tgaaatgata aaaaatattt taattattgt
     6721 tactttttag aagaatatat atcttatttt aaataagcaa attatgtaag atttatttat
     6781 attatcaata ctttacttgg agtattatgt ctttagcagt tatctaattc aattgaatta
     6841 gataaaatat aataaatttg ttttgcaaat tgacgagaat gttcttcttt ttctttattc
     6901 ataaaattag gtttacctaa atcacgttca acaagcattc ctatatattt taactgtgaa
     6961 tgcttacagt agcgcttcat accattttcc caaatatcag cacccttttc aggtctatat
     7021 ccacatgttg taataagtgc tactggtttt cctgcccata gagcggggcc tttctcatta
     7081 ccatagtatt tattcattcc atacaccaat ctgtcaagta gtgctttcat tggagaagtg
     7141 cagtaccaag aataaattgg agtagcaaaa acaattaaat cacacataag aattttcttg
     7201 aaaattttct gaacatcatc tttacaataa catccaaaat caaataagtt atcctgacac
     7261 tttttacaag caatacatgg ctctatttta caatcatata accatattac ttcaatattt
     7321 gaattataat tttctaattc ctcaataaaa ggttttaaaa tagcagcagt attacctttt
     7381 ttcttaggac ttcccataag aatgcatact tccatattga tacctccaca gtattttaaa
     7441 atagttttta gtgcttaata tagttttagg atactatgag aatacgttaa caacaataca
     7501 ctttgtatat ttgtaataaa attgaaacaa attgttttat caataaaagt tggaatgtat
     7561 ctataattaa aaatatttta ggtatgtttt tacatatatg tgtgtagtta actatggtaa
     7621 tttattgtaa aattatctta taggattata attgcttaat ttatgattat atttaaaatc
     7681 ttggaggtaa aaaatatgta ctcaaatgaa gactataaat ttatagaaga aaatgcacca
     7741 tgttatatat atgatgagac taatataatt gaaaaatgta aggaattgaa aaataatatt
     7801 ttaggttttg attttttata ttctataaaa acaaatccat ataacaaaat tgtaaaaagc
     7861 attgcagagc aaggttttgg agcagatgct tcttcaacta atgaagttat gatttcatca
     7921 gaatgtggag tttctaaaga tgatatttat tattcatcac caggcaaaac agagattgat
     7981 atagaaactg ttttagataa atgcataatt attgcagata gtattacaga aatagaactt
     8041 ataaataaga tatctaaaaa gcataatcag aaagttaaaa taggaataag aataaatcct
     8101 gattttacta tggatgatga cagtgctaaa tcaagcaaat ttggtataga tatagaagat
     8161 atgagcagtg tttttaagat gttaagtatg tgtgattatg tatctgtagt tgggattcat
     8221 atacatatta aatctcaggt attggatttt gaaaagttag gacattatta tgaaaaatgt
     8281 ttttttatag ctttaaattt aaataaaagt aagtatatta atattgaatt tataaatttt
     8341 ggtagtggac ttggagtagc ttatgataat cttagagaaa atccacttaa tcttaaagag
     8401 ctttcaaaat taactcaaaa gattgctttt actaattcaa acacactaaa atcaagactt
     8461 cttattgaat caggacgttt catagtttgt aaatcaggta attattatgt taaaattgta
     8521 gatattaaag tatcaagagg gaaaaaatat cttattgtaa aaaatggact taatggattt
     8581 atgagaccta ttatttctaa tttaattgaa aatattactt gtggagtaga attagaaggt
     8641 caagagccat tatatacatc aaatcatgcc ttttctcttt cagtattaaa taatttaaaa
     8701 gaagaagagt atgtaaatgt tgttgggaat ctctgtacat cattagatgt aattgcaaat
     8761 aatgttaaat tgaaaaaagc aaacatagga gatttgattt caattagtaa tgctggaagt
     8821 tactcctatt ctttatcacc gctattattt tcaagttatg aatttcctaa acaatattat
     8881 aaaagaaaag atggatatat tgagtaaaca atagcataaa ttaataaact tagtattatt
     8941 gaaaaaattt aaaatgcagg gggtgtaatt ctatatggaa ttgtggaaaa gaaatttatt
     9001 tgtatgttgg ataggtatgt tttttagttc tatagggatg agccaaatag cacctatact
     9061 tccattatat attaaacagt tgggggtaac tgatgttagt ttaatacaac agtattcagg
     9121 tataattttt ggatgtacct ttgtagtagc agcattcttt tcgccaattt gagggaaagc
     9181 tgctgataaa tatggaagaa aatcaatgct tttacgtgca agtattggga tgggaatagt
     9241 tatatttacc atggcgtttg ttcaaaatgt ctatcagtta ttaggattaa gaatacttca
     9301 aggagttttt acgggttatg ctactgcatg tactactctt attgcaacac agacagataa
     9361 aaatcattca ggatgggctt tgggtactct tgcaactgca tcaactactg gctcattaat
     9421 tggtccaaca gtaggaggat atatagaatc aatcttaggt cttaaaagta catttattat
     9481 aacaggagga ttgttgtttg tatcatttat catctctatt ttatttgtag tagataattt
     9541 taaacctaaa gaaataaaag aatcaatttc tatacctaaa gaacaattaa atatattgcc
     9601 aaataaattt ttaattgcat ctatttttgt aaccacattc attactcaac tagctttata
     9661 ctctatagaa ccaattgtaa ccatatatat atcacaactt acaaattttg catcaaatgt
     9721 agctttaata gctggattga cattttctgc atcaggatta gcaaatttat tagcagctca
     9781 aaaacttgga aaaatgtcgg ataaaatagg tcctcaaaaa gtattgttaa tttcactttt
     9841 atgggctggg attatattta taccacaagc ttttgtaaaa actgcatggc aactgatgtt
     9901 gttgagattt ttattagggt tgtcagttgc agggcttaat ccttctgtta acagcttact
     9961 taaaaaaatt gcaccagaag aatatgtggg aaaaatattt ggatataatg catctgccca
    10021 gtatataggc tgttcatcag gagcattttt agggggacaa atatcagcac atttaggtat
    10081 tagaacagta tttttttcaa caagtttatt gttgtttatg aatgcacttt ggatgtataa
    10141 atttactgga ttgtttatta aagataagac taaataatca tactatttac atttctaatt
    10201 ttatgatgta aaataaatat tttttatgta atttatcata gaattatata aaaaataacc
    10261 ctatggtaaa aattggaaaa tattattatc gacaaaatct ttgacttaaa aactatattg
    10321 cgatagtatt aatttaataa aagtttgaga ggggcgtaag gttatgacaa tttcaaaaat
    10381 accacaagca gaattaaaag ttatgaagtt tatttgggaa aaaaatgata cagtaacatc
    10441 aaaagaaact attgaagcta tggaacgaaa atatggttgg aaacaaacaa ctacattgac
    10501 acttttatca agacttgtta aaaaacattt tttaagtgca gaaaaaatag atagatacac
    10561 tcattataca atagttgttg gacataagga gtatttaagt gttgagacaa aagatttttt
    10621 aagcaatata cacgacaatt ctttacagag tttaatttca gcactacatg atgatgaagt
    10681 tgttgataaa gatatgttgg atttatttga aagtcatttt aaaaatttag aagaagagta
    10741 attatatcag gatagaactc taagaattta attaatctat ggctgaaaac cataaatggt
    10801 attatttaat cagctactca ctattcataa agtaatatta aataggttct ctaattagta
    10861 aaatgcctaa aataattgga atagggagta tcaagttaaa tgataccact tatttaaata
    10921 agaaatgatt tttaaaattt aaaataattt tataacttgt caatattcat taatctaaag
    10981 tattatttct atttaaccat atcaaaatat attttactat ttttaattat tacaatataa
    11041 acctgtcttt tgttattata ggtaaactaa aagtaagaaa tgatttttat atttttaaac
    11101 tttattattg gtaacttatc tgtaaatatt ttaaaatgta ctatagaaag ttgttaaaaa
    11161 tattaaataa ttatattaaa tttaagtgtg ttttttatgc tataattagt atgtattttt
    11221 tatgatatat tttataaaaa atataattta atcatttttg aggatattat tatgttagat
    11281 gcatttataa caattgtttc ttctattata gaaatatggt catgtaaaaa agtttttgat
    11341 tatactagtc agtcaaagac cgacttaaaa aaactaaata tgtattttct cttttctgtt
    11401 tttcttatta tttcttcttt atatataaat ataggagcta atagtagaat cttgatatgt
    11461 atatttgtaa tgttcgtttt ctataagtct aactataagg ttaatatata taaatgtctg
    11521 gtaatctcat ttttttattg gttaatatta ataggtataa atggattaag tatgttatta
    11581 gtagcaacag taagcaattt ggataatatg aatgttttac ttagtggcag tttatataga
    11641 tatgaagcaa tattcttggg aaagataatg ttaggtatat tactttatgt ttataaggct
    11701 tcttttaaaa attttaaaat aagtaaaaaa gagatataca tatgtattcc tatgatagca
    11761 aatttattgt cattttttgt actttatgat tatattatta atcttgtaaa aatctctcct
    11821 gaaagaagaa ctgctttttt agtaatagtt ttactattaa tattatctaa catttcaatc
    11881 tttgtattaa tacatataat acttaagatt aaaattagga aaataagata aattttaaca
    11941 cgattcattt aaattaaaag ttaataatta cttttttatg tataatttta catgaatttc
    12001 tataaaagtt attttattaa agatagatat acttatatat acggatatga ttaaaaaaag
    12061 tctttttaac tttaaaaatt aatgttaaaa aataaactta tacattaata ttaataataa
    12121 ttatttaaat atcttaagta aatcagtctt acatatattt ccgatagatt atattgataa
    12181 aaaacactaa aattaaatta ataaaagtac ttggagggat ggaaatgaaa gaggaaaatt
    12241 ttattaatgt tgaatacgag gataaacgtt tttcaattaa tagtaaagaa gttttgtaca
    12301 tagaaaagca agagtatgaa gtaaagattt atactgaaag tggtaattat gaagttggag
    12361 aaaatgctcc ttgtataaga aaactattga aagaagaaaa ttttttcaaa tgcagtaata
    12421 gttatattgt aaatctagac aagtgtgaat tttatctcag caataattgt atttttgtga
    12481 ataataattt tataagaatt ttaggttcag aaagaaaaaa gaaattaaaa aagaaattag
    12541 aaaaattata tgattatgaa gattaatatt gagaggctgt attttataca gcctctttat
    12601 ttattgattg tattattaat aaattttaaa ttatgataaa atataaaaca agtaacttat
    12661 ttcagaataa aatacttttt aaaagaaagg gacgagatat gggagattat aataaaatgc
    12721 ttgaattaaa gaataactta ggtatcagtg aaagaaagtt aaaatatcct tgtatctata
    12781 aacatttcaa agggaaatat tatgctacaa tgggtcttag caaggctatt gatgatatag
    12841 aaaacatatg tgaaatatat ggtaaagaaa atttaatcca aaacagaaat aaatataaat
    12901 tagttattag acatactgaa agagaagaag atatctatgt ttatagggat ttagatggaa
    12961 acttttatca taaaaaagaa gaagatacta atgatttagt tttatacaag accttatatg
    13021 atgatacagg aatatttgca agacctttgg atatgttttt agaaaaagta gatacagata
    13081 agtatgtcaa ttcaattcaa gaatacagat ttgaagaagt atataaataa tataagagaa
    13141 atatgtttat aaatttagaa aaattcttta acagtacaat aatttgcaga aatacaaatg
    13201 agatttattg taaataatat gttagattag attataaaat agaaacaaag taaagtatta
    13261 tatgatataa ttaagttttg agaagtgata atttatattt aataaaaaat aggcatatat
    13321 taggaggaca tatgggaaat actttttata tagtaagaca tggacaaacg gattggaata
    13381 tattgggaaa aacacaaggt catggtaatt ctgaccttac gcctcaaggt atagaacagg
    13441 caaaagaact ttctgaagat attggcaagt attcaattga ttatattttt agtagcgacc
    13501 ttgggagagc aatgcaaaca gctcaaattt taggagataa gctcaatatt gaagttcaaa
    13561 aaactgaggc acttagagaa atgggattcg gagtttggga aggcctttta ataaaagaaa
    13621 ttcaaaaaga ttattcagat atatatgcaa catggagaaa tgaaccacac ttagtaaata
    13681 taccagaagg cgaaactctt aagattataa aggagagagt agatgctttt ataaaggaac
    13741 taaatgaaaa atacgataat aaaaatataa ttcttgttac acattcaatt acattgaggg
    13801 ttatgttgtt gtcattttta gaatcaggta tggaaaatat atatagaatt aagcaagata
    13861 atactgcttt aaatatagta gaatttaaag attatggacc tgttatagta aaaatgaatg
    13921 atacaagtca tataaaaaat catgtaaaga taaataattc tgcactggag taggaatcaa
    13981 ttataaggag aaatttatga gtaaagttat agtagttggt ggaggagctt ctggaatgat
    14041 ggcagctttg tcagcttcaa aaaacaataa tgaagtaata ttagttgaga gaaatggaga
    14101 attaggaaga aaacttaggg caactggtgg cggtagatgc aattttacca ataatagaga
    14161 gatagaagat ttttttgata aagttgtcag taataaaaaa tttctctata gtagtttcta
    14221 tacatttaca aataaagacc ttatttcgta ttttgaaagt agaaatttgg aatataagat
    14281 tgaagaagaa aatgaccaca aagtatacac taaaaatgat aaatctatag aagtaataga
    14341 agtattaaat aaagatttac tcaatcacaa tgtaaagata atgtataata agaaagttat
    14401 agatattata actgaagaaa ttgctctaaa agatgattct aataaggaca agtcaaagta
    14461 tctaataaaa gggattattt tagataatgg agataaaata ctaggagaca aggttattat
    14521 atcaactgga ggagtgagtt attcaaagac gggttcagat ggttcaatgt ataagattct
    14581 taaaaagcat ggacatacat taaacaaact atatcctgct ttagttccac ttacaataga
    14641 ggaaaaatgg attaaagatt tacaaggaat atccatgaag aatgtggaaa tatcttgtaa
    14701 gattaagaaa aggaaaatat caaaatctgg agacatgcta tttgcccatt ttgggataac
    14761 aggaccttgt gttcttataa tgtcttctta tattaacaag attattgaaa aggaaaaggt
    14821 agaattaaat atagatttct taccaaattt aagtactgat gaaatctcta gtataatcag
    14881 agcatttcca aataaaaatg ttctaaataa tcttaagcaa atactacctc aaaatttctt
    14941 aaaagagatt ttttctctat tatctttagt tgataaaaag gcaagtgatt tgtctaaggc
    15001 agatgaaatt agaattattg agtatataaa aaatatgaag ctaacttgta atgggactac
    15061 aggtataaac actggtatgg ttacttctgg tggtatttca gttaaagaaa ttaattcttc
    15121 tactatggaa tctaaattag ttaagaactt attttttaca ggtgaagtaa ttgatataga
    15181 tgcagaaact ggtggatata atttacaaat agcattttca actggatatc ttgcgggtat
    15241 aagtgtataa atataatttt ttaataatta aatatgaata aatagaggtg tatatatggg
    15301 taatttagtt atagctgtag atggtccagc aggagctgga aaaagtacaa tagccaagat
    15361 agtagcaaaa aagctaaata taaattatat agatacaggt gctatgtaca gagcagttac
    15421 ttataagtgt ttaaaaagtg gtattgatgt caataatgca aaagaagtta ttcaaacagc
    15481 tgaaaattcg gatatagatt ttaaagataa caatatatat ttggacaaag aagttataaa
    15541 tgaagaaata agaacaatag aagtaagcaa taatgtttct aatgtagcaa aaataaaaga
    15601 agtaagacag ttgatggttg aagttcaacg aaaaatagga atgaaaagtt cagtaatact
    15661 agatggtaga gatataggtt catatgtttt cccagatgca gattacaaat tctttttagt
    15721 agctactcca gaagaaagag gaaatagacg ctataaagaa ctttgtaata aaggatataa
    15781 tactacttta gaagaagtaa ttgaggatat aataagacga gatgaaattg attcaaatag
    15841 agaatttgca ccattggtaa aagctaatga tgcactagaa atagatacta caggaaaaac
    15901 tatagaagaa gttgtagaag aagttgtatc taaaataaat ctttagtttt ttatgcatca
    15961 taatgaaaat aaatgtagtg ttgaagggag ataaacgtga atttttatag atttgtaata
    16021 aatattttta agggtttttc taaaatattt tttaaatatg aagttatagg tgcagaaaat
    16081 attccagata gagggaatat agtaatagca tcaaatcata aatcgaatct tgaccctata
    16141 ttcttggctg ctgccataga aaatagagaa atagctgcaa ttgcaaagaa agaattgttt
    16201 aaagtaaaac cattgggatt tatattaaaa aaattgcatg ttatgcctat aaatagagaa
    16261 aaaccagatg tatctacaat aaaaactatt ttaaggtcag ttagagatgg ttatgtatta
    16321 ggaatatttc cagagggtac tagaataaaa ggagattctt ttggtaaggc taaggcaggt
    16381 ctttctgtat ttacaataaa aagtaaatct aaagttgttc cagtatcaat aatatctaaa
    16441 tataaacttt ttagtaaagt aattgtatat attggagaac caatatcatt tgaagaacat
    16501 tttaaggaaa aattgagtaa tgatgaccat gaaaggatat cacaagagat tttagaagtg
    16561 ataaaacaaa attactttaa atattcaaaa taagggggta aagttatgaa cataaaaata
    16621 gcaaaaaatg ctggcttttg ttttggagta aaaagagcaa tgaaaatggc atgggatgaa
    16681 gttgaaaaaa atgattctgg catatatgct ttaggtcctc ttattcataa caagcaagca
    16741 gtagcaaaat atgaagaaaa aggtcttaag actgtgaatg aaattgatac aataccaaat
    16801 catgaaaata tgataataag gtctcatgga gttcctgaaa atatatataa ggaagccaaa
    16861 gataaaaaat taaaaattgt ggatactaca tgtccatttg taaagaaaat acatacagta
    16921 gtaagtgaat atcataataa aggctatgaa ataatagtta ttggagatat gaagcatcca
    16981 gaagttatag gtataaatgg atggtgtgaa aattcagcta taataataaa gaccttagaa
    17041 caaatggaaa atatggaatt tgataactcc aaaagatatt gtcttgttgc acagactaca
    17101 ataaatccag agttgtatat aagtatagtt aataaactat cagataaatt agaagaaata
    17161 gtatttaatg atacaatttg ttcagctaca aaaacaagac aagaatcagc taaagagtta
    17221 gctaaagaag ttgattgtat gatagttata ggaggtaaac acagttcaaa tactcaaaag
    17281 ttagtaaagg tttgtgaaga cttagtacca acttttgcaa tagagactaa agatgaattg
    17341 gatgtaaata cgcttaaaaa atataaaaat ttgggtatta cagcaggggc atctacacct
    17401 aattggataa tagaagaagt tgtaacattc cttgaaaatt tataatttga taggtaataa
    17461 aaataggtgg acattgttat aatttatcat aatatccacc tttgatttca tattacatgt
    17521 ggtaaataga taacctaata tcaaaaagtg tgtatcttaa gatgaaaaac taatagtata
    17581 agatgcgcac tttttaatat tagaaattca aaagaaatgt tgatattgat tatcaataga
    17641 aaataaaata taatataatt gttgcaaaat tagtctagga ggtaaattaa tggaaatgtt
    17701 gatatccgct tctgaagagg cgtttttaca tgtaggttct atgattggat tttttatttt
    17761 gttatttgga tatattaatt ataaaactag tggaaatttt actaatatca tatcaaaaaa
    17821 cagaaaattt caacccttaa taggtgcttt aattggagct ataccaggtt gtggcggaag
    17881 tttggcaata atgccattgt atataaatgg aaaattaagc tttggagcaa taattgcaag
    17941 tttaatagct agtatgggag atgcagcatt tgtacttatt tcatcaaata ttaaaatgta
    18001 tttttttgtc actatagtta gtacaattac aggaataata actggacaat tagtggatta
    18061 ctttaaacta gaagaaaaat tagggttaaa aaaccgtaga aaatcagata gatatgatat
    18121 aagtaaaaat aaccctaaag aaaataaaga acaacataat catgatgaaa taattttaga
    18181 cactctagct aaatctcatg gaaatacaaa tagacttgca tttataataa cacatggaaa
    18241 gggatataaa atttatatag gaattatagt aatcggtttt atatttatgt cacttgctca
    18301 ctctggactt aatcttccta taattgagaa gttacattca ttggaagaag taatagcagt
    18361 gattggaata ttattttcaa taatttatat gtggtgtttt aaaaaggtat ttaaaaattc
    18421 taatcaaaaa gaggaagaaa ataaaaagat ttctttgcga gaaatgctta tccattctgt
    18481 tggagaaata tcatttgtaa ttacatggat ttttattgca tatcttattt acgatttgat
    18541 aatattaatt ttaggtggag atgaatactt agttaaatta gtattatcaa caggtgtaat
    18601 aagtgtattt ataggtgcag gtcttggact tattccaggt tgtgggatac aaattgtgct
    18661 tatgtcattt tatttgaagg gaactatacc acttggtgca gtgatagcca actctatttc
    18721 tcaagatgga gatgcacttt tcccactttt agcaatggat aaaaaatctt ctttatgggc
    18781 tatgattatt actactatac cagcaatact tgtaggtatg atagtttatg catttttagg
    18841 ttaaatataa ttatgaataa agaagtatta aaaaaataat aaagcacata aatttattta
    18901 taagaatagt gaagattaaa tataaaaata aaaaattcaa tatgaattaa attattgctt
    18961 aaatattaat gagaacatgg gagataatat tattcctcat gttctctcta tttaattaaa
    19021 ggaattatgg aacaaatttc aagtgatact ttctatcaaa actcatatat aatatatatt
    19081 aataaattaa actataatac gtaatacagc cagtatattg atataaaaaa cttaggagga
    19141 gttgtaaaaa tgggtaattt aaaaagacag tgtgatgttt caagtggaag agaaaaagct
    19201 gacattgtac taaaaaatgg gacaatcata aatgtattta cagaagagtt aataacagga
    19261 gatgtagcaa tagtaggaga cactatcgtt ggcattggcg attacaaggg caatgtagaa
    19321 attgattgta gcaataaata tatatcacct ggctttattg atgcacatat gcatattgaa
    19381 tctacaatgg taatgccaat tgaattatcg aaaaaattat taaaatcagg tacgacaact
    19441 atcatagccg acccacatga gttggtcaat gtaaaaggag ctagtgcaat agatttttta
    19501 ttagaatcga caaaagatat accacttaat gtatatatta tggtgccttc atccgtacct
    19561 gcaacaagtt ttgaaactaa tggagttggt aaatttagtg caaaagacat ggagagttat
    19621 gtaaataatc ctagaatttt aggtttagga gaggtaatgt gttttaatga tgttataaat
    19681 tctgaaaatg aaatcttgga taaactagag ctttttaaaa ataaagttgt agatggacat
    19741 gcacctaata taaatggtaa atcacttcag acatatgtat gtgcaggaat agaaaatgac
    19801 catgaatgta taacttttga tgaagtatat gaaaaattga gagcaggatt aaaaatttta
    19861 ataagagaag gaagcgcagc aaaaaattta aagtctatag taagtggtat gctaaagcat
    19921 aacttgccaa ttgaagaatt tatgttttgc acagatgata agcacttaga tgatatagaa
    19981 aaacaaggtc acataagatg gaatataaaa tgtgcgattg atttaggtat ggaacctgtt
    20041 agggctataa aagttgcaac ttataattct gcaaaagcat atgggttaag gaaaattgga
    20101 gcaataggtg cgggttataa ggcagatatt gttgtattga atgatttaga caaaatggaa
    20161 gtggatagtg tatataaaga tggtaatttg gtaaacgaag agatgttttc taattacaat
    20221 tatgagatta aagataaaga attgcttaat acagtcaagt ttaaatatat taataaagaa
    20281 aaaatacagt taaaagtaag tgaaaaaaat tatgtaatgg agattgtacc ttatcaaatt
    20341 ttgacaaata agttatatga atctttacca tgtgcagatg gatattttgt tccaaataaa
    20401 gagtattcaa aactttgtgt tgttgagaga catagaatga ctggaaatgt agcaattgct
    20461 ccactaaaag gatttggcat aaaaaatgga gcaattgcta ctactgtggc ccatgattct
    20521 cataatatta tagttgcagg ggataatgat gatgatattc tagtagctat aaattactta
    20581 aaggaaatac aaggtggtta tgtaattgta tcaaatggaa aagttcttgc acacctaagt
    20641 cttcaagtag ctggattaat tagtactttt acagctgaag aagtacaaga aattactgat
    20701 aatatgttgg agatagcaag aaaaatggaa gttccagagt atgtagaccc ttttattaca
    20761 ctttctttta tggcacttcc agttgttcca caaataagac ttacagattt aggtctattt
    20821 gatgttgagg aatttaaatt tatatagata gtataaaagt aataataaat gaggctttct
    20881 caaaatagag ataagtctct ttttattgtt gaaatgatga aaatatattt gatttcatac
    20941 aaaaaagagc atctcatgaa ctaaaaattt tatttttaga tatccttatt ttaattaatc
    21001 tatcatttaa cattgtttta agcatagata tcttaataaa actattttca gtctatttta
    21061 acatataaat acatgaaaat tatatattta tgaaacttta tacataaaaa ataaaatatt
//
LOCUS       DAEPUT010000069        21037 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.071, whole genome shotgun sequence.
ACCESSION   DAEPUT010000069 DAEPUT010000000
VERSION     DAEPUT010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21037
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.071"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            27..101
                     /locus_tag="KRL22_002777"
     tRNA            27..101
                     /locus_tag="KRL22_002777"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="KRL22_002778"
     tRNA            116..200
                     /locus_tag="KRL22_002778"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="KRL22_002779"
     tRNA            210..293
                     /locus_tag="KRL22_002779"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="KRL22_002780"
     tRNA            317..391
                     /locus_tag="KRL22_002780"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="KRL22_002781"
     tRNA            416..492
                     /locus_tag="KRL22_002781"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            500..575
                     /locus_tag="KRL22_002782"
     tRNA            500..575
                     /locus_tag="KRL22_002782"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:533..535,aa:Gln,seq:ttg)
     gene            584..659
                     /locus_tag="KRL22_002783"
     tRNA            584..659
                     /locus_tag="KRL22_002783"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:617..619,aa:Lys,seq:ttt)
     gene            662..750
                     /locus_tag="KRL22_002784"
     tRNA            662..750
                     /locus_tag="KRL22_002784"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Ser,seq:tga)
     gene            754..829
                     /locus_tag="KRL22_002785"
     tRNA            754..829
                     /locus_tag="KRL22_002785"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:787..789,aa:Phe,seq:gaa)
     gene            836..909
                     /locus_tag="KRL22_002786"
     tRNA            836..909
                     /locus_tag="KRL22_002786"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:870..872,aa:Met,seq:cat)
     gene            924..1000
                     /locus_tag="KRL22_002787"
     tRNA            924..1000
                     /locus_tag="KRL22_002787"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:958..960,aa:Ile,seq:cat)
     gene            1018..1094
                     /locus_tag="KRL22_002788"
     tRNA            1018..1094
                     /locus_tag="KRL22_002788"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1052..1054,aa:His,seq:gtg)
     gene            1103..1178
                     /locus_tag="KRL22_002789"
     tRNA            1103..1178
                     /locus_tag="KRL22_002789"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1136..1138,aa:Lys,seq:ttt)
     gene            1186..1259
                     /locus_tag="KRL22_002790"
     tRNA            1186..1259
                     /locus_tag="KRL22_002790"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1218..1220,aa:Cys,seq:gca)
     gene            1267..1343
                     /locus_tag="KRL22_002791"
     tRNA            1267..1343
                     /locus_tag="KRL22_002791"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1301..1303,aa:Arg,seq:acg)
     gene            1356..1431
                     /locus_tag="KRL22_002792"
     tRNA            1356..1431
                     /locus_tag="KRL22_002792"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1389..1391,aa:Val,seq:tac)
     gene            1507..1920
                     /locus_tag="KRL22_002793"
     CDS             1507..1920
                     /locus_tag="KRL22_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273246.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVYGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2229..5660
                     /locus_tag="KRL22_002794"
     CDS             2229..5660
                     /locus_tag="KRL22_002794"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBH1273247.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5902..7830
                     /locus_tag="KRL22_002795"
     CDS             5902..7830
                     /locus_tag="KRL22_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH1273248.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            8283..8747
                     /locus_tag="KRL22_002796"
     CDS             8283..8747
                     /locus_tag="KRL22_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBH1273249.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8754..9248
                     /locus_tag="KRL22_002797"
     CDS             8754..9248
                     /locus_tag="KRL22_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HBH1273250.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            9264..10289
                     /locus_tag="KRL22_002798"
     CDS             9264..10289
                     /locus_tag="KRL22_002798"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HBH1273251.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            10276..12723
                     /locus_tag="KRL22_002799"
     CDS             10276..12723
                     /locus_tag="KRL22_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBH1273252.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12903..14276
                     /gene="radA"
                     /locus_tag="KRL22_002800"
     CDS             12903..14276
                     /gene="radA"
                     /locus_tag="KRL22_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBH1273253.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            14279..15349
                     /gene="disA"
                     /locus_tag="KRL22_002801"
     CDS             14279..15349
                     /gene="disA"
                     /locus_tag="KRL22_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HBH1273254.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15438..16532
                     /locus_tag="KRL22_002802"
     CDS             15438..16532
                     /locus_tag="KRL22_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBH1273255.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16661..18838
                     /locus_tag="KRL22_002803"
     CDS             16661..18838
                     /locus_tag="KRL22_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273256.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(19024..19794)
                     /locus_tag="KRL22_002804"
                     /pseudo
     CDS             complement(19024..19794)
                     /locus_tag="KRL22_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(19912..21030)
                     /locus_tag="KRL22_002805"
     CDS             complement(19912..21030)
                     /locus_tag="KRL22_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1273257.1"
                     /translation="MIVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNDKETFTYKQCSSDLTNLKKELNWLKEPDKFSLQNALKDLDNAYKKFFKKKAGFPKF
                     KSKKINRFSYKTNFTNGNIVYCGQHIKLPKLGMVKIRDKQVPKGRILNATISKEPSGR
                     YYVSLCCTDVDIEAFENTNNHIGLDLGIKEFCISSCGEFIENPKYLKKSLNKFAKLQR
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRKDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRYINASINILKEGLRLITIQNK"
BASE COUNT         8396 a         2429 c         3846 g         6366 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atataaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatatt ggggattagc caagtcggta aggcacatga ctttgactca
      541 tgtatgcgta ggttcgagtc ctgcatcccc agccaaacag tatggtctat tagctcagtc
      601 ggtagagcac ctgactttta atcagggtgt cccgcgttcg agtcgcggat agatcaccaa
      661 tggagaggtg tccgagtggt ttaaggagct ggtcttgaaa accagtgact tcgaaagggg
      721 ccgtgggttc gaatcccacc ctctccgcca aatgcccaga tagctcagtc ggtagagcag
      781 gggactgaaa atccccgtgt cggtggttcg attccgcctc tgggcaccaa aatgtggcgg
      841 tatagcttag ttggctagag cgttcggttc atacccgaaa ggtcataggt tcgactccta
      901 ttaccgctac taaaatttaa tgtgggccat tagctcagtt ggttagagcg cccggctcat
      961 aaccggtagg tctggggttc gagtccctga tggcccacca cattaaatta acttatggtg
     1021 ggtatagctc agttggttag agcgccagat tgtggctctg gaggtcgtga gttcgactct
     1081 cattatccac cccaacttat atggtctatt agctcagtcg gtagagcacc tgacttttaa
     1141 tcagggtgtc ccgcgttcga gtcgcggata gatcaccaaa aaggcggcga catagccaag
     1201 tggtaaggca gtggactgca actccttgat ccccagttcg aatctgggtg tcgcctccaa
     1261 taaaatgcgc tcatagctca actggataga gtgtctgact acgaatcaga aggttagggg
     1321 ttcgagtccc tttgggcgca ccatatgaat agcgagggat tatagctcag ctgggagagc
     1381 acctgcctta caagcagggg gtcacaggtt cgagccctgt taatcccacc agtgcaaacc
     1441 tctagtaaaa ctactagagg ttttattttt gattgaaaaa atttttatat ttaggaggta
     1501 aaaaatttgt atatagtaat aggaaatgaa atagttgata gtgaagaact taaaataatt
     1561 atagataaaa atagtgaatt taaagttgaa aaagatttaa gtaaaagcac aaaaagagaa
     1621 gatgtaatag catatcagtt aagtatagat ttaaattacc tagattctct tataaatgag
     1681 caatgtaatt tagccagtct atctgatgaa gagaaatttg atgaatatat gactttgtct
     1741 gatgaacttg cactggattt agaagagtta atgccaaaat atacaataat aaatgctaga
     1801 gcatataaat tagacgaggt atatggaatt gtaaaaataa tactagctgt agcgtatgca
     1861 gatttagggc acttaaaact ttctgatgta gtaaagaggc tatctagaca agtagattag
     1921 gatatgaata tgaactatat taaaaaaatg tataaaatct tacgtaaaga tgaaaataat
     1981 tatgtaaaca tagaaaaaaa cagtataaaa tcaagtcaat tgtagaaatt ttcacataaa
     2041 ttcatctgaa attctataaa aaatgcctta attttaatga ggtaaatcga gtttacacag
     2101 tctaaaaatt acttatattt ataaatttat cttattaatt aaggaacttt cttaaacatc
     2161 ttcaaaaata aagtatttta gtctataatc tttaatatta cacaaacaat aaaggagaag
     2221 aatagagtat gcttaaaaag tttaataaaa tactagtggc taatagaggc gaaatagcta
     2281 taagaatatt tagagcctgt tcagaattgg ggataaaaag tgttggtata tacagtaagg
     2341 aagataagta tggattgttt agaacaaaag cggatgaatc atatttgata ggagaaggta
     2401 aagggccaat agatgcatat ttagatatgg atggaataat agacctagca aagagaaaaa
     2461 aagttgatgc tatacatcca ggatatggtt ttctagcgga gaatgcagaa tttgctcgta
     2521 aatgtgaaga gaatggaatt acttttatag gaccatcatc taaggtaatg aatatgatgg
     2581 gggataagat taactctaaa aaaatcgcaa aagaagttaa tgttcaaact ataccaggag
     2641 tagaaaaagc aataagaagt actgaagaag caaaggaagt tgcaaacaaa ataggatatc
     2701 ctgttatgat aaaagcatct aatggcggtg gcggtagagg tatgagaatt gtacatcgcg
     2761 aagaagactt agagcttgaa tatgaaactg cttgtagtga atcaagaaaa gcttttggag
     2821 aagatattat atttatagaa aaatatatag ctgatccaaa acatatagaa gttcaaatat
     2881 taggtgataa ttatggaaat atagttcact tatatgaaag agattgttca gttcaaagaa
     2941 gacatcaaaa aataatagaa tatgcaccag ctttttcgtt agatgataaa gtaagaaaag
     3001 agatatgtga agatgcagtt aagttatcaa aacatgtggg ttattctaat gcgggaacat
     3061 tagaattttt agtagatgca aatggtgggc attattttat agagatgaac acaagagtac
     3121 aggttgaaca tactgtaaca gagatggtta caggaataga tatagttcaa agtcaaatac
     3181 taatagccca aggttacagc ttagatagtg aagaaattaa tataaaatca caagatgatg
     3241 tggaaataag aggttactct atccaatgta gaataactac agaagaccct aagaataaat
     3301 tcatgcctga tacaggtaaa attcaagttt atagaactgg ttcaggattt ggtataagac
     3361 tagatggagg aaatggattt acaggggcaa acataagtcc tcattatgat agtttattgg
     3421 ttaagacaat atcttgggat agaacattcc aaggagcaat aaataaaact ataagatcta
     3481 taaaagaact tagagttaga ggtgttaaaa ctaatgtagg attcctagtt aatgttttaa
     3541 ataatcctat attctcaaat ggtaaatgta gtactaagtt tatagatgaa aatccagatt
     3601 tatttgaaat aacagaaagt aaagacagag gaacaaaatt acttcaattt ataggagatg
     3661 taattgtaaa tgataatgct tgtaaagaaa aaccattatt tgatgcatta catgacccaa
     3721 gaatggataa ggatggttca aaatcagaag gaagtaaaat acttttcgat aagttaggta
     3781 aatctgcata tatagaaaag ataaaaaatg ataagaaatt actattaaca gatacaacaa
     3841 tgagagatgc acatcaatca ttattagcaa caagaataag aacatatgac ttattaaaag
     3901 ctgctaagcc aacagaaaaa tatcaaaagg atttattctc acttgaaatg tggggaggag
     3961 ctacttatga tgttgcatat agatttttaa aagaatctcc ttggcgtaga ttacaaaagc
     4021 taagagaaga aataccaagc ataatgttcc aaatgttgct tagagcatca aatggagttg
     4081 gatataaaaa ctatccagat aatgtaatag aagaatttac aaaagaatct gctagacaag
     4141 gtatagatgt atttagaata tttgattcat taaactgggt tgaaaatatg aaaccatcta
     4201 ttaatacagc tttagaaact ggaaaaattg ttgaagcaac tatgtgttat acaggtgata
     4261 tactagataa gactaaaact aaatacaatc tagaatatta tattaaaatg gcacaagaat
     4321 tagaaagctt gggagcagat ataatagcaa taaaagatat gtcaggtctt cttaaaccat
     4381 attcagctta cacactagtt aaagagttaa agaaaaatgt aaaagcacca atacatttac
     4441 acactcatga tacaagtgga aatggtgtag caacttgttt aatggcgtca gaagctggag
     4501 tagacataat tgatgctgca ttagaatcta tggcaggact tacaagtcag ccatcactta
     4561 atgctatagt agaggcactt aagaatacag agagagatac aggaatagat ttatttggat
     4621 atgatgagtt aggaaaatat tataaggatt taagaaaagt ttataataaa tttgaaagtg
     4681 atttaactaa ttcttgtgca gaaatatata attttgaaat accaggaggc caatatacaa
     4741 acttaaaacc tcaagctgat agtttaggat tagttaatag atttgatgaa gttaaagaaa
     4801 aatataaaga agctaatgaa gttgtaggag atataataaa agtaactcca tcttcaaaag
     4861 ttgtaggaga cttagctatc tttatgacta aaaataaatt agataaagat aatataatag
     4921 aagaaggtaa aaatttatca ttcccagatt ctgttgtgga ttactgtaaa ggtatgattg
     4981 gtcaaccaga aggtggaata ccaaaagatt tacaagaggt agttctaaaa ggtgaagaag
     5041 ctataacagt aagaccaggt tcattattac cagcagaaga ttttgatgaa atagctaaat
     5101 atctaaatga aaagtatgat ataaatgcta atataagaaa tgttataagt tatgctttat
     5161 atccaaaagt atatgaagat tatatcaaac atctacaaca ttataatgat atatctaaac
     5221 ttgaaagtga tgtattcttc tatggattaa ataaaaatga agaatgtgaa gtagaaatag
     5281 aagaaggtaa ggtattaaca ataagattag ttgaaattgg tgaagttaag gaaaatggat
     5341 ttagaactat aggatttgag ttaaatggaa tggttagaga agtagaaata aaagataaga
     5401 atttctctgg aaaaattaat aatgttgaaa aagctgatat gaatgaccct cttcaaattg
     5461 gagcaagcat accaggaaaa gttataaaaa taatggttaa agaagaagat gaagtaaaag
     5521 caaatcaacc attaatcgtt atagaggcta tgaagatgga aactataata gttgctaaga
     5581 ctgatggagt aattaagtca atcaaagtaa aagaagatga tatggttgaa gataaacaat
     5641 tattaatgat aatgaagtaa tttaattaaa ataaattaaa aagcactctg aaatgtttaa
     5701 taaaaaatgt tttagagtgt ttttatttat tttaattaaa tatttgttaa aaaaaagagg
     5761 acaattacct ccagatgtag aaataaagct agtaaggaaa atgttatcta aaaattctaa
     5821 atatagtaaa tattttccat aatatttctt aggaaataac agcaaagata aaatacataa
     5881 atttaaaagg tgggtgctta tatgaaggtt tatgatagta aaatgttgag aaatgtagcg
     5941 gtattaggac atagcggatg tggaaaaaca aatctaatcg aaactatagc ttacacagca
     6001 aacactaata agatacctaa attaacagac aaggtaaata tgacttatag catgggatta
     6061 atacctatag agtataatga ttataagttt aacttattgg ataccccagg atattttgac
     6121 tttagcggag acgttgtgtc atctcttaga gcaagtgatg cagcaataat agtaatagat
     6181 gcaacagcgc ctattcaagt tggtacagag aaatcattag aactaactga gagtattcct
     6241 aagataatgt ttataaataa aatagataat gaaaaggcaa gatacaaaga tgcaatagca
     6301 atgttaagag aaaaatacaa taataagata gttcctatga taagtcctat atacaaagat
     6361 aaaaactttg taaagttaca taatgttttt gaaaacatag atgatttaga aggtgaattt
     6421 aaggaacaag ctatgagtgt taaagaagca ttaatggaac ttatagcaga aactgatgac
     6481 caaatattag ataaatattt taatggagaa gaactaacta cagaagagat acaaaaaggt
     6541 attattatag gtatacaaag aggtgatatt atacctgtaa tatgtggttc aactataaat
     6601 aatataggca caaaggaaat attagataca atatcaagtt atttagaacc tatctttaca
     6661 gaggaaagca aaccatttag gggattagta tttaaaacta tggttgaccc atttgttgga
     6721 aagatgtcat atataaaaat tactgagggt gtactttcta aggataaaga tgtttttaat
     6781 ataaataaaa atgtaaaaga aaaaatagct aatatatata cattgagaaa tagtgaatta
     6841 gtagaaatag aaaaagctaa agctggtgat atagtagtta taactaaagt taattctcta
     6901 aaaacaggag acactatatc tgcagataaa gatgcagaag ctttagaaaa gatagatttt
     6961 cctaaaccac aaatatatta tgcagtaact cctaagaata aaggtgatga agaaaaagta
     7021 gcatctgtat taaataaact agtagaagag gaccctacat tacattggta tagaaataca
     7081 gagacaaaac aagcactttt aggaggtcaa ggagaacttc atataaaaac aattaaaaat
     7141 aaaatgaaag ataagtttgg tgttgatgtt gaattgaatg accttaaagt tccttataga
     7201 gaaactataa aaggaacagc tgatgtacaa ggaaaacata aaaagcaatc aggtggtcat
     7261 ggtcaatatg gagacgtaaa aataagattt gaaagatgtg aatctgattt tgaatttaca
     7321 gaagaaatat ttggtggttc tgtaccaaaa caatatatac cagcagttga aaaaggttta
     7381 aaagactcta tgcaaaaagg tatattagca ggatatcctg ttacaaacat aaaagctacg
     7441 ctttatgatg gttcatacca tgatgtagac tcttctgaaa tggcctttaa aatggcagca
     7501 agtgcagcct ttaaaaaagg tatggaagaa gcacacccaa tactactaga acctataatg
     7561 aaacttaaga taactgttcc agaagaatat atgggagatg tcatgggtga tataaataag
     7621 agaagaggaa aaatatttgg aatggaacca gatgacaaag ggaaacaaat aatatttgca
     7681 gaagctccac aagcagagac atttaaatat gcaatagatt taagagcaat gacacaaggt
     7741 agaggatact ttgaaatgga attagagaga tatggagagg ttccatcaca gtttgcagaa
     7801 aaaataattg ggctagctac tgcaaagtaa tgaacaaaat aaatagaaaa ataattaata
     7861 tatattatta aaaatatttt tagggtttta actaggtata ggtttatgtt aggtaaactt
     7921 atacctagtt tttatacatt tttgatgaat aaaaaaatat ataatacttt cttaaatatt
     7981 ttaataaaaa gaaagtattt ttttattatt atttttacaa atgtttagta ataaagatga
     8041 gaaggtatat ttaaaatata aagtatttaa agttctgaaa tctaatcatg aagcaaaaaa
     8101 ttagcatttg gttatcaata aatataataa ataaaaactc ataattaatg aaagaataaa
     8161 ttcatatcta aatttctata aaaaatttaa atttatacaa tttagggctt taaaaattta
     8221 aataataggt gtaaaataat agtcaaagaa agtcaaaaat aaaaaggtgt gtggtgatat
     8281 taatggcaac tatgacagat ataattgaaa aatttattaa agatttgatg gaagaagata
     8341 atagcataca aattcaaaga aatgaactag caaacttgtt tagttgtgca ccatcacaaa
     8401 taaattatgt cttaacaaca agatttacaa tagatagagg atattacatt gaaagtaaaa
     8461 aaggtggcgg aggatatgtt caaatagaaa aaatacgaaa aagtaaagat gggcatatta
     8521 gagaactact aaatgaaaaa ataggaagtc agatatccta taaaaaagca aaagaattat
     8581 tagaaggttt aaaagagtcg gatttgatta acgaaagaga attaaaatta atattatatg
     8641 caatagatga taaatcattg tgtatgccaa tatatgaatt aaaagagaag gtaaggtcta
     8701 atattttaaa gaatataata ataggattat ttagtataga ggagtgataa tttatgctat
     8761 gtcaaaaatg caataagaat aaagcatctg tatattataa taagatagtc aatggagaaa
     8821 aaacagagat gtatttatgt agtgagtgtg caaaagagaa tacagaaatg aattttaact
     8881 tagatatgcc tttttcaatg atggatatat tttctaattt aggttttcaa cctaaaaaag
     8941 aacttgagga aaagctagtt tgtcctaaat gcaatacaac atatagtgag tttaagaata
     9001 atgggagatt tggatgtagt gaatgttata atgcatttag tagtcaagta aatccaatgc
     9061 ttcaaaatat acatgggcat atagaacata caggaaaagc acctaaaaaa tctttttata
     9121 agataagtgt agaaaatgag attaaagaac taaaagaaga tttagataga gctataaaaa
     9181 atgaagagta tgaattagca gctcaattta gagataaaat taaatattta aaaggttcta
     9241 ttgactaaga ttggagtgat attatgaaag agaacatagt catgaaatca agagttaggc
     9301 tagctagaaa tttaaataac tatccatttc caaataaatt agataaagaa tgtgccatgg
     9361 aaataataga aaaagtaaaa aatgcgttta ttaattctaa cttagaacaa aaagaagaat
     9421 ttgatttcta taaaattgaa gatttagacc aatctaaaaa aatgcttatg gttgaagaac
     9481 atataataag cccagattta gcagaaaatg ataaaagtgc agttatagta aaaaaagata
     9541 aaactataag tataatgata aatgaagaag accatataag gatacaaact atatgtgatg
     9601 atttaaactt agaatatgca tatagtgtag caaatgaaat agatgatttg ttagaatcaa
     9661 gtttagaata tgcctttaac acaaagctag gttatctaac atcttgtcca actaatacag
     9721 gaacaggaat gagagcttct gtaatgatgc atttaccagc attaagtcaa ctaggctata
     9781 tggatgaact ttataaaatt tcatcacaaa taggtatagc aattagaggg atatatggag
     9841 aacgaacaga agcattggga aatatatatc aaatatctaa tcaacttaca cttggaagaa
     9901 cagagtctaa tattatagaa aatgtaagtg gacttacaaa agatgcaatt tcaaaagaaa
     9961 taaaagctag agaaatattg caaaaaaaat taggtataaa actagaagat aaaatattta
    10021 gatcgatagg gacacttgaa aattcaagag taatgagtag cgcagaggca atgagccatc
    10081 tatcaaatat aaaaatggga atagaaatga actatataga taaactagat ttaagggcta
    10141 tagaacaact tatgataggt atacaaccag cgcatcagtc aataatgtat aagagtgatg
    10201 atgttgagaa tagagatata aatagagcaa catatattag agaaactttg gaaaaattaa
    10261 gaggagggat gaattgtgaa cttcaataga tttacacaaa gagctaaaaa ggcaattgat
    10321 ttagcgtttg aatctgctaa aagtctagga cacaatattg tcggaagtga acatatactt
    10381 ttaggtcttt taagagaaga agaaggtata gctgctaaag ttctaagtaa agttggattt
    10441 acagaagctt atttagaagg caaaatagtt gatatggaag gtaagggaga agaaatctca
    10501 gaagatatag tattaagtcc aagaagtaaa caaatacttg aattatcagg aatgtttgca
    10561 aataaattaa aaacaaatta tattgggact gagcatatat tattagcaat tattcaagaa
    10621 ggtgaaggaa tagctaataa gattttaaat tatgctggag taaatgatag gactttagcc
    10681 caattaacaa ttgatatgat gggtattagt gataaaaatc aatacaaagc agaaaatagt
    10741 tacacgggca accagaatca agcagaatct aaagtacttg ataagtatgg aagaaatctt
    10801 acactatatg caaaacagaa taaaatagac cctgtaatag gtagagaaaa agaaatacaa
    10861 agagtaatac aaatattaag tagaagaact aaaaacaatc cagtgttgat aggagaccca
    10921 ggtgtaggga aaacagccat agctgaaggt ctggctacaa atatagcctt aggaaatgtt
    10981 ccagaaacac taaaaaacaa aactttatac tctttagaga tgggttcatt attggctggg
    11041 gctaagtata gaggagaatt tgaagaaaga attaaagaag ttgtagatga agttgttaaa
    11101 aatggaaaca taatcttatt tatagatgag atgcacacaa taataggggc tgggtctact
    11161 ggagaaggct ctatagatgc ttcaaatata ttaaagccag ccttagcaag aggagaaata
    11221 caagttatag gtgcaactac aattgatgaa tatagaaagc atgttgaaaa agattctgct
    11281 ctagaaagaa gattccaacc agttatggta gatgaaccaa ctaaagagga ctcaataaaa
    11341 atattagaag gattaagaga taaatatgaa gctcatcata aagttaaaat aactgatgat
    11401 gctataaagg cagctgtaga attatcaact agatatatat cagacagata tctgccagat
    11461 aaagctatag acttgattga tgaagctgca tcaaaagtaa gattaaaaga aaatacacct
    11521 ccttcagaaa taaaaaaatt agaactagaa atagaaaata tagataaaga aaaagaagaa
    11581 gcagtaagat gtcaagactt tgagaaagca gccaaaataa gagatgaaca aggtctactt
    11641 aaaaaacaat tagaagatgt tagagaaaga tggaacaagt catctaaaca ttcagattta
    11701 gttgatggag aagttattgc tgaagtagtg ggcttatgga caggaatacc agttaataaa
    11761 attcttgaag aagaggctga tagacttttg agacttgagg aaatactgca caatagagtt
    11821 ataggtcaag aacaagcagt aaaatctatt tcaaaggcaa tcagaaggtc aagagcaggt
    11881 cttaaagacc ctaatagacc aattggttca tttttatttt taggtccaac aggagtaggt
    11941 aaaacagaat tatctaaggc attagcagaa gtgcaatttg gagatgaaaa tcaaataatt
    12001 agaatagata tgtctgaata tatggaaaaa catgctgtgt caagaatgat aggttcacct
    12061 ccaggttatg taggtcatga tgaaggtggt caattaactg aaaaagtaag aagaaatcca
    12121 tattcagtta tcttatttga tgagatagaa aaagctcatc cagatgtatt taatattctg
    12181 ttacaaattc tagatgatgg tagactaact gattcaaaag gaagaactgt agattttaag
    12241 aatactattg taataatgac atcaaatgtt ggagcatcta caattggtag acaaaaaact
    12301 ttaggattta gtatagctaa aggagacgaa gaagaaaaat ctcaatatga aaaaatgaaa
    12361 gaaaatataa tgggtgaatt aaaacaaaga ttcagaccag agtttttaaa cagaatagat
    12421 gatataattg ttttccactc actaaatgaa aatcatatat caaaaatagt acttttaatg
    12481 gcagcgaaac tacaagagag attaaaagaa atggatataa aattagaaat gagtgatgag
    12541 gctgttaaat taatttctaa atctggattt gacttagaat atggagcaag acctcttaaa
    12601 agagctttac aaaaagagtt ggaagatgag ctatctgaag caatcttaaa aggtaatgtg
    12661 aaaaagggaa gtaatgtagt agcaaaagtc aaagatgaaa aaatagtttt tgaaactaaa
    12721 taatttaata gagttgcatt ttaaaatatt gcaaatataa gttttataat ctaaacaaaa
    12781 ttttaagggc aatgaatcta taataattca ttgtccttaa ttattttatt taatctttac
    12841 atattgtctt tcagatatgc taaaattata gtatagaata aaaaattaag gatgataaaa
    12901 gtatggcaaa aataaaaaca aaatatgtat gtcaatcttg cggatatgaa acagctaaat
    12961 ggcttggtaa atgtccagaa tgtacaaaat ggaatacatt tgtagaagaa atagaccaaa
    13021 aaagcaccaa aaaagaggtc tttataatag ataaatcttc atctaaacca gtcagtataa
    13081 actcaataga aagtaaagaa gaagagcggt ttacaacaga tataaatgag ttagatagag
    13141 tgcttggagg aggtatagtt aaaggctctt tagtgcttgt tggtggtgac cctggtatag
    13201 gtaaatcaac acttttaatc caagtatcta gtaatgttgc caatttagga aaaactgttt
    13261 tatatataac tggagaagaa tcagaatctc aaataaaaat gagagctaaa agattaggta
    13321 ttaactcaga aaatttatat atatttgctg aaaataattt aagtataatt gaatcttatt
    13381 tagaaagtgt aaatccagaa ttaataattc tagactcaat tcaaactgtc ttcagtccag
    13441 aaatatcctc ggcaccagga actgtcagcc aaattaaaga aggtacttca aaattcatga
    13501 aaatttctaa aaaaatggga atttcaacgt tcatagttgg gcatgttaca aaagaaggtt
    13561 cactagcagg accaaaatta ttagagcata tggttgatac tgttctatat tttgaaggag
    13621 aaagatataa tacttataga ttagtaagag ctgttaaaaa tcgatttggt tcaactaatg
    13681 aacttggagt atttgaaatg agggatttag gattagtaga acttgataat ccatctaaaa
    13741 ttttaatctc tgaaaaacca aaagatgtag caggttcagt aataatatct actgtagaag
    13801 gtacgagacc aatgttactt gaattgcaag cattagtttc tcctacaagt tttggtatac
    13861 caaaaagaac atctacagga gtcgattata atagagtagg tatgttatta gcagtattag
    13921 aaaaacgtgt tggtttgcaa atacaaaatc aagatgtcta tataaacata gttggaggaa
    13981 taaagataaa tgaaccctca attgatttag ggatagccat ttctgtagca tctagtttta
    14041 gaaatatacc gatagatgaa gatatagctg ttacaggaga agtgggactt acaggagaag
    14101 ttagagcagt aagctttata gaaaagagaa tagctgagtg taaaaaactt ggatttaaaa
    14161 agatagtagt tcctagaagt aattatgatg ttgtaaaaga gaccaaaggc atagaaatat
    14221 ggccagtaga taacttaaga caagctataa atatagtact tgggaggaat caataaatat
    14281 ggagaatttt ctagataata aaaatatgct atatgcatta aaaatgatat ctcctggaac
    14341 tccacttaga ttaggtctaa acaatgtact aagagctaag actggtggat taattgtaat
    14401 tgcaacaaac gaagatgtaa tgaaaatagt agatggagga tttgctataa atgcagaata
    14461 ttcaccatca tatctatatg aattagctaa aatggatgga gctatagttt taagtggtga
    14521 tgtaaagaaa atattatttg ctaatgcaca acttatacct gactatttta tagaaacatc
    14581 agagacagga acaagacata gaacagcaga aagagtagca aaacaaactg gtgctatagt
    14641 cataggaatt tcacaaagaa gaaatgttat aacagtttat agaggaaatg agaagtatgt
    14701 agtcgaagat atatctaaga tatttactaa ggcaaatcag gctatacaaa ctctggaaaa
    14761 atataagaca gtattggacc aagctgtaac aaatttaaat gccttagagt ttaatgattt
    14821 ggtaactatt tatgatgttg cattagtcat gcaaaagatg gaaatggtaa tgagagttac
    14881 aagtataatt gaaaaatatg tgatagaatt gggtgatgaa ggaactttag taagtatgca
    14941 attagaagaa ttaatgggta caaccagaat agaccagaaa ttaatattca aagattataa
    15001 taaagaaaac acagaaataa aagaacttat gaaaaaggtc aaaaatttaa attcagaaga
    15061 actaatagaa ttggtcaata tggcaaaact attagggtat agtggttttt cagaaagtat
    15121 ggatatgcct ataaaaacaa gaggttatag gattcttagc aaaatacata gactaccaac
    15181 agcaataata gaaaacttag taaattattt tgaaaacttt caacaaattt tagatgcatc
    15241 tattgaagaa ttagatgagg ttgaaggaat aggtgaaata agagcaacat atataaaaaa
    15301 tggactcata aaaatgaaac aattagtctt attagataga cacatatgat gaattttaaa
    15361 tgaattttac tacttttttc ttgaatataa tatacacttt ggtctataat agataagtat
    15421 aactaggggg tgaagcattg ataaggaaag taacaagaat attgtttatt ttacttggat
    15481 ttacaatagg tataacaacc tatttaacat taatgaaaga ttttgaaata ttaacatttg
    15541 gaaaagaaac atatggttat atcgcagctg tagtagcagg tataataata gccattttag
    15601 gatatcttat agaaccatgg gttgtaaata aagtaaaaga aattgctaaa atagtggata
    15661 aagaattgtc aaaatatcct cagactgata tattgttagg gtctatgggt cttatagtag
    15721 gatttgttat tgcgtattta ttaagtggat tagtaaatag aataccaata gtaggtggaa
    15781 tactatcctt actattatat ttattcctag gatatcttgg aatgaaagtt gcgcttaaaa
    15841 gtaaaaatga tttatttaat attggaaaac taggaagatt agcaaatcct attaaggata
    15901 aagataagga taaagaaaat aaaaaagaag taaaagccat tcctccaaaa gtattagata
    15961 caagtgtaat aattgatgga agaatagctg atatttgtaa gactgggttt atagaaggaa
    16021 aacttattat tcctgctttt gttttggagg aactaagaca tattgcagat tcttcagatg
    16081 atttaaaaag agtaagaggt agaagaggtc tggatatatt aaatataatt cagaaagaat
    16141 taaatataga agttgaaata agtgagagag actttgatga tatagcagaa gttgatagta
    16201 aattattaaa gcttgctcag gttttaaatg gaaaagttgt tacaaatgat tataacttaa
    16261 ataaagttgc tcaattccaa ggtgttgaag tattaaatat aaatgagtta gctaatgcta
    16321 taaaaccagt tgctatacca ggtgaagata tggttgttca agtggttaaa gaaggaaaag
    16381 aggctcaaca aggtgttgca tatctagatg atggaactat gatagttgtt gatggaggaa
    16441 gaaaatatat gaatgagact ataaaagtac tcgttacttc tgttcttcaa actcctgcag
    16501 gtagaatgat atttgcaaaa cctaaaaatt aatatgttca aagaaaccta taatttgggc
    16561 tgtttatttt aaatagatgg tccaaattta tttatttata acgataatgt ttaatgtatt
    16621 cttaaagatg gggatttaaa tcagaaagca gggagaattt atgagaaaaa agattatatc
    16681 tttcttagca acatttatca taatattaac atcagcaagt cagtatagtt ttgcagatga
    16741 tatatcaaca cgtggaaaag taatatttat agatatgaat agaactagta tgagtaatat
    16801 gttaagaata aaatcattaa gagaagaact agacaataga gggtatattg gcttgatgaa
    16861 tataagaggc gataaaggaa gtgatgatag aaggtcatat gctagtatgg gtgctggtgg
    16921 tagagctaat gtggctaatg aagaagatat taattttgaa agctcgagta aggatagaaa
    16981 tatagttttt gaatcagcta caggaaaaag tgcaaaaggt ataaataatt taactataaa
    17041 taagtctata aatgaaaatt taaactttgg agagtatggt tctgtattag ggtcattagg
    17101 acaaagttta tctgataatg gattaaaagc atctgtattg ggtaattcag atataattga
    17161 aaatggtcaa cttataaaaa atagaaactt atgtctaact gcaatggatg aatatggaag
    17221 aatacctaat ggaaatgtag atactataaa taaaaaagac ttatctatgc cttatggaat
    17281 atcaactgat tatgataaat tgattgtaga gactaaagaa gcttacaaaa ataatgatgt
    17341 gatttttgtg gagcttggag acacatatag attagattta tataaaccaa atttaaatga
    17401 aaaaacatat gagagtatga aagataacat agaaaaaaat atagatatat atttaaaaaa
    17461 tatattttct atggttgaag aaaatgacac tgtctacata gcaagtgcat ttccaagtga
    17521 tttagattat aaaaataaaa gaagactttc gccaataata aaattaaatg gagaagggaa
    17581 aggtatatta tcatcttcaa ctactagaag agaaggtatt gtaacaaatt tagatgttgg
    17641 ggttgaaata ttagacaact ttaatataaa aaatcaaaat atggttggaa gaaaatatga
    17701 acttattaac agagatgata ataaagaatt tttgatggat gaatatcaaa agatagtatc
    17761 tatttcaagc ataaggtcta caatactgaa tggttttgta agtatagttt tcttgtcatg
    17821 gatagttgct atgattgcaa ttttatttag aaagcatata tcaaaaaatt ataaagaaac
    17881 aacatttttt atattaaagg aacttttaaa aataggaata gtaatgccac tgtcatttat
    17941 gataacacca ataatgaatt tcaaaacacc attagcaata tctttaggaa taattataat
    18001 aacacttact atatatctta taagtaaagt tttaataaag aacgatttaa aaaacatgct
    18061 gttttttact ggattaacca tagtaattat ggttattgat gctgggtttg gctcatattt
    18121 aatgaaaagc aatgttatga gttatgattg tataattgga gctagatatt atggagtagg
    18181 aaatgagtat caaggtgtgg caatcggtag tgcaatattt acatttgcaa ttttacttac
    18241 atataaaaat ataccaaagt ggtctataat agttttttct ttggttatct taattacaag
    18301 tgcatctcca attatgggag caaatgttgg aagtgctatt tctgaatgtg ttgcattttt
    18361 actatttata ctattgatat ataatgtaaa gatagatttc aaaaaaatcg tattattagg
    18421 tatagcagta gtatttgtat taggagtttt tgtagcaata gatatgattt tgggaagtaa
    18481 ttcacattta ggcatgtttg taaaagaaat ttactttaat gggccaggag aaataataca
    18541 aacatttagt agaaagatag agatgaattt aaagctagct caaaccagtg catgggtaaa
    18601 tatactgtta actggaatag gtgtaatttt agttcttatg attaatcaga ttagatactt
    18661 taagcaactg atggatgagt atccaattgt atttaaagga tttatagcat caatagcagg
    18721 atgtttagta actcttttag tgaatgactc tgggattgtg tcatcagcta cagcctttat
    18781 ttatgtaatt gtacctatga taacattaag tataaatctt acagcactaa aagaataagt
    18841 actgtatgaa taatatgtaa atattaatac attaatttaa cttctttatt tacaaaataa
    18901 agaagaaagt ttataaaaaa taaattataa taaaaaagag tttatctcaa aattgattat
    18961 tctaatcaaa ttttaagata aacttttttt attataaaga taaataacat ataacctcat
    19021 attttaggta gatttttttc ttatatgttt aggagtgcat ttaaattttt ccttaaaaat
    19081 tctgtaaaat aattttgtat tagtaaatcc atgagcttct aatatactgc ataaggtatc
    19141 atttgtgtta attaaatctt tataaatatg agaaatacgc acatcattta aatactctaa
    19201 gtaagtttgt cccatatact gtttaaattt tctacaaaaa tattctggtt gtaagtgtgc
    19261 taccttagcg attttgttaa tagaaatagg cattttgtaa ttaatctttg tatattctaa
    19321 aactggttca aattttgaca aatcaagtac tgtttttttc atatttttat tacctacaga
    19381 tattttaaag tttgtatata attcaaataa aagttcaaat aataagcttg taaagagcag
    19441 attagctgca ggaggagaac taagtttaat ttctctcatg ttttctaata taagtttaac
    19501 tttacttgaa ttttttttat agttattgtc attggcatta accttaaagt caaaatagca
    19561 atttttaaaa tcagggatat atttgtttag aaaagacaat ggtacttgca ataatataga
    19621 ggtattttga taaatacatc tagttgagtg aataattcca gaattaatga acatacactc
    19681 attagctttt aaattataag tgtaaccctc catgttaatt tgtaaatcac cagaagttat
    19741 ataaattatt tctaatgagt tatgccaatg atttgctaca taactaccac tatcctgaac
    19801 ctcccatgac taaagtcaca gggttcctgc ttcatagaat tttgcatact aaaatatgtc
    19861 ttactaattc tccacaggct atccccgtag ttcctacggt tcttacatac gttatttatt
    19921 ttgaattgtt attagtctta atccttcttt taatatattt atacttgcat ttatatatct
    19981 atcgtgagtt tcattacaac taggacaaat ccattctctt atatttaagt ccttcacttc
    20041 ctcgttttta tacccacatt tattgcatat ttgtgaactt gcaaagaatt tacctacctt
    20101 tacaatttgt ctaccatgcc aattagcctt gtattctaat tgacgaataa attctgacca
    20161 tgatacatct gaaattaagc gagatagttt acgatttcta atcatattct ttacttgtaa
    20221 atcttctatg caaataatat cattctcttt tattaattta gtagataatt tttgtagaaa
    20281 atcctttctt tgattagcta tatgttcttg aagtcttgca acttttaatc ttgctttatt
    20341 tctatttaag ctaccgattg tttttctcga taattctctt tgtaatttag caaatttgtt
    20401 taatgacttc ttaagatact taggattttc tataaattct ccacaacttg agatacaaaa
    20461 ttctttaatt cctaaatcta aacctatatg attattagta ttttcaaatg cttcaatatc
    20521 tacatcagta cagcataatg atacataata tctaccactt ggctctttag atatagtagc
    20581 attaagtatt ctacctttag gtacttgttt atcccttatc ttaaccatac caagtttagg
    20641 tagttttata tgttgaccac aatacacgat atttccattt gtaaagttag ttttatatga
    20701 aaatctatta attttctttg atttaaattt aggaaatcct gccttttttt taaagaattt
    20761 tttatatgca ttatctaaat cttttaaggc gttttgtagt gaaaatttgt caggttcctt
    20821 aagccaattt aattcttttt ttaaattggt caaatcagaa ctacactgtt tataagtaaa
    20881 agtttcttta tcgtttttat aaacttctat tcttttagca agatatttat tatatacaaa
    20941 tctacaacat ccaaaagttt tgttaattaa ctcttgttgt tttttatttg gatacattct
    21001 aaacttataa gctttttcca ctactatcac ctcactt
//
LOCUS       DAEPUT010000070        20847 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.072, whole genome shotgun sequence.
ACCESSION   DAEPUT010000070 DAEPUT010000000
VERSION     DAEPUT010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20847
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.072"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(302..1573)
                     /gene="sleC"
                     /locus_tag="KRL22_002806"
     CDS             complement(302..1573)
                     /gene="sleC"
                     /locus_tag="KRL22_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HBH1273258.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            1818..2534
                     /locus_tag="KRL22_002807"
     CDS             1818..2534
                     /locus_tag="KRL22_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HBH1273259.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            2613..3923
                     /locus_tag="KRL22_002808"
     CDS             2613..3923
                     /locus_tag="KRL22_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBH1273260.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTRKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            4023..4559
                     /gene="lepB"
                     /locus_tag="KRL22_002809"
     CDS             4023..4559
                     /gene="lepB"
                     /locus_tag="KRL22_002809"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH1273261.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            4725..5261
                     /gene="lepB"
                     /locus_tag="KRL22_002810"
     CDS             4725..5261
                     /gene="lepB"
                     /locus_tag="KRL22_002810"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH1273262.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            5271..6026
                     /locus_tag="KRL22_002811"
     CDS             5271..6026
                     /locus_tag="KRL22_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HBH1273263.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KDRISKLGLSIGIHLPMELNTCENIEYIRDSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            6100..7767
                     /locus_tag="KRL22_002812"
     CDS             6100..7767
                     /locus_tag="KRL22_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HBH1273264.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMEIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            8710..9639
                     /gene="glsA"
                     /locus_tag="KRL22_002813"
     CDS             8710..9639
                     /gene="glsA"
                     /locus_tag="KRL22_002813"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBH1273265.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            9737..10300
                     /locus_tag="KRL22_002814"
     CDS             9737..10300
                     /locus_tag="KRL22_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273266.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            10788..11624
                     /locus_tag="KRL22_002815"
     CDS             10788..11624
                     /locus_tag="KRL22_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBH1273267.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKKELKMIKEILS
                     SK"
     gene            11908..12903
                     /locus_tag="KRL22_002816"
     CDS             11908..12903
                     /locus_tag="KRL22_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH1273268.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(13160..13564)
                     /locus_tag="KRL22_002817"
     CDS             complement(13160..13564)
                     /locus_tag="KRL22_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBH1273269.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            14404..15318
                     /gene="queG"
                     /locus_tag="KRL22_002818"
     CDS             14404..15318
                     /gene="queG"
                     /locus_tag="KRL22_002818"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBH1273270.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKNRQQKGYLTG
                     MEEPIIESRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            15424..17661
                     /locus_tag="KRL22_002819"
     CDS             15424..17661
                     /locus_tag="KRL22_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1273271.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTKQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            17859..19076
                     /gene="nth"
                     /locus_tag="KRL22_002820"
     CDS             17859..19076
                     /gene="nth"
                     /locus_tag="KRL22_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBH1273272.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDKK
                     DIIEKEEINKKGIDKKDIIEKKEINKKGIDKKDIIEKKEINKKEMDKKDIIEKEEINK
                     KGMNKKDIIEKEEINEKEIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKG
                     ETEKKTKKSSSNKATQKTSKETKSKFKIKNESANEKDVNKILDELEKLYPDAKCELNY
                     GTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKS
                     KSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVF
                     RVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIK
                     EDCNYYKELNETK"
     gene            19270..19740
                     /gene="trmL"
                     /locus_tag="KRL22_002821"
     CDS             19270..19740
                     /gene="trmL"
                     /locus_tag="KRL22_002821"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBH1273273.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            19776..20624
                     /locus_tag="KRL22_002822"
     CDS             19776..20624
                     /locus_tag="KRL22_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH1273274.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKKLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
BASE COUNT         8257 a         1977 c         3891 g         6722 t
ORIGIN      
        1 aaataataag tgagatttta aataaaaagt aggtttttcg ttagaatagc attttattaa
       61 acttaaaaat aaatataata ttttaaagaa atctaagttg ctaagcactg tttttaagaa
      121 gcttaaaatc ccccatttaa agttttaaga ttctaaaaaa acaagttata actaaaaaat
      181 ggctgttaag actacaatac ttataagtaa tacttatggt atatattagt tcataacagc
      241 catttttatt ttaaattaat aattttattc aataatttga gtttatgttc taaatcaagc
      301 tttaaattaa aggatttaaa gaagctattc tagttgtagc tacataaact ctggatattt
      361 cataccatgt tttaaaatct actactccgc tttgaggtaa accaaagatt ccttggaata
      421 tcttaacagc gttttctgta tctgttccat agataccatc ctctataact tttggtacag
      481 ctggataaga attagatata gcatttaact gattttgtat ggttctaaca tactgtccag
      541 aagaaccaac ttgtaatgta gtaccaggga atgacactgg tacaccactt actataggtg
      601 ctctttcaaa tactatctca tctccataga aatatcttag tatactctca tagtcatatc
      661 cttggtcacc taagtcttta ctgccccatt gagtcatttg gtcaggacat tgggattttt
      721 gtccatcaca atattgtgct aatagtggct gtcttgatgt aggaggtctt tttataaaag
      781 tattaaagat agcatctaca actacgttaa ttggttcaaa taagtttcta ttatttataa
      841 acttatggtc gtatgctgtt gttgaagtta ttgtaaagtt atatccttta tttctatacc
      901 attcagtaaa gactctattt aaagtaaatg atattatagc tattacattt gcatagattg
      961 tctgttcagg ccaagttgaa tatatttcag atgacgctat gtttttaatg tactctttaa
     1021 atggaatcca atagtttgga gctgatgaat cttctggcaa accatcatga actactataa
     1081 attcaggcac tacagggtta tctaatacaa cgaaaccagt aggaggtggt aatggtttta
     1141 agttactttc tggaatctta ggaggataag taccatatag agtatgttct cctatatcaa
     1201 aaatcaactc actttgtctt gagaaagaac gcttacttct tgttctagga gacatgggaa
     1261 ctccttgtct tgcttcaatt gtagctaaca actgtgttcc ttctatgaca actgtctcat
     1321 atccatctgc tatggcttcc actatatact ggctataagg tctaacatca gatggttgta
     1381 gagagtaatc tacatctggt gctggtaata ctaaaccagt cacttgacca gattcattac
     1441 ttcttaggtt ttggtataaa gttgatgagc tttggctacc attagacatt gaatatatgt
     1501 ttactactgc attttgaata ggtctattgt tagtagcatc aattatgctt actgttaaga
     1561 aaccatcttg catcaaatca ccctttcttt aaatgaattt agttccctta tatttcaaga
     1621 tatgaatata gcttgaaatt tgttaaataa tatagatata aatttaaatt tttttgagta
     1681 tttgagtata tttgtattta aataatttaa aataatttaa tgtatatttt agtatgtatt
     1741 taaaacacga ataagttaaa aataagtaga tgatataaat cataaataaa tcaaaaattt
     1801 tgaaaggaaa ataatctatg aagctagatt tatttttatt agcaatagtt cctatattga
     1861 tagggatgtt ttggataagg tctaaagata gatattgtag agaaccccta atccatctaa
     1921 ttaaattttt tttaataggt gcttttctaa gtgttataat tatactttta gaaaatttac
     1981 tgatgaagtt taatgtattt gaagggtatt cagaactaat atatgtatca tttgtagttg
     2041 caggacttgt agaagaaggt gtaaaagctc tgatactgat tcctgcccta attaaagaaa
     2101 aacactttac tgaaaagtta gatggtatta tttactctgt atttttagct ttaggatttg
     2161 caacaattga aaatatggtt tatatttttt ctgaaagtag aaatctagca ctgcaagttg
     2221 gtattaatag ggcagttatc tctataccag ctcatgtaat gtttgcaatt actatgggct
     2281 actatatttc taagtataaa tttgagggaa ataaaaataa aagacgtgag tatttgttta
     2341 tggcagtgtt aattccaatt ttattacatg gagtttttga tttcatattg atgatagaat
     2401 atagatgggc tattatatta cttatagttt atgtaataat tttgtggaag ataaatcttg
     2461 ataaacttga gaaatatatg aatcactcta aaaaagtgtt tttcggtaat cttaggaaaa
     2521 agaagaagaa ataaaattta aaggaaagac ataaataatt aaagtataat aaatgacaca
     2581 caagtaaagc agattgaagg gggattatag atttgacaga attaccaaag gaatttttag
     2641 aagatattga agaaatacta aaagatgaat atgatgattt tataaaaagt tatgaggaaa
     2701 gtaagactac tgggcttaga ataaatactt taaaaattga caagaaaaaa ttatttgatt
     2761 tggagttgtt tgatttgaat caaataccat gggcagaaga aggtttttat tatgatgata
     2821 aaattgacag acctggtaga aatccactgc atgaggctgg agcatactat ttgcaagagc
     2881 cttctgcaat gagtgtaata ccaaaggcag atattaaaga gggtgaaaaa gttctcgata
     2941 tgtgtgctgc tcctggtgga aaatctacat atatactatc taagctaaac gatacaggtt
     3001 tattggtttc taatgaaatt aatgctagta gaattaaggc tctaggggaa aatttagagc
     3061 gatttggagc gagaaattgt attataacaa acaccgattc taatagctta agaaagacgt
     3121 ttaatgggta ttttgataag gttattatag atgcaccttg ttctgggcaa ggtatgttta
     3181 ggaaggatga ggttgccata tcagattgga gttatgcaaa ggtagtagaa tgtcaatcca
     3241 tccaaaaaga gattataaga gatggatata aaatgttaaa gaaggatggc attttaattt
     3301 actcaacttg tactttttca agggaggaaa atgagcatgt tataaatgag tttatcagtg
     3361 aatatccaca tgcagaactt attgaaatgg aaagattatg gcctcataag ataaagggag
     3421 aaggtcattt tgttgccaaa ataaaaaaat tagaagaaga agaatgtaat gtcaaagaat
     3481 taaaaataaa aaatttagat aaagaaataa aggattatag ggagtttgaa aagaaatttt
     3541 taaaggttga tttttatagt aataaaaaaa ataaatttta tttaagagga gaaaatttgt
     3601 acctacttcc tgaaatatat ccagatacga gaaaactaaa agtattgaga tatggtttgc
     3661 atttaggggt tttaaagaag aatagatttg agccttctca tgcactatct cattacttaa
     3721 aagttgaaga tgtaaaaaat gttgaaaact tcagtgtaca gagtgaatca attcttaaat
     3781 atttaaaagg ggatgttgta aattctaatg atagtagagg atgggttttg gtttcggttg
     3841 aaggaatacc tttaggttgg ggaaaagaat cttctggtgt aattaagaat cattatccta
     3901 aaggtcttag aaaagtattt taaactatta gaaaaaagaa gtataatatt tatattgtag
     3961 gtttatggta gattattttg ctgtagattg acttaatatt taacacagag gagacgattt
     4021 tagtgggtga agcagttaaa aaagaagttg tagaatggat aaaagtgatt gtcatagctc
     4081 ttgttttggc atttgcaata actcgtttta tagtgccaac aatagtcaaa ggagaatcaa
     4141 tgtatcctac attagttgaa cgtgattatt tgatagttaa cagaattgcg tacaaggtag
     4201 gagagccaaa atacaaagat ataatagtat tcaaaaccga cttaacagag gaaaatggaa
     4261 agaaaaaaga tttagtaaaa agagttatcg gggttcctgg tgaccatgta aaaatacaag
     4321 actccaaggt atatgtaaat gataagttgt tagatgagac ttcctatata cataataatc
     4381 gtactgatgg agatattgat atcgtagttc cagaaggaaa attatttgca atgggagata
     4441 atagagaaaa aagtttagat agtagatacg atgaggttgg attggtcgac gagcatacca
     4501 ttttaggaaa ggttctagtc agattgtatc cattttctaa gataggaact attgactaaa
     4561 catataaaat ttggagcaat cgctgattag ctgaaatcac cagaccatac acaatagttg
     4621 tctatataaa aaagacaaca ccttatttag tagacttatc taaaagatag tgtttaagag
     4681 acattatcaa taaagataat ataactataa aggagaattt gtgaatgaat gaaactatta
     4741 aagaagagat tgtagagtgg ataaaaataa ttattactgc actttttttt gcatttatta
     4801 taactcgttt tataaaacca acattagtaa atggagaatc aatgtaccca acacttaaat
     4861 cacatgatta tttggtagca aacaggatga catataagtt atcagaacca aaatgtggag
     4921 atataatgat atttaagact gatttattac aagagaatgg aaggaaaaaa gagcttgtaa
     4981 aaagggttat aggtgttcct ggtgaccatc taaaaattaa ggattctaag gtttatataa
     5041 atggtaagtt attaaatgaa gtttcatata tacatgataa ttatactgaa ggcgatattg
     5101 atatggtgat tcctaaggga aaagtatttg cgatgggaga caatagagaa gttagtttag
     5161 acagtagata taaagaagtg ggattagtag atgaagaaaa tattaaagga aaagttattt
     5221 taagagtatt tccttttaca gatataggta tttttgagta ggtgatttgt atggcggttg
     5281 gtatagcgtc cttattgttt aatattgagg aggctttaaa catttgtgag agtataaagc
     5341 aaataactca tttagagatt ggaattgaca atatatctga atgtagtgag ttatgtaaat
     5401 ataaagacag aatttctaag ttaggattat ctatagggat acatttgcct atggaattaa
     5461 atacttgcga aaacatagag tatatacgag attcatggat aaattttatt gagaagatag
     5521 aatttgaact aaaaggattt gatttaaggt attttaacct tcatttggga tatgttatga
     5581 caaatagagt tagaaagaat agagacaaat atttaggaaa tagtgtggat tttttagata
     5641 aattaaatac aaattcatat gtatgtatag agaatactta ttcaaaaggt ggggattttt
     5701 caaatattgg aaatatatct tatgattttg aatatatatt taagaggatt aaaaattcta
     5761 agatttgttt ttgttacgat actggacact gtttaattga tgaggatgct tatgtaaaga
     5821 acttaaagga taaaataaga ctgatacact taagtgataa tgatggtatc aatgatacac
     5881 atgttggtat aggaagagga attttatctg aagaggggat taaagaggtc ttaacattag
     5941 atgcagaata tttagtatta gaaataaatt acgaagacat tgaagatact ataagtaaat
     6001 tgaataatat tgtaggagag ggttaaatac ctctctttat cttgttgata tgcctcatta
     6061 attaaaattt atattcatca aaaggaagga gatgttgaag tgaaaaaaat aaacttaaaa
     6121 atagaaggaa aagataagga atattcatta gaagaaaatt cccctggaat tagattggga
     6181 gatatagcaa aagaattttg tgatgagcat aagggttata taacacttgc agttgtagac
     6241 aataaactaa aagagctaaa ttgtagagtt aagaaggatt gtgagataaa ttttttagat
     6301 actactaatg aagatggaga gagagtttac tttagagtca tgtcatttat atttgtaatg
     6361 gcatgtagag aaatcttttg ggatagcaga gttacaatag aacattcact atcagatggg
     6421 ctatattgtg aagttcatat agatagaaag cttaaagaag cagatgttga aaatataaaa
     6481 aacaagatga aagagatagt aaacaacgat tatgttatag aaaaaattga agttacaaga
     6541 aatgaagcta tttctatctt tgaaaataat gaaatgtatg aaaaggcaga gcttttgaaa
     6601 tacaaagagt atgatagtgc taaagtatat aagtgtagaa actatataga ccatttttat
     6661 ggttatatgt tgccatcaac tggttatata aaatcatttg atattaagct ttataatgga
     6721 ggcgttataa ttttaggacc tagtgaagaa gataagactc ttcctatgaa atttgtacct
     6781 caacctaagc tatcaagtgt atattatgaa gcagaagaat ggtcaagact tatggaaatt
     6841 gacaaggtag tatctcttaa taaaataata gaaaacaatg aatatggaga tataataagg
     6901 acatttgaag cattgcatga aaagaagtta tcccaaatag cggatatgat aaaggatggc
     6961 aataagagag tagttttaat agcagctcca tcttcatctg gaaaaacaag ttttgctcac
     7021 agattatcaa tacatcttag agtaaataat ttaaatccta tttcaatttc tttagatgat
     7081 tattttatag atagaaaaca tactccttta gatgaatatg gaaattatga ttttgaatca
     7141 atttatgcaa tagatttaga gaagtttaac ttagacttaa agaaactttt agctggtgaa
     7201 gaaattgatg atataagatt caattttaaa gaaggtaaga gagaatacac tggtaaaaag
     7261 ataaagatag attcaaatca gccaattata ttagaaggta tacatgggct aaatcctatt
     7321 ttaacatcat ctataccaga tgaagataaa tttaagatat acataagtgc ccttactcaa
     7381 ataaatttgg atgaccataa tcgaatccct actgctgatt tgagaatgat aagaagaatt
     7441 gttagagact ataattttag aggatatagt gctgataata ctattttaca atgggcatca
     7501 gttagaagag gagaaaagaa gaatatattc ccgtaccaag aggaggcaga tgctatattt
     7561 aactctgctt gtgtatatga attggcagtt ttaaaacgat ttgcgaaacc tttgttggaa
     7621 gagataaagg aagataatcc tgcacatatt gaagctacta gattactaaa gtttttgcag
     7681 tattttgttg aattggacga tacttctgac ataccaggta tttcaattct tagggaattt
     7741 attggaggaa gtaaaatagt tgattaatgt gtgtactata gattgtttta tgaagattaa
     7801 atggcatagc aagtagtgtg attggtttat gttaagtata ttaagtgtaa agtggagaat
     7861 taaattgata cagattttaa agtttgagtt gatatataaa aaggcttgtt ttatactttt
     7921 gtatgaagca agctttttat tttaaatttt acttttttgt ttaatatttt gttagtttat
     7981 gtgattattt tttaaaagag taaaagagta aaagagtaaa agagtaaaag agtaaaagag
     8041 taaaagagta aaagagtaaa agagtaaaag agtaaaagag taaaagagta aaaggtgttg
     8101 ggttagaaat ttttggtgtt ataaaaattt aaattactgg attattagat tgctggattg
     8161 ctaaattact aggttgttaa attattgaat tattaggttg ttgaattact aaattactag
     8221 gttgttaagt tactggatta tttagatagt tagattacta ggttgttaaa ttattgaatt
     8281 attaggttgt tgaattacta aattactagg ttgttaagtt actggattat ttagatagtt
     8341 agattactag gttgttaagt tactggatta ttagatagtt agattactag gttgttaaat
     8401 tattgaattg ttagattgtt gaattactaa attactaggt tgttaagtta ctggattatt
     8461 agatagttag attattagat tgctaaatta ttaggttgtt aaattactgg attattagat
     8521 tactaaattg ctaggttgtt aaattattga attattaaat tattaagctc tttaaactat
     8581 ttaaattgtt tgaaaaatga attgattctt gtagaaaata attttaaagt ataatttttt
     8641 ttaacattgt tttattatag tataaacttg tgctaaaata gaatatataa cataatataa
     8701 gaggtgcata tgaatacgtt agatgagaca ttattaaaag aaattataag ttctaataag
     8761 aagtatacta attatggaca agtcgctagt tacataccag aattgaaaaa cgctagaaga
     8821 aatgatttag gaatttgtat catagatagc gaaaataatc tttatagtgc tggaaactgt
     8881 agcacaaagt ttactataca aagtatttca aaaccaattg tgcttgctat ggcacttatg
     8941 gataatgatt gggaagacgt tttttcaaac gttggaatgg agccaagtgg ggacccattt
     9001 aattcaataa tgaaacttga aattaatgac acaaaaaaac cctgtaatcc aatgataaat
     9061 gcaggggcta tagtaaccac ttcccttata aatgggagtt gtttagaaga aaaagaagaa
     9121 agaatgctta gtttctttag aaagttagca aaaaatgata atataggaat aaactatgat
     9181 gtctataagt ctgaaaaaat gactggagat agaaacagag ctatggctta cttattgaaa
     9241 agtgatggat ttatcagagg gaatgtagaa gatgttctag acctttattt taaacaatgc
     9301 tcaattgaga tagattctgt agatttagcg agaattggaa taaatcttgc aaattatgga
     9361 gtagatatag aaaatggtga gcatttaatg agtgaaatgg tttctaggat tgtcaagaca
     9421 tttatgatga cttgtggaat gtatgatgct tctggggaat ttgctattaa agttggcatt
     9481 cctgcaaaat ctggagttgg gggtggtata atggcttctg tgccgggacg catggggatt
     9541 ggtgtttatg gacctgcgct tgacaaaaaa ggtaacagcg tcgcaggagt taaagtttta
     9601 gaggagttgt caaataaact caaattaaat attttttaaa atattaagaa aggatttttt
     9661 tgacaacaac atataattta atatataatt aaattgtaaa gaaatatgaa ttaaataaat
     9721 tttttaggag gggtcaatga aagaggtatt ggtattacga gatttggagt gcataaaggc
     9781 tattgcgcat ccacgtagaa tagatattct aaaagcattt gacaaatcgc cattgtcagc
     9841 aaaacaatta tctcaattat tggaagaacc tcatgcaaaa ataaactacc atataaaaat
     9901 gttatacaaa gttggtattt tagaattagt tgaggaaaaa ataaagtcgg ggattgtgga
     9961 aaagtactat tatccaagtg caaaaaatgt ggttataggg aataggatac ttaatttttc
    10021 tttagacaat ggggaagaaa aagaagaatt gtacatatca aaatttgaaa atatgagtga
    10081 agttttttat aaggcagcag aggaagatgt tttagaaaat gaaaatatag ttgattatca
    10141 tgatatttct cttactcatg atgaattagt tgaacttagt gacactatga agtcaaagat
    10201 agatgaaatt ttaaataaaa gacaacacaa tgttgaaggt tctaagtatg atatagctat
    10261 ggttatagtt cctactcttg aggaggaatg tcctagttag agaattaatt atggattaat
    10321 taaagatata atattagaga ttgaacatca aaatttactt aataatcaaa aaatagtttt
    10381 tggtatgggt aaaacaatga tttttaatct ctattttttt gtttttttat acctattgta
    10441 tttgtaaata atatgtatag tgtaagatgt atacactatc taagaagtgc ttagataata
    10501 tacaaagtat gtaagattat aatatttgaa attgattaaa atgggtataa ttaaagtgta
    10561 aatattaaaa ttaaaaatta atataaatta aatcaatgct agaaatatgt taaaagagga
    10621 atgagattag ttgggataga acatccctta gagcttatga atttttagtg aaaaagtact
    10681 atcaaatagg aatctccatc ttcatatgtt ggctaaatgt agttaaggtg gagtagttca
    10741 aaattaaaat tgagtacaag tcgtagtaca aataaaagga gattaatatg attaaattag
    10801 gaacacatct ttcaatagca aaaggctttg ctaatgcggc tgagacagct gtatatattg
    10861 gtgcaaatac atttcaattt tttagtagaa atccaagagg aggaaatgct aaagaatttg
    10921 atgaaaaaga tataattaaa tttcaagaaa ttagaaaaga aaataatttt gcaccactgc
    10981 ttgcacatgc accatatact atgaatctgg gtggtacaaa ggatgatgta tacgaatttg
    11041 caacaagggt gatagatgag gatataagaa ggatggactc attaggaatt gaatacatgt
    11101 gttttcatcc tggaagtcat gtaggtggtg gtgtagattt tggtatagat agaatagtaa
    11161 aaggattgaa caatgccata aagggtgatg aaaatataac tatacttctt gaaactatgt
    11221 cgggaaaggg aactgaaata ggttttaaat ttgagcaatt aaaaagtata atagacaaaa
    11281 ttgagcataa agaaaaaata ggtgtgtgtc ttgatacatg tcatattttt tcagctggtt
    11341 atgatatagt gaatgattta gatggggttt tggaagaatt tgataaggtt ataggcatag
    11401 aaagattgaa aactgtccat ctaaatgata gtatgatgcc atttggagac aaaaaagaca
    11461 gacatgctcc tataggggaa ggaaagatag gattaaaagc attaattgat tttatggaac
    11521 atcctagtct aaaacattta ccatttttct tagaaactcc ttttgatgat gaaggtcaca
    11581 agaaagagct taaaatgata aaagaaatac tatctagtaa ataaaccttt attaaaaata
    11641 tgtgaaatac ttcaccctca acataattag ggtggagata caatcatgaa atgtgataat
    11701 ttaaattaat ggataggaat aacaaaaatt gtatacaaat taactgggta taaagtatga
    11761 ttatattatg aatagactga tataaaatat aattatatta tgaatagtat gtaaatatat
    11821 tgcaaagatt ctcataattt gttgtataat taaagatgac atatttatat tatataaaaa
    11881 attattaaaa gttaggtggg gaaagatatg agaaatttag gcaatactaa catgaaaata
    11941 aagagagttg gctttggggg cattccaata caaaggatta ctcaagatga tactaactta
    12001 gttataaatg agttagaaaa acaaggaata aactttattg acagtgcaag agggtataca
    12061 ataagtgagg aagcaatcgg aattgccatt gaaggaaaaa gagataaatt tttcttagct
    12121 actaaaagta tgtccagaga ttatgattca atgaagagag atgttgaaat aagtttaaat
    12181 aattttaaaa ctgattttat agatttatat caattccata atgttaaaga agaggagtat
    12241 gataatcttt ttaaagataa aatggcttat agtgcccttt tagaggcaaa ggagcaaggt
    12301 aagataaaac atattggtat aactagtcac aatttaaata ctatagaaaa agctatagaa
    12361 gatggaaaat ttgacactat acaattccct tacaatatag ttgaaggaca agcagatgaa
    12421 gtgtttaaaa aagctcatga aaaaggaatt gggataatag taatgaaacc tttagctgga
    12481 ggtgctttag acaatgcaac actggctatt aaatatatac tatctaaaga ttacatagat
    12541 gtagttatac caggtatgga gagtgttgaa caggttagac aaaatgtcgc tgtacttgaa
    12601 aatcttgtgc tagatgaaaa agataataag gaaattgaag aaataagaaa ttctttaggt
    12661 aaaaaattct gtagaagatg cgaatattgt atgccttgtg ctgtaggaat aaatatacca
    12721 ttgagttttt tatgtgaagg ttattatact agatatggat taaaagagtg ggctaaagaa
    12781 aaatatgagg ttatggatgt taaacctact gagtgtattg actgtgggct ttgcgagagt
    12841 agatgtccat atgaacttcc tataagagaa atgcttaaga ctgttgttga aaagctagga
    12901 tagattttat ttattgaaat cggtgtatta aatttactcc gatttctttt tattagatgt
    12961 ggtcttatat acaaatatta aatttacata gttatagcta ttatataaat ttaatatttg
    13021 tttaatactt attaaatatt tacttaatgc tttttaaaaa catttgtttg agtatagaca
    13081 taacacaatt attattgttg tattagtata gtttcaaata ctggagtatc aatataatgt
    13141 cgaataacac ataaaatctt tatttttcaa aaatattata ggatatatcg tatttagata
    13201 ctggataaag ttcaatttca accctagggt tatctttatc tataaaatca aataaaagta
    13261 ctggcttaag ttgtttatca ttttttatta ttccactttt ttcaatacca tcacaaatac
    13321 tttttggata attatgtaaa tcccccattc tcttatttgg gaagaataat ttcaagactg
    13381 ttattagatt ttcttcaaca gtttcccctt gatactgttg gtttataaaa cctgcaatca
    13441 tgttttcgta tgcaagatac ttagaatatt ttccctttga aggcatccat gcttgaccat
    13501 ttatgttatg aagcttaaaa ttagatttac taataggtct acctggaatt gttattttaa
    13561 tcaaattttt caccatcctt atacagtatt tattataatc tgtatatgat ttaaaagcaa
    13621 attgttattt aaagtgtttt tacagagctt gtttgtaaaa ttttccactt tagatgtggt
    13681 aatataagat aagtattttg cttacaaatt ttaaaatttg atatatgatg gacatattca
    13741 tattagacta ttataagacc ttcataatat taataagtat agtttagtaa agagagtaaa
    13801 aagaaatcca tataagtcaa gtaaagattt aataaatggc aatgtaaatg ggatattaat
    13861 tataagaaaa aatcaatctt tttgcttaac tatagaaaga atgtcaaaat ataactaatg
    13921 atatttgaag ttttagagtt tatattaaaa ggtaagaagg ttaagtgggt aaaaaaggtt
    13981 gaatagatta aaaaggctaa gtatctaaaa gagttaagta ggtaaaaaag ttaaataagt
    14041 aaatgaaaaa ggctaagtat ctaaaagagt tagtaggtaa aaaagttaaa taagtaaata
    14101 aaaaagatga agtatctaaa agagttagta ggtaaaaaac taaataggta aaaagatgaa
    14161 gtatctaaaa gagttagtag gtaaaaaatt aaataggtaa aaagacgaag tacctaaaag
    14221 agttagtagg taaaaaaatt aaatagataa aaagacgaag tatctaaaag agttaagcag
    14281 gtaagaaaat tgaatagcta aaaagattaa gtatttaaaa gagttagtag ctagaaaagg
    14341 ttaaaaagac taaaaaaatt aaataaattt aaaaagtcaa ttagattaaa aaggaataat
    14401 tttatggata ataaggaatt aaaagcattt tgtaatttaa taggattaaa ctgtgtagga
    14461 gtagcagggg tagataaata tgataattta gaaaagatac ttaagaacag acaacaaaaa
    14521 ggttatttaa ctggtatgga agaaccaata attgagagca gaattaaccc aagacatata
    14581 atgaaggatg ctaactctat aatagtctgt gcatttccat atcatataaa tagacaagaa
    14641 aagaataaaa attcaaattt atcaaaatat tgtcatggaa aggattatca cattgtagta
    14701 aaggactttt tacaacaaat ttgtgattat atttctaaaa cagtaacaga ttttaaatac
    14761 aagttatttg ctgataatgg accattagtt gacaggtatt tagcttattt atcaggaata
    14821 ggatattttg gaataaataa taatatcata actgatgaat atggttctta cgtatttata
    14881 gggtatatag taaataatta taaatttgaa gaagataaac cactagaaaa aagttgtttt
    14941 aaatgtggta agtgtgtaaa atattgtccg ggaaatgcta tattgggaaa ttatgatatg
    15001 aaccccaaaa aatgtttatc atatataact caaaaaaaag gagatttgtc agagaaagaa
    15061 aaagttgttt taaagaatgg caaaaaggta tttggatgcg atatttgtca agaagtatgt
    15121 ccacataatg ttgaaatacc aacaactcat attttggaat ttaaagaaaa tataatagat
    15181 tatttggatt atgatgagat acaaaatatt tcaaataaag aatttaaaag gagatatgga
    15241 gatagagctt ttagctggag aggtagaaat ataataaaga gaaatatgga aataatttta
    15301 gataagtatg atgactaata ataagagtct gtttcatata ctttaatgtg tatttacttt
    15361 aacacttgtt gtgtaaaagt catattatat cattaaagtt aaatatgggg aggtggggga
    15421 atattgaaat ataataatac atctgaaata aatccactag attatatatt gggtcaagaa
    15481 agagctgtag aagctatgga attagggttg aaaataaata atccagcgta caacatatat
    15541 atagctggtg aacctggaac tggtaaaagt acttatgcct taaaggtttt aaatgagtat
    15601 gcatccaaaa aaaatacgca taaagattgg tgttatatat ataattttga aaaccctaga
    15661 gagcctatta tagttgaatt agaaaagggg tttggaagag aacttaagaa agatatggag
    15721 aaattaattg aaagtctttt agaagatttt aaaaatgcgt ttgaaagtga aaattttgaa
    15781 atagaaaaaa ataaacttct ggatgaatat gaaatagaaa aagatatgct tttgaagcaa
    15841 attaaaaaat atggagaaga aaaaggattt aaattaaaac agagtaaaat gggaatagtt
    15901 tttatccctt tgaaagaaga ggaagatgaa agtgatgagt ctgatgaaga gttttacaaa
    15961 gctaaaagag aactagaaaa tatggcgata caggtcgtat ataaaattag aaacttagaa
    16021 gaaatagctg aaaaagcagt gttagagctt gaagaagaga tagctaaact tgtagtagaa
    16081 cctcatatca agagattgtg tgaaaaatat gaaaattatg ataagattca aacttatctg
    16141 gaaaatataa agaaagatat aatagaatat atgtatttat tctatttaga tgaagaggag
    16201 ttaaaagata agtatgataa agagcatttt attaaatata aaattaacct atttgtagac
    16261 aatggaagct caaagaataa agaatcagca cctgttgtag tagagataaa cccaagtcca
    16321 gcaaatctat ttggaaaggc agagtatgat tatgcaaatg gaaatataaa gactgatttc
    16381 acaaaactat tatcaggagc atttcatagg gctaatggtg gttatttagt actttatgca
    16441 gaccaattac taaaatatac aatgtcttgg gaaattctta aaaagacttt gcagactaaa
    16501 aaagtaatat tggaaacaca aacagcaatt aaaccagaaa atatgccatt ggatgttaaa
    16561 ttagtactga ttggaagcca ctatatatat gatattttat atagatatga tgaagatttt
    16621 gaaaaatatt ttaaagtatt tgtagacttt gatagtgaaa tggataaaaa tgaagataat
    16681 gaagaaggaa tagcaagatt tatagcatac caatgtgata agaataattt aaggcatttt
    16741 actaaatcag cagttgaaga ggttattaaa tttagcacta gattatctgg tgatttagaa
    16801 aaattatcaa ctaagtttaa taaaataatg gaagttgtaa tagaaggaag tgcttatgca
    16861 gagtttagaa attcggagta tacaaagcag tgtgatgtta aaaaagcaat aagtgaaaag
    16921 agaaaaagaa tcaatagagt ggaaacacat atggatgaat caattgaaaa tggatttact
    16981 ctaatagaaa cagagggaag aaaagtagga gtgataaatg gtttgtcagt cttaagtaca
    17041 ggagaatact cttttggtag agcttcaagg attacagcga ccactagccc aggaagtaaa
    17101 ggcatagtaa atatagaaag agaagtaaat atgagtggct ctatacataa caaaggagta
    17161 cttatattag gtggctatct ttctgagaat tttgcacagg atttactatt gtcactaaat
    17221 gcatatgttt gttttgaaca aaattatggt ggaatagatg gagatagtgc atcttctgca
    17281 gaattatatg tactattatc atctcttagt ggagtatcaa ttaaacaaaa tattgctgtt
    17341 acaggttcta taaatcaaaa gggtgatata caagtagttg gtggtataag tgaaaagata
    17401 gaaggatttt attctatatg taaaactaaa gggttaaatg gtgagcaagg cgtcataatt
    17461 cctagaaaaa atcaaagaaa tctcgtttta tcagatgaag ttaatgatgc agtgcgagat
    17521 ggaaaattta agatatatac tgttgaaaga gtagaagagg ctatagagat attgacagat
    17581 gttaaatttg aagaaataaa gaaattggta aaagaaaaat taatatcttt cagcaagata
    17641 caaactgtgt caaaagaata agtttattat agaatttaat gggtatttat gtataataaa
    17701 aagcaagaac tttaataggt ttttgctttt tttgtaaata tatataaatt aaattcttat
    17761 tttgtatgtt ttatatattg atgtttattt ttttgttgat atgattaaac tatttataaa
    17821 tagcgtttta taaattggta ttttgaaggg ggataattat gaaaaatgta aatctaaaag
    17881 agataaatga aaaagatgta attttggaag aagagataaa taaaaaagga atggataaga
    17941 aaaatataat tgagaaggaa gagataaata aaaaaggaat agataagaaa gatataattg
    18001 agaaggaaga gataaataaa aaaggaatag ataagaaaga tataattgag aagaaagaga
    18061 taaataaaaa aggaatagat aagaaagata taattgagaa gaaagagata aataaaaaag
    18121 aaatggataa gaaagatata attgagaagg aagagataaa taaaaaagga atgaataaga
    18181 aagatataat tgagaaggaa gagataaatg aaaaagaaat agataaaatg attggtaaaa
    18241 aagatgagat aattgatgag aaagatatag agaattttat ggatattgaa gaagataaaa
    18301 aaagtatcaa agtaagtaaa aaaagtacta aaaaaggtga aacggagaaa aaaacaaaga
    18361 agagtagttc taataaggct acacaaaaaa caagtaaaga aactaaaagt aagtttaaaa
    18421 ttaaaaatga gtcagcaaat gaaaaagacg taaataagat tttagacgag ttagaaaaac
    18481 tgtacccaga tgctaaatgt gagttaaatt atgggacagc ctttgaactt ttaatagcaa
    18541 ctattttatc agcacaatgt actgatgtaa gagtgaataa agttacttca gagttgttta
    18601 aaaagtacaa cacagctaga gactttgcta atttgagcat tgaagaaatt agtaaagaga
    18661 taaagagttg tggtctttac aaaagcaagt ctcaaaaaat aaaggataca tctgaacagc
    18721 tatgtgaatt atatgatggt gaagtacctg atagcttaga aaagcttata aaattacctg
    18781 gtgttggaag aaaaacggca ggggttgtac ttagtaacgc ttttaatcat ccagcaatag
    18841 ctgtagatac tcatgtattt agagttagca atagaatagg aatagtggac gagccaaatc
    18901 ctcaaaaaac agaatttgca cttatggaag ctataccaaa agaaagatgg tcacactcac
    18961 atcatgtatt aatttttcat ggaagaagaa tgtgtaaagc tagaaatcca gaatgtgcaa
    19021 gttgcccaat aaaagaagat tgtaattatt ataaagaact taatgaaacg aaataacttt
    19081 tagaaagtaa gttgtacaag agggattttc tgatataata atacttgtga aaatgttaga
    19141 taaaaaacta ttatatacat gaaataaaaa ttattattaa cattatttta tataatagta
    19201 taatattatt gttattctgt ttataaaata aaatttgata aataaaagcg atacttaggg
    19261 aggattaaaa tgtcattaaa tatagtatta gtagaaccag aaatacctca aaatacagga
    19321 aatataataa gaacctgtgc agcaacaggt tcaactttac atttagtaaa accactgggt
    19381 ttttcattgg atgataaaca cctaaaaaga tgtgggcttg actattggga tatagctgat
    19441 atacaatatt acgatagctt tgaagaatta caagaaaagt atccaaatag taaatacttt
    19501 ttttctacaa caaaggctaa acagtcacat tcagatgtga aatatgaaga aaattgtttt
    19561 atagtatttg ggaaagaaac aaagggatta ccagaacctt tgttgaaagc aaatatggat
    19621 acttgtatta gagtgcctat gttggatgtt gaaaaagcta ggtcattaaa tttatcaaat
    19681 tcagttgcta ttgtagtgta cgaggcttta agacaaatag gatacccaaa tatgaggtag
    19741 tttcaacaag cctaaatgag aaaggagcat acttaatgaa aaatctaaag ataatctgtg
    19801 acagtttatc ggacgtgcca aaagatttgt tagataaata tgatatagat atagtttcat
    19861 taacagttat actggaggaa agagaataca aggatagaat tgatatatct ggagatgaat
    19921 tttataaaaa gcttagagaa gaaaatgtat atccaaaaac ttctcaagct acttatgccc
    19981 aatttaagga aatttttgag aaatatacaa atgaggatag agagatactt tatatagcag
    20041 ggtctgccac agctacaggt acgtatcaaa gtgctgtaat ggcaaagaat gatgtagatg
    20101 gtaaaatata tacatatgac tctaacttgc tttgtatggg aactggttta cttgtaataa
    20161 aagcaggaga acttgcaagt gaaggaaagt ctgttgctga aatattgcct gttttggatg
    20221 aattaaaaga gaaggctttt gttatatttt cagtagatac attggaatat ttacaaaagg
    20281 gaggtagaat atcatctact aaggcagcaa taggaagtat attaaatata aaaccgattc
    20341 ttgaaataag agatggatta gtttcgcaaa tatctcaagt aagaggaaag aagaatgtaa
    20401 tttctaagat gatggaattg ataaaatcaa attgtggtga tgatttatca gaccaaattg
    20461 tatatatagg atatagtgat gattttaagg aaaaagaaca attatctaag gttatgcaag
    20521 atgaattaag acctaaagaa attagatttt tccaaattgg tgtgtgtata ggtgcacatg
    20581 ctggtcctgg tgttactggt atcatatgct taaaaaataa ataatatatt tttggatgac
    20641 attatttatt tttttattaa attaggatag aatattaatt attgagatgt taaattggat
    20701 ttattttgga tgaaattaag tgttgatata ttagatttag tttgtaggga agtgtgtaaa
    20761 tagataagaa tctattgcac acttttttat agtaagattt attaaaaaaa tttcaaaatg
    20821 tacttgtaaa ttgtatataa aaaaatt
//
LOCUS       DAEPUT010000071        20828 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.073, whole genome shotgun sequence.
ACCESSION   DAEPUT010000071 DAEPUT010000000
VERSION     DAEPUT010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20828
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.073"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..1065
                     /locus_tag="KRL22_002823"
     CDS             <1..1065
                     /locus_tag="KRL22_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1273275.1"
                     /translation="QELINKTFGCCRFVYNKYLAKRIDVYKSDKETFTYKQCSSDLTN
                     LKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKFKSKKINRFSYKTNFTNGN
                     IMYCGQYIKLPKLGMVKIRDKQVPKGRILNATISKEPSGRYYVSLCCTDVDIEVFENT
                     NNHIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLK
                     VAGLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEF
                     IRQLEYKANWYGRKIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRD
                     INASINILKEGLRLITIQNK"
     gene            1183..1488
                     /locus_tag="KRL22_002824"
                     /pseudo
     CDS             1183..1488
                     /locus_tag="KRL22_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
     gene            1501..2406
                     /gene="truB"
                     /locus_tag="KRL22_002825"
     CDS             1501..2406
                     /gene="truB"
                     /locus_tag="KRL22_002825"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBH1273276.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCDVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            2537..3466
                     /locus_tag="KRL22_002826"
     CDS             2537..3466
                     /locus_tag="KRL22_002826"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBH1273277.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGYDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            3570..3827
                     /gene="rpsO"
                     /locus_tag="KRL22_002827"
     CDS             3570..3827
                     /gene="rpsO"
                     /locus_tag="KRL22_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBH1273278.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            4067..4912
                     /locus_tag="KRL22_002828"
     CDS             4067..4912
                     /locus_tag="KRL22_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH1273279.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELFEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            5037..7148
                     /gene="pnp"
                     /locus_tag="KRL22_002829"
     CDS             5037..7148
                     /gene="pnp"
                     /locus_tag="KRL22_002829"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBH1273280.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            7414..8157
                     /locus_tag="KRL22_002830"
     CDS             7414..8157
                     /locus_tag="KRL22_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1273281.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            8315..9562
                     /locus_tag="KRL22_002831"
     CDS             8315..9562
                     /locus_tag="KRL22_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH1273282.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTKNLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            9597..9842
                     /locus_tag="KRL22_002832"
     CDS             9597..9842
                     /locus_tag="KRL22_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH1273283.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            9852..11075
                     /gene="dapG"
                     /locus_tag="KRL22_002833"
     CDS             9852..11075
                     /gene="dapG"
                     /locus_tag="KRL22_002833"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH1273284.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIESVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            11188..11922
                     /locus_tag="KRL22_002834"
     CDS             11188..11922
                     /locus_tag="KRL22_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HBH1273285.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            12045..14456
                     /locus_tag="KRL22_002835"
     CDS             12045..14456
                     /locus_tag="KRL22_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBH1273286.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDDEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKAEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVIE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            14459..15517
                     /gene="mnmH"
                     /locus_tag="KRL22_002836"
     CDS             14459..15517
                     /gene="mnmH"
                     /locus_tag="KRL22_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBH1273287.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            15511..16845
                     /gene="rimO"
                     /locus_tag="KRL22_002837"
     CDS             15511..16845
                     /gene="rimO"
                     /locus_tag="KRL22_002837"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBH1273288.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            16832..17374
                     /gene="pgsA"
                     /locus_tag="KRL22_002838"
     CDS             16832..17374
                     /gene="pgsA"
                     /locus_tag="KRL22_002838"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBH1273289.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNIPNKFLIACIIFVIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            17662..18708
                     /gene="recA"
                     /locus_tag="KRL22_002839"
     CDS             17662..18708
                     /gene="recA"
                     /locus_tag="KRL22_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBH1273290.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            18884..20425
                     /gene="rny"
                     /locus_tag="KRL22_002840"
     CDS             18884..20425
                     /gene="rny"
                     /locus_tag="KRL22_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBH1273291.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
BASE COUNT         8540 a         2106 c         3991 g         6191 t
ORIGIN      
        1 caagagttaa ttaacaaaac ttttggatgt tgtagatttg tatataataa atatcttgct
       61 aaaagaatag atgtttataa aagcgataaa gaaactttta cttataaaca gtgtagttct
      121 gatttgacca atttaaaaaa agaattaaaa tggcttaagg aacctgacaa attttcacta
      181 caaaacgcct taaaagattt agataatgca tataaaaaat tctttaaaga aaaggcagga
      241 tttcctaaat ttaaatcaaa gaaaattaat agattttcat ataaaactaa ctttacaaat
      301 ggaaacatta tgtattgtgg tcaatatata aaactaccta aacttggtat ggttaagata
      361 agggataaac aagtacctaa agggagaata cttaatgcta ctatatctaa agaaccaagt
      421 ggtagatatt atgtatcatt atgctgtact gatgtagata ttgaagtatt tgaaaatact
      481 aataatcata taggtttaga tttaggaatt aaagaatttt gtatctcaag ttgtggagac
      541 tttatagaaa atcctaagta tcttaagaag tcattaaaca agcttgctaa attacaaaga
      601 gaattatcga gaaaaacaat cggtagttta aatagaaata aagcaagatt aaaagttgca
      661 ggacttcaag aacatatagc taatcaaaga aatgattttc tacaaaaact atctactaaa
      721 ttaataaaag agaatgatat tatttgcata gaagatttac aagtaaagaa tatgattaga
      781 aatcgtaaac tatctcgctt aatttcagat gtatcatggt cagaatttat tcgtcaatta
      841 gaatacaagg ctaattggta tggtagaaaa attgtaaagg taggtaaatt ctttgcaagt
      901 tcacaaatat gcaataaatg tgggtataaa aacgaggaag ttaaggattt aaatataaga
      961 gaatggattt gtcctagttg taatgaaact cacgatagag atataaatgc aagtataaat
     1021 atattaaaag aaggattaag actaataacg attcaaaata aataacttat gtaagaaccg
     1081 taggaactac ggggatagcc tgtggagaat tagtaagaca tattttaata tgcaaaattc
     1141 tgtgaagcag gaaccctgtg actttagtca tgggaggttc agtcaaaggt atctagtata
     1201 gttttaactc aagacatgat gaatagaaat aatattagct ttaatgatgt tgatggaata
     1261 acaacatata caagagacat aaaaggtata gaagttggaa ttttatttaa agagaaaaaa
     1321 caaaatgaaa ttaaagtgag ttttaggtca aaaaattatg ttgatgtaag tgaaatagcc
     1381 aagttatttg gtggtggtgg tcatgtaagg gctgctggat gtactattag agatagtatt
     1441 gataatgcaa agaaaatggt actagaggca gtgttaaaat caatttaagg tgacagtaaa
     1501 atgaataaga ttataagtat attgaaaccc acaggtatga catctcatga tgttgtaagt
     1561 agagtgagaa agattttaaa tataaaaaaa gttggtcata caggtactct tgacccagat
     1621 gcttcaggtg ttttaccaat ctgtataggg aaagctacaa aagtatgtga cgttatttta
     1681 aacaaagata aatcgtatat atgtgagctt actttaggta taagtacaga tacttatgat
     1741 gcttcaggtg aaattttaaa aaaagttgat gattttaaat ttagtaatga agacatagaa
     1801 agagcttttg atacacaaag aggagagata aatcaacttc ctccaattta ttcagcttta
     1861 aaggtaaatg gaaagagaat gtgtgattta gtaagaagtg gtagacaatc tgaaattact
     1921 ttaaaaacaa gaagagtaaa tataaaagac ataaaaatac taagtataaa aggtaataaa
     1981 gtaatgtttt atgttgagtg ttctaaaggg acttatgtga gaagtatttg ccatgatata
     2041 ggagaatatc taggttgtgg agctcatatg tcgtttttga atagaacatc ttctggtaaa
     2101 tttgacttag ataactcaat aacattagaa gaattagaat tattttatga aaataaaact
     2161 ttagacaaat acttatatga tatagattat gtccttgatt cgtttaatta tgttgtatta
     2221 aaccctaatg ctataaaata ttatagtaat ggtggctcaa tagatgataa aaggttttta
     2281 aaaaataatt tcgataaaga tgatgaattt gtaagagtat acagtacaga taatttctta
     2341 ggattaggaa agttatcaaa acacaataat acaataagtg ttaaaagtga taagatgttc
     2401 atataaccaa tgtatttaaa aaaacaacaa aagagatagt actataataa cttctatagt
     2461 ctatctcttt tacttatgct ataatagttt gtgaataagt taagagtaaa ttatatttta
     2521 gcggggaaca tttattatgg tgattataaa atctataaaa gaaatagcaa acataaaaga
     2581 aagtgtcatt accataggaa attttgatgg tgtacacaaa ggacatcaag ttcttatagg
     2641 aaaaacagtt gaacatgcaa aaaaagaaaa tatacagagt attgtattta catttgcaaa
     2701 tcatcctgta aattacttta gaccaaactc aacaaaaaat attataagca atgatgataa
     2761 aataaaatta ttagaagatt tgggaataga tatagttgta atcataccat ttgatgagta
     2821 tatgactaaa atacctgcaa aggatttcgt agatgagata ctagtaaaaa aattaaaagc
     2881 taaaaagata gtaattggat atgactttac atttgcaagg gcaaaagaag gcaatgttaa
     2941 tctattaaaa agcttagaac atgaatttgg ttttgaggta gaagtaataa aacccatcaa
     3001 aatcaatgat gtaagagtga gtagtactta tattagaagt ttagtatccc agggtgatat
     3061 ggctaatgtc aaggaatatt tgggtagaaa ttacaagtta gaaggttgtg ttatacattc
     3121 taaacacctt ggaagaacta taggattccc aacggcaaat attgacctta agaataatat
     3181 gctcgttcca aagagaggta tttatgcttc tattgtacat attggagatg agacttattt
     3241 tggtgctaca aatgtaggct ataacccaac agttaatgga aaaactttgt ctattgaaac
     3301 aaatatttta gagtttgata gagatattta tggggaaaat ataattgttg aatttttgga
     3361 aagaataaga gatgaaagaa agtttaattc aatagatgac ttaaaaaatc aattgtataa
     3421 tgatacaaat tatgtgtatg aaaactatgt ttgcaaaaac aagtaatgta tgataaaatg
     3481 attaaggaaa ataaccatta ctcggcattt gaatactcca atcaatgctt agtaataggc
     3541 gtttctaaaa aaatacggag gtaatctaaa tgataaacaa atcagaaata ataaaagaat
     3601 atggaagagc tgaaggggat actggttctc cagaagtaca aatagcttta ttaacagcta
     3661 gaataaacga gttaaatgga catttaaaaa ctcataagaa agaccaccat tcaagaagag
     3721 gactattaaa aatggttggt agaagaagaa acttattagc ttacttaaag gaaaaagatc
     3781 ttgaaggata tagagcatta atagctaaat taggattaag aaagtaattt cattctttat
     3841 aaaaaagcag gtatagtgta tacctgcttt tttatagtta attcattata aagtaaaata
     3901 gttaataata aaagtagttt atatgttata aaaaattata aaatgaataa tattgggtaa
     3961 gaatattaaa atagtataca aatacataat caatttaaaa ggaaagacag gataaatata
     4021 gaaattttat aacaggataa ttagttggaa taaggaggat attattttga aaataaagtt
     4081 agtatgcgat agtttgtgcg atattccaga tgaaatatca gaaaaagatt atatagagat
     4141 agttccactt acagttattt ttaatgatag ggaatatata gaaggagtag atataaagaa
     4201 agaagagttt tataaaaaag taaaagaaat caagcaaata cctaaaactt cacaagctac
     4261 atatatggag tttaaagaag tgtttgataa gttcataaca gaaggttatc atataatctg
     4321 tatgacaggg gctgcaaacg catcaggaac ttttcaaagt gctatgatag ctaaaaatga
     4381 tgtaaatgaa aatgaaaaaa tacatatatt tgatactaga aatttatctc taggtagtgg
     4441 acaatatgtt ataaaggcat gtgaactttt tgaagaagga ctgggatttg aagaaattat
     4501 agatgaatta gaaaatactc gcagtagtgt aagattgctt tttgcaccat atacacttga
     4561 ttttttaaag cagagtggaa gagttccagt tgcaactgct ttgataggaa atatgttaaa
     4621 tataaagcct atatttttct ttgataatgg ggaagctaag ttggtaaata aggttagagg
     4681 aataaagaat atagcaagta aattggtcga tataatttta gaaatgaatg aagggtcttt
     4741 agaaggaaaa atcgtcacaa taggttgtgg agataattta cacgattgtg aaatattaaa
     4801 agatgaagta aataaaagaa taaaagcaag aagagtatta tttactcgag gaggagtttc
     4861 tatttgctct catacagggc cagatatatt ggctataagt tgttctaatt agtagtaata
     4921 taaggttttt gcatatatat gtgaagataa ttttatattg ttaatttata gtatttttga
     4981 taatatagta aatagagtga tatacgtgtt ttttaataag aggaggacaa gcattaatgt
     5041 ttgaacataa aatatttaaa atggattttg caggaagaga actttctgta gaaataggaa
     5101 agatttgtga aatggctagt ggtagttgta tagttcgata cagtgatagt atggtaatgg
     5161 taaatacaac taaatcagcc aaacctagag acggaataga cttttttcct ttaagtgtgg
     5221 attatgaaga aaaattatac tctgtaggta agatacctgg aggtttttta aagagagaag
     5281 gcaagccttc agagaaagct atacttacat caagattgat agatagacca ataagacctt
     5341 tattcccaaa aggatttaga aatgatgttc aggtagttgc aacagtttta tcagtagacc
     5401 aagattgtac accagatata gtagcaatga taggttcttc aatagccctt tctatatcag
     5461 acataccatt taatggacca acaggttcag tatgtgttgg ccttgtagat ggtgcatttg
     5521 ttgtaaatcc aaacgcagag caaagagaaa aaagttcaat gcatctagtt gtttcaggta
     5581 caaaggaagc aataatgatg gttgaagccg gagctgatga agttccagac gaggtaatgc
     5641 ttgatgctat tttatttgct caccaagaaa taaaaaaaat agttgagttt atagaaggta
     5701 tagttgcaga agttggaaaa gaaaaaatgc ctgttgaatt ataccatgca ggagaagaaa
     5761 taactcaatt ggttcgcgaa tttgcaactg ataagatgaa aaaagcagtt cagacttttg
     5821 aaaagttaga gagaatggaa aatatggata gagttaaaga agaaacttta gctcactttg
     5881 aagaaacttt agaagatttt gaagattttg ttggagatat agaagaagta ttacaagata
     5941 taataaaaga agaagtaaga aaacttatag tacatgaaaa tgtaagacca gataatagaa
     6001 aacttgaaga aataagacct atatggtgtg aaactggcat gatacctaga gctcatggtt
     6061 cagccatatt tactagagga caaactcaag tacttaatgt tgctacttta ggtgctttag
     6121 gagatgttca aaaactagat gggttagatg aagaagaaaa caagagatat atgcatcatt
     6181 ataatttccc tgcatatagt gttggagaag ctagaccatc aagaggacca ggaagaagag
     6241 aaataggaca tggtgcttta gcagaaagag ctttattacc agtaatacca tctcaagaag
     6301 aatttcctta tgctattaga ttagtttctg aagtattaag ttcaaatggt tctacatctc
     6361 aagcaagtgt atgtggctca acattatctt tacttgatgc aggtgtacct ataaaagata
     6421 tggttgcagg tatagcaatg ggacttataa agcatgatgg taaggttgca gtgctttcag
     6481 atatacaagg tatggaagac catttaggcg atatggactt taaagtagct ggaacagagt
     6541 atggtataac agcaatacaa atggatataa aaattgatgg tatagataaa gaaattctac
     6601 aacgtgcttt aaaacaagct aaagagggta gaatccatat actaggagag atgagaaaaa
     6661 ctatatctca gccaaaacca gaactttcac catatgcacc taagattgtt aaaatgcaaa
     6721 taaatcctga caagataaaa gatgtaatag gacctggtgg aaagataata actaagataa
     6781 tagacgaaac tggagttaag atagatattg aacaaactgg ggaagtattt atatcaggta
     6841 ttgagattga tatgattaag aaagctcaag aacttataaa taatatagta gttgaaccag
     6901 aagtaggaaa aacttataaa ggtaaggtaa gtagaataat gaactttgga gcatttgttg
     6961 agatacttcc aggaaaagaa ggattacttc atatatctca tatagctcat gaaagagttg
     7021 ccaaagttga agatgtattg aatatagggg atgaagttga agttaaagtt acagagattg
     7081 atgaaaaagg aagagttaat ttatcaagaa aagttctttt accaaaacca gaacataaaa
     7141 ataaataact tattatataa ttaaaagcaa agtcttagga ttttgctttt ttaaatacaa
     7201 aaaagtagat aattttaaaa tgatagttat ggatggctta tagttctttt tctgtcaggc
     7261 tttactctta taaagaagct atttaaaagc tgattaatag agagctttat tgatatatat
     7321 agaatcactt aagttatatt tagtgcataa acagagctta tttttaatag tattaaataa
     7381 gaaacaattt gtacataatt agggggagtt ttaatgataa tgatggtact taataagagt
     7441 aagctcaaaa aaatcataat actaatttta gtagtgttat tagtattatc aggaggggta
     7501 atggtattaa agttatttaa caacaagcca gtatttaatt tatttaatgg tgtagattta
     7561 ccatatgaaa gaggtacaaa ggataaaagt ggatatgttg cattaacctg taatatagac
     7621 cttggatggg aaacagagta cgtagaatcc attttagaaa cacttaaaaa agaaaatgta
     7681 aagattacat ttaatgtaac tggaaaatgg gcagaaaaga ataaggatga attattaaag
     7741 ataaaaaaac aaggacatga aataggtaat catggataca aacatttaga ttattctaca
     7801 ttatcatatg aagacaatta tgagcaaata gagacctcta aaaagataat tgaagaaatt
     7861 ataggtgaaa aaactaaatt ttttcaagca ccagcaggtt cttttggtcc agaaacagta
     7921 aaggctgcta aagcattagg gtatacttct atcaaatggg atgccgatac tatagattgg
     7981 aaatacaaag accaaccaga ggtaatcatt gatagaatga agaaaaaaga cattaaagat
     8041 agtagtataa ttttaatgca tccaaccaac gcaacgacaa aatgtataga tgatattata
     8101 gctattgtaa gagaaaaagg actaaaacca ggaaaactta gtgatgtatt taagtagaca
     8161 aagtataaat atttggttaa gattgtataa gttgtagttg aattaattaa aagactgact
     8221 tataatgtaa tacatataaa aaataaatat aattaaaaca tagtgttttc aataatccaa
     8281 tatgaaacaa agaataaatt gttaggagaa tgtaatgtat aagacaaaaa tactggaaaa
     8341 tgggcttaca ataattggtg aagaaatacc atatctaaag tcaataacat taggtatttg
     8401 gataaatgca ggctctagga tagaagaagc acaggtgagt ggaacttctc attttataga
     8461 gcatatgatg tttaaaggaa ccaaaaacag aacatcaaaa gagattgcta gttcaataga
     8521 taatttgggt ggtcaaataa atgcatttac aagtaaagaa tgtacatgtt attatgtaaa
     8581 actaatagat gagcatatag atacaggaat tgatgtattg agtgatatga tactaaattc
     8641 taaatttgat aaaaatgata tagataagga aagacttata atattggaag aacttaagat
     8701 gtatgaagac tctccagatg acttatctta tgatttatta gtggaaaata tatatgctaa
     8761 tgatggatta ggaatgaata taattgggac aaaagaatct ctatacaata taactagaga
     8821 atccatgtta gaatacttaa ataagtatta tattccaaat aacgctgtta tttctatagc
     8881 tggaaacttt aactttgatg atatggtgga gaaaatcaaa tcaaaatttg gacactggga
     8941 aaagaaaaat ttaagtatag acataagtga ggctaagttt aatccttgct ttatatcaaa
     9001 aaataaagat actgaacagg tgaacttagc tatgtgccta aaaggtattc cttttgaaaa
     9061 tgatgaagaa gtctattcaa tggcagtggt aaataatatt ttcggtggaa gtataagctc
     9121 aaggcttttt cagaaaataa gggaagaaaa aggtttagta tattcaatat actcatcaca
     9181 gacattatat aggaaatgtg gtgaattagg tatatttgca agcatgagta caaaaaattt
     9241 acaagatgta tataatttaa taaagaaaga aattgaaaat ataagagaaa actatcttac
     9301 agaaaaagaa atatctgaaa gcaaggaaca gttaaaagga aattatatat tggatttaga
     9361 aagtactagc agtagaatga tgtctactgg taaatctatg ttacttagta aaaaagtaaa
     9421 aactacagat gaaatacttg aatgtataaa taatgttaat attaattcaa taaagaaggt
     9481 tgttgataag gtattcaata tcgaaaatat tggtacatgt atagttggaa gagatgtaga
     9541 aaagattcta cacttggatt aatattgaaa aaagtaaatc tctggaggta taaaatatga
     9601 atttatctga aatagcaggt aaggaaatag ttaacttggt cacaggagaa agattggggg
     9661 tcattggaga atgtgacctt atactagatg aaactacagg cggtatatta gcgcttctaa
     9721 ttccaaaaga aaaaggattt tttgccagaa gaaaagataa gtcattttta gaagtaccat
     9781 ggagaaatgt aaaaaaaata ggtaatgaca tgataattat agaatatgag ggatatattt
     9841 aggaggaaaa aatgagtatt ttagtgcaaa agtttggtgg gacatcagta gaatcatatg
     9901 aaaaaatgaa tgaagtatgt aagatagtaa aagcatacaa aaaaaatgat gaagaattac
     9961 aattagtatt agtagtttca gcaatgggaa gaaaaggagc tccatatgct acagatacac
    10021 ttataaattt gtgtagtgca gtaaatgatg agccaagtaa aagagaactt gatttaataa
    10081 tgtcttgtgg agaaataata tcaggaacaa ttcttgctaa tttattgaat gcacagggga
    10141 tagagtctgt tttctttact ggtcagcaag caggtataat tacaagtgat gaatattcta
    10201 atgcaaagat aaagtatata aatcctaaaa aggtaaaaag agctttagat gatggtaagg
    10261 ttgtagttat agctgggttc cagggtgtaa cagatgatgg agaaataact actcttggaa
    10321 gaggcggaag cgatacatca gcagttgcta ttggtaaagc tttagaatgt gaaacagttg
    10381 aaatttacac tgatgtggat ggtataatga ctgcagaccc tagagtagaa ccaaacgcta
    10441 aagtattgag ttttatagac tatgaggaag tattccaaat ggctgacaaa ggtgcaaaag
    10501 taatacatcc aagagcagta cagttggcta aaagtggaaa tataacttta gccataaaga
    10561 atacaatgaa tccaactttt gaaggtacaa aaataggttc tttatgtaga cacttagaag
    10621 acaatataga atatgaacaa gaaagagatt ttaaggttgc tgttgcaaat aaagatagcg
    10681 tagcacaagt taagattaag tcagcagaag aagtgtttac agaagtatta aatgagatag
    10741 aaaagaaact tataactata gatatgataa atttctttat atcagaaaaa gcatttgttg
    10801 tagaagatgc tgatataaaa tcattaaagg aaatactaga taaatttgaa ttagattatg
    10861 aagtaaatag agactgtgct aaggtaacat tgatatgttc aagaattgct gatgaaatgt
    10921 ctggtatcat gtcaaaggta gttagaggat tatcaaaagc aggggtatct cttttacaaa
    10981 catcagactc aaatatgact atatcttgtt tagttagtga agaagatatg catacagcag
    11041 tacatgctat acatcaacaa ttttatttaa aataaactgt ataatacaat tattttttaa
    11101 tcaaatttaa gaatttcata tatatcttaa tatatttgat ttatttggta aaactaaatt
    11161 aaatataatt ttgataggag tttttttatg aaagattata gagaagataa tgaaagattt
    11221 gataaagata attgtagtga agaatctagt tgtgaagaga gagaatgtat aaagcaattt
    11281 ggtaccaatg aaatgccacc tcaacctcct aaagatattc aatgtataac tataattgga
    11341 gaaattgagg gacattttat aggaaatcct caaaaaaaag ctacaaagta cgagcatata
    11401 attccaatgc tatactcaat tgaggaaagt aatgatgtta aaggagtgtt agttgtttta
    11461 aacactgttg gaggagatat tgaagcaggt ttagctattg cagaactttt aaacagtaca
    11521 tctaaaaaag tagttactct tgttctagga ggaagtcata gtataggtgt tcctcttgct
    11581 acagcaggag attactcatt tatagcacca acagcaacca tgattataca tccagtgcga
    11641 actactggtc ttgtgattgg tataaatgag acttttgaat attttaaaaa gatgcaagat
    11701 agaataattc aatttataat aagaacatca aatatcaaaa aagatgtact tgaaaaactt
    11761 atgcatgaaa aagatgaact tgtaagtgat gttggtagtg tattaatagg aaaagaagct
    11821 gtggattatg gtcttataga tgaagttgga ggactaaaag aagcacttaa aaaattaaga
    11881 gagcttataa aagaatctga ggaagaaaaa aataatgatt aaaatttgtt taaataataa
    11941 aatttatgat ataatgatgt aataaagtag gagtgttagt gttaaggcat tagcactttt
    12001 tgctgtgaag gggtaaaact tgctaaaaat aaggagtgat attaatggcc acgaaaaaga
    12061 agaaaaaaaa gaaggtaaat accttaagtt ttaatgcaga atatcataat ttaataacaa
    12121 tatttatagg tgtattttta ttatatagtt taaattctaa ttctatggga tggatacctg
    12181 tgttaatgca aaatcttttt aagggactat ttggagggct ttcaatagca ataccattta
    12241 tagtaattat aacaggactt ttaggatttt ttgatggaaa tgaatatata tataggctaa
    12301 gaaagactaa actatactac ataattattt tatttatatt tgtattttat ggattattaa
    12361 atgcaggaac tcttcctgta gatagcccac taaaaggtaa catgtttgat gatgttatga
    12421 aattgggtgt aagtggacaa ggtagtggtt tgatagcaac aactattgcg tattatatga
    12481 gtaaaatatt tggtatagca ggtggatggt taataagtat cttcgcactt atactttctg
    12541 taatgtttat atttaatatt tctataaaag atttggtgtc aaatgcaaaa tcaaaatcta
    12601 aagcatctaa agacagcaat ttaacgttta aagataaaat tgcaaatatg aaaaaatctg
    12661 caatagatat gatgactgat gaagtagatg atactactat aaataaaaaa ccaggtttct
    12721 ttaaagggtt aatgtcaaaa ggtcttaata atgatgatga tgaagatgaa tattttgaag
    12781 aagaaaatag tgatggtgta gatgacaaaa ctataaaaat agttggattt aataaggcag
    12841 aagatgagta tttagaaata ttagaaggaa ctcaaagtat gccagagtta gatgttttaa
    12901 aagaattaca aaaagctacc aatgaaaatc cagttgtaga tactaaagca gaaaaaaaag
    12961 ttgatatagc taaacctaat ttaaatatag aaaaaactca acctatgagt attgtagcag
    13021 agccagttaa tgaggattat tcaaactata aaaagcctag cattgagctt ttaaataaag
    13081 taaataagaa gtctgatgaa aatggtaaaa agaaagtgtt gaaaaatgct tctcttttag
    13141 aaaagacact atcagatttt ggagtggaag caaaaattaa tcaagttaca gtcggaccta
    13201 ctataacaag atatgaaata caaccaagtc caggagtcaa ggtaagtaaa attgtaaatt
    13261 taactgatga tatagcttta agtttagcag ctaaaagtat aagaattgaa gccccaattc
    13321 ctggtaaaag tgcaattgga atagaagttc caaatgaaga agctcaaatg gttggtgtga
    13381 gagaagttat agaaagtgaa gaatttaata attttaactc tcctcttgca atgggacttg
    13441 gaaaagacgt agcaggaaaa attataattg gagatatagg taagatgcca cacttactaa
    13501 tagctggttc tacaggttca ggaaagagtg tgtgtgtaaa tacattaata agtagtattt
    13561 tatataaggc aaatcctgat gaagtaaaat tactattaat agacccaaaa gtagttgaac
    13621 ttgcaaatta taatggaata ccacatctat tgataccagt agttactgac cctaaaaaag
    13681 ctgcaaatgc tttaaattgg gcagttacag agatgaatag aaggtacaaa ttatttgcag
    13741 atgctcaagt aaaagatgta acaagttata atgagaaagc ggaagaaaaa cttcctaaaa
    13801 tagtaataat aatagatgag ttagcagatt taatgatggc aagtgcaaat gatgtagaag
    13861 attatatttg tagattagct caaatggcaa gagctgctgg aatgcacttg attgtagcaa
    13921 ctcaaagacc atctgttgac gttataacag gggtaataaa ggctaatata ccatctagaa
    13981 tagcatttgc agtatcatct caaactgatt caagaacaat ccttgatatg ggtggtgcag
    14041 agaagcttct aggtaaaggt gatatgttat tctatccact tggtgcagca aaaccagtta
    14101 gacttcaagg ggcattcata tcagagagtg agtcggaaaa agtaatcgat tttgtaaaaa
    14161 gtcaagttaa agatggaata aaatatgaag aagatataat tgaaactata tctaaggtta
    14221 atacttcaaa gggtagtgat gaggatgagt ttttgagtga agcgatagaa tttgtcgtgg
    14281 aaagtggtca agcatctgcc tctatgctac agagaagatt taaaatagga ttcaatagag
    14341 cagctagact tatagattct atggaagaaa gaggaataat tggagcaagt gagggaagta
    14401 aaccgagaaa ggtattaata agcaaacagg atttgcagaa tttagaaggt gaatagaatt
    14461 gtcagttata aaaatagaaa aagcacttaa gctagataaa gtaatatttg tagatgtgag
    14521 aactgaagga gaatatgaag aagaccatat attgaatgca atcaatatgc ctctttttaa
    14581 aaataatgaa cataatgaag ttggaacaat ttataagatg cagggaaaac atgaagcaat
    14641 acaaaaaggg tttgactatg tatcgtataa attaaaggat atatatttac aagcagcaga
    14701 acttgcatta aattatgata atattgtcat atattgtgca agaggcggaa tgagaagtgg
    14761 cagtatagta aatttattat catcattagg tgtaaatgta tatcaacttg aaggtggata
    14821 taaggcttat agaaattttg tattagagta tctaaggcat gtaatggata caaaaaactt
    14881 tgtatctgtt catggattga ctggtacagg aaagactgat ttgttacatt tattagatga
    14941 aaaaggaata gacgtactgg atttagaagg catagctaaa aacagtggtt ctacctttgg
    15001 ttttataact tttgataaaa agccaccatc tcaaaagaac tttgaaacaa aactatttga
    15061 aagtatattt ttttcgaaag agaattatat atttgtcgag agtgaaagca aacgagttgg
    15121 aagtgttaca gttccaaatg aaattttcga ggcaatgaca cgagaaggac atcatatatt
    15181 attagaatgt gatattgaaa atagagtcga tagactttgt agagattata tttatgataa
    15241 agatgaaggt aatatattga ttttaaaaga atgtataaac aagtttagaa aaagattggg
    15301 taataaagta gtagatgatt atattgattt attagaatca ggtgaatata aagaacttgt
    15361 aaaaagatat cttttagaat actacgaccc actttatatg cattcagtag agaaatataa
    15421 gtatagtaag attataaatt ttaatgatac acaaaaagct ttagaagatg ttatagactt
    15481 atatgagagt atattggaag gagaaagtga atgttaaaaa tagcattgga atcattagga
    15541 tgctcaaaaa atttagtaga tgcagaaata atgatgggaa ttttaaataa caaaggctat
    15601 aaattaattg gagattttga agaagctgat gtaattatag taaatacatg tgggtttata
    15661 gagtcagcta aacaagaatc tatagatacg ataataaact ttgcagagtt aaaaaaaact
    15721 ggcaatttaa agttgttgat agtaacaggg tgtctagccc aaagatattc tgaagaatta
    15781 aaaactgaaa ttcctgaaat agatgctata gtaggaacag gaagctatca aaatatagat
    15841 aaaatactta aagaattaag tgaaatgcat caaattgtaa gccttaatga tatagagttt
    15901 gtatttaatg aagatttacc aagatatata tctacaccta gctatatggc ctatttaaaa
    15961 attggagaag gatgctccaa taattgtact tattgtataa taccaaaact aagaggtaaa
    16021 tatagaagta gaaaatttga agatataatt aaagaagcta agaaattagc tgaatctgga
    16081 gtaaaagaac ttgtggttat agcacaggat acgacaaagt acggttttga tttatatgga
    16141 aaagaaagat tatcagaact tttagaagaa cttgcaaaaa tagatggatt taagtggata
    16201 agggttatgt attcatatcc agaatctata acagaagaat tgatacaagt tataaagaaa
    16261 tatgataata tatgtagtta ctttgatatg ccaatacagc atgcaagtaa caatatttta
    16321 aaattaatga atagaaaaac tactaaagaa gatatattaa ataaaatcaa tctgataaga
    16381 agtaatatac cagatgctat acttagaact acaataatag tagggtttcc tggtgaaaca
    16441 gaagatgact tcaaacaact tgtggacttt gttgaagagg ttaaatttga tagacttggt
    16501 gcatttgcat attcaagaga agaagataca ccagcagata gattgccaaa ccatatagat
    16561 gaagaagtaa aaatacaaag aagagatact ttaatgatga ttcaacaaaa aatatctgaa
    16621 gaacttaatg acaaaaagat aggaaaaact tatgaggtgt taatagaaga acagatagaa
    16681 gataatgtat atacaggaag aacacaaggt gatgcagaag aaattgacag tatagtgtat
    16741 gtaaaaagtg tagacaatct tgaagtagga gaatttgtaa gtgttcaaat aaatgatgca
    16801 atggaatacg atttaatggg agatgtttta tatgaacttg cctaacaagt taactttgtt
    16861 tagaatattt ttaataccag tatttgtttt aattatgttg ctcaatatac caaataaatt
    16921 tttaatagct tgtattattt ttgtaatagc ttcaattact gatgctttag atggaaaaat
    16981 agctagaaaa tacaatctag tcactgactt tggaaaattt atggacccat tagcagataa
    17041 gttattggtt atttcagcac ttacatgtat gatagaagac catcttgtaa gtagttggat
    17101 ggtaattata atagtggcta gagagcttac agttagcata ttaagagcta tagctgctgc
    17161 tgatggaaaa gtaattgctg ctggaaacag tggaaaactt aaaacgataa ctcaaatggt
    17221 atctatagtg tttttattgt taggtgctca gtttgaaaat gtattgatat taaatattgg
    17281 tgaaattctc attcttatag ctacactact tacattatat tctggatggg aatatctata
    17341 taaaaataaa gagcttttta tgtcttctaa gtaaaaaatt atgctttaat aaataaaaac
    17401 taatgattaa taaataaaaa ataacaactt aaaattttaa aaatgtaaaa aagggtatac
    17461 tattatagta tacctctttt cattttaaga atattttctt ttgtgtatat aattattaat
    17521 aatggtttat aaataaaatg taatgaataa aaatataatc attagtagcg tttttaaatt
    17581 gactaggttt gatttatgtt atataattaa tatataacaa gagaacaaat gtttgtagat
    17641 aaatgaaggg atggtataga gatgagtgta gatcaagaaa aattaaaagc gttgaatgaa
    17701 gctttaggta aaattgaaaa agattttggt aaaggttcag taatgaaatt gggagaagca
    17761 acatctatgt ctatagatgt tatatcaaca ggagcgattg gtttagacat agctattggt
    17821 ataggaggtc tacctagagg gagaatagtt gaagtatatg gtccagaatc ttctggtaag
    17881 actactgttg cgcttagttg tgtagcatca gctcaaaaag atggaggaat agctgcattt
    17941 atagatgcag aacatgcact tgacccagta tatgcaaaag ctttgggtgt ggatgttgat
    18001 aacctaataa tatctcaacc agatacaggt gaacaggctt tagagatagc agaggcattg
    18061 ataagaagtg gagcgataga tataatagta atagactcag tagcagcatt agttccaaag
    18121 gctgaaatag atggagatat gggtgattct catgtaggtt tacaagctag acttatgtca
    18181 caagcactta gaaagttaac tggttcaatt aaaaaatcaa attgtgttgc tatatttata
    18241 aaccagttaa gagagaaagt aggaataatg tttggaaacc cagaaactac tactggagga
    18301 cgtgcactaa aattctattc atcagttaga ttggatgtta gaaaaataga tacaataaaa
    18361 caaggtgata aagttatagg tagtagaact agagttaaag ttgttaaaaa caaagtagca
    18421 ccaccattta agcaagctga atttgatata atgtatggag aagggatttc aaaaattgga
    18481 gaccttttag atatagctgc tgatgtagat atagttaaaa aatcaggttc atggtatagt
    18541 tacaatgata ctaaacttgg acaaggaaga gaaaatgtta aaaaattctt ggaagataat
    18601 ttagatttaa ctactgaaat agatgagaaa gttagagcat tttacaattt aaatgaagaa
    18661 catgaagaat caggtacttc agtatcaaaa gaaattgtag aagaataagt aaaaatacaa
    18721 aaaaataact agtaattaaa gacatgccac gctccctatt agcttgacac aatgttgaaa
    18781 aaattataaa attaagtgag gataaaatat ctaaatttaa ttttaattat taggaatatt
    18841 ttttaatcat agtgatgaca ttttgggatt attaacgaag gaggtggatg tcatagatag
    18901 tgtagtaatg attgtaatag gtgcagctgt tggtattata gctggatatt ttgttagaaa
    18961 aaatatatct gaagcaaaaa ttggacaagc tgaaaacttg gccaaagaaa taatagataa
    19021 agcacaccac gactcagaaa cagtacaaaa agaaaaatta ctagaagcta aagaagagat
    19081 ccataagtgg agaacagaag ctgaaagaga aaacagagaa agaagaacag aagtacaaaa
    19141 gtatgaaaaa agagtagtac aaaaagaaga agtcttagat agaaaattac aaaatttaga
    19201 atctaaagaa gtaaacctaa gtgaaaaatt aaaggtagtg gaaaagaaag aagaagaagt
    19261 tgaagtaata aaaactcaac agttagaaaa attagaaagt atatcaggaa ttacttctga
    19321 taaggccaaa gaaatcatct taaccaatgc ggagagagat gtaagacgtg aaatgtctat
    19381 aatgataaaa gagatagaaa gtcaagctaa agaagaagct gataagaaat caagagaaat
    19441 tataggatat gcaattcaaa aatgtgcagc agatcacgta gccgaaacta ctgtaacagt
    19501 agtaagcttg cctaatgatg aaatgaaagg tagaataata ggtagggaag gtagaaatat
    19561 aaggacttta gaaaccttaa caggtataga ccttataata gatgacactc cagaagccgt
    19621 aattttatca ggatttgatc caataagaag agaaattgca agaattgctc tagaaaaatt
    19681 aatagcagat ggaagaatac atccagctag aattgaagaa atggttgaaa aggcgagaaa
    19741 agaagttgac aatattataa aagaatatgg tgaacaagct gcatttgaaa ctagtgtaca
    19801 tgggattcat ccggaattaa taagattatt aggtagactt aactatagaa ctagttatgg
    19861 acaaaatgta cttaaacatt ctatagaagt tgctcatata gctggtataa tggctgctga
    19921 aataggagca gatattagat tggctaagag ggcaggttta ttacatgata taggtaaggc
    19981 tgtagaccat gaaatggaag gtacacatgt tgaaataggt atggatttac ttagacgtta
    20041 taaagagtct aaagaagtta tacatgccat gagtactcat catggagatt acgagcctca
    20101 aacagtagag gctgtattag ttacagcagc agatgcaata tcagctgcta gacctggtgc
    20161 gagaagagaa actttagaag catatataaa gagacttgaa aaattagaag aaatagctaa
    20221 ttcatatgaa ggtgtagaaa aatcatttgc tatacaagct ggtagagaaa taagaataat
    20281 ggtaaaacca gaagctataa atgatgaaga aatacatcta ttggctagag atatgactaa
    20341 gaaaatagag gatgaacttg aatatcctgg acaaataaaa gtaagcataa taagagaaac
    20401 aagagctata gagtatgcga agtaaaagaa ataatatcta aataataaga aaatattttt
    20461 agaaatttaa atttgccaca agatatgata atatatcttg tggcttttaa attgtttaag
    20521 tttaatttta tataatgcaa aaataatcta agtgctaaaa gtgctactta caaaagatta
    20581 ataaaataaa gctttatata tgtattattt atataattat ccaagtttgt ttgatataat
    20641 gaagttgtaa aatcaatact ttactacaaa ataaatagta aatactacag taaaatctaa
    20701 aaataggata taatagtatt aatataagaa gattataaat aaaacctgct aatgaaaata
    20761 gattattttt agcaggtttt taaatttttt ataataaatc ttatttttag tcaacaagat
    20821 ttattttt
//
LOCUS       DAEPUT010000072        20684 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.074, whole genome shotgun sequence.
ACCESSION   DAEPUT010000072 DAEPUT010000000
VERSION     DAEPUT010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20684
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.074"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(25..729)
                     /locus_tag="KRL22_002841"
     CDS             complement(25..729)
                     /locus_tag="KRL22_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1273292.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSTCVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFKK"
     gene            894..1619
                     /locus_tag="KRL22_002842"
     CDS             894..1619
                     /locus_tag="KRL22_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1273293.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            1679..3271
                     /gene="hcp"
                     /locus_tag="KRL22_002843"
                     /gene_synonym="priS"
     CDS             1679..3271
                     /gene="hcp"
                     /locus_tag="KRL22_002843"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBH1273294.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            3643..4548
                     /locus_tag="KRL22_002844"
     CDS             3643..4548
                     /locus_tag="KRL22_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH1273295.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFRLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            4672..5625
                     /gene="msrA"
                     /locus_tag="KRL22_002845"
     CDS             4672..5625
                     /gene="msrA"
                     /locus_tag="KRL22_002845"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBH1273296.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            5778..6908
                     /locus_tag="KRL22_002846"
     CDS             5778..6908
                     /locus_tag="KRL22_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273297.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(7025..7993)
                     /locus_tag="KRL22_002847"
     CDS             complement(7025..7993)
                     /locus_tag="KRL22_002847"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBH1273298.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            8328..8516
                     /locus_tag="KRL22_002848"
     CDS             8328..8516
                     /locus_tag="KRL22_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273299.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
     gene            8776..9975
                     /locus_tag="KRL22_002849"
     CDS             8776..9975
                     /locus_tag="KRL22_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HBH1273300.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            10027..10530
                     /locus_tag="KRL22_002850"
     CDS             10027..10530
                     /locus_tag="KRL22_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1273301.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVVHS"
     gene            10637..10954
                     /locus_tag="KRL22_002851"
     CDS             10637..10954
                     /locus_tag="KRL22_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273302.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            11112..12071
                     /locus_tag="KRL22_002852"
     CDS             11112..12071
                     /locus_tag="KRL22_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH1273303.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKLLIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            12186..12971
                     /locus_tag="KRL22_002853"
     CDS             12186..12971
                     /locus_tag="KRL22_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273304.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            13263..14582
                     /locus_tag="KRL22_002854"
     CDS             13263..14582
                     /locus_tag="KRL22_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1273305.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(14657..15085)
                     /locus_tag="KRL22_002855"
     CDS             complement(14657..15085)
                     /locus_tag="KRL22_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273306.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(15176..16552)
                     /gene="hydG"
                     /locus_tag="KRL22_002856"
     CDS             complement(15176..16552)
                     /gene="hydG"
                     /locus_tag="KRL22_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HBH1273307.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIREEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(16553..17638)
                     /gene="hydE"
                     /locus_tag="KRL22_002857"
     CDS             complement(16553..17638)
                     /gene="hydE"
                     /locus_tag="KRL22_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HBH1273308.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(17674..18882)
                     /gene="hydF"
                     /locus_tag="KRL22_002858"
     CDS             complement(17674..18882)
                     /gene="hydF"
                     /locus_tag="KRL22_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HBH1273309.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            complement(18897..19148)
                     /locus_tag="KRL22_002859"
     CDS             complement(18897..19148)
                     /locus_tag="KRL22_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HBH1273310.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(19529..20569)
                     /locus_tag="KRL22_002860"
     CDS             complement(19529..20569)
                     /locus_tag="KRL22_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBH1273311.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT         7750 a         2499 c         3273 g         7162 t
ORIGIN      
        1 aataaatatg tttaaatatc tattttattt tttaaaataa aagatttcaa atttattttt
       61 gttaaaagat aacaagcctt catctcgcat cttgccaagc tctcttgaca tagaacttct
      121 gtcaacacat aaaaaatcag ccatttcatt tcttgaaaag ggaattgtaa actggtggct
      181 acctgtttgt tctatctgtt ttgaaaaata cataagcaat ttctcgcgag ttgttttacg
      241 agaaagtaat tctattttat tgtgaagtaa aatgtttttt tcagctatta attgtagcat
      301 attttcaaca agcctattat gaaatacaca tgtagatgaa caaataccag ttacactttt
      361 aaactttata aataaaactt cgcaagaaga tgttgtggtt actgtaacat tacttttatg
      421 tagtctagta catgcgaata cctctccaaa taaatctcca ggcaagagtt cagctacaat
      481 attcctattc ccttcgatat cttcctttat tatatgagca cttcctttaa gcataattcc
      541 aatagaagta acttcacttc caacagagaa tattatacta tcttttgggt aagttttatc
      601 tacaacacct aaacattcca acatttcttc aagttcatca cttttaattc cttcaaatag
      661 aggaattttt ttaagtaggt ctatatgctt ttctaaaaat tttttcaaat aatcacttcc
      721 ttgttgcata tgcaaccgat aatttgtttt cattgtacta tactaagttt ataaaagcaa
      781 ggggatataa aaatcctact acaagaaatt tgaaataaag aaatataggt attaaaaata
      841 aatatataag aaatcaatac tttaaattaa aaaaatttta tgaggtgata taaatgatga
      901 gaaaaataat taaaattgat gaggaaaagt gtaatggttg tggactatgt gttgaagctt
      961 gtcatgaaga agctatagga atggtaaatg gaaaagcaaa acttttaaga gatgactatt
     1021 gtgatgggct gggagattgt ctgccaactt gtccaacaaa tgcgatttca tttgagtata
     1081 gagaagcagc agaatatgat gaagctgcag taaaagcaaa tatggaagca aagaaagcac
     1141 aaaagaaaac tttagcatgt ggatgtccag gttctcagtc taagtcaata aatagagagg
     1201 tttcaaatag tacgtctata agcaatgata tagtagagat aaaaggttct caacttaatc
     1261 aatggccagt acaaataaaa ttagtaccaa ctaatgcatc atatttaaag aatgcaagtc
     1321 ttttaatagc agcagactgt acagcgtatg catatggaaa ttttcataat aaatttatga
     1381 aaaataaggt tacattaatc ggatgcccta aacttgatga agttgactat gctgaaaaac
     1441 ttacagagat tttaaaagaa aatgatatta aaaatatagt agtaacacgt atggaagttc
     1501 cttgctgtgg tggtatagta aatgctgtta agacagctct acaaaatagt ggaaaaatga
     1561 taccatggca aatagttact atatctgtag atggaaaaat tgtagatgga gaaatttaat
     1621 taagtgaatt atagaaaaat ataataaatt ttaataaata aaaagggagg aataaaaaat
     1681 ggaaaaaatg ttttgttttc aatgtgaaca aacagcagga ggtaaaggtt gtactataaa
     1741 tggtgtctgt ggtaaaaagg ggggtacagc taacttacaa gacgaactta caggagtgtt
     1801 gattggtctt tcaagagcaa ctattggaaa taagaataga ccaacaagtg aaacagataa
     1861 aattatgata gaggggctat tcactactat aacgaatgta agttttgatg atgaagctat
     1921 aaaaagacaa attgaaaaaa ctgaggtaga aaaaagtaaa cttgtaccta gatgttcaga
     1981 ttgttcaaca acttgtaata gaaatgataa ctatgatatg aaggatttat ggaatgataa
     2041 tgaagacata cgttcattaa aatcattaat cttatttgga ttaagaggta tggctgccta
     2101 tgcatatcat gcaatggtac ttggttatac agacaaagac gtaaatgaat ttttctatga
     2161 aggattaata gcagttggag gagacttgtc tattgacgaa cttttaggtc tagttatgaa
     2221 aactggagaa ataaacttaa aatgtatgga attgcttgat agagcaaata ctgaaactta
     2281 tggaacacca gaacctacac aggtatctat gaaaatcgag aaagggccat ttattgtagt
     2341 tacaggacat gacctttatg atttacacaa attattagaa caaacgaaag ataagggtat
     2401 aaatatatat actcatggtg agttattacc agcacatgca tatccaaaac taaaagaata
     2461 taaacatcta aaaggtaatt ttggtacagc atggcaaaac cagcaaaaag aatttgataa
     2521 tattcctgct ccaatattat ttacaacaaa ctgtttaatg cctgttaaag atagttatag
     2581 agatagagta tttactacag aagtagttgc ttatccaggt atggttcata ttgatgaaga
     2641 taaagatttt tctagtgtaa tagaaaaagc tcttgaactt ggaggatata gagaagatgt
     2701 tcatatgact ggtattaatg gaggagatac attaactact ggttttgcaa gaggtacagt
     2761 ttcatctgta caagataaag tagtagatgc tgtaaagagt ggagctataa gacacttttt
     2821 attggttgga ggttgtgatg gtgcaaaacc tggaagaaat tattacactg aatttgtaaa
     2881 acaagctcct aaagacactg ttatattgac acttgcatgt ggaaaatata gatttaatga
     2941 tttagacctt ggggatatag gtggcttacc tcgtttaatg gatatgggac aatgtaatga
     3001 tgcttatagt gcaattaaag tggcagtttc attggcaaat gcttttgaat gtggagtaaa
     3061 tgatttgcct cttagcatgg tactgtcatg gtatgagcag aaagctgttt gtatacttct
     3121 tacactactt catttaggta tcaaaaatat ctatatagga ccttctttac cagcattctt
     3181 atctaagaat gtattagata tattggttga taaatttgca ttgacaccta tatctactcc
     3241 tgaagaagat atgaagaaga ttttaggata aataaatata tctatactta aagatattta
     3301 tagttaaact atttttaagt atgccacaat taagataagg ggttaaactt aaaatttgat
     3361 taaaaaatca attttgagat gaccctttat ttattttttg taataattga aaaataaacc
     3421 tgctttcagt atattttttt taagaatctt tgtattaaat ttataatact tagatatata
     3481 atatcttata tattttattt taagtattaa aggtttgaat gtaacttaaa tattaaaaga
     3541 ggaacattgt aatatgtaac ttgcataaaa tatatatact atagtgaaat tattttgatt
     3601 aaaatttaaa atataaggtg ttttatgtgg gggtatatgt atatgaaaaa ttctaatttt
     3661 aatatattgg catttgatgg tggtggatta aaaggggcat tgagtatatc catacttgag
     3721 aggatagtaa aagagtatcc aaatctatta aacaatataa atatgtttgg aggtacatct
     3781 acagggagtc taattgcact agggcttgcg tatggtgtaa gccctaaaga gataaaagaa
     3841 ctttactcaa ttgaaaattc aaagtatatt tttaataaaa gttatgcaga aatactcaga
     3901 ccaaagtatg aaaacaaaaa cttaaaagaa gttttattaa gtatatttcc agaggaacta
     3961 gaattaaaag atttaaataa attagtaatg ataccaagtt tttatatagg aaatgaggaa
     4021 aatgcatgga aaccagtatt ttataacaat atgccaaatt cttttacaaa gactagcaaa
     4081 gttgtagatg tagcaatggc aagtagtgct gctccggtat tttttccaac atataatcgt
     4141 catgttgatg gaggaataat agcaactgac ccgagtttag cgtgtataat tcatgccatt
     4201 gacagtggat ttagacttaa gaatacaaga cttttttcaa tagggactgg atatgtatat
     4261 aacagtataa aggcagatac taccgaatgg ggagctattg actggataat taataaagaa
     4321 cccgatttac caattatatc tattacctta gaaggaaatt ctcaaatgag tcagttattt
     4381 tctcaaaaac ttcttggaga taattactat agattaaatc ctaagatgga aaaagatgta
     4441 gctatggatg attgtgatgc attagaatat ctaatgtctt taggagaaaa ttgtgatata
     4501 aaagatgctt ttggatggat aaagaaaaag agcttttata gaaattagat tcaatttgca
     4561 attgtatttt tacacatgat ttcattgagt aggtaaaaat aataaaatgc agattattaa
     4621 gttacttctt agggaataaa taaagtataa tttatttaag gagtgatgaa aatgataaaa
     4681 cttgctactt ttgcaggtgg atgtttttgg tgtatggtaa aaccttttga taagtatgat
     4741 ggagttatta aagtagtttc tggatataca ggtggtcatg ttgaaaaccc tacatatcaa
     4801 gaggtatgct caggaactac tggtcattta gaagcaattc aaataacata tgatgatgat
     4861 ataataagtt atgatgaact tctaaatatc ttctggaaac agattaatcc tacagatgat
     4921 ggtggacaat ttggtgatag gggaactcaa tataagactg ctatatttta tcatgatgaa
     4981 gaacaaaaaa atatagcttt agagtcaaga gaacatctgg aaaatagtaa aatatttgat
     5041 agtaaaatag tgactgatat aattccagca actaaattct acgaagcaga agaaaatcat
     5101 caggattatt ataagaaaag accattaaac tacaatatgt attataaagg gtctggaaga
     5161 tataattttg taaaaagcca ttgggatgga aacaatataa atagggaaga gttaaaaaag
     5221 actctaactc ctatacaatt tgaagtcact caaaatgata tgacagaagt accttttgaa
     5281 aatgaatatt atgacaataa caaagaggga atttatgttg atattgtaag tggagaagtg
     5341 ttattttctt caaaagataa atttgattct ggatgtgggt ggccaagttt ttcaaagcca
     5401 gttatagata aatctatcat tgagagaagt gatttctcac aaggtatgta cagagttgaa
     5461 gtaagaagtg ctaaaggaaa ttctcattta ggtcatgtat ttgatgatgg tccaaaagaa
     5521 cttggaggtt taagatattg tataaattct gcttctctta aatttatacc aagagaaaat
     5581 atggaagctt taggatatgg agaatattta aaactttttg agtaattagg aatatttatt
     5641 ataaacttat ctaaaaggtg aaaatataaa aaaatatttt caccttttgt ttttttgtca
     5701 ataatatgat aaattattaa ttgtaatctt atttatacca atagattaag aatttaattt
     5761 tgaaagagag aaaacaaatg aatttaaaag actttaatgg aaagagatta aaatcagcta
     5821 gaatttttag agcaaagacg atagaacagt tgtctaaaga aactaaaata aataaaaaag
     5881 atttaaaagc ttttgaggaa aataagtatg taccaaatat agaaaataca ttaaaattat
     5941 ctaatatatt aaattttcca aaagagtatt tttataaaaa tgaaaatata aatatcgttg
     6001 tagaggatag ccactttaac cctcaatcta aactacctag agtagaagag atttcttata
     6061 gagaaaaaat aattataata cataaaatat attcatttat ggagaattat attaagtttc
     6121 caaaagaaaa cttgccaaat agaaaagtaa tgtcagatat taatataaat gatatagaat
     6181 ctcttgcata taagactaga gagttttggg atttaaatag tactccaata gtaaatatgg
     6241 taagtttgtt agagtctaaa gggattataa tatcaggtat gaatgtagat agaaaagggg
     6301 caactatctt tactcaaaaa cagagaatta gtaaagaatc taaatatcta atatctctgg
     6361 gtaatgacaa aaagtcagca tcaattagaa attatacttt ggcatgtgag cttggatata
     6421 taatatcaag tgaattaaga ataccaagta agcaattttc agaagatgag tatgcctgtg
     6481 catttttatt gccaaaagag agttttttaa aagatttgac tcatccagaa gatttagatt
     6541 attatgtaga actaaagaaa aaatggattg tacctatatc tgctatgatt tttagagcat
     6601 ataatctaga aaagataaat tacaaaaaat acaattatct tatgaatgaa atggataaaa
     6661 aaggctggtt gatagaagaa ccactagaca aaatgaaagg ttcaagccca acgtatttaa
     6721 aaagagcagt tgaattattg atagaaaata aaataatgag tgtaaatagt atagtatcaa
     6781 gtttagagga atttggaata aatctttatc cagaagactt agaattattg atgggattga
     6841 aaaaaggatt gttatctcaa gaggtaaata aaaaaagtaa agttataaaa tttgatggta
     6901 aaaaataggt ttatatttta gtattaaaat taaaagcagg tacaaatgat ttaaacatta
     6961 acttagttaa aagtcttttc aataagtcat ttacctgctt ttagtgtaag aaagaatatt
     7021 gaatctaaag tgtttttgaa agtgcaatat attcccttaa aacagaacaa gatttattaa
     7081 attcgttttg ctcatattca gtcatattga tttcaataat ttcttcaata ccatcttttc
     7141 ctataacaca tggaacacct gcaaatacat ttctttcgtt atattgacct tctagtaatg
     7201 tagaaactgg aagaactttt ttctcattgt gtagtatagc ttttacaatt tctactaaag
     7261 cagtacctat accaaattct gtacaatctt taccatttat tatacttatt cctgtttttt
     7321 tatttttttc aactattgat ggtaagtcta aattgctata agtacttggg ttgtctttta
     7381 tcatgtctaa gattggttta ccaccaattg aaacatgaga ccaaggaacc atttgagaat
     7441 ctccatgttc acccatagaa taagcttgaa ttgattgttg agcgattcca gtttcttcag
     7501 ataaaatcct tctaagtctt gttgaatcta aagctgttcc agttccaatg actttgtttt
     7561 taggaaagcc agatttttcc caaatataat ttgtaactac atcaacagga ttagatatga
     7621 ctacaaatat accatcaaag ccagaatcaa ctatgggttt tactatagat tttatcattc
     7681 caatagttgg tcttagtaaa tctaatctag ttgtgttttg tctacgtaaa ggcccttctg
     7741 aagagtctgc aacacttatc actactatgt cagaatcttt acagtcagaa aaagttcctt
     7801 tttctatatg tactttatgt ggcagatatg aaactgcatc agctaaatct aaagcttgag
     7861 cttttgattt agattcatct atatcaatca taaagagttc atcacaaact ccttgagtta
     7921 ttaaactaaa tccacaatga gaaccaacat gccctgaacc tacaatagat atttttcttg
     7981 gctttattgc cattttaaat cactccccct aaaataacga tacattgaaa attatagatg
     8041 ttattaaaag ctgtttttgg atattttaat attctattat ttcagaaaat ttatttaata
     8101 tgattttata ctaaaatttt taaaaaagca atgttaatat actctctatt agtgaatatt
     8161 aaagtattat atgtatatta ataattatta aaatatgtaa tgtcactgat agttagaata
     8221 tttaagtgct aaaagatgtg tataaataat aatgatgtca gtttataatg atattaaatt
     8281 gagatatact gtttctctaa attaaaaaat aaaggagtaa atgtgttatg aattatcata
     8341 caaaagaaga attggtggaa gcactgagag tagtatcttc aagtattatt aattgtggaa
     8401 aaggacagaa gaaattttct gaggagacat ctcatcatac acgttttaag aatattatag
     8461 aagtaatgta tatttcaaaa tcattaataa tggatgaaat tagtaaaaga gattgaagct
     8521 tattttgcaa tttaacatgt tttaatatac attttattat ataagaaaat aagtaaacat
     8581 acatgttata aaatattgga ataatataca attataaatt tgttaacact aatatctata
     8641 tgttaaaata tagtagaaga tgttagtaaa taataggatg agttctattt taatacaatt
     8701 aaattaagct tagtttgaaa tttgtatcta aaaagtaaag taatctagaa ttaagaaaat
     8761 ggagatagaa ttataatgga aaagttatat tatacaaatc agtatataag agattttaca
     8821 gcagaaataa ttgaaataaa agaagtagaa aataagtatc atgttttatt agataagaca
     8881 gctttttttc ctggtggagg aggtcagttt ggagacctgg gaaaaataga gaatgatgat
     8941 gtaataaatg tgtatgaaga tggaaaaaaa atataccatg tattagataa aaaacctata
     9001 aagatacata aggtaaagtg tagtattgat tgggatagaa gagaagatgg aatgcatcaa
     9061 cattttggac aacatgtatt gtctggatgt ttttttaaaa cttttaatgc aaatacgaca
     9121 ggttttcatt tgggaaatga gtatagtaca gtagatatag aaggtaattt agaagaggat
     9181 aaaattagag agatagagtt gtttgccaat gaaattattc gtcaaaatat acaagtagag
     9241 acattacttc caacgaaaaa agaactaaaa aagatttggt taagacgtga tttgccaaat
     9301 actgatgaag agataagagt aataaaaata ggtgatttag atacgaatgc atgttgtgga
     9361 gtgcatccaa aatcaactgg tgaattgaga atgataaaaa taaagaaatg ggaaaaacat
     9421 aagtcaagta caagaataga gtttctagca ggtaaaaggg cagtggatga agtattgaag
     9481 agggatatat atttgactaa aatatgtaga tatttaagct gtagtgagga agatgctata
     9541 aatggtattg taaatctaaa tagtaaagtg gaagaggctt taattaaaaa aagaaggctt
     9601 gaagaagtag tatctacata tcaggtcaaa gaaatgattg aaaaagcaaa taaggttggc
     9661 aatatttcgg tcattaaaaa aatttatgat gatgaagatt tgaaatatgt aaataagata
     9721 gcaaataaaa ttgcagaata tgaaaatagt attgcattat tagctgttaa atttaatgat
     9781 aaaataaatt tagtttttgc atgttctaaa aatttaaaag atattaatat gggagtttta
     9841 ttaaaggatg caataagtct tatagatggc aagggtggtg gaagtaaagt attagctcaa
     9901 ggaggaggta agaataatgg aaatttagag gctacacttg attatgcatt tatgaagata
     9961 gaaaaaactc tataaatata ttatataaaa aaccttagta gataaaatag atatggagga
    10021 ataagtatgg agcaacaaaa ggactacata gagttatatg aaaatgaaga actaatagag
    10081 ataagagaag cacgtatgga tgatttggat acaatagcaa aatttaatta taatttggct
    10141 aaagaaactg aaggaaaaga acttgatatg gatgttttaa ctaaaggtgt aaaagcattg
    10201 ttattagatg agagaaaagg aaaatatcat gtatatacag tatttgataa agttgttgca
    10261 cagattatgt atacatatga gtggagtgat tggagaaatg gaaatttcct ttggattcag
    10321 agtgtatatg tagataagga atatagaaga aaaggtatct ttaattattt atttaattat
    10381 ataaaaaata tatgtgataa agatgaaaat atagttggaa tgagattata tgtagaaaaa
    10441 gaaaacataa atgcaaaagc aacatatgag tctttaaata tgtatgagtg tgattataat
    10501 atgtatgaat acgaagtagt acattcgtaa tataaatttg taatactgtt atactgatgt
    10561 tataaagtat tgattatatt gacgattata tgaaataaac tggatattat aattagaatt
    10621 tttagggggt ataaaaatgg gcgttttaaa aggaatgttt tatgtatttt tatttttaga
    10681 tttagtgtca atattctgtt tctttttcaa taaaggaaaa atagcatcta ataaaattgt
    10741 gtttaatgca ataggagtac ttacatttgt actttgtttt atgcttttta gttattatcc
    10801 taataataat cttattggaa aatttattgc ttctctattt tttatatttg gagttgcagg
    10861 agttatgttg aaagaaaaaa attttttata tgctagactt cttttaactg tagttatagt
    10921 tttttctaca ttaagattgt tcgttattca ataaaatgta tttgtatgaa aatttattaa
    10981 agtctacaca tttaagtgta ggcttttttg attttttgtt tgaaaattaa ggaattttta
    11041 aggaaatttt aaaatcgtct taaatattta ttgatatact taaaatatta atagcgaaag
    11101 gagacttatc agtgatagaa agtaaaaagt cagaaaaatt gttactgtca attatataca
    11161 taatattttt ggtatatatt ttaatgatta taagaataat tttatttaga gatgtaccaa
    11221 tttacgctat tttcaaggga acgtttagga atgtaaattt aattccattt tatacaatat
    11281 atcaatttat agtagatagt aatcttgact ttatgaaagc tactgtaaat attatagaaa
    11341 atataggtat atttattcct atgggaattt ttttacctat agtatgtaaa aatctaaata
    11401 aaaaaactat aattatagta attatacttg ttagcctagc atttgaatta acacaatata
    11461 tttttgctct tggaagtagt gatatagatg atgttatttt aaattcatta ggtggcataa
    11521 ttggaattaa tatttacata aacatgaata aattatttcc caatgatatt aacagattta
    11581 aggctataat aggtactagt ttagttttag gagttatagg attaggagtt atttctaaaa
    11641 attatcataa cttactaact tttaaattta gacctgatag aaaaatatca aaactattaa
    11701 ttgaagaaaa tagggaaata attaaagata taaataaaga tacagtagat atagttggga
    11761 catttgagag ctttaaaaaa ggaataataa ctattaaagc aggttctaat aacaaagtaa
    11821 agagaccaga gaatttaatt gattctgatg gaaatataag aatttattta aatgaaaata
    11881 caaaattagt atcttatata attaccaaag aatcaaaaat ggatatagtt aaatatgagg
    11941 aatttgatgt gaagaattta gatttattaa ggagatatga tactattaat gtttggattg
    12001 ataaagaaaa tcagccaaag gataaacatg gtattatggc tagtaaatta ttaattggat
    12061 tgtatgaata aaatattaaa caagaataaa agaataacaa atataaaaaa cgaaaaaact
    12121 atttctataa ttatttttac gttgtgcata aaataagaac attagtgaag gagtagagat
    12181 aaattatgga gataataaaa tatatcttgt acttttttat atattcattt ttaggatgga
    12241 cagtagaaag tataggatgt tctatagcaa gcaaaagaat aatcaacaga ggttttttaa
    12301 atggtccaat atgccctgtt tatggttttg gagcggtaat tgtgatatca ctattgggaa
    12361 gatttaataa tgtagtaata gtatttctat taggaatgat tttaactacg atactagaat
    12421 attttacagg atttatttta gaaaccttat ttcatgctaa atggtgggat tattctgaca
    12481 gaaaattcaa tataaagggt agagtatgtt taaaaaatgc aatatacttt ggtgtaatgt
    12541 ctgttttaat aataagattt atacatccat ttataaaata ttttgtaagt ataattccat
    12601 atagaatatt aatttcaatg gctataatta caacactttg gactatactt gatttgattg
    12661 ttactattat aacacttaaa aaattagata taaagttaaa cttattagac gatataatta
    12721 cagaccttaa tgatataaat gtgaaattgg ataaatttga tagaggagaa atacaagctt
    12781 tatttaaaac aataaataac gacgaattag aagttagaga aaaaataaac aaaataaata
    12841 gtaagttgga ccgtatagag tctaatatta ttttacaaaa aagagttata aaagcttttc
    12901 cacatataaa acataaaaaa caacaagagc aactagaaca ttttaaaaaa attattaatg
    12961 agaaaaggta attatacaat ttaatgaaga cgaatagaat aatggtattt ataagatgat
    13021 tttcagagga ctctataaaa atagaataga gtcctttatt ttttgaaaaa taatgtttat
    13081 ttgataaaaa taaaatatat tgtttctgaa taacaaatat tttgaaaatt ataaaaacat
    13141 atattgacaa tttgtgtcaa aaatactaac attaagtata taaagaattt tatatgagaa
    13201 tatctttata aatcgcaata attttaaaac ataaatttat ttaaagaggg gatgatttgc
    13261 caatgagcga gataactagt caaatgataa gtacagaaga aaaaaaatat gttgctaaaa
    13321 ctcaaaagat accttattat ccagtagcat ttaaatcagg tgatggtgca atgctatatg
    13381 attatgaagg taatgaatat gtagattttt tagcaagtgc aggctctgca aatgtaggtc
    13441 atggtaataa ggaaatctca caagcagtta aagaacaaat ggatgatata acacaatata
    13501 cacttgcata tttccatagt gatcctcctg taaaattagc tgagaagctt gtggaaatag
    13561 cccctggaga taatgataaa aaagtactat acagtgcaac tggttctgct tgtatagatg
    13621 ctgctataaa attagcaaga gggtatactg gaagaacaaa gataatatct atgtgtgaat
    13681 cttatcatgg aagtacttat ggagctatat ctatatctgc tttaagtaca aatatgagaa
    13741 gaaaaatggg tccattgtta ccagaagttt atcacttcca ttatcctgat aaaaatagaa
    13801 cagctaaaga atgtttagat gagatagaat atgcttttgc acactatcta ccagcagaag
    13861 aggtagctgc aatatttata gagccaattg caggagatgc aggaataata gtgcctccag
    13921 tagagtgggt acaaggttta agtaaaatat gtaaagaaaa tggaatatta cttgtaagtg
    13981 atgaaataca acaaggtatg ggaagaacag gtaagtggtt tggtatagaa aattttggtg
    14041 ttgaagcaga ccttatagtt cttggaaaat ctgttggagg tggattacct ctaggagcag
    14101 ttgttggaag aacagaaata atgcaaagtc ttgatgcacc agcacattta tttactttag
    14161 ctggaaacac aacagtatgt gtggctgctt taaaatctat agagataatt gaaaaagaaa
    14221 acttacttca aaagagtata gaaatgggag attatattaa agcaggattt gaaaaactaa
    14281 aagaaaaata cgatataatt ggagaaataa gaggcatagg attatctata ggagttgata
    14341 tagttaaagg aaaaggttct aatgaaaaac atccagatgc tacagctaag atatgttata
    14401 gatgtataca aactggatta ataatgatat tcttaggaca atctacttta agagtgcaac
    14461 cacctctagt aataactaag gagcaagtag ataaagcaat gaatatcata gattctgcaa
    14521 tagatgatta tttaaatggt agaattggtg atgaagtata tgaagtaact caaggttggt
    14581 aaaataaata ttaaatgaaa ataggagtta tctcaatttt agaaaattat ttctgaaaag
    14641 agataactct tttaagttac ccacaaataa gaaaattgtt tgattcatta aagactatat
    14701 ttcggatgtc gtttttgtga gtatcagaga cagtattacg agaataatta cctttattcg
    14761 tactatctgt taatttagtt ataattaaga tagctaaaag aataagaatt actgtgtata
    14821 aagcaataac atatggtttt cttttatatt tgtatttgtt attgaaaaaa gaatggccat
    14881 aattattttt atttacttta gatgtatttg tattcttttt cttgttacct ttctttttat
    14941 catccttttt tctattttta gggtaaggaa tgactttgtg tgtattatca agtttgatat
    15001 ttttattttt ttgaatattg ttttctaggc tagccttttt ttctccaaat tgaatagttt
    15061 tattggtatt gttgttatct ttcaatgtta atctccctcc cttaaacttt ccctttagat
    15121 aatattacta ctaacctatg gaatatacaa taaataatat ataagtaata aaattttata
    15181 ggtataaatc tctttctcca cgctctaagg cagtcatatt gttagatact atgtttctta
    15241 tatcttctct ttctatctta cctatttctt ctgcgataag ttttttaccc ataattttaa
    15301 gttcttcatc tccataatcg attaaaaatt catttaatgt agtaagagca tttggtgtac
    15361 atacattatg gatttgtcga cttttagcta agctcatgaa tctatcgcca gttctacctt
    15421 tacgataaca agctgtacaa taactaggta tatatccatc agtaatcagt tctttaagca
    15481 cctcaacagg gcttctatgg tctccaactt cgaattgttc tgtattgtca ccatcttcat
    15541 atgctttata tcctccaaca cctgttagag aacctgcact aatttgtgat acaccatatt
    15601 ttagtaactc atttctcatt tcagcagttt ctctagtgga cattatgatt ccagtaaaag
    15661 gaacagctaa tctagttata gctactattt ttttgaacat atcgtcagaa actaagtgag
    15721 gaaaatcttc taagctcata ccttcagctt ttttcaatct agggaaagat atagtatgga
    15781 aacctacacc aaatttttcc tctaagtgtt cgttgtgcat cataagtcct agaacttcaa
    15841 atttagggtc agataaacca aataaaactc ctgcaccaac atcatcaaca ccagcttcca
    15901 tagctctatc aaaagctgtt aaatggtaat aatagtcatt ttttatagat tgaccatgca
    15961 tttttataaa tgttggtttg tgataagttt cttggaataa tatataagtt cctattcctt
    16021 tttcttttag taatttatac tcatctacac ttgtagctgc tatgttaacg tttacccttc
    16081 ttatatttcc gttttcatta tatgttgaat aaattgcatc taagcaatct aagatgtaat
    16141 ttatatcaca atttttaggg tcttcaccag cttctagagc aagtctttta tgacccattt
    16201 tttctaatat tttaacctct tcccttatct cttccatggt aagttttttt cttttaaatt
    16261 tgttgcattt actaaaaccg caataaacac attcatttac acagtagttt gatacataaa
    16321 gaggggcaaa taaaaccact ctattaccat atatttcatt ttttatttgc ccagctatac
    16381 taaataatct atctagttgt tttttatctt ctacttcaag aagtgtagct atatctttat
    16441 aactaagttt ttcccttcta tcagccttat caagtacctt ttcaatatca tcagaagttg
    16501 aattttttgc atcttctaat aaagaattaa taagttcatg gtttatgaac atttacaaac
    16561 gcctccattc aatattatca ccgcgagaat agtcaacttc aagtcctaat gacttgatgt
    16621 tttcttctaa actttggtga tattcacaag cttcttgacc agtaaaggct ttgttatcgt
    16681 aaagagaata ttgttttcta aattcttgag gagaaaggtt tggcataatt acattgcaac
    16741 cagctaaaag acctgcattt ctaccactag ggtttataga tgccaaggct gttgtagcgg
    16801 gtaataaaac ttttggaagt agaagtcttg taattgaaag cataagtaat gtcttctcta
    16861 aatctccatg tttataatcc ttaaaaattg tatcatggtg tggaatgaaa ggtcctattc
    16921 caaccatatg aggatttaac tcttttaggt ataataaatc acgaacaagg tcttcgttgt
    16981 tctgaaatgg tgattcaacc ataaatccag cacctacctg ataaccaatt tctttaaggt
    17041 tttttaggca ttcttttcta gttctaagct caatgtttgg cggatgtaat tttttataat
    17101 gactgtctgt agcagtttca tgtcttaaaa gatatctatc tgcaccacat aaaaagtatt
    17161 ttttatacga atcataactc ttttctccta gtgatagagt tatagcacaa tcctcatatt
    17221 tattttttat acttgaaaca atttcacata ttttatcatc agtaaaatat gcatcttcac
    17281 caccttgcaa aacgaatgtt ctgtatccta ttttataacc tatatcacaa cattcaagta
    17341 tttcatcaag tgaaagcctg tatcttatga tatttttatt agaagattgt attccacaat
    17401 agtagcaatt atttttacaa tagtttgtaa gctctataag tcctctcaag tagactctat
    17461 ttccataatg tttatttctc atgtcgctag cttgtttata aagatagttt cttaaatttt
    17521 gttcgaagtt atattcctca ttgtcgatat tttctattaa atatagtagt tcatcaaaac
    17581 ttaatgaatt aatgctgtaa agtttatcta taaagtattt aatcttattt ttagtcatat
    17641 tcaaatatgt aattattaag tatagttaaa tttttaataa ttgaaaagtt caagtgatct
    17701 ttccaaaata ccttttacat atgctattaa gacaccatag tttacaatag gtacattgaa
    17761 agattttgcc ttttctattc tagataacat tccagctcta ttcatcatac aagctccaca
    17821 gtgaactaca agggcatatt tatttatatc ttcagtgaag gatactccag aactaaattc
    17881 aaaagtaatg tttttgccag ttttctttct aatcatatta ggaattttta ctgttccaat
    17941 atcatcagtt tgtctatgat gggtacatcc ttcggccatc aagattttat caccatcttt
    18001 taaattttct aaagcataag ctccattaat caattcttta aggtctccct tttgtctagc
    18061 aaacaatata gaaaaagatg taagaggaat atcttttggt gtatctttat ctacttgtgg
    18121 aaatacttga gagtcagtaa taacaagttt tggttttttg cctaaattag atagagtttc
    18181 ttttaaacta tcttcttttg taactataga aattgcacca ttatccaaaa tatctcttat
    18241 aacttgctgt tgaggaagta taagtctacc ttttggagct gctttatcta ttggaacaac
    18301 taaaacaact aaatcatttg gttcaattaa atctgatacc aatttgaact cagtgctatc
    18361 cttaggcaaa acttttatta tttcattttt taaattttca attccaattt tatctgttga
    18421 tgagacagaa acaactggac atttaacttt atttttagtt aagtttaaaa tttctgattg
    18481 attcttaata gtatcaattt tgttaagaat tagaatatga gggatattct tatcattaaa
    18541 tttttcaatt agtgacaaat cttcttgtga tataccaatt tggcaatcca ctactagtaa
    18601 agctatatct gtcttttcta aaacatctag tgatttacct attctaagtt caccaagttc
    18661 accaacatca tcaagaccag cagtatctat aagaacacaa ggtcctatag gaaggatttc
    18721 cattggtcta aatactgggt ctgtagtagt tccagcaata tctgagacta ttgcagcact
    18781 ttgatttgtt atagcattta ttatgctaga tttacctgca tttcttttac caaagagacc
    18841 tatatgtact cttaccgatt gtggagtaga atttagactc atttgtactc accaccttaa
    18901 acttcttttt ttgatatact agtttttaca gatacatgag gtatgttgcc caatttacca
    18961 gtcaaactat taatagtatc catttcgcca acaactgcta tacatacgat tgagacacct
    19021 tcttcttcgc aaggaatgcc cattcttcct ttaataatac ctttaaaacc tgatacaacc
    19081 tcattgaatt taaattgaca ttcttttggc tcttccaaaa tagcacttat aactgcaacc
    19141 tttttcataa atatcctcct aactcagaaa atatgtctta aacaaatcca aaatcaaaaa
    19201 acttttcttt gtaaagaaaa gtttctacaa aagaaaagtt attaattaca caagtataat
    19261 gtgctatatt aaactatttc cttacagatt agataactct tttctggtag ggttagcttg
    19321 taaaaattta atttaacaac aagtaactga agaaaatttt tatacaattt atataaatta
    19381 taataaaaat taactaaaga aaattgaagt tacttatata atagtagtaa attgaaatta
    19441 agtctataga aaaaccaatt tttgtataaa aataaaaatt aaagttaatt atttgttaag
    19501 aattgacttt ggtaaaatat ataattaatt attctttaag catataattt ataagtaatt
    19561 ttagtgtatt ttcaatagct tctatatgtg ttctttcata atggtgacta ttgtttgttc
    19621 caggaccaac acatgctatt tgaacatctt ctccccaacg aatagcttct gaagcatctg
    19681 aaccatagaa agtaaataca tcgacagcgt agtctaaatt attgtcttct gcaacatcga
    19741 caagcttgtt tcttaaatta aaatcatata atgataaatt atcttttgca actatagtta
    19801 caccatgttc actagatgtt tgacttggtc cagtaggtgc tatatctatt gctacaaatt
    19861 cttttgtttt ttcaggtaaa catttagaaa caccatgtcc aatttcttca taattactta
    19921 tataaaagtt agtagtatgc ttaggtgtta aattgttttc tttaaaatat ctacatattt
    19981 caagaaccat tgctacagct gatttattat ctatatatct agattttata aaaccagatt
    20041 ctgtagcctc aaatctatgg tctaggcata caaaatcccc aacacttatt cctaaatcta
    20101 atacatcttg ctttgtaaat actttttcat caagtctaat aatcattgtt tcttcatttc
    20161 tttcagtggc agcttttgtt tgaccatata tatgagtaga agcatactta aatacaacac
    20221 ttcctctgat ttttttacct tttctagtta taacagtaca gttttctccc tctatagctg
    20281 cccaacatcc accaccaact ttatggtatt taagagtacc atcagatgat atttctttta
    20341 ctatagctcc aagtgtatcc atatgtgcag atattgttat ttgatttgaa tcatcttcac
    20401 caggaagagt agctataagt gcaccttttt ttgtaagaat agtgtcaaga cctaaatttt
    20461 caaaatcttt tttgatttct aaaactgcat tttcagtata tccagctggg cttggaatgt
    20521 ccaaatattt tttcattaaa tttatagtat tagttaaatt taaattcata ttgtttcctc
    20581 ctaaataaat atatttatac aaattataac ataaatacaa atgttctgaa aactaaaatt
    20641 aaaagaaggg aatctaaaca tatttaaaaa aaaagtatat aaaa
//
LOCUS       DAEPUT010000073        20214 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.075, whole genome shotgun sequence.
ACCESSION   DAEPUT010000073 DAEPUT010000000
VERSION     DAEPUT010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20214
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.075"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            144..332
                     /locus_tag="KRL22_002861"
     CDS             144..332
                     /locus_tag="KRL22_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH1273312.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(386..1255)
                     /locus_tag="KRL22_002862"
     CDS             complement(386..1255)
                     /locus_tag="KRL22_002862"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HBH1273313.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(1452..2696)
                     /locus_tag="KRL22_002863"
     CDS             complement(1452..2696)
                     /locus_tag="KRL22_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273314.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINSKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            2987..3298
                     /locus_tag="KRL22_002864"
     CDS             2987..3298
                     /locus_tag="KRL22_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH1273315.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      3391..3483
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            3583..4377
                     /gene="thiD"
                     /locus_tag="KRL22_002865"
     CDS             3583..4377
                     /gene="thiD"
                     /locus_tag="KRL22_002865"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBH1273316.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            4401..5189
                     /gene="thiM"
                     /locus_tag="KRL22_002866"
     CDS             4401..5189
                     /gene="thiM"
                     /locus_tag="KRL22_002866"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBH1273317.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            5212..5844
                     /gene="thiE"
                     /locus_tag="KRL22_002867"
     CDS             5212..5844
                     /gene="thiE"
                     /locus_tag="KRL22_002867"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH1273318.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGKNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDIPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            5983..6285
                     /locus_tag="KRL22_002868"
     CDS             5983..6285
                     /locus_tag="KRL22_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1273319.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(6351..7100)
                     /locus_tag="KRL22_002869"
     CDS             complement(6351..7100)
                     /locus_tag="KRL22_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273320.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(7094..8056)
                     /locus_tag="KRL22_002870"
     CDS             complement(7094..8056)
                     /locus_tag="KRL22_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273321.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(8060..8518)
                     /locus_tag="KRL22_002871"
     CDS             complement(8060..8518)
                     /locus_tag="KRL22_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH1273322.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            8874..9230
                     /locus_tag="KRL22_002872"
     CDS             8874..9230
                     /locus_tag="KRL22_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1273323.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            9302..10018
                     /locus_tag="KRL22_002873"
     CDS             9302..10018
                     /locus_tag="KRL22_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273324.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            10011..10835
                     /locus_tag="KRL22_002874"
     CDS             10011..10835
                     /locus_tag="KRL22_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273325.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIVLITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            10847..12046
                     /locus_tag="KRL22_002875"
     CDS             10847..12046
                     /locus_tag="KRL22_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273326.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKAKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILSSKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDNKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            12055..12867
                     /locus_tag="KRL22_002876"
     CDS             12055..12867
                     /locus_tag="KRL22_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273327.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            12878..14146
                     /locus_tag="KRL22_002877"
     CDS             12878..14146
                     /locus_tag="KRL22_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273328.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            14512..15693
                     /locus_tag="KRL22_002878"
     CDS             14512..15693
                     /locus_tag="KRL22_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1273329.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(15835..16752)
                     /locus_tag="KRL22_002879"
     CDS             complement(15835..16752)
                     /locus_tag="KRL22_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273330.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            17005..17799
                     /locus_tag="KRL22_002880"
     CDS             17005..17799
                     /locus_tag="KRL22_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273331.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            17800..19860
                     /locus_tag="KRL22_002881"
     CDS             17800..19860
                     /locus_tag="KRL22_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1273332.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLSLLFAYYIKADFKEVFSLKVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         7801 a         2240 c         3100 g         7073 t
ORIGIN      
        1 aaataaactt tataaaaatt attttaaaag gtattttttt caaatttgag gacataataa
       61 aaaagaactg aatgttacag ttttggttca tcaatctttg ataaacaaga ttttaaattt
      121 gtagcgtcta ggaggatttt attatgaaag caaatgttaa tcaagatact tgtataggtt
      181 gtggattatg tccatcaata tgtccagaag tatttgatat gaaggatgat gggaaatcac
      241 atgttatagt tgatgaagta ccaagtgatg ctgaagaatc agcagcagaa gctagagaaa
      301 gctgtccagt tgatgcaata gatgtgcatt aataaaataa atgcctataa aaattgaatt
      361 ttcaattttt ataggcattt gtcttttatt cagttagtat ttcaacacct gtttctgtaa
      421 ctaaaaccat acattcccat tgagcagata atttaccatc ttttgtataa atagtccaat
      481 tattttcttc atcaacaaaa atttcgtgag ttccttcatt taccataggt tctattgtga
      541 atatcatccc aggaaccaat agcatctcag tccctttttt ggatacataa cttacaaaag
      601 ggtcttcatg aaagcttaat ccaactccat gaccacctat ttctctaaca acagagtatc
      661 catttttctt tgcataagag ttgatagcat cacctatatc tcctaaaaat ccccatggtt
      721 tggcaacttc aagacctttt tggacacatt cctttgtaac ttgaactaat ttttttgcat
      781 tttcattaac attacctatc ataaacattc ttgaagcatc tgaatagtat ccattaaaaa
      841 tagtagaaac atctacattt ataatatctc catcttttaa gataatgtcc ttacttggaa
      901 taccatgaca aacttcatta tttactgatg tacatacact tttaggaaat ccattatagt
      961 ctagtggagc agggatagct ccattttgta gtgtaaagtc atgaaccaac ttatttatat
     1021 cttctgtaga cattccaatt tcgattttat ctgaaatata atccaaaatt tttgtgttta
     1081 ttacagcact tttttttatt tcctcaattt gactttcatt ttttataata tcatgagttg
     1141 gtacaatatg acctaactta gcaaatgaat ctattttatt atccatatcc atatgacatt
     1201 ttttatattt tttagtactt ccacaccaac agctatcatt tctatttaac ttcataactt
     1261 ttcatccttc ttttattatt tatttaaatt atgggttaca taaactattt taaaacataa
     1321 ccattataaa tattataaca taaatactaa gaaatccttt atagatagtg atttattcaa
     1381 agtataaatt attatatggt tattgttgat gaaaagagga tagttaaatg tattattgga
     1441 tattagcgca cttaatagtt tagttcaagt ttttcaagaa aatcatatgt tagaggacaa
     1501 ttttccttta aagtattttt tgaatcttca tcaagataat aatgtacaaa tgattctgca
     1561 aaaaattctt ctataaactt gcttatatat gcatgtgcaa cttgcttagg gtcataaagc
     1621 ttatatcttt cctgagcaaa tacttccata aattcttcag aatttgattt tttatttaaa
     1681 acatttttat ctatagcatg tgcagtttca tgtaattcta aattttttga tgaatgtaca
     1741 tttgcatagc taggattact ataacctatt ttagccacta tagaattatt tctatatata
     1801 ccaggtacat ctttccaagt cttgcctgat cttacccaac atggaggtaa ttgatatttt
     1861 aaatcactaa attctggttc atcagttaga tttgaattta ttaattttat ttttatatcc
     1921 ttttctttaa gtgtctgtaa atatttacta tttatttttg caagtctgtt tttcatattt
     1981 tcaacttcat ctttatcata attcaagtca tcaggaagta taagcatttg ttcaattata
     2041 tctatactac tgtcttttat attttcagat tcttcatcaa atttatattg aagagtatta
     2101 ttttcataga tagttatatt tgtattattt tctatagaat aagagtgaat atcctctaaa
     2161 tctaaaatat tcatttgttg taaaatatgt tttgtttcgc cactccatac tactaaagaa
     2221 agtgaattaa aattaattag tggattttct tttgctttta tatcattgct tatatctaca
     2281 tcaaatacat attcaattga gtcttctatg ttaagactat ctgtattctt tttaatatat
     2341 aaatacgctt gttttaagtc tatataaatc tcatctaaag attcgtcata aaattctgat
     2401 aaattattag taaagagttc ttcacttaaa agttcatttt tatcagttat actttcaatt
     2461 aaaatattaa tttcttttat catatcgtaa atacttattt ttctatttgc tttttcacta
     2521 gatacattgc atggcgcaag agcaatgcaa taaaaatctt tttctttttt ataaaaggct
     2581 ttaagtgatt ttgataaaag tgtaaagtct acacctatct gtaagttgac cttaagtgag
     2641 tcattttgta ataattcagt attatttctt ttagctgtat ttaaattgtt ttccataatc
     2701 attgccccct ttttattagg gtatcataat ttttttatat gtgtcaattt gtttttttga
     2761 aaattataat ttttttgaaa attttatttt ttataatttg tgaatttttt attatagaaa
     2821 taaatatgtt attattatgt caaaatttag cattagattc atgtagagta tgttttatac
     2881 atatattata attaattctt tgaagattgc atattcaaaa tacacaccat tttttttaat
     2941 tctataatat aatatttata tatttaatgt taggatgtga tttaaggtgt attttacata
     3001 tattataaga tgtaaagatg attctctata cactggatat accagtaata tagttagaag
     3061 aatgaatgaa cataaattag gaattaattc aaaatacaca agagcaaagg gatttgaaaa
     3121 actagaagtt tattttgtga ccaacacaaa aagcaatgct atgaagttag aatactatat
     3181 aaaaaaatta actagaaata aaaaattgtc tataataaaa aacccaagta tacttataaa
     3241 tttaattgat aataaagaag attatattat tggtaaggaa atagaacaat taacataaat
     3301 atttatagta acattataat gggtgcatat ggtgtaaaaa cttgacaata aatactattg
     3361 taatataatg aagttataaa tatagtaaat taaaatagct aggggagcca agagctgaga
     3421 ggtataccga cccttacacc tgatctggat aataccagcg taggaaagct tagtaaaaat
     3481 tcaagtatgt attatttgtg atatatgcta tttctaagct atacctattg taggtatagc
     3541 ttttttaatt aagttattta aattaaactt taggaggcaa caatgagtaa ttataaaata
     3601 ccaacactta caatagccgg ctctgattca tctggaggag ctgggattca ggctgatttg
     3661 aaaacgttta gtgcaattgg tacttatggt atgagtgtaa taacagctat aacagcacag
     3721 aatactaaag gagtttttgc tgtagaggat ttaaataaga aaataataaa aaaacaaata
     3781 gaggcagtct ttgaagatat acctccaaga gctgtaaaaa taggaatggt ttcaagtcct
     3841 gagattatac ttgaaatagt tgagaatcta aagaaataca atccaaaata tttggttgtg
     3901 gacccagtaa tgatatctaa aagtggatat tatctattaa agccagaggc aaaagaaaac
     3961 ttaattaagt atttgatacc acttgcatac ataattacac caaatatacc agaggcagaa
     4021 gaaataacag gaataaaaat acataatgta gatgatatga agagagtagg agaagaaata
     4081 ctacaacttg gacctaaatt tgtacttatg aaaggaggtc atttagatgg agaagcagtg
     4141 gatattttag ttggtaaaaa tatatttaaa gtttataaaa gtgaaagaat tgataaaaaa
     4201 aatacacatg gaacagggtg cacattatct tctgcaataa catcttatct agcattagga
     4261 tatgaaataa cagaagcagt aaatctaagt aaaatctata taacagaagc aataaaaaga
     4321 agttttgata taggtcatgg agtaggacca gtacatcatt tttataaatt tgagtaataa
     4381 aaaaatattg gaggtagaat atgtataatt taattaaaga tgtaaaaaaa ttaaatccat
     4441 tggtaattca ttatactaat aatgtaacta taaatgattg tgctaatgta actttagctg
     4501 taggagcaag tcctcttatg agtttttcat atgaggaagt agaagaaatg gtaagtgtag
     4561 caaactctgt agtaataaat ataggaacta tgaactcaaa tatgttggat ttattcctat
     4621 tagctggaaa agcagcaaat aagtacaata aacctgttgt tttggaccca gttggagtat
     4681 ttgcaagcaa agcgagagca gaacttacaa gtagactttt aaatgaagtc aaatttagtg
     4741 ttgttaaagg gaatgtatca gaaataaagt ttataggtgg ctttaatgta aggggtaaag
     4801 gtgtagattc atttgatgaa gaagaagatt ctactgagat aataagaaag attgctgaaa
     4861 agcttgaatg tgtagttgta gcaactggaa aaatagatat aataactaat ggtaaaggta
     4921 catataaaat aaacaatgga actgataaat taaaaggaat tacaggaact ggatgtatga
     4981 ctgctagctt gattgcaagt tttatggctg ttactgagaa tatattagaa gcagcaacaa
     5041 tgggtgttct tacaatgtct ttaagtgggg aattagctaa tttaaataat ccaccaatag
     5101 gtacatttaa agaaaatctt atgaatgcta tttatcaaat ggatatagat actttaagta
     5161 aaaattctaa tattgaattt ttaaattaat aaagagtaag ggagacttaa aatgattgat
     5221 aaagaatctt taaaaaaatg tttaaagttg tatttagtaa ctgactctga aatgcttaaa
     5281 ggtagagact tttataaatg tcttgaagat gcaatatctt ctggaataac aactgtacaa
     5341 cttagagaaa aaaatgcttc tggaagagag tttttaagaa aagctatgaa acttagagaa
     5401 ataactaaaa gatatggtgt taagtttata ataaatgata gagtggatat agcacttatt
     5461 tgtgatgcag atggagtaca tgtaggacag agtgacattg atgttagaga ggttagaaag
     5521 cttataggaa aaaataaaat tctaggagta tcagcaagaa ctttagaaga agctatttgt
     5581 gcaaaaaatg atggcgcaga ctatttaggt gtagggtcta tattcacaac atctactaaa
     5641 ttagatgcaa aatcagcttc gtttgaaact gttaaagaaa ttaaagaaaa agtagacatt
     5701 ccatttgtac taattggagg tataaattta gacaatatag ataaacttaa atgtttagaa
     5761 agtgacgggt atgctataat atcagctata ttaaaagctg aagatatctc taaagaagtg
     5821 gaaaagtgga cattaaaaat ataaaattgg ctctggtagt gaaaaaaatg gaaaaatttg
     5881 atataatcta agagtaaaat ttaagcaatt ataaatgata aacttttcta catatacttt
     5941 ttaatcaaga tatatgtaga tttggttaaa aaggagctat aaatgattag gatattgtta
     6001 gtgtgtgttg gaggcatgtc ttctacccta ttggtaaata aaatggagaa ggatgcaaaa
     6061 aaaagaaata tagactgtaa aatatgggca gttggagaag gagatataaa atcggagctt
     6121 gataactttg atattttact tcttggacca caacttagat ttatgcttga tgacgtaaag
     6181 tctatagttg gagatagagc tccagtatct ataatagata tggtaaacta tggcacttgt
     6241 aatggtcatg ctgtgttaaa ttcggtttta gaaatattaa aataaataat aaaagtggat
     6301 tctatataat agagtccatt tttattattt gttattaata ggcttaaaac ttagcttacc
     6361 atttcttttt ttaatctcca catagcaagt gaaaaacttg aacagcacaa tattaaaaat
     6421 agtaggataa caggcagtat atctccaata agaatagtct caccaaatat taagctacgt
     6481 aaagcgttaa taacatgggt aaatggattg agcatcactg ctacttttaa tcctccagat
     6541 aaactttcta tagggaaaag agctgaactt aaaaagaaaa taggaagtac aattgcagtc
     6601 ataattgttt cataaactat ttcatttggc aataataaac ttatagaata agctagactt
     6661 gataaaaaga aggctgtcat aaatatcagt actatcataa gtaggattcc accaatgcca
     6721 gattctatcc ttactgagaa gaatatactt actatacaca aaatagttac ttctatgaaa
     6781 gaaactaaga tagcttctaa taattgacca aggacgattg aatacctgct gataggtgca
     6841 attaagactc tatagaaact tccactgttc ttcattataa agtttataat accaccacta
     6901 ctacaagaag aaaacacaac cagtacaatg atacctggta gtataaaagc agtataatta
     6961 ttgatattta tattattcat agtttggttt gcaatagaac tataaagcac aagccaaaga
     7021 aaaggttgta atatagtaac tacaaatgag attggatttt taaaacgcca cttcatacta
     7081 cgccataaga tatttaacat tcccattcct cctttaagct ttttttagaa cttgtaagtg
     7141 ctaaaaatac atcttcgaga cttggctcta caatttctat tgcatcaaat tctatatcat
     7201 gttctaaaag ccatttattt attaaagtaa aagcagttct actatcgttt acacttataa
     7261 aaattgaatt ttctcgtacg ctcataaact ttactaaacc agtactttta attgaatctt
     7321 tatatttttt tatatcttca gtattatgaa aagttatacg tagtatattt tgtctaatgt
     7381 aactacgtaa acttgatggt gttccttgtg ctaaatcctt tccattcttc ataatacaaa
     7441 tattatcact caattgttca gcttcttcaa gataatgagt agttagaaat atagttgtgc
     7501 catactcatc tctaattttt aataacatat cccacataga ttttcttgaa tcgacatcca
     7561 taccaacagt tggttcatct aaaaatagga ttttaggaga tgataccata ttcatagcta
     7621 tgtccaatct acgttttaca ccccctgaat atgatgaagt aggatatttt aagtaactag
     7681 ataagtcaaa cttatcaatt aaagagtcta ttctttgttt tgcaatctgt ggttctactt
     7741 tatacatttt actttgaaat accatatttt ccataaggga taaatgttca tcaatagaga
     7801 tttgctgtgc tacacaagca atttgagtac gtatccaaga aggattatct actaaatctt
     7861 ttccaaacat tgttacattt ccagatgtag gtttgtaaaa ggtagtcaaa atatttataa
     7921 gagaagattt accagcacca ttaggaccaa gtaaagaaaa aatttctcca gcatttacat
     7981 taaagcttag accatttaaa gctttcacac catttttata ttcttttact aaattgtcta
     8041 tttcaatcgc taacatatat tattcctcct ctttaagtgg aaatattatc tctgtaatat
     8101 agttatctgg atttcctttt atcaacatac ctggtccttt aataaatact tctctccaag
     8161 gagtttgtat ttttatatta ttttcatgaa tatatttaaa tatcatttca tacgtttttg
     8221 gcaaattact ataagagcct gtgtgagtaa aaaataaagc ttttgtttta ggaaattctt
     8281 ttgtagttat acccatacga tttggagttt cagcagttgg aacacataat tccatttctg
     8341 caacaccagt tttttggtca acatcatagt agcaaaagaa tggtgcaccg ttagactttc
     8401 cttttatagc tttaaataca tttggaaaat actttgttgc ctcagtcata ggtccattat
     8461 aacgcatggt agccactgtg actgattcga tatttttgat ttcaattttg caattcattt
     8521 gtttacctcc taatgtgtgt tcatattctt actagatttt taagcattaa tacatataag
     8581 attttgatta gttgaaaaca tataatctta tatcgtttgc ttgttttcaa gtctaacata
     8641 acataaaata tatatcctct catttgatgc tccattttgt aaagttatta tttaagcttt
     8701 actttagatt ttttagcaaa ttaaaataaa gcaatttata aaataagtat ttacaaatta
     8761 agtgtattaa tcgtataata cacttaatag gatactagat aaagtctgaa ataaaggcgt
     8821 atttttttaa agtaagtgta ctatcgtatt aatacactag aataggagga atcatgaatt
     8881 ttgaattaga taatacaact cccatttatt tgcaaatagt aaagtatata aagagacaaa
     8941 tagtaacagg agagttgaaa ccaggagaga caataccatc aagaagagaa atggcactta
     9001 atctaaaagt aaacttaaat acagttcaaa gagcatataa ggagatgggt gatatgaata
     9061 taataaatac ttttaaaaat tatcaaagca gtgtaacagt tgatgaaaat atattaaaaa
     9121 atttaaaatt agagcttata aatgaatcac tatctgtttt tatagaagat atgaaagcaa
     9181 taaatgttag caaagaagaa gttttaaaaa taatagaaga taagtattag ttttttaaca
     9241 aatagaaaac ttagtttaga aagtttattt ataagcatat tggatgtgga ggatagtaaa
     9301 tatgatagaa ataaagaatg tcagcaaaac atataaaagg atgcaagggc ttaaaataag
     9361 aaagatagaa gctttaaaaa atgtaagttt taatatagaa aagggaaaaa taactgcatt
     9421 acttggtata aatggtgttg gtaaatcaac tatgttaaaa gcaatagcag gacttataaa
     9481 cattgatagt ggagaaattc gtatagatgg agaaaaaata aatgaaaagg tatacaataa
     9541 attggctttt gttccagatg tacaatctca ctttagcaat acaacaataa aagaaacatt
     9601 tgaatttatg gaaatttttt attcaaagtg gaataaagaa aaatcaaaag aaatgatgga
     9661 catatttaaa ttggatgaag atgaaataat tgataacttg tcaaaaggaa acattgcaag
     9721 agtaaaatta atacttggat tttgccaaga cccagagtac atacttcttg atgaaccatt
     9781 tacaggaatt gatttgttta agagggaaga gtttatagga gtaatagcgc aatatatgga
     9841 ggaaaatcaa gccattatca taactactca tgagatagta gagatagaaa gtttagttga
     9901 tgaggttgta attcttgatg aagggcagat tataacttca tttaatgcag aagaattaag
     9961 agaaagagaa ggtaaatcta tattagataa gatgagggag gtatataaga atgaataaac
    10021 ttctatatct aataaatgta gatttgagaa gaagcaataa gttttatata gcttatatat
    10081 catttttttc attaattaca cttagtttaa atttattcga aattaataaa tttaaaaatt
    10141 ctaaatttat tatgaactta gcaatagaag attttggagg tatattttat ggactaggga
    10201 tacttagtaa tcttggtttt atccaaagta tattgttctt tgggatattg ggacttttta
    10261 tatactatat ttttatgtgg aaaagagagt tcttttcaaa taatcaaagt atttatacac
    10321 ttatgatgtt acctcaaaat aagtttaaga tttgtatatc taaatcaata gttttgataa
    10381 caatgatata tggttttttg ataagtcaga cagcaacatt atttatatgt aaatatatat
    10441 ttaatttcat ttttagaaat atgcctataa tcaatatgaa ctttgccaaa gatttatatt
    10501 atttaaactt gaagagtata ccaattgatt ttatctcttt tatggctatt tatgtatttt
    10561 tactacttat agctatttct attgtaaatt gctgtatatt atttatcttt tcctatataa
    10621 ataaatttta tgtaatttta atcactttgc tgattatagc aggcttatat ttttcaacaa
    10681 tatatataaa tataatcact ttatttagaa aatattataa tcttatagga tttcaattta
    10741 acaatttagt agcagggtta ttaagttttt taattataat gtttattcta aatggaatat
    10801 cttatttgct aattaaaaag aaagtatctc tttaaggagg ggtggtatga aattaaaatc
    10861 taaaatatct atacttatta tatttttgac tttagcaata tattttagta taggtttatt
    10921 aaataatgaa gataatttaa agataaaaac tataaaaggt gactctaatg aattagacca
    10981 tataaacata aattttggat atgctttgaa tggatatata aattcatatt atacaataaa
    11041 tggaagcaac aaagccaaaa agactgagtt aataaaacta caaaaggata gtaagaacac
    11101 aaataattta attgatgtat ctagtggttc agatttaatt gctcatgttg gatttgaaat
    11161 gaatgaggag tcaaaagata taaactttgt gatagatgag aaaaaagaag atttagaaaa
    11221 aggtgtattt ccatcagaag gtagtgataa agaaattgaa tatgaaaaat tagatatgaa
    11281 taattttaca aggacaagat ataaagtaga taaaagtaca gatgattatt atgcaaagat
    11341 actatcatca aaaagatata aaaaatactt atatgtatct gtactttatg ctacaagtga
    11401 ttcatcagaa aataacaaag aatattcaag tactatagat ataataaaaa ttaatccaga
    11461 aaataaaaaa atcaagacta taaaaagtat aaatttaagt aattattttt ccgaaaaata
    11521 ccaaaacata gagaacatag gtgtaagtta tgctagcaaa tatgaggata agatgtatat
    11581 tttagtaaat gtactaaata caaacatagg tgataatagt aattctaaat ttcatttact
    11641 tgagtataat cttgaagaaa ataaggaaag cataatggaa ttaaaaactg atagcaaaat
    11701 ggctttagca aaagcaaagt tagaagctaa taaattatat atggtaatgt cgaatgatta
    11761 tgataatagt tcaattacag agttaaattt acttacctat aatatattag ataaaagctt
    11821 agatgaagat aaatatgttt tagataatag agaaaaaaga ggaattagaa gtattgaaat
    11881 tgattcaaat aaaatcgttg catatacatc aaggctaaac tctatattat cttgggataa
    11941 taaatttatg ctatatataa taaataaaaa ttctaaggaa attgtatatg aaggagaatt
    12001 acaatttaac agttcaaata gtatgttaga atttgaaata aagtaggtga gttgatgaaa
    12061 gatttaataa gattattcga atttgaatta aaaagaaata taaagaatta tatatttata
    12121 ataatttgtt gttgttcttt tgtaatttta aacatagtaa aaaatttaaa tgactataat
    12181 tacataatag aaaatgcagt taaaagtgaa cagttaacaa aaatcggaaa tacgatagaa
    12241 acggtaaatg ttacaggttt ctcaagcttt agaaatataa tgggttctac agaatcgtgg
    12301 tttatgtttg gtataattgc atgtatttgc tatgcttttt ttatttggta tagagacttt
    12361 aatggtagaa gtaaatctat atatacactt ataatgctac ctaaaaatag aatcaatatt
    12421 tatatatcta aattattaaa tatattattt ctagtgtata gctatacagt agtacttaca
    12481 atatctttgt ttattgcaag taagttgttg cctagacata tgcttggtaa tgtcacaaac
    12541 tatggttttg tacaagaaac aatatatgag ttaaaaatgt tacttccata tagctttgaa
    12601 atactatttg tagagtatat atttttattg ataggatttg tatctgtagt atttacatca
    12661 attcttataa ataaatctat ttataaagta agcactttaa taagttttct atttttagtt
    12721 atagaaattt tagtgtttat aatttctata gaatttatta taccttacga atacagtgat
    12781 gtatttactg ttctatattc aagtataaac atatttgtat gtagtcttat atctaataaa
    12841 cttttgaagc aaaagattga cttttaggag ggatattatg aaagcaaaaa atataggaaa
    12901 atatacaata tgttttataa tagtatgttt tttaatgatt actatgacct taatattgag
    12961 ttattttaat aaggataaac tatctgtaaa aactttaaaa ggcaatgtaa aagatatagg
    13021 gagagtaagt gtagtatata cacctaatat aagcaaattt tcttatgagg aggtaattat
    13081 aagtaaaaat ggagtaagaa ataatacaaa cccaaaatca agaattagaa atgattattt
    13141 aaatattgac aaaaaataca gtgactttgt taatgataaa ggaaaagaat ttatatataa
    13201 agatgatttg aatataggag aagcgtatac ctctgttaag tctgatttag tacaaggaat
    13261 gaatgcttta aatgattgta taaaggtttc aaataaaaat ttaaaaagtg gggtagaaga
    13321 aaattttgat attaatttaa ataagtctga ttttaaagaa aatagttgga aaaccttatt
    13381 taacaaaata tataaaggta atttatatat ggtaattagt gaaactaata tttcaggttc
    13441 taaagtcaat aatatttgta tattaaagat agatataaaa aataagtctt ataaattatt
    13501 aaatagattt aatttaggat tacagaatgg agaacaacaa aatatcaatg aaattaaatt
    13561 ttctattgga agtaaattat acttagaaat agtaaataat aaaagtaaaa atggatatat
    13621 tgaaggacat gatagttact ctaactttat tatatatgat atagaagata acacttttaa
    13681 tataagtaat aaatttatgg ataatctaaa caaagaaaag aatgcaaatc caaaggagat
    13741 tggcttatta agtaaaacta agctagatta tatggtaaaa aataataaat tgaatcttat
    13801 agttacggat atgagtaatt ccataactaa tcttgtttat gatattaatt ctaatgagat
    13861 taaattagaa gattatgaga tacttgattt aaaagtagat tataatgaag catcatctgg
    13921 agttaggaaa gttaagctac tggatgataa gatatattct atttcaggta ttaagaacag
    13981 tatatcagga gaattaaaag gatttaaagg gattgttgat gtggtcggaa ctaagccagt
    14041 aaaatttcaa gtatttgata tgaaacttaa aaagaatatt tatgaagctg agctaataaa
    14101 tggagatata agtttacaag aaaagttatt ttttgttgca aattaagtgt tagaattaat
    14161 tttagaactt taaactttta tatgtatcac agataagtat aagtaaggga gtgtctcaaa
    14221 ataaactttt tagctcatga gacacttttt ttatatgaaa tcaaatatat tttcattgtt
    14281 tagatttatt ttgataatga aaaaaagatt atctttattt taagaaagac atttatttat
    14341 aattatatac aaaaatattt tttaatgttt ttgtgtataa ttataacaat ttaatttaca
    14401 ttaatgcact taaatttgaa atagaatgct tatagtggta aaattaatta ttagaatatt
    14461 agaaataata aataaataat acattgtact taaaaggggg agaagtttaa gatgaacaaa
    14521 aaatatatta aagcagggaa tttaattgat ggaaccggaa atagtattat gcaaaataag
    14581 ggtataatta ttgatggaga tactatagtt gaaattgaag atataagaga tgatttaaat
    14641 ggatatgatg tgtacgatta cttagataaa actgttatgc caggcattat gaattgtcat
    14701 gttcacttga caatggagcc agttggaaat ccaaagatat attatgataa tgtatcagat
    14761 gtagagcttg tagtaaatac gataaaacaa cttgatgctt atttggattc aggagtaaca
    14821 tatattagaa gcttaggttg tcccaaatat gtggatgtac aacttaaaaa tcttatagac
    14881 aaagggtcta tagatggtcc tggtatagtt acttcaggtc cagttatatg tatgacagga
    14941 gggcatggat attattttgg tattgaaagt gatggagtgg atgaatgtag aaaatcagcc
    15001 agaacagttt taaaaaatgg agtagattgt gtaaagataa tggcaactgg aggtgtaaca
    15061 actgatggag ttgagccagg gtcaccacaa ttaactttgg aggaaatgaa ggctgctgta
    15121 gatgaagcta taaaagcagg taaaataact gccacacatg cacaaggaag aactggtata
    15181 aaaaatgcag tgcttgcagg aattacttct atagaacatg gtgtttattt agatgatgaa
    15241 ataattgatt tgatgcttga aagaggaact tacttagttc caactgtggc tgcaccatat
    15301 tttattctaa atgcaggaaa agaaagtgga ataactgaag ctactcttag aaagtgtgag
    15361 attgttgcca ttccacacaa agagtcattc ctaaaagcat ataaaaaagg aattaaaatt
    15421 gcagttggtt ctgatgcagg aacttcttat aatgaacatg gaaaaacata ttatgaaatg
    15481 aaactaatgt cagattatgg tatggataat atggatataa tagttgctgc tacaaaaaca
    15541 gcatctgaac ttttaagaat tgataaaaat tatggaactc tagaaaaagg aaagaaagca
    15601 gatgttatag ttgtaaatgg aaatccagta gagaatatag acgtacttgc agatgtgtta
    15661 gcagtattta aacttggtaa aaaagttaga taaatagtat aaaaataaaa aagagtgtct
    15721 aaagaaattt ttaaataatt atagacactc ttttttatta gtaataatta aatcttttat
    15781 actttagaaa atagattcta ttttatattt agatataact ctttaaaatc attcttatgc
    15841 aatataatct atagaatcta cacatacaaa gtatattctt gaatcattag aatttccaag
    15901 tactataaca tcatttttct tacctagaac ttcaacacca gttagaacca aactaccagc
    15961 tactacagta acttgattat ttatatttga catataaaga ttatctagga tacctttatt
    16021 acaacagcaa tcatcacaat cgcagttgca attacattct ttgtaatgtt ttttatcaag
    16081 atagtaacct aaagatgcta tgaaatcttc ataatctgca ggtgtaatat caaatgcaac
    16141 agctttaaga ttacacaatg atgctaaatc tacgtttgct aatggagtag atgcagcaag
    16201 tataaaatca attatagcag caagtattgc atctaatata gccccaaggt ctatcgtagg
    16261 aggaataact gcatcaataa gtgcaattaa ttcagctact cctggtatag ttcctatagt
    16321 attaattaat ccctcaagag ttaaagggac tggaatagga taagatactc taccagctat
    16381 atctattaaa tcacagttac aagcagaaaa tctttcaaaa gtaccatcaa gtccagataa
    16441 attatctttt ggaggagctg aaagatctat acctaccaaa ttagcaccta ctataaagaa
    16501 atctgagata aaagcaaatt gattaaagtt tacaaaaggt cttagagcat catatcttag
    16561 aagttctaag gcctctctca tacttttttt acaacaacat tgttttattt taggttcttt
    16621 atatttattt ggataattat agtatctatc agctacttga taattttcat agtatctttc
    16681 atttgtattt ggataatctt cctcatattc ttgtgtaaat ctaaagtcct ctctacattt
    16741 attattttcc actaaataca ctccttttat attttaattt aaatgtatag ataattaagc
    16801 ttatctatat agtaatatta tatttataat gtaaaaaaat gttacaaaag atattataaa
    16861 cgaataaaaa ataataattt gtcagataaa cttgtaaatt tttatgaata atccattcta
    16921 aaacaaaaaa ctgtgtataa aaaaggttta tatgttatat ttatataaat ataacatatg
    16981 aacgagaaag gagtggtttg ataaatgatt gaggtagata aattgtgtaa gtcttttaca
    17041 agggttgtaa aagatgataa aaataaaagt tcaataagaa agctaaagaa agtaaaaact
    17101 aaaaaagaag aattttttgc tgtaaataat gtttcattta aagttatgga aggtgaaatt
    17161 gttggaatac taggtccaaa tggtgcagga aagactacat tacttagaat gttaggtggc
    17221 atattaacac caacatcagg aagtataaat atttctggat atgattattc aatagataga
    17281 aattcagcaa aaaaagaaat aggttatctc tctggaaata caaaactata tggaaggctt
    17341 tctccgagag aacttctaac aacttttgca agtctatatg agatgtcaaa agaagatata
    17401 gaagaatcaa ttgaaaatat tgtaaaaata atggatatga gtgaatttat agataataga
    17461 attgaaaatc tatcaactgg tcagactcaa agaacatcta tagctcgttg tttaatacat
    17521 tctccaaaag tatatatttt tgatgagcca acactaggtc tggatgtttt aagtagtgca
    17581 tctattatag attttatgaa gaatgaaaaa ctaaggggaa aaactgttct ttactcaact
    17641 cattacatgg aagaagcaga aactttatgt gacaagattt ttatgattca caatgggaaa
    17701 ataattgcat caggaacacc acagagttta aaagaggaat ctggagtaaa taatttgaga
    17761 gatgtattca taaaacttgc cagaaaggag gacatttaaa tgagaagtaa gattgtaaaa
    17821 tacatattta aaaaagaaat gttagacata ttgagagata aaaagacttt atttatgatg
    17881 attgttgtgc cacttctttt atatccttta cttatgttat taatgattca agtaatgaat
    17941 atgtctgcaa gtagtatgaa tagtaaggac attaatatag cttttaataa taaacctaat
    18001 aaggttttag tatccatgat tgaagatgat aatttagaaa aagatactaa aaatacttca
    18061 aatgataaag gcaaaataag agtgttagat gtagataact ataaaaagtc attagaagaa
    18121 aataaaattg atgcttatat aaagatggaa gaaaaaaaat catctataaa ttatcaaata
    18181 tatataaatt cttctcaaga aaattcttct aatgcactaa aaagaattga aactgttttg
    18241 gataaatata aaagatttac catagaaaaa actttatctg aaaaaggatt agatgtacaa
    18301 gctactttag aaccaataac atatagcact gtagatgttg caaagacgga agaagtggca
    18361 ggatactttt taggtcagat acttccattt atattaataa taggagtttt actaggttca
    18421 atatatccag caatagatgt tatggctgga gaaaaggaaa gaggtacatt agaaacatta
    18481 tttacactcc caatatcaaa cttagaactg gttatgggaa aatatatggc agtttctctt
    18541 agtgcaatag taacagcaat tttaaacatt ttatctatgg gactgactat ggcatttatt
    18601 ttagttagtg gaggtattag tagccaattt ggctttggaa actttaatta tggagactta
    18661 gtcttaccaa ttataactac tttaatttgc atatgtcttt tttcaatggt agtttcagca
    18721 ataagtatgt gtgtatgttc attagcaaaa agttttaaag atgctcaaaa ctacataaca
    18781 cctcttatgt taattattat gataccatca tatgtttcta tgataccaaa tatagtatta
    18841 gatagagtaa cagctgtaat acctgtagta aatatatctt tacttataaa aagtgtatta
    18901 tcttttaaaa gcgatttaaa tttaatagcc ttagttttag catcaaatgt agcctttgtt
    18961 atattggcaa tcatactact gtctaagatg ttcaattctg aggaaatact ttttggtaat
    19021 agtaagagtt tctctttctt agagaaaaga agtaatataa aaaaagggtc tataccaact
    19081 gtaagtgatg gtgttatttt atatgcagta ggattagttc tattgattta tgttggttct
    19141 ttagttcaaa ttaaatttgg tatggcaggt attataatga cacaattcat gataatttct
    19201 ttatcgttat tatttgcata ctatattaaa gctgatttta aagaggtatt tagcttgaaa
    19261 gttcccaaat taaagcatgt gtttgggagc attgttcttt ggattggtgg atacatactt
    19321 attatgatta taacacagct aattttattc ttatttcctc aaaatatgga agttgctgaa
    19381 agtttaaata aggctctttt tatcaaagat agtgttttac tgaatttact agcaatagct
    19441 ttattaccag ctatatgtga agaaatgttt tttaggggat ttatattttc ttcatttagt
    19501 aaatcaaaag ataaaaataa gtctatcaag ctagctataa tatgcagtgg ggtactattt
    19561 ggcattatgc atatggattt tattagaata attccaacat caatattagg tattatattt
    19621 gcatatagtg tgtataaatc tggttcaata tttgtatcaa tgttattgca ttttttaaat
    19681 aatagtgtag cagttgtgtt aaatcattat acaactggaa atataaccaa cttatataaa
    19741 tttgttgaag ttgatttttc gaacttaaat gtacttaaat ttgccttaat tcttctaata
    19801 agtcttatat taattatgtt aggattaaga gttttagata gaaagtcttt aagaaattaa
    19861 gtataaagtt attatataga ttaaaatatt aataagcact aaagtatatg gatatatctt
    19921 gtatataaaa atactttagt gctattttat atattttaat tatatgaatt atttatcgtt
    19981 tcatttatgt aatgaaaatg ttatataaat gaaacaataa ataattttta ttttagaaat
    20041 ttatatttaa ataatcaagt tgaaagtgag atactaaaaa aattaattta ggaattattt
    20101 gatttattca tttataaaaa ttaattactg atttgtcgaa accattgtaa taagaaaaaa
    20161 atgaaaaaat aaagtgtgaa tatgttgcaa atactgtatt ttaataaaaa gtag
//
LOCUS       DAEPUT010000074        19883 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.076, whole genome shotgun sequence.
ACCESSION   DAEPUT010000074 DAEPUT010000000
VERSION     DAEPUT010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19883
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.076"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            216..1580
                     /locus_tag="KRL22_002882"
     CDS             216..1580
                     /locus_tag="KRL22_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBH1273333.1"
                     /translation="MDIKELVKMQRKYYNTGKTRNISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVSQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            1719..2885
                     /locus_tag="KRL22_002883"
     CDS             1719..2885
                     /locus_tag="KRL22_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1273334.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            3002..3784
                     /locus_tag="KRL22_002884"
     CDS             3002..3784
                     /locus_tag="KRL22_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBH1273335.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(3903..4556)
                     /locus_tag="KRL22_002885"
     CDS             complement(3903..4556)
                     /locus_tag="KRL22_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1273336.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(4580..5944)
                     /locus_tag="KRL22_002886"
     CDS             complement(4580..5944)
                     /locus_tag="KRL22_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH1273337.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            6601..8031
                     /locus_tag="KRL22_002887"
     CDS             6601..8031
                     /locus_tag="KRL22_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1273338.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            8134..9237
                     /locus_tag="KRL22_002888"
     CDS             8134..9237
                     /locus_tag="KRL22_002888"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH1273339.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            9252..9488
                     /locus_tag="KRL22_002889"
     CDS             9252..9488
                     /locus_tag="KRL22_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1273340.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            9505..10554
                     /gene="vorB"
                     /locus_tag="KRL22_002890"
     CDS             9505..10554
                     /gene="vorB"
                     /locus_tag="KRL22_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH1273341.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            10556..11296
                     /locus_tag="KRL22_002891"
     CDS             10556..11296
                     /locus_tag="KRL22_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH1273342.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            11299..11838
                     /locus_tag="KRL22_002892"
     CDS             11299..11838
                     /locus_tag="KRL22_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH1273343.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            11962..14061
                     /locus_tag="KRL22_002893"
     CDS             11962..14061
                     /locus_tag="KRL22_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HBH1273344.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKIDSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(14328..14843)
                     /locus_tag="KRL22_002894"
     CDS             complement(14328..14843)
                     /locus_tag="KRL22_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HBH1273345.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(14935..16146)
                     /locus_tag="KRL22_002895"
     CDS             complement(14935..16146)
                     /locus_tag="KRL22_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH1273346.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            16822..18264
                     /locus_tag="KRL22_002896"
     CDS             16822..18264
                     /locus_tag="KRL22_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH1273347.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            18306..18659
                     /locus_tag="KRL22_002897"
     CDS             18306..18659
                     /locus_tag="KRL22_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273348.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            18850..19671
                     /locus_tag="KRL22_002898"
     CDS             18850..19671
                     /locus_tag="KRL22_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH1273349.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKEYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
BASE COUNT         7561 a         2352 c         3381 g         6589 t
ORIGIN      
        1 ttaatttttt caataaggtt ataattttaa aaaatgttta ttttaaaata aactatttca
       61 taagcttact tatacttaat aaggggcttt ttttattgga agatttatgt tatattgaga
      121 tgaatttatt atgatataaa aaataatgtt aggataaatt taaatctttt tctaaaaatg
      181 tattagtata attcttaaag aaaggatttt taataatgga tataaaagag ttagttaaaa
      241 tgcaaagaaa atattataat acaggtaaaa caagaaatat atcgtttcgt atagaacagt
      301 tgaagaaact taagttagtt gtatcacaaa atgaagaaaa aatactttta gcactaaaga
      361 aagatttaaa taaatcggat tttgaaggtt ttatgacaga agtaggcatg ttttatagtg
      421 aattaaactt tgctataaag aatataagaa aatggagcaa aataaaaaga gttaaatcaa
      481 gtatggttaa ttttccatct atatccaaag ttgtttcaca accttatggt gttactctca
      541 taatgtcacc ttggaattat ccatttcaat tagcacttat accattagtt tggtcattag
      601 cagcagggaa ttgtgttata ttaaaacctt ctgaatattc tgtgtcaaca tctagtgtag
      661 ttaaagacat agttgaagat actttttcaa aagaatatgt tgcagttgtt caaggaagtc
      721 aagaagaaag tgaaaagtta ctattggaaa gatttgatta tatatttttt acaggaagta
      781 ctaatgttgg taaaataatc atgaaatcag catcagagca tttaactcct attactttag
      841 aacttggagg aaaaagtcct tgtatcattt taaaagatgc taatatagac cttactgcca
      901 aaagacttac ttggggaaaa ctaataaatg caggacaaac ctgcgtggct ccagattatg
      961 ttttagtgca tgaagataga aaaaatgagt taatagagaa aataaaatat tatactaata
     1021 aatattttgg agataatcca tgtaataatg agcaatttcc taaaatcata aatcagagac
     1081 attttaatcg aatattatct cttattgata aagataagat agtctatggt ggaaattata
     1141 ataaggagac attaaagata gagccaacta tagtagacaa tgttaattgg gatgataata
     1201 taatgaagga agaaatattt gggcctatat ttcccatttt aacatataaa gatttggatg
     1261 aagtaataca aaaaattata caaatgccaa atccattggc actttatatt tttacaaaaa
     1321 ataagtacct agaaaataaa cttttagaaa tgattccagc aggaggatgt tgtatcaatg
     1381 atacagttac tcatatagct acgaattact taccttttgg tggtattggt gaaagtggta
     1441 tgggctcata tcatggaaaa gctggattcg atacatttac tcactataag agtgtgttaa
     1501 aaaaattaaa tttggatgtc cctattagat atgctccata cgataataaa ttaattaagg
     1561 ttcttaaaaa gataatgtag gttatattgt agaataataa atataaataa aattgagtat
     1621 ttgtattctg aatatatttt atttttaatt tggtatattt gttataaaag tgatgatttt
     1681 gtgataaaat ttaattatat agaaataagg aggaaaaaat gaaaattaat tggaatacaa
     1741 aatacacaac aatagcaatt tatacattta taatagctgc tagtagtatt atattttatc
     1801 tagtatcatc acaaattgat gtattttcta ataatttaga tgctatattt acaacattac
     1861 aaccttttat aataggattt gctattgcat atcttcttaa ttttatttta aagttttatg
     1921 aagacagaat ttttataaaa agtgagaaat taaaaaaact aaaacaaagt tcaaaaagag
     1981 gcttgggtct tttattaaca tatgcaacag ctacattgat actttactta tttatgcatt
     2041 tcgtattgcc acaagtaatt gagagtattg ttggactagc aaatgatata cctatgtatg
     2101 taaacaatgc aactaagctt attgataaat taatgactga tttaaatctt gatgagcaat
     2161 actttaattt agcagttgat aagtggaatg agtttgttac atatattata aagtttgtaa
     2221 cagatttaat cccaatatta ggaagtatgt taaagaatgt agcctctagt atatggaata
     2281 ttgtactagg attaattgtt tcagtatact tattaattga taaagaaaaa ttctatggat
     2341 taagcaaaaa aataacttat gcagtattta cagaaaaaca agctgctaga attttagaat
     2401 taactcatag aagtaactat acatttggaa gatttttagg tggcaaaata ttagattcat
     2461 tcattatagg tattctaaca tttgtaatac ttacattagt taaaatgcca tatacattat
     2521 taatatcagt tataattggt attacaaata ttatcccttt ctttggacct ttatttggag
     2581 ctataccatc cacgctaata gtgatgtttg tatctcctat aaaagctttc tggttattgt
     2641 taattatatt aataatacaa cagatagatg gaaatattat aggacctaaa atacttggag
     2701 attcaattgg tatatctgca ttttggattt tgttctcctt attggttgca ggaaaattat
     2761 taggttttat tggaatggtt ataggagttc caatgtttgc agtaatttat tctataatta
     2821 aggatattgt tgaaagtaaa ttggacaaaa agggattacc gacagatact tccgattata
     2881 tgtagctaaa aaatattatg tataattaaa aatatataaa ttaagcaata tttaaagcac
     2941 tgagaaagtt aaactcttgg tgctttttag atataaaatt attatagaag aggtgttttt
     3001 tgtggcattt atagaatgta aatttaaatc taaatatact ggaggagaaa ctgatataat
     3061 tgtaattttg cctgtagcaa atggaaaaga actttttagt ggtaaagaga tatatgattt
     3121 tgaaggtaaa tttaaaacat tatacttatt tcatggttta gaagatgacc aaagctcatg
     3181 gattagatat actaatgtag agcattatgc taaaaataaa aatatagccc tagtaatacc
     3241 aagagtagaa actagttttt ataccgatat ggcgtatgga caccaatatt ttacttttgt
     3301 aagcgaggaa ttacctaaat ttgttagagc tatatttcct ttatcagata aaagggaaga
     3361 taactttgta gctggtatgt ctatgggggg atatggagct ttaaaattag cgctttcaaa
     3421 accaaaagag ttttcggcag ttgcaagttt ttctggttcg cctgatatga ttcatgagtt
     3481 agaaaatcaa caaatagaaa ccaatgcaga cattctattt cacgattttg gtagaccaga
     3541 agacgctaga aatagtgaga atgatttact ttacatactt aagaacctta aagaaagaaa
     3601 tgaagatatt cctaaaattt atcaattttg tggtgataga gattttttat ataaaaataa
     3661 tcagatgttt aaaaaatatg cagattctct gggtgtagat gttgaatatg aagagtgtgt
     3721 aggggggcat gaatggcgtc tttggaattt atggataaag aaatttatag atataattgg
     3781 atagtacact tatggtatta acaggtatac tataaaatat ctttaaatat gataaagact
     3841 gaaatcctaa aatcaaatta tgattttaaa atttcagtct ctaagaattt aataaaattt
     3901 tattaagttc ttacacgagt tattattgga gtaaaattgt caactatatc tatatagtat
     3961 ttactcaatt cctctaaaat ctcttcgcat aaatccgtac tatgaccaag attaataaga
     4021 aactgttttg taaaatgctt tattacagct tgagaagata tatcgtactt gtgtgaagta
     4081 taaactctaa ttatttcagg tttcatagca agtataccaa tacaagaaag tattaattca
     4141 tcatgttcta tagattcttt atcattaaca tatcttttca tgaccatttc ggttacactt
     4201 ctttgatagc ttaaaatagc ttcttcataa gctatatcca aataaaaatt tctatatgct
     4261 tcgtttttta gaaggaaaca aaggtcagca ttcatagcaa gaaagaacat catcatagta
     4321 ccttcttcat ggtagttata gattaaagac tgcatttcat ttcttatatc ttcatatatt
     4381 atagctccta tttcgctttt acttgagaag taatagctta ttagacctaa atttatatta
     4441 gctctttctg caatttgcct agttgttgtc ttatgataac cttgctcaaa aaataattct
     4501 ctagcagcac ttataatact agcttttgtt tctttgccct tttctgattt tgacatattt
     4561 actgtgtata cctctctttt caatcttttt ttgaaaattt gctaactata aatattgtaa
     4621 tagaaccacc tattatagga accaaaattc tgtcaaatac agtaagaata ccaatcatat
     4681 ttaataatgc caatataaca cttactataa cagcatagat agctcctttt tttgtagcac
     4741 ctttccagca aagaccaatt acaaatggtg caaatattac acctgtacat aatggagccg
     4801 gccaaaacaa taattctaat aaactatcaa atttaagtgc tatgattgca cctattatag
     4861 ctgtcaaagc tgatgcaatt tgagaatact ttagagtatt ttttaaatca ttaaattcta
     4921 tattaggatg taataatttg ttataaatat ctcttgatat aatagcactc attgatgtca
     4981 ttaatgaatc ggcagtagac attatggcag ccaatatagc agctaagaat aatacagata
     5041 ttaaaggtgg caaagtagtc gatatcattt gaggtaaaac ctgaacagat gatatgtttg
     5101 gaaataaact accaccaata gctccaatta ttcctatagg gaaagcaaga aataatagta
     5161 taaatcctgc aattacacta cttttaactg catttttagc attatcagca cattgatatc
     5221 ttaaaaaact ttcataagaa aatattgagc ctaaaactaa tggtaaaact gtatacataa
     5281 aatcactaat cgatttattt cctggaaaga atggttcttt taccattgat tgtaacataa
     5341 gtaaagggtt gtcgccaact aattttaagc ttatataagc tactattggc aaaaacacta
     5401 tacaaatagc aagttgaata aatgctgata ctgcaactcc ccacattcct gatgtataag
     5461 tatatataat gataactata actcctataa ttacagctat atcataagga ataccaaatg
     5521 cagtagatac agaaccaaaa gaaatcaatt gactacccat aatagctagt atagatattg
     5581 gtgttacaag actttgataa gctcttaaaa atacactatg accatatcta gtttcaatat
     5641 aatcagcagg tgttatatca caagataagc ttcttaattt tcctgcgaaa aatgcattta
     5701 taaagcaagc taaagctgca cctatagtag aatacattcc aacccaaagt cctctttcag
     5761 ctccccattg aactccacca actaagcacc ctcctccaaa agatgtagca gcaatggttg
     5821 cagctagtat aggcaaaggc agatttctac ctgcgattag gaaatcggat gctgttttaa
     5881 ctttttttga aaaataaaaa ccaatccata tgtatattgc acacgtaaca attaaaagta
     5941 acatagtctt ttctccttta taaaatattt taataaaata tacaaaatat atttaaaata
     6001 tattttatat aaaagtagta cgatatttgt tttattggtt ttagattaat atagctataa
     6061 taatttatga tattagatgg aaattacgta aaaatagaaa attgaaaatt ctgaaatttt
     6121 tgcatattga tatttatctc atagattctt ttttgtaatt gtaacacgct tttattttta
     6181 aatcaatagt acatgtataa aaataaaagg aatttaaata agaaaaagat atttttaata
     6241 tctggatgta gtatagaaat atcttgaata aattattctt gaataaaagt ataaaaaatt
     6301 aaaatcacta gaaatatgat aaaataattt aaaatacgca tttcaatgac atttcaaaac
     6361 aagaaaataa taaaaaacaa acctaaatta agtctaaata gctttttagt taattttagt
     6421 agtaaaaaat aaaacttaaa aagtgtttga caattatgaa ttttgagaat ataattaaat
     6481 taaaattata cacatataaa aatatgctct gaatcaagaa tgagatattt aagattcaaa
     6541 atatatatta ttatacgtga ataataaaaa gtaagaaaat tttataaggg aggggtagat
     6601 gtgagtagtc aagaaagcaa accaaaagga aatcttatat caaattttag agatgatatg
     6661 agagacccta agaaaagagc aatatacaca tattcaagtt ctataaactt agcgtacaat
     6721 tttataggtt actttgtatc aactgttaca aatatttttt taactgatgt ggcaaaactt
     6781 ggtgtaatta tggcaggtgg tatgcaaatt atacaatctt tcataaaaat tgctgtagct
     6841 cctataacag gtacagtatt tgacaaacaa ccattcaaaa aaggaaagta ttatccatgg
     6901 cttagatatg caccagcagc gttagcatta acatatggaa tatttttcat agttccatta
     6961 atgaaaataa gtccagcatt acttttacct ttgatgacag ctttattatt aatagcatct
     7021 tgtgctcagc aagtagtttt cactataatt tatgctattt accctgtagt tgctaagaca
     7081 cctagagacc gagttatagg ctcaactact acgaatatat ttaaagaagt tggtaaattc
     7141 ttagtaggtt tttcatatcc gttattatta gttttatttg cagatgtatt aggtggagaa
     7201 ggaatgggtt atttaggtac ctacttattc tttgcagcag gatgcctttt agtattttgg
     7261 ttttcttcaa cagagataat aaaatctgga gcagaagaag aagttcttca aaaagaagag
     7321 aagccaaaga ttaaagcaag tgaaatggca aaagctttat tcactaatgt accacttatg
     7381 atggcatttt gtttagaatt tcttatatgt ataagatcta taggattagg acctttggct
     7441 ccatattatt ttaaatatgt aatagaagat gaacgtggat tagcagtatt tttatcaatc
     7501 atgcctttgg taagtgtagc attcatgttt ttcgcaccag tgtttataaa aatctgtaga
     7561 gagcaaaaac tagcttcaat aatttctttt tctatatgtg cactatgcca cttattggtt
     7621 gcatggactc cttgggggaa aactacttta ggagtaacta tgttgttggc aattggtgga
     7681 ggtttttcaa atgtagtatc aataataaat cttaatttct ttgccggttc ttgtgattat
     7741 gggcattgga aatcaggaaa agacttacct ggcttaagta tgtcactata tccagttgca
     7801 atacaagtag gagtattact tgcaactact ataagaacag ttttaatgaa ctcaatggga
     7861 tatcaagctg atatggtagt cacagaagca gttaaatcag gttttataaa tatgatttct
     7921 tattctatgg caataccttt aataatagct gttgttatag caatactata tccagtaagt
     7981 gacaagaaat taaaccaaat aagagaagag ttaaatcaaa gaaatgctta gttaaaagaa
     8041 agttgagtag atggttaatt taagctatta aagtaagtag acgcaatagc gtttatataa
     8101 atgaaaatac atatacagag ggggctttta aaaatgatag aaaaattatt gagaaatacc
     8161 gtaaaagaat tacatcaata tgttccaggt gaaccaatag aaaaagttaa ggaaaaatat
     8221 ggtgtaaaag aaataataaa attagcttca aatgaaaatc ctctaggacc atcaccaaaa
     8281 gcaatagaag ctatgattga aatgttaaaa caaggtcaac tttatccaga gccagaagct
     8341 aacgaactta gaagaaaatt agctgaaaag ctagatttaa aaccagaaaa ttttattgtt
     8401 gctaatggtg cagataacgt tatcactcta ataggtgagg cttttataaa tagaggagat
     8461 gaagttatat attgtaaccc aacatttcca tcatatagaa ctgcaactat aaaaaatgaa
     8521 gggataccag tagaagtacc tttaacagaa gattataagt atgatttaca aggtatatta
     8581 gataagatta cagataaaac aaaattaata tgtgtatgta accctaataa tccaacagga
     8641 acaattgtgg atgataaaga gttagaagaa tttttaaaga aagtccctga aaatattata
     8701 actatattgg atgaagcata tatagaattt ttaacagttc ctaattatgt ggatggactt
     8761 aagtatgtaa gggaaaatta taacgttata gtaacaagaa ctttctctaa aatatatggt
     8821 cttgcagggc ttagagtagg atatggtatt gctaaagatg agataataag aactttattt
     8881 acagtaaaag agcctttctc tgcaaatcgt gttgctataa gtggagcaac agcagcactt
     8941 gatgatgaag agtttataaa agaaacatat gaattaaata gagttggaat ggcttacttt
     9001 aaggaagagt ttacaaaaat gggatttgat gttgtagatt cacaatcaaa tttcctttat
     9061 gtagatatga aaacagatat acctaagtta tttgaagact tgaaaaaaag agggtttgta
     9121 ataagaccaa gtgctacaca tgcacgtgta agtattggaa ctatggaaga aaataagaaa
     9181 tttgtagcag ttttaaagga aatattaaat attaaaggag agccaagtat tggataatag
     9241 atagaaatat tatgaaacgg ggtgtagata tgaacttaaa aataaacgca gagagatgta
     9301 aaagttgtga atactgcgtt atatcttgta aaaaaggagc attaaaaata tcaagtaaga
     9361 taaataaaga aggttatgct catgtagaag ttgatgagag taaatgcata ctttgtggaa
     9421 tttgctatca ggtgtgtcca gataatgttt ttgaaataat taaagaagaa gcatgtcaag
     9481 aggcttagaa ggagttggga taatatgaaa aagatgtgga aggggaacca cgccattgca
     9541 gaagcagccc taagaggagg ttgtgaattt tatgcaggat atccaattac accacaaaca
     9601 gaggtaatgg aatttttatc acatagaatg tctgaacttg gaagaacttt tatacagtcc
     9661 gaaaatgaga tggctgctat atatatggta tatggagcat atgcaagtgg aatgaggtct
     9721 atgacgagtt cttcaggacc aggaatatct ttaaaacaag aagggatttc ttacttatgt
     9781 gcaaatcatt acccttgtgt aatcgtaaat gtacagagat gggggcctgg tcttggctca
     9841 ttggactcag cacagacaga ctatctaaga gatactagag ggggaggaaa tggagattat
     9901 catttgatag tttatgcacc aaacagtatt caagagactg tagatttgat gtataactca
     9961 tttgatgtag cggagaagta cagagtgcct gttgaaattt tgacagaagc agctttaggt
    10021 caaatgatgg aaccagtaga atttccagag tttaagaaga gagaaggaga tttaggttgg
    10081 acttatgatg gaagtaatag agaccatgca aaggttgcag ataaccaaaa gccaactttt
    10141 tgtatggaga aacgtatgag aataactgaa aatgaacaac aatgggaaga ttatcaagta
    10201 gaagatgcag aatatgtgtt tgtagcgttc ggtataccat caagaacaac tatgaatgct
    10261 gttagaagac ttagagaaca aggtgaaaaa gttggaataa taagaccaat aacagtatgg
    10321 cctttcccat ataaagcatt tgaaaaggta agtaaagatg taaaaggatt tatctcagta
    10381 gaatcaacag acacaggtca attagtagaa gatgttgctt tagcctcaaa gaaagtatgt
    10441 aaagaaaatg tacctgtgta tggtttattt agtggaaatc atataccaaa aacattgcaa
    10501 gtaatggaca cttatagcaa aataaaatct ggcgaaatca aggaggtgtt ctaatatggc
    10561 tacagaaaaa ttaacaccta gcgttgtttc aataccaaac aagttttgcc caggttgtgg
    10621 tcatggaata gtaaatcgta taatagcaga ggtaatagaa gaacatggat atgaaaaaaa
    10681 tcatgtatta acattaggag ttggttgtgt ctgcaatatg aattttagct ggaatggtga
    10741 taagatgcaa actgcacatg gtagagcttc atctacagct ataggagtta aagtagcact
    10801 tccagataca ttagtaatga cttaccaagg tgatggagat gcttatgtta taggtctttc
    10861 tgaaacttta aatacagcat atagaaatca taatgtgact gtatttgtaa taaacaataa
    10921 taattttgca atgactggtg gacaaatgtc atggaccact atgccgggtc aagtcacaac
    10981 aacaagtgta aatggaagag atataaagac tactggtagt ccactgaaag ttcctgagat
    11041 ggtggcaaac ttctttgatg tagcatatgt agcaagaggt tcagttcata gcccaaagga
    11101 aataattaat ctaaaaaaat atataaaaaa tgcaatagaa gctcaattaa atggagaggg
    11161 atattcctta gttgaaatat tagcaccttg cccaactaac tggggtgtat cactagagaa
    11221 atctatcaaa tggatggaag aagaaatagt gccatattat gctcttggcg aatttaagca
    11281 aagggatggt gaatagttat ggaaaaagag ctagtatttg cagggtttgg tggtcaagga
    11341 gttttaactc ttggtctgat tgtagctgag tcagcacttg aattggggaa acaagtaact
    11401 tggatgcctg catatggtcc aactatgaga ggtggaaaag cctatagtgt agtaaagttt
    11461 tctgatgaga gtataggtgg gcctgatatg gaagaaatag atgttttagt agcaatgaat
    11521 aaaccatctt tagattatat aaatttagtt aaagaaggtg gaacagtagt tattaataca
    11581 tctgcaatag atgagaatgt aacattaaga gaagatataa gtgtagttaa aataaattgt
    11641 caggaattag ctcaaaaagt aaacaatcca aaagcagcaa atatagtagt acttggagca
    11701 ttaattgcta aaactgggtt atttgaaaaa gaattagctt taaaaactat gtgtgatttc
    11761 tttgaggaaa aaggaaaagg aaagtttaat gttcaaaatg aagcagcatt catggaaggc
    11821 tataataacg ccatttgata aattaccctt atcttaagtg atttatctca agatttaata
    11881 atctttagtg ccaagagaaa cttcatcttg agataaaatt cacttaaaat cacaactata
    11941 aacatatagg agcgtgaatt tatgagtttg gaaaaactta ttagaccaaa aagtattgct
    12001 atagtaggag tgactgataa acttggtttt ggaagaagtg cagcacttag tatagtaaaa
    12061 agtaaggaaa cagatagagt atattatgtt aatcccaaaa gagaagaatt gtttgggaga
    12121 aaatgttata agacgataca agaagttcca gaagtagtag actgtgtagt agtatgtacg
    12181 cctagaaatg tagttccatc tgtattaaaa gattctggag agttaggaac aaaggcagca
    12241 gtggtatatg ctagtggatt tgcagaggaa ggtacagagg aaggtacaga tttagaaaat
    12301 caacttatag aaatatcaaa tacatacgat atgaaaatat tgggtccaaa ctgcatgggg
    12361 ttgctaaatt gtatagataa ggttaatcta tgggcaggag gttctaaatg ggatttagat
    12421 actaaaaaac ctggtatagg aattgtaggt caaagtggat ttataactgc tgaaattgtt
    12481 tcaagtgatt attttaatat atcttatggt ttttcaacag gaaatggaaa tatagttaca
    12541 ctagaagatg cagtagattt ccttgtagat gatgattatg catcagtaat agcaatttac
    12601 cttgaaggtt taaaaaatcc tcaaaaattt atagatgctt taaaaagggc agcacaaaaa
    12661 agaaagccag taataatatt gaaatcagga aggtcagaaa aaggtgctat ttctgctgct
    12721 tctcatacag gaaatttagc tggttcgagt aaagcttttg aaagtatttt tgaaaaatat
    12781 ggagtaattt ctgtggaaaa tttagaacag tttatgtgtt tagcacaagc ttttagtgtt
    12841 ttagatggta atttacctgc aaattctaat tttgcagcaa taaacttctc aggaggagaa
    12901 aatactattt gtgcagattt agcagaagaa aatggtgtag aacttgcaga aatatcttct
    12961 gaaactaaag aagaaatgaa aaaatatctt ccaggatttg caacacctaa aaatccacta
    13021 gatgctacaa cagcattatt ccatgaaaag gatatgatag taggtttatt acataccttt
    13081 gaaaaggatg atagtgttgg atttactatg gtaggtgcaa atataagaga tgaagaaaat
    13141 gaaatgcatg aaaccctttg taaagctgta agtgaagcta gagaacaagg attgaaaaaa
    13201 cctgtgtttg cagttcctac acttgaagga aatagatatt tagattatag gactagatta
    13261 gaagataatc aagtgcctat aatgtcatca gttggaacta catttacttg ttttaataaa
    13321 atggctaagt ttatagatta tgattattca aaaagaactt tagaatttaa agctgttaag
    13381 aaaagagagt caaataatgt agtagcatta tcagaattag atagtaagat tgagatgaaa
    13441 aaatatggag taccagttcc aggacaaggt aatgcaaaaa gtattgatga attagatgaa
    13501 atcttaaaat atattaaata tcctgttgtt ttaaaaatag attcttctga aatattgcac
    13561 aaatctgatg ttggaggagt taaaatagga attaagaata gagatgaggc agtagatgca
    13621 tataatgaga ttttaactaa tgtaaaaaaa gcaaaaccag atgctaatat tgatggtata
    13681 ttagttcaag aaatggtaga aagtggtata gaaattatta ttggtataac taatgatgac
    13741 caatttggac caatgttatt agtcggttta ggaggagtat ttgtagaggt atttaaagat
    13801 actacattat atccattacc tataaatcat gatgaagcta ttatgatgct taaaaaacta
    13861 aaatcattta agcttttaaa tggctataga ggaagtgagc cttgcgatat tgatgctctt
    13921 gcagatatga tggtcaaatt aggaaaatat gcttatgaaa ataaggatga agtcaaggaa
    13981 atagacttaa atccagtgtt tgtatatcct aaaggaaaag gcgtatgtgc agtagatgcc
    14041 ttaatagtta aatataaata gtttataagt tttggtattc aaccataatt aaagcaccga
    14101 ctgaaaatca cattttgtaa gttagatagt gtgattttca gtcaccccaa atttaattta
    14161 aaaatatttt aaaatgaaag tatagtttta agtttcattg tgaaatagca ctgtataaac
    14221 aataaaatac tacgtataaa acgaataata aaaggtgttt taatgataag aatcaatctt
    14281 gattttcatt aaaacacctt ctttattata ttaaaaattt ttaaacgtta tattgtcaca
    14341 ggtgggtttg ttggagctgc atatgtacga ttagcaaatt cttggtcaac aaagaataga
    14401 ccaccctctc cagcaagttt aacacgtttt atattgtctt cacaatttgt ctcttcttct
    14461 gcttgttcag atataaacca aagtaagaat tgagaagttc taaagtctga ttcagagttt
    14521 gctacagctg ctaagttgtt tattaaagct gtaacctttt tttcatgagc taacgtacgc
    14581 tcaagaatat ccattgcaga agtaaagtct gaatctggca ttgggatagc atcaagctga
    14641 acctttcctc ctacattatg taagtatttg taaaaaaaca tagcgtggtc tgtctcttct
    14701 ttatattgaa cataaaacca attagaaaat cctttaagtc cttctgcttc aaggtaagaa
    14761 gacatagaaa gataaagata cgcagaatat aattcatggt taatctgctc attaagtaat
    14821 ttttccattt tagctgaaat catttttata cctccaaatt ttaaatgctc ttataaaata
    14881 taataatatt aaatggaaaa atattcaata aaagtgttta aatattttac atatttaata
    14941 aaaatttata ctaccattaa aaaaattata acttacaatg gctatagagc caattaatgg
    15001 tgcatttgct ccaaaatttg aatgccttac acttattttt ttatatttag aaaaacttgc
    15061 tgaagcagtc aattttttta ataatgtatt ttctataaat gtaccaggta tattaaagtc
    15121 atagcctatt attatagaac tacaatcaat caatgtaagt gtattaacta atgcatatga
    15181 tacgtatgta caaaattcat caagcaaaaa catggcaaga ctatctttat tatttgcctc
    15241 atctattaac ttgactaaag aaaaatcttt acagttaatt aatggggagt taggataaat
    15301 atggctcaat gattcaattc ttttaattag attactgaca cttgtataat aatctaaaca
    15361 tccattgtta ccacaactgc acaatggtcc actaaaatta attgatgtat gtcctatttc
    15421 tccactttgt cctaggttgc cagtatgaag tttattttct agaactagac cagctccaat
    15481 accattcatt atgtgtaggt atatataatt tgatatattt ttacctaaac catacatttt
    15541 ttctgctaat gcacctgaat tagcatcatt tatcaaaaat attggcaaat cagacatttc
    15601 ttttataaaa tctactatat ttaggtttga tacatttcca aaatctgggg gatttagtat
    15661 ggtaccattt atatcatcta ctggacctat tgaagaaata ccaattccaa ttatatctct
    15721 cttgttgatt ttcattattt tagtaaacat tctttttatt atatctttta aaacatcatt
    15781 tgatagacat ttggggtaag tttcagaaag ttgttttaca atattacctt ttaaatctga
    15841 aataattacc ttacatatat ttcttcttat taggattcca caaatacaag gcgatatatt
    15901 agaaatatct aataaaatag gtttacgacc tgatgaatgt gcatttaaag ttgatgactc
    15961 tatttcccta atcatatttt cattaataag ttcagtaact agatttgata aagtcatttt
    16021 agtaagtcct gtagacttag ctaaatcaac tctggacata ggtgtatttg tagaaagtaa
    16081 tttcaatatt attaacttat ttttaatttt tacatctttg atgttagaac cttgtttgtt
    16141 actcattata aatctcctta aataaagtta agtgttttat ttattttcaa gtatactatc
    16201 accttataat agagtaacat ttttttactt gaaaatatca ttaattagaa tatatcacat
    16261 tatatatcat aaaatatata aaaaaatgtt agaattaaat taaaagtgaa aagtagattg
    16321 atatataaat agtaaatact taattaaaaa aagataatga tagcaataat tattgttacc
    16381 aagaatctac tacttcaagt gttaccttag gtatttaagt tgatagtggt ttgcacgtaa
    16441 taaacttgat gtaatatata ttcttaataa tattgataaa agatttactt aaaaataata
    16501 tagattatgt aaacatataa tctatttatt gtatacaata aaatttcatt ttgtaaaaca
    16561 gtgaattaaa tatgtaatat agatatcgat ttttattaca aattgttact aaatataggt
    16621 acattagaac aaaaatctag taaattgtaa ctaaaatgta aatttttcct ttaatctata
    16681 caatattatg gaaacttttt gtaatttatg atataataac aaatatataa ttattaaatt
    16741 ataataaatg actatagcgt agatgtaata ctatgttata gtcatttttg aattaaactt
    16801 gatatatcaa gggggaagaa tatgagaaca attagaagag ttttagcatt aggattaaca
    16861 ttagctatat ttctaataaa tgtacctaat gtagatgcat taacatcaga tacaattaaa
    16921 ggtaacaata tatatgagac ggctggatta atagcagata aaaagagtta tgatacagca
    16981 attatggtaa atatggataa ttctatagca gatggtcttt cagcaagtgg tcttgcaggt
    17041 gctgttgatg ctccaatttt gcttgcacaa aaaaataaga taccaaatga aacaaaacaa
    17101 agattaaaaa atgttaaaaa gatatacata ataggtaaag aattatcaat aagtaagtca
    17161 gtagaaactg aactaaaaaa cacaggggca caggtaacta gattgggtgg agatgacaga
    17221 ataaagacta gttatagtgt tgctaaagag gtaaatggta tcaaaaaagt tgatgaagtg
    17281 atattaacta atgcatataa aggagaagca gatacaataa gtgctgcacc cgtatcagta
    17341 agagatatag ctcctatagt acttacagat ggaaagagtg tgcctttttc aacaagcaat
    17401 gtaaaaacat atgcagtagg tgggagtata tcaatgagca ctagtttagt taataaaact
    17461 aatgctaaaa gacttggtgg ttcagataga tatgatacaa ataagaaagt tataaaagag
    17521 ttttatccag atgcatcaga attttatttg agtgatggat atgatttagt aaatgcactt
    17581 acaggttcta caattgctaa ggaaaatcca attgtattgg tgtcagaaag tagtgataag
    17641 tctatattag caggagcaga taagattact agattaggtt caataagtga cagtgtgtat
    17701 aataagtgtg tttctgctgc acaaaataat ggcgattcgt ctacaaaagg tgagtcacct
    17761 atgaaaaatg agacaagcat attaggtcag ccaacagcta gtttagaagc gtgcttaaaa
    17821 tgggcaaaat ctaaaaaagc taatgattta tttatagagt taataccaat attatatgat
    17881 actgctgttc aggaaggtgt taatcctgtt ttggcagtag ctcaatctgc aaaagaaact
    17941 ggtttttgta attttggtgg agtattagat gcatcattta agaatccttg tggacttaaa
    18001 acttctgtag gtggttctga tactgataag aatgcccatt caagatttga tacttgggaa
    18061 gaaggaatat tagctcaaat tcaacattta tgcttatatg caggacaaga tggttaccca
    18121 ctttcaaatc cagtagaccc tagacatgaa aaatctttat ttggtaaggc taaaacagtt
    18181 gaaagtttat ctaataattg ggctggaggt caatatggac aagatttagt aagaatgatg
    18241 ggagaaattg aggcaacaaa ataattgaag attatcaaat atccaataaa taaggattga
    18301 ttattatgaa aaagagtaat atttttagta tcatatttcc tacagtcata atggtgctaa
    18361 tgtttttaac ttttgctaca gatatattta atattccaga tattcaatct aaaagtattt
    18421 ttgttgtggg aatggttttg atttttccaa tttctttttt gatacaaggg ataatttgtg
    18481 tattaaataa gactaattgg attttatctc ttattgtgtc tttagtaact tatatagtat
    18541 taatgtatat atttttaaat gattctgcat atatatatgt tttactttat acagcttttt
    18601 atatgattgg acatataaca gctaaactct attacaaaat taagactttt aaaaattaaa
    18661 ttgaagtata taaaagtaac attaggagaa gtatccttaa tgattttcta aaatcagaaa
    18721 taggtgcttc tcttttttgt aaaaataaaa gtatgtaaat aaaatttaac cattataatt
    18781 ttcttttaac aaatgtatac aataaacttg ttgtataatt aagatagata aaataaaggg
    18841 agggataata tgaatttaat agataatcat attcatacta atttttcaag tgatggaaag
    18901 gattccatgg aagatacaat aaaaaaagct ataagtattg gtgttagata tttgactttt
    18961 acagaccatt tagaacatga tgaagataga ggattttgca taaattataa tgactatgtt
    19021 ccagtattta ataagtttaa agaaaaatat aaaaaggaca tagagttatt actaggtgtt
    19081 gaagtgggtt acagaaaaca tctaaaaaat gaaatagaag aaataataaa ttctaatcct
    19141 tttgattttg tattgtgctc aactcataca attgacaatg tacctgttcc atcaaaggag
    19201 tattttaaag gtcttagcaa agaagatgcg tattataaat attttaatag catacttgaa
    19261 actaatcgtg aatttggaga ttacaatata tatggtcatt tggattatat atctaggtat
    19321 ggaatatatt cagataatag agttatatac aatgacttta aagatgttat tgatgaggtc
    19381 ttaaagtcaa taatcaataa tgggagtggt atagagctaa atacttctgg ttatagatat
    19441 ggactaaatg ctatacatcc aaatgaagat attctaaaaa gatataaaga acttggagga
    19501 tttatagtta ctgtaggttc tgattctcat agggtagaag atatatgcaa agattttgat
    19561 gtggcctatg atatgcttaa gtatcttgac tttaaatatg tatctttatt taaagaaaga
    19621 gaaacttatt ttgtaaatat agaaaaagtt aaatctaaca atatagctta gagtgtgttt
    19681 tgaagtaaat taatggatag ttaaaaagtt aatagttata atattgtatc ctctagaaaa
    19741 atactagagg tttttatttt gctaaaataa ctaaatagaa ttaaatttaa atagtatagt
    19801 ttattttaaa ttgaatagtt tattgttgat atattttact attatatatt tttattgtga
    19861 tataatagta aaatatatta acc
//
LOCUS       DAEPUT010000075        19621 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.077, whole genome shotgun sequence.
ACCESSION   DAEPUT010000075 DAEPUT010000000
VERSION     DAEPUT010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19621
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.077"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(260..1132)
                     /locus_tag="KRL22_002899"
     CDS             complement(260..1132)
                     /locus_tag="KRL22_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1273350.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(1526..2104)
                     /locus_tag="KRL22_002900"
     CDS             complement(1526..2104)
                     /locus_tag="KRL22_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1273351.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(2162..2878)
                     /locus_tag="KRL22_002901"
     CDS             complement(2162..2878)
                     /locus_tag="KRL22_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBH1273352.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            3069..4154
                     /locus_tag="KRL22_002902"
     CDS             3069..4154
                     /locus_tag="KRL22_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1273353.1"
                     /translation="MIIISRENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(4309..4968)
                     /locus_tag="KRL22_002903"
     CDS             complement(4309..4968)
                     /locus_tag="KRL22_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1273354.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(5185..6477)
                     /gene="lysA"
                     /locus_tag="KRL22_002904"
     CDS             complement(5185..6477)
                     /gene="lysA"
                     /locus_tag="KRL22_002904"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBH1273355.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(6495..7688)
                     /locus_tag="KRL22_002905"
     CDS             complement(6495..7688)
                     /locus_tag="KRL22_002905"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH1273356.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(8049..8666)
                     /locus_tag="KRL22_002906"
     CDS             complement(8049..8666)
                     /locus_tag="KRL22_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273357.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(8836..10536)
                     /locus_tag="KRL22_002907"
     CDS             complement(8836..10536)
                     /locus_tag="KRL22_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273358.1"
                     /translation="MKRYLKTYGVALIIVIIYSFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(10933..11496)
                     /locus_tag="KRL22_002908"
     CDS             complement(10933..11496)
                     /locus_tag="KRL22_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273359.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(11655..12368)
                     /locus_tag="KRL22_002909"
     CDS             complement(11655..12368)
                     /locus_tag="KRL22_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HBH1273360.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            12660..14324
                     /locus_tag="KRL22_002910"
     CDS             12660..14324
                     /locus_tag="KRL22_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HBH1273361.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKHFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(14431..15330)
                     /locus_tag="KRL22_002911"
     CDS             complement(14431..15330)
                     /locus_tag="KRL22_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBH1273362.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(15357..15995)
                     /locus_tag="KRL22_002912"
     CDS             complement(15357..15995)
                     /locus_tag="KRL22_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH1273363.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(16332..17330)
                     /locus_tag="KRL22_002913"
     CDS             complement(16332..17330)
                     /locus_tag="KRL22_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HBH1273364.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(17428..18003)
                     /locus_tag="KRL22_002914"
     CDS             complement(17428..18003)
                     /locus_tag="KRL22_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273365.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            18319..18582
                     /locus_tag="KRL22_002915"
     CDS             18319..18582
                     /locus_tag="KRL22_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273366.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(19019..19396)
                     /locus_tag="KRL22_002916"
     CDS             complement(19019..19396)
                     /locus_tag="KRL22_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1273367.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
BASE COUNT         6446 a         3209 c         2056 g         7910 t
ORIGIN      
        1 ataaaattaa ttttataatt gttaattaag gaaatgatat tgtttagaga aataaaaaaa
       61 gcactctcca tgaatggaaa tgctttcttt aataaattag ttgacgtagt aaagatgtat
      121 tcagaataca tctttatgtt ttgagtctcg aaatatttat ttgtattatt taaacgaaaa
      181 tttatttttt aagtgataat cgagtattta ctaataaggc tatgattctc aatttcatag
      241 ccttattaat atacaaactt tactcataca cagaatatct tttccaaatt tgctctaaat
      301 catcaaaatg ctgtttaata tcttcttttt ccttcatccc aacagatata gcaagggcat
      361 ttgaaatact aagagctgga actagagaat ctacaaatga agccatatta ctcttaacta
      421 gaagagtgtt atctgcaagt gatgctactg gcgcaaataa gctatctgtt aatgatatta
      481 catgggctcc tttttcctta gcataattga caatttgata agatttctta gaataacgag
      541 ggaaactaat agcaactatt acatcttctt catttattct tacaatctgc tcaaaagcat
      601 ctcccatatc cattctaatt atatgaacat tgtcaagtat tatatctaag taaaaaccta
      661 aatattgagc tactacaaaa gaactcctca ttccaagtat atatattttt ctcgctctta
      721 aaagtttgtt agaagcttct ttaaacgctc tctcgtcaat ttcttctagt gtagacctta
      781 tattatctat atcacttttt aaaactttgt ttagtattgc aaaatcatcg gaataatcat
      841 gtgccatttc aactctttgt actgtagtta gtttattttt tatgagttct tgaagtgcag
      901 cttgtaattt aggatatcca ctataaccta atgcatttgc aaatcttaca actgtagact
      961 cacttactcc tacagtttca cccaatttac atgcagtcat aaatgcaact ttatcataat
     1021 tatttaaaat gtattgtgct ataagttttt gacccttact caatctcgta tattgagatt
     1081 gtatatttga tatcaaatgt ttactgtcct tcatttcatt tgtttcttcc atttttttct
     1141 ccttttagtt atataaacta ttttgtttta ttaacactgt ctttttctct aaaaatttta
     1201 ttttttatct caatttcatc ttagttttta tcatagcttc ttaaactcat aaaattctaa
     1261 cttttctgta ccttatactt cacatagtat tttcgattaa atttattata ccatctttcc
     1321 ttgcattttt taatatttat ccaatatttc ttttaaattt ttcaattttt actcatttaa
     1381 aagttatcta tcttattttg catatttaga tgtatatttt gttttgagaa taagctgttg
     1441 tatacttatt atttaaagta tttttaatag gtcacactat atatattaac tcttaataca
     1501 atcttgtcaa gttttttagt atttattatg cttttttctt ttcaattaaa atcaattgtg
     1561 gtgggttatt gacttgattt aaaaacttag attctaaaac attaaattca tcttgattta
     1621 aattattgac aaggttatat atgcaatctt tttcttcttg acctccatca tgccctgtat
     1681 atatggcaat gcttattact ccattttctt ttagcatttc taaacttaac tttatagcct
     1741 ttaaagttgt atctggtttg gttataattg aatgtttcgc tcttggaaga taacccaaat
     1801 taaataaaac acatgaaact tcttctttta tatattgatt cattttttca tgcccatcaa
     1861 atatcaattt tactctatct gtatatcctt ctttctctag tttctttctt gtagacttta
     1921 ttgcttcttc ttgtatatca aaagcatata caaagccctt ttctccaacc ttctcagcta
     1981 gataccttgt atcataccca tttcccatag tagcatcaat tactatgtca ccttcattta
     2041 taatattttc taaataaaat ttatttatat ctgtaatttt agttaaatac tttgcatatg
     2101 ccataatact atttctccct actattaact ttatttcatt ttttctcaat ttatttttat
     2161 cttattttat tgattttaaa tattttattt catcttctgt taggtatcta tattctccaa
     2221 ctttggtgtc ttttaatact attttcccca cagaaatcct tcttaaattt aaaactggat
     2281 gatttatagc tttgcacatt tttcttactt gtctatttct accctcatgt atagttattt
     2341 cacacactga ataatttttt tctttatttt ctttagttac ccttattttg gcaggtgccg
     2401 ttgtgtaatc ttctattttt agtcctgttt cgaattgtct tatctcatca tcacttataa
     2461 ttcccttcac acttgccaca tacgttttat caatttcatg ctttggatgg gtaagcttat
     2521 atgttaaatc gccatcatta gtaagtatta ataatccact agtttcataa tctaatctcc
     2581 ctattggata tactctttcc cttacatctt taagtatgtc tattacactg ggtctattga
     2641 attggtcttt tactgtagtt atatatccct ctggtttatt taatactata tatatataat
     2701 tttcacttgg ttttactttt ttattatcaa attctactat gtctttttct tcatcaatat
     2761 taaaagataa ctcttttact acacttccat ttacctttat tcttcctcca agaattattt
     2821 cttctgcttt tcttcttgat gctattccac aagaagctat atacttatta attctcatac
     2881 ttaatccttc cttatcttaa attatgtgtg tttaatattc ttatcaatgt taattttgct
     2941 acattattat actatactag accttaatta aaaacaagca aaaaaattat ttaattttcc
     3001 taaataattg taatttcttt tcacatacta ttaatatgta atagctgact aaacactatt
     3061 ttaaggaagt gattattatt tcaagggaaa atataaaata ctatttaata gtcgtgttta
     3121 ttggaatttt attttttaaa tttattaata ctccatcaga ctttatatct agtattgaag
     3181 gattcttaaa gttttttagc ccatttttat tagctatttt acttgcttta cttttaaatc
     3241 cacttgtgat gctttttgag gtaaaattca aagcacatag acttttagcc atttttttat
     3301 cttatatatt tataggtttt attttagcct ttgccattag gttattaatt ccatcaatag
     3361 ctaatacatt aaatagattg ataaatgaaa tgcctatgta tactgattat atagatagtt
     3421 ttatagaaaa aaatatgtca aacatagatt ttctaaaaac tttaattcct catatacaac
     3481 atagtttaga taatttatta aaagaagcaa gtaattttgt tggtaaaatt cctaaaaact
     3541 tcttaatcta tacacttagt atatcttcta tgctatttaa tatgacaatg ggatttatac
     3601 tatctatata cattatatat gacaaagaaa aaattgcatt gggatttaag agatttctat
     3661 attcttctac tgctagaaac aaggcagata acattataga attttttagg actactcatg
     3721 atattttcta tgattattta cttggtagaa tattagactc tcttattatt ggtataattg
     3781 catttttagg atttcaattt gttatcagaa tagaaaatgc tttattttta gcttcaataa
     3841 tattcttagg taatataatt ccctattttg gtccttttat tggtgcaatc cctccaatag
     3901 ccatgactat attatatagt ccacaaaaaa ctatatgggt tattgcattt ctatttatat
     3961 tgcaacaatt agatggaaat tttatagaac caaaagttat gggtaatcaa gttggtatag
     4021 gagctatatg ggtaatatct gctattttgg tgggacaatc tctatttggt ttcataggag
     4081 tttttctttc agtaccaata gctgctgttg taaaaactta tgttgataaa tatatagata
     4141 atcgtttaca atagcttatc tctactgtga ctttaatttt tagtttaaaa tttaactgct
     4201 atttattaaa ttatttctca aaaaatatct cttagtaaga aaaaattgct aagagatatt
     4261 ttttataata tataatttgt tcattaaatt tatgcatata ttttatactt attgattatt
     4321 tgagttttga gaatttccac cactatctga accaccagta gtatcttgtg gagttggtgc
     4381 tggtgttgga ttactattat ttggcttttc ttgattttga gaagaactgt tattattgtc
     4441 agacttatta ctatctgatt ttttatcatt atttttagaa ctagatttat tatttttact
     4501 acttccacta taagaagatt tccttgcatc tgattcaact ctatacctat cttctccagc
     4561 cgtatctttt gcctttttct ttctttgttc ctctgcttcg ttttgttctt tttctaattt
     4621 agttaactct tctttctttt tagttgcctc ttctttaata acagaggaac catttttgat
     4681 tttctctata agtttaagtt ccttgattgc accctcataa ttttttaatt cttcaaactc
     4741 cgtcatattt gacattctca tagcttgcat atacatagct cttgcattct cattagtact
     4801 atcttcttcc agtgcagagg ataatgattc catagctttt ttatagttat gtttttctaa
     4861 atatgttttt ccttgctcta ctaaatttat ttcatctttt ttattaaatg aacatcctac
     4921 aagaaatata gataatatcg atattaataa aattactctt cctctcatta aatccctcct
     4981 tgtcatatac tttaaatttt atcataatta taaagttttt aaaatatttt atatttatta
     5041 caagaaattt gttagtaaaa caaaaaataa gcagatatgc tacgaacgat acaataaacc
     5101 aaaaattaat ttagagatac atatcctagc aaatctgctc ataataaact ttaatattta
     5161 atttttatta tatacttctc tattttatat ctctaaagct aataagtcct catagctttg
     5221 tctcttacaa attatcttat catttccatc aaatactgat accactgctg ctcttggtat
     5281 tttattataa tttgaagaca ttgaatatcc atatgcacca gttgatgttg ttataagtat
     5341 atctccactt ttaatatcca ttatgtttat atctccaatt aatatatctc cactctcaca
     5401 acattttcca gctattgtta catgattcat agcctcatga ttaattttat tcacaatact
     5461 acactcataa ctagcttggt acaacgaagg tcttacatta tctgtcatac ctccatctac
     5521 acttacataa accctaacat cttttatatc ttttatagaa cctactgtat acaatgtact
     5581 tcctgcattt gcaactattg atcttcctgg ttctattacc aatgtaggta cttctattcc
     5641 aagctcttta catgaagttt ctgctttagt gattatggtt tcacaaaact cttttatagt
     5701 tttaggttta tctccttcgc tataataaac gccaactcct ccacctaggt caatttctgt
     5761 tagttgtatg ttgaattttt cttttatttc ttttaccaag ttcatcatta tatccactgt
     5821 atctatgtat ggttctacat caaatatttg tgaacctata tgagcgtgaa gacctacaag
     5881 tttaatattt ttatattcac ttaatttttc tattgctcta aataaatctc catttactaa
     5941 agcaaatcca aatttagaat ctatctgtcc agtttttata taatcatgtg tatgagcttc
     6001 tataccagga gttattctaa agtatatctc ttgagtttta cctttatctt cacataatgc
     6061 ttcaagcaaa tctaattcat aaaaattatc cactacaaat ttacctacac ctaaatctaa
     6121 tcccatgttt atttcttctt tagtcttatt gtttccatga aagaaaactt tttccatagg
     6181 aaaatttgat ttataagctg tatataactc gcctcctgaa actacatcta aacacatttg
     6241 ttcttcattt ataagattac acatgtaaag aggtaaaaaa gctttccctg cataagcaac
     6301 cttatttttt ccctctctag ccttaaaata ttctatatat tctctacaat tttgtctaac
     6361 taaagcttca tcaaatacat aaagtggagt ttgatatttt ttactaagtt ctaaacaact
     6421 cactcctcca atatataatt catcattatt tacagtcata gttccatgaa gtttcataat
     6481 agcctcccca aattttatat attaaatact tctgctattt tttctatagc tacttgctta
     6541 tcatcagaat ttatagcaca agttatacga atctctgatg tagttataag ttttatcatt
     6601 ataccatttt cattgaatat cttaaatact ttagcagcaa ctccagaagt atttttcata
     6661 ccaagaccta ctaaagaaaa tttagtgata ttattatcaa tcactacatg ttcttcatct
     6721 gtatatttag atactatctt tttacattct cccaactctt cttttggaac tgtaaatgat
     6781 acacttatct tatctaaaat aggtgcagtt tggcttatca tatctacact tatacctata
     6841 gttgctatat cttcaaataa gctagatata ttttcagctt taaaatcttt tattgttata
     6901 gaactgtcat catcactagt agctaatcct gttattactt tatcctctaa tttcatgtct
     6961 tttccccctc ttatatatgt tcctttttct gtaccacatg tacgtccgac atagatttca
     7021 acaccatatt tttgtgcaag ctctatactt cttgaatgca ttacttgtgc tcctaaactc
     7081 gctaactcaa gcatttcttc atattcaatc tcatcaagtt tactagcctt tgaatatttt
     7141 cttgggtctg taaaataaat tccatcaaca tctgtatata tctcacattt tccatttaat
     7201 ttaaccgcaa gagctacagc agatgtatct gaaccacctc ttccaagagt ggttacatca
     7261 ccatcttcgt tgattccctg aaatccagtt actatcacga catttccttc atctaaacta
     7321 tttttaattc tgtttacgtt tatatcatca atttgagact ttccatgaag accactcgtt
     7381 tttatattta actgataagc attataactt atagctttac atccaagtgc atttaatgct
     7441 attgataata aagatgctga aatcatttca ccagtagaca ttaaagcatc taattccctc
     7501 ttactaggtt cattactcaa ttcctttgct aaagttatat attcatcagt ggattttccc
     7561 atggcagaca caactattac catttgtgga ttttcttttc ttcgttctat tatattttct
     7621 gctattgatt ttattttttc agtatctgct actgaacttc caccatattt ttgaacaatt
     7681 atactcatgc tttctccccc tcaagctaaa ttttgataaa taaaaacgcc caaaggtata
     7741 ctttggacgt gtaaatttca tagaccaagt aaccttgtag ctcaccactt taaaagtgac
     7801 agccttatgc atattctgca taagtccaga aaatttgtcc gtcaacaaaa tttcttcggc
     7861 tatataccct ttcatcaatt atcaacgctt accagctcct attgaatact attgaataca
     7921 gctacctcta ccctaggctc attattttta attaatttat taatatagtt ttatcatatt
     7981 ctatataata ttgcaacaat tattttacaa aatgtggcaa atcgatagtt ttcttttcta
     8041 aagttagctt atatacaatt aaatagttta tttaatccta aatctataaa atttatgcta
     8101 tactcattat catatctctc taaatcattt aattcggata gattatctgg tgtaactacc
     8161 aaaacgtttg gtactttaaa aaatggaatt gtagatttat ctattttttt agaaagattt
     8221 tcgtatttag aaatgtctat ttcattattt aagtcaacat caactaaaac ttgctttata
     8281 ttaccaaatt ggtctgtata ttcaataaat aaatcgtatt tcacatcatc tacactaaca
     8341 tttcggtaaa atctttttac atcacaacct gcagtattga ttctaacaac taattctgat
     8401 cctactagag cctttattaa atcatctccc ttaaaaagtt tactaccgtt taaatagtat
     8461 acataagaga ggtctttata attataataa tccacatcac aaggatattt ttttagtgta
     8521 tattcactac acatttttct caaagttttt ttaaaatttt ttttattgta tcttttttgg
     8581 tctccataaa tttttctaaa ttgagactct gtaacacatc taaccctgct aattaaaagt
     8641 aatatctctt tttccatatt cgtcatagta cattctcctt gaagtattat ttgcaaagtt
     8701 gtactaatat tatattaatt ttatgacatt aaatttacaa agaattaaaa taaaatagct
     8761 aatttttata gaattaaatt ctataaaaat tagctatcac tatgttaagt actattatca
     8821 atctttttat ttaaattata cattaccttg attttcagaa tctttggaat ctgtattttc
     8881 atcagttcct gttttttctt ttgctttttt atcttcaaag tttgcaatat ttaggttatc
     8941 aaattctgac atttctatta caccagattc ttcttttgaa tacgatattt tgactttatc
     9001 accaacctga gtcaatggca attcgctaga tacttttgaa gtagccctaa atattatatc
     9061 tttatttgaa tctaaagtta cataataatt agtgttacca cctcgcacat ctgggcttat
     9121 tcttgtcact gtgccttcta atacctcatc ttttaaatca ttatcaagtt ttaaatcatt
     9181 acccttagat tctaatgcat ccttatagtt tcttaatgct tcattcttat cttcacctat
     9241 tccaagtaca ttataatctt caacagatac aaatgcaact ctcttaacaa gaccagcctt
     9301 atcttttaat gatgatacat atgttggctg acccaatata ttatacatta cagggaacgt
     9361 agcttcataa tttttttctt gaacattacc ttcagctgat ttcattgcag ccgtttcagt
     9421 agctcctggt tgtttatata atctagcttc ttttgttcta gaatcaacta acataaatcc
     9481 aattgtagat tcatctccac ctgaagatgt tatacctgta taccaataag acctgttatc
     9541 attgccataa actaatgatg taccttctgt tggtactaaa actccctttt ctgatataac
     9601 agagtttaaa aatccattaa cataaacacc ccagtcttta atctggtctg ttacaaagct
     9661 ttgtggttgt attctatcca cccatttagg tgtgttttta acatcataaa catttatttt
     9721 tccagtttct gcatcaacag tggctattcc tgttgcattt gctcctccat agccaatttt
     9781 atgttcatat aaacttacaa cccaataagg tcttccttca tcatttattt caagagtgaa
     9841 atctgtcata ccaacattta caataccatg tatgtataaa tgtctttgta aatcctgatg
     9901 taagtaggct tctggttggt aaactatctt tattggcttt ccatctattt cttgaactaa
     9961 ttggacgtct tgaggattac tagctgatac ttttacataa ccacttgtac cacttagaga
    10021 tgttatccat ttaattatgt ctctgtgaac aagaggcgct acccagtaca actctccatc
    10081 tacattttgt atatgaaatt ttcctaattt ggatacactc cctattgcag gaacttctcc
    10141 aagctttttg tcacctaatt tcattgccat atcttcatct acaagacgaa tgtcatttac
    10201 actgacaggg ctaatgtcat cagtaaattt actttcagtt acttttccca atagttctct
    10261 atatgatttt gcatgaagta caggtgtaga agttataaag ggaactacta caatatacac
    10321 aagcaaagct attgctattg aaaaattata tttagccatt ttagatgctc tttcatttct
    10381 atctaacatc atatctagta ttcctgctac aacaaagaaa attattccta ctgaaaataa
    10441 agatgtaaaa tctaatctta gtacaggtaa tttaataaat gaataaatta ttacaattat
    10501 taatgcaact ccatatgttt taagatatcg tttcatttaa tactcctctc taaaaaatgt
    10561 tattattact attatatcca tatatttaca aaaaataaat atttatcata tttattatat
    10621 attaagatat ctttatatat ttatagttct gcttattcaa ctatatttaa cattatacgt
    10681 gtatgtataa atacttttta tacactgttt gtgctatcca tcccgcacct aaaggagtgg
    10741 gatttttgca ctattctgta ttatatatat ccaaaaatat tataaaaata caaatattag
    10801 cagaaattta aaaactgaag aaagtattct aactaagatt tacaaattct taatcctatc
    10861 gaagttaaac tactatcttc agcctaatta tctagcaata tttttttata tgaaaaactc
    10921 taaatcaagt ttttaaatgt ttgcgatttt tgatacataa gaatgttgtc tagaattata
    10981 ttctgataat aaaccttcat actctaaggt taagccagat aaattataaa aatcatttgg
    11041 cgttacttca aatgcttgtt tatttaaaat gtctatctca cttttttcta acatgtcagc
    11101 aacaaaattt gaacatacat atttatattc agattgtctc tgaatattca ttagtaaata
    11161 tattaatgcc attgtatcgt aatagtaatc ttctctataa tcactaatta attttatatt
    11221 tttatataga ttttcatatt gtaaattatc tacttctaac gaatataccc tacacacagt
    11281 gttttttctt atagcatata atccttgatt tatattttct tcaacaaatc ctccaataaa
    11341 tggattcctt ggatttagcc ttccaaaaga atacattggt tttagatttt catttaatga
    11401 tattgacaca tgtgtataca gctttttact tatattcctt attaagtaag ataatatagt
    11461 tcctgtatat gttgttacaa tatagacttt attcatcatt tccccccaat ctagtaacta
    11521 aataatatta tacacttaca atttaatatc ataagatatt ctaacataat aaatgtggtt
    11581 ttacaaattt tgattttaag gtactttaat attatataat ataataaaaa tataaatata
    11641 agttttctat atttttaacc aacagatgtt ttcttcaaat taatcagatg atttagtata
    11701 tcttgaacct ttccagagtc ctttaaatat cctaatgctc catttatttg tgattttaaa
    11761 tctatttcta cttccatatc caaatcaaca tttccttttt ttatagatat atttttaagt
    11821 gttattgggt aaagataact tttttccaaa gtaatcttat ttccattaac ctcaaatgga
    11881 acttttttat tgtagttact taatattttt tctagcattt tatcacttag tttaaatttt
    11941 ccaattttca cattctcaag acttacaact aagtttccat cctttaaagt aggtctcaat
    12001 tcaagttcat attgactatt taccaaacca aataccttat atggtcctgc tacctttatt
    12061 ttaccatttt tcatttcaac aaaattattt tcaagttcat taattccatg cttctgcatc
    12121 aatgtatata ttaaattttt aaactcttcc tctgaaacag atatttttcc aaccattcta
    12181 agtggatttt ttactacctc catagagttt atatatgagc cttttgataa atattcttca
    12241 tctatgattt tattattttg tgaactaaca tcatatcttt cttttggtgt caagatatat
    12301 acaacaattc ctgcaagtac taaaacaata acaattaaac ttaacaaaat ctttgcaacc
    12361 tttcccataa tcgtctcctt tacaaatctg tcatcagatt taaaataaat ttagataact
    12421 aacttcacat aatattctta acaatataca tactataata cagtctttta aaaattaatt
    12481 caaccaatct aatgttttgt aaataaactg taaaaacatg tttttagtat aaaagttaat
    12541 attttgcata atactcttaa ttacaccttt atttttttct aatcttggat taaaattaat
    12601 attatgcaat acagtgtagt gttctgtatt ataatcaaat taaataggag gtatagaata
    12661 tgtcaaatga aacgaactca tctaacttta taaagaatat tattataaat gaccttgaaa
    12721 caggaaaaca tgacagtatc ataactcgtt ttccacctga gccaaacgga tatttacata
    12781 ttggtcatgc aaaaagtata tgtcttaatt ttggattagc taaggagttt aatggaaaag
    12841 ctaatttaag atttgatgat acaaacccat taaaagagga tgttgaatat gtagagtcca
    12901 taaaagaaga tgtaaagtgg ttaggatttg attggaacga gttaaatttt gcatctaact
    12961 actttgatga aatgtataag agagctttaa tactaataaa aaagggtaaa gcttatgtat
    13021 gtgatttgac acaagaggaa atgagagaat atcgtggtac tctaactgaa ccaggaaaag
    13081 aaagtcctca tagaaacaga actattgaag aaaaccttga tttatttgaa agaatgaaaa
    13141 atggtgaatt taaagatggt gaaaaaacat taagagccaa aatagatatg tcttctccaa
    13201 atataaacct tagagaccca attatatata gaatatctca ttcaacacac cataatacag
    13261 gagataaatg gtgcatatat cctatgtatg cttttgctca tccaattgaa gatgcaattg
    13321 aaggaataac tcactctata tgtactttag agtttgaaga ccaaagacct ctttatgatt
    13381 ggtttgttaa agaatgtgag atggaaaata tacctagaca aatagaattt gctagactta
    13441 atataaataa tactgtcatg agtaaaagga aattaaaaca acttgtagat gagggtattg
    13501 ttgatggttg ggatgaccct cgtgttccta caatatccgg aatcagacgt aagggatata
    13561 ctgcagaagc attgcgcaat ttctgtagtg aaataggggt atcaaaagtt aactctacgg
    13621 tagatagtca aatgcttgat tatttcctaa gagaaaactt acaaccaaag gctcctctta
    13681 ctatgggagt tttaagacct ttaaaactta ttataactaa ttacccagaa gataagattg
    13741 agatgcttga aatagagaat aatgctaaag atgaatctca aggaaagaga ttagttcctt
    13801 tctctagaga attgtatata gaacaagatg attttatgga agaacctgtt aagaaatatt
    13861 ttagattttt cccaggaaat gaagtccgtt taaaaggtgc ttattttgta aaatgtactg
    13921 atgtaattaa ggatgaaaat ggaaatgtag ttgaaataca tggtacttat gaccctgaaa
    13981 ctaagagtgg ctctggcttt acaggacgta aggtaaaatc tacaatacat tgggttgatg
    14041 ctaaatcagc tataccatgt gaatttagat tatttgaacc attaattctt gatgatatac
    14101 ctgaaaatga aggtaaacat ttcttagaac aaataaatcc taattcattg gaaatattac
    14161 aaggttttgt tgaacctaca cagataaaag atgctaaaca ttttgataaa ttccagtttg
    14221 ttagaaatgg attctttagt atagataata aatatacaac tgatgaaaaa tttgtattta
    14281 atagaatagt tcctctaaaa agttctttta aaccaggtaa ataatcttac aatcaaaaaa
    14341 tgaagactta aaatataaat tacttctact ataaataaac ttagttagaa gtaatttttt
    14401 atttgagtct tcatcattta ctttaaatga ttaacttttt tcactacaga ttcccatgac
    14461 ttctattcca tcttttatgc attctatgtt aagaggaaaa tctggtcctt tttctccgtc
    14521 aatatctgtt ataagtgaat cttcacattc tatatgcacc tttttagttt taaagtatag
    14581 tatttcattt ccattatatt gatctaaata atcacctcta agcacactta tcaaaactgg
    14641 tattgatttt ggtattggca ttcctttaaa aataattaca tccaaatatc catcatctat
    14701 ttcagcctta tatgctagat ttatatttcc tgctgttttg ccattaaaaa tcaacataag
    14761 atacatatct ccatcataat acatttcctc agaagatact tttatcttaa atttcctcat
    14821 atacaatgct tcttctattc cctttatata ataagaaatt cttccaaatg aattttttaa
    14881 gtctgtgttt atcctttgtg atacatccgt aaacatacca gcacttgcaa catttataaa
    14941 gtacttatta ttgactttcc ctatgtctat tttctttggt tttgaattta tgatttcatt
    15001 tatagcttct tttatatcaa atgaaatttg aagagcattt gaaaaatcat ttgcagttcc
    15061 tgtaggcaaa attccaattg gaatttttat gtctaattct ttcattgcat ttactactaa
    15121 atctacagta ccatcaccac cagctatcaa tatgtgttca taagaactat caacttcctt
    15181 aaatgcattc tttacaggtt ctttaatagt taatctatag ggtatcaata aataattttt
    15241 ttcttgatat aattctatga tagtgtctaa atttgataat atcttttttt cacctgaatt
    15301 aggattgtat ataagtttta cttttttcat tatttctcct tactcatttt attcttttag
    15361 tatccaaaat cttcatttaa aaaaatcaca tgtattcttt ctggtgttaa ttgtcttttt
    15421 ataagtgtat aactacagca tattcttcct ggacttgaac agtctataca tataccagta
    15481 gtcttacatc cagtatttgt acttaatctt ttacaattgg ctggagcagc tattgttttt
    15541 gttcttttta tagcttcatc tacatcttta actattttat ttactcctgc tataactatt
    15601 actttatcag gtccatatat catagcagca accctattcc cattcccatc taaattgtaa
    15661 agttctccat cctctgttat cgcattagta cttgtaaaat aagcatctgc agaaaatgac
    15721 tttctatata tttctttcat ttcttctggt ttgatatctt ttgcatatct atcaagaaaa
    15781 ttatattttt ctcttataaa atcaatcact cctgtttcaa ataaggtcat agaacctcca
    15841 catcctacta gagaacctgc tttaactatt tcttcaattt ttttaagaag ctcttctttg
    15901 ttacttacta aatacccttt catattattg ttttccaaag attttattgt tttttctatt
    15961 cttttttcat taagccaatt taaattttga tccattttaa cttccccctt atttttaata
    16021 tgtacttaat tatttataaa ctttattttc tttataagtt tattttagta catctaaaaa
    16081 aaaatacaat ataaaactta aatagtttta cataattttt tccaaaataa cttactcaat
    16141 caaaaaagga aagtagatgt actattctac tttccctata ttgtatgtag tatttattgc
    16201 ctaaaatcta tatattaatt atatgtttca tattatataa tatcacagtt aattaaaatg
    16261 taatactatc ttctttttaa acatataaat tgtattatta aatttaatat atccaacttc
    16321 aataaatctt attaatttga tgaagaagat gctatagctg cacttgttgc tgccattaca
    16381 catgcaattt gaatagcaac aacaatattt aaaaatatat tattagttat agagcctata
    16441 ttattctcat ttcgtatcaa atctgcataa attgaagcta caatagcaga actaatcatt
    16501 actctattac tttttcctaa agaccaattt ccaaagcctt tttcttcttt aagtttattt
    16561 gaaacatttt ttatctcttc tattatttca tcttctctat aatctaataa tgaaattgct
    16621 cctattattg gatatccata ataattcatt ttacaatcat tttctttaaa tgctttttta
    16681 agttcaatag tctttttaca tttaagcata gttctatcat cactaaataa aagaatttgg
    16741 gataatgctt gtaaatcatt tcctttataa aaaccatttt catttagaaa ttcataacat
    16801 ttttctatgt attctaaatc ttcatctaaa ttttttgaat gaattgcaat aagtgctata
    16861 ttacaatagt catcactaga agttagaaat ggatgttttt tcctcatgta atcatatatt
    16921 attttcattt ttgatataca tgtaagataa tccattttct ctctattttc ataaactatt
    16981 gatgctgtaa gtggtaaata tgtatcgccc caaaactttt cacttttaag ttctttgtat
    17041 atatctaaaa tcatcttaaa actactttct ggatttgatt caaacgaaag tagtgttgcc
    17101 atataaaaca tattatatcc tctaaaatta gagaataatc cagtattttt tttaataagc
    17161 tctattcgtt cttccactaa tctaggactt attctcttgt tcttaagggt aaatgcaagt
    17221 gcacaactat gttgtatcaa tcccatttgc caagaacctt taacttcatt taatgctttg
    17281 taattttcta ttaataagtt tacttttcca tttataaacg attgttccat attgccctcc
    17341 tagtaatata tctcattgta ctaatagttt tatatttatt atatatatat taaatactac
    17401 aatcaataca tattacttca aagaacatca ttcttcaaca ataatgtagc cttttttgta
    17461 atgtcttccc atattattga ctctatcata gtactctgat tcactttcat tactccattt
    17521 gggcacaaat acatctattg cattagaatt actaaaatat ttactagacc ccctatccat
    17581 aacagttttt aattttccat ctacaataat cttagttcca aaacttaagt gattgtttgc
    17641 tacaaaacca tcttctaaat catctcctgt agcagttatc gctccatatc cattttcttg
    17701 attaagactt gtgtaataac taacttcaaa agttataggt actaacttct ttattttaat
    17761 acctaactga ttttgtagtt tctccttttg tactttcaac ttatactcat cactattttt
    17821 ataatcttcc ataccttgat tatacttgga attaaagctt ttacctgact ttactatagt
    17881 atctatattt actatagatt ctttacaatg atctgcatct atttttgttt ctccatttac
    17941 caataatgga gttaaacata cactacatac aacacatgta atcaatgctt ctttaagctt
    18001 cataaattcc ccccttatta ttttgatata ttagcatatt taatattata tgtctacatt
    18061 tagatttaaa taccacaccc atttgcttta agaagttgtc ttatatttaa ttcaccttaa
    18121 acacttataa atcctctatc ttagaatcat atagaataaa gcttttatct ttaaatattt
    18181 tttattaatc ttttaaaatc taaaactact ttatctaatt ttctcttttt tagaatttaa
    18241 gaattaaaat tctataattt taaaacatat tgaatttatt tttttgagat gatataattt
    18301 tcttaagagg tggttgatat gataaaaaat acaaaacaaa ttacagtaga agttaatgaa
    18361 attttattac aagaaatgtc taagataact aatgacgaaa ataatatttt gacagatttg
    18421 ataaatgaat caattgtaaa ttatattctt gaaaacaaaa aacataatat tgaaaataaa
    18481 gatttagaag aagtgattaa attttacaaa aaagaaaata ctgaaaaacc taaaagtgca
    18541 gcaagagcta tagctgaagc aaaaactcat actctgtatt aatcaaataa aaaagttcct
    18601 aaaaactagg aactttttta tattaataat tattaatata tctcaatatt tatctcaaat
    18661 ctatcaatat aagcatgttt aatacaatct attgtatact tatcttaccc tagaaataat
    18721 caaaacaaaa ataaaattat gccctttata tctaaaacaa ttaatttaca tgattaatat
    18781 acaaaaattc tgacttttaa attcgtatac aatatcaaac taaaataata ttaatgacaa
    18841 acccaatata aattaaattc aaacaggttt gattttacat caaacttatt gtattaatat
    18901 taaataacaa gacaaaaata tttataaaaa tcacaaattt tacataaaac tttatatttg
    18961 attcatttaa ctaattattg taaaaactat ttattttatg ataattaact acaccaaatt
    19021 attcatcttt tttaatatct ttaacccatt tttcaacaga gttcaattct tcttcattta
    19081 cccccttttt gaacaaggat ttcataaaac tctcaataga acttccatgc atattatcta
    19141 aaaaagtttt tgtttcaaaa tgtaaatact cttcttctcc aataagaact gtataatgtg
    19201 tatgtctatc aatttttctt gcacttaaga attgcttatt tactaatctt gataaaagtg
    19261 ttagtgttgt agtttgcttc caattatata gtttttccat agcttcaatg acatcttttg
    19321 atgctactgt aaaatctgaa ctccaaataa atttcatgac ttttaattct gctggtggta
    19381 tcttagtaat agtcatatga ttttacactc ctctcaaact tctacataat taaatactat
    19441 attaatagac ttttcgagtc aaaggtttta tttaaaatat ctcatccaaa tttattaata
    19501 caaaaaattt atatttttat tcaaaattaa acacacaatc tattaatata aagataaata
    19561 tctattctat aagtataaca gattatcaaa ttaaaattct aatatttgac ataatatata
    19621 c
//
LOCUS       DAEPUT010000076        19317 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.078, whole genome shotgun sequence.
ACCESSION   DAEPUT010000076 DAEPUT010000000
VERSION     DAEPUT010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19317
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.078"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(45..1238)
                     /locus_tag="KRL22_002917"
     CDS             complement(45..1238)
                     /locus_tag="KRL22_002917"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HBH1273368.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDIYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(1261..1926)
                     /locus_tag="KRL22_002918"
     CDS             complement(1261..1926)
                     /locus_tag="KRL22_002918"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBH1273369.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(1960..3072)
                     /gene="ribD"
                     /locus_tag="KRL22_002919"
     CDS             complement(1960..3072)
                     /gene="ribD"
                     /locus_tag="KRL22_002919"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBH1273370.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(3204..3325)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3514..5997
                     /gene="recQ"
                     /locus_tag="KRL22_002920"
     CDS             3514..5997
                     /gene="recQ"
                     /locus_tag="KRL22_002920"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBH1273371.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFINTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      6086..6197
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6339..7640
                     /gene="thiC"
                     /locus_tag="KRL22_002921"
     CDS             6339..7640
                     /gene="thiC"
                     /locus_tag="KRL22_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBH1273372.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDVVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            7694..7888
                     /gene="thiS"
                     /locus_tag="KRL22_002922"
     CDS             7694..7888
                     /gene="thiS"
                     /locus_tag="KRL22_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBH1273373.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNEYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            7881..8684
                     /gene="thiF"
                     /locus_tag="KRL22_002923"
     CDS             7881..8684
                     /gene="thiF"
                     /locus_tag="KRL22_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HBH1273374.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMPLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDIIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            8747..9517
                     /locus_tag="KRL22_002924"
     CDS             8747..9517
                     /locus_tag="KRL22_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBH1273375.1"
                     /translation="MDKLILGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            9534..10637
                     /gene="thiH"
                     /locus_tag="KRL22_002925"
     CDS             9534..10637
                     /gene="thiH"
                     /locus_tag="KRL22_002925"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBH1273376.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            10638..11327
                     /locus_tag="KRL22_002926"
     CDS             10638..11327
                     /locus_tag="KRL22_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH1273377.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKEFRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLVRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            11515..12909
                     /gene="yfcC"
                     /locus_tag="KRL22_002927"
     CDS             11515..12909
                     /gene="yfcC"
                     /locus_tag="KRL22_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBH1273378.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            13426..14793
                     /locus_tag="KRL22_002928"
     CDS             13426..14793
                     /locus_tag="KRL22_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBH1273379.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            14818..15426
                     /locus_tag="KRL22_002929"
     CDS             14818..15426
                     /locus_tag="KRL22_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HBH1273380.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMDDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            15474..15845
                     /locus_tag="KRL22_002930"
     CDS             15474..15845
                     /locus_tag="KRL22_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBH1273381.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            16024..16362
                     /locus_tag="KRL22_002931"
     CDS             16024..16362
                     /locus_tag="KRL22_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBH1273382.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            16828..17331
                     /locus_tag="KRL22_002932"
     CDS             16828..17331
                     /locus_tag="KRL22_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HBH1273383.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            17378..18337
                     /gene="moaA"
                     /locus_tag="KRL22_002933"
     CDS             17378..18337
                     /gene="moaA"
                     /locus_tag="KRL22_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBH1273384.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            18341..18811
                     /gene="moaC"
                     /locus_tag="KRL22_002934"
     CDS             18341..18811
                     /gene="moaC"
                     /locus_tag="KRL22_002934"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBH1273385.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            18847..19278
                     /locus_tag="KRL22_002935"
     CDS             18847..19278
                     /locus_tag="KRL22_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HBH1273386.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         7553 a         2066 c         3342 g         6356 t
ORIGIN      
        1 attataaaaa actacttagt agaaaaatat catcatataa tcatttatat aatatctaaa
       61 agatgtccca ttttatcttt tttagttttt aaatatagct tattaaagtc attaatttct
      121 tcattaatag ggattctatt ttcgattttt attccatatt tctctaattg atttatttta
      181 tctgggttat tacttaaaag atttatactt tttatgttta aattttttaa tatttgagca
      241 gccatataga aatctctcat atcttcttca aatccaagca ttaaatttgc ttcaacagta
      301 tcgtaacctt cttcttgaag tttataagcc ttaattttat ttaaaagacc aatacctcta
      361 ccttcttgct tcatataaat taaaactcca cttccatttt caacaatttt cttcatagaa
      421 gattctagct gtaatccaca atcacatttt agagagtgga acacatctcc tgttaaacat
      481 tcagaatgaa gtctaactag agtattttct atatttatat ttccataagt aagggcaatg
      541 tgttcttcat ttgaataaat atctctatat cctatgattt caaaatttcc atattttgtc
      601 ggaaggaaag cactagatac tttttctata gtagtttcat ttattttgcg gtattctata
      661 aggtctttta tagtgatgat ttttaaatta tgcttttctt tgaaaatcat taaatcatca
      721 actcttgcca ttgtaccatc atctttcatt atttcacaga taagaccaat ctctttaaaa
      781 cctgcaagtc tagcaaggtc tactgaggct tctgtatgtc catccctgac aagaactcca
      841 ccagtttttg ctattaaagg aaagatgtga ccaggcgttt tgaaatcttt acttgtagaa
      901 ttttcatcac agaataattt tacagtttca gctctttcat atgcagatat accagttaga
      961 gtatctgctc catctatagt aacagtaaag gctgtttgaa atgtatctgt attttctcta
     1021 accataagag gtatattaag acttttaaat tttttttcag tggcaggtag acaaattaga
     1081 cctctaccat atgtagccat aaaatttatt gattcaggag tagccatttc agctgccatc
     1141 aataaatctc cttcattctc tctactttca tcatcaacta cgattaccat tttcccattt
     1201 tttatatctt caatagcttc ttcaatagta ttaaacatgt aattcactcc tttattattt
     1261 ttaaaaacca tttttaaata aaaaatcttt atctatattt gatttatggt tactactatt
     1321 agaatttaat tccttgtagt tattagccat aaaattatta acatactttc caattacatc
     1381 gctttctaaa ttaacgaaat ctccaacatt ctttgtcaag agaatagtgt taattttagt
     1441 atgaggtata atagaaacct taaatatttc atcatctaaa tatgatatag ttaaacttac
     1501 accatcaata gcaacagaac ctttgagtat cattgaggat aaaagttttt tatcaggtcg
     1561 tatacttact aaaactgcat tttcatcttt ttcaaatttg cagatagttc ctttaccatc
     1621 aacatgacct gttactatat gaccaccaaa tcttgaagaa agactcatag ctctttcaag
     1681 atttaccttg tcatttgcat ttaataaacc taaatttgtg gaacgaattg tctccatcat
     1741 aacatcggct gtaaattcat tttttccgag gtttgaaaca gttagacaaa ctccatttac
     1801 ggctatacta tctccaagat ttgtgccatc taatatttta tttgatagta tggttacttt
     1861 tccactctta ccattagcag taatttttct aagtattcca acttcttcta ctatgccagt
     1921 aaacatccta acctcctata tgaatgtatt aacaaaaatt taatttaaaa catctgattc
     1981 tataagaata tcgccatcta tcaaagttac attattgatt gttaactgtg ttgaatctga
     2041 caaatgattt attccttctc cagaaacgaa tgtaggtgca tctttaccac ctataatctt
     2101 gggtgataga aataatttga ctttatcaac taacttattt ctaaagagac tgtcattgag
     2161 agtagcacca ccttcaacta gaacagaatc aatgtttaac tctcctaatt tatacattac
     2221 aaactccaaa tctactaagt tgttttttga aggagaaatt attgtttcaa cattattttc
     2281 ttttaacata gataatttta tactttcttt gcaacatgtg aaaactatag ttttactggt
     2341 tttatcttta accaaattac tattaagtgg caactttagg tgtgtatcta ttactattct
     2401 tgtaggatga gacacttttt cttgattgag cctacaagtt agtaaaggat tatcgttcaa
     2461 aactgtattt atgccaacca ttatactttg gtatttattt ctgtatttat gagttagata
     2521 ccttgatgat tcattagata tccattttga ttctagtgat tttgtggcaa ttttaccatc
     2581 tagacttact gctgatttta caatacaaag aggtcttttg ttttttatat gataaaaaaa
     2641 tgcctcattt aaatctcttg cttcatcttc taatattccc acagtaacat caatattgtt
     2701 atcttttaat ttttttactc cattaccaca aacaagtgga tttgggtcta atgtagatat
     2761 tacaactctc ttaatcttat tttgtataat tttatctaca caaggaggcg ttttcccata
     2821 atgagaacat ggttctaagt ttacataaag agtagagtct tttagacttt gtttagcact
     2881 gtttatagca tttacttcag catgattaga gccaaatttc tcatgatatc ctttgcctat
     2941 tatattacta tctttaacaa ttacacatcc aactaatgga tttggattta caaagccttc
     3001 tccattttta gccaattcaa tagctttttt catataataa atatcttttt ctttttgatt
     3061 cacaaaattc acaatatgta cacctcctgt ttaattggat aatttttaaa caaaaaaccc
     3121 tgagaattaa ctcagggttt agaataatct acaataaatg tttaataaat gtagaacaaa
     3181 attgctctac aaaaacactc attaaatatc ttcttccatc cagactttac tgtcggcttt
     3241 ggaatttaac caaatcaacc aagttttaca ttggctcgcg ggctataccg ccgattggga
     3301 atttcaccct accccgaaga ttaagtatta aatttatatt tagaatgtat cataaattat
     3361 tttactttgc aaactatttt tttaaaaaat atatgttaat atataatata gaatgtctat
     3421 aaactttgaa ataccacgat tgtgaatata aaaataaaaa tttgaacata atcaggaaag
     3481 aagtctaatt aatttaaatt aggagagtaa tatatgaata aaaaactttt agaaatacta
     3541 tcaaaatact atggatatac aagttttaga aaaggtcagg aatctataat aaattctatc
     3601 ttaagcgaaa aagatgtgct agctattatg ccaacaggag ggggaaaatc aatatgttat
     3661 caaattccag ctttgatttt agatggaatg acaatagtaa tttctccact tatatcactt
     3721 atgaaagacc aagtagatgc cttaaagact atgggaatta gtgctgcttt tataaatagt
     3781 tcattaagca gcaaagaatt taatgaaata ttaaataata ttagaaaaaa taattataaa
     3841 atactctata ttgctccaga gagattagat gcacaagagt ttattgagct aataaataat
     3901 aacaatgtaa gtcaagttgc gatagatgaa gcacattgtg tatctcaatg ggggcatgat
     3961 tttaggttga gttatagaag gatttctgat tttataaaaa atttgcctaa aagacctata
     4021 gttacagcat ttactgcaac agcttcagaa gaggtaagaa ctgatataat aaatttactg
     4081 tgtttagaaa atccagatta ttatataact ggatttgata gagagaattt atcaataaat
     4141 atagtaaaat catctagtaa aaataagtat attttagatt atattcaaaa tcataaaaat
     4201 gagtctggaa ttatatatgt tgcaactaga aaggaagttg aaaatatata taatggttta
     4261 tctaagagaa atatatctgt atcaaaatat catgcaggtt tatctaaaaa tgaaagaagt
     4321 aaaaatcaag aagattttat aaatgataat gtggatataa tggtagcaac aaatgcattt
     4381 ggaatgggta ttgataaacc taatataaga tgggttatac attacaatat gcctcaaagt
     4441 atagaaaatt actatcaaga aataggtaga gctggtagag atggagaaaa aagtgagtgt
     4501 gtacttttat tttctccagg agatgtacat atacaaaaat atttaattga tattggagtt
     4561 gaaaatcctg aaagaaaatt atttcagcat aagaagcttc aatacatgat tgacttagtt
     4621 tacagtaatt catgctatag aaagacaata ttgagttatt ttggagaaaa ttatatagac
     4681 aattgcaata attgtagcaa ttgtttagta gagggtgaaa tagtagataa aactatagat
     4741 gcacaaaaag tcatttcatg tgtagctaga atgaaaagaa gttatggtgt tactactatt
     4801 gtagatgtgc ttagaggttc taagaataaa aagattttac agcttggatt aaatactttg
     4861 tctacatata acattatgag agattattct agtgaagact taaagaattt tataaataca
     4921 ttggtttctc atggtttttt agatttagtt gagactctag gcaatggaaa tagaggtagt
     4981 tttcctacta taagattaaa tgagatgtct atgaaagttt taaaaggtga agtgaaagta
     5041 gagtttaaag aaattgttat gacaaaatca ttggaagtag aggatgagtt atataatgct
     5101 ttaagagaac ttagacattc aattgcaagt gaagaaagga tagctccata tatggtattt
     5161 ggagatggta cacttagagc catgtctagt agttatccaa ttaataaaga agaaatgcta
     5221 gatatctctg gagtaggaga aattaaatat caaaaatatg gtagagattt tgaagcagta
     5281 attaaagaat atgtcgaaaa aaataatata aataaaaaaa tagatgaaaa aaatgtcgat
     5341 tcaaagaacg ttaatagtga tttcttagag gttaatacag ataaagtttt atatgaaaaa
     5401 ctgttagtca ttagagaaga atatgcaaca aaggaaaaat tacctgcata tatgatttta
     5461 gccaataagg ctttgaaaga aataagtgga agatatccac ttgatgaaga acaattaaaa
     5521 gatatttctg gcataggtgg agtaaaattt gaaaaatatg gagctagtat tttggcagag
     5581 gttaataaat atgtaaaaga aaataatatt aatgttattt gggagaaaaa gggcaaaagg
     5641 aagttaatat tagatggaga aagtagaaaa aataatgaaa tagcattaga tttgctaaat
     5701 caaggaaaag atatacaaag tatcagtcaa gaaatagaag tttcactgtc aaccattatt
     5761 ggatatgtgc atgactatgt aaaggatgga catagtatat catttgaatt aggactagaa
     5821 aatttttata atgaagataa aaagaagatg attttagaag tttgtgaaaa agttggctat
     5881 gataatttaa ataacataaa aagaaaactt ccagattcaa taaagtatga aaatataaga
     5941 gctgtgatac ttgactctta tcttgaaaac ttaaaaaata atattatagc agagtaattt
     6001 ttaacttaat aaaaaataaa atttgtatta ttgtgttgaa ctaataattt tgctgtgtta
     6061 tactgaattt gtaaaaataa tgaaaaatta gagctagggg cgctagaatt ggctagctga
     6121 gagataaagc cgtaacttac aaaccctaat aacctgatca agataatgct tgcgaaggga
     6181 agctttttaa tataatttta ttatataaat aggcaaatta ttcaatgtta ggagaaattt
     6241 gtctaagtgt atatacgatt ataagagtgc tttccaaacg aggaaaagca ctttttttat
     6301 tttcaaaaac tataacttta atcttggagg attgtaatat gaactataca acacaaatgg
     6361 atgctgctag aaaaggcata ataactaaag aaatggaaat cgtttctcaa aaagaacagg
     6421 tagatgtaaa tgaattaaga gaattaatag caaatggaca agttgttata ccagctaata
     6481 aaaatcataa atctttaagt gcagaaggtg taggtaaaaa tttaagaaca aaaataaatg
     6541 taaatctagg aatttcaaga gattgtaagg atatagaaaa agaacttgaa aaggttagag
     6601 tagcaataga catgaaagct gaagctataa tggatttaag taattatggt aaaactagag
     6661 aatttagaga aaaggttgtt gaaatgtcac ctgcaatgat aggttcagta cctatgtatg
     6721 atgcagtagg atatttggaa aaagaattaa aagatataac agaagaagag tttttaaatg
     6781 taataagaca acatgctatt gatggagtag actttattac tatacatgca ggtcttacaa
     6841 gaagtgtttg ccaaaaaata aaaaatcatg agagattgac tcatatagta tctcgtggag
     6901 gttctttatt gtttgcatgg atggaattaa ataataagga aaatcctatt tatactaatt
     6961 ttgataaaat attggatata tgtgaagaat atgatgttac attgagttta ggagatgctt
     7021 gtagaccagg ttgtataaaa gattctactg atgttgttca aattcaagaa cttgtagtat
     7081 taggtgaact tactaaaaga gcatgggaaa gaaatgtaca agtaatgata gaaggtcctg
     7141 gacacatggc tattgatgaa atagaagcaa atgtagtatt agaaaagaga ttatgccatg
     7201 gagcaccttt ttatgttctt ggaccattgg ttacagatat agcaccaggt tatgaccata
     7261 taacaagtgc aataggagga gctttagcat gtgctaaagg agtagatttt ttatgttatg
     7321 taactccagc agaacattta agattgccta atttagatga tatgaaagag ggtataatag
     7381 ctgcaaagat agctgctcat gcaggagata tagctaaaaa tgttaaaggt gctcgtgaat
     7441 gggataataa gatgagtaaa gctagagctg atttagactg gtgtgagatg tttagacttg
     7501 caatagaccc tgaaaaagct aagagataca gagatgaatc aactcctact catgaggata
     7561 gttgtactat gtgtggaaaa atgtgctcaa tgagaacagt taagaaaata ttaaacaatg
     7621 aggaacttaa tctaatataa tttttggcta gtatgactgg aataaaaata agctgaaaag
     7681 aggaggtgat ttagtgaagg ttaatgggaa ggaaattgaa tttgaaaaag atttgactgt
     7741 tatagattta ttaaatgaat ataatttaaa aagtgataga gttgtagttg aagtgaattt
     7801 agagataatt gaagaatcta actacaatac atatgtatta aaagacgagg acattgtaga
     7861 gcttattagc tttattggag gtggttaaaa taaaaatatt tgtaaatgaa ttattaacag
     7921 atgttgagga aaatacaact gcttataaag ttagagatag ctataacaat aaatgtgatg
     7981 tattggtgtt aaatggatat ccaattaaaa cagatatgcc cctttgtgaa aatgataaat
     8041 taacacttat acaaaaagga gttaagccat cacttgatga attagaaagc ttgttgattg
     8101 ctagacatac tccaaatata cataataaat taaaaaaagg gaaagttgct atattgggat
     8161 tggggggact tggttccaat atagctatct ctttagctag aataggagtg ggagaacttt
     8221 tacttataga ttatgatgtt gtagaaccat ctaatttaaa tagacagcag tattttatag
     8281 atgatatagg aaaactaaaa actgatgcca tgatagaaaa tataaaaaaa ataaatccat
     8341 ttataaaatt aaataaacga gatatttttt taaacaagaa caatatggat attattaagg
     8401 attcagattt aataattgag gcctttgatg atgcttcatg taaagcacag gtatgtaatt
     8461 atgtattaat aaatttaaaa gataaatatt taatagcatc atctggtatg gcaggttact
     8521 atgattcaaa tataataact actaagaaga taaaagacag gttttatata tgtggggatt
     8581 ttgtgaatga agctaaattt ggtgaagggc ttatggctcc aagggttgcc atctgcgcaa
     8641 atcatatggc aaatttggca acgcaaatac ttatagatat gtaaatatta aaattagata
     8701 taaaaaagat tgaatattaa aaaaatttaa cgtggaggga aataatatgg ataaattgat
     8761 acttggtgga catgaattta atagcagatt attggttgga acaggtaaat atggttcaaa
     8821 taatatattg cctgaggtaa taaaagaaag tggaagtgaa ataataacaa tggcacttag
     8881 aagagtggat ttagacaata aacaagaaaa catattaacg tatattccaa aagagatgac
     8941 aatacttcca aatacatcag gagctactaa tgcagaagaa gctgtaagaa tagctagaat
     9001 atctagaaaa atgggatgtg gagattttat aaaaatagaa gtaatatcag atactagata
     9061 tttacttcct gataatgaag aaactataaa agctacaaag atacttgctg atgaggggtt
     9121 tatagttctt ccatatatga caccagacct ttatgctgga agaagactta tagaagctaa
     9181 tgcagcggca gttatgccac ttggagctcc aattggttca aatagaggtc ttcaaatgaa
     9241 agaaatgata agaataatga tagatgagtt ggatatacca ataatagtag atgcaggtat
     9301 tggaaaacca tctcaagcta tggaggctat ggaaatggga gctgatgcag tacttgtcaa
     9361 cactgctata gcttcagcag gagaccctgt acaaatggct agagcattta aattagctgt
     9421 agaaggtgga agagaagcat atattgcaaa aacaggaaat gtgtcagaat ttgcaaatgc
     9481 atcttctcct ttaacaggtt ttttaggcaa tttatagaaa gtggtgattg gtgatgagtt
     9541 tttatgatgt aatagaaaaa tatagggatt ttgattttga tggatattta aataatgtta
     9601 ctgataatga tgttttaaga agtttatcaa aagacaagct tgaagatttt gatatattaa
     9661 atttgctttc taaaactgca gtaaaacatt tagaagatat ggcacaaaaa gcacataaat
     9721 taagtgttca atactttggt aaaacagtat gtttatatac accaatgtat atagcaaatt
     9781 attgtgttaa tcaatgtgtt tattgtagct ataatataaa gagtggaata aaaagaaaaa
     9841 aattaactat ggatgaaatt agagaagagg gagaagcaat ttcaaaagaa ggtttcaaac
     9901 atctacttgt tttgactgga gaaagtagtt ttcactcaag tgtagaatat ataggtgagg
     9961 ctatagaaat attaagagag aaatttccct ctataggtat agaagtttat ccaatggaag
    10021 tagaagaata taagtacatt gtagataaag gtgttgaagg attaacagta tatcaagaaa
    10081 cttatgacga ggaaatatat aagagagtac atataaaagg cccaaaatca aattataaat
    10141 ttagactaga tgctcctgaa agaggggcaa aagcaggtat gaggacttta tcaataggtg
    10201 cacttttagg gctaaatgat tttagaaaag aaactttttt tacaatattg catgggaaat
    10261 acttaaaaac gaaatatcct catattgagc tttcatattc aacaccaaga atgagacctt
    10321 ttaaagggtg ttttgaggaa ttggtagata taagtgatac tgatttagtt caagctatgg
    10381 tatgtatgag attatttgac cctcatgcag ctataaacat atccactaga gaaaatttag
    10441 aaatgagaag tcatataata cctttaggag taactaaatt gagtgcaggt gtatctactg
    10501 atgtaggagg tcattctcaa gatgaacatg atactgctca atttaagata aatgatgaaa
    10561 gtactgttaa agatgtggag aaaatgctaa actcaattgg ttatcagcat gtgtttaaag
    10621 attgggaaag attttaaatg tatctgataa caaacagaaa attatgtagt gaggaacgat
    10681 atttagaagt tattaaagag tctatattga gtggtgtaga aaatataata ataagagaaa
    10741 aggatttaga atatcaagag ctaagaaaat tatatatgaa aataaaaact aaaatcaatt
    10801 gtatagattt tcaagagcaa atatcagatg aaagtttgaa aactaatata aatcaaaaag
    10861 agtttagaaa taaattcaag gttaatttta taataaatag taacattgaa ttttttgaaa
    10921 aagtggattg tcaaggtatc catcttcctt ttaaattatt cttgaattta attgaaaata
    10981 agtataattt taatgaaaat aaaatactag gattatcttt acataaagta gaggaagtag
    11041 attatttaga aaaattagta agaaatcaaa atataaaaat agattacata acattatcac
    11101 atatatatga aactaaatgt aaagaaggat taaatccaaa aggaattgag cttttaaaag
    11161 aagctaaaaa gattactgat attaaaataa ttgcacttgg gggaatttta ccatctaatg
    11221 tcaaggaaac attaaaatac tgtgatgatt ttgctataat gtcaactata atgaggtcta
    11281 aagatattaa aaaaaccata tcaaattata atgaaaagtt gaattagcaa atatagtata
    11341 ttgaattttt aacttaaata aaaataaaaa agttatcttt taaattttaa aaggtagctt
    11401 ttttatttta tatctttgct aataaaaaat tgtaaaaagg gaaaacttta gtcagagaga
    11461 ttaaacaata tcctagaaag atttaaaatt tagtaaagta tggaggacat tataatgact
    11521 gacagtaaaa agaaacgatt tattatacca cacactttta caataatatt tttactaata
    11581 gtcttgatgg caatattgac ttggatagta ccaagtggtg aatttagtag agaagatgta
    11641 gaaggtagaa tggtagttgt accagggact tatcaaagtg tagaaagtaa tcctcaagga
    11701 tttgcagatg tttttaaagc accaatagaa ggctttatcg attcagctga agttgtaggt
    11761 tttgttttaa tagttggagg tgcttttggt attgtaaata ggactggagc tatagaagca
    11821 ggaatagctt cggttatctc taagtttaag ggaaaagaac ttcttataat tccaatatca
    11881 atgattttat ttggacttgg aggtacaaca tttgggatgg cagaagagac attaccattt
    11941 tatatgatat ttgttccact catgacatcc ttgggatatg attctctaac agcaatagca
    12001 attgtattta taggagcagc agcaggagca gccgcttcaa caataaatcc attttcagtt
    12061 ggtattgcac aggcactagc tcaacttgct cctggttcag gagtaactta cagagtagtt
    12121 atttttatag catatatact aataagtata gcatttgtta tgtactatgc taagaaggta
    12181 aaggaaaatc ctgaaagttc aatagtatat gaaatagata aaaataataa atcaatactt
    12241 aatcaaactt caacagaaat aaaagaattt acttttaaag aagtatctgt tcttgctata
    12301 tttggaatag ggatggcaat aatgatttgg ggtgttttaa gtcaaggatg gtacattcca
    12361 gaaatatcaa tgtgttttgc tgcaataggt gtgctttctg gattggttgg tagattatct
    12421 caaattgaaa tctcagaaag ttttatagat ggagcaaaag atttagcatc tgcagctctt
    12481 gctatagctt tggctcgtgg aatcgtaata attgctcaaa atggatttat aatagatact
    12541 atattaaatt ccgcagcagc ctttctaggt gggcttccaa aggttatatt tgtatattta
    12601 tcatttttct tggaagctgc attggcattt ttaattccat catcttcagg tcttgcttca
    12661 cttacagtac ctgtacttgc tcctcttggt gatttggtta atatatcggc tcaagtgata
    12721 gtaaccgctt atcaatttgg tgtgggtctt acaaacttta taactccaac ttcaggagta
    12781 ctgatgggag cacttgcagt agcccatatt ccattttcaa aatgggtaag atttataatg
    12841 cctatcttgt tgattttgac agctgtatct ctagtctttt taacaatagg tatttatata
    12901 gggttttaat taagtgtagt tttatttaag atatttagta atggtataaa atgataatat
    12961 gttttcaata aattgccact aatttaatta gtggtaattt gttttttgta tttaaaaata
    13021 aatgtattta cttgtatttt gaattaatat ctacttagac attgttttaa ttgttatatt
    13081 tttatttaat taagcattga tttatcattt tttatatttc atataacaat gcaaaaaata
    13141 atttttatat agtaaatgac aaaagtttac aataaatgta tattttctta ctcattcctt
    13201 aaaattactc atttagttta ataactctca tttcatatgt aaagttggta aaaaaattaa
    13261 aattaaaagt aaaaaactaa ataaattaat gttaatttga aatatatatg aaggtttttg
    13321 gagaatactt acttatgata ggaaaaaatg ttaaaataat agtgtaatca aatataaagg
    13381 actgaaataa ttaacagtta ttaaatatta ggagtgtaaa aatttatggg attaaaagaa
    13441 tttgatttta ttgaagagtc tattgatatg ttgaggacaa tgtcaccaac attagaaact
    13501 atatcagatg aaatagaaga atattttgaa aatatcttgg atgaaaagaa tcaagaatat
    13561 ataaatgtaa cctctagaat aaaatcagaa tcaagtttaa gagaaaagat aattagaaat
    13621 agatatttaa aaaaatatgg agaagcaagt aatcttattc ataatgtttc tgacttaata
    13681 ggcctaagaa ttgagtgtag atttattgag gatgaaaaca aaatatatag acttttgaga
    13741 agatatttta ataaaacaga tgacaaaata aactattata ataaagagaa taagaatatt
    13801 aaattaaaac tatctgagag gcaacccaat aagcaaaaaa atggatttga aatatataaa
    13861 atagatggag tttttgcgta tttagataga gaagtaaaat ttgaacttca aattaaatct
    13921 cttgtaaatg tgttttggag tgaaatagaa cataaaataa tttataaaaa caatacatat
    13981 ttacttgctg ataaatttat aaaggatatg atggactcta taaagaataa tcttactatg
    14041 atagataatc agcttttaag tatttataaa aactttcatt cagggaagtc ttttaatatg
    14101 aaagtaagta aaaaagaaat tgaaaaatta tttgcgaaat tagtctatga cgctttttct
    14161 gaaaagatga ataaaagtat aggttttgtt gtagatttta aaaaaccatg tgagactata
    14221 ttgaactatt cttttaataa gcaagatata agtgatgaag ttttaggtaa ttttatgctt
    14281 gatgagtttg caagattaaa tgaaattgta aacaaggata tagattttaa tgagcaaata
    14341 gaatttgaaa gagaaccaac atttgatgat aagttttgta aagacctagg aaatcatttt
    14401 agaagtagat taaacacaga atttccatgg aacctatttt ttagaatatt atttgaaata
    14461 gagccatata acaataccaa agactttgaa aactttgtag agtttataaa agaaaatgtg
    14521 ctactagaag aaaataggga gcaattatta tgccaatttg aagaagatag caaacttata
    14581 attgaagata tatatgattg tatatttaat agtataagtg agattgatag tgttgaaatt
    14641 ttatataact ataatcttga aaaaataaac tttacatcaa gtgaaatcat aaattgtata
    14701 tgtagagaat atgagtgtta tggtgaatac ttagaagaaa aagaaaagct tatgaataca
    14761 tttaaagaaa agattattca aatctttgag taataggtta atgctgaagt ggcgctaatg
    14821 cgccattttt caaatatata tgaattaagt aaaattattt tggaggaggc gatttgtata
    14881 gagaaaacag gtgtaatttt ggcaggggga agaaattcta gaatgggtag agataaagcc
    14941 tttttagagt tacatgataa gctttttatt gaaattgcaa tagaagcatt taaaaacttt
    15001 gatgagttga taataatatc taataatgaa gaattatatt ctaaatacga tattaaagtt
    15061 tataatgata tagtaaaaga tgttggtcca attggaggaa tatatactgc tcttgaatat
    15121 gcaaagtatg atatagttac aattgcatgt gatatgccat atctaaataa tcaaatagtc
    15181 gaaagaatag ctaataaaat ggatgataaa agtgtgattt cagtgacaaa tggaaagtta
    15241 caaccattgt gttctggata taaaaagagt ataataaata aagtatcttt atgtataagg
    15301 gaaaatgatt taaagctcag aagctttata gataaaatag ataaaagtta tatatacttt
    15361 gatgaagaag atttattttt aaatgtaaac actgttgatg agtatgaaaa attaactaaa
    15421 gtttaattag ctatggttgt aaaatagagt aggatttata tggaggagag tttatgaatt
    15481 tacttaaatg cgattcttgg gcagtaatat taaataatag cgataaagaa agtaaagcat
    15541 ataaaatatt agatgaactt aaaaggaata tgtacaaagt tgttgctata gatgaagaga
    15601 aaaaacctat tgaaggaata gatgtgtatg aatgtttaaa agatgttcca cacaatattg
    15661 atgttgtagc tattattgat aaacaatcta agatggatgt gattttagaa gaagtagagc
    15721 ttttggatat acaaaatatg tggtttgaaa aaggaagctt tagtgaaatg atgattaaaa
    15781 agactaaaga tttaaaatta aatatagaat ataatttaag tttatatgat gagttgacta
    15841 gataaaatta tatatcttaa taataaaaat ataattagtt aataaaacat attattttat
    15901 agtatagatt ggttaataaa agtacagatt ggttaatgaa acattaaatt acaatatttg
    15961 ttaaaaaaat tgtgagttac atgatataat gtattaaata ggatactaag gagttgatat
    16021 attatgttaa tagtaactac agaaaaagta gaaggtaaaa agatatcaaa ggttttagga
    16081 ttagtgagag gaagtacaat aagagcaaaa catgttggaa aagatatagg agcaagtttt
    16141 aagaatcttg ttggaggaga acttactgga tataatgaaa tgctcactga agcaagacaa
    16201 attgccatag gtagaatggt tgaagatgca gaagctaaag gtgcaaacgc agtaatagca
    16261 tttagactgt cttcagcttc agttatgcaa ggggcagcag aaatgcttgc ttatggaaca
    16321 gcagttgttt tagaagatga taatagtatt cttgaaaaat aaaatataaa tagttaaaaa
    16381 gaggcatctt ttaaaaattt tatggatgcc tttttttatt tgaaaaaact aatttgagaa
    16441 gaaattttaa ctattatgac aataaaatta gggtgatatt atataaataa gtaaaattat
    16501 attatataat gtatggtata gactttaaaa attttatttg tagagaaaaa tatggacaat
    16561 gttataataa ttatagaaat taaaagtact tacattcatt atgtatgtga catgtataat
    16621 tagttttata tttaatacag ttttgaagta atatcttcat tttgagaacg ttggaataat
    16681 aaaaaatgta ttattatagg tgatataaat aaaaaataaa tataatatgt tatattgctg
    16741 atagaaaaga gaataaaaga aaataggttt tattaaaaga gatttttatt tataggactt
    16801 aatcaatgta tagaggggtg agaacatatg tttaatgttg caattataac acttagtgat
    16861 aaaggatatg aaggaaaaag agaagatata acaggaaaaa agttaactga atttgttgaa
    16921 aatacaggag cttataaagt tactgaatat gtacttataa aagatgataa ggaaatgcta
    16981 aaggaaaata ttataagact ttgtaatagt aataaaatag atttaattct tacaaatgga
    17041 ggtactggtt tttcaaaaag agatataacc ccagaagcaa ctaaggaagt gttggaaaaa
    17101 gaaataccag gtctgagcga atatatgaga atgaaatcca cagaaattac taaaaaggcc
    17161 atactaagta ggggtgtaag tggaataaga aataattcta taataataaa tttacctgga
    17221 agtcctaaag gtgcagttga aaatctaagt tttataattg atgttttaga ccatggcata
    17281 gaagttttaa gaggagaagc tacagaatgt gccactaaaa aaagtgaata gtatataatc
    17341 tagatagata aaaaatagac aaagaggtag ataaagtatg attgataagt atggaagaaa
    17401 aatagactac cttcgtattt cacttacaga taagtgtaat ttaaggtgtg tctattgtat
    17461 gccaccagat gtaaaatttg ataaaaatta tataaatgaa aatctaagct ttgaagacta
    17521 caagtttatt ataaaggcta tggctgaaca aggtataaca aaaattagat ttactggagg
    17581 agaacctctt ttatatccta aattaaatga gcttataaaa tttacaaaag aagaatgtgg
    17641 aataaataac ataggaatga ccactaatgc tattggtctt tctgatagaa tttttgagct
    17701 tgaaaaatgt ggcttaaata aagttaatat aagtttagat tctttgaagg aatataagta
    17761 taaatccgta acaagaggag gaaacttaaa agatgtctta aaatcgattg aatcttgttt
    17821 aaatttaggt ataaaagtaa agttaaattg cgttgctata agtgggttta atgatgatga
    17881 gcttaaagat tttatgtttt taacagttaa atcaccaatt gatgtaagat ttatagagct
    17941 tatgccatta ggtgaggcta atagagttta taagaagggt tattttaatg taaaagaaat
    18001 gattgaaaaa atatatggtt tatataaagt caaaaatgat gaaaaaagta cagcagaata
    18061 ttatatgttt aaaggagcta aaggaagaat aggaattata actccattaa gctgttcatt
    18121 ttgtaacact tgtaatcgta ttagacttac ttctagtggt gcaataaaat tatgtctaca
    18181 ttcaaaagaa gaaatagata taaaaccatt tttacataaa ccattgttat ttagagaatc
    18241 tatgaaagat ataataaaac aaaaaccaga aaaacatcat ttaatagaaa ataaatgtag
    18301 tgatacaaat aggcgtatgt atgaaattgg aggataagta atgttaacac atataaatga
    18361 aaaagggtat gccaagatgg tggacataag tgaaaaagat gatactaaaa gaacggctgt
    18421 agctacagct acaattactc ttagtaagga agcattagaa aaagtaaaaa atggtcagat
    18481 aaaaaaagga gacgtattgt ctgtagctca agttgcaggt ataatgggag ctaaaaatac
    18541 atcttcaaac ataccaatgt gccatcagat taaattagtt ggatgtgatt tagaatttga
    18601 tgtagatgat tctatgtctg ctattaagat atacgcaacc tgtaaatctc ttgggaaaac
    18661 tggagtagaa atggaagctt taaatgcatg ttctttagca gcacttacaa tttatgatat
    18721 gtgtaaagca gttgataaaa aaatggttat aagtaatatc catcttgtag agaagactgg
    18781 tggaaaatca ggagatttta agttcgagta aattaataat atattgggtt aaaatttgga
    18841 ggaaatatgg cgaaggtagt gtcaataaat ataagtgaga aaaaaggtgt aattaaagtt
    18901 cctgtacaat gtgcagagct aaaaataaat catgggatag ttggagatgc acatgcagga
    18961 aactggcatc gtcagataag cttacttgga aaagaaagca tagataaaat gaaaatgaaa
    19021 ggctttgacc aattaaaata tggagatttt gctgaaaatg taactacaga agggatagaa
    19081 gttttttccc tgcctgttgg tacaaagtta agaatagggc aatgtgaagt tgaagtaact
    19141 caaataggga aaaaatgtca caatggatgt gaaattaaga aattgacagg tgactgtgtg
    19201 atgccacgag aaggaatttt tgtaaaggtt ctaaaagaag gaattataaa tgtgaatgat
    19261 tcaatagatg taatctaatg aagtcactat taaaatataa ttataagtaa atactat
//
LOCUS       DAEPUT010000077        18699 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.079, whole genome shotgun sequence.
ACCESSION   DAEPUT010000077 DAEPUT010000000
VERSION     DAEPUT010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18699
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.079"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            210..1427
                     /locus_tag="KRL22_002936"
     CDS             210..1427
                     /locus_tag="KRL22_002936"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HBH1273387.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1522..1902
                     /locus_tag="KRL22_002937"
     CDS             1522..1902
                     /locus_tag="KRL22_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH1273388.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2186..2668
                     /locus_tag="KRL22_002938"
     CDS             2186..2668
                     /locus_tag="KRL22_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1273389.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSDVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2689..3504
                     /locus_tag="KRL22_002939"
     CDS             2689..3504
                     /locus_tag="KRL22_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1273390.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3557..5107
                     /locus_tag="KRL22_002940"
     CDS             3557..5107
                     /locus_tag="KRL22_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1273391.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEDY"
     gene            5204..6556
                     /locus_tag="KRL22_002941"
     CDS             5204..6556
                     /locus_tag="KRL22_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH1273392.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIVRGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6687..7445
                     /locus_tag="KRL22_002942"
     CDS             6687..7445
                     /locus_tag="KRL22_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273393.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITFKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7492..8211
                     /locus_tag="KRL22_002943"
     CDS             7492..8211
                     /locus_tag="KRL22_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH1273394.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHDGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8335..9735)
                     /locus_tag="KRL22_002944"
     CDS             complement(8335..9735)
                     /locus_tag="KRL22_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBH1273395.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9739..10647)
                     /locus_tag="KRL22_002945"
     CDS             complement(9739..10647)
                     /locus_tag="KRL22_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1273396.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10908..11555
                     /locus_tag="KRL22_002946"
     CDS             10908..11555
                     /locus_tag="KRL22_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1273397.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11880..14519
                     /locus_tag="KRL22_002947"
     CDS             11880..14519
                     /locus_tag="KRL22_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH1273398.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14577..15680)
                     /locus_tag="KRL22_002948"
     CDS             complement(14577..15680)
                     /locus_tag="KRL22_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HBH1273399.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16040..16861
                     /locus_tag="KRL22_002949"
     CDS             16040..16861
                     /locus_tag="KRL22_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1273400.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16940..17151
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17238..18554
                     /gene="argH"
                     /locus_tag="KRL22_002950"
     CDS             17238..18554
                     /gene="argH"
                     /locus_tag="KRL22_002950"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBH1273401.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
BASE COUNT         7147 a         2149 c         3311 g         6092 t
ORIGIN      
        1 aatgtaaaaa atatttttaa attatcattt aatgtaattt aaatgaattg aaaatatatg
       61 tttattgtat gcaattgttg tatttttagg ttttttgtga ttaattaaaa aattataaaa
      121 atcgtttaca tgttgatttt taaaaaaaaa agatatagaa ttatatagaa agtaataaac
      181 aaaaattgga tttacgggag tggaatgaaa tgatgaatgt taccttaaca gatgtgaaag
      241 aggctagaga gaccattaag aacatagtaa aaagaactga cttacttgaa agtgttaaac
      301 ttagcgaaaa aacaggagca aatgtgttct ataaatgtga gaatcttcaa aaaacaggtt
      361 cttttaaatt aagaggagct tgtaacaaaa tagcgagttt aacagatgaa gaaaaggcaa
      421 atggagttat agcttcaagt gcagggaatc atgctcaagg agttgcattg ggagcaaaaa
      481 tgactggtat aaaatctaca atagtaatgc cagcaactgc gcctttagca aaagttagtg
      541 caactaaagg ttatggagca gaagtagttt taaatggtgc ggtttatgat gatgcatatg
      601 caaaagctgt tgaaatacaa aaagaaacag gagcaacttt cttacatcca ttcaatgata
      661 agtatgttat agcaggacaa ggaactatat ctcttgaaat tttcgaacaa ttagacaata
      721 aagttgatac tatactatgc ccagttggtg gaggaggaat catctctggt gttgctgttg
      781 cagcaaaagc attaaatcct aatgtaaaaa tagtcggtgt tcaaactgca aatatacctt
      841 caatgaaaga gtcaataaaa aatggaaaag taacaacagc atttaatgat actacaatag
      901 ctgatggtat agctgttaaa actccaggag atttaacttt tgaaataata aatgaattgg
      961 ttgatgaaat agtagtggtt gaagagacag aaattgcaga atcaatatta tttatgatgg
     1021 aaagtcaaaa aatagtttca gaaggtgctg gtgctgtatg tacagctgct atattaagtg
     1081 gtaagtatgt accagcaaaa gatgaaaatg tagtttgtat aatatctggt ggtaatatag
     1141 acataaatac gttatataga ataataggtg ttgctttagc taaagaagga agaagatatt
     1201 catttagtac aattatggaa gataagccag gaaactttgc tgagttaact agaataataa
     1261 gtgagaatgg tggaaacatt ttaagtgcta atcaaggtaa attatcagca ggggaagctc
     1321 taggaaaaca aagtgcggaa tttatattag agacaataga ttatgaccat atagctagaa
     1381 taaagaaagc tatagaagaa aaaggtttta aaattataga attataataa aaagtgtata
     1441 taatatacaa gaaaaatagt ataatagtgt atgaagatac attttatgtg tattagatta
     1501 acgaattagg aggattttaa aatgaaacat gaagtaatac atactaatga tgcaccagca
     1561 gctttaggac catattctca agctataaaa gctggaaact tgttatttgt atctggacaa
     1621 gttcctcttg taccagagac tatggaagta gttgaaggag atgtacaagc tcaaactgct
     1681 caatctttaa aaaatcttaa agctatatta gctgaaagtg gagctgattt ttcaaatgta
     1741 gttaagacta cagtatttat aaaagatatg aatgaatttg gggctataaa cgaagtttat
     1801 gctgaatatt ttggagaaaa taaaccagca agagcttgtg tagaagttgc tagattacca
     1861 aaagacgtta aagttgaaat agaagtaata gctgtattat aaaaatacaa tatttttaat
     1921 ttgaaaaggc tgaaaaacta tattctagtg attcagcctt tttataaaaa aataaatcac
     1981 aataaagaac atgataaata ttgtcgaatt aaaaaataaa attaaaataa atattgcaat
     2041 atttttgaga aggttttata atgagtatat aatttgaaac gtgtaactat taaattaggc
     2101 atgagttctt ggatattttt atcctgagga ttcatgcctt ttttgtattg aaattcaaaa
     2161 atctatttaa taaggaggaa gtactgtgtt aaattttttc aagaaaaata aaagctataa
     2221 gttacatgca gtagtgagtg gtaacagcat taatattgag aaagtaaacg attctgtgtt
     2281 ttcaaaaaag ttaatgggag atggagttgc aattattcct aatagtgatg ttgttgtagc
     2341 cccttgtaat ggtaaagtaa ctgtgcttac agaatcaaag catgcctttg gtatggtctc
     2401 agatgagggt gttgaaatat tagtccacat aggaattgat acagttagtt tacagggtga
     2461 ggggtttaaa aatgaagtgt ctcaaggaga tactgttaaa aaaggtagtc caataataag
     2521 ttttgaaaga gaaaaaataa attctcaggg aattgattgt acaacaataa taattgtatt
     2581 aaatcatagc gaattttcag aaataaattg catggtagaa aatgaagttg ttgcagggca
     2641 agatactgtt attgaaatta tgaaataata ggaagggatt aattcaatat gagagtagta
     2701 aaaatcttta ataataatgc attatctaca gtaactaatg ataggaaaga agctatttta
     2761 ctaggtcttg gtataggttt taataaacgt ccaggagata aagttaatga agataaaata
     2821 gaaaagattt attatgttca agaccacatg caaacaaaat ttttagaatt attaaaaaat
     2881 gttagtccag aagtgatgga tgcttcacaa caaattataa gtcttatacc aggaaatgag
     2941 ggaaaattta ataataaagg gatattatct ttagtggaac atattagttt tgcaatagat
     3001 agaatgaaaa ataatgtttt tttacctaat ttaatgcttt tggatataaa gatgatgtat
     3061 tcaaaagagt ttgaattagg agtaaaagct ttagaaatta tatatagagt atgtcatatc
     3121 catttgcctg aagatgaagc aggttacata gctttacatt ttgtcaattt acaatcaaat
     3181 gataatttgg catatgatac tttaaaattt gtaaaaggta gtattgattt gattaaagaa
     3241 tgttatggat tagaattaga cgaatcgagt ttaagtacat tacgttttag aactcatctt
     3301 aaatttcttg ctcaaagaat ttttaagaat gaaatttgtc aggatgataa aatgattgaa
     3361 atgtatgatt atttaattaa caatcatcct aaaaataaag aatatttaga aaagttaaat
     3421 gtatatattg aaaaggagtt taggtataaa ttagataaac ctgaaaaaat ttatctacta
     3481 ctacacctaa caaaaatctt ataagaatga gatgaattag taatagaaat atatataatt
     3541 ttaggggggg ataagattga aagaaaaact acttggagga ctggaaacat ttgcaaaggc
     3601 aatggttcag ccattaatgt atttatcgag tgcaggaata ttaatggtgg taggtgtact
     3661 acttacaaat gatatgttat taggagtact tccatttttt aaatgggagc caattcaaat
     3721 atttggaagc ctaatttata actgtataat ggctattatt aataatcttg ctgttatatt
     3781 tgctataggt attcctgctg cactagcaaa aaaagagaag cacaaagcag cgttaatagg
     3841 atttatgagt tatataatat accttacagc ttccaacact atgttaacat cactaggtca
     3901 actagcaaaa gaaagcaaga tgcttggact gatagggact ggacaagcta ctattttagg
     3961 tattcaagtt gtagatacaa gtgtatttgg tggaattatt ttagggtgta tagctggata
     4021 tgtatttaat cgtacaagca acaaaacatt taaaggagct ttacagatat actcgggagc
     4081 aaattttagt tttatatgca tgttctttgt atccatttta attggagttg tgagtaactt
     4141 tatatggcca ttagctcaac aaggaatagc ttctcttgca aatgtcatca aagatacagg
     4201 tacatttggt ttattcttat atggtttttt agagagaata ttagtaccaa ctggacttca
     4261 tcatttaatt tatacaccat ttcagttttc tgatttagga ggagtgctta aagttggtgc
     4321 agatacagtt tcaggagcct atgctatagt tatgacagaa atgaatttac cagttgagcg
     4381 tttctcagat agtatatact acatggcaac tggatttaca aagatgtttg gttatatagg
     4441 tataggagct gcctttattt atactgcata taagcaaaat aagaagaagg ttaaggcaac
     4501 gattattcca ctaataatta cggcagtatt agcctctgta acagaaccat tagactttat
     4561 gtttgtattc tgtgcaccac ttttattctt tgtacatgca gttatagctg gtctttttat
     4621 agctttatta aaaatatttg atgttactgc attatgtgga gggaacttat tagtatcaat
     4681 tataatgaat actacagtag gcgtagaaaa aacacactgg ccagtaatga tgatattagg
     4741 acttgcacaa attattgtat attttgtagt atttagtttt ttaattaaga aatttaatta
     4801 taaaactcca ggtcgtgaag atgagagtac agctacaggc gaagaacaat caaaacaact
     4861 taatttagat gcaggtatag aaaatataat tgatgggtta ggcggaaaag aaaatattaa
     4921 tacagtagaa aattgcatca ctagattacg tgttaatgta aaagatgaaa gtaagattaa
     4981 tgaagatata attaatttaa cgccaaatag cgggattgta aggaaaggaa aagatataca
     5041 aataattttt ggacttcatg tgcatgaggt aagacgtgca gtagaagatt ttttagaaga
     5101 ttattaaaga tatatattta tatagcaagg gtaaataaca gctttaagtg ctgtttacta
     5161 tttattaaag atacatataa tttatagagg aggaataatt attatgatta ttactattgt
     5221 tggtggagga agcacattta ctccaggtat tgttaagtca attgcgttaa gagaaaaaga
     5281 gttagagctt gaggaaattc gtttatttga cattgataaa gaacgtcaag ataaagtagc
     5341 tgtagttgtc aactggatac taaaagaaga tgttaaaaca gatgttaaac taactgtaac
     5401 taattgtgaa aaagaagcgt atacagatgc tacatttata tttgcacaaa tgcgtgttgg
     5461 taaatatgaa atgcgtgagc aggatgaaaa aattccattg aaatatggtt gtgtaggtca
     5521 agaaacttgt ggttgtggag ggatggcata cggactgcgt acaatacaac caatgataaa
     5581 ggttattgat gatgtagaga aatatgctaa aaaagattat tggatattaa attactctaa
     5641 tcctgctgca atcgtttctg aagcttgtcg taagttaaga ccaaatgcaa ggattataaa
     5701 tatctgtgat atgccaatag ctattataga tatgatagcg gggtcattaa atatcaatga
     5761 cgttcataat atacgctatg attattttgg tctaaatcat tttggctggt ttacttcaat
     5821 agattataaa catagagact taatggaaga gattaaggaa tacataaaag aaaataaaat
     5881 attattacca aaatcttata tagaaaactt aaataaaagt cgtagtacag gaaatcgcca
     5941 tgctgtaagt agctggatac atgtttggga atctgtttat acaatgttag aaagcttccc
     6001 aaaatatctg ccaaacactt atttaacata ctatctttta agtaaagaaa cagtggaaca
     6061 ttcaaacata aatcgtactc gtgcaaatga ggttatggaa agccgtgaaa aagacttatt
     6121 tgaaggtgtg agacattact tagaaactgg agaaatttct gaaaaagcat tttatgcagg
     6181 ttcacatgga gattggatta gtgatttggc agtttcaatt aaaaatgata cacgtagtcg
     6241 ttttttagtt ataactgaaa atcgtggagc tataccaaac atgccatatg atgcaatggt
     6301 agaaattcca gcatatattg gtaaagatgg tccagaagtt attgttcgag gtccaatacc
     6361 tctattccaa caaggattaa tgatgcaaca acttaacagt gaaaaattga tagtagaagc
     6421 ttatatagaa aatagttatg aaaaagcttt acaagcattc acattaaata aaactattcc
     6481 aagtatgaat gttgctaaag aaattttgga tgaaatgata gaagttaata aggaatactg
     6541 gccagaatta agatagtagg ataaaagaaa gggtttttat ttaataatta gatatgtttt
     6601 cagagtcttt tatcaaaatg tattcacaaa catatggcaa tatattaaaa taaagagtga
     6661 tatttttaga agaatggggt gatgcaatga acattataaa taaaattttt tggcaagaag
     6721 ataggattgg catgattaca aataatttag aggcagatac acatagccac tgtatgttac
     6781 aactgttctt agggatagaa gacagcattg aaataacagt caatgaaaaa ttagttaaat
     6841 gtaattgtat catagtagat aaaaatatct ctcattcatt ttcagcaaga aaaaaagttt
     6901 attactctgc tattattgaa cctacatcta tatatgcaga acagcttacc tcaaaaatga
     6961 atgattttgg ctactggata tgtgacaatg atggattaga gaaattacgt caacaaggaa
     7021 cttttttgat agataactct agtaaagaac aatatttaag atttatggaa atgcttaata
     7081 actatttgaa tatacctata actttcaaac attatgatga cagaattact gaattgctca
     7141 atttattacg tacttgtaat tgtgataatc atactatttc aagttttgca gataaagtgt
     7201 ctctatcagc aagtagatta tcacatctgt ttaaagaaca aatagggata cctttaaaaa
     7261 gctatatctt atttcatcaa atggagtgtg cttttagaga attactttct ggaaaaaatg
     7321 ttaccgaagc ttctatgact gctggattcg atactccatc acactttgca gggacagtta
     7381 agcgaatgat gggaatgcct gtttctttat ctttgaaaga tagcgagttt ttgaaagtat
     7441 attaaatatt ctcgttatat aatgaagttg tactaagaaa ggggctttgt tatgaataaa
     7501 gaatatttag aagaaacaaa aatgttaaat tataatgaac cacaacttaa gcttttggta
     7561 tcatcaaaga attggttgga attagatgat tttcataaaa taaaatctat ttatgagttt
     7621 gtacagaatg atattttatt tggatataat gcttctgata tgttaagcgc aacacaggta
     7681 ttaaatgatg gtatgggaca atgcaataca aaagctactc ttttaatggc attattacgt
     7741 gcagtgaata tcccttgtag gcttcatgct tttgatgtaa caaaagattt tcaacgagga
     7801 gctacatcca aattgatttc actattagca ccaaaatata ttcttcatac ttgggtagag
     7861 gtattttatc aagataggtg gattgctctg gagggtgtca taactgataa aaaatattta
     7921 gaagcaattc agaagaaatt ttttaatcat gatggaacgt ttaaaaagta tgcaatagct
     7981 acaaatgatt tgaaaaatac atctattgat tgggatggta aagatacttt tatccaaaaa
     8041 gaagctatcg tgtatgatta tggtattttt ccatcaccag acgtattttt ttctactcat
     8101 tcacaacata tgtcaaaatt aaaaaatttc atatatgtac atcttatcag aaaaataatg
     8161 acaaaaaatg tatgtaaggc tagaaataat tatattgata aaaatgaatg agtgtttaag
     8221 aggtaactat ataggaaata tatagaataa ttaaaactgt actggttaaa atgaataaaa
     8281 aggagttatc acagagcaaa cttaaattgt tcataggata actccttttc tgtattaact
     8341 tctaataatt tgatgtcttt ttataaaaca tatagataca attaaaccag taaatgcaag
     8401 agtagctgct attgaaaatg caacatctat tccatgaatg ttagacagca tgtttgaact
     8461 catatgagct ttcttagtag cacttgtcat tatagtaata agtatagcag aacctatagc
     8521 tccagatatc tgacggagtg tgttattaat tgctgtggca tgagatataa gttctctatc
     8581 taatgtttta attccccatg tagttaatgg cattaaaacc attgaaatac caatcatacg
     8641 aatacaatac atcaatgaca catgaattaa agatgtatct ctgcctaaaa aagcgaagga
     8701 taaagttcct aaaaacaaac atcctgttcc taatattgat agagcatgag gtccatattt
     8761 atctaaatga cgtcctgcaa ttggattgag tacaaccatc aatatagcac caggtaacat
     8821 taatgaacct gaagataatg cagaaaatcc tcttacagat tgaacgtaca gaggaatcat
     8881 taatgtagca gacatcattg aggcatatac aatcataatt aatattgtag aaataagaaa
     8941 tggtttattt ttaaaaaccc tcaattctaa aaaaggttct ttagatttta attgacgcaa
     9001 tgtaaataaa attaatgaca taattcctat taatattggt aaatatgtgg caatattagt
     9061 ccacccataa ttaccttgat tagtaaatcc aattaataaa ccaccaaaac ctagagatga
     9121 tagtactatt gaaggtatat ctaattttag tttttgagtt tccccaacat ttcttaatag
     9181 aataaatgat agtataacat ctaatatagc aataggggaa agaaacagaa ataaactatg
     9241 ccaaccaaat gaatctacta accatcctga taaagttgga cctattgctg gagcaaatcc
     9301 tactgtaata ccaactaaac tcatagctgc accacgtttt tcctcagggc ataaatagag
     9361 tataataact tgtaaaagtg gcattagaga accagaaccc attgcctgca acacacgagc
     9421 aatcaacata gttgaaaaat tattagaaaa aagtgcaata atacatccta tagaaaagat
     9481 agacattgat gtaataaata actttctagt actaaatcga tttattaaat aagctgttgt
     9541 gggtacaata atacctgcaa taagtagata aattgttgtt aaccactgac caacatcagc
     9601 agtaatttta aaatctgaca ttatattagg taatgctgtt gacaatagtg tttgactgag
     9661 agaacttata aaagcgccag tcattacaat tgctattatt aaatttcctt ttttattgtt
     9721 actttgggtt tccataattt ataacgtctc cttttttaat tgatttttaa tgctgttcaa
     9781 taaaagtact tttggtctta aagtgtcttc tttttctaaa tatgcaatca ttgcatccat
     9841 aattaaagaa tcatattgtt gattttttcc ttcgacgtat aattttttta ttgcttctag
     9901 taatttagga ttttcaagga gagaagtatc agttttgatt agttcttcta tatcttgtat
     9961 cgttttaaaa aatagcgatt tattatgaag ggaaaagtaa acttcatctt cttgtttatg
    10021 taaaaacatt gatttttcaa ttaaaggatt tagattatcc atattttcta caactaaatc
    10081 tagaatttgt atagtaaatt tggcaataaa gtatacattt atttctcttt tttgtacatg
    10141 aataatgtat ataaactgat gaattagagc atccaataag aaaactaaat caaatataat
    10201 tttttctatt ttatcaccat agttatcaaa taagcttagt ttgtattcat tcaataagtt
    10261 agctcttgat tttgtttgca atttacttgt agccttacgt tgctcttcag aaaagttttc
    10321 tcttatatag gtatttatgg tagttctaga aaaaatattt ttccatacag caattatctt
    10381 tctgtttaac ttttctgatg atggaatgtc attattttca tttatggaat gtataatttc
    10441 taaaaacttt tcatcataat aattgattat ttcgcagata aaactttcct tagtttcaaa
    10501 atgcttgtaa aaagtagctt tagacatttt acactctttt acaacatccg atattgaagt
    10561 attttgaaaa cctttttggt caaaaatttt ttgtgcaata gttataatga gcctttgttt
    10621 ttctgtcact ttattatctc ctttcacgca aaaacgttta gtactatata gtacctacaa
    10681 gttttgataa atatattata catcatttgg aaaaaaaatc aatatataga ctgtaatatg
    10741 aaatttttga aaaatttgtt gttattttta gtcgtataaa aaagaaactt aagagtttct
    10801 taagaattgt ttaaagaagt tgcaataaat tagtggtatg attatagtat gaaagagaat
    10861 gtcttgaaat ttttctgtat caaattccaa ttatggaggt gtagtatatg aaaaagaaaa
    10921 tttgtgtagc aataattttt gctctattta tagtttttgt agaaatgttt attgatagct
    10981 ctagcgaagg aagtaaaatt atgacagctg aattaagtaa atacaggaaa ggcgtaaatg
    11041 tattatcaat aaacaatatt atagtagcga ataaaaaata tagtttgccc aaagattatt
    11101 ctcctcagga aagcagtgaa gcgagagatg ctttttataa aatgaataaa gatgctcaaa
    11161 agtcaggatt aaatttaaaa gcttttagta catatagaag ttatgaatat caagatagat
    11221 tatttaagtc atatgtaaaa gaacatggag aaaaagaagc aaatagattt tcagctaaac
    11281 ctggagagag tgagcatcaa actggacttg cttttgatat tggaggagat gaccagtctt
    11341 gttgggcaaa taaaaagttc aacaatacaa aagaagctaa gtggttgtat gaaaatgcat
    11401 ataaatatgg ttttatactt agatatccag aaggtaaaga gaatataaca ggatatatgt
    11461 atgaatcttg gcactataga tatgttggaa ctgaacatag caaaaacttt gcaatgaata
    11521 atttgacttt agaagaatat ttacatataa attaagagat ggtttgttaa aattaggtta
    11581 aaataaaaaa taacctagac tattagctgt gtaaagtgat ataatgtaaa tacaatttaa
    11641 gataactact cgaaggggag tagcttacac gaaagtggta attaatcgtc aagacagtag
    11701 aaatactcgg ttaattagca agggattcct tgatagcaag accttcaaaa taagcattag
    11761 gtatgtttgt tttggggtct ttttttattc aaggaatttt tatttaaaaa aatttaaatt
    11821 tcaagtatac ataagagccc ccaaacataa aataaattta ttgaagagga gggcaacaaa
    11881 tgtcttacaa aagtacttat caagaagtaa ttaaaaattt agactcaagt ttatctggtt
    11941 tgagtaaaga aagagcagaa gagttgttag aaaaaaatgg agctaatgaa ttaaaagaag
    12001 cagataaggt tcctacttat aagcttttcc tagaaagttt taaagaccca ttagtaataa
    12061 ttctattgat agctgcttta gtacaaatat ttttaggtga aacagtggag tctataataa
    12121 tttttgcagt tattattata aactctgttc tgggtgttgt acaaacaaaa aaagcagaaa
    12181 gttcattaga aagtttgaaa aatttatctg caccaaacgc aaaggtaata agagacaata
    12241 aaaaaatgac aattccagca aaaaatttag tagttggaga tattgtattc ttagaagctg
    12301 gcgattacat accagcagat ggaaggctta tagaagcaca atctctcaag gttgtagaag
    12361 ggatgttaac tggagaatca gaaccagttt taaagcatac agaaaaaata agtgaagatg
    12421 taagtttagg tgaccagaaa aatatggtat ttagtggtgc tgtagttgtt tatggtagag
    12481 gttcttttgt agtgactgga acaggtatgg atactgagat gggtaaaata gctgggcttt
    12541 tagaaagtgc tgaaaataaa cttacaccat tgcaacaaaa aatagaggat tttagtaaaa
    12601 aacttggtgt aggtattgta atacttgctc ttttaatatt tataattcaa gtagcaagaa
    12661 attactttat ggctggaaat ggagaaatga cacaaattat tttagattca ttcatgttct
    12721 ctgtagcagt agcagtagca gctataccag aagctctatc atcaatagtc actatagtat
    12781 tggctgttgg aacaaatagt atggcaaaaa aacaagccat aataagaaaa ttaccagcag
    12841 tagaaacttt aggttcaaca agtgtaatat gtactgataa aacaggtact cttacacaaa
    12901 ataaaatgac agtagttgat tattatatgt atggaactaa taatgatgag ttagataaag
    12961 aaaaagtaaa ctattcttat catgctaaat tattgactat ggtttctaca ttgtgtaatg
    13021 actctcatat aactagtgat ggtaaagaag ttggtgaccc aacagaagtg gctttaataa
    13081 attattcaag taaaaatgat ttagattatg ataaattaag aagtaagtat atcagaataa
    13141 atgaaatacc atttgactca gacagaaagc ttatgtctac tgtaaatagt atatatggag
    13201 attatataat gtttacaaaa ggtgctccag atattgtgtt tagtagatgt aaatatgctt
    13261 tgaaaaatgg ttcaaaagta gatataacag atgagataat agaagaatat aaacataaaa
    13321 atgaagagtt ctcaaataga gcacttagag tattagcttt tgcaataaaa gatgtcccag
    13381 aagaagattt tataccttca attgatgacg aacatgacat gacattggtt ggaataatgg
    13441 caatgataga cccaccaaga gaagaagtaa tggatgcagt aaaagaggca aagagtgctg
    13501 gtataaaaac tgttatgata actggtgacc ataaaacaac agcagcagca attgcaaaag
    13561 agattggtat aatggaagaa ggagacttgg ctcttactgg aaaagagctt gatgctttga
    13621 gtgaagaaca actatatgaa aaactagaaa atataagtgt atatgccaga gtctcgccag
    13681 aaaataaaat tcgtatagta aaagcatggc aacataagaa taatataaca gcaatgactg
    13741 gtgatggtgt taatgatgca cctgcattaa aacaagcaga tataggaatc ggtatgggaa
    13801 gtggtactga tgtagcaaaa gatgcttctg ctatggtatt ggttgatgat aactttgcaa
    13861 gtatagtaaa tgctgttgaa gttggtagaa cagtatacag taatataata aaatcaatta
    13921 cttatctatt tgcaggaaac ttaggagcta tagtatccat agtatttgca gtgtttgcag
    13981 gttggtcaaa tccatttaca gctttacaac ttttgtttat aaacttagta aatgactctt
    14041 taccagcaat tgcattaggg tttgaaaagt cagaaaaaaa tataatgaat aaacctccta
    14101 gacacccgga tgaaagtata ctagcaggag gaacattgaa ggcagttgct ataagaggtt
    14161 gtataatagg tgtagttaca ataattgcac aatatatagg attacaagta tctccagaac
    14221 ttggagtagc aatggcattt tcaacattga tattagctag aataatgcaa acattacctg
    14281 cacgttctaa taatcaaaca gtaataaaat taggtttttt cagcaataaa tacgttatag
    14341 gagcagtttt agtctgtctt gggctttact ctttaacact aataccagtg ctaagaggaa
    14401 tattctctat accaacaacg tttggattgt accagttggg gatttgccta gggttagcat
    14461 taatttcatc aatattaatg gaacttaaca aattaataaa tagaagtgaa gtaaaataat
    14521 caaaaaatta aagggcatat tgattttaac aatatgcctt ttataaatag tctaatttat
    14581 tctatattat cgattatttg gaatgctttt ataacttcag gtaattcttt ttcttcaggc
    14641 attctaaatc ttatgaaatt tttatcaagt ccagtaaaat cacttccaga tataactctt
    14701 atttttaatt tagcaaactc ttgttgtaaa tctatgtcct tgtttttatg ttcaactgtc
    14761 ataattgata cagtatcact agtttcagct atattaaggt ttttccatgg aattaataat
    14821 tgatttttta tatcttttgt tttttctttt aattcttcta taaattgaac atcatctaat
    14881 aaatttgctg caatactacg agatatttca gacacttcgt aaggagtaga aatcttttta
    14941 atagggctaa caagttgttc tggaagaact gcatatcctg ctcttagtcc tgctaaacca
    15001 aatccttttg aaaatgtttt taaagcaatt acattatcat aattatttag aagcttgaca
    15061 gctgaatttt cttttggcat gtattcacca taagcttcat ctaccataac tgctatatca
    15121 tatttagctg cttcctttac tatattttca attgatgata aaggtataat ttgtcctgta
    15181 ggattgtttg gattgtctat gtaaattact ttatattctg gatttatttt ttcaataaat
    15241 tctttttcat taaacttgaa attatcctct ttctttaaaa gaacataatc ataagttgca
    15301 ccatgcattt ttatatctgt ctcatattct gagaactgag gtgaatatcc taaaacttta
    15361 tctccctttt caataaatag tctatttaaa aggtaaataa catgtataga accatctgcc
    15421 aaacaaattc tgtcagtatc taatgctata aaatctttcc aataatcgac tatattatct
    15481 tttaaagcaa ttgaatgagg atatcctctt atcatatcaa attttaaagc attaaaagct
    15541 tctacagctt tgtttgagta agacacggta tttatacctt caccacagtc tatctcgaat
    15601 acatcttctg aatgtccaga ttctattgca taactttttt tcaactgcat ttcaatagct
    15661 ttgttaattt ttagtttcat actttatcac tccttattta gtcaataata aatgttataa
    15721 aagttgctag atttaaaata ttatgaaaat atataatagt aaaaatgaat ataaatatta
    15781 taatagctca ctttatttaa tatgattata tatcatatat tgtaaaattt ctagcattat
    15841 aagactataa attgaaaata ttcagaaaaa tactacaaga aacgatttat tttgctctta
    15901 aaataagtta aatgaatgtt attaattttg taaattgaaa tagtttaagt ataaagttat
    15961 gatataatct aataagggta attctttaga ttatattaag gaaatatagg tatacaataa
    16021 aaagttatgg agttggatta tgggatataa attaattgta acagatatgg atggaacttt
    16081 attaggcaat aatcataaag ttacagatga aaataaaact gcactacaaa aagttataaa
    16141 aagcggtatt aatgtaactt tagcaacagg aagagccttc gattcagcta aatgcaatgt
    16201 agattttctt aaagaggaca tgccaataat agcttgtaat ggttcattaa taagagagca
    16261 aaatggaaat ataatatatt caaataagat tgatacaaga acatgtttaa acattttaga
    16321 tgtattagat aaatacgata tttactacca atgtaatagt atagattcta tgctttcgaa
    16381 aaaaatagaa ggacgtgaag atagattaag tgtattttta ggctctgaaa cagaagtaat
    16441 tgtaaaagat gatttgagag aagaaatctt taaaaaagat atactaaaat ttgtaatcat
    16501 agaagaaaaa aatccatcta ttttggatga aataagaaaa gaattgagaa aagttcaagg
    16561 aataaagata acttcttcat ggccaaacaa tattgaagtc atgaatgaag gtgttgataa
    16621 aggtaatgca gttaaaattt tagctgaaaa aatgaatata gacagagaag atataattgc
    16681 atttggagac aattacaatg acatagaaat gataaagttt gctggtcttg gggtagctat
    16741 gggaaatgca gaagaattga ttaaacaaga agctgattat gttacagata caaatcaaga
    16801 cagtggagtt gcaaaggcaa tttataaatt cctagagtta aaagaatcac ttagctctta
    16861 aaacagtata taataggaaa aaataggttg actattttgt agatagtaat tataatacaa
    16921 atagataaaa cataaaaatt tagattcagt gaaaaagaga gtagatatag agaaaatctc
    16981 agcgaattgg gggatggtgt gagcctaatg ataacacttt atattgaaaa gaactttgga
    17041 gaatactact tgaaattcag tatggtagta ggtaatctcg ccttaagaga atagagtggg
    17101 taaacattgt ttaccaacta gagtggtaac acggaatatt tcgtctcttg gtctttttga
    17161 ccaagagatt ttttagtttc attgagttac aagacttata attaaaatac aaaaaattaa
    17221 aatatgaggt gaaagttatg aaattatggg gcggacgctt tagaaaagcg gaaaatcaac
    17281 ttatggaaga atttaataaa tcttttggct atgattgtgt actgtacaaa aaagatatcg
    17341 aaggaagtgt agcacatgtt catatgcaag taaaatgtgg acttttaaca gaagaagaag
    17401 gaaagtctat aacagaaggt ttaaaaggga tacttgaaga tgtagaaaat ggaaagttag
    17461 tattggatgg agagtatgaa gatatacata gttttactga gataaattta attcaaagaa
    17521 ttggagatgt tggcaagaag cttcatacag cacgtagtag aaatgaccaa gttgcagttg
    17581 atatgagatt gtatgctaaa gaaaaagcaa atgatttggt ggatttaata tctgaattta
    17641 aagctactat aaaagatgtt gctgacaaaa acccagtgat gatgccaggc tatactcatc
    17701 ttcaaagggc acaagtagtg acatttaagc atcacttaat ggcatattat agtatgtttg
    17761 atagagatga gaaaagaata aaaaatgcta tagaaatatt agatgaatca cctttaggct
    17821 gtggagcttt agcaggaact acgcatgata tagatagaag tataacttgt gaacaattag
    17881 gatttaaaaa agtagtagat aattttatgg atggagtaag tgatagagat tatttactag
    17941 agctaatgag tgatttttca attataatga tgcacttaag tagattaagt gaagagttga
    18001 tactttggag ttctcaagaa tttggatttg ttgagataga tgatttatat acaactggaa
    18061 gtagtataat gcctcagaag aaaaatccag atggtgcaga gcttataaga ggtaagactg
    18121 gtagagtata tggaaactta tttggtcttt ttacagtaat gaaaggaata ccattagcat
    18181 ataataaaga catgcaagaa gataaagaag gttttttcga tagtgtacat actcttgaaa
    18241 tgtgtataca aataatggat agaatgatag ccacactaaa ggtaaatgag gataaaatga
    18301 aacaagcagt aaaaaatggt tttttaaatg caacagaagt tgcggattat ttggttaaaa
    18361 ataatgttgc ttttagagat gcacatggta tagtaggaag tatcgttata tattgtgaag
    18421 ataataaaaa agcaatagaa gatttaacat tagaagaatt acataagttt tcagatgctt
    18481 ttaaggaaga tatttatgat tttatcgact atgagagtat attaaataag ggaataaaaa
    18541 agaatttaaa ataatgtatt tatttttaaa agctgtaaat ttgaatgtta tcatttaaat
    18601 ttacagcttt ttattgtgta agattttatt atataaaagt aagaaactta aaaggagtag
    18661 tatttaaaat aaatacaaat aaaaaattat tattaaaat
//
LOCUS       DAEPUT010000078        18660 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.080, whole genome shotgun sequence.
ACCESSION   DAEPUT010000078 DAEPUT010000000
VERSION     DAEPUT010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18660
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.080"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(12..890)
                     /gene="speB"
                     /locus_tag="KRL22_002951"
     CDS             complement(12..890)
                     /gene="speB"
                     /locus_tag="KRL22_002951"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBH1273402.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNILNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISNKIK"
     gene            complement(880..1731)
                     /gene="speE"
                     /locus_tag="KRL22_002952"
     CDS             complement(880..1731)
                     /gene="speE"
                     /locus_tag="KRL22_002952"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBH1273403.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            complement(1761..2174)
                     /gene="speD"
                     /locus_tag="KRL22_002953"
     CDS             complement(1761..2174)
                     /gene="speD"
                     /locus_tag="KRL22_002953"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBH1273404.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            complement(2261..3736)
                     /locus_tag="KRL22_002954"
     CDS             complement(2261..3736)
                     /locus_tag="KRL22_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH1273405.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            complement(4374..5027)
                     /locus_tag="KRL22_002955"
     CDS             complement(4374..5027)
                     /locus_tag="KRL22_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1273406.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERVLREHWKTIPIAEMKKEKLL"
     gene            complement(5272..7137)
                     /locus_tag="KRL22_002956"
     CDS             complement(5272..7137)
                     /locus_tag="KRL22_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HBH1273407.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKNSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKTADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(7142..9562)
                     /locus_tag="KRL22_002957"
     CDS             complement(7142..9562)
                     /locus_tag="KRL22_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HBH1273408.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(9576..11018)
                     /gene="glgA"
                     /locus_tag="KRL22_002958"
     CDS             complement(9576..11018)
                     /gene="glgA"
                     /locus_tag="KRL22_002958"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBH1273409.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRFDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(11047..12177)
                     /gene="glgD"
                     /locus_tag="KRL22_002959"
     CDS             complement(11047..12177)
                     /gene="glgD"
                     /locus_tag="KRL22_002959"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HBH1273410.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(12179..13339)
                     /locus_tag="KRL22_002960"
     CDS             complement(12179..13339)
                     /locus_tag="KRL22_002960"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBH1273411.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            complement(14110..15153)
                     /locus_tag="KRL22_002961"
     CDS             complement(14110..15153)
                     /locus_tag="KRL22_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBH1273412.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(15174..15620)
                     /locus_tag="KRL22_002962"
     CDS             complement(15174..15620)
                     /locus_tag="KRL22_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBH1273413.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISSNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            complement(15794..17374)
                     /locus_tag="KRL22_002963"
     CDS             complement(15794..17374)
                     /locus_tag="KRL22_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HBH1273414.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIGMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            18173..>18660
                     /locus_tag="KRL22_002964"
     CDS             18173..>18660
                     /locus_tag="KRL22_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273415.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKS"
BASE COUNT         5923 a         3295 c         1868 g         7574 t
ORIGIN      
        1 tataaaatac tctatttaat tttattagat attattaagc atagctctct taagatttta
       61 caagctataa ctgtcgatac acctgttgta tcgtaatcag ggcttaactc tacaatatca
      121 caaccaacta tatttatatt agagtttttt ataatcttaa aaatctcttg aaactctcta
      181 taatttacac caccaggttc tggtgtacct gttcctggaa acacagatgc atccaataca
      241 tctaaatcta tagttagata aatattcttt ccatttagta tattaactat attttcaaac
      301 gtatctattc ctcctatttc catgtatgtg tgtttttctt ctgtagcaaa tttaaattct
      361 tcttttgtcc cagaccttat accaaattga aatattttat tatcacctac aatatcccat
      421 attcttttaa ttactgttgc atgagaattt ttactattat tatattcttc cctcaagtca
      481 gtatgggcat caaaatgaat tacatatata tcattgtact tttcatgtac tgctttaaag
      541 gctggtaatg taactaaatg ctctcctcca atcataaagg gtacctttga atctctaaca
      601 atcttatatg tctcttgata aatttctttt aagacttgtt ctgtacttcc aacactaatt
      661 tctaaatctc cataatcaca tatattataa tcctctaaat ccaaatctaa aaaaggacta
      721 tatgtctcaa gaccgtaaaa ttcttttctc atagagctac ttgcaaatct agccccaggt
      781 ctgttagaag tagttccatc aaatccaaca ccaaatacta taagattaga ttcttcataa
      841 tttttgtcca tactcataaa agtgttcata tgatagaaat tattcttcat ctagcatctc
      901 cttcacgtat tgaggtaaca taaacgaacc taaatgtata tcactattat aatatttagt
      961 ttttaaactt aatttctccc atccatttct atcttgattt tttactggat taagtttttt
     1021 tgaagcaaat ccaaacaacc agtgaccaga tggatatgtt ggtatatgtg cttgataaac
     1081 ttctgatatt ggaaatatct gttttaattt tttattagct cttttcatct ctttagcatt
     1141 aaagtcaaaa tacggacttt cactttgatt tactaaaatt ccatcatcag tcagtattct
     1201 ataacaatcc ttataaaaat cagttgagaa aagcccttca cctggtccta ttgggtcagt
     1261 tgaatctact attatcaggt catatgattt atcatgtgca cacttaacaa aattaacacc
     1321 atcttcaaaa tataaactca ctcttttatc atctaattta catgagcata tatccatata
     1381 ctccttagat acatctacaa ccattttatc tatttcaacc atgtcaatct tttctatttg
     1441 aggataacgg cttaattctc ttactgtacc tccatcacct ccacctatga ctaatacttt
     1501 ctttatgttt aaatttgtag ccataggaac atgagttatc atctcatggt atataaattc
     1561 atctttatat gttaccatca ttaatccatc tattgttaga aattttccaa attcatcact
     1621 atcaaacaca tctatccttt gaaattgaga ctttccttca aatagatgtt tatttacttt
     1681 tatagaaaat cttacatttt ctgtccattc ttctgtatac caaagttcca tataataatc
     1741 ctcactttct cttgtatgtt ttatactgct tctggtttat gagtaatctt acctaaatct
     1801 ttttttgaat attttttaat ttttgtagtt aagcctcttg gaatttctgt agactcgctt
     1861 ctttcagact ttaaaagttg ctctaataat tcaaaacttt tccatgggtc tatatcacca
     1921 caagtaaaaa aatctgctgc tgcatagcca tattcaggcc atgtatgtat tgtcaaatga
     1981 gattcagcaa ttataacagc tcctgaaacc ccccaaggat taaaatggtg gaatacagaa
     2041 tccacaattg tcgcttttgc atttaatgct gaatcattca taaaattttc tataagacgt
     2101 gggtctttaa gtacgttttc atcacaatta tagtattcta ctagtatatg tcttcctagt
     2161 gtttcaaatt tcatttcaac cccaactcct ttatactttt aataagttct atttgataaa
     2221 ctctacttaa caaatacttg cccttgcaaa ataaagtaat ttattttatt actagtattc
     2281 tatctaagtt tttatcttgt acatctgtaa gatacgcatt gctatttttt aagaaaataa
     2341 tatactccat aatttcttct gttatcaatt ctcctggagc aataatcggt atacctggtg
     2401 gatatgccat tattgattct ccacaaattc tatctataca tgaattgatt tctacacttt
     2461 cctttggtgc ataaaaagct tctcttggat taagtttaat aattggattt atttgaacca
     2521 tattaaattc atttaatgtt gattcttttc tataaatctt tgcaattata gaaagtgcct
     2581 ttactaatct atctatatct gatttatttg ttccaatgga cacaagtgcc agtatattat
     2641 atgaatctcc caattctact tgaattgaaa aatttttata taataaatcg tatacttcaa
     2701 atccagtcaa atttaattct tttacattta tacacaattt tgtttcatct ataaatttaa
     2761 cacctttttg tttcaatatt tctgtagata aaacttttat tccatcaatt ttgtttaatt
     2821 tagattttgc atacctagat agatttaatg cttttgacag ttgcttttca ccattctcaa
     2881 ctagattaac tctagcacca tctatacttg ccataagcaa ataagatgct gatgttgatt
     2941 gtagcatatt gattgattga agaacctttt caaaacttac attatctcta ttcaataaga
     3001 gtgctgaaga ttgtgtcaat gctcctccag ttttatgtat acttacagct accatgtcag
     3061 ctcctaaact tattgcagaa ggaggtaaat ctaaatgaaa tggaaaatgt gcaccatgag
     3121 cttcatcaac taacactaaa acattatttt tatggcatag ttctataata ctctcaaggt
     3181 ctgcacaaac tccatagtaa gttggattaa ggaaaaataa tgcttttata ttacaatctt
     3241 tttctatctc tgttctaact ttttcaagag taatatttaa acttatacct agtttttcat
     3301 caaattctgg ttgtataaat attggtattc ctccacaaag tattaacgca tttattactg
     3361 atttatgtat atttcttgga agtaatactt tttcacctgg ttttataaca ctcaaaatca
     3421 ttgcatgtat tgcttgagtt gtgccattcg ttataaagaa tgcctcatca gccatatatg
     3481 cttgtgctag caaatcttgt gcatttttta taatcccatt tggcgcagat acattatcca
     3541 tagttggtga tgaatttata tccattttca tgagactttc acctagatat ttatttaata
     3601 tagctacacc tctatttttt acatgtccag gcacatcaaa acaagctata tctttctctg
     3661 agtattcctt taacgactct aataatggag cacactcata gcttaattca actgcatttg
     3721 caaactcgct atccatgatt tcaaattcat ctcctctcta tattcaaata tttttaatat
     3781 ttattattta ttatttctat tttttatttt tacttttatt aaactcatga tatttattat
     3841 attaacatcc cagcattttt acaagtgttt ttttgaagtt actcaaaaac atatacatta
     3901 gctatatcaa tatttataaa ctttttaatt ttttgttgtt tatattaatt tttttaaaac
     3961 ttagtattta taaactttct tattttttat tattttggtt tttttacttt tttgagtttt
     4021 agtaagcttt tgagtttact atttttaatt tataagtatt ttattactaa acttttatat
     4081 tattcttatt tcacatatca aaattcttgg tttagttgga ctaaataatt ttcctatttt
     4141 tgtattttaa ttttaatata aaatttatta aattttttaa ttgataaaat aaattctata
     4201 tttatgatat taaaattcta taagttcatt gatttatata tgttaattta aatacattat
     4261 tctatcgtag tgccttagag tttttatttg tatttaaagt taaatttatt cttgtttttc
     4321 ctttaatatt taatagtaaa acaacaaaat tataaaaaaa ataaagagaa actttataaa
     4381 agcttctctt ttttcatctc tgctataggt atcgttttcc aatgttctct caaaactctt
     4441 tcaacatttt ctaaatcatt ctccctcata gattttacta cttcaatatg ttgattattg
     4501 ctgtatgtca acattttata taactcatct tcattatcac tagtatatga ctttgacata
     4561 aaattatatc ttaaagagtt caatagattt actaacacct gattatctga tttagttatg
     4621 tatatatcgt gaaattcatt acttaatttt aaatagctat tgtaattttt atactttata
     4681 gagaccgcca tcatttctgt taattcttcc atttttacta ggtctgattc agttaaattt
     4741 tgtaatgctg aagaaccggc taacgcatcc aatactccaa ttacggaata ggtgtctaat
     4801 ttctcctttt cctgaaattc ttttactaca aatcccttat taggtatttt ttctagtaaa
     4861 ttttcacctg ctaacctagt taatgcttct ctcgctggtg ttctactaac tccgatagat
     4921 ttacaaatct cagattcagt aattctctga ttagcttcat attctccatt ttggattttc
     4981 tttgatatat agtcatatac ttgagttgta agtggatcta ccttcataag acgttcctcc
     5041 atattaagat tataaaagtt aaatctccct acaactttgg tagagagttc agttttatct
     5101 tactaattta tataatatca caattatgat attttttata cttctttgta atattttgaa
     5161 atactaaaat tcttatgata atttatacaa aaaaagtaga aaaagttttg ataaaacaaa
     5221 actctttcca cattcacctt attttctatt tatttttcta aaaaaagata tttaatttac
     5281 tctaaaaatt ctaaatgatt tagagtctaa atctactttc aactcattat tttcaatttg
     5341 tatagtacta tttgcatttt taagactata ctttataggt atttcctcaa taaaactact
     5401 ctctatacat aatgatatac tttccacatt ttcacttcta tttactaaaa ttaacattct
     5461 atcattattt tcattaactc taataaaaga aaatacagaa tcattattag tatatataaa
     5521 ttctgtattt ccagaactta aaagtttatt cttatttcta atttttataa catctctata
     5581 aaaattaagc atatcttcgt cttcattttt ccatggataa gttcttctat tatctgggtc
     5641 aacacctcca caaagacctg cttcatctcc ataatatata tatggtactc cttcaaatgt
     5701 catctgtata gctacagcaa gcttcactaa atctacatca tcatttaatt ccgttttagc
     5761 tcttgtaaca tcatgtgttc caattaaatt taaattagac ctaaatgatt cttttggata
     5821 attttcttta atctgcatat atctattaca aagttcatat gaattaattt ctccttttaa
     5881 gaaagaaaac atgttatttc taaaaggata acccataaca gaatctaatt cttcacctaa
     5941 taaataactt cttctctgac catagctaat cttatttgat gcatcttccc atacttcacc
     6001 tataagaatt gagtcatcat ctgccgtttt taattccttt tttaactctc ttataaactt
     6061 agttggtaat tcgtctgcaa catctagtct ccagccctta atacccatat ttacccattt
     6121 atttataacg ctatcattgt catatattat ataatccata tagctatgtt ctaattcatt
     6181 tatatttggc aatgtcttaa catcccacca acttttatat ttttgaggaa attcttcaaa
     6241 catataccat gaataatatg gagattcttt agattgatat gcccctaaac tattatagtt
     6301 tccatacata ttaaaatatt tactatctgc tccagtatga ctaaaaactc catctaatac
     6361 tattgatata cctttttctt ttgctttatc aataagttct ttaaatgtat cttcatcccc
     6421 aaacattggg tcaatttttt tatagtcacc tgtatcatac ttatgattac tagaggcttc
     6481 aaatataggg cttagatata gtatacttac acctaatttt tttaaatatc caagtttatt
     6541 gattatccct cttaaatttc caccatggaa atcccatctt ataacatccc cttgactatt
     6601 ctttatgtac ataggtgtat cttcccaatt tccatatatg aaactatttt ttttaggatt
     6661 atcaacctta ccactacgat ttccattatt gaatctatct acaaatatat gataaagtat
     6721 tccttctttg taccatgttg gtactttaaa atctttgtaa acagtgattt gatatttatt
     6781 aatatcacta taattatatt cacaagaata tccattatct ctgttttttc cataaaataa
     6841 agtctttatc tgaccatcca tttcaacatc aactttaaag taataaaaat aaacacctgt
     6901 accatcaaac ttttcaatct taccacaaaa gcactttcca agtttatcat tatctaattc
     6961 ttcatttaaa gttattgttc tcatttcttc ttctctattt atttctaggg aaatagactt
     7021 gatattgtat ccctcattta ctttaacaca aatggtcaat tcctcatcaa attttaaagc
     7081 tccaaacgga gccttaaaat ttttatccca agagttatat tctattacac tttgcattta
     7141 atcacaccct tttaaaccaa atgtcttttg catactcaga aattgttcta tcagaagaaa
     7201 aaaatccaga gttagctata ttaactaaag acattttatt ccatttttct ttatctctat
     7261 ataacctgtt tatatctgct tgagcttgac cataattttc aaaatctctc aatacaaaat
     7321 actcatcatt gtaagtagtg agtgaattat aaatacttct tccttcttcg ccaagattag
     7381 gaataaatcc atttattaaa tcatctacta ccctttttat atccatatta gaatgatata
     7441 ggtcaagtga agaatatcca ccatatttat tataatttag tacttgttct gcactaagtc
     7501 caaataaaaa catattttct ttaccaacct gttcacatat ctctacattt gcaccgtcaa
     7561 gtgtagccaa agttatagca ccattcatca taaacttcat attacttgtt ccagatgctt
     7621 ccttagttgt agttgaaatt tgctcactaa catttgctgc tggtattatt atttctgcta
     7681 atgatactcc ataattctct aaaaatacta cttttaactt gtcctttact ctaacatcat
     7741 tatttatagt acttgcaaca gaatttataa atttaattat acatttagcc aaataatatc
     7801 ctggtgctgc ttttgcgcca aatataaaag ttcttgggtc aagattcaaa ttaggattat
     7861 caagtaattc atgatacata tgaagtacat taaatatatt cagtaactgt cttttatacg
     7921 catgcaatct cttaacttga acatcaaata tcgagcttgg gtctacattt aaatcgtatt
     7981 tatcttttat aaactttgct agatttgctt tattattgta ttttatatca tcaagtcttt
     8041 gtaaaacaga ggaatcattt ttaaattttt caatattttt taattgtaat gtatctttct
     8101 tccatgaatc accaattaaa tctgtaatta aattgctaag ttgaggattt gaacttataa
     8161 gccatcgcct atgtgcaatt ccattagtct tattattaaa tttatttggt tcatcttgat
     8221 agaaatcttt taatacctct gtttcaagaa tatgagtatg aagcttagca actccattta
     8281 cactatgact tgtgacaata cataagtttg ccatattgat attgtcacag tctattatac
     8341 tcattctttt tattctatct tggtcatatc ctttattatt taattcctct acatatcttc
     8401 tatttatttc ttctattatc atataaattc ttggtaatag ttctttcatc atacttacag
     8461 gccatttttc cattgcttct gacattatag tatgattagt ataggacact gtttttttag
     8521 ttatttccca tgcttcatcc caagataaat tttcttcatc aagcaaaatt ctcataagtt
     8581 ctggtatgca taaggtagga tgtgtatcat ttatatgaat tgctacctta tcgaataaat
     8641 tattaatatt taatttgttc tttttatatt ttcttattat atcttgtatc cctgcactta
     8701 caaaaaagta ttcttgtttc aacctcaaca acttacctgc atagtttgaa tcatcaggat
     8761 ataatacctg tgatatttcc tcagtataat acttatgttt taaagcctct tcatagctac
     8821 cagaataatt tagagcattt gaggtaagtt caccaaaatc tctctttggt atttcactct
     8881 taaacaatct taaagtattt atacattggt tttggtatcc gattattggt atatcataag
     8941 gcattgccat tacaggaagg tagtttttat gaattacttt taaatgacta ccttccttga
     9001 ttaattctac ctcaccacca aacttcacca ttgttgcttc atttggtctt acagtttccc
     9061 atgcatatcg tccttctgta agccagttat caggcacttc tacctgataa ccatttacaa
     9121 atttttgttc aaacagacca tatttatacc ttattccata tccttgacca cttatgttca
     9181 aagatgccat agaatctaaa aagcaagctg ctaatctacc aagtccacca tttcctaagg
     9241 ctgggtctac ttcagcttca attaaatcat ccaagttgat tcctaattca gataaacctt
     9301 ctctaacttc ttcttcaata tttaaattta ataaattaga ttttaactgt ctccctatta
     9361 aaaattctaa actaaaataa taaacttctt ttttcttatc taactttgta gcaacccatt
     9421 tttttgctat ctcatctttc aatagactac ataatacatt taacaattgt tcatcagtag
     9481 cttccttgat agattgtgca tataagctat acatttttac ttcaaatttt tgcttgaatt
     9541 tctttttgct tattgttacc aaaaaaacca ctcctttaat cacatatgtc tctatatgtt
     9601 tctatatact ccttagctga ttttttccaa ctattatctg ttttcattgc attttcaact
     9661 aatttaatcc atttttcttt gtccttaaat actttgattg catttttcaa acagaaaaac
     9721 atctcatgag cattgtaatt tttaaaacta aatccattgc cttctccagt aaatttatta
     9781 taaggtgtta ctgtatctct aagccctcca gtctctctaa ctattggtaa agaaccatat
     9841 ctcatagcta acatttgacc tataccacaa ggctcaaata atgatggcat taagaacata
     9901 tcacttgcag catatatctg ttgagccaat gatgcattaa aagtaattct agctgatact
     9961 ttatctgaaa aattagaatc gtaatagttg aacattgatt gatattgatg ttctccagtt
    10021 cctaaaacga caatctgtaa atcttctctc ataagttctg gcatcatgta tgctattaaa
    10081 tcaaatcctt tttgagaaac taatctcgaa actataccta tcaacggaat agatgaatct
    10141 tttttaagtc ccaatatatc ttgtaatctc aatttatttt ctactttttt gtcaattgag
    10201 tctacatcat aatgaacaaa tatatcttta tcttttgcag ggtcatttaa atcataatct
    10261 ataccattta atataccttt taattttcct gactcttttc taagtaatcc atctaattgt
    10321 tcaccataaa aagatgtttg tatttcattt gcataagtag gactaacagt tataatttta
    10381 tctgcaaaat ttataccagc tttcataaaa tttattgagc cataatactc tatatctcca
    10441 ttatcaaagt atttttgtgg taagtccaat atatcatata aaacatgctt atcaaataca
    10501 ccttgatatt ggagattatg tatagtatac atagttttta tatttttata cccctcaagg
    10561 gttgcatatc tttcttttag aattaatggt aacatccctg tatgccaatc atttatatgt
    10621 attacatctg gataaaaatc aaatctactt atagcttcta aaactgcatc tgtaaagaaa
    10681 gtatatcttt ctgcatcatc tccatatcca tagatactct ttctttcatc ttctcttcta
    10741 aaataaaatt cattatctat aaagtaaaat tttacaccat ctaattccat ttctaaaaga
    10801 ccacagtatt gatttctcca tccaacacgt acactaaaca cagctatttc ttttagttga
    10861 tcttttaaat aacttggtat agttgaatat ttgggcatta ttacccttac atctacacct
    10921 tcttttttta attctttagg caatgcataa gaaacatctc ctaatcctcc agtttttgca
    10981 aagggccaac actctgctgt tacataaaaa accttcatta gtcattcccc cttctaaaaa
    11041 atttatttat atatttgtat tcttttccac tacaagagga tatttttcat ctcctcttaa
    11101 ttctttccca tttgatacac tcgtattttt atctaatatt gcattatata gttttgcatt
    11161 tgactttatt acacaatttt gcattactat tgagttctct ataactgttc ctttttcaac
    11221 atttaccttt ctaaatatga tactatcttt tacagtacct tctattaaac aaccagatgc
    11281 tataaagcta ttttctactt tagcactatc tgtataaatt gtaggtgatt cattcttttc
    11341 ttttgtaaat atctttcttt cagaatataa taattcatct gcaacttcta aatttaataa
    11401 atctttgctc atttcaaaat atgattcaac agaatttaca cattttagat atcctgtata
    11461 ttcataggct cctattttca tgttttctgc ttcttcaata ataaattctt ctaaataaca
    11521 ataattgcct ttatttacaa tgttatatat acattcaaca aaatcttcac gcttcataat
    11581 atatgtctcc atacatatgt ttgctctagg gaacttacct aaattatttc ctacatttat
    11641 taccctattg ttactatcta aatttagagt taagttacca gcaaaatctt tatttgcatt
    11701 atttacattt ttatatatta tagttatatc attatgagat tttttatggt attccaatgc
    11761 ttgagaataa tttaaattgc atagcatata acttggagct attaaaatat attcttcttc
    11821 actcttttct atataatcta gattagctaa gatagtatat atatcacctt ctctatgtga
    11881 gtaagtattt ctatacttag tgttttctgg actaaaaatt gataggccac ctttttttct
    11941 acttaaatcc caatctttac cactacctat atggtctgtt aatgatctgt atttttcttt
    12001 tgcgaatatt ccaactttag tgattcctga atttatcata ttagataaag caaagtctat
    12061 tattctatat cttccagcta ttggtgtaga tgctattggt cttccatagt taagtttgtt
    12121 tattgctggg tctccttttt tgtttaaatt tattatccct aaacattcat ttctcatctt
    12181 aaagacctcc ttctattaat acgcatctag gttcgatatt ttcatactca gaaactacat
    12241 ttatttcatt atttacattc tttatctgaa cattatcatt tatagttgca cactcaccta
    12301 tcatagcttt ttctatagtt acattttcac ctattacaac atttggcatt attactgaat
    12361 caattacttt acttccttta ccaacaacaa ctccatgtga taatacagag ttacctactt
    12421 cacctaaaat tctacaacca tcagctatca ttgatctatg aacatttgca tttttaccta
    12481 tatattgtgg aggcattgcc atagtatttg tatatatctt ccacttaggg tctgctaaat
    12541 caagtgtttc tggagatttt attatatcca tattagcatc ccatagactt tgtatagttc
    12601 ctacatctct ccagtatcct ttaaatggat aagcatacat tccaacatta tcttctaaca
    12661 ttttaggtat taaatttttt ccaaaatcat cataatttat ttctggattt ttttctgctt
    12721 ccttaaaata atttctcaac attttccaat caaatatgta tactcccata gatgccaaat
    12781 tgctcttagg ttcacttggt ttttcttcaa attcatagat acttgaatct tcatttgtat
    12841 tcattatccc aaatcttgaa gcttcatccc aaggaacttc aatcactgct attgtagctt
    12901 tagagccttt ttccttatga aattttaaca ttttgctata atccatcttg tatatatggt
    12961 caccagataa tatcaataca tattctggat tataggtatc tacaaagtcc atattttgat
    13021 atatcgcatg tgctgtacca ttataccaat ttccttcttt ttcattcata aatggttgta
    13081 aaacatagac accaccattt attctgtcca aatcccaatg acttcccatg cctatatgtg
    13141 aatttaatat caacggtcta tattgagtta aaacacctac agtatcaata ccagagtttg
    13201 aacaattgct taacacaaaa tctataattc tatacttacc tccaaatgat acagctggtt
    13261 tggcaattct ttttgtaaaa acacctaatc ttgaaccttg ccctcctgcc aaaatcatag
    13321 ctaacatctc ttttttcatt taatgacact cccctcatct agtaattaat atttataatt
    13381 gcatttttac ttttataaac tttatcagtc aataaatgtc gtgtataaat gttgcttaaa
    13441 taatacctta ataaaaataa aataatatca actatacaat tgatataatg tataccccat
    13501 aatggactta ccgacgtata cattattttc cataagcact atagtattta ttaatattca
    13561 attattggtt aaaaaataat acaaatttta ttttataaat ataaaaacat tttttataaa
    13621 tcctttgtgt catatgaaca tgcttatttt ttaatttgtt aaattcgtaa tagcaaaata
    13681 taatctaata tttgttaaat aattatctaa agaaaatcaa gtaattatta atcaacttta
    13741 ttttttaatt gatacttctt tgtctataat ttaaacaaaa ggatataaac ttttaaatta
    13801 tttattagtt ttcttagtat taatgtttat atttttataa atatatatta ataatataaa
    13861 tagactaact aaaaccatgc ttatttgcta tatgttttat attatattat ataacacttt
    13921 ttacattagt aaaggataaa ttgtataaag attctgttaa tttattttta taatttcatc
    13981 tttctaataa aaacaaagaa gaagacttaa aaatttataa gtcctcttct tttcaacgtg
    14041 catttttgtg ctatatttaa ttaattcgac ctttaatttc catatccttc ctatgataac
    14101 aaaactcttt tattttttta atgattcatt atcatttaaa acttctttta tatcaagtac
    14161 ttctttgtta tcatcactca taacttcctt tattcctttg aatgttccta ggaaattaac
    14221 tgcttctgaa ggtaaaacca gttttgttga cttaccttca gccatttttt caagagcttc
    14281 catagatttt aatgctagaa tattattgtc tatatcagcc tctttcattg ctgaaaaaac
    14341 taattttaaa ccttctgctg ttgccatttg agttcttttt atcatttcag cttcaccttg
    14401 tgccttagca atagctgtct gtcttatagc ttcagcttca ccttctgcca ctaatatagc
    14461 agattctttt tcaccttctg ctacacgtac catagcttct tttttggctt ctgctgttaa
    14521 tattgcagat tgtttttcac cttctgcttg aagtattgca gctgacttat taccttctgc
    14581 ttgaagtatt gcctctcttc tttctctttc tgctctcatt tgtttttcca ttgcaacttg
    14641 aatatcctga ggaggcatta tattttttaa ctctactcta tttactttta taccccattt
    14701 atctgttgct tcatcaagga tagttctcat ttttacattt attatatctc ttgatgttaa
    14761 tgtttcatct aaatcaagtt caccaattat atttcttagt gttgtagctg ttaaattttc
    14821 aatagcagct attggattag ctatctcaaa cacatatcta actgggtctg taactttata
    14881 atatacaact gtatcaatct gcatagttac attatcttta gttataactg gttgaggtgg
    14941 aaaatctatt acaatttctc taaggtcaat tacatatgcc attttatcta aaaatggtat
    15001 taagaaatgt acacctgttt cagctacttt ttgaaactta ccaagtctca ttattatacc
    15061 tactttagat tgttttataa ctcttataca agttaaactt attgctacga ctactactat
    15121 taatacaata cttaaaacaa ttttagtacc catactataa atcctccttt attctattgg
    15181 tttgtcacat taactgtggc gtctactttt ttaacaacta attttacccc ttcaattttt
    15241 aatacttcta ctgtagaacc tttttctatc ttttcaccat ctatagaaat agccgtccat
    15301 gtttcatgtt caactacaac tagacctgtg ttatttgaag aaatctcttc tgtaacaata
    15361 ccttttttag acatcattgc ttgtaaatta gtgttagatt tatagccttt atcttttttt
    15421 actatttttt tagtagctac gactaacatt gctatagaaa ttactgcaaa tattaaaatt
    15481 tgtaagaaaa tactctctat aaagctactt aaaaatataa gtattacagc tcctacacta
    15541 aaccatatca atgttaagct tggtgttaac atttctgcta ttccaaataa gactgctact
    15601 atcaaccata ttaacttcat actatctacc ctcttttcat atgaattata aaaccctata
    15661 taaattatat gtttatacaa tgtttttgaa tataaattta aattacaaaa caataaaata
    15721 aattaattaa ttaatagtat tatatcaaca tactttgtta aaattgttac aaagtagtat
    15781 caaatatcac caattatata tccaacaact ctttcattgt taatgaaatg ttacttatta
    15841 aatccgtagc atttaccgta tacattgctt tgctcaattt atctcctata tagccatgta
    15901 tatatgctcc actaactgta gcttccaata tatccatacc ttgacctata aatgaagtaa
    15961 tcattccaag caaacaatca cccattccac cagttgccat acagctattt cctgtaggat
    16021 ttatatatgt ttttttacca tctgttatga cagtttgata accttttaaa agcaccacca
    16081 gattatattt ttgagcaaat tcttttgcaa catctactct atgttctctt atatacccaa
    16141 ttgaatctcc tgtcaacctg gccatttctc ccaaatgagg tgtaattaca aatctatttt
    16201 tccattctaa aaacttataa catctgtcct tcataacgtt caatccatct gcatctaata
    16261 ctattgggca attagaattt tctactatct taagtaattt atcaaatgtt tgactattat
    16321 ctcccatacc tggaccaaaa ccaattgcat cactagaatt aagtaattta tttaatcttt
    16381 cttcttcaaa atttaaagtc attgcttctg taagtctaat agataccttt tcttgcacat
    16441 cttcactact aattaatgtt acaagtccac tcccactctt aacagcagat tcagttgcta
    16501 tgaaacttgc accataaaat ccttttgaac ctgcaactat agatactttt ccaaaatcac
    16561 ttttaaaacc atgcttatct cttcttctaa tattattttt tacaaaagtc ttatcagtta
    16621 tgaactcttc atcatggtat tttcttgtaa taaaatctgg aacacctatc ttttctacaa
    16681 ctacatcacc tataagtgtg ctagtgtcat agtttagaaa acctctttta taaaactcaa
    16741 agctaatcgt tttgtttgct ctaatacaag ttcctaatac atttccatta tcgctatcta
    16801 tacctgaagg aatatctata gaatatgtat ttttactatt atcgtttact atgtcaataa
    16861 cttctttaaa aataccagtt atatcacgtt ttaatccagt cccaaatata gcatctacta
    16921 caacatcact tttagatact ctatctttaa aaattgttaa atttttattt tttataatat
    16981 tttgtttctc aactttaata attttatcta cttcattttc atctccataa tttttttcac
    17041 ttaaatcatt tttattaata tttataatat taattcccat atttaaaagt acattgtaat
    17101 ttattttaga gcattcactt agtttttcaa gattacctac taaaaatacg tttacttctt
    17161 ttccatatgt atttagatgt cttgctattc caagaccatc tcctccatta tttccaacac
    17221 cacatacaac tgtataacta ttatacatgc ctatatccat atttttcatt gcagatataa
    17281 ccgcattttc catcaataca atcattggaa tccctacttc ttctacacat gcagtatcaa
    17341 catttctgct taatttagat gtacctatta gcataaatta tcactcctat aaagttaaag
    17401 acttcttaaa tacttaccaa aaatatctat tgaaatcttt ttaatcccat aaatatcata
    17461 aataaaatca ctaaaactaa gagttttgaa ataatttaaa ataacaaaaa attttgaatt
    17521 aaaacaatta tttaatttat tataccatat aatttaagtt attatgttga tttaaaacct
    17581 atttacacta attatctaaa tatctcttta tttttataat cttttatgac ttatttatat
    17641 ttttcatttt tataaaaaaa caataattaa gaatataact atattctaca tgtaaaaatt
    17701 tttttattta aactcaattt tctgataatt tgataatttt tcaaaattta tagttgactt
    17761 ttatttttta ctgtattaaa ctaattacta tacaaaacag aaaacaaaat tttcaaaatt
    17821 attaaattaa aaggagaggt aaatatgaag actttattaa acaaacaagt acgatttttt
    17881 agtagccaat ttagttaggg tttgtaccta agttaagaca aattgtcata acatagatac
    17941 aagcccctta ggattatgat ttttaaggat tgtatctatg ttggctatag taattgttgt
    18001 taaagttttt attttatcat cataatatag agccacatgg attatactgt gtggcttatt
    18061 cgaatttttg ccatacagtt atatatactg tgtggttttt ttatatcaaa atcatttttt
    18121 aaaatcaaat ttaaaaaacc atttaaaata ttttcaaagg ggtgttttat ttatgtcagg
    18181 tattatatct gtaatgacgc aaagtttaat tttatcgatt atggcactgg gggtttatat
    18241 aacttacaaa atcttagatt ttccagatat gtctgctgat ggtagctata caatgggtgc
    18301 ttctattgta gcattttctc ttactaatgg tatttctcct gtagtagcaa ctttaatggc
    18361 tatcttatgt ggttgtactg ctggtcttgt tacagggatt cttcacatta agtttaagat
    18421 atctaattta ctttctggta ttttagttat gggaatgcta tactctatca atttaagaat
    18481 aatgggaaaa tcaaatattc ctctatttag ctttaaacac ttattcaatg gggaaatatc
    18541 tcctatagtt ttagccttag cttttgtatt catctgtaaa gtccttttag atttattcct
    18601 aaaaacaggt cttggataca ctttaaaagg tgttggtgat aactctcaaa tgattaaatc
//
LOCUS       DAEPUT010000079        18523 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.081, whole genome shotgun sequence.
ACCESSION   DAEPUT010000079 DAEPUT010000000
VERSION     DAEPUT010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18523
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.081"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..210)
                     /locus_tag="KRL22_002965"
     CDS             complement(<1..210)
                     /locus_tag="KRL22_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1273416.1"
                     /translation="MLKIEHLKKSYENFSLDCSLEVKKGHVTGLIGQNGAGKSTTFKA
                     ILGLISFDSGTINILGKSLQDFTAKD"
     gene            complement(213..584)
                     /locus_tag="KRL22_002966"
     CDS             complement(213..584)
                     /locus_tag="KRL22_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004611555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1273417.1"
                     /translation="MKIIINHSSMIPIYEQIVEQVKALIRNGKLKENDNLPSVRSLAK
                     ELKISALTVKKAYDSLENEGFTVTIHGKGTYVTATNTELLLEEQKKELESDLERVIQK
                     GRCYGISDEDIKKLFELILEG"
     gene            complement(706..1608)
                     /locus_tag="KRL22_002967"
     CDS             complement(706..1608)
                     /locus_tag="KRL22_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1273418.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDQHTTHEKEIIELRLQDTNGIENFVKNFAKSYYTWNNSKEAIEVRTQAISG
                     YLTKELQDLNIDTIRTDIPTCSTVTDVIVWHIEQSGTDTFSATYEVDQQIKEGEKTSN
                     VKATYTVKVHIDADGDMVIVQNPTLAPAIEKSDYEPKTPEADASVDADTVNDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLEPIGRDYLYSELVNPIFTKDGDNVKVKVGVKFLDN
                     QTKATQISQYELVLHKDSNWKIVG"
     gene            complement(1625..2632)
                     /locus_tag="KRL22_002968"
     CDS             complement(1625..2632)
                     /locus_tag="KRL22_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH1273419.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYAREYGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGIDDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLTQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGTYVTHVAIYVGNNQMYHAGNPIGYADLSSSYWQQHLIGAGRVK
                     Q"
     gene            complement(2629..4824)
                     /locus_tag="KRL22_002969"
     CDS             complement(2629..4824)
                     /locus_tag="KRL22_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1273420.1"
                     /translation="MKERIKGAFTKKKIFHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTQNGFSSSGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEGNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNANDSQSMGRRIFRRP
                     YLYLAHRARRMERRLAGAVTAGGVAGAVAGSTISNRKPTRNTATKDSRGNTTSSMGQR
                     AGTKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKRGMVQE
                     QQSRQSGRLEKQEQHRQNIADKRMELQKAQEARQAQRKADGSATTGATRPHERPATAS
                     TIPKPSAKKMQEVKRPATATTSKASEPVKTTVIKERPLSSGVSDRKATQPAQPVHKQN
                     VEKVVSQETRQNYTKDRRTEVQQTQSVQKNQQTTEKSRNLVTKKGQKKK"
     gene            complement(4824..7274)
                     /locus_tag="KRL22_002970"
     CDS             complement(4824..7274)
                     /locus_tag="KRL22_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1273421.1"
                     /translation="MFPIKYIDNNLVWNEDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLKEVACQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFTEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLMEHLYGRDGVAYEDYEYQLPKKNLQKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGETTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSDSRGLLHVIDELRREDTPISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(7252..7650)
                     /locus_tag="KRL22_002971"
     CDS             complement(7252..7650)
                     /locus_tag="KRL22_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1273422.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDIPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVKYVPDKIY"
     gene            complement(7768..8271)
                     /locus_tag="KRL22_002972"
     CDS             complement(7768..8271)
                     /locus_tag="KRL22_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1273423.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIAIGEYVSIEKLNEMYEMIEELPDYIVECLDEFISHYGSLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGYFIETSR
                     GMCEIPY"
     gene            complement(8289..8792)
                     /locus_tag="KRL22_002973"
     CDS             complement(8289..8792)
                     /locus_tag="KRL22_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1273424.1"
                     /translation="MQETRVLVETRGTTGEETISYWFELPIDVDEFEEKLGVGAESGE
                     YRIIEKVLPYADEVQEHTSVYQLNELDFMYRQLSSDMQEEYVSLLTVFENLEALYICR
                     NVITVYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(8711..9007)
                     /locus_tag="KRL22_002974"
     CDS             complement(8711..9007)
                     /locus_tag="KRL22_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1273425.1"
                     /translation="MSDIFKDMQSKVGCDYISDLPSYKRKVWHEMKRLNPADYEERQL
                     EDFSKYVFGMSYQTIKDVMKQQKGREEQCRKQGCWWKREEQLAKKQYHTGLNCR"
     gene            complement(9104..9424)
                     /locus_tag="KRL22_002975"
     CDS             complement(9104..9424)
                     /locus_tag="KRL22_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005602893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273426.1"
                     /translation="MEGYIMIGFSIMMWFCSALLIFVSFSLLKGNYSSVHGKVFETTN
                     DRKGYAKALGKPVLLIGICLLFSGVIAVILPKDYAISIAVIFILFIAVICSIWLYKIQ
                     KRFS"
     gene            complement(9589..9810)
                     /locus_tag="KRL22_002976"
     CDS             complement(9589..9810)
                     /locus_tag="KRL22_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273427.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(9812..9946)
                     /locus_tag="KRL22_002977"
     CDS             complement(9812..9946)
                     /locus_tag="KRL22_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH1273428.1"
                     /translation="MWVLLKDFLLVSMGMGIGVVLMCILNVGKEADYEMKQLKESEDK
                     "
     gene            complement(9959..11155)
                     /locus_tag="KRL22_002978"
     CDS             complement(9959..11155)
                     /locus_tag="KRL22_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBH1273429.1"
                     /translation="MVLNEEQRIKELREKRIAYGISQGRLAVASGITREYFNKIESGK
                     MKPSKELLETLHKELARFNPEEPLTMLFDYVKIRFSTLDIQHIIKDILKLNINYMLHE
                     DYGRYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LVDGGVMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKFYQSGELIKHREDDR
                     EYMGRTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFVDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEKQAVLSEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(11305..11694)
                     /locus_tag="KRL22_002979"
     CDS             complement(11305..11694)
                     /locus_tag="KRL22_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273430.1"
                     /translation="MLDCFLNYSVNPNLRFHSRIDKIIDDVIREKINIPHKFRMRLES
                     RHCIESRIIYFRFRVLDKSCLQCNVFLKGLSDEMKEALSDERIDFAVLYEGIQGSQQD
                     TDTDDKDGFCGSQPQVPFLADGACPVR"
     gene            complement(11789..13180)
                     /locus_tag="KRL22_002980"
     CDS             complement(11789..13180)
                     /locus_tag="KRL22_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1273431.1"
                     /translation="MRMIWNKGHRIRASDKHLVYHFSIGMLLFIFVTVLLLLNMKQLM
                     CTDWEHFSLLENGLTLSPYNFITIGIATGVCALVAFGYYRFCYDGFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLKLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNSDLADLGTVMPNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGRLAQERQ
                     AMPEQQGKEDVIE"
     gene            complement(13279..14043)
                     /locus_tag="KRL22_002981"
     CDS             complement(13279..14043)
                     /locus_tag="KRL22_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008687118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1273432.1"
                     /translation="MDSWFTVEQIDQDTFVISEYRHWEETHCYLLCGTKRAILIDTGL
                     GVSNIREVIDGLTKLPVTVITTHVHWDHIGGHKYFRSIAVHEAEKEWLSVKFPIPLQV
                     VKNNIMCNPCDFPSDFNVEKYQIFQGVPQMILHDEDCIDLGNRKLVVIHTPGHSPGHC
                     CFYEADRKYLYSGDLIYSGCLDAFYPSTNPQEFWKSVRKIQSLKISRILPGHHHLSIP
                     VTIIDKIETAFHNLSNEGKLKQGNGIFSYEGFQIHI"
     gene            complement(14145..14528)
                     /locus_tag="KRL22_002982"
     CDS             complement(14145..14528)
                     /locus_tag="KRL22_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1273433.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTFGGADVDWYVKAED
                     IVLKNKGNQNAGNPQNHAPQGQPKK"
     gene            complement(14544..14870)
                     /locus_tag="KRL22_002983"
     CDS             complement(14544..14870)
                     /locus_tag="KRL22_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1273434.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPVFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKKFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVADDI
                     VAVEEK"
     gene            complement(15109..18153)
                     /locus_tag="KRL22_002984"
     CDS             complement(15109..18153)
                     /locus_tag="KRL22_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH1273435.1"
                     /translation="MKKILKRLCTGFLALATVVTALPSTPVHAESKQYWTESAERVGI
                     IEKVMNDGSIGSTFNEGYMKVEGETAYCIDINTDFKNGYKTRTDASTRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYKCGGYIYSGEGQELGQFWAKLNVGNAKLQKVSSNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDENGNTDVIEVTAGTVYIKELSAPAGYNVDKT
                     VYPLTIKAGETATLKVSDTPKVTDTLIELFKIDMETQKDNPQGNASLAGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDGITHYITKLADAYKVSGDSFYMQDGKAVLPL
                     GTLTVEETKAPNGYLLDGAYMQTGDKSEQIKGLYVTQITGDGDLAVLSGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNDNSVLVEGKLYKKNEVVKTIR
                     TDIEGIASTSADLLPYGKFRIVESEAPNGYLTDGAKPIDFVITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSADWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEVTIVDTVKLDGLKKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFVADEEEMKVEISYTFNASALGGKNLVTFEELYD
                     FSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKEVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENAELLINGKRVESDYTFTADSETMKVEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDKGQTITFKEKPEEPEKPETPPTPEKPN
                     RPSDSPKTGDSTNVMAFIVMLLASVGGLAGTYLYKRRKMKKS"
BASE COUNT         4912 a         4294 c         3435 g         5882 t
ORIGIN      
        1 gtcttttgca gtaaaatctt gtaatgactt tccaagaata ttgatagttc cactatcaaa
       61 ggaaattagc cctaaaatag ctttaaatgt tgtgcttttt cctgcaccat tttgaccaat
      121 caaaccagtt acatgacctt tctttacttc aagagaacaa tcaagcgaaa agttttcata
      181 actttttttc aaatgctcaa tttttaacat atctaaccct ccaaaattaa ctcaaatagt
      241 ttttttatat cttcatcact gataccgtaa catctgcctt tttgaataac tcgttctaaa
      301 tcactttcta attccttttt ctgttcctct aataaaagct ctgtatttgt agcagtaaca
      361 tatgttcctt ttccatgaat tgttaccgta aacccctcgt tttccaagct atcatatgct
      421 tttttcacag ttagagcact tatttttaat tcttttgcaa gagaacgaac agacggaaga
      481 ttatcatttt cttttaattt tccattccga attaaagctt taacttgttc tactatttgc
      541 tcgtaaatag gtatcattga agaatggttt ataataattt tcatctcaca gcttctttct
      601 gtataaacag tatataacag agtaacgctg ttgtcaagtg ttatatggtg tttgtacaga
      661 aagtgaagcg tgcaaatctc atttaggaaa tgcacgctat ataatttatc ctacaatctt
      721 ccagttacta tccttatgta gcacaagttc atactgcgat atctgcgtcg cctttgtctg
      781 attatcaagg aatttcacgc ctaccttgac tttcacattg tccccgtcct ttgtaaagat
      841 agggtttacc agttcagaat aaagatagtc cctgccgata ggttcaagca catttcccga
      901 tacataatag gcaagctctt tttccgtagc tgtcgggtag agcttaaaga atgtttccag
      961 aaatgcggta gcgtcattca cggtatcagc gtctacactt gcgtctgctt ctggtgtctt
     1021 aggctcatag tctgattttt cgattgctgg tgcaagggta gggttctgaa cgattaccat
     1081 atccccgtca gcgtctatat ggacttttac ggtataggtt gctttcacat tgcttgtctt
     1141 ttctccctct tttatctgct gatctacttc gtaggtagca gaaaaagtgt ccgttcccga
     1201 ttgctcgata tgccatacaa tcacatctgt aaccgtggag caggtcggta tatcggttct
     1261 aatggtatct atattcaagt cctgcaattc ctttgtcaga taaccgctga ttgcctgcgt
     1321 ccttacttca atcgcttctt tgctgttatt ccatgtgtaa taggactttg caaagttctt
     1381 cacgaaattt tctatcccgt tggtgtcctg caagcgaagt tcaatgattt ctttttcgtg
     1441 ggtcgtgtgc tggtcgatag ccgtaaaatt cttatacacc ccaaagctca cgcttgcgat
     1501 aagcaccacc cacaacgcaa tcacggtttt cttatgtgtg cctaccttga cagtacgcac
     1561 ctttttttct ttgacatttt ctgtctgttt cttattcttc ttaaacatat ttttcaagtc
     1621 ctttctattg ttttactcgt cctgcaccga ttaagtgctg ttgccagtaa ctactactta
     1681 ggtctgcata tcctatcgga tttcctgcat ggtacatctg gttatttcct acataaattg
     1741 caacgtgcgt tacataagta ccagcgttat aggtagaatg aaaaaacacc aagtccccag
     1801 cctttgcctg cgagagtgga agatgttggg tagcgtcata ctgtgcttgt gctgttctcg
     1861 gtaaggagat accagctttt ccatagcacc attgcgtcag ccccgaacag tcaaaagaag
     1921 tgttaggatt gctaccgcca tacacatatt tccagccttg atattttaac gcttcattca
     1981 ttaccttttg tgccagctct cccgatacct gcggaacagt taaatactga ttgactaatt
     2041 ccacatagaa catatttcca tagccatatc gccagccccc gttctttgca acagctatcg
     2101 ggttggtgta ggttactttc tttccacccg acttctcacg agcgaagctc tctgcaaggt
     2161 taaaggtgtg ttttttccct tttcctgcca catatcccac atagccaccg ccatagttat
     2221 aagactgtat cgctacattc aaatcgtcga taccttgatt tttgcaggaa gaaagcaggg
     2281 acgcaaaata tttacacccc tgcttgattg agctttccgt atctaaagag ttgggcggta
     2341 gtcccagact ttctgaactc tgcataacat cttctgccgt accgccactt tctacttgaa
     2401 tgatagccaa tagcacattg acatactcgg aaatgccgta ttctctggcg tatttttcca
     2461 ccataggctg atgtttcaaa acttctgcgg ataagttcat acccgtaatg ccagaagaaa
     2521 aattgctgtt ctcgtcgtcg ctgtctgcac taatgaggac accaaagaaa agcaccagag
     2581 aaaagaggat aggaaacaga ctgccaataa tagcgatatg tttcagtttc attttttctt
     2641 ctgtcctttc ttcgttacaa ggttacggct tttctctgtg gtctgctggt tcttctggac
     2701 gctttgtgtc tgctgaacct ctgtcctgcg gtctttggtg taattctggc gtgtttcctg
     2761 cgatactact ttttctacat tctgcttatg tactggctgt gcaggctggg tcgcttttct
     2821 atcagaaaca ccagaagata acggacgctc tttgataaca gttgtcttga ctggctcact
     2881 tgcttttgaa gtggtcgctg tggcaggacg tttgacttcc tgcatttttt tcgcactcgg
     2941 ctttggaatg gttgaagctg tggctggtcg ctcatgggga cgggtagctc ccgttgtcgc
     3001 tgatccgtca gcctttcgct gtgcctgcct tgcttcttgt gccttttgaa gctccatacg
     3061 cttgtcagcg atattctgtc tatgctgttc ctgcttttcc aaacgtcccg actgtctgga
     3121 ctgctgttcc tgcaccatgc cacgcttgaa gtcagacacg ctggactttg ccttttcttt
     3181 tgcggaatac accgcataag cggtctgtgt cggcatatcc ttgatgtttt ctttgacagc
     3241 atttgccttg tctttcactt tatttttcgt atctaagaca gcacccacct ttgtgcctgc
     3301 acgctgtccc atgctggaag tggtattgcc ccgactgtct tttgtagctg tgttccttgt
     3361 cggttttctg tttgaaatcg tgctacctgc caccgcacca gcaacaccgc cagccgtaac
     3421 cgcaccagca agccgtcttt ccatacgcct agccctatgt gccaagtata gatatggtct
     3481 acggaaaatt cttcgtccca tgctttgact atcattagcg ttcaaagaga acatactcat
     3541 taagtcgccc agcttcatgt agataccagc gaaacacact atctgtaaga acgctaccat
     3601 aaagaacgga tagtccgtgg atatgttata aaacatactg gaaatgctga acgccaccgt
     3661 tacaatgagc gttattcctg cccgtgtcat tatggtatta aacaccctta cgattgcctg
     3721 ctttgccatg ctttcataac tcggtatcat ggaaagtaaa aagctgatag gtaaaaacat
     3781 tgcaaagata ataaaaagta tctggctaaa caacatcatg cccgtaagca agaatacaaa
     3841 tattgttatc cctaagttga agaacagtag gaagaacacc atacctaaac ggttcacgac
     3901 ctgcggtatc gtcagattgt tgttgtcgtt gccctcgatt tctgttttca cgacttcctc
     3961 tctggttttc ccgtcctcgt cctctgggct tgccgataca agagcttcta cacggtctgt
     4021 cccgatttcc tctgcgttgc tgttaccgaa ttgaagcaag agccacggtt gttccacttg
     4081 aatagaaaat aggctgtccc gtatcaagtc cacgctgtcc ttgccctcgc tgtcagagtt
     4141 ggggagcatg atttttgttc ccaaatcaag tgaagcggta ctgatgtctg atgaaaattc
     4201 atttatcttt ttgatgtaat cgggagcata ggcaataaac gaagcggaca acacaaatac
     4261 cacaacaaag ttgataacag catgaagtgc tttgctggtt tcccgtttga taagtcccgt
     4321 atatgcaaca taaagtccta ccactaagat aatgagaagc agaaaaccaa catagaagcc
     4381 agaactggaa aaaccgttct gtgttacacc tgcaagggtc tgtatgcttt ttccaatact
     4441 gtctgccata tcgttgatga agtccagctt ataggcttcc tgcaccacat accctgtggc
     4501 attgcttaaa taaaggctta tcgtccagac aaagttggta atgcagtaaa gcccgtactg
     4561 taccgatttt ccgataccgt ccagccagtt ccacggaagc cacgaccagc tattatccac
     4621 ataaaaatca agctggtagt tggaaagggg gtattttgag taaagatttt ctgcgtttat
     4681 ggtatcgtcc acaagccccg ttgcatgagc caccgtcccc agaagtgaaa gcaggataag
     4741 ggagagtgcc accacgaaca gagccatttt gagaaagtgg aaaatcttct tttttgtgaa
     4801 cgcacctttt atcctttctt tcatcactcc acctcatttc tctgtacggg cggtctggta
     4861 tcaaaggcgt gtagcagttc ttcaaagacg gggtgtatct gcaccacacc gacacgcccg
     4921 tataagtcct gcaataagca ttgtccgttc tccaaatcac gaagccgttt ctggttgttc
     4981 tcgtcgtcct tgtcgatacc gaaaaattct aaggtctgct ttatctcgtt gatgtcagta
     5041 gaacgaaagg caaacttcaa gccgatattg tttttcagac tttcctttga cacgtcgcca
     5101 gaagattgtg taacaaaata aacgcctgcc tgcatagctc gtccagcacg caccagctta
     5161 tttgataagg tttcgccttg tgccacattt aagaacgccc acgcttcgtc caaatcgaca
     5221 atcttaaaaa tgcttctgtc cgaatggata aaatcaaggg caaaggtact aatcacaatc
     5281 agcatagata ccgacaataa ttcaatggtc gtgtattcct caaaagtggt atctttatct
     5341 ggcaacacaa ggtcggctac ttgaatgata ttgagctggt tatctaaact aattgcattt
     5401 tccaccgtac cgtctgaaaa cagcaggtgt gcaaagtcgt agtctgtgaa gctgtcgata
     5461 tggtctgcga tatttcttga tatgggtgta tcttcacggc gtagctcatc tatcacatgg
     5521 agcaagcccc gactgtcgct ctgggtaacg gaacgcaccg ccttacgaag tacggggaat
     5581 ttctcgccgt ccctagagga aatacccgta aggaatgtta agatgtcgat tgccagactt
     5641 tcagcgtctt ttacattctt cataatcaca aatgggtcaa gaagtcctgc attgtccttg
     5701 tcgctggtaa gatttacgat attgatttca tgtgcaatct ctgggagtgt ttctttccag
     5761 ttaccacgct cacttttagg gtctaacaga agtgcttgac cgccaaacag caccgcataa
     5821 tataccagaa gattgttaca gaacgatttc ccaccgccaa gcgaaccgac aaaagcagac
     5881 gctaaagcgt tggtaactgt accttttaca ccttgactgg caagggacgg ttgcaggtac
     5941 acatttcttc ccgtatcaac agaatagccc atatagatac ccgtagtttc tcctaactgc
     6001 tgtgtcgcac caaaaccaag ccctgctaga aaatctgatt ttacatactg cacatagtca
     6061 ttgatatatc gcttgctggc tggtaaaaat tcagaatgaa gccccagcat atccccagca
     6121 ggacgcacca gctttacatt gaggtcatcg taaaagtcct tgacttcatc acaacggcgt
     6181 ttcagctcgt caagatcggg tgcagacacc cgaataacgt agcttaactt atacatactt
     6241 tctttgctct ggtctaagtc tgtttccagc tcgtccacgc tgtctaaagc gtccaccaca
     6301 tttgagctgg tttcacttcc agcttgatag gcgtgattgt caaggtcttt caattccttt
     6361 ttcttgttgc ggacggttgt taatgctttt cggttctcca cgatttctac attcatggaa
     6421 gtatcaacgg ggaatgtgaa ttgctgttgc tggaaataga aaatttcgct tgacggaaaa
     6481 tcaagctcgc ctacaatcgc attgacggta aaataggaca catagctttc cttatcctca
     6541 tgttccaagc gtaaatatcg ctggctttcc tcaatcacac atcttgtcgg acggataagg
     6601 tcgtagtatt ttatcagcgt ttctttctgc aagttcttct ttggtagctg gtactcataa
     6661 tcttcataag cgacaccgtc cctgccgtaa agatgttcca tgagataccc aaaatcattg
     6721 atttccaagc gacgcacctt aaagcgacgg gagattttat tttccagtaa cttttccatt
     6781 ttcatgtaac ggttgatttc atcattcggc atggaaacaa aatcattcat cagcgtgtgg
     6841 ttcacttcat ggagaaattc cgtgaacgtc agccacgccg attttttaat gttcttcaga
     6901 ttaagctgtt cttccgtaac catgagctta aagccaagaa aaaagcggta gtccacttga
     6961 ttgtccccaa tcatagatac taacgcttcg gtctgttcgt ctatcttctg gcaggcaact
     7021 tcctttaatt ttccagttac cagtttcttt gactgttcct gcatactgcg gattgagctt
     7081 tctgtggcaa tctgcaacgc atgaatttta ccctcacggg actgtgcgat aagctgtcgg
     7141 aaactgtcat gcacgataaa tttctgctct gcggataaga aagaatagtt gtacggtatc
     7201 agctcatagt aagcgaacac ctcattgtcc tcgttccaga caaggttatt gtcaatatat
     7261 tttatcggga acatacttca cactccttac tgccgtgatt gtttcattga gtatctgctt
     7321 atgcagtttt acggcttttc ctgcataagt gatttttggt cgcagggcat aggtaatctg
     7381 tgatttcaaa aagctgtacg gcttctttcc gtcaaaggtt ttctgcgaca tgaaccaagt
     7441 gagagcaacg ggaataccga agtatttgag aaatgctccc tcaatcatgg aaagtggggg
     7501 aatatcccca aacagaatga tgataaattc tgtaatcaca aaccatgtaa tctgtgtaaa
     7561 ggtaacggga aagggcaagt taaagtcatt gattgcatac aagacttttt ccacgttcca
     7621 gatacccgtg tagcttttaa tctttttcaa gttctttcag ctcctttcgt aagtttctaa
     7681 atagaaaagg acagccattt tcagactgtc ccttaaaaga gaaatacgct gtcagtagca
     7741 acaatgcttg tcgctgatct tccagcgtta atatggtatc tcgcacatac ctcggcttgt
     7801 ttcaataaag taaccgccca tatccaaatc tcgcccgtag gcttcatagt caatgtagtt
     7861 ctgtaagctg ggcggaatgt cgccaagtgc ctgcaattcg tctatgtagt agtaggcaac
     7921 atctgtcatg gtttcacagt cgggataata ataaatatcg tccttgtgtt ccacgacttc
     7981 ttccagcgac ccgtagtggc tgataaattc gtccagacac tctacgatat aatcgggaag
     8041 ttcctctatc atttcataca tctcattgag tttttcaatg gaaacatact cgccaatcgc
     8101 aatggggaag ttgtcggtat catggacagc gtattcctca tactgttcat tcaagccgat
     8161 tttttctttc acatcttcct cgtcaatggg gaacgtgaac caagcaccga ctaaatatcc
     8221 ctcattgtat ttgccaagat tagcaatgta aaccgccata tcatcaatca taagcaccac
     8281 ctcatttcct actctggcag ttcaaaaata ccgtgttctg ttactaaaaa tttcccgtgt
     8341 tcctgcaagt gagaagcgta ggcttcaaag tcaaagtaat attcttgaca gtcctcggac
     8401 agatgtttga atgtcgggtc attcatcagc ttttgccttg caacatcaat catgcttttg
     8461 cagtcgggat aaaccgtaat cacgttcctg caaatataaa gtgcttctaa attctcaaac
     8521 accgtaagca gtgatacata ttcttcctgc atatcacttg aaagctggcg atacataaaa
     8581 tctaattcat tgagctggta gacgcttgta tgttcttgaa cttcatcagc ataaggcaac
     8641 accttttcga taatacggta ttccccactt tctgcaccga cacctagctt ttcttcaaac
     8701 tcgtcaacat ctatcggcag ttcaaaccag tatgatattg tttcttcgcc agttgttcct
     8761 ctcgtttcca ccagcaccct tgtttcctgc attgttcctc acgtcctttc tgttgtttca
     8821 tcacatcttt tatggtctgg tacgacatac caaacacata ctttgaaaaa tcttctaact
     8881 gtctttcttc atagtcggca gggttcagtc gtttcatttc atgccatacc ttacgcttgt
     8941 aagagggcag gtcagaaata taatcacagc cgacttttga ctgcatatcc ttaaaaatat
     9001 cgctcatttc atcactccaa tctgaaattt tggtaagaaa aaagcagtca atcctaagac
     9061 taactgcttt gtgtgtatgg atatgaaatt gtcaaactgg gatttacgaa aatctttttt
     9121 gaatcttata cagccatata ctacaaataa cagctataaa taatataaat ataactgcaa
     9181 tagaaatagc ataatctttc ggtaatataa ctgcaatcac tccagagaac aaaagacaaa
     9241 ttcctatcaa taaaacaggc tttcctaatg cttttgcata tccttttctg tcgtttgtgg
     9301 tttcaaatac tttgccatga acagaagaat aatttccttt taatagagaa aaactaacaa
     9361 atatgagaag agcagaacag aaccacatca ttatactaaa gcctatcata atatatccct
     9421 ccatcaattc taattttctt agttctataa actgaaattt tgttatttca ttttttcttg
     9481 acactcgcta cattctttat cgtgaataga aataatgcca ccgcactaat ttgccgtttt
     9541 cttcatatcc atattatacc attctcatac caacaccaca ataaaatttt atgcaccgat
     9601 aatcttattg aacagctcta acagtacatc tttcacaccg ccagcattga ataccaaacc
     9661 gacagcaatc aaggcaacta ccaagaagcc gataagtttg gaaaactcac gcttgaaacc
     9721 taagtagata ccgataacta caatcgccat aagcactaag ctctgtgcgt tgcttaaaaa
     9781 ccattgatac aaattttgcc cgaaattcat gttatttgtc ctcgctttct tttaattgtt
     9841 tcatttcata gtcagcttct ttgccgacat tcaaaataca catcaagact acgccgatac
     9901 ccattcccat agataccagc aggaagtctt ttaataatac ccacattttt catcactcct
     9961 aactttctac taaatctttt gcaggggtcg tctgctgttt gattatcatt tcatgctttt
    10021 cactcaagac tgcctgcttt tcaatcgttt ccatgtagtc tgtaccgttt cccttatcaa
    10081 tctttttcag cattttcaag gtcggtgcta cctgcctttg tacccaacgc aatgtgcggt
    10141 ctaaggtata aggctctggc tttgtcgtta gtttcagact ttgccgatta tcgccgataa
    10201 accaagccca gcggtcattg agtttccagt catttttccg cttgtctggt tcttcatcaa
    10261 caaaccgcac atactggttg ataatagaaa aggcggtctg ttcagcgtca taataggtca
    10321 gcaaatctcg tactgcatag taggcacgtt catttctaag ccgtatctca aaacggttga
    10381 taatgtcggc ttcttccagc ggtgtcccta acttgacgta ctgctcatag tccttttcat
    10441 agatacaaaa atacacatca gatttcagtg aaccaagata aagggtacgc cccatatatt
    10501 ctctgtcgtc ctctctgtgc ttgataagct cgcccgactg gtaaaactta taacttctgg
    10561 actttccgat atattcccgt ttcctgcatt tttccgcaag ctctggaata tccaaaatgc
    10621 ccgtatggtc gttgatagca aggtcgatac gcttcataac gccaccgtct actaatgcgt
    10681 ccatgaggaa gtcataccag cttctttgct gtgccagcag ataactttca aactgcctgc
    10741 aaccacgccc ctttaactct aaaaggacac ctttttcttc gtcagccgac gtatagataa
    10801 agatgtcccc taaagagtaa tgctccgtat agctgtaacg cccgtaatct tcatggagca
    10861 tataattgat attcagtttt aatatatctt tgatgatgtg ctgaatatcc agcgtggaaa
    10921 aacgaatttt tacataatca aacagcatgg taagcggttc ttctggattg aaccttgcca
    10981 gttccttatg cagagtttcc aaaagctcct ttgacggctt catttttcca ctttctatct
    11041 tgttgaaata ttcccttgtg ataccagaag ccaccgccag cctgccttgt gagataccgt
    11101 aagcaatccg tttctcccgt aattctttta tccgttgttc ttcattcaga accatacccc
    11161 caatctgtaa agtgtgaagt tttttaaggc gacttcacag ccgatttttg ctagaaaacc
    11221 atgccagaag ctttatgttt cctatgtttt tcgtctattg tctatttgca aacgtacccc
    11281 tctgttagat accgaggggt ttaatcagcg gacgggacaa gccccgtccg ccaagaacgg
    11341 aacttgcggt tgagaaccgc aaaacccgtc cttgtcgtcc gtgtctgtgt cctgctgtga
    11401 accttgtatg ccctcataga gaaccgcaaa atctattctt tcatctgaaa gtgcttcttt
    11461 catttcatca gacaatcctt taagaaatac attacattgc agacaagact tatctaaaac
    11521 tcgaaatcga aaataaatta tcctgctttc aatgcaatgt ctgctttcca acctcattct
    11581 aaacttatga ggaatattga ttttttcacg aataacatca tcaatgattt tatctatcct
    11641 tgaatgaaat cgtaaatttg gattgacaga ataatttaag aaacaatcta acatatattt
    11701 cctgcaatcc gctgtaaaaa tatctgtatt caagcacaaa cagaggtaat ttttctctgt
    11761 gggtgcgtga taaatattta atgtgtcctt attcaatcac atcttccttt ccttgttgtt
    11821 ctggcatagc ttgtctttct tgtgcaagcc tgccgatagt ttgtaaaaaa tcatgtcctt
    11881 tcgggactaa aggcgtgtaa aattcgctga taacacttgt tcccacatca caatagccac
    11941 gccccttgat acgcttctga aaaaactgct ttttcacatc tgaaccgaac agcataccgt
    12001 agcctaattc gctgatacga ccaagcccca cacggaaatt gaagttatct ctgataccgt
    12061 ccgagaaata ctttgcgtct ggacgctggc aggcaacaat aaggaaataa cctgcttgtc
    12121 gccctaacat aacgattttc tttaactggc taagtaaact cacgctttct ttcgtcccca
    12181 gcatttcaaa aaacgccaca tattcatcaa agataagaaa gcagggtggc agtcccagat
    12241 aggcgtagtt ttcacccgtc ttatagttcg ggtgtcgttt catttcctcg cttcgctgta
    12301 ccatgccctc ataaaaggca ttgacgcaat ctatcatttc ttctttggta tggtagacgt
    12361 ttggcatgac cgttcctaag tccgcaaggt cgctattctt cgggtctaag atgtaaagga
    12421 cagcgttggt atgcagtaag gcttcaatga gcgtcagcag aaaataggtt ttaccgccac
    12481 cagttccacc agcaatcaga gcgtgaggga gtgcgtcata ttcccagaca agatttttca
    12541 tcagctttaa acagccgttt tctgcccgta cttcatcaat ggtaatgcgg tttgctatca
    12601 tatcataaag cagggtatat tcgatatagc cgtcatgcaa agtcttgtcg gtcagctcac
    12661 aatataaacc actttccaac ttatcctcta accgtaaaag ctggtcttga tattttccca
    12721 gcgtgatttc acagcggata tgaagcagtc ccttttccat ttgataataa atcttcggaa
    12781 accagacgat tttttccctt gatctgcttt gcaggtcagt aaaaaaaccg ctgtcttgta
    12841 cggtatcggc ttcataccac ttattttcca gtatcattct tgccagcttt tgacggtgca
    12901 ggagcttctt gaaaccgtcg taacagaagc ggtaataccc aaaagcgacc aatgcacaaa
    12961 caccagtcgc tatccctatg gttatgaagt tgtaagggga aagcgtcaag ccgttctcta
    13021 acaagctgaa atgctcccaa tcggtacaca tgagctgttt catattcagt aacaggagaa
    13081 ccgtcacgaa tataaacaga agcattccta tggaaaagtg gtagacaagg tgcttgtcgc
    13141 tggctctgat acggtgtcct ttgttccaaa tcatacgcat aaatcaatca ctcctttctg
    13201 gggatgaaaa aagcagtcaa tcctaagact aactgctttg tgtgtaggga tataaaattg
    13261 taaaactaag attgcatttc agatatggat ttgaaacccc tcatagctga aaataccatt
    13321 cccttgtttt aatttccctt catttgacaa gttgtgaaaa gctgtctcta tcttgtcaat
    13381 tatagtaact ggaatagata aatgatgatg tcctggcaaa attcgactta tctttaaaga
    13441 ttgaattttt ctaacagact tccaaaattc ttgtgggttt gttgatggat aaaaagcatc
    13501 aaggcaaccg ctatatatca aatcgccgga atacagatat tttctatccg cttcatagaa
    13561 acaacaatgt ccgggagaat gaccgggcgt gtgaataact accaactttc tgttccctaa
    13621 gtcaatacaa tcttcatcat gtaaaatcat ttgcggaacc ccttgaaaaa tctgatattt
    13681 ctctacatta aaatccgagg ggaaatcaca tggattgcac ataatattgt tttttaccac
    13741 ttgcaaaggt atagggaatt tgaccgatag ccattctttt tctgcttcat gaactgcaat
    13801 agaccgaaaa tatttatgtc caccgatatg atcccaatga acatgagtag tgattactgt
    13861 aacgggcagt ttcgtcaatc catcaataac ctctctgatg ttggaaacac ctaaacctgt
    13921 atcaatcaga atggctcttt ttgtcccaca caatagataa caatgtgttt cttcccagtg
    13981 tctgtattcg ctgatgacga atgtatcttg gtctatttgt tcgacggtaa accaactgtc
    14041 catatactat tctcactccc taaaaatttt aatttgtcgc tttcttcata cccatattat
    14101 aacagttccg tatatcctct acaacgaaaa tctattcagc aagtctattt tttcggttgt
    14161 ccctgcggtg catggttttg tggattgcct gcgttctggt tgcctttatt cttcaacaca
    14221 atatcctctg cctttacata ccagtccaca tctgcaccac caaacgtctt tcttgatacc
    14281 gtatcggcta cgggattgac aagctccaca actgcattgt acggaaattc ccttagcggt
    14341 acttctggcg gtacagacac ggggataatt ccaccatgca gactgcactt caaatcatag
    14401 atacgctttt taagctgggt actcggtgtc ccgtcctcat tctgtaagaa cacatcacgc
    14461 accgctgtaa actttaattc tccaaatgtt ttctctttgt caataacaaa cccgtttgat
    14521 aatctcataa attcttcact cctttacttt tcttcaactg ctacaatatc atcagcaact
    14581 aatacataat cggtatgtcc catatccccg attgcgtaac ctctgccgta taacttcgga
    14641 ttgacaagtt ttactttctg ctcatacttg aacttctttt cgccagcctg cacgggaatt
    14701 tctaccacaa cattttcgcc tttctgtacg tcggaataaa ggttatagct tcgtctggct
    14761 aagaccctgc gattattttt atctctttca aagactggct cgctttcgcc tgcaaattca
    14821 agagttccaa aagactgtgc catatctggc acaacatatt tcatttccat attgttttac
    14881 ctcgtttctt tctattttta ataagttttt tgattgtgat ttcttattct ggcggttcgg
    14941 gaagtatcag caatcccacc gatagtaaag gggaaaatca atgcttacgc acccttgact
    15001 atccgtgttc ttgcaggtaa gtagcagaca agccagaata agcaaaagtc tgccgtttga
    15061 cagcttcggc ggagagcgtg attttccttt tctcataccg ttactgcctt atgatttttt
    15121 cattttacgg cgtttgtaaa gatatgttcc agccagtcca ccaacagacg caagcaacat
    15181 cacgataaat gccattacat ttgtactgtc gcccgttttg ggactgtcgc taggtctgtt
    15241 aggcttttct ggtgtcggtg gagtttcggg tttctctggt tcttctggct tttccttaaa
    15301 ggtaatcgtc tgtcccttat cctcaatatc cttatgctcg gtaactttct ttggttcgtc
    15361 tggattgctt aaatcgtaca attcttcaaa agttacaagc tgtttgccgt caagagaagt
    15421 agcgtcaaac gtaaaagcaa cttcgacttt catagtttcg ctgtcagcag taaaagtgta
    15481 atcactttcc acacgctttc cattgataag aagctctgca ttttcttctt tcaacatctg
    15541 ccagcccaca agtttgtatt gtgtaccgac ttctaagccc tctaaagtta cggtatcaat
    15601 gattgttacc tcttttccag cttcaagctc tttgttaccg tctttgtcgg tagcagtcgt
    15661 atgtatcttg ataatacgct ctgtgataag taccgtctgc ccgtcgtcct caatgtcttt
    15721 atgctccgca acttttacgg gttcgtctgg attgctgaaa tcatacaatt cttcaaaggt
    15781 aacaaggttc ttgccaccta aagcagacgc attgaatgta taggaaattt ccactttcat
    15841 ttcttcctcg tcagcgacaa aggtataatc attttctaca cgtttcccgt caatgataag
    15901 ctcggcattt tcttctttta acatctgcca gcctttgagc tgatactttg tacctttttt
    15961 aagcccgtct aatttgactg tatcaacgat tgttacctct tttcctgcaa ggatagtctt
    16021 ttcgccgtct ttgctggtcg ctgtggtatg gatagagatt tctttttcgt attcatcagt
    16081 caaagtccct aagtcaatca caaggttatt tcttgatacc acgatttcaa aaggtgggat
    16141 aagttcaaaa cctttgttgc tgtcagagcg taattcttca atgatgtaag tatcataagg
    16201 caacgcccct ttgctgtcgt ctggttcaga agttccaaac cacacaccgt cctcgctggt
    16261 cttgcctgcg ttggtattgt gcttatggga agcccagtca gcagaagtgg agaattgccc
    16321 gttatcatca gttaccacaa catgactttc gcccgtcgtc ttgcttgtga tcctaaaggg
    16381 aacatcagca agacgcttat gtgtgcctgc accgattttc acgccctcaa tatctccacg
    16441 cttaatctga ttgtagatag aatgggcttc gtcggttaag tccacgattt ttccattttc
    16501 tgtgattaca aaatcaatcg gttttgcacc gtcagttaag taaccgttgg gagcttcact
    16561 ttcaacgata cggaattttc cataaggcaa gaggtcagca gaagtagaag cgataccctc
    16621 aatatctgta cgaattgtct ttaccacttc atttttcttg tatagcttgc cctcaaccaa
    16681 gacagaatta tcatttaagg aaatgatgtc aaaagcagta tctttcaaag tggcacttcc
    16741 ttgtggcttc gtatcgcccg tttctaaatc tcgtttctga attttcacac cgccacggat
    16801 aaccttgtct gatacagaaa actggttact tccagatagt acggcaaggt cgccgtcccc
    16861 ggtaatctgt gttacatata agcccttaat ctgttcggac ttatcgccag tctgcatata
    16921 tgcaccgtct aacaagtagc cgtttggagc tttcgtttcc tctacggtta gtgttcctaa
    16981 aggaagaacg gctttaccat cctgcatata gaaactgtcg ccagatacct tgtatgcgtc
    17041 cgctaatttt gtgatgtagt gggttatccc gtcgctgtca gtttcagcga ttgtctttgt
    17101 aacccatgta cgagtagctt cggcagggag attgtctttg ttatagaagc cagcataata
    17161 cttccatgta aattccgcac ctgctagaga agcgttcccc tgcggattgt ctttctgtgt
    17221 ttccatgtca atcttgaaaa gctcaatcaa agtgtccgtt acttttggcg tatctgatac
    17281 ttttaaggtt gctgtttcgc cagctttgat tgtcaatgga tagacagttt tatccacatt
    17341 atatcctgct ggtgcggata attccttgat atagactgtg ccagccgtta cctctataac
    17401 atctgtattt ccattttcat cagtcgtaag ggtggcaagc tgttttgtgc agtccttatc
    17461 agaaaagaca ccgtatgttg caccagcgat tgagtaattc ccgttaccgt ctgtaatgct
    17521 ggtattactg gaaacctttt gcagttttgc atttccgaca tttaatttcg cccagaattg
    17581 ccccaattcc tgcccctcgc cagagtagat ataaccgcca catttatagc gtcctttatt
    17641 ctctttgaca aaggcttttg ccccagcgaa aacctcgtcc tgcgtagcct ttggaatttc
    17701 atcataagaa gctcgcacgt tatcacattg ccagccaaga tgtacgctca atctctgcca
    17761 gacgacacat tgttccaaca gataaacttg tttataattc aattccttgt gagcttcgcc
    17821 atactgtttg acatattcta aggataacgc cacatctgaa atctggtcgg cactcatacg
    17881 ggtgcttgcg tcagttctgg tcttgtaacc gttcttaaaa tctgtattga tgtcaataca
    17941 ataggcagtt tcgccctcga ctttcatata gccctcattg aatgtcgaac cgatagaacc
    18001 gtcattcatt actttttcaa tgataccgac acgctccgca ctttccgtcc agtattgctt
    18061 gctttctgca tggacgggtg tactcggtaa agcagtaacg acagttgcaa gagctaagaa
    18121 gcccgtacac aatcgcttta atatcttttt cataagtcta atgctccttt cgttttgagt
    18181 aataaaatag ccgtccaata agaacggctg gaaatagaaa aggaacgtca tgttaggcgt
    18241 tccatagtct atgaaatatt aaatttttct tgtttcaata ctgatgtgct gtaccatatc
    18301 tttgcatatc taagaaaact agcgtatcaa ggctcattcg ttagtagtaa ataagtagta
    18361 aattgatgtg tttgtttcct tgaaaatgct gatagatact gtgttttagc ggataatcag
    18421 atttttattg tgttttttga ataaaaaaga atcttatttg ttttttatac aattcaatag
    18481 ggtaaaataa aaattaataa attagacaat aaaaaagaat cta
//
LOCUS       DAEPUT010000080        18456 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.082, whole genome shotgun sequence.
ACCESSION   DAEPUT010000080 DAEPUT010000000
VERSION     DAEPUT010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18456
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.082"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..141
                     /locus_tag="KRL22_002985"
     CDS             <1..141
                     /locus_tag="KRL22_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006859297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBH1273436.1"
                     /translation="QLVRAMRLTPQELNAMLSGGGIPGMNAAHATEAADYEEQEENAD
                     EE"
     gene            131..859
                     /locus_tag="KRL22_002986"
     CDS             131..859
                     /locus_tag="KRL22_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBH1273437.1"
                     /translation="MKNKLKKTMTALCAALILMGGFSVPAYAQGAATEPPAGDATNDS
                     NVVVEEKEETPPLTPKGNATLVDDFGGNKQLITVTTKSGNYFYILIDRAAEGEQTVHF
                     LNQVDEADLMALTENGEAAKKPEICNCTEKCEAGKVNTSCPVCVTSMTSCTGKEPTPT
                     PTEQPEEPKEKGGNPGVVLALVLFALLGGGAAFYYFKFMKPKQNVKGDTDLEDFEFED
                     YDEDEPEADTGETSEDEETEEETL"
     gene            1136..1465
                     /locus_tag="KRL22_002987"
     CDS             1136..1465
                     /locus_tag="KRL22_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBH1273438.1"
                     /translation="MNFVSSRKLTWIICSIGILLAVVGVFFLPEIIPVHFANGIADDF
                     GNKVEIFLFPILLLIITLLTGKENIKYFLTHSKTFLTDMQYNLMIDGVLGIILIVEVY
                     VIYASFV"
     gene            1598..3688
                     /locus_tag="KRL22_002988"
     CDS             1598..3688
                     /locus_tag="KRL22_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBH1273439.1"
                     /translation="MILVIAEKPSVAQTIAAVLGAKEKKDGFLTGSGYIVSWCVGHLV
                     GLAEAAAYGEQYKKWNYDSLPILPQEWKYTVASDKEKQFKTLKELMHRAEVSEVVNAC
                     DAGREGELIFRFVYEMADCKKPMRRLWISSMEDSAIKEGFSRLKNGEEYDALFASALC
                     RAKADWLIGINATRLFSVLYNHTLNVGRVQTPTLKMLVDRDAAITTFKKEKYYHVRLA
                     LSGAEAASERISDKAEADALKTTCEASKAVCTSLVKEKKTAAPPKLFDLTSLQREANR
                     LFGYTAKQTLDLAQALYEKRLLTYPRTDSAFLTDDMSDTAAGIIKLLCGKFSFIAGKD
                     FTPELGKVLNSKKVSDHHAIIPTMELAKTDLAALPESERNILTLAGARLLMATAAPHT
                     FEVVTAVFECDGQSFTARGKTILCEGWKEIDRKYRAALKNKPETDDADSDTENTLPQF
                     TEGQTFENPAATVTEHDTTPPKPHNEASLLSSMERAGSEDTDPDAERKGLGTPATRAA
                     VIEKLVKGGFVERKGKQLLPTKDGINLVCVLPDTLTSPQLTAEWENNLTQIAKGKADP
                     TAFMEGIEDMARELVKTYPFLSGDKAQMFKPEREALGSCPRCGSPVYEGKKNYYCSNK
                     ECIFTMWKNDRFFEERKVAFTPKIAAALLQSGKVNVKKLYSPKTGKTYDGTILLADTG
                     GKYVNYRIELPKKK"
     gene            3819..7847
                     /locus_tag="KRL22_002989"
     CDS             3819..7847
                     /locus_tag="KRL22_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1273440.1"
                     /translation="MASLRDTVKNYQEELRDGIAWVAFWKTGRSWNAEYFHLEMSDYL
                     YPEDRSRMEEIKQADPAAVVVNGYYSGYLGEDMNLDELTAGVRRHYENGYSNIGEFIE
                     AHDDRLPPELIEEARAAAHAAGLPFSEKAYRDGEEPDPYLFDGSMSMEDYELMHRMIE
                     KERSEHMEQPILSGYLSNLGKYTEGRPAGEWVSFPTTAEHLKEVFDRIGIDGKNYGEL
                     HITEYQSSIAGLAEKLTELENLDELNYLSELLKMQFDDDREKFVAAMEYGDHTRDLQD
                     IINLAQNLDCYWLYPSVQSAEDYGHYLIEELDELELPEEAKKYFMYEEYGRDAAINDG
                     GSFTEQGYIYNNRNTFTEWYDGRDVPEEYRVTPQPPVQEKEQADLDASAAIPTTATEQ
                     PPVLPIILSSEKPADKMKEITDRLEQGILGLYESDRYAYYLRTMSKFHDYSLNNTILI
                     AMQGGNLVKGYKQWEKEFDRHVKPGEKAIKILAPSPFTVKKQVEKIDPDTQKPVFDKD
                     GKPVTEEKEIKIPAFRVVSVFDISQTEGKELPALTYELTGNVEQYKDFFAALEKTSPF
                     AMGFEALSGGVKGRCNYEEKRIIINEGMDELQNIKTAIHEIAHATLHDTALAMPERPD
                     RRTREVQAESVAYAVCQHYGLDTSDYSFGYIAGWSSGKELAELKGSLETIRSTAASLI
                     DTIDGHFAEIQKAQDKEQTTEQTQPTQETAKQPEAEVAAPELPEETAPVQEKEAQPEQ
                     AAPAAPYYTINEAAAKRAKDMNSFSDYKQGSATAEYRHYVDEAVQLAEKQKQRVDPMY
                     HEKIDSLLDTYARKLAANMNKGYEIDARVPSILIAGGSNFPTRKKEKQNAARDSNYRE
                     WQEIQGLLDKIRSTGMGGISADDPQVVQKLERKLESLEKSQETMKAVNAYYRKHKTLD
                     GCPHLPPEELEKLKADMASSWHLEDKPFATWALSNNSAEIRRVKDRIKSLSQQKEIGF
                     VGWEFDGGKVEANTEANRLQIFFEDKPDEATREALKSNGFRWSPKAGAWQRQLTSNAY
                     YAADYVKAIAPLTGEKPTELQRAHIRQQKVAAQKQPVQEQPEQKAPQSKDTFSIYQIK
                     GGDETRDLRFEPYDRLTATGHRVDPKNYALVYSAELTPGTSLEDIYTRFNIDHPKDFK
                     GHSLSVSDVVVLHQNGQDTAHYVDSFGYKDVPEFFKEQEKALIPDDLETGETIKTPRG
                     TFYVTAMSREQMEAAGYGLHHQSDDGKYLIMGNGTRAFAVPVQPENYLKAAEQTTEQN
                     YNMIDGQINNTPTTAELEAKVKAGETISLVDLAEAVKADKERGKAVKTEKKPSIRAQL
                     RADKEKTAQKKAAKSKNHELEV"
     gene            7850..8056
                     /locus_tag="KRL22_002990"
     CDS             7850..8056
                     /locus_tag="KRL22_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBH1273441.1"
                     /translation="MIRLTVEETNLLSIYNEGGKRGLMENINAALPFMDEDMRELAKR
                     TLAKIAPLTENEYVELAIFAADEV"
     gene            8053..8418
                     /locus_tag="KRL22_002991"
     CDS             8053..8418
                     /locus_tag="KRL22_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBH1273442.1"
                     /translation="MTGVKRLTPPQSRKVNSLVKKECCNCDNGHCILLDDGEECVCPQ
                     LISYSLLCKWFQTAVLPLDKLLYAELFKTEDKKRCTECGTSFASTSNSVKYCPDCRKR
                     ITRRQAAERMRKRRALVTQ"
     gene            complement(8597..8848)
                     /locus_tag="KRL22_002992"
     CDS             complement(8597..8848)
                     /locus_tag="KRL22_002992"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273443.1"
                     /translation="MKIVDITTCIKITEENDMYGIERYLDIGSKIKITFNSGNTLTGY
                     VQYLDYGHYPGENVLLVLKTDEDTLLGAMVCFISNIEVL"
     gene            complement(8851..10197)
                     /locus_tag="KRL22_002993"
     CDS             complement(8851..10197)
                     /locus_tag="KRL22_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBH1273444.1"
                     /translation="MAVTKIKPIKSTLSKALDYIQNPDKTDGKMLVSSFGCSYETADI
                     EFGFTLAQAIEKGNNLAHHLIQSFEPGEVDYEKAHEIGKQLADAVTKGQHEYVLTTHI
                     DKGHIHNHIIFCAVNFVDYHKYNSNKRSYYGIRNMSDKLCRENGLSVVVPGKGSKGKS
                     YAEYQAEKVGTSWKGKLKIAVDTLIPQVASFEELLQRLKAAGYEIKPGKYISCRAPGQ
                     ERFTRLKTLGADYTEEAIKERIAGKRTKAAKAPKEQRGVSLLIDIENSIKAAQSRGYE
                     QWAKIHNLKLAAKTMNFLTEHKIEQYADLVSRIEEINAENEKTADALKSVEKRLADMA
                     VLMKHVTTYQKTKPIYEAYRRATDKDAYRAKQESSLILHEAAVKALKAAGVTKLPNLA
                     AMQEEYGKLQAQKEALYADYGKLKKQVKEYDVIKQNIDSILRQGKEPEREKGKERE"
     gene            complement(10158..10487)
                     /gene="mobC"
                     /locus_tag="KRL22_002994"
     CDS             complement(10158..10487)
                     /gene="mobC"
                     /locus_tag="KRL22_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBH1273445.1"
                     /translation="MNGRKRKIQIKFYVTEEERALIEQKMKLVPTRNMAAYLRKIAID
                     GYIIQTDHSDIKAMTAEIQKIGVNINQIARRVNATGSVYQEDIEEIKGVLAEIWRLQR
                     LSLLKAR"
     gene            complement(10731..11090)
                     /locus_tag="KRL22_002995"
     CDS             complement(10731..11090)
                     /locus_tag="KRL22_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273446.1"
                     /translation="MKQSKEKFDFKAFGQAIKAARKAKGISRNQLADTLNIAPRYIAS
                     IENSGQHPSLQILYELVTLLDVSVDQFFFPEREQEKSTRRRQLDTMLDTMSETDLKIM
                     SATAKGIEEANNDRTGE"
     gene            11266..11460
                     /locus_tag="KRL22_002996"
     CDS             11266..11460
                     /locus_tag="KRL22_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018596008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1273447.1"
                     /translation="MEYISCMEAAENWGISERRVQKLCEENRIPGATKFSRIWLIPKK
                     AEKPIDRRKQHAADTTNSNR"
     gene            11429..12118
                     /locus_tag="KRL22_002997"
     CDS             11429..12118
                     /locus_tag="KRL22_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008982483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1273448.1"
                     /translation="MQQILQILIVEDDILLSDMLKSLLSQNGYRVNTAYSGSEALLIL
                     EKETFDLILLDLMLPGISGEEVLTTIRKKQTTPIIGVSAKTDIDSRIDLIKNGADDYI
                     TKPFDNKELLVRMEAILRRCHRSSNNSLLKFKDLMLNPATMEVTIKDIPLVLTRYEYL
                     ILQLLMTAPNKVFTKNNIFESVWNETFCGDDNAINVHISNLRKKFAKINPNEQYIQTV
                     WGLGFKMQSNP"
     gene            12150..13076
                     /locus_tag="KRL22_002998"
     CDS             12150..13076
                     /locus_tag="KRL22_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005930880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273449.1"
                     /translation="MHNTYTIIERGGSVGLVLEVKNLSYVFPNGVGIIGIDFQIDYND
                     IYYLYGSHNSGKSLILQSILGIISPQKGSIKIFENPDFLQEKRRIGYVPQSPYYIDRM
                     TITDMMNYFSLSFGVLEKNFADILNLNLKEKKPVRHLSSFIQRKLNLWIALLGNPDLV
                     FIDDPFGGLDTQESEQLISIISYLNKNNNITFLLTGHNYELASRIATKYGVLKNGRFL
                     IELTPEKLDSECKRCIKIRTPQLLSAIPLLEKEFPQYEVLEDDLIRVFCPLSHSAKIN
                     TLLVSAGIEVSEIWIAGTMPQEYLLKLTEGGI"
     gene            13080..13856
                     /locus_tag="KRL22_002999"
     CDS             13080..13856
                     /locus_tag="KRL22_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273450.1"
                     /translation="MIKMIQGELFRIRKNRLFKICLIVSTFFVFALALTFHYNTIKHS
                     VAAVPKASLNDYTQFLFSDYSLILPITVFLGCYFTENSRTGTCSIFLSKGITRTSIFF
                     GKLISSWIATVLYMLFNFLMAYIFILVMWVKQSYIDCSFGLIGIYLFLQILCFIGYTS
                     FIWLLSILFRYRSLVITISIFLLGTLYFYLTKISSALDLSYSLYRYWIAGLSHAMEIR
                     LVLPQLPLILLTITGYVFFPTLCSFVIYKKIDLRKHERDK"
     gene            13858..14754
                     /locus_tag="KRL22_003000"
     CDS             13858..14754
                     /locus_tag="KRL22_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004064258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1273451.1"
                     /translation="MSIFCIFLVVTSLILLLKVIIQKQQITKIKNQIDFLCSRDTQAE
                     ITLEKLDKQTEELAISINHLLKKYRLTGIKIERNDSLFRDTITSLSHDLRTPLATANG
                     YIQLLLEQPLSAEQKEYVKIANERVSAVKILLDQLFEFARIEANELKLNKQLVDANSV
                     LRDALATYYNDFEIKAITPTIDIPDSPAMIWADKDALFRVFSNIIYNALIHGDSVYTI
                     HATVERKCYYISISNHSNTICKEDIPHLFDRFYTTDSSRTKKTTGLGLAIARKLITQM
                     GGEISAHLHNEIFEICISFTIL"
     gene            14864..15040
                     /locus_tag="KRL22_003001"
     CDS             14864..15040
                     /locus_tag="KRL22_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005341180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="receptor"
                     /protein_id="HBH1273452.1"
                     /translation="MLSKISLIISIVALAVCFIAAISGILSDGMKGLQKKGKLLGVTF
                     CIYAITFLTFIISQ"
     gene            15053..15745
                     /locus_tag="KRL22_003002"
     CDS             15053..15745
                     /locus_tag="KRL22_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008982479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1273453.1"
                     /translation="MLQIKNVNLCVGSNKLLHNINLSLEQGKIYGLLGANGAGKTTLF
                     KSMLGLTAYTGEILSDKNPAKSSEFGSLIEYPAFYPKLSVMENLKLHASYIGLTNPDI
                     ENSLKQVNLWEARNKLFSQLSLGMRQRLGIARTFLGNAKYLLLDEPTNGLDPMGIKDI
                     RILLRDKLKTPKHCIIVSSHNLTEIAAIADILIFIRNGQIIEMIENKYDEKELEVLYE
                     NLMTSITTEEVQ"
     gene            15742..16497
                     /locus_tag="KRL22_003003"
     CDS             15742..16497
                     /locus_tag="KRL22_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273454.1"
                     /translation="MKVLIKNEFTKLKREWFVLFLLLLSWLPVLTGGVGAVFNNSTKT
                     VSDLFFFMNNQFSMFFPMVIVILTGSLFYQEYKNKTYINWITYGYSKQQLFSAKIIVG
                     FVIEIVFAASLICLFHILILMLKIAGKVSVDIQEILSLTVGFALEAIIVILITTCIAA
                     IIINISRNIIVTSVIGVIYGFVSCFFIGSEFGYVIPGSFAYRLSMYFSDSSTYYELAK
                     QATIGGCISSIISFGLMLFMGIFIFTRKKKIES"
     gene            16961..17401
                     /locus_tag="KRL22_003004"
     CDS             16961..17401
                     /locus_tag="KRL22_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016283905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1273455.1"
                     /translation="MTPNRREFEKQCAFQKFCKSVLHNEACNAHEEIRRRRVREVAFS
                     DLALHEERQLYTVDKYFQDEEVEPSYQMAGKEITPKLLLEAIRALPEERRKIVLLYYF
                     EGLTDIEIGKQLNLSRSTVQYRRTSSFEQLKKYLEENADEWIEW"
     gene            17382..17639
                     /locus_tag="KRL22_003005"
     CDS             17382..17639
                     /locus_tag="KRL22_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019727567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273456.1"
                     /translation="MNGLNGNQNDYPENALVPYPVILAASKGDPDAMKIVLQHFSGYI
                     ASLSMRKLYDERGNVYFGVDEEIRERLQAKLMRAILTFRAE"
     gene            18058..18261
                     /locus_tag="KRL22_003006"
     CDS             18058..18261
                     /locus_tag="KRL22_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family DNA-binding protein"
                     /protein_id="HBH1273457.1"
                     /translation="MNNNDVPIWEKYTLTIEEAAKYFRIGESKLRKLAEENPVPDWVM
                     MNGNRIQIKRKQFEKMIDTVDAI"
     gene            18341..>18456
                     /locus_tag="KRL22_003007"
     CDS             18341..>18456
                     /locus_tag="KRL22_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005343085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH1273458.1"
                     /translation="MSEKRRDNKNRILRTGESQRKDGRYAYKYIDTFGKPQFV"
BASE COUNT         5537 a         3953 c         4060 g         4906 t
ORIGIN      
        1 cagcttgtac gagctatgcg tctgaccccg caggaactta acgctatgct gtccggcggc
       61 ggtattcccg gcatgaacgc cgcacacgct accgaagcgg cagactacga agaacaggag
      121 gaaaatgcag atgaagaata aactgaaaaa gaccatgact gccctttgtg ccgcccttat
      181 ccttatgggc ggtttttctg tccctgccta tgcacagggc gcagccacag agccgcccgc
      241 aggggacgcg accaacgaca gcaacgtagt tgtggaggaa aaagaggaaa cgccgcccct
      301 taccccaaag ggaaacgcta cactggttga cgatttcggc ggcaataagc agcttatcac
      361 tgttaccacc aaaagcggca actatttcta tatcctcatt gaccgcgccg ccgagggcga
      421 acagaccgta catttcctaa atcaagtgga cgaagccgac cttatggcac tgaccgaaaa
      481 cggcgaagct gccaaaaagc cggaaatctg taactgtacg gaaaaatgcg aagccggaaa
      541 ggtaaacacg tcctgcccgg tatgtgttac cagtatgaca agctgcacag gcaaagaacc
      601 caccccaacc ccaaccgagc agccggaaga accgaaagaa aaaggcggca atcccggtgt
      661 ggtgcttgcc ttagtcctct ttgccctgct tggtggcggc gcagcgttct actactttaa
      721 gtttatgaag ccgaagcaga atgtaaaggg cgataccgac cttgaagatt ttgaatttga
      781 ggactacgac gaggacgagc cggaagcaga taccggggaa acttccgaag atgaagaaac
      841 ggaggaagaa accctatgac cctgtttacc gacaatccct ttgaaaagat gatgatacag
      901 aaaccgaacg ggcggcgtga taatgcgccg cctgttcctt atcccccggc ttgcgcttcc
      961 tgcccttata agggacagtc cccttgtgtg gggtactgta tcagaaagat tgaaaccaaa
     1021 caaccgacag aacgataaaa agatatactt acgatatgaa atgtgatata attttccgca
     1081 aatagaaaat agcaatgcta aacaaatcta aatttgatag aaagaaggaa tttttatgaa
     1141 ttttgtaagt agtagaaaat taacatggat aatttgcagt attggtattt tattagcggt
     1201 agtaggtgtg tttttcttac cagagattat tcctgttcat tttgcaaatg gaatagcaga
     1261 tgattttggc aataaggtag agattttttt atttcctatt ttgttattga taattacact
     1321 tttaactgga aaagaaaaca ttaaatactt cttgacacat tcaaaaacat tcttgacaga
     1381 tatgcagtat aatttgatga ttgatggcgt tcttgggatt attttgattg tagaggtata
     1441 tgttatctat gcttcatttg tttaaacata tcgaagatag actctgactt tttcatacaa
     1501 tttattattt tcatatcgca caattttata caatcacttg gaggagcaat cgaaaaatcg
     1561 gttgctcttt tcttttaccc gaaaggagga tttatcattg attttagtta tcgcagaaaa
     1621 gcccagtgtg gcgcagacaa tcgctgccgt acttggggca aaggaaaaga aagacggatt
     1681 tctcacagga agcggctata tcgtttcttg gtgcgtggga catttggtag ggcttgcgga
     1741 agctgccgcc tacggggaac aatataaaaa gtggaactat gacagcttac cgattttgcc
     1801 gcaggaatgg aagtacaccg tcgcttctga caaggaaaag caattcaaaa ccctaaaaga
     1861 gcttatgcac cgggcagaag tttccgaagt cgtcaatgcc tgcgacgcag ggcgcgaggg
     1921 agaactcatt ttccgttttg tctatgaaat ggcggactgc aagaaaccta tgcgccgcct
     1981 ttggatttct tctatggagg acagcgcaat caaagagggc ttttcccgtc tgaagaacgg
     2041 cgaggaatac gacgcgctct ttgcttccgc attatgcagg gcaaaggcag actggctaat
     2101 cggtatcaat gccacccgtc ttttctctgt cctttacaat cataccttga acgtgggacg
     2161 cgtacagacc ccgaccttaa aaatgcttgt tgaccgggac gcagcgatta ccacattcaa
     2221 gaaagaaaaa tactaccatg tgcgccttgc cttatccggc gcggaagctg caagtgaacg
     2281 aatttcagat aaggcagaag ccgacgcatt aaaaacgact tgtgaagcgt caaaagcagt
     2341 ctgtacttcc cttgtgaaag agaaaaagac cgcagccccg ccgaagctct ttgaccttac
     2401 ttctttacag agggaagcaa accgcctgtt cggatatacc gcaaagcaga cccttgacct
     2461 tgcacaagcc ctgtatgaaa aaagacttct tacttatccg agaacagaca gcgcatttct
     2521 gaccgacgac atgagcgaca cagcggcggg cattatcaag ctgctttgcg gaaagttttc
     2581 ttttatagcg ggaaaagact tcacgccgga gcttggaaag gtgctgaaca gtaaaaaggt
     2641 atcagaccac catgccatta tcccgactat ggagcttgca aagaccgacc ttgccgcgct
     2701 gccggaaagc gaaaggaata tccttaccct tgccggggcg cgtctgctca tggcgaccgc
     2761 tgcaccgcat acctttgaag tggttacagc agtttttgaa tgtgacggac agtcctttac
     2821 cgcaaggggc aagaccattc tttgtgaggg ttggaaagag attgaccgaa aatacagggc
     2881 agccttaaag aacaagcccg aaacggacga cgcagacagc gacacagaaa ataccctgcc
     2941 acagtttacc gagggacaga cctttgaaaa tccggcggca acggtaacgg agcatgacac
     3001 aacaccgcca aagccccaca acgaagcgtc gctcctttct tctatggagc gcgccggaag
     3061 cgaggacacc gacccggacg ccgaacgcaa agggcttgga actcccgcca cccgcgccgc
     3121 cgtcattgaa aaactggtaa agggcggctt tgtggagcga aaaggcaagc agctacttcc
     3181 cacaaaagac ggtatcaacc ttgtgtgcgt cctgccggac accttgacaa gcccgcagct
     3241 taccgcagaa tgggaaaaca atctgacgca gattgcaaaa ggcaaggcag accccaccgc
     3301 atttatggag ggtatcgagg atatggcgcg ggaactggta aagacctatc cgtttctttc
     3361 tggtgataaa gcgcagatgt tcaagccgga acgggaagca ttgggaagct gcccccgctg
     3421 cggctctcct gtctatgagg gaaagaaaaa ctactattgc agcaataaag aatgtatctt
     3481 taccatgtgg aaaaatgacc gtttttttga ggaacgcaaa gtagccttta cccccaaaat
     3541 tgccgcggca ctcttacaat ccggcaaggt aaatgtgaaa aagctctatt ccccaaagac
     3601 gggcaaaacc tacgacggaa ctatcttatt ggctgatacg ggcgggaaat atgtcaacta
     3661 ccgcattgaa ctgccgaaga aaaaataact gaatagcaag cataggaaaa gagtaccctt
     3721 ttccgtaaaa tccctgcttt ctctaccgag aacggcgggg atttttgctt gttgggaagt
     3781 ttcccaaacc ctttaagagc gaagaaagga ggttacacat ggcaagttta cgggacaccg
     3841 taaagaacta tcaagaagaa ttaagggacg gtatcgcttg ggtggcgttt tggaaaacgg
     3901 gacgttcttg gaacgccgaa tatttccacc ttgaaatgag cgactacctt tacccggagg
     3961 acagaagccg catggaagaa atcaaacagg ctgaccccgc cgccgttgtg gtaaacggct
     4021 attattccgg ctatcttggc gaggatatga accttgacga gctgaccgcc ggggtgcgcc
     4081 gccactacga aaacggatat agcaatatcg gggaatttat cgaagcccac gacgacaggc
     4141 tgccgccgga gcttatcgag gaagcaagag ccgccgccca cgctgcgggg cttcctttct
     4201 ctgaaaaagc ctaccgggac ggcgaagaac ccgaccccta tctatttgac ggtagcatga
     4261 gcatggagga ctacgagctt atgcaccgca tgattgagaa agaaaggagc gaacacatgg
     4321 aacaaccgat tttaagcggg tatctttcta atcttggaaa gtacaccgag ggcagacctg
     4381 cgggcgaatg ggtatcattc cccacgactg ccgagcattt gaaagaagtc tttgaccgta
     4441 tcggcataga cggcaaaaac tacggggagc tgcatatcac agaataccag tcctctattg
     4501 cgggactggc agagaaattg accgagcttg aaaaccttga cgagctgaac tatttgagcg
     4561 aacttttgaa aatgcagttt gacgacgacc gggaaaaatt tgttgcagct atggaatacg
     4621 gcgaccatac aagggacttg caggacatta tcaatcttgc acaaaacctt gattgttact
     4681 ggctttatcc gtccgtacag agtgcggaag attacgggca ttatctgatt gaagaactgg
     4741 acgagttgga gctgcccgaa gaagcaaaaa aatatttcat gtatgaggaa tacgggcggg
     4801 acgctgctat caatgacggg ggcagcttta ccgagcaggg ctatatctat aataaccgca
     4861 acacctttac agaatggtac gacgggcgcg acgtgccgga ggaataccgg gtaacgccac
     4921 agccgccagt acaggaaaag gaacaagcag accttgacgc ttccgcagcc ataccgacca
     4981 ccgccacaga gcagcccccg gttctcccga ttatcctatc ttccgaaaag cccgccgata
     5041 aaatgaaaga gattaccgac cgactggaac aagggatttt aggactttat gaaagcgacc
     5101 gttacgccta ttatctgcgt accatgtcta aattccatga ttacagcctt aacaatacaa
     5161 tccttatcgc catgcagggc ggcaaccttg tgaaaggcta taaacaatgg gaaaaggaat
     5221 ttgaccgcca tgtaaagccg ggagaaaaag ctatcaagat acttgcaccg tccccgttta
     5281 ctgttaagaa gcaggtggaa aaaatcgacc cggacaccca aaagcctgtt ttcgataagg
     5341 acggaaagcc tgttaccgaa gaaaaagaaa tcaagatacc cgcctttcgt gtggtatctg
     5401 tctttgatat ttcacagacc gagggaaaag aacttcctgc ccttacctat gagctgacgg
     5461 gcaacgtgga acaatacaag gactttttcg ctgcccttga aaagacttcc ccctttgcta
     5521 tgggatttga agcactaagc ggcggcgtaa agggacgctg caattatgag gaaaagcgta
     5581 tcatcatcaa cgagggtatg gacgaattgc agaatatcaa gaccgcaatc catgaaatcg
     5641 cccacgccac gctgcatgat accgcccttg ccatgccgga acgccccgac cgccgcaccc
     5701 gcgaggtaca ggcggaaagc gtcgcctatg ctgtctgcca acattacggg cttgatacgt
     5761 cggactattc ttttgggtat atcgccgggt ggagcagcgg aaaagaactt gcagaactga
     5821 aaggctctct tgaaacaatc cgcagtaccg ccgcaagtct gattgatacc atagacggac
     5881 attttgcaga aatccaaaag gcacaggata aggaacagac caccgaacag acacagccca
     5941 cacaggaaac cgccaaacag cccgaagcag aagtagccgc gccggagctt cccgaagaaa
     6001 cagccccggt acaggaaaaa gaagcacagc cggaacaggc tgcacccgcc gccccttatt
     6061 acactatcaa tgaagctgcc gccaaacgtg caaaggatat gaacagcttt tccgattata
     6121 agcaaggcag cgcgacggct gaatacaggc attatgttga tgaagccgta cagcttgcag
     6181 aaaagcagaa acagcgggta gacccgatgt accatgagaa aatcgacagc ctgcttgaca
     6241 cctacgcccg gaaactggcg gcgaacatga acaaaggcta tgagattgac gcgcgtgttc
     6301 cctctatcct gattgcgggc ggctctaact ttcccacaag gaagaaagaa aagcagaacg
     6361 cagcccgcga cagcaattac cgggaatggc aggaaataca gggattgctt gataaaatcc
     6421 gcagcaccgg catgggcggt atcagcgcag acgacccaca ggtagtacag aaattagaaa
     6481 ggaaactgga aagccttgaa aaatcacagg aaaccatgaa agccgtaaac gcctattacc
     6541 gcaagcataa gacccttgac ggctgcccgc atttaccgcc ggaggaactg gaaaaactga
     6601 aagcagacat ggcgagcagt tggcatttgg aggacaagcc ctttgcgact tgggcgttat
     6661 ccaacaacag cgcagaaatc cggcgcgtga aagaccgtat caaatccctt tcacagcaaa
     6721 aagaaatcgg ttttgtgggt tgggaatttg acggcggcaa ggtggaagca aacaccgaag
     6781 caaaccgcct gcaaatcttc tttgaagata agccggacga agccacgcgg gaagccctaa
     6841 aaagtaatgg cttccgttgg tcgcccaaag caggggcatg gcagcggcag cttaccagta
     6901 acgcctacta tgcggctgat tatgtcaagg cgattgcacc ccttaccggg gaaaagccta
     6961 ccgagttaca gcgggcgcat atccggcagc aaaaggtagc tgcacagaaa caacccgtac
     7021 aggagcagcc ggaacagaaa gccccacaga gcaaagacac cttttccatt tatcagataa
     7081 aaggcgggga cgaaacaaga gatttgcgct ttgaacctta tgaccgtctg actgccacag
     7141 gacaccgggt agacccaaaa aactatgccc ttgtctattc cgcagagctt acgccgggga
     7201 cttcccttga agatatttac acccgcttta atatcgacca cccgaaagat tttaagggac
     7261 acagcctttc cgtttccgac gtggtggtac ttcatcagaa cgggcaggac accgcccact
     7321 atgtagacag ctttggttat aaggacgtgc cggaattttt caaggaacag gaaaaagccc
     7381 tcattcccga cgacttggaa acgggcgaaa caatcaaaac accgagaggg actttctatg
     7441 taaccgccat gagccgcgag caaatggaag ctgccggata tggattacac caccagtccg
     7501 acgacggaaa atatctgatt atggggaacg gtacaagggc ttttgctgtt cccgttcagc
     7561 cggaaaacta tctgaaagct gccgagcaga ccacagagca aaactacaat atgattgacg
     7621 ggcagataaa caacactccg accaccgcag aactggaagc aaaggtaaag gcaggagaaa
     7681 ccatttccct tgttgacctt gcggaagctg ttaaggctga caaggaacgc ggcaaagcag
     7741 taaaaacgga aaagaagccc tctatccggg cgcagcttag agcagacaaa gaaaaaaccg
     7801 cacagaaaaa agcagcaaaa tcaaaaaatc acgaattgga ggtatgaaca tgattagact
     7861 gaccgttgaa gaaacaaacc tgttgagcat ttacaatgag ggcggcaagc gcgggcttat
     7921 ggagaacatc aacgctgcgc tgccattcat ggacgaggat atgcgggaac ttgcgaaacg
     7981 tacccttgcg aaaatcgcac ctctgacaga aaatgagtat gtggagcttg ccattttcgc
     8041 cgctgatgaa gtatgaccgg ggttaagcgg cttacgccgc cccaaagccg gaaagtcaac
     8101 agccttgtaa aaaaggagtg ctgcaactgc gataacggac actgtatttt actggacgac
     8161 ggggaggaat gtgtctgccc gcagcttatt tcctattcgc ttctttgcaa atggtttcag
     8221 accgccgtat tgccccttga taagctgctg tatgcagagc ttttcaagac cgaggataaa
     8281 aagcgttgta ccgagtgcgg aacctctttt gcgtccacct ctaacagcgt caaatactgc
     8341 ccggactgcc ggaagcgtat tacccgcaga caggcagcgg agcgcatgag aaaacggcgc
     8401 gcccttgtta cgcagtaggg gcaaaaaaag tcttgattta cggggcataa cagatacgaa
     8461 acttgcataa gcgatacgaa ataccttttc ccttaaaatc agggttctac tgcgtaacat
     8521 atcaaatcat ctgcacccac aaaaaacggg cgcggcggct atgattacat ggctgctgcg
     8581 tccgttcttt ttttgtctac aatacttcta tattcgatat gaaacatacc attgcgccga
     8641 gtaatgtatc ttcatctgtt tttaagacga gcaatacatt ctctccggga taatgtccgt
     8701 aatccaaata ctgcacatat cctgtaagtg tgtttccgct gttaaatgtg atttttattt
     8761 tactgcctat atcaagatac ctttctatgc cgtacatatc attttcttct gttattttga
     8821 tacacgttgt aatgtcaaca attttcataa ttattcccgt tccttccctt tctcccgttc
     8881 cggttctttg ccctgccgca aaatgctgtc tatgttctgc ttgataacgt cgtattcctt
     8941 gacctgtttt ttcagctttc cataatcagc gtaaagggct tctttctgcg cttggagctt
     9001 cccgtattct tcctgcatag cggcgagatt ggggagctta gtaacgcccg ccgctttcag
     9061 tgcctttact gccgcttcgt ggagtatcag actgctttcc tgttttgccc ggtatgcgtc
     9121 cttatccgtt gccctgcggt atgcttcata aataggtttt gtcttttggt aggtggtaac
     9181 gtgcttcatc agtactgcca tgtctgcaag acgcttctcc acgctcttta atgcgtctgc
     9241 tgtcttttca ttttccgcat ttatttcctc aatccggctg actaaatctg cgtactgctc
     9301 aatcttatgt tctgtcaaga aattcatggt ctttgctgcc agtttcagat tatggatttt
     9361 cgcccactgt tcatagcccc ggctttgcgc tgccttgata ctgttttcaa tgtcgataag
     9421 cagcgatacg ccgcgttgct ctttgggagc tttcgccgcc tttgtgcgct tgcctgcaat
     9481 ccgttctttg attgcttcct ctgtataatc tgcaccgaga gtttttaagc gggtaaatcg
     9541 ttcctgtccg ggagcgcggc aggagatata ttttcccggt tttatctcat agcccgctgc
     9601 ctttaaccgc tgcaataatt cttcaaaact tgccacttgg gggataagtg tatcaacggc
     9661 aattttcagc ttgcctttcc aacttgtacc gaccttttcc gcttgatatt ctgcatagct
     9721 ttttcccttg ctgcctttgc ccggaacgac aacagacagc ccgttttccc ggcacagctt
     9781 atcactcatg ttccgtatgc catagtagct gcgtttattg gaattgtatt tatggtagtc
     9841 aacgaaattg accgcacaaa aaatgatatg gttatggata tgccccttgt ctatgtgggt
     9901 ggttaggaca tattcatgct gtccctttgt taccgcgtcg gcaagctgtt ttccgatttc
     9961 gtgggctttc tcatagtcta cttctcccgg ctcaaaggac tgtatcaaat ggtgggcgag
    10021 attgttccct ttctctatgg cttgtgcaag cgtaaatccg aactcaatat ctgccgtttc
    10081 atagctgcac ccaaaggagg acacaagcat tttcccgtct gttttatccg ggttttggat
    10141 atagtcaagg gctttgctca acgtgctttt aataggctta atctttgtaa ccgccatatc
    10201 tctgcaagca ccccctttat ttcctctatg tcctcttggt agacgctgcc tgtcgcattg
    10261 acacgccttg caatctgatt gatgttgacc ccgattttct gtatctccgc tgtcatggct
    10321 tttatgtcgc tatggtctgt ctgaatgata tacccgtcaa tggcaatctt gcgaagatac
    10381 gccgccatgt tccgggtggg aacgagcttc attttctgct caatcaatgc ccgttcttcc
    10441 tctgttacat agaatttgat ttgtattttt cttttgcgtc cgttcatgca atcgctcctt
    10501 tccattccga gggtttggga cacttcccaa caagcaattt tcaaccgacg caccgcagga
    10561 cgggagggcg aaaatacgga aaagggtact cttttcctat gcttgctaag aaagtttttt
    10621 cctcacttat cactacaacg aaactcccag tatgccaaaa aagagcaaaa gaaaaacgcc
    10681 gcaatcctgc gacgtttcaa tcactttatg cagacaaaaa cgagggaact ttattccccc
    10741 gtcctgtcgt tgttggcttc ctctatgcct tttgcagtag cagacatgat ttttaagtct
    10801 gtttcgctca ttgtgtcaag catggtatcg agctgacggc ggcgtgtgga cttctcctgt
    10861 tctcgttccg ggaaaaagaa ctggtctact gatacgtcaa gcaaagtcac aagctcatac
    10921 aaaatctgta aacttgggtg ctgcccgctg ttctcaatgg acgcgatata tcggggcgca
    10981 atattcagcg tgtcggctaa ctgattgcgt gatattccct ttgcttttct tgctgcttta
    11041 atggcttgtc cgaaagcctt aaaatcaaat ttctctttac tctgcttcat aattatttca
    11101 cccagttaca ttttactgtt cctcttttct ttgagatatg attacacata tcgtagtatt
    11161 gactaaaata gagcatatta tttatgcgcc acttcttgta tttgttcggt tgaacgtata
    11221 taataatatt ggcgaagtta atttctgatg aaagggtgtc aaaatatgga gtatatatct
    11281 tgcatggaag ccgcagaaaa ttggggaatt tctgaaagac gagtacaaaa gttgtgtgaa
    11341 gaaaacagaa tacccggagc gactaaattc agccgtatat ggctgatacc aaaaaaagca
    11401 gaaaaaccga ttgacaggag gaaacagcat gcagcagata ctacaaattc taatcgttga
    11461 agatgatatt ttactaagtg atatgctaaa aagtctatta tctcaaaacg gatatagagt
    11521 taatacagct tattcgggga gtgaagcact tttaatcctt gaaaaagaaa cttttgattt
    11581 aattttactt gatttaatgc tgccgggaat atctggcgaa gaagtattga caacaataag
    11641 aaaaaaacaa actacgccga ttattggtgt gtctgcaaaa acggatattg acagtagaat
    11701 tgatttgata aaaaacggtg ctgatgatta tattacgaag ccttttgata ataaagaact
    11761 gttagtgcga atggaagcta ttttacgtcg ctgtcataga agcagcaata actccctatt
    11821 aaaatttaag gacttaatgc ttaatccggc aacaatggaa gtgacaataa aagatattcc
    11881 ccttgttctc acaagatatg aatatttaat tttacagtta ttgatgactg cccctaataa
    11941 ggtctttacc aaaaataata tctttgaaag tgtatggaat gaaacttttt gcggagatga
    12001 taatgcaatc aatgtccaca taagcaatct tcggaaaaaa tttgctaaga taaatccgaa
    12061 tgagcagtat atacagacag tatggggatt gggctttaaa atgcagagta atccttagaa
    12121 aatgcttata aataaagcta taatctttaa ttcacaatac atatacgata atagaaagag
    12181 gtggaagtgt ggggcttgtt ttagaagtga aaaatttatc ctatgttttc ccaaatggcg
    12241 ttggtattat tggcatagac tttcaaatag attataacga tatttattat ttatatggaa
    12301 gtcataactc cggcaaaagt ttaatattac aatcaatact tggtataatt tctccacaaa
    12361 agggaagcat taaaattttt gaaaatcccg attttttaca agagaaaagg cgtattggat
    12421 atgtaccaca aagtccatat tacattgaca gaatgactat aacagatatg atgaattatt
    12481 tttctttatc atttggggta ttagaaaaaa actttgcaga tatattaaac cttaatctga
    12541 aagaaaagaa acctgttcgt catttatctt cctttatcca acgaaaacta aatttgtgga
    12601 ttgctctttt gggaaatcct gatttggttt ttatagacga cccatttgga ggactcgata
    12661 ctcaagaaag tgaacaactt atttcaatca tatcttatct gaataagaat aataatatca
    12721 cttttttgtt gacaggacat aattatgagc ttgcttcccg aattgcaaca aaatatggag
    12781 ttcttaaaaa tgggcgtttc ttaatagaac tcactccaga aaaattagac agtgagtgca
    12841 aacgctgtat caaaataaga acgccacaat tactttctgc aattccttta ttagaaaaag
    12901 agttcccgca atatgaggtt ttagaagatg atttaatcag agtattttgc cccttatctc
    12961 attctgctaa gataaataca ttattagtat ccgccggaat agaggtatca gaaatttgga
    13021 ttgctggaac tatgccacaa gaatatcttc taaaattaac ggaaggagga atatagccta
    13081 tgattaaaat gatacaagga gagctttttc gtattcgcaa aaatcgttta tttaagatat
    13141 gtttgatagt atccacattt tttgtttttg cacttgcatt gacttttcat tacaatacaa
    13201 taaagcactc cgttgcggct gttccgaaag cgtccttaaa cgattatacg caatttttgt
    13261 tttcagatta tagtttaata cttcctatta cggtattctt gggctgctac ttcacagaaa
    13321 acagccggac tggtacttgt tcgattttct tgtcaaaagg aattacaaga acatcaattt
    13381 tttttggtaa actaatttct tcatggattg ccactgtcct gtatatgctg ttcaattttc
    13441 ttatggcata tatttttatc ttagttatgt gggtaaaaca atcctacatt gattgctcgt
    13501 ttgggctaat cggtatctac ctgtttttac agattttatg ctttataggc tatacttctt
    13561 ttatttggct actaagtatc ttatttcgtt atcgtagcct tgttatcaca atttctattt
    13621 ttttattggg gacattatac ttctatctta caaaaataag ttcagcctta gacttatcct
    13681 attcactata tcgttattgg atagcagggt tatctcatgc aatggaaatc agattagtac
    13741 tgccacaatt accgctcata ttgcttacca ttaccggata tgtgtttttc cctacattat
    13801 gttcattcgt tatttacaaa aaaatagatt tgcgcaagca cgaaagggat aaataatatg
    13861 agtatatttt gtatttttct tgtagttaca tctttgatat tactattaaa agtaattatt
    13921 caaaagcaac aaataactaa aatcaaaaat caaatagact ttttatgttc cagagataca
    13981 caagcagaaa taaccttaga aaaactggat aaacagacag aagaacttgc tattagtatc
    14041 aatcatcttt tgaaaaaata tagattgacc gggataaaaa ttgaacgaaa tgacagttta
    14101 tttcgtgata caatcacaag cctttcccac gatttgcgta ccccgctcgc aactgcgaat
    14161 ggctatatac aactactttt agaacaacct ctatccgctg aacagaaaga atatgtaaaa
    14221 atagcaaatg agcgagtttc ggcagtaaag atattgcttg accagctttt tgaatttgcg
    14281 agaattgaag cgaatgaact aaaactaaat aaacagttag tagatgccaa cagtgtttta
    14341 agagatgcct tagcaacata ctataatgac tttgaaataa aagctattac ccctactatt
    14401 gatattcccg atagtccggc tatgatttgg gcagacaaag acgcattatt tagggttttc
    14461 tcaaatatca tatataacgc tttaatacat ggcgatagtg tttatacaat ccatgcaaca
    14521 gttgaaagaa agtgttatta tatcagtatt tccaaccatt caaatacaat ctgtaaagag
    14581 gatatacctc atctgtttga ccgtttctat acaacagaca gttctcgtac aaaaaaaaca
    14641 acgggactgg ggttagcaat cgcgcgtaaa ctgattacac aaatgggtgg agaaatatct
    14701 gcacatttac acaatgaaat atttgaaata tgtatttcct ttacaatttt ataaaaacag
    14761 ggtggctatg gctaccctgt ttttatcttt agacttttct tagacttttc ctaaaaaaat
    14821 cataactctc tttgttacta tacattacaa gggaggtggt caaatgttat ctaaaatttc
    14881 cttaatcatt tcgattgttg cacttgctgt atgttttatt gcagcaatca gtggtatttt
    14941 aagcgacggt atgaaaggct tgcaaaaaaa aggaaaacta cttggtgtta cattttgtat
    15001 ttatgcaata acttttttga cttttataat ctcacaataa tggaggtcta caatgttaca
    15061 aattaaaaat gtaaatcttt gtgtcggaag caacaagcta cttcacaata tcaatctttc
    15121 tttagaacaa ggaaagatat atggactact tggtgcaaat ggcgcaggca aaaccacatt
    15181 gtttaagtct atgttaggac tgactgctta tacaggcgaa attctttcag ataaaaatcc
    15241 cgctaaaagt agtgagtttg gaagtttaat tgaatatcct gcattttacc caaaactttc
    15301 cgtcatggaa aatctgaaac ttcatgcaag ttatattggg cttacaaatc ccgacataga
    15361 aaattctttg aaacaagtca atttatggga agcaagaaat aagctctttt cacagctttc
    15421 tcttggcatg agacagcgac ttgggattgc ccgcactttt ttaggaaatg cgaaatactt
    15481 actattagat gagccaacaa atgggcttga ccctatgggg ataaaggaca ttcggatatt
    15541 attacgtgat aaattaaaaa ccccaaagca ctgtattatt gtatcaagcc ataatctcac
    15601 agaaattgcg gcaatcgcag atatacttat ctttatccgt aatgggcaga ttatagaaat
    15661 gattgaaaac aaatatgatg agaaagaatt ggaagttctt tatgaaaatc ttatgacttc
    15721 cataactacg gaggaagtac aatgaaagtt ttaataaaga acgaatttac taaattgaaa
    15781 cgtgaatggt ttgtattatt tttacttctc ctttcatggc tacctgtttt aactggcgga
    15841 gtgggggctg tctttaacaa tagtacaaaa accgtaagtg atttattttt ctttatgaat
    15901 aatcaatttt ccatgttttt ccctatggta attgttattt tgacaggttc gcttttttat
    15961 caagaatata aaaataaaac ctatataaac tggattactt acggatattc aaaacaacag
    16021 ttattcagtg caaaaattat cgtcggattt gttattgaga ttgtatttgc cgcctcgcta
    16081 atatgcctgt ttcatatttt gattttaatg ctgaaaatcg caggaaaagt ttctgttgat
    16141 attcaagaaa ttttatcctt aaccgtagga tttgcattag aagctataat tgttattctg
    16201 attacaactt gcatagcagc aattatcatc aatataagca gaaatatcat tgtaacgagt
    16261 gttataggcg taatttatgg atttgtgtcc tgcttcttta ttggaagtga atttggatat
    16321 gttattccgg ggagttttgc ctatcgttta tctatgtatt tttcggatag ttctacatat
    16381 tatgaattgg caaaacaggc aacaatcggt ggctgcatta gcagtataat ttcatttgga
    16441 ctaatgcttt ttatgggaat atttattttt acccgaaaga aaaaaatcga aagctaatga
    16501 ttgccggacg acggcaaaag aaaaaaaagc cgtcgtaatg cagatatatt ttcacgcgcc
    16561 tttatagcgg tggctttgat tttagagccg ccgtttcttt ttgcataaat ttagcaacga
    16621 cgaccccatt tgaccttgca atcagcatgg cggcatatag gaggttgccg ttatgctgag
    16681 taaaatagct tttgcttata tggcaaaaga aagtcttttg tcaaaaaaag tttgtacctt
    16741 acaacgggat attccgggca gtggtatgaa ctgtcaaatc aattaaatac tgctgttatt
    16801 tcctatgcgt ctgtctgcac tttgcaggca ggcgcatttt gcattttaca gaagattttt
    16861 caaaaacttt gctctctttt tggcaaagca aaaagtcgtc tgtattatcc cgcgaaaagg
    16921 ggaggtacta ccgcctttcg gcagaaagga ggtgaacacc atgacaccta atcgcaggga
    16981 atttgaaaag caatgtgcgt ttcaaaagtt ctgtaaatca gtgctgcaca atgaagcgtg
    17041 caacgcccat gaagaaattc gtcggcgcag agttcgggaa gttgcttttt ctgaccttgc
    17101 cttgcatgag gagcggcagc tttataccgt cgataagtat tttcaagacg aagaagtaga
    17161 gccgtcttat caaatggcag gaaaagaaat aaccccaaaa ctgctgcttg aagctatccg
    17221 ggctttaccc gaagaacggc gcaaaattgt actgctgtat tactttgagg gattaactga
    17281 tatagaaatc ggaaagcagc tcaatctctc aagaagtacg gtacagtatc gccggacaag
    17341 ctcctttgag cagttaaaaa aatatttgga ggaaaacgct gatgaatgga ttgaatggta
    17401 atcaaaacga ctacccggaa aatgcccttg ttccctatcc cgttattttg gcagcgagca
    17461 aaggcgaccc ggacgcaatg aagattgtat tgcagcattt cagcggctac atagcaagtc
    17521 tttccatgcg gaagctctat gatgagcgag gaaatgttta ttttggagta gacgaagaaa
    17581 tacgcgaaag gttgcaagca aaactaatga gggcaatcct cacatttagg gctgaataaa
    17641 ccaacgcggt attggaacgc ttcccccttt tccgttccat atcgcaggac agccctctgc
    17701 tctttgacaa agaaagcggc gcaatagaac ggcgacgcag tataaggcaa atcggatacg
    17761 ttccttttgt gccgagccat gcggtgggta cgccatgacc tttttcttaa ccgaaaagcg
    17821 agcgagaaat accacaccgt aaagcaggga tagcaccctg cgggcgataa cgcacaaaat
    17881 acataatgat acttccttac agccatagtc cgagcgttag aagcgtcgca ggcaatgggt
    17941 agggcttcgg cagaccgccg gaggggtgca agtcccatga ggttacgcta atagccgtcc
    18001 gattaaagcc tatgttacag attgactttt gacccattaa gaaaggggga cgacaaattg
    18061 aacaataacg acgtgccgat ttgggaaaag tacactctta ccatagaaga agcagcaaaa
    18121 tatttccgta tcggagaaag caagctgcgg aaactggcag aagaaaatcc cgtcccggac
    18181 tgggtaatga tgaacggaaa ccgtattcag attaagcgta agcagtttga aaaaatgatt
    18241 gatacggtgg acgcaatctg atagtgaaat cgagccttga atgtggtaca atatagtcaa
    18301 gcatatcaag gctctttcca ttatggaaag gagcataacg atgtcggaaa aaagacggga
    18361 taataaaaat cgtattctcc gcaccggaga gagccagaga aaagacggga gatatgccta
    18421 caaatatata gatacctttg ggaaaccgca gtttgt
//
LOCUS       DAEPUT010000081        18414 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.083, whole genome shotgun sequence.
ACCESSION   DAEPUT010000081 DAEPUT010000000
VERSION     DAEPUT010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18414
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.083"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(204..1301)
                     /locus_tag="KRL22_003008"
     CDS             complement(204..1301)
                     /locus_tag="KRL22_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH1273459.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            1594..3120
                     /gene="glpK"
                     /locus_tag="KRL22_003009"
     CDS             1594..3120
                     /gene="glpK"
                     /locus_tag="KRL22_003009"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH1273460.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            3161..4276
                     /locus_tag="KRL22_003010"
     CDS             3161..4276
                     /locus_tag="KRL22_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBH1273461.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(4557..5321)
                     /locus_tag="KRL22_003011"
     CDS             complement(4557..5321)
                     /locus_tag="KRL22_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH1273462.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            5580..5670
                     /locus_tag="KRL22_003012"
     tRNA            5580..5670
                     /locus_tag="KRL22_003012"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5614..5616,aa:Ser,seq:gct)
     gene            5758..6546
                     /locus_tag="KRL22_003013"
     CDS             5758..6546
                     /locus_tag="KRL22_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HBH1273463.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEISE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            6567..7307
                     /locus_tag="KRL22_003014"
     CDS             6567..7307
                     /locus_tag="KRL22_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH1273464.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKVGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            7483..7857
                     /locus_tag="KRL22_003015"
     CDS             7483..7857
                     /locus_tag="KRL22_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273465.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKVNKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            7949..9409
                     /locus_tag="KRL22_003016"
     CDS             7949..9409
                     /locus_tag="KRL22_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBH1273466.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAKKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            9462..12491
                     /locus_tag="KRL22_003017"
     CDS             9462..12491
                     /locus_tag="KRL22_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1273467.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            12568..14634
                     /locus_tag="KRL22_003018"
     CDS             12568..14634
                     /locus_tag="KRL22_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH1273468.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQNEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    15297..15507
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15733..16548
                     /locus_tag="KRL22_003019"
     CDS             15733..16548
                     /locus_tag="KRL22_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH1273469.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            16576..17253
                     /locus_tag="KRL22_003020"
     CDS             16576..17253
                     /locus_tag="KRL22_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH1273470.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            17312..18034
                     /locus_tag="KRL22_003021"
     CDS             17312..18034
                     /locus_tag="KRL22_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH1273471.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
BASE COUNT         7241 a         1956 c         3279 g         5938 t
ORIGIN      
        1 aaaaaacgat tgcgtcaaaa atataaaata aattaaaaga aaaagattat attgaaggaa
       61 aaagacttga aataggggtg aactttacat attatagttc acccttatac aaaaatataa
      121 aatataattt attataggaa aatttaaaaa aatcagtcta tttaatttat actgatatat
      181 tgtaggattt tacaaacaaa ctgttatata acttttttta tctccaattt tgattttaag
      241 atatctaaga atttataaca atcttctgga tatatttctc ccatatttgc tacttggaat
      301 atgttagcat ctaggaattt gccttttcct ggatagacaa catagccact ttccctttct
      361 agccctaata taaactcatt tacattgatt tctttaggta gaaatacaga tgttactgta
      421 ttagacatat acttatctgg aagtaaaaat gttagaccca attcttccat accattcctt
      481 aaaatagcag aacattcttt gtatctttct attttactgt catcttccaa aaattcagtt
      541 aaagcttcat taagggcaaa tattaaagta acattaggtg tatttggtgt ttgagaagat
      601 gatttagcaa ctttatagtg tttataaaga ttaagataca cattcttaca ttgattttct
      661 ttaatatttt gtaaaatact ctctttagca caaaggtatg cagaacctgg aaatgctcca
      721 agagctttgc caccaacacc tgttattata tctatattaa actcttccac atcaatatat
      781 tcacctgctg aggcacttat tgcatctaca aaaaatattt tgttatactt tttagcaagt
      841 tttcctagtt cagggacggg atttatcatt cctgaactag tttcatggaa caccatagca
      901 attactttta tatcagaatt ttcaattatg tatttttcta aaatgtctag gtccgggtat
      961 tctgcccatt caaaattagg tttatatgtt tttacattat aagtagataa tatttcttct
     1021 agcctttctc caaaaacacc attactaact agcagaactg catcttcttt gtcaaagata
     1081 gaagatagta cacattcatt tacagatgtt ccagagccag atacaattaa tgagtagtaa
     1141 ttagaagttg cattatatag tttattgatt ttttgttgtg tatctttgaa taaatccata
     1201 aactcatttc ctctatggca tatatcatag tgaagaagtg aatttctgac tttatctgta
     1261 accattactg gtccaggact gaatagatat gtttttttca ttgtaaagcc tccttaaaaa
     1321 gttaaattta aatttttgaa tgactgatta tgtgtaaata ttaaaatgtt atgtgttatt
     1381 ttaactagat tatagaataa aataatgaat attgcaataa tgattcaata aaaatacttt
     1441 tttaatcact ataattaaaa ataacaaaaa atattgtaat gaatattgca taaatccaca
     1501 tgatgatata aaatataaat aacttgaata gattatatat tcaaaaaata aaaaagaatt
     1561 tattaattct gaaaataaag ggggacattt aaagtgaaat atgtattagc aattgaccaa
     1621 ggaacaacag gaacaagagc agtattgata aacgaaaaat cagagtttgt ttttagcgat
     1681 tatatggaac atactcaaat atatccacaa tctggatatg ttgaacatga ccctatagaa
     1741 atttggaata atacaaaaac tgtgagtaat aatgtattac aacaggcttt tgaaaatgga
     1801 atcaatgaaa gtgatataaa aggaattggt atagataatc aaggtgaaac agtaatgtta
     1861 tgggataaaa atacaggtaa accactttac aatgctattg tgtggcagtg caggagaact
     1921 tatgattatg tggaaaattt aaagaatata ccaggtttag aaaataagat aatagataag
     1981 actgggttaa ttatagaccc atatttctca ggtacaaaaa ttaaatgggt aatagataat
     2041 gtaaaaggtg taaaagaaaa aattaaaaat ggagaagtac ttgcaggaac attagatagt
     2101 tggttaatat ggaaaatgac aggaggaaaa tcttttttaa ctgatgtatc tacagcagca
     2161 agaacaatgc tttttaatat aagagatatg gattgggata gagagttgct tgacattata
     2221 ggagtaccta gaagtatttt agcagatata atgcctacga gtggtgattt tggaactaca
     2281 gataaggagg cattttgtgg ggtttctata aaaattactg cttcaatggt agaccaacca
     2341 gcagctttat ttggcaatgg atgttttgaa ccaggaatgg ttaaaaatac ttatggtaca
     2401 ggatgtttcc tatatatgaa tataggtgag gaactaaata tagcaggtaa tggtattttg
     2461 acaactgttg cttggaaaat aggagataaa gttacatatg cttatgatgg tggagtgtat
     2521 atagcaggtg ctgcaataca atggcttaga gatggcattg gagttataaa aaattattca
     2581 gaaactgatg acatggcaaa ttccatatca agtactggag gtgtatattt tgtaccagca
     2641 tttgcaggta tagcagcacc ttattgggac caatatgcta gaggtacaat ggttgggata
     2701 acaggaagta ctaaaaaaga gcatatagta agagcgactc ttgagtctgt tgcacttcaa
     2761 gtcaaagatg ttgttgattc tatgaattta gcctcaggga aaaaaataaa aatgttgaga
     2821 gtagatggtg gaattactaa aaataacttt acaatgcaat ttcaatccga catattaggt
     2881 ataccaattg aaattgcaga aaatcctgag acgacagtac ttggagtagg atatatggca
     2941 ggtctttctt gtggtgtctg gaacagtatt gatgaaatta gaagtgaatt tacaataagc
     3001 aaaaaatata ttccaaatat gactactcaa aaaagagaag aaatattact tggatggaac
     3061 caagcagtaa aaagagctat gaattgggaa aacgatacca aaaaggtgtg tgctaattaa
     3121 gttacaatag agtattttac atgtatagga ggaattaaaa atgccctttg ataaaattat
     3181 attatacata atggctgtgg gagtgctttt aggagcgtta gatagaataa ttggaaataa
     3241 atttggactt ggcgagcagt ttgaagaagg gtttaattca atgggtccat tggctttagg
     3301 aatggttggt atagtttgtt tagctccagt aatttcagat gtactaggtc ctataataat
     3361 accaatcttc aatctctgtg gagctgaccc atctatgttt gcaactattt tagcgaatga
     3421 tatgggaggg tatccattgg ctatggaact tgcacacaat aaagaggcag gaatgcttgc
     3481 aggattggtt gtgtcatcca tgcttggatg tacattagta ttttcaattc cagtaggact
     3541 aggtcttata gaatatgaag acagaccatt ctttgcaaaa gggttactga taggcttgat
     3601 aacaatacct tttggaggta ttataggagg attaatagca ggatttaact tatcaatggt
     3661 aattataaat atgataccag tgataatatt ggcagtaata ttggcagtag gtttaaaatt
     3721 taattctacg cttatgataa atgggtcatt agtttttgga aaatttatat ctatattgat
     3781 aacgataggt ttgggagcag cagcatttca agaaataaca ggtatagtac ttataaaagg
     3841 catgacacct ataagagaag gtattcaagt aattggaagt attgcaatcg tgttattagg
     3901 tacttttcca atattacatt tattagttaa agttcttaat aaaccactta caatagtggg
     3961 tggaaaatta ggtatggatg ccactagtgc agcaggatta gtttttactt tagccaatag
     4021 tattccagta tataaaatga tgaaagatat gagtccaaag gggaaagtag taaatactgc
     4081 ttggctggtt tgtgctacag cagctttggg ggaccattta ggatttacag caggagtagt
     4141 tccagagatg attacacctg ttgtaattgg aaaattggtt ggaggagtat tggcaattgc
     4201 acttgctata cttatgacaa aagatttaac cttggaagaa gaacaaagta ttaaaatgaa
     4261 gaaagatgca gtgtagaata aacaatactt aagtcaaatt taaattattt taaagtagga
     4321 gtttaaataa ctaaaaataa attaaaaaga cagacaatta aaaaataatc gaataactaa
     4381 aacttataaa ttaaataaaa tggcaatcaa ataactaaaa atgataagct aactgaaagt
     4441 agttacataa ttaaaatata gagtatagtt tagacataaa tggagctaaa taaataatta
     4501 tttggctcct taattttaat ttattacatc aaggaactaa aaatcaatca tataagctaa
     4561 ttatcagcta tgactaaagg tattcctttt tgagaaaact ctattattat attatggtct
     4621 atactagcag aggtaataat agtatctata tgttctatag gagctactga tgcaaatgaa
     4681 tttataccaa acttaggagg ttcgacaact actatagatt ttctagacct ttcaatcatt
     4741 ttttttctaa caagtgcttc ttctaagtga tagtcagaga ttccattttc aagagtgata
     4801 cctccagcgc ctaaaatagc tttatcaaca ttaaattgtt caatagctga cagtgtaagc
     4861 ggaccagaaa aagaaccttc agtttctcta agatagcccc caagcacata tacttttata
     4921 ttagtattca taagttcgtt tgcaactaaa attgagttgg ttattacagt tagattcttt
     4981 ttatctttca aattttttga aacttcaagt acagtagttc cagtatccat aaaaatagta
     5041 tcatttgtat ttataaactc actacattta atagcaatct gttttttatc gtttgagttt
     5101 attttttttc ttttaacata gttaagttct acgctacttg ctataactgg tatagcacca
     5161 ccataaactc tttttaaaag accgatactc tccatatggg ctaaatctct tcgtgcagtt
     5221 tctattgata tatcaaacat ttgaactatg tcatttattt taattatatt atctgatttg
     5281 agaatactta aaatcttctc atatctttcc tgtggtaaca taaaatatcc tccttggact
     5341 agtattattt tagttttggc ataacttaca attaagtcag agtttaggta tatttgttaa
     5401 tgtatgtata tttatcaaat aatattataa gtgttatgca agataatttt accatattta
     5461 aaacttacat ttaagcaaaa aagtaaaaat agatgtttaa taattcaaaa taactcaaat
     5521 tttataaaac aattgactaa aatatgattt tattatataa tttactagta tagagatatg
     5581 gagaagtact caagtggctc aagaggatcc cctgctaagg gattaggctg ggtaaccggt
     5641 gcgagggttc gaatccctcc ttctccgcca attattaaag gctattttta ttaaagatag
     5701 tctttttata atgtcataaa tgattagata tgtataacta aagaaaggag ggaatagatg
     5761 acaactttaa tttttttcat agtggggata gcatctttgg tagttgcttt tgttattgat
     5821 gggggacatg ttggagcatt atttgtattt tcatcagcac ttgttgtgtt tggtggaact
     5881 ataggagctg ttggagcttc gactccattc cctgtgttta aaaagtctat aaagataatg
     5941 ttattagctt ttaaaaataa aaagcctaat aacatagaaa atataatcta tttcaaagaa
     6001 attgcaacaa aggctaggaa agaggggctt cttagtattg acaaagaaat aagtgagaat
     6061 gatgaattag acccttttat tagaaaaggg cttgaactta tggtagatgg agtggatgca
     6121 gttactataa gaaatatatt ggaatcacag atacagataa catcaaaacg acataaagaa
     6181 ggaatagcaa tttttgattc agcaggggga tatgcaccta cactggggat aataggtaca
     6241 gttatggggt tagtacatat tttaggtaat ctttcaagta atccagatgc attaggacct
     6301 caaatttctg ttgcattctt ggctactttg tatggtgttg gttctgccaa tttaatatgg
     6361 ttaccaatag catcaaaact taaggctata aatcaacagg aaataagtga aagacttttg
     6421 gtgatagaag caatattatc catacttgaa ggtgataatt ctaatttaat gacagaaaaa
     6481 ttaaaaatat ttttaaattc aaaagaacta attgaacttg aagaaattgg tggtagagct
     6541 gaataatata aaaggatgga atgtttatgt tgtatgatga agatgaaaaa gaagaaaaca
     6601 atgagcgatg gcttttaact tattcagacc tcataacatt acttatgatt ttctttgtaa
     6661 taatgtattc tatgagtaat gttgatgcgg agaaatataa acaattatct caatctctaa
     6721 attctgcttt tggtggttct tctggagtta ttgaaggtgg taatagcaag atagaaccag
     6781 tagttgaacc aggaagtaat gatttagata ctttacaaaa tgctaagttt aaaaaagttg
     6841 gtgaagaaat ccagaagtat ttaaacgaaa atggtatggc taattcagta tcattaagag
     6901 ttcaagatag aggattagta ataagcctta aagatacaat actatttgat acagggaaag
     6961 cgattgtgaa ggataattct agagataaga ttattcaaat aggtaagatg ttaaatgaaa
     7021 tgaatagtta catgagagta gaaggccata cagacaatat gtctataaaa aattcagagt
     7081 ttaagtcaaa ttgggattta tcagttatga gagcaaccaa tgttgttcaa cttcttattg
     7141 acaatgcagg tatagcacca gataaattat ctgctgtagg atatggtgag tttagaccaa
     7201 tagcagaaaa ttcatctgaa gaaggtaggt caaaaaatag aagagttgat atagttttag
     7261 ttgatagtaa atatgataat gtagaaaatg tttcaaagga taaatagtta aattagctgt
     7321 ctcaatacag aattaattct aaaggagatg gcttttttat gcgaaaatca aaaatagata
     7381 catagtaagt tacctttttg taggaatata tggtatctta aatatataat atttaaataa
     7441 tgtataagct caattaaaaa atttatagag gatggaaaat aaatgggaaa taaaaataaa
     7501 aatactaaat ataaagataa aacaagagaa aggtataata aaaaagttga gaatttaaat
     7561 aaagaaaaat taaataaagt taataagcaa tctaagaagg tagataagat tgatgatatt
     7621 attaataaat ctagtattgt attatgtgta cttctagtag tgttttcatt gctttactta
     7681 tttaaactgg ttcaacttaa tataataatg atacttttag taattacagt agctattcaa
     7741 caaggattgg tgtcatttgg tgcatttaga aataaaaatt atgtaaaagc tttattttct
     7801 atatttgtaa tagtatgttt cttaattgct tttaaatatg ttgtaaatcc tgtttaaata
     7861 tatcaataaa cgttctataa ttaatataaa tagtgaagtt acagttttaa tgctattata
     7921 aattttataa tttgaaggag tagattttat gaataggtgt aagtttgcaa aattaattat
     7981 cacatcaatg attgttttat tacttacagg atgtagttta aagaaggaag ataattataa
     8041 gttagaccca gaaaatccga catcaataca aatttggcat tattataatg gacagcagaa
     8101 aatggctttt gataagcttg ttaaggaatt taatgacact gtaggtgcta aaaaaggaat
     8161 tattgttgaa gcattcagtc aaggtaatgt agttgattta tcagagaaag ttttagattc
     8221 tgcaaataaa aaagttggtt ctgaagatgt accaaatata tttgcagcat actcagatac
     8281 tgcatatgaa atggataaat tagggttact agtagatatg gataagtaca taagtaaaga
     8341 agaattaaat gaatacatag acgaatatgt agaagaaggc agaataaatt ctaaggatga
     8401 gtttaaactt ttcccaattg caaaatcaac tgaaattttg atgttaaata aaactgattg
     8461 ggataaattt gcaaaagcta caaattcaaa tataaatgat ataaaaacaa ttgaaggatt
     8521 agtagagaca tcaaaaaaat attatgaatg gacagatagt ttaacgaaag agcctaatga
     8581 tggtaaagca ttttttggaa gagatgcttt agcaaattat attattatag gaagtaaaca
     8641 actaggagta gaaatttttt ctgttaaaga tggtaaagtt acactaaata ttgatgaaaa
     8701 agttatgaaa aaactatggg ataatttcta tgtaccatat ataaatggat attttgcttc
     8761 ttatggtaag tttcgttctg atgatgcaaa aacaggtgat atattagctc ttgtaggttc
     8821 tagttcagga gcagcatact ttccagatag agtaatgcta aatgataatg agagttataa
     8881 tattgaaaca tctgtttttc aagcaccacg ttttaaagga gaaggaaaat atgctgtaca
     8941 acaaggtgca ggaatggctg taacaaaatc tactaaagaa gaagaatatg catcagtaga
     9001 atttttaaaa tggtttacag ataaagaacc taatataaaa ttctctattg cttctggata
     9061 cttaccagta aagaaaaaaa cgaatgattt ggatgttata aaagaagtta tgaagaaaga
     9121 taatttgagt ttatctgata aagttgaagg ttcaatagcc tcatctattg aacagattaa
     9181 cagttgtaat ttatatacta ataaagcatt tgatggtgga actaaagcta gacaaatact
     9241 tgaatattca atgcttgata aagctaaaga agattcaaat aaaataaatg aattagtaaa
     9301 aagtggaact tctaagaagg atgcagtagc acaatttaat aatgataaaa attttaaaac
     9361 ttggtttgaa agttttaagg ctgagcttga aaatgctata aaaaaataga tgaattggca
     9421 gttagtgtgt tgacgagcac aaaggtatag gtggaatggg tatggaaaac aatctaagaa
     9481 aaaacaattc aataatgaaa aagatgatat ttcccctaat tattgttatg ctaattcaaa
     9541 caagtttatt ttgtgccaca attttatggg gaggaactat taagaaatta aatgataatt
     9601 cgtttgacat cttaaatgaa agagtaatta atcgtaaaaa ttatatacaa aatgaaatgt
     9661 tacaaagatg gtcaaataca agtgaaacgg aagctacaat taattcttct gtaaaaaaag
     9721 tattaaatga aaaaaatgcc ttaattgagg atgtaggcaa caatgaagaa attaacaaag
     9781 atattataaa aagcatatca aatgatttaa tatatctttt gagaaaaaat tctgttacag
     9841 gagcttttat aatcctaagt gacaaaaata ttaacgataa gtcaatagat agtaaaggtg
     9901 aaataagtag gacaggattg tatataaggg atttagaccc taagtttaat ccaaatgata
     9961 attctgattt gttaattgag agaggttcat cagatatagc aagaagtttt ggaatatcta
    10021 tggacagtta ttgggaacct aagttttcat ttaaaagtga aaatgagcaa gatggagatg
    10081 atttttttta taaaccattt agagctgcaa ttgataatcc aaatgtatca agttctaatt
    10141 taggatactg gggaagtaag tttttattga caaatgcagg tgataggctt atgacatata
    10201 cagttcccct tatttatgaa gatggaactg tatatggagt acttggaata gatttaagtg
    10261 taaattattt aagagaatta cttccatatt cagagataaa tgggaataaa aagggtaatt
    10321 atattttagg tgtagataga aataatgata tggcctttga aaatgtaatt tcaaatggat
    10381 actcattaaa agaaaaattt tgggatggtt tacattctaa tttagagcag aaggaatcgt
    10441 ataaaaatat atataagatt aaaaataaag ataatgaatg tggtaatggc aacatttatg
    10501 ctagtgtaca atacttagat ttatataact ccaatactcc atttgaaaat gaacgttggg
    10561 ctcttttggg tattattgaa gaaaaaagtc ttttgtcatt ttcaaaaagg gtagagaaat
    10621 tagttataat atctatagca atttctttat taataggtct aataggtatt tacattgcat
    10681 caagattatt tacaaaacca attgttcttt tagccaacaa agttagaaac agtaatccat
    10741 caaaaccagt aaatcttgat aagataaata tatctgaaat agatgaatta tcttcagcta
    10801 tagagttgct cagtgcaaat gttgcagatt cttcgtcaaa attatcacag attattgaaa
    10861 tggtagatat gccaattggg gcttttgagt tatacaaaaa cgcagagaat gttttttgta
    10921 caaaagaatt ttttagcgtg tttactactg aaatcaaatt tgaagaatat ggatatatgg
    10981 aaaaaaataa gttcctgaaa aaattaaggg gactagataa atatttgcaa gaaagttatg
    11041 aaacagaaaa tacatatata tataagtttg aatctaaaga taaaaaactt aagtggataa
    11101 gaatgaatat ctttgaagat gagctaaagg ttcttggtgt tgttgttgat gtcacaaaag
    11161 aatttattga gaaaaggaag atagaatatg aaagagattt tgatatttta acgaatcttt
    11221 taaataggag agcttttcat tcacagatac aagaaaaatt taagaataaa gatgaactta
    11281 agatagcagc atttattatg tgggatttag ataatctaaa atatattaat gatacatatg
    11341 gacatgatgc tggtgatgaa tatattaggt gtgctgcaga catacttaag aagtttatat
    11401 catggaatgg tatagtatct agactttcag gtgatgagtt ttatgtattt atatatggat
    11461 atgaaagcaa agatagtata agagatatta ttaattctgt taagaaacag atgaataata
    11521 ccttattaaa acttcatgat ggaacagaat ttaaaataag ggcatcagca ggaatttcct
    11581 ggtaccctga tgactcaacc aactatgatg aattaatgag atacgcagat tttgctatgt
    11641 atcaaattaa aaatacaatc aagggtgaag ttagtgaatt tgatattaat atatataata
    11701 aggattcatt cttattgagt aatagagaag aattaaacaa gttaattgat ggtcaattag
    11761 ttgagtatgc atttcagcct attgtagatt gtaaaggtaa agtatttgca tatgaagcac
    11821 ttatgagacc taaaataaaa acttttagtt caccaataga tgtcattaga ttagctcgtt
    11881 cacagtctaa attatatcaa attgagcgta ttacatggtt taaagcactt aaatcattta
    11941 aaaaatacaa agaaaaattt ggcgattgca aactgttctt aaattctatt cctaataata
    12001 atttgtcaaa agtagatttt gaggaaattg aagatttata tggtgaatat ttaaatagag
    12061 tagtactaga aataacagag aatgataaga ttaatgaaga ttttattgag aaaaagaaag
    12121 catatataga ccattggaat atagaaattg ctttagatga ttttgggaca ggttacaacg
    12181 gagatgctgt actattatat ataatgccag actatgtaaa gattgatatg tctattgtaa
    12241 gaggtattga taaagatgaa aacagacaga aaatattaaa aaatcttatc tcatattcta
    12301 acgaaagaaa tattaaagtg atagcagaag gtgtagaaac aaaaggtgaa atggaaacac
    12361 taattaatct tggagtagat tatatgcaag gctactatat tagtaaacca tcatttatac
    12421 ctgaagatat aagcgacaaa attaaaaaag aactcaagat atgtcatgaa aataggaatg
    12481 atgtggttta atagaggaaa aattaaattt atttttatga acttttagtt tataattaaa
    12541 aagaaaataa tataattata aatcaaggtg gtggagctaa taatcacaac aaatatagat
    12601 ataagaaagt taaatgaaaa tcaattagaa gcagttgagc atatagatgg gccttgcatg
    12661 atacttgcag ggcctggttc aggtaagacc agagtaatta catatagaat agccaatatg
    12721 gttgtaaaca aaaacatagc accaacaaga atcttggcaa taagttttac caaggcatct
    12781 tcaatagaaa tgaaaaatag agctttgaat ttaagtgatg atataagact taataaggta
    12841 acctatggta cttttcactc tgtatttttt aaaattctaa gatactttga aagatacaac
    12901 ttagacagta tatttgatga aaagtcaaag cgaatgacaa tcaaggcaat cctaaaaagt
    12961 ttaaatatag agaatgctga tgatgatgag aatataggac aagttataaa tgaaatttcc
    13021 tatgtaaaaa atgaacttat ggataaaaat gaatttaatt cagaagtatt aacaaaagat
    13081 gagtttttaa aagtatacaa cttatacgaa gaacaaaaat ctaaagttaa taaaatagat
    13141 tttgatgata tgcttataag aacttattat ttacttttga acaataagtc tgcactagaa
    13201 atggttagaa atgtgtataa atatatattg atagatgaat ttcaagatat aaataaagta
    13261 cagtttgaag ttttaaagtt aatttgtagc ccattaaaca atatatttgc agttggagat
    13321 gaagaccaaa gtatatatgg atttagaggt gctagaccag attttttgct tgaatttgaa
    13381 caatacttta ataatactaa aaaaataata ttagatataa attacaggtc taaaagtgag
    13441 atagttcata ctgcaaatag acttatcgac aaaaataaaa atagatatga aaaaatcatt
    13501 aagtgtagtc agggggatgg aggaagtgtt acctatattt ctccgcatga ttcagaggaa
    13561 gaagccttat atattgccag ggaaataatt gacgaaatac aaaaagatta tgtagagtat
    13621 tcagattttg cagtaattta tagaactaat atacagtcaa gagcattagt agatgtattt
    13681 atggatatga ggattccatt tgtagtaaaa gactcagtaa ttacaatata tgaccattgg
    13741 gcaagtcaag atatactagc ctatttaaga ataggtatta atccaaaatc aaataaagat
    13801 tggttgagaa ttataaacaa gccttttaga tatatatcca aagacagtat aaatatggtt
    13861 aaggatgaaa aagactttat aacagcatta ataaataagt gtaatcttca tcctaaacaa
    13921 gttaaaacaa taaatgattt ggaaatagat ttaagttatt taaatacttt aaatcctaaa
    13981 aatgcaatat cttatattag aactagtctt gattatgata gatatgtttt agattattgt
    14041 agcaacagaa agataaagac taatggactt gtagagatat taaatgaact tgagagttca
    14101 gcaactaatt ttaatactgt tacagagttt ttagagcata ttgatagagt aaagactgag
    14161 ttaacggaaa ataacaagaa taagcagaat gagggtgtca tatttacaac tatgcatagt
    14221 gcaaaaggat tagaatttag aaatgtttat attataggtg taaatgaagg aacaatacct
    14281 catgaaaaat catatgatat ttgtaaggaa gagaaaaaag aagaacaatt agaagaagaa
    14341 agaagactta tgtatgttgc tattacaaga gctgaagaaa agttatgtat aagctctact
    14401 ttaaataagt atggtaagaa agttgataaa tcattattta ttaatgatat aaaatctcca
    14461 acgaaaaaag aaattgacag tattggtgta ggggataagg tataccataa aaaatttcat
    14521 gaaggagaaa taattaaaaa agatggaatt atgtttacaa taaagtttaa agatagagag
    14581 cgaatcttgg atttgaaaac ttgtttattg aagaatataa tttatactat ttaatttaga
    14641 tagaaatata atgtattatt tattatgtgc aagacaaata gatatgtgta aaatgtatta
    14701 tttaacttat tagaaaaaag aaataagggt ttaatatatt atttatagtt gtttagaaaa
    14761 agcaacaatg tggaaaatat tatttagtat tattaaagaa aagcaacaat gtgaaagata
    14821 ttatttagtg taatttaaga aaaagcaaca gtgtgaaaga tactatttag tattattaaa
    14881 gaaaaagcaa cagtgtgaaa gatattattt agtgtaattt aagaaaagca acaatgcgaa
    14941 agatattatt tagtattgtt taagaaaggt caacagtgtg aaagatacta tttagtatta
    15001 ttaaagaaaa agcaacagtg tgaaagatat tatttagtgt aatttaagaa aagcaacaat
    15061 gtgaaagata ttatttagta ttgtttaaga aaaagcaaca atgtgaaaga tattatttag
    15121 tattatttaa gaaatagcta aaaatatgaa atatactatt tataattaca caaataatat
    15181 caataaatat aaacagtagt atttagataa tttacaagta aaaattatta aaaaaataaa
    15241 aaacttattg acaaaaatat tataaggaag tacaattgta ttaacaattt aaggaaacaa
    15301 atccaatgat agagaaagta gcatatatgg atttacagcg agttaggggt tggtgtaagc
    15361 ctagcaatga agtctatgtg aagagagctc tggaggagat tatcagaaac tttagtatga
    15421 taattggttt acccgcctta agggattgag aggataagta cttacttatc aaaaagagtg
    15481 gtaacgcgga tataattcgt ctcttagctg taaagctaag ggactttttt gatttaaaaa
    15541 taaaaatatc catacagctt aaatgctaac agtcacaaat tttgaaagta atataagtat
    15601 ttatcaataa gagtggtaac gcggtaaagt cgtctcttag tcattaaaga ctgagagact
    15661 ttttttgtaa ctcgaaacat ttaagtatta aaatctgagg gaaattataa ttaaaagaga
    15721 ggggtagtta aaatgaaagt atttaaaaaa ttattaagtt taggattagt attaggattg
    15781 acattatcgc tagtaggatg tagtggtgga ggagaaaaaa caaagttaga acaaataaaa
    15841 gacaatggaa aattagttgt tggtactagt gcagaatttc ctccatttga atttcataag
    15901 gtagtagatg gaaaagattc aataaaagga ttcgatataa tgttggctga agaatttgca
    15961 aaagagcttg gtgtaaaggt tgaaattaag gatatgtcat ttgatggatt aataggtgct
    16021 ttaaatgcag accaagttga tattgttctt gcaggtatgt ctccaacacc agagagagaa
    16081 aagagtgttg atttttcaga attatattat ttaagtagaa atgcagttat agttaaagat
    16141 gcagatatag acaaagtaaa aactgaagat gatttaaaga aacttagagt tggagttcaa
    16201 gcaggaagta tccaagaaga atatgtagtt aacactttaa aaatgacaac tacaaaatct
    16261 ttgaaagcaa tacctgattt aattacagaa ttaaaaaatg gaaacataga tgcagttgtt
    16321 actaatgaag cagtttcttt aataaatgtt aaaaaatatg atggaataaa aatggcaaat
    16381 actgaagttg ggaaagatgt aacagaaggt atggcagcag caatcaaaaa atctgacaat
    16441 aacaaagatt ttatagaatt attaaacaaa aagataaaag aattacaaga tggcaagaag
    16501 atagaagaat ttttaaatga agcatctact gaagctgctt caaattagta agaaagttat
    16561 gtgggagatg aaattatgag tttagatttt agttttttaa gtagatttgg gacttctttt
    16621 ttggaaggaa caggtgtgac agtatcaatt tctcttgtgg cattatgctt tggatttata
    16681 ataggtataa ttatctgtat ggcaaaaata tcaaagagca aagtattaag agcaatatca
    16741 tcaatctata ttgaggtttt aagagggaca ccattattag tacagatata tatagtatgg
    16801 tttggtttac ctcaattagg aataagattc cctatgttgt ttggtatacc aagtgaattt
    16861 atagctagtg catttgcatt atcagtaaac tctggtgcat acgtggcaga gatacttaga
    16921 tcaggtatac aatcagttga taatggacaa atggaagcaa gtagatcatt aggattaaat
    16981 tattggtcaa ctatgagata tataataata cctcaagcta taaaaaatat attaccttca
    17041 ttagcaaatg agtttattac acttgtaaaa gaatcttcaa taatatctgt aataggagtt
    17101 gttgagataa tgcgtactgc tgatatagta aaaaatgcag catttagagc attagagcca
    17161 ttaatagtag cagcagcaat ttactttgtt ataacattta ctctatcaag attagttgga
    17221 ttattagaaa agaaactatc tgtgtctaac tagatgagag catgtttagc atttagggaa
    17281 aacatagaat agtaaaaagg aaagtgataa tatgattaca ataaaaaatt taagtaaatc
    17341 ttttggagat ttaaatgtat taaaaaatat agacttagaa atcgctaaag gcgaaataat
    17401 ggttatagta ggtccaagtg gttctggtaa aagtacactt cttagatgta tgaatttact
    17461 agaaatacct acaggtggag aaataatatt tgaaggaaaa aatttggtcg ataaaaaaac
    17521 taatattgat gaggttagac aaaatatagg tatggtgttt cagaacttta atttattccc
    17581 acataagact attttagata atataacatt agcaccaatt aaattaaaaa agatgactaa
    17641 ggaagaagca gaaaaaaaag cagaaatttt gttgagtaga gttggtcttt tagataaaaa
    17701 agattcatat ccatcacaat tatctggagg acaaaagcaa agaatagcaa tagctagagc
    17761 acttgctatg gaaccagata tgatgttgtt tgatgagcca acatctgctc ttgacccaga
    17821 aatggtaaac gaagttttgg atgttataaa agaacttgct aaagaaggta tgacaatggc
    17881 aattgtaact catgagatgg gatttgctaa ggaagttgca gatagagtta tttttataga
    17941 tggaggaagt atacttgaag ataatactcc agaagaagtt ttcggaaatc caaaacatga
    18001 aagaacaaaa gcgtttttag caaaagtgct ataatatata aaaaggatgt tattgatatt
    18061 agaaattcaa tacatccttt tttagtgatg gttaatatta attttaaaat taaagttata
    18121 ttaatattaa ctttattttt acgatttttt gcagaaaaaa aaagagctcg gggtaagctc
    18181 tttttttcca ccgaattaat ttccgttact aatccgattt ttaataaata taaaatatat
    18241 ccttatgaaa gggtattggg aatagatata ttaactaact agggttacca gggggataac
    18301 cttaatttat tataacaaaa tgcgacacaa aaatcaatat tttttttgaa ataaattata
    18361 aaagttattt ttataacaag taagcttata aatttaactt ttatagtaaa aata
//
LOCUS       DAEPUT010000082        18152 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.084, whole genome shotgun sequence.
ACCESSION   DAEPUT010000082 DAEPUT010000000
VERSION     DAEPUT010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18152
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.084"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..465)
                     /locus_tag="KRL22_003022"
     CDS             complement(<1..465)
                     /locus_tag="KRL22_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1273472.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRL"
     gene            complement(500..2575)
                     /locus_tag="KRL22_003023"
                     /pseudo
     CDS             complement(500..2575)
                     /locus_tag="KRL22_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004610982.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5011 domain-containing protein"
     gene            complement(2590..2835)
                     /locus_tag="KRL22_003024"
     CDS             complement(2590..2835)
                     /locus_tag="KRL22_003024"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273473.1"
                     /translation="MKERVDSHVHTLLRLRQTDRQTDRQTDRQTDRQTDRQTDRQTDR
                     QVNSALFSILSIINRTHRLSSYKGEFVRFSMQRIYEK"
     gene            complement(3070..3705)
                     /locus_tag="KRL22_003025"
     CDS             complement(3070..3705)
                     /locus_tag="KRL22_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273474.1"
                     /translation="MEGCAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRTEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYRTPYQVVKMINPNSKEDMELLREVLRNNHFDDEDE"
     gene            4217..5359
                     /locus_tag="KRL22_003026"
     CDS             4217..5359
                     /locus_tag="KRL22_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1273475.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYVCDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYKNGGADCRCKNYENVQGGKLSEKKRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVQFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSKKQEMLVEQMCTDIADVIESEGVFYE"
     gene            5352..5558
                     /locus_tag="KRL22_003027"
     CDS             5352..5558
                     /locus_tag="KRL22_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273476.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKGAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            5637..6830
                     /locus_tag="KRL22_003028"
     CDS             5637..6830
                     /locus_tag="KRL22_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1273477.1"
                     /translation="MKEKRRDSKGRILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKEKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNLQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDCVRKNPFDFKLSEVLENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSR
                     ETIQAFQRVMKKRPKAEPFVIDGQSNFLFVNHKGKPKVAIDYNALFVRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            7037..8365
                     /locus_tag="KRL22_003029"
     CDS             7037..8365
                     /locus_tag="KRL22_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273478.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCIGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(8493..9683)
                     /locus_tag="KRL22_003030"
     CDS             complement(8493..9683)
                     /locus_tag="KRL22_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1273479.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEVLLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(9785..11164)
                     /locus_tag="KRL22_003031"
     CDS             complement(9785..11164)
                     /locus_tag="KRL22_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1273480.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            complement(11195..12403)
                     /locus_tag="KRL22_003032"
     CDS             complement(11195..12403)
                     /locus_tag="KRL22_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273481.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            complement(13428..14882)
                     /locus_tag="KRL22_003033"
     CDS             complement(13428..14882)
                     /locus_tag="KRL22_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH1273482.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYEMPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLGKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            complement(14902..16773)
                     /locus_tag="KRL22_003034"
     CDS             complement(14902..16773)
                     /locus_tag="KRL22_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1273483.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQSTTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIEGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            complement(16763..17623)
                     /locus_tag="KRL22_003035"
     CDS             complement(16763..17623)
                     /locus_tag="KRL22_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1273484.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKTLNIKASDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSE
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
BASE COUNT         5880 a         3334 c         2541 g         6397 t
ORIGIN      
        1 taaacgattc tgccactcgt taaccatagg ttctagctgt tctgttaagc tagaaacgaa
       61 ggacttagag acggatttac cacaaagttc ttccacaatt tttgatactt tacgagttga
      121 aacgcctgat acatacattt ccaacattga agccatgagg gctttttcgt ttcgttgata
      181 acgttcaaac actgtgggtg aaaaatggcc atcacgtgtt ctgggtactt ttaattctag
      241 cgtgcctaca cgtgtcgtaa agctgcgctc ataatagcca tttcgttgac tttgtcggtt
      301 ttctgttcgt tcatattctt ttgcttgaat atattctgtt cgttgatttt ccattagttg
      361 attaaatacc gttgttaaaa tatttttaga aacgtcatcc tttacagaat attcaataat
      421 gctttgaatc tcttcgcttt tcagtgtaaa atgtacttgg gtcatgtaaa agtcctcctg
      481 ggtatgtttt tgtcgttaat aaaacagcta atacaccggt tgaaccagca aacatagaag
      541 taaacaatcc tacgtttgtc atatcacctg tttttacagg gttcttttgt ccgctaggct
      601 ttgttggagt agttggcttg ctcggtttct gtggctgttg tggacttaca ggtttatttg
      661 ttactttttc ttttacggta actgtaattg ttttttcagt aattgcacca tttttatcta
      721 ctacacggaa agttacatga taagtgccag ccttagaagt atctacatca tttgcaataa
      781 tgttatcttt tgttaaaata atcgttccgt cctctttatc tgttgctgtc acatttgcca
      841 atgggtcgaa cgtatcgcct acattcaatg taacatcatt tgctgaaatg attggagcag
      901 agttaaggtc gcctgtattt tgtttcacag ttacagtaat cgttttttta gcagaagctc
      961 cgtttttatc tgttacttta taagtcacat ggtaagtacc agccttagaa gtatctacat
     1021 catttgcaac aatattatct tttgtcaaag tgatagttcc gtcctcttta tctgttgctg
     1081 ttacatttgc caatgggtcg aaagtatcgc ctacattcaa tgtaacatca tttgcagaaa
     1141 tagttggtgc tgtattatct tctccttgtg agtttaacga taattctact tttaaaacaa
     1201 cgtttccgtc tttataagta ccgcaatcat actcataagt aactggtttt tttacatcat
     1261 ctaccgttat aattcctgta tctttatcta aagttccatt tgcagtaact tttacttttg
     1321 aaatatctat tccttgttca acatcttttt ttaagtcgat tttattccct ttaatatcaa
     1381 tataaccgtt gcctacaaaa gcatgattat tttcaagaac tttattctct ccgacattta
     1441 accagtataa atcatcgcaa attaattttt taatttttgt gtttttactt atatcaagac
     1501 ctcttatccc ttgttcaaaa atttcaccgc aacgtagcat ttcaagttct aaattattgc
     1561 ttaaatctaa ttttttaata gttgtatcat gacaaaaaag gcgtgtcagt tttgtgtttt
     1621 ttgttacatc taattcagct atatttgtca tataacatga tagttgtttc aaattagggt
     1681 tcttacttat atcaagtgtt tttacttttg tatctcctat atctaaagtg actaattgcg
     1741 gattatgtgt gacatcaagt tccattaatc ctgtattgct acaagatagt tgttctaagt
     1801 taggattgtt tgttacatct aaattggaaa tagaggtact atctgcaaat aacgtattca
     1861 atttttcatt cttagataca tcaagactgt taattgatgt attatcgcaa acgaaagctt
     1921 ccaaattcgg ataacgtgtt aaatcaacgc ttcttacttt tgaagaacga caatctaatc
     1981 tttttaaaga tgagttttta accggactta agtctgaaac agaagtcgta gaaacatcta
     2041 aagactgcaa atttgttaga tattgaatac cctctaatga agatatcgtt ttcatatcat
     2101 gcaagtttaa gaattgggct tttgatattt catcaacaga taacacacta tcgccgtctt
     2161 tatcaaattc tgcaatgatt tgttctctaa atactttgtc tggaaaatgt gcttcatcaa
     2221 tagcaatgct tccagctttt acttctgtat ttttgcttgc ttcaacggtc ttatcttcgg
     2281 taaccacttc tttttctggt gttgcaggtg tttcctgttt tgtactttct tcttttaaag
     2341 tttctgcatt ttcagcagtt tcttcctgtt ccttgtctgt tatattctct tgtacttctg
     2401 cgttttctgt tttctgttcc acaggaactt gctctgtctt gttttcttct acaacggctt
     2461 cctgcacaac ttctgtgttt tcctgtgcca tgacaggagt aggaagccct gtaagtgcag
     2521 ttgttgttcc aatcatcaat gcggaactta ctgcaaggac ttgttttttc ttcatagttt
     2581 gttcactcct tatttttcat aaattctttg catagaaaaa cgcacaaact cccccttata
     2641 actggataat ctgtgcgttc tgtttattat tgatagaatt gaaaaaaggg cagaatttac
     2701 ttgtctgtct gtctgtctgt ctgtctgtct gtctgtctgt ctgtctgtct gtctgtctgt
     2761 ctgtctgtct gtctgtctgt ctgtctgtcg caagcgtaac aatgtgtgaa catgactgtc
     2821 aaccctttct ttcaaaaaaa ttcaatcctt gcttctatac aaaaaacatt atactggaaa
     2881 caaacacctc tttcaatctt tttatgcgtg caagataaaa aaattgagac atcacacttt
     2941 tccttttttc ctcttgagta cccacaacag aaaagaaaaa gccctgtcaa gagcttgcca
     3001 ccattggtgg tgctttgcac tcttgatcgg gctttttgtt tgctgtatct tctcgcaaga
     3061 ggaaaaagat tactcgtcct catcatcaaa atggttattc cttaatactt cccgtaacag
     3121 ttccatatcc tcttttgagt tcggatttat cattttcacg acttgataag gtgtcctata
     3181 tttatgtccc tctatgcttt ccccaaacat atccatactg tataaatcat catagcggtc
     3241 tagtaatttt tgaaacttca aatgctggat aaattctttg attgggtaaa ggtcggacgc
     3301 ttcaatgctt ttcccgttga tatagtctgt aatgtattcc cgtaactttt ccaactcata
     3361 ttccagccat tcttcctcgc tgtcaaagaa gttatcatag tgtccgtgtt tcagttctgc
     3421 atttagacgt tcttctgttc ttaaaaactg acagacttct ttttcagact gattgacata
     3481 cttccattct cccgataata attcattcgg cgttacgtcc agcacttcca ttatcttttc
     3541 cagcgtttca taagcaggat agttcaaccc tctttcaatc ttggaaaggc tctgcatatt
     3601 gataccgatt ttgtccgcaa gttcctgttg tttcattccc ctaaattttc ttatggtctg
     3661 tatattattt cctaaatggc ttattttcat tgcacaaccc tccatatctc gttatatctt
     3721 cactgttata agtctatcat gcttaatatg atttgtaaag acaaaaaaag atattgacaa
     3781 ataagcatat aagaattact atgctattgt gagtgaataa gcacaatagc atgaaataca
     3841 aaaacattca aaaagaaata cccatctgat taaacccgta gatatgaata ttggttgaaa
     3901 tggaacttgt tagaaaaggc aaaacaggac ttgctgacaa agtatttctg acacggtggc
     3961 ggaagcctct caggcttacc gccatgacac cttgtgtcaa ggggaagaaa tgctttgtcg
     4021 gctggcgagc ctgcgagcct tgactgtgcc cccgttatct aacagggggg cactatttca
     4081 caaaagacaa gtcaaaaacc atacaacccc aaacctgtga gtagtaatga gaagttttaa
     4141 gaagatagta atttcacatt cttttgaata gtggtttaca ggtatttcaa ggctgttgtg
     4201 ggattggagg aatacaatga acaatttaga atttgcactt gaaatgaaga acaaacgtct
     4261 tgcaagcggt ctttcacaag gagaacttgc aagtcttacc catgtatcaa gatatagtat
     4321 caaccgcttt gagaacggaa aagccaacgc aagtaaagaa acacagaaca ttatcctgcg
     4381 ttgtctgaat tactatgtct gtgataagcc tttttatctg ctcgttgatt atctgtctgt
     4441 ccgttttcca acgactgacg cattagaagt tatccgaaag gtgcttggca tgaaagcgga
     4501 ctattttatc cattatgact atgggtatta tggctataag gagcattatg cctacgggga
     4561 aatcaaggtc atggcttctg atgatgaaca catgggtgta tttttagaat taaaaggggc
     4621 aggctcacgc aacatggaat atgtcttaca ggcacagaac agggattggt attcattttt
     4681 aaaccgctgt cttgactgtg gcggtgttat ccgacgtttt gacttggcaa tcaatgatat
     4741 gtgcggtctg ctggatattc ccgttttgtc tgaaaaatac aaaaatggcg gtgcggattg
     4801 tcgctgtaaa aactatgaaa atgtacaagg tggaaaacta agcgaaaaaa aacgtaattt
     4861 agcaagtacc ctttatatcg gctcaaaggc aagcacaaaa tatttctgcc tgtatgaaaa
     4921 acaaaaggag caggcaacca aaaagaaaca tacggatatt atcaaccgtt ttgaaattcg
     4981 tctgcgtgat aaaaaggcag tacaggcagt tgaggaattg ttattgacat ataaccctca
     5041 tgggttggtg ttttacctta ttactgattt tgtgcaattt cccgattatc cgctgtggga
     5101 gatattcatt tcccatgaca gtttaccttt tgaaatgaac cccgtacctg tcaatatgga
     5161 acgcactctg caatggctgg aaagacaggt catgccgtca atcgtgatga tagaggaaat
     5221 cgacaggctg acaggctcaa actacatgaa aatgattgat gaatgtaccc acctttccaa
     5281 aaaacaggaa atgcttgtag aacagatgtg tacggatata gcagatgtaa tcgaaagtga
     5341 gggggtgttt tatgagtaat gcacaggata ttcccgtatg ggaaaaatat acccttacca
     5401 ttgaagaagc gtcaaagtat ttccgtatcg gagaaaacaa gttaagacgc ttggcagagg
     5461 aaaacaaggg cgctggctgg ctcattatga atggcaaccg catacagatt aaacgccgac
     5521 agtttgaaca ggttattgac aaattggacg caatctaatg caaatgagcc ttgtatgtgt
     5581 tatgatgaac acaagtcata tcaaggctct ttccaacaag gaaaggagca gacaccatga
     5641 aagaaaaaag acgggatagt aaaggacgta tcctgcatac tggagagagc caacgaacag
     5701 acgggaaata cttatataaa tatgtagacg catttggaaa cacaaaatat gtgtatgctt
     5761 ggagattgac acccacagac ccgacaccaa aggaaaaacg ggaaaaaccc tcacttcgtg
     5821 aactggaaca gcagataaga cgggatattg aggacggtat cgacagcaca ggcaagaaaa
     5881 tgacgctttg ccaactctat gccaaacaga acttacagag ggcaaatgtg aagaaaagca
     5941 cacaaaaaca acgggaacaa ctcatgcggt tattgaaaga ggacaaatta ggtgctagga
     6001 gcattgatac aatcaagccc tctgacgcta aagaatgggc gttacgcatg aaagacaagg
     6061 gcttttccta taacaccatt aacaaccata aacgctcgtt aaaagcgtca ttctatatcg
     6121 ccatacaaga cgattgtgta aggaagaacc cttttgattt taagttaagt gaagtcctag
     6181 aaaatgatac caaagagaaa gtcgcattga cagaggaaca ggaacaagcc ttactctcat
     6241 ttatcaagac agacaatgtg tatcacaagc attatgatga tgtgctgata ctgttaaaga
     6301 ctggacttcg tatctcggaa ctgtgcggac tgacagtagc tgatattgat ttcaagaatg
     6361 aagttgtaat tatcgaccac cagttactaa agagcaaaga acagggctat tatattgaaa
     6421 cgcctaagac gaaaagcgga ataagacaag tgccattaag tagagaaaca atacaggcat
     6481 ttcaacgggt tatgaagaaa cgcccaaagg cagaaccatt tgtgatagac ggacagagca
     6541 atttcttatt tgtcaatcat aaaggcaagc ccaaagttgc gattgattac aacgccttat
     6601 ttgtccgtat ggtaaagaaa tataacaagc accacaagga caatcccttg ccacatatca
     6661 caccgcatac gctacgccat acattctgca caagactggc aagcaagaac atgaacccaa
     6721 aagatttaca gtatatcatg ggacattcaa acattagtat cacaatgaac tggtacgctc
     6781 atgcgtccat agataccgca aaatcagagg ttcagcgtct aatcgcatag aagtatttac
     6841 cacgatttta accacgcttg atagcgaaaa tataagaaga tagacctaga tatgtgaggt
     6901 ttaccacaaa agcaaaatgc ccgtagagcc tataaaataa ggctttgcgg acatttaagg
     6961 agatataaaa agatagtcaa aaagacatat ataatttaat ataaaataat tataataatt
     7021 gaaaaggaag taatctatga tgaaaatagc agtcataaca accgaatttt taaaagagtt
     7081 tgtagataat tctataaaaa agttaaatat taatgcagaa attgaaatat atatctatag
     7141 agatttttct catgttggag atttatattt agaaatagaa gataggtttg atggatttgc
     7201 agttagtggc cccatcccca aaaaagctat tacaaaaaag gctggaacta ttaaaaaacc
     7261 tctagttgat tttggtactg acttacaaag ttactatgat atgtttctaa agcttatctt
     7321 taaatataat acattagatt tttccagagc atactttgac ttaacagact gggcagataa
     7381 tccaaaagat atatcatatt atttatcaaa tggcacattt ggagacttaa tggatagtat
     7441 tgatgaaaat gcatctaaaa tgagtttatc tgacatagca aaacttgaaa aaaagattgc
     7501 aaaaaaacat attaatctat ggaatgaagg gaaaatcgat ttttctacta ctcgttttag
     7561 tagtattgtt cctatgttac aaaatgcagg agtaaacttt catttcatat accctgatat
     7621 agatttatta aaaaatactt ttaataactt aataaaagat attcatttac atagaatgaa
     7681 gggaaatcaa ccaagtgtaa tatatataac agttaaagat acaaattatg atgactctac
     7741 tctagaccaa gtttataaaa tattaaatag tattaaaaaa gataaattaa ccgattttat
     7801 aattgaaaaa aatagtaatt cttttaaaat tttcactaaa tgtgaaacga ttaaatcatt
     7861 aactaaaaat tttactgcat gttatataaa agaatctatt gaaaatagta caaatattaa
     7921 agtatgtatt ggatatggaa ttggtaatga tataaagcaa gctatgtcta gtgccataag
     7981 tgctaataag gaatctaaaa taaatccttt aaattacagt ttcttagtta acgaaaatta
     8041 tgagacaata ggacctttac tgtgtgataa gttacttact gtttcaaata aagtaactcc
     8101 acatataaat acaattgcca aaagttctaa attgtctact cttactattc aaaagattat
     8161 atctgttact gaaattctac aaagagatga agttactcct aaggaattat cttcatgttt
     8221 aaatgtaaca gttagaactg ctaatagatt tctaagtagt ctcttaaagt ctggaaacgc
     8281 tactatatta tatgaaaaac aaaactcaac aaaaggcaga cctgaaaggg tatacaaatt
     8341 atttatatca gaaaataaat attaaaatcc aaaatgcata aaaatatttt atcatctaat
     8401 attaagtaaa attatatatg actttctaaa aggtatatct ttgcatcttt ttaagatata
     8461 ccttttatga tatttaataa tattttatgt tattatctac taaaattatt ttctaaccat
     8521 tttactgcac aatgagcaaa taaagctgaa ccataaacta atccctcttc attaaaaatt
     8581 gctttaggat tatgcatacc aaaattatat ccctgactaa tacttcccat tccaatccat
     8641 aaaaatactc ctggaaccct tagtaaaacc tctgaaaaat cttctgaacc cattgcagat
     8701 ggaaagtcta ttacattttc atttcctata acttctttaa cataagatac aatctcatct
     8761 cctacatcca aatcatttat aactgcagga gtccccattt taaactccac tttagcattt
     8821 cctccaaatg atttagctat tcctgtagat atttcaataa ttctattttt taatttttct
     8881 ctaacaaatt ggtcaaatgt tcttaaagtt cctgacatag atgctttatt tggtatagca
     8941 tttggtacgt ttcctgcatt aaacatacca atagttaaaa ctacaggttc tttctgaggt
     9001 ttttctcttg aaagtatagt gtttaatgct atttgtatat gcgacattat gtttattggg
     9061 tccactccaa attcagggct tgctccatga gttgcttttc cttctactgt tatttcaaat
     9121 atatccgcag atgccatagc tggaccacgt gaataagcta cttgacctgt gttaagaaat
     9181 ttacccacca tactgtgaaa tgccatagct gcatcaacct gaggattttc taatatacca
     9241 tcatcaatca ttgattttgc acctctggta gtctcttcat ctggttcaaa tacaaacttt
     9301 actctacctt taagtaagtg cttattatcc ataagtattt tagctgctcc taagagcatt
     9361 gctgtgtgat tatcgtgtcc acaactatga gatgcatctt tattcttact tttaaaaggt
     9421 aaatccgtct cctccataat aggaagtgca tccatatctg cccttaataa taaggtcttt
     9481 ccaccatttt cactgtctaa aacagctact attccattat tagacgtcaa tttcggagaa
     9541 tatcccattt tttctaaagt actggtaaca aaggttactg ttttcggtag attgcaacca
     9601 atttcgggat tttcatgtaa ataccttctc catctaataa tttccccttc tattgactgc
     9661 gcttctttaa aaaaattttt catattcctt cctcctaatc agatagcaaa atctcacttt
     9721 cttttagtaa tgaaatgatg ctgatataaa aattataatt ttatatatta aatttcatgt
     9781 ctttttaagg agttggaata tcatctggaa taggacattt atatgtttta ccattcatag
     9841 atttatcaaa ttcttctttt gcctttttag ctatctctgg attatttaat attttagctc
     9901 caaacatagc cataatcttt gatgcatata tcataccttt ttctcctata gaacttcctg
     9961 cacaagatgt aaactgccag ctatgacctg gtgctcctag attcgtacac cctgtaaaaa
    10021 agtatgctgt cggaactata tgcattacat ctccaatatc agtagagcca taactattaa
    10081 agtttgtaac atttcctcca ccataatata gatgagttcc ttctggcaaa ttatatttac
    10141 ttatcatagc cttatattgt tgtgggcttt gtctatctaa ttcagctgca aaatccaatt
    10201 cctctcgagt ccaaggctct tgtttaatct cattcataca ttctgataca agatttgcta
    10261 aaacatgatt gtttaaagta ttataacatc ctcctaaaaa ctctacttca acttcagttt
    10321 cagtcatcat tgcagctcct tttgctacct ttacaagtct ttcatatgta ctttctacag
    10381 cttctctact taaagctctt gtataatacc atactgatgc tttatcagga actatgttgg
    10441 gtgctactcc tccatctgta attgtataat gaatccttac atcagaagta acatgttctc
    10501 tcaaataatt agctcccaca ttagtaagtt ccacagcatc tagtgcactt cttccatttt
    10561 gagggtctga ccctgcatgt gcagtctttc ccttaaagtg aaactttaca gagttaacag
    10621 ctgttgaagt accaattgta gcttcactaa ttttatttgg atgaaaattt atagctaagt
    10681 ctaacccttc aaacgctcca cctctagcca taaatccttt acctgttaat tgttcttctc
    10741 ctggacatgc ataaaatact atagtcccac ttaagttatt ttctatcatc tctcttttaa
    10801 gccctactac tgcccctaca tgtgctgtac ataataaatt atgcccacat ccatgaccat
    10861 atgcacccaa ttcaaatgct tcttgctttg ttgaaacttt ttgatttaaa ccaggtaatg
    10921 catcaaattc tcccataaaa cctataactg gtttacctga accaaaacta gctctaatag
    10981 ccgtggctaa acctcctaca cctacttcca catcaaatcc ttcacttctt agaaagtttg
    11041 ctgtattttc acatgcttta aattctttaa atgctttttc tggattttcc catattttct
    11101 tacttaaatc atcaagtttg aatctttttt tatctatctc atttatagat atacttccta
    11161 tcatttccta ttcctcctat aagtatattt actatcaacc aaatataatt ggacctatta
    11221 tactagcaaa tgccactgat gcaatggtta cagtaacaaa tcctcctata atcatctttg
    11281 gtaataaata atctgttgcc ctttgttttt cttcttcagt tccttccata gcatcaatac
    11341 cttcgttgga aattatctgt gttgcaggat aagctagcat acaagttaca ccaattgcag
    11401 ctgacattct tggagaatat cccaatagtt ttcctacaat tgcagtaaat aatattataa
    11461 atacagaacc tacaacaagt attcctatag ttggaacaat catcccaaac aatgctgttg
    11521 gagttacctt agcaagtcct ccaggtaaca tcaacataca accaaacatt ataattccat
    11581 tagattgaga tttatctaaa attccttttt ctaaaaaacc tattcgtgta aaaatcaacc
    11641 ctactaacaa acatgctata ttaggattta aataatagtt tgcaggggta aatcctggta
    11701 ttaaagtagc caatcctaca aaattaccaa tcatagcaac aaatgaaagc tttgcaagat
    11761 atactaaagt agatgatttt ttacctaaat cttctttaaa aattctcata cttggaagtt
    11821 taaaattact ttttgactca tctttcaaaa aatccccgtt atctctttta aattttaatt
    11881 ctttatttat acaatatgta gttatcggaa tgccaaagaa cttttgaaat gataatacta
    11941 gaattacaaa tgcagcaagt tcaggtctat ttgcagcttc tgcaacagtt gttacgataa
    12001 taccagcaac agtagaaccc gctattggag gtgctgctat taaagcatac tctctaccaa
    12061 ataacatact acccactgtt aaacagccaa cccctattcc tacaatacct actaatgcaa
    12121 ttacaaccgt tttccattca tgacataagt cttcaagatt tataagtgtt cctaagttag
    12181 ttattaataa agctatacca aagttgctca ttgcagctaa tatccctgat gctcctgtaa
    12241 tgtcttttgg taaaatattt gtccaaaatc ctagtaaaaa tataatacat acaaataaca
    12301 atgttgaaat tgcacctttt gttttcttag ataaaaactc actaaaagca taaatcatta
    12361 cacatacagt aaagcaagta agtggattcc aaaaattttc cattgttgtt tcctcctaaa
    12421 tataataatt ttttatcaat aaaacaataa ttataaaatg tatattatgc agttattctt
    12481 aactacatat ggtatagctt gatatttttt gatgatatta tatacgtcct aaattattcc
    12541 taaaatatct aaataaatat aactagagtt aactctctaa atattaacta tagttatcaa
    12601 cttactagat ttctttttga tttttacttt ctacataatt ttacgagtta gaattgtact
    12661 tcaactattc tctatattag tatacatgtt ggaagactta tatttattta aatattagat
    12721 atagaatata tttttataaa cgtcttaaat tattcttaaa atatctaaaa cgaaataata
    12781 atatacccat taaaccaata ttatcagaat atacttcact ttaagtcttc tttatataga
    12841 aattttatct attagtgcat cccctccctt gtaaattaga ctatttctaa gcgaatttag
    12901 atatcttatt cctagagact attactaaaa acaaaaatta tttattatat taaatcaatg
    12961 ataagccata ctttaaaatt ctttctatac aagtataatt tatcatataa tgacatctat
    13021 acctttatct ttatagtagt cctaaattat tcttaaattg acaataaaaa taatttcact
    13081 atttataaaa atacttgttt ttatattgtc aaactattct taatatagat tataatttta
    13141 aatcttttct ttgtcaatat actctgacat ttttccagaa aatttataaa gttatatagt
    13201 gagtaaatca tactattttt atataatgag taaattatac tatgaatatg tctaaatatt
    13261 tacttaagta taaacataaa aaatgtgtat tctccttttt atagtaattt tagttgccat
    13321 tacttttaag aagaatacac actttacttt aaagacccta tactctattt taaatgcttt
    13381 actagacact aattaacatt agttcctaac ttctatttat cttattccta ccctactact
    13441 atatccgtag aaaaatctaa aacttctcca ttagatttta ttacttcttt gtaccaatca
    13501 aatgattttt tcttatatct cttaaaactt cctttgcctt catcatctaa gtcaacatag
    13561 ataaatccat atctcttact catctgacct gtagttgcac tgactaaatc aattggtccc
    13621 cacatcaaat atccaaaaca ttcaacatta tcttcttcaa ttgcagactt catttgagat
    13681 agatgcttac ctaaatattc aattctataa tcatcattta tagttccatc ttcttcgatt
    13741 ttatcatatg cccctaaacc attttctgta attaagatag gtaattgata ctttctgtaa
    13801 atatagttca aggtaaatct taaacctata gggtctattg cccaccccca cttactttgt
    13861 tccaaatatg gattttgaat cccaccaaat aaagatttat cacctgataa attttctttt
    13921 ggagtagata cacttgaaaa ataataatta agtcctataa aatctaactt accttcttta
    13981 aatgcttttt tgtcttcatc agtcacttca atagttatat tatttttttc atattctttt
    14041 aatttatatt gtggaaactt cccattgcac attgcatcaa tttgataata atcacggtca
    14101 ttatctaaaa atgcatttaa cacattacta ggattacaat tgtatggata aattggattt
    14161 agtccaaata cacatccaac tttattgttg ggattgattt ctctagccaa ctttgcaacc
    14221 tttacacccg ccaaagtcat attataccct acatttgcca atgtttgaac cttattttct
    14281 atttcactat acttaatacc tgctatcata taagtaaaaa tatccgagtg ctctgtttga
    14341 gggtcaatat ggttcatctc attaaatgta acccagtact ttaccttatc atcaaatctt
    14401 cttattacag tctcactgta ctttaaatac aaatctataa gttttctgtt attccatgaa
    14461 ccatatttat gtactaaatt cataggtaat tcaaaatgat atagtgttac aataggttct
    14521 atattatttt ctattaatgt atctatcaga ccttcatagt atttaatccc taattcatta
    14581 ggattttcat catctccatt tggaaaaatt cttgaccaat ctatagatat tcttaatgca
    14641 ctaaatccca tttctttaaa taaagctata tcttctttat atctattata aaaatctatt
    14701 ccattatgag atggataatc caatttttct tctattttat cagtaattac tcttggcatt
    14761 tcataagagc ccttagttac aaaatccata attgcaggtc ctttgttgtc actatcccat
    14821 gaaccttcac attgatgggc tgcaatactt cctccccaga aaaatgtatc tttaatattc
    14881 atgaattttc cctcctaaaa tttatactat tacagttaat aattcttctg attcatcatt
    14941 tgatgagatt acatctaaat aatcgctagt atttgtaact acagttatta tagtagaatc
    15001 aaagccttcc tctataattt tatcagattc aaatactgct aaagcatctc cttttttaac
    15061 cctttgattt tgtgttacaa gactttcaaa gaattttcca tctaagttta cagtatctat
    15121 cccaatatga attaatattt ctaatccttc atcagtcact ataccatatg catgtttagt
    15181 tggaaatact atagttatag ttccatctac aggagatata acagttgatt ttgattcact
    15241 aggtataact ccaacccctt tacctaatgc tccagaggaa aatgctttgt cattaacttc
    15301 cccaagtgca attacctgac cttttgcaac atttccaata ctaatagttc ttgaattgtt
    15361 ctcgttgatt attagttcta attctttttc attatcaccc ttaacttctt ctttttcatc
    15421 tgaaggtatt cctagtaaat aggaagctgc tgttgctgct acaaatgata ctactacact
    15481 tattatcata aatgtaaagt tagatacctc tcctccaaca agatacgttg gtaatgcagc
    15541 taatccccaa accattccat atgttttaac ttgagctaaa ccttctatta aaccacctat
    15601 acctccacct atcattactg ctacaaatgg tcttctatat ttcataaaca caccaaacac
    15661 tgaaggttct gtaactccca taagtgcact aaaacttact gtaccaaata attgtttttg
    15721 ttctttattc ctagttttta agaaatatcc aaacattgca ccacaaactg caatatcaga
    15781 tattgttgca gcgcccataa aaattgggtc ataccccaat gttgtcacag aatttaaaga
    15841 tataggcata gtaaagtttg ctgcaccaaa gactattaag agtggttgta aagctgcata
    15901 cagtgcaaca acactccaat tacccaatgt atcaattaaa aacatacatg catagtttaa
    15961 tccatcacca atccacatac caataggtcc aaatacagtt aatgtaactg atagagttat
    16021 tattaaagat aatactggaa ctaaaaaata gtgtagtgct ttaggtaata tttttttcaa
    16081 accttcaatt ataattccca ttgcccatac tcctaaaagt attggaataa aactgtttgc
    16141 ataagttgta gactgtaaat ttataccaaa taaacttaat ccttctacac catctattga
    16201 tgaagataat aacgtaactg ctaatactac tgctatatat ggatttacat taagtctttt
    16261 tgctgatgct attgcaatta atactggtaa gaagtgaaat gtagcacttc ttaatgtatc
    16321 taatatttga tatgtaggac tgtcactctg aagtatgcca gacatattta aaagtgctaa
    16381 tatacttgca agtataccag ctgcaagtag tacttcaatt actgaagtca tagtctctga
    16441 gactaccaca aagatggaat taaatatacc tttgatacct ctaattccct tttttctttc
    16501 actttttata cttgattcac ttgaacttaa acctatcata gacataaact cgttatatac
    16561 atctacaaca tgagtaccta ttataatttg ataagcaaca tcattagaaa ctacatcaat
    16621 tactcctttt aattttttaa tttcttctgt ttgagcgata ctcctatcat ttaaagtaaa
    16681 tcttaaacga gtaacacaat gcgctaccga ctttatattt tcttttcccc ctataagttt
    16741 tattatattt tcatttaaat ctttatattt catctgattt tgcctccagt ctttgagtca
    16801 ccctatttat atgcaacatt aaataagttt cttcacttat agatatatcg acattaaatt
    16861 gtgattttat atattttctt atcttttgaa cacttccaaa tgactttgga taaagttgac
    16921 ttacttgttt atataaatct atagaattat cttcatctat tgaagcttcc tctgacataa
    16981 ttctttggat aaagtactgt agatgagtag taaatctcat ataatttgtt gaagtttcat
    17041 ctagctctac attaaaatga tattttatta tagaaactat atctgctaaa gttctcaact
    17101 ctacaattgt actatcatga gactctttat ttacctccat atttacaaaa tgaagtgcta
    17161 ttgatactgc ctcatcatca ggaagattaa ttcccttact atcaccaatt aattttagtg
    17221 catgcattcc aatttcaaaa tgctttggat aaaatctttt aacattccat accaaaggac
    17281 tttttataaa ttgattcttt tcacatcttt taagtaaaaa ctctaaatgg tctagtaagg
    17341 ttaagcttag ataatcactt gcctttatat ttaaagtttt ctcaccatat tcaattattt
    17401 cattaataag aactatatta ttggagtctg agttttgtag tagataacta aagtgttcta
    17461 gcatatcgta tgaatctagt atatatgttc tctctatttc attttcattt attacttgtc
    17521 ccactctttt tttaaagcca attcctttaa caaatacaat aatttcattt ttacctcttt
    17581 ttactaaggc tacattatta tttaaaatct gaattatttt catatattcc tcccttcaat
    17641 aaaaagaact caagcatata tgtatagagt atccctctat ttttcacata tatacttgag
    17701 ttctgcctgc taatcagtaa catactcaaa attatgacta cgtcgccata attaaaattc
    17761 ttttttgttt aatttcatat tctatatgtt atactatcca tataaatctg tcaacggttt
    17821 cctagatatt tttttattct ataactacaa gctctgttat gcgattatct gacaaggttt
    17881 atatactaaa ttgatactat tttaccgtca ctaatattta taatattgtc tgaaccatta
    17941 tctattttac tattatgaat tatcatagta atgcttttaa atataatgaa ctgtatgtta
    18001 acaaataaat tcttaagata tattaacata taaagtctta agtttagttt tatttaatca
    18061 ctattaagat atattaatag gtaaagcttc aaatttagtt tcatttaaat gctagtaaga
    18121 tatactaata tataaatact taaatttaat tt
//
LOCUS       DAEPUT010000083        18002 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.085, whole genome shotgun sequence.
ACCESSION   DAEPUT010000083 DAEPUT010000000
VERSION     DAEPUT010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18002
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.085"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            489..998
                     /locus_tag="KRL22_003036"
     CDS             489..998
                     /locus_tag="KRL22_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBH1273485.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            1026..1220
                     /gene="rpmI"
                     /locus_tag="KRL22_003037"
     CDS             1026..1220
                     /gene="rpmI"
                     /locus_tag="KRL22_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBH1273486.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            1276..1632
                     /gene="rplT"
                     /locus_tag="KRL22_003038"
     CDS             1276..1632
                     /gene="rplT"
                     /locus_tag="KRL22_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBH1273487.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGVEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            1942..2487
                     /locus_tag="KRL22_003039"
     CDS             1942..2487
                     /locus_tag="KRL22_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273488.1"
                     /translation="MNEKLMDCFVNPIKCKLLLEVFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            2927..4852
                     /locus_tag="KRL22_003040"
     CDS             2927..4852
                     /locus_tag="KRL22_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1273489.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWTINDKFSKTIEVE"
     gene            5253..7157
                     /locus_tag="KRL22_003041"
     CDS             5253..7157
                     /locus_tag="KRL22_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1273490.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAESRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
     gene            7770..8549
                     /locus_tag="KRL22_003042"
     CDS             7770..8549
                     /locus_tag="KRL22_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH1273491.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDIVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(8859..9680)
                     /locus_tag="KRL22_003043"
     CDS             complement(8859..9680)
                     /locus_tag="KRL22_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1273492.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADILIISLVSDDGILNDGTKLEDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEMWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(10422..11240)
                     /locus_tag="KRL22_003044"
     CDS             complement(10422..11240)
                     /locus_tag="KRL22_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1273493.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            11408..11989
                     /locus_tag="KRL22_003045"
     CDS             11408..11989
                     /locus_tag="KRL22_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1273494.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            11986..12180
                     /locus_tag="KRL22_003046"
     CDS             11986..12180
                     /locus_tag="KRL22_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273495.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(12344..14086)
                     /locus_tag="KRL22_003047"
     CDS             complement(12344..14086)
                     /locus_tag="KRL22_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HBH1273496.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGNDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQNGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            14515..15891
                     /locus_tag="KRL22_003048"
     CDS             14515..15891
                     /locus_tag="KRL22_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBH1273497.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            16202..16873
                     /locus_tag="KRL22_003049"
     CDS             16202..16873
                     /locus_tag="KRL22_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBH1273498.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            17062..17859
                     /locus_tag="KRL22_003050"
     CDS             17062..17859
                     /locus_tag="KRL22_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBH1273499.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDINIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         7041 a         2028 c         2964 g         5969 t
ORIGIN      
        1 taggacttgt tatgtagtat agtaacatat tagaatataa tgtaggattt gttatgtagt
       61 atagtagtat attagaatac aatatagaat ttgttgggta gtatagtgtt atattagaat
      121 acaatatagg atttgttatg tagaatatat agagtcatgt agaatataca tatataaaag
      181 gattttgggt ataaatttaa aaattaatag caaaatgagt agtatagaca tataattagt
      241 agtaggaagt aattaaattt ttcctaaaca aaaaaaatag ttgcaaataa tttgattaag
      301 tgatatagta aataaggtaa gaataaaaca aagaagaagt ccgcttctca ccttacgccg
      361 gaggttagta aggtaaatat aagttaaagc ttaattttaa tttaagtttg tttaaatttg
      421 gtaacttata ttgcggatga ttacgtcatc cgctttttat tttataaaaa ttttggaggt
      481 gtcctacaat tagcaaagaa ttagcaatca atgaacaaat aaaagataag gaaataagag
      541 tcctttcacc aacaggtgaa caacttggag taatgcctac taaagaagct caagcaatgg
      601 ctaatagcaa aaacttagat ttggttcaaa tctcgccgaa tgcaaatcca ccagtatgta
      661 agataatgga ttatggaaag tttagatatg agcaagcgag aaaagagaaa gaagctaaga
      721 aaaaacaaaa aactatagtt gtaaaagaag taagacttag accaggtatt gaacaaaatg
      781 atttaaatac gaaagctaat aatgctataa agttccttaa aaaaggggat aaagtcaaag
      841 ttgaacttag atttagagga agagaattag gacataaaga cataggtaaa gaagttatgc
      901 ttaagttttt agatataata aaagagtttg gagaaccaac aaaagcccct gcatttgagg
      961 gtaataatat ggttgtaatt atagatccaa aaaaatagat gattaactga gaggaggaat
     1021 ttgtcatgcc taaaatgaaa actcatagag gtgcagcaaa gagattaaag aaaacaggaa
     1081 ctggaaagtt aaagagagct aaagctttta aaaaacatat attaactaaa aaatctgcaa
     1141 aaactaaaat gaacttaaga aaatcaactc tagtaagtga tggagatgct aagagaatag
     1201 cacaattatt accatactaa gatacagatt gtaaataata actatagaag agggatataa
     1261 aaggaggtca taacgatggc aagagttaaa aaagctatga acgctcgtaa aaagcataag
     1321 aaaatattaa aacttgcaaa aggattcaga ggatctagaa gcaaattata tagaccagca
     1381 aatacattcg taatgaaagc attaaaaaat gcttatatag gaagaaagtt aaagaagaga
     1441 gacttcagaa aactttggat acaaagaata aatgcagctg ctagaatgaa tggaatatct
     1501 tattcaagat taatgaatgg attaaaatta tctggtgttg aagttaacag aaaaatgtta
     1561 tctgaaatgg ctatacaaga cccagaagga tttgcaaaat tagcagaagt tgctaaagca
     1621 aaattagctt agtattgaat catgagatgt aaagtctttg agttatataa ataattcaag
     1681 gactttttta ttttttgaaa aatacttatt agtgtcatgt acaaccaatt ttataatgat
     1741 aaataaaata agcaatacaa tagaatttta tgagatttat tataagaatt gttacaatta
     1801 tttatgatag ctataaaaag tcatagtaaa aatgatattg atgtatgttg atatatgtat
     1861 aaagctttca atcaatcttg aattaatatt atcaacatga taatattatc ttattaataa
     1921 tataaataag ggggagataa tatgaatgaa aaactaatgg attgttttgt aaacccaatt
     1981 aaatgcaagt tattgcttga agttttttca aataatcgaa ctacagctaa acaattagga
     2041 gaaaaatttc aagatatatc aaaggcaaca ctttatcgtt accttaataa aatgttgaaa
     2101 gatgatatta taaaagtggt tgaagaaaat aaaataaggg gaactgttga aaaagtatat
     2161 gctatgaagt tagatatagc tgatgatgtg aacaaaatta tagatgagaa ctctggagaa
     2221 gaatatgctc aactgtttac tcaatatatg atgggatttt taagagaatt ttatgaatac
     2281 gctgaaagaa aggaaaagga tatcctaaaa gatggttcag gattttctgt ctgtccagta
     2341 tatgctagta ttgatgagat agttgaagtg agtaaaaaaa ttgctagtat actagaacct
     2401 ctaagaaata actcacacga agaaggcaga agaatgcatt ctataggagt gataatcact
     2461 ccacctaaag aggatgaagg gaaataaatc tgatttacat ggggtagagc caatttatac
     2521 agggaatcgt tttatgattt acatatgtat ccagagcaaa gtatctctgc ttggattgta
     2581 cttcattgta tcatttcatc tatctaatga cttggagtgg tacaatgaag ttttttaatt
     2641 tttcatatta atgcctaaag aaatgaactt tagaccacat atgcaatcag gttacattat
     2701 acaattagac cagatataca aaataaaaat cagtattttt atagcagata aattgactgt
     2761 tattcttctt aaaaatcatc tattagttat tgttagcata ttgaaagaaa ttataggaat
     2821 ctattgaata aatgaatatt gcccataatc atataaactg ctatagttta aaataaagca
     2881 ggacgttaaa ttttatagta atctaaaaat ttaagagggg gattttatga aaataaaatt
     2941 tgttattatg ccattggtga tatttttaat ggtattattt gtggggtgtc aaagtacaaa
     3001 agatacagaa gttaaagcaa aagatacaga aattaaaata ttaggtacag gtgatttgca
     3061 ttcaattttg acagactcta tggtttcata tgtaaatgag gaaagggaaa agaataaaaa
     3121 tctgcttatg gtagatgcgg gagatttcta tggtacacaa agtagagaaa tgtgggaatg
     3181 gtcttctgga aaaaagttaa ttaatattaa aagaaatggt agagcagagt atgatgacat
     3241 aattaagagt agtaaagatg aagtacctat agttaaagat atggcaaagt tgaaatatga
     3301 tgctgtagtt ttgggagata atgaatttgt ttcaaatgat aagcaaagtc ttgataaact
     3361 agtttctgat tttaaaaata ataatatgcc attggtatca gcaaatatat atgaacaatc
     3421 tggagaaaat tatgtacaac catatgtaat gaaaaatatt aagacagatg agggcaatgt
     3481 aaaagttgga atactaggtc ttactataaa agaagtaggg gaaacccttg gtcttgagga
     3541 ttttgaaaag gataaaaaag ctagagagct tggagaacaa gctgattaca aaggaaaatt
     3601 atatgcaaat gatttagtag aagatgcaaa gaaatggata aaagttatgg aaaaagaaag
     3661 tccagacata atagttgcag ttgtacactc aggggaagaa cctaaaacag atagaaatcc
     3721 aggaaataga ataaaagagt tagcaactac agtggatgga atagatgcaa ttgtagctgg
     3781 tcatactcat gaaaaaatag atgaacacaa atataaaaat aaatctggag atgaagtaat
     3841 tgttacacaa ccaggttggc atggagatag agtatcagag attaatttca aattaaataa
     3901 agagaatgga aagtgggaca taaaggaaaa gtctagtaaa ttaaaaataa ttgataaaga
     3961 agtaagtata gttgctactg cagatttaca ttcacatttc tctgataaat taacagttga
     4021 ccttgttaat gaacgtagta acccaattga acctgttgta gtagatgcag gcgacttctt
     4081 agaccctcaa acagatgaaa tgactcaatg gtataaagag tggaaaagta taagagataa
     4141 taatagtgat aaaacgatta gtagatgccc aatggtcatg gatatgaatc agggaatgta
     4201 tgatgcagta gtacttggaa atcatgaatt tgtatctgaa aaagatgaat tttggtcaga
     4261 tgaacgcctt ttagatgctg ttatagagga ttttgaacag gtggcaattt ctgtgttatc
     4321 ggcaaatata tataggcaat ctggtaaaaa ttatgttaaa ccatatatta taaaagatgt
     4381 ggagacgagt gaaggtaatg taaaagtagg aatattggga cttactataa aagaagtagg
     4441 taaaggtctt aaaaatgtaa acttacaaga gcagtttcaa tataaggata aattgtatgc
     4501 aaatgattta gtggaagatg caaagaaatg ggtaaaagtt atgaaaaaga aaaaaccaga
     4561 tataatagtt gcagttgtac attcaggaga agaaccaaaa aatccaaaac atccaggaaa
     4621 tagaataaaa gaactagcaa ctacagtaga tggaatagat gcaattgttg ctagtcatac
     4681 tcatgaaaaa atagatgagc atgaatataa aaataagtct ggagaaaaag ttatagtgac
     4741 acaaccaggt gagcatggta aatattattc taaaattacc tttaaagtaa ataaagaaaa
     4801 gggttcgtgg actattaatg ataaattcag taaaacaatt gaggttgaat aactttataa
     4861 aatttataga taaagtaaat tatctgatat tgacatgata tataagataa agtttctaat
     4921 attagtataa tgcataatgt gaaatatttt aataataaga gaataaacaa gacaaataaa
     4981 aatattttaa catgtaagat atagtatgaa ctattatact aatgcttact ttataatttg
     5041 aacatattag aataagtctt atttgaaaat tttagtgtat tagagtaagt attattttac
     5101 cagtaaaaaa tattgagaac tatatgtaga tttgcttaaa aaggaattta catatagttc
     5161 ttttcgtata ataaatagta caatcttata tggtaaagat aaagtgtgat attaaatttt
     5221 attatcatcc aaaatctaag gaggagtctc ttatgaaaat aaaatttatt atagtagcat
     5281 caataatatt tttaatagta ttacttgtgg ggtgtcaaag tactaaagac acagaaatca
     5341 atgtactcgc cacaagtgat ttacattcaa ttattccaga taatttaatt tcctatgtag
     5401 aagaggagag aaaatatgat gagaatctac ttatggtaga tgcaggagat ttttttgaca
     5461 tgcaaagtgg agagatgaat aagtggttta ctggtcaaaa attagtaaga tttaaagatg
     5521 ggataccaga gtacaaaaaa atagctgaat cacgtgaagg agaagttcca ttggctaaaa
     5581 aaatggcaaa gctgaagtat gatgcagtta catttgggaa tcatgaattt gtatctaatg
     5641 acaagcagag ccttgataaa ttggtttctg attttaaaaa taacaatata ccattagtat
     5701 cagcaaacgt atatgaacaa tctggagaaa actatgtaaa gccatatgta atgaaaaata
     5761 taaatactga caagggaact gtaaaggttg gtatacttgg tctgactata aaagaagtag
     5821 gggaacgttc aaggtttaaa agttttgaac aagataaaaa ggctagagaa cttggggaac
     5881 aacctcaata caaagggaaa ttatatgcaa atgatttagt agaagatgca aataagtggg
     5941 taaaggttat ggaaaaaaaa gaaaagccag atataatagt tgccattgta cattcaggtg
     6001 aagagccaaa aaatcctaaa aatccaggaa atagaataaa agaactagca acaactgtag
     6061 agggaataga tgctattgta gcaggtcata cacatgaaaa aatagaacag catacatata
     6121 aaaataattc tggtgaagaa gtaatagtaa cacagcctgg agctcatggt aatagtatat
     6181 caaagattaa ttttaagttg gataagaaga atgataagtg gtttataaaa gacaaatata
     6241 gtgaattaaa ggtttttgga aaggaagtaa atataattac aacttctggt ctgaatccaa
     6301 aattttcaga tgaaatggca gttaatttgt ttaatgaaag agatagagat gttcaaccta
     6361 tctttataga tactggagat tttttaaata ctaatacaaa agaaatgact aagtgggcta
     6421 aagagtggca atacaatgaa aataaaggca tctataaaaa aataaatgaa tggccaattg
     6481 tatatcttgg ttatgatgct gtagtacttg gtagccatga atttacagag gataaagaga
     6541 cttttgagga aaaaaaatct acattggatt atattataga aaactttgaa gaaatgaaga
     6601 taccagtatt atcagctaat atatatgatg aatctggaga aaattatgta aaaccttata
     6661 taattcataa tgtagaaact agggaaggaa atataaaggt tggagtatta ggtcttacta
     6721 ctactgataa ggatgaagaa gacttaagta gctcaagctt aagcaaagac tcaaagactt
     6781 cgaaaattcc tgaagaaaca ggaaagttat atactaacaa tctagtaaaa gatgcaagcg
     6841 aatgggtaaa agttatgcaa aaggaaagtc ctgatgtgat tgttgcagtt gtacattcag
     6901 ataataatag tactctaaaa aatccaagta gtgaagtcaa aaaacttgca atgtcagtag
     6961 atggaataga tgctattgtt gtaggtcata cgaaaaataa ggtagaagaa catatttaca
     7021 aaaataagtc tggggatgag gttatagtaa cacaatctgg agaggattgt tattcaaaaa
     7081 taagtcttga actaagaaaa gaaaatggca agtggaatat cataaacaaa tatagtaaag
     7141 caataaaaat gaagtgaatt tattgatata taaaccatta ttaatactga ttctacaata
     7201 taattaacac tgatttttat aatataataa atactgattc tataatataa ttaacactac
     7261 tttttataat gtcatcaaca ctgattctat aatataatta atactacttt tttaaatata
     7321 atcaatactg attccataat ataattaaca ctactttttt aaatataatc aatactgatt
     7381 ctataatata attaacacta ctttttaaat ataatcaata tcgattctat aatattaaca
     7441 ctacttttta aatataatca atatcgattc tataatatta acactacttt ttataatata
     7501 atcaatactg attctataat ataattaaca ctacttttta aatataatca ataccgattc
     7561 tataatataa ttaacactac tttttaaata taatcaatac cgattctata atattaacac
     7621 tattttttat gctatataac aattattgaa aatgatataa atataatatc tcaaataata
     7681 tgaatataac atctgaatag agggtgtttt atttgtaaaa aataagttta cagtttgagc
     7741 gtataaactt atggtaaagg agaataatta tgagttataa gaagattgca attataacgg
     7801 gtgctaatag tggttttggt aaagagtttc taaagttatt aataaatgaa gaagaaataa
     7861 cagaaatatg ggcagttgca agaaacaagg cgagattaaa tcaattagta gatgaatttg
     7921 gaagtaaggt aaaaattttt tcaaaagatt tatcaaaaat agaagaagta aaagaaattg
     7981 gtacattttt aagtaaagaa aatgtatgta taaaatacct tataaacaat gctggttttg
     8041 caaaattctg ttcatacaat gatttaagta tagatgaatc tattaatatg attgatttaa
     8101 atattagtgc tgttgtagca ttgggactta tatgtattcc atatatgcaa aagggaagcc
     8161 atatcatgaa tatttcttca caagcatcat tccagccatt gccatatcaa aatatttata
     8221 gttcaactaa agcgtttata agaaattata caagagcatt aaatgttgaa cttaagagta
     8281 aagggataaa tgcaattgct gtatgtccag gttggatgag tacaaatcta tttaagagag
     8341 gtatagttgt agctgaaaaa gggacaaaaa atttcccagg tatagtgtct ccagacattg
     8401 ttgccaaaaa agcattgaag gatgcaaaga aaaataagga tatttctgtg tatggtataa
     8461 atacaaaatc cagtcattta ttagcaaaac tattgccaca aaaaatgatg atgaaggttt
     8521 ggttaatgca acaacatatt aaggaataag agtttcggta attaagtatc agttggagat
     8581 tcaatctgtt atatattatg agaagttttg ttgagcaaat aataattgtg acaaaacggc
     8641 ttatctagtg ccgataagcc gtctataatg tatataaaat atatttttga ttttacttta
     8701 tttagatatt gaagtattaa aatatgtagg acttgaaatt ttataaagat aaatactatg
     8761 atattttgta aaaactgaga tatgttgata ttacatagtt taactatact gttaaattga
     8821 agttttctta ttttgcatta tgcttattac ttaatgattt agactataat ttccatacca
     8881 tcatatgcaa aataaatgtt atcaagtttc ttttctaatt cactgtaata accatatgat
     8941 tttccccaca tttcgtcaat atgtgtaatg ataatctttt taattctata atagttttta
     9001 atttcaacaa tctcatctaa agtaaatatt tcatctttaa atggtgtgtc ttcaagcttt
     9061 gtaccatcat ttaatatacc atcatcagaa actagactta ttattaaaat atcagcatca
     9121 aagtacatat cactatgagt aaatggcttg ggattacagc aggcatatat gacttttttt
     9181 tcattctctt tgataacata gaaggttata ttcctgtctg ggttattgtt aatcaaatca
     9241 atatcaaaat tatttatctt tacatgcgaa gtttcattaa tagaaatgca atttataaca
     9301 tcaccataat atttaagaca atcgagattc gttcggttta tatcttcaat tacttcagga
     9361 agcgcataaa agccaattgg attattttct cctgtgataa agtcacatcc tattttttcg
     9421 acaattctaa tacccttaac atggtctggg tcatggtgag aaattgaaat atgttttact
     9481 tccgatattt tttgtctgtt acaagctact gcaatgtctt caggtgtgtc tatcagcatt
     9541 tttatatcat caatatataa acttggccct aatcgttcat atcttccgcc tttttgtctg
     9601 gcttcttcac atattttgca tttgcaaaat gaacttggaa taattgacat accgccacta
     9661 ccaacaattt ttaatttcaa agttattaca ccaccttctt aaaatattag attatataaa
     9721 taatatacaa gcacaactga ttaacaaaat tatgagttaa taaattatat cacatgcaaa
     9781 tatgaaagaa tagtatgaaa tttttataaa catatattaa atgtttctca atgaaattga
     9841 ctttgtatat gaactgaatg acttattcaa tatggataag acatttttct tgtaataaga
     9901 tatgattgtc ctataaggtt tatgtaattt tgatataatt tgatataata tattgattaa
     9961 caacatacat gttattggtg agcatatttc tatagaatgg aatatataat tttttacatt
    10021 tatcattgta ttattgtcta aagaaagtta aaaagagtag agcacaaagg aattatttgt
    10081 actttactct tttattgttt tgttaaaaaa actaatttat attagtgatt aaaatatatt
    10141 taactagagt ataaggatag tatataatct tataattgat ttatctgaca aattaagata
    10201 atatcctaat caaattctag tcatttaaac ataaaatcat aattgattta tctgacaaat
    10261 tgagataata tcctaattaa attgtaggta tttatacata acactaaaag taatttgttt
    10321 aacaaattaa gataatatcc taatcaaatt gtaggtattt atacataaca ctaaaagtaa
    10381 tttgtctaac aaattaaaat attatccaat taatataaaa attacttctt tttaactggg
    10441 aagcatacct ctgttaccca attatcagga ttactatcgt tgccaggact tacatgataa
    10501 atattaaaca taggaccatc cacatcatag ttattatctg atatccaatt accaatagcc
    10561 tcacaagcgt ctgcaacttg attgaaattt ccattaacaa ttgcagttgc agcagtcaca
    10621 cttggaacag tcttaaattt aacatgttca gtatctttat actttccaga tacagcaact
    10681 tgtacttcaa catctacata atcttcttta tatccagtat cataaaaaac tgctttagaa
    10741 tactttgggg gttcaatttg aacattctgg tcttttgtct ctaaaaatgc ttgatgccat
    10801 aacattcctt cgtcttgata agttggtata acccttctaa gtgtcatcat atattttggt
    10861 gcaaaattct ttatagttac atcataattt ttcataatat catttcctcc aattctttta
    10921 atagtggttt ctatttttaa tagttttttc tgtgtatctt ctaattgttc ttttacttga
    10981 gaatggtgga tatttagata ttttatgaga ctttctttat cgttatattc tgtcaaaatt
    11041 tcttttatag aatacaagcc aaagcccata tcttttagtg catggattct gtttgtagta
    11101 gaaagttggt ctgcactata gtatctatat ccattagttt tattcgtatg agaaggagtt
    11161 aaaagtccta tttcatcata atgacgtaac atacgaatac taattttact tagctttgaa
    11221 aaatcgccta tcttaaacat gtttttgtct cctttataaa ggtactttta gcttaatatt
    11281 aatataaacc atatcataat gttagagtca actaaaatta taattaaatt atattgacat
    11341 atgatgaaaa aaatattata ctgaacatgt tcagaaccaa aaatgttaat tgttttggag
    11401 gtctattatg aaaagtaatg ataaagatgc tagagaacgt ataattgaag ttacattgaa
    11461 tcttttaaat gaagtagatg atattgagga gattacagtt agaaaaattg ctgagcgtgc
    11521 aaatgttgga gttggtttaa taaattatca ttttaaaaca aaggataatt tgttgagtac
    11581 tgccatagga gatgtgatgt caaatataat agcagagcta tatgacgata gtgtatatac
    11641 tctaagacct attgaagatt tgaaaaattt attaaaaaaa ttgtgtgata ctggattaca
    11701 ttatgaaaaa gtgcttcctt ttgtgttgaa tcaatgtata accaatggag atatgcaagc
    11761 agaacttgat attgtcccta tgcttcgtaa aatttttgga aataaaaaag atgaaatgag
    11821 tctaagaatc attgccctgc aaattatttt accaatacag atttctgctt tatctacaga
    11881 atcatttcag ttatacagtg gtataaatat aaagaataaa tatgagcgag ataaattcat
    11941 tgatatttta atagaaaata ttattggaga ggatgttgat gtaagatgaa aattataact
    12001 attggttcaa gtcttatcac tgttttactt tttctttcaa ctatggtttg tgggttctgg
    12061 attaagaata ataaggtaac agatgcaagt tctattaagt tccatatgaa tagtgctatt
    12121 tttacaggga tatttttatt gatttccaca atccttttaa ttatatatat aaaaaaataa
    12181 taatattatt gataaataaa gtatcagaaa ttataaagac aagagtctta aaaatttctg
    12241 atactttacc atataatttt attaaacatt aattgtgtgt gaaaaaatat cacttatttc
    12301 aatctaatac taaatcttaa gagtgagtat aaagtattag aaattaagaa gcatttttta
    12361 gttcaagcgg attatctata ccaaaataat catataaagt agagcttatt tcctctaaat
    12421 ttccattttg gaaaggtaat tgtaaattta ccttttctac cacatcttta aatccagcat
    12481 cagtattttg atttaaaaaa tccatatata catcaacagc ttttctgtaa tcttcttgtg
    12541 ataattgcca tatctgaagt gatacatcag atgcaagacc ataactcaag taataaaaag
    12601 gaacttggaa gttatgagat acaagtatcc aaaaaggagc atttttttct ctaagtatat
    12661 tattggaaac tccatattct tcctctaaat caaaaaacaa tttattgata tcatttagac
    12721 tcatatatgg attcttgtat ataatttctt gaaattcatc ataaagacaa gcatcaataa
    12781 tagtatttaa aacaatcgat aagtgttctt tttttatagc ttcagattgt ttaccaaaaa
    12841 aatcatcaaa atatttataa aatagaattt ctaaagatgt tgaatgaact tcacatacat
    12901 ctatacttgg ttgcatctta ttatttaagt taatactgtt gtagtaatta taaaaatgac
    12961 caaactcatg agcaaaacta gtaacaccta aaaaagaatt gtcccatgta ttaaacaaga
    13021 aaggtgcttt atatttattt atataagtag tatatcctcc aggtgatttg ttttttccag
    13081 aagaataatc gtacaagtca tattttttca tatagtcgaa gctctctttt agttttggag
    13141 atatatcttc aagtacttta tcaaacttcc taaaagagcg atttttatat actttaatat
    13201 aaatagaaga atcagatggt ttagatgaaa tctctctata taatggaact atgtaatctt
    13261 ttacatcttg tctaaatttt ttagcttctt cttgagaata gtctttgttt aggttcatat
    13321 aggcataatc tatataattc ttaaaccctt gcttacttgc tatttcagtt cttgtctgta
    13381 taagttctaa gaatatgtta ccaaatatag gattgtattt ttttaagtaa tctgaataaa
    13441 ttttcacata ttcttcaggg ctaagatttg gtcttgacaa ggcttcttca aagtctacct
    13501 ctataccatc tattgatact gtagatttag ctaataagtc ttcatatttt acaactaggt
    13561 cttgctcttt tttaagcaaa ccttcaactt ctttagaatt aagttttcca atgttcttta
    13621 gataattaaa tgtatcattt ccaagttctt tttctaattc tttagagaat ttagaagtta
    13681 caaatctatc ttgaaagtct ttgtatgaca tgtcaacatc tactgattta ctcataagat
    13741 acttatattc cttagagtaa aattcgtctg acgaatctat gttatttcta atttttgcta
    13801 tagtaagtgt actgtaaaaa tcctgataaa ttttatcaac ttcattaaat aaatttaatt
    13861 gttccttagc tgttttagct gttaaaagtt tgtcgttaca tttgttaatg ttttcgcaaa
    13921 ttgactgtat attaggacgc ttatattcca ttttttcaaa aggaatagtt cctctaacag
    13981 aatctttttt tgtatcatta gtataatttc ttatgtatga tgcaaatata ataaaaactg
    14041 caattaaaat tagaaaaaca aatattttct tcttggattt aaccataaaa atcctccaat
    14101 catggatata gttattaatt attttactat attaaatata aaaaatgcat gttaagaaaa
    14161 tttaacataa agatatagat aagattataa ataatataaa aaatttaact tcaaaaaagt
    14221 atatgaaatt tatactggta aaatgataaa taaattttaa gtacaaaata gtaaaagcta
    14281 tgatagtttt agacctatta tatgtaaaaa atatagatgt ttttggtgca atttaaatta
    14341 aaagatatat ataaaaattt aaaatattcc aaacagaaat tataaaaatt actatcattg
    14401 tctttataca atatttatac tataatagaa taataattta gaggaaagct ctaaaaataa
    14461 acaaattaag ggtcttaaca gtagtgattt tatgttaagg aggtataaag aaagttgaaa
    14521 acaatagtta gaagacttat tctctacgca gatggaatgc gtcctactca aataatggta
    14581 tctgggtttg ctgcgattat tgtaatcgga gcattgttgt taacactccc gatagcgtcg
    14641 cagagtggag agagtatagg cttattaaat gctctattta cggctacttc agcggtttgt
    14701 gttactggtc tagttatggt agatacagca acttattgga gtttatttgg acagatagtt
    14761 ataataacat tgatacaaat tggtggtctt ggatttatga ccgtagccac aatgttttca
    14821 cttatggcac gaaaaaaaat acaactaaga gaaagattat taatacaaga gtcattaaat
    14881 caagctgatt tatcgggact tgtaagactt acaagatttg tattaataat aaccataaca
    14941 atagagggaa taggtgcact ggttttatca actgtcttta ttccacaatt tggtttgtct
    15001 aaagggatat ggtatagtgt atttcacgca atatcagcgt tttgtaatgc cggatttgac
    15061 ttgatgggca gtgtaagtgg cccatttaca tcgttaaatt cttatgtaaa caactttaca
    15121 gtatcaatga ctgtttgcgc acttatagtg cttggagggc taggattccc tgttgtactt
    15181 gatattgtaa gaaaaagaag attttcaaaa ttaaatgtgc attctaaggt tgtattgttt
    15241 tcaactgcta cacttatttt tgtgggtgca ttatttattt ttcttataga atttaatcaa
    15301 aaagctacta tggcggactt gcctttaaag ggaaaagtac tatcagcaat atttcaatca
    15361 gtaacagcaa gaactgctgg ttttaatacg cttgatttag ctactttacg agaaagtagt
    15421 gtatttgtaa tgataatttt gatgtttatt ggagcatcac ctgcatcaac tggtgggggt
    15481 ataaaaacaa caacactagc tgttttaatc attacagtta gaagttttct atcaggaaaa
    15541 tcagatatag aagcttttga aagaagatta gctccatcaa ctataaaaaa atctcttggt
    15601 atatttgtaa tcagtatatc agcagttatt tttggaacat tgattatttc aataactcag
    15661 cctaatttta cattagttca atcagctttt gaggttacat cagcacttgc tacagttggt
    15721 tcaagtttag ctggaactcc aaacttaaat gctttaggta agattataat aataatcttt
    15781 atgtttatgg gtagagttgg ttctcttact ttatttatgg ctatactttc tggtggtaga
    15841 agaaagagtc aaccaatcag atatgcagaa ggtaaaatta tggttggtta agttaccaag
    15901 gagtaatata aatttataat ggatttagag tagtactgta aatctgttga taaaataaat
    15961 gagcctagat gtaattatat gaagaaataa aatcgactaa tgaacaaaat taattaatga
    16021 aataaaaaaa cagggaaata aaatacaaat aaaaaggtaa atcaaaatta aattaatctg
    16081 tgtatataaa attatatatt gtgtataagt tttgtatgtg taaagtatat aagttttgta
    16141 tgtgtaaaca attaatttaa gagatattat ataaattgtg tattagggag gaagtttcga
    16201 gatgaagcaa tatatagtca ttgggtgtgg gagatttgga agttcagttg cgtctactat
    16261 gcatctttta ggacatcaag taatggcaat agacaaaaat gaagattcag ttcaaagtat
    16321 atctgacaag gtaacccatt cacttatagt ggatgttact gatgagcaag cgttaaggtc
    16381 attaggttta ggtaactttg atgtagcagt agttgcaata ggttctgata taagggcatc
    16441 tataatggcg actcttatag ccaaagaaat gggtgtagag ttgataatat gtaaggcaaa
    16501 ggatgaatta caagctaaag ttctttataa aattggcgca gatagagttg tatttccaga
    16561 aagagatatg ggagtaagag ttgcacacaa tttagtttcg gataatatat tagaccatat
    16621 tgaacttgac ccagagtatt caattgttga aatcgtaact ccaaatagtt gggttggcaa
    16681 gacacttata gagcttgaat taagagctag atatgagata actgtacttg ctataaaaac
    16741 aggtaaaaat ataaatgtta caccttctcc agatgaggaa cttacagccg gaagtatcct
    16801 agttataatc ggtcaaaata ctagtataac agcgataaca tctggaaata aggggataat
    16861 tagaagaaga taatttacta tttaatatat atttaattgc aatgaaagta gatagtatca
    16921 tataattatg aatagttata tgatactatt tttttaatcg aaggtagtat ttatttgtaa
    16981 gattagataa agagaagtta aattaaaagt aaggaggctg tgctaatata aaaatttata
    17041 agttattagc atttagataa aatgattaca aatataaaca gtaaggataa tgaaaagtta
    17101 aagtatacaa gagcactatt aaaatcaaag aataggaata aagagtcaaa gttcataata
    17161 gagggataca gaatagtaat gcttgcactt gaatgtatgg caaaccttga ttatgtattt
    17221 atcaatgaag aatttgaaaa taagaaagaa catgtaaaac tattagaaga tttggataaa
    17281 aaaaacacaa agatatacaa gactactaat aaaaacttta aagaattagt ggatacagaa
    17341 aatactcaag gaataatagg tgtagtttca tttaagaaaa aaaaattaag tgaaagtata
    17401 aataaaaaag ataaatttgt attgatttta gacagaatac aagacccagg aaatatgggg
    17461 actataataa ggactgctga ttctgctgga gtagatgcca taatagcact aaagggatgt
    17521 gtcgatatat acaacccaaa agtaattagg tctactatgg gttctatttt tgatattaat
    17581 ataattgatg cttcacaaga tgaaactgtg gacatgctta aatcattgga ttttaatata
    17641 gtttcaagtt acttaaatac agaaaatttt tatgacaaaa tagattatgg ctcaaaagta
    17701 gcattggtga taggaaacga agcaaatgga ataaatgaag aacttgtatc aaagtctgat
    17761 attttggtta agatacctat atatggtaaa gccgagtcgt taaatgctgc gataagctct
    17821 gctatactga tgtatgaaat aaaaaaatac ttaatttaat gtattgtaat aaatataatg
    17881 tcatgttata atcttgaatt aaatagtaga gtatcaaaaa tagtcaatat atattaaaaa
    17941 aataattaaa ttaattatat attagatgta tattatataa aaaataattg agttagttat
    18001 gc
//
LOCUS       DAEPUT010000084        17763 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.086, whole genome shotgun sequence.
ACCESSION   DAEPUT010000084 DAEPUT010000000
VERSION     DAEPUT010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17763
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.086"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..78)
                     /locus_tag="KRL22_003051"
     CDS             complement(<1..78)
                     /locus_tag="KRL22_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH1273500.1"
                     /translation="MWVLLKDFLLVSMGMGIGVVLMCILN"
     gene            complement(91..1287)
                     /locus_tag="KRL22_003052"
     CDS             complement(91..1287)
                     /locus_tag="KRL22_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1273501.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASGITREYLNKIESGK
                     MKPSKELLETLHKELVRFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LIDGGVMKRIDLAINDHTCILDIPELAEKCRKREYIGKSRSYKFYQSGELIKHREDDR
                     EYMGRTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFVDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEQQAKLTEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(1534..1938)
                     /locus_tag="KRL22_003053"
     CDS             complement(1534..1938)
                     /locus_tag="KRL22_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273502.1"
                     /translation="MGYLQMQLMNETTETITIGICLNIDKFYADLDFTANSDFEKWDE
                     YPIERFHEKMRVILEEMENKQQELPLLFSIPLDEEMSFLNITFCYNFIVMDKALFLHT
                     QHEFELDSEALEVCRNEDIGCVVLYLGMNTVM"
     gene            complement(1949..3328)
                     /locus_tag="KRL22_003054"
     CDS             complement(1949..3328)
                     /locus_tag="KRL22_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1273503.1"
                     /translation="MRKIWNKGHRIRASDKHLVYHFSIGTLLFVFVAVLLLLNINQLM
                     RTDWEHFSLLENGLTLSPYNFITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLAQM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGRLAQDRQ
                     VMPEQQEKE"
     gene            complement(3417..3812)
                     /locus_tag="KRL22_003055"
     CDS             complement(3417..3812)
                     /locus_tag="KRL22_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009265990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273504.1"
                     /translation="MLKEQDIKQYLNEKGSTFKENTSIIGVIFPSKFTYTLGPVATAL
                     SMQYYALNFSDSGIAIIGLNNVTGKLENDAFLFVLKEEITSVKFNKKLMSYELEISTS
                     KGTLAFKVNKTMVGASWHKENLATILKSL"
     gene            complement(4081..4605)
                     /locus_tag="KRL22_003056"
     CDS             complement(4081..4605)
                     /locus_tag="KRL22_003056"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273505.1"
                     /translation="MIYEPEKLKNKRTMYKKKDKMIVSIEFLLWAIILFAYVNIVIPY
                     VKSTIAFLTIIIGGIAIITAVYFFIAVYVLINRGHRFRKINNAIVREYHENKNGELFL
                     EKLFEIEEKPTDMNDEITWYLNIATAFSVLGKKNESISLLKQLEEVVTGKDKEYIQNS
                     IKFVKEQSEKDDTH"
     gene            complement(4602..5192)
                     /locus_tag="KRL22_003057"
     CDS             complement(4602..5192)
                     /locus_tag="KRL22_003057"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273506.1"
                     /translation="MAIIIYILTILLAVATFFIIKNKRYKVVPLVSWVIIIFFIGCVF
                     ISIVSLLVPYGEIFVLPLGSIVLGFVVILAAFNDFYSLIRCKDKIEGIYRGYNTYYGG
                     NGVSTQAPVFEYMYNGTKYNEQTTQNISYKLLTQNMRNGETYSIYVDPKHPAVFILQK
                     KIKVSSIITLIFGIMFFTAGIATLCAIFPVFWSVIK"
     gene            complement(5228..6040)
                     /locus_tag="KRL22_003058"
     CDS             complement(5228..6040)
                     /locus_tag="KRL22_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004221639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5037 domain-containing protein"
                     /protein_id="HBH1273507.1"
                     /translation="MRYKKFLLGVIASVLCLELLNGCGHKNEISIKIETYLQEEYGEE
                     FEVLSWKQQKLLPSDNGAIHATCISKNDPKHPFEGSYFNPEEPNSKIEIIDDGYAERL
                     LAKQMESMTEEAISQVAENYYIQGAIIIPEEWQDIPVEEISQWKNYVDLCNQSNSDYK
                     TLGSVWVYIDASTMTGKTDEEEYQMYEEVFRDKLGGQALLYVYYLDHKRFEKAEEILE
                     ISAPHKEGSNFEDIIEGQPYFGTIMRYGSDKFDDSLEIFKAAKQGQEQEIFQ"
     gene            complement(6155..6397)
                     /locus_tag="KRL22_003059"
     CDS             complement(6155..6397)
                     /locus_tag="KRL22_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004221655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273508.1"
                     /translation="MNIKEAIKMIQDEKLQGYNMNERKDDRENEVVLMRENDKWIVYA
                     TDERASKVTNSQDIYLDEEEALDDFIDRLRAFNRLR"
     gene            complement(6505..6888)
                     /locus_tag="KRL22_003060"
     CDS             complement(6505..6888)
                     /locus_tag="KRL22_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1273509.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNAGNPQNHTPQGQPKK"
     gene            complement(6904..7230)
                     /locus_tag="KRL22_003061"
     CDS             complement(6904..7230)
                     /locus_tag="KRL22_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1273510.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPVFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVADDI
                     VAVEEK"
     gene            complement(7469..10513)
                     /locus_tag="KRL22_003062"
     CDS             complement(7469..10513)
                     /locus_tag="KRL22_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH1273511.1"
                     /translation="MKKTWKRLCTGFLALATVVTALPTTPVHAESKQYWTESAERVGI
                     IEKVMNDGSIGSTFNEGYMKVEGETAYCIDINTDFKNGYKTRADASSRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFSGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITDGNG
                     NYSIAGATYGVFADKDCTKQLATLTTDENGNTDIAEVKAGTVYIKELSAPAGYKVDKT
                     VYSLKVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKDNPQGNASLAGAEFTWKYYA
                     GFYNKGNLPAEATRTWVTKTIAETHSDGTTHYITKLADTYKVSGDSFYMQDGKAVLPL
                     GTLTVEETKAPNGYLLEGAYMQAGDKSEQIKGLYLTQITEDGDLAVLSGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNDNSVLVEGKLYKKNEVVKTIR
                     TDIEGVASTSSDLLPYGKFRIVESEAPDGYLTDGAKPIDFTITENGKIVDLTDKAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGENHVVVTDDNGQFSTSADWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGFELIPPFEIVVSRN
                     NLVVDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEVTIVDTVKLNGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFVADEEEMKVEISYTFNASALGGKNLVTFEELYD
                     FSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKNGNKELEAGKDVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENAELLINGKRVESDYTFTADSETMKVEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDKGQTITFKEKPEEPEKPETPPTPEKPN
                     RPSDSPKTGDSTNVMAFIVMLLASAGGLAGTYLYKRRKMKKS"
     gene            10675..11481
                     /locus_tag="KRL22_003063"
                     /pseudo
     CDS             10675..11481
                     /locus_tag="KRL22_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008705947.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            11465..12235
                     /locus_tag="KRL22_003064"
     CDS             11465..12235
                     /locus_tag="KRL22_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273512.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            12245..13027
                     /locus_tag="KRL22_003065"
     CDS             12245..13027
                     /locus_tag="KRL22_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273513.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVNSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            13404..13940
                     /locus_tag="KRL22_003066"
     CDS             13404..13940
                     /locus_tag="KRL22_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH1273514.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            13972..14361
                     /locus_tag="KRL22_003067"
     CDS             13972..14361
                     /locus_tag="KRL22_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH1273515.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            14398..14784
                     /locus_tag="KRL22_003068"
     CDS             14398..14784
                     /locus_tag="KRL22_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HBH1273516.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            14911..16353
                     /locus_tag="KRL22_003069"
     CDS             14911..16353
                     /locus_tag="KRL22_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH1273517.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            16650..17465
                     /locus_tag="KRL22_003070"
     CDS             16650..17465
                     /locus_tag="KRL22_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1273518.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         5432 a         3205 c         3101 g         6025 t
ORIGIN      
        1 attcaaaata cacatcaaga ctacgccgat acccattccc atagatacca acaggaagtc
       61 ttttaataat acccacattt tttatcactc ctaactttcc accaaatctt ttgcaggggt
      121 cgtctgctgt ttgattatca tttcatgctt ttctgtgagc tttgcctgct gttcgattgt
      181 ttccatgtag tctgtaccgt ttcccttatc aatctttttc agcattttca aggttggtgc
      241 tacctgcctt tgtacccacc gcaatgtacg gtctaaggtg taaggttctg gctttgtcgt
      301 cagcttcaag ctctgtctgt tatcgccaat aaaccaagcc cagcggtcat tgagtttcca
      361 gtcatttttt cgcttgtctg gttcttcatc aacaaaccgc acatactggt tgatgataga
      421 aaaggcggtc tgttctgcgt cataataagt cagcaaatct cgtactgcat aataggcacg
      481 ttcatttcta agccgtatct caaaacgatt gataatgtcg gcttcttcaa gcggtgtccc
      541 taacttgacg tactgctcat agtccttttc atagatacag aaatacacat ctgatttcag
      601 cgaaccaaga taaagggtac gccccatata ttctctgtcg tcctctctgt gcttgataag
      661 ctcgcccgac tggtaaaact tatagcttct ggactttccg atatattccc gtttcctgca
      721 tttttccgca agctctggaa tatccaaaat gcacgtatgg tcgttgatag caaggtcgat
      781 acgcttcatc acgccaccgt ctatgagtgc gtccataaga aagtcatacc agcttctttg
      841 ctgtgccagc aggtaacttt caaactgcct acaaccacgc ccttttaatt ctaaaaggac
      901 acctttttct tcgtcagccg acgtatagat aaagatgtcc cctaaagaat aatgctccgt
      961 ataactgtaa tgtccgtaat cttcatggag catataattg atattcaatt ttaatatatc
     1021 tttgatgatg tgctgtatat ccagcgtggg aaaacgaatt ttcacataat caaacagcat
     1081 ggtaagtggt gcttctggat tgaaccttac cagttcttta tgcagagttt ccagaagttc
     1141 ttttgacggc ttcatttttc cgctttctat cttgttgaga tattctcttg tgataccaga
     1201 agccaccgcc agtctgcctt gtgagatacc gtaagcaatc cgtttctccc gtaattcttt
     1261 tatccattgt tcttcattca gaaccatacc cccaatctgt caagtgtgaa gttttttaag
     1321 gcgacttcac agccgatttt tgctagaaaa tcatgccaga agccttatgt ttcctatgtt
     1381 ttttgtctat tgtctatttg caaacgtacc cctctgttag ataccgaggg gttttacctg
     1441 ctggcgtggc tgacgccaca ccagcaacgg ctagtccgtg ccgtcgcctt tcgcttcgca
     1501 cgtcgccgtc ccgtcctgcc ttgcggtatg agcctacata acagtattca taccgagata
     1561 cagcacaaca cagcctatat cttcattcct gcatacttct aaggcttcgc tatcaagttc
     1621 aaattcatgt tgtgtatgca gaaacaaggc tttatccatg acaatgaaat tgtagcaaaa
     1681 tgtaatattt aggaatgaca tttcttcgtc cagaggaata gaaaataaca gcggtaattc
     1741 ctgctgtttg ttttccattt cttctaaaat tactctcatt ttttcatgga aacgctcaat
     1801 agggtattcg tcccattttt caaagtcgct atttgccgta aaatctaaat cagcataaaa
     1861 tttatcaatg tttaagcaaa taccgattgt aattgtttct gttgtttcat tcattagttg
     1921 catttgtaaa taacccatag ttattctttc actccttttc ttgttgttct ggcataactt
     1981 gtctgtcttg tgcaagtctg ccgatagtct gtaaaaaatc atgtcctttc gggactaaag
     2041 gcgtgtaaaa ttcactgata acgcttgttc ccacatcaca atagccacgt cccttgatac
     2101 gcttctgaaa aaactgtttt ttcacatctg aaccgaacag cataccgtaa cctagttcgc
     2161 tgatacgccc caatcccaca cgaaaattga agttatctct gataccgtcc gagaaatact
     2221 ttgcgtctgg acgctggcag gcaacgataa ggaaatatcc tgcttgtcgt cctaacataa
     2281 cgattttctt taactggcta agtaagctca cgctttcttt cgtccccagc atttcaaaaa
     2341 atgccacata ttcatcaaag ataagaaagc agggtggcag tcccagatag gcgtagtttt
     2401 cgccagtctt atagttcggg tgtcgcttca tttcctcact tcgctgtacc atgccctcat
     2461 aaaaggcatt gacgcaatct atcatttctt ctttggtgtg atatacattt cccataactg
     2521 ttcctaagtc cgcaaggtca gcgttcttcg ggtctaagat ataaaggaca gcgtttgtat
     2581 gcagtaaggc ttcaataagc gtcagcaaaa aataagtttt accgccacca gtcccaccag
     2641 caatcagagc gtgaggaagt gcgtcatatt cccagacaag atttttcatc agtctaagac
     2701 agccgttttc tgcccgtact tcatcaatgg taatgcggtt cgctatcata tcataaagca
     2761 gggtatattc gatatagccg tcatgcaggg tcttgtcggt cagctcacaa tacaagccac
     2821 tttccaattt atcctctaac cgtaaaagct ggtcttgata ttttcctaat gtaatttcac
     2881 agcggatatg aagcagtccc ttttccattt gataataaat ctttggaaac cagacgattt
     2941 tttcccttga tctgctttgc aggtcagtaa aaaaaccgct gtcttgtacg gtgtccgctt
     3001 cataccactt gttttccagt atcatttgtg ccagcttttg acggtgcagg agcttcttga
     3061 aactgtcgta acagaagcgg taatacagaa aagcgactaa tgcacaaaca ccagtcgcta
     3121 tcagtatggt tatgaaattg taaggggaga gcgtcaagcc gttttctaac aagctgaaat
     3181 gctcccagtc ggtacgcatg agctggttga tattcaatag caatagaacc gccacgaata
     3241 caaacagaag cgtccctatg gaaaaatgat agacaaggtg tttgtcgctg gctctgatac
     3301 ggtgtccttt gttccaaatc ttacgcataa atcaatcact cctttctggg tatgaaaaaa
     3361 gcagtcaatc ctaagactaa ctgctttata tgtatagata tgaatttttg aaaaacttat
     3421 aaactcttta aaattgtagc taaattttct ttatgccatg aagcacccac cattgttttg
     3481 ttcactttaa aagccaatgt tccttttgat gtactaattt ctaattcata agacattaac
     3541 tttttgttga atttaacact tgttatttct tcctttagca cgaaaagaaa cgcatcattt
     3601 tcgagttttc cagttacatt atttaaaccg ataatagcaa taccactatc gctaaaattc
     3661 aatgcgtaat attgcattga aagagcagtt gcaactggac cgagagtata tgtaaactta
     3721 ctagggaaga taacaccaat aatagatgta ttctccttaa aggtactacc tttctcgttg
     3781 aggtattgtt taatgtcttg ttcttttagc attttaattt tcctcctata aaattatttt
     3841 tcgcataact tactgtttac attttatcat ttcaatatag tgattacaat gtaaatatta
     3901 tatctaattt gcgattatcc gcataaacac tatactttta agcattttga aatataagaa
     3961 aatactcatt ttaccacgaa tttaccacga ttgaatgagc cttgatatga cactaaaaat
     4021 aacatgggag atggtacaaa atctggctat ctcccgtctt tcttaatttt attgtaacgc
     4081 ttaatgagta tcgtcttttt ctgattgttc tttcacaaat ttgatactat tttgaatata
     4141 ttctttatct tttccagtta caacttcttc taattgtttc aataaagaaa tgctttcatt
     4201 tttcttacct aatacgctaa atgcggttgc aatattaaga taccatgtta tttcatcatt
     4261 catatcggta ggtttttctt ctatttcaaa taatttttct aagaaaagtt ctccgttttt
     4321 attctcatga tattctctta caatagcatt atttattttt ctaaagcgat gtcctctgtt
     4381 tattaaaaca taaacagcaa taaaaaaata aacagctgta attatagcaa ttcctccaat
     4441 tataatagtt aaaaaggcga ttgttgattt cacataagga attactatgt tcacataagc
     4501 aaataaaatt atagcccata ataaaaattc gatagaaaca atcattttat cctttttctt
     4561 atacatagtt ctcttatttt ttaatttttc tggttcataa atcatttaat cacactccaa
     4621 aacacaggga aaattgcaca tagtgtagca atgccagctg taaaaaacat aattccaaat
     4681 ataagtgtaa ttatagagct cactttaatc tttttttgga gaataaatac tgctggatgc
     4741 ttcggatcaa catagatact gtaagtttct ccattcctca tattttgcgt taaaagctta
     4801 tatgaaatat tttgtgttgt ctgttcgtta tactttgttc cattatacat atattcaaaa
     4861 acaggtgctt gggtagaaac tccattccct ccgtaatagg tgttatagcc acgataaata
     4921 ccttctatct tatctttaca tcttattaaa gaataaaaat cgttaaacgc agctaagata
     4981 actacaaacc ccaagacaat acttcctaaa ggtaatacaa atatttctcc atatggaacc
     5041 aataaagata ctatcgaaat aaatacgcat ccaataaaaa atataataat aacccaacta
     5101 acaagcggta caactttata gcgtttattc ttaataataa agaatgttgc aactgctaac
     5161 aatatcgtta gtatataaat aatgattgcc atatccgttt tcccaatacc ctttctttca
     5221 atcttactta ctgaaatatt tcttgttctt gaccttgttt tgcagccttg aatatctcta
     5281 agctatcatc aaacttatct gaaccatatc gcatgattgt tccgaagtat ggctgacctt
     5341 cgataatatc ttcaaaatta ctgccctctt tatgcggtgc tgaaatttcc aatatttctt
     5401 ctgctttttc aaatctctta tggtctaaat agtaaacata aagcaatgcc tgaccaccta
     5461 atttatcacg aaagacttct tcatacattt gatattcttc ttcatcagtt tttccagtca
     5521 ttgtagaagc atcaatatag acccaaaccg aacctaaagt tttataatcc gaattacttt
     5581 gattacatag atcaacataa tttttccatt gtgaaatttc ctccactggg atgtcttgcc
     5641 attcttcagg tataataata gcaccttgaa tataatagtt ctcagctacc tgcgaaatgg
     5701 cttcttctgt catagactcc atttgttttg ccaaaagacg ttccgcatag ccatcatcaa
     5761 taatttctat ttttgagttt ggttcttcgg gattaaaata gctaccctca aatggatgct
     5821 ttgggtcatt ttttgaaata caagtcgcat ggattgcacc attatctgat ggtaaaagtt
     5881 tttgttgttt ccaagacaac acttcaaatt cttctccata ttcttcttgt aagtaggttt
     5941 caatttttat tgaaatctcg tttttatgtc cacagccatt caatagctct aaacaaagca
     6001 cacttgctat aacgcctaat aaaaattttt tatatcgcat aatcgccacc tctatgtgat
     6061 tttatgattt aacacagttc tacaaactgg aagttgtcta tttaaaagaa aattactaaa
     6121 tatctttttt gaggtcattt taattctccc atagctacct taatctatta aaagctctta
     6181 atctatcaat aaaatcatct aaggcttctt cctcatctaa ataaatatct tgtgaatttg
     6241 taaccttact agcccgttca tctgttgcat aaacaatcca cttatcattc tcacgcatta
     6301 acacaacttc attttctcta tcatctttcc tttcattcat attataacct tgtaatttct
     6361 cgtcctgtat catttttatt gcttctttta tgttcatgtt tcatgctcct atttttgtac
     6421 tacaacttct aatttgtccg tttcttcata tccatattat aacagttcca tatatccgct
     6481 acaattaaaa tctattcagc aagcctattt cttcggctgt ccttgcggtg tatggttctg
     6541 tggattgcct gcgttctggt tgcctttatt cttcaataca atatcctctg cctttacata
     6601 ccagtccaca tctgcacccg tataggtctt tcttgatacc gtatcggcta ctggattgac
     6661 aagctccacg actgcattgt acggaaattc ccttaacggt acttctggcg gtacggacac
     6721 ggggataatg ccaccatgca gactgcactt caaatcatag atacgttttt ttagctgggt
     6781 actcggtgtc ccgtcctcat tctgcaagaa tacatcacgc accgctgtaa attttaattc
     6841 tccaaatgtt ttttctttgt caataacaaa cccgtttgat aatctcataa attcttcact
     6901 cctttacttt tcttcaactg ctacaatatc atcagcaact aacacataat cggtatgtcc
     6961 catatccccg attgcgtaac ctctgccgta taacttcgga ttgacaagtt ttactttctg
     7021 ctcatacttg aaatgctttt cgccagcctg cacgggaatt tctaccacaa cattttcgcc
     7081 tttctgtacg tcagaataaa ggttatagct tcgtctggct aaaaccctgc ggttattttt
     7141 atctctttca aagactggct cactttcgcc tgcaaattca agagttccaa aagactgtgc
     7201 catatctggc acgacatatt tcatttccat attgttttac ctcgtttctt tctatatttg
     7261 ataagtttat tgattgtgat ttcttattct ggcggtttgg gaagtaccag caatccccca
     7321 gatagtaaag ggtaaaatca atgcttacgc acccttgact atccgtgttc ttgcaggttg
     7381 ctggcagaca agccagaata agcaaaagtc tgccgtttga cagcttcggc ggagagcgtg
     7441 atttttcttt catcataccg ttaccgcctt atgatttctt cattttacgg cgtttgtaaa
     7501 gatatgttcc agccaatcca ccagcagacg caagcaacat cacgataaat gccattacat
     7561 ttgtactgtc gcccgttttg ggactgtcgc taggtctgtt aggcttttct ggtgtcggtg
     7621 gtgtttcggg tttctctggt tcttctggct tttccttaaa ggtaattgtc tgtcccttat
     7681 cctcaatatc cttatgctcg gtaactttct tcggttcgtc tggattgctc aaatcgtaca
     7741 attcttcaaa agttacaagc tgtttaccgt caagagaagt agcatcaaag gtaaaggcaa
     7801 cttccacttt catagtttcg ctgtcagcgg taaacgtata atcactttcc acacgctttc
     7861 cattgataag aagttctgca ttttcttctt tcaacatctg ccagcccaca agtttgtact
     7921 gtgtaccgac ttctaagccc tctaaggtta cggtatcaat gattgtaacg tcttttccag
     7981 cttcaagctc tttgttgccg ttcttatccg tagcagtcgt atgaattttg atgatacgct
     8041 ctgtgataag taccgtctgt ccgtcgtcct caatgtcttt gtgttctgca actttcacgg
     8101 gttcgtctgg attgctgaaa tcatacaatt cttcaaaggt aacaaggttt ttgccaccta
     8161 aagcagacgc attgaatgta taggaaattt ccactttcat ttcttcctca tcagcgacaa
     8221 aggtataatc gttttctaca cgtttcccgt caatgataag ctcggcgttt tcttccttta
     8281 acatctgcca gcctttgagc tgatactttg tgccttttgt aagtccgttt aatttgacag
     8341 tatcaacaat cgtaacctct tttcctgcaa ggatagtctt ttcgccgtcc ttgctggtcg
     8401 ctgtggtatg gatagagatt tctttttcgt attcatcagt caaagtccct aaatcaacca
     8461 caaggttatt tcttgatacc acgatttcaa aaggtgggat aagttcaaag cctttgttac
     8521 tatcagagcg taattcttca atgatgtaag tatcgtaagg taacgcacct ttgctgtcgt
     8581 ctggttcaga agttccaaac cacacaccgt cctcgctggt cttgcctgcg tttgtattgt
     8641 gcttatgaga agcccagtca gcagaagtgg aaaactgccc gttatcatca gttaccacta
     8701 catgattttc gcccgttgtc ttgcttgtga tccgaaaggg aacatcagca agacgcttgt
     8761 gtgtacctgc accgattttc acgccctcaa tatctccacg cttaatctga ttgtagatag
     8821 aatgggcttt gtcggttaag tccacgattt ttccattttc tgtgattgta aaatcaatcg
     8881 gttttgcacc gtcagttaag taaccgtcgg gagcttcact ttcaacgata cgaaattttc
     8941 cataaggtaa aaggtcagaa gaagtagaag cgacaccctc aatatcggta cgaattgtct
     9001 ttaccacttc atttttctta tatagcttgc cctcaaccaa aacagaatta tcatttaagg
     9061 aaatgatgtc aaaggcagta tctttcaagg ttgcacttcc ttgtggcttt gtatcgcccg
     9121 tttctaaatc tcgtttctga atttttacac cgccacggat aaccttgtct gatacggaaa
     9181 actggttact tccagatagt acggcaaggt cgccgtcctc ggtaatctgt gtaaggtata
     9241 agccttttat ctgttcggac ttatcgccag cctgcatata tgcaccctct aacaagtagc
     9301 cgtttggagc ttttgtttct tcaacggtta gtgtcccaag tggaagaacg gcttttccgt
     9361 cttgcatata gaagctgtcg ccagatactt tgtatgtgtc cgctaatttt gtgatgtaat
     9421 gagttgtccc atcgctgtgt gtttcagcga ttgtctttgt aacccatgta cgagtagctt
     9481 cggcagggag attgcctttg ttatagaagc ctgcataata cttccatgta aattccgcac
     9541 ctgctaaaga agcgtttccc tgcggattgt ctttctgtgt ttccatatca atcttgaaaa
     9601 gctcaatcaa agtgtccgtt actttcggtg tatctgatac tttcaaagtc gctgtctttc
     9661 cagcttcaac ctttaaggaa tatacagttt tatctacttt atatcctgct ggtgcggata
     9721 attccttgat atagactgtg cctgctttta cctctgcaat atctgtattt ccgttttcat
     9781 cagtcgtaag ggtggcaagc tgtttcgtgc agtccttatc agcaaagaca ccgtatgtcg
     9841 caccagcgat agagtaattc ccgttaccgt ctgtaatgct ggtattactg gaagtctttt
     9901 gtaatttcgc atttccgaca ttcagtttcg cccagaattg tcccaattcc tgcccctcgc
     9961 cagagtagat ataaccgcca cattcatagc gtcctttatt ttctttgaca aaggcttttg
    10021 caccagagaa aacttcgtcc tgcgttgcct ttggaatttc atcataagaa gctcgcacgt
    10081 tatcacattg ccagccaaga tgtacgctca atctctgcca aactacacat tgttccaaca
    10141 gatagacttg tttatagttc aattccttgt gagcttcgcc atactgtttg acatactcta
    10201 aggataacgc cacatctgaa atctggtcgg cactcatgcg tgagcttgcg tcagctctgg
    10261 tcttgtagcc gttcttaaaa tctgtattga tgtcaataca ataggcagtt tcgccctcga
    10321 ctttcatata gccctcattg aatgtcgaac cgatagaacc gtcattcatt actttttcaa
    10381 tgataccgac acgctctgca ctttccgtcc agtattgctt gctttctgca tgaacgggtg
    10441 tagtcggtaa agcagtaacg acagttgcaa gagctaagaa gcccgtacac aatcgtttcc
    10501 atgtcttttt cataaatcta atgctccttt ctgtaatcat cacaatttaa aaacgccact
    10561 tgtgaagtac aaatgacgtt ttaggtgtga taatgacttt tctttatctt tcttattttt
    10621 aatttttcct ttatttatgc ggtttttccg ctttgtctat ataagcatgt accgaacggt
    10681 gcgggtaaga cgacaactat gaaaatgtta ttgggtctaa caaaaccaac tactggagaa
    10741 attaaaatat ttggtcagga cattcacaat aacgagaaga agcttcttcc tcgaattgga
    10801 tgtttgattg aatcaccagg gttttatcct aatctgacag gaacagaaaa tctcaaaatc
    10861 tttgcaaggc ttagaggaat accaaaaaaa aatgcagtag aatcagcact ggatgtagtc
    10921 ggtttgccaa acaatgacaa aaagttattt tctcaatact ctcttggtat gaaacagagg
    10981 ttggcgattg ctcttgccat tatgcatgac ccacaactgt tgattttgga cgagcctatc
    11041 aatggacttg atcctattgg tattgcagaa gtaagaacgt ttattcgtga tctctgcaca
    11101 gaacgaggta aaactatttt gatttccagt cacattcttt ctgaaattgc cttgttggca
    11161 gatgacattg gcattattga ccatggtatt ttgttggagg aagaaagtct tgcccaatta
    11221 gaagaaaaaa acagtaaata catacatttt gctgtatctg atgcagcaca ggcagcaagg
    11281 cttctggaaa cccaacttaa cctgaaaaat ttcaaagtag cagataatta caatattatg
    11341 ctatatgata cagatgtttc tgttgcagaa ataaatcgtg ctttcattct aaacaacatt
    11401 gaggtatcag aatctcattt atgcgaagat actcttgaag attacttcaa gaaagtaaca
    11461 gggggtgaag gaattgcttg atataatttc atgtgaattt tcaaaactca agcggttaaa
    11521 atttatactg atttctattt taggtgcttg cttatttcca attcccgcaa caattttgat
    11581 tgcaaaggac aacttgccct ttgagcaatt gttcaaatta gttgtcaatt ttggatattt
    11641 tttgctatta ccaattgtat taagtattgt tgctagccaa ctatttttta tagaaagaga
    11701 taatgatgta ttaaaaaatc ttgcaacagt gccagtgcaa aaaggaaaac tggctctggc
    11761 aaaattggct gtgttgctgt ttatatcatt gttctactct gttgcagggt taggagctac
    11821 tatcattgga ggtttcattg ttggaatagt agagggggtt gctgtaaaat taggaatgag
    11881 cattgctttt ggaattatgt tttttgttac tgtacttcct gttgtggtac tcattgtata
    11941 tttcaatcgt agctatattt tttctattat actttctttt gtatatgcta ttttcaattt
    12001 tagtatatcc ttaaatatta tcaattttga accaaataac ccaatattaa gtgtattacc
    12061 tgctcctgtt ataatgcgtt ggtggatggc attttgggga gatcccactg gcgaatacac
    12121 ggcacttaga cagccatatt tgctctcaac tcctgcttgt gtaggtattt tatgtttgat
    12181 aaccattata gcagtcctgc tgatttgtat gatatacaaa aagcaggaga attaggaggt
    12241 atctatgctt gatataatta ctacagaatt tcaaaaaata aaaagatata atattctatg
    12301 gattggtgtt gttgctgttc tgttttcagc actattggca gtttttcagg ttgtaaattc
    12361 acatggcagt gaccctctaa cgtatgagag ctttgcaaac ggagttatct ggaataattt
    12421 cagtcttagt tttccatttg ggattacact tattggagga tatcttatta accgtgaata
    12481 tacagaccaa accttaaaaa acatcctaac tgttcctatt tcattacgca aattgctagt
    12541 gggaaaatta attgcggttg gaggaattac tgtattgtta agtcttttca gcttcttatg
    12601 cacatttatt ttggggttgt tattttgcaa tatcaatata tctgttacac tcgttgtaaa
    12661 atccttagtt cagattttgt ctgttaatct gtactgttat gttgctgttt tgccgattat
    12721 tgcttatttt ggtcgtaaac aaaatgcatt tctgacgggt gtagggattg catttgtata
    12781 cggtttttgt ggtgtgtttg ttgctggaag aaatctgaca gacttttatc caatcacagc
    12841 aggtcttggt ctagttggat acaacaatgg tgctggtact gtttatcagc cacttatcgg
    12901 tgctatgact ttgattgtaa ttctaatctt gacaactatt ctacttgtat ttacacctaa
    12961 ttatgataaa gttatgacca tatctaagaa aaaagggata aagcataaaa agtattctca
    13021 taaataacat aaatattgtt tctattattt aagttgctag acagtgaaaa gaaaaaatct
    13081 gtcgtacagt ggctatatgc tcatgtattc aagaagctac agttttgatt tttcataact
    13141 gtagcttctt tttgtattta ttaaatcacg actatcataa tacttgcaat aggtatagta
    13201 acaagagaga gtactgtcat atgtgtttta tatattacat taagtatatt ctaaaatata
    13261 tgttttaaat aatatatttg aaaataggaa tatttaaata aaaaaaataa tattatatat
    13321 agttgacaaa aattggaaaa tgagatacta tataaatata gaaatagtaa tcattactat
    13381 tattaaaaag ggaggaatta attatgaact taaaaggaac taaaacagaa aagaatttaa
    13441 tggcaggatt tgcaggagag tcagaagcaa gaaataaata tacatactac gcttcaaaag
    13501 caagaaaaga aggttataat caaatagctg ctatatttga agaaactgct aacaatgaaa
    13561 aggaacatgc taaattatgg tttaaacttt tacatgatgg tatgccttca acagaggaaa
    13621 atttaaagga tgcagcagca ggtgaaaact atgaatggac tgatatgtat gcaaaatttg
    13681 ctaaagaagc tagagaagaa ggatttgaca agatagctta tttatttgaa gctgttggaa
    13741 aaatagagaa agagcatgaa gaaagatact taaagctttt agaaaactta aatgaaggaa
    13801 aaatatttaa aagagatgaa gaagttgttt ggcaatgtca aaactgtggt catgtgtatg
    13861 taggtactga agcaccagaa aaatgcccag tatgtgacca tccaaaagca tatttcaata
    13921 taaaagctga aaattattaa aaattatcat tattaaaaag gaatgttaac tatgaaattt
    13981 tctaaacaac gagaactgat tttaaatgaa atattaaata atccggttca tcctactgcg
    14041 gattacctat atgaaaactt aaaaaaagat aatccaaatt taagcttagg aactgtgtat
    14101 agaaatttag ctcagctaac ggaacatggc tttataagaa aggttagtat tccagggtat
    14161 ccagatagat ttgatggtcg aatagataat cactatcata tcatatgtga agtatgtgga
    14221 gaggtatacg atttagaatc cgaagttctt aataatttac aagaattaat atctgaggag
    14281 acagacataa aaataacatc ttataacata agttttaaag ggatttgtaa taattgtaaa
    14341 aggtgtagcc aagtaggtta gttttcaaat tctaaaaata attaatgagg tgagtttatg
    14401 tgtagtgaac aaaaattttt tatatgtgag acttgtggaa accttgtagg aatgatacaa
    14461 agtggtggtg tacctatttt ctgttgtgga aaacctatga aggaacttgt tcctaataca
    14521 acagatgcag cagttgaaaa acatgtacct gtaattgaag tggatggaaa taatgttact
    14581 gttaaagtaa gtagcacaac tcatccaatg actaaagaac atcatatagc atgggtgtat
    14641 cttatgactg aacaaggtgg tcaacgcaaa tgtctagcag tagatggaga acctgtagtt
    14701 aaatttgctt tgaatgatga tgataaagtg atttctgcct atgcttactg taatttacat
    14761 ggattatgga aggctgaact gtaatattta aataaattga gtcaaaaagg aggctataaa
    14821 tgtattttca tacaaatagc ctcctataaa tttatataaa ttcaagtttt aattttgttt
    14881 aatgtcaata taatataagg agaaaataat atgtcaattt ataaatgtag tgtttgtgga
    14941 tatatttatg atgaatctaa gaatgataaa acatgggatg aattaagtga agattgggaa
    15001 tgccctgtat gtacaaaagg tcgtagttat tttggaaaga taagtactgt ttactatgaa
    15061 gaagatgaaa agatagcaga agacatagtt gaagatgaat ctaaattaaa tactgaaaaa
    15121 gagggagatt taaattactt aagtacatat ttaagaagag atgatgaagt tgagaaacat
    15181 atggatataa ttcacgaaat ggctgttaca ggaaaatcta taatagaacc tatgagaact
    15241 aaactaccag taatttcttg ggatgatatt ttaattatgg gtgctcaatt aaatccatta
    15301 cctttaaatg agcatgatga agtaaataca acaacaataa taggaaaaaa agcaaagaaa
    15361 cctatgatta tagaaaatcc agtttatatt tcccacatgt catttggagc tttgtctaaa
    15421 gaactaaaaa tagctttagc aaagggggca gcccaaaata agacagctat gtgtagtggt
    15481 gaaggaggta tattaccaga agagaaggaa gcttcataca agtatatttt tgagtatgta
    15541 ccaaataaat atagtgtaac tgaagaaaat cttaaaaatt ctgatgctat agagataaaa
    15601 attggtcaag gaacaaaacc tggtatggga ggtcatcttc ctggcgaaaa agtaactgaa
    15661 gaaatagcaa aagtaagaaa taagcctgta ggtcaagatg taataagtcc ttcttgtttt
    15721 gaggaaatac aatccaaaga ggatttaaag aaacttgtag atgaacttag agaagtttca
    15781 gaagggcgtc caataggtgt taaaatttca gcaggtcata ttgaaaaaga tatggaattt
    15841 atagcttatg ctaaacctga ttttgtaact attgatggtc gtggtggagc tactggagca
    15901 agtccaaagt tgcttaaaga tgcaacttca attccaacaa tatttgctct ttatcgtgct
    15961 agaaaataca tagatacaca tggattagat atagatttgg ttataacagg tgggcttcgt
    16021 atatctactg attttgctaa ggcaattgct atgggggctg atgcagttgc tattgcaagt
    16081 tctgctctta tggcagcggc gtgtcaacaa tatcgtatat gtggttctgg taagtgtcct
    16141 gtaggagtag ctactcagga tgaggaattg agaaaaagat tacatataga aaatagtgct
    16201 aatagagtgg caaacttttt aaatgtaagt ttagaagaac ttaagacttt tgctagaatt
    16261 tctggtcata aagatataca tgatttaagt gttgatgatt tatatactgt taactctgaa
    16321 atatcaaatt atacaaacat acagcatgta tagattgaag tttgaaatta ttagatttta
    16381 gacagctata aaagtaaatg ataaatatat tttataaaag agagtgtctt aaaatgaact
    16441 ttttagttca taagtcactc ttttttgtat gaagccaaat atatttatca ttttagcaat
    16501 gaaaaagaat cttatctctt tattttgaga tagactcctt ctatttatga aaattaaaga
    16561 tattaaattg taaaatattc tgtgatgtcg tactattaaa ctaaagattc tgtactttaa
    16621 agtaaataaa aatttaagga gtgattatta tggaaagatt gaagatacaa gttttagttg
    16681 acaataatac ttatattgat agatactttg ttggagaacc agcagtaagc tattatattg
    16741 agattgatgg aaataggatt ttgtttgact cagggtattc agatgtattc atatcaaacg
    16801 ctgaaaaatt aaatatagat ttaggaaatt taactcatgt tgttttttct catgggcata
    16861 atgaccatac aagaggtatc cagtttttag aaaataggta tgatttatct acagttgaac
    16921 ttatttcaca tcctaactgt tttataccta gaaaacatgg agagaaaagc ataggagctc
    16981 cattttctgc tgaggaaatt aaaaatattt ttatgtataa tcctaaggat aagccattta
    17041 atctaagcaa gaattgtgtg tttttaggtg aaataccttc tataaatgat tttgaaaaaa
    17101 gagctaaaat tggtaaatgt aaaataggag atttgtggga agatgattat gttttagatg
    17161 attctgctat agtttgtaaa actgataaag gtatttttat tgttacagga tgttctcata
    17221 gtggaatttg taatatagta gagtatgcta aaaaggtatg tggagatgat agagttattg
    17281 gtatactagg tggttttcat ctttttgaat tgaataatag gttagatagt acaatacaat
    17341 atttggataa agaagaaata agaatgttgt acccttgtca ctgtgtttct tttaaggtaa
    17401 aagcgaagat gaatgaaata ttgaatataa atgaagttgg agtagggctg accataagta
    17461 tatagtattt gaaagtatat aagatttaag ttgaaggtta aaaagatatt ttctatagaa
    17521 aatatctttt ttgttacgtt tattttaaga gaaatcaata tacttttata tgaaatattg
    17581 taaaaaaatt tatttttaat gagaatatat tttcattaat aaacaatttt attatgtatt
    17641 aataatgtta gaataaatat aaataaatca aagttactta cattacagta tattttttca
    17701 caaaatatat tgatttattc ttttaaagtt tgataattcc aatgaatgta ataaaagaag
    17761 gaa
//
LOCUS       DAEPUT010000085        17660 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.087, whole genome shotgun sequence.
ACCESSION   DAEPUT010000085 DAEPUT010000000
VERSION     DAEPUT010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17660
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.087"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            110..463
                     /locus_tag="KRL22_003071"
     CDS             110..463
                     /locus_tag="KRL22_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273519.1"
                     /translation="MAKRPVEKYDFKAFGEAIKAAQTGRKESRKQVSDEMYISPRYLA
                     NIENKGQHPSLQIFFELMLRYNISVDQFLLDTPAPKDTKRRQLDALLDNMSDNGIRIV
                     TATAKEISEVEKEDK"
     gene            712..1041
                     /gene="mobC"
                     /locus_tag="KRL22_003072"
     CDS             712..1041
                     /gene="mobC"
                     /locus_tag="KRL22_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBH1273520.1"
                     /translation="MNGRKRKIQIKFYVTEEERALIEQKMKLVPTRNMAAYLRKIAID
                     GYIIQTDHSDIKAMTAEIQKIGVNINQIAKRVNATGSVYQEDIEEIKGVLAEIWRLQR
                     LSLLKAR"
     gene            1002..2351
                     /locus_tag="KRL22_003073"
     CDS             1002..2351
                     /locus_tag="KRL22_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBH1273521.1"
                     /translation="MAVTKIKPIKSTLSKALDYIQNPDKTDGKMLVSSFGCSYETADI
                     EFGFTLAQAIEKGNNLAHHLIQSFEPGEVDYEKAHEIGKQLADAVTKGQHEYVLTTHI
                     DKGHIHNHIIFCAVNFVDYHKYNSNKRSYYGIRNMSDKLCRENGLSVVVPGKGSKGKS
                     YAEYQAEKVGASWKGKLKITVDTLIPQVASFEELLQRLQAAGYEIKPGKYISCRAPGQ
                     ERFTRLKTLGADYTEEAIKERIEGKRTKAAKAPKEQRGVSLLIDIENSIKAAQSRGYE
                     QWAKIHNLKLAAKTMNFLTEHKIEQYADLVSRIEEVNAENEKTADALKSVEKRLANMA
                     VLMKHVTTYQKTKPVYEAYRRAKDKDAYRAKQESSLILHEAAAKALKTAGVSKLPNVA
                     ALQVDYEKLREQKEALYADYGKLKKQVKEYDVIKQNIDSILRQPREPEREKGKERGE"
     gene            2444..2674
                     /locus_tag="KRL22_003074"
     CDS             2444..2674
                     /locus_tag="KRL22_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273522.1"
                     /translation="MEQEMPDYETICAAVVGEKWALEKVLDCYGDEINRLAMVKKCQP
                     DGTIKEEIDEDLRQTLIMKLLEAIPQFPMEKE"
     gene            3058..3477
                     /locus_tag="KRL22_003075"
     CDS             3058..3477
                     /locus_tag="KRL22_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015522580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH1273523.1"
                     /translation="MNERERIIHLWFDMWLKQQDLGIDSIFTEDVIYTESWSPKYESR
                     KTVKHWFDEWNTRGKVLVWDIKQFFHKENQTIVEWYFKNKMNNGNIEEFDGISLIVWT
                     ENNKIMELKEFGCNLNTYNPYAQNDMPQFRDEKTKWF"
     gene            complement(3655..4020)
                     /locus_tag="KRL22_003076"
     CDS             complement(3655..4020)
                     /locus_tag="KRL22_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBH1273524.1"
                     /translation="MTGLKRLTPPQSRKVNSLVKKECCNCDNGHCILLDDGEECVCPQ
                     LISYSLLCKWFQTAVLPLDKLLYAELFKTEDKKRCTECGASFASTSNNVKYCPDCRKR
                     ITRRQAAERMRKRRALVTQ"
     gene            complement(4017..4223)
                     /locus_tag="KRL22_003077"
     CDS             complement(4017..4223)
                     /locus_tag="KRL22_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBH1273525.1"
                     /translation="MIRLTVEETNLLSIYNEGGKRGLMENINAALPFMDEDMRELAKR
                     TLAKIAPLTENEYAELAIFAADEV"
     gene            complement(4226..8257)
                     /locus_tag="KRL22_003078"
     CDS             complement(4226..8257)
                     /locus_tag="KRL22_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1273526.1"
                     /translation="MASLRDTVKDYQEELRDGIAWVAFWKTGRSWNAEHFSLEMGDIL
                     YPEDRSRMEEIKQADPAAVVVNGYYSGYLGEDMSLDELTAGVRRHYENGYSNIGEFIE
                     AHDNRLPPELIEEARAAAHAAGLPFSEKAYRDGEEPDPYIFDGSMSMEDYELMHRMIE
                     NERSERMEETILSGYLSNLGKYTEGRPAGEWVSFPTTAEHLKEAFDRIGIDFKNYGEW
                     YFTEFQSSVPGLTTHLNEFSHPDELNYLSELLKMQFDDDREKFVAAMEYGDHTRDLQD
                     IINLAQNLDCYWLYPSIQCEEDYGHYLIEELDELELPEEAKKYFMYEEYGRDAAINDG
                     GSFTEQGYIYNNRNTFTEWYDGCEVPEEYRVTPQPPVQEKEQADLDTSVAIQTTATEQ
                     PPVLPIILSSEKPADKMKEITDRLEQGILGLYESDRYADYLRTMSKFHDYSLNNTILI
                     AMQGGNLVKGYKQWEKEFDRHVKPGEKAIKILAPSPFTVKKQVEKIDPDTQKPVFDKD
                     GKPVTEEREIKIPAFRVVSVFDISQTEGKELPALTYELTGNVEQYKDFFAALEKTFPF
                     AMGFEALSGGVKGRCNYEEKRIIINEGMDELQNIKTAIHEIAHATLHDTALAMPERPD
                     RRTREVQAESVAYAVCQHYGLDTSDYSFGYIAGWSSGKELAELKGSLETIRSTAASLI
                     DTIDGHFAEIQKTQNKEQTTEQAQPAQETAKQPETEIAAPELPEEKAPAKEQDGQPEQ
                     TTQTAAPYYTINEAAAKRAKDMNSFSDYKQGSATAEYRHYVDEAVQIAERQKQRVDPM
                     YHEKIDSLLDTYARKLAANMNKGYEIDARVPSILIAGGSNFPTRKKEKQNAARDSNYR
                     EWQDIQGLLDKIRSTGMGGISADDPQAVQKLEKKLESLEKSQETMKAVNAYYRKHKTL
                     DGCPHLPPEELEKLKADMASSWHLEDKPFATWALSNNSAEIRRVKDRIKSLSQQKEIG
                     FVGWEFDGGKVEANTEANRLQIFFEDKPDETTREALKSNGFRWSPKAGAWQRQLTSNA
                     YYAADYVKAIAPLTGEKPTELQWAHIRAQKVAAQEQPAQEQPEQEAPQDKDTFSIYQI
                     KGEEETRDLRFEPYDRLTATGHRVDPKNYALVYSAELTPGTSLEDIYTRFNIDHPKDF
                     KGHSLSVSDVVVLHQNGQDTAHYVDSFGYKEVLEFFKEQEKALIPDDLETGETIKTPR
                     GTFYVTAMSREQMEAAGYGLHHQSDDGKYLIMGNGTRAFAVPVQPENYLKAAEQTTEQ
                     NYNMIDGQINNTPTTAELEAKVKAGETISLVDLAEAVKADKERGKAAKTEKKPSIRAQ
                     LRADKEKTAQKKAAKSKNHELEV"
     gene            complement(8390..10480)
                     /locus_tag="KRL22_003079"
     CDS             complement(8390..10480)
                     /locus_tag="KRL22_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBH1273527.1"
                     /translation="MILVIAEKPSVAQTIAAVLGVKEKKDGFLTGSGYIVSWCVGHLV
                     GLAEAAAYGEQYKKWNYDSLPILPQEWKYTVAADKEKQFKTLKELMHRADVSEVVNAC
                     DAGREGELIFRFVYEMAGCKKPMRRLWISSMEDSAIKEGFSRLKNGKEYDALFASALC
                     RAKADWLIGINATRLFSVLYNHTLNVGRVQTPTLKMLVDRDAAITTFKKEKYYHVRLA
                     LSGAEAASERISNKAEADALKTTCEASKAVCTSLLKEKKTAAPPKLFDLTSLQREANR
                     LFGYTAKQTLDLAQALYEKRLLTYPRTDSSYLTDDMGDTAAGIIKLLCGKFPFMAGKD
                     FTPELAKVLNSKKVSDHHAIIPTMELAKTDLAALPESERNILTLAGARLIMATAAPHT
                     FEAVTAVFECAGQSFTARGKTVLSDGWKEIDRKYRAILKSKPETDDADSDTEKTLPPF
                     TEGQNFDNPAAKVTEHDTTPPKPHNEASLLSAMERAGSEDTDPDAERKGLGTPATRAA
                     VIEKLVKGGFVERKGKQLLPTKDGINLVCVLPDTLTSPQLTAEWENNLTQIAKGKADP
                     AAFMKGIEDMARELVKTYPFLSEADKGRFKEEKPELGKCPRCGSPVYEGKKNYYCSNK
                     ECSFTMWKNDRFFEERKVTFTPKIAAALLKSGKVNVKKLYSPKTGKTYDGTIALADTG
                     EKYVNYRIELSKKK"
     gene            complement(10497..10685)
                     /locus_tag="KRL22_003080"
     CDS             complement(10497..10685)
                     /locus_tag="KRL22_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273528.1"
                     /translation="MTLFTDNPFEKMMIQKPNGRRDNAPPVPYPPACASCPYKGQSPC
                     VGYCLKQVQKKKETEPER"
     gene            complement(10682..11410)
                     /locus_tag="KRL22_003081"
     CDS             complement(10682..11410)
                     /locus_tag="KRL22_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBH1273529.1"
                     /translation="MKNKLKKTMTALCAALILIGGFSVPAYAQGAATEQPAGDATNDS
                     NVVVEEKEETPPLTPKGNATLVDDYGGNKQLITVTTKSGNYFYILIDRAAEGEQTVHF
                     LNQVDEADLMALTENGEAAKKPEICNCTEKCEAGKVNTSCLVCVTSMTSCTGKEPTPT
                     PTEQPEEPKEKGGNPGVVLALVLFALLGGGAAFYYFKFMKPKQNVKGDTDLEDFEFED
                     YDEDEPEADTGETPEDEETEEETL"
     gene            complement(11400..11669)
                     /locus_tag="KRL22_003082"
     CDS             complement(11400..11669)
                     /locus_tag="KRL22_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBH1273530.1"
                     /translation="MANNKIERINKEIAKTREKITEYQNKLKGLEAQKTEAENLEIVQ
                     LVRAMRLTPQELNAMLSGGGIPGMNAAPATETADYEEQEENADEE"
     gene            complement(11701..13680)
                     /locus_tag="KRL22_003083"
     CDS             complement(11701..13680)
                     /locus_tag="KRL22_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016292376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBH1273531.1"
                     /translation="MKQLKPRDKITQKMTRDGVVEVNETQQTAERISSREADGDFSQP
                     DSAAAERVIEHLDAAHTRKANKKAVKKEQEATALRTSTSRLQFTDEERATPELEPYIK
                     KSEKAADKLDAAKAAIPKQKKLVKERTFEEATGKAKTRLHFEEQEKPIPGGKKGNPLS
                     RPAQEAGIFVHNKIHSVEKDNSGVEGAHKSEELAERGAKYGARKLKQGYRSHKLKPYR
                     EAAKAEKAAFKANVNFQYHKTLHDNPQLTSNPLSRFMQKQQIKCQYAKAAKKGGAKAA
                     AEATRKTAKKTAEETRKAAAFAARHPAGVLIAVAALLLFIMISVGLSSCGAMFSGLTN
                     GVLGTSYTSEDSDLVAVENNYAALENGLQSEIDAIESTHPGYDEYRYDLDSIGHNPHE
                     LASYLTALLQSYTPQSAQAELERIFEKQYTLTLTEEVEIRYRTETSTDPETGETTTEE
                     VPYEYYILNVKLENKPISSFVSELLTPQQLEMFHVYLETSGNKPLIFGGGSPDGSPSE
                     DLSGVEFVNGTRPGNQELMELAKQQVGNVGGYPYWSWYGFNSRVEWCACFVSWCYNQA
                     GKSEPRFAGCEWQGVPWFQSRGQWGARGYENIAPGDAIFFDWDLDGVADHVGLVLGRD
                     GSRVYTVEGNSGDACKIKSYDLNYQCIKGYGLMNW"
     gene            complement(13668..14627)
                     /locus_tag="KRL22_003084"
     CDS             complement(13668..14627)
                     /locus_tag="KRL22_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBH1273532.1"
                     /translation="MKTDVIINRDALAALKELPSESVHCCVTSPPYYALRDYGLDAQI
                     GQEDTPKQYIDRLTAVFGELYRVLRKDGTLWLNIADTYCSTGNKGGYADPKNPKGRTG
                     QRVARNSRVTGCKQKDLIGIPWLLAFSLREQGWYLRSDIIWQKQNPMPESCKDRPTRC
                     YEHIFLLSKEKKYYYDAAAIAEPIAPTTAERYRRARSTNSKYTQEISGQGKVQGLNRP
                     RDGGYYDDALMPTTRNKRDVWLINTVPYKGAHFAAFPPKLAETCILAGCPKGGIVIDP
                     FFGSGTTGFAAKSLDRHYIGIELNAEYCALARARIGGAGLSSN"
     gene            complement(14624..17053)
                     /locus_tag="KRL22_003085"
     CDS             complement(14624..17053)
                     /locus_tag="KRL22_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1273533.1"
                     /translation="MSKGQTKKTREAAGNRRKLTRAEKKQIAEAIRKAKGDGKARTAQ
                     QTIPYLAMYPDGICKVTEKRYSKCVMFEDINYQLAQADDKTAIFENWCDFLNYFDASV
                     SVQLSFINQGTQREQAEKAISIPAQEDAFNSIRTEYSDMLKNQLSKGNNGLVKHKYIT
                     FTVEADNKAAAKSRLSRIETDVLNNFKVLGVTARPLSGYERLKVLHGVFHPEGEPFSF
                     SFDWLTPSGLTTKDFIAPSSFHFGEGRYFRMGKKIGAASFLEILAPELNDRMLADILD
                     LETGVIVNLHIRSIDQSEAIKTIKRKITDLDKMKIEEQKKAVRSGYDMDIIPSDLATF
                     GSEAKNLLQDLQSRNERMFLLTFLVVNMADTKRKLENDIFAAAGIAQKYNCRLTRLDY
                     QQEAGLLSSVPIGENLIPIQRGLTTSSTAIFIPFITQELFQTGQALYYGLNALSNNMI
                     LCDRKQLKNPNGLILGTPGSGKSFAAKREMTNAFLITDDDIIICDPEAEYFSLVQRLN
                     GQVIRLSPTGRGIDGKPQYVNPMDINLNYSEDDNPLALKSDFILSLCELVIGGKEGLQ
                     PVDKTVIDRAVRNVYRPFLADPDPAKMPILGDLYDELLRQPEPEAARIAAALELYVSG
                     SLNVFNHRTNVELNNRLVCFDIKQLGKQLKKLGMLIVQDQTWNRVTINRAEKKSTRYY
                     MDEFHLLLKEEQTAAYSVEIWKRFRKWGGIPTAITQNVKDLLASREVENIFENSDFVL
                     MLNQAQGDRTILAKQLNISPQQMKYVIHTEAGEGLIFYGNVVLPFVDRFPKDTELYRV
                     MTTKPEEVSSL"
     gene            complement(17001..17405)
                     /locus_tag="KRL22_003086"
     CDS             complement(17001..17405)
                     /locus_tag="KRL22_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBH1273534.1"
                     /translation="MAYVPVPKDLSKVKTKVAFNLTKRQIVCFAAALLIGLPLFFLLK
                     GSAGTNLAAMAMIVVMLPCFLLAMYEKHGQPLEVVVRNIIQTKFTRPKERPYRTENLY
                     AVLEKQRKLEKEVSAIVKRTNKKDAGSRRKQA"
     gene            complement(17427..>17660)
                     /locus_tag="KRL22_003087"
     CDS             complement(17427..>17660)
                     /locus_tag="KRL22_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273535.1"
                     /translation="NREWGQIGNNYLKGLFALGFQGFLIMICVGIYAVLVNDMIIADN
                     LHSAVFSLAAYTVILCFSLFKSGTLAKSIFNAH"
BASE COUNT         4031 a         4292 c         4388 g         4949 t
ORIGIN      
        1 acgaacaata gcaagtatat aaatatgaat tattatggct atttagtgga actgtataaa
       61 catatccaag gagaaagggg aacagtaaaa tgtaactggg tgaataaata tggcaaaaag
      121 accggtagaa aaatatgact tcaaggcatt tggagaagct ataaaagctg cgcagacggg
      181 gcgcaaagaa agccgcaaac aggtaagtga tgaaatgtat atttctcctc gctatcttgc
      241 aaatatcgaa aacaaaggac agcaccccag cctgcaaatc ttttttgagc ttatgcttcg
      301 ttacaatata tccgtagacc agtttctttt agatacgccc gccccaaaag atacaaagcg
      361 gcggcagctc gacgctctcc ttgataatat gagcgataat ggcatacgga ttgtaacggc
      421 aactgcaaaa gaaatttcag aagtcgaaaa agaggacaaa taaatgtgtc cggcaaattg
      481 aatatgattt aggaagcgtt gtaatcttta cagattgcag cgtttttctt ttgctctttt
      541 ttggcatata gagcattgcg ttgtagtaac cagtgaggaa aaaactttcg tagcaagcat
      601 aggaaaagag taccattttc cgtattttcg ccctcccgcc ctgcggtgcg tcggttgaaa
      661 attgcttgtt gggaagtgtc ccaaaccctc aaagcggaaa ggagcgattg catgaacgga
      721 cgcaaaagaa aaatacaaat caaattctat gtaacagagg aagaaagggc attgattgag
      781 cagaaaatga agctcgtccc cacccggaac atggcggcgt atcttcgcaa gattgccatt
      841 gacgggtata tcattcagac agaccatagc gacataaaag ccatgacagc ggagatacag
      901 aaaatcgggg tcaatatcaa tcagattgca aagcgtgtca acgcgacagg cagcgtctac
      961 caagaggaca tagaggaaat aaagggggtg cttgcggaga tatggcggtt acaaagatta
     1021 agcctattaa aagcacgttg agcaaagccc ttgactatat ccaaaacccg gataaaacag
     1081 acgggaaaat gcttgtgtcc tcttttgggt gcagctatga aacggcagat attgagtttg
     1141 gatttacgct tgcacaagcc atagagaaag ggaacaatct cgcccaccat ttgatacagt
     1201 cctttgagcc gggggaagtg gattatgaga aagcccacga aatcgggaaa cagcttgccg
     1261 acgcggtaac aaagggacag catgaatacg tcttaactac ccacatagac aaagggcata
     1321 tccataacca tatcattttt tgtgcggtca attttgttga ctaccacaaa tacaattcca
     1381 ataaacgcag ctactatggc atacggaaca tgagcgataa gctgtgccgg gaaaacgggc
     1441 tgtccgttgt cgttccgggt aagggcagca agggaaaaag ctatgcagaa tatcaagcgg
     1501 aaaaggtcgg tgcaagttgg aaaggcaagc tgaaaattac cgttgatacg cttatccccc
     1561 aagtggcaag ttttgaagaa ttgttgcagc ggttacaggc agcgggctat gagataaagc
     1621 cgggaaaata tatctcctgc cgcgctccgg gacaggaacg gtttacccgc ttaaaaaccc
     1681 tcggtgcaga ttatacagag gaagcaatca aagaacggat agagggcaag cgcacaaagg
     1741 cggcgaaagc tcccaaagag cagcgcggcg tatcgctgct tattgacatt gaaaacagta
     1801 tcaaggcagc gcagagccgg ggctatgaac agtgggcgaa aatccataat ctgaaactgg
     1861 ctgcaaagac tatgaatttc ttgacagaac ataagattga gcagtacgca gatttagtca
     1921 gccggattga ggaagtaaat gcggaaaatg aaaagacagc agacgcatta aagagcgtgg
     1981 agaaacgtct tgcaaacatg gcggtgctga tgaagcacgt taccacctac caaaagacaa
     2041 aacctgtcta tgaagcatac cgcagggcaa aggataagga cgcataccgg gcaaagcagg
     2101 aaagcagtct gatactccat gaagcagcgg caaaggcact aaaaacggcg ggcgtttcca
     2161 agctcccgaa tgtcgccgcg ctacaagtag actatgaaaa gctccgggaa cagaaagaag
     2221 ccctttacgc ggactatggc aaactgaaaa aacaggtcaa agagtacgac gttatcaaac
     2281 agaacataga cagcatttta cggcagccaa gagagccgga acgggaaaaa gggaaagaac
     2341 gcggggagta gctttgttca tacttgtgtg atataatagt tcctatcaaa gacagtagcc
     2401 acatactaaa gtgatacatt ttcagcaaag gaagtgtcag aaaatggaac aggaaatgcc
     2461 ggactatgaa acgatatgcg ctgccgttgt gggcgaaaaa tgggcgttgg aaaaggtgct
     2521 tgattgttac ggcgacgaaa tcaaccgcct tgcaatggta aaaaagtgtc agccggacgg
     2581 gactatcaaa gaggaaatcg acgaagattt acggcaaaca ctcataatga aactgttaga
     2641 agctatccca caatttccaa tggaaaagga gtgataccat gacacgcgga gaaatttgga
     2701 aagacttttt caagagaaac gttttgcccg ccgttattgc attgttttta ttcttcatgt
     2761 tcaagaacat ctttacagag gacgggtaga ccaattactt ttatgtatgg ctgtgctgcg
     2821 gtatcccctt tggcattcgc cgtatgttcg tatggcttgt accgcatgga tatgacatag
     2881 ctggaacggt gggtatcgtt gccattaact tcattttgga cggcattatc ggcgggggca
     2941 ttttaatatg gcggcttgtc gttgctacgt ggtatatccc ccttacgata taccgtttac
     3001 ttaccgcaga taagagtgca acccctcaaa tcaatataga gaaaggattt aaaagttatg
     3061 aatgaaagag aaagaattat tcatttatgg tttgatatgt ggctaaaaca acaagattta
     3121 gggattgata gtatttttac agaagatgtg atttacactg aaagttggag tcctaagtat
     3181 gaaagtcgaa aaacagtaaa acattggttt gatgaatgga atactcgtgg aaaagtctta
     3241 gtgtgggata ttaaacaatt ttttcataag gaaaatcaaa ctattgtaga atggtatttc
     3301 aaaaacaaaa tgaataatgg taatattgaa gaatttgacg gaatttcttt aatagtatgg
     3361 acggaaaata acaaaataat ggagttgaaa gaatttggtt gtaatctcaa tacctataat
     3421 ccatacgccc aaaatgatat gccacaattc agagatgaaa aaacaaagtg gttttgaagt
     3481 tttaaaagcc gggacgcaga cagtcggtaa agactatccg cgccccggct ttcttatggg
     3541 tacagcgata aaatgttacg cagtagaacg ccatttttga gggaaaaggt ataaaaccct
     3601 tgccgcgtca ttttcacacc cggaaagccc tgtaaatcaa ggcttttttt gcccctactg
     3661 cgtaacaagg gcgcgtcgtt tcctcatgcg ctccgctgcc tgtctgcggg taatacgctt
     3721 ccggcaatcc gggcagtatt tgacgttgtt agaggtggac gcaaaagaag ctccgcactc
     3781 ggtacaacgc tttttatcct cggtcttgaa aagctctgca tatagcagct tatcaagggg
     3841 aagtacggcg gtctgaaacc atttgcaaag aagcgaatag gaaataagct gcgggcagac
     3901 acattcctcc ccgtcgtcca gtaaaataca gtgtccgtta tcgcagttgc agcactcttt
     3961 ttttacaagg ctgttgactt tccggctttg gggcggcgta agccgcttta gcccggtcat
     4021 acctcatcag cggcgaaaat ggcaagctcc gcatactcat tttctgtcag aggtgcaatt
     4081 ttcgcaaggg tgcgcttcgc cagttcccgc atatcctcgt ccataaacgg cagcgcagcg
     4141 ttgatgttct ccataagccc gcgcttaccg ccctcattgt aaatgctcaa caggtttgtt
     4201 tcttcaacgg tcagtctaat catgctcata cctccaattc gtgatttttt gattttgccg
     4261 cttttttctg tgcggttttt tctttgtctg ctctaagctg cgcccggata gagggcttct
     4321 tttccgtttt tgctgccttg ccgcgttcct tgtcagcctt gacagcttcc gcaaggtcaa
     4381 caagggaaat ggtttctcct gcctttacct ttgcttccag ttctgcggta gtcggggtgt
     4441 tgtttatctg cccgtcaatc atgttgtagt tttgctctgt ggtctgctcg gcagctttca
     4501 gatagttctc cggctgaacg ggaacagcaa aagccctagt gccgtttccc ataatcagat
     4561 attttccgtc gtcggactgg tggtgcaatc catatccggc agcttccatt tgctcgcggc
     4621 tcatggcggt tacatagaaa gtccctctcg gtgttttgat tgtttcgccc gtttccaagt
     4681 cgtcgggaat gagggctttt tcctgctcct tgaaaaactc cagcacttcc ttataaccga
     4741 agctgtctac atagtgggcg gtgtcctgcc cgttctgatg aagcaccacc acgtcggaaa
     4801 cggaaaggct gtgtccctta aaatctttcg ggtggtcgat attgaagcgg gtgtaaatat
     4861 cttcaaggga agtccccggc gtaagctctg cggaatagac aagcgcatag tttttcgggt
     4921 ctacccggtg tcctgtggca gtcagacggt cgtaaggttc aaagcgcaag tcccttgttt
     4981 cttcctcgcc ttttatctga taaatggaaa aggtgtcttt gtcctgtggg gcttcctgtt
     5041 ccggctgctc ctgtgcgggt tgttcttgtg cagctacctt ttgcgcccgg atatgcgccc
     5101 actgtaactc ggtaggcttt tccccggtaa gaggtgcaat cgccttgaca taatcagccg
     5161 catagtaggc attactggta agctgccgct gccatgcccc tgcttttggc gaccaacgga
     5221 agccattact ttttaaggct tcccgcgtgg tttcgtccgg cttatcttca aagaagattt
     5281 gcagtcggtt cgcttcggtg tttgcttcca ccttaccgcc gtcaaattcc caacccacaa
     5341 aaccgatttc tttttgctgt gaaagggatt tgatacggtc tttcacgcgt cggatttctg
     5401 cgctgttgtt ggataacgcc caagtcgcaa agggcttgtc ctccaaatgc caactgctcg
     5461 ccatgtctgc tttcagtttt tccagttcct ccggcggtaa atgcgggcag ccgtcaaggg
     5521 tcttatgctt gcggtaatag gcgtttacgg ctttcatggt ttcctgtgat ttttcaaggc
     5581 tttccagttt cttttctaac ttctgtactg cctgtgggtc gtctgcgctg ataccgccca
     5641 tgccggtgct gcggatttta tcaagaagtc cttgtatgtc ctgccattcc cggtaattgc
     5701 tgtcgcgggc tgcgttctgc ttttctttct tccttgtggg gaagttagag ccgcccgcaa
     5761 tcaggataga gggaacacgc gcgtcaatct catagccttt gttcatgttc gccgccagtt
     5821 tccgggcgta ggtgtcaagc aggctgtcga ttttctcatg gtacatcggg tcaacccgtt
     5881 gtttctgcct ttctgcgatt tgtacggctt catcaacata atgcctgtat tcagccgtcg
     5941 cgctgccttg cttataatcg gaaaaactgt tcatatcctt tgcacgtttg gcggcagctt
     6001 cattgatagt gtaataaggg gcggcggtct gcgtggtctg ctccggctgt ccgtcttgct
     6061 cctttgcagg ggctttttct tcgggaagct ccggcgcggc tatttctgtt tcgggctgtt
     6121 tggcggtttc ctgtgcgggc tgcgcctgtt cggtggtctg ttccttattc tgtgtctttt
     6181 ggatttctgc aaaatgtccg tctatggtat caatcagact tgcggcggta ctgcggattg
     6241 tttcaagaga gcctttcagt tctgcaagtt cttttccgct gctccacccg gcgatatatc
     6301 caaaagaata atccgacgta tcaagcccgt aatgttggca gacagcatag gcgacgcttt
     6361 ccgcctgtac ctcgcgggtg cggcggtcgg ggcgttccgg catagcaagg gcggtatcat
     6421 gcagcgtggc gtgggcgatt tcatggattg cagtcttgat attctgcaat tcgtccatgc
     6481 cctcgttgat gatgatacgc ttttcctcat aattgcagcg tccttttacg ccgccgctta
     6541 gtgcttcaaa tcccatagca aaggggaaag tcttttcaag ggcagcgaaa aaatccttgt
     6601 attgttccac gttgcctgtc agctcatagg taagggcagg aagctccttt ccctcggtct
     6661 gtgaaatatc aaagacagat accacacgaa aagcgggtat cttgatttcc ctttcctcgg
     6721 taacaggttt cccgtcctta tcgaaaacag gcttttgggt gtccgggtcg attttttcca
     6781 cctgtttctt aacggtaaac ggggacggcg caagtatctt gatagctttt tctccgggct
     6841 ttacatggcg gtcaaattcc ttttcccatt gtttatagcc tttcacaaga ttgccgccct
     6901 gcatggcgat aaggattgta ttgttaaggc tgtaatcatg gaattttgac atggtacgca
     6961 gataatcggc gtaacggtcg ctttcataca gtcctaaaat tccttgttcc agtcggtcgg
     7021 taatctcttt cattttgtca gcgggctttt cagaagatag gataatcggg agaaccgggg
     7081 gctgctctgt ggcggtggtt tgtatggcta cggaagtgtc aaggtctgcc tgttcctttt
     7141 cctgtactgg cggctgcggc gttacccggt attcctccgg cacttcgcac ccgtcgtacc
     7201 attctgtaaa ggtgttgcgg ttgttgtaga tatagccctg ttcggtaaag ctgcccccgt
     7261 cattgatagc agcgtcccgc ccgtattcct catacatgaa atattttttt gcttcttcgg
     7321 gcaactccaa ctcgtccagt tcttcaatca gataatgccc gtaatcttcc tcacactgta
     7381 tggacggata aagccagtaa caatcaaggt tttgtgcaag gttgatgatg tcctgcaagt
     7441 cccttgtatg gtcgccgtat tccatagctg caacaaattt ttcccggtcg tcgtcaaact
     7501 gcattttcaa aagttcgctc aaatagttca gttcgtcggg gtgggaaaat tcgttaaggt
     7561 gtgttgttaa acccggaacg gaagattgaa attctgtaaa ataccattct ccatagttct
     7621 tgaagtctat cccgatacgg tcaaaggctt ctttcaaatg ctcggcagtc gtggggaatg
     7681 atacccattc gcccgcaggt ctgccctcgg tgtactttcc aagattagaa agatacccgc
     7741 ttaaaatcgt ttcttccatg cgttcactcc tttcgttttc aatcatacgg tgcataagtt
     7801 cgtagtcctc catgctcatg ctcccgtcaa aaatataggg gtcgggttct tcgccgtccc
     7861 ggtaggcttt ttcagagaaa ggcagccccg cagcgtgggc ggcggctctt gcttcctcga
     7921 taagctccgg cggcagcctg ttgtcgtggg cttcgataaa ttccccgata ttgctatatc
     7981 cgttttcgta gtggcggcgt accccggcgg tcagctcgtc aaggctcata tcctcgccaa
     8041 gatagccgga ataatagccg tttaccacaa cggcggcagg gtcagcctgc ttgatttctt
     8101 ccatgcggct tctgtcctcc gggtagagaa tatcgcccat ttcaagggaa aaatgctcgg
     8161 cgttccaaga acgtcccgtt ttccaaaacg ccacccaagc gataccgtcc cttaattctt
     8221 cttgatagtc ctttacggtg tcccgtaaac ttgccatgtg taacctcctt tcttcactgt
     8281 cttagagggt ttgggaaact tcccaacaag caaaaatccc cgccgttctc ggtagagaaa
     8341 gcagggattt tacggaaaag ggtactcttt tcctatgctt gctattcagt tatttcttct
     8401 tcgacagttc aatgcggtag ttgacatatt tctcgcctgt atcagccaat gcgatagttc
     8461 cgtcgtaagt tttgcctgtc tttggggaat agagcttctt cacatttacc ttgccggatt
     8521 ttaagagtgc agcggcaatc ttcggggtaa aggttacttt tcgttcttca aagaaacggt
     8581 catttttcca catggtaaag ctacattctt tgttgctgca atagtagttt ttctttccct
     8641 catagacagg agaaccacag cggggacatt tcccaagctc cggcttttcc tctttgaaac
     8701 gccccttgtc agcttcggaa agaaacggat aggtctttac cagttctcgc gccatatcct
     8761 cgataccctt cataaatgcg gcggggtctg ccttgccttt ggcaatctgc gtcagattgt
     8821 tttcccattc tgcggtaagc tgcgggcttg tcaaggtgtc cggcaggacg cacacaaggt
     8881 tgataccgtc ttttgtggga agtagctgct tgccttttcg ctccacaaag ccgcccttta
     8941 ccagtttttc aatgacggcg gcgcgggtgg cgggagttcc aagccctttg cgttctgcgt
     9001 ccgggtcggt gtcctcgctt ccggcgcgct ccatagcgga aaggagcgac gcttcattgt
     9061 ggggctttgg cggtgttgtg tcatgctccg ttacctttgc cgctggattg tcaaagttct
     9121 gtccctcggt aaacggcggc agggtctttt ctgtgtcgct gtctgcgtcg tccgtttcag
     9181 gcttactctt taagattgcc ctgtattttc ggtcaatctc tttccacccg tcggacagta
     9241 ccgtttttcc ccttgcggta aaggactgtc cggcacactc aaaaactgcc gtaaccgctt
     9301 caaaggtatg cggtgcggca gtcgccataa tcagacgcgc cccggcaagg gtaaggatat
     9361 tcctttcgct ttccggcagc gcggcaaggt cggtctttgc aagctccata gtcgggataa
     9421 tggcatggtg gtctgatacc tttttactgt tcagcacctt tgcaagctcc ggcgtgaagt
     9481 cttttcccgc cataaaagga aatttcccgc aaagcagctt gataatgccc gctgctgtgt
     9541 cgcccatgtc gtcagtcaga tagctgctgt ctgttctcgg ataagtaaga agtctttttt
     9601 catacagggc ttgtgcaagg tcaagggtct gctttgccgt atatccgaac aggcggtttg
     9661 cttccctctg taaagaagta aggtcaaaga gcttcggcgg ggctgcggtc tttttctctt
     9721 tcaaaaggga agtacagact gcttttgacg cttcgcaagt cgtttttaat gcgtcggctt
     9781 ctgccttatt tgaaattctt tcacttgcag cttccgcgcc ggataaggca aggcgcacat
     9841 ggtagtattt ttctttcttg aaagtggtaa tcgctgcgtc ccggtcaaca agcattttta
     9901 aggtcggggt ctgtacacgc cccacgttca aggtatgatt gtaaaggaca gagaaaaggc
     9961 gggtggcatt gataccgatt agccagtcag cctttgccct gcatagtgcg gaagcaaaga
    10021 gcgcgtcgta ttccttgccg ttcttcagac gggaaaagcc ctctttgatt gcgctgtcct
    10081 ccatagaaga aatccaaagg cggcgcatag gtttcttgca gcccgccatt tcatagacaa
    10141 agcggaaaat gagttctccc tcgcgccctg cgtcgcaggc attgacgact tcggaaacat
    10201 ctgcccggtg cataagctct tttagggttt taaattgctt ttccttgtcg gcagcaacgg
    10261 tgtatttcca ttcctgcggc aaaatcggta agctgtcata gttccacttt ttatactgtt
    10321 ccccgtaggc ggcagcttcc gcaagcccta ccaaatgtcc cacgcaccaa gaaacgatat
    10381 agccgcttcc tgtgagaaat ccgtctttct tttcctttac cccaagtacg gcggcgattg
    10441 tctgcgccac actgggtttt tctgcgataa ctaaaatcaa atataagttc ctcctttcag
    10501 cgttccggct cggtttcttt tttcttctgt acctgtttca gacagtaccc cacacaaggg
    10561 gactgtccct tgtaagggca ggaagcgcaa gccgggggat aaggaacagg cggcgcatta
    10621 tcacgccgcc cgttcggttt ctgtatcatc atcttttcaa agggattgtc ggtaaacagg
    10681 gtcatagggt ttcttcctcc gtttcttcat cttcgggagt ttccccggta tctgcttccg
    10741 gctcgtcctc gtcgtagtcc tcaaattcaa aatcttcaag gtcggtatcg ccctttacat
    10801 tctgcttcgg cttcataaac ttaaagtagt agaacgctgc gccgccacca agcagggcaa
    10861 agaggactaa ggcaagcacc acaccgggat tgccgccttt ttctttcggt tcttccggct
    10921 gctcggttgg tgttggggta ggttctttgc ctgtgcagct tgtcatactg gtaacacata
    10981 ccaggcagga cgtgtttacc tttccggctt cgcatttctc cgtacagttg cagatttccg
    11041 gctttttggc agcttcgccg ttttcggtca gtgccataag gtcggcttcg tccacttgat
    11101 ttaggaaatg tacggtctgt tcgccctcgg cggcgcggtc aatgaggata tagaaatagt
    11161 tgccgctttt ggtggtaaca gtgataagct gcttattgcc gccgtaatcg tcaaccagtg
    11221 ttgcgtttcc ctttggggta aggggcggcg tttcttcttt ttcctccaca actacgttgc
    11281 tgtcgttggt cgcgtccccg gcgggctgct ctgtggctgc gccctgtgca taggcaggga
    11341 cagaaaaacc gcctataagg ataagggcgg cacaaagggc ggtcatggtc tttttcagtt
    11401 tattcttcat ctgcattttc ctcctgttct tcgtagtctg ccgtttcggt agcgggtgcg
    11461 gcgttcatgc cgggaatacc gccgccggac agcatagcgt taagttcctg cggggtcagt
    11521 cgcatagctc gtacaagctg tacgatttca aggttttccg cttcggtttt ctgcgcttcc
    11581 agtcctttta acttgttctg atactctgtg attttctcgc gggtctttgc gatttcctta
    11641 ttgatacgtt cgattttatt gtttgccata ggtcatttct cctttctttt tggggctgct
    11701 ttaccagttc atcagcccgt agcctttgat acattgatag ttaaggtcat agctctttat
    11761 cttgcaggcg tcgccggaat tgccctcaac ggtatagacg cggctgccgt ccctgccaag
    11821 cacaagcccc acatggtcgg caacgccgtc taaatcccaa tcgaaaaaga ttgcgtcgcc
    11881 cggtgcgata ttctcatagc cgcgtgcgcc ccattgtccc cttgactgaa accaagggac
    11941 accctgccat tcgcagcccg caaagcgggg ttcgcttttt ccggcttgat tgtagcacca
    12001 tgatacaaaa caggcgcacc attccacgcg gctgttaaag ccgtaccaag accagtaagg
    12061 gtagccgccc acatttccga cttgctgttt tgcaagctcc ataagctctt gatttccggg
    12121 gcgcgtaccg tttacaaact ccacgccgct taaatcctcg gacgggcttc cgtcgggaga
    12181 accgccgcca aaaatcagcg gtttgttgcc gcttgtttcc aagtacacat ggaacatttc
    12241 aagctgctgt ggcgttaaaa gctccgacac aaaagaggaa atcggcttgt tttccagttt
    12301 gacattcaag atgtaatact cataagggac ttcctcggtg gtggtttccc cggtttccgg
    12361 gtcggtgctt gtttcagtgc ggtagcgtat ttccacttcc tcggtcagcg tcaaggtgta
    12421 ctgtttttca aagatacgtt caagctctgc ctgtgcgctc tgcggggtgt agctctgcaa
    12481 aagggcggtc aagtaagacg caagttcatg tgggttatgc ccgatactgt caaggtcata
    12541 gcggtattca tcatagccgg ggtgggtgct ttcgatagcg tcaatctcac tttgcagccc
    12601 gttttccaat gcggcataat tgttttcaac tgccacaagg tcgctgtcct cggacgtgta
    12661 ggaagtgcca agcaccccgt tagtcaagcc cgaaaacata gccccgcaag aggacagccc
    12721 tacggaaatc ataataaaga gaagcagcgc ggcaactgca atcaaaacac ccgccgggtg
    12781 tcttgccgca aatgcggcgg ctttcctcgt ttcttctgcg gttttcttcg ctgtctttct
    12841 tgtggcttcc gctgcggctt ttgcccctcc tttctttgcc gcctttgcat actggcattt
    12901 tatctgctgt ttctgcatga aacgggaaag agggttagaa gtaagctgcg ggttgtcgtg
    12961 cagggtcttg tgatactgga agttgacgtt tgccttaaat gctgcctttt ctgcctttgc
    13021 tgcttcccgg taaggtttca gcttatggct gcggtagccc tgttttaact tccgcgcccc
    13081 gtatttcgcg ccgcgctcgg caagttcctc cgatttatgc gccccctcca cgccggaatt
    13141 gtccttttca acagaatgta tcttgttgtg gacgaaaatt cctgcttcct gtgcggggcg
    13201 ggacagcggg tttccctttt tgccgccggg tatcggtttt tcctgttctt caaagtgaag
    13261 tcgggttttt gcctttcctg tggcttcctc aaaggtacgc tccttaacca gtttcttttg
    13321 cttcgggata gctgcctttg ccgcgtccag tttatcggct gctttttctg attttttgat
    13381 gtagggttcc agttccggcg ttgcccgttc ctcgtcggta aactgcaagc gggaagtgga
    13441 agtacgcaaa gcagtagctt cctgctcttt tttgactgcc tttttgtttg cctttcgggt
    13501 atgtgctgcg tcaagatgtt ctatgacgcg ttccgctgcg gcactgtccg gctgtgaaaa
    13561 gtcgccgtct gcttcccggc tgctgatacg ctcggcggtc tgctgtgttt cgttgacttc
    13621 caccacgccg tcgcgggtca ttttctgtgt gattttatcg cgtggtttta attgcttgat
    13681 agtcctgcac ctccaatccg cgccctcgca agggcgcaat actctgcatt taattcaatc
    13741 ccgatataat ggcggtcaag gctttttgct gcaaatcctg tggttccgct tccgaaaaac
    13801 gggtctatga caatcccacc tttgggacag cctgccaaga tacaggtttc cgctaatttc
    13861 gggggaaaag ctgcaaagtg cgccccttta tatgggacgg tgttaatcag ccacacgtcc
    13921 cgcttgttcc gcgtagtcgg catgagcgcg tcgtcatagt agccgccgtc ccgcggtcgg
    13981 tttagtccct gtacctttcc ctgtccggag atttcctgtg tgtatttact gttagtgctg
    14041 cgcgctctgc gataccgttc tgcggtggtg ggggctatgg gttctgcaat agcggcagcg
    14101 tcatagtaat atttcttttc ctttgaaagc aggaagatat gttcatagca gcgggtcggg
    14161 cggtctttgc agctttccgg cataggattt tgtttctgcc atataatatc gctccgcaga
    14221 taccacccct gttcccgcaa ggaaaacgct aaaagccagg gaataccgat taagtccttt
    14281 tgcttgcagc cggtaacgcg gctgttcctt gcaacccgct gtccggtgcg cccttttggg
    14341 tttttcgggt cagcatagcc gcctttattt cctgtgctgc aataggtgtc tgcgatattc
    14401 agccataacg taccgtcctt tctaagcacc cggtaaagct cgccaaaaac agcggtcagc
    14461 ctgtcaatat actgtttcgg cgtgtcctcc tgtccgattt gtgcgtcaag cccatagtcc
    14521 cgtagcgcat agtacggtgg gcttgtaacg cagcaatgga cgctttcaga gggcagttct
    14581 tttaaggcgg caagtgcgtc cctgttgata atcacatctg ttttcatagg ctgctcactt
    14641 cctccggctt cgtcgtcatt acccggtaaa gctcggtatc tttcgggaag cggtctacaa
    14701 aaggcagcac cacatttcca taaaagataa gcccctcgcc cgcttcggtg tggataacat
    14761 acttcatctg ctgcggggaa atattaagct gctttgcaag gatagtacgg tcgccctgcg
    14821 cttgattgag cataaggaca aaatcgctgt tctcaaagat attttccacc tcgcggcttg
    14881 ccaaaaggtc tttgacgttc tgcgtaatgg ctgtgggtat gccgccccat ttacggaaac
    14941 gcttccaaat ctccacgctg taagctgccg tctgttcctc ttttaagagc aagtgaaact
    15001 cgtccatata gtagcgggtg gatttctttt ctgcccggtt tatcgttacc ctgttccatg
    15061 tctggtcttg cacaatgagc atacctaact ttttaagctg cttcccaagc tgctttatat
    15121 caaagcagac aaggcggtta ttcagttcca cgttggttct gtggttgaat acgttaaggc
    15181 tgccggaaac atacagctcc aatgccgccg cgatacgggc agcttccggc tccggctgcc
    15241 ttaacagctc gtcgtaaagg tcgcccaaga taggcatttt tgccgggtcg gggtctgcaa
    15301 ggaacgggcg gtacacattt cttacagccc tgtcaatgac ggtcttatcg acaggctgca
    15361 agccctcctt gccgccaata acaagctcgc agagggaaag gataaaatcg gactttaagg
    15421 ctaacgggtt gtcgtcctcg ctgtaattaa ggtttatatc catagggttc acatactggg
    15481 gcttgccgtc aatgcccctg cccgtagggg aaagacgtat cacttgccca ttaagacgct
    15541 gcacaaggga aaaatactcg gcttccgggt cgcagatgat aatgtcgtcg tcggtaatga
    15601 gaaaagcgtt tgtcatttcc ctttttgccg caaaggattt tccgcttccc ggcgttccca
    15661 agataagccc gtttgggttt ttgagctgct ttctgtcgca gagtatcatg ttgttagaaa
    15721 gggcgttcaa gccatagtaa agggcttgcc ccgtctgaaa aagctcctgc gtgataaagg
    15781 gaatgaaaat agcggtgctg ctcgttgtca aacctctctg aatagggata aggttttccc
    15841 caatcggcac actggataaa agccccgctt cctgctgata gtcaaggcgt gtcaggcggc
    15901 agttgtattt ctgtgcgata cccgccgccg cgaaaatgtc attttccagt ttccgcttcg
    15961 tgtctgccat gtttaccaca aggaacgtaa ggagaaacat tcgctcgttg cggctctgta
    16021 agtcctgcaa caggttcttt gcttcgctgc caaaggtggc aaggtcggac gggattatat
    16081 ccatgtcata gccgcttcta accgcttttt tctgttcctc aatcttcatc ttgtcaaggt
    16141 ctgtgatttt gcgcttaatg gtcttgattg cttccgactg gtcgatactg cggatatgta
    16201 agttgacgat tacgcctgtt tccaagtcca gtatgtcggc aagcatacgg tcgttgagtt
    16261 ccggcgcaag gatttcaagg aagctcgccg cgccgatttt cttccccatg cggaaatatc
    16321 tgccctcgcc aaaatggaaa gaggacgggg cgataaagtc ctttgtagta agccccgacg
    16381 gggtaagcca gtcaaaggaa aaggagaacg gctcgccctc cgggtggaat accccatgca
    16441 gcacctttaa gcgttcatag ccggataagg ggcgggcggt tacgccaagc accttgaaat
    16501 tgttaagtac gtcggtttcg atacgggaaa gccttgactt tgcagccgcc ttgttatcag
    16561 cttcaacggt aaaggtaatg tatttgtgct tcacaagccc gttgttgcct ttactaagct
    16621 gatttttcag catatcggaa tactcggtgc ggatagagtt gaaagcgtcc tcctgtgccg
    16681 ggatagagat agctttttct gcctgttccc gctgcgtccc ttgattgatg aaagaaagct
    16741 gcacgctcac gctcgcgtca aagtaattga ggaaatcgca ccagttttca aaaatggcgg
    16801 tcttatcgtc agcctgtgca agctgataat tgatgtcctc gaacatgacg cactttgaat
    16861 atctcttttc cgtaaccttg cagataccgt ccgggtacat ggcaaggtag ggaatggtct
    16921 gctgtgcggt gcgggctttg ccgtcgcctt ttgcttttcg gatagcttcg gcaatctgtt
    16981 tcttttcggc gcgggtcagc ttacgcctgt ttcctgcggc ttcccgcgtc ttttttgttt
    17041 gtccttttga caatcgctga tacctccttt tcaagttttc gctgcttttc caagacagcg
    17101 tataggtttt cggttctgta aggtcgctcc tttgggcggg taaactttgt ctgaatgatg
    17161 tttcttacca ccacttcaag gggctgtcca tgcttttcat acatggcaag caggaagcag
    17221 gggagcatga cgacaatcat cgccatagcc gcaaggtttg tccctgcgct gcctttgagc
    17281 aaaaaaaaca gcggcagtcc gattaagaga gccgccgcaa aacaaacgat ttgccgcttt
    17341 gtcagattga aagcgacttt tgttttgact ttggaaaggt ctttgggtac aggtacatac
    17401 gccaagaaaa aacctccttt ctgcccttag tgggcgttga atatggattt tgccagtgtg
    17461 ccggatttga acagggaaaa acagaggata accgtatagg cggcaaggga aaataccgcg
    17521 ctgtgcagat tgtctgcgat tatcatatcg tttaccagta cagcgtaaat accgacacat
    17581 atcataatga ggaagccttg aaaaccaaga gcgaacagcc cttttaggta gttgttccca
    17641 atctgtcccc attctctgtt
//
LOCUS       DAEPUT010000086        17600 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.088, whole genome shotgun sequence.
ACCESSION   DAEPUT010000086 DAEPUT010000000
VERSION     DAEPUT010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17600
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.088"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            299..757
                     /locus_tag="KRL22_003088"
     CDS             299..757
                     /locus_tag="KRL22_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1273536.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            818..1093
                     /locus_tag="KRL22_003089"
     CDS             818..1093
                     /locus_tag="KRL22_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1273537.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1152..2426
                     /locus_tag="KRL22_003090"
     CDS             1152..2426
                     /locus_tag="KRL22_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH1273538.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPK
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2556..3608
                     /locus_tag="KRL22_003091"
     CDS             2556..3608
                     /locus_tag="KRL22_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1273539.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMDFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3608..4639
                     /locus_tag="KRL22_003092"
     CDS             3608..4639
                     /locus_tag="KRL22_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBH1273540.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMASGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4731..5543
                     /locus_tag="KRL22_003093"
     CDS             4731..5543
                     /locus_tag="KRL22_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH1273541.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5546..6466
                     /locus_tag="KRL22_003094"
     CDS             5546..6466
                     /locus_tag="KRL22_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH1273542.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NVSTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            6641..7087
                     /gene="rpiB"
                     /locus_tag="KRL22_003095"
     CDS             6641..7087
                     /gene="rpiB"
                     /locus_tag="KRL22_003095"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH1273543.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERYARRLQMIDDIEKENL"
     gene            7117..7782
                     /locus_tag="KRL22_003096"
     CDS             7117..7782
                     /locus_tag="KRL22_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH1273544.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            7892..9394
                     /locus_tag="KRL22_003097"
     CDS             7892..9394
                     /locus_tag="KRL22_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBH1273545.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9706..11295)
                     /locus_tag="KRL22_003098"
     CDS             complement(9706..11295)
                     /locus_tag="KRL22_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1273546.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLVSILFEAVYDLNNNFSNI
                     NYYYREFALPYFYFFGTPVHLSKVELEFVCIGIILSSFLLTILCFTLYKKNKQTKVKF
                     LENVISLFSKVKIELTLILTLILLTLRFHAFTSNKIFYNTNLIIYNFIIISIVYIIYE
                     NIKYNNYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFFM
                     YIYYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEVI
                     GDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDML
                     KNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQS
                     IVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYIDM
                     FIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELENA
                     HMEIIIDADLFKVMLTFRRVN"
     gene            complement(11264..11980)
                     /locus_tag="KRL22_003099"
     CDS             complement(11264..11980)
                     /locus_tag="KRL22_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1273547.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(12520..13320)
                     /locus_tag="KRL22_003100"
     CDS             complement(12520..13320)
                     /locus_tag="KRL22_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH1273548.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNRLGVIRENIILLPETNTNGNTGFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPSILHTPNL"
     gene            complement(13634..14365)
                     /locus_tag="KRL22_003101"
     CDS             complement(13634..14365)
                     /locus_tag="KRL22_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273549.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(14352..15047)
                     /locus_tag="KRL22_003102"
     CDS             complement(14352..15047)
                     /locus_tag="KRL22_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1273550.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAKPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(15049..15840)
                     /locus_tag="KRL22_003103"
     CDS             complement(15049..15840)
                     /locus_tag="KRL22_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273551.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQVFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            complement(15850..16662)
                     /gene="modA"
                     /locus_tag="KRL22_003104"
     CDS             complement(15850..16662)
                     /gene="modA"
                     /locus_tag="KRL22_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1273552.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            complement(17297..17497)
                     /locus_tag="KRL22_003105"
     CDS             complement(17297..17497)
                     /locus_tag="KRL22_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1273553.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
BASE COUNT         6698 a         2152 c         2779 g         5971 t
ORIGIN      
        1 atagttgtta aacataaaaa accatttgta aaaaacaaaa aaatcatttc tctaacaaaa
       61 aaaaccacaa aaaatataaa aaagtatggc tagttaagtg attaacaagt aaaaattaaa
      121 ataaaaatca aaaaaaattt atcaatgaaa gtcagctaaa atcctggaag agagcattat
      181 ttttgggaaa acattttctt ttgtttcaca aaaaaagcca ctttttggca cacaacatgc
      241 tttatataaa gtcaagaaaa actaaggtat aagacaaagg caattaggag gtgtaaatat
      301 ggagtttata aattttgtaa gtgataaagt tatagacctt aaaatggatt gtaaaacgaa
      361 agaagatttc tttaaagaaa tacataataa agtttttgat ttaggctttg taaaagaaga
      421 atttggagaa aaaatattag caagagaaaa tgtatttcca acaggtttaa atttaggaga
      481 ttatggagta gcaataccac atacagatgc agaatatatt aaagagcaat ttatatcagt
      541 ctgtactttt aatgaaccag tagtatttag ttctatggaa gaccaagatg aaaaagtacc
      601 tgtaaatttg gctttcgtat taggacttaa tcaaccacac agtcaattat ctgtattaac
      661 agaattaatg ggaattatgc aaaataaaga gttagttgat aagttgatga gttctactga
      721 taaagaagaa gttttaaaga cactaaagtc tttataaaaa taaaaaagta ctaaaaataa
      781 aaaatataaa aataaaaatt attaggagga aataaaaatg aaaaaaatat tagtagcatg
      841 tggagcagga atagcaacat caacagtagt ttgtgacaag gtagagagat tagttaagga
      901 aaataatata caagcagaag ttatacaatg caaaatagct gaatgtgcaa caaagcaaga
      961 aggagcagat ttaatagtat caacaactat actaccaaca acttataata taccagcaat
     1021 aaaagcaaca gcatatataa ctggagtaaa tacagcagca ttagataaaa aaatattaga
     1081 tgctttaaaa taatcctatc atagatacat tgaaataata ttttataaaa cagaaaaagg
     1141 aggatttata aatggataaa ttattagcag tagtacaata cattttaaat atgggaccga
     1201 cagtaatact accaataaca attgtagtac taggaatgat atttagaatt aagtttacaa
     1261 aagctttaaa gtcaggtctt acaattggta taggatttgt gggtataaac ttagttgtaa
     1321 acctattaac atcaacacta gggccagcgg ctcaaggaat ggttgaaaga ttcggactta
     1381 atttaacagt aatagatgtt ggttggccaa caacagcatc agcaacatgg gcttcaccag
     1441 ttgcaccaat attaatacca gtttgtttat tagtaaactt actattatta tacttcaata
     1501 aaacaaagat attaaacgtt gatatatgga attattggca ctttatagta gcaggtgcag
     1561 ttggatatat agtaacagga agttatgttt gggctatatt ctgtgcaata ctaatggagt
     1621 tattagtact gtttattgca gaaaagacag caaaaaatgt tcaggagttt tatgatttag
     1681 aaggtatagc attaccaact ggttcaacag cttcatttgc tccacttgga tatttagtag
     1741 gtaaatttgt tgaaaaaata ccaggaataa ataaaataca agcagaccca gactctatac
     1801 aaaaaagatt tggtatattt ggagaaccaa tgatgatggg gattatacta ggtataatac
     1861 ttggagcact tgcgggatat gatgtagcag gaatattcaa tgtaggtata tcaatgggtg
     1921 cagtaatgtt acttatgcct agaatggtta gaatattaat ggaaggttta attccaattt
     1981 cagaatcaat aagagatttc ttacaagcaa aatatggaga cagagaactt tatataggtc
     2041 tggatgcagc agtagcaact ggacatccag cagttatatc aacagctctt atacttgttc
     2101 ctataacttt gttcttagca gttatactac caggaaacaa agttttacca tttggagact
     2161 tagcgacaat accattttat atggcattta tagtgtgctt tagaaaaggt aatatagttc
     2221 aatcagttat aacaggaaca atagtaatag ctatatcact ttatatggct acaaactttg
     2281 cagatgttca tacacaatta ttacaacaag caaatatgat gccaaaagga acaacaatgg
     2341 ttacaagtat agatacaggt ggaaacttgc taaaatgggg aatattgaaa ttatctcaat
     2401 tagtttcttc atttggaata ttctaatatg tagttaatag agattactct tttttagtaa
     2461 agtatgcgaa aatttaaaat ttagcagcta ctaaaaaaga gtaatatttt ttataaattt
     2521 ttaaaaatac aaaatacaag aggaggagat ttatcgtgaa agcagcagta ttacatggca
     2581 caaatgatat gagatttgaa gatatagaaa taaaaccatg tgaaagtgat gaagtaaaaa
     2641 taaaagttat ggcagcagga atatgtgggt cagatcctcc aagagtatta aaacattgga
     2701 aatatccagt tccagctata ccaggacatg agttttctgg agtaattgct gaagttggta
     2761 aggatgtaaa aaatgtaaaa gttggagata gagtagttgc aattcctttt ataccttgta
     2821 atgaatgtga atattgtaaa agaggattat tttcattgtg tgatgaccat ggaatgttag
     2881 gagctaaaag ttttggagct tttgcagagt atgtaaatat aaaagctaca aatgtacttc
     2941 caataggaga tatggacttt gaagatgctg caatgataga gccactagca gttgctatgc
     3001 atggagtact taatataggt gttcaagttg gagacactgt agccgtaatg ggtagtggaa
     3061 caatggggca gttggtaata caaggactta aaatagcagg ggcaggaaca attatagcag
     3121 ttgatatatc tgataataaa ttaagagaat caaaggaatt aggggctgat ataataatta
     3181 atgctaaaga tattaaccca gtagaaaaaa taaaagaact tactggtgga aaaggtgttg
     3241 acatagctct tgaatgtgca ggttcaaaaa taactcaaga acaatgttta cttataacta
     3301 aaaagaaaag taagatagga tttttaggga tagcatattc agatataact ttatcagaag
     3361 aagcatttga aaatatattt agaaaagaac tagaattaaa aggtttttgg aactcttatt
     3421 ctgcaccatt tccaggacaa gaatggacta agggaatcaa tctagttaat gaaggaaaga
     3481 taaaattaaa agaaatggta tctcatagat tctcacttga agatacttac aaagcatttg
     3541 aaatgataag agatagaaaa gaagaattta acaaaatatt aattttacca caaggggttg
     3601 aaaaataatg aaagcagtag ttaaaactaa accaggctat gataatgtag aagttttaga
     3661 agtagaagaa ccgaaagcta caggagacaa ggttaaaata aaagtagaat atagtggtat
     3721 atgtggttca gatatacatt catttaaagg tgaatatgca aatataaaag ccccagtaac
     3781 attaggtcat gaattttctg gaattgttgt agaagtagga gaagatgtta aaaatataaa
     3841 agtaggagat agagttacat cagagactac ttttgcaact tgtgagaaat gtatatattg
     3901 tgaaactaaa gattataact tatgcccaac tagaaaaggt attggtactc aagtaaatgg
     3961 aagttttgct gagtatgtat tatcaagaga agaaagcata catgtacttc ctgaaaatgt
     4021 atctttatta tcagcagccc ttacagagcc actagcttgt tgtgttcatg cagctcttga
     4081 aaagactact atagaaagtt ctgatacagt tttaataata ggaccaggac caattggttt
     4141 attattagct caagttgtta aatctcaagg tgctacagtt ataatgtctg gtgttacaaa
     4201 agataaggaa agattagaaa tagctaaaaa tcttggagta gatagaactg taaatgtaat
     4261 ggaagaaagt ttggcagatg tagtgaatga aatgactgat ggaaatggag taaacaaagg
     4321 atttgattgt tctgggttta tgccagcagt taacgaagcc ttaagactgc ttagaaaaaa
     4381 aggtactttc gtacaagttg gaatctttgc taaaaaatta aatgaaatgg accaagaagc
     4441 aataatccaa agagagttac aatatatagg aagtagatct caaaagccaa gttcttggat
     4501 tacagcatta gatttaatgg caagtgggaa agtaaataca gaagctttag ttactagaac
     4561 tgttggttta gacgaattta aagaaggtat aacagcttta atgaacgggg aagaaataaa
     4621 agtagcagta aaatcttaaa aaaacatttg tattatttta aaaaaaattg taaaatctac
     4681 tgtaggataa aaaaatgtaa ggtcttaaaa aataacagga ggaagaaagt atgagcactc
     4741 ttagagatca ttctaataat attagaaaaa acataataaa aatggttgca gaagctaaaa
     4801 gcggacatcc aggtggttca ttatcaatag ctgatatgtt gacagtatta tattttgata
     4861 agatgaacgt atgtgcagaa aatccaaaaa tggctgatag agatagattt gttctatcaa
     4921 aaggtcatgc agcaccagct ttatatgcta cactagcaga aaaaggattt ttcccagaag
     4981 aagaattaat aacactaaga aaatttggtt ctaagttaca aggtcaccca gacatgaaaa
     5041 aagtagcagg aatcgatatg tctactggtt ctcttggtca agggctatct gcagcaaatg
     5101 gtatggcact tgcaggaaaa ttagataaca aagactatac agtatatact atattaggtg
     5161 atggagaaat ccaagaaggt caaatatggg aagctgcaat gacagcatca cattacaaat
     5221 tagataattt aattgcattt gttgacttaa atggattaca aatagatggt tctaatgaag
     5281 aagtaatgaa tgtaaatcca gtagatgaca aattcaaatc ttttggatgg aatgtaatag
     5341 taataaatgg acattctttt gaagaaatag gaaatgcagt tgatgaagct aaaaaagtta
     5401 caggaaaacc aactgtaata atagctaaaa cagtaaaagg taaaggtgtt tcatttatgg
     5461 aaaataatgc tgcatggcat ggaacagctc caaatgcaga acaagcagag caagcattga
     5521 aagatttaga aggaggtcta taggaatggg aatagcaact agagaagctt acggacaagt
     5581 gttaaaagaa cttgcagaaa ataaagatat agtagtatta gatgcagatt taggaaaagc
     5641 tacaaaaagt atatcattta aagaagttgc cccagataga ttttttgaca tggggatagc
     5701 agaaggtgac atgattggta cagcagcagg tctagctact tgtggaaaaa taccttttgc
     5761 gagtactttt gcaatatttg cagcaggaag aggctatgag caaataagaa actctgtagc
     5821 atatccaaat ttaaatgtaa aaatagcagc tactcatgca ggtgtaacag taggtgaaga
     5881 tggtggtagc catcaagcta tagaggatat atctctaatg agaggtatac caaatatggt
     5941 tgtattaaat ccagcagatg ctttagaagc aagacaagct attcttgcat ctattgatta
     6001 taatggacct gtttatataa gattaggtag agctgcaact cctgatgtaa acagtgaaaa
     6061 ttataaattt gaaataggaa aaggaactgt tttaagagaa ggttctgaca taacagtaat
     6121 agctacagga ataatggtag caaaagcctt agaagcagca gaagaacttg ctaaagaagg
     6181 tataaatgta gaagttgtta atgtatctac aataaaacca ttagatgaag cattaataaa
     6241 agaaactgct aagaaaactg gaaaagtagt tacagcagag gagcacagta taataggtgg
     6301 tttaggttca gctgtatgtg aagctttagc agaaactaaa gatgtagtag ttagaagaat
     6361 tggtgttaaa gatgtatttg gtcaatcagg tacaccagct gatttattaa aacactatgg
     6421 tttaactaca gaagatatag taaaaaatat aaaagagttg ttatagatat aaatatatct
     6481 aaataacaaa ttgatttgac ataagtcaat taaagctgtc ttaaaaatag aaagaaattt
     6541 ctacaatggg acagctttat ttttacaata ctttattttt atgataatta taaaatagtc
     6601 tgaaagtaat caaaaaaatt ataaaaagag gtgctattta atgaaaatat ctattggatg
     6661 tgaccatggt ggttatgaat taaaggaata tataaaggaa aatttaataa ataaaggtat
     6721 agaagttgaa gatgtgggta caaattcaaa agaaagtgta gattttccaa tatatgcaaa
     6781 aaaggtaagt caaaatgttc aaagtaaaaa atctgattta ggcatacttt gttgtggaac
     6841 aggaataggt atgtctattg cagcaaataa gtttaaagga atcagagcag ctgttgtttc
     6901 tgactgtttt tcagctaagg caactagaga acacaataat acaaatgtac tttgtttagg
     6961 agaaagagtt attgggaaag gattagcaat gagaattgtt gaagaatggt taaattcaag
     7021 ttataatgga gaaagatatg caagaagatt acaaatgatt gatgatatag aaaaagaaaa
     7081 tttataaata tataatttat aacaaggggg agcgttatgt ctattatttg tgcttcaata
     7141 atgtgtgcag accaaatgaa gttaaaagag gaattagaag ctcttgaaga agcaggtgta
     7201 aaattacttc attgtgatgt tatggatgga atatttgtta aaaacttggc tatgggacca
     7261 gagttattaa aatcaataag tgaaaataca acaatacctt tagacataca cttagccaca
     7321 gaaactccag ataaatatat tgatatgatg tcttatataa agccaaaata tatttctttt
     7381 catgtagaat caagtacaaa tgtaaaagct gatatacaaa agttaagaaa ttatggtata
     7441 gggccagtgt tagcaataag ccctcaaaca agtgtggata aaatagaaga atatataagt
     7501 ttagttgagg gtatcttagt aatgacagta aatccagggt ttgcaggtca aaagtttaat
     7561 ctttctgtat tggataagtt ggataaactt acagagatac taaaagatta tgataatcct
     7621 ccatttatag aggttgatgg aaatataaat aaggatacta ttaaacttat gaatggtaaa
     7681 aaagtagata tatatgttgt tggtacttca gctttattta atgataagcc tccaatttca
     7741 tataaagata aaatagaaga actaaaagaa agtataaagt aaccatgtaa taaaattata
     7801 atatgtttct gtttaatagt aaaaatttag gtggaaacaa gaaattttat aatatttaat
     7861 aaaaattttg gttgagtaag gagaattttt tatgggagac ctatataaac tacaaaatgg
     7921 tactgatatt agaggaatag cgtatgaaaa tgattctaaa gaagttaacc taactgtaga
     7981 agaagtaaaa aaaatagcta aagcgtttca tatttggtta aaagaaaaga ctaagaaaga
     8041 taaagtaact gttgccatag gaactgattc taggataaca ggaagccaat ttagaagtac
     8101 tgttattgaa actttaacta atgatgattg taatgtaatt gattgtgaga ttgccacaac
     8161 tccagctatg tttatgacaa ctattatgga tggatacaat tctgatgggg cgattatgat
     8221 tacagcaagt cacttacctt attactataa tggtttaaag tttttcacag aaagtggagg
     8281 tttagaaaaa actgatataa aagagatgtt ggatatagct gttaaaaatg atagtgtaga
     8341 ctatgaggaa gtaaataaaa aaggtgaagt tatagtaaaa aatttaatag aagattattc
     8401 taatttatta atagataaaa ttagaaaagg tgtaaattca agtaaaaatt atgaaaagcc
     8461 tttttctggg cttaagatat tggttgatgc aggaaatggg gctggtggat tctttgctga
     8521 aaaagtttta cacatactgg gagcagatac gacaggtagt cagtttttga acccagatgg
     8581 tatgttccca aatcatatac ctaatcccga aaacaaagaa gcaatggaaa gcatatgtaa
     8641 agctgtgtta gataataaga gcgacctagg aataatcttt gatacagatg tagacagagc
     8701 tgctattgta ggtaaaaatg gcaaaccaat aaataaaaat gctcttatag ctgttatatc
     8761 atcaatagta ttagaagaac atccaaaaac agctatagta acagattcga ttacttctga
     8821 aggacttgct aaatttataa atgaattaca aggaagacat catagattta aaagaggata
     8881 taaaaatgta ataaatgaag ctataagatt aaatagtgaa ggtgaagagt gccatttagc
     8941 tatagaaacg tctggacatg ctgctttaaa agaaaattat ttcttagatg atggggcata
     9001 tttaatagct aaaattttaa taaaagtagc aaagctatcc ttagaaggaa agactataga
     9061 agaattgata gaaaaccttg aagaagctca agaagagaaa gaagttagaa taggcattaa
     9121 taaagaagat tttagaccat atgcagagga tatattaaaa gatttagatt ctcatgtcaa
     9181 gagtattgat ggatggtctg tagcaccaaa taattttgaa ggcataagag ttaattgtga
     9241 tgaatcaaat ggagatggat ggtttttact tagaatatca ctacatgaac cattattagc
     9301 tttaaatatt gaatcaaata aaattggcgg agcagaacaa atttattcta agttaaaact
     9361 tttcttagaa aaatatgatt taaaaggtct ttagggtaaa tagaaagaat atatttatat
     9421 tgaagaataa atgtaaattt gtacctaaga ttacaaatat tacaaaattg taatcttagg
     9481 taacagagat gtaactgatt atggaaacac tatgtgatat tatagataca gagagatgaa
     9541 atatgtgatg aattatagag aaatataatt taaaatgtat taatatcaca ccaaaaaggt
     9601 ataatcaaaa aatatgtaaa tataaacccc aacatttaga aaaagacctc taaggaggtt
     9661 tttttcttgt ttaaataact taaaatatat ttttatatca atatatcaat taactcttct
     9721 aaaagtaagc attaccttaa ataaatcagc atctataatt atttccatgt gtgcattttc
     9781 taattcaatt atattttgag caattgataa accaagacca gagccatctg tttttctaga
     9841 tatatcaccc cttctaaatc tttctattaa ctcttctggc tttagattta gtttatcatt
     9901 tgaaatattt ttaaacgtta atattatatt ttcttccttt ataaacatat ctatatagac
     9961 cctagtgtta ggcatagagt attttaatat attgcaaatt agattctcaa aaactctcca
    10021 agttttttta ccatctatca tggtaaaaac agcatattca ggtgtttcta ttataaaatc
    10081 taaactgcta ttttgaattt tgtcttcaaa ttctacaata ctttgaatta aaagttctct
    10141 tatatcggtt tttgttatat taaattctac atctccacta cttagcttag atgcttcaaa
    10201 tatgtcatct attaataatt ttaatctttg tgatttttta tctaaaatat ttatatagtc
    10261 atttatagtc tctctgtcaa agtcattatt ttttaacata tcaacatagc ttaatataga
    10321 tgtaagtgga gtttttaagt catgagatac gtttgtgata agctctgcct tcatcctttc
    10381 attttttata ttagcatcta cagcagtttc aagaccgcct gttatattat ttatactttt
    10441 ggctaaagta gatatttcat catctcctat aacttctaat ttatacttta aattgccatt
    10501 ttctatattt tttatatttt ttgatatgtt atttatgtaa ttaaacttaa cagataaaaa
    10561 gttgtatata taaaaatgaa aaactgtgtt tacaagtgta aataaaatta ctatagctat
    10621 tgcctcagca taatatatat acataaagaa tatcaaaaca agatattgga taatagcttg
    10681 tacaactata gatattaaaa atactatagc taatttttta tttatagttt ttttattata
    10741 catactaagt aagtttgaaa agaatacata tgttatagac atatctttta gattatagtt
    10801 attatattta atattttcat atattatata gactatagat ataattataa aattgtagat
    10861 tattaaatta gtgttgtaaa atattttatt acttgtaaat gcatgaaacc ttaaggttaa
    10921 tagtatcaaa gttaatataa gtgtaagttc tatttttacc ttagaaaaaa ggcttatgac
    10981 attctctaag aatttgactt tagtttgttt atttttttta tacaatgtaa aacatagtat
    11041 agtcaataaa aaacttgata atataatacc tatgcagaca aactctaatt ctacttttga
    11101 caaatgtaca ggagtaccga aaaaataaaa ataagggaga gcaaactctc tataataata
    11161 attaatatta gaaaagttat tattcaaatc ataaactgct tcaaataata tagaaactaa
    11221 tagaaacagt aataataata aaataaattt tgctttagaa tcattaataa ttaagttttt
    11281 caattttgta accaatgccc cacaccacct ttaaatattt tggttctttt ggattaattt
    11341 caatcttttc tctaattctt ctaatatgaa cagcaatagt tctctcacaa ctataagcat
    11401 cctcattcca gacattttca taaatctcat gagaagagaa aattttacct tttcgtgaca
    11461 taagaagtgt aagtatttta tattcaagtg gtgtcatttt aatttcttca ccatctaaag
    11521 aaactatttt tgtatctgta tttagctcta ggccaccact ttttagaata taattagtat
    11581 catttgagtt atttgtatta ctaaaatcac ctaaatttat ataccttcta agttgagatt
    11641 ttactcgagc agtaagttct agtggattaa atggtttagt tatatagtca tcagcaccca
    11701 tattaagacc tataattttg tccatatctt ctgattttgc agataagaga attattggta
    11761 tattcctttt ttctcttatt ttaagtgtag ttttaagccc atctaaattg ggcatcataa
    11821 catccattat tattaactta atatcatttt cgattagtat gtccaatgct tcaagtccat
    11881 catatgcctt taaaacatta aagttatcag gtctcaaata gaactctata gcatcaacta
    11941 tctctctatc atcatctaca accaatatat tttgattcaa cttattaacc cccttgaaat
    12001 tttattttta accaattttt attttatacc aaaaagaggt attagaaaac agtaagccca
    12061 ttcattatga aataaaaact agtactttta atatattgtc aatgcatata gtaaatttaa
    12121 aagtatagac gcccatatta atctgaaggt aaaagtttat gaaaatatct agggtaatct
    12181 atcacacttc ttatgttatt ttggtttatt aattttttag gtttaaacat atattaacaa
    12241 atataaataa caaatgagtt tcataattat taagaattta taacaaatat ttattttaat
    12301 gtagtttaat ataaacaggt agtttaatgt aggtatgtat aaagcattta ataaggctta
    12361 taggttttaa tgatgatatc tttatatatt ttaagagatg atgaaattag atatgggtaa
    12421 tagttgtatg agaaaaagta gtatagcaca aaaagtgcta tatcacaaaa tctcaaataa
    12481 tttccttttt ataacttaaa ttaaaagaat aaatatttct tataaattag gtgtatgaag
    12541 tatagaagga acatctttat tatttaataa cttatcaaat gatttatggt cagacttata
    12601 gccaatacct tctctatatt ctaattcatc aacaattttg tattgttgac aggcattttt
    12661 aaccttttca tagtcttcag tagaatgagc tttataaact atcttattat taaaagttat
    12721 tttatcagca aatttaggtt ttacaaaata tttagcatct tttattttac cagcattata
    12781 taaattttgg ataacagaac cattttttaa atgttgtaaa tggtcatcta acttataagt
    12841 atgtgctata tgagttacat ttttaaattt ttcttcaaat gtaagagcaa ttttttccat
    12901 gtaattgaag ccagtattac catttgtatt tgtttctggt aataatatta tattttccct
    12961 tattacgcca agtctattaa gagaagctaa aaattctcta tttctatatt ctgatttttg
    13021 tatatttgtt aggttttcat attttttata tttatcaaag acggatatac cacatccagt
    13081 agatactaaa accacaaata catgattttt tcctctttct tttatagcat taacaatagc
    13141 actcccagcc cacaacactt catcatcttg atgttgaaca tagaagacaa cataatcttt
    13201 aaatttttta tgactataat tcacatagct actaaaagcg gttaaaatca aacataaaac
    13261 tagaataata gatagaattt tatatttatt tatagtaaat tttttattct taaatgtcat
    13321 ttaatcatct cctgaaaagt tgtcttagtt atattatcaa acaaagtact aaaaattatt
    13381 tcttaaatgc tgaaaaatat agagtagatt aatggaataa aattttttta ttagtttaaa
    13441 ataaagaaaa catttatgta taagactaat caaaatatta atgattgata ggaattgaga
    13501 tttaaaggga ttgtacattt attcgggatt cattttaata gaattttact ttagtactta
    13561 gaataaaagt aataactttt taaatttaaa gagtacacat atatatttgt gtactccttg
    13621 atgatatgat tgcttattta ctacaaaaac agagtctttt taaacctaaa atatttgatg
    13681 caccagctat cgtagttcca taatagtaaa ctggtttgtt aagtgataga aaatttataa
    13741 ttgagttatt acataatgta cttcctgtgc aaatcactaa atcagcccaa gatattacat
    13801 cttcataatc tcgtatacca tcttcaatct taacattata ttgaatagta tccacaaatt
    13861 caggatttaa atctaatact cttgtttcga aaaagtcctt aatattatca attatggctg
    13921 gttgatatcc tataattgct acttttggat taccaaattc catttttata aactcaggga
    13981 atttttttgc acatacctct ggctcgttat ttttacaatg aatggttcta tccgtcttgc
    14041 ctaagtattt cataactgca tttaatgatg ctataaaaag acttctatca tgaggattgt
    14101 catgtaaatc taatgataat atgtctttta aagaaccttc aaatgtagat ggagtagaag
    14161 taaatgcttg tcctttagct cctttaaagt cagcttcaag cattatttct ttaccaacta
    14221 taattggaaa atctttacgc ttagtatttc caattgcttc ttttgaagat agagatttgg
    14281 acacaatact tatcatatcc atatttaaat tatatttatc gacttgtact aatagataat
    14341 ctctcaaaat atcaaatata ttcatagaaa aaagattctc ctttattttt tatttcttca
    14401 tttaaatcaa aaatatgatt tatttttcca ttgttcatta ttcctatctt atgagcaaaa
    14461 aacattgctt cagaaatatc atgagtaaca tgaatcactg ttggtttgta ttttatgtag
    14521 acatccttca aaattttgct tatatgtttt tttgtaatat aatccaatga actcataggt
    14581 tcatctaaaa gtaatatatc aggtttagct attaaggcac gtgcaaaagc aactcgttgc
    14641 ttttcgcctc cacttaaatt tttaggatac ctatttttta tatcttctat ctgcattaat
    14701 ttagacaagt ggttagcctt aagaatctgt tcatctatag gtatttttct taatttaagt
    14761 ggaaacctta tattatcttc aacattcata tttggaaata attcaaaatt ttgatataca
    14821 aatcctatat ttctattttc tggaggtaag tttgatatta aattttcttt gtatgataca
    14881 tttcctttag cagatggata tcttcctgct aatgtttcta ggaatagagt tttacctgac
    14941 ccactagctc ctaataaaac aaagtattca tgattattaa tatttaaact attttcttgt
    15001 aatttaaaat taggtaaatc aagagataaa ttttttattt ttaacatatt aattcttatc
    15061 aacctctcta ttaaaaaata tctcaaaaag catcaagcat gtaagtgaga taaatatcaa
    15121 aattacagct attccgattg caatgtctat atcaccagta gacatattta aatatataga
    15181 tgtaggaata atttcagttt tcatacgtgt agaacctgct atcatagcta ctgcaccaaa
    15241 ttcaccaagt gctcttgacc aagtcattac agttgcagat atgattccag tttttagatt
    15301 tggaagaatt ataaatctaa atgcttccca actattacat ccaagggtac gtgcaacaaa
    15361 tatcatcttt tcattacttt catttagtga agtgtgaagt attttaatag taagtggaag
    15421 atttacaaat acttgtgcta aaactatacc ttgctttgta aatataaaat caagcttaaa
    15481 aatcttataa atggaatctc caatccccat tcttccaaac aaaagtaaaa gagcaattcc
    15541 tgatactaag tgtggaagag acatagggag atttattatc tgtataatca gttttttaaa
    15601 tggtaattta gtaatatgta aaaaatatgc tactggaata gctaataaaa ggcatactat
    15661 agtagatatt aaagatgttt taatactaag tgttattgca tactgtactt ccactgattt
    15721 taagcatata ggaacataac ttatcccttt aatgattaac ataagaagtg gtgatacaat
    15781 aaacaaaaag actatagcaa aaaatccagt aagtagtgta gtaaaaaatt tatttttcaa
    15841 gtttaatcac tacttaacag gttcaaaacc atatttttta aatatctgtt tagcttcgtc
    15901 tgactctata taatttataa atttattagc taaatctttt ttatcactat agtttacgat
    15961 tcctgctgat ataagttggt ctatattttt atcttgggca atttctataa cttctacatc
    16021 ttcattgcca aagactgaat cttttgtggc tattgtagca tcagctttac ttgatgttaa
    16081 ctgtacaatc atttcattta cagttgcagc tgtagagaca acattatcat ttatagattt
    16141 taaattattt ttttcaagta ttttttgtgt agttttacct atagcattag actctttgtc
    16201 tcccaaaata agtttaactc catctttatt taagtcttcc aatttttgaa tattagctgg
    16261 atttccttta ggtacaacta ttgcaggtgt atgatgtgca accgttttat gttcacctac
    16321 aagttctttt tcaaaggcct ttgaataaat tggttcagaa ccaacaataa atacgtctcc
    16381 tttgtgactt gtctcaattt gagctattag ctgtgcagaa cctgcatagc tatattcaac
    16441 tttgacatta ttttctttct caaatttttt tgctatttca tccattggtt tctttaaacc
    16501 tgcccctgaa tagacaaaaa gagtctcttt ttcttttgaa tcatcagctg ttgtcacttt
    16561 agtattagat tcatcattag ctttgttttc tttagaatta catgcagtaa tacttaatga
    16621 aataatcata gctaaagcta gtactgaaag ttttttaaac ataagatatt cccccttagt
    16681 aaattagtgt aaattctttt ttagtatatc atactaagaa aacgatgtct aagtttttgt
    16741 tatgttttat aatgttttgt tatgttttgt tatgtatagt taagaaaaaa tctatttata
    16801 atgtcatttc cataggtagt tattttattt ttaattttta ttaatacttt aaagtatttt
    16861 aaatttaaaa acttaaatca aattaactta ttgtagattt tttatttttt aactaatttt
    16921 atatttatta tatttcagtg aaaaaataga acattgaaac atatagatat gttttaattg
    16981 ttttttatta acaaattact aaaagtgtta tatcagaatt gaatacaaaa gaaagagtat
    17041 gtatttatga gatagttgaa aattttggtg tgccacaact aaaattatta tattactata
    17101 tattctaatt aaaagagtac ttgtaggttt aagtacatac tttataaata tatttttgtc
    17161 agatttattt tataaaaagt atttagacta agtattattt ttaagtattt tcttgttgaa
    17221 gttatttttt ccttttttac aaaatgcgta aataaaaaaa agactcttaa aagagtcttt
    17281 ccgaaaaatc tatatattat aatatagtta tattttctgc ttgaggacct ctagcgcctt
    17341 taactatatc aaagcttact ttttgacctt cttctaatga tttaaatcct gaagtttgta
    17401 tagctgagaa atgagcaaat acgtcatctc cactttccat tgatataaat ccaaatcctt
    17461 tttcattatt aaaccatttt actattccat tattcattaa aaatactcct attaacctat
    17521 atcaagatat acttgattta cttgtgtatt accacaaata ctattgtatc atagattaac
    17581 ataaatgtct atttaattat
//
LOCUS       DAEPUT010000087        17007 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.089, whole genome shotgun sequence.
ACCESSION   DAEPUT010000087 DAEPUT010000000
VERSION     DAEPUT010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17007
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.089"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            13..981
                     /locus_tag="KRL22_003106"
     CDS             13..981
                     /locus_tag="KRL22_003106"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBH1273554.1"
                     /translation="MYFGNKIFIVTDENIAKLYLDKVKNNLSESGFEIKSLILKSGEE
                     TKSFNTLPKIYDSLLDFKLTRKDLIITLGGGVIGDLGGFAAATFLRGISFIQIPTSLL
                     AQVDSSVGGKVGVDLERGKNLVGSFYQPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGC
                     IKDKTFFNKLLSLKNREEVMQHIEYIIHKCCFIKKTVVEADEKDFGDRMLLNFGHTLG
                     HAIEKYYNFTGYTHGEAVAIGMYKITLESEKIGITKKGTSELIKSILMNYNLPYEIEL
                     RDNKSIVDAISLDKKNLGDTLKIILLKDIGESIIYNTTSKFFQEVR"
     gene            981..2294
                     /gene="aroA"
                     /locus_tag="KRL22_003107"
     CDS             981..2294
                     /gene="aroA"
                     /locus_tag="KRL22_003107"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBH1273555.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLTFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGKTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            2272..3351
                     /gene="aroC"
                     /locus_tag="KRL22_003108"
     CDS             2272..3351
                     /gene="aroC"
                     /locus_tag="KRL22_003108"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBH1273556.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDKIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            3354..4550
                     /gene="pheA"
                     /locus_tag="KRL22_003109"
     CDS             3354..4550
                     /gene="pheA"
                     /locus_tag="KRL22_003109"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBH1273557.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVHFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKNFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            4597..5406
                     /gene="aroE"
                     /locus_tag="KRL22_003110"
     CDS             4597..5406
                     /gene="aroE"
                     /locus_tag="KRL22_003110"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH1273558.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            5418..5951
                     /locus_tag="KRL22_003111"
     CDS             5418..5951
                     /locus_tag="KRL22_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBH1273559.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            5972..6811
                     /locus_tag="KRL22_003112"
     CDS             5972..6811
                     /locus_tag="KRL22_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBH1273560.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            7079..8560
                     /locus_tag="KRL22_003113"
     CDS             7079..8560
                     /locus_tag="KRL22_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH1273561.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            8593..12030
                     /locus_tag="KRL22_003114"
     CDS             8593..12030
                     /locus_tag="KRL22_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH1273562.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIVDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVELGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENTKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNGLENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            12048..12794
                     /locus_tag="KRL22_003115"
     CDS             12048..12794
                     /locus_tag="KRL22_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBH1273563.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(12743..13051)
                     /locus_tag="KRL22_003116"
     CDS             complement(12743..13051)
                     /locus_tag="KRL22_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH1273564.1"
                     /translation="MNFLKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIEKYKT
                     SYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
     gene            13852..16904
                     /locus_tag="KRL22_003117"
                     /pseudo
     CDS             13852..16904
                     /locus_tag="KRL22_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897035.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
BASE COUNT         6931 a         1841 c         2802 g         5433 t
ORIGIN      
        1 gaaataaaaa aaatatattt tggaaataag atttttattg taactgatga aaatatagca
       61 aaattatact tggataaagt aaaaaataat ttaagtgaat ctggatttga aattaaatct
      121 ttaatattaa aatctggtga agaaacaaaa tcatttaata ctcttcctaa aatatacgat
      181 agtttacttg actttaagtt aactagaaaa gatttgatta ttactttagg aggaggggta
      241 ataggtgatt taggtggatt tgcagcagca acttttttaa gaggtataag ttttattcaa
      301 attccaacat ctttattagc acaagttgat agttctgtag gtggaaaagt tggagttgac
      361 cttgagagag gcaaaaattt agtgggaagc ttttaccaac caaaggctgt gtttatcgat
      421 ccaaatgtat tattatcact tccagaaaaa ttctatagag atggaatggc agaagttata
      481 aaatatggat gtataaaaga caaaactttt ttcaataaac ttttaagttt aaaaaataga
      541 gaagaagtaa tgcaacatat agaatacatt atacataaat gttgctttat taaaaaaact
      601 gtagttgaag ctgatgaaaa agactttgga gatagaatgc ttctaaactt tggccataca
      661 ttaggtcatg ctattgagaa atactacaat tttacgggtt atacccatgg agaagctgtt
      721 gccataggaa tgtataagat aactttagaa agtgaaaaga taggaattac aaaaaaaggt
      781 acatcagaac ttataaaatc aattttaatg aattataatt tgccttatga gattgaatta
      841 agagataata aatctatagt agatgctata tctcttgata aaaaaaatct aggtgataca
      901 ttaaaaataa tacttttaaa agatattgga gagagtatta tatataatac tacttctaaa
      961 ttttttcagg aggtaagata atgggaagtc taaaaatata tccaagtaaa ttatctggag
     1021 atgtaaaaat accaccatca aaaagtatgg cacatagggc agttatttgt tcatctctaa
     1081 gcaatggaaa aagtagaatt tctaatatag atttttctga tgatataata gctactataa
     1141 gagcaatgac atcattagga gctattatag aaaagaaaga agatatttta gaaatttcgg
     1201 gaattttttc taaagaaggt attttaaata gagagaatca gttgaatcaa cctaaattga
     1261 caatagattg taatgaatca ggctctacat tgagattttt agtacctata tctttaacat
     1321 ttgatggtgt aaaaaggttt ataggtagag gtaatcttgg aaaaagacca cttgatacct
     1381 attatgagat atttgacaga cagaatataa aatatagtta caaagaaaat cagttagatt
     1441 tgattatatc gggtaagctt aaaccagatg aatttagagt aaaaggaaat ataagttctc
     1501 agtttatcac aggtttactg tttatattgc ctacgctaga aagtgattca aagataataa
     1561 ttactactga gctagaatct aaaggatatt tagatttaac tctttcaacg ataaaagatt
     1621 ttggggtaga aattataaac aataactata aagaatttat tataaaagga aatcaaacgt
     1681 ataaagcgag agattataaa gtagaaggag attattctca aggagcattt tatttatcag
     1741 cagatgctat aggagaagat attagcatat tagaccttaa agaagattct cttcaagggg
     1801 atagtgaagt agttgaaatt ttatctagga tgggaatgga aatattaaga gaaggcaaca
     1861 aaataaaagg aataacaaat ggtttaaatg gtactttgat agatgcatct caatgcccag
     1921 atataatacc tgtattatct gtagtagcat ccttaagtat agggaagact acaataatta
     1981 atgctggtag gcttagaatt aaagaatgtg atagacttca tgcaataaat gttgagttaa
     2041 gtaaacttgg agcaaatata gaggagaaag aggatagttt gataatcgaa ggagtaagca
     2101 agttaaatgg tggagtagag gtgtggagtc acaaagacca tagaattgct atgacacttg
     2161 caattgcttc ttgtagatgt gataaaccaa taatattaaa agattttgag tgtgtatcaa
     2221 aatcttatcc acattttttt aaagatttta agatgttagg aggtcgaatt gatgagtgga
     2281 atatggggaa ataatttaaa agtatcaatt tttggagaat ctcatggaaa tgctataggt
     2341 ataaatatag atggtcttcc ttcggggatt gaacttgacc ttgataagat tgataaagaa
     2401 atgaagagaa gagcacctgg aaaaaattct atatctactt caagaaatga aagtgatata
     2461 ccagaaattc taagtggata ttttaatgga agaactacag gaacgccatt atgtgcaatc
     2521 ataagaaata gtgatactcg ttcaaaagat tatggagagc ttaaaaattt aatgagacca
     2581 ggacatgcag atttcacagg taatgtgaga tattctggat ttaatgacta tagaggtgga
     2641 ggtcattttt caggtaggat aacagctcca ttagtatttt gtggggctat atgtaaacaa
     2701 attttatcac aaaaaggaat agagatagga gcacacataa aaaaaattaa aaatatagaa
     2761 gatatgagtt ttgattatgt aaatatttca aaacaacagt tatcaaattt gcaaactttg
     2821 gaactacctt tacttgattt atcaaaggaa gaagccatga aaaatacgat tatagatgca
     2881 aaaaatcaag gagattcagt tggtggtata attgagtgtg cagtagtagg tattaatgta
     2941 gggcttggaa atccattttt tgactctgtt gaatctactt tatcacattt gttgttttct
     3001 gttcctgctg taaaaggtgt agagtttggt ttaggttttg aacttgcaga tatgtatggg
     3061 tctcaaagta atgatgaaat gtattatgaa ggaaatcaag ttaagagcaa aacaaataac
     3121 aatggaggaa ttataggagg gattactact ggaatgccaa taattttcaa agtggcaatt
     3181 aagccaactc catcaattag cagacaacaa aacacagtta atataaaaga taaaaaggac
     3241 gatattttat atattaaagg cagacatgac ccttgtatag ttcaaagggc tatacctgta
     3301 atagaagcag taacagccat tggaattttt gatttgatga aaggacgata ataatggagg
     3361 atttaacgag atatagaaat gagattgaca atatagataa agagcttatt caattatttg
     3421 aaaagagaat gaatacagtt cttgaaattg ccagacataa aatgaaaaat aacactacta
     3481 tacttcaaaa agatagagaa gaaaaagtac taagtagagc cgtagataat ttagataata
     3541 aagcatattc acaagaaacg gtacattttt ttaattctat aatggaaatt agtagaggat
     3601 tacaaaaaag attgatagat aatgatggtg agcagaaaat cgagtttagt ttagattcat
     3661 caaataagaa ttttgatttg tcaaatgtaa ataaatataa gtctttaaaa gatgaattaa
     3721 ataaaaaaaa tatcctagta ggatttccag gaaaatcagg ttcatttaca gaagaagcac
     3781 taaataaatt cttcaacaaa aaaatatcaa aaaaacaatt taaagaattt gaagatgttt
     3841 tcatagcact taaaaataaa gaaataaact atggaataat ccccatagaa aattcatcta
     3901 caggagctat ctctgaaact tatgaccttt tgagaaagta cggtttttat atagttggag
     3961 aagaatgtat aaaaatagac caaaatttaa tagggataaa agacacaaag cttgaagata
     4021 taaaagaaat atattctcat ccacaaggta taggacaatg tagtgaattt ttaaaacaaa
     4081 atagtacatg gaaattgata ccatttaata acacagcaac aagtgcagaa cttgtaagaa
     4141 aacttcaaga taaaacaaaa gcagcaattg caagcaaaaa agctgcaagt atttatggat
     4201 tagaaataat aagtccttgt ataaatgata tagcaaacaa ctatacaaga tttgtagtaa
     4261 tcagtaatca aatacacatt gaagaagaat caaacaaaat gagtgtagta ttttctgttg
     4321 aacatgaagc aggaaaactt tataaagtac ttggatactt tgctaaaaat aatataaata
     4381 tgacaaaaat agaatcaaga cctatgaaaa atgcctcatg gagatatttc ttttatatag
     4441 attttgagtg ttctatatac aatgctaaag tgtacgattt attagaattg atagaacata
     4501 atacagcata ttttaaattt atgggagtat ataaaaataa aactgaatag ataagataaa
     4561 tttttattta atttataatt attaggaggt gtaagtatga attttttcgg tctagtaggt
     4621 gaaaaactct ctcacagtgt ttcacctcaa atccacaaga gagtattcga gatattgaat
     4681 attgaaagtg cttataaaaa ctttgaaatt tcaaaagaag atatatctaa gctagacggt
     4741 gctataaaat tattaggaat acaaggggta aatgttactg taccatataa ggagcgtatt
     4801 atgaaatatc ttgattttat atcaccagag gcaaaacgta taggagcagt taatacaatt
     4861 ttacttagag aaaatatgtt atatggttac aatacagatt actttggtct tgatagtatg
     4921 tttaaaatgg ctaatattga tgttcaagga aaagtagcag ttatattagg aactggaggt
     4981 gcttctaaag ctgctcttac atattttatt gattctggta tagaaaagct ttatgtttca
     5041 actagaaaaa aggatgataa aaaattatta aatagtaaag ctatattaat agattatgaa
     5101 gaacttaaac atataaaagg agatataata ttaaatgcta caccagtagg tatgtaccct
     5161 aatgtaggaa tttcaccagt gtcaaaatct attatacaaa attttgatat attaatagat
     5221 ttaatttaca atcctggaga aacagagttt ttaagaattg gtaatagtat gggtaaaaaa
     5281 acttgtgatg gattatatat gctggtgggg caagcaataa aatctcagga aatttggcaa
     5341 gatactaaaa tagataatag tattttagat gttatatata atgaactaaa attagaattt
     5401 ttgtaaggga gattgttatg ataaataaaa caaaagaaaa attgatatta ataggtatgc
     5461 caggtagtgg aaaaactaca attggtaaac ttttggccaa agaatataat tgtagtttct
     5521 gtgatatgga tgattatata attcaaatat ctcaaaaaag tatagcagag ttgttttcag
     5581 aaggagaaga tatctttagg aactatgaga ctcaagcatg tagagaactt tctataagtg
     5641 ataaaacagt gatatctaca ggtggaggtg taataaaaaa ggatgttaat atggaaatac
     5701 taaaagaaac aggtataata atttttattg atagacctat acaaaagatt ttggaagata
     5761 taaatattaa ttcaagacca ttattaaaaa acggaaaaga tagattgtat aatctttaca
     5821 atgagagaat aaatctttat aaaaaatttt cagatataga gattttaaat gataaatcat
     5881 taaataatgc tgtatataat attacaaatg cagtcagtga aaattttaaa tttgacttta
     5941 aagaaaaata atctaggggg aagtaaaaat aatgaatatt gttattgtag gactaggagt
     6001 tataggaggc tcttttgcta aagcattaaa aaaagctgga tatgaaaatg tatttggagt
     6061 agatgtagat ttagaaactt taaaaaaagc agaaaaagca aaaatcataa aaaaaggatg
     6121 tactacaggt aaagagttat ttaaaaaagc tgatttaatt atactatcta tatatcctag
     6181 attagttgta gattttctaa ataataataa aaactttttt aaaaaaggga ctataattac
     6241 tgatactaca ggaataaaag aaacacttat caatgatgtg ttgcaaatta ttccagatga
     6301 tatagatttt atatttggac atccaatggc aggtagggaa aaaaagggta ttgattttgc
     6361 aagtgaacaa gtttttaatg gcgcaaatta tataattact ccaactggca gaaacaacat
     6421 aaaaaattta gagttagttg aaaatttaat tttagagatt ggatttaaaa gagtaaaaaa
     6481 gttaacttca caaaaacatg atgagattat agcttttact tctcagttac ctcatgttat
     6541 ggcagttgct cttataaata gtgatgaaga aggtagagat acgggtaaat ttattggaga
     6601 tagttataga gatttaacta gaattgcaaa tatgaatgaa gacttatgga gtgaactttt
     6661 tttaggaaat agagataatt tactaaaagt tatagaaaac tttgaatcag aagtaaattt
     6721 agtaaaagaa gctatattta acaatgataa aaataaatta atagagtatt ttaaaaaatc
     6781 atcaataaga agagaagctt tagaaaaata aatattaata tttaagctat atatagatgg
     6841 gtataaatat aagcgatagt gtatttaatt gtattaataa atatggattc aatataatta
     6901 aatatgctat tgatatattt gtacccttaa ctattgttat cttttaaatg ataatgatat
     6961 ttatttaaat actctttatt aacaatttat aaaacttaat tgtaaaaaat acttattaat
     7021 agtaaaataa agtgaatcaa ttatattata attgctaaag agagtgaggt gtagctattt
     7081 gaaaaaaaat agattaatag caaagaatat atcaatagca tttatagtac tattcttttt
     7141 tagtgtattt acattctttt atgtaggtaa tattaataga gtgttagaat atgaaacaaa
     7201 tgacataata acagttacaa ttgctggatg gattatactt tcatttttat ttttaggtat
     7261 tataatttac atattatatt caaaagcaaa tagtcaaaaa actatagaaa aagtagcata
     7321 tacggatttt gtaacaggtt attccaactg gagaaagttt gaattagatg ttacaaattt
     7381 attaaagaaa acatcacaaa ataataaata tgcaatggtc atattcgata ttgataaatt
     7441 taaagcaatt aatgatatat atggccataa aaagggaaat ttaatattaa aagatattgc
     7501 agatacttta aatgaattga ctgatatcaa tgaaactttt gctcgtgtaa gtgctgataa
     7561 tttcaatata ttattaacat ataacaaaaa agaggatata ataaatatta tcaaaaagat
     7621 tatggcaaat aatgaacttg taaacttatc ttttggaatt tatgaaatca aagataagga
     7681 tttatctgta agtgtatata gtgatagagc ttcacttgca aaatcatcaa taaaaaataa
     7741 tagtgatgta aattttgcat tttttaatga caaattaaga gagaaattat tatttgaaga
     7801 taagatagaa aaagaaatgg aatatgctct tgaaagtggg caattcgtaa tgtatttaca
     7861 accaaaatac aatattaaat tagataaatt ttgtggaagt gaagccctag tcagatggca
     7921 atatacagaa aaagaggtca tatatccagg tgattttatt cctatatttg aaaaaaatgg
     7981 atttattaga aagattgata tgtacatatt agaacaagct tgtaaagaaa tccggtcttt
     8041 atttgataaa ggaatttcac ctttacctat atctgtaaac ttctcaagag ttgatttttt
     8101 taaaaaagat tttattgaaa acatagtaaa tatatgtgat agatataaaa taccatatag
     8161 tttaatagaa attgaaatta ctgaatctag tatgtttgga gatactgata ctctatttaa
     8221 tgttagtaga aatctacagg atattggctt tatagttgca atggatgatt ttggctcggg
     8281 atattcttct gtaaatatgc ttaaaaatat accattaaat gtaataaaat tagatagagg
     8341 attttttgtt gatgataaag atgttgataa gagtcaaatt gttataaaaa gcatagtttc
     8401 tctcattaag caattaggaa taagggttgt tgctgaagga attgaaacaa gaagtcaaat
     8461 agaaatgtta aaaaaagcaa attgtgatat tgttcaagga tattattttt caaaaccatt
     8521 accaattaaa gaatttgaaa aattagtcta taaaatatag tcagcgagtc ttaaatggga
     8581 ggtggtgatt aagtgataag agcaaaatcg ttaaaaaatg tactgagtat tgttttaata
     8641 tttttattta caataatttc tttttctgat tttgcattta aaactaatgt ccaggaagaa
     8701 gaaaatagta aaattaattt aagggaaata tccctacaaa gttccaatgc tataaaaata
     8761 aaattagata gttctctatc ctttattaaa agtgtggcaa atatggtttc ttattttaat
     8821 actatagata actcaaaaat agttccatta ttagctaata tatcaaaaga atctgacttt
     8881 caaagaatct ctattgtatc tcctgatgga ataagtcata ccagtgatgg caaaattatc
     8941 aatgtgtcaa agtatcagta ttttaagaaa gctattaaag gagaaagtaa tatatctgaa
     9001 gttgtgaaat ctccaattga tggaaaagat acttttgtta tagctactcc tgtatttaat
     9061 aagaataaca aaataattgg tgttttatac ggttcttact acaatgataa attagctgaa
     9121 tttatagata taacaagttt taatagtgaa gggtacatag atatatttga atctagtggt
     9181 caatttgttt taaaatcttc acatacaaac aaactgatta agtcaagtag taacatatat
     9241 gatatattta aaaaagcttc ttttgatgat ggttatagct ataaaaaaat atatgaagat
     9301 acaaaaaata acaagagtgg ctttacctca tatgaataca aaggagaaaa tcgttatgct
     9361 acttatacac ccattggtgt aaatgactgg tatgtaattt ctgtgatacc acaatatact
     9421 gtaagaagaa acattgataa aataaatcaa ttagcatttt ctcttatttt caaggtattc
     9481 ttattgttta ttatgcttat aatatatatt atttataaaa acaataaatc tcagaaagat
     9541 atactaaaag ctaacaaaga aatctcatct attacaaata gcattcctgg aggagtacaa
     9601 aagtgtaccc tgggtgaaac atgcaatatt aattttttaa gtgatggatt tatagagttg
     9661 tttggttata caagagaaga aataaaaaca ttgtttaata atgattttta tagtttaata
     9721 cataaagatg atgttgaaag aataaaaaaa gaaattttta aacaacttta caaaaataaa
     9781 actgttgaat tagaatatag gattataaca aaaaatggta atacagtatg ggttttagat
     9841 aaaggggagc ttataacaga acctgatgga aaagaatatt tttgttgtgt aactgtagat
     9901 attactagaa caaaacaatt agaacaagag atggaacaaa aaaatctaga acttgaaatg
     9961 atatcagaaa atgttttagg tggtataatt ataacagaat ttaatgatga ttttactata
    10021 aaatacgcta actctggtta tctttcaatg attggatata cacgtgaaca attagaaaat
    10081 gaacttaaat acaaagcttg taatcttgtt ttttatgaag atagaaagaa ggctcttgaa
    10141 agtatacaac atcaattaaa cacaaaagga atagctgtat atcaacatag aataagaaga
    10201 agagatggta atattatttg ggtttctata aaaggaaggc ttattgttga tgatgatggt
    10261 attgaaaaag gtatttggat tctaaatgat ataacagatt taaaaaatgc agaacaaaaa
    10321 cttaaaataa atgaagaaag atttagaatt gcattaaagc aaacatcaaa cactatattt
    10381 gagtatgata taaaaacaaa gtcactttta aatactagta aagagcttga taaatataat
    10441 atttataaaa ttactaaaaa tgttccatat tctctagtag aattaggagt tattcataaa
    10501 gattttagtg atgattttat aaatatgtat gaaaatgtaa taaatggagc aaaaaaagca
    10561 agttgtgtag ttaagatgaa acttccagat gaaaattata tatggaataa agttaccttg
    10621 actacgattt ttgatgaaga tggtaatcct gtaagagcaa ttggtataca ggaagatata
    10681 agcaaacaaa aggaagcaga gataagatac aatcaagaag gtaagtatca ttcagctata
    10741 ttgtcggaag caatgataac ttatgaaata aatgtatcaa aggatacttt tatcaaagga
    10801 aatgaaagtt ggcaaaaacc atttggaatt aagcctgaca ataactattc tcaaatggta
    10861 aaaactatag caaatagtat tgtacataaa gacaataaag aaacattttt aaatacattt
    10921 ttatgtgaaa acttattgga tgcatataaa aataatgtga ctgaaataaa attagaatat
    10981 cgaagaatga atcaagaaaa taaaatgatt tgggtcattt gtacaatgca cttaataaaa
    11041 gattctatta cgaacgatat aaaagcactt gcttatgtta aagatattga caagcaaaaa
    11101 aatgaagaaa ttagattaaa attaaaagct gaaagagata ctcttacagg attatataat
    11161 aaaggtacta cagaaaaatt gattaatgat ttcttgaact ctgaggaagc aagcttagga
    11221 atgcatgcat ttttaattgt tgatatagat aattttaaat ctgtgaacga taatttagga
    11281 catgtatttg gagataaagt attatttgaa gtttctaaaa acctaaaacc tatatttaga
    11341 aaagatgata tagtaggtag aattggtgga gatgaattta tagtattctt aaaaaatatt
    11401 cagtcttttg agaataccaa aaagaaagca gaaaaaatat gcgatatatt tagaaattct
    11461 tatacggaaa ataaaaagac atataaaata tctggaacag ttggaatttc atttgtacca
    11521 gaacatggaa ctgtatttga agaactttat aaaaaagcag acatagcact ttattatgca
    11581 aagagcaaag gaaaagataa gtatgcactt tataatgatt gtatctacca aaatggactt
    11641 gaaaataata taagtgataa taatataaaa ttagcagata aatgtgagaa atccaaacca
    11701 gtacttaaag aaattcttga ttctattgat aattatatct atatagtgaa tccaaatact
    11761 tatgaacttc tttttgtcaa taataaggtg tctcgtttgg atttagagat aaaattagga
    11821 gaaacctgtt ataaatcact attaaaatct gatagaccat gtaataattg ccctcttaac
    11881 ggattagaag aaaataagca ttcaaaattc aaaatagaga caaatacatt tggtaaaaat
    11941 atcagtatag caagttggat taattgcata gatggagaat acaactgtct tatagagtgt
    12001 atagattctt ctttatacaa aaataaataa aaaaggacta tgaagatatg ttaaatagta
    12061 taactttgat acttggtata atatttacaa tttactattt ttatctcaaa atagtttttg
    12121 gaggaatttc atttagtgag attttcttag ttgtaggaat tgtactaatt atctatcaaa
    12181 tatttaagaa aaaaattaaa gaaaagaagg ttttttatag ggtgttaaaa ataataatca
    12241 gcattttttt aatagtattt gtagttactg agagtctaat tattttttat cctaaaaata
    12301 gtttagaatc aaaaagtgat tatctcttaa ttttaggagc ttctgtaaaa aagactacac
    12361 caagtacaac cctgaagggt aggttagaca ctgcattgaa atacctaaaa attaatgata
    12421 attgttatgt ggtagtatct ggtggtaaag gaagtggaga aaaaataact gaggcaaaag
    12481 ctatgaaaga ttatcttata aaaaatggta tagataaaaa taggataata gaagaggata
    12541 aatccacgaa tacttatgag aattttaaat attcaaaatt gaagatagaa gaacatagtc
    12601 aaagaaaact aagcgattta aaagtaaaaa tagtaacaac agattttcat gttctcagaa
    12661 gtaaaatatt agcatataga aatggatata aaaatacgtc tttttatgct agtaaatcaa
    12721 aactttcatt tgtaccaact tattatacaa gagaattttt tgcattatgg aaaacaatca
    12781 tttttgatag ataataaata aaaagactag atataaactc atatctagtc ttttctattc
    12841 ccttaattct aatccatttt ccaactttac ttgttgtaga aatttcaaca ttgggattta
    12901 caagtaattg cttataagaa gttttatatt tttcgattcc aaaatataat tttccttcat
    12961 aatccattat aaatccaaat ggtcttactc ttggtttatt atcttcaact gtagcaaaat
    13021 agaatgttga gttttctttt aaaaaattca ttattttttc atgattaaat catctttgta
    13081 tcttatacta atataatgaa tataaataaa atattcatta tacttaatat aaatcgatat
    13141 aaaaacaatt acaatattat attgattatt cgaaattata tataaaattc agaaaaaaat
    13201 tggtttacat aataaaaata aagtcaacta aaattattga ttttagatta aagtaccgga
    13261 ttaagcattt aagtagattt taagcttgat ttgattagaa aggtacaaac tatcaccgaa
    13321 aaaaattaaa cccatttaaa aagcaatata aaagcttgtt atttttgaga aaaatagacc
    13381 ctctaaactc aattagataa aaataaaata cagaaaatta tatctctgaa tatctcaagt
    13441 aattaatttt aaattttacg atattttgtt tgatgattta taatataaaa gcatactctt
    13501 aatctgctca aattaaaaag aataaaaaat aacaaaaaaa tcactgacat ttcactgaca
    13561 aattgtaatt ttgttattat aaatacattg aaaatacttg attattgaaa aatggcataa
    13621 aataatacat tttatgccat ttactattat ttgatagttt ttaacttatg acataagata
    13681 ttttttaaca tatacaataa aatataaaaa aattgatatt gcaaataaaa aaaatacata
    13741 ttagatgtta tagaaaaaaa gcgcacttat aggcttaaaa tgtcacataa aagagtttta
    13801 aagaataata tattatgaac acaaattttg taatcacaaa ggagtgataa tatggcaaca
    13861 gtatcaggac aaatagtttt tgatagaaat agaagtgcta ccattgattc tggagactca
    13921 ggaatagcca atataccagt tgtattacaa gatatagcaa ctggagttag acttgtggtt
    13981 ctcacagatg catcaggaaa ttatgttttt actaatgttc caaatggtaa ctatagaatt
    14041 gtagaagctt ttggaactac aggaggagta ccaacaccag gaaattttgc aacagcgata
    14101 gtaggtccag ttccaattgc agaaatgcca cctattagtt ctgtgacaaa tcctcctatt
    14161 ggttcaacaa acttagatgg tacaacacct aacatactat taataacagt agcaggttca
    14221 gatataacaa atcaaaatat attaaatggg cctgtgattt atacacctat agagaatata
    14281 ttggattctt gcgtatctgt atctaatata aaccttatta cagatgcaga taacggaaca
    14341 ttcggttttt ttccaccagg tacaccaagt aatacaggac ctgaaataga accttaccca
    14401 aatgtgacgc cagattttac gtatgttgta ccagacccaa ctaagtttac acctttagat
    14461 ggagaatata cagtacaaaa tattatgaca aatgcaatga gtaatgttat aggagcttgg
    14521 tggcgtattg ctgaccatac tacaggaaat gaaacaggaa gaatgatggt ggtaaatggt
    14581 tttaatcctg gagctgtatt ttttaaatca acagtacaag ttacacctaa cactaattat
    14641 ttatttagca cttggatttt aaaccttttt aaggtaacag gatatccacc accacagcta
    14701 ggtgtaagaa tatttgacca aaataataat atactatatc aagcaacatt aggagctcaa
    14761 attccagtta atacaaacgc accagaatgg aaagaagtag gtactgtgat taattctcaa
    14821 aataataatc aacttacagt agaatttttt agtgaaggag aaagcgccat tggaaatgac
    14881 tatgctatag atgatgtttc tttaagagaa atagctgttc caacttttac tccaataaaa
    14941 acaagtaaca cagaaactgc taatgtaggt gatataatca catatacagt tacattagat
    15001 aatacttgtg atagcccttt aactaatgta ttttttaggg atttaattcc aaatggttta
    15061 gagtttatac ctggaactgt aacggttgat ggagtatctg taccaggagt agaccctaat
    15121 acaggtttcc cacttccaga tattggagga ggaacagggg ttgaagtaac ttttgatgtt
    15181 gtggttgaaa gtattcctaa cccaaatcct actaataata tagctaatat agattactct
    15241 tatacacctg tagaaggcgg tataccaaat gatttttcag tagattctaa tccagttcct
    15301 gttgaagtaa tctcagcaga tattgaagtt acaaaattat ctgaacctac tatagtgaat
    15361 ccaggagagg aattaatata cactataaaa gtagtaaata atggaccatt cccatctgaa
    15421 aatgtggttt taacagatga tgtaccagct tctattataa atccagagta ttcattagat
    15481 ggaggagtaa cttttcaacc atggactgga agtttaaata tagggacatt agaagtagga
    15541 gagacaagag ttattataat taggggtatt gtaaatccat caacagtagg aattataaca
    15601 aatacagctg tagtatcttc aactacagca gacccaaacc ttaataataa tacatctaca
    15661 atagagacag aagtgaattt attagcagat attttagtaa tgaaaacagc agaacctaat
    15721 tcagctgttc caggtacttt attgagatat actattcaag tagaaaactt aggaccagca
    15781 aatgctgaaa atgtaatatt aaatgatgat attccagctt ctattataaa tccagaatat
    15841 tcattggatg gaggagcaag ttttcaacca tggaatggaa gtcttaatat aggaacttta
    15901 aactctggaa tttcattaac agttttaatt caaggaacag ttagtttaaa ttcttcagaa
    15961 tatatagtaa atacagcaac agtttcttca actacacctg acccagattt aagcaacaat
    16021 atatctacca ttattacacc agttaaccca caagcaggta tttctattat aaaagtagct
    16081 gacgaggatg tagctgttcc aggagaagaa tttgtatata caattgaaat ttttaatgaa
    16141 ggaccatcta atgctacgaa tgtagtttta acagatgata taccagatgt tattttaaat
    16201 ccagaatatt cattggatgg aggagcaact ttccaaccat ggactggaag tcttaatata
    16261 ggtacagttg caccagggca attaataaga attatcataa agggattagt aagttcaact
    16321 gctacaggag atattactaa tacagcagaa gtaagtgcag atgtaccaga accagttacg
    16381 gattcatcaa cagtgacaac tcctatagtt ccatcagcag atatagaagt aataaaaact
    16441 agcaatatgg atacagcagt tccaggagaa acttttagtt atactatatt agttatacta
    16501 taacagttac aaatttagga ccatctgctg cacaaagtat cgttttgaca gatgatatac
    16561 cagatgttat tttaaatcca gagtattcat tggatggagg agtaactttc caaccatgga
    16621 ctggaagtct taatataggt acactaccag ctggaacttt aagagtgatt atattaagag
    16681 gaattataaa atcaacatgt cttgatagat taacaaatat tgcagaagtt acttcaacaa
    16741 caccagattc aaaccttaac aataatatat caagagtgca agtagaaata aaacaatgtt
    16801 gttgtaatga ttgctgttgt aacaactgta gtaattgttg ttgcaatgat tgtggttgta
    16861 aagattgttg ctgtaattgt tgtaaaaatg acttttggtg ttgattttat aaaataattt
    16921 tgtatacctt aaattaaact gaaataaaaa ataaattcac atatgagtaa aatattttat
    16981 aaatattaat aaattttcta tctttga
//
LOCUS       DAEPUT010000088        16622 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.090, whole genome shotgun sequence.
ACCESSION   DAEPUT010000088 DAEPUT010000000
VERSION     DAEPUT010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16622
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.090"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            16..714
                     /locus_tag="KRL22_003118"
     CDS             16..714
                     /locus_tag="KRL22_003118"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBH1273565.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHDLMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(934..1551)
                     /locus_tag="KRL22_003119"
     CDS             complement(934..1551)
                     /locus_tag="KRL22_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HBH1273566.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(1678..2700)
                     /gene="argF"
                     /locus_tag="KRL22_003120"
     CDS             complement(1678..2700)
                     /gene="argF"
                     /locus_tag="KRL22_003120"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBH1273567.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            complement(2809..3996)
                     /locus_tag="KRL22_003121"
     CDS             complement(2809..3996)
                     /locus_tag="KRL22_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HBH1273568.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVILKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            complement(4026..4886)
                     /gene="argB"
                     /locus_tag="KRL22_003122"
     CDS             complement(4026..4886)
                     /gene="argB"
                     /locus_tag="KRL22_003122"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBH1273569.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGEIYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKETE"
     gene            complement(4901..6118)
                     /gene="argJ"
                     /locus_tag="KRL22_003123"
     CDS             complement(4901..6118)
                     /gene="argJ"
                     /locus_tag="KRL22_003123"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HBH1273570.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            complement(6159..7193)
                     /locus_tag="KRL22_003124"
     CDS             complement(6159..7193)
                     /locus_tag="KRL22_003124"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBH1273571.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     misc_binding    complement(7447..7660)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7963..9054)
                     /gene="ytvI"
                     /locus_tag="KRL22_003125"
     CDS             complement(7963..9054)
                     /gene="ytvI"
                     /locus_tag="KRL22_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH1273572.1"
                     /translation="MNEQDHTSYQNKQRFLINFCYLVVILGLLMLLGKYAFSVLLPFV
                     FAFLIASLLNKPVLYISEKLLIKRGIVATISVFLFFLIAGIIVSVIGTYLIYGIKEIF
                     HFLPTMFEELVIPLTETVIKEVELFSGSFNFSFIELIEANMPVLMNEMSVFIVSLSNN
                     IVSGITDIVSSVPLLFMKTIITIVASIFIAIDYPTIKRFIVLQIPKNKSYLLAEAKAF
                     TIDTIIKCGFSYLLIFAITFSELYVGFAIINISYAGIIALFIALLDILPVLGTGSILI
                     PWCIISLFLGDYSMALGIALLYIVITIIRNIIEPKLVGKHMELHPVLALASMLTGLHF
                     FGFIGLFGIPLLIAFLKKLNDKEIIHILH"
     gene            complement(9069..10460)
                     /locus_tag="KRL22_003126"
                     /pseudo
     CDS             complement(9069..10460)
                     /locus_tag="KRL22_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902954.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase family protein"
     gene            complement(10479..11018)
                     /locus_tag="KRL22_003127"
     CDS             complement(10479..11018)
                     /locus_tag="KRL22_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1273573.1"
                     /translation="MSLTIQKVTSYFKDLEKFEELNNEAFPDEERMSIQEMLNLVQSK
                     KIEVSALYDKQQFIGFYVLVIENHIGYILFLAISPEQRSKGYGGKALSLMKKQYPNCQ
                     IVLDMETIEDSAPNLQQRILRKQFYLQNGFYETEYLMEYKGLEMEVLCNQKTFQKNEF
                     ETLLKNLKIREIPFHLWKK"
     gene            complement(11039..12364)
                     /locus_tag="KRL22_003128"
     CDS             complement(11039..12364)
                     /locus_tag="KRL22_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1273574.1"
                     /translation="MIQLSDNFNYKRLLKFTFPTIIMLVISSIYGVVDGYFVSNFVGK
                     TAFTAVNFIMPFLLILGCVGFLFGTGGGALIAKTMGEGKKEEANEQFSLLIVTSAGCG
                     IILAVLGIVTMPWIASAMGADGQLLTDSILYGCVVIIAIPAYILQCEFQCLFATAEKP
                     KLGLYVAIMAGITNIVLDALFITVFKWGLVGAALATAIGQYVGGIIPLLYFSRQNNSL
                     LKFKKPKFDCDVLKKTVANGSSELMTNVSTSVVSMLYNAQLLKYAGEDGVASYGVLLY
                     VALLFQAVFIGYSVGTAPIISYHYGAKNYDELKNLRKRSLIVIICFAVFMFIIGEFLS
                     KPIAFIFVGYDNNLMEMTLRAFMIYSFSFLFSGFGVFGSSFFTALNDGLTSALIAFMR
                     ILVFQVVSVLIFPIFWGVNGIWFSIVGAEILATIMTAFFIIKKQKKYHY"
     gene            complement(12361..12984)
                     /locus_tag="KRL22_003129"
     CDS             complement(12361..12984)
                     /locus_tag="KRL22_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HBH1273575.1"
                     /translation="MKIITISREFGSGGRELGKQLADILNFDYYDKEIITAIARKKKI
                     DENYVSYILENHGWRNVPLTMCTSFTNILSMQSMKTDLLIEQSNVINQIASTGKDCVI
                     VGRNADILLKKYQPFNVFVCANMNFKIQRCIEKKLNNEHISKKELEIKIREIDKNRAR
                     SREFFTSSLWGNQTSYHIIVNTSEWNIKHLSYAIANFSEYWFRRYEQ"
     gene            13076..13885
                     /locus_tag="KRL22_003130"
     CDS             13076..13885
                     /locus_tag="KRL22_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1273576.1"
                     /translation="MIKKLYKTSEFAELCGVKKHTLYHYDEIELLKPSITHENGYRYY
                     TIDQFEKFNIISVLKKAGTPLEEIKQYLNDLDTNTFLNVLHRKLMDLQEEVKKIEKMC
                     SMLRNVISTMEIHLNVNTEKIEIVNCEEEYLIATKIPEAVLTDEKTMLQGIGNHLQYC
                     LLHDYNFHVGEIVLEKNIKQGIFRESYYYSLIKNKVDDERLFIKPKGNYAVMYHQGSY
                     DSLYKTYQNMKNQLEEQGYHIVGNIYEEDLIDYLSEHNAENYIQKISIQVI"
     gene            14319..14681
                     /locus_tag="KRL22_003131"
     CDS             14319..14681
                     /locus_tag="KRL22_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273577.1"
                     /translation="MEIDYKAIGQRIKIARIKKGITQESVANIINMTPSHMSNVETGK
                     TKVSLPTLIAIANALSVSVDTLLCDNVLSSKVIFEKEAKDIFSDCDEYEIRSLVELLK
                     SAKTVIRKDREIRKQFEK"
     gene            complement(14818..14937)
                     /locus_tag="KRL22_003132"
                     /pseudo
     CDS             complement(14818..14937)
                     /locus_tag="KRL22_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393964.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(15031..15588)
                     /locus_tag="KRL22_003133"
     CDS             complement(15031..15588)
                     /locus_tag="KRL22_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1273578.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
     gene            15846..16544
                     /locus_tag="KRL22_003134"
     CDS             15846..16544
                     /locus_tag="KRL22_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1273579.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIIENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT         5685 a         2888 c         1877 g         6172 t
ORIGIN      
        1 aaggagataa tttttatgaa tgaaaaatta attggtattt tggctggaat gggtccaagg
       61 tcaacagccc cttttgttga tttaattatt gatgagtgtc aatctcaata tggagcaaaa
      121 tatgatgatg aatttccaaa gatgatgata tattcattac ctaccccatt ttatattgac
      181 cgtccaataa atcatgacct tatgaaagaa actataattg atggattaca aaagcttgaa
      241 tcaactggtg taaattttat tgcaatgcca tgcaattcag cacatatata ctttaaagaa
      301 ttaaaagagt ctattaatat accaatatta aatattgtag aagaaacagt taaaaaatta
      361 cctactatct cacaaaaagt aactcttttt tcgactagtt caacttttga gtctacaatt
      421 taccagaatg gtataataca taatggacat gaatttatat ttaaagatga atggcaaata
      481 aaattaaaca atcttattca aaatataaaa atggataaag aaaatccaca caatattgat
      541 atttggaata aacttattga agatgttaaa aatgaatcta tagaaaatat agtaattgct
      601 tgtactgatt taaatgtagt tttagaaaaa tcatatcctt caataaatat tgttgattca
      661 tcaaaatgct tggctgaatc agttgtcaat aaatatctaa aattagttaa ataaattttt
      721 catacactat attataaaaa atatatgtta taagtttatt ttaaatagta tagacttata
      781 acatatatca tagtttcttg acaatataga aattaaccat gtatttcatt atattaataa
      841 aaaggatacc aaaaatggta tccttcataa atatttatat gtttatttat aaaaataatc
      901 atatatttat tactttacta cacctaaaca atattattca agtgtattca tagagttaga
      961 aaattcttgt cctgctgtaa caagattaga taacaataca tcagctactg catcatttac
     1021 tgaacttatt atccatttat tatccttttt agaacattca aactctacat tttttgtaac
     1081 ataagtctct ttaacgcttt tttgtttttc tttcataatt gatactaaca tttcagttgt
     1141 tttctcatca gttaagtctt gtcctgaaaa actcatacca atcatctttg taaatgcctc
     1201 agctactatt tcttgaagta atggtgttga atctataaat ttacattcta ctttgattgt
     1261 agccttatca cctttaacct cgctgtcttt tattgtatat gtgattttag atgcattctg
     1321 ttttagataa tctaaaacat attgggcatt tgggtctttt gtatctaatt cctttaatat
     1381 atccttatat ttttcgtcat tattttccat taccttattc atgccttcaa agtcaaactt
     1441 tttcgcactg ttaaaaaaac tatcaattgt atcttctggt tttgcacttg aacatgctgt
     1501 taaagatatt gctaataaaa aagttgttaa agctaatatg atttttttca tatctcaaat
     1561 cctccctctt aatttgttga tacataagtt attttaacat ataatgagag tttttgaata
     1621 atatatttaa aatattttat aaattttcat taaagtaaag tctatattaa aacatatcta
     1681 tattaaatta ttgttcatat ttacatcagt catagtagaa accataacag cttttattgt
     1741 atgcattcta ttttcagctt cttcaaatac ctttgaatat tttgaattaa atacctcgtt
     1801 tgtaacctct aattctgata atccgaactt ttcataaatc tcctgagcaa ccttagtttc
     1861 taaatcatga aatgctggaa gacagtgtaa aaatataaca ttttcatttt cagttttctt
     1921 tatcatatcc atatttactt gataatcttt aagttgattt attcttgctt catattgctc
     1981 ctcttctccc atagaaaccc atacatctgt atatataaca tctgcacctt taacatcatc
     2041 aatattttca gtcaacatta tatctccttt ggatttcttg gctatttcct tcatttcctt
     2101 aaccaattct tcatttggcc aaagttcctt aggtgctagt gctacgaaat gtattcccat
     2161 tttagcacat cctatcatca gtgagttccc catattattt ctagcatcac caacatatac
     2221 aaatttaact ttattcaaat ctttatctac attttcaatt actgttaaaa aatctgccag
     2281 tatttgtgtt ggatgatatt catctgtaag tccattccaa acaggtacac cagaatattt
     2341 tgctagactt tcaactgttt cttgtttaaa gcctctaaat tctattccat catagaatct
     2401 tcctagaact tttgctgtat ctgatacaga ctctttttta cccatatgac aatcatttgg
     2461 acctagataa gttacatgtg ctccttcatc atgagctgct acttcaaatg aacatctagt
     2521 tcttgttgat gttttctcaa ataataaagc tatatttttt ccttgtagca aatcgccttt
     2581 tataccaact tttttcttag tttttaaata acttgataaa gttaataaat atctaatctc
     2641 ttcttttgta aaatccttta atgtcaaaaa actcttacct tttaaactta tattattcat
     2701 attaattcgc cccttcttat aaacttttta aattcaatta aacttgttag cactttactt
     2761 ttttatttac ttctaatttt tatctttaat caactatttt ttgaatattt agttaatttc
     2821 tagtaatata tcttttagga tttcaagagc ctcatctatt tccttataac tgattgttaa
     2881 tggtggtaaa aatctcaata cattttttcc agcagtcaaa ataagcaatc ctttttttct
     2941 agctttctct tctataatac tagattcaat attagtttca attcctatca ttagaccaat
     3001 accttttgtc tttaatataa ctttgttatt aaaactttca atagattttc ttatataatt
     3061 tcctttttct aatacttcat tataaaagcc atctttagat atctcatcta atacaactga
     3121 agctgccacc atagctaata aattacctcc aaaagttgta ccttggtctc cttttcctag
     3181 tacttttgaa agttttttat ttaccaatac tcctcctact ggtattcctg ctcccaaccc
     3241 ttttgctacg gtaactatat ctggttttac atcaaaatat tcatagccaa aaagtttacc
     3301 agttcttcct ataccgcatt ggacttcatc aaaaatcact acaatatcct tttcttgaca
     3361 tatttttact atttccaaaa cataatcttt ttcaagaaca ttaactccac cttcgccttg
     3421 aatcgcttca agaattattg cacaaactgt ggaatcaaga ttatttttta aatcttcaat
     3481 attatttctt tctatatatt taaaaccttc gggaagagga taaaaatact tatggtattt
     3541 gtccatacca gttgccatta aagacatcat tgttctacca tgaaaagagt cttttaaact
     3601 tatgatagtt cctctaccat taccatattt gtcactacta tactttcttg ctattttgaa
     3661 tgctgtttca tttgcttctg ttccagaatt acaaaaatat actttagcca ttccacttga
     3721 attaattatt ttctctcctg aatacaacac tggctcatta aaatataaat ttgaagtatg
     3781 taataattta tctacttgct cttttagagc attctttaaa ttactattac tatacccaag
     3841 agaagatact ccatatccac ttgtaaaatc tatatattta ttgccattag tatcaaaaaa
     3901 acaacttcct tcaccataat ctatgacaaa attgggttgg ttatatgtat ctataaaata
     3961 ttcattccat tttgaaattg tattgtcgtt attcattctt attctcccct cttaaactta
     4021 taattttatt cagtttcttt tcttattaat gtacctattc cactatcagt aaatagctct
     4081 gttattatag aatgtggaac tcttccatcc aaaatatgta ccctatttac tccgttattt
     4141 aaggcatcta cgcatccctc tattttaggt atcatacctc cagtaattat accttcttca
     4201 aataatttat caacatcctc taatataact tctgttatta atgatttttc ttcatctggc
     4261 tctcttaaca aaccagggac atctgtaaga agtatcaatt tatctgcatt taactcttta
     4321 gctatagcag aagctgctgt gtcaccattt atattataaa tctctccatc atctccaaca
     4381 cctatagttg caattactga aatataacct gactttagac aagattctat aagctcaaca
     4441 tttacttttt tgatttctcc tacaaatcca agttcataat ttttatatgg gtcacataaa
     4501 atcatattat tatctattcc acaaagccct actgcttttc caccttttgt atgtatttta
     4561 tttactaagt ctttattaac ctttccagca agtaccattt ttacaatttc catggtctct
     4621 tcatctgtat atctaagacc atttacaaat ttactttcta tatccacttt tgctagcatc
     4681 ttattgattt ctgcccctcc accatgtact aaaactatat tgattccaac ataactcatt
     4741 aacacaaggt cttccataac agattctttt agaccatctt ttttcattgc acttccacca
     4801 tacttaacta caatagtctt tccctgatgt ttttctatat atggtaaagc ttctataagt
     4861 gtatttgctt tttctatatt aatcattaaa gtatatcctc ctaatttcta taacttccat
     4921 ttattcttac ataatcatag cttaaatcac atccccatgc atttcctctg gcattgccca
     4981 tatttaaatc tactaatata cttatttcgt catcttcaag gatttttttt gctttttcct
     5041 cattaaaatc taatccattt ccatttttac atacttcaat atatcctttc atactctcaa
     5101 aaataatatc aactttttcc atatctattt cttcacctgc ataacctaaa gcacacagta
     5161 ttctacccca atttgcgtca gctccaaata cagctgtctt tactaatgaa gaagatataa
     5221 ctgtttttgc taattttact gcatgttctt cacttaatgc tccatttata tagcattcaa
     5281 ttagttttgt acatccttct ccatcttttg caacaagttt agcaagttct atacagacat
     5341 atgtaagtgc actcaaaaat acttgataat gttcatcttt tttgtttatt ctatcatttt
     5401 ttgcttttcc atttgctaga atcattacca tatcattagt acttgtatct ccatctacac
     5461 taactctatt aaaacttttg tcaacagcaa tttttaaagc ttcttttagc aaaactccat
     5521 caatatttgc atctgtagtt ataaatccta acgttgttgc catattagga tgtatcatgc
     5581 cagaaccttt tgccatacct ccaatagtta tttttttatc tccatacatt attgctactg
     5641 ctatttcttt ttttataata tcagttgtca taatagcttc tcttgctcca atatgacctt
     5701 gtttacttag attattcact aattcatcca tattttcttc tattaaatct atatttaatg
     5761 gctttcctat aacacctgta gatgcaacca aaacatcact ttctttaata tttaatttat
     5821 cactggtgaa tttagccatt ttataagcat ttataagtcc ttcttttcca ttaaaggtat
     5881 tagcattagc actatttact atgatagctt gtgcttttcc atttttaatg tgttcctgtg
     5941 taacataaac aggattgccc tttactttat tttgagttac tactgctgct gcatcacata
     6001 aaacatctga ataaaccaaa gctaaatctc ttttttcttt attttttctc aagccacagt
     6061 gaatccctga agcaaaaaat ccttctgaaa ctgtaactcc accctttata atctccatat
     6121 ttatcctcct aattatatga gtttagtatt ttttatttct aaaatgatgg tgcaatattt
     6181 tttaaacctg tattttcttc aataccaaat attatattca tgttttgtat agcttgacct
     6241 gctgctccct taatcatatt atctatagct gaacagatta tcaatgtatc tccattttca
     6301 tgtaatgata ttacacattt atttgagaat ctaacattct ttaaagaagc taccttatct
     6361 aatggaagaa tttctataaa ttctttaaat tcataataat cagttaattt cctatgtata
     6421 tcatttatag aaatattatc ttcttttgta caatatatag ttgataagat tcccctattt
     6481 actgggatta agtttggtgt aaaaactaca cttacttttt ctttgcagga ttcacttaaa
     6541 ttttgttcta tttctggagt atgtctgtgt ttccctattt tatatgcagt gatattttca
     6601 ttaacctccg taaagtgact actaatcgat aattctctac cagcacctgt aagacctgat
     6661 ttagaatcaa ttattatatt attatttttt atcaatttag aacttagtaa tggcatcaat
     6721 ggtaaagaaa tactagttgg ataacatcca ggatttgcaa ttatatctgc atcttttata
     6781 tcttctttgt atatttcact taatccatat acagcttttt tatgtaagat tttatctata
     6841 aaagatactc cataccattt actatatact tcttcatctt ttattctaaa gtcagcacct
     6901 aaatctataa ctttcttttt cgatttaatt gcttttatta caaacttttc actaactcca
     6961 tgtggaaggg ctgtaaatac aacatcacac atatctataa ctttttcatt ttctatacat
     7021 atcatgttat ttttatatcc tatacttgga tatatatcaa ctatatcttt tccaacatac
     7081 gaatttgaac ctatcgctgt cacttcgact ttatcatgat tcattaataa tctaatcaac
     7141 tctgccccga catatccagt tgcaccaata ataccaactt ttattttatt cattttgttc
     7201 cctccatttt tatattcaaa tagtcttaaa atcctatctt tccactttac tatatgataa
     7261 tcatttgata atacgtagat taaaatactc taattaaaac aaaaaacccc ttagcattat
     7321 aaatactaag aggcgatttt ccgcggtacc actcttattg gtaaaattac aataatcatt
     7381 aaaactcaaa ttaaaaagta tctacaaaat gtacatttaa aattaaaaaa gcctcttggt
     7441 caaagaccaa gagacgaata tacacccgcg ttaccactct aattgataag ataatcttac
     7501 ccactctaat ctcttaaggc gagattcacc aattaccata ctattacttc tggtaatctc
     7561 ctccaaagct ctattcacaa taaaattcgt tactaggctt ccaccattcc cagctctcta
     7621 tcaactagct ttatgctact ctctttttca caggatttca atttattttc ttattgtttt
     7681 atatgatagt ttattttttt aactttgtca atataatttt taaatttttg gaaatatttt
     7741 ctatataatt aatttccagc attttgtatc taaattgagt tataaatatc tacagtaata
     7801 ggacaccatg aatttcctgc tgtaatatat tttaaaaaag ttctccctct tgaatcaagt
     7861 cattcaaaag ctataccttt gtcaaaatta tttttcatcc agcgtttttt agaaaaaaca
     7921 caattttctc cataaaagag acatacatac aactattctt tcctaatgta atatatgtat
     7981 gatttctttg tcatttaact ttttcaaaaa cgcaattaac aatggaatac cgaacaaccc
     8041 aataaatcca aagaaatgta atcctgttag catactggct aaggccaata caggatgtaa
     8101 ctccatatgt ttaccaacta attttggttc aataatattc ctgataatag taatcacaat
     8161 atatagtagt gcaattccta atgccattga ataatcccct aaaaataaac tgataataca
     8221 ccaaggtatt agaatacttc cagttcctaa aacaggtagt atatctaaaa gagcaatgaa
     8281 taaagcaatt attccagcat aagaaatatt aataatagca aaaccgacat ataattcaga
     8341 aaaagtgata gcaaaaatta aaagataaga aaaaccacat ttaataatgg tatcaatagt
     8401 aaacgctttt gcttctgcta aaagataact tttattttta ggtatctgta gcactataaa
     8461 tctctttatc gttggataat caattgctat aaaaatagaa gcaacgattg taataattgt
     8521 tttcataaat agtaatggaa cagacgaaac aatatcagta ataccagata cgatattatt
     8581 tgaaagagaa actatgaaaa cactcatttc attcatcaat acaggcatat ttgcttctat
     8641 taattcaata aacgaaaaat tgaatgaacc agaaaatagt tcgacttctt ttataactgt
     8701 ttcagtcaaa ggtattacca attcctcaaa catggttggt aggaaatgaa aaatttcctt
     8761 tattccatat attagatatg tacctattac acttactatt attcctgcaa ttaaaaagaa
     8821 taaaaaaaca gatatggttg ctacaatacc tcgctttatt agtaattttt cacttatgta
     8881 taagactggt ttattcaata aacttgctat taaaaatgca aaaacaaaag gaagtaatac
     8941 agaaaacgca tatttcccta ataacattag taagcctaat atcactacca aataacagaa
     9001 atttattaaa aatctctgct tattttggta tgatgtatga tcttgttcat tcaaataaaa
     9061 tgcacctcct actttatagt aactttatat gtgccttttg gagcaacagg gggcattgtt
     9121 tcacacattc cagaacaact ttttgcttgc acaaaatatt caatcatatc acctgacttt
     9181 cctatcatat tggcaaaaaa tatttctgct tctgtagttt cttctaacat aatactttcc
     9241 catgtttgaa aaccatagta tcgataaaac agtctacaat tttcataatc taagccagct
     9301 ttactataat caactatttg aatagtaact tctaaagcat cattctctga aacgatttct
     9361 tctaatcttt tcacggaaat atagagcata ttctcatccc aaattgctct tgtcctgcaa
     9421 tgaataacat cttcatttcc ccagccagtt ctcacatatc ctgtacgatt ttttataata
     9481 tctggctctt tttcaaaatc aaactcatat cctttaattt catatccagg caaagcgttc
     9541 tgccattgtt ttattgcaat tttatcctgt tcaattccat acattggaac atagacacga
     9601 ctatttaaaa tcacagaatt aacataagca gtaagttcat cactgtcctt ttgaaacgga
     9661 acaatatcta tacgaaagat tttgaatgga cgtccatatc tggtttctac cttttttact
     9721 tcttctaaaa ttttttcata tctttcatac aaatagtgtt cttttggcgt tctgctcaca
     9781 agtaatgttt cttcatcaat tatttttaaa taacagtcaa tatgttgtaa accataatca
     9841 gcaaaattag aaaatatata atactcattc attccagtat ctcttgccac catagaaaaa
     9901 aattcttcgt cagaaattcc tttcgcacga ttttctgtct gtaaaatgtg catagacatc
     9961 aatttattga aaccatctga cataagattt ccgcctgtta gtgcataagg taatttcata
    10021 aatggcaaac caatctgttt cgcaatcaac tcttgtgatt gatcttcttt ttgttcataa
    10081 gagttagtag ttaataggtt atgttcgcaa tcaaacatga tttctggttt atttatggat
    10141 acaaatggtg ttgacatctt atattctgca ccagccaaaa agagttttcc gttttcatca
    10201 aaaatagggt gcatacccca atcacgaacc catggtgtat caaatccctg tggagcaatg
    10261 cagaaaatca aattttttaa atttccaccc cacttactta aataatattt tgcaatttca
    10321 atttcctctt tatttggtac acacatgtat acagaataat tttacgttaa atctacaata
    10381 tacttatggg gaagaaaagg gggccatgca agcatgacac ctttaatcgg ttcccattcc
    10441 ccagctaaac gtcttttcat ttctaatacc tcactttctt actttttcca caaatgaaat
    10501 ggaatttctc taattttaag atttttcaac aatgtttcaa attcattttt ttgaaaggtt
    10561 ttctgattac ataaaacttc catttctagt cccttatact ccatgagata ttctgtttca
    10621 taaaacccat tctgaagata aaattgcttc cttaaaattc tttgctgtaa attaggagca
    10681 ctgtcctcta tagtttccat atcaagaaca atttgacaat tgggatattg ttttttcata
    10741 agtgacagtg cttttccacc atatccttta gagcgttgtt ctggagaaat tgcaagaaat
    10801 aatatatatc ctatatgatt ttcaatcacc aaaacataaa aaccaataaa ttgttgctta
    10861 tcatataaag cagatacttc tattttttta ctttgaacta aattaagcat ttcttgtata
    10921 gacatacgtt cttcatctgg aaatgcctcg ttattaagtt cttcaaattt ttctaaatct
    10981 ttaaaatatg aagttacttt ttgtattgtt aagctcatat agatacctcc aaattgattt
    11041 aataatgata ttttttctgt ttttttatta taaagaaagc cgtcataata gttgccaata
    11101 tttcagcacc aacaatagaa aaccatatcc catttactcc ccagaatata gggaatataa
    11161 gtactgatac aacttgaaat actaaaatac gcataaaagc aataagcgca gaagttaaac
    11221 cgtcatttaa tgcagtaaag aaactagaac caaaaacacc aaaaccagaa aataaaaagg
    11281 aaaaagagta aatcataaat gctcttaatg tcatttccat taaattatta tcgtaaccca
    11341 caaaaataaa agcaatcggt tttgataaaa attcgcctat tataaacata aatacagcaa
    11401 aacaaataat tacaatcaaa cttctttttc ttaaattttt taattcgtca taattttttg
    11461 ctccataatg ataactgatt ataggggcag taccaacaga atacccaata aaaacagctt
    11521 gaaatagtaa cgctacataa agaagaacac cataggatgc aacgccatct tcgccagcat
    11581 attttagtaa ttgagcatta tacagcatac tcacaacaga tgtggaaaca ttagtcatta
    11641 gttctgaaga accatttgca acagtctttt tcaaaacatc acaatcaaat ttaggtttct
    11701 taaatttaag caaactgttg ttttgtcggc taaaataaag taatggaatg ataccaccaa
    11761 catattgacc gattgcagtt gccagtgctg cacctaccaa tccccattta aaaacagtga
    11821 taaataatgc gtctaaaaca atatttgtaa ttccagccat aattgcaaca tataatccaa
    11881 gttttggctt ttctgctgtt gcaaataaac actgaaattc gcactgcaaa atataggcag
    11941 gaatagcgat aattaccaca catccataaa gaatactatc tgtcaataat tgaccatctg
    12001 ctcccatagc agaagcaatc catggcatag ttactatacc taaaacagct agaataatac
    12061 cacaaccagc agaagtaaca atgagtaacg aaaactgttc gtttgcttct tctttttttc
    12121 cttcacccat tgttttagca attaaagctc caccacctgt tccaaaaaga aagccaacac
    12181 accctaagat tagcaaaaat ggcataataa aattgacagc agtaaaagca gttttcccta
    12241 caaaatttga aacaaaatat ccatcaacaa ccccataaat agaacttatt accagcataa
    12301 taattgtagg aaatgtaaat tttaataagc gtttataatt aaaattatct gacaactgta
    12361 tcattgttca tacctcctaa accaatactc tgaaaagtta gcaattgcat aagaaagatg
    12421 ttttatattc cattcagatg tattaactat aatatgatag gaagtttgat ttccccataa
    12481 ggagctcgta aaaaattctc ttgatcttgc tcgattttta tcaatctctc ttatctttat
    12541 ttctaattct ttttttgaaa tatgttcatt gtttaacttt ttttcaatac agcgttgtat
    12601 tttaaagttc atatttgcac aaacaaaaac gttaaatggc tggtacttct ttaataatat
    12661 atctgcattt ctaccaacaa taacacaatc cttacctgta ctggcaatct gattgataac
    12721 atttgattgt tctattaaca aatctgtctt catggattgc atagacaaaa tattagtaaa
    12781 agaagtacac attgttaaag gaacgtttct ccaaccatga ttttctaata tgtaggaaac
    12841 atagttttcg tcaatttttt tctttctagc tatagcagtg ataatttctt tatcgtagta
    12901 gtcaaaattt aaaatatcag caagttgttt tccaagttct cgtccaccac ttccaaactc
    12961 tcggctaatt gtaataattt tcataatatc ttttcctcac atttcattga atataaaagc
    13021 tttctatgtt atcctaaagt atctggtaac cctaaagtca ataggagatt taaaaatgat
    13081 taaaaaatta tataagacaa gtgaatttgc agaattgtgt ggggtaaaaa aacatacact
    13141 ttaccattat gatgaaattg aattattaaa accgagtatt acccatgaaa atggctatcg
    13201 gtattataca attgaccaat ttgaaaaatt taatattatt tctgtgctaa aaaaagcagg
    13261 tacaccttta gaagaaataa aacaatatct caatgattta gatacgaata cctttcttaa
    13321 tgtacttcac agaaagctaa tggatcttca agaagaagtg aagaagattg aaaaaatgtg
    13381 ttctatgttg agaaatgtca tttcaacaat ggaaatacat ctcaatgtaa acacagaaaa
    13441 aatcgaaatt gtaaattgtg aggaagaata tctgattgca actaaaattc ctgaagctgt
    13501 actaacagat gaaaaaacaa tgttacaagg tattggaaat cacttacaat attgtttatt
    13561 acatgattat aattttcatg taggagaaat tgttcttgaa aaaaatataa aacagggaat
    13621 ttttagagag agctattatt atagccttat taaaaataaa gtagatgatg agcgcctttt
    13681 tattaaacca aagggaaatt atgcagttat gtatcaccag gggagttatg acagtttata
    13741 taaaacttat caaaatatga aaaatcagtt agaagaacaa gggtatcata ttgttggaaa
    13801 tatttatgaa gaagatttaa ttgattattt atcagaacat aacgccgaaa actacattca
    13861 aaaaatttct atacaggtta tttgaaaata taaaaagcgt gtatatctca aatcacatga
    13921 gaaatacacg ccttttttaa tatctcgtat tgtctataat aatttgctta aaatgtcctt
    13981 ttttatcttc taaagttggt atcttatttc caaatttttg tagaaattca ggttcattgc
    14041 tattatttgt ttcctcaatg caaactgcat ttcctcatga atttcagata cagaaatagc
    14101 cttttatttt cgttaaccat ttaatcagtt ttttactatc tttttataaa atcttaacat
    14161 ggaggcttta tgcctccatt tcttttgtag ttgtcttaaa agtagtgcaa atttttttct
    14221 taaatatata ttatataaat tattcattta tatagagtat tatattatgc tctgtaaata
    14281 gttacaatat ttaaaagaat gaaaggagaa caaaaactat ggaaattgat tataaagcaa
    14341 tcggacagcg aattaaaatt gcaagaatta aaaaaggtat aacacaagaa tccgttgcaa
    14401 acattatcaa catgacacca tcccatatga gcaacgtgga aacaggaaaa acgaaagtca
    14461 gcctgccaac cttgattgcg attgccaatg cactttctgt atcagtcgat actctcttat
    14521 gtgataatgt actttcttcc aaagtaattt ttgaaaagga agccaaagat attttctcag
    14581 attgtgatga atatgaaatc cgttctttag ttgaactgct aaaatcagca aaaactgtaa
    14641 tccgtaaaga cagagaaatc cgcaaacaat ttgaaaaata aaaccacagc ttcaaggtat
    14701 aaattgatat gtgttgttag ctaaggtctt ttcttttttt atataatcat ttttatataa
    14761 tcaaataacc tatccaataa ttttccaatt actgtcctta tgaaatatca atttatacta
    14821 tgatacctgt gtcgcttttg tctgattatc aaggaatttt acagctacct tttcattatc
    14881 aacgacaaca gtaaaaatag ggtttaccaa ttcagaaagt aaatattctt gaaatatact
    14941 attttccttt cataaaaatg ataaaatttt attttacatc ccacgtaatg aagtgttcaa
    15001 taaataagtt aaaataattt atttacctcc ttaatcatat tttttatgaa tacctaataa
    15061 cacagtatca atagaatcga ctagaccttt tatagcttct tctttactca aaagtgattt
    15121 cccaagttgc aaagtcgaat aaccatgaag tacactcatt attaagttta atacttcacc
    15181 tgtattcttt gtatttagat tacaagaaag aataagtttt tctaataagg atttatattc
    15241 atcaaagatt tctaatgttt cattatttcc atgccaagta gcccactgaa ttgtttcata
    15301 aacaccagga ttagaaatta taaaattaaa gtatgctata cttatacact ttatagctgt
    15361 atctccaaaa tttccaatag ccgcctttat catttgacta ttcatctctc tcattccttt
    15421 atgagctact tcaagtaata aatcatctaa actttctata tgattgtaca aagatggtgt
    15481 acgtattcct agcttttctg caataacttt taaagaaact ttgttaagcc catctttatt
    15541 aactatatct gatgtagctt gtataactat ttctctacta acacgcatga ttttccctct
    15601 ttcatttaaa attaattact ttattagttt agctaatcta attagtttcg tcaattattg
    15661 taatttataa aattctttat actattataa aatcttgaca gtttaattat aatttaatat
    15721 aatactaatt gaattagttt taatactaat ataattagta ttatattaaa ttctatatta
    15781 caacattatt ttatagtttg attaatttaa caatcactaa tatatcaaac tgaaaggaga
    15841 tttttatgga aaaaaaatat ttcgaaattc atggagttcc ttcaatcctt tggggaaatc
    15901 cttcaagtaa attatatatt tacatacatg gacaatgtgg caataaagag gaggctgaag
    15961 cttttgctaa tattgcagtt ccacatgagt gtcaagtttt aagtgttgat ttgcctgaac
    16021 atggagaacg taaaagagaa aaaaattcat ttaacccatg gcatgttgtt ccagaattag
    16081 tatctattat ggaatatgca aagtgccact ggaatcaaat ttcgttatat gcaaatagca
    16141 ttggagcatg gtttagtatg ttaagctttg aaaaagagaa cttaagagag tgtatttttg
    16201 tatctccaat tctagatatg caacagctca tttcaaatat gatgctttgg gcaaatgtat
    16261 cagaagaaca gcttaaacat gaactaatta tcccaacttc atttgggcat actctttcat
    16321 gggaatatct acaatatgta aaacaacatc ctatcactca atggaatgta ccaacaaaaa
    16381 tattatatgg taaacatgat gaacttactg aaatcggtgt tgtagagaaa tttgtagaaa
    16441 agtttaattg caaccttact attatagaaa atggcaaaca ttggtttaac acaccacaag
    16501 aattaaattc attatatgaa tggttaaata ctttagttaa ataaaaaata attatattat
    16561 taatatgatt aaattattta taaatgttat ttaattaatt ttattttagc attattaaaa
    16621 ta
//
LOCUS       DAEPUT010000089        16528 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.091, whole genome shotgun sequence.
ACCESSION   DAEPUT010000089 DAEPUT010000000
VERSION     DAEPUT010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16528
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.091"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(137..1351)
                     /gene="dpaL"
                     /locus_tag="KRL22_003135"
     CDS             complement(137..1351)
                     /gene="dpaL"
                     /locus_tag="KRL22_003135"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH1273580.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            complement(2010..2549)
                     /locus_tag="KRL22_003136"
     CDS             complement(2010..2549)
                     /locus_tag="KRL22_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="HBH1273581.1"
                     /translation="MQYAIELYYDKKTEKQLFDLSKKIADEKISTKYLEWKTRPHLTL
                     ACFNDVDEACCIDKLKGFAQNHKVIPAYIGSVGMFNDTKTVFVSPIMNSSMYQFQREL
                     YEVLQDFDSNGWEWYHPNRWVPHCTIALTGDDESEAFFRASDVLLREFKKISGEFVSI
                     GLVKITFPVEEIFTVNMNR"
     gene            complement(2626..4431)
                     /locus_tag="KRL22_003137"
     CDS             complement(2626..4431)
                     /locus_tag="KRL22_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1273582.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            complement(4827..5204)
                     /locus_tag="KRL22_003138"
     CDS             complement(4827..5204)
                     /locus_tag="KRL22_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH1273583.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            6109..6594
                     /locus_tag="KRL22_003139"
     CDS             6109..6594
                     /locus_tag="KRL22_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273584.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            complement(6794..7333)
                     /locus_tag="KRL22_003140"
     CDS             complement(6794..7333)
                     /locus_tag="KRL22_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1273585.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIEADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(7326..7739)
                     /locus_tag="KRL22_003141"
     CDS             complement(7326..7739)
                     /locus_tag="KRL22_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1273586.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            complement(7775..8896)
                     /locus_tag="KRL22_003142"
     CDS             complement(7775..8896)
                     /locus_tag="KRL22_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH1273587.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            9495..11147
                     /locus_tag="KRL22_003143"
     CDS             9495..11147
                     /locus_tag="KRL22_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HBH1273588.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKIENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAIPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            complement(11500..12426)
                     /locus_tag="KRL22_003144"
     CDS             complement(11500..12426)
                     /locus_tag="KRL22_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH1273589.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRDELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTENSTYKNPESIHEII
                     IRKLNNESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            12953..13267
                     /locus_tag="KRL22_003145"
     CDS             12953..13267
                     /locus_tag="KRL22_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1273590.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            13283..13669
                     /locus_tag="KRL22_003146"
     CDS             13283..13669
                     /locus_tag="KRL22_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1273591.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            13698..15083
                     /locus_tag="KRL22_003147"
     CDS             13698..15083
                     /locus_tag="KRL22_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBH1273592.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            15086..15238
                     /locus_tag="KRL22_003148"
     CDS             15086..15238
                     /locus_tag="KRL22_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1273593.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            15261..16466
                     /locus_tag="KRL22_003149"
     CDS             15261..16466
                     /locus_tag="KRL22_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBH1273594.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
BASE COUNT         5549 a         2798 c         2242 g         5939 t
ORIGIN      
        1 tttgctttac tttttcattt atttagattt ttcatttgtt ttagttttta ttttatttaa
       61 atttttcact tatttaagtt tttattttcc ttaaattttt catttatttg ttaagttttt
      121 cttttcctta agtcttttat ttactttggc attcaccatt ccaaactata tctctatatt
      181 tatcagggtc agtatctcct tctgtactta ttaataatac tttagagttc tcatctagtt
      241 tcaaagcttc tcttaagtct tttaaatctt cactttcaag gattgaaact aatgctccag
      301 ttgtaactgc tccagattct ccagagatta ctttctcatc tcctcttaga gggtttccta
      361 atattctcat acctttagca gatacccagt ctggtgctga aacgaatgct gatgaataat
      421 tttttaacac ttcaaaacct atagtgtttg gttctccaca agcaagccct gccattatag
      481 ttggcatatc tcctccaaca aatcttggtt ttccatctcc agcttctgct gatttatagt
      541 aacaatcagc ctcatcagcc tctactacta ctgttattgg gcattcatca tatattgaag
      601 caacataccc ttgaactgca ccagcaagtg aaccaactcc tgcttgaaca aatacgtgtg
      661 ttggtctatc tactccatat tcttttaatt gttctatagc ttctttagcc atagttccat
      721 atccttgcat tatccatgct ggtatttctt catatccgtc ccatgctgta tcttgaacca
      781 ttactccatg gtcatcagct tctgcataat cattagctaa tcttactgca tcatcatagt
      841 ttaagtctgt tatactagca tctgcacctt ctcctttgat tttatttaat ctaaattcag
      901 aagaaccttt tggcattaat acaacagatt tttgacctaa tttattagct gtccaagcaa
      961 ctcctctacc atgatttcca tctgtagctg taaagaaagt tatttctcct aatttttctt
     1021 ttatttcttt tgaagttaat ttatcatacc ctaactcaga tatatctgta tctaatcttt
     1081 gagctaagta tctacccata gagtaagaac cacctaaaac tttaaatgca tttaaaccaa
     1141 atctataaga ttcgtcttta acatatattc cgcttacgcc tagtgatttt gctaagttat
     1201 ctaatttaac taaaggagtc ttttcatatt gtggaaagct ctcatgaaaa gctttagcct
     1261 ttgcaatctc ttcatctttt aaaaattcaa ttcctttttc tttttcctct gatttaggta
     1321 agttatttaa tttccatttt atttctctca tttattttat attccccttt caaatttttc
     1381 ggtgtcattt taatttttta tctttgtgcc ttatagcaaa gcaattaccg tgccaatatt
     1441 atttattcta aaaacaattt ttttatgttg gaattacata cttttataaa atttctttaa
     1501 agtttataaa ttttgagtgt gaaaaataag atttataaaa gaaaaaattc tcatattggg
     1561 aaatttttat caatacgaga attatcaatt cgagaaatcg tttatttatc ttaattcttc
     1621 ctttattatg ctcttatttt ttatatgtct attgttttgt cagatatatt actactttta
     1681 ttttctataa atatatggct ataaccttct tacgcataaa ctctataaat ttatatactt
     1741 tatattcttt attacccaaa tattctttat tacccaaata ttctttatta cccaaatatt
     1801 ctttattacc caaagcctcc aaaatggctt aaatcttttc atagcttctt acagaagttt
     1861 acatggtcgt ccccccaata agcaaaagtg caatatgtgt accattgtgc cctacttgcg
     1921 actattgagc tgtcgaaatt cgcaacttcg catttatctg atgaaatgca ctatacaaaa
     1981 tattcataac atccacaaca gagttaaagt tacctattca tattcactgt aaaaatttct
     2041 tccacaggaa atgtaatttt aaccaatcct attgagacaa actcaccact tatttttttg
     2101 aactcacgca gtaatacatc acttgcccga aaaaaagcct cactttcatc atctccagta
     2161 agtgctattg tgcaatgggg tacccaacga ttggggtggt accattccca accatttgaa
     2221 tcaaaatctt gtagtacctc atataattct ctctgaaact gatacatact gctattcatt
     2281 ataggtgata caaacaccgt tttagtatca ttaaacatgc ctactgaacc aatgtaagca
     2341 ggtattacct tatggttttg tgcaaacccc tttagcttgt ctatgcaaca agcctcatcc
     2401 acatcattga aacaagccaa agtaagatga ggtcttgttt tccattctaa gtacttcgta
     2461 ctaatttttt catcagcgat ttttttagat aaatcaaaaa gctgcttttc cgttttttta
     2521 tcataatata gctctatcgc atattgcata ataacacctc caccataaag taaaaatacc
     2581 tatctataaa aacacacaaa tacctatcat tttaatatta tattactact gttcctcttc
     2641 caattttcta tatagtgtag ccaaacctat gcctaagtct tttgctatct tcttcttcgt
     2701 ctttgtatct cttccatact tattcaacaa cttgtttatg taagtcaact ctaattcttt
     2761 aattgaaagt atcctttctt gattctctac tatccctcca actatatcat cttcaaatat
     2821 tatatttaca tccttatttt tataaatatt tccattaata ttataatagt ttaaaatatc
     2881 taatggaagc atatctttat atattattcc atcatctcca accaaattca tcatatattc
     2941 aactgcattt tccagttccc ttatatttcc cggccaatta tagttaatca acatattcat
     3001 tacattttct tctattttat ttaactgaat acctaattct aaagaatatt tagaagcaaa
     3061 cttcatcatt attgcctcaa tatcatcctt tctttcccta agaggtggca aatttatagg
     3121 aattacattc aatctatagt ataaatcatc cctaaactta ccttcattta ctaatttcaa
     3181 taagttttta tttgtagcag caatcactct tatatctaaa tctataagtt tatttgaccc
     3241 aattctcgca aattttctct cttgtaaaac tctaagtaac tttgcttgta aaggcattga
     3301 caaatctcct atttcatcaa gaaatataac accttcattt gcaagttcaa atttacctac
     3361 tttacctcca ctactagctc cactaaatgc accttttata tagccaaata gctcactttc
     3421 aaggagattt tctggaatag cagcacagtt tatcgcaata aatggcttgt tccatctgct
     3481 accttcagca tgtatagccc tagcaattag ctctttaccc gtaccacttt ccccagttat
     3541 aagtacagtt gaatttgact ttgctaattt cttagttctc tcttttactt ttaacattgc
     3601 ttctgaattt ccaattatag actctatatc actatttccc cagccactat tcacttttcc
     3661 atgtccttta tgattgatat atgtcttgtc aaatattatt attttgtcgt attgatttat
     3721 atatggatat accggaatta ttttggcatt tatattataa attttattat caatatcaat
     3781 ttctagtaat tcatgtccat ttgaggaaga ttcaacagat actatattta ctatattttc
     3841 tattatattt ttatctatat ctaatttttt tagagctata ttgtttatat aagatatttt
     3901 gctatttatg tctagtatta taacgccttt ttcaacattt tcaatgattt ctatcatcat
     3961 atccattttt ctactgctat tttttgacgc ttcatgttct tctattttca tagaaattaa
     4021 atcgcatata tgattgacaa attttaaata attatctatt tttgcactta tttctacttt
     4081 tttagtttta tctgtactaa tagcaccaat tactcctata gttcgattat tatactttat
     4141 tggaactgct attattactt tatttaggca tttcatgtaa tgggaacatt ctatacaaag
     4201 ctgattatca catatatcca atacgactaa ttcctgacct gtctgtataa cattgtcata
     4261 aataaatcct tctgtaacaa cgctttcatt tatctttgat ttatacagac ctgtaccact
     4321 aattcttatt aatctatcgt caactatttc aatatctaca tctaacacac tagctactgt
     4381 ttcagtgtat tttatcattt cttgttgaaa ttcttttaat ttacttaaca tagtttcccc
     4441 cattagaatt taatttacca aattatcagt ttagctatat tttaacatat agtcactctt
     4501 taaaatatat ataaaacatt acttatttat atatttgcgt taaaacagac aatattaatt
     4561 tataaaaagt ttgttttata tagtaacctt aattataata tgcagacaat aaaataaatc
     4621 acaatacaat aataaaaaaa agctttcctc atataacaaa tatatttttg acataaaaat
     4681 atacattata tgagaaaagc tcaatagtta aatatttaga tagattttta tatagacttt
     4741 tttaatataa acttttttaa ttgtagactt tttttattag tttttaattt ttattagttt
     4801 tgttattggt tttattgtta taatacttat aatactgcca ttgcttcaat ttctaaaact
     4861 gcatcttttg gtaattgagc aacttgtacg catgaccttg ctggtggatt ttctttaaaa
     4921 tatgtagcat atacttcatt aatatcatta aaatccttta aatcttttac gaatactgta
     4981 gtcttaaata ttttatccat acttgtacca gcttgttcta atattgcttt tacattatct
     5041 aaagaagctt ttgttgcttc ttttgggtca gatactaact cgccagtctt catatctatt
     5101 ggaagttgac ctgatgtaga aactatgttt ccaacttgaa ttgcttgaga atatggtcca
     5161 attgctcctg gagctttctc tgtagctatt actacttttg acatgacttc acctcctatt
     5221 attaagttat atttacagga aaataaaatt tcctaaacac caatattaat acgaaccttt
     5281 agactaaatt tcaaatctaa aacttcaaat aatcaatact tagatgatta tgtttatttg
     5341 tgtcttgtta acttttatta aagcaattaa cgtgccaaac tttatttata tataaaattt
     5401 tgtgaagtca ttcaaaatag ttacttctga attttttcgt aaaaaaacgc tctaaaatta
     5461 cttttttatg atgtcaattt ttttctcata tctagaaatt taccaacatg agaattcttg
     5521 ttttgagaat ttacagatta aagttatttt ttaaccttaa attctgaacc tcccatgact
     5581 aaagtcacag ggttcctgct tcatagaatt ttgcataatc aagttattac atatgaaaga
     5641 actatagttg acaatcccac tattataaat aataaaacct ttacccatac cttatttacc
     5701 ctagttatca tagagcctat tgaaaatata acagctaaat ataataataa ccaaaaaatt
     5761 atcaatatct accactgttg ctgaaaatcc aaaaaactac cttttgatag tattacttaa
     5821 caatctaatt aatctcataa taaatttaca acttataaat aaattgttat attggccgta
     5881 tctcaacaac tttctccttt cctagtttta aatcttttat agaattgtac cacgtctaag
     5941 taaattttca tactattaag tcttatttct aataaatcat tagctctcat tctatgccca
     6001 ataatgtaag attgcagtaa ttttattgat tttaatagtt ttatttaata tacttatatt
     6061 aattattttc atatgaaatt attatttata tagggggatt tttttaatat gagcaaaagt
     6121 gaattaacag cagaaacaac agaagaaatg ttagaagtac taagtggtaa agattatgat
     6181 attgcatgtc atttacatga acttggtaaa tcattagatt gtaaaattga accaaaaaca
     6241 ggtgctcgtt cttacaaaat agtatattca actaagaaac caaaacgtag cttatttact
     6301 attgaatgta atgaaaaaaa atggagagtt aaagcaaatc tttttcatct aaatacatat
     6361 aaagatgctg tggaggaatg ctctaaaact attaaagata gtataactaa aactcgtact
     6421 tgtaagaaat gtaattcaaa gtgtattgga ggttcttcgt ttgaattaga tggaaagtct
     6481 tacctgactt gcataggaag tggtcattat tttgcaaata tggaagaaat ggattggaaa
     6541 aacctagaaa aattaattac taaagaaaat aatattatgc aggaatctgt atagtttttt
     6601 aagggtaatt attaaaatat atgagcaaca acagatactt aaataggcat aaaaaaataa
     6661 agggtataat aaggatatag aataaaaata aatgatatag cacaaagagg ctgtctcaaa
     6721 atacagataa gcctcttttt attgttgaaa tgataagaat atattcaatt ttatacaatt
     6781 ttatacaaac atactacgcc aacttaccca tttcatatgc ctgtttcatt gccttacttc
     6841 ccttaatatc acctacattc caagcaccta caccatatac tatacctttt tccttagaac
     6901 catttagaca tgatgtaaat cctctaaatc cttctattgt tctttccata tcagccacat
     6961 tttcatctgc tgctgtaacg ataaaataga aatctttatc acaaatttca gtatatctag
     7021 agcaagttct atcaatcata gttttcattt gcgcattcat agtataaaaa taaactggag
     7081 tcgctaaaac aatcacatct gcctcaatca ttttttcaag aatttctccc atgtcatctg
     7141 tctgtgaaca atttgcttct ttttcataac aagcaccaca tccagtacaa tagttaatat
     7201 ctttatcttt taaaaatatc ttctccactt gatttttaga ttctaatacc ccttgtataa
     7261 actggtcaca caataaatca gaatttccac cttttctagg actagctgat actattaata
     7321 catttttact cataagatac tgcctccatt ttcttatttc tactgctctt taatactttt
     7381 tctttctcaa taataccttc ttcatatcta tcaatcttaa aatttaatcg ttccaaagtt
     7441 ttttgcattt cttctattct ttttgctagt tggtttctct gctctattaa aagttctttt
     7501 ctagctttga tagtactgct cccttgttga aacatagcta catactcaat taatgtctca
     7561 atagaaagac ctgcacctct catacacttt atgaaattaa cccactcaca atcttcttct
     7621 gtaaaagacc taattccact tttatttcta tttacaggtg gtattaaacc aattcgttca
     7681 taatatcgta aagtatccgc tgaaagctcg tattttttac taacttctga aatcgtcata
     7741 catatcttct cctcttgata ttgtatagat tgaattattt ctcaaaggtt tctgctacat
     7801 tctttaaagc atctataatt ttaatgtgtt gaggacagct ttcttcacat tgtttacatt
     7861 caatacaatc tgaggccttt ccataagttt tagtataatt attatagtag accatctgtg
     7921 ttgaaaatcc agtattaaga gcttgttttt ctgcattgta caacgcaaaa tagtttggaa
     7981 tagcgatatt ttttggacag ccttctacac aatactgaca ggcagtacaa ggaactaaaa
     8041 ttgattcgtt gataatctct actgcttcat ctataatatt atattcctct tgtacgaatg
     8101 gtttgaaatt ttgcatatat cctgtattgt ctaataattg ttccatattt gacatcccac
     8161 ttaagaccat cataacatta tctttacttg ctgcaaaacg tattgcccaa gatgaaattg
     8221 acatatctgg attgtagtca ttcaataatt tctctgcttt ttctggtatc tttgcaagtg
     8281 tacctccttt tactggctcc ataacaatta caggcttatt atgcttctct gccacctcgt
     8341 agcattttct agattgtatg ctttcattat cccaatctaa ataattaatc tgtaattgca
     8401 cgaagtctac ttctggatgc tcactcaaga ctttatccaa taattctgca ctatcatgaa
     8461 aagaaaaacc aatattcttt atttttcctt cttttttctt ttcttcaata aacttaaagc
     8521 tatcaaattt tttagctact tcataatgtg acacgcctat attgtgtaaa agatagtagt
     8581 caaaatagtc tacaccacat ttttctaatt gctcattaaa aatggtttct tgctcttctt
     8641 ttttctttaa agccattaat ggaagttttg tagctatagt aaaactctct cttttgtgtc
     8701 tttttactag agattctcta agtgctatct cactttttcc catgtgatac acataggctg
     8761 tatcaaaata tgtaaatccc ctttctaaaa aagtgtctac cattttattt aaatgttcca
     8821 tatcaatagt tgtaacatca ttttcatctt ttattggtaa acgcattaat ccaaatccta
     8881 atttttttgc ctccattgtt ttacttcccc ctttaaaact tgtttgtttt ttctctctac
     8941 tttaactatt cttacaagta tataattctt gtataattat actttactac ttggagttaa
     9001 cttcaagtca atagattttt ttatttttaa gacaaatatt ataaaaatac agttctttaa
     9061 tattaatcca ttacatgttt ctttcaccct ccaattctca aacttcacaa actccaacat
     9121 gtaaagaaat atatacttta agaaattcag tccattaata ttactacaaa tactttttag
     9181 atatgtttaa aaagaaattt cacctaaaat gtttataaaa gatttagaaa taggtcttgt
     9241 gtctatttta aaatatataa aacagtggta aagacttatt tataagataa aaaatgaata
     9301 gtgtataccc tttttaaaaa gttttttcct ttttatattt gtgatacaat gttaaatata
     9361 aaaaggaaaa ttttgtatta aagaaatctt atttgttgat tttgtaactt caaactcagt
     9421 atcaatttga ttttaagatt atattttatt aagtatgcta aataacaaat ttttaaagat
     9481 tgtgaggtaa aaatatgaat aagaaaaatt tagctatatt aatatcaggt atgatgtttt
     9541 tttctagttc ttcagcaatt tttgcagaca atactacaaa gcaagaaaga ttaataggta
     9601 aaacaagata tgaaacagca gtagaagtaa gtaaattggg atgggttcaa tcaaaaacag
     9661 ccattatagt taatggtaat tctattcaaa gtgcgctttg tgcaaatcca tttgctaagc
     9721 taaagaatgc acctatactt ttagtaaaca acaacagtat tgaaaattca actaaggctg
     9781 agcttaaaag gcttggtgta gataatgtgt acattgtaga tagtggaaat agcatttctt
     9841 ctaaagtaga aaatgaaata aaatcactta acataaaaat aaataaaata gtaggaaaca
     9901 atatatatga aatgtctaca aatgtactta aagaaataga taagataaaa aagatagaaa
     9961 atgttgcagt tgtaaatgga ctaaagggac tatctgatgc agttagtata gcttctccag
    10021 cagcaataca taatatgcct ataatattag tatcagatga aaacagcaat gatagtagta
    10081 taaatttctt aaacaatagg tctataaaaa aatcttacat agttggagga aataagattt
    10141 tatcagacaa tacagtaaag aaatatccaa acagagaaag aatcagtggt tcagatagaa
    10201 acaatactaa tgcaaaaatt attgataaat tttataaaga taaaaaaata aataatgtat
    10261 ttgtagctaa agatggtatt aaccaagaaa atgcattagt agattcatta tcaataggag
    10321 tactagctgc taaagaaaat tctcctataa tgatatctaa tggtagcctt gtaaatagtc
    10381 aaaaagaatt tattaaaaat aaagatatag atgaaataac acaagtagga ggaggatata
    10441 atcaaaaagc atttgaagat attttaaaac taaaaaatgt gaacataaga aataaaacta
    10501 aaaaaatatc tttaatacag gctaaagaaa tattaaaaca agctcttcca ggaagcaata
    10561 ttttagtttg ttattatgat gaagatgata atgaatatga ctgcaaagtt ataaaggata
    10621 atatcctata tgagatagaa attgatgcct actctggtaa aataatagaa attgaaaaag
    10681 atgatgactt aaatgataat aatttaggta cacaaaatat atcattggat aaagctaagt
    10741 ctatagcatt agatgctatt cctaatggta atttaatcta ttgtaaatat gatgctgaag
    10801 ataacgaata tgaggctaaa gtaataaaaa ataagaaaac atatgaatta gagataagtg
    10861 catttgatgg aagaattgta gatattgaca tggacaatga ttctgatgat gactttgatg
    10921 ataatgataa gaataactct aatactaatg acaacagttc tattattagt gctgaaaaag
    10981 ctaaatcaat aatgctagat aaagtgcctg gtgggaaaat agtaaaattt aagtatgatg
    11041 aagatgacaa agaatatgaa ggtgaaataa taaaaggaaa aactgaatat gagataacaa
    11101 ttaatgcaat tactggtaaa atattagaat ttgaaataga tgattaataa aaaatatata
    11161 ttctattaat tattacaagc aataaagcca taaatattga atttttcaat atttatggct
    11221 ttattttatt tttttaattt aaatccacat tatgccatta tatatatcta tgcactcttg
    11281 taaaatgggt tatatttctc cagtatatta aaaaaagaga gtgtctcaaa atgaattttc
    11341 tagctcataa ggcactctcc tttgtattaa atcaaatata ttttcatcat ttaaacaatt
    11401 aagaagaggc ttctctctat tttgagacaa ctccatttta atacactatt tatattcata
    11461 tataaacata ttttaaacaa ctaaaaagca actaatatct caatacatat cttcataaca
    11521 catatcacca taattacaag cagataaaga actctcctca tttaaatacg actcaaattc
    11581 atacccaaac agaattgttg gttctatata tatttccata tctgtatatc tccatcttct
    11641 tacctttgcc tctataacct tgtaaaaatc ttctaaacta tacccttctt ttaatctttt
    11701 atctataagt gccttagtta tactcaaatc agctttaaaa ttttttcctg attcattatt
    11761 taattttctt ataataattt catgtatgct ttctggattt ttataagtag aattttcagt
    11821 caaatcttca tccgaatttt caaaggtatt tttatttaaa ttctttttat ttaaattatt
    11881 ttttaataat tcttttttct ttgtctcatt ttctgtttca tacccagtat gaattatcaa
    11941 atcataatct ttgtctatac tctcttgatt tatacggctg tatatgttgg tattactgtt
    12001 cttaaacaac tcatctctat gtttatattt cattgttttt tggttattgt taatagttgc
    12061 atcaatgtat ttctctatat ttttgaaaat atcaccattc tttgttacaa tttctgcatt
    12121 actactttca gaacaaacat aactatatac agaacaacaa tttcccttta ctcccctact
    12181 tattaatctc aatataccta aatctataaa ttcatttaca agtctactta ttgtagatat
    12241 agatacatca aggtcagatg cagctttcct tactgtcatc ataaattgtc ctcttggcag
    12301 agttcctttt aatctttgta tattttcttt tctcattaca tagtgattaa accttattct
    12361 atttacatct cttttttcat taaaatataa tactgctgaa tttaattgat aaaaactatt
    12421 actcatattc ccactcctcc aatttaaata gataatttgt tgtaaagttt ttagattttt
    12481 aaataactta ttaaatgatt atttttatta aaaagtattc tttgatattt tcattttaaa
    12541 gttttaagta taataagtta atagtgtaga tttaactttt ttatttaaac aataaactta
    12601 atattatttt tatactaaaa atagcataaa aatctagtta tccgcataaa aactggactt
    12661 atcacacttt atcaaggtca aaaccactca atttactact aatttactac ttatgaatga
    12721 gctttgatac gacgatttat ccttgaaaag tgaagatata aagatacttc caataaaatt
    12781 tgaatattta ataggtagac acttcaaaaa atgaggtgtc tattttttta cccgattttg
    12841 aaaggaagtg aacttatgaa aacaaaaaat caagaatcaa aaggtcgttc cccactcttt
    12901 aagaccatca aacattcatt cagccaataa aaaagaaagg ataggtaaaa atatggaact
    12961 taaatttgtg attcccaaca tggaaaaaac attcggcaat ttagaatttg ctggcgagga
    13021 taaagtcgtt cagcgaagaa tcaacggacg gctaactgtc ttatcaagaa gctataatct
    13081 ctattctgat gttcaaagag cagatgatat tgtggtggtg cttcctgctg aagctggcga
    13141 aaaacatttc ggctttgagg aacgtgtgaa gttagtcaat ccacgtatta ccgcagaggg
    13201 ctacaaaatc ggcactcgtg gttttacaaa ttacctttta catgctgacg acatgataaa
    13261 agaataaaga aagagaggaa aaatgatgag attagcaaat ggcattgtat tagataaaga
    13321 cacgactttt ggagaattga aattctctgc tctacgtcgt gaagtgagaa tccaaaatga
    13381 agacgggtcg gtttcagatg aaatcaagga acgtacctat gacttaaaat ccaaaggaca
    13441 aggacgcatg attcaagtaa gtattcctgc cagcgtgcct ttgaaagagt ttgattataa
    13501 cgcacgggtg gaacttatca atcccattgc ggacaccgtt gctactgcca cctatcaagg
    13561 agcagatgtt gactggtata tcaaggcaga cgatattgtg ctgacaaagg attctagttc
    13621 attcaaagct caaccacaag caaagaaaga accgacacaa gacaaatagt cgctaggtag
    13681 aaaggagact ttttcgcatg aaacagcgtg gtaaaaggat tcgcccatct ggtaaagatt
    13741 tagtctttca ttttacgata gcgtcactcc tgcctgtttt cctgctggtt gtcggactgt
    13801 ttcatgtgaa gacaatccag cagatcaact ggcaggattt taacctatca caagcagata
    13861 agattgacat tccctattta attatcagtt tcagtgtcgc aattcttatc tgcttgctgg
    13921 tagcgtttgt attcaaacgg gttcgctatg atacggttaa acaactttac caccgtcaaa
    13981 aactggcaaa gatgatactt gaaaacaagt ggtatgaatc tgaacaggtc aaaacagagg
    14041 gtttctttaa agatagtgct ggtcgtacaa aggaaaagat aacctacttc cctaaaatgt
    14101 attatcgact taaaaatggc ttgatacaga tacgggtgga aatcacgctg ggaaaatatc
    14161 aagaccaact cttacacttg gaaaagaaat tagagagtgg cttgtactgt gagctgacgg
    14221 ataaagagtt aaaggattcc tatgtggaat atactttgct ctatgacacc atagccagtc
    14281 gtatttctat tgatgaagta gaagctaaag atggtaaact tcgcttaatg aaaaacgtat
    14341 ggtgggaata tgataagctc cctcatatgt tgattgctgg tggtacaggt ggcggtaaaa
    14401 cttactttat actgacactg attgaagcct tgcttcatac agattcaaaa ctgtatattc
    14461 ttgacccgaa aaatgctgat cttgcggact taggttctgt gatggcaaat gtctactata
    14521 gaaaagaaga cttgctttct tgcattgaaa cattctatga agaaatgatg aaacgtagtg
    14581 aggaaatgaa gcagatgaag aactataaga ctggcaaaaa ttatgcttac ttaggtctcc
    14641 cggcacactt cttaatcttt gatgaatacg tcgctttcat ggaaatgctg ggaacaaaag
    14701 aaaacaccgc agttatgaat aagctgaaac agattgtcat gttaggtcgt caagctggct
    14761 tctttctaat actggcttgt caacgtccag acgcaaaata tttaggcgac ggaatccgtg
    14821 atcagtttaa tttcagagtg gctttaggtc gtatgtctga aatgggctat ggcatgatgt
    14881 ttggcagtga cgtacaaaag gatttcttct taaagcgaat caaaggtcgt ggctatgttg
    14941 atgtaggaac aagtgtcata tcagagtttt atactcccct tgtaccaaaa ggatatgatt
    15001 tcttggagga aattaaaaag ttatccaaca gcagacagtc cacgcaggcg acgtgcgaag
    15061 cggaagtcgc aggtgtggac tgatcttgct ggctggtgtg gcaatagcca cgccagcact
    15121 taaccccccg tatctaacag gggggtacaa atcgacagga aacagtcaaa aaaacattag
    15181 aaaatccttt ggttacaagg gatttacaaa atttcagcgt atgtcaaatg ggctttaaaa
    15241 gttgacatac gcctttttga ttggagggat ttttactgaa tgaacaaact tggttacagc
    15301 atttaaaaga aaaacgcttg gcttatggac tatctcaaaa ccgtttagct gttgcgactg
    15361 gtattacaag gcagtatcta agcgatattg aaacaggaaa agtcaagcca tcagaggatt
    15421 tacagcagtc cctttgggaa gctctggaac gcttcaatcc cgacgctccc cttgaaatgc
    15481 tgtttgatta tgtaagaatt cgctttccga caacagacgt acagcaggtg gtcgaaaaca
    15541 tcttacaact gaaactgtcc tattttcttc atgaggacta tggtttctat tcttattcag
    15601 agcattatgc tttaggcgac atattcgtcc tttgctccca tgaactggac aaaggagttc
    15661 tggtggaatt gaaaggtcgt gggtgcagac aatttgaaag ctatcttctg gcacaacaaa
    15721 gaagctggta tgagttcttt atggacgttt tggtggctgg cggtgtgatg aaacgccttg
    15781 accttgccat taacgataag acagggattt taaatatccc tgtactcact gaaaagtgcc
    15841 aacaggaaga atgtatctcc gtcttccgca gttttaaaag ctatcgcagt ggcgaactgg
    15901 tacgcaaaga ggaaaaggaa tgtatgggaa acaccctcta tatcggttca ttacaaagtg
    15961 aagtttattt ctgtatctat gaaaaggact acgagcagta caagaaaaat gatattccca
    16021 ttgaagacgc agaagtaaaa aaccgttttg agattcgatt gaaaaatgag cgtgcctatt
    16081 atgcagtccg tgatttactc gtctatgaca atccagagca taccgccttt aaaattatca
    16141 atcggtatat ccgttttgta gataaagacg attccaaacc tcgttctgat tggaaactga
    16201 atgaagaatg ggcttggttt attgggaaca atcgtgaacg attaaaacta accacaaaac
    16261 cagagcctta ctccttccaa aggacgctga actggctatc tcatcaagtt gccccgacct
    16321 taaaggttgc gattaaactt gatgaaatca accagacgca ggttgtaaaa gacattctcg
    16381 accatgcgaa actgacagac cgacacaagc agattttgaa gcaacagtca gtaaaagaac
    16441 aggacgtgat aacaacaaaa aaataactca aatacaaatt cattgaatat agagaggaga
    16501 acatttttat gaattttgga caaaacct
//
LOCUS       DAEPUT010000090        16220 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.092, whole genome shotgun sequence.
ACCESSION   DAEPUT010000090 DAEPUT010000000
VERSION     DAEPUT010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16220
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.092"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..237
                     /gene="tuf"
                     /locus_tag="KRL22_003150"
     CDS             <1..237
                     /gene="tuf"
                     /locus_tag="KRL22_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452162.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH1273595.1"
                     /translation="GGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTME
                     VDLINSIVVEEGLRFSIREGGRTVASGVVATIIE"
     gene            487..636
                     /gene="rpmG"
                     /locus_tag="KRL22_003151"
     CDS             487..636
                     /gene="rpmG"
                     /locus_tag="KRL22_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBH1273596.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            662..883
                     /gene="secE"
                     /locus_tag="KRL22_003152"
     CDS             662..883
                     /gene="secE"
                     /locus_tag="KRL22_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBH1273597.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            903..1445
                     /gene="nusG"
                     /locus_tag="KRL22_003153"
     CDS             903..1445
                     /gene="nusG"
                     /locus_tag="KRL22_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HBH1273598.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1484..1909
                     /gene="rplK"
                     /locus_tag="KRL22_003154"
     CDS             1484..1909
                     /gene="rplK"
                     /locus_tag="KRL22_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBH1273599.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1980..2678
                     /gene="rplA"
                     /locus_tag="KRL22_003155"
     CDS             1980..2678
                     /gene="rplA"
                     /locus_tag="KRL22_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBH1273600.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2730..2858
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2901..3407
                     /locus_tag="KRL22_003156"
     CDS             2901..3407
                     /locus_tag="KRL22_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBH1273601.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3465..3830
                     /gene="rplL"
                     /locus_tag="KRL22_003157"
     CDS             3465..3830
                     /gene="rplL"
                     /locus_tag="KRL22_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBH1273602.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            4222..5010
                     /locus_tag="KRL22_003158"
     CDS             4222..5010
                     /locus_tag="KRL22_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH1273603.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5481..9197
                     /gene="rpoB"
                     /locus_tag="KRL22_003159"
     CDS             5481..9197
                     /gene="rpoB"
                     /locus_tag="KRL22_003159"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBH1273604.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9239..12724
                     /gene="rpoC"
                     /locus_tag="KRL22_003160"
     CDS             9239..12724
                     /gene="rpoC"
                     /locus_tag="KRL22_003160"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBH1273605.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            13013..13435
                     /gene="rpsL"
                     /locus_tag="KRL22_003161"
     CDS             13013..13435
                     /gene="rpsL"
                     /locus_tag="KRL22_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBH1273606.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13561..14031
                     /gene="rpsG"
                     /locus_tag="KRL22_003162"
     CDS             13561..14031
                     /gene="rpsG"
                     /locus_tag="KRL22_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBH1273607.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            14080..16146
                     /gene="fusA"
                     /locus_tag="KRL22_003163"
     CDS             14080..16146
                     /gene="fusA"
                     /locus_tag="KRL22_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH1273608.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6348 a         2020 c         3308 g         4544 t
ORIGIN      
        1 ggtggaagac atacaccatt ctttgatgga tatagaccac aattctattt cagaacaaca
       61 gacgtaacag gagcttgtaa gttaccagaa ggaatagaga tggtaatgcc tggagataac
      121 gtaacaatgg aagtagactt aataaactca atagttgtag aagagggatt aagattctca
      181 ataagagaag gtggaagaac agtagcttca ggagttgttg ctacaataat agagtaattc
      241 tttactaaac tgatggatta aaaggaataa caaaaagagg ggttatgctc ctcttttttt
      301 aacatagaaa tacaaaaaca ttgacacagc ataggatttt gtgataactt atacaaggta
      361 atgattatag gaagttaata atatcttgaa tactgtagat ttttaataaa tacatatttt
      421 aaagatatta tattcacata tattaacaat atatattatt gtattacaaa gttggaggtg
      481 tatcagatga gagttaaagt aactttagca tgtacagagt gtaagcaaag aaactacaac
      541 actactaaga ataagaaaaa caatccagac agaatagaat tacaaaaata ttgtagattc
      601 tgtaaaaagc atacaactca taaagaaaca aaatagtttt ttataaggat gtgagtatgg
      661 aatggctgcc caaaaaaatg acggtgcaaa aactaaaaaa aggtttagtt tgtttggata
      721 cttaaaagaa actaaacaag aattaaaaag agttacatgg ccgacaaaaa aggaactgtt
      781 taaaaacaca agtatagttt taactgtagt tatttcatgc actatattag tatggggtat
      841 agacactata ttatctggtg cactagcgtt attactaaaa tagacgaaaa gaggtaagtt
      901 aaatgtcaga attacaagaa gcaagttggt atgtagttca tacctattcg ggacatgaaa
      961 ataaagttaa agctacaatt gagaaagcag ttaaaacaag aggtatggaa gactgcataa
     1021 gacaagtagt tgttccaaca gaagaagtag tggaaactac taaaactgga aaagaaaaaa
     1081 ctagacaacg taaagtttat ccaagttatg ttttggttaa aatgataata actgatgaat
     1141 cttggtatgt agtaagaaat actaagggag ttacaggttt cgttggacct ggttcaaaac
     1201 cagtgccatt aagtgaagac gaagtcaaag ctatggggat agacacaaca gaccctaaag
     1261 tagtaaatag cgatattgat tttgaaatag gagatacagt aaaagtatct caaggaccat
     1321 ttagtggaca aataggtaac atagaagaaa ttgacttaga aaatagagaa gtcaaagtat
     1381 gcataaatgc atttggtaaa aggactctat ttgtaataga gcttgaaggt atagaaaaaa
     1441 tctaatacta tattatagaa aaatctgagg aggtgcgctc aaaatggcta aaaaagttat
     1501 aggtcaaata aaattacaaa tacctgcagg aaaggctact ccagcgccac cagttggacc
     1561 agcattagga caacatggtg ttaatataat gggattcaca aaagaattta atgctaaaac
     1621 tgcagatcaa gctggaatga taataccagt tgttataact gtatatcaag atagatcatt
     1681 cagttttata acaaaaactc caccagctgc agttttaatt aaaaaagcat taaacttaaa
     1741 atcaggttct ggagaaccaa acaagaaaaa agttgctaaa atgacttcag ctcaagtaag
     1801 agaaatagct gaattaaaga tgcctgactt aaatgctgca tcagtagaag ctgctatgag
     1861 tatgatagct ggtactgcta gaagcatggg tgttgtaatc gaagactaat taaaagatac
     1921 actttttttt ataaagtggg aggctagaag ccgaaattaa ccacgaggag gaaaataaaa
     1981 tggctaaaaa aggtaaaaga tatgcaggtg cattacaaaa agtagataga actaaatttt
     2041 atgatgcatc agaagcatta acattagttt cagatatagc tggagctaaa tttgatgaga
     2101 cagtagaagc acacattaaa ttaggtgttg actcaagaca tgctgaccaa caagtaagag
     2161 gtgcagttgt attacctcat ggaactggta aaacaaaaag agttttagtt tttgctaaag
     2221 gtgaaaaagc taaagaagct gaacaagctg gtgctgactt tgtaggagct gaagaattag
     2281 ttcaaaaaat acaaggtgaa aactggtttg actttgatat agtagttgct actccagata
     2341 tgatgggtgt agtaggtaga ttaggtagag tattaggacc taaaggttta atgccaaacc
     2401 ctaaatcagg aacagttaca tttgatgtag ctaaagctat agatgaaata aaagctggta
     2461 aagttgaata cagattagac aaaactaaca taatacacgt tccagtagga aaagtatcat
     2521 ttggtggaga aaaattaact gaaaacttta ctgcattaat ggatgctata ataaaagcta
     2581 aaccagctgc tgctaaagga caatatttaa gaagtataac agtagcttct tcaatgggac
     2641 ctggagttaa aataaaccca gcaagaacag ctgaataata aaactgttga cacaggttga
     2701 caaaaatgtt attatatcac ttgtcaatgt aaaaaagaat agatttgccg tagatagtgg
     2761 gtgcgagagc ttaatatccc gccgaggttt tagataaatt gagattacta aagcttttga
     2821 tgtctacttt tggcaacaaa agctttttat aatgttgcgg taaatactaa gcctatttgg
     2881 tgaaggaggt gcacatctat atgagaaaag ctatagaaat taaatcagaa gttgtttctg
     2941 agatagttga aaagttacaa aaatcttctg ctgctgttgt tgtagattac aaaggattaa
     3001 cagttgaaga agtaactgag ttaagaaaac aaatgagaga agctggtgta gattacaaag
     3061 tatacaaaaa tactttagtt agaagagcag ctaaagaagt tggtatagag caatttaatg
     3121 atgaattatt agttggaact aatgccatag catttggata tgatgatcca gttgctccag
     3181 ctagaatatt aaaaggattc atggattctc atccaaaaat gaaattaaag atgggtattg
     3241 tggaaggtgc attctatgat gaatctaaga ttgttgaaat ggctaacata ccatcaagag
     3301 aagttcttat cgctaaatta cttggtagct taaaagctcc agtatcaaac ttcgcatact
     3361 taatagatgc aatagcgaaa aaggcagaag gtcaagaaga agcttaattg cttaactaaa
     3421 aaattataaa tattaatttg aaataaaatt cggaggtgct aaaaatgaca atagaacaaa
     3481 tattagaagc tatagaaaat atgaaagttt tagaattaaa tgaattagtt aaagctgctg
     3541 aagaaaaatt cggtgtatca gcttcagctc cagtaatggt agctggtgca gctgctggtg
     3601 gaccagctgc tgaagaaaaa actgagtttg atgtagtatt aactgacgtt ggttcttcaa
     3661 aagttggagt tataaaagca gttagagaaa taacaggatt aggattaaaa gaagctaaag
     3721 aagtagttga caatgctcct aagacagtta aagaaggagc ttctaaagaa gaagctgatc
     3781 aaataaaaga gaaattagaa gctgctggag ctaaagtaga agttaagtag tttctttaaa
     3841 aagataccca ttgggtatct ttttttattt ataaaaaact ataaagaaag tatttggaat
     3901 tataaagaaa gtatttttat aaaataaaaa aaatttatat aatagtacta aattaagggt
     3961 atcatatatg gtgtaatggt attttaattt aacattatta tcaaattaaa atataaacaa
     4021 ttgttgtaat gtctgtatat aaagtatata attaaactaa aatgtaaaat tttacatttt
     4081 agtttaaaaa aatacacgag tgttttataa ataaaatgta ataaataatt aattaacaaa
     4141 tataaatttt aaaataagtt agatatttag aaaaatcgaa atttgtagga tttaaaggac
     4201 atattcaagg aggagttaat aatggaaaaa ttacaaggaa aaattgcagt agttactgca
     4261 gcaacaaaag gtattggatt agcatcagca gagatattag caaaaaatgg agcaactgtg
     4321 tacttagcag ctcgttcaga agaattagct aatgaagtta taaataaaat aagtgcagaa
     4381 ggtggttgtg ctaagtttgt ttactttaat gctcgtgagg aagagacctt tacctcaatg
     4441 atagaagagg tagttaaaaa agaaggtaag atagatatac ttgtaaacaa ttttggttca
     4501 acaaaccctt ctcttgacaa agaccttgta actggagata cagataattt ctttgacaca
     4561 gtaaatacta atttaaaaag tgtgtattta ccatgtaaag cagcaattcc tcatatgata
     4621 aagaatggaa aaggaagtat agtaaatata tcaagtatag gttcagtatt acctgattta
     4681 tctagaatag cttactgtgt atcaaaagca gcaatcaact cattaactca aaacatagct
     4741 acacaatatg ctaaagacaa tgttagatgt aatgctgtac ttccagggct tattgcaact
     4801 aaagcagcat tagacaatat gtctccagag ttcataaaag aatttttaaa gcatgttcct
     4861 ttaaatcgta taggggaacc agatgatata gcaaaagctg ttctattcta tgctagtgat
     4921 gactcatcat ttataacagg ggatttactt gaagttgcag gaggatttgg tttacctact
     4981 ccacaatttg cagataatat attaggataa ttaaattact aatatgcaat gaaagcttat
     5041 gcattagtta tagtagaaat gatattttta taaaggccat agatataatt tatattggaa
     5101 aggtttgagg ttcaaaattc caagttaaat ttatttatgg tctttatttt gtatatttta
     5161 ataaattgta tatatttgta taaatgtaat tatttacaat cattttaata tggaattata
     5221 attaaatagg ggggatggta cttgtataaa attttttata gaaaattaga cctataaatg
     5281 aaaaatatgg attttatatt ggaaaattgt acataataca taatatatgc ttaaaataat
     5341 ttacaaaaaa tcaaaaataa tgcatagttt acatataaga taaaaaatat attgaaaaat
     5401 acttgacatt atgctaaaat tattagatgc gttagaatga actattgttt tatttttaat
     5461 tattgagagg tgaaaagtga atgccacatc ctgtcacgat aggtaaaaga actagaatga
     5521 gcttttctaa aattaaggaa atagctgatg tgccaaatct tatagaaatt caagtagatt
     5581 cctatgagtg gtttttaaaa gaaggtttaa aagaagtgtt tgatgatatt tcaccaatag
     5641 aagattatac tggtaatctt atattggaat ttgtcgacta ttctctagat gataaaccaa
     5701 agtacgatat agaagagtgt aaagagagag atgctacata ttgtgcacct ctaaaggtta
     5761 aggtaagact tataaataaa gaaacaggtg agataaaaga acaagaagtg tttatgggtg
     5821 acttcccttt aatgacagaa agaggaactt tcgttataaa tggagcagaa agagttatag
     5881 taagtcaatt agttagatct cctggtgttt actatgcgga agaaagagat aaaacaggta
     5941 agagattgat ttcatctact gtaattccta atagaggagc atggttagaa tatgaaacag
     6001 attctaatga tgtaatatct gtaagagttg atagaacaag aaaacaacca gttacagttt
     6061 tacttagagc tttaggaata ggaacagatg cagagataat tgacctttta ggagaagatg
     6121 agagattatc tgctacatta gaaaaagata atactaagac agtagaagaa ggtcttgtag
     6181 agatatacaa aaaattaaga ccaggtgaac ctcctactgt agaaagtgca tcatctttat
     6241 taaatgcttt attctttgac ccaaaaagat atgacctagc aaaagttggt agatataaat
     6301 tcaataagaa acttgcttta tgttatagaa taatgaataa aatttcagca gaagacataa
     6361 taaatccaga aactggagaa gtatttgtaa aagctggaga aaaaataagc tatgatttgg
     6421 ctaaagccat acaaaatgca ggtataaatg tagtaaatct actaatggat gatgataaaa
     6481 aagttagagt tataggaaat aattttgtgg atattaagtc tcacattgat tttgacatag
     6541 atgatttaaa cataaaagaa aaagtacatt atccaacttt aaaagaaatt ttagatggat
     6601 atagtgatga agaagaaata aaagaggcta taaaatcaag aattaaagaa cttataccaa
     6661 aacatatatt attagatgat ataatagctt caataagtta tgagttcaat atattctata
     6721 atataggaaa tattgatgat atagatcacc taggaaacag aagaataaga tctgtaggtg
     6781 aattgttaca aaatcaagtt agaattggtc tttcaagaat ggaaagagtt ataaaagaaa
     6841 gaatgacggt tcaagatatg gaagctataa cgcctcaagc gttagttaac ataagaccag
     6901 tttcagctgc aataaaagaa ttttttggta gttctcagtt atctcagttc atggatcaaa
     6961 caaatcctct atctgagtta acgcataaga gaagattatc agcccttggg cctggaggtc
     7021 tttcaagaga aagagctgga ttcgaagtgc gtgacgttca ccattcacac tatggtagaa
     7081 tgtgtccaat agagactcca gagggaccaa atatcggtct tataaactct ctaggaactt
     7141 atgcaaaaat aaatgaattt ggatttatag aatcaccata tagaaaattt gataaagaaa
     7201 catcaacagt tactgatgaa atacattatt taactgctga cgaagaagat ttattcgtaa
     7261 gagctcaggc aaatgagcca ttaacagaag atggtaaatt cgtaaaccat agagttgttt
     7321 gtagaactgt aaatggtgct gttgaaatgg ttcctgaaag tagagtagat tacatggata
     7381 tatctcctaa gcaggttgta tctgttgcca ctgctatgat acctttctta gaaaatgatg
     7441 atgccaaccg tgcccttatg ggagcgaaca tgcagcgtca ggcagtgcct ctagttagaa
     7501 gagaagcacc aattatagga actggtatag aatacagagc agcaaaagac tctggagcag
     7561 ttgttgttgc tagaaattct ggtatagcag aaagagtaac agcagatgaa ataattataa
     7621 aaagagaaga tggaaacaga gatagatata atctacttaa gtttaaacgt tcaaactcag
     7681 gtacttgtat aaatcaaaca cctataataa ataagggtga ccagataata aaaggtgatg
     7741 ttatagcaga tggtccagca actgatttag gagaagttgc acttggaaga aactgtctta
     7801 tagcattcat gacttgggaa ggttataact acgaggatgc tatattaata aatgaaagat
     7861 tagttaaaga agatagatta tcaacaattc atatagaaga atatgaatgt gaagctagag
     7921 atacaaaact agggccagag gaaataacta gagatatacc taatgttgga gatagtgcaa
     7981 ttaagaactt agatgacaga ggtataataa gaataggtgc agaagtagac tcaggtgata
     8041 tattagttgg taaagtaact ccaaaaggag aaactgaact tactgctgag gaaagattac
     8101 ttcgtgcaat atttggagaa aaggctagag aagttagaga tacttcactt aaagtgcctc
     8161 atggtgaatc tggtataata gttgatgtaa aagtatttac tagagaaaat ggagatgatt
     8221 tatctccagg agtaaatgaa ttagtaagat gctatatagc taaaaagaga aaaataaaag
     8281 ttggagataa aatggctggt cgtcatggta ataaaggggt tatctcaaga gtattacctg
     8341 aagaagatat gccattcatg gaaaatggaa caccactaga cataatactt aacccacaag
     8401 gtataccatc acgtatgaac attggtcagg ttttagaagt tcatttagga cttgctgcta
     8461 agacattagg atggtatgta gcaacatcag tattcgatgg tgctaatgag tatgacataa
     8521 tggatgctct tgaagaagct gggtatccta gagatggtaa attaacttta tatgatggta
     8581 gaacaggtga gtcttttgac aacagaataa ctgttggata tatgtactac ttgaaactac
     8641 atcacttagt agatgaaaaa ctacatgcaa gaagtactgg accatactca ttagttactc
     8701 aacagccact aggtggtaaa gcacaatttg gtggacaaag atttggagag atggaggttt
     8761 gggctctgga agcatatgga gctgctcaca tacttcaaga aatacttact gttaagtctg
     8821 atgacgttgt aggtcgtgtt agaacatatg aagctatagt taaaggtgaa aatatacctg
     8881 aaccaggaat cccagaatca tttaaggttc ttataaaaga acttcaaagt ttatgcttag
     8941 atgtaaaagt attgacagat gaagaccaag aaatagaagt aagagaatct gtggatgaag
     9001 atgatacaat aggtgaattt gagctagatg ttgtaaatca tatgggagaa gttgaagaaa
     9061 gtaatataat agaagaaatt gaagatgatt ttgcagaaaa tgcagaagat gaggatatag
     9121 agaatttaga agaattcact gaagatgatt tatttgaaga agaaatagat tttgatagtg
     9181 atgactttga tatgtaaatt taattaatgt aaatctcaaa tagaagggag agaactcctt
     9241 gtttgaatta aacaatttcg agtcgataaa aatagcattg gcttctccag aaaaaataag
     9301 acaatggtct aggggagaag ttaaaaagcc agaaactata aattaccgta ctttaaaacc
     9361 agaaaaagat ggtcttttct gtgaaagaat atttggacca caaaaagact gggagtgcca
     9421 ctgtggtaaa tatagaagag ttagatataa aggtgtagtt tgtgatagat gtggagtaga
     9481 agtaactaaa tcaaaagtaa gaagagagag aatgggacat atagagctag ctgctcctat
     9541 gtctcacatc tggtacttca aaggtatacc aagtagaatg ggacttttac ttgatatgtc
     9601 accaagatcg ttagaaaaaa tattatactt tgcctcatat gtggtagttg atccaggaga
     9661 gactggatta aacgaaaaac aattgcttac agaaaaagaa tacagaactg ctcttgaaaa
     9721 gtatggatat acttttactg taggaatggg tgctgaagct gtaaagacat tactacaaaa
     9781 tatagattta gagcaacaaa gtaaagacct aagagcggag ttaaaagata gtacagggca
     9841 aaagaaagtt agaacaataa gaagattaga agttgtagag gcatttaaaa agtctggaaa
     9901 taaaccagaa tggatgattt tagatgcaat accagtaata ccaccagatt taagaccaat
     9961 ggtacaactt gatggtggaa gatttgcgac ttcagaccta aatgatttat atagaagagt
    10021 tataaataga aacaatagac ttaaaagatt attagagctt ggagctccag atataattgt
    10081 aagaaatgaa aaaagaatgc ttcaagaagc tgttgatgca ttgatagata atggtagaag
    10141 aggtagacct gtaacaggac ctggaaatag accacttaaa tctttatcag atatgttaaa
    10201 aggtaagcaa ggtcgtttcc gtcaaaactt acttggtaag cgtgttgact actcaggacg
    10261 ttctgttata gttgttggac cagaacttaa attttatcaa tgtggacttc caaagaagat
    10321 ggcattagaa ttattcaagc catttgttat ggataaatta gttaaagaag gttatgcaca
    10381 taatataaaa agtgcgaaat ctatagtaga aaaagttaag ccagaagttt gggatgtttt
    10441 agaagatgtt ataaaaagtc atccagttct tcttaaccgt gcaccgactc tacatagatt
    10501 aggtatacaa gcatttgaac caatcttagt tgaaggtaag gctataaaac tacatcctct
    10561 tgtatgtaca gcttataatg cagactttga tggtgaccaa atggcagttc atgtaccttt
    10621 atcagtagaa gcacaagcag aagcaagatt cttaatgctt tctgtaaata atatacttgc
    10681 tcctaaagat ggttcaccta taactactcc atctcaggat atggttttag gttgctatta
    10741 tctaacaata gaagcccaag atggagctaa aggaacaggt atggtattta aagactttaa
    10801 tgaactatta cttgcttatt acaataaatc agttcatcta catgcattag tgaaacttaa
    10861 ggtaacactt gaagatggaa gaagttcatt ggttgaaagt actgttggta gatttatatt
    10921 taatgaaaat atacctcaag acttaggttt tgtagataga aaagaaaatc catttgcact
    10981 tgaagttgat ttcttagcag ataaaaaatc tcttggtaaa ataatagata aatgctttag
    11041 aaaacacgga aatacagaaa cagctgaatt actagattat ataaaagctc taggatttaa
    11101 atattctaca ttaggtggca taacagttgc tgttgatgat atgagtgtcc cagaagaaaa
    11161 gaaagtattt atagctgagg cagaagctaa agttgataag tatgaaaaag catacagaag
    11221 aggtctaatc tctgatgaag aaagatatga aaaagttata gagacatgga cagaaacaac
    11281 tgataaagtt actgatgctc ttatgggtgg actagataga ttaaataata tatatataat
    11341 ggcacattca ggagccagag gttctaaaaa ccaaattaga cagctggcag gtatgcgtgg
    11401 tcttatggca aatgcatctg gtaaaacagt tgagatacca gttaaatcta atttccgtga
    11461 aggtttatca gtactagaat actttacatc ttcacatggt gccagaaaag gtcttgccga
    11521 tacagctata cgtacagctg aatctggata tttaacaaga agacttgttg atgtaagtca
    11581 agatgttatt gtaagggaaa tagattgtgg aacagaagat actacagaga tttatgctat
    11641 aaaagaagga aatgaagtta tagaagagat atatgataga attgtaggaa gatatactat
    11701 agaccctata ttaaatcctg aaactggaga agttatagtt gaggctgatt caatgataca
    11761 agaagatgaa gcagaaacta tagtagcttt aggaattgaa aaaattagga taagaacagt
    11821 tcttaactgt aaaactaatc atggagtttg ttctaagtgt tatggtagaa acttggcaac
    11881 aggaaaagaa gttaatatag gtgaagcagt tggtataata gcagctcaat ctatcggtga
    11941 gccgggtact cagcttacaa tgcgtacatt ccatactgga ggagttgcag gagctgatat
    12001 aactcaaggt ctaccaaggg ttgaagaatt atttgaagct agaaaaccaa aaggattagc
    12061 tgtaataact gaagtatctg gtagagttga aattgatgaa acaggaaaga gaaaagaagt
    12121 aaatgtaata ccagaagaag gcgagactca aacatatgta attccatatg gttctagatt
    12181 aaaagttaag caaggtcaaa tgctagaggc tggagaccct ctaacacaag gatttataaa
    12241 tcctcatgat atagtaagag taaatggtgt taagggagtt caagaatata tagttaaaga
    12301 agttcaaaga gtgtatagac ttcaaggggt tgatgttaat gataagcata tagaagttat
    12361 agtaagacaa atgctatcta aagtaaaagt tgaagaccca ggagatacag atttattgcc
    12421 aggtggatat gaagatgtat taacattcaa tgaatgtaat aaagatgcta tagataaagg
    12481 tctaagacca gcagttgcta aaagagtttt acttggtata actaaagcat ctcttgcaac
    12541 tgattcattc ttatcagcag cttctttcca agaaacaaca agagtattaa cagaggcagc
    12601 aataaaaggt aaagaagacc acttaatagg acttaaagaa aatgttatat taggtaagtt
    12661 aataccagca ggaacaggaa tgaagaaata tagaaatata gctgttgaaa aaattgaaga
    12721 ttaatagcat atagagtaaa gaaatcttga caaccattat ttgtggtgtt aaaatagtaa
    12781 agtgtgttgt ttaaaagtac actaagggct tgaacaagtt cttagtgact tttagatggc
    12841 aataaatgag aactaaaaag catcaagcta gaaaagtgct aatatcacat atttatgtgt
    12901 tatagacatt aaattgtaag taacgaatgt tacaatcagt cagtatgaat attcatattg
    12961 atgtagttgg cggtcactga taagatcgaa aatttggaag gaggtgcaga tgatgccaac
    13021 aattaaccaa ttagttcgta aaagtagaaa agcgctagag aagaaatcta ctgctccagc
    13081 attacaaaaa ggttacaact ctttaaataa gaaagtaact gacgctagtg ccccacaaaa
    13141 aagaggggtt tgtacttcag taaaaacagt tactcctaag aagcctaact cagctttaag
    13201 aaaagttgcc agagttagat taactaatgg tatagaagtt tctgcttata taccaggaga
    13261 aggacacaac ttacaagagc atagtgttgt tcttataaga ggaggaagag taaaagacct
    13321 tccaggggtt agataccata tactaagagg tactctagat acagcaggtg ttgataagag
    13381 aagacaatca agatctaaat acggtgcgaa gagacctaaa gaagctaaaa agtaaaaaca
    13441 attaatgatt gattatagtt cggtgcttta aatatatata tatatttacg gcatcacggc
    13501 attaaatgat ttatgtcgag tacctatgat ttaagttaaa taattaagga gggaagcgaa
    13561 atgccaagaa aaggtaatat tccaaaaaga gaagttttac cagatcctat gtatgggagt
    13621 aaggtagtta ctaaattaat aaataatcta atggtagacg gaaaaaaagg aaagtctcaa
    13681 agaatagttt atgatgcttt cgcaattgtt gctgaaaaga caggagaaga agctttagaa
    13741 gtatttaata aagcaatgga taatataatg cctgttttag aagtaaaagc aagaagagtt
    13801 ggtggggcaa actaccaagt gccaatcgaa gttagacctg aaagaagaca aacattaggt
    13861 ttaagatggc tagtaaaata tactagagct cgtggagaaa aaggaatggt tgaaaagcta
    13921 gctaaagaga taatggacgc agctaacaac actggagctt cagttaagaa aaaagaagat
    13981 actcataaaa tggcagaagc taataaagca tttgctcatt acagatggta ggatatatag
    14041 atatcttata aaattgagga tatcataagg aggataacca tggctagaaa gtttcctttg
    14101 gaaagaacta ggaatatagg aatcatggct catatagatg caggaaaaac tactactaca
    14161 gaaagaatcc tgttttatac tgggcaaact cataaaatag gagaaactca tgaaggagct
    14221 tctcaaatgg actggatgga gcaagaaaag gaaagaggta taacaataac ttctgccgct
    14281 actactgctt catggaaaga ccatagaata aacataatag atactcctgg acacgtggac
    14341 ttcacagttg aggttgaaag atctctaaga gttcttgacg gttcagttgc tgtattctgt
    14401 gcaaaaggtg gggttgagcc tcaatcagaa aatgtatgga gacaagctga aacttatgga
    14461 gtacctagaa tagcttttgt aaataaaatg gatatattag gtgcagattt ctacaatgtt
    14521 gtaagcatga tgaaatctag attaaattct aatgcagttc ctatgcaatt accaataggt
    14581 aaagaagatt catttatagg tataatagac ttattaaaaa tggatgctgt tatatacaaa
    14641 gacgacctag gggttgaaat ggaagaaaca gatataccag aagatatgaa agaattagct
    14701 gctgagtgga gagaaaaatt agttgaatca gtagctgaaa ctgatgaaga attaatgatg
    14761 aaataccttg aaggtgaaga acttactata gatgaattaa aagttgctat aagaaaagct
    14821 actatagctt gtgaaatgaa cccagttttc tgtggtacag cttatagaaa caaaggtgtt
    14881 cagttagtaa tagatgcagt tttagattac ttaccagcgc caactgatat accagctata
    14941 aaaggtatat tagcagatgg agaagaagct gaaagacatt cttctgatga agagccattc
    15001 tctgcattag cattcaaaat aatgactgac ccattcgttg gaaaactagc gttcttcaga
    15061 gtttattctg gaacattaga atcaggttct tatgttttaa atgcaactaa gaataagaga
    15121 gaaagaattg gtcgtatatt acaaatgcat gctaatacaa gagaagaaat aactaaagtg
    15181 tatgctggag atatagcagc agcagtagga ttaaaagata ctactactgg agacacatta
    15241 tgtgaccctg ctaatccaat aatacttgaa tctatggaat tccctgagcc agttatatct
    15301 gttgctatag aaccaagttc taaagcagct caagaaaaaa tgggtatagc tcttcaaaaa
    15361 ttagctgaag aagacccaac tttcacagtt aagactgacc aagaaacagg acaaactata
    15421 atatctggta tgggtgaatt acacttagag ataatagtag atagattatt aagagaattt
    15481 aaagtagaag ctaaagttgg tgcaccacaa gttgcatata gagagactat aactcaacca
    15541 gttgatgttg aatacaagta ctctaagcaa tcaggtggta gaggacaata cggtcacgtt
    15601 aagattagag ttgctcctca agagccaggt gaaggataca aattcacaaa caaaactgtt
    15661 ggtggatcag taccaaaaga atatgttggt ccagttgaca tgggtataca aggagctatg
    15721 caatctggta tagttgctgg atatccagtt gtagacgttg ctgttgagtt atatgatggt
    15781 tcttaccatg aggttgactc ttctgagatg gcgtttaaga tggctggttc aatggcattc
    15841 aaagatgcta tgaagaaagg taatgcagtt cttttagagc cttacttcaa agtagaagtt
    15901 gttactccag aagattacat gggagatgtt atgggtgact taaactcaag aagaggatta
    15961 atccaaggta tggaagctag aagtggtgca caagttataa atgcattcgt tccactttca
    16021 gaaatgtttg gatactcaac agacctaaga tcttcaactc aaggtcgtgc aacttacaca
    16081 atgatattcg atcactatga gcaagttcca gcttcagttg ctaagaaaat agctgaagga
    16141 aaataattta aaaataatta ataatataaa tataaaaaat aatcagctag atgagagata
    16201 tctctcatct agcacaagat
//
LOCUS       DAEPUT010000091        15901 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.093, whole genome shotgun sequence.
ACCESSION   DAEPUT010000091 DAEPUT010000000
VERSION     DAEPUT010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15901
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.093"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            51..647
                     /locus_tag="KRL22_003164"
     CDS             51..647
                     /locus_tag="KRL22_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HBH1273609.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(745..1704)
                     /locus_tag="KRL22_003165"
     CDS             complement(745..1704)
                     /locus_tag="KRL22_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1273610.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(1738..2469)
                     /locus_tag="KRL22_003166"
     CDS             complement(1738..2469)
                     /locus_tag="KRL22_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273611.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(2462..3232)
                     /locus_tag="KRL22_003167"
     CDS             complement(2462..3232)
                     /locus_tag="KRL22_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273612.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(3317..4027)
                     /locus_tag="KRL22_003168"
     CDS             complement(3317..4027)
                     /locus_tag="KRL22_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH1273613.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(4207..4359)
                     /locus_tag="KRL22_003169"
     CDS             complement(4207..4359)
                     /locus_tag="KRL22_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBH1273614.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(4385..6541)
                     /gene="feoB"
                     /locus_tag="KRL22_003170"
     CDS             complement(4385..6541)
                     /gene="feoB"
                     /locus_tag="KRL22_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH1273615.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(6641..6862)
                     /locus_tag="KRL22_003171"
     CDS             complement(6641..6862)
                     /locus_tag="KRL22_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1273616.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(6875..7087)
                     /locus_tag="KRL22_003172"
     CDS             complement(6875..7087)
                     /locus_tag="KRL22_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1273617.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(7408..10305)
                     /locus_tag="KRL22_003173"
     CDS             complement(7408..10305)
                     /locus_tag="KRL22_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1273618.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNTAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKDKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEEFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(10632..11240)
                     /locus_tag="KRL22_003174"
     CDS             complement(10632..11240)
                     /locus_tag="KRL22_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBH1273619.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISCQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKCLA"
     gene            complement(11500..12045)
                     /locus_tag="KRL22_003175"
     CDS             complement(11500..12045)
                     /locus_tag="KRL22_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH1273620.1"
                     /translation="MKKFVCTVCGYIHEGDTAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(12163..13986)
                     /locus_tag="KRL22_003176"
     CDS             complement(12163..13986)
                     /locus_tag="KRL22_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273621.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTILSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(13999..15774)
                     /locus_tag="KRL22_003177"
     CDS             complement(13999..15774)
                     /locus_tag="KRL22_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273622.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRKRIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         5284 a         2833 c         1562 g         6222 t
ORIGIN      
        1 tataatctaa ttacttgata ttaattttca tttgaaggag gttatctttt atgtcttgtt
       61 gtaattcaca attttgttgt aaaaataaaa ttgaatcatc atatataaaa tggcttttag
      121 aagttttagg tccagtcttt ttaggctcta aacctgctga aataataaat atttcgttta
      181 ctgatgtaaa tagagaggaa aaaattaatg atatttataa atatctatat aaatgtaaga
      241 aaatagattt tatagttatt gataaagaaa aaaagggatt aaaaatctta tttgtaaata
      301 aaaaagcatt atcagaaaaa ttaaaatgta aaaaaacagt aaacttttta aagtttttag
      361 gatacaaaca aaatacgaat gttaatgctt atttagagca tttagtagat aaacttaaga
      421 gtgatgtttt tcctgatgaa ataggtattt ttttaggata tcctcttaaa gatgtgattg
      481 gatttatggg atatagtaat tatgaagttt ctatgattaa atattggaaa gtttatggtg
      541 acacaaaaca atccgaggac acatattcga agtttttact tcaccgtaag aaaatgagaa
      601 aattactaga ctacataagt gtagataaaa tagtaagctg tttttaattg tatttttgta
      661 taataataaa aatacaccct cttttaccat atagtttcca taataaataa gggtgtattt
      721 tccactttaa tattttaaag tattctaatt ttgattgtac aacatatctt taatatttat
      781 tttcttttgt tgcattccat tagacattaa aaattcctgt gtatcttcta attcttttat
      841 atccttgtcc gttattttag aactaaagtc ataccaagaa tacatttctt ttgtttcatc
      901 taaagataaa ccaacttctt tagatacaac atccatcact tcatccttgt tttcattcat
      961 atattttaaa gtttcttcat gaaccttcat aaatcttttt actaattcag gatatttttc
     1021 agcaaagtca tcacttacag cagtaactat tattccactt actaatcctt ctccatttac
     1081 aatcattttg gcacctgaat ttatcgtttt caatgccact ggacctgcaa gcattgctac
     1141 atcagcactt ttactttcta atgcagaagc agcactagga atatccatat ttacatattc
     1201 aacatcatct atagtatagc cttctttagc aagtgcagca atcaacagtt gatgaagtat
     1261 agtccctttt ggacctacaa tttttttacc ttttaagtct tttatagatt taatattatc
     1321 attattagtt ataagcatat atccttttgg tgaacggcta taaatattcg taattttaag
     1381 accaacacca tttgatgcag ctattattgc agacgttcct cctaatgcat gtaaaaagtc
     1441 tagctcacct gctgctaatg cttgagtttg ctctggtcct gttgtcaatt catggaaatt
     1501 gacttttata ttgtcctttt taaattcctt tccaaataaa tcatcctttt tttctaatat
     1561 actaggaaca ttaagtggtg attttacata agttaaattt atttccttag gtaaactagc
     1621 ctcttttttt gcaggttcat ctttcttatc atttgttgtt gaacatccta cagtcccaac
     1681 caacaccatt attaaagatg tcattactgc taaaatcttt ttgtttcttt taatcaatta
     1741 aaactccccc aattccctta atatttcttt tttcaagttt atataatagt ttttagttaa
     1801 atctctatta tattcatctt cgacactaaa ttgtttaatc cttttatttt tactaaaaac
     1861 aattattttc tttgctattt ccatagcttc ttcaatattg tgagttacaa atactacacc
     1921 ttttttagta tttttatgga tatttacaac ttctttttgc atttttcttc ttgtgaagta
     1981 atctagtgct gcaaatggtt cgtccatcag caaaatatcg ggattgaagg aaagtgctct
     2041 tgctatactt actctgtgag ccattcctcc tgataattca tttggatatg agtttttaaa
     2101 cttttcaagc ttcatcattt ttaaatactt gtctaaatca actttatttc tattatcttt
     2161 ttcagtatgt aaaagtatat tttcacttac attcagccat ggcataagtc tactttcttg
     2221 aaataccatt cctacttttg gagtacactt tttatcatta ttaaaaaaat atatgtttcc
     2281 actagtagca ttttcaagcc ctgctaaaat tctaagtagc gttgttttcc cacatccact
     2341 ttcacctaat ataacagtta tctcttcact agatatattt aaagatatat tatcaagaac
     2401 taaatgctct ttattatcaa ctaaatattt cttatatata ttctctagca aaaatccact
     2461 tctaaccatt taaatcaacc tgcttccctt tgctaaattt tgttattatc tttgaaaata
     2521 gataatctga aagtatacct aaaaatccaa taacaaaaat tcctaccaat acaacatcag
     2581 ttctagacat atcttttcca tcagaaatca aatatcctag tcctgaagaa gctgcaataa
     2641 gctctgctcc aattatagcc ctaaaactat acccaagccc taaactaagt ccaacaacaa
     2701 tatccagcat agaattaggg attattattt tataaaaaat tctcttttta gataaattaa
     2761 aagatttacc tacttctatt aatttattgt cacaattttt tatacctttc aatgtattta
     2821 aaaatattgg aaaaaaggat gccaaaataa taattataat tttagattct tcacctatac
     2881 caaaccataa aataagcatt ggcaccaaag ctagtggagg tgtacttcgc ataaattcaa
     2941 atagtggttt gaaatattca tacatttttt tatttactcc aaataaaact ccaagtggta
     3001 tagccatcaa tgaacttatt aaaaaaccta ttaatatcct tcttacactg gcataaacat
     3061 ttaagaaaat agaaccgtca tatatcattt ttataaaagt atctaagact atttcaggag
     3121 gaggcagaat atagctactc catataccca aaacacatac tatcttccat aaaattaaaa
     3181 ttattaaaaa aatataatat cctttaagcc ttttatgaat tttctcaaac atataaaact
     3241 ccttttaaca tatctatccc tgctaccctt tttatttttt aatatcttaa ataataatta
     3301 agctatatca taagatttaa tctatgccaa gtcttaatcc acctgaactc attctatcag
     3361 aaggtgtaga atctgttttt aagccagaca atctttcaga tggttgtata atgactattt
     3421 gtccaggttc aacaaattcc atatgataag attctcctga agtctgacca ataaaagtct
     3481 tccatgatag ttttgatact ttaggatatg gttctcttcc agtccaagct actaatgcat
     3541 ctgggtcaac acaacaaggt ccttcaagaa ttagaggatt accatctgtt attatagcaa
     3601 catcttgatt ttgacctgtt ttatttacta aatgtgtagt aaaaagacct ttttgagata
     3661 ttacccctga accaatcaat tttacactgt aatttaattg ttcagaaaat gccaataagt
     3721 tttcactctc aacataaatg gaatcacctg ggtcaattga tattacatct acatggtaag
     3781 cattttgagc taggtaaatt tcaccttcac cttcaaccac cattattggc atttgttctc
     3841 ctgtcaatga cctctgaaca tgacctaata atgctcttcc caatccaccg ccattacttg
     3901 gacctaacag caatttttca aaattaaaat ttcctttaaa ggctaccata gcaccttttt
     3961 ttgcaaaaaa tttaccactt ccccttgcta tacacataag ctcgtttgta acatcaaatt
     4021 taaacataat attcacttat attgcttaat ttagcaataa tccctcctaa tcatatattt
     4081 atatataatt atacagtaaa attacagcat agtctaacct acttcaaata tgaaatttgt
     4141 tatttatata aaaaataaga acctgataat aaagcaattt aactttttat caggctctta
     4201 tcctatttat ctcttagcgc tatgacaact cttactactt gagcatccag aacaaccaca
     4261 tccacaactg ctaccattct tttttgaatt tttaaccata tacattacag ctagtgccat
     4321 taatactact acaatagctg ctataataaa tgtagccata ttcatcactc cttatttata
     4381 tgaattaatt tttcatataa cttaatttac ccattttttc ttttttcata tttttatttg
     4441 aataagttaa aactacaaag actactgcta ctgctataaa tatagatatt attgccccag
     4501 caatacttcc tccagtacct aaaactaaac ttccaacttg atttataaga agagcaatta
     4561 tatacgctgt taaagtttgg aatcctaatg taatccatgt ccatttccat gaacccattt
     4621 ctctttttat ggctccaata gctgcaaaac aaggtgcaca aagcatatta aatgccataa
     4681 atgcaaacgc actagctact gtaaacatgc ttgcaactga agcaagaagt gttgggtctt
     4741 gctctgttgc atctgatata ccaaataaaa ctccaaatgt tccaactaca ttttccttag
     4801 ctactagacc tgtaactgtt gctactgatg attgccaatt tccaaatcca agaggagcaa
     4861 atattggtgc aactatattt cctaagctag ctaatatact atctccagca tctaccattt
     4921 gtaatgacca attaaatgat tgtaagaacc agattactcc acaagcaaca aatataattg
     4981 ttcctgcttt gattataaat gcttttcctc tatcccacat atgtattaaa acaccttttg
     5041 cacttggaat atgatattga ggtaattcca taacaaatgg agatggttct cctgcaaata
     5101 aactagtttt ctttaatata attccacaaa tgattatcat tgcaatacct aagaaataca
     5161 ttgatggagc tacccatgaa gcacctccaa ataatgcccc tgcaaataat gctattattg
     5221 gaatcttagc tccacatgga atgaatgtag ttaacataat agtcattttt ctatctctat
     5281 cattctctat agtacgagtt gacataactc ctggaactcc acaacctgaa cttataagca
     5341 ttggtataaa tgattttcct gaaagaccaa acttacggaa aattctatcc attataaaag
     5401 ctacacgtga catgtaccca caatcttcta atattgataa taataagaat aaaagcatga
     5461 tttgtggtac aaatcctagt actgctccaa ctccaccaat tagaccatca actacaagtc
     5521 cttgtaacca ctctgctaca tttaaagaag ctagaaaatt acttacattg ccttgaataa
     5581 tttctccaaa cagtacatca tttgtccaat cagttgctat agtacccaat gaacttactg
     5641 ctatatagta aactccccac attataagtg caaaaatagg taatgctagt atacgatttg
     5701 ttacaatctt atctatctta tctgatacag tttccttacc ttttcgattc ttctttatta
     5761 tacttgaaat tattgaacta ataaattcat aacgattggc tgttattata ctttcactat
     5821 catcatccaa ttcatcttca caatttctag ttatttcttc aatactattc aatattgttt
     5881 tagaaatatc aagtttttgt ataacatttt catctctctc aaatagcttt atagctaacc
     5941 agcgtgtttc tacatctata tatggagtct tttcttctat tattttttca attttttcta
     6001 ttgcatcctt actttcatca acaaagggta atttgaaatt taatttattg ttactacttg
     6061 caagttcaac tgccttttca gcagcctcca taattccttg acctttaact gctgttactt
     6121 ctaccactgg gcaacctata acttcagata gttctttaat atttatctta tcaccattct
     6181 tatttacaat atccatcata ttaagagcta taacggtcgg tatacctagc tctaaaactt
     6241 gagttgtaag atataaattt ctctctatat ttgatgcatc tacaatattt attactgcat
     6301 ccggcttatc atctagcata aaattacgtg taactacttc ttctaatgta tatggagata
     6361 aagaataaat acctggtaaa tctactattt ccacatcttt atttcctttt aattttccac
     6421 cttttttttc aactgttact cctggccagt taccaacata ttgtgatgag cctgtaagcc
     6481 cattgaacat tgttgtctta ccacagttag gatttcctat gagacctatt tttattgaca
     6541 tttccattcc ctccattatt atttaaatac atcactgttt gtgatataga aaatcattct
     6601 cattatataa ttacattaac cctactctaa ttaatcttta ttattccaca ataatttttt
     6661 ctgcatctga cttacgaatt gatagttcat aatctctgac tgttacctca attgggtcac
     6721 caagaggagc tacttttctt ataaatatat taacacctct tgtaatcccc atatccatta
     6781 tacgtcttcg tgtagctcct tctccttcta actttttgac ttttacagtc tctccacact
     6841 taatatcctt cagtctgttc atgtcattac ctccctatat tattattcta cttgccattt
     6901 ttttatctaa tgcaactcta gtatctttta cgtctattat taagttacca tctatcttag
     6961 aaactatttt aacatttgta cccactacaa aacctatact atttaaaaaa gtcctcgtct
     7021 tatcacttcc cgaaattttc tttataacta cttcttcacc tgtatttgat aatatcaatg
     7081 gcatcatata atatccctcc tcttaaagta atttaaatct acaagcaatc gttatcttat
     7141 atataaatta caatacctta aatcttaatc tattaaaata atatcctatt ttttccttct
     7201 ttttacaatt cctaattttg atttaagtct atcacaatag tatatttttt gcaagtgatt
     7261 attgtattct tttgattttt tttctcattt gatttatttt attaataaaa tcgtaaaaat
     7321 taatacaaaa ataaagatgc tctaaaatag tatactcaac taatattaaa gcacctttat
     7381 tatatatgtc attatttaca cattgcttta ttctttttta aaagcgattt tttcaaactc
     7441 ttttacaggc attggcttag aaaacaaata tccttgtacc atatcacacc caatttgctt
     7501 tagaaattct acttgcgaaa tagtctctac accttctgat attactttca ttttcagttc
     7561 ctttgccatt ttaatgacat tagatataac aattttttca ttattactct catctttttc
     7621 tgtaaaaaat gctctatcta gttttaatat gtcaacaggc aattctttta aaagattaag
     7681 agaggaatat cctgtaccaa aatcgtccat agagattaca aatccctttt ctttcaaatt
     7741 gttcattgta tcaagtaatc cttctatatt atctaatact gctgtttctg ttagctctaa
     7801 ttctataagt cttgtcggaa ttttgtattt atctacaatt aatttaaact cctctataaa
     7861 attactattt acaaaatgca ttcgagacaa gtttacagat ataggtacta ctttttgtcc
     7921 ttcatccatc cattctctaa tctttttaca cacttcctca aatacataga aatcaatatt
     7981 tacaataaaa ccattcctct caaatacagg aataaattct attggtggta ttagaccttt
     8041 ttgtggatta tcccaacgaa caagagcctc tgcccctata atttgataat ctgaaaggct
     8101 atatttaggt tgaaaataaa caataaattc tccattatta agagcatcta ccattgaatt
     8161 ttcaatttct ttctctttta atattttttt gtgcatttcc ttatcgtaaa aagcaaatga
     8221 atttttatga ccacctttta tagtttttct tgcagtatta gctctatcca taatagtatt
     8281 tatgtcatta tcacttttac ttattttata tataccacaa tctaaaatca atttataata
     8341 gtttatttta ggattactaa gtatttgaac cttattgtaa atattgttta accttgtttt
     8401 aatatcatca tctgtcttat acttaataag aagaacaaaa tggtcagcag aaactcttgc
     8461 aaaaatttca tcttccttta attcacttgc aatagtattt gatatatgta tcaaagtatc
     8521 atttcccata tcatatccaa acatatcatt tatatattta aatttgtcaa catctatata
     8581 aaacaacgca tattcttctg gattattttt agcaaacagt ttattagaat ttattttaaa
     8641 tttatctata ctatctgctc ctgtcaatgg gtctgtatat gctatcttcc ttagataatc
     8701 ctctttcttc tttttattat aaattatata tttaatagca attaagaata aaatacatac
     8761 aaaagaaata atttgtattg aatattcttt aaaaataaca ccaaatggta ctttataagg
     8821 tttgtcaata gtattagaat atatacaatc acttaattct tcttcagtaa ttttgtctat
     8881 tgatttattt aaaatagaca ctaatatagg gtcagtttta tttgataccc ctatacgcat
     8941 cccatagctt gtatctaaaa cagatataac agataaattc tcactctttc cttctcttaa
     9001 aagttcatca aactgataag aactaagtat cattaagttt gctttacctt catttatagc
     9061 atttagacaa ctttctacac tcttataaga tgttgtctta gcattttcaa aactcttttc
     9121 tatataagaa tcaatagact tataactact agttaaagca atatttaaat cattattgag
     9181 attggtatcc aattttccta ccataatcat tggaatattt atgtatggat ttgtcaattt
     9241 catattaaat cgttttgcct tatcattttc attgattgag ccacatagca tagttgcctt
     9301 accacttttt atgtaatcaa gactctcatt ataatttttt gttttaatat attcaaattt
     9361 tataccacat ttttttgata taattgacat taaatcggaa cttatacctt taaatgaatt
     9421 gctttcttta tcataatact ctacaggaga ccactctgaa tcatatacca tagtaagttt
     9481 tgggtttgct ttaataaaat tcatttcttg ccgagtaaat gctatggaat tgttgacctc
     9541 tcttttgaaa tattttttat ataattccaa ctcataatac atatcattta tttttaattc
     9601 ttttaaagca taatctaatt cttttaccaa attaggttta tcttttgcag tagcaaaata
     9661 aaaaggttct actgaaaatt tgctaactat tttcattcct ttagcattta taatacttcc
     9721 acaaacaaat gcatctgcct ttttttcatt gacggactca attaattcat caatagaatt
     9781 acagtatata tattcaactg aaaaattatt ttcttctcta tacttctcaa atgcagtatt
     9841 atgaaagttt cctctaagta cagctactct cattccctta aaggaactta tatcttcata
     9901 aaacatatta ttgttactat cctttgtata tagtgcacta tattcatatc ctgaacttag
     9961 tttaggaaaa ttaaatagtt tatttctttc atcattcttc tgtaaaggtc cgagtaagtc
    10021 tatttcaccc ttttctagtc tgtctaaaca ttcttcccaa gaccctttta caaattcata
    10081 ttcccatctt gtatattttg agatttctct tagataatca taaccatatc ctgtataaga
    10141 atgctctttt gatgaggata ttattccata gtcatcacaa tatccaactc ttattttttt
    10201 tgaattttca gactcatcag caaagcatag tatattgtta aaacatgata taataagtaa
    10261 aaatatcaaa gaaagtatca agaagtgctt tttaaatgct ttcatattta aaaacctcca
    10321 atttgccaac ttactttaac ttatttggtt ttctagttgt aactactttt attgtaatgg
    10381 taaatatatc aaattgcaat attctcatat aatattctta ttcaactata ataaatttat
    10441 tattatctat ttaaatacac tatctaatat tagtttctta taagtcataa aagcacaact
    10501 aacactataa ttctagtgat taattttatt tcaaaaaata taataacact actaatattt
    10561 taaatatcaa tagtgtcata aaaacttttc agattaatta aatctttcta tatattttat
    10621 aataatctaa atcatgctaa acatttagac agaaaacttt tttctttaat agtaaatact
    10681 tttgtttgaa tatcagaata attatttgaa tatctatcta taaaaccatg atttgcatct
    10741 aaaatctcaa tttggatatt ttgtttccta gaaagttggc aagaaataga atcaacatca
    10801 aatgaatcgt gctttgcaaa tactaataag gtaggacatt ttggaattac atccatgtaa
    10861 tctcgaatcc gagagccata acaacaaatt atgccatcac aaaaagaatc ttcactgcat
    10921 ctccatgcaa tagtcgctcc cacgctatac ccagcaacaa atacatattt atactctgat
    10981 tttaaatcat ttataagctt ttcaactttt ttataaatat caaaaccaac attatttata
    11041 aaaaaatcat atgcctcttg gacttttgaa tatggaaaaa ctcttttttc tcccagaagt
    11101 tcaggacaaa atacatcata tccatattta taatactttt gacaaacatc ttctataaag
    11161 ctattaatcc catagatttc atgcaaaaca acaatagcta catcactttt atgtatatac
    11221 tttatcagat tatccaccac ctttacaaaa cagcaaattt tttatactta gtttaatata
    11281 ttcttcttta catgtcaatt tacttttcta aaatcaaatt tatttttgga ttaatcattt
    11341 atttttaaaa gttgtgcatt attactatta aattattctc tattattaaa aatataatcg
    11401 ttagaaataa aaaataaagt acaaataatt aaaaaatatc tcactcataa ctttaaaaat
    11461 tataagtgag atactcctaa aatctacttt atattaaatt tattttccaa aatatctatt
    11521 taataatcct aagaatgctt taccatgtct agcttcatct ttacacattt catgtactgt
    11581 atcatgtata gcatctaatc ctaattcttt tgctttctta gctaatttta attttccatc
    11641 agttgcacca tactcagcat caactctaac tcttaagttt tcttttgtat ctgcaactac
    11701 aacttctcca agaagttctg caaatttagc agcatgttca gcttcttcaa gagctattct
    11761 cttataagct tctcctactt ctggataacc ttctctatca gcttgtctac tcattgctaa
    11821 atacattcct acttctgtac actcaccaac aaagttagct cttaatcctt cgattatttc
    11881 ttcatctaca ccttgagcta ctcctattct gtgctcatca gcccaatttt tttcgccttt
    11941 catttcttca aatttatcag ctccaacttt acatactgga cattgtgctg gtgcagtatc
    12001 tccttcatgt atatatccac atactgtaca aacaaatttc ttcataatta ctttcctcct
    12061 aaattttata tatcaaatta aattttttat ttattaagtt agtctatata tacccgcacc
    12121 atataccttt aaacaatttt tttaaaagtt ttttctaaat acctattttc cctgtgtcaa
    12181 taatatgttt ctataataat gtccctttaa ttttatcaat tctttatgat ttcctgattc
    12241 cacaattcta ccattttcta aaactattat attatcacaa tttgatatgg tacttaatct
    12301 atgagctata attatacttg tctttccata agttaaatta tttattgctt cttgaatttt
    12361 agcttctgtt gctatatcta tgttacttgt agcctcatcc aaaataagta ttggagcatt
    12421 ttttaatact gctctagcaa tacttattaa ttgtttttga ccttcactta aatcttcacc
    12481 cctatccgat aatatagtac tatatccttc acgcatttta actataaatt tatgtgcatt
    12541 tgctatttta ctagcatata taacttcttc atcagtagcc tccagatttc cataccttat
    12601 attttccata actgtatcat tgaatatata accttcttgt ggaactactc caaaacaagt
    12661 tctcaaatag tttctgttaa tagagtatat atccttacca tctaaaaata tacttccttc
    12721 atctatatga taaaaatttg taattagatt tataatagtt gtttttccac ttcctgtctc
    12781 tcctatgatg gcatttgatg tgccagcttt gatttttagg tttatattat ctaaaatttt
    12841 cttttttgaa tcataagaaa aacttacatc tttaagctca atttctccct ttacaaaatg
    12901 agagtttaaa ttaccatctt tattatcgtt aatctcactt ttaaacatgt tatgcacttc
    12961 ttgctcttct tgttcatcta taatttcaaa aactctttca catccagcta tggctgaaag
    13021 taatgtatta aatagatttg ctaattcatt taaaggtctt gtaaattgtc ttacataact
    13081 taaaaaacta gctataaccc ctatggttat aatatcttta gatgcaagaa tgcctcctat
    13141 aatacatata gttgcaaatc ctatattact aatcacattc ataataggca ttaaaagaga
    13201 agtgtaaatt tgcgatttaa gggaaatatt tagaagtcta tcattgactt ctttaaaatc
    13261 atttacagat tttctttcat aattaaaaga ttttactaca tttatgtttg atatcatttc
    13321 ttcaatatgt gcatttagtt ttcccaactc aacttgttgt tgcttaaaaa aaactctagt
    13381 tctctttgca ataaaattac tcacaaacat tactatcggt attaatatta cactgcaaaa
    13441 ggttaaaatt gggcttaata caaacatcat aataaaagtc atcaatatgt ttaagattcc
    13501 tgtaattaac tgtactaatg aatttgatat tcctgtactg atattatcaa catcatttgt
    13561 cactctactc ataatatctc cagtagaact tttatcaaaa aaggttattg gtagattttt
    13621 aaattttaaa aataaattac ttctcatttc tctgactata ctttgagata atctagctgt
    13681 acatatcccc ttagacagtt taactgaaaa ctcaattata taaaatgaaa gtaaaataat
    13741 tattcctttt aagaaaatgg attttgaata agtatcgata tctattatgt caactacctt
    13801 tccaatagta tatggtatta cagttgatat aattgaatca attattacta gcaaaaaaat
    13861 aaatctagta atcttcttat cttttttaaa gtacataaaa attcttttaa acgttttttt
    13921 aaaatcttta ggcttttctt ttttctttaa tctactgacc ttctgatttc cagtacttaa
    13981 attcaatata cttcctcctt aatttacatc ttcacttact aaattttgca acgcaaaaat
    14041 ttttttataa attggagaac taaccagtaa atcttcatgt gtagcaaatc caaccacctc
    14101 accctcatcc aagactaaaa tcttatcaca gtcaattata gaactaatct tttgtgaaat
    14161 agttattaca gtacatttct tactttcctt ttctcttaaa ttacttatat actcttttat
    14221 attctttctt ataattgttt ctgtattaat atccattgca ctaaaacaat catcaagaat
    14281 caatatttgt ggttttttgg ctatagctct agctatagta attctttgtc tctgtcctcc
    14341 tgataaattt ttaccccttt ggaataaaac ttcatcataa gtattttcga gttttgttat
    14401 aaattgattt gcatttgcta tttcacatga ttttacaaca tcctctttgc atatatctct
    14461 atttcccata actacattct ccaatatact ttttccaaac acactactat tttgaaatac
    14521 tacacctatt cttttcctta aactttcttc agaaatactg tatatactac gtcctccaat
    14581 cttaatatca cctttatcaa ttatatataa tttttgaatt aaatttacta aagaagtctt
    14641 tcctgaacca gtttgaccaa tcacaccaat attttgacct tcttctattt taaaggatac
    14701 gttttttaat attttttcat ctgtattttt gttatatgaa aaatctacat tttcaaaaat
    14761 tatatcacaa tttacaaact ttaaatcttt ttctccaaca tctaaacttt cttctctctc
    14821 aattacttct tcattctcat caaccaaaac ctcacttatt ctctcataag atgcttttgc
    14881 cctaacaaaa acattaaaaa catgtgaaat cattataaga gatgttaata ttctagtcat
    14941 atagtttaca taagcaacta taatcccaat tttaatttct cctgaataaa ttaaatgcct
    15001 tccaatcagt aatattatta ttatggaaac attaatgatt attgtaattg tcggtctaaa
    15061 aaatgacatc atagttgtag cttttctact atttttaaaa agttcatcat ttaactcttc
    15121 aaagctttgg ttctcataat cgtatctaca aaatagttta actactttta ttccacttaa
    15181 aaactgtctt aattttgaat ttactttatc tgtactttct tgtacatttt taaataatct
    15241 ataccctatc ttcatattaa gcaatattat aataaatata attaaaactg caattagaat
    15301 aattattgac atctttaaat ttaattttat agctataatt aaacttccta tacacattat
    15361 tggtgacttt ataaaaactc tcatcattcc attaacgaat tgttgcattt gattgatatc
    15421 attagtaatt cttgttatta atgaagctct accaaattta tctatttgtt ttaatgagta
    15481 tgtatttatc ttttcaaata catcctgtct taaatcataa gaaaaatgct gagaaactct
    15541 tgccgagatt acacttctta ttattgcaaa tattgcacct aaaaaagtta tacctatcat
    15601 tatagctcct gttgatagta tgtagtctaa gttcttattt gaaaccccta tatctattat
    15661 ttttgccatt atagttggtt gagctaaatc acaaaaagct tccaatgtta aaaaaaatac
    15721 tgctgttaga aataatacta tatatttttt tatgtatttt ttaaaatacc tcattcaatc
    15781 atcccttcat agaattttct cattaccaaa agtatatcat aatggctaat ttaattgatt
    15841 atatcaatta taaatatttg atttattatt aatttttata ccatatattt tataaattat
    15901 t
//
LOCUS       DAEPUT010000092        15891 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.094, whole genome shotgun sequence.
ACCESSION   DAEPUT010000092 DAEPUT010000000
VERSION     DAEPUT010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15891
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.094"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            67..609
                     /locus_tag="KRL22_003178"
     CDS             67..609
                     /locus_tag="KRL22_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1273623.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            937..2430
                     /locus_tag="KRL22_003179"
     CDS             937..2430
                     /locus_tag="KRL22_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1273624.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELTDIEKSRITHGKVLFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            2504..2737
                     /locus_tag="KRL22_003180"
     CDS             2504..2737
                     /locus_tag="KRL22_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273625.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDITG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            2893..3657
                     /locus_tag="KRL22_003181"
     CDS             2893..3657
                     /locus_tag="KRL22_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1273626.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(3942..7121)
                     /locus_tag="KRL22_003182"
     CDS             complement(3942..7121)
                     /locus_tag="KRL22_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1273627.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            7402..9579
                     /locus_tag="KRL22_003183"
     CDS             7402..9579
                     /locus_tag="KRL22_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1273628.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKNLIDREYIE
                     KYVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASVRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            9593..10015
                     /locus_tag="KRL22_003184"
     CDS             9593..10015
                     /locus_tag="KRL22_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1273629.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            10423..11226
                     /locus_tag="KRL22_003185"
     CDS             10423..11226
                     /locus_tag="KRL22_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH1273630.1"
                     /translation="MKKLKLIIMFALVSALLVTGCSSGNNKNKEEQKVIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMIEPPIQFGAC
                     SFALQKNEKGEKWTKEINEVIEEMYKDGTLTKISENWLGKDITKEPINE"
     gene            11219..11887
                     /locus_tag="KRL22_003186"
     CDS             11219..11887
                     /locus_tag="KRL22_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH1273631.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     RRAY"
     gene            12123..12785
                     /locus_tag="KRL22_003187"
     CDS             12123..12785
                     /locus_tag="KRL22_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH1273632.1"
                     /translation="MAFNMKYFLELFPTIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDTGQIEAAYAIGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            12845..13642
                     /locus_tag="KRL22_003188"
     CDS             12845..13642
                     /locus_tag="KRL22_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1273633.1"
                     /translation="MIKRNIIKCLVAVLSLTFVITGCSKKEEVKNEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVATSVNKD
                     NLFQEKVYGDGTSGLQDLDLGRVSAWIDAELTIVGDAKKANMKVRVLDKKLSATNIAY
                     FFKKNDDKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            13760..14950
                     /locus_tag="KRL22_003189"
     CDS             13760..14950
                     /locus_tag="KRL22_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1273634.1"
                     /translation="MEVLQMIETKIKSIALKNREKIIKIRRQIHSNPELAFKEYKTSK
                     LIKEELNKLNIEYINIAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSIN
                     DNMHACGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGV
                     DALATGHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAV
                     YSSIQQIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKI
                     LEYIVKNVCKAHGADCKFEKSTGGDAVINDKNMIEIGRESACKILGAENVEIIDFPAM
                     TGEDFAIYMKEKPGLFMYIGVGDKEKNINYRLHSNKFNIDEKCLSIAPSLFSQLTVDY
                     LCQL"
     gene            15059..15808
                     /locus_tag="KRL22_003190"
     CDS             15059..15808
                     /locus_tag="KRL22_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH1273635.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEISQSEVVAILGSSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDITNLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSKKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIRKEEVFS"
BASE COUNT         6168 a         1673 c         2643 g         5407 t
ORIGIN      
        1 agtaataact ttaaaattat attactatta tataaaaatt ggcttaaaag aaggtgaaaa
       61 aagtaaatga aaatatgcat aacagtaggt catagtatac taaaaggtgg taaaagtaca
      121 ggtgtaaatg gtatagttga tgaatacaat tataataaaa aattagctcc tatgttagct
      181 gagatgctta taagtcaagg taatacagta gatgtaataa tttgtccaga aaggcacttt
      241 atgtcagaaa gagaagaatt tttctataga gttccaaaag taaacagtgg taaatacgat
      301 ttattagtag agctacattt aaataaagct gatggaacac aatgtggtac agaagtgctt
      361 tactatggca ctgaaggatt agaatatgct aaaagagtat ctaatagact tggagaatta
      421 tttgaaaata gaggagctaa aaaaagagaa aatttatata tattgagaaa tacaaatcca
      481 gttgcaatac agattgaaag ttttttctgt gataatgtga atgattgtaa caaagcaaat
      541 gaatcaggtt atgattatat agcacgattg attacagaag gtatattgaa taaagatata
      601 aatatgtgag attatggtga tttaggtatt gattaatacc ttttaatatt agatataaat
      661 aaaaatacaa tgtattagta taatttaaac tttcaaaaga tagattagtt tgattattga
      721 caagagatac ctccttgaaa atattgattt atcagtatat ttaaggaggt atttaaatat
      781 aaaaatttaa ttaatttgct actaaactat aggtttatag agtatatact tttatcttca
      841 gtctaataaa taatataaaa atagtagaac cttgtattat aataatataa tgtagaaaaa
      901 tatatagata agataaatat aataaggtgg taatatatga aatatacatt tgaaaaattt
      961 aagttaaatg aaaagatact taagtcattg aagagtttag gatataatat accttctaga
     1021 gtacaaagag aagttattcc aaaattatta aaaggtcaaa acttagtagt taggtcaaaa
     1081 acaggaagtg gaaagacagc aagttttgca atacctttat gcgagaatat aaatgtagat
     1141 tacaataata ttcaagctct tatagtggtt ccaacaagag aattagcctt gcaagtaaaa
     1201 gatgagatat cagatatagg gagactaaag aaggtgagat gtagtgctat atttggcaaa
     1261 caatctataa aagaccaaat agctgaattg aaacaaaggg ttcatattgt tgtagctact
     1321 ccaggcagaa tacttgacca tataaataga ggttctatta agttggaaaa tgtaaagtat
     1381 ttagtaatag atgaggcaga taaaatgttt aataaaggtt ttgttgaaca aatggaaaaa
     1441 atattattaa atttacctaa ggagaaaata gtaagtcttt tttcagctac aatagatgaa
     1501 gagataaaat atatatgtga aaaatatatg ctagattaca gtgttataaa tatagaagaa
     1561 aatgagagtg atactaatca aaaaacaaga caaatagatg acaaaataat caaggcaaat
     1621 ggaagagaga agtacatcct tttaaaagaa ttaatataca gcgaaaatcc aaagagtgtg
     1681 ataatatttt gtaataccaa agagaaagta tctaaattat ataataagat gagtaaagag
     1741 ggttttttaa taagagagtt acatgcagat ttatcacaag aaagaagaat ttttgtaatt
     1801 aaggatttta aaaaccaaaa atttaatata ttagttagta gtgatgtagc gtccagagga
     1861 atacatattg atgatatttc tttagtaata aattatgatg taccacaaga taaagaaaac
     1921 tatatacata gaataggtag aactgggaga aaaggaaata gtgggaaggc aattactata
     1981 gtaactgaaa aggatgaaaa atatatagag aatatagaaa catatatagg atataaaata
     2041 aatgaattaa cagatataga aaaaagtaga attacacatg gcaaagtttt gtttgaagaa
     2101 tattcaaaag gaatcctaaa aaaagtatca aagagaaaaa aagttgataa aaattcttac
     2161 aaaagtaaag atataaaact aaatatagaa agtgaagttg ttaaattata tttaaatgct
     2221 ggtaagaaga agaaaataag agttttagat atagttggtg catttagtaa tataaaaggt
     2281 ataactaatg atgatatagg tgtaattgaa gttcaagatt tatgttcata tgtagatata
     2341 ttaaattata agggagattt gatattaaaa aaatataagg agatacctat aaagaaaaaa
     2401 atggttaaag tgaaaagaga tatacgataa tttagtcaat attgatgaat tgctttgtta
     2461 tcgaaatgaa gttgcaaaaa acacaataga agttgttaag gatttgaaag ctgaagatat
     2521 gaaacgaaag gtctctccaa ttgacttaga aaggattttg gtgactggag gagtaataaa
     2581 gcatgaagat tctatttggt tgttggactt ttgggggaat aaagatatta ctggaatttt
     2641 gcttatgcct cctactcgtc atgttatact tcatttgaat gattgttgta aatggaagga
     2701 atattttcgt acaaaaaaga aattttacag aagttaaatt ataataaatt agacaaacaa
     2761 tagataaatt agcaaggaat gttgatttta tctacattct aagttatact atttttaagt
     2821 ggctaaggga atagtcattt taaatataag taataaatat atacctatag ggatattaaa
     2881 ggggggaaat atatggcata ttttaactat aacgacaaac agtgctacta taatgaaatt
     2941 ggggatggta caccattact ttttttacat ggaaatacag cctcttccaa gatgtttaat
     3001 gatataatcg atttttataa agatgaatat aaagtaatat taattgattt tgtaggtcat
     3061 ggaaaatctc aaatggtcga taaattttct gctgacttat ggtttgatga ggctatgcaa
     3121 gtgatatgtt ttttagaagc aatgaactat aaaaaagtaa acataattgg tagtagtgga
     3181 ggcgctcttg ttgcattaaa tgttgcactt gagagacctg atttagtgaa taaggtaatt
     3241 gcagatagtt ttgaaggaga agttcctcta gagtcatttg tacaaaatgt gaaaatagag
     3301 cgtgaagcat ctaagcaaga tgatggtgca aaagcttttt atatttataa tcaaggagaa
     3361 aactgggaaa aagttgtaga taatgataca gaagctattt ttgaacatta taaaactata
     3421 ggaaagtttt ttcataagcc tctagaaact atgcaaccag aggtgctttt aacaggaagt
     3481 agagaagatg agtttgtatc tctaatatct agtgattttt ttgaaaatac tttttcatta
     3541 cttcttgaaa agattaaaaa tggtaaaatg tatttgtttg ataaaggtgg tcatcctgca
     3601 attttatcga atggattaga tttttcaaat gtagcaaaga aatttttaga ggaataattt
     3661 aaccaaaatt tacaataatg aaaactgtaa aatggattgc aaaacttaca aaagtgagtg
     3721 tacatatact tcattattat gatgaaatag tattgttaaa acaaaatatt ctaatagtca
     3781 agttattaca tttgtatatg caatatgtat agaaagagat atcattagat tgtaaagttg
     3841 ggattaaata acaatattaa attttattta ttcagatatt ttagcttaac tatataaatg
     3901 ttagaacaaa tttatatagt taagctgtag gattaaataa tttagttaaa taagtttatt
     3961 atctcctcat cagatagact ttttaataca ccttcattag aaagttctcc atttataaat
     4021 tgatttataa gctctttttt actttcttgt aattttatta ttttttcttc tatagtccct
     4081 ttagcaatca attttataac ttgtactgaa tttttttgac caaatctatg agctctatca
     4141 ctagcttgat tttctactga tggattccac catgggtcaa agtgaattac catgtcagca
     4201 gatgtaagat ttaaaccagt tccgcctgct tttaaagata ttaaaaaaac ttttttatcc
     4261 atactattat tgaactcatc tacaagttca agtctttctt tggcattagt tttaccatct
     4321 atataatggt atttaatttt atacttatca agttccttac ttatgttctt aagcacagaa
     4381 gtaaattgtg aaaacaataa tattttgtgg ttttcgttta tactatccct aagtatttct
     4441 aaacatgttt caatttttga acttttttta ttgtaatctt ttactactat acttgggtct
     4501 aaacaaagtt gtcttagttt agttaaataa gaaaatataa ctattttatc tttctttaga
     4561 tttttatctt tcattttatc ttgtatatct tttgaatata cactatatat ctttttctgc
     4621 tctttattca attcaacaaa aaagtttttt tcaatcttat ctggaagttc tttcataact
     4681 tgttttttac ttcttctaag aataaaaggt tttatcaatt ttttcaggtt tttaacatta
     4741 tcttctttat ttataaacaa ttcctgaaac tttgctttac tatatagata gccaggcatt
     4801 ataaaatcaa atatagacca taattctagt agattatttt ccataggtgt accagtgagt
     4861 gcaaatttat tttctgcatt tatacttttt acagactcag ttactaaagc tactggattt
     4921 tttatatttt gagcttcatc taatatacaa taatcaaact ttatttcact atatttttct
     4981 aaatcatttc taagagtacc atatgttgta agtattacat caaaattttc taattccata
     5041 aaacattttt ctctatctct tttatttcca tgtatcaata aaacttttat atctggagca
     5101 aacttttcaa attcattttt ccaattataa atgagtgatg tcggtgtaac aataagactt
     5161 tttttattag ataatgataa taaaaatgca atagtctgta ttgttttacc aagacccatt
     5221 tcatcagcta atataccacc aaatttataa taatctaaaa ctttaaacca attgaggcca
     5281 tttatttgat agtcacgaag gtttgcattt aaatttgcgg gaatttctaa atttatgcta
     5341 tcaaaatttc taaatttttc acatatactg tctagttctt ttttaccatc tataaacttt
     5401 aaatttttac tacgtattac atcatttata tatagagctt tatttttatg aattttatta
     5461 ttttttgatt tatccattat atctagattt tcaactaatt caaaaaaatc ttttgtttct
     5521 ctttctgata aatctataaa gtttccatct ttaagtttat aaaaagtacg tttttcttga
     5581 aaagctttca aaatatcctt gtactctttt ggatttatat cagatatatt aaaattaaat
     5641 tctaggtaat tctggttagt ctgattgatt gaagcttgaa ttgatgaagc gttatatatt
     5701 tttttcaatt taaacttctc agaataatat atatctccaa attcctttag agattctaat
     5761 tgtaaatcta aaaatgtaaa taggtcatgg tcagttcctt taaacacata atgattattt
     5821 tcctttgtaa attgtgaaga agtaagttta ttttcaatag tagcttcctt ttgtatgttg
     5881 gggagcacaa attttttatc ttcatcatca tatatatact ttacatcaca acatatgttg
     5941 ccatcaatca tatcaaagta gaactcagat ttaaaatctt ttgttatatt attttttatg
     6001 ttatcatcta aatgaacttc ttgagatata gattttaatc taggaactag caatcctaaa
     6061 acatccttag aatcctcttt atcaaatttt aactctttag tctttgataa tatttgatat
     6121 atttttgaat aatcatgagc ttttttatgt gataataaat agatattgcc atcatataaa
     6181 agtacatcat tttttttagt aagtggaaca ggtagtgaat ctttagaata taagactatt
     6241 ttatcttcta tatttttaaa atcaaacctt acaggtagag tatcatttaa tatctttgga
     6301 tgatattcct ctttagaaaa aataagggta aaatccttgt acttaatagc atttaaaaat
     6361 tgttttaaag agcttgcatt tatctccata aatttttttg aatgtgatga agaaaagttg
     6421 tatgaaagat ttgtcccata ttcttctata atatctacta acttctcatc ttcatcagca
     6481 aaataatgag tgttggggtt gtaagtaaat ttcttcccaa aatctaattc atatccatta
     6541 agttttgaat atgcaaattc agtaatgttt tttaaaatgt acattttatc aattcctatt
     6601 ttaaattcag caattgcttt atttgaatcc acatttatca atacatctaa attaaccctt
     6661 tctcttttag tattgtctaa caaagaaagt aattgcttgc ttaaatctaa gctggtttta
     6721 gaatttgtat tagaaagctt atccttatct gcacctaata tatctattag aataggagga
     6781 acatcttttt tattttttat ttgttttaag ctttttatca caatagcaac tatatgctta
     6841 catataaaaa tacttttgcc ctttgattga cagtcagcgc aactacaatc attttcaatt
     6901 atcttaaagt gctttatatc tatagttatt gaattaaaat aaaagctata attatcttca
     6961 gaattgactc caccacgaaa tgtcaacagg ttattttgta ggtcatcaat atctatgtct
     7021 atataatcaa ctaattgatt agtataatat tttacacctc ttgaccatct tgatggttct
     7081 gtatttcttc ttattagttt atatatcata tctattttca tattattcac cttacctcac
     7141 tgtatatatt ataatctaaa tgcattcaat ttacactcta aatttaagac taaaattaag
     7201 gcagatatga atagctttta tctatcacaa tatatgtgta aataacaatt tactattaga
     7261 tttttattga attatcttat aaactatgaa tgaaaaataa ttatataaat agattattaa
     7321 taaatataaa atcttattat taaaaatatt cttagaaatt acactatata aaatataaag
     7381 tatgatattt gaataaaaag aatgtataat aagtataata atttgtattt attattggga
     7441 aaggaaaatg ttaatatgga tagttataga caacttaaag ctaaaatacc ctgtaaggaa
     7501 acaggtatag aaataaagag gactttatgt gatatttgtt ctccaggagt acattgtgga
     7561 attgatgcat atgttaaaga tggtaaagta ataaaaatag aaggtacaaa agaacatcca
     7621 atgaataaag ggttgttatg taccaaaggt ctttgcaata gagaatatat ctatagagaa
     7681 gatagaataa aaacacctct aaaaagaatt ggaaaaagag gtgaaggaaa atttaaacca
     7741 atatcatggg atgaagctta tagagaaata gcagaaaaat taaatagagt aaaatctgag
     7801 tatggagcaa agcatgtagc tttttttacg ggttatggaa agtggtatag acctttttta
     7861 caaaggtttg catcttcatt tggttcacct aattatggta cagaatctag ttcatgttca
     7921 acatcagcac agatggctgg aaatgttgct actggaagaa actttacaat gcaagatatg
     7981 gagaatgcaa aaacttattt agggtgggga tttaatccat actactctaa atttttaaat
     8041 agtgtgaatc taataaaatt aaaagaaaaa ggtctaaaat ttataattgt agaccctaga
     8101 ataacaccga caactcaaaa actagcagat ttacatttaa gaattaaacc tggaactgat
     8161 ggagctttag ctcttggaat ggcgaatcta tttatacaaa agaatttaat agatagagaa
     8221 tacatagaaa agtatgtaca tggatttaat gaatataaag aatatgtaaa attatttgat
     8281 ttagatactg taagtagaat tacaggagtt tctaaagata atatagtaaa agctgtcgag
     8341 atgttgtcac aaggtccatt ttgtataaat gaaagtgcag ctccaatagt tcatcatcaa
     8401 aatggatttc aaaactatag agcaatgatg tctttatccg ctataacagg taattatgat
     8461 agaataggtg gaaacatacc aaaacaagat tactttgctg gtaagatagg tggattccaa
     8521 acactagaaa aagagtttgt aaaagaagtt ctacctaaaa atataaatga aagaattggt
     8581 ggagaaagat ttcctctatg gaatgaaatg gtgactcaat ttcaagctat ggatttacct
     8641 aggcaaatag aagaaaagac accatatgaa ataagagctt tgttttgtca tgggataaat
     8701 gctagaatgt ttcctaattc agggagactt tttaaagcgt tgaatagtgt agattttttt
     8761 gtgaatatag atttatttat gacagataca tcaaaatatg cagatatact tttacctgca
     8821 tgtacatcat ttgagagaga agaatgtaag agttatccag gagggtatat tacatatacc
     8881 aaaaaagtta ttgataaatt atacgattca aaatcagatg tagaaatact ttcagattta
     8941 gcaaatgcta tgaatataga tgatgattta ttaaaagcag gttatgaagc aagtgtaaga
     9001 catatgttta aaaatacatg tgtagatgta gataaactta aagaaagtga tttaccatta
     9061 aaatgtaaag attttaagcc atatatagta ggttcatata caagagaagg gtatgatact
     9121 agcacttcta ggtttgaatt aaaatctacg attattgaaa aatataaaga ttttgggctg
     9181 gatgcactac caacatatag aggatttaat gataatatag atgatgaata tactcattta
     9241 ttgacatcag gagcaagaat ttcaaatgca ctacattcaa gacttcatga catcaaactt
     9301 tcaagaatat taaaaaatga agctagttgt gatatttcta gcttagatgc aaaagaattg
     9361 ggtgttatca gtggagatta tataaaaata actactaaga taggaagttt ggatgtaaaa
     9421 gtcaatgtta ctgatagagt cttatataag aatatacata tgtatcatgg atatagagaa
     9481 gctgatataa atagtattat ttgtgataat tttgaccctt atagtggatt ccctgcgtat
     9541 agaagttgta agtgtaagat tgaaaaaatg aatagataaa tggagagata taatgaaaag
     9601 tttatttaaa tttaataaag aattatgtac agcatgtgga gcatgtttgc ttgcatgtat
     9661 agaccaaaat gataataata tagacaatgg tgaacttttt agacatgtat ttacaataga
     9721 ggaaggtgaa aatatagaat atttttcatt agcatgtata cattgtaatg agccaaaatg
     9781 tttaggtgta tgtcctaaaa attgttttaa aaaagaagaa ggattcgttg tattagacaa
     9841 tcaaaactgt atagggtgta aactttgtga aaaagcttgt gaatatggag ccttaattta
     9901 tggaaatgat ggtaaggcaa ataagtgtaa tggttgtatt gagagatata agtgtggtat
     9961 ggattcacct tgtgtaatgg tatgtcctac aggagcatta aaatttaata aataaattaa
    10021 atatagagaa tgacttatac ttaggtataa gatattttta caaaaagctg tattgagttt
    10081 gttataatga aaactcaata tagctttttt atggatatag ttggatacta taatgtgatt
    10141 cttagtaata gttttttgct attggacaaa gactgtaaaa catattaaac ttatgttgtt
    10201 caaagtcgaa gtataatata ataactagaa aattggttta tagtgctata aaagcaaatt
    10261 tagtaaggta taaaatcaga ggcaatcctt tactataata tcaatatttg ggagttctgt
    10321 tattgcagag ctattaaaca attataatgg tacaagtgat tcaacctttg aaaatgtatt
    10381 atataaaaaa ttaaaataag attaaaaagg agagaataaa ttatgaaaaa acttaaatta
    10441 attattatgt ttgccttggt atcagcactg ttagttacag gatgttcatc aggaaataat
    10501 aaaaataaag aagaacaaaa agttataaga gttgcaacat caggaacata ttaccctttt
    10561 gcttttaaag ataaagataa acttaaaggg tttgaagtag atttttggga tgaatttgct
    10621 aaacgaacta attgtaaagt tgaatgggta ttaactgatt ttagtggatt atttggatta
    10681 ttagaagctg ataaagcaga tgttgtatct gctcaactta ctgcaacacc tgaaagagag
    10741 aaaaaatatg ctttttcaga tgcttataat tatagtggaa caaacattat tgttagagaa
    10801 gatgatacta gtataaaatc aatagatgat ttagttggca agaaagtagg tgtgggtact
    10861 ggagcagtag caaatgaaat attaaaagaa aaatacccaa atgatgaaat aaaaatagta
    10921 aattattcaa gtgcgactct taaagggaat tatcaagacc tagaaatggg aagattagat
    10981 gcagtagttg cgcaggatgt tgaggcttta atagctataa aagaacaaaa attaaatctt
    11041 aaaatgatag aacctccaat tcaatttggt gcctgttctt ttgcgcttca aaaaaatgaa
    11101 aaaggtgaaa aatggacaaa agaaattaac gaagtaattg aagagatgta taaagatggg
    11161 actttgacta aaatatctga aaactggcta ggaaaagaca ttactaagga gcctattaat
    11221 gagtaatttt aattttgaat tttgtctaag tatatttcca tttttgatta aagcattggg
    11281 aataacaata ctaatatcta ttgttgcatt ttttttatca atattattag gtgtaatact
    11341 tgcctttttc acacagacaa aatcaaaagt tttacaatac ataacaagag tgtatgtttc
    11401 attctttaga ggaacaccac ttttaattca aatatttttc ttttattttg gatttccaat
    11461 gatattttct tttatgaaag attgttcacc ttatttagca atagtaattt gtttaggtgt
    11521 aaattcatct gcatatatgg ctgaaattat acgagcatct attgagagtg ttgataaagg
    11581 acaacaggaa gcatgttatg cttttgggtt aagtaaatat cagtcaatgg ttaaaataat
    11641 tctacctcaa gcagctacat ctgcagtacc tcctattgta agctgtacac tggacataat
    11701 taaaggttct tctttaggtt taactatagg aatacaagat ttaatgggag tagctcaagt
    11761 agaggctgct tcaagtttta aatattttga gatatatatg ataacgatat taatttactg
    11821 ggcagtatct ataatattga gtaatataca aagcaaagtt gaaaaaagaa taagaagagc
    11881 atattagatt tcaatattta aaaatgggat gatatagata tattattact tgtaaataaa
    11941 tttttaattt tagaaaaata aacttagtaa tctaaattat tgagaaaata tagtatcaaa
    12001 atggactgta taatcaagtt aaaaaatagt ttttctattg aaaaaataaa taaaattcta
    12061 ttgtaattta atatgcgata aagttttata aaaaacaaca ttaagctagg gggacttatt
    12121 ttatggcttt taatatgaaa tattttttag aattatttcc aacaataatg aaatcgttca
    12181 atgtaactgt gattttggca ataagttcat tagtattttc attaattata ggtacaatag
    12241 tagcgttatc atcttattac aaagtgaaag tattgaatca aatatgtaaa gtatatgtat
    12301 ctatttttag aggtacacct cttatgccac agttattctt tttatatttt ggactagcat
    12361 atatgagtga ttttgttaaa aatatggacc cagtatttgc aacatctata gtacttagtt
    12421 taaatatggg agcttatatg tctgaaacga taagggcatc tatactttca attgatacag
    12481 gtcagataga agcagcatat gcaataggat taacaaattt acaaacaatg aaaaggatag
    12541 tgataccaca ggccgtaaga gttgcactgc catcattatt caataatttt atagatttaa
    12601 ttaaagggtc ttctgtagct tttgttgttg gagtaaatga tataatgggt gctgccaaat
    12661 cacaaggagc gttgagtttt aagttttttg aagtgtatgg agcagttatg gtaatttact
    12721 ggtgtataat aactccttta ggttgggggc aaaaaaaatt agaaaagaaa ataagcaatt
    12781 attaagttat taagaaaata cataaaagta tttttatata aaaaatggtg tgaggagaag
    12841 agatatgata aaaagaaata ttataaaatg tttagtggca gttttatcgt taacgtttgt
    12901 aattactggt tgttcaaaaa aagaggaagt aaagaatgaa aaagttataa ctgtagcttc
    12961 atctaattca gctgacccat attcttatgt tgataatggt gagcataagg gttttgaagt
    13021 tgacatgtgg aaagagattg gtaaaagaag tggatataag ataaaaatgg aaccaacagg
    13081 ttttagttct atatttggta tgttagattc tggtaaagtt gatgtggcag ccaacttctt
    13141 tggaatgtct aaagaaagat tagaaaaata cgatgcttct ataccttatg gttctgattc
    13201 tgtgtgtata gctgtaaaag atggaaataa cgaaattaat aagcttgaag atttaaaggg
    13261 aaaagttgta gcagtttcag aaggttctca aggtcaacag gttgcaacta gtgttaataa
    13321 agataatttg tttcaagaaa aggtttacgg tgatggaact agtggtcttc aagatttaga
    13381 tttgggaaga gttagtgcat ggattgatgc agagcttact attgtgggag acgctaaaaa
    13441 agctaatatg aaagtaagag tattagataa aaaattatca gctactaata tagcatactt
    13501 ctttaagaaa aacgatgata aatctaaaac gataaaagaa gatgtaaaca aagcaataga
    13561 agaaatgctt gcagatggaa cagtgaaaaa aatatctgaa aaatggtttg gaatggatgt
    13621 aagtgctgat atacaaaaat aaatacttta aaattaaaat gtaaaactgt gataactata
    13681 gataagtata ctaaatttat ctatagttat ctgtgtatta caatgtattt agattagtct
    13741 ttataaatca aaatgagtta tggaggtatt gcaaatgatt gaaactaaaa taaaatccat
    13801 tgcactaaaa aatagagaaa aaattataaa aataagacga cagatacaca gtaatccaga
    13861 gttagcattt aaagaatata aaacatctaa acttataaaa gaagagctaa ataaacttaa
    13921 tatagaatac ataaatattg ctggtacagg agtattagct actataaaag gaaaaaataa
    13981 tggtggaaaa actatattac tcagagcgga tatggatgct cttccaatca aagaggaaaa
    14041 tgatttagaa tttaaatcaa taaatgataa tatgcatgct tgtgggcatg atgcacatgt
    14101 ttcatggttg ttaggaacag caatgatttt aaatgacata aaagaagaat tgaatggaaa
    14161 tgtaaaatta ctatttcaac ctggcgaaga aaaaggtggt tctgatattg taattaaaga
    14221 aaatgtactt gaaggtgtgg atgcattagc gactggtcat tgttggccaa ctattgagtc
    14281 aggaaaaatt ggaatcgcta gaaattgtgc tatggcagcg actaatactt ttgaaataac
    14341 aataattggc aagggtgggc atggagcaga gcctcataat tgtatagacc caattgcagt
    14401 tggaaatgca gtatattcat ccattcaaca gatagtttca agaaaaattg acccagttgt
    14461 acctgtagta gtgtctgttt gttcttttaa ttctggtgtt tctaaaaata taataccaga
    14521 tgtatgtaca cttcaaggga ctattagagc gataagcaag gaacaagtaa ttgaagtaag
    14581 taaaattcta gaatatatag taaaaaatgt atgtaaagca catggagcag attgcaaatt
    14641 tgaaaagagt acaggaggag atgctgttat aaatgacaaa aacatgatag agataggaag
    14701 agaaagtgct tgcaaaatac ttggagctga aaatgttgaa ataattgatt ttcctgcaat
    14761 gacaggtgag gattttgcta tttatatgaa agaaaaacct ggtttattta tgtatatagg
    14821 tgtaggagat aaagaaaaaa atataaatta cagattgcat agtaacaagt ttaatataga
    14881 tgaaaaatgt cttagtatag caccttcatt attttcacaa cttacagtag attatttatg
    14941 tcaactatag agtacattca taaaaatata tttagcctat ttttaaattt aatgctagta
    15001 tattaatttt gatgtagaac atattattta ttatatttat ttaaaaaggt ggataacaat
    15061 gataaaagta gaaaatttac ataaaagttt taaagggaca gaagttctta aaggtataaa
    15121 tttagagata agtcaaagtg aagtagtagc tatacttgga tcatctggaa caggtaaatc
    15181 tacgttactt agatgtttaa attatttagt tgagcctaca aaaggaaaga taatgattgg
    15241 tgatgtaaaa gtagatgtag aaaaagcaac aaaaaaagat ataaccaatt taagaaaaca
    15301 tacatctatg gtgtttcaaa attataactt atttaaaaat aaaacagcat tagaaaatgt
    15361 aatggaggca ttgatagtag ttcataaaaa gagtaagaaa gaagctagag aaatatcttt
    15421 aaaattaata gataaagtag gtatgttgga taggaaagat ttttatccat caaagttgtc
    15481 tgggggacag caacaaagga taggtatagc gagagcgatg gcagtaaatc caaatgtaat
    15541 attatttgat gagcctacat ctgcacttga cccagaactt gttggagaag ttttaagcgt
    15601 tataaaatct cttgcaaaag aaggtataac gatgcttatt gtaactcacg aaataaattt
    15661 tgcaaaagaa gttgctgata aaattatatt tatggataat ggtgtaatag ctgaagaagg
    15721 aactcctgat gaaatattta ataatcctaa aaatgaaaga acagcaaaat ttttaaatat
    15781 cattaggaaa gaagaagtat ttagttaaaa gtgtataaat taagcattag aagatatgta
    15841 agataccccc attaaattta taagttagat aataaattta atgggagtat a
//
LOCUS       DAEPUT010000093        15768 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.095, whole genome shotgun sequence.
ACCESSION   DAEPUT010000093 DAEPUT010000000
VERSION     DAEPUT010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15768
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.095"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            21..797
                     /locus_tag="KRL22_003191"
     CDS             21..797
                     /locus_tag="KRL22_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH1273636.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(889..1641)
                     /gene="xth"
                     /locus_tag="KRL22_003192"
     CDS             complement(889..1641)
                     /gene="xth"
                     /locus_tag="KRL22_003192"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBH1273637.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(1802..2752)
                     /gene="galT"
                     /locus_tag="KRL22_003193"
     CDS             complement(1802..2752)
                     /gene="galT"
                     /locus_tag="KRL22_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBH1273638.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIESEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            3137..4333
                     /locus_tag="KRL22_003194"
     CDS             3137..4333
                     /locus_tag="KRL22_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1273639.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(4445..5785)
                     /locus_tag="KRL22_003195"
     CDS             complement(4445..5785)
                     /locus_tag="KRL22_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH1273640.1"
                     /translation="MKKRYNIAIVGGGSTWTPGLLKSLCKMSDRFPLNKVTMLDVVEE
                     RQRLIGEFGKILFKEEYPKATLEYTTNPDEAFIDVDFVFVQMRTGGLKMRELDEKIPL
                     QFGLVGQETCGAGGFAYGLRSIGDMIEMVKTVRKYSPKAWILNYTNPAAIVAEALKRV
                     FPDDKRLLNMCDQPVNLLRSYGRLLDMDSRTFEPVYFGLNHFGWFTHLYDKNGEDLVP
                     KIKDLVANSGFQPVDAEQRDKSWLDTYGMVKDMLEDVPDYLPNTYVQYYLYPDKKVAK
                     SNINCTRAREVMNGREKRVFEECKSVIEKGTSIGSNLVHNDAHGEFIVEVAEAIAHNK
                     HQIAIVITENNGAISNLPDDAMVEVAAILTKNGPRPLHVGNIPTFYKGLLEGQLAYEK
                     LAVDAYFEQSYEKAILSLTLNRTIISPTKARQVLDALIKVNKDYWPTLYKENEK"
     gene            complement(5924..6676)
                     /locus_tag="KRL22_003196"
     CDS             complement(5924..6676)
                     /locus_tag="KRL22_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1273641.1"
                     /translation="MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANET
                     FNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLI
                     NVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
                     NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSP
                     QYNFNSVNYTSRVPALSLMEYMFHKYIEKYNR"
     gene            complement(6824..8401)
                     /locus_tag="KRL22_003197"
     CDS             complement(6824..8401)
                     /locus_tag="KRL22_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1273642.1"
                     /translation="MKQKMKGFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSD
                     MPFLANNFIQGILGFTKAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVL
                     HTSVNYMLGCRGILAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
                     KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFV
                     FGFLERLLIPFGLHHILNAMFRFTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFST
                     EATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAGALATFVTGITEPLE
                     FSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSI
                     ILGLVYAIVYYNVFKILILRFNLQTPGREEITDINFDLKPLSNKVEIAQSGETTKRAL
                     SIIKYLGGKDNIEDITNCITRLRVVVKDMSKVDENAFKKYTGAMGVIKVSDKDIQIIY
                     GPSVSQVRDEVSFAMSI"
     gene            complement(8813..9265)
                     /locus_tag="KRL22_003198"
     CDS             complement(8813..9265)
                     /locus_tag="KRL22_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1273643.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(9576..11021)
                     /locus_tag="KRL22_003199"
     CDS             complement(9576..11021)
                     /locus_tag="KRL22_003199"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBH1273644.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(11165..12073)
                     /locus_tag="KRL22_003200"
     CDS             complement(11165..12073)
                     /locus_tag="KRL22_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1273645.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            12330..13154
                     /locus_tag="KRL22_003201"
     CDS             12330..13154
                     /locus_tag="KRL22_003201"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH1273646.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            13194..13724
                     /gene="lepB"
                     /locus_tag="KRL22_003202"
     CDS             13194..13724
                     /gene="lepB"
                     /locus_tag="KRL22_003202"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH1273647.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDENEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(13806..15587)
                     /locus_tag="KRL22_003203"
     CDS             complement(13806..15587)
                     /locus_tag="KRL22_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBH1273648.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRVLFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
BASE COUNT         5337 a         2452 c         1870 g         6109 t
ORIGIN      
        1 aaatttagga gataaacttt atggaataca taattttcga tttggaattt aaccaaggat
       61 ttgataaaaa actcaataaa actgtatcca atgaaaagtg tccttttgaa attatacaaa
      121 taggagcaat taaattggat tctaaattca atataataga tacgtttaat agttatgtaa
      181 aacctacaat ttataaagac atacatccct ttattagtcg tatgactaat attaaaaatt
      241 ctgattttaa tgattcgcct actttccctg aggtctacaa caattttata aaatttatat
      301 catcacaaga ccctatatta tgtgtttggg gagctggaga tttaaaggaa ttatacagga
      361 atatcaacta tcacaagcta ccatcaaatt ccttacctaa atcttatatt aatatacaac
      421 aacatgcatc taaatatttc aataatccag caggaaaaag cattggccta caaaatgcta
      481 tttctatatt agaacttgat gaaaaaatgt cttatcacaa tgctttaaat gatgcatatt
      541 atactgctaa agtttttatt aagatataca atccaagtat agtcccagat atatatcttt
      601 atacaagtat aaaacctaaa actataagat attctaacaa aaaaagagtt gattatgata
      661 agttatttga tgaatttagg aaaattttaa atcgtgaatt aactaaagac gagaaaaaaa
      721 tcattaactt agcttataat atggggaaaa caaatcaatt tacattagaa aatgttaagc
      781 aaagaaaaaa caaatagagt ttatttagat aaaaaatagg catgtagatt aaaaaactag
      841 ttaactttaa atttatatct acagcccaat ttttatcata attaattttt attttatctc
      901 taattcaact ggacaatggt ctgaacctaa tatttcagtg tgtatatccg cacttactaa
      961 tctatcttct aattttttgg atgcacaaaa ataatctatt ctccaccctg cattattttt
     1021 tcttgcatta aatctatatg accaccaact ataaacacct tctttatcag gattaaaata
     1081 tctatatgtg tctataaacc cactgtctaa taatttagaa aacttctctc tttcttcttt
     1141 agtaaaacct gcatttttca tattattttt aggatttttt aaatctattt ctttatgtgc
     1201 aacgttcata tctccacaca caattacagg cttatgatta tctagtttgg ttaaataatc
     1261 tataaagtcg tcttcccatc tagttctata ttctagtctc tttaattcag attgagaatt
     1321 tggcgtatat actgtaacaa agtaaaaatc ttcaaactct agagttatca ctctaccctc
     1381 tttgtcatgt tcttctatat ttattccata cattactttt aaaggctctt tttttgtaaa
     1441 tatagcagta cctgaataac cctttctctc agcataattc caatattgaa aatatcctgg
     1501 taaatctaac tctatttgcc cttcttgcaa tttagtttct tgtaaacaaa atatatctgc
     1561 atctacttct ttgaaaaagt ctaaaaatcc tttcccaaca caagctctta ttccattaac
     1621 attccatgat ataaatttca tacttatact cctcatctaa acattgacac actccccata
     1681 gctaaagatg ggggcttttc aacaatttta ttgtaaattc ttaattcact tttattttaa
     1741 caatgctata ctataatttc atctaaaatt actatttact taatacctaa aaatatatgt
     1801 tttaatcaat ttttaacttt tttgttaaat cttcagggct cattgaagaa acatacatat
     1861 ttgttccaag ttcaaatcct ccaaaattat attttcttgg gattatgtgc atatgaacat
     1921 taaaatacga ttttgtttca atctttgttg gatgagtgtg aatacataaa ttaaatggca
     1981 tatatccatt gatattgtat aacttcttaa acaacttttc aaatattgta gaaagctcct
     2041 gtatattatt atcatttaac tcaccaaact ctattttatc tttaaatatt attcttactt
     2101 ctccactata cttggttgca tatggtataa gtaccaaaaa agcttctcca ttataaacaa
     2161 ctcttctatc taaacttatt tcattttcta ttaaatcatc atacaaagag cttttattgc
     2221 tgtcataata ctcctttgaa accaacagtt cattcgtaat ttcaggtgga ataaaagaca
     2281 tagacaatat ttgagcatgt ggatgcatca aagatgctcc tgcctttctc aagaagtttt
     2341 tgaagatact aacatactct actttatcat ctttcgacaa atctctaaat ctatttctat
     2401 acataaaaaa aacatcttca aattcttttt gactcatgtt ataaaaacta cgattatgtt
     2461 tatcgctctc tatcattact tcatgaacac catatacatc tcttgccata tcatcaatta
     2521 taggaaattt attgtagaca gattttacaa gccatccttc ttcactttct atttcaaata
     2581 atgcatcagt tgcatgagct tcatttcctt tgcaaaatgg gcattcttca tcatattcat
     2641 tagtttcttc atcttcattt gggatatctg ctgtatctaa aggtcttttt aacctatctg
     2701 tagcaaatat aacaacatca ttggtaattg gatctattct taattctttc ataattaaca
     2761 cctcttagtt aatagccttt aatataatta tatgatattt atcgtatctg ttaaataaat
     2821 ttataatatt ttttataatt ttgcatattt attattatat attttgtcta tagctgaaag
     2881 attataacta aaaaatcact atcagtatat cagaatatta tcttactata aattaattta
     2941 tgaatacata atttagtggc ataaacatgg gtattttact ataatttgtt aaaagtttat
     3001 tttaaagcta tattaatttt ttttgatgat ttttacccat aagtatgtta ttattatctt
     3061 gtaaagatgt cttgtattca aacatacaat ttacataata caatatacgt atttaaatta
     3121 aatagggggt attaaaatga attattcaaa cagagttagt gcaatgcaag cctctccaat
     3181 cagaaaactt gttccatttg cacaagcagc aaaagataaa ggaatcaaag tatatcactt
     3241 aaacatagga caaccagaca taaaaactcc taaaggattt tttgatgctg ttaaaaactt
     3301 tgatagcgaa gtcttagaat atgctacatc agaaggtatt ccagaattat tagaagcact
     3361 tcaaaattac tataaaactt acgatatgaa ttttgaaaaa gatgaattat tagtaactaa
     3421 tggtggtagt gaagctttac ttttcactat gatggcagtt tgtgacccag gagataatct
     3481 attagttcca gaaccattct atacaaacta caatggattt ggtcaatctg taaacgtaga
     3541 agttaatgct gttacaacaa aggcagaaaa cggtttccac cttccatcta aagaagaaat
     3601 attgtctaaa gtagatgata aaactaaggc tataattctt tctaacccag gaaatccaac
     3661 tggtgcaatt tatacaaaag aagaacttaa tatcctagct gaaatagcta aagaaaaaga
     3721 tttatggata atagcagatg aagtttatag agaatttgtt tatgatgggc ttgagtatac
     3781 aagctgtggt aacttagagg gtgtacagga tagagttata ataatagaca gtgtttctaa
     3841 gagatacagt gcttgtggtg ctagaattgg ttctatcgct tgcaaaaata aaggtcttat
     3901 cgctcaaatc cttaaattat gtcaaggaag actttgtgtt cctacattag agcaaatagg
     3961 agctgttgag ttatacaaaa ctcctgtttc ttacttcaaa gaagttaatg aagagtacaa
     4021 aaaaagaaga gatgtattat acaatgaatt aatgaaggtt gaaggtgtta tatgtaaaaa
     4081 accaactggt gctttctata tagttgctaa attaccagtt gaaaatgcag aagatttcac
     4141 aatttggatg ttaaaagaat ttaacaaaga taatgaaaca gttatggttt gccctgctga
     4201 aggattctat gctactccag gtttaggacg tgatgaaata agattagctt acatcttaaa
     4261 tgaaaaagac cttcatagag ctgctacatt attaaaagaa ggtttagagc aatatgtagc
     4321 tttacaaaaa taatttttta aacttaattt atataaattt aatgatataa aatgtcccct
     4381 tttcagatat tatttgaaaa ggggacattt cttaattaat atattaatta agacttagac
     4441 ctgactattt ttcattttct ttatatagtg ttggccagta atctttattc actttaatta
     4501 aagcatctaa aacttgtctt gccttagttg gagagattat agttctattt aatgttaaag
     4561 ataaaatagc tttttcataa gattgttcaa agtatgcatc aactgctaac ttttcataag
     4621 ctagttgacc ttctaacagt cccttataaa atgttggtat attacctaca tgtaaaggtc
     4681 tcggtccatt ctttgtaaga atcgcagcta cttctaccat tgcatcatca ggtaagttgc
     4741 taatagcccc attattttct gttataacta tggctatttg gtgtttgtta tgagctattg
     4801 cttctgcaac ttcaactata aattccccat gagcatcatt atgcactaaa ttagaaccta
     4861 tagatgttcc tttttctata acagatttac attcttcaaa tacacgcttt tctcttccat
     4921 tcataacttc tcttgctcta gtacaattta tatttgattt agctactttt ttatcaggat
     4981 atagataata ctgtacatat gtattaggta agtaatctgg tacatcttcc aacatatctt
     5041 taaccattcc ataagtgtct aaccaagatt tatctctttg ttctgcatca acaggttgga
     5101 atccagagtt tgctactaaa tcttttatct taggtaccaa atcttcacca tttttatcat
     5161 acaaatgtgt aaaccatcca aagtgattta atccaaagta tacaggctca aatgttcttg
     5221 aatccatgtc taacaatctt ccataagacc ttaacaagtt aactggttgg tcacacatat
     5281 taagtaatct tttatcatct ggaaatactc tttttaatgc ttctgcaaca atagcagcag
     5341 gatttgtata atttaatatc catgctttag gagagtattt tcttacagtc ttaaccattt
     5401 ctatcatatc acctatagac cttaacccat aagcaaatcc accagctcca caagtttctt
     5461 gaccaaccag tccaaattgt agaggaatct tttcatctaa ttctcgcatc ttaagaccac
     5521 cagttctcat ttgaacaaat acaaaatcta catctataaa tgcttcatct gggtttgtag
     5581 tatattcaag tgttgcttta ggatattctt ctttaaataa tatttttcca aattccccta
     5641 ttaatctttg acgttcttct actacatcta acatagttac tttatttaga ggaaatctat
     5701 cactcatttt acataaagac tttaaaagtc ctggagtcca agtactgcct cctccaacta
     5761 tagctatatt gtatcttttt ttcattgtca tattaatcac ccctgttttt tattaactaa
     5821 cttgtaagat gattataata tataaagttt tctacatgaa tacttttagg taatcattaa
     5881 aaatagttca attttagtat ttttttcaaa attgtaattt ttttcatcta ttgtattttt
     5941 caatgtattt atgaaacata tattccataa gagaaagtgc tggcactcta gatgtatagt
     6001 taacactatt aaaattatat tgtggagaag atacaaataa ttttatatca gctatatttg
     6061 ataatgaatt gacacttata tttgtcagag aaattacttt aacttgattt gtttttgcta
     6121 tattacatgc cttaataact tgagcagtct ctccagacat agatacagca attacaaggt
     6181 catctttagt aatatttgat gcagccaaat acatgagagt tgaatcatca tagtatttta
     6241 catttacacc tatagctgaa aaacgttgag acatttcagt acatactaat ctagaagacc
     6301 caacaccaaa aaaatatata tgcttagaat tatgtatttc atttaaacac atatctatat
     6361 tctctacatt tattaaattt tgtgtatcca taacatcagt aaaaatatca ctttgacttt
     6421 tagtaaactc cttatttctt tcatttctat ttgaatatga aaaaactaaa aagtttttaa
     6481 attcactata tccagaaaag ccgagcttct gacaaaacct tactatgtat gcagtcgaat
     6541 taaaagtttc atttgctata tctttaatct ttttttgatt tattttttca gaatttttta
     6601 gaaaatagtt taaaagagat atttcatttg tagataattt tttttgattt atatctaatt
     6661 tgtctattag gttcatttat acctccataa taatgatttg tagttaaaca actttctcat
     6721 atttattata taaatataca ctatacagca tttatcttat gtttattata ctataaaaaa
     6781 gacaatacaa attataaatt agtattgcct tttaatattt actttaaata gacattgcaa
     6841 aagaaacttc gtctcttact tgagatacag atggcccata aattatttgg atatctttat
     6901 cagatacttt tataactccc attgcacctg tatatttttt aaaagcattt tcatctactt
     6961 tactcatatc tttaactact actcttaagc gagttataca gtttgttata tcttctatat
     7021 tgtccttacc acctaaatat ttaattatag ataatgctct cttagtagtt tctccacttt
     7081 gagctatttc tactttattt gataaaggtt ttaaatcaaa atttatatct gttatttctt
     7141 ctcgtcctgg agtttgtaag ttaaatctaa gtatcaaaat cttaaataca ttataataaa
     7201 ctattgcata cactaaacca agtattatag aataaatcca ctttgtattt ggttgcataa
     7261 ctccaaatac tactaaatct attatgccac cttgagtatt tcctattgct actccaaata
     7321 tatgcatcat cataaatgat atacctgata aaaatgcatg tataacaaat aatattggtg
     7381 atacaaataa gaatgaaaat tccaatggtt ccgtaattcc tgttacaaat gttgctaaag
     7441 caccagctag taatatacct ttaaccttcg acctattttc aggctttgca gttttataca
     7501 tggcatatgc agcagcagga agaccaaata ccattatagg tattttccct tgagctaaaa
     7561 atctagttgc ttctgttgaa aaactgattg tttcagggtc acttagttga gctaagaata
     7621 tgttcaatgc tccaaatact tcttgccctc ccacaactaa agaacctcct acttcagtaa
     7681 atctaaacat agcatttaat atatgatgta atccaaatgg tattaaaagt ctttcaagaa
     7741 atccaaatac aaatgttcct aaatatccta aactagctat accaatacct acactctgaa
     7801 taattgtatt tacatatggc catatatatg gtattattat ccccaaaata gagaatacta
     7861 ctgttgttat tattggaaca aacctagttc caccaaagaa tcctaaataa tctggcagtt
     7921 ttatattata gtatttatta tgtaatgatg ctgttattat accaactaca attccaccaa
     7981 atactcctaa ttctaatgtt tgtatgccta aagttacagc ttgacccatt tctctcatca
     8041 tgtcaggttc agcaagaatc cccctacacc ctaacatata atttacacta gtgtgtaata
     8101 ctaaataacc aacaaaacca gaaaatgcag aaactgcttt ttcttcttta gcaagaccaa
     8161 cagatattga tatagcaaag aatattgcta agtttccaaa aagtactcct gttatagctt
     8221 ttgtaaaacc caatattcct tgaataaaat tatttgctaa aaaaggcata tcactaacta
     8281 tattaggatt tgaaaatgct gaacttattc ctaaaaatat acctgctgca gatattaatg
     8341 ctattggcaa taaaaatgat tttcctaact gtaaaaagaa ccctttcatt ttttgtttca
     8401 tttctatccc tccattttta aatttttaaa acgttttcta tgtcataatt atatattttt
     8461 attttgtttt tgaaacttta taatttgttt taaaatattt ttacataaat agtaattttt
     8521 tcaaaactgt aaattttttc aaacaaagac atagtaacgt tgtaacatat ataaatttaa
     8581 aaagagctta gaaaataaaa ttattgaata taaaatggaa aaatataaat tacacaaaga
     8641 gatatgagta cgtactaaca aatacgaaaa tgtataagaa attataaaaa agtacatcaa
     8701 gaaaatttaa gatgtacttt ttagattgta tttagactta taattatata gttaaatgaa
     8761 taacaaagaa ttaatcttag tactattaaa tacaaaaatt tttatatttt ttctatctaa
     8821 attcttcttt gtttaatata tattgaagag tatttattgc ttctaaatat ttttttctgt
     8881 cttcttcagt taatttagaa agtttttctc ctaaaccatc acttaattta tccataaaat
     8941 cagttgctat cttatctccc tcttcagtaa tgtcaattag atattttctt ctatcaacta
     9001 aatctctttt ccttgttaca tacttcttat cagttaaatc atcaaccata ctagttaaac
     9061 tgcctttttc tatatttaac ttagagcata aatcagtcat acttattact ccataatttt
     9121 ttatgaaaac taatgctctt aattgtgttt tatttacatt ataatctggt gcaaattttt
     9181 ttaggtcttc taagtacagg ctagaataaa tcttaggaaa tgtttttact aaaaaactta
     9241 tggtatcttt tactatatag ttcatataat cacctcggtt gttttaaaat ttattaaatt
     9301 atctaaataa ctttatttca gtttacatta aaaatattgc aagtacaata gtttttgctg
     9361 aatgtttaaa tttaattagt aatcttatca tttttttatt tttatttata ttattcctat
     9421 taaatattat ttatatagct attttattaa attcatggta tagtaagtaa agaagaactc
     9481 ttcacagcgg tggagagaag acgctagccc attaaaatgg ctatcttatt tataaataag
     9541 atagccgttt ttaattatat tttatctgta caattctata ctcttaggtc tacatctact
     9601 tttcctaagt cttccttata atcttttata gcaggttcta caacttcatt tacaaattct
     9661 acaacttgtt ctggagctct acctataaag ttttttgggt ccattataga tagtatttct
     9721 tccttgctca ttttaaatga atcatcattc attataagtt caattaagtt attatccttg
     9781 ccttcatgct ttactctata ggcagctttc atagaatatt ctcttattat ttcatgcaat
     9841 tcctgtctat ctccacctct ttttacagct tccataagta ttgtttctgt agccataaaa
     9901 ggaagttctt catttacacg tctatttatc atattttcat atactactaa accatcagtt
     9961 acatttatcc ctatttcaag tatagcatct gctgccataa atgcttgagg tattgccaat
    10021 ctcttattgg ctgagtcatc taatgttctc tctaaccatt gagtggcttg taccattgca
    10081 gggcttatag attcagagat tatatactta gataaagatg ctattctctc acttctcatt
    10141 ggattcctct tataagccat tgctgatgaa cctatttgat ttttttcaaa tggctcttct
    10201 aattctttta aactttgtaa aagtcttata tcattagtca tcttatgcat actttgagct
    10261 atccctgata gtatgcttat tacttgataa tctaactttc tagtatatgt ctgtccactt
    10321 actgcatagg aagaatggta tcccatcttt ttacaaattt tcttatctaa ctcttttact
    10381 ttttcgtggt ctccttcaaa taagcttaaa aaacttgctt gagtaccagt agtaccttta
    10441 actcctctta acttcatgtt gtctattcta tagtttaaat cttccaaatc aagaattaaa
    10501 tcttgagccc ataaacaagc tctttttcct actgttgtaa gttgagcagc ttggaagtgt
    10561 gtaaatccaa gagctggcat atctttgtac ttaagtgcaa attcttttaa attgtttatt
    10621 aaatttacaa gctttactct tagaagtttt aaagcttcat tcatttgtat aacatctgta
    10681 ttatctccaa catatgcaga tgttgctcct aaatgtatta ttcctttggc tttttcacat
    10741 tgtaaaccat aagcttttac gtgagacatt acatcatgtc ttacttcttt ttctattttt
    10801 ctagcttcat caaaatttat attatctata ttagctctta gctcatctaa ttgttcttca
    10861 gttatattga ttcctaactc atgttcacct tctgcaagtg caacccataa ccttctccat
    10921 gtagagaatt taaattgtgg agaaaatata taactcatgt ccttgctaca atatctgtct
    10981 gtaagtgggt ttgagtaagt agtatattta ttatctatca ttatattagc accttcctta
    11041 aatcttttgt cgtgtgatta ctgtgtacac attagtacat aaataattat atataatttt
    11101 acgaactata acaagacttt tttatttttt gttcacattt atatatagta ttttttattt
    11161 attactattt tttatttata tccaaattat ctttttcaat taagtaatcc actatttcac
    11221 tatcaacaaa atttaataca tacttatatc taattgcata gtatttatca ctccatccaa
    11281 gctgattttt tacatcactt tcatctgccc caagccttaa acttattgct gcaaatgaat
    11341 gtctaaaatc tcttgctgaa tattgagaaa gtccagctaa atctaatgct tttttgacta
    11401 taagtctgac atttctatct gttatagaat tactcttttg agttgtaaaa ataaaatcat
    11461 cactaggtat tattacctct ggaagcccag aataattcct gtaatcttct aaaagtttaa
    11521 aaaagtatgg atgtaattta actactcttt cttttcttcc cttacctaac cttacatatg
    11581 agttatcgtt ttcatctacc ataaggtctt tccactttaa gctaactaat tcatttaata
    11641 aacacccagt agtaactaga cagactatta ttactctatc tcttatattt aattttggta
    11701 ggatacctat aagtttattt atttcttgta tacttagaac atcatctttt gtttttattc
    11761 ttgttactgt gggtttttct acatatctaa atggatttat atctatatat ccttcttttt
    11821 ttaagaagtt ataaaaacta tgtaaataac tatatatctt ttcacaagtt gatttcgcat
    11881 atttagtctg tatatagtct acaaaatttt tacaatcttc tttcgtagca taaatcaatt
    11941 ctttcccttt taaaaattct ttaaacaata taacctttga taaataatcg tgtttcgtgt
    12001 ttggatttaa ttttgtagaa aaaacattaa aagtttcata ctcataatca tctagtattt
    12061 ttgtactata cataataact cctttccttt tcataaaata aaatagctat acttttacta
    12121 taccatatat ttccccctca aatatacccc ttattcaata gataactttt aagtttattt
    12181 tgttatatta tgaaggtttt atgaaaatat caatcttcca ttgtgcacta cacagtacta
    12241 tggtattata agttagtaaa aggtggcatt tttttattaa tctatgaata aaatatgcta
    12301 ctataaattt gtattggagg tattttgatt tggaaacatt tagtttgctt gaaattttta
    12361 aggcagtcat tttgggcata gttcagggaa taacagaatg gctaccagta agtagtacag
    12421 ggcatatgat attagttgat gagtttataa aattgaattt ttcaaataca tttataagta
    12481 catttttagt tgtaattcaa tttggttcaa tattagctgt acttgttata ttttttagaa
    12541 aattaaatcc ttttgatagc gcaaagaata ttaagcagaa aaaagaaaca gtccgtttat
    12601 ggcttaaggt tataattgca gttataccat ctggagttat tggaatactg tttgaagatg
    12661 atatagatag attattcttt aattcaacag tagttgctat tgctcttatt gtatatggta
    12721 taataatgat agggcttgaa aagagaaata aaaaacctaa gtataaagat ttttctcaag
    12781 ttacatataa attagctctt tgtataggat tattccagtg tctagctctt ataccaggta
    12841 catctaggtc tggttctact ataataggtg cagtattact tggtacttct agatatgtag
    12901 cagcagagtt ttcattcttc ttagccatcc ctacaatgct tggagccagt gcattaaaac
    12961 ttctaaaagc tggatttgga tttactggat ttgaatggct tattttaggt gttggttctg
    13021 tagtagcatt tgttgtttca attgtagtta ttaaattttt tatggactat atcaaaaaac
    13081 atgacttcaa agtatttggt tattatagaa tagtcttggg tatagtggtt cttgcttatt
    13141 tctttctatt ataatgtatt ctaatttaat aacaaatgat aaggagaaaa gttatgagtg
    13201 ttaaaaaaga aatatttgat tggattaagt caatagctat ggctattgta cttgcatttg
    13261 taattctaca atttataaga ccttctattg taagtggaga atcaatgtat cctactttag
    13321 atgataaaga ttatctgatt ttaaatagga tatcatacaa ggttggtaaa cctgaaaaag
    13381 gcgatattgt agtttttaaa accaatttag ttgatggaga aacaggaaag aaaaaagact
    13441 taataaaaag agttatagct actgaaggtg acagaataaa aatatcaaat tctaaagtgt
    13501 atgtaaatgg aaaattatta aatgaaccat atatacacaa taactatact tctggagata
    13561 tagatactgt tgttccaaaa ggtaaactat ttgcaatggg agataataga gaaaatagta
    13621 atgatagtag attccctgat gtaggtatgg ttgatgaaaa tgaagttctt ggtaaggtta
    13681 tggtgagact attacctctt gataatattg ggaaagtaga ctaaaaaata agagactgaa
    13741 ttggtaaagt ttattttaca aatctcagtc tctttttatt ttcttaaatt acaaatattt
    13801 ttttactaaa tatcttttga ttctgtaata agtcttatta tatcacttgc ttcttcatta
    13861 aaagttgtta ctatacttag gtagtctgtt gctctactca tagctaaata aaccttattt
    13921 aaatctccta caaagtcatt tacttgataa tcttgttcaa tatcatttat agtttgatta
    13981 tataacatct ctaattcaca tactattacc gctttatact ctaaattctt tattgcatat
    14041 atatttgcta ttgtagttcc taccttctta cttatatttg tcaaattatc ttctgcacat
    14101 atataaggaa tttttgcctc ttccaatgct ttttttaaca tatattgaaa gtaaatggtt
    14161 tttccacttt ttaatttctt cttattgtaa ggataaacga tagcaacttc agaataatca
    14221 agaccttttt tacttattaa atactcaatt tcccagatta cagaacttat ttggtcatca
    14281 aggtcactta cttttattat atcaacagac ttatttccac ctctaagtgc tttagtataa
    14341 aagaaagtac taaattctgt atttggtctt aattcgttga tatatgagtt agaattattt
    14401 gaaaatttat ttgtaaaatc tacaatctct ttagcttgtc tataattttt acttaagata
    14461 atcttatcat caaattctat accattatat aattttttaa atatattcaa tctattagag
    14521 atattcaagg agttacaaga acatacatta aatatgaatt ttgttttata taaaaactcc
    14581 cttataaaat ctatttcata ctctaaaaag ctttctgctt catcaataaa aatagccttg
    14641 aacatatttt tattttttat aatgttctgt gcttgtttta caagattatt aaaggtcttt
    14701 tcgtaatcat tttttaacat attataatct acaattaaat tgaatttttt agctagttta
    14761 aatataaaag aactaaatgt gtgaacttct aaattgttat tatctttgta taataactct
    14821 atcctttctc gaagctcatt gcacaattgt tttgtatgtg taaatatgac taatttatga
    14881 tgtggatata cttttgctaa ttttatagcc ctagaaagca taattgctgt tttgcctata
    14941 ccagaaccac cttcaataag tgtattccca tatttaatag aaacaacatc tttaatttga
    15001 acgtcttcca tcatagttgc tgtatactta tagtcatcat tgtagaatga aattttttta
    15061 aatttttcat ttagatgaag tttatcattt attatatagt attctgaaca tatgtctagt
    15121 aaaaataaat ttaagtttat ttcatcattc tcatcattaa gatattcctc cagcgaaccc
    15181 ttattcatta tatcttgaag cttattttta tctattatat tattattaac aaattcttca
    15241 aattcatatg tttcctcaac ttcaacgtat ggcataatgt aaacgtagtt ataacttata
    15301 tttctattct tttgtcccat ttttagtttc aaaagttcat attcctcatt cataacttca
    15361 agtaactctt cttctaaaat aaaaaatata tcttctgttg tatccataaa ttttataaat
    15421 aaaactcttc catctttaac atacaacaaa tcggtattta ttcctttaaa aggagtaact
    15481 tttggcacta ctttaacgtc ctcattgata ttttcgtaaa atattttctc gaactccttc
    15541 aattttaggg cgtctaactg agaatttata tttatgtatt ggctcactta cattacctcc
    15601 ttctgttata cttaattata ccattttgaa ctatattttt atatatactt tttataggca
    15661 aatttagtaa ataaattcaa aataaataca aataaataca aaactgctaa aataattttg
    15721 caataaatat agatatttat tgttatagaa tactttctgt aaataata
//
LOCUS       DAEPUT010000094        15677 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.096, whole genome shotgun sequence.
ACCESSION   DAEPUT010000094 DAEPUT010000000
VERSION     DAEPUT010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15677
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.096"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            51..869
                     /gene="larE"
                     /locus_tag="KRL22_003204"
     CDS             51..869
                     /gene="larE"
                     /locus_tag="KRL22_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HBH1273649.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            924..2072
                     /locus_tag="KRL22_003205"
     CDS             924..2072
                     /locus_tag="KRL22_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBH1273650.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            2208..3596
                     /locus_tag="KRL22_003206"
     CDS             2208..3596
                     /locus_tag="KRL22_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1273651.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            3625..4323
                     /locus_tag="KRL22_003207"
     CDS             3625..4323
                     /locus_tag="KRL22_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1273652.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            4326..5759
                     /locus_tag="KRL22_003208"
     CDS             4326..5759
                     /locus_tag="KRL22_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1273653.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            5781..6518
                     /gene="truA"
                     /locus_tag="KRL22_003209"
     CDS             5781..6518
                     /gene="truA"
                     /locus_tag="KRL22_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH1273654.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHSPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    6629..6836
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7089..8288
                     /locus_tag="KRL22_003210"
     CDS             7089..8288
                     /locus_tag="KRL22_003210"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBH1273655.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            8535..9581
                     /locus_tag="KRL22_003211"
     CDS             8535..9581
                     /locus_tag="KRL22_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HBH1273656.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            9689..10852
                     /locus_tag="KRL22_003212"
     CDS             9689..10852
                     /locus_tag="KRL22_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1273657.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNPSSTDLQEIAKAITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKIYLRDRKPKINTLYEKLVEDLSRDCSSREVQSVVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASRFIGEAFKIYFDNNNC"
     gene            complement(10941..11321)
                     /locus_tag="KRL22_003213"
     CDS             complement(10941..11321)
                     /locus_tag="KRL22_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HBH1273658.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(11324..11983)
                     /locus_tag="KRL22_003214"
     CDS             complement(11324..11983)
                     /locus_tag="KRL22_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBH1273659.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(12089..13063)
                     /locus_tag="KRL22_003215"
     CDS             complement(12089..13063)
                     /locus_tag="KRL22_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH1273660.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(13103..13450)
                     /locus_tag="KRL22_003216"
     CDS             complement(13103..13450)
                     /locus_tag="KRL22_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273661.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(13668..14624)
                     /locus_tag="KRL22_003217"
     CDS             complement(13668..14624)
                     /locus_tag="KRL22_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBH1273662.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPIRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            15067..15435
                     /locus_tag="KRL22_003218"
     CDS             15067..15435
                     /locus_tag="KRL22_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HBH1273663.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT         6168 a         1669 c         2548 g         5292 t
ORIGIN      
        1 aagaatgtaa aaaaataata tatagtttta tagttcatat ttttccagat atggaggtaa
       61 attttgtgaa ggaaaaagaa aaattagata aattaaaaaa aatgttactt gaattaggca
      121 gtgttgtagt tgcttattct ggtggagtag atagtaattt tttgcttaag gtcgcaaaag
      181 atacattagg tgaaaatgtt atagctgtga ctattcatgc aatgatgcat tcaagtaggg
      241 aaattgaaga ggctaaacaa tatactcaaa attttggtgt taaacatatc atattaaata
      301 tagaaaactt tgatttaaaa gaatttaaag aaaatggtgt tgatagatgt tatcattgta
      361 aaaaatatat attctctaaa ataaaagagg tagcaaaaga acataatata aagtacatag
      421 tagatggaac aaatatagat gatttaggag actatagacc tgggcttaag gcattgagtg
      481 aattaggagt aattagtcca ttaaaagata gtagtttaaa aaaagaagaa attaggtcgc
      541 tttcaaaaac attaggatta aatactttta ataaaccatc atttgcatgt cttgcgagta
      601 ggatacctta tggagttgaa ataacagatg aaaatttaag aatagtagaa aagagtgaag
      661 aatatctatc caatttaggt ttttctcaat ttagagtgag aatgcatgga gatatagcta
      721 gaatagaagt tggacaggaa gaactaggta aattttttga aaataacaat tttaataaag
      781 ttgatactaa attaaaaata tttggcttta aatatgttac actagatatg tcaggatata
      841 aaatgggaag tatgaattta aatgtgtaga ttattttaaa aataaataag ttttatagtt
      901 aatataagga aacaggaggt tttatgaaaa attatacgtt aatatcgcca tgtttttttg
      961 gaatggaaaa aatgctggct agagagatta ctaatttagg atatgaaata ataaaaacag
     1021 aagatggaag aataacatat aaaactgatg agtttggaat agcaaagtca aacatgtggt
     1081 tgagatgtgc tgaaagagta catcttaaaa ttgctgaatt tgaggcaaaa agctttgatg
     1141 aattatttga aaatacaaaa agaataaact ggtctagata tataccttat ggagctcaat
     1201 ttcctatatc aaaagcttcc tctataaaat caaaattata cagtacacca gatgtacaag
     1261 ccatagtaaa aaaggctata gtagaaagct taaagaaaag ttatttggag gatggtttgc
     1321 ttaaagaaga taaggagaaa taccctattt ttgtatttat acacaaagat aaagtaacca
     1381 tttctataga tacaacagga gatgctttgc ataagagagg atatagagaa aaggcaaata
     1441 aagctccaat aagagagact ttagctgctg gtcttattta tttaactccc tggaaagcag
     1501 gtagagtttt agtagaccct atgtgtggtt ctggtactat attgattgaa gctgctatga
     1561 ttggtataaa tatggcacct ggcttaaata gagagtttat atcagaaaag tggagaactc
     1621 ttgataagaa aatatggtgg gatgtaagaa aagatgcttt taataagata gataatgaat
     1681 ctaaatttaa gatttatgga tatgatatag atgaagaatc tatagatata gctagagaaa
     1741 atgctgaaat agcaggtgta gatgaatata tagagtttaa tgtaggagat gcaactcaat
     1801 ttaaaagtga agatgagttt ggatttataa tcactaatcc tccttacgga gaaagattag
     1861 aagataaaga cagtgttaaa cagttgtata aggagcttgg ttatgcattt agaaaattaa
     1921 aaaattggtc gtattatttg ataacttctt atgaagactt tgaatatgag tttgggcaaa
     1981 aagcagataa aaaaagaaaa ttgtataatg gtatgttaaa aactaacttt ttccaatatc
     2041 cgggtcctaa gcctcctaga aataataaat aagttttaca tgatttattt gtaaaatata
     2101 aaattttatt aaaataagta aaacattatg atgccttgaa acgtctaatt attgtgagga
     2161 gatttttgtg aacaaattta aagatttata ggattaggag gagttaaatg aaagtgttaa
     2221 agcttattac tgtagtagcc ctgatgatgt tatttgttac tggatgtaat ataaaaactg
     2281 aatctccaga acaattagcg aagatacctg actatgatga tacaaaaaaa gtattgtatg
     2341 atggtattga ccagttacta aaaccagatt catctatgat attgccttct aatacaaaag
     2401 aagtaggaaa aataaataag gtagatttaa acagcgatgg aattgatgaa ttagtagtat
     2461 ttgaacaaaa agaagattta agtaataatg tgagtcaggt agggtttgta accttgagtt
     2521 acaatggaga aaaatacgta cttggagacc attttttaga aaatggcgaa tcaatagaat
     2581 atgctaattt ttatgatttg gactcagatg gatataagga agttatctta ttggttaaat
     2641 ccaaagacaa aacgaatatg catatatata aagtagtaga taatgaaata acaaaaatat
     2701 atgacttgga tgcatcatgg cttcaaaata aagaagattt taatgacatg aaagtaaaaa
     2761 ttggatatat agatggagat gacaagttag acatattgat gcttcatttg aataataaga
     2821 ctaatgaaat gtttgcaagt gttgcaaatt ttgatgggaa aatgaaaatc aaagattctg
     2881 ttaagtttga aaatgtaaaa aacttaagtg aattatatat aacattaggt aatgttgctt
     2941 catctgttgg aaattcttct gcagctataa aaggtattgt acttgatatt cctatattga
     3001 aagataataa ctatattacg cagatacttt atatgaaaga tgggaaaatt aacaaagctt
     3061 ttagtgatta tgataaaact attactaaat cttattatat acctgtagat gatattgaca
     3121 aagataagat tatagaaata cctatagttg caggcagtac aggtaataat aaaaatactt
     3181 atagttctaa atcatctgca actataagtt ggtatagatg gaatggaaaa gaaggtgctg
     3241 actcaagttt aatatttaca agtcagatat attataatta taaatataat tttaaattat
     3301 ttattccaaa taatttattt gataaaatac ttgttgaaca ggaatttgtt ggagaaaaag
     3361 cagtatttaa attttactat tttgactatt cagaccgtaa gaatttattt aatatagtag
     3421 tagagagtaa aaataaactt gaagatagaa aaaatacagg tactcaaaat tctattgtac
     3481 ttcaagagag cgatgaatat actttcttac tagttgtaaa caatgcaaat gaaatggata
     3541 agctagatat gactatagac gcattaaaag aatatttctc attaatatat ggttaatatt
     3601 atactcaatt ggaggtttta ttttatgaag gaaaagatac ttatactaga agatgaaatt
     3661 ggtattagaa gttttgttag tataaactta aaaagggaag gctatgaaat agttgaggca
     3721 ggtactggaa gagaagctat agaaaaaatg acaacagaaa aggatattac aatagctctt
     3781 ttagatgtaa tgcttccaga tataagtggt atagaagtat gtaaatttat aagggagaat
     3841 tttgaccaag taggtataat aatgcttact gctaaagctc aagaagatga taaaatagaa
     3901 ggatttatct caggagcaga tgattacatc ataaaaccat ttagtataaa agagctttta
     3961 gtcagagttt ctgctcttct tagaagagta gcaaaggatg attcaagtgt taagtcgagt
     4021 gagatagttt ctccaccatt tatacttgat atagacaaaa gaaaattatt taaaaatgga
     4081 aaggaaattg agcttacacc aactgaattt tcaatagtga aatatctaat atcaaatgct
     4141 aagcagtcgt taagtagaga ccagatatta gacgaagtat ggggaactaa ctatttatat
     4201 gattttaaaa tagtagatgt aaatataaga aggataagaa ataaaataga agatgaccca
     4261 tcaaaaccaa aatatataca aactatttgg ggttatggat actgttttag aaaggaagaa
     4321 taatagtgtt acattttgaa ggtctgagaa aaaaagtaat aaaaaactat tttataataa
     4381 ttattataat ggttactctg tttgaaggat tgttcatgtt ttacatacaa aactactatt
     4441 atgattctgt caaacagcta cttgaatctg aaataaaata tgctgatgaa tataatgcta
     4501 ttacaatgga aactacaagt tttgagaaaa aagtaaaaaa tatatttgat aaacaaccct
     4561 taactaaaaa ttcagaattt ggaatttcaa taatagataa agataaaaat attatattag
     4621 accaatatgg ttttaaaagt aaagaaaaag caaactatga agatgttaac aatgcattaa
     4681 aagatataaa aactaaaaat ttaacacctt atacttatag aataccagat acaggggagc
     4741 atgttatgag tatctcctta ccacttaagg taaataatat aatagaaggt gttgttagat
     4801 atacagtatc attagatgct attgataatg caatattaaa gcaagctaca tggcttatat
     4861 tagcaggaat atttatactt attatagcta tactaataag tcttaaattt gctgagactc
     4921 ttataaaacc attacgagag ctaaagaaat ttgcaaatga attggctgta ggaaattata
     4981 atataaaatt agaaaagatg aagattgtag atgatgaaat tggtgattta gcacagacat
     5041 ttgaacacat ggcacatgag attgacaaaa gtgaaaaatt aaaagaggaa tttatatcat
     5101 ctgtatctca tgaactaagg actcctctta catctataaa ggggtggagt gaaaccttag
     5161 gttatgaaag tataacaaga gaagaactag acttaggttt aggcattata caagatgaaa
     5221 cagaaagact tataaaacta gttgaagaat tattagactt ttcaaggctt tcttcagaca
     5281 ggataaaact tcatgttgat atagttgatg ttgaaggttt aattgtaggt gttgtaaatc
     5341 aacttaaagt taaagcagct gaaaaagata tatcactttt atttgaattt gaaaatgaat
     5401 ttatagagaa cattcaagga gataaaaata gattaagaca ggttctcata aatttaatac
     5461 aaaattcatt taaatttacg agtcaaggtg gttacataaa agttgtagct tctcaagatg
     5521 aagagataac aaccatatca gtagaggata atggttcagg tatagaaaag caaaatttaa
     5581 ataaagtgtt agataaattt ttccaagaag attataataa ggctggtagt ggattaggac
     5641 tagcaattag taatgaaatt gtaaaacttc atggtggaag aatgaaaata gaaagtgaaa
     5701 agaatgttgg aacaaaaata acttttaata taaaaaataa atttgctaaa caagcataaa
     5761 ttcttagaaa gaggattaag atgagaaaca taaaaatgat agtagcatac gatggttcaa
     5821 gatataaagg atatcaaaaa ttaggtgaca ataatatgac tattcaagaa aaacttgaaa
     5881 atgttttaag taaaatgact aatgaaacag tggagataat aggttctgga agaactgata
     5941 tgggagctca tgcaagagga caagtggtaa attttagaac taattgtatg gattctttgg
     6001 ataaaattca aaaatattta tatgaatatt taccagaaga tatagttgta aaaactgttg
     6061 aagaagttga tgaaagattt cattcaagat acaatgtaaa atcaaagact tatatgtata
     6121 aaattgacaa taataagtat catagtcctt ttataagaaa atatgctact catgtaagta
     6181 aaaaattaga tttagataga atgagaaaag caagtgagta tttagtagga gaacatgatt
     6241 ttaccagttt tgcttcttct aaatctaaga aaaaatcaaa tgtaagagaa atttattcta
     6301 taaatataaa agaagatgat aatgttatag aaatatatgt agaaggaaat ggatttttgt
     6361 ataacatggt aaggataata gtaggtgctt tgatagatgt tggtctaaaa agaagagctc
     6421 cacaagatat taagtatatg cttgaatcaa aagatagatg tcaatcatca gatactgcac
     6481 cagctaaagg actatgtctt tggaaagtaa catattaatc aattatataa aactctcttt
     6541 aaaataaaaa taaaataaat tatatagttg acataaatgg aaaaataaac tattatatat
     6601 tttataagag agatataaaa ctttatattt aaatcctgtg agaaagagag taacttctat
     6661 gtgttttata gagagctgag gatggtggaa gcttggcaaa taagtattag tgaaaagaac
     6721 tttggaggat actaattgaa tttagtatgt tagtaggtaa tctcgcctta agagaaagag
     6781 tggataagtt tatcttatca attagagtgg taacgcggat atatttcgtc tcttggtttt
     6841 tccaagaggc gttttttaat atatttaatt attagtgttt atctggtatg ttgaacattt
     6901 actaattgat tagctaagtt tatcaataag agtggtaccg cggatatttc gcctcttagt
     6961 attttaaaat actaaggggt ttttttagta ttaaaatgat tttatgtgag tctaaattct
     7021 cagagtcatt caatattaag aatttctata aaataaaaat tataatttaa gattgggagg
     7081 aattaaaaat gaaggaaaaa gtagtattag catattcagg aggacttgac acatcaatca
     7141 taataccttg gttaaaggaa aattatgaag atatagatgt tatagctgtt tgtggaaatg
     7201 taggtcagga agataaaatg gaagatgtat atgaaaaagc tttacaaagt ggagcatcaa
     7261 aggcatatgt ggatgatata agtgaagaat ttgtaactga aactatattt aaagccgtaa
     7321 aagcagaggc taaatatgaa ggaaaatact tattaggaac ttctttagca agacctataa
     7381 tagctaaaaa attagttgaa gttgctcata aagaaggtgc aaaatatata tgccatggat
     7441 gtacaggaaa aggtaatgac caagttagat ttgaagctac aattgcagct cttgacccga
     7501 ctataaaagt tattgcacct tggagaattt gggatataaa atcaagagaa gatgctatag
     7561 actatgctga aaaacataat ataaaggtaa cagcaactaa agctaaaata tattcagtag
     7621 atgctaacct ttggcatgtt tcaacagaag gtggagatat agagcaccta gaaaatgaac
     7681 ataaaaaaga tgtttataaa caatgtgtag acccagaaga tgcatgtgat gtagctgaat
     7741 atgtagaagt ttactttgaa aaaggtgtac ctaaaaaggt aaatggtgaa gaattatctc
     7801 cagttgcact gattcataag ttaaatgagt tgggttgtaa acatggaatt ggtgttatag
     7861 atatagttga gaatagactt gttggtatga aatcaagagg tatatatgag actccaggag
     7921 gaacaatcct ttatgaagca cataatattt tagaaagtgc tactttagac aaagatacat
     7981 tacatttcaa acaaatggta tcttataaat acggagaact tatttacaat ggactatggt
     8041 attgtaaatt aagagaatct atagatgcat ttatggaaca aactcaagat aatgttacag
     8101 gaacagtaaa agttaaactt tacaaaggaa atataaaacc tgctggaata tttactgaaa
     8161 atgctcttta tgatgaagga atatcttctt ttggaaatag tgaactttat gaccacaaag
     8221 atgcagaagg atttattaat ttattcactt taccattaaa aatcagagct atgaaagctg
     8281 gaaaataata aaataaatta tttaagagtg tataaaaact atttttaggt ttttatatgc
     8341 tcttttttta tttgaattta ttaacttata cagtaaatag tataaaaaaa tatattatag
     8401 ttccaaatgg cttaataatg tgaaaatata agacctaaaa tataaatttt ataaatacaa
     8461 tagttattga ctctctcatt gtaagagggt ttatactgaa tctaatgaaa atttatagtg
     8521 aggagataga ttatatgaga aaaataattg aaattaaaca tcattcacat gattatgagt
     8581 gtatgtggaa tggtatagaa gatttatata taaataaaac cggtgaatgc cttccaaacg
     8641 attttttctt tttactgtca ggttttggtt cattttgtta tatgaaaaca aataaagctg
     8701 atttgaaaag aatggtagct ttgggagatg gaaggacaaa acagatgtat aaatttttag
     8761 caccaattgt tggatttgaa tacaaacatc atgagtttaa aaagtatgag caagcattaa
     8821 agaaagcaaa atctgaaatt gatgatggat atccagttat tttaggagct ttagatatgt
     8881 attatctacc atattataag aaactatatc ataaagaaca tattcctttt cattatatat
     8941 taatggtagg atatgatgat gaaggaatat atctgtatga ttgtggtaga acagaattat
     9001 tacatctttc ttatgataaa ttacgtgaaa gcatgaattg caattcccct ggattaagca
     9061 aagaaaatac tatttgcaca ataagaatga atacttcaaa gaataaatat aacattgcta
     9121 gagaagctat tgctataaag cgtgatatgt ttttaaatcc acctaaagga tttttgggat
     9181 ataaaggttt tgaaaagttt attaaagagt taccacagtg gaacactgaa ttggataaag
     9241 atgattatga taagattttg accaatatgg ttatgttttt tggaacagta ccaacaattc
     9301 caaatgcaat caaaggaatt aaagaaccag atactgttca atttaaaggt ggatttgata
     9361 aaatgagtag aatgctcaac agtattgggg aggaatacaa aaacgactct tttatacaag
     9421 tagctgatat ttttgataaa actgctatta taattgagaa aatatccaat attataatag
     9481 attacttaac tcaaacatgt gatgatacag aacaacttcc gttattgttc tctgaggtct
     9541 tagagcatat gaaaacagga tatttaatct tggatgtata aaaaatatat tgttgaccct
     9601 aacattacgt aatagtgtaa tatgaaaata tagcttgaat atattagtag gtattgatgg
     9661 ctgtaaaatt aaaatttgag gtgtggatat gagaacagtg aaacaagttt ctgatttaac
     9721 tggaataagt gtgagggcat tacattatta tgatgaaata ggtcttttaa aaccaaataa
     9781 aattacagat gcaggatata gactttatga tgatgaatct attaaaactc ttcaacaaat
     9841 tttatttttt aaggagattg atattccttt aagagaggtt aaggaaataa tgtcaagcca
     9901 atattttgat aaggttgaag ctctaaaaaa tcaaaaaaaa ttacttattt taaaacgaaa
     9961 gagactggat gaattgatag agcttataaa tcaaactcta agaggagaag gaaatattga
    10021 ttttaaagag tttgatatga gcgagtattt tgatgtttta gaagaattta aaagagagca
    10081 taggaataag gtaattaaaa tttatggtag tgtagaaaaa tacaatgaat atatagaaag
    10141 agttaagtct aatgaagaga aaattgctaa aatggctata aaacaatatg gaactattga
    10201 gaagtttgct aaagctataa aaacaaattt tagcagtgat atattgaatt taggagaaaa
    10261 atttgataga tataaaaatg attgtttaaa agaaaaacat ccaaaattaa aagaattata
    10321 tagaaagctt gtagaagatt taagtaggaa tccttcttca acagaccttc aagaaatagc
    10381 aaaagcgata acagatatat ctaaaaaaga ttatgaaatt ttctctatgg atactggtga
    10441 tgacaactgg tattatatgg ttcaaaatta tctagtaaat cctatgtgga tagaagaagt
    10501 agataaaaag tatggaagtg gagcaggtaa gtttattgga caagtactaa agatttatct
    10561 aagagataga aaaccaaaga taaatacatt gtatgaaaaa cttgtagaag atttgagtag
    10621 agattgttct tcaagggaag ttcaaagcgt tgttgaagaa atagacaatg aaatgaaaag
    10681 aagtaatgaa ttttataaaa tagacaatgg tgaaagatac tttgattata tgtcagagct
    10741 ttatttacaa gattctaact atataaaagt aactgataag aattatggtg atggtgcatc
    10801 taggtttatt ggagaagctt ttaagattta ttttgataat aataattgtt gaaaatttgg
    10861 aagtaaaaaa tatgtaaact ttataaaagc acaaaaataa ggatgtagat tagctccatc
    10921 tatatcctta tttaaagtta ttaaaatata tagtttacat caaacttaac actttcaata
    10981 atatttccca aatatgtttt tatactttca acttcttcta aagattttaa tttattttca
    11041 gtataaattg ctttgtccag aatattaaac cttaatccta tttcatcaaa gtactcatga
    11101 tttaaaactt tgtaccaatg gtttttttct ttattccaac tcgtagatat tgaatcagct
    11161 tctttttgag ctttttccca atcttcattt tctatagatt tttctaaaac agatatattg
    11221 tctttatatc cttctgtaaa atcatatagt ttattgttaa cataaaatcc aaataataca
    11281 aataagatag tccatagtat aacaaatgtt gtagatttca atattaatca ccctttttat
    11341 tttgaataaa tattttatca ttttcatcta aaacacaaat aagaacatct ttaaaagttt
    11401 ctatgtgatt agattttaaa atacccatta accagttagt atctttttga gctatgtcta
    11461 gatttttatt tattattcta ccatccagta taagtgggat aggtaaatga ttaaaagctc
    11521 ttggaggagt actattgtag cttgatgctg gtacaacact tagattacca tcagtctcca
    11581 aaatagcata ttgtacatct tttaggttaa agtatccttg aatcctaagt tgttctaata
    11641 attcatctat actaattctt tcttttttaa gctctttata tacaattttt cctttatcta
    11701 ttaatacaga aggtttacct gataaaaatg aacttaattt tctgcttttt aatgataaga
    11761 atgaaattag agtctgcatg attacaagtc cagatattgc tgcaacacca tttatgattg
    11821 gtatattatt attttccatt gggacagatg caacttctgc aattaatagt gttataacta
    11881 aatcaaaaca gttcatttca gctatttcac cttttcccat gactctaagt gcaattagca
    11941 ctgttatgta taatataata cttcttatta atactactgt catatctatc aattactcct
    12001 ttaaaaaata tttacactta gttagtatat cctatataaa aaatttaatt caaagtataa
    12061 aaaaccttaa ataattggat tcaactattt aaggtttttt tgataatttt aatattaaat
    12121 tttttatgga ttttctgtta cttttattta ttttaataac agattcaaca aaactctttt
    12181 tatctcctaa ttttaagata aaatcaggat attcttcaaa ttcattgagt tttattaatt
    12241 tgaaagaaga agatagattt ttaaagttaa taattttaga gttattcact aatacacttc
    12301 tttttttaaa ataaatttct tttttactta tatttagtat agttaatatt tgtttaagat
    12361 atattattat atcttctgga gttctatcaa atttgagttc aaaattttca tcttcaaagt
    12421 agggaatata atataaaggt gttttgagag caggtaattt attatataat tcttcaagaa
    12481 tatcgatatt tttaggggag ttaaagaaaa agcatttaca tacattcatt aaatccacag
    12541 catctgaaag tgagttatgt ttaatatctc cttctacaga aaaaattttt ttcatattca
    12601 gtaaagatat ttgcttagat aagattctat tattgtatgt aatatgttga gatataaaag
    12661 gttgaatgtc aatcatcata ttaaataact ctaagcattt acctgtatat ttatatactc
    12721 taaatgaagt tagaaggcca gttatatcaa aatcacccca attatatatt gtaacatcat
    12781 caaatttaca aaaccattta taaaaatcat ccataacata taaaagatta ggagcattat
    12841 tgatatctag ttggttcaat ttggttaaat ttttacattt atttgaaagt attttattgt
    12901 attttggctt aactaaagag taataattat ctattgtatt aaattcgtta tcaactaaaa
    12961 ctccaccaat agaaattaat tccgcaccat tatattcttt tggtttattt ttattatcat
    13021 ctagtatatt aaattcaaag tctataaata acttgtattt cataaatcta aagcacatcc
    13081 tcaggtaaat tatttattga gcctaagcat cataagaatc aatagatata atgactctaa
    13141 acatcaaagg ttcattacaa cttttattta tttcataatt taattcaaat aaatctttta
    13201 agatataatt tataagtatt ctttcccaac ccatttttaa attaacttta gagtctatta
    13261 atatattttc tatcttttta aatatttcta tatttgctgg tattatactg agctcaatat
    13321 tacttttaaa cgggttagac tgtaaatctg ttataagtat attttttaat tcctctgtaa
    13381 gttcagaaat taaactatca cctatgtatt tttttatgat ttcctctcta atttctttta
    13441 aatttagcaa tattagtacc tgctacttac atagtagctt ttcctttcct tttaatacta
    13501 ttattcattt ttgaatctta tttagatata ttttaagatt aaaagtcttt agctatataa
    13561 ttttttaccc atttttaact tatattaaca tattacaggc ttatatctcc accctgttta
    13621 cattgaggat ggagtatatt gcctattttg ataaaaatga taggttgcta tttgcctatt
    13681 cctttttctg ataatttttc taacatatct ttggtcattt tatctaaatc ataactaaac
    13741 ttaaagttcc attcttttac tgcactacta ctgtctagag agttaggcca agaatcagct
    13801 atactttgtc ttatagggtc tacatcatac tctatcacaa aatcaggaat atattttttt
    13861 atagaatcag ctatttcttc gggagaaaag ctcatagcag taatattaaa agcatttcta
    13921 tggatgagtt tatcagctgg agcttcgatt aaatccacta ttgattgaag tgcatcaggc
    13981 atatacatca tatccatttt tgtaccttct gctatgtaag atttatatct cttatttttt
    14041 aatgcctcat aatatatatc aactgcataa tctgtagttc ctccaccagg aggcgtaaca
    14101 taagaaataa gacctggaaa tctaacacct ctagtgtcta ctccaaattt tgagtgataa
    14161 taatcacata gtaattctcc agaaacttta gtcacaccat acatagtatt aggtctttgt
    14221 aatgtatctt gaggagtcat attttttgga gaattttcac caaaagcagc aattgaacta
    14281 ggtgtaaaaa atttacaatc caattctttg gctatttcaa gaccatttat taatccattc
    14341 atatttaagt tccaagcttc tagaggttta ctttcagcaa ctgcagaaag taaagatgct
    14401 agatgaatta tagtatctac atcatatttt tttgcaattt caaaaaaacg attcttatct
    14461 gtaacatcta atatctcaaa tataccagat tcacatactg gattaccttc ttttactctc
    14521 cttgaactag cgattacatt ttgttctcca tactcatttc taagctttat tgttaattct
    14581 gaacctattt gtcctaatgc acctgttata agtatttttt tcaattttac aacctcctaa
    14641 gggtttaatt tatgtagtac tacttatttt tattttagca aatcttttgt ttaaatacaa
    14701 agaattaaag ataataatat acgacttaat tgaatgaagt gcagtaagtg cctaaaaatt
    14761 taaagctaat atataatggt atattgtata acaataaaag agtagattaa attattatat
    14821 atagattgtg tgactaagtc acagaaaata gagttaattt aatatataat aaaagcatat
    14881 caagtaaagc tttaaattaa agtaacttta tataaaaagt aatataaatt gataaaatta
    14941 taaatttatt tatagtgaat ataggttgga ttttatagat acaaaaatag tatatatgat
    15001 atgtagacca ttagcatgtt taaagtagca aaacatataa aataaaattt gaaaggaagt
    15061 ataaaaatga caagaccatc aatatatcat agccaaggat acacttgtgc agaggcatta
    15121 ataaagtctt ataatgagga acacaacaca gatataccaa tctcaatagg aagtggtatg
    15181 ggggttggaa tgaatgttgg aagtgtttgt ggagctgtaa atgctgctgt tgttataata
    15241 gggtatttaa atgggcgaaa tagtaattta gatgaaaata tagcaaggaa gtattcaaga
    15301 gagctattga atagagtaag aaataaatac agctcagaaa tatgtgtatc tcttaaaaaa
    15361 aataaagtaa cttgtgaaga aataataaat ttcacatatg atgctctaaa tgatatgcta
    15421 aaaaatcaaa aataattcta agaaacaagt attttacatt cgatagaata cttgtttttt
    15481 tatgatattt ttaataggta ttagtttatt ataattttta aatcaatttt attatatttt
    15541 aattgaaata atctactttg aaaattacta actgacaaaa gaatatgatt atagtataga
    15601 aaaaatgtaa attatttaat attaagtgag agtatatgct tacctatata aaatcgtata
    15661 aattaatggc taaattt
//
LOCUS       DAEPUT010000095        15503 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.097, whole genome shotgun sequence.
ACCESSION   DAEPUT010000095 DAEPUT010000000
VERSION     DAEPUT010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15503
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.097"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            28..879
                     /locus_tag="KRL22_003219"
     CDS             28..879
                     /locus_tag="KRL22_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HBH1273664.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNISNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1012..2625)
                     /gene="ggt"
                     /locus_tag="KRL22_003220"
     CDS             complement(1012..2625)
                     /gene="ggt"
                     /locus_tag="KRL22_003220"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBH1273665.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2850..4787)
                     /locus_tag="KRL22_003221"
     CDS             complement(2850..4787)
                     /locus_tag="KRL22_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273666.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNKIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEVEKINLHIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4774..5541)
                     /locus_tag="KRL22_003222"
     CDS             complement(4774..5541)
                     /locus_tag="KRL22_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273667.1"
                     /translation="MEEILSAENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            5829..6503
                     /locus_tag="KRL22_003223"
     CDS             5829..6503
                     /locus_tag="KRL22_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1273668.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6527..7531
                     /locus_tag="KRL22_003224"
     CDS             6527..7531
                     /locus_tag="KRL22_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1273669.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            7643..8872
                     /locus_tag="KRL22_003225"
     CDS             7643..8872
                     /locus_tag="KRL22_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH1273670.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            8880..9554
                     /locus_tag="KRL22_003226"
     CDS             8880..9554
                     /locus_tag="KRL22_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273671.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            9557..10789
                     /locus_tag="KRL22_003227"
     CDS             9557..10789
                     /locus_tag="KRL22_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273672.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(11075..12340)
                     /locus_tag="KRL22_003228"
     CDS             complement(11075..12340)
                     /locus_tag="KRL22_003228"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBH1273673.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(12393..13541)
                     /locus_tag="KRL22_003229"
     CDS             complement(12393..13541)
                     /locus_tag="KRL22_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH1273674.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQNSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(13641..14186)
                     /locus_tag="KRL22_003230"
     CDS             complement(13641..14186)
                     /locus_tag="KRL22_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH1273675.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(14409..15353)
                     /locus_tag="KRL22_003231"
     CDS             complement(14409..15353)
                     /locus_tag="KRL22_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH1273676.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
BASE COUNT         5411 a         2420 c         1954 g         5718 t
ORIGIN      
        1 ataatataaa cacaggaggt acattctttg aaaaacatta tttcagcaaa agaacttata
       61 tcaaaactag aaaaaaatga taatctagtt gtaatagatt gtagatttga tcttatcaat
      121 agaacttatg gtattgattc ttataaaaaa ggacacatca aaggcagttt tatcttagat
      181 atagacaagg atttatcatc tcctacaaaa gaacatggtg gtaaaaatcc tttacaagac
      241 cctttaatac taaaagaaaa attagaaaaa atgggtgttg ataatgacac tacgattgta
      301 acttatgatg atggagattt aaatggagct tgcagattat ttttccaatt aaaacatttg
      361 gggcttaaaa atgtctatgt actagatggg ggaataacat ctttcgtaaa ggaaggtgga
      421 gaattggaag agaaagtgaa tataccaagt tgtacaggta aggaaattag accaaatata
      481 agcaatgatt tagttgttcc aatggaatat gttaagtcta aattatacaa aaaagatact
      541 gtaataatag attgccgtgc taatgagaga taccagggtt tagttgaacc tgcttactca
      601 aaagctggtc atataccaag tgcaaaaaat tatttttgta aggatttaat aaaaagtgac
      661 tttgaaaatg gctcacttaa agatatagaa tttttaaaaa aattctttaa agatttaaat
      721 aattatgatg aagtaatttt atcttgtggt tcagggatat ctgcttgtgt taacagtctt
      781 gctcttagag aactggatat acctcacaag atttatattg gtagctttag tgactggatt
      841 agttatgatg acaatgaaat caaaactggt caagaataag gctcataatc tatataaaat
      901 cagcatatga tagcttaagt tttgtaaagg cgtcagtcat tgtagacttt cgcctttact
      961 tattatttca tatactcttt aaatttatta tatatatttt agttgataat attaataaac
     1021 tgcaatatga ccatcacatc ttgactccgt cccacaaata taactttcct gttctgtttt
     1081 aaatattatt tgacctcgtc ccatgtcaac agtatcatga attactttta tttcatgacc
     1141 cttttcaatt aatgaatcta ttatatgctt tggcatctct ggttcaactt ctatttcttt
     1201 tccttttatc cactgccatc ttggagcatc tagcgcctct tgtggattta atccaaaatc
     1261 aatcatattt gttaacactt gaatatgtcc ttgtggttgc ataaaagctc ccattacacc
     1321 aaatggacct attgctttat cttctttacc taaaaatcca ggtattatag tatgataagg
     1381 ttttttaaat ggttttacta cattgtggtg tttagggtct aaattaaaat tatttcctct
     1441 actatgtaaa gcaatcccag ttcttggtat cacaattcct gaaccaaaat ttatgtaatt
     1501 gctctgtata tatgaaacca tatttccatc cttatctgca gtacaaaggt atactgtacc
     1561 accacaatat ggctctcctg cagttggata caaagcctct ttattgtcaa tcaataaact
     1621 tctttttttg gcatactctt ggcttagtaa ttcctgaatc tttaccttca tatgctctat
     1681 atcagttaca tatgttttag aatctgcaaa agctaatttt aaactctcta taattttatg
     1741 tatgtcttct acattttcta tatttccttc taattccaat tcttttaata tgttaagtgc
     1801 cattaaaact gttattccat gaccatttgg tgggatttca aatattttat atcccttata
     1861 ttctgtactt ataggttcta cccatgttgg ataaaaacac tctaagtcac tctttcttat
     1921 agccccatta aattttttag aatattcatc tattttatca gcaagtcttc ctctataaaa
     1981 gctttcagcc tgagtatttg ctatctcttc taatgtactt gcctgttctt cacatataaa
     2041 tatatctcca gcctctggag ctttaccatc tttagaaaat gtatcaaacc atggtttgaa
     2101 ctcttctcca ataagttctt tttcatagag ttcatatgat tttttccata ccttagctac
     2161 attaggagat actacgtatc cctctcttgc atagtttatc gctggagata agcattccat
     2221 taagctaagt ttaccatatt ttttatttaa ttctgaccaa gctgctggta ttccaggtac
     2281 agttactgct ccaaacccat attttggcat ttctttcata ttattataat tttttaattc
     2341 catattttct ggagcaaagc cactagaatt taaaccatac aatcgttttt cttcctctat
     2401 ccaaacaagg gcatatgcat ctcctccaat cccattgctt gtaggttcta ctactgctaa
     2461 tgtggcggct gttgcaactg ctgcatcaac agcatttcca ccctttttta gtatttcaag
     2521 tccagcttga gatgctaatg gtgttgatgt tgcaactgct ccatttttag cgtacacgac
     2581 atttcttatt gatgagtatt tatgttggta ggcattaaac ttcataaatt tcagctcctc
     2641 gtcatttttt atttgatatt ctgcttagat ttattatata acatcaagta atgtaactga
     2701 tacaaaatga tataaaatat agactttttc ctaactttaa ttttatcttt aaataaatat
     2761 cttaaactca attctagtat tttctatctg cacttaaata agttatttta ttcaaaacat
     2821 atatctaatt cttttgactt aaaaataatt tattctttta tcatgtttag agcatatttt
     2881 aaagttaaaa aataatatat aaaatatcct ataaaataaa tgactagagt tatgataatt
     2941 ggtacaagta atgaccttgg tataaacttt tgtgctatag acatagcaaa taaattatga
     3001 actgtaccta caactaatgg cattaaaaat ataactttta actgttttga tattattttc
     3061 tcaatatctt tattatttgc tccaagtttt attaacataa tatatctttc cttatcatca
     3121 tatatatttg ataattgttt aaataagatt atactacctg tacataaaag aaatactaca
     3181 gacaaaaata tgcctataaa cagcattaga ccacttaatt ttatcaagtt attataactt
     3241 tcaatacttg atgtaaaatt aaaaggataa gtaaatttca tattttcact tactatattt
     3301 tttaatttta aagtcaaatc cagttctttt ttttcatttt ttatatcaat taatcttatt
     3361 aatctagaat ttccatgtaa ttttaactga ttaaatacgt catcttttac tacaattaaa
     3421 tcaaacgtag cttgtgaatt tatttctggc tccaagatgc ttttttgtac tttaaacaga
     3481 tttatatcat actcatttgt atctttaata tgcaagttta ttttttcaac ctcaaagtct
     3541 ttaaaaaata tttttttgta tgaatcagaa acatagtaca cagattcctt tgaagttaat
     3601 tcttcataat tgttattctg atattgtctt aattttttaa aatcactttc tctaataata
     3661 tctacagacg ttctatcttc tatataacta tttccatttt tataatacat ttcaatattt
     3721 atatctttgt ctataagttc tattgtttta tcaaagatta tcttattatc ttttttatat
     3781 ttatataata atttgtcaat tttgttattt acataagaat ttcctaaatt tatggtataa
     3841 ctgtatttat aattttcact tatgttccta tctatatcgt aataaagtga tatggtaaac
     3901 cctagcatag ttacacttgt agctattaat attgctatta cagccaatac actactattg
     3961 ctctttaatt taaatccaag ttcagaaaat gcaattaaat tctgtccctt ataataaaaa
     4021 ctttttctct tcttaacagc atcaataatc atatacatcg ttgatgaaaa aaataaaaaa
     4081 gttccaggta ttattgtaac taatataaaa actgaaagca taatattttc agcaataaaa
     4141 taactaattg acattaaata agaaatagct attaataaaa caccaagtac acattttaac
     4201 tttataaatt ttttaaactt atacttttct ggatatttat taaataactc tataattctc
     4261 ttatttctga taactatagt atttcttatt ccaataacta taaatattat taaaaatacc
     4321 gctagtgtct gaactaaggc ctttatactt aagttcatat ttactactat catttcattc
     4381 attaatttta caagcatcat agtcataagc tttgaaaata acagtcctaa aaatatacct
     4441 attagtattg caactatacc catcaaaaaa gtttcatata aaaatatttt tcctatctga
     4501 tttttcctca ttccaagtaa actataagtt cctacttctc gcctacgtct attgaaaaaa
     4561 aatgagtttg aataatatat aaataaaaat acaaatacca ctattacaat tgaacttgta
     4621 ttaatactca tcctggtttt ctctccaagt gaactcaacg cttcattata ctctatagat
     4681 ttaaaactaa aaaatacaaa tacactaaat acaattgaaa taaagtacat taaataatta
     4741 aaaaaactat tctttacatt ttgcattgca attctaaata aagtcatttt tattaactcc
     4801 tccaattaag gaaactgtat ttactatttt attatagaac tctctgttac tttctccctt
     4861 tacaatttct gtgaatatta ttccatcctt tataaagagt attctattgc aaaaactcgc
     4921 acttatagca tcatgagtta ccatcaatat tgttttattg ctgtctttgt ttaattttaa
     4981 tagacaattc aacaaatccc tagcagattt agaatctaat gctcctgtag gctcatctgc
     5041 aagtactaat gatggttttg ttgctatagc tctacataca gctcctcttt gcttttgtcc
     5101 accagaaact tcgccaggat atttatctaa tatagattct atatttaatt cttttgaaat
     5161 ctcttttatt ctattttcta ttactgatac tctttcattt tttaaagaaa gaggcaacat
     5221 tatattttct tttattgtaa gtgtatccaa aagattagaa tcttgaaata caaagcctag
     5281 attatcacgt ctaaaatctg ccaattcatt ttgcttcatt ttaatagtat tctttccatt
     5341 tatataaata tctcctgatg aaggtaaatc tattgtagaa ataatattta aaagtgttga
     5401 tttaccagca ccggaagacc ccataatacc aacaaattct cctttataaa ccttgaaagt
     5461 tattcctctt agagcttcat gttttgaacc ttttcttcca tactcttttt ttatattttc
     5521 agcagataat atttcttcca tagttaataa tcacctttca tcacaattag ttatttatca
     5581 attctcacaa atatattata tatattaaaa tggcttttaa acatttaatt atattaattt
     5641 aaggttacat tttcgtaagt attaattata tttcttcaaa tttattgcaa ttatgtttaa
     5701 aatataattt atcaagtaaa atatagttat attaatataa ttattttagg taataaggta
     5761 gaaatatttt aatttatcaa gtagaatata gttatgttaa tataactatt ttgaattagg
     5821 aggtaagaat gtttaaaata atggtagttg aagatgacgt ctcattgaaa aatatcatag
     5881 caaagtgtct tactaaatgg ggacatgatg ttcatcaaat agaaaatctt gaaaatataa
     5941 tagaagagtt caaaaactat aacccagaat tagttttatt ggacataaac cttccatttt
     6001 atgatggttt tcattggtgt aatgaaataa gaaaaatttc aaaagttcct ataattttta
     6061 tttcttcaag aaattctaat atggatgtaa taatgggtgt aaatttaggt gcagatgatt
     6121 atatacaaaa acctttttct gtagatgtct tagtagctaa agttaatgcc cttttaagaa
     6181 gaacttataa ttttgttgat aataactcaa atcagattat tcacaatggt gttactttag
     6241 atttatcaac tgcaacaata aactatgaag ataatactat tgagctaaca aaaaatgaaa
     6301 tcaaaattct ccatgagctt atgaaatata aggggcagat agtaagtagg aataaactca
     6361 tgaaaaaatt atgggataat gattggtttg tagatgataa tacattaact gtcaatgtaa
     6421 atagaatacg ctcaaaatta aatgaaattg gtttagaaga ttttatagaa acaaaaagag
     6481 gattgggtta tataatcagt taaaacaatt ctaagtaggt gaatttatga gctttaaaga
     6541 ttttctcaag gataaactag gttttttagt atacaatttt actttcttaa tttttacagt
     6601 atcagttatt atattttctc ctgtagatgt ttttctgact gatactattt tatatatatt
     6661 agttgtaaat gttgtgtttt tatttttata tctatttatt agctacatca agaagaacaa
     6721 atttttagat aagataaaaa atgatacatt caaaattaat atgaatgata tagaattagc
     6781 tagatgtaaa aatgaagaaa aaatatactt gaacattatt aaaaatcatc aatatcaatg
     6841 taataacata ataaataata atatcgagaa atttgaagaa aacaaagaga ttttaaatat
     6901 gtgggtacat gatgtaaaga tacctatagc tataataaaa ctcattcttg aacaaaatga
     6961 aaatttaatt gatgaaaaaa tttcagatga catagatagt gaaatattta gaattgaaaa
     7021 ctccgttgaa aaaattttat atttatcaag actcgaagat tttcataagg attttttaat
     7081 tcaagaggta aatattgaaa aaatcattag aaatattata aaaaaatact caaaatattt
     7141 tatttcaaaa aaaattattt tagacttaaa taatttgaat tttaaggttt tatctgatga
     7201 aaaatggcta tacttcatat tcgagcaatt attgagtaat tccctaaaat actcctcatt
     7261 aggagataat atatctatct attgcaaaag aaccaaaaat tatttacaat taagagtgga
     7321 agatactggt tgtggtataa aaaaggaaga tttaaatcga atattcaata agggatttac
     7381 aggtaataat ggaagaaaca attctaaatc tacaggtctt gggctttatt tagtaaaaga
     7441 actttgtgat aagcttggtc ataaaattga tgtagattca gagtacaacc aatatacaaa
     7501 atttactatt acattcaaat gtgatttata gtatcttatt attgatagtt tattttcatt
     7561 aacttatatt caacttctta tagtaattct atatgtacat cccagtatat aattaagtag
     7621 tttttataaa aaggaggaag acatgtcttt tctaaaaaaa tttaaaaata aaagatttag
     7681 aaataacagt tttaaaagta acaactttag aaatagcagt tttggaagta gtggcttcaa
     7741 gtctaaaaat aaaggtttta aaaacaatcc ctttaaaaat aagagattca aaatatatgc
     7801 aggaatagca gtaatcatac ttttaattct aggagttctt gcttatgttg attcgaaaaa
     7861 cactgaatta caagctaatg aaaattttat cgaaacatat actattcctg aaaatgaaaa
     7921 aatatttata aatgggatgg ttgttcctaa gcaaactaag gacttcaata tatctggaga
     7981 ttatgagtta agtgatgtta atgttacaaa tggtcaaaaa gtaaatcaag gagaccttct
     8041 ttttactgct aaaaatccaa ctataatagc agaaatagat agtttaaaat cacaacttag
     8101 tcaatacaaa aaacaaaaaa tatcactttc tgatattgct gaaaataaag atgctattgc
     8161 ttctataaat gcacagataa ctgctttaaa ctctcagata gcttctctgg ataaaaaagc
     8221 ttatgacaga gttactgctc cttttgatgg cacagtatac ttgaatgacc aaactggaaa
     8281 tccagaccaa ccagtttcat ttatgactat tcaaggtcta gagttttata tgaaaggaca
     8341 agcaagtgaa caagatttac ctaaaatgaa gattgaccaa atggtcaata tactagtttt
     8401 ttcaactgac caaaagctta ctggtagaat aagttttata tctgataaac catctactcc
     8461 aaatactgaa atgggagctc agcagaatac actatcttat tatgatataa acatagcatt
     8521 tgataatcaa gaaggattag taaatggatt ccatcttcaa gcatcacttg aagtagctaa
     8581 ttcaagcttt aaaataccag catcttgtgt acttaaagac aacaaacact catatgtatt
     8641 taaggattta gatggtatat tgaaaaagca aattgtagat gtagcaagtc aaaatgatga
     8701 ttttgctgta gttagaggcg gtcttgaaca aggcgatata ataataaaac accctactaa
     8761 agaaatgaaa gaaggagacc cagttcaagg cgatggcgta actgctggtt ctaataatgg
     8821 agatactact ccaaacaaaa aagtagaaga agttactatg gatgtgaatt aatttacata
     8881 tgttaattaa attagaaaat attcaaaaat attacaaagt agggaaagat gaattacatg
     8941 ttttaaaatc cttaaattta gaaattgaat ctggagaatt tgtcatgata atgggtaagt
     9001 ctggtagtgg taaaactact ttacttaata tcttaggttt tctagatgta tttgatgaag
     9061 gaagatatat atttgatgga acagatgtaa ctaatttgag tgaaaatgaa cgttctgttt
     9121 ttagaaatat taatattgga tttgttttcc aacaatttaa tttaatagaa actctaaatg
     9181 tatatcaaaa tgtagagttg cctctaattt acaataaagc actaaaaaaa tctaatagag
     9241 aagaaattgt taaagataaa ttaagttctg ttgggctttt ggacaagctt aagcagaaac
     9301 cacttcaatt atctggtggt caacaacagc gtgtagccat tgcacgttgc ctagcaaatg
     9361 accctcagat aatctttgct gacgaaccga ctggggcatt agatagtgaa actagcagag
     9421 aaattatgga gcttttaaca aggctcaaca aacaaggtaa gactataata atggttacac
     9481 atgatcaaga tttaactaag tatgcaacta aggttatacg acttaaagat ggtgtgttta
     9541 cttcggaggt gtaatcatga gtttattaaa aaattctttg gccaatttaa aaggtcacaa
     9601 gcttcgtgta tttgtagctt tactctggat tataatagga ataacttcag taatacttgt
     9661 tagttctata ggtaatggat ttcaaaaaga aattaagaag tctgtaaaca atgtaaaccc
     9721 taataaaact actatttcgt ttgaatcagc cgataacaca ggtcttactg atgatatgag
     9781 tattttttta aaacccttta atgcaaaaga tttagaagaa ttatcatttg ttgaaggagt
     9841 agaaagaata gctccttcaa gagatgggtt taaccttgat tcagtttact cttcacaagc
     9901 atcttttgat aaaaaaacta cgtatgttga tgttggacca gtaaaaaaag attctaaaat
     9961 aaatttaatt tgtggtagag atttttcttt agatgatgaa aaaagaaaag taattttact
    10021 tacattacaa agtacaagtg aaatttttga aaatccagaa gatgccttag gtcatggtat
    10081 caacataaat ggaactatat ttgaaataat aggggtatta gatgattctc agcaaaacca
    10141 agctggagga ttctttggag gttaccaaga tatgcaattt actacttccc tagtacctaa
    10201 aaaggctttt gacactttaa tgagtcaaaa ttcttattca aatgaaattt accagttaga
    10261 cttagtttct tctaaaggct ataatgtaaa tgaagttgca aacaatgtta tagctaaatt
    10321 atatgagatg caccctggta tcaatggttc ttatactaca ccagacccaa ctgaacagac
    10381 agcttatctt gaaagcatta attccaatgt aaacaaatat gtatctataa taactgtagt
    10441 tgcaatgttt gttggtggta ttggtgtaat gaatataatg tatgtatctg ttatggaaag
    10501 acaaagagaa attggtataa gacgtgctat tggagcaaaa cctaggtcta tattatttca
    10561 atttttagtt gaagctgttt ttataacagt atgtggtgga attttaggaa ctatagttgg
    10621 atttgctgct actaactatg tttctaaata tataggtttt gaagctatac ctagcttaaa
    10681 tagcttattt tatgcaattg tagctactat attgactgga gttgtatttg gtctgattcc
    10741 agcctttaaa gcctctaaac tagaccctat aaaggcaatt tataagtaga aattgtataa
    10801 agattttcga tttttagatt agtttatata aaacatactt aaatatataa cgcactatta
    10861 tatatgatag attaggaact taatctttcc aaatataata gtgcgttctt tcataaaaag
    10921 gattctcttc cttactatat ctaaattacc aagatgttat gttctaattg ttcaaactaa
    10981 tacttccaat tttgattaat caatctcatt ctcctaatat acaatctttt actttcaatc
    11041 attgtacact ccgcctaaaa aaaataatct taaattaggc gttatataca atctccccat
    11101 tacatattgt ataattaacc tttccatata aagatttacc tttaaatggt gaattatcag
    11161 ctttagaaac aaagctttca actgtccatt cttcttctgg attgaatata acaatgtctg
    11221 ctacagcccc ttcttctata aatccaatat ttaaattgta caactttgca ggatttatag
    11281 acattttttc tattaactgc atcatactaa gatgattttt atgcaccaaa tttgttattc
    11341 caagagctaa agaagtttca agcccaataa ttccacttgg agcttttata aactctctat
    11401 ctttttcttc tttactatga ggtgcatggt ctgttgctat tatttcaata gtaccatcat
    11461 ttaatccctc tataatctta tctctgtccc atttacttct tagaggtgga ttcatttttg
    11521 catttgttcc aaactccaat acatcttcct cagtcaatgt aaagtgatgt ggtgaagctt
    11581 ctgcaactac atttgcacct aagtattttg caaatctaac catatcaaca gatacacctg
    11641 aacttatatg ttgtatatca actttagcac cagtctttag tgccaacata caatctctgg
    11701 ctaccataac atcttctgct acacttgatg caccttttaa tccaagttct gaagctacct
    11761 ttcctgcatt tacacctgga tttccaacta aagaagggtc ttcttcatga aaactaagtg
    11821 gtacatccaa ctcttttgcc ttaatcattg cctccataat tagattgcta tccattaaag
    11881 gtaatccatc atcagtaaac cctggtacac cagctttttt aagagcttcc atatcaacta
    11941 actctttacc ttcaaaacct ttagttatag ctgctgcttg taaaacattt atacatgcat
    12001 tttttgactt ttctttaaca taattaaaag tatcttcatt atctacaata ggattagtat
    12061 ttgccataca tataacagtt gtaaatccac ctctagcagc agatttagct ccactttcta
    12121 tatcttcttt atatgtaaac ccagggtctc taaagtgtac atgtacatcc actaaacctg
    12181 gagcaactac attaccacta gcatctatta ttttttcata ttcatcactt tcatcaaact
    12241 tgcctatttt ataaatttta ttttctttta taattaagtc aatattctca tctctttgac
    12301 ttttagggtc tattactcta ccatttttaa ttaaaatcat attatttctc ctttatattt
    12361 ttaatttata tagactcata taatattata cattatttta catacttaaa tacaaaatta
    12421 cgtttgacat caatagcctt tttaggacaa agttcatggc aacagtaaca tcttatacat
    12481 ttacttaagt ctataatagc acccttagtc cctatctcta tagtggatgc aggacaagct
    12541 tccttgcatt ttccacattt tatgcaatct tgaaatctta ccacaggctt tggtgttata
    12601 agctttgaaa taggttcatt taaaaatttt ggtagcttta cggaaaacaa tcttaaatct
    12661 ttacttacat ttggaatctt gtaatttttt ataattaaat cttttatatc ttcacctaaa
    12721 atttcaatat ctgaaaaatc ttcttgtata tatcctctct taatagcacc tctaattgta
    12781 gcaactctat ttggaagtaa acttataatc ttacatgcaa caacatctat agcatatgga
    12841 ttttgtgatg ctaataaaac tcctatttct cgagtagtac cagctgaagg tccatcacct
    12901 tccataccta ctataccatc cataattgtc aatgttggtt ttatataatc acagatatct
    12961 aaaagtacat tttcgcaaaa caactcttct gtaggaaatc tataatgtat ctctgctttt
    13021 ttcaatccag ctatgcatcc atataagttt tttgtaccac cagtaaaagt tgccattata
    13081 tgagtcttta atttacaaag atttattata taatctgaat ctactattgg tttaataata
    13141 tccatatatt ttagaacatg tgctttttca ctatgtatct taacatctga aacatcataa
    13201 tttaacttaa tgcccagttc atttgctact tcttcaattc cagatgcctt ataaatgctc
    13261 ttaagagaat tttgattata tggaccacca gggctatctg ctattgtaat atcacaattt
    13321 aactctaaaa gtttttcaca tacaactttt acaaccatag gatgtgtagt tgtagcttct
    13381 tcaggctttt ttttcatcaa taaatttggt tttataagta ctttgcttcc ttttttaaca
    13441 aacttatcta taccaccaat atcctctaaa tttttttcaa tagataactt tacttcttca
    13501 taattgtaag ttttacaact tctaacagat accgacttca tattatctcc atccttctat
    13561 cacaacagtt tatttgtata atttaaaaaa ggagaaacca aagtttctcc ttttaatcta
    13621 tgttttaatt gttttaatta ttattttcca aaatgtctgt ttaataatcc taagaatgct
    13681 ttaccatgtc tagcttcgtc tttacacatt tcatgtactg tatcatgtat agcatctaat
    13741 cctaattctt tagctctctt agctaatttt aattttccat cagttgcacc atactcagca
    13801 tcaactctaa ctcttaagtt ttcttttgta tctgcaacta caacttctcc aagaagttct
    13861 gcaaatttag cagcatgttc agcctcttca aaagctattc tcttatacgc ttcagctact
    13921 tctggataac cttctctatc agcttgtcta ctcattgcta aatacattcc tacttctgta
    13981 cactcaccag taaagttggc tcttaatcct tcgattattt ctgcatctac accttgagct
    14041 actcctattc tatgttcatc agcccaaacc atttcgcctt tcatttcttc aaatttatca
    14101 gctccaactt tacatactgg acattgtgct ggtgcagcat ctccttcatg tatatatcca
    14161 catactgtac aaacaaattt tttcataatt aatttcctcc caattttata taattaaatt
    14221 tttattttta agtttaataa cttgctacaa gaatatatat accccagact ttatagctta
    14281 aacactaaaa ataaaattta tttcctaatt aattttatca ctttgaaaca ccagtatcaa
    14341 ccaagttttg atgtcaaatt tctacataat acataattta tttgattaat taggaaatag
    14401 ttgtcatatt aaatactttc taatgaagac tcctctgaat ctttaagttt cacttttttg
    14461 ctctttaaaa aagataattt agtttctgca gttatgattg caacaaatat caagatacta
    14521 ccaataacca attttgctgt aataagttcc tttagaatta ttatagaaaa tattgtacca
    14581 aatacagcct ctgtggataa tattatagct gttctagttc catcaactct tttttgacat
    14641 atagtctgaa ataaaaatcc aattgtagta ctaaatacag ctagatacat agttcccatg
    14701 taaccagata attcagcttc catctttaat tgacctgcaa atgtttgaac tacaacagac
    14761 attaaaaacg ctactgtaaa ttgaatagct gtcaatgcca ttgggttgtt atcttttgca
    14821 aactcacttg taaagaatat atgaaatgca aatccgaatg aacatataag tgttagaaaa
    14881 tctccaaaat taatagagaa atcagcttct aaagaaagta tcccaattcc tataagagct
    14941 accaaactac ttattattcc tattttatca agttttcttc tataaagtat aaatcctatg
    15001 aacggaacta ttacaacatt agctgctgtt ataaacgcat ttttagatgg tgtagtgtac
    15061 ataagtccaa tagtttgtac tgtgaatgct agaaataaaa atattcctaa aatccctcct
    15121 gcttttaata attttttacc catattggca cgaatctgtt taaaaaacag taaattcata
    15181 attatagctg ccaagaaaaa tcttaaagtt atgatttgta gaggtgtaag cccaccgtct
    15241 aatgcaaatt gggttgctac aaagccactt ccccatataa ttgctataaa tattagtcct
    15301 atttctccaa agtatttttt caataaagcc ccctcctttt tatttttttg caaaattata
    15361 aaccccctaa acagcaagag agtttttcta taagcattac tataaattaa tatagtaaat
    15421 tttttcagta ttttaaatct aaatttacat acattttgag ctcaaattta tatccactat
    15481 ttaacagtaa tatattaatc att
//
LOCUS       DAEPUT010000096        15084 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.099, whole genome shotgun sequence.
ACCESSION   DAEPUT010000096 DAEPUT010000000
VERSION     DAEPUT010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15084
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.099"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..847)
                     /locus_tag="KRL22_003232"
     CDS             complement(<1..847)
                     /locus_tag="KRL22_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1273677.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVGNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLSDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLK"
     gene            complement(1062..3080)
                     /locus_tag="KRL22_003233"
     CDS             complement(1062..3080)
                     /locus_tag="KRL22_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH1273678.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            complement(3350..4126)
                     /locus_tag="KRL22_003234"
     CDS             complement(3350..4126)
                     /locus_tag="KRL22_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH1273679.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(4183..5154)
                     /gene="asrC"
                     /locus_tag="KRL22_003235"
     CDS             complement(4183..5154)
                     /gene="asrC"
                     /locus_tag="KRL22_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HBH1273680.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            complement(5167..5958)
                     /gene="asrB"
                     /locus_tag="KRL22_003236"
     CDS             complement(5167..5958)
                     /gene="asrB"
                     /locus_tag="KRL22_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HBH1273681.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            complement(5959..6966)
                     /gene="asrA"
                     /locus_tag="KRL22_003237"
     CDS             complement(5959..6966)
                     /gene="asrA"
                     /locus_tag="KRL22_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HBH1273682.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVTSKEE
                     V"
     gene            complement(7383..8573)
                     /locus_tag="KRL22_003238"
     CDS             complement(7383..8573)
                     /locus_tag="KRL22_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1273683.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYSWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLNDGIDTAGGKMTVCQLYEKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSEKGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEQKVILTPEQEERLLAFMEKDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRILNIDHQLLKDSEIGYYIETPKTKNGKRELPLTE
                     RAYQAIQRILKNRGKAQPLIVGGYSNFLFLNREGLPKVAGNYEGMVRGLIKKYNKYHT
                     DKLPNITPHSFRHTYCTNMANRGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(8652..8855)
                     /locus_tag="KRL22_003239"
     CDS             complement(8652..8855)
                     /locus_tag="KRL22_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1273684.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENIDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(9228..9482)
                     /locus_tag="KRL22_003240"
     CDS             complement(9228..9482)
                     /locus_tag="KRL22_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009264382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273685.1"
                     /translation="MKQLFKKPSYYLISSAMDGNEKAIEKLLAFYDPYISKCCLRSLY
                     DEYGNVYIVVDMELKGRIREALIKMILGFDIEDMDLELEE"
     gene            complement(9486..9905)
                     /locus_tag="KRL22_003241"
     CDS             complement(9486..9905)
                     /locus_tag="KRL22_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1273686.1"
                     /translation="MKPSDFQKTVQCRFESCLKKVVRSVVKDYYKELNRRKNKEISFS
                     ELPDVLVDKMAVWDDYETDYTIFSVCGIDIRVLDDELAEALKKLPERKRNTLLMYYFL
                     EMTESEIANLQKITQSGVFRNRHHALETMKKILREEH"
     gene            complement(10200..11204)
                     /locus_tag="KRL22_003242"
     CDS             complement(10200..11204)
                     /locus_tag="KRL22_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1273687.1"
                     /translation="MSFFAFLEEKIIEILFQLFFLALVAFLLTFYGVDTLFVVLLVIL
                     FIVIQGLFQWCLYRKKRNASQQIIDLVDGLEETYYIADVLPKPKEFQNEAYYYALKKA
                     CKSMNDEIGKITEEKQDYQEYVESFAHEIKIPIGALSLTFDNTKNYTLKKETDKIFQL
                     VEQMLYYARSENTEKDYFVKQLQLDEVIHNVILKFRHSLMERKTIINIHDIENVVYAD
                     EKWLTFILSQIVQNAIKYFDKQENELTIYSQDNGTNILLVIEDNGCGIKTSDLSRVFE
                     KGFTGSNRNKANATGMGLYLSKKLCDRLGLKLDIASTEKEYTRLTITFPKGTVHNFSE
                     "
     gene            complement(11201..11860)
                     /locus_tag="KRL22_003243"
     CDS             complement(11201..11860)
                     /locus_tag="KRL22_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HBH1273688.1"
                     /translation="MRIAIIEDDEITRLELSKLLNTQGYETVLLTDFENLTEELKQYS
                     IELVLLDINLPYENGYEVCRKIKQVMPVPIIFVTSRDTNADELKSIQVGGIDFITKPY
                     DTLILLEKIKRALQLSNPNNFRELVKKDCTLDLHLSILKYQEKSIELTRNEFRILYYF
                     FMNEDKVISKEELLEKLWNDKYYLDENVLLVNMTRLKKKMKEIGIVHLLENIRGKGWK
                     L"
     gene            complement(11920..13896)
                     /locus_tag="KRL22_003244"
     CDS             complement(11920..13896)
                     /locus_tag="KRL22_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273689.1"
                     /translation="MLGKLAVRNTKRSLKDYLIYLITITISFSLILAYNLVASSNEVV
                     ELSSGMETFKTILTFVNVIIIFVVCFLINYTTRFMFEKRSKELGTYMLLGIKKKVIAR
                     LLVSENILLGIFAFILSIPLGFIFSQFVSLVIVKLLGIPEVIFISMNFASIELLAIYF
                     LVIYVLVLLNLLRRIKKMTVHDFLYFDKLNEKKMFHSSKIRNIIFVISAIIGVVSLLL
                     WNSQFDIKKIGGSEIITYLMISLIMLIISIYGIYATFSDMLLSILLKSKKCKYQKDNL
                     FVARTFASKARTMSFTFGTLSMLILISLICLNFSSINKGMYKSTIELNAPYDVDLFDE
                     NNTFKNIDKFLCIIDEDYTINQTVEYNIYKEPNYQIQNYYAVEFYNYDPVMKLSDYNK
                     LLKIRNMDTIKLNKDEYLLVTPNELLYKVENNNDIKNIQFSGNELRLKEIDTKSYWDA
                     MNNTGRFTIVVADECVQGLEISERHLIVDTKEDTTTKLEEKLEKEAELQLAETKENKE
                     SDGHYYYIHTRGSEIEQQNTMTATIASLCLYIAFILISAVGTILAVQSLSDAAKYKYR
                     YLTLRRLGVNNETLFKTIRKQLIILFGVPVVYSVIASFCMAFSVNNVYQILLTSRFIY
                     LIYFAGSLAILFLLYGIYWIATYIGFKRNINEES"
     gene            complement(13886..14656)
                     /locus_tag="KRL22_003245"
     CDS             complement(13886..14656)
                     /locus_tag="KRL22_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273690.1"
                     /translation="MEHILNLEQVKKYYGGNSGNITKAVDGISMYVDKGEFVAIMGAS
                     GSGKTTLLNCISTIDTVTSGHITVNNQDITKIKDKDFADFRRENLGFIFQDFNLLDTL
                     TIEENISLSLVINKQNPADIDKRVHAIADKLGIRDILSKFPYEVSGGQKQRCACARAL
                     INEPKLILADEPTGALDSKSSRLLLETMSDINKKMQATILMVTHDPFSASFCKRILFL
                     KDGKIFNEIFRGEKSRKDFFNEILDILTLLGGEVGNVR"
     gene            complement(14823..15053)
                     /locus_tag="KRL22_003246"
     CDS             complement(14823..15053)
                     /locus_tag="KRL22_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273691.1"
                     /translation="MIGLKKRDIKKALKAGAKAGGMSLADVRENIEATIDEAMNSTDP
                     EVQANFKKYFGNKRPTPEEYIYIITKKTKVKL"
BASE COUNT         4653 a         2855 c         1848 g         5728 t
ORIGIN      
        1 tctttaaaaa tttaatgata ctattggcag taatattaag ttgtttttct tgacttataa
       61 tagcatcatt atctcccttt tgttttccat aatctccaaa ttgtgcatga tttcctcctt
      121 caatctcaac ataagttgta tcatcagaaa gtttttgttt tgattctaca agacttttaa
      181 aattgactac tccatctttg ctcccccata tagatataac tttttttcct aattctttca
      241 actcatcacc cattggataa gaagctaaaa atacaacgcc ttcaattaat ttattatcac
      301 gtgcaaaatt tgatgctgca actcctccta atgaatgacc tcctattacc caatgttcta
      361 tgttgttgta agaatccata actttctgtg ccttattagt tccaagtata gctagattaa
      421 gtggcatctt tacgattaca acctcatatc cactttctgc tatttttctt gcaagtggag
      481 cataagattc tatttctact ttagctcctg gatacaaaat taaaccttta gaaacttttc
      541 ttccttttgg tgtaaatgaa atgttttcat ttacagttac ttcaacttta ctattgccga
      601 ctagagcttc ttttgccagc ttttgaggtt catatgtttt atttatccat atgaaaaagc
      661 caagcaaaat caatacaaat agtataccta ttcccttaaa tatcttattc tttatgttaa
      721 attttctatt attattttta tcatctttgt tctcaacctc atcataaagt aaaggtctct
      781 caagttccat agttatacta aatgtatcat atttcttatt acgctttacc tttacatctt
      841 tactcataaa tctaaccccc ataatatttg aatactatta tagtttatcc taagtaaatt
      901 gttttttcaa ccaatgaaaa aaatcaatat tttaactatt ttcatataaa attcataaat
      961 atatgttttt tgttttttat atattatttt cttttagtat tttataaagc aaatagccat
     1021 atactttatt ttaaatatat ggctattcta taatttaata tctaagctgc ttcttttatt
     1081 gaaactttag ttatattact tattctatac atttctttga caccatttag agtttgcagt
     1141 aagtttagac atattatctt gtcacctaga cttttagtat ttacaatact ctctaaaatt
     1201 acacttcttc cttcatcata cttatctaca ttgtaatttg aaatataatt agtatctctc
     1261 aatatttttt caacatcttc atcttttatt ttatttttat taacatttat atatagatta
     1321 tacatattac ttattagtaa tttctgattt tctaaaaaat cctcttgatg tttatcttta
     1381 tatatagcat ttatcaacat aagtctatct tcaataagtg atggtatcaa taataaattt
     1441 tttatatagt aaacatcagc tacattttct atagacttat tgacttcatc aattatattt
     1501 ttaactattc ctttatacat ttctataaca tgttgatagc ctgttttagc atcatatggt
     1561 aatataaact tatttactat taatgcaata attgctccta atgctacata tgaaatcctg
     1621 cttatggtta aaacatttgg gtctcccata actactgctg aaccaagagc tgaaacagtt
     1681 acacatacca ttaattttct ataatcaact acataagagt ttatataccc tgctaaaaga
     1741 actattaacg accttaatgt actatctttt attattgaaa ataatacaat aaatattaca
     1801 gctcctataa atgtaccttc tattcttttt ctagaccttt gtatacaatt ttctgcgtaa
     1861 ggttgtgtta atgaaaagac agttaacatt atccatcttc catctcttaa atggaaataa
     1921 tccataataa aacccgctac agctgtagct aaagcaatct ttactgcata agaaaatctt
     1981 atagaattta aattaaagtt tttcttatat attgatagtc gtttaaattc atgaggtatc
     2041 tttgattttc tttcagcttt cttttcgtct cttgatttta cttttttata atctactaaa
     2101 aactcatata aattttctaa aacactataa atttctttta aatttatatt tttagtatcc
     2161 tgagcaataa cataatctct aaatcctaat atctctttat cagttatggt atctttattt
     2221 tctaaacaca tcttaatata gtttatttct ttcgttgcta caactaaaac atctgattta
     2281 ctatttatgc tactttcttc taaaatattt tttatatctt catcttcaaa ttctttacta
     2341 tcctttttgt atctttccag gattaaactt attctttcta atgaaaataa aatattcatt
     2401 atgtctatac ctctaatact gatataaaag tcatcttttc tattatcaaa aataaccatt
     2461 ttcaaatttt tagatataga atttattcta taattacagc tatctatttt tctcatacta
     2521 gatttaatta tagaactatc atcattaata gtatttttta aaagactaat tttttctaat
     2581 aattcatcac atatagatat cagttcttta tctccgacat ttttcatcct atttctattc
     2641 ataacaaatt gagcaatcat tattataact gctccaacag ctaaagccga caatctcata
     2701 ggaaattcac tttttcctac aggtatactt accataaata tatacattag accaaaaggt
     2761 acatatactg ctctttttaa gtcataacta aatacatacc ctattataaa taatgctata
     2821 aaatttaata aaactcctaa atacatattt tgtactgcaa aaaatgatag tattcctaag
     2881 attatattta ttgctaaata cttcagtaaa tttttaattg gagaaatagt taaatctctt
     2941 tccaagagtg ttagcatagc tgttactata cctacaccta taagtgtatt tttacttcca
     3001 aataaatata taaatataga aataaatgct attataaaaa taaacaactt tgtttttgat
     3061 attactagtt tctttgtcat catatccccc ctaaaaattt caacaagacc aattttatca
     3121 tatttgttat cttattcaaa atgcgctttt ttacggtagg actttaactt tttttatatt
     3181 tagaactata taattcatat ataaacgtat tttttatata tataaccgat atattttcgt
     3241 atgctcccat atttttttgt ttcaaatatt ttttcaaaaa tataaaaata actctctcaa
     3301 taatactaaa aatgcattta tcaagagagt tataatttat acaataaatt taattaagct
     3361 tttctttacc taatatataa gttccaagac ccataaataa agctcctcca acaatatttc
     3421 caagtgttac agctactaaa ttataaatag ctcctccaat agtaactgta cttattgttg
     3481 gtgaaaataa tgaaacacta taaattgtca tatttgctac actatgctca aagcctgatg
     3541 ttataaaagc aaataaacat aagaatatca taattatttt tgcagtatca ctattagttc
     3601 taaacgaaca caacactgat acacatacta gaatattaca taaaatccct ctaaagaaaa
     3661 gagctgtaaa tggcatggat gctttactag ctgctgtatt tgcaaaaaat tcagctacag
     3721 gtcctttgtc tactagacca gttcctacaa atataatgcc taaaaccaaa gctccgatta
     3781 aattacctac ccaactgtat gcccatattt tagaagtatc ttttatactt acacctttat
     3841 ttaacatacc agcagacata accatattgt ttccagtaaa taactctgtt cccgtcatta
     3901 taaccaaact tagtgctatt gcaaatgata accccattac tatcttagtc ataggtgaac
     3961 ctgcatcagt caaaagtcct ccaatagtaa atatcaaaag tatacctata cctacataaa
     4021 gtcctgcaaa cgcagaagat accaaatatt ttactttact tgtgtttaat aaatttatct
     4081 tatttatagc tgcattagtt aatttatcca aagtttcttt atgcataatt ccctcttcct
     4141 tctattaaat tttaatttat tcaaatatat gttttactca atttatagat atttaattcc
     4201 actccagtat atgttttcgt acattttagt tatttctgga agctctacac cttcaagtgc
     4261 ccatttttta aattccataa atcctgttct atcaattata tatcctatat gttcttttcc
     4321 tcctggtgca tctttatcta tatacttttc tacatatcta taagtattaa gtattatctt
     4381 tattatgctg tcctcatcta cccataaaag aaaatcttct gctagtctag ggtttttctt
     4441 tcctgttcta cccattatag ctaatctata gtattttttc tcatctctag tccatgcatt
     4501 tgttgggcaa tttagtacac actctccaca gcctatacac ttatctttat ctcttaccac
     4561 cttattattt tctgttttta atgctccaac agatatctta gaacattttt ttacacatgc
     4621 tccacaattt acacatctat ccttttcata tattggtaaa gccataccaa taattccaaa
     4681 gtcattcatt ctagctttta tacaatcatt tggacaacca gttaaagcca ctttaaaatg
     4741 taaatcattt ggaaatatag ctttttctat tcttttagca aattcagttg tattatattg
     4801 agcctttgga cagactttat ttcctataca agctgctata tttcttgtac ctgctgctgg
     4861 ataacctgcg tttttctcac tttgatttat attcattttt tcaataacag gttgtataat
     4921 tttatttatt tcttccatat cttccatatt tattcctaat atttcaaacc cctgtcttgt
     4981 agttatgtgc acctgtccat tgccgtactc acttgcaatt ttagaaacta cagctaaact
     5041 ctcagggtca ataagaccac caggtactct aactcttaaa gaagtctcat attttgtttt
     5101 tgtaattcta taagcatttt tcattacttt tttggtattt aaatctctta tcacaaactt
     5161 caccccctaa tcaataagat ttttagcata tgaataatca aatactggtc catctaaaca
     5221 tatgtaagta tcatccattt tacaatgtcc acatttacct attccacaac acatttttct
     5281 ttcataagaa acccaaatgt tcttttcatc taaatctctt tttaaaaatt cttctactgt
     5341 aaatttcatc atcattggag gtccaactac aactatagaa gtattgttta tatctttcat
     5401 atccaattct ggtatgtatt ttgttactaa tcctacatta ccactatatc cttcctctgc
     5461 tccatctaca gtaactaaaa tatcaagttt tttactccat ctctttaaat catctgcaaa
     5521 taaaatatct tttggtgatt taaatcctac tattaattta aacttttcgc atttttcttt
     5581 attattataa aaatattcaa ctattcctct tacaggggct aatgcacttc ctcctgcaac
     5641 tactacaatt tctcttcctt cataaaggga tacatcaaat ccatttccat aaggacctct
     5701 tataaaaaaa gaatctcctt ctttataatt aaacaactcg ctagttactt ttcctacatt
     5761 tcttattgta aagtcaatat aatcctctcc atatcctgat actgatattg gactttcacc
     5821 gtatttaggt atagatatct cataaaactt tccaggcaat acaccttttg tattgcagtt
     5881 tactctaaaa gtccattctt tatcagtatg tttaactata tctagtattt ttgcacttac
     5941 tggtatatat gggttcattt atacttcctc cttactagtt actaaatcat ttattttttc
     6001 tatacacttt gaaaatgata tgtattgcgg acaggcatca tcacatcttc cacagccaac
     6061 acacatatga tatccgaatc tttttttaaa atcatgtatt ttatgcatag ttttaaatct
     6121 cattctttcg ccttgttttt ttctaaaaga atttccacct gctatatctg tatatccatc
     6181 tacttgacaa gaagcccaaa cccttcttct ctcacctaca ttttcgtttt ccttatagaa
     6241 aatatcctgc attgtaaaac atgaacatgt tggacataca aaattacatc taccacatcc
     6301 tatacatctt gtatcatatt catcccatat tgaatttcct atcatttcat ttgaatcaat
     6361 attctctggc acatctacag atattaaatt atcagttaca taatcaacat taaattcagt
     6421 tgcttctcca ttaaatactt caaattcact atcctttata tctaagtaca gtgtatctcc
     6481 ttctatattt aatccaattg aataattatc agttttgtta gaatccatgc tcacacaaaa
     6541 acagtttcta aaactttcct tacaccctac aagtgcaaac tttactttat ctctgatatt
     6601 tttataaaaa taatcttttt cttcaccatt atttagatat atttcatcaa gtctttttat
     6661 accatttatg tcacaagctc ttaagaaaat taaaattttc ttgttgtcta aatcgctttc
     6721 cttaaactct ttttcagtaa aataaaacaa tacttgattt atgggaagta caacttcttt
     6781 tggtgaaaag tttgctttct tagcaaattc catttcttca aaagcgttta cctccttgta
     6841 tcttataaca tcagtatctg aaaaagtacc tttaaatggg attaaaactg gtgcaaatat
     6901 cttgtagtct ttttttagat aattcagacc ttcattgaac ttagatgaat ctaattttag
     6961 tttcattttt atcacctttc ttatatttta gttttactta cttgctatct tgtttaaatc
     7021 ttaacacttt attttctatg cttccgtgat aattatcaca gtttcaaaaa taataaaaaa
     7081 aatattaatg gaatttatta agttctgtta atattttttt attatctaca ttattcgatt
     7141 tcaaatctaa tcacttaaat acaatcatta agtacaataa aactactatc tactcaattt
     7201 ttagaataaa aacttactaa atttctgatt atcttttcat aagttggtaa atgccgatat
     7261 atcccgtatt ttagggcttt atcggtattt tctttttgga agataccttg cataagctgg
     7321 catttaccag catgaaaatg caaccaaaag tagtaaatga gtagtaaata tacgctccga
     7381 tattaacaag ccagtctttc cagctctgct tttgcagatt gaaatgtacc gtgtgcgtaa
     7441 taaccaagtg tcatggttat gttagcgtgt cccatgagat attgcagggt gttagggttc
     7501 attcctctgt ttgccatatt cgtacagtaa gtatgtcgga atgaatgtgg tgtgatattc
     7561 ggtaacttgt ccgtgtgata tttgttatac ttcttaatca gccctcgcac catgccctca
     7621 tagtttcctg caactttagg caagccctca cggtttaaga ataggaaatt gctgtaacca
     7681 cctacaatca gcggttgtgc ctttcctctg ttctttagta ttctttggat tgcttgataa
     7741 gcccgttctg tcaatgggag ttcccgtttt ccgtttttgg tctttggcgt ttcaatatag
     7801 tagccgattt cgctgtcttt caataactgg tggtctatat tgagtattct gttctgcata
     7861 tcaatatgcg tcgtcagtcc gcaaaattca gaaatacgaa gtcccgtttc cagcagaagc
     7921 acaacctcat cataatactt gctgtaaatc ttatcctttt ccataaaggc aagcaggcgt
     7981 tcttcctgct ctggtgtaag gataactttc tgctctgtat catcttccaa aacatcactt
     8041 agcttaaatt caaacgggtt ctttctgata cagtcgtctt gtattgccat ataaaatgac
     8101 gctttcaagg aacgcttata gttatcaatc gttttatagg catatccttt ttcgctcatt
     8161 ctgatagccc attctttagc gtccgactgc ttcacagtat caatcgccct catacccaat
     8221 gggtcatttt tcagagcgtt cataagatac tgtcgtcctt tttcagtagc ccttttgatg
     8281 ttctttcttt ggctgttctt tttctcgtag agctggcaga ctgtcatttt accgcctgct
     8341 gtgtcgatac cgtcattaag gtcttttttt atctgtgctt ctttttccct caacgatata
     8401 tcatcacgct ttccagcagg tgtcttgtct gtcggtacaa gtttccaaga atagataaat
     8461 tgtggctttc cgtatatatc ggtatattta taaacgtatc ttccgtcttt tcgctggctc
     8521 tctccattac gcaaattgcg atttttactg tcttttcgtt ttacattaga catagtgtaa
     8581 agctcctttc cgtcatggaa tgagccgtga tacgctatat cttattatac catatctacg
     8641 gctcaatgac attagatttc gtccaatgta tctatgattt tttcaaattg ttttcgctta
     8701 atctgaatac gattaccgtt cacgataacc cagccagcgt caatattttc ttcggctaat
     8761 ttacgcaatt tcttttcgcc aatgcggaag tatttggacg cttcttcaat cgtcagcgta
     8821 tatttttccc agataggcac atcagtattg ttcataatct atgcaccccc tttactgtgt
     8881 gtcatttttt acaagcaggc agacggcttt ggaaagctcc gttagtatct caactattcc
     8941 cattcttgtg ggcagaaccg caccatgcgg acgtatcatt attctgtgag aataggtcgt
     9001 ggcaaaacga cttttccaat agtcgctctc ggatcactac gtgggtcgct cgctttcttt
     9061 tgaaaaggtc gtggcgtata gtccccgtgg ctcgctatct cacaaacgta tctgtctgct
     9121 ttattcagtt gtcaaagagc tgcggcgaaa gcgtgttgct ttcatgtaaa agcaggtgcg
     9181 gagcaggaaa gaggggggac attaaatcat gctccgccaa aaactgctta ttcttctagt
     9241 tctaagtcca tatcttcaat atcaaaacct aaaatcattt tgataagtgc ttctctgata
     9301 cgtcctttta attccatatc tacaacgata taaacattgc cgtattcatc gtaaagtgaa
     9361 cgtaaacagc actttgatat gtaagggtca taaaatgcca acaatttctc aatcgctttt
     9421 tcgtttccgt ccatagctga tgaaatcaag taataggacg gtttcttaaa taattgtttc
     9481 attttctaat gttcctccct gagtattttt ttcatagttt ccaaagcgtg atgtcggttt
     9541 ctaaatacac cgctttgcgt gattttctgc aagttggcaa tttcactttc tgtcatttcc
     9601 aagaagtaat acatcaacag agtattgcgt tttctttccg gaagtttctt caaggcttct
     9661 gccaattcat catcaaggac acgaatatca atgccacata ctgaaaagat tgtataatct
     9721 gtttcgtagt cgtcccaaac agccatttta tcaacaagga catctggcaa ttcgctgaaa
     9781 gatatttctt tattcttacg ccgatttaat tccttgtaat aatctttcac gacactacgg
     9841 acaactttct ttaaacaact ttcaaaacga cattgaactg ttttctggaa gtcagacggt
     9901 ttcatcaatc tcacctcctt tcctttatga tttgaaaagt gtttatccct ctttccgcac
     9961 catataagga cagctaggtg tgatttaatg acctcttttg aaaaattttt gaattttttt
    10021 cgggtatgaa aaaagcccgc acaaaacata tagtctgtac gagcctttaa agctaaaaca
    10081 tattcaattt ttaatagtgt gctattaggt gggatttgat tgcaaataat tgtacttaaa
    10141 gctttccata acgcaagccc ccttaaagca ccgtatcaat gttggcatgg tttttcaaat
    10201 tactctgaaa aattatgaac tgttcctttt ggaaatgtaa ttgtcagtct tgtatattct
    10261 ttttccgtag aagcaatatc caatttcaaa cccaatctat cgcataattt tttcgataga
    10321 tacagtccca tacccgttgc atttgctttg tttctatttg aaccagtaaa acctttttca
    10381 aatacacggg ataaatcaga tgtttttatt ccacagccgt tatcttcaat cacaagcagt
    10441 atatttgttc cgttgtcttg gctgtatatt gtcagttcgt tttcctgctt atcaaaatac
    10501 ttaatcgcat tttgcacgat ttgagataga atgaatgtca gccatttttc atcggcataa
    10561 acaacattct ctatatcatg gatattgata atcgttttcc tttccataag cgaatgacgg
    10621 aatttcagaa taacattgtg tattacttcg tctaattgca actgttttac aaaatagtcc
    10681 ttttccgtat tttcacttct tgcataatag agcatttgct ccactaactg aaatatctta
    10741 tcagtttctt tctttaacgt gtaatttttc gtattatcaa acgtcaaaga taatgcacct
    10801 atcggtattt taatttcatg agcgaaactt tccacatatt cttggtagtc ctgcttttcc
    10861 tctgtgattt tgccgatttc atcattcata gatttgcagg ctttttttag tgcgtagtaa
    10921 taggcttcat tttgaaattc ttttggcttt ggtaaaacgt ctgcaatata ataggtttct
    10981 tccagtccgt ctactaaatc aataatctgt tgtgaagcgt tacgtttctt ccgatacaaa
    11041 caccattgaa aaagcccttg tatgacgatg aacagaatta ccagcaatac aacaaatagc
    11101 gtatctacac cgtagaaagt caagagaaat gctactaagg caagaaagaa aagttgaaac
    11161 aatatctcta ttattttttc ttctaagaat gcaaaaaagc tcacagtttc caaccctttc
    11221 ctcgtatatt ttccaataaa tgaacaatac cgatttcttt cattttcttt tttaggcgag
    11281 tcatattaac cagtaataca ttttcgtcta aataatattt gtcgttccac aacttttcta
    11341 atagttcttc tttactaata actttatctt cattcataaa gaagtaatat aaaatacgaa
    11401 attcatttct tgtcagttca atgcttttct cttgatactt caaaatggat aaatgtaaat
    11461 caagggtaca atcttttttg acaagctcac ggaaattgtt cgggttcgat aactgcaatg
    11521 cacgcttgat cttctcaaga agaataagcg tgtcatacgg ctttgtgata aaatcaattc
    11581 cacctacttg aatacttttc aattcgtcag catttgtatc tctgcttgtt acaaagataa
    11641 taggtactgg catgacttgt tttattttcc tgcatacttc atagccattc tcatacggca
    11701 ggttaatatc aagcagaacc agttctatgg aatattgctt taattcctct gtcagatttt
    11761 caaagtcagt caataaaact gtttcatatc cttgtgtgtt caatagttta gaaagctcca
    11821 gacgagtgat ttcatcatct tcgataattg ctattctcat ttccacaccc cccttgattt
    11881 atcattataa taatttcaca gtaggagagc tagaaaagtc taactctcct cgttgatatt
    11941 tcgtttaaaa ccaatatacg tggcaatcca gtaaatacca tatagcaaga ataaaatcgc
    12001 caagctgcct gcaaaataaa tcaaatagat aaatctactt gtcaaaagaa tttgataaac
    12061 attgttgact gaaaacgcca tacagaaact tgcaataaca gaataaacaa ctggaacacc
    12121 aaacaatatt attagttgct ttctaattgt cttgaataat gtttcattat tcacacctaa
    12181 tcttctcaaa gtcagataac gatatttata tttagcagcg tcacttaatg actgtacggc
    12241 aagaattgtt ccaacagcag aaatcaggat aaaggcgatg tataaacaaa gacttgctat
    12301 cgtagcggtc atggtattct gttgttcgat ttctgaacct cttgtatgaa tataataata
    12361 gtgtccgtcg ctttctttat tttcctttgt ttcagctaat tgaagttcag cctctttttc
    12421 tagtttttcc tctaattttg ttgttgtatc ttccttagta tcaacaatta aatgccgttc
    12481 cgatatttcc aacccttgta cacattcatc tgcaacgact atggtaaatc ttccagtgtt
    12541 attcatagca tcccaatagg attttgtatc gatttccttt aaacgtaatt cattgccaga
    12601 aaattgaata ttttttatat cattattatt ttcaacttta tataacagtt cattaggagt
    12661 taccaacaaa tattcatctt tatttaattt tatagtatcc atatttctaa ttttgagcaa
    12721 tttattataa tcactcaatt tcatcactgg gtcataatta taaaattcta cggcataata
    12781 attttgtatt tgataatttg gttctttgta aatattatat tcaactgttt gatttattgt
    12841 ataatcttca tctataatac ataaaaattt atcaatattt ttgaatgtat tattctcatc
    12901 aaataaatct acatcataag gagcatttaa ttctattgtt gatttataca ttcctttgtt
    12961 aatacttgag aaattcaaac aaattaagga aattagtatt aacatcgaaa gcgtaccaaa
    13021 cgtaaagctc atggttctgg cttttgacgc aaaggttcta gcaacaaaca gattgtcttt
    13081 ttggtattta cattttttgc tttttaataa aatggataac aacatatccg aaaaagtagc
    13141 ataaatacca taaatgctga ttataagcat aatcaaacta atcattaagt atgtaattat
    13201 ttcagagccg ccaatttttt ttatgtcaaa ttgtgagttc caaagaagta gtgacacaac
    13261 tccaattata gcacttataa caaagatgat atttcttatt ttactgctat gaaacatttt
    13321 cttttcattc agtttgtcaa aatatagaaa atcatgcact gtcatttttt ttattcttct
    13381 taaaagatta agcaaaacta aaacataaat taccaaaaag taaattgcca gcaattctat
    13441 ggaagcaaag ttcatagaaa taaaaatgac ttctggaatc cccaatagtt tcacaatgac
    13501 taatgataca aactggctaa atataaatcc aagtggaatg gatagaataa atgcaaatat
    13561 tcccaataat atattttcac taacgagtaa acgtgcaatt acttttttct ttatccccaa
    13621 aagcatatat gttccaagtt ctttgcttct tttctcaaac ataaatcttg ttgtatagtt
    13681 aatcaagaaa caaacaacaa atatgataat cacattaaca aaggttagta ttgttttgaa
    13741 tgtttccatg cctgaggaca attctacaac ttcgttagaa cttgccacca gattatatgc
    13801 caatataaga gaaaatgaaa ttgtaatagt tatcagataa atcaaatagt cttttaaact
    13861 tctttttgta tttctaacag ctaatttacc taacatttcc tacttcacct ccgagcaagg
    13921 ttaatatatc cagtatttca ttgaagaaat cttttctgct tttttcccct ctgaaaattt
    13981 cattgaatat tttaccgtcc ttcaagaaca aaatacgttt acaaaaagac gcactaaacg
    14041 ggtcatgtgt taccattaaa atagtagcct gcattttctt gttgatgtca gacattgttt
    14101 ccagtaacaa tctggaagat tttgagtcca aagctcccgt cggttcatca gctaatatca
    14161 gtttcggttc attgattaag gctcttgcac aagcacaacg ctgtttttgt ccgccagaaa
    14221 cttcataagg aaatttcgat aaaatatcac gaatacccaa tttatcagcg atagcatgaa
    14281 ctcgtttgtc aatatcagca gggttctgtt tgttgattac caatgacaaa gaaatgtttt
    14341 cttcaatcgt taaggtatct aaaaggttga aatcttgaaa aatgaaccct agattttcac
    14401 gtctaaaatc agcaaaatct ttatctttga ttttggtaat atcttgattg ttgactgtaa
    14461 tgtgtccgct ggttacagta tcaatcgtag agatacagtt taatagggta gtctttccag
    14521 aaccactagc tcccattatt gcgacaaatt cgcccttgtc tacatacata gaaataccgt
    14581 ctactgcctt tgtgatattt ccagagttac ccccgtagta tttttttact tgctctaaat
    14641 ttaaaatgtg ttccattaaa aatcgctcct ttcttcctgc cacatttatt tgttttggaa
    14701 tacaattaaa ttatagcaag ggcagtgttc aattacactt acagttttga aagtaaacag
    14761 atagcaaaag agccgtgata atgcagatca caattttgtg aagcatttcc acgacccttt
    14821 tattataatt ttacctttgt cttttttgta atgatataaa tatattcttc tggtgtaggg
    14881 cgtttattcc caaaatactt tttgaaattt gcctgcacct ctgggtcggt gctattcata
    14941 gcttcatcaa tcgttgcttc aatattttcc cgtacatcag ctaatgacat accgccagcc
    15001 tttgcaccag cctttaatgc ttttttaata tctcgttttt ttaaccctat cattcgaacc
    15061 aactccctaa aatgagttaa tctt
//
LOCUS       DAEPUT010000097        15075 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.100, whole genome shotgun sequence.
ACCESSION   DAEPUT010000097 DAEPUT010000000
VERSION     DAEPUT010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15075
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.100"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(224..607)
                     /locus_tag="KRL22_003247"
                     /pseudo
     CDS             complement(224..607)
                     /locus_tag="KRL22_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      833..930
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            985..1161
                     /locus_tag="KRL22_003248"
     CDS             985..1161
                     /locus_tag="KRL22_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273692.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            1387..1587
                     /locus_tag="KRL22_003249"
     CDS             1387..1587
                     /locus_tag="KRL22_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1273693.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     repeat_region   1950..2180
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2016..2046
                     /rpt_unit_seq="actttacataccacatagttgatataaaacc"
     gene            2406..2588
                     /locus_tag="KRL22_003250"
     CDS             2406..2588
                     /locus_tag="KRL22_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBH1273694.1"
                     /translation="MFKFYNNATLMFLSGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIVF"
     gene            2659..3504
                     /locus_tag="KRL22_003251"
     CDS             2659..3504
                     /locus_tag="KRL22_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273695.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYSLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(3728..3892)
                     /locus_tag="KRL22_003252"
     CDS             complement(3728..3892)
                     /locus_tag="KRL22_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273696.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
     gene            complement(4433..4765)
                     /locus_tag="KRL22_003253"
     CDS             complement(4433..4765)
                     /locus_tag="KRL22_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBH1273697.1"
                     /translation="MNTREMKEYRVFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(5009..5650)
                     /locus_tag="KRL22_003254"
     CDS             complement(5009..5650)
                     /locus_tag="KRL22_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBH1273698.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(5631..5924)
                     /locus_tag="KRL22_003255"
     CDS             complement(5631..5924)
                     /locus_tag="KRL22_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1273699.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            6317..6376
                     /locus_tag="KRL22_003256"
     CDS             6317..6376
                     /locus_tag="KRL22_003256"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBH1273700.1"
                     /translation="MTEYIYYYNNKRIKKINLA"
     gene            complement(6892..7644)
                     /locus_tag="KRL22_003257"
     CDS             complement(6892..7644)
                     /locus_tag="KRL22_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH1273701.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(7703..9358)
                     /locus_tag="KRL22_003258"
     CDS             complement(7703..9358)
                     /locus_tag="KRL22_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273702.1"
                     /translation="MEYFSESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     YQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKQCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(10631..11710)
                     /locus_tag="KRL22_003259"
     CDS             complement(10631..11710)
                     /locus_tag="KRL22_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1273703.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIFNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            complement(11794..12450)
                     /locus_tag="KRL22_003260"
     CDS             complement(11794..12450)
                     /locus_tag="KRL22_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1273704.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            12772..12978
                     /locus_tag="KRL22_003261"
     CDS             12772..12978
                     /locus_tag="KRL22_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273705.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCLAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(13131..13559)
                     /locus_tag="KRL22_003262"
     CDS             complement(13131..13559)
                     /locus_tag="KRL22_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH1273706.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGDMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(14035..14973)
                     /locus_tag="KRL22_003263"
     CDS             complement(14035..14973)
                     /locus_tag="KRL22_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH1273707.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
BASE COUNT         5218 a         2457 c         1616 g         5784 t
ORIGIN      
        1 aatataaaag acagtaattt atctatagtg ttacttatat tttatatata tggctatttt
       61 tcaacatttt acaatatata taacatttat ttttttaact tttgtcagta aaatgtcagc
      121 aaaacacttt atccacaatt tttatataag ttttccacaa cttatcacca atattatcca
      181 cataaaaaag gtagcactta tattattagc taccttttat ttattaatct ttatatttcc
      241 agctttttat ccaacttcct atttctatta ttttttcttc agttatttct tctccatcat
      301 gtaattttga aattaattct gataaaggat tgttatgtaa acctctaaaa actctttttc
      361 cctctatttt gagatattct ctctctttta ttaatactgt atagtgtaca tgcctcccaa
      421 ttctctatga tattaaaaaa ccttttttgg ttaatctagc taaaagtata attgtagttg
      481 tatgcttcca accatatgtt ttttctattt catctgcaac atcttttgat attacagttt
      541 tataaccagt attccatatg catttcataa tttttaattc tgtatctggt aattttttat
      601 ttagcataat atattccttc tttcaattta tgtcacttct tcaaatttat ctagcttaaa
      661 ttataatagg agctttttag aacaaaaact atatttaatt tttaccaggt actctacgtg
      721 tttagtctgt ttttaagtgt aaaataatat tcatatctat aaatttattt aactttcaaa
      781 caatcctgtt gaataataac taattctatt gtattatttt agttgtagaa taaaactaaa
      841 tcggcaaaac tagagaaatt tagtgacgca aagctatagg gactaagact tatataaata
      901 tcttatgagt tatgtcagcc agttgccaaa gagatagtgt tctttttgtt tttatgaaag
      961 ttttttaggg ggataataat ttatatgttt ggaaataaaa tggataaatg tacacatgta
     1021 ttgactgctt atattagcag ttcgtatgat tattgtaatt ttttagatac acagttagat
     1081 gattttatat tagagtacgg agaaaatgta gtagagtctt gtttacacca agtaatggta
     1141 ttggtaagta agtataatta gatagacatt gatttctaga aaaccctttt tagttttatc
     1201 tacatttata ttaatatata gcaatgtaaa acgtttaaat atatttttaa tattaagaat
     1261 aattaaaatg ttaactaaaa aatataatta agtagacatt tctattaatc tatgatacaa
     1321 tagtatttgt ggtaatacac aattaaatca agtatatctt gatataggtt aataggagta
     1381 tttttaatga ataatggaat agtgaaatgg tttaataatg aaaaaggatt cggttttata
     1441 tcaatggaag gtagagatga tgtgtttgct catttctcag ctatacaaac ttcaggattt
     1501 aaatcattag aagaaggtca acaagtaagc tttgatatag ttaaaggtgc tagaggtcct
     1561 caagcagaaa atataactat attataatat atagattttt cgggaaagac tctttttaga
     1621 gtcttttttt attgttaata tatgtaagat aatcattggt gaagtaaata aggtatattg
     1681 agtaatgttc ttgatagttt atatgctaat gaatttcaaa aaaataagca ctcctataaa
     1741 aagagtgctc ttaatgtaaa tataaacctt cattggtcca gcctaatacc ccgtattctc
     1801 caagttctaa ctctttttta tatacattat cactttcagc catatctaac acaatcattt
     1861 cttctttaga atcaatttgt aaaatatgag gactgtgtgt tgtgacaatt atttgtgttt
     1921 ttgggagaat tgcttttaat gtaataaaaa ttttacatac cacatagttg atataaaact
     1981 attaagtttt ctatgtttat attcatattc aaacaacttt acataccaca tagttgatat
     2041 aaaaccttag tgtataaaca tcctttaagg tcaataggct cttgtcttta cataccacat
     2101 agttgatata aaacatgtag ttgttacttt ccagctacac tcatgctcca ctttacatac
     2161 cacatagttg atataaaacc ccaaaataaa cttagcatct ccaatgttta cacatataca
     2221 atgctcttaa aattgcagtg aacgcgcaat agtgcaattg ataatactta ttatatattc
     2281 tcaatgcctt atatttcaac tgctaaacct caatttatca caaatatcgc tcactgcaaa
     2341 atttctatat ttttattata tcataacata taattaatat tttcaattaa tttttacatt
     2401 taattatgtt taaattctat aataatgcaa ctttaatgtt tctttctgga actaatataa
     2461 aaactatttc agaaagatta ggtcatgcag atataaaaat aactatgaat agctactctc
     2521 agtttttaga agagatggac agagaagcat ttgaaaattt gagcaaaata ctatttattg
     2581 tattttaaag aagatgactt attcaatatt tgatgctaga atataattaa taaaaattta
     2641 attataggtg attgtattat gaatattatt aaaagcataa ctttactctt aacattatta
     2701 attgtgatat taatgacagg ctgttcccca agagaaagtg ctagtgaagt tgcaaaaaaa
     2761 tatattgata agatgaactc tggtgactat gaaacagcat atagtttatt aagtaaagat
     2821 agtaaaaaaa aaattagtat agaaaatctt gaagaatttc aaaatatttt agttagtaca
     2881 aaaagaataa ttagttataa aataggtaaa gaaaaaatca taaaaaaata taaacatgat
     2941 ggaaaagaat ataaaaatgt tgttaaatta gaagaaactt ttaatataaa aaaccttctt
     3001 tataaaaaag atgattctct aaaagtaaat agatattttg tagttgaaaa taacaaatac
     3061 aagctattat tgtatgaaag tttcaaaaaa gaatttggta ttaatagtat ggaccttgct
     3121 caacttaagc ttaatgattt tggactaaaa tactttaaag aagttgacct tatactaaaa
     3181 aaagctattg ctattaatcc tactgattca aagctttatt atgcccaagc atgtaattat
     3241 atgaattttg atggatttcc tggttattca gatacaacat ataatgcttt agattcaatt
     3301 aataaatctt taaagtattt agataaaaat gattctgact acaaaaaaaa tgcaagtaat
     3361 atatatagct taaaaggagt tattcttatg tttcacaaaa gatttgatga agcacaacaa
     3421 tatttaaata aagccttata ctttaacaaa gataatgaag acccaaaata taatctaaat
     3481 acaataaaaa aacatctaaa ctagatattt aatttttgaa tttataaaat atttttttat
     3541 gtataattca gcactgaatc ataatctcta ctaaactaat tacaagttta aattataaag
     3601 acttatttct atataaatat tactctataa caataagttt cttatttaaa ttttaaaata
     3661 ttatctaaaa atcataaaaa agaaggtata aagagctacc ctcaagctca atatacctta
     3721 taaatatcta aacttcattt tttactaatt tttctatatc tttgataata tgttctttag
     3781 atttttttcc agctatggca tcaaaaattg caacagcctt tttctctcca aacttttctg
     3841 ctacatcatt aaagtctaaa aatctaacac tttcttttgg tttaccaaac atataacacc
     3901 tctcatacat ttttatatat ttattataac ttctatagac ttatttttca ccaataaacg
     3961 ttagacaaat tagtcccttt atttttttaa actagcttta ccttcaaaat tcttaacaaa
     4021 aacagtttat tctactctat aaataaaaat agacaattta atttgtagga aactgataat
     4081 agaatacagt aaataaaact ttgtttaatc tatctgaaaa agttatctat taaaactgct
     4141 atgaatttat aaagaatatt ctagttcata aaaatacaaa tatgtaaata taatcacctt
     4201 aatattaatt tatttaaaat aaaaaatgta taaaagattt aataatgaca atatactatt
     4261 ctcaatacaa tctatgatgt aaataattta aaactgctat attatttaaa aatttatatt
     4321 tatatatgca attctaaaaa cttaataaga agtgaactta gaaaataaag cttaatttca
     4381 aagacttaaa tagactatta ttattagtct aaataaacta cgtctatcaa aattatatat
     4441 taaattcttc taaaattttt attgcaaatc ttgcgtttgg atatgtaata gacccgccac
     4501 caattacacc tatttttata gcttctataa tttcatcttt acttgctcca gaattaatac
     4561 aaccttcaat atgataacaa atacactcat cacatcggct taaaattgaa atagctagtc
     4621 ccattaattc cttatttttt ttacttatag ccccttctga ataagtctta tcatcaagac
     4681 ttccaaatac tctaaaaaac tcatctgttt cgcttaattt tttattgtaa aataccctat
     4741 attctttcat ttctctagta ttcatcttct acctcctatg tttttcttat aagaatatca
     4801 caccgtactt atattttcaa tattaaatac aaattttcat tttatgttca ttagcctaat
     4861 ttatattatt ttttgaaatc tcaataagtt atcatataag taagattttt tcagaactaa
     4921 aatagaaatc ttagtaattt ctttattatc tatctcagtt ctgaaatata ttattcttat
     4981 ccaaacatta ttatagtgat taattatatt agttattttt acctgaaatt ttatacatca
     5041 aataagaata tataaatggt agtattacaa ttacaaagat tacaaagata ttataaaaag
     5101 gaatattaat aaatgcatta ataattaata atattccacc aataagccaa atccatccag
     5161 ctaaatggtg tgtcttattc caattatctt catcattaag agtccatggt aaaattattc
     5221 ctactgagta atttcgttta catttaggaa gatagtttcc aaataaaata actattattc
     5281 ctaaaattaa tcctgtataa aaattagact ccaaactaac tcctgttgaa tataaaacca
     5341 tcattatttg tataattact gaaagtatag caactcccca ttttgataaa ttttgtataa
     5401 catttgaaaa attagctttc ttaggctcat tctcaagtct aaaccatgta tacaaatgga
     5461 tacatagcat taacaatggt acaccaaaag ctgctataac ctttggagca taattatctg
     5521 gatttccata attatcaaaa tgaattgcaa cttcatttgg taatctatta taaaaatata
     5581 ttgatacaat aaatggtata aaacatatta aagtagataa aataaattgt ttatttatcg
     5641 cttttttcat tatctttttc tcccttctcc ataaattgtg aaaaccaaag catgacctct
     5701 tcgaaaactg aaatatttat ttcgtagaaa ataaagttct tatactttgt ttcaaatatg
     5761 agtcctgcct tttttagttg agatagatga taagaaattg tagcattcgt catattaaat
     5821 ttttcactaa tttctcctgc tgacatttta ttctccctca acataaccaa tatttctctt
     5881 cttatagggt ctgaaagagc tttgaatgtt tctggaaacc ccaacaccat cacctcgcta
     5941 tttagaattt catctaaata gaatataaca taacatccat tttatttcaa tagctattta
     6001 gaaatttttc taaatagtta tttctaaata tttattgaaa atttttatat taagattctc
     6061 aatttactta agtcgctttt atttaatctt actttatcta atttttttaa cttaacaaaa
     6121 gtgtattgca ccataattgt taaagcaaaa acctaatgat tgaggtactt atatatataa
     6181 caatactttt aattttaaat taaaagtagc taaacccaat ttaaaaagta gttaagtcct
     6241 atttaaatag aaaagaatga aacgagaaat atactgtata aaagtacata aaaacatcta
     6301 ctaattagat acaactataa cagaatatat ttattattat aataacaaaa gaataaaaaa
     6361 aattaattta gcataacctt gttaaatata gatttgaata tgaatttaaa gttatgtaaa
     6421 attaaaaata caggaatgaa aattccattc ctgtataaaa tctaactttt gagtctcagt
     6481 acaatcttat tttgagacaa tcttttttgt tttatatttt cttatattta aaatataacg
     6541 catatcttat gcaacatatt catatttttc tttatattct ttcatcgcat cattccaagc
     6601 gtcttgtact gttacacctc ttttattagc aattttttgt gccagttcaa ttatcttcat
     6661 agctcttctt gatatgttca taaacattcc tcctacaaat taccatatat ttcatatata
     6721 taaatcaagg ttatattttt atgatatata atccttctat tgtaagatta cagtttatat
     6781 gtgtattata tatgaactat attagaagat aattagaatt tttataaagc tatatgatta
     6841 gattaaatat aaaagcttta caattactta taaatttaaa aagtctataa gctaaactaa
     6901 tgtttgatat accaatttta cgaccataaa taatgccatt actaaaaata ttggttttat
     6961 catctttgaa cctttcttta tagcaacttt agcacctaca taagctccca ttatcatcac
     7021 taatgcaaac actatagcaa ttttataatc tacttgacca tttatcatga ataataacaa
     7081 tgaagttata ttacttgtta agtttaatat ttttgtattt gcagaagcat gtaaaaaatc
     7141 atatccatat atttttataa atccaaaagt caaaaaagtt cctgtacctg gaccaaaaaa
     7201 accatcataa aaacccatta taagagccat aagcatccct aatcttaaat ttttcttatt
     7261 aacagcttca aaattatctt cttgacctaa atttttagaa ataaaggtgt aaatagccac
     7321 tattaaaatc ataaccacaa ccaaaacatt taatatctct tcacttattg ataatacaca
     7381 tctcacacct agaacactac caataatagt aaatggtact aattttttta aaaggttgtt
     7441 attaattttt ccagactttg catatctata ggcactactt atacatcctg ctgatgctgc
     7501 aaatttattt gtaccaatgg caagatgtac tggcactcca attgccataa gaacaggcat
     7561 gcttataagt cctcctcctc ctgctataga atctacaaaa gcagctaaaa acccccctat
     7621 acataaaaaa ataactgaaa acataaaatt cctccatcat tctctttcaa tttttcttac
     7681 aatatatatt atataatctt atttaatact tattatccag catattcttt ctatattcat
     7741 ttggagttat actattaaac ttcttaaata tttgtgaaaa ataactactg ttattaaaac
     7801 ctactttctt acaaatatca ctaatactca tgcttctatc taacagatat tttttagatt
     7861 cttctatcct aagaagattt atatactcag ttattgaaac tttatttctt tcattaaaaa
     7921 tagaactcaa ataatttgga cttataaaaa aaacatctga tatactattc aaatttatat
     7981 tttctttata atattttttt atatattcgt ttatattttc aattagattt cctttatctt
     8041 ttctccaaaa tgctctattc ttatcaatac actctttgga aaattcaaat aatacattcc
     8101 ataaatcttc atcactgttt acaagtgata tttttttatt atatttattt cttaaataag
     8161 atataagttt taaatcctct aaatctctaa gcactgttct agacaataca aatatcattt
     8221 cctgaatagt atctctaaca tcattatatc ttaatttgtt tgtatctatt agattataaa
     8281 caccttctaa attcatattt ttaatttctt tttcaatata aagttctaat tcaaagggat
     8341 attcttttga agaattattg aacatatcta tcggattaat aatatactct tcttctaata
     8401 atctactatt tgctttttta agtgcctctt caagtcttat attttctttt ctactcttca
     8461 atatctcctc atcttttata ctaagttgat tttcaaaaaa attcctctta gctatttcct
     8521 gaataaattc agacatcatt aataaatttt cttttaatac atataatcta cttttaggat
     8581 ttaatggaaa ttcattgtaa attttgttta tgtattttat atcaatacca gaactacttg
     8641 ataattcaga taaattttta tctatatcaa tagacttata tactataaaa ttaccacatt
     8701 ctatatatcc aactatattt tcttctaata ctataggtat ctctaaactg gaaacaccat
     8761 actcacaatg gtacactttt tcaaagttat cattatttat gcttttaaca agttttttag
     8821 tacactgttt tatattttta caaatatcgc aaaatttatt ttctttctta gtctcaaata
     8881 tttctttata ctttaagtca tatacagata ttctaagctt caatatatta gatatttgat
     8941 ttgcaagatt ttcaattatg tttacattaa ctaactcctg tatattgttt tcagaaaata
     9001 ctataggtat ttgtctcaaa ctcgaaaatt tatgaggaac ataagtaatt aatattacta
     9061 aatcaatttt accagtgttt ataatttcat gttctgaata tggtgggcaa taaactatag
     9121 atgtttcctt tatattgacc tttttaccat caattatttg tattccttct ccctgaatca
     9181 catataaaag ctgttcttca cttaaatgaa aatgcttttc ttggtagttt cccggaaaaa
     9241 atcttacaat tccagcacta agtctattga attgtgtttt tgatggttcg tgtatccaca
     9301 taacctctcc ccaatcaaat ttttgtactt cattatttga ctcactaaaa tactccataa
     9361 gctcacctct tagtttttgt ctaaatattt tttcttccct tcttatatta aaataatatc
     9421 atcatcatta actttcatta ctataaaatc atcatactct tttaatactc ctgtaatttt
     9481 agttgcactt agtttactac aattcagttt tttaatatat tgataaattc tataattact
     9541 tttttatttt gtaaaatcag tgttttccca aaataattat atctataaat gaaagtattt
     9601 ttactgctta catcaatata tgttatcata attttccttt ttattgcata tataaataac
     9661 tgtatataac attgtccaat actatataga aatacatcta agaaagaata ttattaaatt
     9721 gttccaatta gtattatttt tcttatagaa ataaaaaaac tgttggagtc ttttagaaaa
     9781 attatttttt acataccttt tttgcttaga tagtctatct tcacagctat tttgtatata
     9841 cactcttcta gttcatgatt ttattttaat atcttgctta tattgctgaa ataattgaat
     9901 tcttttatct atcatattgt ctcttatatc acaaacatat tgtttcttat atcacaaaaa
     9961 tgaaagcatt cttatatctt caatatataa acctgctttt tttaatcttg taataaatat
    10021 aggatactct atattctctt cctagaaata actaatacca cttatttttc tattatatag
    10081 aaagtaataa atctttttct taataaaatt caatagtaag tggaataaaa ttttatatga
    10141 ataagaacat tataaaaata ctttatacaa tagtcaataa aagatattag cttcaaatta
    10201 tgttaaagtt gtattattta aagtgaaaaa acaaataaaa aagaaataat agtataagta
    10261 gaaaaatata cttaaaacaa ggcgaagcct ctcttgtatc taaatcaagt agagaattaa
    10321 atctaaaaaa gaaaataaat ataaaagatg actcctgtac attacaagaa tcatcttatg
    10381 gtttcataat cactccatgg tttttaactg tctgatataa aggtctcagt tcactcatag
    10441 catgaccacc ttttccgatt gctgaccccg tcacttatgg acaaaatgtc cataagtgat
    10501 agtcctctct taaaaccctc taaatagata tatctcaagc accgcattga aaccagttgc
    10561 tggaaacaaa ctgaagcgtt ctggaatagt aaaagaaatt gccaccatat ccacgttact
    10621 gtcctagttg ttactttgct aacttcggag cgatttcctc taacaatacg cagtcaaatt
    10681 ctgccttttt gctaagaaat ggcagatggt ctgcatctgg tataaaaaaa atctgtttgt
    10741 ctggcgccac tatttcatca aaaaatttct tcgctggaag ataggggcta ttatagtcat
    10801 tttctcccat gatgtagtat acagggacct gatagtcaac tccataattt cttatgtcag
    10861 cttcttccac taaaaaccgc aatacatcac cttgattgtc aatcgcattt ggattgaaaa
    10921 tggccgtatt ttttaactct ctcaatgaat aatacggggt tgccagtata ctgattatat
    10981 tgcccaaatc catatttata gaaagcccat acttgctttg gtatgttctt actgtcataa
    11041 gagctgccaa atagcttgga ccatattttg ctggcggata tggtgcaata gcttccagcg
    11101 ccttgatatc tttttgcttc cctgcagctt tcaccatttc aagtgtcttt tcatagccca
    11161 cgcgctcatt gtccaccata ttaacggtct gcgcaatccc aatgtacgcg ctgtaatcct
    11221 ccggataggt ttgcacagcc atagttccca gaactgttcc ccagctatga cctataagga
    11281 taattttctc cttgttgaac tcttgcttca aatatgctgt cacctcatgg acgtcttgca
    11341 gaacacgctc cgcgctcatg gtctgcaaaa ctgctgccgg atcgttcgca aagtatgttt
    11401 tgcctacgtt tcgctgatcc cagttcacca cagtaaaatc attttcccac tcatactggt
    11461 acagatgtaa aaatggcatc attgaattac caggaccccc atgaacccaa aggatgatgg
    11521 ggttgtctgc gttttgtccc cggatatata acgcctgctg tatgccgccg atctccacca
    11581 tttccatgcg gtcgattcca ggagcttcta ttttatggct tgtacgtata atcgtggggg
    11641 ctatcagacg caaaccggca aacgccagaa caaaaacagc aactagtatg caaagtgtga
    11701 ttaatatcat tttaagtacc ttctttcatg aattttttta gccatagata tctcctctaa
    11761 cattaaaaaa aatatgttgc tattttagtt ttgttactct acctgtccca ttggtttcct
    11821 ttcataaaaa atattaattg attctataat ctcatcttcc aggatatcaa ctcctatttg
    11881 tctcataaga aactgtaaga attgaaaccg tttacgaagt gtaggaaagt ccccctgaaa
    11941 tacatctgta tcacaccaaa agttaaagag cagcaaaatt acctctgcgc attcatctgg
    12001 gaactctgtg atgatgcttc tatcctctat gccttctcgt aaaacatttg ctaatattgg
    12061 tgctagtttt ttcaaattat cctgtgtaaa tgccagtatg atatgcggac tttctatcgc
    12121 gcttgtaatc atgttactag attcttttat cacctcatcc gttaaatgcc gcctaactaa
    12181 acttctaagc ttctcttttg ctgtaagtcc atgcatttca ccgagccatt gatttactgt
    12241 ctctattatc tgttcaaagc gcctttccat gaccacatta aaaatatctt cttttgaact
    12301 gaagtgatga aaaattccgc cctttgacat tcctgaagca tcaacaatat tttgcatact
    12361 tgttttgtca tatccttttt cagcaaacaa ctttgcagaa atggtaatga tattttcaat
    12421 agcttgcttt ggattgttct ttctagtcat tatataactc cttcttatta aaaaccgact
    12481 gttggttttt attatataag ctattcctgc ttctgtcaag taacattgtg tttatggcaa
    12541 aacaataagg tttggtggtt agacaggtat taattagact aatgcgactt tcccctagat
    12601 ggaacccttg gtaaatttgc aatctttacc ggctttgatt atatctgtaa gcaaggcagg
    12661 tatggccaca cctgccctgt ttgcccctcg gatattcatt cctatccctc ctctccttag
    12721 ccattacacc aaaacgccgc tcattgtctc caatggcggc gttttaaaga tatgatttct
    12781 catgctgctg aaatatgcaa aaaatataag atgcccttta ttatttttcc tacaatagaa
    12841 aagaaaagta ttgaagaatg ggttaatatt ggagcaaata tgctttgttt ggcacaagat
    12901 actaccttta tcacttatgt tatcaatcaa ttattatctt tttataatga gattgtacca
    12961 attcaaaaac aacattaaat tataaatcta attttatatt aaaagagact aatattttat
    13021 ctatctctat taaggatatt ttcttatgta tcataatatt agtctctctt attattatat
    13081 actgctatca tcattagttg ctatttatac tatttttata atatacaaat ttattcagct
    13141 aacgttttgc ctaattctat acactcatct tttgcttctt catttgggtc ttccattgct
    13201 gtaattcctt ctccaccaat aattgtagca ccagcatttt gcatacgttc ttcccaatct
    13261 ctcatccatt cacaatttcc ccatccatat gaaccaaata atccaatctg tttacctgat
    13321 accatagatt ctaattctga aacaaatggc tccatatccc cctcttctag ttgctctgct
    13381 cccatagatg ggcaacctaa tgcaaattta tcttcttctt ttaaatcact tggtttcagt
    13441 aagctcacat ctaaaacttc tggtgtctta ccttttaact tcacaccttc agccacaaaa
    13501 tttgccattt tttcagtatt tcctgttcca ctccaataaa caatatatat tttactcatt
    13561 tttacctcct gtagtatttt ttaattaatc aatagttagt tatagctaac taacatctaa
    13621 aaaacaaaag atttctttat ctgaaatctc tttatttttc taaatataga atatcacaat
    13681 tgattttgaa attcaatact tattgataac atttatcatt tatgctttat attcatttta
    13741 taatatcaaa acactgtatc gtatttctaa tctttcatag aaaaatttct aacttatagt
    13801 acttttgcat ctcttataaa tcttttatat gtataagtac atagaaaaac acaccttttc
    13861 cagatgtgct atctataata tcgtatattt atttttcaat tctaactagc taatatgttt
    13921 ataaatttta tcacttaata cctttataca ttgatgtaaa atcttacacc taagtaattt
    13981 ttattatttg tctcgactct atataatata gctattttat catcaaatca aaaattatct
    14041 tttgctatta ttcttgtatt tataaagatt taaatataag tatccatttc cttgttccgt
    14101 tctaggtatt ccaagcgctc tcgtacattt tattaattgt gcatacagtt cagcttcatc
    14161 taaatctctt tcaaactcct ctcttgccca ttctttaatt agtgctaatg agcctgatac
    14221 gtatggtgca ctcatactag taccactcat aatagcaagt ttattatcca tataagtcga
    14281 tataatattt cttcctggag ccaccaaatc tattgtagta tttgaattac taaacttttc
    14341 aaccaaatag ttttcattta ttgcacctac ttctattacc tcagcataac tggctggata
    14401 actatactca cttgtactag aatcaccatc tccattatta cctgctgcac acactacaga
    14461 aatattattt tttactgctt gcatgacagc attttttaaa ttcttatcat ctttgtttcc
    14521 cccaagagac atagatataa tatcaacctt gttatttaca gcaaagttaa tagcattaat
    14581 tatactttga tatgttccgg taccatcttt atttaatgct tttgctatta ataatttaca
    14641 atctggagct actcccataa cttcattatt ataattagat gcagctataa tacccgccac
    14701 atgagttcca tgaccattaa aatcctcata tatattttta tttccattac tgtcatcact
    14761 aaaatttgca ccaccaatta tttttccttt taaaagagga tgagatatat cacaacctgt
    14821 atctattata ccaactacaa tatttttgcc agtataacct tcatcccaca ttcccctagc
    14881 attcatttgt tttattccat atgggaattt attttttgca cctcttagat tttcatttat
    14941 ttcatatgga attagtttca ttcttttatt catcatatat cctcctaaaa attttattgc
    15001 ttataaaaat catgaatttt attttataat aggtttataa atcaaattaa aacctatatc
    15061 tacttattta tattt
//
LOCUS       DAEPUT010000098        14936 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.101, whole genome shotgun sequence.
ACCESSION   DAEPUT010000098 DAEPUT010000000
VERSION     DAEPUT010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14936
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.101"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            540..3182
                     /gene="adhE"
                     /locus_tag="KRL22_003264"
                     /gene_synonym="adhC"
     CDS             540..3182
                     /gene="adhE"
                     /locus_tag="KRL22_003264"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH1273708.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
     gene            complement(3543..3884)
                     /locus_tag="KRL22_003265"
     CDS             complement(3543..3884)
                     /locus_tag="KRL22_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273709.1"
                     /translation="MLLILGNLNLDLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIVNIKNQN
                     EKVILNKSIKK"
     gene            complement(3919..4587)
                     /locus_tag="KRL22_003266"
     CDS             complement(3919..4587)
                     /locus_tag="KRL22_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273710.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVAGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIEDLINLLGLKERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRVISIIDGE
                     LKLN"
     gene            complement(4599..7175)
                     /locus_tag="KRL22_003267"
     CDS             complement(4599..7175)
                     /locus_tag="KRL22_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1273711.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YANKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKMGQCEIFSNLNESKLSDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFMIIVLSMSIGGIIVIKDNYKYSFLDVQNKSVQEQTYM
                     NADFILSNVYLNETGNNTSFKDIKGFSDSQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NKLDYYEAINSKPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYTFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLIYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISEREFKNMILYEGILYGVLSSIITIVSGLI
                     IQLKMYYMQGFISHGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            7383..8318
                     /locus_tag="KRL22_003268"
     CDS             7383..8318
                     /locus_tag="KRL22_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1273712.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFFVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            8337..9074
                     /locus_tag="KRL22_003269"
     CDS             8337..9074
                     /locus_tag="KRL22_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1273713.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKCLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(9259..14316)
                     /locus_tag="KRL22_003270"
     CDS             complement(9259..14316)
                     /locus_tag="KRL22_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBH1273714.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNTQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLVLLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDHSILSNL"
     gene            complement(14341..14760)
                     /locus_tag="KRL22_003271"
     CDS             complement(14341..14760)
                     /locus_tag="KRL22_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273715.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
BASE COUNT         5198 a         2110 c         2124 g         5504 t
ORIGIN      
        1 tataaaaatt atttatctat atgaaaagca taattattac atattgactt aaaaataact
       61 tatagagatt agaataattt tagtttatat attttttaaa actatacagt tgttataaaa
      121 agaaaaattg catacaagtc aaaaataagt gttattttat aaaaatacga caaaaatttt
      181 atttactact tatacaaata acatgcaaat aacatataaa atttaataag taaaaaaaat
      241 gaaagatata aattatcatt ttagtatttt atttagtcga agtaaattat tcaaatgaaa
      301 tatatctcat ttagataaaa aattttagta aaagtaaaaa aaataatata tttgttaaaa
      361 aataaattga caaaatattc agaaaaaaac ttcttgacct aagagagtaa aataaataaa
      421 atctaaggta tagagatgaa atctataaaa ttattttaag tataagttaa aaatatagat
      481 gatgcattta agatttataa aaattagaga tgcataatta ttttagggag gtttttagta
      541 tggagaaaaa agaaaaggta gtagaaaaat caaatgttga agtatgtagt cctgaaattg
      601 tcaacagtgt tgaaacatta agaatgagat tagaagaaat tagattggca caaaaagaat
      661 ttgcaacatt tacgcaagaa caggtagata agattttctt agctgcttca actgcagcta
      721 atcaacaaag aatacctcta gcaaaaatgg cagtggaaga gactggtatg ggtattgttg
      781 aagataaggt tataaaaaac cattttgcct cagaatatat ctataatgct tataaagata
      841 ctaaaacttg tggtgtcata gaaaaagatg aagcatttgg ttttacaaga attgctgagc
      901 cagtaggtgt tttatcagca gttataccaa caactaatcc tacatcaact gcaatattca
      961 aatccctaat agcactaaaa actagaaatg gtataatttt ctctcctcat ccaagagcta
     1021 aaaactgtac tatagaagca gctagagttg tacatgatgc agcagttaag gcaggagcac
     1081 caaaaggact tataggttgg gtagatgttc cttcgattga attaactaat gttgtcatgg
     1141 cagaggcaga ccttatatta gctactggtg gacctggaat ggttaaatct gcatactctt
     1201 caggtaaacc agctgtcgga gttgggcctg gaaatgtacc tgcaataata gatgagagtg
     1261 cagatataaa aatggctgta agttcaatct tagtatcaaa atcattcgat aatggtatga
     1321 tatgtgcttc cgagcaagct gtaatagtac cagaaaaaat atatgaagaa gttaaaaaag
     1381 aatttaaata tcgtggagca catttcctaa ataaagaaga aactgaaaaa gtaggaaaag
     1441 tagtaataat tgatggttca ttaaatgcca gaatagttgg acaaccagca catgtaatag
     1501 ccaaaatggc ggatgtagaa gttccaaaaa cagctagaat aataattggt gaagtagaat
     1561 ctgttgaatt aaatgaacct tttgcacatg aaaaactttc tcctgtactt gcaatgtaca
     1621 agtctaaaag ttttgaagat gcagttgcta aagcagaaaa attagttgca gatggaggct
     1681 atggtcatac atcttcatta tatgcagact ctataaatca tccagagaga gtagaaaagt
     1741 ttgtaaatgc tatgaagact tgtagagtat tagttaatac tccatcatca caaggtggta
     1801 taggtgattt atataacttt aaattggcac cgtctcttac tcttggttgt ggttcttggg
     1861 gtggaaactc agtatctgaa aacgttggag taaaacattt gcttaatatc aagacagtag
     1921 ctgaaaggag agagaatatg ctttggttca gagcaccaga aaaggtttat ttcaaaaaag
     1981 gatgtttagg tgtagcagca agagaattta aggatgttat ggataaaaag aaagcattta
     2041 tagtaacaga ttctttccta tataataatg gatatactaa gaaattaact gatttattag
     2101 atgagatggg aattaagcat actacattct ttgatgtagc tccagaccca acattagctt
     2161 gtgcaagaga aggagctaaa gctatggctg atttccaacc agatttaata atagctgtag
     2221 gtggaggaag tgcaatggat gctggtaaga taatgtgggt aatgtatgag catccagaag
     2281 tagatttcca agacttagct atgagattta tggatataag aaaaagagta tatgtatttc
     2341 ctaagatggg tgaaaaagcg tattttgctg ctatcccaac ttcagcagga actggttcag
     2401 aagtaactcc atttgcagtt ataactgacc aagattcagg tgtaaagtac ccattagcag
     2461 attatgaatt aatgccaaac atggctataa ttgatgctga tatgatgatg gagatgccac
     2521 caagattaac agcagcatca ggtgttgatg ctttaacaca tgcattagaa gcatatgtat
     2581 ctatgttaag aactgaacca gctgacggtc tagcactaca agcaggtaaa ataatatttg
     2641 aatatttacc tcgtgcatat aaaaatggaa agaatgataa agaagcaaga gaaaaaatgg
     2701 caatggcatc tactatggca ggaatgtctt ttgcaaatgc cttcttagga atatgtcact
     2761 ctttagcaca taaattaggt gcattccacc atgttcaaca cggtgttgca aatgcattat
     2821 taataaatga agtaatcaag ttcaattgtg cagaagctcc aaataaaatg ggtgcattct
     2881 cacaatacag atatcctgat tgcatacaaa gatatgctga atttgcttct tttgcaggta
     2941 ttaaaggaag tacagaccaa gaaaaagtag ataatcttat aaaagcaata gatgaactaa
     3001 aggcaaaagt aggtcttcct aagactataa aagaggctgg agtagaagaa tctaaattct
     3061 tagaaagatt ggatgctatg gttgaacaag cttttgatga ccaatgtaca ggtgctaatc
     3121 ctagataccc attgatgagt gaattaaaag agatatatct aaaagtttat tatggtaaat
     3181 aatatctatt gtgcaacata ggttctattg ggtttgtata taaattatta gatttgaata
     3241 taaatagagt tttattagag acacgtagaa gtaactataa ataatagatt ataatttaaa
     3301 ttctaaatgg aaatgataaa aagtcagtaa tttaatggta atttcgaata tgtgtattta
     3361 atcaattaac tttaaaatta gtcggaaaat ttttttatta catataattt taaagcaaaa
     3421 tatataaaaa actttatgaa aaaattataa aaatattcag aaaattctat tgactaattt
     3481 atttatcatg atataataag tttagaaaag aaaaagaatt ggggcctatt aaggccccct
     3541 tactattttt tgatagattt atttaaaatt actttctcat tttgattttt tatatttact
     3601 atagagtcag tataatccac ttcaaagttg gcaaaagcag agaataaatc tatatctctt
     3661 aacaaatgaa ttgtcataca ttgattgttc ttatttagcc ttagaatcaa tgctcttaca
     3721 aatggaaatt gtattctaga attaaataag ttagaaccat cagtatctat atctaagcta
     3781 cgataattaa tatctataaa tatatctaca tcatcatttt cttctcttat tattctgtag
     3841 tcgaaatcca agtctaaatt taaattacct aaaatcaata acatttaaat cctcttttct
     3901 ataaatagtt ttagagtgtt agtttaactt aagctctcca tctattatag atataactct
     3961 gtctgctttt ctagcaatat tttcattatg tgttattatt ataagggttt ggttatattt
     4021 ttttatagaa ctttttagta aatccatgac ttcttctgta gttttactgt ctaaatttcc
     4081 tgttggttca tctgctagga ttatacttgg ttttgcagat aaagcacgtg caatagcaac
     4141 tctttgctgt tgaccaccag ataattggtt gggaagatga tttttccttt ccttaagccc
     4201 caataaattt ataaggtctt caatatattc tttatctatt tttttattgt ctaactttag
     4261 tggtaattct atattttcct ttacatttaa tacaggaatt aagttatact gttgaaagac
     4321 aaatcctact ttttgtcttc tatatcttgc tagttcttta tctgaaaggc aacatatatc
     4381 tttaccagca acttttatag taccattact tggtctctca agaccaccta ctaaatgtag
     4441 aaatgtactt ttcccacttc cacttggccc aattattgca acaaattcac ctttatttat
     4501 ttttaaattt gcattcttta gtgcatgtac agatgtttcc tttttcccat aaatcttacc
     4561 taaattaata gtttccaata taggcataat tatccctcct attctgtaat gtttatagct
     4621 tcaactatac taattttatt tatctttctt gatggaatat atgtagctag aatacctaca
     4681 attatatttg ctacaacaac tagtatatat attttgtaat ctattgaaaa tcccaatcca
     4741 tgtgatataa agccctgcat ataatacatt ttaagttgta ttataagtcc tgacacgata
     4801 gtaattatac ttgagagtac accatataat attccttcat aaagtatcat atttttaaat
     4861 tctctctcag agataccaat agctcttaac attccaaatt cactagttct tgaagttaag
     4921 ttataactta tgttgtttat tatgttaagt acactgatta tgaacattat tgctactatg
     4981 ccataactat aaatcatagt tctagatgtc atcttatcag aattttcttt ttctaccatc
     5041 atatctactg ttgtagttcc aggaacttca cttccaattt tacctaaaag gttatttatt
     5101 tttttcttgt ttgcattttc attaaggtct gcataaatta agttatattt atctacacca
     5161 gttaattttt ttaggtattc gctacttgtt attacatcta caccatcatc tccagagtac
     5221 ataccattat ctgcaaaagt ataacttata atagctccaa ctttaaattc atattctaag
     5281 tattcataat tatcttttag actttcataa agccctgtat ccatcccacc ctttggatat
     5341 ttgactttta tagtatcacc tacttttata tctacagctg gtgtcccttc accaggagta
     5401 aaagtctttg tgtatttctg tgttttagaa atttctggta catatacaat agctaaattt
     5461 tcttttttca tttttttcaa gtttatattt ccacttacta agtatttttc taatgacttt
     5521 atcatctcat cattataacc ttttagcttt tgctttagtg tatatttgcc agtagtctta
     5581 ttttttatga acagaggatt tagtttataa taaggttttg aattaatagc ttcgtagtaa
     5641 tctaatttat ttattttatt tacctctatt cttgtgttta agatactagc agttttgact
     5701 ttgtcaattc catctatatt ttttatttta tctatctgac tatcactaaa cccttttata
     5761 tctttaaaag aagtattgtt accagtttca ttgagataaa catttgatag aataaaatct
     5821 gcattcatat atgtttgttc ttgcacggat ttgttttgca catctaaaaa agaatattta
     5881 taattgtctt ttatgacgat tatacctcct atactcatag ataatacaat tatcatgaac
     5941 ccctttttat ttctaaagat gtttttcgca gatatagatt ttgttactga catatttaaa
     6001 gttaattttg atattaaata attaactttg gttacatttt tatcagctcc aaaagttttt
     6061 ctgatagcat caataggaga aattcttctt atttttaagt atgtaaagaa acttataatt
     6121 agtattatta gtattgtaca tgcaattgat aagagaatta ttttatctgg aataacaaaa
     6181 ggtgtaacat ttatatttcc ttcaaattga atatttccta cagacctatt aaatatttgt
     6241 gcacctccca tacctataca tatacctata ggcattgcta ttagagcaag tatgaaaagt
     6301 tcataaagca taagtttgaa aatcctaaag ttggtggaac caatagctct taagacgcca
     6361 tattcctgta ctctttggta tattgatata acatagatac tatatattac aataccagca
     6421 aatagactca tagcaattgc aacgtattta cttgaattat ctaaagtacc gtttttcata
     6481 gtagattcta taagcattga gtttcttcct atacttttct catctaacat agcatttttt
     6541 attatattgt ctatgtttgt atttatatca ctgccttcat taaattcaat ataagttgta
     6601 aaatcactta gttttgattc attgagatta gaaaaaattt cacattgtcc catttttttc
     6661 tctataaatc tatcttcaag gattccaaca actttaaaag tttctggatt ttctttttga
     6721 tataatttaa aagtaaggtt ttgatttatc tctggtttta agcccatact atttaaaatc
     6781 catttctcga ctaccacctc attgctagct tttggaaatc gaccttttat aagtttagaa
     6841 tgactagtca aataattttt atttgcatat agtatgttta taggtaattt ttcattaaca
     6901 tctgtagacg catagtaaga tgttataccc agatttttaa tatctttgct agattttatg
     6961 gactttaatt gatttttctt tatattttta aagtatacat ggtcagttcc aagctctctt
     7021 ttcaatctat ctacatctgc ttgctgagca cttcttgaga gggtaccaat accaacaacg
     7081 agtgatgtag caagaattat actcacaaca attgctaaag acctagcttt ataacttttt
     7141 atatacctta gtactatttt caaattatct ttcatattta ccacttcctt tcttaactaa
     7201 atcaattata tatttatcta aaatatatag caaagtaagt attttcaagt tttaagtagt
     7261 taattgtaca aattcatctg tatttttaca agtttaatta atctatatgt aaattttaac
     7321 tttttacata atttttttaa aatgatataa tccctatata aattgtagag gggaggggaa
     7381 tcatggataa caattttgtg tttcctatag taatactaac tttgtttata tttagcaatc
     7441 ttataatgaa taagtataaa ttttacaaag aattagacat attaaaaaga ggcatattaa
     7501 cattttttat atcgtgtttt gcattgattt tatttatgga gggcactaaa tatatacaat
     7561 taaggttagg atatagtttt ttacttgaag gagtattaaa tattatactt ttttttgttt
     7621 taattatttt aagtttttat acaggcttta aagttataag attgataaat aataataatg
     7681 aacaggaata taaactacaa aaactagata gtaaaataaa tcataaggat aatataatta
     7741 tcaaattaag aagtcaaaaa catgactatt tgaaacattt gcaagtagtg tattctctat
     7801 taaatactgg gctagatgaa gatgccaaag aatatataat gaatatatca aatagcttta
     7861 aatcaaaaaa ttcaaggtat ggaaaagtat cttatttaga tgctatagct tcattaaaat
     7921 acgaggaatg tcttgaaaag gatatatctt ttgatgtcta cattcaagat tttatggata
     7981 atttagagat tgaacctaat gatatgagtt cagtactatt aaacataata gataatgcaa
     8041 tagagtcttt gtctactata aaaaaagaaa agaagtatat aagattacat gcatatgaag
     8101 atgaatttca gtatattata gctataaaaa ataatggtcc taaaatacat aatgttgaaa
     8161 gtatattttg gaatggattt agtactaaag aaggacaaga taggggatat gggctacatt
     8221 tagttaaaaa tatattagat aagtatgatt atagtatact tgtaaatagt gatgattttt
     8281 taactgaatt tgtaatctta atcccaaaat attattagtt aggaggagaa aagtctatga
     8341 taaaagtttt gatttgtgat gatgataaga ttgtaagaga tgatatagca aatatagcta
     8401 aagagtctgg atatgtagat tatgttaaaa aagttaagga tggtatagag gcaattgaat
     8461 ttataaaaaa tgagaaaata gatttattga ttattgacat tgatatgcca tataaaaatg
     8521 ggattgattc tgctgaagaa attctttcta tagataagga tatacatata gtatttgtga
     8581 cgggtttcgc tgattatagt cttgaaagct ttaaagtgca tcctatagat tttgtagtta
     8641 aaccatttaa aaaagaaaaa atacttgatt caattaacat agcaatagac catattaact
     8701 cccataagat tgctaataat aattttatag aagacactct ttttgtatat aaaataagga
     8761 agcagataca tatgattaat tttgatgata tagttatgtt tgagaaaaat tcaagagcaa
     8821 ttaatctaca cactaaagat gaagatataa taaagtttta tgagaacttt gatgatttaa
     8881 aaaaatgcct acctcctaat ttctttatga cccatagaca atacatagta aatctaagat
     8941 ttatacataa ggttatacct ataaataaat cttcattaga gataaggttt ataaattttc
     9001 aagaaaatgc catattaaac aaatctctag aaaaagattt tttatataga ttttataggg
     9061 ttaaaagatt ctagtgaaga tagaagaaaa atactttttg tgtgatataa taagtaccgt
     9121 aaagataatg tataagagaa gtttatataa aaattatttg taattatgat ttaatctata
     9181 taaattacag tatagtatat attggacttt ctaatttttt taagaaagtc caatatattt
     9241 tagggatagt ttttatactt ataaattact taagatacta tggtctttaa tcttactatc
     9301 ttcagcaagt aatagtatct tagacataat ctcagcagtt ttagggtctt catcagcgaa
     9361 tggaaggaat atcttacctc tactttgaga atgtatagga agtatattca aagcacccat
     9421 ccctttttta tgtacaatac cagaacccat atgcacagaa tactcaccta aattacctgc
     9481 tataagagca tgagagcctt caaaattgac attgttaatt tttaataata ataaaagttc
     9541 tttagcaatt gctatacgca tctctacagt agaatggcta gtttcagggt caacaccacc
     9601 agcatgagcg acacttacaa caaggtctat atcacgcata acttctgaga atagaattgg
     9661 aggtatagaa gctaattcta aacttttata agtttttcta tcaaaaaatt ctactgtttc
     9721 aatagtagga ggctctatat ctgctggtga aaaccaatct gcaagtgcaa acatctttgc
     9781 cactatattt tctttataaa atactttctg taatccctct tcataatcga cagtccaaag
     9841 ctgatttcta agaagtgcta cagttttctt tggctgaatt tggtgaccag catatctgcg
     9901 agatatagtt ttttcagata attcatcact gtttattcta taatactcac ggaatacttg
     9961 cttaaatggt tgaacaattt gcttactaaa taaatcatgt tggaactcac tccacttacc
    10021 agattcaaac aaatgaactg gatgtgcaag ttttaattta ttttttgccg tcaacttata
    10081 agtttcacct tctatattgc aaataaagaa cttagactta tcattataaa catatccaat
    10141 attatcatca catacccata ctagattttt aatcaaaggg cagataactg gatttttata
    10201 gatattggca atttctttaa ctgtaaatac tatttcattt ttcatagctt gttctaaact
    10261 ctgttttgca cgagaatact gactctttaa atctttttgg acagatttaa gttcaagtac
    10321 atatggatgt ttagcaatag cttttggtat actctttaaa gacttgttgc ctttttgaac
    10381 tttagtagat gcttttccgt tttcatcaac atctatccaa attgaagtac catcaatatc
    10441 ttttggttta aatagatgag caacttcatt tagtttttca gtctcaagag cccacatcat
    10501 acgatttaca tctccaaatc cagcacttct agctagattt tctagcgcta tagtacaagc
    10561 ttttgattca ctttcacgac gttgtgcacc aaattgcttg ctttctttag caaacttttg
    10621 aataaattca taacggaaag ttgcttcttt taggtctcct tttttcatag gaagtaaaga
    10681 gaaacttctc aatttatctt gatttctatt tgtttcaatt tctttcatca acatgtcttt
    10741 atcaagctta ccaagtgtag catcagcata gagttgtgca cgtctatgag agttaccacc
    10801 actagttata tatttagctg acttgtaaag tatattgaat ctttcttccc caatagtttt
    10861 atatgaatct aaaaaccaat ctacatcaaa tgcaccatca atgaaactac gtggtgaaat
    10921 aggggagaat agagcaacct ctgattcttt ttgtgcagag aagccttcat ttatatgtgc
    10981 atggaagtac caaattgtac ttttcagacc cttccagttt aaatattttt caattatgtt
    11041 tacccattga ggggcataca tagcagattc tatcaatctt aactcagtaa tgtcggtatt
    11101 tttaagtaaa ctttttaatt tttttgaatc atcttcttta gtaggatagc aatttttaag
    11161 tagagaactt aaaacatctt tttttgaata attgctacca tatgaatatc ctctctggaa
    11221 agtttcttta ccaagagcga ccaaaatatt tacaaaataa tttatacctt caaagtattg
    11281 tatattatta gctagatgag acacctctgt tggcatatca cctctacgtg attcaatttc
    11341 tataattcgg tttgtaacag tttttaaatt atctttaagc caagggtact tttctaatgt
    11401 gtcgccagcc catctaggat ttgttaatgt tcttattata tttgatgcgt tgtatccact
    11461 tatcatttct ctattaactt gctcttcagt cattaatcct aattcatgtg cacgagcaaa
    11521 cacatttatg ctagtataga aaggaaactt atattctagc aactgataat ttgaaaacgt
    11581 agtgtagaaa aacttagtaa aagaaatatc atcataaata aacgaatgtg ctttatcaag
    11641 ccaatagttt aaaatagggg catttaaagc agggcagtat tcattttgtc tgtaatagtt
    11701 tttagtaaat tcaactcttt gttttttaca ttgttctata gtcaataagt ttctaagttt
    11761 atagtatatt tctaaacaat agttaaatat ttctttatgg tcaaactcat ttagtaaaac
    11821 tcttaaaagt tttcttgtaa gtccattaaa tttaagtttt tcaagttttg tatatatttt
    11881 attttgtttt ttagagtcaa ggacatttga atatatagat gaaaaccaac ttttttctgt
    11941 ttcattatat ccacatgtac ttatactata aaataagata tcaagtatta atttgtaatc
    12001 taagtcaagt tttttactag tttctctcca aagctctgct aatggataat tatcaagagt
    12061 atcattagaa actttatatt taataggagt caagttataa gtagaataac ctaaaagtac
    12121 tttgtctaca ttacctgacc atctttcaac ttcatattca taatctgcat tttcagtaat
    12181 aagctcatca aatttttcat aaacttttat tattttattt atatccgtat cgagaatttt
    12241 ttttgcttct ttttttgttg ctacagaaac agaatcctca cgagtagata aacttatatt
    12301 tgagataatt ttattaagct ttgatgagct attagaatca tctttaaaat caaattgttc
    12361 tggaatttga actttgtttt cagggttata tattccaaaa ccattttctt tgcagtaatc
    12421 attttttgct ttacctaaca aattatcaat tagtatttga acttgagatg tattcttttt
    12481 agatttatca atatcttcta taagtaaaac aagcttatta tatagttctt gtctagcagt
    12541 attgtctttt aataagttta caatttcaag acctccaagg catttttgag aatttgaaga
    12601 ttttatcagt gaagaagcaa tattttccaa gtttgaatca tcttgttcaa gtaaaatttt
    12661 tattactgtt tgtctaatag agcttgtctt taaagacaat agattggtta tcttatctaa
    12721 ttctacatct gttagctcaa gctttctaag tagactcaat accgtttctc tattggaaac
    12781 actcttatca cttaaacatt ccaataaaaa ttcacgttgt ctatctgtct ttggttcatt
    12841 tacaaaattg actataagtg aagctcttaa atctgaactc ataagatgac aattttccat
    12901 aagcacatct ataaattgag tattcatatc gtatgctgtt aaagtcatca tacatttaag
    12961 tatttcatga gaagaaattt caatccaagt ccatggaaat acacttcctg aaaatgattt
    13021 tgtctttgaa tttaaaattt ctaaagtatg ttttaaactt tcaaattgtt cttttctagc
    13081 atcaaagtct ttgtcaatag gagtgtttga caagtcaaaa ttagtttctc tgttttgcca
    13141 actatagtag tagccaacag aaccttctac atagaaattt gtaattaccc atgctagtat
    13201 ctctaaatca tcacccttaa tgtttttaga tgctatagaa tgtttaaaat atgtactttc
    13261 tgtatgcgat aaaaagtaaa gagctacaag ttttttatat ttttcctgac aagaaagtaa
    13321 gttttcaata agagagtaag agtcatatat gttgtaagtt gcagtagccc ataaggcaaa
    13381 ataaatttca agattatcat tgctattaat tgattctata cggaactttt catcagtcaa
    13441 tgatttatat gaaagttcta aacatttacg tattattcca ggtttttggt ctgaaaaacc
    13501 aagtcctgtc catgtatcca aggctcttat aacagaacta aatcgctcta aattgttgtc
    13561 caaaatagtt ttcaacatgt atattgatgc agaaattgta ccctcatcta aactctctac
    13621 aatttgctgt ctaagtcctt cttgttgttt ggctgccaaa aggagtttag aaagcatttc
    13681 atagcattta tcactatgac tcttcatgat accaattatc atttgtcttg taagtagagc
    13741 agtttgattt tctccaaata ttacttcttc taaagcactt attacttttt gatttccttt
    13801 gtctatttct agtgctattt tatcactcat tatagagtca tagtacaaga ccttatttgg
    13861 aagagtaaga taatctataa ctgaaaaatc ataataaatt aaatcaacat agtttgaaat
    13921 aaaccttata atacctctaa aataatccac aagtttattt gagcgatacc ctttacgata
    13981 atatcctcct gaatatgtat aatccatctt tcttttaatt aattggcaaa gttcttctac
    14041 ttgttcagaa gtaaatatta attctaatgc attttttaaa ggtccagaaa ggagctcgtc
    14101 catattttta atttcgtagt agtggcaatt gtagtatttc tttatcatat ttaagaattt
    14161 gtcttcaggt tctctataat agtatgaact attttctatg cagtcccaaa gagactttgc
    14221 taagtcgtag tactgttttg aagaagattt agtaaaatta tttttaaaat tttcaattat
    14281 tttaggattt ttttctactc tagtacgttc taacatttat gtacctccaa attatttatt
    14341 ttaaaacatt cttccagcaa gcaaggtaag tcttataaaa gtaaatatat ctccactttt
    14401 cagatttata gaggaatcga gtttttcaat aacatcttca tttataagca ctttgtagat
    14461 tccatcttca aatgcctgta acgctacctc tattgccttt tctacagatt gtttattctc
    14521 attgtaaata gagccaaatc caacttttcc aatatcagct tgagattcaa tttcttcatt
    14581 agttaagaag tttattattg atttttctgg gattttctca ttatattcaa gaacattttt
    14641 agatacaatt tcagagatag cttcttttag gcaattgatg ttgtcagata catcaaaagg
    14701 ggtaagttct agcataggtt tgcgtttgcc aacagcctta actctaaaat aaatttgcat
    14761 aaaatcacct cgcaaaatat taattatgta tttagaaatt taaaatttat ctatttgtta
    14821 tattatatca ttttgtgaat tattaatgtg aattatggaa ttattttaca aaaaatagaa
    14881 aaaaagctat cttaaagtct aaaaaagcaa taaaagataa cttttaacta taatta
//
LOCUS       DAEPUT010000099        14793 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.102, whole genome shotgun sequence.
ACCESSION   DAEPUT010000099 DAEPUT010000000
VERSION     DAEPUT010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14793
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.102"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            112..624
                     /locus_tag="KRL22_003272"
     CDS             112..624
                     /locus_tag="KRL22_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBH1273716.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKEAKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            complement(779..1840)
                     /locus_tag="KRL22_003273"
     CDS             complement(779..1840)
                     /locus_tag="KRL22_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HBH1273717.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(1964..2857)
                     /locus_tag="KRL22_003274"
     CDS             complement(1964..2857)
                     /locus_tag="KRL22_003274"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBH1273718.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            complement(2867..4348)
                     /locus_tag="KRL22_003275"
     CDS             complement(2867..4348)
                     /locus_tag="KRL22_003275"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBH1273719.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISSDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSEINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELTLAIKKFLKV"
     misc_binding    complement(4456..4687)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5489..6397
                     /gene="trxB"
                     /locus_tag="KRL22_003276"
     CDS             5489..6397
                     /gene="trxB"
                     /locus_tag="KRL22_003276"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH1273720.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(6487..8310)
                     /gene="typA"
                     /locus_tag="KRL22_003277"
     CDS             complement(6487..8310)
                     /gene="typA"
                     /locus_tag="KRL22_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBH1273721.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            8522..8764
                     /locus_tag="KRL22_003278"
     CDS             8522..8764
                     /locus_tag="KRL22_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273722.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            8912..9103
                     /locus_tag="KRL22_003279"
     CDS             8912..9103
                     /locus_tag="KRL22_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HBH1273723.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            9387..11888
                     /locus_tag="KRL22_003280"
     CDS             9387..11888
                     /locus_tag="KRL22_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBH1273724.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            12048..12716
                     /locus_tag="KRL22_003281"
     CDS             12048..12716
                     /locus_tag="KRL22_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1273725.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            12700..13977
                     /locus_tag="KRL22_003282"
     CDS             12700..13977
                     /locus_tag="KRL22_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBH1273726.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            14378..14599
                     /locus_tag="KRL22_003283"
     CDS             14378..14599
                     /locus_tag="KRL22_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273727.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
BASE COUNT         5648 a         1883 c         2276 g         4986 t
ORIGIN      
        1 tgcaataata tatttaaaaa agtattttat tttcaaaact agacttcatt tataatttat
       61 cacgaaaata aaaggaatat aaatataaga gaatgagagg ttattagaga tatgagtgat
      121 tttaaagaaa ttttggcaga agagattaaa aataatccat ttggattgat aggtaaagat
      181 tggacactta taacagcaga aaatgaaggt aaagtgaata caatgactgc tagctgggga
      241 gggcttggag ttatgtgggg aaaagatgtt gcttttgtag taataagacc acagcgttat
      301 actaaggaat ttatagataa tacagataaa ttttctctta cattttttga tgaagatttt
      361 cgtaaagagc tttcatattg tggaaaagta tctggtagag aagaggataa gatatcacag
      421 attggattta atatagaaca cttaaatgat acaccttatt ttaaggaagc taaaatggct
      481 attatatgca aaaaaatgta tagtcagaaa cttgaacccc aatgttttat tgctgaaggt
      541 atagatggaa gatggtatcc acaaaaagat tatcatactt tatatatagc tgaaataacc
      601 aatgtacttg taaaagaaga ttagttataa gggttaatac tatctctaat taaattaaaa
      661 tttccataaa aggagattga cacaaaaaag ctaaggacat aaatatgttt ataaagatta
      721 ataaataacg tatttaaact ccttagcttg ataaaatctt aatttagttt tctttaaatt
      781 ataattcaga aatcaattca ttgataacat cttcaacagt acttaattta tcaattttat
      841 aggcatcatt tccacaaaat aaaagtgaat tttcaacgtc tcctttaact gcattgatta
      901 gagcttgaga aatacagtaa ggagtttctt ttggattaca aggaatcaaa caattatagc
      961 acttctttat ttctggacga tttattttaa cttcttctat aaatttgttt cttatggcgc
     1021 gtccaggaag acctacagga cttttaacta tatgaacatc ttcttcacta gcatttatgt
     1081 atgccatttt aaagttctca tgggcatcac attcgtaagt agcaacaaat cttgtaccaa
     1141 cttgtacacc acttgcaccc atatctatat attttttaac atcactacta gaagttatac
     1201 caccagcagc aactactggt atgtttctac caaatttttc tccataagta tttgcaacct
     1261 ttaaaatttc aacaaattcc ttatcatagt ctatagaatc tatgttatca agttcctcgt
     1321 tagagtatcc aaggtgacca ccagcttttg gaccttcaac aactattaag tcagcagtag
     1381 ttttctcttt tctatcccac atttttaaaa ttacattagc agcttttgca gttgaaacta
     1441 tgggtgctat ttttacatta cttcccttta ctaatgatgg tagcttatta ggtaatccag
     1501 ctccagatat tataaggtct acaccagctt taacagcttc ctttacgtat gtttcatatt
     1561 ctttcatagc taccataaaa ttaataccaa taataccacc atttgagatt tctttggcct
     1621 tagaaatatg tttttttata gctcttaaat ttgcatttat agtattagtt tcaaaatctt
     1681 cctcatcata tccaatttga actccagaaa ttacaccaac accaccaagc ttagcaactg
     1741 caccagctag tgatgaccta gatataccaa cgcccattcc accttgaatt ataggaactt
     1801 ttgcaactaa atctctaatt attaactctt ttatgataat ccctcctcaa tgtaaacatg
     1861 tttaaagaac tagattataa tacttaatat tattacctag tcctaattat tatactacaa
     1921 attataataa aagagtagtt atattttgta tagaagacga taattatatt atatttaaaa
     1981 cagctccatt agaatcgcaa cataactctt ttatttccca atcagatttt agtttttgta
     2041 ggtaattttt catattatcc acaaaactat catcattttc ttttattaaa gacattatag
     2101 taggtccagc tccacttaaa aatactccaa tactatttaa ttgttcagat ttttcaacaa
     2161 tatcattgta gttctcaatt agagttcctc tataatcttg atgcaatttg tcttgacaag
     2221 ctactttaag taggtcaaag tttttgttta gtaaggcaga tattagtaaa gcaactctac
     2281 taacattgaa taccccatca gaatatggta tttcctttgg taaaacacct ctagcttttt
     2341 ctgttgataa cttaaaatta ggtatcattg cacaaaattt aagttcttca ggaattttta
     2401 taatatcata atgtatgttc tcattatcag taacagatac aatcatattt cctaaaatag
     2461 caggagcaac attatctggg tgaccttcta tttctgaagc tatatttagt aattgatttt
     2521 tatctaaatt agcacctgat agagcatttg cagctataac tccagctact atacaagagg
     2581 cactactgcc aagacctcta catataggta cttcactttg gatttttatt ttgataccag
     2641 caggtatttt ttctggttta actctatcaa aaaagtactt catagatgta taaactaagt
     2701 tattttcgtt tttgtaagca tcttcacaac cttctatttc aagaccactt tcaatttctt
     2761 caacataaaa tttattgtat atatttaacg caattccaag acaatcaaat cctggaccta
     2821 tattagcact tgttgcagga actataatct ctaacataat aatcacctat acctttaaga
     2881 atttttttat agctagtgtt aattcatctt tttcataaat atctttatgt agtatttctg
     2941 catttttaag atttttaata ggttttggaa tatctatttt agaaatactt gataatctat
     3001 caattatagc aaagtcatca aggtctttaa aatcacaatc tatagacttt agaacatctt
     3061 cagaaaactt gaatggactt gcagtactta caataacagt ttttgtgtta tcagaagttt
     3121 cttttttata tttttcataa caattgtatg caacagcagt atgagtatct atcaaataat
     3181 tataattttt aaacacattg tttatcgtgc ttttaacttc ttcttcattt gaatattctc
     3241 catagaatga ggctaaattt ttttccatat catcacttat tttgtagact cctttatcac
     3301 taaggtctga taacagctta tttacaatat cagtatttct atttgatatt tcaaacagta
     3361 atcgttctaa attacttgaa attaatatat ccatagaagg agaagtagtt aatttcaatg
     3421 ttctattttt atcatataca ccagttttaa agaaatcata aagaacatta ttatcatttg
     3481 atgcacatat caatttgttt attggaagac ccatttgttt ggcataatat ccagctagaa
     3541 tattaccaaa attaccagtt gggacaacaa aatttatttt atcatttaaa tttatctcac
     3601 tattgctaac taatttcata tatgaataaa aatagtatgc aacttgtgga agaagtcttc
     3661 ctatattaat tgaatttgca gaagataata tataattatt atccaatagt ttttgattaa
     3721 attctttatc agaaaaaatc ttttttacac ctgattgtgc atcatcaaaa tttcctttta
     3781 taccaactac atatgtattt tttccagttt gagttttcat ttgaagtttt tgtactgggc
     3841 ttacaccatc ttctgggaag aatacaatta tctttatttt atctatatct ttaaatccct
     3901 caagtgcagc tttgcctgta tctccagatg tagcagtaag aatcacaaca tctttctcta
     3961 aattatcttt ctttatagat gttttaagaa gatgaggcat tatagtaagt gccatatctt
     4021 taaatgctaa agttggaccg tgatatagtt ctaagaaata agtatcattt actttattta
     4081 atggagctat actactacaa tcaaactttt catcatatgc attttctata caatttttaa
     4141 tttcatcttc agtaaaatca cataaaaatt tactaagtac aaaaaatgct atctgagaat
     4201 acgttaaatt tactaaattt ataagttcat tttttacatt gggaaattca cttggaacat
     4261 aaagaccacc atcacttgat attcctttta ttattgcttg tgatgcagtt actttttctt
     4321 cggtgcctct cgtacttgaa taatacattt tttataatcc tccatatatt ttaaattttt
     4381 aattagctaa ttaaattaga tacagaatat tttaaaaact gaatttaggt aataaaaaaa
     4441 gaccctcatc cctaaaaaag ggacgagaat ctgtttcccg cggttccacc caaattgatt
     4501 ttaaaaaatc cacttgatac tttaacgcaa gtaataaaaa cgtctattcc tactaaaatc
     4561 attaagataa cttcggatag aagctcctag gtagttttca atccttctaa ttagggaaac
     4621 atttcagcta gtagtttcct tctctggtaa tcgattcaga tttactcttc ctaatcaatg
     4681 cctttcaata ttcttaatat tattaattat tctagtttat aaaacagaca aagtcaagta
     4741 ttaatataaa aatttggaaa aaatattttt taaattgtaa aaaaattgta atcaaattga
     4801 gtattagaaa aatatttttt taactttttt aaaagtttaa aaacctagat tttcatagtg
     4861 atgaagctgt ttttaatgaa agtaatcaaa agataactat taaatatctg taatattaca
     4921 attttatact acactatatt acaaaaaaag tttacaaaac tttaatttga aaaatgtaat
     4981 tatatggtat atcatataaa tataagtaaa tagtgctaat atttaaacta ttaatcataa
     5041 ttggttcaac aaaagtatat agttaataat gtttaatttg aagaaattgt tagtgtgaaa
     5101 ttacatatat attcaaatta aattcataaa tatttcacat aataatagta tactataaac
     5161 aaaaggaggt attaaatatg ggaatagtac ttataacagc agcattagtt ttggttatgt
     5221 atggactttc aattctatca tatatatcag aaagcaatat attagaagac actgtaaatg
     5281 ataaccaata aggttttgaa ttatataaat aagtgagaac tgtaaataaa agttaatttt
     5341 tatttgcagt ttttttatat atatgtaaaa taaagttaat taataaaaaa taatgttttg
     5401 tttatagtat atatggataa taatagtaaa gtataagaat gatgagaata atatataaga
     5461 aataataata taaagagagg taaacgttat ggtagatatc attgtaattg gtgctggacc
     5521 agcaggttta acttcagcaa tttatgctat gagagcaggg ttaagcgtta cagtatttga
     5581 aaaaaatatt tatggaggtc aagttgcaag tacctctgag gtagaaaatt atccagcagt
     5641 tcaaaagatt tctggggtag aattttctaa taatatatac aatcaagcag ttgctcaagg
     5701 tgttgatatt cagtttgatg aggttgaaga gataaattta gagggaaaag taaaggttgt
     5761 aaaaacttct tcaggtgaac ataaagcaaa ggctgttatt cttgcaaatg gagttgaaag
     5821 acgtaaatta ggttgtgcag gggaacaaga atttacaggt agaggagtat cttactgtgc
     5881 aacatgtgat ggagcctttt ttaaagataa agaagttgct atagtaggtg gaggaaatac
     5941 tgcactagaa gatgctttat ttttagctaa taattgtaca aaagtgtatt taattcacag
     6001 aagagatagt tttagaggtg aagaagtgtt ggagaaatct gtgaaagcaa gagagaatat
     6061 tgagatactt tacagtcatg gtgtagaaaa aatagaagga gaaaagactg tatcgaaaat
     6121 agaagtaaaa aacttaaaga ctgaagaaaa aagaactata gatgttagtg gtatttttat
     6181 tgctataggt cttaaaccta ataataaaat gtttgaaaat gttcttgatt tggatgaagg
     6241 tggatatata atttcagatg agtcttgtac aacatcagta gaaggtgtat atgtagcagg
     6301 agatagtaga actaagtttt tacgtcaaat aataacagca gcatcagatg gagctattgc
     6361 agccgttcaa gcagctaatt atataaatgt tgaataatat aaatttcaaa taaaaatagc
     6421 catataaact gaaataattt ttcagtacta tatggctatt ttgttaatta gaggtaaatg
     6481 tacgttttat ttaccttgtc tagatttgtt atatcttaat ctatcatgtt catttaagaa
     6541 tctttttcta agtcttatag aatcaggtgt aatttcaact aattcatcat cttctataaa
     6601 ctctagtgct tcttcaagag taaatattct aggaggagat aattttatag catcatctga
     6661 accagaagca cgtacgttac tcattttctt gtttttacaa ggattgacta ccatatcatc
     6721 ttttctggaa ttcataccaa ttatcatacc ttcgtaaact tctacaccag ggtctacaaa
     6781 cattacagct ctatcactta aggcattaag agaatacccc atagtaacac caggtccttg
     6841 tgctattaaa acaccatttc ctcttgaagg tatttctcct ttaaattctt caaatttttc
     6901 aaatgaacga actaaagtac cttctccacg agtagcgttt ataaattcac ttcgatatcc
     6961 taaaagacca cgagtaggtg ctaagaactc tatttttaca tagtctcctt ctattgacat
     7021 agactccatc ataccttttc tcatgtttaa ttcatttata atagtaccag agtaaacttc
     7081 aggacagttt acaacaactc tttctattgg ttccattagt tttccatctt ctttatgcat
     7141 taaaacttca ggtttagaaa caccaacttc ataaccttca cgtctcatat tttcaagtag
     7201 tatagataag tgaagctctc cacgtccaga aactttgtat ccatcagtag tatcaagagg
     7261 ttcaacttta agaccaacat ttacttcaag ttccttttca agtctatctt tcaaatgtct
     7321 agttgtaacg aattttccac tttttccaac gaatggagag tcgtttacta agaagttcat
     7381 agaaagagta ggctcttcta tttttatcat ttccataggt agtggactat ctaaatcgca
     7441 tatagtttca cctatagata tatcaggaat accagctata acaactattt ctccactagt
     7501 agcttcatca acttcaactt gttttaaacc ttcatataca gaaagttttg atacttttcc
     7561 tttagataca acagaatctt ctctacatat agcaacttgt gtattgtttt taagagtacc
     7621 tttgtaaatt ctacctatac caagtctacc tacataatca tcatatgcaa gagctgatat
     7681 ttggaattgt agaggttcat tatcgtaatt aggataagct tcaacgtgat ttacaatagt
     7741 tttaaataga ggagaaaggt cttcactatc atcatccatt tcaagtttag caataccttg
     7801 tttagcaata ccatatatta taggaaattc gcattgctca tctgttgcat ttaagtctac
     7861 aaataaatcg aaaacttcat taactacttc ttccgctctc tggtcttttt tatcaatctt
     7921 gtttataaat aatattggtt ttaaaccgaa ctctaaagat ttttgtaaaa cgaatctagt
     7981 ttgaggcatt gggccttcac tagcatcaac taatagaata actgtgtcaa cagttttcat
     8041 aacacgttca acttcagaag aaaagtcact gtgtcctgga gtatcaacta tgtttatttt
     8101 gtaatcttca tagtttattg cacagttttt tgaatatata gttatgcctc tttctttttc
     8161 aaggtcgtta ctgtccataa cgcagtcttt aactacttcg ttctttctaa aaacaccgct
     8221 ttgagaaagg aaagcatcaa ccaatgttga ttttccagcg tcaacgtggg ctataactgc
     8281 gatatttata attttatgtt tttgtgacat ttttgttgct cccttcgatt aaaataactt
     8341 attaattata gcacaatata ttattaggta caaggaggaa tatattaaat tgtattaata
     8401 tagtttaaat tggataaaac tgttagtttt gcatctgaaa attattctgt ttaaaaaaat
     8461 tttttagaca aataataacc ttaatagata aaaagattaa taaaagagta aaggatgata
     8521 tatgttggaa gtaaccaaaa taataattaa atattttgca agtgaaagtg atacttttgt
     8581 aaaagaagaa gtttgtaatt ttgaagaact tcttaagtgg tctcataaat ttattgaagg
     8641 taaaaagata gaagatgttt tgtatataaa gtctaaagaa aactataaag taaatgtgat
     8701 taagtcttta gaaattaagg aattggaaat agtgagaaaa caacagatac caccgtacat
     8761 gtagtattaa taatatgtaa aattaatatg taatactcac aataggatat aaatggtata
     8821 tatggtaata atttatatta aaaaaacttt tataaagttt atatttgggt ataaaagtat
     8881 taattagaca ttaattagga ggaacttaaa tatgataaga gtatgtccaa actgttcaaa
     8941 tgtggatgta aataagctaa aaactttggt tggagaagaa aatgtaaaga ctggttgtat
     9001 aggtcagtgt agagcattta aaaaagaagc tgttggaata atagacaatg agcttgaaat
     9061 aaaggaaaca gaagcagagt tttttgaagc atgtaaagaa taaattttaa ataaattata
     9121 ataaatagag catctaaatt gtataagcat taaacaattt agatgctcta tttttatata
     9181 tacatttaat tatgagtata cttttctatt aaatacaaat aaatataact aatacattta
     9241 tttattaaaa aaatattgat ttaatatacc tatagggggt ataataaaaa tatagatttc
     9301 taaataagta atttatcaat attacatatc aaaataaaac gttacaaatt agctgaaaat
     9361 atattgaaag aaaggaagat tttattatga gttcaaataa agtggtagaa agttataaaa
     9421 ttacaggtat gacatgtgca gcttgtgcaa aggcagtaga gagagtaact aagaagatgg
     9481 atggagtata tgaccaaagt gtaaatatag ctactgaaaa acttaaaata gaatatgata
     9541 attctaaggt taattttgat gatataaagc aggttgtaga aaaagcagga tatggaatta
     9601 taaaggaaga aagtaataaa aaaattgata tgaaaattga tggaatgaca tgtgcagctt
     9661 gtgcaaaagc tgtagagaga gtggtaaaaa aattggatgg agtagaaagt attagtgtga
     9721 atattgcaac agataaagct aatatagact atgacccatc aaaagtaaaa ttatctcaaa
     9781 taaaagcagc tattgaaaaa gctggatata aaccaataga agaggtaaga aataaggttg
     9841 atgtggatga agataaattg agaaaagaaa gagaaatgaa gtctttattt gttaaattta
     9901 tagttgcaat agtatttgca gtacctctgt tttatatagc aatgggacct atgataataa
     9961 agcctatagg gccatggcct ttgccagaaa ttataaatcc tatgacaaat acttttaatt
    10021 atgcattaat tcagttaatt ttagtaatac cagtaatgat agctggttat aaattttata
    10081 taaatgggtt taaatcactt ttttctttaa gccctaatat ggattcttta gttgcaatag
    10141 gaacattagc cgcattttta tatagtctat atacgacact acaaatagcc aatggacaaa
    10201 ttcaaggtat gcaccatcat cagttgtatt atgaaagtgc aggaataata atagcactta
    10261 tcttacttgg taaatattta gaatcaaaat caaaaggaaa aacatcagaa gcaattaaaa
    10321 agcttatggg gctacaacct aaaactgcaa tagtgttagt tgatggtaaa gaagttgaaa
    10381 ctcctataga agaagtagag ataggagata tactattagt aaaaccagga actaaaatac
    10441 ccgtggatgg agttgtaata gaaggatata catcagttga tgaatcaatg cttacaggtg
    10501 aaagtatacc agtagaaaag aatgttggaa gtaaggtgac aggagctagt attaataaaa
    10561 atggtgttat taagtttaag gctgaaaaaa ttggtggaga tactgctctt gcccaaataa
    10621 taaagttagt tgaagatgca caaggtacaa aagcacctat tgctaaactt gccgatactg
    10681 tatctggata ttttgtacca atagtaattg caatagctgt agttgcatca ttattgtggt
    10741 ttttaatagg aggaaaagat atagtatttg tacttactat atttatatca gtacttgtaa
    10801 ttgcttgtcc ttgtgcatta ggattagcaa caccaactgc tataatggtt gggactggaa
    10861 agggcgcaga aaatggaatc ttgataaaag gtggagaggc actagaatct gcacataaag
    10921 taaatacagt gatatttgat aaaacaggta ctataacaga aggaaagcca aaagtaacag
    10981 atatagtatt aaataataat gtaaaagaag aatatcttat caagattgct tcaagtgcag
    11041 aaaaaggttc agagcatccc cttggagaag caatagttaa gtatggagaa gagaagaata
    11101 taaaatttga aaaagttgat aattttaaag ctataccagg tgctggtata caagttacta
    11161 ttaatgatga aagtatatta cttggaaata gaaagcttat gaatgacaat aatataaagc
    11221 ttggggattt agaagaaaaa tcaaatatat tggcaagcca aggtaaaaca cctatgtata
    11281 tagctgtaga tggaaattta tcaggtataa tagcagttgc agatgtagtc aaagaaagta
    11341 gtaaaaaagc aatagaaata cttcatgata tgggaataaa agttgcaatg gtaactggag
    11401 ataatgcgaa aactgcaaat gctatagcaa atcaagtagg tatagatatg gttttggcag
    11461 aggttttacc agaagataag tcaaaagaag ttgaaaaact acaaaatcaa ggaaagtttg
    11521 ttgcaatggt aggggatgga ataaatgatg ccccagctct tgcaaaagca gatataggga
    11581 tagcaatagg aagtggaacg gatgtagcca ttgaatctgc ggatatagta cttatgaaga
    11641 gtgatttaat tgatgttcca acagcaatta aacttagtca tgaaactata aaaaatataa
    11701 aacaaaacct attttgggca tttggatata atacaattgg tatacctgta gcagcaggaa
    11761 tattatatgt atttggagga cctttattaa acccaatgat tgcagcagca gcaatgagct
    11821 taagttcagt ttcagtcgta tcaaatgcac ttagacttaa aaacttcaag gcatataaga
    11881 gagattagat taataaatta aataaaatgt atccaaaaga gctatcttta aattaaaagg
    11941 attaatttac aaattaagat agctcttttt tcatgtaaaa ttcacaacaa taagataaaa
    12001 tataagtaat atacgaaatt ttaaataaaa tagaaaggat tgatagaatg aattcgtcaa
    12061 tacttgtaat tgaagatgat tcaaatatac aagagttaat atcagaattt ttaagtgcag
    12121 aaggttatca agttgataca gcaaatgatg ggttggaagg tatacaaaag tttaagcaag
    12181 gaagttatga tttagtaata ttagatataa tgatgccaaa cttagatggt tatggagttt
    12241 gtaaaatgat aagaaagtca tcaagcgttc caattatatt tttaactgct ttaaatgatg
    12301 aaggagacca acttaaaggg tttgacttag aatgtgatga ttatataaca aaaccatttt
    12361 catttaatct tcttataaaa agagtagaag caattttaag gcgaagtaac aagactataa
    12421 atgacaaatt tatagttttt gaaaaattaa aattagattt aaacacatat attgcagaga
    12481 tagatggaga acctatagaa cttacactaa aagagtttaa tatattaaaa gctttgatag
    12541 aaaagtatcc acaagttata actagggaag gtcttttgga tagtatatgg ggttatgact
    12601 attatggaga tactaggatt gttgatgcac atataaaaaa tataagaaaa aaaatatcat
    12661 taccatatat taaaactgta aaaggaatag gatatacact tgagaaggat atttgataag
    12721 tgggaaaagt taagtataaa gtataagtta ttttcaataa cgacatcatt attaatagca
    12781 ttagctttaa taatatatct aattttatat tttttattgc catcatatta tcatgagtat
    12841 aaaattgagt ctcttcaaga aagtttgaaa tctttagtag atagttcaat tcatttcgat
    12901 acatatactt tagaagaaag actttattat atggctaaag accaaaattt ggctatttta
    12961 ttaaaagata accaaggtaa aattgtatat ggtaagaatg aagtagttat tttaagatat
    13021 agtaagtaca tgattaatag tcttgaggat gagtatagaa cttctatacc tatatatact
    13081 aaagatgcaa aagatggtcc atatacttta gaactcgtta tgccattaca accaattgac
    13141 gaagcaaacg aagttataag aaaactaatg ccatacatca tatcaatagc aatattgata
    13201 gcgattattg gagcatatat atattcaatt gtaataacaa agcctcttat aaacataata
    13261 gagagtgaga gagaacagga atatagaagg aaggattttg ttgctacaat atcacatgaa
    13321 ctaaaaactc caataaccat aataagtggt caaattgaag gtatgattta tagtgtaggt
    13381 aagtataagg atagggatac ttatctgaaa aaatcgtatg agtgtacaca agaattaaaa
    13441 gatttagtaa atgaaatgat agaggtttca aaatcagaaa tacttgaaaa agatttgaaa
    13501 ttggtatcaa taaatataag tgaattatta aatagacttg taaagagaca agtattttta
    13561 atagaagaaa aacatatgaa aactatttta aaaatagaag aaaatttgga aattaaagca
    13621 gaccaagaga gaataactaa ggcaatcaat aatataataa ataatgccat aaaatattct
    13681 cctgaagaat cagagcttat aattagactc tatgataaaa ataaacgaat aagtaaaaag
    13741 acttctaatc aaagagtggt tttagaaatt gaaaatactg gtgtaactat cgagaaacgt
    13801 tatttagaag aaatatttaa tccattttat agaatagaaa aatctcgttc gagaaaaact
    13861 ggaggaagtg gacttggact ttatatagtc agccaaattt ttaaaagtca tgggtttgat
    13921 tatagcataa aaaacaaaga aaactctgta gtattcacag tagaatttaa aaattaatta
    13981 cttattataa agaatatata actttcaata atagttcatt ttaaaatcac aaaaaattca
    14041 taatgaaact gtattatata aatataaaga agcttaaaac cataaaatac accaactata
    14101 atgatgagat ttccttacat cctccatata agtcatcatt atagtaaccc aacaattaag
    14161 ttactatgaa tttaaaaaat aacaccgagc atataatcta tgcttagtgt tatttttatt
    14221 ttgaaacaaa aaatatttaa tttattgaaa tgtatagatt tagatagttt aaactatatt
    14281 taagacttaa aaattataat tgatattaca aataaatata tgtactttgg gaaaaataaa
    14341 tataggaagt attatattta cagaggaggt agttttgatg gatagattaa aaagagatat
    14401 gaaaaatatg aaagaagatt taaaagaagg tgttaaaaag acagcttatg ttatgaaaaa
    14461 tacagctgaa gatttgaaag atgatgcaca aggtgctatg gtaaacttag aaatgaaaaa
    14521 agatgagatg atggaaagat atgaacaaaa gaaattttct aaagaattag agaagcaaat
    14581 gaagaatgaa atgaaataag cttttattta tgaataacaa attattgtat tcatataaaa
    14641 agtagccagt aatattaaat agtttattta aggaaataga ctttctaaaa ataactgtat
    14701 tagatttaga aagtctattt caaattagtt ttataaatag acataaggat aaagtagatg
    14761 ttatagaact agattttaaa aaatagatac taa
//
LOCUS       DAEPUT010000100        14753 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.103, whole genome shotgun sequence.
ACCESSION   DAEPUT010000100 DAEPUT010000000
VERSION     DAEPUT010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.103"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..420)
                     /locus_tag="KRL22_003284"
     CDS             complement(<1..420)
                     /locus_tag="KRL22_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273728.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLGHIDIDSKLIVDMDFINKKNKII"
     gene            complement(413..802)
                     /locus_tag="KRL22_003285"
     CDS             complement(413..802)
                     /locus_tag="KRL22_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1273729.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            994..1440
                     /locus_tag="KRL22_003286"
     CDS             994..1440
                     /locus_tag="KRL22_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273730.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            1704..2429
                     /locus_tag="KRL22_003287"
     CDS             1704..2429
                     /locus_tag="KRL22_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1273731.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            2416..3660
                     /locus_tag="KRL22_003288"
     CDS             2416..3660
                     /locus_tag="KRL22_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1273732.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFKSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGQGTEFHIIFHKMYDSD"
     gene            3740..4417
                     /locus_tag="KRL22_003289"
     CDS             3740..4417
                     /locus_tag="KRL22_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273733.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLDLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPIGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            4418..6979
                     /locus_tag="KRL22_003290"
     CDS             4418..6979
                     /locus_tag="KRL22_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273734.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNAEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDILFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            7200..8474
                     /locus_tag="KRL22_003291"
     CDS             7200..8474
                     /locus_tag="KRL22_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1273735.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(8635..11676)
                     /locus_tag="KRL22_003292"
     CDS             complement(8635..11676)
                     /locus_tag="KRL22_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HBH1273736.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKGNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTPENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKIDDNNISNSVKEAWKKRNGKDYYLVDEKYTSQSYMFGSVKATLALSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSSFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            11882..12181
                     /locus_tag="KRL22_003293"
     CDS             11882..12181
                     /locus_tag="KRL22_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBH1273737.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(12419..14647)
                     /locus_tag="KRL22_003294"
     CDS             complement(12419..14647)
                     /locus_tag="KRL22_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBH1273738.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT         5610 a         1784 c         2192 g         5167 t
ORIGIN      
        1 tattatttta tttttcttat ttataaaatc catatctact attaattttg aatctatatc
       61 tatatgacct aatttagaat aaatttctga tttaagcttc ttagcttttt tatgtgtatg
      121 aatatatagt atactttcat ataataaaaa acctataata ccaataaaat aggaaagttc
      181 caatttatta aatgtaaaga ccagaataaa aactaatata aagtctataa taaaacctaa
      241 agataatagt tttttaaatt ctttatctaa ctttataaag taattataat ttttatgctc
      301 ttggtctata gaaactccat agatgtgttt tttacctaca aaatagggca taaaataaaa
      361 tgtagcatac atcaaaatta gaactggaaa tattgtaaat agacattcaa tcttactcat
      421 aatatttcac ctcatacttg tcaaataaac ttgaacttag tgacaaaaat tcttctttac
      481 taatacctga taaataagat tttgccacca ataattccaa gtcaagttta tttttttgac
      541 gagttgtatt atctattttc attggtagtt gagctacaat agcacctttt cttctatcaa
      601 tatttaagaa tccctcttct tttaattcat tgtaggattt gttcactgta tgtaaattta
      661 caccaatatt ttcagccata cttcttacag atggaagtga ttcatttatt ttcaattctc
      721 ctgaagctat agccttagtt atttcttctt taatttgtac ataaatagat ttatcactat
      781 taaaatctaa atttaaaacc ataaaaaacc tccattatgc tttataaatg aaaacgattg
      841 ttatatacat agtataacat aaaaaataat aacaaacaca aaatataagt ttatattttg
      901 taaaaattgt aatttaaaaa ataacataat ttttattaaa ataatacaga tactatttat
      961 agatagaaat aaaaattaga aaggagaaaa aatatgttaa catatttaat gaaaagacaa
     1021 atgcataaaa aagatgatgg aatgagtaaa ccaatgatga ttacaggagc tgtaattaca
     1081 ggtgtaggag catatgctgt atataaaatg gtaaaaagcc ataaatctaa ttctcaaatg
     1141 gtcaatacaa attattatgg aaatagcgat tatgatgatt ataaatatga cgaatttgat
     1201 tatgactgtg attgtagaga cacaaaacaa gattatgaat atgaagaatt aaaaaaaaaa
     1261 gtaaaagaat ttaattcaag aagaataaat tgtgaaaatt gtccacatgt ttctcaagaa
     1321 gaaatgatgc aatatgtaaa tagtgttaaa gatgtaaagg aagagattga tttacatgaa
     1381 gatgctaaaa aagataatat ttacaaagaa gatgaataca aaaaatatga agaagaataa
     1441 gtaatatttt gtataactga acaaatagta atgtcaaatt atttaatatc tagttttaat
     1501 atgtaagttg taacttaact tgaaagaatc agtatcattc tttagatagt taagtaacaa
     1561 cttacatttt atttttataa attttaatag ttctttgtga ctattttgta attttagaaa
     1621 tattttagta tccagggtaa ttgtgtataa taaaacttgt atagatagat agtatgaaat
     1681 taagcagata gtttaaaatt aaaatgaaaa gaaaggaaat agttatgtta aagttgttga
     1741 tagttgaaga tgatagtact atatcttttg gaataaagta tgctttagaa caagaaggat
     1801 ttagtataga tatatcaaag gatttatcta gtggaaaaga aatgatttct tctaatgaat
     1861 atagcatgat actgttggat gttacattgc cagatggaac tggttatgag ctttgtcaat
     1921 atataagagg attctctcag gttcctataa tattcttgac tgcttgtgat gaagaagtaa
     1981 atattgtaat gggtctcgat ataggtggag atgattatat aacaaaacct tttagaatta
     2041 gagaattaat atccagaata aaagctgttt taagaagaaa aggtaatact tcagaagaaa
     2101 ataagaaaat acttaaattt ggagatttaa gtatatatac attagaagct agagtatata
     2161 aaaatgataa agaaatattt ctgacatcag ttgaatataa acttctttta attcttatac
     2221 agaataaaaa tactgtttta agtagaactc aaatattgga aaaactttgg gatgtaactt
     2281 atgattttgt aaacgacaat actctaactg tttatataaa aaggcttaga gaaaaaatag
     2341 gtgatgattt atgtgaacca atctacatag aaactgtaag ggggattggt tataaatgga
     2401 taggaagtga aaatagtgtt tctatataat ccagaagtga agaagttttt aagtaagtat
     2461 gttactttga tgtttattgt tatcataata tctattggat ttagcataat caacgtgtcc
     2521 ttaactaaag agatggttgt aagaaataat caggctataa taggaacttt atcaagcaag
     2581 tatccaaact tagaaagtca gatagtagac ataataactc aagggaagtc tatggagaac
     2641 atagattatg gtcagaaaat attaattaag tataattatg ataaatctat taggataaac
     2701 tctgagccta ttatttctaa attagtttta gagactatca aaataaatat aatattagta
     2761 tgtataatat ttattttgat atttgtgttg gttgttagat attttaagtc aatttacaat
     2821 gatttatcag atatgactaa gtatgtttac tatagttcag agggtaagcc atttgatatg
     2881 aaaaacaaga atcaagaagg gcagataggt cttctaaaaa ctgaactctt aaagatgacg
     2941 acaattctta atgaaaaggt tgaactttta aaaagagaaa agatattttt aaacaataca
     3001 atttccgata tatcacatca attaaaaact cctatgactt ctttaataat gttgaatgat
     3061 ttattatata atgatgtacc atacgaagta aaaatcgatt ttttaaataa gataaaaaat
     3121 caattaaata gaatggattg gttgattaaa agcatgctta aattatcaaa ggtagaagca
     3181 aaagtgataa attttaaaaa agataaggta aaatttagtg aactcataca tagagcaatg
     3241 ctatctatga aaatacctat ggagattaaa aatcaaaaac tgactataga gggaaatgat
     3301 aatgtatctt atattggtga tattgattgg tccgtggaag cattagtgaa tataatcaaa
     3361 aattgtgtag aacatactcc tgaatttgga aatataatta taacctataa agaaaatcca
     3421 ttattttctg aactaataat aaaagatgag ggtgaaggta tagataaaaa agatatacca
     3481 catgtattta aacgattcta tagaggaaga agtagttcaa aagaagatag tgtaggaata
     3541 ggtcttgcaa tgtcaaaatc tataatagaa agccaaaatg gcgatatata tgtaaacagc
     3601 gaaaaaggtc agggtacaga atttcatata atatttcata aaatgtatga tagtgactaa
     3661 tctgtaatat ttaattcact ttatagtaat agccaaaacc taatatatga agtatagaat
     3721 ataaatattg gaggtagtta tggaaatttt aagagtagaa aatctaacta aaagttatgg
     3781 taaaaatgaa acaaaagttg atgctataaa aaatgtaagt ttatcagttg aaaaaggaac
     3841 gtttatagca ataacaggtc caagtggaag tggtaaaagt accttattac atttattagg
     3901 aggagttgac agaccaacta gtggtaaggt ttatataaat gatgttgata tctataattt
     3961 aaaaactaag gatttggcga tatttagaag aagaaatata ggtcttatat atcaatttta
     4021 caacttaatt ccagtcttaa atgtgaagga aaacatattg cttccagcag agcttgacaa
     4081 tagagatatt gatagagaat attttgatga tttaatgaaa acattagatc taattgatag
     4141 agaaaagcac cttccaaacc aattatcagg aggtcaacaa cagagaacct ctataggacg
     4201 tgcattaatt aatagacctt ctataatatt agcagatgag ccaataggta atttagatag
     4261 taaaaattca aaggaaatat tagaattgtt aaaattgtca gtaaaaaaat acaatcagac
     4321 actaataatg ataactcatg acaaaaatat ggcacttcaa gctgatagaa ttataagcat
     4381 agaagatgga atcataaaaa gtgatgaggt gatgtagatg aatttatata catcactaac
     4441 cattagatac ttaaaacaaa ataaaagaag aaccattgta accataatcg gtataatact
     4501 ttcaacagct ttaatttgtg gtataggaaa tatatttgaa agttttatgg attatcaaat
     4561 gagagaaact ataaagaatg atggaagttt ccatgttaca ttttatgatg taaatagaaa
     4621 aaatgcggaa tatgtaacga aatcagctga aatagaaaaa catgcattta ccaaacaact
     4681 tggatattct aaattagaaa atagtgaaaa tgctatatta agtataaagc aatatgataa
     4741 aaatgcaata aacggatata aagtttctat aaaagaaggt agatttccag ctaaggaagg
     4801 agaaattgtt ttaagtgaaa gtattattaa tcttatagat gataagttaa aaataggaga
     4861 taagataact ttaaaagtag gggatatgtt tgactcaagc aagaaaaaga ttgatagtat
     4921 gacatttcat gaaggtgatt atatagcaaa tgaaaaagat agaactttta aagttgttgg
     4981 tataattgaa aaacctgggt ttgaacgtta taatggaatt gcaacagcta tagcctactt
     5041 taatcctatg aataattaca atgatacaat taatgtatca gtagcagtaa gaaatcctaa
     5101 agatgtgtat aagataagta ataaaataag taaaaatata tattcaaata aagataaaga
     5161 agcagtttcc gatatgataa aatacaatga acatttattg aggttacaag gtgctagtaa
     5221 gtattcaaat ataaatagct ctataaagtc tataattata gcagtaacta ttttagtaat
     5281 catatgtaca attgctacag tgtacaattc ctttagtatt tctataaatg aacgaaaaaa
     5341 acagtttggg atattaaatt ctataggtgc tacatctagt caaattaaaa gattagtttt
     5401 tatagaaggt attataatta gtttaattgg tataccaata ggactaatat ctggaacagt
     5461 agctatagac atattgttta aaattataaa taagtatttt actgaatcgg ttgttactaa
     5521 gatgagtttg cagatagtgt ataatccaat aataattatt gttagtataa taatagtttt
     5581 gcttacaatc tttatatcaa ttctactacc tgcaatatcg gcttctaata tttctcccct
     5641 caatgtgatt aaaaatactg gagagtataa agtgggcaaa atcaaaagct caagacttat
     5701 taaaatgatt tttaaaactg aaggagtact tgcatataaa aatattagga gaaatagaaa
     5761 aaaatttata ataactcttt tttctttaat ggtaagtata ataatattta tatcttttag
     5821 tggctttaca ttacttttac taagaggtga agaaattaga aattctcaaa gaaaatatga
     5881 tttgtattta actgcaaaga acacagctag gtctgtagag gatactataa gtgaactaga
     5941 agatattgat gggataaaaa actttgaatt ggcaacagga caatatgtgt ctataagagt
     6001 aagtgaaaat aaaataaata aatccaagga agatttaatc aggaaatatt atcaaaaata
     6061 taagattgga gatagttatg aatatgattt cagtaataat gaattaattt ttccaggaga
     6121 ttttgcagta aaaaacaaaa taaataactt agtacagggc tcttttaata aagagagagc
     6181 aattgaagaa aatggtgtta tattagttag aaaaagtgca tttgaagaaa atgggaagaa
     6241 aggtgtagta gaacttacca actataaagt aggagataca gtaaattgtg aatatcttga
     6301 tgaaaatgcc ttaagtaaaa aagtaaaggt caagattctt gctataactg acgaagaacg
     6361 tctaggtctt ggttatcaaa atatggggtt acaatttata acttatgatg aagttgctaa
     6421 aaatttaaat ttaaaattaa gtaaaagcct tatatttatt gattcaggag gaagcattaa
     6481 gactaagaag gaaatagaag ctttggcaaa taaaaataat tttaactttt atgatgaaag
     6541 tgcaagcaat gaaagtgaaa aacaagattt aaaggttatt aaaatatttg tatatggttt
     6601 tatagtagtg atatctttag tgagtgttac aaatattcta aatacagtaa gtacaagtat
     6661 aaatctaaga aaaagagaac ttgcagtaat acaatctata ggggttactc ctaaaggatt
     6721 taggaaaatg atatatttag aaagttttat atatggtata ctgtcattgt tgtttggaat
     6781 accaattagt attggtataa ttctaattat gaataaactt atttcaggtg taattgaatt
     6841 ttctccgatt ataccgtgga cagccatagt tatctgtata gtaagtgttt ttataataac
     6901 ttttatagca gggtatatac caatgagtaa attaaataaa gaaaatataa tagataatat
     6961 aagaagagaa agtatataga tataaaaata attcttaact atataaaata ttattaaaat
     7021 catttaagtg gtataaaata ttattatatc acttaaatga ttttttattt atataagaaa
     7081 tctaataata aattactaga ggtatttaac tatttagaaa gaattggtat tatataaagt
     7141 aagagaatat ataataagaa agaatatttg attttattgg aaaacaaaag aaaaagaagg
     7201 tgattactat ttctcatata actgcgaaga atatgtataa aagtttagag gaaagaataa
     7261 acaagtttcc acaaggtgct ccaccatctg atacattata caaaatacta aatgtactat
     7321 atacagaaca agaggcgaag ttagttgctc agcttccaat aaagcctttc agagtaaaaa
     7381 cagcagctaa aatttggagt gtaagtgaaa gtgaagcata tagagtattg gataaacttg
     7441 ctagtaaggc tctgatacta gatatagaag ataataaagg gaagaaatat ataatgcctc
     7501 ctccaatggc tggttttttt gagtttgcca tgatgagaac gagacacgat atagaccaaa
     7561 aacttttggc agagctttac tatcaatata tgaatgtaga agaagatttt atcaaagatt
     7621 tattttattc aacagaaacg aagcttggaa gagtatacgt tcaagaggaa gttttaacta
     7681 atgataatga ggttagtatt ttagattatg aaagggctac tcatataatt gatgaatcaa
     7741 ctcatatagg tataagtatg tgttactgta gacatagaat gcaacatgtt ggaaaagctt
     7801 gtgatgctcc catggatata tgtatgacgt ttgacaatgt agcaaattct ttaataaata
     7861 ataaatttgc aagacgtgtg gataaaatag aatgtaaaga actacttcat caagcatatg
     7921 aacataactt agttcaatgt ggagaaaatg ttaggaaagg ggttacgttt atatgtaatt
     7981 gctgtggatg ttgctgtgaa gcaatggtag cagctaaaag atttggaaat cttcatccag
     8041 tacagacaac aagttttata ccaaatataa accatgaaaa ttgtgtaaag tgtggtaaat
     8101 gtataactgc atgtccaata gatgcgataa gcaaggttaa ggaagatggt aaagaatata
     8161 taaaaattga tgaggataga tgtttaggtt gtggagtttg tgttagaaat tgccataaaa
     8221 atagcattat gttattaaag agagatgaaa aaataataac tccagcaaat tcagtacata
     8281 gagcagttct tatggcaatt gaaaaagggc agttacaaaa tttaattttt gataataatg
     8341 ctctggctag tcatagagct atgggagcta tactgtcagc tatattaaag cttgaaccag
     8401 ctaaaaagat tttagccagt aaacaattaa agtcagtata tttagataaa ttgttaagta
     8461 tgaatgataa atagaaacta acttaaaaaa ggcaaagttt tagacttatc tatatcttaa
     8521 taaacttatc atttaatatt taaatttaat ttttacacat ataaaactta taacttaaat
     8581 aaaaaaaggc tatattcaat taatattact tgaatacagc cttttttagt tatgttaagc
     8641 tatttctttt atttgcttaa atgagttttc atttccattt ccaccaattt gtgttacaga
     8701 tttaaatctc atagttttaa atagttcttt ttgattataa tctagtgagt ttcctactag
     8761 cattacagga gatttagttt ttccagccaa aactccaaca gataatccgt ctattaaatc
     8821 atcttgttta ttcattccat ttttagcaac atataaattg tctatcttag aatccttgta
     8881 aaattctttt attacttttg cattagtttc atttctagtg ctacctgata ttctctgtgg
     8941 attttgaagt ttactttcta tatttttaga aactgtatat tctccaccga ttacataaga
     9001 tttatcaatc tttttgtttt taaacaagtt atttatttca gttatattac tattttcatt
     9061 agtaagtatt ataggcatat cattttgagc tgatacagct ccaatgctta ctgcatcggc
     9121 taatcctttt tcgccattaa ctactgaaat ctttgatata ttgctaatat tgttcaattc
     9181 tttagcaatg ttcatagaag tttgatatct atcacttcct gaaattctag atacagagat
     9241 attgtttgat tttatagtat ctaaagattt ttcatttata gaagcctctc caccaactac
     9301 atatacattt ttaactttta atctctttaa ttcagccaaa gttttttcat ttatttgaga
     9361 gcttccagtc aataatatag gagcgttttt cttgtatgca aatggtgttg cagccaaagc
     9421 atctgcaatt gctgaatcgt ttattaaaac tgcattttca gcattttccc aacctgcttg
     9481 acttatctta atagaagttt catatctatc agttcctgta agtgcacttg catttacttc
     9541 atcttgatat gtaacctcaa atctagcatt tggacttcct aagaaaacaa ttacgcctcc
     9601 ttttggcaat ctaactctat tgttctttgt aactaaagaa tagtttacag gaacaccttt
     9661 atcatcataa acagcaaaag atgaattttg aggaagatta acttctattt ttttatttgc
     9721 gatatcgtca ccaatcttat accattttgc ataaccattg gattctagtt cacaagtaaa
     9781 agatttttct gctggcaaat tagttataga atcttcacta acatacgtta gtgttccaaa
     9841 agataaatac tctgtaccat tttctttatg aagtttaatg tcggataaat cacgacctat
     9901 tacaccaggt atttctataa aagcatttga gttattctca tccattattt tagtgttaac
     9961 tatataacct ggagtttcat cagaaagagc aagagttgcc ttcacagaac caaacatata
    10021 gctttgagaa gtatattttt catctactag atagtaatct ttaccatttc tttttttcca
    10081 tgcttctttt acactatttg atatattgtt gtcatctatc ttttgagcta catagtataa
    10141 acttgctgtc tgacctaatc cagggacatc atcataagag ctcatattta aatatgtgat
    10201 attgtttttt tcttttacaa attttagaca gctgttacct ttttcagata caaatctatc
    10261 ttgacctatg tatacgtatt tatcttcagg tccattttct atataaggag aagatactgt
    10321 taaagtacca ttatcattaa catctacttt tatcatattt gaagaagcat aaagaccact
    10381 attttctttt agagagctag gcattttaac ttgttgtggt ttactaaatg ttttatcagg
    10441 ttttatttct ttaattttac ctttttcttt taatgcagat agtaagattt cttgtccaat
    10501 tatttcgtta agttgactac ttccaccaga agaaagaact gcaactgcca tattttcatc
    10561 tggaagaact ataagattac tgtggaataa taaagagtct ccaccttttg taagagcttt
    10621 taaattatac tgattaaatg gataagtgtt gacacaatcc caacctaaac catatccaag
    10681 tatagaatct tctccttcag gccatagacc atttaaatat tctttgtttt ccatagcttt
    10741 tactgaagca ggagaaagaa taccatttga atttttcata aatgtttgtg caaatgtaca
    10801 tagattttct gcacttgaat ataaaccacc tgcacctata gcattaaggt tatcttgcgg
    10861 aactgcatct tcccaataag gtacgtatgc ttttgctagt tttgaactat caaaactatt
    10921 ttctggagtt tttgtatttt gtaagttaag tggattattt atgtatttat caagaaaatt
    10981 agtaaatgac ataccagata ctctttctac taaaatttca gctaaagtaa atccatcatt
    11041 acaataaaca gaaaaagctc ctggtttagc ttttaatctt tgtttttgta attcttttaa
    11101 gaaattatca tgaccataag aatcattgtc tgctaataaa atagtgtttt taaaactact
    11161 tcccatcaac cctgatgaat gatttaataa cattcttgga gtgatttcct tgtatctatc
    11221 atcagccatt ttaaattcag gtatatactt tacaacagga gtatctaaat ttaattttcc
    11281 atcatcaacc aacttcataa cagctgttgt agtaaacatt ttactgatag atgcgatact
    11341 atacatatta tccttattta agtttttgtt atcctgtttg ctgtaaactc caccattacc
    11401 agaaatctca attttgccat tatcaatcaa agcatattga gcacttacag caccatactt
    11461 tgatagcaaa gtttggattt tctctttagc aagagcttta gtttttgtgt aagattccgc
    11521 gtttttacta taatcatgta attctatatc agaactttga tatttttcgg aattaccttt
    11581 tgtattatca gcaaaagtaa tatttggagc agcagtaaat aacatactca atactaatgt
    11641 actagataat aatttagaga gcctttgctt aaacatatta cattacctct ttcccttttt
    11701 aataatttat aattagcata acattcttaa ttattttaat caacagatta ttatcaataa
    11761 aaaaagcttt tataagtata gctttttata taacagagaa aaatataaaa ataatatttg
    11821 ttgttgtata aagaataaag ggtataggta atatataaat aaaatggagg aattttagac
    11881 aatgtataag aatataaata aaaagcaact taaagaaatg atgaaaaatg aaaaggatgt
    11941 tttattatta gatgtaagaa ctaaagatga atttaaggaa tataaaatag aaaatgctat
    12001 aaatatatct ttacaagagt taatcaataa tatagatgaa atttacgatt ataaagataa
    12061 gaaagtagta gtttattgca gaagtggtca tagaagtgtt actgcatgta atttgttagc
    12121 tgaagaaggt tttgagcatt tatataattt aaattcagga ataattgatt atatgagtta
    12181 aataatgtaa gttatacatt aaatactatg tatagctctg cttattaagt aggaatatat
    12241 ctaaatattt ataagataaa tttaggaaag aacgaatttt ttcgtttttt tctatgacag
    12301 tttttgtagt aaatattagt ttttaagttg gaaaaaggta gtagcttttt agctactacc
    12361 ttttaatatg aacttagaat attattaaaa aaatatattt aaagacagaa ttaatttttt
    12421 aatgaccagt taaattacta tcgccgaatt tatcattaaa tggttttata actctattta
    12481 taggtccttt tagaagtaca tttaaacaaa tagacagaat cataaatagt aatagaacta
    12541 gtatatcttt agttagattt ggagcatata taccaccaac tgcttccctt gtagcaccta
    12601 ttgcataggt aaatggcatt atagggttta ttctttggaa gaatgtaggt gtaacttgta
    12661 tagggaatgt accaccagaa gaaccaatct gaacgactaa tagtactatt gcaattgctt
    12721 ttcctacatt tccaaataca gaaactaaag aatacactat aaagttaaat accatactag
    12781 taaacataag cagaactatt aataaaattg gatgttttgc tgttactcct aacaataata
    12841 tatctccagt tcctattata aaaccttgga caagagctat acttaaaaaa gtaaggcctc
    12901 ttccaaagta aatttcataa ggtttatagt ttccatgtac agatgtagac aatagtgctg
    12961 aaataagtaa tataccaacc catgtagaaa gaacactata aaatggtgtc attgcagaac
    13021 cataattttc aattggatat aatttctctg ttttcacctc aacaggttct tttaagaaat
    13081 tagactttgt caatatatca ctttcaagca agctgactaa ttttttcata tcttcaccat
    13141 tactaatttt gcttaaagta tcaatcaaat catccaacat tccttttgct aaaggaagtc
    13201 tttctcttat caatgatata ctttcctgtg catttcctga aagttttaga gaagtagtaa
    13261 gtatttcttc aacctttgga agttttgctt ctgccttatc taaaacagta attatatcat
    13321 ttgctacttt tatactgttt gcaaatatac tatttatagg ttttgatatt tttgagtcaa
    13381 aattatttaa aatatttaaa ttaattcttc caataccatt tgatagactt aaaacattat
    13441 tcaaagcact tatagatggt tgttgtccag atataacttt gtttttaata tcatttaatg
    13501 ttgatataga tgaatctatt ttattgctag agtcttcaag attatctatg acatcatcca
    13561 atctattatt tgatgtaagt tggtttaatt tagttaaaaa atccaccaaa gtatcattta
    13621 aagattgcaa attagaaagt ttttctgata aattatctat caacttaggt acatcttcac
    13681 tgccactatt tactgcatca attaaattta atgtaagaga agaagcagaa gatgaaaggt
    13741 caaccattaa atttaagtca gacttaataa gaggagaaag ttcgtctaaa ttatcatttg
    13801 tatcctctaa gaattttttt aagtcacttg ataacagttt tgtatcattc agagtctttt
    13861 taattgtagg taaatcagat ttaatatctt taactgtatc agataatttt gaagtagcat
    13921 cagaagctaa atcaacagtc ttatttatat ggtcaaatct cttttgaagg tcaataaggg
    13981 aattttcaac ttttgtcaat tttggaagac tgtgttcaat tcctgcacca actccgtttg
    14041 atataccaag aacgatttca ctaactgttt ttactatagt ctgattaacc tgtagttgta
    14101 ttgtagaagc acctttatct gtaatctttg gtgcaactgc atttattttt tcattaacag
    14161 tatagataat ttcccctttt ttaacatcat ctgtaattaa agatgtcaaa tctttcgtaa
    14221 aattttttgg aatcttaagt gatgcataat aagtaccttt tttaacacct tcaagagcag
    14281 ttttttcatc tacaaactgc caacctaaac tcttgttatc tttgagttgt tcaattaatt
    14341 ggtctcctac attaatcttt tgtcctgcta tttcatttcc tttatcttca tttgttactg
    14401 ctacaagcat attagcagtg cttccataag ggtcccaaga tgcctttata ttgaaccaag
    14461 catacagaga tggtaaaaaa gcaagaccta aaactattac aagtacggca taattgccac
    14521 gtatatcttt taggtcactt ttaaaaattt ctaatatatt ttttaaaccc tttgaaggtc
    14581 ttaaattctt gatattattc cagtttaaaa tttcttttaa actattagtt tttttcaaat
    14641 gtctcacctc ctaaaatatt ttgataaaga aaaaagttag atttataatc aattttaaat
    14701 tatattactt tttacacaaa tagtaaagtt aaaattttgt cttaatttta ata
//
LOCUS       DAEPUT010000101        14646 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.104, whole genome shotgun sequence.
ACCESSION   DAEPUT010000101 DAEPUT010000000
VERSION     DAEPUT010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14646
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.104"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(297..1367)
                     /gene="leuB"
                     /locus_tag="KRL22_003295"
     CDS             complement(297..1367)
                     /gene="leuB"
                     /locus_tag="KRL22_003295"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBH1273739.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTRAMGELIVNEI"
     gene            complement(1374..1865)
                     /gene="leuD"
                     /locus_tag="KRL22_003296"
     CDS             complement(1374..1865)
                     /gene="leuD"
                     /locus_tag="KRL22_003296"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBH1273740.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(1880..3157)
                     /gene="leuC"
                     /locus_tag="KRL22_003297"
     CDS             complement(1880..3157)
                     /gene="leuC"
                     /locus_tag="KRL22_003297"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBH1273741.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAKLKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAIIGKISKPSEII"
     gene            complement(3114..4856)
                     /gene="leuA"
                     /locus_tag="KRL22_003298"
     CDS             complement(3114..4856)
                     /gene="leuA"
                     /locus_tag="KRL22_003298"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBH1273742.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(4980..5226)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5374..5820)
                     /locus_tag="KRL22_003299"
     CDS             complement(5374..5820)
                     /locus_tag="KRL22_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273743.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTNESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(5841..6560)
                     /locus_tag="KRL22_003300"
     CDS             complement(5841..6560)
                     /locus_tag="KRL22_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH1273744.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(6678..7952)
                     /locus_tag="KRL22_003301"
     CDS             complement(6678..7952)
                     /locus_tag="KRL22_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBH1273745.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(8152..9519)
                     /locus_tag="KRL22_003302"
     CDS             complement(8152..9519)
                     /locus_tag="KRL22_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1273746.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(9769..10233)
                     /locus_tag="KRL22_003303"
     CDS             complement(9769..10233)
                     /locus_tag="KRL22_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBH1273747.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(10238..10867)
                     /locus_tag="KRL22_003304"
     CDS             complement(10238..10867)
                     /locus_tag="KRL22_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBH1273748.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRIIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNKFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(10901..11788)
                     /locus_tag="KRL22_003305"
     CDS             complement(10901..11788)
                     /locus_tag="KRL22_003305"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HBH1273749.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(11817..13055)
                     /locus_tag="KRL22_003306"
     CDS             complement(11817..13055)
                     /locus_tag="KRL22_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273750.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(13439..14581)
                     /locus_tag="KRL22_003307"
     CDS             complement(13439..14581)
                     /locus_tag="KRL22_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH1273751.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
BASE COUNT         4804 a         2682 c         1490 g         5670 t
ORIGIN      
        1 aaatccctgc aaacttctaa taataaaaat aggctacttc aatatgataa gtttaattta
       61 aagtattatt ttccaaaaaa taactttatc aaaatagaaa ctcaaagtag atataagcct
      121 ctttttcgtt attaaaatag taaaaatata ttttacttaa tataaaaaag agtgtctcat
      181 taactaataa agtttatttt gagacacccc tcataaaaca aattatacta caatagattt
      241 ttactaattc tacaagttat atatttaaat tatattattc aaattaaact ataattctaa
      301 atttcattta ctattaattc gcccattgct cttgttccta caacatttcc cacaccatta
      361 tagatatcaa tagttctata acctttattg agtacacttt gtacagcatc ttcaatacac
      421 ttagcttctt cttctaagtt aaaactatgt cttaacatca tgcttacaga tagaatagtc
      481 gcaattggat ttacaatatc ttttccagct atatcaggtg cacttccatg tattggttca
      541 tacataccaa aactatcttc tctaagtgat gctgatggta acatacctat agaacccgta
      601 atcatagatg cttcatcaga tattatatct ccaaatatat tattagtcac tattacatca
      661 aattggctag ggtcttttac aacttgcata gcagcattat caacatacat atgtgacagt
      721 tctacatctt caaactcttt agctaagtct tccattatac ttctccaaag tcttgaactc
      781 tcaagcacat ttgccttatc tacacttata agttttttat ttctatttct ggctatttca
      841 aaagctctct taccaattct tcttatttca ttttcgttat atatttctac atcataagca
      901 ttttcgatac catcaatgat ttttcttcca cgttctccaa aataaatgcc ccctgttaat
      961 tcccttacaa caacaaaatc aatgcctttc tcaactatat ccgttctaag tggtgaagct
     1021 tcttttatac tttcatacat tgtagctggt cttaaatttg caaataaacc caatgactct
     1081 cttaatttta aaagaccaga ctctggtctt ttatctccct tacatttatc ccactttggt
     1141 cctccaacag caccaagcaa tacagcttcg ttttttcgac aagtttcaac agttttatta
     1201 ggtagaggtt ctccagtttc atcaatcgcg catcctccag ctaatacata ttcacaatcg
     1261 aatctatgat taaatttaca acaaatttta tttagaacct ttataccttc atctataatt
     1321 tccggtccaa caccatcacc ttttatgact gctatattac aattcatact tcactacccc
     1381 ctatttgctt ttattgagtt aattaagcct tcatttaata taatattttg cataaactca
     1441 ggaaatggtt ctgctttata ttcttttcct tttgttatat tttttatcac acctgtagaa
     1501 aaatctactt ctatattatc cccttcatct atgttattgg cagcttcttc acattcaagt
     1561 ataggaagcc ctatatttat agagtttcta aaaaatattc tagcaaaagt agaagcaatc
     1621 acacaggata ctccactttc ttttattaca attggtgcat gttctcttga tgaaccacaa
     1681 ccaaagtttt tagttgcaac tataatatct ccttttttta ccttagaaat aaatttatca
     1741 tcaatatcct ccatacaatg cgttgctagt tctttataat cagctatatt taaatatcta
     1801 gctggtatta ttacatctgt atctatatta tcaccgaatt taaaaacact tccattggca
     1861 atcataaatt ttacctccct taaattattt ctgatggttt tgatattttt ccaattatag
     1921 ctgatgctgc tgctacagct gggcttgcaa gatacacctc tgaatcaaca tgccccattc
     1981 ttcctacgaa attcctattt gttgttgaaa tggatttttc tcctgctgca agtataccca
     2041 tatgtccccc tagacatgga ccacaagttg gtgtagaaac tgctgctcct gcctctataa
     2101 aagtggtaat ataccctttt tctatagctt caagatatac tttttgagtt ccagggaata
     2161 tcataactct aactccatct gctacttttt tgcctttcat tatctcagct actacttcaa
     2221 ggtctgatat tcttccattt gtacaagagc ctattacaac ttggtctatc tttatatcct
     2281 tatctatctc atctactgtt ctagtatttt caggaagatg aggaaaggct actgtttctt
     2341 ttagtttggc taaatctatt tcgtatactt catcatagac tgcatcttca tctgcttcat
     2401 atatatttac atcttttgtc atagttgaac acttatgtga atttatatat tccatagtct
     2461 tatcgtctac tggaaaaatt ccattttttg ctcctgcttc tattgccata ttacaaatag
     2521 taaatctatc atccatagat aagtattcta ctccatctcc acaaaattcc attgacttgt
     2581 aaagtgctcc atcaacacct atctccccta ttatatgaag tattatatct ttaccactta
     2641 tccatttatt tggtttattc ttcaaaacaa attttattgc tccaggaacc ttaaaccaac
     2701 attttcctgt agccatacct gctcccatat cagttgaacc tacaccagta gaaaatgctc
     2761 ctaatgctcc atatgtgcaa gtatgagagt cagcacctat aattacatct ccagcagtta
     2821 ctataccttt ttcaggaaga agaacatgct ctattcccat atctcctaca tcaaaaaaat
     2881 ttacaactcc ttttgatttt gcgaaacttc ttgtaaattt acattgttct gcactcttta
     2941 tatctttatt aggtgtaaag tggtctaaaa ccatcactac tttagtctta tcataaacat
     3001 cttcaattcc taatttttca aattctctaa tggctactgg tgatgttata tcattaccta
     3061 aaactacatc taaatctgct tcgattaatt gccctttctt aacttcattt aatttagcat
     3121 gtttggctaa tattttctgc gtcatagtca tccccatttt ttatttcctc ctcaatataa
     3181 cttttattta ttgcattcat aagtgcatta atagctgctg tatttatgtt ttccgatata
     3241 cttacaccaa aatagacttc attattgtgc tctattccta cataagctac ccctcttgaa
     3301 tgtgaccctt cctctaatgc atgttcccag taatatctaa atttataatc tttcatgcca
     3361 cattgcttta gtgcattatt aaatgaatct acaggtccat ttcctatacc aacaatcctt
     3421 tgttcatttc ccatataact tattcttgca gtcatctcaa tcatattagt atcattagaa
     3481 tcatcatttt catagtttaa ttcatccatt gattttattt tatacttctt aactttataa
     3541 gggctctcaa cttcaatata ttctttctta aacaaattaa atattgcttc actactaagt
     3601 tcttccccaa ttctatcaga ttccattttg actacatttc caaaatcaga atgcatattt
     3661 ttaggtatca taaatccata atctgtttcc attatataaa cagctcctcc ttttccagat
     3721 tggctattta tccttataat ttctttgtat tctcttccaa tatcatgagg gtctattggt
     3781 aaatatggaa cttcccagta atcattatct ctgtttttca ttgctatcat gccttttcta
     3841 atagcatctt gatgtgaacc tgaaaaagca caatgtacaa gattacctgc atatggatgt
     3901 ctatcatgta ccataagttt tgtacagtct tcatatatac ctattatctt atctatattg
     3961 ctaaaatcta gctctgggtc tattccttgt gtataaagat taagtcccac atttactata
     4021 tccatattcc cagttctttc accatttcca aatagtgttc cttcaagtct atcggcacca
     4081 gccaataatc caagttcact tgcagccgta caagttcctc tatcattgtg agtatgcaaa
     4141 cttagtataa tagaatccct acaacttata tttttacaaa accattctat ttggtctgca
     4201 tatacgtttg gtgttgccat ttcaactgtt gatggaagat ttattattac ttttttttga
     4261 ggagttggtt tccaaacatc tatcactgcc tcacatattt caagtgcata atccatctct
     4321 gttcctgtaa aactctctgg tgaatattca aaagtaaatt ctgtttctgg atattttttt
     4381 acttcttcat taaataattt tgctccttca actgctatat ctattatttc ttgtttactc
     4441 atattaaaaa ccacatctct ttgaagaaca gatgtagagt tatataaatg tataattgct
     4501 tttttacatc cccttattga ttcaaatgtt ttttctataa gatgagccct agattgtgta
     4561 agtacttgta tagttacatc atctggaatc atattctcat ctattaattt tcttaaaaat
     4621 gtatactctg tatttgatgc tgatggaaat cctacctcta tttctttaaa tcctgtatca
     4681 ataagcattt tgaacattct gactttttca tttacactca taggtgttgg cagtgactga
     4741 tttccgtctc ttaaatcgac actacaccaa attggagcct taaatatttc attatctggc
     4801 catttacgat ttactatttg cattttatca tattttttat actttccaca cttcatgtta
     4861 tttccccctt tttctgtttt ttgtatttag tatacctcat atcgacgcaa tcctgcacaa
     4921 ttcataagga taaatgtcaa ttttatcatt agaataaaaa aaacctcatc tctaataaaa
     4981 ttagagacga ggttttgctc gcggtaccac tctatttagc tttctaaaaa gctcccttag
     5041 taatagccaa tacaataatt ataatgacta tatttcctat aacgtggaat tactccgatt
     5101 attctaagat ttaaatctta gaaaacagct cctagacaag ttcagaacta tcaactacta
     5161 aatcacacca tcctttagct ctctgaaagt ttcattgttc ttactacttc tattcatcac
     5221 ttttttaatc atttaaattt tctaaatatt ttgatttaat agttattata tacacattaa
     5281 aatgtattgt caacacaaaa aataattatc tcaatttttt atttttgata agcaattcta
     5341 taaaacatgc taactattga aaacagtatg atattatgcc ttaaactttt tcatcttttc
     5401 atctatgata ttcaataatt ttttttcatc ttccaaactc aatgccctta atctaatttt
     5461 ataattagat tcgttagtgt atatatttaa tatatttttt actacttcta ttttttctat
     5521 tatcttataa ttaaactttt gactttgttt agattttata ctgaatatac attgattatt
     5581 tattaatatt gaatgattat cgagagtaat atatactttt ccctcatatt tatttgaaaa
     5641 atcacgacct tgtttaaata gaaaaactgc tgttattata cataaaatat ataatattgt
     5701 cgttgaatat ataaaaattg tagctaaaat tataagtgct aaaaccatat atatagtcat
     5761 tcctttttta aaataaccat tgtcataata attcatatag ataaacttat ttttactcaa
     5821 attttttcac tcccaagatt ctaaaaattt atatcaaaaa attctataat ttcatcttca
     5881 tgataattta tgactaattc atctggaaaa tctactgctt ctaaaacttt ttctgcattt
     5941 tcaaattctc ctatagaata acatatatga gagtcagtac caagaattac tcttgcacca
     6001 tatgttttac acaatgtcaa catatgactt acattttccc aagtacccgt tctatgagag
     6061 tttgaactta atgatgaatt atttatttct aaaaggatat ttttatcttt agcttttttt
     6121 actataggtt cataatctaa aggataccta ctgtcatctg gatgtccaat tatttttacc
     6181 ttaggtttat ccataacttt taaaatagca tttgtatttt cttcttttgt accagaagct
     6241 atacaaggtc tatgcaaact tgcgattata taatccaaat gttgcaacat atcttcttga
     6301 acatctaaat taccattata atccattata tttccttcta ttcctctaag aatctttacg
     6361 ccttgcactt cacgtggaag caaatgcaaa ttataaaaat agaatggatg tggtcctcct
     6421 ggcatattag gtccatggtc tgatattcct aagtatttta tattcttctt actcgcctct
     6481 tcgacatttt ccttgaaagt actatgtgca tgtccactta ttagagtgtg acaatgtaca
     6541 tccataatag actttttcat taaatttcct cctaatattt tacataaatt cgtgaaaata
     6601 gctaaagggc tatttcaaaa ctaaagctgt cataatagac agtgtaacgt tttaaaacag
     6661 ccccattttc aattatttta cacttctaaa tctttaaatt tatctttaaa taattctcca
     6721 atacttccta aagattcctc tacttctagg tattctgtta tatcctcttc tggctctcta
     6781 gttgcttctt ttattgaaac caacattctc ttagtctttg gtttaaaatc aagaatctta
     6841 actttaacct catctccaat attaacaaca ttagtaactt tagccactct agtatcactc
     6901 aattcagata ttggtaaata cgcatctaca ccttctttaa tttgaacaaa agcccctttt
     6961 tctattattc taagaacttt agcattgaca acatcatcaa tttgtacttc ttttgctatt
     7021 aaatcccaag ggtcattatt tatgtctttt aatgccaagg caattttttt agtctcttta
     7081 tttacatcca acacataaac ttctacttct tgtccctctg aaacaacatc ttcaacactt
     7141 tcaactcttg tccaagctaa attatttata tgtgctaatc cttcaatccc accaatatcc
     7201 acaaatgcac cataaggcat tatctttgtc accttaccat ctcttttttg tccaacttca
     7261 agagaattaa ataagtcttc tttagctgct ttgatacgag ctttttcttc ttctctttct
     7321 tgcttaattc ttgctctttc agcttctttt tctgccttaa tttgagctct tctttcttct
     7381 ctctctttat ttatacgctc ttgtaataca tctctatgag atgctacaag tctatttttt
     7441 ctaacatcca attcttttat ataaacttct aagttaagac caacaaattt agatgtatct
     7501 gtaataaatt ttgtatcaag ttgagaaatt ggtataaaaa atgtatatgt attgtaatta
     7561 gcaaatacac ctttatctat attcttttca acatttacag ttattattct atgttcatca
     7621 taagcctttt gtaactcggc aaaatcattt cttttgtcaa gttgtaattt agataaagtt
     7681 attgtaccat ctttttgaga tacttttgtt attacagcag ttatttcatc acctatgtgg
     7741 tatatatctt ctatatattg atttttttct atgttcaatt cacttatagg tattattcca
     7801 tcaaacccat agtctaatcc taattgtact tcatcatttc tcactgcagt tatttttcca
     7861 gttgtcaatt ctccaacttt cactttgctg aatacttgtt cttgctggtc aagtaattct
     7921 tgcattgtta aatcattttc cattataaac atcctttcct cttattgatt atcatatctg
     7981 taaatattat accattaata ttgcaaatac ttacattttt cttactataa tttttaaaat
     8041 aaattcaact tcatatattt atacattata gaaaatatct tattaaatta aaatacaaat
     8101 tctaattttt atctaataaa atattttcat aaaaaattta tattgtatat cttattcttt
     8161 tattgcttta ggttttgata gaaaacattt ataaaatata aagaaagaaa ttgctgttat
     8221 agtagcagct gttatatctg caactggctc tgctaaaatt actgcaaaaa gtttttcatt
     8281 aaagaatgtt ggaagtataa atattaaagg tattaaaagt acaatctttc taagtagagc
     8341 taaaaccaaa gatattgttg cttttccaag tgctaaaaat gtctgttgac aagctatttg
     8401 aatcccaaac ataaaagcac cagcaaaata tatttttata ctccaactag tcatactaag
     8461 taactgcgga ttcttattaa atatactaac aaaaaatgca ggaaatatca ttaataaaag
     8521 ccataaaata gtagaatatg taaaacatga caacaaacac aacttaaatg tcttttttac
     8581 tctatcaagt tgacctgaac cataattata acttattatt ggttgtgctc cttgtgtaac
     8641 ccccatatta ggaagcataa gaatttgcat tatactgctc attatagcca ttgaacctac
     8701 tgctaaatct cctccataca tttgtaattt actatttaag gctataagta ctaaactttc
     8761 tgtagattgc attataaatg gagagattcc caaaccaagc actggtaaga tgatacttgc
     8821 ttttggtatc atatacttct tttttatttt aagtatactt ttctttccaa agagaaacat
     8881 aagtacccaa atagcagaaa cgccttgtgc aattatagta gctaatgcag ctccttttac
     8941 acccatatta aagccaaata taaaaatcgg gtcaagtatt atgtttatta aagcacctat
     9001 agcaactgtc atcattccag ttgtagcaaa cccttgggta tttataaaag tattcatacc
     9061 cattgaaatc tgaacaaaca ctgtacctat taaataaata tttaaatagt ccattgaata
     9121 tccaattgta gattcacttg ctccaaacat ccaaagtaaa ggctcttttc caatcttaaa
     9181 acctatagtc aaaagtattg ctaaaatcac cagtacagaa aaactgttac tcattatttt
     9241 ctctgcctca tcattgtttt gctcacccat ttttatagca gctaatggac ctcctcccat
     9301 accgattaaa taactacatg cagttattat aattattatt ggaaatgcca ctccaacacc
     9361 agccatagca acttctccat tttccattct accaataaaa atcctatcga ctatgttgta
     9421 taaaacattt acaatttgtg cgataatagc aggtgtagca agtttaaata ataatttacc
     9481 cacactttca ctacctaagt tagtgtttga attttccatt ttaaaacctc ctcaatccaa
     9541 taattaaaat gtatcactaa aattttattc tatataaaaa tttcatttta ttagcagaca
     9601 aatttagagt actttcccta caagtaatac tatactatat ttcttttgcc atagtaaaca
     9661 ttttagaact aactgaagtt aaatacttta tctcattttt tatttattat taaaaatttt
     9721 tcacacatac tcataaaaaa actatccaag tatattactt agatagtttt atattatatg
     9781 taaagaaaga gctgaaacta taacccctga taacaaattg ccaagaaata ctcccataaa
     9841 agcatctttt attctcattt ttaatatgga agctatagca gatgcagtcc acgttcctgt
     9901 agttggcagt ggtataccta caaatagtat tataccaatt atcgaaacac tttttaattt
     9961 cttcattctt gagtttattt ttctatcaat tacatcagca atccctttaa atagtttctt
    10021 ccctcttaaa aattgtaata catgtctgaa tgtcaatatc aagggaatcg ataccaatgt
    10081 agaacctatt acactaaata cataaaccca tataggattt aagcccattg caatacctat
    10141 aggaatggct cccctcaatt ctgttacagg aaccatagat aaaattaata tgtgtaaata
    10201 tcccaaacta ttccctccta ttctaagtga cattaagtta tgaatttatt tgctctataa
    10261 cctcaccatc ctttttacta actaaaaatg catttttagt caatgaaagc attggtaaat
    10321 cactcttaga gtctgaatat gcatatgaat tttcataatc aatctctatc ccaagtttac
    10381 ctaatacagc ctttattctt tttacttttt caattccctt acagttttct ccaatgaatt
    10441 tatttttata tcttgaattt tcataaaaaa actccgtgcc tataacctcg tctgcaagac
    10501 cataatactt aaaatatttc atatatgcat atggagatgc agttatcata attataacat
    10561 tatcttcttc tttatttttg taaataacct ttttcataga ttcgttaatt tttttcatta
    10621 tgcaatcatc aaaaaacttt tttaaatctt cttcactaaa atctactatt ggataaaaga
    10681 ttgcctcttt tgccttcttc aatggtatta ttctaattaa atacataaat agaataaaaa
    10741 taatgtatgg taactttata atagttttaa aggttttatt ttttaaagag taaataaaaa
    10801 aatctatcat gctatcagta tttataacag tataatctac atcaagtaat aatacacttt
    10861 ttttcataag tatttcccca tcctatcact aaaaatatca ctaaaaaatc aatattatta
    10921 aacatgtaat tatccataag attacgttta tttttaaagc attatctttt aagacaatat
    10981 cagtaggatt attttcattt gtagtgttaa ttatataatt atatctaagt acaccataaa
    11041 ctacaaatat tgttgtaaat atcatatgtg gcttttctgg attacttgta gaatacaatg
    11101 cataacatac aattgtagaa cttaatataa ctatcatcat ttgatttaga ttttctatgt
    11161 cataatcttc caatattttt ctatgttcaa ctgcatcatc tcttagagtt tctatttctt
    11221 ttttacgttt tccaagagct aagtacagag ataagaaaaa tgtacataaa attatccaat
    11281 ttgataaact aacacttatg gctacacatc ctgcataaac cctaagtata aaaccaagag
    11341 atattgaaaa cacatctaat agtattatat tctttagttt aagagaatat aatatattgt
    11401 ttatcaaata gagactgaga attatagaaa gattaaaact aacaactgtt gataaacaga
    11461 ctgaaattaa agctaatact acaaatagta tattagcact ttttttgctt attcttccac
    11521 ttgccactgg tctattacat tttttaggat gttttttatc tttatccatg tctatagcat
    11581 cattcagtgc atatactgat gatgacatta gacaaaaaca cacaaacgca ataaacgtat
    11641 ttaaaaataa atttatattt agtatgttgt ttgaaaaaat tatagctgaa aatacaaaga
    11701 aattctttat atattgcttt attctcatta actttatata atctgaaatt ttagtaagaa
    11761 gccttatact tgtattggtc tgtttcataa acttactacc ctttcaatat tattttttaa
    11821 acaggatatg attttatccc tatgtttaaa atttctataa atccattgac attactgatt
    11881 actatagtaa ccaataacag cgatagaaat atattataca tattcttttc attttttcta
    11941 agcgctttcg taaagtaagc caataaaatt ataactgcaa aactaaaatt tatagccata
    12001 atacttgaat tgactagatt atatcctact ataccatgta aagttagatt gaatataatt
    12061 attcccatac atagcttagg aactcttttt tctgaatttt caataactga taaaacacaa
    12121 aaacataaag ctaataatgt aagaattact ggtattgtag caacttctcc attttgcaaa
    12181 aataaccctt ttttaatact tgctccagga aaataaaaaa ccgaatacaa taatctctct
    12241 ataatcattg caatcttttc caaaattggt tctccactta taaatttcgt atcatactgt
    12301 attacatttc caaggttcat aaaactctca taagactttg ttgaaactac acaaatatat
    12361 gccattagga taaatgtaat taaatgtttt aacatttttc ctatttttaa tttaaactca
    12421 aatatcatat taaaaaaata caaatatata ttactaatag ttattccaaa tagaggaata
    12481 gctgctaatt ctactaaata agaatttttt cctttcatct tatttgcaat aactatgaaa
    12541 aatattaatg aaaattggct atatataaat ctctctacat ttaaagtcat aaataactgt
    12601 ggaaaagaaa atatcattat catagtaagt aaaattaaag ttaatctctg catttttatc
    12661 tttttaatat gattaaagac taaagttatt gacatagcac tagttattat ttgtagacaa
    12721 attagtccaa acccataggc actattaaaa tctgttgtcc caggatttgc tattgaagta
    12781 caaaataggt atattggata tgcaaaaatt gatataattg ctgaaaacaa tatgtgctta
    12841 ctattgtctt gacttatagc aaatacattt aaattgaata aaactcctgt atctgtatct
    12901 aacaatacat cataagtatt gtttaaatca taaaatatag tagtcttaga aaaaaatatc
    12961 ttagttatta ttaagtaagt tattacaact aatataaaca aaaacatctc gtttttatat
    13021 tttaatattt tactcatcaa tatatcacca tccattcatt atataggatt tgctgacacc
    13081 tacaatttat tccttatatt taatagccat cttcataatg ttcttacttg ttttattgta
    13141 attgaataac tctttattta caaccacaat atttacttta ttgatgttat aatcagtcaa
    13201 gtattgttta tataacatag attagtgttg tataaaatga gaatttgtaa gcaatattaa
    13261 tgtaaaatat ttgaaaaact ttatataaaa atatacaatg ttgcttatgg aattaaacta
    13321 taacaaatta aagcataatt taaggagaca aaattataat ctgtctcctt aaatattaaa
    13381 actatatttt aaaacattac taaatactat acaaatttca aatatagtat aaaattaatt
    13441 agactttaac actattagct ccatcttctt cccatttttt aatttctttt aatctatcta
    13501 ttataggtaa atgctgagta cattcaactt cacattttcc acaagatata cattctttag
    13561 cttttgcctt actattcatt gtgtaattcc aatgtcctaa gccataaact aactttgtca
    13621 tttcttcatc actcttttta aacatctgct tttcattata aaaaagcata taggctgggg
    13681 tattaatacc ttttggacat actttacaat aaccacaacc tgtacatatt tcgttcatat
    13741 tcttatttaa tctagtctca atatcatgta tatcctcatc tgaataaatt ctattttcgt
    13801 ctgcaatttt acatgcatca tctatatctt gttttttatt aaaccctatc aaagatatac
    13861 ttatttgtga aattcctatg ttgaatctta aagctgattc tatagtactt tcgccatctt
    13921 ttgatagaaa agaaagttct ttattatact ttggaatagt tccaccactt aatgggttca
    13981 ttgccacaac accatatcca ttatcaacag catatttggc accttttagc ctatatggaa
    14041 agtttaatat atttattccc atagttacac cttcaaactt attttcactt agaatatcta
    14101 taacctcatc ccctggttga tgagatgaaa atactatatg gtctatcaat ccttcttctt
    14161 tacatttcaa taatccttca tattgacctc caggtctcat tgctagttcg taatgttcca
    14221 tctttctaat attccaaaca tgataaaaat ttattttaga tacgcctaat cgttctattg
    14281 atttttttac agcctctata gctttttctg atgtatcaca tgcttttggc ttttctttag
    14341 ttgatacata aaaatcggtc ttaccttcct ttatcatttg tctaaaggct agtccaaata
    14401 tatcttcact tctgtcatca caataccctg gtgctgtatc aaagtaatta ataccttttt
    14461 catacgcata tttgactaaa tcagcatttt cttgattact tttttctaaa tcaaacctta
    14521 atcctccata gccaactact gaaaccattt tccctgtctt tccatattca acgtatctca
    14581 ttgtaaattc ctccttagat atattaagac ttaatttctt tatagaaaat attataccat
    14641 aaataa
//
LOCUS       DAEPUT010000102        14004 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.105, whole genome shotgun sequence.
ACCESSION   DAEPUT010000102 DAEPUT010000000
VERSION     DAEPUT010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14004
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.105"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            402..1805
                     /locus_tag="KRL22_003308"
     CDS             402..1805
                     /locus_tag="KRL22_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1273752.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            complement(2206..3228)
                     /locus_tag="KRL22_003309"
     CDS             complement(2206..3228)
                     /locus_tag="KRL22_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1273753.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPKLI
                     ERGSTL"
     gene            complement(3263..4861)
                     /locus_tag="KRL22_003310"
     CDS             complement(3263..4861)
                     /locus_tag="KRL22_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBH1273754.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVVLKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            complement(4903..6168)
                     /locus_tag="KRL22_003311"
     CDS             complement(4903..6168)
                     /locus_tag="KRL22_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1273755.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            complement(6312..7724)
                     /locus_tag="KRL22_003312"
                     /pseudo
     CDS             complement(6312..7724)
                     /locus_tag="KRL22_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
     gene            complement(7762..8769)
                     /locus_tag="KRL22_003313"
     CDS             complement(7762..8769)
                     /locus_tag="KRL22_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH1273756.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            complement(8966..10288)
                     /locus_tag="KRL22_003314"
     CDS             complement(8966..10288)
                     /locus_tag="KRL22_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273757.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIDTYDKAMMKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDVCCC
                     ITGLEEAYHIMKKDNIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIIVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPTVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAT
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            complement(10646..12286)
                     /locus_tag="KRL22_003315"
     CDS             complement(10646..12286)
                     /locus_tag="KRL22_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBH1273758.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            complement(12391..13047)
                     /locus_tag="KRL22_003316"
     CDS             complement(12391..13047)
                     /locus_tag="KRL22_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273759.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDNNKTKE
                     "
     gene            complement(13073..13774)
                     /locus_tag="KRL22_003317"
     CDS             complement(13073..13774)
                     /locus_tag="KRL22_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBH1273760.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKEALKEASNLGIE
                     KKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILS"
BASE COUNT         4762 a         2633 c         1668 g         4941 t
ORIGIN      
        1 aacaaatcct ataattatat tctaatatac tacctactac tttgcgctac aacaatttct
       61 ctatttatat gatttgtaaa atatagtaca acatttttta tcattttcat ttcaactaaa
      121 tttgtaatat tttattcaat acttaataaa tacttaatca atacatgctt tataatactt
      181 tactcaatat ataatcaata cataatttat aatttgtaat actttattca atacataagt
      241 agaaatctct atatacataa attcattttt tcatacatct tacaaattta tttttattta
      301 gataacatgt atattttttc catgaaaaat aaataataaa aaatagtaaa tatggaaaat
      361 ataaaattga ttaacaataa ttaattacct gaggtgtgaa tatgaaaatg ctaaacaact
      421 tttttaagaa aatcaacaat ccagctcctg tctttgcaca gacaaaaatg gaaagagata
      481 atcaaacaga tgattcactt tctacaaaac caaagactac atttagagac gttgctggat
      541 tagacgaagt aaaagaagaa ctatttgaaa tagtcgattt tatgaagtca ccacaaaaat
      601 atcaaaaaat gggtgcaaaa atacctaaag gagtattatt ttatggtcct ccaggaacag
      661 gtaaaaccct acttgcatct gctgtagctg gtgaaacaaa ctcatcattt ttcaatgtta
      721 ctggttcaga gttcgttgaa aaatatgtag gtgtgggagc aaaaagagtt agaactctat
      781 ttgaaaaagc tagaaaagaa gctccaagta taatatttat agacgaaata gatgctgtag
      841 gagcaaagag acatcttgaa agtaacaacg aaaaagacca aacactaaac caacttttag
      901 ttgaaatgga tggatttaat aaagattcca atgtattaat aataggtgct accaatagac
      961 ttgacttatt agatgaagct ttacttagac caggaagatt tgacagacac attcatatag
     1021 gtgcaccaaa ctatcacact agatttgaaa ttctaaaggt acatacagat gacaaaccta
     1081 tagacaaatc tgtaaatcta gaacttttag ctaaaaaaac tcatggtttc aatggggctc
     1141 atctttcaaa tatagcaaat gaagcagcta tatttgcagt tagagatgac agtgagtgta
     1201 ttacatcaga acattttgac aaggcacttg aaagagttat tgcagggcta gaatctaaaa
     1261 actctgcatt ggttgaaaaa gagaaaaaaa tagtagcata tcatgaagct ggacatgctc
     1321 ttgtaagtga tatagtagga atttgtccta tacaaaaaat atctatagtt cctagaggac
     1381 aagcattagg ttatgttctt caattacctg atgaagatag atatatttat actaaggatg
     1441 agttgattgg aaaaataaaa atattacttg ctggaaaggc ttcagaagaa ttaatattta
     1501 atcataaatc tactggtgca aaggacgact taaagaaagt cactgaaata gctaaccaaa
     1561 tggtttgtga atatggtatg agtaacttag gatttatgac tattgatgga aatgataaga
     1621 ctttcttatg tgataaggtt caaaaggaag caaatcgtat agttgaaatt tgttataaag
     1681 agactttaga gatgttaaag gataatcttg aagatttaca ttctgtttct aaattcttat
     1741 ttgaaaaaga aactatgact catgaagagt taaaagattt gataggaaaa gaagctgtaa
     1801 actaatatag ttttaaaaat ttgaggctgt ctcaaaatag agataagcct ctttttattg
     1861 ttaaagttat aaaaatacat ttgattttat acaaaaaagt gcctcataaa ctaaaaattt
     1921 cattttgaga cacttacata ttttaattac atattttaat tttgtctatt tacagaatat
     1981 tatatctaca taaaactaaa ctgatgtaaa cttaactacc tccagtaatg tttgaagtgg
     2041 tataaaagct agtagcctag tttctacact tataatttat attttacata actaaattta
     2101 gtagattttt atactcacaa tttagaacga ttgaaaactt aaaaatttct tatcagatat
     2161 ctacaactta attaggtatc taccacttaa ttaaatatct accacttaaa gtgtagaacc
     2221 tctttcaatc aatttaggtt ttaacatttc aacaactgac tctggatttt cttcatttaa
     2281 taaggactta agtatgttaa ttgttttttc aatcaacaaa tctagtggct gtctaatcgt
     2341 cgttaaatta taactcttcc atgaagccat ttgaatatca tcatatccta tcactgataa
     2401 atcctctggc accctcaact tgtactcaaa ccttgcagca tccattacac caatagctat
     2461 caagtcactt gtgcaaaaaa ttgctgttgg aggatttgat aatgctaaca ttctcttacc
     2521 tgcttcatat ccagaatcat aatcatagtt tgcagattct tctttaaggt tatgaatccc
     2581 actttgtctt aacttagaat aaaatccaat tttcttttcc atttcttcac ttgtttctct
     2641 cgtaaattga atatatccta tattcttatg acctttctta agcagatatt cagcagccat
     2701 gcccccacct tcaattgggt ctacatagac tgtacttatt tttataccag gtataaaacg
     2761 attaaaaaga atcacaggaa tattgttttc ttcacaagtc tcagccatca ccttattcat
     2821 ggccgaagct gtaataatca cagcttctac ttgaaactga attacttttg aaattatact
     2881 atctatactt tgttgtctag gaactttaaa aacgagacac tgtttaccta tctcttgaat
     2941 tttttctaca aataaattga taattctatt gtaaaatgga cctagactat caccaactat
     3001 caatcctata acattagttt ttccactaat cattccccgt gctaccaaat taggaacata
     3061 tcctatttcg tttgctacac gaaaaattct ttctcttact tcaggtttta cgccctttcc
     3121 atttgcacta ccaaatgctc ttgaaacaga tgattgagat actcctgcca atcttgcaac
     3181 atcttttgag gtagccgatt tattataatg aactttcttt tgattcattt agtatttctc
     3241 cttaaatatc tagtatttct tcttaaaatt gtatcaaaaa taatataata tattggataa
     3301 taaaaaaagc taatacaatt agttcttgtt tacctaaaga aaatggcact atagatactc
     3361 catctacttt atccattcct tgagaaataa ggtgatttct cataccaaat gcagtgtatt
     3421 ttttaatatc atctgcatta tgatttttct ttaaaacgac actaaaaata tatccaaata
     3481 tcaatgttat tgtagcacct attgctggat tccacaacca actcacatta tatttattag
     3541 aaataaaaaa tcctaaaact aaccctacaa taaaaccaat agatactcct ttatcattag
     3601 ctttatatgt aaacattgct agtacaaatg cacctgtagc tggtccagca aagtatgaga
     3661 tatagttacc aacaaggtca agaattgatt tgatgcttcc tccaaatccc ataataataa
     3721 aacctgtcat aacaactcct ataactacag ttataatcat tgtaactttt aatgatgatt
     3781 ctttgttatc ttttttgaaa taaaactcat aaatatcctt cgtaaaaaca gttgtcatac
     3841 tgtttaatat agagtcgata ctagacattg ctgctgcaaa cacacctgca ataataattc
     3901 caatggctcc tactggaagt tcatttaaaa taaaagtaat cattatttca tttgaagttt
     3961 caaatgtcct tcccccataa aaaacaaata aaattactcc taccaatagc ataaagtagt
     4021 aaactaaatt cataacaaat gcactaacta caaaagaatt ttttgcacat tttaaagatt
     4081 tagatgttaa aactctttgt acttgagatt ggtcaaaaca aaagtatctt atccacatta
     4141 cagttccacc aattaaagta gcccaaaaag tatttgtcac tgaaatatcc ctactgaaat
     4201 caaatgtatt taattttcca ctctgttgtg caatttgtaa tgtatcaaag aaacttagat
     4261 tcattccttt taaggctaca ataattacta taaatacagc acttattact actatcattt
     4321 gaatactatc agtccatata actgccttaa tcccacctaa tagagtgtat ataattgata
     4381 caagtacaac tattgggact aaagcataaa gtgaccagcc agtaatcatt tgaataataa
     4441 gcactggaat atataccata gaactagctt gaatcaatga attaataaaa aattgaataa
     4501 tagttaatcc tcttgaataa tttcctaaac gaagtcccat atattcatat atagaggtta
     4561 tttttaattt atagataact ggggtggtaa tgctcagtgc aaaaaatatt gctaaaggta
     4621 ctgtaatatt aaccattact ggatacattc catctacata tgcccatcca ggaccaccta
     4681 taaagccatt tgcactaatc atagtagctg caactgataa agcaattgga atccatggca
     4741 ttgacctacc tgccaagaaa taatcttctt gatttttatt atcttttcct gaataataac
     4801 caataactaa cattaatagc aaatatccta ttataataca tacatcaatt gatgaaatca
     4861 taagccaccc ctttctaagt aacaaaataa attcctagta ttttattttt tattatttaa
     4921 cgtctctggt aagaataacc atacaatagc acctgctaca aagactgcga ttgatatgta
     4981 aaagatagtc atcataccta aagtaccaga agctgtacca gctatagcag gtattgcaaa
     5041 cgtagatata atccttcctc cattaaatga cataccagat gacaacgaac gatatttact
     5101 tgggaacaac tctgtgtagt atgctcccca tgctccagaa tatccaacag caacacctag
     5161 taatactgat atcatataga atgttgttgt attatctcca cctaattttg tatatataaa
     5221 aacaaatact gctgctaatg ccatacctat aaaaggtatt tttcttccaa atttatctgc
     5281 aattgaaccc cagaataaat atcctactaa ttgaccaatt ccttgtaaac tatatataga
     5341 cccagccact gctgctgaca ttcctattcc tgtcactagg tatgtagttg cattatttga
     5401 aaatgctgaa tatgctgtaa aatttgcacc tgataaaaga atcgttccca atccaatcca
     5461 taagtatttt cccttataca tacttatata gctaatcttt tcaccagttt cttttccctt
     5521 tttaactaat tcctttgtat actccaaatc atctggcaca aagaagattg ctaagatagc
     5581 tccaactata ggtggtataa tcgcagtata catcaatatt tgccaatttg catcacctaa
     5641 aacgccatat actttcccac caaaaatcat tgctaatgaa aataaagcag ttaatatagc
     5701 agctaactta ccacgatatt tacttggaaa catatctgca actaaaggca tagctgttcc
     5761 aaatacgcct cccaacacta ctcctgtaca caaacgtgct attttccata acataatatt
     5821 tgtaggagat aacattggta taaatgttgt caatccaatc agtaaagcaa cgctaattaa
     5881 agtcctcttc ttcccaattt ttgtagaaat caccccaaaa ataaatgtac ctggaattgt
     5941 accaaaagac ataactgcaa atatttcttc tgtttgtttt aatgaaaaac caaatccccc
     6001 atctgctaaa gcataaatca ttgttggttt aataaaagta cccaccataa aattgtagca
     6061 ataaaaaaag tatattaaag caattgaaaa aaatgcaatt cctcttttta ggtttgaata
     6121 gtcttttcct aatatgatat cattttctat ttcaaccgtt gttttcatat ttttataatt
     6181 ccccctttta aatttagtca taattttgct aaaagtttaa acatctattt ttcatataca
     6241 ttccccactt aaattttata aagcaatact tccctatata cattttaaaa ctatttatac
     6301 tctaaacagc tttattcttc tactcccata tacatttgtt ttaatacatc cataccatca
     6361 aaagttatcc actcctcctt tactttacct tgtagtatat gataatgatt gattcccatt
     6421 acttctatat gctttccaga aggctgtcca aaaaatccta taccttcatt tattccacgt
     6481 aatctccatc ttacagatac atcataacct tcattttttt ctctttgatt acaagttact
     6541 ctttccactt cataacttcc atttggaatt gatgcaagta aacttacaat cattccttga
     6601 atctcatcat aaccatttaa atctttatca catataaaat gtactactgc attatcatga
     6661 tagtattttt taacttcatt tatatattta taattataaa tacggcttgt catttcaagc
     6721 atcatttcgc caacagaatc atcttttgct tgatacttag ttggcataaa ttgaccatcc
     6781 atagattcac agataccata agttgattgt aaactaagca ctttagattc acttgccttt
     6841 gccatactct ttgctacttc ctgagggttt aatcctaatt gagtaacaat ccataaatta
     6901 tctctaacca accattcttc gtggattcta ttgttagttg tggcacaatc aattacagtt
     6961 ctaaagttta tttttctacc tgttgctggt ccaaaattac tatcacctaa gttagttgct
     7021 gtagacaaaa cacggtgaga agataaaaaa ccatcagcac caaagttaga ccatattaca
     7081 ttttgaccaa ttaatcttct atcaggaaac gcatgtaatg tttgaagagt attggaaata
     7141 acatctttaa taccaactaa atttgaagag ccacaatgca ttgtaacatt attgtgatat
     7201 gtatcataaa taacacctat acctttttct tcccagatat tatgtgtaat cttcataata
     7261 taatctacaa aatctctata cttagaatca aatccaggta tttcctgttc cctttttgtc
     7321 tgttttgaaa aatcattgta atccattact ccaacaggcg ttacttctaa tgaatctcca
     7381 tagtaaattt ttgtagatga catattatct tcccccttaa atataacttt tttatttttt
     7441 tcagtaagag tatttgtatt taatttatct gtatccactg tatctatgtt aactttattt
     7501 atgtcggatt tatttgtgtt tgttttatct atattccctt tatctatatt tcttttatat
     7561 gtgttcgttt tattctcatt tgtttgattt tcatttatat tactaaaatt agtttgattc
     7621 attttagctt tgttttcttt aaccgtacat gattcaagcc cacttgtaga aacttctttt
     7681 tcttactctt tacttgttgc attatttttg ttggtagatg ccactttata tccccctttg
     7741 ttttagaata cgtatgcata actaagcatt aaaaatactt ttagttctct caagaatatc
     7801 aagaccttgt tgtttcaacc aataaggaat atcaattaac acccagtttt cttgaagttt
     7861 atcgccctta cgataataaa catcaacaac ttgcatatct gctttaacct ctccacctgg
     7921 taatcctaaa aaacctccac atggtacatt agtcagatta ggccatccaa agaaacaagc
     7981 aaaattacct tctgcaaatc tacatacatg cccattgaaa gtctttcctt ttaaattatt
     8041 tctaaatggt agctggtgtt gctcttgata tctaggtata gtataagaag caccaattcc
     8101 acctggacca taccaaatca tatctttagc ccaagatttt tcaagtattt ctggtgggca
     8161 tcccatagca ccactttcat ttaattcaga taaatcatct accattttat ttactaatgc
     8221 taaagttttt actccttcaa cttcatctgc atcttcaaaa agtaatccat tatggtcaat
     8281 tggccctgga tatacaaaat atgaacctgt ttgtggtggc aatggattaa ctcctgcttg
     8341 aatcataaac ccaattatat ctacaaataa tccagtttta gcaattttac catcttgaac
     8401 acagttaaat tctgcatatc ttaaactaat cattttacga gtatgtttaa tgccaagcca
     8461 atcgttatca aaaagtccca taaaatgccc catactcatt acccattcac tattgtcaat
     8521 ctcatttgtt cctgcaatga aaatatcttg tcgtctttgc atattactca atgatttttt
     8581 taaaggcttc caaaatacat ctgctacatt ttcagtgcct tcttgttcac gaaatggata
     8641 cacacctttc cagttataat ctgatttcat atgttgcttt aagacatttt caacctcatc
     8701 cccagtagca ttttctaatg cttcaaaata atttcttaca actttttttg aatcctgata
     8761 ttttcccata agtatctcct cccagattta tttaagttat aaattaactt tctcatttta
     8821 tgcatacgat ttccttttta atgacttttt agctgtttta agtttatttt atgaatacat
     8881 atgcattttt ctaaatatta acatatatct aaaaaattgt aaagaaaatg ttatcataaa
     8941 aatttaattt ttgacttata tctatttaaa acaacagaaa aggtttaaaa cgtaatattc
     9001 tactgggtct accatacttg ctcataagct gttcactcac tacctcacaa taaccagaat
     9061 cacacaatct aagtataatc ctgtccatag ttctaatact tacaccacat atagtagcta
     9121 attcctttga tgtaaattca gtttttccac tatttattat tttattgaat actttatata
     9181 cagtattagc acttagccct gtctctgtag caatttgata aaaacgttca tcaaaactat
     9241 ttttctcttt gacagtagga tttggcttta gtggtcccat aatttctcca ttttcaaaaa
     9301 ctacatatgc tgcatcattt ttttgacttt gagccatctt aatactctca taagcgttaa
     9361 atttagcttc atttgctgtt tttccataac caattcctat ataagtgttt ataactgaaa
     9421 cttcacgaat catatccaac aaataaatat ctctgtattt ctttgtttct aactcaagta
     9481 tttttttagt tgtaaaaatc ataaattcac ttctactctg ctctaccaaa acaccatcta
     9541 tacggctatt gaaatggtat agtttatcaa gaatcttaat cctttgtgaa agataagcgt
     9601 actcatcttc cttcattagt gaatattctg aaggcatgtt cagtttaata gcaagaacaa
     9661 taatctgatt ctcattgttt ttctttgcaa tataacgcat ctgaatgttt tttatacttt
     9721 gcaccattac gtcctcagaa ggcaaggcta aaactactgg aatattatct tttttcatta
     9781 tatgataggc ctcttcaaga cctgtaatac aacaacatac atcattattt tgataattat
     9841 atttatgaaa ttcaagcaca aactttatat agtcctcttc taaatacttt tgctctgcaa
     9901 aaaacatatg ttcatcctta aattcaactc caatttcttt atacaatctc ttcatcatag
     9961 ccttatcata agtatctata ctaagtctac taatatcgaa tttaagcaaa tatgtaattt
    10021 caagcaacac tctgtacaat gttgtttcat gtctaggaat ataatcagac aatacaaaat
    10081 ctttttgtct tttttcaaaa aatttaaatg gcgacttacc tgtaaaaaga actgcatcca
    10141 ctctacctct atatttttcc aataaatcag gtacttcaat atatctatca tatctaagaa
    10201 aatctgcttc aatattagga aaattctttt tacttactgc tagtatttta tcgattacca
    10261 tacctggtcc tacataaagt attttcattt cgtctctcct ttcctaatga tactattatc
    10321 tcttaaaaca ttttctaaac ctaccatgac taaagccaca ggactcctga ttcatagaat
    10381 tttgaataat caattatacc taatataaaa agttacttta agttttttaa ttacgactat
    10441 ctgttgaaac atttttgtat ttaaattttt gtatttaaat cttattcatt aatattaatt
    10501 acattttaca attaatatat tgttttttct acttaaagtt aaattcttta gaaaacacaa
    10561 gtagagtaat ctttattaat ttaacaaaaa tagccttcct taatattcaa agaaagacta
    10621 tttttataaa agttcttaat gtattctatt ttgctatgct aagaggattt ttaattacac
    10681 gtccagcaca tacatcagtt tgctttcctc ctgccaatgc aattttacca ttcaccaaca
    10741 catattccac tcccactgta tactgtttag gattactata agtcgcttta tcttctattg
    10801 tatctgggtc aaataccaca atgtcagcaa aataattttc tttaagtaga cccctttctt
    10861 tataaatgcc taagcgtttt gctgaaagat aagttatctt tttaactgct tcctcaaaag
    10921 tcaacatacc tttttctcta acatagtaag agaaaattcg tccaaaagta ccaaatgcac
    10981 gaggatgagg ctttccaaga gaaagtaaac cttctgtaga aaggtccata ctatcagaac
    11041 ctatacatga ctttggatgg caaacaacct tatctgtatc ctcttgacct tgtgtatgaa
    11101 caactacttg aattttactt ttttcttcaa tcaaaagcct aaaaaacgta tcaaatggat
    11161 tttcaccatt gattttggct acctccatta aagttttacc ctctacatat ttatttgctt
    11221 cagtcattac agaggctagt acaacaccgt tccacccacc tgctaattgg tagaaacatt
    11281 gccatccagg aatcccttcc tccaactctt ttataattct gtctctattt tcttgtactt
    11341 ctaatcgttt taccatattt tctacaccgc cttcaaaagc ccaaggaggt aaaagtgcac
    11401 ccaaagatgt cattccagct gtatatgggt aacaatcaaa agttacttcc aaaccatctg
    11461 cctcagcttc atctagcttt ttaaatacct catcaatagt tccaaaattc ttatgaccca
    11521 taacttttaa atgagaaata tgtagaggaa ctcctgcagt cttagctata taaattgctt
    11581 catcaagagc ttccatttct tcatcacctt catctctaat atgagatata tagtatccat
    11641 tgtatggtat caattcctta cataattcag ccatttcttc tttctttgtg tatgctcctg
    11701 gtaaataaac taatcctgat gaaagagcta cacatccagc ttccatagct tttctaactt
    11761 ccaacttcat atttttaagt tgctctaaag tagctggttc ctttgaaaat cccatttcat
    11821 tgatacgtac aggtccttgt gctacataag ctacaacatt gactgctgga gaattttcag
    11881 ttaagtaatc aaagtattct tgcattgtat tccaatgaag ctctaatttt gttggaattg
    11941 taccaattat cctagttcca agataatcaa ttaactcttg cttcttctct tctcttatcg
    12001 gagcaactcc tataccacag tttgcaataa catctgttgt tacacctgta tggatacggc
    12061 ttcttgtgta tttatcatac acaagagata aatcagaatg agtatggaaa tctataaaac
    12121 caggtgatac aaattttcca gttgcgtcta tagtctcttt agcctctttt tgacttaaat
    12181 ctccaatagc catgattttg tctcctacaa tccctacatc acttttatat cttgaatttc
    12241 ctgtaccatc aacgattatt ccattgacaa ttttaacatc aaacatgctt tttctccttt
    12301 caagacttat ttatattcat atttcttaat aaacaatcct attctttttt ctcaacaaat
    12361 aattctagtc tttctcctta ataagcaatc ctattctttt gttttattgt tatcaattac
    12421 aaagaagacc cttgtgataa gtatcccacc taacacaata aacaatgtta ataatccacc
    12481 tggtatacca attttttcac caaagtacat aattgctaac gctacagcaa tcgtacatcc
    12541 accagctcga atatccttac gtgcaatatc aacataaatt gctccaaata atgctggaag
    12601 tatataatta aatgaattag taacaaattc aggtaacaaa ggaattactt tatagcctac
    12661 aatggtaaaa atggtaatca tagaagctga tacaaagatt gaacaacatg taccaattgt
    12721 tccaacaact tcaccctcat gagttcctgc ttctacacct gcaattttct gtgccattga
    12781 tgctgcaggc atacgtatat ctccaacaga acctgcaagc caacctatat aagaacctgg
    12841 agctcctagt gtaggataat aagctatagg ttgaacaatc caactaaccc cataagtcgc
    12901 agcgactaac ccccaaattt gaaatataac agaaagcatt ggcatctgac caaagcgaat
    12961 acctacatag atagcgggaa taaagtttgc aataattgca agacctatag aaattctccc
    13021 tatttttatc atctttttat catacataat tatcacctct tatccgtttt aatcacgata
    13081 atataatctg tgtaccaaac ataccaatta acatggcaat acctaaggat aattcttgta
    13141 atcgttgatt ctttttaaat aaagttgtca atactagcat aactatagct gaaataattg
    13201 ctggtgtaag ttttggtatt tcaaatgttt ttatttgatt tgaaagaagg taagcaaata
    13261 atccaactgt agctcctgca agtagttttt taacccaagt aggattatac ttcatgttca
    13321 tcttttcaac aattccacgc attctatgac ccaaaataaa tacaacaaat agccaaccta
    13381 agttatttaa agccatcccc catagtgcat acgaaaaagc ttctgctcca aatgcagcac
    13441 tacctacttc taccccagat aaattggatg taagagatat tactccaagc tctgttctag
    13501 ctgctccgac atcacagagc ctcatccaag tcgtaggagc gccaatcaca gctaccagtg
    13561 ataataatgt aataacagga gatagagaag gtccaatggc tgtaacacta gctgagcgaa
    13621 ttgctgcttt aattcctttc ttttcaatac caagatttga agcctctttt agtgcctctt
    13681 tcataaatac gattgcttga acaactgaaa taattactaa aaaactagaa acaatccaaa
    13741 gacctgggct attaatcatt tcttgaaact tcatacttta ttcctcctta aaataaattt
    13801 ttcagcattt tattgtgagc tttctttctg taatcttgtt atgtttttat attgttttaa
    13861 tttattttat ctaagatata gtatctttaa taggagatta tctgtcttaa agtctcacta
    13921 aaaacattaa tacttaaata ttttattcat aattagtaaa tatcagaaaa ttcacatatt
    13981 atttttttaa cctgtaatta actt
//
LOCUS       DAEPUT010000103        13994 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.106, whole genome shotgun sequence.
ACCESSION   DAEPUT010000103 DAEPUT010000000
VERSION     DAEPUT010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13994
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.106"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            287..1180
                     /locus_tag="KRL22_003318"
     CDS             287..1180
                     /locus_tag="KRL22_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HBH1273761.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1180..2574
                     /gene="gltA"
                     /locus_tag="KRL22_003319"
     CDS             1180..2574
                     /gene="gltA"
                     /locus_tag="KRL22_003319"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HBH1273762.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            2940..5159
                     /locus_tag="KRL22_003320"
     CDS             2940..5159
                     /locus_tag="KRL22_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1273763.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5306..6052
                     /locus_tag="KRL22_003321"
     CDS             5306..6052
                     /locus_tag="KRL22_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273764.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6052..7932
                     /locus_tag="KRL22_003322"
     CDS             6052..7932
                     /locus_tag="KRL22_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273765.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIILGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGAVCLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGILI
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKTNFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            8051..9442
                     /locus_tag="KRL22_003323"
     CDS             8051..9442
                     /locus_tag="KRL22_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1273766.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9549..10589
                     /locus_tag="KRL22_003324"
     CDS             9549..10589
                     /locus_tag="KRL22_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH1273767.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11078..11731
                     /locus_tag="KRL22_003325"
     CDS             11078..11731
                     /locus_tag="KRL22_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH1273768.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            11807..12016
                     /locus_tag="KRL22_003326"
     CDS             11807..12016
                     /locus_tag="KRL22_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273769.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12156..12722)
                     /locus_tag="KRL22_003327"
     CDS             complement(12156..12722)
                     /locus_tag="KRL22_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBH1273770.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDIIKK"
     gene            12883..13536
                     /locus_tag="KRL22_003328"
     CDS             12883..13536
                     /locus_tag="KRL22_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBH1273771.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13694..13870)
                     /locus_tag="KRL22_003329"
     CDS             complement(13694..13870)
                     /locus_tag="KRL22_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273772.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT         5474 a         1395 c         2361 g         4764 t
ORIGIN      
        1 ttacaaattt ggcataatat agtatacttt aagtgtgtat taggttaaat ctataacaaa
       61 ttagacgtat gatatagact tagtgtttat tggcatttac aagaaatttg ttaatatcaa
      121 ctatttgtag tttgggcagt tataattatt atagggggga tgtccaatac aaaacaatca
      181 accaagaact aatattatat tataaagagt tatagttttg tgtgtttatg tttttaatta
      241 aatttaaagt gggaaaaata tatttgttag aatggagaat agcgagatga gtaataaaat
      301 agttagtaag agacaattaa cagatagtat ttatttaatg gaaatagagg cacctagagt
      361 tgcaaaatct tctcaaccag gtcaatttat aataattaaa aatgatgaaa agggagagag
      421 gattcctctt acaatagctg actatgatag agaaaaagga acagtaacta ttgtattcca
      481 aacagttggt gcttcaacta aaaagttagc aatgtttgaa gaaaacgatt ttgtaatgga
      541 ttttgtaggg ccattaggac aagcaagtga atttatacat gaagatatag aagaattaag
      601 aaataaaaag atattatttg tagctggtgg agttggttct gctccagttt atccacaagt
      661 taaatggttt aaagagcatg gattagatgt agatgtaata attggtgcaa gaactaaaga
      721 attaattata ttagaagatg atatgaaaaa agtagctaaa aatgtatatg tatcaacaga
      781 tgatggtaca tatggattta atggaagagt tacagaccta ttaaaagatt tagttgataa
      841 tcaaggtaaa aaatacgacc aagcaatagt aattggacca atgataatga tgaaatttat
      901 gtgccaatta actaaagaac taaatatacc tactatagta agtttaaata caataatgat
      961 agatggaaca ggtatgtgtg gtggttgtag agttagtgtt ggaaatgaaa ctaagtttgc
     1021 atgtgtagat ggtcctgaat ttgatggtca tttagttgat tttgatcaag caatgagaag
     1081 acagtctatg tacaagactc aagagggaag agctatgcta aaacttgaag aaggcgatag
     1141 tcatcatcat agtaattgtg gatgtggagg taacaaataa tggatgctaa aaaagtaaaa
     1201 gtaccagtta gagaacaaga acctgctgtg agagcaacaa attttgatga agtatgctta
     1261 gggtataata aagaagaagc tatggcagaa gctaatagat gtttagcttg taaaaaacca
     1321 aaatgtgtgg gtggatgtcc agtaggaatc gacataccag ggtttataac aaaaattaaa
     1381 gaagatgata tagaaggtgc tgctaaagta atagctaaaa gcagttcatt accagctgtt
     1441 tgtggtagag tatgcccaca agaaagtcaa tgtgaaggtg tatgtatact tggaataaaa
     1501 tcagatgctg tatcaatagg taaattagaa agatttgtag cagattggtc aaaagaaaat
     1561 gacataaatt tatctgatac agagcctaag aaaaatcaaa aagtagcagt aataggaagt
     1621 ggtccagcag gtctagcttg tgctggtgat ttagctaaaa aaggctatga tgtaacaatc
     1681 tttgaagcaa tgcatgagcc aggtggagtt ttaacttacg gaatacctga gtttagactt
     1741 ccaaaacaag ctgttgttca acctgaaata gacaatataa gaaaattagg tgtaaaaata
     1801 gaaactaatg taattgttgg taaaacaatt acagtagatg aacttataga agatgaagga
     1861 tttgaagcta tattcatagg ttcaggagct ggtcttccaa tgtttatgaa tataccaggg
     1921 gaaaatgcaa atggagtatt ttctgcaaat gagtttttaa ctagagtaaa cttaatgaag
     1981 gcttatagag atgattatga tacacctatt agttctggta aaaaagttgc tgtagtaggt
     2041 ggtggaaatg ttgctatgga cgctgctaga actgcattaa gattaggttc agaatcatat
     2101 atagtttata gaagaagtga aaaagagctt ccagcaagag ctgaagaagt tcatcatgca
     2161 aaagaagaag gcattatatt taatacatta acaaatccta aggaaatttt agtagatgaa
     2221 aatggatatg ttaaaggtat ggtttgtata agaatggaat taggagagcc agatgattct
     2281 ggaagaagaa gacctataga aatagaaggt tctgaatttg tacttgatgt agacacagtt
     2341 ataatgtcac ttggaacaag cccaaatcca ctaatatctt ctacaacaaa gagtcttgat
     2401 ataaataaga agagatgctt aataacagat gaaaatggtc agacttctaa agagggtgta
     2461 tttgcaggtg gagatgctgt tactggagca gcaacggtaa tatctgcaat gggtgctggt
     2521 aaaacagcag cagcatcaat agatgaatat ttaaaagcaa aagttaatgc ttaatttgta
     2581 aattaaagag agggtgtctc aaaatgaact ttttagttca tgaggcactc tttttgtaca
     2641 aaatcaaata tgttttaatc atttcaacaa tgaaaatttc attcctgtag aaagtctaac
     2701 ttttaggtct tagtacaatc tctattttga tgtagccact tttttagatg gtttaataat
     2761 ttatcagtta ttattgtaat atttgatact aagtaacata actttgtcta actatgataa
     2821 aatagttata caataaaggt cttgtaagga gtgaataatg tgtggctaat aaaatcagat
     2881 ttgtcaaatc taacattaaa taatagaaaa ataaattgtg taattaatgg tattttaata
     2941 tgaaaaaaag agaaaaagta tttgatgggc tagtttttaa gcatatatta atcttattaa
     3001 tactattagt tttgattgat ttaacaagta ccatcatata tgcaagtaac tctatggaaa
     3061 ttacttctag aaatatgatt gaggcatcaa aaagagaact tgaaaactat ttagaagtaa
     3121 acatatcttt attaaaagct cttagtcaag atgatagatt ttctaatggt gaaacatcac
     3181 taattgaaaa gggaaaatta ttaagtccat atcaaaagga atataatctt tttatgattg
     3241 gtataacaga tacaaaagga aatgcttcaa gtacatatag ggaaaatgtt aactcaataa
     3301 aagataagcc tagttttgag aaagcaatta aaacaaagca agtagtagtt tcagatattg
     3361 aagtcagtaa tgtaacaggt gacaaagtat ttatcatata tgtaccaatt gtaaaaaata
     3421 atgagatgat tgggaccatt tttgcttctt tttattttca agatgtaaat aatttaataa
     3481 gtagaagcaa ttttgatgat tctattaaat ttctaatgat agataaagat tatactatta
     3541 tttctcatcc aaacaaaaaa tatgtaaatg ataaaagtaa gatgcttgat ttagaaggga
     3601 atattatagg aaccactaaa agtgaaatct taaaaaatat aaataaaaaa tgtcaaggtg
     3661 attttttatc ttgggataat tggagattat ataatgtaaa atatacgaac ataaagtgga
     3721 ctaattggac tttagtatca aaatgtaata tatttaagaa ctttaaaaat ctaatagtta
     3781 attttatgat aaagttgtat ttttatatag taatatttat gatattgtgg aaattaagta
     3841 atgctaaatt aatagaacaa cttaaaaaat tggcttatta tgattcttta agtggaataa
     3901 aaaataaaga aaagtttaga aaagattcta tgtatatttt aaagaattat tatcaagata
     3961 atttttactt agtacaattg gatgtcaata aatttaaata tataaatgag atgtttggat
     4021 atgctgaagg gaataagata ttaattcata tatcacaggt tttaaataat aatacaaata
     4081 aatatgaaat ttgtgctagg atggataatg accattttat attgttgatt gcttgtaaca
     4141 ctgaagatga acttttaaat agattatcta aaataaataa agaaatttgt aacttaaata
     4201 ctactaactc atctaagtat aaaattgtta tgtcaagtgg aatatataag attactaaaa
     4261 aggatgatat taaaaagatt gacttgttaa ttgatagagc aaatattgca gcaaaaagta
     4321 aaaaggaaaa atatgaacat tcatattcat tttttaatga agatacaaga aatcgattgt
     4381 acaaggaaaa acgattggaa gataatatga ataaagcttt agaaaaaggt gaatttatag
     4441 tatattatca acctaagtat agtttagatg atgtaaatga aattgaagga gcagaagcct
     4501 tgataagatg gaatagtcca gaatttgggt ttatttcacc tatagatttt gtacctttat
     4561 ttgaaaagaa tggttttatt gtaaatattg atatgttcgt gtttgaagaa gtatgcaaaa
     4621 cattaaacaa gtggataaat aaagggtata ctcctgtacc aatctctgta aatatgtcta
     4681 gagttcattt atatagggat aattttatag aaaatataac tgatttgata agtaaataca
     4741 atatatctcc tgagtttatt gagcttgaac taacagaaag tgttgtgttt gataatttaa
     4801 atatattgat tgatataatg aaaaagatta aagagatagg attccttata tcaatggatg
     4861 attttggttc gggatattca tctttaaatc tgttaaaaga cctttctttt gatattttaa
     4921 aattagatag aggattttta atcgaaacaa cagatacaaa acgtggaaaa attattattt
     4981 ctaagattgt ggaaatggca aaagcgattg atattaaagt aatctgtgag ggcgtagaaa
     5041 cttatgaaca agtagagttc ttgaaagaga taggttgtga taaggttcaa ggatacttat
     5101 ttgctaaacc tatggtatta gatgaatttg aaaagcactt aaactttaaa tttgattaat
     5161 cattaataat tattagacta taagataccc taacaactta cttacaaata tgtaagttaa
     5221 ttgttagggt atttttatgg ttaaagtagt atattcacga tattatggta ttgtagtaaa
     5281 aataaaaaat tatggagaat ataaaatgaa catattgagt attagaaata tatcaaaaac
     5341 atattgtgga aatattccat ttaaagcatt agataaggtt agtctaaata tagaaaaggg
     5401 agaatttgtg tctgttatgg gaccatctgg aagtggtaaa tctactcttt taaatataat
     5461 atctacagtt gatagacaga gtgaaggtga ggttgtatta gatggatatg atgtaagtaa
     5521 attgaaagga gaaaaacttg ctgaatttag aaggaaacaa cttggttttg tatttcagga
     5581 ttttaatttg attgacactt taactgttgg cgaaaatatt atgttgccac ttacactaga
     5641 gggggcaagt atcaaagata tgaatataca aactaaaagt atatctaaat ttttaggaat
     5701 agataaaatt ttagatagaa aaacctatga aatttcagga ggtcaagctc aaaggtgtgc
     5761 tattgctaga gctattataa ataaacctgc catacttctt gcagatgagc caactggaaa
     5821 tcttgattca aaatctactg atgatgtttt gaaattattt actaggataa acaaagaaca
     5881 aaaggtaaca acacttatgg taactcatga agcatatagt gcaagttatt cagatagagt
     5941 aatttttata aaagatggtt gtatatatac agaaataaaa aaatctgaaa gcagtaattc
     6001 tttctattct gatatactag ctgttttgtc tcaaatagga ggtgtaagat agtggatttt
     6061 agaaagtttg cttataataa tatagttaga aatttcaggg catatttagc atatttttta
     6121 agttctgttt tttctataat gatatttttt gtttttgcag tgtctatgtt ccatccaatt
     6181 ataacaaaat ctggaatgca gagtggttct actgcattta tggctcttat gacttcagaa
     6241 ttaataatat taggttttag tctacttttt atattgtact ctttaggaaa tttcttaaaa
     6301 tatagattga aagattttgg agtattgatg ataattggaa tgagtaacag acaactgaaa
     6361 aaattgatat taattgaaaa tttgataata ggatttttag cagtgatgtt aggaatatta
     6421 cttggtttat caatttcaaa attgttttta ttgtatttaa gcaaactgtt ttatatgaat
     6481 ttaactgaat tttattttcc agtaaaagca atgctattga ctattgtatc atttatgatt
     6541 ttatttttga taacaggacc aatgagctta aaattattga gtaaaaagag cattttagag
     6601 cttttagtag gtacaaaaaa gcctaaaaaa gagataaaat cttcaaagct atttggaata
     6661 attggtgcag tatgtcttat attaggatat gctatgatac tatttggcaa taagttaaaa
     6721 ataaatggag gtatgtatac aacagcacta ttaattactt tggggatatt tttatttttt
     6781 tctcaattta ctattttgat attaaagtat ttaaaaaata aagaaaaatt ttataagaac
     6841 aaagtaaata tgttacttat aagtaatttg atatataaat taaaggataa tacacgattg
     6901 ttatttttaa taacaatact tttatcggct actttagtag catttacaac aacttcaaca
     6961 cttgtaagtt ctcaaggaga agcttctaaa aataatttcc caatggttta ctcatatttt
     7021 tcagagcata ataatgaaaa agaatatgaa gaactacaac aaattagaga agcaatcaaa
     7081 ggatatgatt ataaggagtt aagttttcct gtacttaaat ataataggga agtcttacta
     7141 agtgtaaaga attataacaa attatcaaag gaattgggat tagataaaat tagttcaaag
     7201 ttagaaaaat atgaagggat tctaattcct agtagcaatt cacaagaaca tataaattct
     7261 ttaaaacaat taaaaaatta tagtataaaa aatttaaata tagaagtaaa aaaatcaaaa
     7321 aataaaataa tttttcctac aggactgttt agtaaagttg tggttataag tgatgactta
     7381 tacaatgaag taaaaggtga attttcaaaa actaattttc atggatttga ttataaaaac
     7441 tggcaaagca gtgcaaagat aactgaaaat ttaaaagaaa aacattttaa tttggataga
     7501 gaatataaca ggtcatattt tttaacatta ccagatatgt atttagtaga gttacaacaa
     7561 agtaaaattc ttcaatttat gggtgttttt ataggagtga tattatttat agcagttttt
     7621 agttttttat acttcagatt atatacagac gagatagaag ataatgtaaa gtacaaaaaa
     7681 ctatcaaaaa taggtctatc ttttaaaaat atgaataaga ttgttagtat agagataggt
     7741 acattgtttt ttataccgta ttttatagca attataaata gcataatttc tttactgttt
     7801 ttaaatcaag tattaaataa tagttttaag ttagaaaatt tgggtatatt actactgata
     7861 tcatctatat attcacttta tttttactta ttaaaaaaaa tttatactag aaaagtttgg
     7921 ttttttgatt aaagtggtat ataatagata tataaattaa tatttaaaaa gtagttaata
     7981 ttaggggagg gcatttgcac ctcccttgta atatgtggaa aattgaatat tagaaggagg
     8041 aggagacttg atggaaaatc aacaattatt aggaacagaa cgaattagta aattactact
     8101 aaaatattct ataccagcta taataggtat gttggtaaat agtttatata atgtagtaga
     8161 tagaattttt attggaaata taccaggggt tggaccactt gcaataacag gtcttggtgt
     8221 aacaatgcca ataatgacaa taatacttgc atttgggatg ttgataggta taggaactac
     8281 tactaccata tcaataaaac ttgggcaagg taaagtagaa gaggcaagaa aacttatagg
     8341 aaatgcaatg acgttatctg taataacagg aattatcata atgatacttg gaatattatt
     8401 tgcaaataaa atacttacat tgtttggagc aagtgaaaat actttaatat atgcaaaatc
     8461 atatatcaat attatattat taggtacagt agtaaatctt ctttcctttt ctttaaacca
     8521 ctcaataaga gctgatggta gtcctaaaat ttcagcagga ataatgatag taggatgttt
     8581 aactaatata gttttagact ggatattaat atttggattc aatttgggaa tacaaggagc
     8641 tgcaattgct acagtaactt ctcaggctct tacagctatt ttaactatag ggtattatat
     8701 aagtggaaaa tcaaacttac gattcagtaa atctaatcta aaattagata aaaagctaat
     8761 aaaagcagtg tttgcaatag gtatgtcgcc atttgctatg caacttgcag caagtttagt
     8821 tcaagtaata tcaaatattg cacttaaaac tcatggtgga gatttagcta taggggctat
     8881 ggctactatt tcttctattg caatggtatt tttgatgcct atctttggaa taaatcaagg
     8941 agcgcaacct attataggtt tcaattatgg agctgaaaaa tatgataggg ttaaaaaagc
     9001 atatttaggt tcattagtag tagctactat aattttatgt atgggtatgg tagtagttat
     9061 gcttttccca gaagctatta taggtatatt taataaagac cctgaactta tgaatatatc
     9121 tgttaatgga ttaagaatat acttacttat gttgccaatt gtaggcttat cagttacagg
     9181 aacaaacttt atacaatcta taggaaaagc aaaaatggct atgttattga gccttttaag
     9241 acaagtaatt ttattgatac cagcagtatt aattcttcct acattcttag gcttacaggg
     9301 tgtatggaca gctcaaccag tgtctgattt tatagctaca gtaattacag gtatagttgt
     9361 atttagagaa ttaaaaagat atactcctaa aactgaaaaa ttaaatgaaa atgaaagact
     9421 aaacgagata actactgagt aaaaatataa attcagataa ttgagcaaga aattgcaaaa
     9481 aatacgatta tatgataaaa taaaaccgct gtcaaggata agagaaattc taattatgga
     9541 gtgattttat ggaatttaca aagaaaagca aattaaaaaa tatgtatgta aacatgaatg
     9601 tagctagaat gttgtctaag ataaatgagt ataagggtag acaactgctt tacaaaaaac
     9661 aaccaaaaga aattttagaa aacttagaaa aaaaatcttt agtagattgt tctgaatcta
     9721 catacattgg aaatcaaaga gatagtagta attttaatct agaaaagttg ataagtaatg
     9781 aagttacacc tagaagtaga gaggaattga gtattgttga atacagagat gtggtaaaaa
     9841 ctattaacag tgcttatgag agtattccca tcagttcaca aacgattctt gagcttcatg
     9901 gatacttata taaattttca tctactagag gaggaagtta taagtcagat aatgatttta
     9961 ttgaacacaa tttaaaacct agcgaattta taagtactga ttcaagtgtc aataaagttg
    10021 aaaaagctgt agaagaaata tgtgaagctt ataatacatt gatagaggaa gatgaaattg
    10081 atatattaat attaatttct gcatttgtgt tagatttcat attgatacat ccattcaaag
    10141 aaggtaatat aaaaatggcg agagtactta ttctattgtt actaaataaa aatgggtatg
    10201 aagttggaag atatataagt ttaggaaaga tatttgatga tagttcatat gaatattata
    10261 gtaatttaaa ttatttgaaa gcctcaatag gtagtgaaaa agcagatatg aatgcatgga
    10321 ttgagtattt tttagagacg atattaactg catatgagaa gctggatgat agtttaaata
    10381 tatctgataa gaaaagacaa acaaaaacta gtagaataga gaaaataata aattctaccc
    10441 ttggatattt tacaaaagaa gatataagag atttatgtcc tgacattcca gaacctacta
    10501 taaatagagt ttttaataat ctaagaaaac aagataagat agaagttgtt gcaagaggaa
    10561 gaagtgcaaa atggaagaaa aaatattaaa aaatgtttag ataactaaaa tggtatagtg
    10621 ttttacacta taccattttt aatgtcatta gcatgagcaa taatttaaca acttaagcaa
    10681 tatcaatttt atttattgat tatttttgaa ctgaaaaatg gcgttatatg gtatacctca
    10741 gtggtaatta attttggatg agaagatata atattacaga atatattagg agtatatgta
    10801 gaaaaaatat aataaaagtg tgaggcttag taattaacaa attatgtggc ttcacacttt
    10861 tttataaaat aaagatactt agcagaataa tattttagtt aatatattta taagatggta
    10921 cttgtttggg taaaagtata aatagtaaaa aagtagaagt aatgtgtata aaaacataag
    10981 ttacattctg taataatagt tattttataa ttcaacaaaa gaatagaatg ggtatatttg
    11041 tgaaataata atataaaata atcttaggag tgagcttatg aagaaaaaat tattatatat
    11101 aaatgtaaat tcaaaacctg aagacttatc ttcaagtaaa actgtagcaa gaaaatttat
    11161 aaataaattt atggaaaaaa ataaagattt tgaggttgaa gagatagacc tttataaaga
    11221 acatatacca agacttgagt atcagtactt tgaaaaaaga aatagcatag ttagtgaaga
    11281 aaatgctaaa aatttagacg ataaggatag aaaagagctt acaaagatta gaaatctttg
    11341 tgaccaattt gtgagtgcaa gtgtatatgt aatagcagca cctatgtgga gtttatcttt
    11401 tccagcacca cttaaagagt atatagactg tataattcaa gatggaaaaa ctatatcttt
    11461 tgaaggcaat gataaaccac aaggaatttt aaatgatatt gatagaagta tggtatatat
    11521 acaatcttct ggtggacaca taccatgggt gttgaagcca gttatgaata aagggttaaa
    11581 ttatgtggaa agtattatga aatttatagg aattaaaaaa tttgatgaat tgttagtaga
    11641 tggaactgga actagtgaag aagaaagaca agctgcaata gaaaaagcat ctgaaaaaat
    11701 agatggtata atagatggga tgaaatttta attataatat tttattaaaa atataaagga
    11761 aaaacctctt ttaatgtaga aacttatatt gaaggaggcg agaatcatgc gagaagaaaa
    11821 aagtaatgaa aagtatgatt gttattggtg taatcaagag aataatttct gtgtagaaat
    11881 aaaagataat atagtcatga tagatgatgg cactggtacg ttaaaacaag ccgttttcat
    11941 agggtataaa caaatccaaa ttaatttaaa ctgttcacat tgtcaaaact taaatagaat
    12001 aaaattaaat ttgtagaatt ttaaaatgga aattattgaa ggaattaaaa atagaaagtg
    12061 ttaatattta gactgaaaat tatattttat acaataaaag tttatttaaa taacattgta
    12121 ttttaatatt tattttcagt cttactttat taaaattatt ttttgattat gtctggaaaa
    12181 tatctgtcta ctaatttttc tgaaatattt tttaattggt cagccattga agtcagactt
    12241 aataaggcta tcaataaatc atctttattt tctggattta tactaatatt ttcaaaatta
    12301 gactctataa agtccggtat attctttctt tgattttctt ttattaacat gaatttttcg
    12361 taacatgaaa ctaaatcttt ttcactgaaa ttatcctttt catacacacc atgtaagatt
    12421 cttttaattt cttgtattgt aagtgtattt ttcatagaat aaataattat catctgtaaa
    12481 atttgttctt tagtatactt ttttccctta actggtttga ttaatccctc tttgctgtaa
    12541 ttatttatca tggttttagt aagaatttta tcactttcaa atcttttatt agcagaaagc
    12601 ttattgtcaa ttagagaaat aatttgatcc atatataagt caatagatgg aatatcgttt
    12661 gaagttatat ctgcattatt tagtgtttct agtattatag tattaagttc attattcatc
    12721 atatgttacc tccataatat atataataca ctaaattaga aagtaaaaca atattaaggc
    12781 ttgtaaaaaa aacataaagt ggtataatta aatatataat atagtaatca aaactatatt
    12841 tatgaatctg atttttaaaa tacataattg taggaggacg aaatgtatca atttttttta
    12901 aagggtagag acccaataag cagtttaact cattttatag gtgcttgttt atctctttta
    12961 gcaactataa ttttagtttt tcaatctgtt acattacagg aaacttctct cttgatgata
    13021 gtatctgtat cggtatttgg actttcacta attgctttat atagtgcaag ttcgtattat
    13081 cattttttaa aggggacacc agaacaagaa ttgtttttta gaaaagtaga ccatgcaatg
    13141 atttacgtat tgattgctgg ctcttataca ccaatatgtc tgaattttat ggaaaaaaaa
    13201 gaaggcataa tatttgttac agcaatatgg atagttgcat ttattggtat aataataaaa
    13261 atattttgga tggatgcacc tagatggtta tctaccagta tatatttact tatgggatgg
    13321 gcaattgttt ttgatataaa tgcattcaat tcaattccta aggattgcct tagactatta
    13381 attatggaag gtgtatctta ctctataggt gcaattattt atataattaa aaagcctaat
    13441 ataagtcctg agtttggatt tcatgaaata ttccatattt ttattatgat aggttcttta
    13501 tttcactttt tagcagtttt attgtatgtt ttatagtttt aaaagatttg attaattgat
    13561 actaaaattc tacaatgaat aaaatggaac tgccttatat agattatatc ttcgacaata
    13621 agacagttcc ttattataaa tattaaattc tacttataat aaaattttga taaaaatagt
    13681 ccattcaaaa tgcttattcc ataattcctt taatgtactt ttcatttacg acatatagtt
    13741 tgaatttatg tactataatt atatcctcta aattctctga aacactaaca attctgacac
    13801 atttgtttct aatttctaca ggtaaatcta aatcatttgt taaattcaca tagtcatcat
    13861 atttatacat aaaatcatcc ctttacatta agatatactt attatactat attttaataa
    13921 gtttttttaa attattacaa tttttcccga aatttcattt tttatacata aaatttccaa
    13981 attaggtaaa gatt
//
LOCUS       DAEPUT010000104        13410 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.107, whole genome shotgun sequence.
ACCESSION   DAEPUT010000104 DAEPUT010000000
VERSION     DAEPUT010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13410
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.107"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            183..2042
                     /locus_tag="KRL22_003330"
     CDS             183..2042
                     /locus_tag="KRL22_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1273773.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVGRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2316..2915)
                     /locus_tag="KRL22_003331"
     CDS             complement(2316..2915)
                     /locus_tag="KRL22_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1273774.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3018..3815)
                     /locus_tag="KRL22_003332"
     CDS             complement(3018..3815)
                     /locus_tag="KRL22_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1273775.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3928..4033)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4125..5111)
                     /locus_tag="KRL22_003333"
     CDS             complement(4125..5111)
                     /locus_tag="KRL22_003333"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH1273776.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYISKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5595..7325
                     /locus_tag="KRL22_003334"
     CDS             5595..7325
                     /locus_tag="KRL22_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBH1273777.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7435..7515
                     /locus_tag="KRL22_003335"
     tRNA            7435..7515
                     /locus_tag="KRL22_003335"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7469..7471,aa:Leu,seq:tag)
     gene            7850..8365
                     /locus_tag="KRL22_003336"
     CDS             7850..8365
                     /locus_tag="KRL22_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HBH1273778.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKI
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8857..8961
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9171..11645
                     /gene="gcvPA"
                     /locus_tag="KRL22_003337"
     CDS             9171..11645
                     /gene="gcvPA"
                     /locus_tag="KRL22_003337"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HBH1273779.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISTLKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSIIVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11645..13102
                     /gene="gcvPB"
                     /locus_tag="KRL22_003338"
     CDS             11645..13102
                     /gene="gcvPB"
                     /locus_tag="KRL22_003338"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HBH1273780.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         5036 a         1590 c         2201 g         4583 t
ORIGIN      
        1 acttatatat tagaaaaaaa tttttgtata tatagaggac tctaaagatg aactatgtaa
       61 aacaaggttt atatattcta attgtataga aaatttattg taaacacatg tatattatta
      121 gaaaaaatag tttgaaggta ttcaataaac ataaaaaaca atatagggga taaaggtgtt
      181 ttatgaagag atttttgagg agaattatct tagttttatt tattttgttg atttttataa
      241 gttttatttc tattaaatta attcataatg ttggagatta tggaaaattg attaattatg
      301 ttgggattgt tcgtggagct agccaacgtc taactaaact agagatgaat catcaaccaa
      361 atgatgaatt aatagaatat attgatgaaa tcctacagga gttgattaca gggcatggag
      421 attatggttt agtaatcact gattgtaatg aatacaatga ggacttactt ttattagaaa
      481 aaaagtggga agatttaaat attgaaatta aaaaagtaag aatgaaagaa cagaataacc
      541 agttattaag tataagtgaa gagttttttt ctcttgcaaa tgatacagtg tttaaaatag
      601 aaaacttttc taaagaaaaa agtaattact taatgacttt aataataatt atatctatta
      661 taggtatatt agcatgtatc atattgattt tacaatatag taaaaaaatg gttagactgg
      721 aaaaattaaa tgtagattta aaaaatattg catataaaga tgaactaaca ggagtaaata
      781 ctatagaaaa atttaaattg gatgcaaatc aaaatatttg tatacataag gataagaaat
      841 ttgctgtatt ctatattgat tttgaaaact ttaaatacat taatgatata tttggatatg
      901 attatggtga catgatactg aaaagatatg ctaatcttat gatgaatgac atagggaaat
      961 atgaaatatt tgcaagagaa attgcagata gatttgttgc gttaagatgc tatgtagata
     1021 aggaagattt agtgggaaga caacgagatg tagacaatga actaattaat ataacaaatg
     1081 aaattaaaaa taaacatagt attactgttg ttagtggaat ttgttgtatt gaagatgtaa
     1141 atgaaaaatt aagtatagat ggtttaataa atagagcaaa ttttgcacaa aaaactgtta
     1201 agaataaacc aggtactaat tatgcttttt ataatgacag tattcgtaaa aaaatgattg
     1261 aagaaaatac tatcaagagt agaatacatg aagctattga aaaaagagaa tttatagttt
     1321 atttacagcc taaagttaat ttacatagtc aaaaaataaa ttgtgcagaa gctttagttc
     1381 gttggcttac tccggataaa ggtattatat cgccagcaat atttattcca gtacttgaga
     1441 agaatttttt tattgcctta gtagataagt atgtttttga ggaggtttgt aaatggatta
     1501 gaaagaggtt agatgaaaat aaaccttttg ttcagatatc agttaatgtt tcaagaatac
     1561 aattttataa cactaaattt gtagaaactt attccaatat acaaaataaa tacaggatac
     1621 ctaaaaatac tatagaaatt gaatttacag agagtgttgc ttttgagaat caaaaacatc
     1681 ttttggaaat tatacatgat ttgcatgaaa atggatttac ttgttcttta gatgattttg
     1741 gaaaaggtta ttcgtcttta agtgttttaa aagatttacc atttgatgtt ttaaagcttg
     1801 attctatgtt tttcaaggct agtttagata aagataaaga gaaaatagta ataaaaaata
     1861 ttgtacatat gttaaaagaa cttaatatca caactgttgc tgagggcatt gaatgcaagg
     1921 aacaagttga atttcttagg gatattgggt gtgatttagt tcagggattt gtattttata
     1981 aaccaatgcc aatattagaa tttgaaaaaa tattggataa agagtttgtt tataatagct
     2041 aaaatgtact ttataaaata tgaactaatt aagtaaaatt attttgtact gaataaattt
     2101 ttactttatt tacagaaaat cgcgaaaagt gtattccttt aagtgtggga tggatagcac
     2161 aaatagagga gaaaaaatat tggccatata agaatgcata ataatataaa tatttgaaag
     2221 gtcagcatca tataaaaatt aaaaagaaaa taaataattt ttctataaaa aagagactat
     2281 gagaaaattt actcatagtc tcctaaataa tgtatttatt ttcttcctgc aacccatttt
     2341 aatccccaat gaaattcagt atccatttct ctatgacctt tgaagtattt aactactttt
     2401 tcaacactga atgtctcatc atttacattt tctatcaatg ctattgaaca catattatag
     2461 ccatttttat gttcatcaag tttgacaact aagtctgaat cttgtttttg tttgattgtt
     2521 acaattccat cagcttcaga ccagttagct acaccttcgt atataaaagc ataaataagt
     2581 attcttttta tatcttttat tttattacca tttattctta aattttctcc ttgtgtatta
     2641 cttcctgttc tgtcatctcc atctaattga gcaaaaggtg gattgtctaa actaccaaag
     2701 gcatttccta atgcttgaac agcacctttt acaccatttt tcatctcaaa taggcaaccc
     2761 aaatctaaat ctatattact gcttcttaaa gagccaaaaa aacccttttt ttgtactttt
     2821 tgattccaat ttaaattaac taagatttca cctaaatcgc tattttcctt ttttgtaagg
     2881 tttatttttt gtcccttttt taattctata gccatagtaa tcttcctcca caaacataga
     2941 tttatttaaa tggtagcact taataagtca atattcaaca agattagaat aataatatta
     3001 aaattatact aaatatacta aaaagtagga atcacaatac ctttgtattt ttcttcaatt
     3061 aagcttcttg ctttatctga tgtaagaaca tcttgtagaa ctttaatctt ttcactgtct
     3121 ttatcttcag ttctaaatgc taaaagattt gcatactcgt catttatagg agctgtataa
     3181 attccgtttt tcttggcatc aagaccagca ggtacagcat aagtagtatc tataaatgca
     3241 gcagtcacat ctggaagaga agatggaatt tgagcaatat ctaactcttt gaattgtatt
     3301 ccctttggat tttctattat gtccttagga ctaactaatc catccccttt aggtaacgtt
     3361 aaaagtccaa tactttcaag gtatctaagg ttcttagaac aagaagatgg gttattgctt
     3421 attgcaattg tatctccttt tttaaattca tcaacagatt ttatcttata agagtaaagt
     3481 attgctgggc atacatatag ttttttacca gccattattt tgtaaccttt ggccttaaca
     3541 gcttctttta gataaggttc atgttgaaat agatttgcat caatttcacc attatttaaa
     3601 gcttcgtttg gaagtatgta atcatcaaag tttttaactt ctaaagtata tcctttttct
     3661 ttaataagtg gttttaattc ttctaataac tctcctcctg gaactaaagt agcaccaaca
     3721 acaatttttt tatcatcttt agctttagaa catccaacca cagctaaagt taatactaga
     3781 cataataaca aacataataa ttttttgaat ttcatataaa ttccctcctg aatataattg
     3841 attagttaaa aataaaatac cattctttat cacactgcaa aataaaaata agcctgagtt
     3901 taaactcagg ctttaaaagc taatttagac tcatctttca gtataatact gcaggattta
     3961 gcaccaatgt atataaaaat atactggttg ctgggtttca tagggccagt cccttcacca
     4021 ctctggataa gaagtatcaa tttttaatta tgttataaat attatcatga ttttttacgt
     4081 ctgtaaacat aattttataa atattttaaa atctttaatg tattttattt aacacctaaa
     4141 attccagaaa ctagaatatc agtatcagca cctaagaaat agtcatttat ttcaatagaa
     4201 tccagagtat ttctcaaagc attttcttca tgccttatac caataagttt attttctaca
     4261 aatgcaacat cacattttcc aaaaaaatct ccaaaaaatt ttatactagt tattatgcct
     4321 ttatcaacat ttaaattaaa ctcaacattt ccaccagaat attttaattc atttgaaaga
     4381 gtatattttg gtgaattacc aaaattccaa tcccaagttt cgtattttga tttagtaagc
     4441 ttttctattt gttttatatc atgctcactc aaacaataat tagtattatc agtatttgtt
     4501 ttagaaatat aatccattat agcatcttta aattctaata tatccatttt tgaatgtaaa
     4561 tgttcactta tattggttac acgagatttt acagatttta ttccttttcc ttcaaatttt
     4621 ataggtttaa cctttaatgc ttttgagagg tcatttattt cagatgaaaa taaaagagtc
     4681 ccatgatgca ttactttgtt tttgtagttg tattgagcat ttccagaaaa tttcttgcca
     4741 tctataagaa ggtcatttct tccagaaaat tcggcattga catctagtgt tttaagtaaa
     4801 tctattatgg gctgagtgaa tcttctgaaa tcactaaaat tattattgtt acaagctata
     4861 aatgtaaaat ttatatttcc caaatcatga aatacagctc caccaccaga ctgtctccta
     4921 acgacaggta tagaatattc ttttatatat tctaaattta tttcagaaag tgtgttttgg
     4981 ttttttccaa caattataga aggttcattc ctccataaaa taaataagtc ttcatcaaaa
     5041 ttttttagaa gatattcttc cattgctaaa ttaaaataag ggtttgtttt ttcattataa
     5101 attaataaca ttaaagtagt tcctccatag aattgataaa atttttatta tgaatacaat
     5161 taattttata attcgacaat aatataaaaa ctcctttaaa ttagaaattt taaaaactac
     5221 cttgcaaagt ttaaataaat aatatatact caaaatatgt ttaataaaag tgaatagaag
     5281 ggtagaggcg caataatcta tcagtactaa taaggagtta agcacagaga gttattagga
     5341 aaggagatat tgccgaagtt ttataatcga tgctttaaga ttatattgct gggggtacat
     5401 agaaaatatg tacaactgtc acaggtttat ttgtggtgag ctatcattta aggaattata
     5461 ttatatttat ttttactatt gttgatatat tgtaatgttt aagccttgag tgtttaccac
     5521 tcaaggcttt tttagtttta ttgtaacata ataccctgta cagttcacaa aattaaaagg
     5581 agagggagat ttatatgagg aacaaaaaaa ttaatattat ttttctgacg acaatcatgt
     5641 tcataatgtc aacagtaatg gtttttgcag aagaagatat agacactatt gcactagcca
     5701 atgcagaaaa atttgggatt ttaactttaa taccaccatt agttgctata atacttgcat
     5761 ttataactaa aaacgtaata atttctttac ttataggtat tctttctggt agttttataa
     5821 ttaaagctag tggtattaat gtttttgcga catttataca ggcattttta gatttagtag
     5881 atagagcttt agtatcttta gcagaccctt ggaatgcagg gataatacta caggttttgg
     5941 caattggagg agtaataaat cttgttgcta aaatgggagg agctaaagcc atagctgaag
     6001 cacttgctaa aagagcaaag tcagcaaaag ggacacagct tataacatgg tttttggggc
     6061 ttttagtatt ctttgatgat tatgccaatt cactaatagt aggtcctatg atgagacctg
     6121 ttgcagataa aatgaaaata tcgagagaaa agctggcatt tataatagat gccacagcag
     6181 caccagttgc tggtttagct ataatatcta catggatagg tcttgaggtt ggtttaatac
     6241 atgatgcttt tgaaagtata agtatagatg tagatgcatt tggtatattt ttaaatacaa
     6301 taccatttag attttacaat atattaatat tagctttcat tgtaatatca gcattattat
     6361 taaaagaatt tggtccaatg agaaaagctg agataaaatc tagaagtaga aaaattagta
     6421 tagaccttga tgaaggcgta gaagagttgg atgatttagc tccaaaaaat ggagtaaaat
     6481 tgagtgtatg gaatgctata atcccaatag gaacattgat aatagttgca ttagcatcat
     6541 tttattatag tggatataca tctataatgg gaggagacga taaggctctg atacaactat
     6601 ttacaaattc tccatattct tttgaagcaa taaaagaagc atttagcgca tctgatgcat
     6661 ctagagcatt attccagtct gcacttgttg caagtttagt tgctattata atggctgtag
     6721 taaaaaagat ttttacaata tcagaagcaa ttgatgtttg gatagatgga atgaaaagtt
     6781 tagtaatcac tggtgtaata ttaatacttg catggtcatt aagttcagta ataaaagagt
     6841 taggtacagc taaattttta atacacctat tatcaggttc actaccacca ttcttattac
     6901 caagtttaat atttggttta ggagcaataa tatcttttgc tactggaaca gcttatggaa
     6961 caatgggtat acttatgcca cttgcaattc cattagcata ctcattaaat cctgatatgt
     7021 cttatgtaat agtaagtact agtgcagttt taacaggtgc aatatttgga gaccattgtt
     7081 ctccaatttc agatacaaca atactttctt caatgggagc tggctgtaat catatagacc
     7141 atgttaacac tcaaatgcca tatgctatat ttacagcagt aatcactatt gtatttgggt
     7201 atataccagc tggacttgga ttgccaatat atatagtatt accagtggca atagctgcta
     7261 tatttgtagg tattcaaata attggtaaga aagttgatga agcggaaata gaacttgtag
     7321 aataaagata taaataagtt tcacctttta ttatcactat tttgttagtt tttagataat
     7381 tttaaaaagt tattgaaaat aatggcgaaa tatagtaaaa taaaagagtg ataagcggat
     7441 gtggcggaat tggcagacgc actagactta ggatctagcg ccattggcgt gggggttcga
     7501 ctcccttcat ccgcacttta cagtacttaa ttgtactgaa aaaaactggg gttgctggct
     7561 ttcggagtgg gctatcccgt ttttattttt ttgtatatat aatagattgg cactttagta
     7621 taaggtgctt tttttatagg caaaaacagt acatttattt ctgttttatt atcattcatc
     7681 tattagaata tactttagtt aagaatgtgt taataagtag tgttcacatt cttgataaaa
     7741 tgtggaataa tatgtatttt tactaagatg gaaatgaaat aattaaacca ttaaataata
     7801 ttataagatg atgaataagt agataaatca aattttgtag gaggatatta tggaaaaata
     7861 tatatggttg tttccattac tttttatttt tcatgatatg gaagagataa taggttttgg
     7921 aatatggctt aaaaaaaata aatcaatgct tgataagaag tatccattta tcagtaaaat
     7981 ttatgaaaat tatagtaccg aaggcatggc atttgctgtg tttgaagaat ttattttatg
     8041 cattattttc tgtatactta cagttataac agagaatcag tatgtatatc tactatggtt
     8101 aggtagtttt atagcatata ccttacattt ggtaattcat atagggcagt caatcataat
     8161 aagaaaatat ataccttcac ttattaccag tatcatatgc ttaccaataa gcatttggtg
     8221 tataagtaag agtatttata tagttgattg tgaaatgagt acaacaattc tgtacagtat
     8281 aattggcatt ataattgtag cattgaattt aaagtttgca cagtcgctga ttggaaaatt
     8341 tacaaagtgg atgtcaaaca tataaatttt agtttattgg acagttcaag gaatcagaaa
     8401 ttggaatttt atagtattaa tattttatag tattaatata atgtataaaa ttttatagca
     8461 atgtatttca taagtataaa gtgactagaa ttttaagaaa tatacaaatt ctataaaaac
     8521 taaataattt caagtatatt ttaaaaatct tatttttcac aagtttaaaa ttgtaaacga
     8581 tttcatcaag tctatgaata tacttttaac atgttatagt aaatctcaat ataaatttac
     8641 atttggttct ttgtgtgtta ttttaataat aaattaagtg aaaatgttat tttacattaa
     8701 tatataatat ctttgcataa gagtgaataa cataaaagag aaataattga taataaaaac
     8761 ttaacaaaaa aattaataca taaaaaaaaa taaatataat gtgttgacat ttaattgaaa
     8821 tattcataca ataaaattga aaataaatat ttccaaatga gattagcgag agagtccttt
     8881 atacgaaaag gcgccgaaga agaaatttaa gaaatgccaa tttttagaga agctttcagg
     8941 caaaaatatc gctaattgat gggactctgg agagacttaa gttaagatac tataagtcac
     9001 cgaagaagca aaataatatt aaattattaa atctttcagg tatacaaaca gggatatata
     9061 ggctaggatt attttccatg ctgatatatc ttttttttat gaaaaagtac aggaaataat
     9121 atcaaagtta cttaaataca gtaggtctaa ttttctaggg agggttatat atgaatgaat
     9181 tgaaaagagt atctttgtac aatatacaca aagagcttgg agcaaaactt gttgaatttg
     9241 ctggttggga aatgccttta gaatatgagg gtataaataa agagcatgag aaggtcagaa
     9301 aaagtgcagg tatatttgat gtatctcata tgggagaggt acagataaag ggagcagagt
     9361 cagaaaaatt tatacaaaac ctagttacaa atgatataag cacattaaag ataaatgaca
     9421 ttatatatac acctatgtgt tatgaaaatg gtggagtagt tgatgattta ttaatatata
     9481 aatttggtga agaagattat ttattagtaa taaatgcagg taatatagat aaagatgtag
     9541 catggataat aaaacaaagt gaaggataca atgtagatat aaaaaatata tctagtgaag
     9601 tgagtcaatt agcaattcaa ggacctaaag cagaagaaat tcttcaaaaa atcacagata
     9661 tagacttaaa ctcaataaaa ttttataagt caattccatc aataatagta tgtggttgtc
     9721 cttgtttagt ttcaagaaca ggatatactg gggaagatgg gtttgagata tactgtaaaa
     9781 ataaatatgt agaaataatt tggaatgaag ttctaaaggt tggaggagaa gatatatgtc
     9841 ctgctggtct aggttgtagg gatactttga gatttgaagc agctctacct ctatatggac
     9901 atgaaataaa tgaacacata tctccaattg aaggtggctt atctatcttt gtgaaaacaa
     9961 ataaagaatc atttattggc aaatcaattt tatcaaaaga aaaagaaagt ggagctaaaa
    10021 gaaagttagt aggatttgaa atgcaaggta aaggaatgcc tagaaatgga tatgatataa
    10081 ggattggtga taaaacagtt ggatttgtaa caacaggatg tgcatctcca acgacaggaa
    10141 aaattttagg tatgggaatt atagattctg aatatgcaaa agtaggaaat gaaataggta
    10201 tagcaatcag aaaaaaagtt gttcctgctg tgatagttaa gaaacctttt tataaaaaac
    10261 aatataaaaa agataatatt atattaaaca aagaaaataa attttcatat atacctgcta
    10321 caagtgaaga taaatcaaaa atgttaaaag tagttggatt aaattcggtt gatgaattat
    10381 tttcagatat accagaagaa gtaaaattaa aaagagattt aaatttggaa attggaaaat
    10441 ctgaattaga ggtaagcaaa atagtaaaaa gattgtcaga agaaaattta agtttagaag
    10501 acttgacttg ttttcttggt gctggtgcat atgaccatta tataccatca attataaaac
    10561 atataacttc aagatctgaa ttttatacag catatactcc atatcaagct gaaataagtc
    10621 agggaacttt acaagtagtt tttgaatttc aatctatgat tgcagaaatt acaggtatgg
    10681 aaattgcaaa tgcatcaatg tatgatggag caactgctgc aatagaagca tgtataatgg
    10741 caatgaatca gactagaaaa agtaaaatag tagtgtcaaa aactattcat cctgaaactt
    10801 tgtcagtatt aagaacttac ttacaatata aagattgtga gatagtagaa attgactttt
    10861 gtaatgaata tgggactaca gatatagaaa aattaaaagc ttctgtagac aaagatacag
    10921 catgtgttct tatacaaact cctaatttct ttggaattat tgaagaaatg gaagaaatag
    10981 aaaagataac tcatgaaaat aaggctatgt taattatgag tgtagaccca atatcattag
    11041 gagttttaaa aacaccaggt gagataggtg cagatattgt tgttggagaa gctcaatcac
    11101 ttggaaaccc tcttaatttt ggaggtcctt atgtaggatt tttagctagc aaatctaaat
    11161 atactagaaa aatgccagga agaatagttg ggcaaagttt agatgtagaa ggtaaaattg
    11221 catatgtatt aactttacaa actagagaac agcatgtaag aagagaaaaa gcaacttcta
    11281 atatatgttc aaatcaagct ttaaatgctc ttgtagcttc aatatatatg gctactatgg
    11341 gtaaagaagg atttaaagag gttggtatgc agtctatgaa aaaagcacat tatacttaca
    11401 ataagcttgt acaaactgga aaatataagc caatatttaa aggtaagttt ttcaaagaat
    11461 ttgctgtaca aggaaatctt aatatagaaa ctataaatga taaactctta gaagaaaata
    11521 tattaggagg ttataattta gaatacaatt atccagaatt aaaaaattca actttgcttt
    11581 gtgtgactga gaaaagaagc aaagaggaaa tagataagtt agttggaata atggagggat
    11641 tataatgaaa gaatacaata gtttgttgat agatatatct aaaaaaggta ggaaagcata
    11701 ctcacttcca aagttagata tagatgatat aaaaatagaa gatatgattg accaagatat
    11761 ggcaagacaa agtgagttga atttgccaga agttggtgaa ttagaattag ttagacatta
    11821 tacattatta tcaaataaaa actttggagt tgatacaggt ttttatcctt tgggttcttg
    11881 tactatgaaa tataatccta aaataaatga agatatggca gcacttccaa actttactgg
    11941 aatgcatcca taccaatctt cggatacagc tcaaggttct ctttctttga tgtatgattt
    12001 atcaagaaga cttgcagaaa ttacaggtat ggatgaagtt acactacaac cttcagcagg
    12061 ttctcatggt gagtttacag ggcttatgat tataaaagca tatcatgaaa atagaggtga
    12121 ccataagaga accaaagtga taattccaga ttctgcacat ggaacaaatc cagcaagtgc
    12181 agctatggca aactttgatg tgattcaaat agcatctgat aaaaatggag ctgtagacat
    12241 aaatgcatta aaagaggttt tgaatgatga agtagcagct cttatgctta ctaatccaag
    12301 tactcttggt ttatttgaaa aaaatataaa agaaatagct actcttgtac atgaagcagg
    12361 aggacttttg tactatgatg gtgcaaacat gaacgctatt atggggataa caagacctgg
    12421 agatatgggg tttgatgtgg ttcatcttaa tcttcataag actttttcaa ctcctcatgg
    12481 aggtggaggt ccaggagctg gtcctgttgg agttaaaaaa gaattagtac cttttttacc
    12541 aataccagta attgaaagaa aagaagataa gtatgtacta aattatgata gagaaaaatc
    12601 tattgggaaa attaaaaatt tctatggtaa ttttggagtt cttgtaagag cttacacata
    12661 tatactaact atgggaaggg atggacttaa agaggctagt gaaatggcag ttttaaatgc
    12721 taattatata aaggaaagta taaaagatga ttatattttg ccaatagata ccttgtgtaa
    12781 gcatgagttt gtattaggtg gattgccaag aggagaggcc aatataaaaa ctatcgatat
    12841 tgcaaaaaga ctactagatt atggatacca tcctccaaca atgtactttc ctcttattat
    12901 aaatgaggca cttatgatag aacctacaga aagtgagagt atagagacat tagatagttt
    12961 tatagaagct atgaaaagtg ttgctaaaga ggcaaaggaa gaaccagaac tattgaaaac
    13021 tgctccacat aatactttgg tcaaaagagt agatgatgca agggcagtaa agaaacctat
    13081 actaacatgg tcacaaagat aaatagttaa aaagtagaga tttaaagtat aaagagaatt
    13141 aaatttataa gaaaaagcta tctaacttaa tctagtttag atagcttttt tgtatattag
    13201 tatatatggt atttcctata taaagtttta aattgtatta gtgcttatat agaatattga
    13261 tatgatgatt atgtatagat attaataaga attgttaaat ttatcttgcc ttaactttat
    13321 ttactctttt atattaagaa aaacttaact aaaatatagc gaaattcata aaaatttagg
    13381 aaatcttaag aattataata tttaaatctt
//
LOCUS       DAEPUT010000105        13115 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.108, whole genome shotgun sequence.
ACCESSION   DAEPUT010000105 DAEPUT010000000
VERSION     DAEPUT010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13115
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.108"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            46..510
                     /gene="bcp"
                     /locus_tag="KRL22_003339"
     CDS             46..510
                     /gene="bcp"
                     /locus_tag="KRL22_003339"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBH1273781.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            520..1263
                     /gene="yaaA"
                     /locus_tag="KRL22_003340"
     CDS             520..1263
                     /gene="yaaA"
                     /locus_tag="KRL22_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBH1273782.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLQVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFDLEGYKYKENLSNNSEYIFVKE"
     gene            1391..4048
                     /locus_tag="KRL22_003341"
     CDS             1391..4048
                     /locus_tag="KRL22_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH1273783.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      4102..4204
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            4314..5579
                     /locus_tag="KRL22_003342"
     CDS             4314..5579
                     /locus_tag="KRL22_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HBH1273784.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            5609..6499
                     /gene="metA"
                     /locus_tag="KRL22_003343"
     CDS             5609..6499
                     /gene="metA"
                     /locus_tag="KRL22_003343"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBH1273785.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            6990..7433
                     /locus_tag="KRL22_003344"
     CDS             6990..7433
                     /locus_tag="KRL22_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1273786.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            7464..9281
                     /gene="ftsH"
                     /locus_tag="KRL22_003345"
     CDS             7464..9281
                     /gene="ftsH"
                     /locus_tag="KRL22_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH1273787.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            9459..12161
                     /locus_tag="KRL22_003346"
     CDS             9459..12161
                     /locus_tag="KRL22_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HBH1273788.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            12195..12893
                     /locus_tag="KRL22_003347"
     CDS             12195..12893
                     /locus_tag="KRL22_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1273789.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVNKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
BASE COUNT         5139 a         1510 c         2405 g         4061 t
ORIGIN      
        1 aagcatagta taaaattatt aataaaaaca aaaggagaga tatttatgtt gagtatagga
       61 acaaaagcac cagaatttac actagaagat aaagatggaa ataaggtaag tatgtcagat
      121 tttaaaggca aaaaagtagt agtatatttt tatcctaaag ataatacacc aggatgtaca
      181 cgtcaagctt gtgcttttag aaatgcatat gatggattta aaaaggaaga tatacaagtt
      241 attgggataa gtaaagatag tataaaatca catcaaaaat ttgcagaaaa gcatgaactt
      301 ccttttattt tactttctga ccctgactta gttgctataa aagcttttga tgtatggaaa
      361 gagaaaaaaa tgtatggaaa aactgcattg ggagttgtac gtgcgacata tattatagat
      421 gaaaatggaa ttattgaaaa agtctttgaa aaagcaaaac cagacacaaa tgcacaagag
      481 attcttgaat atttggaaaa acaggagtaa taagaattta tgattataat gttatcacca
      541 gctaaaaata tgaagaatat agaagtattt gatagagatt tgagtttgcc ttgctttata
      601 gataacacaa aagaaatagt ggaaaatata aagacatttg gtatagaaga ttttaaaaat
      661 aaaatgaaaa ttaatgaaaa attagctgta ttaaataaaa atagatttga aagcattaaa
      721 tttgatagat taggaaaccc tgcaatctta acttatgatg gaatacaata taaaaatata
      781 gaagcagaaa attttacaag gaaagatgaa gagtttgcaa atagctgtat tcgaatcata
      841 agtggattgt atggtgttgt aaaaccatat gatagtatat atgaatatag attagaaatg
      901 cagacaaaat tacaagtagg tgagtttaag aatttatacg aatattgggg aaatcgtata
      961 tataaagaac taatcaaaga gaaaacagct atcgttaatc tttcatcaaa tgaatacagc
     1021 aaatccatag aaaaatttat taaagatagt gatacatata ttacatgtac ttttaaagta
     1081 aataaaaatg gcatattgaa agtggaatct acacaagcaa agaaagctag aggtatgatg
     1141 acaaaataca ttgtaaaaaa taggataaga gatattgaag aactgaaaaa gtttgattta
     1201 gaaggttata agtataaaga aaacttatct aacaatagtg aatacatatt tgtaaaagag
     1261 tagaagtttt gttaaatatt aaatggcatt gttaaattta ggtaaaatat acttagtgtg
     1321 tattgaattg aacttgattt taaaatataa ttattcttaa attaaaaaaa gaaaggagtg
     1381 gtcttccaaa atggaaaatc acaaacagat gccttggcat tcaagagcaa cgcatgaaat
     1441 tttagaaagt ctagattcat cagaggaggg gctcaccgat accgaggcgg aaaaacggct
     1501 taaagagaat ggcttaaatg aacttagaaa aaaaccacct agaacaactt tacaaatgct
     1561 ttggagtcaa attacagatg ctatggttat gatactaata ggagcagcaa tattatcttt
     1621 gatatttggc gaatttacag aagcttttgt aatactaata attgtaacag taaatgcagt
     1681 tattggaatt gttcaagaga aaaaagcaga atcatcatta gaagcattaa aaaatatgaa
     1741 ttcacctaca gctcgtgtta tgcgtgatgg tgaagaaaat gttattccag caagtaatct
     1801 tgtagtagga gatattgttt ttttagaaga tggagctatg gttccagcag accttcgttt
     1861 aatagaaaca tcaagtttaa aaattcaaga ggcttcttta acaggagaat ctgttccatc
     1921 agaaaaagat gcagatacaa tcttacctaa agaatgtgta ttaggagacc gtagcaatat
     1981 ggcgtataca tcttcaatag tcacatatgg tagaggtgta ggtgttgtag tagcaactgg
     2041 tatggataca gaagtgggta acatagcaca tcttttagat tcacaagatg attttgatac
     2101 tcctataaaa cgtaaactta atactgttgg aaagacatta agtgtcatag gtattattgt
     2161 atgcgttgtt atatttgcaa taggtgcatt ttatcagaga cctctcttgc caatgtttat
     2221 gattgcaatt tcccttgcca tatcaattat tccagaggga ttacctgcaa cagctactat
     2281 tgtaatggct ttaggcgtac agcgtatggc taaaagaaat gctttaatta gaaaattacc
     2341 tgctgttgaa acattaggag gagctacagt aatatgttgt gataaaactg gtacgttaac
     2401 cttaaataaa atgactgtta cacatattgc tgtcaatgga gattttgaat ctggaaaagt
     2461 gacatcaata gatactgcat ctgaaaaaca tccattagtg tataaagaga ttgtttatgc
     2521 tggtgcactt tgtaatgatg catgtattaa tccagataaa acagatgaaa tattaggtga
     2581 cccaacagag ggcgcattaa tttttatggc caaaaaattt ggaatagatc aagaagctct
     2641 tgaagaagaa tatccacgtg tatttgaaca gccttttgat tcagatagaa aatgtatgac
     2701 aactgttcat aatatagatg aaaagattat tgcttatact aaaggagcag tagacgaaat
     2761 tcttgaccta tgtactaaaa tattaacttc aaaaggtgaa agaaacatta ctgaagtgga
     2821 taaaaagaat atacacgaat tatgtcttaa catgtctaaa gatgcattgc gtgtacttgg
     2881 ttttgctaag cgtgagattt catctatacc aaaagaagat agtgaaaata tagaatatga
     2941 tttaacattt ataggtatgg ttggtatgat tgacccacca agaactgagg taattgatgc
     3001 agtaagtact tgtaaagaag caggtataag aaccataatg ataacaggtg accataaagt
     3061 tactgccaca acaatcgctc atgagttagg aatatggagt gaagaaaata ctgtgatatc
     3121 tggtgatgaa cttgataatt tgagtgatga tgaactagat gaagctgtta aaaatactac
     3181 agtatttgct cgtgtatccc catttgataa acttagaatt atacaatctc taaaaagaat
     3241 tggagaagta ccagcaatga ctggggatgg tgtaaatgac tctcctgcct taaagtctgc
     3301 tgatattggt atagccatgg gtataagtgg tacagatgtt gcaaaagatt cttctgacat
     3361 gattttaatg gacgatagtt ttacaacaat tgcttatgca ataaaagaag gtagacgtgt
     3421 atatagaaac atacaaaaag ttatacaatt tttgcttgtt ggtaatatag cagagatact
     3481 tacgttgttt gtagcaatat tattaaattg ggatactccg cttcttgctg ttcatatttt
     3541 atgggtaaac cttgcaactg ctacgcttcc agcccttgct cttggagttg acccaccaag
     3601 cagaaatata atgaagcacc agccagtgaa atcaaccact ttgtttgaaa aaaatcttat
     3661 acaaagagtt gttacccaag gtatatttgt ggcaataatg actattttag catataaaat
     3721 tggtcttaat atagaaaatc attctgtagg tcaaacaatg gcattttgtg tattagcatt
     3781 ttcacagatg ttacgagcat ttagtcagcg ttcaaataca gattcaatgt ttaatagaaa
     3841 taatggtaaa aatccatttc ttttaatctc atttttaact tctgcatttt taatagcagt
     3901 aatactgttt gtacctgttt ttagaaatgc ttttaactta acagttttaa ataacttaga
     3961 gtggcttata acgattgttt tagccataat gtctgtaatt caagtagagg ttgggaaaat
     4021 tattaaaaga aaaaaattaa aaaaatagtt gacaaaatta ggaaaaatat ataagatata
     4081 aaacatagaa aaattaaata aatcttatcc agagaggtgg agggactggc cctatgaaac
     4141 ccggcaacca gtatatttat atacattggt gctaaatcct gcggcgaaag ctgagagatg
     4201 agtataatta agcttataca gagcctgagt tatatactca ggctttattt attttaactc
     4261 tcatctggta aatagtttaa ttttttttac taaaatctaa gggggataca agaatgtata
     4321 ataaagaaac aatatgtgtg caaggaaatt ataaaccagg taatggagaa ccaagagtac
     4381 tacctttata tcaaagtaca acttttaaat atagcagtat agaccaactt gctgaattat
     4441 ttgatttaaa agttgatgga catatatatt caagaataag caatcctact attcaagctt
     4501 ttgaagaaaa aataagttta ctagagggtg gagtatcttc tgtagctgta tcatcagggc
     4561 aatctgcaaa tatgttggca gttttaaata tatgtaaatc aggagatagt atactttgtt
     4621 cttcaaaagt atatggagga acattcaatt tactaggacc tagtcttaaa aaatttggta
     4681 tagatttaat atcgtttgac ttagattcaa gtgaagatga gatagtagaa cttgcaaagg
     4741 aaaatactaa ggttgtgttt gcagaaacac ttgcaaatcc aactcttgaa gtcatagatt
     4801 ttgaaaaaat agcaaatgta gctaagagaa ttaatgttcc atttattgtt gataattcat
     4861 tagcatctcc agtgctttgt aaccctttaa agtatggagc aaatatagtt actcattcta
     4921 ccacaaaata tttagatggg catgcttcaa gtgttggagg aattatagtg gatggtggaa
     4981 actttaactg ggataatgga aaatttccag aattagttga gccagaccca acatatcatg
     5041 gtataagcta tactcaaaaa tttggaaatg ccgcatatgc aactaaagca agagttcagt
     5101 tgcttagaga ctatggaaat tgtttaagcc cattcaatgc gtatcttact aatttaaatg
     5161 ttgaaacact acatcttaga atggagagac atagtgaaaa tgcacttaaa atagctagat
     5221 ttttagaaaa acatgaaaat gtagattgga ttaattaccc aggacttgaa gataacaagt
     5281 attatgagaa tgccaaaaag tatttatcaa gaggatgtag tggtgtttta tcatttggag
     5341 taagaggtgg gttagaaaat gccaaaaaat ttgtggaaaa attacagata gcatctttgg
     5401 ttacacatgt ttcagatgta agaacttgtg ttatacatcc agcttcaact actcatagac
     5461 aattaacaga agaacaatta attgcatctg gagtattgcc ttcactaata agattatctg
     5521 ttggaataga aaatgtagag gatttaatag ctgatttaaa tcaagcttta aatttctaat
     5581 attctaagag aaagagaagt gaaaagatat ggctttaata ctaccaaagg gattacctgt
     5641 tattaataaa ttattagatg aaggaataga tgtaatttat aaagaagatt ttaaaaagga
     5701 attaaagtat gaagaaaaca tagacactaa gatagctata ctaaatctaa tgcctataaa
     5761 gatagataca gaattagatt tactaagaag gatagataaa acaggattca acgtgtctgt
     5821 ggaatttatt aaaatttcaa caagagaaag taaaagaagt tgtaatgaat atgttaaaga
     5881 attttataaa acatttgatg aagccaaagg agagtatttt gatggcttta taataacagg
     5941 agctccagtt gaacaaatgg agtttgaaga agttgattat tggaatgaac tagaagaaat
     6001 tatggattat tctaagagaa aaactaaatc tacattatat atatgttggg cagctcaagc
     6061 aagtctttac aaatactaca atgtaaaaaa acttccacta agtcaaaaat gttttggagt
     6121 atttaagcat aaggtagata aagatagtaa aatagtagat ggatttgaaa atgaattttt
     6181 tgctccacat tcaagacata ctactgtaaa tattgaagct ttgaaagaga ataaagagtt
     6241 gagcattgtg agtcattcta aagaagctgg tccctatata attacaaatt caagagatgt
     6301 gttcgtaatg ggtcatagcg agtatgacaa atacactctt gataaagaat ataagaggga
     6361 tataaataaa ggagataaaa tatctatacc tcaaaattac tatattaatg atgacccttc
     6421 agaagagcca actgtaaaat ggaaaaaaca ttcagaattg ttgtttagaa attggataaa
     6481 aaactatttg atacaataaa ttttaagagt atataaatgt taactaaaaa aatatagaaa
     6541 tttataggta taaagttaat cttaatgata ctttatacct tattttttta aaatttgacc
     6601 ttataatagt agttttatat tttaagaaaa tcactttagg tgtatgtaga tagaggtggc
     6661 tttaatttta tatatggtgc gataatggga gactaaacct ttatagtatc aataaatttg
     6721 tattttaact tttaaaagag attaaaaagg gagaaatcag tgtaaaatat atatatagat
     6781 tttttattaa attttattaa aaatatcctg tataaaatta aatatcaata agataacaaa
     6841 atttcaattg aagttacaat attgtaattg acaataaata cttaacacta taatatttaa
     6901 tacattaaac attatagtgt taagtattta tttacagtat gcacttcagc ctaaatttga
     6961 aataaagtat tttcgtaggg agcgtttgta tggatgagat gagttttaag aaagagctac
     7021 tagagttgac tagagatata aatatgaaat ttacaacttt attaagtgat ttttatcagc
     7081 cacttggtat tacagcagtg caagctttga ttttatctga gttatgtgaa catggagaga
     7141 aaaaaataag cgatttaggg aagaacttaa acatgacaaa tagtaatgta tcagtaatct
     7201 gtcaaaggct tgaaaaaaat ggctttttaa atcgcataag agatatagaa gaccaacgaa
     7261 ttgtaaaagt aaaagttaca aataaatcat tggatataca agaacatatt tcaagtagta
     7321 tttttgatag ttattttgaa aatatgacca gtgaaaaatt gcaagatatg gaagatataa
     7381 tagaaggttt agagaaatta aataaacttt taacttacat tgattgcaaa taacataaaa
     7441 ataatttaaa ggagaataaa attatggatg aacataaacc ccaaaaaagg tcagcactct
     7501 attattatac agttataata atagtagtaa tgtttttaaa tgctttaata tttccaagtt
     7561 taatggataa aaaaatggtt gagattgact atggaaagtt tctcacaatg ttggatacag
     7621 gaaaggttaa atctgttgag atagaaaata atagaatagc aataaatcca tctagtagca
     7681 aggataagaa tatatacata actggtagaa tggatgaccc agaattggta gatagactaa
     7741 aaaatgcaaa agtagaattt actaaggtta ttcctaagga aaattcacct cttttaagta
     7801 ttttacttac atggataata cctataggta ttcttatgct atttggtaac ttaatgatga
     7861 agtctatgca aaagcgaatg ggtggtaatg ctatgcaatt tggaaaaagc aacgccaaaa
     7921 tgtatgtatc tgctcaaagt ggaaaaagat ttaatgatgt agctggtcaa gatgaggcaa
     7981 aagaagcttt aactgaaata gtagatttct tacacaatcc agaaaagtat aaaaagatag
     8041 gagcacaaat gcctaaagga gcacttttag taggacctcc aggtacagga aaaacactcc
     8101 ttgcaaaagc tgtagcaggt gaagcaaatg taccattttt ctcaatatct ggttctgagt
     8161 ttgttgagat gtttgtagga atgggagctt ctaggattcg tgatttattt aaacaagcaa
     8221 aagaaaaagc tccatgtata gtgtttatag atgagattga tactattggt aaaaagcgtg
     8281 ataatggaag tggattaggt ggaaatgatg aacgtgaaca aactttaaat cagttgttaa
     8341 gtgagatgga tggttttgat ggtggaattg gagtagtaat acttgctgct acaaatagac
     8401 ctgacagtct tgacaaagca ttacttcgtc caggaagatt tgatagacgt ataccagttg
     8461 aacttccaga ccttggagga cgtgaagcta tattaaaggt acatgctcaa aatgtaaatg
     8521 taagctcaga tatagattat aatgcaattg caaggtctac atcaggagca tcaggtgcag
     8581 aacttgcaaa tattgtaaac gaagcagcac ttttagcagt taagtctggc agagatatag
     8641 tagaacaaca ggattttgat gaatctgttg aaactgtaat tgctgggtat caacgtaaag
     8701 gagctgtaat ttcagacaag gaaaagaaaa ttatagcata tcatgaaata ggtcatgcac
     8761 ttgttgctgc tatgcaaaaa cattctgcac ctgtccataa gattactata atacctagaa
     8821 cttcaggagc attgggatat actatgcaag ttgctgaaga tgagagtgta cttatgtcta
     8881 aagaagaagc aattgataaa ataactactt ttacaggtgg tcgtgctgct gaagaggtta
     8941 tctttaacac ttgtacatca ggagcatcaa atgatataga acaagctact aaaattgcaa
     9001 gagctatggt tactcgcctt ggtatgagtg aagagtttga tatggtcgct cttgaaactg
     9061 taagcaatca atatttagga ggagatactt ctcttgcttg ttcttccgac actgctgcta
     9121 aaatagatga agaggtattt aaaatagtaa aggcttgtca caaaaatgca attgaaatct
     9181 tagaaaataa tattgataaa ttgcatgaac ttgctaatta tttattagaa aaagaaacta
     9241 ttacaggtga tgagtttatg gaaatactta acttaaacta aaatgattat acacaagata
     9301 aaaatgccta ttgttaggca tttttatttt acaactaaat tttttaaatt catatttaaa
     9361 tctttacata atcttaatca ttaaaaatac atcttaacta caattttata tcggaattga
     9421 tattataata gtaatgaatg gtgtaaggag gttttttaat ggatagacct aatcctgata
     9481 ttctattaga aaaaattaaa aatgaagaag aaaaactaag tagaggtcaa ttaaaaatat
     9541 tctttggtta tgcagctgga gtaggaaaaa cctactctat gttggaatct gcacaaaatt
     9601 taaaaaaagt gggtgtggat gtagtagttg gatatattga accacacact agaccagaaa
     9661 cattggcttt acttgatggc ttggaaattc ttcctgtaaa ggagatagaa tataaatcta
     9721 taaaactaaa agaatttgat ttagatgctg ctttagcaag aaaaccagaa gttatattag
     9781 tagatgaatt tgcccattct aatgttgctg ggttaaggca tacaaaaaga tggcaagata
     9841 tagaagaatt gctgttagca ggcataaatg tctacactac tgtaaatgta caacatttag
     9901 aaagtctaaa tgacattgtt gagataatta caaacgtatc agttaaagag actataccag
     9961 ataagttttt ggatacaaat acacagttag aacttataga tgttgaacct gatgtacttc
    10021 ttgaaaggtt caatgaaggt aagatatata agaaagaaca agctactaga gcaaaaaata
    10081 atttttttat aaaagataac ttggttgcac ttagagaaat cgcacttaga aaaacagcag
    10141 agagagttaa taaagaagtt caaatgacca gactatcaaa gggtgatgta actgtaatac
    10201 ctacatcaga tacacttctt gcatgtataa gtccatctcc atcttcagca aaagttatta
    10261 gaactgcatc cagaatatca gacagtacat ttgcaaaatg gatagcttta tatgttgaaa
    10321 ctccaaacac agcaagactt ccatttgatg aacaaaaaca actacaaaat aacctaaaat
    10381 tagctaagaa attaggtgga gaaataattg ttttacatgg tgaaaatata atagagcaaa
    10441 tacttagaat tgcaaaactg agaaatgtaa caaaaattgt aataggtaga aatcattcaa
    10501 gtaataaaag atttagtaaa agatttaaaa aagatatagt tgacaaatta attgatgaag
    10561 ttgattatat agatatacat ataattccat ataaatttgc ctcagatgtt aaatacaaac
    10621 ctaaaaagga taaatcatca ataaaatcta aatttaaaat tagcaaagtt gattttataa
    10681 aacttatatt tattactttg atgataagta ttttagcata tgcagtacaa agcatgggat
    10741 ttataagaga aaatatattg ttaatatata tgttgggtgt agttttagtt tctatgtgga
    10801 ctaaagggta tagtacaggt ataataagtt ctgtatttaa tatagttctt ttaaattatt
    10861 tttttacagc accattatat acattatcta tagcagattc aaactatata gtaacactgg
    10921 ttgtattctc gatagtaggt ataataacta gcactcttac gtctaagata cagcatgaag
    10981 cagaaactgc tgctaaaaga gaagaaaata caaaaatgat atatcaaata attaagggat
    11041 ttttaagatt atcaaataaa gatgatatag tgaacaaagg tatagaactt ttgtctctta
    11101 gcttaagtag agatgtaatt tgttatttaa atgtagataa gcataataaa tcaaagcttt
    11161 acaaaaaaaa tactaataat aaggataaaa atgatttgga tagtgaagat gaaaaagctg
    11221 ttgcaagttg ggttttatcc aattcaacag tggcaggaaa tgacacggat acacttcctg
    11281 gttcaaaggg atactatata ccaattgtag gaatgaattt aactttagga gtagtgggaa
    11341 tatcatgtat tgattcgaaa ttggatacag aagatataag cttaattgaa acaataattg
    11401 ctcaaatggc aatagcgctt gatagagaaa tcttgtcaga agctaaagaa aataccaatc
    11461 ttgagattga aagggaaaga ttaagaagta atcttttaag agcagtttcg catgacctta
    11521 gaactccact agcaggaata tctggtgcag taagtacaat tataaaaaac aagggtacta
    11581 taggtcaaga tataatagat gaattactta gtggtgtata tgaagatact cagtggttaa
    11641 taagacttgt tgaaaattta cttagtatga ccaagataga tgaagggaaa ttggaagtta
    11701 aaaaacattc tgaactggtt gaggaaatta tatcagaagc gttacaaaaa ataaaaaaaa
    11761 gaattgaaaa tgcacttata gatattaata taccagaaca gatattattt gttcctatgg
    11821 atgcaaaatt aatagaacaa gttttaatta atttaataga taattctttg aaatattcaa
    11881 aggaagattg taagatagag ataaatgtat atgagaaaga tgattatgtt tggtttgaag
    11941 tatctgataa tggtcctggt atatcaaagg aacttaaaaa gcatatcttt gacagatttt
    12001 ttactggaga agaaggagct aaagattcca gaaagggtgt tggacttgga ttatcaattt
    12061 gtaaatctat aattcaagct cataaaggtg aaattatggt agaaaacaat aaagataagg
    12121 gttcaacttt taagtttagt ttgcctaagg aaaatgaata gttttaaatt ttaaaattag
    12181 ttttggagga agaaatgagt aaaaaactta tattgttagt agaggatgat aagacaataa
    12241 gaaaatttat atctactgca cttttaacac aggattatga tgtcaaggag gctataactg
    12301 gaaaagaagg tatctctatt gctgtctcat attctccaga tgttgttctt ttagatttag
    12361 gcttagagga tatggatgga atagaggtaa taaaagctat cagacaattt tcaaatatac
    12421 caataattgt agtttcagct agagagcaag atagagacaa ggtagaagta tttgatgcag
    12481 gggcagatga ttacttaaca aaaccattct ccatagtaga gttattagca agagtaagag
    12541 tagcatttag acattcacaa gtagaagctc aacaaaaaga tgatgttaaa tctacgtttg
    12601 aagtaaataa attattgatt gattttgata aaagaaaagt tattgttgat gatgttgaag
    12661 tccatttgac acctattgaa tataatattc tttcattact tgcaaagcat catggaaaag
    12721 tgcttactca taattttata ataaaagaaa tatggggtag tgttataggg aatgagacta
    12781 agtctttaag ggtctttatg gcaacgttaa gacgaaaaat agaaaaacaa cctgcaaacc
    12841 caagatatat aattacagaa gttggtgtag gatacagatt aaatgatgaa tagttgtaat
    12901 atattaatta ttagattatg tgcttattaa tatatattaa aattatatag tttagttaaa
    12961 ataagaatga agtgtatgtg cttgttgtca gtttagcaca tgcattttat tttttagctt
    13021 ttttagtatc aataattttt tagtatcaat aatatgaaat atgttttaaa ataagtatat
    13081 agtgtaatct gtaataaaaa ctttggttaa ataat
//
LOCUS       DAEPUT010000106        12970 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.109, whole genome shotgun sequence.
ACCESSION   DAEPUT010000106 DAEPUT010000000
VERSION     DAEPUT010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12970
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.109"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            110..463
                     /locus_tag="KRL22_003348"
     CDS             110..463
                     /locus_tag="KRL22_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273790.1"
                     /translation="MAKRPVEKYDFKAFGEAIKAARTGRKESRKQVSDEMYISPRYLA
                     NIENKGQHPSLQIFFELMLRYNISVDQFLLDTPTQKDTKRRQLDALLDDMSDNGIRIV
                     TATAKEISEVEKEDK"
     gene            712..1041
                     /gene="mobC"
                     /locus_tag="KRL22_003349"
     CDS             712..1041
                     /gene="mobC"
                     /locus_tag="KRL22_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBH1273791.1"
                     /translation="MNGRKRKVQIKFYVTEEERVLIEQKMKLVPTQNMAAYLRKIAID
                     GYIIQTDHSDIKAMTAEIQKIGVNINQIAKRVNATGSVYQEDIEEIKGVLAEIWRLQR
                     LSLLKAR"
     gene            1002..2351
                     /locus_tag="KRL22_003350"
     CDS             1002..2351
                     /locus_tag="KRL22_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBH1273792.1"
                     /translation="MAVTKIKPVKSTLSKALDYIQNPDKTDGKTLVSSFGCSYETADI
                     EFEYTLSQARQKGNNLAFHLIQSFEPGEVDCEKAHAIGKQLADAATKGQHEYVLTTHI
                     DKGHIHNHIIFCAVNFVDYHKYNSNKRSYYGIRNMSDKLCRENGLSVVVPGKGSKGKS
                     YAEYQAEKVGTSWKGKLKIAVDTLIPQVASFEELLQRLQAAGYEIKPGKYISCRAPGQ
                     ERFTRLKTLGADYTEEAIKERIAGKRTKAAKAPKEQRGVSLLIDIENSIKAQESRGYE
                     QWAKIHNLKLAAKTMNFLTEHQIEQYADLVSRIEEITAENEKTADALKSVEKRLADMA
                     VLMKHVTTYQKTKPVYEAYRRAKDKDAYRAKNESSLILHEAAAKTLKASGVTKLPNLA
                     AMQEEYGKLQAQKEALYTDYGKLKKQVKEYDVIKQNIDSILRLEKEPERSRETERLQ"
     gene            2412..2681
                     /locus_tag="KRL22_003351"
     CDS             2412..2681
                     /locus_tag="KRL22_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005933799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273793.1"
                     /translation="MADQTIPDYETIRAAVAGETWAVEKVLMCYKDEIDRQATVKKRQ
                     PDGTFKLEIDEDMRQYITMKLIEALPQFPLEEMEREEKRNRDKKS"
     gene            2728..3021
                     /locus_tag="KRL22_003352"
     CDS             2728..3021
                     /locus_tag="KRL22_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273794.1"
                     /translation="MKQRQKETISTWLYEEYRRLWIEKGQEPHKRNNREIVAAVMEQI
                     EAAGIWLPEQEVTKYFYRRKTHYRNRIEKELQPKPEMQDKDSQTQKEQGAGSQ"
     gene            complement(3166..3531)
                     /locus_tag="KRL22_003353"
     CDS             complement(3166..3531)
                     /locus_tag="KRL22_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBH1273795.1"
                     /translation="MTGSKRLTPPQSRKVNSLVKKECCNCERGHCILLDDGEECVCPQ
                     LISYSLLCKWFQTAVLPLDKLLYAELFKTEDKKRCTECSTFFVSKSNSVKYCPDCRKR
                     ITRRQAAERMRKRRAAVTQ"
     gene            complement(3528..3734)
                     /locus_tag="KRL22_003354"
     CDS             complement(3528..3734)
                     /locus_tag="KRL22_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBH1273796.1"
                     /translation="MIRLTVEEMNLLSIYHEGSKAQLMENMTTALPFMDEDMRPFAER
                     TLQKISPLTENEYAELSIFAADEV"
     gene            complement(3737..4681)
                     /locus_tag="KRL22_003355"
     CDS             complement(3737..4681)
                     /locus_tag="KRL22_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273797.1"
                     /translation="MKLQKFENVDVIASLEAIMKQNTAFYQSDFDIDKQILQKAAVSP
                     VPEDKRLLWFSRPSGTCCFRERDVFLKDTRQHNTWRFYGEQTRDTILAYAVELTGTEQ
                     EKIKGNLYELDYLQHFREVIEKSIPADNYTLIYEHGELTKPAGQYFDGNTDPQLGKFI
                     RFEAQPNDPEALKSILREQQKKRTPHTQGDFQLHIAALHDRRIEAEARRIVENVKGLG
                     EPDSPEKTHCAVELSPYFVPLATDKDMERLLSMLPYKSLSFSTLEDRHGVYALIDKSE
                     RNKEMKKSRPSVRAQLQTEKSPKLPKKTAKSKHHELEV"
     gene            complement(4685..5287)
                     /locus_tag="KRL22_003356"
                     /pseudo
     CDS             complement(4685..5287)
                     /locus_tag="KRL22_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585091.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
     gene            complement(5615..5821)
                     /locus_tag="KRL22_003357"
                     /pseudo
     CDS             complement(5615..5821)
                     /locus_tag="KRL22_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009003583.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6803..9070)
                     /locus_tag="KRL22_003358"
                     /pseudo
     CDS             complement(6803..9070)
                     /locus_tag="KRL22_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585091.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
     gene            complement(9312..11402)
                     /locus_tag="KRL22_003359"
     CDS             complement(9312..11402)
                     /locus_tag="KRL22_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBH1273798.1"
                     /translation="MILVIAEKPSVAQTIAAVLGAKEKKDGFLTGSGYIVSWCVGHLV
                     GLAEAAAYGEQYKKWSYDSLPILPQEWKYTVAADKEKQFKTLKELIHRADVSEVVNAC
                     YAGREGELIFRFVYEMAGCKKPMRRLWISSMEDSAIKEGFSRLKNGEEYDALFASALC
                     RAKADWLIGINATRLFSVLYNHTLNVGRVQTPTLKMLVDRDAAITTFKKEKYYHVRLA
                     LSGAEAASERISDKAEADALKTTCEASRTVCTSLVKEKKTAAPPKLFDLTSLQREANR
                     LFGYTAKQTLDLAQALYEKRLLTYPRTDSAFLTDDMGDTAAGIIKLLCGKFSFMAGKD
                     FTPELAKVLNSKKVSDHHAIIPTMELSKTDLAALPESERNILTLAGARLLMATAAPHT
                     FEAVTAIFECAGQSFTARGKRVLSDGWKELDRRYRAALKNKPETDDADSDTEKTLPPF
                     TEGQTFENSAATVTEHDTTPPKPHNEASLLSAMERAGSEDTDPDAERKGLGTPATRAA
                     VIEKLVKGGFVERKGKQLLPTKDGINLVCVLPDTLTSPQLTAEWENNLTQIAKGKAEP
                     AAFMEGIEDMARELVKTYPFLSEADKGRFKEEKPELGKCPRCGSPVYEGKKNYYCSNK
                     ECIFTMWKNDRFFEERKVTFTPKIAAALLKSGKVNVKKLYSPKTGKTYDGTIVLADTG
                     GKYVNYRIELPKKK"
     gene            complement(11523..11843)
                     /locus_tag="KRL22_003360"
     CDS             complement(11523..11843)
                     /locus_tag="KRL22_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
                     /protein_id="HBH1273799.1"
                     /translation="MASSKEYLEFILGQLSELEEITYRAMIGEFIIYYRGKIVGGIYD
                     DRLLVKPVKSAISYMPTAPYELPYEGAKEMLLVDEVDNKEFLTGLFHAMYDELPAPKP
                     KKKK"
     gene            complement(12112..12840)
                     /locus_tag="KRL22_003361"
     CDS             complement(12112..12840)
                     /locus_tag="KRL22_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBH1273800.1"
                     /translation="MKNKLKKTLTALCAALILMGGFSVPAYAQGAATEPPAEDATNDS
                     GVIVEEKEETPPLTPKGNATLVDDYGGNKQLITVTTKSGNYFYILIDRAAEGEQTVHF
                     LNQVDEADLMALTENGEAAKKPESCNCTEKCEAGKVNTSCPVCVTSMTGCTGKEPTPT
                     PTEQPEEPKEKGGNPGVVLALVLFALLGGGAAFYYFKFLKPKQNVKGDTDLEDFEFED
                     YDEDEPETDTGETPEDEETEEETL"
     gene            complement(12830..>12970)
                     /locus_tag="KRL22_003362"
     CDS             complement(12830..>12970)
                     /locus_tag="KRL22_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006859297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBH1273801.1"
                     /translation="QLVRAMRLTPQELNAMLSGGGIPGMNAAPATEAADYEEQEENAD
                     EE"
BASE COUNT         3055 a         3184 c         3157 g         3574 t
ORIGIN      
        1 acgaacaata gcaagtatat aaatatgaat tattatggct atttagtgga actgtataga
       61 catatccaaa gagaaagggg aacagtaaaa tgtaactggg tgaataaata tggcaaaaag
      121 accggtagaa aaatatgact tcaaggcatt tggagaagct ataaaagctg cgcggacggg
      181 gcgcaaagaa agccgcaaac aggtaagtga tgaaatgtat atttctcctc gctatcttgc
      241 aaatatcgaa aacaaaggac agcaccccag tctgcaaatc ttttttgagc ttatgcttcg
      301 ttacaatata tccgtagacc agtttctttt agatacgccc acccaaaaag atacaaagcg
      361 gcggcagctc gacgctctcc ttgatgatat gagcgataat ggcatacgga ttgtaacggc
      421 aactgcaaaa gaaatttcag aagtcgaaaa agaggacaaa taaatgtgtc cggcaaattg
      481 aatatgattt aggaagcgtt gtaatcttta cagattgcag cgtttttctt ttgctctttt
      541 ttggcatata gagcattgcg ttgtagtaac cagtgaggaa aaaactttcg tagcaagcat
      601 aggaaaagag tacccttttc cgtattttcg ccctcccgtc ctgcggtgcg tcggttgaaa
      661 attgcttgtt gggaagtgtc ccaaaccctc aaagcggaaa ggagcgattg catgaacgga
      721 cgcaaaagaa aagtacaaat caaattctat gtaacagagg aagaaagggt gttgattgag
      781 cagaaaatga agctcgtccc tacccaaaac atggcggcgt atcttcgcaa gattgccatt
      841 gacggctata tcattcagac agaccatagc gatataaaag ccatgacagc ggagatacag
      901 aaaatcgggg tcaacatcaa tcagattgca aagcgtgtca atgcgacagg cagcgtctac
      961 caagaggaca tagaggaaat aaagggggtg cttgcagaga tatggcggtt acaaagatta
     1021 agcctgttaa aagcacgttg agcaaagccc ttgattatat ccaaaatccg gataagacag
     1081 acgggaaaac gcttgtgtcc tcttttgggt gcagctatga aacggcagat attgagtttg
     1141 aatatacctt gtcgcaggct cggcagaaag ggaacaactt agcctttcat ctgatacaat
     1201 cgtttgaacc gggagaggtg gactgtgaga aagcccatgc aatcggaaag cagcttgccg
     1261 acgcagcaac aaagggacag cacgaatacg tccttaccac ccacatagac aaggggcata
     1321 tccataacca catcattttt tgcgcggtca actttgttga ctaccataag tacaattcca
     1381 ataagcgcag ctactacggc atacggaata tgagcgacaa gctgtgtcgg gaaaacgggc
     1441 tgtccgtcgt cgttccgggc aaaggcagca agggaaaaag ctatgcagaa tatcaagcgg
     1501 aaaaggtcgg tacaagttgg aaaggcaagc taaaaattgc cgttgatacg cttatccccc
     1561 aagtagcaag ttttgaagaa ttgttgcagc ggttacaggc agcgggctat gagataaagc
     1621 cgggaaaata tatctcctgc cgcgctcccg gacaggaacg gtttacccgc ttaaaaaccc
     1681 tcggtgcaga ttatacagag gaagcaatca aagaacggat tgcaggcaag cgcacaaagg
     1741 cagcgaaagc tcccaaagag cagcgtggcg tatcgctgct tatcgacatt gaaaacagta
     1801 tcaaggcaca agagagccgg ggctatgaac agtgggcgaa aatccataat ctgaaactgg
     1861 cggcaaagac catgaatttc ttgacagaac atcagattga gcagtacgcg gatttagtca
     1921 gccggattga agaaataact gcggaaaacg aaaagaccgc agacgcatta aagagtgtgg
     1981 aaaagcgtct tgcagatatg gcggtgctga tgaagcacgt taccacctat caaaagacaa
     2041 aaccagtcta tgaagcatac cgcagggcaa aggataaaga cgcataccgg gcaaaaaatg
     2101 aaagcagtct gatactccat gaagcggcgg caaagacact gaaagcgtcg ggcgttacca
     2161 agctccccaa tctcgccgcc atgcaggaag aatacgggaa gctccaagcg cagaaagaag
     2221 ccctttacac tgattatggc aagctgaaaa aacaggtcaa ggaatacgac gttatcaaac
     2281 agaacataga cagtatttta agactggaaa aagaaccgga acggagcagg gaaaccgaac
     2341 gcttacagta gaaatatcta taaaagcgtg gtaggataaa gatattccaa tacagacagg
     2401 agcgtgaaaa catggcagac caaacaatac ccgattatga aaccatacgc gccgccgttg
     2461 ccggagaaac atgggcggtg gaaaaggtgc ttatgtgcta caaggacgaa atcgacaggc
     2521 aggcaactgt aaagaaacgt cagccggacg gaacattcaa actggaaatt gatgaagata
     2581 tgcgccagta tatcacaatg aagctgatag aagccctccc ccaatttccc cttgaagaaa
     2641 tggaaagaga ggaaaaaaga aatcgggaca aaaaatcata aaaaggtaga cgggaagctg
     2701 ctgcggatag ataagcagtt tcgacatttg aagcaacggc aaaaagaaac tatcagtaca
     2761 tggctttatg aggaataccg ccgcctttgg atagaaaagg gacaggagcc gcataaacgc
     2821 aacaaccggg aaatcgttgc cgctgttatg gaacagatag aagctgcggg gatatggctg
     2881 ccggaacagg aagtaacaaa atatttttac cgcaggaaaa cccattaccg gaaccggata
     2941 gaaaaagaat tacagccgaa gccggaaatg caggataaag acagtcagac acaaaaagaa
     3001 cagggtgcag gaagccagta atgacctccc gcaccctgtt cttttatagg tactgatttt
     3061 agaatgttac gcagtagaac cccgatttca agggaaaagg tattctgtat cgcctatgcc
     3121 agtttcacgc cgtttatgcc ctgtaaatca aggctttttt cgcccttatt gcgtaaccgc
     3181 cgcgcgtcgt ttcctcatgc gttccgctgc ctgtctgcgg gtaatccgtt tccggcagtc
     3241 cgggcagtat ttgacgctgt ttgattttga tacaaagaac gtgctgcact cggtacaacg
     3301 ctttttatcc tcggtcttga aaagctctgc atagagcaac ttatcaaggg gaagtacggc
     3361 ggtctgaaac cacttgcata gaagtgaata ggaaataagc tgcgggcaga cacattcctc
     3421 cccgtcgtcc aataagatac agtgtccgcg ctcgcagttg cagcactcct tttttacaag
     3481 gctgttgact ttccggctct gtggcggcgt gagccgctta ctcccggtca tacttcatca
     3541 gcggcgaaaa tggaaagctc cgcatactcg ttttctgtta gtggggaaat tttctgtaag
     3601 gtgcgttctg caaagggacg catatcctcg tccatgaatg gtagcgcagt cgtcatattt
     3661 tccataagct gtgccttgct tccctcatgg taaatactca acaggttcat ttcttcaacg
     3721 gtcagtctaa tcatgctcat acctccaatt cgtgatgttt tgattttgct gtctttttcg
     3781 ggagttttgg ggatttttct gtttgtaact gcgcccggac agagggacgg gactttttca
     3841 tctctttatt cctctcgctt ttatctatca gcgcataaac gccatgcctg tcctccaacg
     3901 tagaaaagga aaggcttttg taagggagca tggaaagcag ccgttccata tccttatccg
     3961 ttgccagtgg aacaaagtag ggagaaagtt ctaccgcaca atgggtcttt tcggggctgt
     4021 ccggttctcc aagccctttt acattttcca caatccggcg ggcttctgct tcaatccgtc
     4081 tgtcatgcag ggcggcgata tgtaactgaa aatccccctg cgtatgcggt gttcgttttt
     4141 tctgctgttc cctcaaaatg ctttttaagg cttccgggtc gtttggctgt gcttcaaaac
     4201 gtataaactt tccaagctgc gggtcagtgt tcccgtcaaa atattgtccg gcaggttttg
     4261 tcagctcccc atgctcataa atcagcgtgt agttgtcggc agggattgat ttttcgatta
     4321 cttcccggaa atgctgcaaa taatccagtt cataaagatt gcccttgatt ttttcctgct
     4381 ctgtgcctgt cagttccacc gcataggcaa ggatagtatc gcgggtctgt tccccgtaaa
     4441 accgccatgt attatgctgc cttgtgtcct ttagaaaaac gtcccgttcc cggaagcagc
     4501 acgtcccgga cgggcgggaa aaccacaaaa gccgtttgtc ctccgggaca gggcttaccg
     4561 ccgctttctg caaaatctgt ttgtctatgt caaaatcgct ctgataaaaa gcggtattct
     4621 gtttcattat ggcttcaagg gaagcgataa cgtccacatt ttcaaatttt tgtaacttca
     4681 taggtcagct cctttccaaa tcctgtgttt tctgtcttgc ctgtttcttt ggtgtctgtt
     4741 ctttcgctgc tttaagctgc gcccggatag agggcttttc ctgtttggca ggcttgccac
     4801 gttccttatc ggttttcaat gcttcggcgt attctgcaag ggaaatctgt cctccggctt
     4861 ttgctttttc ttccagttcc gcagcggtcg gggtgttgtt tatctgcccg tcaatcatgt
     4921 tgtaattttg ctcggtggtc tgctcggcag ctttcaaata gtttttcggc tgcaaaaact
     4981 ctggcacgtc cttatacccc aagctgtcta catagtgggc ggtgtcctgc ccgttctgat
     5041 gaagcaccac cacgtcggaa acggaaaggc tgtgtccctt aaaatctttc gggtggtcga
     5101 tattgaagcg ggtgtaaata tcttcaaggg acattcccgg cgtaaggggt gcggtataga
     5161 taagctcata attgcctctg tcaatgctgt ttcccgccgc ctgtatgcgg tcgtaaggct
     5221 caaagcgcaa gtcccgcgtt tctttgccgt tctttagctg ataaattccg aaagtgtcct
     5281 cgttcccata gagtaagaga gcttcccttg atggctcgct ttcccgtagt tcttgcttca
     5341 tggcgttgta ctcccgcagg gcttcccatg tttccttttc cacgccgaac aagccgcctt
     5401 tttgtgcgtg tgcctgtaaa tcctccaagg tatcaacaag cccctctgtg ccgtcctcat
     5461 agagaagata aacggacata tcctcatgga aaaggcgttc agcggcttcc tgctgaagcg
     5521 gaagcatacc gtcccaagca tagccgtatt cctgcatatc cttgacgctg attgtagggt
     5581 ctggcatagg gatttccggc gcggcggtct gcgtctttgc gtaaagctcc ttgacttctc
     5641 cctgtgtcag ctccccggcg gtaagctgcg ccataagctc tcggcatttc tccggcgttc
     5701 cgatatacaa aacgtcgcct atctttgctt tcccgtcctc ctgcggaatg taggcttgca
     5761 gcagatacag gttgtccctg ctgtcgctgc ggggatttgc gtgtaccttg taaatggctt
     5821 cctgttcggg ctttttctgc gccgcttctt tttgcgcccg gatatgcgcc cgctgtatct
     5881 cggtaggctt ttccccggta aagggtgcaa tcgccttgat ataatcagcc gcatagtagg
     5941 cgttactggt aagctgccgc tgccatgccc ctgctttggg cgaccaacgg aagccattac
     6001 tttttaaggc ttcccgcgtg gcttcgtccg gcttatcttc aaagaagatt tgcagacggt
     6061 tcgcttcggt gtttgcttcc accttgccgc cgtcaaattc ccaacccaca aaaccgattt
     6121 ccttttgctg tgaaagggat ttgatacggt cttttacgcg cctgatttct gcgctgttgt
     6181 tggataacgc ccaagtcgca aaaggcttgt cccccaaatg ccaactgctc gccatgtctg
     6241 ctttcagttt ttcaagctgt tccggcgaca aatgcgggca gccgtcaagg gtcttatgct
     6301 tgcggtagta ggcgtttacg gctttcatgg tttcctgcga tttttcaagg ttttccagtt
     6361 tcttctccaa cttctgtact gcctgcgggt cgtctgcgct gataccgccc atgccggtgc
     6421 tgcggatttt atcaagaagt ccttgtatgt cctgccattc ccggtaattg ctgtcgcggg
     6481 ctgcgttctg cttttctttc ttccttgtgg ggaagttaga gccgcccgca atgaggatag
     6541 agggaacacg cgcgtcaatc tcatagcctt tgttcatgtt cgccgccagt ttccgggcgt
     6601 aagtgtcaag caggctgtcg attttctcat ggtacatcgg gtctacccgt tgtttctgcc
     6661 tttctgcaag ctgtacggct tcatctacat agtgcctgta ttcagccgtc gcgctgcctt
     6721 gcttataatc agaaaagctg ttcatatcct ttgcacgttt ggcggcagct tcattgattg
     6781 tgtaataagg tgcggcgggg gctgcctgtc ccggctgtgt agtctgcggt gcttcgctgt
     6841 ttgcgcctgt atcagcttcc ggctcggtct gtgcttcttt ttcctgtacc ggggctgttt
     6901 cttcgggaag ctccggcgcg gctgcttctg cttcgggctg tatggtagct tcctgtgggg
     6961 tctgtgcctg ttcggtggtc tgttccttat cctgtgcctt ttggatttct gcaaaatgtc
     7021 cgtctatggt atcaatcaga cttgcggcgg tgctgcggat tgtttcaaga gagcctttca
     7081 gttctgcaag ttcttttccg ctgctccacc cggcgatata cccaaaagaa tagtcggacg
     7141 tatcaagccc gtaatgttga cagaccgcat aggcaacgct ttccgcctgt acctcgcggg
     7201 tgcggcggtc gggacgttcc ggcgcgtctt tgtctatgtc atggagtgtt gcatgggcga
     7261 tttcatggat tgcggtcttg atgttctgca attcgtccat accctcgttg atagagatac
     7321 gcttttcctc ataattgcag cgtcctttta cgccgccgct tagtgcttca aatcccatag
     7381 caaacgggga agtcctttca agggcagcga aaaaatcctg atactgttcc acgtcgcccg
     7441 taagctcctt tatcccaagg tcgggcaact ccttaccctc ggtctgcgac acgtcaaaaa
     7501 cagataccac acgaaaggcg gggatttgga tttccttttc ctcggtaacg gctttcccgt
     7561 tcttatcgaa aacaggcttt tgcgtgtccg ggtcgatttt ttccacctgt ttcttaacgg
     7621 taaagggcgc gggcgcaagt atcttgatag ctttttctcc cggctttaca tggcggtcaa
     7681 attccttttc ccattgttta tagcctttta caaggttgcc gccctgcatg gcgataagga
     7741 ttgtattgtt taggctgtaa tcatggaatt tagacatagt acgcagatag tcggcgtaac
     7801 ggtcgctttc ataaatcccc aaaatgccct gttccagtcg gtcggtaatc tctttcattt
     7861 tgtcggcggg cttttcggaa gataggataa tcgggagaac cgggggctgc tctgtggcag
     7921 tggtcggtat ggctgcggca gcgtcaaggt ctgcctgttc ctgcggctgc ggcgttaccc
     7981 ggtattcctc cggcacgtcg cgcccgtcat accactgtgt aaaggtgttg cggttgttgt
     8041 agatatatcc ctgctcggta aatctgcccc cgtcattgat agcagcgtcc cgcccgtatt
     8101 cctcatacat gaaataattt tttgcttctt ccggcagctc caactcgtcc agttcttcaa
     8161 tcagataatg cccgtaatct tcctcggttt ttacggacgg ataaatccag taacagtcaa
     8221 ggttttgtgc aaggtttata atgtcctgca agtcccttgt atggtcgccg tatgtgatag
     8281 ccgcagcaaa tttttcccgg tcgtcgtcaa actgcatttt caaaagttcg ctcaaatagt
     8341 tcagttcgtc aaggctttca agctcggtca atttccctgc cagtcctgca atagaggact
     8401 ggtattctgt gatatgcagt tccccgtagt ttttgccgtc tatcccgata cggtcaaaga
     8461 cttctttcaa atgctcggca gtcgtgggga atgataccca ttcgcccgca ggtctgccct
     8521 cggtgtactt tccaagatta gaaagatacc cgcttaaaat cgtttctgcc atgcgttcac
     8581 tcctttcgtt ttcaatcatg cggtgcataa gttcgtagtc ctctatgctc atgctcccgt
     8641 caaatagata ggggtcgggt tcttcgccgt cccggtaggc tttttcagag aaaggcagcc
     8701 ccgcagcgtg ggcggcggct cttgcttcct cgataagctc cggcggcagc ctgtcgtcgt
     8761 gggcttcgat aaattccccg atattgctat atccgttttc gtagtggcga cgcaccccgg
     8821 cggtcagttc gtcaaggttc ctgtcctcgc caagatagcc ggaataatag ccgtttacca
     8881 caacggcggc agggtcagcc tgcttgattt cttccatgcg gcttctgtcc tccgggtaaa
     8941 ggtagtcgcc catttcaagg tggaaatatt cggcgttcca agaacgtccc gttttccaaa
     9001 acgccaccca agcgataccg tcccgtaatt cttcttgata gtcctttacg gtgtcccgta
     9061 aacttgccat gtgtaacctc ctttccaaag ggcagcgcgg acgctgcatg ttccggtttc
     9121 atcattcagt accccgcgcc cgcgtttttg ccaaagattt tatagatttt ttcaagattt
     9181 cagagggtaa aaccctccac aaaacagagg gtttgggaca cttcccaaca agcaaaaatc
     9241 cccgccgttc tcggtagaga aagcagggat tttacggaaa agggtactct tttcctatgc
     9301 ttgctattca gttatttttt cttcggtagt tcaatgcggt agttgacata tttcccgccc
     9361 gtatcagcca atacgatagt tccgtcgtag gttttgcccg tctttgggga atagagcttt
     9421 ttcacattta ccttgccgga ttttaagagt gcagcggcaa tctttggggt aaaggttact
     9481 tttcgttctt caaagaaacg gtcatttttc cacatggtaa agatacattc cttattactg
     9541 caatagtagt ttttctttcc ctcatagaca ggagaaccgc agcggggaca tttcccaagc
     9601 tccggctttt cctctttgaa acgccccttg tcagcttcgg aaagaaacgg ataggtcttt
     9661 accaattccc gcgccatatc ctcgataccc tccataaatg cggcgggttc tgccttgcct
     9721 tttgcaatct gcgtcagatt gttttcccat tctgcggtaa gctgcgggct tgtcaaggtg
     9781 tccggcagga cgcacacaag gttgataccg tcctttgtgg gaagtagctg cttgcctttt
     9841 cgctccacaa aaccgccctt taccagtttt tcaatgacgg cggcgcgggt ggcgggagtt
     9901 ccaagccctt tgcgttctgc gtccgggtcg gtgtcctcgc ttccggcgcg ctccatagca
     9961 gagagcagcg acgcttcgtt gtgaggtttt ggcggtgttg tgtcatgctc cgttaccgtt
    10021 gccgccgaat tttcaaaggt ctgtccctcg gtaaatggcg gcagggtctt ttctgtgtcg
    10081 ctgtctgcgt cgtccgtttc gggcttgttc tttaaggctg cccgatagcg gcggtcaagt
    10141 tctttccacc cgtcggacag tacccttttt ccccttgcgg taaaggactg tccggcacat
    10201 tcaaagattg ccgtaaccgc ttcaaaggta tgcggtgcgg cggtcgccat gagcagacgc
    10261 gccccggcaa gggtaaggat attcctttcg ctttccggca gcgcagcaag gtcggtcttt
    10321 gaaagctcca tagtcgggat aatggcatgg tggtctgata cctttttact gttcagcacc
    10381 tttgcaagct ccggcgtgaa gtcttttccc gccataaaag aaaatttccc acaaagcagc
    10441 ttgataatgc ccgccgctgt gtcgcccatg tcgtcggtta gaaatgcgct gtcggttctc
    10501 ggataagtaa gcaaacgctt ttcatacagg gcttgtgcaa ggtcaagggt ctgctttgcg
    10561 gtataaccga acaggcggtt tgcttccctc tgtaaagaag taaggtcaaa gagcttcggc
    10621 ggggctgcgg tctttttctc tttcacaagg gaagtacaga ctgtccgcga tgcttcgcaa
    10681 gtcgttttta atgcgtcggc ttctgcctta tctgaaattc tttcacttgc agcttccgcg
    10741 ccggataagg caaggcgcac atggtagtat ttttctttct tgaaagtggt aatcgctgcg
    10801 tcccggtcaa caagcatttt taaggtcggg gtctgtacgc gccccacgtt caaggtatga
    10861 ttgtaaagga cagagaaaag gcgggtggca ttgataccaa ttaaccagtc agcctttgcc
    10921 ctgcataatg cggaagcaaa gagcgcgtcg tattcctcgc cgttcttcag acgggaaaag
    10981 ccctctttga ttgcgctgtc ctccatagag gaaatccaaa ggcggcgcat aggtttcttg
    11041 cagcccgcca tttcataaac aaaacggaaa atgagttcac cctcgcgccc tgcgtagcag
    11101 gcattgacga cttcggaaac atctgcccgg tgtataagct cctttaaggt cttgaattgc
    11161 ttttccttgt cagccgcaac ggtgtacttc cattcctgcg gcaaaatcgg taagctgtca
    11221 tagctccact ttttatactg ttccccgtag gcggcagctt ccgcaagccc taccaaatgt
    11281 cccacgcacc aagaaacgat atagccgctt cctgtgagaa atccgtcttt cttttccttt
    11341 gccccaagta cggcagcgat tgtctgcgct acactgggct tttctgcgat aactaaaatc
    11401 aatgataaat cctcctttcg ggtaaaagaa aagagcaacc gatttttcga ttgctcctac
    11461 aagtgattgt ataaaattgt gcgatatgaa atagtaaaat aatttgacaa accggaagtt
    11521 gtttatttct tctttttcgg ttttggggct ggcagttcat catacattgc atgaaacaag
    11581 cctgtcaaaa attccttatt atcaacttca tctaccaaca acatctcttt tgctccctca
    11641 tagggtaatt catacggagc tgtcggcata taactaattg ccgattttac tggtttaaca
    11701 agtaatctat catcatagat accgcctaca atcttgccac gataataaat aataaattct
    11761 cctatcatag ctcgataagt aatttcttct aactcagata gctgccctaa aataaactct
    11821 aagtattcct tgcttgatgc catatttcca cctcaaattc ttatttgttt aactctgtca
    11881 tttcctatgg ttggaacaat tatatcatat tccatatcgc aagtacatct ttttatcgtt
    11941 ccgtctgtcg tttggtttcc agttttctga tacagtaccc cacacaaggg gactgtccct
    12001 tgtaaggaca ggaagtgcaa gccgggggat aaggaacagg cggcgcatta tcacgccgcc
    12061 cgttcggttt ctgtatcatc atcttttcaa agggattgtc ggtaaacagg gtcatagggt
    12121 ttcttcctcc gtttcttcat cttcgggagt ttccccggta tctgtttccg gctcgtcctc
    12181 gtcgtaatcc tcaaattcaa aatcttcaag gtcggtatcg ccctttacat tctgcttcgg
    12241 ctttagaaac ttaaagtagt agaacgctgc gccgccacca agcagggcaa agaggactaa
    12301 ggcaagcact acaccgggat tgccaccttt ttctttcggt tcttccggct gctctgttgg
    12361 tgttggggtg ggttctttgc ctgtgcagcc tgtcatactg gtaacacata ccgggcagga
    12421 cgtgtttacc tttccggctt cgcatttttc cgtacagtta cagctttccg gctttttggc
    12481 agcttcgccg ttttcggtca gtgccataag gtcggcttcg tccacttgat ttaggaaatg
    12541 tacggtctgt tccccctcgg cggcgcggtc aatgaggata tagaagtagt tgccgctttt
    12601 ggtggtaaca gtgataagct gcttattgcc gccgtaatcg tcaaccagtg ttgcgtttcc
    12661 ctttggggta aggggcggcg tttcttcttt ttcctccaca atcacgccgc tgtcattagt
    12721 tgcgtcctct gcgggcggct ctgtggctgc gccctgtgca taggcaggga cagaaaaacc
    12781 gcccataagg ataagggcgg cacaaagggc agtcagggtc tttttcagtt tattcttcat
    12841 ctgcattttc ctcctgttct tcgtagtctg cggcttcggt agcgggtgcg gcgttcatgc
    12901 cgggaatacc gccgccggac agcatagcgt taagttcctg cggggtcaga cgcatagctc
    12961 gtacaagctg
//
LOCUS       DAEPUT010000107        12898 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.110, whole genome shotgun sequence.
ACCESSION   DAEPUT010000107 DAEPUT010000000
VERSION     DAEPUT010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12898
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.110"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            131..319
                     /locus_tag="KRL22_003363"
     CDS             131..319
                     /locus_tag="KRL22_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBH1273802.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(479..631)
                     /locus_tag="KRL22_003364"
     CDS             complement(479..631)
                     /locus_tag="KRL22_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HBH1273803.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(729..1205)
                     /locus_tag="KRL22_003365"
     CDS             complement(729..1205)
                     /locus_tag="KRL22_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH1273804.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            1424..2185
                     /locus_tag="KRL22_003366"
     CDS             1424..2185
                     /locus_tag="KRL22_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1273805.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(2445..4373)
                     /locus_tag="KRL22_003367"
     CDS             complement(2445..4373)
                     /locus_tag="KRL22_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1273806.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILDEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            4607..5059
                     /locus_tag="KRL22_003368"
     CDS             4607..5059
                     /locus_tag="KRL22_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1273807.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            5062..5370
                     /locus_tag="KRL22_003369"
     CDS             5062..5370
                     /locus_tag="KRL22_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH1273808.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTIAKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            5484..6590
                     /locus_tag="KRL22_003370"
     CDS             5484..6590
                     /locus_tag="KRL22_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH1273809.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAV
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMMGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            6665..9343
                     /gene="mngB"
                     /locus_tag="KRL22_003371"
     CDS             6665..9343
                     /gene="mngB"
                     /locus_tag="KRL22_003371"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH1273810.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRSFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDIIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(9660..11993)
                     /locus_tag="KRL22_003372"
     CDS             complement(9660..11993)
                     /locus_tag="KRL22_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1273811.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGGA
                     KNPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKVINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(11968..12684)
                     /locus_tag="KRL22_003373"
     CDS             complement(11968..12684)
                     /locus_tag="KRL22_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1273812.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
BASE COUNT         4818 a         1793 c         1668 g         4619 t
ORIGIN      
        1 tatgataata agaaattctt caatatgtgt aaggcaaata tatatttcta ttgcaaattt
       61 ttgttattta tgataatata aatatgtttt tagtctttaa atagttatca ttttaaggag
      121 gtgtgcgtag atggcaaaag tatgtagcgt atgtggtaaa ggtaaggttt ctggaaacca
      181 agtatcacac tcaaataaac ataataaaag aacatggtca gctaacttaa gaagcgtaag
      241 agcgattata gatggagctc ctaagagagt aaaagtttgt actagatgtt tacgttctgg
      301 taaaattgaa agagcttagt aaccacgttt aaaagcctac ttccgtaagt aggcttttta
      361 atttaatcat ttttactctt tctcataaat tttaggatta tacttgaaat ccattttggt
      421 aattttattg ttactacttt catcaatact caccccacac tttatagtta aaactatttt
      481 aacaaaaaaa taataatgct ccacatccaa taagtattaa tgcggtaagt gctgaccaaa
      541 tccagccagg aagcaacatt gacagaatta cagccattcc tgttgctaga caaagtattc
      601 ctagcaatac cttagacttg ttatttctca tggaacacct ccacatagaa cctgtatcta
      661 taaatatttt catattcaag tttatgcgac agttttccat tttagaccaa taaacacatt
      721 atgtaatttt aatttttcat actagaatta ttactgaact ccgatataga ttctacaata
      781 tccaaaattc ctttttttct acttaacctt tcaggtccac tatataaaac aactggtata
      841 actttaggaa gtttaaaatt tttatcttct atttcttcaa gacttttttt cataataaaa
      901 cttttccaaa tttgttctct atacgatttc aatcttggga caatttcagt atccatttct
      961 gtttgaaatt ctaacactat ataatgtgat actttgccgc ttttagaaaa taccttataa
     1021 attatatcaa cttcttttcc tttatattca catataaaag atgtttctaa ctctatattt
     1081 ttaagagtta attcttttgc tattgagaca cttgtaaaat tttgaatcaa acttaaaaaa
     1141 ctttctttat ctgaatacat tcttctgtac tcttctcgtt tttcattgct tctttttaaa
     1201 ttcatacagt tcctcctaga ctatagaccc tctatttttt agtaaagata gtctataaat
     1261 tttatttttt aattttcatt agtgagtatt gacagttgtg tgtaaaatat ccagtaaaga
     1321 tattttttta tatttttatt aaaagatata aatttttata ttttaatgta ttgacattta
     1381 cgttgcgtaa aagtgtatat ttaatttata ggaggtacta cttatggaat atacagttca
     1441 aaaattaagt aaactagctg gtataagtac tagaacactt agatattatg atgaaatagg
     1501 tcttcttaaa ccacttaaaa taaattcttc aggttatcgt atatatggtc aaaatgaagt
     1561 taataaactt caacaaatac ttttttatag agaattagga attaacttag aaaatataaa
     1621 aaacattata aattcaccaa acttcgatag tttaagtgcg ttaaaagaac accataataa
     1681 attactagcc aaaagaaagc aaattgattt actaatagaa aatgtaacta aaactatagc
     1741 tctgaaggag ggaaaataca ctatgacaga tatagaaaaa tttgaaggtt ttaaagaaaa
     1801 gatgattgat gaaaatgaaa aaaattatgg aactgaaatt agagagaaat atggtaaaga
     1861 tattatagat acatcaaata aaaaacttaa aaatatgtct aagcaagatt atgaaaattg
     1921 gcaaaaccta aatatcgaaa taattagtaa acttaaaaaa gcttttaaaa ctggtgatgc
     1981 ctctagtgaa ctggctcagg aagttgcaaa attacatcat aaatggttga gttacacttg
     2041 gaacacatac tctaaagaag ctcattcctc tctagcacag atgtatgtat atgatgaacg
     2101 ttttacatca tattatgata gagaacaacc tggattagct aagtttttaa gggatgctat
     2161 agtaatatat acaagagata aataatataa aataataaag gtggtgtctc aaaatgaact
     2221 ttttagttca tgagacactc ttttttgtat gaaatcagat atatttttat cattttatca
     2281 atgaaaaaca ggtttctctc tctattttga gacagaatct ttattgtata ataattataa
     2341 tcaatacaaa ataataacaa attatacaaa acttacttat actatttatg ctaaaaacaa
     2401 aaaatatttt attaaagttt ttaaaactta tgtaatataa aaatctatac tatagacttg
     2461 attatggaaa gaaaattatc aaaatcatta caattagata tactatctct aatatcattg
     2521 tcatgaatta tctttaaaag gatatcataa atggagttta tttttatata atcatcttta
     2581 tttatagcca acatcatgat taatttaaca gtagaatctt cactccaata tattggttca
     2641 tccaatatgg aaatacaaat cttagttctt atagagctta attccatagg atgaggtata
     2701 gctaaaaaat catctatatt ggtagaagat aaactttctc tgtaaaatac agattcagca
     2761 aatgatggaa atacaatttc actttgagtt aatttgttgc acatcaactt tataagctca
     2821 tctttatctt tgattttagg attaacaata aataaatttt tatcaaagaa attgtccaaa
     2881 agattactat aaatatggga attattagtg attgacttag atatattctc tatatctttt
     2941 tttaatagtt ttaaatccac taatacaata ggaatactat catgatttaa aggaattgtc
     3001 gatattatta tatctacatc tgacaattca ctagctaaaa attgattaaa tgatagacat
     3061 tgaagtatat ttattttatc atgaaaaact ttgtttaatt gaacctctaa taacctactt
     3121 gaaccatacc ctgaaccaca tactaatact acgtttttac acttaatatt actttgaaaa
     3181 aatctctcta ttccagcacc tatatgcagg gatacatatc caatttcatc ttctgttaaa
     3241 gagtaaatac tatttttaaa aactttttct atagcattta aagttatttc aaatgctaaa
     3301 ggataattac tctttattgt atttataagg ggattcacct tatttaaatt ataagattta
     3361 gaattgagaa ttgatttaaa gtgcagtact aaatcatcaa ataatacact atcatttcta
     3421 aggtcaaaag tatattgatt gttgattact tctaaaattt cttcaacata ctctataatt
     3481 ttagtatcta ccctattgga aacgttatcc aaaagagaac ttttagttat aaaatgatta
     3541 tatagataaa ctctgtctgc ctttgaaata attatagtat atttactctc aatataatta
     3601 aatatatttt caacagttgt attcgattga aaatctgtta aaacaacatc taaaacatta
     3661 tctaagcagt aaccatcaag tattctactt acagtaatag ctaaatggat aataaagttt
     3721 tttagattaa aatctaggaa attgatatta aatttattaa tttcacttaa cactaccctt
     3781 tgaagctcta ttaaatctac attattaaat aattctattt ctctatctgt aattccaatt
     3841 atatagtttt caaaattcct atttatcata ttattagaaa tacatcttcg aatatctatt
     3901 tccttacctt caactttaac tccataatat ggcttagaaa ctaatattaa attatacttt
     3961 gacaaaatag gctttattct ttttatgtca tttagtattg taaatttact cacatacaag
     4021 ctattagcta aatcttctag ttttatatat gtattgttat agagaatata ttttaaaata
     4081 tattgatttc tttctatagg agaatctggt atttcacttg aatccataat atcatcagat
     4141 attaatgcta gatactgttg gtataatgct aaattaagaa tatctatata atatccttct
     4201 ccttttttta ttttaataat agcaccattt ttctctaaag ttccatttat agaagtaata
     4261 tcatttctta tagttctctc actcactttt aaatgattac ttaaagtttt acaagtaatt
     4321 ttatcatcac tttcatttaa taatttaaac aacgtgagca atctcttgtg cataaatatc
     4381 cccccttata gaatttcttc taaattatac tatttacact catataatac aattactcta
     4441 ataaaattgt attataataa tttatttcca cttctatatg gaaattagtt attatcataa
     4501 tataaatttc catgtcgaag tggaaattag ttatatttaa tttaattagg ataatgatta
     4561 caatataaat ataagttaag acattatgaa tggagtggaa aaatatatgg tattacaaga
     4621 aaaatatata tttatagata aagacttaaa aagcaaagaa gaagtattaa attttattgc
     4681 agatagtgct tatatactag gtattacaac taataaagag gctcttttaa aagaccttct
     4741 aaaaagagaa aatgaatttc caacaggaat aaaagatgga tttgcgatac ctcatacaaa
     4801 aagtgtaaat gtaaaggaag cttccatact ctatattaaa acaactaacg agttagagtg
     4861 gaaaacttta gatgatagta aggttagata tgtatttagt ttgttagccc cacataaaaa
     4921 tgaaggaaat atacatttga aaactctatc taaattagcc acatgtttaa tggaggatga
     4981 ttttacaagt gaagttaaaa atgctagtga tgcaagtcat ttagtaaaat atataactaa
     5041 taaaatgaag gaggaataat tatgaaaata gtagcaataa catcatgtat agcaggatta
     5101 gcacacacac ctatggcagc aaaagcttta gaacaagctg catcaaaaat gggtcatgaa
     5161 atcaaagtag aacaacaagg tgctatggga cgagtaaata ctatagcaaa agaagaagca
     5221 caagatgcgg actttatact tatagcatct gaccaaacta tatctggaat ggaaagattt
     5281 gatggtaaaa aagtgataaa agtcaaaata ggtatagcgt taaaaaaacc agaagctgtc
     5341 ttaacaaagt gtatagaagc tatttcttaa taaaaaaatc tcactctaat atagaatgag
     5401 aaaaatcaaa aattaaaaaa ttgtctaatg taattataac atattatcaa aaaatataac
     5461 aaacttatat aggaggatta aaaatgagta aaaaaaataa atctctttta agtgaactta
     5521 agggacactt aatgacaggt atctcatata tgttgccact tgtaataggc tcatctttag
     5581 ttgtagctat cccaaagctt acagctttag cagtgggtat aacaagttta gatgcttata
     5641 aaaatgtatc tggtttttat catattcttt acttaatgga acaagttggt tggactggca
     5701 taggtctatt aaatacggta ttagcaggat ttatagcatt ttcaataggt gagaaaccag
     5761 ctatgggtgc aggttttatt ggtgggctca tagcaagtaa tactaatgca ggattcttag
     5821 gagcagtaat agcaggtttc tttgctgggt atgtttgtaa gtttttaaag aaaaaaatta
     5881 aaatatctgg gtcagcatca ggaatgatgc cacttataat aatgccactt ataacagttg
     5941 gattaactgg ttttttaatg agtgttgtat tagcaggacc tttaggaaac ataaatactt
     6001 cattaaatgc ttgggtagct gaaatgtgtc aaaatggaac aaattcggta gtattggctt
     6061 taattttagg tgcaatgata ggattcgatt taggtggacc agtaaataaa gcagcttgga
     6121 tggcaggaaa tgcattattg ttagagggaa tctatctacc agcgatattg gtaaactgcg
     6181 caatagttat acctccacta ggatatggtt tagctacatt cataagaaaa tcaaaatttt
     6241 ccaatgcatt agctgaaaca ggaaaaggca atatagttat gggcataatt ggaataacag
     6301 aaggtgcaat tcctttcact ttaacaaatc cattaaaatt agttcctgtt aatatgatgg
     6361 gatgcgcttt gggtgtagga ttatcagctt tgttaggtgt acatgctata atgcctccag
     6421 ttggtggatt atatggattt atatcaatag gttctggatg ggcttactta gtaggtgcaa
     6481 tatttggagc tttagtaata gcaatattat caacaacttt agtagacttc aatgaagatg
     6541 aaactacgga aaatacagaa tttgatgaaa tagagttaga tataatgtaa attaaaaact
     6601 taattttaga taattgagaa ttgagtgtac tctcaattct caattaaatt ttgggaggat
     6661 ttttatgaaa aagacaaaag tacatgtagt tccacacagt cattgggata gagaatggta
     6721 ttttacaaca tcaaggtcaa aaatatattt aatgaaagat tttcaagata tattagacat
     6781 attggaagaa aaagaagact ttaaatactt tactatggat gcacaagctt ctctcttaga
     6841 tgattattta aaatggagac ctcaggatga atatagaata agagatttag ttcaaagaag
     6901 aagattagtt attggacctt ggtatactca aacagaccaa ttggttatat caggagaatc
     6961 tataattaga aacctttact atggaataga tagatgcaat gaatttggtg aacctatgag
     7021 ggttggatat gtaccagatt cttttgggca atcagctcaa atgccacaaa tatacagaag
     7081 ttttggaata gatagttcat tattttggcg tggagtttct gatgatatgg tagatacaac
     7141 agagtttata tggaaaggtt ctgatggttc aaaagtatta gcagttcaaa taccatttgg
     7201 ttattactat ggaggtaata taccagaaga tgattcagat ttaaaagaat atttaaaaga
     7261 tataatcgga aaacttaagg ttaaagcttc tactaataac gtatattttc caaatggatt
     7321 tgaccaagca ccaataagaa aaaaccttcc tgatatatta aaaaaagcta atgaaataga
     7381 taatgaaaat gaatacgaaa taagtgatat agaaaactat atagattcag taagaaatga
     7441 aagaaatgaa tttacagagc ttaaaggtga atttttaaat gctaaacata tgagaataca
     7501 caaatccata ttctcctcaa ggtcagacct taaaataatg aataacaaat tagaaaatta
     7561 tattacaaat gtacttgaac cattattaac attaagttat tcacttggaa atgaataccc
     7621 tcacctagtt ataaaagata tatggaaact tatgtttgaa aatgcagctc atgacagcat
     7681 aggttcttgt aatagtgaca caacaaatga ggatgtatac acaagataca aacaagccag
     7741 agatttgagt ataaatttat tagatttgca tatgagactt ataagtactc aaatcaaaaa
     7801 taataatgaa gaaataacat taacagtatt caatggattc ccagaagtca gaaatgaagt
     7861 tgtagaattt gatacttata ttccaggtca agattttgtg ataaagaata aaaatggaga
     7921 aattcttaat tatataataa aagaaaaaga agatattaca aattatatat taactcaaac
     7981 aataagatta aacccaagta aaaaaatata tatacccaaa actgtatata gagcaaaaat
     8041 tgcactttca gtaaaagata taccaccaat gggatatact caactagttt ttgaattgga
     8101 tactaaaaat aaatgtgaaa tagaaacaag taattgcaaa gaaatagaaa acaaatacta
     8161 caaaataaca gccaataaaa atggttcatt agaaatatta gataaagaat ctaataaaac
     8221 ttataaaaac caagctgtaa ttgaagataa tggagatgat ggagattcat acaactattc
     8281 tcctccaaga aaagatattt atgtttcatc tttagattct gtatcttcag tagaagtgct
     8341 aaaatcaaac attcaagaag aaatgatact taaatattca ttgaccatac cagcttcact
     8401 ggaagaaagg gctataggta aagtttctgt gaaaatgcca gtaacaatga aaattacctt
     8461 agaacctaaa gaacaaataa ttaagtttaa tgttaatata aaaaataacc aagcactatc
     8521 tcatagagta agagttttat ttaatacaga aatagcatct aagttttcta tagcagatca
     8581 acaatttgga ataatacaaa gaccaacagt attagaaaaa gaccttgcat tgtggaaaag
     8641 agacaattac tcatggcaag aaaaacctat aactatcgaa ccaatgcaaa gttttgttac
     8701 tttagaggat ggacaaagag gaatagcatt aataactggt tgtgtaagag aatatcaaat
     8761 agttggtgat aatttagata taatagcatt aacactattc aggtcatttg gatatatggg
     8821 aagagaaaat ttactttata gaccaggaag agcttctgga gaaaaaataa tagcaacacc
     8881 agatgcacaa ttacttaaag agttaaactt tgactttggt ctttacatat ataacaataa
     8941 atttgatgaa gcaaatgtag ctaatacagc taagagattc ttaacaccta tacaaatata
     9001 tgaatatgct gattttttaa atggtagact tatatttgca ttcaatgacg aaaaacaaat
     9061 atatgaaaat gaatttagtt tgatgaatgt aaataattca aatttcacag taagtgcaat
     9121 aaagaaagaa gaaaaaggag atggaattgt agttagaatc ttcaatggta tgaaaaatga
     9181 ggatgctaag ggaagtctta acatcaataa aaatgtcaat gatgcttata gtgcaatgct
     9241 cgacgaaatc tatgataata ctagcaagct taaagtaaat actaaaactg tagaggtaaa
     9301 ttctttatca cattgtaaag tacaaacaat agtaattaaa taatataaaa tagcttatac
     9361 aagatttcaa aataaattgc tagtactatg ttaatagtaa agccagatat tatgctattt
     9421 ataagctctg taacactaaa taacattttg taaaataaaa aggtgaacct tgtatattag
     9481 gattcacctt ttttaaataa atcaacattc tgttttaaaa taacatttat aagctgtttt
     9541 gaaataatgc ttacaaatta ttttaaaaca atacctataa atttttattt aaagaataca
     9601 cataaatatt tccagactct tttatcctat agactttata attattaaag aagtctaatc
     9661 taatttttgt taaaagtaat tgtaacttta aataaatcac catccacact tatattcatc
     9721 ttaccaccct gtaattctat aaaacttttt gctattgcta aaccaagacc agaaccttct
     9781 gtgttacgtg atttatctcc tcttacaaat ctctccatta tatcatctac actaaaatca
     9841 atctcagatg cagacatatt tttaagcata atatttactt tattatctgt ttctaaaata
     9901 tcaatataca ctcttgaatt tggcattgca tatttgctta tatttattat aagattttca
     9961 aatactctaa atgtacgctg actatctaat ggtaatatta ttttttcatt agaaaagtta
    10021 ttctttacta ttagagatga atctgcaagt ttgtcatcta attctaaaag tgtctgcttc
    10081 attagagata caatatccac atttactata ttcaaataaa catctccact atttgccttg
    10141 cttacttcaa acaaatcttc tattagatgt tgcaatcttt gtgactttct gtctaatgta
    10201 tcaatataca acttacgatt ttcatctgtt atactttcat cttttaataa atctatataa
    10261 gtgattatag atgttagagg tgtttttaag tcatgtgata catttgatat aagctctgtt
    10321 ttcatctttt gactcttaac ctcttcgtca acagcttttt taaatccagt ttgaatattt
    10381 cctaattcgt cttttatagg attaaaaaat cctaaatctt tttccatatt tacatctaag
    10441 tttccatctg aaattttctt tgtaacatct aaaagttgat tatattcata tattgtcttt
    10501 ttagagtaat ctgacagtat cttaaataat actactgaat atattaatgc gagtattatt
    10561 ccaaagaacc acatactaca cattataact ataatcaata aatttattcc caaaattgta
    10621 actatagttt tatttggctt ttcttttaga tttattgttc taatttgatt aataactgtt
    10681 tttcctgctt tttttagcca tacaaaaaac attcctgtca cagtatgttt tgtaaaatac
    10741 tctcttattc caacatttaa aatatgtttt aaaagtatta taaatacaaa tattattgag
    10801 aatattacaa accaataagt taaattcatt aaacttacca atatactagc cattttagca
    10861 cttatatcat tgtttataag gtactctaca taattcccac tcaaggtatt acttattata
    10921 acagtaggat ataaatctac aagcccctgt ataatagcaa gagcaataaa gagtatctct
    10981 aacggtattc ttgataatgt atcaaatcct agcaactctt tagattttct atatgggaat
    11041 gctaaagcta caataacaac tatagctaat ataattttta aaatcattcc agaaatctta
    11101 taataagaat tattttctac attgcttata tatgaaatta taccatcatc aaaataagta
    11161 tttccataac catactctac actatcacct ttacttatta ctttaggtac agcatatact
    11221 aatgttatat tttttattgg agataactta tatgaaattg aatttcctcc taaacttgta
    11281 tccattaaat cttctcttgc tttagataac aacatttgat taataacttt ttgatttact
    11341 ccataagaat ccacaatatt tacttttcca tctttatcaa aattcattac aacgtagaat
    11401 ctatagtttt cttttatatc tgtaatttgc ttttgtcttt cctcatcatt catttctgta
    11461 ttttttgact gattttcatc agaattttct tttgaagcat cattctttgt tgtatcaagt
    11521 actcctaatt ctttattatc attaaaaaat tcaaaattgc tttctttatc aactaaatag
    11581 tactttaaat tctttcctga cgctttaatg aaatgctccc aattttcaaa gttttcatta
    11641 aaatctgcat taatactatc atctgtataa taagtttctg aaccatcata agtatctttt
    11701 tctttactta cattttttat atagttcata gtttcttcat tgataaatag ctttgatggt
    11761 tgtatcatct taccttcttg ttcttccttc atattatgat ataaaacata acttccttta
    11821 tatatactat ctacaaagct ttcctgttca aatggattct ttgctccacc tttagcacct
    11881 gcttgtatag tagaatattg actaatcata cctaatgatg ctgataacat aagtataaaa
    11941 actataatag taactatata tttatcttta aattttttca attttgtatc caacacccca
    12001 caccaccttt aaatatttag gattttttgg gtcaatttct atcttttccc ttatattcct
    12061 cacatgtacc ataactgtat ctgtatttac agcattctca ttccaaactc tttcatatat
    12121 ttcatcagca gaaaaaactc ttcctgcatt tctcataagt aaacttagta ttttaaattc
    12181 tataggagtt gtttttatat actttccatc aatactaact tcttttgtat tttcatttaa
    12241 ttctaatcca cctattgcaa acacactatc gtcactttct accttttgct ctttatttcc
    12301 aaccatgttt agatacttag tgtaccttct aagttgtgaa ttaactctag ccaatagttc
    12361 taatggctta aaaggttttg ttacataatc gtctgctcct atattaagcc ccattatttt
    12421 atcaacttct tctgattttg cagatagcat tattactgga aaattatagt tttctctaag
    12481 cttcattgta agtgttatac catccatttt aggcatcatt atatcaacta tagctaaatg
    12541 tatttcttgg ttttctataa ccttaagacc ttctaatcca ttgtatccct taaaaacatt
    12601 atatccttga tttaatagat atatttctat agcatctgct atctcctttt catcttctac
    12661 caccaaaata ttatatgaat tcattctaat ctcctttata ttaatttata aattttcttt
    12721 acatatatga ttatacaata tgatagaagt ttttccattt atatatatat ttatatcttt
    12781 tgttctggtt atttgtattt aatgtccatc ttagaaacct ccttctagtt taaatttaat
    12841 attttttcat tttgttttat atacttaata ttaaaattaa aaacttaaga tattacat
//
LOCUS       DAEPUT010000108        12867 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.111, whole genome shotgun sequence.
ACCESSION   DAEPUT010000108 DAEPUT010000000
VERSION     DAEPUT010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12867
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.111"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(499..687)
                     /locus_tag="KRL22_003374"
     CDS             complement(499..687)
                     /locus_tag="KRL22_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273813.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            complement(713..1852)
                     /locus_tag="KRL22_003375"
     CDS             complement(713..1852)
                     /locus_tag="KRL22_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH1273814.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKIIEDKNDLALESYYSSVIEGAFSNRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HIGLEPLKIYDFMSKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKEFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICSKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            2437..3348
                     /locus_tag="KRL22_003376"
     CDS             2437..3348
                     /locus_tag="KRL22_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273815.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKELSLKAKGLLSQMLSLPEDWD
                     YTLAGLSLINRESIDAIRTAVWELEKAGYITRQQGRDEKVKMTAIEYTIYEQPQPPAL
                     DCPVLENPTADNPILENPTPDNPTSENPTQLNKDIQKTDLSKKEKSNTDLSSNHSIPI
                     LSPNPSPLREETAEPERKGTEAADAYSVYEEIIKDNIEYEHFIKHTDIDRERLDEIVS
                     LILETVCTKRKTIRIAGDDYPAELVKAKFMKLNSSHIEFVFDCMKENTTKIRNIKQYL
                     KAVLFNAPNTIDSYYTALVNHDMYGGY"
     gene            3368..3586
                     /locus_tag="KRL22_003377"
     CDS             3368..3586
                     /locus_tag="KRL22_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBH1273816.1"
                     /translation="MTQKTGALIFDETADRYDIRFDLNDYYGGLHCGDCFEVFVRGKW
                     KPTRMEYGDNWYLVGVRASDLNGLRVRI"
     gene            3669..4145
                     /locus_tag="KRL22_003378"
     CDS             3669..4145
                     /locus_tag="KRL22_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBH1273817.1"
                     /translation="MQDEVNEKVVSLAIKTSKLTAEVLQKAMKALLAKGKGQLTKAPH
                     GKITMRQLMKPGEKVSNIEITDQNIKAFDPIARKNGLDYNVKKIENGKPPTYLVSFRG
                     KDIDVMTEAFREFTAKKLGRDKKPSIRKLLSTLKDKAAALNAQRDKVKKKDREVSL"
     gene            4142..4666
                     /locus_tag="KRL22_003379"
                     /pseudo
     CDS             4142..4666
                     /locus_tag="KRL22_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529212.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            4719..6362
                     /locus_tag="KRL22_003380"
     CDS             4719..6362
                     /locus_tag="KRL22_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004033175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1273818.1"
                     /translation="MRTATQTMKFTALYERLSRDDELIGESNSIKNQKQLLESYAHKN
                     GYSPIRHFTDDGVSGTTFEREGFQAMIAEVEAGNVSAVIVKDMSRFGRDYLKVGFYTE
                     VMFKEKGVRFIAINNGIDSANQQDSDFTPFLNIMNEWYARDASRKIQAVFKSRMQDGK
                     RVSPSVPYGYLRSPEDKQKLIIDEEPAAVVRRIYQMVIEGKGITAIADILTAEKVLIP
                     SAYAKIHCPENDHSKGFTNPYLWSATAVSYILEKQEYMGHTVLGKTISVSYKTKKRRK
                     AEPDELMIFKNTHPAIVDEETWHLAQKLRKTVRKPSYNRPPHPLTGLVYCADCSSKMT
                     HRQPSPTKKKKYDADDAYICGSYRQRTKDCTMHFIKTSVLWELILTAIREVSDYVRQD
                     EQAFIDKVQQTSIVQMAETQREQKRRLAEATERNEELNTLIKKLYEGNATGKIPDKHF
                     ERLLAEYDREQTALETEIEDLQEQIDSFDEDNTKVDKFIAVVRRYTDFTELTTPMLNE
                     FIEKVVVHEATGGRTDRKQKIDVYFNFVGQVELPPPDRA"
     gene            6420..6698
                     /locus_tag="KRL22_003381"
     CDS             6420..6698
                     /locus_tag="KRL22_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273819.1"
                     /translation="MRLSRYEKETIILLNAAEDTASIYTADPVWKRKLDKLVEKNPQC
                     YQCVKADEVSKTYSMPKRFISLRSKEKTVTLTDEQKKRAKQRLTRTDK"
     gene            6843..7220
                     /locus_tag="KRL22_003382"
     CDS             6843..7220
                     /locus_tag="KRL22_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004033173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBH1273820.1"
                     /translation="MSFPYFYGRAAEQYAFYRIPKLLFSDERFEALSTDAKLLYGMLI
                     DRMELSMKNGWTDKDGRVFIYFTLEDARERLKCGTEKIVRLFAELDSEKGIGLIECVR
                     QGLGKPNIIYVKNFMDDTSLYDW"
     gene            7475..7828
                     /locus_tag="KRL22_003383"
     CDS             7475..7828
                     /locus_tag="KRL22_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004083011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HBH1273821.1"
                     /translation="MKKMNYLGLLSLLSLIAILGWKTGNTGLYGFFGFAYYIRYFWVI
                     PDELFQQNVRKSTTFAFFAEMISLVPFMFICATLYDSSSAIPMAFGLSFATAILTFTV
                     VLMIQEWKERKGAQE"
     gene            7825..8019
                     /locus_tag="KRL22_003384"
     CDS             7825..8019
                     /locus_tag="KRL22_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004083009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273822.1"
                     /translation="MIKNRIKEYRAKHDMKQEDLAKLVGVRRETIGNLEKGRYNPSLV
                     LAWNIAKVFNVTIEEIFTVE"
     gene            8152..8571
                     /locus_tag="KRL22_003385"
     CDS             8152..8571
                     /locus_tag="KRL22_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1273823.1"
                     /translation="MNENIEILQRQFDAYCTKVLKYASISYYHANRRRMEHEVSFSSL
                     LEKDFAEVSTTDRYPCMLYRFQVREWLVEVQSEPLGHAIERLTPYRQEIILLYFFLGF
                     KNKEIAALYGCNAGKISYHKMRAVRQIRAEMEVRRHD"
     gene            8564..8806
                     /locus_tag="KRL22_003386"
     CDS             8564..8806
                     /locus_tag="KRL22_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273824.1"
                     /translation="MTKKYKDRYVPVEVIIAATQGEAAAIQTVLKTYESYIRNKCIKT
                     VYDERGLVYYGIDTDKKDFMERRLIHAVVENFKIDR"
     gene            8934..9353
                     /locus_tag="KRL22_003387"
     CDS             8934..9353
                     /locus_tag="KRL22_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC family protein"
                     /protein_id="HBH1273825.1"
                     /translation="MATSNIKASIPCDIHSVWKVVTEVKNYTWRSDLSKTEVISDKQF
                     IEYTKEGYPTTFTITITEPYKRWEFDMENSNMKGHWVGIFTSKDTETEIDFTEYVTAK
                     KLFMKPFVKSYLKKQQAQFVTDLKKAILCLMEEQNGI"
     gene            9343..9738
                     /locus_tag="KRL22_003388"
     CDS             9343..9738
                     /locus_tag="KRL22_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1273826.1"
                     /translation="MEYKVNDIKLVASTFIPFVNQIWKGNYDIERTQAALSKTLNITA
                     YDNKILVGCLRILTDGYFFGTITELLVLPEYQKQGVGSKLLELAKENTPTMLYFGAQP
                     GVEAFYEKNGCQKSLQSYIIEKPKEHITE"
     gene            9801..10103
                     /locus_tag="KRL22_003389"
     CDS             9801..10103
                     /locus_tag="KRL22_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HBH1273827.1"
                     /translation="MPEIRKEILTMTDIEEKIAKAEEEIRQLQNRKRKLLNQKKDAER
                     KARTHRLIERGAILESLLEKPEQYSNEQIKGLLEIAFQTAQAQEHLRKIKEENGEN"
     gene            10322..11815
                     /locus_tag="KRL22_003390"
     CDS             10322..11815
                     /locus_tag="KRL22_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HBH1273828.1"
                     /translation="MAIYHCSIKIVSRGKGKSAVAAAAYRSGETLTNNYDGVTHDFTR
                     KGGIVHTEILLPPHAPPDFADRSTLWNGVEKIEKAKNSQLAREIEIALPVELDREQQI
                     QLVREYVKENFVSVGMCADFAIHDKQDGNPHAHIMLTMRPLEQSGEWGAKSKKEYLLD
                     KDGQRIKLKNGTFKSRKVDTVDWNSQEKAEVWRQAWADIANRYLAAQDRPERIDHRSY
                     KRQGIEQIPTVHMGVAATQMERRGIVTDKGNQNREIREQNRLLKEVKRRIAALTAWIK
                     EKTAQTKENPFPSVPILSERSEQPPTLLELLNRAYTEAAKPQSRYGKIQDLKLYAKAF
                     NFLQSRNITTLVQLQEVVSDMKKQYWTTNGEIKQTEKLLHERKELIDQAEKYLEHHPT
                     YKAYMQTKPKKQEDFFESNRAALILYQSAERYLKEHLGEDKVLKPKAWKAEVADLTQK
                     KSRLYSDLQTLKAEVQEAEAVKKCVEQAVQPEQTKEKTQNKRRDMEL"
     gene            11876..12349
                     /locus_tag="KRL22_003391"
     CDS             11876..12349
                     /locus_tag="KRL22_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1273829.1"
                     /translation="MEYKIRQMKNTEYPLLNDFLYEAIYIPNGIEPPPKTVIYSPELQ
                     VYVSDFGQMKHDIALVAEIDKKIIGAVWVRIMNDYGHIDNTTPSLAMSVFKEYRGLGV
                     GTALLEELIATLKSKGYSQVSLSVQKDNYAVKMYQKVGFTILKEVDEEYIMVIAL"
     gene            12571..12750
                     /locus_tag="KRL22_003392"
     CDS             12571..12750
                     /locus_tag="KRL22_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HBH1273830.1"
                     /translation="MQENTQTATKTTAAPKPQTVKRKIGKTTYELSLHFSQTSTERMS
                     DKVMRLLENDLSVKK"
BASE COUNT         4181 a         2582 c         2742 g         3362 t
ORIGIN      
        1 aagtgctact ctttttacaa ataaatttta ttatttatac ttgtaattat atattaaata
       61 accaatttta tccatatgaa aaacaaataa ttacgatatt tttttaatta ttctttatat
      121 ttacatttta attcaaatta cttttgtaaa gattatatct gttgcatata ctactttaag
      181 tgctaatata tctcccccta aattagaatc ctcgttatct caatagacgt tttctactgt
      241 caaagttacc aacatttgaa acttattaaa tttttatata aaaaagacct agaatataaa
      301 ttccaagtca ttttttatta aatttatttt ttacaatata atattgtcat gattaaagaa
      361 cacaaatcat acacaaattg gtcataaatc ttacataaat catctacaaa aaatacatta
      421 tttatattaa atctatataa ctaaattaag agcatattgt acaatatgct cttagaaaag
      481 atatttcttg tttatagttt atagtttata gtatttctct atgattttta tttttatcat
      541 ttcaaaaata aaaattaaga ttacagttat tatcatattt tgtgtactat tttctataat
      601 attataatga aacaatgaaa aaacaataat taatgaaatt acgtttatag ccccagaaat
      661 caaaaatgcc tttttcttat tattcatata ttccctctcc agattatcta aactagtcta
      721 tatcaagcat ttttaagtac ttatcattaa ctttatatat atttttttct ttagacaaaa
      781 tctctatctc ttcaagatta ttaaacactt ccatcaactg gtcaactaat tcaatttcct
      841 ttattccagc ctttaagtat ctacttttat tcttttttat ataattttct aatgtcatag
      901 aatagttatc tttactacag atatatttta atatatgttc ttctgttgct gatagagtta
      961 tgtcattttc aaacaattcc tcttttaata tactttctaa agattttcta tcatgcatat
     1021 tacgcatctc attaatagat tgtattatag acttgagcat aaactctata aatacagtta
     1081 aattatttcc tttgttttct acatcaagta tagccttata atacttagtt ctgtttttag
     1141 atatcatata tgatattgaa aactccttga aagtatcata tcctttatca atcaaatata
     1201 gatatgataa ggctcttgat gttcttccat taccatcact aaaaggatga acatatacaa
     1261 agtaaaaatg aattatagca cttttaatta aattacttac tttgctattt tccataaaat
     1321 ctattaattt actcataaag tcatatatct tcaaaggttc aagccctata tgtataatct
     1381 caccttttga atcacataca tatacttttt cagttctata ctcatattct tctgaatcca
     1441 agcagttttc gcccaatata tgatgcaaat catatataaa tttgtgacta tataatttat
     1501 ctaagttgtc taatccatat tctaaggctc tatgattatt gtaaatcata tattcacttt
     1561 tattacttgg tttcatcttt cctctaatta tagattttgc aatctttcta tttgaaaaag
     1621 caccttctat tacactagaa taataagact ctagtgccaa atcattttta tcttctatta
     1681 ttttaaatat cttacttgat gttaatttat ctatttcatt tattaaattt aatatatttt
     1741 cagtttcatg atagtatagt tctttattat caaaactatt tatagaaagt acgattttat
     1801 ttccagtaaa gtatttgttt ttgtattctt ctattgtcag tttaatcacc accttagatt
     1861 atctttatct attaatatta acaaaaagta ttaattttta cactattttt gattatttgt
     1921 tttataatta tcaaactcaa tttaacgtta aagcataata aattttaata aataatgcaa
     1981 aaatttaaga ataagcattt aaaatatatg tcacaggaag tttacaacta ttatttcttt
     2041 taaattagtt gattatcttg aaaaatgctt gatttacggg catattcgca ggtttgcaga
     2101 ttgattttac tacttattta ctacttttaa cggattgcgc cttgatatgc aaaagcacct
     2161 gcggagctgc cggataaacc gctacaccac cttatgcggc acgtcgaaaa gaaaaaataa
     2221 aataagcacc acctataagg cggcgtttct cactcctaca caggagaaca ggaacgccgc
     2281 tatttttatg ccctcatgtt acgcagtaag gggcaaaaaa gccttgattt atgcggctct
     2341 taggacgtga aaatgagaaa ggcaagggtt gatacctttt ccctcaaaac cgcgtttcta
     2401 ttgcgtaaca aatccaacca aaggagtgat gaagctatgg cagttttccg cgtggaaaag
     2461 aataaaggtt atacggttat gagcaaccac catttacgaa acaaggagct ttccctaaag
     2521 gcaaaagggc tgttatcaca aatgctgtcc ttgccggagg attgggacta tacccttgca
     2581 gggctgtccc ttatcaaccg ggaaagtatc gacgctatcc gcaccgctgt atgggagctt
     2641 gaaaaagccg gatatatcac aaggcagcag ggacgcgacg agaaagttaa aatgaccgct
     2701 atcgagtaca ccatttacga acagccacag cccccggcat tggattgtcc ggtattggaa
     2761 aatccaacag cggataaccc gatattggaa aatccgacac cggataaccc gacgtcggaa
     2821 aatccaacgc aattaaataa agatatacaa aagactgact tatcaaaaaa agaaaaatca
     2881 aatacggatt tatcaagtaa ccattccatt cctatccttt cccctaaccc ctctcctttg
     2941 agggaggaaa cggcagagcc ggaacggaaa ggaacggaag cagcagacgc atacagtgtg
     3001 tatgaggaaa tcatcaagga caatatcgag tatgagcatt ttatcaagca tactgacatt
     3061 gacagggaac gcttggacga gattgtgtcc cttatccttg aaactgtctg caccaaacga
     3121 aagacaatcc gtatcgccgg ggacgattat ccggcagagc ttgtcaaagc aaagtttatg
     3181 aagctcaaca gcagccacat tgaatttgtc tttgactgca tgaaagagaa caccacgaaa
     3241 atccgcaaca tcaagcaata tctgaaagcg gtacttttca acgcacccaa caccattgac
     3301 agctattaca ccgcccttgt caatcacgat atgtacggcg gctattaaaa aacaggagga
     3361 ttttaatatg acacagaaaa caggagcttt gatttttgat gaaacggcag accgttacga
     3421 cattcgcttt gaccttaacg actactacgg aggattgcat tgtggggatt gctttgaagt
     3481 gtttgtacgc ggcaaatgga agccgacccg tatggagtac ggggacaact ggtatcttgt
     3541 gggtgtgagg gcttcggatt tgaacgggct gcgggtgcgt atctaaaggc ggcatgaaaa
     3601 atgtacgcct tatttttatg ccccgaagcg gcacaccacc ctaacaaaac catgaaagga
     3661 gggatttcat gcaagatgaa gtcaacgaaa aagttgtgtc tttagcaatc aaaacatcta
     3721 agctgaccgc cgaagtgctg caaaaggcta tgaaagccct gcttgccaaa ggcaaagggc
     3781 agctaaccaa agccccgcat gggaaaatca ctatgcggca gcttatgaag ccgggagaaa
     3841 aggtttccaa cattgagatt accgaccaaa atatcaaagc ctttgaccct atcgcaagga
     3901 aaaacgggct tgattacaac gtcaagaaga ttgagaacgg caagccgccg acctaccttg
     3961 tgtcttttag gggcaaggat attgacgtta tgaccgaagc gttccgggaa tttaccgcaa
     4021 agaaattagg cagggataaa aagccctcta tccgcaagct gctttccact ctgaaagata
     4081 aggcggcagc tctgaacgca cagagggaca aagtgaagaa aaaggacagg gaggtatcgc
     4141 tatgaagccg gaacttaaaa agctgcttat cctaaatgcc ccctatctgc tctttgtcta
     4201 tctctttgac aaaatcggac aggcggtgcg gctctctccg ggagctgacc tttccggcaa
     4261 ggtgctttcc cttgcagacg gcttttccgc tgcctttgca aacccgcttc cgagccttgt
     4321 ccctatggat ttgcttatcg gtattgcggg cgctgtcctt atccggctta tggtgtattt
     4381 caaaggcaag aacgcgaaga aataccgaaa aggtattgaa tacggttctg cccgttgggg
     4441 caacgccgaa gatataaagc cctacaccga cccggtattt cagaataatg tgctgctgac
     4501 acagacggaa cggcttacca tgaacagccg cccgaagcag ccgaagtatg caaggaataa
     4561 aaatatcctt gttatcgggg gaagcggcag cggcaagacg agattttttg tgaagcccaa
     4621 cttaatgcaa atgcacagca gctacgttgt aaccgatccg aaagggttaa tctattaagg
     4681 acagaggaaa taaagccgca gaaagtgagg tgcagagcat gaggacagca acacagacta
     4741 tgaaattcac agccttgtac gagcgtttaa gccgagatga tgaactcata ggcgagagca
     4801 acagtatcaa aaatcagaaa cagcttcttg aaagttacgc ccataaaaac ggctattccc
     4861 ctatccggca cttcacagat gacggagtaa gcggaacaac tttcgagcgt gagggcttcc
     4921 aagccatgat tgcagaggtt gaagctggaa atgtgagcgc agttattgta aaggacatga
     4981 gccgctttgg gcgtgattat ctgaaagtcg gtttttatac cgaagtcatg ttcaaagaaa
     5041 agggagtgcg gtttatcgct atcaacaacg gcatagacag cgcaaaccaa caggacagcg
     5101 attttacccc gttcttaaac attatgaacg agtggtatgc aagggacgca agccgcaaga
     5161 tacaggcagt tttcaaatcc cgtatgcagg acggcaagcg tgtttcccca agcgttccct
     5221 acggctattt gagaagcccc gaagataaac agaagctaat cattgacgaa gaacctgccg
     5281 ccgttgtgcg ccggatttat caaatggtaa tcgaggggaa aggcattacc gccatagcag
     5341 atattttgac cgctgaaaaa gtgctaatac cgtcagctta tgcaaaaatc cattgccccg
     5401 aaaatgacca cagcaagggc tttacaaatc cttatctctg gtctgctacc gctgtttcct
     5461 atatccttga aaagcaggaa tacatggggc atacggtact gggaaagaca atcagcgtca
     5521 gctacaagac caagaagcgg cgcaaggcag agccggacga actgatgatt ttcaagaaca
     5581 cccaccctgc tattgtggac gaggaaacat ggcatttagc gcagaagcta cgaaaaacgg
     5641 tcagaaaacc aagctataac agaccgcccc accccttgac agggcttgtg tattgcgccg
     5701 attgcagcag taaaatgacg caccggcagc caagccccac caagaaaaag aagtatgacg
     5761 cagacgacgc ttatatatgc ggcagttacc gacagcgcac aaaggattgt accatgcact
     5821 ttatcaagac ttccgttttg tgggaactga ttttaacggc aatacgggaa gtcagcgatt
     5881 atgtgcggca ggacgaacag gctttcatag acaaggtaca gcagacctct atcgtccaaa
     5941 tggcagaaac gcagagggaa cagaaacggc ggcttgcaga agccaccgag cgcaacgaag
     6001 aactgaatac cctaatcaag aagctgtatg agggcaacgc cacaggtaag atacccgaca
     6061 agcattttga acggctgtta gctgaatatg acagggagca gaccgcactg gaaaccgaga
     6121 ttgaggactt acaggagcag attgacagct ttgatgagga caacacaaaa gtcgataaat
     6181 tcatagccgt tgtgcggcga tatacggatt ttacggaact taccacccct atgctgaatg
     6241 agtttataga aaaggtggta gtccatgaag ccacaggcgg caggacagac aggaaacaga
     6301 aaattgatgt gtattttaac tttgtcgggc aggtggaact accgccgccg gacagggcat
     6361 gacaggcagg aaaggcactt cttagggagt gtcttttctc ttgccggaaa ggagcagata
     6421 tgagattgag ccgatatgag aaagaaacca ttatcctttt gaacgccgcc gaggacaccg
     6481 ccagtatcta caccgcagac cccgtatgga aacggaaact tgataaactg gtggagaaaa
     6541 atccacaatg ctatcagtgc gtcaaggctg atgaagtcag caagacctat tccatgccga
     6601 agcgatttat cagtttacgg tcaaaggaaa agaccgttac gctcacagac gagcagaaaa
     6661 aacgggcaaa acagagatta acgaggacag acaaatgagg gcgttttggg ggcgttctgc
     6721 gcttcataag ccctactcca atagcatttt aagaagccgg aaaccgcaaa aggtattagg
     6781 gtatacctgc cccatgatta tgccgtttgt gctgtttgag gtgggaaagg aggattgatt
     6841 gcatgagttt tccgtacttc tacggcagag ccgccgagca gtacgccttt taccgcatac
     6901 cgaagctgct gttttctgat gaacgctttg aagccctctc cacagacgca aaacttttgt
     6961 atggtatgct gatagaccgc atggagcttt ccatgaaaaa cggctggacg gataaggacg
     7021 ggcgtgtgtt tatctacttc acactggagg acgcaaggga acggctgaaa tgcggcactg
     7081 aaaagattgt caggctgttt gcagagttag acagcgagaa aggtatcggg ctgattgagt
     7141 gtgtccggca gggcttagga aagccgaata ttatctatgt caagaacttc atggacgata
     7201 cttccctcta tgactggtag gtatgggagg gaaagggttt gggaaaggaa aggattgata
     7261 gataagtctg ttatacttgt attgatataa tcagttttat acacttcgat aaccgaaatt
     7321 ccagaacttc ggaaatcgaa actcttgaac ttcgataatc gaaagtcaag aactacggaa
     7381 accgaaatac agaggtattg actttcattt ttgctcgtgg tatatttata acatgaagat
     7441 agaaatatac cacattcaga gcggaggata ttttatgaag aagatgaatt atttaggact
     7501 tttatcatta ctttctctaa ttgctatatt agggtggaaa actggaaata ccggattgta
     7561 tggatttttt ggttttgcct attacattcg ttacttttgg gttattccag atgagctatt
     7621 tcaacaaaat gttcggaaat ctactacttt tgcctttttt gcagaaatga tttcccttgt
     7681 tccgttcatg tttatttgtg caacgcttta tgatagttct tctgctattc ctatggcttt
     7741 tggactaagt ttcgctactg ctattcttac atttacagtt gttttaatga tacaggaatg
     7801 gaaagaacga aaaggggcgc aggaatgata aaaaatagga ttaaggagta cagagccaaa
     7861 catgatatga aacaggagga cttagccaag ttagtcggtg tacgccggga aacgataggc
     7921 aatcttgaaa aaggcagata caatccgtct ttggtgttag cgtggaatat cgcaaaagtg
     7981 tttaatgtga caatcgaaga aattttcaca gtagagtaaa agaaagaagc gttttttggt
     8041 atgccatatc aaatgacgct tcttgttgtt tacaggagta ccgttgccgt tccccacctc
     8101 tcctgtctgc tttgcgtaac tatcacacga acagacagga ggaaaatcaa aatgaatgaa
     8161 aacatagaaa tcttacaacg ccagtttgac gcatactgta cgaaagtctt gaaatatgct
     8221 tctatcagct actaccacgc caaccgccgc cgcatggagc atgaagtgtc cttttcttcc
     8281 ctactggaaa aggatttcgc cgaggtcagc accacagacc gctacccttg tatgctttac
     8341 cgtttccaag tgagggaatg gcttgtagag gtgcagagtg agccgttagg acacgccata
     8401 gaacggctta ccccatacag gcaggaaatc atcttactgt actttttctt aggtttcaag
     8461 aataaagaga ttgccgccct ctatggctgt aatgccggaa aaataagcta ccacaaaatg
     8521 agggctgtcc ggcagatacg ggcagaaatg gaggtgcgcc gccatgacta aaaaatacaa
     8581 agaccgctat gttcccgttg aagtaatcat agccgccaca cagggggaag ccgccgccat
     8641 tcagacggta ctgaaaactt atgaaagcta tatccgcaac aaatgtatca agacggttta
     8701 tgacgaaagg gggcttgtgt actacgggat agacacagat aaaaaagact tcatggaacg
     8761 ccgcttaatt catgctgtcg tggagaattt caagatagac agataaggcg aaagtacaag
     8821 acaggggcag tcagaaaaaa gctgattgtc cttgtcgaat agggatagga aacacaagcg
     8881 aggcatggta aaataaagac atcaaaaacg gagtttgtgc ggaggtgtta aaaatggcaa
     8941 cttcaaatat taaagccagt attccttgtg atattcatag cgtatggaaa gttgttacag
     9001 aggttaaaaa ttacacatgg cgtagtgatt tgagtaaaac agaagtcata agcgacaagc
     9061 agtttatcga atataccaaa gagggctatc cgaccacctt tacaatcact attacagaac
     9121 catataagcg ttgggaattt gatatggaaa acagcaacat gaaaggacac tgggttggta
     9181 tttttacttc caaagatact gaaacggaga ttgattttac agagtatgta acagcgaaaa
     9241 aattatttat gaaacctttt gtaaaatcct atctaaaaaa acaacaggcg caatttgtta
     9301 ctgatttgaa aaaagcaata ttatgcttaa tggaggaaca aaatggaata taaagtaaat
     9361 gatataaaac ttgttgcttc aactttcatt ccctttgtca atcaaatatg gaaaggcaac
     9421 tatgatatag agcgcacaca agccgcatta tctaaaacgc ttaatattac agcgtatgat
     9481 aataaaatac ttgtagggtg tttgcgtatt cttacagacg gatatttttt cggaacaatt
     9541 acagaattac ttgttcttcc agagtatcaa aaacaaggcg taggcagtaa acttcttgaa
     9601 cttgcaaagg agaacactcc aaccatgttg tattttggcg cacagccggg tgtagaagca
     9661 ttttacgaaa aaaacggctg tcaaaaaagc ctacaatctt acataataga aaaacccaag
     9721 gaacatataa cggaataacc gctaccctca cagtagcacc accgagcagg aaatcccgaa
     9781 acggacttcc tgcttttctt atgcccgaaa tcagaaagga gattttaacc atgacagaca
     9841 ttgaagaaaa gattgcaaaa gccgaggaag aaatccggca gttacagaac agaaagcgga
     9901 aacttctcaa tcagaaaaaa gacgcagaac gcaaggcgag gacgcaccgc cttattgagc
     9961 gtggggcgat actggaaagc ctgttggaga agccggagca atacagcaac gagcagataa
    10021 aaggcttgtt ggagattgct tttcagaccg cacaggcaca ggagcattta cggaaaatca
    10081 aagaagaaaa cggggagaat taaatctccc ttgcttgaca agggcgcact tatacacctt
    10141 tacaggtgtg tgcgctctgc cgagggctta tatcagcgtt ccgctgatac aggggagcta
    10201 cactcccctg cgggaatttc attccctacc ccttgtgtac ttcacgccag acgataccct
    10261 gctttgcagt ctatcgtctg ccatgaagtc tgaatatgcc gcccgaaagg aggttgacag
    10321 cgtggcgata tatcattgca gtattaagat tgttagcaga gggaaaggca agtcagccgt
    10381 tgccgccgcc gcttaccgaa gcggagaaac cctcacaaac aactatgacg gcgttaccca
    10441 tgactttacg aggaaaggcg gtattgtgca tacggaaatc ctcttgccgc cccatgcgcc
    10501 gccggatttt gcagaccgtt ctaccctatg gaacggcgtg gaaaaaatcg agaaagccaa
    10561 gaactcacag cttgcaaggg agattgaaat tgccctgccc gtagaacttg acagggaaca
    10621 gcagatacag cttgtacggg aatatgtgaa agaaaatttt gtgtctgttg gaatgtgcgc
    10681 cgattttgcc attcacgata aacaggacgg aaaccctcat gctcatatca tgcttaccat
    10741 gcgcccgttg gagcagtccg gcgagtgggg agcaaagtca aaaaaggaat atcttttaga
    10801 caaggacggt cagcgtatca agttgaaaaa cggcacattc aagagccgca aggttgatac
    10861 ggttgactgg aacagccaag agaaagccga agtatggcgg caggcgtggg cggatattgc
    10921 gaaccgctat cttgccgcac aggacagacc ggaacgcata gaccaccgtt cctataagcg
    10981 gcaaggtata gagcagatac cgaccgtcca catgggcgtt gccgctaccc aaatggagcg
    11041 caggggcatt gttaccgata aaggcaatca gaacagagaa atacgggaac aaaaccgtct
    11101 gttaaaggag gtcaaacgcc ggattgccgc cctcacagca tggataaaag aaaagaccgc
    11161 acagacaaag gaaaatcctt tcccttccgt tcctatcctt tccgagcgtt ccgaacagcc
    11221 gcccaccctt ttagaattgc ttaaccgagc ctatacagaa gccgccaagc cacagagccg
    11281 gtacggaaaa atccaagact tgaagctgta cgcaaaggca tttaatttct tgcagagcag
    11341 gaacattact acccttgtgc agttgcagga agttgtatcg gatatgaaaa aacaatactg
    11401 gactaccaac ggggaaatca agcagacgga aaagctactc catgagcgaa aggaactgat
    11461 agaccaagcc gagaaatatt tagaacacca ccccacctac aaggcgtata tgcagaccaa
    11521 gcccaagaag caggaggatt ttttcgagag caaccgagcc gcattgattt tgtatcagag
    11581 tgctgagcgt tatctcaaag agcatttagg ggaagataag gtgctgaagc cgaaagcatg
    11641 gaaagccgaa gttgccgacc ttacccaaaa gaaaagccgc ttgtatagcg atttgcagac
    11701 cttgaaagcg gaggtgcagg aagccgaagc cgtcaagaaa tgcgtggaac aggcagtaca
    11761 gccggagcag accaaagaaa agacgcagaa caaacggcgt gatatggaat tgtgattgtg
    11821 acggataagt gataaaatga tgatatgatt aaaagaaatt aaggagagtt gtgttatgga
    11881 atataaaata cgacaaatga aaaatacgga atatccatta ttgaatgatt ttttgtatga
    11941 agctatctat attccaaacg gtatagagcc gccgcctaag acagtaatat attcccccga
    12001 attgcaggtg tatgtttctg attttggaca gatgaaacat gatatagctt tagtcgcaga
    12061 aatagacaaa aaaataatag gtgctgtttg ggtgcgtatt atgaacgatt acgggcatat
    12121 tgataatact acaccctctc ttgcaatgtc tgtttttaag gaatatcgag ggttgggagt
    12181 aggtacagca ttgttagagg agttaattgc aactttgaaa tcaaaaggat attcccaagt
    12241 atcgttatcc gttcagaaag ataattatgc agtaaagatg tatcaaaaag ttggatttac
    12301 gattttgaaa gaagttgatg aggagtatat catggtaatt gctttatagt tacgcagtag
    12361 gcggcttgaa acacctattc cacaaggctt tttaagtatc aaaatcacaa agacggtatt
    12421 ttatatctct accctcaaaa acaggcttct attgcgtaac acaaccattg aaaactgaat
    12481 aaccgctacc ctcacagtag caccatcgag taggaaatct tgaaacagac ttcctgcttt
    12541 ttcttttgcc aaaatcagaa aggagagcct atgcaggaaa acacacagac agccactaag
    12601 accaccgccg ccccgaagcc gcagaccgtc aagcggaaaa tcggaaagac cacctatgaa
    12661 ttatcgcttc atttcagtca gacaagtaca gagcgcatga gtgataaagt catgcggcta
    12721 ctggaaaatg acctatccgt aaaaaaatga ggaaaacttt tctctatgtc cttgacaaac
    12781 agaccgaaaa ggtacggttt tagtcgagtg cgggaagctc ttacagcgcg gcgggtatcg
    12841 gataaaggta ctgaacacga taaattt
//
LOCUS       DAEPUT010000109        12745 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.112, whole genome shotgun sequence.
ACCESSION   DAEPUT010000109 DAEPUT010000000
VERSION     DAEPUT010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12745
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.112"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            140..1630
                     /locus_tag="KRL22_003393"
     CDS             140..1630
                     /locus_tag="KRL22_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1273831.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            1910..3406
                     /locus_tag="KRL22_003394"
     CDS             1910..3406
                     /locus_tag="KRL22_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1273832.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            3540..4454
                     /locus_tag="KRL22_003395"
     CDS             3540..4454
                     /locus_tag="KRL22_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1273833.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTNESYLKS
                     DKNDVSQNNIQSSTKNTAFKTTILSTGKSDCILVEIGNKVIMIDTGEDKNGKQIVDRL
                     KEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDSLKKA
                     DIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGDAEEE
                     RLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGVLKIL
                     ERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            4572..4763
                     /locus_tag="KRL22_003396"
     CDS             4572..4763
                     /locus_tag="KRL22_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273834.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            4986..5336
                     /locus_tag="KRL22_003397"
     CDS             4986..5336
                     /locus_tag="KRL22_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273835.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            5597..7102
                     /locus_tag="KRL22_003398"
     CDS             5597..7102
                     /locus_tag="KRL22_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBH1273836.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            7492..8589
                     /gene="dinB"
                     /locus_tag="KRL22_003399"
     CDS             7492..8589
                     /gene="dinB"
                     /locus_tag="KRL22_003399"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBH1273837.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            8852..9988
                     /locus_tag="KRL22_003400"
     CDS             8852..9988
                     /locus_tag="KRL22_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273838.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            9981..11528
                     /locus_tag="KRL22_003401"
     CDS             9981..11528
                     /locus_tag="KRL22_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH1273839.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVLVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            11862..12728
                     /locus_tag="KRL22_003402"
     CDS             11862..12728
                     /locus_tag="KRL22_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH1273840.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
BASE COUNT         4940 a         1335 c         2324 g         4146 t
ORIGIN      
        1 tatataataa aacaaaaaaa cactatatat attcgataaa ataaaattta aacatataat
       61 attttatgta tatattaata aaaggacata ttgtgttata atggtatcgt ataaaatcat
      121 ttacgggggt ggtattaaaa tgtttcaatt tgaaacacaa atacacaaat taagacatga
      181 tgttttaact gcaatagcta gacttggaaa agaagataac cttaccagag aagcaatgga
      241 taatattcag tatgaaataa taaagggtga gaaacctaca tacagatgct gtgtttataa
      301 agaaagagct ataatatctg aaagagtaaa tgtaagtatg gggttacaac caggtcaaga
      361 taagatagat ttagatacaa tggatataga agaagatgaa caaattatat atattttgga
      421 agctgcatgt gacagttgtc caataaatga atttacagta acagatattt gtagaggatg
      481 tctagcacat agatgtaaag aagcttgtaa atttggagct ataacacatg tcggaggaat
      541 ggcctatata aatcatgaat tatgtaaggc ttgtggaatg tgtaaaaaag cttgtcaata
      601 tgatgccatc tcagaggttg ttagaccatg taagagtgtt tgtccaacta atgccttagg
      661 atttgataga gaaaatatga aagctatgat acatgaggat aaatgtttaa actgtggagc
      721 atgtatgtca gcatgtccat ttggagcaat atctgataag agtttgatag ctcctgtagc
      781 tagaaagtta gttcaaaaag agaaaatgta tgcggtggta gctccagcta taacaggtca
      841 agttgaagca aatgttacat atggtcaaat aaaaaatgct ataaaatcac taggatttgt
      901 tgatgtatta gaagcagctt gtggagcaga tgcagttaca gttcatgaaa gcttagaatt
      961 tgctgaaaga atggaaaagg gagaagcttt tatgacaaat tcttgttgtc caggatttgt
     1021 tggttatata gaaaaaacat acccaaatca tgtaggaaaa atatcttcta cagtgtctcc
     1081 tatgatagct agtggtagat ttataaaaag tcatgaacca gatgctaaag ttgtattcat
     1141 aggaccatgt acagccaaaa agagtgaggc agctaagaaa gaattaaaag gagctgttga
     1201 ttatgtactt acttttgaag aaataatggc attatttgag gcatttgata tagacttggc
     1261 taagtgttca aatgaagata tagatgatgc atcaattttt ggaagaggtt ttggagctgc
     1321 tggtggtctt acaaaagcta tagaaaatta tcttgctgaa aaaggtattg gtgttaattt
     1381 tgaacctgta aagatttctg gttcaagaga aatcaagaaa actatgacta tggctaattt
     1441 aggaaagcta gaaggtaatt ttatagaagg aatgatgtgt gaaggtggtt gtataaatgg
     1501 ttctggtaaa ttcttatcag gtgcaaaggt taaagccact tttgatagaa aaaattctca
     1561 atcaactaag aaaagtgtct tagcaaatac aaagataaaa gattttagta atataaattt
     1621 agaaaaataa agataataca aagcaacaaa aatacatatt gttaatagag ttgttctaag
     1681 ttgaggttta acttttggac aactctattt ttatttatat atttaattat tgaacaacta
     1741 aaataaaaat tatatacact taaaataaaa attacatata taatattttg tatataactt
     1801 aacaaagtat atgcctatgt tataataatt tatagaaata aataaaaaat acaatataca
     1861 taatagtaga aatatagcaa aaaggtgtga tttataggga ggattactta tgtttgaatt
     1921 tgaaacgcaa ctaaaaaggt taaaacatga agttttaaca gcagtagcaa gactatctat
     1981 tgaagaaaat ttaacaaaag aaaatataga aaaaattcca tatgaaataa ttaaaggaga
     2041 aaaggcgaga tatagatgtt gtgtttataa agagagagaa gtagttcttg aaagggcgca
     2101 acttgcatta agtttaactc caaatagtaa atatggagat ataaatccag attcagttag
     2161 tttggacaca gatgagcaaa ttatatatat agttgaagca gcatgtgata gatgtccaat
     2221 aaatgaattt acagttacag agctttgtag agggtgtttg gctcatagat gtaaggaagc
     2281 atgtaaattt ggggcaattt cttatataaa tgggagagca tatataaatc atgatttatg
     2341 taaggcttgt ggaatgtgca aaagttcatg tcaatatgat gctatatcag aagttgtaag
     2401 accttgtaaa agcgtttgtc caacaggagc tttggatttt aatagaaaca ctatgaaagc
     2461 aatgatacat gaagataatt gtataaattg tggagcatgt atgtcagcat gtccatttgg
     2521 agcaatatct gataagagtt tgatagcacc tgttgcaaaa aaacttgcaa agaaagaaaa
     2581 tatgtatgca atagtagctc cagctataac aggtcaaata gatagtaata ttacatatgg
     2641 tcagttaaaa aatgctataa aatcactggg atttgtagat atgatagaag cttcttgtgg
     2701 agcagatgca gttacagttc atgaaagcaa tgaacttatt gaaagaataa aatcaggaga
     2761 taattacatg acaaattcat gttgtccggg attttttaag tatatagaga agatgttccc
     2821 agatgaaaaa gatagaatat catctacagt gtctcctatg gtagcaacag gaagattagt
     2881 aaaaaaaata gattctgatg ctaaagttgt atttataggt ccatgtacag ctaaaaagag
     2941 tgaggcaaca gagaaaagtt taaaagattc agtagattat gtacttactt ttgaagaact
     3001 aatggcatta tttgaagcat ttaatataga tttatcaaaa tgttcaaatg aagatataaa
     3061 tgatggttcg atttttggaa ggggatttgg agcatctggt ggacttgcca aatcagtaca
     3121 gaactatatt gctgaaaagg ggcttagttt tgattttgaa cctataaaag tatctggtcc
     3181 aagacaaatt aaaaagacaa tgacaatggc taaattggga agattagaag gtaattttat
     3241 agaaggaatg atgtgtgaag aaggttgtat taatggagca ggtaagtttt tatcaggtgt
     3301 aaaagctaaa aatacttttg atagaaaaaa tggacaatct actaaaaaga gtgttttatc
     3361 taatgataag attaaagaat ttgaagatgt aaatttagaa agataattgt tttggtacag
     3421 tcattttttt atcatgccac aaatatgcct aaaatttgcc ctttttatat gtgtatttta
     3481 cagagttaag gttgctatac tataaatatg taataaataa aatttatagg agcttttgga
     3541 tgaggaaaat agtattaaaa gatatcctgt ttttagttac tacattatct ataatagtaa
     3601 tattattgct tgtaacaaat ataactacta atagtaagat aaaatcaacg aatgaatctt
     3661 atttaaaaag tgacaaaaat gatgtgagtc aaaataatat tcagagtagc acaaaaaata
     3721 ctgcatttaa gactactata ttaagtactg gaaagtctga ctgtatattg gttgaaatag
     3781 gtaacaaagt cataatgatt gatacaggag aagataaaaa tggaaaacaa atagtggata
     3841 ggttaaaaga aaaaggaata aatacacttg actatttaat tttaactcat ttagataagg
     3901 accatatagg tggagtagat agtgtgttat ctagtgttaa agtaaagaat attatacaag
     3961 caaattataa gaaagatagt aagcaatatg atgaatatat tgattcactt aaaaaagctg
     4021 atatagaacc agtgctacta aaagataata tgaatattgt aatcaatagt gcagaaataa
     4081 acatacatcc ggcttcaaaa agcaagtacg agagttcaaa tgattattca ataatcacta
     4141 atataagcta tggagcacat aagtttttat ttgcaggaga tgcagaggaa gaaagattgt
     4201 cagagtttat aaatggaaat actttaaaat atgattttgt taaaatgcct catcatggaa
     4261 gatatgacaa attaactgaa acatttttag agtctatttc accccaatat gctgttatta
     4321 catgttcaga gaaaaaagaa ccagaggaag gtgttttaaa aatattggaa agattgaata
     4381 taaaaacatt tttgacttct aatggagagg tagttatcaa tagtgatggt aagacattga
     4441 gtgtgaatca ataatttttt taaaaatatc taaaaaaatt taaaaaaatc attagcaaat
     4501 attacccctt aaacatagta tattttagga gctgaaactc cacatacaaa atgactagga
     4561 ggtaacatat tatgttggat agattttttg gtgaaggcgg atttggtgga tgtgcttggt
     4621 ggataataat attattcttc ttattcttag cattccaaga ttgttgggct gaaatggact
     4681 tatgtgcatg gatacctttc ttaatattat tattaatact ttgtgaatgt ggtgacgttt
     4741 ttgatggagg atgtggatgc taaaaaaatc aatttagatg atttaataaa gcttatggtg
     4801 ggtataaata aaataccaaa ccaatcacaa tctagtgttt gaaggtagtc ggaaatcccc
     4861 cgctaccttc ttttttttat tgttaaaatt tatttttgaa ttatttcatt tacatataat
     4921 aatttttacg ataaagtctg atataattaa aaagaaaata aaatttattt ataggagatg
     4981 taaaaatggc tatagtggat aagattttca atgagataaa acttatggtt gcaagacttt
     5041 tattgggaaa aaaatacagt gaatatgaag aaaaagattt agtgtataat acagaagaag
     5101 aagttatact tataacttta aaaagattag tttttcaggg aaatgtaaac gaagcagaag
     5161 aaattttatt tgataaagct aagagtgtaa atagtgaaaa tatgcagtat atagcaatag
     5221 aattttatac tatgcttatg gaaaagactg atgaagaatt agaagctatg aatttttcta
     5281 aacaagaagt ttatcaaggt atagaagata ttagaaaagt attgaattta gaataaaaga
     5341 tatatgaaaa tattgaaata aattaatgct aaggtgagaa tattatactt atatataaaa
     5401 atataatatt cttattttat tagttatata ggtatatctt atttaccata aaactatctt
     5461 gaaaaaaatt aatcttaatt gtataatatt actttgagtg aaaaagtatt aacatttttt
     5521 tataagatgt tttactaaaa aaatatatat aaatatactg ttatcaacaa gaaatttaat
     5581 ttagtgaggt gttaagatga aagtaggatt tgaccacaaa aaatatttag aagagcagtc
     5641 taaatatatc ttagaaagag taaataattt tgacaaactt tatttagagt ttggaggaaa
     5701 attgatggga gaccttcatg caaaaagagt acttccagga tttgatgaaa atgcaaagat
     5761 aaaagtatta caacatatga aagaaaaagt tgaagttgta atttgtgtct atgcaggaga
     5821 tatagaaaga aacaaaataa gaggagactt tggtatcact tatgatatgg aagttttaag
     5881 attaatagat gatttaagag gttatgaact agatgtaaat agtgtagtaa ttactagatt
     5941 tgaaggacaa cctgctacaa ctgtatttat aaataaatta gaacgtagag gaattaaagt
     6001 ttataagcat tatccaacaa agggatatcc gtcagatgtt gagactatag ttagtgatga
     6061 gggatatgga gcaaatgaat atatagaaac tacaaagcca atagtagtag tcacagcacc
     6121 aggacctaat agtggaaaac ttggtacttg tctaagtcag ttgtatcatg aaaataaaag
     6181 aggtaatgta gttggatatt ctaagtttga gacattccca gtttggaatg tacctgtaaa
     6241 acatcctttg aatatagctt atgaagcagc tacagttgat ttaaaagatg tgaatatgat
     6301 agattcattc caccttgaaa cgtatggtga aatgtcagta aactacaata gagatttgga
     6361 attatttcca gtgcttaaaa aaataataga aaagataact ggaaaagaat caattttcca
     6421 atctccaact gatatgggtg ttaatagagt tggctttgga ataatagatg atgaagtaat
     6481 aagaaaagct tctatagaag aaataataag aagatacttt aaaactgcct gtgagtataa
     6541 aaagggacaa gttgataaag gtgcttatga tagaatgaaa atgattatgg aagagcttaa
     6601 cttaaagcca gaagatagaa atgttgtatt acctgctaga aactacagta ataaattgaa
     6661 agaaagtgcc gacaagaatg atacttgtcc tgtagttgca ttagaattag aagatggtac
     6721 aatattaact ggtaagggtt ctgatttaat gaatggaact gcagcagtag tattaaatgc
     6781 cattaaacat ttagccaata tatctgatga tatgcactta atatcacctg taatattaga
     6841 acctatcata aacttaaaaa caaagacttt agctagtaga aatgtttcac ttagttgcca
     6901 agaggtgtta actgcactta gtatttgtgc tgtaactaat ccaactgcac aatttgctat
     6961 ggaaaagtta gcattattaa aagggtgtca agctcattct actactatat taaatagaga
     7021 tgatgaacaa acatttagaa agcttggtat agatgtaact tgtgacccag aatatccttc
     7081 acaaaatctt tactatagtt aaaattatat aaaaaaatat gggctgtttt aaagtaatag
     7141 tttgagcagt ccattacaat tataataaaa tcagtaggct gtcttgtata agacagtctt
     7201 ttgtttttaa aacatcccat aaattaaata tatatactgt tatccataag gaattttaaa
     7261 tttagttcct tggaatacct attgtaaagc ttttatatag tttttgcaag tgtttttaag
     7321 gattttttat aaattatatt gaagttaatg gattatagat ggttttattt atggaaaata
     7381 tgaatatata aagaaaataa tgaaaaaata ccaaaaagaa acataagttt ggtataatta
     7441 aaaagtaata taaataaaat taatctattt atactttaaa aggtgataat aatgaaacat
     7501 tatagaaaaa taattcatat agatatggac gctttttatg catctataga acaaagagat
     7561 aataaaaaat taaaaggaag acctgttatt gtcggtggaa atccacaaag ccgaggtgtg
     7621 gttgcaacgt gttcttatga agctagaaaa tttggtatcc attcagctat gccatcagct
     7681 gtagcttaca ataggtgtcc atatgcagtt tttgtaagac ctcgatttga tgtttataag
     7741 agtgtgtcag agcaaataag agatatattt tatagataca cggatttagt tgaaccatta
     7801 tctttagatg aagcttactt agatgtaaca aaaaataaaa aaaatattga ttcatcaatt
     7861 gagatagcaa agcaaataaa aaaagatata tttagagaag ttggtcttac ttcttcagct
     7921 ggtgtgtcat acaataagtt tcttgctaag attgcatcag acttaagaaa gccaaatggg
     7981 ttaactgtaa taaccgaaga aaatgcccag gactttttag ataaattacc tgtgaataaa
     8041 ttttttggtg ttggaaaagt tacttcaaat actcttaaaa atttaggtat aaaaactgga
     8101 tatgatttaa ggtgtttaaa tttatttgaa cttgaaaata tattcaaaaa aagaggttat
     8161 gaattatata aatttgctag aggaatagac gatagaccag tggaaccaaa tagggttaga
     8221 aaatctgttg gggctgagac tacattaagt cataatttgg atattgatga agaagaaaca
     8281 cgcaacattc ttgatgaact ttgtgaagaa gtatgtcata gattaaaaaa ctctgagaag
     8341 tttggaaaaa cattaacatt aaaaattaaa tatgaggact ttacaaagat aactagaagc
     8401 cttagtttag aacactatat tgacgaatat aatgatataa gaagtggtgt agataatttg
     8461 ttgagaaatg ttgaggttaa tggaaaacaa attaggctat tgggagttac aatatcaaac
     8521 ctaagtgata aaaaagaaac ttataaagat attacattat ttgaatacat ggatagtatc
     8581 caaatgtgag ttttgtttaa atgaaataac actagcttta atactatata attgaggcta
     8641 gtgttatttt atgaatattt ttatattttt tgttttttga cattatatat tatatactat
     8701 atataaatac tttatatttg tagcaatatt cagacaaata gtgacctaaa aatcgtactt
     8761 tgtttacata aataaaatag tatgatataa ttataaaaac aacttataat attgaagaag
     8821 gttgcttgtt cgaaaaaggg gatgataaat tatgatagag ataagaaatg taacaaaaaa
     8881 aataggaaat aatgttatat tagatgatat ttctctagtt gtagaaacag gtacattggt
     8941 agttttgatt ggttcaagtg gttgtggaaa gactactact ttgaagctta taaacaaatt
     9001 aataaaacct acatctggtg agatatatat taatggcaaa ccaatttctc aggaaaatga
     9061 aatagagctt agaagaaaaa taggatatgt tatacagaac acaggcctat tccctcatct
     9121 tacaataaaa gaaaatatag agctaattcc acgcctaaaa aaggaaaaat ccgttgaaga
     9181 aattgaaaaa agaacgttgc aactacttga gatggtagga cttgatagtg atgaattttt
     9241 gaataagtat ccttcagaac ttagtggtgg acagcaacaa agaatcggtg ttgcaagagc
     9301 cattgctact gatgctgaaa taatattgat ggatgagcct tttagtgctt tagacccaat
     9361 aacgagaaca tctttacaag aacaattatt ttctcttcaa gatgaattga aaaaaactat
     9421 aatatttgta actcatgata tggatgaggc tttaaagata gctgataaaa tttgtattat
     9481 gaaggatgga agaatagcac aatatgatac tcccgaaaat atacttagaa agcctgcaaa
     9541 tgactttgta aaagatttta tcggagaaga tagagtttgg gataatccag aatatataaa
     9601 agcaagagat attatgataa aaaatcctat tgctgttaat tctactagaa ctgtaactca
     9661 aggaatagaa attatgagaa cgagtaaggt tgatagctta ctaattatag atagagcaaa
     9721 aacattaaaa ggtattgtta ctgtaaaaga tatgaaagat attgatgata agtcaatatt
     9781 acttgctgat attatgtcaa gtgagccttt gcatgtaaat gaaggtgata atttagtaga
     9841 aatactaaat gtaatgaatc gtaattcggt tggatatatt ccggttattt ctgatgaaaa
     9901 taaactggta gggcttatta ctagaagtag tttactttct gttttaagtg aacaattctt
     9961 agaaatggag gtgagtgttc ttggctaatt tttttaactt tatactatta caaaaagata
    10021 agattataga gcttttaata caacatatga gtctaactgt tacatctatt ttaatagcta
    10081 taatagttgg tgttcctctt ggaataatta tttcaagaat ctcatctctt agaaagtttg
    10141 tacttggatt tgtaaactta gtccaagcag ttccgtctat ggcacttttg ggtcttcttg
    10201 tacctatact tggtatagga agtaaaccag ccatatttat ggtagtggtt tattcattac
    10261 taccaattgt aaaaaatacg tatataggta taacaagtat tgacccagta gtattagaat
    10321 cagctaaagg tattggtctt acaagaaatc agacattatt taaaatacaa tttcctttag
    10381 cgcttcctat aataatgggt ggagttagaa tatctgcagt tacagctgtt ggtttgatga
    10441 ctcttgcagc atttataggt gctggtggtt tgggatattt agtattttca ggggttcaaa
    10501 ctgtaaataa taatatgatt ttagcagggg caatcccatc atgtataatt gcactgttag
    10561 ttgattattt atttagtaaa attgaagttg cagttactcc aaaaggatta aatccaaaag
    10621 cacctaagaa gaattatata gcacttaaag taatatctgt agtgcttgtt gtttcaatgt
    10681 tgttcgttgt ttttagttct agtttttcaa gtaaaaaaga tacaataact attggttcta
    10741 aagattatac agaacaactt atacttggta atgtttatgc tgaattagta gaaaaaaata
    10801 cgaatcttaa agttaagaag aatttaaatc taggtggttc atctgttgcg tttaatgcaa
    10861 ttaaatctgg tgagttagac atgtatgttg actatacagg tacacttttg gtaaatgtaa
    10921 tgaaacatgc tccgattaaa gatgctgatg aagcatataa tgttgtaaaa gatactatgg
    10981 aaaaagaaaa tcagttaact ttacttgacc ctcttggatt taataatact tacacattag
    11041 ctatgatgcc tgaaactgct gaaaagtatg gaataaatac tatttctgat ttgactaaat
    11101 atggtaaaga atttacattc tcaccaactt tggagtttga aaatagagaa gatggtcttg
    11161 tagggctttc tagagattat ggtttaaaat tcaaagatgt aaaagcaatg aatggaagtt
    11221 taagatatac agctttagat aataatgaat ctcaggttat agatgcattt ttaactgatg
    11281 gtcttattaa aaagtttaat cttaagatat tagaggacga taaaaatttc tttgtaccat
    11341 attatgcagc accattagta agagaagata ctttgaagaa atatcctgag ttagaaaaag
    11401 ttatgaatat gctttcagga aaaataaatg aagaaactat gagagaactt aactatcaag
    11461 tggatgaact tggtaaatca ccagaagaag ttgctcattc attcttagtt aaagaaggct
    11521 tagtataaaa aattaatagt ttatatcaaa aatttaaggg agtgtctcaa aatgaacttt
    11581 ttagttcatg aggcactctt ttttatatga aatcaaatat attttatcat ttcaacaata
    11641 aaaaagaaga ttatctttat tttgagacag tctcttattt ttatgtatac caaaaccata
    11701 cctacgattt ttatttataa ttaagtttca aatagaatga acaagtacaa ccaattttga
    11761 atataaatat agtaaatgtg cttatatacg attttattgt ctggttgatt gatattgata
    11821 gatagctttc tttattgaat cgaagggagg gggaatttgt tatggataac tataagaaag
    11881 tgaagcaagt attgtggata attttatttg ctaattttgc agtagcatta ttaaaaatca
    11941 ttattggtaa tcaaataaaa agctatagta tgacagcaga cggatttcat tctttgtcag
    12001 atggagcatc taatatagtg gggcttatag gtattttctt tgcatctaaa ccaaaagata
    12061 aaaatcatcc ttatggacat aaaaagtttg aaattataac cagtttattt ataagtggta
    12121 tgttgtttgt tatagcaatt aagataattc ttagtgcagt gttaagaata gctaatccag
    12181 ttgtacctgc tataactata gaaagtttaa ttgctttaat tattacactt tttataaata
    12241 tttttgtatg catgtatgaa tatagaattg ggactaaact aaatagttat gttttgattt
    12301 cggattcatt gcatacaaga agtgatatat ttgtgtctct aggtgtattg gttactttag
    12361 ttggtgttaa gttaggattt ccagtaataa tagaatctat agttcctatt attatttctg
    12421 cattcataat ttattcggct tatggaatat ttaggccatc tattggaatt ttggtcgata
    12481 gagtggctgt agatgaggat tatataaaag aaattgtgtt tgaatttaat gaggtaaggg
    12541 atgttcacaa tatcagaagt agaggtagca aaagttctat ttatattgac atgcatgtaa
    12601 tggtagaccc atttataagc gtagagcaat ctcatgattt aacacataaa attgagaaac
    12661 aaatacaaga agaaattaat gaaaatgctc aagtaatagt ccatattgaa cctttttata
    12721 gtttttaact tagttataaa ataca
//
LOCUS       DAEPUT010000110        12568 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.113, whole genome shotgun sequence.
ACCESSION   DAEPUT010000110 DAEPUT010000000
VERSION     DAEPUT010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12568
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.113"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            133..1014
                     /locus_tag="KRL22_003403"
     CDS             133..1014
                     /locus_tag="KRL22_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH1273841.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(1075..2283)
                     /locus_tag="KRL22_003404"
     CDS             complement(1075..2283)
                     /locus_tag="KRL22_003404"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBH1273842.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(2356..2608)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(2760..3749)
                     /locus_tag="KRL22_003405"
     CDS             complement(2760..3749)
                     /locus_tag="KRL22_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HBH1273843.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVIGLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            3901..4341
                     /locus_tag="KRL22_003406"
     CDS             3901..4341
                     /locus_tag="KRL22_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1273844.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            4668..4895
                     /locus_tag="KRL22_003407"
     CDS             4668..4895
                     /locus_tag="KRL22_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1273845.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            4921..7041
                     /gene="feoB"
                     /locus_tag="KRL22_003408"
     CDS             4921..7041
                     /gene="feoB"
                     /locus_tag="KRL22_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH1273846.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIYAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(7174..7992)
                     /locus_tag="KRL22_003409"
     CDS             complement(7174..7992)
                     /locus_tag="KRL22_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1273847.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            8199..8483
                     /locus_tag="KRL22_003410"
     CDS             8199..8483
                     /locus_tag="KRL22_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273848.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYPYLIELEYIEMSLLIRRLDTAITSLALVSIIIIASYYLIRKNV"
     repeat_region   8583..9406
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=8720..8747
                     /rpt_unit_seq="tttacattccatatagttaatataaaac"
     gene            complement(10065..12158)
                     /locus_tag="KRL22_003411"
     CDS             complement(10065..12158)
                     /locus_tag="KRL22_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1273849.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPEEIVENPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVEIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         4489 a         1820 c         1496 g         4763 t
ORIGIN      
        1 tgcaaataat gtcatataag ttacacttta gttatcttag ttacaacttt gtcggtttac
       61 tttttctact ttcttcgata taattataat atatttttga tacaattcga caaaaggggg
      121 aatgctgtaa ttatggtaaa aaaaagaaaa aagaaaactg ttacacttac tatacttgtt
      181 gtaatagtta ttggtatttt ttctatggca tgggcggaca tgtctagaaa aaaagaaatg
      241 aaagaaactc aagaaagact taaagctgaa agattagaaa aagaaagaat tgaaaaagaa
      301 aaaaatgaac ctattattgg tgcaaaaaaa gaagctgtaa aagaatatgg atatgacgca
      361 aaaatagttt gggacaaact taacaaatac gactattcaa acaatggaga aaagatagtc
      421 tttcttacat ttgatgatgg accatctact actaatactc cacaagttct agatatcttg
      481 aaaagacatg gtgttagagg aactttcttt attaagggtg attctcttga aagaaaagga
      541 gctaatgaaa ttttaaaaag aacatttgac gaaggaaatg caatagccca tcactcttat
      601 actcatgact ataaaaaact atatcctaac agaagcctaa atctcgatac attcgtaaat
      661 gaacttaaca aaactgatga agctatgaaa aaagtcttag gaaagaattt ttcctcaaat
      721 gtagttagat gcccaggcgg gtatatgtca tggaaaaata tggaacctct aggaaactac
      781 ttaaaagaga aaaacatggc atcaattgat tggaacgctt taaatgctga tgcagaaggt
      841 aaaaagaaaa atgcacaaga attatttgaa catgcaaaga aatcttctga aggcaaagaa
      901 atggttgttc ttttaatgca tgatacttat ggaaaacaag aaacagtaaa tgcattggac
      961 caaattataa catattttaa agacaatggt tatcaattta aaattttaat ataataaaaa
     1021 agcaagttta ttgaatgtac attttatact caatagactt gcttttactt tactctattt
     1081 tactagctcg atttttacaa attttttctt tcctatttga acaactaatt cactctcttt
     1141 tacaatagtg cttaaatcct ctactttttc accatttacc tttactccac cttgagaagc
     1201 taatcttcta acttcactct tactcttaac aatctcatta gaaactagta cttcgattaa
     1261 gtcaaatcca tcttccttaa cttgaattgt ttgtatatct tcaggtattt gacctttttg
     1321 gaatacagat ttaaatcttt cttcagcttc tttagcagat tcttctccat ggtataatgt
     1381 tactatttct cttgctaagt tcatctttat atctcttgga tttactgaac cctctttcaa
     1441 ctgagattct attttattaa cttcatcagg atgaacatct gtcactaaat tgtagtattt
     1501 aattataagt tcatcaggaa tttccataga tttttggtac attattcccg cttcttcatc
     1561 tattccaata tagttaccta aactcttact cattttttct ttaccatcta atccttctat
     1621 taaaggcatc attattacta tttgagactc cataccaaat tctctttgta atgatcttcc
     1681 cattagtaaa ttgaatcttt ggtcagttcc accaagttct atatcagctt ctaatgctat
     1741 agagtcatat gcttgcatta atgggtagaa gaactcatgt actgatattg gcatttgtcc
     1801 ttcatatctc tttttaaaat cttctctttc taacattctc gcaacagtaa tagttgctgc
     1861 taattttatt acatcttcaa aatttaactt agctaaccac tcgctattaa atcttacaat
     1921 agttttttct ttatctaaaa ctttgaaaat ttgttcttca taagtttttg catttgcaag
     1981 aacttgctct gttgttaaag cttttctagc tttagatttt ccagttgggt ctccaatttt
     2041 tcctgtaaaa tctccaatta ttattactat ttgatgacct aaatcttgta attgtttcat
     2101 ctttctaaga actactgtat gccctaaatg tatatctgga gcacttgggt ctagacccaa
     2161 ttttactatc ataggttttc cttctttttc tgatttaata agcttttccc ttaactcttt
     2221 ctcatctatt aaatcatcta cacctttcat aattattcgc atttgctcgt ctatcgattt
     2281 catttttcat tcctcctaaa atatttatat aatctataat ttttattttt ataataaaaa
     2341 aagctttcat cctcttaaaa ggacgaaagc attgcttacg tgttaccacc ttagttcatc
     2401 aatatctcac gatattaatc tcttagagta caattacata tactcgtgta ctataacgtg
     2461 tactaatccg atatctctta atggttgtta tctttcagag atagtgctct gagatgtatt
     2521 caaactaaat caatttattc catttcacca aactggaact ctctgttaaa taaaatatag
     2581 ccctacttct tctcttcata gcatttatat attcagatta tttcatcaat tacaagaaat
     2641 ttttcttaac ttactcataa tatattatta tttttatatt ttgtcaacct tttttattat
     2701 tatatacatg tttttttaca ttatactact tttttatatt ttttaccaat acccaaaatt
     2761 tatttttcaa tcaaaagatt tatttgttta ttgactatat tactctgact caatcttata
     2821 tttattttct tatttaaaaa tgcgtttata attattaaac caataactgt tacatcaaat
     2881 ataaaaaaca gcaataaaat tattatcaaa aataaaattc tagcatataa taattttcta
     2941 aacttagcta ttataaagtt ttgtagtgac atacatgagt ctctaatgat aaaatagaca
     3001 cttatatagg ttattgatat aaagattgtt tttaaataaa cagaatcaac tttaacattc
     3061 aacagtttta gaacttcaaa aatggctaga taagaaacac atatgtaaaa agcttttttt
     3121 gagcaacata aaaattggtt taaatttcta aaattcttaa atattaaaaa tttttttaaa
     3181 gaattagaat ctaaaatatg caatttattc cctaaaatta aacttaataa atatatgcaa
     3241 aacaccatac caaaaggaaa caatgctatc attaaataat aaataaaatt tgtataccca
     3301 ttaaaataaa tccatttgct atatccttga aattctttca taaaactata acctattaat
     3361 gttgaagcat atatatcaat gaaaaccatt acaataaccc caaatactga accatatact
     3421 aaatcatcca taaccattgt aggcttattt attagatagc cacacattat accaagtaat
     3481 acactctgac ttgcccaaat agcagttcct agatttccaa gtaccagaga aattattaaa
     3541 agcgaagtaa ttccagataa aatggtatac tttaaatcac atttcaagca gattatacaa
     3601 aaaaatactg gcactataaa atctaagtaa atagcatatc caaatccagt actcacagct
     3661 ataattgtta ctactatgaa taaagatgac aataaagctg cttcagttaa ttttttagta
     3721 gtattcaaaa cactgcctcc ataaatcata aattttctaa ctaaagtttt gtttttaata
     3781 tagtatatca ctttttaaaa atatttttaa taaatataaa ttttaataaa ggtatttatg
     3841 ttaaaaatgg tataatgtat cttaatattc agttttttaa gatgctagga ggtaattact
     3901 atgtttaaaa ttaaacactt taatgatttg agtttagatg aattttatga aatagcaaaa
     3961 tcaagatatg aggtatttgc ttgtgaacag aagatatttt cattaaacga ttatgatgat
     4021 atagataaaa gctcttatca catattttta aaagaaaatg gattgatttg tgcttacgct
     4081 agaataattc ctaaagaata cagctcttat aatgatgttt ccattggtag agttttagtt
     4141 ctttctagtc atagaagaaa aggattagca aaacaaatga tggattgtgc tatagatttt
     4201 ataaaagtta acttacacga aaataatata accttatcag cacaaactta tataaagaac
     4261 ctttacttat cttgtggttt taaagaaatc tcagaagtat acgacgaagc aggtattgaa
     4321 catattaaaa tgagattata gtgttgacaa gctaatattg ttaatatata atttaagtat
     4381 aaattaaata ttgaattgat atttaggtat ttgaaaatac cttacataga gtcagaaggc
     4441 ttttgctttc tgactttttt attatcaaaa ttcaataatt atatggattc aaagtgttaa
     4501 tttttattct atattctact ttccccaaaa gtaagaatta tacccaactt tgtatgatag
     4561 gcatcttgcc tatctttttt ttgtaaaagt aacaaggtaa taatataatg catagtttaa
     4621 aataagaaga ttagcccagg ctaaatttca agcatggagg tgctattatg aaaaacctta
     4681 acgatattca agtgaaaaaa actgtcaaag ttgaagatat attatctagt ggtaatttaa
     4741 gagaaagaat gttagcgctt ggtcttacta gaggagctgt tatagatgta gttagaaaag
     4801 gtccaaaaaa taatttaact gtctataaaa tcagaggtag caagatagct ctacgacaag
     4861 aagaaagtag cttaatatta gtttctgaca tttaaaaatt tctagcagga ggatattaat
     4921 atggggttga cacataactc aactaaaatg agttctttaa aagacatgtt tgatatagac
     4981 aataaggaag accagtttgt aattgcattg gctggcaatc caaatacagg taaaagtact
     5041 gtatttaatc atcttacagg acttagacag catactggaa actggccagg aaaaactgta
     5101 gctacagctc gtggtaattt taaatataaa aataccgaat atgcattaat agatttacca
     5161 ggaacatatt ctttatttgc cttatcacaa gaagaaattg tagctcgtga ttttatatgt
     5221 tttggtaatc cagatgcagt aatagtagta tgtgatgcta catgtcttga aagaaattta
     5281 aatttagtat ttcaagtgat ggaacttaca gataaagtta ttttgtgtat taatttaata
     5341 gatgaagcta gaaaaaaagg cattactatt gataaaaaac ttttagagga ttctcttggt
     5401 attccagtta ttttaactgc tgcaagaaat ggctctggta tggatgaact attggatact
     5461 ttaaatgatg tatcttttga caaatacaaa ttaaataata aacctgttag atacaatgaa
     5521 aatatagaga atgtggtaaa atcaattcaa ccagaattgg ataatattat accaggtata
     5581 aattctagat ggttgggact tagacttatt gatggcgatg aaagtatatt tgaatctatg
     5641 agtaattata tagacaaaga ttctatatat gctattaatg aagtaaagaa aaagattcca
     5701 gacaatataa ataaacagaa aataagagat gagtttacta aaatcaacta tgattatgct
     5761 aaaaaactga gtgatgagtg ttgttctaat gttgctaaaa aatcaactga tagagaagaa
     5821 aaagtagata aaatattaac atctaaaata tttgggcttc caataatgct cttattatta
     5881 ggtactatat tgtggattac tatagaagga gctaactatc catccacttt attatctaat
     5941 ttattactcg gatttgagcc aagtatttcg ggtatattaa atagtattaa ttgtccatca
     6001 tggttaaatg atatgttggt tttaggatta tacagaacat tagcatgggt aatctctgta
     6061 atgctacctc ctatggcaat attttttcca ttatttaccc tacttgagga ttttggatat
     6121 ttgccaagag ttgcatttaa cttagaccac ctatttaaaa aagcttgtgc acatggaaaa
     6181 cagtgtttga ctatgtgtat gggatttgga tgtaatgcag ctggagttat tggttgtagg
     6241 ataattgact ctccaaggga aagacttata gctatactta caaacaactt tgttccttgt
     6301 aatggtcgtt ttcctacttt gatagctata tctacaatat tttttagctc agttataacc
     6361 aactctttcg tatcaagcgt agcaactgca ctttgcataa ctttactgat aattctaggt
     6421 gttataataa cattgttggt ttcttatact ctttctaaaa cgctattaaa aggagttccg
     6481 tctacattta cattagaact tcctccttat agagttcctc aaataggaag aactttatat
     6541 acctctataa tagatagaac aatatttgtt ttaggaaggg ctgtaatggt agccatacct
     6601 gctggtgtca taacttggat atttgcaaat atatatatag gagatttaag tatattatca
     6661 catgttgcaa actttttaga ccctttagct aaattaattg gtcttgatgg ttttatatta
     6721 cttgctttta ttcttggatt cccagcaaat gagatagttg tacctatact tttaatggct
     6781 tacctagcaa ctggttctat gatagaatta gatagcttta gtgctttagg tcaagttctt
     6841 agagaacatg gatggactta tttgacagct ttaaatgtta tgctgttcag tttactgcat
     6901 tggccttgtg caacaacact tttaacaata aaaaaagaaa ctggtagttt aaaatggact
     6961 gccttaggat tcttaatgcc tactatactt gcttttgttg tttgtttttt aacaactaca
     7021 gtttacaatt tatttatata attagtatta actgacagta gacatatatt agagaaacca
     7081 tttaaaaatt tatatacttt attataaagc atagagatat attcaatgat aagtaaaatt
     7141 acttaacatt tgaatatatc tctattttaa ttcttatctg gatacttgga ttgaaatttc
     7201 agtcatataa ttatcttcat tactttcaca aaaaaagtca agtatactct cctcatacga
     7261 atttccaaca attttatatt cattttcata tatatatttt ttcaattttt cgtaagattt
     7321 atatgaatcc tcatattttc caatatgttt tatgcaagca tacattcctt ctggctttac
     7381 atatagcttt ttatccttta tttttttatc tatcttcaaa taaaaacttg atatacttaa
     7441 atagtcccca ttttttatat tttcattact tactattact cccaactcat atccttgata
     7501 caaatttttc gatttacaat aattggtaaa atctattaat tccatcataa aatcactatt
     7561 actcatatta ctcaaatcac ttgatagaac taaatattct tcaaactttt tggatatata
     7621 aatttcttca ctattcattt tagaaattcc ttcaactgtt atatttattc tattttgcat
     7681 cttagaactt atctttctta gtttttttat tttttctctt atcttttttt cttcttcttt
     7741 aagcattttc acacaaagct ggggagttct attttgtata tactctttta tttcctctaa
     7801 actcattcct atttctctta atgattgtaa tatatcaagt gtatcatatt gataaactga
     7861 gtaatatcta taattatttt tatctttata ttcaggagaa aaaataccta ttttgtcata
     7921 gaaaattaat gtctgcttag atataccaca caatttagca aattcacctg ttgtaaaata
     7981 ctgtttttcc aagggttata cactcctttt ctttttgttg tctatatagt tactatattc
     8041 tttattattt actaaatcaa atagttatta ttttagaaaa tcaatatggt tttgatttta
     8101 aagcttaaat gtcagttaga tgtcagttat aaatatttta cccattccca tcataaaaaa
     8161 gatatcccct cttaactttt ggatggaata ttatatttat acttgttaga gtgaaaattg
     8221 taataggtgc tacaataaga tatttaatta aacataaagt taattattgt aataaaaaat
     8281 ctttagataa attagagtta aagtatggaa atatagatag agaaaaagct gttaaactag
     8341 aaatatttta tccgtattta atagaacttg aatatataga aatgagttta ttaataagaa
     8401 gattagatac tgcaataaca tcattagcat tagtatctat tataataata gcatcatatt
     8461 atttaatcag aaaaaatgtg taattatgta agctatttat aataaaacac tgataaaatt
     8521 aataataaaa aggtaatagg atttctatac tacctttttg tttttataat atagtgtaat
     8581 tttattatat ttttgtatgc taatataact agataatcat aagataacac attaaaagaa
     8641 aattataaaa acttacattc tgtatagtta atataaaaca taagtaatat aaatttatgt
     8701 aaagcaataa aagatggatt tacattccat atagttaata taaaacgatt tcaaatgatt
     8761 agaataaaaa tatcagaatt gctatttata ttccatatag ttaatataaa actttaaatc
     8821 atctttatga acttcaaaag taggaagcgt atttacattc tatatagtta atataaaact
     8881 agtaaaatca aactatgaaa gaataaatgt ttttaatatt tacattccat atagttaata
     8941 taaaacatca atactttgat gcagttttta actagttttt caatttacat tccatatagt
     9001 taatataaaa ctgataagat tcttgttact gctgttcgaa agttcaaatt tacattccat
     9061 atagttaata taaaacgttt gaggatttat tagcaactca tagtgaaaag tatatttaca
     9121 ttccatatag ttaatataaa acatggtgtc aaaaggctat attaacacct aggtacaaaa
     9181 tttacattcc atatagttaa tataaaactt agtgtttgtg ataatttcag tttcttttaa
     9241 aaattcttta cattccatat agttaatata aaactagttt taataaaaac gaatctttta
     9301 tttgcaagca catttacatt ccatatagtt aatataaaac gaggtggttg gtatggtgga
     9361 ggaagcggtc caaccggatt tacattccat atagttaata taaaacacca aaataaactt
     9421 agtattttca acacttacac gtatacaact ctcttaaatt tgcagtgaac gagcaatagt
     9481 gcaattgata acgcttatca tgcactctca acgccttata tttcaactgt tacgccaaat
     9541 tttttcacaa atatcgctca ctgcaaaatt tctataattt tattatatca taaatatatt
     9601 acttttgaat attgatacca atttatacca taataaaagc aaaaaaacgt aatctatcta
     9661 cattagattt aaattctata acttaaagtt ttttacataa tatttatgct tgtttaatca
     9721 atctaatata tcatttttgt atattgcttt taatggtctt ttttcttaaa taaatatcta
     9781 tctgaacaag catagtttaa ttaaaaactt ttgtattccc ttaaaactgt atctacctct
     9841 tattatttta tttatgatat attattttta atctaaaaat agatatctat ttttattatg
     9901 gttatccctt tttaaaatac tttaatcata tactattccc aatttaacat ccattgaaat
     9961 gctattttct tatattgcaa tttataattg atatatcttc aatataataa tttaatgtat
    10021 ttttgatttt aaagcttttc agtaatatta ttgataaatt agaattaatt atctagcttt
    10081 aaaaggtcaa agatttctgt tgctgtctgc ggttttccaa ataaatatcc ttgtatgtaa
    10141 tctggcttta tttgtttaac taaatcatac tcttcttgtg tttctacacc ttctaaacat
    10201 acttttattt ctacgtcatg acaaattgca acaataaaat gtataaatgt agcatcaaac
    10261 ttactcttta atatatcttt aacaaatact ctatcaattt tcactatatc tattggagaa
    10321 aattttaaaa cttctagaga cgagtatccc gtaccaaaat catccatagc aatataaatt
    10381 cctaaatctt gtaaagcctt aaatttaaac tgtaaaatac tcatattttg tactgtatga
    10441 ctttctgtca attctaaaac aagattttga taaggaaaat tttcatcatc tataattttt
    10501 actatatctt caataaatgt gtcttctaat atttgaacag ctgaaacgtt tacactcact
    10561 ttaaaaaaag gatagtaatc aatccatttc ctaaaagtac gtaatgccat tcgaagcacc
    10621 caagccccta caatatttat catatcattt tcttctaata ttggaataaa ttccaaagga
    10681 gaaattgctt tgcatttgtc attagtccac cttaaaagaa cttctacacc tattatttta
    10741 tgactttctg tatctacttg tggctggaat cgaagactaa accccctaaa atcatcatta
    10801 attgatgcct ttaaatcccg catcatttct aatgaataca ttttattttt taatatttct
    10861 tgggagaaaa aaacaagcct gtttttacca tgctctttcg catattgtaa agagtaacta
    10921 gcacacttat aaagttcttt tactgtatct ccatgttttg gatatattac acaaccagca
    10981 gaaattgtta tatttaatcc atattttctc catagttgaa ggtgtataat catattctgt
    11041 atttgattat atagagttag aatttcattt tcttcaacat tatcaacaag aatgcccatt
    11101 tcgtccccat caagtttata aagttcagca ttatctggta aaatagattg tatagactgt
    11161 gctagtgttt ttattatatt atctccaaaa tccctatcat acatctcatt aacattttta
    11221 aaatcgtcaa tatctaataa tactatgcat aatttttcaa tcataggatt tgaaatttta
    11281 tcttcaaata cactcataaa ttcatgataa ttcagtaact gtgtcaatga atcaatctta
    11341 ttttgtttac ctaattgcgt cattattcct gcaaaaatac ttggttctcc aaattcatca
    11401 cgcattagtt gacctctaca tcttaaccat atatattctc cactacgatt tttagcccta
    11461 aattccactg tatggtaatc catctggttt ttacctattt cagtgtttga cttataaaag
    11521 cgattccagt cttctggatg tacaattttt ttccagtaaa caagcggatt ttcaacaatt
    11581 tcttctggta agtcaaataa ttcaacttgt gatggtgaat atcgaaatac gcctgttttc
    11641 atattgcaaa tgtatatata ttcatctgta cctctaatca aagcatcata aagcaatgta
    11701 gaattataat caaaattgtc tcttgaaaaa ttaaaaactc ctttttcttc tttattattt
    11761 gatatttcat gaaattcatt aatcttaatt ggtttattta agcttgttga gtttgcaata
    11821 tctattgatt gatgcatatg aacaactgtg ccatcttgcc atgtaattaa actatcataa
    11881 ttttcaaaaa cacgatttaa cttattacat ttttcatacc actttattaa tactcctttt
    11941 ttatcattct ttaataattc taaaacttta caaaaactac aagtagaatt tttttcagga
    12001 tataatactt gccaacaaac ttttccttct ggatctaaaa tattatattc ttctttcatt
    12061 tttttgttca taaaaataat ttcattagta tgaatatttg taacatatat attaatctgt
    12121 agttgattta atataacttc aaaattatgt ttgttcatat acttatctcc tccatagtta
    12181 ctgctcttta taacaacatt gttaaaatta ttctttttag aagatttact tataacttat
    12241 acatatacac taaatacctt aatttaatta gaaagtttat tacttcatat tttaaattat
    12301 aattgataaa aaaaaataca gcaatatagt attaccaatt taaaaaaaat taatattaca
    12361 taatacatct ctctcttata ttaaatttta acttggtact aatcttgaca aattgtccac
    12421 aaaaataaat tatagatttt attattgttt taaattttta taaaaaatca gtattattga
    12481 tactattgaa gttaaaaagc attaatttct aaaaacatca taatttttct aatagactta
    12541 atcactttta atatatatag taaaacaa
//
LOCUS       DAEPUT010000111        12282 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.114, whole genome shotgun sequence.
ACCESSION   DAEPUT010000111 DAEPUT010000000
VERSION     DAEPUT010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12282
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.114"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            235..417
                     /locus_tag="KRL22_003412"
     CDS             235..417
                     /locus_tag="KRL22_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273850.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            1249..2163
                     /locus_tag="KRL22_003413"
     CDS             1249..2163
                     /locus_tag="KRL22_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HBH1273851.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            2553..3200
                     /locus_tag="KRL22_003414"
     CDS             2553..3200
                     /locus_tag="KRL22_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH1273852.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMSVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(3367..3936)
                     /locus_tag="KRL22_003415"
     CDS             complement(3367..3936)
                     /locus_tag="KRL22_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1273853.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(3941..4840)
                     /locus_tag="KRL22_003416"
     CDS             complement(3941..4840)
                     /locus_tag="KRL22_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1273854.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLNILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(4851..5000)
                     /locus_tag="KRL22_003417"
     CDS             complement(4851..5000)
                     /locus_tag="KRL22_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273855.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(4993..5577)
                     /locus_tag="KRL22_003418"
     CDS             complement(4993..5577)
                     /locus_tag="KRL22_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBH1273856.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            5966..7291
                     /gene="cdeA"
                     /locus_tag="KRL22_003419"
     CDS             5966..7291
                     /gene="cdeA"
                     /locus_tag="KRL22_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HBH1273857.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIFALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(7386..8180)
                     /locus_tag="KRL22_003420"
     CDS             complement(7386..8180)
                     /locus_tag="KRL22_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273858.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMIIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(8181..9056)
                     /locus_tag="KRL22_003421"
     CDS             complement(8181..9056)
                     /locus_tag="KRL22_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273859.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEKELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIVLNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSESDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(9060..9428)
                     /locus_tag="KRL22_003422"
     CDS             complement(9060..9428)
                     /locus_tag="KRL22_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1273860.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(9610..10269)
                     /gene="deoC"
                     /locus_tag="KRL22_003423"
     CDS             complement(9610..10269)
                     /gene="deoC"
                     /locus_tag="KRL22_003423"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBH1273861.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(10305..11492)
                     /gene="murJ"
                     /locus_tag="KRL22_003424"
     CDS             complement(10305..11492)
                     /gene="murJ"
                     /locus_tag="KRL22_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH1273862.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTVFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMIIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(11569..>12282)
                     /locus_tag="KRL22_003425"
     CDS             complement(11569..>12282)
                     /locus_tag="KRL22_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1273863.1"
                     /translation="VKVRDKQVPKGRILNATISKEPSDRYYVSLCCTDVDIEAFENTN
                     NQIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLKV
                     ARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFI
                     RQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDI
                     NASINILKEGLRLITIQNK"
BASE COUNT         4270 a         1891 c         1374 g         4747 t
ORIGIN      
        1 tattaattta tattaaatat ctactaactc aaatattcat aattaaactt taaactggat
       61 aaattttctt ttaagaatga aagtttatcc agttttgcga ttataataac cagttttaca
      121 tatccacttg taaaatatat ctaagcaata tatcatacta tatagattta tgagtgaaat
      181 aatatctgct atttactgaa tatttttatt tttcgttttt tagggggatt agttgtgttt
      241 aaagataaga ttgatgaatg tgttcatata atgactgcat atattgctag tttaaaagaa
      301 tactattcat tcatagaaac tcaaattggt gattttatta aaaaatatgg agaagatgtt
      361 gtagagttat gtctccatag agtgatgatt ctactatgcg aatgtggttt ggcataaaat
      421 taaatttatt aaaatgggta agaagaatcc tatataatat tcttcttacc cattttaata
      481 tatcaatttc atagcttatc gtttaaaata ttttacatcc attactagac aactttacat
      541 tctcttttta attctagtat atttaaatca ttttagttgc tccttattta ttcttattac
      601 ttgttttatt ttataaataa aataattctt tttaataatg ttttttgttg atattcctat
      661 cacacatcca attatttatc attgtcttga aattgtttgc atacttaatt taatccaatt
      721 gaaacacccc agcatagaat cccctgtaaa atagaagttg gattaaatcc taacatctat
      781 acagaaaata ctactccaag cacaagcaat ataatggaat atatttatca cttaattttt
      841 tatacttttt aaatcccata cctaaaacat taagtgcagc tattagaatt aataattgtt
      901 gtggtataaa attatgcttg cttcatattt attcattttt tgctataaaa gttcttgttt
      961 tacaaaaaac atttgttttg tatcaaaata atacttataa attacataat tctcataaaa
     1021 atttctagta ttacttgtac tcttaataaa taatagccaa caagtacctt aaatcattat
     1081 atctatatct aataagaaac acagtaagat aattttttcg cccataactt aataaaaact
     1141 gttgatatta gtagcaattg aatttagtta atttatttat aatatacata aatttaaata
     1201 ttacgaataa agtattataa ataggatact ttctaaaggg aggaaattat gatagataat
     1261 caaaaatatg ttattttatc actagaatta catttatttt tttcaagaat tatgaaagag
     1321 catgctcttt ttttagaagc aggattcaca aataaaaatt ataatcttgc tatggaagct
     1381 gaccactata aaaagcaatt tgaagattta ttatcataca ctgttagtgc tagtaatggt
     1441 ataattagac ctgatatatt atattcagaa gagcttgtaa ctactctcac atcagttgca
     1501 gaacaaaaaa cagaagagtt tacagggata gaaataaaca aaaacatcac tacaagagaa
     1561 ttaaatctac aaagtggtgt aaacccacaa gttggtcaag acttagtgaa ctatgtagct
     1621 caacttaact ctgatgcaat aagattactt gatgggctta ttaattttaa agaaagagtc
     1681 ttagatggtg tactatcatg tactatattt acatcaaact accctctact tcttgaacat
     1741 ataatacatg aagcaaattt atatcgttct tatgtagttg accttgaaaa taaaatagat
     1801 attgagtcaa aaaacgctaa agaaatagaa ttattctggg accatattat gatggaacat
     1861 gctctgttta tgagaggatt actagacccc tcagaaggtg aactaataaa tacttcaaat
     1921 gattttgcta taaaatttaa tgaattaatt gaaaaaacaa acgaaatgac tgattctaat
     1981 atcaagaaca ttacagaaga aactctaaat gaaactgttg agtttaaaga ttttaaagaa
     2041 gcaggagcat caggaataga acagtgtaag ataaaatcta taatattacc acttttagca
     2101 gaccatgttt taagagaggc aaatcattat attagaatat tggagagtta taaaaacatg
     2161 taattaaaaa ttacttttaa aataatcttt gcatatttag ataaaataaa ggtacagtta
     2221 actgtacctt tattttttat aaacttataa aatttaaaca agttattcat aaaataaaat
     2281 aataatcatc tataacccac aactttattt tatattaaat aaaaagtatt agtgattatg
     2341 ttttataagt atttctttat tcagttattt attaaaaact aatagtaaat cttatactaa
     2401 tcgcatattt atgttataac tatattgtaa ctattttcgt aatcttagga aaagattact
     2461 tataaaatta accttataca ataatatatc gtataatctt aattagcata atagttacaa
     2521 tattaaaatt taaatatggg agtgatttta gtatgataag acaaacacca ttagagaaac
     2581 gatatgacaa gctaggtcct catattgtaa cagcactcaa aaaacgttat tttgatgctt
     2641 attactgtaa aactagaaat gaagctttgc aacaaatttt agatttaatt cctcaaaatc
     2701 atgtagtatc atggggagga tctgaaacac ttaaagaaat gagcgtacaa actgctgtta
     2761 gagagaaagg atttaaagtt attgatagag atttagcaaa aactccagaa gaaagaactg
     2821 aaattatgcg tcaagcactt ctatgcgata cttttttgat gagtagcaat gcaattagtg
     2881 aagatggaca actctttaat attgatggaa atggcaatcg tgtagctgca atgatatttg
     2941 gtccaaaaaa tgttatagtt gtagctggta tgaataaaat tgtaaaaaac attgatgatg
     3001 caatacaaag aactagaaca attgcatctc cagcagttgt tcagcgtttt caagatgtca
     3061 atacaccatg ctatattaat ggaagttgta tagattgcac aagtcctgaa agcatttgtg
     3121 catacatggt tactacaaga atcagtcgtc cagcaaaaaa aataaaggta atattggtag
     3181 gagaaaatct tggtctataa aatatacata catgtaaata gctctataaa taataaaatc
     3241 atatgaaata acttatttct aaaagtggta gaataaaagc ttctacaaga ctttcattct
     3301 accactttta tattctttta atttgtgttt ctatattatt aattgctcca attttcatat
     3361 atattactaa ctatttttat tttcataatt tttttgttct tcatcaagct gtttataata
     3421 atctttatta tagtcagcta gataatctat accacctcct gtaatcacat ttaataattt
     3481 cattgcagat tcttgattaa ctttacaaac ataattatca ccagatttaa caagctctaa
     3541 tgtaatatta aattcttttt tctttgcaga atcaatatct ttcatagttg gatttggcat
     3601 catttctcct agtttaggag gattcttttt taaaatagaa accatatcag tattgttaat
     3661 ttttaaatct acagtcactt tatccttatt attctttata tctgaaattt cccaagtcat
     3721 atttttagaa tacattttaa atccttcttt atcttcgtat ataagattac ctaaccctga
     3781 ttttgggaaa tacttatcaa cagtatctgc atcttgtgtt tttattgaat taaacatact
     3841 atccacttca ttttttatct tattatcatt agtacaacca gctaacacca gtactgatat
     3901 tgcaaacatt ataatacata taataaattt cttcattaaa ttatatcccc ctatactttt
     3961 ttgcacaaat attattctct tttttatctt ttgaaaaagt tgtagtaatt gcattttgtg
     4021 gacaaacttt tatacattca ccacacctaa tacagtctgg actatttaca tctttatata
     4081 ttggtatatc aagcttacat tttgtttgac atgctgtaca atttgtacat ttatctttat
     4141 caattttaaa tctatatatt gaaataggat taaaaaaacc atagattgct cctaaagggc
     4201 atatatactt gcaaaatggc ctataagtaa tgattgacat caataatatc aatagcaaaa
     4261 tatttaactt ccagctaaat aaaaatccta ttgattctct taaattctca tttcctaaaa
     4321 taagtggtat tcctcccaaa agtgttcctg aagggcaaat ccatttacaa aaccaaggat
     4381 ttccaccccc tgctacattt acaatagcaa ctggcaaaat aattacaaac attattaaga
     4441 ctatatactt tagatatttt agatatttat caccataaac tttttttatc tttactggaa
     4501 agggtacttt atgtagtaaa tcttgtacaa gtccaaaggg acaaagccaa ccacaaacaa
     4561 atctgccaaa aaaagcacca aatgccatta aaaaaccaac aacataaaat gagaatttat
     4621 actctctgct tgataaaact gcttgtaatg aacctattgg acatgctcca agtgcacctg
     4681 gacatgaata acaattcaat ccaggtacac ataatttttt actttctcct ccatatatag
     4741 ttccttctaa aaatccattt acatatccat ttgttaatgc tgtaaatgca acttgagtaa
     4801 taagtcttat attattattt accttagata ataacttcat tcctcttctc ctaaccaata
     4861 ccaatacact caagacaaat cataattgct ttagttaata ctgtatttgt ttctccacga
     4921 tatgtaccta atgcaataaa tataatacta attgcaataa tagaaatgcc ttttttatta
     4981 tctttaataa aattactcat tggcttttac catttttagt ctttcatcta taattttttt
     5041 ccaatcttcc ttactatttg cacctacaac cttctcaccc acaaagtttc ctttcttgtc
     5101 tacaaaataa gttgttggaa actccataac tcttttaaaa tcagtttttt taagttcttc
     5161 agatacagtc aattgttggt aagttgcatc tgactttttc ataatgtctt taactaaatt
     5221 tttctcttca tttgaaagac cagttctcat atcagtttta tcaacttcta caactaatcc
     5281 ctttatagct acattggaat tattactctc atattctttt gataatgctt caagctctgg
     5341 catttcaccc acacatggtc cacaccaagt agtccagaca ttaataagag taagttcttt
     5401 atttgaaaat atctcttttg ttaccttatt tccatcaaca tcctccgtat ctaaattact
     5461 aaaccattca ctattattct tgtttttttc tactggctta gattcttttt tgctacatcc
     5521 agaaatcata cctaaaacac aaatacatcc taaaactact atgaaaaacc ttttcatatc
     5581 tcacactcct agaatttata tagtatataa aatcgctgct tgaaataaaa ataacttatc
     5641 ttctatatta aagtaattat atttaataaa taagagctaa tttaaaaaaa gatatacagt
     5701 taaaatctat ttcttttcag acaaaatctt atatatatat aatagcttgt aaatcttaag
     5761 attatataca tatatttcta aagattttct taagaaacag ttagatttta ctaatataag
     5821 tttattaatt agcattatac taatttatct taatatgatt ttttgttgat tttaagctgt
     5881 ttatcgtata aataaaattt ttcttgacta tatagttact atatagctta ttatatatag
     5941 agagtaataa aaggaggtaa aatttatgga aaatttattt acaagaaaat tcactacttt
     6001 tgaatttcta aaatttgttt ctcctgcaat tatatccatg atatttatat ctttgtacac
     6061 aataatagat ggcatctttg tatcgacatt agttggttct gatgctcttg ctagtataaa
     6121 tattgtacta cctataatta accttgtttg tggatttgga ataatgatgg caactggtgg
     6181 aggtgctatc gtttctatac gtatgggtga aaatagacag gatgaagcca actctacatt
     6241 ttcttttata gttttgtttt cattgattgt tgggatttta ttcacagtaa tctcatattt
     6301 ctttatcaaa gaaatatcta ttttgcttgg tgcaacagat aagttattac catattgtat
     6361 aacttatggt aaagttatga ttttatgtac accattttat attttaaaat ttatatttga
     6421 gtactttgca agaactgatg gaaattctaa atttagttta tttctatcag tcattggtgg
     6481 tgtaacaaat ataatattgg attatgtatt tattaaatat tttggaatgg gtcttttagg
     6541 agctgcagtt gcaactgcta taggtattat tttaacttgt gttttaggta ttatttactt
     6601 cttatctaat aaatctacac taaaattaag aaaaccaaaa accgatttta gacttataag
     6661 agatactatg ataaatggtt cttctgaaat ggttacagaa ttatctacag gaattacaac
     6721 attcttattt aatgtagtag ctttaaaatt agcaggagaa aatggacttg ctgctcttac
     6781 tatagtattg tatgctcatt ttttaatgac atcagtctat ctaggattcg ctgctggagt
     6841 gtctccatta ataagctata attttggtgc tgaaaacagt gataaattaa aagaaacatt
     6901 taaacattct ctaaaattta tatttgtttc ttctctttta gtgtttattt ttgctttagt
     6961 atttgcacca tttattgtta gggtctttgt aagtccagat aacacagtat ttaaactagc
     7021 cttacaagga ttaaaaatat ttgcatttgc ttttttgttt gttggtataa atatatttgc
     7081 atcaggattt tttacagcat ttcacaatgg aaaaatttca gctattatat cttttagtcg
     7141 tgcctttgtt tttataatca taggaatcat aattcttcct cctatgttaa acatgactgg
     7201 attatggctt acagttccat ttgctgaggt tataaccata tttatatcta ttctatttat
     7261 aaaaaaatat aaatgtagat ataagtatta aaaattaata cttaaaatca acatttatta
     7321 aaactaataa acctgcttta aaatacaaat ttacaaattt gatttttaag caggttttat
     7381 tttagttata ataagtcatt tgcatactct ttaattggtg cttttctaag taataaaatt
     7441 ataaatatta tgcaaataac tataattcct acttttgttc caaataaaat aaaaggattc
     7501 tgaaatgaat aaataatttt ttctaaatac aatagcattt tatgcatatt tttagttgca
     7561 aaattaacta tataaattat cattaatatc ggtaatccta tcaatatagt aatactagta
     7621 acttttctaa ctctatatgt aaaagctcca agtaacactc ctataaaacc tatacatatt
     7681 tcatttatac atatttgtac aaaataattt aaataagtta gtggcatact tgatgttgaa
     7741 ggatctatca gtgctgatat agatgtccaa atcatatctc tctttagtaa aactgatagt
     7801 tctatactgt aacctgttat aatttctata aataacttcg ataaaaaaat caaaactata
     7861 cctaaaatag aaatcacaaa gcttaaaata attaaatcta tgacaatagc ttttatacaa
     7921 ctttttctat ctgctcttat acttaaagct cctgaaaagt ctttatttgc tatatttact
     7981 ccatacacaa atagcagtat agttatatat gttaaaatag gattcacaat cgtggataaa
     8041 ttagttttag atgcttctcc aaaaatcttg agaataaaca ctggcaaaat attcataaca
     8101 attcccacaa tcataaatat aattatatac aatttagtat ttttattaaa aaattttata
     8161 tatggcttta attcattcaa ttacaattcc tccttcttag tcatgttaac aaacatatct
     8221 tgtagcccta tgtatcctac atcaatattt gaatttttaa gtattttttc atcactttca
     8281 ctaaaatcac catagtaaaa ataagcaact gcatttccaa atgccttttt aggttttata
     8341 ttttttatac attctaattt ttctaactct tctttatttc cagtaatata atgagctttt
     8401 tgttttatga catcaatttc ttcatctata ataatttttc cctcatttaa tactattaca
     8461 tgctccagta aatcatctat ttcatcaatc aaatgagttg atattattat tgtccttgga
     8521 ttttttatat aactatctaa aattatgtta taaaactctt gtctatttac tgcatccaga
     8581 ccaattgttg gctcatcaaa tatggtgata gctgaattag aacaaatacc tattatattt
     8641 gaaagtatag ttttcatacc tcttgacagt tgtttatact tttttttagt atttaaatca
     8701 aaatatttgc ataattcttt ttctaagcct ttatcataac ttttataaaa actagaagaa
     8761 aattcaaata tctgacctac tttaaaatct ggactataaa attctttttc cctgacaata
     8821 caaacttctt ccaaaacttt tatatcttct tttgggttct ttcctaatat ttctatctca
     8881 ccttcatttt gaattaactg atttaccatt atatttaata atgttgtttt tccagctcca
     8941 ttcttaccta ataaaccata tatcttattt ttttcaaagt ttagagacat attattaaaa
     9001 atattttgct tcttaaaact gtgagataaa ttttctatct taatagaact actcatatat
     9061 taatcctcct tgaaattaat tataatatca accaattctt ctctatttat ttctaatttg
     9121 ttagcttctt gaagtaggtt ttttacaaaa ttatgtttaa aattttcttt tctagcttct
     9181 tttataatag tttttgcacc atctgataca aacatcccta tccccctctt cttatataaa
     9241 atatttttat caaccaatat atttatacct tttaatactg tagctggatt aattttataa
     9301 agctttgaaa gctctgttgt tgatggaacc tgttcttctt cttttattcc atttgatagt
     9361 atctcatctt caattgctcg tgctatctga ataaatatag gttcttcatt atttaatact
     9421 aatttcatag gtgcctcctt tctccattag ttagttactc aactaattaa ctatataact
     9481 tataatatct tgaaaaatat tttctgtcaa tactaaataa aaaacagagg gaaaattccc
     9541 tctgtttgtt gttctttata tttataatta aattttaatt tttgtaatcc tatccataag
     9601 ttaaaaactt taataatctg ttgtatcttc attttttaat attttacata ttgagctagt
     9661 tcctaacctt tctgctcctg cctctataaa tttttctgca tcagaaattg atttaactcc
     9721 ccctgcagct tttattttta cattttttcc aacatgctct ttcataagct ttatatcttc
     9781 taaagtagct ccacctgttc ccattccagt agatgttttt ataaaatctg aacctgacat
     9841 tgttactatt tcacacattt ttattttttc atcttcatct aaataacatg tctctataat
     9901 gacttttaat actttatctc ctatagcttt ttttatttct tttatttctt ttcctatatt
     9961 atcataatct ttatttttta tatctgaaat gtttacaacc atatcaactt catctgctcc
    10021 attttcaata gcatcttttg cttcaaatac ttttgtagca gtagtttgat atcccaaagg
    10081 gaaccctatc actgtacata tctttatttt accttttaga tattctgatg ctcttttcac
    10141 atatgatggt ggtatgcaaa ctgatgctac actcatatct acagcttcat cacataaaat
    10201 tttaatatct tcccatgtag ttgtagcttt taaaatagta tggtctactg tttttaatat
    10261 atgtttcata aaatcctcct aaatttataa ttaatataat tagattactt ttttaaatgc
    10321 aattttctct ttgcaatatt cagtatcata tcaacctctt caactttaaa aataatcatt
    10381 agtagtgtat aaattccacc tccaactata actgaaatag ctagtgatac aaactcatta
    10441 aatgttccta ctcccaaaat tccaaatata aatttatacg taaagtatga taaaacaccc
    10501 ataattaaag atgcaactac cgatttcaaa gttgctttta ttattttatc ttgtccaaaa
    10561 tatccaactt ttctctttag gttcaagaag agtaacaata tacatgcaat tgatgatgaa
    10621 ctagttgcaa gagcaagacc accatgagcc attggtttta ttaaaactaa gtccaatact
    10681 atatttaccc ctacagatat aatcccattt accataggtg tttttgtgtc ttgtaatgaa
    10741 taaaaaacct ttcccaaaat atctcttaag ccaaatgcag tcataccaac tgcataaaaa
    10801 attaaggcag ttgctgtcat ttgggttgcc ctcgcatcaa aagcacctct ctcaaaaatg
    10861 attctaacaa caggagttgc aaaaaaaata gaagcaactg aaataggaat catagaaatt
    10921 attatcatat ttatactaga tttaactgaa ctagtaaact tcttttgatt attttctgca
    10981 cttaacttag ataacatagg atacataaca gatactattg aagctgtaaa tgtccctgta
    11041 acaaaaccat ttaatctatc tgcataagta agtgctggaa tgcttccttt aactaatgtt
    11101 gaggctaaag ttgtatctac caatgagttc acttgattaa cagcaacacc tataaatact
    11161 ggtgaaagta atgctagtaa tttaataagg ctatcatctt taaagtttaa gtagtataag
    11221 tatttgtagt tcgttttttt aacaaaaaac atgtaaaaga gcagctgaac taccatagca
    11281 accacagcac caattggaag tatgtatggt ccaaatacgg tacttaacat tattgaaata
    11341 attattacta tattataggg tatacttcca aatccaacta caataaagtt ctctttaatt
    11401 tgtaaaaatg ctgacataac acttgtaata cctatgaata ttattcctgt tctgaacctc
    11461 ccatgactaa agtcacaggg ttcctgcttc atagaatttt gcatactaaa atatgtctta
    11521 ctaattctcc acaggctatc cccgtagttc ctacggttct tacataagtt atttattttg
    11581 aatcgttatt aatcttaatc cttcttttaa tatatttata cttgcattta tatctctatc
    11641 gtgagtttca ttacaactag gacaaatcca ttctcttata tttaagttct taacttcctc
    11701 gtttttatac ccacatttat tacatatttg tgaacttgca aagaatttac ctacctttac
    11761 aatttgtcta ccatgccaat tagccttgta ttctaattga cgaataaact ctgaccatga
    11821 tacatcagaa attaagcgag atagtttacg atttctaatc atattcttta cttgtaaatc
    11881 ttctatgcaa ataatatcgt tctcttttat taatttagta gatagttttt gtagaaaatc
    11941 atttctttga ttagctatat gttcttgaag tcttgcaact tttaatcttg ctttatttct
    12001 atttaaacta ccgattgttt ttctcgataa ttctctttgt aatttagcaa gtttgtttaa
    12061 tgacttctta agatacttag gattttctat aaattctcca caacttgaga tacaaaattc
    12121 tttaattcct aaatctaaac ctatctgatt attagtattt tcaaatgctt caatatctac
    12181 atcagtacag cataatgata cataatatct atcacttggt tctttagata tagtagcatt
    12241 aagtattctc cctttaggta cttgtttatc ccttacctta ac
//
LOCUS       DAEPUT010000112        12054 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.115, whole genome shotgun sequence.
ACCESSION   DAEPUT010000112 DAEPUT010000000
VERSION     DAEPUT010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12054
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.115"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            183..515
                     /locus_tag="KRL22_003426"
     CDS             183..515
                     /locus_tag="KRL22_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBH1273864.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            677..862
                     /locus_tag="KRL22_003427"
     CDS             677..862
                     /locus_tag="KRL22_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273865.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            889..1974
                     /locus_tag="KRL22_003428"
     CDS             889..1974
                     /locus_tag="KRL22_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH1273866.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMGNMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            1967..2425
                     /locus_tag="KRL22_003429"
     CDS             1967..2425
                     /locus_tag="KRL22_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273867.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            2460..3551
                     /locus_tag="KRL22_003430"
     CDS             2460..3551
                     /locus_tag="KRL22_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1273868.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            3556..3780
                     /locus_tag="KRL22_003431"
     CDS             3556..3780
                     /locus_tag="KRL22_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273869.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            3790..4353
                     /locus_tag="KRL22_003432"
     CDS             3790..4353
                     /locus_tag="KRL22_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273870.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVNKEFKKSKAYSDFITLYNKSVDALKNKATFKKVLK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            4314..4943
                     /locus_tag="KRL22_003433"
     CDS             4314..4943
                     /locus_tag="KRL22_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273871.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            4983..5120
                     /locus_tag="KRL22_003434"
     CDS             4983..5120
                     /locus_tag="KRL22_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1273872.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            5120..5872
                     /locus_tag="KRL22_003435"
     CDS             5120..5872
                     /locus_tag="KRL22_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273873.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            5885..6370
                     /locus_tag="KRL22_003436"
     CDS             5885..6370
                     /locus_tag="KRL22_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273874.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            6377..6526
                     /locus_tag="KRL22_003437"
     CDS             6377..6526
                     /locus_tag="KRL22_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273875.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(6662..7483)
                     /gene="yidA"
                     /locus_tag="KRL22_003438"
     CDS             complement(6662..7483)
                     /gene="yidA"
                     /locus_tag="KRL22_003438"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBH1273876.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            7976..9670
                     /locus_tag="KRL22_003439"
     CDS             7976..9670
                     /locus_tag="KRL22_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBH1273877.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETSEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      10002..10112
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            10216..10587
                     /locus_tag="KRL22_003440"
     CDS             10216..10587
                     /locus_tag="KRL22_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HBH1273878.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            10683..11630
                     /gene="trxB"
                     /locus_tag="KRL22_003441"
     CDS             10683..11630
                     /gene="trxB"
                     /locus_tag="KRL22_003441"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH1273879.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            11715..12032
                     /locus_tag="KRL22_003442"
     CDS             11715..12032
                     /locus_tag="KRL22_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HBH1273880.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
BASE COUNT         4774 a         1253 c         2151 g         3876 t
ORIGIN      
        1 tattcattaa aattaataaa aatagaaaaa aatcaatcaa taatttaata aaaatagata
       61 aatactatat acacttttaa taatatagtt aatatctatt ttacagataa ataagaataa
      121 acttataata taattgtatc tgtaaaattt tgtaaaatat aaaaagtata gggggaataa
      181 aaatgaaagt agcttatatt tttagtagta ctaatacaca taaaattcta gacaaaatga
      241 taataccaca acttgaacaa ggaactcatg gagtagacgt tctagggatg tttttcttta
      301 tggataatac cttattttta tctaaaggta atcctgtagg cgagagacta agtaaattac
      361 atgaaaaaac tgatatgata ataatggctt gtgaccaatg tgctatagaa agaggtatag
      421 agaataattt ggttgatgga gctacaattg gatgtttccc aaacctatat gcttgtttag
      481 gcagtgcagg tgtggaccaa gttataacgt tataaattag tataggatac aatccataga
      541 aaaatttatt ttctgtggat tattttaagt aaaagataaa ttgtttaaag taggggatga
      601 acaaatgtct aaaattttag ttgaatttat aaacacttga ccatcttgtg atgaacatgg
      661 agtgtttata aaaaaaatgt cagaaaagta tgctgataaa ttggaaataa aattatatca
      721 agcagggaaa gatttttcgt atataaaaaa atatgggatt ataacaaaag gaactttaat
      781 aataaatcag aaaaagaaat atgatagatt aaataaagat acaattgaaa gggcaatagt
      841 agaagctata aacaataatt aaaagtttaa aaattaggag tatcaaaaat gaatatatta
      901 gaaattgttt taaatggagt taaagatact atagtagctt ctatagttac actgaatgga
      961 gcatcaggat ggcttatgat aagttttata ttggcaggtg tacttcacaa tgttttaact
     1021 ccaagaaggt ttcaaaaaca acttggaaat aagaaatttt cttctttaat taaaagtact
     1081 atctcaggaa tgtttttacc aatatgtagt tgtggagtaa taccacttgg aataagtatg
     1141 tattattcag gagcatattt aggaccagta cttgctttta tgacatcaac tccaataata
     1201 aatccaatag ctgtagttct ttgtctaggt cttttaggtc ctaaagttac aatcatttat
     1261 ctaatagctg gttttttagt accattttta gtaggatttt taggaaattg ttttggaaaa
     1321 gaagaattat cacttcataa tgattcagag gaagaagtaa tagaattaga agaagaaaaa
     1381 agaagtttta tgggaaatat gattgatggt cttaaatggt cttttggtga attagccctt
     1441 actattagta aatatgtagt aatgggtatg gtttttgcag gatttataac aactattttt
     1501 ccaaatagta taattcaaaa atatttagga aatccaggtt tgctatctct tggaagtata
     1561 gcaatacttg catgtgttat gtatgtatgt gctgtaggac atataccgtt tatagcagcc
     1621 cttgttgcaa gtggagcatc tcctggtata gcaataacat ttctaatagc tggagcagct
     1681 acaaatctac cagaacttat aagtatgttt aaacttattg gaaaaagaac tgttattata
     1741 tattctgtaa ctttgacact gtcttcaata ataattggat atataacaaa tttactttta
     1801 gtgaataata actcagtaaa tttagatgca acaaattctt caatacagtt ggcaaataaa
     1861 ctaatgttaa atatacctga tagttttgag tatgtatgta ctattttaat tattttattt
     1921 gcatttaaat caataatacc aaagatgaaa gaggtcatag gaaatcatgc ttaaaaagat
     1981 agttataata tcctgtatag tagttgtgtt aatcatttta tcaaaaatag ttgatgataa
     2041 catcaaagaa gatgcttcta ttccaaatgt gaataaagaa acattagaat attttagaaa
     2101 aaattataaa gaagacataa taacttgtgc tgaagaagac ttaaataatg atggaaaaaa
     2161 agatttagta gttatatata aaaaaagcaa taattcaaat gaaatggtag tcgtagtttc
     2221 tgataaaaat agccactata taacaaagcc aataccagca cctatagaga atcaaacgat
     2281 aacctttaaa aatattgatg ataaagcacc aatagaagta attgtatcag ggtctaaaaa
     2341 tggtaatgta ggatatgcta tttacagagt agagggtaaa aaatttgttg atttatttgg
     2401 cgaagatatg gacaaatgtt gctaaaaata aaaataatac ataaaggtgg gaaatttata
     2461 tgaaattatc taagaagatt caagcattaa tcttatttgg tgtaatgggt acatctatat
     2521 taacaggatg tagtagtaaa ccaaaagaaa aagaagaagc aaaaactgga aaagatgatt
     2581 atacaataac agtaggttat tataattgtg accatatgac tgcgggacca gtagcagaat
     2641 cggcaggaat atataaagat ttaggtctta atgtaaaaac tgttggaaat ggtaaagttc
     2701 ctgaagctat ggcagcagga aaaatggatg caggttacat aggaactaag gggttagttg
     2761 gagcaatacc taagggttcg ccaataacaa tagcagctaa caaccatact ggtggttctg
     2821 aatatttaat agtttcaaaa gatataaaag aacctaaaga tttaataggt aaaaaaattg
     2881 caacagatat gagtgatttc ttatggacaa gtgattatgg tccagaaaca ggtctaccaa
     2941 ctgacccatc aaaatatgaa gttgtaaata tggattcaga caaagataaa tatttagctc
     3001 ttaaaactgg gaaaattcaa gcttttacat cttgtgaccc ttggggttct gtagctgaaa
     3061 atgacggtgc aggaaaaata atagcatcta ctcaatataa agaaaaagct aatggcaaag
     3121 aatataactg ttgttcattc tcattaaaca aaaactttat aaaagaacat ccagatttag
     3181 caaaaaaatt ggttctagca catacaaaag caatagaata tatatataca aatccagctg
     3241 aagcagctaa aatatttgca aaatattata atgtagaaga agaagttgca cttagaacta
     3301 tctataagaa gactgttgga gaaggtagaa ctcttacttg gaaagttaca ggtgaagaat
     3361 ataaaaataa tttacaaatg tataaagatt taaaggcttt agatgatata cctaaatatg
     3421 aagatacgat tgatacaagc ttattggact cttgtggagc tgatgatttt gacaaattta
     3481 taaaagaaaa agttaaccca gagtttcctg aaggtatgag ttatgaagac tggaaagcaa
     3541 aggtattata aataaatgga gaatatgaaa aatataataa tactttttat cattattttg
     3601 ggaagtatat ttataatatt ttttaatttt gaagataaag aagaaataaa aggaaaatta
     3661 agaatagggg tatctgatga tacctctggt tttgtaataa attatatggt aaatagagac
     3721 tactttgaaa atataaaagt aagtgatata atggatattt ttacaattaa tgattgctga
     3781 gcaagtacaa tgcagtgggc tctgagttca gaggaaatag atatagcaat catatgtaaa
     3841 gatgctgcaa aacaatatgt aaatgtaaat agtggatttg aaattgttgg tactgtagtt
     3901 caaaattctg atatatttct attaagtgat aataatcctg aaaagatagg agtcattcaa
     3961 aatagagatt accagtcaga attggttaaa aaatactaca agaatgtgga agtagctccc
     4021 ttattaggga ctgcactagc atatggatta gaaagtaatt tagtagatgg tgttgtaata
     4081 gattgcataa agtcaattgg gttagagggt aaaagaaaat ctacaactaa attaggagat
     4141 tatgatacct atgtattagt tgtaaataaa gagtttaaaa aaagtaaagc atatagtgat
     4201 tttataacac tttacaataa aagtgttgat gctttaaaga ataaagctac atttaagaaa
     4261 gtattaaaag agtacaggaa tataagaaat atagatatgg aggaaataag caattggaaa
     4321 ttaaaatttc taaagataaa agcgatagat taactaagaa aaaaactgat ggtagtatgg
     4381 atattttata taaaataata ctattagtta ttatattttt agtctggcat tttgcagcaa
     4441 aagatatagg gagttctttg ttacttccaa tgccagtaga tgtaataaaa ggtttctttt
     4501 tctgtgtgac agatgcagag acagtcacta atctttttat aacattgcag agagtactta
     4561 aaggttttat gtatgcatta ttgtttgggc ttccaatagg atttattatg ggattttcta
     4621 aaacttttga aagggtttta tctccagtag tagattctgt aaggcaagtt ccaataatgg
     4681 catgggttcc tcttactata gtatggtttg gtataggaga tggtccaaca atatttttaa
     4741 tagctttttc aggggttttc cctataattt taaatactat tcaaggagta agagcaatat
     4801 caaaggatta ttataatgca gctagaagta tgggagcatc gccaattgtg atatttacaa
     4861 atgtaattgt tcccgcatct cttccagata tactaactgg ttcaaggatt gctataagta
     4921 caggatggat gtctgttatc tgagccgagt ttatagctac gagtgccggt ctcggttact
     4981 caatggtaca agctcaaaca ttaatgcata cagatgtatt aattgggctt atgatatttg
     5041 cagctttaat aggatttata atagataggg tattaaagtt tataaataaa atcctttgta
     5101 gatggaggtt tgcagattaa tgaagttaag tgtaagagat ataaataaga catttgtaaa
     5161 taatagagta catacaaagg ttttagaaga tataagtatg gatatagatg atggacaatt
     5221 tgtctgtctt ttaggaccat caggttgtgg aaaaacaact ttacttacta taataggtgg
     5281 gtttcaaaaa tcagaacgtg gagatgtttt tataaatgat aaaagagtta aaaaaccggg
     5341 catagataga gcttttatat ttcaaaatta tgctttattt ccttggaaaa ctataagagg
     5401 taatgttcta tttcctatga aacagcagaa aataccaaaa gaaaaaagag aagaaatgct
     5461 agaagaactt ttggttatgt cagacttgaa aggaaaagaa aaactgtttc cgcatcaatt
     5521 atctggagga atgaaacaaa gagtggccat gataagagct ttagcatgta atccagaggt
     5581 attactaatg gatgaaccat taggagctgt agattttcaa atgagacaaa atttacagga
     5641 agagctagaa cgaatatgga taaagaagaa aataactgca ttaatggtaa ctcatgatgt
     5701 tgatgaagct gtatatatga gtgatagagt tatagtaatg tcgagagata aaggaagaat
     5761 tattgatgat ataaatatag atattccaag acctagaatt agaggaagcc aaaaatatga
     5821 agagtacaaa aacaaattaa ctgatacttt atcaaagtgt tatgaagttt aaagaggagt
     5881 agacatgagt caaatagaaa aatacaatag tttggataat acacaacaga aaataagaat
     5941 ctctattatg gatatgataa tagataaagg ttctagtgtt acacttcaag aagtgactga
     6001 atatgtaagt aaaaagttga atatagaaaa agaatatata gaaaggacac tacaatattt
     6061 tatttataaa aatataatgg ttgttgatgg gaatagtata aattttatat atcctgtatc
     6121 agcattgcca acaaatcata aagtaacttt gagagataat agaagtttca gtgcaatgtg
     6181 tgctatagat gctataggaa cctcttgcac attcaaccaa gatataaaaa taaactctat
     6241 ttgtagtgct acaggtaagg aaatagaagt aattataaaa aatgaaaaga ttgagtatgt
     6301 gaataatcca aacttaagag tgcttcatat aaatcttgat aagcatctaa attgggctgc
     6361 tagttgctga aatataatga atttcttctg gacgaagagt gattttgatg cttggacaaa
     6421 cgaagcggga ttatctgatg atgaagatat atattgttta gatattaatg aggcaatagt
     6481 agaatcatat aaaatattta aactcaaaca aaaggtacta tcatagatat acatatatga
     6541 aaaactaaaa atgaccttta gataaaaatg ataggtaata tccatactat ataaattagt
     6601 atagagtagg gatgtgaaaa gtatttaaat ctaaaggtat atttttagtt tttttagatg
     6661 attagatagc cttattaagt atatatttat ttataacctt tgcaactcca ttttcattat
     6721 tagtatcagt aacataatct gcaatttcct ttatactatt acgtgcattc cccatagcca
     6781 caccaagacc tgcatacttt atcatatgtt ggtcattttc ttcatcgcca acagcaatag
     6841 cattttctat aggtatattt agattcgtac ataatgtttt aagagcagtt cctttattag
     6901 tagttttacc taaaaattct agataaaaag gagcagacct tactatagta tatttattga
     6961 ataaattttt aggtagttgc tgtatgattt cttccaatct ttctggttca tcaactatca
     7021 taattttaca gattttaata gattcatcaa ttttatcttt ttgtatatat ttgacttcta
     7081 tattatttaa tttcgcttca tgaagtgtat atttgccagg cgtttcattt ggtgtaatta
     7141 aatttgtcat tgtatttatg tgtattttag tcttatattt tttacaaacg ttattatata
     7201 taaaatcaaa atcatctaaa ctcatttcta catcatgtat gattttctca cttttaactt
     7261 cttgaataat tgctccatta aagcatataa cataatcacc ttcatctgtt aaatttagtt
     7321 gatttagaag ttcttttaca ccaggaagag gtctgcctgt tgttataact acttttgccc
     7381 cagccctttt tgcctcctga atggactcaa agacttcagg agtaatcctt ttttgtgtat
     7441 ttaatattgt tccatcaatg tctagtgcga ttaatttgta catatcaacc tccaataaat
     7501 tatatactca aatttcctgt gaaaacgttg acacagctag tgtcgaacaa agtttcagtg
     7561 ggaaatatgg tttgttttgt atactattat atcaagagat aagtaattta gaaagtttaa
     7621 taatattaat tttttgataa aaatattact tatgtgagat gagaatgtaa aaactttgta
     7681 atcaataatt ccaaaattct taattacaaa taatggtatc gtttgcattg ttaatataaa
     7741 taaatgtata ttatatagtt agaagtttga ataaatagac tgatggtaat ttgttatatt
     7801 agttagtttt gtgttataaa atattgtaat tccattaatc atatgttatt attcaacatg
     7861 attataatat aaagaatatt tgatatatat aataatttat aaaagagtat tacatagtac
     7921 atgtaaatct atatttataa atacaataaa gtaaagttgt aaaggagtgc tttaaatgaa
     7981 gttttcagag tttaagtatg aaagacccaa ttataatagt atgaaaaaag agtttttgag
     8041 ttgtgtagaa gatataaata attctcgtaa ttataaagag caacaaaaaa atatacataa
     8101 gattaattta ttaagaaata aaatagaaac gttgtcaaat atagcttcga taagatatag
     8161 tacagacaca tttaataaat tctacaaaga agaaaaaaat tattgggatg aatatatgcc
     8221 tttgtatgaa gaattaaatt catattttta taatgccatt gtaaattcaa aatttaaata
     8281 tgatttgata aaagagtttg gagagcaatt tttcacaata gtagagtatt ctttaaaaag
     8341 tttttccaaa gaaataataa gtgaattgca ggaagaaaat aaattgtgtt cagagtatac
     8401 tagactttta gcttcagctg agataatgtt tgatgggaaa ataagaaatt tatctggtat
     8461 ggggaaattc atgtattcta agaatagaaa aacaagagaa ttagcaaaca aagcatatta
     8521 taatttcttt gaagaaaatg aaactaaatt tgatgatata tttgataaat tggttaaact
     8581 tagagataag atgtctaaaa aattaggttt tgaagatttt gtagagcttg ggtatgttag
     8641 aatgatgaga agtgactaca gagaatatat gataaaaaat gttagaaaac aagtactaaa
     8701 atatgttgtt ccaatggcaa atgagcttta tgaaaaacaa gctaaaagaa ttggtctaga
     8761 atatttaagt tacatagatg aaggcgtgga atttttaaca ggaaatgcaa gtttaaaggg
     8821 agattcaaga tacataattc aaaatggtaa aaggatgtat tctgaactgt caaaagaaac
     8881 aagtgaattt tttgatttta tgttagaaaa tgaacttatg gatttagaaa cgaagaaagg
     8941 aaaaggagct ggagggtatt gtacttatat accagattat aaatcaccat tcattttttc
     9001 taattttaat caaactgctg atgatataga tgtgttaaca catgaggcag gacatgcatt
     9061 tcagttgtat atgtctagat ggattgatat gccagaaatt aattttccaa cgcttgatag
     9121 ttgtgaaatc cattcaatga gcatggaatt tataacatgg ccgtggatgg atttattttt
     9181 taaagaagat acagataagt acaaattcac tcacttatca tcttcaatta aatttatacc
     9241 ttatggagta attgttgatg aatttcaaca ctatatttac aaaaatccta atgtagataa
     9301 gtcaaaacga aaagaaatct ggagattttt agagaaaaaa tacttacctc atagaaaata
     9361 tggtgataat tcttttttag agagaggttg ttggtggttt aaacaaggac atatatttaa
     9421 aaatccgttt tattatatag attatgtatt agctcaaatt tgtgcgttac aattttggaa
     9481 aaaaatgatt caagatagag atgcaggatg gaaagattat ataaatatct gtaaagttgg
     9541 aggaacaaaa tcatttttag atattgtgag tatgggaaat ttgtattctc catttgatga
     9601 tggctgtatt gagtctatta taggtgatgt taaatcttgg tttgatgaaa taaatgacag
     9661 caaattataa aaaattatga gaattttatt ttataaaagt gaaaaattaa aaaatatata
     9721 aaaagtgatt atttgttgtg aaaatagtct tgtttttaac taaattgata aaataaacta
     9781 aaaaagattt gtacttaaaa aaaaaagaaa atacaagaaa tatgcaatat caacatttgg
     9841 aaaaaaaagt aaaaatgtat acaaaataca tataaaaaaa ctattgcaaa ttttatagaa
     9901 tgtttatata cttaagtcaa cagagataga aaaaagctat ttatagaaaa caaaggataa
     9961 attgcttaat tttaaatttt ctgaaaaaaa taataatccg gatgaagagt atgggagact
    10021 gctttataaa aagcgaccga agggacaagt ttaatcttac ttacccaaaa gattagatga
    10081 aattctcagg taaaggtgac tgtacttgga cggggctctg aaaatgattt taacagggaa
    10141 gacaaattgg gagatttgtt tttcctgttt tttatttatc aagtaataaa taaaagtttg
    10201 aaagagagta aaaaaatgat aataattacg aataatccaa aagtaaaaga agaagttcaa
    10261 ggcagagaag ttttgtttaa agacacaact tatattggaa tcttagaagc aagtagagat
    10321 ttgatacatg aaggttatga acttttatct catccactct atgggagtgt aaagccaaat
    10381 gaaacacctt acaggactgt tatactaaag aaaggaaatc gtttggatat aaactcttta
    10441 accttaattg aagaagcaat catcactgca agtaaatttc agaataataa aaagactcca
    10501 aaatggacag aaagtgttca agatgatttt agagtaattg attatgatat attttataat
    10561 acaatacaaa gaatgcagta tgaataaaaa aatttgttaa aaagttatta aaacagccta
    10621 aatattaaat ctaatttaat attaaataaa atgagaaatt taattgggga ggataagtca
    10681 aaatggaaaa tgtgtatgac ttagtaataa ttggttcagg accagcaggg cttgcagcag
    10741 gtctttatgg agcaagagca aagttaaaaa ctctaatcct agaaaaagac aagactggtg
    10801 gacaaattgt aataacacat gaaattgcaa attatccagg gtcagttcca aatgcaacag
    10861 gaccaagttt aatagctaga atggttgaac agtgtaaaga gtttggagca gaaatgctaa
    10921 gagacaacat tgttgatact gagctagatg gagatataaa agttttaaaa ggggaaaagg
    10981 cagaatatag agcaaaagca gtaataatag gtacaggagc aacaccaaga aagattggtt
    11041 gtcctggaga aaaagaactt actggtaaag gggtttcata ttgtgcaact tgtgatgcag
    11101 atttctttga agattttgaa gtatttgttg taggtggagg agacagtgca ttagaagaag
    11161 caatgtattt aactaaattt gctagaaaag taacaattgt acatagaaga caaggattta
    11221 gatgtgctaa gagtgttgaa gaaaaagcaa aagctaatcc aaagatagag tttttattag
    11281 atacagtaat tgaagaaatc aaaggtgatg gaatattaga atcagttgta tttaaaaata
    11341 aagttactgg agaaactcat gaatactttg cagatgaaga agatggaaca atgggagtat
    11401 ttgtgttcgt tggattagat gctcaaactg atttattcaa aggtaaagtt gatatggatg
    11461 aaaaaggtta cataataact gatgaagata tgagaactaa cataccaggc gtatttgcag
    11521 caggagattg tagatctaag actctaagac aggttgtaac tgcaactaat gatggagcaa
    11581 ttgcatctat agtagctgag aaatacattg atgaaaaatt tgggaactag aatctgtaaa
    11641 ttaagaaata gtgtctgtaa atttaatgaa taatatttaa aattaaaata aaaatttcaa
    11701 gggggaataa gaaaatgtta gatttagata aggctacatt tgaagaagaa gttttaaatg
    11761 cagaaggttt tgtatttgtt gatttttgga gtgaaggttg tgagccttgt aaagctttaa
    11821 tgccagatgt tcataaatta gctgagactt atggggataa aataaaattc tgtaagatgg
    11881 atacaacaaa agctagaaga ttagctataa aacaaaaagt attaggtctt ccaactatgg
    11941 ctatatacaa agatggagaa aaagtagacg aagttactaa ggatgatgct acagttccta
    12001 atatagaaaa catgattaaa aaatatcttt aatatgttga taaattatta acat
//
LOCUS       DAEPUT010000113        12049 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.116, whole genome shotgun sequence.
ACCESSION   DAEPUT010000113 DAEPUT010000000
VERSION     DAEPUT010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12049
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.116"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            47..1051
                     /locus_tag="KRL22_003443"
     CDS             47..1051
                     /locus_tag="KRL22_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1273881.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGVKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKIIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            1177..2289
                     /locus_tag="KRL22_003444"
     CDS             1177..2289
                     /locus_tag="KRL22_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1273882.1"
                     /translation="MKIKRILMVCFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLPTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            2779..3540
                     /locus_tag="KRL22_003445"
     CDS             2779..3540
                     /locus_tag="KRL22_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273883.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            3543..4361
                     /locus_tag="KRL22_003446"
     CDS             3543..4361
                     /locus_tag="KRL22_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HBH1273884.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            4541..5143
                     /locus_tag="KRL22_003447"
     CDS             4541..5143
                     /locus_tag="KRL22_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HBH1273885.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     misc_binding    5755..5993
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6057..7976
                     /gene="thrS"
                     /locus_tag="KRL22_003448"
     CDS             6057..7976
                     /gene="thrS"
                     /locus_tag="KRL22_003448"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBH1273886.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            8744..9835
                     /locus_tag="KRL22_003449"
     CDS             8744..9835
                     /locus_tag="KRL22_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH1273887.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPRLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSSLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
     gene            10501..11841
                     /locus_tag="KRL22_003450"
     CDS             10501..11841
                     /locus_tag="KRL22_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1273888.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT         4874 a         1100 c         2099 g         3976 t
ORIGIN      
        1 taaataggat ataaaaatat cgtaaatgta tgaggagtga aatttaatgc gtttcaaaag
       61 aatattgata ttgatgttaa ctgtagcaat gatagctgga atgttggttg ggtgtgctaa
      121 taacccaagt aataatccta gctctagcaa agataataaa agtgatataa gcgataaaag
      181 taattcaaaa aaatctgtat caatgatact agatattgaa ggaacaaata atgaagctat
      241 gaataattca gctttattag cattaaacaa tgctcaaaag aaacttaata tagatacaaa
      301 caaagtggaa tcagatgatt cctcaacttt ttctaatagt atagatattt tatgtaatga
      361 caattacgat ttaattatag ctgtaggagc tagatttgca aaaccattgg agatggtagc
      421 caagaaatat ccaaagcaac aatttgcaat tatagactat gagtatgaca agcaaccttc
      481 taatataact tcaatttctt atgaagataa taaatctgga tatctagctg gattaattgc
      541 tggaaaaatg actgaaagcg ataaggttgg ttttatagga ggagtaaaga gctctagtag
      601 ggataaattt gaatcaggtt ttagagaggg tgttaaattt tctaatagta gtataaagga
      661 tatttcagtt gagtatgcag atgtttttaa agatagcaaa tcagtagaat ctatagctaa
      721 aaaaatgatg gataatggag tggatattat tttttctact actgaagatg attcaaaagc
      781 tgtaatagat gcagtaaggg caaaaaataa aaaagttata gcaacgaata aagaccaaca
      841 tgagttagct ccagaaaatg ttataagttc tattgtaaaa gattttgaga atcctactta
      901 taatctgata caaagctttg taaaaggaaa ttataaaggt ggaaaaatta tagaaaacac
      961 agttaagtct ggaagtactg ggcttgccca aaatagttct caaaatattc ctccagatgt
     1021 gttagaatat gttaataaga acaataaata atctactata atatccaaga atacttatga
     1081 ctttagttaa gaggtgaatt ggatgttata atagacatat atagaaagac atatgcagag
     1141 gtaggttaga cctatctaaa tcagggagtg aattttgtga aaataaaaag gatattgatg
     1201 gtttgctttg tagtagtttt tacaattttt atattagcta tatgtaattt tgattttggg
     1261 tttgataaag taaataagaa taattctaat atagatagtg ctaaatcgaa acagagtgag
     1321 tctaaaagtt tgccaacttc agcagaaaag gataaatcaa atagtaaaag taagaataaa
     1381 gaagatgaca cagaagatga ttcatatgta agaaaaacta ttggagtatt gttagatacc
     1441 gaaaacttaa ataacgaatc atataataac aatgtactat cagccttaaa aagggctgac
     1501 gaagattttg atgttaggat aaaacttgaa aaaccaaaga cttctaaaag ttttaaagag
     1561 agtatagaaa aactgcataa gtatgaacca gatttgataa tagcagttgg agccagattt
     1621 gcagagccaa ttaaagaagc tgctactaaa tatcccaaac agcaatttgc aatagttgac
     1681 tatacttata aagttcagcc agctaatgta atttctgtat catttcaaga taatgttact
     1741 ggatatttag caggacttat tgcaggtaaa atgactgata ctgggaaagt cggttttata
     1801 ggaggagttg agggttctag tagagataag tatgaatctg gatttagaaa ggggcttaaa
     1861 acttcaaata aagatgctga gttactagtt aagtattcaa atatatttga aaaccctgaa
     1921 tcagctagaa ctattgcaaa ggaaatgaga gattctgata gagatgttgt attttcagct
     1981 acagaagatg atagtaaaag agctattcag gtagcaagag aaaatggtgg taaagttata
     2041 gctattaata aagaccaata cgatatggct ccagataatg taataagttc aattataaaa
     2101 gatgtagaac aacctgtcta tgaactgata aagaatgttg caaaagatgg ttttaaggga
     2161 agtaaagtaa tggaatttaa aataaaagat ggagaacttg gcttgacttc aaagagcagt
     2221 agaaatatac caccagatgt tttggaatac ataaaaaaag agtataacaa agtgaaagat
     2281 acatattaat tattgatgta gaagattata aaaatatact gcttaagttt agattagcaa
     2341 taaaaagata tatttattaa atttgtgcta actgtacaaa atatattgat taagtttaga
     2401 ttagtgataa aaagatatat ttattaaatt tgtgttaaca gtatggaata tactgcttaa
     2461 gtttagattg gtgataaaag gatatattta ttaaatttag tctaactgta caaaatatat
     2521 tgattgagtt tagattagca ataaaaagat atatttatta aatttgtgct aactgtacgg
     2581 aatatactgc ttaagtttag attagtgata aaaagatata tttattaaat ttgaaccaac
     2641 tgtacaaagc tatactaatt aagcttagat tagctatata aaattataac aataagtgtg
     2701 tgggcagaaa aattctgcta cacactttat ttatattcac ataaaaaatt tatcaaaaaa
     2761 aagaaaaagg agtaaaaaat ggaatttaca agagaaccat ttatactaga tgacgatttg
     2821 tgtctagctt tggtggacaa aagaattagt tatctaatgg aaaatgaatt aaaattaaga
     2881 aatatagaga taataaaaac aatagaatgt aaagaattat atgaaagcat aaaatatcac
     2941 ccggatatat gtatttgtaa tttaggaaaa ggagatataa ttgttgcgcc gaatgtatat
     3001 aatcaataca aagagttatt aagtagatat aaatttaata taattaaggg agaagctaat
     3061 ttattaaata gataccctta tgatatacct tacaatattg cgatagttgg tgactatgct
     3121 atacacaatt ttaagtatac tgacaaagca atattagatt atattgaaaa taataaactt
     3181 aaaaagataa atatagagca gggctattct aaatgctcaa tctgtatagt agatagaacg
     3241 tctataataa catcagataa aggtatttgg aaaagtatga agaatacaga aatagagtgt
     3301 ttattgatag aaaaaggtca cataaattta tttgagatga attatggatt tataggtgga
     3361 tgtacagggt tgatttctaa ggataaacta gctttttgtg gagatgttaa aaaacatcct
     3421 gactatgaac gtataaaaag ttttgtagaa agtaaaaaca aggagatagt tacacttagc
     3481 tgtgaaaatt tactagatat aggttctata gttcctctca tgacaagaaa ggagcgataa
     3541 ctttggttga gaaggataat atttcttcca tgaaattttt gaggaataat aatgtaaacg
     3601 atagattaat atatacgaat gacattgtag aagtagtgat agattctgca aagcaagaag
     3661 tgttaaataa aaaaatactt aatggtacta aagctgaaca aagagcttta aatattgatg
     3721 agatatcaac ggaaataact agtatgataa taagtataat gaaagagaaa cttttgaaag
     3781 aatacattct aaaatgctat gggcgtacat atcctgaaga taaaaataat atatacatat
     3841 attcactgaa catatttgct aaaaaagaga tttttatgag agaaacagta tttactaggg
     3901 tgagaaatta tatagaagaa aatgatttta taaatgtaga aggttttatt agatttagaa
     3961 tgagagaatt tatgaaatat atttctgcta taggtgatat tgcagttgag gagtatttaa
     4021 taaagaaaga ccaagatgaa tttataagag ttttaaaata ctttatagat actcaagaag
     4081 aaaagattga tttgcttaaa gttcatataa tggaagataa tacatttgtt ttatacgata
     4141 aaaatggaaa taagatagac agtatagatg atgaagaaat tataaatatg gtaataagag
     4201 aaaatttaaa ttatgaggac tttttaataa gtaccttatt aactctatgt cccaaaaaaa
     4261 tagaaatatt ggatttgtta aataataatt gctcaaagga aattatagat actgtagaag
     4321 caatttttga aaataaagtt agtataatta tggaaaacta gaatctaagc atataaaagc
     4381 tatccatata aaattaaaaa aattcttttt aaatcgacac aaaagactta taattgtata
     4441 taaagctata gtataactag agttattaag tataaagaat atctacttga ttaatgcaat
     4501 atagctggca aatatacaat tgataaggag taattttata atggataatt taattaggat
     4561 actgatatta gctgttattg gtggatttat aggttatgtt acgaatgtag ttgctataag
     4621 actgatattt agaccaatag agcctattaa aatacctatt ttaaatatag aaatagtagg
     4681 tcttatacca aagagaagag cagaaatagc agcaaatgta ggagaaataa ttcaagaaga
     4741 atttctttct atggacgaaa tacttgcaaa tatcattact gacgaagata aggaagaagt
     4801 tgtaagatac ataaaagcaa gggtaaaaat tataatacat gagaaagttt catttatccc
     4861 gagtggtata aaaaacatga tacaagatta tctaggagag ataattgagt ctgaagttaa
     4921 gcaaagtata gatgaattga gtaaaaatat aataaataaa gcaaatgaac gtatagatat
     4981 acaaaaaatg gtcgaagata agattaatga actagattta tatgaattgg aagagataat
     5041 aataagaata gctaagaaag aattaaaaca tatagagttt ttggggcttg tcttagggtt
     5101 tttaataggt atagctcaag ggttaattac tatgtttatt taaatatatg agaagtagca
     5161 tttatttaag tactaattat atttacctat ttgagtgaat tacttattaa taacatttag
     5221 atattaattg tatttaccta tttgagtgaa ttacttatta atagcattta gatattaatt
     5281 gtatttacct atttgagtga attacttatt aatagtattt agatattaat tgtatttacc
     5341 tatttgagtg aattacttat taatagcatt tagatattaa ttgtatttat ttatttgatt
     5401 gtgttactta ttaatagtat ttaagtattt actgtactac ttattaacta tattaagtat
     5461 tgattgtatt taagtataca aaacctaaaa agagtacaaa aattagaagt tagttttaat
     5521 aaaaattagt tttagtattt atctagtcat atctatcatg catgtggata cgttttaaaa
     5581 attttaaatt tatgaaaata ttataatatc actataaatc aagagattaa tttaatataa
     5641 aaatataaga atattggttt acagctgatt gagatgaaaa ataatgggta attaatatat
     5701 tacattaatg ttgattgatg tataactatc tgttataatg aaaatatatt aaaaatcata
     5761 gtgttgaaga ggaagagtag agtagaaacc attctcagag aatttgggtc tatggctgag
     5821 agcccatgta ataggtctat ttgaaaacta ccttggagct gagtttatta gcagtatttg
     5881 tatttgtact atacgtgaaa gtgctcgggt gacgacctta tagtcatcaa gagggttgta
     5941 tatacttgta tacgccaact tgggtggaac cgcgaattaa tatcgtccca aacatatttg
     6001 gggcgatttt ttattacaaa aaatctaaaa attatttcaa taaggaggaa aaaacaatga
     6061 ttaaagttgc tttaaaagat ggctcaataa aagaatttga aaatgctatt tctgttatgg
     6121 atgtagctaa atccattagt gaaggattag ctagaaatgt ggtagcagcg tctgtgaacg
     6181 gagaggttgt aggtctggac cacattatag atactgattg tgacttgaat ttatttaagt
     6241 ttgaagataa agaaggtaag gaagttttta gacatacatc agcacatata ttagctcaag
     6301 ctataaaaag actttaccca gaagcaaagc ttgctatagg accaagtata gaaaatggat
     6361 tctactatga tatagattta gaccatagat tagttccaga ggacctagag aaaatagaag
     6421 ctgaaatgaa aaaaatagct aaagaagatt taaaaataga aagatttgaa cttcctagaa
     6481 atgaagcttt agagcttatg aaagaacaag gagaagacta taaggtagaa cttatatctg
     6541 atttacctga aagtgaaata atatctttct acaagcaagg tgattttact gatttatgta
     6601 gaggaccaca tttaccatct actaaaaagg taaaagctgt taaattacaa agtgtagcag
     6661 gtgcatattg gcgtggtgac gaaaataata agatgcttca aaggatatat ggaacttctt
     6721 ttgagaaaaa caaagactta gaagagtact tacatttact agaagaagct aaaaagagag
     6781 accacagaaa attaggtaaa gaattaggat tatttatgat acctgaagaa ggtccaggat
     6841 tccctatgtt tttaccaaaa ggtatggaac ttaaaaatga attattaaaa ttctggagag
     6901 aaatacacag aaaagctgga tatattgaga tagaatctcc aatcatatta aatagaaaat
     6961 tatgggagac ttcaggacac tggtatcatt acaaagaaaa tatgtataca gttaaaatag
     7021 atgatgagga ttatgctata aaacctatga actgtcctgg tggattaatt tattataact
     7081 ctcaactaca ttcatataga gatttcccaa tgagagttgc agagcttggt agagttcata
     7141 gacatgagtt atctggtgca ttacaaggat taatgagagt tagagcattt actcaagacg
     7201 attcacatat attcatgtta ccagagcaaa ttaaggacga aataaaagga gtagctaact
     7261 taatagatgg tatatacaaa acttttggat ttgaatataa tttagaatta tctacaagac
     7321 cagagaactc tatgggaagc gacgaagagt gggaagcagc agaaaatgga ttaagagaag
     7381 ctttagaaga gttaggtcta ccatatacta ttaatgaggg tgatggagca ttctatggtc
     7441 ctaagataga cttccatcta aaagattgtt taggaagaac ttggcaatgt ggtactatcc
     7501 aattagatat gcaacttcca agacaatttg ataatactta tattggtcaa gatggtgaaa
     7561 agcatagacc agttatgatt catagggttg cttttggtag tatagaaaga tttataggta
     7621 tattaataga gcattatgct ggtaaattcc cagtttggtt atctccaact caagttaaga
     7681 tacttcctat atctgataaa tttatggatt atgcaaatga agttaagaaa gagttatttg
     7741 ataagggtat aagagttgaa ttagatgata gagctgaaaa aattggattt aagataagag
     7801 aagctcagct tgaaaaagtg ccatacatgc taatagtagg tgaaaaagaa gtagctgata
     7861 ataatgtttc tgttagatca agagataaag gtgaaatagg tagtattaaa ttagatgaat
     7921 ttatagctag tatttcaaaa gaaattgaat caagagaaag tattattcaa gactaatata
     7981 tattatatta gtagctaaga tattgttata taagataagt ttaatcaata tgttgatatg
     8041 ttgatgcata gtgattaaat ttatgaaaag atgagtataa ttagaggtac agttaatcat
     8101 atttttatga ttaatgtacc tctagttttt tgtatggtag atttattaat aaatatatca
     8161 tagaagtgtt ttgaacatgg aaatatttat gtgcattctt taaataaaag tttatttttt
     8221 gagtgataat taagtgcttg ttggtaaggt tatggctgta aaaatcataa ctttattttc
     8281 atatttgttc cattttcata aaaattatta tccctttaag aaaatttctt aatcctcttg
     8341 aaatatttcc tttttagtct aaagttaaat ttctttcttc aaaatgaata tttaaatgaa
     8401 ctaaaattta agtacatttt ctaatcttat gagtctattt ttcatagata attgccctat
     8461 aatagaagaa tctatgttgg agctatgtgg tgacaataac agcattgtca gtgattaatt
     8521 aatgctttat aaatgattaa ttagtgtttt atgttatttt tggacttacc ctctatacat
     8581 agattaattt atttaacttt agatatagag agaatgtcaa gtacatacac agacattaga
     8641 gtttaagaaa gtgtttatgg agcaagaact tttaaaagag gtagtgactt agtttaattt
     8701 caagaaatga taaatacaaa agaggaaaaa gagaggtgtt gaaatgatag aaaaagtaga
     8761 agaaaaatct aagattatta aaacatcaaa agaatataag cgaactataa ttgaagaaaa
     8821 agataaagaa tggaccaaaa aattaaatga tatacttagt agaagtagtt tttctaatga
     8881 tgaattagat aaaatcaagg cgttaattcc aaaagagatt ttgactaatg aaaatgttgg
     8941 agaagttgtg actgaagatg gatatgctaa gcctgagtat gatgaggtat ttaaatcatt
     9001 gttcacttta aataatgaat atgatttact tgtaaatttt ataaatgata tcctaaaaga
     9061 tgctccatat gctaacagga atatcaaacc gttcactcaa ataaagagaa taattagagt
     9121 tgaaactgac ccaacaatta attacattgg agagaaaaga cctagacttg atattttggc
     9181 tgaagatgaa gaaaataatc atataaatat tgagatgcaa agagcttttg agaacgatta
     9241 tttggaaaga gctgaatatt atcttagtcg tgtacatggt agaaagttag aagaaggtaa
     9301 agagtataaa gaaattggaa aaactattgg aatacatata ctaaatcatg taaaatataa
     9361 tcacatagaa gattatgtaa attgcctgag attaacaatg gacgggcatc cagatattta
     9421 ttctagtaaa actgcattat attttataga gcttccaaaa attcataaat ctgactatat
     9481 agtaaataga attatgctat ggggaaaact tattagtaat ccttctagct tagatgtaag
     9541 agttatagct aagaatgatt ctattattaa aaaagcactt gatagattaa aagaattagg
     9601 tagcaatgaa gaatatttat taaatctgaa aagaggtgct tatatcatga ataaaagtag
     9661 aaattttaaa gaagagattg aaagagagac agcaattaga gttgcaaaag aaaaagatta
     9721 taaaataatt ataatgttga aaaaaaatgg ttttaaatta gatgacatat taaataaatt
     9781 taatgatttt gacttaagtg aagatgagat aaaagaagta tatgaaaata attgatgata
     9841 aaaagtgaac ttatataagt ttgctgaatc ggagtctgga aatatttatg tgtatttttt
     9901 aatgaataaa aatttatttt aaaaacaata atttagaggt acagttaatt atatttttat
     9961 gatactgtac ttctagtttt ttctattgta gatttattat ttactaataa atctacaata
    10021 gaagtgcttt tgttgtaaga atcattttat ctaatgattg ttttttataa tagttaaatt
    10081 tccatttgta gtgtttaaat ataaatctat aacagcattt ctataaatgt tataaatcac
    10141 tataatgatt caactcaaag ttactgctta aagaagcaga gattttatca aggtatatca
    10201 tggaaaaaaa tattttattg taatatttat aagattttat tatggaaata atgtaaaaac
    10261 tttataaata atatatttta tacctagtta tagataaatt tatatagtta ttattaaaaa
    10321 aagcaataaa aagtttaatt caatttagca aatttagtga tataattaaa aaagaaaaga
    10381 aatatggact tatttggaat aattttgaca atctatttac tacacgtgta gagtcgtata
    10441 taattaaatt atacataaaa tataaaaaaa taatttagta atacgttagg agaaagtatt
    10501 atgataaagt caagcttatt ttggaatatt ttcattgcga tatcctttat gatagaatgg
    10561 tttctttgta agaaaatgct agattataca agtgagaaaa ggatttctaa caaaaaaata
    10621 aacttttgta tggtaggtat tattgttttt gctgacataa tatatttttt tgatgtacct
    10681 ccaaatataa gagtaattat atctatgata attactattg cattttataa aatctcatat
    10741 gatgtggggt ttataaagtc tgtattaata tccttaattt attggatgtt actaatcgcc
    10801 acagatgctt tgagtatatc tttaacagtt tggcttaatt ctataaatga catgagtagt
    10861 atggggacgg gagatatata cagaattgag tctataatat tgggaaagat acttttgatt
    10921 gtgtctttgc ttttatatag agccttaaag ataaaactta atatagaaat aaataaaagg
    10981 acattatttt atatagttat tcctatagtc gctaatatag catctttttt tgtaattttt
    11041 gaatacatat ttaatccagg gtctggtagc ttaatacata atttccaatt cgttatgatt
    11101 tctgttgtat tgcttatatc aagtatcact ttagttttaa ttgctaaaaa attacagcaa
    11161 tataatactt tagttgtaga aaacaatatg attaaaaata ctttgaagta tgaaaatgag
    11221 tattatgaag atatagaaaa gaaatattta aaaactagat tactaagtca tgatatgaaa
    11281 aatcacatat tgtgtataaa tgctatgatt aaaaaaggta ttgatgttac ttcttattta
    11341 aataatttgc aggtagaaat tcagagtaat gacttgttat ttaatactgg taattttata
    11401 ttagatgcta tattaagtga aaagaaagag gtttgtgata agaatgatat agaactaaaa
    11461 ataggaataa attttagttg ttgtgaagct gttgaattag tggatatatg tcatatattt
    11521 tcaaatattt tagacaatgc aattgaggca tgtaataaaa ttgatagtgg aaatagagtt
    11581 atttgtgtta aaggtgatgt tatgcaaaat ttttatttaa taagagttga aaatactaag
    11641 atgaataaga ttattactaa aaatggagat attttgacag acaaaaaagg ttctcttcat
    11701 ggacttggaa taaaaagtgt aaaaaactct gtaaataagt atggtggtaa tgttgtaatt
    11761 gaatatgatg ataaaaaatt tgtagttaaa attgctattc cacttagaaa tgtgaagaaa
    11821 gcagttaatc atgtgattta aatgtatata aatttgatgt gtagaaattt aatatataag
    11881 aattaatgta taaaagtgat gcatagaagt ttaatatata agaattaatg tataaaagtg
    11941 atgtatagaa gtttaatata taagaattaa tgtataaaag tgatgtatag aagtttaata
    12001 tataagaatt taatatgtat aaaagtgatg cataaaagtt taatatata
//
LOCUS       DAEPUT010000114        11843 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.117, whole genome shotgun sequence.
ACCESSION   DAEPUT010000114 DAEPUT010000000
VERSION     DAEPUT010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11843
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.117"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            202..1242
                     /locus_tag="KRL22_003451"
     CDS             202..1242
                     /locus_tag="KRL22_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1273889.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            1597..2919
                     /locus_tag="KRL22_003452"
     CDS             1597..2919
                     /locus_tag="KRL22_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH1273890.1"
                     /translation="MFDIDGRPPILKCLQLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGTFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIIKFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            3216..4577
                     /locus_tag="KRL22_003453"
     CDS             3216..4577
                     /locus_tag="KRL22_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH1273891.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            4650..6044
                     /locus_tag="KRL22_003454"
     CDS             4650..6044
                     /locus_tag="KRL22_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1273892.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            6106..6576
                     /locus_tag="KRL22_003455"
     CDS             6106..6576
                     /locus_tag="KRL22_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HBH1273893.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            6579..8795
                     /locus_tag="KRL22_003456"
     CDS             6579..8795
                     /locus_tag="KRL22_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1273894.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETTEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            8878..9549
                     /locus_tag="KRL22_003457"
     CDS             8878..9549
                     /locus_tag="KRL22_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1273895.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            9912..11126
                     /gene="dpaL"
                     /locus_tag="KRL22_003458"
     CDS             9912..11126
                     /gene="dpaL"
                     /locus_tag="KRL22_003458"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH1273896.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            11253..>11843
                     /locus_tag="KRL22_003459"
     CDS             11253..>11843
                     /locus_tag="KRL22_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1273897.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT         4476 a         1356 c         2404 g         3607 t
ORIGIN      
        1 tgtaattgct tatttaatag agcatttttg taaaatgaag aaagtatatc tatcaaatta
       61 aaactaagta gatatacttt ttattaagtt ttgttttaaa ataatattat taaattataa
      121 ctaagctttt ctgttatgat ataattaaat agataatgtg aatgattatt atatagaata
      181 cttatttgga gttgatattt tatggacaaa cacagtgatt cagtaatgta tggtggaatg
      241 gaagtatata atatttgggg aacaacaaca gtagactcca taattggaga gtctgatgta
      301 atgcgtgctc ttaagaatag aatttgtaaa attggaaata gtgattctac tgtagctata
      361 actggagaaa gtggcactgg aaaagaatta atagcaagag ccattcatct cgcaggaaac
      421 agagggaata aaacattcgt tgctataaac tgtgctgcta taccagaacc tttactagaa
      481 agtgaacttt ttggatatac aaaaggagct tttagtggag cagattcaaa aggtaaaatt
      541 ggtaagtttg aattggccaa tggaggggtt gtatttttag atgagatagg agatatgcca
      601 attcaactac aatcaaagtt attgagggta ttacaggaaa agaagtttac gagaataggt
      661 tcaaatgaac taattgatat agatgttaga atcatatcag ctactaatag agatttattt
      721 gagttggtta aggaaaataa atttagagaa gacttatact atagattgaa tgtaatacct
      781 ttagaagtgc ctccacttag agaaagagga gacgatatac aaatattaat aaacaatttt
      841 atagacaaat attcgagaaa gatgaagaaa aacgtgtacc atatagagcc agatgtggaa
      901 caaatgttgc ttaagtatcc ttggccagga aatattagag agttggaaaa tactatagaa
      961 ctggcattaa accttcttga ggaagatgga ataatacata aaggaataat aaatagaaag
     1021 atacttgaat attttaagtt aaataatata aatataaagt tacttgagga aagtgactat
     1081 gagataagta tggaacaaga catacttaca cttgaagagt ttgaaagagc ctatataaag
     1141 aaagtgttaa agttttacgg aaatgatact aagtctaaaa aactggctgc caaaaaactt
     1201 ggaatatcac tagctacatt gtacagaaaa atagatgtat aataattagg ctttttattc
     1261 tcaattctaa aatttgaaat tataaaattg ataaaaaaca cttggaaaac tattttctaa
     1321 gtgttttttt gtgtaatagc attttattat ccaaaaataa aaaaaattta aaagaattta
     1381 aaaaaataaa tgctttaata aattatcaaa tactaacaaa tataataaaa attatatatg
     1441 taaaacaatt atgttaaaaa attggcatta taattgcttc atattaagtt gagatgacaa
     1501 aataaaaaaa gaaaggatgt tgtgtgagat aataataact gtcattaaaa atagttggga
     1561 gtgataacct tgagtaaata tcaaaagaat gtttctatgt ttgatattga tggaaggcca
     1621 ccaattttaa agtgtttgca actatcaatg caacatatac tagcaatgat agttggaact
     1681 gttacagtac ctatagtcgt aggaggagct gtgggtgtta gccctacaca aataacactt
     1741 ttagtgcaat atgcattaat aatagctggt atatcaacac ttatacaact atatccaata
     1801 ggaaatattg gttcaagatt gcctataatt tttggagttg gttttactta tgtaccaaca
     1861 cttgtagcag tcggaggaaa ttatggatta gcaagcattt tgggtgcaca attaataggg
     1921 ggagtggcta cagtattaat agggacattc ataaaaaaga taagaaaatt ttttccgaat
     1981 atagttgcag gaacagtggt ttttacaatt ggattatctt tgtatcctat agcaataaat
     2041 tatatggcag gtggtgtaaa tagtcctact tatgcctcta tgcaaaactg ggcagtagcg
     2101 gctataacat tagtggtagt tataggtctt agtcaatttg caaaaggata tgcaaaattg
     2161 gcagcaatat ttttgggaat tatagttgga tattgtgtat ctttagttct gggtataata
     2221 aaatttgacc ctattagaga ggcaacttgg tttgcgatac ctaaaccgct tgaatttggg
     2281 atggaatttg atatgcctgt aataatctca gtagtaattg taagtataat caatgctgtt
     2341 caagcaattg gagatttatc agctactaca atgggaggca tggataggaa tatcacagat
     2401 aaggaattat caagtggagt aataggaagt ggaatttgta ctatgatagg agctttgttt
     2461 ggaggtttac caccatcatc atatagccaa aacgtgggga tggtagctat gaacaaagta
     2521 ataagtagat ttgtgcttgg aatagctggt atatttatgt tattgtcggg gtttgtgcct
     2581 aaatttggtg cattaatgac tactatacca tattctgttt taggaggagc tacaatatct
     2641 atatttagta tgataacaat gacaggtata aagttaatta ttacagaaga gttgtcatca
     2701 agaaatatta ccattgttgg tttggcaatt gccttaggca tgggaataac atcagtacca
     2761 gcagcccaag aggcatttcc ttcatttgta aagttagtat ttggagaatc tccaatagta
     2821 attgcaacat tggttgcatt cgttttaaat ctaataatac caaataaaag tctagaggat
     2881 gaggctaaag aaagagctgt tatggaagag actaattaag atataataat ttaaaagaat
     2941 tgtttaaatt atttagcatg agattgttag attatttttg atagctattc attttaataa
     3001 aaaatttaac aaataaatat ataccaggta attaatgttc atttaagttg aaaatcgggg
     3061 agggaatatt tagaaatttg ttaatttttt ataaaaatag ctcagtttag ctgtgtttat
     3121 cggttgagca ataaattcat ggtcataaaa atatttatag aaaataatta taaaaatatt
     3181 tagtcaagat atttatgtat gggaggattt attttatgaa aacacgtaat acttcaaaat
     3241 atgatgtcga tgggatacca ccactaaagg aatcaatacc tttggcctta caacatctgt
     3301 tagcaatgat agtaggaaat atggtacctg cgatattaat agcaaacgtg gtaggactta
     3361 accaggggca agcaacaatg ttgattcagg gttctatgtt agcagcaggt ttagcaacgt
     3421 ttttacagtt atatccaata cctttattta aaggatttaa gttaggttca agattacctg
     3481 taatgatggg aatgagttat gtatttttag gagcttgtct ttcagtagca gctaaagatg
     3541 gtttagcagc tctatttgga gcacagattg ctgctggggt aatcgtattc tttgtaggat
     3601 ttggagttaa gaaaattaga catatattca ctccaatagt ttctggaact ataatagcat
     3661 gtatgggact tggactattc gcaacagcta taaagaattt agctggagga gaaggcacac
     3721 aaacatttgg aagcccaata aacttcacag taggagttat agttgctttt gtaataataa
     3781 tgataaataa atatggtaaa ggtttagtaa aaaattcttc aatattaata ggaatattag
     3841 taggttatgc tatatcttta gttttaggat tggttgattt ctcagccgtt caaggagcag
     3901 ctatagtatc tttaccaaca ccagcagctt ttggattaga atttagacca gagttaatag
     3961 taatgtttac tattatttac ataataggta tagctgatat gatgggtgcc tgtacaatag
     4021 ctacagtagg agcaatggat agagaggtaa ctgacgaaga attagcatca gttgttttag
     4081 gaaattctat aacttctata atttcatcac tatttgcagc tcttccaact ggagtattta
     4141 gccaaaatac agtaattgta tctatgaaca aagttacaag tagatttgta atagcactag
     4201 gggcacttgt attattacta gcagggatat ctccagcatt gggtgcaata atgacaacta
     4261 taccatcttg tgttgttggt ggagcaactt tagtagtttt ctcatcaata gcaatgtctg
     4321 gtttctctat tatgagtatg gatggattca ctgaagaaaa caatcttata gcaggtgtat
     4381 ctatagcaac aagtatgggt cttacaactg ctccacaagt tttagaccaa ttcccagaga
     4441 caattggaac tgtccttgga gggtcaagta tagtttctgg agcaataata gctatattac
     4501 ttcaaacatt atttaaatta aagtcacgta aaagtgctga aaacgttact tcaaatcttg
     4561 aggaaaatat tggataaatg tattagatat aatatgagaa aaccatatgg taaaatgttg
     4621 taatgaaagt attcaaaggg ggatttaaga tgattgatat actaataaaa aatgcaataa
     4681 ttgttacagt taataaagac agagatgtta tatttgatgg agcaatagct attcaaggtg
     4741 acagaatctt ggacatagga aatacagttg atattgagcc taagtatctt gatgctaaaa
     4801 aagttataga tgctaatgga aaagtaatat tccctggctt tataaatact cataatcacc
     4861 tgttccaagt gttattaaaa ggtttaggtg atgatatggc acttcatgag tggttaaata
     4921 caatgatgtt tccatcagca aaattcttaa cagaacaaga tacttatgat gctgcaatgc
     4981 ttggatgtat ggaaggttta aaaagtggta taactacaat ggttgattat atgcatactc
     5041 acaatagacc aggacttaca gatggaatag taaaggcata taaagattta ggtataagag
     5101 gggttgtagg tagaggttgt atagatttag gtattcacaa agagcttata gaagatgtgg
     5161 aaacggttga aaaagatttg agaagggtat tcgaaaaata tcataattca gaaaatggaa
     5221 gaataaaaat ctgtgtagct ccttcttcaa tgtgggctat atctgaagaa atgggtaaga
     5281 tgctttggaa tatagttaaa gaatatgatt catattttac agttcatata tctgaaacag
     5341 aatttgcaag aacagcaaca aaggatatac atggagaaat agatataaaa ttacttgaaa
     5401 aatggggtat agtaggtcca gaagttgtag cagtacattg tgtatgtata actgatgaag
     5461 acatggaaat gcttaaaaag tatgacataa aagtttctca taatgtagca agtaacatgt
     5521 atcttgcttc tggtgttgca cctgtgccag aaatgttaaa aaaaggtata aatgtgagtt
     5581 taggtcttga cggtgcagca agtaataacg cacaagatat ggtagagctt atgaaactaa
     5641 cagctttaca acacaaagta aataattgtg accctctggc aatttctgca gagaaagttc
     5701 ttgaaatggc tacaattgag ggagcaagaa ctcttagaat ggaagatgaa ataggttctt
     5761 tggagattgg gaaaaaagct gacctagtaa tatttaactc aatgctttct ccaaaatcaa
     5821 tacctcttca caatcctgta tcaactttgg tatactcagc tagtatgcac aatgtagaga
     5881 gtgttttagt tgatggaaat gtaatacttg aaaatggaaa agtaactaca attgaaagtg
     5941 aagaacaagt gttgcttaat gcacaacatg cagcagaaga attatgtaag agagctaatg
     6001 taactaatag aatggaagga cataagtgga atagcttata ctaatattaa aataagattg
     6061 taataatatt ctattacaac attagtttat ctgtaggagg agaaaatgga aaaaataaaa
     6121 ttaaatatta atgattacat gtatgaaata gaagttgaaa agaatgaaac tcttttgcat
     6181 gtacttcgtg aaaaattaaa tctaactgga gcgaaacaag gttgtaatag tggcagttgt
     6241 ggagcatgta aagttttgat agatggagtt gacatgaaat cttgtaaact tcttgcaaaa
     6301 aactgcgaag gtaaagttat atacactata gaaagttttg ctaatggaga aaatcttcat
     6361 ccaatacaag aagcttttat agaagttgga gctgtacaat gtggatattg tactcctggt
     6421 atgattataa caacacaagc tcttttaaat agaaatgcat ctcctaatga agatgaaatt
     6481 agagaagctt ttaaagaaaa tctctgtaga tgcacaggat atgtaaagat tatagaagct
     6541 gtaaaattat ctgcagctag attagggggt agataattat ggaaaaggta ataggaaaat
     6601 cataccctct aaaagatgca gctttaaaag ttactggtca aatgaaatac gtggctgata
     6661 tgaaaccaca aaatgtactt tacgctaaga tgcttttaag tcctgtagca catgcaaaaa
     6721 taaaaagtat agatacaagt gaagctgaga aagtagtagg tgttagagct atagctactt
     6781 atctcaatac atcacaaaga aaatacaatg gttcattaag attttatgag cacaaaatac
     6841 ctgaaaatga agttatattt tcagatacag ttagatttgt tggtgaccgt gttgcagcag
     6901 tagccgcaga gactacagaa atagcagaga aagctgtaaa acttataaaa gttgaatatg
     6961 aagaattgcc agctgtattt actatacaag atgcaataaa agaagatgct atctgcatac
     7021 atggagattc aaatatagtt tctcaaaaca acataaatgg gggagatgta gaaaaaggct
     7081 tcaaggaatg tgactatata tttgaagatg aatactctac tccagcaata catcatagtg
     7141 caatagagac tcatagtgta attgcacact atgattataa tgataaatta actgtacata
     7201 caccttgcca aaatacattt ggatttagaa taatactatc tcaaattttt gggatgtcat
     7261 taaataaagt aagagttata agacctgcta ttggaggctc atttggtgga aaattagaac
     7321 ttacaattga accagtagca gccgcattat caaaaatgac aagaagacca gttaaaatgg
     7381 ttcttacaag aaaagaatct atgatatcga caagaactcg tcatgggtct tttgtaaaat
     7441 taaaaactgg tgtaaataaa gatggtgaag taatagcaca agatataaaa atatatacaa
     7501 atacaggagc atatgcatca agtgctttaa atgttatagg agcacttagt cataaagtat
     7561 ttaaagttta taaaatacca aatataaagt ttactgggat gcctgtatat acaaatacac
     7621 caatagcagg agctatgaga ggctatgggt cacctcaaat atttatggct caacaagctc
     7681 aatttgcgaa aatagcaaag gaaataggta tggatttagt cgattttcaa aataaaaatg
     7741 cagtagagcc agatgatgtc gatataatct tccacggttc tcttggaaat cctagagtat
     7801 tggattgtat agagcaaggt aagaagatgt ttaagtggga tgaaaagaaa aaacttccaa
     7861 aagaagaagg aaaatattta agaggtatag gtatggcaat aggtgcacat ggtaatggag
     7921 tttttggtgc acatagagat gttgttacat tgactcttaa attaaatgaa gatggtacgt
     7981 tgacactact aacaggagct catgatatgg gtaatggtgt tgtaactatg caaacaatga
     8041 tggtagctga agttttagga ataacacctg ataaagttga tacatttgaa actgatacgg
     8101 atgcatgtac attcaacctt ggtgactatg caagtagagg ggtatttgta gaaggtggag
     8161 gagctaaaaa gacagcagag aaattgaaaa atcttatatt agaagaagca gaaaaattac
     8221 ttgaaacatc aaaagaagat ttatatctag acaatggatg tgtaattagt aaacttgatg
     8281 aaaatgtaaa agcatcactt tctgatgtcg cagtatatag tcaaagtaaa tcattaagag
     8341 agttaactgt tgttgaagat tattcttcac cagctggacg tacttcttat ggtgtacatt
     8401 ttgctgaagt tttagtagat aaagaaacta aggatataaa agtagttgat tttgtagctg
     8461 tacatgatgt tggtagagtt ataaatcctc taaatttaga aggacaatta gaaggtggga
     8521 ttcatatggg tctaggatac gcattgagtg aagaattggc atttgatgaa caaggtagac
     8581 ctaaagctac tgattttaaa acatataaat tatttagaac tgtagatatg ccaaaatgtc
     8641 aagttgcatt tgtagatggt tatgaaaaag ctgggccttt tggtggtaag agtattggag
     8701 aatgtgccgt tgtaccagtt gcgccagctg ttgcaaatgc agtatataat gcaactgatg
     8761 tagagataca ttcattacca ataaaattaa aatagtataa attaaagcag aaataacaat
     8821 ttattgtatt tgtaaataga taataaaaat agatttattt ggtgaggaga tattattatg
     8881 gcaaagatat taggtatttg tggaagtcca cgtaaaggag caacagaata tgcagtgtta
     8941 gaagctttga aagaagcaga aactatacct ggtatagaaa ctgagtattg gtcagttaga
     9001 gggaaaaaaa taagtccttg tgtacattgt gatgcatgta taagaaaaga aactatgtgt
     9061 attataaaag atgatatcca agaattagag caaaaaatat tggaggcaga tggaattata
     9121 gtaggttctc cagtttatga tatgaatata actgctcaac ttacagcagt atttaataga
     9181 cttcgtccaa tgtatttagt tcatccagga aaacttcaaa ataaggttgg tgcagctata
     9241 actactggtg gaactagata tggtggccaa gaattgacaa aacttcctat aataaatttc
     9301 ttcctaatgc atgaaatgtt agtgtctgga ggtttaggtg gatgctatat aggtggtaca
     9361 atatggagta aagatggaaa agcaaaaggt gcccaagagg atgagacagg tatggacaca
     9421 gtaaaaagac ttggaaaagg tgcagcagag gcagttatgg tttctaagtt tggtcttgaa
     9481 aaatggaatg tcgtaaaaga agaattagat gttaaaaaag atgaaaaatc acctcttaga
     9541 gaccactaaa gatttattat attattgaat atatacaaat agtgatgtaa tagattattg
     9601 catcactatt ttatgtttta atttagattt tatagatttt atattaaaaa atatagaaac
     9661 aaagtgtttt gagatttatt tttaaatttt aaaaatgaga attaaaaagt gagaagatag
     9721 aaaaggtttt ttagttatta aattctacat acattgtatg aactaaagat agaaaagaaa
     9781 aaataataaa agcattgcaa tttctatact aaagagtcat agaaaaatat ctagtatata
     9841 tttagtgttg gcatgttaat tgcttatata ttaaagtata aaaatttaac aataatttgg
     9901 aggtatttta gatgttaaaa gaaattaaat ggaaagtaaa taatttgcca aagggcgata
     9961 aggaaaattg tatcaaattt ttaaatgaag aagaaataac taaggttaga aattttcaca
    10021 aaagctttcc tcaatataaa gaaactccat tagcaaacct agaaggttta gcaaaaaaat
    10081 taggtgttgc aggagtatat gtaaaagatg aatcttatag atttggatta aatgcattta
    10141 aagtattagg tggttcttat tctatgggta gatacttagc tcaaagatta gatacagata
    10201 tatctgagtt agggtatgac aaattaactt caaaagaaat aaaagaaaaa ttaggagaaa
    10261 taactttctt tacagctaca gatggaaatc acggtagagg agttgcttgg acagctaata
    10321 aattaggtca aaaatctgtt gtattaatgc caaaaggttc ttctgaattt agattaaata
    10381 aaattaaagg agaaggtgca gatgctagta taacagactt aaactatgat gatgcagtaa
    10441 gattagctaa tgattatgca gaagctgatg accatggagt aatggttcaa gatacagcat
    10501 gggacggata tgaagaaata ccagcgtgga taatgcaagg atatggaact atggctcaag
    10561 aagctataga gcaattaaaa gaatatggag tagatagacc aacacacgta tttgttcaag
    10621 caggagttgg ttcacttgct ggtgcagttc aagggtatgt tgcttcaata tatgatgaat
    10681 gcccaataac agtagtagta gaggctgatg aagctgattg ttactataaa tcagcagaag
    10741 ctggagatgg aaaaccaaga tttgttggag gagatatgcc aactataatg gcagggcttg
    10801 cttgtggaga gccaaatact ataggatttg aagtattaaa aaatcatgca gcagcatttg
    10861 tttcagcacc agactgggtt tctgctaagg gtatgagaac attaggtaat cctttaaatg
    10921 gtgatgaaaa ggtaatttct ggagaatctg gagcagttac aactggtctt ttagtagcag
    10981 ctatggaaag agaagattta gcagatttaa gaaaagattt aaaattagat gaaaattcaa
    11041 gaatactttt aataagcaca gaaggagata ctgaccctga caaatataga agtatagttt
    11101 gggatggaga atatccaagt atataaggaa ttactaaaat gcaattatta gatattggtt
    11161 tacatattta gaagatatat aagttctaaa atttagaaaa tatataagta tataaaatac
    11221 atacattata aaaaatctag ggggataatg aaatgttaaa cgaacaaaga aaacaagaag
    11281 taactgaaat atgccaaaaa ttaattcaaa atcctagttc ttctggaaat gaagaaggtg
    11341 ttgtaaaagc aatagaagag tcttttgaaa aattaggttt tgatagttgg tcaagagata
    11401 gatatggaaa tatagtagga tgtataaaag gtaacaagcc aggtaagaaa atattatttg
    11461 atggacatat agatacagtt ccagttccag atgcaagtaa atggagtgtt cctccttttg
    11521 aaggaaaaat agttgatgga aagatatatg gtagaggaac ttctgacatg aaaggtcaat
    11581 atactgcaat gatgtctgct gtagcgtatt ttgctaaaga cactaataga gattttgctg
    11641 gagaactata tgtagcaggt gttgttcatg aagaaatatt tgaaggtgtt tcggctagag
    11701 agataagtaa ggctgttcaa cctgactatg ttgtaatagg tgagtcttca gagttaaact
    11761 taaagattgg tcagagaggt agaggagaaa tagtagtaga aacttttggt aaaccagctc
    11821 actctgctaa tccagaaaaa ggt
//
LOCUS       DAEPUT010000115        11235 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.119, whole genome shotgun sequence.
ACCESSION   DAEPUT010000115 DAEPUT010000000
VERSION     DAEPUT010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11235
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.119"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            47..304
                     /locus_tag="KRL22_003460"
     CDS             47..304
                     /locus_tag="KRL22_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273898.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(414..1094)
                     /locus_tag="KRL22_003461"
     CDS             complement(414..1094)
                     /locus_tag="KRL22_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH1273899.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            1354..1653
                     /locus_tag="KRL22_003462"
     CDS             1354..1653
                     /locus_tag="KRL22_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273900.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            1977..3632
                     /gene="ilvD"
                     /locus_tag="KRL22_003463"
     CDS             1977..3632
                     /gene="ilvD"
                     /locus_tag="KRL22_003463"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBH1273901.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            3976..4605
                     /locus_tag="KRL22_003464"
     CDS             3976..4605
                     /locus_tag="KRL22_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1273902.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFKQ"
     gene            4631..5443
                     /locus_tag="KRL22_003465"
     CDS             4631..5443
                     /locus_tag="KRL22_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1273903.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFTKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            5991..7082
                     /locus_tag="KRL22_003466"
                     /pseudo
     CDS             5991..7082
                     /locus_tag="KRL22_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
     gene            7081..7492
                     /locus_tag="KRL22_003467"
                     /pseudo
     CDS             7081..7492
                     /locus_tag="KRL22_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            7629..8282
                     /locus_tag="KRL22_003468"
     CDS             7629..8282
                     /locus_tag="KRL22_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1273904.1"
                     /translation="MNNIYSDIYEKLSTLQWIMKRHQMFCQAESGPFADTSRGQGRIL
                     AMLKIQPEIATKELAYLLGIRQQSLNELLNKMEKNGYVERKPSENDKRVMIVHLTEKG
                     KQVQQPKTDYQNIFNCLLPEELLQMSQYLDRIIEAFQLQNGNALEENNMIDWMAQARE
                     RMGDEHFEQLMSMRERAFGHMRPPKDIPGAERFSENYNGYVPDRDGFQPRNFKPDIK"
     gene            8371..9693
                     /locus_tag="KRL22_003469"
     CDS             8371..9693
                     /locus_tag="KRL22_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1273905.1"
                     /translation="MNQKNENYWLLDAPVTKAIWHMAIPMMLGMSINIIYNITDTFFI
                     GRLNDTAALATISLLLPFTTILMAIGNLFGTGGSTLFSRLLGSENTDRTKQCSATTLW
                     LSFLFGLLTAIISIIFSNYIIRLLGADSNTFAYVKQYLIFYGMGAPFIIANFTLEQLI
                     RGDGKSVESMIGMMISIGANIILDPILMFGLQLGIRGAAIATVIGNAFAVIYYIVCIQ
                     RADNQLSALPKYFRLEKQMLKEIFLVGLSAMLLDILLIVSSLMFNYYALKYGDYVLAG
                     FGISQKLVQIVDLIGMGLYMGVIPLIATAYGARNELRVKEIIKKTALYLALVITCLFT
                     ILFTCRNFIVHCFSNDSDVIRIGAYILTVQLCSSFFAAGAGLLTGIFQAKGEGTPAVV
                     MSVMRGIMLIPAIIFGNYLFKMNGVIFSLLVAEAISCITGLVLYKLKK"
     gene            9806..10017
                     /locus_tag="KRL22_003470"
                     /pseudo
     CDS             9806..10017
                     /locus_tag="KRL22_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10115..10474)
                     /locus_tag="KRL22_003471"
     CDS             complement(10115..10474)
                     /locus_tag="KRL22_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273906.1"
                     /translation="MRKKKDTHSFDFRPLGLAIREAREKAGLSRNDLGDKVFYGERHI
                     ADIENIGKHPSFHLFHDLVTMFNISVDEYFYPAKNVEKSTVSRQIDSSLDLLSDDELK
                     IIQGTIDGILNSRENKK"
BASE COUNT         4081 a         1597 c         2028 g         3529 t
ORIGIN      
        1 ttatttatta gaaattaaaa tgaattaagt aaatggagga attgatatga taataattag
       61 aagtcaagat aaaactaatt taatgcagat aaaccaaatt aaaatagatg gtagtcaagt
      121 ttatgcagta tttgaaagta aaattgatac tgtaaaaata ggagattatg aaaataatac
      181 aagagctata caagtgttgg acaatataca aaacttcatt gaaaatggaa caaaatatga
      241 ttatataaca tcaaataaag tcagatacaa tgttaataaa atatttcaga tgccagctaa
      301 atagtgagtg tgcattttaa tttaataact aaagcccact ttcttttgta gtatgaaaga
      361 gggctttaca tatttgtaaa tatcgaagta cacttatttt atcaataaat tatttaataa
      421 ggtataatgg accaattaaa caataaaaat tctcctaaaa cagcaagtat taaatatata
      481 atagcttcat ttttgtaaag agaggtaatt tttttgctta tgtcatcatc aattgtaata
      541 gcaatctcat cttgaataat atttttatat atagatggga aaatatcttt tttctttata
      601 agattaaata aattatttac acctacccat ataaaatatc ctaaaacagc acctaatgtg
      661 ttcatcatta aatcatcaat atctgtagct cttaagttaa acaattgaca aagttcaatt
      721 gctaatgaaa aacctaatcc agttaatgaa acattgataa tatttctaaa atttttccaa
      781 attaaaggta gtaaaaatcc taaaggcata aacataatta tatttaaaat atatgttaag
      841 atgccaactg agtcaaaagg tattagattt atttcatcaa ttctaaaaag cccactatac
      901 cttcctatat cccatatgct accaattcca gctttactaa gtgctagata gatatataat
      961 aaaaaaatat atacccatac taaatgtatc attacattct tttcaacttt caaatttttt
     1021 cgttttataa cgactatttg gtatattaag catggtaata taacgcaaat aaatgaataa
     1081 aatgtccata tcattttatt ttgtcccctt tcaaatttat gtttttagtt ttataagtac
     1141 tatctttata ttaaactgta agttttaaaa atcttttaat aaaatcttaa aaatttatta
     1201 atttataaaa atatattatt aagattaaaa aatatatata atcaaagttt ctacaattat
     1261 atagttaggg atataaaaat tttatcgtat gcataaatat tataaatata tggaaataat
     1321 aatagtatat tttggtaaag taggaggaat tttatgaaat ggattaaatg gtatagtatt
     1381 acatgcatat gtatttttat agtagtagct ttttatatgt ttatatttcc taataaaata
     1441 gaaactattg atacttcatc tgcatatagc tttgttgaaa agaaagtacc aaatagtgct
     1501 gtgtatcaag gatacaaaaa gaatccagtt gatggtacta ctacaattta ttacagctat
     1561 gataattcaa ctcatatagt tagattatca catccagaag actattcaag gaagattaat
     1621 tgggataaag tttcaaacat cagatttgat taatctttaa tatttataaa agtctatata
     1681 tctaaggcaa atatattatt aatcttattc atagttgagc actttctatt atagaagtgc
     1741 ctcttctgat ttatatcata aaatattact caacaatttg taaaatatat tagtttataa
     1801 aatatattga aaagataata ttatataata cgattgtgta agatattgat aaaaaatcgt
     1861 aataaatttt cattagtata tgctaatatt tttttacaat tttcgtaatt aattaataga
     1921 aaaatatatt ataataatat tatgaaaatt taaaaaagta agaaagaggt aatattatga
     1981 gaagtgatat aaaaaaagga atagaaggag ctccaaagag agcgttaatg tatggaatgg
     2041 gtcttactaa agaagaaatt gaaagaccat taataggtat agtaaatgca caaaatgagg
     2101 tgattcctgg tcatctgcat cttgatgaaa tagcagaagc tgcaaaaaat ggagtaagaa
     2161 tgagtggtgg tttgccatta gaatttcctg ctataggggt atgtgatggt atagctatgg
     2221 ggcatgtcgg aatgaattat tccctggctt caagagaatt aatagcagat tcaatagaag
     2281 ctatggctat ggcacatggt tttgatgctt tggtacttat acctaattgt gacaagatag
     2341 tgccaggtat gttaatggct gctgcaagac ttaatatacc aagtattgtt gtgagtggag
     2401 ggcctatgct tccaggtaaa aaaaatggga aagtatatga ttttaactct gcaatggagg
     2461 gtgttggagc atgtaaagat ggaacagtaa gtgaagaaga attagaagag ttagccatga
     2521 actcttgtcc tggatgtggt tcatgttctg gtcttttcac agcaaatagc atgaattgtt
     2581 taacagaagc tttaggcatg ggtataccat ataatggtac tgctgcgtca cattctggag
     2641 aaagaaaaag gatagcaaaa tatgcaggta tgtatgttat ggagttactt aagaacgaca
     2701 taaaacctag agatatttta acaatagatg cttttaaaaa tgctatagct gtggatatgg
     2761 caatggctgg ttctacaaat acagtacttc acttacctgc aatagcttat gaatcaggaa
     2821 tagagcttaa cttagatttt tttgatgaaa taagtgaaaa aactccttgt ttaacaaaat
     2881 taagtccaag tggaaaacat catattgaag atttacatat ggcaggagga ataccagcta
     2941 taatgaacga actttcaaag ataaatggaa taaatttaga ttgcaaaacc gtaacaggca
     3001 agactatagg ggaaaatata agaaattgtg aaatagaaaa tgaagaagta atacatacat
     3061 taaagaatcc atatagtaac caaggtgggc ttgcaatatt gaaaggaaat cttgctctaa
     3121 atggagctgt tgtaaaaaag tcagcagttg cagaagaaat gttagttcat gaaggaccag
     3181 caagagtttt taattcagaa gaagaagctg taaatgctat ttttggtaaa aaaataaaca
     3241 aaggtgatgt tatagttata agatatgaag gtccaaaggg tggtccagga atgaaagaaa
     3301 tgctatctcc tacatcagca gttgcaggaa tgggacttga taagcatgta gcacttctta
     3361 ctgatggtcg tttttcaggg gcaactagag gggcatccat aggccatatt tctccagaag
     3421 ctatggaagg tggtttaatc ggactagttg aagaaggaga tataatttct ataaacatac
     3481 cagacaaaaa attagagtta aaagtagatg aagttgaaat agaaaataga aaattaaaat
     3541 ttaaaccttt agaaccgaaa ataaagcatg gatacttaag tagatatgct aaactggtaa
     3601 catcagcaaa tacaggagca gttttaaaat agtagactat atttatgtaa attagaaaaa
     3661 gttaagaaaa tattaattgg atatcttagg tgttatagca ctaatgaggt atccttttta
     3721 ttttgtatga aaaacatagc aaaatcttga ttatctttga aaacaataca tctctattat
     3781 aaggaataca agtacagcat agagatgtat cttttagacc ttgttgaggt aatacaactt
     3841 tttaaaagtt tgatgtggaa tgcttttcgt tccatctgaa ctatgaagaa attgaaagtc
     3901 agttaattct tgacataata aatattaaaa tgtataataa aaaacaaaca gacagtctgt
     3961 ttttaggagg gaaatatgaa tagagaagaa aaaagtaaaa atagtaaaga aaaaattatc
     4021 caatcagcat tttcactatt ttcgtctaaa ggatatgatt caacatctac acaagatatt
     4081 atcaatttat ctggtctatc tagaggtgca atgtatcatc actttaaaac taaagaagat
     4141 atactgagaa gtgtcacaaa agaactttac tcacaaatga ataatttttt agagcatctt
     4201 gttgctgatg acacccttac agcaaatgaa aaaataatag aattggttgt tcatagtgcg
     4261 aatgattaca cacgtagaaa aatggtacat tgtagctggt tagaaaaaat cccattcgct
     4321 ttaatagagg aagttcgtaa tctcaacaat gtagttgcac ccaatattgc taagataatt
     4381 aaacaaggtg ttgaaaataa agaattttct tgtgaatatc cagaggaatt agctgaaatg
     4441 ctcgttttta gtattgatat tttacttgac cctgtattat ttaaacgtga atacagtgaa
     4501 gtatgtaata ggttggattt tttattattc atgttaaaaa aaatggatat tcctctaatt
     4561 gatgagtacg gtattcaaaa atttaaagat ttatttaaac aatgataata ggaaaagtga
     4621 ggaatagact atgttttata atgcaaaaag ctgtcaaatg atgataggaa gtaatacagt
     4681 gaattatatt gaatttggta gtggtaagaa gacactaatt attttaccag gattaggaga
     4741 tggtttattt cctttacatg gaaaaataca ggcgattgct tttgctttta gatataagca
     4801 atttacaaaa gattataagg tttatgtatt tagtagaaaa aatcaaatta cagaaaaata
     4861 ttccacaagg gatatggcta aagaccaagc agatataatg aaaaaacttg gaattatgaa
     4921 agcagaagta atgggtgttt ctcaaggtgg aatgatagct caatatctgg caattgatta
     4981 tcctgagtta gttgagaaac ttgtgttggc agttacttct tcaaagcaaa atgatactat
     5041 ccaaaatgtt atttgtagtt ggattgatat ggcgaagaag cagaattaca atgatttaat
     5101 gattgacaca gcaaagaaat cctattctga aagatattta aaaaaatacc aattatttat
     5161 tcctttttta ggaaaagtag gtaaaccaaa ggattttaaa cgatttatta ttcaagcgac
     5221 ctcttgcata gaacataatg ccttttccga attaaataaa ataacatgtc caaccttaat
     5281 tataggaggt gctaatgata aaattgttgg aaataatgct tcttttcatt tagcagaaaa
     5341 aattaaaaaa agcgaaatat ttatctatga gggattggga cacgctacat atgaagaagc
     5401 acaggatttt aatgaaagag ttttagagtt tttaaataag taaacacctt tgttaaaaat
     5461 atacatatga agattggaaa tttaatgtta aaaatagaaa catgaaaata tgcttaactg
     5521 gtatttttac tattcataac caatttttga tacattatct actataaata caaatatagc
     5581 ttcaatgtga ttatatattg gtgtattggt aaagcactta tacaaacaga ggaattttgt
     5641 aaattcatat tatacccaca tttgttaact tatgaaaata taatcaaaat ttttatgaga
     5701 tttttatata aaaaacgccc taaaaatctt attatcccca taaacactgt atctaaaagc
     5761 atattcaata ggaaataaat cgtgatatta ctacgaattt actactaatg aatgagcctt
     5821 gatacgtctt atttcccaga tatgcaaaga tatggcatgg cacatcagta aaaattgaat
     5881 acttatatag actatggaac gtacactttt ggcgtttctt ttctatttcc agatgttctt
     5941 ttcagaacgt ctttttttca tacccaaaat cgaaaggaga aagagaaaat atgaataagc
     6001 tagtaaagcg attgctgaca gggacgctcg ccattgcaac cattcttacc gcattgcctg
     6061 tgacggtggt tcatgcttct ggcaatcaat actggacaga atcagcagaa cgtgtcggct
     6121 acattgaaca tgttatgaat gatggttcta tcaaatccac attaaatgag ggacacatga
     6181 aagttgaggg cgaaactgcc tattgcgtgg acatcaatac aaatttcaaa aatggatata
     6241 aaacaaggta tgacgcaagc tcccatatga gtagcgatca gattgcggac attgctcttt
     6301 ccttagagta catcaagcaa tatactgctt ctcatacaaa cttgaattac aagcagggtt
     6361 acttattgga acagtgtgtt gtctggcaga gattgagtga acagctcggc tggcaatgtg
     6421 ataacgtcag agcttcctat aatgaaatct cacaggcggt acagaataaa gtttacgctg
     6481 gtgcgaaagt atttgtgaaa gcaaataagg gatgctatga atgtggcggt tacatctaca
     6541 ctggcgaagg acaggacatt ggacagttct gggcgaagtt gaatgtggga aatgaaaagg
     6601 tcaaaaagac ttcttccaat tccaccctct acagatggca acgtcaatta ttcctttgag
     6661 ggggcaacat ttggcgaatc ccatattgta gtcacagata aaaacggtca gttctctact
     6721 gcttcaagtt gggctttccg taaggtaaat acaaatgctg gaaaatccag tgaggatggt
     6781 gtatggtttg gtacttctga accagacgac agtaaaggtg cattacctat gtgattgagg
     6841 aattaaagtg tgattccaac gccggattta agctgattcc agcttttgag gtggtcgtat
     6901 ccagaaaaaa agtgaccgta gatttaggga cacttactga tgaatatgaa aaagaaatca
     6961 caatccatac cacagctacc gacaagaaaa caggcgaaaa aatgattgtt gccggaaaag
     7021 acatcaagat cgtggacaaa gtcacacttg atggcttaga aactggcagt cacagaaaat
     7081 tacaccgtga ccgttcatgt gtatacagat ggtgaaatgg gtcattaccc agaatcctac
     7141 ccttgctccg gtggtacaga aatcaaagta tgaaccgaaa gcacagggag cagatgtcag
     7201 cgtcagctcc gatacgttca aagacgctac tactttcttg gaaacattct ttaaactcta
     7261 tccgacagct acagaaaaag aacttgccta ttatgtcaaa gacggtgtgc ttgctcctgt
     7321 ttctggcgac tatgtatttt cggaactggt aaatcctgtc tttaccaaag atggcgataa
     7381 tctcaaggtc agtgtgtccg tgaaatatct ggataacaag tcgaaaatga cacaaatctc
     7441 acagtatgag cttgtgcttc acaaggacga taattggaaa attgtaggat aaatattaca
     7501 gcagaccagc tatgacaatt tcaaatacat atactaagtt ttaaaaatat acatgtaccc
     7561 tattgacttt ttgggaaggt acctgtatat tatttgttaa aggtacctgt tgaaaaggag
     7621 gtcatactat gaataatatt tattctgata tctatgagaa actatcaacc ttgcaatgga
     7681 ttatgaaacg ccatcagatg ttttgtcagg cagagtctgg tccatttgct gatacatcac
     7741 gaggacaagg aagaattctt gctatgttaa aaattcagcc agaaattgca acaaaagagt
     7801 tggcatattt attgggaata cgccaacaat ccctaaatga gttgcttaat aaaatggaga
     7861 aaaatggcta tgtagaacga aaaccatctg aaaatgataa acgcgttatg attgttcatt
     7921 tgacagaaaa gggaaagcaa gttcagcaac cgaaaacaga ctatcaaaat atctttaatt
     7981 gtctacttcc agaagaattg ctacaaatgt cgcaatattt agatcgtatt attgaagctt
     8041 ttcaattgca aaatggaaat gctttagaag aaaacaatat gattgactgg atggctcagg
     8101 caagagaacg tatgggcgat gagcattttg aacagttaat gtctatgcgt gaaagagctt
     8161 ttggacatat gagaccaccc aaagatatac cgggagctga acgcttttct gaaaactata
     8221 acggatatgt tccagataga gacggatttc agccaagaaa ctttaaacca gatatcaaat
     8281 aacaaaaggc actgtaaaat tacagcaata agccctatgg agattttttg aactccatag
     8341 ggcttatttt ttgaaaagga gacgaacaaa atgaaccaga aaaatgaaaa ttactggctt
     8401 ttagacgcac ctgtcacaaa agctatatgg catatggcga ttccaatgat gcttggaatg
     8461 tcaataaaca ttatttacaa tattacagat acattcttca taggcagatt aaatgacaca
     8521 gcggctcttg ccacaatctc actgctgtta cctttcacga ccattttaat ggcaattggg
     8581 aatttgtttg gaacaggtgg aagcactttg ttttcacgac tgttaggaag tgaaaatacg
     8641 gacaggacaa aacaatgttc agctacaaca ttatggctat ctttcctgtt tggactattg
     8701 actgcaataa tatccatcat tttcagtaac tatattatcc gacttctcgg tgctgatagt
     8761 aatacttttg cctatgtcaa acagtatctt attttttatg gaatgggtgc tccgtttatt
     8821 attgccaatt ttacgctaga acagttaatt agaggtgacg gtaaatctgt agaatctatg
     8881 attggaatga tgataagcat tggtgctaat atcattcttg acccaattct gatgtttgga
     8941 ttacagcttg gtattcgtgg ggcagccatt gctacagtaa tcggaaatgc tttcgctgtt
     9001 atctattata ttgtctgtat acaacgagca gacaatcagt tatctgctct tccaaaatat
     9061 ttcaggcttg aaaaacaaat gctaaaagaa atttttttag ttggattatc tgcaatgttg
     9121 ttagatattc ttttgattgt ttcaagcctt atgtttaatt actatgcact aaaatatgga
     9181 gattatgtgc ttgccggatt tgggatttct caaaaacttg tgcagattgt cgacctaatc
     9241 ggcatgggac tttacatggg agtaattcca cttattgcta ctgcctatgg tgcaagaaat
     9301 gaacttcgtg tgaaagaaat cattaaaaag actgctctct atttagcact agtaattaca
     9361 tgtttgttta ctattctatt tacatgcaga aactttattg ttcattgttt ttcaaatgat
     9421 tcagatgtaa ttcgtatagg tgcgtacatc ttaaccgttc aactctgttc ttctttcttt
     9481 gcggcaggag cgggtcttct aacgggaatt tttcaggcaa aaggagaagg aactccggct
     9541 gttgttatgt ccgttatgag aggtattatg ctcataccag caattatctt cggcaattat
     9601 ctctttaaaa tgaatggagt tattttttct ctgcttgtag ccgaagctat ttcatgcatt
     9661 acagggcttg tattatataa attgaaaaag taatgctgaa ctccatcaga cttgttaaca
     9721 aagttagtga tggttataaa aatcatcaac aataaattaa gagatttcta tagaatgagt
     9781 atagattggt aggagctgga aaaatatgat tgggcttaaa aaaagaaata taaaaaaatg
     9841 ttgaaaactg gtgatagagc tggagatgta tcattagctg atattcgggc taatatagaa
     9901 gccactattg atgaagacat gaacagtcca gccccagagg tacaggcaaa tttcaaaaag
     9961 tattttggca ataaacgtcc tacaccagaa gaatatattt acaagattac aaaaaaacaa
    10021 aagtttgatt tacgactatt tgttgcctgc ggagtatatc aacaaataag cgttaaagaa
    10081 tctgcacaga aaaacagaga aaataagaag cgaatcactt cttattctct ctgctgttca
    10141 agataccatc aatcgtacct tgaatgattt ttaattcgtc atcactcaat aaatcaagtg
    10201 acgaatctat ctgacggcta actgtgcttt tttccacatt cttcgctgga tagaaatact
    10261 cgtcaacaga tatattgaac atggtaacta aatcatggaa taaatgaaag ctagggtgtt
    10321 tcccgatatt ttcaatatct gcgatatgac gttctccgta aaagacttta tcgcctaaat
    10381 catttctgga aagccctgct ttctctctgg cttctctgat tgcaagtcct aaaggacgaa
    10441 aatcaaagct gtgcgtatct ttcttttttc tcatttttaa tcacctagca tgagtttata
    10501 ctattttcac aggtttgctc tgctcaagga gcaatttgtg attctaagta aaacaggcag
    10561 ccggcaccga caaccgaatt tattcctttt ttttagttta tcatcagccc ttgagcatga
    10621 attaaaaact catatatcag atgttttaaa tacagtctat ttgttattag tgcagatagg
    10681 ctgttttcat attttcaaaa agtttttcaa ttctgcaaca aatcacaccc tgctgtacag
    10741 atatggtgca gaaagaggga tacatacctt tcacttcata gagaaagggg gtatgatttt
    10801 gaaaccatca gacttccaaa agacgataca gtgtcagttg gactgtaagc tcaaaaaggt
    10861 tgtgaaaggc agtgtccgta actaccgcaa ggaattagcc agatgacagg caaaggaagt
    10921 acccttttgt gagcttccag aaattgttat tgagaaattg attgtctggg atgattacga
    10981 aagtgactat acgacattcg atgtgtgcag tacggaaatc cgtgtgcttg atgaagaact
    11041 tgaaaaatac aggatatatc ggcatttacc aacttatgaa aagataatca gaaatttagt
    11101 gtatttttat aataaaaata taatgtttgt atacaaaaat attaaagaca ttttagtaag
    11161 ttttgtatat aagcaaacat gtatttttta atatagttat ctaaatatta ttttatatac
    11221 aataaaatag gactc
//
LOCUS       DAEPUT010000116        10753 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.120, whole genome shotgun sequence.
ACCESSION   DAEPUT010000116 DAEPUT010000000
VERSION     DAEPUT010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.120"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            215..1375
                     /locus_tag="KRL22_003472"
     CDS             215..1375
                     /locus_tag="KRL22_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH1273907.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1718..1879
                     /locus_tag="KRL22_003473"
     CDS             1718..1879
                     /locus_tag="KRL22_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273908.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2072..2701
                     /locus_tag="KRL22_003474"
     CDS             2072..2701
                     /locus_tag="KRL22_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBH1273909.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2940..4199
                     /locus_tag="KRL22_003475"
     CDS             2940..4199
                     /locus_tag="KRL22_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH1273910.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSNGKVIKKEHISNSSYKELKK"
     gene            4457..5452
                     /locus_tag="KRL22_003476"
     CDS             4457..5452
                     /locus_tag="KRL22_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HBH1273911.1"
                     /translation="MYEEVTGLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5698..6765
                     /locus_tag="KRL22_003477"
     CDS             5698..6765
                     /locus_tag="KRL22_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBH1273912.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDVMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKGKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7299..9209
                     /locus_tag="KRL22_003478"
     CDS             7299..9209
                     /locus_tag="KRL22_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH1273913.1"
                     /translation="MNSNTFERLQLNEVKDLIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNVGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9272..9895)
                     /gene="ytaF"
                     /locus_tag="KRL22_003479"
     CDS             complement(9272..9895)
                     /gene="ytaF"
                     /locus_tag="KRL22_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HBH1273914.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            10083..10727
                     /locus_tag="KRL22_003480"
     CDS             10083..10727
                     /locus_tag="KRL22_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273915.1"
                     /translation="MEQNNKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
BASE COUNT         4396 a         1059 c         1766 g         3532 t
ORIGIN      
        1 taattgttga aaaagatttt aaattcagat tattcatttc taaagtaatt aatgtgcaaa
       61 tctttattaa tatatgtcaa tagttaggta tatatgtatt taattagcat gatatagata
      121 aaagtattta ttttaattgt ctattatctg aaaaagtctt tacttagaaa tcataaaaat
      181 caaattaatt aggaaaagaa agggtgtgta taatgtgatt gagactggat ttgtatattg
      241 tagtttcttg gttgtattcg taggtgtaat tttttttatg gttgataaat tgaaatggaa
      301 ggtatttgat gttattaatc caatgctttt aatatactta ggttcagcta tacttggatc
      361 atttggttta tttgcacaga atgaagatgt tggaacgtat caaaacataa taacagtgaa
      421 cttccttcca ttaatgttag tgtttttgtt aattcaatgt gatttaagaa aaatattaaa
      481 gatggggcct aaaatgttat tatcattttt ctgtgctaca tttacattta tgcttggatt
      541 tgttatagca ttcataattt ttaaaaattc aatgggtgca gattcatgga aaattcttgg
      601 ggcagcatct ggttcatgga taggtggctc atcaaatatg attgcagcag ctaatgctct
      661 aggagttgca gaagaaggac ttagttatgc aatacttatg ggttctatag gatatacagt
      721 atggatgtct gtttgtctaa tgtctgtgaa atttggacct aaatttaaca aatggacaaa
      781 gtgcgataca agttttatag atgaggttac atcaaaactt gaaaaagaaa ataaagataa
      841 tacggcacct acgtttgtag aacttatgat tttactttct gttgggtttg gagttgcgtc
      901 ttttgcacaa attgtatcca agatacttcc aacttcaggt atacttaatg aaactatgtg
      961 ggtagtactt gttgcatcta cagtatcaat attattgggt atgacaaaaa tatcaaagct
     1021 taaagggagt acactggtag gaaatgtgtt tatgtattta ctccttgcag ctacaggtag
     1081 taaagcaaat ttctttggat tgtcagaagc acctgtttac ataatgtttg gattggtagt
     1141 agtccttgta catgctattt catttatagg gcttgctaaa ctatttaaac ttgatttatt
     1201 tacttgtgaa gtaggaagta tagctaatat aggaggagta actacagctc caatgattgc
     1261 tggggttcac aatcctgtat taataccagt aggtgtactt atggggcttc taggaaatat
     1321 tatagggact tattgtgctc ttatggtaac tcaaatatta catatgttag cttaatgaaa
     1381 atatggtata aaattaataa tttaaataag aaaagtcatt tcaatttaag cagaagcttt
     1441 tactgaaatg gctttttttg tttgacaaga taatctattt caagaagatg ttttgacata
     1501 tttagtgtat aatattgtaa aatttactaa aaacgagata tatttaattt ttatattgaa
     1561 tcgaacgtct gtatgatgta taataaatat acagaacgaa tgtttgcaga acgggtgttt
     1621 tttgaattta ttttaataat ttatgaatat atatcagaat gcataaatat atttaaatat
     1681 aaagattaaa aagaatttaa aggagtgttg ataacttatg ataattccat caagaagaat
     1741 acaagatata acattaacaa atttaaaaaa tggtgaagta actttaattg aattggatga
     1801 aatatacaag aagatgggat ttttatttgt tgttagtgaa ggcaaattga aaaagataaa
     1861 aaaggagaat catcattaga aatgaatgaa ataataaata ttataatagt ttataaaacc
     1921 taacttatgt agaatataaa tacttaagtt aggttttttt gtgataaagt ttataagtac
     1981 tcaattttat aagataaata atggtcttaa gtgaaaagta aataagttta aattttagta
     2041 agtattatat tgcataagag gtgatattat tatgaaaata gtaacctaca atattcataa
     2101 aggtatggat tcaaataata gattaactct aactaaaatg gggttatatt taaaacaatt
     2161 ggattgtgat gtaatttgtt tgcaagaagt attatatcct caatttttag ctttaaaagc
     2221 tgttttaaat atggatggtg tctttgctac aaatgtaaaa aaagtaaata tgatatatgg
     2281 tatttgtaca tttacaacat ctaaaatgtt aaacagtaat cattttttct taactagcaa
     2341 aaaagaacaa cggggagctc tttgtataac tatagatgca tatggaagaa ttataaatgt
     2401 aataaatact cacttgggac ttgataggca ggagagagca aaacaattag acgaaataat
     2461 agactatagg aacagattag tggggatagt tattttatgt ggtgatttta atgagaaaaa
     2521 tgtcttttta agtatgttta atgatatggc tatttcacta aacaagtctt acttaccaac
     2581 atttgaaaaa tcaaactcta gaatagatta catttttgtt aataaaaata ctgaactaaa
     2641 aggatacaca gtagaaaaaa tttacctgtc agaccattat cctgtaatag gttacattta
     2701 aatttcaata taaatgaaat tagttgttat aaaataaaca attttttgtt aagaaatagt
     2761 aaaagaaata taataaaaaa tatcaaaaat aaaactaatt ataagacata aatttacaat
     2821 aaagttacat ttgattaaat tccttgttta acaaaagcta ttcaaatata atctaaggta
     2881 gttttgaaat gggaactcta ttatgcaaat ttaagctagt gttaaaatga ggtgaagtta
     2941 tgggcagaag aacaacaaga gtttcaagat taggtaaaga aaaaaaacga agtgttttaa
     3001 ttgtattggc agctttagtt ctaataatgg gtggatttac ttattttttt aacagtaaat
     3061 ttctgtacaa tgggaaaatc gctaaaaatg tatatataga aggagtaaat gtatctgata
     3121 tgactaaagc agaggcatta aaagctataa cagataagta tactccagaa gatttaaatc
     3181 ttgcttatga tgggaaaaaa tatacaatat caccaaaaga tattgattta aaatatgata
     3241 cagaagatgt tgtaaaagat gcttatgaaa gtacaaaaaa agggtcctat tttcaaaact
     3301 taaaaaaata tattgatata agagtgaata aggcaaatat gaagataaaa gctgaatatg
     3361 atgaggcaaa acttagttcc aaagtgtctt ctatagcaga tagtataaat gttaagatga
     3421 aaaatgcttc tattagtgtt ggaagtggtg gactaagtta tacagactct gttgtaggta
     3481 gagaatttga tttggcagca aataaagagt ctatatataa tatgataaaa aataaagagc
     3541 ataaaacttt agaacttaaa gtaaatcttc aaaaaccaga tataacaact gaacaagtaa
     3601 aaactgtaaa ttctgttata ggtcaatatt caactactta ttcacaagct gtagagggta
     3661 ggtcatataa tgtaggatta tcagcaagaa aaactagtga tgtattatta atgccaggtg
     3721 aagaattttc atacaataaa cttacaggac ctagtaataa agcaaatggt tacaaagatg
     3781 cacctgttat agtttatggt aagctagaac aatcagcagg aggaggtgtt tgtcaaacat
     3841 cttcaacagt ttataatgcg gctcttcttt cgggtatgga gataactcaa gttacaaatc
     3901 attcatctgc atctacttat gtgcctaaag ggagagatgc tactgtgagc gatggaggat
     3961 taaacttaaa gtttaaaaat ccatataagc atcctgtata tattaaaaat tatgcaggtg
     4021 gaggaagtgt atcatcagta atctatggta attctggtga caaaccaaat atatctatag
     4081 aggtaaaaca aactggtcag aataaatatt ctacatatcg aatatttaaa gattcaaatg
     4141 gaaaggtcat aaaaaaagaa catatatcaa atagttctta taaagaatta aaaaaataga
     4201 taatttttta gagaaatatt tgtaatataa aagggagtgt ctcaaaatga actttttagt
     4261 ttagagacac tctttttatg tgaaatcaaa tatattttca tcatttcaac aatacaaaag
     4321 aagcatatct ctattttgag acagcctttt ttgtaaaaat taacactatt agttcttgtt
     4381 ttaatattac aatcattaat atatagaaaa tattcctata tattggtata attgtaaata
     4441 gatttagtta tataaaatgt atgaggaggt gacagggttg aattttatag gcaatagata
     4501 tgaggtagta aattctgacg acgttttaga aattaacaaa atctataaag ctagagatgt
     4561 tttttacagg aaaaatgtgt taataaaagt tataaagcac aataattata tctgtgaaga
     4621 ttttgtttca aatttaattg atgaaagtac tgctttagat gagataaact ctccttatat
     4681 actaaaaata atagatgttg ggattcactg tacagaagaa acaacattat attatgttgt
     4741 aagtgaagac tttaatggta tcggactaga tgaattaatt ctaggtaatt atcttcattt
     4801 agaagcaatt gtaaacataa tgatacaagt tttaaaagct ttagaaatga tacataggaa
     4861 tcattcatat catggtagtt taaaatcgag tagtataata gtagatacag aatacaatat
     4921 aaaaatttgt gattttggaa ttacaaaagc aaataatggg gttaatacaa gaagctatgg
     4981 aaacaggaga tatttatgcc cacatcaact atgtataaat tatactgata aagaaagtga
     5041 tttttttgca acaggtctta ttctatttga atctatattt aaaaaattgc cttttggaga
     5101 atcaaattca gaagaaaaaa tgctacaatc tattgataag ggattagatt ggaatagtat
     5161 aaaagcaatt aatggaaata ctgaacttat aaatgttata aaaaggcttc ttggaagaaa
     5221 taataagtat accagagcca atgatattat tattgattta agtaaagtaa tgtatgaaaa
     5281 agcatatata gaagttgaag atgagaaaga agaagagcag aaacaagaca aagttataca
     5341 agttaaaaaa gaatataaaa gtaaaatgag aaaaaaatta cataaaaaac ttgttgttgc
     5401 cggtctagct atagtcatga tttcaatgat tattattagt tccataatat aaaaattgta
     5461 tattaagtat tttaaaatca atgtctataa aggatataca tagaaatttt agtgtagtct
     5521 taaattatga aaggaagtgg ttattatgtt aacaaaaaat aatgaggtat taaacgtcta
     5581 ggagtatttt aacaaatagc cacctgcttt tacagtttag aataaaaaag ctgtggctaa
     5641 aggtcacagc tttttgctac tttttaaagg caggagaata ttaaaaagga gcaaattatg
     5701 agcaatataa aaataatagc aagtaataaa tgttggattg aagatatagc aaggaaacaa
     5761 cttgaagata tttcaaagtt aaatggaatt ttaagagtag taggattacc tgacttacat
     5821 gcaggtaaaa tacctgtagg tttagcagtt gagactaaaa atattattta tccacatata
     5881 attggaaatg atataggatg cggaatgact ttatttaaaa ctggggttct aaaaaagaaa
     5941 tttaaaaaag acaaatggat taaatcactt agtaagatta aagatttgtc tgatatagaa
     6001 ataaaaaaca catataaaga agaatgtcca attttaaatt taggaactat agggagtgga
     6061 aatcattttg tagaaattca atgtataagt gaaatttata ataaagaaca atttgaacaa
     6121 ttaaaatttt catctgatga tgttatgatg ttagttcact gtgggtcaag aaattatgga
     6181 gaagatattt taaaaaaatt ttatgataaa gatggacttg aagttgaaag tgagaaagct
     6241 atagattata ttaaaaaaca tgataatgct ttaatgtggg cagagcgtaa tcgtgaagct
     6301 atcagtaaaa aaattatgca gtcaataggt acatctggag atgttgaaac aatattctct
     6361 ataaatcata attttataga gaaaagggaa gataaattta tacatagaaa aggtgctgtt
     6421 tcaagtgaaa gaggagctgt gattatacca ggttcaagag gcagtctatc atatatagtt
     6481 atgcctactg aaaatacaga gatatcttta tattctctat cacatggagc aggtaggaaa
     6541 tggtctcgtt cagtttgtaa atctcgcctt aaaggtaagt atagtaaaga tactataaaa
     6601 caaactaaat ttaaaagtca gattatatgt aatgatgtaa atttattatt tcaagaagct
     6661 ccagaggcat ataagaatat agagcagatt attgaaagtt tgatagaata tgaacttatt
     6721 caagtagtgg caactatgaa gccattgatt acttataaag gataattttt aaagttaaaa
     6781 aagattaaaa ttatattata aatagctaat tttatagaac atttaaaagt gttttattat
     6841 tagctatttt tttattttgt agagacgata atttatagag ctaaattctt tgatatataa
     6901 tgattacaaa gttagactgt attggaaaat gcacatacat gaattgatga caatataagt
     6961 gattcccaaa tataaatgaa agtataagct tattttcact ataaaaattt tcactgtaca
     7021 aaaacattaa tgacattatt tttattgaca taaatatata atttatggaa taatattaga
     7081 agcactgata taagtgttta aataagaata gaaaaggaga agtgttttat gaaaaaaaat
     7141 actaacatta atgagtccgg agttaaactt cttaataaat aaggagtttg atatataata
     7201 actccttatt tattaagttg ttcgcaaaat aactattatc aaagtaaatg atagggtgat
     7261 ttaaaagacg atgacttata aataaaggag aaaaaataat gaatagtaat acatttgaaa
     7321 gattacaact aaatgaagtt aaagacttaa taaaaataca ttgtgtaagt tcgctaggaa
     7381 aaaatttaat agataaatta actcctagtg ggaatattgg agtagtaaga aggaaattag
     7441 cagaaaataa agaagctaga aagataattg aaaatagtaa tcacatacca cttgaaggat
     7501 tgtttaatgt aggttctaca atagataaaa ttgaaaaagg aatgataata gaacctgttg
     7561 aacttgtaaa tattgaagat tttttaagag gttgtaggaa gatgaaagct tttatgttag
     7621 aaaaagaatt ttattcacct acattaagtt cttatgcctt aaatataaca gaatgtaaaa
     7681 gtatagaaga tgagataaat tactgtataa aatctaataa agttgattct aatgctagta
     7741 aagaattaaa aaagataaga cgaaatatag aaattacaga aggaaagata aaagatagat
     7801 taaataaatt tataacatca actgtaaata aaaagtatat acaagagttt ataataagta
     7861 aaagaaatga tagatatgta ataccaatta aatcttctta taaaaatgaa gttaatggta
     7921 ctatattaga tacatcatca aaaggaaata cggtatttat tgaacctatt agtgtttcaa
     7981 atttaagtac agagttaact atgttaaaag ctgatgaaac tattgaagaa tacaaaatat
     8041 tatcttattt aacagaactt atatttgaga agataagtca gataaaatta aatatagaga
     8101 tactttcaga atacgatatg gtatttgcaa aagctaagta tagtcaaaaa ataaaaggaa
     8161 ttactccaaa aataaataat aatggctata taaaaataat taaaggtaaa catccacttc
     8221 taacaggaga tgcagtacct ttagattttg aaataggcaa aaattataga agtcttataa
     8281 taacaggtcc taatgcagga ggaaaaactg taacccttaa gactgttggt ttactaactt
     8341 taatggttca atgtggattt gatatttctg caaaagaagg tagtgaattt agtgtatttg
     8401 aaaaagtttt tgtagatata ggggataatc aaagtattga aaatgcctta agtacttttt
     8461 catcacatat aaaaaatatt gcagagatta tgagtttatc aaataattct actcttgttc
     8521 tgtttgatga aataggaagt ggaactgaac ctaatgaagg agctggttta gcaatatcat
     8581 tattagaaga gttttacaaa atgggctgta taactatagc atcaactcat tatggagaga
     8641 taaaaaagtt tgctacattg catccagaat ttgaaaatgc tggtatgatg tttgataaag
     8701 aaacgttaga accattgtat aagttaacta ttggaaaatc tgaagatagt aatgctcttt
     8761 ttatttctaa aaaaatggga ataaaaaata gagttttaga tagagctaaa gaatatgtaa
     8821 ttgatagaaa ctacaattta gatttagtta aaagaagtaa gctacaatct aatattgaag
     8881 ataaaaatag ttctgaagtc attttaaact atacagatta taatgtaggg gataaggtaa
     8941 aattactaga tgaagatgat tttggaattg tatataagcc tatggacaag tttaataatg
     9001 tagaagtatt gtttaatgat aattttattt cagtaaatat aaaaagatta caacttagca
     9061 taaaagcatc agaattgtat ccagaagggt atgatttaga tgtattattt actagtttta
     9121 aagaaagaaa attagaaaaa gatattcaaa gaggttcaaa aaaagctctt aaaaagattc
     9181 agaaagaaat tagagagaat agaaaataaa tataaaaagc acaaaagaaa gcaatctaaa
     9241 gagaaaagtt tatctttaga ttgctttctt attaacatat cttcataaat ccaatgacta
     9301 acaagattaa accacttaac caagataagt ttaaatttac gtttttaaca aacatatttc
     9361 ctagtaaaca accaagtaat actgcaatta tatttgatat taaagaaaat agaataactt
     9421 gtatataatt cacacctaca aggccactac caaaaccgat agctaatcca tctaaactta
     9481 aagcaagtgc aagtgtaaat gcttcagcag atttaagcac tttagattta cttgtatcta
     9541 agacatcagg ttcgatactt acattaaaat ttaatttaag gtctaacata ttaaaattat
     9601 aattctttga gtgtatagat tttttcttaa aataagattt aaaaaaactt tcaattagtc
     9661 tagcacttcc taataaaaat aaaataaaga aacatattaa cattgttata ttttgaggta
     9721 aaaagtctct aactattgta cctgcaaaaa gcgatattgc taaaatagct gaacaaacta
     9781 cgctgataat tatatttgaa tataagggaa ctttaacttt atttacgcca tatccaaagc
     9841 ttgtcacaaa ggcatctata caaagagaag taactaataa aattgattca atcacagtag
     9901 attaacatcc tttctcttaa attttgtact tatattagtt atagtattgt aaaaatggat
     9961 aaattgttac agataatcca ataaattgtt gataaaattc caacatcata caacacctaa
    10021 ataacaaaag aatcatatca tataataata taaaaccaat cataataaag cgggtgaaaa
    10081 taatggaaca aaataataag gttgggaatt tcggtgattt gttgaagatt ttattagatg
    10141 aaaaagaatt atcaatggga gaactaagta aaaaaagtgg aattgataaa tctactatat
    10201 ctcgtatagc taataataaa caaaagccaa atataaatca tttagaaaag atggcaatac
    10261 atttaaatat taacctagaa gaactgttga aagcttcagg atatgaattt agaaacagca
    10321 ataatcaaat atttaatgca gatagtgatt ttagtaactt tgatgatatt cttggatttg
    10381 caaatttaat caatgataag aactttaatg gaaatattga aaaagagttg agtaagtgta
    10441 agttatatgt ccaaacagat gaaggtaaaa aattactttt tgataatttt aataaaaaaa
    10501 tagattctat tgaaaaacaa ggtcaattta cagatagatt aagacaaatg tatgctgatt
    10561 tttgtacaga tggacttaca ataaagaaat atttattgat tggaagtatg ctactttact
    10621 ttgttatatc aacagatgtg attccagact tcgtgttccc aataggattt atggatgatt
    10681 tagtagcatt aaatatagtt acaaaattac ttaaaaatga taagtaagtt ttagaatcat
    10741 atttaatata taa
//
LOCUS       DAEPUT010000117        10620 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.121, whole genome shotgun sequence.
ACCESSION   DAEPUT010000117 DAEPUT010000000
VERSION     DAEPUT010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10620
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.121"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            780..1532
                     /locus_tag="KRL22_003481"
     CDS             780..1532
                     /locus_tag="KRL22_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1273916.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            1522..3633
                     /locus_tag="KRL22_003482"
     CDS             1522..3633
                     /locus_tag="KRL22_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273917.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKRKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYRLPSVWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVINKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNEEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            4017..4727
                     /locus_tag="KRL22_003483"
     CDS             4017..4727
                     /locus_tag="KRL22_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1273918.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFIAVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
     gene            5169..6506
                     /locus_tag="KRL22_003484"
     CDS             5169..6506
                     /locus_tag="KRL22_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1273919.1"
                     /translation="MGTYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTESEFSLFLYIRLF"
     gene            complement(6842..7411)
                     /locus_tag="KRL22_003485"
     CDS             complement(6842..7411)
                     /locus_tag="KRL22_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBH1273920.1"
                     /translation="MKKRLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            complement(7763..8776)
                     /locus_tag="KRL22_003486"
     CDS             complement(7763..8776)
                     /locus_tag="KRL22_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH1273921.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKIFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPTYQVNVY
                     IDN"
     gene            complement(9388..10290)
                     /locus_tag="KRL22_003487"
     CDS             complement(9388..10290)
                     /locus_tag="KRL22_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH1273922.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGIVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
     gene            complement(10417..10536)
                     /locus_tag="KRL22_003488"
                     /pseudo
     CDS             complement(10417..10536)
                     /locus_tag="KRL22_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3952 a         1584 c         1212 g         3872 t
ORIGIN      
        1 catttctatt atattacaat ctcttattta ttacagttct ttattatact acagactttt
       61 attattacag catttctatt acattgcaaa gtcttattta ttacagttct ttattatact
      121 acagaccttt attattacaa cattttatta ttttaacttc tttactataa tatagtaata
      181 ttttaatatc tcaaaatcat atcaatcact tttcagcata gtctaaaata cttccacttt
      241 ctaaaattat ctatcatacc tatactaaca atacttttta acctttttat tatacatttc
      301 aattgttttt aacaacctat ttatttccaa aactccaata tattttctca attacattgt
      361 gttaataacc cctaaatcct ttcaaattat ttacaataca ttccattaaa taatcttact
      421 gctctataat tctttttttc tttttaaccc tactatacat tatttacatc atttttttca
      481 atacaacatt cgttattcta taaccttttt acttttacta tatacctttt ttctaactac
      541 accttcaatg ttccacatca tattacttta gcacaacaat taatacctaa aaataaccct
      601 ctaaatcctc caataatata atcaatttaa ctataataat aacctctcac actatccaaa
      661 caatatattt tcaaacatta caaaaaaaca tccaactatt acaatatatc tcatatccct
      721 cctccccttt caaatgctat cattgactta caagataaat gaaagtgagg atgatatata
      781 tgcttaaagt aaaccaatta tgtaaatcat ataaaacagg tagtaaaaca tatcctgtat
      841 taaaaaatat ttcttttgaa atcaacaaag gagaatttgt cgcaatcatg ggttcatcag
      901 gaagtggaaa aactactctt ttaaattgta tttcatgttt tatcccaatt gataatgggg
      961 aaataattct tggaaataat aatataagaa atttaaaaga aaaggaactt tcagaagtta
     1021 gaaaccaaca actaggattt gtattccaag atttcatgct atttgatggt cttagtgtat
     1081 ttgaaaatat atgtgttcca caaattatca aaggtagtca agtcttacaa atggaaaacc
     1141 gtgcaattaa tctatgtgag ctatttggta ttgaacatat cagaaaaaaa taccctgccg
     1201 aaatatctgg tggagaaaaa cagcgtacag cagtagcaag agcactcatg aacaacccag
     1261 atttaatatt agcagatgaa ccaactggta accttgatag taagtcttgt cgtacagtca
     1321 ttgaatcatt tttaaaagca aagcaagaat tagatgctac tatactcatg gttacacacg
     1381 atagctttgc agcaagcttc tgtgaccgag ttattgtgct taaagatgga ataatttata
     1441 aagaagttgt aaaatcaaat tcaagacata aattcctaga tgaattacta gaagttttaa
     1501 aagaaatggg aggcgctcaa gatgacaatt aataaattat acagtaaact tcgagcctat
     1561 aattggaaga actatactac tttattcttt tgtataatac tttctgtggt attagtaact
     1621 tcatatgctc taatttattt tagcccaaca atacaaaaca tacttccaac tggtggagat
     1681 agcagaaaac aggctacaat gatattctca gttgctatat taggatgcgc tgtctttact
     1741 acatacgctt cttccctctt tttaaaattt aaaagcaagg aaattggtat tttcatggct
     1801 ctaggaacag ataagaggaa attaaaaaaa cttctatttt cagagatatt gttaatttca
     1861 atagtatgct gttttttagg tcttatatta agtattcctg tatcttttgg tatatggaaa
     1921 atatttcaat tagtgattat tgataccaga gaaatgacat atcattttgg aactcaagga
     1981 ttcatatatg gatttatatt tagtgtattt gtgacattat gcatatttat actttctgta
     2041 aaatttatta atcgtacaaa tataattgat atattaaatg accagagaat atctgaacca
     2101 atacaggatg taaaggactg gtatggtata ttaggtataa tttttattat actaggtatt
     2161 tttctaggat atctcgtacc ttcactaact ataaacaaat taaattatag actaccatct
     2221 gtatggagct ttacttatct actctctctt attggaatat atatgattat gacatacata
     2281 gttgtacatg ctaaaagagg aaaacatcca gagaaatact ataaaaacat catatcaact
     2341 agcatgatga gatttatggg aagacaaaca gtaaaaaaca tgtgtgttat ttcatttttg
     2401 attgcaggag cattatttgc tgtattctat gttcctaata tggttacagg tatctatgat
     2461 actcttaaaa ataaccctat agattatact tttacctaca atcaaagaga taaacaggta
     2521 tcaaaaaaag atattgaaca attagcagat aaacacaata taaaaattca aaactatatg
     2581 gaaattcctt ctatagaatt aattgttgat ggtgtagaat caatatatca taaagatgga
     2641 actatcgaaa aggtatatat gaaaaaaagc tcctatgata tgttctttaa ttccaaagat
     2701 ttttccaagc taattggcaa accaataact ataaaaaatg gtgaatatct tgctgttata
     2761 aataaaggaa atgaaaatca agattataaa tataccaaat ttatatcaag cccagtcaca
     2821 gaaaaagaaa tcccctttag atatgctgga aaaataatat ttaatggttc tttttttcaa
     2881 aatagaagta tgaacgccta tgtccttaat gaggaggatt ataaatcatt tactaaagat
     2941 ttatccataa aaaattacaa taattctata ctatttaatg tagataaaga tacctatgct
     3001 tttgccaatg acttgaagaa agaaattata aaaagaacat ctaaggaaat gggcatgttc
     3061 agtggttatg atgaatacgt aaaaaaacgt tatgaatcaa ctggaagaaa atattttatg
     3121 gatgaagaat atccaagtgg tgaaggtcat ttaaaactag acccaaacaa caatcagctg
     3181 tatcttaatt ggaaatacta tcctaacttt aaaattttac aaagccaaga tatgataaaa
     3241 aacatggcag tcttcttaat gttattcata tatgtggcaa tcatatgttt tacagcagta
     3301 ggaatcattg catatacaag gggtgttact atagctataa atcacaagca ggtctttatg
     3361 gatttaaatc gattaggagc aaacaatgat tatataaagt tctgtattag aaatcaatta
     3421 aagaaagtat tttcataccc tcttattgca ggaagttttt taatttatct gtttaatttt
     3481 atgattatgt taaataatga tggtagaatc gtcaatagtg aggtcaatgc tcttttgata
     3541 aacttaggtt ttatagggat ttgtggggtt tatatgtacc ttatatatct attaacttat
     3601 aagaaattca aaaaaattat tggtatttta taataaggaa ggttgttaga tttttaaagt
     3661 aataaaatca ttggtgtttt ataataaaaa aggttattag atttttaaag taataaaatc
     3721 attggtgttt tataataaga aaggttatta gatttttaaa gtaataaaac cattactttt
     3781 tataataata aaagcatttg tattttataa taagaaagat tgttagattt tttaataaga
     3841 aaatcattag cacttcagaa taagtttaat agaatagttt taagtgtaag tatactaata
     3901 taaaaaattt tattttgcta tctggatata attgttattt cattttatat atctaggtag
     3961 caaaatatat tatatactta actatataaa tataaaactt gaaaggagat aaaaaattga
     4021 cttcgatttg tatttgtgat gatgaaaaac aacaaagaaa catgctgaat aaaatcatta
     4081 caagagaaat ggatttgtgg ggctacccct accaaataaa agaatattca aatggagaaa
     4141 gtctagtata caatctagaa cacgaaaatt attacataga tattattttt ttagatattg
     4201 aacttggaaa aagtaatggc gttgacatag caaaaactat acgaaaacat tcaaaagata
     4261 ctataatcat ctttgtcaca ggtttttctg actatgtatt tcatggatat gatgtaggag
     4321 ctttgaacta catcttaaaa ccttataaaa ctgaaaaaat atgtaaagta ttaaaagaag
     4381 cactaaaaaa attagaacaa tggaaagaaa actttattgc agttcagatt ggaactaatc
     4441 tttgtaaaat taatacaaaa gatatcctct actttaaaag cgagctaaga aaattaactg
     4501 tagttacctt tgataaaaca ttagaatact acggaaaatt aaatgatatg gaaactgttc
     4561 ttccctctaa ttttatacgt acgcatcaaa ggtatattgt caatctaaac catgtagata
     4621 gtataactca aacttatgcc aaagttcaga atgaaaaaat tcctataagc cgtaaaaaat
     4681 atcaagaggt tgtaggaaaa tttacaaggt atatgttaga atcttaattt ttgaagtcaa
     4741 tctctagaat tttatttttg aaacttaatt ttttaaagct tagtttttag agttttgttt
     4801 tttcaaattt aattttttga agattaattt ctagaatttc aatctttcaa aatttaattt
     4861 tttgaagctt agtttttaga gttttgtttt ttcaaactta attttttaaa gcttagtttc
     4921 tagaatttca atctttcaaa attcaatttt ttgaagctta gtttttagag tttttttcaa
     4981 atttaatttt ttgaaactta atttttaaaa tttcaatctt ttaaaactca attttttgaa
     5041 gcttaatttc tagaatttta tttttcaaaa tcaattcttt gaaatctaat ttccagaatt
     5101 ttaattttta agatttaatt ttttaaaact tagtttccag aatcttaatt aatagaaagg
     5161 tatattaaat gggcacttat tctttaatct ctacaagcat aaattttatt ctaatattaa
     5221 tcaatatttt catagccttt tttctttata agttgacttc ctattttata gactttagga
     5281 atcattggat tttcaaaatc atattgattt tgggctactc tattattagt caaatgataa
     5341 tatggctttc cgaccccgta aatattttgt ttacactatt cggatatttt atactactta
     5401 taatatgtag caaaagcaaa ttaattccta taatatcagt tgtcatgata ctttatccta
     5461 ttataattgg gcttaatttt ctttttataa acaaccctat atatgaggaa cttatacact
     5521 caaaagagta tattttaata ctttcaatag tccagataat ttctgctcta attaaattat
     5581 tattttggtt tttaatacat attttcctaa agaatagatt ggtcaatata aaacaatact
     5641 tatcaaataa aatatggatt tttattgata tggtgtgtat atcttcattt ttatcaatat
     5701 taattgctat tattctgcca cctactaatt taatccctat gggtagtaat aagaatatta
     5761 tcttaggcaa cttaccttat ggcacttatc taatcatctt gtcagcaatt ctggcaaata
     5821 tcggtgtgat acttctttta cagccattga ttgaaaatgt aaagatgaag atagaaaaac
     5881 aagcaaatca cctaaaagaa aaatactata acttactaga aaatcaacaa attcaaatac
     5941 gcaaaatgcg acatgatatg aataatcact ttcaaatgat tgaatcgtat ttagaaattg
     6001 aagatattgc tggagctaaa aagtatttta atcagttaaa aataggtata ggtactctta
     6061 gtggcaaaca attttgcaaa aaccaagctc ttaactcaat tttaaatctt cgtcatacaa
     6121 gtttggaaga aaatggtgtt gatgtgcact ttaatataga tatagacaat cacttgggta
     6181 tagaacctat agatttatgt actatttttt caaattcttt agataacgct atagaagcat
     6241 ctttgaaaat tcctgatttg tcaaatagaa aagtggtatt aaaggcacgt tgtgagaagg
     6301 agtattttag ctatttattg acaaacaaca aagtaaatcc tatcaataga aaacaagaac
     6361 tatttatttc agataaaaaa gatagtaatt ctcacggata tggtattgag aatattagag
     6421 aaattgttaa taagtacaat ggaaaattgg atatttctta tactgagagt gaattttctt
     6481 tatttcttta tattagatta ttttagtcta aaattagatt atcttatata atacaaatta
     6541 gattgtttga tactatgtaa aattataata acttataatt aaatatttac acatatattc
     6601 attaacttaa aatttaatca aatgtgatat tttatttacc ttagtaaaaa tgtgtgtgtc
     6661 tcaaaataaa ctttttagtt gatgaggcac tcttttttac atgaaatcaa atatattttt
     6721 atcctttcaa caatgaaaaa gggatttatc tctccatttt gaaacaagcc ctttttctat
     6781 taattacttt attaaaaaat ataatacgat atataagata aatatctaat tgtacctatt
     6841 tctaattata tctattagaa tacaacacct ttgccttttc agtaaactcc ctaacaaaat
     6901 ctagtttact atctgtataa gcatcacgat tatgctcata cttcttccaa aggtccaact
     6961 taagtttttc atactccttt gcaacatctg ggtggtcaat taagtaatct ctaaaaaaca
     7021 actcatcatt atcacctaca taccttatat gcaaatgaaa aactcgttct tcaaacccat
     7081 ctactgtata ccctttatta agtgaaagcc tactactgct ctcagacata caaatatatc
     7141 cattcgactc aatcaaatct ttaatatctt tcatattata atcaggaatt atctcaatca
     7201 gtatgtcaac aatgggcttg gcataaatcg tactcacaga agtacttcca atatgactta
     7261 ttctaacaat tttttgcatt ggcaatattc cagttagtct atattgttct tctttaaacc
     7321 aatttttcca acattctttg tgagtagtca aaaatatagg aaacaagttc cataactcct
     7381 ctaaagtcat atcttccaac ctctttttca ttagttacct ccttttaaat ttgtacttta
     7441 tattttttct ttttcaaatt tacttagtta atatttaact ttatttttta tcaaatcatt
     7501 tttctaatta tgtaaatttt tctaaattta gtttttaatg tattataaca gatttttacc
     7561 cttcttacac ttttgcattt ctttaaatat tagaacattt ttaatctaca attgtagtaa
     7621 ttttttcttt acctgtattt actggcattg gagcttctaa agaataattc attggcttta
     7681 atataattaa agtaaattta acatatgtga aagatactta ttaaaattat ttatattaat
     7741 ctcttgttaa actttgtatt ttttaattat ctatataaac attaacctga tatgtaggtt
     7801 ttgaattagt tctgttttca ataggtgttt gttttgaaag tggataaaat attgatttag
     7861 tagtaattaa atcaatttta aaatatgtaa tagaagataa taaacataaa ataactgcta
     7921 tcaaaatacc atttctgtac ttttcattaa acatactaaa cactcttttt ttaatatctg
     7981 actccttatg taatccagcc acaaatttat ttgaactatt tgaacctttt ctcattgcac
     8041 taattattgt caatgcataa tcctgcttct cttctatcgt acaattcttc aaaactcttt
     8101 catcacaata aaattcacaa tccaaatcta taaacttctc cattatatac acaaaaggat
     8161 taaaccaata aacacatttt aaaaatatca ccaaatactt aatataaagg tctttactct
     8221 taaaatgcat caactcatgc ctaaatatcc agtttaactc ttttaatgta taatcacatg
     8281 gtggtaaaat gacacacgaa ttaaaaaata ctggactttc aacttcatat gaatatttaa
     8341 gccgtatttt tttatttatc ttaagctctt ttaataaatt ttcataaaga ttttttatct
     8401 tatcatcctc aacatcataa gacaaatcat ttatcatatt tttaagctta atatatttca
     8461 ataaagtata aactaaataa aatatcgtaa tagcaatcca aacagagact aaaacagtac
     8521 tatatacaat agaaatacta ttaaaattgc ctaaacttat cttattaata ttaccattat
     8581 attttgactc attaaatata aaagtataat tcataaatgg taatgatagc ttaataatca
     8641 caataagcca tatatagtaa ttaaattttt tactgaaaat cttaaataaa gttattctaa
     8701 agactaataa aataactata aaaatacaac ttactaaaat tgttctaaag atatcattta
     8761 aaaatgaact aaccacagat actcaccttt cttatacttt tatatttata taatcatcta
     8821 cacgaatact aaactgatat gtaggttttt aattaacttt gttttcaata ggcgattgtc
     8881 ttgaaagtgt tttaaaagtt gatataacaa tgatttagga gtaataaggt caattttaaa
     8941 atatgtaata aaatataata agcatgaaac aactactatc aagataccat ttccaaactc
     9001 tataagcaaa aggggctaat acaaccttaa ccccttttaa ttattttcat ttataaataa
     9061 attctattct tcccaaaata tcgtaattaa aatattaatt aaaatatccc aatgagaata
     9121 tctgaaaaat cttctaccta ttttttcaaa ccctttattc ccattcctca tacaatagtg
     9181 caacttttag cacagtataa atataccatt agtccatata atctcattaa caaatatata
     9241 caattatttt cttcaaactc ttttatatct aagatatcac attttcattt tcttatatta
     9301 attccttaac tctctttcaa attaccaatt tttaattatc aaatcttcat taaatattct
     9361 atcattatta aacattcatc attatcccta aaaaatatgt gccgtatgtt ctttacacaa
     9421 attttccatc ttatcataca cagcaccact atctctctca tctgtcatag tcacaattac
     9481 atcacttggt ctaagaattg tcttacctct aggaataatt tcttctccac ctctttgaat
     9541 tgctaccaaa agacaatttt caggccactg tacatcctga attgccttgt tcgcaacagg
     9601 agagccaaac ataacagaga actggtctag tatcttttcg cccctctctt tatgtacagg
     9661 ttctccattt ttttcaagta acctctcaag aagactttca taaataggtt tagacttcat
     9721 aagtgtagcc acaatatatg ccacaattga aattactgat agtgaaagca tttgactaac
     9781 agaacctgtc atttcaaaaa ttaatatgat accagtcaaa ggggcacgca caatagctgt
     9841 aaaatatcct gccatagcca aaagcacaaa gttatttaca taatcgggat tcattccaaa
     9901 aactttaaca cctaccatac caaatattcc acctataaat gctcctaaaa caagcaatgg
     9961 aaaaaatatt ccccctggtg cacctgaccc aaaactaaca gccgaaaata taaaacgtat
    10021 aacaaaaatc aaaacaacca ttccaaaaat atattcatga cttgtaagtt cttcaactaa
    10081 attgtgtcca ctccccagaa catcaggcat aacaatccca agaataccag ccattataaa
    10141 tggaatcaac agttttccaa aggtaccaat tttaggaatc ttcttgtata aagactgcac
    10201 atatagagta aaccagttgt aaaatgcccc cataactcca agaataacac ctaaaatcac
    10261 tattaatcca taataatctt gtggcaacac atttccaatc tgaacctccc atgactaaag
    10321 tcacagggtt cctgcttcat agaattttgc atactaaaat atgtcttact aattctccac
    10381 aggctatccc cgtagttcct acggttctta cataagttat ttattttgaa ttgttattag
    10441 tcttaatcct tcttttaata tatttatact tgcatttata tctctatcgt gagtttcatt
    10501 acaactagga caaatccatt ctcttataat aatgttaaca aatgtaatta tttaaaacaa
    10561 ttatttagaa ggttttatat ttaattttaa ataacatatt taagaaccgt aagtcttaac
//
LOCUS       DAEPUT010000118        10211 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.122, whole genome shotgun sequence.
ACCESSION   DAEPUT010000118 DAEPUT010000000
VERSION     DAEPUT010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10211
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.122"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            30..899
                     /locus_tag="KRL22_003489"
     CDS             30..899
                     /locus_tag="KRL22_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1273923.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(1269..1901)
                     /locus_tag="KRL22_003490"
     CDS             complement(1269..1901)
                     /locus_tag="KRL22_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH1273924.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(1973..2326)
                     /locus_tag="KRL22_003491"
     CDS             complement(1973..2326)
                     /locus_tag="KRL22_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH1273925.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNVLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(2404..2607)
                     /locus_tag="KRL22_003492"
     CDS             complement(2404..2607)
                     /locus_tag="KRL22_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1273926.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            complement(2997..3227)
                     /locus_tag="KRL22_003493"
     CDS             complement(2997..3227)
                     /locus_tag="KRL22_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273927.1"
                     /translation="MKPTKEVLPFTIILLAVHSDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(3229..3636)
                     /locus_tag="KRL22_003494"
     CDS             complement(3229..3636)
                     /locus_tag="KRL22_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1273928.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRINDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKKLKELMEEH"
     gene            complement(3995..4444)
                     /locus_tag="KRL22_003495"
                     /pseudo
     CDS             complement(3995..4444)
                     /locus_tag="KRL22_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(4458..5384)
                     /locus_tag="KRL22_003496"
     CDS             complement(4458..5384)
                     /locus_tag="KRL22_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273929.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(5509..6291)
                     /locus_tag="KRL22_003497"
     CDS             complement(5509..6291)
                     /locus_tag="KRL22_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBH1273930.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(6447..7067)
                     /locus_tag="KRL22_003498"
     CDS             complement(6447..7067)
                     /locus_tag="KRL22_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1273931.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(7155..7853)
                     /locus_tag="KRL22_003499"
     CDS             complement(7155..7853)
                     /locus_tag="KRL22_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1273932.1"
                     /translation="MYKLSYVVRVSTKNLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFGATQTLGEHEDIYLGYNLDTGKNVYLK
                     PALASQGVKGSITNALASAFIGSLGGGKLFSNNMLVYYAVLFGGQAVIVDPKAKRGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKKDSESLAIDILTFLTGISSRDSD
                     KFLQKNDNWKIIME"
     gene            7954..8769
                     /locus_tag="KRL22_003500"
                     /pseudo
     CDS             7954..8769
                     /locus_tag="KRL22_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            9439..10206
                     /locus_tag="KRL22_003501"
     CDS             9439..10206
                     /locus_tag="KRL22_003501"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBH1273933.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
BASE COUNT         3515 a         1566 c         1558 g         3572 t
ORIGIN      
        1 gaatatttta ttacaagggg gattttaata tggaatacga tatgccactt tacagaccac
       61 caagtgaggc ttatagtctt ataatacaag tcacactagg atgttctcat aacaaatgta
      121 cgttttgtag tatgtacaaa tctaaaaaat ttaaaataaa gccactagaa gtaataaaaa
      181 atgaaattga tatatttaga agatattata agcatgtaga aagaatattc ttagcagatg
      241 gagatgcatt gataatacca atggagaaat taagagatat tattttatat ataaaagaag
      301 tttttccaga gtgtgaaaga attactatgt acggctctcc taaatctata gagaaaaaat
      361 ctgatgatga acttaaagaa ttaagaaaac ttggtgttaa aatgatttat ctagggcttg
      421 aaagtggaag caatgaagta ttagaagata ttaagaaagg ttttagtagt gaacaattaa
      481 taaaagttgg tagaaaagtt aaaaaaagtg ggattaaatt atcagccact gtaatagcag
      541 gtcttggagg aactaaaaaa acacatcagc atgcagttga tacaggaaaa atgttaggag
      601 caatttcacc agattatgtg ggtgtactta gtttaatggt agaacctaat actgaacttt
      661 acgatttact taaggcagga gagtttacaa tactagagga taaggctgtg ttacaagaaa
      721 ttaaagagat gataaagaat atagatgcta atgaaaaaat tgtatttaga agtaatcatg
      781 catcaaatta tgctaattta aaaggtgtat tacctgatga taaacaacgt ctaattgatg
      841 aaattgatta ctatctaagt aaccaaaagc taaaaagaga agaatataga agactatagt
      901 ttttgatata tcaatctata ttgataggta aatactaaga ttatttagat acaaaaaatc
      961 atgctacatt aatagttgct tactattgat gtagcatgat tttttattaa aaaacaaaat
     1021 ggtatattca tatataatat atcaataata atgaaaatgt gaactagttt aatagaattt
     1081 tacctattat aataaaaaca ggaatttaaa taataaaaag taaagtaact ttttattaag
     1141 taactttact ttttatttta tttaatgttg tattaaattt atatatatta aaataatata
     1201 caaattttga aaaagctctt ataaaatgat tattaaagta aagtttaata taaataaatt
     1261 ataaaatatt aaactaattt atcaatattt cctgattgaa tatgcttaat gtttgattga
     1321 atttttttat atggccaatc ccaccattta atttctaata attttgaaat tgtatcatta
     1381 ttaaatctct tttttataat ttttgcaggt actcctccaa caatagaata cggtggaacg
     1441 tcattagtaa ctactgctct tgttccaata attgcaccat caccaatatt tacacctgac
     1501 ataattatag aatcataacc tatccacaca tcatttccaa ttataatgtt acccttattg
     1561 tcccaagcgt ccgttatatg gttgatatcg agtttccatt cttcataaaa gatgggaaaa
     1621 gtatatgtgg attttgattt cattgagtga tttccactag tcattagaaa ttttgcatta
     1681 catgctattg agcaaaactt accaattatt aatttatcat tgtttatagg gtaatgatac
     1741 aatacattgt ttttctcaaa atctcttggg tcattataaa agtcattata tattgtgtaa
     1801 tctccaactt ctatattttc ccttgttatt acatttttaa gatatacagt ttgataatca
     1861 ttacttcttg gatatacctt atttgaactt ggaatagtca tatttaaatc tctcctttaa
     1921 tatatattat gtttttgact attccactac tacaatacat ctcttcacag aatcactcct
     1981 tgttaagaat cttcataaga taatggcgtc cttttttagt gttaagtcgg atattctttc
     2041 ttagtacatt ctttttagcg tataactgac aaactgtcat tttcttacca atagtgtcaa
     2101 tgctatcatc aaggtcattt tgtattgctt tttccttatc ccttaatgat atatcatcac
     2161 gttttccctt tgggggttta tcagtaggta caagtttcca agagtaaaca aattgtggtt
     2221 taccaaatga atatacatac ttatatgcgt atcttccatc ttttctctgg ctctctccag
     2281 ttcttaaaat tctatcttta ttatctcgtc ttttttcagt tgacatgata agaagctcct
     2341 ctcaataacc gaattgagct tgatacgtca tatgaatatt ataacatata aggctcaatt
     2401 tcattagata aagtcaagtg tatcaacgat tttctcaaat tgttttctct ttatttgaat
     2461 gcgattgcta ttcataatga cccagccaga atcaaggttt tcatcagcaa gtttacgtaa
     2521 ttttttctct ccaatacgaa agtattttga cgcttcttca atcgtcaagg tatatttttc
     2581 ccaaataggt acatcagtat tgttcataga atgtatcact cctttatatg ttcgtagttc
     2641 agaagtagat agatggcttt ggtaagctcc attggtattt caaccaatcc cattcttatg
     2701 ggcagaaccg tgtcatacag gtgtatcatt atactgtggt acaggttacg gcaaaacaac
     2761 cgttccaaag gttattcaca aatcactata tagtagctct cttgattaag gtcatggcgt
     2821 atagtatttg ttggctatct gtatcacaaa cgtatctatc tactttattc agttgtcaaa
     2881 gaacagtcgg cattgatttg cctataaaaa atcacaatag cttgtgggct tttatagaca
     2941 aataattagt gattctccat gtaccaaata gcttgataca tggagagagg gcgagattaa
     3001 gacaaattaa atctcaaaat agcagtgatt agttttgttc ctagcattcg ctttgtttct
     3061 tcttctacat gaatataggg atttccgtat tcatcaaata aagttttctg tgaaagacga
     3121 atgatatagt gttcaaaatg tttaagtatt ccgtttattg catttacatc gctatgtaca
     3181 gcaagtaaaa taattgtaaa aggtaatact tctttagtag gtttcatttc aatgttcctc
     3241 catgagttct ttcaactttt ttagtgcatt tgttttgtga taatgtatgg tattttctgc
     3301 taaatccatc aatgttgcta tgtcagcatt tgtcatgttg agaaagaatg aaagtagaat
     3361 tatatcttgt tttctttttg taagttttcc gattgcttgt gccattaata catcttcaat
     3421 tcgtatgttg tagtcgtaag aaaccataca gatgtagtta gaatcataat catctaaaat
     3481 actcaattta cttaattctg caagtgacaa agattcgaga gataccaaat aatcatttat
     3541 gcgtttattt tcgtcataaa tatctctagc atagttacgc aaaactgttt tacagaaact
     3601 gtcgaattga tgttcaattg tcttttcatc aaccataaga tttcaccctc tttccatcgc
     3661 aaggagttaa ataaccttgc ttactcctat cacggtggga gggcgttaaa tcttcgataa
     3721 atttcaaaaa aagagaaaaa aatacacact ctgcctatag ggcaaaaatg tgtattcttt
     3781 aaaacgtatt taatttatat tggttgtaag ccaccaccat attgatgtat ggaaatatgc
     3841 attggctagc ttttcataaa aatacaaaga tgcataagaa attaatagag gggaaaaact
     3901 tattctgtta ttaaaaagta ggttaattct aataaatgct attgcggttg aattaaacta
     3961 tatacatggc aatcaatcat gtttctattc tttattatga attgtgacag tattcttcaa
     4021 tcttaaaacc acatttttcc aatactttac ttgaccctct attgtaggaa tatacattag
     4081 catgaatttt gttaaggttt tatttttcaa aggcaatttt gcatatttct tttactgcat
     4141 ttgttgctat ccctttgccc caatagttcc tagcaagcca gtaacctaat tcagcatttt
     4201 tattaataga ggtatcttct tcaaatgtta ggctgatact tccaatagcc ctttcttgat
     4261 aaaaaatagc atagctaagt tgtttaacat ctggagttgc caaacaaaaa ctaataaaat
     4321 ctctagcgtt ttgctcccta taagggtggg ggaagttgtc acgaagattc tttgcaattt
     4381 ctttatcatt cgcaaactca actaaatcgg taatataagc ataattccac tctataagtt
     4441 ccatttttct tctcctttta tgaaacagct acaagaaatc tttctaagcc aataccactt
     4501 atcaaacagc gttctttttt atttccaagc atttgataag tccagtcaac aaatccaccg
     4561 tcaactattt caacggtttc atttccttgt ttgaccgata atttgaaatt gataccttta
     4621 taataattat tatcaacatc atcattatga attgataact ctatattagg aaaaataagt
     4681 ttgatagttt caaccattct gtcgaaaaat ccgtcattat ctttgtatcc gtttcttttg
     4741 cgtagaataa tagagaaacg aacattttct atttcactta atatatcttt ataatagttt
     4801 aagtgctttt ctaacaacat tttttcacaa gtgtaagacc ctgtatctat accagatgaa
     4861 accatacaat ataagccaaa atgtgaatat aaacctttac ctacaaaatt ttgtgctctt
     4921 attaccctag cagtagtagc catgtggata ggtatggtat tattttcttc ttttcttttt
     4981 aatttatcag caataattat tgccaacata tttgaggggt ctgcaagtgt ttctgtccct
     5041 cgtagagcac ttactacatt atattgatct acggagccaa aaacgctaca gctacctaat
     5101 ggagcagagg gagaaagcat aatcgtcttg atatccatat tgaatgcttt tctcaataat
     5161 tttgactcca aagcatgaat ttcttctgga tctataccgc tagggatagt aaatctattt
     5221 agttggtatg actttagaat atcagttgca gttaaagtat ttgcttgtct atcaaacact
     5281 tctaatagaa gtgagttcaa atctgatttt gatagagctg ataacttatc aactatattc
     5341 ttatccccaa ttttatttgt aattctactt aaaatatcac tcatagttat cctccatact
     5401 gttactttca aaataattat agaattgtta caacaactaa tctaggtcat ttgaccaaaa
     5461 atgaaaaaac actgaatatt tactattcaa tattttttta ctttgggttt atttgattaa
     5521 atcttgaaaa tactgtaatg caaccctttc agcttcaacc tttcggacaa taggactttg
     5581 tgataattcc tctcttaact caagatacag gttgatagta gcctgcaatg cattaacaca
     5641 gcttttatat tcatggttag caaccgtctt ttctaatgct tcaatatatt ggggtgcgtc
     5701 caattcaatt tttctaactc cacgaggtaa tttacctaag agaagctgta ttaatggggc
     5761 aagtactgat tgtcttaaaa aagataaaaa atcaattgtt tcaaatagtt ctctacgtcc
     5821 aatcttagtg caagcgtaat gaacccaaat ccaaaatcta tcttcaatcc actgtaagtc
     5881 tggagttggg aagtatgctt cttttttaga ataaatttct gttatgcagt tgttttcttc
     5941 atagagaata gctgaatctt caaccctatc tagtaaacca tctaaggttg taaacttaaa
     6001 atcaacatga agaacagggg aatcatagag ggaaattatc aatcgaggtt ctccaacgtg
     6061 ttcgccagta aaagcagaaa ctaatgttcc aaactgttcc acaataagta atctctcttc
     6121 gataacttct tcataggatt tatcatctgc tacaatcaga aaatccaaat cagaatattc
     6181 atctaacgat tttgtgatat aagaaccgct aattgcaagt cctattatcc tactatctct
     6241 ttttgaaaat tctaatacgt tttgtatcat tttctgttgt gttttagtca taatataaca
     6301 cctctcactg tcttttatta gctatcaatc caacataatt atgcatagga gtattatata
     6361 atgaagaaat aaaaaaaaat aggtcacttg acccgaaata aaaaagcatt gaataattat
     6421 tattcaatac ttttttgaaa ttatacttat gttgtaggaa gattctttaa tacctctcgc
     6481 tgattaatta cactaaatct tttgttttca taagcaatta gatgttcttg tacacattca
     6541 tttatagcac gattaatgct tctaattgga gcgtttactt cgctagcaag ctgttttttg
     6601 gtaagcagat ttaattcact tctataatag tgtaaggata tacacctcag aagtcgttct
     6661 ttaacactta aagatgataa ttcttcaatt aattcagcat ttacaactaa tttactagat
     6721 atttctcgaa tcagaaattt tgtagcttca aaatctcccc ttaaccagtt taaaaaatca
     6781 tctctatgaa gtttatatac attacaatct gtgaaagcga caatttcaac gggttttttc
     6841 ccatcattaa attgttccat ttctccaaaa aaactaccac ttctataaag atgaatcgtt
     6901 gagatgtttc ctttcacatt taagatgaat gcttctgcaa taccgtcaat cataagaatt
     6961 acatattcat tttcttgctc agcaaaaaga atagtctctt tctttttata cgttttttta
     7021 acaagcttct ttttaatatc ttcattcata aaatcaatta aatgcatatt catccctcct
     7081 taccaaatct ttgattaaat tatatcatct ttcaattagt taggtaagat agtaaaaata
     7141 tatttacata gaaactattc cattattatt ttccagttgt catttttctg caaaaactta
     7201 tcactgtcac gactggagat accagtaagg aatgttagga tatcaatcgc taaactttca
     7261 gaatcctttt tacggctcaa aatgacgtaa gggtcaagca accctttgtt ttcatcatta
     7321 ctggttaaat tgacaatgtt tatctcatgg gctatttctg gtagcgtttc tttccatttg
     7381 ccgcgttttg ctttagggtc aactatgacc gcctgtccgc cgaatagtac cgcatagtaa
     7441 acaagcatat tgttactgaa taatttacca ccacccaatg aaccgataaa cgcagacgct
     7501 aacgcattgg taatagaacc ctttacccct tgactagcaa gggcaggttt tagatagaca
     7561 ttctttccag tgtccagatt gtagccaaga tagatatcct catgttcgcc aagggtttgt
     7621 gtcgctccaa aaccaagtcc agccaaaaaa tccgaagtga catattgaat ataatcattg
     7681 atgtaacgtt tgctgacagg aataaattcg ccatgcaatc ccaacatatc cccaaaggga
     7741 cgcacgagct tgattgataa gtcgtcgtaa aagtctttga cttcatcaca acgccttttt
     7801 agctcgtcaa gattctttgt agatacacgg acaacatagc taagtttata catagattct
     7861 ttacagttaa aagtctgttt ttaaaaaaat gtataaatta taaatcaaaa tatagatact
     7921 atcaatgacc cactaggtgc aaaaagcatt gatatggtta aattatcaga cgctaaaagc
     7981 tgggctatcc gaatgagtga agatgggtgt gcttataaat ccattgacaa ttataagcgc
     8041 tcactgaaag cgtcgttttt catggcaatt caagacgact gtattagaaa gaatccattt
     8101 aatttttagt taagtgatgt tttggaagat acaacagaac caaaaatcgc tctaacacca
     8161 gaacaggaaa tgggcttatt atcctttatg gggagcgata agacttattg taaatattat
     8221 gatgatgttg ttatcctctt agaaacagga ctacgcattt ctgaattatg cggtttgact
     8281 ttagaattgg atatgaaaaa taaagccatt atggtagacc atcaattgtt gagtgatact
     8341 aagattggct attatgtaga agttccaaag accacacagg gtaagcgaga aattccaatg
     8401 actgaaagag cttatcaatc atttgaacgt atcgtggaac ggcgtaagaa cgctaaagca
     8461 gaaccaatca ttgttgatgg ttaccagaac ttcctatttc ttaaacaaga tggattacca
     8521 aaacaagcaa ctcattatca aagcatgtta agagcgttag tcaagaagta taacaagacc
     8581 catgaggaca agctaccaaa gattacgcca tatatcttta tgcatacact ctgtacaaat
     8641 atggctaaca aaggaatgag tcctaatata ttgcaatata ttatggggca taaaaacatt
     8701 actatgacgc ttggctatta tgcacatggt tcatttagtt ctgcgagagc tgaaatggaa
     8761 cggttataag cctagtagta tgactagagt ttactactta tttactactt ttgatggcat
     8821 tcttatacgg ttaaatgcca acttatgcaa agtatcttcc aaagagaaaa tgccgatact
     8881 ccttgtagat acaggatata tcgacattta ccaacttatg aaaagataat caaatttaat
     8941 ataagttttt caaataaaaa gatactaaat tctttttaga gaatctatat aacattactt
     9001 aagcttggtt ggggtataaa caattgagta gctacttttg tatggtgttc aactttagtc
     9061 aaaactctta aataatgcaa atgatttaga ttcattaata ttcaatctct tcataagtag
     9121 tgaaattcga gttatttctg cataattata ctatgattta tagattaatt ctattagcat
     9181 ccagaataat attgtttata tgagtaaaat ttaaagaata ttgtgaaaat tatagaatgt
     9241 taaaataaat ttaggtaaaa aaagtgtttg tatattatag agtacctttt ctaaaatatg
     9301 tgggattgtt ttaagaatta gaataaaaat tatttttaaa ttagtatttt tataatgtat
     9361 agtattttta atgtataatt aaattgtgca gaaaatagaa tttaaagtcc tatagaattt
     9421 ctgattatgg aggagaatat gaaaagaaaa gttcaagtaa aaaatattac tattggagaa
     9481 ggtagaccta aaatttgtgt accaattatt gggaaaaata aaaaagatat tataaaagag
     9541 gctaaagagt taaaagatgc atgtttggat attatagagt ggcgagttga tttttttgag
     9601 aatgtagaaa atattaaaga agttaaggaa gttctctatg aattaagaag ttatatacat
     9661 gatatccctt tattattcac atttagaagt gtagtagaag ggggagaaaa attaatatca
     9721 agagattatt atactacttt gaataaagaa atttctaata caggtttagt agatttaata
     9781 gatgtagagt tatttatggg agatgaggtc atagatgaag tagttaattt tgctcataaa
     9841 aaagaagtga aagtaattat atctaatcat gattttaata aaactccaaa aaaagaagag
     9901 attgtatctc gtttatgtag aatgcaggaa ttgggcgcag atttacccaa aatagctgtt
     9961 atgccgcaaa atgaaaaaga tgtgttagtg ctacttgaag ctacaaatga aatgtttaaa
    10021 atttatgcag atagaccaat aataacaatg tcaatgtcag gaatgggtgt tataagtaga
    10081 ttgtgtggtg aaatatttgg ttctgcattg acttttggag ctgcaaaaag tgtttcagca
    10141 ccaggacaaa tatcatttaa agagttaaat tcagtactta atctattaca taagagtatt
    10201 aattaaatta a
//
LOCUS       DAEPUT010000119        10183 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.123, whole genome shotgun sequence.
ACCESSION   DAEPUT010000119 DAEPUT010000000
VERSION     DAEPUT010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10183
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.123"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(14..1768)
                     /locus_tag="KRL22_003502"
     CDS             complement(14..1768)
                     /locus_tag="KRL22_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HBH1273934.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKAIRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            complement(1986..2876)
                     /locus_tag="KRL22_003503"
     CDS             complement(1986..2876)
                     /locus_tag="KRL22_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1273935.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            3025..3885
                     /locus_tag="KRL22_003504"
     CDS             3025..3885
                     /locus_tag="KRL22_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1273936.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            4341..4907
                     /locus_tag="KRL22_003505"
     CDS             4341..4907
                     /locus_tag="KRL22_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1273937.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            4947..5528
                     /locus_tag="KRL22_003506"
     CDS             4947..5528
                     /locus_tag="KRL22_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1273938.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(5585..6502)
                     /locus_tag="KRL22_003507"
     CDS             complement(5585..6502)
                     /locus_tag="KRL22_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1273939.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIEVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            6632..8263
                     /locus_tag="KRL22_003508"
     CDS             6632..8263
                     /locus_tag="KRL22_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1273940.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            8266..9213
                     /locus_tag="KRL22_003509"
     CDS             8266..9213
                     /locus_tag="KRL22_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBH1273941.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(9498..9761)
                     /locus_tag="KRL22_003510"
     CDS             complement(9498..9761)
                     /locus_tag="KRL22_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HBH1273942.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(9860..10105)
                     /locus_tag="KRL22_003511"
     CDS             complement(9860..10105)
                     /locus_tag="KRL22_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273943.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
BASE COUNT         3553 a         1471 c         1419 g         3740 t
ORIGIN      
        1 ttttcatatg tttttattct ccaattgata tattatttat gccattattt ttaacttcaa
       61 taattggttg tccatttcct aaaatataat ctttagacca accttctggc aatttattta
      121 tcccatttcc aattaacttc aagtgtaaat ttgatggttc ttttttcaga tttaatttaa
      181 atattccatc aaaggtacct ttattatcgc ttccaaataa acttatattg ccatttatat
      241 tcgtagctgt tacatttaca attccattgt ttgctctaaa ttttatttca gatgatatag
      301 tttcagctgt tacacctgaa atcccactat tagtatttat attgaaagga tttgttacat
      361 tgttatcaac aatgttagca atcccgtcat tgacatcaac agtagctcct cctttaatat
      421 tataaagttc tactgaacca ctttcaacat ctactttaaa attagaatac attttatcag
      481 gaactccaat ttttatcaca tttaccatcc tatctttatt tgcatttatc atattgtcgc
      541 cattcatatc ttgcaaatca ctatctttct tatctatttt tttcttagca cttacaacta
      601 gctttccatt ttttatatta ttagaagaat tttctttata tacagaaaaa gtacaatttt
      661 tttcattagt tacacttacg taatcaaact caaatttatt ggtattcgtc ttttcaacaa
      721 ccacacctaa attatctgat tctataagta tttcagaaac ttcatttcct tcaactgaag
      781 ttaagtgttt taaaatattt ggagtcatat ccatattatt atatttaatc atatctaaac
      841 actgtttata tatattggca tcaatacctc caacttttgt tatactttta gctcctttta
      901 aaataccttt attacttcca tcagcaacta aaacgattgg tttttctttg gctaaaggag
      961 ataatgttag tgcatctact aattgatatc catttgttat ataaaaatct gtagctccat
     1021 tataaaactt ttccattacc tttttattgg tctcaaatct atcatttcct ccgattctaa
     1081 ttgctttagt ttcatttact aaatcctcat ttatcgcaga tttgccacct atagcgtaaa
     1141 catttaaacc ttcagtctta aatggaactg atttcccatc tgtaagtatt atagctcctt
     1201 tattttttgc aactacaggt gctatactca tagcatcagc ctctcctaca aatccatttg
     1261 taagcattac ctcttttaca ctacttactt catttatttt tttagctaca ttataactag
     1321 tttcaattct attgttacca tttattcttt ccacttgaat accttttctt tttatatctt
     1381 tttctactga attttcaata gtattataac caccaattat atatactttt tttacaacat
     1441 ttaaactctt attatctagt ctatttaaag tagcttttgg tatttcactt tttttagtca
     1501 aaagtattgg tgcgttaata gctccagcta atccacttga tgaaagccca tcagataaat
     1561 ttttatctcc attaactaat attacagtat cataagtttg tctatctgct ataagtcctg
     1621 ctgtttcata tctatcaatt cctattattg aatcttcttt aatctgtgca tttgcagtta
     1681 aattattaaa aagaaacata gtcaaaacta aaattaatat acttagtttt ttactgaatt
     1741 ttttgaattt tttattcata atatacacta ttcctcctgt aaattaaggt ctttaatttg
     1801 cttataaatt atccccttat ttacaaataa taacataata ttatagtaac gtatatatta
     1861 ccttaaaatt atcagtaact ttatatcaat catcttagct tatttatata aattttttta
     1921 tattactttt caaataacag tcatactaaa acaatttcat catataattt gaaaattatt
     1981 actatttaca cagcttttat catcatctta ccaccatcaa atatatattc aaccatatta
     2041 ttctcatata aataagttat ataagaacgt attgtacttc caaccaacac atattgatta
     2101 gcatcaagct tgacattgta caaatcacac attttttcaa taacttcatc aatcataact
     2161 ggctcataac aaaccttttt aatattatct attatttctt ccatcttctt cttattaata
     2221 ttaatcaaac tttttatatc tgtagttttg acagagtgac ttggaacaaa gaaatcagcc
     2281 tctaacattc tcaatttttc tagtgtctta aactgtgaat ctatatccag taggaagaaa
     2341 aaatgatatt tagtaattat attctctggt gtaagactat ctgcaacaaa caaaacatta
     2401 tctggagttc taacaccaat catttcaaaa taatgacctg gaagagaaat cgcttcaagt
     2461 tctgtatcta caattttgcc atttgaaggt ataatataat caacttcact ttcctttgct
     2521 aataaaaatt tattcttcag tgctttactt ggatagccac catataaaaa tgctgattct
     2581 aatattggat tttctgtaaa atatccttca attttagtcg tagcaatctt gcattttgtt
     2641 tgattcttca aatatgcatt tcctcctata tggtctgcat ttgaatgagt gtttattatt
     2701 aatttaggat ttaaattatg ttcttctaat aatcttaaaa cttgtctagc tgtatcctta
     2761 ttatttccac tgtcaattaa aattgcatcc ttaccatcta cgtatacacc tactattgta
     2821 gggagtggaa tataatatgt atttcctttt atatgttcta gagttaattt agccatttta
     2881 taacctccct ttaaatttac ttttaattat agcattaatt ttctgaaaat tccaatcaaa
     2941 ttgtttttat aatatatttt tatttctttt attaaaaatt ggaaaaacta tataatatat
     3001 attataatct atatataagg agtgatgtta ttgaaaaaag atagaataac tttttcagaa
     3061 attttaatat taattgtagg ctgtatatta atggccattt ctcttaactt attttttaat
     3121 ccacatgcaa tcgctgctgg tggtataaca ggacttggag ttgttttaaa ttcattattc
     3181 ggtgtagaac tttggattgt caatttactt ttaaatgttc cattattcat atttgcttac
     3241 aaaatacttt caaaaaaaga ttgttttaaa acggttttag gaataatttt tcttaccata
     3301 gcacttaagc ttactgcaaa tatggctaca ttagatataa caaatgatat gtatcttgca
     3361 attatatctg gttctatttt aatgggagtt ggtcaaggac ttatttttag aataaatggc
     3421 tctacaggtg gaactgattt aatggcactc ctactaaata aatattttcc tacatttagt
     3481 atacctgttt taatgggtat tgtagactgc gttgtagttg ttttatcagg tatagtaaat
     3541 agacaggttg aaattgcact ttattcaact gtggctttat acattttagt aaaagttagt
     3601 gacttgctta ttgaaggatt taattattcc aaatcattca ctattatatc tgacctttca
     3661 aaagatataa gtaaaaaaat aatggaagat ttagatagag gtgcaactat tctaaaagga
     3721 gaaggtgcat atactggaga aaataaaaat gtacttttag tagtagttga aaagaaagaa
     3781 gttgtcgaat tgaaaaaatt agtaaaaaat gtcgacccta atgcttttat tataattaca
     3841 gatatacatg aagctttagg taatggattt aaaaaaatag aataactaac aaataaatag
     3901 caagtataat taacatatac aaattcaact ttttatatgt tatattatac ttgctattta
     3961 tatattatac tttctattta tatattataa ttgttgtttt taagataaaa attaaatgta
     4021 tcaattattg ttttatacaa gtatttccaa atccgttctc atttagatag tatacttaga
     4081 aattttagaa ttattgagtc taactttatt acttacttca ctttataaca atcaaataca
     4141 aatttaaata ttataaaact acaaaataat ttaaagcata taatgtcaat atgtttaaat
     4201 tataaaatat tcatgtagtt atataataaa taatttataa atatagccaa cttagcctaa
     4261 atacgtatat aatatagcta atatggttct tatacttgat accatcaata aaactaaaaa
     4321 tataaaaagg agaacttaaa atgagtgtta gtttacaaaa aggacaaaga gttagcttag
     4381 taaaagataa taatcctgta aaaaatctag tagtaggctt aggatgggat atgaataaat
     4441 tgggtaaaaa aaattatgac ctagatgcat ttgcaatagc attgactaac caagataaaa
     4501 tgaatgttag aggtgacttg gtttattttg gaaatcttaa acacccttct aaagctatta
     4561 tacacactgg agataactta actggaaaag gtgaaggtga tgatgaacaa ataattgtta
     4621 atttagaaga catacctgaa tatgtacata aaatagtttt tggagtttct atatacaaag
     4681 ctaaaaaaag agaccaggat tttggtcaaa tgaacaactc ttttataaga ttaattgatt
     4741 caaattccaa gcaagaacta tttaaatata atcttcaaga agacttttct ggtaaagtaa
     4801 cagttttggc aggagaaatt tatcgtagaa atgaagaatg gaaatttaat gctttaggaa
     4861 ttggtcaaaa tgaagagctt cgtgaattaa ttaatacata taagtaataa ttacaataaa
     4921 aaatttataa tgaggagttg gtttaaatgg gtataacttt agcaaaagga caaaaagtaa
     4981 gtttaacaaa aagtaaccct ggtctaaaaa aagtaatagt aggactagga tgggatatta
     5041 ataaatatga tggtggcttt gatttcgatt tagatgcctc tgcattttta actggaactg
     5101 atggaaaagt aacgaatgat ggagacttta tattctataa taatttaaaa cacgcttctg
     5161 gagctgttga atatatgggt gataatagaa caggtgttgg tgatggtgat gatgaacaaa
     5221 taaatgtaga cttatctaaa atacctcaaa atattgctaa aatatcattt agtgttacta
     5281 taaatgaagc aattacaaga agacaaaatt tcggacaagt tgaaaattca tatataagaa
     5341 tatataatga agaaactaat gaggaactta ttaaatatga attgggtgaa gattttagca
     5401 tagaaacagc aatagttgtg gcagaactat atagacataa tggagagtgg aaatttaatg
     5461 ctttaggttc tggatttgag gatggacttg caggattgtg taaaaatttt ggcgttaata
     5521 taggctaata tatctaaata aaaataagag tatattgata tactcttatt tttatttaga
     5581 tatattataa actgtttaca cttctactct tctttctcgc ttgttttttc ccatattcta
     5641 ctgaaatatc aaaaaatgct gaaatatttt ctgtaaaaaa cttgcttcta tgatatgcaa
     5701 tatcaaatgt cctatgtaaa ttaatacctt caatatcaca agcccacaaa agatgctttt
     5761 ttaaataatc ctcaataagt aattcagata taactgcaat gccaaaatta tctacaactg
     5821 ctcttaatat agcttcagag ttataacatg accatctaat attcattggg atttttaatt
     5881 cttttaattg cttttctaat tgtgctcttg taccacttcc caattcacgc ataattaatg
     5941 gttgatttga aagttctgaa acttctatag agtctctttt ataaaactca tgcttgtgtg
     6001 aacatataag tacaagatta tcattaataa tgctttttgt aacaatatct gggtgcttaa
     6061 tttttccttc tacaatcgca atatctaatt cactattaag taattttttt gcaatcagtc
     6121 ttgtatcttc tacaaatact tcaggttcta taagaggatt taccttgtat aattctaaca
     6181 ttatcgggct tattacacat gtaccaacag ttactgttgc cccaactctt atacggatat
     6241 tttttgcaca atgcttcata caatcattca tttcttcatt tacagctaaa agatgcctcc
     6301 catatccaag aagttttttc cctgcctcag ttaaatataa tttttttgaa attctatcaa
     6361 atagcttaac accatactct ttttctattt ctgaaatagc ttggctaact gatgactggg
     6421 taatatacat atttcttgct acttcactca ttttaccaca ttcagcaacc ttaacaaaga
     6481 tttcaagact acgaattgtc atattatcac aaccttagca aacattagta aatgcttatg
     6541 attttattaa tattttagta ttttacaaat atattgtcaa gaagtataat tttattatag
     6601 agttataaag tagattggag tgtgatatat tgtgaaagta ttaattatag gtggagttgc
     6661 tgctggaaca aaaactgctg caaaaataaa acgtgaaatg ggtgataatt gctctgttac
     6721 aatactaaat aaaggtgatg atatttctta tgcaggttgt ggtcttccat attacgttgg
     6781 taagataatt gaagataaat catctttaat cgtaaataca cctgaaagtt tttctaaact
     6841 aacaggagca gaagttcgtt gtggagttga agttacgtct attgatagaa atgcaaaaca
     6901 agtaactttg aaaacgcttt caacaggaga aaaagaaaat ctaagctatg acaaacttgt
     6961 aattgctaca ggggcagacc caataaaacc accaatacct ggaatagatt tacctggagt
     7021 attctttatg cgtactccaa atgatgctat aaaactaaga gattctattg aaaacggtat
     7081 taagagagct gttgttattg gtggaggttt cattggtctt gaaattgctg aaaatctttc
     7141 tgcaatgggt atacgtgtaa gtgttgttga tatggctgaa catgttatgc ctggatttga
     7201 tactgatttt gctgaatacg ttgaaaatca tatggctgat aaaggcataa tgatttttac
     7261 aggtgaccaa gttgtaggta ttgaaggtga aaataaagtt gaaaaacttc gtactaaaaa
     7321 tagagctatt aaaacagatt tagtggttat gtcagttgga atccgtccta acacaggttt
     7381 tctaaaagac acaggtttag aatttgcccc taataataca attattgcag atgaatatat
     7441 gcttacaaat gacaaagata tatacgtagt tggagactgt gcttttgtaa aaaattcttt
     7501 aacaaataaa cctacatggt cacctatggg gtcatctgca aatcatgagg gtagaatttg
     7561 tgcacaaaat atatctggaa aatctaaaac ttacaatggt gttcttggaa caacagtagt
     7621 aaaattacct gagctcaatg caggaaaaac aggtctaagt aaagaaatag ctgaaaaaga
     7681 aggttataat gtttgctctg taaccatagc tactgatgat aaagctcatt attatccagg
     7741 tgcatctaat tttattataa gaatggttgc tgaaaaaaat actagaaaat tattaggtgt
     7801 tcaagttatg ggacctggag cggttgataa aatagtagat atcgctgcta ctgcaataac
     7861 tttaggcgct gacctttatt cattagaaag tatggacctt gcatatgcac cacctttttc
     7921 aacagctatt cacccttttg tagtggcagt aaatgtttta caaaataaac ttaatggaga
     7981 acttgatagt gttttacttg acgaaattga ggattttgac agttggacta aacttgatgt
     8041 ttcaaaagct ccttctattc ctagtttacg ttatattcct gttggtgaaa ttaatggaga
     8101 aattgaaggc cttgctaagg atgaaaaaat tcttcttata tgtgctaaag gtaaaaatag
     8161 ctatatggcg caaaatcgct taagacgctt tggctataca aatacgaaag ttcttgaagg
     8221 tggaatacta ttttatccaa atcttaaggt aatggaggag taaatatgag taatgttaca
     8281 gcagaacaaa aaaaggaagt aaaaggtaga ggttttctac caagcaggga tggagaacat
     8341 tttgcagcac gtataataac tgtaaatggt gtaataaatg catcacaagc aaaaaaaatt
     8401 gcagaagctg ctgaaaaatt cggaaacggt cagttagcat ttactactag actaacagta
     8461 gaattacctg gtgtaaaatt tgaagatatt gaagctctaa gtgaatttat tgctagcgaa
     8521 aatctaataa caggtggaac tggatcaagg gttcgtcctg ttgtggcttg taaaggtact
     8581 gtttgtgttc atggtctagc tgatacacag gcacttgctg ctgaaataca cgaagaattt
     8641 tacaaaaatt ggtatgatgt aaaactacct cataagttca aaattggtgt tggtggatgc
     8701 cctaataact gtattaaacc tgacctaaac gatcttggaa ttgttggtca acgtgtacct
     8761 gactatgatt cagagctttg tgttggttgt aaaaaatgtg ctgttgtaga ggtctgtcct
     8821 gttaaagcag ctaaattaac agataaaggt aaacttgaaa tagatagtaa tctatgtaat
     8881 aactgtggta agtgtataga aagttgtaat tttgatagta ttgaagaaaa agaatctggt
     8941 tataaagtct atataggagg gaaatgggga aaatcagttc gtcctggaac acagattgat
     9001 agattatttt caaaagagga acttatgact ttaattgaaa aagcaattct tttatttaga
     9061 gaacagggta acacaggtga acgttttgga ataactatcg atagaatcgg tgctgataaa
     9121 tttatagaaa tgcttttatc agatgaagtt ttggaaagaa aagaagagat actagaggct
     9181 cttttacacc ttacaggtgg agctgtatgc taacaataaa tattttaatt gtacagataa
     9241 cctatggaaa aaattttagt taagaataat taaaattcta tatatgatat atgataaatg
     9301 aggctatctc aaaacacaga tacgcctctt tttcattgtt gaaatgataa agtatattta
     9361 agtttataca aaaaagagtg tctcgtgaat tataaaattc attttgaggc acccacatta
     9421 ttttataata attgcttatt aattttattt taactatata aaaagtacaa aaagtaagaa
     9481 tatccaatat tctaaaatta attttgaatt gtattgattg aaaagtttac tattccacta
     9541 tttccatctt gatttactac tagataccat gttccagtat taggaactct cattctacat
     9601 ggatttttct ttgcaaatcc accatagtaa tcataatttc tttgattttt aaatttcaca
     9661 taatttatat ggtctaacaa tattacattg gcttgtttct ctaaatttac ctctacaata
     9721 tccccttttt ttaagttcat cttactataa ctatattcca ttgaattact cctccagtat
     9781 cgaataatct ttgttattta ctcatctcaa atatgtaaaa attcatttaa aatattacaa
     9841 atactatata attagactat tatccagttt taaccttatt tactacaatc caaaggttat
     9901 taaaaatatt attggcaaca acttctccat cccatacaac tctttcttct ttattttcta
     9961 ataaagcata gtacccagag tcagaacttt catctttata gactgtaaca taaaactctt
    10021 catcactata ttcaggtata tttttaaagt cttcagatat tttacatgtt aatatataac
    10081 cttctaattc ttcatctata aacaaagcaa ttcctccaat ctctatattt ttactaatta
    10141 taccatatta tgtcataaac tttttatttt attacaaatt tct
//
LOCUS       DAEPUT010000120         9831 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.124, whole genome shotgun sequence.
ACCESSION   DAEPUT010000120 DAEPUT010000000
VERSION     DAEPUT010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9831
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.124"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            288..1304
                     /gene="gap"
                     /locus_tag="KRL22_003512"
     CDS             288..1304
                     /gene="gap"
                     /locus_tag="KRL22_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH1273944.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            1686..2855
                     /locus_tag="KRL22_003513"
     CDS             1686..2855
                     /locus_tag="KRL22_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273945.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            3236..7489
                     /locus_tag="KRL22_003514"
     CDS             3236..7489
                     /locus_tag="KRL22_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH1273946.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            7638..8132
                     /locus_tag="KRL22_003515"
     CDS             7638..8132
                     /locus_tag="KRL22_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH1273947.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            8248..8625
                     /locus_tag="KRL22_003516"
     CDS             8248..8625
                     /locus_tag="KRL22_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBH1273948.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            8831..9271
                     /locus_tag="KRL22_003517"
     CDS             8831..9271
                     /locus_tag="KRL22_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HBH1273949.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
BASE COUNT         4010 a          990 c         1733 g         3098 t
ORIGIN      
        1 ttgaagatat attattttta aaaataagta tagtttaaaa attcaaaaaa aagatggcaa
       61 aatatgtccc aagggacatt gagtaaaata aatgatttca gcttctttac actaaaaagt
      121 acatactaaa tgaggggtaa aataaagaaa aatgatatac taattgtctt ttgataataa
      181 aaaaacatgg aatttgatta tttaatcaag aaaaagtatt gaacaaatga tttatttagt
      241 gtacaataat catgtaaaaa catagtaatg gagggagaca tttcataatg aaaattaagg
      301 taggaatgaa cggatttgga agaataggaa gagctgtatt aagaatagct caagaagaat
      361 taggagataa tatagaaatt gtagccataa atgcaagagc aacaacagaa tctttggcac
      421 atttatttac atatgattca tgctatggaa cttttagagg tgaagtagag gcaaaggatg
      481 aagacactct agtagtaaac tctaaagaga taaaaatatt aagatataat gacccagaag
      541 aattaccttg gaaagaactg ggggttgata tagtaataga atcaacagga ttatttacac
      601 aaagagaaaa ggcagaaaaa catattaaag caggagcaaa aaaagtaatt ataacagctc
      661 caggaaaaaa tgaagatata actatagtta tcggagttaa tgagaaagaa tatgataatg
      721 aaaagcacaa tataatttca aatgcatctt gtactacaaa ttgtctagct ccttttgcta
      781 aagtattgga cgaaaaattt ggtatagtaa aagggttaat gactacagta cattcatata
      841 ctaacgatca aagaatatta gataaaagcc ataaagattt gagaagagca agagcagcgg
      901 ctgaatctat aatacctacc actacaggag cagcaaaagc tgtgtcaaga gtactaccac
      961 aattagaagg aaaattaaat ggtttttcac ttagagtacc aacaccaaca gtttcacttg
     1021 ttgatttagt gtgcgaactt aaagaaaacg ttacatctga gcaagttaac tctgtgttaa
     1081 aagatgctgc tgaaggagaa ttaaaaggtg ttttaggata ttgtgacaag ccacttgttt
     1141 ctatagatta taaaggagat tcaagatcat ctattataga cgctctatcc acaatggtta
     1201 tagaagacaa tatggttaag gtagtttctt ggtatgataa tgaatgggga tattcttcaa
     1261 gaactgttga cttagtaaaa tatgtagctg aaaaattaaa ataatatata tttcttaaag
     1321 caaattttaa aaaaattata taaaactaaa aaaaaagatt atgaaaaata ttgaaggaaa
     1381 aattttttca taatcttttt tctttcatgc aaaaagatac aagttacaac ttatatttgc
     1441 atattaggtc gttagagaag tatatatata tttagtaagg aatcatactt tttataaaat
     1501 gaaagataag atgtcgaaaa cttgcataaa tctgaaaaat ttttattatt aaaatactga
     1561 ttttcatttt aaaaatgata aaaaaatgac aaataaagtt gcaaatagta atacttataa
     1621 gtataattaa aaaagagaaa aggttttgtt aaactttata acaaaaaaag aagggatgat
     1681 tcaaaatgga gaagttaaca gacaggagac aggttaaggc agtaagcatg gaaaccttca
     1741 ttttcctaat attactagta gttggttttg ggtatgttgg tagtattatg ggagcaggaa
     1801 tgatgttcaa agtaataatg agtacagcac atgctttact attggagaca gttttcttaa
     1861 ttatggctat ggcagttctt gcaggcgcat taagcgcact actttcagag tttggagtaa
     1921 tagcgttaat taataaaatt ttcgctgtat ttatgaagcc tttatatgga ctacctggtg
     1981 ctagtatagc aggagctata acaacttatt tatcagataa tccagctatt ataccttttg
     2041 ctaaagataa aacattcaca cagtatttta aacaatacca agttccagca ttatgtaact
     2101 taggaacagc ctttggtatg ggacttatct taacaacatt tatgatttct caaggtacag
     2161 aatatgtact tccagcatta attggtaatt taggtgcaat tataggtagt gtcataagtg
     2221 ttagaataat gttgacattt actaagaagt tttataaata caatccggaa gaagataaag
     2281 caacaggaac attagagaaa aaggatgaat ttagagaaat cagagaagga aatgtatttc
     2341 aaagagcttt agatgcaatt cttgaaggtg gtaaaatggg ggtagatatg ggaatggcta
     2401 taatccctgg agtcctagta gtatgtacat tggtgatgtt attaactttt ggaccatcta
     2461 cagaccctgt tacaggtcaa gaagtttata caggagctgc atatgaagga ataaaattac
     2521 ttccagttat tggagataaa cttggattta tattagaacc attatttgga tttacatcac
     2581 cagaggcaat agcattccct ataacttcat tgggagctgt tggtgcagca atgtctctag
     2641 ttccagagtt tataaagtca ggagctataa ctcctaatga tatagcagta tttacagcta
     2701 tgggtatgtg ttggagtgga tatttaagta cacatattgg tatgatggat gcattaaatg
     2761 ctagacagtt ggcaggtaaa gctattcttt ctcatacaat agggggttta tgtgcaggag
     2821 cagctgctca ctttatattt acactcgtag gataaatgta atcagctaag ataaaaaata
     2881 atatacaaaa aaatggttgt tgatatgtaa taagaattta catatcaaca accatttttt
     2941 tcttactaaa gataatttat aatacataaa cattaagtgg atattagagt taagttatat
     3001 ttatgtaaaa agtaacaaaa atctgtagaa atttatgaca aaatttagta cactaactat
     3061 atgttcttat ttaaaattta aggttagaat taggaattac ctagtagagt aagctttgat
     3121 taataaaaga atcataaaat aaaaatatta gtcataaaga ttataaataa cttacttaaa
     3181 ataaagccat agaacttaca aaaattaaaa aagcatataa atatggaggg gtacaatgga
     3241 tgaattattt catataggaa ttgatgtagg ttctacaacg gtgaaggttg tggtacttaa
     3301 taatagtaat aatatagttc ataaagaata tagaagacat tattctgatg taaaaaaatc
     3361 agttaaagaa gtactaaatg gtatatatga aaaattggga gatataaata ctaccattat
     3421 aataactggt tcaggtggaa ttggaatatc aaaaaaatta ggtgtaaaat ttgttcagga
     3481 agttatatct agtacaaaat caatagagta ttttcatcct gaaactgatg ttgtcataga
     3541 acttgggggt gaagatgcaa agataacata tctaagtgga ggaatagacc aaagaatgaa
     3601 tggaatatgt gcaggtggca ctggagcatt catagaccag atggcatcac ttttaaagac
     3661 agatgccagt ggattaaatg aacttgctaa agggtataat gttatatatc ccatagcttc
     3721 aagatgtggt gtttttgcta aaacagatat tcaacctctt ataaatgatg gagccaatca
     3781 gactgatata gcaatgagta ttttcaatgc agttgtcgta caaactgtga gtgtcctttc
     3841 ttgtggaaga aaaatagaag gaaatgttgc gtttttgggt ggtccattgt actttttatc
     3901 tgaacttaga gaagcattta aaagagtatt ggatttaaaa gatgaaaaca taatcttccc
     3961 agaaaatgca caactttata ttgctattgg cgcaggatta ttatcagtag atgaagataa
     4021 tatacaacta aaatctctaa tagaaaaatt ggatagcata aagaatattg aagatggaga
     4081 agtaaattta ttagaacctt tatttaaaga taaaaatgag tatgaagaat tttcaagaag
     4141 acatgaaaaa gaaaaaataa attatgtgga cataaattca ataaaaagta attgttattt
     4201 aggaattgat gcaggctcaa ctacaactaa agcagcactt attgatgagg atggaagact
     4261 tgtatattct tattataata gcaatgaagg aaatccatta aaaacaacca ttaaagttat
     4321 aaatgaagta tatgatatat taccaaaaaa tattaaaata ttgagttcaa ctgtaactgg
     4381 atatggagaa ggtcttatta aaaaagctct taaaatcgat aacggagaga tagagactat
     4441 agcacattac aaagctgcta aatttttcaa taaagatgta gattttatac ttgatattgg
     4501 tggtcaagat atgaagtgcc taaaaataaa agatggagta attgataata taatattaaa
     4561 tgaggcttgt tcatcaggtt gtggctcatt tttagagaca tttgcaagtt ctttatctat
     4621 gacaatagaa gaatttgcac acgaaggtat ttattctcaa aatcctgtag atttaggttc
     4681 aagatgtact gtatttatga attctagagt aaaacaagct caaaaagaag gtgcaagtgt
     4741 tggagatata tcagcagggc tatcttattc agtaataaaa aatgctttat ttaaagtaat
     4801 aaagattaga gatttaaatg agattggtaa taatattgtt gtacaaggtg gaacctttta
     4861 taatgatttg gtgcttagaa gctttgaaaa actaattgga aaaaatgtaa ttagacctaa
     4921 tatttcagga attatgggag cttttggttc agcacttata gctaaagaaa aatatgaaag
     4981 tggatacaaa acatccttgt tatctaagga agagttgaat aatatcaagc tagaagcaag
     5041 tgtaactaga tgtaaaggtt gttcaaatca ttgtcttctt acaataaata aattttctga
     5101 taatgaaatt tttatttcag gtaatagatg tgagaagggt gaagctattt atggtgataa
     5161 aaaaatagga ttagaaaaga aaaaaccaat aaatttattt aagtacaaat acaatagaat
     5221 ttttagatat aaaccattgg aaaaagaaga agcaaaaaat ggggaaatag ggataccaag
     5281 agtattaaat atgtatgaag attatccatt ttggtttact tttttcaatg ctatgggctt
     5341 tagagttgta ctttcagata ggtcatcaaa acagttatat gaaactggta taactagtat
     5401 tgcatctgaa acagtttgtt atccaggaaa attagttcat ggacatatag aaaatttaat
     5461 tgcaaaaggt ataaaaaata tattttatcc aagtgtaaca aatgaaaata aagaggattc
     5521 aaatgcagat aattattata attgtcctgt tgtaatatca tattctgaag taataaaaaa
     5581 caatgtagaa aatataagaa ataagaacat aaattatata aatccattta taagtctaaa
     5641 tgataaggaa aaattgaaga aaagactata tgatgaatta tcaagacatt tttctgatat
     5701 aaaaataact aaagaagaag ttaatcatgc agttgataaa gctactgatg aacagaattt
     5761 atttaaaatg gagatacaag cagcaggtga aagagcactt aaagaaataa aagaaagaaa
     5821 tatgaagggg attgtgttat gtggaagacc atatcatata gacccagaaa taaatcatgg
     5881 aatgccagag cttataaatt cattagatat ggcagtgctt actgaagact ctatatgtca
     5941 tttagccaat gtacaaagac cacttagagt tgtagaccaa tgggtatatc attcaagatt
     6001 gtataaagca gctagttttg tgagagataa aaactatttg gaacttgttc aacttaattc
     6061 atttggctgt ggattagatg cagtaactac agaccaggtt caagaaatac ttaatgaaaa
     6121 atcgaagata tatactatta taaagattga cgaaggcaac aatttaggag cagctaagat
     6181 aaggatgagg tccttaaaag cagctatgtt tgagagagaa agcaaaaata tagatgtaaa
     6241 aaatataaag gtaaacagga tacagtatgc taaaaataat cagataacga acaaacatac
     6301 tatattagca ccacaaatgt ctccaataca tttccaattc cttgaaaaag ctgttaactt
     6361 aagtggttat aatatagaaa ttctaaaaga tactgatagt agtgtaattg aagaagggtt
     6421 aagatatgta aataatgatg catgttatcc agctataata gttgtaggtc agctaataac
     6481 agcattaaaa tctggcaaat atgatttaaa taacacttct gttactataa ctcagactgg
     6541 tggaggttgt agagctacaa attatattgg attcttaaga aaggctatat atgatgctgg
     6601 atttaaagat gttcctgtca ttgcacttag tgtaaatgga atagaagata gtggtataat
     6661 ggataatata tcactaaaat taatcaatag actctttatg tctgttgttt atggtgattt
     6721 gctgatgaaa gtactatata gagtaagacc atatgaaaaa gttactggaa gtgcaaatgc
     6781 tctatatgaa aaatgggttg atatatgcaa atcttctctt gttaaagcaa aaatttctgt
     6841 atttactaga aatataaaag atatagtaaa agaatttgat aatttagaga tactagatat
     6901 caaaaaacca aaagtaggtt tggttggaga aatattggtg aaattccatc caattgcaaa
     6961 taataattta gtagatatat tagagcgaga aggtgctgaa gcagtcgtgc cagaccttac
     7021 aaatttcttc ttaagttgtg cctttaatac tatatacaaa cacactcatt tagaaggaag
     7081 tagaaagagt agaatgatag gagaggcatt tatatacata actggaatat atcaaagagt
     7141 atataaaaaa gcacttgata agagtgagag attttatgct ccagccaata taaaaaatgt
     7201 tgctaaaagt acagaaccag tagtgtcatt aggtaatcaa actggagaag gttggctttt
     7261 aacaggtgaa atggttgaat tattaaatga aggtgtagaa aacattattt gtatgcaacc
     7321 ttttggatgt ttacctaatc acataattgg taagggttct ataaaagaat taaagaggtt
     7381 gtataaaaat gcaaatataa tacctattga ttatgaccct tctgcaagtg aggtaaatca
     7441 acttaacagg ataaaactta tgctttctaa ggcttttaaa aatatataag atttatattt
     7501 tgatatgtta aaagttaatg aatttaaaaa tatactctat attaagtatc tataaaaaag
     7561 agttatccta ttttttaggg taactcttta ttagttaaaa aattatatgt atactgatat
     7621 taaagggggg aagtaatatg agtttagtat atgatgttta taaatcaaaa ttaggaaatt
     7681 tgtacatatt aagtgaagat ggttttatag ttagtatata cataggagat gaaaaattta
     7741 ataatttaaa aaatgaatgt attaaaaaag gaattgatat aaagagaagt aaggaagatt
     7801 taaaggaagc aataagccag atagatgatt actttaatgg aaaaagaaaa gtctttaatt
     7861 taaatattcg tattgaaggg actgaatttc aaaaatcagt ttatagggaa atgttaaaaa
     7921 taccttatgg agaaacattg tgttattcag atatagcaag aaatataaac aatccaaaat
     7981 cagtaagagc aataggacaa gcaagtaaaa gtaataaaat tccaataata ataccttgtc
     8041 atagagtagt tggcaaaaaa gatattggtg gatatatggg gaatcattct gatttgaaag
     8101 agatactatt aaatttagaa agacagagtt aacttagaaa gaaatgtttt tattgttaat
     8161 atttgatata ataatagtaa aaagaagtat tttttacaaa aacaatgaag aatttatttt
     8221 aatttacaaa aatgaggggg aattttaatg tgtgataaag ttatagcatc aaaatatcat
     8281 gagaagggat ttaattgtgc agaatcagtt ataaaagcat ataatgagga atttaataca
     8341 gatataccag tttgtttagg aagtggactg ggttcagggt gtggggttgc tagtttatgt
     8401 ggtgcagtaa atgcatcaaa tataataatt ggatatgtaa aaggcagaaa ccacgaagat
     8461 gaaagtacta aagctaaagt atatgctaaa gatttaacta caacagtaag aaaagagtat
     8521 ggttcagagt tatgtataga cctaaaaaaa gatttagttg cttgtagaga aataatggat
     8581 ttcgcatatg atagtctaaa ggaaacttta aaaaaagaat tataagaaaa taagctatca
     8641 agtataaatt atttgatagc ttatttttat agtcgatact aaataaatca aatatatttt
     8701 agaattatta tttgtaaata aacagcaaat aattttagga tttttattta atatagtttt
     8761 tatttatatt tatttttgaa tatgttatac tttgtttaaa taaatatttg taatgaggga
     8821 gatgagaaga ttgaagaatc tcaatttact tattaataaa ttatattcaa aaaatcataa
     8881 tgaagcatat aaaacttttt tattcttaga aaatgaaagt ttaaaatcaa atattacata
     8941 ttgttttttt gactcattcc tagaaatgat tgataacgaa aactcatata ttcgaacaag
     9001 gggattgtta ttaatctctg caaatgctca gtgggatatt gataataaaa ttgaaataaa
     9061 tatagatagt atactaagtc atatcgtaga taaaaaacct tctgtatcaa gaatgtttat
     9121 taaatccata cctaatatta caaagtataa agaaaatctt attaatcgca taaaaatgga
     9181 attaagtaat gcagatataa gtatttataa taataatatg aaaccattag tagaaaagga
     9241 tataaacgat acattatcta atattagtta aatattaata tagaaattga atattatcta
     9301 gttacaatta tttataacta agataataaa acaacaatgg tgctaattta tatgtataaa
     9361 ttaattatga aaaatttata taagtaaaat atattaacat aaaggtaaaa ttttgtatac
     9421 taaaagggaa tatttacagt ttaatggcag ttttaaaata ataaattaaa gctgtcattt
     9481 ttatttaaaa atttttagaa aaagtacaat agtgttaatg tgtgaattag ataaggtgta
     9541 tataatagtt tagatgatat gatataaaat atgttgtaaa ttaaatgttt tctttgacaa
     9601 tatatacaca aggatgataa tatctatatg aataaaagat agtgtgtaat ttgataatat
     9661 gtaattataa cattatgata taattacaat aaagtatgta ataatctgta gaaatttcaa
     9721 gctagttatc taagtcggat aactaaatct aaacgaaata cataatgtat taaataaatg
     9781 atgatactaa aatgatacta tttttataga aatttattga ggtatataat t
//
LOCUS       DAEPUT010000121         9778 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.125, whole genome shotgun sequence.
ACCESSION   DAEPUT010000121 DAEPUT010000000
VERSION     DAEPUT010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9778
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.125"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(412..588)
                     /locus_tag="KRL22_003518"
     CDS             complement(412..588)
                     /locus_tag="KRL22_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273950.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(692..1300)
                     /locus_tag="KRL22_003519"
     CDS             complement(692..1300)
                     /locus_tag="KRL22_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1273951.1"
                     /translation="MEKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNVEQRNGLIDFQLDLLLVDITK"
     gene            complement(1399..2223)
                     /locus_tag="KRL22_003520"
     CDS             complement(1399..2223)
                     /locus_tag="KRL22_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1273952.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAKTDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            complement(2401..3294)
                     /locus_tag="KRL22_003521"
     CDS             complement(2401..3294)
                     /locus_tag="KRL22_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1273953.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIRIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            complement(3551..3988)
                     /locus_tag="KRL22_003522"
     CDS             complement(3551..3988)
                     /locus_tag="KRL22_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HBH1273954.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(4245..4394)
                     /locus_tag="KRL22_003523"
     CDS             complement(4245..4394)
                     /locus_tag="KRL22_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HBH1273955.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(4407..4637)
                     /locus_tag="KRL22_003524"
     CDS             complement(4407..4637)
                     /locus_tag="KRL22_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HBH1273956.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVKTNTTPYDLVIE"
     gene            complement(5083..6276)
                     /locus_tag="KRL22_003525"
     CDS             complement(5083..6276)
                     /locus_tag="KRL22_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005343085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1273957.1"
                     /translation="MSEKRRDNKNRILRTGESQRKDGRYAYKYIDTFGKPQFVYSWKL
                     VPTDKTPAGKRDDIALREKEKEIQKDLDDGIDHIGKKMTVCQLYAKQIRHRANVRHGT
                     KQGRKQLMRILQEDKLGACRIENVKLSDAKEWALRMKEKGYGFKTINNHKRSLKAAFY
                     TAIQDDCIRKNPFDFQLNTVLEDDTEPKEPLSPTQEAAFLSFVQHDKVYQKYYDEIII
                     LLGTGLRISELCGLTEADIDLDKQLINVDHQLLKIADVGYYVETPKTKSGNRIIPMSE
                     KVLEAFQRVLNKRKYTQPVILEGYTKFLFLNRNGLPKVAVNYESMFRGLVRKYNKTQK
                     VALPKVMTPHTLRHTFCTTLANAGMNPKALQYIMGHSNINMTLNYYAHTTSETSITEM
                     KRLIA"
     gene            complement(6356..6559)
                     /locus_tag="KRL22_003526"
     CDS             complement(6356..6559)
                     /locus_tag="KRL22_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family DNA-binding protein"
                     /protein_id="HBH1273958.1"
                     /translation="MNNNDVPIWEKYTLTIEEAAKYFRIGESKLRKLAEENPVPDWVM
                     MNGNRIQIKRKQFEKMIDTVDAI"
     gene            complement(6981..7238)
                     /locus_tag="KRL22_003527"
     CDS             complement(6981..7238)
                     /locus_tag="KRL22_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019727567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1273959.1"
                     /translation="MNGTNGNQNDYPENALVPYPVILAASKGDPDAMKMVLQHFSGYI
                     ASLSMRKLYDERGNVYYGVDEDIRERLQARLMRAILTFRAE"
     gene            complement(7219..7659)
                     /locus_tag="KRL22_003528"
     CDS             complement(7219..7659)
                     /locus_tag="KRL22_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016283905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBH1273960.1"
                     /translation="MEPNRREFQKQCAFQSFCKRVLHNEACNAHDEIRRRRKREVSFC
                     DLALHEERQLYTTDKYFQAETAEPTYQMAGKEITPKLLLEAIRTLPEEKRTAILLYYF
                     EGMTDVEIGKMFNTSRSTIQYRRTSSFELLKKYLEEHADEWNEW"
     gene            complement(8132..8905)
                     /locus_tag="KRL22_003529"
     CDS             complement(8132..8905)
                     /locus_tag="KRL22_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273961.1"
                     /translation="MRNIIKTEFLKLKRYSVIKAGIIMTTLSPLLSLFYSTANGGQTW
                     TFDYFMQQVMISNCTLFFPIIIALIAGYIITREYTDDTMKNILTIPIPYKQLLSGKLL
                     ILLLLTISFSLIGCVIALVINIIVGFPGVHFGNLLNMFIRVTGANIGIYISVLPIILI
                     FCCSANNFLGGVALAFVYGYFGTFEGTLLNYYPIKASMILVDPTCGTEYGYTYHIFPA
                     FITIVLTFLISMIILANKKKEPGTLTVGKKKKAVRKKGW"
     gene            complement(8911..9720)
                     /locus_tag="KRL22_003530"
     CDS             complement(8911..9720)
                     /locus_tag="KRL22_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273962.1"
                     /translation="MLKLIKCEFWKLKRKRLLYALMSLSLFFPLILAYMAKAGTGADT
                     TEHYLQTRFDYVYTMMLGYGLVFLLPCLIGIIAAILFFIERDCDTSKNLRTIPVTNTQ
                     LIMAKISMLFIFSVAFCLISTLSVALFCKLFHVGMVYGMTYKIFMSLIFGVLIVAASL
                     PIVFLIIYFNKSFLLSILLAFFYSIFNWGILGTIGTSISAAKIAFLNYFPVICVMNWT
                     SGLMMDNLQKDNLLPEAYAIVPTTCHTIFIMAITVILSLWLIIRFYKKWTR"
BASE COUNT         3152 a         1708 c         1514 g         3404 t
ORIGIN      
        1 taataaagaa ctgtaataaa taagacttta caatgtaata gaaatgctgt aataataaag
       61 gtctgtagta taataaagaa ctgtaataaa taagacttta caatataata gaaatgttgc
      121 aataacaaaa caccataata aataagagtt tgcaatataa tagaaacact gcaataaata
      181 agagattgta atataataaa agtctgtaat ataacaaaat cctataataa ataagatttt
      241 acaatataat aaaaatccta taataaatag gactctgtaa tataataaaa tgctgtaaca
      301 acaaaacact ataataaata agaccctgta atataataaa aatactataa tatagtaaaa
      361 atcatgcaat aataaaaatc tataataata aacctcagca taacaaagac attaatttct
      421 tactaaaaag gccaccacaa ttaacagtga aaaagcaatt gaaagtattg aaaaagtaaa
      481 gtgagaatta gagtcattat tacgattatt aagttttatc cataaaccac atataattgt
      541 acacaacaat aaaattgctg atattactcc tataaatgta aaaaacatta aaattcctcc
      601 cccttattta atgcaagtat ttttagtcaa tgagaatatt ttcaaacgtt accataaaat
      661 aaaaaaatgt acataaaaaa ttaatatagt attattttgt aatatctacc aataataaat
      721 ctaattgaaa atctattaaa ccatttctct gttcaacatt aagaatatca ataccactat
      781 acttgaaaaa agcattagaa cgaagaaaaa gcaactgaat aaatgaagtt atttgatacg
      841 caatagttct gtattcagct tcagtttttt tgttattctg attttcatag tgagccttaa
      901 ttaaaggtag tatctcaaat ggataaacaa tttcttcctg tatcaatata tagggtacag
      961 aaatctttat aaattgacta tgttcaccta taaaatcaaa aaatgcaatt agtatttccc
     1021 ttaattgctg tttaggtgct aaatttttag tatcatgtgt agccttatat tcatccatat
     1081 gacgctttaa aaatttttta atagaaatat taattaactc ctctttagat ttaaaataat
     1141 aattaatcat agctaaattg acatttgctt tagctacaat ttctctagcc gtaatgcttg
     1201 aaacatctct atgtgaagat agtaactgga ttgtggcatt aattaattgt tcctttgttg
     1261 aatctgcttt cataattttt ccccttaaaa gtttctccat aaaaaaatta aacatgttta
     1321 atacacgttt agatactatc atgaaaattt tgggatgtca atgggtgatt agtacttaag
     1381 tatttaagta ctaatcgatt agacttttat aagggggatt tgaatttctg taagataatt
     1441 ttcaggattt atttcattat gttcaccttt atgaccgatt tgtctattta tacctgatat
     1501 ttgataatca ctatttttat ctaaccaata acagaacgat tcatatgcac cagctatatt
     1561 ttcatatgga ccataaacca tagtacatgc catcatatca atttcttctg tctcacgata
     1621 tataaatcca gatttgttct ttccaatctt ctttacaacc attccaactt caatatctac
     1681 accattatct ttgacttctt catcatggta aaaagctatg ttattgttgg attgacgtga
     1741 tacttctata tgttcttctt tgataaattt agatagcttt tcccagagta taccttcaga
     1801 ttggtagtct ggaattatct ctctaagtga tatgatttta taacttggaa tctttttaaa
     1861 gacaacattg taatgaattt catctttatc acagtttata gcttctataa atttatcaat
     1921 tttatttatt ctttgttgtt cctgctttat ttccttttgt atttcattct tttttctatt
     1981 caattcctta attacaaatt catcattcca attatgtacg atatttgcta tttctgcaac
     2041 gctaaatttt gaatctctca ataatacaat tctttgtaat attgaaatct gttcaactga
     2101 gtataatcta tgacctgtat atttgtctgt ttttgcaggt tttaaaatac caagttcatc
     2161 ataataacgc aacatacgaa tagaaatttg tgttagtttt gaaacctctc ctattttaaa
     2221 catgaaaata tgacctcctt ttcacttata atcagtatat attttgtttt tatatacttc
     2281 aagcgtttgt ggaaatacaa ttattttcca gatgttgcaa taaattatag agagtaaatt
     2341 atatttaagt agtaatcgta tcaaatcata gattatctta atttataatt catattaaaa
     2401 ttaccagtct aactcaaatt caaaatcatc cgactttatc tgttcaattt cagaatttac
     2461 cttctgttta aatttattag aagaaatcat atatacaaga aatattaaac caaatattat
     2521 ttgtacatat tgagctatta cacataattt aatagggtag tgtagaagta attgaatgtt
     2581 gaaaaaatag tacatcatat gaactaaccc agctgataaa atgcttctac ttgtattgat
     2641 atatacaaaa ttaattataa agtttaaaag tacaatgttt ggtataaata aaaaagcatc
     2701 aaatagggag tattgtgcca aattatatgg tatttgatta ggtgtaaaat acgaccctag
     2761 ataccagatt ccacaaacaa gccctaaaat aattgaagag cctataaatc caaatctaac
     2821 taataatttg tcaatggcat atcctctcca tccagcttct tgactaagta tactcaatat
     2881 aaaacttgct aatagcatat aagctatttt agaaggtcta aacactgcta tgtgtatcca
     2941 atctatatca gaagttttta cattaaagta atttccgatt attaacgaag taataaaagt
     3001 taaagcaaaa aataatattg ttaatagtat ccattttatt ctaatttctt taaagcttag
     3061 gtatctataa ataaaatctt gttttgcact ttgtggatag attgtagaaa taaaaaatag
     3121 acctacaata gctggtgatg tatatgcaag ataaaaaatg atttctccaa gtattgtatt
     3181 tgtaattccg agcaacgcag gtgtaagact gaatatccag ttcaatacta gcgtaaatgt
     3241 aaagaaatag attaagtgtt tgtttgtatt aaagggggtg ttatatagtt gcattttttc
     3301 actatccttc cgttttataa tgaagtttta atttttatta attgtttatt tatttttata
     3361 tgtattaagt tatcgcttga tgttagttat tgcctataat aatatcctat tttttatatt
     3421 ttgattaatt atttttacac taaatataat taattagtat ttaatattga atatattata
     3481 ttattattaa ttattaaata ggtcaataaa tttgcaatta gtgatattaa taaattactt
     3541 tagattttta ttaaatgttt agcttttctt taatattttt tatataacga cgatttataa
     3601 taactttttc gttgtttttt aaagtagctt gcatgcgatt atgtgatatt acttttatac
     3661 tttttatgta gtccatattt aaaatcatgg atttagatat tcgtgagaag gatgtattag
     3721 ctaataattt tgataattta tatattttta aatcaatttc aaatacatca tcttcataat
     3781 aagcaaatgt tttatttcca actgtctcaa agtataaaat atcacagaca ttgagtttat
     3841 aaatctctcc tgatttttta ccttttatat caagtaacgg tgtactcaat aatgaaatta
     3901 ttttttcaat gttattatct agagcagaac attttatggt tatttcaata tcatcacaat
     3961 taataccttg ttcgacatgt attttcatta atcatcacct cattttatta ctgtcattag
     4021 aatagcatta tatcttattg agtccaacta gatgcgttct aaatttcaaa ttaagcatag
     4081 tgaaattcaa aaataaaaca gtgaaattca aatttgaggt ggtaaaattc aaaaaaatac
     4141 tatggatatt tggataaatt atccaaatat cctagtattt cacatagaat atgtctaatt
     4201 attttacaaa tagacctatt ttatgactta catatattgt caaattactt cttaaatatc
     4261 aaaatatttt tggataatgt atcaatactg tttgataaag tatttaattt accctcaatt
     4321 ctaaccaata agtacatgga tagagctata ggaaaaccaa cattggttat taacagttgt
     4381 aaactatcat ccataaaatt agccccctat tctataacta agtcataagg agtggtattt
     4441 gttttcacaa ccttggcttc aacaacagaa gctaggtcaa atcctccaac cgaaaaaata
     4501 tttttagata ctatcaaatc catgacagat tttatatttt cttcagttaa atcatccttt
     4561 ggattttcta tagaaaaaga aacttgttta tcctttacat ttttaaagct catgactaat
     4621 tttttcttaa tttccatata attacctccg atataataat ttatatttta attgtttgct
     4681 tattaatatt ggtattttaa ttgtcaatat tagtgttttg cttgttagta ttagtatttc
     4741 aattgtcaat attagtgttt tgcttgttag tatcagtgtt tcaattgtca atattagtat
     4801 tttaattgtt gactctagtt attgctgata tagaaaatat ttaatttatt tcaattaatt
     4861 agattaaagt agggtagcat ctaaaatagc taacatgttt aagttgaaat cacaaagtaa
     4921 tttttgacta tcttttcaaa agttcttata tgccggtata gcctattgtt acaggctttt
     4981 ccggcatttt tcgtcatgga agatattctc aaatcttctt atatccccgt atgttttggt
     5041 gttcaaaagt agtatgtgga gtagtaaatt ctccatttac tactatgcaa tcagccgctt
     5101 catttctgtt attgacgttt cggaagttgt gtgtgcgtaa tagttcagcg tcatattgat
     5161 gttggaatgt cccatgatgt actgcaatgc tttggggttc attcccgcat ttgctaacgt
     5221 ggtgcagaat gtgtggcgta aggtgtgcgg tgtcattacc tttggcaatg ctaccttttg
     5281 cgttttgttg tatttcctta caagcccccg gaacatactt tcatagttga ctgccacttt
     5341 tggcaaaccg ttccggttaa ggaacagaaa ctttgtgtag ccctctaaaa taacaggctg
     5401 tgtatatttc cgtttgttca gcacccgctg aaatgcttcc aacacttttt cactcatagg
     5461 aataatccgg ttgccgcttt tagtcttagg cgtttctaca tagtagccca cgtctgcaat
     5521 cttcaaaagt tggtggtcta cattgataag ctgtttatct aagtcaatgt cagcttccgt
     5581 caatccgcag agttccgaaa tgcgaagccc tgtccctaac agtatgataa tctcgtcgta
     5641 gtatttctga tagactttat catgctgcac aaaggacagg aaagccgctt cctgcgtagg
     5701 ggatagaggt tcctttggtt ccgtatcatc ttcaaggact gtgttcaact ggaagtcaaa
     5761 cggattttta cgaatacaat cgtcctgtat ggctgtgtaa aaggcagcct ttaaggaacg
     5821 cttgtggttg ttgatagtct tgaagccata acctttttct ttcatgcgta atgcccattc
     5881 ctttgcgtcg gagagcttta cattttcaat ccggcaggct ccaagtttat cctcctgcaa
     5941 aatccgcatg agctgttttc gcccctgctt tgtaccatgc ctcacatttg cccggtggcg
     6001 tatctgcttt gcgtaaagct ggcagactgt cattttcttt ccgatatggt cgataccgtc
     6061 gtcaaggtct ttttggattt ctttctcttt ttccctcaac gctatatcgt cgcgctttcc
     6121 tgccggggtt ttgtccgtag gtactaactt ccaagaatac acaaactgcg gttttccaaa
     6181 ggtatctata tatttgtagg catatcttcc gtcttttctc tggctctctc cggtgcggag
     6241 aatacgattt ttattatccc gtcttttttc cgacatcgtt atgctccttt ccataatgga
     6301 aagagccttg atatgcttga ctacattgta ccacattcaa ggctcgattt cactattaga
     6361 ttgcgtccac cgtatcaatc attttttcaa attgctttcg cttaatctga atacggtttc
     6421 cgttcatcat tacccagtcc gggacgggat tttcttctgc cagtttacgc agcttacttt
     6481 ctccgatacg gaaatatttt gcagcttctt ctatggtaag ggtgtatttt tcccaaatcg
     6541 gcacgtcgtt attgttcatt ttgtcgtccc cctttctcaa tgggtcaaaa gtcaatcagt
     6601 aacataggct ttaatcggac ggctgttagc gcaacctcat gggacttgca cccctccggc
     6661 ggtctgccga agccctaccc attgcctgcg acgcttctaa cgctcggact atggctgtaa
     6721 ggaagtatca ttatgtattt tgtgtgttat cgcccgcagt ctgctatatc tgctttgcgg
     6781 cgtggtggtt ctcgctcgct tttccagtag ggggaaaggt catggcgcac ccgccgtatg
     6841 gctcggcaca aaaggaacgt atccgatttg ccttatgctg cgtcgccgtt ttcttgcgcc
     6901 gctttctttg tcaaagagca gggggctgtc ttgcggtatg gaacggaaaa ggggaaagaa
     6961 gcgttccaat atcgcatagg ttattcagcc cgaaaagtga ggatagccct catcagtctt
     7021 gcttgcagtc gttcccgaat atcctcgtca acgccataat agacattgcc gcgctcgtcg
     7081 tagagcttcc gcatggaaag acttgctatg tagccgctga aatgctgcaa gaccattttc
     7141 atagcgtccg ggtcgccttt gctcgccgcc aaaataacgg gatagggaac aagggcattt
     7201 tccgggtagt cgttttgatt accattcgtt ccattcatca gcgtgttcct ccaaatattt
     7261 ctttaacagt tcaaaagagc ttgtccgtct gtactgtatc gtgctgcgcg atgtattgaa
     7321 catctttccg atttccacat cagtcatgcc ctcgaaatag tacagaagta tggcagttct
     7381 cttttcttcc ggcagggtgc gtattgcttc aagcaataac ttcggggtta tttcttttcc
     7441 tgccatttga taagtcggct cggctgtttc agcttgaaaa tacttatccg tagtgtaaag
     7501 ctgccgttcc tcatgcaagg caaggtcaca aaaagaaact tcccgtttcc tgcgtcgccg
     7561 gatttcatca tgggcgttgc aggcttcgtt gtgcagcacc cgtttacaga aactttgaaa
     7621 ggcacattgc ttctgaaatt ctctgcgatt aggttccatg taatcacctc ctttctgccg
     7681 aaaggcgggt agtacctccc cttttcgcgg gataatacag acgacttttt caaacgccgg
     7741 acgaactgga aaatttattt gaaaaatctt ctgtaaagtg caaaatgcgc ctgcccgcaa
     7801 aaaggcgcgg acaggcgcaa aggaatagta aacagtattt agatgtattg atagttcata
     7861 ttcatagcca gacttacccg gtgggggaac tgtacttttt ttaatgaatg taacctatgt
     7921 atgctgtata gcaacaaaga aatccccata gcggcagccc tcctaaatgc cgctaattta
     7981 tgttataggt tgtcgtgatt tagcagtaga caaaaaaagc ggcggctcta aaaatcaaag
     8041 ccaccgcttc aaaggcgcgt gaaagtgtat ctgctctgcg acagcttttt ttcttttgcc
     8101 gtcgttcggc aggtactatc aatcaaatta tttaccaacc cttttttcta actgcttttt
     8161 tcttcttacc aacagtcaat gtaccgggtt ctttcttttt atttgcaaga ataatcatag
     8221 aaatcaagaa agtcaaaact attgtaatga aagcggggaa aatgtgataa gtataaccat
     8281 attccgtacc acaagtaggg tctactaaaa tcatgcttgc tttaatggga taataattta
     8341 acagtgttcc ttcaaaagtt ccaaaatatc catacacaaa agctagtgca actccaccca
     8401 aaaaattatt tgccgaacaa cagaatatca gaataatcgg caagactgaa atataaattc
     8461 ctatattcgc cccagtaaca cgaataaaca tattgagtag attgccaaaa tgaactcccg
     8521 gaaatccgac aataatattg attactaatg ctatcacaca acctataaga ctaaagctga
     8581 ttgtcaacag caatagaata agtaattttc cagaaagtaa ctgtttatat ggaataggaa
     8641 ttgttaatat attcttcata gtatcgtctg tatattccct tgttatgata taacctgcaa
     8701 tcagcgcaat aataatcggg aaaaataagg tacagttact aatcataacc tgttgcataa
     8761 aatagtcaaa cgtccatgtc tgtccaccgt tggctgtgga ataaaacagt gacagcaacg
     8821 gagaaagtgt tgtcataata attccggctt ttattacaga atatcgtttt aattttaaaa
     8881 attcagtttt tattatattt ctcatatctt ttacctcgtc cattttttat aaaagcgaat
     8941 tatcagccac aaagaaagta taactgtaat tgccataata aaaattgtat ggcaagtggt
     9001 tggtacaatc gcataggctt ccggcaaaag attatctttt tgcaaattat ccatcattaa
     9061 gccgcttgtc cagttcataa cacatataac cggaaaataa tttaagaaag caattttggc
     9121 agcacttata gatgtcccaa tcgttcccag tatgccccag ttaaaaatgg aataaaaaaa
     9181 tgcaagcagg atagaaagta aaaaactttt gttaaagtaa ataattaaaa atacaatcgg
     9241 taaagaagct gctacgataa gaactccaaa aataaggctc ataaatatct tataagtcat
     9301 accgtaaacc attcctacat gaaacaattt acaaaacaac gcaacagata atgtgcttat
     9361 cagacaaaat gcaacgctga aaataaagag catagaaatt tttgccataa tgagttgtgt
     9421 atttgtaact ggaattgttc taaggttttt ggaagtatca caatctcttt ctataaaaaa
     9481 caaaatagcg gcaatgatac caattagaca tggaagcaaa aaaactaaac catatcccaa
     9541 catcattgta taaacataat caaatcgggt ttgaagatag tgttccgttg tatctgcacc
     9601 ggttcccgcc tttgccatat atgccaaaat caacggaaaa aataacgaca atgacatcag
     9661 tgcatacaac agtctttttc gctttaattt ccaaaattcg cacttaatca gtttaagcaa
     9721 ttccttcgcc tcctgtcaca cgcttgaagt aatcttcaag actttcttca caagtatg
//
LOCUS       DAEPUT010000122         9647 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.126, whole genome shotgun sequence.
ACCESSION   DAEPUT010000122 DAEPUT010000000
VERSION     DAEPUT010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9647
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.126"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(412..996)
                     /locus_tag="KRL22_003531"
     CDS             complement(412..996)
                     /locus_tag="KRL22_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH1273963.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
     gene            complement(1318..3162)
                     /locus_tag="KRL22_003532"
     CDS             complement(1318..3162)
                     /locus_tag="KRL22_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH1273964.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFENSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYHSEIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVSISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASNAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            complement(3457..4419)
                     /locus_tag="KRL22_003533"
     CDS             complement(3457..4419)
                     /locus_tag="KRL22_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBH1273965.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            4610..5161
                     /locus_tag="KRL22_003534"
     CDS             4610..5161
                     /locus_tag="KRL22_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1273966.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     repeat_region   6396..7747
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=6727..6755
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            8394..>9647
                     /locus_tag="KRL22_003535"
     CDS             8394..>9647
                     /locus_tag="KRL22_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1273967.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKESSMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTLDSIADTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLI"
BASE COUNT         3536 a         1414 c         1041 g         3656 t
ORIGIN      
        1 ctctttcata aaataaatgt tactcttatt aataaaaaaa attataacca cttttgatta
       61 ctaatcaaaa gaaaatatct aagtaaaata aaaattatat ttattaagct ttatgtatta
      121 tagtatttta ttcttactta atcatcatac tatagcaaaa tactaaccta aaagttagta
      181 ttttacttaa aaataagtgc ttattcaaac atcaaataga atatatacta ttataaataa
      241 atctataaag gaatgacttt tataaaaaaa tggtggaaat gcaagacaga agtgataaaa
      301 actacattcc acaaaaattt aacaaatgaa tatggatgtg aaagtattag aaaataccct
      361 atgtataaag taagaaaggt gttttttgag attttgcaag aaaatttaac tttatttatt
      421 ttctcgaata atacggcatg gatttccgta tgcaatcata ttacttggaa tatcttttgt
      481 aacaatactt cctgcaccta taactacatt atctccaata gtaacacctg gcatgataat
      541 agcacccccg ccaatccaaa cattatctcc aatagtaact ggagctgttt gagttttaca
      601 aaattcaaat gaaccatctt ctttggcatt accaaatcta tcaccagcat tagttggatg
      661 aaatgcagta tatatttgta cgtttggtgc gattagtgca ttatcaccaa tgataatttt
      721 attatcatct aaaaacgtac aattcatatt gacttcacaa ttatttccaa aataaatatt
      781 atttccataa tctacataat acggtgcagt aatccataag tttttaccct taccaccaag
      841 taattcattt aatatttttt cttttttttc caaatccgag gaatctgttt ggttataatc
      901 tcttactagg tcttttgctt tatgccattg agttaacaac tcaatatcac cacaatcgta
      961 aagttctcct gccaacattt tttctcgctc tgtcatgttt ttagtcctcc aaatttatat
     1021 tgtttttcat atatattcta gcataagatt tattaattta tatattttac ttatataaaa
     1081 tttaataaat aacaagattt attaaatata cagttgacaa tctatctctc tgtcatctta
     1141 aaactctttt aactgtaata atctcagagc aattttttca cttttattcc ttgtttatag
     1201 ctgataagca caatttttat aagaataacc ttaatttaac aaccttattt atgttaaaaa
     1261 gagatattat tgattttaat aatatctctt ttactggata atacaattat agaatattta
     1321 aaataaataa tctgacactt gactaataaa tccatttttc ttccaataaa ttgcactctc
     1381 tataaggtat ggattatctg taataatact atctacattt aggtcaagca ttttctcaat
     1441 taaactgtca ctattaacag tccaaacgaa gatttttttg ttcattttat gaatcttttc
     1501 tactactgtt ttattaacaa aagttgattc aattccatat atatcaacat aatttaactt
     1561 tgaaaaatca ccatatgcaa ttgccataaa atagcatgtc agtaaattct catccagttt
     1621 ttttactttt tgtaatatag ttttatccat agatgcaact atacattgat tttcaaaatt
     1681 attttcttta attaactgaa caactttttt tactacgtct cccttttcat gtccattaag
     1741 ttttatttct attaataatt tcaccttacc tttagaatat tttatcattt ctttgagtgt
     1801 tggtatcttt tccccaacaa acttttcatc ataataacct tttccataat aataaaagct
     1861 tcccgcatca tatgtcttta cttcattata atttacatcc caaacatttt tatctactcc
     1921 tgtagttctc ttaaagtttg aatcatgaag tacaataagt tctccatctt tagtttcttg
     1981 aacatctatt tctgcataat cagctttagc atttgaagct tcttctattg ctgccaaagt
     2041 attctctgga gccatttcag ctcctgctct atgagcaatt gctgttgtat aaaatgaaaa
     2101 tgacgtatta aacataccat ttatatgtga agaaaatgca actgactcta tataagaaat
     2161 caataatatt aatactaaat taaaaacaat ttttgatata gattttttct cttttttaat
     2221 attattttta gaaatactta ctcctttata ttgataataa gttgctgaga taaatccaat
     2281 gtccaatata aaaatgaata ttgataaaat caatctaaaa tattcttcaa atgcaataca
     2341 tctatttata aatacattct tcaaaaattc catatcagta caatatttag tccatatgcc
     2401 tataaatata atttcactat gataaatcgc atatccaata atagctacta ctaaagataa
     2461 tattaatgaa taaataattg ttcttataat ctttcccttt ataagattaa cactttcttt
     2521 tcttgctctt ttaaaatttt ctgtatttaa agttatctca tgaatgctaa aaatccatct
     2581 aataactgaa atatatatta ttaaaagaaa aatcatatag attatattta aaattatatc
     2641 agactttata taatctaata tgtactctgg tatttgtatt tttcctataa accctgaaat
     2701 taaaactgta tttactaatg gaattattaa tatcacaaat ataaataata gtatattttt
     2761 aggatataac aattttatag agttctcaaa tgatatttta aagagttcaa ataaccctat
     2821 tttttcatat tttatcgatt tattaaaaca aataattaca gaggtaaatt caaaaaatgc
     2881 ataaaaagct agtattataa ctgatagtat tatcagaact attgacatgg gattggtcaa
     2941 aacttttata aaattatcca tatttaggta gactatatgt aaacttttta ttaaaatatc
     3001 aaatatatat ctaatagatg gccatataaa aaataaggct aatcctttat gaaataattc
     3061 aaataaaatt aatgtactaa aattatattt tattataaaa acaagtttac ttaaaatatt
     3121 tttacccgta aatataaaat ttcttaaaat tctcttttgc atttttatct ccttgtatct
     3181 atttgttcta attttatcat atgttttaaa tacatttaga acattaatat gtattattcc
     3241 aagttatgat gtataaatgc aaaaacacat actctttttt attgcatagc taatcatcaa
     3301 tatctatata gcttaatact tataagtagg atactccata tttacaaaat aaaaaagtat
     3361 ctcctttata actttcaaaa attacattga gatacttttt ataatttaaa tctatatact
     3421 taatttaaaa aacattgcat aactattgtg ctattattac aattcttcat ataaatcagt
     3481 acttaaatat tttaaaccac tatcattaag agttaaaact atattttttc ctttttcact
     3541 gctctttaat aacttaattg ctgcacatac atttgcccct gaagaaaatc ctgcaaatac
     3601 accttctaat ttagctaatt ttcttgctac atcagttgcc tcctcgtctg taacttgaat
     3661 ataaccatca ataagtttct tgtctactaa tggcaaatcc atagaatatc ctccaccttg
     3721 tattttatgc ccttggtcag ttatttcttt acctgaataa attgctgctg tttcaggttc
     3781 aacaacataa catttgatag aagaattatg ttttttaagt gtttttgaac atcctgcaaa
     3841 agtactacca cttccaagaa aatctacaaa tacatcaata tttccatcca attgttccca
     3901 catttcttct gctgtatact tttcatgtgc atgattacaa gcttctaaat taaattggtc
     3961 tgctctaaat gcatttcttt cttttgctat tttttgagcc tcaatttcta caagtgccaa
     4021 atcttcacca gatacctgtc catgaactga attaggcatt tggtctacaa gaactacttc
     4081 agcacctaaa gctttcatca ttcttgctct ttccatagaa tttccttttg acatacacgc
     4141 tataaattta tatcctttac atgcacaagc tattgctagt cctgttccag tattaccact
     4201 tgttaattcc acaactgctt gacctggaac taataaacct gcattttctg cttcggtaat
     4261 catttgtaat gctacacggt cctttttact aaatcccgga tttaagtatt ccatctttgc
     4321 ataaatatta ccttgaactc caaattcatc tgctattttg gataaatgta acatatgagt
     4381 attgcctata gcctctgtaa cattattaag tacacgcatt acaattcccc cttaatctct
     4441 caactatcat ccgttgaaaa acaactcttt atgcagtata atttatatta cggatgtaca
     4501 gtgtatttaa cgttcattat attatacatt tgtaaattat aaataatgtt aaataaatta
     4561 tacattcgta aattatattt gtcaataatt tacattttaa ggagctacta tgagtattaa
     4621 tactgttatt gctaaaaatt taaatagatt acgtaatgaa cgtaacttaa gtctaggtca
     4681 acttgctgaa ttatctggcg taagtaaagt aatgctttcg caaattgaaa agggagactc
     4741 aaacccaaca gtaaacacaa tttggaaaat tgcaagtgga ctaaatgttc catatactgc
     4801 aatactggaa caacctcaaa atgaaacttt tattgtatca aaaactgata tagatgtaca
     4861 agtttcagaa aataaagatt atcgtcttta ttgttattat cccaatacac caactagaaa
     4921 cttcgaatta tttcaaatgg aattagaaga aggtcatagt tatacatctg ttggtcattc
     4981 tgaaaaatca caggaatata ttatgattat agaaggtcaa ttaaaattag aagtaaatga
     5041 ctctatttat caacttagag aaaatgactc tatttgtttt tcagctgaat caattcatac
     5101 ataccataat caaggagaaa aaacattgaa agcagtaata ataaattatt atccagttta
     5161 gccatgccat ttaataatag aataattatt ttctatacaa aaagataaat cctttgatta
     5221 ggatttatct tttttatttt atttttcttt ataaattcat tatatatctt tacactttta
     5281 tcaattatgt tataataagc ttatataaaa gttttatatt tttgacaaat ggagtacaaa
     5341 atactccttt ttctttttta ctattgtgat aattatttag ttagtattaa aatattatca
     5401 cttaaaacaa atacaaaacg tctcttatat gtacattttt cattgttgta ataatgattt
     5461 gtgtatgtat ttctcacaat tggagtgctt atgcactctt tttaaatacc tttattacca
     5521 taacctaaaa gctattttat tatccctttt agtttatttt taagtagtta aataaattat
     5581 tttatatttt tttcttcatt tatatgaaac ttttgtttta tcactatatg cactttatat
     5641 ttactacaaa taacacataa gcttactttt atcataagac tcctatatct aaatataatt
     5701 taagaggtta aataattgaa tagtatatta aaacataatg gtaatgacaa aaatataaaa
     5761 atctttatag tcataaattt tatcttatca tttttatcct ctccattaaa ataattatct
     5821 tgataaaatg tagctctatt ttgataacct gtttttaaaa ctccattttg aattaacagc
     5881 agtataaaaa agattgctaa taaaataaag ttataatttt tttcttttaa tctaaaatta
     5941 gctataataa caatgaaact atataaaaca tataaaaatt ttttcataaa aaacacctaa
     6001 attctatatt tgtattttat attgagccaa atctaatttc tgtatattta ttaagtgtag
     6061 ttctagttcc tattgtaata gcattaaata ttttttaatt tttattttca aagggcatct
     6121 ccttatattt aaattatagt atgaatattc ataaatttca atctatttat aaggtaatta
     6181 ttttttatat ctaatatctt gtcattaagt tttattatat atatgtataa atttttcaat
     6241 actttttata attattctac ttttatattt taatcattaa aactaaagtc aatgttatct
     6301 ggtaattatt tactacaaat gctaaaaaat aattatattt taaaggagaa aatgctgtat
     6361 aaattattgg ggtattttac ctatacttgt tgcaaattta cataccacgt agttaatata
     6421 aaacaaattt caaagatatt ggacaacgaa taaaaattgc aatttatata ccatatagtt
     6481 aatataaagc atatttgtgt cgatatatag ttctaactaa gtataagatt tacatacctc
     6541 atagttaata taaaacaatc tcttatactg aatacattag tttttaaagt gttatttaca
     6601 taccacatag ttaatataaa actttagatt tacctgctaa tactactgac gttattttct
     6661 aatttacata ccacatagtt aatataaaac actttatggt actacagaaa cttctcatat
     6721 tccagaattt acataccact tagttaatat aaaacgtttc gccaatggct ttggacttga
     6781 atgtattttt cgatttacat accacttagt taatataaaa cttatgctct gcaaatgttc
     6841 aacgtcttaa tacctcaatt tacataccac ttagttaata taaaactagc gttcataatg
     6901 ctttcagtgt tgtcagcaat ttgatttaca taccacttag ttaatataaa accccataat
     6961 ttgccattac tgatgtgttt aagtagctat ttacatacca cttagttaat ataaaactca
     7021 tagtatatat tactatcaat gttttttatg tttatattta cataccactt agttaatata
     7081 aaacttacag ggtaataaga taaacataac aaacaatgac tatttacata ccacttagtt
     7141 aatataaaac ctgagaaaat tctatattaa attcaaatcc agcaagattt acataccact
     7201 tagttaatat aaaaccatta gcaaaaaagg ctggtttatt tcctgcttat atatttacat
     7261 accacttagt taatataaaa cggttgataa tgcaattgat gctggtggaa gggtactaga
     7321 tttacatacc acttagttaa tataaaacgt gcgttataaa agtctaagtt ttgttcttca
     7381 aatgtattta cataccactt agttaatata aaactagcgg ttattttcgt aaattttttg
     7441 tttttgcttg tcgatttaca taccacttag ttaatataaa actcactgtt cctgaatctg
     7501 gagcaggttt ataagtttca tttacatacc acttagttaa tataaaacct tgacttggag
     7561 cttgccaaag atactttaag attagattta cataccactt agttaatata aaacatggca
     7621 ttaggagaaa taaaaagcta acagatgcat atatttacat accacttagt taatataaaa
     7681 ccctctttaa agcgtgttac tggacttgga catggggaat ttacatacca cttagttaat
     7741 ataaaacccc aaaataaact aagtattttc agtacttata cacatacaac tctctcaaat
     7801 ttgcagtgaa ccatgagtag tgcaattgat aacatttatc atacaccctc aatcccttac
     7861 attgcaactg ttaaacccta ctttatcaaa aatatcgctc actgcaaaat ttatatattt
     7921 ttattatatc ataaaattca aactataaaa ttaaaatgga ataatttatc aatttaagaa
     7981 cacctacata tttgtaaata cttactatat tatctattct aatagttctt cttctagcta
     8041 gaactaatat aaaaatcatc tctgaaagat taggacatac taatataaaa ataactataa
     8101 atagatattc tcatatttta aacgatatgg ataaaaaagc ttctgaaaat ataatcaaag
     8161 ttctctttaa ataacattcc attttatgta agtaggcatt atatttttct taaatgtcac
     8221 ttaaatgtca gttatatata ataatagtaa acaactgtat ttcactaata tttgctatta
     8281 tctaatagta tttatagttt agatttgata taatacatgt ggtaaaattt tgatttgtaa
     8341 aacaaaattt tacctacata tattaaaaca aatttaaaac taaggagacc tatatgttaa
     8401 aagtattaaa aggaaatata atttttacaa aaacttcaga aactttcaca gtatttgaaa
     8461 atagttatat tatactggaa aaaggtaaag taaagggaat atttaaagag atacctaagg
     8521 aatacaaaaa cctaaaagta gtagattaca ctgataagct tataatacct ggtatgaatg
     8581 acctccatgc ccatgcctct caatttaaaa atcttggaat ggctatggat aaagagcttt
     8641 tgccatggct tgaaacttat acatttccag aagaatcaaa ttataaagat atagaatatg
     8701 caacaaaaat gtataaaaaa tttgtaaaag aactttggaa atctggaact acaagaatag
     8761 cagtgtttgc aacagtacat aaagaatcct ctatgaaact tatggatata ttcaaagaag
     8821 ttggtcttgg agcatacgtt ggtaaagtaa atatgaatat gaattgccct gatactttat
     8881 tagaaaacac tctggattct attgctgata cagaagaaat tataaataag tatagtgata
     8941 cagattctat tgtaaaacca ataataacac ctagatttat accaagctgt acaagtgaac
     9001 ttttaaaagg tttaggagat ttatgtttaa aatataatat tcctattcaa tcacacttat
     9061 ctgaaaatta tgatgagatt gaatgggtta gaagtctaga acctgaatct aaattctatg
     9121 gagatgcata taatagatat aatttatttg gtcaaactcc tactttaatg gctcattgtg
     9181 ttcattgttc tcaggatgaa atagatttaa tgagagaaaa taatgttatg gcagttcact
     9241 gtccagcttc taactttaat gttggtagtg gtgctatgcc tatcagaaaa ttaatcgata
     9301 ataatattag attagcactt ggatcagata taagcggtgg acatacattg tcaatattta
     9361 aagcaatggt atctgcaata caattatcta aattatattg ggttaattct ggtaagaagt
     9421 ataatttctt atctttatct gaggcttttt atattgcaac caaaagtggt ggaagtttct
     9481 ttggaaaagt tggtagcttt gaagaaggtt atgattttga tgcattgatt attgatgatt
     9541 caaatttaaa tcatgacaat tattctatac ttgaaagact tgaaagattt atctatgttg
     9601 gtgatgatag aaatatcatt catagatatg tatgtggaaa actaatt
//
LOCUS       DAEPUT010000123         9604 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.127, whole genome shotgun sequence.
ACCESSION   DAEPUT010000123 DAEPUT010000000
VERSION     DAEPUT010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9604
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.127"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            339..1274
                     /locus_tag="KRL22_003536"
     CDS             339..1274
                     /locus_tag="KRL22_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBH1273968.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(1366..3237)
                     /locus_tag="KRL22_003537"
     CDS             complement(1366..3237)
                     /locus_tag="KRL22_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBH1273969.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            3427..4353
                     /locus_tag="KRL22_003538"
     CDS             3427..4353
                     /locus_tag="KRL22_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH1273970.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            4492..4638
                     /locus_tag="KRL22_003539"
     CDS             4492..4638
                     /locus_tag="KRL22_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273971.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(4743..5267)
                     /locus_tag="KRL22_003540"
     CDS             complement(4743..5267)
                     /locus_tag="KRL22_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1273972.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAENNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(5320..5544)
                     /locus_tag="KRL22_003541"
     CDS             complement(5320..5544)
                     /locus_tag="KRL22_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273973.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            5741..6865
                     /locus_tag="KRL22_003542"
     CDS             5741..6865
                     /locus_tag="KRL22_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HBH1273974.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPSVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(7339..8163)
                     /locus_tag="KRL22_003543"
     CDS             complement(7339..8163)
                     /locus_tag="KRL22_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273975.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPVGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(8511..9566)
                     /gene="ispG"
                     /locus_tag="KRL22_003544"
                     /gene_synonym="gcpE"
     CDS             complement(8511..9566)
                     /gene="ispG"
                     /locus_tag="KRL22_003544"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBH1273976.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKRVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
BASE COUNT         3230 a         1569 c         1006 g         3799 t
ORIGIN      
        1 ttctttactc aaattaaata taacttatat actttatgtg taaattatgg taaaaatatt
       61 atttaatcaa atcaaaactt gatttatata cctggaaaag gtattatatt aaagagtgct
      121 taaaatacgc atttcataaa tagctatata aaataataaa taaggagagt gatgggcaat
      181 ggatactagt ccgttgcgga gagaattttt tacattttca tcacttaata atatctaaaa
      241 tcaaaactaa tacatatatt cagttatata aattagttaa ttaatagata ctattaaatg
      301 atgagattta tataaaactg aataaaggat gtgttgccat gataagatat tacaaaacta
      361 tagattcaaa attagagaaa cttagttttt ttgaagatgg ctgttggata aatcttgttg
      421 aacctaatca tagtgaaatc aacgaaattt ctaatttatt aaatatagat gtagaaagca
      481 tagaatctgc actagatgaa gaagaacgct caagaataga tgttgaagac aatcatactc
      541 ttatacttat agatatacca gtagacgaaa gtgactctaa ttcttctcat tatactacaa
      601 tacccttagg tattatacta actgaagaag ctattgtaac agtttgtgat gcacaaacta
      661 agattttaaa tgactttata gttggtcata ttaaagattt ttttacgttt aaaaagactc
      721 gctttttgct tcaaattctt cacaaaaatg cagcttatta cttgcattat ttaagaaaaa
      781 taaataaaat gacaatcata atagagcgag aaatttacaa atcaatgaaa aacaaagaat
      841 tggttcaatt attggaatta gaaaaatctt tggtatactt ctctacctca ctaaaatcta
      901 atgaacttgt tttaaacaaa atggttagaa ctgctggtat aaagaagtat ccagatgatg
      961 aagacctatt agaagatgtt atagttgaaa atagacaggc tcttgatatg gctaaaatat
     1021 atggagatat attgagtaga attatggatg ctttcagtgc aattataagt aataatcaga
     1081 ataatgttat gcaaatttta acagtagtta cactaatttt ctcaatacct acaataatat
     1141 caggattctt tggtatgaat gtcatcaaca tgccattttc taataaccca aacggatttt
     1201 ggataatact tcttattacc tctataatat gtatagtgat tacatttttc atgtcaagaa
     1261 ataagctatt ataaaatatt aataaaaaag ccattagaat taattgattt acatttatcc
     1321 taatggcttt tatatattta aatctatata atcctataat actttttaac tatcatgttc
     1381 ttcatctata atcatttcag tttcaagccc ttctagcatt gaatctaaac tttcttttat
     1441 atttagtata taaattggta catactcttc ttcatctatt acctcttctt gcaacttaaa
     1501 tggaggaatt aatacttcat caaagtctat atttaaattt ggaaagcctt ctactatctc
     1561 ttcacaatta tcgtactctt catttgctaa agaaatgtac atatctaggc tctttttata
     1621 ataaagacct gcaagcatat actcacactt cttacttcca tatttaatac cttctttata
     1681 atatttctca gcttctgcgt catcatttaa ttttaaataa atttgaccta aattatatat
     1741 tgattcaaca caaccttgtg ctctagcctt ttcataccaa aatttagaat ttacataatc
     1801 tttatagaac atatcataaa ttaatcctac catatgttga gcatacacat tattttcatt
     1861 ggcaggtgta tcaaacatca ttttagactc ttccaattta ccttctctaa aataaattct
     1921 acctagatgt atacgagcat tcatatggtt tttgctactt gccatttcaa aatactttct
     1981 agcatttttt gtatttccta agctctcata tatacacccc aatctataac tagacctcgt
     2041 atctccattt tcagatgctt tcttatacca acttattgct tcttcaatat tatttaaatc
     2101 ttcatagata tttcctaatt tgatttgaca agatacatta tttggaatcc tcgaataata
     2161 cgaaatcgct ttttctatat cttgattctg ataatataaa tcccctagat tttcaaggga
     2221 acttttgcat ccaacagcta tagcatcctc ataatattta atagcatttt cataatcttt
     2281 ttcttcaaaa tatatacctg ccagattatt ttttgcttct gttatatcat cttcagcagc
     2341 cattttataa taagtttttg ccttctctat ctcattttct ctattatata aattagcaag
     2401 tctatactta gaaagtgtat gatttttttc tatggctttc tcataataat aaattgcatc
     2461 tcccagctct tcttttctat catatacata tgcaagccta tactcagact tcacatcatc
     2521 tctatcagca ctctttttat aatacttctc tgcatcttct aaattatcat ttatttccat
     2581 aatcataccc aagttaaagc aacctttcat atgacctgac ttgtacaact gtttatataa
     2641 acttactgtt gatttattat ctttcttttt tccatttaat attgctaaat tatattttgc
     2701 atcatcatct aaaagcacag aacctttttt atagtattca tacgcttcat catctttctc
     2761 caaaaaagta tataataccc ctaaattaaa acaagcttta cctaaattct tgtctgctgc
     2821 tgtttttaac catttttcac accttacaaa atctttcatt ttaaaatggc atacacctaa
     2881 attattttgt gcttgtaaat aacctaaatt tgctatcttt tcataccaat atatagcata
     2941 ttcatagcca tctaacttat agtacatatt acctaaatca aaagcagcat cttcacttcc
     3001 acttttatat gccattgaat accacttttc tgcttcttta aattgttttt tactttcata
     3061 tatatttcct aaagtatatt gagattttac gtaattatcc aatgcagcac tcttatacaa
     3121 ctctattgcg ctttccatct tacccatctt ttcaaggagg gcacccttag tatgtacgac
     3181 tttcgggtca ttagatatat tttttatttt ttttatagaa aattttgtat ttttcattat
     3241 tcgctaccta cccattttat aaaatatatt ctctcaaaca ttattataca ttataatcta
     3301 caattaatgc tataatattg aatttttacc ttttgtcact atattgtaac attaaatttt
     3361 aaattttata atcattagat tttattatgt aattggtata taatgtatat atagggggga
     3421 cattttatga atttcagcaa tatttttatc caagttgcag ttttatttat aattatttta
     3481 gttggatatt ttgtcagaaa attcaactta ttagatgacc actgcacatc taagctttca
     3541 actttgacaa tgacagtttt tttaccatca atgataatta gctccatgca aattaacttt
     3601 gatagtaaaa tgatacaaaa aatactattg ttattattta catctttgat tatgtatata
     3661 gtttcaatta taattgcatt tttattgaaa tacattttaa aatgtaatga taaaaaagat
     3721 ttgggaatat atcagtatat agttgttttt tcaaatgttg cttttatggg ttatcctgta
     3781 attgaagcag ttttaggtca tgaagcaata ttctatactg caatattcaa tttgcctttt
     3841 aacttatttt ctttcacttt aggaatttat cttttatcta aaggcagtac aagtagaggt
     3901 ttttcaataa aatcacttat aagccctgct acaatagcta ttgttattgg acttttttta
     3961 tttgtaacag gacttaggtt accccaattt ataaacgagc cacttgagat gttgggaagt
     4021 ataactacac caatatccat gattatcatt ggaagcttac ttgctaattc ttcagctctc
     4081 gattgttttg tcaacaaaaa attatatata gtcactttta taagattatt ggtacttcct
     4141 gtgattgtgt attttattct aaaaggatgg ataaatgata agatgatttt agctatacca
     4201 gtagtaattt cttcaatgcc tgctgctgca aatactgcta taatggctaa tcaatatgac
     4261 tccaatataa cactagcttc acaatgtgtg ttttttacaa cactattttc agttatatct
     4321 atacctttta taagtatttt actcttatct tgatttattt ttttatgtat tatataataa
     4381 catattcaat aaattacaaa tataaacatt ttattgtagt atattgatgg aattttttcc
     4441 tagatatttg tcaataatat ctatatgtat tatagaatag gaggcttaaa tatggatatg
     4501 gatttactct ttaaaatagt atttgctata gttgctatag gtgtttctgt aaaaatcatt
     4561 aaaactgttg ctagtttagc ttttaaaata gcgttgatat tgctaataat tttatttgta
     4621 tatagaatgt ttttgtaaac atttaaaaat aagtttttta acacaataga gaagtaaaat
     4681 agattatctt taatgtaaat tttttattaa agacactcta ttttacttct ctattagctt
     4741 ctttaaatta aatttttatt atatcttccc ataatataaa catcttcaaa ttttccatct
     4801 ctgattacag catatttttt agttccctct atttcaaaac ctagcttttt atataaattt
     4861 aatccctttt cattatccac aattacttct aatcctactc tagttaacat aatccaatta
     4921 tctgctatat ctaaaagttg ttccataagc ttcttaccta ctcctcttcc ctgataattc
     4981 tctgcaacac ttattcctat ttctgcgcta tgtctcaatc gtggagaaga atttacatgt
     5041 aacccagcaa aacctattac atctttttct ccattattat tattttcagc tacaaacata
     5101 taatcatttt ctcccaaaga agctaacata gcttcagttt tatcgactct gtcactcatt
     5161 aatgccaaag tatttctcat aacactgtat gttcttctaa tttcattaaa agcttgtgca
     5221 tcttctcttc ttataggtct tattgttata tctataggct tactcatatt ggattccccc
     5281 tcaaacataa tctttatttt taattaaaat tttacatctt tattttatac tgttcaaatc
     5341 tatgtatgct tctacctgag gtacatatat catattatct tttatatgtg tacttccaaa
     5401 ttcttttaat tctgtacctt ctttatcctt agttatttta tatctaatgg attccatacc
     5461 ttcaactact tcagcatgaa aaaacatacc ttcatattgt ttaaatctaa aattaaaatt
     5521 gtctttagta agttttatta tcatattttt atctactcct tatataattg atatttttct
     5581 tattattagt tgtatatata ctgcttattc atattaatat attataactt atcatttatt
     5641 tagtataaag ttataaatag atatatttat acttatttta caatctttct tcaattgata
     5701 tataatatgt ttatataaac taatgtatgt gaggtgaaat atgagcaaaa aaacaaaata
     5761 tttttcttta attctctttc ctattgcttt gcttttaaat tttatagcca gcaaagttcc
     5821 aaatattgtt gaaaaatatt actcccaatt catagataaa ataattgtac aaatattgag
     5881 taaagtttct ggaattttcc cattttctct ctatgagatt acaatgtaca taatagttat
     5941 atctatcttc ttatttttat gttgtacttt atctacaatt tttaataaga aaaaaaaatt
     6001 aaacatatat ttaaaaaatt ccattttaaa tatattatcc attgtatcaa tagtctactt
     6061 tctttttgta gtgctttggg gaataaacta taataggatt ccactagaaa ccacacttat
     6121 aaataactat aatttaaaaa acaatacctc tatccaatca aaacaatata gtgttaaaga
     6181 gcttactaaa ttatataaat tccttgtaat taaagcaaat gaaactagaa aactcacatt
     6241 acaagataaa aatggtattg taaaatctaa tacagattat aatggtgtca taaatagagc
     6301 tcaactagga tacgataata tcttggatat attacctagt gttagtggta gttattctaa
     6361 gcctaagtat attatttcat caaatctaat gtgctataca ggaataactg gtatatactt
     6421 tccttttaca ggtgaggcaa atgtaaatat agcaatacct gacttatata ttccttgtac
     6481 agttgaacat gaaatggcac atcaaagggg atttgctagt gaagatgagg ctaattttat
     6541 agcgtatctt acttctataa aacaccccaa tattgatttt aactattctg gatatatttt
     6601 agctttaaat tatactgctt ctgctttaag taaggttgat tataatgcat atgttgatat
     6661 ttctgctggc atttcagatt ctgtccgtag agatttaaaa aatgaaagtg aattttggca
     6721 aaaatatgaa ggtaaaatta atgaaatttc taatgagttt aacaattctt acttaaaagc
     6781 taatggcgtt actgaaggta ctcagagtta tggtaaaatg gttgatttat tgctaactta
     6841 ttatgaatta tatccatata actaaacact acaattcaaa attttattca tatacagctg
     6901 atattaaatc agctgttttc tatttaaata aattatttaa cttcaaacaa tcttatataa
     6961 tttgatagta cttatactag ctgtataaca tttcaattct aactatttta gttaaaacat
     7021 ttctattatc ttttttaata aatgttttaa ctaaaatttt taaaacataa aacttccaca
     7081 ttatttcact atctatataa aaatctaaaa attcacatat aaaattacat aactaaaaaa
     7141 tcataaattt atagaaaaca tatattcaaa ataaaaaagc atgtatcaaa acttgacaca
     7201 tgcttataat cttatgtata tatatcattt tgtcacaata aaaatttcct tgtaacactg
     7261 atatttttaa acaaaatagt ccttatttaa ttaaattaac attaattaaa ttcgtactca
     7321 ttttgctatc attaaacatt acttatagta attttctaat acactatttg aaacttcctt
     7381 cccttgaaaa cttttcaacc aattctcata tgctgagttt ttccatacac taccatcatt
     7441 aaatgttact tgttttacac aagatataat gtactttaca ccatgctctc cagttgattg
     7501 tttccattta tcaaacaata gaaaggcatc attttgattc ttacctggtg ctattgcatt
     7561 ttgctttgca tattctttct ccatttgttt ccattctttc aaccaatttt ctacccatgc
     7621 cttgccttgt tgtttttcaa acatacttat tatatcctgt ggtggtgatt gttgcatttt
     7681 tctataagta tgtgaatatg attttggaga cacaggagat atgcctgtaa caataccata
     7741 gtctacacca actgggctaa atccaacact tcctacttcg ccatctgctg ccacattttg
     7801 agcatcccaa tatagctcaa gtggttttcc atttttatca tatgctaagc atgtaatttc
     7861 ataatccata attgcctttt cactgctatt tgttaagctt ataacattgc taggccaatg
     7921 atatggagta tcatcatact gtattttgct attatttata aataatggaa tattctcatt
     7981 ataaacaaga cctttactac tttgaatatc tgatactttc tttgtgacag tacttaccgt
     8041 atttgctaag tatacatttg ttttttctga attggtcgta ctaagagaaa atgttgttgt
     8101 cgttccagta atcagcaaag caacaactaa aataggtaag ctagatattt ttttatatct
     8161 cacagttctt cacctctttt tctattaact tataataaaa caatttacca aaacattaaa
     8221 atctatgtta acataattta ccaactgttc tagtaactat atcctatcat agttactatc
     8281 aagtttcaat actattgatg gaaattttca ctatattaaa tcttttttta attttataaa
     8341 tttacaatat gatttaactc atacatatat agtcaaatta gaatataagt ttcttacatt
     8401 taatgaagtt tataaaataa aaaatgacta gataattaaa tactgtaaat aaaaacttat
     8461 tacaaaagta tttaaaaatc tagtcattta atatatatat gaattgtata ctataatttt
     8521 tcaatctctt ctagcaactc atcaactaat ttgttaccat caatcattct aactatttca
     8581 ccctttttaa ataaaagacc ttcaccttta cccccagcaa tacctatatc tgcctctctg
     8641 gcttcaccag gtccatttac agcacagccc ataattgcaa cagtgatatt tttttccata
     8701 ctaccaatct tttcttcaac ctcatttaca acactaatta agtctatatt acatctacca
     8761 catgtagggc atgatataac tttaatctta tcatttaaaa gtcccaaact tcttaaaatc
     8821 tgtttaccaa caataacctc ttcaacaggg tcgcctgtta aagatattct aacagtatct
     8881 ccaattcctt taagaagaag tgctcctacc cctatagaag actttattgt tcctttgtga
     8941 acacttccag attctgtaat tccaatatga agaggataat caactctttt tgatattaat
     9001 tcatatgcat caacagtttt ataaatatct gatgatttta gagatataac tatattatga
     9061 aaatctaagt cttcaagaat cttaatatgt cccattgcac tttcaactaa tgcttcagca
     9121 gttgcagagc catacttttt taaaagttct ttctctaaag aacctccatt aactccaatt
     9181 ctaattttta aatttctttc cttgcatttc tcaactacca tcttaactct ctctatactt
     9241 ccaatattac caggatttat tcttattcca tccacacctt gttctatagc ttcaagggct
     9301 agcttataat cgaaatgtat atctgcaata attggtatat ttacactaga ctttatcttt
     9361 gctatatttt tagcagcttt aatatcagga acagcaactc taactatatc acaaccagct
     9421 tcctctaatc tctttatttg agctattgta gcatctgcat ctcttgtatc agtatttgtc
     9481 atagattgta tacttatagg attttctcct cctattttta cagttcctac acttacttct
     9541 ctcgtctttc ttctctcgta actcatattc cacctctata tattatttta tattgaatct
     9601 cttt
//
LOCUS       DAEPUT010000124         9485 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.128, whole genome shotgun sequence.
ACCESSION   DAEPUT010000124 DAEPUT010000000
VERSION     DAEPUT010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9485
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.128"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(440..574)
                     /locus_tag="KRL22_003545"
     CDS             complement(440..574)
                     /locus_tag="KRL22_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH1273977.1"
                     /translation="MWELLKDLLLVSFGIGIGVVLMCILTVGKEADRCMEEIKEREDN
                     "
     gene            complement(581..1780)
                     /locus_tag="KRL22_003546"
     CDS             complement(581..1780)
                     /locus_tag="KRL22_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1273978.1"
                     /translation="MNETDFLTALKEKRCAYGVSQTRLAIMANISREHLSRIEAGKVT
                     LTEDMKHTLLEAVEKFNPDNPMFLLFDYVRIRFPTMDIKHIIKDILKLNIDYMLHEDY
                     GHYKYTEHYHIGDVFVYVSQDEEKGVLLELKGKGCRQFESYLVAQERSWYDFFTDALV
                     EGGVMKRLDLAINDRTGLLDIPELIQKCEHEECISKFRSFKSYGSGELVKHNETDKYD
                     MGHTLYIGSFSSEVYFCCYEKNYEQYAKLGIPIEEVPIKNRFEIRLKNERAYYAVVEL
                     LTHYDAELTAFSIINQYIRFADKEPDKRKSDWKTNVRWAWFIGEGRPPVKLTTKPEPY
                     TLERTLNWLQRQVAPTLKMLKQIDKDNQTEYLETIEKQAKLTERHHQIIKQQTATVEE
                     MVANVKE"
     gene            complement(1982..3376)
                     /locus_tag="KRL22_003547"
     CDS             complement(1982..3376)
                     /locus_tag="KRL22_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1273979.1"
                     /translation="MKMILNKGHRIRASDKNLVYHFSIGTLLFVFIAVILLLNMKQLM
                     RTDWEHFSLLDNGLTLSTYNFITLLIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIIWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTMLYDMIANRITIDEVKAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAYARQ
                     DGTATCEAKGDGTD"
     gene            complement(3493..3978)
                     /locus_tag="KRL22_003548"
     CDS             complement(3493..3978)
                     /locus_tag="KRL22_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273980.1"
                     /translation="MAKEKGSFKEFLSAIAPEHQAFVEKLNTKLIEQGCDLVIKEAKS
                     GYTASYQLEKKTVMNWVFRKTGVFARIYGDNAGKYEDIIASLPADMQKKMTTSRDCKR
                     LIDPNACSDTCVKGFVYALNGDTHKKCRNDGMLFVLTNETAEHIAGLVCAEVNVRKSA
                     L"
     gene            complement(4076..4459)
                     /locus_tag="KRL22_003549"
     CDS             complement(4076..4459)
                     /locus_tag="KRL22_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1273981.1"
                     /translation="MRLANGIVLDKEKTFGVLKFSALRHEVRAENDDGSTSEEITRRT
                     YDLKCSVQERMIQVSIPADIPVKDYPYNAEVELVNPVADTVANASYRGVNVDWYIKAD
                     DIILKNKGGQAGNPQNHIPQGQPKK"
     gene            complement(4474..4800)
                     /locus_tag="KRL22_003550"
     CDS             complement(4474..4800)
                     /locus_tag="KRL22_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1273982.1"
                     /translation="MELKYVVPNMAQTFGNLEFAGENKIEQQRINGRFTPVSRSYNLY
                     SDVQRADDIIVTIPAKAGEKHFKPEQRVKLINPKITADGKAVKGRGFTNYILTADDML
                     PAEESK"
     gene            complement(5036..8080)
                     /locus_tag="KRL22_003551"
     CDS             complement(5036..8080)
                     /locus_tag="KRL22_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH1273983.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPTTLVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASSRMSADQISDVA
                     LSIEYVKQYTASHNEISNNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSNNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDNSGNTEVAEVKATTVYIKELTAPMGFKVDKT
                     IYSLKVEAGKTATLKVSDTPKVADTLIELFKIDMETQKANPQGNASLEGAEFTWKYYA
                     GFYTKDNLPAEATRTWVTKTIAETDSNGTTHYITKLADAYKVSGDSFYMQDGKAVLPL
                     GTLTCEETKSPTGYLLDGAYMKANGSEEQIKGLYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNDNSVLVEGKLYKKNEVVKTIH
                     TDIEGIASTSADLLPYGNFRIVEKQAPNGYLTDGAKPIDFAITENGKIVDLTDEAHSV
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSSDWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEITIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAEIIIDGKRVESDYTFVADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDEQTVLITERIIKIHTTATDKDSNKELEAGKDVTIIDTVT
                     LEGLEVGTKYKLVGWQMLKEENAELLINGKRVESDYTFIADSETMKVEVTFTFDATSL
                     DGKQLVTFEELYDLSNPNEPKKVTEHKDIEDEGQTITFKEKPEVPEKPETPTTPEKPS
                     RPTDSPKTGDNTNVMAFLVMLLTSAGGLAGTYLYKRRKMKKS"
     gene            8504..9181
                     /locus_tag="KRL22_003552"
     CDS             8504..9181
                     /locus_tag="KRL22_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273984.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
BASE COUNT         2547 a         2022 c         1741 g         3175 t
ORIGIN      
        1 tatatggcat ttcataacct atattcttac tttgccacac cagctacgat ttctcgtacc
       61 tttgcatttc taccaagtac aaatttagac ccgtacattc gctgtttcgt cagtcccttg
      121 tggaacattc taaccataga tattttatag acccccgacc tgttggatac gctacccacc
      181 tctggatagt tttcgataga agatatatgt tcatcaacta ttacggtatc tttcagccgt
      241 ctttaccgag cttcaaacat tctgagtttc ctcattcaat gcttgtcgga ggctcagggc
      301 aggcgtttca gagcgttact tcatcattcc acctgtcaga ttatcagttc tcctaataat
      361 caaacttttt cgttctttta ttagtgcctt agcttttcac taaggaacga gtcgcacata
      421 aattttgtcc gaaattcatt taattgtcct ctctttcttt gatttcttcc atacatctgt
      481 cagcttcttt gccgacagtt aaaatgcaca ttaagactac gccgatacct attccaaatg
      541 ataccagcaa taagtctttc aataattccc acatttttca tcactccttt acgttggcaa
      601 ccatttcttc aaccgtggct gtctgttgct tgattatctg gtggtgtcgc tcggtcagct
      661 ttgcctgctt ctcaatcgtt tccagatact ctgtctgatt gtccttgtct atctgtttca
      721 acatcttcaa ggttggtgca acctgccttt gtagccagtt gagtgtacgc tccaatgtgt
      781 aaggttctgg ttttgtcgtc agctttacgg gcggtcgccc ctcgccaatg aaccaagccc
      841 agcgtacatt ggttttccag tcgctttttc gcttgtctgg ttctttatca gcgaagcgga
      901 tatattgatt gataatagaa aatgctgtta gttctgcgtc ataatgtgtc agcagttcca
      961 caacagcata ataggcacgt tcatttttca aacgtatctc aaatctattt tttatgggga
     1021 cttcctcaat cggtatacca agtttggcgt actgttcgta attcttttca taacaacaga
     1081 agtacacttc acttgaaaat gaaccgatat acagcgtgtg tcccatatcg tatttatccg
     1141 tttcattatg ctttaccagt tccccagaac catagctttt gaaagaacgg aatttagaaa
     1201 tacattcctc atgttcacac ttttgtatca gctctggtat atccagcaat cccgttctgt
     1261 cattgattgc caaatcaaga cgcttcatca caccgccctc aaccaatgcg tccgtgaaga
     1321 agtcatacca gcttcgctct tgtgccacaa ggtagctttc aaactggcga cagcctttgc
     1381 ctttcagttc cagcaggaca cctttttcct cgtcctgcga tacatacaca aacacatctc
     1441 cgatatggta atgctcggtg tatttgtaat gtccgtaatc ttcgtgaagc atatagtcga
     1501 tattgagctt taatatatcc ttgatgatat gttttatatc cattgtggga aaacggatac
     1561 gcacataatc aaacagcagg aacatgggat tgtcgggatt gaatttttcc accgcttcta
     1621 aaagcgtatg tttcatgtcc tcggtcagcg ttacctttcc tgcttcgata cggctcaaat
     1681 gttcacggct gatatttgcc atgattgcaa gccttgtctg cgatacgccg tatgcacagc
     1741 gtttttcttt caaggcggtt aaaaaatcag tttcattcag ttgtcatacc cccaatcgtg
     1801 ataattttgt gatattgtga taatttcaag gctttatcac aaaaggcgaa atgtacgaaa
     1861 agcccttatt ttatgcgggc ttgcaaaggt ttttgtggaa gtttccgccg taattgtgcc
     1921 cctctgttag ataatgaggg gcttgtatct gctggcgtgg ctaacgccac accagcaacg
     1981 gctagtccgt gccgtcgcct ttcgcttcgc acgtcgccgt cccgtcctgc cttgcgtatg
     2041 caagtgagcc tatggtctgc aaaaaatcat gtccttttgg aactaagggt gtgtaaaatt
     2101 cactgatgac gcttgttccc acatcacaat agccacgtcc cttgatacgc ttctggaaaa
     2161 actgcttttt cacatcagaa ccgaacagca taccgtaacc taattcgctg atacgcccca
     2221 agccaacacg gaagttaaaa ttatctctga taccgtccga gaaatatttt gcgtctggac
     2281 gctggcaggc aacaataagg aaatatcctg cttgtcgtcc taacatgacg attttcttta
     2341 gctggctaag taggctcaca ctttcttttg tccccagcat ttcaaaaaac gccacatatt
     2401 catcaaagat aagaaagcag ggcggtaaac caagataggc atagttttcg cccgttttat
     2461 agtctgggtg tcgcttcatt tcttcgcttc tttgtaccat gccctcataa aaggcattga
     2521 cacaatcaat catttcttct ttggtgtgat acacatttcc catgaccgta cctaaatctg
     2581 caaggtcagc gttcttcggg tctaatatgt aaagaacagc gttcgtatgt aacagagctt
     2641 caataagcgt cagcagaaaa tacgttttac cgccaccagt cccaccagca atcagagcgt
     2701 gagggagtgc gtcatattcc catacaagat ttttcatcag cctaagacag ccgttttctg
     2761 ctttcacttc atcaatggta atgcggttcg ctatcatgtc ataaagcatg gtgtattcga
     2821 tataaccgtc atgtaacgtc ttgtcggtca gctcacaata caagccactt tccaatttat
     2881 cctctaaccg taagagctgg tcttgatatt ttcctaatgt aatttcacag cggatatgaa
     2941 gcagtccttt ttccatttga taataaatct ttggaaacca gatgattttt tcccttgatc
     3001 tgctttgcag gtcagtaaaa aaaccgctgt cttgtacggt gtctgcttca taccacttgt
     3061 tttccagtat cattcgtgcc agcttttgac ggtgcaggag cttcttgaaa ctgtcataac
     3121 agaagcggta atacagaaaa gcgaccaatg cacaaacacc agtcgctatc agtagggtta
     3181 tgaagttgta agtggaaagc gtcaaaccgt tgtctaataa gctgaaatgc tcccaatcgg
     3241 tacgcatgag ctgtttcata ttcagtagca ggataaccgc aatgaataca aacagaagcg
     3301 tccctatgga aaagtggtag acaaggttct tgtcgctggc tctgatacgg tgtcctttgt
     3361 ttaaaatcat tttcataaat caatcactcc tttctgggta cgaaaaaagc agtcaatcct
     3421 aagactaact gctttgtgtg tatggatatg aagttgtcaa actgggattt attgttctta
     3481 acttttctgt cgttataaag ctgacttacg cacattaacc tctgcacaga ccagcccagc
     3541 tatatgctcc gctgtttcat ttgtcagtac aaagagcatt ccgtcattac ggcatttttt
     3601 atgtgtgtcg ccattcaagg cataaacaaa acctttcaca caggtatcac tacaggcatt
     3661 agggtcaatc agtctcttgc agtcacgaga agtagtcatt ttcttttgca tatcagcagg
     3721 aagcgaagcg attatatcct catactttcc agcgttgtct ccgtaaatcc gtgcaaaaac
     3781 acctgtcttg cgaaacaccc aattcattac tgttttcttc tctagttggt atgaagcggt
     3841 gtaaccgctt tttgcttcct ttattacaag gtcacagccc tgctcaataa gtttggtatt
     3901 aagtttctcg acaaacgctt ggtgttctgg cgcgattgcc gatagaaatt ctttgaatga
     3961 acctttttct tttgccatta tctttttcct ccacaaattt caatttatcc gtttcttcat
     4021 acacatatta taacagttgc ttatatccgc tacaatgaaa atctagtttg ccagcttatt
     4081 tctttggttg tccctgtggt atatggttct gtggattgcc agcttgaccg cctttgttct
     4141 tcaagataat atcgtcagcc ttgatatacc agtccacatt gacacctcga tagctggcgt
     4201 ttgctaccgt atcggctacg ggattgacaa gttctacctc tgcattatat ggatagtctt
     4261 tgacgggaat atcagcaggg attgacactt gtatcatgcg ttcctgcaca ctacatttca
     4321 aatcgtaggt tcttcgtgtg atttcttcac ttgttgaacc gtcatcattt tctgctcgca
     4381 cctcatgtct aagggcagag aacttcaata caccgaaagt tttttccttg tctaatacaa
     4441 taccgtttgc taatctcata atcatttacc cccttacttg ctttcctcgg ctggcaacat
     4501 atcatcagcc gttaagatat agtttgtgaa ccctcgtcct ttgaccgctt taccgtctgc
     4561 ggtaatcttt ggattgataa gttttactcg ctgttctggt ttgaaatgct tttcgcctgc
     4621 tttcgctgga atggttacga taatatcatc agccctttgt acgtcagagt acaagttgta
     4681 gcttcttgat acgggcgtaa agcgtccgtt aatgcgttgc tgttcaatct tgttttcgcc
     4741 agcaaattcc aagtttccaa aagtctgtgc catgttcggc actacatatt ttaattccat
     4801 agtgttttac ctcgtttctt tcttcttttt taagtttgtt gattgtgctt tcttattctg
     4861 gcaattaggg aaataccagc aatcccccag atagtaaagg gtaaatcaat gcttcgcacc
     4921 cttgactatc cgtgtgcttg caggttgttg gcagacaagc cagaataagt aaacgtctgc
     4981 cgtttgacag cttcggcgta gagcgtgatt tttcttttct cataccgtta ccgccttatg
     5041 atttcttcat tttacggcgt ttgtaaagat atgttccagc cagtccacca gcagatgtaa
     5101 gcaacattac cagaaatgcc atgacatttg tgttgtcgcc cgttttagga ctgtctgttg
     5161 gtctgctcgg tttttctggt gttgttggcg tttcgggttt ctctgggact tctggttttt
     5221 ccttaaaagt aatcgtctgt ccctcgtcct caatgtcctt atgctcagta acttttttcg
     5281 gctcgtttgg attgcttaaa tcatacaatt cttcaaaagt tacaagctgt ttgccgtcaa
     5341 gagaagtagc gtcaaaggta aaggtaactt ccactttcat agtttcgctg tcagcgataa
     5401 acgtataatc actttccaca cgttttccat tgataagaag ctctgcattt tcttctttca
     5461 acatctgcca gcccacaagt ttatactttg taccaacttc caagccctcc aaggttacag
     5521 tatcaatgat tgttacgtct tttcctgctt caagctcttt gttactgtcc ttatcggtag
     5581 cagttgtatg tattttgatg atacgttctg taataagtac cgtctgttcg tcgtcctcaa
     5641 tatctttatg ctccgcaact ttcacgggtt cgtctggatt gcttaagtcg tataattcct
     5701 cgaatgttac cagattttta ccaccaagct cggacgcatt gaatgtataa gaaatttcca
     5761 ctttcatttc ttcatcatca gcaacaaagg tataatcgct ttctacacgt ttcccgtcaa
     5821 tgataatctc ggcgttttct tcctttaaca tctgccagcc ttttaactga tacttagtgc
     5881 cttttgtaag tccgtctaat ttgacagtat caacgattgt tacctctttt cctgcaagga
     5941 ttgtcttttc gccgtctttg ctggttgctg tggtatggat agtgatttcc ttttcgtatt
     6001 catcagtcaa agtccctaaa tcaatcacaa gattatttct tgataccacg atttcaaatg
     6061 gtggaataag ctcaaaacct ttgttgctgt cagagcgtaa ttcttcaata atgtaagtat
     6121 cgtaaggcaa cgcacctttg ctgtcgtctg gttcagaagt tccaaaccac acaccgtcct
     6181 cgctggtctt tcctgcgttg gtattgtgct tatgtgaagc ccagtcagaa gaagtggaga
     6241 attgcccgtt atcatcagtt accacaacat gactttcgcc cgttgtcttg cttgtgatcc
     6301 taaagggaac atcagcaaga cgcttgtgtg tgcctgcacc gattttcacg ccctcaatat
     6361 ctccacgttt aatctgattg tagacagagt gggcttcgtc tgttaagtcc acgatttttc
     6421 cgttttctgt gattgcaaaa tcaatcggct tcgcaccgtc tgtcaagtaa ccgtttggag
     6481 cttgtttctc aacgatacgg aaatttccgt aaggcaaaag gtcagcggaa gtagaagcga
     6541 taccctcaat gtccgtatgg attgttttta cgacttcatt tttcttgtat agcttgccct
     6601 caaccaaaac agaattatca tttaaggaaa tgatgtcaaa ggcagtatct ttcaaggttg
     6661 cacttccttg tggtttggta tcgcccgttt ctaaatctcg tttctgaatt ttgacaccgc
     6721 cacgaatgac tttgtctgat acagaaaact ggttacttcc agttaatacg gcaaggtcgc
     6781 cgtcctcggt aatctgtgta aggtataagc cttttatctg ttcttcacta ccgtttgcct
     6841 tcatatatgc accgtctaat aagtagcccg ttggtgattt tgtttcttcg caagttagtg
     6901 taccaagagg taaaaccgct tttccgtcct gcatatagaa actgtcgcca gataccttgt
     6961 atgcgtctgc taattttgtg atgtagtggg ttgtaccgtt gctgtctgtt tcagcgattg
     7021 tctttgtaac ccatgtacga gtagcttcgg caggaagatt gtctttagtg tagaagcctg
     7081 cataatattt ccatgtaaac tctgcaccct ctaaagaagc gttaccttgt gggttggctt
     7141 tctgtgtttc catgtcaatc ttgaaaagct caatcaaagt atcggcaact tttggcgtat
     7201 cagatacttt caaagtcgct gtctttccag cttcaacttt taaggaatat atggttttat
     7261 ccactttaaa tcccattggt gcagtcaatt ctttgatata tacggtagta gctttgactt
     7321 ctgcaacctc tgtatttccg ctgttgtcgg tcgtaagggt agcaagctgt tttgtgcagt
     7381 ccttatcaga aaagacaccg taagtcgcac cagcgataga gtaattcccg ttaccgtctg
     7441 taatgctggt attattggaa gttttttgaa gtttggcatt tccaacattt aacttcgccc
     7501 agaattgccc taattcctgc ccctcgccag aatagatata accgccacat tcatagcgtc
     7561 ctttgttttc tttgacaaag gcttttgcac cagcaaacac ttcatcttgc gtagcctttg
     7621 gaatttcatc ataagaagct cgcacgttat cacattgcca gcctaagtga acactcaatc
     7681 tttgccagac aacaagctgt cttaaaaggt aggcgtgatt gttgcttatc tcattgtggc
     7741 tggcggtgta ttgcttcaca tattcgatag ataaagcaac atcacttatc tggtcggcac
     7801 tcatacggga gcttgcgtca gctctggtct tatagccgtt cttaaaatct gtgttaatgt
     7861 caatacagta agcgtcctcg ccttcaacgg tcaaatgccc ctcgttaaag gtagaaccaa
     7921 tcgaaccgtc attcattacc ttttcaacga taccaacacg ttcttcactt tccgtccagt
     7981 attgcttact ttctgcatga acaagtgtag tcggtaaagc agtaacgaca gtcgcaaagg
     8041 caagtacgcc cgtacacaat cgtttcaata tctttttcat aattctaaat gctcctttca
     8101 ttttgggtaa taaaatagcc gttcaataag aacggctgga aatagaaaag gaacgtcatt
     8161 ttaggcgttc catagtctat gaaatattca atttttttgt tgcttcaata ctgatgtgcc
     8221 gtaccatatc tttgcatatc taggaaaact agcgtatcaa ggctcattca ttggtagtaa
     8281 attagtagta aattgatgtg tttgttttct tgaaaatgct gatagatact gtgttttagc
     8341 ggataatcaa ctttttagta tgttttttta ttaaaaaaaa ggttatttga aataaataac
     8401 ctttttttgt ctttttgtgt taacattgtc ttatagtgct aatgagtact attagaccat
     8461 gttctatggc cttattttaa tataaaacga ttggagatag gctatgattg tgattgaagg
     8521 tagcgataaa tttaagattg caaaagaata tattgatgta gaatatactc tttttagcaa
     8581 agtaactttt aggtatgaaa agttgaaatt taaagataat gctgaattgg aaaaaattaa
     8641 gatgtttaaa tataaaaatg gctacatccc taataaatta aacctttctt ttggatatgg
     8701 attctcttct tataaaaagc aaataattag agaaactgta gatactttaa gattgacaga
     8761 aattttttca agcgagaaca tagaagatat taaatttata aaagatggta caaaaaaatt
     8821 agaaattagc atagagaaag ttgtgaaatt taaacgtcga aaaaaaagaa attatgtttg
     8881 ttgctattgc cctgatatgt atagggacat aaaactcgac aaagaatcta tcaataagat
     8941 atacaacaga aaaataaaaa tagaaagaga agttaatatt tttgaagatg aggatgttat
     9001 aataaacaaa aaagtattga agtttccaaa gtcttggaca aagaatatgc aaaaatattg
     9061 gttaagtgaa aataagtatc ccatacattc tactgtaatt gatgatgata gatataaatg
     9121 ttgtaatgta caatatacaa aaaatagagt gataatatta tattacatat ataaccatta
     9181 atatacataa ttacaaaaaa ataatgacaa atatacataa tacaaatata tcttctactt
     9241 tagataaaac agttattatg aaaacttact atctataaat aatagaaatg ctagtatacc
     9301 atctataatc taatgtctag taggttttaa tggcatattt taaatatgcc atagttgatt
     9361 tataagattt tctatatcac tttcaaaata cacactaaat agttgctttt cagatataat
     9421 tgcccaattt aaattttact atctgaaaag ttttttatat ttaatttata tcttcaaaaa
     9481 taaaa
//
LOCUS       DAEPUT010000125         9268 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.129, whole genome shotgun sequence.
ACCESSION   DAEPUT010000125 DAEPUT010000000
VERSION     DAEPUT010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9268
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.129"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            391..1596
                     /locus_tag="KRL22_003553"
     CDS             391..1596
                     /locus_tag="KRL22_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH1273985.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1667..1888)
                     /locus_tag="KRL22_003554"
     CDS             complement(1667..1888)
                     /locus_tag="KRL22_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1273986.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2029..2628)
                     /gene="recR"
                     /locus_tag="KRL22_003555"
     CDS             complement(2029..2628)
                     /gene="recR"
                     /locus_tag="KRL22_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBH1273987.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKKEIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2641..2991)
                     /locus_tag="KRL22_003556"
     CDS             complement(2641..2991)
                     /locus_tag="KRL22_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBH1273988.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3050..4687)
                     /gene="dnaX"
                     /locus_tag="KRL22_003557"
     CDS             complement(3050..4687)
                     /gene="dnaX"
                     /locus_tag="KRL22_003557"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBH1273989.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4764..5028)
                     /gene="ffs"
                     /locus_tag="KRL22_003558"
     ncRNA           complement(4764..5028)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KRL22_003558"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5066..5157)
                     /locus_tag="KRL22_003559"
     tRNA            complement(5066..5157)
                     /locus_tag="KRL22_003559"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5121..5123),aa:Ser,seq:gga)
     gene            complement(5158..5613)
                     /locus_tag="KRL22_003560"
     CDS             complement(5158..5613)
                     /locus_tag="KRL22_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HBH1273990.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5934..7205)
                     /gene="serS"
                     /locus_tag="KRL22_003561"
     CDS             complement(5934..7205)
                     /gene="serS"
                     /locus_tag="KRL22_003561"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH1273991.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7331..7536)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7664..8545)
                     /locus_tag="KRL22_003562"
     CDS             complement(7664..8545)
                     /locus_tag="KRL22_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH1273992.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8557..9066)
                     /locus_tag="KRL22_003563"
     CDS             complement(8557..9066)
                     /locus_tag="KRL22_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBH1273993.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIKAIVK
                     ELKDNGILS"
BASE COUNT         2958 a         1627 c          989 g         3694 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata tcatctttat ctattctagt caatataatt
       61 ttttactttt tttaattttt ttatttatca tgtattcttt atctttaatt tttaaaactt
      121 aatgctaagt aaacctgttt atttcataaa actaatatat attctatgct ctattttcct
      181 ttttattcta tatttaaatt ttttatttac aagaatattt ttaatataac atatttgata
      241 aaattaattt acatttcttt cacttgtaat ttttgcaatc ttgtattaga ttaatattaa
      301 aaataattta tcaataacct tattcacaaa gacagttttt atatcaaaat ataatataaa
      361 tactatgcta cattttagga ggattttatt atgagcaaaa aagtattaat aatgtctgct
      421 tccactggtg gtgggcataa tagggctgct ctagctatta aagaagaact tacttccaaa
      481 acacttgatg gagagccaat tgaatgtgaa ataatagata gtttgaaatt agttaataat
      541 acaatggata aaataatttc aagaggatac gaaaaatctg ctatatatac tcccaaagcc
      601 tatggaagtg tatatagatt atctgaaaca aatcttttgt caaaaaatga atttaaagat
      661 aatctactaa taacattcat ggctaaaaaa tttaaaaagc ttattagaag cgaaaaacca
      721 gacttgatta taggaacgca tccttttcca atgattgctc taagtacatt gaaaaaaaac
      781 tttaatttac ataataatga atcaaatgct tacacagagc atttttataa acattataca
      841 aataccatta atgttcctcc gcttatttct gtattaaccg attatactac tcattctaca
      901 tggatacaaa atgaaattga ttactatatt gttggtcatg aatatgtaaa agaattattg
      961 gtgtttgatg gagttgaacc gagtaaaatt agaacatttg gaatccctgt tgaaaaatct
     1021 tttctctctc acagagataa agatattgtt ctttctgagt tgaatttatc tcctgataaa
     1081 ttaactgttt tacttatggg gggtagcttt ggggctggaa atataaaaga gacacttgat
     1141 gaattactgg atactgatag agactttcaa atacttgtaa ttactggtaa gaatgaaagc
     1201 ctaaaagaaa aaatcgaaaa aaaacttatg tctcgttatc atgataaaaa tgtatgtgtc
     1261 cttggataca ctgataagat gaatgatatt ttagcttcta tagatgtatt agtaagcaaa
     1321 cctggtggac ttactacaac tgaggctctt ttaaaagatg tacctatgat agttccttat
     1381 tatataccag gtcaggaaga agagaatctt gatttcttat ctaattgtgg tgcagcactt
     1441 agaactacaa aaaaatataa cttgtcaata ttactaaaag ttttaataga tgaccctagc
     1501 agattagaaa tgctaaaaag aaatattaaa tcaataagaa agtcaaattc agcccaaaat
     1561 atagctaatt taattttaaa tataatttct ggttgataaa ataaataaaa tccctatagt
     1621 atatatatta tctattaggg attttttatt ttctaattat ttaatattaa attggttcat
     1681 aaaagtcttc ttcataatca tactgataat ttttataatt atttctaaat tcagcatttt
     1741 tatttcgtac atttttttta gtttttttct tattagaaaa acttatatcc tcaaaatcat
     1801 catatttagg tttatctttt gatttcattt ttttaactct tttttctttc attgcattat
     1861 gttcttctaa gttcataatt ggtttcatgt tgcaccccta tcaaaatttt taaatgattt
     1921 atacaacaaa ttatacaata cagaagaaat ttattcaata aatctaaatc aaaattaatt
     1981 tgaatttaac tcaaaaaact acaaaaatcg aggtattaac ctcgattttt atatttctct
     2041 tctgccttct agtgcttttg atattgtgac ctcatctgca tactctaaat cgcctccaac
     2101 aggaagacca tgagctatcc gagtgacttt gattcccatt ggttttacta acctagcaat
     2161 atacatggct gtagcttcac cttcaatagt aggatttgtt gccattatta tttctttgac
     2221 ttcctgattg ccaagtcttt ggataagttc ctttattttt aacatatctg gtccaattcc
     2281 atccattgga gaaattactc catttaatac atgatactgt cctttaaact ctctcgttct
     2341 ctccatagct gctacatctc ttggatcttc cacaacacat ataacacttg aatctctact
     2401 tttatttgaa cacatgctac atgggtctgt atctgttata ttacaacaaa ttgagcaata
     2461 tcttatttct ttttttgcat ctataatcgc tttagataaa gcttccacat cattagtatt
     2521 catattaata atatgaaaag ccaatctttg agcagtcttt cttcctactc caggaagctt
     2581 tgaaaattcc tctataagtc tcgttatggg acctgtataa acttgcataa ataccaccta
     2641 ctagaataac ccaggtatat tcatacctcc agttacctta ctcatttgac ttgcttgtat
     2701 atcatcaata tttctcaatg cttgatttac tgcacttaaa actaaatctt gtagcatttc
     2761 tatatcatct ggatcaacta cttctggctt gatagttata tctataactt cttttttacc
     2821 attaactttt acagtaactg ctcctccacc aactgaagct tctacttctt tactttctaa
     2881 ctcttgttga gctttttgca tattttcttg cattttttga gcctgcttta acaagttgtt
     2941 catatttcca ccaccaggca tcattccgcc tccaaaacct tttttagcca taaacactat
     3001 tcctcctaaa cttattttca ttttattatt atatcataat agtattttat tatttactct
     3061 cattttcatc aatactatct tttatttcta atatctcttc actcactatg ttctttaata
     3121 tttcctcacc aatgtccttt ttctctttaa cttcaagatt tatatcttta acttctgatg
     3181 tcagtactat ttttacatta aaacttctat ttaaaacatc tcttattgtt ttttctaaat
     3241 aatttattgt atcttgagag ctcagtctag tttttgcaaa atcaaattta tcatcaaata
     3301 taacatacaa catattagaa tatacattaa aactttttac ttcacttaag agtgcgtata
     3361 ttggcatttt tttatctttt ttaatttgtt taagtatatt cttccaagat gactctataa
     3421 gtataacgtc ctcatttttt acatcttcat aaactacatt ttcttgtttt acatctattt
     3481 ctctatcgac ctcatactct ttttctttat tattcccaat tttttcagac ttaaagttcc
     3541 ccagttcaat cattttttct aagttctcaa ctctttttat aagagcttct ttactttcat
     3601 caaacattgg ttgagcaatt ttcattatgg ttatttccac taaaaccctt ggatttgaag
     3661 atgactttat atcatcctga gttattgata atatatttaa aatccttatt aaatcattta
     3721 tatctatatt tttagactga attttaagtt gttctatagt ttcttctggt aatgaaatta
     3781 tttcatccaa ttctgatgaa accttacata ccattaaatt tctaaaatga tcaattaagt
     3841 catttataag atttcttata tctttgcccc ataagacaaa ttcatttaat atctcaagag
     3901 actttttagt gtcctgctct acaatacatt gagacaattc aaataattgt tctatattta
     3961 cgcttcccat taattcaaca acatctttat aatctatctt actttctcca aaagacatac
     4021 attggtctaa tatactaagt gcatctctaa gagctccttg agaatttcta gctattaaat
     4081 taagagcttt atcatctata tcaattcctt catcttcaca aatctttttc attctaaggg
     4141 tcatatcttt aactgtaact cttttaaaat cgtatctttg gcatcttgat aaaatggttg
     4201 caggtatttt gtgaggctct gtagttgcta atataaaaat tacatatgat ggaggttcct
     4261 ctaaggtctt taataatgca ttaaaagctc cttgagacaa catatgaact tcatctatta
     4321 tatatacttt atatttagca ttggctggag aatatttcac actttctcta agctctctta
     4381 tatcatctac actattattt gaagctgcat ctatttctac aacatccatt gtattatctt
     4441 ttaatacaga ttcgcatatc tcacactcat tacacggttc ttcatttatt ttattcaaac
     4501 agtttactgc tcttgaaaaa atctttgcag tagatgtttt accagtacct cttgttccac
     4561 aaaacaaata agcatgtcct atattatcac tatatatttg attctttaaa gtcttaataa
     4621 tatgatcttg accaataaca tcttcaaatt tttgtggtct atatgctcta tataatgctt
     4681 tatgcatctt tttacctctc tttagcaaaa ttaataaaaa aatccctcat tatctaaggg
     4741 attagtcttt tatatattaa atgctgtaca ccatctatcg acttaattcc ataggcgtta
     4801 ccaaaacagt tagctcaact taggcacccc cacggcacac aaaagtgatc acttaccgct
     4861 gcttccttcc ggatctgacg gggttcatga gctttcattg cgcaggacct aagcatcaac
     4921 accacttatt tagggcggcc ctacagaaaa taagccttta gatggaattc aatcctgcta
     4981 tagcggattg caggttacag ggcaccgcta cctccccatc tagtacagca aaattacaac
     5041 catatttaat tacttttatt gtttctggcg gagagagtgg gatttgaacc cacgatacag
     5101 ttttacccat atactcgctt tccaggcgag cgccttcgac cactcgacca tctctcctta
     5161 atctcttttt ctcaatgcct taaaaaattc ttgcaatatg atcgagcatt cttcttgcaa
     5221 aacatcaaaa gctactttta cattattatt attaaaataa tctaatttaa actcatgctg
     5281 tttttctata tatgaatttt ttacatgtct tgtccctatt ataagctttt ttattctaga
     5341 attaactatt gcaccactac acattatgca aggttccatt gtaacatata aatcacaatc
     5401 agtcaacctc caaccaccta atttttctga tgcttgtttt atcgctaaaa tttctgcatg
     5461 tgccgtagag tcttttaacg tttctgtaag gttatgagct ctagctatta tttgattatc
     5521 tttaactata atagcaccta ttggtgtttc ttttttatta tatgctttat atgcttcttt
     5581 taatgcttct ttcatataaa atgaactttc cataattcct cccaaaactt ataacaaact
     5641 tatcttatca taattcattt tataattcaa cttaatttta ttttgtttat ttaattatta
     5701 ctatatatag ctatattttt tttaaattag ttctaaaata atttttagat attcatacaa
     5761 gagtgtttta taaaaatatt tagtgtttta tgatgaaaat tctgctgtgt aaattaacat
     5821 aaaaaaacta tgaaattaat atttataata atttcatagt ttttttattt attgtttact
     5881 cataatatat tctcttcatc aaagcatact ctacatatac aattaatata aatttatttt
     5941 ataacatcaa cacccatata aggtcttaat tcttctggaa ctactacaga accatctgcc
     6001 tgctgataat tttctaatat agcagccaaa catcttccta tcgctaatcc agaaccattt
     6061 aatgtatgaa catattctgc ttttgatttt ttatcccttt taaatcttat tcctgctctt
     6121 cttgcttgga aatcttcaaa atttgaacaa gaagatattt ctacatatct attgtagctt
     6181 ggcatccaaa cttctaaatc atatttaaat gcagctgtaa atcccaaatc tcctgtacat
     6241 atttttacaa ctctatatgg aagacctaac atttgtaaca tagtttcagc atcatgagtt
     6301 aatgattcta attcattata agaatcttct ggtttaacaa atttaactaa ttcaacttta
     6361 ttaaattgat gttgtctaac taaacctctt gtatctcttc ctgctgaacc tgcttcagat
     6421 ctaaaacaag gagtatatgc acagtattta attggaagct ctgcaacatc taatatttca
     6481 ttagcatgta tattagtaac aggaacttca gctgttggta ttaagaaata ctctaatcct
     6541 tctattttaa acatatcttc ttcaaattta ggaagttgac cagtccctat aaaactattt
     6601 ctattggcca taaatggagg taagacttcc gtatagccat gcttagctgt atgagtattt
     6661 aaaaagaaat tcattaaaga tctttctaat ctagctccta atcccctata taaagtaaac
     6721 cttgacccag ttattttccc tgctctttca aaatctaaaa tacctagacc tgtacctata
     6781 tcccaatgcg ctttatgctc aaaatcaaat ttagtaggtt ctccccaagt tcttatttga
     6841 acattgtctt catctgtttc accttgtggt acctctggat gaggaacatt tggtattctc
     6901 attaatgtat attccatttt tgcttctact tcttttactt tctcatcaat accttttatc
     6961 ttatctgata actctttcaa tcttgccttt tcttctgtta catcttttcc ttcttttatt
     7021 aattgaggta tttttttaga atttacattt aactcatttt tcataacttc aacttcttga
     7081 agtatttctc ttcttttatt atctaattcc accacagcat caaggtcaaa ttctctttca
     7141 cctcttcttt ccatagcttt tttgatatca tctagatttt ctcttattct tttaatatct
     7201 aacatattaa ttcctcctaa taattttgat aatataagtt ataattccaa cttaatttac
     7261 aaacattata cttgtaaact cttagtttaa acaaatttta aaaataaaaa aagacctccg
     7321 tttaccctat aaaagggacg aaaatctttt atccgcgttg ccaccctaat tgactatact
     7381 aaaatgtata atcctctcag acctataacg taggtaaacg tctagcttta actagaagct
     7441 ctagagtaga ttcaaaaacc attgtaatga gttttcacca tccactcatt ctctgaatac
     7501 aatctgtttt ttactatttt ccttcacagc tttttaacta attgttttat ttgataatca
     7561 ttatattata tatattaaca tctttcaata ctattattca aattttttta gaattttctt
     7621 taatttttta tattaaattc attttttcta tttaattaag accttatctt ttatccattg
     7681 tatttagatt acctgtatta ttaaataata atgaagaagg aacaaatgga acttttatat
     7741 cattctcatc aaatttattt tttacctttt ccattacatc aaaatataca tcccagtaat
     7801 catcagtttt tacccaaggt ctagcaacta tttgcatggt gttatttcct atagagttta
     7861 aacctattat aggctttgga tcatttaata ttcttttttc gtttgtaaaa atttcattta
     7921 atatagactt aactacatct atatcactat catatgaaat attatatgaa aaatctattc
     7981 ttcttttgtt ttgatgtgtg taattaatta tattattact tgtcagttga aaattaggta
     8041 taattatagt tttattatct ggtgtcttaa gaacagtgct aaatatttgt atgtcagaaa
     8101 ctgtaccttc tacacctgaa ccttgaatat aatcacctat attaaatggc ttaaaaaata
     8161 aaataatcat accagagcct aaatttgata atatttcttt aaaagctaaa cctatactaa
     8221 atccagcagc tcctaacaca gctacaactg atgtagtttg tatccctata atacctaagc
     8281 ttatcaatga tataatagat aacatagata tatatattcc atatacaata aaattattta
     8341 cacctttact cattccatat ttgattagaa actttgaaac catccttctt actattttag
     8401 atatataaat acctatcaca aatacaatta ttgcatatat aatatttggt atattatcac
     8461 taaaattatc gagcatattt tctaaagttc tcttagttat attgctattt gttgaggcag
     8521 tcttagccaa tgataaaaaa ttcattcaac tcctccttat gataatattc cgttgtcctt
     8581 taactctttt actatagctt ttatagtttc ttcttttatt gcctcaattg tatgaatatg
     8641 gctacattct gtcagaaccg ataattgttt aaattcattt gtctcaactt tcttcataaa
     8701 gttgtctata tccattttag aataaatatt aagttctgca gttatctgac catatgttgg
     8761 atgatttacg atgacatctt ttataatacc acctaaatcc acaattatct ttaattcatc
     8821 ataaatttct ttagaatcct tatgattttt acactttatt tgttttgtaa aatacggttg
     8881 attatatatt atatatcctt gaggtgtagc tattatttca aatcctctag ctcttataag
     8941 ggctatatct tgaactatta cttgcctact tacatttaat agttcagcta gtgttccacc
     9001 ttttacagga tgcttagatt cttttaaaat atctattaat ttacttcttc tttcattaga
     9061 attcatatta caccttcttt ccaaataaaa actttaccta tactatataa ttttatattt
     9121 tatcttatta taaatcaata ttgactttat attctattta atcttaactt ttataataaa
     9181 taaaaaaaga ctacgtggct acgtcctact ctcccaggca gtttcccacc aagtaccatc
     9241 agcgctagag agcttaactt ctgtgttc
//
LOCUS       DAEPUT010000126         8961 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.130, whole genome shotgun sequence.
ACCESSION   DAEPUT010000126 DAEPUT010000000
VERSION     DAEPUT010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8961
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.130"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(111..719)
                     /locus_tag="KRL22_003564"
     CDS             complement(111..719)
                     /locus_tag="KRL22_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBH1273994.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(828..3566)
                     /locus_tag="KRL22_003565"
     CDS             complement(828..3566)
                     /locus_tag="KRL22_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBH1273995.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3714..4505)
                     /locus_tag="KRL22_003566"
     CDS             complement(3714..4505)
                     /locus_tag="KRL22_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1273996.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4541..5197)
                     /locus_tag="KRL22_003567"
     CDS             complement(4541..5197)
                     /locus_tag="KRL22_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1273997.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5190..6155)
                     /locus_tag="KRL22_003568"
     CDS             complement(5190..6155)
                     /locus_tag="KRL22_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HBH1273998.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6261..6367)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6657..7601)
                     /locus_tag="KRL22_003569"
     CDS             complement(6657..7601)
                     /locus_tag="KRL22_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH1273999.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNVVMNESTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSESIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKCCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKSKVLELYNHHCI"
     gene            7712..8179
                     /locus_tag="KRL22_003570"
     CDS             7712..8179
                     /locus_tag="KRL22_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274000.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICILSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8349..8948)
                     /locus_tag="KRL22_003571"
     CDS             complement(8349..8948)
                     /locus_tag="KRL22_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274001.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT         2913 a         1491 c          865 g         3692 t
ORIGIN      
        1 gtttgtaatt ctataaagtt atttttatca aactaaaaat tctataaaaa aataagatac
       61 atacctataa aataccttcc tatagataca tatcttacct atataaaaac ttattctata
      121 taaaaacgcc ataaaaaatc ttttgcttct tctgcataat ctatatttat acgtttacta
      181 gtttttatat ctaactcatc cttactaaat actttttttc ctttatcatc ataataaaaa
      241 tcacttatat ataattcttc acccattata ctcttactat ttagacttct atctattttt
      301 aaagctttgc aaagttttcc tggtccgtta gtaatatttt ttacttgata tttactcaac
      361 tcagtgtaag ctttgttgta tctattcata gatatctcat ctaaagaagt tataggctct
      421 acccctctta ttaatacaca ctctggcaca ttttctatat ttgcagataa attcaagcaa
      481 ttatacatac cataaattaa ataaacatat atatgtccac catctaaata taatggctta
      541 gttctatctg tctttttatt gccatataca tgtgctcctt tatcatttac acccatgtat
      601 gcttctgtct ctatgatttt ggtaacaatt actttatttt catatttcct tattagatat
      661 ttacctaata ttgatttggc taaatcaatt ccattttttc taaaaaaatc cttttccaaa
      721 atttcacctc ataaaattta tttaaaacgc atcaaataca actaaagtaa taaataaaat
      781 taactcttat taatgtgata tatataaaca ataaatttag acatttatta tttatatata
      841 tcaaaaaatt ctatctcaaa cttttcaata ttatcattgt aatttgaatt atcatatact
      901 tcttcaacaa cctctttaat tgggaatata acttttacat tagttccttc tcctacctta
      961 ctatctatgt aaatcttccc attttgaatt tcaatcaatg attttgtaag gcataaacct
     1021 ataccacttc caaattcatt tgatatacca ctgttttcaa tttgtttaaa tcgattaaat
     1081 atatcattta atttttcttt gtctatgccc actccagtat cttttataat tatctctact
     1141 gtttcgtctt ttttatatat acctacaagg atttctcctc cttctaaagt aaattttata
     1201 gcatttgata atatatttag tattattctt tctatcgatt ctgggtcaag ccctaccata
     1261 acagtttctt catctgtatc aaaaattaaa tctattcctt tagacttagc ataactacta
     1321 atagatgtaa ctattctttc tgttatgtca ataatatcaa aattaactgc tttaatctta
     1381 tatatgtctg acttaacttg agaaatattt attatattat ctattaatct caataatcta
     1441 aacatatttt gtttagttat ttttatatgt tcttttagta tatcctgaaa atcaattatt
     1501 tttccttttt tataaaggtt ttcaataagt tgaactgaac tatatatatt atttaaaggt
     1561 gtcttaagtt catgagatat attagcataa aactccatct tcatttggtc atactgtctt
     1621 tgttttatta atgctttttt aagtctttca gactctcttt gcacacttaa atctttaata
     1681 attctcactc tacttctttt ctgtccaaag tataatgttc ttgatatcat ttttacttct
     1741 ttaatgtgat tattttcatt tactatatgg atactcttct ctctttctcc tatatttaaa
     1801 ttgtttatgt atttttttac taatatattt ctatattttt gtgttgtaac tcctaataca
     1861 tcactagaaa ttccgaacaa ctctctaaat gctctatttg tatatagtac tcttgatgta
     1921 cttaaatcct caagaaaaat agcctctggt ataacatcca gtaatttttc atatattatt
     1981 ttttgttcat ttactgttct aagaatattt atctctttag ttatatctct aaatgtaagc
     2041 aatttaaaga gtttattatc tgaccaatag tctccaactc taacttcttc aacatgctct
     2101 tcaccttctg agtcagacat cacaaaatta actatacagt ttgctgtgtc attgtaactt
     2161 actatttcag ctttcttttc ttgtgttaga tttaatcttt taaactccct attgtcaaag
     2221 aaatctatgt taaaagtttc aaaatattgt tctaatgtca tatcgactaa atcacttgaa
     2281 acacatttaa aactcttttc atatttttta tttatactta ttaccttatt cttctttatg
     2341 ccaccttcag cacttcttac aagtatagga gatggaatat ttagtataat gttttcatag
     2401 tctttattta tatttcttat ttcttcatct attttgattt catttgtaat atcatttaaa
     2461 cttattaagt aattgctttc atctttatta ttacttaaac ttaacaaata aattttatca
     2521 tttaactcta ccagtttatc aattatactt atatcgttat caaatttctt caatttttca
     2581 gcaacttttt catcttcctt tataaaagtt aatattttat aataattatt catatccttt
     2641 gaaaattcat ctttaaattt attatttgtg taacttatat taaaatcata gtctgttact
     2701 atccatacat ttggtattgt atccagagct tgtctaagta attcttttct ctggtctatg
     2761 tagtttttta atgttctttg tataatcata tccttttcta ttgctaaatt tatctttcct
     2821 aattgctctg actttttact taatttttta ttgattgaat caagttcata atatggatac
     2881 actactctat tattaagact gtatacatat acataataag tatggttaca taatagtaaa
     2941 tatattactc ctattaatct atctgaatct actatattaa tcttagaaat tgctacaaaa
     3001 catataatag ttgtaaaaaa aacaaaatat gttaaatctt ttattaactt atagtgctca
     3061 atgttactat caagtttatt caacaaatat agtaaattaa acatagatat acaaatatta
     3121 attaatataa taatcatatt ccagttaata tcactaaaaa tatttcttat aaagtaatct
     3181 aatatcacaa aagcactata aaaaattagt attgggctta ttcttagttt ttttacttta
     3241 gaaatggtta agtatataaa agtagacata ttaattatgc ttaagttaag caatacaatt
     3301 tggaattttt gaatttttaa atttactact cctaaaatac ttacaaaaac taatacaaga
     3361 caccctactt tcaatatatt tataaattca tctgttttaa agctacttat ataaactata
     3421 gaatatccaa atatccaaag taaaattatt ctatacatat ttatagaaac tgtatacaaa
     3481 tttatattta aaagtgcaat aaccaaaaat aacccattag ctagtatata gaccttattc
     3541 ttacttaaag ttcctttaga ttccatattc cccaccactt cttcattttt atatagtttt
     3601 acctataaat atgttaccac aattcttcca aaaaatttgt cactttctag ttataaaaaa
     3661 aaatgagtaa atatttttaa ttttactcat tttgtagatt ttgtatattc agtttaaaaa
     3721 gctggaacta tacttccttt atattcatct tgtataaatt ttttaacttc tttactattc
     3781 atagcctctg ataaagcctt aatcttatca ctatctttat tattttctct acaagctatt
     3841 atatttacat atggagaatc acttgattct attactattg catccttagt aggatttaag
     3901 ttagctgtta aagcataatt agaatttatt actgctccgt caacatcttt taatactgtt
     3961 ggtaattgct ctgcattcat ttcttttatt actatatttt taggattttt agttatatct
     4021 tttttagtta taagctctcc atcttttact tctatcaatt tattttttgc taataattta
     4081 agtgctctag ctccattagt tgcatcattt ggcacagcta taacagctcc atcttttaat
     4141 tcatctaatg acttaacttt ttctgaatag aatcccattg gctctatatg aactttagat
     4201 gtataagtaa gtttatatcc tttctccttc acagtttcct ctaaaaatgg aatatgttga
     4261 aagaagttag catccaaaga cccttcatct aaagctgtat ttggaagtac ataatcatca
     4321 aatattttta cttctaaatc atatcctttt tcttttaaca aaggttttgc aacttccaat
     4381 atctttgcat gtggatttga tgaagctcct actagtattt ttttatcctc tttgtttgaa
     4441 caacctactg ctgatattgc tattgctgac accaatgcta ctgataataa tttctttaat
     4501 ttcattttta ctccccctct ttaaaatgtt tataattaat ttattttagt ttcttataag
     4561 ccagatttcc tactccctgg attatctgaa ctaatattat aagtgctatt acagtatata
     4621 ccattactgc tgtatcaaat ctttgatatc cataaataag tgctatatta cctaatcctc
     4681 cagctcctac tgcacctgcc atagctgtat aaccaagtat agatattatt gataatgtaa
     4741 ttccagatac tattgaaggc atagcttcct ttatcataac tttaaatact atttgtcttt
     4801 ttgtagctcc aaaagatttt gctgcttcta tcaatccttt atcaacttca tttaatgagc
     4861 tttctataat tctagcgata aacggtgctg ccccaatagt tattggcact attgcagcag
     4921 tttcccctat acttgttcca acgattaacc tagttattgg aatcattgca actataagta
     4981 tcataaatgg gaaacttcta aatatattta ctataaatcc taatgcacta tttattgtgc
     5041 tatttggttt taatccatct ggttttgtaa ctactaatat gattgctaat ataaatccta
     5101 atattgttgc cactatagtt ggtactataa ccatatacaa agtttgtaac aatgcatttg
     5161 gaaatagtgt tgttaaaaag tcaattaaac tattcattta tcatttcctc ccatcttatg
     5221 cccttactag ttagatattg ttttacttgc tctccacttt tatctgaaat gtttataata
     5281 agtgaaccta aaatatcatc tttaaattgt tctaatttcc caaatattat agacacatct
     5341 atatttagtt ctcttgccat agtcgtaata atagcttcat tagaaatatc tttagggaat
     5401 agtatcttta tatttgttcc ttttggcaat attatacttt cttcacctat taattttcta
     5461 agtcctttag tatttcttaa gaatatttct tctgtatctc ctacctctaa tacttctcca
     5521 ttttccatta ttgctactct tccacaaatc tgctttataa cttccatttg atgagttaca
     5581 actattattg ttattcccaa ttttttattt atatcttcaa gcaatgaaag aattgacttt
     5641 gtagtatttg ggtctaatgc tgaagtcgct tcatcacaaa gaagtacttg tggatttagt
     5701 gctaaagctc tagcaattgc aaccctttgt ttttgtccgc cacttagatt tctgggttta
     5761 tcatttttct tttcagatat tccaactact tctaataact ctaaaactct ttttttaatt
     5821 tctgcctttg agtatccaaa acattctaat ggcaatgcta cattatcaaa tacagttttt
     5881 ctttcaagca atgaaaagtg ttgaaaaatc attcctaact cttttcttaa atctctcatt
     5941 tgcttttcat tcaatgactt tacttcttta tcagaaacaa gtacactgcc ttcttggtat
     6001 tcttctaatc cgtttataca tctcagtagt gttgatttcc ctgcaccact atgacctatt
     6061 attccaaaaa tttctccaga ttctatttca atacttacat ctttaagcac ttgaatcttt
     6121 ccataatact tattaacatt ttttatgcta atcataaaat ttcctcccat atattctgct
     6181 cagtttttat gtttatcctc tcttatgtat tacaacaaaa taaaagcccg agtataaact
     6241 caggcttaga aagctattta tactcatcta tcaactatat tagttgcagg atttagcacc
     6301 aatgtatata aaatatactg gttgccgggt ttcaaagggc cagtccctcc accactcttg
     6361 ataagacgtt atttaattta attctattat catttgttgc tatgttatat atgatatatt
     6421 cattaatagt atttgtcaat aaatttattt aaatttttta ttttttatta tcgttaatta
     6481 actattttta attagttttc tagctcctaa cactttatat tttaatgtct atataactat
     6541 agaacatcat tataagaaat aaattaaata acatcaatct atctaaatca tctgtaaagt
     6601 aaattaagaa aattaacatt ttatccaaac tctatcctac tattaaataa aataatttaa
     6661 atacaatgat gattatatag ctctagtact ttagacttta tcaaatgttt aagttctata
     6721 ggttctatta ttgtagcatt tttcccaaaa gttaaaaaat attcagccac ccagttaagt
     6781 gtagattttg gtatatacat atctatgtat ccacctttag acaagatttt caatcctctt
     6841 gccaacaaaa attctgtttc acaacatttt actccctcat ctgtcaaatt aattttaata
     6901 tgataatctg tacctacttc catattctta agataatcat gtatagaaga taaaacctta
     6961 tatttcttac ttgataagtt ttctatactc aaaatcttca caattctgtc tacacgaaat
     7021 tccttaatag attctgattt tatacagtaa gctggacaat accaaagtcc attcatggca
     7081 tacaaaccaa taggaacaat ggtacgtaca ctattttttt gctttgatga atattcaatt
     7141 ttaattgtag attcattcat tactacatta aacaattctt tcaataatgg tgttgaacag
     7201 tgcctatctg gtgtccaaaa aacaaattta cgccttatat tctcaatatt atattgaata
     7261 tcatttggta tacaatttaa aaattttttt aaaacagaaa tagtttcttg ctcaaatggc
     7321 aaatcattat aatattctag tgactgatat gcaaagaata tagattttac ctcactttct
     7381 gaaaatgcaa tcggtggaag tatacgctct ttaagtacat gatatccacc agccgctcca
     7441 acttttgaat ataatggaaa tccaatactc tccagcacct gtaagtctct tagtatagta
     7501 cgttttgata cagaaaattc ttctgctaat tctcctgctg taaaacttct ttttgcattt
     7561 attgttatca tcagttcaat taaacgctca gctcttgaca tatttatact cctaatttaa
     7621 atatagtgac aataattgtc actattatat gataagatat tcttacattt aaagcaataa
     7681 taatagtaaa gaaagaaggg actgatactt tatagaaaat aatactatta aggctgatga
     7741 tattatcaat tattgtctat caaacttaga tgatgtttta ttaatgaata gttgggggga
     7801 acgagcaatt tactacaatc ctaatggtat tttaaagcga ggagtatatg ttcttaccat
     7861 taaagaaaaa gacagtaatc atgataaagg ttcgttggtt agtcgtccaa atgtataccg
     7921 tgtgaatata ggattaaaaa aagaaacttt tattgaaatg tttggatata ttccaaagcg
     7981 tccaggtgta ggtcaaatag ttgatatgga ttttgatttt acaaaattgg acacaatcat
     8041 gccacatcct atctactcat ggatgggatg gatatgcatc ctaagcccta ctgaaaagac
     8101 atttgagaac tttaaaactt taataggaga atcttacaat tttgcaaaac aaaaatttaa
     8161 aaagagaaaa aacaagtaaa aacatatgaa aataatccct aaataaatta taataaaaat
     8221 attaaggtta caagataaaa attaatatct taataacatg caaaaaagcg aagccaaaaa
     8281 atgtattatt tataaggctt cgctatatct caaataattt atttcaaatt tcaaaactat
     8341 ttattctatt atttcttatt atttcctgtt attcctaatc tatcattcat atcttttatc
     8401 atttttctaa aaccactacc tatatcattt ccaacatctt cagttccatg aactaatttt
     8461 ataaagtcat tttgaccttt tttcatatct tcatcagata ccttatctaa tttttctatt
     8521 ctcttatcta tgtcttttac taatctttcc ccttcagcga ttaggtcatc attcattttc
     8581 tttaactctg tatcttctgt tttaccatct tttttaagag atgttacaaa tgattgtatt
     8641 ttatctctac tatctttata tgcagccttt acatcactta gatatttttc atttcctgga
     8701 tattctttat ctttaaactg attatttata ctttctggag tatcataaat agaatatcta
     8761 tttagacctg ctatataatc attatagctt gttgaataat aattcatata tccttcatta
     8821 ttatttacag attcattagg attttttcct gtattttcac ttggtttttc attattttta
     8881 gtacatgcag ttatacctat agctaatact agtgctaatc ctacaaataa agttcttttt
     8941 aatttcattt ttattaccct c
//
LOCUS       DAEPUT010000127         8919 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.131, whole genome shotgun sequence.
ACCESSION   DAEPUT010000127 DAEPUT010000000
VERSION     DAEPUT010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8919
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.131"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(82..1854)
                     /locus_tag="KRL22_003572"
     CDS             complement(82..1854)
                     /locus_tag="KRL22_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HBH1274002.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYFSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKDEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(1868..2797)
                     /locus_tag="KRL22_003573"
     CDS             complement(1868..2797)
                     /locus_tag="KRL22_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1274003.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            3026..3214
                     /locus_tag="KRL22_003574"
     CDS             3026..3214
                     /locus_tag="KRL22_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274004.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            3207..3908
                     /locus_tag="KRL22_003575"
     CDS             3207..3908
                     /locus_tag="KRL22_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1274005.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHGGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            3910..4833
                     /locus_tag="KRL22_003576"
     CDS             3910..4833
                     /locus_tag="KRL22_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1274006.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            4990..5913
                     /locus_tag="KRL22_003577"
     CDS             4990..5913
                     /locus_tag="KRL22_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1274007.1"
                     /translation="MNDFVIETKQLTKTYGDQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVIVISSQLCNDTLEDYFKKITGGEGIA"
     gene            5906..6643
                     /locus_tag="KRL22_003578"
     CDS             5906..6643
                     /locus_tag="KRL22_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1274008.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            6654..7427
                     /locus_tag="KRL22_003579"
     CDS             6654..7427
                     /locus_tag="KRL22_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1274009.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYVDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPITAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(7968..8576)
                     /locus_tag="KRL22_003580"
     CDS             complement(7968..8576)
                     /locus_tag="KRL22_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBH1274010.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(8754..8870)
                     /gene="rrf"
                     /locus_tag="KRL22_003581"
     rRNA            complement(8754..8870)
                     /gene="rrf"
                     /locus_tag="KRL22_003581"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         2941 a         1481 c         1281 g         3216 t
ORIGIN      
        1 ttctgtgaaa atttctacat tttttataaa ttttattcat ttttatattt ttatgtatat
       61 aaattctttt ttgtaagttt attaatttct aattatcttc tttaaataca ttgaaactac
      121 atcagaaaat ctagttatat ctcttgaata tataaaatca tttccatata ttaatctttc
      181 agcttcaagt tctgattctt ttcctgtaaa tactcctaat actaatatat tttgctttct
      241 agcttttctc acttcattgg ctgtatctct caaaccaact atacccctat aagccttttc
      301 tcctcttaat gttctctcac tactttttcc tatctttaca tcatttggtc ttccatcgct
      361 gagaactatc aggattttat tttcttcatc tctatttatt agaccactac atatagattt
      421 tattgccaaa ccatctctat tattaccagc acaaaaatat tcaaatatat tttcactatt
      481 ttttatacta tcatcataat ctttaaatct ttttaatatt gtatagtcta aaaaactaga
      541 aaatcccatc actctatttg gtatgccaac ttctgttaga gcatttgcaa ttatgtaagc
      601 ttgaattgcc acatttccct gatttctact ttgagagcca cttgcatcca ataatatatc
      661 aataacgtat ttcccttttt cattttctat atctttataa aatattttat tattattact
      721 tctaccaact ctccaagctc tatttgctaa tatagtacca caatcagaat atactctact
      781 tttagcattt tcttctatta aaattcttga cagactctct tttaatctct ttatttgctg
      841 tctatacatt ctagcatgtt ctctaaattt tcctaaatta ttttcttttt gtcttgttac
      901 atattttagt tgaaatacat tattacactc acttctaaga actccatctg taaagtgtat
      961 tctacaacct tcatgaacat ttctacaatt ttgtgtctca atttttttaa tttcatcttt
     1021 actcaaataa gtttttccat aataatgttc tatttttgaa tatatcttat ttgcagtgtc
     1081 ttcatcaaca tatataactc ggtctgctga attgctacat ttagaatcat caaaatcccc
     1141 tacaccttct acaagcatgg atgaagatat tgaatctata tcactttcaa taatattttc
     1201 ttcttcatca ctataaagtt cttcatacat gaaatcagca aatgtatcaa aatttacttc
     1261 tacactttct acattatttt catcaataag actattttct tctccattta atatgtattc
     1321 aaaataagtt aaatatataa catctaatgc ttttaaaatc tccataatat cttgattggt
     1381 atctatattt cttatatcat taactattct tctagtcata ctatctaatg ctgggtgctt
     1441 gtccatacta taaagtacaa atgtgtattt aattttatcc ataatattat cattgtgtat
     1501 tttggtaaaa cgtgaaacaa tatctttata agcatttctt cttatgtctt ctatccctgg
     1561 cctatcttta atgacctttt cttcaactat tgtatttaat atgacttgaa ttagacccag
     1621 tataatatct ttgttgtatc cttttcttat tctatttgta agatattttt taactatatc
     1681 ccaatctaca tactttcttc tagcacctgc aattattgcg aaatatagac ctatttcttt
     1741 tgaaaagtaa tctttttctg atatatctat actttcattg taatcaccag ctattgtcca
     1801 tgataggtta ttagctctat tttcaaattc ataatcatca tatatccatt tcataatctc
     1861 acctatatta aatatgactt attggaaaca catctatact ctcccattta ttaggtattc
     1921 tagttttaat tacatctcca accatttctt tctcatatac atcaaaagtc tttcctgtaa
     1981 gtcccatatt aattgcaaga gttggtttta atcctcttct tatagtctta agagatgcca
     2041 taagaccacg taaatcaata gctttactag atatctctcc attttgagac ttcaattgta
     2101 aatctaaaaa tattcctgca aagtgtatta atttttcttc atcagcatct gaaaattcat
     2161 tttttaaaat catcattaac ttatcttctt ctataggagg aatatctatt accataaatc
     2221 tagataccag tgcttcatta agttcttttg ttcctgcata ttcataattc atagtcccaa
     2281 taaatcttgt tgctggatgt agattgactc tctcataccc aggtacatca attattcttc
     2341 tatagtctaa agctgaatgt accacaacta tagcatcatt ttttgccata ttaatttcat
     2401 caaatacccc aaaacctcca ttaatagcac actcataaac tgagcctctt ctaagtttaa
     2461 cttcattgtc tataaatgta tctgtaccta taagtgttga actgtctgta tttatatgaa
     2521 atgatgtatt ccactgaggt ctattaaata tttcccctag attatcagca agtaagtttt
     2581 ttcctgttgc ctttggtccc gataataata tattttcttc ttctaaaata gctgctatac
     2641 acatagacaa gatatcttta ccataaaaat aagttttaga ctttgttact ctgtattcta
     2701 aatctttttc taatccataa taatttctaa aatacagtac atcttcaata agtttttcat
     2761 ctaccccttg cacccttaga ttatctatta tatccatatt tttacccctt ttatataaat
     2821 agtatttgtt tcatttctta tcaccatttt agcataaaag gatataagct aaaattgatt
     2881 ttttaatctc ccccatttta agtaaaacca tgcaccattt tatcactaca aaattaagag
     2941 tactacttac tgatatttct tgattttatt cgtctatacg tatataatat atgctaataa
     3001 attatgagga aaggatgatt gaaatatgga atatatgtct tgcccagaag tagcaaaaaa
     3061 atggggtatt tctgaaagaa gagtacaaaa actatgtgaa gaaagtcgca taccaggagt
     3121 ttcaaaactc gggtatatgt ggctgatacc aaagaacgca gaaaagcctg ttgatggtag
     3181 aacaaaaaga agaaaggaag tacaatatga atagcgtttt gattatagat gatgacaaag
     3241 aactttgtgc tcttatgaaa aaatgtgttg agcaagaaaa tttatctgct attactgcac
     3301 atggtggtgc agaaggtcta catttagtcg ataaaaatag acacacactc tctcttgtaa
     3361 ttttggacat aatgatgcca gatatagacg gttttcaagt tctgaaaaaa attagagaaa
     3421 caagtaatat tccagtaatt atgcttactg ctaaaaatga cgaggatgat aaagtttccg
     3481 gactacgttt aggtgctgac gattacctaa caaaaccgtt cagcataaac gaacttatgg
     3541 ctcgtgtcaa ttctcttatt cgtcggtata ctatgttaaa ccctgctttt ataacagaca
     3601 cagattgcat aataataaat ggcatgatta ttgacaagac aaaccgaatt gtttctgtca
     3661 ataatattcc tgttcaactt acaagcaaag aatttgattt acttgctttt ctggcttcta
     3721 ataagggacg ggtgtttacc aaaaaacaga tttatacaca agtatgggaa gaagaatatg
     3781 cttttgacga tagtaacatc atgtctttca tcagtaaatt gagaaaaaag attgaaccag
     3841 accccaacca tccattttat attttgacag ttcgtggtgt cggttatcgt tttaataagg
     3901 aggcttaaca tgaatacaag tgtctatctg cttttgatat tggctcttag cctgattatt
     3961 atagcgtacc ttgtttctgt cctgctacgt gtccgaatac aacttacact tataaaagat
     4021 gctttagagg atataaaaaa tggaaacctt aatcgacgta ttttaacaga tgaaaacgac
     4081 attacaaaac aaatttgcta tgatattaac gaaatagcaa tcaatagcca atttcaactt
     4141 attcagcaaa aacaatcaga acaagcctac aaacagctaa tgacaagtct ctcccatgat
     4201 gtaaaaactc cacttgcttc tttggtcggt tatttggaag cagtagaaag taaaattgtt
     4261 gtaggagagg aaaaagacga gtatatccat gttgcgtcta ataaggctca ttacttaaag
     4321 aattttgtag aaaatctatt tgaatgggta aaattggatt ctaaggaaca agtttttcat
     4381 tttgatattt ttgacttgaa tgaattatcc cgtaatatta tatctgattg gatacctgtt
     4441 ttagaaagca gtcattttga atatgaattt gatataccag aaatagagta cttcttacgt
     4501 atagacgcaa atgcatatac ccgtatcatt aataacctat tacaaaatat tattacccat
     4561 agtagtggca acaaaatgac attgagaatt tttgaaaaca aagagcaagc tcaaattata
     4621 ataacagata atgggaaagg tatatcttca gacaatctcc cacatatttt tgaaaggttg
     4681 taccaatgcg accattcacg agcttcaaag ggaaatggtt taggcttggc gattgcaaag
     4741 gaacttatta acgctcataa gggaaatatt accgccaaca gcactcccgg tatgggaaca
     4801 gaatttacaa tattgcttcc taaagccctg taaaagtacg aggctttctt actctaaaac
     4861 aagataaaag caagattatg gcaaggtttt ggcaaggttc atgttttata attctaattg
     4921 tagttgattt tgacgttgta tcaactatct tttgtagaaa caaatttatt aaaagtgagg
     4981 aaattatata tgaatgattt tgtgattgaa acaaagcaac ttacaaaaac ttatggggat
     5041 caaacagtag ttgacaaagt caatctccat gtaaaaaaag gccgaatata tggtctgtta
     5101 ggacgcaacg gagctgggaa aaccacaatt atgaaaatga ttttaggatt gacttcaatc
     5161 acgtatggcg aggtagatgt atttggagag aatattaagg gacgtgaaaa acaagtatat
     5221 ccccgtatcg gtgcaattat cgaaacgcca ggattttatc ctaatctgac aggaacggag
     5281 aacttggaga tttttgcaaa actgcgtggt acagccgccc ctaattctgt aaaaagagca
     5341 ttggaaattg taggcttacc ttataaaaat aaaaagctgt ttagtaaata ttcacttggc
     5401 atgaaacagc gacttggtat tgccaacgct atcctgcatg acccagaact gttagtttta
     5461 gatgagccaa ccaatggtct tgaccctatt ggtattgcgg agatgagaaa gtttattagg
     5521 gacttgagcg ttgagcatgg aaagacaatt cttatttcca gtcatattct ttcagaaatc
     5581 tcattgttgg ctgatgatat tggaattatc gaccacggtg ttcttttgga agaaagtagt
     5641 atgagtgaac tagaaaagaa aaacagtaaa tatatcctgc tacaagtttc agatattccg
     5701 aagacatcac ttattttaga gcgtcaattt aacacgaagg attattccgt tcaagatgac
     5761 tacacgttac acctttataa cactaatctg gatatgggtg aaatcaataa agcacttgta
     5821 atgcagaatg taattgttat tagttctcaa ctttgtaatg atactttaga ggactacttt
     5881 aaaaaaatca caggaggaga gggcattgct taaacttatt caaacagaat ttcttaaact
     5941 gcgtcgtagg aaacttattt ggctgatgtt gttgtctgct ctcattatgc cgtttttcgc
     6001 actactatac ttcaattatt ttggtaaaac aggtgttgag ccaacaaagt tttataaatg
     6061 gtctgcattt ggttatacac tttggattat tttgcccgtt gttttgggta tattttgcac
     6121 catgcttata cacgaagaaa accagtatga tatgctcaaa cagctttgga ttgtacctat
     6181 tagtaaaatg ggatactttt ttagtaaatt tttcgttgtt ttgatttact ctatttgttt
     6241 tatgctgatt acagccgttg cttctgtgtt atttagtgta ctttctggat atgtcgtatt
     6301 tagctgggca agcattttat atttgttgaa aaaatgtcta gaaattggtg taatcactgc
     6361 ttttgtaatg ttgccgattt tggcaatcgc tacatctcaa aaaggataca ttctcccaat
     6421 ttgtatcaca ttggtatatg ccttttccgg ttttgttata atgacaataa atatgtattt
     6481 acacccttta tccagtatgg gagttattat catgagaaat aaagacattc caggtcttat
     6541 attttcacag gaaattaatg tcccattagc atttctttgt atttgtattt ggagtattgt
     6601 atcagtattg tttgcaaaca ttgcactagg aagaagaaag tgaggtgtag ataatgtgga
     6661 aattactttg ggctgaatgc caaaaaattc gtcgttcaaa aattgtttgg attacagttt
     6721 ttgcatccat tatgatagca gtcatagttt ttgcaggagg gcaggatgta tataatgacc
     6781 cagatttaca ttatggctta aagagcgttt atgacggttc acggtatata gacaatgcag
     6841 gttggtatgt ggacgcagta caaccttggt caactttttt tgttcttcct gctgtcattg
     6901 ccctattagg aagctatatt atttgtcgtg aggaagagga ggacactatt aaatccctgc
     6961 gtcttattcc cataaatgaa acaaaattaa ccatagcaaa aatgattatt acttttatat
     7021 tcagtatact tctttatttg ttactcttta ctataacatt tttgactgaa tccgttttac
     7081 atttttccga tttatcgaca aaactggttt taagttgcat gaaagagtat tttcttgatg
     7141 gcataggtgt attctttgca atttctccca ttattgcctt ggtatcgcgc atgaaaaaag
     7201 gatattggct tgcattagta ttcacagaag tttattctat tgctggacta tttgcgggta
     7261 tgtcaaatgt cttacaaacc ttttttccta ttacggcaat atttaatatt tctggatact
     7321 atataactac tggagaaaaa attatgggga gtatcataag tttattactt tgtgcctgcc
     7381 tttctgcatt tatacttaaa gggctaaaac acaatgaaaa aaattgaaat aggtatatca
     7441 aaatgaaaaa gataaaaaaa ctgattattc taattgtatt cttgtttctt tttggcatgt
     7501 tacactgtta tactgaatgg aaattcaaca ataacccacc taaaggggta atagaaagaa
     7561 taaatgagtg gactaataag attggactgg attagtaact tatgttaatt atagtgaatg
     7621 taatattagc aagttattgt ttcgtatttt aatactataa ctttaaatat ttggttttaa
     7681 tcttccaaac gaatataaaa aaactgtcac agaggcaaca tatttttgaa tatttataaa
     7741 gtggtagttt tgattttcaa agctgccgcc ttttcttcta tataagcaaa cttatcctca
     7801 acaaagtgta aaacatggta cattttaaga aaaaagtacc acagacacaa gcaataaaag
     7861 aaacgccgag aacctacaaa aacgtagtgc ttatgcagat ttacgacgcc ttctattttc
     7921 tcaaccgtct taatgacctt gtacaaaaga aatttttcta atatttttta taatcttatc
     7981 ttgtgatgtt ttttatgtat aaatgactta ataacaaatc caataaaaat tatggatatt
     8041 ggtataatta gaacgaggaa tttataatca ttataatgtg acattattct tacccaactc
     8101 tcagaaaaaa tatatcctat actgattaat gaagtattcc atatagttat tcccacgata
     8161 gatgatatta caaaagttat aatattttga cctgctatac ctgctataaa agatatgtat
     8221 gttctacata aagggattaa tctacataca caaacagaaa tagaagagta tttattaaaa
     8281 taatcttgag atgcaaatat tcctttcttt gcctttggac atatctctat tattttattt
     8341 atgatagatt tacctcccca atttcccact gtataacaaa atatcgaacc aagtatacct
     8401 gcaattatac ttaaaattaa aattgtcaga aatccaaaat gatttcttgc agcaattgct
     8461 ccacataaag gtaaaacaac ttcgctaggt aatggaaaac aagcatactc aatcataatt
     8521 aatacaaata cagagattaa tccatattgt aaaataaaac tattgattac agacacttac
     8581 ttatctatct cctttcttat ttaaaggttt taagggtaca tgttctaagg attctcaccc
     8641 tatatttaaa gaatcaatct ctttaaacta ttatatgtat ttacacaaag catttataac
     8701 atactttaaa aatagtacct taaaataaga aacttaataa ataaaaaaag attacgtggc
     8761 tacgtcctac tctcccaggc agtttcccac caagtaccat cagcgctaga gagcttaact
     8821 tctgtgttcg gaatgggaac aggtgtatcc tctctgctat tgtaaccaca taatctttat
     8881 gcttaatatt tctattaagt ttttaataag tttatagaa
//
LOCUS       DAEPUT010000128         8632 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.132, whole genome shotgun sequence.
ACCESSION   DAEPUT010000128 DAEPUT010000000
VERSION     DAEPUT010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8632
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.132"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            167..1768
                     /locus_tag="KRL22_003582"
     CDS             167..1768
                     /locus_tag="KRL22_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HBH1274011.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSNKTV
                     LEGAKNITSVGEINEKVIQQCISASKSNGQPPTITVGSTEVYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINFYRKEKGKEPLVVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSNEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            1987..3576
                     /locus_tag="KRL22_003583"
     CDS             1987..3576
                     /locus_tag="KRL22_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp12"
                     /protein_id="HBH1274012.1"
                     /translation="MKVNKRVLSIGLTISLIMAGATNINALSSIEKIQGKDRYETAAK
                     IAQKQTYENVVLVNTDNTLADGLSASGLAGTVKAPILLSQRNSIPSDTEKMLKDVKKV
                     YIIGTEDSIGKSVENELKQKGIEVKRIGGNDRIETSYLIAKEIASIKPIDKVFITNGY
                     TGEADAMSASSVASRDGAPIILTNGKNVPFEKKEGVQCYALGSEEIISNDLVKKTNAV
                     RLAGEDRFETNKKVIKHFYSSAKEFYLSKGYQLVDAVAGSSIAKNAPIVLVDGNSDKS
                     VLRSADKITALGGIDEKTLEQCLSASSLDASAPTITVGNLNIYQGDKFDISKLNIVAK
                     DSNGNDLTPELIGNINTDKVGKYKVTIKATDIGGKTTSISVEVNVLEYKTNDMNSSEF
                     KRMVSSEMYNLVNSYRKEKGKEPLQVSKNLEGLSNSWSKYMADKGQFSHVIDGKKSVE
                     VFTGYGLRSEENIAFVPLVTKSTYTTKDARELANVIFTVWKKSDKYNENMLNSDFVYT
                     GFGLYILPNGEVYATQEFLNK"
     gene            3789..6116
                     /gene="slpA"
                     /locus_tag="KRL22_003584"
     CDS             3789..6116
                     /gene="slpA"
                     /locus_tag="KRL22_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HBH1274013.1"
                     /translation="MNKKNVAIAMSALTVVGSAAPIFADAVPSESNANNYTVVKDKYK
                     DIYDEIEKLVKENDQIISDYKALEGNGAKSDDVIWSELVNKGAVNVIKMKVNEVAGDS
                     NKDSDDIPKVPETTIRTGTVADKKYVEDKLKNLDSDQYVDFSIQLKGTKGESTTKYTN
                     AELTTLANNSGKEILDGIKATTPERLTENGVLSQVAKDAVSGKTEAATAEVLASYFTV
                     SSSLNKVTVSFAEPSTGKVLTTDAANTTVESSGVKNKISAETGYNTIDLTTESNRLDF
                     SKPKFTAGKFSGFEEKAPVDGDVTPGKTYNVRVINAKQSNIKATDYDGIKAIVQKYDF
                     DGAYIDKVYKEVDKLNKEDKLDGSAYDIDGTYKAVFYATGKRLQGFSSYGKNFTKDEP
                     QGGIAVGDAVYKLVIESDDEEDFVDGIEDLKDLNNSYTDVISIAGNDRIETAIELSKT
                     YYNSTDKDALYKNEVNNVVLVGSQAIVDGLVASPLAAEKEGPLLLTSKEKLDSSVKSE
                     IKRVLGLSSTSSINSKKKVYLVGGENSISKDVEKAISDMGVKVERLSGDDRYSTSLKI
                     ADEVGIDNDKAFVVGGTGLADAMSIAPVASQLDSSKDATPIVVVDGKADKLSTDAADF
                     LDGASKVDIIGGVNSVSDKVKDSIKDTIDKAPTRVSGDDRQDTNAQVINEYFKKENKT
                     VKNFFLAKDGSTKEDQLVDALASAAVAGNFGSVNGNQDKVSPAPIVLATDNLSSKQHV
                     EISKVVNDDASNKIVKVGGGIADSVVNKLKDLLGM"
     gene            6295..>8632
                     /gene="secA"
                     /locus_tag="KRL22_003585"
     CDS             6295..>8632
                     /gene="secA"
                     /locus_tag="KRL22_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH1274014.1"
                     /translation="MSVLDSILDKADEQEIKKLNFIVDKIELLENKMKSLSNEELKNM
                     TNVFKNRLSKGETLDDLLIESFAVVREASKRILGMRQYRVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGRGVHVITVNDYLAERDKELMRPVYEFLGMSVGVIIANQN
                     PSIRKEQYKCDITYGTNSEFGFDYLRDNMVTNLSNKVQRTLNFAIVDEVDSILIDEAR
                     TPLIIAGNGDEDLKLYKVADSFLKTIKEEDFEMERKDKTIALTESGISRAESFFGIKN
                     LTDIKNIELYHHINQALRAYKLMEKDVDYVIFKGEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKNESKTMATVTFQNFFRLYKKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNKPVIRGDLHDKVFKTEKEKYEAVVEEIVRIHKTRQPILVGTVSVEKSEKLSNMLKK
                     KNIKHQVLNAKQHDKEAEIISKAGKLEAITIATNMAGRGTDISLGAGDKVEESEVKNL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKTIEKLMKR
                     TISKENRVIESKNLTRAIERAQKGVEGKNFEIRKNVLKYDDTINEQRKVIYRERNKVL
                     NGEDIQEDIQKMVKDIIQVAADTYLIKRKRDYYGYFKYLYNTFMPNDTLLIPGIDQKS
                     VDEIVSSTYEISKRVYDLKKMMIGIEKVIEMEKIVLLKVVDQYWIDHIDAMEQLRQYI
                     GLKSYAQKDPFKEYALEGYDMFEVLNKNIREATIQYLYK"
BASE COUNT         3573 a          904 c         1651 g         2504 t
ORIGIN      
        1 taaaaagaag ttaaaaataa ttttttaaat ttaataaaat aaaacactaa tatatagacg
       61 agatatattc atatcatata tactctataa tatatggaaa ataaagagaa aataaatgga
      121 aaataatcac aatataaata taaaatataa aaatcatcag ggggatatga aaatgaacaa
      181 aaaaatatta tcattaggtc tagcagtatc attaatctta gtaaacttca aaagtgtaaa
      241 tgcatcatca gtagtagaaa aaatatacgg taaagataga tatgaaacag cagcaaagat
      301 agctgataaa cagacttatg aaacagtaat tttagtaaat acagaaaaat cacttgcaga
      361 tggattaagt gcaagtggat tatcaggagc tacaaaagct ccaatactat ttacacaaca
      421 aaataagata ccagcagaca caaatagatg tctaaaaaat atcaaaaaag catatataat
      481 aggtacagaa gatactataa gtaaatcagt agaaaaagaa ctagattcta aaaatataga
      541 agtcaaaaga attggtggag aagatagact aaaaacaagc tatttaatag ctaaagaaat
      601 agcaactata aaaaaagtgg ataaagtact actaactaat gcatatagtg gagaagcaga
      661 tgcaatgagt gtatcatcag tagctactag agatggagct ccaatcatac ttacagatgg
      721 aaagagtgtg ccttttgatg taaaaaatat tcaatcatat tgtataggtt cagaggagat
      781 aatgagtaat cctctagtta aaaatacaaa ctcagtaaga atagaaggaa ctgaccgatt
      841 tgaaactaac aaaaacgtaa tagactactt ttttaatagt gcagatggat tctatgtatc
      901 agatggatac caattagtag atgcaatagc agctgcacca cttactaaaa actctccaat
      961 ggtactagta aatgatggaa gcaataaaac tgtattagaa ggagctaaga atataacctc
     1021 tgtaggtgaa ataaatgaga aggtaataca acagtgtata agtgcttcaa agtcaaatgg
     1081 acaaccacca acaattacag ttggaagtac agaggtatat aagggtgaaa agtttgacac
     1141 tggcaagtta aatatagtag ctaaagataa cacagggaag gtattaccaa tagaagttga
     1201 tgggtttata gatacaaata gagtaggtac atacatattg acattaaaag ctacagacga
     1261 atggggaaaa agcacaggaa aaagagtaga aataaaagtg ttggatgaca aatctcatga
     1321 ttacaacagc ccagaattta aaaaaatggt atctactgaa atgtataact taatcaattt
     1381 ctatagaaaa gaaaaaggca aagaaccttt ggtagtatct agtaggctag aaggtatggc
     1441 aaatgcatgg tctaagtata tgatggataa aaaagtattt gcacattata tagatggaaa
     1501 aaatgctcca caagtatttt ctgaatttgg aatgagaagt gaggaaaata tagcatatat
     1561 ttatatagat tctaagaacg ttcaaactac acaagatgca aaagatttgg caaaggctat
     1621 atttgaggtg tggaagaaat ctccagagta caatgcaaac atgcttagta atgagtttta
     1681 tagtactgga tttgggcttt atatattatc tgatggtcaa gtgcatgcta ctcaggagtt
     1741 tttaaatggc aatgaaggta gcttgtaaaa aattccataa atcttgtttt tttgttaatt
     1801 tactgatatt ataaaatgaa aatcacatct aaagtacttt ttgtaatctg ttttgttatt
     1861 gatttacagg ttatggtatt ttaggtgttt tttgttttag tagtttataa attttgaggg
     1921 aatcactact gaggatgtaa tttatgatta gctgaattat ataaaaaaat tagtaggagg
     1981 agtttgatga aggtaaataa gagagtatta tcaataggat tgacaatatc attaataatg
     2041 gcaggagcaa caaatatcaa tgcactttcg agcatagaaa agatacaagg gaaagataga
     2101 tatgagacag ctgccaaaat tgcacagaaa caaacatatg aaaatgtagt attagtaaat
     2161 acagataata cactagctga tggattaagt gcaagtggat tagcaggaac agttaaagca
     2221 cctatattat tatcacaaag aaacagtata ccatcagaca cagaaaaaat gttaaaagat
     2281 gtaaagaagg tttatataat aggaactgaa gattcaatag gaaaatcagt tgaaaatgaa
     2341 ttaaagcaaa aaggaataga agttaaaaga ataggtggta atgatagaat tgaaacaagt
     2401 tatcttatag caaaagaaat agcttcaata aaacctatag ataaggtttt tataactaat
     2461 ggttatacag gtgaagcaga tgctatgagt gcatcatcag tagcatcaag agatggagca
     2521 cctataattt taactaatgg taaaaatgtt ccatttgaga aaaaagaagg cgtgcaatgt
     2581 tatgctcttg gttcagagga gataataagt aatgatttag ttaaaaaaac taatgcagtt
     2641 agattagctg gagaagatag atttgagact aataaaaaag ttataaaaca tttttatagt
     2701 tcggcaaaag aattttatct ttctaaaggt tatcaattag tagatgcagt tgctggttct
     2761 tctatagcta aaaatgcacc tattgtattg gttgatggaa atagtgataa gtctgtactt
     2821 agaagtgctg ataagattac agcactagga ggaatagatg aaaagacact agaacaatgt
     2881 ttaagtgcat catcactgga tgcaagtgca ccaacaataa ctgttggaaa tttaaatatt
     2941 tatcaaggtg ataagtttga tataagtaaa cttaatatag tagcaaagga tagcaatggt
     3001 aacgatttga caccagagct tataggaaat attaatactg ataaggtggg taaatacaaa
     3061 gttactataa aagctactga tattggtgga aagactacct caataagtgt agaagtaaat
     3121 gtacttgaat ataagactaa tgatatgaat agtagtgagt ttaaaagaat ggtttctagt
     3181 gaaatgtata atttggtaaa ttcatataga aaagaaaaag ggaaagagcc attacaagtt
     3241 tctaaaaact tagaagggct ttctaattcc tggtctaagt acatggcaga taaaggccaa
     3301 ttttcacatg taatagatgg taaaaaatct gttgaagtat ttactggata tgggttgaga
     3361 agtgaagaaa atatagcttt tgtaccactt gttacaaaga gcacttatac gacaaaagat
     3421 gctagagaac tagcaaatgt aatatttaca gtttggaaaa aatcggataa atataatgaa
     3481 aatatgctaa acagtgattt tgtatatact gggtttggat tgtatatatt gcctaatgga
     3541 gaagtgtatg ctactcaaga atttttaaat aagtaaaatt aaatttttta agttattaaa
     3601 tattgaaatt taagggtata aaaactcata tgcttgggaa aaataataat ttcaaaaaaa
     3661 tgacttgcaa aaagaataaa aatggattat tatagagatg tgagaaatat taggaatata
     3721 tggatgatta ttctatgtac ataataaaga gatgtaattt taatataatg ttgggaggaa
     3781 tttaagaaat gaataagaaa aatgtagcaa tagctatgtc agcattaaca gtagttggtt
     3841 cggccgctcc tatatttgct gatgcagtac caagtgaaag taatgctaac aattatacag
     3901 tggtaaagga caaatataaa gatatttatg atgaaattga aaagttagtt aaggaaaatg
     3961 atcaaataat ttctgattat aaagcactag agggcaatgg agcaaaaagt gatgatgtga
     4021 tttggtcaga attagttaac aagggtgctg tcaatgtaat caagatgaaa gttaatgaag
     4081 ttgctggaga ttcaaataag gattcagatg atatccctaa agttcctgaa actactataa
     4141 gaacaggaac agttgcagat aaaaagtatg ttgaagataa attgaaaaat ttagattcag
     4201 atcaatatgt tgatttttca atacaactta aaggaactaa aggagaaagc actacaaaat
     4261 atacaaatgc tgagttaact acattagcta ataattctgg taaagaaata cttgatggaa
     4321 tcaaagcaac tacacctgag agattaactg aaaatggagt acttagccaa gtagctaagg
     4381 atgctgttag tggaaaaaca gaagcagcaa cagcagaagt tttagctagt tattttactg
     4441 ttagttcatc acttaataag gttactgtaa gttttgcaga accttccaca ggaaaggttc
     4501 ttactacaga tgcagcaaat actactgtag agtcttctgg tgttaaaaat aaaataagtg
     4561 cagaaactgg atataataca atagatttaa caacagaaag taatagatta gattttagca
     4621 aacctaagtt tacagctgga aaattttcag gatttgagga gaaggctcca gttgatggtg
     4681 atgtaacacc aggaaaaaca tataatgtaa gagttataaa tgcaaaacaa tctaatataa
     4741 aagcaactga ttatgatggt ataaaagcta tagtacaaaa atatgatttt gatggagctt
     4801 atatagataa agtatataaa gaagttgata aattaaacaa agaagataaa cttgatggta
     4861 gtgcatatga tatagatggt acttataaag ctgtattcta tgctactgga aagagattac
     4921 aaggattttc aagttatgga aagaacttca ctaaagatga acctcaaggt ggaatagctg
     4981 ttggtgatgc tgtttataaa ttagttatag aatctgatga tgaagaagat tttgtagatg
     5041 gaatagaaga tttaaaagat ttaaacaata gttatactga tgttatttct atagcaggaa
     5101 atgatagaat agaaactgca attgaattaa gtaaaactta ttataatagt acagataagg
     5161 atgctcttta taaaaatgaa gttaacaatg ttgtattagt tggttcacaa gctatagttg
     5221 atggattagt tgcctctcct ttagcagctg agaaagaagg accattacta ttaacttcaa
     5281 aagaaaaatt agattctagt gttaaatcag aaataaagag agtattagga ttatctagca
     5341 cttcttctat aaattctaaa aagaaagttt atttagtagg aggagaaaat tctatatcta
     5401 aagatgttga aaaagcaata tctgatatgg gtgtaaaagt tgaaagatta tctggagatg
     5461 atagatattc tacttcttta aaaatagctg atgaagttgg aatagataac gataaagcat
     5521 ttgtagttgg aggaacaggt cttgcagatg ctatgagtat agcaccagta gcttctcaat
     5581 tagattctag taaagatgct actccaatag ttgttgttga tggaaaagct gataaattat
     5641 ctactgatgc agctgatttc ttagacggag cttctaaagt agatataata ggtggagtaa
     5701 attctgtatc tgacaaagtt aaagattcta taaaagatac tatagataaa gctccaacta
     5761 gagttagtgg tgatgataga caagacacta atgctcaagt tataaatgaa tacttcaaaa
     5821 aagaaaataa aactgttaag aatttcttct tagctaagga tggctcaact aaagaagatc
     5881 aactagtaga tgcattagct tcagcagcag ttgcaggtaa ttttggaagt gttaatggta
     5941 atcaagataa ggtttctcca gctccaatcg ttttagctac tgacaacttg tcttctaagc
     6001 aacatgttga aataagcaaa gtagtaaatg atgatgcttc taataagata gtaaaagttg
     6061 gtggaggaat tgctgattca gtagttaaca aattaaaaga cttattagga atgtaattaa
     6121 taaattatta tttatataaa aaagaatgga tgtatatcca ttcttttttg ttatcatatt
     6181 tactttttat ctaaagaaaa cctttcatta aatttcaata taaaaataaa tgtctactat
     6241 tatctaaaat taatgtataa tattagttgt atgaaaaaaa aggaggtatg gtatatgtca
     6301 gtattagatt caatacttga taaagcagat gaacaagaaa taaaaaaatt aaactttata
     6361 gtagataaaa ttgaattatt agaaaataaa atgaagtctc tatcaaatga agaattaaag
     6421 aatatgacta atgtatttaa aaatagattg agtaaaggag aaacattaga tgatctgtta
     6481 attgaatcat ttgcagttgt aagagaggca tcgaaaagaa tattaggtat gcgacaatat
     6541 agggtgcaat tgattggtgg aatagtaatt catcaaggaa aaattgcaga aatgaaaact
     6601 ggagaaggaa aaactttagt ggaagtagca ccagtatatc taaatgcact tacgggtaga
     6661 ggagtacatg taataacagt gaatgattac ttggcagagc gtgataaaga acttatgcgc
     6721 ccagtttatg aattccttgg aatgagtgta ggtgtaatta tagctaatca aaatccaagt
     6781 ataagaaaag agcaatataa atgtgatatt acttatggta caaatagtga atttggattt
     6841 gattatttaa gagacaatat ggttactaac ttatctaata aagtacaaag aactttaaac
     6901 tttgcaatag tggacgaggt agattcaatt ttgatagatg aagctagaac tccacttatt
     6961 attgcaggga atggagatga agatttaaag ctctataaag tagctgatag ttttttaaaa
     7021 acgataaaag aagaagattt tgaaatggaa agaaaagata agactatagc gttgacagaa
     7081 agtggtataa gtagagctga gtcatttttt ggaataaaaa atcttacaga tataaaaaat
     7141 atagaacttt atcatcatat aaatcaagct ttaagagctt acaaattaat ggagaaagat
     7201 gttgattatg tcatttttaa aggtgaagta atgatcgttg atgaatttac aggaagagta
     7261 atggatggaa gacgatatac agatggtctt catcaagcta tagaagcaaa agaaggtgta
     7321 gagataaaaa atgagtctaa aactatggct actgttacct tccaaaactt ttttagattg
     7381 tataaaaaac tttctggaat gacaggtaca gctaaaactg aagaaggaga gtttgagtct
     7441 atttataaac ttaatgttgt gcaaatacct actaataaac cagttattag aggagattta
     7501 catgataaag tatttaaaac agagaaagaa aagtatgaag ctgttgtaga agagatagta
     7561 agaattcata aaaccagaca accaatactt gtggggaccg tttctgttga aaaatctgaa
     7621 aaattatcta acatgctcaa gaaaaaaaat ataaaacatc aagttttaaa tgccaagcaa
     7681 catgataaag aagctgaaat aatatctaaa gcaggaaaac tagaagccat aacaattgca
     7741 actaatatgg ctggacgagg aacagatatt tctctaggag caggagataa ggtagaagag
     7801 tcagaagtta agaatttagg tggactttat gtcataggga cagaaagaca tgagtctaga
     7861 agaattgaca atcaacttag aggtcgttct ggtcgacaag gagatcctgg gacatcaaga
     7921 ttttttgtaa gtttagaaga tgatgtaata aaactttatg gtggtaaaac aatagaaaaa
     7981 cttatgaaga gaacaatttc caaagaaaat agagttatag aaagtaaaaa tcttacaaga
     8041 gctatagaaa gagcacaaaa gggagtggaa ggtaaaaact ttgagataag aaaaaatgtt
     8101 cttaaatatg atgatacaat taatgaacaa agaaaagtta tatatagaga aagaaataag
     8161 gtactaaatg gtgaggatat acaagaagat attcaaaaaa tggttaaaga tattatacaa
     8221 gtggcagcag atacttattt aataaaaaga aaaagagatt attatggtta ctttaaatac
     8281 ctatataata catttatgcc taatgatact cttttaattc ctggcattga tcagaaaagt
     8341 gttgatgaaa tagttagtag cacatatgaa atttcaaaaa gagtttatga tttaaaaaag
     8401 atgatgattg gtatagaaaa agttattgaa atggagaaaa ttgtcctttt aaaagttgtt
     8461 gatcaatatt ggatagatca tatagatgct atggaacagt tgagacaata tataggatta
     8521 aaatcttatg cacaaaaaga tccatttaag gaatacgctt tagaaggtta tgatatgttt
     8581 gaagttttaa ataaaaatat aagagaagca actatacaat atttatataa at
//
LOCUS       DAEPUT010000129         8515 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.133, whole genome shotgun sequence.
ACCESSION   DAEPUT010000129 DAEPUT010000000
VERSION     DAEPUT010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8515
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.133"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..510
                     /locus_tag="KRL22_003586"
     CDS             <1..510
                     /locus_tag="KRL22_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1274015.1"
                     /translation="SNLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIANQ
                     RNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRSISDVSWSEFIRQLEYKANWH
                     GRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWIYPSCNETHDRDINASINILKEG
                     LRLITIQNK"
     gene            946..1200
                     /locus_tag="KRL22_003587"
     CDS             946..1200
                     /locus_tag="KRL22_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274016.1"
                     /translation="MGNKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            1236..1559
                     /locus_tag="KRL22_003588"
     CDS             1236..1559
                     /locus_tag="KRL22_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274017.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIL
                     IDYII"
     gene            1833..1985
                     /locus_tag="KRL22_003589"
     CDS             1833..1985
                     /locus_tag="KRL22_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274018.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            2179..3102
                     /locus_tag="KRL22_003590"
     CDS             2179..3102
                     /locus_tag="KRL22_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBH1274019.1"
                     /translation="MVGAFVLPNYAITLSEMSNLWGNFTMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMALVSVLFFTYSIYLCATWKDKSLIADNKVETVKA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VEKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAITQEEYNKKKKELLE"
     repeat_region   3369..3984
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3369..3397
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            4175..4327
                     /locus_tag="KRL22_003591"
     CDS             4175..4327
                     /locus_tag="KRL22_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274020.1"
                     /translation="MKNCRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDE
                     ELEQKE"
     gene            4447..5260
                     /locus_tag="KRL22_003592"
                     /pseudo
     CDS             4447..5260
                     /locus_tag="KRL22_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            5312..5473
                     /locus_tag="KRL22_003593"
     CDS             5312..5473
                     /locus_tag="KRL22_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274021.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(5801..6265)
                     /locus_tag="KRL22_003594"
     CDS             complement(5801..6265)
                     /locus_tag="KRL22_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274022.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKNKILRERKYKKRR"
     gene            complement(6401..6718)
                     /locus_tag="KRL22_003595"
     CDS             complement(6401..6718)
                     /locus_tag="KRL22_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274023.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(7001..7297)
                     /locus_tag="KRL22_003596"
     CDS             complement(7001..7297)
                     /locus_tag="KRL22_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274024.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKSYLNRF"
     gene            complement(7316..7729)
                     /locus_tag="KRL22_003597"
     CDS             complement(7316..7729)
                     /locus_tag="KRL22_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274025.1"
                     /translation="MKVKSKRSFIVGIIVCMLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSADERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(7713..7946)
                     /locus_tag="KRL22_003598"
     CDS             complement(7713..7946)
                     /locus_tag="KRL22_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274026.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            8165..>8515
                     /locus_tag="KRL22_003599"
     CDS             8165..>8515
                     /locus_tag="KRL22_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1274027.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELE"
BASE COUNT         3428 a          918 c         1353 g         2816 t
ORIGIN      
        1 tcaaatctta agaagtcatt aaacaaactt gctaaattac aaagagaatt atcaagaaaa
       61 acaatcggta gtttaaatag aaataaagca agattaaaag ttgcaagact tcaagaacat
      121 atagctaatc aaagaaatga ttttctacaa aaactatcta ctaaattaat aaaagagaac
      181 gatattattt gcatagaaga tttacaagta aagaatatga ttaggaatcg taaactatct
      241 cgctcaattt ctgatgtgtc atggtcagag tttattcgtc aattagaata caaggctaat
      301 tggcatggta gacaaattgt aaaggtgggt aaattctttg caagttcaca aatatgcaat
      361 aaatgtgggt ataaaaacga ggaagtgaag gacttaaata taagagaatg gatttatcct
      421 agttgtaatg aaactcacga tagagatata aatgcaagta taaatatatt aaaagaagga
      481 ttaagactaa taacaattca aaataaataa cttatgtaag aaccgtagaa actacgggga
      541 tggcctgtgg agaattagta agacatatgt tagtatgcaa aattctgtga agcaggaaac
      601 ctgtgacttt agtcatggga ggttcaggct agtattacta ttgtattcaa aagctaaagt
      661 ggaaacctag tgaatatatg aatttagaag ttaatgagag agcattagca gccgactcaa
      721 tacttattaa aattgaagat gaagaagaag caatgaaaga agctgaaaga gagaaaaaga
      781 gaggtagaag aaggtagaat ttaaagttaa aatagttaca ttgctaatat atgaaaatgt
      841 tacaattttg gaaatagatg gatatatatg ttgtatagta taatgtagat aatatatcac
      901 caagtaaaaa acaacaaata aatctaaatt atgaggggtg tatttatggg aaataaagat
      961 attaaactta caatatgtat atttgctttt gtaattggaa taatagtgtt attttgctgt
     1021 ataggtctag gtcaatttaa tatggattgt attataaaac aaaatggtgg gtcaatagct
     1081 accgaacaat acaacatata tttagaacaa tctatttcac aatatagaaa ttttggttct
     1141 atactggttt tactaggagg aataggaata ctgtttgata aaagtgtcag aaaatactaa
     1201 aaaagtatat ttttatttag gatgtgatga atgatatggc aagagatgta tttagtgtaa
     1261 agatgacacc actagaagca cagaaaatgg tagaaaaaaa tttggaagca gatttagttt
     1321 ctgttgatat ttataaccta gaaaataata agtctataat agttacaatc tttgaaaaat
     1381 attatgcaag aagcaatagt gatgcaggtt tggtagtgat ttgtgaaaat actacaggaa
     1441 aaacacttgt taaaattacc tcaactggta gtgcaattgg actatttcag attgattggg
     1501 gaacaggtaa taatttgatt aaaagagtaa aaaaaatact tattgattat attatttaat
     1561 tattttatgt agatattctt aggttggtat ggaatttgta ctaacctatt aagtaatcaa
     1621 taaaactaaa taaacataga aagcacttac aaatatgtag gtgcttttta ttgaaaaaat
     1681 agaaaataaa ataaaaagta agatatagga aaaatatgta agaattatat attataataa
     1741 ttgtagcaag aagatgtaat ctacaattta tagagtggag ttcatgtatt aaaaaattat
     1801 cctcccaacg ataagaaggg aggtgaatat acatggataa ttttttattt aatgtgttag
     1861 ctagtgtaac agctagttac atagtttatt tgattagcaa gttaatcaaa aaagtaaaaa
     1921 gccactctac cgcaaagagt gacttaaaga ttgatataaa ttttaaatat catcgtaaaa
     1981 aataactttc agttatagaa cttcactcta ccgcaaatag attgtagttc ttcttgcttt
     2041 tattatacca caaattagaa aaaatattgc atataatatt ttttatagtc aataaaaata
     2101 tgaaattttt tatacacaat gatgatgaat ctaactagat gaataaattt aattgtaaat
     2161 aagaaagtac ttacttaaat ggtaggtgct tttgttttgc caaattatgc tataacattg
     2221 agtgagatga gtaatttgtg ggggaatttt acaatgtgga tattagtacc aataataaca
     2281 atagtattac ttataatagc tgtttcttct atgcaatata ttttagttat gatagctttt
     2341 ttgttgatta tatattcttt tatagaaaag aaaatagtta tggctcttgt gtcagttctt
     2401 tttttcactt attcaattta tctttgtgca acttggaaag ataaatcctt gatagcagat
     2461 aataaagttg agactgttaa ggcacaaaga gaaactgtag aaagagaaaa agaaatggaa
     2521 agaagaagaa tacaagaaga agtagacaaa gaaagatata ttgaaaaaca tggaatggaa
     2581 atatcagaaa atgatttaaa agttaagcta gaggctttag tacctcaaga atataagggg
     2641 aagaaatatg aattaaaagt agaaaaattt aaaagatata gtatgtattt tgatttaact
     2701 gtacaaaatg aaaaatttag taattctgaa gaatgtaaaa aatttgtaaa agaaattgct
     2761 aatgatctta aaaaaattaa aataagcaag gcgtacttta agtttcattc aaaagatgac
     2821 ggcggtatat ataattctgt ttatattgat tattttagaa acatacaaaa taatgtagat
     2881 aatgttgaaa atttagaatt caatgagttt gaacttaaaa ccgaagaaga agagaagcga
     2941 gaacaagaga aaatagaaca agaaaaaaac agttataata actacattca aaacagagtg
     3001 gttgacccac tagatagaat aaagaaacta aaagagttgc tagattcagg agcaattaca
     3061 caggaagaat ataataaaaa gaaaaaagaa ttattagaat agataatata gtaagcactt
     3121 acaagtatgt aggtgctttt aaatttacaa agtattccat tttaatttta tagtttagat
     3181 tttatgatat aataaaaata tagaagtttt gcagtgtgcg atatttgtta caaagtaggg
     3241 cttaatactt gaaatctaag atgttgaggg tgcgtgataa gtgttatcaa ttgcactatt
     3301 gcccgctcac tgcaatttta agagtattgt atatatgtag gtattggaaa tgctaagttt
     3361 attttggggt tttagattaa ctatatggaa tgtaaatagt tttgaagagc aaacaataga
     3421 tttttacgac tcatgtttta gattaactat atggaatgta aattaacact ctctacttgc
     3481 aaatataaat ataaactggt tttagattaa ctatatggaa tgtaaatcta tttcttctat
     3541 atcctctatt tctaagtcat tgcgttttag attaactata tggaatgtaa ataaatttta
     3601 ctctgaaaaa aattcaggtg gtgaaacaag ttttagatta actatatgga atgtaaattt
     3661 agaatcaaaa gcacttaatc ctagttcttt catagtttta gattaactat atggaatgta
     3721 aatagctttt tagcttcgtc tactacttta taagcaaagc gttttagatt aactatatgg
     3781 aatgtaaatg atgaacaata aaacaatcat ctaaagacga agaaagtttt agattaacta
     3841 tattgaatgt aaatgttcct gttgtgtttt ttactaatcc cattttatat gttttagatt
     3901 aactatatgg aatgtaaatt gctgtgattt cactaataaa acaattaata attgtgtttt
     3961 agattaacta tgtggattca aaattaaata aacaaagaaa gcacttacaa atatgtaggt
     4021 gcttttattc tgctcaaaat tggtcggttg ggtaaaatca ttagaaaaaa ttagtaaaaa
     4081 cctcttttct gtaactcgtt acaatattat tattaatgta acgagttaca gaaaagaggt
     4141 gaataaaata gcaactaaaa gtagggcaga gtatatgaaa aattgtcgaa aagataaaag
     4201 aggttttagt gtacttttag acaaagaaaa gttagataaa tttgatgaag tattagagga
     4261 aaagaatcta accaagaaag aatggctaga agaaaaaatc gacgaggaac tggaacaaaa
     4321 ggaataaaaa ataagggtca ctcccaccga ccaaagtttg agtaacccct atgatgtata
     4381 ctatcgtata tcaattataa tatatgtcat tccttaaaaa aatcaattat taaggagtgt
     4441 aatattatga aaaatgaatt aatgatgttt gaaggaaaag agattgaagt atttgaattt
     4501 gaaggaagaa ttttattcaa ctcaaaagat gtagcaaatt gtttagacat aaaaaatgtt
     4561 aatgagaata taatacttat gaatgaaaag caagttgtaa agttaagaaa ttcggatatc
     4621 agtaatactg acatccgaaa acttaataat gctggagaaa attttcttac tgaaagtgga
     4681 gtgtataaat taatctttaa atcaagaaaa gaagaagctg agagattcca agactggata
     4741 agcgatgaag ttttaccaag cataagacaa actggtgcat acataactaa taatgcaatc
     4801 ccgaaaagtt gagagaaaaa gcaagtgaga ttgaaaaatt acagttgctt ataacagtac
     4861 atctatgtta aaagaattgc tagatgatgc aggctttgac aataaatcaa aactattaac
     4921 agctaaaaca ttatataaga aagcagaaat tgatttacca atagagataa acgaagaaga
     4981 acattatttt gatacaaaac aaatagcatc taaactgaaa atatattcta agagtaataa
     5041 accagctcag atggctgttt gtgagattat taaaaagatt gatttagaag atggtgaagt
     5101 taaaggtgtt tgggaaatta atggttcttg gactggtact gtaaataaat atacaaagag
     5161 tgtaatagat aaggtgagaa cttggataga ggaaaataat agacctacca agattgcagg
     5221 tgagaagaag aattattatg tattttacaa aattgagtaa atttatcagt tgtattaaat
     5281 aatttagttt agttttgggg ggattaatac aatgtgtgag aatttacttg ataatatgta
     5341 tattgaaaag agaaaagaag aatatagaat taaacttttg aaaataagag aaacagatat
     5401 agatatatat aataagttag aaagtatagt atataaactt tctgagaaaa aattagagaa
     5461 aaataataaa tagacatata aagcacttgg atattctact gtttcaagtg cttgtttggt
     5521 ataaaatggt ataatggaga tagagaatta tattaaccaa aaaatggaga aaatagagaa
     5581 gatgatttag ttgacgcttt atcagtagga gtacctgtag gtaagacaga atctctagta
     5641 cgattagttg gagatggaat aagtgatact caaaaaagtt taataaataa aagagaattt
     5701 agaaatataa ctcaaattgg tggaaatgga aatgagaaag catttagtga agtagaaaac
     5761 ttagttaaat agattagaag gtagcaacta gagttggttg ttaccttctt tttttatact
     5821 ttctctctct aagtatttta tttttcatat cttctaatac atctaatgca gtagtataaa
     5881 attgtatatt atttctataa ggtatagcta ttggaagaat gcccttgtta actaaaaaaa
     5941 taagaagtac aataaataaa agtgtcataa tcattctaat aaaataatta gtgatatctg
     6001 ataaatcaaa tgttaagtta attgttgtag aaaatacaac agccataata gatatataca
     6061 aagcaaaaat ggggttacta tttttttgta actgtccttt aagcctagat tgctctattt
     6121 ctatatcttg aatacttttt atggaatcca tttcactata atacttataa acttttaaat
     6181 aatatttttt atacttgttt aaagcttctt cattatcttt aaggtctttg tcacttaact
     6241 ctgatttaac ttccccaaaa tccataaaat ccctcctaca atgttatata atatacttta
     6301 atttatagca tatttaagaa cttatatcag caatttgtcg aacgatttta gctaaaaata
     6361 gagtataatg ataggcttat tatttataag atattatttt ttatatagtt atatatttct
     6421 ttctaattag ataatataat gctgttgtta taatggctac taatattatt gctattattg
     6481 taatatctaa tcttcttgta aataagccta ttgctatata ctcaagacct gttacatagc
     6541 gataaagtac ttctagttta acagtttttt tcttatctat atttccatat attgattcta
     6601 atttattaaa atatttttta ctacaaaaag cagttttagg tttaattaaa tatattattg
     6661 tagttcctat tataactatt attccaataa gtataagatt gatatttcca aaatccatag
     6721 cagatacctc ctattaaatt tgcttttctt aatcaaagta tatcagtaac acaagtacaa
     6781 agagtatcta aaatattaca aatattaaca ggatagataa aactatagta aaaattgtaa
     6841 taataaagcg aacgaaaatt atcatactaa aacataagac atgttataat tgtattagat
     6901 agaagattaa catacaccaa agcactcctt ataataaaga gtgcttattt ttttgaaatt
     6961 catcaatata taaactatca agaaccttat tcaacacacc ttaaaatcga tttaaatagc
     7021 tctttttgat aacataattt atatgatata ataaaaaaat agaagtgtac caccaataca
     7081 cttctatagc tataactaag cattctcttg ctgggggagt gcttttttca tttctccaaa
     7141 caacattatt tacttcatca gtaattatca aatcaatctc attatctttc aaaatctctg
     7201 ttgcagtaca aattagatta tctaagtcaa aacttcgagt tatctctagt tgtttgttat
     7261 ttacttctct ttttagtata taagttttaa aatacattta tatcacccct tgtatttact
     7321 cttttttctc taaaaatata ttgataagta aatatgcaac aaataaaaaa atctcaatga
     7381 cacatagtgt tatagctata actagaagtg attgattttt ccatgcacta taagctatga
     7441 tgaaaagaaa tgtaaaagta aataatgtat aattcataat tttaactaag atatgacttg
     7501 ttttcattgt taagtacaag tctctttcat ctgcactatc gtgtaattct tcaacaatgc
     7561 cttttcttga aaaagcatta caaaaattaa agattgctat tacaattaaa agaaatgatg
     7621 aaattaggaa tcttttatct tttaaaatgc aataaataac taaactagca caacataaca
     7681 tacaaactat aatacccact ataaaacttc gtttactctt tactttcatg ttttttatcc
     7741 tccatttctt tattttcttt taaacaacat agttcttcaa tcgttgtacc aaacacttgt
     7801 gccatacgat aggcaagcat aagagaaggg ctatattgct ctttttcaat agaaataatt
     7861 gttctgtttg atacatggac taaatcagcg agttgttgct gtgttagacc catatttgtt
     7921 cgaaattctc gtacttttgt tttcattcca taacctcttt ctatatgaag ctaacttcat
     7981 gtgaagttaa cttcataata tcctgaaatg agtaaaatgt caatctcatt agataagtat
     8041 tataaaacct aaaagaataa tatggtaaaa attggatgga attatttacc ttaattctct
     8101 tgtttgtaaa actttattga tatagaattt aacatataca taaatcggca aaggggcgcg
     8161 aattatgaaa attagtaaat taccagaagc ggaattaaaa gttatgagat atatttgtga
     8221 agctaacaag gtattaactt ctagggaatt agttgctgca atggaagaaa aatatgagtg
     8281 gaatgaatca actacattta cagttttgaa aaggttagag cgaagggagt ttttaagtac
     8341 agagaaaata ggcaaactta cacattataa tatactagta aaagagaaaa aatatctaag
     8401 gtttgaaaca aaggaatttt tgaagaacat acataaaaat tcaatttcaa gtttaatgtc
     8461 agcgttacat ggtgaagacg acgaagtgga tgaagataaa ttaagtgaac tcgaa
//
LOCUS       DAEPUT010000130         8334 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.134, whole genome shotgun sequence.
ACCESSION   DAEPUT010000130 DAEPUT010000000
VERSION     DAEPUT010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8334
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.134"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(192..716)
                     /locus_tag="KRL22_003600"
     CDS             complement(192..716)
                     /locus_tag="KRL22_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1274028.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(781..1533)
                     /locus_tag="KRL22_003601"
     CDS             complement(781..1533)
                     /locus_tag="KRL22_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH1274029.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1564..2862)
                     /locus_tag="KRL22_003602"
     CDS             complement(1564..2862)
                     /locus_tag="KRL22_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HBH1274030.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2879..5143)
                     /locus_tag="KRL22_003603"
     CDS             complement(2879..5143)
                     /locus_tag="KRL22_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HBH1274031.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5398..6216)
                     /locus_tag="KRL22_003604"
     CDS             complement(5398..6216)
                     /locus_tag="KRL22_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH1274032.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6209..6907)
                     /gene="cbiQ"
                     /locus_tag="KRL22_003605"
     CDS             complement(6209..6907)
                     /gene="cbiQ"
                     /locus_tag="KRL22_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HBH1274033.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6910..7194)
                     /locus_tag="KRL22_003606"
     CDS             complement(6910..7194)
                     /locus_tag="KRL22_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1274034.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7184..7936)
                     /locus_tag="KRL22_003607"
     CDS             complement(7184..7936)
                     /locus_tag="KRL22_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HBH1274035.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8118..8310)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
BASE COUNT         2619 a         1514 c          898 g         3303 t
ORIGIN      
        1 aataaaattt ttttaataaa actttatttt ttagttaaaa tcatacaata tatagatttc
       61 cacaatacaa ataaattaaa aagtgaaatg tatttgtcta aaaacataat aacatttcac
      121 tttatcctca tttttaagta atatatattt ttaattttta tttataacta aatctagttt
      181 ttatataaat tttagttttt ttctacatct gagtaatcta ttccaaaagt ttctacagta
      241 acagatttca taacttgtgg agtttgtggc ttatcagctg aatctgttct aactgatgct
      301 atttcatcaa ctgtatccat accttctatc actctaccaa aacctgcata ctgaccatct
      361 aagtgtggtg agtttttatg cattatgaaa aattgagaac cagctgaatt aggtgccata
      421 gttctagcca ttgatatgac tcctctttca tgttttaaat tgttagtaaa tccattacca
      481 ctaaattcac cttttattga gtgacctgga ccacccattc ctgtaccatt tgggcatcct
      541 ccttgtatca taaatcctgg tattactcta tgaaatatta ttccattgta atatccttca
      601 tttactaatg atacaaagtt tttaactgta tttggagcta tatttggata taactcaatt
      661 ttgatttctt ttccattttc catttctata gttactatag gatttttatt ttccataatt
      721 tattaccttc cttttcatta gttaaattac ataattacat ttattatatt atactctaaa
      781 ttaaagtcta tcaagtatat tttttcctat ttcatatcct tcttgataaa tagttttaca
      841 aaactcatca tcaaagttaa gcgtgtcttt aggagcaaat tgagtattag gtctaactac
      901 tattatttta tcttcatcat atactttttt aatatcttct ggcaactcat aattatattt
      961 tgtggatatt aaaataattt tatccacatt atccccaatt aatggttcaa ttaatgcact
     1021 cctaattaaa cctccatcta atttgaaacc atcataaatt ccttcttgca catctttcac
     1081 aaattgttct ttaaatccaa gagttgcgtt tggatttgat ggtaacaacc cactgtatga
     1141 aatgctgata atggcttcat tacgaggcat ttttgatacg tcaacaatct tttctgatac
     1201 tactttatta tcaacttcaa cataattaac ataaaagttc atttcttcta tattactatc
     1261 atctagttcc cttaggttgt ctatagcagg agaattatcc acagtattat ttactatttt
     1321 tacatttcca ttctggatat cttttatatt tgtccacatt ttctccaagt tatcaacatt
     1381 ccctgtgtac aaataatatc catttattgc tcctattgat gtccctgaaa tcgaataaaa
     1441 tttatttatt cctccatcat acaaggcttt aactactcct gcttgataag ccccttttgc
     1501 tcctccacct tctaaacata atcctaattt catagtctca tctccaaatt gtttatctta
     1561 tatttatatt tcaaaaaact tactaaatgt tttatatata ctatagtggt cctcaacatt
     1621 tcctaattct cttatagaat gcattgctaa aattggactt cccacatcca cagatggtat
     1681 atctatatga gtagaagata ttggacctat agtacttcct cctctttcat ctgacctatt
     1741 aacaaattct tgatactcaa cattagcttc tctacatata tttttataaa tagctataga
     1801 atatccatca ctagtatatg cctgactagc atttatcttt ataaccggac cttttcccat
     1861 tattggttta ttagttgggt catgcttttc tggaatgttt ggatgaatag catgagctaa
     1921 atctgatgat atcataaaag atgaataaat agactcaaag aatccctctc tatccttacc
     1981 cattgatatg caaattctct ccaatatatt taacaacatg tttgaatctg caccttgttt
     2041 agtagagcta ccaacttctt cattgtcaaa tacagccatt acatttacac catgttgacc
     2101 tttagtatta acaagagcat tcaaactagc atgtaccatt gcaagattat cttgtctccc
     2161 aatagatata aattcatcat tagcccctat taaacttcct ttttcaaatt catataaaaa
     2221 taaatcaaaa tctataatat cttccatatt tacatctaag ttagatgcta tttgctttat
     2281 aagaaaatta tctttttcta atgtatcatt taacatccca actaaaggta acatatcttt
     2341 ttgcttatta tatgaatgac catcatttat acttctattt aaatgtattg ctagatttgg
     2401 tattatacaa attggctttt taaagtctat aagcctttca tttggtttta atatactatc
     2461 accttttaaa actactctac cagctatccc aagaggtcta tccaaccatg tacttaatat
     2521 tgctcctcca tagcattctg tatttaactt caaataagat ttttcagctt ctatttctgc
     2581 atttggttta atactaaatg taggagaatc tgaatgagag cctattattc taaatccatc
     2641 tctttctata tcttctgaat ttactacaaa agctactata gctgataaat tcttagtaac
     2701 ataatacttt ccaccaactc ttagattcca tctttgattc aaaactaatt cttcaaatcc
     2761 atttttatct aagatttcct tagtactctc gactgcatga aaagacgacg gactatcata
     2821 tatgaagtct attaagtttt tagcaaagtt tatactatcc attcctcatt tacctccatt
     2881 ataaaatatt tagtgttgta tattctttat ttattttttt aattccctgt tggtcaaaag
     2941 ctatagtaac atctgtacca attatagaaa ccactgtccc aaccccaaat ttaggatgat
     3001 gtaccttaga accaagtttt atatcatctg gattagtttc tttattagaa tcttttattg
     3061 tagcattaac tttatctgca actttagatt tgcttatagt actcatatac tttttagtat
     3121 atttatctaa catattataa cttgctttag aatagcttag ttcttttttt actttgtaca
     3181 atctttctat acattcttct ggcagttctt ccataaatct tgaagctatt gcaacatttg
     3241 ttttaccata taatgttctc ttctctgtca atgacatata tagctcttct ttagctctag
     3301 ttataccaac ataacaaagt cttctctctt cttctatttg tgaatcactc atagatttta
     3361 tagctcttga tataggaaat aacccttctt ccatacctgt taaaaacaca acagggaact
     3421 ctaaaccttt ggatgtatga attgtcataa gcgaaaccct atcattgtct tcttcatcat
     3481 ttgattcaga tgtaagtgct atacttgtta ggaatgtctc taagtcttta ttttcataag
     3541 tatcatcatt actactttca aactccaaag ctatagaaat aaattctctc aaattatcaa
     3601 ttctgtcttg agcttcttca cctttgcctg ttaaatcttt ttcattttta tttcttatct
     3661 ctacaagctc gtccatatat cctgtagtat ccaagacttt ttctataagt ttgctaacag
     3721 gataaacttc ttttatagtt ctaagagtcc ctataatatc aacaaatcca cttatacttg
     3781 cccttgcctt agtagatata tctgaatttg tttctatatc aattaatact gagtatatac
     3841 tttcctgttt taagttagct ctatcttcaa ttttttctat agttctaagc cctatacctc
     3901 ttctaggaac atttataatc ctttttatag atatatcatc ttgtggattt tgaataactc
     3961 ttaagtacgc caacaaatcc tttatttctt ttctctcata gaattttgta ccaccatata
     4021 tattgtatgg aatttgactt ctatttaaag cgtcctctac aggtcttgcc tgtgcatttg
     4081 ctctataaag tactgcaaaa tccttataag gtctattttc ttttctagct atttgtgcaa
     4141 ttgaatcagc aatgaaatca gcctcttcta tttcgctacc agttaattgt atctttataa
     4201 gttctccttc ttttttttca ctccaaagct tttttctttt tctttctata ttattagata
     4261 tgactttatt agctgcatct aatatcactt gtgtagacct ataattttgt tctaacttta
     4321 caacatgtac attgtcataa tctttctcaa attcaagtat gtttcttata tctgcacctc
     4381 tccatccata aatactttgg tcatcatctc caacaacaca aatattttga tgttctcttg
     4441 ctaataattt tatcaattca tattgagctt tacttgtatc ttggtactca tctaccatta
     4501 tgtatctaaa tctacttctg taatatgcta acacttcatc attagccttg aaaagttcta
     4561 cagttttaag tattaaatca tcaaagtcaa gtgcactatt tctttttaaa cggtcttgat
     4621 atagcgcata aatatctgca atcttaacca ttctattatc tgccatattg atatctttaa
     4681 actgctttgg agtataaagt ttgtcttttg ctcctgaaat tgcacttata actgcttttg
     4741 gttcaaacac tttatcactt aaatttaatt cttttagaca gtctttaacc aatgtaactt
     4801 ggtctgctga atcataaatt acaaaacttc tattgtaacc aatcttattt atatcttttc
     4861 ttagtatacg aacacagcaa gaatggaatg tacttatcca catatcctta gtttcaggac
     4921 ctatattttg ttcaactctc tctctcattt catttgcagc tttgtttgta aatgttatag
     4981 ccaatatatt tggtgcttgt acacctttat cttctataag atatgctatt cttgttgtta
     5041 ataccttagt tttacctgaa ccagcaccag ccagtataag tactggacct tcagtctttt
     5101 ctactgcttc tctttgagca ggatttaatg tatctaaatt catatttctc ctcctgttaa
     5161 cagccataaa tatattttaa tctaaaatat gaattacttc aaattataat tatgtattat
     5221 attaatagat tatttccaat atattacaat taaataacat ttttccatat aatttatttc
     5281 attgtttaat aaaaaaaata accttatgat ttggggaatc ataaggcacc tttaaggggt
     5341 ctaggttaag ggttattata tataaatcta tttttttaaa ataggtttag ggcttaatta
     5401 tttatttgta ttaagttctc tttccttcca atacttatac aaatcttctt ctttcttaaa
     5461 taagggtaaa ttcatatttc tatgtacttt tactaaccat ggggattcta gaccagcttg
     5521 tataatatta ttttcattta taaacacatt ttctgccttt ccttcatcaa tcaaaatccc
     5581 cttatccaat acatatatgt aatcacatat ttcatacatt aaattcatat catgactgga
     5641 tattactatt tttatattat ttttatttaa tccctttatt atatctacaa tagacctagt
     5701 acttactggg tctaaaccag ctgtaggttc atcaagtaat acaatttcat tttccattgc
     5761 tataactgat gctattgcca ctcttttttt ctgtccatag ctaagaaaat gtactggcct
     5821 gtctataaaa tctattccat taacagctac tagagctttg tttattctct ctttaattgt
     5881 tttttcatcc ataccaatgt ttctcattgc aaaggctata tcatcatata cttttgaata
     5941 aaaaatttgt ttttctgggt cttggaacac aatacctaca ttttttctaa ggttgtataa
     6001 acttctctta tcatatttta acttttcttc tttaaaaaga atttctccag atgtaggctt
     6061 taatataccc attaaattca taaataatgt tgattttcct gaaccatttg aacctattat
     6121 acctataaca tttccctttg aaaaatccat attaatgttt aatagtgcat tggtattttt
     6181 ttcatattga tacgttaaat tatttatttt aaacatcatt atcccctact atgtgaaatt
     6241 taccatcata caattttatg tctaatgata tacacatatc atcatacctt gtcataagtc
     6301 ttttgtacag catacttcca agaataccta aggatttata tgaagttttt aaatttatat
     6361 atccaaatct tagctcttgt gacttgtata tttctgaaaa ttcttctaaa aatatgaata
     6421 taaacctata tattaacatt gataactcga caaaagtgtc aggtaaatga agttttttaa
     6481 aaaagaatat taattgatta aaaggtgttg taagtataca aaaatacaca caagtcaaac
     6541 aagacatcgc tctaaataac acatgaatag acatgtcaat agacgccttt gatattccta
     6601 cattaaaact aaaaaattca aaactatata ataaatctgc tttattaaaa gatatattta
     6661 caagagttat tcctatacta agaaataaaa agtacattgg tattctaagt aattttaaat
     6721 aattttttaa atctattcca gccacacaaa caaccaaaat actcattaaa atcataattc
     6781 cacttaaaat aaatatattt tgtattacca tagaagcaat cagaaaaatt actcctatgg
     6841 ctactttttt gtttggattt actttactca atctatttgt atatgcatat ttatcaatta
     6901 taagcatgat taacttctct ttcctttttg aagacctaat atgtatccta ttacaccagc
     6961 ccctaaagct gcttgtgcag agaataataa actttctatt tctccacttg gtggctcata
     7021 tggactgcta aaccatggtt tgtaatttgg atttatctta gtaatttcac tttcagcttg
     7081 accatctgct cctccatatt cagcacctga gttgacaagt aatgggaata taataagagc
     7141 tactactaat aaaagtaata atatgttagt ttttgttttt gttttagcac tcattagctt
     7201 taactccttt atcattattt tctagtatgc ttttttctcc gttttctgta attaaattat
     7261 atacaattac agtaagtata ccttctgcta ttgctattgg tatttgagtc ataaagaaaa
     7321 ttcctaaaaa tttaattgct gaagccatta ccccacctga tgggtctgga aaagccagtg
     7381 ctaattgtat tgaagttatt gtatatgtgg ctaagtctcc tattgctgct gcaagaaata
     7441 ctggaatagc attatttcca tcttttttct ttaaagcctt aaatattagg aatgatacga
     7501 ttggccctat tatcgccatt gaaaaagcat tagctcctaa agtagttatt cctccatgtg
     7561 ctaataacaa tgcttggaat attaaaacta tagttccaag aacaaacatt acgcttggtc
     7621 caaacattat tgctccaaga cctacaccag taggatgtga acaacttcct gttactgaag
     7681 gtatttttag tgctgataat acaaacacaa atgctccaca taaagctaat aatactttct
     7741 ttttagggtc ttgctttact attttaccta ttgattttaa tccgaataag aaaaatggta
     7801 taaatataac tccccatgct atagaccatt ttactggtaa gtaaccttcc attatatgca
     7861 ttgcatttga tgtaactgga gttaaaatga ttaacataag tgcagctata acccctaatt
     7921 taatattctg tttcatctta gtatccctct ctccctttct aataattaaa acataataat
     7981 acatgtctga tttatttaat aaaataaaaa agcctaactc gatggttagg cttctaattt
     8041 tccacaatct aaatacaaac acataaaaca aacatatctg tataattatt ataagaaact
     8101 ttctccatcc ccgaagaaat tactttaata ttttaggcag gtctcctgac ttagcttcat
     8161 cctactcctt ttccttccca tgagatataa aaaatatcat catagtggct aacaaaagtt
     8221 tcgtctgcat cacagtagcg ggggctgtaa aggaatttaa cctttttccc tattaatctt
     8281 gcttaaagaa cctataatat tatatattta atttttaaat tattcttaaa ttat
//
LOCUS       DAEPUT010000131         7995 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.135, whole genome shotgun sequence.
ACCESSION   DAEPUT010000131 DAEPUT010000000
VERSION     DAEPUT010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7995
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.135"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            439..1740
                     /locus_tag="KRL22_003608"
     CDS             439..1740
                     /locus_tag="KRL22_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1274036.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1816..2091
                     /locus_tag="KRL22_003609"
     CDS             1816..2091
                     /locus_tag="KRL22_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1274037.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            3589..3819
                     /locus_tag="KRL22_003610"
     CDS             3589..3819
                     /locus_tag="KRL22_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1274038.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            3812..4393
                     /locus_tag="KRL22_003611"
     CDS             3812..4393
                     /locus_tag="KRL22_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1274039.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(4972..5649)
                     /locus_tag="KRL22_003612"
     CDS             complement(4972..5649)
                     /locus_tag="KRL22_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1274040.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(5838..7202)
                     /locus_tag="KRL22_003613"
     CDS             complement(5838..7202)
                     /locus_tag="KRL22_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1274041.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYVARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINEFCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            7330..7851
                     /locus_tag="KRL22_003614"
     CDS             7330..7851
                     /locus_tag="KRL22_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH1274042.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPETAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         3128 a          892 c         1379 g         2596 t
ORIGIN      
        1 tatattaata attggcagta aattatatta aataagatat tactatagag taatgaatta
       61 tagtgaacga tatatcaata attggcagta agttatatca aataagatat tactatcaag
      121 tagtgaatta tattgaacga tatattaata attggcagta agttatatca aataagatat
      181 tactatcaag taatgaatta tattgaacaa tatattaata attggcagta agttatatca
      241 aataagatat tgctattatg tagtaaatta tataaaacaa tgtatcagaa taaatagtat
      301 attaataatt tgtagtatat catgacgaat aatacagtca taacaaatag tgagtcataa
      361 caaataatgt atttataatt gataatgtat ttaaaaatca aaatataaaa acttataagg
      421 aaagagagat taatttatat gggtaaatca aaagatgttg aaatagagaa gtctatttta
      481 ggcacaattc ttttagacaa taaattaagc tataagctag atgaattaaa tgaaaacatg
      541 tttatgaatg atatatgtct tgagatattt aaaattatga aagaacttaa aaaagaaaac
      601 atagtgattg atgtggccac tgtgaaatca aagatagata gaaaatctct agcaataaaa
      661 acaagtgatg tgactaatct aattacttgg ggtcagaatt ttggtcttga tggtcatatt
      721 aaaattttaa aagaaaattt agctagaaga agcataaatc aaaattgcca aaacctttta
      781 cacagcctaa accttggaga aaatatcgat acttgtattt acaaatttga aagtaatata
      841 aaggagattt tggacaagga tacttatgaa aatgatgatg taaatagtat agcagggaag
      901 gtgcttgatt ttttagaaaa caaaaaagat attggattta aatttggtat aaaattactt
      961 gataccacta taggaggtct ttttaaagga gagctaacca caatagcagc taaatcgggg
     1021 gttgggaaaa ctgctttggc acttcaaata atgttaaatt catttaagca aggtaaaaaa
     1081 actttattta taagtagaga aatgaccagt gagcaagtat ttatgagaaa tatatgcaga
     1141 gtaactggtg taagtacaag gaatatgaaa tctaaagaaa tagatgaaaa tgattggaaa
     1201 cttattgtaa atgctatagg tgatttaagc gaaaataact taatttatat taatgataag
     1261 atagatacaa ttagtgcaat tagaaagagg ataaggcagg taaagccaga tttattaata
     1321 gtagattatg tgcaactcct tacatctcag aaaagcatgg ataagagaga aagggaagta
     1381 gctacttttt cgagagaact taaaaatatg actttagatt ttaatatacc tgtaatccaa
     1441 ttaagtcagt taaatgatga aatgaaagat tcaagacctt atggagatag acctatgagg
     1501 gatagcaaag ccatctacca cgatagcaac aatgtggttt atatacatca attaaagggg
     1561 agtgattatg aagaagcagt gagagatatt ggagaaagtg aggaggcagt tagagcatca
     1621 gaatacaggg gaattaagat ggttgattta atagttgcga agtgtagaga tggacagact
     1681 aggcataagc atttttgtta ctttggggat aagttacatt ttcaagaact aaattattag
     1741 gtcaataaag tagtaataac aagcttatta aaagtcggga aatagcaaat agattataaa
     1801 atatgaggtg aaaatatgtt ggaattaaga aaaattatag aattacttga agaacacaag
     1861 atagaagtaa gtattccaaa ggagttacat aagtatagtt tattggaata ccttgaattg
     1921 tgtcaacaaa gtgggggaac atatttttat attaaaacac tggaaggggc tttaaaagag
     1981 gctagaaatg agcttatgat taaattgttt aatgggaaaa attatatgga attagcgagg
     2041 atgtttgaaa tgagtgttat taatgtcagg catattgtta gaaaaaaata gatatttttg
     2101 gagaatacaa gtgtgatata cttctgaaat agaagttatt atagttgaaa taaaattgtg
     2161 gttaataaat taaagttgtg tataagttta agattataga ggagtataag tgtgattaac
     2221 aacatgattt tgtgaataaa attgaggata tatatgagtt aaatgtgtga ttaataaggt
     2281 aaggttgtgt ataagattat gagtatttaa aaggaggggc tataattaat agtgtagagt
     2341 tgtgtgtttg cttaagatta tataataatt taatagatta aactatacta ataaggtaaa
     2401 atcgtgtgtt tagttaaagc ttattataaa atcttgatat gtgattaatg atgcaatatg
     2461 tgaataaagt taagattata atagatttaa cctgtggcta atagaataaa attgtgaata
     2521 aagttaagat tataataggt ttaatctgtg actaatagag taagagtgta aatagagata
     2581 aacttcaata tgagcttaac ctatgattaa tagagtaaga gtgtaaatag agataaactt
     2641 caatatgagc ttaacctatg attaatagag taagagtgta aatagagata aacttcaatg
     2701 tgggtttaac ttgtggttaa tagagtaagg tgtaactaaa gataaacttc aatatgagtt
     2761 taacttgtga ttaatagagt aaggtgcaac taaagataaa cttcaatatg agcttaactt
     2821 gtgattaata gagtaagaat gtaaatagag ataaacttca atatgggctt aacttgtggt
     2881 taatagagta agagtgtaac taaagataaa cttcaatatg ggtttaactt gtggttaata
     2941 gagtaagaat gtaaatagag ataaacttca atatgagctt aacttgtgat taatagagta
     3001 agagtgtaaa tagagataaa cttcaatatg ggcttaactt gtgattaata gagtaagagt
     3061 gtaactaaag ataaacttca atatgagctt aacctatgat taatagagta agaatgtaaa
     3121 tagagataaa cttcaatatg agtttaactt gtggctaata gagtaagagt gtaaatagag
     3181 ataaacttca atatgggttt aacctgtggt taatagagta gggtgtaact aaagataaac
     3241 ttcaatatga gtttaacttg tggctaatag aataagattg tgaataaagt tatagtttta
     3301 gatgggtatt aacctgttac taatagaata tgattaggtg taaaattata gagctgtata
     3361 agaaaatatt atagatatat taaatattag ataataaata tttatataga tacacaaaag
     3421 aaaaggcgat atgaagctaa acttaatgac ttcatatcgt tttttatttg aaactccttt
     3481 gtatttagag tgtgattttt aatattgagg ttttatgtga ttaagtcaca gataaaaagt
     3541 aagtatcttg atataattct tatagattaa taatataggg aggttattat gtctaataaa
     3601 aaaaagaagt atgcaaatat tttagcaaat gagtgcgttg cttgtggtag ctgtataaaa
     3661 gcatgtccaa gaagtgctat ctcagttcca tgtggcatta gtgcaaaaat taatagagat
     3721 ttatgtgttg gatgtgggat ttgtgaaaag atatgtccag catctgtaat tgagattata
     3781 acaatattaa aagaggaaga aggtaagtgt catgaataat aaaaaacatt ggtatgacta
     3841 tttatggatt ttttcttcaa tatatttgat attgggattt gtaaatatta ttttcgcttg
     3901 gattgggcta atttgtttct ttgttccact agctatttct attgttaagg gaaataaagc
     3961 ttactgtaat aagtattgtg gaagagggca actgtttaat ttgcttggaa ataaattgaa
     4021 gctgtcaaga aatagagata ttcctaaatt tattagaagt aagtggttta gatatgggtt
     4081 tttgacattt tttatggtaa tgtttgccaa tatgcttttt tcaacttatt tagtgtttga
     4141 aggaagtaga aattttaaag aagtagtgac tttgttgtgg actataaaaa tgccttggca
     4201 atgggcgtat catggaactt tagtttcacc ttgggtggta cagtttgcat ttggttttta
     4261 tagtgttatg cttacatcaa ctgttcttgg tttgattact atgatattgt ttaaacctcg
     4321 ttcatggtgt gtttattgcc ctatgggtac tatgactcag atgatatgta aggcaaagag
     4381 taagtctgta tagaaaggcc ttatgtgata tttacagttt tgttcaagta gagatgagta
     4441 gtaggtttga atatatatga caaatatatg agtatagggg catagattta gtttgtgtaa
     4501 ggtaaactga tttatgcttc ttttttatgt cttagattat tggctaagtg gaaacaatga
     4561 atttagatat taagaattat tcagttattt gaagaaaata gaataataat taacattata
     4621 ttaatggata ttcattacat ataagccagt taatagcaag atttatttaa tatgaaatag
     4681 gtcaagtatt taaactaaat aaggtcatga caattaatat aagtatagat ataaaaagat
     4741 tagaagttat aacttataaa aggtattcta tataaatagt atggggaaaa tagtcaaatt
     4801 aacttattag aaacaaaaaa tatacataaa aaataaatgt aaatatcaaa taagatacta
     4861 tatcaaaata gatataagta tcttttttat tattgaaatt atgaaaatat atttgatttc
     4921 acacaaaaaa gagtgcctca tgaactaaaa agttcatttt gagacacact tttacagtgt
     4981 caaagaacga agtttatcct tatccaatac ttttatacca ccacgagata aagacacaat
     5041 accttctcta gcaaaatatt tcaacattct cgatacaact tctctggcac tacccatata
     5101 cttagcaatt tgctcatgag tcatatttat agtgctactg ccatttttag ctatctcatc
     5161 aattaaaaaa gatgccaaac gcttatcaaa actcataaaa agaatttgtt gcatagccca
     5221 cataacatca gaaaaacgtt cggtagctaa tttatatgaa aataactctg catgaatatt
     5281 ttctgtagat aattttgcaa aaacagagga actaatctgt ataatatcgc agtccgtttc
     5341 agcatctaca tagacatcaa aagttattgt ttttagaata caggaagctg ataaaataca
     5401 tacatctcca tcatcaagtc ggaacagtgt aacctctcga ccttcatctg aaagtatgta
     5461 tgtacgcact gttccagact ttataatcaa aatgccaata cagtcactat caccacaatg
     5521 tactggattc ccttttttgt aatgtgaggt atttgctgaa gaaattaata attctttttg
     5581 taagtcagta agtttatccc aaaaaggcaa gctatgtgta agtatatcga tttcattttg
     5641 tgaaatcata caatatctcc tttcttaaat tgttataatc ccatgataca agtgaataga
     5701 taaattgaca agtagtttgt taataggatt atttagtcag atagtaatag tatgatttat
     5761 gtagaaaaaa tatgataata tgtattcttg ctattaatga gaaagtaata tgttttgatg
     5821 atagtaggtt tgtataacta atgcataccg tttattttta aaagattaag ttccttatgt
     5881 aaccttatag acataaaacc agcaattata gcagccatca aatcagctat tggttgtgca
     5941 tataagatac catttaaccc atagaataca ggaataatca aaattatagg gataaaacag
     6001 acaccttgtc tacacatacc taaaaatcca ccttcctttg cttttcctag tgcgaggaat
     6061 aatgtagaat acactgtata gaatccaaat agcataaatg aaaacccatt tgccctaaga
     6121 gctttactac cattttctat taataaaatg tcaccacttg taaattgtga aattatagat
     6181 tttgggaaga gtatcaatat aagaccaagc actacacaaa atactgtagt ccataatatg
     6241 gaagttttta ttgctatatg taatctatcg tagttctttg aaccaaaatt ataaccagca
     6301 attggttgga aaccttttat aaaaccaaat acaacaagac tacctaaaga cgttattcgt
     6361 gttacagcac ccattccagc tatcacagaa tcaccatact ttgtagcctc catattagtt
     6421 aatgtaatgg caagactagt caataattga aatattaagg taggtatgcc aatttttagg
     6481 atttctgaaa aaatttcttt tgaaaaacag aattcgttaa ttctaaaact aaatatactt
     6541 ttcttgctta aaatatatcc tacataaaca agtgttgaag caatctgtga gatagctgtt
     6601 gcaatagaag caccccttac ccccagacca aaagtataaa tgaatatcgg gtctaaaatc
     6661 atattaagca aagcacctaa taacatagca cacatagttg ttttagcagc tccttcactt
     6721 gtgacaatat tagtcatagt gacattgaat atattaaaaa tagatgacac gacataaatg
     6781 ctagcataag atattgcata aggcataata ctttttgtag ctcctaataa ttttaaaatt
     6841 ggattgagaa aaatcataat cacaataata actaatgtac ccactataat actactgtaa
     6901 atagatgtac ttaccacttt tcctgctttt tcattatcac catggcctaa aagtctggca
     6961 acatatgaag cagctccatt tccaaacaat aatcctaatc ccacaacaag ctgacctaat
     7021 ggaaatgcaa cggatatagc tcccatttga cttgttccaa gtccacccac aaagtatgca
     7081 tcaaccaaat tgtataatgc agttatcatc atacctatca tggtaggtaa tcccatagat
     7141 aacaatgctt ttgagattgg ggcagaccct aataattcaa ttcttttgtt actttctttc
     7201 atgcttaaca ctcctcttct attgacatta agtctaaatt ataatactat aaattatagt
     7261 aagtatggaa aatagtacta taatttatag tatttgtcaa tagtaagaaa actaaaggag
     7321 atgattttta tggctacaat agatttaatt gtattgggaa tagtaaagca acaacccaag
     7381 agtgcttatg atattcaaaa ggcagtggaa tacaggaata tatcacgttg ggttaaaata
     7441 agtacaccat caatttataa aaaagtaatt caattagaac aaaagggata tattgaaagt
     7501 aaaactgtga agaatggaaa aatgccagaa aaagcagttt attcattaac tgaattaggt
     7561 gagacacatt ttttagattt aatgtttgat acatctagca aaccaataaa tattctttta
     7621 gattttaatg ctgttatagt aaatttaaat agccttacac cagaaaaaca gaaattatgt
     7681 ctcaataata ttgaagagaa tgttcaagag ttaaagaaaa ctattgagga aaatataagt
     7741 ataaagacag aagtaccaga gacagcaaaa gcagtgttgg agcaacagtt ggtgctagca
     7801 caagcattgg aaacctggat aaattcttta aaagataata tgggaaatta gaattagaga
     7861 agctaactta ataatcatta aacaaaaacc agcatattta ataatgagat attagaaaaa
     7921 ataaaacaaa tgatataaac tgaaaagtat atttaaaata aagctcactt aattgaggga
     7981 gaatgttaaa ctttt
//
LOCUS       DAEPUT010000132         7975 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.136, whole genome shotgun sequence.
ACCESSION   DAEPUT010000132 DAEPUT010000000
VERSION     DAEPUT010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7975
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.136"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            68..529
                     /locus_tag="KRL22_003615"
     CDS             68..529
                     /locus_tag="KRL22_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1274043.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            597..2843
                     /locus_tag="KRL22_003616"
     CDS             597..2843
                     /locus_tag="KRL22_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1274044.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRFSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            2836..4668
                     /locus_tag="KRL22_003617"
     CDS             2836..4668
                     /locus_tag="KRL22_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1274045.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            5387..6664
                     /gene="hflX"
                     /locus_tag="KRL22_003618"
     CDS             5387..6664
                     /gene="hflX"
                     /locus_tag="KRL22_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH1274046.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            6897..7394
                     /locus_tag="KRL22_003619"
     CDS             6897..7394
                     /locus_tag="KRL22_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1274047.1"
                     /translation="MDAETLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIEIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            7444..7968
                     /locus_tag="KRL22_003620"
     CDS             7444..7968
                     /locus_tag="KRL22_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH1274048.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILNYIREL"
BASE COUNT         3156 a          825 c         1464 g         2530 t
ORIGIN      
        1 aaatgcatgc agtatagtaa aataatactt agctgactaa gtaatataaa aaataaggag
       61 ggcaagtatg aatagcaatt ctgaagaaaa attaaatgat gttttcttgc aattaatgcg
      121 aatatatttt ataagaactc atttttattt tgataaatta ggcttatatc atggtcaacc
      181 ccaaatactt ttttctttaa agatgaaaga tgggcaaagt caaaaagaat tagcagataa
      241 aaggaaagta aaagcatcta caactacagt tatgataaag aggatggaaa aagctggact
      301 tgtggaaaga aaacaagatg aaaaggacca aagagtatct aggatttttt tgacagacaa
      361 aggtttagaa atatgtaata aagttgaaga atttaacaag gaattggaaa gagagttttt
      421 tttaggattt agtgaagaag aaaaaatagt acttagaaga cttctaatgc aagtacgaga
      481 taatttaaaa gcaggatgtc ataagcatga agatgaaaaa tatttttaaa gtttaaaata
      541 atgtttttca atttaatgtt attagactaa ttaatattac agaagggaag aaatgtatgt
      601 ttaaattaat taaatattta aagaaatcgg cattatcaat agtaataata gtctgtctat
      661 tggtaattca agcggtatgt gacctttctt taccagaata cacatccaat atagtaaatg
      721 taggtataca acaaggtgga gtagaaaact ctgttccatc tgtgattaga gagagtgaat
      781 taaataaaat tactttattt atggataaaa gtagtaagga taaagtacta gataattata
      841 ctttgctgaa taaaaaggat tatgttaagt ataaagataa gtacccaggt ctaaaagatg
      901 aatctcttta tgagttaaat actaaagaca aagacactat agatgattta aatgttattt
      961 ttggtaaagc tattttaata gtatcagggc ttgagggcga tagtaaagag gtaaaagcta
     1021 tgaaagctca gttaatgagt aaacttccac cacaagctac tcaaagtgga gatgttgata
     1081 tatttaaatt gttatcagca atgccaaagg aacagttaga tacattgact aaagagatga
     1141 gcaaaggctt tgaaagtatg ccagagagta tgataacaca aagctctgtt tcatatgtaa
     1201 ggtcagaata tgagaaaata ggtattgata cagaaaaaac tcaaaataat tatatattat
     1261 ttactggtgc taaaatgctt ggtatagcaa tgattagtat ggtagctaca ataacagtag
     1321 gatttttagc agcaagagta gccgcaagtg taggtagaaa tttaagaagt ggagtattta
     1381 gaaaagttat gtcattttca aatactgaaa tgaatgaatt ttctacagct tcattaatta
     1441 ctcgtagtac aaatgatatt caacagatac aaatgttgat ggttatgttg cttagaatag
     1501 tattctatgc acctataatg gctataggtg gagtgataaa ggttttaaac acaaatactt
     1561 caatggcctg gattatagca gtagcagtag ttgctatctt atcattaatt gtagtgttat
     1621 tctcagtggt tatgcctaag tttaaactgg ttcaaaagct tgttgataag ttaaacttag
     1681 taagccgtga aataattact ggtattccag ttatcagagc ttttagtact gaaaaacatg
     1741 aagaagaaag atttgataaa gcaaataaaa atttaactaa aacaaatctt tttgtaaata
     1801 gagttatgac atgtatgatg cctgctatga tgcttataat gaaccttatc acagttctta
     1861 tagtttggag aggtgcatac agtgttgatt ctggagcaat gcaagttgga gatatgatgg
     1921 catttataca atatacaatg caaataataa tgtcattctt aatgatatca atggtatcta
     1981 ttatgcttcc aagagcatcc gtttcagcta cacgtataga tgaagtatta gtgtcagata
     2041 taagcataaa agacccagaa aaatcagagg cacaagagtt taaggaagat aaaaagggtc
     2101 ttgttgaatt taaaaatgtt tcgttcatgt atccagacgc agaagaacct atattaacaa
     2161 atatatcttt tacagcaaag ccaggagaaa caactgcctt tataggaagt actggtagtg
     2221 gtaagtcaac tcttataaat ttaattcctc gtttctttga tgttactgaa ggagaaatat
     2281 tacttggtgg agttaatata aaaaatgttt ctcaacatga tttaagggaa aaaattggat
     2341 atgtacctca aaagggagta ttgttttctg gtactataga atccaactta aaatatggta
     2401 gaaaagacgc aacagatgaa gaaatgagaa cagcagctga aatagctcaa gctacagaat
     2461 ttatagattc taaaccggaa gcttttaaaa ctgaaatttc tcaaggtgga acaaatgtat
     2521 ctggaggtca aaaacaaaga ttttctattg caagagcaat agcaaaaaat ccagaagttt
     2581 atatatttga tgatagtttt tcagcacttg acttaaaaac tgatgcagct cttcgtaagg
     2641 ctttaaaatc aaaaactgct gaaagtacag ttctaatagt tgcacaaaga attagtacta
     2701 tcttaaatgc agaacagata attgttttaa atgagggcga aatagttgga ataggaacac
     2761 ataaagagct tctaaaaaat tgcgaagttt atgagcaaat agctttatca caactttcaa
     2821 aggaggagct agctaatgag tagaatggga agaggtccta tgggaaaatc tatgggagca
     2881 ggacaaaaag caaatgactt taaagggact atgcgaaaac taattgcata tttatctaaa
     2941 tttaaaatat caataatttt agtaattgta tttgctattg gtagtgcgtc gttttctata
     3001 gtaggtccaa aaattttagg aaaggcaact acaaagatat ttgaagggct agtgagtaaa
     3061 gtttctggag gaaacgtagg tatagatttt aatgcaattg gaaaaatctt aaccttttta
     3121 cttttccttt atttgataag tgcactgttc tcttttatac aaggatttat aatgagtgga
     3181 atttctcaaa aagtatccta taatttaaga aaagagattt cagcaaaatt ggatagatta
     3241 ccaatgaagt attttgatac taagacgcat ggtgaaatat tatcgagaat tacgaatgat
     3301 atagatactt taaatcaaag tttaaatcaa agtatgacac agcttataac atcagtaaca
     3361 actatgatag gtgttttgat aatgatgtta tctataagtg gaattatgac attagtggca
     3421 gttttaatat taccaatatc aatgtttgta atttcaagaa taataaagaa atcacaaaaa
     3481 tactttagat atcaacaaga atatttagga aatgtaaatg gtcaagttga ggaaacttac
     3541 agtggccaaa caatagtaaa agcatttaat cgtgaggatg aagtaattga agagtttgat
     3601 aaactaaatg atagcctgta taattcagcg tggaaatctc aatttttatc aggtataatg
     3661 caaccactta tgatgtttat tggaaacttg ggatatgtaa tggtatcaat cttaggaggt
     3721 tggcttgcaa ttaagaaaac aattgaggtt ggtgacatac agtcatttat acagtatgta
     3781 agaaacttta cacagccaat gactcagatt gcacaggttg ccaatttatt gcaatcaaca
     3841 gcagcagctt ctgaaagagt atttgagttt ttagaagagg aagaagaagt ccaaattgtt
     3901 gaaaatgcag tttcaataga tggtttagaa ggtaaaattg attttgaaaa tgtcaacttt
     3961 ggatataacc caaacaagac tataataaat gatttctcag taaatgttaa acctggtcaa
     4021 aaagttgcta ttgttggacc tacaggagca ggtaaaacta caatagttaa actgttaatg
     4081 agattttatg atgttaatag cggttcaata ctgattgatg gtcataatat taaagatttt
     4141 aatcgtagtg agcttagaga aatgtttggt atggttcttc aagatacatg gttatttagt
     4201 ggttcaatta tggaaaatat aagatatggt aagttgaatg ctacagatga agaagttata
     4261 gaggctgcta aatctgcaca tgttcataga tttattaaga cattaccaga tggatataag
     4321 atgaaattaa atgaagaagc aagtaatgtt tctcaaggtc aaaaacaatt attgactata
     4381 gctcgtgcta ttttagctga tcctaaaatt ttaatattag atgaagctac aagttctgtc
     4441 gatactagaa cagaagtatt gattcaaaaa gctatggata atcttatgga aggtagaaca
     4501 agttttgtta tagcccacag attatcaact atacgtgatg ctgatatgat tcttgtaatg
     4561 aatgaaggag atatagttga acaaggaaat catgaggaac ttctaaagaa aggcggattc
     4621 tatgccaatc tttacaattc tcaatttgaa gaagatgaag caatgtaaca aaaaactatc
     4681 ttagtataga catgtaatta ataagataaa ataaatgagg gtgccttaaa atgaactttt
     4741 tagttcataa ggcactcttt tgtgtatgaa ataaagtgta tttttatcat tttaacaatg
     4801 aaaaagagga ttctctatat tttgagatag ccacataatt ttatgtcttt acaaagtgtt
     4861 tattttatta taatatgtag taaggaaaat gttggaggtg attatcaaaa tgtatattta
     4921 attttattct ttaaatttta ttataaatag aatttaattt taatagttga tgattatatt
     4981 gaagtatatg tttttattac ttttattaat catgcaaata actacttaaa tttaagaata
     5041 gggttaaata taaaatgata attacatata agttaattaa actaatgtat ttttaatata
     5101 tatttagaat tttaatcctt cttatgatat aagtagcttg ttttgtatta cttagatttg
     5161 taaggagttt ttttattgaa aaaactgcat aatatatttg ggaggaggtg taagaaagtg
     5221 attttttata taagattgag aaaataatgc acgattatgg ttattataat agtaaataag
     5281 aagtgtcatt taaggataag ataaaaagca aaattcttga tgaatttaat tatagagcca
     5341 taatctcgtg ctatagatta aataaaaaat agcagataag gagaatatgg atatggcgaa
     5401 aaaaggaata acagtaggat taaacataaa taataaatct gaggacttta atgaactaat
     5461 gattgaactt gaaaacttat gttcagcatg tgatattgat gttgtaggga gtataactca
     5521 aaatgcaaag caggttaata gagcatttta cattgggaca ggtaaagttg aggaaatatt
     5581 aaacttaata aagaaagaaa atatagagat agttatattt tacaatgaac tttctacatc
     5641 acaactaaaa aatcttgaag aaaagcttaa ttgtgaaatt atagatagaa cggcattgat
     5701 acttgatata tttgcacaaa gggcaaaaac tagagaagct aaacttcaag tagaagtagc
     5761 aagtttaaaa tatatgttac caagacttat aggttcaaat gaaaatttag gacgtcaaag
     5821 tggtggagtt ggtactaaaa atagaggttc tggtgagaaa aaattagaac ttgaccgtag
     5881 aagaatagaa gaaaagataa catctttaaa tagggagttg gatgatttaa aattccaaag
     5941 agaaactcaa agaagtatga gaagaaaatc aaatcttcca aatgtagctc tagtcgggta
     6001 tacaaatgct ggtaaatctt caataatgaa taaactagta gatatattta aaaactctga
     6061 agaaaagaaa gtgtttgaga aaaacatgtt atttgctaca cttgaaactt ctgtcagaaa
     6121 tatagttctt gcaaataaca aagaattttt attatctgat actgttggtt ttgtaagtaa
     6181 tctaccacat gacttagtaa aagcatttag gtcaacatta gaagaagcat gtgaggcaga
     6241 cgtactgtta catgttattg atatttcaaa tccaagctat aaaagtcata ttaaagtgac
     6301 agaagatact ttaaaacaaa taggtgcaga tggtatacct atgatacatg tgtataataa
     6361 aattgatcta atagatgtag aagtattgga tagaatttta gatagtatcg ataaagaagg
     6421 tatatttgtt tcagttaaaa aagatataaa tatagataaa atgataaaat gtatttgtga
     6481 tagcatattt aaagattatg taagatgtaa gttcttaatt ccatatgata aaggtcatgt
     6541 agtttcttat tttaacgaaa atacgagcat tataaataca gaatacagag aagatggagc
     6601 tattttagat gtagaatgta gcaatataga atataataag tataaaaagt atgctttaga
     6661 gtaaattttg aaaaacttat tatagcctaa aatatattta atttataatt tattataaat
     6721 tgattgtaaa tatgatttta tgaaacggta tagccataat gctatgccgt tttgccattt
     6781 ataataaaaa taaatttatt gacacaatag taactaatta ctataatata aagtaactag
     6841 ttactattta aaattatcaa aaaattaaaa tctaagataa agagaagtgt ataataatgg
     6901 atgcagaaac tttaatgaaa aaatatatgg tagatgatga tagtagaaaa caagctatat
     6961 ttgcaagtat atttgtaatg caaaataaac ttcaaactac atgtgataaa ttagacccag
     7021 aattaacaat gaaacaatgg ttacttttag ctattgcgga ctctgtagat gaaactctta
     7081 cattaaccaa acttggagaa ttaatggggt gttcaagaca aaatgtaaaa aaactagcta
     7141 ttgctttaga aaagaaaggt tttatagaaa ttgagcaaaa tgaaaaagat tcaagagcta
     7201 tctgtcttgt gacaaaagat agagtgcaag agtattctaa aaaagtaaga ggtatgcagg
     7261 aaaaagtatt acagctttta tttgaagatt ttacagagaa agaagtggaa cagttatttt
     7321 ttggaattat gaaattaagt ataggaattg aaaatgtgaa aaattatgta gaaaataatg
     7381 acgttggaga ataagcaagt atcaaatcaa ctttgtatga catcagagag ggggggaatt
     7441 tatatgaaaa atgtagtagt gatttataag agtaagtatg gttcaacaaa aaaatatgct
     7501 aaatggcttt cagaattatt gtcttgtgat atttttgaaa ctaagaatat taatatagaa
     7561 aaggttatga agtatgatac gattatttta ggaggaggtc tttatgcttg taatatagcg
     7621 ggaatttctt tcttaaaaaa aaattataaa gaattgcaga aaaaaaattt agtagtattt
     7681 ggcgtaggag ctgctccata tgatgatgaa gtaataaaga aattaagaga agtaaatttt
     7741 aaggatgaat taaacaaaat tccttgcttt tattgtcgtg gggcatggga tgagacaaaa
     7801 atgtctttta tagattatac tctttgtagt ttttttaaaa aatctatagc taaaaaagaa
     7861 cgtcaaggtc ttaaaccagc agaagcacct ttattgtctg gagaagcatt tgattggtgt
     7921 aataaagaaa atttaactcc aatacttaat tatataagag aactttaaga ggtat
//
LOCUS       DAEPUT010000133         7798 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.137, whole genome shotgun sequence.
ACCESSION   DAEPUT010000133 DAEPUT010000000
VERSION     DAEPUT010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7798
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.137"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            139..1197
                     /locus_tag="KRL22_003621"
     CDS             139..1197
                     /locus_tag="KRL22_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HBH1274049.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            1301..2485
                     /locus_tag="KRL22_003622"
     CDS             1301..2485
                     /locus_tag="KRL22_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1274050.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            2692..3405
                     /gene="rpsB"
                     /locus_tag="KRL22_003623"
     CDS             2692..3405
                     /gene="rpsB"
                     /locus_tag="KRL22_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBH1274051.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            3484..4395
                     /locus_tag="KRL22_003624"
     CDS             3484..4395
                     /locus_tag="KRL22_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBH1274052.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            4480..5184
                     /locus_tag="KRL22_003625"
     CDS             4480..5184
                     /locus_tag="KRL22_003625"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBH1274053.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            5210..5767
                     /gene="frr"
                     /locus_tag="KRL22_003626"
     CDS             5210..5767
                     /gene="frr"
                     /locus_tag="KRL22_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBH1274054.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            5770..5973
                     /locus_tag="KRL22_003627"
     CDS             5770..5973
                     /locus_tag="KRL22_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274055.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            6002..6736
                     /locus_tag="KRL22_003628"
     CDS             6002..6736
                     /locus_tag="KRL22_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBH1274056.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            6749..7528
                     /locus_tag="KRL22_003629"
     CDS             6749..7528
                     /locus_tag="KRL22_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBH1274057.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         3216 a          795 c         1465 g         2322 t
ORIGIN      
        1 aagcacaatg aagtagatta aaaatttaaa actaagaatc taatatatat tttgtaacta
       61 tttaagtata taaaataaaa taatatccaa actaatacaa aatagtaata attgttttgt
      121 actggaggat atatatttat gaattgtaaa tggatatcta aaatagatga gagaaaaaaa
      181 tgtcatagag aagcagattc ttctggatat tgtatctttc ataaagaaaa taagtctgat
      241 gaagagatac aattgatgat ggatactctt cataaagaag agataagtga atttaatgga
      301 tttgtttttg aaaatgaatt taatgcggaa gaaatattaa cttacaatta taaaatactg
      361 gatttttctg aatccatatt taaacaaaaa gcaaatttta aaaaatatat ttttaaaaag
      421 aatattattt ttaactatac agaatttaga gataaagttt tatttaatgg ttgtgtattc
      481 ttagaaaact gtgattttaa tagaaccata tttagtaaac actatataaa tgaccgtata
      541 tttgaaaaag tgaaatttaa aggacctgat ttggtagtta ataaagtaga aaattttcca
      601 cgaatggatg gaataatttt tagcatgtgt acaaaatttg tgttaaagaa tgttgaatat
      661 ggaaaaagtg agtatgagca tggcaagata aattatagaa tagctagaaa tcaagcaaca
      721 aaaattggag aatatgagat gataggattt tactattata aggaaagaat ttatagtagt
      781 aaaataatga aacgttctaa ttatcctact ttcagtgatt atttagttga aaaatttttt
      841 gaccaaatag cacgttacac aacaggttat ggagaaaagc catggaatat attattagtt
      901 attatagcaa taataagtgt ttttgcttta ttatacttat ttgtaggcat agaaagttca
      961 aatagcacac ttgtagcttt agatataaac aatataggtg attactcact aagtgagatt
     1021 ttcaaaatgt atatggattt atggtatttt agcatggcta catttagtac agtaggatat
     1081 ggagatatgg ttgctacaag tttgattggg aaagcattgg caggtataga agtatttttt
     1141 ggagttacaa taggagcaat ttgggcatct gtgattatta aaagaatgat aaggtaatat
     1201 ttgtgtaaat atggataggt attaattact agatataaat tggactaaat agggaaaatt
     1261 taaatataaa tatacttaat aatccaagaa ggtgaaaaat ttgaaaaatg cactaaaaaa
     1321 aattatatca ttagccatga ttctagtttt tataatacca aattattcat atgcagatga
     1381 taaatctgta gacaagtatt caaaaacatc tatacttata gaccaagaaa caggtagagt
     1441 tttatatagt aaagaacctg atatgaaggt accattagct agtttaagta agatgatgac
     1501 ttttttactt gcaatagaag ctattgaaaa taaagaagta aaagaaactg ataaagtaaa
     1561 aatagacaaa tctattgcat cagtaaaagg gtcaagttat aaacttaaag atggtgaaga
     1621 agtgccactt atagagctta tgagaggtct tatgattgta tcaggaaatg atgcggcaat
     1681 tgctatagca aaacatattt gtaaaacgaa agaagcattt gtagatagaa tgaataaaaa
     1741 agcaaaagaa ataggaatga gtaatacaca ttttctaaat ccaaatggtc ttccaatata
     1801 cgatttaagc aaccccaaaa aaccagcaaa agaaaatatc tctactgcaa aagatatagc
     1861 tattcttgga aaatacatgt ttgaccatta tgaaaaacaa gtaacagcta taactgatat
     1921 ggagacatat acaaattcag atagaagttt tgaaaaaagc aatacaaatg cattattaag
     1981 aattatacca gaagtagatg gtataaaaac tggatatact ggcaatgctg gatattgctt
     2041 atcattttct atggttgtaa ataaaaatga taaaaatgag aaaaaacgta gagtaatagg
     2101 ggttgtatta ggtactaacc ataaaaataa aagaacctct gcttcattag ctctactgaa
     2161 atatggaaaa gaaaatttca atatgaaaaa agtaattgat aaagatagct ttattggtaa
     2221 gaaatatata aaaggaatga aagagttaga ggttacatta aaagcaaaag atgaacttta
     2281 tacaatatta aaagatgatg aaagtataaa atcagaagtt aagattaaaa atatagagta
     2341 ccctgttaaa aaaggtgata ctatgggtat tataaaatat tatactaatt caggtgactt
     2401 acttggaagt gtagatatag taagtaataa tagtatagat aacgtatcat taaaaacaaa
     2461 attaaaaatg aaatttgcaa attaaattca aaaaatggta taaaatacac aaaaaaatat
     2521 aaaaatagaa aatatggaaa aaatattgtt atttcttcac ctctgtgata tactactaga
     2581 ggtgaaaaaa taaaataaat cacacacagc attgggatcc ttaaaaggtg cctattacat
     2641 ggttttttag ggagaagatc aagctggagg tataaaacca ggaggtaaga tatgtcagta
     2701 atatcaatga aacaattatt agaagcaggt gttcactttg gtcaccaaac aagaagatgg
     2761 aaccctaaaa tggctaagta tatattcaca gagagaaatg gaatatatat aatcgactta
     2821 caaaaaacag ttaaaaaagt tgaagaagct tacaagttca ctaaagaagt agctgaaaca
     2881 ggaaagccaa tcttattcgt aggaactaaa aaacaagctc aagatgcgat aaaagatgaa
     2941 gctgaaagat gtggaatgta ctttgttaat gaaagatggt taggtggaat gttaacaaac
     3001 cacaaaacta taaaaacaag aataaataaa ttaagagaat tagaaaaaat ggaagaagaa
     3061 ggcgtattta atgttcttcc taaaaaagaa gttataaaat taagagctga aaaagaaaaa
     3121 ctagaaaaat acttaggtgg aataaaagac atgcctgaat taccaggtgc aatgttcgta
     3181 gttgacccaa gaaaagaaaa catagctatt caagaagctc atagattagg tataccagta
     3241 gttggtatag ttgatactaa ctgtgaccca gaacaattag actttgctat accaggaaat
     3301 gatgacgcta taagagccgt aaaattaata actggtgcta tggcaacagc tgtaattgaa
     3361 ggtagacaag gtgctgagga agaagtagct gaagaccaag aataataatt tgacaattaa
     3421 atggtaaggg tcgcccttac catttataat atggaataga ataagtagga ggaaacttaa
     3481 aaaatggcta atataactgc tcaaatggta aaagagttaa gagaaagtac aggcgcagga
     3541 atgatggact gcaagaaagc tttacaagaa gctgaaggaa acatggaaaa agcagtagat
     3601 ttattaagag aaaaaggatt atcaaaagct gctaaaaaag ctggtagagt tgctgctgaa
     3661 ggtctagttg caatagaaat gaatgatgat aatacagttg cttctatggt agaagttaac
     3721 tcagagacag atttcgttgc taaaaacgaa gacttcaaag tgttcgttaa agatgctgct
     3781 tgtatggcat tagctactga taaagaagat atagcttctt tattaggtga aactcataaa
     3841 gagggaataa ctttacaaga agttttaaat aatagagttg caaaaatagg tgagaaatta
     3901 gactttagaa gatttgctaa agttgtaact aatggacaag ttgctggata cattcacggt
     3961 ggtggaaaaa taggtgttct tgttgaaatg gaaacagaag ctagagatgc taaagtttta
     4021 gaattaggta aagatgtagc tatgcaagtt gctgctatga atcctaagta tgtttcaaga
     4081 gatgaagtag atgctgaata catagcacat gaaacagaag tattaactca acaagcttta
     4141 aatgaaggaa aaccagctaa tatagttgaa aaaatggtta aaggaagatt agaaaaagaa
     4201 ttaaaagagg tttgtttatt agagcaaact ttcgttaaaa atccagatat aactgttaaa
     4261 caattagttg ctgatgttgc taaggcagta ggttctgata taaaagttgt taaagttgtg
     4321 agattcgaag ttggtgaagg tatacaaaag agagaagaaa actttgcaga agaagttgct
     4381 aagcaactta agtaataacc aaagagagaa cacgcaggtg ttctcttttt taaaaaatag
     4441 aaaaaattgg atatgaagga ttgaaatagg aggtttctga tggataaacc aatgtacaaa
     4501 agggtattgt taaaattaag tggagaagca ttagcaggag aaagaggttt tggtataaat
     4561 aatgatgtag ttaatgatat tgctattgct ataaaaaaaa tacaagaaat aggtgttgaa
     4621 gtagctgtag tagtaggtgg aggaaacttc tggagaggca gaaccagtga aggaatggac
     4681 agaactactg ctgactatat aggaatgtta gctacagtta tgaatgcaat ggcgctacag
     4741 gatgcactag aaaatataga tgttgctaca agagttcaaa ctgctataga catgagacaa
     4801 attgcagaac catatataag aagaagagca gttagacact tagaaaagga aagagttgtt
     4861 atatttggtg caggaacagg aaacccttac tttacaacag atacaactgc tgctttacgt
     4921 gctgctgaga tggaagcaga agttatattg ttagctaaaa atgttgatgc agtatatgac
     4981 aaggatccaa aagtacatgc agatgctaag aaatttacag aattaagtta catggaagtt
     5041 atacagaaag aattaaaagt aatggattct acagctacat ctttatgtat ggataataaa
     5101 attccaataa aggtatttga gcttacaaca gagaatataa taagagcagt aaaaggcgaa
     5161 aatataggaa ctactgtaaa ataatgaaga atgaaggagg agtaaaatta tgaaactgga
     5221 aatacataag caattagaag agaaaatgaa tgggacaatt gatgctttaa agtttgaatt
     5281 tggaactata agagcaggaa gagctaatgc acaaatgcta gacaaaataa gagttgatta
     5341 ttatggaact ccaactccaa taaatcaaat aggtgctata tctgtaccag aaccaagaat
     5401 attaatgata tctccttggg ataaatctgc tatgcatgaa atagaaaaag caatagctaa
     5461 ctcagactta ggattaaatc catcaaatga tggtgaggtt ataagacttt ctgtacctgc
     5521 tttaacagaa gaaagaagaa aagaattagc taaaaaagct agtaaagctg cagaagaatt
     5581 taaagttaga ataagaaatg aaagaagaga cgccaatgag aagattaaaa agatggaaaa
     5641 aggcggagaa ttaactgaag atgaattaaa aaaagcacaa gatgaagttc aaaaaatgac
     5701 tgataaattt ataaaagaaa tagatacatt attatctaaa aaagaaaagg atataatgga
     5761 ggtataatat tgaaaaaata ttataacctt ttaggtcttc atgtagatga ggtaaaacaa
     5821 tattttgatg agcaaaatat aaattatacc gtaaaatcta ttgaaggtaa aaaggataaa
     5881 gaaaaacttg tagttcctag agttataaaa atatctgaga taggtgatag tgtagaactg
     5941 ataatcacat acttttctga ctccttagtt taaggagtca gaacaatatt ggaggcaaaa
     6001 tatgaataac aacattatat atgatataga cttaaataac atacctactc atattgctat
     6061 tataatggat ggaaatggaa gatgggcaaa agctagattt cttccaagaa ctgcaggaca
     6121 taaggctgga gtagaaacta taagagatat agtaaaagaa tgctcaaaat taggtgttaa
     6181 gcacttaaca ttatatgcat tttcaacaga aaactggaaa agaccgaaac ttgaagttga
     6241 cacacttatg aacttattat ctacatactt aagaaatgaa atagctgaac ttcaccaaaa
     6301 caatgtaaaa gtaactgcta taggagatat aagtgcttta ccaaaaactt gtataagaga
     6361 attaaactca gctaaggaac tgacaaaaaa caatacagga gttaacttaa atttagcatt
     6421 aaactacgga agtagagcag atataaaaaa tgctcttata gatatagtaa aaaattgtga
     6481 aagtggtaaa atagatataa acaatattga tgaagatatt ataaaaaact atttaagcac
     6541 aaagtctata ccagatccag acttggtaat aagaacaagt ggtgaacaaa gattgagtaa
     6601 ctttttactt tgggaagttg cttattctga gttttacttt actgatatac attggcctga
     6661 ttttaaaaaa gaagaactac agaaggctat atacgtatat caaagaaggg atagaagatt
     6721 tggaggactt aagtaaggag attattttat gcttacaaga attattgctt cactagctct
     6781 ggttccatta tttctatttg ttgtatatgg aggtattcct ctatatatag ctgagacagc
     6841 aatagtttat attgcattgc atgagtttta taaggcattt aaaataaaag atgtacatcc
     6901 aatattcatt ataggatatt tattttctat ttatttagct gtaaaaaata tttttaattt
     6961 accattagaa tatacttatg cagtaatttt tattttattt ttagcaagta taatttatat
     7021 gttgatgggc aaaaacaatg ttatagatgt ttcgattacg tttttaggag ttttttatat
     7081 aggagtattt ttagatttta taattataac tataaatgga tttgaaaaag gtagtatata
     7141 tgtatggctt atatttgtga tatcttttat gacagatata tttgcatatt ttagtggtta
     7201 tttacttgga aaacataagc taattcctaa agttagtcct aaaaagacta tagaaggagc
     7261 tattggagga ataataggaa gtacactttg ttgtatttta tttggatatt tatttggcat
     7321 tgatttgctt caattagcga taataggaag tataggaagt gtaatagctc aattaggaga
     7381 tttatttgca tcttctataa agagatatgt agggataaag gattatggaa agataatacc
     7441 tggtcatggg ggtatattag atagatttga tagtgttata ttagttgcac cttttgtata
     7501 tagtgcgatt aaatttttta ttagataaag attggttgga tttaaaagag caatctataa
     7561 ttgctagtaa tgaaaatagc tatgtaactt ttaaatgcag agatattctg cagttattag
     7621 ttacatggct attttcattg ttcaaaaatt tagaagacct tggggaattg tataagaata
     7681 ggtattactt tataatagta tactatattt gtagtgagta tattttttat actgtaacta
     7741 tcattaaaaa atattttttt gtttaataat ttcgatattt ttagctttat tatatatt
//
LOCUS       DAEPUT010000134         7596 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.138, whole genome shotgun sequence.
ACCESSION   DAEPUT010000134 DAEPUT010000000
VERSION     DAEPUT010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7596
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.138"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            618..1310
                     /locus_tag="KRL22_003630"
     CDS             618..1310
                     /locus_tag="KRL22_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1274058.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            1506..3566
                     /locus_tag="KRL22_003631"
     CDS             1506..3566
                     /locus_tag="KRL22_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1274059.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMVISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDIAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(3771..4094)
                     /locus_tag="KRL22_003632"
     CDS             complement(3771..4094)
                     /locus_tag="KRL22_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBH1274060.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(4087..4788)
                     /locus_tag="KRL22_003633"
     CDS             complement(4087..4788)
                     /locus_tag="KRL22_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBH1274061.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(5066..6451)
                     /locus_tag="KRL22_003634"
     CDS             complement(5066..6451)
                     /locus_tag="KRL22_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1274062.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(6559..>7596)
                     /locus_tag="KRL22_003635"
     CDS             complement(6559..>7596)
                     /locus_tag="KRL22_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH1274063.1"
                     /translation="YKHNIDNYIPYDQGITLDIFMYIWILGIIAISFYYLRTNFKFYN
                     YIENFKKEILEIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTRCKIIIPEKK
                     YNNKELRFIFKHELIHYKRKDNLFKLLISTICIIYWFNPILYLLKKYFHELCELSCDE
                     IVIDKCTTSEIKEYAYIILDTIKYQKTLKYSSFVSQFLNKKNIILKKRLDSMFNQDKK
                     KINLGLKFLLTFIIIGSIFSINSNFKQNEDVEYTIGKINYNKNGETYGTHIIDSNGNS
                     IEPELIQTIGRGKKVGYVKKRDLYDCDNQPKTPEEAVLYTRKRNFNIFKKTIPLYDKE
                     GIKIIGRFEIN"
BASE COUNT         2927 a          853 c         1071 g         2745 t
ORIGIN      
        1 aaataagaaa atgacaaatt gatacataat aaataaaatg aaggtatgaa attataactt
       61 tttctacctt cattttgttt attattctga acatgttaag aaaatgaaat aagtttgtat
      121 tttatttata taaattttaa tagaatatgt atagtatata gtagatagaa tgtataaaaa
      181 tagaatttaa ataagtagct attattgcag tgaaatgaat gtttctaagt atatttgggt
      241 ggaagaatgg tggaagaaaa ttagtgaaat gtaattcttc caccattctt ccacctagaa
      301 aatagaaact gtttaataag aattaatata cattaattca gctgaatgca atcaaaatac
      361 ttaaatgaaa gtaatctgaa aacaacataa ttcaaatcaa tttattcaaa taaacctcaa
      421 tttatcttaa atcttaagaa atatttaaga attaggataa tattttctta agatttatat
      481 tttattatat agttataagg gaaagttaca aaaatgtaag ccaaagtaat ataacaattt
      541 agtcattgtt gagaaaggga gtgaaagata ttgtataata tagataagta ttattataca
      601 atagaggaag tgaaaatatg tacaatatat tagtagtaga cgatgataaa gaaattgttg
      661 attcgataga aatatatctt aaatcagaag gatttaaaat atataaagca tatgatggaa
      721 tgaaagcttt ggaaataata acagagaatg acattcatct aatactaatg gatataatga
      781 tgcctaaatt agatggaatc aaagcaactg taaaaatacg agaagaaaga aatattccaa
      841 taattttaat ttcagcaaaa agtgaagata cagataaaat aataggatta aatattggag
      901 ctgatgatta tataacaaag ccatttaatc tattagagct tatagctagg gttaaatcaa
      961 acttaagacg atatgtaact ttaggtaatt atgaagatac atgtaaagaa attctaaaaa
     1021 gtggagcttt ggagttaaat acactaacaa aagaagttaa aattgatggt gaaaacataa
     1081 aaatgactcc aattgagtat aaaataattg aacttctttt agaaaataaa ggacgagttt
     1141 tctcaataga tgagatatac gaaaaagtat ggaatgagga aagttttaat tcagaaaata
     1201 cagtagcagt acatatcaga cgaataagag aaaagattga aataaatcca aaagaaccaa
     1261 gatttttaaa ggtggtgtgg ggagttggtt ataagattga aaaattttag tggaaaaatt
     1321 ataaaagaaa agagtttaat atttaattgc attttgattt tagtcatttt tacatttaca
     1381 caaatgttag gaattttaat atgttttaat tttttctctg agagtttaat ttactctatg
     1441 gggattatgc ttttcttaaa ctttatttta tataaaatac tgacaatgta gatgaggtgg
     1501 gcaacttgga gaaatataga gtattaaagt tagtttcatt aatcataata tctatctcat
     1561 ttccattaac tatattgttg gtgacaatag gacttgctga gcctaaatac aatatacaaa
     1621 aaacttctac aaagagtggg atttttgata tatctgatga tttttatgat agtaatatat
     1681 ttgacgaagg aacaatggca agtctattac ccaagtttaa gctatctgta ggtggtaaat
     1741 taactagtaa agaaaaaggt aaattccaac aagaaggtaa aagtatagat ttaagtagta
     1801 gtgattctga gtatgataaa atcatgatta atgaacaagc ttctgaagaa tatttaagtt
     1861 atctaaaaaa tataaaagtg tatgtcatta atacatacac aggagtattt tatacaaata
     1921 cgtcatatgc tagtttatat gattttaaac aaaaaactaa gagctattgt aatgtagaga
     1981 taataaataa gataggaaag agctcatata ttaaaacaat aaatggagaa aaatttgaac
     2041 tgaataatct gagtctggaa ctaaatgaag tagatgaagg ttttgaggca tatgtatctt
     2101 ttccagaaga gccaactata gaagatggaa tagtatatac taattttcaa atatttaaac
     2161 aagctacaga aaaagtaaga ttattttttg tagctagttt aagtttagca attatatgtt
     2221 tattatctat aattttatat atcaaaataa aaggtgaagt tttaaaaaga aataatgtat
     2281 ttttactaat atacagtaag atacctatgg aatttaatgt aatattagta tctatttcaa
     2341 ttgcaatttt aactatatat gctcttgctg tatcttatca tattgatgta attgcattag
     2401 tttctttatc tttactgata gtatcaaata atatattttt tataaatgtg caattgagtt
     2461 atttagaaaa taaaatgtgt atatttaaga caagtattat agtaagagtg attttatggt
     2521 taataaaaac tgtaagggag gtcagtaacg ctataaagaa agtatcttta gcaaggaaag
     2581 ttattgttat agtgataata tctttagctt taatcatggt aattagcact cgaagtatag
     2641 gtatgggatt actgttttct atatgtattt ttttaggatt tacaatatat ataactaaaa
     2701 gactttcata tcttagttac gtaatagaag gtacagaaag aataaaaaag ggagaattag
     2761 attataagat aaaaattact gggaatgata attttacgtc tttagctgaa aatataaata
     2821 atattggaga aggtcttgat atagctatag aagagcaagt aaaaagtgaa agaatgaagt
     2881 ctgaccttat aacaaatgta tctcatgatt tgaaaactcc acttacttct ataataaatt
     2941 atgtagattt aattaaaaaa gaagaatcaa tacaaccaga gtatataaat gattatataa
     3001 atgtacttga gtcaaagtca aaaagactaa aattattgat agaagattta tttgaagcga
     3061 gtagagtaag tagtggcaat atagaattac aaattagcaa gattgattta gtgcaactat
     3121 taagacaaag tataggtgaa cttgaagaaa aattatctaa aaataattta tatttaaaat
     3181 taaatgttcc aaatgataag gtgtatatat gggcagatgg aagaagaatg tatagagtat
     3241 ttgaaaatct tttatctaat atagcaaaat attccttaga agaaactaga gtctatattg
     3301 atgtatatga ctatggtgaa aatgtaaagg taactatgaa aaatatatct tcttatgaat
     3361 taaattttga cccaagtgag attatggaaa gatttaaaag agctgatgaa tcaaggaata
     3421 ctgaaggaag tggattaggg cttgctattg caagagattt agtagcttta caaggtggaa
     3481 aattttatat agaaatagat ggagatttat ttaaagcaaa tttagagttt caaaaatatg
     3541 aagaagaaat aacaaatatg gaatgagata gtatttaagt atatatattt ttttactgtc
     3601 gaaagctttt attataatat attagaatat ttacagtaga gaatgaagag taaaaacaga
     3661 gtaactttaa gtcactctgt tttttattta aaatcaataa tataacaact taaattaaaa
     3721 ttgtacacat agttttaaaa taacttatac aataaaacat tatccaaata tcacaagata
     3781 attccaaata aatatataga tatcactcct gtaataatag aaataccaat agatttaaac
     3841 ttatatgcaa caagaagtac aatcataaaa gatataattt tagggttagc tatagataaa
     3901 tatagactat ctccattaaa aaatacatct ttagcagtta aggaagtaag tattgctaca
     3961 ggtataaatt tcatgatttt tttcaaaaaa tcaggcatct ctttttttga aaaaattaac
     4021 ataggaagca ctcttggtag atatgtaaca atgtacattc caattataat aaaaaatata
     4081 taattattat tcataagatt cctccttttt acagtaagat tcttctataa agaaaccaat
     4141 taaagatgct aaaattgatg caactattat tactaaattg cttttgaata atgcatataa
     4201 aataacagaa ataatgattg atgatataaa tactacaata taaatcttat tttttatttg
     4261 agaaactatt aaagctataa acatagaagt caatatgaag ccagaaatag aactgtctat
     4321 agatatactt tctcctaaaa atgctccaat aaaattagct aaaactgatg aaattaagca
     4381 gaagaaatta agataaatag catttctatc agaccaattt ccagcagtaa atttttcata
     4441 attaactgca aaagtttcat ctgttatagt atgacaaaat ggcaatataa attttggact
     4501 tttatttttt atgtacatgt tcaaattaga actcattaga aaatgtctta agttaactat
     4561 aaatgtagtc aaaacaatag atgttacact tgcaccagta gaaatcattg aagctgcaat
     4621 gaattgagaa cttcctccaa atactaaagt taccattagt gctatttgaa aaggtgaaag
     4681 accagatttt tgtaatagta ttcctcctac tatacctata ggtatataac ctaagaatat
     4741 aggaattgaa gcaataaagc tttcttttaa ttgttgagtt ctttccacaa taaatcactc
     4801 cttttgtatt aaatgtatta aagtattcgt aaaacagaaa aatagattaa ttgtataatt
     4861 gcaattataa ttaaaaataa atttggatta atatataaaa tactatacaa caaatagata
     4921 atcttaaagg gttattaaat tttatctatt tgttattatg atgtaataat acatattaat
     4981 ctctataagt taattactat ctggtgtaat tttattttaa caacaaaaaa aaatacacac
     5041 aattaaaata ttgtgtgcaa tacaattatt ttttctcttc taatagtctt tttaatacgc
     5101 tcaaaccagc tttaagttct tctgtacttt ctgtagcaca tacagctatt cttattgcag
     5161 aaattggttt ttcttttcca acagcaaaac gttcagaagc atagacctgt acaccttctt
     5221 taagtgcttg tatctcaaat ttttctgcca ttattccatc aggtagaatc aaccatctaa
     5281 atatacattc ttcatttccc aaaagattat atccagataa atattgatta ataatcttgt
     5341 ttcttcttct tgcagattta cggcgtgcat taattaattt atcggcttca cctgatgtaa
     5401 tcatgcgata agcaatttct gttaaaaaat aagattgaga tagattaatg ttgtataatg
     5461 cgcttgataa tgcctctcga tactgtttag gtgtagagat atatgctagt cgtaaactag
     5521 gtgcaataat ttttgataaa ctcgtaatat aaattgtttg attgggcaga taggaagcca
     5581 ctggatttaa atgtgtttca ttaagtaaac tatgaatagc atcctcaata acaattaaat
     5641 tgtatttaga tgcaatattt gcaatcattt ttcgtccatt ttgtgacatt atatgtgtag
     5701 ttggattttg ataatctggt attatgtata gacctttaat attttcattt ttacaagcat
     5761 ataatagtcc ttcttcacta atctcattat cttcttgttt aattggaatt agttgaatcc
     5821 caagcatttt agctgctgtc tttattccag gataagttaa tgggtctaca cctattctat
     5881 ctccatgttg aaacaaacca gctaaaatag caacaattgc attttgtcca ccacttgcag
     5941 gaagtaagct atctgatgta gtttcaagcc cagctttata aattaatttg gcaatagctt
     6001 ctttttgcca tttagcacca tctctttgtc catattggaa tatggtttta aaatctattt
     6061 ccttaattat gtgtttaaac aaagtattca tttcttctag cgtgaaatct ggattcattg
     6121 tgcccatttc aataaatgta attttattat tactggacat caagaataga tttgaacgtg
     6181 tatcataaga tacaaaagtt ccacttcctg taactccact tattagacct tttttttcac
     6241 aaattttaaa agctctagag atagtactca cattaacatc taagaaatct gccaattcac
     6301 gttggggtgg taatttagta cctggtaata aaaatccatt gttgatatct tgttctagtt
     6361 gttctgcaag agccttatat aatatttgcc cttttgaagg tctctttggt ttccagttca
     6421 taggataatt ttcaaaagaa ttaattggca taagttttca cctcacatta ttaatttgat
     6481 tttttcttta tctaaaacaa taaattctaa agatacaaat aaaaactgat aggaaataat
     6541 tctatcagtt tttgtctttt aattgatttc aaatcttcct ataattttta taccttcttt
     6601 atcataaaga gggattgttt ttttaaatat attaaaattt ctttttcttg tatataaaac
     6661 agcttcttct ggtgtctttg gttgattatc acaatcgtac aaatctcttt tttttacgta
     6721 gccgactttt ttacctctac ctattgtttg tataagttct ggttcaatgg aatttccatt
     6781 tgagtctatt atatgtgtac cataggtttc tccattttta ttataattaa tcttaccaat
     6841 agtatattct acatcttcat tttgtttaaa attggagttg atagaaaata ttgaccctat
     6901 tattataaag gttaataaaa acttaagacc taaattaatt ttctttttat cttgattaaa
     6961 catagaatct aacctctttt ttaaaataat atttttttta tttagaaact gagatacgaa
     7021 tgatgaatac ttcaaagttt tttgatactt tattgtatct aatattatat atgcatactc
     7081 tttaatttca ctcgtggtac acttgtcaat cacaatttca tcacaagata attcacataa
     7141 ttcatgaaaa tattttttta ataagtataa aattggattg aaccaatata tgatacaaat
     7201 tgtactaatt agaagcttaa ataagttatc ttttctttta taatgaatta attcatgttt
     7261 aaagatgaat cttaactctt tattattgta ctttttttct ggaattatta ttttacagcg
     7321 tgttaaacct ataatggcag gagaataaat acctttaacc ttatatattt gaagtttttt
     7381 atttatactt agttcttttg cttgttcatc taagatacta gtaatatcta tttctaaaat
     7441 ttctttttta aaattttcta tgtaattata aaatttaaaa tttgttctta aatagtaaaa
     7501 agagattgct ataattccta atatccagat gtacataaat atatctaaag taatgccctg
     7561 gtcatatggt atataattat cgatattatg tttata
//
LOCUS       DAEPUT010000135         7367 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.139, whole genome shotgun sequence.
ACCESSION   DAEPUT010000135 DAEPUT010000000
VERSION     DAEPUT010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7367
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.139"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            117..767
                     /locus_tag="KRL22_003636"
     CDS             117..767
                     /locus_tag="KRL22_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HBH1274064.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(907..2283)
                     /locus_tag="KRL22_003637"
     CDS             complement(907..2283)
                     /locus_tag="KRL22_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1274065.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2299..4212)
                     /locus_tag="KRL22_003638"
     CDS             complement(2299..4212)
                     /locus_tag="KRL22_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1274066.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4348..4980
                     /locus_tag="KRL22_003639"
     CDS             4348..4980
                     /locus_tag="KRL22_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBH1274067.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5119..5658
                     /locus_tag="KRL22_003640"
     CDS             5119..5658
                     /locus_tag="KRL22_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH1274068.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAKKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FEMDREGYKRYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFDKYERFYEEY"
     gene            complement(5834..6004)
                     /locus_tag="KRL22_003641"
     CDS             complement(5834..6004)
                     /locus_tag="KRL22_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1274069.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            6289..7356
                     /locus_tag="KRL22_003642"
     CDS             6289..7356
                     /locus_tag="KRL22_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HBH1274070.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
BASE COUNT         2802 a          968 c         1059 g         2538 t
ORIGIN      
        1 agaatgaatt tgtcaagttt aatttagttg taattttatc ttttattaaa aataatataa
       61 attaaaacat ataaataaaa tattttatac aatatattgt aaaggaggta actttgatga
      121 aagcagaaaa aacaagtata tatccaatta ttaaaaataa tttaaacaaa atatcaattg
      181 ttgaatataa aaagggtcaa agatttgtag catcagataa agacttacaa gaagtgttct
      241 ttataataga gggagttgca ttagtggagt gtactactag aggaggaaat aaatttcttg
      301 ttgacattgt acctgaaaat gaatttatag gcaaaattag ttacatatat gaacataatt
      361 tgaaatgtga tatatttgca aagactaata taaaattatt tcgatttgaa aaaaatgtat
      421 ttgaagagtt ttatctcaaa ccagatttta ttgcactatt tcacagaaaa tgtacaagaa
      481 gaatatatga attatataaa accagaatgg taagagaact attttcttgc acagaagtta
      541 ttgcctattg tatatcaaat aaacaagaaa ataatgtctg caatataaaa gctattcgta
      601 atttcagtga aatctattca attagtagaa aaagtagata ccattctctg ctaaagttaa
      661 ctgaaaagga gatagtaaaa aaaatgggta atacatatga aattttaaac tatgatgaat
      721 tacataaatt ggcatttgaa gtaaaagaat ttttggaaga tgagtaaaaa ttgttactta
      781 atcaaaataa agtataataa tttctgtaaa aaatagaaat agtctcactg aaaatcaaaa
      841 atactttagt tattttcaat gagactgttt agaaatattg tatacttata atgtatagta
      901 taattattaa tcaatttcct ttactatatt aatagcccat tttttagata atgctctagg
      961 aacaccaaat ataaacttaa ccacttcttc actataagtg agcaaaacga gtacaaatat
     1021 aggtgcacct ttaaatgcag ctataaaagt tagaggaata gaagctaacc acatacatcc
     1081 taattctaaa aatagagcat atttagtatc tcctccactt cttaaaatac caattataac
     1141 caatgtatta aaagatttaa gagccattag tattcccatt ataaagaata tcttagttat
     1201 atcagaagct aagctatcag aaacactaaa catttttaat aataatggta tatttaaaat
     1261 taaaataatt ccaagtatta aaccagctga aaatacaagt atagaaaact ttttagcata
     1321 ttcaatggct cttttaatat ggtcagctcc aagttcattt ccaagcataa tagatgcacc
     1381 agatgcaata catacagctg tcattatgaa gaaattacct gtactggttg ctatctggct
     1441 agctgctata gcagaagtac cagctcttgc atatgcaaca gaatacagga cagttccaat
     1501 tgcccataca gagtcattta caaatatagg aaagcttttt gatgaaaaag attttataaa
     1561 aattttatca atagctttta gattttttag accaaacttt aatatatagt cttttttata
     1621 aaggtaaaca taagtaatca ttaaaattaa ttcacatatt ctagcaataa cagtagctag
     1681 agcagcacct tttacaccca atgcaggaag accgaagtta ccaaatataa atccataatt
     1741 taaaataaca tttgttacaa gtgcaaatgc actacaaatc atacctaact taggatttct
     1801 aacacctctt gaaccagtac taaatacagt acttacagca attaatggat aactaaatac
     1861 tgcaatacta aagtaatcta tacaaagttt taccacctca gaatcatacg aaaatatgtg
     1921 tataattggc tttggtgtta gtaaagcagg aataacaaat acaaaactta aaacaattgc
     1981 caatacacaa gtaagacctg tgacttttct tatattactc acatccttct ttccataaaa
     2041 ctgtgaaata aaaactccag cacctcctgt gataccagat aaggacatat taaaaagaaa
     2101 gaaaaattgg tttgcaactc caactgaagc tacagatgtt tcccccaaac tacttatcat
     2161 aattgtatct attacattta cagaagtaga aattaagttc tgtatgataa taggtataca
     2221 taaagataga agtattttat aaaatctttt attttcgtct tttaaagaaa atagttcttg
     2281 caaataatcc tctccttttt acataaattc ttcccactca tcatatagag aggcaaggtt
     2341 attttctaaa ttaatttttt cttggctaac ttctttagct ttatctggat tagagtatac
     2401 ttcttcttga cataaaagta tatctaattt ttcaatttca atctctaact tttcaatttc
     2461 tttttctata ttttgtcttt ttattctatt tttcttttct atttctcttt gttctctctc
     2521 ttttcttttt tcatctttta tttgagttct agttttttct tctttttctt ctataatact
     2581 catctcttgg atttgccttt ttttatctat ataataatca taatttccca gatattcagt
     2641 aattccattt tcatctaaaa ctaaaatttt atcaacaaca gtatttagaa agtatctatc
     2701 atgtgatatt gtaaatatag tcccatcata attagttaag gcctcttcaa ggacttcctt
     2761 agaatcaata tctaggtgat tagtaggctc atctaataac aataagtttg catttgatag
     2821 tataagttta agtatggcaa ctctagctct ttctccacca ctcaatgtag aaatcttctt
     2881 aaaaacttct tcatctacaa ataaaaatgc ccctaacata tttctcaaag tagtttgagt
     2941 aagatgagta ttattttccc aaatctcatc aattattgtg ttatctaaat taagagtttt
     3001 ttgttcctga tggaagtagg aaacatgtac attagttcca aatttaatat tgccactaag
     3061 aggttgtagt tcattagtta ttattttaaa taatgtagat ttgccaacac catttgcacc
     3121 tataagtgca actttttccc ctctatatat atctaaatcc aagtctttaa aaagtattct
     3181 ttctccataa cccatagata catctctaat ttgaagaaca tcattaccac tctggacaga
     3241 aggcgtaaat tgtatacgag cttttttcct ataagcttct ggtttatcta aaacatctac
     3301 tttgtctaat gctttttctt tacttcttgc acgctttagg tgtttttctc taccataagc
     3361 ttttagtctt tcaattgatt cttcttgctt ttttatttct ttttgttggt cttcaaattt
     3421 cttaagctct agttcttttt ctattttaga taactcaaca aatttagagt agttaccatt
     3481 atatacttta agctttttat tgtgaacttc aaaaattcta tttacggatt ggtctaagaa
     3541 atatctatca tgagatatta acatgacagt ccctttatat tgttttaaaa atacttctaa
     3601 ccattctatt gcttcagagt ctaagtggtt agtaggttca tcaagtaaca atagagttgg
     3661 tttcttaaga agtaattttc ctaaaagaac tctagttttt tcaccaccag aaagtatgct
     3721 tattggctta tccatatcat tgtcactaaa tcctaatccc tttagaactc ctttggcttc
     3781 agatttatat ccatatccat ttaaatctga aaataattct agtttatgtg aatattcatc
     3841 catgattttt tctataattg gagagtttgt ttttgtactt tcttcagata ttttaacctc
     3901 caattctctt aaataggatt ccatttctat caaattttta aaaacttcta gtacttcttc
     3961 caaaatagta ttatccgaat aaaaattggt attttgttct aaatatccga tttcacaatc
     4021 tttagaagtg taaatatctc cactatcata tccataaatt cctgaaatta ttttaaataa
     4081 agtagttttt ccagtaccat taacaccgat tataccaatt ttatcgcctt catttactgt
     4141 aaaactaata ttttctaata tagaatctat accaaaactt ttatttaagt tattacatga
     4201 caaaacaatc ataaatttct acctccttga actatctaaa attataatgt tttgatataa
     4261 tataatcaag gttatatgta ttagttttga aaaagaaata ttttattgtg aatcaaacaa
     4321 aaaagaggac acttttagga ggtgaagatg ttgggaaata aaaatatatc aatggcagtt
     4381 ataagaaggc tcccaaaata tcatagatat cttggagact tattagatag ggatatacaa
     4441 agaatatctt ctaaagaatt gagtgatata atagggttta ccgcttctca aataagacaa
     4501 gatttaaaca actttggtgg atttggacaa caaggatatg gttataatgt agaagctctt
     4561 catactgaga taggtaaaat tcttgggttg gatcgaccat acaacgcagt tcttgtagga
     4621 gcaggtaact taggacaagc tatagccaat tatgcaggat ttagaaaagc tggattcgag
     4681 ataaaagctt tatttgatgc aaatcctaga atgataggtt taaagataag agagtttgaa
     4741 gtattagatt cagatacttt agaagacttt ataaaaaaca ataatataga tattgctgta
     4801 ttatgtatac ctaaaaatgg agcacaagaa gttattaata gagttgtaaa agctggaatc
     4861 aaaggtgtat ggaattttgc acctttagat ttagaagttc cgaaaggtgt tatagttgaa
     4921 aatgtaaact taacagaaag tttatttacc ttatcgtatt taatgaaaga aggaaagtag
     4981 acaacttaaa catattaata atgagcagtt gtaaagagta ttgagaaagt cagaagattt
     5041 aatattaaat cctctggctt tttgaaatat taggataaaa atttaaataa tgtatggaaa
     5101 taaacaatat taaggagagt ggtttttgtg gaggaattat ggaaaaaggc aattgaattt
     5161 catggtcatg aatgtccagg gttagctata ggatttaaag cagcacttgc agcaaaaaaa
     5221 tatttaggat gtaaacagtc aggagatgag gaaattgtat gtatttctga aaatgatgct
     5281 tgtggaatag atggtataca agtagtgcta agttgcacaa tgggtaaggg aaatttacta
     5341 cttaggatga ctggaaaatc agtatatcat ttctttaata gagaaaatgg aaaatctata
     5401 aggatatatg taaagtcaaa accatttgag atggatagag aaggatacaa aagatattta
     5461 ttagaaagtg attttgaaga aatatttgag attacagata ctaagttaag acttcctgaa
     5521 aaagcaagaa tatttaaatc ccttaaatgt gaagtgtgtg gtgaatttgc atctgagcaa
     5581 tatataagga ttgaagaagg aaagaaagta tgtcttgatt gttttgataa atatgaaaga
     5641 ttttatgaag agtattaaaa ttataaatta gattaaagtt aaaagtatta gatatgtgct
     5701 aacagtattt taagatgaat taggtagcaa cataataaag tatataaata atattaattg
     5761 aatcatacat aattaaaaag aggctgatta gtatttataa aataaaatca gtctctttat
     5821 gaataacgaa ttattattct ggttgaggtg catctacagg acaagctcct gcacaagaac
     5881 cacagtctat acaagaacca gcatctataa catatgcgtc gtctccagct gatatacagc
     5941 taacagggca ttcagcctca caagcaccac agcttataca agcgtcagta attttatatg
     6001 ccattttgaa atcctccctt ttatatgtat tgtaattcaa taacattata acaaatatta
     6061 ttgaatataa caattaaatt aattctacaa caaaaacttt attatgatat tcttgtttta
     6121 aagttttaca ataaagttta atctgcttat atttttattt attttaaaga agtttatttt
     6181 aaaaataaaa ttaaatttaa aaagttatgt attgattata tttaaaaatg ttatactcta
     6241 aaaaagtata ttttatttaa aaatttatta atacaaagga gatttactat gaaaaataaa
     6301 ttagtttaca tatgtattat gagtctattg ctatttgtag taggatgttc taataatcca
     6361 aataaggaaa gtaccattaa aaaagactct aagaataacc aaagccaagt taaagaagaa
     6421 aaaagagaac ctgtgaaaaa agatataact ataagtttcg ctggtgatgt aactatgggg
     6481 aactataaag gttcatcata ttatggcagt tttgaccatg aatttaaaag acaaggagaa
     6541 gattacaatt attttcttaa aaatgtaaaa cctgtatttg aaaaagatga cttaacagtg
     6601 gttaatttag aaggtccact tactacagcg tcaaatgcaa aagaaaaaaa atttgcattt
     6661 aaaggaaagc ctggatatgt aaatatttta aaatctggaa gtgtagaggc agtaagtatt
     6721 gcaaataatc attcagaaga ttattttgaa gaaggaatga aagatacaca gtttatattg
     6781 gacgagaata aaataaatta ttttggatta gggaaagatg ctgttgtaga tgtcaaagga
     6841 attaaagtgg gtctattagg gtataatgga ttatcaactg aatataatga aaaaaattta
     6901 aaacaaatgg aagatgatat taagtcctta aaaaagaaat cggatgttgt tgtagtgtac
     6961 tttcattggg ggatagaatt agattattat ccagataaaa aacaaaaaga ttttgctcat
     7021 tatgctatag acaagggagc agatttagtt atggggtctc acccacatgt gattcaagga
     7081 atagaaaagt ataaaaataa gtatatagct tatagtctag ggaatttttg ctttggagga
     7141 aataagaatc cttctgatac agatagttat atatatcaac aaacctttac tttttcagat
     7201 aataaattaa cttcaattaa agagccaaat ataataccaa cttcaataac atctagtaac
     7261 tccagaaata attatcaacc aaaaatattg gatggaagtg agaaggatag agttttaaat
     7321 aaacttgaaa aaataagcaa agatttaaat aaataaaatg taaaaaa
//
LOCUS       DAEPUT010000136         7221 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.140, whole genome shotgun sequence.
ACCESSION   DAEPUT010000136 DAEPUT010000000
VERSION     DAEPUT010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7221
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.140"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(52..714)
                     /locus_tag="KRL22_003643"
                     /pseudo
     CDS             complement(52..714)
                     /locus_tag="KRL22_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(874..1411)
                     /locus_tag="KRL22_003644"
                     /pseudo
     CDS             complement(874..1411)
                     /locus_tag="KRL22_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
     gene            complement(1484..1897)
                     /locus_tag="KRL22_003645"
     CDS             complement(1484..1897)
                     /locus_tag="KRL22_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH1274071.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            2390..3028
                     /locus_tag="KRL22_003646"
     CDS             2390..3028
                     /locus_tag="KRL22_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HBH1274072.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEGTI
                     SDMQSNINGIEGTISSMQGNINGIENTISGMQGTIGDMQGSISGMNGTISDMQGSISS
                     MDGTINSMQDSITDMQVEIKEVNSRLDNMEPDIKDLKTGQVETSSRLDTIQSDVTEIK
                     SDVKINRNTLDTVIKHTSSLVKDTSDIKNDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(3636..3815)
                     /locus_tag="KRL22_003647"
     CDS             complement(3636..3815)
                     /locus_tag="KRL22_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1274073.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDKSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(4041..4574)
                     /locus_tag="KRL22_003648"
     CDS             complement(4041..4574)
                     /locus_tag="KRL22_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH1274074.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQITVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIVPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            4891..5241
                     /locus_tag="KRL22_003649"
     CDS             4891..5241
                     /locus_tag="KRL22_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274075.1"
                     /translation="MGKVRIGCKKEKYFYVRNPVKSLVDRITENEQFAIYHFTHKYNW
                     RNKVFSILQRLIRLEKSKNELYMYEALVSASFLWLIMIKNIVLPPIKHKNIINIHMQK
                     ILRYIEKYYCFTLY"
     gene            5210..5529
                     /locus_tag="KRL22_003650"
                     /pseudo
     CDS             5210..5529
                     /locus_tag="KRL22_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429539.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(5831..6403)
                     /locus_tag="KRL22_003651"
     CDS             complement(5831..6403)
                     /locus_tag="KRL22_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1274076.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(6465..6728)
                     /locus_tag="KRL22_003652"
     CDS             complement(6465..6728)
                     /locus_tag="KRL22_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH1274077.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(6728..6949)
                     /locus_tag="KRL22_003653"
     CDS             complement(6728..6949)
                     /locus_tag="KRL22_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH1274078.1"
                     /translation="MGYLKEDKQGYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
BASE COUNT         2569 a         1212 c          882 g         2558 t
ORIGIN      
        1 tttagctact aactcatgac taaagtcaca agtgtgcgta gctatttttt aatcaaactg
       61 gaatacagac tccattccta ggaaattggc tgaaatatag tctgctgtca aagatgctgt
      121 catcacagaa attaaaacag atactgaaaa gtttttatgg acttcttcaa gtgaaaacat
      181 aacacccgcc agtggtgcat gaaaggctgc tgataatcca gcacttgccc cacaggttaa
      241 caggaatttt tcctctgtct tccctcggtc aagagctcta gaaatacctt tacctgccat
      301 agcaccaagc tgaatggaag gaccttccct tcccaaagca agaccaccca tgagtgataa
      361 gaatcctcca ataaattttg ttggcaacac tcgccaccat acttgtttta ttttccctgt
      421 catttccccc tcaagctgag ggataccact tccagaaatc attggctccc agtccaccaa
      481 ctttgataca atccatgcaa gtactgcaag tactgcaaac caagctatta tttttattgt
      541 agaaccttct acaaatttta aaatttggct aagccaagta ccagcctgcc ctaaaagtat
      601 cctgtataaa agcacaatca aaccagccac agccccaacc ataagtcctt caccaatcaa
      661 aattacctga aagtgctctg cccgtttgat aatatgagat gtatcctttt tcatactatt
      721 cctccttcat ccaataattc tacacaatct gaatctccaa tgactaaagt catgagtgtg
      781 tacagatatt ttttaatcaa caaaaataga tttttactta ctaaatataa gaaaataatt
      841 gctcaatttc tcaataaatg tgaatttatt cttttaggta tttattctcc acagtcgtgc
      901 ttcttccagc aaaatattta ttaattcttg ctttctctgt gtatagattt tacgattgtc
      961 ctcaaactgt aatgctaatt tttgtttatg actatcatag agttttgctt tgtctgtaaa
     1021 agtatttaga taatctcgaa aattgatata attattccat gcaacactat tccattcaac
     1081 aacatgaata tggtgagtac gagtattttt ctcaaaatct cccatagcaa aaagtaattg
     1141 ttttggtaca tcctgacctc gaaaaacgat tccacattgc tctaaccttt cgaggtataa
     1201 tttagccttc ctctaaagaa gcaacaccta caacaatatc aataataggc tttgcgctaa
     1261 tactgggaat agaagtgctt ccaatgtgtt gaatatcaat ggcagtctta tcccatatac
     1321 ttttcaataa tataatgaca tcttttgcac ttttatccca tatcatctga tgttccaata
     1381 atttaaccat accacatttt aaacctatca ctatatacca cctcaatata atccaccttt
     1441 atatatatta caattttttc tatcttgata aatagtgatt tagctatttc actttttctt
     1501 gacactcgct acattcccta tcatgaatag atataattcc tccacattta gaacaagtat
     1561 atctctcctt ctgcttttgc ataaacttct ctaaaccgta ctgctgaaca aatttactat
     1621 tttccataag gcttgcttga tatctcttgt tataactttt ttcaagattt tttatgagtt
     1681 tacaaggaaa attgaaacat tcaaaacaat aaaacaaccc tttttgacag acacaatcct
     1741 ttattttaca cttacggcag tgttctggct ttcctgtatc gccattcaaa caaccagcac
     1801 atggcttttt gtgataacaa tgcttatagc aaaccataca attcattcca caaggagcaa
     1861 acataatcgt atcaatactc tcttttggca ttttcataac attttactcc tttcaaaaat
     1921 ccaatttgtc gaattgttat atattcatat tgtaacataa aaaatagcta aaaaattcat
     1981 gcactttcat tgccaataaa ttttcaagga aatatgaaag tttaaaacta agaataaaaa
     2041 gagataaaaa ggaagctact aataaaaata ttcaaataca agtaatcaat ataaataact
     2101 taaggtatat ttaaaagtat atgatattac cagcagtttt aaatacaaat ataaccacac
     2161 atgcctcaaa aacacttatt acagtatctt agaaacttag acaatacata agattcatta
     2221 ataaaaaagt tctcaatata gtcattaata aaaacgttct caatatagat atatttaacc
     2281 atgttttgaa tagcagataa ttatatgatt aaaaattaaa tatgacatag cgtttgtgga
     2341 atataacacc taaattatgt tataataata aaacaggagt gtgatagtga tggatgaaaa
     2401 aatattagag ttattacagg aaatgcaagg taatattagt aatatgcaag gtagtatcag
     2461 tggtatcgaa ggcactatta gcgatatgca aagcaatatc aatggtatcg aaggcactat
     2521 tagcgatatg caaagcaata tcaatggtat cgaaggcact attagtagta tgcaaggcaa
     2581 tatcaatggt atcgaaaaca ctattagtgg tatgcaaggc actattggcg atatgcaagg
     2641 tagtatcagt ggtatgaatg gcactattag cgatatgcaa ggcagtatca gtagtatgga
     2701 tggcactatt aatagtatgc aagacagtat tactgatatg caagttgaaa ttaaagaagt
     2761 caatagtagg ttagacaata tggaacctga tattaaagac ttaaaaactg gacaagttga
     2821 aactagtagt agacttgata ctattcagag tgatgttaca gaaattaagt cagatgtaaa
     2881 aattaacaga aatacattag atacagtgat taaacatacc tcttcattag taaaagatac
     2941 atcagatatt aaaaatgatt taaataatat agagatagtc acatctaaga attcgaatga
     3001 tattgctaaa ttaaaatcag ttaaataata tactatagta aaaaatacct gaaaatttca
     3061 catacttctt taaagttata ccaaatttta tacagaaata ctgattatcc gacaacacac
     3121 tttacttata aataatttat taaaaaaata ctcattttat cctaaaatta acacgactaa
     3181 atgagtcttg atataataat aaaaaataag ggagattgga cactaaaaag ttgtgtatct
     3241 cccttatatt ctataatata gttatataat ttttcagcct aaaataaaag tccatctttg
     3301 attaaaacac atccccttat cacttataaa aggataaaat cttgttttca tttttccatt
     3361 tatatcttct tgcttaagag taataatttt ttcttttgat actttaagtg tttggttaaa
     3421 tttaaccaat cgactaagtt ttgttcaaca tctatttttc atattttcca atacttaatc
     3481 tattttttat aaataattct ttcatttcta actcacttac attttttaca taaaacgaag
     3541 catataaatt tcaaccttat cttgtatggt tcttaatact taatgagtag cttaagtatc
     3601 aaacattata aattttcccc ttacatttaa cactcttacc atttccaaaa tatacaaaat
     3661 atattttgaa catttgtaca atgatgaaat acaatacatg aaaatacaat atcataactc
     3721 ttgtctaaaa atagaagttc ttcaacataa cctttcacaa aaaacatatt atctaagtat
     3781 tttttgtctg ctccttgttt tcctgtttgt agcatataaa ttactgcatc taaacatata
     3841 actactcaca cgaaaaaaga aaataaactt ccaaaataca agctctaaaa actacctcta
     3901 aagttgtata atgtttacta ggaataaggt tgtataacat atagtttaaa taatcatttt
     3961 ttaaaattgc aagttattgc tttcaaaatt agatgtttgt atatcaaata aatgattaag
     4021 aatttctaaa tttaatggct ttataatgca ctccctttct ttgggataaa ataatgttgc
     4081 acagatactt tttctaaaga taacaatttt atttttctat caattccacc agcataccct
     4141 gtcaaactcc catttgttcc tacaacacga tgacatggaa caataataga gattccatta
     4201 tgccctactg caccaccgat tgcttgtgct gacattttag atattccttt ttgttgagca
     4261 actttatatg caatttctcc ataagtgatt gttttaccat atggtatttg ttgtaaaatt
     4321 ttccacactg taatctgaaa aggagtacct accatatgga gtgatggtgt aaaattgggt
     4381 tcttttcccg aaaaataaat atctaaccat ttctttgtct gctcgaaaat tggcaattct
     4441 ttttcttgat gttcttggtc aagattataa gcataatact tttgattctc aaaccaaaga
     4501 ccagttaacc caatattatc tgatgctaaa agaatatttc caattggact atggtaatag
     4561 ctaatatatt gcatacaatt cctccttata ttctgaaaac ttcactcaaa tcattagaca
     4621 cttcttttct atctgccatt atgtaaaaac atactaatat aatttccttc taactacact
     4681 ttcgttataa tatctatcct catatcatat tagttttata tttacctgca tctgttcatc
     4741 cttttttccc tttccctttg atgaatataa aattcataca tttaagcttc ctactgtatt
     4801 aacttttata gaagtgtata ttataatttt atcaccaaat agaccaaaaa aatatcgata
     4861 tagcatcaag taatatcata atactttcaa atgggaaaag taagaatagg ctgtaaaaaa
     4921 gaaaagtatt tttatgttag aaatccagta aaatcgttag tagatagaat aacagaaaac
     4981 gaacaatttg ctatttatca ttttacacat aaatataatt ggcgcaataa agtgttttct
     5041 attctacaac gattaataag gttagaaaaa agtaaaaatg aactgtatat gtatgaagca
     5101 ttagtttctg cttctttcct ttggcttatt atgataaaaa atattgtttt gccaccaata
     5161 aaacacaaaa atataattaa tatccatatg caaaaaattt tacgttatat tgaaaaatac
     5221 tattgtttta cattatattg aagggtacta ttgtgaaaac ttaattttgg agtactatca
     5281 agcagtgata atatcaataa atcagagtgt tccagaggat ttgaactaag tttaaatact
     5341 ataccttgta aatattttac tgagttttgt ttactaaaag caactcaatt tctaaaaggc
     5401 acaaatgagc taataagtga cattgctata aaagttgttt ttcatcaaat aatctatttt
     5461 agtaaatgtt ttaaagaaaa aacgggatat tctccaaaag tgtacagaaa tataaaaaaa
     5521 gagatatgat tttttatttc ttttgattat ccaaagagta aataaaaaat attgtaaaaa
     5581 acttactaac aacgacaatg ctttgaacta tggtaatact ttgaactttt gattggactt
     5641 tttttgctaa aataatatat ttaaatagca aagtaatctg tttaatcaat aaaaaataag
     5701 agataaaaga aatcaactaa aacttttacc tcttattttg atagtttatc agagctaata
     5761 tttacactct ttttattttt gatacttcat taaaaatgat gcttattctc cattcacttt
     5821 caattcttca ttaaaactga tgcttgcact ctgtaaactc ataaacatcc attaatgctt
     5881 caccaaatct ttgatagtga actacttccc tctcacccaa aaatctcaat atatctttca
     5941 aatcagggtc atcagttaaa tttattaatt gatagtacgt agccaatgct ttttgttcag
     6001 cagccatatc ctcatgtaaa tcagttaccg aatcgccaaa gacattaata taacttgtag
     6061 taaagtttac tccattagaa tctactggct gaagaccatg tccaaaatta gcataattac
     6121 taccaagtcc agcagcctta agctcttctg gagtacaatt gcctattaat tgatataaca
     6181 ctgaagaaat tatctcaaca tgagccattt cctctgtacc tatatcagtt aaaagtgcac
     6241 gagattttcc agttggcata gtatatcttt gttgaagata tctagttgca gctgccaact
     6301 caccattagg tcctcccaac tgagtcatga tatattttgc cattctaggg tctgcttgtc
     6361 ttatgttaac tggatgttcc agtgtttttt gataaatcca catattatct tactcctcct
     6421 taatatatat ttaataataa atctaatttt aaagtttaat aattttattt ataaaatgat
     6481 ttgtcccatg gccaaggttc agatatccat gaccaaggat attcacttga ttcatatcca
     6541 aaattagtta atgctccata tttagattca taatcacaca cagcttgtgt aaatttatcg
     6601 cagtatctgt tgtatgaatc aagagctttc ttatcccttg gattgttatc taaatataaa
     6661 tttaattcta tacaggcaaa ttgatattct gaaattctct ctaaaagttc tcttctattt
     6721 aatgacatta gtacatgtta cccccttttt tagctctaac tctattttta ggatttgcat
     6781 atagccaatc attatagtta tttgactcta ttaaatctaa ttcaggaaat aaagtacctc
     6841 tttttaatgc tgtttttgga ttgtatgtgt catcataaat ttgacgattg atgtatggtc
     6901 tagcaaattc acaacaatag ccttgtttat cctcttttaa atatcccatt aattatcctc
     6961 cttaattttt agaattttaa aatagcatta tttttaaaaa ttgtatactg gttctatatt
     7021 ataactggta gttttaatag gtctttaata aggttaaatg attaaataag tatctttttt
     7081 tcttatttta cctctaaaat ttttctaatt aatctttcat aaatatctat tttaaataaa
     7141 taatatagag tttatacaat tttttatagc ttaattacta tttactatat attattcatt
     7201 tttaaataaa atgtgattat t
//
LOCUS       DAEPUT010000137         6983 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.141, whole genome shotgun sequence.
ACCESSION   DAEPUT010000137 DAEPUT010000000
VERSION     DAEPUT010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6983
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.141"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(941..2155)
                     /locus_tag="KRL22_003654"
     CDS             complement(941..2155)
                     /locus_tag="KRL22_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH1274079.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            2592..3308
                     /locus_tag="KRL22_003655"
     CDS             2592..3308
                     /locus_tag="KRL22_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HBH1274080.1"
                     /translation="MKHIKIAAGLAHVNYGHISAIVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            3443..4069
                     /locus_tag="KRL22_003656"
     CDS             3443..4069
                     /locus_tag="KRL22_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1274081.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(4269..5813)
                     /locus_tag="KRL22_003657"
     CDS             complement(4269..5813)
                     /locus_tag="KRL22_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1274082.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(5839..6480)
                     /locus_tag="KRL22_003658"
     CDS             complement(5839..6480)
                     /locus_tag="KRL22_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBH1274083.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGIK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            6750..6941
                     /locus_tag="KRL22_003659"
                     /pseudo
     CDS             6750..6941
                     /locus_tag="KRL22_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
BASE COUNT         2571 a          897 c          970 g         2545 t
ORIGIN      
        1 aattttaaga taatgcacta tcaacacact cttaagtttg cttctaagtc ttatttccat
       61 aactttaggg ttaaccatac gcaagaccaa tcactctcgg acaatactca tgattttcgg
      121 taaaaaacgt aaaagaaata agaacaatta acaaaatgta taataacaat caatagcgac
      181 taatgatttt catgtaaaag gacaccaaac tatacggtgt ccttttcaaa ttcttacgtc
      241 atatcaaggc tcattcaatc gtggtaaatt cgtggtaaaa tgagtgcttt cctatatttc
      301 aaaatgcttg aaagtatagt gtttatgcgg ataatcaaaa atcagatata aaatttatta
      361 ataaatatta cattaatcta ttgttctagt taaaatcgta tttcaattaa attcaattaa
      421 aataaataac tctttataaa aagcaattat ttaggtagag gaatatttgc taactttaat
      481 agtctttgtt aactttaatt ttatttaagt tattatagtc ttactaattt tataattgta
      541 gatttaacta ctttatgttc ttttattgtt tatgtagttg atttagaagt tattttaacc
      601 atttatttta attgaagttg tttgactttt aaatcctttg tgtaatcttt gtttttctag
      661 ccatgataaa agtatttcta tttgtatcac tatatataat aatatcatga caaaatattt
      721 attgtctaac taattataat ctatccaaaa tgaaaatggg tgtgagatat tattacaaca
      781 aattgtatta gtattaaaaa gattaaaaaa ttaaaaaact aaacagttaa ataattaaac
      841 gattaagtga ctgtcatata acaatttata attttattta acagccactt aggtatttaa
      901 gagcgataga attgagtgta tatcaaatta taataatttc ctagtaaata attgaaaaat
      961 aaggtagtcc atttttatat ttgatatctg gtttaccttg aataagtgga tatagataat
     1021 ttagggcttc atcagttata taattacatt cttcatttat ccactcttta ggaaaatatt
     1081 ttgtcttgtt agctatttta gaaatatcag tatgactaac ttcatactta taaggattat
     1141 tgcatgttct attaatgata gccataactc ctgtatatcc ttttttagat agttctatcc
     1201 catatgcacc aacttcagct gcttgtttta aatcagtatc tgaagctaaa tgcatagcac
     1261 atctttgtat tacaccaagt tctaaggttt ttactcttgt tgtaattgat gatgatacta
     1321 taagattctt tagatagttg cttactccac ctaattggga atgaccaaat ttatcatgag
     1381 cagaagtttt ttgttcgcat ataaagttgc cgtatttatc ccttatacct tctgatgcaa
     1441 ctatataagc cttatttttt tctttaaata tttttctaac atcttctata aacttatctt
     1501 catagaaatc aatttctgga aggtatatta aatcaacaag tggagtatca ttaagtctag
     1561 ctagtgaaga agaagctgct aaccatccag tatctctacc catagtttct actataaata
     1621 taccattatt tttgtatata gaaaaatcta agtatgtttc cattattagt gtagaaataa
     1681 gctttgcagc agaaccaaat ccaggacagt tgtcagttcc taataaatca ttatctattg
     1741 ttttaggaat acctataaat tttattttac aagtagtgtt tttgcagtat tgagaaaatt
     1801 tcatcactgt gtccatagaa tcatttccgc ctatataaaa taatgtatct atttcatatt
     1861 catctagtat atttataacc ctatcataat cataagaatt tattttataa tcagccagtt
     1921 tatatctaca agaaccaaga ccagacgaag gtgtttgctt taaatttaat acattatctt
     1981 tgtttaagga gtctgaatct attatatttt tgtttaatat accttcaatc ccattgatac
     2041 caaaatatac tttatcaaag tatttagttt ctaaattttt ttcataaata ccaactgcag
     2101 aagcattgat aacagctgta gggcctccag attgggcaat aatacagttt ctcattttac
     2161 atctcccttt cattaatatt gttatgaatg gtacttttta tcgagtaaat ttatatttat
     2221 agtctgatta tatattaaat gaactagcta tatcaattga gttagtatag acaataaatg
     2281 ccataagaat gtggtaaaaa actaactttt tatatacaat taatgtctat aatttaccac
     2341 aatataaagg tacttttaag gagtagtcaa agtgttgtga aaaaaaatat atcagtgtaa
     2401 tattaattta caaagcaaaa taagttcaca gttaacaaaa gcagaataag ttcataaaag
     2461 aaatatatac agcaataaaa gtaatgctaa ataaaagtaa tactggatta aaaaatatta
     2521 aaaaaatatt aaaaaaatat caaaaactaa tatttaatac taattaaagt aaaatatgga
     2581 ggtatacaaa tatgaaacac ataaaaatag cagcaggatt agcacatgta aattacggtc
     2641 atatatcagc catagttaaa gaagcaatgg atgcaggtgt agactacgta cattcagatg
     2701 cagcagatat gcatgactta aaaaatatgc aacttatggg tggtcatcaa ataatagaag
     2761 caataagacc agtgacagat aaaccaatag aatgccatat atacacaaga gattgtgata
     2821 gattatttat agaaaaaata gcagcagcag gatgtaactt gttgataata ccagcagaac
     2881 attttttagg tgctcctctt gcatacataa taaattactg tagagaattt ggtatgaaag
     2941 taggattaac aattggatgt tacacaccat tatgttttgt tgatgaagct atatatgata
     3001 tagatagatt gcaaatagtc gttcatggtg ttgatgaaac tgatggaaaa gataactggg
     3061 gatggagaaa gagtgctgtt gatttagtaa aaagagctag aaaaatgata gacgaaaaga
     3121 atcctaagtg tgaattagca atagatggtg gactaagagc agacaatatg gagccattaa
     3181 tagaatgtaa tccagacgtt gtaatattat cttcagcaat attcaaggat aaagatggta
     3241 taacagcagg tgttaagaat tgtagaaaag ctatagatga agcagctaca aagtttggtt
     3301 tagaataaga taataaacta tgataaaaga gatgctttct taatgtttta aggaagcatt
     3361 aattttatga aaaactacag gaagctagac taatttaatt gattttttat actgaaataa
     3421 tataatcata ggaggttatt aaatgaaaaa agaaatgata aaagattatt tactgataac
     3481 aatatcagca tttttaatgg cattagcagt taattttttc tttgcagaac atacattagc
     3541 tccaggaggg ataacaggat tatcagtcgt acttagcaca ttcttatcaa tgcctgttga
     3601 gaatatatca ttaggaatat ctatgccact tttagtaatg ggattattat ttttagggaa
     3661 aggttttgga ataaaaacat tatatataac tcttatgggc ccattattct taaaagtaat
     3721 accacaaact cacataactg acaatctatt agtagcagga gtgataggtg ggttattggt
     3781 aggaactgct atagggatag caataataag gggctgtagt actggtggaa ctgatttagt
     3841 tgcaatgctt attaataagg taattaagtt tctgaagttg ccagttatat tatttatgct
     3901 agatggattt ataatagtag cgtctggaat aataagtaag aattttatga tatctatata
     3961 ttcattgata tctttattac tcataataaa aacaatagga tttgtaacta caaagtttgg
     4021 taagaatact gaagaaatta ataatataaa taatgcttgt gctcaataaa aataataaaa
     4081 tttactttaa atataaaagt ttaaaaaata taaaagctta aataaaaaga ttaaatataa
     4141 aaaatgaagg tgtctcaaaa tgaatttttt agttcatgag gcactttttc tatgaaatca
     4201 aatatatttt tatcatttgg acaatgaaaa ataggtttat ctctatgttg agacaagcct
     4261 atttttgttt atttataaga taatatttta tttttttcag aatatagttt ttttataatt
     4321 gtactaagtc tagaaatatc attcttactt aaaagagcat ttatatttat cagttcagca
     4381 ttatgttcaa agtctacagg agcagtagtt agtattaagt ccacatcatc aaagttcgta
     4441 aatgaaatag aagatagagg tatagattta actatattaa tctgattaaa ttcaaaactt
     4501 aacttttgga ctaataaatt agatacacca tcactacagt gacatattaa aatagtatta
     4561 aggggagatt tgcttctatc tattgctgat attaaatata aagcaagata tcctatttcg
     4621 tcatcattga cttcataatt catcaactgt ttgataacag tattagactc tttagcagcc
     4681 ttataagtat aaggaaatgt tctctttata tcatttaata tgggatttgt aatagtaaac
     4741 ccatagttta ttctgtgtag aactgattta aggtgattag caagagactt tattaatatt
     4801 aaatcatcct ttaagtttaa gtttagtata cttccccaat gaacagctat tgcttcagat
     4861 agattatact ctgtaatttc ttcattttta agaggttcaa gagtagtagt tttctttatt
     4921 gatttaagta atccttctat atgaagaagg atataacaga cctcttcatc aataaattct
     4981 acgtcaaaag cttcacttag gttagcacat aaaatttttg atttttcaaa gtattcatgt
     5041 tctaataatt ctctaaaaaa accttcagat aagttaatat atcttttaat tgaaattctt
     5101 ttaatacata tagctatatg tattaagaag tttatataat actcatcact aaggttactt
     5161 ttttctactt gtaaggtgtg tagagtgatt tgagataatt tctcaaaatc atagttaaat
     5221 agctccttaa atatttttgt tgaaggggta tctttgcatt cattagattt cgagaataat
     5281 atttctttaa gttcagtata acttttatta accgtagcaa gttcaaaaat tgcttttcga
     5341 atatctttct cttttccctc taaatatact ccattattgg tttttctaac tagagtcact
     5401 ttaaagtttt gcaaaaaatt ttgaataact accaagtctt tatgcacagt agctctacta
     5461 acatgtagtt cattgcaaat atcacgaatc ctaaacttag aatttttaat aaataattta
     5521 cttagaatat acctttttct atcttcagga gagtatgcat atatacaatt tgatttatca
     5581 ttgatatctc taataacttt aagttttata tcttcattac ctagaataat aacccctgaa
     5641 ccagtttttt tatctaggga taaattaaac tctaaaagcc attcatctaa aataacaagg
     5701 tcattacgaa tagttttatt actaactttt aattcttcgg caatagtatc tacagtaata
     5761 tagtctgagc tgttgagtaa taattcagca atatctaata atcttttgtt caatgcaaac
     5821 cctcctaaat cttagttact atttattaac cttggaccaa tctctttcaa aagtattggc
     5881 accatctatt gtaagctggt taaaagaagc ttttttaaat aaatcatatg ttacagctgc
     5941 ataatcacat ccacaaagag atgcttgagt taagtggaat acatttttaa tagaagctgc
     6001 aacaacttta gtattatatc catttattga tataaggtta catatttctg taaggttttt
     6061 tataccatca ttcccatttt catcatttct acctataaaa gggaataggt aatcagcacc
     6121 tgcatttata gctaatgatg cttgatttac attgaaaatc aaggtacatg cagtttttat
     6181 acctttacta tttaatatgt ttataagttc taagccaact tcagagaaat ttatttttat
     6241 tatagtgttt ttatttatat ttaatatctt atcacatgaa ttaattaatt cgtataaatt
     6301 atttccaatg acttcagcag ttaatatttc tggatttaaa ttagcacatg tctcaataaa
     6361 ttcatggaag tttactttct ctttaagata catagatgga ttagctgtta ttcccttaaa
     6421 tccatacttt aaacactttt gaatttcatc aagattagca ctgtctatca aatatttcat
     6481 aatttaattc tcctttaagc tatttgtcat aaaaaagtgt atatactcta tttttattat
     6541 taagtcaatt atacaataag attgattata aaattataac atgggtactt aataaaattt
     6601 acataatgat atggtaataa taaaacattt attgtctaat aattgccata agctttagta
     6661 aataagagtt aacagtgaag gtattgcctt aaaaatccta tgatatgtat aatttgaata
     6721 tgaaggcaat aatttaaggg aggaaaaata tgattaactt ttatcaacca tcaagaataa
     6781 attttggaca aggaacttta agtgaattac ctagaataat aggaaaatat ggaaagaaat
     6841 gtttgttagt tactactcca aatgtagagc cattagacaa gttatataaa agagttacat
     6901 tgaatttaat agaaaaaggt atagaagttg tacactttga ttaaaaaata gctacgcaca
     6961 ctcgtgactt tagtcatgag tta
//
LOCUS       DAEPUT010000138         6881 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.142, whole genome shotgun sequence.
ACCESSION   DAEPUT010000138 DAEPUT010000000
VERSION     DAEPUT010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6881
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.142"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..138)
                     /locus_tag="KRL22_003660"
     CDS             complement(<1..138)
                     /locus_tag="KRL22_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274084.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KN"
     gene            complement(787..1194)
                     /locus_tag="KRL22_003661"
     CDS             complement(787..1194)
                     /locus_tag="KRL22_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274085.1"
                     /translation="MSKVAKAAFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1668..2552)
                     /locus_tag="KRL22_003662"
     CDS             complement(1668..2552)
                     /locus_tag="KRL22_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1274086.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2843..3319)
                     /locus_tag="KRL22_003663"
     CDS             complement(2843..3319)
                     /locus_tag="KRL22_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBH1274087.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEDVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQAKDLEEHHHHDENCGCGCNHHHEN"
     gene            3586..4761
                     /locus_tag="KRL22_003664"
     CDS             3586..4761
                     /locus_tag="KRL22_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HBH1274088.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4842..5645)
                     /gene="proC"
                     /locus_tag="KRL22_003665"
     CDS             complement(4842..5645)
                     /gene="proC"
                     /locus_tag="KRL22_003665"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH1274089.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAISSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5685..6269)
                     /locus_tag="KRL22_003666"
     CDS             complement(5685..6269)
                     /locus_tag="KRL22_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274090.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2266 a         1156 c          763 g         2696 t
ORIGIN      
        1 gtttttataa acatctattc ttttagcaag atacttatta tatacaaatc tacaacatcc
       61 aaaagttttg ttaattaact cttgttgttt tttatttgga tacattctaa acttataagc
      121 ttttttcact gctatcacct cactttaatt gttttttgat acacttttta atgattttat
      181 cacattttat cacatttaat atattatata atgctgtggt aaacaattta ttaatcacct
      241 ataataatgt taacaaatgt aattatttaa aacaattatt tagaaggttt tatatttaat
      301 tttaaataac atatttaaga accgtaagtc ttaactttta tcatttttga ggttgtcgtt
      361 cacataagtt cgctactacc tatgcagttc tcttatgaac ttcttacact ttcatgtaag
      421 cacagactat atcttatcct tcagcattat ccgttaaggt ctacccactt ccactaccaa
      481 tagcttgtag tgtacttccc tcaagaggaa tagtcgttga agtttctcct attcggagtt
      541 tacctgctga ttgcccattt taaagtactt aggatttaac cttataccat ctaaccaatt
      601 ttttctactt tcgtaacttt cacacttagg tttatttcat ccttatgttt tagtttgatt
      661 agctttaggg gtttccagca attcaagtag tattggatag gttctatcct atctctacat
      721 ataggtttcc ctatatgctg actattttag ctattaactc atgactaaag tcacgagtgt
      781 gtgtagctat tttttaatca atattttagt aaattttacg gtaagtaaaa acctctctcc
      841 ttcaaatcct atagcaaata tacttacaag ttgctttgag aaaataactc ctaatatagc
      901 tacaactatg catataccaa ctattatatt taaaacattg tttaaaaact ttagtgcttg
      961 cttttcacct tgtttactac ttatatcttg atacattgga ataaaagtag taactatagc
     1021 agtacctatt gctgcaaata taatatttgg tatattcata gctgttaaat aactctctgt
     1081 atataagcct gtaccataaa ttgatgataa tactaattct ctacccattc caagaatctt
     1141 agagattata gtaactatca tcaaataaaa agctgcttta gctaccttgc tcattttatc
     1201 actccacttc taacatacct ctttttaatc aagtaaaatt tagctcatta gatataattc
     1261 tatcaactaa tttgtcttgc ttagccctat caaaatataa ttaacaccta tttcttaata
     1321 tatcacaaac tacattattc ttcatatttt tttatttctc caataagttt tacatctttc
     1381 ctatataaat tttatagctt caattatatt caaagaaatg gagttgctac ccgataactt
     1441 taaaagtaaa aaacagattt tattatcttt ttaaactata ttctaaaata ttttgtccat
     1501 attgagaaat tttactaaac tattatgtac tttattaaat aaataaaata acagcacacc
     1561 tataaaatac aagtgtgctg ttcataaaca gattttataa aaaaataatt cctaagtaga
     1621 gattaacatg ctttctcata ctctcatata taatgtgtct aaaaatatta ataaaaatgc
     1681 tttaattgtt ttaacttact tggatgtctt aattttctta ttgctttagc ttctatctgt
     1741 cttattcgtt ctctggtaac tccaaatacc tttccaatct gttctagtgt tttagggtca
     1801 tcatcatcaa ttccaaatct cattcttaaa acttgctgtt cttgctctcc aagacctgta
     1861 agtagttctt ctatcttttc ttttaaatta tgctgttcaa cttcgtgtat tacaacatct
     1921 ttaaaatcag catctgatgg tataaattca actaaactac tatcctcatc ttcttttaat
     1981 ggagtatcca aagatacaac atttttatct cttcttaata attccaacac tttgtcaact
     2041 tctaagccac atgcatctgc aatctcatct atagttggct ctcttaataa tacatttaaa
     2101 agttcttgtt tctttttctt tacaaaattt attctctgat gaagatgtat aggtatccta
     2161 atagtatttt cgcaatcgtc gatatatctt gttatacttt gttttatcca ccaagttgca
     2221 taagtgctaa atttgtatcc ttttttataa tcgtactttt ctacagcttt tataagtcct
     2281 atatttcctg cttgaattaa atccaacata tcaatactat ctcttttata tctctttgct
     2341 atgctcacta ccaacctata atttgaattt ataaattttt cttttgctac tgaagatgag
     2401 ttgattattt ccttagccag ctctacctct tctcctgctg acaacatttt gtattcctct
     2461 atttccttta aatacatttt catcgcattc gatacatttg atgaacccac acaaatataa
     2521 ttttcataat tattttcttt tttagtatcc ataatcaaac cccttctatt catagaattt
     2581 gctaaaacaa aaataaataa tttaaaccta cataatctac aattacataa tatcccattc
     2641 tttaaatgaa ttgttttgta tattatgtat acaaatttat aaaaactata cctataatat
     2701 tattctactt ctaacagcaa tatcctcctt atatatataa tttattttat tatatgttgt
     2761 tatattctta gttttttgaa tgatatatgt ctaaaaaaag actgtttact aaacagtctt
     2821 tttttatata tatgctcaat atttaatttt catgatgatg attacatcca catccacaat
     2881 tttcatcatg gtgatgatgt tcttctaaat cttttgcctg ttgttccatt tcatgaaact
     2941 cttttaccat tatatcataa gttggaagag ctgcctcagt atcgtattct tcccctctcc
     3001 aatcagcgta catcatagca tctccattag ttaaaaccaa tctacctgac atagttatat
     3061 tatccacgtc ttctaaaaat tctatttgtt tttgtaaaac ttctccttct aactccacat
     3121 cttcatctaa acattgcact atcattacag gtgcataata atcttcttca tctttaacat
     3181 ttacaacaat atctaaaatt ccttctgcac cttcttcaaa ttctgccaac tcaacatttg
     3241 tatcaatcat atcttgaggt actaataaat cttctattaa atattttatt actctatctt
     3301 ttactaattc ttttgacatt tatttttctc cttccgattc tataacatta tcataatcat
     3361 ttctatatta tagtatacta cattaattgt tttttcaatc tcttacaaaa attatttttt
     3421 tattatcttc cttatattcc cttttttatt acaaagttgt aatcgcattg atttaaaaaa
     3481 tagtttatat ttagtataat agaaatgtag cacatatttt tattcaatat attaataaaa
     3541 aaatagattg aaaatgtaat gtatgttaaa tctaggagga atattatgaa gtttaaaaaa
     3601 caaattagtt ctattgttgt gtctactatg cttgtacttg ggagtatgaa cctttcttat
     3661 gcagacggta caaatgtagt tacacttgga gctaacttat cagagtctca aaagcagcaa
     3721 atgcttaatt actttggagt aaaaaaagac caagtcttag ttttagatgt aacaaatgca
     3781 gaagaaagac agtatttaca aggtgttgca acagagggtc aacttggaaa agttactatc
     3841 tcttgctcat acgttgaacc tactaaaaaa ggaaatggaa ttaatgttaa aacagcaaac
     3901 ttaacttggg taactagttc aatgattgct tcaaccctta caacagctgg tcttgaagat
     3961 gcaaatgtta ttgctgctgc tccatatcct gtaagtggta ctggagcatt gacaggaatc
     4021 atgaaagcat ttgaggatgc ttcaggaaag aaacttgatg aaactaagaa agaaattgct
     4081 tctgaagaat tggtagttac aggtgactta ggagatgata tagggcaaga aaaagcaaca
     4141 ggtgtaatga atgatataaa aacagaaatt gtaaagaatg gtacaaaaga taccaatcaa
     4201 atagcaaata caataaataa tgttgtaaat aattacaata ttactattac accagaacaa
     4261 aaagaacaaa ttaaaggtgt aatgaaaaaa atagctgacc aaaattacga ttacaatagc
     4321 atgaaaaata cactagataa tgtatcagat aatgtaaatg aacaattaaa gaaattaggt
     4381 gaaagtgtta agggttctgg tatactagat actattggtg gatggtttag tggaatagga
     4441 gactggttct ctggtttatt ctcaggcgga gataaaaaag atttgggaat cttaaataac
     4501 actaatgatg agtctcttgg ctctgatgct gtaataaatt ctacagaagg tgttcaaata
     4561 aatccacaaa ataatactaa ttctaacaat gatagtgata caaatagctc aaaaaatgat
     4621 acttcaagta ataatgaaaa taacgatagt tctcaaacaa atgaaaacaa cacaacaaat
     4681 aattcagaaa atcaatcaaa taataatgac tcagttggtt tctttgaaaa aataaaaaat
     4741 tggctttcag gcttatttta gaaattaaac aaataaaaag aattgcctaa aatggaaatt
     4801 ttctataaaa ggcaattctc tttatttaca ataaattttt attactcact cattttttta
     4861 gatttttcta tacatgcaca tattgctttt atcacagaag ctctaaaacc ttcttcttca
     4921 agtactttaa ctgcttctat agtagttcca ccaggtgaac ataccatatc ttttaattca
     4981 ccaggatgtt ttcctgtctc aagtaccatt tttgcagaac ccataacagc ctgtgatgca
     5041 aacttatatg cttgtggtct tggcattcct gcaattactg ctgcatctgc tatagcttct
     5101 ataaataaaa atacatatgc tggtgcagaa ccacttgcac caattacagc ttctataaga
     5161 tactctggta ctacctcagt atttccaaaa gaattaaata cttctgtaac tgcttctaag
     5221 tcttctttgt ttatattttt atttatagaa agagaagata tggcttcatt tacaagagct
     5281 ggagtatttg gcatagttct aactattttt ttatcttctc ctataataga ctctatatct
     5341 tttatagatt ttcctgctgc tattgtaact ataattttat tgtcatctat aaagtctttt
     5401 atctcttcca aaatatcatc atatatatct ggtttaacag ctacaattac tatatcagag
     5461 gttctagtta cttccttcga gtcttttgta gtatttattc caaaatttgc atctattcta
     5521 tcgagagttc cttgactata tgctgatgct ataaccatat taggttcaac taattttgaa
     5581 tttactattc cccctatcat agcgcttgcc atatttcctg cacctatgaa tccaattttt
     5641 ttcactttag tacctcctta ttgactaata gtaatcgtta aaatttaagc ttctttaact
     5701 gcatcagact tttcaaatgg atttggtata cttactacca aaattttcac taccttatta
     5761 gtatagttga cccaattatg attgttcttt tcactattat agtgtattgt gtctcctgga
     5821 tacatttcta tttgttcatc tcccaaaaac actgtaagag taccctctaa tacatacaca
     5881 aattcctcac cttcatgtac gtaacaacaa atttcctcac tactcttact tggaagaatt
     5941 tcaattaatc ttggtagcat tgttttttcc tttaaactag atgataaatg ataatgtata
     6001 aatgttgagt tttctacatc aaatacttct ttttcataac ttcttaatac agctctttta
     6061 tgctcttttg gcttcataaa aaagtaagtt aattctacat ctagtacact tgctattttt
     6121 cctaaggaat ctgttgccac acttgttaat cctctttcaa gttgtgataa aaaaccaatt
     6181 gacaagtttg ttttttcact catatccttc agcgtcattt gcttttgagt tctgagttgc
     6241 tttatttttg ctcctatgtc cttattcaaa accatcaccc ctaaataatt ttaatttttt
     6301 cataatataa atacaaaaat ataaatatag gtactgaacc tatctttatt tcatttaaaa
     6361 aaatttttat aagtattact ataatttatc aatctttttt tgtctacatt tttacgatta
     6421 tttacgattt atttttcaca tatgtatatt taatcttgcc aactaaagat acatttttta
     6481 taagcattta ctctttatat aataaaactt aagttgttca tgtagtcttc ttctggttta
     6541 attattaaaa tttcaaatta tattattatt tctacacatt attacatcct ttagtacaat
     6601 tataacataa ttttacaatt taatgatatc tattcaatgt ctttttttac tctacaacat
     6661 attttatttt agagtttaat actatatata ttttttatat acagccttgt cattttttag
     6721 attgtcaaga gttattgaag tattttatgt agatttagat tttatttcct aatttctcat
     6781 ttaacaagaa ttgcttatga taaaaaataa tatcatctca ataagattct tgtaaatata
     6841 tctatattct aaatataatt tctttttttg tcaaaatttc t
//
LOCUS       DAEPUT010000139         6739 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.143, whole genome shotgun sequence.
ACCESSION   DAEPUT010000139 DAEPUT010000000
VERSION     DAEPUT010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6739
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.143"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            428..1702
                     /locus_tag="KRL22_003667"
     CDS             428..1702
                     /locus_tag="KRL22_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH1274091.1"
                     /translation="MQFIDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVMD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYADIPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYVKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGISPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1909..2226)
                     /gene="trxA"
                     /locus_tag="KRL22_003668"
     CDS             complement(1909..2226)
                     /gene="trxA"
                     /locus_tag="KRL22_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH1274092.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2493..3245
                     /locus_tag="KRL22_003669"
     CDS             2493..3245
                     /locus_tag="KRL22_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBH1274093.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3232..4113
                     /locus_tag="KRL22_003670"
     CDS             3232..4113
                     /locus_tag="KRL22_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH1274094.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(4339..5694)
                     /locus_tag="KRL22_003671"
     CDS             complement(4339..5694)
                     /locus_tag="KRL22_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH1274095.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2597 a          956 c          838 g         2348 t
ORIGIN      
        1 tatacttgta catcttttat aacatataaa atcttttttt ctaattatat acaatatatt
       61 ttccattatg ttctaatcaa tttctttact atttttacaa ctttattagt catattcata
      121 attatttcta attagtgttt aacattttat gtaaaattta taaaaaaatg tatataaatt
      181 aaaataagtg actatactaa aaatatgata cggataaaca ataagttcaa cctatctccc
      241 ccaaaatcaa gtgagctaca gtttccccca actgtagctc attttcgtgt aatttaataa
      301 acatctcaac aagaattaat taacaaaacc ccttataaaa acataacata tattaaacaa
      361 gctcttgatt aaaacttgag cttttttaat aaaaaacaga atagtttatt agataagggg
      421 tttttttatg caattcatag atgtatctaa atacattgaa ggtgcaaacc ttaaagttaa
      481 aactaaaaat ggtgaaactg ttaaaagaat atattttaac aactctgcca ctccattagt
      541 tttaaaaaac gtaatggata acttaaactg tgagattcct tggcttactt atattaatgc
      601 tccaggaata atctcagaaa aaaatacttt aaaatatgaa aatgtacgct ctactatcct
      661 caaacttatt gatggagacg aagaaaagga ttctgttatt tatgtcaaaa atgctacaga
      721 aggaataaac ttcttagcaa aattttttaa agatgaaaat ccagataaat ttgttattac
      781 cacagcaatg gagcatatgg ctaattacct gccttttaaa gttaattttc ctacaaaagt
      841 tgttggaatt acagaaaaag gagaacttga tttatgtcaa ttagagaata tacttaaaaa
      901 ttatgctggt aatgtatctc tcgttacagt tacaggagct agtaatgtca caggtataac
      961 cactcctata tatgaaatag caagaatagc tcataagtat ggtgcaaaga tattggtgga
     1021 tattgtgcaa gtaattcagc ataaaccttt ttcaatgatg ccacatgaat gtgatgagca
     1081 tatagatttt gttgttttta gtgctcataa atgttattct ccactaaatg gaggagctct
     1141 ggtaggacct aaaaaattct ttgaaaaatt taatcctgta ctatatggct caggttccac
     1201 caaatttgta aatgataaca aaatactata tgcagacata ccccaacgtt ttgaagcagg
     1261 atacccagag tattttggaa ctcttgcaat gggaaaagca ctgaacactt taaataaaat
     1321 tggtctaaac agaatttcaa aatacgaaag agaattattt ttatatgtta aagaagaaat
     1381 gagtaaaata cctaatataa taatatatgg agataaatca aataatgtaa ttatcccaaa
     1441 tatatctttt aatataagta atatgtatta caaagatgta gcaaaatatt tagttgataa
     1501 ctttggaata gaaactggag ctggagtagt aggtgcagat atttatgtac aaaaattatt
     1561 aggtataagt ccaaaagaag catatgtcag atttatgagg gaaaatcctg taggtcttgt
     1621 taggataagc ttaggaatgt acaatacttt tgatgaggtg gatagcttta tacatgctat
     1681 taaaactttg gcttttaaat aagttttttc tattcttttt tatcaataaa tagagagtag
     1741 ttttgttttc acaaaaaagc aaattatatc aacagtcaat ttcattagca attagacact
     1801 catttgtaac tatacaaact attttacact atacaaacaa aaaactcatt acaatgagtt
     1861 tttttgttta tatatgagat ttattttaat tacttcaatt tactttaatt acatatatga
     1921 ttcaattttg ttttttaaat tctccttagg cataaaacct attaatctat ctacaggttt
     1981 tccatcctta aatattagca tagttggtac tgtagatact tcaaatttct gagctaattc
     2041 tatactttgg tctatgtcca ccttcaagaa gtttgctttt tcaaccatct catttcctaa
     2101 agcttcatat attggtgata gcatcttaca aggtccacac caagtcgcaa agaaatctac
     2161 aactactaaa ccatctttat tttctacttc atttataaat tcattattat ttattatttt
     2221 taccataata tacatctcct ttattatctt cttgatatta atatactacg ccctatataa
     2281 cagttcaatt aggcactttt ttgtaaccgc ctatttttaa taggtttaat attatgataa
     2341 atagatttat aagattaaat atttatgaga ctaaatattt ctaatatatt ttattttttt
     2401 cttaatatag ttgacatttt ttcccttaaa ttataaaatc aaattaataa ctacataggt
     2461 agttactaat cttttatcaa aggagtttct atatggataa tataattaat gaattacaaa
     2521 atataggatt tactaaatac gaatctcaaa tatacatatc attattaaag gaaagccctt
     2581 taacaggata tgaaataagt aaattatcag gtgtaccaca atcaaaagtc tatgaaaata
     2641 taacaaagct attaaacaat aatataatta tcaatgttgg aactgaccct attaagtaca
     2701 taccaataaa ccctaatgaa ttattaaaaa ataagaaaaa agaatttgac aattctatgg
     2761 ataatctaaa gaatagctta cagatattaa ataaaagtaa aagtgtagaa tacgtattaa
     2821 acataaaagg agataaaaat atattaaaaa aagcaataga aatgataaaa aatgcgaaac
     2881 aagaaattat aatttcttgc ccttatgaag aaattcttga attaaaaaaa gaactcctaa
     2941 ttgcttacaa aaaaaatatt aatattgaaa tactactttt agaaaacaaa agtctgaaag
     3001 gtcttgataa tattcatatt catggaggta ataaaactac acttgaaaat aaaatgcttt
     3061 acaaaggaat tattttgatt gtagataatg atgaaatatt gacaggaaac ttatcagaag
     3121 gcagtgaggc catttcaatt tggacaaaaa actctaacat tttatatatt ggagttcaat
     3181 acataaaaca tgaaatttat atttcagaac aaataaaagg aggttataaa aatgaacaaa
     3241 attaagatta aacaagttga tgcttttaca actatacctt ttggtggaaa tcctgctggt
     3301 gtcgttactg atgcctctaa catttctgat gaaattaagc agaatgtggc taaagaaatg
     3361 aatttatcag aaactgcatt tgtttcagag tcaaatattg cagattttaa agtacaattt
     3421 ttcacaccag gtttagaagt tgatttatgt ggtcatgcaa caataggtac tttccatgca
     3481 cttttggaag aagggaagct taatactaat aagagtatat tttatcaaga aacaaaagct
     3541 ggtgtattat ctgtagagct taagaaaata aataatgaaa atatatttat gatggaacag
     3601 aatacacctg aatttgaaaa tttagataat tgcagaaaag aacttgcaca aatgataggt
     3661 gtgcatgaag atagacttct tgaatatcct attataaagg taaatactgg actttggtgg
     3721 cttgtatttg gtctaaaatc tttagatgat ttaaaaaata tctctccaga tttaaataaa
     3781 atcaaaaaat ttagtggtga taataatata attggtataa ctccattttg tatagaaact
     3841 atagataaaa agtgtgacta ccatttaaga tctatagcac catatgttgg agttacagaa
     3901 gaccctgtat gtggaactgg gaacgcttgc gtatcatctt atatagtaca tcacaatatt
     3961 ttagataaaa ctagttttat tggtgagcaa ggtaacttta taaacagacc tggaaaggta
     4021 tatgtaaata taactagaga aaacaatgac ataacttctg taaaaattgg aggaagtgct
     4081 tatactgttt taagtggtga aattatgtat taatcccata cctaataaaa acaaataaaa
     4141 atactagcta actaaagcta gtatttttat ttgttatttt tatttaataa tcatactcta
     4201 acaaatatta taattatata tatcataata ttgtatttag aagtaaaatt ttatttttat
     4261 tattaattag ttataaatca atctaataca acataattac agtagattaa cctataaaac
     4321 ataataattg cttactaatt atttatcatc ctcaacaagt ctacttaatg tcttatcaga
     4381 taagaataat aatatcgctg caacaaatag tattactgga attatagtat atactttaat
     4441 catatcaaat ttaagagtaa atgcatatat atatccatat cctttaccag ctataaaagt
     4501 agcaaatgtc catactccca taagaacacc tagaagcttc ttaggtgcat acttacttac
     4561 aaaagagtta ccaagtggtg agaataacat ttcaccaaga cttaaaagaa taccaaacat
     4621 gattatccat agtatactag ctttagcagt ttcaggagct ccaactcctc ttgaaaattc
     4681 tgcaccaaca agcattaaga atgcaagacc taagaatatt aatccaagac ctgtcttttt
     4741 aaataaactc atatctcctt gtggtctact agcaagttta aaccataatg ctccaagaac
     4801 tggtcctaat actatacata caagtgaatt taatgagtca aaccaagcaa gaggaacatc
     4861 aaatcctcca acattcatgt ttacaaatgc tgcaccataa tcataaactg caagataagt
     4921 tagataccag aatacccaga aaattacaga gaagaatgat ataagtataa tagcccaaat
     4981 tctcttctta tccatgcttg taagaggaga cttatctttt tcttcaattt tttcagcaac
     5041 tacaccttct ttaaaaggtc tctttcctgc attcccaagg aatctccatc catatatgaa
     5101 ccatattgca cctattacac aaagtacagc tgctataaag aaacattgag aaaatccaag
     5161 tacaccattt tttgcaaatg ttttaaggta aagaatacca actgctatag taccaataaa
     5221 agaacctata ttaacaaaag aatactgtac tgaaaatgct gtatcaagtt cttcttgact
     5281 atcaaaaagc tgtccattta ccgcagatac gttaccttta aagaatgcag taccaattga
     5341 aactaagatt atcattgcat ttaccataga aactgtagtt gcaatagaac caagatagta
     5401 tcctactccc atgataagca tacctatagg tatagtatat ctagctccta tccatctatc
     5461 tgatatatat cccccaatta taggtgcaag gtatgtgaat gcaacaaggt tggcttgcat
     5521 tatagcagct tgtcctttat ctattccaag accaccatga actatagctg ttgtaaggaa
     5581 tatatatatt aagtactttg aagcataata tgctgctctt tcaaatgaga aagttgttga
     5641 gcagatataa aatcccatag gaaatttacc cttctttttt actgttgagc tcataatttt
     5701 aaatcctttc ttaattgtat ttttattttt tacgttttgt ccaaattctt tcttttatga
     5761 aagatataat attattattt tgtaaaacaa tttgtaatta ttattaagat aattgcgcat
     5821 ttatttgtag agtacatatt ctcatggaat aaaattaata cacttcttaa tcataaattt
     5881 aaattatata aattcactat tttcagatat agttataaat taatatattc tcatctaata
     5941 ccatgaaaaa accttcgcca tatgcaattc ttatttttta cgtgatagta ttttacaaac
     6001 taaaatcccc cttttgtagc aacttatgta attacatttt agtgcttttt taaaggagtc
     6061 tcgaataaag caacatatat tttgttcaaa taatgttttt atttattttt taaatttata
     6121 tattacttca cccaaccaat tctcaactta aataactaaa ctactatcta ttcacagatt
     6181 aggcttattt cttacacatt agtttataat aaacactgtg aatctaaaca taaaaactgt
     6241 tattttaaag taattaccca tatattcgct ttgatactat ttattgaggt tatactcttt
     6301 atgtataata tattatttat aaaatacctc aaaatatatt attcataaaa tacctcaaac
     6361 tgaaaacttt ttcacgaata tttatttttc acctcccctt ttttatttca ccatgtaaat
     6421 cgtaccataa atatgcactt atatgcaaga aaaaaatcta ttaatcgaca gtaaataatt
     6481 agaaaaattc aaattatatt tatcaagtat attatataaa atatttccta tgaaaatata
     6541 aattaaatta atgttcagaa ttgtttttag atatgaaatc ttgatttttt tattacttta
     6601 cttatttgct caaatatatt tttgtatgca gtatataata atcaaattat acacttctta
     6661 taactgcatt gatttgaaaa taatattaat aattaataga ataaaaaatt taaattaaat
     6721 ttaaaaaaat ttgttaagt
//
LOCUS       DAEPUT010000140         6480 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.144, whole genome shotgun sequence.
ACCESSION   DAEPUT010000140 DAEPUT010000000
VERSION     DAEPUT010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6480
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.144"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..968
                     /locus_tag="KRL22_003672"
     CDS             <1..968
                     /locus_tag="KRL22_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1274096.1"
                     /translation="LNISKVNMFFDGGKFIGGKSIVFSIIGIIFLIILVSGIAYGYWV
                     TKCISNITSAVSDISKRSYLPVNIKGVFADIYNSLNILNEEIHKSDEIQNKTDIMREE
                     WISNITHDLKTPLSPIKGYAELLTDSSTNYSPEKVYKYASIMLKNIEYTNTLINDLKL
                     TYQLKNGIIPLNKNNYDLVRFLKELSIDILNYPEYESNIVEFKSNIDNINFDFDCTLL
                     KRAFSNLIVNAFTYGDKNTKVCVHITLNERIEIIISDNGKGMSREEASNLFNRYYRGS
                     NTKQKIEGTGLGLAITKQIIEVHGGNISVESIPGLGSSFYITFPI"
     gene            1187..3664
                     /locus_tag="KRL22_003673"
     CDS             1187..3664
                     /locus_tag="KRL22_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1274097.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMEKGMYGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMEGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGVTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            3679..4365
                     /locus_tag="KRL22_003674"
     CDS             3679..4365
                     /locus_tag="KRL22_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1274098.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVKENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            4639..5472
                     /locus_tag="KRL22_003675"
     CDS             4639..5472
                     /locus_tag="KRL22_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274099.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCMQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            5510..5971
                     /locus_tag="KRL22_003676"
     CDS             5510..5971
                     /locus_tag="KRL22_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH1274100.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLALGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            6002..6250
                     /locus_tag="KRL22_003677"
     CDS             6002..6250
                     /locus_tag="KRL22_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1274101.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVNDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
BASE COUNT         2495 a          693 c         1016 g         2276 t
ORIGIN      
        1 cattaaatat atctaaagtg aatatgtttt ttgatggagg taaatttata ggtggtaagt
       61 caattgtatt ttcaatcata gggattatat ttttaataat tttggtttct ggaattgctt
      121 atggttactg ggtaacaaag tgcatatcaa atattacatc tgctgttagc gatatttcaa
      181 aacgaagcta tcttccagtt aatattaaag gtgtttttgc tgatatatat aatagtttaa
      241 atattttaaa tgaagaaatt cataaaagtg atgagataca aaataaaact gatattatga
      301 gagaagagtg gatttcaaat ataactcatg atttaaaaac tccactttca ccaataaaag
      361 ggtatgcaga gcttcttaca gatagtagta ctaattattc acctgaaaaa gtatataaat
      421 atgcttcaat catgttaaag aatatagaat atacaaatac acttataaac gatttaaaat
      481 taacctatca attaaaaaat ggaataatcc ctttaaataa aaataattat gatttagtaa
      541 gattcttgaa agaattatcc attgatattt taaattatcc agaatatgaa tcaaatatag
      601 ttgaatttaa gagtaatata gataatatta actttgattt tgattgtaca ctattaaaac
      661 gagcttttag taatcttatt gtcaatgctt ttacatatgg agataaaaat actaaagttt
      721 gtgtacatat aacattaaat gaaagaattg aaatcattat atctgataat ggaaaaggga
      781 tgtcaagaga agaagcatca aatttgttta atcgttatta tagaggaagc aatacaaaac
      841 aaaaaataga aggaactggt ttaggactag caataacgaa gcaaattatt gaagttcatg
      901 gagggaatat atctgttgaa agtatacctg gattaggtag ctcattttat atcacctttc
      961 ctatttaatt aaggttaatt aaggttaaat aaaaaatata ttaaggttga tagattatta
     1021 tatttatata gtagtttatc aatctttttt atttaagggg tgatttgatt aaaaatatta
     1081 taaatagaat gataaaagta tggaggagtc tattagagat ttaatttaga ttaaagtata
     1141 aaaatattag attgaaatat cttagataaa gaaagaaggt gtaaatttga aaattatatt
     1201 aaagtatatt ttcacaaata ttaaagaacg aaaaattaga acagcagtta tgttattgtc
     1261 catagtttta tcaacagttt tactttttgt ttcattctca attggattat cttatgaaag
     1321 tgcacaaaga aaaatggaaa aaggtatgta tggtacagcg actatatctg tccaaagtaa
     1381 aaatccagat atattaacca atttagaaga catacctgat ttaaatgcta taaaatcaaa
     1441 ggttggtgta ttggaaagct ctgctattta taataaaggg ggatactatg aagaatttag
     1501 tcttatatca gcagacttaa gtcaactaaa taaaatcaat aagccacgat tagaaaatgg
     1561 cgatagtatt actgattttt ctggtgataa aattattctt ccaaatcgct ttacatcaaa
     1621 atataaaata aaaaaaggtg attctattac tttgcagatt tatggaaagt cttatacttt
     1681 tcaagttagt gatattgcat cttatgatac agtatttttg aggaacacaa gaggtgtaaa
     1741 tgcactgcta cccaaagaga ctctatcaaa aattataaat aaaggcagtg gatatacaag
     1801 agttcttata gagtcagaag aagaaattac agaaaatcta gtaaataaat tatccgaaga
     1861 actttctact gaaaaatata tggtatcaaa tactataaat gaaactaaga taatttcaga
     1921 tgctagacaa aagacaatgc ctttcttttt aataagtttt tttgcattaa cccttagtat
     1981 atttataata tacagcagtt ataaggttat tacattagaa cgtcttcctt ttattggaac
     2041 atttagaagt attggtgcca atgaaaaaac tgtaactcgt atattgatgc ttgaaagtat
     2101 attatacgga agtataggag gattaattgc tattcctatt ggtgtagttg ttttaaattt
     2161 aatgcttcat gggttaggaa attctctcga acaaggaata tcaattccag tagtaatatc
     2221 acccattgga gtgattatat ctgttatagt agcaataatc gtttcttcat ttagtgcata
     2281 tatacctgtt aaaaaagcta gccatttgcc gataaaaaat attgtactag gaacagtaga
     2341 agaaaagaat gtttcaaatc gttctatact ttttatagga agtataatgt ttattttatc
     2401 tattttactt ccaagaatat cccctgaaaa tacattgtat ctagctggtg gattttcatt
     2461 actaggatta attgtagcta ctattgtgtt gattcctctt attactgata tcatgtctat
     2521 agtttttgag tttgtttata aaaatatttt agggaatgag ggtaaattag ctgctagaaa
     2581 tatgaaaaat aacaaaaata taatacagaa tatcacttta ctatttataa gtatttctgc
     2641 agttattgca ataagtgttg ttggtaactt tgtcaaaact tatataacag atgtgtttcg
     2701 tgacgcagaa ttacaaggtt ttgcagatgg aaagatgaat gaagagttta ttgaagatgt
     2761 tagacatatg gaaggaatta aaaaaatatt acctctttat gttatgaata atgagatttc
     2821 tggtaatggt gtaacattat caagactaga gggtacagat aatataaaac tatataactc
     2881 tatgtttgga atcaattata caaattttga gataaaaaaa caagtaatag aagcttttaa
     2941 tgataaacgt tctgttattt tgaatgaaga tactctaaaa aaagtaggct tatctatagg
     3001 agatacaata actctatcta atgataagta tgatttttct tataaaatag taggtagttt
     3061 taaatcccgt gcaaatgatg tagaagctgt tataccatca cattatgcag ttaatgattt
     3121 tgataaaact aattatggtt ttttagtata tacagcagtc aatccagatg ctgttatgat
     3181 tcagataaga tatttatttg gagatacata taattggagt cgtacagttg aagaatttaa
     3241 taatgattct ttaaatacta taagtagttt tttgtctcct atgaataaga tgacctattt
     3301 catttttctt cttgctacag taggtattat taataatcta ctgattaatt atattcaaaa
     3361 aagacgttct atagctatgt ataaatctat aggactaagt aataaacaaa atataaaagt
     3421 aacattgatt gaaggggtta cttcaggttt acttggagct gttattggta ttgtgatatc
     3481 tatacttgag attcaaacta tctttatagt tgcaggacca aaaatttcaa tgaaaccaga
     3541 tttagatttt aaaacattta ttattgttgg gttattggga attatagtaa ctttaatagg
     3601 ttcgatagtg cctattataa aagggaagaa aatgaaactg atagaagaaa ttaagtttga
     3661 ataattatgg aggttaatat gaaaattaca cataatagtt tagctgtaga agcaaaaaat
     3721 attatcaaag aatataaaat tggaaataca acaactcgag tgttaaaaga ggtatcttta
     3781 caagtaatga aaggtgaatt tgtttctatc atgggtcaat ctggttctgg taaaagtact
     3841 cttttatata ttttaggtgg tttagatact ccaacgagcg gaaaagtgta tatgaatgga
     3901 gctgatatat cacattttaa tgatgagaaa atgagcataa tacgtcgtag aaatatagga
     3961 ttcgtatttc aattttataa cttaatacca aatttaaatg tgaaggaaaa tataatgctt
     4021 cctttgttat tagatggtaa aaatttaaaa gattataaaa atcaattaga tgaaatctta
     4081 gatatagttg gtttaactga tagacgtaaa catacaccac gagagttatc tggtggtcag
     4141 caacaacgtg ttgctatagc tcgagcttta attggaaaac cagagatttt atttgctgat
     4201 gagcctactg gaaatttaga tagtaaaaca gggatagaaa taatagattt actgaataaa
     4261 ataaacagag acaatggaca aactataatt atggtaactc actcaccaga agcagccaaa
     4321 agtagtagtc gtactattac agtttcagat ggtttaattg tataaggact aattattgta
     4381 tttgagataa gcatttttaa ttatataaat tagacatatg taaagtggat ataagttaaa
     4441 tactataaat gtgctataat attaaaataa cagataaaag tactatattt tttattgatt
     4501 attttaattt tatttgttta ttaaatatct aatgagtatt catactatct ctattattaa
     4561 aagcagttaa tgatatatag agataatatg gattcttctt actttaataa atattcacga
     4621 taggacagga tataatatat gttaaaaaaa gaaagtattc attttataaa taaaaatagg
     4681 tcacttatag tttgtgaaga caattttgtt tatctcttgc cttgtatgca attaagaaat
     4741 tggatatcga attttactat atcgtttcca aatcaaacaa taatttctga taattacacg
     4801 attattcctc atggaagtgt aactttggtg tttttttatg atgccacagg gttacatagt
     4861 ctattatttg gtccaactac taaaccaaaa acagtaggaa atattgctaa tagatgtgat
     4921 gttatactaa ttatagaatt tcaacctgct ggttttttcc cgcttatagg tatacagcaa
     4981 agtgaactta ttgataaagt tgttccattt tctataatta atacttcatt agatttagaa
     5041 attaaaaaaa tatttaatga atctttatct atagataaat tgattttaaa gttggaagaa
     5101 ttattgattt ctaatattaa aattgaatac tcatatgagt ttattttggc aattcagttg
     5161 attattcaaa actctggaaa tatatcttca caagaaattt ctaaaaaagt attttatagt
     5221 tctaggcatt taaacagact ctttaatcag tacctagggt tgagtatgaa gtcattttct
     5281 cgtttggtac gtattaataa atctataaaa cttctaaaca ataataaaac ttcattgatg
     5341 tctatatgta atgaattagg attctatgat ataccacatt ttattaaaga ttttaaaatt
     5401 gtctgtggaa taactcctca aaaataccga gctaatatgt ctgattttta cagtgaaatt
     5461 gcaaaatttt aagttataat acttataaca aagaaaggat agtgataaga tgaaatttgg
     5521 aggagtattg ctaattgtca aagacataaa taaatcaaaa aagttttatg aagatgttat
     5581 ggagcaaaaa atcacattag ctttaggaga acatgtatca tttgaaaatg gatttggatt
     5641 acaaagtaat tataaagcta taattggata tgatttacca atatatcaac aatcaaataa
     5701 ctttcagttg tattttgagg ttaatgacat caaacaatgg gaaagtaaga taaatagaat
     5761 aggaaatatt gaatttttgc attatataaa agaataccca tggggtcaaa gaacttttag
     5821 gttttatgat tttgataaaa atattataga aatttcagaa agtatggaaa gcgtcataaa
     5881 gaggctttta aaacaaggtt tagctttaga agaaatttca aaacgcacta tgtatccagt
     5941 tgaatttatt acacaatttc aacaattata aaatattaaa atatataatt ttttctttat
     6001 attgcaaaaa acaaaggctt ggggcataat agaaccagaa aaacctgaat ctcaacagca
     6061 aatggctcat atggatttcg ctgttaatga tttagaagaa gcagttcaat atgcaattca
     6121 ttgtggagct acaatcgcag aggagcaatt tactgatgac tggagagtta tgattgaccc
     6181 agctggacac cctttttgct tatgtcagat gaaatcaatt atggaaagta gccatttttc
     6241 attgttatag accaaaatat tgtttattaa ttacaaaaaa gcacaacagt atataccgtt
     6301 gtgcttttac ttattataca tgaatacact aaaaaatata aatagtagag ctttatcaat
     6361 aatgataatt tttaaaaaat agtatttttt tattgaataa tttcttagat attttaaagt
     6421 atataaattt tgcatatatg aattggacat tatcaaatgt gttataatat taaaacaaca
//
LOCUS       DAEPUT010000141         6380 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.145, whole genome shotgun sequence.
ACCESSION   DAEPUT010000141 DAEPUT010000000
VERSION     DAEPUT010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6380
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.145"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            300..1244
                     /locus_tag="KRL22_003678"
     CDS             300..1244
                     /locus_tag="KRL22_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HBH1274102.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1266..1892
                     /locus_tag="KRL22_003679"
     CDS             1266..1892
                     /locus_tag="KRL22_003679"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBH1274103.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1926..2975
                     /gene="hisC"
                     /locus_tag="KRL22_003680"
     CDS             1926..2975
                     /gene="hisC"
                     /locus_tag="KRL22_003680"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH1274104.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2978..3556
                     /gene="hisB"
                     /locus_tag="KRL22_003681"
     CDS             2978..3556
                     /gene="hisB"
                     /locus_tag="KRL22_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HBH1274105.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3558..4163
                     /gene="hisH"
                     /locus_tag="KRL22_003682"
     CDS             3558..4163
                     /gene="hisH"
                     /locus_tag="KRL22_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBH1274106.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4160..4882
                     /gene="hisA"
                     /locus_tag="KRL22_003683"
     CDS             4160..4882
                     /gene="hisA"
                     /locus_tag="KRL22_003683"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBH1274107.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4864..5622
                     /gene="hisF"
                     /locus_tag="KRL22_003684"
     CDS             4864..5622
                     /gene="hisF"
                     /locus_tag="KRL22_003684"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBH1274108.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            5650..6318
                     /locus_tag="KRL22_003685"
     CDS             5650..6318
                     /locus_tag="KRL22_003685"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBH1274109.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVNKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2608 a          537 c         1261 g         1974 t
ORIGIN      
        1 aaaaactgta aatttagaat attaataaaa attatttggg aggaaattat catggtgaga
       61 ttaaatatag taaaattaaa tacaaaatta aatcatcacc atcatcatag attaaaggga
      121 ttgtaatatg aaattaattc atagacacaa gccctgtttt tagtgtaatt ggtcttgtat
      181 ctatgatggg aagtaatttt aagagaaaat tatagccata taggtataaa gcctatgtgg
      241 cttttttatt gttttaaatt tgcaaatata agagtaaatt tgatgaagag ggtgagaatg
      301 tgaaattttt gaggattgaa gatgaggtta tttattctaa aaaaagatat aaattaaaaa
      361 gggaaataga taaacttttt ttggatgaag aatattttca aatagaacca caattatttg
      421 aagaatatga tgaatttaca actataaata ataaaattcc agaagaatct atggtaaagg
      481 ttgtaaatgg aaaagtaatg gtacttagag ctgatataac tacaagtata ataaaaagcc
      541 ttgtaccaag atgggaagat ggtttaaagc ttaagctttt ttataattca tcaatatata
      601 aaaataaaaa tacagttgga ataaaagaga taagacaaat aggttgtgag tatctaggag
      661 aagcctctgt agaagcagat agagaagtag tgaaattagc tcttaagata cttgaaaaat
      721 acaataataa ttttattcta gaggttggga gtagcaagta tattcatggt ttgttagaag
      781 aattaaattt aaataagaat tgtgaaaatc aaattaaaaa tttactatat acgaagaaca
      841 ctcatgaatt aaaagtatat attgaagaat taaaaattaa gcgtgaagta aaagagttat
      901 tatcaaatat tttaagttta caagggaatt tatataatgt tattgaaaaa tcaaacaagt
      961 tctattgtaa taataagatg aagcaagctc ttgaagaatt aaagcaagta aataatttga
     1021 ttgaggaatg taatttttta gataaggcta gatttgattt atcaatgatt actatgcttg
     1081 actattatga aggaattatg tttagaggat actacccaaa ctcatataaa gaaattctta
     1141 gtggtggaag atatgattct ttaactaaag agtatggaaa agaaattcca gccattggat
     1201 ttacactaag tgttgatgag ttaatgaagt atgtatataa gtaaagttta gaaggaggga
     1261 ttgctttgga ttatttgact atagcactag caaaaggacg aattgaaggg gaatcattta
     1321 aaaaatttaa aaaaatgggt ctaggagata gtatagacac agatacgaga aaactaattt
     1381 ttaaagatga agaaaataaa attatatata tacatgtaaa gccatcagat gtagttacat
     1441 atgttgaaaa aggagtcgct gacctcggta tagcaggtaa agatactatt ttagagaatg
     1501 agacagatgt atatgaaata tatgatttag gttttggaaa atgtaaattt gctgtagcag
     1561 gattaaaggg agatagcata tatagagaag atgaatattt aaaagtggca acaaagtatc
     1621 ccaatatagc aaaaaagtat tttaaagaga aaggtcaaaa aattgaaata ataaaattaa
     1681 atggttctgt agaactagct ccaatagtag ggttgtcaga tgtaattgta gatatagttg
     1741 agactggcaa tacacttaaa gcaaatggtc ttgaaatatt agaagacata tgtaatataa
     1801 gtgctagaat tatatcaaat agagctagct atagatttaa atatgaacaa attcagaata
     1861 taattcgttt atttgaagaa cttgataatt aaaatataat tgagctttat aaggagggat
     1921 ttaagttgag agaaaaagaa agcataagag agttaagggg atatgaacca aatcacgtaa
     1981 actgtaaagt aaaacttgat gcaaatgaag gaagtaagag gttgtttaaa taccttatta
     2041 aagaaatttc agatagtgat atagatttaa atttatatcc tgaagattct tatagtgatt
     2101 tgaaagaatc tataatagat tacataaata tttctggagt aaataagaaa aatcttctag
     2161 taggaaacgg ttcaagtgaa ataattgatt taataataca tacttttgta gataaagatg
     2221 aagtaatatt gagtttctct ccaagtttta gtatgtattc tatatatagt cagataaatg
     2281 ggtctaaatt tataggtgtt gaaagtgatg aaaatttagt tataaatata gataatgtga
     2341 ttgaaaaagt aaaggagaat aatcctaaaa tagtaattgt atgtaaccct aataatccaa
     2401 ctggaacaat attaaagagg gaagagataa taaagctttt agattcaact aatagtctag
     2461 tggttttaga tgaagcatat atggattttg gagaagaaag catgttaagt gatgttttta
     2521 agtatgataa tctaatagtt cttagaactt tatcaaaggc atttggattg gctggaataa
     2581 gaacaggata tatgttatct aatagtagtt taataaattc tgttgagaaa gtaagacctc
     2641 catataattt aaattcatta tcagacttta ttgctacaag agcacttaga aataaagatg
     2701 tggtaaaggc ttatataaag gaagtaaaag aggaaagaga agttttatat gaagaaatga
     2761 ttggtatggg aattaaagca tacaaatcac aagcaaattt tatattattt tattctgaaa
     2821 tcgaaaattt atcacaaaaa cttattgata gaggagtttt aataagaaaa tttggtggaa
     2881 agttagaaaa ttattacaga gttacaattg gtgataaaga agaaaattct atgtttgttg
     2941 gagctataag agatattttg aaaaaggaga aataggtatg agaatttgga aggtagaaag
     3001 aaatactctt gaaacacaga ttttagtaga attaaatatt gatggttctg gtaaagctga
     3061 aatagatact ggaataggat ttttagacca tatgcttacc ttaatgtcat ttcatggcaa
     3121 gttcgattta aaagtgattt gtaagggtga tacatatgta gatgaccacc atagtgtaga
     3181 agatataggt atagctatag gtgaagcatt taaaaatgct ctaggtgaca aaaaaggaat
     3241 acgaagatat tctaatatct atatacctat ggatgaatct ctatcaatgg tagcaataga
     3301 tataagcaat agaccttatc ttgtatttaa tgctaaattt gatacccaaa tgattggtag
     3361 tatgagtact caatgcttta aagaattttt tagagctttt gtaaatgaat cgagagtaac
     3421 attacatatc aatctcttat atggggaaaa tgaccatcat aagatagaaa gtatttttaa
     3481 agcatttgca agagctttaa aagagggtag tgaaatagtt tctaatgaga tagcatcttc
     3541 aaagggggtt ttgtagaatg aatataatag tagactatgg tcttggaaat atagattctg
     3601 tgtctagggg ttttagaaaa gctggaatag aaactaaaat ttctagtgat atagatgaaa
     3661 taaaacaggc agattcactt atacttccag gtgttggagc ttttagagat tctataagtg
     3721 ccttagataa actaggattg ataccaataa taaaggagca tgtttctaag ggtaaattta
     3781 tgataggtat atgtctagga atgcaattac tttatgaaaa aagttatgag tatggagaat
     3841 atgaaggatt aggacttata aaaggaagta ttgataaact ggatataagt ttaaaagtgc
     3901 cacatatggg atggaataat ctaaaattta ataaggcaaa tgatgatata cttaaatata
     3961 taaatgaaga tgattatgta tacttcgttc actcatatta tgcaaattca tcaaatgaag
     4021 aactaattgc attttcagaa tatgaaaaga aaatccctgc tattgttaga aaaggcaatg
     4081 tatatggtat acaatttcat cctgaaaaaa gtggagaagt agggttaaat atattaagag
     4141 catatgggga gatgataaaa tgataatatt tccagcaata gatataaaag ataataagtg
     4201 tgtaagactc acacaaggag aatttgacaa agtaaatgta tattatgata atccattaga
     4261 agtagcatat aaatggaaaa atgaaggagc agaatatata catatagtag atttaaatgg
     4321 tgctagaagt gaatttggtg taaatacaaa aataattgag gacatagcaa acaatataga
     4381 tatacctatt caagttggcg gtggagttag ggataaggaa aaagtcaaaa gtttaataaa
     4441 tgctggtgtt actagagtaa tattaggcag tatagcgatt gaaaatttga atttagttga
     4501 agaattggtc aatgaatata aagagaaaat tgtagtttct atagatgcta aagatggaaa
     4561 agtagcagtt aggggatggg aagttgtaag caatgtagac tcattaacat tatgtaaaca
     4621 acttgaaaag ataggtgtac aaactattgt ttatacagat atatcaaaag atgggatgtt
     4681 gcaaggtcca aattttgaca tatatgaaag aatagcaaag gaaacatcac taaatgttat
     4741 tgcttctgga ggtgtaactt ctatagaaga cgtaaaaaga ctaaaagcta tgaacttata
     4801 tggtgcaata ataggtaaag cgctttatga taaaaagata gactttaagg aggcacaaca
     4861 attatgctta ctaggagaat aataccttgt ctagatgtga gaaatggaag agttgtaaag
     4921 gggaaaaaat ttaaagatat agtagatgtt gatagtccag aagtacttgg aaaattttat
     4981 agtgattgtg gtgcagatga acttgtattc tatgatataa ctgcatcaaa tgaagagaga
     5041 aagacatctt tagaatttgt gacaaaagtt gcagaaaata taaatatacc attttgtgtt
     5101 ggtggaggag taaataaatt agaagatttc actgatattt taagaaaagg tgctgataaa
     5161 gtttctataa attcatcagc agtcaaaaat cctgaattaa taagggaagc ttcattaaaa
     5221 tttggagcac aatgtgttgt tttatcgata gatgcaaaga aaaatgaaga gggttcatgg
     5281 agcgtatacg taaaaggtgg aagagaaaaa actaatctgg atgcaattga atgggctgtt
     5341 aaaggtgtag aacttggagc aggagaaatc gttgtaaata gtatggatga agatggaatg
     5401 aaaaatggat atgatataga attattatca aagataactt ctttagtaaa tgtacctgtt
     5461 atagcatctg gaggcgctgg aaaaaaggaa gatttttatg aggcggttaa taaatccaat
     5521 gtagatggaa ttttagcagc atctgttttt cattttggcg agataaaaat aaacgattta
     5581 aagaaatatt taaaagacat gggtgtagaa gtaagattat aagttaaata ctaaaaggag
     5641 attagaaata tggataataa gtgtaacaat gtatacagtg atgaagtaga gaaatttata
     5701 agaagtataa agtttgatga taaagggtta gtccctgttg ttgttcaaga ggtagttaac
     5761 aaagatgtac tgatgttagc atatatgaat aaagatgcta taaagaaaac cttaaaagat
     5821 aaagtagctt gctattttag tagaagtaga caagaacttt gggttaaagg tgagacatct
     5881 ggtaatactc aaaaagtagt taagatgtct tatgattgtg atgtagatac tatactactt
     5941 tttgttgaac aaactggtgt agcttgtcat acaggcaatt attcttgttt ttacagagac
     6001 ttgtttgatg atagttcaaa aatggagctt gaagtacaaa caaatatatt gaaagaatta
     6061 tatgatttaa tcaatgaaag aaaaaataat ccagttgaag gttcttatac taattatctt
     6121 tttgaaaaag gaatagataa gattcttaaa aaagtaggtg aagagagtag tgaggtaatt
     6181 atagcatcaa aaaatactga taaaagtgaa cttatttacg aaattagcga tttagtatat
     6241 catacattgg ttttaatgat agaaaaaggt gttgaaattg atgaaataaa aaaagaatta
     6301 cttaaaagaa gaaaatagaa taagatagat taatgggtaa taagaaaata taccactttt
     6361 aataaaaagt ggtatatttt
//
LOCUS       DAEPUT010000142         6221 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.146, whole genome shotgun sequence.
ACCESSION   DAEPUT010000142 DAEPUT010000000
VERSION     DAEPUT010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6221
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.146"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..716)
                     /locus_tag="KRL22_003686"
     CDS             complement(<1..716)
                     /locus_tag="KRL22_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBH1274110.1"
                     /translation="MNAINWKKLLLPNIPYLLFVYLFDKVGQAVHLAPGADLSGKVLS
                     LGEGFSAAFANPLPSLAPMDLLIGILGAVLIRLIVYVKGKNAKKYRKGVEYGSARWGT
                     AEDIKPYTDPVFQNNVLLTQTERLSMNSRPKQPKYARNKNILVIGGSGSGKTRFFVKP
                     NLMQMHSSYVVTDPKGTVLVECGKLLQRGGYRIKVLNTINFKKSMKYNPFAYLRSEKD
                     ILKLVNTLIANTKGDGEKAG"
     gene            complement(713..1195)
                     /locus_tag="KRL22_003687"
     CDS             complement(713..1195)
                     /locus_tag="KRL22_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBH1274111.1"
                     /translation="MQEETNEKTIALYIKTGKLTAQQLQKAMKALLAQMKKQHDKQKI
                     PHGKQTLKQLMKQNAGVSNIEITKDNIKAFESTAKKYGIDFALKKDSTETPPRYLVFF
                     KGRDADALTAAFKEFSAKKLTQEQNPSIRKLIVSLKEKAAALNAQRDKVKNKDRGIAR
                     "
     gene            complement(1290..1508)
                     /locus_tag="KRL22_003688"
     CDS             complement(1290..1508)
                     /locus_tag="KRL22_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBH1274112.1"
                     /translation="MTQKTGALIFDETADRYDIRFDVNDYYGGLHCGDCMEVFVRGKW
                     KPTRMEYGDNWYLVGIRAADLSGLRVRI"
     gene            complement(1533..2507)
                     /locus_tag="KRL22_003689"
     CDS             complement(1533..2507)
                     /locus_tag="KRL22_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274113.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKELSLKAKGLLSQMLSLPEDWD
                     YTLAGLSLINRESIDAIRTAVWELEKAGYITRRQGRDEKGKMTAIEYTIYEQPQPPAL
                     DCPILENPTADKPILENPTPDNPTSENPTQLNKELLKTNLPNKEKLNTDISSTHSIPF
                     HSLNPSPLEDAAQPPERKRKETTDAYSVYEEIIKDNIEYDYLIQDRYLDRDRIEEILA
                     LILETVCTKRRTIRIAGDDHPAELVKAKFMKLNSEHIRFVLDCMQENTTKIRNIKQYM
                     KAALFNAPSTIGSYYTSLVSHDMADGTFYGKPKKSGIPDYTCDEGESL"
     gene            3006..3371
                     /locus_tag="KRL22_003690"
     CDS             3006..3371
                     /locus_tag="KRL22_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274114.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3394..5781
                     /gene="cadA"
                     /locus_tag="KRL22_003691"
     CDS             3394..5781
                     /gene="cadA"
                     /locus_tag="KRL22_003691"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBH1274115.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
BASE COUNT         1931 a         1019 c         1323 g         1948 t
ORIGIN      
        1 tccccggctt tttccccgtc ccctttggtg ttggcaatca aagtgtttac cagtttcaaa
       61 atgtctttct cgctgcggag ataggcaaag ggattgtatt tcatgctttt tttgaagtta
      121 atcgtgttca gcacttttat ccggtagccg ccccgctgta agagcttccc gcactcgact
      181 aaaaccgtac ctttcgggtc ggttacaacg tagcttgagt gcatttgcat taaattcggc
      241 ttcacaaaaa atctcgtctt gccgctgcca cttcccccga taacaaggat atttttattc
      301 cttgcatact tcggctgctt cgggcggctg ttcatgctaa gccgttccgt ctgtgtcagc
      361 agcacgttat tttgaaatac cgggtcggtg tagggcttaa tatcttcggc agtcccccaa
      421 cgggcagagc cgtattccac acctttgcga tatttctttg cgttcttgcc tttgacatag
      481 acaatcagcc ggataagtac cgcgcctaaa attcctatca gtaaatccat aggggcaagg
      541 ctcggaagcg ggtttgcaaa ggcagcggaa aagccctccc caagcgacag caccttgccg
      601 gacaggtcag cccccggcgc aaggtgtacc gcctgcccga ctttatcaaa gagatacaca
      661 aagagcagat agggaatgtt gggaagcagc agctttttcc agttgatagc gttcatcttg
      721 caatccccct gtctttgttt tttactttgt cccgctgtgc gttcagagcc gccgcctttt
      781 ctttgaggga aacaatcagt ttgcggatag agggattttg ttcctgcgtc agcttctttg
      841 cggaaaactc cttgaaagct gcggtcagtg cgtccgcgtc ccgtcccttg aaaaacacca
      901 aatagcgggg cggggtttcg gtgctgtctt tctttaaggc aaagtcaatc ccgtattttt
      961 tcgccgtact ctcaaaggct ttgatattgt cctttgtgat ttcaatgttg gaaacgcccg
     1021 cgttctgctt cataagctgc tttagagtct gctttccatg cgggattttc tgtttgtcat
     1081 gctgcttttt catctgtgca agcagggctt tcatagcctt ttggagctgc tgcgccgtca
     1141 gctttccggt cttgatgtaa agggctatgg tcttttcgtt ggtttcctcc tgcaatgggt
     1201 ttcctccttt cgtgttctat ggtggtatgc ccgccgccgg gaagtggggc gggcatgaaa
     1261 aaaagagcgt ccgttttcac gacgccctgt taaatccgta cccgcagccc ggaaaggtct
     1321 gccgcccgaa tacccacaag ataccagttg tccccatact ccatacgggt aggcttccat
     1381 ttgccccgca caaagacctc catgcagtcg ccgcaatgca agcccccgta atagtcgttt
     1441 acgtcaaagc gaatgtcgta gcggtcagcg gtttcatcaa aaatcaaagc tcctgttttc
     1501 tgtgtcatta taaaatcctc ctttgggttg gtttacaggc tttcgccctc gtcgcaggtg
     1561 taatcgggta tgccggattt tttcggtttc ccataaaatg tgccgtctgc catatcgtga
     1621 gatacaaggg acgtgtaata gctgccaatc gtagacgggg cattgaaaag ggcagctttc
     1681 atgtactgct tgatgttgcg gattttggtg gtgttttcct gcatacagtc cagtacaaag
     1741 cggatatgtt cgctgttcag tttcataaat tttgctttta caagctctgc cgggtggtcg
     1801 tccccggcga tacggattgt tcttcgtttg gtgcagacgg tttcaagaat aagggcaagg
     1861 atttcctcta tcctgtccct gtcaaggtat ctgtcctgta tcagatagtc gtactcgata
     1921 ttgtccttga tgatttcctc atacacgcta tatgcgtctg tcgtttcctt tcgcttccgt
     1981 tccggcggct gtgccgcgtc ctctaaggga gagggattta gggaatggaa aggaatggaa
     2041 tgggtacttg atatatctgt atttaatttt tctttgtttg gtaagttagt ctttaatagt
     2101 tctttattta attgcgttgg attttccgac gtcgggttat ccggtgtcgg attttccaat
     2161 atcggcttat ccgctgttgg attttccaat atcggacaat ccaatgccgg gggctgtggc
     2221 tgttcgtaaa tggtgtactc gatagcggtc attttgcctt tctcgtcgcg tccctgccgc
     2281 cttgtgatat atccggcttt ttcaagctcc catacagcgg tgcggatagc gtcgatactt
     2341 tcccggttga taagggacag ccctgcaagg gtgtagtccc aatcttcggg aagtgagagc
     2401 atttgcgata acaagccctt tgcctttagg gaaagttcct tgttgcgtaa atggtggttg
     2461 ctcataaccg tataaccttt gttcttttcc acgcgaaaaa ctgccatagc ttcgtcactc
     2521 cttttcgttg gatttgttac gcagtagaaa cgcggtttgg agggaaaagg tatcaaccct
     2581 tgtctttctt atctccgcgc tctaagagcc acataaatca agacttcttt tgcccttact
     2641 gcgtaacatg agggcataaa aaaagcagcg ttcctgttct cctgtgtagg agtaagaaac
     2701 gccgccttat aggtggtgct tattttattt tttcttatcg acgtgccgcg caaggtggtg
     2761 tagcggtcta tccggcagct tcgcaggtgc ttttgcatat caaggcgcaa tccgttaaaa
     2821 gtagtaaatg agtagtaaaa tcaatctgca aacctgcgaa tatgcccgta aatcaagcat
     2881 ttttcaagac aatcaactaa tttaaagagt aaattaataa aaattattgt tgcaaattta
     2941 gaaatgataa catataatga acatatgaac agttattcat atattaaaat aatggaggat
     3001 taaaaatgag agaagagata aatgattgta attgtaatat agtacatgaa gaaatagtaa
     3061 cagaggctaa atcaactatg ccagatgaag aaatgttata tgatttagca gaattattta
     3121 aagtatttgg ggatactact agagtaaaga tattatatgc attatttgca aatgaaatgt
     3181 gtgtatgtga tatagcgagt ttattaaata tgactcattc tgcaatatct catcaactta
     3241 gagtattaaa gcaggctaga ttagtaaagt ttagaagaga aggaaaaaca gtgtattact
     3301 cattagatga tagtcatata agtcagatat ttgattgtgg attaaatcat attagagaga
     3361 cttataaatg ataaatgaga ggagtgaata tatatggaag caaataattc aattaaaaaa
     3421 gaatttatac taggaggatt aaattgtgct cactgtgcag aggagattaa taataaagtt
     3481 tctaaactac aagaagttaa atcttccaat ttaaatttta taaataaaaa acttacagta
     3541 aatataaagg aaagttttaa tgaggatact actatagaaa agataataga tataatagat
     3601 tcaacagagc caggtcttga tatacaaata agttctaaag aaaatgcagc tagtaaaaca
     3661 tcaattaaaa aagagcttat attaggagga ttaaactgtg ctcattgtgc agaagagatt
     3721 aataacaaag tttctaaatt aaaagaagtt gaatcttcta atttaaactt tgtaaataaa
     3781 aaacttacag taaatataag taataacttt gaagaggatg atgttataaa taaaataaaa
     3841 gaaataataa attcaacaga gccagggctt gatatacaag tagggtctac tgacaaagta
     3901 aaagggagaa ctactgaaaa atcaggagct gtaaatgata caaataagaa agaattaatt
     3961 ccacttataa ttggagcact tgtatatata tttggtatat atcaaacagc tacaggttat
     4021 gaaagtcagt ttagcaatat agtatttata gttgcctatg taatagtagg tggtgatgtg
     4081 cttttaagag caataagaaa tatatcaaaa ggaagagtat ttgatgagaa ctttttgatg
     4141 gctctagcaa cagtaggagc attagcaata ggggagttat cagaagcagt aggggttatg
     4201 cttttctata aagtaggaga gtatttacaa ggtgttgcag ttggtaaatc cagaaagtct
     4261 ataacttcac ttatgcaaat aagaccagac tatgcaaatc taaaagttaa ttctgaagtt
     4321 aaggtggtgt caccagaaga ggtaaatgta ggtgatataa tagtagtaaa acctggtgaa
     4381 aaagtaccat tagatggtgt agtagtagat ggagtttcta tgttagatac ttctgcactc
     4441 acaggagagt cagtgctgag agaagttgaa aaaggagatg aaatcttatc aggtgttata
     4501 aataaaaatg ctttattgag tattgaagtt acaaagagtt ttggagaatc aacagtttct
     4561 aagattcttg accttgttga aaattctagc attaaaaaat caaagacaga aaactttata
     4621 tctaagtttt caagatacta tactccaata gtagtaatag ctgctttatt aatagcattt
     4681 gtgccaccac ttgtaatctc aggtgaggta tttagtgatt ggttatatag aggattgata
     4741 ttcttagtcg tttcttgccc ttgtgcatta gttttatcaa taccacttag tttctttagt
     4801 ggaattgggt ttgcatctaa aaatggtatc cttattaaag gaagtaacta tttagaagct
     4861 ttaagaagtg tagatacagt agtatttgat aaaacaggaa cacttactaa aggtgtgttc
     4921 aatgtaacta agttaaatcc tgaaggtata tcagaagaag aattattaga atatgcagct
     4981 attgcggagg taaattcaaa tcatccaata gcaaagtcca tattaagtta ctataataaa
     5041 aaaattgatt tagatacaat agacagttat gaggaaatag cagcttatgg aattagagta
     5101 aagcataatg gcaattttat attagcaggt aatgagaaac ttatgaaaaa agaaaatata
     5161 tcttattcat cagctaaaga agtaggcaca gtagtctata ttgctgttga taaagtatat
     5221 agaggttata tagttatctc tgatgaagta aaagaagata gtaaaaatgc cataagaagc
     5281 ttaaaagaaa taggggtaaa agaagttgta atgttaactg gagataatga gaaagtagca
     5341 aaaaatattg ctcaagaatt agaattggat acagtttact caaatttact tcctaatgaa
     5401 aaggtagata gattagaaga tttatatgaa ggaagaactg aaaaagagaa aatagcgttt
     5461 gtaggtgatg gaataaatga tgctccagta ttagctcgtg ctgatgttgg tatagctatg
     5521 ggaggcttag gttcagatgc tgctattgaa gctgcagatg tagtgcttat gacagatgag
     5581 cctagcaaga tatctaaagc aattgaaata gcaaacaaga ctaataagat agtgtggcaa
     5641 aacataatat ttgctctagg agtaaaaatt atagttatga tactaggtgc tggaggagta
     5701 gctactatgt gggaagctat atttgctgat gtaggtgtgg cacttatagc agtagtaaat
     5761 gctatgagag ctatgagata agggataaat gtaaatccat actatttaaa aaacttataa
     5821 ttatatattg aagtatgtaa taatgaaagg tatcaataag tttcttttaa ctttattggt
     5881 acctttttat tggagcgctt tgcatatata aatttatatt cattatccat tatgtttatt
     5941 taatgtattt atttagtgta gagcttttat attgtaattt taaaatttag acatagaagg
     6001 tttattaata agtttatatt aagtttaaat tagattcata aaaattataa tacttatgat
     6061 tgtatatata ttatattaat agttgtaatt tttacaacaa aatgtgtgtg ttaaaatact
     6121 ctaaaccaac agtatgactg ccattcaata aattatgtaa tataagaaag taaatatttt
     6181 taaaaaataa ttttaaaaag tattgacgaa ttatttttaa g
//
LOCUS       DAEPUT010000143         6221 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.147, whole genome shotgun sequence.
ACCESSION   DAEPUT010000143 DAEPUT010000000
VERSION     DAEPUT010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6221
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.147"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(341..838)
                     /locus_tag="KRL22_003692"
                     /pseudo
     CDS             complement(341..838)
                     /locus_tag="KRL22_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
     gene            complement(944..1306)
                     /locus_tag="KRL22_003693"
     CDS             complement(944..1306)
                     /locus_tag="KRL22_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274116.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            complement(1324..1938)
                     /locus_tag="KRL22_003694"
     CDS             complement(1324..1938)
                     /locus_tag="KRL22_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH1274117.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            2534..4669
                     /gene="rnr"
                     /locus_tag="KRL22_003695"
     CDS             2534..4669
                     /gene="rnr"
                     /locus_tag="KRL22_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBH1274118.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            5418..5909
                     /locus_tag="KRL22_003696"
     CDS             5418..5909
                     /locus_tag="KRL22_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBH1274119.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDREFPVMLITANDVKELSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASDDGLAVIF
                     FIM"
BASE COUNT         2442 a          725 c          906 g         2148 t
ORIGIN      
        1 ttattaaatt ttatataagc tattgaattt tatgcagatt attgtatttc atttagatta
       61 taaaacttta tgtagagtta atgaatttaa catatattat tagttatatt agtgctttta
      121 ttttaatgag tctaataata attctaatag aaactgaaat agataagtaa gttttaagct
      181 aaaatcaatt tatataaatt gataataatc taatagaaat taaaatacca gttaactaaa
      241 atatatatta agataaagtg cagaaaatat tctaataaca attaagctaa tcatcaatta
      301 aatgtagcat ttaattaatg attagctata gtcaacctaa ttaattagaa taacttcctt
      361 ttagtgtaaa tgtatctaaa acatgccctt caatagcttt gaaaaattca ttcatataga
      421 atcctttttc aaggtcaagg atagtatcaa gtgcaaatac atgtatttca tagacatgag
      481 gtctgtctgg aggagccatt ccaccatata cactggcctc taatctgtca agacctccta
      541 gtttaccatg ctaactagta gtcccttgta caaaatcagt agctgttaca ctttcatttt
      601 catttaactc atcttttgtt atatttacag ctaaccaatg tatccatgca aacccacata
      661 caggaacaga gtctttatct tctaaaaata cagcaaagga tactgtattc tttggagcat
      721 cttcaaactt tagaggtagt gaataggtag gcataccacc ttcattgaac tgagttcccc
      781 ttttaccgta tttatcttct ataacaccat ttactatacc tgtactagtt actttcataa
      841 taatttacct cctattataa taaattaata gaatatatct ataatttaat tatataccag
      901 ttgaaaataa tggtaaatta cttacttttt tgtgggtatc tatttatttt aaaacacctt
      961 tttccttaag aatatcttcc ataccattat ccaacataaa gctaattcct atatcttgca
     1021 ttatagccaa agcatccaat atttgtttcc ctcgaatagg tgtaagtgag tattcgactt
     1081 taagtgggta accttcatat gtctttttat ctacaagacc aaattcaatt aattctttaa
     1141 gttgttcaag taacatcttt tgattaatac cattgatttc cttttcaagt tttgataagg
     1201 aagttggtcc tatgcgtaat ctccataata taatagattt ccatttgcct tttatcatat
     1261 catgtgttag ttctaatggg caagtatact catcacgaag tttcaaataa gttcacctcc
     1321 attttacttt gccaagatac attttgaagc aagcttatat acaaactcaa cttttttatt
     1381 tgatatatcc catgaatcta attctttttt tactaaatct ggatattttt tacttatatc
     1441 tctaagagca ttacctacag actttctcaa gtattcgcta tcatcttctt ttaaactaga
     1501 aagtagtgat atagcaacgt caggattaga tttaaaatag tctctactag tccaaattcg
     1561 aagaccttct gtcacagccc tttttatgtt tggactatca gaattaagcc attcttttat
     1621 aacaggaagt gccttttcat atcctacttc actgcaataa taatcaaatg atttagctag
     1681 tatttcttgt actctccagt tttcatcttt actcacatta tcttttaaaa ataacaaagc
     1741 ttcagaaata gttactgata taaaaccaag tataaacaca gccaattctc ttacttgata
     1801 atattctgac ctatataagt agattgatag ataataacac ttttttgagt cattattttt
     1861 tacaattttt ttagcaatgt tttcaatttc tttgaatcca ttttctatag taataatttt
     1921 tgcaattact tcttccaatt ttatctcctc caataaatag attagtttaa attttatgta
     1981 tttatttgta aaaaagtttg tttaatttag acaaaataaa gacttgtcaa aaaacgtttg
     2041 caagtcttta gtactagcat aaataaaaaa taataaaaaa tcaacctcat ttaacatata
     2101 aatttacttt tattataagt tttatattat aaagttgtat ttaaaaaatt aattgagtta
     2161 tataaatttt acatgatttg agtatactaa tagaataaat tattatatag taatacttat
     2221 atgagatgaa tattttacca atcctatttg atggtgtata attaggtgat aaagagtaat
     2281 ttaagcaatt atgataaaga ataacttaag taattataat gatatttaca aataatttat
     2341 aaaacatcat aatttgtttg aagttagtat gacaaagctt acattaaatc aaaaatataa
     2401 ataagtaatt ttaacttgta ataataataa ggaaatatag aaaattatgt gataagtaaa
     2461 aaatgttttg tctgaagaaa tataaaagac aatataaata ataatataat gaaaagtaaa
     2521 acaggaggga aaaatgatac caggacttaa agaaagtttg ctaggattaa taaatgaaag
     2581 tgcatataat cctctaaaaa aagaagaatt agcagaaata tttgatatac attcatcaga
     2641 aatgccaatg ttttataatt ttttaaatga attagaagaa gatggttata tctgctttac
     2701 taaaaaagga aaaatagtat ctcccaatca aatgggatac tttgttggaa aatttgtatc
     2761 acacaaaaag ggttttggat ttgtagaatc tgatgttgaa tatacacagg atttatttat
     2821 ctcaagtgac aatataaatg gtgctatgca taatgataga gttatggcag aaatagtagt
     2881 acctgcaact gaagaaaaga gagcagaagg aagaatagta aaagtaataa agagagaaat
     2941 aactagaata gtaggtactt tccaatcaag taaaactttt ggatttgtaa caccagacaa
     3001 caagaaattt actaaagata tatatatacc taaaaaacat tttagtggag cagtagataa
     3061 tgataaggta gtatgtgaaa ttacagtatg gccacaagag gatagaaaac cagaaggcaa
     3121 aattatagag atactaggtc aaaaaggtga aagaggcgta gaaatagatt ctataataag
     3181 agaacatggt cttccagaag aatttccaaa gaaagtattg caagaagcag aagctgtagc
     3241 tgttgagatt cctcaagaag agataaaaag aagaagagat ttaagagatt taaacatatt
     3301 tactatagat ggagatgacg caaaagactt agatgatgcc atatcaatag aagtattacc
     3361 taatggaaac ttcaaactag gagttcacat agctgatgtt acacattatg taagagagaa
     3421 aaataaactt gacaaggaag cgttaaaaag agctacatca gtttatttag tagataaagt
     3481 aattccaatg ttgccaaaaa ctctttcaaa tggagtatgt agcttaaatc catttgaaga
     3541 taagttaact ctttctatat ttatggaaat agaccataaa ggaaatgtgg ttaaacatga
     3601 aatatgtgaa tctgtaataa attcaaaagc tagaatgact tatacagaag tatctgatat
     3661 attagaaaag gatgatgaaa aacttaaaaa gacttttgaa catgttgttg aagattttaa
     3721 aaatgctgaa attttagcta ggattcttat gtcaagaagg gaaaaaagag gagctataga
     3781 cttcaatttc ccagaggcaa agataattct aaatggaaaa ggcgaagttg tagatataaa
     3841 gccatatgaa agaagaatat ctaataagat aatagaagaa tttatgctta taagtaatga
     3901 gacaattgcc gaacattttt actggatggg aataccattt gtgtatagaa tacatgagac
     3961 accatctttg gaaaaaatgg aagaattgag taagtttata tctacatttg gatatataat
     4021 aaaaggtgat aaagaggaag tacatccaaa agcattacaa ggtataatag agaaaataaa
     4081 gggcaaaaaa gaagaaggag ctatcagtac tataatgctt cgttctttaa aacaagctaa
     4141 gtactcacca gaatgtagtg gacattttgg attagcagct aaattctact gtcactttac
     4201 ttcaccaata agaagatatc ctgaccttca aattcataga ataataaaag aatctttaaa
     4261 taataaaata agtggaaaaa gacaagaaca gcttactact atagtggatt atgcatctgt
     4321 tcaatcatcc gagaaagaaa gaaaggcaga gttagctgaa agagatgtac atgatttcta
     4381 taaggctctt tatatgaagg ataaagttgg tcaagaattt gagggtgttg tatctagcgt
     4441 aacttcattt ggaatatttg ttgagctaga taatactata gaaggattga taagacttgc
     4501 aaatatgaat gatgattact atatttatga tgagagttct tatagtgttt taggagaaag
     4561 aactaagaag tcatataaga taggagacct tgttaagata aaggttgaaa gtgttaatgt
     4621 agattttaaa gaaattgact ttgagatagt tgaaaaaata gaggagtaga taaaacagct
     4681 aaaataagag ataacaagtt gtagtattta tgatatgtat aaatatatag tgcacaatac
     4741 tctataaaat aaatgataaa aataggtaat tgagaaatat ctaatggaaa tagttaactg
     4801 aaagataagt aattaagaga tatttaatgt aaacagataa tttaaaaata cctaattaag
     4861 aatagatatt aaaaaatata atttcaatat aaaaataagt gtatcattta aaatttaaga
     4921 tacacttatt ttttatttaa gataactttt cttttttaga atttataaca ataggttaat
     4981 atatttataa ttaatgtaaa aattattcat atctattaaa tcaaattctt acacatataa
     5041 ttattggtat gcttattaac actccagaaa ctcttatagt ttaaaattta aatttattgt
     5101 tatttattat ttaatttgag aacatgattt attttttatt taaagctaat aagtagagca
     5161 tgattctaca gtataatttc ttaaattttt tttaaaagta atagttctta tttatagtca
     5221 atattgccta tagaacttct gattcattta atttttagga aaaaataata atacttacgc
     5281 tataaacaca gaattttagt tgataatata ggtatttaaa tttaagatga aataatactt
     5341 ttctcaatat attttattgt aactaagttt aattataagt tacaataaaa aaaacgctac
     5401 ttaggaggaa tgtaattatg gggatgatag gatgttatac taaaataagt gaagagaatg
     5461 tttttaaatt acagcaagca gaagaaaact tacaagattt tgtttttgaa gatgccaacg
     5521 aaaatagtac tatcaatatt gataaagcat ggcatgccat tcactttact ttgacaggtt
     5581 gtccttttgg tggagatgat gataatatat ttagcaaatt agtactaagt ggaaacatac
     5641 ttatggaaat tgatagagaa tttcctgtca tgttgattac agcaaatgat gtaaaagaac
     5701 tatcaaaagc aatgaacagt ttggaagaac aagcatttag aaaaagattt aatattaatg
     5761 agatgttaga aaataatatt tatcctgtta tgaatgatga gagtgaagat gatttttttg
     5821 aatatgtatg ggcaaatcta attgagctta aaaagtttat acaagaagca tctgatgatg
     5881 gactagctgt aatatttttt ataatgtgat aattactaaa aattgtgaat attagtgtca
     5941 tcacatatct tagatatgaa gccttttgat tgtatagaag aaaatacata ttatattagc
     6001 cttttaaaat atataagtta aatttaaatc tgtaggtaaa tttgtcttat gtctttataa
     6061 atatttatat tagcatatat aaattagttt taaatttttg caatatatag ttgcagatat
     6121 ttttatttat cttaaaaggc taaataccct atcttattat atccagtaat tcttttggat
     6181 acttatcaca tttttcatta tatataaaaa tagactcaca a
//
LOCUS       DAEPUT010000144         6181 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.148, whole genome shotgun sequence.
ACCESSION   DAEPUT010000144 DAEPUT010000000
VERSION     DAEPUT010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6181
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.148"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..599)
                     /locus_tag="KRL22_003697"
     CDS             complement(<1..599)
                     /locus_tag="KRL22_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBH1274120.1"
                     /translation="MKPELKKLLILNAPYLLFVYLFDKVGQAVRLSPGADLSGKVLSL
                     ADGFSAAFANPLPSFFPADLLIGIVGAVLIRLMVYFKGKNAKKYRKGIEYGSARWGNA
                     EDIKPYTDPVFQNNVLLTQTERLTMNSRPKQPKYARNKNILVIGGSGSGKTRFFVKPN
                     LMQMHSSYVVTDPKGTVLVECGKLLQRGGYRIKVLNTIN"
     gene            complement(596..1072)
                     /locus_tag="KRL22_003698"
     CDS             complement(596..1072)
                     /locus_tag="KRL22_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBH1274121.1"
                     /translation="MQDEVNEKVVSLAIKTSKLTAEVLQKAMKALLAKGKGQLTKAPH
                     GKITMRQLMKPGEKVSNIEITDQNIKAFDPIARKNGLDYNVKKIENGKPPTYLVSFRG
                     KDIDVMTEAFREFTAKKLGRNKKPSIRKLLSTLKDKAAALNAQRDKVKKKDREVSL"
     gene            complement(1155..1373)
                     /locus_tag="KRL22_003699"
     CDS             complement(1155..1373)
                     /locus_tag="KRL22_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBH1274122.1"
                     /translation="MTQKTGALIFDETADRYDIRFDLNDYYGGLHCGDCLEVFVRGKW
                     KPTRMEYGDNWYLVGVRASDLNGLRVRI"
     gene            complement(1394..2368)
                     /locus_tag="KRL22_003700"
     CDS             complement(1394..2368)
                     /locus_tag="KRL22_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274123.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKELSLKAKGLLSQMLSLPEDWD
                     YTLAGLSLINRESIDAIRTAVWELEKAGYITRRQGRDEKGKMTAIEYTIYEQPQPPTL
                     DCPVLENPTADKPILENPTPDNPTSENPTQLNKELLKTNLPKKEKLNTDISNTHSIPF
                     HSLNPSPLEDAAQPPERKRKETTDAYRVYEEIIKDNIEYEHFIKHTDFEKERLDEIVS
                     LILETVCTKRKTIRIAGDDYPAELVKAKFMKLNSSHIEFVFACMSENTTKIRNIKQYL
                     KAVLFNAPNTIDSYYTALVNHDMYGGRTIQSARSKGIPDYTYNEGESL"
     gene            complement(2939..3160)
                     /locus_tag="KRL22_003701"
     CDS             complement(2939..3160)
                     /locus_tag="KRL22_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HBH1274124.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            3740..3997
                     /locus_tag="KRL22_003702"
     CDS             3740..3997
                     /locus_tag="KRL22_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1274125.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENSV"
     gene            4466..5704
                     /locus_tag="KRL22_003703"
     CDS             4466..5704
                     /locus_tag="KRL22_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH1274126.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYLSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDKNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISVLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         2049 a          953 c         1149 g         2030 t
ORIGIN      
        1 aaattgattg tattcagcac ctttatccga tacccgccgc gctgtaagag cttcccgcac
       61 tcgactaaaa ccgtcccttt cgggtcggtt acaacgtagc tgctgtgcat ttgcattaag
      121 ttgggcttca caaaaaatct tgtcttgccg ctgccgcttc ccccgataac aaggatattt
      181 ttattccttg catacttcgg ctgcttcggg cggctgttca tggtaagccg ttccgtctgt
      241 gtcagcagca cattattttg aaataccggg tcggtgtagg gttttatatc ttcggcgttg
      301 ccccaacggg cagaaccgta ttctatgcct tttcgatatt tcttcgcgtt cttgcctttg
      361 aagtacacca taagccggat aaggacagcc cccacaatac cgataagcaa atcggcagga
      421 aaaaaactcg gaagcgggtt tgcaaaggca gcggaaaagc cgtctgcaag ggaaagcacc
      481 ttgccggaaa ggtcagcccc cggagagagc cgcaccgcct gtccgacttt atcaaagaga
      541 tagacaaaga gcagataggg ggcatttagg ataagcagct ttttaagttc cggcttcata
      601 gagatacctc cctgtccttt ttcttcactt tgtccctctg tgcgttcaga gctgccgcct
      661 tgtctttcag agtggaaagc agcttgcgga tagagggctt tttattcctg cctaatttct
      721 ttgcggtaaa ttcccggaac gcttcggtca taacgtcaat atccttgccc ctaaaagaca
      781 caaggtaggt cggcggcttg ccgttctcaa tcttcttgac gttgtaatca agcccgtttt
      841 tccttgcgat agggtcaaag gctttgatat tctggtcggt aatctcaatg ttggaaacct
      901 tttctcccgg cttcataagc tgccgcatag tgatttttcc atgcggggct ttggttagct
      961 gccctttgcc tttggcaagc agggctttca tagccttttg cagcacttcg gcggtcagct
     1021 tagatgtttt gattgctaaa gacacaactt tttcgttgac ttcatcttgc atgaaatccc
     1081 tcctttcgtg gttttgttag ggtggtgtgc cgcttcgggg cataaaaata aggcgtacat
     1141 ttttcatgcc acctttagat acgcacccgc agcccgttca aatccgaagc cctcacaccc
     1201 acaagatacc agttgtcccc gtactccatg cgggtcggct tccatttgcc gcgtacaaac
     1261 acttcaaggc aatccccaca atgcaatcct ccgtagtagt cgttaaggtc aaagcgaatg
     1321 tcgtaacggt ctgctgtttc atcaaaaatc aaagctcctg ttttctgtgt cataataaaa
     1381 tcctcctttg gttttacagg ctttcgccct cattgtaggt gtaatcgggt atgcccttgc
     1441 ttcttgccga ctggatagta cgcccgccgt acatatcgtg attgactagg gcggtgtaat
     1501 agctatcaat ggtgtttggg gcattgaaca gtaccgcttt cagatattgc ttgatgttgc
     1561 ggattttggt ggtgttctca ctcatacagg caaaaacaaa ctcaatatga ctgctgttca
     1621 gcttcataaa ctttgctttc acaagctctg ccggataatc gtccccggcg atacggatag
     1681 tctttcgttt ggtgcagacc gtttcaagga taagggacac aatctcgtct aagcgttctt
     1741 tctcaaaatc agtgtgcttg atgaaatgct catactcgat attgtccttg ataatttcct
     1801 catacactcg gtatgcgtct gtcgtttcct ttcgcttccg ttccggcggc tgtgccgcgt
     1861 cctctaaagg agagggattt agggaatgga aaggaatgga atgggtattt gatatatctg
     1921 tatttaattt ttcttttttt ggtaagttag tctttaatag ttctttattt aattgcgttg
     1981 gattttccga tgtcgggtta tccggtgtcg gattttccaa tatcggctta tccgctgttg
     2041 gattttccaa taccggacaa tccaatgtcg ggggctgtgg ctgctcgtaa atggtgtact
     2101 cgatagcggt cattttgcct ttctcgtcgc gtccctgccg ccttgtgata tatccggctt
     2161 tttcaagctc ccatacagcg gtgcggatag cgtcgatact ttcccggttg ataagggaca
     2221 gccctgcaag ggtatagtcc caatcttcgg gaagtgaaag catttgcgac aacaagccct
     2281 ttgcttttaa ggaaagctcc ttgtttcgta aatggtggtt gctcataacc gtataacctt
     2341 tattcttttc cacgcggaaa actgccatag cttcatcact cctttggttg gatttgttac
     2401 gcagtagaaa cgcggttttg agggaaaagg tatcaaccct tgcctttctc attttcacgt
     2461 cctaagagcc gcataaatca aggctttttt gccccttact gcgtaacatg agggcataaa
     2521 aatagcggcg ttcctgttct cctgtgtagg agtgagaaac gccgccttat aggtggtgct
     2581 tattttattt tttcttttcg acgtgccgcg taaggtggtg tagcggtcta tccggcagct
     2641 ccgcaggtgc ttttgcatat caaggcgcaa tccgttaaaa gtagtaaatg agtagtaaaa
     2701 tcaatctgca aacctgcgaa tatgcccgta aatcaagcat ttttcaagac aatcaactaa
     2761 tttcaattaa atacgtttaa tatattaatt tttcaaagca ttaatatatt aaagttataa
     2821 tcaaaattga agttataatc tgccaaatct atagcgtatt aagtgcgtta tataacttaa
     2881 tcttttatat aaagagttaa tttttttaat ttgtaaagca gagtacgttt aaaaggtact
     2941 atttagataa tgatgtacta tctaatttta aaatatctac aatagggttc tcttgaagac
     3001 ttgctattgc ttctgcaaca gcataaacat cttcatttaa tgcctctgct tttacatttg
     3061 caaatgattt acttttaaca actgccttac ccttatcatc aaaaccagca tccaatttta
     3121 gttttatact agataaattt tttgttgaaa caacttccat aaaattacct cctaaaaatt
     3181 taatttcaaa gatttgtcga ctttctttgt tagctataat actatcatct aagataatat
     3241 cggagttaaa cagtaatttc taaagatttt ttgtgtaaat ttttatagga aaaattttac
     3301 ttttttgctg atgaaaaagt ttacaagtta tttgtgaaga tatgttctta gtgttttgaa
     3361 atagtatttg tatatattca tgcttagttg agatagtttt gtatggattt tcatatgtgt
     3421 agagttaaat gttaggtact aaagtttatg ttaaattaaa tgttaaagct tatgttaaaa
     3481 attttattaa atttaatctg taaataaaaa agttaaaagt ccaatattaa cattttactt
     3541 ttaaaccatt aaaatcttta ttaaagctaa caaagttata agttatgaga aattttatta
     3601 aagttaatac aaaaattaat tttaaagcta agaaattatt tattagattc aataaaacta
     3661 ataaatatag tttagtcaat aatgtattaa ataaaaactt tgttaagtct ataaaaatat
     3721 cttaaaggag gtgtaactta tgaagataaa agtggaggat ataccagttc aatttcatgc
     3781 aatggtagaa ataattggaa ttgataagtt catagaggtt gccaagttgt atggaggaac
     3841 aaatacttat atacctacgt ataaggggct ttttagatat gctagaaata gggatatagt
     3901 aaaacaattt aatggagtca accacaatga attggctatt agatataata tgtgtgtaag
     3961 caatattaag cgaatactca atgaaaatag tgtttaaata taataaaata atgtttaaac
     4021 ataatgaaaa tagccttgtt aaatgtaaga gcaaagacaa agaagatgtt ttataaagtt
     4081 tttttagaca aattaactaa atttactact tattaattta aatacattgt atattctata
     4141 aaaaaatttg ttaaatactg gagatatatt gagaatacaa agaaaatggt cgaaaatatt
     4201 tgttggctaa aaaatagata aaatgataca attgcttgta taaaggggaa aaataaacaa
     4261 ataaactata taaataaaga aatagcaatt aatatgacat aatatattta taaaattaag
     4321 aatataaata gatattttaa ggtattagtt gttaaattag gaaatattaa aaaaaatata
     4381 tatttatatt taaactattt tgttatttat ataaaaatac ttatctagtt actagcaatt
     4441 attagtagaa atgggggaaa tagagatgaa taagggattt tacaaattaa attcagtggt
     4501 attgaacttt gatattaaga atgatgttaa caagataaga tttaatcatt atataatgag
     4561 aaaagaaaac atacaaagac ttcaaggaac tctgccaaac ggacaatttt atatgacagt
     4621 gagaagagct gctacagatt tacaactttc tatttctact ataagtaggc ttgtaaaaga
     4681 gtttttggat ttagggataa taagattagt gtctaagggt gtaaaaggta atcgttctgt
     4741 atatagttac gtaagtatag agtttaatgg aagtttattt gatgatagta aatatatgga
     4801 acttgactgt gtatgtaatg atgaatttat tgataatagt ggcatagagt ttgattgtga
     4861 tagcaaagat aattctttta atggagatat aaatgtagaa actgtgcatt gcattaatga
     4921 gtatttgtct gatgatgatg tagagcataa ttataacaat ttccataata aagatactat
     4981 aaaggataaa gccatttcta atattagcac tatcaaaaaa tatattgatg aatcttttga
     5041 taaaaataaa tcagaaaatt ctaacttaca acaggagtca ataaatttca actttaatga
     5101 tacatgcaat gaaatagata aaagaacgaa taatagtata gaaaataatc aaaataaaag
     5161 gcctatgaga ttgagtgaca tcagtgtttt aagtgataaa ggtatgacaa ataaaaagaa
     5221 ttactttaat cataatcatg gtatacaaaa agggactaaa tctgtaacaa agaaaaaaga
     5281 atccttaaat aaatttaata aaaaaaatat acagcaaagc attataaata tgctaaataa
     5341 aaaatcaggt aagaatttta aaatcgattc tccaataagc ataaaactta tcaatgaaag
     5401 gctaaaggaa ggctatgtct tagaagattt ctacaaagtt attgaggtaa aagtggctaa
     5461 gtggaaaaat accataatgg agatgtatat aagaccagaa accttgttta gctataagtt
     5521 tgaatcctat gtaaatgaaa acatatctat gaaaagtcaa agtaatgttc acccatgtaa
     5581 agaaggcaat agtaatgata gcagtaatta tatacattct gattatacaa catatgatgg
     5641 cagtgtgcgt gagagaaaaa aatatgagaa tgtaagatac tggaatccta tatgtgagat
     5701 ttaattagtt taagaatgta tttatgataa ataagatatt aatagagaat agtgagctat
     5761 agcaaatgat atatcaatag ttggtagtaa gttatattaa gtaagatatt actatcaggt
     5821 agtgaattat attgaacgat atatcaataa ttggtagtaa attatattaa gtaagatatt
     5881 actatcaggt agtgaattat attgaacgat atattaataa ttggcagtaa attatattaa
     5941 ataagatatt actatagagt aatgaattat attgaacgat atatcaataa ttagtagtaa
     6001 gttatattaa gtaagatatt actatcaggt agtgaagtat attgaacaat atatcaataa
     6061 ttgatagtaa attatattaa gtaagatatt actatcaggt agtgaattat agtgaacgat
     6121 atattaataa ttggcagtaa attatattaa ataagatatt aatattggat agtgaattat
     6181 a
//
LOCUS       DAEPUT010000145         6071 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.149, whole genome shotgun sequence.
ACCESSION   DAEPUT010000145 DAEPUT010000000
VERSION     DAEPUT010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6071
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.149"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(181..2775)
                     /gene="clpB"
                     /locus_tag="KRL22_003704"
     CDS             complement(181..2775)
                     /gene="clpB"
                     /locus_tag="KRL22_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBH1274127.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(2812..3408)
                     /locus_tag="KRL22_003705"
     CDS             complement(2812..3408)
                     /locus_tag="KRL22_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274128.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(3425..3829)
                     /locus_tag="KRL22_003706"
     CDS             complement(3425..3829)
                     /locus_tag="KRL22_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HBH1274129.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            4196..4570
                     /locus_tag="KRL22_003707"
     CDS             4196..4570
                     /locus_tag="KRL22_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1274130.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            4567..5430
                     /locus_tag="KRL22_003708"
     CDS             4567..5430
                     /locus_tag="KRL22_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1274131.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREYYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            5430..6068
                     /locus_tag="KRL22_003709"
     CDS             5430..6068
                     /locus_tag="KRL22_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH1274132.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
BASE COUNT         2012 a          930 c          694 g         2435 t
ORIGIN      
        1 tcaaattatg attatattat aagaaattta ctaaaatact tcctttgagt taaatttaat
       61 ttggacatat tgacttaaaa atgttttatt aatttgataa aatatttctt ttcctatagt
      121 ttataaataa aaatcagctg agcaaaatat ttagtatatt atgctcaact gattctttta
      181 ttatttaact aaaacttcaa tattttcatc ttttccatct ataactatag tacatccatt
      241 atacacatct ccagcaataa gtttctttgc aattatagtt tctaatgtat ttcctatata
      301 tctcttaaga ggtcttgctc catatacagg gtcatatcct tctctcacca taacatcttt
      361 tgctgaattt gtaacttcaa tagtaatatc tttttctttt aatctatttt ttaaatcttt
      421 cataaatata tctataattt tcttgatatt ttcttggtct aaaggcttaa acattataat
      481 atcatctact ctgtttaaaa actcaggttt aaatctatgc ttcatttcat tcattactaa
      541 attgttagta gtctctgtta tatttcctcc tgcttctaat agataattac ttcctatatt
      601 agaagtcatt attataagag tatttttaaa gtctactgtc ttacctttat tatcagtaag
      661 tctaccatca tctaatatct gtaagaacat gttaaataca tcctcatgtg ctttttctat
      721 ctcatcaaat agtattacag aataaggagc acgtctaact gcttctgtaa gttgaccacc
      781 ctcttcatat cccacgtacc ctggaggagg tccaactagt cttgatacag catgtttttc
      841 catgtattca gacatatcta ttcttattat attatcttca ctatcgaata aatttctagc
      901 aagagttttt gcaagttcag ttttaccaac acctgtaggg cctaagaaaa taaatgaacc
      961 aattggtttt ctttcatctt ttaatcctgc tcttgcacgt attactgcat ttgaaactgc
     1021 tgtaactgct tcatcttgtc caataactct tttatgaagt tcatcttcta gtttaagtaa
     1081 tttttctctt tctccttcaa ctagtttagt tactggtata cctgtccact ttgatacaat
     1141 gctagatatt tcttcttcag taacttcttc ttttaaaaga gaattttcag aaccatcatt
     1201 catattttct tcgtactgct ttatttgttc ttctaactta ggtatttcac catatttaac
     1261 ctctgctgct ttgttgaaat catattctct ttcatacttt tcagctttac ctttagcttc
     1321 gtctaattga gcctttaagt ttttaatatc taatatttga ctcttttctt tttcatattt
     1381 tgctgtcatt tcatcatttt tagattttaa ctctgctatt tctttttgaa tatcatccaa
     1441 tcttgattta cttttatcat cattttcttt aagtaatgct tctctttcag tttctaatgt
     1501 aaataacttt cttctaacaa catctaattc tgttggcaat gaatctattt cactacgaat
     1561 catagctcca gcttcatcaa ttaaatcaat tgctttatct ggtaaaaatc tatcttgtat
     1621 atatctatga gaaagttttg ctgctgctac aatagcatta tcatgtattc ttactccatg
     1681 atgtatctca aatctttctt ttaaacctct aagtatagat attgtatctt caacagtagg
     1741 ttcttctgca attacaggct gaaaacgtct ttcaagagcc ttatcttttt ctatatactt
     1801 tctatattca tcaaaagtag ttgcaccaat acagttcaat tcacctcttg caagcatagg
     1861 tttaataaga ttacctgcat ccattgaacc ttctgtttta ccagctccaa caatagtatg
     1921 aatctcatct ataaacagta taatttttcc atcagaactt tgaacttctt ttaaaactgc
     1981 ctttaatctt tcttcaaatt cacctctata ttttgcacca gcaattaaag ctcccatatc
     2041 aagtgagaat acaatcttat cttttaaacc ttctgggaca tctcctctta ctattctctc
     2101 tgctaaccct tctacaattg cagttttacc tacacctggc tcaccaatca atacaggatt
     2161 attttttgtt cttcttgata aaattcttat aatccttctt atttcttcat ctctcccaat
     2221 tacagggtct aatttatttt tcttggctaa atctactaaa tttgttccat atctagcaag
     2281 tgcatcatat gtgccttctg ggtcttgtgt ttctactctt tgactacctc tcacttgtga
     2341 taaaatattt aaaaagtcat tcttatttat attatattgt tttaatattt taccaacagc
     2401 tgattttgat tctgtttcca tcattgcaag cataacatgc tctacactta tatatgaatc
     2461 tttaaattct ttagaaatac tctctgcctt tataagcacc tcatttattt ttctagtagc
     2521 tgatactcct tgtgagtcag caccttctcc atatactttt ggaagcttat caatttcaaa
     2581 gtttacagta tttctcaaag aatcaattga tatattcatt ttttcgatta tatttggtat
     2641 caatccatcc tcttgattaa taagtgctga gaaaagatga attacatcta cttgttggtt
     2701 atgatttttt actgcttcgt tataagcctc atttaaactt ttttgaactc ttaaagtcat
     2761 tttttctacg tccatataaa tccctccatt ttaatattat atccaaataa attaaattct
     2821 ctcatttata attattgatt ttctaagctc taaaagacta tcaagtaaat tctcgttttt
     2881 ttgtatatcg aaactcaatg ttaaattaaa tgttccatct gaattaaaaa aatcgaatac
     2941 ttcttttgat tttgctatta aatacaagtc ttcatctata agtctttttt cacctattaa
     3001 taaatactga catttatcta taaaactctt tttaaaatca atagtgtata gattttctaa
     3061 aatattatat tgataaatag caatattatt aaacactttt aatatgtttg aatttacaaa
     3121 attgtaaatt tgattattgt tatacagtga tatttgttcg tatatatatt ccctaaataa
     3181 aggatgaatg ttttgcttaa gttttaaagt aacttcagct ggtatttcaa aataaagctt
     3241 ccagtactta gagttatttt tttctaaaat aaaagctact ttgttcaaac tggtagaact
     3301 aatctccttt agtgtacaat taaaattata gtgtctcaaa ctagtttttt cattctcaaa
     3361 tacatagtca aaccactgta gaacatttct atcaagtttt aaactcatat aaaaaccttc
     3421 ttccttattt actaacctta ttaggtcttt ttatctgatt atattctgct aataaacttt
     3481 ctttatcagc tctactacct ttatatgcta tatgtggatt tatcatatac tcaccatttt
     3541 tcactctttg taaaaaatcc atttttttca gctccgtaaa caatgaagat aaagaagttt
     3601 ttggatattc aaattcacaa gataattcat ataatgtttt tctaatctta ttatttttat
     3661 ccatagagtt tattaatttt aatggaatta aatccctctt agtatacatt ccttctacta
     3721 ctttaatata attcttaaaa caaacattca tatacttact tttattcata actaaacttt
     3781 tgctctctgt atattcctga tttaaatcct tttttaatgt cttatccaaa ttaaatatct
     3841 cttctcactc tccttatctc taattgataa tataaatata ttacaaaaaa atatgtatgt
     3901 caaaactgaa aatgcaaaaa gttcacctta taagcaaact tttatttagc tataagctaa
     3961 actttattat ttttttaatt tagtatttcc aatttattgg caggattttt gaacaatatt
     4021 tataaatttt ttaaaaaaat ttaaatctat ttaatatggc agactttcat aaaatacatt
     4081 acatttatta aatgtataat attggcaatt agttttttct aaaatcagtt gacatattat
     4141 atatatattt atataatgtg tatatactat atatacaatt taaggaggtg tcttattgaa
     4201 tatagttatt agtaattcga gtgggaagcc aatatatgaa cagattacta cacaaattaa
     4261 aagtatgatt ataagtggag agttaccaga aggctcagct cttccaagta tgagactatt
     4321 ggcaaaagaa cttagaataa gtgtaattac tacaaaacga gcatatagcg atttagaacg
     4381 agacggattt attgagacag ttactggtaa aggcagtttt gtatctagta aaaacatgga
     4441 ttttgtcaaa gaagaacaat ttcgtttaat tgaagaatac ctacaaaaag cagttgatac
     4501 agcaaaaagt agtgatatta catatgacga attaaaagat attttatttt tattatataa
     4561 aggagaatga taagtatgga tgcaataact ataaaaaatt taaataaaac ttataaagat
     4621 tttagcctac aagatatatc tttttcagta ccaaaaggga gtgtaatggg atttgtaggt
     4681 gaaaatggtg caggaaaaac aactacatta aaagcaattt taaatttaat atcttatgat
     4741 agtggaaata tagaaatctt tggtcttgat agtaaaaaaa atgaaaaaga aattaaagag
     4801 caaattgggg ttgtatttga gggaagcaac tttcatgaaa atttaaacac tgaccatgtt
     4861 tcaaaaatca tgagtaaaat ctataaaaat tggaatgaca ccttatttaa agactactta
     4921 aaaaaattga gagtaccaga caataaatta attaaggagt tttcaaaggg gaataagatg
     4981 aaacttagta ttgctgtagc cttatctcat aaaccaaaat tattaatact agatgaggca
     5041 actagttcac ttgaccctat cgttcgtgaa gaaatactag atatattttt agattttata
     5101 caagatgaag aacactctat tatcttatct tcacatatta caagtgattt agataagata
     5161 gcagactata ttacatttat acataaagga aaaattgtat ttagtgaaaa taaggatgaa
     5221 ttaattgata ctatgggagt tttaaaatgt aaacctagtg attttgataa cctttcaaga
     5281 gagtattatt catattatcg taaaagccaa tttggatatg aagtacttct taaagataaa
     5341 catagattta tctcaagaca tccaaactgt attgttgata atacgtctat agaagaaatt
     5401 atgttatttt atgtgagagg tgataaataa tgaaaggtct aattttaaaa gatttactta
     5461 atttgaaagg aaatataaag tttatacttt tattcatcat tatgtttggc tttatgtctt
     5521 ctttaggaga tggaaatgtt aataacttta taggtgttat tatagtttta tgtactacaa
     5581 tgattgtttc aacattttca tatgatgatt tgaataaatg ggatagttat gtacttacaa
     5641 tgcctattaa tcgcaatgat attgtattaa gtaaatattt aactatgtta atatttagct
     5701 ttataggtgt tcttgtttca cttattgtta gtgtaactat tggttatttt aaaaatacac
     5761 ttatattaaa tgaaacacta cttattaatg cactaatctt atcaatttca gtatgttttg
     5821 gtagccttat tctaccactt atttataaat ttggtacaga aagagctcgt ttattaatga
     5881 ttttatgctt tttagttcca acactagctt tattagtttt taaaagtatt ttagaaaata
     5941 ttagttcacc tatttctata gaaattatac ttaatacact agtatattct cttccatttg
     6001 ttgctatttt actatttgtg atttcatatt ttatatcatc aaaaatctat agtaaaaaag
     6061 aagtataaaa t
//
LOCUS       DAEPUT010000146         5967 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.150, whole genome shotgun sequence.
ACCESSION   DAEPUT010000146 DAEPUT010000000
VERSION     DAEPUT010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5967
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.150"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            37..1344
                     /locus_tag="KRL22_003710"
     CDS             37..1344
                     /locus_tag="KRL22_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274133.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEAFDCNLASKNI
                     RLLLDTCKVPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    1430..1692
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1818..2621
                     /locus_tag="KRL22_003711"
     CDS             1818..2621
                     /locus_tag="KRL22_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1274134.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            2659..3270
                     /locus_tag="KRL22_003712"
     CDS             2659..3270
                     /locus_tag="KRL22_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH1274135.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3302..3973
                     /locus_tag="KRL22_003713"
     CDS             3302..3973
                     /locus_tag="KRL22_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH1274136.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            4272..4634
                     /locus_tag="KRL22_003714"
     CDS             4272..4634
                     /locus_tag="KRL22_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBH1274137.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            5070..5771
                     /locus_tag="KRL22_003715"
     CDS             5070..5771
                     /locus_tag="KRL22_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HBH1274138.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDKEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSIKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
BASE COUNT         2391 a          545 c         1040 g         1991 t
ORIGIN      
        1 attgagtttt acataaaagc aaaggtggga ataaaaatga aagaaattgc tgatgctata
       61 acatcagagt atttaagcta tggtatcaat gaagatatta gtatctatga aggtagattt
      121 tgcatatatt tagataaaaa atatagatgt aatgggaaaa tttattataa aatgacacct
      181 ccaatatcta taagttttaa agcagacata ggttgtgttg aagagataga caatgaagat
      241 gacaatttag ctttagatta tgataatgct attcttgaag ttcatggata taaaattatt
      301 tctataacaa taaatacttt aagtgaattt agtgtagaag gttatatcaa tgatgactgc
      361 ataaaatcta agaactccta tgttgaatat gtagatttta atataataaa cttagataaa
      421 atacctggaa aactcattaa atacaatgat aaggtatacg caggtagaat tgaatttgat
      481 ataaatgatt atgttgtaac tatagacaag cgatatgatt atagaaaaga attaaaatca
      541 gaattaaagt ctaaatctgg agcaataata actcatatag gtaggattag aagaaaagat
      601 ggtagaattt ttagaacaaa taatacaata aatcttttag ataggatatc aacagctttg
      661 agttttatgt gtggaagata tgtagggttt tgtttggcca aagggtatag aagtggtaat
      721 gaagtttata gaatatggaa tgaaaatcaa atatctcctt ttagatatgt accaacatgg
      781 tcagatacac tttcaaatta tcataatatg gaaaaatata taagccttat gtgtaaaaag
      841 ctagaagatt tttattatgg ttctgctata aagagtgttg ttgattggta catagaatct
      901 cttggaagtg ctaccatgga aaacaatata atatctgtac aaattgcact tgaaactttg
      961 tcatatgtaa ttctagtgga acaaaataag atacttacag atgaagcatt tgactgtaat
     1021 ttggcatcta aaaatataag acttttactt gatacatgta aggtaccata tggtaaacat
     1081 gaattaaata tatttgataa tataataaaa aataaatttg atgatggagt ggatttagtc
     1141 atttatttaa gaaatagcat agttcatcca agtagaaaga ctcatagagc tgtgttagag
     1201 gttgaagata tttggaatat aatttcaata ggaacgagat atattgaact tgttttactc
     1261 tttattttag gttatagagg agaatattca aacagattag tagaaagatg ttatggtgaa
     1321 gtggaagttg taccttggaa ctagattttt atatttattt taaaatatat attgacatat
     1381 attgccttat gctataaaat caatatcata ataataattc agaataacat taaatgctaa
     1441 gaaaagaaat agtaaaagta gttaatctta aacagagagt ttccgattgg tgagaggagc
     1501 aatagatttt actttgaaca catctttgag caggactctg aaagagtaga aatactttat
     1561 taggagattt ccggaatcct tgcacccgtt atagtgctag agtataataa ttttattgta
     1621 cttaaagagg ttagtgtcgt gaggcattaa tgaacagagg tggaaccacg agagttaact
     1681 cccgtcctct agcagaagct agaggcggga gttttttaat ataatttttt aagcgcgcag
     1741 agaattatat tgcaatagat acacttttta aaaaataatc aaaatatttt aaaaattaaa
     1801 agacgaggga gaatattatg aaaaatatat taaaaaaagt aggaatattt acaattatgt
     1861 taggtttatt aggtggagtt gtaggttgtt caaaaccaga taatgaaaaa gataaggatg
     1921 cttcaaagga atctaaaaaa gaagtagttg tagggtttga taatacgttt gtaccaatgg
     1981 gatttttaga tgaaaaggga gatacagtag gatttgacgt agacttagct aaagaaacat
     2041 ttaaaagact tggaatggaa gttaagtttc agcctataga ttggtcaatg aaggaaactg
     2101 aattaaatga ttcaaaaact gtagatgtat tatggaatgg atattctata acagacgaaa
     2161 gaaagaaaat agtatcatat acagaaccat atttacaaaa taagcagata atagttactc
     2221 taagtgactc aaaaataaat tcaaaagctg atttaaaaga taaagaagtt ggaacacaac
     2281 aaggttcaac agcacttgat gcagtggaaa aggataaaga ttttatgaat agcttaaaag
     2341 gtggagcacc agttctttat gatacttatg ataaagcact tagagattta gagataggta
     2401 gaactagtgc agttgttggt gatgaagttt taattagata ctatatggga caaaagggtg
     2461 aagacaaata caaggtatta aaagacgatt ttggattaga agattatgtt gtagcaactt
     2521 ctaaagaaaa tccagaactt tgtgagaaaa taaatgaaac attaaaagaa atgaaaaaag
     2581 atggaacttt tgacaaaatt tatgataagt ggtttaaata gaagataagt tagctgttaa
     2641 gaagggggca ctaaaggcat gttacaaggt ttagagatag ttatagcaat gttttgtata
     2701 acattgatag tatcaattcc attggggatt ggagttgcat ttttaagatt atcaaagaat
     2761 aaattagtaa gtggtattac acaatgttat atattgataa tgagaggtac acctttactt
     2821 ttgcaaatga tagtcatatt ttacggatta cctcttttag gaattgtatt tgacagattt
     2881 acagctggag tagtagcttt cttcttaaat tatgcagcat attttgcaga aatatttaga
     2941 ggtggaatac agtcaatcga tagaggacaa tatgaagctt caaaagtact aggatttgat
     3001 aagtttacta tgtataagag agtaatcttt ccacaagttt ttaaaagaat actagcacct
     3061 atttcaaatg aagtaatcac attagtaaaa gatacatctt tagtatatat attaggatta
     3121 aatgatattt taagaatatc tcaaatagca atgaacaggg aagcaagtct gttaccatta
     3181 tttgaggcag gagcgatata tcttatattt gtagctatac ttactaaggg atttgaatta
     3241 cttgaaaaaa aatattctta ttatagataa agttacaata ttataggagg aggtttttta
     3301 tatgttgaaa atcaaaaact taaataaatc atttaaaaaa aatagagtac ttaaagatat
     3361 ttcttttgag ttagaagaag gtcagattgg agttttactt ggtaagtctg gtgcaggaaa
     3421 gaccacaata ttaaggtgta taaatggtct tgaagaattt gatagtggag agattataat
     3481 agataatgag gtaataaaaa ataagagaga tatggcaaaa atacgaggaa aaataggtat
     3541 ggtttttcaa aatttcaact tatttcctca tatgacagtc cttgaaaata taattgaatc
     3601 cccagttaat gtttttaaag ttcctagaaa agaggctgaa gagagggcta gagaactttt
     3661 aagattagtt gatttagaag ataaattaaa ttcttatcca tttgaattgt caggaggaca
     3721 gcaacagaga gttgctatag ctaggtcatg tgcattgatg ccaaaagtcc tttgttttga
     3781 tgaacctact tctgcacttg atattgatac tattcaaaga gtagtcaata taatgaacag
     3841 acttaaagac aaaggtatga caatattaat aattacacat gatgttgtct tctcaaataa
     3901 tgttgcagat aaaattataa gtataaaaga tggtatagta gaaaatgttc aaataaaaga
     3961 aaaaattgtt tagagtttta taaatataac ctagggtaga attttataat ataaataaag
     4021 ggcaagtaaa atcaaatata ctatgccctt ttgttatctc aaaatttaat cttatatttt
     4081 atgtttaagt tacattataa tttataataa aaataaaagg actatttaaa tatataatgt
     4141 gaataaatgt ttaataattt gaaatatgat aattttttat gttgaaagct tataatgatt
     4201 atgatataaa ttggttatag tatacaattt atgggtataa caataaaaaa ttagaaagga
     4261 atttttataa aatgattaaa ttatatggat atacaaaatg ctctactgtt aaaaaagcta
     4321 aaaattggct taaggaaaat aatttagaat ttgaagatat agatatggtt caaaatcctc
     4381 ctagtaaaga ggagttaaaa tcaatttata agactagtgg atatgatata aagaaatttt
     4441 ttaatacaag tggtatgaaa tatagagaat tgggtcttaa agatattgta aaaactgaat
     4501 ctgatgataa acttttagaa atattggtaa gtgatggtat gcttattaaa agaccattac
     4561 ttttggatgg taaaaatgta ttattgggct ttaaagaaga tgtatggaaa agtactttgc
     4621 taaaagaaga ttagaaagag ataggtgtgt tgattaaaat tattaattaa tacacctata
     4681 aatttatgta ttaaatctaa tttttataaa tattaattag caaattcaaa tcaaaaaaat
     4741 tcatatcaac aaacatatta cttcttatta caaattatat catatgtttt atattaaaat
     4801 attataatat tacaacgaat tgttacaaaa ttacttatta ttaaccatga acatttgttt
     4861 tgtgctatca tatttatata agggaattgt cataaaaaat atcttgttca tacagtttta
     4921 tatagaaaaa agaaatgaat cttttcttta tataagtata ttttgtaaat tgcctctata
     4981 tttatagttt aaataatagt ggtattaaaa atctgacaac aaaaataaaa ctttcaaaaa
     5041 attaaatcta aaaagaatag gagataaata tgagtattga agatttatat gattttgaat
     5101 gtgttccttt gaacaatgag attgatattg atgttttatt tgaaaagatg atagaagatg
     5161 gaaaagaaaa agaatataca ccaattatag tcattgatga aaaagtaggg ctattaagaa
     5221 aaaatataga tatgattact aaagagtatg gttctcttga aaactatagg gagtattgtt
     5281 taacaaaata taatgaaatt gatgtaaatc aattttttga ttttaggaag agtgagattt
     5341 cagaattatt aaaggagcta attgatttag aagatgattt ttatgattat aaacatttta
     5401 gacccattat gaatatagat atatttcatg aatataacaa agtttacata gctaaaattc
     5461 caacaattaa accatatgaa gtatttgcat acatacctat tggcggattt aatgattgtc
     5521 ctagagataa agaacatata gctattgcaa aatattggta tgaaaagcat ggaatctttc
     5581 caatcgcaat tggatgtgat acagttcaat attctataaa aaatttaact aaagatggta
     5641 aaaaatttga tgacttatgt attgaattag tattttattg tgaggatatt attatacaag
     5701 ggtatgaaac cttaaaggct cttaaggatg tattaaaacg ctctacaata gtgctttttt
     5761 ggtgggattg atattctatc acttagacag cattaaattg ttagtcacca agaatccact
     5821 tgctttagtt atggggagtg tgtcaaacta ggtttttata cacagtgtag catagtaata
     5881 tgtttaaatt acaaaggtta aaaaaatact ttaatatttt taatattata attaatagat
     5941 ttaaaggtaa ttataattta taaaata
//
LOCUS       DAEPUT010000147         5861 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.151, whole genome shotgun sequence.
ACCESSION   DAEPUT010000147 DAEPUT010000000
VERSION     DAEPUT010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5861
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.151"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..984
                     /locus_tag="KRL22_003716"
     CDS             <1..984
                     /locus_tag="KRL22_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007037036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBH1274139.1"
                     /translation="TLLEMINASEAREDDPEFQSPVDLMFERLEEKDPEHFAVRQYKK
                     FLLSAGKTRSSILISCGARLAPFDIKELRDLMETDEMELDTIGDRKTALFVIISDTDD
                     TFNFVVSILYTQLFNLLCDKADDEYGGRLPVHVRCLLDEFANIGQIPKFEKLIATIRS
                     REISASIILQSQSQLKAIYKDNADTIVGNCDTTLFLGGKEKTTLKEMSEILGKETIDS
                     FNTSENRGREVSHGLNYQKLGKQLMTEDEIAVMDGGKCILQLRGVRPFFSDKYDITKH
                     PNYKYLSDYDKKNTFDMEKHLRRRPALVKPDEVFDYYEISESDLQEDTDHE"
     gene            977..1144
                     /locus_tag="KRL22_003717"
     CDS             977..1144
                     /locus_tag="KRL22_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274140.1"
                     /translation="MNKRIRKKKDKKITEAINGLVFIAERREQQRQAAIRQFVKRCEA
                     LYEQKRVRREL"
     gene            1164..1331
                     /locus_tag="KRL22_003718"
     CDS             1164..1331
                     /locus_tag="KRL22_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274141.1"
                     /translation="MSRQKTKTDDIRREHYFTKMIENAENALREDLQERGGEQTLYVT
                     EYMQRRSYLLE"
     gene            1595..1810
                     /locus_tag="KRL22_003719"
     CDS             1595..1810
                     /locus_tag="KRL22_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBH1274142.1"
                     /translation="MEFFNSAIDVLQTLVIALGAGLGIWGVINLLEGYGNDNPGAKSQ
                     GIKQLMAGGGVALIGTILVPLLSGLFG"
     gene            1829..2698
                     /locus_tag="KRL22_003720"
     CDS             1829..2698
                     /locus_tag="KRL22_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274143.1"
                     /translation="MESILEAINEWIKEILIGAINGNLSTMFGDVNEKVGTIAAEVGK
                     TPQGWNANIFSMIQNLSENVIVPIAGLVITYVLCYELISMVTEKNNMHDIETFMFFKW
                     FFKAFVAVFLVTHTFDITMAVFDMAQHIVSGAAGVIGGDTNIDVTEALAAMQEGLKDM
                     EIPELLLLVMETSLVSLCMKIMSVLITVILYGRMIEIYAYCSVSPIPFATMTNREWGQ
                     IGNNYLKGLFALGFQGFLIMICVGIYAVLVGEMVLADNLHSAIFSLAAYTVILCFSLF
                     KSGALAKSIFNAH"
     gene            2740..3144
                     /locus_tag="KRL22_003721"
     CDS             2740..3144
                     /locus_tag="KRL22_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBH1274144.1"
                     /translation="MAYVPVPKDLSKVKTKVAFNLTKRQILCFSVALLMGLPLFFLLK
                     DSAGTSLAAMAMIVVMLPCFLVAMYEKHGQPLEVVVKNIIQTKFTRPKVRPYQTENLY
                     ALLEKQRALEKEVSAIVKRTDKKDAGSRRKQA"
     gene            3092..5521
                     /locus_tag="KRL22_003722"
     CDS             3092..5521
                     /locus_tag="KRL22_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1274145.1"
                     /translation="MSKGQTKKTREAAGNRRKLTRAEKKQIAAVIRQAKGDGKAHTAQ
                     QTIPYLAMYPDGICKVAQHKYSKSIAFEDINYQLAQADDKTAIFENWCDFLNYFDASV
                     NVQLSFINQGSQQEQAARAIHIPPQNDDFNSIRTEYSDMLKSQLAKGNNGLVKHKYIT
                     FSIEADNPAAARARLSRIETDVLNNFKVLGVSAHPLSGYERLKVLHGVFHPAGEPFSF
                     SYDWLTPTGLTTKDFIAPSSFKFGEGRYFAMGKKTGAVSFLEIFAPELNDRILADMLD
                     LETGVIVNLHIRSIDQSEAIKTIKRKITDLDKMKIEEQKKAVRSGYDMDIIPSDLATF
                     GNEAKNLLQDLQSRNERMFLLTFLVVNMADTKRKLENDIFAAAGIAQKYNCALTRLDY
                     QQEAGLMSSIPLGENLIPIQRGLTTSSTAIFIPFITQELFQTGAALYYGLNALSNNMI
                     LCDRKQLKNPNGLILGTPGSGKSFAAKREITNAFLITDDDIFICDPEAEYFALVKRLG
                     GQVIRLSPTGKGMDGTPQYVNPMDMNLNYSEDDSPLALKSDFILSLCELVIGGKEGLQ
                     PVDKTVIDRAVRNVYRDYLADPVPEKMPILGDLYDELLKQPEPEAARIAAALELYVSG
                     SLNVFNHRTNVELNNRLVCFDIKQLGKQLKKLGMLIVQDQIWNRVTINRAEKKSTRYY
                     MDEFHLLLKEEQTAAYSVEIWKRFRKWGGIPTAITQNIKDLLASREVENIFENSDFVL
                     MLNQAQGDRAILAKQLNISPQQMKYVTHTEAGEGLIFYGNVVLPFVDHFPKDTELYRI
                     MTTKPEEVSSL"
     gene            5518..>5861
                     /locus_tag="KRL22_003723"
     CDS             5518..>5861
                     /locus_tag="KRL22_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBH1274146.1"
                     /translation="MKTDVIINRDALCALKELPSESVHCCVTSPPYFALRDYGLDAQI
                     GQEDTPEQYIDRLTSVFRELYRVLRKDGTLWLNIADTYCGTGNKGGYADPKNPKGRTG
                     QRIARNSRVTGC"
BASE COUNT         1651 a         1395 c         1462 g         1353 t
ORIGIN      
        1 acgctgcttg aaatgataaa tgccagtgaa gcccgcgagg acgacccgga atttcagtcc
       61 cccgttgacc tcatgtttga acggttggag gaaaaagacc cggaacactt tgccgtccgg
      121 cagtataaga aattcctgtt atctgcggga aagacaagaa gctctatcct catttcctgc
      181 ggtgcgcggc ttgcaccctt tgacattaaa gagctgcgcg accttatgga aaccgacgaa
      241 atggagcttg acaccatagg cgaccgcaag accgccctgt ttgtcattat cagcgatacc
      301 gacgatacct ttaactttgt agtatcaatc ctttacacgc agcttttcaa tctcctttgc
      361 gacaaggcag atgatgaata cggcgggcgg ctgcccgtcc atgtgcgctg tctgttagac
      421 gagtttgcaa atatcgggca gataccgaag tttgaaaagc tcatagccac tatccgaagc
      481 cgggaaatct ctgcttccat cattttgcag agccagtcgc agctaaaggc gatatacaaa
      541 gataacgctg atactatcgt cggcaactgc gacaccactc ttttcttggg cggcaaggag
      601 aaaaccaccc tcaaagaaat gtccgaaatc ttggggaaag aaaccattga cagcttcaac
      661 acttccgaga accgggggcg ggaggtatcg catgggctga actatcaaaa attaggtaag
      721 cagcttatga cggaagatga aattgcggtc atggacggcg ggaaatgtat tttacagcta
      781 cgaggggtgc gcccgttttt ctctgataag tacgacataa caaagcaccc caactataaa
      841 tacctgtctg actatgacaa gaaaaatacc tttgatatgg agaagcattt aaggcgcaga
      901 cccgcccttg tgaagccgga cgaagtattt gactactacg aaatcagcga aagcgatttg
      961 caggaggaca ccgaccatga ataaacgtat cagaaagaaa aaggacaaga aaatcacaga
     1021 agccataaac gggcttgttt tcattgccga gcgacgggaa cagcaacggc aggcagctat
     1081 ccggcagttt gtgaaacggt gtgaagccct gtatgagcag aaacgggtgc ggcgggaact
     1141 ttgattttac gggaggttac actatgagca gacagaaaac aaaaactgat gatatacgtc
     1201 gtgaacatta ttttacaaag atgatagaaa atgcagaaaa cgctctgcgg gaggatttgc
     1261 aggaacgcgg aggggaacag accctttacg ttaccgagta tatgcagcgc aggagctatc
     1321 ttttggaatg acgaaaaatg tgtgttcccg gctgaaaaga aaggaggaat tgacgcagta
     1381 acaaagaaac agacaactta cagaatacgc gcccctactg gaaaatccat aacgcccaca
     1441 ctcaaaactg aataccgccg cgcggcagac acataggcag cgcggggaac ccgccacaat
     1501 ccggcgggct tatgaccgcg gcagttacaa aactgaccgc cgttttttat gcccttttat
     1561 agggcaagcc gcatttgcgg aagaaaggag ctttatggaa ttttttaact ctgctatcga
     1621 cgtattacag acccttgtta tcgcactggg cgcaggctta ggcatttggg gcgttatcaa
     1681 tctcttggag ggatatggaa acgacaatcc gggtgcgaaa agtcaaggca ttaagcagct
     1741 catggcgggc ggcggcgttg cccttatcgg cactatcctt gtaccgcttc tttccggtct
     1801 gttcggataa agttacggag ggtagcctat ggagagcata ctggaagcga ttaacgaatg
     1861 gataaaagaa atccttatcg gagccattaa cggcaacctt tccactatgt tcggggacgt
     1921 aaacgaaaaa gtaggcacca ttgccgcgga ggtaggcaag accccgcagg ggtggaacgc
     1981 aaacattttc agcatgatac aaaacctgtc ggaaaatgtg attgtaccca ttgcggggct
     2041 tgtcattacc tatgtcctct gttatgagct tatcagcatg gtaacggaaa aaaacaatat
     2101 gcacgacata gaaacattca tgttctttaa gtggtttttc aaagcctttg ttgccgtttt
     2161 cttggtaacg catacctttg atataacaat ggcagtcttt gatatggcgc agcatattgt
     2221 gtccggtgcg gcgggggtaa tcggcggcga tacgaatatc gacgtaaccg aagcccttgc
     2281 cgccatgcag gagggactaa aagatatgga aatccccgaa ctactgttac ttgtcatgga
     2341 aacgagcctt gtaagccttt gtatgaaaat catgtccgta ctgataaccg ttatcctcta
     2401 cggcagaatg attgagatat acgcctactg ttcagtttcc cctatcccct ttgccaccat
     2461 gacaaaccgg gaatggggac agattgggaa caactaccta aaggggctgt ttgcactggg
     2521 ctttcaaggc ttcctcatta tgatatgcgt cggcatttac gcagttttgg taggcgaaat
     2581 ggtcttagcg gataacctgc acagcgcgat tttttccctt gcagcctata cggttatcct
     2641 ctgtttttcc ctgttcaaat ccggcgcact ggcaaaatct atttttaatg cacattaaca
     2701 cagcacacgc gggcaagccc cgcagaaagg aggtttttct tggcgtatgt acctgtacct
     2761 aaagacttat ccaaagtcaa aacaaaagtc gctttcaatc tgacaaagcg gcaaatcctt
     2821 tgtttttcag tggcacttct tatgggactg ccgcttttct ttttgctcaa agacagcgca
     2881 gggacgagcc ttgcggcaat ggcaatgatt gtcgttatgc ttccctgctt cttggttgcc
     2941 atgtatgaaa agcatggaca gccccttgaa gtggttgtaa agaacatcat tcagacaaaa
     3001 tttacccgtc ccaaagtgcg accgtatcag acggaaaacc tatatgcact cttggagaaa
     3061 cagcgggcat tagaaaagga ggtatcagcg attgtcaaaa ggacagacaa aaaagacgcg
     3121 ggaagccgca ggaaacaggc gtaagctgac ccgcgcggaa aagaaacaga tagcggcggt
     3181 tatccggcag gcaaaggggg acggcaaagc acacaccgca cagcagacca ttccctacct
     3241 tgccatgtac ccggacggta tctgcaaagt ggcacagcac aagtattcaa agagcattgc
     3301 ttttgaggac atcaactatc agcttgcaca ggcagacgat aagaccgcca tttttgaaaa
     3361 ctggtgcgat tttctcaact actttgacgc aagcgtgaac gtgcagcttt ctttcatcaa
     3421 tcaaggctca cagcaggaac aggcagcgag ggcaatccat atcccgcccc aaaatgacga
     3481 ttttaattct atccgcaccg agtattccga tatgctgaaa tcgcagcttg ccaaagggaa
     3541 caacgggctt gtaaagcaca agtacatcac gttttccatt gaagcggaca atccggcggc
     3601 agcaagggcg cgcctttccc gtattgaaac ggacgtactc aacaacttca aggtgcttgg
     3661 ggtatcggcg caccccttat ccggctatga acgcttaaag gtgctgcatg gggtattcca
     3721 cccggcaggc gagccgttct cattctctta tgactggctg accccgaccg ggcttactac
     3781 aaaggacttt atcgccccgt cctctttcaa gttcggggag ggacgctact ttgctatggg
     3841 gaaaaagacg ggggcggtat cgttccttga aatctttgcc ccggagctaa acgaccgtat
     3901 cttagcggat atgttagatt tggaaacagg cgtaatcgtc aacttacata tccgcagtat
     3961 cgaccagtcg gaagcaatca agaccattaa gcgcaaaatc actgaccttg acaagatgaa
     4021 gattgaggaa cagaaaaaag cagttagaag cggttatgac atggatataa tcccgtccga
     4081 ccttgccact tttggaaatg aagcaaagaa tttattgcag gatttacaga gccgcaacga
     4141 gcgaatgttt ctccttacgt tccttgtggt aaacatggca gacacgaaac ggaaactgga
     4201 aaatgacatt ttcgcggcgg cgggcattgc acagaaatac aactgcgcct tgacccgtct
     4261 tgattatcag caggaagcgg gactaatgtc ctctatccct ttgggcgaga accttatccc
     4321 tattcagaga gggttgacga cgagcagcac cgctattttt atcccgttca tcacgcagga
     4381 gctatttcag accggggctg ccctgtatta tggcttaaat gccctgtcaa acaacatgat
     4441 actctgcgac cgtaagcagc ttaaaaaccc gaatgggctt atcttgggaa caccgggcag
     4501 tggaaaatcc tttgcagcaa agcgggaaat cacaaatgcc tttctcatta ccgacgacga
     4561 tatttttatc tgcgacccgg aagcggaata ttttgccctt gtaaaacggc ttggcgggca
     4621 agtgatacgc ttatccccaa ccggaaaagg catggacggt acgccccagt atgtgaaccc
     4681 tatggatatg aaccttaatt acagcgagga cgacagcccc cttgcactga aaagcgattt
     4741 tatcctttcc ctctgcgagc ttgtcattgg cggcaaagag ggcttgcagc ccgtagataa
     4801 gacggttatt gaccgcgccg taaggaatgt gtaccgggac tatcttgctg accctgtacc
     4861 ggagaaaatg cctatcttgg gcgaccttta cgacgaactg ttgaagcagc cggagccgga
     4921 agctgcccgc attgcggcgg cattggagct gtatgtttcc ggtagcctta acgtattcaa
     4981 ccacagaacc aacgtggaac tgaataaccg ccttgtttgc tttgatatta agcagcttgg
     5041 aaaacagctt aaaaagttag gtatgctcat tgtgcaagac cagatatgga accgcgttac
     5101 cattaaccgg gcagaaaaga aatctacccg ctactatatg gacgaatttc atctgctctt
     5161 aaaagaggaa cagaccgccg cttatagtgt ggagatttgg aagcgttttc gtaaatgggg
     5221 cggcataccg acagctatca cacagaacat aaaggacttg cttgcttccc gcgaggtgga
     5281 aaatatcttt gaaaactctg attttgtcct catgcttaat caggcacagg gcgaccgggc
     5341 tatccttgca aagcagctta atatctcccc gcaacagatg aagtatgtaa cccacaccga
     5401 agcaggcgag ggacttatct tttatgggaa tgtggtgctg ccctttgtag accatttccc
     5461 gaaagacacc gagctttacc gcattatgac gacgaagccg gaggaagtga gcagcctatg
     5521 aaaaccgacg tgattatcaa cagggacgcg ctttgtgcct taaaagagct gccctctgaa
     5581 agcgtccatt gctgcgttac aagcccgccg tactttgcgc tgcgggacta tgggcttgac
     5641 gcacaaatcg gacaggagga tacgccggaa cagtatattg acaggctgac ctctgttttt
     5701 cgcgagcttt accgggtgct tagaaaggac ggtacgttat ggctgaatat cgcagacacc
     5761 tattgcggca caggaaataa aggcggctat gctgacccaa aaaacccaaa gggacgcacc
     5821 ggacagcgga ttgcaaggaa cagccgcgtt accggctgca a
//
LOCUS       DAEPUT010000148         5752 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.152, whole genome shotgun sequence.
ACCESSION   DAEPUT010000148 DAEPUT010000000
VERSION     DAEPUT010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.152"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            279..2291
                     /locus_tag="KRL22_003724"
     CDS             279..2291
                     /locus_tag="KRL22_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1274147.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLNEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            2660..3880
                     /locus_tag="KRL22_003725"
     CDS             2660..3880
                     /locus_tag="KRL22_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1274148.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            3917..5266
                     /locus_tag="KRL22_003726"
     CDS             3917..5266
                     /locus_tag="KRL22_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1274149.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFVGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPIVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(5398..5691)
                     /locus_tag="KRL22_003727"
     CDS             complement(5398..5691)
                     /locus_tag="KRL22_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274150.1"
                     /translation="MISMIMMLIGVLFIVFGIILTAVEIKGKMPGFYGVGQNAVRKNA
                     IGIIAAGIALIFFRNGLDSIDSILTYGVFLVIELVVIGLYFLIRIKYDKDGNL"
BASE COUNT         2356 a          669 c          829 g         1898 t
ORIGIN      
        1 atattatcaa tagaatttat taaaataaat ttttttgggt gtatattata atttaatcga
       61 atagaaatga aaaatataca tacagtttaa gttttaagca acaattaggg ggatttggtg
      121 acaagatttt taattataag aaagaaagtg tcttaatgca acttttataa agtcattata
      181 gacactttct tttttatttg ataaatttaa attatcaaaa ttatattgct ttatacaact
      241 attttgttgg aaactattta ttatataagg agaaataaat gaaaaaatca gtagctctgg
      301 taaatgatag tagaaaagat ttaatagact ttttagaaaa taatttgaaa ttagtttttg
      361 gagattctat aaatattaat agatacttca taaatgaaat aaatgataat gatattataa
      421 atgatgatgt gatattagta atgtcagtag aaagattaga caaaattata aataatatac
      481 tagataagaa aaaagtgatt gtggtaagaa gaacttttag ggaagataaa atttataatc
      541 tactatcttt accacagggt acaaatgttc taatcgtaaa tgattctgat gaaactactc
      601 tagaaactat aagtttattt tataaaattg gagtgactaa tattagacca attccatata
      661 tgaatgataa taactataaa aatataaaaa tagctataac tccaggagtt ccagaaaaag
      721 tacctagctt tatctcagat atatttgatt taggtcacag atatatagat atctctacat
      781 ttatagaaat aataaattta ttacaaattg attcaaagga aatacaatct aatctagtta
      841 aatactcaga agaaataata agtttagata ctggtataaa agataaatat aaggaattat
      901 ttttaaaaat agaagaatta gatacaatct tgaatttatc aaaagatggt atattattta
      961 cttcaaaaga tggtgaaata aatacatata atagtaaagt aaaagatatt ttagacataa
     1021 atgaggatat atatggaaaa tacattgagg atatatttgt agatagttta aaagttttat
     1081 tgagtgagaa agagatacta gataaagttg tcgtattcaa taagaaatat ataaatgtaa
     1141 ataaaaaaaa catatacaat agagatgaaa aaatgggcac atattatagt ttacaagaaa
     1201 taacatacat aaaaaaatta gaacaaaatc tcactaaaaa attaagagaa aaaggacaaa
     1261 tagcaaaata tacatttaag gatataaaaa caaatagtcc taaaatgttt gaatgtatag
     1321 atttagctaa gaaggtttct aaatctgatt taagcatact tatcagaggt gaaagtggaa
     1381 ctggtaaaga actcatagct cagtctatac ataacaactc aaatagaaaa aatcaaccct
     1441 ttatagcagt aaattgtgca gccgttcctg aaaatttatt agaaagccag ctattcggat
     1501 atgacaaggg aacttttact ggaggtctaa aagatggaaa acaaggatta tttgaacttg
     1561 ctaataatgg aacaatattc ttaaatgaaa taggcgatat gcctttagaa ttacaaacaa
     1621 aactacttag agttcttcaa gaaaagcaga taatgcctgt tggatctcac aatgtaatta
     1681 atatagatgt tagaatcata tctgctacaa ataagaattt agaacaaatg attgataata
     1741 gccaatttag agaggattta tattatcgat taaatacaat tccaataaat atacctcctc
     1801 taagagaaag aaaagaagac atattaatta ttatggaaga tttaattaat aagaaattag
     1861 taatcacacc agaagcaaaa aaacttatac aaaactatat gtggaaaggt aatataagag
     1921 aactccaaaa tgttacatcc tatttaaaca ttatgtgtga agatattgta ttagagaaag
     1981 atttacctcc aaacttaagg tcttcagata acaaaaatac atcattaaaa ctaaaatata
     2041 gtaagaatga tatattgaat atattagaga tactaatttt aaataaggaa tcagatgttg
     2101 gtattggtag aggattaatt ttaaaagcac tactcgataa gaaccttcaa attacagaag
     2161 gaaaaattaa aaaaatattt gaatatctaa aaaaagaaga acttataatt tgtagttcag
     2221 gaagatatgg aagtaaaata actcaaaaag gagaagattt ttacaataaa ttaaaatata
     2281 aaggtctata aaattataat ttatcaaaca aagaaatcta ttcaggatta aagtactcct
     2341 tcaataggtt tttttatttt tcaagtaccc taaaattata atttattttg tacataaata
     2401 ataggaatta ataggaatag gataattttt ttatttccta ttttttttat ataaactagc
     2461 atataaaata tattttcttc aaaataatat tttttactga aaattgaaac tatgcaatca
     2521 ttttttatac tatacatata gataaatgat tatatttatt caatattctt ataaaaaaca
     2581 aaattctcca tcgaaaatta tggcataata attgcttatt atattaataa aacaataaaa
     2641 agcaattgga ggaataaaaa tgcaacaggc tttgaaatta aaatatcaaa ccaaagaatt
     2701 aggaaaagat tttgtaatag aaagttgtaa ttctataaaa ccatggctta taaacataag
     2761 aagagaatta cataaaattc cagaattagc tcttgaagaa aatcttacta aacagaaggt
     2821 aatttcttat ttaaaagaaa tcggaattga ttatatggaa tttacaaaac acaatggaat
     2881 tatggcatat attttaaaag aaagtgcaga taaaacgatt tgtataagag cagatatgga
     2941 tgctcttcct attgaagaag aaaacaacat accttataaa tcaatacatt ctggaaaaat
     3001 gcatgcttgt ggccatgatg cacatacaac catgctactt ggagcatgta aagttttaca
     3061 ttcaataaaa gataaactta atgtaaatgt aaaattctta tttcaaccag cagaagaagg
     3121 ttttggagga gcaaaatttt tagttgagga tgggtgttta gaaaacccca aggccgatta
     3181 tatattcgga cttcatgtta tgccacatat agaaacaggc cttatcgaaa caaaatatga
     3241 tacattaaat gctagtgtag acactataaa aataagtatc aaaggtaaaa gagctcatgg
     3301 tgcatatcct gaaaacggta ttgatgcaat agttacagct tcacaaattg ttacatcatt
     3361 acaaactata ataagtagaa acttagaacc aaataatgct gctgttttga ctataggtaa
     3421 aatatatggt ggtgatgcac acaatgtaat atgtgaagat gtaaaattag aaggcacttt
     3481 aagaacctta aatagcaaaa caagaaactt tatgattgat aaaatagcta aaattgttgg
     3541 agatactgca tctgcatttg gttgtgttgg gactttacat gtaagtgatg aaaactatcc
     3601 tgctgttata aatgaaaaag aattagtaga tacagttata tcaaatacta aagaattact
     3661 tggagaggaa aaatttatat tgagaccaaa cccgtcttta ggtggtgaag acttttcttt
     3721 ttacacagaa cattgtaaag gagcattctt ccatttagga tgtaaaaatg aggaaaaggg
     3781 cttaatttca cctcttcata cctctagctt taatatagat gaagattgtt taccaatagg
     3841 tgttatgatg catgtaatga atactttgta ttttaattag tacagtaatt aataaaagaa
     3901 taggagataa attaatatgg aaaaagctaa gaaattaggt ctatttagta tgatattatt
     3961 agggattaat agcataatag gttcaggtat attcttacta ccaggtaaag tttataatct
     4021 agcaggtcaa aacagtatgt ttatatacat ttttgctaca ctcttagttc tatcaatact
     4081 tttatgtttt gcagaagttg gaagcatgtt tgataagaat ggaggagcat atctatactc
     4141 caaaaaagct tttggagatt ttataggatt tgaagttggt acaatgtctt gggttattag
     4201 aattatatca tggtctactc tagcagtagg atttgcaaca gctttaggtt cattttggcc
     4261 agaatctgcc actgaataca aaggttatat agctgcaata ctcgtaacac tactttcaat
     4321 aaatagctta tttggaatta aaagcacaaa gataatgaat aatgtaataa ctatagctaa
     4381 attagtacca ttaatagttt ttataatagt tggaatattc tttataaaat ttgtaaatat
     4441 tgttccttca ggaaatgtag ttaactctag tatgggtcca gccattatat tagtatttta
     4501 cgcatttacc ggctttgaat catttattgt ggcaagtgga gaaatggaaa atcctaaaaa
     4561 aaatcttcca gtcgcattaa taaccacaat atttatatgt gcaataattt atatattaat
     4621 tcaaattgtc tgtatgggta tacttggaga tagactattt gaaaacagta ttccaattgc
     4681 agatgcttca agtgtatttg taggcaatta tggtaaagtt ttcatatctg tagcaacatt
     4741 aatatctata tttggtataa atataggttc atcaatagta actcctaaat gtggttcttc
     4801 tctagcagaa gaaggttctc ttcctgcatt tataggaaaa acaaataaat atggtgctcc
     4861 atatgtagca ataataatat ctttaatttg ttgtatacca cttgtgctaa ctggaagttt
     4921 tgaacaactt gcagtaatga gcgtaattgc aagatttgct cagtacatac caacttgttt
     4981 atcagtaata gttttaagaa aaagaacaga tgttaaggcc tcttttaaga ttccatttgg
     5041 ccctgttata ccaatagtag ctattttagg tagcttatgg ttgttacaac aagcttgggc
     5101 agaagatatt tcaaaaccta taactcaaaa tagagtttta ataggattag gggcaatgtt
     5161 gttaatagct cctctatata tatttatgaa aaaaaataag gaaatcgagc ataaaaataa
     5221 atcagaagat tctaaattat atatttcgag agaaaaaatt caataatatt ttatactatt
     5281 acttctcata aaatataata aatataaaaa aattgtagat aaaactattt tataaaattt
     5341 atctacaatt tttttatata aacatatatc aaaatcaaaa tattattaat ttatacttta
     5401 aagattccca tctttatcat attttattct tataagaaaa tataatccta ttactactaa
     5461 ctctatcact aaaaatactc cataggtaag aattgaatca atactatcta acccatttct
     5521 aaaaaaaatt aatgctatac ctgctgctat aatccctata gcattttttc ttactgcatt
     5581 ttgcccaact ccataaaaac ctggcatttt tccttttatt tcgacagcag ttaaaattat
     5641 cccaaacact ataaataata ctccaataag catcataatc atactaatca tctaattacc
     5701 tccttcactt aaggaaattt caatttctaa aatctaaaat aaataatatt ta
//
LOCUS       DAEPUT010000149         5683 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.153, whole genome shotgun sequence.
ACCESSION   DAEPUT010000149 DAEPUT010000000
VERSION     DAEPUT010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5683
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.153"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            113..229
                     /gene="rrf"
                     /locus_tag="KRL22_003728"
     rRNA            113..229
                     /gene="rrf"
                     /locus_tag="KRL22_003728"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(443..1627)
                     /locus_tag="KRL22_003729"
     CDS             complement(443..1627)
                     /locus_tag="KRL22_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1274151.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            2000..4351
                     /locus_tag="KRL22_003730"
     CDS             2000..4351
                     /locus_tag="KRL22_003730"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBH1274152.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4373..4912
                     /gene="nrdG"
                     /locus_tag="KRL22_003731"
     CDS             4373..4912
                     /gene="nrdG"
                     /locus_tag="KRL22_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBH1274153.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2217 a          647 c          914 g         1905 t
ORIGIN      
        1 cattcattaa gatatatgtg tagtttttag agtgctaact ctaaagaaac tagtattact
       61 aggttctata aacttattaa aaacttaata gaaatattaa gcataaagat tatgtggtta
      121 caatagcaga gaggatacac ctgttcccat tccgaacaca gaagttaagc tctctagcgc
      181 tgatggtact tggtgggaaa ctgcctggga gagtaggacg tagccacgta atttttttgt
      241 tataataaat ttagaattta acttatatag tttaatttga taatttgatg aaaaaaataa
      301 aagacttact gatttttaaa tctataggtc ttttattttt tatctaacat ttaaattaag
      361 ttgttgaata tatcttatat tacttacctt atatattaat taccattaat acattatatc
      421 taattactat tcatctaaat tactatgcca ttattttata tacaaattct tttaatttat
      481 ctaatccaga taagaaagta ttttcactgc aagcatagga tatacgaata tatttatcca
      541 taccaaatgc tatgccagga acaactgcaa cattatattc ttctaaaaat tgattacaaa
      601 attctataga aaaactatct ttatattcaa atttctcaga tactttagaa agatctataa
      661 atatatagaa tgcgccattt ggattcacat atcctacatt atcaatagag tctagttttg
      721 atttaattaa atctcttctt gatttatatg ttttaaccat attgtctatg tcaattgagc
      781 aatctttcaa ggctccatag gctatgtatt gtgctgttag acttgggtga gatataagat
      841 gtccttgtat agaactcatt gctttagcaa tcgttttatt agatgcagta tatcctaatc
      901 ttaatccagt cattgcagct gacttagaaa aaccatttat agttattgtt atatctttag
      961 cttcttcgct taatgatgca attgatgtaa attcaccagt gtagcatatt ttttcatata
     1021 tttcatctgc taaaatatat attttatttt gtatgcatac atctactatt tctattaatt
     1081 catcttttgt ataaacacta ccagtaggat ttgaaggatt gtttattaca agaatttttg
     1141 ttttatctgt tatagatttt tcaagttctt cttttgttaa cttaaatcca ttttcttttt
     1201 tagtatcaat aaaaactgga acagcattaa ctaacttaat catttcagga taactaaccc
     1261 aataaggctt tggtaataag acttcatctc cttcgtctgt taaagctagt aaagtatttg
     1321 ttattgagtt ttttgctcca cttgatacaa ctatttcgtc tattgaatag ttacagttat
     1381 tttcttcaat aagtttttta cagatttcct ctctaagtat ttttaatcct ggaactaaat
     1441 catatttagt gtaatcttta tttaaagaat caataccata agattttgcg ttattaggta
     1501 cattaaaatc gggttctcct atactaagat ttattacttt aactccatta ctttccattt
     1561 ctttaacttt agaactaata cctattgtgt aggatggtgt tataaagttt agtctttttg
     1621 ataacataaa atgcctcctt ttaaattatt atttatatta tacgacaaat ttaaagaatt
     1681 tacataagga aatttgtaga tatatacatt aatatatata atagcctaca ctttttgcct
     1741 aaaattagtg taaaaaaaag agaaaaaaat tttaactttc aaagttgtta gaaacgctac
     1801 tgttcaaaat atccacatag tatttgcaat gatttgcgca agtttgacta ttatgtacaa
     1861 atttggtaat cttaatatag caattattaa gataatccct ttaacttagt tgaaggggat
     1921 ttttttagac ttaacatact acatatagtg gtatgggaat taataaaata caatatatag
     1981 taacaggagg tttttttaat tggttgaatt tgtaaaaaaa agagatggaa gagtaattcc
     2041 atttaatgaa gatagaataa caagagctat atttttagca gcaacgaatg ttgcagaaag
     2101 agaaggaata gtacctgatt ataaattatc tgagcaatta actcaagaag taataaagtt
     2161 tttaaatcat aaatactcag aatcagttcc aagtgttgaa gatatacaag attctgtagt
     2221 taaggttctt atagaaactg gccatgcaaa aactagtgaa gaatatataa tatacagaac
     2281 tgaaagaagt agaataagaa attcaaaaac aaggttgatg aaggcaatag aggaaattac
     2341 ctttgaagat gcagaagatg ctgatataaa aagagaaaat gcaaatatta atggtaatac
     2401 agcaatggga actatgttac aatatggaag cactgtatct aaagaatttt gtaaaacaca
     2461 tatattaaaa ccagagcatt cttttgctca tgataatgga gatatacaca tacatgatat
     2521 ggatttttta aatatgggaa cattaacttg ttgtcaaata gatgttaaaa aactattcaa
     2581 tggtggattt tcaacaggac atggcttttt aagagagcca caagatataa taagttatgg
     2641 tgcattagct gcaattgcta tacaaagcaa tcaaaacgat caacatggag gtcaaagtat
     2701 accatttttc gattatggat tggctgaagg tgtatataag acatttaaga aattctacat
     2761 aggaaattta gctaaagcat tgaagttatt taaaggaatt gaaaataatg atgtgataaa
     2821 gaacatagta tataatacag agaaagaaac aaatcaaaaa gttggtctta agagagatga
     2881 attgtatcta aacttagaaa aagagaaatt aatacagact tttgatatag atgatgaact
     2941 tgtaaataag atgcaaaact ttgcatttga agaatcgtat agagaaactg ataaaaaaac
     3001 atatcaatct atggaagcat ttatacacaa tctaaacaca atgcactcta gagcaggtgc
     3061 acaggtacca ttttcaagtg taaacttcgg aacagatact tctgaagaag gaagaatggt
     3121 aactaagaat cttctattat ctcaagaaag aggtttaggt aatggagaga caccaatttt
     3181 tccaatttta atatttaagg tcaaagaagg cataaattta aatcctgaag accctaatta
     3241 tgatttattt aaattatcat gcagagtatc agctaaaaga ctattcccta attttagttt
     3301 tttagatgcg ccttttaatg caaaatatta taaaaaaggt gaaccagata cagaggctac
     3361 atatatgggt tgtagaacaa gagtacttag taatgtgtgt ggttcagaaa cagttagtgg
     3421 tagaggaaac atatctttta ctacagtaaa tttaccaaga ttgggtataa aacatggtat
     3481 tataaataat gaaaaggcta atttagacgg tttctttgaa gaattagatg agaagataaa
     3541 cttaattata gaacaattat tggagcgcct tgaggtacaa ggaaataaaa agatgaagaa
     3601 ttttccattc ttaatggggc aaggtgtatg gaaaggttct gatgatttag gaccagaaga
     3661 tacactaaaa gaagtaataa aacaaggaac attgacaatt ggatttatag gtttagcaga
     3721 gtgccttatt gctcttatag gtaaacatca tggagaaagt aaagaagctc aagaattagg
     3781 attaaaaata gtgtcacata tgagacataa aatggatgaa gcaacggaca aatataaatt
     3841 aaatttctcc ttaatgggta ctccagcaga aggtctttca ggtaggttta ctaaaataga
     3901 taaaaaagtt tatggagaaa ttaaaggtat cacagataaa gaatattata ctaattcatt
     3961 ccatgtacca gtttattaca atataagtgc atatgataaa attgagatag aagctccata
     4021 ccatgaattg actaatgcag gtcatataac atatgtagag ttagatggag atccatctga
     4081 taatttagaa gcttttgaaa ctgttataaa agctatgaaa gatttgggta taggatatgg
     4141 aagtataaat catcctgtag atagagaccc aatatgcggt ttttcaggtg taataacaag
     4201 taatatatgt cctgtatgtg gaagaaatga agatgaaagt gacatcaaat tcgaaagaat
     4261 aagaagaata acaggatatt tagttggtac agttgataga tttaataatg ctaaaaaagc
     4321 agaagtaaga gatagagtaa aacatagata gttttatttg ggggaataag ttatgaaaat
     4381 aagaatgtca tctactataa gttatgacag catagttgat ggaccaggat taagaatggt
     4441 aatatggact caaggatgta ttcataattg taaagagtgc cataatcctc agacacatga
     4501 tttatgtgga ggattttata tggatacaga agaaattata aataaagtca aatcattgaa
     4561 attacaaaaa ggcattacgc tatcaggagg agaaccattt ttacaaccag aaccattaga
     4621 agaaatagca agagaagcta aaataaatgg gttagatgta tggtcatata ctggatttac
     4681 gtttgaacaa ctgttagata aaaaaaatag agcgtatttt aaaaatttaa atttactaaa
     4741 gcaaattgat attttagtgg atggaaaatt tatagctgaa aaaaaagata taagcttaaa
     4801 gtttagaggg tcatcaaatc aaaggataat tgatgttcaa aaaagtttga aatataaaaa
     4861 agtgtttttg gttgagcaat atatgaagga tgatttatct atagcagaat aaaatataaa
     4921 taaacaggat taaatatatg catatattta atcctgttta ttttcatata atatttcaag
     4981 cttgtataat gtaacaatta aaccaaaaga ctcattgtat atttgaaatt aagtttttta
     5041 tagtttatag gtgttttatg tggattacga atgatatagt atcgatacat tatttaatag
     5101 attcttatgc caagaaacaa ttaatttata gaaatcctta attgttacaa tataaatatc
     5161 tagataagtt ataagatact gataaataat ttataaagtt tattaatcta atattgtgtg
     5221 tgaatattaa gtggtcaagt agtctaaaaa tgaaaaagat ttaaaaaagt gttttaacta
     5281 aacacataag tgttaaattc atgtataagt ataggttaga tacataagaa ataattatgt
     5341 aatatctatc tttgtaaaaa aatattaaat tttgtaattt gtggataaat atgtttataa
     5401 tgtggataat atttaatgta ataagttaaa gcaatatgaa tcaactgttt ataatgtgga
     5461 taatattata aatgtatgaa taattgcagt atttaaaaac aaaaaaagtt aaaaaagttg
     5521 ttgactctaa aagaaaaagt tggtatagta atacttgtcc tcaagaaaag ggcaaacaaa
     5581 taaagcacaa agaactttga aaattaaaca gtaggttaat ttataaaaca agaaacaaac
     5641 cataaagcca gatattttga taacaatagt atctgagcct gat
//
LOCUS       DAEPUT010000150         5650 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.154, whole genome shotgun sequence.
ACCESSION   DAEPUT010000150 DAEPUT010000000
VERSION     DAEPUT010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5650
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.154"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(79..735)
                     /locus_tag="KRL22_003732"
     CDS             complement(79..735)
                     /locus_tag="KRL22_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274154.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(2008..2418)
                     /locus_tag="KRL22_003733"
     CDS             complement(2008..2418)
                     /locus_tag="KRL22_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274155.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(2634..4016)
                     /locus_tag="KRL22_003734"
     CDS             complement(2634..4016)
                     /locus_tag="KRL22_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH1274156.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVEVGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIEQSGYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(4027..4386)
                     /locus_tag="KRL22_003735"
     CDS             complement(4027..4386)
                     /locus_tag="KRL22_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1274157.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(4591..5370)
                     /locus_tag="KRL22_003736"
     CDS             complement(4591..5370)
                     /locus_tag="KRL22_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBH1274158.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTVISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         1966 a          981 c          490 g         2213 t
ORIGIN      
        1 atttattata aatacaaata atattaattt aaaaagttat tcctaattta aataatacta
       61 ttatcttcat cagtgaatct aaactgcaac tttagactta ttagctaaag ccaatattag
      121 acctaaagct atagatgcaa atgcagaagc aattactcta tactcagcag ggaataagaa
      181 tacaattgta tgacatggta tccagaaaaa tggtatagtt tttaaaacac taaaaccaag
      241 gtaagcattc cagtccacaa tatttaccac atctttaagt tttaccttaa tcccctttcc
      301 aacctcatat tttttatcta taaaacagtc cataacctta tggaataaaa atacagttgg
      361 tgacattagt atattcatag ttgcactctt gaatagagca tttgcaaaag ctattccctc
      421 aaatggaagc ataccatcca cttgtgcttg acctacacct gatgagtaga ttgacattcc
      481 atatgtggta actacaccta ttattcccca aactattgct ctataaaata ctcctactgg
      541 tattttccaa tccttataca aaattctagc accaagtaaa tctcccattg tagctaatac
      601 agcaaacttt aaaaaacctc caatatatgg atgtgcacct gttgcttcca taaatacttc
      661 tctactactt ggtattgcta agacagcaat aatacaaata agaactccac tccatataaa
      721 atcgcctttt ttcatattta taaatactat ttaatatata aatagttctc ctttctatta
      781 aagatttatt taatttacaa tctatctaca attatttatt aatcacttat tattagatat
      841 tcattttcca tatttaaatt tattctatcc ctttatctct ttattttctt actactctat
      901 ccaccattat ctatatattt attttacgat tactctttca ccctaaccct ttaattatct
      961 atttttttct gatattctta tctaccatca tccatatatt tattttacga ttactctttc
     1021 accctaaccc tttaattatc tattttttct gatattctta tctaccatta tctatatatt
     1081 tattttacga ttactctttc accctaaccc tttaactatc tattttttct tactattctt
     1141 atccacatca tccatatatt tattttacga ttactctttc actctaaccc tttaactatc
     1201 tattttttct gatattctta tccaccatca tccatatatt tattttacga ttactctttt
     1261 accctaaccc tttaactatc tatttttttc tggtattctt atctactatt atctgtatat
     1321 ttattttatg attactcttt taacctaccc cctatacttt atagtaatat gtttttaacc
     1381 tttttcatta ttcccaatat gctttataac tacaaatact ctcccccctt aaaaataata
     1441 ataaaattaa tcaataaatt tataatcata ttattactct atgtattaag caattactat
     1501 gccaataaac tttgattttt ttaaacaaat cttaaaaatc ctaaaatgct aattttcttt
     1561 aacttttaat gaatctaata gataacattt aattttcgtt atatttttca gaatatttct
     1621 attattattt ttaagaaaaa aaaataatgt taacattttt taacatacat taaaaaatgt
     1681 taacattata aattgggttt aatactttta ctttgactcg atttactttt attctacttc
     1741 ttactttatt tttaacttag actttatttt tttattactt atttgagtct tatttatttt
     1801 attctcactc catatgttca attacatttg tctaaattct ttgatacttt tattacataa
     1861 ttttaacaag cttaagtgtt atttgggtag tgcagttgat aattatttaa ataatcatca
     1921 actgcatgtt tatatcatta cagtagctta atgtatttaa tcatacttac ttaggatttt
     1981 gaaatatctt agagattata tttaacatta gtcaattgct gcataattgt aagcaattga
     2041 aatttgagac ccatcttcat tttctatagt gataggcttc ataattttta atccttcagt
     2101 ttttatcttt tctaattctt gttccatttt cttaattgtt tcctcaaggt ctttttgact
     2161 tacatctttg actgcattag ggtctttagc atagtctttt aattcttgaa tatgtttagc
     2221 atactcttca taagtataat gctcaacacc atacttttcc aattcagtag ggtcagttat
     2281 tcctgatttt attagagatt caaatttagg taaagcaata ttagatgaat catttccatt
     2341 tgcaaatact gctccagttc ctcctagtac cattgcagat accatcattg cacttataag
     2401 ggattttttt attttcataa ccaatcttcc tttcttagag atttatttgg gtagtgtagt
     2461 ttaaaatgac tattgcaata gttatcaacc acattcttag actatcacag tagtcatgtt
     2521 tatgtcaagc ctttttaaaa aacttttcaa taaaaaatac tatctcaaaa caaaattaat
     2581 tattttgaga tagtatttta attctaaatc ttttatatta ctaagattta tggttactct
     2641 atccatgttc tatattgttc tttattaact gctaacaaat tcccttttct tgatatgaca
     2701 aagcgattat cattatagcc actttgctca attgaaactt ctcctgaatc agtataaagt
     2761 acatccttac tattactaga tttatttaca tacgtttctt cactattctc agaattagtt
     2821 actttgctca tagatgattc ttcatgctct ctaaattcaa ttacagatac ttttgccgta
     2881 ctaaaatgag tctctccatc acttttagct ttactaacaa gaatatcaga ttctactttg
     2941 ggagaatata aatcagttga tttactactt attgaaaatc caattttatc actttgttca
     3001 ttttttgtta aaccaaaaga ttcaacctca ttaatctctt tattttctgt tgcaaaaaca
     3061 agacctgtcc cacaaactaa tacagttgaa actaaaaaag taacataagt tgatttttta
     3121 aatttcataa tattaactat tctcttttct atttttgtct ttccaaatcc actacatatt
     3181 gtcattgaaa atggattatt ctcctctgct agacttatta gtgtggttgc ataatcagcc
     3241 ctatattctt caccaagtat actcataacc ttttcatcac aactaaattc tatgtcttta
     3301 tttagtaaaa aaaacatcac ccaaactaag ggattaaacc aatggacaac aagagctaca
     3361 agcataaata actttaacag attatcaaag ctattaatat gaaccatttc atgagttaaa
     3421 acaaagtcta aagtttgatt attagcataa ttcatttgct ttggcaaaat aattcgtggt
     3481 tttaaaatac cagatgtaag tggtgtccta gtaaattcag atatgcaaac aataaatctt
     3541 ctaaaacggc tattcttaca catccatttt ttaatgaact catgattttt tatatgaatt
     3601 gaagttttaa aaagattaat tattttaaaa tatctaaagc ataaaagtat gctaaacata
     3661 atagtaacta taaaagacaa aatgcccaac atttccaaca tcataatatt ttcaatatta
     3721 gacattattt caaattcgtc agaattgttt ttacctgtag agtcactagc tttcttaaga
     3781 gtataatttt ctgttgatgt attacccact tccacatcaa aagtcgattc aattatacta
     3841 taaatactaa aaccagaatt taaacttact ggtattagaa gtttaaataa aacaatcaac
     3901 cacaataata caaatacctt tttaggtaat tttttaaata aacatgctct tataaaaata
     3961 actattaaaa gtaatactcc agaagtaaaa ctcatttcta acaatttaat gaacataaat
     4021 cttacctcac tttaattttt caacaatttg tttaagtttt gtaatctcat cacttgaaag
     4081 attttcttta ttaataaaag ctgaaagaaa tttttctgaa gaccctccaa acattttatt
     4141 aattaaagtt tctgtttcct gtttttgtac ttcctctttg cttattaaag ctttacaaac
     4201 aaaattcggc tcaattctct ctattgcacc ttttgacact aattttttta taacggtata
     4261 cgtagtgttt ctattccatc ctgtttcttc ttttaaaatt tttactaact ctccagcctt
     4321 gctttctcct ctctcccata gaacttccat tactttaagt tctgaatcaa ataattttat
     4381 ctccatataa aatcgctcct caaatatagt tatcacaata gtcattacta taataaaaaa
     4441 ctatcatagt agtctatact atgtcaatca tttatttttt aataataaaa actgtctttt
     4501 taaaaaattc ttataaaaga cagttttatc aatgttatac tttaatcttt aattaaagcc
     4561 atattttatt taaatatata actatatatc ttagtacata gtataagatt tttctttatc
     4621 taatagtata tcctctacat ctgggttttc ttttactaat tgtctataaa aattacaatt
     4681 agtaacacct acatatggaa ttagccatag tagacctatt ccaagagtag ctattgaaag
     4741 tatataccat cctataaaac taaagtttag tacaaataat ttaagtacat ttcctttcat
     4801 catatctaaa ctagcaccca ttgatttaaa tacacccata ttatccttgt cttcacaaat
     4861 taagaaagta gcttgagaaa catataatag caatatataa accggtaaca taagaacaag
     4921 tattataaga actagagtta ttccagtaga aataacagtc cctattccaa cattatcact
     4981 tgataaatat tcaattgctc cactagtaag taaaactcca aatgataaaa acgctcctat
     5041 aattgtgatt ataaaagaat aaatataaac aataattgat tcaaataaat aaaaaccaaa
     5101 acttcttaaa taaattctcc cacttacaaa gatatctcct atcttgactt tttcatcttt
     5161 agtaattttc aagaacatac atgtaaatcc tgctgaaacg caaaaagcta ttacagccac
     5221 tacaatagta gtcaatggtt caaaaggtaa tcctacaatt gatattaata ctatcaatgc
     5281 aatatatact gccatagaaa ttgcacatat cccccagttt ccagataact gagctttaga
     5341 tactcgtttt aattcttgcc ttgataccat aaaaaacacc cctttcattt tataaaaaaa
     5401 cttttaaaaa tataaataat cttttaacgt ataatattaa tatatcatat tttcgactat
     5461 ataagataca attattcacc atgttttatc aagatatacc ataattgtat tactagtttt
     5521 atatagtcaa cattaccaaa tacatcaaat aaatttgatt aattattcaa caagtaataa
     5581 aataatttct attaattata ctttatttag taaacaaatt atttaataaa aaaattacct
     5641 aatacagtaa
//
LOCUS       DAEPUT010000151         5602 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.155, whole genome shotgun sequence.
ACCESSION   DAEPUT010000151 DAEPUT010000000
VERSION     DAEPUT010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5602
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.155"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(328..1011)
                     /locus_tag="KRL22_003737"
     CDS             complement(328..1011)
                     /locus_tag="KRL22_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBH1274159.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(1187..1777)
                     /gene="zapA"
                     /locus_tag="KRL22_003738"
     CDS             complement(1187..1777)
                     /gene="zapA"
                     /locus_tag="KRL22_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBH1274160.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(1802..4195)
                     /locus_tag="KRL22_003739"
     CDS             complement(1802..4195)
                     /locus_tag="KRL22_003739"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBH1274161.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(4212..5231)
                     /gene="pheS"
                     /locus_tag="KRL22_003740"
     CDS             complement(4212..5231)
                     /gene="pheS"
                     /locus_tag="KRL22_003740"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBH1274162.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(5281..5515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1707 a         1088 c          605 g         2202 t
ORIGIN      
        1 tatatttagt atatttctat taacttatat attgattact gtattttaaa ttcttcaatt
       61 aatttatata ctgcttacta aatttaaaac attttaatta atttgtacac tgtttactat
      121 acttgaaata cttctattaa tctatatatt gcctactata cttaagacat tttaattaat
      181 ttatacactg cttactatac ttaaaatact tctattaact tatatattgc ttactatatt
      241 ttaaattctt taattaatct atacaatatt tgctatatat aaagtatatc aaataacagc
      301 ttcatttttt tgtaaattta cagaaagtta attttcatta aatgaatcat ctttattgat
      361 aaacataatt ccaaagacca ctgccaaaat aaaaaaacat attagtattg atttttccac
      421 gaaaattttt gtaaaaaaag ttcctaaaat agctccagat ataaagaata taataatagc
      481 ataatactgt aaactctttt ttatcataaa aatattctta gtatgtatat aatgaaataa
      541 agtttctgta gcacttctta aatttccagt acacattgtc gttgcaaaac tattcccatt
      601 tacttttcta aaactctcta cttgcattga acaaataaaa gaaatagcaa catttacaaa
      661 catattaaat cttcctctag gaataaatga aacaataagt attgtaatca tttcaattat
      721 aatgataacc tgacgccaat gaatctttgt cttattattt gtaaaatact ttcttatctt
      781 ctcggctata aatacaccta acataaatgc caaaatagga atcaaataat aaaatgattc
      841 ctttacatta ccttctgcta tattaagccc aaataaaact atatttccag tttgtgcatt
      901 agcaaagact ttacctctta ccacataagt ataaatatcc aaaaatcctc ctgttattgc
      961 caacaaagaa cataaaaaga atgattcaga catctgactc ttgcttgtca tatataaacc
     1021 tctcgctttc taatgataga tacaaaatca aaatcatttt agattctatt tttcattgat
     1081 ataaaaaaat tatttatatt taaatattgt ctatatttat acatcattta tatttataca
     1141 ttaaaagaag ctgtctcaaa aaacaagaga cagcaaatct tttagtttat tccacatttt
     1201 ttgcatcatt atttaaccct gtacatttta actgtaaatc ataagctttg ttttgaaact
     1261 cagaagctaa gttttcagct atagtagctc tttcatttgc ttcttcaagt tgagtactta
     1321 actcctcaat cttgttttta taagcatcta actctgctct agaaccttct gtcgtattac
     1381 taagttcgaa tatttcttgc tttttatttt ctataatctc aattaactct ttcatcttag
     1441 tttcagcttc acgattttct gcttcttttt ctgctatcgt aagctttaaa gatttgattt
     1501 ctaattgaag ctcttcatta gatgctccaa ccttcttact caattcttca ttcgctttaa
     1561 tcaacttctc attctcatct gaacattcaa ataaaaggtc tgatatattt aatgcagtta
     1621 atatcgcagc aactgataag ctcaatttcg ggttttgacg tgttatttta tccatttctt
     1681 tgtctacaaa atcagcaata ctaatcataa acttctctga tttgtctcca accattggat
     1741 attcagcgcc atggatttta accattactt tgttcatcct aacctccccc gacattagtt
     1801 gttaatttga tcttaagtta gcatttaatt tttcgcttaa ttcacttaat atcttatcat
     1861 gcaccttagc tacatcttca tctgttagag ttttatcttt acttctataa gttattgaat
     1921 atgcaattga cttgtatcca gcttctattt gagaaccttt gtaaacatca aataacttgt
     1981 agctttctac taatccttga ccattttcct ttattatatc ttctatttgt tttacaaata
     2041 catcatcttt aacaataaga gctatatctc ttgatgtaga tggatatttt ggtaatggca
     2101 cataattctt tgttctatca gaattatcaa atacaaagtc aatatctatt tcagcgacat
     2161 aaactctttg acctagattg tagttttcta taacatctgg atgcaattca cctaatgtac
     2221 ctacatattt attattatac actattttag cacatctacc agggtggaag gtagtattat
     2281 tatcttgagg ttcaatttca taacctttaa atccgacatt tacaagtata gtttctatag
     2341 ttccttttag tgcaaagaag tcaacatctt taccatacat acctacacac attctatttt
     2401 cttccttagg taattctgaa tcttgtggga tgaatatatg tccacactca aatgcagata
     2461 cttcttctat tttatgagat acattagttg ataaaacatc taacatattt ggtattaaag
     2521 tagttctcat tacagaagtt tcttctccta atgggttaag taatttaaca aaatttctct
     2581 ttgcattacc ttctggtact cttatcttat ctactccctt agggcttaca aatgaatatg
     2641 ttaatatttc atttaatcct acagcagttg aattatcttt taaagcatcc atgaattttt
     2701 gttttgaagt tttaattcct gctgtcgtat ttccttctaa ttgtacagaa ggtatattct
     2761 caaatccata aattctagct atttcttccc atacatcagc ttcttgttcc atatctgttc
     2821 taaagcttgg tacatctatt tctaatttat cattagctac caaattacat ttaaactcta
     2881 atgattctaa aattcctaca aactgctcca ttggtacatc tacacctaat aggtggttaa
     2941 ttctttgagg atttactacc aattttttag gttctggttt atttggatat acatctacaa
     3001 caccttttaa aacttttcct gctcctaaca tttcaacaag ttgtgcagct ctatttgctg
     3061 ctatctctgc aagattaggg tctaagtctt tttcatttct tgaagatgct tctgacctaa
     3121 taccaacttt tttagctgtc attcttatgt tttctggttt gaaattggca ctttcaaaaa
     3181 gtacagtctt cgtattagaa gttatttctg agttagcacc acccattaca ccagctaaac
     3241 caagtgattt ttctccattt gttataacta gcatatcttt gtctaatgtt ctctcaacat
     3301 catctaatgt tacaagtttc tctccatctt tagcatttct tactactatt cttccagtct
     3361 ctacttgatt tatatcaaaa gcatgaagtg gttgaccaag ctctaacatt acgaagtttg
     3421 ttatatcgac tatgttactt ataggtctta ctcctgcttc tgtaagtctt ctttgcatcc
     3481 aatatggaga aggttctatt tttacatctg taaccattct agcaacatat cttctacata
     3541 aatctggatt atctatctca actttgaaat ctatctcttc gtcactttct tttacttcga
     3601 tttcaggata ttttactttt gttcctatag ttgcagctgc ttctctagct atacccatca
     3661 tgcatttaca atcaggtctg tttgaagtta attcaaaatc tattaaagca tcttttaatc
     3721 ctaaaacatc ttttatatct tttcctaatt cataagaatc ttcgtggtct aaaatatata
     3781 taccacctct tttatactcc tcaatgtaat gttcatctat acctagttca gctgctgaac
     3841 acatcatacc atctgataat tcacctctga aatcagtctg tttgatttca actcctccag
     3901 gtaacttaga accatttaca gctactggaa tataatctcc ttctgatata tttgtagctc
     3961 ctgtaactat ttgaacaact ttatctccaa tatctacttt agttacaacc aacttatcag
     4021 catttggatg ttgttttatt tctaaaatct ttccaaccaa tatattttct atttcttcac
     4081 cataataatc tattgtttca actttagttc ctgtcattgt cattttatca gcgaactctt
     4141 ttacatccat gtctatatca acatagtctc taagccattt taaagatact aacatctaca
     4201 taccctccta attaaaattg atttaagaat ctcatatcat tttcgaataa taatctaata
     4261 tcatctattt catatttaag cattgcaagt ctttcaaccc caactccaaa tgcaaatcca
     4321 ctgtaaactt ctgggtctat tccacaattt ctaagcacat ttggatgaac catacctgaa
     4381 cctaatattt ctatccaacc ttcatattta cacattgggc aacctttacc accacatttg
     4441 aaacaagtaa catcaacctc tgcacttggt tctgtaaatg ggaagttgtg aggtctaaac
     4501 ttagttttga tatcagaacc aaacaatttt tcaacgaaga tatccatagt tcctttaaat
     4561 tctgccatag taacatcttt tccaacaaca agcccttcta tctgatggaa cattggtgag
     4621 tgtgtagcat ctggcgagtc tgacctaaaa catctacctg gtgcaattac ttttattggt
     4681 aactcttgac ttctcatagt tcttacttga actggagatg tttgagttct aagtaatact
     4741 ccatcattga tatagaaggt atcgctcata tctcttgatg gatggtcttt aggagcgttt
     4801 aatgcgtcaa agttgttttc aacagtctca acttctggcc cttctgctat agagaatccc
     4861 attccgataa atatatctgt tacttcatct ataatttgag ttattggatg cttcttccca
     4921 acctttaaaa cttttcctgg ttgagtaaca tctatcactt cctcttttaa ttttctttct
     4981 ttttcaatag catttatttc ttctttttta gaatttatgc taagttcaat gttttctctt
     5041 acctcattgg caaccttacc aactactggt ctttcttcag cagataattt acccatttct
     5101 ttaagtatgg cagttatctc accttttttt cctaagtact taactcttaa actttctaca
     5161 ctttctatgc tttgtgcttc ttttatttca gccaaagctg cttcacgtaa agcaagtaat
     5221 ttttcttgca cacatatcac cctttcgttt ttttgtataa aaaaagcccc tcaatccctg
     5281 tctagggacg aaaggctata gtttcgcggt accaccctag tagtttaaca atttaaaaat
     5341 catcaaacca cctctaacaa acttaacgcg tttttgacgt caaagcctac tgtaaaattt
     5401 cagctctgtt actccagagg gaacttctca tgacctctta gaaaacactc ccagcctagg
     5461 tgtttatctc tttactaagt ttaatcaaaa tactttcctc tttcattgca tttacaatat
     5521 tatattgttt attttagtat tatatcattt ccattcaaat tatgtgacta tttttaatat
     5581 atatccaata tataattaat tt
//
LOCUS       DAEPUT010000152         5529 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.156, whole genome shotgun sequence.
ACCESSION   DAEPUT010000152 DAEPUT010000000
VERSION     DAEPUT010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5529
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.156"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..714
                     /locus_tag="KRL22_003741"
     CDS             <1..714
                     /locus_tag="KRL22_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1274163.1"
                     /translation="VKVRDKQVPKGRILNATISKEPSGRYYVSLCCTDVDIEAFENTN
                     NHIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLVKLQSELSRKTIGSLNRNKARLKV
                     ARLQEHIANQRKDFLQKLSTKLIKENDIICIEDLQVKNMIKNHKLSRSISDVSWSEFI
                     RQLEYKANWYGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDI
                     NASINILKEGLRLITIQNK"
     gene            841..2010
                     /locus_tag="KRL22_003742"
     CDS             841..2010
                     /locus_tag="KRL22_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBH1274164.1"
                     /translation="MNELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQQEEEVAKWV
                     REILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALKDLGIDAQIY
                     FSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGGTTSDLGVLY
                     NGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPESVGYRITEDA
                     IIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLEDAVDQMKTSQ
                     DDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVEKVYSLDKMS
                     REDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVKVVGDLI"
     gene            complement(2173..2715)
                     /locus_tag="KRL22_003743"
     CDS             complement(2173..2715)
                     /locus_tag="KRL22_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HBH1274165.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(2863..3147)
                     /locus_tag="KRL22_003744"
     CDS             complement(2863..3147)
                     /locus_tag="KRL22_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1274166.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(3210..3974)
                     /locus_tag="KRL22_003745"
     CDS             complement(3210..3974)
                     /locus_tag="KRL22_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH1274167.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(4256..4522)
                     /locus_tag="KRL22_003746"
     CDS             complement(4256..4522)
                     /locus_tag="KRL22_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH1274168.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(4564..5373)
                     /locus_tag="KRL22_003747"
     CDS             complement(4564..5373)
                     /locus_tag="KRL22_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274169.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTIIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
BASE COUNT         1955 a          735 c          792 g         2047 t
ORIGIN      
        1 gttaaggtaa gggataaaca agtacctaaa gggagaatac ttaatgctac tatatctaaa
       61 gagccaagtg gtagatatta tgtatcatta tgctgtactg atgtagatat tgaagcattt
      121 gaaaatacta ataatcatat aggtttagat ttaggaatta aagaattttg tatctcaagt
      181 tgtggagaat ttatagaaaa tcctaagtat cttaagaagt cattaaacaa acttgttaaa
      241 ttacaaagcg aattatcgag aaaaacaatc ggtagtttaa atagaaataa agcaagatta
      301 aaagttgcaa gacttcaaga acatatagct aatcaaagaa aggattttct acaaaaacta
      361 tctactaaat taataaaaga gaatgatatt atttgcatag aagatttaca agtaaagaat
      421 atgattaaaa atcataaact atctcgctca atttctgatg tgtcatggtc agaatttatt
      481 cgtcaattag aatacaaggc taattggtat ggtagacaaa ttgtaaaggt aggtaaattc
      541 tttgcaagtt cacaaatatg caataaatgt gggtataaaa acgaggaagt gaaggactta
      601 aatataagag aatggatttg tcctagttgt aatgaaactc acgatagaga tataaatgca
      661 agtataaata tattaaaaga aggattaaga ctaataacaa ttcaaaataa ataacgtatg
      721 taagaaccgt aggaactacg gggatagcct gtggagaatt agtaagacat attttagtat
      781 gcaaaattct gtgaagcagg aaccctgtga ctttagtcat gggaggttca gggtagaaag
      841 ataaatgaac tttgtaaaga tgaagttgta gagttttgca atagaataaa aggtaaagtg
      901 gaaagtgttg caataagtgg agtatttgct ccagtaaata aacaacaaga agaagaagtt
      961 gcaaaatggg ttagagaaat tttaggggat attcctatat ctttatcaaa tgaaataggt
     1021 aatataggta tattagaaag agaaaatgga gctattttaa attctgcatt gtctcaagta
     1081 ggtaaagctg tatctttagg atttgaaaaa gcacttaaag acttaggtat agatgctcaa
     1141 atatatttca gtcaaaatga tggaacatta atgaatttag agtatacaat gaaataccca
     1201 atttttacaa ttggatgtgg aataacaaat tctataagag gagcttcctt cttatcaaaa
     1261 gtaaaaaatg caatagtatt agatgttggt ggaactacaa gcgacttggg tgtactatat
     1321 aatggattcc ctagagaatc atctattcca gttacaattg gaggagtaca tacaaacttt
     1381 agaatgccag atgttttaac tattggtctt gctggtggta catgtgtaaa aggcgaaaaa
     1441 gataatataa agataggtcc tgaaagtgtg ggatatagaa taactgaaga tgcaataata
     1501 tttggtggag acactctaac tttatcagat gttgttacaa aattagatat ggcgtttgaa
     1561 gatagaaaaa gcaatgttga aaacttagat aaagagtatt gtaatgaggt atataagaag
     1621 gttattttaa aattagaaga tgctgtagac caaatgaaga ctagtcaaga tgatgttgaa
     1681 ttggttttaa ctggtggagg aagtataatt gttcctgaaa aactaaaagg cataagcaat
     1741 gttataagac ctcctcatta tactgctgca aatgctattg gtgcagcttt aggacaaata
     1801 agtggagatg tagaaaaagt atacagttta gataaaatgt cgagagaaga tgccatagaa
     1861 gatgcaaaaa aagaggctgt aaataaagct ctaaaagctg gtgctaaaga agatactata
     1921 gaagtattaa atatagaaga tgttccactt gcataccttc ctggtaatgc acttcttata
     1981 aaagtaaaag ttgttggtga tttaatttaa agaataaata taagtatttc cagaattata
     2041 taaatatttc tggactcatt tttaaactta ttttatcaat aaaaacagca taacttttga
     2101 ctatattctt ataagtttcc gaacagccga tatataccta ttttttgagg tttatcggct
     2161 gtttgttatc ttttatcgca ttccaactat ttttcttacc gtatttgctg tacgaattgt
     2221 aatcttatca cttacatttg aactggcagt ctttgaccac caatttgtct ttttataatc
     2281 tttacgacta aaagaccaaa agatagcatt tttataatga tatacttttt catactcttc
     2341 tttaggattt ccaacctcat cataaaactc gtcataagat aagtcaggaa acataaaaat
     2401 aagattatca tatatttctt tgttgttatc tccccaccaa ttaggagcat tatttagtat
     2461 atcttttaac tcttcttgtg aaataataaa aactggtatt tccaattcaa actgtttttt
     2521 tatcattaat cttattgtat ttgagataac cttgctgtca tctacatcac ttaaaaagac
     2581 aacattacca ctattaaggt atgtagaaac ttctgaataa ccaagttcta caaagcttgc
     2641 ttttaattca gacataatta tcttgttctt accacttata ttgatacctc ttaataatgc
     2701 gatataactt ttcatataat aatttcacct ctaaacattc acatttttct atgtagtaca
     2761 aactggaatt tgcatctttt ataattcttt caaaacttct tcatatgtaa tttttttaat
     2821 ataaaaaaat cggtgcttaa tttgtaccga tttttgtttt tcttagtaaa gaactcgttt
     2881 ttttgcttct gctatagctc tagcagcact ttttgcttgc attctttttt cttcttcttt
     2941 tttaaattca tttattgttt catttagatt cttatcatgt tcattttttt ctttatcttc
     3001 gttttctctg tatactaata tataatctat tattgattcg tttattattt gagatatact
     3061 tttattttca ttaattccta ttctcttaac ttccttaagt agagtctcat caatatgaac
     3121 cgttgtttgc tttgtatttt ttgccacctt aatcacctct taaaaaaaat tctaacatta
     3181 aaattttttt tagtcaataa attttaatat taaaattctt taaatgtttt atttgatttt
     3241 ctaaaatttt ctattgtatt tatcatctta ttttttatat tttcacctag tacagaagac
     3301 tttagtctag gattttcgat atggtcataa attggttcta aaaattcgac ttcgacagga
     3361 acagagttaa ttttaccaat aggttggtat ccttcataag tatcttttga attttttatt
     3421 actagtggaa caatagggca ttttgcttta tatgctatct ttaaagctcc acttctaaac
     3481 tccgaaacca atgaatttgg ttctttaatc catgttaaat ctccttctgg aaacactgcc
     3541 atactttgac ctgtaagtat attttgagag gcttgggcta tactctttat accctcacga
     3601 ttgttttttc tgtttacata tacacatctt agtaattttg cccattcttt aaatataggt
     3661 atatttctcc aaactggttc atctgcaatt acacatccaa ttggtctttc tacacttgct
     3721 gttagtatga agctgtcaag catactagaa tgatttacaa caaatagaag tggttctttt
     3781 ggcagtgttt ccttaccaat tatattaagc tctatgttca ctatatctaa agatttttta
     3841 gcttgttttt gcataaattc aaatttttcc tttaagctaa atttatcagg attcttttta
     3901 attttaataa gcctaggtat agaagatgta aaacctataa gttgatatgt agcaaatttt
     3961 aagtaattat tcataaaatt atctccttaa aataaaatta tttattactg taaagatttt
     4021 aacataaaat aaaatttaag tctattttaa ttcaattttg taacatatat tttaaataga
     4081 cagagattga gattttatat ttccaatttt agtaatcaga ttttatcaat aaattactat
     4141 tctattaatt taattaaata acctttaaat ttaattataa aaactgttgc agaaatttct
     4201 acaacagttt aaaaaattta ccttacaaaa acttatttta taacaagaga gtatattata
     4261 aggctagtac agcccatttt ttgcactgag aaattctttt gccatcatca ccttgttctt
     4321 tgtcatatgc aaattgatta agcatttcac atggaaatgt atcacataga ccacaatgtg
     4381 taaggttttt atcttcacaa caagatttta caggacattg ttcaccccaa aatggtttct
     4441 caatctctgt acaaccttta caattgactt tttccttgta tccacattca taacataaaa
     4501 ttccacatct tgattctatc attttaagtc actccttaaa tataaatttt atatgattgt
     4561 atatcaaaat ttatactttt cattgtaaaa atcggacaaa ttttttatat aggttgttgg
     4621 attaacacca caaatagatt taaaatcatt tataaaatga gattggtcgt aataaccaat
     4681 atcttgtgct aaagttgcaa agggtatttt attattttgt atttcttgta atacaaggtt
     4741 tatacgaagt aatctaaggt atgatttaac actcatacca agagaattat taaaaattct
     4801 atttaaatgt cgttcactat aacaactaat ttgtgaaatg tttttaacag acataataga
     4861 gttctgtttt ctagcatttt caagaattgg tatagtcata tctactatat ttgatttcaa
     4921 taagtatgat aagaataaca tatctaattg ttctactaat tcctttatag tacttgttct
     4981 ttcaaaaatg gaattaacct ctaagctaaa taatgtgtta aaatcttcaa gtgaaatttt
     5041 taaatctgta gattctcttt gagaaagacc tgtcaaataa tatactccac ctgggcgaaa
     5101 ctcaacgaat actctaaaaa gtacattttc tatatcattt tttacaataa tagtttttgt
     5161 tgtggctccc cagaatgcgc tttctatacc ttttttgtca aatttaaata tcatacatcc
     5221 actagcatca ggtattaatg taagattttc tttaatactt gtatctggaa tagatattgt
     5281 atagtgtgct atatactgtc ttaacaattt atgtggcaaa atatatgtat actgtttgca
     5341 ggtatttaaa atgttattga ttattttatt cataagtata tcctcctgat atataaaaaa
     5401 taagtatact aatttatttt ttatatgata aagcagtttt gttttaattg aaatattcta
     5461 ataagatatt ttgttaaatt tagatacaat aattgtaaag taaaatctca aaatatacaa
     5521 ttattataa
//
LOCUS       DAEPUT010000153         5511 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.157, whole genome shotgun sequence.
ACCESSION   DAEPUT010000153 DAEPUT010000000
VERSION     DAEPUT010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5511
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.157"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            477..956
                     /locus_tag="KRL22_003748"
     CDS             477..956
                     /locus_tag="KRL22_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1274170.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            953..1732
                     /locus_tag="KRL22_003749"
     CDS             953..1732
                     /locus_tag="KRL22_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274171.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMTNNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANDVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNKFKFLTWKQDGVYYSFTVQDSNLSMNDLIKMAHEVIDAK"
     gene            complement(1982..2482)
                     /locus_tag="KRL22_003750"
     CDS             complement(1982..2482)
                     /locus_tag="KRL22_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1274172.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(3093..3800)
                     /locus_tag="KRL22_003751"
     CDS             complement(3093..3800)
                     /locus_tag="KRL22_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1274173.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            complement(4569..5438)
                     /locus_tag="KRL22_003752"
     CDS             complement(4569..5438)
                     /locus_tag="KRL22_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBH1274174.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITSEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
BASE COUNT         2041 a          817 c          567 g         2086 t
ORIGIN      
        1 gtttatttat gttcatctct atctaaaata atgacatttc taactcttaa ttctcattta
       61 agtttcattg ttttttctta aaagcctact tttagtcaag atactgttat ctttactcat
      121 tatttaaaga acttatttta aatctgtaca tgaagtaaat aatccaaaag cattgttatt
      181 ctaactactc aacattaaat acttactatt ttctaattac tcaatataaa gacttactat
      241 aaaactaaat acataaatgg cttctaaagt ttaatatatc tacatggctt tatatatgac
      301 aggaaaaata ctagaaaaaa tatattatag aatacttgta tataataggc aaaactttca
      361 aacttaaatt tatcaaataa tcataaaaaa agtgaaccat ctatagtaaa attttatcta
      421 ataagtgaaa ggcaaaaaag tagcgctacg atttgcatag aagggaagga acttagttgg
      481 ataaaactac atttacaaac aatatacttg aatcagaaca gactttgtat cgagtatcta
      541 agtctattct aggaaacgac caagactgtg aagatgctgt caacaatgct attttaaaag
      601 catatgaaaa gttggattct cttaaggaag aacaatactt taaaacatgg ctgattagaa
      661 tagtcataaa tgaatgtaat tcattaagac gcaaacgatt aaaatctcta tcatttgaag
      721 atgtcttcaa aaacaaaaaa attgatgaaa aagatgacta tagcgatttg tatactgcta
      781 ttcaaagtct acctaaaaaa attaaaattc caatagtcct ttactatatt gaaggttatt
      841 cagtagatga agttaaggaa atattagata tacctcaagg aactgtaaaa agtagattat
      901 caagaggaag aagattatta aaaactaaat tagaaaacac ggaggtaatc atatgaataa
      961 aaatatatta aataattcgt ttccagaagt tccagaaagt tttcataata gtttaagcaa
     1021 aacactaaat agtttaccag aaagagagga aaattataaa atgactaata ataaaacaca
     1081 caaattacca tttagaaaag gcttagttgc aactttagcc attactttga tattgagcac
     1141 aacagccctt gcagtaggac atatatatag tttagttgga aaatcaagta ctaaggctac
     1201 ctatacatct atcccaacta cagaacaagt aaaaaaagac tttaacttta cccctaatat
     1261 agtttctgaa tttagtaatg gatataaatt taaaggagca tatactgtaa ataaaaaagc
     1321 atttgacaaa gaaaataatg ttttaggaaa atcaaaagca cttagttttg aatataaaaa
     1381 tggcaatgat gaaatatctc ttgacacagc aaatgatgta cttgggaaga gttctgacaa
     1441 tctaaaagtt gtagatactt acaaagatat taatatttct tatgaagcat tcgcacaaaa
     1501 gtttgtacca gaaggttata aaatgacaga acaggataaa attgatgaaa aatcaggcaa
     1561 atacacattt agtgtagggc caaataatga atcagacaaa gttgaagtta ataaatttaa
     1621 gtttttgaca tggaaacaag atggagttta ctattctttt acagttcaag actcaaattt
     1681 atctatgaat gacttaatta aaatggctca tgaagtaata gatgcaaaat aaacataagt
     1741 aataataagt tgtttatgag tttattattt atgactttaa tttttttatt agtaaacatg
     1801 gttgtatctt ccatctttat attttcttta aatttaatat ataaaatttt agatatttag
     1861 ctaccttcaa aagaaccatt attaaaaagc ccttaaaaat atttctttta tatggaattt
     1921 caagggcttt aactttattt tatacaagtg tatatggaat tttaaagact ttaactttat
     1981 tttatataag tgtaagctcc atttgaatta cttcttcttt tacaggtcta tcattccatg
     2041 taaaaccact agatattgta tttacctcta caaaccctaa agatttataa acatgaatag
     2101 ctctactatt acttttaaat acatcaagct caattttttc atacccatat tcttttgata
     2161 aatcaataat ttgttttaaa agactacttc cgataccttt ttccctatac tctttaagaa
     2221 tacccatgcc taaataacca actttttcag ttttaggtaa aacgtcacac caaccaatac
     2281 agttatctga ttctaaatca attataaaca gttgtggtaa gtttttattt ataatatttt
     2341 ttataaattc aactgtttct tcaaaaggaa aggcttcatc catagctaga tatttcctct
     2401 cttttgctat tttatcaaaa gtttgccaat acgaataaat atacttttct tctgccttta
     2461 taaattttat gccttctatc aacttaacat ttcccctttt taatttttga ttgtagttaa
     2521 cttattttat atgattctat tttataatgc tatataaatt actatatatt agcttaaaat
     2581 atctttgtat atttctataa aattaaaacc aatatatcta tctcttgtat ctctattaaa
     2641 ataattttta atagtataat aaatatagct ctttaatctt ttgggtatat atacttaatc
     2701 attttgaaat ttgatttaaa gtataataaa atatataaaa aaatatataa aatggtacta
     2761 taaaattttt aatcttcatc aatacctttt ttgctttcat tgttaaaact attttttcta
     2821 ttagtttatt tcttataaaa caaacattta gtattaaaat atatatcaca caatagtatt
     2881 tgcaatttaa ctttaaaaaa taaaaatacc caactgacct aagcaactcg attgggtata
     2941 aataatctaa aaaatcattt ttgtataaac tctttattta acttacattt ttatttacct
     3001 tctactttaa ttcaacttat atttctatgc ttcttatact ctcattcaac ttatatttct
     3061 acttatctta tacttttata aattcatcac aattatttag ttctcgctat caaagaaatt
     3121 gtattaaaat actttccatt ctctacttcc atcatttttt tgtcatttat agcatatgaa
     3181 ttatcacaat ttatccaatc cttccaagct tcatcatgac aatttaaagc ttcacatttc
     3241 tctacaatca cagactccga ttcagaccaa agtttattcc accatgtaat tgaatggaag
     3301 ttcatattat cttgccaaaa tggaatgagt tcatctggta tacaatccac gaaatcttct
     3361 tttaatccag gcattgccat agcaagtatt cccccctctt ttacaagagg tgatatatga
     3421 ttgtctaaaa atccttcttt gtttccaaaa tagtgataag aatcgatact tatcaccgca
     3481 tcaaagaaac cttctgcata aggtagttca tgtgcctctg cctgtattgg aaatatttta
     3541 tcatccaatt taaactcttt aaatctttta tagttttcag ttggttctat ccataaatct
     3601 gttgcaaata cagtagcatc aaattccttt gctaaaaata tcgaagatat acctttacca
     3661 caacctaagt ctaaaatacg cattcccttt tctagtttta tcttacttgt taattcttcc
     3721 aatattttta tacaattagg tcccatcata tttttcatga gaaagtcctt atcgtattta
     3781 ttactttttg taaatatcat tctatctttc ctttccctat cagttattat ttattaaatt
     3841 ttatacgttt gattttttat tttttatatg cttcttatat tgagcaatct cttttttatt
     3901 cattctttaa taggcaattt taatgtgtaa ttttatccac tctgtgatag taactttaat
     3961 gaataatctt atctagtgtg atagttattt tagtgagtaa ttttatctac tccacagtaa
     4021 tcgctttaat gagtaatctt atccactcta tgatagctat ttttatggac aattttatct
     4081 actctataat atagtcactt taatgagtaa tcataatttt tatatcattt tagatactta
     4141 ctctaataag aagtcatttt ctaatactta ataagtttta attacttcca ctttaaccta
     4201 tatactaatt aacttattta atttagtgca tatttgacac tttacctttt attataccat
     4261 ttattatcat aaatataata attctatttt tttaaaataa atatttataa taatctaaaa
     4321 taaatattta taaattctaa tcaatcctaa ataataatct aaaatacatc aaaaaataaa
     4381 ctaaaaaata tcgaaaaata atttaaaaga catcaaaact aaatcttcta atcagcaatt
     4441 aaaagtctat tttcttagtt taaaaaataa agatagattt tttcaaaaca ctggataaat
     4501 aggtaaaaaa ataaacagtt agtaaaataa atttttacta actgtttatt tttattgttt
     4561 aatatgtcct ataaatcctc taagtaatat tttccttgca aaaattctga ttctaaacct
     4621 agatttttaa aataatcgac catgcccata cacgcaaatt tttctgtaga ataatgagta
     4681 gcacctataa cattaattaa attatctttt gctatttgat ggaactctaa tactggttca
     4741 aaatgtttta aaggcttagt aaacccagta atatatagat ttataccaag ttcagcaact
     4801 tctcttgcta caaatggata acttcctccc cctgctgcaa tagcaactaa accatctttt
     4861 aatacagaat ctccataatc atacaatttc acatcatgac caacagattt tttaattaat
     4921 tccttaatct cttctattga ttttagtgat gttttacata taactcctac ctcaatttta
     4981 tcgtcatatt tacaaaatgg tttgactatt tctaaaccca tagcttttgc aaaactaaca
     5041 gaagttgaat agtcactata gttgtctagt ggagaatgta atacataaaa agaaattcta
     5101 cgatttttca tctcttccat ataagatagt ggtatgtcgt gaaatggaaa accttcatct
     5161 gatgctatgt atcccattgc atgatgtgaa aaaattaaaa tatctttttc atctttatct
     5221 ataacctgct taattatttc tttatcagga aaagtagttg tgtatacttt attaatattt
     5281 tgagcattat ctaatactaa tcctatgtat ttttttctaa attctgaagt gataaaatca
     5341 ttttcaaaat tcataaaact ccaatcatca ttaatatttt taatattaaa ttctaaatct
     5401 aattttttat aaagttcaat tgccttaata ataaccactc ctttataata atattgaatt
     5461 actacatatt aatatagaaa tttccgataa taaactttat acgtttaagt a
//
LOCUS       DAEPUT010000154         5427 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.158, whole genome shotgun sequence.
ACCESSION   DAEPUT010000154 DAEPUT010000000
VERSION     DAEPUT010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5427
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.158"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            366..2237
                     /locus_tag="KRL22_003753"
     CDS             366..2237
                     /locus_tag="KRL22_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HBH1274175.1"
                     /translation="MNRKNLSVIMATAMISTSVAPVFAAETTHVKKETITKKEATELV
                     SKVRDLMSQKYTGGSQVGQPIYEIKIGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKSKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTETVTSKTIYLGIGDEKVDLTANPVDSTGTNLDPSAEGFRVNKIDK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISA
                     KDSETGKYKFTIKYTDASGKAIELTVESNNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIIIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNIERLAGDDRHTTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            2344..3051
                     /locus_tag="KRL22_003754"
     CDS             2344..3051
                     /locus_tag="KRL22_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH1274176.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     VRKVLDDGGSCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAREIILKYLEEYPDAKVKTVTPFKASGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDELAINKIQYVHAP"
     gene            3084..4910
                     /locus_tag="KRL22_003755"
     CDS             3084..4910
                     /locus_tag="KRL22_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH1274177.1"
                     /translation="MKISKKIVSLLTMTFLTVTLYGNTSNASTKDTLTGSGRWETAIK
                     ISQAGWTKSESAVLVNDNSIADALSATPFAKAKDAPILLTQSNKLDSRTKAELKRLGV
                     KNVYLIGGSIALNSEIEKQLNAENINFERISGNSRYDTSLKLAEKLDREKSISKIVVV
                     NGEKGLADAVSVGAIAAQENMPIILSDSENGTEVADNFIDSKDIAKSYVIGGTYSISN
                     SVERSLPNATRIAGSSRSETNAKIIEEFYKDTHIKNIYVTKDGTKNKNDLIDSLAVGV
                     LAAKNSSPILLAGNKLDTTQKNVLNTKIIDSVIQVGGLGNEESVKNIVDMQEKTKYIV
                     ETVDELYVAVKKADANDVIEFKPKKEVSDSIDIETSKAISINFEGVYNQSITIDMPNS
                     EIKNIGKIKDTLQIKNIKSSTLINEGTIDDLDIYDENGCRIENESSGEISLITILKDA
                     KNVYIINEGNITKILNNCNDVVVRNSGKIDIVSGSEQPAISGKKPNINDTEDEEELAR
                     GLNVKSEACSSPRKNYVDITILSNLTSSKYELYYRIVNYKPSARYVGQQINTSDWEIV
                     PVYGSKFTKRVKNGSYIEVVEVKNSTNEISRWGRSNITDDGF"
     gene            complement(4955..5350)
                     /locus_tag="KRL22_003756"
     CDS             complement(4955..5350)
                     /locus_tag="KRL22_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBH1274178.1"
                     /translation="MILKKHRETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFGSKRIEIKFLFKEFLSFVSFRLLSGVVEMLIMYVMIDLLF
                     VNDVIVKIFTNIVVIVLNYLFSKMIIFRK"
BASE COUNT         2300 a          604 c          944 g         1579 t
ORIGIN      
        1 gaaataaaat gtaaaatata gtaatatatt tttttataaa tgaaaaagaa gctgattgac
       61 agcttctttt tctatgtgag aaatacggaa aaaagagatg cttgaaattt ctttcttcca
      121 tttaatatta tactataaag ataataaaaa gtctattagt tataaacggt attataaaaa
      181 aaaattacag ttttgttact tttttgtata catatataaa taaaatatac tttcataaga
      241 ttagttttgt aaaatagtta aatattacgt agatctagtt tattgaaata atatcaaata
      301 tatattataa ttggtaaata aggaaaaaat aataaaaatt tgaatttttt tagggggaaa
      361 ataccatgaa tagaaaaaat ctttctgtaa ttatggctac tgcaatgata agtacatcag
      421 tagctccagt ttttgctgca gaaactacac atgtaaaaaa agaaacaata actaagaaag
      481 aagctacaga actagtttcg aaagttagag atttaatgtc tcaaaagtat acaggaggtt
      541 ctcaagttgg acaaccaata tatgaaataa aaattggtga gactttatca aaattaaaaa
      601 taataactaa tatagatgaa ttagagaaat tagtaaatgc tttgggagaa aataaagaac
      661 ttattgtaac tataacagat aaagggcata taacaaatag tgcaaatgaa gtagttgcag
      721 aagcaactga aaaatatgaa aattcagcag acctttccgc tgaagctaac tctataacag
      781 aaaaatctaa aactgaaact aatggaattt ataaagttgc agatgtaaaa gcttcatatg
      841 atagtgctaa agataagtta gttataactt taagagataa aacagaaaca gtaacttcta
      901 aaactatata tttaggtatt ggtgatgaaa aagttgattt aacagcaaat ccagttgact
      961 caactggaac gaacttagac ccttctgcag aaggatttag agtaaataaa atcgataaac
     1021 taggtgtagc aggagctaaa aatattgatg atgtccaatt ggccgaaata actataaaaa
     1081 atagtgacct aaatacagtt tcaccacaag atttatatga tggatataga ttaactgtta
     1141 aaggtaatat ggtagcaaat ggtacatcaa agtcaattag tgatatttca gcaaaagatt
     1201 cagaaacagg aaaatataaa tttactatta agtatactga tgcatctgga aaagcaatag
     1261 agcttactgt agagagtaat aatgaaaaag atttaaaaga tgccaaagct gcattagaag
     1321 gtaattcaaa ggttaaattg atagctggag atgatagata tgcaactgca gtggctatag
     1381 caaaacaaac aaaatatact gacaacataa ttatagttaa ttcaaataaa ctagttgatg
     1441 gattagcagc tacaccactt gctcaatcta aaaaagcacc tatattgtta gcatctgata
     1501 atgaaatacc aaaagtaact ttagattata taaaagatat aattaagaaa agcccatcag
     1561 ctaaaatata tatagtgggt ggagaatcag cagtatcaaa tacagctaaa aagcaattag
     1621 aatcagtaac taagaatatt gaaagactag ctggagatga tagacatacg acttctgtag
     1681 cagtagcaaa agctatgggt tcttttaaag atgcatttgt agtaggtgcg aaaggggagg
     1741 ctgatgctat gagtatagct gctaaagctg ctgaacttaa ggctcctata atagtaaatg
     1801 gctggaatga tctttcagca gacgctatca aattgatgga tggaaaagag attggtatag
     1861 ttggtggctc taacaatgta tctagccaaa ttgaaaatca acttgccgat attgataaag
     1921 atagaaaagt tcaaagagtt gaaggagaaa caagacacga tactaatgct aaagttatag
     1981 aaacatatta tggcaaatta gataaactat atatagcaaa agatggatat ggaaataatg
     2041 gtatgctagt agatgcattg gcagcaggac ctctagcagc aggtaaaggt ccaatacttc
     2101 tagctaaaac tgatataaca gactcacaaa agaatgcact tagtaaaaaa ttaaatcttg
     2161 gtgcagaagt aactcaaata ggtaatggag ttgaattgac agtaatacaa aagatagcta
     2221 aaatactagg ttggtaataa cttatactgt ggagaagatt ccttaattaa tacaggaatc
     2281 tttttctata attatgctat ttattgtaaa ttataacatt ttataaagta ggaggatgta
     2341 gtagtggtag atgcaacttt attttttaca ccacatcaag atgatgaaac cttaagtatg
     2401 ggaagtgcta taattgaaca tgttgaaaaa agtgatacac atgtcatact atgcacagat
     2461 ggtagtaaat caatagtaag aaaagttttg gatgatggag ggtcatgttc gtatcatatt
     2521 aaagatgttc ataaatattc tttatcagaa agtgaatttt caaaagatag agatgaagaa
     2581 tttaaggata gctgtgaagc aatgggtgta aaagaaagta atatacatat agaagataat
     2641 agagcacatg atggtgagct aagtaaggaa aaggcaaggg aaataatact taagtactta
     2701 gaagaatatc cagatgcaaa agtaaaaact gttactccat ttaaagctag tggaatacat
     2761 gaagaccata gagcattagg agaagctgca ctagaattgt atagagaagg caaaataaaa
     2821 gatttaagat tttatgtaga accatatgac tataaggatt ttaaaaaagt taatccaaat
     2881 gtagaggtat ggaaggtatt acctagtcaa gaggagaagt tattaagtgc aatgaatgca
     2941 tataagaaat ggaatcctga gagtggacat tatgctatag gatatcattc agtaaaatct
     3001 cattttgatg agctagctat aaataaaata caatatgtac atgctccata aaatattata
     3061 aaagaattag gaggtaagaa ttaatgaaaa tatcaaaaaa gatagtgtct ttgttaacta
     3121 tgacattttt aactgttaca ttatatggaa atacatctaa tgcatctaca aaagatacat
     3181 taacgggttc tggaagatgg gaaacagcaa taaaaataag tcaagctggg tggacaaagt
     3241 ctgaaagtgc tgtcttagta aatgacaatt ccatagcaga tgctttatca gctactccat
     3301 ttgcaaaggc aaaagatgcg ccaatattat taactcaaag taataaattg gatagtagaa
     3361 caaaagcaga attaaaaaga cttggtgtga aaaatgtata tttaataggt ggttcaattg
     3421 cattaaattc agagattgaa aagcagttga atgcagaaaa tataaatttt gaaagaatat
     3481 ccggaaatag tagatatgat acttctttaa aattagctga aaagctagat agggaaaaat
     3541 ctatatctaa aatagtagta gtaaatggag aaaagggact tgctgatgca gtgagtgttg
     3601 gagctatagc tgctcaagaa aacatgccaa taatactttc tgattcagag aatggaactg
     3661 aagtagctga taattttata gatagtaaag atatagcaaa atcgtatgta ataggtggta
     3721 catattctat ttctaattct gtagaaagaa gtttaccaaa tgcaacaaga atagcaggta
     3781 gtagtagaag tgagacaaat gcaaagatta tagaagaatt ttataaagat actcatataa
     3841 aaaatattta tgtaacaaag gatggtacaa agaataagaa tgatttaata gattctttag
     3901 cagtaggtgt attagcagct aaaaatagtt ctccaatact tttagcagga aataagcttg
     3961 atactactca aaagaatgta ttaaatacta aaattataga tagtgttatt caagttggag
     4021 gattaggaaa tgaagagtct gtaaaaaata tagttgatat gcaagaaaaa actaagtata
     4081 ttgtagaaac tgtggatgaa ctttatgtag ctgtaaaaaa agctgatgct aatgatgtta
     4141 tagaatttaa acctaaaaag gaagtaagtg attctattga tatagaaact agtaaagcaa
     4201 tatctattaa ctttgaagga gtatataatc aatcaattac tatagatatg ccaaactctg
     4261 aaataaagaa tattggtaaa ataaaggata ccctacaaat aaaaaatata aaaagtagta
     4321 ctctaataaa tgaaggtact atagatgatt tagatattta tgatgaaaat ggatgtagaa
     4381 tagaaaatga aagttctggt gaaatttcac ttataactat attgaaggat gcaaaaaatg
     4441 tatatataat aaatgaagga aatataacta agatacttaa taattgcaat gatgttgtag
     4501 ttagaaattc aggtaaaatt gatatagtat ctgggagtga acaaccagct ataagtggta
     4561 aaaagccaaa tattaatgac actgaagatg aagaagagtt ggcaagagga ttaaatgtta
     4621 agtcagaagc ttgtagttct ccaagaaaaa attatgtaga tataacgata ttaagcaatc
     4681 taacaagttc taagtatgaa ctttattata gaattgttaa ctataaacct tctgcaagat
     4741 atgtaggaca gcaaataaat acaagtgatt gggagattgt tcctgtatat ggaagtaagt
     4801 ttactaaaag agtaaaaaat ggttcatata tagaagttgt agaagttaaa aattcaacaa
     4861 atgagatatc tagatggggt agatctaata taacagatga tgggttttag ataaattatt
     4921 ttaagcagac aactgttttt ttattgtctg ctatttattt tctaaaaatt atcattttac
     4981 taaacaaata atttaaaact ataacaacta tattagtaaa tatttttaca ataacatcat
     5041 ttacaaaaag caaatcaatc attacataca taattaacat ttcaacgaca ccagaaagta
     5101 gcctaaaact aacaaaagac aaaaattcct tgaataagaa ctttatttca attcttttac
     5161 tcccaaacac aaaaaactta ttagtaacat aagcaaataa aacagcaagt atccatgcca
     5221 aagcatttgc aaccataaaa ttaaataaaa taactctagt aaaaaataaa tacgaaacta
     5281 tatttacaag agtagtaaat gctccaaaaa ataaatataa tattgtctct ctatgttttt
     5341 ttaaaatcaa atataatcct cctaagctaa tttaatataa atatacttaa agatactaac
     5401 aaacattagt atagcacatc tattaat
//
LOCUS       DAEPUT010000155         5401 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.159, whole genome shotgun sequence.
ACCESSION   DAEPUT010000155 DAEPUT010000000
VERSION     DAEPUT010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5401
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.159"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(57..899)
                     /locus_tag="KRL22_003757"
     CDS             complement(57..899)
                     /locus_tag="KRL22_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1274179.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(1160..3202)
                     /locus_tag="KRL22_003758"
     CDS             complement(1160..3202)
                     /locus_tag="KRL22_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBH1274180.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVVKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATVLLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQKGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            complement(3354..4325)
                     /locus_tag="KRL22_003759"
     CDS             complement(3354..4325)
                     /locus_tag="KRL22_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBH1274181.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     QTLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(4326..5303)
                     /locus_tag="KRL22_003760"
     CDS             complement(4326..5303)
                     /locus_tag="KRL22_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1274182.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
BASE COUNT         1761 a          931 c          549 g         2160 t
ORIGIN      
        1 attaaaatta aacataatat attaaatcta tacattctgt attaaactac tctttattat
       61 aaattcagta cagatataac tcttttgata tgtaatgtta aataaagtag ttcatcttga
      121 cttacatagt aatcataatt cttttctaca tgagttttta ttttatatgc acaatcataa
      181 tccttttcat actttacttt aattatatct ataatttcat tatttgtatc attgattttt
      241 tcttttttta ctaatcgttt tgcaaagaat tttaaatgag tcagaagcct atcataattt
      301 atatcatctt ctttaaattc aactctataa taatatctta taatatttag tatgtctttt
      361 acaattttag taattaatag tgattccttt gaacttccct tatagtttga atttactata
      421 tgcattgcta taaaaccagc ttcatctact ggaaatttca catcaaattc tttatttata
      481 taatctacag cccatttccc aatctcatat tcttttttat gtattctttt tatctcatgt
      541 agtaaatcat tctttatagt tatgttttca tgatatcttt taattgcaaa tgcaatatgg
      601 tcagtaagtg ctacataaat atattcataa agcttagtgt tcaaattctc ctctgcataa
      661 gcaattattt cagtactaac ctcaaaaaat ttctcatcaa cctggcttgc tagtttacta
      721 attttatcta aaaagctttc atcttgtatt acaaaagttc tttcaatttt acttttatct
      781 atttcttgac ctttcttttt ttgaaaccca attccacatc ctgttaatat taattctttt
      841 tttatatttt catctaaaac taatacaaca ttattattat aaatttgttg aataatcata
      901 atcaatatct ctcccaaaat acaatttccc ttattcataa aaaaatacct aaattaagat
      961 acaattcacc tgtatacctt aacctaggta ttgcctgctt accagtaaca atccagcttg
     1021 ttaatgctta tatattgtat tcaatttatg gttttattct attataaata aatatatatg
     1081 tcaagtaaat tattgaaaac tatttcctat tttttagtat taattttaac atcaaaaatc
     1141 aaattttatt ccattatatt tatgattcta tcatcatcat ttcatcatag agaatatttt
     1201 ccaataactc tttagccact tctcttgata tttgcttagt ttcaactaat tgttgaacac
     1261 tgtctctttg actttgtatc gccattactc tgtagtattc tactcttgcc tcaaacttat
     1321 catcattttg aatctttcta gtaatccaat tcaaataacg attatagaat ctgattgcta
     1381 ttaaggcctc atgtctgtta tcttcatcag tatttttatt tataaatgat atagcagttt
     1441 tagtagaaag tgcatatgca tggtgaaact ctttgattat ttctttattc tcagatacta
     1501 tttttgtaat tttttctttt acttctttct ttacttttct atttataatc cacatgctta
     1561 tttttaattt tacaatttta aatatagatt tttgaacaga ttttcttgat tttgtaatat
     1621 aaaatctata caatttaaag gctctatcag aaattttacc atcttctaat agtttcaaaa
     1681 cagctaataa tcccttttgg tctgcttctg caatcatcat acttataagt ttattatctg
     1741 gagtatttag tattcctttt tctgagtcta ccaactgttc atttaaatca tgtataactg
     1801 gttgtacttc ttgtgctttt tcattactaa gttttaaaat ggcttctttc aaaattagtt
     1861 tatatgcctc tttatcagat aataaaggtt ctgactcttg tacgttattt tttaataatc
     1921 ttggcagtaa aactgttgcc aatactaaac ttataagaat aacttctgat gatataaata
     1981 aaacagtatc tctcattgga aatacatctt tatcagccaa ataaaaaggt atagataagg
     2041 cagttgctag tgtaaatgta ccatgaacac cacaagtagc aactattagt gagtatttac
     2101 atttagaaat actctctttt acaacttctt catccttaaa acctaaaaaa cctacaaaaa
     2161 aattatttaa aggattcttt ttaggtttta taaaagaatt atgccataaa tatacccata
     2221 taaatcttat aacaaataaa ataagtacaa ttaaagtaga aataaaagtc aattccaatg
     2281 ccatattttc atttttacta ctaagtcctg tatatatact tggtaacaaa aaaccaagca
     2341 gtgtaaagac aaatccattc aatacatact ccaaaacata ccaagtattg tctgatatta
     2401 tccttaattt agtagttgta ttttgtaaat gctctttttc aattccatga gctatccctg
     2461 ccattacaac agctaggatt ccagatactc ctatttcttc tgctacaaaa tatacaaaaa
     2521 gtggagtcat tatttgtata actattacca ttggaatttc ttccaaattc cacttgtgta
     2581 aactaagtct tatttttata attatgtatc ctaaaatact tcctactatt attcctccaa
     2641 aagctgtaat cataaattga atccctgcct cttctattga aaaaactcct gtaactgtgg
     2701 caagtactgc aaccttaaat gctactactc cagcagcatc atttaataaa gattcacctt
     2761 caagtatact catcatattt ttaggaaaat ttaatccttg tgtaattgat tttactgcta
     2821 ctaaatcagt tggagatatt actgctgcca aagcaaatga aacagataat ggcatcccag
     2881 gaataagaaa atgtataaag attccacctg caaacacggt tattaaaact aaaccaaatg
     2941 caagaagcaa aattggtttt ctaagctcta atagctcttt tctcgataca ttttgtcctt
     3001 cactgaatag taatggagct atgatacata ttacaaatat ttctggatta aatgaaaatg
     3061 agaatttaaa tggcaaaata gacaatataa tccctagtac aatttgatat attgcaagag
     3121 gaatattact ccactttttg ctaaatacag ttgaaatcgt tgtacaaacc aataatccca
     3181 acaatgttac taaaattgac ataactacct ctcttttcaa taataatatt atagattaaa
     3241 cttatatatc aactaactta atattaacag catgaaatcc catcttaatc aaaaaaattt
     3301 tcagtttatt ctattattct tattatatac atcaaattta atttttgaaa tatctatact
     3361 agatgacatg caacaaaatg atttcttgat atttctttta aaactggaat ctcttttttg
     3421 catatttcct tacaataagg gcatcttgta tgaaacttac atccacttgg tggatttgtt
     3481 ggagatggta tgtctccttt taatataatt ctatttttct taattgtagg gtcttgtatt
     3541 ggtactgcgc tcataagtgc ttttgtatat ggatgttgag aatgtaagta aagttctcct
     3601 ttagttgcaa tttctattat agaacctaga tacataacac aaactctatg tgcaatatga
     3661 tttactacac tcaaatcatg agatataaat aaatatgaaa gtttatattt atcctgtaaa
     3721 tccataagta aatttataat ttgagattga atagaaacat ctagtgcaga aacaggttca
     3781 tcacaaacta taaattctgg atttaatgct aatgctcttg ctatacctat tctctgtctt
     3841 tgacctccag aaaactcacc tggttttcta tttaaatggt acttagaaag accacaactt
     3901 tctacaacat ttaatatatt atcttttatt tcattctttg gcactaaatt atgttctata
     3961 actgcctcgg atattatttg ttccacattt aatcttggat ttaatgaact atatgggtct
     4021 tgaaatatca tttgcatttt gggtcttaac tttctaagtt cttccttctc taacttatat
     4081 atatctacac cattaaattc aactttacct tcagtttttt caattaatct aagaatggtt
     4141 cttcctgcag ttgattttcc acatcccgat tctccaacta tagccaaagt ttgtcctttt
     4201 tttaaatcaa aagaaattcc atctactgcc tttacacatt taatttcctt atcaaataat
     4261 ccagatttaa cttcaaagta ctttttaaga ccttctactt ttaataaact ctcttctttt
     4321 ttcaattata tctcctcctt tttatataac caacatgcaa tactatgacc actattcaat
     4381 tctattaaag gaggtatctg agttctacat ttatcacata ctttttcaca tctatcacta
     4441 aaataacatg aatctggcat tccaattgga tttggtactt gtcctggaat cgaatacaat
     4501 cttttatctt tgttttttcc aagagcaggc tttgatttta gaagtccaat agtataagga
     4561 tgttttggat ttttaaataa ttcaacaacc tctgccactt ctataatttt accagcatac
     4621 atcactaata ctttgtcaca catttctgca actactccca aatcatgtgt aatcatcatt
     4681 atagatgtgt ttaatttttc ttttatattt ttcattatat ctaaaatctg agcttgaata
     4741 gtaacatcta aagctgttgt tggttcatca gctataagta attttggatt acatgataaa
     4801 gccatagcta tcattattcg ttgtctcata ccacctgata attcatgtgg atatgaatta
     4861 tatatttctt cagctcttgg tatttctacc agttttatca tatcgattac ctttttctta
     4921 gcttcttcct ttgataaatc ttgatgtatc ataatacctt caatgatttg acttccaaca
     4981 gtaaacgctg ggtttaaaga tgtcattggt tcttgaaaaa tcattgatat ctcattccct
     5041 cttattccca taagttcatc ttcattcatc tttaaaatgt ctttgcctcg aaagattatt
     5101 tctccacctt ctatttttga tgttggaagt aacttcatca aagacatggc tgttacagac
     5161 ttaccacatc ctgattctcc aactattcca atagtttcac cttcatttat attaaaactt
     5221 acttcattta cactctttac aatcccttta tctgtatgaa aataaacttt taaatcttta
     5281 acctcaatta gtgctttact cattattttc tcctctcagc aaaattactt aagataacat
     5341 acaccttttg attgtatttt ataaaaattt aaattacaac attttcttac attttattat
     5401 t
//
LOCUS       DAEPUT010000156         5322 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.160, whole genome shotgun sequence.
ACCESSION   DAEPUT010000156 DAEPUT010000000
VERSION     DAEPUT010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5322
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.160"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            107..838
                     /locus_tag="KRL22_003761"
     CDS             107..838
                     /locus_tag="KRL22_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274183.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
     gene            complement(995..1201)
                     /locus_tag="KRL22_003762"
     CDS             complement(995..1201)
                     /locus_tag="KRL22_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274184.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(1604..1999)
                     /locus_tag="KRL22_003763"
     CDS             complement(1604..1999)
                     /locus_tag="KRL22_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH1274185.1"
                     /translation="MKALEFLNKARVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSSKKIDVEL"
     gene            2140..2532
                     /locus_tag="KRL22_003764"
     CDS             2140..2532
                     /locus_tag="KRL22_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274186.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            complement(2632..3048)
                     /locus_tag="KRL22_003765"
     CDS             complement(2632..3048)
                     /locus_tag="KRL22_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH1274187.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(3063..3974)
                     /locus_tag="KRL22_003766"
     CDS             complement(3063..3974)
                     /locus_tag="KRL22_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1274188.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            complement(4156..5178)
                     /gene="splB"
                     /locus_tag="KRL22_003767"
     CDS             complement(4156..5178)
                     /gene="splB"
                     /locus_tag="KRL22_003767"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HBH1274189.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
BASE COUNT         1902 a          812 c          597 g         2011 t
ORIGIN      
        1 aaaaatattc tattataatc tttagaacaa acagtagtaa atgttatctt cataaacaaa
       61 tttatttttc acaagtacaa tacttattta aaaaaggagg tttaatatgt taagtaaaaa
      121 aaatgtaagt ttaattattt tagtaataat tttaagttta ttaactgcta tatttatttt
      181 caataataaa aatactaaca ataaattgaa agaagttact aagaataatg aagaaatagt
      241 acctaaaaac ttagaaggtt taagtataga acaattaata gagattagag ataaagccat
      301 tgataaaaat ttagaaggtc ttagggaatt tggagaagat tcagtaaaaa aacgtaaaga
      361 ttcaatttta aactttgaat ttggattagt agcttttgtt aacaagaatt atagcaactt
      421 aacagaaaaa gagaaattaa taagacaaat taatattgtt aactatgaaa actctataaa
      481 tgatataatg gatccttcag gttcattctt tgaattagca aatcagaatt accaagtgaa
      541 tgagtttcta ttaaaaaacg gaaaagatta taaagaatgg tcatatgaag gtctagattt
      601 tctaattgat catctagaag aactgtgcaa atttgttgat tttgatgtaa aagatgtaat
      661 agatattatt gatcctacaa taaaaacaga cctttcagag gaacaaaaga aatctttgaa
      721 tgataaatta aagaaaatat cttcaagtga tactttaagt gaagaagtta aaaaggagat
      781 aaaaaactgg gaaaacaatt taaataattt aaatatgaat aaaaataatt ctaattaatt
      841 ttctcataag aaaaatgctt atatcgtgat aatgtgaaat gtacataatt ataaacaaaa
      901 aaggggctgt gacactaaaa aatagtgcta cgcccttttt tatttgtaat aatcatcaat
      961 acaaattatt ttattatatg taattattta tgtcttaacc aattttatcg aaaataacag
     1021 tcttctcttt taaagagatt tttcctactt gatatccata ttcatttaat tcctttttat
     1081 atttcaaaaa cgaatggtct atctctatcc cagcaatatc ttttatttct tcaaaagtta
     1141 atttaaacga ttgactattg tttttcttaa catattccca taaagaacta tatttactca
     1201 tcttatatca ctccttttaa aatcatatct tatctattaa tttatattct atcattatta
     1261 atgtataaag tcatgctact tattatttat atataaaaat atccaaataa taagtagcaa
     1321 ttttttatag tcataatatt tttttcagat taaataaaaa tcaattatag ttaaaatatt
     1381 ttttaaaaga aatctatccc attataaagt aaattttaat tatcttattt ctagtatgta
     1441 attattcaaa atagtatatc attattgaaa tacacatcta ataactaaaa atttttacat
     1501 attcattatt taaaaatctt tttattgcat ttaaattaaa tctatcaaca tttcagtaat
     1561 aacgttttct taattttcac tatggatgtc gattcaatta taattaaagc tctacatcaa
     1621 tctttttact actcattgaa caacaactaa cttttgcctt atcaatagag aatatttcaa
     1681 acttaccatc tcctacagag tacatctgac ctaaacttgg cattatttca agtgccttag
     1741 cttgtgtttc ttttgatgta acaaatactg cttcacctaa aatacgtaga gtattaaggt
     1801 tttggtctat acaacaaagt tcaacctttg gattaaaaat aagttgctta aacatatcct
     1861 tttgattaga tgtgcaaaat gtaagtttac cattgtattc cataacaaat cctaaaggac
     1921 gcacatgtgc ttgattgttc tcatcaactg ttgctaaata ataaactcgt gccttgttca
     1981 aaaattctaa tgctttcata attcttacac cccttttaaa tacttgtatt aaggattatc
     2041 ctttgatata attttaatat aaaatacaga aaaaacaagt atgcagtttt ttctgataaa
     2101 gtataaaaaa gatactacta taactaagga gtaattaaaa tgagtataaa tactgaaaaa
     2161 aatataacta aaaacgttga agaattaacc tgtccaatcc gttatgcatt agacattgtc
     2221 ggtggtaagt ggaaattacc tattatatgt atgttagcag ttgaaaatcc aattagatat
     2281 agtagcataa aaagaaaatt ggatggcatt acaaatacta tgctagctca atcattaaaa
     2341 gatttagagt ctactggtat tgttcatcgt aaacaatata atgaaattcc tccaaaagtt
     2401 gaatatacat taacaagtaa aggtaaaagt attgtgccta ttttacaaca atttgctaat
     2461 tggggtgcta ctaatatgca agaaaaaaac acatgtggac ttagttgcaa agaatgtaga
     2521 aagataaagt aaatttaaat ttactaaatt attcatatta tagactatat attaatttat
     2581 ctgattgaat ataaaaacag gatgacttat atattcatcc tgttctatat gttaagctct
     2641 aaatttaatt agttcaagca tatcgtttaa taccaataaa ctatctactt gaatcattag
     2701 ccatttactt ccattaaaaa agtttacctc attatatatt tttttgatat aatcacaaca
     2761 agtattaata aataaatcaa cctctactct attgctttca cttacaataa ccaaagcttt
     2821 aaaataacct tcttgtggat ataaagtaca tagtgattta cctctttttt tatattttac
     2881 attccaacct ctttgcattg aacatttact gtattcaagc ttaggttcta cattataagt
     2941 agaaaccaaa gttttattta acttgtccca taatggatta ttaataaatt cattaatttg
     3001 ctcaaatgta ggtttagtat cttgaaaaaa cgcatcttgc caattcatat tcatcatcct
     3061 ttctattgtt caataggaac cggaacaatc caatgttcca gatatgctgc ttcaggtgta
     3121 gtggggtaat acatctcaat tgcaaaatca gtagttgtta aattatgttt cttcatccat
     3181 ctttccataa atttatctgc tttaaaaaca gctgaattaa ctaactcatt aaagttttct
     3241 gcctcaaatc cacatactaa atattcttta gctggcaact caaaagtact atatccttct
     3301 actgatgtac ctgactctac ctctacacct gccatataca tacaatttcc ttcttttgca
     3361 tttcccatat aaagagcagc aaattcattt ccacctggaa tttgatttgg tatattatgt
     3421 ctttgacttc caagtttcat ccataattcc tctactattg caattccagt tgtttcaccg
     3481 cccaccaact ggcaaatagg tacttctatt tctattccaa caaatgtcct tggattactc
     3541 aatgtcttac gattgacttc aatcactata tcatctgcaa tcagtggaac accttcatca
     3601 accatagcat aatttaaaat taattctggc ttaataaagt gattgagttt tactggattt
     3661 gctctatatt tttctggagt taatccatat gcttttttaa aggaacgtgt aaatgtctca
     3721 tgactagcaa atccaaaatt taaagctaca tcaagtatac gattcttatg ttctgctaag
     3781 tattcagaag ctcttgcaag acgacgaagc tttatatact ccattacagt cttatttacc
     3841 aatcttttaa atagtctttg atagtaaaat ggtgataaat ttgctttatt tgctaattca
     3901 ttaattgata tttcttctga taaatttgct tctattaaat ccaatgtaat ttgaatagac
     3961 tcccatgcat gcatactata actcctcctg atatttttgt tactcttatc ctttatagta
     4021 tcaaaactag aaaaaatgtt cttgatagat agtgcccttt ttaattttct tatatgatag
     4081 tgctaaatct cattgcttta ttataaacat aaaatgtata aaaataaaat atagcaaatc
     4141 tttaggtaag atttgctata ttatatattt tattaaacta tttttaaata ctccatttat
     4201 ttccttaaga aagaactctt tcatatcatc taattgttct ttatcataca cgtacttacc
     4261 atatccaaat tgaccgtatt taaactttct atcctcattt tccattggca atagtgtatc
     4321 tggataaatc tctagtattc tattttttgc tttagttgta tatctatgag atataacttc
     4381 aaatataatt tttttatcaa aatcctttgg taaagcttct tttatactta taatcagatt
     4441 tttatactct tctttccaac cttcatataa aaacacaggt gctattatga aaccaatctg
     4501 ataaccagcc ctagcaagtt ttacagctga ctctattctt ttatttgcag aggctgtata
     4561 atgctcatgt tcatttataa ttctaggagt attgatacta aatcgtattt ctgtatgatt
     4621 attatgttca gcatccaata agctatccac atcactgtat ttagtaacaa atctaaatct
     4681 tcctttttcc tctcttccaa aaaactctat tgttttcttt aaagaattag tatatggctc
     4741 tactggaact gggtctgatg tagctgcccc ttcaaatatg gttacctgtg gctttctatc
     4801 ttcaatatat ttttttgtct gttcaagtat ttcatctaca tttacaaaca cccttataaa
     4861 tggtttatca cctaattgtg tgttcaaata acaatactca catcttccca tacatccact
     4921 gacaagtggt agttgataat tagcagaagg tttacatgtt tgaaacttca gactttttct
     4981 aatcccaact accatagtct gcttcccact tctatattgt tcatatagat tttcacctgg
     5041 aatatgttct ttaatcctat ttgatgatat attaattatc tctacatctt tattatctct
     5101 aaatttattg tatatttttt tacccacatc agtgtctaaa gttccttttt cgaatattat
     5161 tcttttggga ttaaacattt atttcacctc tacttaaagt ttttaaatcg aagaatttta
     5221 taaaatatta cttaattaat cttccctttt ttaaactcct ttatttatta gaaagtaaaa
     5281 taaaagctta agacaaattt attatatata taacttctat ac
//
LOCUS       DAEPUT010000157         5176 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.161, whole genome shotgun sequence.
ACCESSION   DAEPUT010000157 DAEPUT010000000
VERSION     DAEPUT010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5176
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.161"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            39..1811
                     /locus_tag="KRL22_003768"
     CDS             39..1811
                     /locus_tag="KRL22_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1274190.1"
                     /translation="MENGKFQFFKGVRNCFNMIYLHDKRYLFISMFMAIFQGIVPSIS
                     LLVSQNIINNMQTFSKSVKEILVLLIMYLIINIIPSIFQSFYGYYRIKFNKNFEKHIE
                     TMMLEKSLTLSLKDFEDDNTYDMINRAQSQKGFNITILSENLISIIRESVSTLSLIVV
                     LSQFQLWLIIVVIVIPVLKSLYSIKLGKEQYDVSVNRTWKERKAWYIDYLLSKGYAYK
                     EIMVFRIGSKLINHYKKLKEDIISQDMNIAKKNFIATLLCTVLDSIVSAGIIGFIIIQ
                     GILKKILIGDATTYIQAVQSIKDNVESIFSLFSSVIQDLFYTDLLFKFLDYNCKEDSI
                     EHIKIFEKIGDINKIELINISYKYNHSSEYSLKNINLTLNKNDPIAILGKNGSGKTTL
                     LKILLGFYDDYEGDILINGKNLKDIEKDEYIRKVSCMFQDYIKYEATLKENVAMGDVY
                     KSNLEEKVKSKLKETKLKPSIYEEDGLETILGTWFGKKQLSMGEWQKVAISRTLMKDA
                     DMYIFDEPDSSLDSEAGNELLSLYKKTFENKIGIFITHHIQHAKKITNNIVVLENGKL
                     LESGRHDELMDKKGVYFNLFCNCK"
     gene            1833..3254
                     /gene="ccpM"
                     /locus_tag="KRL22_003769"
     CDS             1833..3254
                     /gene="ccpM"
                     /locus_tag="KRL22_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="HBH1274191.1"
                     /translation="MNQKPFIHTFKAGKSYFIYDVNTDKILKVNAAVYNYLNKIEHNL
                     EKESDWNIEIEDEINTLINYGFLKNKRVSKTMHPETKYIKYHIENNLSSIILQVTQNC
                     NLRCDYCIYSGSYSNRVHTNKRMNIDVAKRSIDYLIKNSSQLNEVSVGFYGGEPLLEF
                     DLIKQIVEYVKVVGEGKEIYFNLTTNATLFNEEIIEFFVKNNITTMISLDGGKEIHDK
                     SRKFANTGEGSHDVVLKNVRYIKNKYPEYYKKNITFNTVINSENDYISIDDFISKNET
                     LKDSNFLASTLNNNYSDKEIVSSDEYILGKSYDRFLTLLNKLKFIKDESMSPLSRIER
                     ALLDDFRYEKNIEGRLELPDVWHHGGPCIPGAFRIFVTTDGEFFPCERVSESSKMGMI
                     GNLDSGVDIEKAEKLLNIGKLYEEQCSDCWAYSYCDICIAKIDDTKCNENEIKPHDCD
                     RIRHSTENNMKDYCVLKSLGYQY"
     gene            3283..4353
                     /locus_tag="KRL22_003770"
     CDS             3283..4353
                     /locus_tag="KRL22_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="HBH1274192.1"
                     /translation="MEKVLIYPFNYNFFTILNHCNKISDIEINSLVSPSGWGLCNKEY
                     NVNNIITKVTNDFQSELKKNSLVWFVDSKENLDLEKFIIPKLKVALKEGKKILYTRDD
                     LNKISRYISHYEFKKINEWNLEKYEIRDIEGISQINTPIIFICGLYGGLDTFDVNIRI
                     GEELRKRGFSILQFGPKKESYLFKMIPIPEFMFDDSISSKTKIINFNHFIKDKEVEAK
                     PDLIIIEVPGELFPFSRKMVGNFGIRAFEISNAVINDCGILCIPSSIYDREYCEELKY
                     FIKGRHGINIDYFSIEKKVIDTYETEVKQKFSYMSLDENFFVEDIEDYEKTFFIHDNK
                     QLLELVDNIVNQLKEYAKVISI"
     gene            4369..4620
                     /locus_tag="KRL22_003771"
     CDS             4369..4620
                     /locus_tag="KRL22_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="HBH1274193.1"
                     /translation="MNYTEKELLLENIFFDVTGINFNKNNNLKKELFFSPSLHIQPRE
                     LLLVFCEVIENFNIKIPEEKLLNRQFTSFDNVLKIINMV"
     gene            4671..4874
                     /locus_tag="KRL22_003772"
     CDS             4671..4874
                     /locus_tag="KRL22_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274194.1"
                     /translation="MSFGKRIEMNNIGVETRGVCTIMCPYTCKMMASSSCNCKNNDYN
                     ARGGSYNTYYNKLIHGQRTPDGM"
BASE COUNT         2105 a          455 c          831 g         1785 t
ORIGIN      
        1 atattttatt tcaattttat taagtatgga ggtgtattgt ggaaaatggt aaatttcaat
       61 tttttaaagg tgtaagaaat tgttttaata tgatttatct acatgataaa agatatttat
      121 ttatctctat gtttatggca atttttcagg ggattgttcc atctatttct ttgttagtaa
      181 gtcaaaatat cattaataat atgcaaacat tttcgaaaag tgtaaaagaa atattagttt
      241 tgttaattat gtatttaatc ataaatataa ttccttcaat ttttcaaagt ttttatggat
      301 attatagaat aaagtttaat aaaaattttg aaaaacatat tgaaacaatg atgttagaga
      361 aatctttaac tttgagttta aaagattttg aggatgataa tacttatgac atgataaata
      421 gagctcaatc tcaaaaagga tttaatatta ctatactatc tgaaaacctt atttcaataa
      481 taagagaatc agtatctaca ctttctctta ttgttgtatt atcacaattt caactttggc
      541 taataatagt tgttattgtt attcctgtat tgaaatcatt atattccatt aaattaggaa
      601 aggaacaata tgatgttagt gtaaacagaa cttggaaaga aagaaaggcc tggtacatag
      661 attatttgtt gtcaaaaggt tatgcttaca aagagattat ggtatttaga attggttcta
      721 aacttattaa tcattataaa aaattaaaag aggatattat atctcaagat atgaatatag
      781 ctaaaaagaa ttttattgct acgctattat gtacagtttt agattcaatt gtatctgcag
      841 gaattatagg atttataata attcaaggta ttttaaagaa gattttaata ggagatgcga
      901 ctacatatat acaagcagtt caatctataa aggataatgt tgaatcaata ttttcgttat
      961 ttagttcagt aatacaagat cttttttata cagatttact gtttaaattt ctagattata
     1021 actgtaaaga agactcaatt gaacatataa aaatatttga aaaaataggg gatataaata
     1081 aaatagagtt aataaatatt tcatataaat acaatcattc atcagagtat tctttaaaaa
     1141 atattaattt aactttaaat aaaaatgatc ccattgctat actaggaaaa aatggttcag
     1201 gtaaaacgac acttttaaaa atattattag gtttttatga tgattatgaa ggtgacatct
     1261 tgataaatgg aaaaaattta aaggatattg aaaaagatga atacattaga aaagtaagtt
     1321 gtatgtttca agattatatt aaatatgagg ctacattaaa agaaaatgtc gccatgggag
     1381 atgtatataa gagtaacttg gaagaaaaag ttaaaagtaa acttaaagaa actaaattga
     1441 aaccaagtat ttatgaggaa gatggattag aaactatttt aggaacctgg tttggtaaga
     1501 agcaactttc tatgggtgaa tggcaaaaag tagcaatatc tagaactctt atgaaagatg
     1561 ctgatatgta catttttgat gaaccagatt catctttaga ttctgaagcg ggaaatgaac
     1621 tcctttcttt atataaaaaa acatttgaaa ataagattgg aatatttata acgcaccata
     1681 tccaacatgc aaaaaagata actaacaata ttgtagttct tgaaaatgga aagttgttag
     1741 aaagtggaag acatgatgaa cttatggaca aaaagggtgt ttattttaat ttattttgta
     1801 actgcaaata aatattaaag ggaggttaat taatgaatca aaaaccattt atacacacat
     1861 ttaaagctgg aaaatcatat tttatttatg atgttaatac ggataagatt ttaaaggtaa
     1921 atgctgctgt ttataattat ctaaataaaa ttgagcataa tttagaaaaa gaaagtgact
     1981 ggaacataga aatagaagac gaaattaata ccttgattaa ttatggattt ctaaaaaata
     2041 aaagggtaag taaaacaatg caccctgaaa ctaagtatat aaaatatcat atagaaaata
     2101 atctatcctc tattatttta caagtaaccc aaaattgtaa tttacgttgt gactattgca
     2161 tttattctgg ttcatacagc aacagagttc atacaaataa aagaatgaat atagatgtag
     2221 caaaaagaag tattgactat ttgattaaga attctagtca attaaatgaa gttagtgttg
     2281 gcttttatgg aggagaaccc ttacttgagt ttgatttgat taagcagata gtagaatatg
     2341 taaaagtagt tggagaagga aaggaaatat actttaatct aactacaaat gcaactttat
     2401 ttaatgagga aataatagaa ttctttgtaa aaaataatat aacaactatg attagtttag
     2461 atggaggaaa agaaattcat gataaaagta gaaaatttgc aaatacagga gaaggatctc
     2521 atgatgttgt attaaaaaat gtacgttaca taaaaaataa atatccagaa tattataaaa
     2581 agaatattac atttaataca gtgataaatt cagaaaatga ttacatttct atagatgatt
     2641 ttatatctaa aaatgagact ttaaaagatt caaacttttt agcttccact cttaataata
     2701 actattctga taaagaaata gtttcatcag atgaatatat attaggtaag agttatgata
     2761 gattcttgac tttactcaac aaattaaaat ttataaaaga tgagagtatg tcacctttat
     2821 caagaataga aagagcctta ttagatgatt ttagatatga gaaaaatatt gaaggtagat
     2881 tagagttacc agatgtgtgg catcatggtg gaccatgtat accaggagct tttagaatat
     2941 ttgtaactac agatggagaa ttttttccat gtgagagagt aagtgaaagt tctaaaatgg
     3001 gtatgattgg aaatttagat agtggagtag atatagaaaa ggctgaaaaa cttttaaata
     3061 taggaaaatt atatgaagag caatgttctg attgttgggc ctatagttat tgtgatatat
     3121 gtatagctaa gattgatgat actaaatgta atgaaaatga aataaaacca catgattgtg
     3181 acagaattag acattctaca gaaaataata tgaaagatta ctgcgttttg aaatctctag
     3241 gatatcaata ttaaattttc taatgaaagg aaagatggga ttatggaaaa agtacttata
     3301 tatccattta attataattt ttttactatt ttaaatcatt gcaataaaat ttcagatata
     3361 gaaattaatt cactggttag tccttctggc tgggggttat gcaataagga gtataatgtt
     3421 aataatatta ttactaaagt tacaaatgat tttcaaagtg aacttaaaaa gaattctttg
     3481 gtatggtttg ttgattcaaa agaaaatcta gacttagaaa aatttataat tcctaaatta
     3541 aaagtagctc taaaagaagg taaaaagata ttatatacac gtgatgatct taataaaata
     3601 tctaggtata tatctcatta tgaattcaaa aagattaatg aatggaattt agaaaaatat
     3661 gaaataagag atatagaggg tatatcacag ataaacacac caataatatt tatttgtggt
     3721 ctttatggag ggttagatac ttttgatgta aatataagga taggagaaga actaagaaaa
     3781 agggggtttt caatattaca atttggccct aaaaaagaga gctatttatt taaaatgatt
     3841 cctataccag agtttatgtt tgatgattcg ataagtagta agacaaagat tattaatttt
     3901 aaccatttta taaaagataa agaggtagag gcaaagccag atttaataat tatagaagtt
     3961 ccaggagaat tattcccttt ctctagaaaa atggttggta attttggaat tagagctttt
     4021 gaaatttcta atgcagtaat aaatgattgt ggtatattat gtattccatc aagtatatat
     4081 gatagagaat attgtgaaga acttaaatat tttattaaag gaagacatgg tataaatata
     4141 gactatttta gtatagagaa aaaagttata gatacatatg agacagaggt gaagcaaaaa
     4201 ttttcatata tgtcattaga tgaaaacttt tttgttgaag atatagaaga ttatgaaaaa
     4261 acatttttta tacatgataa taaacaatta ctagaattag tggacaatat agtgaatcaa
     4321 ttaaaagagt atgctaaagt aatatctatt tagaattgga ggttaattat gaattacact
     4381 gaaaaggaat tactactaga gaatatattt tttgatgtga ctggaattaa ttttaataaa
     4441 aataacaatt taaaaaaaga attatttttt tcaccgtctt tacatataca gccaagagaa
     4501 ttacttttag tattttgcga ggtaatagaa aactttaata taaaaattcc agaggaaaaa
     4561 cttttgaata ggcaatttac gagttttgat aatgttctaa aaataatcaa tatggtatag
     4621 gttaataaag gtataaagta agtgatctta tagaaaaggg gaggatatga atgagttttg
     4681 gaaaaagaat agaaatgaat aatataggtg ttgagacaag aggtgtttgt actattatgt
     4741 gtccttatac ttgtaagatg atggcatctt catcttgtaa ctgcaagaat aatgattata
     4801 atgcaagagg aggatcatat aatacatatt ataataaatt gatacatggc caaagaactc
     4861 ctgatggaat gtaaatattt cagtaataag tatactatta aattgattta gcatatttga
     4921 ttaaatttat ctttcttact ttatttcctt ttattataaa aatatgcagt tgattataat
     4981 taagagtgtg attttataat aactgcataa atagtatctg ttatataaat cacctcttca
     5041 attattatag tggtaaatat agtgattagg ggtgattttt acaatttaaa agtataaatt
     5101 aattaaaagt tattataata aattatactt atttaaatag taagaattaa aagtaaagtt
     5161 tttaaatata tttgta
//
LOCUS       DAEPUT010000158         5066 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.162, whole genome shotgun sequence.
ACCESSION   DAEPUT010000158 DAEPUT010000000
VERSION     DAEPUT010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5066
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.162"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            38..1921
                     /locus_tag="KRL22_003773"
     CDS             38..1921
                     /locus_tag="KRL22_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBH1274195.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            2146..2826
                     /gene="pgmB"
                     /locus_tag="KRL22_003774"
     CDS             2146..2826
                     /gene="pgmB"
                     /locus_tag="KRL22_003774"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH1274196.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            2823..>5066
                     /locus_tag="KRL22_003775"
     CDS             2823..>5066
                     /locus_tag="KRL22_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_097546124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH1274197.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFHRELDMKNGILNRRFIVNINDKKFEVRVARFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGK
                     PIKIIVYG"
BASE COUNT         2091 a          457 c          961 g         1557 t
ORIGIN      
        1 gattatataa attattataa aggagggaaa ttttaaaatg tctaataaaa ataaagaaaa
       61 tataacttta agtaatcaaa tcaaaggaac aattcaaaat agtttaacaa aagaagctat
      121 attacatata ccaatgagca attatgccta tggttatgat agagaaacac tacatataag
      181 acttagaact aaaaaaaatg aagcgaaaag agtaatttta cgaataggag accaatatgt
      241 gtgggataaa ggcggtgcag gaggaggaaa tttaaatgca tctggagttg gttggtctgg
      301 tggaacaaat atagtaatga gtaaagaagt agaaactgaa ttatttgact attggatagc
      361 taagtgtaag cctttaaata aacgctcacg atatggcttt ataatagaag gtcaagagga
      421 aaaactttta tttacagaaa aaagaataat agagttggga aatgaaaatg atgaaaagga
      481 attatgtgaa ataggtaatt tttttggata tccatattta aattatatag atatacctaa
      541 agtgccaaat tgggtgaaag atactgtttg gtatcagata tttccagata gatttgcaaa
      601 tggtgacccg tctataaacc cagaaggagt agataaatgg ggagctattc caaccagaga
      661 taattttaca ggtggagatt tacaaggtgt gatagaacac ttagattatt tgagtgattt
      721 gggaataaac ggaatttact tttgccctat tacaattgga aaaaccaatc atagatatga
      781 tacggtagat tatatggagg tagaccctac attaggagat aaagagactt taaaaaaact
      841 aatagaagaa gcgcataaga gaaatataaa aataatgttg gatgctgttt ttaatcatat
      901 aggatattat tctaaacagt ggcaagatgt agttcaaaat aaggaaaatt ctcgatataa
      961 aaactggttt tatataaaag atatgagtaa aattgatact ccaatagaac aaatagatga
     1021 aaaaaatata ccttatgaaa cctttgggtg tgaaaaatat atgcctaaac ttaatacaga
     1081 aaattcagaa gtaataaaat atttattgga tgtaggcaag tactggatac aggaatttga
     1141 tatagatgcg tggagattag atgtttcaaa tgaagtagac catgtttttt ggagaaagtt
     1201 tagagaagaa gtcaaaaaag taaaaccaga catttatata ttgggagaaa tttggcatgg
     1261 tagtttacca tggctaatgg gtgaccaatt tgattcagtt atgaattact tgatgtcaga
     1321 agccatgaaa aaattctttt gtacagatga gataaacgcc gaagaattta agtatatgat
     1381 aaatgatgta atggtaagtt atccaataca agttagtgaa gttattttta atttacttgg
     1441 aagtcacgat actacaagaa tattgactta tgctaatgga aatattgata gatttaaact
     1501 tgcatatatg tttatgtttg tacaaacagg atgtccttgt atatactatg gtgatgaaat
     1561 cggaatggaa ggagaattaa gttcaatatc tgaaggtcaa agaaaatgta tggaatggaa
     1621 tgaagaaaaa tggaataagg atatatttga ttttatgaag aagattatta gacttcgtaa
     1681 agaaaataaa gaacttaggt ctatatcaaa tgaatgggtg ttagcagata aggaaaatgg
     1741 aacgattata ttgaaaaaag aatctatttc tataataata aataattcat ctaaaaatat
     1801 aattttgacg ttaccagatt atttagcaaa taaaaaagta aaagatttat atgaagaaga
     1861 aatagttgat ttaaaagaag aactaatgtt agagaaatac aagttcatta ttttaaaata
     1921 atacaaaaaa gtatttattt tagatttcat gttaaattat tatacagttt aaataagtct
     1981 ttataaacga taaaaaaata tggtctacaa gtgagtgaat tgaaagtaga ttttaaatta
     2041 aagactgagt tagagtagat aattttataa ataatatctt aaatacaaga tagaaaataa
     2101 attgattatt agtctaaaaa tttcttgtag aaagaggaaa taagaatgat tgaagcattt
     2161 atatttgatt tagatggtgt aattacagat actgcatatt atcactatat ggcttggaga
     2221 aaactagccc ataaagttgg gatagatata gacacaaaat ttaatgaatc tttaaaaggc
     2281 ataagtagaa tggagtcatt ggacaggata ttagaatttg gaaataagaa atattcattt
     2341 tcagaagaag aaaaagtgag aatggctgaa gaaaaaaata attactatgt atcattgata
     2401 gatgagataa cttcaaatga tattttgcca ggtatagaaa gcttgttaat tgatgtaaaa
     2461 tctaataata taaagatagg tctatcttct gcaagtaaga atgcaataaa tgtattaaat
     2521 catttgggta taagtgacaa atttgatttt atagctgatg caggaaaatg taaaaacaat
     2581 aaaccacatc cagagatatt tcttatgtca gcgaaagggc ttaatgtaaa tccacaaaat
     2641 tgtataggga tagaggatgc aagtgcaggt atagacgcta taaactcagc taatatgttt
     2701 tctgttggtg ttggaaatta tgaaaactta aaaaaagcaa atttagttgt agattcaaca
     2761 aatcaattaa agtttgaata tatacaagaa aagtataatg agtatatagt taggagaatt
     2821 atatgaaatg tttatttagt aatgtagatg agtggaagat tatacaagat aagattgaaa
     2881 tcaaagaaaa tagattagca gagtccataa tgagtatagg caatggatat atgggtatga
     2941 gaggaaacta tgaggaaaat tatagtggag atacacacaa ggggtcttat atagctggag
     3001 tatggtttcc agataaaact cgtgttggtt ggtggaaaaa tgggtatcca gaatactttg
     3061 gtaaaattcc taattcagtc aactatatag gtgtaagaat tttcatagat gatgtagaat
     3121 tagatttagc aaaatgtaaa gtagaagatt ttcatagaga attagatatg aaaaatggta
     3181 ttttaaatcg taggtttatt gtaaatataa atgataaaaa atttgaagtt agggttgcta
     3241 ggtttttaag tatatctgtt aaggaacttg cagtaattaa atacagtata aaatcattaa
     3301 attctaatac taaaataaaa tttgtaccat atttagattc aaatataaaa aatgaagatt
     3361 caaactatga ggaaaagttt tggaatggaa tttcttcaag ttctttagaa tataaaggta
     3421 gtattctttc tcgaacaaag gagaatgcat ttaatacacc agtattcact gtgggttcaa
     3481 tgatgtatat taagacaaat ggtgatgtag aagctgtatc tcatgagagt gattataatt
     3541 actgtgaaaa ttcgataaca atggatgttt taaaaaatga ggttgcaagt atagaaaaat
     3601 atgtatctat aacttcaact agagattata aggaaagtga gctattaaga aaatgtgaag
     3661 acattttaaa tagagaacta tctaaaagtt atgatgatat attaaatgaa catacaaagt
     3721 tatggaataa aagatgggaa agtgcagatg taaaaataaa tggagataaa agtagccaac
     3781 aaggtataag atataattta ttccaactat tttcaacata ttatggagaa gattcgcgat
     3841 taaatatagg tccaaaagga tttactggtg aaaagtatgg aggagctact tattgggata
     3901 cagaagcatt ttgtgttcca gtatatctag gtgtagcaga taaggaggta actagaaatc
     3961 ttttagaata taggtacaat cagttagaac aggcaaagga taatgcaaaa aaactagggc
     4021 ttaaaggtgc tttatatcca atggtaacat ttgatggagt agaatgtcat aatgaatggg
     4081 agataacatt tgaggaaatc caccgaaatg gaagtatagt atatgcaata tataactata
     4141 caaattatac aggtgactat aaatatataa aagaaaaagg aatagatgta ataatagaaa
     4201 tagctagatt ttgggcaagt agagttcatt tgtctacaaa aaaagatttg tatatgatac
     4261 atggagtaac aggtccaaac gagtatgaaa acaatatcaa taataattgg tatactaatt
     4321 atatagctaa atggtgttta gattatgctg tagaaaatat cttacgatta gagaaagagt
     4381 gtaatgaatg tattgacaga aataatgtga ctagggaaga agttgagttt tggaaaataa
     4441 tatcaaataa aatgtatctg ccgtatgatg aggaactaca aataataatt caaaatgata
     4501 attttttaga taaagaattt gtagaagtaa aggatttacc aaaagaaaat tttcctctta
     4561 atcaaaattg gtcttgggat aagattctta ggtcgtgttt tataaaacaa gcagatgtat
     4621 tacagggaat ttactatttt ggaaatagat ttactaaaga agaaaaaaag agaaattttg
     4681 acttctatga aaaatatact gtacatgaat cttctttatc ttctagtatt tattctatta
     4741 ttgcctcaga aatagataac ctagaaaagg cttatgaatt atattcaaga acagctaggc
     4801 ttgatttaga taattacaat aatgatacaa atgatggact gcacataact tcaatgtctg
     4861 gttcatggct ttccattgta catggatttg caggcatgag aacatggaat gaaactctat
     4921 cttttgaccc taagttgcca aaagagtgga aaaattattc tttcaatata aattatagag
     4981 ataatattat taatgtagat gtatgtagtg atttaattaa aatagaaaat ttaaaaggta
     5041 aaccaataaa aattattgta tatggg
//
LOCUS       DAEPUT010000159         5063 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.163, whole genome shotgun sequence.
ACCESSION   DAEPUT010000159 DAEPUT010000000
VERSION     DAEPUT010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5063
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.163"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            66..677
                     /locus_tag="KRL22_003776"
     CDS             66..677
                     /locus_tag="KRL22_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBH1274198.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            975..1313
                     /locus_tag="KRL22_003777"
     CDS             975..1313
                     /locus_tag="KRL22_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBH1274199.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(1719..3155)
                     /gene="miaB"
                     /locus_tag="KRL22_003778"
     CDS             complement(1719..3155)
                     /gene="miaB"
                     /locus_tag="KRL22_003778"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBH1274200.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
     gene            complement(3403..4839)
                     /locus_tag="KRL22_003779"
     CDS             complement(3403..4839)
                     /locus_tag="KRL22_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HBH1274201.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEDQYLILNDCYLIENE"
BASE COUNT         1719 a          761 c          547 g         2036 t
ORIGIN      
        1 taattatata ttattgttaa aactcaatta tataattttt aataatatta ttttaggagg
       61 taaaaatgat aaacgatatt aaaaataaat tcaaaaatta caaaccatat ataaatggat
      121 acaagaatat gaagagagca tctgttttaa ttccaatagt agaaataaat aacacacact
      181 atatattatt tgaagttcgc tcaaaaaatt tgaagcatca acctagcgaa atttcttttc
      241 caggtggtaa aatagaatca ggtgagactc catatgaagc tgttattaga gaaacttgtg
      301 aggaacttgg aacttttagt gacaatatag aagtaatatc aagtcttgac ctccttataa
      361 caccagtaaa gtttatcata catccatact taggatatat aaaaaatatt aataatttaa
      421 atataaacaa ggatgaagtt gaccatactt ttttagttcc tataaaatat cttttagaga
      481 atcctccaaa tacttatagt aatactgtaa aagtttttcc agatgaaaat ctaccatatg
      541 gttcaattcc aaaccaaaaa gattataaat ttgaaagtgg aagttatcct attctgtttt
      601 ataaatataa agattatgtg atttggggaa tgacagcaaa aatactagaa aactttttaa
      661 attttttatc agaataacac tcataataaa ttatcaaaac ttttacataa gaaatttata
      721 aaagtttcta aatttaacaa ttctaaaata tcaataacta tattttgtag cactttttta
      781 ttttattatt gtttgaatat ttgatggttt tcaatgcaat ttcaacataa atactatgta
      841 ttagtgtata ctgttgatga attaaagtat gataatctat ttaataaagt atgaagtaaa
      901 tgattttaat gtgcctttat ggtaaaatta ctaataagta ataaaattaa ttaaaatata
      961 tggaggtgct tataatgttt gctgtaggat ttgttgttat aattgcactt gcctttttca
     1021 ttttaagtgt actattattt aatggaaaag ccagtatgct actagcaggt tataactcta
     1081 tgagtaagaa agaaaaagca cgatacgata aaaaaaaatt atgtagaagt tctagcattg
     1141 ttacttttat tgtctctata atgctattta ttatggcgtt tttgggatat agaatagaga
     1201 gtggtcaaat ggacgaaaaa aaaatggttc ccttttctat aatatttata atagtcatac
     1261 tttccagtgt attttttaat atcctctact ctaacaaaaa atgtaaaaaa taaatagttg
     1321 taagttgagc agttaattat aaaagattga ctgctttttc atgtatattg actactctta
     1381 ttaaatattt taacatttaa aatctatgta aaaataatga atatagtaca aacttctaat
     1441 aatgatttta cctttgtggt tacagtccac tatatataat ttaatatgat aacagggaat
     1501 tactaatgac aactaggtaa gcttttataa aatataataa aacaaaaata gatgtacaat
     1561 gaaattatat cttatatcaa atttattttt attaatagca aaaacttaca ttagcataac
     1621 atatgacaaa ttcgcttaaa ataaaaattt taaatataat ttgttctata gtacatctat
     1681 tttgattagt ttacataatt ttattatttt gtacaatatt aattatttac taatatccca
     1741 tttaatgaaa aagttctagg ttcagtaatt ttgaccataa ctagcttacc aattaaatca
     1801 tcatttccac cttcgaaatt tacgagttta ttttgtctag ttctaccagc aaacttattt
     1861 tcattatttt tacttcttcc ttcaactaga acttcaacta ttctatcttt atatccatca
     1921 tttatttctg cagaaatcct atttacagct tctaacaccc tattaaatct atcatgcttt
     1981 atatcttctg gtatttgatt ttccatttta gcagcaggag ttccctgtct tttagaataa
     2041 ataaatgtaa aagctgaatc atatctaact ttttcaacca catctaaagt gtccaataaa
     2101 tcttcttctg tttctcctgg gaaaccaatc attaagtctg tagaaaaagc aatacctgga
     2161 acttcctttt tagctttttc tattatttct aaataatatt cctttgtata atgtctattc
     2221 atttttttca aaaggctact gcttccacat tgtattggta gatgtaaaaa ctcgcacacc
     2281 ttatcacaat ctctaattgc gtatattact tcatcagata tatcttttgg atgagatgtc
     2341 ataaatcgaa ccctttcaat tccttctata tcattcactt ttcttaaaag ttctgagaat
     2401 gaaactggat tttcaagtgt cttaccataa gaatctacat tttgtccaag taaagtgatt
     2461 tctttcgttc catttgcaac aagctctttt atctcgttaa ttatatcttc aggagttcta
     2521 cttctttctc ttcctcttgt gtatgggact atacaatatg tgcagaaatt attgcatcca
     2581 tacattatat ttacaaatgc ttttaattca aattttctat tacttctaag accttctatt
     2641 acttctccat ccacatccca tacatccact aacattttgt cagaatttat tgattctgta
     2701 agtaattgcg gaaatttata tagattatgt gttccaaata taaggtctac atgtttatat
     2761 ttttttctta attcctctac aacatgtggt tgttgcatca tacatccaca tacagctatt
     2821 ttcatatctg gattttttcc ttttagatgt tttaattgtc ctaagttacc atacactttt
     2881 agctctgcat tttctctaac tgcacaggtg ttatatatta ttaaatcact ttcttcaacc
     2941 atcattgaca tttggtatcc catctcttct aacattgaac ataatttttc tgaatcatgt
     3001 tcattcattt gacacccgaa ggtttgagta aacacgagtt ttctctttcc agttctgttg
     3061 aagtattctt cattttgtct gtgtatttgt tctatatatt tatcttgttc ttgtattttc
     3121 tctataggta ttgttacttg ttttcttttg ctcacgtcta ttcctcctag ttaatttctt
     3181 atattacaca taaccttaat tatatcaaat aagaaaaatc ttttaaagat attattattt
     3241 ttctagttgt gttttaatag taaatctaat gatttatata tactatattt ctaaaatata
     3301 aaatcatata attattataa taataaaaag atgttttaaa ttaaaactta aaacatcttt
     3361 ccttaaataa aatatatgat ttactattaa atacaattac atctattcat tttcaattaa
     3421 ataacaatca tttaatatta aatattgatc ttcctcaacc gttatatatc ttcttcctga
     3481 aaaagtatca ttagtaacta ttccctctgc attacctaag ctatcatttc taacttcata
     3541 atatgcatca gaagaatttg acattataat atattctcca gcaggaattt ctaatccaat
     3601 tttatacata ccatttccaa acttaccatt cttggccttc tgggctttag catactttgc
     3661 taatgtcatt gttgaatcct caattttaat atattgacca ttctttaagg tgatatatct
     3721 agtcccacta aaaatatcat ttgaaagtat actatcagca ttacctgtac tatcacttgt
     3781 aacttcataa taagaagcat aacttcctga gtttgaagtt attaagtatt cacctgctga
     3841 gatatctttt ccaaccttat acattccatc ttttatagtc tttgtagtag gtttaacatt
     3901 ttttacaacc ccagtattaa tatctccaat tccatttgtt atatttaaac actgttgtac
     3961 tatatttgaa tctatatatc ctatagaagt tatcttctta gcatttttta aaatgctttt
     4021 attgctacca tcattaacta aaaccattgg accatgtttt gataaagaag atcctacaag
     4081 tgcatttgtt aattcataag ctccagctat ataaaactct ctagcatcct tataaaactt
     4141 atttattatt gctttattag tttcaaaacg agtactcccc cctagtctag tagatttagt
     4201 attgtttact aaagtggtac tcattgaagc tgttcctcct attacataag actttaaacc
     4261 actagttgaa aaaggtatac tttgtccatt agtaagaatt attggtgctt tatctcttgc
     4321 tgctacagat gcaatactta tagcatctgc ttctccttta tatgcattgg ttagcataac
     4381 agtattgact ttttttattg aatttatttc ttttgcaaca ttataacttg tttttattct
     4441 gtcatttccc ttaattctta caactttcat tttcttagat tttaatgaat tttcgacaga
     4501 tgtactaata gaatatgttc ctccaattat ataaactttt gatacatttt ttaatcttgc
     4561 agatgtctca gttggtatag tatttttttc agttaatagt ataggggcat ttaaagctcc
     4621 tgctagtcca cttgcactta atccatctgc aatagagtta ctagtattaa ttaatatagc
     4681 agttttatat gcatttttat ctgctatttt acctgctatt tcatacttat tttttccttg
     4741 tattttttct acagatgata ttgcatctac taattgaata tttgcaaata caaaagaaat
     4801 acttaaagtc aatgttaata ttcttttata gaatttcata ataaaattgt ccccctcata
     4861 ataaattttt aatatataaa tacatattct taaattagtt atgtacttaa caaatttatg
     4921 taaaattgca aattatatta agcatattac aaataaatat taatacaatt attcatttag
     4981 ctataattgt atttacattt atattaaaaa tcaactagat ttgtataaat acttataatt
     5041 atatttttat tcttaatatt ttt
//
LOCUS       DAEPUT010000160         4565 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.164, whole genome shotgun sequence.
ACCESSION   DAEPUT010000160 DAEPUT010000000
VERSION     DAEPUT010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4565
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.164"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(11..187)
                     /locus_tag="KRL22_003780"
     CDS             complement(11..187)
                     /locus_tag="KRL22_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274202.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(241..330)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(510..710)
                     /locus_tag="KRL22_003781"
     CDS             complement(510..710)
                     /locus_tag="KRL22_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274203.1"
                     /translation="MPKFICNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(712..1062)
                     /locus_tag="KRL22_003782"
     CDS             complement(712..1062)
                     /locus_tag="KRL22_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HBH1274204.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            1224..1412
                     /locus_tag="KRL22_003783"
     CDS             1224..1412
                     /locus_tag="KRL22_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1274205.1"
                     /translation="MTKYDFNFKLKVAKFYLNREGRDILIVKQYGVYNHSQVERWVNI
                     LGECALKIKKFSILYGSS"
     gene            complement(1889..2059)
                     /locus_tag="KRL22_003784"
     CDS             complement(1889..2059)
                     /locus_tag="KRL22_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274206.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESRYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(2448..2936)
                     /locus_tag="KRL22_003785"
     CDS             complement(2448..2936)
                     /locus_tag="KRL22_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1274207.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTEGNIIWWTKKDGKITVNSGIGDEDPLAHKIENLGMPYN
                     GSYTLVSSNGSEEYLELNIIIDGEISKSGLDKLEEDYGSSIKIPNDKNMIITFLSNKS
                     DN"
     gene            3740..4114
                     /locus_tag="KRL22_003786"
     CDS             3740..4114
                     /locus_tag="KRL22_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1274208.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINSQSHYKIIDSKEYYTFKKKVLKSSKSIKIMRSLTT
                     THKNVSKEKLDLLDEYYRNLKE"
     gene            4219..4565
                     /locus_tag="KRL22_003787"
                     /pseudo
     CDS             4219..4565
                     /locus_tag="KRL22_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT         1858 a          558 c          536 g         1613 t
ORIGIN      
        1 aaaaatctgt ctaattatac ttacttacca ataccatcac ttgatgcaag caagattcca
       61 caactttttc tccgtactct aatataaaat catctaactg tgtatctata aaatcacaat
      121 aatcatatga actaccaata taagcagtta acatatgtgt acatttatcc attttatctc
      181 taaacataat gtatttatcc ccctaaaaaa ctttcatgaa aaacaaaaag aaaatatctt
      241 tttggcaact ggctgacata acttatttta taagcgttag tccctatagc tttgcgtcac
      301 taaatttctc tagttttgcc gatttagttt tattctacag attaataata caatagaatt
      361 agttattatt caacatatct agctgaaaaa ttaataaatt tatatatgaa cgttaaatta
      421 tctgaaaaaa taaaaagccc ctctatcagg agtgacttaa aaattgaatt taagtttgta
      481 tttaaaacac atttttaata atgcaaaaac taatcaaaaa taaacaattc atcaataggt
      541 gtatctacta tttttgatat atctattgct aatttcaaag aaggattata ctttcctgct
      601 tctaaacgca taatggtttc tcttctaact cctacttttt ctgctaattg ttcttgagtt
      661 aattctttta attgtctata tttttttagg ttacaaatga atttgggcat attatttttc
      721 ctctaaaata taaagtttta tagcataaac atttaaagtg attgcatatg taattgatag
      781 taaaacacac attaattcta tattcctaga cactatagta atacaccata aaatgaataa
      841 ttctataata gcaagctgtc ctgtaaatgc catagctgct ttttcatctt gtacatacct
      901 ttcatctgct ttatcaccat ttatttttgc tataataaag tttgagaaaa aagcaaaaaa
      961 tccaatatat gtaaggtcag caacattgcc agatgaaaaa tatctaagac ttaaaaatcc
     1021 aaggaaacca caaaaaccca taaaaaattt tttctgaatc attttttatc ctccttagta
     1081 attttaaaag agatatattt atatctttat gatacaaata tatctctttt atattctttt
     1141 gtcaatagaa aatcagtatt atacaatatt tgcactgcag cataattgtt agagcaaaaa
     1201 tctactgctt gagatgttta tgtatgacta aatatgattt taatttcaaa ttaaaagtag
     1261 ctaaatttta tttgaataga gaaggaagag atattttaat agtaaaacaa tatggagttt
     1321 ataaccattc tcaagttgaa agatgggtta atatattagg agagtgtgca ctaaaaataa
     1381 aaaaattttc tatactatat ggttcaagtt agatgttata aactatatga tgataactaa
     1441 atatagtgta caataaatcg ctaagtattt tggaataaac aatagcgcag ttatagtaac
     1501 atgaaaataa aaatttttac atagtggtgt tgatgccttt tccaaaatga aaggaagacc
     1561 ataatgaata aaaacaaaaa cactaaagaa aaaataaatt aacaagagaa caagaattag
     1621 aatatgaaaa taaattttta aaagatgagc ttgagttttt aaaaaagatg tgtgtctcag
     1681 ggaagccaca ttaaaaaaca gtggtatcat tattaatcaa aagaaagtta gatgtattat
     1741 caaaaaatta gaacttaaat gcatagcatt ttttcataaa tcacataaat ataactccta
     1801 taaaggtata attggaaaag taaaaaataa taaaacaaat agaagattta aaacatcaat
     1861 agcatatcag aaaataacaa atgatatgct agaatttata aaatatatct aatgataaaa
     1921 atggaaaatc aattataaaa aaggcatatc tcgattcatt ttttgttata tagtcaaata
     1981 agaatactat agatgaaaga tacgattttg catatgtatt aagtaagtat tctgatgttt
     2041 ttggttgata cacatgcaat aaagaagttg tgtttgcaga taaattagca aaactatagt
     2101 ataagttgca acaataaaga aaatgaaaat tatcatacta aagcataagg catgttacaa
     2161 ttttattaga taggacatta acatacacta aagtactttt tattataaag agtacttatt
     2221 tttttgaaat tcattaatgt ataaactatc aagaatatta ctcaacataa tttaaaaaca
     2281 acttgaatag gtatttttaa attatgtgat ataataaaaa atagaagtgt atgccaatac
     2341 acttctgtag ttataactaa gcattctatt cttgaggagt gcttttttca tttttataac
     2401 caactctttt tactttaaca ataattatca gacctatata tttattttta attgtctgat
     2461 ttattagata aaaaagttat tatcatattt ttatcatttg gtatttttat tgaactacca
     2521 taatcttctt ctaatttatc tagaccactt ttacttattt ctccatctat aattatgttt
     2581 aattctaagt attcttcact accattagat gacactaaag tgtacgaacc attataaggc
     2641 atgcctaaat tttctatttt atgtgccaaa gggtcttcat caccaatacc agagtttact
     2701 gttatttttc catctttttt agtccaccat attatgtttc cttcagtata ttttgattca
     2761 tctgcatagt agctaagaga cgcacttttt attgcactta tatcagcttc aagtttagct
     2821 atctttgctt tttctatatt tttaaataat gctggaagtg ctactattgc caatattcct
     2881 attatagcaa ttactactaa taattccact agagtaaatc cttttttatt tttcatttat
     2941 ttcccctcca tataaaatta ataatatata aatttttatt ttgttgattt ctactttcta
     3001 tattttacca tatatagaca aaaaaatcac tttctatgac aaatatacta ttattttaca
     3061 atttatggaa atgatttaaa atgacatttc ttgttagaaa agatataaga aatggattaa
     3121 aataaagaaa actacagtca tatcaatgtc aataatatta tttaaaagca gatgaaaata
     3181 aaaagaggac tcagaaaata atgtctattt aattatactt acttaccaat accataactt
     3241 gatataaaca agattatact acattttttt atgctctagt ataaaatcat ctaactgtgt
     3301 atctataaaa tcaaaataat tatatgaact atcagtataa taagtcaaaa tatgtataca
     3361 tgaatacata ttttaaaaga tatatattat tacataccta aaaaactttc ataaaaacaa
     3421 aaataaaata tgcttttagt aacttgttaa cataacttat aatttatttt ataagcatta
     3481 gcctatatag ctttgtgcta ctaaatctct ttgattctaa cgatttagtg ctattctaca
     3541 actaaaataa tacaatagag ctatttattg tttggtagca ttgtttgtaa attaaacaaa
     3601 tttatacata tgaatattat tttacgttca aaaaaacaga ctaaatatgt agaatatttg
     3661 gtaaaactta cctctagttt ttgtcttaaa aagctcctat tattaactta agttagaaga
     3721 attaaggaag tgacataaat tgaaagaaga aatattaata gaaaaattat taagagcaga
     3781 attaatagta atggagtatt tatggaaaaa agacactcta atgcctaaaa aagaaattgt
     3841 aaaagaaata aaacagattt atggatggca taaaagtaca ataaaaatac tactaaaaag
     3901 gctagttgct aaaaggtatt tggctagata tattataaat tctcaatctc attataaaat
     3961 aatagatagt aaagaatatt atacttttaa gaaaaaggta ctaaaatcta gtaaaagcat
     4021 aaaaataatg cgttcactta ccactacaca taaaaatgta agtaaagaga agttagacct
     4081 attagatgag tattatagaa acttaaaaga atgatatagt aaaaatcgaa tgtaattatt
     4141 taccttaatt cttttgtttg taaaacttta ttgatacaga atttaacata tacataaatt
     4201 ggtaaaggaa tgtatactat gaaaattagt aaattaccag aagcggaatt aaaagttatg
     4261 agatatattt gggaatcaga aaaggtatta atatcaagag aaatcaccaa gtctatggaa
     4321 caaaaatatg aatggaaaga tacaactata tttacagtat taaaaagatt actaaagaag
     4381 agagttttta gaaacggaga aaatagataa gtgtacacac tataatgtat tagtaaaaaa
     4441 aaataatatc agagatttta aacaaaagaa tttttaaaga atacacataa aaattcaata
     4501 ttaagtttaa tgtcagcact atgtagtaag gatgatgaag tagatggtga tattttaaat
     4561 ttatt
//
LOCUS       DAEPUT010000161         4372 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.165, whole genome shotgun sequence.
ACCESSION   DAEPUT010000161 DAEPUT010000000
VERSION     DAEPUT010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4372
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.165"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            231..1310
                     /locus_tag="KRL22_003788"
     CDS             231..1310
                     /locus_tag="KRL22_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH1274209.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKTTKTRLEYGIDYMKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1634..2002
                     /locus_tag="KRL22_003789"
     CDS             1634..2002
                     /locus_tag="KRL22_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH1274210.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVERVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2119..2916
                     /locus_tag="KRL22_003790"
     CDS             2119..2916
                     /locus_tag="KRL22_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1274211.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKFLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQL"
     gene            3315..4205
                     /locus_tag="KRL22_003791"
     CDS             3315..4205
                     /locus_tag="KRL22_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1274212.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFDAVKELNDSGIFCGILLTPMLPFLTDTKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKEIIKAYKRSESYTQIKFF"
BASE COUNT         1665 a          486 c          825 g         1396 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaatttat atggtttata gtttaacagt aggaaatatc
      121 gtatgagtaa gactatcata ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagtatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cataaattgg gatttatcta
      541 taagtgcact agaaagaaat actgagtatt ggtcttcaga atttgctgta agagcattta
      601 tcatcaagga tgaagagcgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggtt gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacctg tactacctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgcaaagg attggtacgg taaaaataaa tccactaact
      901 ggattgtaaa gcatggttgc agaactctgc taaaaaaagg caatcgtgat gtattagccc
      961 tttttggata tgatgatact acttctataa atcttcagga ctttacttta gaaacaacgt
     1021 ccatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaaacgacaa
     1081 aaacaaggct cgagtacgga attgattata tgaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatacactcg attgctatta
     1261 ttattaatgg tatagaaaaa gataaacttg attttgaatt aggtatataa ttttactaac
     1321 agaataatct atatcagata ctttgctaaa cttatataat atattttact aaatttatat
     1381 taggtagttt actacttgtt tactgaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagcc atataaatta gaatttgtag
     1621 aggagaaatg taaatggatg tatatagttt ttggaatgac actttggcac aagatgctgt
     1681 taagataaga aaatattttc atgaagatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaagg gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaacca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggatga tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtgtttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccaa atacagtact tttcaaaaaa tcataatgta
     2281 ttggtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gataaacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaatttttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgctgaaa
     2641 atgttagaag gctacgaaaa aaaagaactg tgtcatctca tgtatctggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaataa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttataatata taaaaattac atacccatta
     2941 ggtaaattat gtagtatatg tgtttacaga tggttataga aataaatatg taataaacta
     3001 cttaacactt aaaaagtgga tttgtccaga gtataataca aagcatgata tatataaatt
     3061 tttaagcgaa atacatcaaa agaaggatta gaattagtgg agacagaaca gctattatag
     3121 attataaata aatagtttta aaggagaggt actacgaata tagaggaagg taaatcatac
     3181 gttattcaag tattataaat gattagttta aaagtactat cgaataggag tctccatatt
     3241 taaaccttag taaaggtagt taaagtagta gtttaaaaac taaaaaatta tataaaggaa
     3301 ttaggtataa gaaaatgatt gagagtatac cagcaaaaca aattttacaa aaagtgaaat
     3361 ttgacaatac aagatggttt ggaattgact ataatatgaa tctctatcgt ggttgttctc
     3421 atggatgtat atattgtgat agccgtagca caatatacaa catagagaat tttgacaaag
     3481 ttagatataa agaaaatgtg atagaaattt taagtaaaga attgcgttca aaaagaaaaa
     3541 aaggggtagt aggcattgga gctatgtctg acacatataa tccttttgaa aagcaacttt
     3601 gtattacaaa gcaggcacta gatttgattt cggaaaatca ttttggagtg tctattgata
     3661 ctaaaagtag tttggtggtt agagatatac cgattttgca gaaaattaaa aaaaataatt
     3721 ctgctattgt aaagttgact ataaccactg caaatgatga attatcaaag aaaatagaac
     3781 cttatgtaaa tccaagttct gtacgatttg acgcagtgaa agaacttaat gattctggaa
     3841 ttttttgtgg catattatta actcctatgc ttccattttt gactgatact aaagatgaaa
     3901 tacgagcaat tgtagaaaaa gcacacaagg ctaatgcaaa atttatttat tgtatgtatg
     3961 gtgtaacaat gcgtagtggt cagcgagagt ttttttatga gcatttaaga gatatatcac
     4021 caaaattggt acttaaatat cagaaaacat atggtttaaa ctatgtatgt actgtacaaa
     4081 ataaagattg ttgtgagaag ttgttaagag aagaatgtgc acgttatggt attttgacgg
     4141 atatgaaaga gattataaaa gcgtacaaga ggtcggagtc atatactcaa ataaaatttt
     4201 tttaagatag gctttggatg agatataata gtggtgattg atgtgttgat attatagttg
     4261 attgttagag aggatattat agatgaatat tagtattgat attttaggta attgctagag
     4321 ctgatattat agatgaatat tagtattgat attctaggta attgctagag ct
//
LOCUS       DAEPUT010000162         4364 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.166, whole genome shotgun sequence.
ACCESSION   DAEPUT010000162 DAEPUT010000000
VERSION     DAEPUT010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4364
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.166"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            59..844
                     /locus_tag="KRL22_003792"
     CDS             59..844
                     /locus_tag="KRL22_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1274213.1"
                     /translation="MLKLIKCEFYKFKRRSLFVLATLVALVFPVVMTALYWNIPTQVN
                     YDNLFSGIVDYGDFLLLLPILVVIATSLFFTETDNDTLKNLTTIPISKSKIVVAKIGV
                     MAIISVAYTLLGFFASVLCSKILGIAMENMAQKFVLSIGLGIMLLAAALPCVALVVWF
                     NKSDLISIVITLFYTIINYVIHVTDIGMLTPVGVNIGTILPIPVINRWIYQFYDEGNG
                     AAAEFYNTMRPYFVPTHICVCIIALFLFVSIYAIIKIYNRREI"
     gene            856..1674
                     /locus_tag="KRL22_003793"
     CDS             856..1674
                     /locus_tag="KRL22_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1274214.1"
                     /translation="MLAFITTEFQKLKRYSIILVGMLGVACSPIISIVMQKIMTDEAK
                     NVLNYTFPDLLNSTIWNNMTMFFPMIIALIGGYMINREYTDDTLKNLQVIPISFPKLM
                     IGKLTTIGLLSILLGLCNSFVTIIVGIIACRENMTLSTIIIGTIQICGMALFTFIGEM
                     PLIAHCGKKQNSFKGGAVAAFLLGYISIYFKNPIIRNLYPLSAGLSIVGFNGEGFVTD
                     TTGAYSSSQSILLGVLTMLAMLILSLIIISIPQKETLATPLSQKRRKTERKIAK"
     gene            1671..2129
                     /locus_tag="KRL22_003794"
     CDS             1671..2129
                     /locus_tag="KRL22_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274215.1"
                     /translation="MKKLIPLFLMLCCLVSVTACSKDEIVSNYNQALQSIGDKGLTDD
                     KDLQGKREFGIDSYVGNYTADYDDFSGNEIIFGGTALERDNGNKIEISCDIAAQTGNL
                     KLILQTGTDEPKILCDTESSYNDTIELPSASNYVLIEADNFTGSLKLKLK"
     gene            2149..2412
                     /locus_tag="KRL22_003795"
     CDS             2149..2412
                     /locus_tag="KRL22_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012104160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274216.1"
                     /translation="MKEKILSIISLVTIFVPLTMLFVWKPTAANATAIAIGYGVFIVA
                     SFLYALFLFLKKQQRDIYVKVGLGVNAFYLLGILFMVIIPRLF"
     gene            2869..3309
                     /locus_tag="KRL22_003796"
     CDS             2869..3309
                     /locus_tag="KRL22_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016283905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1274217.1"
                     /translation="MTPNRREFEKQCAFQKFCKSVLHNEACNAHEEIRRRRVREVTFS
                     DLALHEERQLYTVDKYFQDEEAEPSYQMAGKEITPKLLLEAIRALPEERRKIVLLYYF
                     EGLTDIEIGKQLNISRSTVQYRRTSSFEQLKKYLEENADEWIEW"
     gene            3290..3547
                     /locus_tag="KRL22_003797"
     CDS             3290..3547
                     /locus_tag="KRL22_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019727567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274218.1"
                     /translation="MNGLNGKPTEYPENTLVPYPVILAASKGDPDAMKIVLQHFSGYI
                     ARLSMRKLYDERGNVYFGVDEEIRERLQTKLMRAILTFKAE"
     gene            3966..4169
                     /locus_tag="KRL22_003798"
     CDS             3966..4169
                     /locus_tag="KRL22_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family DNA-binding protein"
                     /protein_id="HBH1274219.1"
                     /translation="MNNNDVPIWEKYTLTIEEAAKYFRIGESKLRKLAEENPVPDWVM
                     MNGNRIQIKRKQFEKMIDTVDAI"
     gene            4249..>4364
                     /locus_tag="KRL22_003799"
     CDS             4249..>4364
                     /locus_tag="KRL22_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005343085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH1274220.1"
                     /translation="MSEKRRDNKNRILRTGESQRKDGRYAYKYIDTFGKPQFV"
BASE COUNT         1372 a          765 c          897 g         1330 t
ORIGIN      
        1 catacttgtg aagaaagcct tgaagattat ttcaagcgtg tgacaggagg cgagggaatt
       61 gcttaaactg attaaatgcg aattttacaa atttaaacga cgttctcttt ttgttttggc
      121 tactcttgtt gctttggttt ttccggtagt aatgactgct ttatattgga acattccaac
      181 acaagttaat tatgataatt tgttttccgg cattgtggac tatggcgatt ttcttctttt
      241 gttgccgata ttggttgtta ttgcaacttc tctgttcttt acagaaacag ataatgacac
      301 tttaaagaac cttacaacca ttcctattag caaaagtaaa atagttgtag caaaaatagg
      361 agtaatggct attatttcag tagcttatac tcttttaggc ttttttgcca gtgtgttgtg
      421 ttcaaaaatc cttggtattg ctatggaaaa catggcacaa aaatttgtat tgagtatagg
      481 attgggaata atgctcctag ctgcggcttt accttgtgtg gcattagttg tatggttcaa
      541 taaaagtgac ttgatttcta ttgtcattac ccttttttac acaattatta actatgtaat
      601 tcatgtaaca gatataggaa tgctgacacc agtaggggta aatataggaa caatcttacc
      661 tatacctgta atcaatcgtt ggatttatca attttacgac gaggggaatg gagccgcagc
      721 tgaattttat aacactatgc gtccttattt tgtcccaact catatatgcg tctgtattat
      781 tgcgctcttt ctgttcgtat caatttatgc gattataaaa atttataatc gtcgtgagat
      841 ataggaggtg tgaatatgct tgcttttatt acaacagaat ttcaaaagct aaaaagatac
      901 agtattattt tggttggtat gcttggtgta gcgtgttccc ctattatttc aatcgttatg
      961 caaaaaatta tgacagatga agctaaaaat gtcttgaatt atacatttcc tgatttactt
     1021 aatagtacga tttggaataa tatgaccatg ttttttccta tgattatagc tttgattggt
     1081 ggctatatga ttaaccgaga atacactgat gatacactaa aaaatctgca agttattcct
     1141 atttcttttc ctaaactgat gattgggaag ctaactacaa taggactact ttctatactt
     1201 ttaggattat gtaattcatt tgtcactatt atagtcggaa taatcgcttg tcgtgagaat
     1261 atgactttat caacaattat aattgggact atacaaattt gtggaatggc attatttaca
     1321 tttattggag aaatgccact tatcgcacac tgtggaaaaa aacaaaactc tttcaaaggt
     1381 ggggctgttg cagcttttct attaggatat attagtatct acttcaaaaa tcctattatc
     1441 agaaatttgt atccgctctc tgccggatta agtatagtcg gctttaacgg agaaggattt
     1501 gtgacagata ctaccggagc ttattcatct tctcaaagca ttttattagg tgttttaacg
     1561 atgttagcta tgcttatatt atcattgata ataatttcta ttccacaaaa agaaacttta
     1621 gctacccctt tatctcaaaa aaggagaaaa acagaaagga agattgcaaa atgaaaaagc
     1681 tgataccttt atttttaatg ttatgttgtc ttgtttctgt aactgcctgt tctaaagatg
     1741 aaattgtaag taattataat caagccttac aatctattgg agataagggt ttaacagatg
     1801 ataaagattt gcaaggaaaa cgtgaatttg gtatagatag ctatgtagga aattataccg
     1861 ctgactatga tgatttttcc ggtaatgaaa tcattttcgg gggaacagct cttgaacgag
     1921 ataatggaaa taaaatagaa atttcttgtg atatagctgc tcaaaccggg aatttgaaac
     1981 taattttaca aacgggaact gatgaaccga aaatcctttg tgatacagaa agctcatata
     2041 atgatactat tgaacttccg tctgcaagca attatgtttt gattgaagca gataatttta
     2101 caggttcact gaaattaaaa ctcaaatgat aatagaaagg aaaccattat gaaagaaaaa
     2161 attttaagta ttatatccct tgttacaatt tttgtacctc ttactatgtt atttgtttgg
     2221 aagcctacgg ctgcaaatgc aacagctatt gctattggtt acggtgtttt tattgttgcc
     2281 agttttcttt acgcactatt cttatttctc aaaaaacagc aacgcgatat ttatgtaaaa
     2341 gttggattgg gtgtaaatgc cttttatcta cttgggatat tatttatggt tataatccca
     2401 cgtcttttct aaaatttaaa atctaaatat ctgccggacg acggcaaaag aaaaaaagcc
     2461 gtcgcagagc agatacattt tcacgcgcct ttgaagcggt ggctttgatt tttaaagccg
     2521 ccgcttcttt ttgtctactg ctacctataa cataaattag cggcatttag gagggctgcc
     2581 gctatgggaa tttctttgct gttatacagc atacataggt tgcattcatt aaaaaaagta
     2641 cagttccacc accgggtaag tctggttata gatatgaact gtcaaatcaa ttaaataccg
     2701 ctgttatttc ctatgcgcct atctgcgttt tgcaggcagg cgcattttgc attttacaga
     2761 agatttttca aaaactttgc tctctttttg gcaaagcaaa aagtcgcctg tattatcccg
     2821 cgaaaagggg aggtactacc gcctttcggc agaaaggagg tgaacaccat gacacctaat
     2881 cgcagggaat ttgaaaagca atgtgcgttt caaaagttct gtaaatcagt gctgcacaat
     2941 gaagcgtgca acgcccatga agaaattcgt cggcgcagag ttcgggaggt tactttttct
     3001 gaccttgcct tgcatgagga acggcagctt tataccgtcg ataagtattt tcaagacgaa
     3061 gaagcagagc cgtcttatca aatggcagga aaagaaataa ccccaaaact gctgcttgaa
     3121 gctatccggg ctttacccga agaacggcgc aaaattgtac tgctgtatta ctttgaggga
     3181 ttaactgata tagaaatcgg aaagcagctc aatatctcaa gaagtacggt acagtatcgc
     3241 cggacaagct cctttgagca gttaaaaaaa tatttggagg aaaacgctga tgaatggatt
     3301 gaatggtaaa ccgaccgagt acccggagaa cacccttgta ccttatcctg tcatactggc
     3361 agcgtcaaag ggcgacccgg acgcaatgaa gattgtattg caacatttca gcggctacat
     3421 agcccgtctt tccatgcgaa agctctatga tgagcgagga aatgtttatt ttggagtaga
     3481 cgaagaaata cgcgaaaggc tgcaaacaaa actgatgagg gcaatcctca catttaaggc
     3541 tgaataaacc aacgcggtat tggaacgctt cccccttttc tgttccatat cgcagaacag
     3601 ccctctgctc tttgataaag aaagcggcgc aatagaacgg cgacgcagta taaggcaaat
     3661 cggatacgtt ccttttgtgc cgagccatgc ggtggatacg ccatgacctt tctcttaata
     3721 gaaaagcgag cgagaaatac cacaccgtaa agcagagata gcagcctgcg ggcgataacg
     3781 cacagaatac ataatgatac ttccttatag ccatagtccg agcgttagaa gcgtcgcagg
     3841 caatgggtag ggcttcggca gaccgccgga ggggtgcaag tcccatgagg ttacgctaat
     3901 agccgtccga ttaaagccta tgttacagat tgatttttga cccattaaga aagggggacg
     3961 acaaattgaa caataacgac gtgccgattt gggaaaagta cacgcttacc atagaagaag
     4021 cagcaaaata tttccgtatc ggagaaagca agctgcggaa actggcagaa gaaaatcccg
     4081 tcccggactg ggtaatgatg aacggaaacc gtattcagat taagcgtaag caatttgaaa
     4141 aaatgattga tacggtggac gcaatctgat agtgaaatcg agccttgaat gtggtacaat
     4201 atagtcaagc atatcaaggc tctttccatt atggaaagga gcataacgat gtcggaaaaa
     4261 agacgggata ataaaaatcg tattctccgc accggagaga gccagagaaa agacgggaga
     4321 tatgcctaca aatatataga tacctttggg aaaccgcagt ttgt
//
LOCUS       DAEPUT010000163         3996 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.167, whole genome shotgun sequence.
ACCESSION   DAEPUT010000163 DAEPUT010000000
VERSION     DAEPUT010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3996
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.167"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            218..1723
                     /locus_tag="KRL22_003800"
     CDS             218..1723
                     /locus_tag="KRL22_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH1274221.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            1837..2535
                     /locus_tag="KRL22_003801"
     CDS             1837..2535
                     /locus_tag="KRL22_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH1274222.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            2820..3908
                     /locus_tag="KRL22_003802"
     CDS             2820..3908
                     /locus_tag="KRL22_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274223.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTAVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
BASE COUNT         1584 a          396 c          645 g         1371 t
ORIGIN      
        1 taaaatcgat acaataatat agaagtaata aaaaaatagt taatataaaa gtgatacaat
       61 aataatagaa gtaataaaaa aaaataatta atataaaaat gtgtacaaac taatgaatat
      121 tgatatagta agctatcata tgaaagagta tgtacacatt ttttttacta atttttcaca
      181 atatgaacat aaataattta caagaaagga atcttttatg aaaattcaaa atactgagtg
      241 gggatatatt gaatggaaac atacttatga tgaaaataat ccaaaacaag ctatgaatat
      301 atacattgca gtaactatgc ctggtaagaa acattttaat catgttcatt atggtcaaga
      361 gcagatgata tatattttag agggagaggg tttgtatatt ataaatggag tttggaagcc
      421 attttatcaa ggtatgattt tttatataga atctggtagc acacatgaaa ctataaatac
      481 aggtgataga gaaataaaag aacttattgt ttcaaataat gtagatgatg taggagagag
      541 tgaagttata gatattaatc ctaataatta tttaaagaag accttgataa attatagtga
      601 aagtacatta aatttgtatg cagcagtaga atcaattcgt ggtcaattta tagacccgtt
      661 taaaattcca ttaattatat atgatgattc atggaatata gttttaaaaa atccttattt
      721 tccacttttt tgttttgaaa aatgtaatcc tatgaaattt cctcaaaatt gtgattgtat
      781 gaatcaaaaa agtagcaatc aatttgtatg tgaatatggg ataactatat ataatatacc
      841 aatactgtac aaaagcaata gcataggtgt tataagagga gggtatgtac tattatctga
      901 tttgaattta gatacagagc ataataattt atatgatatt ccagagggag ctgctagaag
      961 tataaaacgc ctcctgaaac aaatatctaa aaatataata aatttttgct cttttaatga
     1021 tataagaaag gatttacaag aaaaagagaa gactatagca agaacatatc attatggaga
     1081 gcaacttgaa atgaatttaa aagtagctca agatatggtt actaatttaa gaataaatca
     1141 tcacttttta tttaatacat taaattcaat ggcaagcata gcactagatg atggtagtta
     1201 tgatttgtat agtgcaataa tagatttatc aagaatgttt agatatacaa tgaggtctga
     1261 tttaagattt gtagaattag aatctgaaat attatacatt aaaaattatt tgaatttaca
     1321 gaaattacgt tatggagatg cacttaaagt aaaatatctt attccagaga agttatataa
     1381 cctttctgtg ccttttaact ttattcaacc tattgtagag aatgcattta cacatggatt
     1441 tagagatatt gacacagaaa agcgaattga aataattgca agattagatt ctcagtatgc
     1501 cattatagag attcataata atggaactat cttagatgga aataatatag acaaaataaa
     1561 ggcaggtatt cgtagtaata atggtcatgg tttgtcttta atatatacaa aattcacatc
     1621 tgcttatgga aataattttg atatggatat aaagtcgagt gataatgaag gaacttacat
     1681 aatgattaaa attcctattg aaaattataa ggagtatgta tagaacttgt gaaaaattaa
     1741 taagttttat aaatgttaag aaatatatta gatgttttta tgttgtttta tatatcttac
     1801 ttttttatat tattaagcta aaagggaggt attctcatga gaagagcact aataatagat
     1861 gatgaagaag ctgttctaaa aataataaca cattttatag aaatgaaaga tatgccaata
     1921 aaaattgttg gtaaagcaac atctggtgat gaagcagtag ataaaatcat tggtttagag
     1981 ccagacatag tttttataga tattcaaatg ccaatataca acgggttaga agtaatagaa
     2041 aaaacatctc atttatctaa aaaaataaac tttgtagtaa taactgcatt taactatttt
     2101 gaatatgctc aaaaagcttt gagattaaat gtaaaagata tactccttaa accattggat
     2161 atgaaagaat ttactaagtc tgtagaaaaa attattggat atcaatatac caataatgat
     2221 ttattaaatg agatactgga atatataaat ctaaactata gcaatgactt aaagttaaat
     2281 gattgtgcta gattattttt aaccaatcca tctaatatat ctaggatttt taaaagtaat
     2341 ttaaatacaa cttttatatc atatctaaat catataagaa tagaaaaatc tattgagtta
     2401 cttgaaaata ctacaaaaag tataaatgag attgcagaaa tagttggata taatagccta
     2461 aataactttt ataaaaactt taagatagaa aaaggaatga ctccaaaagt ttataaactg
     2521 aacactaaaa attgaaattg ataaataaaa agtcaatata gataattgtt tgagtgtgtc
     2581 tgaataagta tactttaatt atgataaaaa ttaaagcgct ttaaacatat ttaataatat
     2641 taaaccttat aaaagctgta cctatttata taaaaaaata tatataaata aaaagaaaaa
     2701 gatatacaaa ataaaaaaag tgaattaaat actgcttcaa aaagacagaa ttttcattta
     2761 atttactgag agtttatatt tcttaaagga aggtaacttt ataatggagg taatttaata
     2821 tgtcagacaa agtgaatatg aaaaatatta tctgtattgc aggcgcttat ctagcaacag
     2881 caattggttc tgggtttgct actggtcaag aaattctaca attttttgcc tcacaagggt
     2941 atatgggttt aattggagca ttaatatcaa tggtattgtt ttcatttctt ggtgctgaag
     3001 ttataactag aggtagagag ttaaaactta aagaaccaac aagaatttac actttttatt
     3061 gtgggaagat tttaggaaaa ttttacgaat ggtttagtcc aatattttta tttgggattc
     3121 ttatagtaat gatttcaggt gcaggctcaa ctttaactga atactatggt ataaatcctt
     3181 acttaggaag agtattgatg gctgttgcta ctttaattac agtgtctatg ggtttagaaa
     3241 aattagtaag catacttgga cgtattggac cagtgatagc agtatttaca attgctgttg
     3301 gattaataag cttgtttaag cattttgatg gtttatctat ggttggagaa gctatgaaaa
     3361 atattgaagt tacaaaagca tcagaaagtc caatcgtttc tggtgtaata tataatacat
     3421 taaatattat tgtaatgatt gtttttttaa caggaatggg agcttctatt gaaagtaaaa
     3481 aggatgcttt ttggggaggt ttattaggtg gaatagtgtt tatgactgct ggtatagtta
     3541 tgtatttggc tatgatttca gatataggaa atttgtatat gaaagaaata ccatcacttt
     3601 atttagcaga taatatatct cctattgtag gtgtatgttt ttcagttgca ttaatattag
     3661 gtatctacac aacagctgtt ccacttttat ggtctgtaac caatagaatt gttgaagatg
     3721 aacatcctaa atttaaattg gtaacagcag taatagctat tttggcttgt ataggaggtt
     3781 ttttaccgtt tggtaaatta gtaaacattt tatatccata tacaggttat atggggcttt
     3841 taattttagt ctgtatggtg tataaagcaa ttacatgtag aaaaaaatca acacaaagtc
     3901 aggaatagag ccacttatta atagttttta tttaaagaaa ttttttatat aatccgaatt
     3961 taaaaagtca aaatagttaa ataaattgca aaacat
//
LOCUS       DAEPUT010000164         3518 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.169, whole genome shotgun sequence.
ACCESSION   DAEPUT010000164 DAEPUT010000000
VERSION     DAEPUT010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3518
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.169"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(22..1512)
                     /locus_tag="KRL22_003803"
     CDS             complement(22..1512)
                     /locus_tag="KRL22_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBH1274224.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KKSMIGGRGVVLTSEEAIHENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTLIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKLVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREALGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALSEFFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
     gene            complement(1907..2146)
                     /locus_tag="KRL22_003804"
     CDS             complement(1907..2146)
                     /locus_tag="KRL22_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274225.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSLIESGKSDPTL
                     KTLERIAELTNSTLVIDLIPNELEQVELQIEEEKQ"
     gene            complement(2390..2563)
                     /locus_tag="KRL22_003805"
     CDS             complement(2390..2563)
                     /locus_tag="KRL22_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine methyltransferase"
                     /protein_id="HBH1274226.1"
                     /translation="MSKYCLFLIVIYYLTGGNNSMSRFCKFGKLHVTKGNVDKLLGIL
                     LTASKELKRSGPH"
     gene            complement(2508..3245)
                     /gene="erm(B)"
                     /locus_tag="KRL22_003806"
     CDS             complement(2508..3245)
                     /gene="erm(B)"
                     /locus_tag="KRL22_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBH1274227.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(3370..3453)
                     /locus_tag="KRL22_003807"
     CDS             complement(3370..3453)
                     /locus_tag="KRL22_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBH1274228.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
BASE COUNT         1040 a          618 c          550 g         1310 t
ORIGIN      
        1 caattaaaac ttcttccatt ttcagcctgt atcatagcta aacaaatcga gttgtgtgtc
       61 cgtttttggg cgttctgcta gcttgtttaa agtctcttga atgaatgtat gttctaagtc
      121 aaaaaactct gacagcgcct ttatatagct ttctttttct tcttttttta ctttaatgat
      181 cgatagcaac aatgatttaa cactagcaag ttgaatgcca ccatttcttc ctggtttaat
      241 cttaaagaaa atttcctgat tcgccttcag taccttcagc aatttatcta atgtccgctc
      301 aggaatgcct agcgcttctc taatctcttt tttagtcgtc accaaataag gcttgtatac
      361 atcacttttt tcgctaatat aagccattaa atcttctttc cattctgaca aatgaacacg
      421 ttgacgttca cttctttttt tcttgaattt aaaccaccct tgacggacaa ataaatcttt
      481 actggttaaa tcacttgata cccaagcttt gcaaagaatg gtaatgtatt ccctattagc
      541 cccttgatag ttttctgaat aggcacttct aacaagttta atcacttctt tttcttctaa
      601 gggttgatct aatcgattat taaactcaaa catattatat tcgcacgttt cgattgaata
      661 gcctgaacta aagtaggcta aagagagggt aaacatgacg ttattacgcc ctattaaacc
      721 cttttctcct gaaaatttcg tttcgtgcaa taagagatta aaccagggtt catctacttg
      781 ttttttgcct tctgtaccgc ttaaaaccgt tagacttgaa cgagtaaagc ccttattatc
      841 tgtttgtttg aaagaccaat cttgccattc tttgaaagaa taacggtaat tgggatcaaa
      901 aaattctaca ttgtccgttc ttggtatacg agcaatccca aaatgattgc acgttagatc
      961 aactggcaaa gactttccaa aatattctcg gatattttgc gagattattt tggctgcttt
     1021 gacagattta aattctgatt ttgaagtcac ataaactggc gtttctaaaa caaaatatgc
     1081 ttgataacct ttatcagatt tgataattaa cgtaggcata aaacctaaat caatagctgt
     1141 tgttaaaata tcgcttgctg aaatagtttc ttttgccgtg tgaatatcaa aatcaataaa
     1201 gaaggtattg atttgtctta aattgttttc agaatgtcct ttcgtgtatg aacggttttc
     1261 gtctgcatac gtaccataac gataaacgtt tggtgtccaa tgcgtaaatg tatcttgatt
     1321 ttcgtgaatc gcttcttcgg aagtcagaac aacgccacgt ccgccaatca tgcttttttt
     1381 tgagcgatac gcaaaaatag cccctttgct tttacctggc ttggtagtga ttgagcgaat
     1441 tttactattt ttaaatttgt actttaacaa gccgtcatga agcacagttt ctacaacaaa
     1501 agggatattc attcagctgt tctcctttct tacgaaaatt aattagttag aagctacgat
     1561 caaagttgaa tcacaacaaa aaaggcaatc aactaagttt ttcttaattg attgcctggt
     1621 atcttcttaa agacttgaaa ttccctcaaa aacccgatat aatgggttta cagatattta
     1681 agtatctgat taataaagta attaaatact ttaccaaatt tcgggtctcg acttctttaa
     1741 ttgattggtg gtaatcaatt aaggctcgca acttattttc ttggcggaaa ataagttggt
     1801 cgtggctctt tttttgtatt ctttattcag ttcgttgttt cgttatatct agtataccgc
     1861 ttttaaaaaa aataagcaac aatttcgtta aatatattaa cgacaatcat tgcttctctt
     1921 cttctatttg caactctact tgttctaatt cattaggaat taagtcaata actaaggttg
     1981 agtttgtcaa ttctgcaatt cgttccaatg tttttaatgt cggatctgat tttcctgatt
     2041 caatcaatga ataatttgat ctactcattt ctaattcttg ggagaatttt tcttttgatt
     2101 tggtacctct catctttttt aagctttctc taaatgctag ttccaagttt ctccctcctg
     2161 tttatgtaaa tattttgcac gttttccatt taattatatc gttacacctt gtaaatcaca
     2221 agtgattaat cacaaatcac ttgtgattag tgattgttat tggtgttgcc tagaacgatt
     2281 ctaagcacat gtttaatttt aaagtgggca attatcttta aaatgtccta caatgattca
     2341 ataaaagcat ggctgctagt gaaacttgcg accatgcttt taaaaatact taatggggtc
     2401 ccgagcgctt tagctccttg gaagctgtca gtagtatacc taataattta tctacattcc
     2461 ctttagtaac gtgtaacttt ccaaatttac aaaagcgact catagaatta tttcctcccg
     2521 ttaaataata gataactatt aaaaatagac aatacttgct cataagtaac ggtacttaaa
     2581 ttgtttactt tggcgtgttt cattgcttga tgaaactgat ttttagtaaa cagttgacga
     2641 tattctcgat tgacccattt tgaaacaaag tacgtatata gcttccaata tttatctgga
     2701 acatctgtgg tatggcgggt aagttttatt aagacactgt ttacttttgg tttaggatga
     2761 aagcattccg ctggcagctt aagcaattgc tgaatcgaga cttgagtgtg caagagcaac
     2821 cctagtgttc ggtgaatatc caaggtacgc ttgtagaatc cttcttcaac aatcagatag
     2881 atgtcagacg catggctttc aaaaaccact tttttaataa tttgtgtgct taaatggtaa
     2941 ggaatattcc caacaatttt atacctctgt ttgttaggga attgaaactg tagaatatct
     3001 tggtgaatta aagtgacacg aatgttcagt tttaattttt ctgacgataa gttgaataga
     3061 tgactgtcta attcaataga cgttacctgt ttacttattt tagccagttt cgtcgttaaa
     3121 tgccctttac ctgttccaat ttcgtaaacg gtatcggttt cttttaaatt caattgtttt
     3181 attatttggt tgagtacttt ttcactcgtt aaaaagtttt gagaatattt tatatttttg
     3241 ttcatgtaat cactcctgaa gtgattacat ctataaataa atacagaagt taaacgattt
     3301 gtttgtaatt ttagttatct gtttaaaaag tcataagatt agtcactggt aggaattaat
     3361 ctaacgtatt tatttatctg cgtaatcact gtttttagtc tgtttcaaaa cagtagatgt
     3421 tttatctaca ttacgcattt ggaataccaa catgacgaat ccctccttct taattacaaa
     3481 tttttagcat ctaatttaac ttcaattcct attataca
//
LOCUS       DAEPUT010000165         3377 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.170, whole genome shotgun sequence.
ACCESSION   DAEPUT010000165 DAEPUT010000000
VERSION     DAEPUT010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3377
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.170"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..344)
                     /locus_tag="KRL22_003808"
     CDS             complement(<1..344)
                     /locus_tag="KRL22_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBH1274229.1"
                     /translation="MKTDVIINRDALAALKELPSESVHCCVTSPPYYALRDYGLDAQI
                     GQEDTPEQYIDRLTAVFGELYRVLRKDGTLWLNIADTYCGTGNKGGYADPKNPKGRTG
                     QRIARNSRVTGC"
     gene            complement(341..2770)
                     /locus_tag="KRL22_003809"
     CDS             complement(341..2770)
                     /locus_tag="KRL22_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1274230.1"
                     /translation="MSKGQTKKTREAAGNRRKLTRAEKKQIAEAIRKAKGDGKARTAQ
                     QTIPYLAMYPDGICKVTEKRYSKCVMFEDINYQLAQADDKTAIFENWCDFLNYFDASV
                     SVQLSFINQGTQREQAEKAISIPAQEDAFNSIRTEYSDMLKNQLSKGNNGLVKHKYIT
                     FTVEADNKAAAKSRLSRIETDVLNNFKVLGVTARPLSGYERLKVLHGVFHPEGEPFSF
                     SFDWLTPSGLSTKDFIAPSSFRFGEGRYFRMGKKIGAASFLEILAPELNDRMLADILD
                     LETGVIVNLHIRSIDQSEAIKTIKRKITDLDKMKIEEQKKAVRSGYDMDIIPSDLATF
                     GSEAKNLLQDLQSRNERMFLLTFLVVNMADTKRKLENDIFAAAGIAQKYNCRLTRLDY
                     QQEAGLLSSVPIGENLIPIQRGLTTSSTAIFIPFITQELFQTGQALYYGLNALSNNMI
                     LCDRKQLKNPNGLILGTPGSGKSFAAKREMTNAFLITDDDIIICDPEAEYFSLVQRLN
                     GQVIRLSPTGRGIDGKPQYVNPMDINLNYSEDDNPLALKSDFILSLCELVIGGKEGLQ
                     PVDKTVIDRAVRNVYRPFLADPDPAKMPILGDLYDELLRQPEPEAARIAAALELYVSG
                     SLNVFNHRTNVELSNRLVCFDIKQLGKQLKKLGMLIVQDQTWNRVTINRAEKKSTRYY
                     MDEFHLLLKEEQTAAYSVEIWKRFRKWGGIPTAITQNVKDLLASREVENIFENSDFVL
                     MLNQAQGDRTILAKQLNISPQQMKYVTHTEAGEGLIFYGNVVLPFVDRFPKDTELYRV
                     MTTKPEEVSSL"
     gene            complement(2718..3122)
                     /locus_tag="KRL22_003810"
     CDS             complement(2718..3122)
                     /locus_tag="KRL22_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBH1274231.1"
                     /translation="MAYVPVPKDLSKVKTKVAFNLTKRQIVCFAAALLIGLPLFFLLK
                     GSAGTNLAAMAMIVVMLPCFLLAMYEKHGQPLEVVVRNVIQTKFTRPKERPYRTENLY
                     AVLEKQRNLEKEVSAIVKRTNKKDAGSRRKQA"
     gene            complement(3144..>3377)
                     /locus_tag="KRL22_003811"
     CDS             complement(3144..>3377)
                     /locus_tag="KRL22_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274232.1"
                     /translation="NREWGQIGNNYLKGLFALGFQGFLIMICVGIYAVLVNDMIIADN
                     LHSAVFSLAAYTVILCFSLFKSGTLAKSIFNAH"
BASE COUNT          755 a          842 c          847 g          933 t
ORIGIN      
        1 ttgcagccgg taacgcggct gttccttgca atccgctgtc cggtgcgtcc ctttgggttt
       61 ttcgggtcag catagccgcc tttatttcct gtgccgcaat aggtgtctgc aatattcagc
      121 cataacgtac cgtcctttct aagcacccgg taaagctcgc caaaaacagc ggtcagcctg
      181 tcaatatact gttccggcgt gtcctcctgt ccgatttgtg cgtcaagccc atagtcccgt
      241 agcgcatagt acggcgggct tgtaacgcag caatggacgc tttcagaggg cagttctttt
      301 aaggcggcaa gcgcgtccct gttgataatc acatctgttt tcataggctg ctcacttcct
      361 ccggcttcgt cgtcattacc ctgtaaagct cggtatcttt cgggaagcgg tctacaaaag
      421 gcagcaccac atttccataa aagataagcc cctcgcccgc ttcggtgtgg gtaacgtatt
      481 tcatctgctg cggggaaata ttaagctgct ttgcaaggat agtacggtcg ccctgcgctt
      541 gattgagcat aaggacaaaa tcactgtttt caaagatatt ttccacctcg cggcttgcca
      601 aaaggtcttt gacgttctgc gtaatggctg ttgggatacc gccccattta cggaaacgct
      661 tccaaatctc cacgctgtaa gcggcggtct gttcctcttt taagagcaaa tgaaactcgt
      721 ccatatagta gcgggtggat ttcttttctg cccggtttat cgttaccctg ttccatgtct
      781 ggtcttgcac aatgagcata cctaactttt tgagctgctt cccaagctgc tttatatcaa
      841 agcagacaag gcggttagaa agttccacgt tggttctgtg gttgaatacg ttaaggctgc
      901 cggaaacata cagctccaat gccgccgcga tacgggcagc ttccggctcc ggctgtctta
      961 gcagctcgtc gtaaaggtcg cccaagatag gcatttttgc cgggtcgggg tctgcaagga
     1021 acgggcggta cacatttctt acagccctgt caatgacggt cttatcgaca ggctgcaagc
     1081 cctccttgcc gccaatgaca agctcgcaga gggaaaggat aaaatcactt ttcaacgcaa
     1141 gagggttgtc gtcctcgctg taattaaggt ttatatccat agggtttaca tactggggct
     1201 tgccgtcaat gcccctgccc gtaggggaaa gccgtatcac ttgcccgttt agacgctgca
     1261 caagggaaaa atactcggct tccgggtcgc agatgataat gtcgtcgtca gtaatgagga
     1321 aagcatttgt catttccctt ttggcggcga aactcttacc gcttcccggc gttcccaaga
     1381 taagcccgtt tgggtttttg agctgctttc tgtcgcagag tatcatgttg ttagaaaggg
     1441 cgttcaagcc atagtacagg gcttgccccg tctgaaataa ctcctgcgtg ataaagggaa
     1501 tgaaaatagc ggtgcttgat gtggtaagcc cccgctgtat cgggataagg ttttccccaa
     1561 tcggcacact ggataaaagc cccgcttcct gctgatagtc aaggcgtgta aggcggcagt
     1621 tgtatttctg tgcgataccc gccgccgcga aaatgtcatt ttccagtttc cgcttcgtgt
     1681 ctgccatgtt taccacaagg aacgtaagga gaaacattcg ctcgttgcgg ctctgtaagt
     1741 cctgcaacaa gttctttgct tcgctgccaa aggtggcaag gtcggacggg attatatcca
     1801 tgtcatagcc gcttctaacc gcttttttct gttcctcaat cttcatcttg tcaaggtctg
     1861 tgattttgcg cttaatggtc ttgattgctt ccgactggtc gatactgcgg atatgcaagt
     1921 tgacgattac gcccgtttcc aagtccagta tgtcggcaag catacggtcg ttgagttccg
     1981 gcgcaaggat ttcaaggaag ctcgccgcgc cgattttctt ccccatgcgg aaatatctgc
     2041 cctcgccaaa acggaaagag gacggggcga taaaatcctt tgtagacagc cccgacgggg
     2101 taagccagtc aaaggaaaag gagaacggct cgccctccgg gtgaaatacc ccatgcagca
     2161 cctttaagcg ttcatagccg gataaggggc gggcagttac gccaagcacc ttgaaattgt
     2221 taagcacgtc ggtttcgata cgggaaagcc ttgactttgc agccgccttg ttatcggctt
     2281 caacggtaaa ggtaatgtat ttgtgcttca caagcccgtt gttgccttta ctaagctgat
     2341 ttttcagcat atccgaatac tcggtgcgga tagaattgaa agcgtcctcc tgcgcgggga
     2401 tagagattgc tttttctgcc tgttcccgct gcgtcccttg attgatgaaa gaaagctgca
     2461 cgcttacgct cgcgtcaaag tagttgagga aatcgcacca gttttcaaaa atggcggtct
     2521 tatcgtcagc ctgtgcaagc tgataattga tgtcctcgaa catgacgcac tttgaatatc
     2581 ttttttccgt aaccttgcag ataccgtccg ggtacatggc aaggtaggga atggtctgct
     2641 gtgcggtgcg ggctttgccg tcgccttttg cctttcggat agcttcggca atctgtttct
     2701 tttcggcgcg ggtcagctta cgcctgtttc ctgcggcttc ccgcgtcttt tttgtttgtc
     2761 cttttgacaa tcgctgatac ctccttttct aagtttcgct gcttttccaa gacagcgtat
     2821 aggttttcgg ttctgtaagg tcgctccttt gggcgggtaa actttgtctg aatgacgttt
     2881 cttaccacca cttcaagggg ctgtccatgc ttttcataca tggcaagcag gaagcagggg
     2941 agcatgacga caatcatcgc catagccgca aggtttgtcc ctgcgctgcc tttgagcaaa
     3001 aaaaacagcg gcagtccgat taagagagcc gccgcaaaac aaacgatttg ccgctttgtc
     3061 agattgaaag cgacttttgt tttgactttg gataggtctt ttggtacagg tacatacgcc
     3121 aagaaaaaac ctcctttctg cccttagtgg gcgttgaata tggattttgc cagtgtgccg
     3181 gatttgaaca gggaaaaaca gaggataact gtataggcgg caagggaaaa taccgcgctg
     3241 tgcagattgt ctgcgattat catgtcgttt accagtacgg cgtaaatacc gacacatatc
     3301 ataatgagga agccttgaaa accaagagcg aacagccctt ttaggtagtt gttcccaatc
     3361 tgtccccatt ctctgtt
//
LOCUS       DAEPUT010000166         3362 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.171, whole genome shotgun sequence.
ACCESSION   DAEPUT010000166 DAEPUT010000000
VERSION     DAEPUT010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3362
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.171"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..285
                     /locus_tag="KRL22_003812"
     CDS             <1..285
                     /locus_tag="KRL22_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HBH1274233.1"
                     /translation="LEDYNRASGVIKLENKMIKLTPTENRLLNYFIENAEKTLTIKEI
                     YEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIREVGYYFNKI"
     gene            733..1017
                     /locus_tag="KRL22_003813"
     CDS             733..1017
                     /locus_tag="KRL22_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274234.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     gene            complement(1174..1347)
                     /locus_tag="KRL22_003814"
     CDS             complement(1174..1347)
                     /locus_tag="KRL22_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase"
                     /protein_id="HBH1274235.1"
                     /translation="MKRKLSTYFKGYILGLCIAFLLFTFILKKLIIENIIGIIIGTGI
                     AFLLIYLFNKKRK"
     gene            complement(1788..2003)
                     /locus_tag="KRL22_003815"
     CDS             complement(1788..2003)
                     /locus_tag="KRL22_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274236.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(2014..2481)
                     /locus_tag="KRL22_003816"
     CDS             complement(2014..2481)
                     /locus_tag="KRL22_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH1274237.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMIISFIFALMCFVIAETFDKAIKIKEDNDLTI"
BASE COUNT         1400 a          301 c          422 g         1239 t
ORIGIN      
        1 ctagaagatt ataatagagc tagtggagta ataaagttag aaaataaaat gataaagtta
       61 actccaacag aaaatagatt attaaattac tttatagaga atgctgaaaa gactctaact
      121 attaaggaga tatatgaaca tgtatggatg aatgagtatt tagatgataa ttatagtgta
      181 gtggttgctg tgagtggatt aagaaagaaa atagagaaag attataaaaa tcctcaaaaa
      241 attataacga taagagaagt agggtattac tttaacaaga tataaagctt tataaacaga
      301 atgaatgata aggcatagat aatatgttag tatattataa gagtttttgt tctaacgata
      361 tatttgtaaa attagattta atttacttaa ttaaattata gcagtagaat aaatataaaa
      421 aatgtctgaa atattataga catcagtaaa atatataaaa ctataatata agtcgtaata
      481 ataaaacaaa tgaatattaa ttaataaaaa gatagtagct atttttatat agctattatt
      541 tttttattgt tgtggatgaa aatatactta tattttacta atatacattt aaaaattata
      601 atttaaagca ttaaaaaata aatttgtatt ttgttttata taaagtaatt tgaagaatat
      661 ggaaaaactt gattagtaca ttattaatta gggtataaaa tggtgtaaat agaatgataa
      721 ggggtggatg aaatgcttgt atataataaa agtttttatc ctaatgacat atttccaaga
      781 ttagattttt caaaaataaa aaaacagtta aaattgatag ataatgacct gtcagatttt
      841 ggaagcatat gtataataga aaaagaacat tatacaataa gtgtaaacag tataggtgaa
      901 ataaatgtgt attatgattt agagtacgaa aataaggtgt atagaatagt ttatgagatt
      961 gaaaagttat ttaaatctca agttggaagg tttagcatat ctacatacag aaattgataa
     1021 ttaaaaaagt agaaattaaa aaacttaata ctaaagatat agataaatat atgaggtaac
     1081 agctagagag agttgttacc ctttttaaat actaagtata tattattctt attaattttt
     1141 tgtaaattca ctaaaagacc tttttataga atattatttt ctttttttat taaataggta
     1201 aatcagtaaa aatgcaattc cagttccaat tattattcca atgatatttt ctataattaa
     1261 tttttttaat ataaaagtaa ataataaaaa tgctatacat aaacctaaaa tatatccttt
     1321 aaaataggtt gaaagttttc ttttcatata atcaccaact tgtatcagat ttagtttact
     1381 taattagagt ataacagtgt tgtaacttca aagagtatct aaaagattac aaatgttaga
     1441 taaaatcatc aataatgtaa tttataacac gtagctataa actatgcaat aatataaatg
     1501 gaggtataag taaatgaaaa agttccatgt tttgctaaca gtttaaataa atattaggta
     1561 gaaaagaatg tatataggaa tctgtggtaa aattatcaat ttaaaagtat tatttagtgt
     1621 gatacagttc ttataggtaa tggataacaa atagataaag gaacagtttc tttcttagaa
     1681 catattttgt tatgacttta aacaaagtta atattaatgt caataatata gtaaaagaat
     1741 aaaaatcata tagtataata aaaaagagtg tttctaaaca ctctttttta atcattttca
     1801 tcttctacat attcaagtat atcacctggc tgacagtcta aagctttgca aatttcgttt
     1861 agagtggtaa atctaatagc ttttgctttt ccagttttta aaattgataa atttgcattt
     1921 gtaatatcta ttttttctgc caaatcttta agtgatattt tcctttttgc catcattaca
     1981 tctaggttaa ctactattgc cataacatca cctctatatc gttaaatcat tatcttcttt
     2041 tatttttata gctttatcaa atgtttctgc aattacaaag cacattagtg caaatataaa
     2101 agagataatc ataagtggtg agataccgcc actatcagtt ccaaaaattc ttatattatt
     2161 agtatttaaa ttataaccat tgatacattc aattatagtg tttatcaata aacaaaatcc
     2221 cattacctta aaccttttta cattttcaag tacgaatggg gaatacttag tactattaat
     2281 tataaatatc aagaataaga tgactataaa gtagtcagaa aaatatagta ttcttgcaat
     2341 taaagcgatt actttgtcag aactaaaatc atataaaaac ataggtatca tacataagaa
     2401 tattatacca gcaactccta aaagtgataa tagaaaatat agaaatactg ataatatatt
     2461 actaaaaaat tttgtaatca taaaatatca tctcctttat ataaagtata ttattgatta
     2521 taatatacaa tttattgaat ttcaataata aattattgat ataatatata aaaccattgt
     2581 aatatacact aaaaataaga atgtataagg tggtaaattt atataaaaaa gaatatgagt
     2641 tgtaaaatat taaataatat tgtactaatt ggaataattt taactttatt atagattatt
     2701 ttaataccat tagtactgat ggtgtatttt aaaattggta taagcattac aaatacgaat
     2761 atgccaactg taatatgtaa tataagtagc tatatacata tgtgctgtcc catatattgt
     2821 atcattgttt atattaaaaa gattatgtaa attggtatca atcaataaat cattttcaga
     2881 agaaatacct aaaaacttaa aaaataccta tatgtgtatt tagttagatt tgagattttt
     2941 acatttaatt ttatagtgac aatattatat tatttttatg atgtctattt atatgcaatt
     3001 actataatat cagaacttat agtatcattt gtttcattat caataaggtt ttttacttta
     3061 gttttgtcaa ttttattaaa aaaagttatt gatataaaag ataagaagga taaaactata
     3121 tgacggattt caaacataag agtggatatt tatataatag atattttata gttaatttta
     3181 ttagatttta tttaatactg taatattaat atcacaatat attaatagtg tattaaagat
     3241 tgaattttgt agataactat aatttattga gagtgataaa taaaaattat ataatattac
     3301 agaagaaaga gagggagaca atattatatc cctctttttt ctataataac taattattaa
     3361 aa
//
LOCUS       DAEPUT010000167         3347 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.172, whole genome shotgun sequence.
ACCESSION   DAEPUT010000167 DAEPUT010000000
VERSION     DAEPUT010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3347
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.172"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(52..417)
                     /locus_tag="KRL22_003817"
                     /pseudo
     CDS             complement(52..417)
                     /locus_tag="KRL22_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(438..1517)
                     /locus_tag="KRL22_003818"
     CDS             complement(438..1517)
                     /locus_tag="KRL22_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HBH1274238.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYGASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELRGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            complement(1571..2860)
                     /locus_tag="KRL22_003819"
     CDS             complement(1571..2860)
                     /locus_tag="KRL22_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH1274239.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     misc_binding    complement(3023..3234)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1103 a          673 c          368 g         1203 t
ORIGIN      
        1 tttagctact aactcatgac taaagtcacg agtgtgcgta gctatttttt aatcaaactc
       61 atatccacca gataccaata ttgaatctaa ttctattttt tctcttaagt cttctggcca
      121 atctataaat ggaagaatgg cagtagtggc tggctttcct attcttatca tagccacatt
      181 attaagtctt tttctttcta caatagcatt tgtacaatga gttgtaccaa gcatagcata
      241 ttttattaat gaatggtcaa tcttactttc atctataact ttttttaagg cattgtaaac
      301 accagtttca acatcttttg tagttgccac cttaactgaa tgaattactt ttaattcccc
      361 atccagtata caagcatctg tatttgttcc tccaacgtca attcctacac gatacatcaa
      421 aatttcctcc taaactttta ttttccttgt aattcttcta ctgttttata ttccacatca
      481 tatccaaagt atccaggtcc aactgtctca attccttttt ctgttctcca cttttcatta
      541 caaggaaaag ctactaccat aacacgagag ccatatttta ttctctctgt agttattgga
      601 aatccagttt ctaaatctaa tactgctatt aaatctggtg taatacaaag tggtgtatca
      661 ccttttttgg caattaaatt ctcattttgg aataatatag aatactctcc atcatactca
      721 ttaatcccag caaaaaaggc atgtcctcta gtaaatccac ctttcaactc tctcttaata
      781 tcaattactt ttccttcaaa taacttgtat ccacgcaatt cttttagtat attctcaaca
      841 gcaccttttg aatcagattt attttcaagt aaaaaccctc ctatagtttc agctattgta
      901 agagtattac ctatagcagc ttttttaact tgagctccac ttaaattata gtcactaata
      961 gaagaacttc ctcccatttc tacagttaaa gttctagcta atctttctga ccaaattcca
     1021 tccacaggat aaaggatggc agaattacct ttttcatcag acattacggc aggagatgcc
     1081 ccatatcctt caagataaaa agttaccatt tgagcttcag ggaacgctct acccatagaa
     1141 tctgcatcta agataggaag tcctttttta gcagcaactg ctataggcat aagtgagttt
     1201 atccctccta tttctatagg aattataaca tccacttttc tatttaataa tttctccatt
     1261 atttctaaag gggtagttaa ctctacttct gaaagtaatt tttctattgt aattacagga
     1321 gaacccatac cagatactgg aactaccaaa gcatcatcat caagttcatc taaacttatt
     1381 acttttacag gaccatactt tttaatggct tgttttgcaa ccaatttacc tacatatggg
     1441 tcacctccac ctccagttcc aagcactgct gcaccaactg ctattttatc tacactttct
     1501 tctgttaaaa atctcatgtt actttctcct catatttcta atttatttta tactttataa
     1561 acaaatttct ttatactgct ttgtctattt cttgcttatt ttttgttgaa caaagcactt
     1621 ttccaataat agattgtact acaaaccctg ctataaaacc atctaaaggt gctatagtag
     1681 taagagttat aaatccatat gttgaaaggt aagttattaa tataccaatt atccaagaca
     1741 ctattgaacg tttaactatt ggtttatata atactccttt atcaaagcct ttaagttctt
     1801 gctttactat gtaatattct gctgtatata caccaccaac aggtgcaatt acaattccaa
     1861 gtaaatttaa aaatcctata aaaccttcat atattccaaa tacagccaat aatgttgcta
     1921 taataccaag gactatagtt aatactttct caggagcctt cttaagtaca agagctatac
     1981 ttaatgatgc tgaatataca ttacttgtat ttgtagtcca ttgtgctaat gtaagtacta
     2041 ttatacctgg tatagcaatt cctaatgtaa taaaaattct cataatatct gaagttccca
     2101 tacattttac taatactatc gaaactatta tcataaaagc atttccaaat tgtattccca
     2161 aaaagcttga aagagcacag tctcttctac ttttagccca acgacttata tcaggagata
     2221 caattgcacc aactattatt atactcattg acagagaaac tccacctgca aatgtcatag
     2281 tagatttcat attatcatca actgaaattc catttgctct aaaagctaag aatatagtta
     2341 gcatcataag aactaataaa aatggtactg aatacacact caacttctcc attgccttat
     2401 atccataaat tgcagtactc atcatcaaga gaccacctat taggcttaaa atctgcatac
     2461 ttacatctaa attaaatata tcttttatta ttatctgtgc attttgagca aagaaaccta
     2521 cttgaactcc aaaccaacct aatagagaaa cccctataac tagagaaaat atttttgctc
     2581 cagcttctcc aaatacatac tttgttatca tagatgtaga taaacttgta gatgagccaa
     2641 ccaaagagca tgtagtatac aaaattgcag aaaaaaatga accaacaatt actgacaata
     2701 ttgcttgttt cattggcata ctctgtgcca actcagcgcc taaaataaca gatgataaat
     2761 ccacacctat tgctactaaa actgaaaaca tagctaccca accacgtttt tgattctctg
     2821 gaatctgttc cagagcatag ttaatttttt cttcttccat tttcatccct ccatttaaat
     2881 cgtaaaacta ctgaccttag catattttac aattttctaa tttataaatt tattaactat
     2941 catattttta taattttcat ttaatatata gttttaaatt ttctgaaata agtttataat
     3001 aaaaaacgcc tcttggaaaa atccaagaga cgaatataaa tccgtgttac cactcttatt
     3061 agtaaaaatt aattttactc actcattttc ttaaggcgaa ttaaaccact attctaacat
     3121 aattacaata gtattctcca aagtcctttt cacataaatt ccaatattag ttctcagcca
     3181 aatctaactc tctgtaaaat tcctttatgc tactttcttc ttctacgaat atataatatt
     3241 gatttgtagt taatttatga tttatatcat aatatatatg caatattttg tcaacttaaa
     3301 aagtcaatta cttgcatttt ttagttttat atgtaaattt tcatact
//
LOCUS       DAEPUT010000168         3309 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.173, whole genome shotgun sequence.
ACCESSION   DAEPUT010000168 DAEPUT010000000
VERSION     DAEPUT010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3309
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.173"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(56..628)
                     /locus_tag="KRL22_003820"
     CDS             complement(56..628)
                     /locus_tag="KRL22_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1274240.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(657..923)
                     /locus_tag="KRL22_003821"
     CDS             complement(657..923)
                     /locus_tag="KRL22_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH1274241.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            complement(923..1132)
                     /locus_tag="KRL22_003822"
     CDS             complement(923..1132)
                     /locus_tag="KRL22_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH1274242.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            1401..2261
                     /locus_tag="KRL22_003823"
     CDS             1401..2261
                     /locus_tag="KRL22_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBH1274243.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2309..>3309
                     /locus_tag="KRL22_003824"
     CDS             2309..>3309
                     /locus_tag="KRL22_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH1274244.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEMMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEYEYKYEIKNIIKMFDEDLDNEKIYINKC"
BASE COUNT         1280 a          378 c          540 g         1111 t
ORIGIN      
        1 aacacaacag taaattataa attatcaaat aataatagtt atacaaataa aaattttaga
       61 acattttttg agattcttct aactcgtaag catccattaa agcttcacca aatctttgat
      121 agtgaattat ttctctttga cccaagaatt ttaatacatc tataacatca acgtcatctg
      181 ttaggtttat aagttgataa taagttgcaa gtgctttttg ttcagctgcc atatcctcat
      241 gtaaatcggt tacgggattt gacataactg ctataggtct tacatcaaat ggaacaccat
      301 ttgaatctgt tggataaatt ccatatccat tttgagcata gtttgaacca agacctgcag
      361 cttttaactc ttctgggctt gcatcagaag ttaactgata aaccatagta catataagct
      421 caacgtgagc tagttcttct gtaccaatat ctgttaaaag tgcacgcata ttaccagtag
      481 gcattgtata tctttggctt aaatatctta aagatgcagc aagttctcca tttggcccac
      541 caaattgagt tataagaaat ttagccattc tagggtcaca agtttttata ttaactgggt
      601 gttgtatagt tttctgatat atccacatga attttcaatc ctccaatact tgatgtctaa
      661 taattaaatt ctctgtccca aggccaaggt tggtcagccc attgccaagg gcatctactt
      721 ggagcatacc caaagttagt taaaggaccg tatttatttt cgtaagcata tctagcttgc
      781 gcaaattgat tacataatga attataagtg ttgatagcat ttttatcatc agggtgattg
      841 tctaaatata agttcatatc aacacatgca aaagatgttt cctgaacttt tctcataagt
      901 tcagctctag atgagtcttt cattatcttc tacctcctct atattttttt ggcttagcat
      961 ataattcttt gttgtacatt tcagactcta gtaagtttag ttctggaaat atagttccaa
     1021 attttaatgc atcagaaagg cagtacattt ctgtgaaaat ttgattatta atgtatggtc
     1081 tagccaaaga tggaccacaa ttttttttga tatctctagt cttattttcc aagatgaaaa
     1141 cctccttgtt gtaaatagat aggtaactct atctagtgta taatattcaa tcatttaaaa
     1201 atcgttacta ataataaaat attaaatgag aaaaataaaa aagataataa aagaaagagg
     1261 ttatttatgt tattataagt ttatgtgtta ttgtaaacta taaattattt agtaaaatta
     1321 aagtaaaaat tatagtattt tgtggatgaa ggtagacttt tttgtaaaat attattaaca
     1381 taaatatacg aggtgattag atgagtgaac tatcaggaaa aggctgtgaa attatagttc
     1441 cttttgagga aagacttcca gtaagagata tagaaaaaag tataataaaa aaatatagaa
     1501 aaaatttatg gtctaagttt atgaaggcaa taagagatta taaattggtt gaagaaggtg
     1561 ataagatagc tgtagcgatt tctggtggaa aagacagtat tcttatggct aaaatgtttc
     1621 aagagttaaa aaaacatgga caagttaatt ttgatgttga atttattgct atggaccctg
     1681 gatatcatgc aaatataaga caattactta tagataattg tgagtatcta aatataccaa
     1741 tacatttatt tgattcaagg atatttgaga tagcagatga aatagcaaaa gattatccat
     1801 gctatatgtg tgcaagaatg aggagaggag cattatattc aaaggcagaa gaattagggt
     1861 gtaacaaact tgcattaggt catcattatg acgatgtaat agagacaaca atgcttaact
     1921 tattgtgtgc tggaaatttt aaaacaatgc ttcctaaact taattctact aattttgaag
     1981 gtataaaaat tataagacca ctttattata taagagaaga acatattata agatttattc
     2041 aaaatagtgg tatatggcca ttaaattgtg catgtatggt tgctgctaaa aaaacaggta
     2101 ataaaagata tgagataaaa gacttaataa agagtttaga atcaaatttt aaaaatgtag
     2161 aaaaatctat atttaaggcg gcagaaaatg taaatcttga ttcagtactt ggttggcaaa
     2221 aagatgggga gaaacattct ttcttagaaa attttgaata aaaatagtta aaaagaatca
     2281 ctataaacaa ttggaaaggg tgtttatatt gaaaagagta tatatagatt ttgaaatgaa
     2341 tatgccaaat tctaaatcaa aaagagcagt atttaattct gatataattg caatcggagc
     2401 agttatgtat gatgaaaaaa caaaaaatat tgataaattt aaatctttaa taagaccagt
     2461 aagtaatgag gagttgtatc ctcatataca agaattaaca catatatctt ctgaagaatt
     2521 gaagagtgca ccaagttatg aagaggtcat gagaaagttt aaaaaatggc ttggcatatt
     2581 ttctgatatt aaaggaatat atacttttgg taatttggat ttgacatgtt tcaataacac
     2641 agatatgaga agtgctaaaa aaaataacca tccaaggttt gtaaataaca ttagagattt
     2701 atttgtagat ataaaagaaa aatatataaa ttgtggtatg agatgtatga actatatatc
     2761 attgaaaaat ttacttgaat ttgttaactt agagtttagt ggagatgccc atgacccatt
     2821 aaatgatgca tataatttat ttattttgga tgaggcaatc acaaataatg tagacataca
     2881 aaatctttta ataatacgtg acataataag accaccattt aacgatataa attctaattt
     2941 agataattgt tttaacaaat ttaaggagtc attatataaa aaagaaggaa attataatat
     3001 tgtagatttt tctgttgaaa taataaaaac tgttagaatg tacttattaa caatcataga
     3061 tgtaaatata caaaatttag aaatgatgaa agatataagt aaaaaaatgg atactataga
     3121 taaattgaaa gatatagagg aaggctattt ttatttatta gaagatgtgt acttcgacat
     3181 gaaagatgta ctagaagatt taatgcttta tagaatgaat gaatatgagt acaagtatga
     3241 gataaaaaat ataataaaaa tgtttgatga agatttagat aatgaaaaaa tatatataaa
     3301 taaatgtaa
//
LOCUS       DAEPUT010000169         3274 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.174, whole genome shotgun sequence.
ACCESSION   DAEPUT010000169 DAEPUT010000000
VERSION     DAEPUT010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3274
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.174"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            89..844
                     /locus_tag="KRL22_003825"
     CDS             89..844
                     /locus_tag="KRL22_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1274245.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKEDLTVEEILEKFEYAV"
     gene            941..1978
                     /locus_tag="KRL22_003826"
     CDS             941..1978
                     /locus_tag="KRL22_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1274246.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGISQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNSTKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSAK"
     gene            2787..>3274
                     /locus_tag="KRL22_003827"
     CDS             2787..>3274
                     /locus_tag="KRL22_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1274247.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPTVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKS"
BASE COUNT         1243 a          429 c          494 g         1108 t
ORIGIN      
        1 ctagctactg gtaacttaaa tatttcacta aaaaaaaaca aatacaaagc tagtaccaaa
       61 aataaatcag aaaaaagagg tgttgtagat gttacaaatt aaaaatcttt caaagagttt
      121 ccctaatcca tatggtgaac ctaatactat ctttgaaaat ttatcaatcg atatagaaga
      181 tggtgaattt gtaagtatca taggtagtaa tggaactggt aaatctactt tattaaatat
      241 aatatctggg cttataaaag aatcttctgg tcaaattact ttagatagta ctactataac
      301 aaatttagct gagtataaaa gaactcaaat agtaagtaga gtttttcaag acccaagcct
      361 tggaacttgt ccttctatga cggttagaga aaatttatct ctagcactta ataaagggaa
      421 attattgaac ttaaaaaaat gtcttcgtca taaaacgaat gacttggaac acttacttga
      481 aggaatttct ttggatttaa aaaaatattt agatattaaa gtacaatatc tttcaggagg
      541 tcaaagacaa tcactatcac taattatgtc tagcttagca agtcctaagg tcttattact
      601 agacgaacat acagcagcac ttgacccaaa aacatcaaat gaagtaatag agttaacaga
      661 taaaatcgta agagaaaaaa atataactac acttatggtt actcacaact tgaaacacgc
      721 tcttcaatat ggagataggt tgataatgct tcataagggt gaagttgtat tagatgtaaa
      781 agataaagaa aaagaagatt taacagttga agaaatctta gaaaaatttg aatatgcagt
      841 ataagaaatt aaaatcttag ttttaatcag aaatatttat aatctatcat atgaatatat
      901 gaacaaatat aattaataaa ttttaaggga ggaaaataaa atgataaaaa gtaaaaaaat
      961 attaagttta attatagcag gagtacttgg tgtatcaatg cttactggat gttctcaaaa
     1021 tgatggctcc aatgcttcaa atgaaaataa agaaacagat agcaaaaaac aaaaaaatat
     1081 aggtattagt caattagtgg aacatccatc tctggataaa gcaaagaaag gattcatcaa
     1141 agcactcgaa gataaaggct ataaagatgg agataatata aaaatagatt tccaaaatgc
     1201 acaaaatgat atgcctacta cacaaagtat tgctagtaag tttgtatccg acaaaaaaga
     1261 tttgatatat gctatatcta ctccatctgc acaagcagct tataattcta ctaaagatat
     1321 tccgataata atgactgctg ttacagaccc tgtagaagct ggacttgtta aatctcttga
     1381 aaaaccaggt ggaaatgttt ctggtacatc tgattatctt tcaattgata aaacattaga
     1441 attggttaaa acattgactc caaaagcaaa gaaaataggg gttatataca atactagtga
     1501 agttaattca aaaatccaag ttgattctct acatgattat gctaagaaaa ataattatga
     1561 agtagttgaa aaaggaatca gctcttcaag tgaagttaac caagctattt ctagtttagt
     1621 tggcaaaata gatgttttat atgtccctac tgacaattta atagtttctt ctatgccaat
     1681 agtttctaaa gttgctaatg aaaacaagat tcctataata gcctctgaag aaggttctgt
     1741 atcttctggt gctttagctt gttgtggaat agattatgaa aaactaggtt ataaggctgg
     1801 agaacttgct attgaagtat tagaaggaaa atctgttggc gatataccag ttactacatt
     1861 agatgaaact gaaataataa ttaacgaaga tacactaaaa gcacttgaca tgcaaaagtt
     1921 atcagcagat aatataaagt atataaagtc agatgaaaat gcaaaatctg caaaataaaa
     1981 cctattaatt tcaaaaaata ggtaatatga agtaggtaat atgaaaactt tatataataa
     2041 gtactcttat ccaccctaac cctttgaaaa ttgtgcttat tgtagcaatt tgaatattgc
     2101 atataaagtt attcattttc cataaaagtc gtctatattg acgactgatt atgaaagtta
     2161 tataactttc taatcactac ttgagctgtc caaaagaatt ttaatattct ccagacagct
     2221 tttttttatg atatttgatt gatatacatg tctagttatt ccatatttag taaatatttt
     2281 gataaaattt ccacattcac ttataactta ggataacgtt tttttcaaac aatacattaa
     2341 tttaaaagta ttctgagtat acattattta gtattttaat taaatttagc agttgacttt
     2401 tattattgta taatttataa tttataacaa gtcaagaata catataattt tctgactaat
     2461 taaaatatta aaagggagag ataattatga atactttatt aaacaataga aaatattatt
     2521 attattatag ccactatttt tagggtttgt acctacgttt taacatagat acagacccct
     2581 taagactact aaaattttgg gattgtatct atgttggcta tattgtttat aaagttttca
     2641 tttaactata taagagccac atagattaaa ctatgtggct tattcgtgtt tttaccacat
     2701 agttttgtac actatgtggt ttttttatac acaaaattag caaataatta aaattataaa
     2761 aatattttca aaggagtgtt ttatttatgt caggtattat atctgtaatg acgcaaagtt
     2821 taattttatc gattatggca ctgggggttt atataactta caaaatctta gattttccag
     2881 atatgtctgc tgatggtagc tacacaatgg gtgcttctat tgtagcattt tctcttacta
     2941 atggtatttc tcctgtagta gcaactttaa tggctatctt atgtggttgt actgctggtc
     3001 ttgttacagg gattcttcac attaagttta agatatctaa cttactttct ggtattttag
     3061 ttatgggaat gctatactct atcaatttaa gaataatggg aaaatcaaat attcctctat
     3121 ttagctttaa acacttattc aatggggaaa tatctcctac agttttagcc ttagcttttg
     3181 tattcatctg taaagtcctt ttagatttat tcctaaaaac aggtcttgga tacactttaa
     3241 aaggtgttgg tgataactct caaatgatta aatc
//
LOCUS       DAEPUT010000170         3127 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.175, whole genome shotgun sequence.
ACCESSION   DAEPUT010000170 DAEPUT010000000
VERSION     DAEPUT010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3127
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.175"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            224..1117
                     /locus_tag="KRL22_003828"
     CDS             224..1117
                     /locus_tag="KRL22_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH1274248.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
     gene            1560..2051
                     /locus_tag="KRL22_003829"
     CDS             1560..2051
                     /locus_tag="KRL22_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274249.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYTGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSF
                     KIE"
     gene            2079..3026
                     /locus_tag="KRL22_003830"
     CDS             2079..3026
                     /locus_tag="KRL22_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274250.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGCIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
BASE COUNT         1370 a          265 c          431 g         1061 t
ORIGIN      
        1 agatttaata atatttttat tatataaata gttaaaataa gcttatctaa ttatttattt
       61 taactgtttt gtgtgataga aaactatata ttataacaat agtagtgctt ttaattaaat
      121 atatttcata aatcttcata aaatcttcaa aatttcgtaa agaatatgtc acaaaagtaa
      181 ggtatattat attcagcaga tagtataagg gaggacaata tttatgaaga ataaaaaatt
      241 cattgttata atactgataa tatcaatttt aataggtgta ttagtgaagg aatattcatc
      301 tagagagata aaaaaggatg atataaatgt cagtaagtat ataaaatatg ctgatttagc
      361 aagtaaaaat aatgcacaag ttaactggaa gtatgtagct tccattgttg ctgtgttaaa
      421 taaaaataac ttaaaaaacg ttaaggattc acagatacaa gaagtatcag atttatttgt
      481 taagaatttt tctaaaaata ataaaataaa taagttaagt gatattttgg atgagttaga
      541 atttagtaat agacaaaaaa gattggttga taattatata gacaatctta aggattatgg
      601 tataaaacca gaaagattga agtctgatac aaaatatatg aagtttattg atgaaattaa
      661 aacagaagca atacaaaatt ataaggatta taaaatactt ccatctataa ctattgcaca
      721 agctataata gaatctagct ggggtaagtc aactttggca aaacaatata acaatctatt
      781 tggtataaag gctgacgctt attggaaagg taagtcagtg actttagaaa caaaagaaca
      841 tttagataca attatagatg ataaatttag aatatatgat gataaaaatg aatctataaa
      901 agaccatgca aaatttttag ccacaaataa aaggtataaa aacaatggtg tatttgatgc
      961 aaaaacgtat atatatcaag ctaaagcatt agaaaaggca ggttatagta ctgcgaagga
     1021 tgaaaatggc aatagtatat atgcagctcg tctaatagaa ttaattcaac agtataatct
     1081 tcaattaata gacagtgaaa ttcaaagtga aatgtaactt tgattaaatt tttattgata
     1141 aggctatgat ttttaaaatc atagccttat tttgacatgt ttttactttt aattattaaa
     1201 tcgatatcat tatctttcaa aatttacttt atactgtaaa ttaaattatt taagttaaaa
     1261 cttggaatta tttataaaag gattatttac tttatctaaa ttctgcactc aaagaacatc
     1321 ttttccctta agactgaccg ttagtctata aaaattataa ttacttataa aaaagtgaat
     1381 agagagatat atatataatt ttcagaaaga cttttacttg taaattgaaa ttaatgaagt
     1441 aaaaaaggat tctttattaa aagtaaataa caactagata gtgaataata aaaaatggta
     1501 atttgaaata atttttatga atagtattaa tatatagata cagggagatt gatgcgatta
     1561 tgtatgaaaa taataaggta atatacaacc ttgaaagatg tgaaaaacta gaaaagactc
     1621 tttatttatc tcaatttaat acatataaaa attttaaatt agcttctaaa aaaactgtaa
     1681 taaattcatt agagacatat gtttacaata tgaatattaa caatataagt cttgttgata
     1741 ctatagaatg tatatcatta gaagatgaac aacttacagg aaagaagttg attttagttg
     1801 gtgatataga tattgatgca atattagatt atacaggcaa taaaagaaat agaaattcta
     1861 gtaaaaaaaa tacatttaaa ttaaaaatac cctttagtac atttatacaa atgcctagaa
     1921 agatagaaaa taaagataaa attaatttaa agtatcttat acaagatatt acttcatcta
     1981 ttttagatga taatttattt attagtgtta ctgcaattat aagttatgaa aatagtttca
     2041 agatagagta atctttaaat tatagaaagg tggatgcaat gagaataacg aaaactactt
     2101 ttaatgatgt attttcaaat gatgcaaatg gaagtattat aaaagtagaa aaatatgttg
     2161 ataaaaaatg tgcatctgta tttgagattt tgacctacac tattattgtt acaaatacaa
     2221 gtaggtacaa aactggaaat atatttttca aagattatat ttctaaatat atagagttta
     2281 taaataatac tgtaaaagtt aatggcatta taaaacgtgg attagaccca cagcaaggtt
     2341 tttacatagg gagaatagat gcaagttgta aaaaaataat atcttttaag agtgtagttt
     2401 taccaaattc tgcacatagg attataaaga atagtgctaa tatatactat tattataagt
     2461 gtaatctaga taaattccca acaagaatat caatagaaag taatagagtt tatactaatg
     2521 taaataaaat tgtattcaaa caattgaata taagtaatac tttaaaagct cctaaaaatc
     2581 taagagatat attaaaagta aatgtaaata gtaaaatatt tgatgttaaa cctatgaaaa
     2641 atcttataaa caaaggtagt aatttgaaat tatgtaactt gatagttttt gggtgtatag
     2701 aagttgaaat agactatagt tgtaaaaata ggagtaattt taaaacagta aataagtcta
     2761 atgacattaa aaaagataag tattataaaa atgatataca aaataacaat gaaaatataa
     2821 acgattgtaa aaagcaaata agttttggtg ataataaggt aaaaaaaata acaaaaactt
     2881 ttggattttc ttgtttcatt tgttctccag ttggaattat ttatgaagat atgaaaaata
     2941 taaatataaa aattgaacat acatcaataa atgaattaaa tccagaagaa ttatttgtaa
     3001 atacatcact tttattgtat tattaagtat tttaaagcta aaacttaaac ttattaaaat
     3061 agcatttggt taaaggaaaa tagatattga tatatttatc atatatataa atgattaatt
     3121 aaacaat
//
LOCUS       DAEPUT010000171         3006 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.176, whole genome shotgun sequence.
ACCESSION   DAEPUT010000171 DAEPUT010000000
VERSION     DAEPUT010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3006
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.176"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            461..2271
                     /locus_tag="KRL22_003831"
                     /pseudo
     CDS             461..2271
                     /locus_tag="KRL22_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
     gene            complement(2359..2940)
                     /locus_tag="KRL22_003832"
     CDS             complement(2359..2940)
                     /locus_tag="KRL22_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274251.1"
                     /translation="MLYLLKINQFEKSYDIGIFKNEQSIYKFIEKIPFVKKDNSNFNY
                     TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
BASE COUNT         1143 a          307 c          414 g         1142 t
ORIGIN      
        1 ttattgcaca aaaatagata taatttaagt aatataccaa aaaaaaggaa tatatttaca
       61 taatatgata aaataaattc aaagagttaa attgtaggta aatagtattt taattattta
      121 ttaaaatata gattatgtat atgccaaatt taaaaagaga cataaagaca ttatacaaat
      181 atattattgg ggtgatattt tgtaagaaaa gaagtgatgc agtaaattaa ttgagtaatt
      241 taaaaatgat ttaatgataa tgttgatgaa tgtttaaaaa gaaattttag aaaaacgtat
      301 attgctgttt gtgttggagg tgatgaattt gtagaattta tagggtataa atgattaaac
      361 tatttaagat aaatacatat cactgtaaaa tattgataat cattttttat aagagattga
      421 ttatttgcaa attatatata ttacaaatga ggtaacaata atgaagaaaa aatatgattt
      481 tttaatttat tctgctattt ggctagttat tattattctt tttatatttt ctctatatca
      541 cagtatagag catattaaaa ttataagtca cactggtact attcgtagtg aaactcaaaa
      601 ggttgttaag caagaattga ataatgaaag aaatgatgac ttgataaaac gactggataa
      661 tattctgata aagctaagaa caggtaatgg agaaaatgga tttcaaagat gtgataataa
      721 agaatttcaa caaaaactaa atcaaatgga ttctatgtgg gaatctatga agaaagaaat
      781 tataaaagtt agaaatggtg cttcaggtga taaattatat aaattgagtg aagagtattc
      841 tgtgttgtct aatcaaattg tttttatatc tgaaaaacac tctaatgcaa aattgtattc
      901 ttttgctact gcactattta tttatcttat attctcaaca ataagtcttt taatttggga
      961 atattataat aaaaaaaggt ttaaaagaat attttatact gataatttaa caaaaataaa
     1021 aaatcaggtt gcatttgaaa acatagcgat tgaaattttg cacaatgcat ctaacaaaga
     1081 gtatgtactg ctaaatattg atattgacaa ttttaaatat attaatgata cacatggata
     1141 tgaatatgga gataaagttc taataatagt tgcagctgca ctttctaaaa cttttaatat
     1201 caaagaaact tgtgcaagaa ttggttcaga taactttgta atacttgcaa aatatagaga
     1261 ttctctttta gaggatattc gggaaatgct aactaatgct ataatctctg aattagatat
     1321 gaatgtaact caaactatat cttattgtat aggagcgtac ttagttgaaa ttgataattt
     1381 aggttataaa tccatcaatt ctataatgga taaggcaaat attgcacaca aggtaagtaa
     1441 aacaagagga atttcctcca cagtatggta taatgaaaat ctgttaaaac agttacaaat
     1501 ggaaaatagt atttataatt atatgtataa agcgatagaa aatgaagaat ttcatatgta
     1561 tttgcaacct aaatttcaaa tatcttcttt aaatgttgta agcgcagaag ctcttgtaag
     1621 atggttttct ccagaacttg gttttttatc accagatgaa tttattccat tgtttgaaaa
     1681 aagtggattt attattgaat tggactttta tatgttaaaa aaagcgtgtt catttgtaaa
     1741 aaaaacgttt atgaaaaaaa tcaatataca tatccgattg cagttaattt ttcaagggtt
     1801 actatttacc aaaatagttt ttatcaaagg tttttagata ctgttaaaga atatgaaatt
     1861 ccttttaagt atatagagat agaggtaact gaaagtgctt ttaatgaaat atctcaacca
     1921 gttatttcaa ttttagagga acttaaaaag ttaggatttt taatttcaat ggatgatttt
     1981 ggttcaggat actcttcatt aagtctttta tgttctctat ctattaatgg attgaagtta
     2041 gataaaagct tacttaaaga aacctttaac cgggagaaag tatatagtat tattcaatgt
     2101 attattgaaa tgtcacatcg tataggcatg tctgttgtat gtgaaggtat tgaaactaaa
     2161 aaagacttgg aatttttaaa tacagttaaa tgtgatgtag gacaagggtt ttatttttct
     2221 aaaccgatag aagaaaaaga attttttaac aaatatgtaa ctaaaaaata atataattat
     2281 ttttatcagt ctatacattg agtcatttta tatctcgtta aatgactcaa tgtattgtta
     2341 tgtattttaa aatataaatt atttaaaacg ttttttgtac ttatatagaa attcttctat
     2401 attttttgat tgttctctta tttcaactgc ttctatatct agtaaataaa gtatagaatc
     2461 atttgtaagt tcaacatatt caccatcttc tgaaccgagt gcatgtctct caatttttaa
     2521 tcctttttct tcataatatt tttttgtttc tatatatagt gattctcgct tttgtatgta
     2581 gtctttcact tcattatttg gaaagttata tgaatccact aatgtttcgc catttataaa
     2641 agttttctcg gtagcaactt tttcatccca acaatggatt tcttcccaag taaaaaatat
     2701 ctcagttcca tctggaatga atgaaaacct ggtaataata tataaataat tattgaaatt
     2761 tacttcataa tattcaggaa tatcttcaaa ttccatatag taatttgtat aattaaaatt
     2821 actattatct ttttttacaa agggtatttt ttcaataaat ttatatattg attgttcatt
     2881 tttaaaaatt cctatatcat aacttttttc aaattgatta atttttaata aatacaacat
     2941 tctttctcct tttattcaaa atataatttt tataaattta ctaatcttta gcttttttaa
     3001 ttatat
//
LOCUS       DAEPUT010000172         2984 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.177, whole genome shotgun sequence.
ACCESSION   DAEPUT010000172 DAEPUT010000000
VERSION     DAEPUT010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2984
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.177"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     regulatory      21..114
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            197..682
                     /locus_tag="KRL22_003833"
     CDS             197..682
                     /locus_tag="KRL22_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1274252.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
     gene            1038..1436
                     /locus_tag="KRL22_003834"
     CDS             1038..1436
                     /locus_tag="KRL22_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274253.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNARRHNIL
                     TKLILSIIVIFLIIVLVVLIFIKRKKKKFY"
     misc_binding    1872..2135
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2286..2837
                     /locus_tag="KRL22_003835"
     CDS             2286..2837
                     /locus_tag="KRL22_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HBH1274254.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT         1286 a          265 c          439 g          994 t
ORIGIN      
        1 ttgttcaaat tatgttatta ttcagatata ggcaatatta gataaatcta atgacgcaaa
       61 actataggga ctaaaatctt tatgtaataa aggtcatgtc agccagttgc caaaaagata
      121 ataattcttt ttgttaaaag tatttttaga gttatatatt ttaataactt aatatttggc
      181 aagaggaggg cttaagatga tatctgaatt aatgttaaaa aattttcgca aatctagcat
      241 caattttaag actaaaatta aattgaattt aagagaaaaa ccagacataa atagtttgaa
      301 attaaaaagt ataccagaag gtaaaattgt taagttaaag tgtgtagatg gaatatgggc
      361 agaagttgag agtaattatg acaaaggttg gttactttat aaatatttag aaagattaag
      421 taatgctaaa aacaatagta atgatacaat aaaaaataga aaaaagaatt acataggaaa
      481 tataagaaca aatggattaa gtttagaact tagaaatgat agaacattag aatctaaagt
      541 tataactaca atccctgatg gttttaaagt tgaagtatgt tatagcgttg gaaaatgggc
      601 aagagttaat atcaataaaa atgaaaaacg atattctgga tatgtatata atcaatacat
      661 agaagagcat ttaagtttat aatacgatac tagcaagctt taaatatatt aataaatcac
      721 aaaaaagaat cccattaatg ggattctttt ttgtagaaac attataacag aactaaagag
      781 aataaattaa ctaatttatt tttattataa agtaattata aatggtaaat ttaattgaaa
      841 gtagatttaa cttatacttt atacaccaag tatcataaat taatactact ttgaaaaatc
      901 ttaaaaaaag taaaagttat gataataaaa ataatattaa agataataag atatataaga
      961 aacttgaaaa aatttgtaat ttttagttat atatatatta taatgaacta gttaaaaatt
     1021 tttatgaggg ggaaaatatg aataagaaga aaaaattgat tgggatagct atatcttttc
     1081 tacttataat cagcattata aatccattac aagtagaagc agaagctatt attgagtcta
     1141 gtgtatacat ttcttcaata aaagagaatt atacatatga taatactaaa tttaaaacta
     1201 ttaaatctaa aagtagacat aaaagtagga aatataataa aagtaaagta aagttgaaaa
     1261 aacgaagtat aagaactaaa aagtatggat atcaaactat aaataaatat aaaagacaaa
     1321 acgcaagaag acataatatc ctaacaaaat taatattgtc cataatagtc atatttttga
     1381 ttatagtttt agtagtgcta atatttatta aaagaaagaa gaaaaaattt tactaaaaat
     1441 aattaaaaga atatcatttt tttaatcatt ggtatctatt taataatatg atgtaattaa
     1501 aatggagtaa tattctgttt caaaggaggc atataaatac aggaatgagt attaaatgat
     1561 ggttaattaa gtaaatttat tgataaaggt acttaattaa ctttgaagaa tttaattcct
     1621 catgaatcaa aatataaaat tacattaaca gttattcaca aaattaatat aagaagaatt
     1681 agagccaaag agcagactat tagaccatta aagtaattat tcatagaatt ttgtatatga
     1741 aaagaaatgt atagtataat ttactttttt tataaaaaat agattacaaa atatattttt
     1801 tataaaaagg tattgacatt ttttagaaaa aagaatatca ttattttaat aacaaaattc
     1861 aatacaataa attaaatcct atgacaagga agagtagtta aatttaggtt cagtatagag
     1921 agctgaggat ggtggaatct tagcaagaaa aaatttgatg aatggccctt agaggaataa
     1981 attgaaatca tagttttgag agtagacttt atcgtcagtc gcacgttata gcgaataagg
     2041 tatgtaagta cctgataatg agatgtatga aaattgaatt ttatattaat ttttatataa
     2101 tttaggtggc aacgcggata atctccgtcc tattagttta ggacggagtt ttttatttta
     2161 ctgaaaattt aaaagataga aggtggtgag aaagatgtta tgaatttcaa aagctaaaga
     2221 tgatgatata gtaggttggc aaaaaaataa attgaaaatt aaaaaaatag gaggaagtac
     2281 aaaaaatgaa aacaaataca aaaaaattaa ctttaaatgc aatactttta gcgatgggat
     2341 tattaataca tcaaatcaca ccagctatag gattaccaat gaagccagat gtaccactag
     2401 caatgttatt tgtaatattg gttttaaata gagatgatta taaaacttgt ttgatagcgg
     2461 gtatagtaac aggaatattt acagcactta catcaagttt tccgggaggt caaattccta
     2521 atgtaataga taaaactctt acagcaaata tagtattttt attaatgaat attagttata
     2581 atatgccttt tataaaaaaa ttagctaaga aaacacaaga tactgtagta gttgcaataa
     2641 taatgccaat aggaactctt gtaagtggaa ctatcttttt attagcagct caagctatag
     2701 ttggtcttcc aggggcttca tttacagctt tattcttagc agtagtatta ccagctgttt
     2761 taataaatct agttgcagga atatttttat tcaagattgt tagtctatca ataagaagag
     2821 ttagttatca agcttaaaca cgaaataata ttttacttta taaagcatta taataactaa
     2881 ataacataag aataaagtag attataacta ttttattctt atgttgttta aagatttggt
     2941 attatatatt tatttttaat aaaatattta tatagtacca atta
//
LOCUS       DAEPUT010000173         2892 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.178, whole genome shotgun sequence.
ACCESSION   DAEPUT010000173 DAEPUT010000000
VERSION     DAEPUT010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2892
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.178"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            188..1111
                     /locus_tag="KRL22_003836"
     CDS             188..1111
                     /locus_tag="KRL22_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBH1274255.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1086..1913
                     /gene="panB"
                     /locus_tag="KRL22_003837"
     CDS             1086..1913
                     /gene="panB"
                     /locus_tag="KRL22_003837"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBH1274256.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDDCDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            1932..2780
                     /locus_tag="KRL22_003838"
     CDS             1932..2780
                     /locus_tag="KRL22_003838"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBH1274257.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
BASE COUNT         1167 a          339 c          461 g          925 t
ORIGIN      
        1 ttttatagaa ttaattgtca attttttatg aaaatggtaa gatatttatg gatggtatct
       61 tgttataaga actatacttt aaatgttttt aattattttg tcttatgtaa ctcatatcct
      121 caggaatgag attagaaatt aagatgttgt atcacaaagt ggaggtgata ctattaaaat
      181 aggctttatt ggttctggaa aagttggaac atctttggca aattattttt tatcaaaagg
      241 ttattgtgtt tcaggctttt atggaaggaa tcaattatct ttattagaat caacaaattt
      301 aacaaaaaca aagatttaca gcaatttgaa agatataatt tatgaaaacg atatattatt
      361 tattacaaca tcagatgatt ctattgaaat tatagacaaa aaactttcca aatttaattt
      421 aaaacataaa tacatttgcc acacaagtgg ctctttaaaa tctagtatat tgttctgttc
      481 aaaaaaagca ggtgcattaa tttattctat ccatcctata tttgcatttt ccaataaaaa
      541 taccaacata aaaaaaatga aagacatttg tttttccata gaaggtgata atgaacaaga
      601 tgatttagtt attcaaaatt tcatagatga tttgggaaac caatttttta taagagataa
      661 ggatacttca tccacttatc atttagctaa tgttttagtt tcaaatttag tattatcttt
      721 actagatata ggagtaagtt actttattaa attaggttta tctgaagagg aatctttaaa
      781 agctatcagt cctttagtaa aaaaaaatat agaaaatata cttgataatg gctttactaa
      841 agctcttact ggtcctgttt ctcgtggaga tataacacca ataagaaaac atctatctgt
      901 attggataaa aaagatgagg atatttacaa aatactatcc ttaaacctac taaaaataat
      961 tgccttagga aatgacaatt cattaaaagg tataaaaaat attactatag aaaatgcaat
     1021 cgaaaattta ataagtaaat ctgaaaaata caaagaaatt tacaaacttt taggaggaaa
     1081 aaacgatgaa aaataccata cagactttta agaatgctaa atatgaagga aaaaaactat
     1141 ctatgcttac tgcttatgac tactcaattg caaaaataat ggatgattgt gatataaatg
     1201 gtattttaat aggagattca ttaggaatgg ttataaaagg tgaagaaaac actctatctg
     1261 ttaccataga cgaaattata tatcatacaa aagctgtaaa aaatggtgta aaaaatgcct
     1321 taatcgtaag tgatatgcct tttctatctt accatgtttc tatagaagat gcagttaaaa
     1381 acgctggtag acttataaaa gaaggaggag ctcatgctgt aaagttagaa ggtggctcaa
     1441 acgttataaa gcaaatagaa agcattgtaa atgctcaaat acctgtaatg gggcatttag
     1501 gattaactcc tcaatcagta aattcatttg gtggatttaa ggttcaagga aataccagtg
     1561 aaacagcaag acaacttatt gaagatgcta aattaataga aaaagcaggt gcattctcta
     1621 ttgtccttga aggagtgcct acgaaaatag ctgagatggt aactaattct atttcaattc
     1681 ctacaatagg tataggagca ggaattaact gtgatggaca aattttagtt tatcaagata
     1741 tgttgggaat gtttggagat tttgttccta agtttgtaaa gcagtatgca aatataggag
     1801 atataatgaa agattcaatt aaaaattaca tcctagaagt taatacaggt gcatttccac
     1861 aagaaaaaca tagcttttca ataaatgaat ctgagttaga aaaattatac taatattaag
     1921 gatggtacaa aatgcttgta aaagaaatta aattactaag aaatataatc aaagattgga
     1981 gaaaacatgg ctattctata ggccttgtta caacaatggg atttttacat gaaggacacc
     2041 aaagtcttat aaaaaaagct gtaaaagaaa atgataaagt agtagtgagt gtatttgtaa
     2101 atccaactca atttggacca aatgaagatt ttaatagcta tccaagagat atagataaag
     2161 attttaaata ttgtatggat agtggagcaa cagtagtctt taacccatca ccagaagaaa
     2221 tgtatttaaa aggtaattgt actaccatta atgtttctgg acttacagat tttctttgtg
     2281 gagctaaaag acctgttcat tttggaggtg tctgcctagt tgtttcaaag tttctaaata
     2341 tagtaacacc tgataaagct tattttggag agaaggatgc ccaacaatta gctgtaatta
     2401 aaagaatggt caaggattta aacatagata cagaaataat aggctgtcct ataattcgtg
     2461 aaaatgatgg attagcaaaa agttcgagaa atacatatct ctctgaggaa gaacgaaaat
     2521 ctgctctaat attaaataag agcttaagtt tagcaaaaga agaattagta aaaggcaatc
     2581 taaatccaga gaatataaaa gaattaataa cagctaaaat aaattctgaa cacttagcaa
     2641 aaatagacta tgttgaaatt gtagatagtg agacattaca acctgttaag caaatagaac
     2701 attctatact tgtggcaatt gctgtgttta taggaaaaac cagactaatt gataatttta
     2761 catttgagtt aaatatatag tctataattt tatataatat atctaaaaaa taatagaata
     2821 cctaaaaagt aataaattac ctaaaaaata ataaattgct tagaaaataa tagattacaa
     2881 taactaaaat tt
//
LOCUS       DAEPUT010000174         2878 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.179, whole genome shotgun sequence.
ACCESSION   DAEPUT010000174 DAEPUT010000000
VERSION     DAEPUT010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2878
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.179"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            70..2427
                     /locus_tag="KRL22_003839"
     CDS             70..2427
                     /locus_tag="KRL22_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBH1274258.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYEAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(2513..2830)
                     /locus_tag="KRL22_003840"
     CDS             complement(2513..2830)
                     /locus_tag="KRL22_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBH1274259.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         1077 a          325 c          475 g         1001 t
ORIGIN      
        1 aaattgagaa ttttataata tatttgtaga tttgagtata aaaaagtgct aagttgaaag
       61 gagtaaaata tggataaggt taatttagaa aggtatagtt gtgatataaa tgttggttta
      121 aataaaaatc aacttcaaag tagaatagat gataatttaa ttaatgcatt tgataatgga
      181 aaaaccaaaa catataaaca aatttttaaa gacaatatat ttacactttt taatctcata
      241 aatattgttt tagtctgttt attagtttca gttggttctt ttaaaaatac cttatttata
      301 tttattgctg taattaatac tattatagga gtaatacaag agataagagc taaaagatta
      361 ttggacaatc tatctgttat agtttcaaat aaggtatctg tcataagaga aaaagagaaa
      421 aaagagattg atgtacaaga attagtatta gatgatatta tgattttaaa aacaggtaat
      481 caaatttgtg cagattcaaa agttttaaat ggaaaattag aggtaaatga gtctttggtt
      541 acaggtgaat ctgatattat tataaaaaat aaaggcgatt ttttatattc tggaagtttt
      601 gtagtttctg gagaagcttt tgtaagagtt gaaaatatag gaaaagataa ctatgcaaat
      661 aagatagcta atgatgcaaa gatttctaaa aaacataatt ctcaacttag aaattcatta
      721 aatgcaatat taaaaattgt aggtataata ataattcctc taggaattat attgtttgca
      781 aaacaacatt ttggaaatgg agattctata gctacatctg tagtaggtac agtggcagct
      841 gtaaatggta tgataccaga gggattaaca ttacttacga gcattgctct agctgtagga
      901 actataaaac ttgctagtca taaaacttta gtgcaagaac tgtactgtgt agagactctt
      961 gctagagttg atacactatg tcttgataag acaggtacaa ttacagaagg taaaatgcaa
     1021 gttgatgata tagtaatgtt ggaagaagtg gatattaatg aaataatggg gaatatatgt
     1081 aattctctca aagatgataa tgcaacacta aatgcaataa gagataagta taatgtttta
     1141 gatacgtata aagctaagaa tttaatacca ttttcttcag aaagaaaata cagtggggtt
     1201 acctttgaaa ataaaggtac atatttatta ggtgcatttg aatttatatt taaggaaaaa
     1261 aataaaaaac ttaggataga agttgaaaga tattctaaaa aaggaaacag agtaatagtt
     1321 ttagctcata gtgattctta tatggaagat aataatattc ctgaagatat aaagccacta
     1381 gcttttatat tgatattgga taaaattaga gatgaagcta aggaaacttt agaatttttt
     1441 tacaatgaag gtgtagatat aaaaattata tctggtgaca atcctataac agtaagtgag
     1501 gtagctagaa aagcaggtct taaaacagct agtaatttta ttgatgcaac aacacttaaa
     1561 aatgatagtg atatatacga agcagttgat aaatacagtg tttttggaag ggtaagccca
     1621 caacagaaaa aacaaatgat tttagcatta aaaaaacaaa atcatacagt agctatgact
     1681 ggagatggtg taaatgatgt gctagcactt aaagaagcgg attgtagcat tgccatggca
     1741 tctggaagtg atgttactaa gaatgtgtct aatttagtct tattagattc aaactttgca
     1801 tcaatgccaa aggttgttat ggagggaaga aaagtaatta ataacattca aagagcatct
     1861 tctttgtttt tagtaaagac aattttttca ttcttcttgt cgttattaac attattcttc
     1921 ttcagtagac agtatccatt tgttcctata caattatcac tcattggggc tgtaacagtg
     1981 ggtataccat cattcttctt agctcttgaa gcaaacaaaa gtagaatttc aggaaatttt
     2041 ttactcaata tattaaaaaa tgctttacca ggagcactat gtgtgacagt aaatgtaatt
     2101 attgtttaca atatagttga atatttaggt tatagttcaa gtgtattttc cacaatgtgt
     2161 gctatattaa ctggtgtatg tggtctttta atattaagac aacaatgttt gccatttaat
     2221 aaagaaagat tatttttaat agtaagtatg actattgcat ttgttattgg gattctattt
     2281 ttaggtggat tattctcatt tgtagcattg agtagagaat taattctcat aactatggca
     2341 ttagcaatat taatgccaat tatgataaaa gttatgttat ttgtcttaga tgagatatta
     2401 gagacaattg ttccagattt aaattaattt taaaatgata taaataagag cagttttagt
     2461 tgaactgctc tttttagatg tgtttaattt tatgtaagaa tatgtatttt tattaatcag
     2521 ctatatatga gcaacagtag tcaacaactt cattaacctt taagtcaaaa cttgaatcac
     2581 taggaacatt aaatttttga ccttctttat aagttacaaa ctcattgctt ccaggcagtt
     2641 ttacatccat acttccagca agcatctcca ttatttcttc ttctctagta gaaaaagtgt
     2701 attctcctgg caacattaat cctaaagttt ttctttctcc attaggcagt attattactc
     2761 tgctacttac cttaccatca aaataaacgt ttgccttctt tactgcagta acattcttaa
     2821 attcactcat tagataaaac ctccaaaatt atttgtacat atatattata taaaaata
//
LOCUS       DAEPUT010000175         2816 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.180, whole genome shotgun sequence.
ACCESSION   DAEPUT010000175 DAEPUT010000000
VERSION     DAEPUT010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2816
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.180"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(360..1256)
                     /locus_tag="KRL22_003841"
     CDS             complement(360..1256)
                     /locus_tag="KRL22_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1274260.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFFFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASHVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHKEVSNVILKEDMK"
     gene            1397..>2816
                     /locus_tag="KRL22_003842"
     CDS             1397..>2816
                     /locus_tag="KRL22_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1274261.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKN"
BASE COUNT          963 a          385 c          327 g         1141 t
ORIGIN      
        1 ttgactttct tttaattctt taggatggat ttaaattttc tataaaaatc atactatttt
       61 agctgtttac ttgcttattt aatagtttta tttctttgat taaatatctt tcagaatcta
      121 agccagatgt ctcaaaaaaa ctgatttata atataatcat tttttctgct attcttattt
      181 ttccaatttt agtttcatat taaaatatac ttttcataga cactacattc tttcatactc
      241 attttcacat ttaactatac aagtagtctt actcatttat gtactatact ttattaatat
      301 ttattaagaa aaactcaaag atttaaaaat atatattttc tataaagtat atttatgaat
      361 tatttcatat cttcttttaa aataacatta ctaacttctt tatgttcatt tctatactta
      421 gttggagata tattataatt ccttttaaat aagcgactaa aataatttat gctatcaaag
      481 ccacatctca tagcaatttc tgtcatattt aaatctgttt cctttaaata atatatagct
      541 ttatcaagcc tgattccatt tataaaatcg attgtagtct tacctgttat ttgcttaaat
      601 gttctacaaa agtgatgtgc actcaagttc acatgactag caagttcttt taatgtaatt
      661 ttatccatat atttttcttc tatcaaatca aagatacatt caaatttttc taaagaatac
      721 tttcttttta taaattcatc ttcagaatat attttatcaa tatgacttct taataagagt
      781 actattaatt gatagatatt agcttttata gataactcat atccaacttc tttattgtga
      841 tattcatcaa gtatagttgt aatacatttt aaaatcagag aatcattttg aattaaatta
      901 ttaaatacaa tatgatttaa agccaatggt gctaagtact tggtttgtaa caaatcaact
      961 tgattactaa aaaagaatgt gggttcaata cgaatactat agaattttaa attatctgat
     1021 aagctttcta aataatgtaa ttcattactg tttgctatta caatatttcc aggcactacc
     1081 ttaaaattat ccaatccaca ttcaagatat gctataccat caataaaata atatatttgt
     1141 agatgctcat gccaatgtct tttaaagttt gctccttttt taatgtcatc ctttaaaaaa
     1201 atatctataa agttttcttg acctttcctg ttaaaatatg tatttttatc cttcattatt
     1261 cccccctcat caaaatagtg ctaattataa gcaatatagt tattgtattc attatttcat
     1321 atcgctatta tataaaatgt aactatcatt gtaaacatta acataatgca gtcattataa
     1381 taaggaggta ataaaaatga caaactcttt taaaaaagat gataatagaa aaaaaatcac
     1441 agttttattt gtagtcattg ccatgacttt tatggcaaca ttagattcta gtattataaa
     1501 tgttgctctc ccagttcttg caagcaaact aaatgtatct ctagcatcta ttgaatgggt
     1561 aatagcaagt tactcaatta ttatttgttc aacactatta ttttttggaa gacttggaga
     1621 tattattggt aaatcaagag tatttcaagt aggtactatt ctctttacat cagcttcatt
     1681 actatgtgga ttaagtaatt ctttaacttt acttatagtt tgccgcttta ttcaaggaat
     1741 aggcgcttct gcctacatgg caaacaatca tggaattatc acagaactat ttccaaaaga
     1801 aagcagagga aaagccctag ggattttagt tactgcagtt gctattggaa atatggttgg
     1861 accatctgtg ggaggattta ttttgtcaat atttgattgg aatgttatat tttttataaa
     1921 tattccaatc ggtcttattg taatcttttt aaatacaaaa tttcttccta atagtaaaaa
     1981 atcttcagaa aatatggata aaactggtgc tatacttcaa tttttaggaa caacattatt
     2041 ttttagtgct ctaattagtg ctcaacaaac aggattacta aatccatata tattaattgc
     2101 actattatta tcaattattt ttattatatt atttttgata ttagaaaaaa aacatcctca
     2161 accgcttctt gaccttgaaa tttttagaaa ttttaaattt tcattgaatt taatttgtgc
     2221 tcttacatca ttcatttgta ttgcatcatc aagtatttta attccatttt atttacaaag
     2281 tactatgaaa cttcccccta ttcaagcagg tttatttatg atactatcac ctttgatttt
     2341 agccattttt tcacctatat ttgggaatat atcagataaa attaagtcag aaaaaattat
     2401 tttaattggt cttctcgtta tgagttttgg attctttcta atgtcaagat tgaaagaaag
     2461 ttctgccctt attttatttg taatttatat atcgataata tcaataggac aagctatatt
     2521 tcaacctgct aacaatgctt tgataatgtc aagctgttct agaagtaagc taggagttgt
     2581 aggaagcata aattcccttg taagaaattt aggacaagtt ataggtatta ctatttctac
     2641 aacactttta tataatttta tgagtattaa agctggatat agggtcaatg attatgtgat
     2701 taataatgat aaaatatttg tatttggaat gagaaatgtt tatattattg ttacacttgt
     2761 ttgcttaata ggtgcaatat taattggctt ttatttattt aaatataata aaaatg
//
LOCUS       DAEPUT010000176         2712 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.181, whole genome shotgun sequence.
ACCESSION   DAEPUT010000176 DAEPUT010000000
VERSION     DAEPUT010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2712
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.181"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            692..2599
                     /gene="ltrA"
                     /locus_tag="KRL22_003843"
     CDS             692..2599
                     /gene="ltrA"
                     /locus_tag="KRL22_003843"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015535382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBH1274262.1"
                     /translation="MPKKSKTLCVDDLRHAEYYGMQDTFDELYQKSQNGEVFENLMDL
                     ILSRDNILLAYRNIKANKGSYTAGTDKKNITDIGSRTPDDVVKRVRFIVTGSEHGYRP
                     KPVRRKDIPKPNGKTRPLGIPCIWDRLIQQCIKQIMEPICEAKFSNNSYGFRPNRSVE
                     HAINRTYTMLQMMNLHYVIEFDIKGFFDNVNHSKLIRQIWSLGIHDKTLIFIIKRILT
                     APIKMPDNTTVLPDKGTPQGGIISPLLANIVLNELDWWIASQWEENPIAISRGRERII
                     GKTKVFDKSHGYRIMKNTEMKEMHIIRYADDFRIFCRTKEDAVRTKEAVTEWIEERLK
                     LEVSPEKTRIVNTRKRWSEFLGFKIRVRLKHHKYVVQSAICDKKVEIERAKLVEQAKN
                     IAKPREKKSCLSEIQLYNSMVLGIQNYYQLATCISIDCREFHRRVMTVLTNRLNTETG
                     SMLKREGGTITQAEKERFGQSKMIRYVSGIDQMIYPIAFIKNKIPMAKRSIVCSYTKE
                     GRALIHTELNLNQYVLKGLREKISVGHSTEYHDSKISLFSAQKGKCAISGEEFADAEH
                     VAVWLKVPGSLGGFERYKNMVLIHKKYLILLQELPQAAIKDLIKTLNITKKMLVKINS
                     LREQANLSAII"
BASE COUNT          968 a          449 c          650 g          645 t
ORIGIN      
        1 gtaaaaagtc tgcgcacagt gttggtttat taaataataa ccagtctgtg aactggtaat
       61 ccgataggtg gaatgatggg gtaacgccct gaaacgtcta tccttgacgg acttgcgtca
      121 gctgtaatgg ctggggtgag aagctccgtg acaacgaccg agagtagtcg taggaatctg
      181 ccaaaagatt ctcgaaaacg ccccagaggt ggggtgcgct acctataggt ctaggatcta
      241 taaaatatct atggttagaa tgtttacttt ggcgagtaaa ctgacgaaaa ctgcgaatgt
      301 acggttctaa aagaagacca tatagaaatg tatgggtgcg ttaaagcgca gtcagtgtgg
      361 ttcagtagaa attgacccta cgaacgacca tgttgtgtta caggcacatc caagctgaca
      421 ggactatagc agagacctaa ggatatatgt acagatagga ttatcggaac gtggaaaggc
      481 atcagattcc attatgggat agcctgacga agaaaataag caggtgaact ggtgctgaaa
      541 agccgtgatc gaacttatga tgagttctgc gaaaaagagg aactcggagg aatggtcaca
      601 agtcggttga aataaacagg cattattcag tcttatgata aggattacga gtaagaccaa
      661 aagggtcact ttcgagagga ggtgatgcct tatgccaaag aaaagtaaaa cattatgtgt
      721 agatgacctg cgtcatgcgg agtactatgg aatgcaagat acttttgatg aactatatca
      781 aaaaagtcag aacggtgaag tatttgagaa tcttatggat ttgatactga gcagggataa
      841 cattttactt gcgtaccgaa acatcaaagc gaacaaaggc agctacacgg caggaacaga
      901 taaaaagaac atcacagata ttgggagtcg aactcctgat gatgtggtaa aaagagtgag
      961 atttattgtt acgggaagcg aacacggcta cagaccaaag cctgtaagac ggaaagatat
     1021 cccgaaacca aacggaaaaa cacgtccgct gggaatccca tgcatatggg ataggctgat
     1081 acagcaatgt atcaagcaga tcatggaacc aatctgcgaa gcaaagttca gcaataatag
     1141 ttatggattt cgtccgaaca gatccgttga acatgccatt aacagaacct acaccatgct
     1201 tcaaatgatg aaccttcatt atgttattga gtttgatatt aaaggatttt tcgataacgt
     1261 aaatcatagc aagttaatca gacagatatg gtcgctgggt atccatgata aaacgctgat
     1321 ttttattatc aagcgaatac taacagctcc aattaaaatg cccgataata caacggtatt
     1381 gcccgacaag ggtacaccac agggaggaat tatctcacca ctactggcaa acatcgttct
     1441 aaatgaattg gattggtgga tagccagtca atgggaggaa aatccaattg ctataagcag
     1501 agggcgagaa agaataatcg gaaaaactaa ggtttttgat aaaagccatg gttataggat
     1561 tatgaaaaac acagaaatga aagaaatgca tatcattcgg tatgcggacg attttaggat
     1621 tttctgtaga acgaaagagg acgcagtcag gacaaaagaa gcggttacgg agtggattga
     1681 agagaggttg aaattagagg tgtcccctga gaaaacaagg attgtgaaca ccagaaaacg
     1741 gtggtcagag tttcttggat tcaaaataag ggtaaggttg aagcatcata aatatgtggt
     1801 gcagtcggca atctgtgaca aaaaggttga aattgaaaga gcaaagctag tggaacaagc
     1861 gaaaaacatc gcaaaaccca gagagaaaaa aagttgttta tcagaaattc agctatataa
     1921 ctctatggtg ttaggcatac agaattacta tcagcttgcc acctgtatca gtattgattg
     1981 cagagaattc cataggcgag taatgacagt tttgacgaac aggttaaata cagaaacagg
     2041 aagtatgcta aaacgtgagg gtggaactat cacccaagca gaaaaggaaa gattcggaca
     2101 gtcaaaaatg attcgatatg tttcaggaat tgaccagatg atctatccga ttgcattcat
     2161 caaaaataaa ataccgatgg cgaagcgatc aatcgtttgt agttatacaa aagaaggtcg
     2221 tgctctgatt catacagaac ttaaccttaa tcagtatgtt ctgaaaggac tgagagaaaa
     2281 aatatccgtt ggtcatagca cagaatacca tgacagtaaa atatctttat tttctgctca
     2341 aaagggaaaa tgtgcaatca gtggagaaga attcgcagat gcggaacatg tagctgtatg
     2401 gctcaaagta ccaggatcac ttggtggatt tgaaagatat aaaaacatgg ttctgattca
     2461 caaaaaatat ctgattctgt tacaagaact gccccaagca gcaataaaag acctgataaa
     2521 aacactcaat atcacaaaaa agatgctcgt gaaaatcaat agtctgcgag agcaggcgaa
     2581 cctgtcagca ataatataaa acttaaattt ggtgactgat taaatgtctt gtgaagacaa
     2641 tcgatggagc gccggatgcg gtgaaagtcg catgtccggt gtgaagtggg ggaaaaggtg
     2701 gagataatat ca
//
LOCUS       DAEPUT010000177         2702 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.182, whole genome shotgun sequence.
ACCESSION   DAEPUT010000177 DAEPUT010000000
VERSION     DAEPUT010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2702
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.182"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            63..266
                     /locus_tag="KRL22_003844"
     CDS             63..266
                     /locus_tag="KRL22_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274263.1"
                     /translation="MISYAPLWKLLIDKKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
     gene            430..1593
                     /locus_tag="KRL22_003845"
     CDS             430..1593
                     /locus_tag="KRL22_003845"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013361911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBH1274264.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKEKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKKIGR"
     gene            1598..2602
                     /gene="rseP"
                     /locus_tag="KRL22_003846"
     CDS             1598..2602
                     /gene="rseP"
                     /locus_tag="KRL22_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBH1274265.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGKLKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
BASE COUNT         1059 a          281 c          517 g          845 t
ORIGIN      
        1 aatagatgaa aattttccaa aatagataaa atgtgataga atatattttg cgaggtgata
       61 acatgatttc atacgctcca ttatggaaat tgttaattga caaaaaaata aagaaaatgg
      121 aatttgtaaa tatatcaggt ataagtattt ctgttttagg cagactagga aatgataaat
      181 ctgtttctat ggatacaatg gagaagatat gtttagcact agactgtaaa atagaagatg
      241 ttgtggaaat aaaaaagggc atttaataat actagaatat tttataatat tccacaaaat
      301 acaaaaaata atagattaat tttaatctgt ggaataatat atgaaatttc tatgaatagt
      361 aaaaataatt gttttagtag tgttataatg ttttgacagg gtatatttat tattagaaag
      421 gattattata tgaaaaagat atcaatttta ggttctacag gctctatagg taaacaaact
      481 ttggatgtag ttagagataa tagagataag tttgagatag ttgcaatatc agctaacagt
      541 aatattgaat tattgctaga acagatagta gagtttaaac ctaaatatgt aacagttttt
      601 gaggaaaata aagcattgaa attaaaagaa atgttgccta aaaatataga aatagaagtt
      661 ttagcaggaa tggaaggatt aaaaataata tcatcacttg atgaagtgga tgtcctttta
      721 actgctgtag taggtatgat aggattagtc ccaactcttt gtgctataaa gaagggaata
      781 gacatagcat tagcgaataa agaaacgttg gtaactgctg gtgaacttgt aatgaaagaa
      841 gcagaaaaat acaatgtaaa tattcttcct gttgatagtg aacatagtgc tatatttcaa
      901 tgtctaaatg gagaaaataa aaaaaatata gaaaagataa tacttacagc atctggtggt
      961 ccatttagag gaaaggaaaa gggagaactt gcaaatataa ctaaaaatga agctttgaag
     1021 catccaaatt ggagtatggg aagaaaaata agtattgatt cttcaacgct tatgaataaa
     1081 ggacttgaag tgatagaagc tagatggtta tttggagtag aacaagaaaa tatagatgta
     1141 gtagttcacc cacaaagcat aattcattca atggtgcagt atacagatag ctcaataatt
     1201 gctcaattag gatgtccaga tatgagacta ccaatacagt atgctcttac atatccagat
     1261 agaatggaaa gtagctttga aagaatgaat ttttcaaaat ttagtacttt aacttttgaa
     1321 gaaccagatt tagaaacttt tccatgttta aaattggcat atgagtgttt aaaaatggga
     1381 ggaacttatt cttctgtttt aaattcagca aatgaagttt tagtaagtga atttttagag
     1441 gataaaattg gtttctatga cataccatat tacatagaga agactttaga agttcatagt
     1501 agcataagtg aaccaacatt agaagaaatc ttagaaacag atagatggag tagagcttat
     1561 gttgcaaatc tgataaaaaa aataggaagg tgaatttatg actataatag ccgcattaat
     1621 actatttagt ataattgtat taatacatga gttaggacat tttatatttg caaaaagaag
     1681 tggtatcaaa gtaaatgagt tttctatagg tatggggcct aagatatata gtgtaaaaaa
     1741 agatacagag tattctataa gagcacttcc aattggtgga tatgtcagca tggaaggtga
     1801 agatgaagaa caaataagtc caaattcttt tggaaacaag tctatattac aaagatttag
     1861 tactattgta gcaggaccaa tattcaatat aatattagca gcaatacttt tagtcccagt
     1921 atttttgtat ataggttctc caacgactaa attaggaaag ataatgccag atactcctgc
     1981 acaggctgta gggcttcaag taggagataa gataaataaa attaatggta attctgttaa
     2041 gacttgggat gaagttgcaa atataataaa tacttcttct ggtggaaaat taaaacttag
     2101 tataactaga gatggaagtg ataaagttgt aaatgtaaca cctaaaaata acaatggaaa
     2161 gtatgaaata gggattcaac cacaaagaga aaaagacttt ttggggtcaa tagtaaatgc
     2221 atgtaaaact actgtagata tgacaaaaca gatgctaaca tttctaggtc aaatgattac
     2281 aggacgtgta ccaggaggga ttggcaatgc tgtagcagga ccagtaggtg ttattggtat
     2341 ggtatcagat gctgctcgta caggcatcat aaatgtagtg tatttagcag ctgtcataag
     2401 cttaaattta ggtatagtaa atctattacc aataccagca cttgatggat ggagaatact
     2461 tatgctgtta ctagaagctg ttagaggtgg taaaaaactc gacccaaata aagaaggcat
     2521 gataaatgtt gttggttttg gagctttaat gttatttatg ctttttatca catataaaga
     2581 tatactaaga ttatttcaat gatttagttt tttagagatt ttaagaaaat aggctatgta
     2641 gttttaaata agaataaatt aatttttata tatgaaattt attcttattt aactagatag
     2701 ct
//
LOCUS       DAEPUT010000178         2603 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.183, whole genome shotgun sequence.
ACCESSION   DAEPUT010000178 DAEPUT010000000
VERSION     DAEPUT010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2603
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.183"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(250..1500)
                     /locus_tag="KRL22_003847"
     CDS             complement(250..1500)
                     /locus_tag="KRL22_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HBH1274266.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1533..2474)
                     /locus_tag="KRL22_003848"
     CDS             complement(1533..2474)
                     /locus_tag="KRL22_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HBH1274267.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFFDFNNLIGVAL"
BASE COUNT          791 a          497 c          240 g         1075 t
ORIGIN      
        1 aaaatatata acagtactat tataaataca catttaaaac cttataaata tacaaataca
       61 attatatgaa ttttcatcct caattatagc atagaatatg actatctata tcctaaaatt
      121 atccatttct aaaaaaaagg taactattat taagaatatc aacttataga atttatattc
      181 cacatacgat tttcaatcaa aaaaacaagg gctaaaaagt gaattgtgca ctttttagcc
      241 ctttattaat tattcattta tttcatgtaa gaatagacca catcttactt taggttcaaa
      301 ccatgttgac ttagctggca ttatcttatt tgcatctgct actcttatta aatcttcaat
      361 actagtagga tacattgcaa atgctacttt catatcttca ttaactcttt tttctaattc
      421 ttcaagacct ctaattccac cgataaaatc aattctttta tctactctag gattatcaat
      481 tcctaaaata gcatcaataa catagtcttg taatatagaa atgtctaatg agtcaacagg
      541 gtcttctatt tctaataaat ttttatttgc tttcatttta taccacttat cacctaggta
      601 cattccgaaa gttccttttt tgtcaggttt atatttttct tttccttcta tttcttctag
      661 ttcaaaattt tcttttattt tatttataaa ttcttcctcg cttaaaccat ttaagtcttt
      721 gataacccta ttataatcca aaaccattaa attctcatct ggtgcaatca ttgctatgaa
      781 gtaattaaat tcttcttttc cagtataatt tggattttta gctctcattt ctttggctac
      841 attttctgct gaagctgtcc tatgatgacc atctgcaatg tatagataat ctaatttttc
      901 aaatttatct actaggttat ctattatatc atcattatca atcttccata ctgtatgctc
      961 tatcttgtca tctgttatga aatcatataa aggttcatta ttatccataa aatcattgat
     1021 tatatcatct atcacccttt gatgtttgta agttacaagt atagttcccg tattagcatc
     1081 acagtatttt atgtgtttag ttctatcaat ttccttttct ggtcgagtgt actcatgttt
     1141 ttttattgtt ccattcaagc tttcatcaac tgatatacat gctactatac caacttgagc
     1201 tctaccatcc atgatttgtt tatatatata tatacactct ttgtcatctt ttactagaat
     1261 ttcttgtttt cgaaactcat ctaaattttc tcgcgctttt aaataaactt tttcatcata
     1321 taaatctata ttttcatcta aatcaatttc tgatttatct atatgcaaaa atgaatatgg
     1381 attcccttct gcaattcttc tagcttcttt actattcata acatcgtaag gaagtgctgc
     1441 tactttatct actatatatt tatttggtct aatcgcctta aatggtttaa tcgttgccat
     1501 tactaatttc ctccctaatt atacaaaata ttttataatg ctacccctat tagattgttg
     1561 aagtcaaaaa agaaatcttg aatcacattt actatttcgt ctcctattct ttcttgagct
     1621 tctactgtag atgccccaat atgaggtgta ggagaaactc ttggatgatt tactaagtct
     1681 aaatttaatg taggttcttg ttcataaaca tctatagcag ctgctgataa tttaccttca
     1741 tctaatgctt ttagtaaatc tttttcatca actaaaccgc ctcttgcaca gtttattaaa
     1801 taagcccctt tcttcatctt atttatttct ttttcagtta ttactgcccc cttattctta
     1861 tcaaatggta tgtgtaaaga taagaaatct gcattttcta aaacttcttc catatcacag
     1921 aatttataat tgttaaagcc ttgcgcctca cccattatgt cagtatatat aacattcata
     1981 cctaataatt ctgctctctt tgcaacttct tttgcaattc ttccaaaacc tataagtcca
     2041 agtgtctttc cattaatttc tgtaccttta tactttttct tctcccattt tccatctctc
     2101 atagttacat ttgcagtatt tatgaatctt gcaagaacaa ataattgacc tattgtaagc
     2161 tctgcaacag atatactgct tgcatttgga gtattcataa cttttatgcc attagcttga
     2221 gcatatttaa catctatatt atccagacct actccacctc ttactatcaa cttcaacttt
     2281 ttaccctcta atgctttatc tattacatct ttagtaactt tagtagctga acgtactaca
     2341 agtacatcaa catctttaag tttatctcct aaaacatctt tttcataaaa ctgctctatc
     2401 acattaaaat ctaactctct caattttctc gctgcttctt tctctattcc atcagtaact
     2461 aatatattat acataacaaa ctcctccaat ttttattcac ttaatttttc caatttttat
     2521 tttttaaagt attttcatca ataaaaaact ttacttaatt taactttctg tttatataat
     2581 tttcaaaata tttttttatt aaa
//
LOCUS       DAEPUT010000179         2571 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.184, whole genome shotgun sequence.
ACCESSION   DAEPUT010000179 DAEPUT010000000
VERSION     DAEPUT010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2571
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.184"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            60..1016
                     /locus_tag="KRL22_003849"
     CDS             60..1016
                     /locus_tag="KRL22_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HBH1274268.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            1193..1348
                     /locus_tag="KRL22_003850"
     CDS             1193..1348
                     /locus_tag="KRL22_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274269.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            1478..2491
                     /gene="aroF"
                     /locus_tag="KRL22_003851"
     CDS             1478..2491
                     /gene="aroF"
                     /locus_tag="KRL22_003851"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH1274270.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
BASE COUNT         1043 a          239 c          440 g          849 t
ORIGIN      
        1 attacagtaa tgattataaa aaatttttag aatgtaaatt gaaatttagg agtagatgta
       61 tgtatatact gaatttaaat acaagagaga ctattgaaga ttttagagat aaattttatg
      121 tagcagaaaa ttcttatctt atattaagtg ctccaaaaaa tttaaaattg cttaaggaaa
      181 ctttggatat agatgaaata acttttaatg attgtcttaa atttgatgaa ataaccaaac
      241 ttgatttatt tgataattac gattttttaa gcctaaatac atttgaacta agagatggag
      301 aagctgttat agaagaggta aatatgtatt tatcagataa ttttatattg gttgtagtga
      361 atgaagaaca ctttttattt gaatttgtaa aaaatattat tttgaagaac tctcaacttg
      421 aaaaaaatcc agttattaat ctatttaaga taaactactt gattcttaga gaagttataa
      481 aaaatggttt tgagtctttg gaaaaagttg aagagttaat tcttcaaata gaagatgaaa
      541 tgatggacaa cattaataag aatcatgtat ctagaataag tgatgtaaga ggattaacaa
      601 gaattatagt taagaatact agacctcttt tgtatattgg ggatagaata gttaaggaaa
      661 atataagata tttaaaatat tcaaatgtaa aaaaatataa tttagaaaat tttcaaggca
      721 tagattttgg aattgacaaa ttatacaatt tcgcattgtc aacacgagag ttagcagata
      781 aattattaga tatttattct tccagagtag gtgagaaaac aaataactta attacaaaat
      841 taaccttgtt aacagccata tcagcaccac ttacaattat aactggtata tatggaatga
      901 actttagata tatgccagaa ttaaactgga tttatggata tccagcaact ttatttttta
      961 tgctatgtat aatttttgtt ggaattataa tatttaaaat aaaaaaatta ttgtaaatta
     1021 cagatgatgt ttaattgatt ttataaaaat acatcaattg agaagctgat ttaagtaaat
     1081 aaaaaaatat tttaaattga aaatatttat agaaaatatt gacaattata ttttctttgt
     1141 tataattatt aaacaagaag aataataaat tataaaaatg gaggataata ctatgaaagg
     1201 aatattaaaa gaactaacag caaaacttta tagctttttt tactttatgt tctggggctt
     1261 ttattttagc gctggctatt tcttttacaa aaatatatgt acttcctttc tggtgaggcc
     1321 ttattttagt gattttgagc ataagtaaat tttataaaaa tgattatttt atatatttat
     1381 ataagattta gtgcttgata gattatttta gagaactcat tagtgagttc tcttttttat
     1441 tttaaatata aaattataat attgggaggt agtaaaaatg atagtagtat taaaaatggg
     1501 agcagataaa aatgaagtta aaaaattaat tgaggctatt gggagagaag gagtagaagt
     1561 taatcccata gatggaacag aattaactgt tttaggttta gttggagata ctagtaaaat
     1621 agatgccaaa agaatagaag caaataaggt agttgaaaaa gttatgcatg tggtagagcc
     1681 ttttaaaaag gccaatagaa aatttcatcc agaaccttca atcataaatg ttaatggaat
     1741 ggaaattggt tcaaagaaaa ttgctatgat agctgggcct tgttctgttg aaacagaaga
     1801 ccaaatagta tctatagcta aagatgtgaa aaaatcaggt gcaggatttt tgagaggtgg
     1861 agcattcaaa ccaagaacat caccatacgc tttccaagga ttgaaatatg atggattgga
     1921 tttattaaaa aaagcaaaag aaaaaacagg acttcctata gttacagaaa taatgtcaac
     1981 acaagatata gatatatttg aagaaaatgt agatgtaatt caagttggag ctagaaacat
     2041 gcaaaacttt gatttattaa aagaattagg taaaacaaat aaaacaatac ttttaaaaag
     2101 aggattatct gctacaattg aagagtggct aatgtcagca gagtatataa tggctggagg
     2161 aaatgaaaat gtagttcttt gtgaaagagg tataagaact tttgaaacat atactagaaa
     2221 tactttggat ttaagtgcaa ttttagctgt gaagaaactt agtcatttac cagttatagt
     2281 tgacccaagt catgcagcag gtaaatcatg gatggttgac tctttatcta aggcagcaat
     2341 tgcagttgga gcagatggtc taataataga agttcataat gacccagcac atgcactttg
     2401 tgatggaaaa caatcgatta agccaaatga atatgatgaa ttgataagtg aattaaagac
     2461 tatcgcatca gcagttggta gagaaatata atctataaaa ggatggttaa acgtggaaga
     2521 aaaactatta gtaaatttaa aagaaaatag ctacaatata tttattaaaa a
//
LOCUS       DAEPUT010000180         2567 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.185, whole genome shotgun sequence.
ACCESSION   DAEPUT010000180 DAEPUT010000000
VERSION     DAEPUT010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2567
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.185"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            396..2423
                     /gene="bclA1"
                     /locus_tag="KRL22_003852"
     CDS             396..2423
                     /gene="bclA1"
                     /locus_tag="KRL22_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HBH1274271.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGSIGP
                     TGATGPTGNTGVTGSIGPTGVTGPTGNTGEIGPTGATGPTGVTGSIGPTGATGPTGEI
                     GPTGATGATGSIGPTGATGPTGATGVTGEIGPTGEIGPTGATGPTGVTGSIGPTGATG
                     PTGATGEIGPTGATGPTGNTGVTGEIGPTGATGPTGNTGVTGEIGPTGATGPTGNTGV
                     TGEIGPTGPTGNTGVTGEIGPTGVTGPTGNTGATGSIGPTGVTGPTGVTGSIGPTGAT
                     GPTGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTLNNGDAITGWQTIIGNSSSIT
                     VDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAILFPILGGKDLAGLTTEPGGGG
                     VLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAATLTIFRIADTVMT"
BASE COUNT         1016 a          380 c          553 g          618 t
ORIGIN      
        1 tattttattt attctattta acaaaaataa agttttttat aatttttact tataaaaaaa
       61 tattgttatg gtaatatatt ctatttacaa ttttataact ttggtttaca ataatataga
      121 taataaatcc taaaaaacat aataagaaaa aagtgcttaa tattttagaa agactggttt
      181 agtttacacc agctaagcca gtcaaggaat aatttaaagt gtaatatata ataatgaaaa
      241 agaacatgct attagaaatt tctaatgaca tgttcttttt ttgtagaaat cagcattatt
      301 atataaaaat ttaatactat aaattttaat tgtattgtaa ctaagcatgt attttaaaca
      361 tagtatgata tagacccaaa atggagggat tataaatgag aaatattata ctttatttaa
      421 atgatgatac ttttatatct aaaaaatatc cagataaaaa ctttagtaat ttagattatt
      481 gcttaatagg aagtaaatgt tcaaatagtt ttgtaaaaga aaagttgatt acttttttta
      541 aagtgagaat accagatata ttaaaagaca aaagtatatt aaaagcagag ttatttattc
      601 atattgattc aaataagaat catattttta aagaaaaagt agatattgaa attaaaagaa
      661 taagtgaata ttataattta cgaactataa catggaatga tagagtgtct atggaaaata
      721 ttaggggata tttaccagtt gggataagtg atacatccaa ctatatttgt ttaaatatta
      781 caggaactat aaaagcatgg gcaatgaata aatatcctaa ttatgggtta gctttatctt
      841 taaattaccc ttatcagatt cttgaattta catctagtag aggttgtaac aaaccgtata
      901 tacttgtaac atttgaagat agaattatag ataattgtta tcctaaatgt gagtgtcttc
      961 caattagaat tacaggtcca atgggaccaa gaggagcgac aggaagtaca ggaccaacgg
     1021 gagtaacagg cccaaccgga agtacaggag cgacaggaag cataggacca acaggcccaa
     1081 ccggaaatac aggagcaaca ggaagtatag ggccaacggg agtaacaggc ccaaccggaa
     1141 gtacaggagc gacaggaagt ataggaccaa caggagtaac aggtccgaca ggaaatacgg
     1201 gagtgacagg aagtatagga ccaacgggag caacaggccc gacaggaaat acgggagtga
     1261 caggaagtat aggaccaaca ggagtaacag gcccaacagg aaatacagga gaaataggac
     1321 caacgggagc aacaggtcca acaggagtga caggaagtat aggaccaaca ggagcaacag
     1381 gaccaacagg agaaatagga ccaacgggag caacaggagc gacaggaagt ataggaccaa
     1441 caggagcaac aggtccaaca ggagcgacag gagtgacagg agaaataggg ccaacaggag
     1501 aaataggacc aacgggagca acaggcccaa caggagtgac aggaagtata ggaccaacgg
     1561 gagcaacagg cccaacagga gcaacaggag aaataggacc aacgggagca acaggcccaa
     1621 caggaaatac aggagtaaca ggagaaatag gaccaacggg agcaacaggc ccaacaggaa
     1681 atacaggagt gacaggagaa ataggaccaa cgggagcaac aggaccgaca ggaaatacag
     1741 gagtgacagg agaaatagga ccaacgggtc cgacaggaaa tacaggagtg acaggagaaa
     1801 tagggccaac aggagtaaca ggaccaacag gaaatacagg agcgacagga agtatagggc
     1861 caacgggagt aacaggtcca acaggagtga caggaagtat aggaccaacg ggagcaacag
     1921 gtccaacagg agcgacagga gtaacaggcc caacaggtcc aacaggagca acaggtaatt
     1981 cctctcagcc agttgctaac ttcctcgtaa atgcaccatc tccacaaaca ctaaataatg
     2041 gagatgctat aacaggttgg caaacaataa taggaaatag ttcaagtata acagtagatg
     2101 caaatggtac gtttacagta caagaaaatg gtgtgtatta tatatcagtt tcagtagcat
     2161 tacaaccagg ttcatcaagt ataaatcaat attctttcgc tatcctattc ccaattttag
     2221 gaggaaaaga tttggcaggg cttactactg agccaggagg cggaggagta ctttctggat
     2281 attttgctgg ttttttattt ggtgggacta cttttacaat aaataatttt tcatctacaa
     2341 cagtagggat acgaaatggg caatcagcag gaactgcggc tactttgacg atatttagaa
     2401 tagctgatac tgttatgact taaaacgtgt ctaaaataat cttaaaaact atttaggctt
     2461 tatttaaatg acaaaagtat ttttatatat tgagttttac ctattttaga atgaataaaa
     2521 taacaataat aataaaatat attcataaaa attttaaatt tatggat
//
LOCUS       DAEPUT010000181         2423 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.186, whole genome shotgun sequence.
ACCESSION   DAEPUT010000181 DAEPUT010000000
VERSION     DAEPUT010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2423
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.186"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            4..2022
                     /locus_tag="KRL22_003853"
     CDS             4..2022
                     /locus_tag="KRL22_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1274272.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIR
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
BASE COUNT         1010 a          294 c          408 g          711 t
ORIGIN      
        1 aatatgagaa gaaatacaaa attattaaca acagggattc tttcaatggc aatcgtcgca
       61 cctacaatgg catttgctac tgaatctaat gctatggaaa ataacgctga tttaaatata
      121 aacttagaga aaaaaagtat cgttttaggt agtacctcaa aagtcagtgt taagtttaaa
      181 gaaaaaccag atgcagatag cattacatta aagtataaat gctatgatat gccattggat
      241 acaactttaa actacaatca atcaactgag tcatatgaag gaactatcaa ttataataaa
      301 gacccagaat atctaaatgt ttgggaacta caagggataa caataaacag caaaaataat
      361 cctaaaactt taaacaaaca agaactagaa aagatgggat taaatttaaa agactataat
      421 gtaacacagg aatgtataat tgaagatata acttctagaa aagatgtaaa taaatattta
      481 agaaaaactt ctgcacctat tacagaactt acaggaagtg atagatacga aacagcagtt
      541 aaaataagta aagaaggctg gaaaaatggt tcagataagg tagttataat aaatggggat
      601 gtaagtatag atggcattat atcaactcca ctagcaacta catataatgc tccaatactt
      661 ttggttgaaa aaaacaatgt acctaatagt gtaaaatcag aattaaagcg tttaaatcct
      721 agagatgtaa ttataattgg agatgagaat gctatttcta aaactactgc taatcaaatt
      781 aaatcgactg taaatgctag tcaaacacgt ctaaagggct ctaatagata tgagacatct
      841 ttattgatag caaaggaaat agataaaaat catgatgtgg aaaaagtata cataacaaat
      901 gctaatggcg gagaagtgga tgcacttact atagcagcaa aagcaggtca agacaagcaa
      961 ccaattatat taactgataa aaatagtatt acagacaata catataaatg gttaaagagt
     1021 gaggatttac aaaatgctta ttttataggt ggccctcaaa tgatatcaac aaatgttata
     1081 aataaggtaa atgatataac taaagataat gttactaata atagagtata tggagcagat
     1141 agacacgaaa caaatgcaaa cgtaataaaa aaattctata cagatgatga gttagaggct
     1201 gttttagtag ctaaatcaga tgtacttgtt gatgctttag cagcaggtcc attggctgcg
     1261 aacttaaaat ctccaatact tataacacca aagacatatg tatctgcata ccataaagaa
     1321 aacttagaag ctaaatcggc aaataaggta tataaaatag gtggaggatt gacttctaag
     1381 gtaatgagct ctatagcatc atcattatct aaacacaata cgactccaac agaaccagga
     1441 aatagtgggg gcaagacagt tatgattgac ccaggacatg gtggttcgga cactggaaca
     1501 acaggtaaac cattaggggg tattagagaa aaagactata cattaaatac ttcacttgcg
     1561 acaactgaat atttacgttc aaagggattc aatgtaataa tgacaagaga cacagataag
     1621 actttatctc ttggaaatag aactgcttta tctaactctt tgagaccaga tttatttacg
     1681 agtatacact ataatgcatc tgatacaact gggaatggtg tagaagtatt ttataagctt
     1741 aaagataaag atggagggac tactaaaact gtagctacaa atatattaaa tagaatctta
     1801 gagaaattta atctaaaaaa tagaggtgca aaaacaagaa cactatcaac tgaccctaca
     1861 aaagattatt tatatgtttt aagaaataat gatatgccag ctgtacttgt agaatgtgca
     1921 tttttggata atgagaaaga tatgagttta cttaatacat caaataaagt aaaagaaatg
     1981 ggtacacaaa taggtaaagg catagaagat tcattaaaat agtctacaat gagagtatag
     2041 aaaaatttaa aataaattaa tctgcaattt taaatttaaa ctaaagctat aagataagaa
     2101 tgtaattata aatgtaatta taatagtaat aaagactgta tatacattgt gcatataaat
     2161 gcgaaatgag gtatatacag tctttttata attaattgta aaatgattta tgttatatga
     2221 aaaatttaca tatattaagg ctacagttaa ttgtcaagag ctggagtatt catttgtaat
     2281 acacaatata agcttaatta ctatatttta ttgtgtgttt gtgtgttttt tgtggatttt
     2341 tatgtcaata aatgatatag tatagataat taaatgtatt aaatatattt aattttttta
     2401 ttttttgagt tttataagtt tat
//
LOCUS       DAEPUT010000182         2414 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.187, whole genome shotgun sequence.
ACCESSION   DAEPUT010000182 DAEPUT010000000
VERSION     DAEPUT010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2414
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.187"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(134..1426)
                     /gene="brnQ"
                     /locus_tag="KRL22_003854"
     CDS             complement(134..1426)
                     /gene="brnQ"
                     /locus_tag="KRL22_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH1274273.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALASSVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGIK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          813 a          384 c          251 g          966 t
ORIGIN      
        1 aaatttttaa atttatcaaa taggattaat aatgttcttt tatctacaat aatttaataa
       61 ttcttttaaa tataaaaagg aattgcctat ataatttaaa ggcaattcca taattatcaa
      121 ttagttttta ttattatgca gttttactgc ttttagatgg aataaagttt cctattattc
      181 ctgctattac aactggaact atccagttaa atcctaatga agcaaatggt aagctattaa
      241 ctagaggaat ttttatacca aaacttgttg caactgttaa tacacttact aataatgcca
      301 tgtatgcagc acatttgaac acgttgtcat ttttaatttt attactaaat aatgctagta
      361 taactagagt tatagttgct ggatatacca tacttagtat aggagaagag aattgtatta
      421 ttgtacttac tccaaagttt gatatgattg cactaaatac acaaactact ataactatat
      481 gctcatactt taattttcca tctgtaagtg ttgagaaata ttgaccagct gctgaagaaa
      541 gacctatagc tgttgttaaa catgctaatg caactataat agccaataaa attttacctg
      601 tagttccaag taaagctgct gttattgcaa ctattaaagc tgtttgttga acatcttgtc
      661 catattgttg agacacagtt gctccaagat aacataatcc accataaact aatgccattc
      721 ctattactgc aattacacct gcacttattg tggctttcat cttttctttc tcacctgtat
      781 aacctttagc tattactgac atgattataa ttgatgcaaa tacactagat gccaatgcat
      841 ccattgtttg ataaccttga gttatacctt ctgcaaatac attttgtatt aaagaactgt
      901 ctcttatttc tcctaatgga gatacgatac ctttaactat taatactgct aaagctataa
      961 gtaaagctgg agttaatatt gacccaacta tatctacaac ttttgatggt cttattgtta
     1021 aaaccaatac tagagcaaag aatactatag agaatattac tgggcttatt ccagaaccta
     1081 ttgtaggtaa tatacccatt tcataagttg ttgctgctgt tctaggtatt gctaaaagtg
     1141 gccctataca gattaccatt gcacatccta atgcaatact taatcctttg cctgctcttg
     1201 agaacatctt cgatgtgtct ccattgaact tagttgctgc tataactgct aataatgcca
     1261 aaccaccatc tgcaaaaagg aatcctatga aagctactag ccaactactt ccagataaaa
     1321 ctcctagata tggagggaag attaagttcc ctgcaccaaa aaacattgca aatagtgcaa
     1381 atccaattac aattacatct ttaaaattga tttgtttctc acccatttaa agcaccccca
     1441 tttgaatttt actacctttt actaaaaaat aagtccaatc tcttaattaa atgaaaacct
     1501 tttgacgaga ttttatttaa ttatacattt ttgacttaaa tttgtcaatt atgtttcata
     1561 atttataaaa tcttcacaat atttaataca actttcttaa ttaaacaaaa tcaacctgta
     1621 tactttaaac atagttggtt ttttgttttt tctctaattt ttcttgataa aattaactat
     1681 tccgaataat taaaatatta agacttttta gattattcga tttattatta agttgtattg
     1741 ctttatatac tgtatatatc actctccttt tttacattca tataatcttt ttaattcaat
     1801 ttaaatttta aatattttgt gtttattata taatctgaaa aaaaagcagt caatagcatt
     1861 tttaattttt ttaattttca aaattatgat tcttaaaaaa tcgttttcct tttatcataa
     1921 cacctattta cgttaattct tgtagtattt tgtatttatt ttgctaaatt gacagttaac
     1981 tttattcaat ttttattcta cttacgtaga tttacctctt gttttttact cttaaaacca
     2041 ttttttctga aaattcctta ttatgattta tcaacttatt tttcttcata acaattactc
     2101 tctaacttcc aacttactta aactttgcag ttgctagtat tcacgtttac atacttatat
     2161 gtcataatta actaaaaatt cttaatatat ctctcaatga aaacaattta ctcatttatt
     2221 taatacattt atataatcat atgtcttaaa ttttgtttta ttattttatt attgtcacaa
     2281 ttttatttat attatatttt tgtaaaaatc atttaatatg tatacttaaa tttataaaat
     2341 tactctaaaa ttctttttta atctctatta ttgttaaaaa ataaaccata tatttttttg
     2401 atattttctt atac
//
LOCUS       DAEPUT010000183         2360 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.189, whole genome shotgun sequence.
ACCESSION   DAEPUT010000183 DAEPUT010000000
VERSION     DAEPUT010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2360
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.189"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            586..1914
                     /locus_tag="KRL22_003855"
     CDS             586..1914
                     /locus_tag="KRL22_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1274274.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIIIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
BASE COUNT          871 a          243 c          384 g          862 t
ORIGIN      
        1 ttttatatta aaaaatatga atgaaaatag tgggttttat aaaaaaacat atttagattt
       61 taacatctca aaggagtttt caaagctaat atttcatttt taaataaaaa aataaaatat
      121 tagttttgat ttctggttta aattgggtta taataaattg tcaaattatt tattaatata
      181 aaatagacta taaaacaagc aaaaatcata ctattatata aaagacctta aagatagaaa
      241 actacagaaa gaagccaaaa tgtttttgaa aaaaatgaaa ttttattgca aaaaaatcaa
      301 aatgaattta acttaatagt tataatctat ttttagtgtt acaaatatac aatgtatatt
      361 atacaatata aaaaatacat ttacttagaa gtattattat atttggattt ttggttttta
      421 taattttttt atatttaaac ataactaaaa ataaaagatt actaaagcta agtagagttt
      481 attttatttt aataaataat aaagctattt ttctatatat tggcataata tatgcttatt
      541 taactatgaa attaaaatta aataggatta atgaggagga aaaaaatggg aagtaatgaa
      601 ctgaaaaaga ctcttggcgt atcagcagca ttatcaactg ttgttggttc cgttatagga
      661 gcgggcgtat tttttaaacc acaagcagtc tatacattaa ctggaggagc tccaggcctt
      721 ggtatattgg catggttaat agctggaatc ataactataa cagctggtct tacagctgca
      781 gaggtatcag ttgcgatacc aaaaactggt ggaatgatgg tatatataaa agaaatttat
      841 ggagaaaaat taggtttttt aactggatgg atgcaaattg tattatttta tccagggatg
      901 atggcagcat taggtgttat atttggagaa caagcatcag cactaattgg tagtccatca
      961 cttttacttc caatagcaat tggaattata ataatagttg cagggcttaa tatgttaggt
     1021 tcaaaaactg gaggagtcat acaaactgtt tctacaattt gtaagttaat accacttatt
     1081 ttaataatgg ttgttggatt tattaaaggt ggtggaaata atccaatact tacacctatg
     1141 gttggtgaag gattaagcct gggtagtgta ctaggtcaag ttttaattgc tatattattt
     1201 gcttttgatg gatggatgaa tgttggtact ttagctggag aaatgaagaa tcctggaaaa
     1261 gaccttccaa aagctataat aggtggattg tcagttgtta tggctgttta ttttataata
     1321 aatttagcgt atctttgggt attaccagct aatgaattag caaattatgc ttctcctgca
     1381 tcagcagttg ctgaagttat atttggttca atgggtggaa aaataatatc tgtaggtata
     1441 ttaatttcag tgtttggagc attaaatgga tttttactaa ctggttcaag ggtggcatat
     1501 actttagcta cagataagac tttaccaaag tatggtatat tttctaaatt aaattctgct
     1561 caagttccag caaatgcaat agcattagta tctgttattg catctatata tgctttgtca
     1621 ggtcaattta atttattaac tgacttagct gtatttgcta cttggatatt ctatgtatta
     1681 acttttatag gggttatgaa acttagaaag actcatccaa atataccaag agagtataaa
     1741 gtcccattat atcctattgt tcctataata gctatagcaa gtggtatatt tgttgtagtt
     1801 aatcaattgt gttttgcagg tatgaaaact actatgatat ctataggagg tcttgtaata
     1861 acagctatag gcttaccagt gtatgcttat atgactagag gagtaaaaag ataaaccaag
     1921 tagtttacaa atgcttcata attaaaataa aagagactgt ctcaaataga gataagtctc
     1981 ttttttattg ttaaaatggt aaagatatgt ttaattttac aaaaaaagag cgttccatga
     2041 actaaaaagt ttattttaag gtattcattt tatttttagt tttttgatta taaaattaaa
     2101 catctaaaaa attatttatt ttaaaatact ttattttaaa gtgtttttta tcaaactaag
     2161 tggtatctgt acaacaaata ttatacatag cttttatgaa aattaaatct ttctgttata
     2221 tataatagaa tattgtatta tatagaaaat attacctgat taatatagtg atttataaat
     2281 gagattagaa aattttattt gataacaaaa attagataat atgaatatat aatgtatgta
     2341 ttaaaaatgt ggcaaatagt
//
LOCUS       DAEPUT010000184         2325 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.190, whole genome shotgun sequence.
ACCESSION   DAEPUT010000184 DAEPUT010000000
VERSION     DAEPUT010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2325
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.190"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..686
                     /locus_tag="KRL22_003856"
     CDS             <1..686
                     /locus_tag="KRL22_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HBH1274275.1"
                     /translation="LMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGE
                     SEETWTTFFEYLKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTT
                     IPKKNSKSFREAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQ
                     YTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYS
                     SRKYINFDK"
     gene            complement(816..2255)
                     /locus_tag="KRL22_003857"
                     /note="aph(2'')-Ia"
     CDS             complement(816..2255)
                     /locus_tag="KRL22_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBH1274276.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(2256..>2325)
                     /locus_tag="KRL22_003858"
     CDS             complement(2256..>2325)
                     /locus_tag="KRL22_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1274277.1"
                     /translation="LGGKNDYKDEIVYVYDYEKGDK"
BASE COUNT          792 a          411 c          240 g          882 t
ORIGIN      
        1 acttaatgac cgatgtactc tatataaaag tacgagaaga aaatcgagta ctctcaaaaa
       61 gctgtcatat agcgattgga ataaccaaag atggcgaccg tgaaattatc ggcttcatga
      121 ttcaaagtgg cgaaagcgaa gagacctgga caacattttt tgaataccta aaagaacgcg
      181 gtttacaagg tacggaactc gttatttctg atgcgcacaa aggattagtc tctgccatta
      241 gaaaatcctt caccaacgta agttggcaaa gatgccaagt tcacttccta agaaatatct
      301 ttaccaccat tcctaaaaaa aattcaaaat ctttcagaga agctgttaaa ggaattttta
      361 agttcacaga tattaactta gcgcgtgagg ctaaaaatcg attgattcat gattatatcg
      421 atcaaccaaa atattcaaaa gcttgcgcat cattggatga tggattcgaa gacgcctttc
      481 aatataccgt acaaggaaat tcccacaatc gactaaagag taccaatcta attgaacgac
      541 tgaatcaaga agtacgcaga agagaaaaga ttattcgcat cttccccaat caaacatcag
      601 ccaatcgctt aattggagcc gttcttatgg acctacatga tgaatggatt tattcttcaa
      661 gaaaatacat caattttgat aagtagaaat ggtaaaaaca ttgtatagca ttttacacag
      721 gagtctggac ttgactcact tcctttatta tttttcattt ttttaaacta tttaatacta
      781 atgtctttta taatagcttt tcatatatta tataatcaat ctttataagt ccttttataa
      841 atttcttttc taccattttc gataaattcc tgtttaatat ttttaattcc ataaacaata
      901 gtttcaatag gataatattc ttcaactata tcttgatatt cttttgcttt ctcaatatct
      961 atatttccat acattcttaa tatatcttct ccaaaatttg ttcctatttc ttcttcacta
     1021 tcttcaagta agtatataaa atcacaatat tcatctataa ttccagaatc tccaaaatca
     1081 attattccag ttaatctatt attgccatct aacaatagat gattacaact aaaatcatta
     1141 tggcataaac actttttacc ctcaaaaact gttgttgcat ttagtctttc cataaaactt
     1201 tctatataat ctttttctat atcagttaaa tcattataaa tagtttcacg caacaatata
     1261 tactcttcta atacattttg tttattatca atagtacatt cactaatatc tgtataatct
     1321 aaaccgtgca tttgtcttaa aaaactggca atatctcgtt ttaacaaatt ttgttcttct
     1381 tctgacatag tagaataaat ttctggtgtt aaaaaagttc ctttaatttc tttataacct
     1441 agtatagata attcatcact aatatacgaa tattcaatat taggaatttt tacattagtt
     1501 tctaaatttg tatttaaaaa attatatatt gctttttctt ttgcataacc ttttttctta
     1561 ttagtactaa attttgtttt aaaaatgtat tcattattaa ctaaatatgc cacactatca
     1621 taaccactac cgattatttc aatactatct actttgaaat tatcaaagta atgctcaatt
     1681 aaatatttca ttgccttaac atttgtggca ttatcatcat atctatattc cattaaataa
     1741 caatcttctt ttttgccctc gtgtaattca tgttctggca aatcttcaat aattctaaaa
     1801 ccagattttt ggtatgccct tattgctctt ggattatttt tatgagggtc taaaataact
     1861 gcattagcat ttctttcttt tttcaaaaat tcaaaaatca atttaatata tcttgtacca
     1921 attcctttac tccaataatt tggctctcct ataaattgat ccataccata gactatctca
     1981 tcagtttttg gataatgata atcagtatat aactcatcat acattttata tatttgtcca
     2041 tatccaatag gaacattgtt atattcaata attactctaa aaacttcatc ttcccaaggc
     2101 tctgtataat gtttttttaa tgattctaat gtatattttt tatctctacc accataaaat
     2161 tctaatactc tttcatcagt taaccatttt aacatcaaag gaaaatcatc atctattaaa
     2221 gttcttatac atatttcatt ttcaactata ttcatttatt tatcaccttt ttcataatca
     2281 tatacatata ctatttcatc tttataatca tttttaccac ctaat
//
LOCUS       DAEPUT010000185         2320 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.191, whole genome shotgun sequence.
ACCESSION   DAEPUT010000185 DAEPUT010000000
VERSION     DAEPUT010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2320
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.191"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(45..1262)
                     /locus_tag="KRL22_003859"
     CDS             complement(45..1262)
                     /locus_tag="KRL22_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HBH1274278.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTTDLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(1453..1866)
                     /locus_tag="KRL22_003860"
     CDS             complement(1453..1866)
                     /locus_tag="KRL22_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1274279.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
BASE COUNT          834 a          346 c          255 g          885 t
ORIGIN      
        1 gattttttag attatatatt ttaatatact ttcttatata agaattattt taaatcaaga
       61 ttatctagta tttttaaaaa tatttttaca gcagtatcca agtcatctac agagacactt
      121 tcattaggat tatgacttac gcccccagcg catcttataa ataccatacc aatatcagtt
      181 atattatcca tttcctgagc atcatggcca gcaccactat aaatataaaa aggattaaga
      241 tttaaatcta taaaactttt ttctatgatt tttgttattt tattagaaca tggtacagga
      301 acattttcaa aagcaagttc acttgtataa ttaagttttc tattttcaca tatatgtgat
      361 atttcattaa atatcttttc tacagaatta tcaagaattt cttgtgaaca agagcgtaca
      421 tcgagtgtaa attctgctct ttcaggtacc acatttgatg aagatggata gaaattcatc
      481 tttcctacag tagcaaccaa atcagtagtc gttttagcta ctttttcgat agctaataca
      541 cattcacagg cacaacatcc agcatcaagt ctcatattca ttggaagtgt accagcatgt
      601 ccagacttac catttactga tatcttaaaa cttttaaatc ctgtaatact tgatacaatt
      661 ccagcaggaa gagattcatt ttctaaaaca ggaccctgct caatatgaaa ttctaaatat
      721 gcatctacat cttttctagg atgcaaattt gttaagtttt ttgtattaaa tccaaacttt
      781 gttacagctt cttcaagtgt aattccattt tcatcaacag atttaagaag ttcctcttta
      841 aaagtaccag caaaaacttt acttcccatt aaagaagttt caaatctagt tccttcctct
      901 tcagcgaaag caattagctt aatattgaaa ggataagacc tattattgtg ttttgcttct
      961 tcaagaccaa ctagaggcac tattatacct aacataccat caaatatacc tccacacttt
     1021 acactatctt gatgagatgc aactactaat gtgggagcat ttggaaagct tgatttatat
     1081 gtacctataa cgtttccaat gtcatcaatt tcaatatcaa gatttaaacc ttccatccat
     1141 gaactaatta aatcaataga ttttttatgt tcttgagtca agataagtct tgtaagacca
     1201 tttgttgttg aacttatttt tcctaatgtt tgtagataat ccatacattt ttttcctaac
     1261 atatttacct cctaaaaata taatttttat ttaagctaag attagctttt atacttataa
     1321 tttttgaact ttcaaataat tttgtatgta tagtaaaata ctattttagt attaataatg
     1381 atataaaaac ataaagtctg tagacgaaga gcagaagttt taatttaaaa atatgaaata
     1441 tgatttttat tattatagta tttttctata ataatatctc tttccagtta gaggataatt
     1501 ttcaagtgaa aatactttat ggtatccaaa tttctcataa aatttaggtg cttgaaaact
     1561 gaatgtatct aaaaaaacat atttacaacc tcgttcttta gcaatttttt cagccttata
     1621 taaaagttga cttccagtac ctttatatct aagcttctca ctaacccata agtattttat
     1681 agaaagccaa ttaccatgag taacacctat aaaacctgca acaattttac ctgctttatc
     1741 tcgaatatat attcctaaat ccactgggtt tttatcttca agtctagcaa gattatattt
     1801 taataatcct tgaaaaatag tatcttcatc ttgtttttct attttttctg taatttctaa
     1861 ttccatattt gaactttctc cttgtataat cttttgtata ttggtatttt ttaataaaat
     1921 cagtagaaag aatatagttt aacattattc taataggcat ttatgctaat gtcaaactaa
     1981 taatacttat tcttaatttt atattgttga tattaaattt ttttaaataa aaatgtagtt
     2041 taagttatat aaaaagaaat catcaataaa tttagtaaac ctaaattgtt gaatattaaa
     2101 ataagttaat ttaatacaaa aaaactattt tagatgttat tctattgcta tgttcaataa
     2161 tatcattagt agttcaattt ataaaatgaa taaattatat aaataagatt agaaagtagt
     2221 aaatagtctt attaaatata agtaataaaa taataaatac ctagtagaga ttaatagtta
     2281 aaaaataaaa tactaccaaa ataaactcga tagtatttta
//
LOCUS       DAEPUT010000186         2234 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.192, whole genome shotgun sequence.
ACCESSION   DAEPUT010000186 DAEPUT010000000
VERSION     DAEPUT010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2234
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.192"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            187..2211
                     /locus_tag="KRL22_003861"
     CDS             187..2211
                     /locus_tag="KRL22_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1274280.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
BASE COUNT          948 a          260 c          309 g          717 t
ORIGIN      
        1 atataaaaag ctattttcct tatcttgcaa aaataatttc aaaataggtt tttataggat
       61 aaaatcctaa aaaaacctat tatttaatca aatatataaa tttatactac tatttgttgt
      121 ataatataac ttgccttata ctttaaatac tttaaaaata aatactattt tgttaggaga
      181 aataaaatgg ataaaaagaa gttaatcctt ataacatatg ataaattgaa tagtgaccac
      241 tacaaagaag aattaacaaa cttttttgga gacgaaataa tcatagaaac acaaaatata
      301 cttgatggaa taaaagaaaa tttagaggga gatgtagtgc tttctctatc acctttaact
      361 agtaattttt taataaaaca ttttaaggaa gatattgaaa ttattcatgg aacgaaagca
      421 ctttcaaaac ttggatatga aaaaatgatg aaactgcctc caggtacaaa atcgttactt
      481 atgacaacca ataaaacttc agcatttgag atggctactt atctatataa aattggtata
      541 aatcatatag attttgtacc gacatatcca gattgtgatg aaatatatga tttagataca
      601 gctataacac caggtcagat tagatttata ccaaaataca taaaaaatat tgttgattta
      661 ggttggagaa aaatctcatt agatacatat atgtcattat tagtagtatt aaaactaaaa
      721 aatgagaaat ttatagaaaa attatacaaa ttgtccaagg agacactaag tcatgatttc
      781 ttaaatacat cattagataa tatatctaaa ttaaaaacta tactttacat gaccattgat
      841 gaaataggtg atggtctaat atttttcaat acctttaata aggttacttt tgtaaataag
      901 tctttactta atatgttgga actagatgaa aaacttataa aatcaccttc cttaatggaa
      961 tatatgccaa agagtttctt agataaaatt acaaagaact taaatataga taatatgatt
     1021 atatacatag acgaaataga taaaaaattc atactttcta aaaaaccatt ttatctttat
     1081 aaaaatatag agggttgctt aattacatta aaagatgtaa acaatataga aatattagaa
     1141 caaaaaataa gaagtgattc tgtcaaaaga ggttatgtag ctaaatataa atttaataat
     1201 attattggaa atagttctat tataaaagat tgtattaaaa aggcaaaaaa aatggctctt
     1261 acagataatc ctatattaat aacaggtgaa acaggaacag gtaaagaagc ctttactcag
     1321 tcaatacaca atcattcaaa tagaaaaaat aaaccttttg tagcaataaa ttgtgcttca
     1381 ttaccaagtg aattacttga aagtgaacta tttggatatg aagatggttc ttttactgga
     1441 gcaaaaaaag gtggaaaaaa aggattattc gaattagctc atactggcac tatattttta
     1501 gatgagatag gagatatgcc acatgattta caggttaaac ttttaagagt cttacaagaa
     1561 aaagaaatta gaaaaattgg tggtacaagt attattccaa ttgatgtgag aatattagct
     1621 gccacaaata aagatttaga gaaattaatt atagaaaata aatttaggat ggatttattt
     1681 tataggataa gtatgttcac tttagattta cctcctctta gaaagagatt agaagatatc
     1741 cctcttcttt tagaatcatt tttaaaagaa cttccctata aaaacataaa actcgataag
     1801 agtcttttag aagctttaaa ttcatacact tggatgggga atattagaga actgagaaat
     1861 tgtgttgaat atatggctta catgggttcc aattatctta caataaatga tttacctcaa
     1921 aacatatctt caaaattaaa taataatcat atgtcaagta atatgtccat attcaatgat
     1981 ttaaaccaat atgacaaaaa catatgcatt tctatcctaa aatcattgca catgaaacca
     2041 atggggagga caaagttaat gaaatttatg gaatataatg tcacagaata cgaagtaaga
     2101 aatatgctag aatatttgac acgcaatgga tacttaattt ctagtaaggg aagaaaaggc
     2161 tcatcaataa ctgagaaagg cataaaaata atagaaaata atataattta aacctatagt
     2221 aattcatctt tact
//
LOCUS       DAEPUT010000187         2177 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.193, whole genome shotgun sequence.
ACCESSION   DAEPUT010000187 DAEPUT010000000
VERSION     DAEPUT010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2177
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.193"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..1899)
                     /locus_tag="KRL22_003862"
     CDS             complement(<1..1899)
                     /locus_tag="KRL22_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein CwpV"
                     /protein_id="HBH1274281.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAEITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAVTVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSGGSSGGSSSSKVGQIKFSATDKQIKMASGDKTVDPSDNTYILKLTNGTVKDGDVKA
                     NVKVAGLPSGLDYTAVGNRSANTITITVSGTASQSIQSDLNNVSVLVKAGAVSGTGAT
                     DSIANTTFE"
BASE COUNT          570 a          395 c          273 g          939 t
ORIGIN      
        1 ttcaaatgtt gtatttgcaa ttgaatctgt agctcctgtt ccagatactg ctcctgcttt
       61 aactagcaca cttacattat ttaaatcact ttgtattgat tggcttgctg ttcctgatac
      121 tgtaattgtt attgtatttg ctgatctatt tcctactgct gtataatcta gtcctgatgg
      181 taatcctgct actttaacat tagcttttac atctccatct tttactgtcc catttgttaa
      241 ttttagtata tatgtgttat ctgatggatc tactgtctta tcacctgatg ccatttttat
      301 ttgtttatct gttgcactaa attttatttg acctaccttt gatgaagaac ttcctccact
      361 acttcctcct gaagaacctc cacttgatga acttcctcct gaagagttag aacttggact
      421 atttccactt attgttggag aattatctcc cttaacacta cttattgtac ctttattatc
      481 tatagtagtc cctttagaat tatttgtaac tgtagttatc ttaccaccat tagtcacttt
      541 tacttgactt gctccagatg ctactgttaa actaccaatc tcacctttag aattattttc
      601 tatcttggct ccatttttat cattaacctt taagttagtt atttttccgt agttaacaaa
      661 agttccatct tttacatcat ctataactac atcatccact tttgcatagt tatttacatc
      721 tccattaggc atgttgatag ttacagtctt tgtatatgta ccatttaagt ttactgttac
      781 tgctttatca gtttgtattg taaatgcttc tttaacctca ctagttggct taaagtttat
      841 aacatcatta gcagtagctt tatctatagc tgattttaat tcagaaattg ttttagcttc
      901 aactgttttt acttcttgta atgacttcat ttcattaaat gctgtctcat taccattccc
      961 accaacttta gttatcttat caaaactctt agagttaact agagattttt gtgaagctga
     1021 taagttcttt ccaactaaaa ctactggtga ttgattttta gcacctaata cacctactgc
     1081 tagtgcatct ataagttggt cttgtttatt cataccatct ttagttacat aagcattttt
     1141 taaatctgtc tttttataaa attcttttat tacttttgca tttgtatcat ttctatctgt
     1201 tccacctagt cttgtactat ttggtagttt atttttaaca gcttcagaaa ttgaactctc
     1261 tccacctact acataagatt gagttatttc agcatccttt ataaatttgt ctgcaactgc
     1321 tgttccattt ttagaatcag caagtattac tggcatattg ttttgtgcag ctggtgctcc
     1381 tacacttaca gcatctgcaa gtcctttttc accattaact acagctattt tcttaacatc
     1441 acttatagca tctaatttct ttgctaattc taaggatgtt tgatatctct cagctccaga
     1501 gattctctca aaagatattt ttaaatcttt tatttctttt tctatatttg tacttaatac
     1561 agaagttcca cctattaagt atactttttt agcttttaat ctttgtattt ctgctttcgt
     1621 cttatcattt aatttatctt tacttgttaa aagtattgga gcattttttg cttttgcaaa
     1681 tggtgttgca gatagagcat ctgctataga tgagtcgttt acgattacta cctcatcagc
     1741 atttttccat ccatcttgac ttattttaac agcagtttca tatctttctt gccctgttaa
     1801 atttgttgcc acagtttgtg cactagctat gcctgctgtt gaacttccag ctatcattgt
     1861 aactgtaagc attgcagcaa tcttctttgg tattttcatt ttattttctt cccccttgtc
     1921 catttgatat tacttaattt tttaactttg ttcccgttct aattctaaag gatacttaat
     1981 atctaatttt aaagaggttt ctaactataa tgatttcata attaatttgt aattattttg
     2041 ttacattgca gtcattatgt aaggaataaa gaaattttct tattgattga aaaatttgta
     2101 aatttatatt ttaaggtaag tttgattttt atgttaatga attgttataa aaaatagggt
     2161 tttgtataaa aaaagta
//
LOCUS       DAEPUT010000188         1895 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.194, whole genome shotgun sequence.
ACCESSION   DAEPUT010000188 DAEPUT010000000
VERSION     DAEPUT010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1895
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.194"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            85..201
                     /gene="rrf"
                     /locus_tag="KRL22_003863"
     rRNA            85..201
                     /gene="rrf"
                     /locus_tag="KRL22_003863"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            208..282
                     /locus_tag="KRL22_003864"
     tRNA            208..282
                     /locus_tag="KRL22_003864"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:240..242,aa:Asn,seq:gtt)
     gene            287..361
                     /locus_tag="KRL22_003865"
     tRNA            287..361
                     /locus_tag="KRL22_003865"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:320..322,aa:Glu,seq:ttc)
     gene            367..442
                     /locus_tag="KRL22_003866"
     tRNA            367..442
                     /locus_tag="KRL22_003866"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Val,seq:tac)
     gene            448..524
                     /locus_tag="KRL22_003867"
     tRNA            448..524
                     /locus_tag="KRL22_003867"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:482..484,aa:Asp,seq:gtc)
     gene            535..609
                     /locus_tag="KRL22_003868"
     tRNA            535..609
                     /locus_tag="KRL22_003868"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:567..569,aa:Thr,seq:tgt)
     gene            624..708
                     /locus_tag="KRL22_003869"
     tRNA            624..708
                     /locus_tag="KRL22_003869"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:658..660,aa:Tyr,seq:gta)
     gene            718..791
                     /locus_tag="KRL22_003870"
     tRNA            718..791
                     /locus_tag="KRL22_003870"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:750..752,aa:Gly,seq:tcc)
     gene            802..878
                     /locus_tag="KRL22_003871"
     tRNA            802..878
                     /locus_tag="KRL22_003871"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:836..838,aa:Arg,seq:tct)
     gene            888..963
                     /locus_tag="KRL22_003872"
     tRNA            888..963
                     /locus_tag="KRL22_003872"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Gln,seq:ttg)
     gene            975..1050
                     /locus_tag="KRL22_003873"
     tRNA            975..1050
                     /locus_tag="KRL22_003873"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1008..1010,aa:Lys,seq:ttt)
     gene            1053..1141
                     /locus_tag="KRL22_003874"
     tRNA            1053..1141
                     /locus_tag="KRL22_003874"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1087..1089,aa:Ser,seq:tga)
     gene            1159..1249
                     /locus_tag="KRL22_003875"
     tRNA            1159..1249
                     /locus_tag="KRL22_003875"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1193..1195,aa:Ser,seq:gct)
     gene            1258..1334
                     /locus_tag="KRL22_003876"
     tRNA            1258..1334
                     /locus_tag="KRL22_003876"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1292..1294,aa:Pro,seq:tgg)
     gene            1420..1495
                     /locus_tag="KRL22_003877"
     tRNA            1420..1495
                     /locus_tag="KRL22_003877"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1453..1455,aa:Trp,seq:cca)
     gene            1556..1632
                     /locus_tag="KRL22_003878"
     tRNA            1556..1632
                     /locus_tag="KRL22_003878"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Pro,seq:tgg)
     gene            1639..1715
                     /locus_tag="KRL22_003879"
     tRNA            1639..1715
                     /locus_tag="KRL22_003879"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1673..1675,aa:Ile,seq:gat)
     gene            1719..1794
                     /locus_tag="KRL22_003880"
     tRNA            1719..1794
                     /locus_tag="KRL22_003880"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1752..1754,aa:Phe,seq:gaa)
     gene            1802..1878
                     /locus_tag="KRL22_003881"
     tRNA            1802..1878
                     /locus_tag="KRL22_003881"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1836..1838,aa:Met,seq:cat)
BASE COUNT          478 a          440 c          516 g          461 t
ORIGIN      
        1 taactctaaa aaaaaataaa aaaagtattg acaaaaatag taaaaaatgt taatattata
       61 cttgtcctag caacaagaaa aaaatgtggt tataatagcg gagaagatac acctgtttcc
      121 attccgaaca cagaagttaa gttctctagc gctgatggta cttggtggga aactacctgg
      181 gagagtagga catagccacg tgaatgttcc aaggtagctc aacggtggag caaccggctg
      241 ttaaccggta ggctgtgggt tcgagcccca cccttggagc cattatggct cgttggtcaa
      301 gaggttaaga caccgccctt tcacggcggt aacaggggtt caattcccct acgagtcacc
      361 atttgtggga tcatagctca gctgggagag cacctgcctt acaagcaggg ggtcacaggt
      421 tcgagccctg ttggtcccac catttgcggc ctggtagttc agttggttag aatgccagcc
      481 tgtcacgctg gaggtcgagg gttcgagccc cttccaggtc gccaaaataa aaatgctggt
      541 gtggctcaac ggtagagcag ctgacttgta atcagcaggt tgtaggttcg attcctatca
      601 ccagctccat gtaaaactaa tacggaggat ttcccgagcg gccaaagggg gcagactgta
      661 aatctgttgt catcgacttc ggtggttcga atccaccatc ctccaccaat taaatatgcg
      721 ggtgtagctc aatggtagag ttctggcctt ccaagccagc tgtgagggtt cgatcccctt
      781 cacccgctcc aaagaaagcg tgggtgcata gctcagctgg atagagcaac gcccttctaa
      841 ggcgtgtgtc cggggttcga atccctgtgc gctcaccaca tatatattgg ggattagcca
      901 agtcggtaag gcacatgact ttgactcatg tatgcgtagg ttcgagtcct gcatccccag
      961 ccaaataaaa atatggtcta ttagctcagt cggtagagca cctgactttt aatcagggtg
     1021 tcccgcgttc gagtcgcgga tagatcacca atggagaggt gtccgagtgg tttaaggagc
     1081 tggtcttgaa aaccagtgac ttcgaaaggg gccgtgggtt cgaatcccac cctctccgcc
     1141 aaaaaaatga ctgaatttgg agaagtactc aagtggctca agaggatccc ctgctaaggg
     1201 attaggctgg gtaaccggtg cgagggttcg aatccctcct tctccgccat tcaaaaacga
     1261 ggtgtagcgc agtttggtag cgcacatggt ttgggaccat ggggccgggg gttcgagtcc
     1321 cttcacctcg accaacttaa gcttttagtt cagttggtta gagtgcccaa ctcatggcta
     1381 gtaattctag ggtttgagtc catgaaggtt attcttcata ggggtgtagc tcagttggta
     1441 gagcgtcggt ctccaaaacc gtgcgccggg ggttcgagtc cctccacccc tgccaaataa
     1501 aaaggacttg aaaaaagttg gattttagag tagtataaga tagtaaataa gatttcgagg
     1561 tgtagcgcag tttggtagcg cacatggttt gggaccatgg ggccgggggt tcgagtccct
     1621 tcacctcgac caagaaaagg gcctatagct caggtggtta gagcgcacgc ctgataagcg
     1681 tgaggtcgct ggttcgagtc cagctaggcc caccatttgc ccagatagct cagtcggtag
     1741 agcaggggac tgaaaatccc cgtgtcggtg gttcgattcc gcctctgggc accaggaata
     1801 cggcggtata gcttagttgg ctagagcgtt cggttcatac ccgaaaggtc ataggttcga
     1861 ctcctattac cgctaccatc taactatatc aataa
//
LOCUS       DAEPUT010000189         1844 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.195, whole genome shotgun sequence.
ACCESSION   DAEPUT010000189 DAEPUT010000000
VERSION     DAEPUT010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1844
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.195"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            442..909
                     /locus_tag="KRL22_003882"
     CDS             442..909
                     /locus_tag="KRL22_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1274282.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDIGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          759 a          112 c          257 g          716 t
ORIGIN      
        1 acaaaatatc aataattaga aagattatga aaactaaatt agaagaacta aaaactatat
       61 ttttattaat tataatattt gaataatctt tttaatcata taaaatgcat atacttgtaa
      121 tatttaaagg tgatattaat attattagtg tatattaata ttcccttgaa attaaaaaaa
      181 catagatatt tcagtaatct aaaatagtct acaaaaataa tagttttatc aaaattaata
      241 agaatacata tagatttaaa cctaaaagta tgaacatgtc tgttttttac aagattaaaa
      301 tttatattat atgataaaat taacttaact atttcaataa gacttataat ttttttcttt
      361 atactagacc ttattgaaac ctttatagtt taattctaat tatatattat aaataaagta
      421 tgtgtatatt aaggaggtaa tatgaagttt ttaaatgttt taatagtagt tgaagatatt
      481 gagaaatcaa aaaagtttta ttatgatgtt ttggggttaa aggtaatctg tgattttgga
      541 gaaaatgttg tattagaagg taatatatca ttacaagaaa aaaagctttg gttagaattt
      601 attaataaga gtgacagtga agttaagttc aatggaaatg atgctgagtt atattttgag
      661 gaagataatt ttgatacttt tgttgaaaga ttgagtacaa tgaaagatat agattatgtt
      721 catctagcta tagagcatag gtggggtcaa agagcaatta gattttatga tttagatggg
      781 catattattg aggttggaga aactatgtca tctgtgtgta gacgtttttt agatattggt
      841 ctttcaatag atgaggtagc taaaagaatg gatgtaactg tcgaatatat tgaatcagtt
      901 ttagaataga tggattatat taaagtaaaa ctatattttg tatagaagta agggctgtaa
      961 gtaaacttgt atggaaacaa atttacttac agtttttgtt tttgtaagat acagaatata
     1021 atatttgtta taattttatt tggattttta aaaagtgcat gattttcctt acatattata
     1081 atagaattta atatttattg gatgatttaa atttagaaaa atataagtat tagcttataa
     1141 aagataatta tacttactat caagctgtag aatcatatat actattttat gtaattatgt
     1201 taaaatttaa ttgaacaaat taaaaatata gtgaaaattg tagttttagt ttatttattt
     1261 aataaatatt tcaaataaaa taatgtttaa ataagaaaca taaataataa tattattatt
     1321 gttcttaaag acaaaaaatc ttagcttaaa aatttgtatc atataaaatc cctacatatt
     1381 atggaagtaa tgatacatta tatgatatac acaataaagt ataaaagtat ttacatgttt
     1441 tttctatata ttttataagt tttaggtatg gaaaattact aaataaaaat tagattaatg
     1501 attatgatag tatagataaa gtttattctt tttattaata gaaattgttg tataaaaata
     1561 ataaaagtga ggagagtgat atttaaataa aaaaatttta ataagtattg gtaatatagt
     1621 ttttagggat gattatttta tgtaaaaagt tgttatttgt aaagataaat atagaaaata
     1681 ttataagtat tgatttagtg ataatctaaa aggtgagaat tgtaataaaa agagaacata
     1741 tccttcaaat ggatgtaaac ttataaataa cattattaca agagatttat tatacatata
     1801 ctgcaactat taattagaat ttatactgta tttgtattta aata
//
LOCUS       DAEPUT010000190         1842 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.196, whole genome shotgun sequence.
ACCESSION   DAEPUT010000190 DAEPUT010000000
VERSION     DAEPUT010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1842
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.196"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(63..533)
                     /locus_tag="KRL22_003883"
                     /pseudo
     CDS             complement(63..533)
                     /locus_tag="KRL22_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            complement(536..994)
                     /locus_tag="KRL22_003884"
     CDS             complement(536..994)
                     /locus_tag="KRL22_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274283.1"
                     /translation="MSYEYQNIYQKARENTNLTQEKASELLDISVESLRAYENDKRIP
                     NNQIVAKMVSIYNNNLLGYEHVRRTTEAGVMFLPKLEMKSLSSITLKLHKEIKDYLKK
                     EDDFIDIVEDDVIDEDEEEVWNDVMKKLEGIYEAILKLKLSRNTKISKEV"
     gene            complement(1027..1218)
                     /locus_tag="KRL22_003885"
     CDS             complement(1027..1218)
                     /locus_tag="KRL22_003885"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274284.1"
                     /translation="MNKKCLPKWSKEVKKAMIDRDLKLDDLSEELGLSKYHLSAVIND
                     RLKSPNAKEAICKYLKVKG"
     gene            1384..1725
                     /locus_tag="KRL22_003886"
     CDS             1384..1725
                     /locus_tag="KRL22_003886"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274285.1"
                     /translation="MLYERLEKICKQNNITISALCKEITGSTGNLSTWKKNNIKSEYL
                     ANICIKFNISADYLLFGEQQNSNTKTLFSENEKEILSLLHKFNERNQIKFISKVEDLA
                     DKMLEKENNTD"
BASE COUNT          546 a          294 c          211 g          791 t
ORIGIN      
        1 tttgctaatt ctccaactag gattgaatta tcagaagatg ctaccgaatc agcaaaaagt
       61 acttttggtt gctgtaactg aattacctta tctttttctt gattttctaa ttgtagttgt
      121 tctttttcct caacttctat taacaactgt tgcaatgctt ctttatatgt agttggtaac
      181 tttggttgct gttcttttaa tatttgttcc atttcattaa atcttttagt atatatcccc
      241 gtaaatgcag taccctttat tcctgtcatt ttatttgcta taaagtcaca acctattttt
      301 gttattgcat agcatggctt ctctctttta taatcatcta aataagtatt ttcaataaaa
      361 taatcagatg ggtacaaatc tgtactcatg tttttgttag cttcttccat ctggtttata
      421 taatttctta tatctcttaa taaaatcttg tgttcttttt caaccattaa agctatatct
      481 ctgctatcag ttgttagttt attgttaact tttgctattg ttaaatcttt catatttata
      541 cctcctttga tatttttgta ttccttgaaa gttttaattt taaaatagct tcatatatac
      601 cttctaactt tttcataaca tcattccaaa cttcttcctc atcttcatct attacatcat
      661 cttcaactat gtctataaaa tcatcttcct tttttagata atctttgatt tctttatgta
      721 atttcaaagt tatacttgaa agacttttca tttctagctt tggtaagaac attactcctg
      781 cttctgtagt ccttctcaca tgctcatagc ccagtaaatt attattatat atagatacca
      841 tctttgctac tatttgattg tttggtatcc tcttgtcgtt ctcatatgct cttaaactct
      901 ctacagatat gtccagtaac tctgatgctt tttcctgtgt taaattggta ttttctcttg
      961 ctttttgata aatattttgg tactcatatg acattcaaat cacctctttg aaaggttata
     1021 ctataactaa ccttttactt ttaaatactt acaaattgct tcttttgcat ttggactttt
     1081 tagtctatcg ttaattactg ctgatagatg atattttgat aaccctaatt cctctgataa
     1141 atcatctagt ttcaaatctc tatctatcat ggctttttta acttccttgc tccattttgg
     1201 taaacatttt ttattcatta ttatcacctt ctttattagt gtgtttattt gtggtaaaat
     1261 taagtttgta taacaatttg ttgtcttaag taattgttat tatagttata ttatattgca
     1321 aatatttgca tatgtcaata tatttattgc aatatttcgc aattattttt caggaggtat
     1381 tttgtgttat atgaaagatt agaaaaaata tgtaaacaaa ataatattac tatatcagct
     1441 ctttgcaaag aaatcactgg tagtactgga aatctatcaa cttggaaaaa aaataatatc
     1501 aaatctgaat accttgcaaa tatttgcata aaattcaata tttcagctga ttatttactt
     1561 tttggagaac aacaaaattc caatacaaaa acattatttt cagaaaatga aaaagagatt
     1621 ttatctctat tacataaatt caatgagcgt aatcaaatta aatttataag taaggttgag
     1681 gatttagctg acaaaatgtt agaaaaagaa aataatacag attaactact atatgcctgc
     1741 ttctaatctt taggcaggcg tattgttgtt tgctctcttt gcatctaatc acctcttttg
     1801 aatattctgt atttagtttt caaagtgcta ttaatcttta ac
//
LOCUS       DAEPUT010000191         1837 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.197, whole genome shotgun sequence.
ACCESSION   DAEPUT010000191 DAEPUT010000000
VERSION     DAEPUT010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1837
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.197"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            151..1749
                     /locus_tag="KRL22_003887"
     CDS             151..1749
                     /locus_tag="KRL22_003887"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HBH1274286.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDIDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILSVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
BASE COUNT          708 a          219 c          278 g          632 t
ORIGIN      
        1 atattaaatt tgtagtattt atgtaagaaa taaattttat ataatatttt ttcactaaat
       61 ttttttcttt ttacaacaaa tactcactac cttttgatat aatattttta tcaattatta
      121 ttatattcaa gttttgaaag gagtattaaa atgagtttat tagttttcgg acataaaaat
      181 ccagatacag attcaatatg ttctgcaatt tcattagcac atttaaagaa caaactagga
      241 ataaaagcaa cagcttatgc tttaggagat atcagaaaag aagctaaata tgccttggat
      301 tactttaagg tagatgcacc tgaaatttta gataatgtta gaatacaagt tagagattta
      361 aattatgata aagtagtacc tttaacacca acttcatcta tattagaggc ttataacctt
      421 atggatgaaa aaaatgttaa aacactacct gtaacttatg atgatggaac ttttgctggt
      481 atcattacta tgaaagaaat agctaaaaat ctacttcatc aacactttac aactatacac
      541 acatcactat caaacatttg taaaaacctt aatggtacta ttcttgtgga ctgtggtgaa
      601 gatataaaag gtagagtagt cactttatca tttggaatgg agactctaat agagacttta
      661 aaagaaggag acatagctat tgttggagat agatatgata gtattgaata tgctattgat
      721 acaaaagtta aacttttaat acttactaat catacagaga tttcaaaaga tttgctagct
      781 cttgctaaga taaatggagt gtctgttgtt tctgttgaaa gtgacaatta taaaacttct
      841 aatgtaataa atcaatgtag tttcttagac tctatagaag ctacagaaaa tttaattaca
      901 ttcaaagaag atgattatat ggatgaaata aaagagatta tgctagaaac aaacttcaga
      961 tcttatccaa tattagatga tgataataag tttttaggtt tagtttcaaa aggtcatcta
     1021 ttaaacccat ctaaaaagaa tgttgtttta gttgaccata acgaatatgc tcaaagtgct
     1081 gatggaattg aacaagcaaa catagttgaa ataattgacc atcataaact tggtggtatt
     1141 tctactgatg ttcctatgtc atttagagtt atgcctgttg gatgcaatag tactataatt
     1201 tatcaaatgt acaaagaaaa taatgttgag ataccttatg aaatagccgg gcttctttta
     1261 tctgctatat tatcagatac attattattt aagtctccaa caacaactga tatagataag
     1321 aaagcttgtg aagaattaag taaaatagca aaagtagaca tggaaaaata cgctatggat
     1381 atgtttaaat gcggtacttc tttagatgaa tatactatag aagaaatagt aaatatggac
     1441 tttaaagaat ttaatatgag tggacataga gttggtattg gacaagtatt taccttagac
     1501 atagactcta tatttgctaa aaaagatgag tttttatctt atataaattc gactgattat
     1561 gataaattaa ttctttcagt tacagatata atcaaagaag gttcttattt aatctataaa
     1621 gcagaagata gcttaattgc taacgcattt ggtgttgaag gtgttcaagg cacatttgca
     1681 ccaggtgttg tatcaagaaa aaaacaatta gtccctaatt taactactgc aatcaaaaat
     1741 tttaaataat ataaaatttt taaataacga aaactgtctc aaatctatat ttgagacagt
     1801 tttttattat atatatattg ataataaagt taaataa
//
LOCUS       DAEPUT010000192         1808 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.198, whole genome shotgun sequence.
ACCESSION   DAEPUT010000192 DAEPUT010000000
VERSION     DAEPUT010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1808
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.198"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            162..1211
                     /locus_tag="KRL22_003888"
     CDS             162..1211
                     /locus_tag="KRL22_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1274287.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            complement(1361..1708)
                     /locus_tag="KRL22_003889"
     CDS             complement(1361..1708)
                     /locus_tag="KRL22_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH1274288.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
BASE COUNT          670 a          248 c          281 g          609 t
ORIGIN      
        1 atttattcaa tattacacat tactgaaaaa actaaacata aaactgaaaa ttattattaa
       61 gtttttgtag aaatattata agtatagata catttttgta acaactacaa taaatattta
      121 atactatata ctattcgtat gtcttatggg aggtatttat tatgtttaaa aaaatagtcg
      181 caatagcaag ctctatcatt gtaagtacaa tatgtctaac tggatgtgat tttaactcta
      241 atgacaaaaa agatgaatct tcttcgtcta aaaatctgga taaagtaact atagcagaag
      301 ttactcactc tgttttttat gctccacagt atgctgctat tacgaaagga ttctttgaag
      361 atgaaggtat aaagattgac cttataaata cccaaggtgc agataaaact atggcagctt
      421 tgatttcagg tgaagcaaac gtaggtttaa tgggtcctga agcatctata tatgtatata
      481 atcaaaacaa aaacgattat gcagtgaact ttgctcaatt gacaaaaaga gatggtagtt
      541 ttctagttgc taggaaaaaa atgcctaatt tctcttacaa tgatttaaaa ggaaccgaaa
      601 tattaggtgg tagaaaaggt ggagttccac taatgacttt tgaatatgtt ctaaaagaaa
      661 aaggtcttac tattggagaa aatctaaaag caggcaatgt taatgtaaga actgatgtac
      721 aatttggtgt aatggctgga gcttttgcag gtggagaggg tgactttaca acagcatttg
      781 aacctacagc aacagcaatg gaaaaagaag gtagtggata tatagttaca tctataggaa
      841 aagattctgg agaaatacct tttacagcat actctactac gagatcatac atgaaaaaca
      901 ataaagattt aattcaaaga tttacaaacg ctgtttataa aggtcaatta tggattcaac
      961 aagcatctag caaagaagta gctaaggcta tgcaaccttt ctttgaagat atatctttag
     1021 aagatttaac aacagttgta gatagatata aatcaataga tgcatggtct caaaatcctg
     1081 tattaaaaga ggaaggtttg aagaaattga tgactgttat gaaagaagct aaagaactag
     1141 ataaggaagc accttataaa gatatcgtaa atactgagtt tgcaaacaat gctataaaaa
     1201 atattaaata aaatatatta gttttagcta gatattttct tgtttttata atgaaaatta
     1261 acaaaaatat aaaaagagcc ttttaaaaga ctctttttat atttgagatt aaagtttata
     1321 taataaaata gatattaaag tactaactgt acttatatat ctatcctctg tattctgctc
     1381 cagcattaat ttttgtaatt tgaacggcta ccatttcttc attgcttcca ttagtaattt
     1441 catgccactc tcctgttggt acaaatacag tatcgccgtt ttttacatca cattcatgct
     1501 caccaagttt cattttacct tctcctttta ggaacacaaa tatttgttca ccattagggt
     1561 gtctatgagc attaagaact tgattaggtt taaaataata aacttctgaa gttatatcgt
     1621 taccagcaaa tactggtatt tttggaactg ctgtatcatt atattgagct aagcttccgt
     1681 ctaatagatt ctttttattt tcatgcatac tagaaatacc tcttttctat attatagatt
     1741 tactattatt ataccaatat aagaaaatag tattctcact ttacacaata ggaataaaat
     1801 tcttttat
//
LOCUS       DAEPUT010000193         1761 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.199, whole genome shotgun sequence.
ACCESSION   DAEPUT010000193 DAEPUT010000000
VERSION     DAEPUT010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1761
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.199"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            305..1576
                     /gene="serS"
                     /locus_tag="KRL22_003890"
     CDS             305..1576
                     /gene="serS"
                     /locus_tag="KRL22_003890"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH1274289.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRAYMGVSVIK"
BASE COUNT          758 a          173 c          313 g          517 t
ORIGIN      
        1 aaatttatat aaaagttaat aactatacaa gattgataaa gaaaaagtca aaatagataa
       61 ttgattagca aaatagatat aattataatg aagttaaatc tagcaatatt ctcctaaaat
      121 taaatttcat ttatttaatt aaatataatt tgacaatggg caaaaaagtg agtaaaatat
      181 aaataaaata aaaataacag gttcggataa agagaaaggt ttcttaacct caagcataaa
      241 gtatattatc taagttattt gagattaaga gataaatcca atcttaggta ctgaggagga
      301 aaaaatgctt gatataaaaa gaataagaga aaatttagat tgtataaaaa aagcaatgga
      361 aagaaggggc gaaaaagact ttaaccttga tgaagtagtt aagttagatg atgaaagaag
      421 aaagattctt caagaagttg aagttatgaa aaatgaatta aatacagcat ctaaaaacat
      481 accaaatctt ataaaagaag gtaaagatgt agaaaatgaa aagattaaac taaaagagtt
      541 atctgataaa attaaggtaa tagaccaaaa tcttaaagaa gtagaagata agatggaata
      601 cctattaatg agaataccaa atgtaccaca tccagaagta ccacaaggtg aaactgatga
      661 agataatgtt gaagtaagaa cttggggaaa gactactacc tttgattttg aatctaaggc
      721 tcattgggaa attggaacag aattaggtat acttgatttt gaaacagcta gtaaaataac
      781 tggttcaaga tttactcttt acaaaggatt aggtgctaga ttagagagag cattattaaa
      841 tttttactta gacacgaata caaaagtaaa tggatataca gaagttattc caccatttat
      901 ggcaaataga aatagttttt taggtacagg acagttacct aagtttgaag aagatatgtt
      961 taaaatagaa ggtctggact attttatgat tccaacatca gaagttcctt taactaatat
     1021 acatgctaat gaaatactta aatttgaaca attaccaata aattatacag cttatactcc
     1081 atgttttagg tcagaagctg gttctgctgg aagagataca agaggtttag taagacagca
     1141 tcagtttaac aaagtagaaa tggttaaaat agttgcacca gaagaatctt acaatgagtt
     1201 agaaaagctt actaacaatg cggaaactat gctacaatta ttgaatctgc cttatagagt
     1261 agtaaagata tgtacgggtg atttaggatt tacggcttct tttaaatatg atgtagaagt
     1321 ttggatgcca agttacaata ggtatgttga gatttcatct tgttcaaact gcgaagattt
     1381 ccaagctaga agagcaggaa taagatttaa aagagataaa gattctaaag ctgaatatgt
     1441 acacacatta aatggctctg ggttagctat tggaagaagt gttgcagcta tattagaaaa
     1501 ttatcaacaa gaagatggtt ctgtggttgt tcctgaagtt ttaagagcat atatgggagt
     1561 ttctgttatt aaataagagt taaattatgt atttttaagc aatacaataa tatagaggta
     1621 ataaaaaata attaatataa aagtgatact tctaatatag aagtaataaa aaaatagtta
     1681 atgtaaaagt gatacaataa tatagaagta ataaaaaata gttaatgtaa aagtgataca
     1741 ataatataga agtaataaaa a
//
LOCUS       DAEPUT010000194         1669 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.200, whole genome shotgun sequence.
ACCESSION   DAEPUT010000194 DAEPUT010000000
VERSION     DAEPUT010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1669
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.200"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..348
                     /locus_tag="KRL22_003891"
     CDS             <1..348
                     /locus_tag="KRL22_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBH1274290.1"
                     /translation="EIPGQGKVQGLNRPRDGGYYDDALMPTTRNKRDVWLINTVPYKG
                     AHFAAFPPKLAETCILAGCPKGGIVIDPFFGSGTTGFAAKSLDRHYIGIELNAEYCAL
                     ARARIGGAGLSNN"
     gene            375..>1669
                     /locus_tag="KRL22_003892"
     CDS             375..>1669
                     /locus_tag="KRL22_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBH1274291.1"
                     /translation="MTRDGVVEVNETQQTAERISSREADSDFSQPDSAAAERVIEHLD
                     AAHTRKANKKVVKKEQEATALRTSTSRLQFTEEELAAPELERYIEKSNKAADRLDAAK
                     AAIPKQKKLVKERTFDEATGKAKTRLLFEKQEKPIPGGKKGNPLSRPAQEAGIFVHNK
                     IHSVEKDNSGVEGAHKSEELAERGAKYGARKLKQGYRSHKLKPYREAAKAEKAAFKAN
                     VNFQYHKTLHDNPQLTSNPLSRFMQKQQIKRQYAKAAKKGGAKAAAEATRKTAKKTAE
                     ETRKAAAFAARHPAGILIAVAALLLFIMISAGLSSCGAMFSGLTNGVLGTSYTSEDSD
                     LLAVENNYAALENGLQSEIDNIENTHLGYDEYRYDLDSIGHNPHELASYLTALLQSYT
                     PQSAQAELERIFAMQYTLTLTEEVEIRYRTETSTDPETG"
BASE COUNT          499 a          439 c          443 g          288 t
ORIGIN      
        1 gaaatacccg gacaaggaaa ggtgcaggga ctaaaccgac cgcgggacgg tggctactat
       61 gacgacgcgc tcatgccgac cacgcggaac aagcgggacg tgtggctgat taacactgtc
      121 ccatataaag gggcgcattt tgcagctttt cccccaaaat tagcggaaac ctgtatcttg
      181 gcgggctgtc ccaaaggtgg gattgtcata gacccgtttt tcggaagcgg aaccacagga
      241 tttgcagcaa aaagccttga ccgccattat atcgggattg aattaaatgc agagtattgc
      301 gcccttgcga gggcgcggat tggaggtgca ggactatcaa acaattaaaa ccacgcgata
      361 aaatcacaca gaaaatgacc cgcgacggcg tggtggaagt caacgaaaca cagcagaccg
      421 ccgagcgtat cagcagccgg gaagcagaca gcgacttttc acagccggac agtgccgcag
      481 cggaacgcgt catagaacat cttgacgcag cacatacccg aaaggcaaac aaaaaggtag
      541 tcaaaaaaga gcaggaagct actgctttgc gtacttccac ttcccgcttg cagtttaccg
      601 aggaagaact tgccgccccg gaactggaac gctatattga gaaatcaaac aaagccgctg
      661 accgactgga cgcggcaaag gcagctatcc caaagcaaaa gaaactggtt aaggagcgca
      721 cctttgatga agccacagga aaagcaaaga cccgcttact ctttgaaaaa caggaaaaac
      781 cgatacccgg cggcaaaaag ggaaacccgc tgtcccgccc tgcacaggaa gcggggattt
      841 tcgtccacaa caagatacat tcggttgaaa aagacaattc cggcgttgag ggggcgcata
      901 agtcggagga acttgccgag cgcggcgcga aatacggggc gcggaagtta aaacagggct
      961 accgcagcca taagctgaaa ccctaccggg aagcagcgaa ggcagaaaag gcagcattta
     1021 aggcaaacgt caacttccag tatcacaaga ccctgcacga caacccgcag cttacctcta
     1081 acccgctttc ccgtttcatg cagaaacagc agataaaacg ccagtatgca aaggcggcaa
     1141 agaaaggagg ggcaaaagcc gcagcggaag ccacaagaaa gacggcgaag aaaaccgccg
     1201 aggaaacgag gaaagccgcc gcatttgcgg caagacaccc ggcgggcatt ttgattgcag
     1261 ttgccgcgct gcttctcttt attatgattt ccgcagggct gtcctcttgc ggggctatgt
     1321 tttcgggctt gactaatggc gtgcttggca cttcctacac gtccgaggac agcgaccttt
     1381 tggcagttga aaacaactat gctgcattgg aaaacgggct gcaaagtgag attgacaata
     1441 tcgaaaacac ccacctcggc tatgatgaat accgctatga ccttgacagt atcggacata
     1501 acccacatga acttgcgtct tacttgaccg ccctcttgca gagctacacc ccgcagagcg
     1561 cacaggcaga gcttgaacgt atctttgcca tgcagtacac cttgacgctg accgaggagg
     1621 ttgaaatacg ttaccgcacc gaaacaagca ccgacccaga aaccgggga
//
LOCUS       DAEPUT010000195         1669 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.201, whole genome shotgun sequence.
ACCESSION   DAEPUT010000195 DAEPUT010000000
VERSION     DAEPUT010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1669
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.201"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..348
                     /locus_tag="KRL22_003893"
     CDS             <1..348
                     /locus_tag="KRL22_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBH1274292.1"
                     /translation="EIPGQGKVQGLNRPRDSGYYDDALMPTTRNKRDVWLINTVPYKG
                     AHFAAFPPKLAETCILAGCPKGGIVIDPFFGSGTTGFAAKSLDRHYIGIELNAEYCAL
                     ARARIGGAGLSSN"
     gene            375..>1669
                     /locus_tag="KRL22_003894"
     CDS             375..>1669
                     /locus_tag="KRL22_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBH1274293.1"
                     /translation="MTRDGLIEVNETQQTAERISSREADSDFSQPDSAAAERVIEHLD
                     AAHTRKENKKEVKKEQEATALRTSTSRLQFTDEERATPELETYIKKSEKAADRLDAAK
                     AAIPKQKKLVKERTFDEATGKAKTRLRFEEQEKPVPGGKKGNPLSRPAQEAGIFVHNK
                     IHSVEKDNSGVEGAHKSEELAERGAKYGARKLKQGYRSHKLKPYREAAKAEKAAFKAN
                     VNFQYHKTLHDNPQLTSNPLSRFMQKQQIKRQYAKAAKKGGAKAAAEATRKTAKKTAE
                     ETRKAAAFAARHPAGVLIAVAALLLFIMISAGLSSCGAMFSGLTNGVLGTSYTSEDSD
                     LVATEQNYAAMENALQSEIDAIESTHPDYDEYRYDLDSIGHNPHELASYLTALLQSYT
                     PQSAQAELERIFAMQYTLTLTEEVEIRYRTETSTDPETG"
BASE COUNT          503 a          443 c          446 g          277 t
ORIGIN      
        1 gaaatccccg gacagggaaa ggtacaggga ctaaaccgac cgcgggacag cggctactat
       61 gacgacgcgc tcatgccgac tacgcggaac aagcgggacg tgtggctgat taacactgtc
      121 ccatataaag gggcgcattt tgcagctttt cccccgaaat tagcggaaac ctgtatcttg
      181 gcgggctgtc ccaaaggtgg gattgtcata gacccgtttt tcggaagcgg aaccacagga
      241 tttgcagcaa aaagccttga ccgccattat atcgggattg aattaaatgc agagtattgc
      301 gcccttgcga gggcgcggat tggaggtgca ggactatcaa gcaattaaaa ccacgcgata
      361 aaatcacaca gaaaatgacc cgcgacgggc ttatcgaggt aaacgaaaca cagcagaccg
      421 ccgagcgtat cagcagccgg gaagcagaca gcgacttttc acagccggac agtgccgcag
      481 cggaacgcgt catagaacat cttgacgcag cacatacccg aaaggaaaac aaaaaggaag
      541 tcaaaaaaga gcaggaagct actgctttgc gtacttccac ttcccgctta cagtttaccg
      601 acgaggaacg ggcaacgccg gaactggaaa cttatatcaa aaaatcggaa aaagccgctg
      661 accgactgga cgcggcaaag gcagctatcc cgaagcaaaa gaaactggtt aaggagcgca
      721 cctttgacga agccacaggc aaggcaaaga cccgcttacg ctttgaagaa caggaaaaac
      781 cggtacccgg cggcaaaaag ggaaaccctc tgtcccgccc cgcacaggaa gcggggattt
      841 tcgtccacaa caagatacat tcggttgaaa aggacaattc cggcgtggag ggagcgcata
      901 aatcggagga acttgccgag cgcggcgcga aatacggggc gaggaagtta aaacagggct
      961 accgcagcca taagctgaaa ccatacaggg aagcagcaaa ggcagaaaag gcagcattta
     1021 aggcaaacgt caacttccag tatcacaaga ccctgcacga caacccgcag cttacttcta
     1081 acccgctttc ccgtttcatg cagaaacagc agataaaacg ccagtatgca aaggcggcaa
     1141 agaaaggagg ggcaaaagcc gcagcggaag ccacaagaaa gacagcgaag aaaaccgccg
     1201 aggaaacaag gaaagccgcc gcatttgcgg caagacaccc ggcgggtgtt ttgattgcag
     1261 ttgccgcgct gcttctcttt attatgattt ccgcagggct gtcctcttgc ggggctatgt
     1321 tttccggctt gactaacggt gtgcttggca cttcctacac gtccgaggac agcgaccttg
     1381 tggcaacgga acaaaactac gccgctatgg aaaatgccct gcaaagtgaa attgacgcta
     1441 tcgaaagcac ccaccccgac tatgatgaat accgctatga ccttgacagt atcgggcata
     1501 acccccacga attagcgtcg tacttgaccg cccttttgca gagctacacc ccgcagagcg
     1561 cacaggcaga gcttgaacgt atctttgcca tgcagtacac cttgacgctg accgaggaag
     1621 tggagatacg ctaccgcacc gaaacaagca ccgacccgga aaccgggga
//
LOCUS       DAEPUT010000196         1564 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.202, whole genome shotgun sequence.
ACCESSION   DAEPUT010000196 DAEPUT010000000
VERSION     DAEPUT010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1564
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.202"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            178..1239
                     /locus_tag="KRL22_003895"
     CDS             178..1239
                     /locus_tag="KRL22_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBH1274294.1"
                     /translation="MRDFLKNYKSSIILLACTIVGAIVGLVLGPKASILKPFGDLFIN
                     ALLMIVVPLVFLSVSSGVASIKNMERFGKIMKGTAIVFMGTTLVIAFLGITSALLFNP
                     SKGLDVSSVKNLMVAQDAETLESKGTLLDQVVSSITVKNFGDLFSSSNLLQLVIFAVL
                     IGTAIAMMGDRGNTIRKLLSEGTEAILKVVSIFMLYAPIGLGCYTATIIGELGSKIIQ
                     GYVRVFVIYSLTAAMYFLLFYSLYAFLSAGKQGFRQFWRNAIKPIATALATSSSSACI
                     PSNLEASKNIGVPDDISETVIPLGINIHKDGSVLAVIIKVAFLSGILGSGMANPATIG
                     QLFITVFVVGVFMAPVAGG"
     gene            1252..1449
                     /locus_tag="KRL22_003896"
     CDS             1252..1449
                     /locus_tag="KRL22_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBH1274295.1"
                     /translation="MLVVSIFGFPVEAIPLLTVITTITDIPNTILNTTGNTVSSMLVS
                     RLVEGKDWLIDKTAITTKKIS"
BASE COUNT          577 a          181 c          275 g          531 t
ORIGIN      
        1 ttaataaaac gtttaaaaat acaaaaaaac tatagaaatt gacatatatt ccagtatttg
       61 ctaaaatagc tgttggggaa aattacaaaa attattaatg cgcattagat aatttacttt
      121 aattttttta gcatttgggg taatttataa tataaagcat tagaaaggaa aatataaatg
      181 agggactttt taaaaaatta taagtcatca attatacttt tagcatgtac tatagtaggg
      241 gcgatagtag gattagtact tggtccaaaa gcttcaatac taaaaccatt tggagattta
      301 ttcataaatg ctctattaat gatagtagta ccattagttt ttcttagtgt ttcttcaggt
      361 gttgctagta taaaaaatat ggaacgattt ggaaaaataa tgaagggtac agctatagta
      421 tttatgggaa caacacttgt aattgcattt ttaggtatta catctgcatt attatttaat
      481 ccgtctaaag gattagatgt atcaagtgta aaaaatttaa tggtggctca agatgcagaa
      541 actttagaat caaaaggaac gttattagac caagtagtat caagtattac agttaaaaat
      601 tttggagatt tattttccag tagtaattta ctacaattag ttatatttgc agttttaatt
      661 ggaacagcaa tagctatgat gggagatagg ggaaatacaa taagaaagct tttatcagaa
      721 ggaacggaag caatattaaa agtagtaagt atattcatgc tttatgctcc tatagggcta
      781 ggctgttata cagctacaat aattggggaa cttggaagta aaataattca aggatatgta
      841 agggtgtttg taatttattc actaacagca gccatgtatt tcttattatt ttacagtctg
      901 tatgcttttt tatctgcagg aaaacaaggg tttagacaat tctggagaaa tgctataaaa
      961 ccaatagcaa cggcactagc tacttcttca agttcagcat gtataccatc aaatttagaa
     1021 gctagtaaaa atataggagt tcctgatgat atatcagaaa cagttatacc tcttggaata
     1081 aatatacata aagatgggtc agttttagca gtaataataa aagtggcatt tttatcaggt
     1141 attttaggta gtggaatggc aaatccagca acgataggtc aattatttat aactgtattt
     1201 gttgttggag tatttatggc tcctgtagca ggtggctgac ttattggtga gatgctcgtg
     1261 gttagcatct tcggttttcc agtggaggca attccactgt taacagttat aactactata
     1321 actgatattc ctaatactat attaaataca actggaaata cagtatcatc aatgttagtt
     1381 tcaagattag tagaaggaaa agattggctt atagataaaa cagcaattac tacaaagaaa
     1441 ataagctaat tgtacactta attaataaag ttaataggta tcttaatttt aataaattag
     1501 atacctatta actttttaag taaaaatata aatttaagat tcaaatatga tatttataat
     1561 ttga
//
LOCUS       DAEPUT010000197         1455 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.203, whole genome shotgun sequence.
ACCESSION   DAEPUT010000197 DAEPUT010000000
VERSION     DAEPUT010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.203"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            21..209
                     /locus_tag="KRL22_003897"
     CDS             21..209
                     /locus_tag="KRL22_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274296.1"
                     /translation="MEYMSCPEAAKKWGISERRVQILCREKRIQGVSKLGYMWLIPKD
                     AEKPIDGRTKQGKELYHE"
     gene            202..894
                     /locus_tag="KRL22_003898"
     CDS             202..894
                     /locus_tag="KRL22_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1274297.1"
                     /translation="MNKVLIIDDDKELCALIKRSVLSEDIEADFCNTGKEGLQKLKER
                     EYQLVILDIMMPGMDGFETLEEIRKENSLPILMFTSKNDSASKVRGLRAGADDYLTKP
                     FDMDELIARIISLIRRYTRFNQQDGISQQLEFDGLKIDIENRSVTTENGTFELPPKEF
                     DLLLYCAKNQGKILTKQQIYEEVWREEYFYDDSNIMAIISRLRKKLEVNPGSPKYIQT
                     IKGIGYRFNKEV"
     gene            901..>1455
                     /locus_tag="KRL22_003899"
     CDS             901..>1455
                     /locus_tag="KRL22_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1274298.1"
                     /translation="MEAVIFLSIIIALFSILVSCFAIRRVKKQIAEITDALIDVKNGN
                     GNRRILSATNELVAPLAYEINEIVVSYESRLSTVRQTEETNRQLMTSLSHDVRTPLTT
                     LIGYLDAAHKGIVTGKDRDDYIETARRKAHDLKEYIDVLFDWFKLNSNEFAMDINIVE
                     AAELTRNILIDWIPIFEDKQIDYNI"
BASE COUNT          496 a          236 c          321 g          402 t
ORIGIN      
        1 cagaaaggac gggtgttgtt atggaatata tgtcttgccc cgaagcagca aagaagtggg
       61 gaatttctga aaggcgggta cagatacttt gcagggagaa acgcatacag ggtgtttcaa
      121 aacttgggta tatgtggttg ataccaaaag acgcggaaaa accgattgac ggtagaacca
      181 aacaaggaaa ggagctatac catgaataaa gttttgatta tagatgatga taaggaactt
      241 tgtgcgctga ttaaacgcag cgtactatca gaagatatag aagctgattt ttgtaatacg
      301 ggaaaagagg gattacaaaa attaaaagag agagaatatc aacttgtgat actggacatt
      361 atgatgcccg gtatggacgg atttgaaaca ttggaagaaa ttagaaaaga aaacagcctg
      421 ccgattttga tgtttacatc aaaaaatgac agtgcttcta aagtacgcgg tttaagggca
      481 ggagctgatg attatttgac aaaacctttt gacatggacg aactgatagc ccgtatcatt
      541 tcccttatac gccgttatac ccgtttcaat caacaggacg gaatatcaca gcaacttgaa
      601 tttgacgggt tgaaaattga tattgaaaat cgttctgtta ctacggaaaa tggaactttt
      661 gaattgcctc caaaagaatt tgacttactc ttatactgcg cgaaaaatca agggaaaatt
      721 ctgacaaagc aacagattta tgaagaagtg tggagagagg aatatttcta tgatgacagc
      781 aacattatgg cgattatcag ccgacttcgc aagaaattag aggtaaatcc cggaagtcca
      841 aaatatattc aaacgattaa aggtatcggt tatcgtttta acaaggaggt ttgattttct
      901 atggaagcag tcatttttct atccataata attgcacttt tctctattct tgtttcctgc
      961 tttgctattc gacgtgttaa aaaacagata gccgagataa cagacgcatt gattgatgta
     1021 aaaaacggaa atggaaacag gcgtatttta tctgcaacaa atgaactggt agcccctctt
     1081 gcctatgaaa taaatgagat tgttgtgtct tatgagagca ggctttctac tgtccggcag
     1141 acagaagaaa caaaccgaca gcttatgaca agtctttccc atgatgttcg gacaccgctt
     1201 acaacgctta ttgggtatct tgacgctgca cataaaggaa ttgttacagg aaaagacagg
     1261 gacgactata tcgaaacagc ccgccgcaaa gctcacgatt tgaaagaata tattgatgtt
     1321 ctttttgact ggttcaaatt aaattctaat gagtttgcta tggatataaa tattgttgaa
     1381 gctgcggagc tgacacgaaa tatcttgatt gactggatac ccatatttga agataagcag
     1441 atagattaca atatt
//
LOCUS       DAEPUT010000198         1337 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.204, whole genome shotgun sequence.
ACCESSION   DAEPUT010000198 DAEPUT010000000
VERSION     DAEPUT010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.204"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            27..101
                     /locus_tag="KRL22_003900"
     tRNA            27..101
                     /locus_tag="KRL22_003900"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="KRL22_003901"
     tRNA            116..200
                     /locus_tag="KRL22_003901"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="KRL22_003902"
     tRNA            210..293
                     /locus_tag="KRL22_003902"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            323..399
                     /locus_tag="KRL22_003903"
     tRNA            323..399
                     /locus_tag="KRL22_003903"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:357..359,aa:Arg,seq:tct)
     gene            407..482
                     /locus_tag="KRL22_003904"
     tRNA            407..482
                     /locus_tag="KRL22_003904"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Gln,seq:ttg)
     gene            571..659
                     /locus_tag="KRL22_003905"
     tRNA            571..659
                     /locus_tag="KRL22_003905"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:605..607,aa:Ser,seq:tga)
     gene            663..738
                     /locus_tag="KRL22_003906"
     tRNA            663..738
                     /locus_tag="KRL22_003906"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Phe,seq:gaa)
     gene            745..818
                     /locus_tag="KRL22_003907"
     tRNA            745..818
                     /locus_tag="KRL22_003907"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Met,seq:cat)
     gene            833..909
                     /locus_tag="KRL22_003908"
     tRNA            833..909
                     /locus_tag="KRL22_003908"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:867..869,aa:Ile,seq:cat)
     gene            933..1009
                     /locus_tag="KRL22_003909"
     tRNA            933..1009
                     /locus_tag="KRL22_003909"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:967..969,aa:Pro,seq:tgg)
     gene            1017..1093
                     /locus_tag="KRL22_003910"
     tRNA            1017..1093
                     /locus_tag="KRL22_003910"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:His,seq:gtg)
     gene            1102..1177
                     /locus_tag="KRL22_003911"
     tRNA            1102..1177
                     /locus_tag="KRL22_003911"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1135..1137,aa:Lys,seq:ttt)
     gene            1185..1258
                     /locus_tag="KRL22_003912"
     tRNA            1185..1258
                     /locus_tag="KRL22_003912"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1217..1219,aa:Cys,seq:gca)
     gene            1265..1336
                     /locus_tag="KRL22_003913"
     tRNA            1265..1336
                     /locus_tag="KRL22_003913"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Asn,seq:gtt)
BASE COUNT          321 a          309 c          355 g          352 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttgt
      301 ttgatataca tatataaatt gtgggtgcat agctcagctg gatagagcaa cgcccttcta
      361 aggcgtgtgt ccggggttcg aatccctgtg cgctcaccac atatattggg gattagccaa
      421 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      481 caaatgatgt attactaagc tatatttgaa ttatttttat tttaaatata gttaggttca
      541 attttagaat aagtttaagt atccgaatgt ggagaggtgt ccgagtggtt taaggagctg
      601 gtcttgaaaa ccagtgactt cgaaaggggc cgtgggttcg aatcccaccc tctccgccaa
      661 atgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc ggtggttcga
      721 ttccgcctct gggcaccaaa atatggcggt atagcttagt tggctagagc gttcggttca
      781 tacccgaaag gtcataggtt cgactcctat taccgctact aaaatttaat gtgggccatt
      841 agctcagttg gttagagcgc ccggctcata accggtaggt ctggggttcg agtccctgat
      901 ggcccaccac attaaattaa ttaatataaa ttcgaggtgt agcgcagttt ggtagcgcac
      961 atggtttggg accatggggc cgggggttcg agtcccttca cctcgaccaa tataaggtgg
     1021 gtatagctca gttggttaga gcgccagatt gtggctctgg aggtcgtgag ttcgactctc
     1081 attatccacc ccaattcata tggtctatta gctcagtcgg tagagcacct gacttttaat
     1141 cagggtgtcc cgcgttcgag tcgcggatag atcaccaaaa aggtggcgac atagccaagt
     1201 ggtaaggcag tggactgcaa ctccttgatc cccagttcga atctgggtgt cgcctccaaa
     1261 atattccaag gtagctcaac ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
     1321 agccccaccc ttggagc
//
LOCUS       DAEPUT010000199         1294 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.205, whole genome shotgun sequence.
ACCESSION   DAEPUT010000199 DAEPUT010000000
VERSION     DAEPUT010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.205"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            72..1230
                     /locus_tag="KRL22_003914"
                     /pseudo
     CDS             72..1230
                     /locus_tag="KRL22_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005608406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          431 a          263 c          273 g          327 t
ORIGIN      
        1 aagacacttc aagagacatt tcttaatgaa tctgatatac tgtaaacact acagaaagaa
       61 ggattattat tatgtctcga acaagaagaa atttctctgc caaattcaaa tcagaattag
      121 tgattgaact gctcaaagga gaaaaagact taaatacaat cgcaaccgaa aacaatattc
      181 agccgaatct tctccgcaac tggaagaagg agttcctcga taaagcatcc gtggttttta
      241 atgacacacg agaggataat ctgaaagaaa aactcgcttt agaacgcaag gaaaaagctg
      301 aatatgcgaa aaaagttggc cagctcacca tgcaggtgga ttggttgaaa aaaaaatctg
      361 aagaaacact tggacctgac tacgagagta aatttagtcc aaaacctttt gaagactaaa
      421 gaacttccag ttaaaacagg agctacactt cttgatatca atcgtaccag tgtttattac
      481 aagggcatgc ccatatctca ggaggagttg gattgcaaat cgatcataga tcgattacac
      541 acggataatc cggcctgggg agcacgacaa ctgtctgctc aactgaagaa gcgtgggcat
      601 caggttggtc gccggaaaac gcgccgttat atgaatgaaa tggggattga tccaatttat
      661 ccaaaaatga acctttctaa acgtatgcga caggctaaag tctgcccgta tctgctacgt
      721 aacgccgtta tcgaccgtcc aaatcaggca tggtcaatcg acattacata catccccatt
      781 aagcgtggat ttctgtatct gaccgctgtg attgactggt acagccgctg tatcgttggc
      841 tgggaagtcg atgatactct ggataccaga atggtcataa ctgcgttaaa aaaggcgttt
      901 atagtggcaa aacctgttat cctgaattca gatcagggct gtcagtttac aagcaatgag
      961 tacatgaatt tcctcaaaga gaaccagatc cgtcaaagca tggatggtaa aagccggtgg
     1021 gctgacaata tcatgattga acgatggttc cgaagcttca agtacgagga agcatatctg
     1081 acccaatata acaatatcag agaagcacgg aaggcaatcg gtaaatatgt gcacacttac
     1141 aactttgaac gttgtcattc tgcactcaat aatcaaacac cggcatcctg ctattatccg
     1201 attctgttac tggatgatca tgcagcctaa ggggggattt tctcccctac ccagttacat
     1261 atatcagttc attataaaaa gcttagattt ttgt
//
LOCUS       DAEPUT010000200         1257 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.206, whole genome shotgun sequence.
ACCESSION   DAEPUT010000200 DAEPUT010000000
VERSION     DAEPUT010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1257
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.206"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..>1257
                     /locus_tag="KRL22_003915"
     rRNA            <1..>1257
                     /locus_tag="KRL22_003915"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          326 a          276 c          385 g          270 t
ORIGIN      
        1 tgattagcta gttggtaagg taacggctta ccaaggcgac gatcagtagc cgacctgaga
       61 gggtgatcgg ccacattgga actgagacac ggtccaaact cctacgggag gcagcagtgg
      121 ggaatattgc acaatgggcg aaagcctgat gcagcaacgc cgcgtgagtg atgaaggcct
      181 tcgggtcgta aaactctgtc ctcaaggaag ataatgacgg tacttgagga ggaagccccg
      241 gctaactacg tgccagcagc cgcggtaata cgtagggggc tagcgttatc cggatttact
      301 gggcgtaaag ggtgcgtagg cggtctttca agtcaggagt gaaaggctac ggctcaaccg
      361 tagtaagctc ttgaaactgg gagacttgag tgcaggagag gagagtggaa ttcctagtgt
      421 agcggtgaaa tgcgtagata ttaggaggaa caccagttgc gaaggcggct ctctggactg
      481 taactgacgc tgaggcacga aagcgtgggg agcaaacagg attagatacc ctggtagtcc
      541 acgctgtaaa cgatgagtac taggtgtcgg gggttacccc cttcggtgcc gcagctaacg
      601 cattaagtac tccgcctggg aagtacgctc gcaagagtga aactcaaagg aattgacggg
      661 gacccgcaca agtagcggag catgtggttt aattcgaagc aacgcgaaga accttaccta
      721 agcttgacat cccaatgaca tctccttaat cggagagttc ccttcgggga cattggtgac
      781 aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga
      841 gcgcaaccct tgtctttagt tgccatcatt aagttgggca ctctagagag actgccaggg
      901 ataacctgga ggaaggtggg gatgacgtca aatcatcatg ccccttatgc ttagggctac
      961 acacgtgcta caatgggtag tacagagggt tgccaagccg taaggtggag ctaatccctt
     1021 aaagctactc tcagttcgga ttgtaggctg aaactcgcct acatgaagct ggagttacta
     1081 gtaatcgcag atcagaatgc tgcggtgaat gcgttcccgg gtcttgtaca caccgcccgt
     1141 cacaccacgg gagttggaga cgcccgaagc cgattatcta accttttgga agaagtcgtc
     1201 gaaggtggaa tcaataactg gggtgaagtc gtaacaaggt agccgtatcg gaaggtg
//
LOCUS       DAEPUT010000201         1208 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.207, whole genome shotgun sequence.
ACCESSION   DAEPUT010000201 DAEPUT010000000
VERSION     DAEPUT010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1208
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.207"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            107..1183
                     /locus_tag="KRL22_003916"
     CDS             107..1183
                     /locus_tag="KRL22_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH1274299.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
BASE COUNT          467 a          173 c          215 g          353 t
ORIGIN      
        1 ataaatttta tgttgacata gttaattcag cttgatatta tagttattaa aaataaggac
       61 agtaaaaacg ctatccatat tacaaactaa aaagggggga attataatga gtaagaaatt
      121 atttattcct ggtcctattg atgttaaaga agaagtcttg caaaagatgg ctacaccaat
      181 gataggacat agaggaaaag atgcatctat gctccaaaag agtataagtg aaaagatgca
      241 aaaactattc tatacaaaca acacgatact tttatccacg tcatccggaa ctggtttaat
      301 ggaaggctcc attcgttcct gtacatccaa aaaggcagca gtattttcct gtggatcctt
      361 tggtgataga tggtacaaaa tggcagtggc taataatgtc ccagcggata tatttaaagt
      421 tgaattagga gaggcaacaa cgccagaaat ggttgataag gtgctttcta ccggagaata
      481 cgatttaata actgtaactc acaatgaaac ttcaactgga ataagaaatc caatagaaga
      541 aattggagaa gttgttaaaa agtatgaaga tgtaatctac tgtgtagata ctgtaagttc
      601 agccggtgga ataaaagtcg aggttgataa gattggaata gatatttgta taacatcagt
      661 acaaaaagca ctgggattac caccaggaat gtctatttgc acattttctc aaaaagcaat
      721 cgatagagct aagcaagtac cttttagagg agtatatctt gatttgttag caatgtatga
      781 atacttaatc aagaaaaact accaataccc ttcaacacca tctctttctc acatgttcgc
      841 tttagatttc caattagata atatattaga tgaaggccta gataacagat tcaacagaca
      901 tgaagacatg gcaaacttag ttagaaactg ggctaaaaaa cacttccaaa tttttaccaa
      961 tgaaaatcac ttatccaata cacttactgt tatagaaaat actcaaggta ttagtgtatc
     1021 aaatttaaat tcaaaattac aagaacgagg attccaaata gcaaatggct atggagattt
     1081 aaaagaaaaa acttttagaa tttcacatat gggtgactat actgtcgaag atgtacaaga
     1141 attattagat aatattgatg atatattagg ttttaataaa taatattgta aaaatatgta
     1201 tgttttaa
//
LOCUS       DAEPUT010000202         1145 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.208, whole genome shotgun sequence.
ACCESSION   DAEPUT010000202 DAEPUT010000000
VERSION     DAEPUT010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1145
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.208"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..368)
                     /locus_tag="KRL22_003917"
     CDS             complement(<1..368)
                     /locus_tag="KRL22_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274300.1"
                     /translation="MQSILDAINEWIKEILIGAINGNLSTMFGDVNEKVGTIANEVGQ
                     TPQGWNANIFSMIQTLSENVIVPIAGLVITYVLCYELISMVTEKNNMHDIETFMFFKW
                     IFKAFVAVFIVTNTFNITMAV"
     gene            complement(385..600)
                     /locus_tag="KRL22_003918"
     CDS             complement(385..600)
                     /locus_tag="KRL22_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBH1274301.1"
                     /translation="MEFFNSAIGVLQTLVIALGAGLGIWGVINLLEGYGNDNPGAKSQ
                     GIKQLMAGGGVALIGTILVPLLSGLFG"
     gene            complement(800..967)
                     /locus_tag="KRL22_003919"
     CDS             complement(800..967)
                     /locus_tag="KRL22_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274302.1"
                     /translation="MNRRIRKKKDKKITEAINGLVSIAEWQEKQRQAAIRQFVKRCEA
                     LYEQQRKERRN"
     gene            complement(960..>1145)
                     /locus_tag="KRL22_003920"
     CDS             complement(960..>1145)
                     /locus_tag="KRL22_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007037036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBH1274303.1"
                     /translation="FSDKYDITKHPNYKYLSDYDKKNTFDMEKHLRRRPALVKPDEVF
                     DYYEISESDLQEDTDHE"
BASE COUNT          262 a          282 c          254 g          347 t
ORIGIN      
        1 actgccattg tgatgttgaa cgtgttggtt acgataaaca ccgcgacaaa ggctttgaat
       61 atccacttaa agaacatgaa tgtttctatg tcgtgcatat tgttcttttc cgttaccatg
      121 ctgattagct cgtagcatag gacataggta atgacaagcc ccgcaatcgg gacgattaca
      181 ttttcagaaa gggtctgtat catgctgaaa atgtttgcgt tccaaccctg cggggtctgt
      241 cctacctcgt ttgcgatagt cccgactttt tcgtttacgt ccccgaacat agttgacaga
      301 ttaccgttta tcgctccgat aaggatttcc tttatccatt cgttaatcgc gtcaagtatg
      361 ctctgcatag gcagctaccc gcgcttaacc gaacaagccg gaaagcagag gtacaaggat
      421 agtgccgata agggcaacgc cgccgcccgc catgagctgt ttaatgccct gtgattttgc
      481 acccggattg tcgtttccat atccctctaa gagattgata acgccccaaa tgccaagtcc
      541 tgctccaaga gcgataacca aagtctgtaa tacgccgatt gcactgttga aaaattccat
      601 aaaactcctt tctgccgcaa atgcggcttg ccccgtaaaa gggcataaaa aacggcggtc
      661 agttttcaaa ctgccgcggt cataagtccc cgcgctgcgt aaagttctgc cgcgcggcgg
      721 tattcagttg tcagtgtggg cgataggaat ttttgtaggg gcgcgtatca tgcaagttgt
      781 ctttttcttt gttactgcgt caattcctcc tttcttttcg ctgctgctca tacagggctt
      841 cacaccgttt cacaaactgc cggatagcag cctgccgctg tttttcctgc cactcggcaa
      901 tcgaaaccag tccgtttatg gcttctgtga ttttcttgtc ctttttcttt ctgatacgtc
      961 tattcatggt cggtgtcctc ctgcaaatcg ctttcgctga tttcgtagta gtcaaatact
     1021 tcgtccggct tcacaagggc gggtctgcgc cttaaatgct tctccatatc aaaagtattt
     1081 ttcttgtcat agtcggaaag atatttatag ttggggtgct ttgtaatgtc gtacttatca
     1141 gagaa
//
LOCUS       DAEPUT010000203         1145 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.209, whole genome shotgun sequence.
ACCESSION   DAEPUT010000203 DAEPUT010000000
VERSION     DAEPUT010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1145
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.209"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            197..337
                     /locus_tag="KRL22_003921"
     CDS             197..337
                     /locus_tag="KRL22_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274304.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(334..705)
                     /locus_tag="KRL22_003922"
     CDS             complement(334..705)
                     /locus_tag="KRL22_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274305.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
BASE COUNT          443 a          115 c          138 g          449 t
ORIGIN      
        1 tgttattatt acgagttttt tattgcaact gtagaataaa agtattatta tataattaag
       61 ataattatct agggaaattt tggataatca aaatatattt tataaaatca aaatacaatt
      121 acataaactt tattaaaaat ttgttgggaa tttctgacta acattaagaa cgtaagtttg
      181 ttgggggatg gtatatgtgg aaaagtcaaa cactactgtt acaaaaaaag aaaaaattga
      241 agatatagga atgaaattag aacatttatt gagtgaagat attacttttt atgaattatt
      301 acttgagatt ttgtataaag aaaaagaaga gaattaattc tcttctttaa ggaatctttt
      361 taaataggca ttatcaatca ttttttctat agcttctcta tcttcttttt caagagaata
      421 tattttttct aagagctttt ttgttttttc acttactgat aagttctcta tgattaattt
      481 atcttctttg cttatttttg tattatcatt tacgcctaat aaataatctg ttgatgtttc
      541 taatgctttt gctaatctaa ctattatttc acttttaggt tctcttaaat tattttcata
      601 acgtgacaag ctagcctcag ttataccgac tttagtagca agttcttttt gatttatatc
      661 taattctttt cgtagatttg ctattctatc tcctaaactt tccatatgta catcactcct
      721 taccgaaatt ataagttatt ttgataaaaa gtaaaataaa attaccaaaa atataaaaaa
      781 aaaaggttaa aataataaaa tatattgaaa attaccattt gtatatgtat aatatgaatt
      841 atacaaatgg taatttgatg agaggtggta tgttgaaata agaaactgaa ttaattaata
      901 aatacataga aagttttgaa aacctttaat tgagatataa acaatatgta caaaattttt
      961 tgcaagtaaa attaccaaat gtataaaata aatcagtagc atagataatt ttatgcttta
     1021 atacattaga ttatttaatt tagttataat ggtcaaaaat gcaatctaca aataaaacaa
     1081 agtattatca aaaaagtatt ctttaagaaa attttttatt agagatgtaa ttgatataaa
     1141 taatc
//
LOCUS       DAEPUT010000204         1144 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.210, whole genome shotgun sequence.
ACCESSION   DAEPUT010000204 DAEPUT010000000
VERSION     DAEPUT010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1144
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.210"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..368)
                     /locus_tag="KRL22_003923"
     CDS             complement(<1..368)
                     /locus_tag="KRL22_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002595174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274306.1"
                     /translation="MQSILDAINEWIKEILIGAINGNLSTMFGDVNEKVGTIANEVGQ
                     TPQGWNANIFNMIQTLSENVIVPIAGLVITYVLCYELISMVTEKNNMHDIETFMFFKW
                     IFKAFVAVFIVTNTFNITMAV"
     gene            complement(385..600)
                     /locus_tag="KRL22_003924"
     CDS             complement(385..600)
                     /locus_tag="KRL22_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBH1274307.1"
                     /translation="MEFFNSAIGVLQTLVIALGAGLGIWGVINLLEGYGNDNPGAKSQ
                     GIKQLMAGGGVALIGTILVPLLSGLFG"
     gene            complement(799..966)
                     /locus_tag="KRL22_003925"
     CDS             complement(799..966)
                     /locus_tag="KRL22_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274308.1"
                     /translation="MNRRIKKKKDKKITEAINGLVSIAERREQQRQAAIRQFVKRCEA
                     LYEQQRKERRN"
     gene            complement(959..>1144)
                     /locus_tag="KRL22_003926"
     CDS             complement(959..>1144)
                     /locus_tag="KRL22_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007037036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBH1274309.1"
                     /translation="FSDKYDITKHPNYKYLSDYDKKNTFDMEKHLRRRPALVKPDEVF
                     DYYEISESDLQEDTDHE"
BASE COUNT          267 a          278 c          251 g          348 t
ORIGIN      
        1 accgccattg tgatgttgaa tgtgttggtt acgataaaca ccgcaacaaa ggctttgaat
       61 atccacttaa agaacatgaa tgtttctatg tcgtgcatat tgttcttttc cgttaccatg
      121 ctgataagct cgtagcatag gacataggta atgacaagcc ccgcaatcgg gacgattaca
      181 ttttcagaaa gggtctgtat catattgaaa atgtttgcgt tccaaccctg cggggtctgt
      241 cctacctcgt ttgcgatagt tccgaccttt tcgtttacgt ccccgaacat agttgacaga
      301 ttaccgttta tcgctccgat aaggatttcc tttatccatt cgttaatcgc gtcaagtatg
      361 ctctgcatag gcagttaccc gcgcttaacc gaacaagccg gaaagcaaag gtacaaggat
      421 agtgccgata agggcaacgc cgccgcccgc catgagctgt ttaatgccct gtgattttgc
      481 acccggattg tcgtttccat atccctctaa gagattgata acgccccaaa tgccaagtcc
      541 tgctccaaga gcgataacca aagtctgtaa tacgccgatt gcgctgttga aaaattccat
      601 aaaactcctt tctgccgcaa atgcggcttg ccccgtaaaa gggcataaaa aacggcggtc
      661 agttttcaaa ctgccgcggt cataagtccc cgcgctgcct aaatgtctgc cgcgcggcgg
      721 tattcagttg tcagtgtggc gataggaatt tttgtagggg cgcgtatcat gcaagttgtc
      781 tttttctttg ttactgcgtc aattcctcct ttcttttcgc tgctgctcat acagggcttc
      841 acaccgtttc acaaactgcc ggatagcagc ttgccgctgc tgttcccgcc gttcagcaat
      901 agaaacaagc ccgtttatgg cttctgtgat tttcttgtcc tttttctttt tgatacgtct
      961 attcatggtc ggtgtcctcc tgcaaatcgc tttcgctgat ttcgtagtag tcaaatactt
     1021 cgtccggctt cacaagggcg ggtctgcgcc ttaaatgctt ttccatatca aaagtatttt
     1081 tcttgtcata gtcggaaaga tatttatagt tggggtgctt tgtaatgtcg tacttatcag
     1141 agaa
//
LOCUS       DAEPUT010000205         1140 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.211, whole genome shotgun sequence.
ACCESSION   DAEPUT010000205 DAEPUT010000000
VERSION     DAEPUT010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1140
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.211"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(<1..307)
                     /locus_tag="KRL22_003927"
     CDS             complement(<1..307)
                     /locus_tag="KRL22_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274310.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     "
     gene            complement(329..667)
                     /locus_tag="KRL22_003928"
     CDS             complement(329..667)
                     /locus_tag="KRL22_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274311.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT          380 a          141 c          117 g          502 t
ORIGIN      
        1 tcttttttat gatgtctata atctgtgata tcagatttag ttctcttgaa tttaagtctt
       61 ttaactcttc atttatatca ttttctaaat atgtttttcc agtggaagta atatctttta
      121 taagaacatc tgcagaaata tttaatatat ttacaaattt tatgaatgtt ttaagacttg
      181 gattcttttt accactttcg atttgagtta tataccaagg cgatactcca accatatttg
      241 caaattcttt tgaagttaaa tttgcttttt tccgttcttc tttaagtctt ttacctatat
      301 aattcattat tgttactatt tccctcactt atatttcttt gtatttaatg atgcacttta
      361 ttaactctag cattgcaatt tgttcttttt cagttaattt attaatcatt tcataacatt
      421 ctaaaggtac agagttatca acgccttctg ttgtaataat atttgcaaat aacaattcaa
      481 gtggtatgtc taaagcagta gcaattttca ttataatatt gatagatgta tttgtctcag
      541 ctctttcaat ctgaccaata tatgttggat gtaaacctgc cttttctgct agaaactctt
      601 gactatatcc caattttgtt ctatagactt ttattctatc tcctattatt tttcctatat
      661 ttgccaatta ttatccctcc actttagatt atattcatag tttaagttgt tttatataga
      721 ctatttatac ttttttagtc taaatataga ctatatatgt ttttatactg aaataagtgc
      781 tatttatttt tgtatagtct gtatctacaa taaacaaata tggataaatc atatttttaa
      841 ttagagaaat attttcataa tttcatagcc atactacaat aataaaacga attaataata
      901 tgttaattat agcatttttt attgtaatta catattagat atgtagaata tattttgaaa
      961 attaaaaaaa ttttctattt tatatattga acaatttatg taaatagaaa atttttcaat
     1021 aagacttttg agtttaatca ttatattggt aaggtaaaca tttttaaatc taattatata
     1081 taggtgaaat aaaaaattaa ttataagtaa ggcatttaga ataaaatttt aaaaaaatta
//
LOCUS       DAEPUT010000206         1004 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.212, whole genome shotgun sequence.
ACCESSION   DAEPUT010000206 DAEPUT010000000
VERSION     DAEPUT010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1004
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.212"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..906
                     /locus_tag="KRL22_003929"
     CDS             <1..906
                     /locus_tag="KRL22_003929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBH1274312.1"
                     /translation="VSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFK
                     TQKDKLVSQAKKIASPSKGKTELEEIRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVM
                     AIFTNRLGASKKGRLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPM
                     AKVYSANCYTPEGRKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKC
                     AITLEEFQQANEIHCHHIVPTRAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALL
                     KLNKVQLIRLNKYRVLAGNQELNLI"
BASE COUNT          404 a          156 c          188 g          256 t
ORIGIN      
        1 gtatcacaag aaaaaacaag aattgtaaat gttagaaaaa gatactccga ctttcttggt
       61 ttcaagatta aaatgatacc gagaagaaag aagttagttg ttaaatcaca tataagtgat
      121 aaacaattca agacccaaaa agacaagctg gtatcacagg caaagaaaat tgcttctccc
      181 tcaaagggaa aaacagaatt agaggaaata agactttata attcaatggt attaggtatg
      241 caaaattatt atcagattgc aacaaatgta aatctggatt gtatgaaact taatagagct
      301 gtaatggcta tcttcactaa cagattaggt gcaagcaaaa agggcagatt gagaaaaaca
      361 ggcagacaac ttacaacaaa agaagcaaca agatatggta aatctaaaat gcttcgatat
      421 gttgctggcg agggcgaacc tatattccct gttggatata tccaacacag aaaaccaatg
      481 gcaaaagtgt attcagcaaa ctgctatact ccagagggaa gaaaatttat ccataccaat
      541 ctaagtgttg ataaattact gatgtatcag ttgatgaaat tatctttgga aaatcgcaca
      601 atagaatacg cagacaatcg aatttcgcta ttttctgccc aacatggaaa atgtgctata
      661 actctggaag aatttcaaca agctaatgaa atacactgtc atcatattgt accaactagg
      721 gctggtggta atgacgatta taaaaatctt attttggtaa aagaggcggt acatcgtcta
      781 atacacgcaa aaacagaaga aacaatacaa aaatatatag ctctattgaa actaaataaa
      841 gtccagctca taagactaaa taaatataga gtattagctg gcaatcaaga attaaacttg
      901 atataggtct actacataaa tacttttcaa tataaacacg atggaacgcg gagtgcggtg
      961 aaagtcgcac gctccgtgtg aatgggggga aaagtttgag atat
//
LOCUS       DAEPUT010000207          995 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.213, whole genome shotgun sequence.
ACCESSION   DAEPUT010000207 DAEPUT010000000
VERSION     DAEPUT010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..995
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.213"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..341
                     /locus_tag="KRL22_003930"
     CDS             <1..341
                     /locus_tag="KRL22_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016291774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1274313.1"
                     /translation="VKLDTDGYMRILNNLIQNVISHSHADKIEIILSKQEKNMQIRLA
                     DNGIGIEKEDLKHIFERLYKCDKGRSEKGSGLGLSIAHQLVEKMNGTITANSIQGKGT
                     EFTLLFPLAK"
     gene            478..>995
                     /locus_tag="KRL22_003931"
     CDS             478..>995
                     /locus_tag="KRL22_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016281052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1274314.1"
                     /translation="MDKNYIIETKNLTKQYGSQKSVADLNIHVQKGRIYGLLGRNGAG
                     KTTTMKMLLGLTKPTSGEVKIWGKSLQGNEKKLLPRIGSLIESPGFYPNLTATENLQI
                     FATLRGVPNRHAIKDALDLVGLPYKDKKLFSQYSLGMKQRLAIALAVMHDPELLILDE
                     PINGLDPIGIAEV"
BASE COUNT          335 a          169 c          228 g          263 t
ORIGIN      
        1 gggtaaaact tgatacggac ggctatatgc ggatattgaa caatcttatt caaaatgtaa
       61 tttctcacag tcatgcggat aaaatagaaa taatcctgtc aaagcaggaa aaaaatatgc
      121 aaatccgatt agcagataat ggaataggga ttgaaaaaga agatttgaag catatttttg
      181 aacggctcta taaatgcgat aagggacggt ctgaaaaagg cagcggtctt gggctttcta
      241 tcgcacacca acttgtagaa aagatgaacg gcacaataac agcaaatagc atacagggaa
      301 aaggaacaga atttactttg ctttttccct tagcaaagta aggttctccc gtccttttga
      361 cgggagcctt aattatttgg ggagaaatat ttcaaattgc aaggttaatg caaggttgcg
      421 gcaaggttaa tgcaaggttg gtgtgataga atactttaca gaacaggagg tttgaatatg
      481 gacaaaaatt atatcattga aacaaaaaat cttacaaaac agtacggctc acaaaagagt
      541 gttgctgact taaatattca tgtgcagaaa gggagaattt acggactgct tggaagaaac
      601 ggagccggaa aaacgaccac tatgaaaatg ctacttggat tgacaaagcc aacttccggc
      661 gaagttaaaa tatggggaaa gtctttgcag gggaatgaaa agaaattgtt gccccgtatc
      721 ggtagtctga ttgagtcgcc cggtttttac cctaatttga ctgctacgga aaacttacaa
      781 atttttgcta ccttacgggg agtaccaaac cgccacgcaa tcaaagacgc tttagatttg
      841 gtgggattgc cttataaaga caaaaaactg ttttcccagt attctcttgg tatgaaacaa
      901 cggcttgcga ttgcacttgc tgttatgcac gacccggagc ttttgatttt agatgaacct
      961 atcaatgggc ttgacccgat tggaattgca gaggt
//
LOCUS       DAEPUT010000208          995 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.214, whole genome shotgun sequence.
ACCESSION   DAEPUT010000208 DAEPUT010000000
VERSION     DAEPUT010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..995
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.214"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..341
                     /locus_tag="KRL22_003932"
     CDS             <1..341
                     /locus_tag="KRL22_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1274315.1"
                     /translation="VKLDTDGYMRILNNLIQNVISHSHADKIEIILSKQEKNMQIRLA
                     DNGIGIEKEDLKHIFERLYKCDKGRSEKGSGLGLSIAHQLVEKMNGTITANSIQGTGT
                     EFTLLFPLAN"
     gene            478..>995
                     /locus_tag="KRL22_003933"
     CDS             478..>995
                     /locus_tag="KRL22_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016281052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1274316.1"
                     /translation="MDKNYIIETKNLTKQYGSQKSVADLNIHVQKGRIYGLLGRNGAG
                     KTTTMKMLLGLTKPTSGEVKIWGKSLQGNEKKLLPRIGSLIESPGFYPNLTATENLQI
                     FATLRGIPNRHSIKNTLDLVGLPYKDKKLFSQYSLGMKQRLAIALAVMHDPELLILDE
                     PINGLDPIGIAEV"
BASE COUNT          336 a          173 c          220 g          266 t
ORIGIN      
        1 gggtaaaact tgatacggac ggctatatgc ggatattgaa caatcttatt cagaatgtaa
       61 tttctcacag tcatgcggat aagatagaaa taatcctgtc aaagcaggaa aaaaatatgc
      121 aaatccgatt agcagataat ggaataggga ttgaaaaaga agatttgaag catatttttg
      181 aacggctcta taaatgcgat aagggacggt ctgaaaaagg cagcggtctt gggctttcta
      241 tcgcacacca acttgtagaa aaaatgaacg gcacaataac agcaaatagc atacagggaa
      301 caggaacgga atttactttg ctttttccct tagcaaatta aggttctccc gtccttttga
      361 cgggagcctt aattattttt gggacaatat ttcaaattgc aaggttaatg caaggttgcg
      421 gcaaggttaa tgcaaggttg gtatgataga atactttaca gaacaggagg tttgaatatg
      481 gacaaaaatt atatcattga aacaaaaaat cttacaaagc agtacggctc acaaaagagt
      541 gtcgccgact taaatattca tgtgcagaaa gggagaattt acggactgct tggaagaaac
      601 ggagccggaa aaacgaccac tatgaaaatg ctacttggat tgacaaagcc aacttccggc
      661 gaagttaaaa tatggggaaa gtctttgcag gggaatgaaa agaaattgtt gccccgtatc
      721 ggtagtctga ttgagtcgcc cggtttttac cctaatttga ctgctacgga aaacttacaa
      781 atttttgcta ccttacgggg catacccaac cgtcattcaa ttaaaaacac attggatttg
      841 gtaggattgc cttataaaga caaaaaactg ttttcccagt attctcttgg tatgaaacaa
      901 cggcttgcga ttgcacttgc agttatgcac gaccctgaac ttctgatttt agatgaacct
      961 atcaatgggc ttgacccgat tggaattgca gaagt
//
LOCUS       DAEPUT010000209          975 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.215, whole genome shotgun sequence.
ACCESSION   DAEPUT010000209 DAEPUT010000000
VERSION     DAEPUT010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..975
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.215"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            281..>975
                     /locus_tag="KRL22_003934"
     CDS             281..>975
                     /locus_tag="KRL22_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBH1274317.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGTPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMPDGTITYP"
BASE COUNT          382 a          158 c          196 g          239 t
ORIGIN      
        1 agcaggctta tagctagtga cctaaggata tatatgtata gataagatta tcggaacgag
       61 gaaaggtatt gggttctcat caagagaata agctgacgaa gaacaataag cagttgaacc
      121 aatgctgaaa agcagagggc gaacctaaga aattcttgta atgagaatgg aggaataccc
      181 tcaagtcgtg tatatattag aaaagtatta tgttgtttta ataaggatta cgagtaagat
      241 aaaaaagctc actcaatttc aagcaaagga gtgaagcctt atgcctaaaa ataaaaatga
      301 aacattgtgt gtagaagatt taagacacgc tgaatattac gaaatgcaaa acacctttga
      361 tgatttatat gccaaaagta agaatggaga tattttcact catcttatgg atattatcct
      421 atcgagagaa aatatattac tggcatatcg aaatatcaaa gcaaatgcag gcagtaagac
      481 agcaggaaca gacggtacaa taattaaaga tattggcaaa ttgccagcag aaacagttgt
      541 caaaaaggta agatatattg tcgcaggcac tccgcacggg tatcgaccta agccagtaag
      601 gcgaaaagaa ataccaaaac caaatgggaa aaccagacct ctaggcattc cttgtatgtg
      661 ggacaggctt atacaacaat gtatcaaaca agtattagaa ccaatctgcg aagctaaatt
      721 tagtgaaaac agctacggtt tcagacctaa taggtcggtt gaaaatgcaa taaaagcaac
      781 ctataaccgc ctacaaatca gccagctaca ttatgtgatt gaatttgata ttaagggttt
      841 ctttgacaac gtgaaccatt ccaaactgat aaaacagata tgggctatgg gaatacggga
      901 caagcacttg atattcattt taaaaaggat attaaaagct ccaattaaaa tgcctgacgg
      961 cacaataaca tatcc
//
LOCUS       DAEPUT010000210          924 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.216, whole genome shotgun sequence.
ACCESSION   DAEPUT010000210 DAEPUT010000000
VERSION     DAEPUT010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..924
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.216"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(175..888)
                     /locus_tag="KRL22_003935"
     CDS             complement(175..888)
                     /locus_tag="KRL22_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1274318.1"
                     /translation="MINIIICEGKKSERVILNDYINTFFYNYNFEYNIKEFENGGDLL
                     KKYPNNVDIIFMDIDLNDENGFNVSKEIKKFDESVRIIFVSSSNKYIKKGYEIGVYRY
                     LEKPLKYSLFKEAISSYLKECYKNEAILSIKCKCKIYFIKVDDILYLEVLKNDLTIHT
                     EKGIYTFKSSMKEIESNLEEHNFFRCHKSYLINLMKVNMLDIENNIVFINQNSIIVSR
                     YKIKLLREKLNSCLVDVII"
BASE COUNT          333 a          118 c           64 g          409 t
ORIGIN      
        1 attaaatctt taaaataaaa ttgttaatag aattgtaaaa taaaatctta atatattcaa
       61 tctgttattg atgaaaggta tatttttaac tataattagt ttttattata aattttttca
      121 tattttacaa tagatatatt ctattagaat agaatataaa ggcaaaaatt tacctcaaat
      181 tattacatct accaaacaac tatttaactt ttctctcaat aattttatct tataacgact
      241 tacaattatt gaattttgat ttataaatac aatattattt tctatatcta gcatatttac
      301 cttcattaaa tttataaggt agcttttatg acatctaaaa aaattatgtt cttctagatt
      361 tgattctatt tctttcatac tactcttaaa agtatatatt cctttttcag tatgtatagt
      421 taaatcattt tttaaaactt ctaaatataa aatatcatct acctttatga aatatatctt
      481 gcatttacat tttatagata aaatagcttc atttttgtag cattctttta aatatgatga
      541 tattgcttct ttaaatagag agtattttaa gggcttctct aaatatctat aaactcctat
      601 ctcataacct ttctttatgt atttatttga tgaggataca aatataattc ttacactttc
      661 atcaaatttt ttgatttctt ttgaaacatt aaatccattt tcatcattta agtctatatc
      721 cataaatatg atatcaacat tattaggata cttttttaat aaatcgcctc cattttcaaa
      781 ctctttgata ttgtattcaa aattgtaatt ataaaaaaag gtatttatat aatcatttag
      841 aattaccctc tctgattttt taccttcgca aataataata ttaatcatat tacacccctt
      901 atataatttt ttattttaaa tttt
//
LOCUS       DAEPUT010000211          831 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.217, whole genome shotgun sequence.
ACCESSION   DAEPUT010000211 DAEPUT010000000
VERSION     DAEPUT010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..831
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.217"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            96..662
                     /locus_tag="KRL22_003936"
     CDS             96..662
                     /locus_tag="KRL22_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HBH1274319.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
BASE COUNT          323 a           68 c          149 g          291 t
ORIGIN      
        1 taatttaata aatataaatt aaattatatg tgtatatatt gtactttaat agtgatataa
       61 taataaaaaa atttttaaag agggtgatat tacatatgag aaaacttgaa gagatattag
      121 aatataataa atcatttgta gagaacaaag aatatgaaca atatgtgaca tcaaaacatc
      181 caaataaaaa aatagtagtc ttatcttgta tggatacaag attaactgag cttttgccta
      241 aggctatgaa tttgaaaaat ggagatgtga aactaataaa aaatgcagga gctactataa
      301 tgcatccttt tggaagtatt atgagaagtg ttttagttgc aatttacgaa tttgatgtag
      361 atgaggttat ggttgtaggg catcatggat gtggtatgtg taatgttgat acggataagt
      421 tacttggtaa aattttagat agaggaatat ctaatgatgt aatacttaca cttcgtagtg
      481 ctggaattga tacaaaacaa tggttacatg gattcgattc tgcagaagaa tctgtaaaag
      541 atagtattga tttaataaaa gggcatcctt taattccaga tggtattatt gtacatggtc
      601 taattatatc acctgaaact gggaagttag atgttgttgt aaatggatat gaagataagt
      661 agagtatcat aatgttatat aatcaagata ctgttgaata tgatgttgtt tcaaaattta
      721 ttttgggaca acttttttat ttgaaaatat atgaaaaggt ttattttaag ctttacaata
      781 aaaaatataa gtagctgact aattaaaaat cttactatta tttattaaaa t
//
LOCUS       DAEPUT010000212          795 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.218, whole genome shotgun sequence.
ACCESSION   DAEPUT010000212 DAEPUT010000000
VERSION     DAEPUT010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.218"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            436..>795
                     /locus_tag="KRL22_003937"
     CDS             436..>795
                     /locus_tag="KRL22_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1274320.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKIRNITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRR"
BASE COUNT          338 a           51 c          115 g          291 t
ORIGIN      
        1 ggttaaaata attttatata tagtgcctaa tgtataacct aatgctcgta gacaataatg
       61 tggatattat caaatttatt tttataatag aaattttaat ttatatctat attaaattgt
      121 taaagatata attatgagaa taaaaaatat agctttgaat tatataattg tatatgctta
      181 tctttataca gtaaataaaa aatcaaatga aataccaaat aaagtgtata tcttaaaata
      241 acttactaga gatacaagga tgctatgtga attttgaagt gtgcagttta gataataaat
      301 atatataaat aataaagaaa atggatttat agtatttaaa atttcttata agggtaaaaa
      361 atgctattag aaaatgtact aaaaatattt ttccaattct ttatagaaaa ataatgatat
      421 ttaggagaga ttgtaatgca aattgatgta ttgataattg atggagataa gaatagttct
      481 caagagctga aaaatttttt agaaggaaag gggataaatg tctatttagc atataattgt
      541 aaagatgcta ttataaaaat atttagcaag aaatttgact taatattttt agagataatt
      601 ttagttgatg gtgatggttg ggatttttgt aaaaaaatta gaaatataac tacttgccca
      661 attattcata taacttatat aaatgaaaat caaagtattt taaatgcttt aaattctgga
      721 ggagatgatt atttaataaa gcctttaaat ttagaaatat tatatgcgaa agttaaagct
      781 attttaagaa gaaga
//
LOCUS       DAEPUT010000213          743 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.219, whole genome shotgun sequence.
ACCESSION   DAEPUT010000213 DAEPUT010000000
VERSION     DAEPUT010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..743
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.219"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..>743
                     /locus_tag="KRL22_003938"
     rRNA            <1..>743
                     /locus_tag="KRL22_003938"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          205 a          153 c          226 g          159 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaaggt
      661 ttccagggga aggttcgtcc gccctgggtt agtcgggacc taagctgagg ccgaaaggcg
      721 taggtgatgg acaacaggtt gat
//
LOCUS       DAEPUT010000214          685 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.220, whole genome shotgun sequence.
ACCESSION   DAEPUT010000214 DAEPUT010000000
VERSION     DAEPUT010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..685
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.220"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            95..>685
                     /locus_tag="KRL22_003939"
     CDS             95..>685
                     /locus_tag="KRL22_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1274321.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT          280 a           71 c          148 g          186 t
ORIGIN      
        1 aatcaataga ttaagtgaaa tgctaataaa ttaaaaaagt gaaatatcaa aataaaacgt
       61 caacaaatta aaaattatat gggggaatat caaaatgtta aatgaaacaa gaaaaaaaca
      121 attaactgaa gtatgccaag acttaataag aaatgctagt tattcaggtc aagaagaaaa
      181 cgtagtaaaa gctatagaag aaaattttgc tttactaggt tttgatagtt ggtcaagaga
      241 tagatatgga aatatagtag gatgtataaa aggaaataaa ccaggtaaaa aaatattatt
      301 tgacggacat atagatacag ttccagttcc agatgcaagt aaatggagtg ttcctccttt
      361 tgaagcgaga atagtagatg ggaaaatata tggtagagga acttctgata tgaaggggca
      421 agtaagtgct atgatggctg ctgtttcata ctttgcagaa gatactaaca aagactttga
      481 aggtgaattg tatgtagcag gtgttgttca tgaagaaata tttgaaggtg tttcagctag
      541 agagataagt aaggctgttc aacctgatta tgttgtaata ggtgaatctt cagaattaaa
      601 cctaaagata ggtcaaagag gtagaggaga aatagtagta gaaacttttg gtaaaccagc
      661 tcactctgct aatccagaaa aaggt
//
LOCUS       DAEPUT010000215          662 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.221, whole genome shotgun sequence.
ACCESSION   DAEPUT010000215 DAEPUT010000000
VERSION     DAEPUT010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.221"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            106..576
                     /locus_tag="KRL22_003940"
     CDS             106..576
                     /locus_tag="KRL22_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH1274322.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIEFVKQCENSKE"
BASE COUNT          288 a           55 c          121 g          198 t
ORIGIN      
        1 aaaaagtaaa aataaaggat taataaaagg tactgaagag atagagaaaa aaatgttaat
       61 agaagatact gaaaaaatag aaataaaaaa ttaggaggaa aatttatgaa atatcaggtt
      121 tcattattag cagtgaagga tattgaagta tcaaaaaaat tttacaaaga attatttgag
      181 caagaaattg aattggactt aggtaaaaat gtaacattta aaggaggatt tgctatacaa
      241 gaagacttcg catggcttac agggattaat ccagatacaa ttatacaaaa atcaaataat
      301 atggaacttt attttgaggt tgatgatttt gacgaattta ttgaaaaact caattattat
      361 aaagatgtag agtttgtcca taagccacta aaacatgaat ggcaacaaag agtagtgcgt
      421 atttatgacc cagataagca tattattgag ataggagagt ctatggaagt tatagctaga
      481 agatatttat ctgagggata ttctgtagaa gaaacttcta aaataattca acatccaatt
      541 gaatttgtaa agcagtgtga aaatagtaag gaatgattgt ttaaattata attatttagt
      601 agaaattaat tgtagtagaa ctaattcaag ataatatata ggactagtat ttgacaaatg
      661 tc
//
LOCUS       DAEPUT010000216          648 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.222, whole genome shotgun sequence.
ACCESSION   DAEPUT010000216 DAEPUT010000000
VERSION     DAEPUT010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..648
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.222"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..>648
                     /locus_tag="KRL22_003941"
     rRNA            <1..>648
                     /locus_tag="KRL22_003941"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          167 a          143 c          196 g          142 t
ORIGIN      
        1 actgtcaggt gggcagtttg actggggcgg tcgcctccca aaaggtaacg gaggcgctca
       61 aaggttctct cagtacggtc ggaaatcgta cgtagagtgt aaaggcaaaa gagagcttga
      121 ttgcaagaca tacaggtcga gcaaggatga aaatcggact tagtgatccg gtggttctgc
      181 gtggaagggc catcgctcaa cggataaaag ctaccctggg gataacaggc ttatctcccc
      241 caagagtcca catcgacggg gaggtttggc acctcgatgt cggctcatca catcctgggg
      301 ctgtagtagg tcccaagggt tgggctgttc gcccattaaa gtggtacgcg agctgggttc
      361 agaacgtcgt gagacagttc ggtccctatc cgtcgcaggc gtaggaaatt tgagaagacc
      421 tgtccttagt acgagaggac cgggatggac gtacctctgg tgtaccagtt gtcctgccaa
      481 gggcatggct gggtagctat gtacggaatg gataagcgct gaaagcatct aagcgcgaag
      541 ccaacttcaa gataagattt cccaccgcaa gggtaagacc ccagaaagac tatctggttg
      601 ataggtcgaa ggtgtaagtg cagcaatgta tttagcttat cgatacta
//
LOCUS       DAEPUT010000217          639 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.223, whole genome shotgun sequence.
ACCESSION   DAEPUT010000217 DAEPUT010000000
VERSION     DAEPUT010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..639
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.223"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..>639
                     /locus_tag="KRL22_003942"
     rRNA            <1..>639
                     /locus_tag="KRL22_003942"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          179 a          138 c          186 g          136 t
ORIGIN      
        1 ggatgtgatg gggagcgaaa tttagtagcg aagtagctga tttcacactg tcaagaaaag
       61 tctctatcga ggttaaaggt acccgtaccg caaaccgaca caggtgggtg aggagagtat
      121 cctaaggcca gcgagagaac tgttgttaag gaactcggca aaatgacccc gtaacttagg
      181 gataaggggt gccaccatca ggtggccgca gagaataggc ccaagcgact gtttaccaaa
      241 aacataggtt tctgctaagt cgcaagacga tgtataggag ctgacgcctg cccggtgctg
      301 gaaggttaag gggatctgtt agagcaatcg aagcagtgaa cttaagcccc agtaaacggc
      361 ggccgtaact ataacggtcc taaggtagcg aaattccttg tcgggtaagt tccgacccgc
      421 acgaaaggcg taacgatttg ggcactgtct caacaacaga ctcggtgaaa ttgtaattcc
      481 ggtgaagatg ccggatacct gcgacaggac ggaaagaccc catggagctt tactgtagct
      541 tgacattggg tcttggtact acatgtacag gataggtggg aggctttgaa accaggacgc
      601 cagttttggc ggagccatcc ttgggatacc acccttgta
//
LOCUS       DAEPUT010000218          600 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.224, whole genome shotgun sequence.
ACCESSION   DAEPUT010000218 DAEPUT010000000
VERSION     DAEPUT010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..600
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.224"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(45..560)
                     /locus_tag="KRL22_003943"
     CDS             complement(45..560)
                     /locus_tag="KRL22_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HBH1274323.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
BASE COUNT          181 a          126 c           56 g          237 t
ORIGIN      
        1 ctaaatataa aatttatgtt ttaaaatgta aaatttttat ttaatcaaag ttcaatatat
       61 tccacttttt ctttcgattc ttcaaaaaac cattcttcat tagaaaaatc accttctgca
      121 atttgtccaa taggcatttt catatacttt ccagttgctg tcactgctat atctccattt
      181 ggtagaatta tttctcctgt accttcaaat aattttctgt tttctttagt tattcttcca
      241 acaactttta tagtagcatc tgttggtact ggtttcttat atttcaactc taaagatact
      301 gttactcccc atatttggtc atcatttata cttacagctc ttccaatagt ctcatccaat
      361 attgcagcag acatacctcc atgaactctc ccaggataac tttgatgcca atcctttgta
      421 ttacaaattg atacaagctc tccattttca agttcataaa aatctgcttt aagtcctagc
      481 tcattttgtg ttccacaaac taaacaagat ttactactat tttgcttctt caaaacttta
      541 tactttgcca aaaaatccat ctcctaaccg acattagtag tcgcttaata ttaaataatt
//
LOCUS       DAEPUT010000219          508 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.225, whole genome shotgun sequence.
ACCESSION   DAEPUT010000219 DAEPUT010000000
VERSION     DAEPUT010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.225"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            205..>508
                     /locus_tag="KRL22_003944"
     CDS             205..>508
                     /locus_tag="KRL22_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1274324.1"
                     /translation="MIFTIIFYKKGRLCLLNLQSKWVNFLKPTYVSDEIKRKKLQVII
                     FFSITYGLSYSLGLLAICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNF"
BASE COUNT          211 a           41 c           67 g          189 t
ORIGIN      
        1 aaaaaataat agtaaactga ttgcataaaa atgattttta tataaaattt aagcagaaga
       61 ataaatttct aacgaaattg gatatttctt ctgtaaatac atattcaaaa aaagaattat
      121 aagagtttag tcagcagtcg tgtaagtaat aaggacttta taaatataga aatataatga
      181 tatgagtata agtagaaaaa ttttatgatt tttacaatta ttttttataa aaaagggagg
      241 ttatgtttgt tgaatttaca atcaaaatgg gtaaactttt taaagccaac atatgtcagt
      301 gatgaaataa aaagaaaaaa actacaagtt ataatatttt tttctataac ttatggttta
      361 tcttattcac taggtttatt agcaatatgt tttaatcatt taatagattc agaaatttta
      421 gctcaattta tgatgatatt gccattatct tcagtttcta ttgcaaaatt ttacacagag
      481 ggaagaaata atgataaata taattttt
//
LOCUS       DAEPUT010000220          483 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.226, whole genome shotgun sequence.
ACCESSION   DAEPUT010000220 DAEPUT010000000
VERSION     DAEPUT010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.226"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..>483
                     /locus_tag="KRL22_003945"
     CDS             <1..>483
                     /locus_tag="KRL22_003945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007037036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBH1274325.1"
                     /translation="TTLLEMINASEAREDDPEFQSPVDLMFERLEEKDPEHFAVRQYK
                     KFLLSAGKTRSSILISCGARLAPFDIKELRDLMEADEMELDTIGDRKTALFVIISDTD
                     DTFNFVVSILYTQLFNLLCDKADDEYGGRLPVHVRCLLDEFANIGQIPKFEKLIATIR
                     S"
BASE COUNT          124 a          124 c          118 g          117 t
ORIGIN      
        1 acgacgctgc ttgaaatgat aaatgccagt gaagcccgcg aggacgaccc ggaatttcag
       61 tcccccgttg acctcatgtt tgaacggttg gaggaaaaag acccggaaca ctttgccgtc
      121 cggcagtata agaaattctt gttatctgcg ggaaaaacac gaagctctat cctcatttcc
      181 tgcggtgcgc ggcttgcccc ttttgacatt aaggagctgc gcgaccttat ggaagccgac
      241 gaaatggagc ttgacaccat aggcgaccga aagactgccc tgtttgttat catttccgac
      301 accgacgata cctttaactt tgtcgtatca atcctttaca cgcagctttt caatctgctt
      361 tgcgacaagg cagatgatga atacggcggc aggctgcccg tccatgtgcg ctgtctgtta
      421 gacgagtttg cgaatatcgg acagataccg aagtttgaaa agctcatagc caccatacga
      481 agc
//
LOCUS       DAEPUT010000221          480 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.227, whole genome shotgun sequence.
ACCESSION   DAEPUT010000221 DAEPUT010000000
VERSION     DAEPUT010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.227"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..>480
                     /locus_tag="KRL22_003946"
     CDS             <1..>480
                     /locus_tag="KRL22_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007037036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBH1274326.1"
                     /translation="TLLEMINASEAREDDPEFQSPVDLMFERLEEKDPEHFAVRQYKK
                     FLLSAGKTRSSILISCGARLAPFDIKELRDLMETDEMELDTIGDRKTALFVIISDTDD
                     TFNFVVSILYTQLFNLLCDKADDEYGGRLPVHVRCLLDEFANIGQIPKFEKLIATIRS
                     "
BASE COUNT          124 a          123 c          118 g          115 t
ORIGIN      
        1 acgctgcttg aaatgataaa tgccagtgaa gcacgcgagg acgacccgga atttcagtcc
       61 cccgttgacc tcatgtttga acggttggag gaaaaagacc cggaacactt tgccgtccgg
      121 cagtacaaga aattcctgtt atctgcggga aagacacgaa gctctatcct catttcctgc
      181 ggtgcgcggc ttgccccttt tgacattaag gagctgcgcg accttatgga aaccgacgaa
      241 atggagcttg acaccatagg cgaccgcaag accgccctgt ttgttatcat cagcgacacc
      301 gacgatactt ttaactttgt tgtgagtatt ctttacacgc agcttttcaa tctcctttgc
      361 gacaaggcag atgatgaata cggcggcagg ctgcccgtcc atgtgcgctg tctgttagac
      421 gaatttgcaa atatcgggca gataccgaag tttgaaaagc tcatagccac catacgaagc
//
LOCUS       DAEPUT010000222          473 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.228, whole genome shotgun sequence.
ACCESSION   DAEPUT010000222 DAEPUT010000000
VERSION     DAEPUT010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.228"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            122..403
                     /locus_tag="KRL22_003947"
     CDS             122..403
                     /locus_tag="KRL22_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274327.1"
                     /translation="MASKQIPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
BASE COUNT          215 a           30 c           74 g          154 t
ORIGIN      
        1 gaaggaatat aaaacaagat tagaaaataa tagtgttact ttcataataa atacatataa
       61 agatattttt aagaataaaa tttattatta aataaaaaat aaaggagagt gatttaatag
      121 catggcatca aaacaaatac caagaaacaa tttagaaaag tttttaagaa taagagtctt
      181 atcacataca ggcgataaaa tacatataaa gttacctgta aattttgcaa agagaatgat
      241 tgagaataat gctttggatt tatttaatgg aaaagatgat gtagtagatg gtaaaaaagt
      301 tactgaaata ttagttaagg catttgacta tgatttaact ggagaagtag ttcacttgga
      361 gagaaaaaat ggagacatta ttaaagtttc aattgtacaa tagaattatt ttatatgaat
      421 tttatttttg aatagttata aataattaga aatttgtaaa aaagtataat ata
//
LOCUS       DAEPUT010000223          460 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.229, whole genome shotgun sequence.
ACCESSION   DAEPUT010000223 DAEPUT010000000
VERSION     DAEPUT010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.229"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            154..270
                     /gene="rrf"
                     /locus_tag="KRL22_003948"
     rRNA            154..270
                     /gene="rrf"
                     /locus_tag="KRL22_003948"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            276..364
                     /locus_tag="KRL22_003949"
     tRNA            276..364
                     /locus_tag="KRL22_003949"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Leu,seq:taa)
     gene            376..452
                     /locus_tag="KRL22_003950"
     tRNA            376..452
                     /locus_tag="KRL22_003950"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:410..412,aa:Ile,seq:cat)
BASE COUNT          145 a           88 c          103 g          124 t
ORIGIN      
        1 taactctata tttttaaact tgtcaaaact tatggatttt taatagtttt ataaggcaaa
       61 aaatcgaata aaaaaagtat tgacacaata agacaaagat gttattataa tacttgtctt
      121 agaaaaaaag ttaaatgaaa atttagacaa taatctggtt ataatagcag agaggataca
      181 cctgttccca ttccgaacac agaagttaag ctctctagcg ctgatggtac ttggtgggaa
      241 actgcctggg agagtaggac atagccaggt gatgtgccga agtggcggaa ctggcagacg
      301 cacaggactt aaaatcctgc gggacttacc tctcgtaccg gttcgattcc ggtcttcggc
      361 accacaaatt attgtgggcc attagctcag ttggttagag cgcccggctc ataaccggta
      421 ggtctggggt tcgagtccct gatggcccac cacaataatt
//
LOCUS       DAEPUT010000224          410 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.230, whole genome shotgun sequence.
ACCESSION   DAEPUT010000224 DAEPUT010000000
VERSION     DAEPUT010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.230"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            complement(142..342)
                     /locus_tag="KRL22_003951"
     CDS             complement(142..342)
                     /locus_tag="KRL22_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1274328.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT          147 a           69 c           37 g          157 t
ORIGIN      
        1 gttattttaa aaaagttagt ttaagtttga cgcttttcta aagtaacttc ttatttttgt
       61 aattaaaaat aaatataata aacaacaaaa aagagccctc gatagctcct tttctaaaat
      121 atatatattt aaattaaata attatattct atttacgttt tcagcttgag gtcctctatt
      181 accttgagtt atatcaaagc taaccttttc gccttcttct aaagttttgt atccatcatt
      241 ttgtatagct gagaaatgta cgaaaacatc atcttctccc tctacagata tgaacccaaa
      301 tcctttttca ttgttaaacc attttactat tccgtttttc attataagaa aacctccgca
      361 ttattaaaaa atacaaacta aaaaaataag tctgttctat taatataaca
//
LOCUS       DAEPUT010000225          378 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.231, whole genome shotgun sequence.
ACCESSION   DAEPUT010000225 DAEPUT010000000
VERSION     DAEPUT010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.231"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            182..298
                     /gene="rrf"
                     /locus_tag="KRL22_003952"
     rRNA            182..298
                     /gene="rrf"
                     /locus_tag="KRL22_003952"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            305..376
                     /locus_tag="KRL22_003953"
     tRNA            305..376
                     /locus_tag="KRL22_003953"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:337..339,aa:Asn,seq:gtt)
BASE COUNT          120 a           60 c           80 g          118 t
ORIGIN      
        1 atttatttga tgttattcat taagatatat gtgtagtttt tagagtgtta actctatgta
       61 aagtactaac ttcaattgat gaagtatata tcgtaaaaac aattactatt tagtacttca
      121 aaactattga catttaaaaa taaagatgtt aatataatac ttgtcttata aataggcaat
      181 atgtggttat aatagcaaag aggatacacc tgttcccatt ccgaacacag aagttaagct
      241 ctttagcgct gatggtactt ggtgggaaac tgcctgggag agtaggacgt agccacgtga
      301 atattccaag gtagctcaat ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
      361 agccccaccc ttggagcc
//
LOCUS       DAEPUT010000226          345 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.232, whole genome shotgun sequence.
ACCESSION   DAEPUT010000226 DAEPUT010000000
VERSION     DAEPUT010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.232"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
BASE COUNT          149 a           27 c           42 g          127 t
ORIGIN      
        1 tattaataaa aaagatatta cattaatatg aaaatatagg agattacaag tgtttgataa
       61 ttacagtaca tgttagatat atcattgtaa attaacatag ctttgaatat aataatgttc
      121 agaaggcaat atttttgagg tctgaatcca ataataatat agtcttatga ttgtagatat
      181 caaaaaatgt aagttactag gaatacgttt tgtagattta tatatgatta ataactaaag
      241 ctataaataa acaaaataaa aagagtatgt ttcaacctat agcttttaga tttaaaatat
      301 actcttttat taattatagt tgtataaatt aaccataata tataa
//
LOCUS       DAEPUT010000227          304 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.233, whole genome shotgun sequence.
ACCESSION   DAEPUT010000227 DAEPUT010000000
VERSION     DAEPUT010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.233"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..>304
                     /locus_tag="KRL22_003954"
     CDS             <1..>304
                     /locus_tag="KRL22_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002590471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase dimerization domain-containing
                     protein"
                     /protein_id="HBH1274329.1"
                     /translation="NVIQKIQQLVPPTHPVLGDGILVLTDIKSSPYPGASVVPDYCKA
                     TFDRRLLVGETREGVLAPIQALLDEMMKEDPELNAKVSYAVEKADCYTGNTIESER"
BASE COUNT          119 a           44 c           55 g           86 t
ORIGIN      
        1 ctaatgtaat ccaaaagata caacaattag tacctccaac tcatccagtt ttaggtgatg
       61 gaatattagt tttaacagat ataaaatctt ctccatatcc aggagcatca gtagtgccag
      121 attattgcaa agctactttt gatagaagat tattagttgg agaaacaaga gaaggcgtat
      181 tagctccaat acaagcttta ttagatgaaa tgatgaaaga agacccagaa ttaaatgcaa
      241 aagtttctta tgcagttgaa aaagctgatt gctatacagg aaatactata gaaagtgaaa
      301 gatt
//
LOCUS       DAEPUT010000228          299 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.234, whole genome shotgun sequence.
ACCESSION   DAEPUT010000228 DAEPUT010000000
VERSION     DAEPUT010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.234"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..>299
                     /locus_tag="KRL22_003955"
     CDS             <1..>299
                     /locus_tag="KRL22_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016281052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1274330.1"
                     /translation="CDTKGKTILISSHILSEISLLADDIGIIDHGTLLEEESLAELEQ
                     KSSKHIRFTLSDTAQAARILERTFHESHFSIQDDHNLRLHNLDLSVGKIVTAFVE"
BASE COUNT           98 a           58 c           58 g           85 t
ORIGIN      
        1 tgcgatacaa agggaaaaac aattttaatt tccagtcata tcctttcgga gatttctctg
       61 ctagcagatg atattggaat tatcgaccat ggcacactat tggaagaaga aagtcttgcg
      121 gaactggaac aaaaaagcag caaacatatc cgatttactc tttctgatac cgcacaggca
      181 gcaagaattt tagagcgtac tttccatgag agccatttct ctatacagga cgaccataat
      241 ttacgcttgc ataatcttga tttgtccgta ggaaaaatcg tgactgcttt tgtagaaaa
//
LOCUS       DAEPUT010000229          281 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.235, whole genome shotgun sequence.
ACCESSION   DAEPUT010000229 DAEPUT010000000
VERSION     DAEPUT010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.235"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            8..>281
                     /locus_tag="KRL22_003956"
     CDS             8..>281
                     /locus_tag="KRL22_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1274331.1"
                     /translation="MVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYTLLRPDGKT
                     MFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNP"
BASE COUNT          104 a           27 c           43 g          107 t
ORIGIN      
        1 tgataatatg gtttttgata ttgataattt aaaaggattt cttaatgata ccagttcatt
       61 tgggtttata gctaaagaaa ataataaaat tataggattt gcatattgct atacactttt
      121 aagacctgat ggaaaaacaa tgttttattt acactcaata ggaatgttac ctaactatca
      181 agacaaaggt tatggttcaa aattattatc ttttattaag gaatattcta aagagattgg
      241 ttgttctgaa atgtttttaa taactgataa aggtaatcct a
//
LOCUS       DAEPUT010000230          269 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.denovo.236, whole genome shotgun sequence.
ACCESSION   DAEPUT010000230 DAEPUT010000000
VERSION     DAEPUT010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.denovo.236"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..>269
                     /locus_tag="KRL22_003957"
     CDS             <1..>269
                     /locus_tag="KRL22_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1274332.1"
                     /translation="IKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASII
                     IGITLFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLIT"
BASE COUNT           87 a           38 c           41 g          103 t
ORIGIN      
        1 ataaaaatac taggacttat gatttcaaat ggacttatag ctttatctgg tagtcttatg
       61 gctcagttct tgggattctc agatgtaaat atgggtatag gaactttagt tcttggaatt
      121 gcctctatca taattggtat tacactattt aagaaattta cttttatcaa agatactact
      181 gcaataattg ttggctcttt tatataccaa ttcactatat actttgcaat gagtttagga
      241 atgttatcaa ctgacttaaa actaataac
//
LOCUS       DAEPUT010000231        43042 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.guided.030, whole genome shotgun sequence.
ACCESSION   DAEPUT010000231 DAEPUT010000000
VERSION     DAEPUT010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43042
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.guided.030"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            246..863
                     /locus_tag="KRL22_003958"
     CDS             246..863
                     /locus_tag="KRL22_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBH1274333.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTTDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIIKPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            971..3502
                     /locus_tag="KRL22_003959"
     CDS             971..3502
                     /locus_tag="KRL22_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1274334.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3936..4637
                     /locus_tag="KRL22_003960"
     CDS             3936..4637
                     /locus_tag="KRL22_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBH1274335.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4687..5769
                     /locus_tag="KRL22_003961"
     CDS             4687..5769
                     /locus_tag="KRL22_003961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1274336.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            6030..7130
                     /locus_tag="KRL22_003962"
     CDS             6030..7130
                     /locus_tag="KRL22_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG-Cd"
                     /protein_id="HBH1274337.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDILPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLISDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7127..7933
                     /locus_tag="KRL22_003963"
     CDS             7127..7933
                     /locus_tag="KRL22_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1274338.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7951..10089
                     /gene="vanT"
                     /locus_tag="KRL22_003964"
     CDS             7951..10089
                     /gene="vanT"
                     /locus_tag="KRL22_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH1274339.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10403..11023
                     /locus_tag="KRL22_003965"
     CDS             10403..11023
                     /locus_tag="KRL22_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH1274340.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(11189..11725)
                     /locus_tag="KRL22_003966"
     CDS             complement(11189..11725)
                     /locus_tag="KRL22_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH1274341.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11838..12512)
                     /locus_tag="KRL22_003967"
     CDS             complement(11838..12512)
                     /locus_tag="KRL22_003967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBH1274342.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            12715..14589
                     /gene="asnB"
                     /locus_tag="KRL22_003968"
     CDS             12715..14589
                     /gene="asnB"
                     /locus_tag="KRL22_003968"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH1274343.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(14681..16117)
                     /locus_tag="KRL22_003969"
     CDS             complement(14681..16117)
                     /locus_tag="KRL22_003969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH1274344.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKRSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            16446..17024
                     /locus_tag="KRL22_003970"
     CDS             16446..17024
                     /locus_tag="KRL22_003970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1274345.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            17063..17641
                     /locus_tag="KRL22_003971"
     CDS             17063..17641
                     /locus_tag="KRL22_003971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1274346.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            17727..18356
                     /locus_tag="KRL22_003972"
     CDS             17727..18356
                     /locus_tag="KRL22_003972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1274347.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            18346..21105
                     /locus_tag="KRL22_003973"
     CDS             18346..21105
                     /locus_tag="KRL22_003973"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH1274348.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            21192..22754
                     /locus_tag="KRL22_003974"
     CDS             21192..22754
                     /locus_tag="KRL22_003974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBH1274349.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEDI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            22755..23891
                     /locus_tag="KRL22_003975"
     CDS             22755..23891
                     /locus_tag="KRL22_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH1274350.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            23955..25031
                     /locus_tag="KRL22_003976"
     CDS             23955..25031
                     /locus_tag="KRL22_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBH1274351.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            25009..26247
                     /locus_tag="KRL22_003977"
     CDS             25009..26247
                     /locus_tag="KRL22_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBH1274352.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            26301..27389
                     /locus_tag="KRL22_003978"
     CDS             26301..27389
                     /locus_tag="KRL22_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBH1274353.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKHFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            27417..28208
                     /locus_tag="KRL22_003979"
     CDS             27417..28208
                     /locus_tag="KRL22_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBH1274354.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYTNIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKCDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(28323..28877)
                     /locus_tag="KRL22_003980"
     CDS             complement(28323..28877)
                     /locus_tag="KRL22_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH1274355.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            29073..30275
                     /locus_tag="KRL22_003981"
     CDS             29073..30275
                     /locus_tag="KRL22_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBH1274356.1"
                     /translation="MKSFVSPDNIWVLWAIVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            30331..31311
                     /locus_tag="KRL22_003982"
     CDS             30331..31311
                     /locus_tag="KRL22_003982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH1274357.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            31559..32512
                     /locus_tag="KRL22_003983"
     CDS             31559..32512
                     /locus_tag="KRL22_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH1274358.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            32502..33458
                     /locus_tag="KRL22_003984"
     CDS             32502..33458
                     /locus_tag="KRL22_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH1274359.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            33455..34210
                     /locus_tag="KRL22_003985"
     CDS             33455..34210
                     /locus_tag="KRL22_003985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1274360.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            34302..35267
                     /locus_tag="KRL22_003986"
     CDS             34302..35267
                     /locus_tag="KRL22_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1274361.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
     gene            35751..37610
                     /locus_tag="KRL22_003987"
     CDS             35751..37610
                     /locus_tag="KRL22_003987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1274362.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVGRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(37884..38483)
                     /locus_tag="KRL22_003988"
     CDS             complement(37884..38483)
                     /locus_tag="KRL22_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1274363.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(38586..39383)
                     /locus_tag="KRL22_003989"
     CDS             complement(38586..39383)
                     /locus_tag="KRL22_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1274364.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(39496..39601)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(39693..40679)
                     /locus_tag="KRL22_003990"
     CDS             complement(39693..40679)
                     /locus_tag="KRL22_003990"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH1274365.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYISKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            41163..42893
                     /locus_tag="KRL22_003991"
     CDS             41163..42893
                     /locus_tag="KRL22_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBH1274366.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
BASE COUNT        16567 a         4671 c         7281 g        14523 t
ORIGIN      
        1 caaaatgaac tttttagttc atgaggcact ctttttgtac gaaataaaat atatttttat
       61 tatttcaaca atgaaaaaga tgcttgtttc tattttgaga cagtataatt tttatgtaac
      121 tttaatttta gtaaatataa agttttaaaa ttgataaaat aggaggaatt tttaatataa
      181 aagggtaaat aaagggttta gagggcataa tatagaataa attaatatat ttaaggaggg
      241 tttttatgtg taaaaaaacg tatttattag tggtaagtat gcttatagcg ggtttattaa
      301 ctgcatgtag tgggagtcca actacggatt caggacaagc acaagataat acaaaaaagg
      361 aggcaaatgc atcaaataac gctttaaaag atgaaaaaaa taatgaaaat ttaatggaac
      421 aagattttaa agtgccatac acagatgcaa taaacatatt taaagataaa tataaggatg
      481 ctgatatagt agatttaagt cttgagagag atttaaataa atttgtttat actgtggaag
      541 gtgtagatga taataatgaa tataagatga aaattgatgc taatacaaaa gatgtattag
      601 aagataaaac agaaaagttg gattcagaag atttaaatgg agttgctaga aaagaaaaat
      661 tagatttaaa tgacataatt aaacctcaac aagctatgga aattgcatta aaagaacaaa
      721 atggaatggt taaagaatgg agtttagaca aagatttaga tgttactttt tataaaataa
      781 gaatagataa agataaaaat gaatatgaca taaaagtaga ttctaaaaag ggaactgtat
      841 tgaaggtaga aaaagaagat tagaagattt aaactatctt taaaataatt tcttttttga
      901 ataaattttg tttaaaatat aacaagcagg gtataaagag actaaataac tattttagga
      961 ggagtacggt atgtcattga aatcactaaa aataaaagaa aatttatatt gggtaggttc
     1021 acttgaccct gatttaagag tatttgacat aattatgtat acaccttatg ggactactta
     1081 taattcatat gtattaaaag gaacagaaaa aacagtttta tttgagacag ttaaagataa
     1141 gcattttgac aattatattg aaagattaaa tgatttaaat atagattttg aaaaaataga
     1201 ctatattgtt gtaagtcata ctgaaccaga ccatgcagga agcgttgaaa agcttttgga
     1261 tttagctaaa aatgcaaaag tagtagcttc agaaacagca attaaatatc ttaaggaaat
     1321 cgtaaacaaa gactttgaat atgttgcagt tacagatgga gatacattat caattgggga
     1381 caaaacttta gaatttttct ctgtacctat gcttcattgg ccagatacca tatacacata
     1441 tataaaagag gataaaactc ttgtaacatg tgattcattt ggtagtcact atagtaatga
     1501 taagatagta aatacacttg atgaaaatga agaaaaggat tacttggatg ctttaagata
     1561 ctattatgat tgtataatgg gtccatttaa accatctatg gtaactgcta tagaaaagat
     1621 aaaagattta gatatagata ctgtatgtcc aggtcatggt ccagtattaa ctgaaaatcc
     1681 tagaaaaatt atagaccttt attacaactg gagtgtaaat gaacaaataa agttagaaaa
     1741 agaagttaca atttgttatg tttctgcaca tggatataca aagattatgg cagaagctat
     1801 aaaagcatat attgaaaaaa atagcaacta taaagtaaat ttatttgatg taatagagca
     1861 taagcaagaa gatattttgg caaaaatagc agtatcacaa ggtgtattat ttggaacacc
     1921 aacaatatta ggagatgcgt taaagcctat atgggatata ttaatatcgt taaacccagt
     1981 tcttcatggt ggaaaagttg cttcagtatt tggttcatat ggatggagtg gagaaggtat
     2041 agaaaatgct atggagagaa taagtcagct tagaatgaca gcagtaaaac cttttgctgt
     2101 taactttaaa ccatcaaatg aagagattga taaattacat tcttatacag gtaaattcct
     2161 agataagtta aattctactt ttggaagtaa aaagaaaact aagaaattta aatgtgtaat
     2221 ttgtaatgaa gtttttgaag gtgatagtgc tcctagtgta tgccctgtat gtggagctaa
     2281 ggaagaccaa tttatagaag ttgaagaaga tgaagttact tttagaaaag atactgatga
     2341 atatttcgta atagtaggaa atggagcagc tggtttttat gcagcagatg ctataagaaa
     2401 aagaaataaa acttgtaaga taactatgat ttctaatgaa gatgagttga cttactatag
     2461 acctgcactt tctgatggta taaatgaaga acttggttca gatttctaca tggaagataa
     2521 agattggtat gataaaaata atatagtagt aatattagga acgaatgtag ataaattaga
     2581 tgaagtgaat aaaactatta tagtgaatga tggagctatt aaatttgata agcttgtaat
     2641 agctacagga agtagaaact ttataccacc aattaagggc catgatttag aaaatgtgtt
     2701 tactcttaga aatataaaag atttatatag tgtaaaagaa gcactagaaa aatctaagaa
     2761 agttgtagtg attggtggcg gtttattggg acttgaagct gcatgggaat ttagactaaa
     2821 aggattagaa gtagtagtag ttgaagccat ggatagcata ctatcaaaac aacttgataa
     2881 agaaggtagt aaaatattag aacaatgtgt aagagataca ggaatagatg taagattggg
     2941 tgtagcagtt gatggtattg aaggtgatgg aaaagctcaa aaagttgtat ttaaagatgg
     3001 agatagtgtc gactgtgata tggtagtatt ttcaattggt gtaagagcaa acactcaaat
     3061 ggttcaggat acatctgtaa aaattgatag aggtattgtt gtagataaga cattacagac
     3121 aaatgttaaa gatatatatg cttgtggaga tgttgcacaa gtgggaaata ttagtttagc
     3181 aatatggcca tcttcagtag aaatgggaaa aatagcaggg gcaaatgcaa gtggagataa
     3241 tttgacattt gaaagtgaag tatatccagt ttcattagat gcaatgaatg taaaagtatt
     3301 tagtattggt aatatacaaa attttgataa agaaatttca tcaaaagatg aaggtcaaag
     3361 aatatataaa aaattattta tgaaagatgg ttcattagtt ggagctatac ttataaatga
     3421 tttaagctgt actgttaaat tgataagatt aatatctgaa aaaggtgatt ttgaggatat
     3481 tatgaaggct gatatactat aatttaaata cattaaaata aaaaggagtt gtcttaaaat
     3541 tgattttttt ctaatcaaat tttaaattca actccttttt tgaattttta tataaaataa
     3601 catggaaatt ttagtaatgt ctgtggttac atacataggt ttaattgttt tttatatgga
     3661 ttgtctctgg tataataaat tgaattgtgt ttgactgata gatattttta ttgaaagtta
     3721 atacctgtta tgcgataata aggacgtgtt aggggagttt ttataataac aattaatctc
     3781 agtttttgtg ttccaatagt agcatcaaca cattctgatg tagtagttct tttcttataa
     3841 aaattagtta caaatatgct tgtaattatt tgatatgtaa atttaccaat attataaatg
     3901 atgacctcga taataaggag agtgaaaaat aatctatgaa cgaaaatatt ttgattgtgg
     3961 atgatgaaaa agaaatagca gatttaattg aagtatattt aaaaaatgaa ggttttacag
     4021 tatacaagtt ttatacaggt aaggaagctc tagaatgtat tgaatctaaa aatttggata
     4081 tggctatttt agatattatg cttcctgata ttgatggatt tcatatttgc cagaaaattc
     4141 gagaaaaata ctattatcct atcattatgt taacagctaa aattgaagat atagacaaga
     4201 taatgggttt aaccataggt gctgatgatt atataacaaa gccatttaac cctttggaag
     4261 ttgttgcaag agtaaagaca caattaagaa gatatatgcg atataataat tcttatgaac
     4321 aacagtcgat aattgttaat gagtatgata ttaaaggatt gattatcaat aaagaaacac
     4381 ataaatgtag tttatttggg aaagaagtag cattaacacc gattgaattt tctattcttt
     4441 ggtatttatg tgaacatcaa ggaaaagtgg ttccttctga agaattgttt gaagctgtat
     4501 ggggagaaaa atatcttgat aataataaca cagttatggc tcatataggg cgattgcgtg
     4561 aaaaaattca tgaaccttct aaaaacccga aatttataaa aactgtatgg ggagtaggtt
     4621 atacaattga aaagtaaaaa tattaaagtc aatcctgact ttactcaagt gagaaataaa
     4681 atttttatga gaacagcttt aatggcattt atagccatta ttttcatatg gattttatat
     4741 tcttttatat tgtatggtaa gttttctatc tggatagtat cattctttga aaatgctttt
     4801 cgtatggaat ataaagctgc attgaattta tatcagcaga ttttccgtaa tagcatggag
     4861 ctcttcatga tactagctat ggtgattgtg ttttttataa tattccgtgt ttatttaaat
     4921 tggtttacaa aatattttag tgaaataaat caaggtattg actctcttat caaagaagat
     4981 gttggagaag tggctttatc tccagagtta ttggcaatag aaaagaaaat aaactcaatt
     5041 aaacatatac ttgaacaacg taaatttgag acacaaatgg cagaacaacg taagaatgaa
     5101 cttattgttt atcttgcaca tgatttaaaa acaccactta catcagttat agggtatctg
     5161 acactacttc gagatgaaag tcagatttct gaagaactgc gaaaaaaata tttatctatt
     5221 tcgttggata aggcagagcg tcttgaagat ttaattaatg aattctttga aattacaagg
     5281 tttaatttat caaatatatc acttgaatac agtacagtaa gcttaactcg tatgcttgaa
     5341 caactaacat atgagtttaa acctactttg atgagtaaga atttaaaata tacactgaat
     5401 gttacaccaa atatgatgat aaggtgtgat gttaataaaa tgcaacgtgt atttgataac
     5461 ttattacgaa atgctgttta ttatagtttt gaagatacta ctattgaaat aacagctgta
     5521 caggaggatg attatataaa gcttaaattt atgaatcata gcaatacgat tccagaggaa
     5581 aaacttgagc gtatttttga acaattttac aggttggata catctcgtaa ttcaaacagt
     5641 ggtagagctg ggttgggact tgctatagct aaagaaatag tggagcttca taacgggaca
     5701 ataacagctc atagcgagaa caatataatt acctttaagg ttattattcc gattgtagga
     5761 aatttgtaag aatttaagta taaaaaaata ggaaattctt taggataaat aaataaagag
     5821 cactcttgtt attgatataa ttactgtatc aaaacaagag tgcttttatt ttgatacagt
     5881 aattatatca atagaaaaat gtgaaaatat attatgtgga acagatgcaa ttgtaagtga
     5941 aggttgattg gatttgaaat agaaaaagta ttttaacatg tttctgtaga ttgtataaaa
     6001 ataaataaat caacaaagga gaatcaaaga tgaataataa aaaaattgca gttatatttg
     6061 gtggaaactc aacagaatat gatgtatcat tacaatcagc ttttgcagta cttgagaatt
     6121 tgaatacgga aaaatatgat attctaccaa ttggaattac aagggagggt aattggtatc
     6181 attatattgg agattataat aatatccaga ataacacttg gtttgaaagg gatactgata
     6241 taattccagt tattgtttcg cagaaccgtg tcaaaaatgg tattattgaa tttttaattt
     6301 ctgatgctgt ttctcagaat catattccaa atagtgctat tgaatcatgt gaaaatgata
     6361 ttaaatacac taaacttgat tttgtatttc ctgtattgca tggaaaaaat ggagaagatg
     6421 gaacagtgca ggggttattt gaattggcag gtatacaggt tattggatgt ggtactcttt
     6481 cttcagcatt atgtatggac aaagacaaat cacataaact tgttcattca gaaggtatta
     6541 aagtaccaaa atcaatatta ctaaaatact cagataaatt taatgtggct gaactgtcaa
     6601 aagacttaac ttatccatta tttataaaac ctgtgcgtgc aggttcatca tttggtatta
     6661 gtaaaattta taaaaaagaa gagttacaag tagcagtaga cttggctttt gaacatgata
     6721 atgaagtaat aattgaggaa aatattgatg gttttgaggt agggtgtgca gttttaggaa
     6781 acaatgactt acttgttgga agagtagatg aaatagaatt gtcaaaagga ttttttgatt
     6841 atacagaaaa atatacattg aaaagttcaa aaattcatat gccagctaga attgatttgg
     6901 attgtgagaa aagaatacaa gagacagcaa aaattattta tagaactctt ggatgttctg
     6961 gatttgctag agtagatatg tttttaactc catctggtga aattattttt aatgaagtca
     7021 atacaattcc tggctttact tctcatagtc gttatccaaa tatgatgaaa ggtattggac
     7081 tgtcttttga agaaatattg gacaagataa ttgaggtgta cataaaatga tgaataatat
     7141 tttattagat aaaaataaag aagataaaat gacaaatact atcttattga ctaaagataa
     7201 agtttatgat gggaatctaa ttctagtaaa tgctttttta ccagttaaaa catctgaaga
     7261 tatagattta attcctgtag atacaaggtt tccaagtatt cttatgaaac gtgaagctac
     7321 aaacatttta caaaatattt taaaaagtat atgtggaata aatgaaatag tacctgtaag
     7381 tggatatcgt actgcagagg aacaacaaga tatatattca agttctctgc gtgacaatgg
     7441 aaaagacttt actaaaaagt ttgtagcact tccaaatcac agtgaacatc agacagggct
     7501 tgctattgat ttagggttaa agaaagaagt tatagatttt atctgccctg aatttcctta
     7561 taatggtatt tgtaatgagt ttcgtaaggc agcactacat tatggtttta tagagcgtta
     7621 tcagtgtaaa aaagaagaaa taacaggaat atctcaagaa ccatggcatt ttcgttatgt
     7681 gggatatccg cattctgaga ttatcaataa aatgaatctc gctcttgaag aatatataga
     7741 atatattaag agattttcgt atacaaattg tttaaaaata gaagataaag aaaaaattat
     7801 agaaatcttt tatgtaccta ttcatactaa agaagaagtg agaatctcta tacctgaaca
     7861 atgtgtatat caaatatcgg gtaacaataa ggatggtttt attgtgacat tttggagaaa
     7921 tagaaaggac taagaaatgg aggaacaaga atgattagga ataaatctta tgcagggctt
     7981 gattatttta ggattatagc tgcattactt ataattgcaa ttcatacatc tccattatta
     8041 tcatatagta aaatggctga ctttgtgtta actagtataa ttgctcgtat tgctgtgcca
     8101 ttctttttta tgctatcagg cttttttcta atttcaacat ataattataa ttgtaataaa
     8161 ctgaaatctt ttctaaaaaa tgtattattt atttacggga tagctattgt aatttatatt
     8221 cccttaaata tttacactgg atatttttcc atgaataatt tagtgcccaa tattattaag
     8281 gacattgtat ttgatgggac tttatatcat ttatggtatc ttcctgcatc aattattggt
     8341 gcaagtattg catactttct tgtaaaaaaa ctaggtttaa agtactcact agtaatcact
     8401 attgttattt atgtaattgg tatgtttggt gatagttatt atggtttttt agaaaaaata
     8461 ccactattaa agaatttata tgggtatatt tttgaagtat cagattatac acgaaatggt
     8521 atattttttg cacctgtatt tttcatactt ggtggaataa tatctaataa atctaattat
     8581 atgtcaacta aaaatagctt gattggattt cttatatcat tcttacttat gttatgtgag
     8641 ggaatgtttt tacataaact aggggtacag cgtcatgata gcatgtatat tatgttattg
     8701 ccatgtatgt atttcttatt tacagcctta acatttttga aaggttctcg agctaggtta
     8761 ttgcgaacat catcattaat tatttatatt atacatccta tgatgattgt tgttattcgt
     8821 atgttttcta aaatattcgg aatacaaact gtcttggttg acaatagcct tattcattat
     8881 atagtggtaa gtatagcatc ttttatagct tctataatta ttatattgat tcttaaacct
     8941 ctaaaaaaag acttgaaagg agaacataag gtaaatacca atagagcttg gattgaaatt
     9001 gatttaaata atttggaaca taatgtaaag atgatacaaa aagctatgcc agaagattgt
     9061 gaattgatgg cagttgtaaa agctaatgcc tatggtcata gtgcttttga agtagcgact
     9121 tgtgcaaacc aaataggtgt aaaagcattt gcagtagcaa caatagatga ggggattgat
     9181 ttacgtcgat atggaatact aggagaaata ttgattcttg gatatactaa cccaataagg
     9241 gcaaaggaac ttcataaata caatcttaca cagagtgtta ttgaccttaa tcatgctatc
     9301 tctttaaaca aacagaaata caacataaaa tcacacatta aaattgatac aggtatgcac
     9361 agactgggtt ttgatgttaa tgatgtgagg tcaattttaa aggcatttaa attaaaatac
     9421 ttagatatat gtggcatatt tacacacttg tgtgtttcag atagtctgaa agatgaagat
     9481 gtagacttta caaataaaca aattgaatgt ttttataagt taattgattt tctgttaaaa
     9541 aaaggtataa aaattcctaa agtacatatt caaagtagtt atggtttttt taattatccc
     9601 aatcttaagt gtaattatgt aagaattgga attgcattat acgggatatt aagttctcca
     9661 aatgatacga ctaaattgca acttgattta cgacctgttt tatccttaaa atcacaagta
     9721 attcttatta gaaaaataca aaaagatgat agttttggat atggaagagt ctttattgca
     9781 agcagagata gcgtaattgc tatattatct attggctatg ccgatggtat acctagaaat
     9841 ttatcctgtg gaaaaagtta cgtaataata aatggttgta gagcagcaat agtgggtcga
     9901 atttgcatgg accaacttgc tgttgatatt acagatatac ctaatgtaga agttggtaat
     9961 acggcaataa taataggaag agataattta tctgaattat ctgcttctga agttgcaaat
    10021 aactcatgta gtatatcgaa tgaattattg agcagagtag gaagaaggtt aaatgttata
    10081 aagaagtaac tcaattaaat agtaatattt gttgtactgt gtaatttatt ttactctgac
    10141 tagacatttt tagtaatatt atgtctaata tatatttttt ataacttaca tgacaattta
    10201 agttataaaa aggtgatgtt tcagattttt attttgaaac atcacctttt ttgttataat
    10261 atataataaa ataattatac cttaactgta aacttatata gattatttac tttttaatat
    10321 tagattcatt ttttgagatt ggtatataat aaacatatag agtatataat aatagttaaa
    10381 gttaaaaaag gggaaaagca atatgcagta tatacaagaa ctacttgatt tgactcaaaa
    10441 ttattgggtg ttagccacaa taatcggctt attaagtgca tttatagaaa gctttatacc
    10501 agccttacca cttgttgcta tagttacagc aaatgctgca atacaaggat tatttattgg
    10561 atgtttgtta tcatggattg gctcaggact tgggacaact tcattattct tattaataag
    10621 cagatttaat gatagtaagc tttttaataa gttgagaaat agtaaaactg aaaaagcaat
    10681 aagttggatg gataaacagg gatttaagtt attatttata gcgtatgcct gtccatttat
    10741 gcccggttgt ttagttacta tcgcatcagc ttttggtaaa aaagatttaa aagattttgt
    10801 gccagcaatg ttggcaggaa aatttgtaat gtttatagtt ataagttacg tggcaagtga
    10861 tatagaaggt tttataacaa gtcctttaaa gatagcatca tttatattat tggtgttttt
    10921 gtcatggaag attggaaata gagtaaataa aaatcttgaa aatcataatt atgatttcca
    10981 tcataaaaaa catcacaatg ataaagatga taaaatgatt tagcttgtac gaaataaaac
    11041 gtatcttaaa atgatttagt actaaattat tttaagatac gttttatttt ttgtattaag
    11101 gtacaaaatt tttagttctt ttgtaaacta aaatatataa aacttattta tacttagttc
    11161 aaaatattgt tatttatttt ttctacaact ataataaaat ataaaattga tatccaatca
    11221 aaaaaataac tatgaaattt aatagcttag atatgaattt ttctgttttt gagttagttt
    11281 ttataggtag taaagaaatg tttatggtaa tgggataaaa caattcaata ccttctttag
    11341 taataaggtc aagacacaag tgagatagat atcctattat aaacccactg gacaaacatg
    11401 agaaaactat attattgtta gtgaagattg tcagagattt aaaaaaacta taaataagta
    11461 ataaggcaat tagactgtga gtaaaccctc tatgtctaaa cctacttcca aataatttgt
    11521 atattaacat aaatttttta cttatgtaag aacctctcat atctatatct ggaaataaag
    11581 aacctaaata tgcaaaataa atataaatta taattaatac tattttatat gcaatatcgt
    11641 atttaactag gtatagattg tttataaagg ggagtatcaa aagtgcgaat atataacctc
    11701 ccctttcatg tgtttctttt atcatataaa aatcctcctg aatcgtcact ataaacatta
    11761 tattggtaaa tttagactat cttttattat attatatagc aaacataagt ttttttcaaa
    11821 aggattttaa tatttaatta atcttgagat tttaaatttt tgtaattttc taaagcacca
    11881 ttccaattta ctacattaaa ccagttgtca atgtattcat ttcttctatt ttgatatttt
    11941 aaatagtaag catgctccca aacatcaagt cctattatag gagttaggtt tttacttaca
    12001 gggctatcct gatttggagt agtcataata gataatttcc catctttagt agctacaagc
    12061 caagcccaac cagaaccaaa gacatctaaa gcagattttt ggaactcttg cttaaatttt
    12121 tcaaaagaac caaagtctct atcaatagct tcttttaaag attcagaagg tatggttttt
    12181 tctggcgtca ttatatcaaa aaagaattta tgattataag ctccacctgc attatttctt
    12241 acagttgtag caatatcttt aggtaaagaa tctaaatttt gcaataattc acataaagaa
    12301 taattataaa gctcaggata tttttcaaga gcagcattta atttatcaac ataagcttga
    12361 taatgcttat catgatgcag tttcattgtt tctttatcta tataaggttc aagtgcatca
    12421 tatgcataag gtaatggttt aaccttaaat ttgttatttt caggtgtaaa agcaaatgaa
    12481 gttatgcact gtgagattat aaataaagac ataataactg gtattaatat ttttttcttc
    12541 ataaaaatca cctcctaata tagtatttct agaaataaaa aaaatatgaa atattaacag
    12601 ataatttata agaatttaat agcaatttca ttttaaattg aataagtttt aaagccaaag
    12661 acaaaactat gaaatataga ataagactaa aggacagaaa ggaattttga ttatatggac
    12721 ggcaatattt caatttatta taaaggtgat atatctaaaa aagaagatat taaatttaaa
    12781 ataaaagaat ctgtaaataa tacaagactt tctagtagaa tagagtataa ggatgaggaa
    12841 aaaacttttg attttgaaag atttaatgta attgatgcta tttatggaaa taaaccattt
    12901 gaaaaagatg gaaaagttat tgtttttaat ggaaatatat ataactatca tgaaataaaa
    12961 gaagaattaa ttaaaaaagg acacaatttt actacaaatg atgatattga agtcttattg
    13021 gcatcttata tagaatttgg taagaattgt gtacataaga ttaaaggaat gttcaacttt
    13081 ataatctatg atagagaaaa tgaaagtata tttggagcaa gagatttatt tgggataaaa
    13141 ccactttatt atataaataa ggaaaatgca ataatttttt cctcagagta taagttttta
    13201 cttgaatata tgaaaaattt aaatataaat gaaagaagct tacaaagtta tttttcattt
    13261 caatatgtac ttcctgaaga tactatgata caaggaataa ggctgatacc agcaggtcac
    13321 tattttaggg tagaaaatgg tatactatct ttaaagagat ataataaact tgagtttaga
    13381 agtagtacaa aattttttta tactaaaaat cacttaggca atagagatgt gaacgaggat
    13441 gatataagaa atatagtagt agattcaata gtaactcata tggaagagga gaaagaaatt
    13501 ggaacatttc tgtctggtgg aatagattca tctattataa ctactgtggc ttcacaaatt
    13561 aatccaaata taaaatcttt ttctgcaggc tttagtgtca aaggatatag tgaattagag
    13621 gtagcaaaga aaacagctga taagttaggt atagaaaata tccagattaa tataacacaa
    13681 gatgaatata taaaatcatt accgaatgta atttattctt tggatgaccc tatagcagac
    13741 ccttcagaag taggtcttta tttcttaatt aaagaggcag gtaaacatgt taaagtagca
    13801 ttgtctggag aaggagcaga tgaattattt ggaggatata atatatataa agagtatagt
    13861 actatgaaat cagttgtcaa ttcacctact tatattaaaa gtatattagg aagagtttca
    13921 gaacttatgc caaacataaa aggaagaaat tatctttata gagctacaac accattagaa
    13981 aaaagatata taggaaatgc aaaagttttt gaaaacagcg aagtaaaaag attctttttt
    14041 aagtataagg aaaagaatat atatgaatac ctgttgtcta atttgtatag agatgcacaa
    14101 aaaaataatt acgattatat aagtaaaatg caacatatag atgtgaatac atggcttcaa
    14161 ggcgatatac ttcaaaaaat tagcaaactt tctacagctg agcaggttga acttagagta
    14221 ccatttttat ataaagatgt atttgatgta gcaaaaaatt taagaatgga gcaaaaaata
    14281 aataagaata atacaaaagt tttacttaga gaggcgttta gagaaatagt cccagaacat
    14341 gttgttcaaa ggaaaaaatt aggatttcca actccaataa gagtttggtt aaaagattct
    14401 ctaggggata ttgtaaagga aactatttat aattcaaatg tagatgaatt tatagataaa
    14461 aaatatgcaa taaaactttt agatacgcat cttaaaggtc atagagataa ttcgagaaaa
    14521 atatggacta tatttacatt ttgtctatgg catcaattat ttattgagca taaaaatgtc
    14581 gagtattaat actgttttca atattaatca gagggcaaaa acatgcaatg ttttcaccct
    14641 cttgattatt atggaatagg ataagtagaa ttttgattga ttagtttact atctcaataa
    14701 aattattggc aaatattttg acaagactac tttcaacagc taaatttaag ttttgtccat
    14761 catcatatcc agcggaaatc aatcctagta agtttccaaa catatctaaa agagctcctc
    14821 ctgaactacc actagagatt ggagctgtaa attgtatcat ttgaaccgtt tcaaaatcac
    14881 gaaaagctga aataattcca tctgaaactg tattaaaaag acctaaaggg cttccaattg
    14941 caactatttt ttgacctctc acaggttttt tactgacttt aacaggtatt ggcttgcatt
    15001 ttctatcaac ctttatcaca gctaaatcat aatctgaatg gtattttata atttggtaag
    15061 atgtataaac tttatcatca ttttcaaatc taactaaaaa tgaataccca tcattgacta
    15121 catgaagatt cgtaagtata taaccttcat tatttattac tactccagaa ccgctcttaa
    15181 acggtttatt ttcgttattg cacacaacaa tcataacaac agaagctgat aactttgcaa
    15241 ggtcttcata agaaagttct acttcctcat cttgtacaat ttttttagat gttagatttg
    15301 tgttattaag tgtattttta gagttaggtt tattcgtagt aggagaagtc ttattggtat
    15361 tttcactgta atttatattt gtaatatgcc tttcaaaagg tatttctaat atatttggag
    15421 tcttcctaga aagttcaaat agagtagaaa attttgaaca ttcaggatat aaatcaagaa
    15481 tatctttatt tggatttata tataaaatat cacacccaag ttgtgataaa aaatataaga
    15541 aaaaaagttc ttgcctttta atatttccaa agtatactat ctttggtgaa atagtagtct
    15601 tcaccttgtt ataaaataat ttaggtagaa aatagtccat ccaacacaaa agtttaactg
    15661 caaagttttt gatgatagag gatgtacaat ttggcatact tgtggaaaat aaatctaaag
    15721 tatttttaaa tgcaatcttt ttagtccaat ttaaggtgtc attttctatt ttacatggaa
    15781 agtcgatatt atataaatcc caactgttaa acttagaact attataaata ttaaaaattt
    15841 taagcatctt atctgtttgt tctttgtcaa aatttatttt tagattgttt aatctaatat
    15901 agggaattgt aggattatta aaaaaataag tatctatatt tttaattttt tctatgtatt
    15961 tatcaattga atcatcaaca cctatatatc ttgtaaagta gacttcttta atatatgaag
    16021 aacgcttatt tttataggta gtatcagata taaattcaat tagaggttca gttgactttt
    16081 ttattgaaat ctttaatggt ttaatagtac aaatcatatt ttttctccta taataagatg
    16141 atataatcta ttataaaaca acttaaaaca atatagtaca ataattttgt agtttcaaaa
    16201 taaaatatgt acttgtttat ataaatgata tataattaca tattaaacat agcttttata
    16261 catttaataa agtatgtaaa atctatgtaa aaagtaagaa atataaacat ttttttaatt
    16321 atattttaaa aatatcaagc aagttttctt cacaaatgaa taaaaaatgt tataatatga
    16381 ttaaagaaaa agataaataa ttagcaagat ttgtttagct aaaattaaca agggagcgat
    16441 aaattatggg tataacatta tcaaaaggcc aaaaggttga tttaactaaa ggaaatccag
    16501 gtcttaaaaa tattttagta ggtttaggat gggatactaa caagtatgat ggtggatttg
    16561 actttgattt agatacagca gcatttttaa caggagcaag tggaagtgtt actaatgatg
    16621 gagattttgt attttacaac aatttaaaac atacatctgg agcagttgag catctaggag
    16681 ataacagaac tggcgaaggt gatggagatg atgaacaaat agttgttgat ttatctaaga
    16741 ttcctggaga aataagcaag atttctttta ctgttacaat tcatgatgcg acagaaagaa
    16801 gacaaaattt tggacaagta agtaattctt atataagaat agtagataaa gacacaaatg
    16861 aagagttaat aaagtatgaa ttaggagaag attttagtat agaaacagct atagtagtag
    16921 ctgaaatata taagcacaat ggagaatgga agtttaatgc actaggttct ggctttgaag
    16981 gtggtcttgc tgcattatgt ggaaactttg gaataaactt ataatttcaa ctataacaat
    17041 aaactaaagg gggatatttt ccatggctat agtattaaaa aaaggacaaa aaatcgattt
    17101 aactaaggga aatccaggtc ttaaaaatat aaaacttgga ctaggatggg atacaaattc
    17161 atttgatagt ggctatgatt atgatttaga tgtaagtgtt ttcatggttg gagaatctca
    17221 aagagttgaa aaagatgaag attttatatt ctacaataac ttaaaacatc catctggagc
    17281 agttgaacac ttaggtgata atagaactgg tgaaggtgat ggagatgatg aggaaatatt
    17341 agtgaattta gagacaatgc caaagcatat acaaaagata gctgtaacag ttacaatata
    17401 tgaggctgct gaaagaagac aaaattttgg acaagtaagt aactcatata taagagtatt
    17461 aaattctgaa aatgatgaag aaatattaag atatgactta ggtgaagaat ttagtataga
    17521 aactgcaatt acagtatgtg agatatataa gtataatgga gaatggaagt ttagtgcagt
    17581 tggagcagga tttgaaggtg gcttagaggc actttgtaga aactatggct taaatgttta
    17641 atttaagcaa tataatatat taaatataaa taacctatac aaataatgta taggttatat
    17701 tatataaaat tttgtggagg tttagtatgt cgattaattt atcaaaaggt gataaaatag
    17761 atttaaaaaa atctaaccca ggactgagta acatacttgt aggtctagga tgggaccctg
    17821 tgcaacaatc tggaggaggt ttttttaaat cgttatttgg tggaggacaa gctgatatag
    17881 attgtgatgc atctgtattt atgcttaatc aagaaggtaa attaagtgga ataaaagatt
    17941 taatttattt tggaaatcta aaaagtgcct gtaaatcagt tttgcataca ggagacaatc
    18001 taactggtga gggtacaggt gatgatgaac aaatcctagt taatttggat aaagttccat
    18061 caaatattca taaattattg tttgtggtaa atatatacaa ttgtgtagat agaaaacaac
    18121 actttggaat gatagaaaat gcctatataa gagttgaaga ccaaggtaat aagaaagaga
    18181 tagcaaaata caatctatct gataattatt ctgaaaaaac tactcttata gtaggagcta
    18241 tatatagaaa agatggaagt tggcaattta aagcaattgg tgaaggaaca aaagatgcgg
    18301 gtcttaaaga agtaatgcaa aatttagaca ggattgagtg tgcatatgga atttaataat
    18361 gatatcaaat attataatgt agataaagaa gaagttacaa aagacttatc tgttaatcct
    18421 gaaaaaggtt tatcagaatc agaagtcaag actagaagag aaaaatatgg tttgaatgaa
    18481 tttactccaa aagaagaggg tagtttttgg gatgatttaa aggaaagttt aagtgaacca
    18541 atgatagtta tcttgattat tgcagcagta gtaagtgcag taattgggga aactcatgat
    18601 gcaataggga ttgtaggtgc tatagcaata ggtatagcaa taggtatgat tacagaaggt
    18661 cgttctaaga aagcagcaga agctctttct aagttgactg aaaacataga agtaaaagta
    18721 ttgagagatg gggaagtaca tcaaatttct aagagtgaat tggtaccagg tgatatagta
    18781 tatattgaaa ctggtgacat ggtacctgct gatggtagac ttatagaaag tataaacctt
    18841 aaaattagag aagatatgtt aacaggagaa tctgatgacg tatctaaaaa gtgtgatgta
    18901 gtagtttcta tggaagagat agaatctaaa ggagcagtag tagtacagga accaatacct
    18961 gcaaaacaga taaatatggt gtttggtggt acacttgtag cttatggtag aggagctcta
    19021 gttgtaactt caattggaga taatagtgaa atgggtaaaa ttgctcaaaa cttatcagaa
    19081 acagatgagc aaactccact tcagataaaa cttggaaatt taggtggttt gatagccaaa
    19141 gtttctagtg cagtagcagg attactattt atatttatgg ttttccaaat gataagtaag
    19201 aatgtattaa atgtagatat gtctggaata ttaccgtttt tagaatcaat agacccagtt
    19261 aaaacagcat ttacagtatg tgttgcgttg atagttgcag cagtgccaga aggtcttcca
    19321 actatgataa atatgacact tgcaataaca atgcaaaaaa tggctaaaat aaatgcattg
    19381 gttactaaaa aagaagcttg tgaaacgata ggttctgttt ctgtaatatg ttcagataaa
    19441 actggtacat taactgaaaa tagaatgact gtagaagttg catatgttga tggtagatat
    19501 attgaaagtt cagaagagga aataaatagt tattttgaag aaaactgtat gataaactct
    19561 acagctgatg tagagcacaa tgatggtgat attaagtatt taggaagtgc tactgaatgt
    19621 gcattgcttt tatattacaa aaacgtagat tatagacaag ttagaaaaaa ttctaatata
    19681 gtagctcaaa atccttttac ttcagattca aagagaatga cttctgttat aggtcaagat
    19741 aatcatcatg tactattatc aaaaggagca ccagaagtct tacttgaatt atgttcacat
    19801 attcaaagag gaaaagacat agttccatta actgaaaata taaaacatga gattttagaa
    19861 gaaataaaga aattgcaaat aaaatcaatg agaactttag ggtttgcata taaagaaatc
    19921 tcacaagctg aagaagaagc agcagtaact gctgaaagtg atgctatgaa tgtaagtgca
    19981 atggaaaata atttagtatt tagtggtttt gttggtataa gagacccact tagaaaagat
    20041 gttatagagt ctgtaaatac agcaaataaa gctggtgttt ctgtaaaaat gcttacagga
    20101 gataatataa atacggcaag agctataggt gaagagttag gcctattaaa aaataatatg
    20161 agagtggttg aagcttcata tatagatact ttagatgatg aagaattaaa acaagagata
    20221 caaagtattt caatcgtggc aagaagtaaa ccagatagta aaatgagaat agtttcagct
    20281 ctgcaaaaga gcggagatgt tgttgcagta acaggtgatg gtataaatga tgctccagca
    20341 ctttcaaaag cagatgttgg tatagcaatg ggtatatctg gtacagaggt atctaaaaac
    20401 gcagcagaca taattttaac tgatgatagt tttagtacca ttgtaaaagg tattaaatgg
    20461 ggtagaggaa tttatgataa cttccaaaga ttcgttcaat tccaattaac tgtaaatgta
    20521 attgcatttt tagtggctat aatatctcaa gttatgggac aagagatgcc atttactaca
    20581 atacaattat tatgggtaaa catcattatg gatggaccac cagcactagc attaggttta
    20641 gagccagtta gggaccatgt gttaaacaga aaacctgttg atagaaaagc caatataatt
    20701 tctaagtcaa tggtgtatac aatagtatta aatgcatttt atataacagc aatactaatg
    20761 ttacaatcta catttaattt cttaggagtt gatgaagcgc ataagggaac agtaatgttt
    20821 gcgttatttg cttttagtgc actgtttaat gcatttaact gtagagagtt taatgcagat
    20881 agtatcttcc ctaattttac acataacaaa ttagcactac aaataatagt gttgacagga
    20941 attgcacaag taatatttac tcagctattc caagatttct ttaactctgt agcaatggat
    21001 tttatgacat gggtaaaagt tttatgtgta gcagcaagtg taattgtggt taatgaagtt
    21061 gtaaaatgta taataagact ggtaaaacca aaaaagactg cttaaaacaa attttttaga
    21121 agaaaacaga ctgactcaaa atatgaattt tgggtcagtt ctgaataaac atttaaattg
    21181 ggaggatagt tatgggtgac tcaaaggtat ttgaaaaaat attctccagc caatcagata
    21241 gaggaaatta cactccttca aagggatatc taagttattt tatttcgtat attggtttag
    21301 aagatgaagt tttgtacaat ctcgagatat ttaagacaaa acaaaatatt gatagcaaaa
    21361 aagatattgc tttatttact gatgttatag caaatcctag tgattttgat attataaatt
    21421 attttaaaag tggacttcaa aaatatagaa ctagcatgga agatgtagat ataaatattt
    21481 tgggatttga agatattgat tataaaataa agcaagcaat ggatagagtg ttaaaagaag
    21541 aggaaaaaga atttactaat gatagagtta aacaaaattt tatagtgaaa ataatggcat
    21601 ggataaaaat ttatatcggt gctttagata taaataaaaa tgaagctcca aaagtaatat
    21661 tttatggaga tataaaaaaa catgaagttt atttactctt aatattatac ttggcaggtt
    21721 ttgatgtttt atatcttaat ccaaattcaa agagtaatat agatatttta aaatcagaaa
    21781 gatacaatat agagtttgaa gaagccaaca taatagaaga aaaaatttct tttgaagaaa
    21841 gggttatttt aggggaaaaa atagataaaa gttctgtaaa aaaagctttt actgttgggg
    21901 cagaagcatc aaagcgtata agtgaggaat tgttaaatga tgcaggattt ataaaacctt
    21961 ggcaactcca agatagaaaa ataaaaaatc tacttctaag ttcaactgtt gatgaaatat
    22021 caatatactg gaatcaacca cttaaattaa gaccaggatt taagtttaat gatgctattg
    22081 tagaagctcc aaattttctt tctaagatta atggaatata taacgataag aatgaatata
    22141 ttaagttttt agatttatta agagattcgg aaagttcaac atttattgaa tttaatggag
    22201 atgtagatag attttcaaaa gcttttacaa gagaagcttt tagtttatcc tttttattgg
    22261 attcaaaagg tgcaatagat aaaaactctg ttttaaataa taaagattat tccatatcaa
    22321 cactagcatt gaatcaacaa attatgattt tagagaaagt ggaagagttg ttagaaggaa
    22381 gtatgttttt gaatggttta agtggagaag acaagataaa aggtctattt acagtacttc
    22441 acatggataa gaaatttgtt catatgatga acaatttcga ttactcactt ataaacccaa
    22501 aattgattat atacatgtac aagagtattg tatttgataa agaaatagtt tttcttatgc
    22561 ttttacttag taagattgga tttgatatta tcatattatg tccaggagga gaaaacaata
    22621 tagagaatgt tataaataac caattgattg atgtacacag attggataaa atggtatatg
    22681 accttaaatt aaattcgctt gaaaatgata tacctttact taaaaaaatt tttggaaaga
    22741 ggagacgatt ttagatgggg ataaatataa atagtttttc aaaagataag aactctgtag
    22801 aggttactga gaatttgcct acagcagttc aagaagaaaa cttcgatata atggaatata
    22861 caaataataa aaaaaatgaa ctgagaaagt ctaaggaagt tgaggcattg acatctctta
    22921 tagaagtaga aaatccagat acgattttac agtttggtag gaaagcatct gaaggagtag
    22981 caagagtttc tgatagcctt ttaaatacaa taaaattaaa tagaaatgaa gaaaattcta
    23041 aaatgctggt tcatttaact aaaataatgg acaagtttga tttagacgat tttcaagaaa
    23101 ctaaggaacc aaatttcgtt caaaaacttt tcaaaaaagc taataatgcc attgaaatga
    23161 tgtttcaaaa gtatgaaaca ttgggaggag aagttgagaa aattcaaatt gagcttgaac
    23221 aatacgaaag agatatagca ctttctaata agcaaatagg tgctatgtta aatgaaaact
    23281 ttgagtttta caatgaactt caaaaatata ttgttgctgg agaaatggca atagaagaaa
    23341 tggataatga aatactacct ttctttaaac aaaaatcaga gactagtgga gaccaaatgg
    23401 atgttgtcaa ttatcaagaa ctattaaaag tttatgatat gttaaatcaa agagtatatg
    23461 atttaaggat agcagaaaat atagctatcc aaacaatacc tatgcttaga ggtatgcaac
    23521 ataataatta tggtttaatt agaaaaataa atagtgcatt tgtcgtaact ttaccagtat
    23581 ttaaacaatg tttatctcaa gctatattac ttaaaaagca agaattacaa gcaaaatctc
    23641 taaaagcact tgatgacaaa actaatgaat tattgcttag aaatgcacaa aatgtaagta
    23701 ctcaaagtgc acaaatagct agaatggctg gaacaagttc tgttcaaata gaaacattgg
    23761 aaaaaatgta caatactatc aaatctggta tagatgaaac tatgagaata gaagaaaaca
    23821 atagagcttt aattaaggat aatacaaaga gattggaaga attaaatacg actataattt
    23881 ataataagta gtattatatt aagggctaat ttgtataaag ttggcccttt ctatgtatat
    23941 gaggaggcta gacattgaaa tatttcgatt atatctgcaa agatgatttg gagagaattt
    24001 ttttgaagga gccagaagat tttagtgcta agactgaaaa agatgtgttg aaatatgcac
    24061 tgggcgcttt tttatacgtt ccagctactc aatataatat gatttataag agtattatag
    24121 gggatgttaa gggagttaga ccattagcta tttgtttaga agatgctgtt ggagtaaatg
    24181 gagagttgga ggccatagaa aatcttagat taattttaaa aaatattagc aatgaaagta
    24241 taactaataa agatggaata ccactaattt ttgtaagaat aaaagatgtg gagcaactgt
    24301 tgagaattaa agagattata attaaaaata gtcattttat aacaggaata ttaattccta
    24361 aagcaaattc ggagttaatt gaaaattgta tagaagcttt agattctatg aatcttcaag
    24421 atatgtatgt tattccgata gtagagacaa aagaatttat atataatgaa aaaaaagaac
    24481 ttagttttac taatttgtac aatgctattt taagacataa gtcaagaata ttaagcatta
    24541 gagtaggcat aactgatata ttagggatgt atggtataag gagagataaa aacttttcta
    24601 tatataataa tttgatttgt tcttcattta tattagatat aatcacatat cttcaaagac
    24661 cagagttaga tatacctata agtggtggag tatcagaatt ttttgatatg acgaataaag
    24721 atataagaaa taagtatata gaagaaatat tattggataa atatcatgga ttaattggaa
    24781 agaccgtaat tcatccaatg caaattcaaa ttgtacaagc gctatctaca gtatcatatg
    24841 aagattttac tgatgctttg gatatactgg atagtacaga cagtaagtat ggtgtgagca
    24901 agggtgtatt aggagagaga atgaatgaaa caaatccaca ttttttatgg gctaaaaaaa
    24961 cattgattct atctaaaata tatggtgtat taaataaagg agtagactat gaagaattgc
    25021 ttaaatttta attgtgagat tgacattatt gataatccat tgaatttaga actaaatgat
    25081 tttttagacg taggaataag aaataatagc aaaagacgtt ttttgtttat ctcaaagaaa
    25141 ctcggtaaac atttagcatg taagccaagt gagatggata atttgggaaa attaatggct
    25201 acaatttata atgaaaaaaa taaggaagaa tcaaatggta ctgttatagc ttttgctgaa
    25261 actggtacag ctgttgggca tagttttttt gattacttat gtggagatta tgaatttatt
    25321 catactacta gagagcagtt tgacgagtta gaaaatctgg aatttttaga ggaacattcc
    25381 catgcaacag accagaattt atactttggt atgcttaaca actttaaatt tggagatgag
    25441 ataatattgg ttgatgatga gattaccaca gccaatacat gcatgaatat aattaggaaa
    25501 attcaaagca tttatcctaa aaagaaatac actatatgct caatactcaa ttgggtaagt
    25561 gatgaaaatt taagtaaagt tactcgttta gaaagagagc tagattgtaa gatagatttt
    25621 gtatacttat ttaaaggaaa ctttaaattt tatatagatg aagatattat ttcaaattac
    25681 aacgataatt atagtattac taaattagag actatttcaa gtgataaagt aaatttagta
    25741 gtaaatcata tttatgttga tttagaagat tatattggaa ataagaaata tgtaaaatat
    25801 acaggaagat ttggaattaa tagaagagaa caatttagat taaaagaaat cgttaagaga
    25861 gaaagtaaaa aaataactat ggccagtaaa gaatctttaa aaaatgaaaa agaaaagatt
    25921 ctatttttag gtactgaaga atttatgtat atacctatgc tgtttgcaaa agaaaaagaa
    25981 aatcaatatg atatatacta tcattcaaca acaagaagtc caattattaa tattgataag
    26041 aataattatc ctattaaaag taaatttatg ctaaagagtt tttataatat agatattcaa
    26101 aattatattt acaatataga taaacataat ttttctaagt gttatttatt tgtagagctg
    26161 aataaaagtg aaaattctta tctagaattt attgatataa ttaaaaaaac aagtataaaa
    26221 gaattaacta tagtatgttg tagctaaagt gttttaacag gataaaatat atcacgattt
    26281 taagatagga gttgagtcat atgagagatt ttagcacgta ttctaaagat gatgttattt
    26341 ttttattaaa agatatatca aatttaattg aagaagaagg aaataaagaa agagaattaa
    26401 aaatacaaaa tggtagacat tattcagaaa tgataccaat agagtatgaa gttagtgaag
    26461 attatctgaa tttatatcat gagaaactaa gagaaaataa agataaactt gcattttcta
    26521 taggagttat gtgtgaaaaa ataattaaaa aaaatggaaa tgatgtagta ctagtttcac
    26581 ttgctagagc aggaacacct attggtattt tggcaaaaag atatataaga agcaagtata
    26641 atataagttt acctcactat acaatctcta taataagaga taagggaata gatatgaatg
    26701 caattgaata tatagtaaag aatcatccaa gttcaaaaat tcagttttta gatggatgga
    26761 ctggtaaggg aactatatca aaagaacttg aaaaagcatg tgatgaactt aatgttaaat
    26821 ttaaaaaaca ttttgactca acacttgctg tattagctga ccctgctgga tattcaggcc
    26881 tttatggaat tagagaagat ttcttaatac caagtgcatg tttaaattca accgtttctg
    26941 gtttagtaag tagaactgta ctaagagagg atttaattgg taaaaatgac tttcatggag
    27001 ctaagtttta tagacattta aaagataaag atgaatctat gaactatatc gaaactatag
    27061 aagaatgttt taaaaatcaa tttaagaata tatctgatga agttgaaaac tgggaaagtg
    27121 acattataac aagagatgga tactttgatg ttttaaatat aaaagaaaag tataacataa
    27181 cagatattaa ctttatcaaa ccaggtgtag gggaaacgac aagggtttta cttagaagag
    27241 ttccgtataa gattcttgtt aaagacttaa atgataaatc tttagaccat atattcatat
    27301 tagctaagga gaaaaatgtt gaagttgaac aaatggattt aaaagcctat aaatgttgtg
    27361 gaataataaa aaatatgaaa gatatttagg aaatatatta gacaggagaa tattgaatga
    27421 ttgttttttc agatttagac aggagtatca tttactccaa taaattttta aatgctgata
    27481 gtaaatatac taatatagaa atttataggg aaaaagaaat atcttatata tctttagata
    27541 ctataaattt aataaagcaa atacaatatt atggtatgtt tatacctaca actactagaa
    27601 cagtggagca atttaagcgt atagaattta ataaatatgg gatttatttt ccttggagta
    27661 taacttcaaa tggaggagtt atacttaaag ataatgaaat attgaaatca tggagtgaaa
    27721 aaatagataa actaaaatgt gattatgagc ccattgaaag tatgattcat aaatttaaag
    27781 actatttgaa tgtagatgga ataactaatt ttaaagttgc agaagataca tttttttata
    27841 tagttgttga tttatcaaga tttaatttgg attcaatcaa agaatataca aatatattgg
    27901 aatcaaaaaa ttggaagttt tatgtgagtg gcagaaaaat atattttata ccaaaagaaa
    27961 tttcaaaaga aaatgctata aaatacttga ctaaagaatt aggaatagaa tatttttatg
    28021 cagttggaga ttctattatg gactatggta tgcttaatat ctcaaataaa tcctatgtat
    28081 tgaagcatgg tgatataaat aaaaatgaaa tagaaaattc atttatatca agttctttca
    28141 atggaatgag tggaactgaa gagatactat ctaacatttt agacgagaac tgcctactta
    28201 acatataatg actgatatat aaataataaa ctagaaaaat ctgaaataaa ttatagtaaa
    28261 gtttatcata ctaatttatt tcagattttt atcaatttat atttaagtaa gaactcaata
    28321 tgttaaaatg aaggtggagt cattgcccag actgagatac atacctcatc atcataattt
    28381 tcatacacat gtggtatagt actgttaaaa taaaaactat ctccttcctc caatagatat
    28441 tccttatttc caagtgttat cttcatttta ccttttatta tataaccaca ttcttctcct
    28501 tcgtgtgtca caaattcact gtttttttgt gtatgaccat ctagcgtaac aagtataaat
    28561 tctatttttt tcccagataa attaggaaca agaagttcat aaaattttgt agaatcatta
    28621 gttactattt tttttcgatt atttttcttt actactatat cagagtcttc tcttccaatc
    28681 tcttcaaaaa aataacctat atttatatca agagcttttg atattttcca cattgctaca
    28741 atagatggaa caaccatatt acgctcaatt tgacttatta agcctgtact taaatctgaa
    28801 ttttttgcta aagtagagat acttatattt ttagattttc taagagatct aattttgctt
    28861 ccaacatcta tattcattag atacaaaccc cctcagacat gattataaca tataatttat
    28921 aaagattaat aaaataaaaa aaaagtttta caatacaagt attttttatg ttatattgaa
    28981 ttttctgaaa agatgcatta taatagtatt aatattcaat atattgaata ttgataacga
    29041 tattttaatt taatgaaatg gaggtagtta agatgaagag ttttgtaagc cctgataaca
    29101 tttgggtatt atgggcaatt gtaactggat gggcagcatt tagtatttac ttggaacaaa
    29161 agtacaattg ggcatcaaaa gtgtctggag caataatagc tcttgtagga gcaatgttat
    29221 tatcaaatct aaatattata ccagtagagt ctgttgtata tgaccaagta tggggatatg
    29281 ttgttccttt agccatagct ttattgttat atcaatgtaa tattaaaaag atatggaaag
    29341 aaagtggaag attgctcatt atatttcttg taggttctgt aggaactgta cttggagcta
    29401 tgattggatt tttagcatta aaaaatgtag taccagattt aaatattgtt gcagctatga
    29461 tgacaggttc ttatataggt ggaaatgtaa actttgctgc tatgtcaggg gcgtttgatg
    29521 cgccaggaga attagtatca gcaacagttg tagcagataa tcttttaatg gcattatatt
    29581 tctttgtctt aatagctata ccatcaattg gattttttag aaaacatttt aaacatccac
    29641 atgtagatga aatggaaagt ataggtataa ctgaaggaga aacagtagca gcaaattatt
    29701 ggggaagaaa agaaatatct ttaaaagata tagcaatagc cattggtagc gcttttataa
    29761 ttgttgcagt atctgtagaa ctatcaactt ggtttaaagc tataatacca ttatcaaatc
    29821 cttttttagc aatgttaaat actttatttg gaaatcaata tctaataata actactttga
    29881 ctatgttgtt tgccacattt atgcctaatt tctttggtga tataaaagga gcacaggaat
    29941 tgggtacatt tttaatatac atattctttg ttgtagtggg tgttcctgct tcaataacat
    30001 taataattca aaaatcacca ttactacttt tatactgcgg aataatggta ctaataaaca
    30061 tgctagttac gtttatagtt gcaaaaatat ttaagtttag cttagaagaa gctattcttg
    30121 catctaatgc aaatattggt ggacctacaa cagcagcagc tatggcaata tcaaaaggat
    30181 ggtctaagct agtaggacca atacttatag ttggtacatt tggatacata gttggtaatt
    30241 attttggtct tttagtagga aatattttaa tataatttta cgtgaaaaaa agttgttttt
    30301 tagaaggatt ttatttaatt ggaggttgtt atgattttcg atggacattc agatacttgg
    30361 gcagatgtaa caataagaag gcttaacggg gaaaaagatg tatttagaag aatccatctt
    30421 gataatttta aaagagcaaa tatagaagga gctatttttg taatatggat agacccacca
    30481 tatgataaag agcctgaaaa aagagttaaa caaattataa gctctataaa agatgaaatt
    30541 gaagatatga aagatgttgt aaacatagta aaaaaatatt cagatataga taaaggtata
    30601 agtgaaaaca aaataaatat tttaattggt cttgaaggat taagccatat tggaagaaat
    30661 atagatttat tagattattt ttataaagaa gttggtgcaa gacatgcatc attaacttgg
    30721 aatgaacaga atgaacttgc tacaggatgt ttaggggatg aaaatcgtgg tttaactgaa
    30781 ataggtaaaa aagcagtcaa taaaatggaa aaattgggca tgatagtaga tgtgtcacat
    30841 ttaaatgaaa aatcattttg ggatttaatg tctgttgcaa gtaagccagt tatagcttct
    30901 cattctaatg ctaggagttt atgtgatgct aaaagaaatc ttacagataa tcaattaaaa
    30961 gaaatttcaa atacaggtgg attagttgga ataaatagtt ttagaggatt tactaatagt
    31021 aatcctaaga agcaagattt aatacatttg gttgaccata tagactatat ggtaaatctt
    31081 ataggtatag aacatgtatc ttttggtttt gattttagtg attacttagg gaaagagact
    31141 ataggttctt ttactggaaa tgctagtgtg ccaagtgtag atggtcttga aagcacacat
    31201 acagcacaga acatagtagt agagcttgaa aatagaggtt ataaaaagaa agatatagag
    31261 ttaatctcta gtggtaattt ttataggctc tttaaagata tactaaaata atataataaa
    31321 gaacttaaat ttataaaata gtatatttat acaaataata tctacatatt taaattggcg
    31381 ttcataattt attaaattaa attttaatgt tactagaagt ttcaattcta gtaacatttt
    31441 ttatgttaaa aacagatata gatatgtatt gacaatgata attattattg ataaactatt
    31501 aaagtgaaaa tgataataat tttcagttta attaataaaa gatttttaag gagggagaat
    31561 gaagaaaagg tatttagtca taggaataat aattttgtct tatttttctt tatttatagg
    31621 agctgaagat ataaatataa tgcatatatt tgccaaaaat cagcataaac ttatgatatt
    31681 tatcatgagt agaataccaa gattaataag tatattgatt gctggtgtag gaatgagcat
    31741 agcaggtctt ataatgcaac agataagtaa gaataaattt gtatcaccta caacaggtgc
    31801 tacaatagat gcagcacaat ttgggatagt aatatgtatg cttttagtac caactgcctc
    31861 tatttttaca aagacaataa tagcatttgt attttctctt gtagggactt ttacgtttat
    31921 gaaaataata gggaagttac aatttaaaaa tataatcttt gtaccattag taggtataat
    31981 gtttggaaat ataataggtt ctatgacgga ttttatcgcg tataaatacg atttgagtca
    32041 aaatgttagt tcttggatgc aaggtgactt ttctatgata cttaaaggaa attatgagat
    32101 attatatatc acaatacccc ttataatatt agcatatatt tatgcaaata aatttactgt
    32161 tgttggtatg ggtatggatt ttgcgacaaa cttaggtctt agttacaaaa gaattgtcaa
    32221 tataggtctg ataatagtag cacttgttac agtatgtgta gtcgttacag ctggtaatat
    32281 cccttttata ggtctaatag ttccaaatat cgtatccttg tatatgggtg ataatataag
    32341 agcaagcata tggtatactg gtttacttgg agcgatattt gtacttatat gtgatatttt
    32401 tggaagaatt attatttatc catatgaaat atctataggg cttacagttg gagttatagg
    32461 aagtatacta ttcctttatt taatattaag gaggaatgtg aatgaagctt agtctcaatc
    32521 aaaaaattta ctttgtaagt atattactat tcatatcaat agcacttttt ataatttatg
    32581 gaatagacat gaatcattta gaatatgcat tatcacaaag aataccaaaa atatttgcta
    32641 tggtattagg tggaggatgt atagcattta ctactgtagt gtttcaaaca attacaaaca
    32701 atcaaatatt aacaccaagt gtactaggtt tagattcatt gtatgtaatg attcaaacta
    32761 taatagtatt catatttggt tcaagcagta gtctgattat aaatgaaaat tataatttta
    32821 ttattaatgt agctatgatg attggagctt cattgttatt atataagacg ttatttgaaa
    32881 aaaataaaaa taatattttc tttttaatcc tagtaggaat gatatttgga accttattta
    32941 aaagtgcaac aacatttatt caggtaatga tagacccgaa tgaattttta gctttacaaa
    33001 ctagtataat ggcaagttta aacaatataa acactaatgt attgttaata gcatttataa
    33061 taattattgc cataatacct tttatatatg atgaaataaa gtatttagat gtattgtcgt
    33121 taggtaaaga acaagcaatt aatttaggtg tagattttga taaagcagtt aaaaaaatga
    33181 taatattaat agcaatttta gtctcaatat caacagcact tattggacct atgacatttt
    33241 taggactttt acttgctaat ataacaagag aaatttttaa aacatataag catacatact
    33301 tgatttcggg ttctatgttg atagggatga ttacattgat aataggtcaa ttttttatac
    33361 aacatgtatt taagtttgat acaactttaa gtgtagtaat aaattttata ggaggaattt
    33421 actttattca attactatta aagggggcaa atagatgata gagataaaaa atatatttaa
    33481 aagatataag aataaaaatg ttgtagatga tgtctctttt agtatagaaa agggaaagat
    33541 aacatctttt ataggaccaa atggagctgg aaaaagtaca gtactatcaa tagttacaag
    33601 acttatagga ggtgatggtg gagaagtaat aatagaagga aaaagcttga ctaattatag
    33661 caataaagaa ttagcaaaaa aaatagctat tcttaaacaa tctaacaata taactttaaa
    33721 gcttacaata agagaattag ttggatttgg aagatttcca tatagtgaag gtaatctaac
    33781 taaagaggat gaaaattata ttgatgaagc aatagaatac atgaagttga ctgatataca
    33841 acataagtat ttagatgaat tgagtggagg tcaaagacaa agagcttata tagcaatggt
    33901 aatagctcaa gatacagagt acatattact tgatgaacca ctgaacaatt tggatatgaa
    33961 ccattccgta cagatgatga aggtacttag aggtctttgt gatgagttag ataagactat
    34021 agtattagta atgcatgata taaattttgc atcatgttat tcagataata tagttgcatt
    34081 aaaaaatgga aaagttgaaa aagtaggtcg tacagatgag atagtaaatg aaaaagtttt
    34141 agaagatatt tatgagatga attttaacat taagaatata aatggaaatc gaatctgtat
    34201 ttatttttaa aatattgtat atgaaaataa acttgctata tgatttttta taaagttttt
    34261 aaattaaaat aaagattaat aggagagagg aaaatattga tatgaataaa aaagcagcaa
    34321 tagtagcagc agtagctatt ataggattag tgacagtgtt tgcattaggt ggaagtaaaa
    34381 agaatgaatc aaaaacatca gaaaactcaa ataatactat gaagataact cataacttgg
    34441 gagaaacaga tgtaaaatta aatcctaaaa aagtagtagt atttgattat tcggctttag
    34501 atacaatgga tgcattaggt gtagctgaga atttagtagg acttccaaaa gcgagtttac
    34561 cagcatcctt agaaaaatat aaggatgaca agtatgcaga tttaggagga ttaaaagaac
    34621 cagatttaga gggtataaag tcggcaaatc cagatttaat tataataaat ggaagacaag
    34681 aagattttta tgagcaattg tcaaaaatag caccaacaat aagtacaagt aaagatgata
    34741 agaagtactt agaatctgtt aaaaataata tagacaaaat agcaaaaata tttggagtag
    34801 aagaaaaagc aaatcaagaa tttagtaaaa ttgaaaagaa aatagaaact ttgaataaaa
    34861 aagtaacaga taaaaattta aatgctttaa ctataatggt aaatgaaggt aatttaagtg
    34921 tatttggtga agaatcaaga tttagtatat tatacaatag ttttggattt gaaaataaag
    34981 ataaaaatat aaaagaatca agtcatggac aaaatattac ttttgaatat atagctaaac
    35041 aaaatccaga agttatgttc gttatagata gaggaatagc tactggcagt gatgtaaaag
    35101 aaagctcaac tgcaaaatct gttttgaaca atgatataat aaaatctatg gatgcatata
    35161 agaatgataa tataatatat ttagattcac caacatggta tgtaaatgat ggtggtctaa
    35221 catctttaaa taaaatgata gatgatgctt caaaagcggt aaattaataa tccgatataa
    35281 ttaatcaaaa tgtatttttt ataaaatgat tatcaaataa actaggagtt tttaagaact
    35341 cctagtttat tttttgcata aaaaagatgt agtttaaaca ataatattat ctataataag
    35401 ataaatctat tcaaaatcta ataaaatgtg aagttatact agacaaaaag aataactctt
    35461 aaatataatt aagttatata ataatatata attataatga tataatttta ataggtggtt
    35521 tgtaattaaa aagtttataa attatattaa tagtaataat ctataagaac ttatatatta
    35581 gaaaaaaatt tttgtatata tagaggactc taaagatgaa ctatgtaaaa caaggtttat
    35641 atattctaat tgtatagaaa atttattgta aacacatgta tattattaga aaaaatagtt
    35701 tgaaggtatt caataaacat aaaaaacaat ataggggata aaggtgtttt atgaagagat
    35761 ttttgaggag aattatctta gttttattta ttttgttgat ttttataagt tttatttcta
    35821 ttaaattaat tcataatgtt ggagattatg gaaaattgat taattatgtt gggattgttc
    35881 gtggagctag ccaacgtcta actaaactag agatgaatca tcaaccaaat gatgaattaa
    35941 tagaatatat tgatgaaatc ctacaggagt tgattacagg gcatggagat tatggtttag
    36001 taatcactga ttgtaatgaa tacaatgagg acttactttt attagaaaaa aagtgggaag
    36061 atttaaatat tgaaattaaa aaagtaagaa tgaaagaaca gaataaccag ttattaagta
    36121 taagtgaaga gtttttttct cttgcaaatg atacagtgtt taaaatagaa aacttttcta
    36181 aagaaaaaag taattactta atgactttaa taataattat atctattata ggtatattag
    36241 catgtatcat attgatttta caatatagta aaaaaatggt tagactggaa aaattaaatg
    36301 tagatttaaa aaatattgca tataaagatg aactaacagg agtaaatact atagaaaaat
    36361 ttaaattgga tgcaaatcaa aatatttgta tacataagga taagaaattt gctgtattct
    36421 atattgattt tgaaaacttt aaatacatta atgatatatt tggatatgat tatggtgaca
    36481 tgatactgaa aagatatgct aatcttatga tgaatgacat agggaaatat gaaatatttg
    36541 caagagaaat tgcagataga tttgttgcgt taagatgcta tgtagataag gaagatttag
    36601 tgggaagaca acgagatgta gacaatgaac taattaatat aacaaatgaa attaaaaata
    36661 aacatagtat tactgttgtt agtggaattt gttgtattga agatgtaaat gaaaaattaa
    36721 gtatagatgg tttaataaat agagcaaatt ttgcacaaaa aactgttaag aataaaccag
    36781 gtactaatta tgctttttat aatgacagta ttcgtaaaaa aatgattgaa gaaaatacta
    36841 tcaagagtag aatacatgaa gctattgaaa aaagagaatt tatagtttat ttacagccta
    36901 aagttaattt acatagtcaa aaaataaatt gtgcagaagc tttagttcgt tggcttactc
    36961 cggataaagg tattatatcg ccagcaatat ttattccagt acttgagaag aattttttta
    37021 ttgccttagt agataagtat gtttttgagg aggtttgtaa atggattaga aagaggttag
    37081 atgaaaataa accttttgtt cagatatcag ttaatgtttc aagaatacaa ttttataaca
    37141 ctaaatttgt agaaacttat tccaatatac aaaataaata caggatacct aaaaatacta
    37201 tagaaattga atttacagag agtgttgctt ttgagaatca aaaacatctt ttggaaatta
    37261 tacatgattt gcatgaaaat ggatttactt gttctttaga tgattttgga aaaggttatt
    37321 cgtctttaag tgttttaaaa gatttaccat ttgatgtttt aaagcttgat tctatgtttt
    37381 tcaaggctag tttagataaa gataaagaga aaatagtaat aaaaaatatt gtacatatgt
    37441 taaaagaact taatatcaca actgttgctg agggcattga atgcaaggaa caagttgaat
    37501 ttcttaggga tattgggtgt gatttagttc agggatttgt attttataaa ccaatgccaa
    37561 tattagaatt tgaaaaaata ttggataaag agtttgttta taatagctaa aatgtacttt
    37621 ataaaatatg aactaattaa gtaaaattat tttgtactga ataaattttt actttattta
    37681 cagaaaatcg cgaaaagtgt attcctttaa gtgtgggatg gatagcacaa atagaggaga
    37741 aaaaatattg gccatataag aatgcataat aatataaata tttgaaaggt cagcatcata
    37801 taaaaattaa aaagaaaata aataattttt ctataaaaaa gagactatga gaaaatttac
    37861 tcatagtctc ctaaataatg tatttatttt cttcctgcaa cccattttaa tccccaatga
    37921 aattcagtat ccatttctct atgacctttg aagtatttaa ctactttttc aacactgaat
    37981 gtctcatcat ttacattttc tatcaatgct attgaacaca tattatagcc atttttatgt
    38041 tcatcaagtt tgacaactaa gtctgaatct tgtttttgtt tgattgttac aattccatca
    38101 gcttcagacc agttagctac accttcgtat ataaaagcat aaataagtat tctttttata
    38161 tcttttattt tattaccatt tattcttaaa ttttctcctt gtgtattact tcctgttctg
    38221 tcatctccat ctaattgagc aaaaggtgga ttgtctaaac taccaaaggc atttcctaat
    38281 gcttgaacag caccttttac accatttttc atctcaaata ggcaacccaa atctaaatct
    38341 atattactgc ttcttaaaga gccaaaaaaa cccttttttt gtactttttg attccaattt
    38401 aaattaacta agatttcacc taaatcgcta ttttcctttt ttgtaaggtt tattttttgt
    38461 ccctttttta attctatagc catagtaatc ttcctccaca aacatagatt tatttaaatg
    38521 gtagcactta ataagtcaat attcaacaag attagaataa taatattaaa attatactaa
    38581 atatactaaa aagtaggaat cacaatacct ttgtattttt cttcaattaa gcttcttgct
    38641 ttatctgatg taagaacatc ttgtagaact ttaatctttt cactgtcttt atcttcagtt
    38701 ctaaatgcta aaagatttgc atactcgtca tttataggag ctgtataaat tccgtttttc
    38761 ttggcatcaa gaccagcagg tacagcataa gtagtatcta taaatgcagc agtcacatct
    38821 ggaagagaag atggaatttg agcaatatct aactctttga attgtattcc ctttggattt
    38881 tctattatgt ccttaggact aactaatcca tcccctttag gtaacgttaa aagtccaata
    38941 ctttcaaggt atctaaggtt cttagaacaa gaagatgggt tattgcttat tgcaattgta
    39001 tctccttttt taaattcatc aacagatttt atcttataag agtaaagtat tgctgggcat
    39061 acatatagtt ttttaccagc cattattttg taacctttgg ccttaacagc ttcttttaga
    39121 taaggttcat gttgaaatag atttgcatca atttcaccat tatttaaagc ttcgtttgga
    39181 agtatgtaat catcaaagtt tttaacttct aaagtatatc ctttttcttt aataagtggt
    39241 tttaattctt ctaataactc tcctcctgga actaaagtag caccaacaac aattttttta
    39301 tcatctttag ctttagaaca tccaaccaca gctaaagtta atactagaca taataacaaa
    39361 cataataatt ttttgaattt catataaatt ccctcctgaa tataattgat tagttaaaaa
    39421 taaaatacca ttctttatca cactgcaaaa taaaaataag cctgagttta aactcaggct
    39481 ttaaaagcta atttagactc atctttcagt ataatactgc aggatttagc accaatgtat
    39541 ataaaaatat actggttgct gggtttcata gggccagtcc cttcaccact ctggataaga
    39601 agtatcaatt tttaattatg ttataaatat tatcatgatt ttttacgtct gtaaacataa
    39661 ttttataaat attttaaaat ctttaatgta ttttatttaa cacctaaaat tccagaaact
    39721 agaatatcag tatcagcacc taagaaatag tcatttattt caatagaatc cagagtattt
    39781 ctcaaagcat tttcttcatg ccttatacca ataagtttat tttctacaaa tgcaacatca
    39841 cattttccaa aaaaatctcc aaaaaatttt atactagtta ttatgccttt atcaacattt
    39901 aaattaaact caacatttcc accagaatat tttaattcat ttgaaagagt atattttggt
    39961 gaattaccaa aattccaatc ccaagtttcg tattttgatt tagtaagctt ttctatttgt
    40021 tttatatcat gctcactcaa acaataatta gtattatcag tatttgtttt agaaatataa
    40081 tccattatag catctttaaa ttctaatata tccatttttg aatgtaaatg ttcacttata
    40141 ttggttacac gagattttac agattttatt ccttttcctt caaattttat aggtttaacc
    40201 tttaatgctt ttgagaggtc atttatttca gatgaaaata aaagagtccc atgatgcatt
    40261 actttgtttt tgtagttgta ttgagcattt ccagaaaatt tcttgccatc tataagaagg
    40321 tcatttcttc cagaaaattc ggcattgaca tctagtgttt taagtaaatc tattatgggc
    40381 tgagtgaatc ttctgaaatc actaaaatta ttattgttac aagctataaa tgtaaaattt
    40441 atatttccca aatcatgaaa tacagctcca ccaccagact gtctcctaac gacaggtata
    40501 gaatattctt ttatatattc taaatttatt tcagaaagtg tgttttggtt ttttccaaca
    40561 attatagaag gttcattcct ccataaaata aataagtctt catcaaaatt ttttagaaga
    40621 tattcttcca ttgctaaatt aaaataaggg tttgtttttt cattataaat taataacatt
    40681 aaagtagttc ctccatagaa ttgataaaat ttttattatg aatacaatta attttataat
    40741 tcgacaataa tataaaaact cctttaaatt agaaatttta aaaactacct tgcaaagttt
    40801 aaataaataa tatatactca aaatatgttt aataaaagtg aatagaaggg tagaggcgca
    40861 ataatctatc agtactaata aggagttaag cacagagagt tattaggaaa ggagatattg
    40921 ccgaagtttt ataatcgatg ctttaagatt atattgctgg gggtacatag aaaatatgta
    40981 caactgtcac aggtttattt gtggtgagct atcatttaag gaattatatt atatttattt
    41041 ttactattgt tgatatattg taatgtttaa gccttgagtg tttaccactc aaggcttttt
    41101 tagttttatt gtaacataat accctgtaca gttcacaaaa ttaaaaggag agggagattt
    41161 atatgaggaa caaaaaaatt aatattattt ttctgacgac aatcatgttc ataatgtcaa
    41221 cagtaatggt ttttgcagaa gaagatatag acactattgc actagccaat gcagaaaaat
    41281 ttgggatttt aactttaata ccaccattag ttgctataat acttgcattt ataactaaaa
    41341 acgtaataat ttctttactt ataggtattc tttctggtag ttttataatt aaagctagtg
    41401 gtattaatgt ttttgcgaca tttatacagg catttttaga tttagtagat agagctttag
    41461 tatctttagc agacccttgg aatgcaggga taatactaca ggttttggca attggaggag
    41521 taataaatct tgttgctaaa atgggaggag ctaaagccat agctgaagca cttgctaaaa
    41581 gagcaaagtc agcaaaaggg acacagctta taacatggtt tttggggctt ttagtattct
    41641 ttgatgatta tgccaattca ctaatagtag gtcctatgat gagacctgtt gcagataaaa
    41701 tgaaaatatc gagagaaaag ctggcattta taatagatgc cacagcagca ccagttgctg
    41761 gtttagctat aatatctaca tggataggtc ttgaggttgg tttaatacat gatgcttttg
    41821 aaagtataag tatagatgta gatgcatttg gtatattttt aaatacaata ccatttagat
    41881 tttacaatat attaatatta gctttcattg taatatcagc attattatta aaagaatttg
    41941 gtccaatgag aaaagctgag ataaaatcta gaagtagaaa aattagtata gaccttgatg
    42001 aaggcgtaga agagttggat gatttagctc caaaaaatgg agtaaaattg agtgtatgga
    42061 atgctataat cccaatagga acattgataa tagttgcatt agcatcattt tattatagtg
    42121 gatatacatc tataatggga ggagacgata aggctctgat acaactattt acaaattctc
    42181 catattcttt tgaagcaata aaagaagcat ttagcgcatc tgatgcatct agagcattat
    42241 tccagtctgc acttgttgca agtttagttg ctattataat ggctgtagta aaaaagattt
    42301 ttacaatatc agaagcaatt gatgtttgga tagatggaat gaaaagttta gtaatcactg
    42361 gtgtaatatt aatacttgca tggtcattaa gttcagtaat aaaagagtta ggtacagcta
    42421 aatttttaat acacctatta tcaggttcac taccaccatt cttattacca agtttaatat
    42481 ttggtttagg agcaataata tcttttgcta ctggaacagc ttatggaaca atgggtatac
    42541 ttatgccact tgcaattcca ttagcatact cattaaatcc tgatatgtct tatgtaatag
    42601 taagtactag tgcagtttta acaggtgcaa tatttggaga ccattgttct ccaatttcag
    42661 atacaacaat actttcttca atgggagctg gctgtaatca tatagaccat gttaacactc
    42721 aaatgccata tgctatattt acagcagtaa tcactattgt atttgggtat ataccagctg
    42781 gacttggatt gccaatatat atagtattac cagtggcaat agctgctata tttgtaggta
    42841 ttcaaataat tggtaagaaa gttgatgaag cggaaataga acttgtagaa taaagatata
    42901 aataagtttc accttttatt atcactattt tgttagtttt tagataattt taaaaagtta
    42961 ttgaaaataa tggcgaaata tagtaaaata aaagagtgat aagcggatgt ggcggaattg
    43021 gcagacgcac tagacttagg at
//
LOCUS       DAEPUT010000232        29663 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.guided.047, whole genome shotgun sequence.
ACCESSION   DAEPUT010000232 DAEPUT010000000
VERSION     DAEPUT010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29663
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.guided.047"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            14..238
                     /locus_tag="KRL22_003992"
     CDS             14..238
                     /locus_tag="KRL22_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274367.1"
                     /translation="MSGTYLSIYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFL
                     IIAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            355..852
                     /locus_tag="KRL22_003993"
     CDS             355..852
                     /locus_tag="KRL22_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1274368.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            827..1333
                     /locus_tag="KRL22_003994"
     CDS             827..1333
                     /locus_tag="KRL22_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1274369.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            1317..3764
                     /locus_tag="KRL22_003995"
     CDS             1317..3764
                     /locus_tag="KRL22_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1274370.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            3767..5944
                     /locus_tag="KRL22_003996"
     CDS             3767..5944
                     /locus_tag="KRL22_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1274371.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            5941..6942
                     /locus_tag="KRL22_003997"
     CDS             5941..6942
                     /locus_tag="KRL22_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH1274372.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            6939..7871
                     /locus_tag="KRL22_003998"
     CDS             6939..7871
                     /locus_tag="KRL22_003998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1274373.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            8123..10042
                     /gene="tet(M)"
                     /locus_tag="KRL22_003999"
     CDS             8123..10042
                     /gene="tet(M)"
                     /locus_tag="KRL22_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBH1274374.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            10161..10328
                     /locus_tag="KRL22_004000"
     CDS             10161..10328
                     /locus_tag="KRL22_004000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBH1274375.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(10388..10741)
                     /locus_tag="KRL22_004001"
     CDS             complement(10388..10741)
                     /locus_tag="KRL22_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274376.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            11246..11668
                     /locus_tag="KRL22_004002"
     CDS             11246..11668
                     /locus_tag="KRL22_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1274377.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            11665..11895
                     /locus_tag="KRL22_004003"
     CDS             11665..11895
                     /locus_tag="KRL22_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274378.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            12356..12559
                     /locus_tag="KRL22_004004"
     CDS             12356..12559
                     /locus_tag="KRL22_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1274379.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            12641..13858
                     /locus_tag="KRL22_004005"
     CDS             12641..13858
                     /locus_tag="KRL22_004005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1274380.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            14457..15377
                     /locus_tag="KRL22_004006"
     CDS             14457..15377
                     /locus_tag="KRL22_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1274381.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            15463..17883
                     /locus_tag="KRL22_004007"
     CDS             15463..17883
                     /locus_tag="KRL22_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1274382.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQTNSSESEIGDEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHNILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            17883..18905
                     /locus_tag="KRL22_004008"
     CDS             17883..18905
                     /locus_tag="KRL22_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBH1274383.1"
                     /translation="MNKNNCLDLIFEKVNPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDIFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKNWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            19058..19804
                     /locus_tag="KRL22_004009"
     CDS             19058..19804
                     /locus_tag="KRL22_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1274384.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            19890..21140
                     /gene="cme"
                     /locus_tag="KRL22_004010"
     CDS             19890..21140
                     /gene="cme"
                     /locus_tag="KRL22_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HBH1274385.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(21657..22670)
                     /locus_tag="KRL22_004011"
     CDS             complement(21657..22670)
                     /locus_tag="KRL22_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1274386.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKYSILKGFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(22673..23701)
                     /locus_tag="KRL22_004012"
     CDS             complement(22673..23701)
                     /locus_tag="KRL22_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1274387.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            complement(23701..24546)
                     /locus_tag="KRL22_004013"
     CDS             complement(23701..24546)
                     /locus_tag="KRL22_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1274388.1"
                     /translation="MIKVRELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            complement(24978..26108)
                     /locus_tag="KRL22_004014"
     CDS             complement(24978..26108)
                     /locus_tag="KRL22_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1274389.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            complement(26105..26776)
                     /locus_tag="KRL22_004015"
     CDS             complement(26105..26776)
                     /locus_tag="KRL22_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1274390.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            complement(27001..27650)
                     /locus_tag="KRL22_004016"
                     /pseudo
     CDS             complement(27001..27650)
                     /locus_tag="KRL22_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
     gene            28499..29092
                     /locus_tag="KRL22_004017"
     CDS             28499..29092
                     /locus_tag="KRL22_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1274391.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
BASE COUNT        10252 a         4909 c         4916 g         9586 t
ORIGIN      
        1 tgagatattt ataatatcag gaacttacct atccatatat aactggtttc tatcaaacgc
       61 tcaatcactg gtgcttttag caatcgttgt gattggcttg tatcttggct tcaagcgtga
      121 gtttagcaaa ctgattggct ttttaattat tgcgattatt gcggttggct tagtcttcaa
      181 cgctgctgga gtaaaagaca ttttactaga gctattcaat cgcattattg gtgcttaaat
      241 aaaaccgttc ttttgtggaa tataagtggt tttcttatgt tccgcaaagg aatggtacac
      301 caaacgaagt gcggtaggga tttttgaatc tctacaaaga aaggacgtga atatatggac
      361 gatatgcaag tctatattgc gaatttaggc aaatacaatg agggcgaatt ggtcggtgcg
      421 tggtttacct ttcccattga ctttgaggaa gtcaaagaga aaatcggctt gaatgatgaa
      481 tatgaggaat acgccattca tgactacgag ttacccttta cggttgacga atacacttcc
      541 attggcgaac tcaatcgact atgggaaatg gtatcggaat tacccgaaga attacaatcg
      601 gagctatctg ctctgctcac tcatttttca agcattgaag aactaagcga acatcaagag
      661 gatattatca ttcattccga ttgtgatgat atgtatgacg tggcacgcta ctacattgaa
      721 gaaacgggtg ctttaggcga agtaccagct agtcttcaaa actatattga ttatcaagcc
      781 tatggtcggg atttagacct ttcaggaacg tttatctcaa ccaatcatgg gatttttgaa
      841 atcgtctatt aaatctgtcg gtacattact actggcagat tttctatttt acggggtggc
      901 tcaatcagct acccctattt tttatgaaag gattgattac atgaagaaaa tacgaagcta
      961 taccagtatc tggtctgtgg aaaaggtact gtattctatc aatgatttta gacttccgtt
     1021 tcccataacc tttacgcaaa tgacatggtt tgtcgtgtca ctctttgcag tgatgatact
     1081 tggcaacttg ccccctcttt ccatgataga gggagcattt ctcaaatact ttgggattcc
     1141 tgtggctttc acatggttta tgtctacaaa aacttttgat ggtaaaaagc cttatggatt
     1201 tttgaagtct gtcattgctt atgcactgcg accaaagctg acctatgcag gaaaaaaagt
     1261 aacgcttggc agaaaccagc cacaagaagc cattacagca gttaggagtg aattttatgg
     1321 catatccaat taaatacatt gaaaacaatc tcgtctggaa taaagacggg gaatgttatg
     1381 cttactatga gcttgttcct tacaattact catttctaag tccagaacag aaaatacaag
     1441 tgcatgattc tttcagacag cttatcgcac aaaatcgtga tggcaaaatt catgctttac
     1501 aaatcagtac agaatccagc atacgttctg cacaagagcg ttccaaaaat gaagtcactg
     1561 gcaagctcaa agcggttgcc tatgacaaaa tcgaccaaca gacagacgct ttaatatcca
     1621 tgattggcga aaatcaagtg aactaccgtt tctttatcgg ctttaagttg cttctcaacg
     1681 atcaggagtt ttctatgaaa agtcttaccg ttgaagcaaa aaatgctttg tctgattttg
     1741 tctatgatgt gaaccataag ctgatgggcg attttgttag tatgagtaat gatgaaatcc
     1801 tgcgttttca gaagatggaa aagctcttag aaaataaaat ctctcgtcgt ttcaaaatcc
     1861 gcaggttaga taaggacgac ttcggctatc tgattgaaca cctttacgga cagacaggca
     1921 ctgcctatga agagtatgag taccatctat caaagaaaaa gctggataat gaaacgctga
     1981 ttaaatacta tgacttgatt aagcctactc gctgtttggt ggaagaaaaa cagcgatatt
     2041 tgaaaatcca gcaggaagat gaaaccgtct atgtagctta ctttaccatt aacagcattg
     2101 tcggagaact ggacttcccg tcctctgaaa tcttctacta ccagcaacag caatttacat
     2161 tcccgattga tacgtcaatg aatgtggaaa ttgtagcgaa tcgtaaagcc ctatctactg
     2221 tccgcaataa aaagaaagaa ctgaaagact tggataacca cgcttggcaa agtgataatg
     2281 aaaccagctc caatgtggcg gaagctctgg aaagtgtgaa tgagctggaa accaatttag
     2341 accaaagcaa ggaatctatg tacaagctgt cttatgtggt aagggtatca gcaaatgatc
     2401 ttgacgaact caaacgtcgt tgtaatgaag tgaaagattt ttatgacgat ttaagcgtaa
     2461 aactggtacg accatttggg gatatgctcg gcttacatga agaattttta cctgccagca
     2521 agcgttatat gaatgattat attcaatacg tgacctctga tttcctcgct ggtttaggtt
     2581 ttggtgctac tcaaatgctg ggggaaaatg aggggattta tgttggctac agcttagata
     2641 ctggacgcaa tgtctatctg aaacctgctc ttgccagtca aggggttaag ggttcagtaa
     2701 ccaatgcgtt agcgtcggct tttgttggtt cgctgggtgg tggtaaatcc tttgcgaata
     2761 accttatcgt ctattatgcg gtgctttatg gggcacaagc agtgattgta gacccaaaag
     2821 cagaacgtgg cagatggaaa gaaaccttgc cagagatttc ccatgaaatc aatatcgtca
     2881 ctctgacttc tgatgagaaa aacaaaggct tacttgaccc ttatgtgatt atgaaaaatc
     2941 ccaaagattc tgaatcactg gctattgata ttctgacatt ccttacgggg atttcctctc
     3001 gtgatgggga acgcttccca atccttagaa aagccattcg tgcagtaacc aatagtgaag
     3061 tacgagggtt gatgaaagtg attgaggaat tacgggttga gaatacgcca ctaagtacca
     3121 gtatagccga ccatatcgaa agttttacag actatgactt tgcacattta ttattcagta
     3181 atggttatgt ggagcagtct atcagcttag aaaaacaact gaacattata caggttgcgg
     3241 acttggtact tcccgacaag gaaacttcct ttgaggaata taccactatg gagcttttat
     3301 ccgttgctat gctgattgtc attagtacct ttgctttaga ctttatccat acagaccgaa
     3361 gcattttcaa gattgtagat ttagacgaag catggagctt tttacaggta gcacaaggaa
     3421 aaacactatc tatgaagctg gttcgggctg gtcgtgctat gaacgctggg gtatatttcg
     3481 tgacccaaaa tacagacgac ctcttagatg aaaaactgaa aaataacctc ggcttaaaat
     3541 ttgcatttcg ttccactgac cttaacgaga ttaaaaagac cttagccttt tttggtgtag
     3601 acccagagga cgaaaacaat cagaagcgat tgcgtgattt ggaaaacggg caatgcctta
     3661 tcagtgattt atatggtcgt gtcggtgtga tacagttcca ccctgtattt gaagaactgc
     3721 tccatgcctt tgataccaga ccacctgtgc gaaaagaggt gtaaatgtga aaccatcaat
     3781 agtaaacaga ataaaatcaa actggacgct gaaacgtcta ggtaaagtgg caatgacagt
     3841 ggctttcaca cttgtgattg ccatttttct tttagccatg ctgggaacgg tggttcaagc
     3901 tgcgggcttg gtagatgata cggtcaatgt ggcaaatgaa tacagccgat acccacttga
     3961 aaactatcaa ctggattttt atgtggataa tagctggggc tggcttccgt ggaactggtc
     4021 ggacgggatt ggaaaacagg tcatgtatgg actatatgcc attaccaatt ttatttggac
     4081 aatcagtttg tatgtttcca atgcgacagg ttacttagta caggaagcct attccttaga
     4141 cttcatttcc gctacagcag attccattgg taagaatatg cagaccttag ctggtgtgag
     4201 tgcaaacgga ttttcaacag agggtttcta tgttggattc ctcttactct tgattttggt
     4261 tcttggggtt tatgttgcct atacgggact gataaagaga gaaaccacaa aggcaattca
     4321 tgccattatg aattttgtgc tggtgtttat cctatcggct tcctttattg cctacgctcc
     4381 cgactacatt aaaaaaatca atgacttttc atcagacatc agtaatgcca gtttatcact
     4441 tggcacgaag attgtcatgc cccattccga tagtcaaggc aaggacagcg tggacttaat
     4501 cagagatagc ctgttttcca tacaggttca gcaaccgtgg ctactgcttc aatacaacag
     4561 ttcagacatt gaaagtatcg gtattgaccg tgtggaaagc ctgctctcca ccagcccaga
     4621 ttccaacaat ggcgaagaca gagaaaaaat tgttgcggaa gaaattgaag acagaagcaa
     4681 taccaatcta accattacaa agaccattaa ccgtttaggt acagtcttct tcctatttgt
     4741 cttcaatatt gggatttcca tatttgtatt cctattaaca ggaatcatga ttttctcgca
     4801 ggtacttttt atcatctatg ctatgtttct gcctgtgagc tttattttaa gcatgattcc
     4861 atcatttgat ggtatgtcaa aacgagccat aacaaagctc tttaatacca ttttgacacg
     4921 agctggaatc acattgatta ttacgacagc atttagtatt tcaaccatgc tctatacctt
     4981 atcggctggt tatccgttct ttttgattgc ttttctacag attgtgacct ttgcaggaat
     5041 ctacttcaag ctgggcgatt taatgagtat gttttctcta cagagtaacg attctcaaag
     5101 tgtgggaagt cgtgtgatga gaaaacctcg tatgcttatg cacgctcaca tgcaccgtct
     5161 acagcggaaa cttggacgtt ccatgactac tctaggggct gggtctgcca ttgttacagg
     5221 taaaaaagga cagtcgggtt cggggagttc tgcaaggaca caagcagatc actcccgacc
     5281 agacggaaag gaaaaatcaa cacttggaaa acgtatcggt caaaccatcg gtacagtagc
     5341 tgataccaaa gacagaatgg tagacactgc tagtggtttg aaagaacagg ttaaagattt
     5401 gccgaccaat gcaagatatg cagtatatca aggaaaatcc aaagtaaaag agaatgtccg
     5461 tgatttaacc agtagtattt ctcaaaccaa agcggacaga gccagtggac gcaaggaaca
     5521 gcaggaacaa aggcgaaaaa ccattgcgaa gcgtcgctct gaaatggaac aggtcaaaca
     5581 gaaaaaacag cctgcttctt ctgttcatga aagaccgact acaagacaag aacaatatca
     5641 tgatgaacag acctcaaaac agtctaatat tcagacttca tataaggaat ctcaacaagc
     5701 caaacaagag cgtccagcag ttaagtccga tttttcaagt ccaaaagtgg aacgccaagg
     5761 caataccgtt caagaaaaaa ccgttcaaaa gccagcaact tcaaccacta cagcagatag
     5821 aacttcacaa cgtccaatca caaaagaacg tccgtctact gttcaaagag taccactaca
     5881 aaatacaaga agtagaccac caatcaaaac cgccaccatt aagaaagtcg gtaagaaacc
     5941 atgaagttga aaactttagt gattggtggt tctggattat tcttgatggt cttctcactg
     6001 cttctgtttg ttgccatttt attttcagat gaacaggaca gcggaatttc caatattcat
     6061 tatggaggtg tgaatgtttc cgcagaagtg ctggctcata agcctatggt agaaaaatat
     6121 gccaaagaat atggcgttga agaatatgtc aacatacttc ttgcgattat acaggtggaa
     6181 tcgggcggta ctgcggaaga tgttatgcag tcctcggaat ccctcggtct tccacctaat
     6241 tcattgagta cagaagaatc cattaagcaa ggtgtgaagt atttcagtga attattagcc
     6301 agtagcgaaa ggctcagtgt agatttagaa tcggttatcc agtcctacaa ttatggtggt
     6361 ggtttcttag ggtatgtggc taatcgtgga aataaatata cctttgaact ggctcaaagt
     6421 ttctcaaaag agtattcagg tggcgaaaaa gtgtcttacc ccaatcccat agccatacct
     6481 atcaatgggg gctggcgata caactatggc aatatgtttt atgtgcaact ggtaacgcag
     6541 tatcttgtca caacagagtt tgatgatgat acggtacaag ccatcatgga cgaagcactg
     6601 aaatatgagg gctggcgata cgtttacggt ggagcttccc cgactacttc ttttgattgt
     6661 agcggactga cacaatggac gtatggaaaa gctggaatta acttaccacg aaccgcacaa
     6721 cagcaatatg atgtgaccca gcatatccca ctatcggaag cacaagctgg cgatttggtt
     6781 ttctttcatt ctacctataa cgctggctct tatattactc atgttgggat ataccttggc
     6841 aataaccgta tgtttcatgc aggcgaccca atcggttatg ccgacttaac aagcccctac
     6901 tggcaacagc atttagtggg agcaggacga atcaaacaat gagaaaggaa gatttaatga
     6961 tgaaatttag aaaaaatcag aataaagaaa aacagatacc aaaggaaaag aaacctcgtg
     7021 tctataaggt caatcctcat aaaaaggttg tgattgcctt gtgggtactt ttagggctta
     7081 gtttcagctt tgcgatattc aagcacttta cagctataga tactcatact attcacgaaa
     7141 caactatcat agaaaaggaa tacgttgata ctcatcatgt agaaaatttt gtagagaact
     7201 ttgcgaaagt ctactattca tgggagcaat ccgataagtc cattgataat cgaatggaaa
     7261 gtctaaaagg ctatctgaca gatgaacttc aagctctcaa tgttgataca gtacgcaaag
     7321 atattcctgt atcgtcttct gtaagaggat ttcagatatg gacggtagag ccaactggcg
     7381 acaatgagtt taatgtaacc tacagtgtag accagctcat tacagaggga gaaaatacaa
     7441 agaccgtcca ctctgcttat atagtgagtg tctatgtaga tggttctgga aatatggtac
     7501 tggttaagaa tccgaccatt accaacatac ctaagaaatc aagttataaa ccaaaagcca
     7561 ttgaaagtga ggggacggtt gattccatta caaccaatga aatcaatgag tttttaacga
     7621 cgttcttcaa gctctatcct acagcgacag ccagtgaact ttcctactat gtgaatgacg
     7681 ggatattaaa accaatcgga aaagagtaca tctttcaaga actggtaaat cctattcaca
     7741 atcgtaagga taatcaagtc acggtatcgc tgacagtgga gtatatcgac cagcagacca
     7801 aagcaacgca ggtatctcaa tttgatttgg tacttgaaaa gaacgggagt aattggaaga
     7861 ttgtaaaata acaaatattg gtacatgatt acagatactt tgtaatcatg tactcttttt
     7921 gataaaaaat tggagattcc tttacaaata tgctcttacg tgctattatt taagtgacta
     7981 tttaaaagga gttaataaat atgcggcaag gtattcttaa ataaactgtc aatttgatag
     8041 cgggaacaaa taattagatg tcctttttta ggagggctta gttttttatg cccttttggg
     8101 tttttgaatg gaggaaaatc acatgaaaat tattaatatt ggagttttag ctcatgttga
     8161 tgcaggaaaa actaccttaa cagaaagctt attatataac agtggagcga ttacagaatt
     8221 aggaagcgtg gacaaaggta caacgaggac ggataatacg cttttagaac gtcagagagg
     8281 aattacaatt cagacaggaa taacctcttt tcagtgggaa aatacgaagg tgaacatcat
     8341 agacacgcca ggacatatgg atttcttagc agaagtatat cgttcattat cagttttaga
     8401 tggggcaatt ctactgattt ctgcaaaaga tggcgtacaa gcacaaactc gtatattatt
     8461 tcatgcactt aggaaaatgg ggattcccac aatctttttt atcaataaga ttgaccaaaa
     8521 tggaattgat ttatcaacgg tttatcagga tattaaagag aaactttctg ccgaaattgt
     8581 aatcaaacag aaggtagaac tgtatcctaa tatgtgtgtg acgaacttta ccgaatctga
     8641 acaatgggat acggtaatag agggaaacga tgacctttta gagaaatata tgtccggtaa
     8701 atcattagaa gcattggaac tcgaacaaga ggaaagcata agatttcaga attgttctct
     8761 gttccctctt tatcatggaa gtgcaaaaag taatataggg attgataacc ttatagaagt
     8821 tattactaat aaattttatt catcaacaca tcgaggtccg tctgaacttt gcggaaatgt
     8881 tttcaaaatt gaatatacaa aaaaaagaca acgtcttgca tatatacgcc tttatagtgg
     8941 agtactacat ttacgagatt cggttagagt atcagaaaaa gaaaaaataa aagttacaga
     9001 aatgtatact tcaataaatg gtgaattatg taagattgat agagcttatt ctggagaaat
     9061 tgttattttg caaaatgagt ttttgaagtt aaatagtgtt cttggagata caaaactatt
     9121 gccacagaga aaaaagattg aaaatccgca ccctctacta caaacaactg ttgaaccgag
     9181 taaacctgaa cagagagaaa tgttgcttga tgcccttttg gaaatctcag atagtgatcc
     9241 gcttctacga tattacgtgg attctacgac acatgaaatt atactttctt tcttagggaa
     9301 agtacaaatg gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg agatagaact
     9361 aaaagagcct acagtcattt atatggagag accgttaaaa aatgcagaat ataccattca
     9421 catcgaagtg ccgccaaatc ctttctgggc ttccattggt ttatctgtat caccgcttcc
     9481 gttgggaagt ggaatgcagt atgagagctc ggtttctctt ggatacttaa atcaatcatt
     9541 tcaaaatgca gttatggaag ggatacgcta tggctgtgaa caaggattgt atggttggaa
     9601 tgtgacggac tgtaaaatct gttttaagta tggcttatac tatagccctg ttagtacccc
     9661 agcagatttt cggatgcttg ctcctattgt attggaacaa gtcttaaaaa aagctggaac
     9721 agaattgtta gagccatatc ttagttttaa aatttatgcg ccacaggaat atctttcacg
     9781 agcatacaac gatgctccta aatattgtgc gaacatcgta gacactcaat tgaaaaataa
     9841 tgaggtcatt cttagtggag aaatccctgc tcggtgtatt caagaatatc gtagtgattt
     9901 aactttcttt acaaatggac gtagtgtttg tttaacagag ttaaaagggt accatgttac
     9961 taccggtgaa cctgtttgcc agccccgtcg tccaaatagt cggatagata aagtacgata
    10021 tatgttcaat aaaataactt agtgtatttt atgttgttat ataaatatgg tttcttgtta
    10081 aataagatga aatatttttt aataaagatt tgaattaaag tgtaaaggag gagatagtta
    10141 ttataaacta caagtggata ttgtgtcctg tatgtggaaa taaaacacga ttaaagataa
    10201 gggaagatac tgaattaaaa aaattccccc tctattgtcc gaaatgcaga caagaaaatt
    10261 taattgaaat aaagcagttc aaagtaactg tgattacaga gccagacgca aagacgcaga
    10321 gccgataaaa tgagattaat acaatctcat tttatcggct ctttccgtta tgtatggatt
    10381 cttttaatta gtcttcgatg tttcttgctt cgttgatacc gctggctaaa gattccatta
    10441 aggatagttc tttgtctgta aagctatcca tgtatttctc tatctgtaat cgtcgggtgc
    10501 tttttaccaa gttattagca ggtaagaaaa attcatcaac ggaaacatga agtaacgata
    10561 caaggtcata aagaacttgt atgctggggt gttgcccttt attttcaata ttagttaagt
    10621 accgtgggtc aatttcaatc aatgctccca cttgttcacg agttaaacct cgtttcaatc
    10681 gagcttcttt aatggctaaa ccaaaggctc taaaatcata tttatcttct tttttacgca
    10741 tagtagacca cctctataca ttttattgtt cctactgaat taaaaacagg tatagaaaaa
    10801 cgtgttatat ggtttatagg tttatattta ataaaaagca ctactaaacg ccaataaaaa
    10861 aaaccgttat atggtagtgc tatttacgct gttaaaatat tgtatattac ttccaaatgg
    10921 cggtttgttg gaggtcaacg tcgccatgaa gtacatcata tacaataaat ttccttacat
    10981 tgggttcttg tcaaaaaaag tcgtctatct gcaatagata agtacgtcca ccaatgtggt
    11041 tttataaatc atatagatag aataacagaa gcatgtaaac agagaaataa atctgtttat
    11101 atgctttttt ggctattcag aactttttta caaagtttat ttatcagtaa tgcaacaaat
    11161 ccccctttca cattgggact aagagtgaaa ggagataaac gagcaaggct cacttccttt
    11221 cctagacaga aagggggtga gaaacatgaa accatcttct tttcagacca caatagaaaa
    11281 tcagtttgac tatatctgta aacgtgctat ggaagacgag cgaaagaatt atatgcttta
    11341 tctttcaagg attgcaaagc gtgaggtgtc cttttcggat gttggcgatt atcttgttag
    11401 ccagtttgcg acaacagata actattcaac tgactttcag atttttacac tcaatgggtt
    11461 atcagtaggc gttgaaaatg atttgttgag tgaagcatta cgtgagttgc cagacaagaa
    11521 acgtgaaatt ctactgctgt tttactttat ggacatgagc gattcagaaa ttgcagacct
    11581 gttgaaattg aaccgttcta ctgtctatcg gcatagaacc agtggactag ccttaattaa
    11641 aaagtttatg gaggaatttg aagaatgaaa acacaatatc ctatgattcc ctttcctctc
    11701 attgtaaagg caacagatgg cgataccgaa gcgattaacc agattctaca tcattacaga
    11761 gggtacataa cgaagcgttc cctacgactt atgaaagatg aatatggcaa tcaaagtatg
    11821 gtcgttgatg aagtcttacg tggaagaatg gaaaccagac tgattacaaa gattttgtca
    11881 tttgaaatta agtaatatcc tctctccttt cgtggaagcg tgctaaacca ttccacgctt
    11941 cccgaacagg gaggtttgtt attccaccaa agcatattga gctttcaatg tgttttgata
    12001 ggctaacgag ccattgttct ttgaaaactg aataaaagta atcgaatacg tttcgataag
    12061 aaaagagcca acggaactaa ccgccatgac ctatcttata aagatagcga gcgattcatg
    12121 ttagtgatcc gagaagcaat ctttagcagg attgcctgca acgacattct tatcgtgata
    12181 atgatactcc catacagtca atagtccgag cgtgataaaa ccgtcgcagg caatgagtat
    12241 ggctacatga gaaccatgca ggggtggaac tcccgtgagc tttgctaaag ctgttcgatt
    12301 gctggtaaaa caacttttat gaaatccaaa taagtgattt ggaaaggagg attttatgaa
    12361 gcagactgac attcctattt gggaacgtta taccctaacc attgaagaag cgtcaaaata
    12421 ttttcgtatt ggcgaaaaca agctacgacg cttggcagag gaaaataaaa atgcaaattg
    12481 gctgattatg aatggcaatc gtattcagat taaacgaaaa caatttgaaa aaattataga
    12541 tacattggac gcaatctagc gtcgccaaag ggtcttgtat atgataaaat agtattaagt
    12601 cgtatcaagg ctctttccat aaaggaaagg agcaaatgcc atgtcagaaa aaagacgtga
    12661 caataaaggt cgaatcttaa agactggaga gagccaacga aaagacggaa gatacttata
    12721 caaatatata gattcatttg gagaaccgca atttgtttac tcgtggaaac ttgtggctac
    12781 agaccgagta ccagcaggaa agcgtgattg tatctcactt agagagaaaa tcgcagagtt
    12841 acagaaagac attcatgatg gtattgatgt tgtaggaaag aaaatgacac tctgccagct
    12901 ttacgcaaaa cagaacgctc aaagaccaaa ggttagaaaa aacactgaaa ctggacgcaa
    12961 atatcttatg gatattttga agaaagacaa gttaggtgta agaagtattg acagtattaa
    13021 gccatcagac gctaaagaat gggctattag aatgagtgaa aatggttatg cttatcaaac
    13081 catcaataac tacaaacgtt ctttaaaggc ttcattctat attgctatac aagatgattg
    13141 tgttcggaag aatccatttg actttcaact gaaagcagtt cttgatgatg atactgtccc
    13201 taagaccgta ctaacagaag aacaggaaga aaaactgtta gcctttgcaa aagctgataa
    13261 aacctacagc aaaaattatg atgaaattct gatactctta aaaacaggtc ttcgtatttc
    13321 agagtttggt ggtttgacac ttccagattt agattttgag aatcgtcttg tcaatataga
    13381 ccatcagcta ttgagagata ctgaaattgg gtactacatt gaaacaccaa agaccaaaag
    13441 tggcgaacgt caagttccta tggttgaaga agcctatcaa gcatttaagc gagtgttagc
    13501 gaatcgaaag aatgataagc gtgttgagat tgatggatat agtgatttcc tctttcttaa
    13561 tagaaagaac tatccaaaag tggcaagtga ttacaacggc atgatgaaag gtcttgttaa
    13621 gaaatacaat aagtataacg aggataaatt gccacacatc actccacata gtttgcgaca
    13681 tacattctgt accaactatg caaatgcagg aatgaatcca aaggcattac agtacattat
    13741 gggacatgct aatatagcca tgacgctgaa ctattacgca catgcaacat tcgattctgc
    13801 aatggcagaa atgaaacgct tgaataaaga gaagcaacag gagcgtcttg ttgcttagta
    13861 gtacaaatga atttactact tatttaccac ttctgacagc taagacatga ggaaatatgc
    13921 aaagaaacgt gaagtatctt cctacagtaa aaatactcga aagcacatag aataaggctt
    13981 tacgagcatt taagaaaata taaaaagata attagaaatt tatactttgt ttaatataaa
    14041 aattttatta aatttagtat gtaatttttt aatcttattt tattccatct atagtcttat
    14101 gctaaataat aactttgata atatttccct aacttatgtt tcaactggtt tatattgcaa
    14161 tttatttaat tacagcttat ttgcataata attcgtccat atcataagtt gtgtatttat
    14221 ataaatacac aattaaaaat aaatcactat ggtatactaa ttattacgaa gactatactt
    14281 atatgcaaag ataaatataa ggcatcttat atcttttatt aattataaat atcttttatc
    14341 aattataaaa aattaaacgc tatcttattt atcataaatt acaaaaacat aaaattttat
    14401 tactatattg ctataaatta attgatacac attttacaca ataaggaggg ctatatatga
    14461 caaatgctaa aagtaaaaaa gaatatctaa atcgtatttg caaagtgcaa gactatatag
    14521 aagaacattt acatgaacct ctttctcttg atgaactttc taatatagca ggtttttcaa
    14581 aatttcactt tcatagaatc ttcaaagcaa tagaaaaaga aactttggca caatatgtaa
    14641 ataggctaaa actagaaaat gcaactgctt ttcttattca tagaactgac atgactgtta
    14701 ctgatattgc acactacttt ggctttactg attcagcagt tttctcgaga gcatttaaaa
    14761 attactataa aataagccct ataaaatata gaaacaatta tagcaagaat tgcaaagaac
    14821 catataaaat ttctcagtac aatagaagca tatcaaaacc taaatgtaag aatactagag
    14881 aggttaaagg tgaaattgaa attctagaac ttgataatat gaatactatt tacactagat
    14941 atactggttc atatggtaat ctaaccagta ctttcccaaa acttttagaa cggttattca
    15001 catatgcaag tgagcagaat ctacttggac ttgaaaacac acaaatatta gccatttatc
    15061 atgataatcc acaatttaca caggagcatc aattaaggac tagtatttgc atgaccattc
    15121 cagataacat agttgtcaaa gagaatgaca atcttggcaa tatgataata ccttctggaa
    15181 aatatcttgt gggacatttt gatatttcaa aatctgaata tagtgatgcg tgggatttta
    15241 tgtataatga atggctatca aatggtaatt ataagctacg tgcctccttc ccttttgaag
    15301 tatatcttaa caacccacac aatcaccctc aaaatagaca cttggtcgat atatatttac
    15361 ctatagaacc tttttaataa cctcacctaa tctattcttg tattaaggat taatatatcc
    15421 ctattttacg gtttgataaa attgataaaa tgaggtgaac caatgaaaga aataaaaatt
    15481 aatggagcaa agatacacaa tcttaaaaat atagatgttt ctatccccaa agataagctt
    15541 gttgttgcaa caggtgtcag tggctcaggt aagtctagcc ttatgtttga cattgtattt
    15601 gaggaagggc gtaaacaata tctgcaatct ttaggtatac ttgcaggtat tgatagtgag
    15661 gataagtttg ataatattca aggtttagct cccactatag ctgttcaaca aaatattatt
    15721 cgccagagca atcctcgttc aacagtaggc acaagaacca atattctcaa catgcttaca
    15781 ctattgtatt cagtggaagg tcaaataatg tgtactatgt gtgatactcc tgtaagcgat
    15841 aatctaattt gcaataattg tggatatgag gaagaacgat taagaccaag ttatttctca
    15901 tacaactctt cagatggaat gtgtatgaag tgctctggac atggtgcata ttttgagatt
    15961 aatattgaaa aattagtcct tgataagcat gacaccctaa aacaagtctt agatagagca
    16021 aagattacac caggatattt gagagtattt tctaaaaaat tcaacgatta tttagacata
    16081 caattcttac aactacctga agaaataaga aatgaagtac tctatggtca ttatgaaaat
    16141 ggtaaaaaaa gttcctcttt atcaaaggta tttcacaatc gttacaaaag gggcgaagat
    16201 ttaaatggag tttatactat gactgcctgt tcagattgca atggttttaa aattggtgaa
    16261 gaagcacgta gagtactttt aaacggaaaa catattggag aacttggaaa aatgacgatt
    16321 ttagaaattg atgatttcct taaactctta ataaatcaag gtaatttaaa cacatttggt
    16381 acaaatcttg taaatgatat tttatccaaa actcaacatt taatagaatc acgattaggt
    16441 catctatcct tataccgaga aatgtcaact ttgagtggtg gggaaatgca aagactattt
    16501 ttaaattcac atctcgattc agagatggac tcattaattt atgtgcttga tgaaccaaca
    16561 gctggattgc atgaatcaga aaaaatagac atcttaaaat caataaagaa acttaaagat
    16621 ttaggaaata cggtcatagt agttgagcat gataaaaaca caattaaaat ggcagaacat
    16681 attattgata ttggtccaaa agctggtgtt gaaggtggtc aattagtata tcaaggagat
    16741 ttagaaggtc tacttcaatc cgacaaatca cttactgggc agtatttatc tggaaaatat
    16801 ccaatgccta atagaacaag caataaaaac attacacata ctgataaaat accttgtata
    16861 actattcaaa atgcaaatac aaataatctt aaaaatgtaa ctgtatcatt acctttgggt
    16921 gctatggttg gaatatctgg aaaatcaggt agtggcaaga gttcacttat atcagacacc
    16981 ctacttcctc ttcttagaag ccaatttaat aaccatacta tcaataatca aacaaattct
    17041 tcagagagcg aaataggtga tgaagacgat tatgcagttg ttgaaactat tgcagataga
    17101 ctgattggta ctaaacatat ttctggatat tcagagatat cccaatctcc tattggcaaa
    17161 aatatgaact caactcctgc ttcttatatt ggtatatggg ataagatacg tacactattt
    17221 gcaggtcagc cagaatcgtt agaacgagga tttacagctg gtcatttctc atttaactcc
    17281 aaaggtgctt gtcctaaatg tagtggtagt ggatatgaaa aggtctggtt gggaaataat
    17341 ctaagtatag accatatatg cagtgaatgt cagggaaaaa gatttaatga tgaatcttta
    17401 tctattaaat ataaaaataa aaatatacat aatattttaa atatgagtgt ttctgaatct
    17461 gtacatttct tcaaggatat tccaaatatt gtttcacact taaatgtatt agaacaaata
    17521 ggtatggggt atataaaatt aggccaacct acaccaactt taagtggtgg tgaatcccaa
    17581 agaatcaaac ttgcaaaaga aattggtaaa aaacgaaatg gtaatatcct ttatgtattg
    17641 gatgagccaa ctaccggtct aagtctatac gatacttcta agttgattca attattagat
    17701 gaattggttg aaaatggaaa ttctgtaatt gttgttgaac atgatataga tgtattaaat
    17761 gtttgtgact ggattgttga gcttggtcca gaaggtggtg acaaaggagg ttatataatt
    17821 gcagaaggtt ctccaaaaac tctaaaagaa aatccaaaat ctataacagg gaggtatctt
    17881 taatgaataa aaacaattgc ttagatttaa tatttgaaaa agtaaatcct tcaagtgttg
    17941 gtatgagttc agaaaagctc tcacaacttg aacctttaat aatctcacaa tatagtaata
    18001 taaatggaat aattattgca agaaaaggaa aagttgtctt tgaaaagtac tataatggat
    18061 ataatgctga tgatattttt catgttgcat cagttacaaa aagtattata tcagccttaa
    18121 taggtattgc aatagataaa ggatatataa aagatgttga ccaaaaggtt gttgattttt
    18181 tccctgaata tacttgtagt ccttctgaaa tatgtaaaaa agcagtaact atacgtcacc
    18241 tacttacaat gactgcacca taccctttta aaaatatgac tgagtcttta gaaagacttt
    18301 gcaaacaaaa aaattggata aaatatacct tgaatcaact tggtcaaaaa ggcgaaattg
    18361 gtactttcaa atattcttca gctggaacgc acctactttc agctattata acaaaaacta
    18421 ctggaaaatc tgctcgtgaa tttgctaatg aatacttatt taaacctatt ggtatgaaag
    18481 ttataccaga ttatgatatg aaagattttg gttttgaaga tttctttgga aaaaatctta
    18541 agggttgggc aaaagataga cagggttatt ctataggtgg ctggggactt acattgagtg
    18601 ctagagatat gttgcgattt ggttttctgt atttaaatga tggtatttgg aataataaac
    18661 gtattatatc taaatcgtgg attgaagaat cggttaaaat gaatagtaat gaatacggtt
    18721 atctgtggtg gctatgtaaa aaagatggtg ttttgtggta ttcagcaatg ggaactggag
    18781 gaaatgctat ttgttgtatt ccacaatatg acttagtaat agccatacca tctaaaatag
    18841 tgtttaaacc tcgtgataga tgggagttta ttgaaaaata tatacttact tctataatag
    18901 attaattact ctttcataga ttaattactc tttcataaat taattactct ttcataaact
    18961 aattactctt agataaccaa accctccatt ataacaccag acttttgttt ggtgttatta
    19021 tgactaatac tatatatcta aaaggagttg aatactaatg gacacttaca cgacatcaga
    19081 ggtagcagat ttaattggtg tacatcctaa tacagtacgt ttatatgaag aactaaactt
    19141 aatacctaaa cctaagcgta ataccaatgg ttatcgtatc tttaatgatt ttcatataga
    19201 acaatttaga tttgctcgta cagccttgaa aattgaagtg gtacaaaggg gattaagaaa
    19261 agatgccctt gagattgtaa gaacatcagc gaatagggac tttgataagg ctattagtct
    19321 tgtaaatcaa tacttgcaac aattagaaat agaaaaatct aatgccgagg aagcacttac
    19381 tattgttgca cagattttaa atggaaatac tccagaaaca aataaactct ttttaactag
    19441 aaaagaaact gcagaacact taaacgttac aatagatact ttaagaaatt gggaaatgaa
    19501 tggtttgtta aaagtaaaaa gaaaacaaaa tggttatcgt gtatatactg atgaagatat
    19561 aaaacgactt aaaattataa gcgcacttcg ttgtgcaaac tattctcttt cagctatttt
    19621 acgaatgtta aatgctttat cttctaatcc taatactaat attaaaactg tccttgacac
    19681 tccaaaagat gatgacgaaa ttatctcagt gtgtgacaaa ctgataactt cattgaaaga
    19741 agctgaacat aatgcaaaaa ccatgaaatc tcatcttcaa attatgaaaa aacaattttc
    19801 ctagccctcc actctaactc cagactttga tttgtgtgtt atccttaaga gcaagaaaaa
    19861 ttcaacacac aaatcaaagg aggaatagga tggaaaataa aaatactaat tctacatgga
    19921 agaaaaaagt cattcttttt ttagcaagtc aatatatttc cttatttggc tcatcacttg
    19981 tacaaatggc aatgatatgg tatgtcacac ttcagacatc atcaggtgta tgggtaacag
    20041 ttttaactgt atgctccttt atacctcaaa tgataatttc tttttttgct ggtgtatggg
    20101 cagactacta caatcgaaag gtactcataa ttgtatcaga ttcaacaatt gctatatcta
    20161 cattagttct aattctattt atgatgtcat caaatggcac aacaagtgaa ttaatagcca
    20221 tatcagtaat atctgttata cgttcactag gaagtggtgt acaaacacct gctgtaaacg
    20281 caatgattcc tcaacttgta ccagaagaac atttaatgcg ttttaatggt ataaatagta
    20341 gtctacagtc tatagtacaa tttatagttc ctattgtagc tgctgcaata cttggatttg
    20401 gtaataaaat aaatcaagtt cttttaattg atgtatttac tgcaattatt gctattgtat
    20461 tattaatatt catcaaaatt cctaaacatg atataccaaa acaaactgaa aaagtctcat
    20521 tttttgcaga tatggtatca gggataaagt actgtttttc agataagttc attagaaaag
    20581 tgctttttac ttatggagca ttcatgcttc tttgtgttcc atcaggattt cttataggac
    20641 ttcttattga acgaacattt ggcaagggtt atatatacct gtctattatt gaaatgattg
    20701 gatttttagg tatggtttta ggtggattga ttataggagt ttttggtggt tttaaaaata
    20761 gaaataagac cttttttcta gcaatattat cctatgctat tttttcaatt attctaggtc
    20821 ttgtaacaca agcttggcaa ttttttatat ttatgttttt tacgaatttt tcaattccaa
    20881 tcattcaagc atcagctatg actatgttgc aagagcatgt agcaccacaa atgctaggta
    20941 gagttcttag cttacctatt attatatata ctggttttat tcctcttggt atgatgattt
    21001 tcggaccaat ggcagatgta atttctatta ataatttaat aatcatagca gggattatac
    21061 ttttattttt tgctttggct atcccctatt caaaacaatt ttacaagcaa ggaatatcta
    21121 agtcaaatga atccgagtaa tatatttaaa tagtttaact cgatttatct ggttaaaaat
    21181 gaaggggctt aaaatggact ttttaattta tgaagaaaat tttttatatg aaatcaaata
    21241 tattttatca tttcaacatt gaaaaatagg tttatcttta ttttgagtcc ctctctttat
    21301 agcaaataat attttgatac tatctttatt aactttatat aataatacct ttacttgtag
    21361 gttataatga tgaaatttat caaatcatat aataatacct ccatttatat cataaattaa
    21421 atttatagta caaatggagg aaaataaagt atttatatag tttaagtacc tattaagttt
    21481 tccactaagt agctctaatt gtactgaact tcttactaaa ttatattgaa taattataaa
    21541 ataaaactaa ctattacact acataaatta aagtatacaa attgcactac ataaattaca
    21601 ctatacaaag tatattaaat cacctattaa attgtcccaa ttataattat actgagttat
    21661 ctactaaaag ataactttct ttttttatct aaaataatat atatcataaa ccatactaca
    21721 caatgtacag ccaaaattac aatatctttg ataataatga cattaccatt aataatctcc
    21781 ataataccat taaatgtagc aactgaaggc attatatagc ataaattccc tataccactg
    21841 gtattaaccc ctagaagata tattaacaaa ggagtaccta taaataaaat cattactatt
    21901 ttaatataaa caattcctac cataagacct tctgacaact ttccaataaa taaacctata
    21961 agtgatgaaa taaatgctga aaatacaacg agtaacaaca tcattatcat atctaatatt
    22021 gaaatatcca aacatataaa tacagttatc attgaagata aacacccaca taaaagaccc
    22081 aaaaatactt tttgtataat atactgactt ctactctgtg gcaaaacttc atttataaat
    22141 gatattccat cttctttttc cgatataata ttcattgcat taaaggtgca tcccataaac
    22201 atagcagtaa ttaaaatcat agcaataaaa acattttgaa acccttttaa aatactatat
    22261 ttaggcaata ttgtaacctc aacatctttt aaatcaccct ttagtctaaa catctctggc
    22321 aatgtctttc caacattttt tatagcatta atctcatttc cataaagcac agtttttatc
    22381 cctttaccat ctctaacaac tccaattgtg tccgttttaa tatccttaat ttcacgtatt
    22441 aaatgcattt ttgtgtcata tacacttacc ataccatact tcttcaacca ctgctctgtt
    22501 tgtacaggaa gtgtatcctt cactatacca aaacgtatct ctcctaatga agatatatca
    22561 attgttccca taaaatttat taaaatcgcc ataacaactg gtaaaaagaa ggaaattata
    22621 cacattttat ctttttttat actctttaac tggtaacgta atcctatcaa gattatccct
    22681 ccctaaccaa ctctttatta aaaatatatt ttacaagtaa aaatagaact attattgtca
    22741 aagaacacac tacaaaataa actaattctt ttgaaaaatt catgaaaaac gcatttttaa
    22801 gctgactata aacatgatag aagggatgat atttaatcca atctatttca aaagatgtat
    22861 ttgcagatag aaatataggt gtagttatga atacagcaac cacaagatat ataagagaaa
    22921 attgcttaaa atctctcaat aacattgagc atcctattcc aatcaaagac ataataattg
    22981 ataaaatact agcttgaact aatacttgtg gaagtatttt tattccttct aaaaatccaa
    23041 tattaaatac tactaaaaga actgtaaaac ataggtcaca tataaaaaaa gcaaatatct
    23101 ttgataatat aaaaagactt ctttttacag gtaaaatacc agtaatacgc attactccca
    23161 tctgcttttc tttaaataat aaagaggcaa tccctaaaaa tccaatagct acaatttcaa
    23221 agaataaaat ctcacaagtc atgtcttttc tttgttttat ctcagatgta tccttatcat
    23281 taatttgaat tattgcattg ttgtctgata ttttgctatt atggtctttt tctgatgata
    23341 ataatgacaa tgcatagtca gctctataat tgtcaactcc tttaatactt tcatgtaaaa
    23401 ttactttcgg cttactggaa ctcatatcaa tacaaactgc acttgtatct tcatcaagtt
    23461 ttgcttttaa ttcacctata gaagaaactt gattaattaa tggagatgca ctcatgctta
    23521 tattctctgg attatataga tatacattat tgtgataact atcttcatcc ataaacttta
    23581 cataaccaaa attaatataa cacgaataaa gtatgagaga gccaagtgtc agcacaaaaa
    23641 atttaccata aatcatcatc caaaaatctt tttttactaa ggtaaaaaat ttagaataca
    23701 ttacactaac atccttcctg tgtatttaat aaaaacttct tctagtgtag gttcttttga
    23761 atgtacactt aagatttcat catatttaaa agttattcca gattctaact cttgtatatc
    23821 tacaatttca atatctcgat ttccattata tacaaattcc acttcaactt tattattgct
    23881 atttttcatt tttaaatttt tgggtttatc tattaccata atctttccat ctgcaataaa
    23941 agccacattg ttacacatta aatctgcatc tagcatatta tgagtagtca aaaagatagt
    24001 tgttcctttt tttcgttctt cttcaataat cttacgaaat agtacagctc cagatgggtc
    24061 aagtccacta gtaggctcat ctaaaaataa caactttgga ttacttacca atgctcttgc
    24121 catgctaata cgttgcttca taccttttga gtaggatgat acaggcttat ttataaactc
    24181 tttcttaaac tctaacaaat ctaagagttc atatatgtct ctcctttgat ttttaggata
    24241 aaaagacgaa aaatattcta aattatcaat tgcacttaaa ttggtatata aataaggaaa
    24301 ttcaaataaa acaccaatct tttgatatag agactctgta tatgctttaa cttccttccc
    24361 aaaaatggat acgtgcccat tgtagccttt taaaacgcca tttaagattt tctgtgttgt
    24421 ggattttcct gaaccattag gtccaaggaa tccaaagatt tctccttctt ttacttcaaa
    24481 attaagtcca tgcaatatct gtttatcttt tccataagaa aattttaact ctcttacttt
    24541 tatcatctat cataacctcc tttatcattt ttttgtcgtc tatcccacca ttttataaat
    24601 ttaattttaa gcagaataga aagcaatatt atcaatataa tagtcaacca tgtataccat
    24661 ttcataagta ctcccccttg taaccttatt taattacgct tctatttttt aatttattta
    24721 acctatttta tttctatttg gtgaaatcag agtgtctctc ttgtgaaatc gaagtgaaat
    24781 aataaaaagc ttaataaaaa atcttgtttt catcaggaaa acaagacttt ttattaagct
    24841 ttttattaaa ctttttatta gactttttca ttaagctttt ttcattaagt ttttttattt
    24901 tattctcttt aaatgcttac atatacaaat aaaaatattt tacatcagat acttatgatt
    24961 tataaattaa tactaaatta ttcatcaatt ggaatcataa aataaaactc tactcctcta
    25021 tcacgattat tcactccata ttctaaccct tgcattgtaa gtatttgtga aacaattgca
    25081 agccctagac ctgaacctcc tgtacgctga gattgaacac tacgataaaa cttagaccaa
    25141 atctttgaaa tctcatcttg ctctataaac ctaccatcat tataaatttc aaataaaagc
    25201 aagccatttt cacatgtaat cgataaatct aaattaccat tatatacaac atgcttcttt
    25261 gcattaataa ctagattctc tactacttgt tccattctca ttttatctgc cactacaaaa
    25321 acttcatact ctggcaaatc atatgtaaaa taaaaattgg catctggtat atcaattaaa
    25381 agacgacctg ccacagtttc aacaaactct ataaaatcaa aacgctctgg gttaagttta
    25441 gaaactcctg cttccaatgc agataagtct aataatgata caatcatatt gttcattcta
    25501 tcagtttctt ctattataac attcatataa tttttctttt tttcttcatc aacttcatcc
    25561 ataagcccct ctgtatacgc acgtataatg ccaagtggag tcttcatttc atgtgaaatt
    25621 gtatctacca actcctttct ttgttccaat agcattcttt ccttatttac atccttttca
    25681 agttgaatat ttgcactttc taggtctgat aatgcctgtt gtagatttgt agacattgta
    25741 ttcaggctcc tagaaagttc tccaaattca tcattagtat ttacagtaca tggattagaa
    25801 aaatcaagtt gggacatact ttttgcagat ttatttatag atgtgattgg ttctgaaata
    25861 aattttccca ataagaaatc aatactcata ataaatataa ccagtattat aaaccaaatc
    25921 caaaattcaa atttagagtt tatcgaaaat tcttcaacaa ccagataaaa taatataatt
    25981 aacgctcctg ataatttaga aagtaaaaac actttttttc taactgaata tagtccaaaa
    26041 ttttgtttaa tccaatttga aatatctaca tttttcagtt tttctataat ctttcttaaa
    26101 ctattcattc cttaacctca aacttatatc ctgaacgaat taatgtaact atatggtgtc
    26161 cttcactacc aagctttttg cgtaaggttt ttatatgtgt atctacagtt cgtgtgtttc
    26221 cttcaaaatc atatccccat atacaattta aaagtttctc tctggaaaaa acttgattag
    26281 ggttttccat aaataaacgc aataattcaa attctttata tgttaaatca atcaatttat
    26341 cttctacata cacttgcctt gatgctacca taataaaaat ctttcctaaa ctcaatgaat
    26401 ttttgggaat atcagtagtg tatctacgta acaaggcatt aacttttgct aaaagtactt
    26461 tggggctaaa tggttttgtt atataatcat ctgcgccata ttcataaccc tttaatttgt
    26521 cctcctcttc acctttagct gtcaatataa taataggtat attagtcatt tcacgtgaaa
    26581 ctctacacac tgaaaatcca tctaaatacg gcatcataat atccaatatc attaaatcta
    26641 tattgttgct ctttaatatt gtaagtgcct cgactccatc atcagcagtt atacaagtat
    26701 atcctccctt ttgcatatat tctacaataa tactttgcat ccttttttca tcttctacaa
    26761 ttagtatttt agccatttct atttatcacc tcttttttgt aggctttatt ttagtttata
    26821 ttaatttatt tatttttcaa ctattttttt atagtatttt gatagtattt ttataatatt
    26881 ttttatagca ttttgatagt attttttaga ctattcttaa tggaattgat atcatagata
    26941 aaaatagcct actaactttt tctatgttag caggctaaaa tatttctaat aataattata
    27001 ttattttgtc actattctat tttttcgatt aaaatatatt ctaaaacaaa tatcttcaat
    27061 taatgaataa attgcacttg ttataaagta cagacctatg gctactggag ttctaacagt
    27121 tagtataaga cttgttatgg tagtcaccac agccatttgt ttgttaaact ttacttgaga
    27181 atttattttt aaatatggta tataattcac taaatttgaa gctaacataa ttaatgtata
    27241 tatacaaggt aatataaaca aattatcaaa tgtacctaaa ttagcaatcc atggaattat
    27301 aattgttgta aattcctttg tcatatctaa acatacatga tataaagcat atactactgg
    27361 catttgaacc aaaactataa gacatcccag catactcttc atactttcta cagaacttac
    27421 ttgtatttgc ttttccaatt ctttagtatc attcttatac ttttctttta tatgttccat
    27481 tttttcagct aattcttgct gttttttaca gaaaatcttt gttttaatga tagtggcata
    27541 agtactaatt taacgattaa agttataagt acaatagaaa ttccaaaatc acctgtaaaa
    27601 ttaaataata tacttaataa tccttgcaat atacttgaaa tgaaatccat tttattctct
    27661 cctttttatt tttaaacttt agaatttata atagattcat ttcaaattaa aacaaactac
    27721 aatacctcca aatatcatat ttctgaaaaa ctatatactg tttaggcaac cgttcttcag
    27781 aatatgtaat tctatttaca aatatgtctc ttattaaaac atacttaatt ttatgattta
    27841 agaggttttt acaaaaataa aatatacttc caatgataga taccaataat gtcatataaa
    27901 ttagtacata taacatacta tccatatcta atctcatcac atcacctctt catcacttat
    27961 atttattttt agacaatttc aagtcctaaa taattccaac atttatattt agttttaaat
    28021 aattatagta tagaaaactc ctaatgtaaa tatatatatt attatattta tcatttttat
    28081 tcgtcatatt tacatttata aagtatataa ttttatcact cttaattttt aataaaaatc
    28141 acctaaagta tttttttttt ctctgaacaa aacaatatta agtttttata gcttattttc
    28201 aaattatagt ccttaattta atataaggct caatataata ataaatctga atatatataa
    28261 atcctaatat atatatctct caatataata ttaaatacaa cctttcatac aattttaaat
    28321 ataatgttta atataatccc ttagtataat cacatacttt ttgatacaat tcttaatata
    28381 atcattaata attgtatact aaaatcaatg actttttttc tgattaatgc taaaataatt
    28441 aaaatagaaa ataaaaatta aatagatttt tccaaaaaat aaacggaggt tacttaaaat
    28501 gataagtgat tctatatcaa aaagacgaag tatcagaaaa tataaaaatc aaagcatttc
    28561 acatgaaact atagagaaaa taattgaagc tggaataaat gcaccttcat ctaaaaacag
    28621 gcaaccatgg cgttttgttg tcatcactga aaaggaaaaa gaatctatgc ttaaagccat
    28681 gagcaaaggt attcaaaatg aaattaatga taatgggctt cttccaggaa gtcgtcaaca
    28741 tatcgctggt gcaaattaca cagttgaaat catgaaacaa gctccagtaa caatttttat
    28801 tttaaatata ttaggtaaat cacctttaga aaagctatcc cctgaagaac gattctatga
    28861 aatggcaaac atgcaatcaa ttggagctgc aattcagaat atgtcgctta cagctgtgga
    28921 attaggtcta ggtagtcttt ggatttgtga tgtatacttt gcatatcgtg aattatgtga
    28981 atggttaaat acagatagtc aattagtggc agcaatatct ttgggttatc ctgatgaaga
    29041 accatcaaga agacctagat tacaattaag tgatgtgact gaatggagat aaatagttgt
    29101 agtaagcaaa tagtgcaaac agaatttata ttatgtgaag tattttgatg aaaaaaatta
    29161 ttaaatcttt tacagtttgg ttttttttaa ttgcattatt tgagatttat atgcatcaaa
    29221 ttggtcaaga ctcaaaaagt attattctaa taggtttaaa tcctattttg tctattattt
    29281 ccagagttga tagttttttt gttttatgga ttcaggtatg caaatcccat gtagaacaat
    29341 tacagggtca atttcgattt attggtacat agcatctata ctttcttttc ttatttatgg
    29401 tataatttta gatttaatta gaatagttat ttccaaaatt ggaaataaaa caaaataatc
    29461 atcataaata gtgcattttc ttgagctatt aaacttcact ggatagagag acataacact
    29521 ctacaacata tacttagctt cagaaaatgc acctttaaat cttcatatga acattatttt
    29581 acttacatta atttaatgtt acttaaaaat taatgtattg tatttcttta aattaatttt
    29641 ctatatttct taaattagtt tat
//
LOCUS       DAEPUT010000233        15199 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.guided.098, whole genome shotgun sequence.
ACCESSION   DAEPUT010000233 DAEPUT010000000
VERSION     DAEPUT010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.guided.098"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="KRL22_004018"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="KRL22_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH1274392.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEDAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMI
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="KRL22_004019"
     CDS             1575..2258
                     /locus_tag="KRL22_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1274393.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..4915
                     /locus_tag="KRL22_004020"
     CDS             2255..4915
                     /locus_tag="KRL22_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1274394.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVISAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYINSGNYHADAPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5096..6277)
                     /locus_tag="KRL22_004021"
     CDS             complement(5096..6277)
                     /locus_tag="KRL22_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1274395.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESILLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTIHAENCHNGGARFIIKFY
                     T"
     gene            complement(6277..6939)
                     /locus_tag="KRL22_004022"
     CDS             complement(6277..6939)
                     /locus_tag="KRL22_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1274396.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTPGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            complement(7071..7709)
                     /locus_tag="KRL22_004023"
     CDS             complement(7071..7709)
                     /locus_tag="KRL22_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1274397.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            7888..8493
                     /locus_tag="KRL22_004024"
     CDS             7888..8493
                     /locus_tag="KRL22_004024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1274398.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGENIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            8997..9746
                     /locus_tag="KRL22_004025"
     CDS             8997..9746
                     /locus_tag="KRL22_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1274399.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRICRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            9743..10507
                     /locus_tag="KRL22_004026"
     CDS             9743..10507
                     /locus_tag="KRL22_004026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1274400.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEIKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            10606..11427
                     /locus_tag="KRL22_004027"
     CDS             10606..11427
                     /locus_tag="KRL22_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1274401.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVAQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            11441..13105
                     /locus_tag="KRL22_004028"
     CDS             11441..13105
                     /locus_tag="KRL22_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBH1274402.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKNLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESEDVIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDVNLLNKTVRLKPFHAVLLKAR"
     gene            13110..14984
                     /locus_tag="KRL22_004029"
     CDS             13110..14984
                     /locus_tag="KRL22_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1274403.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
BASE COUNT         5709 a         1735 c         2531 g         5224 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacctaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtatact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaataa taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagatgca tttaaggagt cttgtgtttg gtactacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaata ttttagatga tttaaagtat gggaattgtg atattagcga
      841 atgggaagga gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atgtaaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgatagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg aatctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac tcttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga agatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatctatag accagctatt ttattagcag atgagccaac tggtaatctt gatagaaaaa
     2101 attcagaaga aattgtagac ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataaa
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg aattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggagatag aatcctaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gaggctacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatatctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttgggatgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcagttagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg atttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtctatatta attcaggtaa
     3361 ttatcatgct gatgctccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaaaatatct cctatagagg caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgcaaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctgtagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatgtctgct tccacttggt tgactgaaaa agatgcttca aaagaacttg cgaaaaatgg
     3901 aggatttaaa aatatagctt catctaaaaa gtactctcct atagaacgtg atggcaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtaggca
     4021 aatttctgta gacccaaagt tattttatga tacaaaaaat ccaacctcaa ttgtatataa
     4081 taaggaggaa gatattaatc gtagtacacg tagaaataaa gtatatatag attatttaaa
     4141 tctttcaata ggagataaca ttaaattaaa tgaaaaagta tatgacgaag ataaagggga
     4201 ttatacttac aacatgaaag tgggagctat tacaagcaca cttcctaaaa tagtagatac
     4261 tagttcaaag tatacattaa tgcaaatagt tccaatgtct atggtgcagg aaatatctaa
     4321 aaattatgat gaagtaagta ggttacgttc aaataggctg ataggagtat ttaaagtaaa
     4381 taatcgtgag gacattccta gagtaagaga aaaattagag tccatttata ataaagacta
     4441 tggttcagga gattatagta ttgaggatgt tttagaaagt gaaaaacaaa aggctagtgg
     4501 aataaagacc atgaatttaa tagtaggctt tattacaggt ttattggcta tgattggatt
     4561 atcaaatgta cttgctacag tgtcaggaaa tattagaagt agacgacaag agtttgctat
     4621 gttgcgttct gttggattat ctccagaagg cataaaaaag atgcttattt tggaaggttt
     4681 attcttagga attacaccat tactacttag tattcctgtg caaataggaa tagtgtatgc
     4741 ttttctacgt ataaatgaaa tatattttat agagtattta ccatttgcac ctatatctac
     4801 aataataggt tttactatat tgatactttt tattgtaata gcatcatata tgacaggata
     4861 caagcagttg aagaatgaaa atatagtaga atctataaaa aatgaaacaa tataaacaaa
     4921 atctatttga acttatttaa aggtttcgat ttaagactac ttacaagtat agggatagtt
     4981 aagttgtttg tttaataaaa ccttaaatgt aaatagaagt atattactaa aacaatagat
     5041 aacatagaat atagatatag ctggattata ggtattttac ctataatcca gcattttatg
     5101 tgtaaaattt aattatgaat cttgcaccac cattatggca attttctgca tgtatagtac
     5161 cattttgacg ttctataata gactttgata gagcaagccc tataccaata ctgtccttac
     5221 tagcattttt accacgataa aatctattaa aaatatatgg aagttcttcc tgagcaaacc
     5281 ccttaccatt atcttctatg ataatctcaa catatagagg attttgacta taataagcaa
     5341 ctatatatcc accatcttct atatgctcac tacaattttt aagaatattt aaaagagctt
     5401 ctaaagtcca attaatatcg atttcaaatt ctaccgaagg agaagcctcg atagtaaatg
     5461 tctgatgttt ttctcttaaa gaaccttcta taggctcaat tgcataagta agaagagaat
     5521 gtacatctat aagtttgctt tcaaatatta aagtacttgc atccaatttt gataatgtaa
     5581 gtaaagatga aactagtctc tcaagtcttg agatttgatt tgtaagtctg ttaatataat
     5641 ctatttcttc atctggacaa ttttctgaaa gtaattgtgc cataagtgac atagaagtaa
     5701 ttggagtctt aagttgatga gcaatatctg caaggttatc tgaaagagtt tgtctttctt
     5761 ttaaagcaaa ttcttttgaa caacgaagtt ccccaactgt tttatatatc tcatcttcaa
     5821 ggtgagaaaa ttcatcttca catcgtaaaa gtatagactc ttttcctaaa ttcacttctt
     5881 ctaagtattg agtaagattg tttattctac tcagtttttg cttatttgtt ctatgtttga
     5941 ttatatatac aactgtagcc attgttgaaa ttataccaaa cgatatcact agaaaataaa
     6001 aaaagttttt actccaaaat gtacttttag aatatccatg ttttgataaa atttcatttc
     6061 ctgttttaaa atccttatca ctagaatttt tcagtgattt tagtatactt tctgtagact
     6121 taggattgta ctcatatgat gcaccaagag ccttagacag tacattgtat tcattaaaag
     6181 aagttatagt tgttagaatt acactcaata aaaaagttac aattaagcag aatattataa
     6241 aaacaactgt actgttgata tttcttggag ttttcactag ttgtcctcca ttctatatcc
     6301 tatgcctctt aatgttttta tacaaggtgg attttttaat ttttctctaa gacgttttat
     6361 tgtaacagta agagtgttat catttacgaa attaccatct acatcccaga gcatttctag
     6421 taactttgta cgagtcatag ctctattttt attttccata agacttagaa gaagtttata
     6481 ttctcctggt gtcaaaggta cttcaacatt atctaaatat gctttgactt caaccttatt
     6541 caagcttata ttttcacatg taatagtatt gttagtattt gaatgagttc ttctaagaac
     6601 tgcattaatt ctggattgaa gtactgagag caaaaacggt ttaaccacat agtcatctgc
     6661 acccatatct aatccacgta taatgtcttt ttcatcatca cggactgtca aaaatatcac
     6721 tggagtatct tctatacttt taacatattg gcaaaactcg tatccaatac catcaggtag
     6781 atttaaatca agcagaatta aatcaatagt tttatcaaaa ttttttttag cttcagcaat
     6841 cgtattataa caacatacag tgtgattttt cttttcaagg gaagttttta ttccaaatgt
     6901 aattgtatca tcatcttcta aaagaagtat tttagccatt tacttttaat cctttcagta
     6961 atttagttat tccattaact aagttattag ttttatgttt aatatttttt atattagaga
     7021 tagaaaaaat tatcatttaa gtatataaac tttaatttat aaacttaggt ttatgcttta
     7081 attgaatcta ttaaaagagc aagagttgtt tcaataaatt tttcctcatc tatattaaag
     7141 ttgttcaggt atgattttcc tgttacagat agtaaattaa aaaatcctgt aagtgtaaat
     7201 attgatgaat acataagagt aggtatttca atatcatgcc taatacttct atcatttttt
     7261 ccaatttcaa acattccttg tatttcatca aacataaatt tgttaaaaga aaaaaacttt
     7321 tctttaaaca gcatatcagt atccgatttt tcagagttta caataccaat cattcccata
     7381 aggcataata gagaaggttc tacagagtaa aatttatgaa aagcaaagta tgaaagtttt
     7441 attttttcaa accctgtttt gccttttgca ctttctattt taacattatc ccaaagtctt
     7501 ttatatcctc ttaagacaac agcaaagaat aaatcttctt tacatgaaaa gtacttgtat
     7561 atggtgcgtt tagtatattc aacttctttt gctaattcat tcatagttgt attatcaaat
     7621 ccattaagac aaaataattt ttctgcctta tcaataatct cattttctct ttgtattttt
     7681 tctttatctc tttttgataa ttctgacata taaattattc ctttctattg ataaaaaagt
     7741 atactgatgg tatatttatg taaatataat atttgtatac ctatagtata ctttaataaa
     7801 aaataaaatt aatatcaagt attataacta tttataactt tattaattaa ttatataggt
     7861 aaaataccaa ataaggggaa tttatttatg aagataaaag aaaatgtatt aatgttagat
     7921 agtactcgtg gctcaaattg ttttattgtg tttgataaag aaattattct tatagacaca
     7981 ggtcttcctt ttatggggga aaatataatt aaagaattaa aaacacttgg cattaaactt
     8041 acagatatta agcatatttt attaactcat catgatgttg accatatatc taatattaaa
     8101 ttattgaaag aaaaaacagg agcaaaagta tgggctcatg tagaggatat accttttatt
     8161 ataggagaga aggatagacc tgggtttaag aagtttattg gaaaggcaat ttccagaagg
     8221 ctcattaagg atgttgaacc ttatggagag aatatgcaga ttgggaatat aaaaattatc
     8281 catactcctg gtcatactcc agggcatgtc tgcatgattt ttgaagatgt attatttgca
     8341 ggtgatttag tcaaaaataa gaatggaaat atagttcctt atcctaatcc atggaattgg
     8401 gattataaaa agatgatgaa atctataaga gaattggata atttaaaata tgaatggata
     8461 tgtatgtctc atggaactcc ttgtattaaa taataaaaat taacatggat taatagaggc
     8521 gtagttgctt gtatgtatga taataattta cagcttcttt ttaatatatc atgtatattt
     8581 gtagctgtaa gcatatttat aacaatactt acaattttgt attttaacat ctataataat
     8641 agttttagct ttgttaacta tgaaatttac ttaaagaagt aaatattcaa gtaatagtaa
     8701 ttattaaata agataaaaag taaatggcag atgaattaaa gtaatttcta ccatggaaaa
     8761 cacttttgag ttagaaaaaa ctatatttta gagtatgaag agatgaagct tctgaagaaa
     8821 gcaatatcta aagtacatgt tcgaaaggat aagtactttt tggtgcctgc ttttagcagg
     8881 ttatttttat tttaataaaa ataaaatcaa atgattattt tatccttatt atttaaaact
     8941 cttccctaga aaaagcaact aatgtatatt aaaataatat ttagggagtg gaaaaaatga
     9001 gattagaatc gttagttaac caaaattatg ataatttaaa tgaaaatgat aaaattatta
     9061 ttaaacaaat attgatttgt caaagagaat accgtaattt ttcgtgtgaa aaaattgcaa
     9121 atgaatgtaa tgtttctaga gctactttat taaggatttg tagaaaaatt ggattagatt
     9181 cattctctga tttaaagtat ttacttaaaa ataatcaact agaatttgtt aataatgata
     9241 ataattttca tgatgtttgc gagaattatc gactattaat gaatgaatta caaaaaatat
     9301 catttcaaga tatttgtaaa ataatatatg atgcagaaac aatttatatt tatgggacag
     9361 gtaatgaaca gaaaagttta gctcaagaaa taaagagaat atttctttca gtaggtaaat
     9421 gtgttattga cttatttgat ataggtgaaa ttgaatttat gagagaatca tttcaaaaaa
     9481 gtgatttatt tattatcatt tctttgtctg gagaaacaaa agcaggaatt gaaattgcaa
     9541 aatttatcaa caatcatata catacgattt ctttaactag gcttgataat aatacaattg
     9601 caacactttg tgagtataat ctgtatgttg aaacgcaaaa acttgataca ttacaagcta
     9661 tatcttatga agtcgtagga gcattttatg ctctattaga tttgcttcat atgaattaca
     9721 tagagtatag aaggagaaaa gaatgaaaat tgaaggactt ttcaataaat attataattc
     9781 atttacagca aatgataagt atatctgtga gtgtattctt aatcataaag aagattgtat
     9841 taaactttct atagatgaat ttgcagacaa ataccatata tctacaagtg cactttctcg
     9901 ttttgctcaa aaactacaat tacctggata tagtgaatta agagttatta tacgcttaaa
     9961 tgaaacagaa gtagaatata aaaatcaaag taaacatcaa ttaatggatt gttataataa
    10021 ggtgatagat gatatagaga agaaggattg ttcgattatg tttgaaagaa tgaaaaaggc
    10081 aaatcgtata atcgtctttg gagaaggtta ttctcaggaa agagttgcta aagagataaa
    10141 aaggattttc ttaccaacag ggaaaattat atatgatgtt tatggttatg atatgattca
    10201 ggcacttaat cattttataa aaacagatga tatgattttc tttatttcat tgaatggaga
    10261 tgcatctaca attattgatt ttgctaaaga aatgagaatg aaaggaattt atatggtttc
    10321 tattacaaaa atgataagta atcctttagc aagattatgt gatgaaaacc tgtatattca
    10381 atctatatct atttctgtag ataaacaact ggactacgat gtaacaacac cttattttat
    10441 tttaattgaa ctgctttata ttaaatacaa gatgtattta gaaagtgaac atattccccg
    10501 aaaatgaaaa tttgtgctaa aaatgaacat attttttaaa agatatcaaa atattgatat
    10561 cttttttttt gaatgctatt atgattttga tagtaagaaa ggaagatgaa attgtacaaa
    10621 ttattaatac ttgatataga tggtacgctt agagatgagg tatatggaat cccagaatct
    10681 gcaaagcatg ctatacgttt atgtcaaaag aatcattgca gtgttgttat ttgtactgga
    10741 agaagtatgg gtacaataca agatgatgtt ttatcattag gagttgatgg atatattgca
    10801 ggaggaggta attacattca atatcatggt gaattacttt ataatcaatc ttttaatcaa
    10861 agattgataa aggaagttgt ttgtttatta aaaaagagag aagttgcttt ttcgattgag
    10921 agtcaggaaa aagttttcat gaatcaaaaa gccaaagaaa tatttgaaac aatgaatcag
    10981 ttgaaaggaa ctaattcttg tataaataaa caacatatcc aagaaaaaat aacatatgaa
    11041 aataacattg aagagtataa gtcacaagat atacataaaa tttgtttatg gtcaaatgaa
    11101 aaggtatttg acgaagtgaa agatatacta caagataaaa tggaattagc acagagagat
    11161 atttctagtc agtattatga aattattcaa aaagattttc ataagggcaa agcaattaag
    11221 agattacaag aaagattagg agtagctcaa aaagaaacca tatgttttgg tgatggtcaa
    11281 aatgacattg tcatgtttca agcatcagac gttacaattg caatgaaaaa tagtcatcaa
    11341 caacttaaag atatagcgac atctatatgt gaggacatat tcgataatgg aatttataaa
    11401 gaattaaaaa gaagaaatat catataaaaa ggagtaattt atggaaaaga aatggtggca
    11461 aaaagaaatc gtttatcaaa tttatccaag aagctttcaa gatagtaata atgatggaat
    11521 tggagattta cagggaatta tttctcgttt agattattta aaaaatttag gtattacatc
    11581 attgtggtta tgtccaattt ttaaatcacc tatggacgat aatgggtatg atattagtga
    11641 ttatttggat attgcaagtg aatttggaag tatggaagat ttaaaagagt taattaaaga
    11701 aagtaaagat agaggaatca aaattatatt agatttagtt cttaatcata caagtgatga
    11761 acatccttgg tttcaagaag cattaaaaaa tccagaaagt ccttatcatg attattatat
    11821 ttttaaaaaa ggaaacgatt taccaaataa ctggaggtct gtttttggtg gaagtgtttg
    11881 ggaaaaggta gagaatagag acgaatatta ttttcattct tttggtaaaa aacaacctga
    11941 ccttaattgg gaaaatccaa tattaagaag tgaactttac caaatgatta atacctggtc
    12001 tcaaatggga gtggcaggat ttagagttga tgctattaca ttcatcaaaa agaatttaag
    12061 ttttcaaagt ttagaaagtg atggtgttga tggtcttgtt aaatgtacaa aaacagttag
    12121 aaatcagcct ggaatagaaa aaatgcttta tgaattaaaa gaaaatacgt ttaaaaaata
    12181 tgattgtatg actgttgctg aagcagcagg tattagctat gaccagttag gtgattttat
    12241 tggagaagat ggtttctttt caatggtctt tgactttaaa catgctgact tagatgttgc
    12301 ttctggtagt gagtggttta aaagaatttc atggacaatt ccagatttaa gaaaatgcat
    12361 tttagatagt caaatgtatg ttcaggaaca tggatgggca gctaatttta ttgaaaatca
    12421 tgaccaacca agagctacaa caaagtatct tttgcaatac gaaaggaatg atgatgcagt
    12481 aaaaatgttg ggagcaatgt atttcttttt aagaggaacc ccatttattt atcaggggca
    12541 ggaattagga atgacaaatt ttaaaagaga taccataaat gattttaatg atttatctag
    12601 cattgaccaa tactatcgtt caatagatga aggttactca gaagaagaag cgttagaatt
    12661 tgtgaattta agaagccgag ataatgcaag aacgccattt ccatgggcag ataaagaaaa
    12721 tgcaggtttt tcagatacaa caccatggtt aaaggttatt gaaaattata aagatattaa
    12781 tgcacagagt cagattaaca attcagagag tattttagaa ttttataaaa agatgataaa
    12841 gttgagacaa gatagtgagt attctgattg tttgatttat ggttcaatag aacctattga
    12901 tatagaaagt gaagatgtta ttgcgtatag aaggcaatta gatttggtag ttattgattg
    12961 ttattataat ttttctgata aacctgtaga aataagagta gaagaaaaat atgatattgt
    13021 attccaaaat ttagatgatg taaatctatt aaataaaaca gtgcgtttga aaccatttca
    13081 tgcagtatta ttgaaagcga ggtagaaaaa tgaataaata taataaaata gcaaatgagc
    13141 ttattaaaat tattggtgaa gataatatta tttctattac acattgtgcc acaagattaa
    13201 gagtgatggt taaagataga gaaattatta atgataagaa agttgaaaaa gttgatgagg
    13261 ttaaaggggt tttctttact tctggacagt atcaaattat tttaggaaca ggaatagtta
    13321 ataaagttta tgcagaagtt gaaaaaatgg gattaaaaac tttatcaaaa aaagaacaag
    13381 atgaattagt taaaaataat gaaactggat ttaagaaagt tatgagaact ctagcagata
    13441 tatttgttcc tattattcca gttattgcag caacaggatt attcttggga ttaaagggtt
    13501 gtttgtttaa tgataatgta cttggattat ttggaatgtc ttctgcaaat attccattgt
    13561 atattcagac acttgtttca gttcttacag aaacagcatt tgctttttta ccagcaatta
    13621 ttgtatggtc agcatttaaa gtatttggag gaacacctgt tattggactt gttattggac
    13681 ttatgttagt ttccccaata cttcctaatg catattctgt tgctgaccca tcaaatgaaa
    13741 ttgaagcaat tatggcattt ggatttattc ctattgtagg ttgtcaagga agtgttttaa
    13801 cagctattgt tacagcattt attggagcta atcttgaaaa atggttccgt aaacatatgc
    13861 ctaatgtatt agaccttatt ttcacaccat tttttgttat gctaataaca atgttagtta
    13921 ttttgttagg tgtaggccct ataatgcata caatagaatt aaaaatggtt gatatcatca
    13981 gcttattgat tgatttgcct ttaggaattg gaggatttat tattggattt acatatccat
    14041 tagctgttat tactggctta catcatactt atgtaatgat tgaaacatca ctattagcaa
    14101 atacaggatt taatgccctt attactcttt gtgcaatgta tggatttgcg aatattggaa
    14161 catgtctagc atttatgaaa aaatctaaaa ataatcaagt taaacaaact gcggttggag
    14221 caatgttatc tcaacttttt ggtataagtg agcctgtttt atttgggatt cagcttcgat
    14281 ataatttaaa gcctttgatt attatgtgtg catcttcagg tttaggagca gcaatattat
    14341 caattttaca tattcaatct aattcatatg gattagcagt tttaccttct tatttaatgt
    14401 atatctatga tggatataat ttaatcacat acttattagt atcaatattt gtggttgcat
    14461 tctgctttat tgtaacatgt ttatttggag tgcctaaaga agctataaat gaagatgaag
    14521 acgaagaatt agtgtttaat gaaaataatg aaaactttgt gtctccagct aaagggaaaa
    14581 ttgttgcatt agaaaatgta ccagatgaaa cattttctaa aaaaatgtta ggtgatggtt
    14641 ttgctattga tattatagat ggaaaaattg tttctcctat ttcaggtaaa ttagaaacag
    14701 tgttttcaag tggacatgca tttgggatta aaggaactaa tggagaagta ttaattcatg
    14761 ttggaattga tacagttgca ttaaatggag atggctttga tgttgctgtt aaacaaggag
    14821 atatggttaa acagggggat gttcttgtta atgttgattt aaagagaata cacgaattag
    14881 gaaagtctac tttgacaatg gtattgtttc cagatggtaa gaaggtaaat attttggata
    14941 taaacaagga tgtaaaaata ggtcaaagaa tatgtgttga gtagtaggtg atatgtaatg
    15001 actacaaaag aagattatca agattaattc aatcttttta aagtatgaga aataattcat
    15061 aaactctaaa acaattaaag aagttgtttc aaaatagaga ttgtattgca cccaaattgt
    15121 tgaaatgatg aaaatatatt taacttcata caaaaaatta aatagtggca acaattgagg
    15181 atgtgaggga gagttgcca
//
LOCUS       DAEPUT010000234        11379 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.guided.118, whole genome shotgun sequence.
ACCESSION   DAEPUT010000234 DAEPUT010000000
VERSION     DAEPUT010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11379
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.guided.118"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            195..872
                     /locus_tag="KRL22_004030"
     CDS             195..872
                     /locus_tag="KRL22_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274404.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(1205..1972)
                     /locus_tag="KRL22_004031"
     CDS             complement(1205..1972)
                     /locus_tag="KRL22_004031"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBH1274405.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(2642..3457)
                     /locus_tag="KRL22_004032"
                     /pseudo
     CDS             complement(2642..3457)
                     /locus_tag="KRL22_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            3558..4256
                     /locus_tag="KRL22_004033"
     CDS             3558..4256
                     /locus_tag="KRL22_004033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1274406.1"
                     /translation="MYKLSYVVRVSTKNLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFGATQTLGEHEDIYLGYNLDTGKNVYLK
                     PALASQGVKGSITNALASAFIGSLGGGKLFSNNMLVYYAVLFGGQAVIVDPKAKRGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKKDSESLAIDILTFLTGISSRDSD
                     KFLQKNDNWKIIME"
     gene            4344..4964
                     /locus_tag="KRL22_004034"
     CDS             4344..4964
                     /locus_tag="KRL22_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1274407.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            5120..5902
                     /locus_tag="KRL22_004035"
     CDS             5120..5902
                     /locus_tag="KRL22_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBH1274408.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            6027..6953
                     /locus_tag="KRL22_004036"
     CDS             6027..6953
                     /locus_tag="KRL22_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1274409.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            6967..7416
                     /locus_tag="KRL22_004037"
                     /pseudo
     CDS             6967..7416
                     /locus_tag="KRL22_004037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            7775..8182
                     /locus_tag="KRL22_004038"
     CDS             7775..8182
                     /locus_tag="KRL22_004038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1274410.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRINDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKKLKELMEEH"
     gene            8184..8414
                     /locus_tag="KRL22_004039"
     CDS             8184..8414
                     /locus_tag="KRL22_004039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1274411.1"
                     /translation="MKPTKEVLPFTIILLAVHSDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            8804..9007
                     /locus_tag="KRL22_004040"
     CDS             8804..9007
                     /locus_tag="KRL22_004040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1274412.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            9085..9438
                     /locus_tag="KRL22_004041"
     CDS             9085..9438
                     /locus_tag="KRL22_004041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH1274413.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNVLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            9510..10142
                     /locus_tag="KRL22_004042"
     CDS             9510..10142
                     /locus_tag="KRL22_004042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH1274414.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(10512..11369)
                     /locus_tag="KRL22_004043"
     CDS             complement(10512..11369)
                     /locus_tag="KRL22_004043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012423863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1274415.1"
                     /translation="MPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIKPLEV
                     IKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYGSPKS
                     IEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKSGIKL
                     SATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGEFTIL
                     EDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYLSNQK
                     LKREEYRRL"
BASE COUNT         4057 a         1670 c         1727 g         3925 t
ORIGIN      
        1 ttgaaaatgc tgatagatac tgtgttttag cggataatca actttttagt atgttttttt
       61 attaaaaaaa aggttatttg aaataaataa cctttttttg tctttttgtg ttaacattgt
      121 cttatagtgc taatgagtac tattagacca tgttctatgg ccttatttta atataaaacg
      181 attggagata ggctatgatt gtgattgaag gtagcgataa atttaagatt gcaaaagaat
      241 atattgatgt agaatatact ctttttagca aagtaacttt taggtatgaa aagttgaaat
      301 ttaaagataa tgctgaattg gaaaaaatta agatgtttaa atataaaaat ggctacatcc
      361 ctaataaatt aaacctttct tttggatatg gattctcttc ttataaaaag caaataatta
      421 gagaaactgt agatacttta agattgacag aaattttttc aagcgagaac atagaagata
      481 ttaaatttat aaaagatggt acaaaaaaat tagaaattag catagagaaa gttgtgaaat
      541 ttaaacgtcg aaaaaaaaga aattatgttt gttgctattg ccctgatatg tatagggaca
      601 taaaactcga caaagaatct atcaataaga tatacaacag aaaaataaaa atagaaagag
      661 aagttaatat ttttgaagat gaggatgtta taataaacaa aaaagtattg aagtttccaa
      721 agtcttggac aaagaatatg caaaaatatt ggttaagtga aaataagtat cccatacatt
      781 ctactgtaat tgatgatgat agatataaat gttgtaatgt acaatataca aaaaatagag
      841 tgataatatt atattacata tataaccatt aatatacata attacaaaaa aataatgaca
      901 aatatacata atacaaatat atcttctact ttagataaaa cagttattat gaaaacttac
      961 tatctataaa taatagaaat gctagtatac catctataat ctaatgtcta gtaggtttta
     1021 atggcatatt ttaaatatgc catagttgat ttataagatt ttctatatca ctttcaaaat
     1081 acacactaaa tagttgcttt tcagatataa ttgcccaatt taaattttac tatctgaaaa
     1141 gttttttata tttaatttat atcttcaaaa ataaaatacc ttctaatatt tctatataat
     1201 taatttaatt aatactctta tgtaatagat taagtactga atttaactct ttaaatgata
     1261 tttgtcctgg tgctgaaaca ctttttgcag ctccaaaagt caatgcagaa ccaaatattt
     1321 caccacacaa tctacttata acacccattc ctgacattga cattgttatt attggtctat
     1381 ctgcataaat tttaaacatt tcatttgtag cttcaagtag cactaacaca tctttttcat
     1441 tttgcggcat aacagctatt ttgggtaaat ctgcgcccaa ttcctgcatt ctacataaac
     1501 gagatacaat ctcttctttt tttggagttt tattaaaatc atgattagat ataattactt
     1561 tcacttcttt tttatgagca aaattaacta cttcatctat gacctcatct cccataaata
     1621 actctacatc tattaaatct actaaacctg tattagaaat ttctttattc aaagtagtat
     1681 aataatctct tgatattaat ttttctcccc cttctactac acttctaaat gtgaataata
     1741 aagggatatc atgtatataa cttcttaatt catagagaac ttccttaact tctttaatat
     1801 tttctacatt ctcaaaaaaa tcaactcgcc actctataat atccaaacat gcatctttta
     1861 actctttagc ctcttttata atatcttttt tatttttccc aataattggt acacaaattt
     1921 taggtctacc ttctccaata gtaatatttt ttacttgaac ttttcttttc atattctcct
     1981 ccataatcag aaattctata ggactttaaa ttctattttc tgcacaattt aattatacat
     2041 taaaaatact atacattata aaaatactaa tttaaaaata atttttattc taattcttaa
     2101 aacaatccca catattttag aaaaggtact ctataatata caaacacttt ttttacctaa
     2161 atttatttta acattctata attttcacaa tattctttaa attttactca tataaacaat
     2221 attattctgg atgctaatag aattaatcta taaatcatag tataattatg cagaaataac
     2281 tcgaatttca ctacttatga agagattgaa tattaatgaa tctaaatcat ttgcattatt
     2341 taagagtttt gactaaagtt gaacaccata caaaagtagc tactcaattg tttatacccc
     2401 aaccaagctt aagtaatgtt atatagattc tctaaaaaga atttagtatc tttttatttg
     2461 aaaaacttat attaaatttg attatctttt cataagttgg taaatgtcga tatatcctgt
     2521 atctacaagg agtatcggca ttttctcttt ggaagatact ttgcataagt tggcatttaa
     2581 ccgtataaga atgccatcaa aagtagtaaa taagtagtaa actctagtca tactactagg
     2641 cttataaccg ttccatttca gctctcgcag aactaaatga accatgtgca taatagccaa
     2701 gcgtcatagt aatgttttta tgccccataa tatattgcaa tatattagga ctcattcctt
     2761 tgttagccat atttgtacag agtgtatgca taaagatata tggcgtaatc tttggtagct
     2821 tgtcctcatg ggtcttgtta tacttcttga ctaacgctct taacatgctt tgataatgag
     2881 ttgcttgttt tggtaatcca tcttgtttaa gaaataggaa gttctggtaa ccatcaacaa
     2941 tgattggttc tgctttagcg ttcttacgcc gttccacgat acgttcaaat gattgataag
     3001 ctctttcagt cattggaatt tctcgcttac cctgtgtggt ctttggaact tctacataat
     3061 agccaatctt agtatcactc aacaattgat ggtctaccat aatggcttta tttttcatat
     3121 ccaattctaa agtcaaaccg cataattcag aaatgcgtag tcctgtttct aagaggataa
     3181 caacatcatc ataatattta caataagtct tatcgctccc cataaaggat aataagccca
     3241 tttcctgttc tggtgttaga gcgatttttg gttctgttgt atcttccaaa acatcactta
     3301 actaaaaatt aaatggattc tttctaatac agtcgtcttg aattgccatg aaaaacgacg
     3361 ctttcagtga gcgcttataa ttgtcaatgg atttataagc acacccatct tcactcattc
     3421 ggatagccca gcttttagcg tctgataatt taaccatatc aatgcttttt gcacctagtg
     3481 ggtcattgat agtatctata ttttgattta taatttatac atttttttaa aaacagactt
     3541 ttaactgtaa agaatctatg tataaactta gctatgttgt ccgtgtatct acaaagaatc
     3601 ttgacgagct aaaaaggcgt tgtgatgaag tcaaagactt ttacgacgac ttatcaatca
     3661 agctcgtgcg tccctttggg gatatgttgg gattgcatgg cgaatttatt cctgtcagca
     3721 aacgttacat caatgattat attcaatatg tcacttcgga ttttttggct ggacttggtt
     3781 ttggagcgac acaaaccctt ggcgaacatg aggatatcta tcttggctac aatctggaca
     3841 ctggaaagaa tgtctatcta aaacctgccc ttgctagtca aggggtaaag ggttctatta
     3901 ccaatgcgtt agcgtctgcg tttatcggtt cattgggtgg tggtaaatta ttcagtaaca
     3961 atatgcttgt ttactatgcg gtactattcg gcggacaggc ggtcatagtt gaccctaaag
     4021 caaaacgcgg caaatggaaa gaaacgctac cagaaatagc ccatgagata aacattgtca
     4081 atttaaccag taatgatgaa aacaaagggt tgcttgaccc ttacgtcatt ttgagccgta
     4141 aaaaggattc tgaaagttta gcgattgata tcctaacatt ccttactggt atctccagtc
     4201 gtgacagtga taagtttttg cagaaaaatg acaactggaa aataataatg gaatagtttc
     4261 tatgtaaata tatttttact atcttaccta actaattgaa agatgatata atttaatcaa
     4321 agatttggta aggagggatg aatatgcatt taattgattt tatgaatgaa gatattaaaa
     4381 agaagcttgt taaaaaaacg tataaaaaga aagagactat tctttttgct gagcaagaaa
     4441 atgaatatgt aattcttatg attgacggta ttgcagaagc attcatctta aatgtgaaag
     4501 gaaacatctc aacgattcat ctttatagaa gtggtagttt ttttggagaa atggaacaat
     4561 ttaatgatgg gaaaaaaccc gttgaaattg tcgctttcac agattgtaat gtatataaac
     4621 ttcatagaga tgatttttta aactggttaa ggggagattt tgaagctaca aaatttctga
     4681 ttcgagaaat atctagtaaa ttagttgtaa atgctgaatt aattgaagaa ttatcatctt
     4741 taagtgttaa agaacgactt ctgaggtgta tatccttaca ctattataga agtgaattaa
     4801 atctgcttac caaaaaacag cttgctagcg aagtaaacgc tccaattaga agcattaatc
     4861 gtgctataaa tgaatgtgta caagaacatc taattgctta tgaaaacaaa agatttagtg
     4921 taattaatca gcgagaggta ttaaagaatc ttcctacaac ataagtataa tttcaaaaaa
     4981 gtattgaata ataattattc aatgcttttt tatttcgggt caagtgacct attttttttt
     5041 atttcttcat tatataatac tcctatgcat aattatgttg gattgatagc taataaaaga
     5101 cagtgagagg tgttatatta tgactaaaac acaacagaaa atgatacaaa acgtattaga
     5161 attttcaaaa agagatagta ggataatagg acttgcaatt agcggttctt atatcacaaa
     5221 atcgttagat gaatattctg atttggattt tctgattgta gcagatgata aatcctatga
     5281 agaagttatc gaagagagat tacttattgt ggaacagttt ggaacattag tttctgcttt
     5341 tactggcgaa cacgttggag aacctcgatt gataatttcc ctctatgatt cccctgttct
     5401 tcatgttgat tttaagttta caaccttaga tggtttacta gatagggttg aagattcagc
     5461 tattctctat gaagaaaaca actgcataac agaaatttat tctaaaaaag aagcatactt
     5521 cccaactcca gacttacagt ggattgaaga tagattttgg atttgggttc attacgcttg
     5581 cactaagatt ggacgtagag aactatttga aacaattgat tttttatctt ttttaagaca
     5641 atcagtactt gccccattaa tacagcttct cttaggtaaa ttacctcgtg gagttagaaa
     5701 aattgaattg gacgcacccc aatatattga agcattagaa aagacggttg ctaaccatga
     5761 atataaaagc tgtgttaatg cattgcaggc tactatcaac ctgtatcttg agttaagaga
     5821 ggaattatca caaagtccta ttgtccgaaa ggttgaagct gaaagggttg cattacagta
     5881 ttttcaagat ttaatcaaat aaacccaaag taaaaaaata ttgaatagta aatattcagt
     5941 gttttttcat ttttggtcaa atgacctaga ttagttgttg taacaattct ataattattt
     6001 tgaaagtaac agtatggagg ataactatga gtgatatttt aagtagaatt acaaataaaa
     6061 ttggggataa gaatatagtt gataagttat cagctctatc aaaatcagat ttgaactcac
     6121 ttctattaga agtgtttgat agacaagcaa atactttaac tgcaactgat attctaaagt
     6181 cataccaact aaatagattt actatcccta gcggtataga tccagaagaa attcatgctt
     6241 tggagtcaaa attattgaga aaagcattca atatggatat caagacgatt atgctttctc
     6301 cctctgctcc attaggtagc tgtagcgttt ttggctccgt agatcaatat aatgtagtaa
     6361 gtgctctacg agggacagaa acacttgcag acccctcaaa tatgttggca ataattattg
     6421 ctgataaatt aaaaagaaaa gaagaaaata ataccatacc tatccacatg gctactactg
     6481 ctagggtaat aagagcacaa aattttgtag gtaaaggttt atattcacat tttggcttat
     6541 attgtatggt ttcatctggt atagatacag ggtcttacac ttgtgaaaaa atgttgttag
     6601 aaaagcactt aaactattat aaagatatat taagtgaaat agaaaatgtt cgtttctcta
     6661 ttattctacg caaaagaaac ggatacaaag ataatgacgg atttttcgac agaatggttg
     6721 aaactatcaa acttattttt cctaatatag agttatcaat tcataatgat gatgttgata
     6781 ataattatta taaaggtatc aatttcaaat tatcggtcaa acaaggaaat gaaaccgttg
     6841 aaatagttga cggtggattt gttgactgga cttatcaaat gcttggaaat aaaaaagaac
     6901 gctgtttgat aagtggtatt ggcttagaaa gatttcttgt agctgtttca taaaaggaga
     6961 agaaaaatgg aacttataga gtggaattat gcttatatta ccgatttagt tgagtttgcg
     7021 aatgataaag aaattgcaaa gaatcttcgt gacaacttcc cccaccctta tagggagcaa
     7081 aacgctagag attttattag tttttgtttg gcaactccag atgttaaaca acttagctat
     7141 gctatttttt atcaagaaag ggctattgga agtatcagcc taacatttga agaagatacc
     7201 tctattaata aaaatgctga attaggttac tggcttgcta ggaactattg gggcaaaggg
     7261 atagcaacaa atgcagtaaa agaaatatgc aaaattgcct ttgaaaaata aaaccttaac
     7321 aaaattcatg ctaatgtata ttcctacaat agagggtcaa gtaaagtatt ggaaaaatgt
     7381 ggttttaaga ttgaagaata ctgtcacaat tcataataaa gaatagaaac atgattgatt
     7441 gccatgtata tagtttaatt caaccgcaat agcatttatt agaattaacc tactttttaa
     7501 taacagaata agtttttccc ctctattaat ttcttatgca tctttgtatt tttatgaaaa
     7561 gctagccaat gcatatttcc atacatcaat atggtggtgg cttacaacca atataaatta
     7621 aatacgtttt aaagaataca catttttgcc ctataggcag agtgtgtatt tttttctctt
     7681 tttttgaaat ttatcgaaga tttaacgccc tcccaccgtg ataggagtaa gcaaggttat
     7741 ttaactcctt gcgatggaaa gagggtgaaa tcttatggtt gatgaaaaga caattgaaca
     7801 tcaattcgac agtttctgta aaacagtttt gcgtaactat gctagagata tttatgacga
     7861 aaataaacgc ataaatgatt atttggtatc tctcgaatct ttgtcacttg cagaattaag
     7921 taaattgagt attttagatg attatgattc taactacatc tgtatggttt cttacgacta
     7981 caacatacga attgaagatg tattaatggc acaagcaatc ggaaaactta caaaaagaaa
     8041 acaagatata attctacttt cattctttct caacatgaca aatgctgaca tagcaacatt
     8101 gatggattta gcagaaaata ccatacatta tcacaaaaca aatgcactaa aaaagttgaa
     8161 agaactcatg gaggaacatt gaaatgaaac ctactaaaga agtattacct tttacaatta
     8221 ttttacttgc tgtacatagc gatgtaaatg caataaacgg aatacttaaa cattttgaac
     8281 actatatcat tcgtctttca cagaaaactt tatttgatga atacggaaat ccctatattc
     8341 atgtagaaga agaaacaaag cgaatgctag gaacaaaact aatcactgct attttgagat
     8401 ttaatttgtc ttaatctcgc cctctctcca tgtatcaagc tatttggtac atggagaatc
     8461 actaattatt tgtctataaa agcccacaag ctattgtgat tttttatagg caaatcaatg
     8521 ccgactgttc tttgacaact gaataaagta gatagatacg tttgtgatac agatagccaa
     8581 caaatactat acgccatgac cttaatcaag agagctacta tatagtgatt tgtgaataac
     8641 ctttggaacg gttgttttgc cgtaacctgt accacagtat aatgatacac ctgtatgaca
     8701 cggttctgcc cataagaatg ggattggttg aaataccaat ggagcttacc aaagccatct
     8761 atctacttct gaactacgaa catataaagg agtgatacat tctatgaaca atactgatgt
     8821 acctatttgg gaaaaatata ccttgacgat tgaagaagcg tcaaaatact ttcgtattgg
     8881 agagaaaaaa ttacgtaaac ttgctgatga aaaccttgat tctggctggg tcattatgaa
     8941 tagcaatcgc attcaaataa agagaaaaca atttgagaaa atcgttgata cacttgactt
     9001 tatctaatga aattgagcct tatatgttat aatattcata tgacgtatca agctcaattc
     9061 ggttattgag aggagcttct tatcatgtca actgaaaaaa gacgagataa taaagataga
     9121 attttaagaa ctggagagag ccagagaaaa gatggaagat acgcatataa gtatgtatat
     9181 tcatttggta aaccacaatt tgtttactct tggaaacttg tacctactga taaaccccca
     9241 aagggaaaac gtgatgatat atcattaagg gataaggaaa aagcaataca aaatgacctt
     9301 gatgatagca ttgacactat tggtaagaaa atgacagttt gtcagttata cgctaaaaag
     9361 aatgtactaa gaaagaatat ccgacttaac actaaaaaag gacgccatta tcttatgaag
     9421 attcttaaca aggagtgatt ctgtgaagag atgtattgta gtagtggaat agtcaaaaac
     9481 ataatatata ttaaaggaga gatttaaata tgactattcc aagttcaaat aaggtatatc
     9541 caagaagtaa tgattatcaa actgtatatc ttaaaaatgt aataacaagg gaaaatatag
     9601 aagttggaga ttacacaata tataatgact tttataatga cccaagagat tttgagaaaa
     9661 acaatgtatt gtatcattac cctataaaca atgataaatt aataattggt aagttttgct
     9721 caatagcatg taatgcaaaa tttctaatga ctagtggaaa tcactcaatg aaatcaaaat
     9781 ccacatatac ttttcccatc ttttatgaag aatggaaact cgatatcaac catataacgg
     9841 acgcttggga caataagggt aacattataa ttggaaatga tgtgtggata ggttatgatt
     9901 ctataattat gtcaggtgta aatattggtg atggtgcaat tattggaaca agagcagtag
     9961 ttactaatga cgttccaccg tattctattg ttggaggagt acctgcaaaa attataaaaa
    10021 agagatttaa taatgataca atttcaaaat tattagaaat taaatggtgg gattggccat
    10081 ataaaaaaat tcaatcaaac attaagcata ttcaatcagg aaatattgat aaattagttt
    10141 aatattttat aatttattta tattaaactt tactttaata atcattttat aagagctttt
    10201 tcaaaatttg tatattattt taatatatat aaatttaata caacattaaa taaaataaaa
    10261 agtaaagtta cttaataaaa agttacttta ctttttatta tttaaattcc tgtttttatt
    10321 ataataggta aaattctatt aaactagttc acattttcat tattattgat atattatata
    10381 tgaatatacc attttgtttt ttaataaaaa atcatgctac atcaatagta agcaactatt
    10441 aatgtagcat gattttttgt atctaaataa tcttagtatt tacctatcaa tatagattga
    10501 tatatcaaaa actatagtct tctatattct tctcttttta gcttttggtt acttagatag
    10561 taatcaattt catcaattag acgttgttta tcatcaggta atacaccttt taaattagca
    10621 taatttgatg catgattact tctaaataca attttttcat tagcatctat attctttatc
    10681 atctctttaa tttcttgtaa cacagcctta tcctctagta ttgtaaactc tcctgcctta
    10741 agtaaatcgt aaagttcagt attaggttct accattaaac taagtacacc cacataatct
    10801 ggtgaaattg ctcctaacat ttttcctgta tcaactgcat gctgatgtgt ttttttagtt
    10861 cctccaagac ctgctattac agtggctgat aatttaatcc cacttttttt aacttttcta
    10921 ccaactttta ttaattgttc actactaaaa cctttcttaa tatcttctaa tacttcattg
    10981 cttccacttt caagccctag ataaatcatt ttaacaccaa gttttcttaa ttctttaagt
    11041 tcatcatcag attttttctc tatagattta ggagagccgt acatagtaat tctttcacac
    11101 tctggaaaaa cttcttttat atataaaata atatctctta atttctccat tggtattatc
    11161 aatgcatctc catctgctaa gaatattctt tctacatgct tataatatct tctaaatata
    11221 tcaatttcat tttttattac ttctagtggc tttattttaa attttttaga tttgtacata
    11281 ctacaaaacg tacatttgtt atgagaacat cctagtgtga cttgtattat aagactataa
    11341 gcctcacttg gtggtctgta aagtggcata tcgtattcc
//
LOCUS       DAEPUT010000235         3600 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.guided.168, whole genome shotgun sequence.
ACCESSION   DAEPUT010000235 DAEPUT010000000
VERSION     DAEPUT010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3600
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.guided.168"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            107..190
                     /locus_tag="KRL22_004044"
     CDS             107..190
                     /locus_tag="KRL22_004044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBH1274416.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            315..1052
                     /gene="erm(B)"
                     /locus_tag="KRL22_004045"
     CDS             315..1052
                     /gene="erm(B)"
                     /locus_tag="KRL22_004045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBH1274417.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            997..1170
                     /locus_tag="KRL22_004046"
     CDS             997..1170
                     /locus_tag="KRL22_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine methyltransferase"
                     /protein_id="HBH1274418.1"
                     /translation="MSKYCLFLIVIYYLTGGNNSMSRFCKFGKLHVTKGNVDKLLGIL
                     LTASKELKRSGPH"
     gene            1414..1653
                     /locus_tag="KRL22_004047"
     CDS             1414..1653
                     /locus_tag="KRL22_004047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1274419.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSLIESGKSDPTL
                     KTLERIAELTNSTLVIDLIPNELEQVELQIEEEKQ"
     gene            2048..3538
                     /locus_tag="KRL22_004048"
     CDS             2048..3538
                     /locus_tag="KRL22_004048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBH1274420.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KKSMIGGRGVVLTSEEAIHENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTLIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKLVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREALGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALSEFFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
BASE COUNT         1341 a          562 c          630 g         1067 t
ORIGIN      
        1 aaaaagctta gatttttgtc ttgacaactg aaccactata ttgtataata ggaattgaag
       61 ttaaattaga tgctaaaaat ttgtaattaa gaaggaggga ttcgtcatgt tggtattcca
      121 aatgcgtaat gtagataaaa catctactgt tttgaaacag actaaaaaca gtgattacgc
      181 agataaataa atacgttaga ttaattccta ccagtgacta atcttatgac tttttaaaca
      241 gataactaaa attacaaaca aatcgtttaa cttctgtatt tatttataga tgtaatcact
      301 tcaggagtga ttacatgaac aaaaatataa aatattctca aaacttttta acgagtgaaa
      361 aagtactcaa ccaaataata aaacaattga atttaaaaga aaccgatacc gtttacgaaa
      421 ttggaacagg taaagggcat ttaacgacga aactggctaa aataagtaaa caggtaacgt
      481 ctattgaatt agacagtcat ctattcaact tatcgtcaga aaaattaaaa ctgaacattc
      541 gtgtcacttt aattcaccaa gatattctac agtttcaatt ccctaacaaa cagaggtata
      601 aaattgttgg gaatattcct taccatttaa gcacacaaat tattaaaaaa gtggtttttg
      661 aaagccatgc gtctgacatc tatctgattg ttgaagaagg attctacaag cgtaccttgg
      721 atattcaccg aacactaggg ttgctcttgc acactcaagt ctcgattcag caattgctta
      781 agctgccagc ggaatgcttt catcctaaac caaaagtaaa cagtgtctta ataaaactta
      841 cccgccatac cacagatgtt ccagataaat attggaagct atatacgtac tttgtttcaa
      901 aatgggtcaa tcgagaatat cgtcaactgt ttactaaaaa tcagtttcat caagcaatga
      961 aacacgccaa agtaaacaat ttaagtaccg ttacttatga gcaagtattg tctattttta
     1021 atagttatct attatttaac gggaggaaat aattctatga gtcgcttttg taaatttgga
     1081 aagttacacg ttactaaagg gaatgtagat aaattattag gtatactact gacagcttcc
     1141 aaggagctaa agcgctcggg accccattaa gtatttttaa aagcatggtc gcaagtttca
     1201 ctagcagcca tgcttttatt gaatcattgt aggacatttt aaagataatt gcccacttta
     1261 aaattaaaca tgtgcttaga atcgttctag gcaacaccaa taacaatcac taatcacaag
     1321 tgatttgtga ttaatcactt gtgatttaca aggtgtaacg atataattaa atggaaaacg
     1381 tgcaaaatat ttacataaac aggagggaga aacttggaac tagcatttag agaaagctta
     1441 aaaaagatga gaggtaccaa atcaaaagaa aaattctccc aagaattaga aatgagtaga
     1501 tcaaattatt cattgattga atcaggaaaa tcagatccga cattaaaaac attggaacga
     1561 attgcagaat tgacaaactc aaccttagtt attgacttaa ttcctaatga attagaacaa
     1621 gtagagttgc aaatagaaga agagaagcaa tgattgtcgt taatatattt aacgaaattg
     1681 ttgcttattt tttttaaaag cggtatacta gatataacga aacaacgaac tgaataaaga
     1741 atacaaaaaa agagccacga ccaacttatt ttccgccaag aaaataagtt gcgagcctta
     1801 attgattacc accaatcaat taaagaagtc gagacccgaa atttggtaaa gtatttaatt
     1861 actttattaa tcagatactt aaatatctgt aaacccatta tatcgggttt ttgagggaat
     1921 ttcaagtctt taagaagata ccaggcaatc aattaagaaa aacttagttg attgcctttt
     1981 ttgttgtgat tcaactttga tcgtagcttc taactaatta attttcgtaa gaaaggagaa
     2041 cagctgaatg aatatccctt ttgttgtaga aactgtgctt catgacggct tgttaaagta
     2101 caaatttaaa aatagtaaaa ttcgctcaat cactaccaag ccaggtaaaa gcaaaggggc
     2161 tatttttgcg tatcgctcaa aaaaaagcat gattggcgga cgtggcgttg ttctgacttc
     2221 cgaagaagcg attcacgaaa atcaagatac atttacgcat tggacaccaa acgtttatcg
     2281 ttatggtacg tatgcagacg aaaaccgttc atacacgaaa ggacattctg aaaacaattt
     2341 aagacaaatc aataccttct ttattgattt tgatattcac acggcaaaag aaactatttc
     2401 agcaagcgat attttaacaa cagctattga tttaggtttt atgcctacgt taattatcaa
     2461 atctgataaa ggttatcaag catattttgt tttagaaacg ccagtttatg tgacttcaaa
     2521 atcagaattt aaatctgtca aagcagccaa aataatctcg caaaatatcc gagaatattt
     2581 tggaaagtct ttgccagttg atctaacgtg caatcatttt gggattgctc gtataccaag
     2641 aacggacaat gtagaatttt ttgatcccaa ttaccgttat tctttcaaag aatggcaaga
     2701 ttggtctttc aaacaaacag ataataaggg ctttactcgt tcaagtctaa cggttttaag
     2761 cggtacagaa ggcaaaaaac aagtagatga accctggttt aatctcttat tgcacgaaac
     2821 gaaattttca ggagaaaagg gtttaatagg gcgtaataac gtcatgttta ccctctcttt
     2881 agcctacttt agttcaggct attcaatcga aacgtgcgaa tataatatgt ttgagtttaa
     2941 taatcgatta gatcaaccct tagaagaaaa agaagtgatt aaacttgtta gaagtgccta
     3001 ttcagaaaac tatcaagggg ctaataggga atacattacc attctttgca aagcttgggt
     3061 atcaagtgat ttaaccagta aagatttatt tgtccgtcaa gggtggttta aattcaagaa
     3121 aaaaagaagt gaacgtcaac gtgttcattt gtcagaatgg aaagaagatt taatggctta
     3181 tattagcgaa aaaagtgatg tatacaagcc ttatttggtg acgactaaaa aagagattag
     3241 agaagcgcta ggcattcctg agcggacatt agataaattg ctgaaggtac tgaaggcgaa
     3301 tcaggaaatt ttctttaaga ttaaaccagg aagaaatggt ggcattcaac ttgctagtgt
     3361 taaatcattg ttgctatcga tcattaaagt aaaaaaagaa gaaaaagaaa gctatataaa
     3421 ggcgctgtca gagttttttg acttagaaca tacattcatt caagagactt taaacaagct
     3481 agcagaacgc ccaaaaacgg acacacaact cgatttgttt agctatgata caggctgaaa
     3541 atggaagaag ttttaattga tgtataatgg tatcgtaatt taagacactt caagagacat
//
LOCUS       DAEPUT010000236         2367 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 8
            SAMN13376316-rid12478433.guided.188, whole genome shotgun sequence.
ACCESSION   DAEPUT010000236 DAEPUT010000000
VERSION     DAEPUT010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376316
            Sequence Read Archive: SRR10518515
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069707.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069707.1
            Genome Coverage       :: 323x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:21:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 3,967
            Genes (coding)                    :: 3,893
            CDSs (with protein)               :: 3,893
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 34 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 7 of 74
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2367
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376316-rid12478433.guided.188"
                     /strain="8"
                     /host="Animal"
                     /db_xref="taxon:1496"
                     /country="China: ShaoXing"
                     /collection_date="2017"
     gene            <1..91
                     /locus_tag="KRL22_004049"
     CDS             <1..91
                     /locus_tag="KRL22_004049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1274421.1"
                     /translation="ACHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            92..1531
                     /locus_tag="KRL22_004050"
                     /note="aph(2'')-Ia"
     CDS             92..1531
                     /locus_tag="KRL22_004050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBH1274422.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1661..>2367)
                     /locus_tag="KRL22_004051"
     CDS             complement(1661..>2367)
                     /locus_tag="KRL22_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HBH1274423.1"
                     /translation="SEKNYPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIG
                     FMIQSGESEETWTTFFEYLKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHF
                     LRNIFTTIPKKNSKSFREAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDD
                     GFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDL
                     HDEWIYSSRKYINFDK"
BASE COUNT          897 a          244 c          418 g          808 t
ORIGIN      
        1 agcttgccat gtatatgaaa aattaggtgg taaaaatgat tataaagatg aaatagtata
       61 tgtatatgat tatgaaaaag gtgataaata aatgaatata gttgaaaatg aaatatgtat
      121 aagaacttta atagatgatg attttccttt gatgttaaaa tggttaactg atgaaagagt
      181 attagaattt tatggtggta gagataaaaa atatacatta gaatcattaa aaaaacatta
      241 tacagagcct tgggaagatg aagtttttag agtaattatt gaatataaca atgttcctat
      301 tggatatgga caaatatata aaatgtatga tgagttatat actgattatc attatccaaa
      361 aactgatgag atagtctatg gtatggatca atttatagga gagccaaatt attggagtaa
      421 aggaattggt acaagatata ttaaattgat ttttgaattt ttgaaaaaag aaagaaatgc
      481 taatgcagtt attttagacc ctcataaaaa taatccaaga gcaataaggg cataccaaaa
      541 atctggtttt agaattattg aagatttgcc agaacatgaa ttacacgagg gcaaaaaaga
      601 agattgttat ttaatggaat atagatatga tgataatgcc acaaatgtta aggcaatgaa
      661 atatttaatt gagcattact ttgataattt caaagtagat agtattgaaa taatcggtag
      721 tggttatgat agtgtggcat atttagttaa taatgaatac atttttaaaa caaaatttag
      781 tactaataag aaaaaaggtt atgcaaaaga aaaagcaata tataattttt taaatacaaa
      841 tttagaaact aatgtaaaaa ttcctaatat tgaatattcg tatattagtg atgaattatc
      901 tatactaggt tataaagaaa ttaaaggaac ttttttaaca ccagaaattt attctactat
      961 gtcagaagaa gaacaaaatt tgttaaaacg agatattgcc agttttttaa gacaaatgca
     1021 cggtttagat tatacagata ttagtgaatg tactattgat aataaacaaa atgtattaga
     1081 agagtatata ttgttgcgtg aaactattta taatgattta actgatatag aaaaagatta
     1141 tatagaaagt tttatggaaa gactaaatgc aacaacagtt tttgagggta aaaagtgttt
     1201 atgccataat gattttagtt gtaatcatct attgttagat ggcaataata gattaactgg
     1261 aataattgat tttggagatt ctggaattat agatgaatat tgtgatttta tatacttact
     1321 tgaagatagt gaagaagaaa taggaacaaa ttttggagaa gatatattaa gaatgtatgg
     1381 aaatatagat attgagaaag caaaagaata tcaagatata gttgaagaat attatcctat
     1441 tgaaactatt gtttatggaa ttaaaaatat taaacaggaa tttatcgaaa atggtagaaa
     1501 agaaatttat aaaaggactt ataaagattg attatataat atatgaaaag ctattataaa
     1561 agacattagt attaaatagt ttaaaaaaat gaaaaataat aaaggaagtg agtcaagtcc
     1621 agactcctgt gtaaaatgct atacaatgtt tttaccattt ctacttatca aaattgatgt
     1681 attttcttga agaataaatc cattcatcat gtaggtccat aagaacggct ccaattaagc
     1741 gattggctga tgtttgattg gggaagatgc gaataatctt ttctcttctg cgtacttctt
     1801 gattcagtcg ttcaattaga ttggtactct ttagtcgatt gtgggaattt ccttgtacgg
     1861 tatattgaaa ggcgtcttcg aatccatcat ccaatgatgc gcaagctttt gaatattttg
     1921 gttgatcgat ataatcatga atcaatcgat ttttagcctc acgcgctaag ttaatatctg
     1981 tgaacttaaa aattccttta acagcttctc tgaaagattt tgaatttttt ttaggaatgg
     2041 tggtaaagat atttcttagg aagtgaactt ggcatctttg ccaacttacg ttggtgaagg
     2101 attttctaat ggcagagact aatcctttgt gcgcatcaga aataacgagt tccgtacctt
     2161 gtaaaccgcg ttcttttagg tattcaaaaa atgttgtcca ggtctcttcg ctttcgccac
     2221 tttgaatcat gaagccgata atttcacggt cgccatcttt ggttattcca atcgctatat
     2281 gacagctttt tgagagtact cgattttctt ctcgtacttt tatatagagt acatcggtca
     2341 ttaagtaagg ataatttttt tctgata
//
